19 CFR 201.3 - Commission offices, mailing address, and hours.

Code of Federal Regulations, 2010 CFR

2010-04-01

.... 201.3 Section 201.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF... Commission's offices are located in the United States International Trade Commission Building on 500 E Street... the “Secretary, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436.” (c...

19 CFR 201.3 - Commission offices, mailing address, and hours.

Code of Federal Regulations, 2013 CFR

2013-04-01

.... 201.3 Section 201.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF... Commission's offices are located in the United States International Trade Commission Building on 500 E Street... the “Secretary, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436.” (c...

19 CFR 201.3 - Commission offices, mailing address, and hours.

Code of Federal Regulations, 2012 CFR

2012-04-01

.... 201.3 Section 201.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF... Commission's offices are located in the United States International Trade Commission Building on 500 E Street... the “Secretary, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436.” (c...

19 CFR 201.3 - Commission offices, mailing address, and hours.

Code of Federal Regulations, 2011 CFR

2011-04-01

.... 201.3 Section 201.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF... Commission's offices are located in the United States International Trade Commission Building on 500 E Street... the “Secretary, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436.” (c...

19 CFR 201.3 - Commission offices, mailing address, and hours.

Code of Federal Regulations, 2014 CFR

2014-04-01

.... 201.3 Section 201.3 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF... Commission's offices are located in the United States International Trade Commission Building on 500 E Street... the “Secretary, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436.” (c...

77 FR 14043 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

... UNITED STATES INTERNATIONAL TRADE COMMISSION [USITC SE-12-005] Government in the Sunshine Act Meeting Notice AGENCY: Agency Holding the Meeting: United States International Trade Commission. DATES: Time and Date: March 14, 2012 at 11 a.m. Place: Room 101, 500 E Street SW., Washington, DC 20436...

7 CFR 400.767 - Requester obligations.

Code of Federal Regulations, 2011 CFR

2011-01-01

....gov; or (iv) By overnight delivery to the Associate Administrator, Risk Management Agency, United... subpart must: (1) Be submitted: (i) In writing by certified mail, to the Associate Administrator, Risk Management Agency, United States Department of Agriculture, Stop Code 0801, 1400 Independence Avenue, SW...

7 CFR 400.767 - Requester obligations.

Code of Federal Regulations, 2010 CFR

2010-01-01

....gov; or (iv) By overnight delivery to the Associate Administrator, Risk Management Agency, United... subpart must: (1) Be submitted: (i) In writing by certified mail, to the Associate Administrator, Risk Management Agency, United States Department of Agriculture, Stop Code 0801, 1400 Independence Avenue, SW...

39 CFR 263.5 - Inquiries.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Inquiries. Inquiries regarding records maintenance and disposition should be directed to the Manager, Records Office, United States Postal Service, 475 L'Enfant Plaza, SW., Washington, DC 20260, or, by...

39 CFR 263.5 - Inquiries.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Inquiries. Inquiries regarding records maintenance and disposition should be directed to the Manager, Records Office, United States Postal Service, 475 L'Enfant Plaza, SW., Washington, DC 20260, or, by...

39 CFR 263.5 - Inquiries.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Inquiries. Inquiries regarding records maintenance and disposition should be directed to the Manager, Records Office, United States Postal Service, 475 L'Enfant Plaza, SW., Washington, DC 20260, or, by...

39 CFR 263.5 - Inquiries.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Inquiries. Inquiries regarding records maintenance and disposition should be directed to the Manager, Records Office, United States Postal Service, 475 L'Enfant Plaza, SW., Washington, DC 20260, or, by...

Carbon Mitigation Impacts of Increased Softwood Lumber and Structural Panel Use for Nonresidential Construction in the United States

Treesearch

Prakash Nepal; Kenneth E. Skog; David B. McKeever; Richard D. Bergman; Karen L. Abt; Robert C. Abt

2016-01-01

More wood use in the United States to construct low-rise nonresidential (NR) buildings would increase consumption and production of softwood (SW) lumber, engineered wood products, and structural and nonstructural wood panels. Using a consequential life-cycle analysis, we estimated the change in net CO2 emissions thatwould be caused by increased...

Depression in the Workplace

MedlinePlus

... on treatment for heart disease iv . The annual economic cost of depression in 1995 was $600 per ... Lowe SW, Berglund PA, Corey-Lisle PK. The economic burden of depression in the United States: how ...

Protective efficacy of a high-growth reassortant swine H3N2 inactivated vaccine constructed by reverse genetic manipulation

PubMed Central

Wen, Feng; Ma, Ji-Hong; Yang, Fu-Ru; Huang, Meng; Zhou, Yan-Jun; Li, Ze-Jun

2014-01-01

Novel reassortant H3N2 swine influenza viruses (SwIV) with the matrix gene from the 2009 H1N1 pandemic virus have been isolated in many countries as well as during outbreaks in multiple states in the United States, indicating that H3N2 SwIV might be a potential threat to public health. Since southern China is the world's largest producer of pigs, efficient vaccines should be developed to prevent pigs from acquiring H3N2 subtype SwIV infections, and thus limit the possibility of SwIV infection at agricultural fairs. In this study, a high-growth reassortant virus (GD/PR8) was generated by plasmid-based reverse genetics and tested as a candidate inactivated vaccine. The protective efficacy of this vaccine was evaluated in mice by challenging them with another H3N2 SwIV isolate [A/Swine/Heilongjiang/1/05 (H3N2) (HLJ/05)]. Prime and booster inoculation with GD/PR8 vaccine yielded high-titer serum hemagglutination inhibiting antibodies and IgG antibodies. Complete protection of mice against H3N2 SwIV was observed, with significantly reduced lung lesion and viral loads in vaccine-inoculated mice relative to mock-vaccinated controls. These results suggest that the GD/PR8 vaccine may serve as a promising candidate for rapid intervention of H3N2 SwIV outbreaks in China. PMID:24675833

Streetworkers, youth violence prevention, and peacemaking in Lowell, Massachusetts: lessons and voices from the community.

PubMed

Frattaroli, Shannon; Pollack, Keshia M; Jonsberg, Karen; Croteau, Gregg; Rivera, JuanCarlos; Mendel, Jennifer S

2010-01-01

Communities across the United States are using street outreach workers (SWs) to prevent violence. SW programs are generally recognized as a promising model, particularly in light of a 2008 evaluation that demonstrated positive impacts associated with one well-known program. The United Teen Equality Center (UTEC) includes an SW program. Through this paper we aim to (1) document the work of the UTEC SWs, (2) describe UTEC's approach to training SWs and managing the program, and (3) understand interviewees' perspectives (including UTEC managers, SWs and partners) on how the SWs impact youth violence in Lowell. We designed a single-site observational study using qualitative methods to address our study aims. We collected data from in-person, semistructured interviews with the two UTEC SW program managers, the six SWs employed during the study period, and 17 representatives from partner agencies. UTEC SWs outreach to youth, respond to crises in the lives of youth as opportunity, work to facilitate access to resources for youth, and engage in intensive follow-up with youth when needed. These findings are consistent with UTEC's pyramid model of SW outreach. The program emphasizes peacemaking (not only preventing violence) and partnerships as priorities. SWs participate in structured training, receive a comprehensive benefits package, and have opportunities for professional development. Several aspects of UTEC's program may be useful for other SW programs: Involve youth in hiring SWs, invest in SW training, incorporate peacemaking strategies into outreach, and partner with agencies that also serve youth.

19 CFR 213.6 - Information concerning assistance.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

19 CFR 213.6 - Information concerning assistance.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

19 CFR 213.6 - Information concerning assistance.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

19 CFR 213.6 - Information concerning assistance.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 213.6 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.6 Information concerning assistance. Any person may.... International Trade Commission, 500 E Street SW., Washington, DC 20436. ...

Investigating Ecosystems Services in the Arid Southwest

EPA Science Inventory

The Southwest Ecosystem Services Project (SwESP) is an integrated, multi-disciplinary, multi-agency project focused on how to identify, characterize, and quantify the ecosystem services in the southwestern United States and northern Mexico. The southwestern landscape is highly d...

19 CFR 213.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

19 CFR 213.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

19 CFR 213.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

19 CFR 213.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE TRADE REMEDY ASSISTANCE § 213.2 Definitions. (a) Office. The Trade Remedy Assistance Office (hereinafter Office... Trade Remedy Assistance Office, U.S. International Trade Commission, 500 E Street SW., Washington, DC...

33 CFR 117.305 - Miami River.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the United States, tugs, tugs with tows, and vessels in a situation where a delay would endanger life... section at any time. (b) The draws of the S.W. First Street Bridge, mile 0.9, up to and including the N.W...

INDEPENDENT TECHNICAL REVIEW OF THE FOCUSED FEASIBILITY STUDY AND PROPOSED PLAN FOR DESIGNATED SOLID WASTE MANAGEMENT UNITS CONTRIBUTING TO THE SOUTHWEST GROUNDWATER PLUME AT THE PADUCAH GASEOUS DIFFUSION PLANT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney, B.; Eddy-Dilek, C.; Amidon, M.

2011-05-31

The U. S. Department of Energy (DOE) is currently developing a Proposed Plan (PP) for remediation of designated sources of chlorinated solvents that contribute contamination to the Southwest (SW) Groundwater Plume at the Paducah Gaseous Diffusion Plant (PGDP), in Paducah, KY. The principal contaminants in the SW Plume are trichloroethene (TCE) and other volatile organic compounds (VOCs); these industrial solvents were used and disposed in various facilities and locations at PGDP. In the SW plume area, residual TCE sources are primarily in the fine-grained sediments of the Upper Continental Recharge System (UCRS), a partially saturated zone that delivers contaminants downwardmore » into the coarse-grained Regional Gravel Aquifer (RGA). The RGA serves as the significant lateral groundwater transport pathway for the plume. In the SW Plume area, the four main contributing TCE source units are: (1) Solid Waste Management Unit (SWMU) 1 / Oil Landfarm; (2) C-720 Building TCE Northeast Spill Site (SWMU 211A); (3) C-720 Building TCE Southeast Spill Site (SWMU 211B); and (4) C-747 Contaminated Burial Yard (SWMU 4). The PP presents the Preferred Alternatives for remediation of VOCs in the UCRS at the Oil Landfarm and the C-720 Building spill sites. The basis for the PP is documented in a Focused Feasibility Study (FFS) (DOE, 2011) and a Site Investigation Report (SI) (DOE, 2007). The SW plume is currently within the boundaries of PGDP (i.e., does not extend off-site). Nonetheless, reasonable mitigation of the multiple contaminant sources contributing to the SW plume is one of the necessary components identified in the PGDP End State Vision (DOE, 2005). Because of the importance of the proposed actions DOE assembled an Independent Technical Review (ITR) team to provide input and assistance in finalizing the PP.« less

77 FR 46684 - In the Matter of: Universal Industries Limited, Inc., 3050 SW 14th Place Unit 3, Boynton Beach...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-06

... export from the United States to Singapore military aircraft parts, that is approximately 200 J-85 Stage... owned, possessed or controlled by the Denied Person, or service any item, of whatever origin, that is... the foreign-produced direct product of U.S.-origin technology. V. This Order is effective immediately...

Inline Monitoring of Free Water and Particulate Contamination of Jet A Fuel

DTIC Science & Technology

2015-04-10

authors expressed herein do not necessarily state or reflect those of the United States Government or the DoA, and shall not be used for advertising or...3.1 PROGENY Joel Schmitigal (TARDEC) and Mike Strong and David Beers (Progeny Systems Corporation) visited SwRI the week of 04 November 2013 to

10 CFR 1015.101 - Prescription of standards.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Prescription of standards. 1015.101 Section 1015.101 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COLLECTION OF CLAIMS OWED THE UNITED STATES General... (DOE) Office of Financial Policy, 1000 Independence Ave., SW., Washington, DC 20585. (b) Additional...

10 CFR 1015.101 - Prescription of standards.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Prescription of standards. 1015.101 Section 1015.101 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COLLECTION OF CLAIMS OWED THE UNITED STATES General... (DOE) Office of Financial Policy, 1000 Independence Ave., SW., Washington, DC 20585. (b) Additional...

10 CFR 1015.101 - Prescription of standards.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Prescription of standards. 1015.101 Section 1015.101 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COLLECTION OF CLAIMS OWED THE UNITED STATES General... (DOE) Office of Financial Policy, 1000 Independence Ave., SW., Washington, DC 20585. (b) Additional...

10 CFR 1015.101 - Prescription of standards.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Prescription of standards. 1015.101 Section 1015.101 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COLLECTION OF CLAIMS OWED THE UNITED STATES General... (DOE) Office of Financial Policy, 1000 Independence Ave., SW., Washington, DC 20585. (b) Additional...

Varying geospatial analyses to assess climate risk and adaptive capacity in a hotter, drier Southwestern United States

NASA Astrophysics Data System (ADS)

Elias, E.; Reyes, J. J.; Steele, C. M.; Rango, A.

2017-12-01

Assessing vulnerability of agricultural systems to climate variability and change is vital in securing food systems and sustaining rural livelihoods. Farmers, ranchers, and forest landowners rely on science-based, decision-relevant, and localized information to maintain production, ecological viability, and economic returns. This contribution synthesizes a collection of research on the future of agricultural production in the American Southwest (SW). Research was based on a variety of geospatial methodologies and datasets to assess the vulnerability of rangelands and livestock, field crops, specialty crops, and forests in the SW to climate-risk and change. This collection emerged from the development of regional vulnerability assessments for agricultural climate-risk by the U.S. Department of Agriculture (USDA) Climate Hub Network, established to deliver science-based information and technologies to enable climate-informed decision-making. Authors defined vulnerability differently based on their agricultural system of interest, although each primarily focuses on biophysical systems. We found that an inconsistent framework for vulnerability and climate risk was necessary to adequately capture the diversity, variability, and heterogeneity of SW landscapes, peoples, and agriculture. Through the diversity of research questions and methodologies, this collection of articles provides valuable information on various aspects of SW vulnerability. All articles relied on geographic information systems technology, with highly variable levels of complexity. Agricultural articles used National Agricultural Statistics Service data, either as tabular county level summaries or through the CropScape cropland raster datasets. Most relied on modeled historic and future climate information, but with differing assumptions regarding spatial resolution and temporal framework. We assert that it is essential to evaluate climate risk using a variety of complementary methodologies and perspectives. In addition, we found that spatial analysis supports informed adaptation, within and outside the SW United States. The persistence and adaptive capacity of agriculture in the water-limited Southwest serves as an instructive example and may offer solutions to reduce future climate risk.

77 FR 34997 - Xanthan Gum From Austria and China; Institution of Antidumping Duty Investigations and Scheduling...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-12

... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 731-TA-1202-1203 (Preliminary)] Xanthan Gum... Phase Investigations AGENCY: United States International Trade Commission. ACTION: Notice. SUMMARY: The... Investigations, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436. Hearing-impaired...

19 CFR 210.56 - Notice accompanying service copies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 210.56 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES... temporary relief will be filed with the U.S. International Trade Commission in Washington, DC on ____, 20... Investigations, U.S. International Trade Commission, 500 E Street SW., Room 401, Washington, DC 20436, telephone...

76 FR 37890 - Certification Pursuant to Energy Policy Act of 2005

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-28

... AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice. SUMMARY: The Energy... CONTACT: Teresa Dawson, Senior Counsel, Financial Management Service, 401 14th Street, SW., Washington, DC... October 2006 the Minerals Management Service (MMS) of the United States Department of the Interior entered...

78 FR 44043 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

...-0635; Directorate Identifier 2012-SW-081-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... France and are approved for operation in the United States. Pursuant to our bilateral agreement with...

77 FR 44509 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

...-0795; Directorate Identifier 2008-SW-53-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... by the aviation authority of the France and are approved for operation in the United States. Pursuant...

78 FR 33764 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

...-0479; Directorate Identifier 2011-SW-070-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement...

77 FR 36216 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

...-0631; Directorate Identifier 2011-SW-021-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

78 FR 51115 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-20

...-0737; Directorate Identifier 2012-SW-111-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France (Eurocopter... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

78 FR 66668 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-06

...-0938; Directorate Identifier 2012-SW-057-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

39 CFR 265.5 - Public reading rooms.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Public reading rooms. 265.5 Section 265.5 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.5 Public reading rooms. The Library of the Postal Service Headquarters, 475 L'Enfant Plaza SW, Washington, DC 20260...

77 FR 55861 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-11

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-025] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: September 12, 2012 at 9:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

77 FR 45376 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-023] Sunshine Act Meeting AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: August 9, 2012 at 1:00 p.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS: Open to the public. MATTERS...

78 FR 41421 - Certain Oil Country Tubular Goods From India, Korea, Philippines, Saudi Arabia, Taiwan, Thailand...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-10

... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-499-500 and 731-TA-1215-1223... Scheduling of Preliminary Phase Investigations AGENCY: United States International Trade Commission. ACTION...-205-3169), Office of Investigations, U.S. International Trade Commission, 500 E Street SW., Washington...

77 FR 45377 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-022] Sunshine Act Meeting AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: August 8, 2012 at 1:00 p.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS: Open to the public. MATTERS...

78 FR 76321 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-17

... INTERNATIONAL TRADE COMMISSION [USITC SE-13-038] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: December 17, 2013 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

78 FR 9427 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-08

... INTERNATIONAL TRADE COMMISSION [USITC SE-13-007] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission TIME AND DATE: February 15, 2013 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

77 FR 67395 - Corrosion-Resistant Carbon Steel Flat Products From Germany and Korea; Revised Schedule for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-09

... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-350 and 731-TA-616 and 618 (Third Review... Reviews AGENCY: United States International Trade Commission. ACTION: Notice. DATES: Effective Date....S. International Trade Commission, 500 E Street SW., Washington, DC 20436. Hearing-impaired persons...

Vegetation productivity responds to sub-annual climate conditions across semiarid biomes

USDA-ARS?s Scientific Manuscript database

In the Southwestern United States (SW), the current prolonged warm drought is similar to the predicted future climate change scenarios for the region. This study aimed to determine patterns in vegetation response to the early 21st century drought across multiple biomes. We hypothesized that differen...

76 FR 39122 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-018] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: July 8, 2011 at 9:30 a.m. PLACE: Room 110, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000...

77 FR 69658 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

... INTERNATIONAL TRADE COMMISSION Government in the Sunshine Act Meeting Notice [USITC SE-12-033] AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: November 27, 2012 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

77 FR 44672 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-020] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: July 31, 2012 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS...

76 FR 17966 - Government In the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-008] Government In the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: April 12, 2011 at 11 a.m. PLACE: Room 110, 500 E Street, SW., Washington, DC 20436. Telephone: (202) 205-2000...

76 FR 22146 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-20

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-010] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: April 28, 2011 at 11 a.m. PLACE: Room 110, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS...

76 FR 54791 - Government In the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-02

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-024] Government In the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: September 9, 2011 at 11 a.m. PLACE: Room 101, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000...

75 FR 13573 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-22

... INTERNATIONAL TRADE COMMISSION [USITC SE-10-004] Government in the Sunshine Act Meeting Notice Agency Holding the Meeting: United States International Trade Commission. Time and Date: March 26, 2010 at 11 a.m. Place: Room 101, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000...

76 FR 25709 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-011] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: May 13, 2011 at 11 a.m. PLACE: Room 110, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS...

76 FR 56222 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-025] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: September 14, 2011 at 2 p.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436. Telephone: (202) 205-2000...

76 FR 52013 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-19

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-023] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: August 30, 2011 at 11 a.m. PLACE: Room 101, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000...

76 FR 44358 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-25

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-020] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: July 27, 2011 at 11 a.m. PLACE: Room 101, 500 E Street, SW., Washington, DC 20436. Telephone: (202) 205-2000. STATUS...

77 FR 75658 - Government In the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-034] Government In the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: December 28, 2012 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

78 FR 40507 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

... INTERNATIONAL TRADE COMMISSION [USITC SE-13-016] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: July 10, 2013 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS...

76 FR 66751 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-27

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-029] Government in the Sunshine Act Meeting Notice Agency Holding The Meeting: United States International Trade Commission. Time And Date: November 3, 2011 at 2 p.m. Place: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000. Status...

78 FR 49545 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-14

... INTERNATIONAL TRADE COMMISSION [USITC SE-13-019] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: August 19, 2013 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

76 FR 28241 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-16

... INTERNATIONAL TRADE COMMISSION Government in the Sunshine Act Meeting Notice [USITC SE-11-013] AGENCY: United States International Trade Commission. TIME AND DATE: May 19, 2011 at 11 a.m. PLACE: Room 110, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS: Open to the public...

75 FR 64742 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-20

... INTERNATIONAL TRADE COMMISSION [USITC SE-10-029] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: October 22, 2010 at 2 p.m. PLACE: Room 101, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS...

77 FR 48170 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-13

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-024] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: August 21, 2012 at 9:30 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

78 FR 55296 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-10

... INTERNATIONAL TRADE COMMISSION [USITC SE-13-023] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: September 20, 2013 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

77 FR 44672 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-021] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: August 2, 2012 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

78 FR 20686 - Federal Property Suitable as Facilities To Assist the Homeless

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-05

...-8145; Coast Guard: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

75 FR 60777 - Federal Property Suitable as Facilities To Assist the Homeless

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-01

...: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St., SW., Stop 7901, Washington... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for possible use to assist the homeless. FOR...

77 FR 43738 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

...-0772; Directorate Identifier 2007-SW-053-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... manufactured in France and is type certificated for operation in the United States under the provisions of 14...

78 FR 47230 - Airworthiness Directives; Eurocopter France (Eurocopter) Model Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

...-0679; Directorate Identifier 2009-SW-015-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the unsafe condition described...

77 FR 11787 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-28

...-0177; Directorate Identifier 2009-SW-59-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model EC155B and... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

78 FR 33766 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

...-0480; Directorate Identifier 2012-SW-090-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the...

Maximizing Autonomy: Reforming Personal Support Laws in Sweden and the United States.

ERIC Educational Resources Information Center

Herr, Stanley S.

1995-01-01

Forms of guardianship for U.S. individuals with disabilities are reviewed, and Swedish legal and public policy innovations that replace guardianship with personal support services, such as mentors and personal assistants, are considered. The impact of Sweden's reforms on autonomy, independence, and integration is addressed. (Author/SW)

40 CFR Appendix to Part 246 - Recommended Bibliography

Code of Federal Regulations, 2011 CFR

2011-07-01

... Belknap, M. Paper recycling: a business perspective. Subcommittee on Solid Waste, New York Chamber of... Publication SW-155. Washington, U.S. Government Printing Office, 1975. 26 p. Hansen, P. Solid waste recycling... Printing Office, 1973. 284 p. Lingle, S. A. Paper recycling in the United States. Washington, U.S...

40 CFR Appendix to Part 246 - Recommended Bibliography

Code of Federal Regulations, 2010 CFR

2010-07-01

... Belknap, M. Paper recycling: a business perspective. Subcommittee on Solid Waste, New York Chamber of... Publication SW-155. Washington, U.S. Government Printing Office, 1975. 26 p. Hansen, P. Solid waste recycling... Printing Office, 1973. 284 p. Lingle, S. A. Paper recycling in the United States. Washington, U.S...

40 CFR Appendix to Part 246 - Recommended Bibliography

Code of Federal Regulations, 2012 CFR

2012-07-01

... Belknap, M. Paper recycling: a business perspective. Subcommittee on Solid Waste, New York Chamber of... Publication SW-155. Washington, U.S. Government Printing Office, 1975. 26 p. Hansen, P. Solid waste recycling... Printing Office, 1973. 284 p. Lingle, S. A. Paper recycling in the United States. Washington, U.S...

40 CFR Appendix to Part 246 - Recommended Bibliography

Code of Federal Regulations, 2013 CFR

2013-07-01

... Belknap, M. Paper recycling: a business perspective. Subcommittee on Solid Waste, New York Chamber of... Publication SW-155. Washington, U.S. Government Printing Office, 1975. 26 p. Hansen, P. Solid waste recycling... Printing Office, 1973. 284 p. Lingle, S. A. Paper recycling in the United States. Washington, U.S...

40 CFR Appendix to Part 246 - Recommended Bibliography

Code of Federal Regulations, 2014 CFR

2014-07-01

... Belknap, M. Paper recycling: a business perspective. Subcommittee on Solid Waste, New York Chamber of... Publication SW-155. Washington, U.S. Government Printing Office, 1975. 26 p. Hansen, P. Solid waste recycling... Printing Office, 1973. 284 p. Lingle, S. A. Paper recycling in the United States. Washington, U.S...

75 FR 31279 - Blueberry Promotion, Research, and Information Order; Increase Membership

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service 7 CFR Part 1218 [Document Number AMS-FV... Programs, AMS, U.S. Department of Agriculture, Stop 0244, 1400 Independence Avenue, SW., Room 0632-S... 2008, the United States exported 13,791 metric tons of fresh highbush blueberries worth over $69...

77 FR 66631 - Government in The Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-06

... INTERNATIONAL TRADE COMMISSION [USITC SE-12-029] Government in The Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: November 9, 2012 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

76 FR 62444 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-07

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-027] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission, TIME AND DATE: October 12, 2011 at 9:30 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

78 FR 48192 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-07

... INTERNATIONAL TRADE COMMISSION [USITC SE-13-017] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: August 9, 2013 at 11:00 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000...

76 FR 79710 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-22

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-039] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: January 5, 2012 at 11 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS...

76 FR 69763 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-09

... INTERNATIONAL TRADE COMMISSION [USITC SE-11-032] Government in the Sunshine Act Meeting Notice AGENCY: Agency Holding the Meeting: United States International Trade Commission. DATES: Time and Date: November 17, 2011 at 11 a.m. Place: Room 100, 500 E Street SW., Washington, DC 20436, Telephone: (202) 205...

[Phylogenetic analysis of human/swine/avian gene reassortant H1N2 influenza A virus isolated from a pig in China].

PubMed

Chen, Yixiang; Meng, Xueqiong; Liu, Qi; Huang, Xia; Huang, Shengbin; Liu, Cuiquan; Shi, Kaichuang; Guo, Jiangang; Chen, Fangfang; Hu, Liping

2008-04-01

Our aim in this study was to determine the genetic characterization and probable origin of the H1N2 swine influenza virus (A/Swine/Guangxi/13/2006) (Sw/GX/13/06) from lung tissue of a pig in Guangxi province, China. Eight genes of Sw/GX/13/06 were cloned and genetically analyzed. The hemagglutinin (HA), nucleoprotein (NP), matrix (M) and non-structural (NS) genes of Sw/GX/13/06 were most closely related to genes from the classical swine H1N1 influenza virus lineage. The neuraminidase (NA) and PB1 genes were most closely related to the corresponding genes from the human influenza H3N2 virus lineage. The remaining two genes PA and PB2 polymerase genes were most closely related to the genes from avian influenza virus lineage. Phylogenetic analyses revealed that Sw/GX/13/06 was a human/swine/avian H1N2 virus, and closely related to H1N2 viruses isolated from pigs in United States (1999-2001) and Korea (2002). To our knowledge, Sw/GX/13/06 was the first triple-reassortant H1N2 influenza A virus isolated from a pig in China. Whether the Sw/GX/13/06 has a potential threat to breeding farm and human health remains to be further investigated.

78 FR 66950 - Trade Barriers That U.S. Small and Medium-Sized Enterprises Perceive as Affecting Exports to the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... INTERNATIONAL TRADE COMMISSION [Investigation No. 332-541] Trade Barriers That U.S. Small and.... ADDRESSES: All written submissions should be addressed to the Secretary, United States International Trade... held at the U.S. International Trade Commission Building, 500 E Street SW., Washington, DC, beginning...

78 FR 76177 - Sunshine Act Meeting Notice; Change of Time of Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

... INTERNATIONAL TRADE COMMISSION [USITC SE-13-036] Sunshine Act Meeting Notice; Change of Time of Sunshine Act Meeting AGENCY HOLDING THE MEETING: United States International Trade Commission. DATE: December 13, 2013. NEW TIME: 9:30 a.m. PLACE: Room 101, 500 E Street SW., Washington, DC 20436, Telephone...

78 FR 63429 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

...-0872; Directorate Identifier 2013-SW-012-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model AS332C, AS332L... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

Acceleration Response Mode Decomposition for Quantifying Wave Impact Load in High-Speed Planing Craft

DTIC Science & Technology

2014-04-01

Chicago , San Francisco, 1996 6. Savitsky, Daniel and Brown, P.W., “Procedures for Hydrodynamic Evaluation of Planing Hulls in Smooth and Rough Water...20593-7356 Attn: David Shepard United States Coast Guard RDT&E Division 2100 Second Street, SW STOP 7111 Washington, DC 20593-7111 Attn: Frank

The Simulation of Wave Slam Impulses to Evaluate Shock Mitigation Seats For High-Speed Planing Craft

DTIC Science & Technology

2013-05-17

Vibration Handbook Fourth Edition”, McGraw Hill, New York, Chicago , San Francisco, 1996 29. Riley, M., Coats, T., Haupt, K., Jacobson, D., “The...United States Coast Guard Office of Boat Forces, CG 731 2100 Second Street, SW STOP 356 Washington, DC 20593-7356 Attn: David Shepard

Looking for Trouble: A Policymaker’s Guide to Biosensing

DTIC Science & Technology

2004-06-01

impacted the continental United States and Canada include Legionnaires ’ disease (1977), HIV/AIDS (1981), West Nile virus (1999), and SARS (2003...5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME... S ) AND ADDRESS(ES) National Defense University,Center for Technology and National Security Policy,300 5th Avenue SW, Fort Lesley J. McNair,Washington

75 FR 55827 - Government in the Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-14

... INTERNATIONAL TRADE COMMISSION [USITC SE-10-027] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: September 20, 2010 at 1 p.m. PLACE: Room 101, 500 E Street, SW., Washington, DC 20436, Telephone: (202) 205-2000. STATUS: Open to the public. MATTERS TO BE...

Assessment of the effect of air pollution controls on trends in shortwave radiation over the United States from 1995 through 2010 from multiple observation networks

EPA Science Inventory

Long-term data sets of all-sky and clear-sky downwelling shortwave (SW) radiation, cloud cover fraction, and aerosol optical depth (AOD) were analyzed together with surface concentrations from several networks (e.g., Surface Radiation Budget Network (SURFRAD), Clean Air Status an...

A Guide for Measuring, Analyzing, and Evaluating Accelerations Recorded During Seakeeping Trials of High-Speed Craft

DTIC Science & Technology

2016-01-01

Smith, Strether. Digital Data Acquisition and Analysis, A short course presented at Sensors Expo Chicago , June 9, 2008. 11. Judd, Bob, Everything You...Forces, CG 731 2100 Second Street, SW STOP 356 Washington, DC 20593-7356 Attn: David Shepard United States Coast Guard RDT&E Division 2100 Second

CT visible internal stone structure, but not Hounsfield unit value, of calcium oxalate monohydrate (COM) calculi predicts lithotripsy fragility in vitro.

