24 CFR 880.502 - Term of contract.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Contract § 880.502 Term of contract. (a) Term (except for Manufactured Home Parks). The term of the contract will be as follows: (1) For assisted units in a project financed with the aid of a loan insured or... Federal government, the term will be 20 years. (2) For assisted units in a project financed other than as...

24 CFR 880.502 - Term of contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Contract § 880.502 Term of contract. (a) Term (except for Manufactured Home Parks). The term of the contract will be as follows: (1) For assisted units in a project financed with the aid of a loan insured or... Federal government, the term will be 20 years. (2) For assisted units in a project financed other than as...

24 CFR 880.502 - Term of contract.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Contract § 880.502 Term of contract. (a) Term (except for Manufactured Home Parks). The term of the contract will be as follows: (1) For assisted units in a project financed with the aid of a loan insured or... Federal government, the term will be 20 years. (2) For assisted units in a project financed other than as...

Potential of Targeting PDE1C/2A for Suppressing Metastatic Ovarian Cancers

DTIC Science & Technology

2014-07-01

Shuang Huang CONTRACTING ORGANIZATION: GEORGIA HEALTH SCIENCES UNIVERSITY RESEARCH INSTITUTE, INC. Augusta , GA 30912 REPORT DATE: July 2014 TYPE...WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Georgia Regents University Research...Institute Augusta , GA 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel

Court Cases Involving Contracts for School Districts

ERIC Educational Resources Information Center

Allen, L. Hank

2011-01-01

The purpose of this research was to analyze trends in the United States regarding contract disputes that exist in school districts. Court cases were identified at the state and federal level to determine the outcomes and the fact patterns of contract disputes. To gain the knowledge of how courts handle cases of contractual breach, contracts…

Differential activation of motor units in the wrist extensor muscles during the tonic vibration reflex in man.

PubMed Central

Romaiguère, P; Vedel, J P; Azulay, J P; Pagni, S

1991-01-01

1. Single motor unit activity was recorded in the extensor carpi radialis longus and extensor carpi radialis brevis muscles of five healthy human subjects, using metal microelectrodes. 2. Motor units were characterized on the basis of their twitch contraction times and their force recruitment thresholds during voluntary imposed-ramp contractions. 3. The discharge patterns of forty-three motor units were studied during tonic vibration reflex elicited by prolonged (150 s) trains of vibration (30 Hz) applied to the distal tendons of the muscles. The temporal relationships between the individual small tendon taps of the vibratory stimulus and the motor unit impulses were analysed on dot raster displays and post-stimulus time histograms. 4. After tendon taps, the impulses of motor units with long twitch contraction times (mean +/- S.D., 47.2 +/- 10.7 ms) and low recruitment thresholds (0.88 +/- 0.6 N) formed a single narrow peak (P1) with a latency (22.7 +/- 1.4 ms) which was comparable to that of the tendon jerk in the extensor carpi radialis muscles. These motor units were named 'P1 units'. On the other hand, the response of motor units with shorter twitch contraction times (31.1 +/- 3.3 ms) and higher recruitment thresholds (3.21 +/- 1.3 N) showed two peaks: a short latency (23.4 +/- 1.3 ms) P1 peak similar to the previous one and a P2 peak occurring 9.4 +/- 1.2 ms later. These motor units were named 'P1-P2 units'. 5. When the reflex contraction increased slowly, the P1 peaks of 'P1-P2 units' were clearly predominant at the beginning of the contraction, during the rising phase of the motor unit discharge frequency, while the P2 peaks became predominant when the units had reached their maximal discharge frequency. 6. Increasing the tendon vibration frequency (35, 55, 75, 95 Hz) did not modify the 'P1 unit' discharge pattern. Due to interference between vibration period and peak latencies, increasing the vibration frequency caused the P1 and P2 peaks of 'P1-P2 units' to overlap. 7. Superficial cutaneous stimulation of the dorsal side of the forearm during tendon vibration noticeably decreased the P1 peaks in both types of motor units. In the P2 peaks it could result in either a decrease or an increase but the average effect was a slight increase. 8. When applied 10 s before tendon vibration, cutaneous stimulation considerably suppressed the tonic vibration reflex.(ABSTRACT TRUNCATED AT 400 WORDS) PMID:1822565

Electromyographic analysis of exercise resulting in symptoms of muscle damage.

PubMed

McHugh, M P; Connolly, D A; Eston, R G; Gleim, G W

2000-03-01

Surface electromyographic (EMG) signals were recorded from the hamstring muscles during six sets of submaximal isokinetic (2.6 rad x s(-1)) eccentric (11 men, 9 women) or concentric (6 men, 4 women) contractions. The EMG per unit torque increased during eccentric (P < 0.01) but not during concentric exercise. Similarly, the median frequency increased during eccentric (P < 0.01) but not during concentric exercise. The EMG per unit torque was lower for submaximal eccentric than maximum isometric contractions (P < 0.001), and lower for submaximal concentric than maximum isometric contractions (P < 0.01). The EMG per unit torque was lower for eccentric than concentric contractions (P < 0.05). The median frequency was higher for submaximal eccentric than maximum isometric contractions (P < 0.001); it was similar, however, between submaximal concentric and maximum isometric contractions (P = 0.07). Eccentric exercise resulted in significant isometric strength loss (P < 0.01), pain (P < 0.01) and muscle tenderness (P < 0.05). The greatest strength loss was seen 1 day after eccentric exercise, while the most severe pain and muscle tenderness occurred 2 days after eccentric exercise. A lower EMG per unit torque is consistent with the selective recruitment of a small number of motor units during eccentric exercise. A higher median frequency during eccentric contractions may be explained by selective recruitment of fast-twitch motor units. The present results are consistent with the theory that muscle damage results from excessive stress on a small number of active fibres during eccentric contractions.

A Note on the Stability of the Job Descriptive Index (J. D. I.).

DTIC Science & Technology

1978-05-01

tOE PARK DEPT OF PSYCHOLOGY I D A 18 ______ END F I L V E O ‘ cli._____ 8— 780DC I I • ~~ j~2.8 ~I2.5 1111 ’ • 40 llhII~.0 ~II L8 • I 25 llIlI...Training Research Programs , Psycholog ica l Sciences Division ,1 ; Office of Nava l Research under Contract No. N0001 4-75-C-0884, ~J Contract...AND A D D R E S S 10. P R O G R A M ELEMENT , PROJE CT , TASK A R E A & WORK UNIT NUMBER S Departme nt of Psychology 6 l l53 N University of

48 CFR 19.309 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... performed in the United States or its outlying areas. (d) Insert the clause at 52.219-28, Post-Award Small... Business Programs 19.309 Solicitation provisions and contract clauses. (a)(1) Insert the provision at 52... when the contract will be performed in the United States or its outlying areas. (2) Use the provision...

48 CFR 19.309 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... performed in the United States or its outlying areas. (d) Insert the clause at 52.219-28, Post-Award Small... Business Programs 19.309 Solicitation provisions and contract clauses. (a)(1) Insert the provision at 52... when the contract will be performed in the United States or its outlying areas. (2) Use the provision...

48 CFR 217.172 - Multiyear contracts for supplies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of units to be procured through the contract; and (2) In the case of a contract for procurement of aircraft, the budget request includes full funding of procurement funds for production beyond advance procurement activities of aircraft units to be produced in the fiscal year covered by the budget. (d)(1) The...

25 CFR 136.1 - Repayment contracts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Repayment contracts. 136.1 Section 136.1 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES FORT HALL INDIAN IRRIGATION PROJECT, IDAHO § 136.1 Repayment contracts. A rehabilitation program was established on the Fort Hall Unit...

Blood Biomarker Profile of TBI Associated Cognitive Impairment Among Old and Young Veterans

DTIC Science & Technology

2016-10-01

INVESTIGATOR: Kristine Yaffe, MD CONTRACTING ORGANIZATION: Northern California Institute for Research and Education San Francisco, CA 94121 REPORT...MD 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Northern California Institute for Research and Education ...and Resiliency for Dementia: Comparison of Male and Female Veterans (Yaffe: PI) Time Commitment: 1.2 calendar months Supporting Agency: DOD

Anatomic and physiological characteristics of the ferret lateral rectus muscle and abducens nucleus.

PubMed

Bishop, Keith N; McClung, J Ross; Goldberg, Stephen J; Shall, Mary S

2007-11-01

The ferret has become a popular model for physiological and neurodevelopmental research in the visual system. We believed it important, therefore, to study extraocular whole muscle as well as single motor unit physiology in the ferret. Using extracellular stimulation, 62 individual motor units in the ferret abducens nucleus were evaluated for their contractile characteristics. Of these motor units, 56 innervated the lateral rectus (LR) muscle alone, while 6 were split between the LR and retractor bulbi (RB) muscle slips. In addition to individual motor units, the whole LR muscle was evaluated for twitch, tetanic peak force, and fatigue. The abducens nucleus motor units showed a twitch contraction time of 15.4 ms, a mean twitch tension of 30.2 mg, and an average fusion frequency of 154 Hz. Single-unit fatigue index averaged 0.634. Whole muscle twitch contraction time was 16.7 ms with a mean twitch tension of 3.32 g. The average fatigue index of whole muscle was 0.408. The abducens nucleus was examined with horseradish peroxidase conjugated with the subunit B of cholera toxin histochemistry and found to contain an average of 183 motoneurons. Samples of LR were found to contain an average of 4,687 fibers, indicating an LR innervation ratio of 25.6:1. Compared with cat and squirrel monkeys, the ferret LR motor units contract more slowly yet more powerfully. The functional visual requirements of the ferret may explain these fundamental differences.

DEVELOPMENT AND USE OF RARE EARTH TRACERS IN THE MODIFIED DRY PARTICLE DEPOSITION SYSTEM (FORMERLY "DUST" CHAMBER)

EPA Science Inventory

This report was submitted in partial fulfillment of Contract 68-D5-0040 by Research Triangle Institute under the sponsorship of the United States Environmental Protection Agency. This report covers a period from October 1, 1996 to September 30, 1999 and includes activities fun...

48 CFR 1352.237-70 - Security processing requirements-high or moderate risk contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... premises of any Department of Commerce owned, leased, or controlled facility in the United States or... Nationals (Non-U.S. Citizens). To be employed under this contract within the United States, non-U.S. citizens must have: (1) Official legal status in the United States; (2) Continuously resided in the United...

Shoreside Alternative Energy Evaluation

DTIC Science & Technology

2002-09-01

U.S. Coast Guard Research and Development Center 1082 Shennecossett Road, Groton, CT 06340-6096 Report No. CG-D-02-02 SHORESIDE ALTERNATIVE ENERGY...standard, specification, or regulation. Marc B. Mandler, Ph.D. Technical Director United States Coast Guard Research & Development Center 1082 ...Coast Guard Research and Development Center 1082 Shennecossett Road Groton, CT 06340-6096 10. Work Unit No. (TRAIS) 11. Contract or Grant No. 12

24 CFR 886.309 - Housing assistance payment to owners.

Code of Federal Regulations, 2011 CFR

2011-04-01

... available as of the effective date of the Contract is not leased within 15 days of the effective date of the... Contract Rent for the unit for a vacancy period not exceeding 60 days from the effective date of the Contract provided that the Owner (1) has submitted a list of units leased as of the effective date and a...

24 CFR 886.309 - Housing assistance payment to owners.

Code of Federal Regulations, 2012 CFR

2012-04-01

... available as of the effective date of the Contract is not leased within 15 days of the effective date of the... Contract Rent for the unit for a vacancy period not exceeding 60 days from the effective date of the Contract provided that the Owner (1) has submitted a list of units leased as of the effective date and a...

24 CFR 886.309 - Housing assistance payment to owners.

Code of Federal Regulations, 2014 CFR

2014-04-01

... available as of the effective date of the Contract is not leased within 15 days of the effective date of the... Contract Rent for the unit for a vacancy period not exceeding 60 days from the effective date of the Contract provided that the Owner (1) has submitted a list of units leased as of the effective date and a...

24 CFR 886.309 - Housing assistance payment to owners.

Code of Federal Regulations, 2013 CFR

2013-04-01

... available as of the effective date of the Contract is not leased within 15 days of the effective date of the... Contract Rent for the unit for a vacancy period not exceeding 60 days from the effective date of the Contract provided that the Owner (1) has submitted a list of units leased as of the effective date and a...

48 CFR 252.225-7004 - Report of Intended Performance Outside the United States and Canada-Submission after Award.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Policy and International Contracting), OUSD(AT&L)DPAP(CPIC), Washington, DC 20301-3060. (d) Report format... CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7004... subcontractor will perform any part of this contract outside the United States and Canada that— (1) Exceeds $650...

48 CFR 252.225-7004 - Report of Intended Performance Outside the United States and Canada-Submission after Award.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Policy and International Contracting), OUSD(AT&L)DPAP(CPIC), Washington, DC 20301-3060. (d) Report format... CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7004... subcontractor will perform any part of this contract outside the United States and Canada that— (1) Exceeds $650...

24 CFR 883.603 - Term of contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., guaranteed or intended for purchase by the Federal government and for assisted units in newly constructed manufactured home parks, the term of the Contract will be 20 years. (2) For assisted units in a project owned... following provisions: (1) For assisted units in a project financed with the aid of a loan insured by the...

24 CFR 883.603 - Term of contract.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., guaranteed or intended for purchase by the Federal government and for assisted units in newly constructed manufactured home parks, the term of the Contract will be 20 years. (2) For assisted units in a project owned... following provisions: (1) For assisted units in a project financed with the aid of a loan insured by the...

24 CFR 883.603 - Term of contract.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., guaranteed or intended for purchase by the Federal government and for assisted units in newly constructed manufactured home parks, the term of the Contract will be 20 years. (2) For assisted units in a project owned... following provisions: (1) For assisted units in a project financed with the aid of a loan insured by the...

24 CFR 883.603 - Term of contract.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., guaranteed or intended for purchase by the Federal government and for assisted units in newly constructed manufactured home parks, the term of the Contract will be 20 years. (2) For assisted units in a project owned... following provisions: (1) For assisted units in a project financed with the aid of a loan insured by the...

24 CFR 883.603 - Term of contract.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., guaranteed or intended for purchase by the Federal government and for assisted units in newly constructed manufactured home parks, the term of the Contract will be 20 years. (2) For assisted units in a project owned... following provisions: (1) For assisted units in a project financed with the aid of a loan insured by the...

Motor unit recruitment strategies are altered during deep-tissue pain.

PubMed

Tucker, Kylie; Butler, Jane; Graven-Nielsen, Thomas; Riek, Stephan; Hodges, Paul

2009-09-02

Muscle pain is associated with decreased motor unit discharge rate during constant force contractions. As discharge rate is a determinant of force, other adaptations in strategy must explain force maintenance during pain. Our aim was to determine whether motor unit recruitment strategies are altered during pain to maintain force despite reduced discharge rate. Motor unit discharge behavior was recorded in two muscles, one with (quadriceps) and one without [flexor pollicis longus (FPL)] synergists. Motor units were recruited during matched low-force contractions with and without experimentally induced pain, and at higher force without pain. A total of 52 and 34 units were recorded in quadriceps and FPL, respectively, during low-force contractions with and without pain. Of these, 20 quadriceps and 9 FPL units were identified during both trials. The discharge rate of these units reduced during pain in both muscles [quadriceps: 8.7 (1.5) to 7.5 (1.3) Hz, p < 0.001; FPL: 11.9 (1.5) to 10.0 (1.7) Hz, p < 0.001]. All remaining units discharged only with or without pain, but not in both conditions. Only one-third of the additional units recruited during pain (quadriceps n = 7/19, FPL n = 3/15) were those expected given orderly recruitment of the motor unit pool as determined during higher-force contractions. We conclude that reduced motor unit discharge rate with pain is accompanied by changes in the population of units used to maintain force. The recruitment of new units is partly inconsistent with generalized inhibition of the motoneuron pool predicted by the "pain adaptation" theory, and provides the basis for a new mechanism of motor adaptation with pain.

48 CFR 46.307 - Fixed-price research and development contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.307 Fixed-price research and development... Development—Fixed-Price, in solicitations and contracts for research and development when (1) the primary... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Fixed-price research and...

48 CFR 42.705-1 - Contracting officer determination procedure.

Code of Federal Regulations, 2010 CFR

2010-10-01

... a multidivisional corporation under the cognizance of a corporate administrative contracting officer... organization. (2) Business units not under the cognizance of a corporate administrative contracting officer... accounting system capabilities. The contractor, contracting officer, and auditor must work together to make...

75 FR 6685 - Section 8 Housing Assistance Payments Program-Contract Rent Annual Adjustment Factors, Fiscal...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... contract rent is reduced by comparability): The Table 1 Contract Rent AAF is used for a unit occupied by a... rent to owner will not be reduced below the contract rent on the effective date of the HAP contract. III. When to Use Reduced Contract Rent AAFs (From Contract Rent AAF Table 2) In accordance with...

Risk Management and Performance in the Balkans Support Contract

DTIC Science & Technology

2005-01-01

Defense contracts-United States-Case studies . 2. United States. Army- Procurement-Case studies . 3. Bosnia and Hercegovina-History, Military-20ts...24 3.1. Assessment of GAO Cost Study .................................. 72 3.2. Comparison of Potential Sources of Nonperformance...accepting inappropriate risks, what can it do about it? Case studies of CSS contracts can provide some answers. In this report, we present a case study of

Global Entrepreneurship and the United States

DTIC Science & Technology

2010-09-01

Global Entrepreneurship and the United States by Zoltan J. Acs Laszlo Szerb Ruxton, MD 21204 for under contract number SBAHQ-09...SUBTITLE Global Entrepreneurship and the United States 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...3 2.1. Assessing Entrepreneurship ..................................................................................4 2.2. Stages of Development

Vastus lateralis surface and single motor unit EMG following submaximal shortening and lengthening contractions.

PubMed

Altenburg, Teatske M; de Ruiter, Cornelis J; Verdijk, Peter W L; van Mechelen, Willem; de Haan, Arnold

2008-12-01

A single shortening contraction reduces the force capacity of muscle fibers, whereas force capacity is enhanced following lengthening. However, how motor unit recruitment and discharge rate (muscle activation) are adapted to such changes in force capacity during submaximal contractions remains unknown. Additionally, there is limited evidence for force enhancement in larger muscles. We therefore investigated lengthening- and shortening-induced changes in activation of the knee extensors. We hypothesized that when the same submaximal torque had to be generated following shortening, muscle activation had to be increased, whereas a lower activation would suffice to produce the same torque following lengthening. Muscle activation following shortening and lengthening (20 degrees at 10 degrees /s) was determined using rectified surface electromyography (rsEMG) in a 1st session (at 10% and 50% maximal voluntary contraction (MVC)) and additionally with EMG of 42 vastus lateralis motor units recorded in a 2nd session (at 4%-47%MVC). rsEMG and motor unit discharge rates following shortening and lengthening were normalized to isometric reference contractions. As expected, normalized rsEMG (1.15 +/- 0.19) and discharge rate (1.11 +/- 0.09) were higher following shortening (p < 0.05). Following lengthening, normalized rsEMG (0.91 +/- 0.10) was, as expected, lower than 1.0 (p < 0.05), but normalized discharge rate (0.99 +/- 0.08) was not (p > 0.05). Thus, muscle activation was increased to compensate for a reduced force capacity following shortening by increasing the discharge rate of the active motor units (rate coding). In contrast, following lengthening, rsEMG decreased while the discharge rates of active motor units remained similar, suggesting that derecruitment of units might have occurred.

Research Methods to Develop Measures of Effectiveness of the United States Coast Guard’s Vessel Inspection and Boarding Program. Decision Support for Utilizing Measures of Effectiveness - Volume III

DTIC Science & Technology

1995-05-01

Eubank S.E. Albuquerque, NM 87123 Christopher Rodriguez Kevin Downer U.S. Coast Guard Research and Development Center 1082 Shennecossett Road Groton...standard, specifica )e n. ’OVVELOPj4 Commanding Officer United States Coast Guard Research & Development Center 1082 Shennecossett Road SGroton, CT...Work Unit No. (TRAIS) U.S. Coast Guard Sandia National Laboratories Research and Development Center 11. Contract or Grant No. 1515 Eubank SE 1082

Muscle vibration sustains motor unit firing rate during submaximal isometric fatigue in humans.

PubMed

Griffin, L; Garland, S J; Ivanova, T; Gossen, E R

2001-09-15

1. In keeping with the 'muscular wisdom hypothesis', many studies have documented that the firing rate of the majority of motor units decreased during fatiguing isometric contractions. The present study investigated whether the application of periodic muscle vibration, which strongly activates muscle spindles, would alter the modulation of motor unit firing rate during submaximal fatiguing isometric contractions. 2. Thirty-three motor units from the lateral head of the triceps brachii muscle were recorded from 10 subjects during a sustained isometric 20 % maximal voluntary contraction (MVC) of the elbow extensors. Vibration was interposed on the contraction for 2 s every 10 s. Twenty-two motor units were recorded from the beginning of the fatigue task. The discharge rate of the majority of motor units remained constant (12/22) or increased (4/22) with fatigue. Six motor units demonstrated a reduction in discharge rate that later returned toward initial values; these motor units had higher initial discharge rates than the other 16 motor units. 3. In a second series of experiments, four subjects held a sustained isometric 20 % MVC for 2 min and then vibration was applied as above for the remainder of the contraction. In this case, motor units initially demonstrated a decrease in firing rate that increased after the vibration was applied. Thus muscle spindle disfacilitation of the motoneurone pool may be associated with the decline of motor unit discharge rate observed during the first 2 min of the contraction. 4. In a third set of experiments, seven subjects performed the main experiment on one occasion and repeated the fatigue task without vibration on a second occasion. Neither the endurance time of the fatiguing contraction nor the MVC torque following fatigue was affected by the application of vibration. This finding calls into question the applicability of the muscular wisdom hypothesis to submaximal contractions.

A History of Instructional Methods in Uncontracted and Contracted Braille

ERIC Educational Resources Information Center

D'Andrea, Frances Mary

2009-01-01

This literature review outlines the history of the braille code as used in the United States and Canada, illustrating how both the code itself and instructional strategies for teaching it changed over time. The review sets the stage for the research questions of the recently completed Alphabetic Braille and Contracted Braille Study.

41 CFR 60-1.26 - Enforcement proceedings.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., the Attorney General may bring a civil action in the appropriate district court of the United States... civil action in the appropriate district court of the United States requesting a temporary restraining... Contracts OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS, EQUAL EMPLOYMENT OPPORTUNITY, DEPARTMENT OF LABOR...

26 CFR 1.953-1 - Income from insurance of United States risks.

Code of Federal Regulations, 2010 CFR

2010-04-01

... example 1 except that M Corporation cancels the contract on August 31, 1963. For 1963, the policy period under such contract as to A Corporation is July 1, 1963, to August 31, 1963. Example 3. The facts are... § 1.953-5, which is attributable to the reinsuring or the issuing of any insurance or annuity contract...

Intellectual Property Series. National Council of University Research Administrators.

ERIC Educational Resources Information Center

National Council of Univ. Research Administrators, Washington, DC.

Materials on intellectual property are presented to help university research administrators negotiate and administer sponsored research agreements. The nine units cover: patents and patent rights, patent rights under government contracts, university patent policies and practices, patent clauses in industrial research agreements, patent licensing…

75 FR 69715 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-15

... contract for future functional equivalence analyses of the GEPS 3 product. \\1\\ Notice of United States... GEPS contracts, a description of applicable GEPS contracts, formulas for prices, an analysis of the... information and volume commitments, do not alter the contracts' functional equivalency. Id. at 3-4. The Postal...

48 CFR 36.207 - Pricing fixed-price construction contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Pricing fixed-price... Contracting for Construction 36.207 Pricing fixed-price construction contracts. (a) Generally, firm-fixed... methods. (b) Lump-sum pricing shall be used in preference to unit pricing except when— (1) Large...

24 CFR 983.206 - HAP contract amendments (to add or substitute contract units).

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false HAP contract amendments (to add or... Contract § 983.206 HAP contract amendments (to add or substitute contract units). (a) Amendment to substitute contract units. At the discretion of the PHA and subject to all PBV requirements, the HAP contract...

48 CFR 35.015 - Contracts for research with educational institutions and nonprofit organizations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Contracts for research with educational institutions and nonprofit organizations. 35.015 Section 35.015 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.015 Contracts for research...

48 CFR 35.015 - Contracts for research with educational institutions and nonprofit organizations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Contracts for research with educational institutions and nonprofit organizations. 35.015 Section 35.015 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.015 Contracts for research...

48 CFR 35.015 - Contracts for research with educational institutions and nonprofit organizations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Contracts for research with educational institutions and nonprofit organizations. 35.015 Section 35.015 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.015 Contracts for research...

48 CFR 46.309 - Research and development contracts (short form).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Research and development contracts (short form). 46.309 Section 46.309 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.309 Research and development contracts...

Collaborative Multidisciplinary Sciences for Analysis and Design of Aerospace Vehicles. Volume 1

DTIC Science & Technology

2017-05-01

AEROSPACE VEHICLES Volume 1 5a. CONTRACT NUMBER FA8650-09-2-3938 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62201F 6. AUTHOR(S) Raymond M...S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBERDesign and Analysis Branch (AFRL/RQVC) Aerospace Vehicles Division Air Force Research...Laboratory, Aerospace Systems Directorate Wright-Patterson Air Force Base, OH 45433-7542 Air Force Materiel Command, United States Air Force Virginia

DoD Influenza Surveillance and Vaccine Effectiveness

DTIC Science & Technology

2014-02-28

controls – No analyses by flu subtype (over 90% of flu samples were H1N1) 21 • Adjusted Estimates of Vaccine Effectiveness – Population: Service...DoD Influenza Surveillance and Vaccine Effectiveness Armed Forces Health Surveillance Center (AFHSC) Naval Health Research Center (NHRC) United... Vaccine Effectiveness 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK

77 FR 10577 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-22

...-filed Postal Service request to enter into an additional International Business Reply Service contract... additional International Business Reply Service (IBRS) contract.\\1\\ The Postal Service asserts that the... United States Postal Service Filing of a Functionally Equivalent International Business Reply Service...

Research Directory for Manpower, Personnel, Training, and Human Factors, 1992

DTIC Science & Technology

1992-11-01

Malone 703-698-6225 Smart Contract Preparation Expediter (R) Ms Joan E Forester 410-278-2946 DSN:298-2946 (P) Mr R Cofod 703-359-0996 Soldier...Mike Hanuschik 513-255-3871 DSN:785-3871 Small Unit Maintenance Manpower Analyses (SUMMA) (R) Mr Edward Boyle 513-255-3871 DSN:785-3871 Smart Contract Preparation

48 CFR 14.203-1 - Transmittal to prospective bidders.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Solicitation of Bids 14.203-1 Transmittal to prospective... outside the United States shall be sent by electronic data interchange or air mail if security...

48 CFR 32.006-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REQUIREMENTS CONTRACT FINANCING 32.006-1 General. (a) Under Title 10 of the United States Code, the statutory..., agency head determinations and decisions under this section may be made for an individual contract or any...

NASA work unit system file maintenance manual

NASA Technical Reports Server (NTRS)

1972-01-01

The NASA Work Unit System is a management information system for research tasks (i.e., work units) performed under NASA grants and contracts. It supplies profiles on research efforts and statistics on fund distribution. The file maintenance operator can add, delete and change records at a remote terminal or can submit punched cards to the computer room for batch update. The system is designed for file maintenance by a person with little or no knowledge of data processing techniques.

The compensatory interaction between motor unit firing behavior and muscle force during fatigue

PubMed Central

De Luca, Carlo J.; Kline, Joshua C.

2016-01-01

Throughout the literature, different observations of motor unit firing behavior during muscle fatigue have been reported and explained with varieties of conjectures. The disagreement amongst previous studies has resulted, in part, from the limited number of available motor units and from the misleading practice of grouping motor unit data across different subjects, contractions, and force levels. To establish a more clear understanding of motor unit control during fatigue, we investigated the firing behavior of motor units from the vastus lateralis muscle of individual subjects during a fatigue protocol of repeated voluntary constant force isometric contractions. Surface electromyographic decomposition technology provided the firings of 1,890 motor unit firing trains. These data revealed that to sustain the contraction force as the muscle fatigued, the following occurred: 1) motor unit firing rates increased; 2) new motor units were recruited; and 3) motor unit recruitment thresholds decreased. Although the degree of these adaptations was subject specific, the behavior was consistent in all subjects. When we compared our empirical observations with those obtained from simulation, we found that the fatigue-induced changes in motor unit firing behavior can be explained by increasing excitation to the motoneuron pool that compensates for the fatigue-induced decrease in muscle force twitch reported in empirical studies. Yet, the fundamental motor unit control scheme remains invariant throughout the development of fatigue. These findings indicate that the central nervous system regulates motor unit firing behavior by adjusting the operating point of the excitation to the motoneuron pool to sustain the contraction force as the muscle fatigues. PMID:27385798

The compensatory interaction between motor unit firing behavior and muscle force during fatigue.

PubMed

Contessa, Paola; De Luca, Carlo J; Kline, Joshua C

2016-10-01

Throughout the literature, different observations of motor unit firing behavior during muscle fatigue have been reported and explained with varieties of conjectures. The disagreement amongst previous studies has resulted, in part, from the limited number of available motor units and from the misleading practice of grouping motor unit data across different subjects, contractions, and force levels. To establish a more clear understanding of motor unit control during fatigue, we investigated the firing behavior of motor units from the vastus lateralis muscle of individual subjects during a fatigue protocol of repeated voluntary constant force isometric contractions. Surface electromyographic decomposition technology provided the firings of 1,890 motor unit firing trains. These data revealed that to sustain the contraction force as the muscle fatigued, the following occurred: 1) motor unit firing rates increased; 2) new motor units were recruited; and 3) motor unit recruitment thresholds decreased. Although the degree of these adaptations was subject specific, the behavior was consistent in all subjects. When we compared our empirical observations with those obtained from simulation, we found that the fatigue-induced changes in motor unit firing behavior can be explained by increasing excitation to the motoneuron pool that compensates for the fatigue-induced decrease in muscle force twitch reported in empirical studies. Yet, the fundamental motor unit control scheme remains invariant throughout the development of fatigue. These findings indicate that the central nervous system regulates motor unit firing behavior by adjusting the operating point of the excitation to the motoneuron pool to sustain the contraction force as the muscle fatigues. Copyright © 2016 the American Physiological Society.

Prioritizing food safety and research

USDA-ARS?s Scientific Manuscript database

Recent publications have revealed that approximately 48 million individuals in the the United States of America contract foodborne illnesses each year, with associated costs estimated at $77.7 billion U.S. dollars (equivalent to ca. 87.5 trillion Korean won in the year 2012). The United States Depa...

OMC Compressor Case

NASA Technical Reports Server (NTRS)

Humphrey, W. Donald

1997-01-01

This report summarizes efforts expended in the development of an all-composite compressor case. Two pre-production units have been built, one utilizing V-CAP and one utilizing AFR-700B resin systems. Both units have been rig tested at elevated temperatures well above design limit loads. This report discusses the manufacturing processes, test results, and Finite Element Analysis performed. The V-CAP unit was funded by NASA-Lewis Research Center in 1994 under contract number NAS3- 27442 for Development of an All-Composite OMC Compressor Case. This contract was followed by an Air Force study in 1996 to build and identical unit using the AFR-700B resin system in place of the V-CAP system. The second compressor case was funded under U.S. Air Force contract F33615-93-D-5326, Advanced Materials for Aerospace Structures Special Studies (AMAS3), Delivery Order 0021 entitled "Advanced Polymeric Composite Materials and Structures Technology for Advanced High Temperature Gas Turbine Engines.' Initial studies using the V-CAP resin system were undertaken in 1993 under a NASA Lewis contract (NAS3-26829). A first prototype unit was developed in a joint program between Textron-Lycoming (now Allied Signal) and Brunswick (now Lincoln Composites). This unit included composite end closures using low density, high temperature molded end closures. The units was similar in size and shape to a titanium case currently used on the PT-21 0 engine and was funded as part of the integrated High Performance Turbine Engine Technology (EHPTET) initiative of DOD and NASA.

48 CFR 2035.70 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 2035.70 Contract clauses. (a) The contracting officer shall insert the following clause in all solicitations and contracts for research and development by private contractors and universities and for other technical services, as appropriate: (1) Section 2052.235-70...

30 CFR 1206.301 - Value basis for royalty computation.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) The gross value for royalty purposes shall be the sale or contract unit price times the number of units sold, Provided, however, That where the authorized officer determines: (1) That a contract of sale... whole or in part upon considerations other than the value of the commodities, or (2) That no bona fide...

43 CFR 3287.2 - When may BLM grant a suspension of unit obligations?

Code of Federal Regulations, 2012 CFR

2012-10-01

..., the unit operator is prevented from complying with such obligations, in whole or in part, by: (1) Acts... operator's inability to obtain an electrical sales contract, or when poor economics affect the electrical generation market, limiting the opportunity to obtain a viable sales contract. BLM may grant a suspension of...

30 CFR 1206.301 - Value basis for royalty computation.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) The gross value for royalty purposes shall be the sale or contract unit price times the number of units sold, Provided, however, That where the authorized officer determines: (1) That a contract of sale... whole or in part upon considerations other than the value of the commodities, or (2) That no bona fide...

43 CFR 3287.2 - When may BLM grant a suspension of unit obligations?

Code of Federal Regulations, 2014 CFR

2014-10-01

..., the unit operator is prevented from complying with such obligations, in whole or in part, by: (1) Acts... operator's inability to obtain an electrical sales contract, or when poor economics affect the electrical generation market, limiting the opportunity to obtain a viable sales contract. BLM may grant a suspension of...

30 CFR 1206.301 - Value basis for royalty computation.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) The gross value for royalty purposes shall be the sale or contract unit price times the number of units sold, Provided, however, That where the authorized officer determines: (1) That a contract of sale... whole or in part upon considerations other than the value of the commodities, or (2) That no bona fide...

30 CFR 206.301 - Value basis for royalty computation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... gross value for royalty purposes shall be the sale or contract unit price times the number of units sold, Provided, however, That where the authorized officer determines: (1) That a contract of sale or other... lease is not a bona fide transaction between independent parties because it is based in whole or in part...