PubMed

Zarse, Chad A; Hameed, Tariq A; Jackson, Molly E; Pishchalnikov, Yuri A; Lingeman, James E; McAteer, James A; Williams, James C

2007-08-01

Calcium oxalate monohydrate (COM) stones are often resistant to breakage using shock wave (SW) lithotripsy. It would be useful to identify by computed tomography (CT) those COM stones that are susceptible to SW's. For this study, 47 COM stones (4-10 mm in diameter) were scanned with micro CT to verify composition and also for assessment of heterogeneity (presence of pronounced lobulation, voids, or apatite inclusions) by blinded observers. Stones were then placed in water and scanned using 64-channel helical CT. As with micro CT, heterogeneity was assessed by blinded observers, using high-bone viewing windows. Then stones were broken in a lithotripter (Dornier Doli-50) over 2 mm mesh, and SW's counted. Results showed that classification of stones using micro CT was highly repeatable among observers (kappa = 0.81), and also predictive of stone fragility. Stones graded as homogeneous required 1,874 +/- 821 SW/g for comminution, while stones with visible structure required half as many SW/g, 912 +/- 678. Similarly, when stones were graded by appearance on helical CT, classification was repeatable (kappa = 0.40), and homogeneous stones required more SW's for comminution than did heterogeneous stones (1,702 +/- 993 SW/g, compared to 907 +/- 773). Stone fragility normalized to stone size did not correlate with Hounsfield units (P = 0.85). In conclusion, COM stones of homogeneous structure require almost twice as many SW's to comminute than stones of similar mineral composition that exhibit internal structural features that are visible by CT. This suggests that stone fragility in patients could be predicted using pre-treatment CT imaging. The findings also show that Hounsfield unit values of COM stones did not correlate with stone fragility. Thus, it is stone morphology, rather than X-ray attenuation, which correlates with fragility to SW's in this common stone type.

Using SW4 for 3D Simulations of Earthquake Strong Ground Motions: Application to Near-Field Strong Motion, Building Response, Basin Edge Generated Waves and Earthquakes in the San Francisco Bay Are

NASA Astrophysics Data System (ADS)

Rodgers, A. J.; Pitarka, A.; Petersson, N. A.; Sjogreen, B.; McCallen, D.; Miah, M.

2016-12-01

Simulation of earthquake ground motions is becoming more widely used due to improvements of numerical methods, development of ever more efficient computer programs (codes), and growth in and access to High-Performance Computing (HPC). We report on how SW4 can be used for accurate and efficient simulations of earthquake strong motions. SW4 is an anelastic finite difference code based on a fourth order summation-by-parts displacement formulation. It is parallelized and can run on one or many processors. SW4 has many desirable features for seismic strong motion simulation: incorporation of surface topography; automatic mesh generation; mesh refinement; attenuation and supergrid boundary conditions. It also has several ways to introduce 3D models and sources (including Standard Rupture Format for extended sources). We are using SW4 to simulate strong ground motions for several applications. We are performing parametric studies of near-fault motions from moderate earthquakes to investigate basin edge generated waves and large earthquakes to provide motions to engineers study building response. We show that 3D propagation near basin edges can generate significant amplifications relative to 1D analysis. SW4 is also being used to model earthquakes in the San Francisco Bay Area. This includes modeling moderate (M3.5-5) events to evaluate the United States Geologic Survey's 3D model of regional structure as well as strong motions from the 2014 South Napa earthquake and possible large scenario events. Recently SW4 was built on a Commodity Technology Systems-1 (CTS-1) at LLNL, new systems for capacity computing at the DOE National Labs. We find SW4 scales well and runs faster on these systems compared to the previous generation of LINUX clusters.

Retrospective analysis of seasonal ocean growth rates of two sea winter Atlantic Salmon in eastern Maine using historic scales

USGS Publications Warehouse

Izzo, Lisa K.; Zydlewski, Joseph D.

2017-01-01

Substantial declines of anadromous Atlantic Salmon Salmo salar have occurred throughout its range, with many populations at the southern extent of the distribution currently extirpated or endangered. While both one sea winter (1SW) and two sea winter (2SW) spawner numbers for the North American stocks have declined since the 1950s, the decline has been most severe in 2SW spawners. The first months at sea are considered a period of high mortality. However, early ocean mortality alone cannot explain the more pronounced decline of 2SW spawners, suggesting that the second year at sea may be more critical than previously thought. Atlantic Salmon scales collected by anglers and the state agency from 1946 to 2013 from five rivers in eastern Maine were used to estimate smolt age and ocean age of returning adults. Additionally, seasonal growth rates of maiden 2SW spawners were estimated using intercirculi measurements and linear back-calculation methods. Generalized linear mixed models (Gaussian family, log link function) were used to investigate the influence of average sea surface temperature, accumulated thermal units, the Atlantic Multidecadal Oscillation (AMO) and North Atlantic Oscillation indices, smolt age, smolt length, postsmolt growth, and river of origin on growth rate during the oceanic migration of North American Atlantic Salmon. Results suggest that different factors influence salmon growth throughout their oceanic migration, and previous growth can be a strong predictor of future size. Growth was negatively impacted by the phase of the AMO, which has been linked to salmon abundance trends, in early spring following the postsmolt period. This is likely when the 1SW and 2SW stock components separate, and our results suggest that this period may be of interest in future work examining the disproportionate decline in 2SW spawners.

Post-Panafrican late Proterozoic basins in the Central Anti-Atlas (Morocco): their influence on the Variscan contractional structures.

NASA Astrophysics Data System (ADS)

Guimerà, Joan; Arboleya, María. Luisa

2010-05-01

Located South of the High Atlas, in Morocco, The Anti-Atlas is a 700 km-long chain trending NE-SW. In the Central Anti-Atlas region, between Warzazat and Taznakht, the Proterozoic Pan-African basement (X1 to X2-3) crops out in isolated areas (boutonnières), where it is overlaid by late to post Pan-African Upper Proterozoic and Palaeozoic rocks. Late to post Pan-African Upper Proterozoic rocks (X3) have been classically divided into three units (X3i, X3m and X3s) which include volcanic rocks — mainly rhyolites— and continental siliciclastic rocks, the older units intruded by late granites (Choubert, 1952 and Choubert et al., 1970). Rocks belonging to the upper unit of post Pan-African Upper Proterozoic rocks (X3s) were deposited in basins bounded by faults with a dominant dip-slip normal motion; as a result, this unit have a variable thickness, being locally absent in the uplifted blocks. Uppermost Proterozoic (Adoudounian) and Palaeozoic rocks deposited unconformable on the older rocks in the Anti-Atlas. The Central Anti-Atlas was slightly deformed during the Variscan orogeny by folds and high-angle thrusts. Two areas are selected to study the post Pan-African to Variscan evolution of the area: the Tiwiyyine basin and the Anti-Atlas Major Fault. Tiwiyyine basin This basin is delimited by kilometric-scale normal faults. Three of them can be observed in the field: two striking NE-SW (NW and SE boundaries) and one striking NW-SE (SW boundary), while the NE boundary is covered by Cenozoic rocks. The basin fill reaches 725 m and has been divided into three units: 1. X3s1: Coarse conglomerates with basal breccias. 2. X3s2: Laminated dolomites at the base, red pelites and conglomerates. 3. X3s3: Conglomerates with interbedded andesites. Unit X3s2 passes laterally to the SW to unit X3s1. The thickness of the basin fill diminishes to the SE. This is specially visible at the basal X3s1 unit. At both sides of the two NE-SW-striking faults, only the upper X3s3 unit is found, while none of the three units is observed SW of the NW-SE- striking fault. The substratum of the X3s unit inside and outside the Tiwiyyine basin is the X3m unit. Extension along two NW-SE cross-sections is 7.2 % and 8.3 %. Along a section oriented NE-SW the calculated extension is 5.1 %, although only one boundary fault has been taken into account. During the Variscan orogeny the Tiwiyyine basin underwent a contractional deformation that caused the inversion of the normal faults bounding the basin, and the formation of folds parallel to them. The inversion of the two NE-SW-striking faults caused the substratum of the basin to crop out in their hanging wall. In the SW segment of the basin, the NW-SE fault was not inverted and the base of the Adoudounian still covers the fault. In the hanging wall of this fault a NW striking fold appeared, that beyond the basin becomes a SW-vergent reverse fault. A NW-SE syncline, visible in the Adoudounian rocks, formed to the SW, in the footwall of the fault. The horizontal shortening along the two NW-SE cross-sections is 14.8 % and 12.7 %. The shortening along the section oriented NE-SW is 2.8 %, although, as stated previously, only one boundary fault has been taken into account. From these data, horizontal shortening in all directions can be deduced, evidenced by the map recognition of sinusoidal fold traces and three-limb synclines. These patterns are typically the result of synchronous cross-folding with different amounts of shortening in different directions (Gosh and Ramberg, 1968). We interpret these structures to be originated by an unique episode of horizontal constriction. Anti-Atlas Major Fault The Anti-Atlas Major Fault (AMF) is a structure inherited from the Panafrican orogeny. It has been proposed even as the Panafrican continental suture (Leblanc, 1976). North of Taznakht the AMF appears as a North-dipping fault that experienced a normal slip during the sedimentation of the X3s unit, as can be deduced from the presence of this unit in its hanging-wall while it is absent in its footwall. Adoudounian and Palaeozoic rocks lie unconformable on both blocks of the fault, but they were affected by part of the normal slip of the AMF, which can be observed along several kilometres, putting in contact Adoudounian rocks in the hanging wall to X2 and X3i in the foot-wall. To the east, the AMF shows a reverse slip at surface, and the Adoudounian rocks of the hanging wall are thrust onto those of the footwall. The minimum Variscan shortening is estimated to be about 9% in a NNE-SSW direction. Summarizing, the AMF had two episodes of normal slip (one during the sedimentation of X3s and another involving the Palaeozoic rocks), and a late episode of reverse inversion during the Variscan orogeny. The Variscan reverse slip was less than the previous normal one, with only the Adoudounian level, in the eastern part of the sector studied, recuperating the previous downthrowing. REFERENCES Choubert, G. (1952): Histoire Géologique du domaine de l'Anti-Atlas. Géologie du Maroc, fasc. I. Service géologique, Notes et Mémoires, no 100, pp. 75-195. Casablanca. Choubert, G. et al. (1970): Carte Géologique de l'Anti-Atlas central et de la zone synclinale de Ouarzazate. Feuilles de Ouarzazate, Alougoum et Telouet Sud, ech. 1:200 000. Notes et Mémoires du Service Géologique du Maroc, 138. Gosh, S.K. and Ramberg, H. (1968): Buckling experiments of intersecting fold patterns. Tectonophysics, 5(2): 89-105. Le Blanc, M. (1976): Proterozoic oceanic crust at Bou Azzer. Nature, 261: 34-35.

Health risk assessment of heavy metal variability in sachet water sold in Ado-Odo Ota, South-Western Nigeria.

PubMed

Emenike, PraiseGod Chidozie; Tenebe, Theophilus Imokhai; Omeje, Maxwell; Osinubi, Damilare Samuel

2017-08-31

The sales of sachet water (SW), also known as "pure water" (PW), in Nigeria is a lucrative business. It serves many people, especially low-income earners, by providing a more affordable access to safe drinking water when compared with table water. However, some of the producers of SW do not effectively treat raw water before packaging them for sale. This study investigates the presence and concentrations of heavy metals, such as chromium (Cr), iron (Fe), manganese (Mn), copper (Cu), aluminum (Al), and zinc (Zn) in some samples of SW sold within Ota, Ogun State, Nigeria. Samples of SW from nine different producers were purchased for four consecutive weeks and analyzed to determine the concentrations of these heavy metals in them. Furthermore, health risk indicators, such as chronic daily intake (CDI) and health risk indices (HRI) for children and adults, were calculated separately. The metal concentrations were compared with allowable limits set by the World Health Organization (WHO), Nigerian Industrial Standard (NIS), and the United States Environmental Protection Agency (US EPA). High concentrations of Cr, Fe, and Al were found in all the nine samples and exceeded the maximum allowable limits (MAL) of all the standards considered. However, the concentrations of Zn, Mn, and Cu were within permissible limits. The HRIs of heavy metals were in the order of Cu > Fe > Zn > Mn > Al > Cr, but since the standard limits set for some metals were exceeded, proper and effective treatment is required to safeguard the health of consumers.

Hybrid Exploration Agent Platform and Sensor Web System

NASA Technical Reports Server (NTRS)

Stoffel, A. William; VanSteenberg, Michael E.

2004-01-01

A sensor web to collect the scientific data needed to further exploration is a major and efficient asset to any exploration effort. This is true not only for lunar and planetary environments, but also for interplanetary and liquid environments. Such a system would also have myriad direct commercial spin-off applications. The Hybrid Exploration Agent Platform and Sensor Web or HEAP-SW like the ANTS concept is a Sensor Web concept. The HEAP-SW is conceptually and practically a very different system. HEAP-SW is applicable to any environment and a huge range of exploration tasks. It is a very robust, low cost, high return, solution to a complex problem. All of the technology for initial development and implementation is currently available. The HEAP Sensor Web or HEAP-SW consists of three major parts, The Hybrid Exploration Agent Platforms or HEAP, the Sensor Web or SW and the immobile Data collection and Uplink units or DU. The HEAP-SW as a whole will refer to any group of mobile agents or robots where each robot is a mobile data collection unit that spends most of its time acting in concert with all other robots, DUs in the web, and the HEAP-SWs overall Command and Control (CC) system. Each DU and robot is, however, capable of acting independently. The three parts of the HEAP-SW system are discussed in this paper. The Goals of the HEAP-SW system are: 1) To maximize the amount of exploration enhancing science data collected; 2) To minimize data loss due to system malfunctions; 3) To minimize or, possibly, eliminate the risk of total system failure; 4) To minimize the size, weight, and power requirements of each HEAP robot; 5) To minimize HEAP-SW system costs. The rest of this paper discusses how these goals are attained.

The use of feasibility studies for stepped-wedge cluster randomised trials: protocol for a review of impact and scope.

PubMed

Kristunas, Caroline A; Hemming, Karla; Eborall, Helen C; Gray, Laura J

2017-08-01

The stepped-wedge cluster randomised trial (SW-CRT) is a complex design, for which many decisions about key design parameters must be made during the planning. These include the number of steps and the duration of time needed to embed the intervention. Feasibility studies are likely to be useful for informing these decisions and increasing the likelihood of the main trial's success. However, the number of feasibility studies being conducted for SW-CRTs is currently unknown. This review aims to establish the number of feasibility studies being conducted for SW-CRTs and determine which feasibility issues are commonly investigated. Fully published feasibility studies for SW-CRTs will be identified, according to predefined inclusion criteria, from searches conducted in Ovid MEDLINE, Scopus, Embase and PsycINFO. To also identify and gain information on unpublished feasibility studies the following will be contacted: authors of published SW-CRTs (identified from the most recent systematic reviews); contacts for registered SW-CRTs (identified from clinical trials registries); lead statisticians of UK registered clinical trials units and researchers known to work in the area of SW-CRTs.Data extraction will be conducted independently by two reviewers. For the fully published feasibility studies, data will be extracted on the study characteristics, the rationale for the study, the process for determining progression to a main trial, how the study informed the main trial and whether the main trial went ahead. The researchers involved in the unpublished feasibility studies will be contacted to elicit the same information.A narrative synthesis will be conducted and provided alongside a descriptive analysis of the study characteristics. This review does not require ethical approval, as no individual patient data will be used. The results of this review will be published in an open-access peer-reviewed journal. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Continual Reintroduction of Human Pandemic H1N1 Influenza A Viruses into Swine in the United States, 2009 to 2014

PubMed Central

Stratton, Jered; Killian, Mary Lea; Janas-Martindale, Alicia; Vincent, Amy L.

2015-01-01

ABSTRACT The diversity of influenza A viruses in swine (swIAVs) presents an important pandemic threat. Knowledge of the human-swine interface is particularly important for understanding how viruses with pandemic potential evolve in swine hosts. Through phylogenetic analysis of contemporary swIAVs in the United States, we demonstrate that human-to-swine transmission of pandemic H1N1 (pH1N1) viruses has occurred continuously in the years following the 2009 H1N1 pandemic and has been an important contributor to the genetic diversity of U.S. swIAVs. Although pandemic H1 and N1 segments had been largely removed from the U.S. swine population by 2013 via reassortment with other swIAVs, these antigens reemerged following multiple human-to-swine transmission events during the 2013-2014 seasonal epidemic. These findings indicate that the six internal gene segments from pH1N1 viruses are likely to be sustained long term in the U.S. swine population, with periodic reemergence of pandemic hemagglutinin (HA) and neuraminidase (NA) segments in association with seasonal pH1N1 epidemics in humans. Vaccinating U.S. swine workers may reduce infection of both humans and swine and in turn limit the role of humans as sources of influenza virus diversity in pigs. IMPORTANCE Swine are important hosts in the evolution of influenza A viruses with pandemic potential. Here, we analyze influenza virus sequence data generated by the U.S. Department of Agriculture's national surveillance system to identify the central role of humans in the reemergence of pandemic H1N1 (pH1N1) influenza viruses in U.S. swine herds in 2014. These findings emphasize the important role of humans as continuous sources of influenza virus diversity in swine and indicate that influenza viruses with pandemic HA and NA segments are likely to continue to reemerge in U.S. swine in association with seasonal pH1N1 epidemics in humans. PMID:25833052

Continual Reintroduction of Human Pandemic H1N1 Influenza A Viruses into Swine in the United States, 2009 to 2014.

PubMed

Nelson, Martha I; Stratton, Jered; Killian, Mary Lea; Janas-Martindale, Alicia; Vincent, Amy L

2015-06-01

The diversity of influenza A viruses in swine (swIAVs) presents an important pandemic threat. Knowledge of the human-swine interface is particularly important for understanding how viruses with pandemic potential evolve in swine hosts. Through phylogenetic analysis of contemporary swIAVs in the United States, we demonstrate that human-to-swine transmission of pandemic H1N1 (pH1N1) viruses has occurred continuously in the years following the 2009 H1N1 pandemic and has been an important contributor to the genetic diversity of U.S. swIAVs. Although pandemic H1 and N1 segments had been largely removed from the U.S. swine population by 2013 via reassortment with other swIAVs, these antigens reemerged following multiple human-to-swine transmission events during the 2013-2014 seasonal epidemic. These findings indicate that the six internal gene segments from pH1N1 viruses are likely to be sustained long term in the U.S. swine population, with periodic reemergence of pandemic hemagglutinin (HA) and neuraminidase (NA) segments in association with seasonal pH1N1 epidemics in humans. Vaccinating U.S. swine workers may reduce infection of both humans and swine and in turn limit the role of humans as sources of influenza virus diversity in pigs. Swine are important hosts in the evolution of influenza A viruses with pandemic potential. Here, we analyze influenza virus sequence data generated by the U.S. Department of Agriculture's national surveillance system to identify the central role of humans in the reemergence of pandemic H1N1 (pH1N1) influenza viruses in U.S. swine herds in 2014. These findings emphasize the important role of humans as continuous sources of influenza virus diversity in swine and indicate that influenza viruses with pandemic HA and NA segments are likely to continue to reemerge in U.S. swine in association with seasonal pH1N1 epidemics in humans. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Prior infection of pigs with a recent human H3N2 influenza virus confers minimal cross-protection against a European swine H3N2 virus.

PubMed

Qiu, Yu; van der Meulen, Karen; Van Reeth, Kristien

2013-11-01

H3N2 influenza viruses circulating in humans and European pigs originate from the pandemic A/Hong Kong/68 virus. Because of slower antigenic drift in swine, the antigenic divergence between swine and human viruses has been increasing. It remains unknown to what extent this results in a reduced cross-protection between recent human and swine H3N2 influenza viruses. We examined whether prior infection of pigs with an old [A/Victoria/3/75 (A/Vic/75)] or a more recent [A/Wisconsin/67/05 (A/Wis/05)] human H3N2 virus protected against a European swine H3N2 virus [sw/Gent/172/08 (sw/Gent/08)]. Genetic and antigenic relationships between sw/Gent/08 and a selection of human H3N2 viruses were also assessed. After challenge with sw/Gent/08, all challenge controls had high virus titers in the entire respiratory tract at 3 days post-challenge and nasal virus excretion for 5-6 days. Prior infection with sw/Gent/08 or A/Vic/75 offered complete virological protection against challenge. Pigs previously inoculated with A/Wis/05 showed similar virus titers in the respiratory tract as challenge controls, but the mean duration of nasal shedding was 1·3 days shorter. Unlike sw/Gent/08- and A/Vic/75-inoculated pigs, A/Wis/05-inoculated pigs lacked cross-reactive neutralizing antibodies against sw/Gent/08 before challenge, but they showed a more rapid antibody response to sw/Gent/08 than challenge controls after challenge. Cross-protection and serological responses correlated with genetic and antigenic differences. Infection immunity to a recent human H3N2 virus confers minimal cross-protection against a European swine H3N2 virus. We discuss our findings with regard to the recent zoonotic infections of humans in the United States with a swine-origin H3N2 variant virus. © 2013 John Wiley & Sons Ltd.

A Student Experiment Method for Learning the Basics of Embedded Software Technologies Including Hardware/Software Co-design

NASA Astrophysics Data System (ADS)

Kambe, Hidetoshi; Mitsui, Hiroyasu; Endo, Satoshi; Koizumi, Hisao

The applications of embedded system technologies have spread widely in various products, such as home appliances, cellular phones, automobiles, industrial machines and so on. Due to intensified competition, embedded software has expanded its role in realizing sophisticated functions, and new development methods like a hardware/software (HW/SW) co-design for uniting HW and SW development have been researched. The shortfall of embedded SW engineers was estimated to be approximately 99,000 in the year 2006, in Japan. Embedded SW engineers should understand HW technologies and system architecture design as well as SW technologies. However, a few universities offer this kind of education systematically. We propose a student experiment method for learning the basics of embedded system development, which includes a set of experiments for developing embedded SW, developing embedded HW and experiencing HW/SW co-design. The co-design experiment helps students learn about the basics of embedded system architecture design and the flow of designing actual HW and SW modules. We developed these experiments and evaluated them.

77 FR 47089 - Land Acquisitions; United Keetoowah Band of Cherokee Indians of Oklahoma

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-07

... July 30, 2012. FOR FURTHER INFORMATION CONTACT: Paula L. Hart, Director, Office of Indian Gaming... the S/2 NE/4 SE/4 SW/4 and part of the N/2 SE/4 SE/4 SW/4 of Section 4, T-16-N, R-22- E, Cherokee... point 175.00 feet South of the North boundary of said N/2 SE/4 SE/4 SW/4; thence S 89[deg]49' E, 384.32...

Antigenic variation of the human influenza A (H3N2) virus during the 2014-2015 winter season.

PubMed

Hua, Sha; Li, XiYan; Liu, Mi; Cheng, YanHui; Peng, YouSong; Huang, WeiJuan; Tan, MinJu; Wei, HeJiang; Guo, JunFeng; Wang, DaYan; Wu, AiPing; Shu, YueLong; Jiang, TaiJiao

2015-09-01

The human influenza A (H3N2) virus dominated the 2014-2015 winter season in many countries and caused massive morbidity and mortality because of its antigenic variation. So far, very little is known about the antigenic patterns of the recent H3N2 virus. By systematically mapping the antigenic relationships of H3N2 strains isolated since 2010, we discovered that two groups with obvious antigenic divergence, named SW13 (A/Switzerland/9715293/2013-like strains) and HK14 (A/Hong Kong/5738/2014-like strains), co-circulated during the 2014-2015 winter season. HK14 group co-circulated with SW13 in Europe and the United States during this season, while there were few strains of HK14 in mainland China, where SW13 has dominated since 2012. Furthermore, we found that substitutions near the receptor-binding site on hemagglutinin played an important role in the antigenic variation of both the groups. These findings provide a comprehensive understanding of the recent antigenic evolution of H3N2 virus and will aid in the selection of vaccine strains.

Environmental Assessment for Ecosystem Restoration Masterplan Implementation at MacDill Air Force Base, Florida

DTIC Science & Technology

2013-05-01

PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) AMEC...Environment & Infrastructure, Inc,404 SW 140th Terrace,Newberry,FL,32669 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY... perform a coastal zone consistency evaluation. The State of Florida determined that the Proposed Action is consistent with the Florida CMP. FINDING

Molecular Epidemiology and Evolution of West Nile Virus in North America

PubMed Central

Mann, Brian R.; McMullen, Allison R.; Swetnam, Daniele M.; Barrett, Alan D. T.

2013-01-01

West Nile virus (WNV) was introduced to New York in 1999 and rapidly spread throughout North America and into parts of Central and South America. Displacement of the original New York (NY99) genotype by the North America/West Nile 2002 (NA/WN02) genotype occurred in 2002 with subsequent identification of a novel genotype in 2003 in isolates collected from the southwestern Unites States region (SW/WN03 genotype). Both genotypes co-circulate to date. Subsequent WNV surveillance studies have confirmed additional genotypes in the United States that have become extinct due to lack of a selective advantage or stochastic effect; however, the dynamic emergence, displacement, and extinction of multiple WNV genotypes in the US from 1999–2012 indicates the continued evolution of WNV in North America. PMID:24135819

Unravelling the role of the SW Sextantis stars in the evolution of cataclysmic variables

NASA Astrophysics Data System (ADS)

Torres, Manuel; Steeghs, Danny; Gaensicke, Boris; Marsh, Tom; Rodriguez-Gil, Pablo; Schmidtobreick, Linda; Long, Knox; Schreiber, Matthias

2007-08-01

SW Sextantis stars are a relatively large group of cataclysmic variables (CVs) whose properties contradict all predictions made by the current CV evolution theories. Very little is known about the properties of their accreting white dwarfs and their donor stars, as the stellar components are usually outshone by an extremely bright accretion flow. Consequently, a proper assesment of their evolutionary state is illusionary. We are monitoring the brightness of a number of SW Sex stars and request here Gemini/GMOS-N ToO time to obtain orbital phase-resolved spectroscopy if one of them enters a low state, since this is the only opportunity for studying the stellar components individually. These data will be used to accurately measure the mass ratio of the system which, combined with the orbital inclination derived from modelling of either the disc eclipses in the high state or the ellipsoidal modulation in the low state, will eventually provide the first detailed system parameters for any SW Sex star.

Unravelling the role of the SW Sextantis stars in the evolution of cataclysmic variables

NASA Astrophysics Data System (ADS)

Torres, Manuel

2007-02-01

SW Sextantis stars are a relatively large group of cataclysmic variables (CVs) whose properties contradict all predictions made by the current CV evolution theories. Very little is known about the properties of their accreting white dwarfs and their donor stars, as the stellar components are usually outshone by an extremely bright accretion flow. Consequently, a proper assesment of their evolutionary state is illusionary. We are monitoring the brightness of a number of SW Sex stars and request here Gemini/GMOS-N ToO time to obtain orbital phase-resolved spectroscopy if one of them enters a low state, since this is the only opportunity for studying the stellar components individually. These data will be used to accurately measure the mass ratio of the system which, combined with the orbital inclination derived from modelling of either the disc eclipses in the high state or the ellipsoidal modulation in the low state, will eventually provide the first detailed system parameters for any SW Sex star.

Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer

PubMed Central

Tanner, Julie-Anne; Henderson, Jeffrey A.; Buchwald, Dedra; Howard, Barbara V.; Henderson, Patricia Nez; Tyndale, Rachel F.

2017-01-01

Objectives The Northern Plains (NP) and Southwest (SW) American Indian populations differ in their smoking patterns and lung cancer incidence. We aimed to compare CYP2A6 genetic variation and CYP2A6 enzyme activity (representative of the rate of nicotine metabolism) between the two tribal populations, as these have previously been associated with differences in smoking, quitting, and lung cancer risk. Methods American Indians (N=636) were recruited from two different tribal populations (NP in South Dakota, SW in Arizona) as part of a study conducted as part of the Collaborative to Improve Native Cancer Outcomes P50 project. A questionnaire assessed smoking-related traits and demographics. Participants were genotyped for CYP2A6 genetic variants *1B, *2, *4, *7, *9, *12, *17, and *35. Plasma and/or saliva samples were used to measure nicotine’s metabolites cotinine and 3′-hydroxycotinine and determine CYP2A6 activity (3′-hydroxcotinine/cotinine, i.e. the nicotine metabolite ratio, NMR). Results The overall frequency of genetically reduced nicotine metabolizers, those with CYP2A6 decrease- or loss-of-function alleles, was lower in the NP compared to the SW (P=0.0006). CYP2A6 genotype was associated with NMR in both tribal groups (NP P<0.001, SW P=0.04). Notably, the rate of nicotine metabolism was higher in NP compared to SW smokers (P=0.03), and in comparison to other ethnic groups in the United States. Of the variables studied, CYP2A6 genotype was the only variable to significantly independently influence NMR among smokers in both tribal populations (NP P<0.001, SW P=0.05). Conclusions Unique CYP2A6 allelic patterns and rates of nicotine metabolism among these American Indian populations suggest different risks for smoking and tobacco-related disease. PMID:28181923

Effects of hexazinone and atrazine on the physiology and endocrinology of smolt development in Atlantic salmon

USGS Publications Warehouse

Nieves-Puigdoller, K.; Bjornsson, Bjorn Thrandur; McCormick, S.D.

2007-01-01

Exposure to hexazinone (HEX) and atrazine (ATZ), highly mobile and widely used herbicides along rivers in the United States, is potentially harmful to Atlantic salmon, which have been listed as an endangered species. To determine the effects of these contaminants on smolt development, juvenile Atlantic salmon were exposed under flow-through conditions to 100 ??g l-1 HEX, 10 and 100 ??g l-1 ATZ in fresh water (FW) for 21 days at 10 ??C beginning in mid-April. Twelve fish per treatment were sampled in FW, following a 24 h seawater (SW) challenge and after growth for 3 months in SW. Exposure to 100 ??g l-1 HEX or 10 ??g l-1 ATZ caused no mortalities of smolts in FW or after SW challenge, while 9% of the fish exposed to 100 ??g l-1 ATZ died during exposure. Fish exposed to 100 ??g l-1 ATZ reduced feeding after 10 days of exposure and had an impaired growth rate in FW and during the first month in SW; compensatory growth occurred in the second and third month in SW. HEX and ATZ at 10 ??g l-1 exposure had no effect on plasma levels of cortisol, growth hormone (GH), insulin growth factor I (IGF-I), thyroxine (T4) and plasma 3,5,3???-triiodo-l-thyronine (T3), Cl-, Mg2+, Na+, Ca2+ in FW or after SW challenge. FW smolts exposed to 100 ??g l-1 ATZ had decreased plasma Cl-, Mg2+, Na+ and Ca2+ ions and increased cortisol. No effect on plasma levels of GH, IGF-I, T4 or T3 was found in FW smolts exposed to 100 ??g l-1 ATZ. Following SW challenge, fish previously exposed to 100 ??g l-1 ATZ had significant increases in hematocrit, plasma cortisol, Cl-, Mg2+, Na+, Ca2+ and a decrease in T4 and T3. It is concluded that under the conditions imposed in this study, HEX does not affect salinity tolerance of Atlantic salmon smolts, while ATZ causes ionoregulatory, growth and endocrine disturbance. ?? 2007 Elsevier B.V. All rights reserved.