43 CFR 3287.2 - When may BLM grant a suspension of unit obligations?

Code of Federal Regulations, 2013 CFR

2013-10-01

..., the unit operator is prevented from complying with such obligations, in whole or in part, by: (1) Acts... operator's inability to obtain an electrical sales contract, or when poor economics affect the electrical generation market, limiting the opportunity to obtain a viable sales contract. BLM may grant a suspension of...

Data Acquisition System(DAS) Sustaining Engineering

NASA Technical Reports Server (NTRS)

1998-01-01

This paper presents general information describing the Data Acquisition System contract, a summary of objectives, tasks performed and completed. The hardware deliverables which are comprised of: 1) Two ground DAS units; 2) Two flight DAS units; 3) Logistic spares; and 4) Shipping containers are described. Also included are the data requirements and scope of the contract.

48 CFR 917.7301-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 917.7301-1 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Program Research and Development Announcements 917.7301-1... in entering into arrangements for research, development, and related projects in specified areas of...

Educational Contracting and the Translation of Research into Practice: The Case of Data Coach Vendors in Delaware

ERIC Educational Resources Information Center

Farley-Ripple, Elizabeth; Jones, Akisha R.

2015-01-01

In the United States, federal and state accountability policies put demands on educational agencies that often exceed their capacity. As a result, a variety of educational organizations are contracted to design and implement policy. Programs and services offered by these contractors are not only instrumental in the process of mediating and…

Separation of Prior-Service Reentrants in the U.S. (United States) Navy: A Preliminary Analysis.

DTIC Science & Technology

1983-04-01

AND ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASK ’ Institute for Policy Research and Evaluation AREA & WORK UNIT NUMBERS N-253 Burrowes Building, PSU...enlistment a Percent of area reentrants in each district - . . - • . .. .. p. . ia OTHER TECHNICAL REPORTS OF TIllS PROJECTa As part of the project...bOffie of Naval Research Contract No. N00014-82-K-0262. • . . . . Distribution List Director Technology Programs Office of Naval Research (Code 200

46 CFR 381.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., material or commodities: (1) Procured, contracted for or otherwise obtained within or outside the United... advances funds or credits or guarantees the convertability of foreign currencies. (4) Procured, contracted...

46 CFR 381.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., material or commodities: (1) Procured, contracted for or otherwise obtained within or outside the United... advances funds or credits or guarantees the convertability of foreign currencies. (4) Procured, contracted...

Low-frequency oscillations of the neural drive to the muscle are increased with experimental muscle pain

PubMed Central

Negro, Francesco; Gizzi, Leonardo; Falla, Deborah

2012-01-01

We investigated the influence of nociceptive stimulation on the accuracy of task execution and motor unit spike trains during low-force isometric contractions. Muscle pain was induced by infusion of hypertonic saline into the abductor digiti minimi muscle of 11 healthy men. Intramuscular EMG signals were recorded from the same muscle during four isometric contractions of 60-s duration at 10% of the maximal force [maximal voluntary contraction (MVC)] performed before injection (baseline), after injection of isotonic (control) or hypertonic saline (pain), and 15 min after pain was no longer reported. Each contraction was preceded by three 3-s ramp contractions from 0% to 10% MVC. The low-frequency oscillations of motor unit spike trains were analyzed by the first principal component of the low-pass filtered spike trains [first common component (FCC)], which represents the effective neural drive to the muscle. Pain decreased the accuracy of task performance [coefficient of variation (CoV) for force: baseline, 2.8 ± 1.8%, pain, 3.9 ± 1.8%; P < 0.05] and reduced motor unit discharge rates [11.6 ± 2.3 pulses per second (pps) vs. 10.7 ± 1.7 pps; P < 0.05]. Motor unit recruitment thresholds (2.2 ± 1.2% MVC vs. 2.4 ± 1.6% MVC), interspike interval variability (18.4 ± 4.9% vs. 19.1 ± 5.4%), strength of motor unit short-term synchronization [common input strength (CIS) 1.02 ± 0.44 vs. 0.83 ± 0.22], and strength of common drive (0.47 ± 0.08 vs. 0.47 ± 0.06) did not change across conditions. The FCC signal was correlated with force (R = 0.45 ± 0.06), and the CoV for FCC increased in the painful condition (5.69 ± 1.29% vs. 7.83 ± 2.61%; P < 0.05). These results indicate that nociceptive stimulation increased the low-frequency variability in synaptic input to motoneurons. PMID:22049336

48 CFR 10.003 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MARKET RESEARCH 10.003 Contract clause. The contracting officer shall insert the clause at 52.210-1, Market Research, in solicitations and contracts over $5 million for the procurement of items other than...

NASA Glenn Research Center Support of the Advanced Stirling Radioisotope Generator Project

NASA Technical Reports Server (NTRS)

Wilson, Scott D.; Wong, Wayne A.

2015-01-01

A high-efficiency radioisotope power system was being developed for long-duration NASA space science missions. The U.S. Department of Energy (DOE) managed a flight contract with Lockheed Martin Space Systems Company to build Advanced Stirling Radioisotope Generators (ASRGs), with support from NASA Glenn Research Center. DOE initiated termination of that contract in late 2013, primarily due to budget constraints. Sunpower, Inc., held two parallel contracts to produce Advanced Stirling Convertors (ASCs), one with Lockheed Martin to produce ASC-F flight units, and one with Glenn for the production of ASC-E3 engineering unit "pathfinders" that are built to the flight design. In support of those contracts, Glenn provided testing, materials expertise, Government-furnished equipment, inspection capabilities, and related data products to Lockheed Martin and Sunpower. The technical support included material evaluations, component tests, convertor characterization, and technology transfer. Material evaluations and component tests were performed on various ASC components in order to assess potential life-limiting mechanisms and provide data for reliability models. Convertor level tests were conducted to characterize performance under operating conditions that are representative of various mission conditions. Despite termination of the ASRG flight development contract, NASA continues to recognize the importance of high-efficiency ASC power conversion for Radioisotope Power Systems (RPS) and continues investment in the technology, including the continuation of the ASC-E3 contract. This paper describes key Government support for the ASRG project and future tests to be used to provide data for ongoing reliability assessments.

[The contracting process and outsourcing in health: the scenario for dispute between public and private interests].

PubMed

Albuquerque, Maria do Socorro Veloso; Morais, Heloísa Maria Mendonça de; Lima, Luci Praciano

2015-06-01

This research analyzed the public-private composition in the municipal health network and aspects of the contracting/outsourcing process for services over the period from 2001 to 2008. The research method used was a case study with documentary research and interviews. The interviewees were former secretaries of health, directors of regulation and district managers. The categories of analysis used were public funds, care networks and public control. The results showed that the contracting was restricted to philanthropic units. With respect to the other private establishments linked to the public care network, non-compliance with programmatic aspects was detected, such as the lack of regulation of bidding processes required for contracting. Management authorities did not actively pursue building up state public services, or the formation of care networks. The contracted establishments conducted their activities without effective external and internal control mechanisms, which are paramount for the proper use of public resources. The authors conclude that the contracting process does not significantly alter the standard of buying and selling of services and indeed does not enhance the empowering process of the role of the public domain.

Guiding the United States Government Response to an Overseas Chemical, Biological, Radiological, or Nuclear Disaster

DTIC Science & Technology

2001-02-01

NUCLEAR DISASTER by Roman N. Hrycaj, Colonel, USAF A Research Report Submitted to the Faculty In Partial Fulfillment of the Graduation Requirements... Nuclear Disaster Contract Number Grant Number Program Element Number Author(s) Hrycaj, Roman N. Project Number Task Number Work Unit Number

Graduate Course Contract Law Deskbook (54th). Volume 2

DTIC Science & Technology

2005-01-01

GRADUATE COURSE THE FIFTY-FOURTH CONTRACT LAW DESKBOOK Contract and Fiscal Law Department The Judge Advocate General’s School, United States Army...OF ABSTRACT 8. 54th GC Contract Law Deskbook, Volume II, Fall 2005 1. AGENCY USE ONLY (Leave blank) 4. TITLE AND SUBTITLE 54th Graduate...Louisiana, 1998-1999; Contract Law Attorney, and Chief, Administrative Law, Office of the Staff Judge Advocate, Fort Polk, Louisiana, 1996-1998. Member

Processing Multiyear Procurement (MYP) Submissions - A Handbook for Air Force Program Offices

DTIC Science & Technology

1985-05-01

Contracting and Manufacturing Policy; "Policy Letter 84-1l - Multiyear Contracting Guidance" Headquarters, United States Air Force, Washington, D.C...supplement to Air Force FAR Sup No. 17.191: as enclosed in Thomas E. Lloyd, Colonel, USAF, Assistant DCS/Contracting , and Manufacturing , "DCS...Contracting and Manufacturing Policy Letter 84-16, Multiyear Contracting Guidance." Headquarters, Air Force Systems Command, Andrew Air Force Base

Integrated Genomic Biomarkers to Identify Aggressive Disease in African Americans with Prostate Cancer

DTIC Science & Technology

2017-09-01

Cancer” PRINCIPAL INVESTIGATOR: Dr. Albert Levin CONTRACTING ORGANIZATION: Henry Ford Health System Detroit, MI 48202 REPORT DATE: September 2017 TYPE...hfhs.org 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Henry Ford Health System 1...at Henry Ford Health System (HFHS) lists of eligible prostatectomy patients as defined in the Research Strategy, confirm availability of banked

Oil and Hazardous Materials Spill Response Technology Development, Strategic Plan

DTIC Science & Technology

2012-05-01

the pollutant can be recovered, burned, or dispersed . Objectives:  Develop the means to divert and contain sinking and suspended oils in order to...Research and Development Center 1 Chelsea Street New London, CT 06320 10. Work Unit No. (TRAIS) 11. Contract or Grant No. 12...similar analysis of prevention efforts should be carried out in the future. 17. Key Words oil, hazardous material, oil spill, pollution

23 CFR 635.115 - Agreement estimate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Agreement estimate. 635.115 Section 635.115 Highways... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.115 Agreement estimate. (a) Following the award of contract, an agreement estimate based on the contract unit prices and estimated quantities shall be...

NASA Glenn Research Center Support of the ASRG Project

NASA Technical Reports Server (NTRS)

Wilson, Scott D.; Wong, Wayne A.

2014-01-01

A high efficiency radioisotope power system is being developed for long-duration NASA space science missions. The U.S. Department of Energy (DOE) managed a flight contract with Lockheed Martin Space Systems Company (LMSSC) to build Advanced Stirling Radioisotope Generators (ASRGs), with support from NASA Glenn Research Center (GRC). Sunpower Inc. held two parallel contracts to produce Advanced Stirling Convertors (ASCs), one with DOELockheed Martin to produce ASC-F flight units, and one with GRC for the production of ASC-E3 engineering unit pathfinders that are built to the flight design. In support of those contracts, GRC provided testing, materials expertise, government furnished equipment, inspections, and related data products to DOELockheed Martin and Sunpower. The technical support includes material evaluations, component tests, convertor characterization, and technology transfer. Material evaluations and component tests have been performed on various ASC components in order to assess potential life-limiting mechanisms and provide data for reliability models. Convertor level tests have been used to characterize performance under operating conditions that are representative of various mission conditions. Technology transfers enhanced contractor capabilities for specialized production processes and tests. Despite termination of flight ASRG contract, NASA continues to develop the high efficiency ASC conversion technology under the ASC-E3 contract. This paper describes key government furnished services performed for ASRG and future tests used to provide data for ongoing reliability assessments.

Effect of pain on the modulation in discharge rate of sternocleidomastoid motor units with force direction.

PubMed

Falla, Deborah; Lindstrøm, Rene; Rechter, Lotte; Farina, Dario

2010-05-01

To compare the behavior of sternocleidomastoid motor units of patients with chronic neck pain and healthy controls. Nine women (age, 40.4+/-3.5 yr) with chronic neck pain and nine age- and gender-matched healthy controls participated. Surface and intramuscular EMG were recorded from the sternocleidomastoid muscle bilaterally as subjects performed isometric contractions of 10-s duration in the horizontal plane at a force of 15 N in eight directions (0-360 degrees ; 45 degrees intervals) and isometric contractions at 15 and 30 N force with continuous change in force direction in the range 0-360 degrees . Motor unit behavior was monitored during the 10-s contractions and the subsequent resting periods. The mean motor unit discharge rate depended on the direction of force in the control subjects (P<0.05) but not in the patients. Moreover, in three of the nine patients, but in none of the controls, single motor unit activity continued for 8.1+/-6.1s upon completion of the contraction. The surface EMG amplitude during the circular contraction at 15N was greater for the patients (43.5+/-54.2 microV) compared to controls (16.9+/-14.9 microV; P<0.05). The modulation in discharge rate of individual motor units with force direction is reduced in the sternocleidomastoid muscle in patients with neck pain, with some patients showing prolonged motor unit activity when they were instructed to rest. These observations suggest that chronic neck pain affects the change in neural drive to muscles with force direction. Copyright 2009 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

48 CFR 22.406-9 - Withholding from or suspension of contract payments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... damages due the United States under the Contract Work Hours and Safety Standards Act. (See 22.302.) (1) If... the same prime contractor that is subject to either Davis-Bacon Act or Contract Work Hours and Safety... Withholdings Under the Davis-Bacon Act (40 U.S.C. 276(a)) and/or Contract Work Hours and Safety Standards Act...

International Conference on Curves and Surfaces (4th), Saint-Malo, France, 1-7 July 1999. Proceedings, Volume 1. Curve and Surface Design

DTIC Science & Technology

2000-04-01

the Air Force grant issued by the European Aerospace Office of Research and Development. The United States has a royalty free license throughout the...UNIVERSITY PRESS Nashville fl9 ~Oc -O i U.S. Government Rights License This work relates to Department of the Air Force Grant/rContract issued by the...in engineering , medicine, and the sciences. SERIES EDITOR: Larry L. Schumaker Stevenson Professor of Mathematics Vanderbilt University PREVIOUSLY

Procurement Ethics: Have We Resolved the Army’s Expeditionary Contracting Problems?

DTIC Science & Technology

2011-03-11

Distribution A: Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT The United States Army discovered numerous occurrences of unethical behavior by...The United States Army discovered numerous occurrences of unethical behavior by contracting officials and contractors while providing contracting...ARMY’S EXPEDITIONARY CONTRACTING PROBLEMS? The United States Army discovered numerous occurrences of unethical behavior by contracting officials

Research on air and missile defense task allocation based on extended contract net protocol

NASA Astrophysics Data System (ADS)

Zhang, Yunzhi; Wang, Gang

2017-10-01

Based on the background of air and missile defense distributed element corporative engagement, the interception task allocation problem of multiple weapon units with multiple targets under network condition is analyzed. Firstly, a mathematical model of task allocation is established by combat task decomposition. Secondly, the initialization assignment based on auction contract and the adjustment allocation scheme based on swap contract were introduced to the task allocation. Finally, through the simulation calculation of typical situation, the model can be used to solve the task allocation problem in complex combat environment.

75 FR 64642 - Indexed Annuities

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-20

... under the Securities Act of 1933, which defines the terms ``annuity contract'' and ``optional annuity contract'' under the Act. On July 12, 2010, the United States Court of Appeals for the District of Columbia... under the Securities Act of 1933.\\1\\ Rule 151A defines the terms ``annuity contract'' and ``optional...

41 CFR 50-201.1202 - Complaints.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of, or...

41 CFR 50-201.1202 - Complaints.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of, or...

41 CFR 50-201.1202 - Complaints.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of, or...

41 CFR 50-201.1202 - Complaints.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of, or...

41 CFR 50-201.1202 - Complaints.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of, or...

Preceding muscle activity influences motor unit discharge and rate of torque development during ballistic contractions in humans

PubMed Central

Van Cutsem, Michaël; Duchateau, Jacques

2005-01-01

To investigate the effect of initial conditions on the modulation of motor unit discharge during fast voluntary contractions, we compared ballistic isometric contractions of the ankle dorsiflexor muscles that were produced from either a resting state or superimposed on a sustained contraction. The torque of the dorsiflexors and the surface and intramuscular EMGs from the tibialis anterior were recorded. The results showed that the performance of a ballistic contraction from a sustained contraction (∼25% maximal voluntary contraction (MVC)) had a negative effect on the maximal rate of torque development. Although the electromechanical delay was shortened, the EMG activity during the ballistic contraction was less synchronized. These observations were associated with a significant decline in the average discharge rate of single motor units (89.8 ± 3.8 versus 115 ± 5.8 Hz) and in the percentage of units (6.2 versus 15.5% of the whole sample) that exhibited double discharges at brief intervals (= 5 ms). High-threshold units that were not recruited during the sustained contraction displayed the same activation pattern, which indicates that the mechanisms responsible for the decline in discharge rate were not restricted to previously activated units, but appear to influence the entire motor unit pool. When a premotor silent period (SP) was observed at the transition from the sustained muscular activity to the ballistic contraction (19% of the trials), these adjustments in motor unit activity were not present, and the ballistic contractions were similar to those performed from a resting state. Together, these results indicate that initial conditions can influence the capacity for motor unit discharge rate and hence the performance of a fast voluntary contraction. PMID:15539402

Developing and Managing University-Industry Research Collaborations through a Process Methodology/Industrial Sector Approach

ERIC Educational Resources Information Center

Philbin, Simon P.

2010-01-01

A management framework has been successfully utilized at Imperial College London in the United Kingdom to improve the process for developing and managing university-industry research collaborations. The framework has been part of a systematic approach to increase the level of research contracts from industrial sources, to strengthen the…

Using Technology to Support the Army Learning Model

DTIC Science & Technology

2016-02-01

Jessie Hyland ICF International Jennifer S. Tucker Steve Burnett U.S. Army Research Institute February 2016 United States...Director Research accomplished under contract for the Department of the Army by ICF International Technical Review by Jean Dyer...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) ICF International U. S. Army Research Institute 9300 Lee Highway

Required Security Screenings for Researchers: A Policy Analysis and Commentary

ERIC Educational Resources Information Center

Zucker, Andrew A.

2011-01-01

After the attacks of 9/11/2001 the federal government implemented new policies intended to protect people and institutions in the United States. A surprising policy requires education researchers conducting research under contract to the U.S. Department of Education (ED) to obtain security clearances, sometimes known as security screenings.…

Effective Measures of Continuing Education

DTIC Science & Technology

2013-03-01

with increased participation in charitable or public service activities. The percentage of people who donate their time to organizations and the... Effective Measures of Continuing Education by Colonel Morris A. Turner United States Army United...STRATEGY RESEARCH PROJECT .33 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Effective Measures of Continuing Education 5a. CONTRACT

NASA work unit system users manual

NASA Technical Reports Server (NTRS)

1972-01-01

The NASA Work Unit System is a management information system for research tasks (i.e., work units) performed under NASA grants and contracts. It supplies profiles to indicate how much effort is being expended to what types of research, where the effort is being expended, and how funds are being distributed. The user obtains information by entering requests on the keyboard of a time-sharing terminal. Responses are received as video displays or typed messages at the terminal, or as lists printed in the computer room for subsequent delivery by messenger.

Development of Medical Technology for Contingency Response to Marrow Toxic Agents

DTIC Science & Technology

2013-04-29

Period 1 5a. CONTRACT NUMBER N/A 5b. GRANT NUMBER N00014-13-1-0039 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR( S ) Spellman, Stephen 5d. PROJECT...NUMBER N/A 5e. TASK NUMBER Project 1, 2, 3, 4 5f. WORK UNIT NUMBER N/A 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) National Marrow Donor... S ) AND ADDRESS(ES) Office of Naval Research 875 N. Randolph St. Arlington, VA 22203 10. SPONSOR/MONITOR’S ACRONYM( S ) ONR 11. SPONSORING/MONITORING

Progress Report for the Joint Services Electronics Program

DTIC Science & Technology

1988-06-30

31, 1988. The current JSEP contract that began on October 1, 1986. contains 22 work units (Unit 3 of the new contract was withdrawn and Unit 6 S, has...Professor Bang-Sup Song has joined the VLSI Circuits Group. Although none of these young faculty is currently receiving direct support from the JSEP...deposition. (2) We have in’,.estgated the use of lc\\%-energy primary and secondary accelerated-ion doping during MBE * grov tn to demonstrate increa-es in

9 CFR 206.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.1 Definitions. The definitions... and packer rights and obligations under the contract. Base price. The price paid for swine before the application of any premiums or discounts, expressed in dollars per unit. Boar. A sexually-intact male swine...

9 CFR 206.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.1 Definitions. The definitions... and packer rights and obligations under the contract. Base price. The price paid for swine before the application of any premiums or discounts, expressed in dollars per unit. Boar. A sexually-intact male swine...

9 CFR 206.1 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.1 Definitions. The definitions... and packer rights and obligations under the contract. Base price. The price paid for swine before the application of any premiums or discounts, expressed in dollars per unit. Boar. A sexually-intact male swine...

9 CFR 206.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE SWINE CONTRACT LIBRARY § 206.1 Definitions. The definitions... and packer rights and obligations under the contract. Base price. The price paid for swine before the application of any premiums or discounts, expressed in dollars per unit. Boar. A sexually-intact male swine...

An Innovation for Global Clean Water

NASA Technical Reports Server (NTRS)

1995-01-01

Under contract to NASA, Umpqua Research developed the Microbial Check Valve (MCV) iodine-dispensing system for the Space Shuttle Orbiter, introduced in 1979 to purify astronauts' drinking water. In 1989, NASA awarded the company a new contract to develop a system for continuous iodine release over long periods for use in the International Space Station. In 1993, the company demonstrated the Regenerable Biocide Delivery Unit, and NASA granted it an exclusive license.

Hybrid Vapor Compression Ejector Cycle: Presentation to IAPG Mechanical Working Group

DTIC Science & Technology

2011-08-01

Compression Ejector Cycle: Presentation to IAPG Mechanical Working Group Parmesh Verma and Tom Radcliff, United Technologies Research Center UNCLASSIFIED... Ejector Cycle Presentation to IAPG Mechanical Working Group 5a. CONTRACT NUMBER W909MY-10-C-0005 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...hybrid vapor compression ejector heat pump cycle developed under an American Recovery and Reinvestment Act funded contract is provided. 15. SUBJECT

Motor unit activity when young and old adults perform steady contractions while supporting an inertial load

PubMed Central

Gould, Jeffrey R.; Enoka, Roger M.

2013-01-01

The purpose of the study was to compare the discharge characteristics of biceps brachii motor units of young and old adults when they performed steady, submaximal contractions while the arm supported different inertial loads. Young (28 ± 4 yr; n = 16) and old (75 ± 4 yr; n = 14) adults performed steady contractions with the elbow flexors at target forces set at either small (11.7 ± 4.4% maximum) or large (17.8 ± 6.5% maximum) differences below the recruitment threshold force of the motor unit (n = 40). The task was to maintain an elbow angle at 1.57 rad until the motor unit was recruited and discharged action potentials for ∼120 s. Time to recruitment was longer for the larger target force difference (187 ± 227 s vs. 23 ± 46 s, P < 0.001). Once recruited, motor units discharged action potentials either repetitively or intermittently, with a greater proportion of motor units exhibiting the repetitive pattern for old adults. Discharge rate at recruitment and during the steady contraction was similar for the two target force differences for old adults but was greater for the small target force difference for young adults. Discharge variability was similar at recruitment for the two age groups but less for the old adults during the steady contraction. The greatest difference between the present results and those reported previously when the arm pulled against a rigid restraint was that old adults modulated discharge rate less than young adults across the two contraction intensities for both load types. PMID:23221403

Coordinating ‘Ethical’ Clinical Trials: The Role of Research Coordinators in the Contract Research Industry

PubMed Central

Fisher, Jill A.

2010-01-01

Change in the way new drugs are developed, including the privatization of clinical trials, has altered the arrangement and roles of health care professions. In this article I examine one aspect of this change: the role of research coordinators in the conduct of contract research in the United States. My focus on coordinators highlights the ethical conflicts embedded in clinical trials. I describe the ways in which coordinators experience and contend with the conflict between research and care and show how their construction of ethics is distinct from institutional conceptions formally associated with human subjects research. My analysis demonstrates how the coordinators' focus on ethics is a response to their role conflict and an attempt to reinsert individualized care into the context of research. PMID:17184412

Line Parameters Of CH3CN From 305 To 415 cm-1

NASA Astrophysics Data System (ADS)

Brown, Linda R.; Kamadjeu, D. A.; Kleiner, I.; Orphal, J.; Sams, R. L.

2006-12-01

Mapping important compounds, such as hydrocarbons and nitriles, is needed in order to understand the photochemical cycle of Titan and how it couples with the dynamics to produce organic aerosols. For this, the CIRS spectrometer (Composite Infrared Spectrometer) on board Cassini is currently recording rotation and vibration-rotation spectra of Titan between 10 and 1400 cm-1. To support analysis of these data, high resolution laboratory spectra of CH3CN have been recorded using Fourier transform spectrometers at PNL and LISA. This paper presents a prediction of line positions and intensities of CH3 CN for the ν&8 fundamental and the 2ν8 -ν8 hot band (located near 360 cm&-1). Analyses of the two fundamentals near 10 microns are in progress. Part of the research described in this paper was performed at the Jet Propulsion Laboratory, California Institute of Technology, under contract with The National Aeronautics and Space Administration. I.K, J. O and A. D. also want to thank the Programme National de Planétologie for funding part of this research. This research was supported, in part, by the United States Department of Energy, Office of Basic Energy Sciences, Chemical Sciences Division and the experimental part was performed at the W. R, Wiley Environmental Molecular Science Laboratory, a national scientific user facility sponsored by the Department of Energy's Office of Biological and Environmental Research located at the Pacific Northwest National Laboratory. Pacific Northwest National Laboratory is operated for the United States Department of Energy by Battelle under contract DE-AC06-76RLO 1830. We wish to thank Drs R. Antilla and S. Alanko for kindly making available supplemental data in electronic and paper forms. #

Preliminary design of 1 kW bipolar Ni-MH battery for LEO-satellite application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, J.H.; Reisner, D.E.; Klein, M.G.

1996-12-31

Electro Energy, Inc. (EEI) is developing a bipolar nickel-metal hydride rechargeable battery based upon the use of stackable wafer cells. The key to viable bipolar operation has been this unique modular (unitized) approach. The patented unit wafer-cell construct exploits the chemical and thermal properties of a proprietary electrically conductive plastic film. Characteristic of bipolar batteries, current flows across the cell interfaces-perpendicular to the electrode plane. EEI has recently contracted with NASA Lewis Research Center (LeRC) to develop an optimized design 1 kW flightweight battery, for low-earth-orbit (LEO) satellite applications, over a 4-year period with a deliverable flightweight design package. Themore » contract includes an option for EEI to deliver up to three flight quality batteries in an 18-month follow-on program. NASA LeRC has promulgated that the program steps include the design, fabrication, and evaluation of four evolutionary stages of the final battery design which have been designated Preliminary, Improved, Optimized, and Flightweight Design. Initial results from the Preliminary Stage are presented including a 1 kW battery design, thermal design, parameter study, and component development in subscale bipolar batteries.« less

A Characterization of an Element of Best Simultaneous Approximation.

DTIC Science & Technology

1983-09-01

space Work Unit Number 3 - Numerical Analysis and Scientific Computing C . R. Category: G.1.2 * Department of Mathematics, Lewis and Clark College...Portland, OR 97219, USA. Sponsored by the United States Army under Contract No. DAAG29-80- C -0041. - ,1I K SIGNIFICANCE AND EXPLANATION A basic problem of...under Contract No. DAAG29-80- C -0041. others, e.g. Goel et.al. [8], ltilman (14], and Phillips et.al. [15], give characterizations in terms of one or

77 FR 44045 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-60; Introduction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

... the United States Defense Advanced Research Projects Agency (DARPA) to the list of agencies that have... taxation of Government cost-reimbursement contracts when contractors and their subcontractors purchase...

48 CFR 970.5235-1 - Federally funded research and development center sponsoring agreement.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Solicitation Provisions and Contract Clauses for Management and Operating Contracts 970.5235-1... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Federally funded research...

Critical Life Prediction Research on Boron-Enhanced Ti-6A1-4V

DTIC Science & Technology

2007-05-01

2.4 High Modulus Ti-6Al-2Fe-0.1Si-0.6B “T” Extrusions for HSCT program. Ref. Government Contract No. NASI -20220: High Speed Research-Airframe...0.1Si-0.6B “T” Extrusions for HSCT program. Ref. Government Contract No. NASI -20220: High Speed Research-Airframe Technology report. with the focus...baseline Ti-6Al-4V (Government Contract No. NASI -20220, High Speed Research-Airframe Technology Report, 1997: 3-5, 14, 26). 1 in 3 in 16 In

Centennial Changes in Surgical Care and Research

DTIC Science & Technology

2000-09-01

5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Pruitt, B. A., Jr. 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT...NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) United States Army Institute of Surgical Research, JBSA Fort Sam Houston, TX 78234 8...PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S

48 CFR 35.014 - Government property and title.

Code of Federal Regulations, 2011 CFR

2011-10-01

... basic or applied scientific research, apply to contracts with nonprofit institutions of higher education and nonprofit organizations whose primary purpose is the conduct of scientific research: (1) If the... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.014 Government property and...

Motor unit recruitment and derecruitment induced by brief increase in contraction amplitude of the human trapezius muscle

PubMed Central

Westad, C; Westgaard, R H; De Luca, C J

2003-01-01

The activity pattern of low-threshold human trapezius motor units was examined in response to brief, voluntary increases in contraction amplitude (‘EMG pulse’) superimposed on a constant contraction at 4–7% of the surface electromyographic (EMG) response at maximal voluntary contraction (4–7% EMGmax). EMG pulses at 15–20% EMGmax were superimposed every minute on contractions of 5, 10, or 30 min duration. A quadrifilar fine-wire electrode recorded single motor unit activity and a surface electrode recorded simultaneously the surface EMG signal. Low-threshold motor units recruited at the start of the contraction were observed to stop firing while motor units of higher recruitment threshold stayed active. Derecruitment of a motor unit coincided with the end of an EMG pulse. The lowest-threshold motor units showed only brief silent periods. Some motor units with recruitment threshold up to 5% EMGmax higher than the constant contraction level were recruited during an EMG pulse and kept firing throughout the contraction. Following an EMG pulse, there was a marked reduction in motor unit firing rates upon return of the surface EMG signal to the constant contraction level, outlasting the EMG pulse by 4 s on average. The reduction in firing rates may serve as a trigger to induce derecruitment. We speculate that the silent periods following derecruitment may be due to deactivation of non-inactivating inward current (‘plateau potentials’). The firing behaviour of trapezius motor units in these experiments may thus illustrate a mechanism and a control strategy to reduce fatigue of motor units with sustained activity patterns. PMID:14561844

Comparison of contraction times of a muscle and its motor units

NASA Technical Reports Server (NTRS)

Eldred, E.; Smith, L.; Edgerton, V. R.

1992-01-01

The twitch contraction time (CT) for each of 13 soleus (SOL) and 13 medial gastrocnemius (MG) muscles was compared with the mean CT from a sample of its motor units (MUs; 356 total) to see if the CT of a whole muscle when tested at its optimal length (Lo) differed systematically from that of its MUs tested at their individual Lo's. The CTs of the whole muscle were significantly longer in the ratio of 1.13. This is consistent with a hypothesis that electrical-field effects result in a more protracted contraction of the individual muscle fiber.

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

48 CFR 9903.202-1 - General requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... any small business concern. (b) Completed Disclosure Statements are required in the following circumstances: (1) Any business unit that is selected to receive a CAS-covered contract or subcontract of $50... the first CAS-covered contract is received within 90 days of the start of the cost accounting period...

48 CFR 9903.201-2 - Types of CAS coverage.

Code of Federal Regulations, 2012 CFR

2012-10-01

... later award of a CAS-covered contract. Full coverage applies to contractor business units that— (1) Receive a single CAS-covered contract award of $50 million or more; or (2) Received $50 million or more in net CAS-covered awards during its preceding cost accounting period. (b) Modified coverage. (1...

48 CFR 9903.201-2 - Types of CAS coverage.

Code of Federal Regulations, 2014 CFR

2014-10-01

... later award of a CAS-covered contract. Full coverage applies to contractor business units that— (1) Receive a single CAS-covered contract award of $50 million or more; or (2) Received $50 million or more in net CAS-covered awards during its preceding cost accounting period. (b) Modified coverage. (1...

75 FR 5716 - Federal Acquisition Regulation; FAR Case 2008-024, Inflation Adjustment of Acquisition-Related...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-04

... Consumer Price Index for all urban consumers, except for Davis-Bacon Act, Service Contract Act, and trade... consumers, except for Davis-Bacon Act, Service Contract Act, and trade agreements thresholds (see FAR 1.109... acquisition-related thresholds established by the Davis-Bacon Act, the Service Contract Act, or the United...

Porous Electrodes I: Numerical Simulation Using Random Network and Single Pore Models.

DTIC Science & Technology

1984-01-31

characteristic of Zn and ZnO ) and scaling them down to the magnitude of a unit pore size- approximately 10i in diameter. We define a characteristic...supported by the Office of Naval Research under contract N00014-81-K-0339. 11 - 15 - REFERENCES 1. R. de Levis in Advances in Electrochemistry and...P. 3. Hendra Dr. C. E. Mueller Department of Chemistry The Electrochemistry Branch University of Southampton Naval Surface Weapons Center

Military Health Behaviors: Promotion of Healthy Weight and Fitness in Career Personnel

DTIC Science & Technology

2006-05-01

Lolita M. Burrell, Ph.D. CONTRACTING ORGANIZATION: Pennington Biomedical Research Center 6400 Perkins Rd. Baton Rouge, LA 70808-4124...FADA, and MAJ Lolita M. Burrell, Ph.D 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING...Website Launch Plan: 1) July 24th: WAMC and Ft. Bragg “Media Blitz” - Interview with Paraglide, WAMC PAO - Photo -op with WAMC and Ft. Bragg VIPS

Atlas/Data Abstract for the United States and Selected Areas. Fiscal Year 1989

DTIC Science & Technology

1989-01-01

are generally reported at the i t where the work is performed. For example. if a con :ac or located in Nevada and wins a construction )ot! in Utah, tl...0 4l?~.5 1’".t� Service Contracts 24. j𔃾. . 1 , :of,;t) j , 467, 4X Construction Contrac.ts 3, f5’ Ś). 12,tf.;9" Z3),t); 6,:16 Civil Function...Contracts 237,277 58,434 22,106 148,375 8,362 Construction Contracts 162,202 113,971 48,231 0 0 Civil Function Contracts 17,458 17,458 0 0 0

48 CFR 252.225-7006 - Quarterly reporting of actual contract performance outside the United States.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Director of Defense Procurement and Acquisition Policy (Contract Policy and International Contracting... actual contract performance outside the United States. 252.225-7006 Section 252.225-7006 Federal... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7006 Quarterly reporting of...

48 CFR 252.225-7006 - Quarterly reporting of actual contract performance outside the United States.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Director of Defense Procurement and Acquisition Policy (Contract Policy and International Contracting... actual contract performance outside the United States. 252.225-7006 Section 252.225-7006 Federal... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7006 Quarterly reporting of...

Neural control of muscle force: indications from a simulation model

PubMed Central

Luca, Carlo J. De

2013-01-01

We developed a model to investigate the influence of the muscle force twitch on the simulated firing behavior of motoneurons and muscle force production during voluntary isometric contractions. The input consists of an excitatory signal common to all the motor units in the pool of a muscle, consistent with the “common drive” property. Motor units respond with a hierarchically structured firing behavior wherein at any time and force, firing rates are inversely proportional to recruitment threshold, as described by the “onion skin” property. Time- and force-dependent changes in muscle force production are introduced by varying the motor unit force twitches as a function of time or by varying the number of active motor units. A force feedback adjusts the input excitation, maintaining the simulated force at a target level. The simulations replicate motor unit behavior characteristics similar to those reported in previous empirical studies of sustained contractions: 1) the initial decrease and subsequent increase of firing rates, 2) the derecruitment and recruitment of motor units throughout sustained contractions, and 3) the continual increase in the force fluctuation caused by the progressive recruitment of larger motor units. The model cautions the use of motor unit behavior at recruitment and derecruitment without consideration of changes in the muscle force generation capacity. It describes an alternative mechanism for the reserve capacity of motor units to generate extraordinary force. It supports the hypothesis that the control of motoneurons remains invariant during force-varying and sustained isometric contractions. PMID:23236008

Process for fractionating fast-pyrolysis oils, and products derived therefrom

DOEpatents

Chum, Helena L.; Black, Stuart K.

1990-01-01

A process is disclosed for fractionating lignocellulosic materials fast-prolysis oils to produce phenol-containing compositions suitable for the manufacture of phenol-formaldehyde resins. The process includes admixing the oils with an organic solvent having at least a moderate solubility parameter and good hydrogen The United States Government has rights in this invention under Contract No. DE-AC02-83CH10093 between the United States Department of Energy and the Solar Energy Research Institute, a Division of the Midwest Research Institute.

Assessment of Two Desk-Top Computer Simulations Used to Train Tactical Decision Making (TDM) of Small Unit Infantry Leaders

DTIC Science & Technology

2007-04-01

judgmental self-doubt, depression, and causal uncertainty, tend to take fewer risks, and have lower self-esteem. Results from two studies (Nygren, 2000...U.S. Army Research Institute for the Behavioral and Social Sciences Research Report 1869 Assessment of Two Desk-Top Computer Simulations Used to...SUBTITLE 5a. CONTRACT OR GRANT NUMBER Assessment of Two Desk-Top Computer Simulations Used to Train Tactical Decision Making (TDM) of Small Unit

29 CFR 4.112 - Contracts to furnish services “in the United States.”

Code of Federal Regulations, 2010 CFR

2010-07-01

... Application of the McNamara-O'Hara Service Contract Act Covered Contracts Generally § 4.112 Contracts to furnish services “in the United States.” (a) The Act and the provisions of this part apply to contract... Act. (b) A service contract to be performed in its entirety outside the geographical limits of the...

Idaho Transportation Department 2016 Customer Communication Survey

DOT National Transportation Integrated Search

2017-06-23

In 2016, the Idaho Transportation Department contracted with the University of Idaho's Social Science Research Unit to conduct a survey on the general public's engagement and communication with the department. The goal of conducting this survey was t...

45 CFR 73.735-1003 - Conflicts of interest statutes.

Code of Federal Regulations, 2012 CFR

2012-10-01

... sections 203, 205, 207 and 208 of title 18, United States Code, all of which carry criminal penalties... be possible to achieve where, for example, a consultant has an executive position with his or her... formulate a research and development contract or a research grant, and for the same reason, it is in the...

Molecular Mechanisms Underlying Individual Differences in Response to Stress in a Previously Validated Animal Model of PTSD

DTIC Science & Technology

2012-04-01

CONTRACTING ORGANIZATION: Bronx Veterans Medical Research Foundation, Inc... Bronx , NY 10468-3904 REPORT DATE: April 2012 TYPE OF REPORT: Final PREPARED FOR: U.S. Army...WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Bronx Veterans Medical Research

Summary of Research on Education and the Rural-Urban Transformation. Final Report.

ERIC Educational Resources Information Center

Textor, Robert B.; And Others

This monograph is the summary report of the "Education and the Rural-Urban Transformation" (ERUT) portion of the United States Office of Education research contract concerning "Content and Instructional Methods of Education for the Economic-Political-Social Development of Nations." The ERUT team conducted a continuing seminar throughout the…

Synthesis of 1,3-Dinitrohexahydropyrimidine via Ring Contraction of Ether-Linked Nitramines

DTIC Science & Technology

2016-07-01

ARL-TR-7706 ● JULY 2016 US Army Research Laboratory Synthesis of 1,3-Dinitrohexahydropyrimidine via Ring Contraction of Ether...JULY 2016 US Army Research Laboratory Synthesis of 1,3-Dinitrohexahydropyrimidine via Ring Contraction of Ether-Linked Nitramines by...YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) July 2016 2. REPORT TYPE Final 3. DATES COVERED (From - To) Fiscal Year 2013 4. TITLE

Current challenges and realities for forest-based businesses adjacent to public lands in the United States

Treesearch

Emily J. Davis; Jesse Abrams; Eric M. White; Cassandra Moseley

2018-01-01

Through contracting and timber sales, the private sector is engaged in management of national forest lands and local community economies in the United States. But there is little recent research about current relationships between these lands and timber purchasers that could better inform future timber and biomass sale and business assistance policies and programs. We...

System Engineering and Integration Contract for Implementation of the National Airspace System Plan. Volume 2. Section 5.0 NAS Plan Project Findings.

DTIC Science & Technology

1984-08-01

and FPS-60 -’ vacuum-tube radars. There will be remote control interface units ( RCIU ) for tube-type radars, and an ARSR-3 relocation and RIH package...Facility RCE Remote Control Equipment; Radio Control Equipment RCIU Remote Control Interface Units RCO Remote Communications Outlet RDCC Research

The Effect of Toxic Leadership

DTIC Science & Technology

2012-03-15

traits) and not the disease (culture, climate, outcomes ).3 Several researchers agree that the long-term negative effect that toxic leaders have on an...The Effect of Toxic Leadership by Lieutenant Colonel Darrell W. Aubrey United States Army United States Army War...The Effect of Toxic Leadership 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Lieutenant

Motor unit recruitment during neuromuscular electrical stimulation: a critical appraisal.

PubMed

Bickel, C Scott; Gregory, Chris M; Dean, Jesse C

2011-10-01

Neuromuscular electrical stimulation (NMES) is commonly used in clinical settings to activate skeletal muscle in an effort to mimic voluntary contractions and enhance the rehabilitation of human skeletal muscles. It is also used as a tool in research to assess muscle performance and/or neuromuscular activation levels. However, there are fundamental differences between voluntary- and artificial-activation of motor units that need to be appreciated before NMES protocol design can be most effective. The unique effects of NMES have been attributed to several mechanisms, most notably, a reversal of the voluntary recruitment pattern that is known to occur during voluntary muscle contractions. This review outlines the assertion that electrical stimulation recruits motor units in a nonselective, spatially fixed, and temporally synchronous pattern. Additionally, it synthesizes the evidence that supports the contention that this recruitment pattern contributes to increased muscle fatigue when compared with voluntary actions and provides some commentary on the parameters of electrical stimulation as well as emerging technologies being developed to facilitate NMES implementation. A greater understanding of how electrical stimulation recruits motor units, as well as the benefits and limitations of its use, is highly relevant when using this tool for testing and training in rehabilitation, exercise, and/or research.

26 CFR 1.460-2 - Long-term manufacturing contracts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... time normally required to design and manufacture the first unit of an item for which the taxpayer... manufacture a new type of industrial equipment. C reasonably expects the normal production period for this... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Long-term manufacturing contracts. 1.460-2...

48 CFR 52.215-10 - Price Reduction for Defective Certified Cost or Pricing Data.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the data to the attention of the Contracting Officer. (iii) The contract was based on an agreement... shall pay the United States at the time such overpayment is repaid— (1) Interest compounded daily, as...

48 CFR 52.215-10 - Price Reduction for Defective Certified Cost or Pricing Data.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the data to the attention of the Contracting Officer. (iii) The contract was based on an agreement... shall pay the United States at the time such overpayment is repaid— (1) Interest compounded daily, as...

48 CFR 52.215-10 - Price Reduction for Defective Certified Cost or Pricing Data.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the data to the attention of the Contracting Officer. (iii) The contract was based on an agreement... shall pay the United States at the time such overpayment is repaid— (1) Interest compounded daily, as...

48 CFR 212.7002-1 - Contracts under the program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for Transition to Follow-On Contracting After Use of Other Transaction Authority 212.7002-1 Contracts under the program. (a) The contracting officer may use FAR part 12 procedures to award a contract for an... process begun as a prototype project under an other transaction agreement or as a research project carried...

A Female Urinary Diversion Device for Military Women in the Deployed Environment

DTIC Science & Technology

2016-10-27

9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) TriService Nursing Research TSNRP Program, 4301 Jones...reported there were many opportunities for a FUDD due to unsanitary and challenging conditions. Implications for Military Nursing : This research...Contract PoP: 6/1/2011 - 5/31/2016 Customer: TRISERVICE NURSING RESEARCH PROGRAM Customer Contract ID: HU0001 -11-1-TS02 Contract Manager: Robinson

8 CFR 233.4 - Preinspection outside the United States.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Preinspection outside the United States... CONTRACTS WITH TRANSPORTATION LINES § 233.4 Preinspection outside the United States. (a) Form I-425 agreements. A transportation line bringing applicants for admission to the United States through...

8 CFR 233.4 - Preinspection outside the United States.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Preinspection outside the United States... CONTRACTS WITH TRANSPORTATION LINES § 233.4 Preinspection outside the United States. (a) Form I-425 agreements. A transportation line bringing applicants for admission to the United States through...

Lens positioner with five degrees of freedom

DOEpatents

Kobierecki, Marian W.; Rienecker, Jr., Frederick

1978-01-01

A device for positioning lenses precisely with five degrees of freedom (three translations and two angular rotations). The unique features of the device are its compact design, large clear aperture, and high degree of positioning accuracy combined with five degrees of freedom in axis motion. Thus, the device provides precision and flexibility in positioning of optical components. BACKGROUND OF THE INVENTION The invention described herein was made in the course of, or under, Contract No. AT(29-1)-1183, with the United States Energy Research and Development Administration.

Effects of Intracortical Infusion of 6-Hydroxydopamine on the Response of Kitten Visual Cortex to Monocular Deprivation.

DTIC Science & Technology

1983-03-30

Research - Contract N00014-81-K-0136. 7.4 1% .4- b ,. Summary Between 4 and 10 weeks of age 10 normally reared kittens were bilaterally implanted with...projected with an ophthalmoscope and marked on a tangent screen at a distance of 114 cm. Single Unit Recording Tungsten-in-glass microelectrodes ( Levick ...quantitative measures of ocular dominance have been calculated. Binocularity ( B ), as defined by Pettigrew and Kasamatsu (1978). is the number of cells in ocular

Portable Android Dari and Pashto Soft Keyboard

DTIC Science & Technology

2013-08-01

with a collection of information if it does not display a currently valid OMB control number . PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1...Dari and Pashto Soft Keyboard 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Michael Lee 5d. PROJECT NUMBER R...0006163.9 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Army Research Laboratory ATTN: RDRL

24 CFR 891.565 - Term of HAP contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Term of HAP contract. 891.565... 8 Assistance § 891.565 Term of HAP contract. The term of the HAP contract for assisted units shall be 20 years. If the project is completed in stages, the term of the HAP contract for assisted units...

41 CFR 60-741.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS, EQUAL EMPLOYMENT OPPORTUNITY, DEPARTMENT OF LABOR 741... Programs of the United States Department of Labor, or his or her designee. (g) Disability—(1) The term... functions incidental to the actual construction. (2) Contracting agency means any department, agency...

31 CFR 560.520 - Exportation of agricultural commodities on contracts entered into prior to May 7, 1995.

Code of Federal Regulations, 2011 CFR

2011-07-01

... States to Iran of any agricultural commodity under an export sales contract are authorized, provided: (1... with the exportation of other agricultural articles from the United States to Iran that do not fall...

Hypersonic Technology for Military Application

DTIC Science & Technology

1989-04-14

United Kingdom , and Japan. All but one NASA Langley Research Center - the half dozen were built in the 1950s and "quiet supersonic tunnel". Present plans...NUMBERS PROGRAM PROJECT ITASK WORK UNIT ELEMENT NO. INO. INO. IACCESSION NO. Andrews AFE, ’-D 20330 n/ n/ Ia /I11. TITLE (Inciude Security...work under Contract No. F49620-87-C-0122 be.ween the United States Air Force and the National Academy of Sciences. Coopies of this repoit are available

48 CFR 1842.7002 - Travel outside of the United States.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Travel outside of the... AND SPACE ADMINISTRATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Additional NASA Contract Clauses 1842.7002 Travel outside of the United States. The contracting officer shall...

48 CFR 1842.7002 - Travel outside of the United States.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Travel outside of the... AND SPACE ADMINISTRATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Additional NASA Contract Clauses 1842.7002 Travel outside of the United States. The contracting officer shall...

48 CFR 1842.7002 - Travel outside of the United States.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Travel outside of the... AND SPACE ADMINISTRATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Additional NASA Contract Clauses 1842.7002 Travel outside of the United States. The contracting officer shall...

48 CFR 1842.7002 - Travel outside of the United States.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Travel outside of the... AND SPACE ADMINISTRATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Additional NASA Contract Clauses 1842.7002 Travel outside of the United States. The contracting officer shall...

48 CFR 1842.7002 - Travel outside of the United States.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Travel outside of the... AND SPACE ADMINISTRATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Additional NASA Contract Clauses 1842.7002 Travel outside of the United States. The contracting officer shall...

Fluctuations in isometric muscle force can be described by one linear projection of low-frequency components of motor unit discharge rates

PubMed Central

Negro, Francesco; Holobar, Aleš; Farina, Dario

2009-01-01

The aim of the study was to investigate the relation between linear transformations of motor unit discharge rates and muscle force. Intramuscular (wire electrodes) and high-density surface EMG (13 × 5 electrode grid) were recorded from the abductor digiti minimi muscle of eight healthy men during 60 s contractions at 5%, 7.5% and 10% of the maximal force. Spike trains of a total of 222 motor units were identified from the EMG recordings with decomposition algorithms. Principal component analysis of the smoothed motor unit discharge rates indicated that one component (first common component, FCC) described 44.2 ± 7.5% of the total variability of the smoothed discharge rates when computed over the entire contraction interval and 64.3 ± 10.2% of the variability when computed over 5 s intervals. When the FCC was computed from four or more motor units per contraction, it correlated with the force produced by the muscle (62.7 ± 10.1%) by a greater degree (P < 0.001) than the smoothed discharge rates of individual motor units (41.4 ± 7.8%). The correlation between FCC and the force signal increased up to 71.8 ± 13.1% when the duration and the shape of the smoothing window for discharge rates were similar to the average motor unit twitch force. Moreover, the coefficients of variation (CoV) for the force and for the FCC signal were correlated in all subjects (R2 range = 0.14–0.56; P < 0.05) whereas the CoV for force was correlated to the interspike interval variability in only one subject (R2= 0.12; P < 0.05). Similar results were further obtained from measures on the tibialis anterior muscle of an additional eight subjects during contractions at forces up to 20% of the maximal force (e.g. FCC explained 59.8 ± 11.0% of variability of the smoothed discharge rates). In conclusion, one signal captures most of the underlying variability of the low-frequency components of motor unit discharge rates and explains large part of the fluctuations in the motor output during isometric contractions. PMID:19840996

Fluctuations in isometric muscle force can be described by one linear projection of low-frequency components of motor unit discharge rates.

PubMed

Negro, Francesco; Holobar, Ales; Farina, Dario

2009-12-15

The aim of the study was to investigate the relation between linear transformations of motor unit discharge rates and muscle force. Intramuscular (wire electrodes) and high-density surface EMG (13 x 5 electrode grid) were recorded from the abductor digiti minimi muscle of eight healthy men during 60 s contractions at 5%, 7.5% and 10% of the maximal force. Spike trains of a total of 222 motor units were identified from the EMG recordings with decomposition algorithms. Principal component analysis of the smoothed motor unit discharge rates indicated that one component (first common component, FCC) described 44.2 +/- 7.5% of the total variability of the smoothed discharge rates when computed over the entire contraction interval and 64.3 +/- 10.2% of the variability when computed over 5 s intervals. When the FCC was computed from four or more motor units per contraction, it correlated with the force produced by the muscle (62.7 +/- 10.1%) by a greater degree (P < 0.001) than the smoothed discharge rates of individual motor units (41.4 +/- 7.8%). The correlation between FCC and the force signal increased up to 71.8 +/- 13.1% when the duration and the shape of the smoothing window for discharge rates were similar to the average motor unit twitch force. Moreover, the coefficients of variation (CoV) for the force and for the FCC signal were correlated in all subjects (R(2) range = 0.14-0.56; P < 0.05) whereas the CoV for force was correlated to the interspike interval variability in only one subject (R(2) = 0.12; P < 0.05). Similar results were further obtained from measures on the tibialis anterior muscle of an additional eight subjects during contractions at forces up to 20% of the maximal force (e.g. FCC explained 59.8 +/- 11.0% of variability of the smoothed discharge rates). In conclusion, one signal captures most of the underlying variability of the low-frequency components of motor unit discharge rates and explains large part of the fluctuations in the motor output during isometric contractions.

Boarding Team Communications Phase I: Product Development and Evaluation

DTIC Science & Technology

2007-05-01

U.S. Coast Guard Research and Development Center 1082 Shennecossett Road, Groton, CT 06340-6048 Report No. CG-D-04-2007 Template: Report Cover...Technical Director United States Coast Guard Research & Development Center 1082 Shennecossett Road Groton, CT 06340-6048 Template...Research and Development Center 11. Contract or Grant No. 1082 Shennecossett Road Fairfax, VA 22030 Groton, CT 06340-6048 13. Type of

Systemization of Secure Computation

DTIC Science & Technology

2015-11-01

STINFO COPY AIR FORCE RESEARCH LABORATORY INFORMATION DIRECTORATE AFRL-RI-RS-TR-2015-241  UNITED STATES AIR FORCE  ROME, NY 13441 AIR FORCE...any patented invention that may relate to them. This report is the result of contracted fundamental research deemed exempt from public affairs...ES) Air Force Research Laboratory/RITA DARPA 525 Brooks Road 675 North Randolph Street Rome NY 13441-4505 Arlington, VA 22203

Learning from contract change in primary care dentistry: A qualitative study of stakeholders in the north of England.

PubMed

Holmes, Richard D; Steele, Jimmy G; Donaldson, Cam; Exley, Catherine

2015-09-01

The aim of this research was to explore and synthesise learning from stakeholders (NHS dentists, commissioners and patients) approximately five years on from the introduction of a new NHS dental contract in England. The case study involved a purposive sample of stakeholders associated with a former NHS Primary Care Trust (PCT) in the north of England. Semi-structured interviews were conducted with 8 commissioners of NHS dental services and 5 NHS general dental practitioners. Three focus group meetings were held with 14 NHS dental patients. All focus groups and interviews were audio recorded and transcribed verbatim. The data were analysed using a framework approach. Four themes were identified: 'commissioners' views of managing local NHS dental services'; 'the risks of commissioning for patient access'; 'costs, contract currency and commissioning constraints'; and 'local decision-making and future priorities'. Commissioners reported that much of their time was spent managing existing contracts rather than commissioning services. Patients were unclear about the NHS dental charge bands and dentists strongly criticised the contract's target-driven approach which was centred upon them generating 'units of dental activity'. NHS commissioners remained relatively constrained in their abilities to reallocate dental resources amongst contracts. The national focus upon practitioners achieving their units of dental activity appeared to outweigh interest in the quality of dental care provided. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Learning from contract change in primary care dentistry: A qualitative study of stakeholders in the north of England

PubMed Central

Holmes, Richard D.; Steele, Jimmy G.; Donaldson, Cam; Exley, Catherine

2015-01-01

The aim of this research was to explore and synthesise learning from stakeholders (NHS dentists, commissioners and patients) approximately five years on from the introduction of a new NHS dental contract in England. The case study involved a purposive sample of stakeholders associated with a former NHS Primary Care Trust (PCT) in the north of England. Semi-structured interviews were conducted with 8 commissioners of NHS dental services and 5 NHS general dental practitioners. Three focus group meetings were held with 14 NHS dental patients. All focus groups and interviews were audio recorded and transcribed verbatim. The data were analysed using a framework approach. Four themes were identified: ‘commissioners’ views of managing local NHS dental services’; ‘the risks of commissioning for patient access’; ‘costs, contract currency and commissioning constraints’; and ‘local decision-making and future priorities’. Commissioners reported that much of their time was spent managing existing contracts rather than commissioning services. Patients were unclear about the NHS dental charge bands and dentists strongly criticised the contract's target-driven approach which was centred upon them generating ‘units of dental activity’. NHS commissioners remained relatively constrained in their abilities to reallocate dental resources amongst contracts. The national focus upon practitioners achieving their units of dental activity appeared to outweigh interest in the quality of dental care provided. PMID:25765782

Educational and Nonprofit Institutions Receiving Prime Contract Awards for RDT&E (Research, Development, Test and Evaluation), Fiscal Year 1981.

DTIC Science & Technology

1981-01-01

SCIENCE & TECH 162 - UNITED KINGDOM MINISTRY OF DEFENCE 2,670 - UN KINGDOM 162 UN KINGDOM 2,670 INSTITUT FUER ATMOSPHAERISCHE 25 - UNIVERSITE RENE ... DESCARTES 10 - GERMANY 25 FRANCE 10 INVERESK RESEARCH INTERNATIONAL 106 - 8,602 UN KINGDOM 106 ISRAEL INSTITUTE OF TECHNOLOGY 55 - ISRAEL 55 KEELE UNIVERSITY

Toxic Hazards Research Unit. Annual Technical Report. 1978

DTIC Science & Technology

1978-08-01

determinations made for the following battery of clinical tests: HCT Bilirubin RBC Glucose WBC Triglycerides HGB Iron Alkaline Sedimentation Phosphatase Rate ...Count WBC Hematocrit HCT Hemoglobin HGB Sedimentation Rate SEDI Reticulocytes RETIC MCORP Mean Corpuscular Volume MCV Mean Corpuscular Hemoglobin MCH...Contract F33615-76-C-5005 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PPOGPAM ELEMENT, PROJECT , TASK University of California, Irvine APEA A WORK UNIT

48 CFR 25.301-3 - Weapons.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Weapons. 25.301-3 Section... FOREIGN ACQUISITION Contracts Performed Outside the United States 25.301-3 Weapons. The contracting officer shall follow agency procedures and the weapons policy established by the combatant commander or...

48 CFR 25.301-3 - Weapons.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Weapons. 25.301-3 Section... FOREIGN ACQUISITION Contracts Performed Outside the United States 25.301-3 Weapons. The contracting officer shall follow agency procedures and the weapons policy established by the combatant commander or...

48 CFR 25.301-3 - Weapons.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Weapons. 25.301-3 Section... FOREIGN ACQUISITION Contracts Performed Outside the United States 25.301-3 Weapons. The contracting officer shall follow agency procedures and the weapons policy established by the combatant commander or...

48 CFR 25.301-3 - Weapons.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Weapons. 25.301-3 Section... FOREIGN ACQUISITION Contracts Performed Outside the United States 25.301-3 Weapons. The contracting officer shall follow agency procedures and the weapons policy established by the combatant commander or...

48 CFR 25.301-3 - Weapons.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Weapons. 25.301-3 Section... FOREIGN ACQUISITION Contracts Performed Outside the United States 25.301-3 Weapons. The contracting officer shall follow agency procedures and the weapons policy established by the combatant commander or...

Navy DD(X) and LCS Ship Acquisition Programs: Oversight Issues and Options for Congress

DTIC Science & Technology

2005-01-25

PROJECT NUMBER 5e . TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Congressional Research Service,The...the contract for the next phase on a sole-source basis to NGSS . The first DD(X) would be built by Northrop/Ingalls, while the second would be built...by GD/BIW. The Navy has also stated that “The ship construction contracts will be allocated equally between NGSS and BIW for the first six ships

Combat Leadership Styles: Empowerment versus Authoritarianism

DTIC Science & Technology

1990-12-01

Combat Leadership Styles : Empowerment versus Authoritarianism FARIS R. KIRKLAND Recent research in Israel and the United States suggests that...Combat Leadership Styles : Empowerment versus Authoritarianism 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

Evaluation of contract time estimation and contracting procedures : technical summary.

DOT National Transportation Integrated Search

1996-08-01

The objective of this research was 1) to provide the DOTD with a systematic approach to the determination of contract duration, and 2) to explore innovative contracting procedures that may prove beneficial in DOTD projects. The innovative contracting...

Testing of motor unit synchronization model for localized muscle fatigue.

PubMed

Naik, Ganesh R; Kumar, Dinesh K; Yadav, Vivek; Wheeler, Katherine; Arjunan, Sridhar

2009-01-01

Spectral compression of surface electromyogram (sEMG) is associated with onset of localized muscle fatigue. The spectral compression has been explained based on motor unit synchronization theory. According to this theory, motor units are pseudo randomly excited during muscle contraction, and with the onset of muscle fatigue the recruitment pattern changes such that motor unit firings become more synchronized. While this is widely accepted, there is little experimental proof of this phenomenon. This paper has used source dependence measures developed in research related to independent component analysis (ICA) to test this theory.

Muscle vibration sustains motor unit firing rate during submaximal isometric fatigue in humans

PubMed Central

Griffin, L; Garland, S J; Ivanova, T; Gossen, E R

2001-01-01

In keeping with the ‘muscular wisdom hypothesis’, many studies have documented that the firing rate of the majority of motor units decreased during fatiguing isometric contractions. The present study investigated whether the application of periodic muscle vibration, which strongly activates muscle spindles, would alter the modulation of motor unit firing rate during submaximal fatiguing isometric contractions. Thirty-three motor units from the lateral head of the triceps brachii muscle were recorded from 10 subjects during a sustained isometric 20 % maximal voluntary contraction (MVC) of the elbow extensors. Vibration was interposed on the contraction for 2 s every 10 s. Twenty-two motor units were recorded from the beginning of the fatigue task. The discharge rate of the majority of motor units remained constant (12/22) or increased (4/22) with fatigue. Six motor units demonstrated a reduction in discharge rate that later returned toward initial values; these motor units had higher initial discharge rates than the other 16 motor units. In a second series of experiments, four subjects held a sustained isometric 20 % MVC for 2 min and then vibration was applied as above for the remainder of the contraction. In this case, motor units initially demonstrated a decrease in firing rate that increased after the vibration was applied. Thus muscle spindle disfacilitation of the motoneurone pool may be associated with the decline of motor unit discharge rate observed during the first 2 min of the contraction. In a third set of experiments, seven subjects performed the main experiment on one occasion and repeated the fatigue task without vibration on a second occasion. Neither the endurance time of the fatiguing contraction nor the MVC torque following fatigue was affected by the application of vibration. This finding calls into question the applicability of the muscular wisdom hypothesis to submaximal contractions. PMID:11559785

Impact of Scheduled Attrition Rates on Meeting Monthly Sortie Goals in United States Air Force Bomb Wings

DTIC Science & Technology

2009-06-12

predict future losses in the monthly flying schedules. The purpose of the attrition is to ensure that units meet their sortie contract consistently. In...an era of decreasing force size, it is important for units to maximize aircrew training operations, without wasting manpower and resources. Thus, the ...primary research question is as follows: Is the current USAF scheduling technique of using a 5-year historical attrition rate an effective way to

Motor unit recruitment and bursts of activity in the surface electromyogram during a sustained contraction.

PubMed

Riley, Zachary A; Terry, Mary E; Mendez-Villanueva, Alberto; Litsey, Jane C; Enoka, Roger M

2008-06-01

Bursts of activity in the surface electromyogram (EMG) during a sustained contraction have been interpreted as corresponding to the transient recruitment of motor units, but this association has never been confirmed. The current study compared the timing of trains of action potentials discharged by single motor units during a sustained contraction with the bursts of activity detected in the surface EMG signal. The 20 motor units from 6 subjects [recruitment threshold, 35.3 +/- 11.3% maximal voluntary contraction (MVC) force] that were detected with fine wire electrodes discharged 2-9 trains of action potentials (7.2 +/- 5.6 s in duration) when recruited during a contraction that was sustained at a force below its recruitment threshold (target force, 25.4 +/- 10.6% MVC force). High-pass filtering the bipolar surface EMG signal improved its correlation with the single motor unit signal. An algorithm applied to the surface EMG was able to detect 75% of the trains of motor unit action potentials. The results indicate that bursts of activity in the surface EMG during a constant-force contraction correspond to the transient recruitment of higher-threshold motor units in healthy individuals, and these results could assist in the diagnosis and design of treatment in individuals who demonstrate deficits in motor unit activation.

Examination of motor unit control properties of the vastus lateralis in an individual that had acute paralytic poliomyelitis.

PubMed

Herda, Trent J; Cooper, Michael A

2014-08-01

The purpose of the study was to examine motor unit (MU) recruitment and derecruitment thresholds and firing rates of the vastus lateralis between 2 healthy (HE) individuals (women, ages = 19 and 23 years) and 1 individual (man, age = 22 years) who acquired acute poliomyelitis (PO). Each participant performed submaximal isometric trapezoid muscle actions of the leg extensors from 20% to 90% maximal voluntary contraction in 10% increments with a sensor placed on the vastus lateralis to record electromyography. Electromyographic signals were decomposed into the firing events of single MUs. Linear regressions were performed on the firing rates at recruitment and peak firing rates versus the recruitment thresholds and the derecruitment versus recruitment thresholds. In addition, data were pooled together from all contractions to examine differences between PO and HE with independent samples t-tests calculated for firing rates at recruitment, peak firing rates, recruitment thresholds, derecruitment thresholds, and duration of MU activity. The results demonstrated systematic differences in MU control strategies between the PO and HE. There were differences in the recruitment thresholds (P < 0.001; HE = 30.5% ± 22.2% maximal voluntary contraction; PO = 14.5% ± 5.0% maximal voluntary contraction), firing rates at recruitment (P < 0.001; HE = 7.4 ± 2.5 pulses per second; PO = 6.2 ± 1.7 pulses per second) and peak firing rates across the force spectrum (P = 0.001; HE = 22.2 ± 5.8 pulses per second; PO = 20.3 ± 2.3 pulses per second), altered derecruitment versus recruitment relationships (HE slope = 0.82 derec/rec, PO slope = 1.78 derec/rec), and duration of MU activity (P < 0.001) between the PO (18.6 ± 2.4 seconds) and HE (15.3 ± 3.0 seconds). Future research should examine the possible differences in MU behavior between PO and HE as a result of fatigue to further elucidate disease-related changes in MU properties.

9 CFR 206.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... pricing determination included in a contract that establishes a minimum and/or maximum level of base price... premiums or discounts, expressed in dollars per unit. Contract. Any agreement, whether written or verbal... accrues a running positive or negative balance as a result of a pricing determination included in a...

48 CFR 49.206-2 - Bases for settlement proposals.

Code of Federal Regulations, 2013 CFR

2013-10-01

... construction or related professional services contract. (ii) The partial or complete termination of supply... distinguished from a lump-sum) professional services contract. (b) Total cost basis. (1) When use of the..., under the contractor's accounting system, unit costs for work in process and finished products cannot...

48 CFR 49.206-2 - Bases for settlement proposals.

Code of Federal Regulations, 2014 CFR

2014-10-01

... construction or related professional services contract. (ii) The partial or complete termination of supply... distinguished from a lump-sum) professional services contract. (b) Total cost basis. (1) When use of the..., under the contractor's accounting system, unit costs for work in process and finished products cannot...

48 CFR 49.206-2 - Bases for settlement proposals.

Code of Federal Regulations, 2012 CFR

2012-10-01

... construction or related professional services contract. (ii) The partial or complete termination of supply... distinguished from a lump-sum) professional services contract. (b) Total cost basis. (1) When use of the..., under the contractor's accounting system, unit costs for work in process and finished products cannot...

48 CFR 49.206-2 - Bases for settlement proposals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... construction or related professional services contract. (ii) The partial or complete termination of supply... distinguished from a lump-sum) professional services contract. (b) Total cost basis. (1) When use of the..., under the contractor's accounting system, unit costs for work in process and finished products cannot...

48 CFR 4.1001 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Policy. 4.1001 Section 4... MATTERS Administrative Matters 4.1001 Policy. Contracts may identify the items or services to be acquired as separately identified line items. Contract line items should provide unit prices or lump sum...

75 FR 72845 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-26

... contract for future functional equivalence analyses of the GEPS 3 product. \\1\\ Notice of United States... analysis of the formulas, and certification of the Governors' vote; and Attachment 4--an application for... costing information and volume commitments, do not alter the contracts' functional equivalency. Id. at 3-4...

Joint Services Electronics Program.

DTIC Science & Technology

1985-03-31

COJNRACT ON GRANT NuuSER(.j M. Tinkham N00014-84-K-0465 S. PeRFOR MING ORGANIZATION NAME AND ADORESS 𔃺. PROGRAM EL.,IT. P0OJECT. TASA Division of...2 7 R.W. Brockett DlAG29-83-K-0040 TW.osbr AFosR- 81-7401 R.W. Brockett -: DE -FGD2-84-EEw4O1 5B T.T. Wui sER xB-2-02144-l W. Paul JOINT SERVICES...0465, NSF DMR-81-08327 and SERI Subcontract XB-2-02144-1 of DOE Prime Contract DE -AC-02-83-CHI0093; Research Unit 2 (former #3). During this period we

The Effectiveness of United States Coast Guard Participation in the Department of Transportation 8(a) Pilot Program.