Accelerating Smith-Waterman Alignment for Protein Database Search Using Frequency Distance Filtration Scheme Based on CPU-GPU Collaborative System.

PubMed

Liu, Yu; Hong, Yang; Lin, Chun-Yuan; Hung, Che-Lun

2015-01-01

The Smith-Waterman (SW) algorithm has been widely utilized for searching biological sequence databases in bioinformatics. Recently, several works have adopted the graphic card with Graphic Processing Units (GPUs) and their associated CUDA model to enhance the performance of SW computations. However, these works mainly focused on the protein database search by using the intertask parallelization technique, and only using the GPU capability to do the SW computations one by one. Hence, in this paper, we will propose an efficient SW alignment method, called CUDA-SWfr, for the protein database search by using the intratask parallelization technique based on a CPU-GPU collaborative system. Before doing the SW computations on GPU, a procedure is applied on CPU by using the frequency distance filtration scheme (FDFS) to eliminate the unnecessary alignments. The experimental results indicate that CUDA-SWfr runs 9.6 times and 96 times faster than the CPU-based SW method without and with FDFS, respectively.

76 FR 76181 - Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Issuance of General...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-06

..., 500 E Street SW., Washington, DC 20436, telephone (202) 205-3065. Copies of non-confidential documents..., 500 E Street SW., Washington, DC 20436, telephone (202) 205-2000. General information concerning the...''); Paradigm Marketing Consortium, Inc. of Syosset, New York; United Sourcing Network Corp. of Syosset, New...

Participant’s Manual to Accompany the Yugoslav Dilemma (A Computer Simulation)

DTIC Science & Technology

1984-02-01

INOV 65IS OBSOLETE UCASFE S/W 0102.0P.01461101 UCASFE SECURITY CLASSIFICATION OF THIS PAGE (Vh.n Do#& 800ae.) % % P . . ... J4 , . .. . S. FOREWORD... Poland caused Europeans to think carefully about the tendency to rely heavily on the benefits of detente as a basis for foreign policy. The Soviet...contracts were signed with Hungary and Poland for the supply of industrial plants. A Defense Cooperation Agreement was signed with the United States. It

Structural Basis for Bc12-Regulated Mitochondrion-Dependent Apoptosis

DTIC Science & Technology

2005-04-01

groups , double-resonance (’H/15N or 1H/ 31P) probes had square r.f. which have a considerably narrower ’IN chemical shift coils wrapped directly around...bilayers, which provides no res- B E H olution [Fig. 5(D)]. The peak near 35 ppm results from the amino groups of the lysine side-chains and the N...tissue-specific and physiological state-specific sub- 21. Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET. Proc. units of the Na+, K+-ATPase. The

Evaluation of Lime and Persulfate Treatment for Mixed Contaminant Soil from Plum Brook Ordnance Works (Sandusky, OH)

DTIC Science & Technology

2007-09-01

sulfuric acid , and analyzed according to USEPA Method 8082 (1996) using a Hewlett Packard Series II 5890 Gas Chromatograph equipped with dual electron... sulfuric acid to reduce the slurry pH to approximately 4, and • 30 percent H2O2 to create a 100-mg/L final aqueous concentration. Cobble treatment...Wastes: Physical/Chemical Methods (USEPA SW 846). 1996. Method 3665A. Sulfuric acid /permanganate cleanup. Washington, DC. United States

Selecting Effective Fluorescent Lamp and Ballast for Retrofit in the Continental United States

DTIC Science & Technology

1993-08-01

SPONSORINGIMONITORING U.S. Army Engineering and Housing Support Center (USAEHSC) AGENCY REPORT NUMBER ATTN: CEHSC-FB-S Bldg. 358 Fort Belvoir, VA 22060...SW 239-18 298-102 FOREWORD This work was done for the U.S. Army Engineering and Housing Support Center (USAEHSC), Fort Belvoir, VA, under Military...Chief of Enrpuen ATTN SMCRI-TI. CEWES 49180 LS C-. i Pninst Office 20601 ATTN. CEHEC-IrE-It ) 2 Walerviaf Awseal 121IN ATrN Ldwwry ATTN Rac SeAc/qosue

Unravelling the role of SW Sextantis stars in the evolution of cataclysmic variables

NASA Astrophysics Data System (ADS)

Araujo-Betancor, Sofia; Gansicke, Boris; Long, Knox; Rodriguez-Gil, Pablo

2005-08-01

SW Sextantis stars are a relatively large group of cataclysmic variables whose properties contradict all predictions made by the current CV evolution theories. Very little is known about the properties of their accreting white dwarfs and their donor stars, as the stellar components are usually outshone by an extremely bright accretion flow. Consequently, a proper assessment of their evolutionary state is illusionary. There is one particular behavior of the SW Sex stars that can allow us to overcome this problem: SW Sex stars exhibit low states during which accretion onto the white dwarf decreases or shuts off completely. Only during this rare occasions we can directly observe the white dwarf and the donor star in these systems, and measurements of the white dwarf temperature, spectral type of the donor, mass and distance to the system can be carried out. With this aim in mind, we have set up a long-term monitoring of a group of five SW Sex stars using the 1.3 m telescope at CTIO. Here we propose to activate follow-up TOOs to obtain optical spectra of the low states to accurately determine the fundamental properties of these systems.

Unravelling the Role of the SW Sextantis Stars in the Evolution of Cataclysmic Variables

NASA Astrophysics Data System (ADS)

Torres, Manuel; Steeghs, D.; Rodriguez-Gil, P.; Gansicke, B.; Marsh Warwick, T. R.; Araujo-Betancor, S.; Long, K.

2006-08-01

SW Sextantis stars are a relatively large group of cataclysmic variables whose properties contradict all predictions made by the current CV evolution theories. Very little is known about the properties of their accreting white dwarfs and their donor stars, as the stellar components are usually outshone by an extremely bright accretion flow. Consequently, a proper assesment of their evolutionary state is illusionary. We are monitoring the brightness of 33 SW Sex stars, and request here Gemini/GMOS-N time to obtain orbital phase-resolved spectroscopy if one of them enters a low state. These data will be used to accurately measure the mass ratio, white dwarf temperature, and distance of the system, eventually providing the first detailed system parameters for any SW Sex star.

75 FR 76485 - Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice of Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

... General Counsel, U.S. International Trade Commission, 500 E Street, SW., Washington, DC 20436, telephone... Office of the Secretary, U.S. International Trade Commission, 500 E Street, SW., Washington, DC 20436...; United Sourcing Network Corp. of Syosset, New York; New Choice (H.K.) Ltd. of Shatin, Hong Kong; and Vida...

75 FR 51842 - In the Matter of Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... Commission, 500 E Street, SW., Washington, DC 20436, telephone (202) 708-2301. Copies of non- confidential... Commission, 500 E Street, SW., Washington, DC 20436, telephone (202) 205-2000. General information concerning... Marketing Consortium, Inc. of Syosset, New York; United Sourcing Network Corp. of Syosset, New York; New...

TESTING TREE-CLASSIFIER VARIANTS AND ALTERNATE MODELING METHODOLOGIES IN THE EAST GREAT BASIN MAPPING UNIT OF THE SOUTHWEST REGIONAL GAP ANALYSIS PROJECT (SW REGAP)

EPA Science Inventory

We tested two methods for dataset generation and model construction, and three tree-classifier variants to identify the most parsimonious and thematically accurate mapping methodology for the SW ReGAP project. Competing methodologies were tested in the East Great Basin mapping un...

Temporal evolution of solar wind ion composition and their source coronal holes during the declining phase of cycle 23. I. Low-latitude extension of polar coronal holes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ko, Yuan-Kuen; Wang, Yi-Ming; Muglach, Karin

2014-06-01

We analyzed 27 solar wind (SW) intervals during the declining phase of cycle 23, whose source coronal holes (CHs) can be unambiguously identified and are associated with one of the polar CHs. We found that the SW ions have a temporal trend of decreasing ionization state, and such a trend is different between the slow and fast SW. The photospheric magnetic field, both inside and at the outside boundary of the CH, also exhibits a trend of decrease with time. However, EUV line emissions from different layers of the atmosphere exhibit different temporal trends. The coronal emission inside the CHmore » generally increases toward the CH boundary as the underlying field increases in strength and becomes less unipolar. In contrast, this relationship is not seen in the coronal emission averaged over the entire CH. For C and O SW ions that freeze-in at lower altitude, stronger correlation between their ionization states and field strength (both signed and unsigned) appears in the slow SW, while for Fe ions that freeze-in at higher altitude, stronger correlation appears in the fast SW. Such correlations are seen both inside the CH and at its boundary region. On the other hand, the coronal electron temperature correlates well with the SW ion composition only in the boundary region. Our analyses, although not able to determine the likely footpoint locations of the SW of different speeds, raise many outstanding questions for how the SW is heated and accelerated in response to the long-term evolution of the solar magnetic field.« less

A new analysis of archival images of comet 29P/Schwassmann-Wachmann 1 to constrain the rotation state of and active regions on its nucleus

NASA Astrophysics Data System (ADS)

Schambeau, C.; Fernández, Y.; Samarasinha, N.; Mueller, B.; Woodney, L.; Lisse, C.; Kelley, M.; Meech, K.

2014-07-01

Introduction: 29P/Schwassmann-Wachmann 1 (SW1) is a unique comet (and Centaur) with an almost circular orbit just outside the orbit of Jupiter. This orbit results in SW1 receiving a nearly constant insolation, thus giving a simpler environment in which to study thermal properties and behaviors of this comet's nucleus. Such knowledge is crucial for improving our understanding of coma morphology, nuclear thermal evolution, and nuclear structure. To this end, our overarching goal is to develop a thermophysical model of SW1's nucleus that makes use of realistic physical and structural properties as inputs. This model will help to explain the highly variable gas- and dust-production rates of this comet; SW1 is well known for its frequent but stochastic outbursts of mass loss [1,2,3]. Here we will report new constraints on the effective radius, beaming parameter, spin state, and location of active regions on the nucleus of SW1. Results: The analysis completed so far consists of a re-analysis of Spitzer Space Telescope thermal-IR images of SW1 from UT 2003 November 21 and 24, when SW1 was observed outside of outburst. The images are from Spitzer's IRAC 5.8-μm and 8.0-μm bands and MIPS 24.0-μm and 70-μm bands. This analysis is similar to that of Stansberry et al. [4, 5], but with data products generated from the latest Spitzer pipeline. Also, analysis of the 5.8-μm image had not been reported before. Coma removal techniques (e.g., Fernández et al. [6]) were applied to each image letting us measure the nuclear point-source contribution to each image. The measured flux densities for each band were fit with a Near Earth Asteroid Thermal Model (NEATM, [7]) and resulted in values for the effective radius of SW1's nucleus, constraints on the thermal inertia, and an IR beaming-parameter value. Current efforts have shifted to constraining the spin properties of SW1's nucleus and surface areas of activity through use of an existing Monte Carlo model [8, 9] to reproduce existing images (in our possession) of SW1's dust coma while in and out of outburst. The images analyzed so far consist of R-band (CCD) images of SW1 taken with the Kitt Peak National Observatory 2.1-m telescope on Sept. 25.5, 26.5, 27.5, 28.5, and 29.5 UT in 2008 [10]. SW1 was undergoing an outburst during this time and showed three continuous radial jets of material as well as at least one and possibly two expanding shells, all of which may let us constrain the active areas and the spin properties of the nucleus. By using the nucleus's spin state, location and extent of active areas, and dust-grain velocities as inputs to the model, we will mimic the observed coma morphology. Using this technique, we will present constraints to the nuclear properties of SW1. It is expected that due to the large size of SW1's nucleus measured earlier, any rotational excitation of the nucleus would/should have damped to a principal-axis spin state, simplifying our modeling efforts. The coma modeling will also enable us to examine this assumption.

USDA Southwest Regional Hub for Adaptation to and Mitigation of Climate Change

NASA Astrophysics Data System (ADS)

Rango, A.; Elias, E.; Steele, C. M.; Havstad, K.

2014-12-01

The USDA Southwest (SW) Climate Hub was created in February 2014 to develop risk adaptation and mitigation strategies for coping with climate change effects on agricultural productivity. There are seven regional hubs across the country with three subsidiary hubs. The SW Climate Hub Region is made up of six states: New Mexico, Arizona, Utah, Nevada, California and Hawaii (plus the Trust Territories of the Pacific Islands). The SW Climate Hub has a subsidiary hub located in Davis, California. The Southwest region has high climatic diversity, with the lowest and highest average annual rainfall in the U.S.(6.0 cm in Death Valley, CA and 1168 cm at Mt. Waialeale, HI). There are major deserts in five of the six states, yet most of the states, with exception of Hawaii, depend upon the melting of mountain snowpacks for their surface water supply. Additionally, many of the agricultural areas of the SW Regional Hub depend upon irrigation water to maintain productivity. Scientific climate information developed by the Hub will be used for climate-smart decision making. To do this, the SW Regional Hub will rely upon existing infrastructure of the Cooperative Extension Service at Land-Grant State Universities. Extension service and USDA-NRCS personnel have existing networks to communicate with stakeholders (farmers, ranchers, and forest landowners) through meetings and workshops which have already started in the six states. Outreach through the development of a weather and climate impact modules designed for seventh grade students and their teachers will foster education of future generations of rural land managers. We will be synthesizing and evaluating existing reports, literature and information on regional climate projections, water resources, and agricultural adaptation strategies related to climate in the Southwest. The results will be organized in a spatial format and provided through the SW Hub website (http://swclimatehub.info) and peer-reviewed articles.

Influences of North Atlantic Oscillation (NAO) on warm season temperature and crop yields in the southwestern US

NASA Astrophysics Data System (ADS)

Myoung, B.; Kim, S.; Kim, J.; Kafatos, M.

2013-12-01

Despite advancements in agricultural technology, agricultural productivity remains vulnerable to extreme meteorological conditions. This study has found significant impacts of North Atlantic Oscillation (NAO) on extreme temperatures and in turn on crop yields in the Southwestern United States (SW US) region. Analyses of multi-year data of observed temperatures and simulated maize yields reveal that NAO affects positively the daily temperature maxima and minima in the green-up periods (March-June) and that the response of maize yields to NAO varies according to the climatological mean temperatures. In warmer regions, a combination of above-normal NAO in the planting periods and below-normal NAO in the growing periods is favorable for high maize yields by reducing extremely cold days during the planting periods and extremely hot days in the later periods, respectively. In colder regions, continuously above-normal NAO conditions favor higher yields via above normal thermal conditions. Results in this study suggest that NAO predictions can benefit agricultural planning in SW US.

The Southwest Residential Experiment Station - The first year

NASA Astrophysics Data System (ADS)

Zwibel, H. S.; Schaefer, J. F.

A history and status report on the Southwest Residential Experiment Station (SW RES) aimed at instituting residential applications of prototype residence-like photovoltaic systems is given. The three-acre SW RES site has an average annual insolation of 2375 kwhr/sq m, one of the highest in the United States. The eight prototypes under construction are aimed at suitability for the meteorological, cultural, and economic climates of the southwest, design compatibility with residence design with maintenance for one year after turnkey, and a minimum 100 W preproduction module. Useful information resulting from the program includes the redirection of a 4 kW array reducing costs by a factor of 20, awareness of the interference of Spring winds in handling modules larger than 1 ft x 4 ft, and the fact that white aggregate roofing gravel, south of an optimally tilted array, enhances array performance. In addition, each prototype is instrumented for performance monitoring and is equipped with a residential load simulator capable of dissipating from 0 to 26 kW in 100 watt increments.

Installation Restoration Program. Phase 2. Confirmation/Quantification. Stage 1 for United States Air Force Plant Number 59, Johnson City, New York. Appendices

DTIC Science & Technology

1988-03-01

AFP 59 SW-4 Production Field Blank Water Well Water Hart 004 Water Hart 005 f Hart 007 H.3-13 PRINCETON TESTING LABORATORYI 3v~ zANA -YS--S REDO:’- =I...observations. Enforcing the "buddy system" where appropriate. " Determining and posting locations and routes to medical facili- ties, including...poison control centers; arranging for emergency transportation to medical facilities. " Notifying local public emergency officers, i.e., police and fire

Installation Restoration Program Records Search for Richards-Gebaur Air Force Base, Missouri.

DTIC Science & Technology

1983-03-01

Richards-Gebaur AFB is located on the King anticline, a structural rise favorable for oil and gas production and the oldest gas -producing area in Cass... Oil and Gas Section Chief Don Miller, Ground Water Section Chief 314/364-1752 10. Missouri Department of Natural Resources Kansas City, Missouri Jim...tha uthe United states USMrce sac.. the Ne’lowf Ut of OMVieead this reprt my he rmfau Notsma" I9eb6isuL ?UE service SW~ Partlw Iptbf ll. Yi~taa, T21

Continual re-introduction of human pandemic H1N1 influenza A viruses into US swine, 2009-2014

USDA-ARS?s Scientific Manuscript database

Human-to-swine transmission of pandemic H1N1 influenza viruses (pH1N1) increased the genetic diversity of influenza A viruses in swine (swIAVs) globally and is linked to the emergence of new pandemic threats, including H3N2v variants. Through phylogenetic analysis of contemporary swIAVs in the Unit...

Examining the association between implementation and outcomes : state-wide scale-up of school-wide positive behavior intervention and supports.

PubMed

Pas, Elise T; Bradshaw, Catherine P

2012-10-01

Although there is an established literature supporting the efficacy of a variety of prevention programs, there has been less empirical work on the translation of such research to everyday practice or when scaled-up state-wide. There is a considerable need for more research on factors that enhance implementation of programs and optimize outcomes, particularly in school settings. The current paper examines how the implementation fidelity of an increasingly popular and widely disseminated prevention model called, School-wide Positive Behavioral Interventions and Supports (SW-PBIS), relates to student outcomes within the context of a state-wide scale-up effort. Data come from a scale-up effort of SW-PBIS in Maryland; the sample included 421 elementary and middle schools trained in SW-PBIS. SW-PBIS fidelity, as measured by one of three fidelity measures, was found to be associated with higher math achievement, higher reading achievement, and lower truancy. School contextual factors were related to implementation levels and outcomes. Implications for scale-up efforts of behavioral and mental health interventions and measurement considerations are discussed.

SW Sextantis in an excited, low state

NASA Astrophysics Data System (ADS)

Groot, P. J.; Rutten, R. G. M.; van Paradijs, J.

2001-03-01

We present low-resolution spectrophotometric optical observations of the eclipsing nova-like cataclysmic variable SW Sex, the prototype of the SW Sex stars. We observed the system when it was in an unusual low state. The spectrum is characterized by the presence of strong Heii and Civ emission lines as well as the normal single peaked Balmer emission lines. The radial temperature profile of the disk follows the expected T~ R-3/4 only in the outer parts and flattens off inside 0.5 times the white dwarf Roche lobe radius. The single peaked emission lines originate in a region above the plane of the disk, at the position of the hot spot.

Sampling and analyses plan for tank 103 at the 219-S waste handling facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOWLER, K.D.

1999-06-23

This document describes the sampling and analysis activities associated with taking a Resource Conservation and Recovery Act (RCRA) protocol sample of the waste from Tank 103 at the 21 9-S Waste Handling Facility treatment storage, andlor disposal (TSD) unit at the 2224 Laboratory complex. This sampling and analyses is required based on negotiations between the State of Washington Department of Ecology (Ecology) and the Department of Energy, Richland Operations, (RL) in letters concerning the TPA Change Form M-32-98-01. In a letter from George H. Sanders, RL to Moses N. Jaraysi, Ecology, dated January 28,1999, it was noted that ''Prior tomore » the Tank 103 waste inventory transfer, a RCRA protocol sample of the waste will be obtained and tested for the constituents contained on the Part A, Form 3 Permit Application for the 219-S Waste Handling Facility.'' In the April 2, 1999 letter, from Brenda L. Becher-Khaleel, Ecology to James, E. Rasmussen, RL, and William O. Adair, FDH, Ecology states that the purpose of these analyses is to provide information and justification for leaving Tank 103 in an isolated condition in the 2194 TSD unit until facility closure. The data may also be used at some future date in making decisions regarding closure methodology for Tank 103. Ecology also notes that As Low As Reasonably Achievable (ALARA) concerns may force deviations from some SW-846 protocol. Every effort will be made to accommodate requirements as specified. Deviations from SW-846 will be documented in accordance with HASQARD.« less

Control of scroll wave turbulence in a three-dimensional reaction-diffusion system with gradient.

PubMed

Qiao, Chun; Wu, Yabi; Lu, Xiaochuan; Wang, Chunyan; Ouyang, Qi; Wang, Hongli

2008-06-01

In this paper, we summarize our recent experimental and theoretical works on observation and control of scroll wave (SW) turbulence. The experiments were conducted in a three-dimensional Belousov-Zhabotinsky reaction-diffusion system with chemical concentration gradients in one dimension. A spatially homogeneous external forcing was used in the experiments as a control; it was realized by illuminating white light on the light sensitive reaction medium. We observed that, in the oscillatory regime of the system, SW can appear automatically in the gradient system, which will be led to spatiotemporal chaos under certain conditions. A suitable periodic forcing may stabilize inherent turbulence of SW. The mechanism of the transition to SW turbulence is due to the phase twist of SW in the presence of chemical gradients, while modulating the phase twist with a proper periodic forcing can delay this transition. Using the FitzHugh-Nagumo model with an external periodic forcing, we confirmed the control mechanism with numerical simulation. Moreover, we also show in the simulation that adding temporal external noise to the system may have the same control effect. During this process, we observed a new state called "intermittent turbulence," which may undergo a transition into a new type of SW collapse when the noise intensity is further increased. The intermittent state and the collapse could be explained by a random process.

Nickel elution properties of contemporary interatrial shunt closure devices.

PubMed

Verma, Divya Ratan; Khan, Muhammad F; Tandar, Anwar; Rajasekaran, Namakkal S; Neuharth, Renée; Patel, Amit N; Muhlestein, Joseph B; Badger, Rodney S

2015-02-01

We sought to compare nickel elution properties of contemporary interatrial shunt closure devices in vitro. There are two United States Food and Drug Administration (FDA)-approved devices for percutaneous closure of secundum atrial septal defect: the Amplatzer septal occluder (ASO; St Jude Medical Corporation) and Gore Helex septal occluder (HSO; W.L. Gore & Associates). The new Gore septal occluder (GSO) device is in clinical trials. These are also used off-label for patent foramen ovale closure in highly selected patients. These devices have high nickel content. Nickel allergy is the most common reason for surgical device explantation. Nickel elution properties of contemporary devices remain unknown. We compared nickel elution properties of 4 devices - ASO, GSO, HSO, and sternal wire (SW) - while Dulbecco's phosphate-buffered saline (DPBS) served as control. Three samples of each device were submerged in DPBS. Nickel content was measured at 14 intervals over 90 days. Nickel elution at 24 hours, compared to control (0.005 ± 0.0 mg/L), was significantly higher for ASO (2.98 ± 1.65 mg/L; P=.04) and SW (0.03 ± 0.014 mg/L; P=.03). Nickel levels at 90 days, compared to control (0.005 ± 0.0 mg/L) and adjusting for multiple comparisons, were significantly higher for ASO (19.80 ± 2.30 mg/L; P=.01) and similar for HSO (P=.34), GSO (P=.34), and SW (P=.34). ASO had significantly higher nickel elution compared to HSO, GSO, and SW (P=.01). There is substantial variability in nickel elution; devices with less exposed nickel (HSO and GSO) have minimal elution. The safety of low nickel elution devices in patients with nickel allergy needs to be evaluated in prospective trials.

Cover sequence stratigraphy and structure: Salem Church basement culmination, Georgia Blue Ridge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, L.; Tull, J.F.

The Salem Church anticline SW of Jasper, Georgia in the western Blue Ridge is roughly an oval shaped structural dome with its long axis trending NE-SW. The anticline is cored by the Grenville age Corbin Gneiss which represents allochthonous North American basement. In debate for decades has been the age and origin of several kilometers of poly-deformed cover sequence rocks which were metamorphosed to greenschist facies and were probably transported over a long distance inland after their deposition. The stratigraphy of the cover sequence exhibits rapid lithofacies changes. At most localities, the basement is overlain by a 500--600 m thickmore » coarse clastic unit sourced from the basement rocks, composed mainly of metaconglomerate, metasandstone and metadiamictite. A thin unit less than 20 m thick of sericite phyllite occurs between the basement and the coarse clastic unit along the SE limb of the anticline but pinches out to the MW. A relatively sharp stratigraphic contact occurs between quartzite unit and overlying dark colored metagreywackes and metadiamictites containing distinctive cobbles and boulders of granitic and gneissic basement rocks up to 1 meter in length. This unit is about 100 m thick in the SW but thins rapidly towards the NE. It grades up into a geographically widespread graphitic phyllite which encircles most of the anticline. Unlike the cover sequence above the corbin basement west of Waleska, Georgia, no carbonate is found in this area.« less

The primary role of the SW Sextantis stars in the evolution of cataclysmic variables

NASA Astrophysics Data System (ADS)

Torres, Manuel; Gaensicke, Boris; Rodriguez-Gil, Pablo; Long, Knox; Marsh, Tom; Steeghs, Danny; Munoz-Darias, Teodoro; Shahbaz, Tariq; Schmidtobreick, Linda; Schreiber, Matthias

2009-02-01

SW Sextantis stars are a relatively large group of cataclysmic variables (CVs) which plays a fundamental role in our understanding of CV structure and evolution. Very little is known about the properties of their accreting white dwarfs and their donor stars, as the stellar components are usually outshone by an extremely bright accretion flow. Consequently, a proper assesment of their evolutionary state is illusionary. We are monitoring the brightness of a number of SW Sex stars and request here Gemini/GMOS-N ToO time to obtain orbital phase-resolved spectroscopy if one of them enters a low state, since this is the only opportunity for studying the stellar components individually. These data will be used to accurately measure the binary parameters, white dwarf temperature, and distance to the system for a SW Sex star for the first time. The measured stellar masses and radii will especially be a precious input to the theory of compact binary evolution as a whole.

Voyager 1 Near the heliopause

DOE PAGES

Borovikov, S. N.; Pogorelov, N. V.

2014-02-18

Recent observations from the Voyager 1 spacecraft show that it is sampling the local interstellar medium (LISM). This is quite surprising because no realistic, steady-state model of the solar wind (SW) interaction with the LISM gives an inner heliosheath width as narrow as ~30 AU. This includes models that assume a strong redistribution of the ion energy to the tails in the pickup ion distribution function. We show that the heliopause (HP), which separates the SW from the LISM, is not a smooth tangential discontinuity, but rather a surface subject to Rayleigh-Taylor-type instabilities which can result in LISM material penetrationmore » deep inside the SW. We also show that the HP flanks are always subject to a Kelvin-Helmholtz instability. The instabilities are considerably suppressed near the HP nose by the heliospheric magnetic field in steady-state models, but reveal themselves in the presence of solar cycle effects. Here we argue that Voyager 1 may be in one such instability region and is therefore observing plasma densities much higher than those in the pristine SW. Lastly, these results may explain the early penetration of Voyager 1 into the LISM. They also show that there is a possibility that the spacecraft may start sampling the SW again before it finally leaves the heliosphere.« less

The SW Sex Phenomenon as an Evolutionary Stage of Cataclysmic Variables

NASA Astrophysics Data System (ADS)

Schmidtobreick, L.

From recent large observing campaigns, one finds that nearly all non- or weakly magnetic cataclysmic variables in the orbital period range between 2.8 and 4 hours are of SW Sex type and as such experience very high mass transfer rates. The evolution of cataclysmic variables as for any interacting binary is driven by angular momentum loss which results in a decrease of the orbital period on evolutionary time scales. In particular, all long-period systems need to cross the SW Sex regime of the orbital period distribution before entering the period gap. This makes the SW Sex phenomenon an evolutionary stage in the life of a cataclysmic variable. Here, I present a short overview of the current state of research on these systems.

Flexible, fast and accurate sequence alignment profiling on GPGPU with PaSWAS.

PubMed

Warris, Sven; Yalcin, Feyruz; Jackson, Katherine J L; Nap, Jan Peter

2015-01-01

To obtain large-scale sequence alignments in a fast and flexible way is an important step in the analyses of next generation sequencing data. Applications based on the Smith-Waterman (SW) algorithm are often either not fast enough, limited to dedicated tasks or not sufficiently accurate due to statistical issues. Current SW implementations that run on graphics hardware do not report the alignment details necessary for further analysis. With the Parallel SW Alignment Software (PaSWAS) it is possible (a) to have easy access to the computational power of NVIDIA-based general purpose graphics processing units (GPGPUs) to perform high-speed sequence alignments, and (b) retrieve relevant information such as score, number of gaps and mismatches. The software reports multiple hits per alignment. The added value of the new SW implementation is demonstrated with two test cases: (1) tag recovery in next generation sequence data and (2) isotype assignment within an immunoglobulin 454 sequence data set. Both cases show the usability and versatility of the new parallel Smith-Waterman implementation.

Speciation at the Mogollon Rim in the Arizona Mountain Kingsnake (Lampropeltis pyromelana).

PubMed

Burbrink, Frank T; Yao, Helen; Ingrasci, Matthew; Bryson, Robert W; Guiher, Timothy J; Ruane, Sara

2011-09-01

Studies of speciation and taxon delimitation are usually decoupled. Combining these methods provides a stronger theoretical ground for recognizing new taxa and understanding processes of speciation. Using coalescent methods, we examine speciation, post-speciation population demographics, and taxon delimitation in the Arizona Mountain Kingsnake (Lampropeltis pyromelana), a species restricted to high elevations in southwestern United States and northern Mexico (SW). These methods provide a solid foundation for understanding how biogeographic barriers operate at the regional scale in the SW. Bayesian species delimitation methods, using three loci from samples of L. pyromelana taken throughout their range, show strong support for the existence of two species that are separated by low elevation habitats found between the Colorado Plateau/ Mogollon Rim and the Sierra Madre Occidental. Our results suggest an allopatric mode of speciation given the near absence of gene flow over time, which resulted in two lineages of unequal population sizes. Speciation likely occurred prior to the Pleistocene, during the aridification of the SW and/or the uplift of the Colorado Plateau, and while these species occupy similar high-elevation niches, they are isolated by xeric conditions found in the intervening low deserts. Furthermore, post-speciation demographics suggest that populations of both lineages were not negatively impacted by climate change throughout the Pleistocene. Finally, our results suggest that at least for this group, where divergence is old and gene flow is low, Bayesian species delimitation performs well. Copyright © 2011 Elsevier Inc. All rights reserved.

Examining the Association Between Implementation and Outcomes

PubMed Central

Pas, Elise T.; Bradshaw, Catherine P.