DTIC Science & Technology

1987-06-01

Paul J. Seidman, "An Overview of Small and Disadvantaged Business Contracting," National Contract Management Journal 18 (Summer 1985): 5-19. 4. 49...Overview of Small and Disadvantaged Business Contracting," National Contract Management Journal, 18 (Summer 1985): 5-19. 6. National Archives and Records...J. Seidman, "An Overview of Small and Disadvantaged Business Contracting," National Contract Management Journal 18 (Summer 1985): 5-19. 9. 15 United

46 CFR Sec. 3 - Terminal operating contract.

Code of Federal Regulations, 2011 CFR

2011-10-01

... _________, 19__, between the United States of America (herein called the “United States”), acting by and through...'s work under the provisions of this agreement the following: (1) For terminal services, an amount... first above written. (Seal) Attest: united states of america, department of transportation, maritime...

46 CFR Sec. 3 - Terminal operating contract.

Code of Federal Regulations, 2012 CFR

2012-10-01

... _________, 19__, between the United States of America (herein called the “United States”), acting by and through...'s work under the provisions of this agreement the following: (1) For terminal services, an amount... first above written. (Seal) Attest: united states of america, department of transportation, maritime...

Ontic Engineering and Manufacturing Overcharged the Defense Logistics Agency for Sole Source Spare Parts (REDACTED)

DTIC Science & Technology

2014-09-15

Motor3 ~ Total Markup 1 For 20 of the 21 parts, Ontic’s contract unit prices to DLA included royalty fees . Ontic’s contract unit price to DLA for...the Refrigeration Heat Interchanger part did not include royalty fees . 2 Minor inconsistencies in the percent differences may occur due to rounding...historical price analysis for fluid filter covers and alternating current motors was not sufficient to identifyOntic’s overcharges of royalty fees . Ontic’s

48 CFR 252.225-7032 - Waiver of United Kingdom Levies-Evaluation of offers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of a contract, the U.S. Government reserves the right to reduce the contract price by the amount of... Levies—Evaluation of Offers (APR 2003) (a) Offered prices for contracts or subcontracts with United... offeror shall identify to the Contracting Officer all levies included in the offered price by describing...

Hospital contract management: a descriptive profile.

PubMed Central

Alexander, J A; Lewis, B L

1984-01-01

Despite the dramatic growth in hospital contract management in the last decade, research only recently has begun to provide insights into the structure, operation, and effectiveness of these arrangements. Two descriptive questions regarding hospital contract management are addressed in an effort to increase correspondence between theoretical and evaluative research in this area: (1) how do contract-managed hospitals differ from traditionally managed hospitals? and (2) how do contract-managed hospitals differ from each other? Principal discriminating variables in the analyses are hospital size, control, urban-rural location, region, management organization control, and management organization size. Results of the analysis on a sample of 406 contract-managed hospitals and 401 unaffiliated hospitals reveal important differences between contract-managed and traditionally managed hospitals as well as among contract management organizations. These findings are discussed in terms of their implications for future research and performance evaluations on contract management arrangements. PMID:6490376

Challenges With Research Contract Negotiations in Community-Based Cancer Research.

PubMed

Thompson, Michael A; Hurley, Patricia A; Faller, Bryan; Longinette, Jean; Richter, Katie; Stewart, Teresa L; Robert, Nicholas

2016-06-01

Community-based research programs face many barriers to participation in clinical trials. Although the majority of people with cancer are diagnosed and treated in the community setting, only roughly 3% are enrolled onto clinical trials. Research contract and budget negotiations have been consistently identified as time consuming and a barrier to participation in clinical trials. ASCO's Community Research Forum conducted a survey about specific challenges of research contract and budget negotiation processes in community-based research settings. The goal was to ultimately identify potential solutions to these barriers. A survey was distributed to 780 community-based physician investigators and research staff. The survey included questions to provide insight into contract and budget negotiation processes and perceptions about related barriers. A total of 77% of the 150 respondents acknowledged barriers in the process. Respondents most frequently identified budget-related issues (n = 133), inefficiencies in the process (n = 80), or legal review and negotiation issues (n = 70). Of the respondents, 44.1% indicated that contract research organizations made the contract negotiations process harder for their research program, and only 5% believed contract research organizations made the process easier. The contract negotiations process is perceived to be impeded by sponsors through underestimation of costs, lack of flexibility with the contract language, and excessive delays. Improving clinical trial activation processes and reducing inefficiencies would be beneficial to all interested stakeholders, including patients who may ultimately stand to benefit from participation in clinical trials. The following key recommendations were made: standardization of contracts and negotiation processes to promulgate transparency and efficiencies, improve sponsor processes to minimize burden on sites, create and promote use of contract templates and best practices, and provide education and consultation. Copyright © 2016 by American Society of Clinical Oncology.

Motor unit activation patterns during concentric wrist flexion in humans with different muscle fibre composition.

PubMed

Søgaard, K; Christensen, H; Fallentin, N; Mizuno, M; Quistorff, B; Sjøgaard, G

1998-10-01

Muscle activity was recorded from the flexor carpi radialis muscle during static and dynamic-concentric wrist flexion in six subjects, who had exhibited large differences in histochemically identified muscle fibre composition. Motor unit recruitment patterns were identified by sampling 310 motor units and counting firing rates in pulses per second (pps). During concentric wrist flexion at 30% of maximal exercise intensity the mean firing rate was 27 (SD 13) pps. This was around twice the value of 12 (SD 5) pps recorded during sustained static contraction at 30% of maximal voluntary contraction, despite a larger absolute force level during the static contraction. A similar pattern of higher firing rates during dynamic exercise was seen when concentric wrist flexion at 60% of maximal exercise intensity [30 (SD 14) pps] was compared with sustained static contraction at 60% of maximal voluntary contraction [19 (SD 8) pps]. The increase in dynamic exercise intensity was accomplished by recruitment of additional motor units rather than by increasing the firing rate as during static contractions. No difference in mean firing rates was found among subjects with different muscle fibre composition, who had previously exhibited marked differences in metabolic response during corresponding dynamic contractions. It was concluded that during submaximal dynamic contractions motor unit firing rate cannot be deduced from observations during static contractions and that muscle fibre composition may play a minor role.

Force-frequency and fatigue properties of motor units in muscles that control digits of the human hand.

PubMed

Fuglevand, A J; Macefield, V G; Bigland-Ritchie, B

1999-04-01

Modulation of motor unit activation rate is a fundamental process by which the mammalian nervous system encodes muscle force. To identify how rate coding of force may change as a consequence of fatigue, intraneural microstimulation of motor axons was used to elicit twitch and force-frequency responses before and after 2 min of intermittent stimulation (40-Hz train for 330 ms, 1 train/s) in single motor units of human long finger flexor muscles and intrinsic hand muscles. Before fatigue, two groups of units could be distinguished based on the stimulus frequency needed to elicit half-maximal force; group 1 (n = 8) required 9.1 +/- 0.5 Hz (means +/- SD), and group 2 (n = 5) required 15.5 +/- 1.1 Hz. Twitch contraction times were significantly different between these two groups (group 1 = 66. 5 ms; group 2 = 45.9 ms). Overall 18% of the units were fatigue resistant [fatigue index (FI) > 0.75], 64% had intermediate fatigue sensitivity (0.25

48 CFR 48.104-1 - Determining sharing period.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., based on planning and programming or production documentation at the time the VECP is accepted. The.... (c) For engineering-development contracts and contracts containing low-rate-initial-production or early production units, the end of the sharing period is based not on a calendar date, but on acceptance...

48 CFR 48.104-1 - Determining sharing period.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., based on planning and programming or production documentation at the time the VECP is accepted. The.... (c) For engineering-development contracts and contracts containing low-rate-initial-production or early production units, the end of the sharing period is based not on a calendar date, but on acceptance...

48 CFR 48.104-1 - Determining sharing period.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., based on planning and programming or production documentation at the time the VECP is accepted. The.... (c) For engineering-development contracts and contracts containing low-rate-initial-production or early production units, the end of the sharing period is based not on a calendar date, but on acceptance...

48 CFR 48.104-1 - Determining sharing period.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., based on planning and programming or production documentation at the time the VECP is accepted. The.... (c) For engineering-development contracts and contracts containing low-rate-initial-production or early production units, the end of the sharing period is based not on a calendar date, but on acceptance...

32 CFR 32.48 - Contract provisions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 1 2012-07-01 2012-07-01 false Contract provisions. 32.48 Section 32.48 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT... provision to the effect that the recipient, the Department of Defense, the Comptroller General of the United...

32 CFR 32.48 - Contract provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 1 2013-07-01 2013-07-01 false Contract provisions. 32.48 Section 32.48 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT... provision to the effect that the recipient, the Department of Defense, the Comptroller General of the United...

32 CFR 32.48 - Contract provisions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 1 2011-07-01 2011-07-01 false Contract provisions. 32.48 Section 32.48 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT... provision to the effect that the recipient, the Department of Defense, the Comptroller General of the United...

32 CFR 32.48 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Contract provisions. 32.48 Section 32.48 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT... provision to the effect that the recipient, the Department of Defense, the Comptroller General of the United...

48 CFR 53.106 - Special construction and printing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CONTINUED) CLAUSES AND FORMS FORMS General 53.106 Special construction and printing. Contracting offices may... vertical lines omitted (for listing of supplies and services, unit, etc.); (2) As reproducible masters; and... reproducible masters. (c) SF 44— (1) With serial numbers and contracting office name and address; and/or (2) On...

48 CFR 235.017-1 - Sponsoring agreements.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.017-1... Institute of Technology, and Software Engineering Institute operated by Carnegie Mellon) may respond to solicitations and announcements for programs which promote research, development, demonstration, or transfer of...

48 CFR 235.017-1 - Sponsoring agreements.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.017-1... Institute of Technology, and Software Engineering Institute operated by Carnegie Mellon) may respond to solicitations and announcements for programs which promote research, development, demonstration, or transfer of...

Leadership

DTIC Science & Technology

2003-04-07

USAWC STRATEGY RESEARCH PROJECT LEADERSHIP by LIEUTENANT COLONEL RONALD D. JOHNSON United States Army Colonel David R. Brooks Project Advisor The...TITLE AND SUBTITLE Leadership Unclassified 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Johnson, Ronald D. ; Author... Leadership FORMAT: Strategy Research Project DATE: 07 April 2003 PAGES: 28 CLASSIFICATION: Unclassified This SRP shows that values and ethics are essential

Noise Measurements of the VAIIPR Fan

NASA Technical Reports Server (NTRS)

Mendoza, Jeff; Weir, Don

2012-01-01

This final report has been prepared by Honeywell Aerospace, Phoenix, Arizona, a unit of Honeywell International, Inc., documenting work performed during the period September 2004 through November 2005 for the National Aeronautics and Space Administration (NASA) Glenn Research Center, Cleveland, Ohio, under the Revolutionary Aero-Space Engine Research (RASER) Program, Contract No. NAS3- 01136, Task Order 6, Noise Measurements of the VAIIPR Fan. The NASA Task Manager was Dr. Joe Grady, NASA Glenn Research Center, Mail Code 60-6, Cleveland, Ohio 44135. The NASA Contract Officer was Mr. Albert Spence, NASA Glenn Research Center, Mail Code 60-6, Cleveland, Ohio 44135. This report focuses on the evaluation of internal fan noise as generated from various inflow disturbances based on measurements made from a circumferential array of sensors located near the fan and sensors upstream of a serpentine inlet.

40 CFR 52.1488 - Visibility protection.

Code of Federal Regulations, 2011 CFR

2011-07-01

... substituting equivalent or superior control technology, provided such technology meets applicable emission... operator shall meet the following deadlines for design and construction of the emission control equipment... binding contract to design the SO2, opacity and NOX control systems for Unit 1 and Unit 2 by March 1, 2003...

40 CFR 52.1488 - Visibility protection.

Code of Federal Regulations, 2012 CFR

2012-07-01

... substituting equivalent or superior control technology, provided such technology meets applicable emission... operator shall meet the following deadlines for design and construction of the emission control equipment... binding contract to design the SO2, opacity and NOX control systems for Unit 1 and Unit 2 by March 1, 2003...

40 CFR 52.1488 - Visibility protection.

Code of Federal Regulations, 2013 CFR

2013-07-01

... substituting equivalent or superior control technology, provided such technology meets applicable emission... operator shall meet the following deadlines for design and construction of the emission control equipment... binding contract to design the SO2, opacity and NOX control systems for Unit 1 and Unit 2 by March 1, 2003...

40 CFR 52.1488 - Visibility protection.

Code of Federal Regulations, 2010 CFR

2010-07-01

... substituting equivalent or superior control technology, provided such technology meets applicable emission... operator shall meet the following deadlines for design and construction of the emission control equipment... binding contract to design the SO2, opacity and NOX control systems for Unit 1 and Unit 2 by March 1, 2003...

48 CFR 335.070-1 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Policy. 335.070-1 Section... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 335.070-1 Policy. (a) Contracting activities shall encourage... resources available for the conduct of R & D projects and by promoting sound planning and prudent fiscal...

On 10 to 30 m-scale fracture networks in Gale Crater: Contraction of fine-grained sediments due to drying or of frozen sediments due to cooling?

NASA Astrophysics Data System (ADS)

Sletten, Ronald; Hallet, Bernard

2014-05-01

The area in Gale Crater north of the Curiosity landing site has been identified as an alluvial fan [1] and features diverse geological units [2], some with abundant contraction cracks that delineate polygons on the order of 10-30 meters across. These polygons are much larger than the < 1m flagstones seen in Yellowknife by Curiosity [3] and are more suggestive of polygonal patterned ground seen at higher latitudes on Mars [4] and Earth; however, current conditions indicate that ground ice is not stable in Gale Crater [4]. Nevertheless, past conditions, e.g. obliquity changes, may have allowed permafrost to develop and ground ice to form. The domains between the larger polygons are several meters wide, which is consistent with cyclic ratcheting of ice-cemented permafrost (thermal contraction with fractures opening, debris infilling the fractures, and the fractures not closing fully when the ground warms and expands). On the other hand, the large-scale crack networks often seem to be associated with certain lithologic units, including the thinly-bedded, lightly-colored mudstones exposed at Yellowknife. This suggests that the contraction cracks defining these 10 to 30-m polygons, as well as those defining the < 1m flagstones, formed in moist fine-grained sediments that contracted upon desiccation. If the fractures were due to contraction of ice-cemented permafrost, they would be insensitive to the type of sediments they formed in because the mechanical properties would be dominated by ice. The interpretation of the larger-scale crack network is limited to satellite images since Curiosity did not visit this area, and to evidence about surface materials elsewhere in the vicinity of the rover. This evidence points to the former presence of flowing water in Gale Crater and existence of shallow lakes of relatively low salinity and near-neutral pH at Yellowknife [5]. The large amount of contraction in Yellowknife deposits is consistent with a desiccation origin in these deposits as they are fine-grained and contain expandable clay minerals as found by Curiosity [6]. The crack networks may help interpret the past environment in Gale crater. Whether they are formed by ice-cemented permafrost contraction or desiccating lacustrine deposits requires the presence of water; however, the latter case argues for much more extensive presence of liquid water. Acknowledgement: This research is supported by Mars Science Laboratory contract awarded to Malin Space Science Systems References: [1] Williams, R. M. E (2013) Science, 340(6136), 1068-1072., [2] Sumner, D.Y. et al. (2013) LPI Contributions, 1719, 1699, [3] Stewart, W. et al. (2013), GSA Abstracts. v. 45, no. 7, p.4, [4] Mellon, M. T. et al. (1997) J. Geophys. Res., 102(E11), 25617-25628, [5] Grotzinger, J. P (2013) 10.1126/science.1242777, [6] Vaniman, D. T (2013) 10.1126/science.1243480

Can fast-twitch muscle fibres be selectively recruited during lengthening contractions? Review and applications to sport movements.

PubMed

Chalmers, Gordon R

2008-01-01

Literature examining the recruitment order of motor units during lengthening (eccentric) contractions was reviewed to determine if fast-twitch motor units can be active while lower threshold slow-twitch motor units are not active. Studies utilizing surface electromyogram (EMG) amplitude, single motor unit activity, spike amplitude-frequency analyses, EMG power spectrum, mechanomyographic, and phosphocreatine-to-creatine ratio (PCr/Cr) techniques were reviewed. Only single motor unit and PCr/Cr data were found to be suitable to address the goals of this review. Nine of ten single motor unit studies, examining joint movement velocities up to 225 degrees/s and forces up to 53% of a maximum voluntary contraction, found that the size principle of motor unit recruitment applied during lengthening contractions. Deviation from the size principle was demonstrated by one study examining movements within a small range of low velocities and modest forces, although other studies examining similar low forces and lengthening velocities reported size-ordered recruitment. The PCr/Cr data demonstrated the activation of all fibre types in lengthening maximal contractions. Most evidence indicates that for lengthening contractions of a wide range of efforts and speeds, fast-twitch muscle fibres cannot be selectively recruited without activity of the slow-twitch fibres of the same muscle.

Evolved Expendable Launch Vehicle (EELV)

DTIC Science & Technology

2015-12-15

FY13+ Phase I Buy Contractor: United Launch Services, LLC Contractor Location: 9501 East Panorama Circle Centennial , CO 80112 Contract Number...Contract Name: FY13+ Phase I Buy Contractor: United Launch Services, LLC Contractor Location: 9501 East Panorama Circle Centennial , CO 80112 Contract...FY12 EELV Launch Services (ELS5) Contractor: United Launch Services, LLC. Contractor Location: 9501 East Panorama Circle Centennial , CO 80112

48 CFR 235.015-70 - Special use allowances for research facilities acquired by educational institutions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... research facilities acquired by educational institutions. 235.015-70 Section 235.015-70 Federal Acquisition... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.015-70 Special use allowances for research facilities acquired by educational institutions. (a) Definitions. As used in this subsection— (1) Research facility...

48 CFR 32.202-3 - Conducting market research about financing terms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Conducting market research... 32.202-3 Conducting market research about financing terms. Contract financing may be a subject included in the market research conducted in accordance with part 10. If market research for contract...

48 CFR 32.202-3 - Conducting market research about financing terms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Conducting market research... 32.202-3 Conducting market research about financing terms. Contract financing may be a subject included in the market research conducted in accordance with part 10. If market research for contract...

Inlet Geomorphology Evolution

DTIC Science & Technology

2015-04-01

APR 2015 2. REPORT TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Inlet Geomorphology Evolution 5a. CONTRACT NUMBER 5b...Std Z39-18 Coastal Inlets Research Program Inlet Geomorphology Evolution The Inlet Geomorphology Evolution work unit of the CIRP evaluates

Air Force Research Laboratory

DTIC Science & Technology

2009-06-08

Air Force Research Laboratory 8 June 2009 Mr. Leo Marple Ai F R h L b t r orce esearc a ora ory Leo.Marple@wpafb.af.mil DISTRIBUTION STATEMENT A...TITLE AND SUBTITLE Air Force Research Laboratory 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER...5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Air Force Research Laboratory ,Wright

48 CFR 35.009 - Subcontracting research and development effort.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.009 Subcontracting research and development effort. Since the selection of R&D contractors is substantially based on... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Subcontracting research...

Eccentric muscle damage has variable effects on motor unit recruitment thresholds and discharge patterns in elbow flexor muscles.

PubMed

Dartnall, Tamara J; Rogasch, Nigel C; Nordstrom, Michael A; Semmler, John G

2009-07-01

The purpose of this study was to determine the effect of eccentric muscle damage on recruitment threshold force and repetitive discharge properties of low-threshold motor units. Ten subjects performed four tasks involving isometric contraction of elbow flexors while electromyographic (EMG) data were recorded from human biceps brachii and brachialis muscles. Tasks were 1) maximum voluntary contraction (MVC); 2) constant-force contraction at various submaximal targets; 3) motor unit recruitment threshold task; and 4) minimum motor unit discharge rate task. These tasks were performed on three separate days before, immediately after, and 24 h after eccentric exercise of elbow flexor muscles. MVC force declined (42%) immediately after exercise and remained depressed (29%) 24 h later, indicative of muscle damage. Mean motor unit recruitment threshold for biceps brachii was 8.4+/-4.2% MVC, (n=34) before eccentric exercise, and was reduced by 41% (5.0+/-3.0% MVC, n=34) immediately after and by 39% (5.2+/-2.5% MVC, n=34) 24 h after exercise. No significant changes in motor unit recruitment threshold were observed in the brachialis muscle. However, for the minimum tonic discharge rate task, motor units in both muscles discharged 11% faster (10.8+/-2.0 vs. 9.7+/-1.7 Hz) immediately after (n=29) exercise compared with that before (n=32). The minimum discharge rate variability was greater in brachialis muscle immediately after exercise (13.8+/-3.1%) compared with that before (11.9+/-3.1%) and 24 h after exercise (11.7+/-2.4%). No significant changes in minimum discharge rate variability were observed in the biceps brachii motor units after exercise. These results indicate that muscle damage from eccentric exercise alters motor unit recruitment thresholds for >or=24 h, but the effect is not the same in the different elbow flexor muscles.

Assessment of Navy Contract Management Processes

DTIC Science & Technology

2016-02-22

Assessment of Navy Contract Management Processes 22 February 2016 Dr. Rene G. Rendon, Associate Professor Graduate School of Business ...Know) for each survey item in each contract management process area. Acquisition Research Program Graduate School of Business ...management process . Figure 1. U.S. Navy CMMM Maturity Levels Acquisition Research Program Graduate School of Business

Behavior of motor units in human biceps brachii during a submaximal fatiguing contraction.

PubMed

Garland, S J; Enoka, R M; Serrano, L P; Robinson, G A

1994-06-01

The activity of 50 single motor units was recorded in the biceps brachii muscle of human subjects while they performed submaximal isometric elbow flexion contractions that were sustained to induce fatigue. The purposes of this study were to examine the influence of fatigue on motor unit threshold force and to determine the relationship between the threshold force of recruitment and the initial interimpulse interval on the discharge rates of single motor units during a fatiguing contraction. The discharge rate of most motor units that were active from the beginning of the contraction declined during the fatiguing contraction, whereas the discharge rates of most newly recruited units were either constant or increased slightly. The absolute threshold forces of recruitment and derecruitment decreased, and the variability of interimpulse intervals increased after the fatigue task. The change in motor unit discharge rate during the fatigue task was related to the initial rate, but the direction of the change in discharge rate could not be predicted from the threshold force of recruitment or the variability in the interimpulse intervals. The discharge rate of most motor units declined despite an increase in the excitatory drive to the motoneuron pool during the fatigue task.

Filmless Radiology: The Design, Integration, Implementation, and Evaluation of a Digital Imaging Network. Potential Investigations to Be Conducted in Conjunction with the Digital Imaging Network System (DINS) evaluation Project. Revision 1

DTIC Science & Technology

1988-06-01

INSTRUMENT IDENTIFICATION NUMBERORGANIZATION U.S. Army Medical (if aplicable ) Research & Development Command Contract No. DAMDI7-86-C-6145 8c. ADDRESS (City...three echelon levels is delivered from mobile facilities located up to 10, 40, and 150 kilometers from the forward edge of the battle area (FEBA...respectively. There are seven types of Army hospitals used in wartime theaters of operation. They range from Mobile Army Surgical Hospital (MASH) units in

Private Sector Initiative Between the U.S. and Japan

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1998-09-30

OAK-A258 Private Sector Initiative Between the U.S. and Japan. This report for calendar years 1993 through September 1998 describes efforts performed under the Private Sector Initiatives contract. The report also describes those efforts that have continued with private funding after being initiated under this contract. The development of a pyrochemical process, called TRUMP-S, for partitioning actinides from PUREX waste, is described in this report. This effort is funded by the Central Research Institute of Electric Power Industry (CRIEPI), KHI, the United States Department of Energy, and Boeing.

Implementation of Good Clinical Laboratory Practice (GCLP) guidelines within the External Quality Assurance Program Oversight Laboratory (EQAPOL).

PubMed

Todd, Christopher A; Sanchez, Ana M; Garcia, Ambrosia; Denny, Thomas N; Sarzotti-Kelsoe, Marcella

2014-07-01

The EQAPOL contract was awarded to Duke University to develop and manage global proficiency testing programs for flow cytometry-, ELISpot-, and Luminex bead-based assays (cytokine analytes), as well as create a genetically diverse panel of HIV-1 viral cultures to be made available to National Institutes of Health (NIH) researchers. As a part of this contract, EQAPOL was required to operate under Good Clinical Laboratory Practices (GCLP) that are traditionally used for laboratories conducting endpoint assays for human clinical trials. EQAPOL adapted these guidelines to the management of proficiency testing programs while simultaneously incorporating aspects of ISO/IEC 17043 which are specifically designed for external proficiency management. Over the first two years of the contract, the EQAPOL Oversight Laboratories received training, developed standard operating procedures and quality management practices, implemented strict quality control procedures for equipment, reagents, and documentation, and received audits from the EQAPOL Central Quality Assurance Unit. GCLP programs, such as EQAPOL, strengthen a laboratory's ability to perform critical assays and provide quality assessments of future potential vaccines. © 2013.

Overview of NASA Lewis Research Center free-piston Stirling engine activities

NASA Technical Reports Server (NTRS)

Slaby, J. G.

1984-01-01

A generic free-piston Stirling technology project is being conducted to develop technologies generic to both space power and terrestrial heat pump applications in a cooperative, cost-shared effort. The generic technology effort includes extensive parametric testing of a 1 kW free-piston Stirling engine (RE-1000), development of a free-piston Stirling performance computer code, design and fabrication under contract of a hydraulic output modification for RE-1000 engine tests, and a 1000-hour endurance test, under contract, of a 3 kWe free-piston Stirling/alternator engine. A newly initiated space power technology feasibility demonstration effort addresses the capability of scaling a free-piston Stirling/alternator system to about 25 kWe; developing thermodynamic cycle efficiency or equal to 70 percent of Carnot at temperature ratios in the order of 1.5 to 2.0; achieving a power conversion unit specific weight of 6 kg/kWe; operating with noncontacting gas bearings; and dynamically balancing the system. Planned engine and component design and test efforts are described.

48 CFR 2052.235-70 - Publication of research results.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Publication of research....235-70 Publication of research results. As prescribed in 2035.70(a)(1), the contracting officer shall insert the following clause in applicable solicitations and contracts for research and development by...

Kosovo: Unfinished Business

DTIC Science & Technology

2005-03-18

USAWC STRATEGY RESEARCH PROJECT KOSOVO: UNFINISHED BUSINESS by Colonel Heather J. lerardi United States Army Harry Richard Yarger Project Adviser...COVERED 18 MAR 2005 2. REPORT TYPE 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Kosovo Unfinished Business 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...Pirscribed by ANSI Std Z39-18 ii ABSTRACT AUTHOR: Colonel Heather J. lerardi TITLE: Kosovo- Unfinished Business FORMAT: Strategy Research Project DATE: 18

The effects of local forearm muscle cooling on motor unit properties.

PubMed

Mallette, Matthew M; Green, Lara A; Gabriel, David A; Cheung, Stephen S

2018-02-01

Muscle cooling impairs maximal force. Using needle electromyography (EMG) to assess motor unit properties during muscle cooling, is limited and equivocal. Therefore, we aimed to determine the impact of local muscle cooling on motor unit firing properties using surface EMG decomposition. Twenty participants (12 M, 8 F) completed maximal, evoked, and trapezoidal contractions during thermoneutral and cold muscle conditions. Forearm muscle temperature was manipulated using 10-min neutral (~ 32 °C) or 20-min cold (~ 3 °C) water baths. Twitches and maximal voluntary contractions were performed prior to, and after, forearm immersion in neutral or cold water. Motor unit properties were assessed during trapezoidal contractions to 50% baseline force using surface EMG decomposition. Impaired contractile properties from muscle cooling were evident in the twitch amplitude, duration, and rate of force development indicating that the muscle was successfully cooled from the cold water bath (all d ≥ 0.5, P < 0.05). Surface EMG decomposition showed muscle cooling increased the number of motor units (d = 0.7, P = 0.01) and motor unit action potential (MUAP) duration (d = 0.6, P < 0.001), but decreased MUAP amplitude (d = 0.2, P = 0.012). Individually, neither motor unit firing rates (d = 0.1, P = 0.843) nor recruitment threshold (d = 0.1, P = 0.746) changed; however, the relationship between the recruitment threshold and motor unit firing rate was steeper (d = 1.0, P < 0.001) and had an increased y-intercept (d = 0.9, P = 0.007) with muscle cooling. Since muscle contractility is impaired with muscle cooling, these findings suggest a compensatory increase in the number of active motor units, and small but coupled changes in motor unit firing rates and recruitment threshold to produce the same force.

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2012 CFR

2012-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2014 CFR

2014-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2011 CFR

2011-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2013 CFR

2013-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

Motor Unit Interpulse Intervals During High Force Contractions.

PubMed

Stock, Matt S; Thompson, Brennan J

2016-01-01

We examined the means, medians, and variability for motor-unit interpulse intervals (IPIs) during voluntary, high force contractions. Eight men (mean age = 22 years) attempted to perform isometric contractions at 90% of their maximal voluntary contraction force while bipolar surface electromyographic (EMG) signals were detected from the vastus lateralis and vastus medialis muscles. Surface EMG signal decomposition was used to determine the recruitment thresholds and IPIs of motor units that demonstrated accuracy levels ≥ 96.0%. Motor units with high recruitment thresholds demonstrated longer mean IPIs, but the coefficients of variation were similar across all recruitment thresholds. Polynomial regression analyses indicated that for both muscles, the relationship between the means and standard deviations of the IPIs was linear. The majority of IPI histograms were positively skewed. Although low-threshold motor units were associated with shorter IPIs, the variability among motor units with differing recruitment thresholds was comparable.

48 CFR 229.402-70 - Additional provisions and clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... clause at 252.229-7006, Value Added Tax Exclusion (United Kingdom), in solicitations and contracts when... from Customs Duty and Value Added Tax on Fuel (Passenger Vehicles) (United Kingdom), in solicitations... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS TAXES Contract Clauses 229.402-70...

48 CFR 229.402-70 - Additional clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Value Added Tax on Fuel (Passenger Vehicles) (United Kingdom), in solicitations issued and contracts... contain the clause at 252.229-7005, Tax Exemptions (Spain). (f) Use the clause at 252.229-7006, Value Added Tax Exclusion (United Kingdom), in solicitations and contracts when contract performance will be...

Motor unit activity after eccentric exercise and muscle damage in humans.

PubMed

Semmler, J G

2014-04-01

It is well known that unaccustomed eccentric exercise leads to muscle damage and soreness, which can produce long-lasting effects on muscle function. How this muscle damage influences muscle activation is poorly understood. The purpose of this brief review is to highlight the effect of eccentric exercise on the activation of muscle by the nervous system, by examining the change in motor unit activity obtained from surface electromyography (EMG) and intramuscular recordings. Previous research shows that eccentric exercise produces unusual changes in the EMG–force relation that influences motor performance during isometric, shortening and lengthening muscle contractions and during fatiguing tasks. When examining the effect of eccentric exercise at the single motor unit level, there are substantial changes in recruitment thresholds, discharge rates, motor unit conduction velocities and synchronization, which can last for up to 1 week after eccentric exercise. Examining the time course of these changes suggests that the increased submaximal EMG after eccentric exercise most likely occurs through a decrease in motor unit conduction velocity and an increase in motor unit activity related to antagonist muscle coactivation and low-frequency fatigue. Furthermore, there is a commonly held view that eccentric exercise produces preferential damage to high-threshold motor units, but the evidence for this in humans is limited. Further research is needed to establish whether there is preferential damage to high-threshold motor units after eccentric exercise in humans, preferably by linking changes in motor unit activity with estimates of motor unit size using selective intramuscular recording techniques.

Small Business Innovations (Mass Microbalance)

NASA Technical Reports Server (NTRS)

1991-01-01

Femtometrics of Costa Mesa, CA, developed the Model 200-1 SAW Mass Microbalance under a NASA Small Business Innovation Research (SBIR) contract with Langley Research Center. The product is described as "the next generation of aerosol mass microbalance technology," because a new type of sensor, the Surface Acoustic Wave (SAW) piezoelectric crystal, offers mass resolution two orders of magnitude greater than the Quartz Crystal Microbalance cascade impactor (QCM) (used at Langley since 1979 for collection and measurement of aerosol particles in the upper atmosphere). The Model 200-1 SAW Mass Microbalance, which provides a 400-fold increase in mass sensitivity per unit area over the QCM, can be used for real-time particle monitoring in clean rooms, measuring chemical vapors in very low concentrations, measuring target chemicals in the stratosphere and in industry as a toxic vapor monitor.

Prostate Cancer Research Training Program

DTIC Science & Technology

2017-09-01

Award Number: W81XWH-16-1-0549 TITLE: Prostate Cancer Research Training Program PRINCIPAL INVESTIGATOR: David M. Lubaroff, PhD CONTRACTING...ORGANIZATION: University of Iowa Iowa City, IA 52242 REPORT DATE: September 2017 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research ...Prostate Cancer Research Training Program 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-1-0549 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S

Young People's Views on Distributive Justice, Rights, and Obligations: A Cross-Cultural Study.

ERIC Educational Resources Information Center

Jonsson, Britta; Flanagan, Constance

2000-01-01

Presents the results from a cross-cultural research project that explored adolescents' interpretation of the social contract (obligations, rights, and responsibilities between individuals and society) in seven countries, including Australia, Bulgaria, Czech Republic, Hungary, Russia, Sweden, and the United States. Includes appendices and…

Extensions to Polychain: Nonseparability Testing and Factoring Algorithm.

DTIC Science & Technology

1985-12-02

Cientifico e Tecnologico - CNPq, Brazil. Reproduction in wholeI or in part is permitted for any purpose of the United States Government. A...supported by Conselho Nacional de Desenvolvimento Cientifico e Tecnol6gico - CNPq, Brazil, and the Office of Naval Research, under contract N00014-85-K

29 CFR 4.187 - Recovery of underpayments.

Code of Federal Regulations, 2010 CFR

2010-07-01

...), cert. denied, 350 U.S. 902), and to give contracting agency reprocurement claims priority would be to.... United States, 132 Ct. Cl. 529 (1955), in which the courts gave priority to sureties who had paid unpaid..., PC-330, October 3, 1947; Reynolds Research Corp., Decision of the Administrator, PC-381, October 24...