2012-01-01

Although there is an established literature supporting the efficacy of a variety of prevention programs, there has been less empirical work on the tran of such research to everyday practice or when scaled-up state-wide. There is a considerable need for more research on factors that enhance implementation of programs and optimize outcomes, particularly in school settings. The current paper examines how the implementation fidelity of an increasingly popular and widely disseminated prevention model called, School-wide Positive Behavioral Interventions and Supports (SW-PBIS), relates to student outcomes within the context of a state-wide scale-up effort. Data come from a scale-up effort of SW-PBIS in Maryland; the sample included 421 elementary and middle schools trained in SW-PBIS. SW-PBIS fidelity, as measured by one of three fidelity measures, was found to be associated with higher math achievement, higher reading achievement, and lower truancy. School contextual factors were related to implementation levels and outcomes. Implications for scale-up efforts of behavioral and mental health interventions and measurement considerations are discussed. PMID:22836758

Groundwater-Surface Water Interactions and Downstream Transport of Water, Heat, and Solutes in a Hydropeaked River

NASA Astrophysics Data System (ADS)

Ferencz, S. B.; Cardenas, M. B.; Neilson, B. T.; Watson, J.

2017-12-01

A majority of the world's largest river systems are regulated by dams. In addition to being used for water resources management and flood prevention, many large dams are also used for hydroelectric power generation. In the United States, dams account for 7% of domestic electricity, and hydropower accounts for 16% of worldwide electricity production. To help meet electricity demand during peak usage times, hydropower utilities often increase their releases of water during high demand periods. This practice, termed hydropeaking, can cause large transient flow regimes downstream of hydroelectric dams. These transient flow increases can result in order of magnitude daily fluctuations in discharge, and the released water can have different thermal and chemical properties than ambient river water. As hydropeaking releases travel downstream, the temporary rise in stage and increase in discharge can enhance surface water-groundwater (SW-GW) exchange between the river and its alluvial aquifer. This dam-induced SW-GW exchange, combined with hydrodynamic attenuation and heat exchange processes, result in complex responses downstream. The dam-regulated Lower Colorado River downstream of Austin, TX was used as a natural laboratory to observe SW-GW interactions and downstream transport of water, heat, and solutes under hydropeaking conditions. To characterize SW-GW interactions, well transects were installed in the banks of the river to observe exchanges between the river and alluvial aquifer. The well transects were installed at three different distances from the dam (15km, 35km, and 80km). At each well transect conductivity, temperature, and pressure sensors were deployed in the monitoring wells and in the channel. Additional conductivity and temperature sensors were deployed along the study reach to provide a more detailed record of heat and solute transport during hydropeaking releases. The field data spans over two months of daily dam releases that were punctuated by two large natural storm events. To our knowledge, this study is the first to use multiple downstream field sites to characterize how dam-induced SW-GW interactions and in-stream temperature and solute transport behave under hydropeaking conditions.

Bichromatic Sisyphus Cooling

NASA Astrophysics Data System (ADS)

Cashen, M.; Yatsenko, L.; Metcalf, H.

2001-05-01

Sisyphus cooling arises when the conservative dipole force of a monochromatic optical standing wave (SW) is modified by optical pumping among multiple ground state sublevels at low intensity(J. Dalibard and C. Cohen-Tannoudji, J. Opt. Soc. B6), 2023 (1989)., or among dressed state manifolds at high intensity(A. Aspect et al., Phys. Rev. Lett. 57), 1688 (1986). As part of our ongoing exploration of optical forces in non-monochromatic light, we have discovered a new type of Sisyphus cooling in a two-level atom where the optical pumping is driven by a second SW produced as a sideband from weak frequency modulation. Each beam of the carrier's SW has a Rabi frequency Ωc ~ 20 γ and is tuned below atomic resonance by δc ~ -38 γ. Thus the light shift at the antinodes is ω_c^ls ~ 8.6 γ. For the sideband, Ωs ~ 1.4 γ and δs ~ +1 γ so ω_s^ls ~ 1 γ. The resulting forces satisfy Fc > 8 F_s. By contrast, the excitation rate γ_s^p > 2 γ_c^p. We choose the relative spatial phase of the SW's to be π, so moving atoms are most likely to be excited at the red-tuned carrier nodes, and thus they climb more hills than they descend. We observe transverse cooling of a beam of He metastables when δc < 0 and heating otherwise, in contrast to Ref. 3 because here the excitation is at the nodes of the high intensity carrier SW. We also observe channeling of the slow atoms in the carrier's SW.

Influence of axial tensile strain on the electronic and structural properties as well as NO gas sensitivity and reactivity of C-doped SW-BNNTs

NASA Astrophysics Data System (ADS)

Roohi, Hossein; Maleki, Layla

2017-11-01

The insulating character of BNNTs strongly imposes a great restriction on their applicability in nano-electronic devices. Therefore, it is desirable to find the practical routes for reducing the H-L gap. In this work, we demonstrate that the structural and electronic properties of the C-doped SW-BNNT can be significantly engineered and tuned by applying the axial tensile strain. Defect formation energies, cohesive energies, dipole moments, NBO charges, and global reactivity descriptors for un-doped SW-BNNT and C1-3-doped SW-BNNTs are calculated upon the axial strain. The B3LYP/6-31 +G(d) calculated H-L gap for five C-doped SW-BNNTs are expected to be smaller than that of un-doped SW-BNNT. At 10% axial tensile strain, CB NT is a suitable conductance with a 1.947 eV H-L gap. The decrease in the H-L gap for 2C-doped CN,B (-0.839 eV) NT within 15% strain is greater than 1C- and 3C-doped SW-BNNTs. In the second part of this work, reactivity and the sensitivity of strained C1-2-doped SW-BNNTs toward NO gas were evaluated at M06-2X/6-31 ++G(d,p) level of theory. Optimized structures, molecular graphs, adsorption energies (AE), dispersion corrected AEs, H-L gap, NBO charges, charge transfer values, density of states and electrostatic potentials were calculated. The strained C1-doped SW-BNNTs showed an increased ability for the sensitivity and adsorption of NO molecule, as compared with unstrained doped SW-BNNT. In general, the CN,B NTs have practically less potential for the adsorption of NO molecule than CB and CN ones.

A new method for quantifying and modeling large scale surface water inundation dynamics and key drivers using multiple time series of Earth observation and river flow data. A case study for Australia's Murray-Darling Basin

NASA Astrophysics Data System (ADS)

Heimhuber, Valentin; Tulbure, Mirela G.; Broich, Mark

2017-04-01

Periodically inundated surface water (SW) areas such as floodplains are hotspots of biodiversity and provide a broad range of ecosystem services but have suffered alarming declines in recent history. Large scale flooding events govern the dynamics of these areas and are a critical component of the terrestrial water cycle, but their propagation through river systems and the corresponding long term SW dynamics remain poorly quantified on continental or global scales. In this research, we used an unprecedented Landsat-based time series of SW maps (1986-2011), to develop statistical inundation models and quantify the role of driver variables across the Murray-Darling Basin (MDB) (1 million square-km), which is Australia's bread basket and subject to competing demands over limited water resources. We fitted generalized additive models (GAM) between SW extent as the dependent variable and river flow data from 68 gauges, spatial time series of rainfall (P; interpolated gauge data), evapotranspiration (ET; AWRA-L land surface model) and soil moisture (SM; active passive microwave satellite remote sensing) as predictor variables. We used a fully directed and connected river network (Australian Geofabric) in combination with ancillary data, to develop a spatial modeling framework consisting of 18,521 individual modeling units. We then fitted individual models for all modeling units, which were made up of 10x10 km grid cells split into floodplain, floodplain-lake and non-floodplain areas, depending on the type of water body and its hydrologic connectivity to a gauged river. We applied the framework to quantify flood propagation times for all major river and floodplain systems across the MDB, which were in good accordance with observed travel times. After incorporating these flow lag times into the models, average goodness of fit was high across floodplains and floodplain-lake modeling units (r-squared > 0.65), which were primarily driven by river flow, and lower for non-floodplain areas (r-squared > 0.24), which were primarily driven by local rainfall. Our results indicate that local climate conditions (i.e. P, ET, SM) had more influence on SW dynamics in the northern compared to the southern MDB and were the most influential in the least regulated and most extended floodplains in the north-west. We also applied the statistical models of two floodplain areas with contrasting flooding regimes to predict SW extents of cloud-affected time steps in the Landsat time series during the large 2010 floods with high validated accuracy (r-squared > 0.97). Our findings illustrate that integrating multi-decadal time series of Earth observation data and in situ measurements with statistical modeling techniques can provide cost-effective tools for improving the management of limited SW resources and floods. The data-driven method is applicable to other large river basins and provides statistical models that can predict SW extent for cloud-affected Landsat observations or during the peak of floods and hence, allows a more detailed quantification of the dynamics of large floods compared to existing approaches. Future research will investigate the potential of image fusion techniques (i.e. ESTARFM) for improving the quantification of rapid changes in SW distribution by combining MODIS and Landsat imagery.

The Effect of the Leader in Me, a School-Wide Positive Behavior Intervention System (SW-PBIS), Based on Student Achievement and Office Discipline Referrals for Fifth Grade Students in a Rural Elementary School in North Central Washington State

ERIC Educational Resources Information Center

Miller, Christopher A.

2016-01-01

The purpose this study was to examine the implementation of The Leader in Me, a school-wide positive behavior intervention system (SW-PBIS), and analyze its impact on 5th grade students based on student achievement and office discipline referrals in a rural elementary school in North Central Washington state. The school was in the first year of…

Estimating the number of male sex workers with the capture-recapture technique in Nigeria.

PubMed

Adebajo, Sylvia B; Eluwa, George I; Tocco, Jack U; Ahonsi, Babatunde A; Abiodun, Lolade Y; Anene, Oliver A; Akpona, Dennis O; Karlyn, Andrew S; Kellerman, Scott

2013-12-01

Estimating the size of populations most affected by HIV such as men who have sex with men (MSM) though crucial for structuring responses to the epidemic presents significant challenges, especially in a developing society. Using capture-recapture methodology, the size of MSM-SW in Nigeria was estimated in three major cities (Lagos, Kano and Port Harcourt) between July and December 2009. Following interviews with key informants, locations and times when MSM-SW were available to male clients were mapped and designated as "hotspots". Counts were conducted on two consecutive weekends. Population estimates were computed using a standardized Lincoln formula. Fifty-six hotspots were identified in Kano, 38 in Lagos and 42 in Port Harcourt. On a given weekend night, Port Harcourt had the largest estimated population of MSM sex workers, 723 (95% CI: 594-892) followed by Lagos state with 620 (95%CI: 517-724) and Kano state with 353 (95%CI: 332-373). This study documents a large population of MSM-SW in 3 Nigerian cities where higher HIV prevalence among MSM compared to the general population has been documented. Research and programming are needed to better understand and address the health vulnerabilities that MSM-SW and their clients face.

49 CFR 830.5 - Immediate notification.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., NTSB headquarters is located at 490 L'Enfant Plaza, SW., Washington, DC 20594. Contact information for... unit, or air-driven generator to retain flight control or essential instruments; (ii) In-flight failure...

Supply Warehouse#3, SWMU 088 Operations, Maintenance, and Monitoring Report Kennedy Space Center, Florida

NASA Technical Reports Server (NTRS)

Murphy, Alex

2016-01-01

This document presents the findings, observations, and results associated with Operations, Maintenance, and Monitoring (OM&M) activities of Corrective Measures Implementation (CMI) activities conducted at Supply Warehouse #3 (SW3) located at John F. Kennedy Space Center (KSC), Florida from October 8, 2015, to September 12, 2016, and performance monitoring results for semi-annual sampling events conducted in March and September 2016. The primary objective of SW3 CMI is to actively decrease concentrations of trichloroethene (TCE) and vinyl chloride (VC) to less than Florida Department of Environmental Protection (FDEP) Natural Attenuation Default Concentrations (NADCs), and the secondary objective is to reduce TCE, cis-1,2-dichloroethene (cDCE), trans-1,2-dichloroethene (tDCE), 1,1-dichloroethene (11DCE), and VC concentrations to less than FDEP Groundwater Cleanup Target Levels (GCTLs). The SW3 facility has been designated Solid Waste Management Unit (SWMU) 088 under KSC's Resource Conservation and Recovery Act (RCRA) Corrective Action Program. Based on the results to date, the SW3 air sparging (AS) system is operating at or below the performance criteria as presented in the 2008 SW3 Corrective Measures Implementation (CMI) Work Plan and 2009 and 2012 CMI Work Plan Addenda. Since the start of AS system operations on December 19, 2012, through the September 2016 groundwater sampling event, TCE concentrations have decreased to less than the GCTL in all wells within the Active Remediation Zone (ARZ), and VC results remain less than NADC but greater than GCTL. Based on these results, team consensus was reached at the October 2016 KSC Remediation Team (KSCRT) meeting to continue AS system operations and semi-annual performance monitoring of volatile organic compounds in March 2017 at ten monitoring wells at select locations, and in September 2017 at four monitoring wells at select locations to reduce VC concentrations to below GCTL. Additionally, surface water samples will be collected at locations SW0001, SW0002, and SW0003 during both the March and September 2017 events. Team consensus was also reached at the October 2017 KSCRT meeting to continue with operation and maintenance (O&M) of the AS system at SW3.

The complexity of millennial-scale variability in southwestern Europe during MIS 11

NASA Astrophysics Data System (ADS)

Oliveira, Dulce; Desprat, Stéphanie; Rodrigues, Teresa; Naughton, Filipa; Hodell, David; Trigo, Ricardo; Rufino, Marta; Lopes, Cristina; Abrantes, Fátima; Sánchez Goñi, Maria Fernanda

2016-11-01

Climatic variability of Marine Isotope Stage (MIS) 11 is examined using a new high-resolution direct land-sea comparison from the SW Iberian margin Site U1385. This study, based on pollen and biomarker analyses, documents regional vegetation, terrestrial climate and sea surface temperature (SST) variability. Suborbital climate variability is revealed by a series of forest decline events suggesting repeated cooling and drying episodes in SW Iberia throughout MIS 11. Only the most severe events on land are coeval with SST decreases, under larger ice volume conditions. Our study shows that the diverse expression (magnitude, character and duration) of the millennial-scale cooling events in SW Europe relies on atmospheric and oceanic processes whose predominant role likely depends on baseline climate states. Repeated atmospheric shifts recalling the positive North Atlantic Oscillation mode, inducing dryness in SW Iberia without systematical SST changes, would prevail during low ice volume conditions. In contrast, disruption of the Atlantic meridional overturning circulation (AMOC), related to iceberg discharges, colder SST and increased hydrological regime, would be responsible for the coldest and driest episodes of prolonged duration in SW Europe.

Army Science Board (ASB) Report of the AD HOC Subgroup on Water Supply and Management on Army Installations in the Western United States

DTIC Science & Technology

1988-02-01

Operations and Maintenance ( O &M), Proving Grounds (PG), Research and Development (R&D), Surface Water (SW), Technical Manual (TM), Terms of Reference...presentation (Chair and HODA Staff Assistant o !y% 3 i. EXECUTIVE SUMMARY Water is a strategic resource for the Army. It is essential for industrial...GRANDE REGION lla qLL c5(5 eO e0€••oo ac’ 00 :42 t4 c4 ř m "- n "ciis M C4 00.4 -4. 00 0 . 𔃺 o ro o j • •" o 00’- total water withdrawn for

31 CFR Appendix J to Subpart C of... - Office of the Comptroller of the Currency

Code of Federal Regulations, 2010 CFR

2010-07-01

... head of the organizational unit having immediate custody of the records requested or the delegate of..., Communications Division, Office of the Comptroller of the Currency, 250 E Street, SW, Washington, DC 20219. 3... organizational unit having immediate custody of the records or the delegate of that official. Requests for...

Comparison of shear wave velocity measurements assessed with two different ultrasound systems in an ex-vivo tendon strain phantom.

PubMed

Rosskopf, Andrea B; Bachmann, Elias; Snedeker, Jess G; Pfirrmann, Christian W A; Buck, Florian M

2016-11-01

The purpose of this study is to compare the reliability of SW velocity measurements of two different ultrasound systems and their correlation with the tangent traction modulus in a non-static tendon strain model. A bovine tendon was fixed in a custom-made stretching device. Force was applied increasing from 0 up to 18 Newton. During each strain state the tangent traction modulus was determined by the stretcher device, and SW velocity (m/s) measurements using a Siemens S3000 and a Supersonic Aixplorer US machine were done for shear modulus (kPa) calculation. A strong significant positive correlation was found between SW velocity assessed by the two ultrasound systems and the tangent traction modulus (r = 0.827-0.954, p < 0.001), yet all SW velocity-based calculations underestimated the reference tissue tangent modulus. Mean difference of SW velocities with the S3000 was 0.44 ± 0.3 m/s (p = 0.002) and with the Aixplorer 0.25 ± 0.3 m/s (p = 0.034). Mean difference of SW velocity between the two US-systems was 0.37 ± 0.3 m/s (p = 0.012). In conclusion, SW velocities are highly dependent on mechanical forces in the tendon tissue, but for controlled mechanical loads appear to yield reproducible and comparable measurements using different US systems.

39. CAVEMAN BRIDGE, ROGUE RIVER, OREGON STATE HIGHWAY 199. GRANTS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

39. CAVEMAN BRIDGE, ROGUE RIVER, OREGON STATE HIGHWAY 199. GRANTS PASS, JOSEPHINE COUNTY, OREGON. LOOKING SW. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

Application of a weighted-averaging method for determining paleosalinity: a tool for restoration of south Florida's estuaries

USGS Publications Warehouse

Wingard, G.L.; Hudley, J.W.

2012-01-01

A molluscan analogue dataset is presented in conjunction with a weighted-averaging technique as a tool for estimating past salinity patterns in south Florida’s estuaries and developing targets for restoration based on these reconstructions. The method, here referred to as cumulative weighted percent (CWP), was tested using modern surficial samples collected in Florida Bay from sites located near fixed water monitoring stations that record salinity. The results were calibrated using species weighting factors derived from examining species occurrence patterns. A comparison of the resulting calibrated species-weighted CWP (SW-CWP) to the observed salinity at the water monitoring stations averaged over a 3-year time period indicates, on average, the SW-CWP comes within less than two salinity units of estimating the observed salinity. The SW-CWP reconstructions were conducted on a core from near the mouth of Taylor Slough to illustrate the application of the method.

GOLD CREW SW

EPA Pesticide Factsheets

Technical product bulletin: this surface washing agent for oil spill cleanups should be applied through hand pump sprayer and allowed to presoak, time depending on type of oil and weather conditions. Then apply through power washer or steam powered unit.

Detection of motor imagery of swallow EEG signals based on the dual-tree complex wavelet transform and adaptive model selection

NASA Astrophysics Data System (ADS)

Yang, Huijuan; Guan, Cuntai; Sui Geok Chua, Karen; San Chok, See; Wang, Chuan Chu; Kok Soon, Phua; Tang, Christina Ka Yin; Keng Ang, Kai

2014-06-01

Objective. Detection of motor imagery of hand/arm has been extensively studied for stroke rehabilitation. This paper firstly investigates the detection of motor imagery of swallow (MI-SW) and motor imagery of tongue protrusion (MI-Ton) in an attempt to find a novel solution for post-stroke dysphagia rehabilitation. Detection of MI-SW from a simple yet relevant modality such as MI-Ton is then investigated, motivated by the similarity in activation patterns between tongue movements and swallowing and there being fewer movement artifacts in performing tongue movements compared to swallowing. Approach. Novel features were extracted based on the coefficients of the dual-tree complex wavelet transform to build multiple training models for detecting MI-SW. The session-to-session classification accuracy was boosted by adaptively selecting the training model to maximize the ratio of between-classes distances versus within-class distances, using features of training and evaluation data. Main results. Our proposed method yielded averaged cross-validation (CV) classification accuracies of 70.89% and 73.79% for MI-SW and MI-Ton for ten healthy subjects, which are significantly better than the results from existing methods. In addition, averaged CV accuracies of 66.40% and 70.24% for MI-SW and MI-Ton were obtained for one stroke patient, demonstrating the detectability of MI-SW and MI-Ton from the idle state. Furthermore, averaged session-to-session classification accuracies of 72.08% and 70% were achieved for ten healthy subjects and one stroke patient using the MI-Ton model. Significance. These results and the subjectwise strong correlations in classification accuracies between MI-SW and MI-Ton demonstrated the feasibility of detecting MI-SW from MI-Ton models.

Late Cenozoic extensional faulting in Central-Western Peloponnesus, Greece

NASA Astrophysics Data System (ADS)

Skourtsos, E.; Fountoulis, I.; Mavroulis, S.; Kranis, H.

2012-04-01

A series of forearc-dipping, orogen-parallel extensional faults are found in the central-western Peloponnesus, (south-western Aegean) which control the western margin of Mt Mainalon. The latter comprises HP/LT rocks of the Phyllites-Quartzites Unit (PQ), overlain by the carbonates and flysch of the Tripolis Unit while the uppermost nappe is the Pindos Unit, a sequence of Mesozoic pelagic sequence, topped by a Paleocene flysch. Most of the extensional structures were previously thought of as the original thrust between the Pindos and Tripolis Units. However, the cross-cutting relationships among these structures indicate that these are forearc (SW-dipping) extensional faults, downthrowing the Pindos thrust by a few tens or hundreds of meters each, rooting onto different levels of the nappe pile. In SW Mainalon the lowermost of the extensional faults is a low-angle normal fault dipping SW juxtaposing the metamorphic rocks of the PQ Unit against the non-metamorphic sequence of the Tripolis Unit. High-angle normal faults, found further to the west, have truncated or even sole onto the low-angle ones and control the eastern margin of the Quaternary Megalopolis basin. All these extensional structures form the eastern boundary of a series of Neogene-Quaternary tectonic depressions, which in turn are separated by E-W horsts. In the NW, these faults are truncated by NE to NNE-striking, NW-dipping faults, which relay the whole fault activity to the eastern margin of the Pyrgos graben. The whole extensional fault architecture has resulted (i) in the Pindos thrust stepping down from altitudes higher than 1000 m in Mainalon in the east, to negative heights in North Messinia and Southern Ilia in the west; and (ii) the gradual disappearance of the Phyllite-Quartzite metamorphics of Mainalon towards the west. The combination of these extensional faults (which may reach down to the Ionian décollement) with the low-angle floor thrusts of the Pindos, Tripolis and Ionian Units leads to additional ENE-WSW shortening, normal to the Hellenic Arc, west of the Peloponnesus.

Using ISCCP Weather States to Decompose Cloud Radiative Effects

NASA Technical Reports Server (NTRS)

Oreopoulos, L.; Rossow, W. B.

2012-01-01

The presentation will examine the shortwave (SW) and longwave (LW) cloud radiative effect CRE (aka "cloud radiative forcing") at the top-of-the-atmosphere and surface of ISCCP weather states (aka "cloud regimes") in three distinct geographical zones, one tropical and two mid-latitude. Our goal is to understand and quantify the contribution of the different cloud regimes to the planetary radiation budget. In the tropics we find that the three most convectively active states are the ones with largest SW, LW and net TOA CRE contributions to the overall daytime tropical CRE budget. They account for 59%, 71% and 55% of the total CRE, respectively. The boundary layer-dominated weather states account for only 34% of the total SW CRE and 41% of the total net CRE, so to focus only on them in cloud feedback studies may be imprudent. We also find that in both the northern and southern midlatitude zones only two weather states, the first and third most convectively active with large amounts of nimbostratus-type clouds, contribute ",40% to both the SW and net TOA CRE budgets, highlighting the fact that cloud regimes associated with frontal systems are not only important for weather (precipitation) but also for climate (radiation budget). While all cloud regimes in all geographical zones have a slightly larger SFC than TOA SW CRE, implying cooling of the surface and slight warming of the atmosphere, their LW radiative effects are more subtle: in the tropics the weather states with plentiful high clouds warm the atmosphere while those with copious amounts of low clouds cool the atmosphere. In both midlatitude zones only the weather states with peak cloud fractions at levels above 440 mbar warm the atmosphere while all the rest cool it. These results make the connection of the contrasting CRE effects to the atmospheric dynamics more explicit - "storms" tend to warm the atmosphere whereas fair weather clouds cool it, suggesting a positive feedback of clouds on weather systems. The breakdown of CRE by cloud regime are however not entirely similar between the two midlatitude zones. Despite the existence of an additional state in the nort!lern midlatitudes, only four weather states have net daytime CREs with absolute values above 100 Watts per square meter compared to six in the south. This reminds us that the environment where clouds occur also has a crucial role in determining their radiative effects. All the above make evident that reproducing grand averages of current CRE by climate models in only part of the challenge. If existing cloud regimes and shifts in their distributions and frequency of occurrence in a changed climate are not properly simulated, the radiative role of clouds will not be adequately predicted.

Geological Features Mapping Using PALSAR-2 Data in Kelantan River Basin, Peninsular Malaysia

NASA Astrophysics Data System (ADS)

Pour, A. B.; Hashim, M.

2016-09-01

In this study, the recently launched Phased Array type L-band Synthetic Aperture Radar-2 (PALSAR-2) onboard the Advanced Land Observing Satellite-2 (ALOS-2), remote sensing data were used to map geologic structural and topographical features in the Kelantan river basin for identification of high potential risk and susceptible zones for landslides and flooding areas. A ScanSAR and two fine mode dual polarization level 3.1 images cover Kelantan state were processed for comprehensive analysis of major geological structures and detailed characterizations of lineaments, drainage patterns and lithology at both regional and district scales. Red-Green-Blue (RGB) colour-composite was applied to different polarization channels of PALSAR-2 data to extract variety of geological information. Directional convolution filters were applied to the data for identifying linear features in particular directions and edge enhancement in the spatial domain. Results derived from ScanSAR image indicate that lineament occurrence at regional scale was mainly linked to the N-S trending of the Bentong-Raub Suture Zone (BRSZ) in the west and Lebir Fault Zone in the east of the Kelantan state. Combination of different polarization channels produced image maps contain important information related to water bodies, wetlands and lithological units for the Kelantan state using fine mode observation data. The N-S, NE-SW and NNE-SSW lineament trends were identified in the study area using directional filtering. Dendritic, sub-dendritic and rectangular drainage patterns were detected in the Kelantan river basin. The analysis of field investigations data indicate that many of flooded areas were associated with high potential risk zones for hydro-geological hazards such as wetlands, urban areas, floodplain scroll, meander bend, dendritic and sub-dendritic drainage patterns, which are located in flat topograghy regions. Numerous landslide points were located in rectangular drainage system that associated with topographic slope of metamorphic and Quaternary rock units. Some large landslides were associated with N-S, NNE-SSW and NE-SW trending fault zones. Consequently, structural and topographical geology maps were produced for Kelantan river basin using PALSAR-2 data, which could be broadly applicable for landslide hazard mapping and identification of high potential risk zone for hydro-geological hazards.

The use of feasibility studies for stepped-wedge cluster randomised trials: protocol for a review of impact and scope

PubMed Central

Kristunas, Caroline A; Hemming, Karla; Eborall, Helen C; Gray, Laura J

2017-01-01

Introduction The stepped-wedge cluster randomised trial (SW-CRT) is a complex design, for which many decisions about key design parameters must be made during the planning. These include the number of steps and the duration of time needed to embed the intervention. Feasibility studies are likely to be useful for informing these decisions and increasing the likelihood of the main trial's success. However, the number of feasibility studies being conducted for SW-CRTs is currently unknown. This review aims to establish the number of feasibility studies being conducted for SW-CRTs and determine which feasibility issues are commonly investigated. Methods and analysis Fully published feasibility studies for SW-CRTs will be identified, according to predefined inclusion criteria, from searches conducted in Ovid MEDLINE, Scopus, Embase and PsycINFO. To also identify and gain information on unpublished feasibility studies the following will be contacted: authors of published SW-CRTs (identified from the most recent systematic reviews); contacts for registered SW-CRTs (identified from clinical trials registries); lead statisticians of UK registered clinical trials units and researchers known to work in the area of SW-CRTs. Data extraction will be conducted independently by two reviewers. For the fully published feasibility studies, data will be extracted on the study characteristics, the rationale for the study, the process for determining progression to a main trial, how the study informed the main trial and whether the main trial went ahead. The researchers involved in the unpublished feasibility studies will be contacted to elicit the same information. A narrative synthesis will be conducted and provided alongside a descriptive analysis of the study characteristics. Ethics and dissemination This review does not require ethical approval, as no individual patient data will be used. The results of this review will be published in an open-access peer-reviewed journal. PMID:28765139

Increase of gap junction activities in SW480 human colorectal cancer cells.

PubMed

Bigelow, Kristina; Nguyen, Thu A

2014-07-09

Colorectal cancer is one of the most common cancers in the United States with an early detection rate of only 39%. Colorectal cancer cells along with other cancer cells exhibit many deficiencies in cell-to-cell communication, particularly gap junctional intercellular communication (GJIC). GJIC has been reported to diminish as cancer cells progress. Gap junctions are intercellular channels composed of connexin proteins, which mediate the direct passage of small molecules from one cell to the next. They are involved in the regulation of the cell cycle, cell differentiation, and cell signaling. Since the regulation of gap junctions is lost in colorectal cancer cells, the goal of this study is to determine the effect of GJIC restoration in colorectal cancer cells. Gap Junction Activity Assay and protein analysis were performed to evaluate the effects of overexpression of connexin 43 (Cx43) and treatment of PQ1, a small molecule, on GJIC. Overexpression of Cx43 in SW480 colorectal cancer cells causes a 6-fold increase of gap junction activity compared to control. This suggests that overexpressing Cx43 can restore GJIC. Furthermore, small molecule like PQ1 directly targeting gap junction channel was used to increase GJIC. Gap junction enhancers, PQ1, at 200 nM showed a 4-fold increase of gap junction activity in SW480 cells. A shift from the P0 to the P2 isoform of Cx43 was seen after 1 hour treatment with 200 nM PQ1. Overexpression of Cx43 and treatment of PQ1 can directly increase gap junction activity. The findings provide an important implication in which restoration of gap junction activity can be targeted for drug development.

Modeling multidecadal surface water inundation dynamics and key drivers on large river basin scale using multiple time series of Earth-observation and river flow data

NASA Astrophysics Data System (ADS)

Heimhuber, V.; Tulbure, M. G.; Broich, M.

2017-02-01

Periodically inundated floodplain areas are hot spots of biodiversity and provide a broad range of ecosystem services but have suffered alarming declines in recent history. Despite their importance, their long-term surface water (SW) dynamics and hydroclimatic drivers remain poorly quantified on continental scales. In this study, we used a 26 year time series of Landsat-derived SW maps in combination with river flow data from 68 gauges and spatial time series of rainfall, evapotranspiration and soil moisture to statistically model SW dynamics as a function of key drivers across Australia's Murray-Darling Basin (˜1 million km2). We fitted generalized additive models for 18,521 individual modeling units made up of 10 × 10 km grid cells, each split into floodplain, floodplain-lake, and nonfloodplain area. Average goodness of fit of models was high across floodplains and floodplain-lakes (r2 > 0.65), which were primarily driven by river flow, and was lower for nonfloodplain areas (r2 > 0.24), which were primarily driven by rainfall. Local climate conditions were more relevant for SW dynamics in the northern compared to the southern basin and had the highest influence in the least regulated and most extended floodplains. We further applied the models of two contrasting floodplain areas to predict SW extents of cloud-affected time steps in the Landsat series during the large 2010 floods with high validated accuracy (r2 > 0.97). Our framework is applicable to other complex river basins across the world and enables a more detailed quantification of large floods and drivers of SW dynamics compared to existing methods.

A Language Skills Program for Secondary LD Students.

ERIC Educational Resources Information Center

Howe, Bill

1982-01-01

A program was developed to increase the receptive and expressive language skills of 24 secondary learning-disabled students. Program units covered word sorting, sight-word vocabulary, key-word reading, reading rate, reading comprehension, listening, and writing. (Author/SW)

77 FR 25155 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-27

... DEPARTMENT OF ENERGY Energy Efficiency and Renewable Energy State Energy Advisory Board (STEAB... teleconference. SUMMARY: This notice announces a teleconference call of the State Energy Advisory Board (STEAB... Renewable Energy, 1000 Independence Ave., SW., Washington, DC 20585. Phone number is (202) 287-1644...

78 FR 20311 - State Energy Advisory Board; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-04

... DEPARTMENT OF ENERGY Energy Efficiency and Renewable Energy State Energy Advisory Board; Meeting.... SUMMARY: This notice announces a Board meeting of the State Energy Advisory Board (STEAB). The Federal... Energy, 1000 Independence Ave SW., Washington, DC 20585. SUPPLEMENTARY INFORMATION: Purpose of the Board...

77 FR 54573 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-05

... DEPARTMENT OF ENERGY Office of Energy Efficiency and Renewable Energy State Energy Advisory Board... open teleconference. SUMMARY: This notice announces a teleconference call of the State Energy Advisory... Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number: (202) 287-1644...

76 FR 36103 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-21

... DEPARTMENT OF ENERGY Office of Energy Efficiency and Renewable Energy State Energy Advisory Board... Open Teleconference. SUMMARY: This notice announces an open teleconference call of the State Energy... Energy Efficiency and Renewable Energy, 1000 Independence Ave, SW., Washington DC, 20585 or telephone...

77 FR 39690 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-05

... DEPARTMENT OF ENERGY State Energy Advisory Board (STEAB) AGENCY: Energy Efficiency and Renewable... teleconference call of the State Energy Advisory Board (STEAB). The Federal Advisory Committee Act (Pub. L. 92... Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC...

MICRO AUTO GASIFICATION SYSTEM: EMISSIONS ...

EPA Pesticide Factsheets

A compact, CONEX-housed waste to energy unit, Micro Auto Gasification System (MAGS), was characterized for air emissions from burning of military waste types. The MAGS unit is a dual chamber gasifier with a secondary diesel-fired combustor. Eight tests were conducted with multiple waste types in a 7-day period at the Kilauea Military Camp in Hawai’i. The emissions characterized were chosen based on regulatory emissions limits as well as their ability to cause adverse health effects on humans: particulate matter (PM), mercury, heavy metals, volatile organic compounds (VOCs), polyaromatic hydrocarbons (PAHs), and polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). Three military waste feedstock compositions reflecting the variety of wastes to be encountered in theatre were investigated: standard waste (SW), standard waste with increased plastic content (HP), standard waste without SW food components but added first strike ration (FSR) food and packaging material (termed FSR). A fourth waste was collected from the Kilauea dumpster that served the dining facility and room lodging (KMC). Limited scrubber water and solid ash residue samples were collected to obtain a preliminary characterization of these effluents/residues.Gasifying SW, HP, and KMC resulted in similar PCDD/PCDF stack concentrations, 0.26-0.27 ng TEQ/m3 at 7% O2, while FSR waste generated a notably higher stack concentration of 0.68 ng TEQ/m3 at 7% O2. The PM emission

Kinetic theory for the formation of diamond nanothreads with desired configurations: a strain-temperature controlled phase diagram.

PubMed

Gao, Junfeng; Zhang, Gang; Yakobson, Boris I; Zhang, Yong-Wei

2018-05-24

Diamond nanothreads (DNTs) are a brand-new one-dimensional carbon nanomaterial that was synthesized recently by compressing benzene. Compared with sp2 carbon nanotubes, DNTs may possess a much higher interfacial load-transfer ability. However, previous studies have shown that the mechanical properties of DNTs are highly sensitive to the composition of Stone-Wales (SW) transformed sites. Up to now, it remained unclear what roles SWs play in the structure stability and how to engineer its molecular structure for novel mechanical properties. Using ab initio calculations, here we show that the most stable structure of a DNT is composed of alternative SW and hydrogenated carbon nanotube (3,0) units, suggesting that SW plays an essential role in stabilizing DNT. Interestingly, we found that the SW transition barrier is a nearly linear function of the applied strain, enabling strain engineering of its molecular structure. To do so, we propose a strain-temperature-stretching rate phase diagram to guide the construction of desired molecular structures to achieve superplastic behavior of DNTs. Our findings not only enrich our understanding of this novel carbon material, but also provide a strategy to control its structural and mechanical properties for novel applications, such as energy absorption, energy storage and materials reinforcement.

Mississippian lamprophyre dikes in western Sierras Pampeanas, Argentina: Evidence of transtensional tectonics along the SW margin of Gondwana

NASA Astrophysics Data System (ADS)

Martina, Federico; Canelo, Horacio N.; Dávila, Federico M.; de Hollanda, María Helena M.; Teixeira, Wilson

2018-04-01

In the Famatina range, Sierras Pampeanas of Argentina (SW Gondwana), subvertical calc-alkaline lamprophyric dike swarms crop out through >300 km. The dikes cut Ordovician units with a prominent NW-SE trending and are covered by continental sedimentary successions of Pennsylvanian to Permian age. The dikes show a strong structural control associated with Riedel fault systems. Detailed field analysis suggested a ∼N-S opening direction oblique to the attitude of dike walls and a left-lateral transtensional tectonics during the emplacement. 40Ar/39Ar geochronology of a lamprophyric sample defined a crystallization age (plateau; whole rock) of 357.1 ± 7.1 Ma (MSWD = 2.3). Coetaneous ductile zones with dominant strike-slip motion, documented along western Argentina for >600 km, suggest a regional event in SW Gondwana during the Mississippian. We propose that this deformation was the result of the counterclockwise fast rotation of Gondwana between 365 and 345 Ma, when the Famatina range and western Argentina occupied a sub-polar position. A transform margin along SW Gondwana better explains our (and others) data rather than a subduction margin. This scenario is also consistent with the occurrence of A-type granites and normal-fault basins within the foreland as well as bimodal volcanics.

The hot-spot environment of SW Sex in a low state

NASA Astrophysics Data System (ADS)

Groot, Paul J.; Rutten, René G. M.; van Paradijs, Jan

2000-04-01

Based on observations obtained with the 2.5m Isaac Newton Telescope we show that the characteristics of the SW Sex stars can be explained by the dominance of a `hot-spot' like feature in the accretion disk. In SW Sex this `hot-spot' region is located at a distance of 0.5 RL 1 from the white-dwarf and is best visible at phase ϕ=0.95. The location of the hot-spot as deduced from spectral eclipse mapping coincides with the formation site of the main emission lines. We deduce that this hot-spot region is formed by a shock, which we speculate to be the consequence of a high mass-transfer rate and a long spin-period of the non-magnetic white dwarf.

NPDES Permit for Sunlight Ranch Company, Little Horn Unit in Montana

EPA Pesticide Factsheets

Draft permit and statement of basis MT0029424 for a beef cattle feedlot located on the Crow Reservation at the SW ¼ of Section 3, NW 1/4 of Section 10, Township 9 South Range 34 East, Montana Principal Meridian.

14 CFR 156.2 - Letters of interest.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS STATE... Associate Administrator for Airports, Federal Aviation Administration, 800 Independence Avenue SW., Room... material to each State that submits a letter of interest to the Associate Administrator for Airports. ...

14 CFR 156.2 - Letters of interest.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS STATE... Associate Administrator for Airports, Federal Aviation Administration, 800 Independence Avenue SW., Room... material to each State that submits a letter of interest to the Associate Administrator for Airports. ...

14 CFR 156.2 - Letters of interest.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS STATE... Associate Administrator for Airports, Federal Aviation Administration, 800 Independence Avenue SW., Room... material to each State that submits a letter of interest to the Associate Administrator for Airports. ...

14 CFR 156.2 - Letters of interest.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS STATE... Associate Administrator for Airports, Federal Aviation Administration, 800 Independence Avenue SW., Room... material to each State that submits a letter of interest to the Associate Administrator for Airports. ...

14 CFR 156.2 - Letters of interest.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS STATE... Associate Administrator for Airports, Federal Aviation Administration, 800 Independence Avenue SW., Room... material to each State that submits a letter of interest to the Associate Administrator for Airports. ...

Enhancement of macroscopic quantum tunneling in the higher-order phase switches of Bi2212 intrinsic Josephson junctions

NASA Astrophysics Data System (ADS)

Kitano, Haruhisa; Yamaguchi, Ayami; Takahashi, Yusaku; Umegai, Shunpei; Watabe, Yuji; Ohnuma, Haruka; Hosaka, Kazutaka; Kakehi, Daiki

2018-03-01

The macroscopic quantum tunneling (MQT) in the current-biased intrinsic Josephson junctions (IJJs) of high-T c cuprates has attracted much attention for decades. Although the MQT for the phase switches from the zero to the first voltage state (1st SW) in the multiple-branched I-V curves is well explained by the conventional theory, the occurrence of MQT for the higher order switches such as the switch from the 1st to 2nd voltage state (2nd SW) has been still debated. Here, we present an experimental study on the phase switches of small IJJs fabricated from underdoped Bi2Sr2(Ca,Y)Cu2Oy. We observed the single photon transition between quantized energy levels in the 3rd phase switches at 59.15 GHz and 2 K. The comparison with the previous studies on the nearly optimal-doped Bi2Sr2CaCu2Oy clearly suggests a possibility that the MQT rate for the higher-order phase switches is commonly enhanced by the effective suppression of the energy barrier for the higher-order phase escape due to the phase-running state after the 1st SW, in spite of the large difference in a critical current density and T c.

VOCs Emissions from Multiple Wood Pellet Types and Concentrations in Indoor Air

PubMed Central

Soto-Garcia, Lydia; Ashley, William J.; Bregg, Sandar; Walier, Drew; LeBouf, Ryan; Hopke, Philip K.; Rossner, Alan

2016-01-01

Wood pellet storage safety is an important aspect for implementing woody biomass as a renewable energy source. When wood pellets are stored indoors in large quantities (tons) in poorly ventilated spaces in buildings, such as in basements, off-gassing of volatile organic compounds (VOCs) can significantly affect indoor air quality. To determine the emission rates and potential impact of VOC emissions, a series of laboratory and field measurements were conducted using softwood, hardwood, and blended wood pellets manufactured in New York. Evacuated canisters were used to collect air samples from the headspace of drums containing pellets and then in basements and pellet storage areas of homes and small businesses. Multiple peaks were identified during GC/MS and GC/FID analysis, and four primary VOCs were characterized and quantified: methanol, pentane, pentanal, and hexanal. Laboratory results show that total VOCs (TVOCs) concentrations for softwood (SW) were statistically (p < 0.02) higher than blended or hardwood (HW) (SW: 412 ± 25; blended: 203 ± 4; HW: 99 ± 8, ppb). The emission rate from HW was the fastest, followed by blended and SW, respectively. Emissions rates were found to range from 10−1 to 10−5 units, depending upon environmental factors. Field measurements resulted in airborne concentrations ranging from 67 ± 8 to 5000 ± 3000 ppb of TVOCs and 12 to 1500 ppb of aldehydes, with higher concentrations found in a basement with a large fabric bag storage unit after fresh pellet delivery and lower concentrations for aged pellets. These results suggest that large fabric bag storage units resulted in a substantial release of VOCs into the building air. Occupants of the buildings tested discussed concerns about odor and sensory irritation when new pellets were delivered. The sensory response was likely due to the aldehydes. PMID:27022205

The Politics of the Steady State

ERIC Educational Resources Information Center

Taylor, Charles

1978-01-01

A steady state society has limits pertaining to population size, non-renewable resources, and production which emits heat or substances into soil, water, or the atmosphere. Respecting these limits means renouncing exponential quantitative growth and accepting a universally available consumption standard. (SW)

Instabilities in Englert-type supergravity solutions

NASA Astrophysics Data System (ADS)

Page, Don N.; Pope, C. N.

1984-09-01

We show that all eleven-dimensional Englert-type supergravity solutions (in which the four-index field has internal components) constructed from internal spaces M7 having two or more Killing spinors, are unstable. Permanent address: Blackett Laboratory, Imperial College, London SW7 2BZ, United Kingdom.

Bias field tunable magnetic configuration and magnetization dynamics in Ni80Fe20 nano-cross structures with varying arm length

NASA Astrophysics Data System (ADS)

Adhikari, K.; Choudhury, S.; Mandal, R.; Barman, S.; Otani, Y.; Barman, A.

2017-01-01

Ferromagnetic nano-cross structures promise exotic static magnetic configurations and very rich and tunable magnetization dynamics leading towards potential applications in magnetic logic and communication devices. Here, we report an experimental study of external magnetic field tunable static magnetic configurations and magnetization dynamics in Ni80Fe20 nano-cross structures with varying arm lengths (L). Broadband ferromagnetic resonance measurements showed a strong variation in the number of spin-wave (SW) modes and mode frequencies (f) with bias field magnitude (H). Simulated static magnetic configurations and SW mode profiles explain the rich variation of the SW spectra, including mode softening, mode crossover, mode splitting, and mode merging. Such variation of SW spectra is further modified by the size of the nano-cross. Remarkably, with decreasing arm length of nano-cross structures, the onion magnetization ground state becomes more stable. Calculated magnetostatic field distributions support the above observations and revealed the non-collective nature of the dynamics in closely packed nano-cross structures. The latter is useful for their possible applications in magnetic storage and memory devices.

Structural mapping of Chikotra River basin in the Deccan Volcanic Province of Maharashtra, India from ground magnetic data

NASA Astrophysics Data System (ADS)

Anand, S. P.; Erram, Vinit C.; Patil, J. D.; Pawar, N. J.; Gupta, Gautam; Suryavanshi, R. A.

2016-03-01

Ground magnetic data collected over Chikotra River in the peripheral region of Deccan Volcanic Province (DVP) of Maharashtra located in Kolhapur district was analysed to throw light on the structural pattern and distribution of magnetic sources within the basin. In order to isolate the magnetic anomalies showing varying trend and amplitude, several transformation operations including wavelength filtering, and upward continuation has been carried out on the reduced to pole anomaly map. Qualitative interpretation of these products help identify the distribution of magnetic sources, viz., the Deccan basalts, dolerite intrusives and older greenstone and schist belts in the subsurface. Present study suggests that the Chikotra basin is composed of three structural units; a NE-SW unit superposed on deeper NW-SE unit with randomly distributed trap flows on the surface. One of the major outcome of the present study is the delineation of almost 900-m thick Proterozoic Kaladgi sediments below the Deccan trap flows. The NE-SW magnetic sources may probably represent intrusives into the Kaladgi sediments, while the deeper NW-SE trends are interpreted as the northward extension of the Dharwars, underneath the Deccan lava flows, that forms the basement for the deposition of Kaladgi sediments.

[Overexpression of N-myc downstream regulated gene 2 (NDRG2) inhibits proliferation, migration and promotes apoptosis in SW480 rectal cancer cells].

PubMed

Li, Zhiqiang; Sun, Yang; Wan, Hongxing; Chai, Fang

2017-01-01

Objective To investigate the role of N-myc downstream regulated gene 2 (NDRG2) gene in the proliferation, migration and apoptosis of rectal cancer cells. Methods Human rectal cancer SW480 cells were cultured and transfected with pCDNA3.1-NDRG2 and empty vector (SW480-Ve). SW480 cells were set as a control group. Cell proliferation was detected in SW480 cells, SW480-Ve cells and SW480-NDRG2 cells by MTT assay; cell migration distance in the three groups at 24, 48, 72 hours was tested by wound healing assay; apoptosis rate was determined in the three groups at 48 hours by flow cytometry; the expressions of Bax, caspase-3, Bcl-2 proteins in the three groups were examined by Western blotting. Results After the cells were cultured for 7 days, cell survival rate in SW480-NDRG2 group was significantly lower than that in SW480 cells and SW480-Ve cells; the cell survival rate decreased gradually with the prolongation of the culture time; and it had no significant difference between SW480-Ve group and SW480 group. Cell migration distance in SW480-NDRG2 group was significantly lower than that in SW480-Ve cells and SW480 cells, and it had also no significant difference between SW480-Ve cells and SW480 cells. The apoptosis rate in SW480-NDRG2 group was significantly higher than that in SW480 group and SW480-Ve group, and SW480 cells and SW480-Ve cells had no significant difference in the rate. The expressions of Bax and caspase-3 proteins in SW480-NDRG2 group were significantly higher than those in SW480 cells and SW480-Ve cells; Bcl-2 protein expression was significantly lower in SW480-NDRG2 group than in SW480 cells and SW480-Ve cells; and the expressions of Bax, caspase-3 and Bcl-2 proteins were not significantly different between SW480 cells and SW480-Ve cells. Conclusion Overexpression of NDRG2 can inhibit the proliferation, reduce cell migration, and promote cell apoptosis by regulating the expressions of Bcl-2, Bax and caspase-3 proteins in SW480 cells.

76 FR 25683 - State Energy Advisory Board (STEAB); Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

... DEPARTMENT OF ENERGY Energy Efficiency and Renewable Energy State Energy Advisory Board (STEAB); Meeting AGENCY: Energy Efficiency and Renewable Energy, Department of Energy. ACTION: Notice of Open... Energy Efficiency and Renewable Energy, 1000 Independence Avenue, SW., Washington DC 20585; or e-mail...

Stress states in the Zagros fold-and-thrust belt from passive margin to collisional tectonic setting

NASA Astrophysics Data System (ADS)

Navabpour, Payman; Barrier, Eric

2012-12-01

The present-day Zagros fold-and-thrust belt of SW-Iran corresponds to the former Arabian passive continental margin of the southern Neo-Tethyan basin since the Permian-Triassic rifting, undergoing later collisional deformation in mid-late Cenozoic times. In this paper an overview of brittle tectonics and palaeostress reconstructions of the Zagros fold-and-thrust belt is presented, based on direct stress tensor inversion of fault slip data. The results indicate that, during the Neo-Tethyan oceanic opening, an extensional tectonic regime affectedthe sedimentary cover in Triassic-Jurassic times with an approximately N-S trend of the σ3 axis, oblique to the margin, which was followed by some local changes to a NE-SW trend during Jurassic-Cretaceous times. The stress state significantly changed to thrust setting, with a NE-SW trend of the σ1 axis, and a compressional tectonic regime prevailed during the continental collision and folding of the sedimentary cover in Oligocene-Miocene times. This compression was then followed by a strike-slip stress state with an approximately N-S trend of the σ1 axis, oblique to the belt, during inversion of the inherited extensional basement structures in Pliocene-Recent times. The brittle tectonic reconstructions, therefore, highlighted major changes of the stress state in conjunction with transitions between thin- and thick-skinned structures during different extensional and compressional stages of continental deformation within the oblique divergent and convergent settings, respectively.

Structure built for Merrimack Mill at 11 North Broad Place, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Structure built for Merrimack Mill at 11 North Broad Place, SW, originally for use at the first mill village school. It has been modified into a three-unit dwelling - 11 North Broad Place, Southwest (House), 11 North Broad Place, Southwest, Huntsville, Madison County, AL

Past seawater experience enhances seawater adaptability in medaka, Oryzias latipes.

PubMed

Miyanishi, Hiroshi; Inokuchi, Mayu; Nobata, Shigenori; Kaneko, Toyoji

2016-01-01

During the course of evolution, fishes have acquired adaptability to various salinity environments, and acquirement of seawater (SW) adaptability has played important roles in fish evolution and diversity. However, little is known about how saline environments influence the acquirement of SW adaptability. The Japanese medaka Oryzias latipes is a euryhaline species that usually inhabits freshwater (FW), but is also adaptable to full-strength SW when transferred through diluted SW. In the present study, we examined how past SW experience affects hyposmoregulatory ability in Japanese medaka. For the preparation of SW-experienced fish, FW medaka were acclimated to SW after pre-acclimation to 1/2 SW, and the SW-acclimated fish were transferred back to FW. The SW-experienced fish and control FW fish (SW-inexperienced fish) were transferred directly to SW. Whereas control FW fish did not survive direct transfer to SW, 1/4 of SW-experienced fish adapted successfully to SW. Although there were no significant differences in blood osmolality and plasma Na(+) and Cl(-) concentrations between SW-experienced and control FW medaka in FW, increments in these parameters following SW transfer were lower in SW-experienced fish than in control FW fish. The gene expression of SW-type Na(+), K(+)-ATPase (NKA) in the gills of SW-experienced medaka increased more quickly after direct SW transfer compared with the expression in control FW fish. Prior to SW transfer, the density of NKA-immunoreactive ionocytes in the gills was higher in SW-experienced fish than in control FW fish. Ionocytes expressing CFTR Cl(-) channel at the apical membrane and those forming multicellular complexes, both of which were characteristic of SW-type ionocytes, were also increased in SW-experienced fish. These results indicate that past SW experience enhances the capacity of Na(+) and Cl(-) secretion in ionocytes and thus hypoosmoregulatory ability of Japanese medaka, suggesting the presence of epigenetic mechanisms involved in seawater adaptation.

sw-SVM: sensor weighting support vector machines for EEG-based brain-computer interfaces.

PubMed

Jrad, N; Congedo, M; Phlypo, R; Rousseau, S; Flamary, R; Yger, F; Rakotomamonjy, A

2011-10-01

In many machine learning applications, like brain-computer interfaces (BCI), high-dimensional sensor array data are available. Sensor measurements are often highly correlated and signal-to-noise ratio is not homogeneously spread across sensors. Thus, collected data are highly variable and discrimination tasks are challenging. In this work, we focus on sensor weighting as an efficient tool to improve the classification procedure. We present an approach integrating sensor weighting in the classification framework. Sensor weights are considered as hyper-parameters to be learned by a support vector machine (SVM). The resulting sensor weighting SVM (sw-SVM) is designed to satisfy a margin criterion, that is, the generalization error. Experimental studies on two data sets are presented, a P300 data set and an error-related potential (ErrP) data set. For the P300 data set (BCI competition III), for which a large number of trials is available, the sw-SVM proves to perform equivalently with respect to the ensemble SVM strategy that won the competition. For the ErrP data set, for which a small number of trials are available, the sw-SVM shows superior performances as compared to three state-of-the art approaches. Results suggest that the sw-SVM promises to be useful in event-related potentials classification, even with a small number of training trials.

An Intensive Cultural Resources Survey and National Register Evaluation of Archaeological Sites at the Proposed River Ranch Resort in Lyman County, South Dakota

DTIC Science & Technology

1990-02-01

34 a few minuscule pottery sherds, bone fragments and stone chips eroding from the bank". The legal location was given as SW 1/4, SW 1/4, Section 4...than that stated in the 1984 survey report. The artifacts noted by Mallory included lithic material, bone fragments and pottery fragments. These are... Bone Six bones or bone fragments were found in this level, and most of these appeared to be identifiable elements, probably from birds. No attempt was

Strain distribution across a partially molten middle crust: Insights from the AMS mapping of the Carlos Chagas Anatexite, Araçuaí belt (East Brazil)

NASA Astrophysics Data System (ADS)

Cavalcante, Geane C. G.; Egydio-Silva, Marcos; Vauchez, Alain; Camps, Pierre; Oliveira, Eurídice

2013-10-01

The easternmost part of the Neoproterozoic Araçuaí belt comprises an anatectic domain that involves anatexites (the Carlos Chagas unit), leucogranites and migmatitic granulites that display a well-developed fabric. Microstructural observations support that the deformation occurred in the magmatic to submagmatic state. Structural mapping integrating field and anisotropy of magnetic susceptibility (AMS) revealed a complex, 3D structure. The northern domain displays gently dipping foliations bearing a NW-trending lineation, southward, the lineation trend progressively rotates to EW then SW and the foliation is gently folded. The eastern domain displays E-W and NE-SW trending foliations with moderate to steeply dips bearing a dominantly NS trending lineation. Magnetic mineralogy investigation suggests biotite as the main carrier of the magnetic susceptibility in the anatexites and ferromagnetic minerals in the granulites. Crystallographic preferred orientation (CPO) measurements using the electron backscatter diffraction (EBSD) technique suggest that the magnetic fabric comes from the crystalline anisotropy of biotite and feldspar grains, especially. The delineation of several structural domains with contrasted flow fabric suggests a 3D flow field involving westward thrusting orthogonal to the belt, northwestward orogen-oblique escape tectonics and NS orogen-parallel flow. This complex deformation pattern may be due to interplay of collision-driven and gravity-driven deformations.

Kinky thresholds revisited: opportunity costs differ in the NE and SW quadrants.

PubMed

Eckermann, Simon

2015-02-01

Historically, a kinked threshold line on the cost-effectiveness plane at the origin was suggested due to differences in willingness to pay (WTP) for health gain with trade-offs in the north-east (NE) quadrant versus willingness to accept (WTA) cost reductions for health loss with trade-offs in the south-west (SW) quadrant. Empirically, WTA is greater than WTP for equivalent units of health, a finding supported by loss aversion under prospect theory. More recently, appropriate threshold values for health effects have been shown to require an endogenous consideration of the opportunity cost of alternative actions in budget-constrained health systems, but also allocative and displacement inefficiency observed in health system practice. Allocative and displacement inefficiency arise in health systems where the least cost-effective program in contraction has a higher incremental cost-effectiveness ratio (ICER = m) than the most cost-effective program in expansion (ICER = n) and displaced services (ICER = d), respectively. The health shadow price derived by Pekarsky, [Formula: see text] reflects the opportunity cost of best alternative adoption and financing actions in reimbursing new technology with expected incremental costs and net effect allowing for allocative (n < m), and displacement, inefficiency (d < m). This provides an appropriate threshold value for the NE quadrant. In this paper, I show that for trade-offs in the SW quadrant, where new strategies have lower expected net cost while lower expected net effect than current practice, the opportunity cost is contraction of the least cost-effective program, with threshold ICER m. That is, in the SW quadrant, the cost reduction per unit of decreased effect should be compared with the appropriate opportunity cost, best alternative generation of funding. Consequently, appropriate consideration of opportunity cost produces a kink in the threshold at the origin, with the health shadow price in the NE quadrant and ICER of the least cost-effective program in contraction (m) in the SW quadrant having the same general shape as that previously suggested by WTP versus WTA. The extent of this kink depends on the degree of allocative and displacement inefficiency, with no kink in the threshold line strictly only appropriate with complete allocative and displacement efficiency, that is n = d = m.

Toward a transport-based analysis of nutrient spiraling and uptake in streams

USGS Publications Warehouse

Runkel, Robert L.

2007-01-01

Nutrient addition experiments are designed to study the cycling of nutrients in stream ecosystems where hydrologic and nonhydrologic processes determine nutrient fate. Because of the importance of hydrologic processes in stream ecosystems, a conceptual model known as nutrient spiraling is frequently employed. A central part of the nutrient spiraling approach is the determination of uptake length (SW), the average distance traveled by dissolved nutrients in the water column before uptake. Although the nutrient spiraling concept has been an invaluable tool in stream ecology, the current practice of estimating uptake length from steady-state nutrient data using linear regression (called here the "SW approach") presents a number of limitations. These limitations are identified by comparing the exponential SW equation with analytical solutions of a stream solute transport model. This comparison indicates that (1) SW, is an aggregate measure of uptake that does not distinguish between main channel and storage zone processes, (2) SW, is an integrated measure of numerous hydrologie and nonhydrologic processes-this process integration may lead to difficulties in interpretation when comparing estimates of SW, and (3) estimates of uptake velocity and areal uptake rate (Vf and U) based on S W, are not independent of system hydrology. Given these findings, a transport-based approach to nutrient spiraling is presented for steady-state and time-series data sets. The transport-based approach for time-series data sets is suggested for future research on nutrient uptake as it provides a number of benefits, including the ability to (1) separately quantify main channel and storage zone uptake, (2) quantify specific hydrologic and nonhydrologic processes using various model parameters (process separation), (3) estimate uptake velocities and areal uptake rates that are independent of hydrologic effects, and (4) use short-term, non-plateau nutrient additions such that the effects of regeneration and mineralization are minimized. In summary, the transport-based, time-series approach provides a means of estimating traditional measures of nutrient uptake (SW, V?? U) while providing additional information on the location and magnitude of uptake (main channel versus storage zone). Application of the transport-based approach to time-series data from Green Creek, Antarctica, indicates that the bulk of nitrate uptake (???74% to 100%) occurred within the main channel where benthic uptake by algal mats is a likely process. Substantial uptake (???26%) also occurred in the storage zone of one reach, where uptake is attributed to the microbial community.

Photometry of the SW Sextantis-type nova-like BH Lyncis in high state

NASA Astrophysics Data System (ADS)

Stanishev, V.; Kraicheva, Z.; Genkov, V.

2006-08-01

Aims.We present a photometric study of the deeply eclipsing SW Sex-type nova-like cataclysmic variable star BH Lyn. Methods: .Time-resolved V-band CCD photometry was obtained for seven nights between 1999 and 2004. Results: .We determined 11 new eclipse timings of BH Lyn and derived a refined orbital ephemeris with an orbital period of 0.155875577(14) °. During the observations, BH Lyn was in high-state with V≃15.5 mag. The star presents ~1.5 mag deep eclipses with mean full-width at half-flux of 0.0683(±0.0054)P_orb. The eclipse shape is highly variable, even changing form cycle to cycle. This is most likely due to accretion disc surface brightness distribution variations, most probably caused by strong flickering. Time-dependent accretion disc self-occultation or variations of the hot spot(s) intensity are also possible explanations. Negative superhumps with period of ˜0.145 ° are detected in two long runs in 2000. A possible connection between SW Sex and negative superhump phenomena through the presence of tilted accretion disc is discussed, and a way to observationally test this is suggested.

75 FR 12748 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

... Line (LA), Inc., 470 Cloverleaf Drive, Unit A&B, Baldwin Park, CA 91706, Officers: Wai (aka Winson) M... Shipping & Logistics, LLC, 10651 SW. 108 Avenue, 3A, Miami, FL 33176, Officers: Lorenzo A. Macias... Individual), Zhenfen Wu, Chairman. Qingfeng Wang dba Global Intertrans Logistics, 200 East Norwood Place, San...

Production, purification and characterization of an exo-polygalacturonase from Penicillium janthinellum sw09.

PubMed

Ma, Yuping; Sun, Siwen; Hao, Hui; Xu, Chunping

2016-01-01

A soil isolate, Penicillium janthinellum sw09 has been found to produce significant amounts of an extracellular pectinase subsequently characterized as exo-polygalacturonase (exo-PG). By optimizing growth conditions, P. janthinellum sw09 produced high amount of exo-PG (16.54 units/mL). The crude enzyme was purified by gel filtration chromatography and two exo-PG activity peaks (designated as PGI and PGII) were revealed. On SDS-PAGE analysis, purified PGII using DEAE-Sepharose FF column, was found to be a single band with a molecular mass of 66.2 kDa. The purified PGII exhibited maximal activity at the temperature of 45 oC and pH 5.0. The stability profiles show that PGII is more stable in the pH range of 4.0-8.0 and below 60 oC. The Km and Vmax for the enzyme was 1.74 mg/mL and 18.08 μmol/ (mL•min), respectively. Due to this enzymatic characterization, this pectinase is an attractive candidate for applications in degradation of pectin.