48 CFR 47.207-11 - Volume movements within the contiguous United States.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Volume movements within... Transportation-Related Services 47.207-11 Volume movements within the contiguous United States. (a) For purposes of contract administration, a volume movement is— (1) In DoD, the aggregate of freight shipments...

7 CFR 28.161 - Disputes involving contracts for shipment of cotton from United States.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Disputes involving contracts for shipment of cotton... COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Regulations Under the United States Cotton Standards Act Adjustment of Contract Disputes § 28.161 Disputes involving...

7 CFR 28.161 - Disputes involving contracts for shipment of cotton from United States.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 2 2011-01-01 2011-01-01 false Disputes involving contracts for shipment of cotton... COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Regulations Under the United States Cotton Standards Act Adjustment of Contract Disputes § 28.161 Disputes involving...

7 CFR 28.161 - Disputes involving contracts for shipment of cotton from United States.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 2 2012-01-01 2012-01-01 false Disputes involving contracts for shipment of cotton... COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Regulations Under the United States Cotton Standards Act Adjustment of Contract Disputes § 28.161 Disputes involving...

7 CFR 28.161 - Disputes involving contracts for shipment of cotton from United States.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Disputes involving contracts for shipment of cotton... COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Regulations Under the United States Cotton Standards Act Adjustment of Contract Disputes § 28.161 Disputes involving...

7 CFR 28.161 - Disputes involving contracts for shipment of cotton from United States.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Disputes involving contracts for shipment of cotton... COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Regulations Under the United States Cotton Standards Act Adjustment of Contract Disputes § 28.161 Disputes involving...

48 CFR 229.402-70 - Additional provisions and clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Value Added Tax on Fuel (Passenger Vehicles) (United Kingdom), in solicitations issued and contracts... contain the clause at 252.229-7005, Tax Exemptions (Spain). (f) Use the clause at 252.229-7006, Value Added Tax Exclusion (United Kingdom), in solicitations and contracts when contract performance will be...

Examination of Chesapeake Bay Observing System for Local Environmental Data for Coast Guard Operations

DTIC Science & Technology

2004-12-01

U.S. Coast Guard Research and Development Center 1082 Shennecossett Road, Groton, CT 06340-6048 Report No. CG-D-04-05 Examination of Chesapeake Bay...Director "United States Coast Guard Research & Development Center 1082 Shennecossett Road r Groton, CT 06340-6048 ii Technical Report Documentation Page...and Mary Research & Development Center 11. Contract or Grant No. Route 1208, Greate Road 1082 Shennecossett Road DTCG32-03-C-R0006 Gloucester Point, VA

Preparing Brigade Combat Team Soldiers for Mission Readiness Through Research on Intangible Psychological Constructs and their Applications: Validation and Pilot

DTIC Science & Technology

2015-01-01

and their Applications: Validation and Pilot Steven N. Aude Kenneth Nicely Michael A. Lodato ICF International Christopher L. Vowels...CONTRACT OR GRANT NUMBER W5J9CQ-11-0009 5b. PROGRAM ELEMENT NUMBER 622785 6. AUTHOR(S) Steven N. Aude, Kenneth Nicely, Michael A... Michael A. Lodato ICF International Christopher L. Vowels U.S. Army Research Institute Fort Hood Research Unit Brian T. Crabb

SEGMAG Machines for Marine Electrical Propulsion Systems

DTIC Science & Technology

1978-09-13

78-9B2-SYSTA-Rj P4 SIG•(AG MACHINES VOR MARINE ELECTRICAL PROPULSION SYSTBILS Final Report Submitted to Office of Naval Research R.A. Feranchak, R. B...MACHINES FOR MARINE ELECTRICAL PROPULSION SYSTEMS Final Technical Report Submitted to Office of Naval Research Contract N00014-.77-C-0307 Feranchak, R. A...OF0ANI ZATION NAME AND ADDRESS 0., PROGRAM ELtEMNT.PROJECT, TASK~~.i~ckev ~eiAREA & WORK UNIT NUMBERS Westinghouse Research & Develepment Center 1310

Advanced Stirling Convertor (ASC) - From Technology Development to Future Flight Product

NASA Technical Reports Server (NTRS)

Wong, Wayne A.; Wood, J. Gary; Wilson, Kyle

2008-01-01

The Advanced Stirling Convertor (ASC) is being developed by Sunpower, Inc. under contract to NASA s Glenn Research Center (GRC) with critical technology support tasks lead by GRC. The ASC development, funded by NASA s Science Mission Directorate, started in 2003 as one of 10 competitively awarded contracts that were to address future Radioisotope Power System (RPS) advanced power conversion needs. The ASC technology has since evolved through progressive convertor builds and successful testing to demonstrate high conversion efficiency (38 %), low mass (1.3 kg), hermetic sealing, launch vibration simulation, EMI characterization, and is undergoing extended operation. The GRC and Sunpower team recently delivered three ASC-E machines to the Department of Energy (DOE) and Lockheed Martin Space Systems Company, two units for integration onto the Advanced Stirling Radioisotope Generator Engineering Unit (ASRG EU) plus one spare. The design has recently been initiated for the ASC-E2, an evolution from the ASC-E that substitutes higher temperature materials enabling improved performance and higher reliability margins. This paper summarizes the history and status of the ASC project and discusses plans for this technology which enables RPS specific power of 8 W/kg for future NASA missions.

7 CFR 763.3 - Full faith and credit.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 7 2012-01-01 2012-01-01 false Full faith and credit. 763.3 Section 763.3 Agriculture... SPECIAL PROGRAMS LAND CONTRACT GUARANTEE PROGRAM (Eff. 1-3-12) § 763.3 Full faith and credit. (a) The land contract guarantee constitutes an obligation supported by the full faith and credit of the United States...

75 FR 18113 - Magnuson-Stevens Act Provisions; Fisheries of the Northeastern United States; Northeast...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-09

... final operations plan, contract, and environmental assessment (EA), and the Final Regulatory Flexibility... fish in a given FY, it must submit an operations plan, sector contract, and EA to NMFS by September 1... National Environmental Policy Act (NEPA), an EA was prepared for each operations plan. All sector EAs are...

7 CFR 632.31 - Cost-share payment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... out the contract, the land user is indebted to the United States for the cost of the misused material... contract. The cost-share payment is to be determined by one of the following methods: (1) Average cost. (2) Actual cost but not more than the average cost. (3) Specified maximum cost. If the average cost or the...

7 CFR 632.31 - Cost-share payment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... out the contract, the land user is indebted to the United States for the cost of the misused material... contract. The cost-share payment is to be determined by one of the following methods: (1) Average cost. (2) Actual cost but not more than the average cost. (3) Specified maximum cost. If the average cost or the...

7 CFR 632.31 - Cost-share payment.

Code of Federal Regulations, 2014 CFR

2014-01-01

... out the contract, the land user is indebted to the United States for the cost of the misused material... contract. The cost-share payment is to be determined by one of the following methods: (1) Average cost. (2) Actual cost but not more than the average cost. (3) Specified maximum cost. If the average cost or the...

7 CFR 632.31 - Cost-share payment.

Code of Federal Regulations, 2013 CFR

2013-01-01

... out the contract, the land user is indebted to the United States for the cost of the misused material... contract. The cost-share payment is to be determined by one of the following methods: (1) Average cost. (2) Actual cost but not more than the average cost. (3) Specified maximum cost. If the average cost or the...

7 CFR 632.31 - Cost-share payment.

Code of Federal Regulations, 2012 CFR

2012-01-01

... out the contract, the land user is indebted to the United States for the cost of the misused material... contract. The cost-share payment is to be determined by one of the following methods: (1) Average cost. (2) Actual cost but not more than the average cost. (3) Specified maximum cost. If the average cost or the...

46 CFR 190.15-90 - Vessels contracted for prior to March 1, 1968.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Vessels contracted for prior to March 1, 1968. 190.15-90 Section 190.15-90 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS CONSTRUCTION AND ARRANGEMENT Ventilation § 190.15-90 Vessels contracted for prior to March 1, 1968...

46 CFR 190.10-90 - Vessels contracted for prior to March 1, 1968.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Vessels contracted for prior to March 1, 1968. 190.10-90 Section 190.10-90 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS CONSTRUCTION AND ARRANGEMENT Means of Escape § 190.10-90 Vessels contracted for prior to March 1...

Discharge characteristics of biceps brachii motor units at recruitment when older adults sustained an isometric contraction.

PubMed

Pascoe, Michael A; Holmes, Matthew R; Enoka, Roger M

2011-02-01

The purpose of this study was to compare the discharge characteristics of motor units recruited during an isometric contraction that was sustained with the elbow flexor muscles by older adults at target forces that were less than the recruitment threshold force of each isolated motor unit. The discharge times of 27 single motor units were recorded from the biceps brachii in 11 old adults (78.8 ± 5.9 yr). The target force was set at either a relatively small (6.6 ± 3.7% maximum) or large (11.4 ± 4.5% maximum) difference below the recruitment threshold force and the contraction was sustained until the motor unit was recruited and discharged action potentials for about 60 s. The time to recruitment was longer for the large target-force difference (P = 0.001). At recruitment, the motor units discharged repetitively for both target-force differences, which contrasts with data from young adults when motor units discharged intermittently at recruitment for the large difference between recruitment threshold force and target force. The coefficient of variation (CV) for the first five interspike intervals (ISIs) increased from the small (18.7 ± 7.9) to large difference (35.0 ± 10.2%, P = 0.008) for the young adults, but did not differ for the two target force differences for the old adults (26.3 ± 14.7 to 24.0 ± 13.1%, P = 0.610). When analyzed across the discharge duration, the average CV for the ISI decreased similarly for the two target-force differences (P = 0.618) in old adults. These findings contrast with those of young adults and indicate that the integration of synaptic input during sustained contractions differs between young and old adults.

48 CFR 35.016 - Broad agency announcement.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Scientific Review (see 6.102(d)(2)) for the acquisition of basic and applied research and that part of... CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.016 Broad agency announcement. (a) General... documents, shall— (1) Describe the agency's research interest, either for an individual program requirement...

Influencing Helmand: United States Marine Corps Operations in Helmand Province, Afghanistan, in 2008

DTIC Science & Technology

2010-04-14

8217 Master of Military Studies Research Paper September 2009- April 2010 4. TITLE AND SUBTITLE Sa. CONTRACT NUMBER Influencing Helmand: United States...Staff College Marine Corps University 2076 South Street Marine Corps Combat Development Command Quantico, Virginia 22134-5068 MASTER OF MILITARY...THE REQUIREMENTS FOR THE DEGREE OF MASTER OF MILITARY STUDIES MAJOR SEAN DYNAN AY 09-10 Mentor and Or Approved:ti~~~~::.L~~~~~...,u

Lights, Camera, Action: Getting Back to the Basics

DTIC Science & Technology

2009-02-01

Donald Baucom, author of “The Professional Soldier and the Warrior Spirit,” asserts that the military leans towards technology, and leaders who...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR (S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...of the author and do not necessarily represent the views of the Air Force Research Institute, the United States Air Force, the Department of Defense

Life science payload definition and integration study, task C and D. Volume 3: Appendices

NASA Technical Reports Server (NTRS)

1973-01-01

Research equipment requirements were based on the Mini-7 and Mini-30 laboratory concepts defined in Tasks A and B of the intial LSPD contract. Modified versions of these laboratories and the research equipment within them were to be used in three missions of Shuttle/Sortie Module. These were designated (1) the shared 7-day laboratory (a mission with the life sciences laboratory sharing the sortie module with another scientific laboratory), (2) the dedicated 7-day laboratory (full use of the sortie module), and (3) the dedicated 30-day laboratory (full sortie module use with a 30-day mission duration). In defining the research equipment requirements of these laboratories, the equipment was grouped according to its function, and equipment unit data packages were prepared.

Complex myograph allows the examination of complex muscle contractions for the assessment of muscle force, shortening, velocity, and work in vivo

PubMed Central

Rahe-Meyer, Niels; Pawlak, Matthias; Weilbach, Christian; Osthaus, Wilhelm Alexander; Ruhschulte, Hainer; Solomon, Cristina; Piepenbrock, Siegfried; Winterhalter, Michael

2008-01-01

Background The devices used for in vivo examination of muscle contractions assess only pure force contractions and the so-called isokinetic contractions. In isokinetic experiments, the extremity and its muscle are artificially moved with constant velocity by the measuring device, while a tetanic contraction is induced in the muscle, either by electrical stimulation or by maximal voluntary activation. With these systems, experiments cannot be performed at pre-defined, constant muscle length, single contractions cannot be evaluated individually and the separate examination of the isometric and the isotonic components of single contractions is not possible. Methods The myograph presented in our study has two newly developed technical units, i.e. a). a counterforce unit which can load the muscle with an adjustable, but constant force and b). a length-adjusting unit which allows for both the stretching and the contraction length to be infinitely adjustable independently of one another. The two units support the examination of complex types of contraction and store the counterforce and length-adjusting settings, so that these conditions may be accurately reapplied in later sessions. Results The measurement examples presented show that the muscle can be brought to every possible pre-stretching length and that single isotonic or complex isometric-isotonic contractions may be performed at every length. The applied forces act during different phases of contraction, resulting into different pre- and after-loads that can be kept constant – uninfluenced by the contraction. Maximal values for force, shortening, velocity and work may be obtained for individual muscles. This offers the possibility to obtain information on the muscle status and to monitor its changes under non-invasive measurement conditions. Conclusion With the Complex Myograph, the whole spectrum of a muscle's mechanical characteristics may be assessed. PMID:18616815

Change in muscle fascicle length influences the recruitment and discharge rate of motor units during isometric contractions.

PubMed

Pasquet, Benjamin; Carpentier, Alain; Duchateau, Jacques

2005-11-01

This study examines the effect of fascicle length change on motor-unit recruitment and discharge rate in the human tibialis anterior (TA) during isometric contractions of various intensities. The torque produced during dorsiflexion and the surface and intramuscular electromyograms (EMGs) from the TA were recorded in eight subjects. The behavior of the same motor unit (n = 59) was compared at two ankle joint angles (+10 and -10 degrees around the ankle neutral position). Muscle fascicle length of the TA was measured noninvasively using ultrasonography recordings. When the ankle angle was moved from 10 degrees plantarflexion to 10 degrees dorsiflexion, the torque produced during maximal voluntary contraction (MVC) was significantly reduced [35.2 +/- 3.3 vs. 44.3 +/- 4.2 (SD) Nm; P < 0.001] and the average surface EMG increased (0.47 +/- 0.08 vs. 0.43 +/- 0.06 mV; P < 0.05). At reduced ankle joint angle, muscle fascicle length declined by 12.7% (P < 0.01) at rest and by 18.9% (P < 0.001) during MVC. Motor units were activated at a lower recruitment threshold for short compared with long muscle fascicle length, either when expressed in absolute values (2.1 +/- 2.5 vs. 3.6 +/- 3.7 Nm; P < 0.001) or relative to their respective MVC (5.2 +/- 6.1 vs. 8.8 +/- 9.0%). Higher discharge rate and additional motor-unit recruitment were observed at a given absolute or relative torque when muscle fascicles were shortened. However, the data indicate that increased rate coding was mainly present at low torque level (<10% MVC), when the muscle-tendon complex was compliant, whereas recruitment of additional motor units played a dominant role at higher torque level and decreased compliance (10-35% MVC). Taken together, the results suggest that the central command is modulated by the afferent proprioceptive information during submaximal contractions performed at different muscle fascicle lengths.

Time Perception and Evoked Potentials

DTIC Science & Technology

1988-07-01

ARI Research Note 88-69 0 MitnS.Ktohe U.0 ... Ann-r (. Time Perception and Evoked Potentials Paul FraisseDT ( Lfniversit6 Rene Descartes E LECTE...JOHNSON 00L, [N Technical Dicctojr Cmad Research accomplished under contract for the Department of the Army C. Universite Rene Descartes , Paris )r...ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK Labrato-ire de Psychologie Experimental AREA• WORK UNIT NUMBERS Universite Rene Descartes

Time-related changes in firing rates are influenced by recruitment threshold and twitch force potentiation in the first dorsal interosseous.

PubMed

Miller, Jonathan D; Herda, Trent J; Trevino, Michael A; Sterczala, Adam J; Ciccone, Anthony B

2017-08-01

What is the central question of this study? The influences of motor unit recruitment threshold and twitch force potentiation on the changes in firing rates during steady-force muscular contractions are not well understood. What is the main finding and its importance? The behaviour of motor units during steady force was influenced by recruitment threshold, such that firing rates decreased for lower-threshold motor units but increased for higher-threshold motor units. In addition, individuals with greater changes in firing rates possessed greater twitch force potentiation. There are contradictory reports regarding changes in motor unit firing rates during steady-force contractions. Inconsistencies are likely to be the result of previous studies disregarding motor unit recruitment thresholds and not examining firing rates on a subject-by-subject basis. It is hypothesized that firing rates are manipulated by twitch force potentiation during contractions. Therefore, in this study we examined time-related changes in firing rates at steady force in relationship to motor unit recruitment threshold in the first dorsal interosseous and the influence of twitch force potentiation on such changes in young versus aged individuals. Subjects performed a 12 s steady-force contraction at 50% maximal voluntary contraction, with evoked twitches before and after the contraction to quantify potentiation. Firing rates, in relationship to recruitment thresholds, were determined at the beginning, middle and end of the steady force. There were no firing rate changes for aged individuals. For the young, firing rates decreased slightly for lower-threshold motor units but increased for higher-threshold motor units. Twitch force potentiation was greater for young than aged subjects, and changes in firing rates were correlated with twitch force potentiation. Thus, individuals with greater increases in firing rates of higher-threshold motor units and decreases in lower-threshold motor units possessed greater twitch force potentiation. Overall, changes in firing rates during brief steady-force contractions are dependent on recruitment threshold and explained in part by twitch force potentiation. Given that firing rate changes were measured in relationship to recruitment threshold, this study illustrates a more complete view of firing rate changes during steady-force contractions. © 2017 The Authors. Experimental Physiology © 2017 The Physiological Society.

Defense Small Business Innovation Research Program (SBIR). Volume 4. Defense Agencies Abstracts of Phase 1 Awards. 1990

DTIC Science & Technology

1990-01-01

RI 02871 Program Manager: T. DEEGAN Contract #: Title: LF DETECTION OF AIRCRAFT Topic #: DARPA90-049 Office: ID #: 50506 TECHNICAL ABSTRACT - COMBAT...INNOVATION RESEARCH PROGRAM - PHASE I SDIO Solicitation 90.1 TORRANCE, CA 90505 Program Manager: JAMES E CRAIG Contract #: Title: NONINTRUSIVE OPTICAL

Adjustments differ among low-threshold motor units during intermittent, isometric contractions.

PubMed

Farina, Dario; Holobar, Ales; Gazzoni, Marco; Zazula, Damjan; Merletti, Roberto; Enoka, Roger M

2009-01-01

We investigated the changes in muscle fiber conduction velocity, recruitment and derecruitment thresholds, and discharge rate of low-threshold motor units during a series of ramp contractions. The aim was to compare the adjustments in motor unit activity relative to the duration that each motor unit was active during the task. Multichannel surface electromyographic (EMG) signals were recorded from the abductor pollicis brevis muscle of eight healthy men during 12-s contractions (n = 25) in which the force increased and decreased linearly from 0 to 10% of the maximum. The maximal force exhibited a modest decline (8.5 +/- 9.3%; P < 0.05) at the end of the task. The discharge times of 73 motor units that were active for 16-98% of the time during the first five contractions were identified throughout the task by decomposition of the EMG signals. Action potential conduction velocity decreased during the task by a greater amount for motor units that were initially active for >70% of the time compared with that of less active motor units. Moreover, recruitment and derecruitment thresholds increased for these most active motor units, whereas the thresholds decreased for the less active motor units. Another 18 motor units were recruited at an average of 171 +/- 32 s after the beginning of the task. The recruitment and derecruitment thresholds of these units decreased during the task, but muscle fiber conduction velocity did not change. These results indicate that low-threshold motor units exhibit individual adjustments in muscle fiber conduction velocity and motor neuron activation that depended on the relative duration of activity during intermittent contractions.

Characteristics of Biostatistics, Epidemiology, and Research Design Programs in Institutions with Clinical and Translational Science Awards

PubMed Central

Rahbar, Mohammad H.; Dickerson, Aisha S.; Ahn, Chul; Carter, Rickey E.; Hessabi, Manouchehr; Lindsell, Christopher J.; Nietert, Paul J.; Oster, Robert A.; Pollock, Brad H.; Welty, Leah J.

2016-01-01

Purpose To learn the size, composition, and scholarly output of Biostatistics, Epidemiology, and Research Design (BERD) units in U.S. academic health centers (AHCs). Method Each year for four years, the authors surveyed all BERD units in U.S. AHCs that were members of the Clinical and Translational Science Award (CTSA) Consortium. In 2010, 46 BERD units were surveyed; in 2011, 55; in 2012, 60; and in 2013, 61. Results Response rates to the 2010, 2011, 2012, and 2013 surveys were 93.5%, 98.2%, 98.3%, and 86.9%, respectively. Overall, the size of BERD units ranged from 3-86 individuals. The median FTE in BERD units remained similar and ranged from 3.0 to 3.5 FTEs over the years. BERD units reported more availability of doctoral-level biostatisticians than doctoral-level epidemiologists. In 2011, 2012, and 2013, more than a third of BERD units provided consulting support on 101 to 200 projects. A majority of BERD units reported that between 25% and 75% (in 2011) and 31%-70% (in 2012) of their consulting was to junior investigators. More than two thirds of BERD units reported their contributions to the submission of 20 or more non-BERD grant or contract applications annually. Nearly half of BERD units reported 1 to 10 manuscripts submitted annually with a BERD practitioner as the first or corresponding author. Conclusions The survey findings regarding BERD units provide a benchmark against which to compare BERD resources and may be particularly useful for institutions planning to develop new units to support programs such as the CTSA. PMID:27580435

Characteristics of Biostatistics, Epidemiology, and Research Design Programs in Institutions With Clinical and Translational Science Awards.

PubMed

Rahbar, Mohammad H; Dickerson, Aisha S; Ahn, Chul; Carter, Rickey E; Hessabi, Manouchehr; Lindsell, Christopher J; Nietert, Paul J; Oster, Robert A; Pollock, Brad H; Welty, Leah J

2017-02-01

To learn the size, composition, and scholarly output of biostatistics, epidemiology, and research design (BERD) units in U.S. academic health centers (AHCs). Each year for four years, the authors surveyed all BERD units in U.S. AHCs that were members of the Clinical and Translational Science Award (CTSA) Consortium. In 2010, 46 BERD units were surveyed; in 2011, 55; in 2012, 60; and in 2013, 61. Response rates to the 2010, 2011, 2012, and 2013 surveys were 93.5%, 98.2%, 98.3%, and 86.9%, respectively. Overall, the size of BERD units ranged from 3 to 86 individuals. The median FTE in BERD units remained similar and ranged from 3.0 to 3.5 FTEs over the years. BERD units reported more availability of doctoral-level biostatisticians than doctoral-level epidemiologists. In 2011, 2012, and 2013, more than a third of BERD units provided consulting support on 101 to 200 projects. A majority of BERD units reported that between 25% and 75% (in 2011) and 31% to 70% (in 2012) of their consulting was to junior investigators. More than two-thirds of BERD units reported their contributions to the submission of 20 or more non-BERD grant or contract applications annually. Nearly half of BERD units reported 1 to 10 manuscripts submitted annually with a BERD practitioner as the first or corresponding author. The findings regarding BERD units provide a benchmark against which to compare BERD resources and may be particularly useful for institutions planning to develop new units to support programs such as the CTSA.

Activation properties of trigeminal motoneurons in participants with and without bruxism

PubMed Central

D'Amico, Jessica M.; Yavuz, Ş. Utku; Saraçoğlu, Ahmet; Atiş, Elif Sibel; Türker, Kemal S.

2013-01-01

In animals, sodium- and calcium-mediated persistent inward currents (PICs), which produce long-lasting periods of depolarization under conditions of low synaptic drive, can be activated in trigeminal motoneurons following the application of the monoamine serotonin. Here we examined if PICs are activated in human trigeminal motoneurons during voluntary contractions and under physiological levels of monoaminergic drive (e.g., serotonin and norepinephrine) using a paired motor unit analysis technique. We also examined if PICs activated during voluntary contractions are larger in participants who demonstrate involuntary chewing during sleep (bruxism), which is accompanied by periods of high monoaminergic drive. In control participants, during a slowly increasing and then decreasing isometric contraction, the firing rate of an earlier-recruited masseter motor unit, which served as a measure of synaptic input to a later-recruited test unit, was consistently lower during derecruitment of the test unit compared with at recruitment (ΔF = 4.6 ± 1.5 imp/s). The ΔF, therefore, is a measure of the reduction in synaptic input needed to counteract the depolarization from the PIC to provide an indirect estimate of PIC amplitude. The range of ΔF values measured in the bruxer participants during similar voluntary contractions was the same as in controls, suggesting that abnormally high levels of monoaminergic drive are not continually present in the absence of involuntary motor activity. We also observed a consistent “onion skin effect” during the moderately sized contractions (<20% of maximal), whereby the firing rate of higher threshold motor units discharged at slower rates (by 4–7 imp/s) compared with motor units with relatively lower thresholds. The presence of lower firing rates in the more fatigue-prone, higher threshold trigeminal motoneurons, in addition to the activation of PICs, likely facilitates the activation of the masseter muscle during motor activities such as eating, nonnutritive chewing, clenching, and yawning. PMID:24068753

24 CFR 881.502 - Term of contract.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Payments Contract § 881.502 Term of contract. (a) Term (except for Manufactured Home Parks). The term of... acquisition of the property; and (ii) For assisted units in a project financed with the aid of a loan insured... assistance. (b) Term for manufactured home parks. For manufactured home units or spaces in substantially...

24 CFR 881.502 - Term of contract.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Payments Contract § 881.502 Term of contract. (a) Term (except for Manufactured Home Parks). The term of... acquisition of the property; and (ii) For assisted units in a project financed with the aid of a loan insured... assistance. (b) Term for manufactured home parks. For manufactured home units or spaces in substantially...

24 CFR 881.502 - Term of contract.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Payments Contract § 881.502 Term of contract. (a) Term (except for Manufactured Home Parks). The term of... acquisition of the property; and (ii) For assisted units in a project financed with the aid of a loan insured... assistance. (b) Term for manufactured home parks. For manufactured home units or spaces in substantially...

24 CFR 881.502 - Term of contract.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Payments Contract § 881.502 Term of contract. (a) Term (except for Manufactured Home Parks). The term of... acquisition of the property; and (ii) For assisted units in a project financed with the aid of a loan insured... assistance. (b) Term for manufactured home parks. For manufactured home units or spaces in substantially...

Effect of ageing on the force development in tetanic contractions of motor units in rat medial gastrocnemius muscle.

PubMed

Łochyński, Dawid; Kaczmarek, Dominik; Krutki, Piotr; Celichowski, Jan

2010-09-01

The purpose of this study was to determine the effect of ageing on the rate of force generation of motor units, and the mechanical efficiency of contraction produced by a doublet discharge. The study was carried out on isolated motor units of rat medial gastrocnemius muscle of young (5-10 mo) and two groups of old (24-25 and 28-30 mo) Wistar rats. Motor units were classified into the fast fatigable (FF), fast resistant (FR) and slow (S) ones. The force output and rate of force development were determined for non-doublet unfused tetanic contractions evoked by a series of a constant-rate trains of pulses and corresponding doublet contractions starting with an initial brief interpulse interval of 5 ms, and for maximal tetanic contraction. In FF motor units the rate of force development and the force produced by the doublet discharge increased transiently at the age of 24-25 mo, while in S and FR motor units this increase was observed at the age of 28-30 mo. Age-related decrease in the rate of force development of skeletal muscle cannot be attributed to a decline in efficiency of force production by functioning motor units. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

48 CFR 204.7104-1 - Criteria for establishing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 204.7104-1 Criteria for establishing. Contract subline items provide flexibility to further identify..., manufacturer's part number, scope of work, description of services). (3) Unit prices and extended amounts. (i...

Cost-Plus-Percentage-of-Costs in Government Contracts

DTIC Science & Technology

1984-09-01

services to be performed under the contract. ASPR 3-405.6(a). cf. Martin-Marietta Corporation ASBCA No. 10062 , 65-2 BCA 14973. The granting of...371 F.2d 859 (1967); General Builders Supply Co. v. United States, 409 . F.2d 246 (1969); Martin-Marietta Corp., ASBCA 10062 , 65-2 BCA 1 4973 (1965...Inc., ASBCA 18730, 74-2 BCA 1 10,71.1 (1974). Kenimons-Wilson, Inc., ASBCA 16167, 72-2 BCA II 9689 (1972). Martin-Marietta Corp., ASBCA 10062 , 65-2

TECHNOLOGY SELECTION AND SYSTEM DESIGN, U.S. EPA ARSENIC DEMONSTRATION PROGRAM ROUND 1

EPA Science Inventory

Battelle, under a contract with the United States Environmental Protection Agency (EPA), is conducting full-scale demonstration studies on the removal of arsenic from drinking water supplies at 12 water treatment facilities throughout the United States. These demonstration studi...

Contracts for field projects and supporting research on enhanced oil recovery. Progress review number 83, quarter ending June 30, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Summaries of 41 research projects on enhanced recovery are presented under the following sections: (1) chemical flooding; (2) gas displacement; (3) thermal recovery; (4) geoscience technology; (5) resource assessment technology; and (6) reservoir classes. Each presentation gives the title of the project, contract number, research facility, contract date, expected completion data, amount of the award, principal investigator, and DOE program manager, and describes the objectives of the project and a summary of the technical progress.

24 CFR 983.303 - Reasonable rent.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 983.303 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... that affect market rent, such as: (i) The location, quality, size, unit type, and age of the contract... determined, including major differences between the contract units and comparable unassisted units. (3) The...

Small Business Innovations

NASA Technical Reports Server (NTRS)

1995-01-01

The PER-Force Handcontroller was originally developed for the International Space Station under a Johnson Space Center Small Business Innovation Research (SBIR) contract. Produced by Cybernet Systems Corporation, the unit is a force-reflecting system that manipulates robots or objects by "feel." The Handcontroller moves in six degrees of freedom, with real and virtual reality forces simulated by a 3-D molecular modeling software package. It is used in molecular modeling in metallurgy applications, satellite docking research, and in research on military unmanned ground vehicles.

48 CFR 225.802-70 - Contracts for performance outside the United States and Canada.

Code of Federal Regulations, 2010 CFR

2010-10-01

... outside the United States and Canada. 225.802-70 Section 225.802-70 Federal Acquisition Regulations System... States and Canada. Follow the procedures at PGI 225.802-70 when placing a contract requiring performance outside the United States and Canada. Also see Subpart 225.74, Defense Contractors Outside the United...

Motor unit behaviour and contractile changes during fatigue in the human first dorsal interosseus

PubMed Central

Carpentier, Alain; Duchateau, Jacques; Hainaut, Karl

2001-01-01

In 67 single motor units, the mechanical properties, the recruitment and derecruitment thresholds, and the discharge rates were recorded concurrently in the first dorsal interosseus (FDI) of human subjects during intermittent fatiguing contractions. The task consisted of isometric ramp-and-hold contractions performed at 50% of the maximal voluntary contraction (MVC). The purpose of this study was to examine the influence of fatigue on the behaviour of motor units with a wide range of activation thresholds. For low-threshold (< 25% MVC) motor units, the mean twitch force increased with fatigue and the recruitment threshold either did not change or increased. In contrast, the twitch force and the activation threshold decreased for the high-threshold (> 25% MVC) units. The observation that in low-threshold motor units a quick stretch of the muscle at the end of the test reset the unit force and recruitment threshold to the prefatigue value suggests a significant role for fatigue-related changes in muscle stiffness but not twitch potentiation or motor unit synchronization. Although the central drive intensified during the fatigue test, as indicated by an increase in surface electromyogram (EMG), the discharge rate of the motor units during the hold phase of each contraction decreased progressively over the course of the task for motor units that were recruited at the beginning of the test, especially the low-threshold units. In contrast, the discharge rates of newly activated units first increased and then decreased. Such divergent behaviour of low- and high-threshold motor units could not be individually controlled by the central drive to the motoneurone pool. Rather, the different behaviours must be the consequence of variable contributions from motoneurone adaptation and afferent feedback from the muscle during the fatiguing contraction. PMID:11483719

Toward understanding genotype x environment interactions in black raspberry (Rubus occidentalis L.)

USDA-ARS?s Scientific Manuscript database

Over the last 75 years, the black raspberry industry in the United States has undergone a slow but steady contraction because of a lack of adapted, disease resistant cultivars. Recent research about the health benefits of a diet rich in polyphenolics, and black raspberries in particular, has led to ...

Identification of Mutations in a Candidate Dengue 4 Vaccine Strain 341750 PDK20 and Construction of a Full-Length eDNA Clone of the PDK20 Vaccine Candidate

DTIC Science & Technology

2010-01-01

comply with a collection of information if it does not display a currently valid OMB control number . 1. REPORT DATE OCT 2009 2. REPORT TYPE 3. DATES...construction of a full-length eDNA clone of the PDK20 vaccine candidate 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Medical Research Center,Infectious

Species Composition, Larval Habitats, Seasonal Occurrence and Distribution of Potential Malaria Vectors and Associated Species of Anopheles (Diptera: Culicidae) from the Republic of Korea

DTIC Science & Technology

2010-02-17

Republic of Korea 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR (S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT...both organizations. The opinions and assertions contained herein are those of the authors and are not to be construed as official or reflecting the...views of the Department of the Army or the Department of Defense. Author details 1Division of Entomology, Walter Reed Army Institute of Research, Silver

NASA's university program: Active grants and research contracts, fiscal year 1975

NASA Technical Reports Server (NTRS)

1975-01-01

Active university research projects for Fiscal Year 1975 are reported by state, and foreign country. Cross indexes by: (1) grant/contract number; (2) field of science and engineering; (3) technical officer location; and (4) RTOP are included.

Single phase space laundry development

NASA Technical Reports Server (NTRS)

Colombo, Gerald V.; Putnam, David F.; Lunsford, Teddie D.; Streech, Neil D.; Wheeler, Richard R., Jr.; Reimers, Harold

1993-01-01

This paper describes a newly designed, 2.7 Kg (6 pound) capacity, laundry machine called the Single Phase Laundry (SPSL). The machine was designed to wash and dry crew clothing in a micro-gravity environment. A prototype unit was fabricated for NASA-JSC under a Small Business Innovated Research (SBIR) contract extending from September 1990 to January 1993. The unit employs liquid jet agitation, microwave vacuum drying, and air jet tumbling, which was perfected by KC-135 zero-g flight testing. Operation is completely automated except for loading and unloading clothes. The unit uses about 20 percent less power than a conventional household appliance.

24 CFR 891.705 - Project assistance contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... for an assisted unit (or residential space in a group home) that is leased to an eligible family is equal to the difference between the contract rent for the unit (or pro rata share of the contract rent in a group home) and the tenant rent payable by the family. (2) Payments to the Borrower for vacant...

Building the Case Toward a Definitive Clinical Trial: Saline Versus Plasma-Lyte

DTIC Science & Technology

2014-04-01

Plasma-Lyte* 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Chung K. K., Dubick M. A., 5d. PROJECT NUMBER 5e. TASK...NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) United States Army Institute of Surgical Research, JBSA Fort Sam...Hosuton, TX 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11

13 CFR 127.503 - When is a contracting officer authorized to restrict competition under this part?

Code of Federal Regulations, 2013 CFR

2013-01-01

... be made at fair market prices. This requirement does not preclude a contracting officer from making... reasonable expectation based on market research that: (1) Two or more EDWOSBs will submit offers for the... reasonable expectation based on market research that: (1) Two or more WOSBs will submit offers (this includes...

17 CFR Appendix A to Part 40 - Guideline No. 1

Code of Federal Regulations, 2011 CFR

2011-04-01

... trading unit 7. Delivery pack or composition of delivery units 8. Delivery instrument (e.g., warehouse... specifically requested, such additional evidence, information or data relating to whether the contract meets... (4) As specifically requested, such additional evidence, information or data relating to whether the...

Research pressure instrumentation for NASA Space Shuttle main engine, modification no. 5

NASA Technical Reports Server (NTRS)

Anderson, P. J.; Nussbaum, P.; Gustafson, G.

1984-01-01

The purpose of Modification No. 5 of this contract is to expand the scope of work (Task C) of this research study effort to develop pressure instrumentation for the SSME. The objective of this contract (Task C) is to direct Honeywell's Solid State Electronics Division's (SSED) extensive experience and expertise in solid state sensor technology to develop prototype pressure transducers which are targeted to meet the SSME performance design goals and to fabricate, test and deliver a total of 10 prototype units. SSED's basic approach is to effectively utilize the many advantages of silicon piezoresistive strain sensing technology to achieve the objectives of advanced state-of-the-art pressure sensors in terms of reliability, accuracy and ease of manufacture. More specifically, integration of multiple functions on a single chip is the key attribute of this technology which will be exploited during this research study.

An Analysis of Implementing a Rental Policy within the DoD’s Military Family Housing Program

DTIC Science & Technology

1994-06-01

801 authorizes the government to contract with local businesses for family housing units built to service standards. Under this program the government...housing." [Ref. 4:p.1] DMRD 910 was not approved. 2. DMRD 966: Operating MFH as a Business Enterprise The next DMRD that addressed military family ... business -like manner are: 1. F-using managers would obtain control of their staffing, purchasing and increased contracting authority. Managers could

Isometric contractions of motor units and immunohistochemistry of mouse soleus muscle.

PubMed Central

Lewis, D M; Parry, D J; Rowlerson, A

1982-01-01

1. Isometric contractions of motor units, isolated functionally by ventral root splitting in vivo, were recorded from mouse soleus muscle. 2. Motor unit tensions varied over a narrow symmetrical range and averaged 4.7% of whole muscle tension, corresponding to twenty-one motor units per muscle. 3. There was considerable variation between muscles in isometric twitch times-to-peak and even greater variation for the motor units. The distribution of motor unit times-to-peak was apparently unimodal and could be fitted by a single normal population. A slightly better fit was, however, obtained with two normal populations, as suggested by the histochemistry. 4. Twitch time-to-peak decreased in proportion to axonal conduction velocity in individual animals. The whole population of motor units could be fitted by a linear relation between time-to-peak and the reciprocal of conduction time in the motor axon. Motor unit tension was also linearly related to the reciprocal of conduction time. 5. Histochemistry showed clear division between Type I and Type IIa fibres. Type I fibres reacted strongly with antibody against slow myosin of cat soleus muscle; Type IIa gave a reaction no stronger than the background. The division was as clear as in the cat or rat. Images Fig. 2 Plate 1 PMID:7050345

Test and Evaluation Enhancements for Cognitive Radio Technologies

DTIC Science & Technology

2015-05-13

SECURITY CLASSIFICATION OF: This document serves as the final report for the Department of Defense (DoD) Research and Education Program for...report will described the instrumentation and the integration into the academic and research programs . All instrumentation has been procured, delivered...UNIT NUMBER 5c. PROGRAM ELEMENT NUMBER 5b. GRANT NUMBER 5a. CONTRACT NUMBER Form Approved OMB NO. 0704-0188 3. DATES COVERED (From - To) - UU UU UU UU

24 CFR 983.203 - HAP contract information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false HAP contract information. 983.203... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Housing Assistance Payments Contract § 983.203 HAP contract information. The HAP contract must specify: (a) The total number of contract units by number of bedrooms; (b...

Characteristic changes of motor unit activity in hip joint flexor muscles during voluntary isometric contraction during water immersion.

PubMed

Sugajima, Y; Mitarai, G; Koeda, M; Moritani, T

1996-06-01

The effect of whole body water immersion on the recruitment order of hip flexor motor units was investigated in 11 male subjects. Intramuscular spike potentials were recorded, with fine bipolar wire electrodes, from the iliopsoas, the sartorius, the rectus femoris and the tensor fasciae latae during voluntary isometric contraction while the subjects were standing erect with the hip on the test side flexed to 60 degrees and the knee flexed to 120 degrees . Data were analysed by measuring the recruitment threshold in slow ramp contraction and by a computer-aided amplitude-frequency histogram of the spike potentials during short sustained contraction. The motor units were classified as low-amplitude units if they delivered spike potentials of less than 0.5 mV and high-amplitude units if the spike potentials exceeded 0.5 mV. In the ramp experiments, exposure to water immersion gave rise to a sudden increase in the recruitment thresholds of the low-amplitude units in all muscles, while in the recruitment thresholds of the high-amplitude units, the alterations differed among the muscles. The thresholds in the rectus femoris and tensor fasciae latae increased in the same direction as those of the low-amplitude units, while those in the iliopsoas and sartorius decreased in the opposite direction. The amplitude-frequency histograms clearly indicated that these different alterations occurred in all subjects, without exception. We concluded that unloading induced by water immersion changed the recruitment order of motor units during isometric contraction in the iliopsoas and sartorius, facilitating the recruitment of their larger motor units.

76 FR 67425 - Availability of the Fiscal Year 2010 United States Special Operations Command (USSOCOM) Inventory...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-01

... Special Operations Command (USSOCOM) Inventory List of Contracts for Services; Correction AGENCY: United States Special Operations Command (USSOCOM), Department of Defense (DoD). ACTION: Notice of availability... Fiscal Year 2010 United States Special Operations Command (USSOCOM) Inventory List of Contracts for...

36 CFR 223.44 - Collection rights on contracts involved in transfer of purchase credit.

Code of Federal Regulations, 2011 CFR

2011-07-01

... FOREST PRODUCTS, AND FOREST BOTANICAL PRODUCTS Timber Sale Contracts Contract Conditions and Provisions... the United States in connection with the implementation of this regulation, contract provisions shall...

Adjustments in motor unit properties during fatiguing contractions after training.

PubMed

Vila-Chã, Carolina; Falla, Deborah; Correia, Miguel Velhote; Farina, Dario

2012-04-01

The objective of the study was to investigate the effect of strength and endurance training on muscle fiber membrane properties and discharge rates of low-threshold motor units of the vasti muscles during fatiguing contractions. Twenty-five sedentary healthy men (age (mean ± SD) = 26.3 ± 3.9 yr) were randomly assigned to one of three groups: strength training, endurance training, or a control group. Conventional endurance and strength training was performed 3 d·wk⁻¹, during a period of 6 wk. Motor unit conduction velocity and EMG amplitude of the vastus medialis obliquus and lateralis muscles and biceps femoris were measured during sustained isometric knee extensions at 10% and 30% of the maximum voluntary contraction before and immediately after training. After 6 wk of training, the reduction in motor unit conduction velocity during the sustained contractions at 30% of the maximum voluntary force occurred at slower rates compared with baseline (P < 0.05). However, the rate of decrease was lower after endurance training compared with strength training (P < 0.01). For all groups, motor unit discharge rates declined during the sustained contraction (P < 0.001), and their trend was not altered by training. In addition, the biceps femoris-vasti coactivation ratio declined after the endurance training. Short-term strength and endurance training induces alterations of the electrophysiological membrane properties of the muscle fiber. In particular, endurance training lowers the rate of decline of motor unit conduction velocity during sustained contractions more than strength training.

Highlights of L011.

DTIC Science & Technology

1977-08-03

AD—A OQ 15 CALIFORNIA UN I V SANTA CRUZ INFORMATION SCIENCES FIG 9.’2 HIGHLIGHTS OF LO11.(U) ~~~ LASS ~~~~~ TR— 77—8—OO5 H MCKEEMAN EN D...EA & WORK UNIT NUMBERS Board of Studies in Information Sciences - . University of Californiav ~~~~~~~~ • I Santa Cruz, Ca1ifnrn(~ 9S~ f LL - II. C O...Office of Naval Research contract NOOO1~ —76 C O682.* .~~~~ .. 3. The Board of Studies in InforMation Sciences, UCSCe~~~~ ~~~~~ 00 ~~ ~~~~~ ifl ,’jIIfl

Contracting Data Analysis: Assessment of Government-Wide Trends

DTIC Science & Technology

2017-03-01

GAO-17-244SP United States Government Accountability Office (This Page Intentionally Left Blank) United States Government Accountability ...2015, accounting for almost 40 percent of the government’s discretionary spending. Because spending on contracts consumes a large portion of the...year 2015, federal agencies obligated over $430 billion through contracts for goods and services, accounting for almost 40 percent of the

48 CFR 35.010 - Scientific and technical reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.010 Scientific and technical reports. (a) R&D contracts shall require contractors to furnish scientific and technical reports... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Scientific and technical...

48 CFR 35.010 - Scientific and technical reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.010 Scientific and technical reports. (a) R&D contracts shall require contractors to furnish scientific and technical reports... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Scientific and technical...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

48 CFR 27.303 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

...)(1) Insert a patent rights clause in all solicitations and contracts for experimental, developmental... contracts for construction work or architect-engineer services that include— (i) Experimental, developmental, or research work; (ii) Test and evaluation studies; or (iii) The design of a Government facility that...

48 CFR 35.010 - Scientific and technical reports.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Scientific and technical... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.010 Scientific and technical reports. (a) R&D contracts shall require contractors to furnish scientific and technical reports...

48 CFR 35.010 - Scientific and technical reports.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Scientific and technical... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.010 Scientific and technical reports. (a) R&D contracts shall require contractors to furnish scientific and technical reports...

48 CFR 35.010 - Scientific and technical reports.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Scientific and technical... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.010 Scientific and technical reports. (a) R&D contracts shall require contractors to furnish scientific and technical reports...

7. SHEET 1, CONTROL HOUSE FOR DRY DOCK. United Engineering ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. SHEET 1, CONTROL HOUSE FOR DRY DOCK. United Engineering Company Ltd., Alameda Shipyard, Ship Repair Facilities, Office Building. Plans, elevations, sections, details. John Hudspeth, Architect, at foot of Main Street, Alameda, Calif. Sheet no. 1 of 2 sheets, Plan no. 10,507. Various scales. January 4, 1943, last revised 1/28/43. U.S. Navy, Bureau of Yards & Docks, Contract no. bs 76. Approved for construction October 9, 1943. blueprint - United Engineering Company Shipyard, Control House for Dry Dock, 2900 Main Street, Alameda, Alameda County, CA

Borehole X-Ray Fluorescence Spectrometer (XRFS): User’s Manual, Software Description, and Performance Report

DTIC Science & Technology

2007-12-01

and Performance Report built by APL-UW under a NASA contract from the Langley Research Center Technical Report APL-UW TR 0703 December 2007...Approved for public release; distribution is unlimited. W.C. Kelliher1, I.A. Carlberg1, W.T. Elam2, and E. Willard-Schmoe2 1NASA Langley Research ...Procurement, Research & Projects Contracting Branch Mail Stop 126 9B Langley Blvd. Hampton, VA 23681-2199 APL-UW TR 0703 DP4 User Manual D1.doc, 4/6/05

22 CFR 221.43 - Governing law.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Governing law. 221.43 Section 221.43 Foreign... Administration § 221.43 Governing law. This Guarantee shall be governed by and construed in accordance with the laws of the United States of America governing contracts and commercial transactions of the United...

NASA and Orbital ATK CRS-7 Prelaunch News Conference

NASA Image and Video Library

2017-04-17

In the NASA Kennedy Space Center's Press Site auditorium, agency and industry leaders brief the media about the upcoming launch of Orbital ATK’s seventh commercial resupply services mission to the International Space Station. Orbital ATK has contracted with United Launch Alliance for its Atlas V rocket for the launch service which will lift off from Space Launch Complex-41 at Cape Canaveral Air Force Station in Florida. Under NASA’s first Commercial Resupply Services contract, more than 7,600 pounds of science research, crew supplies and hardware will be delivered to the orbiting laboratory in support of the crew members. Briefing participants: -George Diller, NASA Communications -Joel Montalbano, Deputy Manager, NASA International Space Station Program -Vern Thorp, Program Manager for Commercial Missions, United Launch Alliance -Frank Culbertson, President, Space Systems Group, Orbital ATK -Tara Ruttley, Associate Program Scientist, JSC -David Craft, Weather Officer, 45th Weather Squadron

Tachykinin antagonist FK224 inhibits neurokinin A-, substance P- and capsaicin-induced human bronchial contraction.

PubMed

Honda, I; Kohrogi, H; Yamaguchi, T; Hamamoto, J; Hirata, N; Iwagoe, H; Fujii, K; Goto, E; Ando, M

1997-01-01

To determine the roles of endogenously released tachykinins (substance P [SP] and neurokinin A [NKA]) in the human bronchial tissues, we studied the effects of tachykinin antagonist FK224 on bronchial smooth muscle contraction induced by SP, NKA and capsaicin in an organ bath. FK224 (10(-6) M and 10(-5) M, respectively) significantly inhibited NKA-induced contraction and 10(-5) M FK224 shifted the dose-response curve to more than one log unit higher concentration. Because SP- and capsaicin-induced contractions were small, we pretreated the tissues with the neutral endopeptidase inhibitor phosphoramidon (10(-5) M), which inhibits degradation of exogenous tachykinins in order to potentiate the contractions. FK224 (10(-5) M) significantly inhibited SP-induced contraction and it shifted the dose-response curves to about one log unit higher concentration. FK224 (10(-5) M) also significantly inhibited capsaicin-induced contraction and it shifted the dose-response curves to more than one log unit higher concentration. In contrast, FK224 (10(-5) M) did not affect on acetylcholine-, histamine-, and leukotriene D4-induced contraction. These results suggest that FK224 is a tachykinin receptor antagonist in the human bronchial smooth muscle, and that capsaicin-induced contraction is due to endogenously released tachykinin-like substances in the human bronchus.

77 FR 54937 - International Mail Postal Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-06

... United States for recycling, refurbishment, repair, or value-added processing. Notice at 5. \\3\\ The IBRS... to take effect 1 day later, on September 15, 2012, for a period of 1 year, unless terminated earlier...

Muscle spindle response at the onset of isometric voluntary contractions in man. Time difference between fusimotor and skeletomotor effects

PubMed Central

Vallbo, Å. B.

1971-01-01

1. Impulses in single muscle afferents were recorded from the median nerves of waking human subjects with percutaneously inserted tungsten needle electrodes. During isometric voluntary contractions, unitary discharges were analysed from muscle spindle endings in the wrist and finger flexor muscles and the electromyographic activity from these muscles was recorded simultaneously. 2. When the subject activated the muscle portion in which a spindle was located, the afferent discharge increased in spite of the mechanical unloading effects of the skeletomotor contraction indicating a concomitant fusimotor activation. This was valid for slowly rising contractions as well as small fast rising twitches. 3. The time of onset of spindle acceleration was determined in relation to the time of onset of the electromyographic activity for thirty-one units studied altogether in more than seven hundred contractions. It was found that spindle acceleration regularly occurred after the onset of the electromyographic activity. 4. There was a considerable variation from one test to the other, for the individual units, with regard to the exact time of onset of spindle acceleration, although spindle acceleration occurred mostly within 0·5 sec after the onset of the electromyographic activity in sustained contractions and within 0·1 sec in small fast rising twitches. It was not possible to assess to what extent this variation was accounted for by variations in the mechanical unloading effects of the skeletomotor contraction or variations in the timing of the fusimotor outflow. 5. For many units, spindle acceleration did not occur until 10-50 msec after the onset of the skeletomotor contraction. This time is of the same order of magnitude as the time difference in latency from the spinal cord to the recording points in the two systems, as estimated from reasonable assumptions. 6. It was concluded that the fusimotor system does not participate in the initiation of voluntary contractions in man, but that the skeletomotor activity is initiated by descending impulses from supraspinal structures and their effects on the neuronal organization within the spinal cord. 7. The fact that fusimotor activation occurs also in very small and short lasting twitches, when spindle acceleration must have a negligible influence on the skeletomotor outflow, suggests that the fusimotor and the skeletomotor systems are rigidly co-activated in voluntary contractions. 8. The finding that spindle acceleration does not occur until 10-50 msec after the onset of the electromyographic activity suggests that there is an approximately simultaneous onset of the fusimotor and the skeletomotor outflows from the spinal cord. PMID:4256547

The vastus lateralis neuromuscular activity during all-out cycling exercise.

PubMed

Bercier, Stephane; Halin, Renaud; Ravier, Philippe; Kahn, Jean-Francois; Jouanin, Jean-Claude; Lecoq, Anne-Marie; Buttelli, Olivier

2009-10-01

The objective of this work was to study modifications in motor control through surface electromyographic (sEMG) activity during a very short all-out cycling exercise. Twelve male cyclists (age 23+/-4 years) participated in this study. After a warm-up period, each subject performed three all-out cycling exercises of 6s separated by 2 min of complete rest. This protocol was repeated three times with a minimum of 2 days between each session. The braking torque imposed on cycling motion was 19 Nm. The sEMG of the vastus lateralis was recorded during the first seven contractions of the sprint. Time-frequency analysis of sEMG was performed using continuous wavelet transform. The mean power frequency (MPF, qualitative modifications in the recruitment of motor units) and signal energy (a quantitative indicator of modifications in the motor units recruitment) were computed for the frequency range 10-500 Hz. sEMG energy increased (P0.05) between contraction number 1 and 2, decreased (P < or =0.05) between contraction number 2 and 3 then stabilized between contraction number 3 and 7 during the all-out test. MPF increased (P < or =0.05) during the all-out test. This increase was more marked during the first two contractions. The decrease in energy and the increase in the sEMG MPF suggest a large spatial recruitment of motor units (MUs) at the beginning of the sprint followed by a preferential recruitment of faster MUs at the end of the sprint, respectively.

24 CFR 206.131 - Contract rights and obligations for mortgages on individual dwelling units in a condominium.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Contract rights and obligations for... MORTGAGE INSURANCE Contract Rights and Obligations Condominiums § 206.131 Contract rights and obligations...] Termination of Insurance Contract ...

13 CFR 127.503 - When is a contracting officer authorized to restrict competition under this part?

Code of Federal Regulations, 2010 CFR

2010-01-01

... reasonable expectation based on market research that: (1) Two or more EDWOSBs will submit offers for the... requirements. If market research indicates that the criteria in paragraph (a) are not met for restricting...; and (2) The contracting officer has a reasonable expectation based on market research that— (i) Two or...

13 CFR 127.503 - When is a contracting officer authorized to restrict competition under this part?

Code of Federal Regulations, 2011 CFR

2011-01-01

... has a reasonable expectation based on market research that: (1) Two or more EDWOSBs will submit offers...) WOSB requirements. If market research indicates that the criteria in paragraph (a) are not met for...; and (2) The contracting officer has a reasonable expectation based on market research that— (i) Two or...

Defining Acquisition and Contracting Terms Associated with Contract Administration

DTIC Science & Technology

1990-09-01

for being such a dedicated scholar. You motivated me to study and as a result I have obtained my goals. May we be as successful in all our future...Assumptions and Scope of the Research ............ 1-8 1.7 Organization of the Study ...... ................ 1-9 II. Literature Review...Abstract The purpose of this study was to synthesize definitions for 20 terms associated with contract administration. To adequately accomplish this

Advanced Stirling Radioisotope Generator Engineering Unit 2 (ASRG EU2) Final Assembly

NASA Technical Reports Server (NTRS)

Oriti, Salvatore M.

2015-01-01

NASA Glenn Research Center (GRC) has recently completed the assembly of a unique Stirling generator test article for laboratory experimentation. Under the Advanced Stirling Radioisotope Generator (ASRG) flight development contract, NASA GRC initiated a task to design and fabricate a flight-like generator for in-house testing. This test article was given the name ASRG Engineering Unit 2 (EU2) as it was effectively the second engineering unit to be built within the ASRG project. The intent of the test article was to duplicate Lockheed Martin's qualification unit ASRG design as much as possible to enable system-level tests not previously possible at GRC. After the cancellation of the ASRG flight development project, the decision was made to continue the EU2 build, and make use of a portion of the hardware from the flight development project. GRC and Lockheed Martin engineers collaborated to develop assembly procedures, leveraging the valuable knowledge gathered by Lockheed Martin during the ASRG development contract. The ASRG EU2 was then assembled per these procedures at GRC with Lockheed Martin engineers on site. The assembly was completed in August 2014. This paper details the components that were used for the assembly, and the assembly process itself.

Hardware Assessment in Support of the Dynamic Power Convertor Development Effort

NASA Technical Reports Server (NTRS)

Wilson, Scott D.; Oriti, Sal M.; Schifer, Nicholas A.

2017-01-01

Stirling Radioisotope Power Systems (RPS) are being developed by NASA's RPS Program in collaboration with the U.S. Department of Energy (DOE). Efforts ranging from 2001 to 2015 enabled development of the Technology Demonstration Convertor (TDC) for use in the 110-watt Stirling Radioisotope Generator (SRG-110) and the Advanced Stirling Convertor (ASC) for use in the Advanced Stirling Radioisotope Generator (ASRG). The DOE selected Lockheed Martin Space Systems Company (LMSSC) as the system integration contractor for both flight development efforts. The SRG-110 housed two TDCs fabricated by Infinia and resulted in the production of 16x demonstration units and 2x engineering units. The project was redirected in 2006 to make use of a more efficient and lower mass ASCs under development by Sunpower Inc. The DOE managed the flight contract with LMSSC and subcontractor Sunpower Inc. from 2007 to 2013 to build the ASRG, with support from NASA Glenn Research Center (GRC). Sunpower Inc. held two parallel contracts to produce ASCs, one with Lockheed Martin to produce ASC-F flight units and one with GRC for the production of ASC-E3 engineering unit pathfinders that were used to refine the flight design and production processes. The DOE initiated termination of the ASRG contract in late 2013. After ASRG had ended, GRC completed characterization testing of the ASRG Engineering Unit #2 (EU2) and the GRC contract with Sunpower was also completed. The NASA RPS Program Office has recently initiated a new Dynamic Power Conversion development effort which includes the potential maturation of Stirling, Brayton, and Rankine power convertors for the next generation of RPS. The effort started with the request for proposal and review of submits. Contracts are anticipated for release in 2017 and will initially focus on a design phase prior to fabrication and testing. This new effort will focus on robustness in addition to high efficiency, specific power, and reliability. Also, some requirements introduced during the ASRG contract have also been included in the new effort, such as constant lateral loading. Due to the focus on robustness and new requirements relative to the older TDC design, the Stirling Cycle Development Project has initiated an assessment of government owned hardware to help inform requirements evolution and evaluation of future designs. While lessons learned from the ASRG flight development project have been taken into consideration, the evaluation of the TDC design had not been completed for some existing environments or relatively new requirements. To further assess the TDC design, a series of tasks were initiated to evaluate degradation for units that have operated unattended for over 105,000 hours, demonstrate robustness to a random vibration environment, characterize and evaluate performance for varying lateral load profiles. The status for each task are described.

Recruitment order of motor units in human vastus lateralis muscle is maintained during fatiguing contractions.

PubMed

Adam, Alexander; De Luca, Carlo J

2003-11-01

Motor-unit firing patterns were studied in the vastus lateralis muscle of five healthy young men [21.4 +/- 0.9 (SD) yr] during a series of isometric knee extensions performed to exhaustion. Each contraction was held at a constant torque level, set to 20% of the maximal voluntary contraction at the beginning of the experiment. Electromyographic signals, recorded via a quadrifilar fine wire electrode, were processed with the precision decomposition technique to identify the firing times of individual motor units. In repeat experiments, whole-muscle mechanical properties were measured during the fatigue protocol using electrical stimulation. The main findings were a monotonic decrease in the recruitment threshold of all motor units and the progressive recruitment of new units, all without a change of the recruitment order. Motor units from the same subject showed a similar time course of threshold decline, but this decline varied among subjects (mean threshold decrease ranged from 23 to 73%). The mean threshold decline was linearly correlated (R2 >or= 0.96) with a decline in the elicited peak tetanic torque. In summary, the maintenance of recruitment order during fatigue strongly supports the notion that the observed common recruitment adaptations were a direct consequence of an increased excitatory drive to the motor unit pool. It is suggested that the increased central drive was necessary to compensate for the loss in force output from motor units whose muscle fibers were actively contracting. We therefore conclude that the control scheme of motor-unit recruitment remains invariant during fatigue at least in relatively large muscles performing submaximal isometric contractions.

75 FR 32638 - Defense Federal Acquisition Regulation Supplement; Contract Authority for Advanced Component...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

... Prototype Units (DFARS Case 2009-D034) AGENCY: Defense Acquisition Regulations System, Department of Defense... Component Development or Prototype Units.'' Section 819 is intended to prevent a contract for new technology... development of advanced components or the procurement of prototype units. To do so, section 819 places...

48 CFR 22.807 - Exemptions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., are not exempt.) (2) Work outside the United States. Contracts are exempt from the requirements of E.O. 11246 for work performed outside the United States by employees who were not recruited within the United... work on or under the contract. (4) Work on or near Indian reservations. It shall not be a violation of...

Electromechanical Actuation Feasibility Study

DTIC Science & Technology

1976-05-01

FORMA11ON SLRVicE U. S. DPMfmft1 OF COMMOM AmR 703CR IIGRT DYNAM1U8 LABORATOY AMR 706C YST TM- COMMAND\\ ~WRIGUT-PATTEAWNk AIR POW= RASL OHIO 45M8...AMIE AND0 ACGRIESS 52 RIEPOR01T DATE Air Force Flight Dy-namics Labcratory May 1976 AFSC/AFWAL, United States Air Force 11 sNjsBsIm OF PAGIES Wright... Air Force under Contract Fý3615-75-C-305, Electronechanical Actuation Feasibility Study. The contract was aaministereu by the Air Force Flioht Dynamics

Evaluating an Air Force Pilot Retention Bonus

DTIC Science & Technology

1989-12-01

pay from the 1985 United Airline contract and the 1987 Future Aviation Professionals of America ( FAPA ) projection of airline pay (see Appendix C...COMMERCIAL AIRLINE PAY Table C-1. Two Alternative Airline Pay Schedules Yrs W/Airline" Unitedb FAPAe 0 S25,197 $22,000 1 28,801 36,000 2 37,197 40,000 3...through 1987 as called for by contract. cFAPA: 1987 FAPA projection of airline pay. 37 | I MO APPENDIX D. OFFICER COMPENSATION AND PILOT INVENTORY

Agreement between the Board of Trustees of the California State University and the California Faculty Association, Unit 3--Faculty, August 16, 1983-June 30, 1986 and New Contract Language Changes to Agreement, July 1, 1984-June 30, 1986.

ERIC Educational Resources Information Center

California State Postsecondary Education Commission, Sacramento.

The collective bargaining agreement between California State University (CSU) Board of Trustees and the California Faculty Association (CFA) for the period covering August 16, 1983-June 30, 1986 is presented. New contract language changes to the agreement for July 1, 1984-June 30, 1986 are also presented. This American Association of University…

Evaluation of the Regional Educational Laboratories. Interim Report. NCEE 2013-4014

ERIC Educational Resources Information Center

Carlson, Elaine; Scott, Jenna; Zhang, Xiaodong; Gutmann, Babette; Sinclair, Beth

2013-01-01

The Regional Educational Laboratories (RELs) are a networked system of 10 organizations that serve the educational needs of 10 designated regions across the United States and its territories. The U.S. Department of Education (ED) is authorized by the Education Sciences Reform Act (ESRA) to award contracts to 10 RELs to support applied research,…

Regional Comparative Advantage for Woody Biofuels Production

Treesearch

Timothy M. Young; Donald G. Hodges; Robert C. Abt; Andy J. Hartsell; James H. Perdue

2009-01-01

The economic availability of woody biomass for the southeastern United States is summarized in this final report for the U.S. Department of Transportation, Southeastern Sun Grant Center research contract R11-0515-016 as administered by the University of Tennessee. Georeferenced economic supply curves (marginal cost curves) for woody biomass producers’ for the 13...

Forecasting resource-allocation decisions under climate uncertainty: fire suppression with assessment of net benefits of research

Treesearch

Jeffrey P. Prestemon; Geoffrey H. Donovan

2008-01-01

Making input decisions under climate uncertainty often involves two-stage methods that use expensive and opaque transfer functions. This article describes an alternative, single-stage approach to such decisions using forecasting methods. The example shown is for preseason fire suppression resource contracting decisions faced by the United States Forest Service. Two-...

Integrating Traumatic Brain Injury Model Systems Data into the Federal Interagency Traumatic Brain Injury Research Informatics Systems

DTIC Science & Technology

2016-10-01

Traumatic Brain Injury Research Informatics Systems 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-14-1-0564 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...AWARD NUMBER: W81XWH-14-1-0564 TITLE: Integrating Traumatic Brain Injury Model Systems Data into the Federal Interagency Traumatic Brain Injury...Research Informatics Systems PRINCIPAL INVESTIGATOR: Cynthia Harrison-Felix, PhD CONTRACTING ORGANIZATION: Craig Hospital Englewood, CO 80113

7 CFR 1484.35 - Must Cooperators follow specific contracting procedures?

Code of Federal Regulations, 2011 CFR

2011-01-01

..., challenges, or other disputes based on contracts entered into by the Cooperator. Neither FAS nor any other agency of the United States Government or any official or employee of FAS or the United States Government...

7 CFR 1484.35 - Must Cooperators follow specific contracting procedures?

Code of Federal Regulations, 2014 CFR

2014-01-01

... disputes based on contracts entered into by the Cooperator. Neither FAS nor any other agency of the United States Government or any official or employee of FAS or the United States Government has any obligation...

7 CFR 1484.35 - Must Cooperators follow specific contracting procedures?

Code of Federal Regulations, 2012 CFR

2012-01-01

... disputes based on contracts entered into by the Cooperator. Neither FAS nor any other agency of the United States Government or any official or employee of FAS or the United States Government has any obligation...

7 CFR 1484.35 - Must Cooperators follow specific contracting procedures?

Code of Federal Regulations, 2013 CFR

2013-01-01

... disputes based on contracts entered into by the Cooperator. Neither FAS nor any other agency of the United States Government or any official or employee of FAS or the United States Government has any obligation...

Manipulation of the Phase-Amplitude Coupling Factor in Quantum Nanostructure Based Devices for On-Chip Chirp Compensation and Low-Cost Applications

DTIC Science & Technology

2014-11-17

Compensation and Low -Cost Applications Frederic Grillot CTRE NAT DE LA RECHERCHE SCIENTIFIQUE 74, RUE DE PARIS CENTRE AFFAIRES OBERTHUR RENNES, 35000...of Scientific Research European Office of Aerospace Research and Development Unit 4515, APO AE 09421-4515 Distribution Statement A: Approved for...Amplitude Coupling Factor in Quantum Nanostructure Based Devices for On-Chip Chirp Compensation and Low -Cost Applications 5a. CONTRACT NUMBER

Evaluation of higher order statistics parameters for multi channel sEMG using different force levels.

PubMed

Naik, Ganesh R; Kumar, Dinesh K

2011-01-01

The electromyograpy (EMG) signal provides information about the performance of muscles and nerves. The shape of the muscle signal and motor unit action potential (MUAP) varies due to the movement of the position of the electrode or due to changes in contraction level. This research deals with evaluating the non-Gaussianity in Surface Electromyogram signal (sEMG) using higher order statistics (HOS) parameters. To achieve this, experiments were conducted for four different finger and wrist actions at different levels of Maximum Voluntary Contractions (MVCs). Our experimental analysis shows that at constant force and for non-fatiguing contractions, probability density functions (PDF) of sEMG signals were non-Gaussian. For lesser MVCs (below 30% of MVC) PDF measures tends to be Gaussian process. The above measures were verified by computing the Kurtosis values for different MVCs.

48 CFR 52.248-1 - Value Engineering.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contract requirement and the proposed requirement, the comparative advantages and disadvantages of each, a... not rewardable under performance, design-to-cost (production unit cost, operating and support costs...

48 CFR 52.248-1 - Value Engineering.

Code of Federal Regulations, 2013 CFR

2013-10-01

... contract requirement and the proposed requirement, the comparative advantages and disadvantages of each, a... not rewardable under performance, design-to-cost (production unit cost, operating and support costs...

48 CFR 52.248-1 - Value Engineering.

Code of Federal Regulations, 2012 CFR

2012-10-01

... contract requirement and the proposed requirement, the comparative advantages and disadvantages of each, a... not rewardable under performance, design-to-cost (production unit cost, operating and support costs...

48 CFR 52.248-1 - Value Engineering.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contract requirement and the proposed requirement, the comparative advantages and disadvantages of each, a... not rewardable under performance, design-to-cost (production unit cost, operating and support costs...