Improved prediction of octanol-water partition coefficients from liquid-solute water solubilities and molar volumes

USGS Publications Warehouse

Chiou, C.T.; Schmedding, D.W.; Manes, M.

2005-01-01

A volume-fraction-based solvent-water partition model for dilute solutes, in which the partition coefficient shows a dependence on solute molar volume (V??), is adapted to predict the octanol-water partition coefficient (K ow) from the liquid or supercooled-liquid solute water solubility (Sw), or vice versa. The established correlation is tested for a wide range of industrial compounds and pesticides (e.g., halogenated aliphatic hydrocarbons, alkylbenzenes, halogenated benzenes, ethers, esters, PAHs, PCBs, organochlorines, organophosphates, carbamates, and amidesureas-triazines), which comprise a total of 215 test compounds spanning about 10 orders of magnitude in Sw and 8.5 orders of magnitude in Kow. Except for phenols and alcohols, which require special considerations of the Kow data, the correlation predicts the Kow within 0.1 log units for most compounds, much independent of the compound type or the magnitude in K ow. With reliable Sw and V data for compounds of interest, the correlation provides an effective means for either predicting the unavailable log Kow values or verifying the reliability of the reported log Kow data. ?? 2005 American Chemical Society.

Changes in bacterial composition of biofilm in a metropolitan drinking water distribution system.

PubMed

Revetta, R P; Gomez-Alvarez, V; Gerke, T L; Santo Domingo, J W; Ashbolt, N J

2016-07-01

This study examined the development of bacterial biofilms within a metropolitan distribution system. The distribution system is fed with different source water (i.e. groundwater, GW and surface water, SW) and undergoes different treatment processes in separate facilities. The biofilm community was characterized using 16S rRNA gene clone libraries and functional potential analysis, generated from total DNA extracted from coupons in biofilm annular reactors fed with onsite drinking water for up to 18 months. Differences in the bacterial community structure were observed between GW and SW. Representatives that explained the dissimilarity were associated with the classes Betaproteobacteria, Alphaproteobacteria, Actinobacteria, Gammaproteobacteria and Firmicutes. After 9 months the biofilm bacterial community from both GW and SW were dominated by Mycobacterium species. The distribution of the dominant operational taxonomic unit (OTU) (Mycobacterium) positively correlated with the drinking water distribution system (DWDS) temperature. In this study, the biofilm community structure observed between GW and SW were dissimilar, while communities from different locations receiving SW did not show significant differences. The results suggest that source water and/or the water quality shaped by their respective treatment processes may play an important role in shaping the bacterial communities in the distribution system. In addition, several bacterial groups were present in all samples, suggesting that they are an integral part of the core microbiota of this DWDS. These results provide an ecological insight into biofilm bacterial structure in chlorine-treated drinking water influenced by different water sources and their respective treatment processes. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

Large-scale structures of solar wind and dynamics of parameters in them

NASA Astrophysics Data System (ADS)

Yermolaev, Yuri; Lodkina, Irina; Yermolaev, Michael

2017-04-01

On the basis of OMNI dataset and our catalog of large-scale solar wind (SW) phenomena (see web-site ftp://ftp.iki.rssi.ru/pub/omni/ and paper by Yermolaev et al., 2009) we study temporal profile of interplanetary and magnetospheric parameters in following SW phenomena: interplanetary manifestation of coronal mass ejection (ICME) including magnetic cloud (MC) and Ejecta, Sheath—compression region before ICME and corotating interaction region (CIR)—compression region before high-speed stream (HSS) of solar wind. To take into account a possible influence of other SW types, following sequences of phenomena, which include all typical sequences of non-stationary SW events, are analyzed: (1) SW/ CIR/ SW, (2) SW/ IS/ CIR/ SW, (3) SW/ Ejecta/ SW, (4) SW/ Sheath/Ejecta/ SW, (5) SW/ IS/ Sheath/ Ejecta/ SW, (6) SW/ MC/ SW, (7) SW/Sheath/ MC/ SW, (8) SW/ IS/ Sheath/ MC/ SW (where SW is undisturbed solar wind, and IS is interplanetary shock) (Yermolaev et al., 2015) using the method of double superposed epoch analysis for large numbers of events (Yermolaev et al., 2010). Similarities and distinctions of different SW phenomena depending on neighboring SW types and their geoeffectiveness are discussed. The work was supported by the Russian Science Foundation, projects 16-12-10062. References: Yermolaev, Yu. I., N. S. Nikolaeva, I. G. Lodkina, and M. Yu. Yermolaev (2009), Catalog of Large-Scale Solar Wind Phenomena during 1976-2000, Cosmic Research, , Vol. 47, No. 2, pp. 81-94. Yermolaev, Y. I., N. S. Nikolaeva, I. G. Lodkina, and M. Y. Yermolaev (2010), Specific interplanetary conditions for CIR-induced, Sheath-induced, and ICME-induced geomagnetic storms obtained by double superposed epoch analysis, Ann. Geophys., 28, pp. 2177-2186. Yermolaev, Yu. I., I. G. Lodkina, N. S. Nikolaeva, and M. Yu. Yermolaev (2015), Dynamics of large-scale solar wind streams obtained by the double superposed epoch analysis, J. Geophys. Res. Space Physics, 120, doi:10.1002/2015JA021274.

Assessment of long-term WRF–CMAQ simulations for understanding direct aerosol effects on radiation "brightening" in the United States

DOE PAGES

Gan, C.-M.; Pleim, J.; Mathur, R.; ...

2015-11-03

Long-term simulations with the coupled WRF–CMAQ (Weather Research and Forecasting–Community Multi-scale Air Quality) model have been conducted to systematically investigate the changes in anthropogenic emissions of SO 2 and NO x over the past 16 years (1995–2010) across the United States (US), their impacts on anthropogenic aerosol loading over North America, and subsequent impacts on regional radiation budgets. In particular, this study attempts to determine the consequences of the changes in tropospheric aerosol burden arising from substantial reductions in emissions of SO 2 and NO x associated with control measures under the Clean Air Act (CAA) especially on trends inmore » solar radiation. Extensive analyses conducted by Gan et al. (2014a) utilizing observations (e.g., SURFRAD, CASTNET, IMPROVE, and ARM) over the past 16 years (1995–2010) indicate a shortwave (SW) radiation (both all-sky and clear-sky) "brightening" in the US. The relationship of the radiation brightening trend with decreases in the aerosol burden is less apparent in the western US. One of the main reasons for this is that the emission controls under the CAA were aimed primarily at reducing pollutants in areas violating national air quality standards, most of which were located in the eastern US, while the relatively less populated areas in the western US were less polluted at the beginning of this study period. Comparisons of model results with observations of aerosol optical depth (AOD), aerosol concentration, and radiation demonstrate that the coupled WRF–CMAQ model is capable of replicating the trends well even though it tends to underestimate the AOD. In particular, the sulfate concentration predictions were well matched with the observations. The discrepancies found in the clear-sky diffuse SW radiation are likely due to several factors such as the potential increase of ice particles associated with increasing air traffic, the definition of "clear-sky" in the radiation retrieval methodology, and aerosol semi-direct and/or indirect effects which cannot be readily isolated from the observed data.« less

Assessment of multi-decadal WRF-CMAQ simulations for understanding direct aerosol effects on radiation "brightening" in the United States

DOE PAGES

Gan, C.-M.; Pleim, J.; Mathur, R.; ...

2015-07-01

Multi-decadal simulations with the coupled WRF-CMAQ model have been conducted to systematically investigate the changes in anthropogenic emissions of SO 2 and NO x over the past 21 years (1990–2010) across the United States (US), their impacts on anthropogenic aerosol loading over North America, and subsequent impacts on regional radiation budgets. In particular, this study attempts to determine the consequences of the changes in tropospheric aerosol burden arising from substantial reductions in emissions of SO 2 and NO x associated with control measures under the Clean Air Act (CAA) especially on trends in solar radiation. Extensive analyses conducted by Ganmore » et al. (2014) utilizing observations (e.g. SURFRAD, CASTNET, IMPROVE and ARM) over the past 16 years (1995–2010) indicate a shortwave (SW) radiation (both all-sky and clear-sky) "brightening" in the US. The relationship of the radiation brightening trend with decreases in the aerosol burden is less apparent in the western US. One of the main reasons for this is that the emission controls under the CAA were aimed primarily at reducing pollutants in areas violating national air quality standards, most of which were located in the eastern US while the relatively less populated areas in the western US were less polluted at the beginning of this study period. Comparisons of model results with observations of aerosol optical depth (AOD), aerosol concentration, and radiation demonstrate that the coupled WRF-CMAQ model is capable of replicating the trends well even through it tends to underestimate the AOD. In particular, the sulfate concentration predictions were well matched with the observations. The discrenpancies found in the clear-sky diffuse SW radiation are likely due to several factors such as potential increase of ice particles associated with increasing air traffic, the definition of "clear-sky" in the radiation retrieval methodology and aerosol semi-direct and/or indirect effects which cannot be readily isolated from the observed data.« less

Assessment of multi-decadal WRF-CMAQ simulations for understanding direct aerosol effects on radiation "brightening" in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gan, C.-M.; Pleim, J.; Mathur, R.

Multi-decadal simulations with the coupled WRF-CMAQ model have been conducted to systematically investigate the changes in anthropogenic emissions of SO 2 and NO x over the past 21 years (1990–2010) across the United States (US), their impacts on anthropogenic aerosol loading over North America, and subsequent impacts on regional radiation budgets. In particular, this study attempts to determine the consequences of the changes in tropospheric aerosol burden arising from substantial reductions in emissions of SO 2 and NO x associated with control measures under the Clean Air Act (CAA) especially on trends in solar radiation. Extensive analyses conducted by Ganmore » et al. (2014) utilizing observations (e.g. SURFRAD, CASTNET, IMPROVE and ARM) over the past 16 years (1995–2010) indicate a shortwave (SW) radiation (both all-sky and clear-sky) "brightening" in the US. The relationship of the radiation brightening trend with decreases in the aerosol burden is less apparent in the western US. One of the main reasons for this is that the emission controls under the CAA were aimed primarily at reducing pollutants in areas violating national air quality standards, most of which were located in the eastern US while the relatively less populated areas in the western US were less polluted at the beginning of this study period. Comparisons of model results with observations of aerosol optical depth (AOD), aerosol concentration, and radiation demonstrate that the coupled WRF-CMAQ model is capable of replicating the trends well even through it tends to underestimate the AOD. In particular, the sulfate concentration predictions were well matched with the observations. The discrenpancies found in the clear-sky diffuse SW radiation are likely due to several factors such as potential increase of ice particles associated with increasing air traffic, the definition of "clear-sky" in the radiation retrieval methodology and aerosol semi-direct and/or indirect effects which cannot be readily isolated from the observed data.« less

Assessment of long-term WRF–CMAQ simulations for understanding direct aerosol effects on radiation "brightening" in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gan, C.-M.; Pleim, J.; Mathur, R.

Long-term simulations with the coupled WRF–CMAQ (Weather Research and Forecasting–Community Multi-scale Air Quality) model have been conducted to systematically investigate the changes in anthropogenic emissions of SO 2 and NO x over the past 16 years (1995–2010) across the United States (US), their impacts on anthropogenic aerosol loading over North America, and subsequent impacts on regional radiation budgets. In particular, this study attempts to determine the consequences of the changes in tropospheric aerosol burden arising from substantial reductions in emissions of SO 2 and NO x associated with control measures under the Clean Air Act (CAA) especially on trends inmore » solar radiation. Extensive analyses conducted by Gan et al. (2014a) utilizing observations (e.g., SURFRAD, CASTNET, IMPROVE, and ARM) over the past 16 years (1995–2010) indicate a shortwave (SW) radiation (both all-sky and clear-sky) "brightening" in the US. The relationship of the radiation brightening trend with decreases in the aerosol burden is less apparent in the western US. One of the main reasons for this is that the emission controls under the CAA were aimed primarily at reducing pollutants in areas violating national air quality standards, most of which were located in the eastern US, while the relatively less populated areas in the western US were less polluted at the beginning of this study period. Comparisons of model results with observations of aerosol optical depth (AOD), aerosol concentration, and radiation demonstrate that the coupled WRF–CMAQ model is capable of replicating the trends well even though it tends to underestimate the AOD. In particular, the sulfate concentration predictions were well matched with the observations. The discrepancies found in the clear-sky diffuse SW radiation are likely due to several factors such as the potential increase of ice particles associated with increasing air traffic, the definition of "clear-sky" in the radiation retrieval methodology, and aerosol semi-direct and/or indirect effects which cannot be readily isolated from the observed data.« less

78 FR 35149 - Addresses of Regional Offices

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-12

..., and Texas), 500 Gold Avenue SW., Room 9018 (P.O. Box 1306), Albuquerque, New Mexico 87102. (c) Midwest... 01035. (f) Mountain-Prairie Regional Office (Region 6--comprising the States of Colorado, Kansas...), Lakewood, Colorado 80228. (g) Alaska Regional Office (Region 7--comprising the State of Alaska), 1011 E...

Detection of amines with extended distyrylbenzenes by strip assays.

PubMed

Kumpf, Jan; Freudenberg, Jan; Fletcher, Katharyn; Dreuw, Andreas; Bunz, Uwe H F

2014-07-18

We herein describe the synthesis and property evaluation of three novel aldehyde-substituted pentameric phenylenevinylenes carrying branched oligo(ethylene glycol) (swallowtail, Sw) substituents. The targets were synthesized by a combination of Heck coupling and Wittig or Horner reactions of suitable precursor modules. If the pentameric phenylenevinylene carries only two of these Sw substituents, it is no longer water-soluble. When six of the Sw substituents are attached, regardless of their position, the pentameric phenylenevinylenes are well water-soluble. The dialdehydes were investigated with respect to their amine-sensing capabilities both in water as well as in the solid state, sprayed onto thin layer chromatography (TLC) plates (alox, silica gel, reversed phase silica gel). The recognition of amine vapors using the sprayed-on phenylenevinylene dialdehydes is superb and allows the identification of different amines on regular silica TLC plates via color changes, analyzed by a statistical tool, the multivariate analysis of variance (MANOVA) protocol.

Simulating the Heliosphere with Kinetic Hydrogen and Dynamic MHD Source Terms

DOE PAGES

Heerikhuisen, Jacob; Pogorelov, Nikolai; Zank, Gary

2013-04-01

The interaction between the ionized plasma of the solar wind (SW) emanating from the sun and the partially ionized plasma of the local interstellar medium (LISM) creates the heliosphere. The heliospheric interface is characterized by the tangential discontinuity known as the heliopause that separates the SW and LISM plasmas, and a termination shock on the SW side along with a possible bow shock on the LISM side. Neutral Hydrogen of interstellar origin plays a critical role in shaping the heliospheric interface, since it freely traverses the heliopause. Charge-exchange between H-atoms and plasma protons couples the ions and neutrals, but themore » mean free paths are large, resulting in non-equilibrated energetic ion and neutral components. In our model, source terms for the MHD equations are generated using a kinetic approach for hydrogen, and the key computational challenge is to resolve these sources with sufficient statistics. For steady-state simulations, statistics can accumulate over arbitrarily long time intervals. In this paper we discuss an approach for improving the statistics in time-dependent calculations, and present results from simulations of the heliosphere where the SW conditions at the inner boundary of the computation vary according to an idealized solar cycle.« less

77 FR 4799 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-31

... Technical Advisor, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287- 1644. SUPPLEMENTARY INFORMATION...

Slip Potential of Faults in the Fort Worth Basin

NASA Astrophysics Data System (ADS)

Hennings, P.; Osmond, J.; Lund Snee, J. E.; Zoback, M. D.

2017-12-01

Similar to other areas of the southcentral United States, the Fort Worth Basin of NE Texas has experienced an increase in the rate of seismicity which has been attributed to injection of waste water in deep saline aquifers. To assess the hazard of induced seismicity in the basin we have integrated new data on location and character of previously known and unknown faults, stress state, and pore pressure to produce an assessment of fault slip potential which can be used to investigate prior and ongoing earthquake sequences and for development of mitigation strategies. We have assembled data on faults in the basin from published sources, 2D and 3D seismic data, and interpretations provided from petroleum operators to yield a 3D fault model with 292 faults ranging in strike-length from 116 to 0.4 km. The faults have mostly normal geometries, all cut the disposal intervals, and most are presumed to cut into the underlying crystalline and metamorphic basement. Analysis of outcrops along the SW flank of the basin assist with geometric characterization of the fault systems. The interpretation of stress state comes from integration of wellbore image and sonic data, reservoir stimulation data, and earthquake focal mechanisms. The orientation of SHmax is generally uniform across the basin but stress style changes from being more strike-slip in the NE part of the basin to normal faulting in the SW part. Estimates of pore pressure come from a basin-scale hydrogeologic model as history-matched to injection test data. With these deterministic inputs and appropriate ranges of uncertainty we assess the conditional probability that faults in our 3D model might slip via Mohr-Coulomb reactivation in response to increases in injected-related pore pressure. A key component of the analysis is constraining the uncertainties associated with each of the principal parameters. Many of the faults in the model are interpreted to be critically-stressed within reasonable ranges of uncertainty.

Implementation of magnetic, gravity and resistivity data in identifying groundwater occurrences in El Qaa Plain area, Southern Sinai, Egypt

NASA Astrophysics Data System (ADS)

Selim, El Sayed; Abdel-Raouf, Osama; Mesalam, Mohamed

2016-10-01

El Qaa plain is one of the areas that have been proved to be promising as to its soil and groundwater resources in the southwestern part of Sinai. This study was carried out to study the lateral and vertical variations in the subsurface lithologic properties in El Qaa plain area and delineating the subsurface structure that affecting El Qaa plain depression. Gravity, magnetic data, fifty-one (51) vertical electrical sounding (Ves's) and Digital Elevation Model (DEM) map were used. Two-dimensional density modeling, analytical signal, tilt derivatives, Euler deconvolution techniques and interpretation of the resistivity data were applied on potential data. This study concluded that, El Qaa plain is a NE-SW depression confined by two normal faults and subdivided into five sedimentary units. Rock fragments and boulders derived to the plain from the surrounding highlands are the main components of the first surface unit that characterized by high resistivity values. This layer is overly another unit composed of gravelly sand with thickness ranging between 10 and 140 m. The third unit is composed mainly of sand with intercalations of clay with thickness ranging from 2 to 152 m. A Reefal limestone unit is a fourth unit interpreted from this study. The fifth unit is composed of clay. The water bearing formations in El Qaa Plain area are located principally in the second and the third layers. Finally, the depth to the basement surface ranges from 400 m to more than 1.5 km below sea level. Also, there are many minor structural trends interpreted from this study and affecting the El Qaa plain are striking in N-S, E-W and NE-SW directions.

50 CFR 2.2 - Locations of regional offices.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the States of Arizona, New Mexico, Oklahoma, and Texas), 500 Gold Avenue SW., Room 9018 (P.O. Box 1306... States of Colorado, Kansas, Montana, Nebraska, North Dakota, South Dakota, Utah and Wyoming), 134 Union Boulevard (P.O. Box 25486), Lakewood, Colorado 80228. (g) Alaska Regional Office (Region 7—comprising the...

50 CFR 2.2 - Regional offices.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the States of Arizona, New Mexico, Oklahoma, and Texas), 500 Gold Avenue SW., Room 9018 (P.O. Box 1306... States of Colorado, Kansas, Montana, Nebraska, North Dakota, South Dakota, Utah and Wyoming), 134 Union Boulevard (P.O. Box 25486), Lakewood, Colorado 80228. (g) Alaska Regional Office (Region 7—comprising the...

76 FR 80777 - Approval and Promulgation of State Plans for Designated Facilities and Pollutants; State of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-27

... Monitoring Branch, Air, Pesticides and Toxics Management Division, U.S. Environmental Protection Agency... Management Division, U.S. Environmental Protection Agency, Region 4, 61 Forsyth Street SW., Atlanta, Georgia..., Air, Pesticides and Toxics Management Division, U.S. Environmental Protection Agency, Region 4, 61...

78 FR 1209 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

..., STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644. SUPPLEMENTARY...

78 FR 44943 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-25

...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC, 20585. Phone number is (202) 287...

78 FR 6088 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-29

..., STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644. SUPPLEMENTARY...

Stability analysis of compactifications of D = 11 supergravity with SU(3) × SU(2) × U(1) symmetry

NASA Astrophysics Data System (ADS)

Page, Don N.; Pope, C. N.

1984-09-01

We show that the Mpqr Freund-Rubin compactification of eleven-dimensional supergravity is classically stable if and only if 7/2761/2 < -p/q- < 17/117(66)1/2. Permanent address: Blackett Laboratory, Imperial College, London SW7 2BZ, United Kingdom.

A Dissemination Model for New Technical Education Programs. Final Report.

ERIC Educational Resources Information Center

Hull, Daniel M.

The Technical Education Research Center-SW has conceived, tested, and refined a model for disseminating newly developed programs and materials throughout the nation. The model performed successfully in the dissemination of more than 50,000 educational units (modules) of Laser/Electro-Optics Technician (LEOT) materials during a four-year period…

78 FR 52171 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644...

77 FR 64495 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-22

... Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644. SUPPLEMENTARY INFORMATION: Purpose...

77 FR 20014 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-03

...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644...

2. OVERALL VIEW OF THE MEDICAL CENTER (ESPECIALLY BUILDING 1) ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. OVERALL VIEW OF THE MEDICAL CENTER (ESPECIALLY BUILDING 1) FROM THE 'CAMPUS' GROUNDS; LOOKING SW. (Harms) - Veterans Administration Medical Center, Old State Route 13 West, Marion, Williamson County, IL

Optimization of nisin production by Lactococcus lactis UQ2 using supplemented whey as alternative culture medium.

PubMed

González-Toledo, S Y; Domínguez-Domínguez, J; García-Almendárez, B E; Prado-Barragán, L A; Regalado-González, C

2010-08-01

Lactococcus lactis UQ2 is a nisin A-producing native strain. In the present study, the production of nisin by L. lactis UQ2 in a bioreactor using supplemented sweet whey (SW) was optimized by a statistical design of experiments and response surface methodology (RSM). In a 1st approach, a fractional factorial design (FFD) of the order 2(5-1) with 3 central points was used. The effect on nisin production of air flow, SW, soybean peptone (SP), MgSO(4)/MnSO(4) mixture, and Tween 80 was evaluated. From FFD, the most significant factors affecting nisin production were SP (P = 0.011), and SW (P = 0.037). To find optimum conditions, a central composite design (CCD) with 2 central points was used. Three factors were considered, SW (7 to 10 g/L), SP (7 to10 g/L), and small amounts of added nisin as self-inducer (NI 34.4 to 74.4 IU/L). Nisin production was expressed as international units (IU). From RSM, an optimum nisin activity of 180 IU/mL was predicted at 74.4 IU/L NI, 13.8 g/L SP, and 14.9 or 5.11 g/L SW, while confirmatory experiments showed a maximum activity of 178 +/- 5.2 IU/mL, verifying the validity of the model. The 2nd-order model showed a coefficient of determination (R(2)) of 0.828. Optimized conditions were used for constant pH fermentations, where a maximum activity of 575 +/- 17 IU/mL was achieved at pH 6.5 after 12 h. The adsorption-desorption technique was used to partially purify nisin, followed by drying. The resulting powder showed an activity of 102150 IU/g. Practical Application: Nisin production was optimized using supplemented whey as alternative culture medium, using a native L. lactis UQ2 strain. Soybean peptone, SW, and subinhibitory amounts of nisin were successfully employed to optimize nisin production by L. lactis UQ2. Dried semipurified nisin showed an activity of 102150 IU/g.

50 CFR 2.2 - Locations of regional offices.

Code of Federal Regulations, 2011 CFR

2011-10-01

...—comprising the States of Arizona, New Mexico, Oklahoma and Texas), 500 Gold Avenue, SW, Room 9018 (P.O. Box... Regional Office (Region 6—comprising the States of Colorado, Kansas, Montana, Nebraska, North Dakota, South Dakota, Utah and Wyoming), 134 Union Boulevard (P.O. Box 25486), Denver Federal Center, Denver, Colorado...

50 CFR 2.2 - Locations of regional offices.

Code of Federal Regulations, 2012 CFR

2012-10-01

...—comprising the States of Arizona, New Mexico, Oklahoma and Texas), 500 Gold Avenue, SW, Room 9018 (P.O. Box... Regional Office (Region 6—comprising the States of Colorado, Kansas, Montana, Nebraska, North Dakota, South Dakota, Utah and Wyoming), 134 Union Boulevard (P.O. Box 25486), Denver Federal Center, Denver, Colorado...

50 CFR 2.2 - Locations of regional offices.

Code of Federal Regulations, 2010 CFR

2010-10-01

...—comprising the States of Arizona, New Mexico, Oklahoma and Texas), 500 Gold Avenue, SW, Room 9018 (P.O. Box... Regional Office (Region 6—comprising the States of Colorado, Kansas, Montana, Nebraska, North Dakota, South Dakota, Utah and Wyoming), 134 Union Boulevard (P.O. Box 25486), Denver Federal Center, Denver, Colorado...

A Comparison of the Majors of Deaf and Hearing Students at California State University, Northridge

ERIC Educational Resources Information Center

Murphy, Harry J.; Jacobs, L. Ronald

1978-01-01

Academic majors (by school) are compared for deaf and hearing students registered at California State University, Northridge, for the Fall semester of 1976. A greater proportion of deaf than hearing students study liberal arts at the undergraduate level and education at the graduate level. (SW)

A Survey of State Policies on the Use of Medication in Schools.

ERIC Educational Resources Information Center

Courtnage, Lee

1982-01-01

A national survey was conducted to determine the existing legal authority of the 50 states concerning the administration and overall management of legally prescribed drugs in the school system and to delineate the major components contained in the statutes, promulgated regulations, opinions of attorneys general, and recommended guidelines. (SW)

Effects of clouds on the surface shortwave radiation at a rural inland mid-latitude site

NASA Astrophysics Data System (ADS)

Salgueiro, Vanda; Costa, Maria João; Silva, Ana Maria; Bortoli, Daniele

2016-09-01

Seven years (2003-2010) of measured shortwave (SW) irradiances were used to obtain estimates of the 10 min averaged effective cloud optical thickness (ECOT) and of the shortwave cloud radiative effect (CRESW) at the surface in a mid-latitude site (Évora - south of Portugal), and its seasonal variability is presented. The ECOT, obtained using transmittance measurements at 415 nm, was compared with the correspondent MODIS cloud optical thickness (MODIS COT) for non-precipitating water clouds and cloud fractions higher than 0.25. This comparison showed that the ECOT represents well the cloud optical thickness over the study area. The CRESW, determined for two SW broadband ranges (300-1100 nm; 285-2800 nm), was normalized (NCRESW) and related with the obtained ECOT. A logarithmic relation between NCRESW and ECOT was found for both SW ranges, presenting lower dispersion for overcast-sky situations than for partially cloudy-sky situations. The NCRESW efficiency (NCRESW per unit of ECOT) was also related with the ECOT for overcast-sky conditions. The relation found is parameterized by a power law function showing that NCRESW efficiency decreases as the ECOT increases, approaching one for ECOT values higher than about 50.

Overcoming communication challenges in integrative supportive cancer care: The integrative physician, the psycho-oncologist, and the patient.

PubMed

Ben-Arye, Eran; Shavit, Efrat; Wiental, Haya; Schiff, Elad; Agour, Olga; Samuels, Noah

2016-12-01

Complementary/integrative medicine (CIM) services are increasingly being integrated into conventional supportive cancer care, presenting a number of challenges to communication between healthcare professionals (HCPs). The purpose of the present study was to explore the impact of the communication between integrative physicians (IPs) trained in CIM and social workers (SWs) working as psycho-oncologists in the same oncology setting. We examine whether IP-SW communication correlates with the number of patient-SW sessions, as provided within the oncology department. SW-IP communication, defined as a summary of the IP consultation sent to the patient's SW, was compared to SW-patient communication, defined as the number of psycho-oncology treatment sessions. Of 344 patients referred by their oncology HCP for IP consultation, 91 were referred by an SW and 253 by an oncologist or nurse. IP-to-SW summaries were provided for 150 patients referred by a non-SW HCP (43.6%), and for 91 of SW-referred patients (26.5%). In all, 32 patients referred to the IP had no psycho-oncology interaction with an SW; 58 only one meeting; and 254 with ≥2 interactions, with 119 having >6 sessions. SW-patient interactions were greater with higher rates of IP-SW communication, for both patients referred by an SW (79.1%) and those referred by a non-SW HCP (77.3%) when compared to patients for whom no summary was provided (64.1%; p= 0.02). A greater level of IP-SW communication, measured by the provision of an IP summary to the patient's SW, was found to correlate with a higher rate of SW-patient interactions. The use of a structured two-way referral-summary between IPs and SWs has the potential to advance the SW-patient psycho-oncology interaction, within an integrative supportive cancer care setting. Copyright © 2016 Elsevier Ltd. All rights reserved.

Transition mechanism of Stone-Wales defect in armchair edge (5,5) carbon nanotube

NASA Astrophysics Data System (ADS)

Setiadi, Agung; Suprijadi

2015-04-01

We performed first principles calculations of Stone-Wales (SW) defects in armchair edge (5,5) carbon nanotube (CNT) by the density functional theory (DFT). Stone Wales (SW) defect is one kind of topological defect on the CNT. There are two kind of SW defect on the armchair edge (5,5) CNT, such as longitudinal and circumference SW defect. Barrier energy in the formation of SW defects is a good consideration to become one of parameter in controlling SW defects on the CNT. Our calculation results that a longitudinal SW defect is more stable than circumference SW defect. However, the barrier energy of circumference SW defect is lower than another one. We applied Climbing Image Nudge Elastic Band (CI-NEB) method to find minimum energy path (MEP) and barrier energy for SW defect transitions. We also found that in the case of circumference SW defect, armchair edge (5,5) CNT become semiconductor with the band gap of 0.0544 eV.

7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... paragraph (e) covers all portions of a generating plant including plant buildings, the generator step-up... States Department of Agriculture, Stop 1522, 1400 Independence Ave., SW., Washington, DC 20250-1522. The...