48 CFR 52.248-1 - Value Engineering.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contract requirement and the proposed requirement, the comparative advantages and disadvantages of each, a... not rewardable under performance, design-to-cost (production unit cost, operating and support costs...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause. The contracting officer shall insert the clause at (TAR) 48 CFR 1252.235-70, Research Misconduct, in... Policy on Research Misconduct,” dated February 2002. ...

Electrically stimulated contractions of Vorticella convallaria

NASA Astrophysics Data System (ADS)

Kantha, Deependra; van Winkle, David

2009-03-01

The contraction of Vorticella convallaria was triggered by applying a voltage pulse in its host culturing medium. The 50V, 1ms wide pulse was applied across platinum wires separated by 0.7 cm on a microscope slide. The contractions were recorded as cines (image sequences) by a Phantom V5 camera (Vision Research) on a bright field microscope with 20X objective, with the image size of 256 pixels x 128 pixels at 7352 pictures per second. The starting time of the cines was synchronized with the starting of the electrical pulse. We recorded five contractions of each of 12 organisms. The cines were analyzed to obtain the initiation time, defined as the difference in time between the leading edge of the electrical pulse and the first frame showing zooid movement. From multiple contractions of same organism, we found the initiation time is reproducible. In comparing different organisms, we found the average initiation time of 1.73 ms with a standard deviation of 0.63 ms. This research is supported by the state of Florida (MARTECH) and Research Corporation.

Muscle strength at the trunk*.

PubMed

Smidt, G L; Amundsen, L R; Dostal, W F

1980-01-01

The purpose of this study was to determine the strength of trunk flexors and extensors in normal male subjects during isometric, concentric, and eccentric contractions. Subjects were tested in the sidelying position to minimize the effects of gravity. The pelvis and lower extremities were measured on a custom built force table (lowa Force Table). Muscle strength was expressed as a moment of force (external force times the moment arm) in Newton-meter (Nm) units. Greater Nm were registered in the muscle-lengthened position than in the muscle-shortened position for all isometric contractions. The Nm registered for eccentric contractions always exceeded the Nm registered for concentric contractions of the same muscle group. The Nm registered during contractions of trunk extensors always exceeded the values obtained during corresponding modes of contractions (isometric, eccentric, and concentric) of trunk flexors.J Orthop Sports Phys Ther 1980;1(3):165-170.

WAREHOUSE END FRAMING. United Engineering Company Ltd., Alameda Shipyard. Sections ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

WAREHOUSE END FRAMING. United Engineering Company Ltd., Alameda Shipyard. Sections at north and detail sections. No architect noted. Drawn by Penney. Plan no. 2-N-9 (U.E. Co. plan no. 10,523). Scales 1/4 inch and 1 inch to the foot. March 10, 1942, no revisions. U.S. Navy, Bureau of Yards & Docks, Contract no. bs 76, item no. 22A. Approved for construction October 9, 1943. blueprint - United Engineering Company Shipyard, Warehouse, 2900 Main Street, Alameda, Alameda County, CA

48 CFR 46.308 - Cost-reimbursement research and development contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... research and development contracts. 46.308 Section 46.308 Federal Acquisition Regulations System FEDERAL... research and development contracts. The contracting officer shall insert the clause at 52.246-8, Inspection of Research and Development—Cost-Reimbursement, in solicitations and contracts for research and...

48 CFR 46.308 - Cost-reimbursement research and development contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... research and development contracts. 46.308 Section 46.308 Federal Acquisition Regulations System FEDERAL... research and development contracts. The contracting officer shall insert the clause at 52.246-8, Inspection of Research and Development—Cost-Reimbursement, in solicitations and contracts for research and...

48 CFR 806.302-5 - Authorized or required by statute.

Code of Federal Regulations, 2010 CFR

2010-10-01

... to be associated with affiliated institutions), or with blood banks, organ banks, or research centers... authorities: (1) For contracts for orthopedic and prosthetic appliances and related services including research, cite 38 U.S.C. 8123. (38 U.S.C. 8123) (2) For contracts to purchase or sell merchandise...

48 CFR 806.302-5 - Authorized or required by statute.

Code of Federal Regulations, 2014 CFR

2014-10-01

... to be associated with affiliated institutions), or with blood banks, organ banks, or research centers... authorities: (1) For contracts for orthopedic and prosthetic appliances and related services including research, cite 38 U.S.C. 8123. (38 U.S.C. 8123) (2) For contracts to purchase or sell merchandise...

48 CFR 806.302-5 - Authorized or required by statute.

Code of Federal Regulations, 2013 CFR

2013-10-01

... to be associated with affiliated institutions), or with blood banks, organ banks, or research centers... authorities: (1) For contracts for orthopedic and prosthetic appliances and related services including research, cite 38 U.S.C. 8123. (38 U.S.C. 8123) (2) For contracts to purchase or sell merchandise...

48 CFR 806.302-5 - Authorized or required by statute.

Code of Federal Regulations, 2012 CFR

2012-10-01

... to be associated with affiliated institutions), or with blood banks, organ banks, or research centers... authorities: (1) For contracts for orthopedic and prosthetic appliances and related services including research, cite 38 U.S.C. 8123. (38 U.S.C. 8123) (2) For contracts to purchase or sell merchandise...

48 CFR 806.302-5 - Authorized or required by statute.

Code of Federal Regulations, 2011 CFR

2011-10-01

... to be associated with affiliated institutions), or with blood banks, organ banks, or research centers... authorities: (1) For contracts for orthopedic and prosthetic appliances and related services including research, cite 38 U.S.C. 8123. (38 U.S.C. 8123) (2) For contracts to purchase or sell merchandise...

48 CFR 32.410 - Findings, determination, and authorization.

Code of Federal Regulations, 2013 CFR

2013-10-01

... shall be supported by written findings (see 32.402(c)(1)(iii)). (b) The following is an example of the...), as applicable]. (6) The Contractor is a nonprofit (educational) (and) (research) institution, and the contract is for (experimental) (,) (research and development) work. (7) The contract is solely for the...

48 CFR 32.410 - Findings, determination, and authorization.

Code of Federal Regulations, 2011 CFR

2011-10-01

... shall be supported by written findings (see 32.402(c)(1)(iii)). (b) The following is an example of the...), as applicable]. (6) The Contractor is a nonprofit (educational) (and) (research) institution, and the contract is for (experimental) (,) (research and development) work. (7) The contract is solely for the...

48 CFR 32.410 - Findings, determination, and authorization.

Code of Federal Regulations, 2012 CFR

2012-10-01

... shall be supported by written findings (see 32.402(c)(1)(iii)). (b) The following is an example of the...), as applicable]. (6) The Contractor is a nonprofit (educational) (and) (research) institution, and the contract is for (experimental) (,) (research and development) work. (7) The contract is solely for the...

48 CFR 32.410 - Findings, determination, and authorization.

Code of Federal Regulations, 2010 CFR

2010-10-01

... shall be supported by written findings (see 32.402(c)(1)(iii)). (b) The following is an example of the...), as applicable]. (6) The Contractor is a nonprofit (educational) (and) (research) institution, and the contract is for (experimental) (,) (research and development) work. (7) The contract is solely for the...

48 CFR 32.410 - Findings, determination, and authorization.

Code of Federal Regulations, 2014 CFR

2014-10-01

... shall be supported by written findings (see 32.402(c)(1)(iii)). (b) The following is an example of the...), as applicable]. (6) The Contractor is a nonprofit (educational) (and) (research) institution, and the contract is for (experimental) (,) (research and development) work. (7) The contract is solely for the...

Advanced Stirling Convertor Development for NASA Radioisotope Power Systems

NASA Technical Reports Server (NTRS)

Wong, Wayne A.; Wilson, Scott D.; Collins, Josh

2015-01-01

Sunpower Inc.'s Advanced Stirling Convertor (ASC) initiated development under contract to the NASA Glenn Research Center and after a series of successful demonstrations, the ASC began transitioning from a technology development project to a flight development project. The ASC has very high power conversion efficiency making it attractive for future Radioisotope Power Systems (RPS) in order to make best use of the low plutonium-238 fuel inventory in the United States. In recent years, the ASC became part of the NASA and Department of Energy (DOE) Advanced Stirling Radioisotope Generator (ASRG) Integrated Project. Sunpower held two parallel contracts to produce ASCs, one with the DOE and Lockheed Martin to produce the ASC-F flight convertors, and one with NASA Glenn for the production of ASC-E3 engineering units, the initial units of which served as production pathfinders. The integrated ASC technical team successfully overcame various technical challenges that led to the completion and delivery of the first two pairs of flightlike ASC-E3 by 2013. However, in late fall 2013, the DOE initiated termination of the Lockheed Martin ASRG flight development contract driven primarily by budget constraints. NASA continues to recognize the importance of high-efficiency ASC power conversion for RPS and continues investment in the technology including the continuation of ASC-E3 production at Sunpower and the assembly of the ASRG Engineering Unit #2. This paper provides a summary of ASC technical accomplishments, overview of tests at Glenn, plans for continued ASC production at Sunpower, and status of Stirling technology development.

TASAR Certification and Operational Approval Requirements - Analyses and Results

NASA Technical Reports Server (NTRS)

Koczo, Stefan, Jr.

2015-01-01

This report documents the results of research and development work performed by Rockwell Collins in addressing the Task 1 objectives under NASA Contract NNL12AA11C. Under this contract Rockwell Collins provided analytical support to the NASA Langley Research Center (LaRC) in NASA's development of a Traffic Aware Strategic Aircrew Requests (TASAR) flight deck Electronic Flight Bag (EFB) application for technology transition into operational use. The two primary objectives of this contract were for Rockwell Collins and the University of Iowa OPL to 1) perform an implementation assessment of TASAR toward early certification and operational approval of TASAR as an EFB application (Task 1 of this contract), and 2) design, develop and conduct two Human-in-the-Loop (HITL) simulation experiments that evaluate TASAR and the associated Traffic Aware Planner (TAP) software application to determine the situational awareness and workload impacts of TASAR in the flight deck, while also assessing the level of comprehension, usefulness, and usability of the features of TAP (Task 2 of this contract). This report represents the Task 1 summary report. The Task 2 summary report is provided in [0].

Annual Technical Report to the Office of Naval Research.

DTIC Science & Technology

1981-11-01

7 A A1 208 MICHIGAN TECHNOLOGICAL UNI V HOUGHTON DEP T OF MFTALLU--ETC IG 11/6 ANNUAL TECHNICAL REPORT TO THE OFFICE OF NAVAL RESEARCH(U) NOV 81 D...A KOSS N00014-76-C-0037 UNCLASSIFIED NLmhEIIIIIIEIIII ElllllEllEllEE ANNUAL TECHNICAL REPORT TO THE OFFICE OF NAVAL RESEARCH CONTRACT No, N00014-76-C... the Office of Naval Research through Contract No. N00014-76-C-0037, NR 031-756. 22 References 1. K. Okazaki, M. Kagawa, and H. Conrad, Acta. Met. 27

24 CFR 983.261 - When occupancy may exceed 25 percent cap on the number of PBV units in each building.

Code of Federal Regulations, 2010 CFR

2010-04-01

... percent cap on the number of PBV units in each building. 983.261 Section 983.261 Housing and Urban...) PROGRAM Occupancy § 983.261 When occupancy may exceed 25 percent cap on the number of PBV units in each... contract for contract units in excess of the 25 percent cap pursuant to § 983.56(a). (b) In referring...

Shifts in the relationship between motor unit recruitment thresholds versus derecruitment thresholds during fatigue.

PubMed

Stock, Matt S; Mota, Jacob A

2017-12-01

Muscle fatigue is associated with diminished twitch force amplitude. We examined changes in the motor unit recruitment versus derecruitment threshold relationship during fatigue. Nine men (mean age = 26 years) performed repeated isometric contractions at 50% maximal voluntary contraction (MVC) knee extensor force until exhaustion. Surface electromyographic signals were detected from the vastus lateralis, and were decomposed into their constituent motor unit action potential trains. Motor unit recruitment and derecruitment thresholds and firing rates at recruitment and derecruitment were evaluated at the beginning, middle, and end of the protocol. On average, 15 motor units were studied per contraction. For the initial contraction, three subjects showed greater recruitment thresholds than derecruitment thresholds for all motor units. Five subjects showed greater recruitment thresholds than derecruitment thresholds for only low-threshold motor units at the beginning, with a mean cross-over of 31.6% MVC. As the muscle fatigued, many motor units were derecruited at progressively higher forces. In turn, decreased slopes and increased y-intercepts were observed. These shifts were complemented by increased firing rates at derecruitment relative to recruitment. As the vastus lateralis fatigued, the central nervous system's compensatory adjustments resulted in a shift of the regression line of the recruitment versus derecruitment threshold relationship. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

41 CFR 109-42.1102-8 - United States Munitions List items which require demilitarization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false United States Munitions List items which require demilitarization. 109-42.1102-8 Section 109-42.1102-8 Public Contracts and... Property § 109-42.1102-8 United States Munitions List items which require demilitarization. Heads of field...

41 CFR 109-42.1102-8 - United States Munitions List items which require demilitarization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false United States Munitions List items which require demilitarization. 109-42.1102-8 Section 109-42.1102-8 Public Contracts and... Property § 109-42.1102-8 United States Munitions List items which require demilitarization. Heads of field...

41 CFR 109-42.1102-8 - United States Munitions List items which require demilitarization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false United States Munitions List items which require demilitarization. 109-42.1102-8 Section 109-42.1102-8 Public Contracts and... Property § 109-42.1102-8 United States Munitions List items which require demilitarization. Heads of field...

Agreement between the State of New York and United University Professions--1988-1991.

ERIC Educational Resources Information Center

New York State Executive Office, Albany.

The collective bargaining agreement between the State of New York and United University Professions, an affiliate of the American Federation of Teachers, for the period July 1, 1988 to June 30, 1991 is presented. The contract's 50 articles cover the following: recognition, unchallenged representation, exclusive negotiations, definitions, policies,…

7 CFR 1403.8 - Withholding.

Code of Federal Regulations, 2013 CFR

2013-01-01

... payable to a debtor by CCC to ensure that the interests of CCC and the United States will be protected as provided in this section. (b) A payment may be withheld to protect the interests of CCC or the United States only if CCC determines that: (1) There has been a serious breach of contract or violation of...

7 CFR 1403.8 - Withholding.

Code of Federal Regulations, 2011 CFR

2011-01-01

... payable to a debtor by CCC to ensure that the interests of CCC and the United States will be protected as provided in this section. (b) A payment may be withheld to protect the interests of CCC or the United States only if CCC determines that: (1) There has been a serious breach of contract or violation of...

Development of Powder Processing Models and Techniques for Meso-scale Devices: Perspirable Skin

DTIC Science & Technology

2008-03-31

of Powder Processing Models and Techniques for Meso-scale Devices: Perspirable Skin Contract Number ...Skin 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9550-05-1-0202 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Patrick Kwon, Michigan State University 5d...PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Patrick Kwon Department of

48 CFR 3036.104-90 - Authority for one-step turn-key design-build contracting for the United States Coast Guard (USCG).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Authority for one-step... General 3036.104-90 Authority for one-step turn-key design-build contracting for the United States Coast Guard (USCG). The Head of the Contracting Activity (HCA) of the U.S. Coast Guard may use one-step turn...

With Interest It Comes To...Unconscionable Clauses in Sales Contracts. A Student's Lesson Plan [and] A Teacher's Lesson Plan [and] A Lawyer's Lesson Plan.

ERIC Educational Resources Information Center

Howard, Estelle; And Others

One of a series of secondary level teaching units presenting case studies with pro and con analysis of particular legal problems, the document presents a student's lesson plan, a teacher's lesson plan, and a lawyer's lesson plan on unconscionable clauses in sales contracts. The unit acquaints students with the operation of sales contracts and…

Energy Lessons by Contract.

ERIC Educational Resources Information Center

Wagganer, John W.

1981-01-01

An elementary activity based energy education unit which utilizes student contracts is described. Examples of the preparation involved, student involvement entailed, and examples of contracts and grading criteria are included. (DS)

48 CFR 237.7100 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Laundry and Dry Cleaning Services 237.7100 Scope. This subpart— (a) Applies to contracts for laundry and dry cleaning services within the United...

48 CFR 35.017-1 - Sponsoring agreements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Sponsoring agreements. 35... CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.017-1 Sponsoring agreements. (a) In order... mission, and ensure a periodic reevaluation of the FFRDC, a written agreement of sponsorship between the...

48 CFR 35.017-1 - Sponsoring agreements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Sponsoring agreements. 35... CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.017-1 Sponsoring agreements. (a) In order... mission, and ensure a periodic reevaluation of the FFRDC, a written agreement of sponsorship between the...

48 CFR 35.017-1 - Sponsoring agreements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Sponsoring agreements. 35... CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.017-1 Sponsoring agreements. (a) In order... mission, and ensure a periodic reevaluation of the FFRDC, a written agreement of sponsorship between the...

Transformations of Heavy Metals and Plant Nutrients in Dredged Sediments as Affected by Oxidation Reduction Potential and pH. Volume 2. Materials and Methods/Results and Discussion

DTIC Science & Technology

1977-05-01

D )EGED IATWRAL WI0, 00 EEACHPRGAFT4- CONTRACT REPORT D -77-4 TRANSFORMATIONS OF HEAVY METALS AND PLANT NUTRIENTS IN DREDGED SEDIMENTS AS AFFECTED BY...Engineers, U. S. Army C=) Washington, D . C. 20314 Q-2 Under Contract No. DACW39-74-C-0076 CM-1 (DMRP Work Unit No. IC05) Monitored by Environmental...Sa70mB COMPLETING FOM T -IMPORT PUNIeRf oTACSINN ESCTLGNME Contract Report D -77-4GOTACSINN C NTSAAOGUMR RAAN SFORATIONS OFPEAV71ETALS AND

Memories of early work on muscle contraction and regulation in the 1950's and 1960's

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huxley, Hugh E.

2008-04-25

Professor Ebashi's epic work on the biochemistry of the regulation of muscle contraction began in the early 1950's, during the same period that work on the molecular basis of force production in muscle was also beginning. The latter work started in two MRC Research Units in the UK, and was continued jointly by the two workers from those Units who had, independently, gone to MIT to learn the new techniques of electron microscopy and to apply them to muscle. In a somewhat similar fashion, Professor Ebashi also spent one or two years in the USA, continuing his work on themore » role of calcium in muscle regulation in Lippman's laboratory, before returning to Japan to achieve the great breakthroughs in this work during the 1960's. Hanson and Huxley, after putting forward the overlapping actin and myosin filament arrays model for the striated muscle sarcomere, and subsequently the sliding filament model of muscle contraction (simultaneously with A.F Huxley and R. Niedergerke), returned to the UK to pursue detailed structural studies in separate Research Units, in a mixture of consultation, collaboration, and competition, during the later 1950's and throughout the 1960's. However, the path to enlightenment described here in some detail was somewhat more tortuous than the standard literature perhaps reveals. Nevertheless, by the time of the Cold Spring Harbor Symposium on Muscle Contraction in 1972, the two lines of enquiry on regulation itself, and on the tilting cross-bridge model of force production, had arrived at a good deal of common ground, and indeed the identification of troponin and its periodic distribution along the actin filaments had helped resolve a long-standing puzzle in the interpretation of the low angle X-ray diagram. Since then, an enormous amount of remarkable new work has been necessary to establish troponin regulation and the tilting cross-bridge mechanism in molecular detail, but the work in the 1950's and 1960's has provided a firm and accurate basis for our current understanding.« less

Motor unit recruitment strategies and muscle properties determine the influence of synaptic noise on force steadiness

PubMed Central

Dideriksen, Jakob L.; Negro, Francesco; Enoka, Roger M.

2012-01-01

Motoneurons receive synaptic inputs from tens of thousands of connections that cause membrane potential to fluctuate continuously (synaptic noise), which introduces variability in discharge times of action potentials. We hypothesized that the influence of synaptic noise on force steadiness during voluntary contractions is limited to low muscle forces. The hypothesis was examined with an analytical description of transduction of motor unit spike trains into muscle force, a computational model of motor unit recruitment and rate coding, and experimental analysis of interspike interval variability during steady contractions with the abductor digiti minimi muscle. Simulations varied contraction force, level of synaptic noise, size of motor unit population, recruitment range, twitch contraction times, and level of motor unit short-term synchronization. Consistent with the analytical derivations, simulations and experimental data showed that force variability at target forces above a threshold was primarily due to low-frequency oscillations in neural drive, whereas the influence of synaptic noise was almost completely attenuated by two low-pass filters, one related to convolution of motoneuron spike trains with motor unit twitches (temporal summation) and the other attributable to summation of single motor unit forces (spatial summation). The threshold force above which synaptic noise ceased to influence force steadiness depended on recruitment range, size of motor unit population, and muscle contractile properties. This threshold was low (<10% of maximal force) for typical values of these parameters. Results indicate that motor unit recruitment and muscle properties of a typical muscle are tuned to limit the influence of synaptic noise on force steadiness to low forces and that the inability to produce a constant force during stronger contractions is mainly attributable to the common low-frequency oscillations in motoneuron discharge rates. PMID:22423000

48 CFR 2035.70 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... insert the following clause in all solicitations and contracts for research and development by private contractors and universities and for other technical services, as appropriate: (1) Section 2052.235-70...

48 CFR 2035.70 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... insert the following clause in all solicitations and contracts for research and development by private contractors and universities and for other technical services, as appropriate: (1) Section 2052.235-70...

48 CFR 2035.70 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... insert the following clause in all solicitations and contracts for research and development by private contractors and universities and for other technical services, as appropriate: (1) Section 2052.235-70...

48 CFR 2035.70 - Contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... insert the following clause in all solicitations and contracts for research and development by private contractors and universities and for other technical services, as appropriate: (1) Section 2052.235-70...

Triphasic behavioral response of motor units to submaximal fatiguing exercise.

PubMed

Dorfman, L J; Howard, J E; McGill, K C

1990-07-01

We have measured the firing rate and amplitude of 4551 motor unit action potentials (MUAPs) recorded with concentric needle electrodes from the brachial biceps muscles of 10 healthy young adults before, during, and after 45 minutes of intermittent isometric exercise at 20% of maximum voluntary contraction (MVC), using an automatic method for decomposition of electromyographic activity (ADEMG). During and after exercise, MUAPs derived from contractions of 30% MVC showed progressive increase in mean firing rate (P less than or equal to .01) and amplitude (P less than or equal to .05). The firing rate increase preceded the rise in mean amplitude, and was evident prior to the development of fatigue, defined as reduction of MVC. Analysis of individual potentials revealed that the increase in firing rate and in amplitude reflected different MUAP subpopulations. A short-term (less than 1 minute) reduction in MUAP firing rates (P less than or equal to .05) was also observed at the onset of each test contraction. These findings suggest that motor units exhibit a triphasic behavioral response to prolonged submaximal exercise: (1) short-term decline and stabilization of onset firing rates, followed by (2) gradual and progressive increase in firing rates and firing variability, and then by (3) recruitment of additional (larger) motor units. The (2) and (3) components presumably compensate for loss of force-generating capacity in the exercising muscle, and give rise jointly to the well-known increase in total surface EMG which accompanies muscle fatigue.

TEMTADS Adjunct Sensor Systems Hand-held EMI Sensor for Cued UXO Discrimination (ESTCP MR-200807) and Man-Portable EMI Array for UXO Detection and Discrimination (ESTCP MR-200909) Cost and Performance Report

DTIC Science & Technology

2012-06-27

notes and team orienteering functions. Data collection with the MP system at the former Camp Beale, CA is shown in Figure 5- 2 (right). 5.3.3...Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/ 6110 --12-9424 TEMTADS Adjunct Sensor Systems Hand-held EMI Sensor for Cued UXO...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 2 . REPORT TYPE1. REPORT DATE (DD

Fiscal Law Course Deskbook (36th)

DTIC Science & Technology

1993-05-01

CONTRACT LAW DIVISION THE JUDGE ADVOCATE GENERAL’S SCHOOL UNITED STATES ARMY CHARLOTTESVILLE, VIRGINIA JA 506...MAY 93 93-13173 CONTRIBUTORS I LTC John T. Jones, Jr. Chief, Contract Law Division LTC Harry L. Dorsey Senior Instructor, Contract Law Division MAJ...Michael A. Killham Instructor, Contract Law Division MAJ Bobby D. Melvin Instructor, Contract Law Division MAJ Michael K. Cameron Instructor, Contract

23 CFR 635.115 - Agreement estimate.

Code of Federal Regulations, 2010 CFR

2010-04-01

... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.115 Agreement estimate. (a) Following the award of contract, an agreement estimate based on the contract unit prices and estimated quantities shall be...

Defense Small Business Innovation Research Program (SBIR). Volume 3. Air Force Abstracts of Phase 1 Awards from FY 1988 SBIR Solicitation

DTIC Science & Technology

1989-05-01

THE TARGET DOPPLER FREQUENCIES. ADAPTIVE SENSORS INC 216 PICO BLVD - STE 8 SANTA MONICA, CA 90405 CONTRACT NUMBER: JOHN S BAILEY TITLE: SPATIALLY...APPLIED RESEARCH ASSOCS INC 4300 SAN MATEO BLVD NE - STE A220 ALBUQUERQUE, NM 87110 CONTRACT NUMBER: FRANK A MAESTAS TITLE: PARAMETRIC ANALYSIS OF EXPLOSIVE...VERIFIED THROUGH SUBSCALE FABRICATION AND TEST. AV DYNAMICS INC 825 MYRTLE AVE MONROVIA, CA 91016 CONTRACT NUMBER: DR P B S LISSAMAN TITLE: LIGHT WEIGHT

14. DREDGING MAP. United Engineering Company Ltd., Alameda Shipyard. Ship ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. DREDGING MAP. United Engineering Company Ltd., Alameda Shipyard. Ship repair facilities dredging map. No architect noted. Drawn by "J.H." (John Hudspeth?). Sheet 1. Plan no. 10,529. Scale one inch to 50 feet. September 22, 1943. U.S. Navy, Bureau of Yards & Docks, Contract no. bs 76. Approved for construction October 18, 1943. blueprint - United Engineering Company Shipyard, 2900 Main Street, Alameda, Alameda County, CA

Prediction of fire spread following nuclear explosions

Treesearch

Craig C. Chandler; Theodore G. Storey; Charles D. Tangren

1963-01-01

Mass fires are likely to follow a nuclear attack. Since it is important to the civil defense program to be able to predict rate, duration, and extent of spread of such fires, the Office of Civil Defense, U.S. Department of Defense, issued a joint contract to the Forest Service and to United Research Services, Inc., to study this field. We surveyed the literature,...

Training Lessons Learned from Peak Performance Episodes

DTIC Science & Technology

1986-06-01

PEAK PERFORMAN4CE Fina Report- EPSOESOctober 1984-December 1985 % 6. PERFORMING ORG. REPORT NUMBER * 7. AUTHOR(@) 6. CONTRACT OR GRANT NUMBER(s) James...L. Fobes - 9. PERFORMING ORGANIZATION NAME AND) ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASK U.S. Army Research Institute Field UnitAEA OKUINMER...peak performance indicates that three cogni- . tive components enable these episodes: psychological readiness (activating . optimal arousal and emotion

The Slippery Slope of Air Force Downsizing: A Strategy Connection

DTIC Science & Technology

2013-02-14

as the reductions continue. As an example, commanders and their Airmen are responsible for being administration, personnel, finance, communciations ... computer efficient because the expertise in their units or base has been reduced, eliminated or consolidated. This impacts the time and resources...are the areas that require additional research. • Issue: Other functional issues (Logistics, Finance, Contracting, Communications/ computers , Nuclear

"Shoe-Horned and Side-Lined"? Challenges for Part-Time Learners in the New HE Landscape

ERIC Educational Resources Information Center

Butcher, John

2015-01-01

This research set out to investigate the part-time student experience of higher education across the United Kingdom, in the context of a well-publicised contraction in the sector, and increasing divergence between policies affecting part-time study in the four nations. In order to explore the part-time student experience in England, Scotland, and…

Financial and clinical risk in health care reform: a view from below.

PubMed

Smith, Pam; Mackintosh, Maureen; Ross, Fiona; Clayton, Julie; Price, Linnie; Christian, Sara; Byng, Richard; Allan, Helen

2012-04-01

This paper examines how the interaction between financial and clinical risk at two critical phases of health care reform in England has been experienced by frontline staff caring for vulnerable patients with long term conditions. The paper draws on contracting theory and two interdisciplinary and in-depth qualitative research studies undertaken in 1995 and 2007. Methods common to both studies included documentary analysis and interviews with managers and front line professionals. The 1995 study employed action-based research and included observation of community care; the 2007 study used realistic evaluation and included engagement with service user groups. In both reform processes, financial risk was increasingly devolved to frontline practitioners and smaller organizational units such as GP commissioning groups, with payment by unit of activity, aimed at changing professionals' behaviour. This financing increased perceived clinical risk and fragmented the delivery of health and social care services requiring staff efforts to improve collaboration and integration, and created some perverse incentives and staff demoralisation. Health services reform should only shift financial risk to frontline professionals to the extent that it can be efficiently borne. Where team work is required, contracts should reward collaborative multi-professional activity.

48 CFR 335.071 - Special determinations and findings affecting research and development contracting.

Code of Federal Regulations, 2010 CFR

2010-10-01

... findings affecting research and development contracting. 335.071 Section 335.071 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 335.071 Special determinations and findings affecting research and development contracting. OPDIV...

Translations on Telecommunications Policy, Research and Development, Number 44.

DTIC Science & Technology

1978-07-07

Research Service 1000 North Glebe Road Arlington, Virginia 22201 10. Project/Task/ Work Unit No. 11. Contract/Grant No. 12. Sponsoring Organization...station in Khisarya to make the telephone operators polite to the citizens? A standard is one thing, that is to work with a living person and he must...ably in certain instances we hear this, we understand it at the moment we are in this room, and after leaving it we continue to work as we did before

Adjoint-Free Variational Data Assimilation into a Regional Wave Model

DTIC Science & Technology

2015-07-01

Wave Model 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER...developed by Oceanweather, Inc. using the methodology of Cardone et al. (1995, 1996). The winds were taken for the period 11–20 September 2011 and...International Arctic Research Center, NSF Grants 1107925 and 1203740. It was also supported by theOffice of Naval Research (Program Element 0602435N, pro

Recruitment of single human low-threshold motor units with increasing loads at different muscle lengths.

PubMed

McNulty, P A; Cresswell, A G

2004-06-01

We investigated the recruitment behaviour of low threshold motor units in flexor digitorum superficialis by altering two biomechanical constraints: the load against which the muscle worked and the initial muscle length. The load was increased using isotonic (low load), loaded dynamic (intermediate load) and isometric (high load) contractions in two studies. The initial muscle position reflected resting muscle length in series A, and a longer length with digit III fully extended in series B. Intramuscular EMG was recorded from 48 single motor units in 10 experiments on five healthy subjects, 21 units in series A and 27 in series B, while subjects performed ramp up, hold and ramp down contractions. Increasing the load on the muscle decreased the force, displacement and firing rate of single motor units at recruitment at shorter muscle lengths (P<0.001, dependent t-test). At longer muscle lengths this recruitment pattern was observed between loaded dynamic and isotonic contractions, but not between isometric and loaded dynamic contractions. Thus, the recruitment properties of single motor units in human flexor digitorum superficialis are sensitive to changes in both imposed external loads and the initial length of the muscle.

Principles of Training in Marine Corps Task Analysis. Training Manual 1

DTIC Science & Technology

1975-12-01

Training Research Programs Psychological Sciences Division Office of Naval Research Contract No. N00014-74-A-0436-0001 NR 151-370 Approved for...and Training Research Programs Psychological Sciences Division Office of Naval Research Contract No. N00014-74-A-0436-0001 NR 151-370 Approved... psychological reward; the trainee loses the connection between performance and the pat on the back that is its consequence. DIMENSIONS OF THE TRAINING

Guidelines for Research Planning and Design in Task Analysis

DTIC Science & Technology

1975-09-01

Personnel and Training Research Programs Psychological Sciences Division Office of Naval Research Contract No. N00014-74-A-0436-0001 NR 151-370...Programs Psychological Sciences Division Office of Naval Research Contract No. N00014-74-A-0436-0001 NR 151-370 Approved for public release...for ways in which the hypothesis can be tested . There are 11 several ways to do this and they are often used jointly. 1* Review of the Literature

A Summary of the FHWA Contract Administration Techniques for Quality Enhancement Study Tour (CATQEST)

DOT National Transportation Integrated Search

1994-06-01

There is a widespread impression in the United States that roads and highway structures in Europe are generally superior to comparable facilities in the United States. The joint industry and government project, the Contract Administration Techniques ...

Production Assistance for Cellular Therapies (PACT): four-year experience from the United States National Heart, Lung, and Blood Institute (NHLBI) contract research program in cell and tissue therapies.

PubMed

Reed, William; Noga, Stephen J; Gee, Adrian P; Rooney, Cliona M; Wagner, John E; McCullough, Jeffrey; McKenna, David H; Whiteside, Theresa L; Donnenberg, Albert D; Baker, Acacia K; Lindblad, Robert W; Wagner, Elizabeth L; Mondoro, Traci Heath

2009-04-01

In 2002, the US National Heart, Lung, and Blood Institute (NHLBI) conducted a workshop to determine needs of the cell therapy community. A consensus emerged that improved access to cGMP facilities, regulatory assistance, and training would foster the advancement of cellular therapy. A 2003 NHLBI request for proposals resulted in four contracts being awarded to three cell-manufacturing facilities (Baylor College of Medicine, University of Minnesota, and University of Pittsburgh) and one administrative center (The EMMES Corporation). As a result, Production Assistance for Cellular Therapies (PACT) was formed. As of October 1, 2008, PACT has received 65 preliminary applications of which 45 have been approved for product manufacture. A variety of cell therapies are represented including T-regulatory cells, natural killer cells, adipose-derived stem cells, cardiac progenitor cells for cardiac disease, hematopoietic progenitor cells (HPCs) for central nervous system applications, cytotoxic T lymphocytes, and dendritic cells. A total of 169 products have been administered under 12 applications and 2 reagents were manufactured and delivered. Fourteen peer-reviewed publications and 15 abstracts have resulted from the PACT project to date. A cell therapy textbook is nearly complete. PACT technical projects have addressed assay development, rapid endotoxin testing, shipping of cell products, and CD34+ HPC isolation from low-volume marrow. Educational Web seminars and on-site training through workshops have been conducted. PACT is an active and successful cell therapy manufacturing resource in the United States, addressing research and training while forging relationships among academia, industry, and participating institutions.