Working for a not-for-Profit Research and Development Organization in the Earth Sciences

NASA Astrophysics Data System (ADS)

McKague, h L

2001-12-01

The Southwest Research Institute (SwRI) is an independent not-for-profit applied engineering and physical sciences research and development organization. This means that SwRI owes no allegiance to organizations other than its clients. As a not-for-profit organization, SwRI reinvests its net income into the organization to improve, strengthen, and expand facilities and to support internal research and development projects. Located in San Antonio, Texas, on 1200 acres, SwRI employs nearly 2800 staff and occupies nearly 2,000,000 square feet of office space. Its business is about equally divided between commercial and government clients, most of whom have specific scientific and technical problems that need to be solved in a timely, cost-effective manner. Governmental clients include local, state, and federal agencies and foreign governments. Commercial clients include local, national, and international businesses. Earth science disciplines at SwRI include geology, geophysics, hydrology, geochemistry, rock mechanics, mining engineering, and natural hazard assessment. Our overall approach is to systematically examine client problems and develop solutions that may include field work, laboratory work, numerical modeling, or some combination of these approaches. This method of problem solving places a strong emphasis on interdisciplinary teamwork. The work environment at SwRI strikes a balance among the freedom to attack technically important problems, consistent support to professional development, and a strong commitment to meeting client's deadlines and goals. Real problems with real consequences are routinely solved on a tight schedule. The diversity of clients gives exposure to an extraordinarily wide range of problems. Successful employees have sound technical backgrounds, are flexible in accommodating varying clients needs, bring creativity and energy to problem solving and applications of technologies, can work on multiple tasks in parallel, and can communicate clearly with clients and other team members. Professional development is supported through encouragement of continuing education, as well as publication and presentation of professional work. An overview of the earth science staff and work at SwRI can be found at http://www.swri.edu/4org/d20/d20home.htm

Spin wave mode coexistence on the nanoscale: A consequence of the Oersted field induced asymmetric energy landscape

NASA Astrophysics Data System (ADS)

Dumas, Randy

2014-03-01

The emerging field of magnonics relies on the systematic generation, manipulation, and detection of spin waves (SWs). Nanocontact spin torque oscillators (NC-STOs) provide an ideal platform to study spin transfer torque induced SW emission. In analogy to two species competing for the same food supply it has been argued that only one SW mode can survive in the steady state. However, as evidenced in many experiments clear signatures of mode-hopping are often observed. Here, we present a third possibility, namely that under the correct experimental conditions, mode coexistencecan be realized in NC-STOs. Micromagnetic simulations reveal that the SW modes are spatially separated under the NC. Mode coexistence is facilitated by the local field asymmetries induced by the spatially inhomogeneous Oersted field in the vicinity of the NC and further promoted by SW localization. Finally, both simulation and experiment reveal a weak low frequency signal exactly at the difference of the mode frequencies, consistent with inter-modulation of two coexistent modes. The Swedish Research Council, The Swedish Foundation for Strategic Research, and the Knut and Alice Wallenberg Foundation are acknowledged. ANL is a US DOE Science Laboratory operated under contract no. DE-AC02-06CH11357 by UChicago Argonne, LLC.

Developing a particle tracking surrogate model to improve inversion of ground water - Surface water models

NASA Astrophysics Data System (ADS)

Cousquer, Yohann; Pryet, Alexandre; Atteia, Olivier; Ferré, Ty P. A.; Delbart, Célestine; Valois, Rémi; Dupuy, Alain

2018-03-01

The inverse problem of groundwater models is often ill-posed and model parameters are likely to be poorly constrained. Identifiability is improved if diverse data types are used for parameter estimation. However, some models, including detailed solute transport models, are further limited by prohibitive computation times. This often precludes the use of concentration data for parameter estimation, even if those data are available. In the case of surface water-groundwater (SW-GW) models, concentration data can provide SW-GW mixing ratios, which efficiently constrain the estimate of exchange flow, but are rarely used. We propose to reduce computational limits by simulating SW-GW exchange at a sink (well or drain) based on particle tracking under steady state flow conditions. Particle tracking is used to simulate advective transport. A comparison between the particle tracking surrogate model and an advective-dispersive model shows that dispersion can often be neglected when the mixing ratio is computed for a sink, allowing for use of the particle tracking surrogate model. The surrogate model was implemented to solve the inverse problem for a real SW-GW transport problem with heads and concentrations combined in a weighted hybrid objective function. The resulting inversion showed markedly reduced uncertainty in the transmissivity field compared to calibration on head data alone.

Method And Apparatus For Examining A Tissue Using The Spectral Wing Emission Therefrom Induced By Visible To Infrared Photoexcitation.

DOEpatents

Alfano, Robert R.; Demos, Stavros G.; Zhang, Gang

2003-12-16

Method and an apparatus for examining a tissue using the spectral wing emission therefrom induced by visible to infrared photoexcitation. In one aspect, the method is used to characterize the condition of a tissue sample and comprises the steps of (a) photoexciting the tissue sample with substantially monochromatic light having a wavelength of at least 600 nm; and (b) using the resultant far red and near infrared spectral wing emission (SW) emitted from the tissue sample to characterize the condition of the tissue sample. In one embodiment, the substantially monochromatic photoexciting light is a continuous beam of light, and the resultant steady-state far red and near infrared SW emission from the tissue sample is used to characterize the condition of the tissue sample. In another embodiment, the substantially monochromatic photoexciting light is a light pulse, and the resultant time-resolved far red and near infrared SW emission emitted from the tissue sample is used to characterize the condition of the tissue sample. In still another embodiment, the substantially monochromatic photoexciting light is a polarized light pulse, and the parallel and perpendicular components of the resultant polarized time-resolved SW emission emitted from the tissue sample are used to characterize the condition of the tissue sample.

A Theoretical Study of Landing Mat Behavior

DTIC Science & Technology

1969-07-01

deflection pattern was pronouncedly unsy’metrical. The soil properties rcported, which were use., lor the meat- scil moLe!, r’ay represent a strongjer sub...OF THE AVERAGE WATER CONTENT (PERCENT) C AND THE AVERAGE DRY UNIT WEIGHT OF THE TOP 18 INCHES OF SCIL . C LtSW * AVERAGE C.BR. VALUE FOR THE TOP IB

78 FR 1 - Soybean Promotion and Research: Amend the Order To Adjust Representation on the United Soybean Board

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... process. DATES: Effective Date: January 3, 2012. FOR FURTHER INFORMATION CONTACT: Emily DeBord..., Room 2628-S, STOP 0249, 1400 Independence Avenue SW., Washington, DC 20250-0249; Telephone 202/690-2611; Fax 202/720- 1125; or email to Emily[email protected] . SUPPLEMENTARY INFORMATION: Executive Order...

40 CFR 75.6 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., phone: 610-832-9585, http://www.astm.org/DIGITAL_LIBRARY/index.shtml. (1) ASTM D129-00, Standard Test... Information Reference Unit of the U.S. EPA, 401 M St., SW., Washington, DC and at the Library (MD-35), U.S... D4052-96 (Reapproved 2002), Standard Test Method for Density and Relative Density of Liquids by Digital...

40 CFR 75.6 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., phone: 610-832-9585, http://www.astm.org/DIGITAL_LIBRARY/index.shtml. (1) ASTM D129-00, Standard Test... Information Reference Unit of the U.S. EPA, 401 M St., SW., Washington, DC and at the Library (MD-35), U.S... D4052-96 (Reapproved 2002), Standard Test Method for Density and Relative Density of Liquids by Digital...

40 CFR 75.6 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., phone: 610-832-9585, http://www.astm.org/DIGITAL_LIBRARY/index.shtml. (1) ASTM D129-00, Standard Test... Information Reference Unit of the U.S. EPA, 401 M St., SW., Washington, DC and at the Library (MD-35), U.S... D4052-96 (Reapproved 2002), Standard Test Method for Density and Relative Density of Liquids by Digital...

40 CFR 75.6 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., phone: 610-832-9585, http://www.astm.org/DIGITAL_LIBRARY/index.shtml. (1) ASTM D129-00, Standard Test... Information Reference Unit of the U.S. EPA, 401 M St., SW., Washington, DC and at the Library (MD-35), U.S... D4052-96 (Reapproved 2002), Standard Test Method for Density and Relative Density of Liquids by Digital...

78 FR 78956 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

..., Washington, DC 20573, by telephone at (202) 523-5843 or by email at [email protected] . 3PL Logistics, Inc. (NVO...: New NVO License A America Cargo International Logistics LLC (NVO & OFF), 5900 NW. 97th Avenue, Unit 1...: New NVO & OFF License ADN Logistics Group, LLC (OFF), 12030 SW. 129th Court, 103, Miami, FL 33186...

78 FR 37212 - Portland General Electric Company; Notice of Application Accepted for Filing, Soliciting Motions...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-20

... install minimum flow turbine generating units. b. Project No.: 2195-088. c. Date Filed: April 10, 2013. d..., Director of Hydro Licensing and Water Rights, Portland General Electric Company, 121 SW Salmon Street... turbine facilities at four locations: 1) a powerhouse at the base of Timothy Lake Dam housing two...

40 CFR Table 10 to Subpart Hhhhhhh... - HAP Subject to the Resin and Process Wastewater Provisions at New and Existing Sources

Code of Federal Regulations, 2014 CFR

2014-07-01

... SW-846-8015C.a 67561 Methanol Alcohol SW-846-8015C.a 75070 Acetaldehyde Aldehyde SW-846-8315A.a 50000 Formaldehyde Aldehyde SW-846-8315A.a 51285 2,4-dinitrophenol SVOC SW-846-8270D.a 98862 Acetophenone SVOC SW-846...

Effects of exercise in the heat on thermoregulation of Japanese and Malaysian males.

PubMed

Saat, Mohamed; Tochihara, Yutaka; Hashiguchi, Nobuko; Sirisinghe, Roland Gamini; Fujita, Mizuho; Chou, Chin Mei

2005-07-01

The effect of low-intensity exercise in the heat on thermoregulation and certain biochemical changes in temperate and tropical subjects under poorly and well-hydrated states was examined. Two VO2max matched groups of subjects consisting of 8 Japanese (JS) and 8 Malaysians (MS) participated in this study under two conditions: poorly-hydrated (no water was given) and well-hydrated (3 mL x Kg(-1) body weight of water was provided at onset of exercise, and the 15th, 35th and 55th min of exercise). The experimental room in both countries was adjusted to a constant level (Ta: 31.6+/-0.03 degrees C, rh: 72.3+/-0.13%). Subjects spent an initial 10 min rest, 60 min of cycling at 40% VO2max and then 40 min recovery in the experimental room. Rectal temperatures (Tre) skin temperatures (Tsk), heart rate (HR), heat-activated sweat glands density (HASG), local sweat rate (M sw-back) and percent dehydration were recorded during the test. Blood samples were analysed for plasma glucose and lactate levels.The extent of dehydration was significantly higher in the combined groups of JS (1.43+/-0.08%) compared to MS (1.15+/-0.05%). During exercise M sw-back was significantly higher in JS compared to MS in the well-hydrated condition. The HASG was significantly more in JS compared to MS at rest and recovery. Tre was higher in MS during the test. Tsk was significantly higher starting at the 5th min of exercise until the end of the recovery period in MS compared to JS. In conclusion, tropical natives have lower M sw-back associated with higher Tsk and Tre during the rest, exercise and recovery periods. However, temperate natives have higher M sw-back and lower Tsk and Tre during experiments in a hot environment. This phenomenon occurs in both poorly-hydrated and well-hydrated states with low intensity exercise. The differences in M sw-back, Tsk and Tre are probably due to a setting of the core temperature at a higher level and enhancement of dry heat loss, which occurred during passive heat exposure.

Preliminary results constraining the kinematics of subduction and exhumation processes on Skopelos island, Northern Sporades (Aegean Domain)

NASA Astrophysics Data System (ADS)

Porkolab, Kristof; Willingshofer, Ernst; Sokoutis, Dimitrios; Creton, Iverna

2017-04-01

Extension in the Aegean region is a process driven by slab rollback since 45 Ma (e.g. Brun and Sokoutis, 2007; Brun et al. 2016). These and other studies dominantly focused on the northern Aegean/Rhodope or the Cycladic tectonic systems, yielding abundant kinematic, structural, petrologic and geochronological data to constrain their geodynamic evolution. This contrasts with the region of the Northern Sporades, which have not yet been thoroughly studied in the light of subduction-exhumation processes. In particular, a detailed kinematic analysis, the focus of this study, is missing that allows for establishing the relation between the deformation structures on the island, and the large-scale tectonic events in the Aegean domain. The Northern Sporades consist of three major (area ≥ 50km2) islands (Skiathos, Skopelos, and Alonnisos) and a number of smaller islands. As the first phase of exploring the structural evolution of the Northern Sporades, this work reports the results of field work performed on the island of Skopelos, and aims to provide a preliminary model for the deformation history of the island. Skopelos consists from bottom to top of three structural units, which are separated by thrust contacts (Jacobshagen and Wallbrecher, 1984; Matarangas, 1992; Jacobshagen and Matarangas, 2004): the Pelagonian, the Eohellenic, and the Palouki unit. The age of the formations constituting these units ranges from Paleozoic to Paleogene, and all formations have been metamorphosed under lower greenschist or possibly also blueschist facies conditions (Mposkos and Liati, 1991) and experienced polyphase deformation. Based on our field kinematic and structural analysis we suggest the following deformation sequence on Skopelos island: D1 is characterized by tight to isoclinal folding (F1) and the formation of a penetrative foliation (S1), which is the axial plane cleavage to the F1 folds. S1 planes carry a NE-SW trending stretching lineation, along which top-SW shear has been inferred. The second phase of deformation (D2) is defined by top-NE to E shear using the already existing S1 foliation planes in many cases. D2 folding (F2) entails the formation of sheath folds with their axes being sub-parallel to the dominantly NE-SW trending stretching lineation in zones of high strain, upright folds with NE-SW trending axes as well as recumbent folds that affected the already tilted penetrative foliation. The D3 phase is semi-brittle to brittle and is defined by outcrop-to regional-scale fault (and fault-related fold) systems, which have shaped the geometry and elevation of islands and basins of the region until present days. We interpret D1 to reflect prograde metamorphism and top-SW deformation during subduction of the Pelagonian continental block. In contrast, D2 records progressive and distributed top-NE to E extensional deformation and provides the main mechanism for exhuming the previously buried rocks. This phase of deformation was probably triggered by the southward retreat of the Hellenic trench. The emplacement of the Eohellenic and the Palouki units by thrusting (D3) is post-metamorphic and in our view related to the dextral displacement along the fault that borders the North Aegean Trough.

78 FR 56242 - Notice of Realty Action: Competitive Sale of 28 Parcels of Public Land in Clark County, NV

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-12

... acres: T. 20 S., R. 60 E., Sec. 6, NW\\1/4\\SW\\1/4\\SE\\1/4\\, W\\1/2\\NE\\1/4\\SW\\1/4\\SE\\1/4\\, NE\\1/4\\NE\\1/4\\SW\\1/4\\SE\\1/4\\. N-78190, 2.50 acres: T. 22 S., R. 60 E., Sec. 14, NW\\1/4\\SW\\1/4\\NW\\1/4\\SW\\1/4\\. N-91783, 5.00 acres: T. 22 S., R. 60 E., Sec. 14, S\\1/2\\SW\\1/4\\SW\\1/4\\SW\\1/4\\. N-91794, 10.00 acres: T. 22 S...

Generalized Stoner-Wohlfarth model accurately describing the switching processes in pseudo-single ferromagnetic particles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cimpoesu, Dorin, E-mail: cdorin@uaic.ro; Stoleriu, Laurentiu; Stancu, Alexandru

2013-12-14

We propose a generalized Stoner-Wohlfarth (SW) type model to describe various experimentally observed angular dependencies of the switching field in non-single-domain magnetic particles. Because the nonuniform magnetic states are generally characterized by complicated spin configurations with no simple analytical description, we maintain the macrospin hypothesis and we phenomenologically include the effects of nonuniformities only in the anisotropy energy, preserving as much as possible the elegance of SW model, the concept of critical curve and its geometric interpretation. We compare the results obtained with our model with full micromagnetic simulations in order to evaluate the performance and limits of our approach.

States of paleostress north and south of the Periadriatic fault: Comparison of the Drau Range and the Friuli Southalpine wedge

PubMed Central

Bartel, Esther Maria; Neubauer, Franz; Genser, Johann; Heberer, Bianca

2014-01-01

This study focuses on the analysis of structures and kinematics of a N–S profile along the axis of maximum shortening of the European Eastern Alps. The area includes the southern Austroalpine unit in the north and the Southalpine unit, which is a part of the Adriatic indenter. The stratigraphically different units are separated by the Periadriatic fault, the major strike-slip fault within the Alps. In order to assess the kinematics of these units, mainly fault-slip data from north and south of the Periadriatic fault were analyzed. We distinguish a succession of five main kinematic groups in both units: (1) N–S compression; (2) NW–SE compression; (3) NE–SW compression, σ3 changes gradually from subvertical to subhorizontal; (4) N–S compression; and (5) NW–SE compression. Our study reveals that the deformation sequence on either sides of the PAF is similar. The mean orientations of the principal stress axes, however, show small, but consistent differences: The subhorizontal axes north of the Periadriatic fault plunge northward, in the south southward. A counterclockwise (CCW) rotation of the southern part in respect to the north is evident and in line with the well-known counterclockwise rotation of the Adriatic indenter as well as dextral displacement of the N-fanning stress-field along the Periadriatic fault. Opposing plunge directions are interpreted as a primary feature of the internal stress-field within an orogenic wedge further increased during ongoing compression. PMID:27064736

Corrective Action Decision Document for Corrective Action Unit 428: Area 3 Septic Waste Systems 1 and 5, Tonopah Test Range, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

U.S. Department of Energy, Nevada Operations Office

2000-02-08

This Corrective Action Decision Document identifies and rationalizes the US Department of Energy, Nevada Operations Office's selection of a recommended corrective action alternative (CAA) appropriate to facilitate the closure of Corrective Action Unit (CAU) 428, Septic Waste Systems 1 and 5, under the Federal Facility Agreement and Consent Order. Located in Area 3 at the Tonopah Test Range (TTR) in Nevada, CAU 428 is comprised of two Corrective Action Sites (CASs): (1) CAS 03-05-002-SW01, Septic Waste System 1 and (2) CAS 03-05-002- SW05, Septic Waste System 5. A corrective action investigation performed in 1999 detected analyte concentrations that exceeded preliminarymore » action levels; specifically, contaminants of concern (COCs) included benzo(a) pyrene in a septic tank integrity sample associated with Septic Tank 33-1A of Septic Waste System 1, and arsenic in a soil sample associated with Septic Waste System 5. During this investigation, three Corrective Action Objectives (CAOs) were identified to prevent or mitigate exposure to contents of the septic tanks and distribution box, to subsurface soil containing COCs, and the spread of COCs beyond the CAU. Based on these CAOs, a review of existing data, future use, and current operations in Area 3 of the TTR, three CAAs were developed for consideration: Alternative 1 - No Further Action; Alternative 2 - Closure in Place with Administrative Controls; and Alternative 3 - Clean Closure by Excavation and Disposal. These alternatives were evaluated based on four general corrective action standards and five remedy selection decision factors. Based on the results of the evaluation, the preferred CAA was Alternative 3. This alternative meets all applicable state and federal regulations for closure of the site and will eliminate potential future exposure pathways to the contaminated soils at the Area 3 Septic Waste Systems 1 and 5.« less

Use of On-Site GC/MS Analysis to Distinguish Between Vapor Intrusion and Indoor Sources of VOCs

DTIC Science & Technology

2013-11-01

Toxaphene, Volatile Organics, Acid Extractables, Benzidines, Phthalates, Nitrosamines, Nitroaromatics & Cyclic Ketones , PAHs, Haloethers, Chlorinated...SW 8270), Nitrosamines (SW 8270), Nitroaromatics & Cyclic Ketones (SW 8270), PAHs (SW 8270), Haloethers (SW 8270), Chlorinated Hydrocarbons (SW 8270...alpha-BHC, beta-BHC, gamma-BHC, delta-BHC, Dieldrin, DDD, DDE, DDT,Endosulfan I, Endosulfan II, Endosulfan sulfate, Endrin, Endrin Aldehyde

Unequal cluster sizes in stepped-wedge cluster randomised trials: a systematic review.

PubMed

Kristunas, Caroline; Morris, Tom; Gray, Laura

2017-11-15

To investigate the extent to which cluster sizes vary in stepped-wedge cluster randomised trials (SW-CRT) and whether any variability is accounted for during the sample size calculation and analysis of these trials. Any, not limited to healthcare settings. Any taking part in an SW-CRT published up to March 2016. The primary outcome is the variability in cluster sizes, measured by the coefficient of variation (CV) in cluster size. Secondary outcomes include the difference between the cluster sizes assumed during the sample size calculation and those observed during the trial, any reported variability in cluster sizes and whether the methods of sample size calculation and methods of analysis accounted for any variability in cluster sizes. Of the 101 included SW-CRTs, 48% mentioned that the included clusters were known to vary in size, yet only 13% of these accounted for this during the calculation of the sample size. However, 69% of the trials did use a method of analysis appropriate for when clusters vary in size. Full trial reports were available for 53 trials. The CV was calculated for 23 of these: the median CV was 0.41 (IQR: 0.22-0.52). Actual cluster sizes could be compared with those assumed during the sample size calculation for 14 (26%) of the trial reports; the cluster sizes were between 29% and 480% of that which had been assumed. Cluster sizes often vary in SW-CRTs. Reporting of SW-CRTs also remains suboptimal. The effect of unequal cluster sizes on the statistical power of SW-CRTs needs further exploration and methods appropriate to studies with unequal cluster sizes need to be employed. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Insights Into Intermediate Ocean Barium Cycling From Deep-Sea Bamboo Coral Records on the California Margin

NASA Astrophysics Data System (ADS)

LaVigne, M.; Serrato Marks, G.; Freiberger, M. M.; Miller, H. R.; Hill, T. M.; McNichol, A. P.; Lardie Gaylord, M.

2016-02-01

Dissolved barium (BaSW) has been linked to several biogeochemical processes such as the cycling and export of nutrients, organic carbon (Corg), and barite in surface and intermediate oceans. The dynamic nature of barium cycling in the water column has been demonstrated on short timescales (days-weeks) while sedimentary records have documented geologic-scale changes in barite preservation driven by export production. Our understanding of how inter-annual-decadal scale climate variability impacts these biogeochemical processes currently lacks robust instrumental and paleoceanographic records. Recent work has calibrated and demonstrated the reproducibility of a new BaSW proxy in California Current System (CCS) bamboo corals (Ba/Ca) using a coral depth transect spanning the CCS oxygen minimum zone (792-2055m water depth). New `reconnaissance' radiocarbon data identifying the bomb 14C spike in coral proteinaceous nodes and sclerochronological analyses of calcitic internodes are used to assign chronologies to the CCS coral records. Century-long coral records from 900-1500m record 4-7 year long increases in Ba/Ca ( 10-70 nmol/kg BaSW) at depths where rapid barite cycling occurs on day-weekly timescales. The BaSW peaks punctuate the coral records at different time periods and depths and do not coincide with inter-annual/decadal climate transitions (e.g. ENSO/PDO). Stable surface productivity and coral δ15N records indicate that Corg export from CCS surface waters has been relatively constant over the past century. Thus, the inter-annual scale BaSW peaks recorded by the 900-1500m corals more likely reflect periods of decreased barite formation (and/or increased dissolution) via reduced bacterial Corg respiration or barite saturation state. Paleoceanographic BaSW records and continued research on barium cycling in the modern ocean have the potential to elucidate the mechanisms linking intermediate water carbon and barium cycling, climate, and ocean oxygenation in the past.

75 FR 27806 - Notice of Submission of Proposed Information Collection to OMB Emergency Comment Request...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-18

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-38] Notice of Submission of... Communities, Room 10180. Department of Housing and Urban Development, 451 Seventh Street, SW., Washington, DC... percent of the federal poverty level, or, if a state chooses, 60 percent of the State's median income. The...

Risk of HIV infection among indoor and street sex workers and their use of health services in Belgrade, Serbia.

PubMed

Ilić, Dragan; Sipetić, Sandra; Bjegović, Vesna

2010-01-01

HIV in Serbia is most often transmitted through sexual contact, and therefore numerous prevention activities are geared towards sex workers (SW). To analyse the differences in knowledge, attitudes and risky behaviour between indoor and street SW in Belgrade; to examine the accessibility of health services to this vulnerable group. In this behavioural cross-sectional study, 113 street and 78 indoor SW were included. The sampling method used was snowball samples. Data were gathered through structured questionnaires. Around 15% of respondents used drugs intravenously. Around 60% of SW used a condom during the last sexual intercourse with their private partner, and around 90% with a commercial partner. Indoor SW had lower levels of education more often than outdoor SW, and they used marijuana, sedatives and painkillers on a daily basis. A significantly higher number of indoor SW were informed about HIV, HBV and HCV testing, and that the risk for HIV infection is not lower ifa condom is used exclusively for vaginal sex. Indoor SW reported using health services and testing and counselling for HIV, HBV and HCV more frequently than outdoor SW. Outdoor SW had significantly more sex partners in the previous month than indoor SW. Indoor SW recognized more frequently that providing sex services posed a higher risk for HIV infection. The results of this research study show that even though outdoor SW had higher levels of education than indoor SW, their level of knowledge about HIV transmission was lower and they reported more risky behaviour than indoor SW. Data show that both groups reported not taking care of their health.

Bitburg Air Base, West Germany. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

DTIC Science & Technology

1982-06-29

equals none for the month (tenths) = TRENE DAILY SNOW DEPTH1 Ŕ’ equals none for the month (whole inches) 3. The third set of two tables provides the total...30SW 38 W 33Sw 48WSW 41ISSW 34 SW 4 65 wSW 45 NW 355SW 4OW 32 NW 40$W 50 SW 36- 34 SW 421WSW 32W 914W 56 SI W- 46 386 58 i E *19k 38 SE 54SW 26SW *20WSW...2227/ 2 3 24/ 3 24/ 5 79 2 1 35 1 2 2 3 3/ 322 / 4 %/1 25 3922/ 28 4$ 252 / S222 451 46 251 4e 83 .’ 2 / 1 4 9 / 44 2 / 3 6 / . 9/ 2 6 7 3S

The Weichselian (Würmian) Pleniglacial chronology of the Nussloch loess section/Germany revisited. Implications for the matching of pedosedimentary units with Greenland stadial and interstadial periods.

NASA Astrophysics Data System (ADS)

Kadereit, A.; Kind, C.-J.; Wagner, G. A.

2012-04-01

The loess section of Nussloch in SW-Germany is a key profile for the reconstruction of the terrestrial palaeoenvironment of central Europe for the time of the Weichselian (Würmian) Pleniglacial (e.g. Antoine et al., 2009). In this period, the earliest modern humans invaded SW-Germany as documented in unique cultural remains from karst caves of the Swabian Jura (e.g. Conard et al., 2009). The Nussloch profile includes a Middle Pleniglacial Cambisol remain (Lohne Soil), which serves as an important loess marker horizon throughout Europe. Greenland interstadial (GIS) 8 was hitherto regarded as the likely period of soil formation for the Lohne Soil and a suite of partly soliflucted Cryosols in the hanging wall is interpreted to represent warm climate excursions of the Upper Pleniglacial period, starting with GIS8 or GIS7 (e.g. Antoine et al., 2001, 2009; Rousseau et al., 2011). However, revaluation of available chronometric data from Nussloch suggests (GIS7 to) GIS5 as the likely period of soil formation for the Lohne Soil. GIS8 is documented by deposits from thermokarst dynamics, stratigraphically several units below the marker soil. Consequences of a revised chronology for correlations of Pleniglacial Cryosols below and above the Lohne Soil with Greenland interstadials are discussed. The implications are important for European loess research as the Nussloch section serves as a reference base throughout Europe. The revised chronology suggests also that the Lohne Soil postdates the immigration of the earliest modern humans in SW-Germany and central Europe. This finding is in contrast to the earlier age-model for the Nussloch site.

Electronic and magnetic properties of zigzag silicene nanoribbons with Stone–Wales defects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dong, Haixia; Institute of Solid State Physics, Shanxi Datong University, Datong 037009; Fang, Dangqi

2015-02-14

The structural, electronic, and magnetic properties of zigzag silicene nanoribbons (ZSiNRs) with Stone–Wales (SW) defects were investigated using first-principles calculations. We found that two types of SW defects (named SW-Ι and SW-ΙΙ) exist in ZSiNRs. The SW defect was found to be the most stable at the edge of the ZSiNR, independently of the defect orientation, even more stable than it is in an infinite silicene sheet. In addition, the ZSiNRs can transition from semiconductor to metal or half-metal by modifying the SW defect location and concentration. For the same defect concentration, the band structures influenced by the SW-Ι defectmore » are more distinct than those influenced by the SW-ΙΙ when the SW defect is at the edge. The present study suggests the possibility of tuning the electronic properties of ZSiNRs using the SW defects and might motivate their potential application in nanoelectronics and spintronics.« less

Selection and use of microsatellite markers for individual identification and meat traceability of six swine breeds in the Chinese market.

PubMed

Zhao, Jie; Li, Tingting; Zhu, Chao; Jiang, Xiaoling; Zhao, Yan; Xu, Zhenzhen; Yang, Shuming; Chen, Ailiang

2018-06-01

Meat traceability based on molecular markers is exerting a great influence on food safety and will enhance its key role in the future. This study aimed to investigate and verify the polymorphism of 23 microsatellite markers and select the most suitable markers for individual identification and meat traceability of six swine breeds in the Chinese market. The mean polymorphism information content value of these 23 loci was 0.7851, and each locus exhibited high polymorphism in the pooled population. There were 10 loci showing good polymorphism in each breed, namely, Sw632, S0155, Sw2406, Sw830, Sw2525, Sw72, Sw2448, Sw911, Sw122 and CGA. When six highly polymorphic loci were combined, the match probability value for two random individual genotypes among the pig breeds (Beijing Black, Sanyuan and Taihu) was lower than 1.151 E-06. An increasing number of loci indicated a gradually decreasing match probability value and therefore enhanced traceability accuracy. The validation results of tracing 18 blood and corresponding meat samples based on five highly polymorphic loci (Sw2525, S0005, Sw0107, Sw911 and Sw857) were successful, with 100% conformation probability, which provided a foundation for establishing a traceability system for pork in the Chinese market.

18. Historic American Buildings Survey W. N. Manning, Photographer, March ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Historic American Buildings Survey W. N. Manning, Photographer, March 28, 1935 OLD SLAVE AND SMOKE HOUSES AT REAR OF BLDG. S.W. COR. - Haygood House, State Highway 97 (County Road 29), Lowndesboro, Lowndes County, AL

NAVSEA 05D Ship Design and Certification Network Knowledge Management Project

DTIC Science & Technology

2007-09-12

Junod , Vinek Kaistha N SW C C D -C IS D -2 00 7/ 00 1 REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this...NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 6. AUTHOR(S) John Junod , LCdr Mark Read, Vinek Kaistha 5f. WORK UNIT NUMBER 06-1-2002

The Eocene-Miocene tectonic evolution of the Rif chain (Morocco): new data from the Jebha area

NASA Astrophysics Data System (ADS)

D'Assisi Tramparulo, Francesco; Ciarcia, Sabatino; El Ouaragli, Bilal; Vitale, Stefano; Najib Zaghloul, Mohamed

2016-04-01

Keywords: structural analysis, tectonics, shear bands, Miocene, Jebha Fault The Jebha area, located in the Central Rif, is a key sector to understand the orogenic evolution of the Rif chain. Here, the left lateral Jebha-Chrafate transfer fault, allowed, in the Miocene time, the westward migration of the internal thrust front. The structural analysis of the area revealed a complex tectonic history. The Eocene orogenic pulse produced the tectonic stacking of the Ghomaride thrust sheets. During the late Aquitanian and Langhian, under a dominant ENE-WSW shortening, imbrication of several Internal Dorsale Calcaire slices occurred. The following orogenic stage, characterized by a main SE tectonic transport, allowed the External Dorsale Calcaire to overthrust the Maghrebian Flysch Basin Units by means of a dominant thin-skinned tectonics. Synchronously with the buttressing following the collision of the allochthonous wedge against the External Rif domain, an out-of-sequence thrusting stage involved the Ghomaride and Dorsale Calcaire Units and a general back-thrusting deformed the entire tectonic pile. A renewal of the NE-SW shortening produced strike-slip faults and SW-verging folds and finally a radial extension affected the whole chain.