A Closer Look at the Junior Doctor Crisis in the United Kingdom's National Health Services: Is Emigration Justifiable?

PubMed

Teo, Wendy Zi Wei

2018-07-01

This article attempts to tackle the ethically and morally troubling issue of emigration of physicians from the United Kingdom, and whether it can be justified. Unlike most research that has already been undertaken in this field, which looks at migration from developing countries to developed countries, this article takes an in-depth look at the migration of physicians between developed countries, in particular from the United Kingdom (UK) to other developed countries such as Canada, Australia, New Zealand, and the United States (US). This examination was written in response to a current and critical crisis in the National Health Service (NHS), where impending contract changes may bring about a potential exodus of junior doctors.

32 CFR 744.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Department of Defense (Continued) DEPARTMENT OF THE NAVY PROCUREMENT, PROPERTY, PATENTS, AND CONTRACTS... RELEASE TO FOREIGN GOVERNMENTS § 744.1 Purpose. This part implements part 264 of this title and the Technical Property Interchange Agreements between the United States and foreign governments which agreements...

47 CFR 1.1917 - Referrals to the Department of Justice and transfer of delinquent debt to the Secretary of Treasury.

Code of Federal Regulations, 2013 CFR

2013-10-01

... United States Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1.1917... given debt. Under section 3711(g), Treasury will use all appropriate debt collection tools to collect...

47 CFR 1.1917 - Referrals to the Department of Justice and transfer of delinquent debt to the Secretary of Treasury.

Code of Federal Regulations, 2012 CFR

2012-10-01

... United States Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1.1917... given debt. Under section 3711(g), Treasury will use all appropriate debt collection tools to collect...

47 CFR 1.1917 - Referrals to the Department of Justice and transfer of delinquent debt to the Secretary of Treasury.

Code of Federal Regulations, 2014 CFR

2014-10-01

... United States Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1.1917... given debt. Under section 3711(g), Treasury will use all appropriate debt collection tools to collect...

Female pheromones modulate flight muscle activation patterns during preflight warm-up.

PubMed

Crespo, José G; Vickers, Neil J; Goller, Franz

2013-08-01

At low ambient temperature Helicoverpa zea male moths engage in warm-up behavior prior to taking flight in response to an attractive female pheromone blend. Male H. zea warm up at a faster rate when sensing the attractive pheromone blend compared with unattractive blends or blank controls (Crespo et al. 2012), but the mechanisms involved in this olfactory modulation of the heating rate during preflight warm-up are unknown. Here, we test three possible mechanisms for increasing heat production: 1) increased rate of muscle contraction; 2) reduction in mechanical movement by increased overlap in activation of the antagonistic flight muscles; and 3) increased activation of motor units. To test which mechanisms play a role, we simultaneously recorded electrical activation patterns of the main flight muscles (dorsolongitudinal and dorsoventral muscles), wing movement, and thoracic temperature in moths exposed to both the attractive pheromone blend and a blank control. Results indicate that the main mechanism responsible for the observed increase in thoracic heating rate with pheromone stimulation is the differential activation of motor units during each muscle contraction cycle in both antagonistic flight muscles. This additional activation lengthens the contracted state within each cycle and thus accounts for the greater heat production. Interestingly, the rate of activation (frequency of contraction cycles) of motor units, which is temperature dependent, did not vary between treatments. This result suggests that the activation rate is determined by a temperature-dependent oscillator, which is not affected by the olfactory stimulus, but activation of motor units is modulated during each cycle.

Female pheromones modulate flight muscle activation patterns during preflight warm-up

PubMed Central

Vickers, Neil J.; Goller, Franz

2013-01-01

At low ambient temperature Helicoverpa zea male moths engage in warm-up behavior prior to taking flight in response to an attractive female pheromone blend. Male H. zea warm up at a faster rate when sensing the attractive pheromone blend compared with unattractive blends or blank controls (Crespo et al. 2012), but the mechanisms involved in this olfactory modulation of the heating rate during preflight warm-up are unknown. Here, we test three possible mechanisms for increasing heat production: 1) increased rate of muscle contraction; 2) reduction in mechanical movement by increased overlap in activation of the antagonistic flight muscles; and 3) increased activation of motor units. To test which mechanisms play a role, we simultaneously recorded electrical activation patterns of the main flight muscles (dorsolongitudinal and dorsoventral muscles), wing movement, and thoracic temperature in moths exposed to both the attractive pheromone blend and a blank control. Results indicate that the main mechanism responsible for the observed increase in thoracic heating rate with pheromone stimulation is the differential activation of motor units during each muscle contraction cycle in both antagonistic flight muscles. This additional activation lengthens the contracted state within each cycle and thus accounts for the greater heat production. Interestingly, the rate of activation (frequency of contraction cycles) of motor units, which is temperature dependent, did not vary between treatments. This result suggests that the activation rate is determined by a temperature-dependent oscillator, which is not affected by the olfactory stimulus, but activation of motor units is modulated during each cycle. PMID:23699056

Time to Maximal Voluntary Isometric Contraction (MVC) for Five Different Muscle Groups in College Adults.

ERIC Educational Resources Information Center

Morris, A. F.; And Others

1983-01-01

College men and women were studied to ascertain the force-time components of a rapid voluntary muscle contraction for five muscle groups. Researchers found that the time required for full contraction differs: (1) in men and women; and (2) among the five muscle groups. (Authors/PP)

Contingency Contracting and Operant Behavior Change: An Exercise in Applied Behavior Analysis.

ERIC Educational Resources Information Center

Mann, Ronald A.

Until recently, the use of contingency contracting has been largely an issue of theory and discussion with little experimental research evidence gathered to support efficacy. Two major reasons for this problem are suggested and discussed: (1) the concept of contingency contracting has not been adequately defined nor its minimal requirements…

Development of Precoat Filtration Technology for Reverse Osmosis Units

DTIC Science & Technology

1981-11-20

CONTRACT DAAK 70-79-C-0046 0 FINAL REPORT 0 DEVELOPMENT OF PRECOAT FILTRATION TECHNOLOGY FOR REVERSE OSMOSIS UNITS Submitted by: ,i JOHNS - MANVILLE SALES...NTU (Hach). The one square foot vertical leaf filter was set up at the Johns - Manville R&D Center as shown in Figure 1. A 300 gallon feed tank was

12 CFR Appendix A to Subpart A of... - Minimum Capital Components for Interest Rate and Foreign Exchange Rate Contracts

Code of Federal Regulations, 2010 CFR

2010-01-01

... sheet interest rate and foreign exchange rate contracts: a. Interest Rate Contracts i. Single currency... Contracts i. Cross-currency interest rate swaps. ii. Forward foreign exchange rate contracts. iii. Currency... exposure is zero. Mark-to-market values are measured in United States dollars, regardless of the currency...

47 CFR 1.1918 - Use of consumer reporting agencies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Use of consumer reporting agencies. 1.1918... Collection of Claims Owed the United States Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1.1918 Use of consumer reporting agencies. (a) The term individual means a natural person, and...

47 CFR 1.1918 - Use of consumer reporting agencies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false Use of consumer reporting agencies. 1.1918... Collection of Claims Owed the United States Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1.1918 Use of consumer reporting agencies. (a) The term individual means a natural person, and...

48 CFR 242.1402 - Volume movements within the contiguous United States.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Volume movements within the contiguous United States. 242.1402 Section 242.1402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT...

Contractual Duration and Investment Incentives: Evidence from Large Scale Production Units in China

NASA Astrophysics Data System (ADS)

Li, Fang; Feng, Shuyi; D'Haese, Marijke; Lu, Hualiang; Qu, Futian

2017-04-01

Large Scale Production Units have become important forces in the supply of agricultural commodities and agricultural modernization in China. Contractual duration in farmland transfer to Large Scale Production Units can be considered to reflect land tenure security. Theoretically, long-term tenancy contracts can encourage Large Scale Production Units to increase long-term investments by ensuring land rights stability or favoring access to credit. Using a unique Large Scale Production Units- and plot-level field survey dataset from Jiangsu and Jiangxi Province, this study aims to examine the effect of contractual duration on Large Scale Production Units' soil conservation behaviours. IV method is applied to take into account the endogeneity of contractual duration and unobserved household heterogeneity. Results indicate that farmland transfer contract duration significantly and positively affects land-improving investments. Policies aimed at improving transaction platforms and intermediary organizations in farmland transfer to facilitate Large Scale Production Units to access farmland with long-term tenancy contracts may therefore play an important role in improving soil quality and land productivity.

I Am So Tired… How Fatigue May Exacerbate Stress Reactions to Psychological Contract Breach

PubMed Central

Achnak, Safâa; Griep, Yannick; Vantilborgh, Tim

2018-01-01

Previous research showed that perceptions of psychological contract (PC) breach have undesirable individual and organizational consequences. Surprisingly, the PC literature has paid little to no attention to the relationship between PC breach perceptions and stress. A better understanding of how PC breach may elicit stress seems crucial, given that stress plays a key role in employees' physical and mental well-being. Based on Conservation of Resources Theory, we suggest that PC breach perceptions represent a perceived loss of valued resources, subsequently leading employees to experience higher stress levels resulting from emerging negative emotions. Moreover, we suggest that this mediated relationship is moderated by initial levels of fatigue, due to fatigue lowering the personal resources necessary to cope with breach events. To tests our hypotheses, we analyzed the multilevel data we obtained from two experience sampling designs (Study 1: 51 Belgian employees; Study 2: 53 US employees). Note that the unit of analysis is “observations” rather than “respondents,” resulting in an effective sample size of 730 (Study 1) and 374 (Study 2) observations. In both studies, we found evidence for the mediating role of negative emotions in the PC breach—stress relationship. In the second study, we also found evidence for the moderating role of fatigue in the mediated PC breach—stress relationship. Implications for research and practice are discussed. PMID:29559935

I Am So Tired… How Fatigue May Exacerbate Stress Reactions to Psychological Contract Breach.

PubMed

Achnak, Safâa; Griep, Yannick; Vantilborgh, Tim

2018-01-01

Previous research showed that perceptions of psychological contract (PC) breach have undesirable individual and organizational consequences. Surprisingly, the PC literature has paid little to no attention to the relationship between PC breach perceptions and stress. A better understanding of how PC breach may elicit stress seems crucial, given that stress plays a key role in employees' physical and mental well-being. Based on Conservation of Resources Theory, we suggest that PC breach perceptions represent a perceived loss of valued resources, subsequently leading employees to experience higher stress levels resulting from emerging negative emotions. Moreover, we suggest that this mediated relationship is moderated by initial levels of fatigue, due to fatigue lowering the personal resources necessary to cope with breach events. To tests our hypotheses, we analyzed the multilevel data we obtained from two experience sampling designs (Study 1: 51 Belgian employees; Study 2: 53 US employees). Note that the unit of analysis is "observations" rather than "respondents," resulting in an effective sample size of 730 (Study 1) and 374 (Study 2) observations. In both studies, we found evidence for the mediating role of negative emotions in the PC breach-stress relationship. In the second study, we also found evidence for the moderating role of fatigue in the mediated PC breach-stress relationship. Implications for research and practice are discussed.

Advanced Stirling Convertor (ASC) Development for NASA RPS

NASA Technical Reports Server (NTRS)

Wong, Wayne A.; Wilson, Scott; Collins, Josh

2014-01-01

Sunpower's Advanced Stirling Convertor (ASC) initiated development under contract to the NASA Glenn Research Center (GRC) and after a series of successful demonstrations, the ASC began transitioning from a technology development project to flight development project. The ASC has very high power conversion efficiency making it attractive for future Radioisotope Power Systems (RPS) in order to make best use of the low plutonium-238 fuel inventory in the U.S. In recent years, the ASC became part of the NASA-Department of Energy Advanced Stirling Radioisotope Generator (ASRG) Integrated Project. Sunpower held two parallel contracts to produce ASC convertors, one with the Department of Energy/Lockheed Martin to produce the ASC-F flight convertors, and one with NASA GRC for the production of ASC-E3 engineering units, the initial units of which served as production pathfinders. The integrated ASC technical team successfully overcame various technical challenges that led to the completion and delivery of the first two pairs of flight-like ASC-E3 by 2013. However, in late Fall 2013, the DOE initiated termination of the Lockheed Martin ASRG flight development contract driven primarily by budget constraints. NASA continues to recognize the importance of high efficiency ASC power conversion for RPS and continues investment in the technology including the continuation of ASC-E3 production at Sunpower and the assembly of the ASRG Engineering Unit #2. This paper provides a summary of ASC technical accomplishments, overview of tests at GRC, plans for continued ASC production at Sunpower, and status of Stirling technology development.

48 CFR 750.7110-5 - Contract files.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

48 CFR 750.7110-5 - Contract files.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

48 CFR 750.7110-5 - Contract files.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

48 CFR 750.7110-5 - Contract files.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

Muscular contraction stimulates posterior hypothalamic neurons.

PubMed

Waldrop, T G; Stremel, R W

1989-02-01

Recent studies have suggested that the subthalamic locomotor region (STLR) of the posterior hypothalamus is involved in modulating cardiorespiratory responses to feedback from contracting muscles. The purpose of this study was to determine whether neurons in this hypothalamic region alter their discharge frequency during contraction of hindlimb muscles. Stainless steel electrodes were used to record single-unit activity of STLR neurons during static and rhythmic contractions of hindlimb muscles in anesthetized cats. Recordings were also made from neurons in areas outside but surrounding the subthalamic locomotor region. Contraction of the triceps surae muscles was induced by stimulation of the peripheral cut ends of the L7 and S1 ventral roots. Both static and rhythmic contractions of the triceps surae evoked an increase in the discharge rate of the majority of the STLR cells studied. Two types of excitatory responses were observed: 1) abrupt increases in discharge frequency at the onset of muscular contraction and 2) a delayed more gradual increase in firing. Most of the cells that responded to muscular contraction could be activated by mechanical probing of the triceps surae muscles. However, the changes in discharge frequency were unrelated to changes in arterial pressure occurring during muscular contraction. Most of the neurons located outside the STLR were slightly inhibited by or did not respond to muscular contraction. Thus input from contracting muscles exerts predominantly an excitatory effect on neurons in the posterior hypothalamus. These results are consistent with other studies which have concluded that this hypothalamic site is involved in influencing the cardiorespiratory responses to muscular contraction.

48 CFR 1235.7000 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

... all solicitations and contracts for research and development. For further information, see DOT's Implementation Guidance for Executive Office of the President, Office of Science and Technology Policy, “Federal... OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING Research Misconduct 1235.7000 Contract clause...

Multilayer Pressure Vessel Materials Testing and Analysis. Phase 1

NASA Technical Reports Server (NTRS)

Cardinal, Joseph W.; Popelar, Carl F.; Page, Richard A.

2014-01-01

To provide NASA a comprehensive suite of materials strength, fracture toughness and crack growth rate test results for use in remaining life calculations for aging multilayer pressure vessels, Southwest Research Institute (R) (SwRI) was contracted in two phases to obtain relevant material property data from a representative vessel. This report describes Phase 1 of this effort which includes a preliminary material property assessment as well as a fractographic, fracture mechanics and fatigue crack growth analyses of an induced flaw in the outer shell of a representative multilayer vessel that was subjected to cyclic pressure test. SwRI performed this Phase 1 effort under contract to the Digital Wave Corporation in support of their contract to Jacobs ATOM for the NASA Ames Research Center.

Hazard Response Modeling Uncertainty (A Quantitative Method)

DTIC Science & Technology

1988-10-01

was conducted by the National Maritime Institute under contract to the United Kingdom Health and Safety Executive. Instantaneous releases of 2000...the National Maritime Institute under contract to the United Kingdom Health and Safety Executive with the sponsorship of numerous international...WORK UNIT ELEMENT NO. NO. NO. ACESSION NO. _____________________65502F I 00O ne I " 11. TITLE (incl& e Security Oauffication) Hazard Response

Joint Forces Command - United Assistance Fiscal Triad

DTIC Science & Technology

2016-05-17

Division G–8, the 922nd Contracting Battalion (CBN), and C Detachment, 101st Financial Management Support Unit (C/101st FMSU) all deployed from Fort...Campbell, Kentucky, to resource OUA. This “fiscal triad” of resource management , contingency contracting, and financial operations units funded...of De- fense (DOD) operations to come in under budget , under the anticipated time, and with less manpower than initially requested. Planning and

Weaknesses in Awarding Fees for the Broad Area Maritime Surveillance Contract

DTIC Science & Technology

2010-11-02

Table of Contents Introduction 1 Audit Objectives 1 Background on Broad Area Maritime Surveillance 1...24 Mangement Comments The Assistant Secretary of the Navy for Research, Development, and Acquisition 25... Introduction Audit Objectives This is the first in a series of reports on the contract supporting the Broad Area Maritime

Influence of curing mode with a LED unit on polymerization contraction kinetics and degree of conversion of dental resin-based materials.

PubMed

Mortier, Eric; Simon, Yorick; Dahoun, Abdelsellam; Gerdolle, David

2009-01-01

The purpose of this study was to evaluate the influence of photopolymerization mode with a light emitting diode (LED) lamp on the curing contraction kinetics and degree of conversion of 3 resin-based restorative materials. The curing contraction kinetics of Admira (ADM), Filtek P60 (P60), and Filtek Flow (FLO) were measured by the glass slide method. The materials were exposed to light from a 1,000 mW/cm-(2) power LED lamp (Elipar Freelight 2) in 3 modes: 2 continuous modes of 20 and 40 seconds (C20 and C40), and 1 exponential mode (E20; 5 seconds of exponential power increase followed by 15 seconds of maximum intensity). The degree of conversion (DC) was measured for each of the materials, and each of the modes by Fourier transformed infra-red spectrometry. P60 had the significantly lowest final contraction and FLO the highest among all light exposure modes. The C20 and C40 modes did not produce any difference in contraction or degree of conversion. The E20 mode led to a significant slowing of contraction speed combined with greater final contraction. Use of a LED lamp (1,000 mW/cm2) in continuous mode reduces the exposure time by half for identical curing shrinkage and degree of conversion.

Discharge properties of motor units during steady isometric contractions performed with the dorsiflexor muscles

PubMed Central

Klass, Malgorzata; Duchateau, Jacques; Enoka, Roger M.

2012-01-01

The purpose of this study was to record the discharge characteristics of tibialis anterior motor units over a range of target forces and to import these data, along with previously reported observations, into a computational model to compare experimental and simulated measures of torque variability during isometric contractions with the dorsiflexor muscles. The discharge characteristics of 44 motor units were quantified during brief isometric contractions at torques that ranged from recruitment threshold to an average of 22 ± 14.4% maximal voluntary contraction (MVC) torque above recruitment threshold. The minimal [range: 5.8–19.8 pulses per second (pps)] and peak (range: 8.6–37.5 pps) discharge rates of motor units were positively related to the recruitment threshold torque (R2 ≥ 0.266; P < 0.001). The coefficient of variation for interspike interval at recruitment was positively associated with recruitment threshold torque (R2 = 0.443; P < 0.001) and either decreased exponentially or remained constant as target torque increased above recruitment threshold torque. The variability in the simulated torque did not differ from the experimental values once the recruitment range was set to ∼85% MVC torque, and the association between motor twitch contraction times and peak twitch torque was defined as a weak linear association (R2 = 0.096; P < 0.001). These results indicate that the steadiness of isometric contractions performed with the dorsiflexor muscle depended more on the distributions of mechanical properties than discharge properties across the population of motor units in the tibialis anterior. PMID:22442023

Discharge properties of motor units during steady isometric contractions performed with the dorsiflexor muscles.

PubMed

Jesunathadas, Mark; Klass, Malgorzata; Duchateau, Jacques; Enoka, Roger M

2012-06-01

The purpose of this study was to record the discharge characteristics of tibialis anterior motor units over a range of target forces and to import these data, along with previously reported observations, into a computational model to compare experimental and simulated measures of torque variability during isometric contractions with the dorsiflexor muscles. The discharge characteristics of 44 motor units were quantified during brief isometric contractions at torques that ranged from recruitment threshold to an average of 22 ± 14.4% maximal voluntary contraction (MVC) torque above recruitment threshold. The minimal [range: 5.8-19.8 pulses per second (pps)] and peak (range: 8.6-37.5 pps) discharge rates of motor units were positively related to the recruitment threshold torque (R(2) ≥ 0.266; P < 0.001). The coefficient of variation for interspike interval at recruitment was positively associated with recruitment threshold torque (R(2) = 0.443; P < 0.001) and either decreased exponentially or remained constant as target torque increased above recruitment threshold torque. The variability in the simulated torque did not differ from the experimental values once the recruitment range was set to ∼85% MVC torque, and the association between motor twitch contraction times and peak twitch torque was defined as a weak linear association (R(2) = 0.096; P < 0.001). These results indicate that the steadiness of isometric contractions performed with the dorsiflexor muscle depended more on the distributions of mechanical properties than discharge properties across the population of motor units in the tibialis anterior.

48 CFR 25.302-4 - Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Policy. 25.302-4 Section... FOREIGN ACQUISITION Contracts Performed Outside the United States 25.302-4 Policy. (a) General. (1) The policy, responsibilities, procedures, accountability, training, equipping, and conduct of personnel...

Translational Research for Muscular Dystrophy

DTIC Science & Technology

2012-05-01

common in-frame deletions for which clinical information from human Becker muscular dystrophy patients (deletion of exons 44-45, 49-51, 48-53) is lacking... Dystrophy PRINCIPAL INVESTIGATOR: Gregory A. Cox, Ph.D. CONTRACTING ORGANIZATION: The Jackson Laboratory...REPORT TYPE Annual 3. DATES COVERED 1 MAR 2011 - 30 APR 2012 4. TITLE AND SUBTITLE Translational Research for Muscular Dystrophy 5a. CONTRACT

Testing to Characterize the Advanced Stirling Radioisotope Generator Engineering Unit

NASA Technical Reports Server (NTRS)

Lewandowski, Edward; Schreiber, Jeffrey

2010-01-01

The Advanced Stirling Radioisotope Generator (ASRG), a high efficiency generator, is being considered for space missions. Lockheed Martin designed and fabricated an engineering unit (EU), the ASRG EU, under contract to the Department of Energy. This unit is currently undergoing extended operation testing at the NASA Glenn Research Center to generate performance data and validate life and reliability predictions for the generator and the Stirling convertors. It has also undergone performance tests to characterize generator operation while varying control parameters and system inputs. This paper summarizes and explains test results in the context of designing operating strategies for the generator during a space mission and notes expected differences between the EU performance and future generators.

Testing of the Advanced Stirling Radioisotope Generator Engineering Unit at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Lewandowski, Edward J.

2013-01-01

The Advanced Stirling Radioisotope Generator (ASRG) is a high-efficiency generator being developed for potential use on a Discovery 12 space mission. Lockheed Martin designed and fabricated the ASRG Engineering Unit (EU) under contract to the Department of Energy. This unit was delivered to NASA Glenn Research Center in 2008 and has been undergoing extended operation testing to generate long-term performance data for an integrated system. It has also been used for tests to characterize generator operation while varying control parameters and system inputs, both when controlled with an alternating current (AC) bus and with a digital controller. The ASRG EU currently has over 27,000 hours of operation. This paper summarizes all of the tests that have been conducted on the ASRG EU over the past 3 years and provides an overview of the test results and what was learned.

Engine Validation of Noise and Emission Reduction Technology Phase I

NASA Technical Reports Server (NTRS)

Weir, Don (Editor)

2008-01-01

This final report has been prepared by Honeywell Aerospace, Phoenix, Arizona, a unit of Honeywell International, Inc., documenting work performed during the period December 2004 through August 2007 for the NASA Glenn Research Center, Cleveland, Ohio, under the Revolutionary Aero-Space Engine Research (RASER) Program, Contract No. NAS3-01136, Task Order 8, Engine Validation of Noise and Emission Reduction Technology Phase I. The NASA Task Manager was Dr. Joe Grady of the NASA Glenn Research Center. The NASA Contract Officer was Mr. Albert Spence of the NASA Glenn Research Center. This report is for a test program in which NASA funded engine validations of integrated technologies that reduce aircraft engine noise. These technologies address the reduction of engine fan and jet noise, and noise associated with propulsion/airframe integration. The results of these tests will be used by NASA to identify the engineering tradeoffs associated with the technologies that are needed to enable advanced engine systems to meet stringent goals for the reduction of noise. The objectives of this program are to (1) conduct system engineering and integration efforts to define the engine test-bed configuration; (2) develop selected noise reduction technologies to a technical maturity sufficient to enable engine testing and validation of those technologies in the FY06-07 time frame; (3) conduct engine tests designed to gain insight into the sources, mechanisms and characteristics of noise in the engines; and (4) establish baseline engine noise measurements for subsequent use in the evaluation of noise reduction.

A Dictionary of Acquisition and Contracting Terms

DTIC Science & Technology

1990-12-01

consolidated national effort had been undertaken in this regard. Various individuals, commands and schools have attempted to assemble elements of definitions...however, the lack of a consolidated effort has caused a disparity in the definitions of terms. Previous graduate theses have researched definitions and...Supply Corps (SC), United States Navy (USN) initiated the consolidation of baseline consensus definitions in 1988. In 1989, Captain (CPT) John Cannaday

Character Development of U.S. Army Leaders: A Laissez Faire Approach

DTIC Science & Technology

2013-03-01

Character Development of U.S. Army Leaders: A Laissez Faire Approach by Colonel Brian M. Michelson United States Army...Army Leaders: A Laissez Faire Approach 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Colonel Brian M...STRATEGY RESEARCH PROJECT Character Development of U.S. Army Leaders: A Laissez Faire Approach by Colonel Brian M

Contracting in Conflicts: The Path to Reform

DTIC Science & Technology

2010-06-01

employment for local populations. By “hiring local,” the United States attempts to boost the local economy , reduce unemployment and drain away the...scores of consultations with officials from the Department of Defense, the Department of State and the U.S. Agency for International Development...journalists; officials from the International Committee of the Red Cross; academics; staff from the Congressional Research Service and the Government

ON A GENERALIZED SELF-SIMILARITY IN THE p-ADIC FIELD

NASA Astrophysics Data System (ADS)

Mukhamedov, Farrukh; Khakimov, Otabek

2016-08-01

In the present paper, we introduce a new set which defines a generalized self-similar set for contractive functions {fi}i=1N on the unit ball ℤp of p-adic numbers. This set is called unconventional limit set. We prove that the unconventional limit set is compact, perfect and uniformly disconnected. Moreover, we provide an example of two contractions for which the corresponding unconventional limiting set is quasi-symmetrically equivalent to the symbolic Cantor set.

41 CFR 109-1.5109 - Control of sensitive items.

Code of Federal Regulations, 2010 CFR

2010-07-01

... administrative control of sensitive items assigned for general use within an organizational unit as appropriate... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Control of sensitive...-INTRODUCTION 1.51-Personal Property Management Standards and Practices § 109-1.5109 Control of sensitive items...

Human Resource Development in the United Kingdom.

ERIC Educational Resources Information Center

1999

These four papers are from a symposium on human resource development (HRD) in the United Kingdom. "HRD and Psychological Contracts: A Case Study of Lifelong Learning" (Graeme Martin, Judy Pate, Jim McGoldrick) explores the influence of a lifelong learning program on employee perceptions of their psychological contracts in a longitudinal…

Muscle force loss and soreness subsequent to maximal eccentric contractions depend on the amount of fascicle strain in vivo.

PubMed

Guilhem, G; Doguet, V; Hauraix, H; Lacourpaille, L; Jubeau, M; Nordez, A; Dorel, S

2016-06-01

Defining the origins of muscle injury has important rehabilitation and exercise applications. However, current knowledge of muscle damage mechanics in human remains unclear in vivo. This study aimed to determine the relationships between muscle-tendon unit mechanics during maximal eccentric contractions and the extent of subsequent functional impairments induced by muscle damage. The length of the muscle-tendon unit, fascicles and tendinous tissues was continuously measured on the gastrocnemius medialis using ultrasonography, in time with torque, during 10 sets of 30 maximal eccentric contractions of plantar flexors at 45°s(-1) , in seventeen participants. Muscle-tendon unit, fascicles and tendinous tissues were stretched up to 4.44 ± 0.33 cm, 2.31 ± 0.64 cm and 1.92 ± 0.61 cm respectively. Fascicle stretch length, lengthening amplitude and negative fascicle work beyond slack length were significantly correlated with the force decrease 48 h post-exercise (r = 0.51, 0.47 and 0.68, respectively; P < 0.05). This study demonstrates that the strain applied to human muscle fibres during eccentric contractions strongly influences the magnitude of muscle damage in vivo. Achilles tendon compliance decreases the amount of strain, while architectural gear ratio may moderately contribute to attenuating muscle fascicle lengthening and hence muscle damage. Further studies are necessary to explore the impact of various types of task to fully understand the contribution of muscle-tendon interactions during active lengthening to muscle damage. © 2016 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd.

48 CFR 236.609-70 - Additional provision and clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

...—Restriction to United States Firms, in solicitations for A-E contracts that are— (1) Funded with military... Atlantic Treaty Organization member country, or in countries bordering the Arabian Gulf. [56 FR 36421, July...

Solid-waste contract-negotiation handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Environmental Protection Agency has estimated that the United States generated 164 million tons of municipal solid waste in 1986, and that the amount is increasing at a rate of more than 1 percent annually. Landfills are reaching capacity and closing. The cost of disposing of waste is growing and local officials are concerned about how they will meet the challenge of managing solid waste. This handbook is designed to help local officials develop contracts with private companies and other governmental units that will protect the interests of the citizens in their communities. This handbook is based on information andmore » analysis derived from a questionnaire survey of 160 local governments located in EPA Region X, plus selected other states; review and analysis of sample provisions from actual solid waste contracts and agreements; follow-up interviews with solid waste managers in several of the states and with responding local governments; and a review of the literature as well as state federal statutes and regulations.« less

48 CFR 6301.2 - Qualifications of members.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contract law. ... CONTRACT APPEALS BOARD OF CONTRACT APPEALS 6301.2 Qualifications of members. Each member of the Board must... administrative law judges appointed pursuant to section 3105 of title 5 of the United States Code, with the...

Contracting-out in the United Kingdom: a partnership between social security and private pension plans.

PubMed

Daykin, Chris

2002-01-01

Contracting-out was introduced in the United Kingdom in 1978 as part of the arrangements for the State Earnings-Related Pension Scheme (SERPS) in order to avoid duplication with the existing well-developed defined benefit occupational pension plan sector. Members and sponsors of contracted-out schemes were able to save on their social security contributions in recognition of the fact that they were accruing equivalent benefits through an occupational pension plan. Later on this concept was extended to those with individual money purchase pension plans. This article considers a brief history of contracting-out, the principles of contracting-out, some problems associated with contracting-out, the implications of the introduction of stakeholder pensions and State Second Pension, and the latest rebate review and rebate orders. It examines how U.K. pensions policy since 1978 has been based on a partnership between social security and private pension plans.

Motor Unit Activity during Fatiguing Isometric Muscle Contraction in Hemispheric Stroke Survivors

PubMed Central

McManus, Lara; Hu, Xiaogang; Rymer, William Z.; Suresh, Nina L.; Lowery, Madeleine M.

2017-01-01

Enhanced muscle weakness is commonly experienced following stroke and may be accompanied by increased susceptibility to fatigue. To examine the contributions of central and peripheral factors to isometric muscle fatigue in stroke survivors, this study investigates changes in motor unit (MU) mean firing rate, and action potential duration during, and directly following, a sustained submaximal fatiguing contraction at 30% maximum voluntary contraction (MVC). A series of short contractions of the first dorsal interosseous muscle were performed pre- and post-fatigue at 20% MVC, and again following a 10-min recovery period, by 12 chronic stroke survivors. Individual MU firing times were extracted using surface EMG decomposition and used to obtain the spike-triggered average MU action potential waveforms. During the sustained fatiguing contraction, the mean rate of change in firing rate across all detected MUs was greater on the affected side (-0.02 ± 0.03 Hz/s) than on the less-affected side (-0.004 ± 0.003 Hz/s, p = 0.045). The change in firing rate immediately post-fatigue was also greater on the affected side than less-affected side (-13.5 ± 20 and 0.1 ± 19%, p = 0.04). Mean MU firing rates increased following the recovery period on the less-affected side when compared to the affected side (19.3 ± 17 and 0.5 ± 20%, respectively, p = 0.03). MU action potential duration increased post-fatigue on both sides (10.3 ± 1.2 to 11.2 ± 1.3 ms on the affected side and 9.9 ± 1.7 to 11.2 ± 1.9 ms on the less-affected side, p = 0.001 and p = 0.02, respectively), and changes in action potential duration tended to be smaller in subjects with greater impairment (p = 0.04). This study presents evidence of both central and peripheral fatigue at the MU level during isometric fatiguing contraction for the first time in stroke survivors. Together, these preliminary observations indicate that the response to an isometric fatiguing contraction differs between the affected and less-affected side post-stroke, and may suggest that central mechanisms observed here as changes in firing rate are the dominant processes leading to task failure on the affected side. PMID:29225574

Age-related motor unit remodeling in the Tibialis Anterior.

PubMed

Siddiqi, Ariba; Kumar, Dinesh; Arjunan, Sridhar

2015-01-01

Limited studies exist on the use of surface electromyogram (EMG) signal features to detect age-related motor unit remodeling in the Tibialis Anterior. Motor unit remodeling leads to declined muscle strength and force steadiness during submaximal contractions which are factors for risk of falls in the elderly. This study investigated the remodeling phenomena in the Tibialis Anterior using sample entropy and higher order statistics. Eighteen young (26.1 ± 2.9 years) and twelve elderly (68.7 ± 9.0 years) participants performed isometric dorsiflexion of the ankle at 20% maximal voluntary contraction (MVC) and their Tibialis Anterior (TA) EMG was recorded. Sample entropy, Gaussianity and Linearity Test statistics were calculated from the recorded EMG for each MVC. Shapiro-Wilk test was used to determine normality, and either a two-tail student t-test or Wilcoxon rank sum test was performed to determine significant difference in the EMG features between the young and old cohorts. Results show age-related motor unit remodeling to be depicted by decreased sample entropy (p <; 0.1), increased non-Gaussianity (p <; 0.05) and lesser degree of linearity in the elderly. This is due to the increased sparsity of the MUAPs as a result of the denervation-reinnervation process, and the decrease in total number of motor units.