ExoMars Raman laser spectrometer overview

NASA Astrophysics Data System (ADS)

Rull, F.; Sansano, A.; Díaz, E.; Canora, C. P.; Moral, A. G.; Tato, C.; Colombo, M.; Belenguer, T.; Fernández, M.; Manfredi, J. A. R.; Canchal, R.; Dávila, B.; Jiménez, A.; Gallego, P.; Ibarmia, S.; Prieto, J. A. R.; Santiago, A.; Pla, J.; Ramos, G.; González, C.

2010-09-01

The Raman Laser Spectrometer (RLS) is one of the Pasteur Payload instruments, within the ESA's Aurora Exploration Programme, ExoMars mission. The RLS Instrument will perform Raman spectroscopy on crushed powered samples deposited on a small container after crushing the cores obtained by the Rover's drill system. This is the first time that a Raman spectrometer will be launched in an out planetary mission. The Instrument will be accommodated and operate inside the Rover's ALD (Analytical Laboratory Drawer), complying with COSPAR (Committee on Space Research) Planetary Protection requirements. The RLS Instrument is composed by the following units: SPU (Spectrometer Unit); iOH: (Internal Optical Head); ICEU (Instrument Control and Excitation Unit). Other instrument units are EH (Electrical Harness), OH (Optical Harness) and RLS SW On-Board.

40 CFR Table 10 to Subpart Hhhhhhh... - HAP Subject to the Resin and Process Wastewater Provisions at New and Existing Sources

Code of Federal Regulations, 2013 CFR

2013-07-01

... Alcohol SW-846-8015C.a 67561 Methanol Alcohol SW-846-8015C.a 75070 Acetaldehyde Aldehyde SW-846-8315A.a 50000 Formaldehyde Aldehyde SW-846-8315A.a 51285 2,4-dinitrophenol SVOC SW-846-8270D.a 98862...

Stress direction history of the western United States and Mexico since 85 Ma

NASA Astrophysics Data System (ADS)

Bird, Peter

2002-06-01

A data set of 369 paleostress direction indicators (sets of dikes, veins, or fault slip vectors) is collected from previous compilations and the geologic literature. Like contemporary data, these stress directions show great variability, even over short distances. Therefore statistical methods are helpful in deciding which apparent variations in space or in time are significant. First, the interpolation technique of Bird and Li [1996] is used to interpolate stress directions to a grid of evenly spaced points in each of seventeen 5-m.y. time steps since 85 Ma. Then, a t test is used to search for stress direction changes between pairs of time windows whose sense can be determined with some minimum confidence. Available data cannot resolve local stress provinces, and only the broadest changes affecting country-sized regions are reasonably certain. During 85-50 Ma, the most compressive horizontal stress azimuth $\\hat \\sigma $1H was fairly constant at ~68° (United States) to 75° (Mexico). During 50-35 Ma, both counterclockwise stress changes (in the Pacific Northwest) and clockwise stress changes (from Nevada to New Mexico) are seen, but only locally and with about 50% confidence. A major stress azimuth change by ~90° occurred at 33 +/- 2 Ma in Mexico and at 30 +/- 2 Ma in the western United States. This was probably an interchange between $\\hat \\sigma $1 and $\\hat \\sigma $3 caused by a decrease in horizontal compression and/or an increase in vertical compression. The most likely cause was the rollback of horizontally subducting Farallon slab from under the southwestern United States and northwest Mexico, which was rapid during 35-25 Ma. After this transition, a clockwise rotation of principal stress axes by 36°-48° occurred more gradually since 22 Ma, affecting the region between latitudes 28°N and 41°N. This occurred as the lengthening Pacific/North America transform boundary gradually added dextral shear on northwest striking planes to the previous stress field of SW-NE extension.

Mercury toxicokinetics-dependency on strain and gender

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ekstrand, Jimmy; Nielsen, Jesper B.; Havarinasab, Said

Mercury (Hg) exposure from dental amalgam fillings and thimerosal in vaccines is not a major health hazard, but adverse health effects cannot be ruled out in a small and more susceptible part of the exposed population. Individual differences in toxicokinetics may explain susceptibility to mercury. Inbred, H-2-congenic A.SW and B10.S mice and their F1- and F2-hybrids were given HgCl{sub 2} with 2.0 mg Hg/L drinking water and traces of {sup 203}Hg. Whole-body retention (WBR) was monitored until steady state after 5 weeks, when the organ Hg content was assessed. Despite similar Hg intake, A.SW males attained a 20-30% significantly highermore » WBR and 2- to 5-fold higher total renal Hg retention/concentration than A.SW females and B10.S mice. A selective renal Hg accumulation but of lower magnitude was seen also in B10.S males compared with females. Differences in WBR and organ Hg accumulation are therefore regulated by non-H-2 genes and gender. Lymph nodes lacked the strain- and gender-dependent Hg accumulation profile of kidney, liver and spleen. After 15 days without Hg A.SW mice showed a 4-fold higher WBR and liver Hg concentration, but 11-fold higher renal Hg concentration, showing the key role for the kidneys in explaining the slower Hg elimination in A.SW mice. The trait causing higher mercury accumulation was not dominantly inherited in the F1 hybrids. F2 mice showed a large inter-individual variation in Hg accumulation, showing that multiple genetic factors influence the Hg toxicokinetics in the mouse. The genetically heterogeneous human population may therefore show a large variation in mercury toxicokinetics.« less

Small-worldness characteristics and its gender relation in specific hemispheric networks.

PubMed

Miraglia, F; Vecchio, F; Bramanti, P; Rossini, P M

2015-12-03

Aim of this study was to verify whether the topological organization of human brain functional networks is different for males and females in resting state EEGs. Undirected and weighted brain networks were computed by eLORETA lagged linear connectivity in 130 subjects (59 males and 71 females) within each hemisphere and in four resting state networks (Attentional Network (AN), Frontal Network (FN), Sensorimotor Network (SN), Default Mode Network (DMN)). We found that small-world (SW) architecture in the left hemisphere Frontal network presented differences in both delta and alpha band, in particular lower values in delta and higher in alpha 2 in males respect to females while in the right hemisphere differences were found in lower values of SW in males respect to females in gamma Attentional, delta Sensorimotor and delta and gamma DMNs. Gender small-worldness differences in some of resting state networks indicated that there are specific brain differences in the EEG rhythms when the brain is in the resting-state condition. These specific regions could be considered related to the functions of behavior and cognition and should be taken into account both for research on healthy and brain diseased subjects. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

Electronic State of Sodium trans-[Tetrachloridobis(1H-indazole)ruthenate(III)] (NKP-1339) in Tumor, Liver and Kidney Tissue of a SW480-bearing Mouse

PubMed Central

Blazevic, Amir; Hummer, Alfred A.; Heffeter, Petra; Berger, Walter; Filipits, Martin; Cibin, Giannantonio; Keppler, Bernhard K.; Rompel, Annette

2017-01-01

Ruthenium complexes are promising candidates for anticancer agents, especially NKP-1339 (sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)]), which is on the edge to clinical applications. The anticancer mechanism seems to be tightly linked to the redox chemistry but despite progress in human clinical trials the in vivo Ru oxidation state and the coordination of Ru remains unclear. The Ru-based anticancer drug NKP-1339 was studied applying XANES (Cl K- and Ru L2,3-edges) in tumor, kidney and liver tissue of a SW480 bearing mouse. Based on coordination charge and 3D XANES plots containing a series of model compounds as well as pre-edge analysis of the ligand Cl K-edge it is suggested that NKP-1339 remains in its +III oxidation state after 24 hours and at least one of the four chlorido ligands remain covalently bound to the Ru ion showing a biotransformation from RuIIIN2Cl4 to RuIIIClx(N/O)6−x (X = 1 or 2). PMID:28112202

Electronic State of Sodium trans-[Tetrachloridobis(1H-indazole)ruthenate(III)] (NKP-1339) in Tumor, Liver and Kidney Tissue of a SW480-bearing Mouse

NASA Astrophysics Data System (ADS)

Blazevic, Amir; Hummer, Alfred A.; Heffeter, Petra; Berger, Walter; Filipits, Martin; Cibin, Giannantonio; Keppler, Bernhard K.; Rompel, Annette

2017-01-01

Ruthenium complexes are promising candidates for anticancer agents, especially NKP-1339 (sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)]), which is on the edge to clinical applications. The anticancer mechanism seems to be tightly linked to the redox chemistry but despite progress in human clinical trials the in vivo Ru oxidation state and the coordination of Ru remains unclear. The Ru-based anticancer drug NKP-1339 was studied applying XANES (Cl K- and Ru L2,3-edges) in tumor, kidney and liver tissue of a SW480 bearing mouse. Based on coordination charge and 3D XANES plots containing a series of model compounds as well as pre-edge analysis of the ligand Cl K-edge it is suggested that NKP-1339 remains in its +III oxidation state after 24 hours and at least one of the four chlorido ligands remain covalently bound to the Ru ion showing a biotransformation from RuIIIN2Cl4 to RuIIIClx(N/O)6-x (X = 1 or 2).

Expression of the proto-oncogene Pokemon in colorectal cancer--inhibitory effects of an siRNA.

PubMed

Zhao, Gan-Ting; Yang, Li-Juan; Li, Xi-Xia; Cui, Hui-Lin; Guo, Rui

2013-01-01

This study aimed to investigate expression of the proto-oncogene POK erythroid myeloid ontogenic factor (Pokemon) in colorectal cancer (CRC), and assess inhibitory effects of a small interference RNA (siRNA) expression vector in SW480 and SW620 cells. Semi-quantitative reverse transcription-polymerase chain reaction (PCR) and immunohistochemistry were performed to determine mRNA and protein expression levels of Pokemon in CRC tissues. Indirect immunofluorescence staining was applied to investigate the location of Pokemon in SW480 and SW620 cells. The siRNA expression vectors that were constructed to express a short hairpin RNA against Pokemon were transfected to the SW480 and SW620 cells with a liposome. Expression levels of Pokemon mRNA and protein were examined by real-time quantitative-fluorescent PCR and western blot analysis. The effects of Pokemon silencing on proliferation of SW480 and SW620 cells were evaluated with reference to growth curves with MTT assays. The mRNA expression level of Pokemon in tumor tissues (0.845 ± 0.344) was significantly higher than that in adjacent tumor specimens (0.321 ± 0.197). The positive expression ratio of Pokemon protein in CRC (87.0%) was significantly higher than that in the adjacent tissues (19.6%). Strong fluorescence staining of Pokemon protein was observed in the cytoplasm of the SW480 and SW620 cells. The inhibition ratios of Pokemon mRNA and protein in the SW480 cells were 83.1% and 73.5% at 48 and 72 h, respectively, compared with those of the negative control cells with the siRNA. In the SW620 cells, the inhibition ratios of Pokemon mRNA and protein were 76.3% and 68.7% at 48 and 72 h, respectively. MTT showed that Pokemon gene silencing inhibited the proliferation of SW480 and SW620 cells. Overexpression of Pokemon in CRC may have a function in carcinogenesis and progression. siRNA expression vectors could effectively inhibit mRNA and protein expression of Pokemon in SW480 and SW620 cells, thereby reducing malignant cell proliferation.

Structural Evolution of a Crustal Scale Tectonic Boundary in the 1 Ga Sveconorwegian Orogen, SW Sweden.

NASA Astrophysics Data System (ADS)

Pinan-Llamas, A.; Möller, C.; Andersson, J.

2016-12-01

We present new structural data to document Sveconorwegian deformational structures preserved in rocks of the Idefjorden Terrane (IT), the Eastern Segment (ES) and a formerly deep-seated tectonic boundary between them, the Mylonite Zone (MZ), in SW Sweden. We aim to integrate structural, petrologic and geochronological data to reconstruct a model for the Sveconorwegian deformation. The SE-vergent MZ is a crustal scale thrust that juxtaposed the allochtonous IT in the hanging wall against the eclogite-bearing ES in the footwall during the Sveconorwegian orogeny. In the research area, rocks of the IT are characterized by a roughly N-S striking tectonic banding that dips shallowly to the W and contains west or WNW-plunging stretching lineations. This gneissic banding is folded by asymmetric and overturned S- or SW-verging similar folds, which in highly strained areas become isoclinal and recumbent. In sections parallel to the lineation, most kinematic indicators are consistent with a top-down-to-the-west sense of shear, i.e. accommodating E-W extension. At the terrane boundary (MZ), ultramylonites and sheath folds are locally present. Immediately east of the MZ, rocks of the ES show a NW-SE to NE-SW striking tectonic banding (Sc) containing shallowly W- and SW-plunging stretching lineations. Sc locally preserves kinematic indicators and intrafolial folds (F1) that we relate to a first Sveconorwegian deformation phase D1. D1 fabrics were folded by asymmetric NE-SW to E-W trending F2 similar folds that are SE- to S-verging. In highly strained areas, these folds are isoclinal and recumbent. The main stretching lineation is sub-parallel to F2 fold axes. In sections subparallel to the lineation, kinematic indicators show a top-down-to-the-west or southwest sense of shear, including extensional shear bands that are overprinting F2 folds. Upright open F3 folds affect earlier fabrics. While D1 fabrics likely resulted from foreland-directed (east-vergent) thrusting that juxtaposed an eclogite-bearing terrane with eclogite-free units in the ES, D2 fabrics (shear-related folds and subsequent shear bands) may be related to E-W or NW-SE extensional or transtensional deformation after the main contractional phases of the orogeny. F3 folds might have resulted from accommodation during protracted E-W extension.

To Plume or Not To Plume: SC Mesozoic Diabase Dike Orientations, Stress Fields During the Break-up of Pangea, and the Feasibility of a Causal Plume.

NASA Astrophysics Data System (ADS)

Beutel, E. K.; Alexander, M.; Kotecha, A.; Edwards, D.

2002-12-01

New compilations of Mesozoic diabase dikes in South Carolina suggest that previously unrecognized N-S and NE-SW dike orientations exist throughout the western Charlotte belt, into the Carolina belt and possible into the Laurens Thrust Stack. Previous studies indicated that the majority of dikes in South Carolina were solely NW trending. While we found that the majority of dikes did trend NW-SE, the number and size of the NE-SW and N-S trending dikes indicate that these are not mere fingers off the main NW trending dikes and are likely true swarms. Previous studies of Mesozoic diabase dikes further north along the Atlantic coast have found evidence that suggests that NW-SE trending dikes are the oldest set, the N-S trending set followed, and the NE-SW trending dikes were injected last. Based on this relationship, and the stress field that most likely existed in the crust during the injection of each dike set, we have constructed a series of evolutionary models for the break-up of Pangea. Our models are based on the assumption that the multiple overlapping swarms negate the possibility of a plume being solely responsible for the break-up or for the dikes. These models suggest a complicated history of relative motion between Africa, North America, and South America. Finite element models were run to test the feasibility of these models. Preliminary model results suggest that the extensional stresses necessary for the major dike patterns seen in northwestern Africa, northern South America, and the southeastern United States may have occurred when the relative motion of Africa was northeast of North America. Initial model runs suggest that multiple dike orientations are best accounted for by a strongly nonlinear rift trend, a temporary aulacogen in Georgia, and/or rift propagation. The affect of events in the Gulf of Mexico is strongly dependent on the location and trend of the rifts and micro-continents modeled.

Large-scale solar wind streams: Average temporal evolution of parameters

NASA Astrophysics Data System (ADS)

Yermolaev, Yuri; Lodkina, Irina; Yermolaev, Michael; Nikolaeva, Nadezhda

2016-07-01

In the report we describe the average temporal profiles of plasma and field parameters in the disturbed large-scale types of solar wind (SW): corotating interaction regions (CIR), interplanetary coronal mass ejections (ICME) (both magnetic cloud (MC) and Ejecta), and Sheath as well as the interplanetary shock (IS) on the basis of OMNI database and our Catalog of large-scale solar wind phenomena during 1976-2000 (see website ftp://ftp.iki.rssi.ru/pub/omni/ and paper [Yermolaev et al., 2009]). To consider influence of both the surrounding undisturbed solar wind, and the interaction of the disturbed types of the solar wind on the parameters, we separately analyze the following sequences of the phenomena: (1) SW/CIR/SW, (2) SW/IS/CIR/SW, (3) SW/Ejecta/SW, (4) SW/Sheath/Ejecta/SW, (5) SW/IS/Sheath/Ejecta/SW, (6) SW/MC/SW, (7) SW/Sheath/MC/SW, and (8) SW/IS/Sheath/MC/SW. To take into account the different durations of SW types, we use the double superposed epoch analysis (DSEA) method: rescaling the duration of the interval for all types in such a manner that, respectively, beginning and end for all intervals of selected type coincide [Yermolaev et al., 2010; 2015]. Obtained data allow us to suggest that (1) the behavior of parameters in Sheath and in CIR is very similar not only qualitatively but also quantitatively, and (2) the speed angle phi in ICME changes from 2 to -2deg. while in CIR and Sheath it changes from -2 to 2 deg., i.e., the streams in CIR/Sheath and ICME deviate in the opposite side. The work was supported by the Russian Foundation for Basic Research, project 16-02-00125 and by Program of Presidium of the Russian Academy of Sciences. References: Yermolaev, Yu. I., N. S. Nikolaeva, I. G. Lodkina, and M. Yu. Yermolaev (2009), Catalog of Large-Scale Solar Wind Phenomena during 1976-2000, Cosmic Research, , Vol. 47, No. 2, pp. 81-94. Yermolaev, Y. I., N. S. Nikolaeva, I. G. Lodkina, and M. Y. Yermolaev (2010), Specific interplanetary conditions for CIR-induced, Sheath-induced, and ICME-induced geomagnetic storms obtained by double superposed epoch analysis, Ann. Geophys., 28, pp. 2177-2186. Yermolaev, Yu. I., I. G. Lodkina, N. S. Nikolaeva, and M. Yu. Yermolaev (2015), Dynamics of large-scale solar wind streams obtained by the double superposed epoch analysis, J. Geophys. Res. Space Physics, 120, doi:10.1002/2015JA021274

Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hu, Yamei; Wang, Lingxian; Wang, Lu

2015-02-15

Liposarcoma is the most common soft tissue sarcoma with a high risk of relapse. Few therapeutic options are available for the aggressive local or metastatic disease. Here, we report that the clinically used proteasome inhibitor bortezomib exhibits significantly stronger cytotoxicity toward highly malignant human liposarcoma SW872-S cells compared with its parental SW872 cells, which is accompanied by enhanced activation of apoptotic signaling both in vitro and in vivo. Treatment of cells with Jun-N-terminal kinase (JNK) inhibitor SP60015 or the translation inhibitor cycloheximide ameliorated this enhanced apoptosis. Bortezomib inhibited MDR1 expression and function more effectively in SW872-S cells than in SW872more » cells, indicating that the increased cytotoxicity relies on the degree of proteasome inhibition. Furthermore, the pharmacological or genetic inhibition of sarco/endoplasmic reticulum calcium-ATPase (SERCA) 2, which is highly expressed in SW872-S cells, resulted in partial reversal of cell growth inhibition and increase of MDR1 expression in bortezomib-treated SW872-S cells. These results show that bortezomib exhibits preferential cytotoxicity toward SW872-S cells possibly via highly expressed SERCA2-associated MDR1 suppression and suggest that bortezomib may serve as a potent agent for treating advanced liposarcoma. - Highlights: • We compare the cytotoxicity of different drugs between SW872-S and SW872 cells. • Highly malignant liposarcoma cells SW872-S show hypersensitivity to bortezomib. • Apoptotic signaling is robustly enhanced in bortezomib-treated SW872-S cells. • Bortezomib has strong suppression on MDR1 expression and function in SW872-S cells. • Inhibition of SERCA2 protects SW872-S cells from bortezomib.« less

SBA Innovation Clusters

DTIC Science & Technology

2012-03-02

Programs and services to help you start, grow and succeed www.sba.gov U.S. Small Business Administration Your Small Business Resource 1Approved for...Public Release SBA Innovation Clusters RADM Steven G. Smith USN (Ret) Advanced Defense Technology Cluster Coordinator U.S. Small Business ...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Small Business Administration ,Advanced Defense Technology Cluster,409 3rd St, SW

HESS Opinions "Integration of groundwater and surface water research: an interdisciplinary problem?"

NASA Astrophysics Data System (ADS)

Barthel, R.

2014-07-01

Today there is a great consensus that water resource research needs to become more holistic, integrating perspectives of a large variety of disciplines. Groundwater and surface water (hereafter: GW and SW) are typically identified as different compartments of the hydrological cycle and were traditionally often studied and managed separately. However, despite this separation, these respective fields of study are usually not considered to be different disciplines. They are often seen as different specializations of hydrology with a different focus yet similar theory, concepts, and methodology. The present article discusses how this notion may form a substantial obstacle in the further integration of GW and SW research and management. The article focuses on the regional scale (areas of approximately 103 to 106 km2), which is identified as the scale where integration is most greatly needed, but ironically where the least amount of fully integrated research seems to be undertaken. The state of research on integrating GW and SW research is briefly reviewed and the most essential differences between GW hydrology (or hydrogeology, geohydrology) and SW hydrology are presented. Groundwater recharge and baseflow are used as examples to illustrate different perspectives on similar phenomena that can cause severe misunderstandings and errors in the conceptualization of integration schemes. The fact that integration of GW and SW research on the regional scale necessarily must move beyond the hydrological aspects, by collaborating with the social sciences and increasing the interaction between science and society in general, is also discussed. The typical elements of an ideal interdisciplinary workflow are presented and their relevance with respect to the integration of GW and SW is discussed. The overall conclusions are that GW hydrology and SW hydrogeology study rather different objects of interest, using different types of observation, working on different problem settings. They have thus developed a different theory, methodology and terminology. However, there seems to be a widespread lack of awareness of these differences, which hinders the detection of the existing interdisciplinary aspects of GW and SW integration and consequently the development of a truly unifying interdisciplinary theory and methodology. Thus, despite having the ultimate goal of creating a more holistic approach, we may have to start integration by analyzing potential disciplinary differences. Improved understanding among hydrologists of what interdisciplinary means and how it works is needed. Hydrologists, despite frequently being involved in multidisciplinary projects, are not sufficiently involved in developing interdisciplinary strategies and do usually not regard the process of integration as such as a research topic of its own. There seems to be a general reluctance to apply a (truly) interdisciplinary methodology because this is tedious and few immediate incentives are experienced. The objective of the present opinion paper is to stimulate a discussion rather than to provide recipes on how to integrate GW and SW research or to explain how specific problems of GW-SW interaction should be solved on a technical level. For that purpose it presents complicated topics in a rather simplified, bold way, ignoring to some degree subtleties and potentially controversial issues.

Identifying Faults Associated with the 2001 Avoca Induced(?) Seismicity Sequence of Western New York State Using Potential Field Wavelets.

NASA Astrophysics Data System (ADS)

Horowitz, F. G.; Ebinger, C.; Jordan, T. E.

2017-12-01

Results from recent DOE and USGS sponsored projects in the (intraplate) northeastern portions of the US and southeastern portions of Canada have identified locations of steeply dipping structures - many previously unknown - from a Poisson wavelet multiscale edge ('worm') analysis of gravity and magnetic fields. The Avoca sequence of induced(?) seismicity in western New York state occurred during January and February of 2001. The Avoca earthquake sequence is associated with industrial hydraulic fracturing activity "related to a proposed natural gas storage facility near Avoca to be constructed by solution mining" (Kim, 2001). The main Avoca event was a felt Mb = 3.2 earthquake on Feb. 3, 2001 recorded by the Lamont Cooperative Seismic Network. Earlier, smaller events were located by the Canadian Geological Survey's seismic network north of the Canadian border - implying that the event locations might be biased because they occurred off the southern edge of the array. Some of these events were also felt locally, according to local newspaper reports. By plotting the location of the seismic events and that of the injection well - reported via it's API number - we find a strong correlation with structures detected via our potential field worms. The injection occurred near a NE-SW striking structure that was not activated. All but one of the earthquakes occurred about 5 km north of the injection well on or nearby to an E-W striking structure that appears to intersect the NE-SW structure. The final, small (MN=2.2) earthquake was located on a different complex structure about 10 km north of the other events. We suggest that potential field methods such as ours might be appropriate to locating structures of concern for induced seismic activity in association with industrial activity. Reference: Kim, W.-Y. (2001). The Lamont cooperative seismic network and the national seismic system: Earthquake hazard studies in the northeastern United States. Tech. Rep. 98-01, Lamont Cooperative Seismic Network, Lamont-Doherty Earth Observatory of Columbia University, Palisades, NY.

Numerical Calculation and Exergy Equations of Spray Heat Exchanger Attached to a Main Fan Diffuser

NASA Astrophysics Data System (ADS)

Cui, H.; Wang, H.; Chen, S.

2015-04-01

In the present study, the energy depreciation rule of spray heat exchanger, which is attached to a main fan diffuser, is analyzed based on the second law of thermodynamics. Firstly, the exergy equations of the exchanger are deduced. The equations are numerically calculated by the fourth-order Runge-Kutta method, and the exergy destruction is quantitatively effected by the exchanger structure parameters, working fluid (polluted air, i.e., PA; sprayed water, i.e., SW) initial state parameters and the ambient reference parameters. The results are showed: (1) heat transfer is given priority to latent transfer at the bottom of the exchanger, and heat transfer of convection and is equivalent to that of condensation in the upper. (2) With the decrease of initial temperature of SW droplet, the decrease of PA velocity or the ambient reference temperature, and with the increase of a SW droplet size or initial PA temperature, exergy destruction both increase. (3) The exergy efficiency of the exchanger is 72.1 %. An approach to analyze the energy potential of the exchanger may be provided for engineering designs.

Characterization and Evaluation of Two Novel Fluorescent Sigma-2 Receptor Ligands as Proliferation Probes

PubMed Central

Zeng, Chenbo; Vangveravong, Suwanna; Jones, Lynne A.; Hyrc, Krzysztof; Chang, Katherine C.; Xu, Jinbin; Rothfuss, Justin M.; Goldberg, Mark P.; Hotchkiss, Richard S.; Mach, Robert H.

2015-01-01

We synthesized and characterized two novel fluorescent sigma-2 receptor selective ligands, SW120 and SW116, and evaluated these ligands as potential probes for imaging cell proliferation. Both ligands are highly selective for sigma-2 receptors versus sigma-1 receptors. SW120 and SW116 were internalized into MDA-MB-435 cells, and 50% of the maximum fluorescent intensity was reached in 11 and 24 minutes, respectively. In vitro studies showed that 50% of SW120 or SW116 washed out of cells in 1 hour. The internalization of SW120 was reduced ≈30% by phenylarsine oxide, an inhibitor of endocytosis, suggesting that sigma-2 ligands are internalized, in part, by an endocytotic pathway. Subcellular localization studies using confocal and two-photon microscopy showed that SW120 and SW116 partially colocalized with fluorescent markers of mitochondria, endoplasmic reticulum, lysosomes, and the plasma membrane, suggesting that sigma-2 receptors localized to the cytoplasmic organelles and plasma membrane. SW120 did not colocalize with the nuclear dye 4′,6-diamidino-2-phenylindole. In vivo studies showed that the uptake of SW120 in solid tumors and peripheral blood mononuclear cells of mice positively correlated with the expression level of the cell proliferation marker Ki-67, suggesting that sigma-2 fluorescent probes may be used to image cell proliferation in mice. PMID:22201533

77 FR 12792 - Inviting Applications for the Rural Economic Development Loan and Grant Program for Fiscal Year 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

... USDA Rural Development State Office, 1835 Black Lake Boulevard SW., Suite B, Olympia, WA 98512-5715... (Braille, large print, audiotape, etc.) should contact USDA's TARGET Center at (202) 720-2600 (voice and...

77 FR 55523 - 60-Day Notice of Proposed Information Collection: Application for Employment as a Locally...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-10

... . Mail: U.S. Department of State--SA-44, HR/OE, Suite 368, Attention: Caroline Cole, 301 4th Street SW... employment use the DS-0174 to apply for Mission- advertised positions throughout the world. Mission...

CERES FM-5 on the NPP Spacecraft: Continuing the Earth Radiation Budget Climate Data Record

NASA Technical Reports Server (NTRS)

Priestly, Kory; Smith, G. Louis

2009-01-01

The Clouds and the Earth's Radiant Energy System (CERES) Flight Model-5 (FM-5) instrument will fly on the NPOESS Preparatory Project (NPP) spacecraft, which has a launch-readiness date in June, 2010. This mission will continue the critical Earth Radiation Budget Climate Data Record (CDR) begun by the Earth Radiation Budget Experiment (ERBE) instruments in the mid 1980 s and continued by the CERES instruments currently flying on the EOS Terra and Aqua spacecraft. Ground calibrations have been completed for FM-5 and the instrument has been delivered for integration to the spacecraft Rigorous pre-launch ground calibration is performed on each CERES unit to achieve an accuracy goal of 1% for SW flux and 0.5% for outgoing LW flux. Any ground to flight or in-flight changes in radiometer response is monitored using a protocol employing both onboard and vicarious calibration sources and experiments. Recent studies of FM-1 through FM-4 data have shown that the SW response of space based broadband radiometers can change dramatically due to optical contamination. With these changes having most impact on optical response to blue-to UV radiance, where tungsten lamps are largely devoid of output, such changes are hard to monitor accurately using existing on-board sources. This paper outlines the lessons learned on the existing CERES sensors from 30+ years of flight experience and presents a radiometric protocol to be implemented on the FM-5 instrument to ensure that its performance exceeds the stated calibration and stability goals.

Reconstruction of secular variation in seawater sulfate concentrations

NASA Astrophysics Data System (ADS)

Algeo, T. J.; Luo, G. M.; Song, H. Y.; Lyons, T. W.; Canfield, D. E.

2015-04-01

Long-term secular variation in seawater sulfate concentrations ([SO42-]SW) is of interest owing to its relationship to the oxygenation history of Earth's surface environment. In this study, we develop two complementary approaches for quantification of sulfate concentrations in ancient seawater and test their application to late Neoproterozoic (635 Ma) to Recent marine units. The "rate method" is based on two measurable parameters of paleomarine systems: (1) the S-isotope fractionation associated with microbial sulfate reduction (MSR), as proxied by Δ34SCAS-PY, and (2) the maximum rate of change in seawater sulfate, as proxied by &partial; δ 34SCAS/∂ t(max). The "MSR-trend method" is based on the empirical relationship of Δ34SCAS-PY to aqueous sulfate concentrations in 81 modern depositional systems. For a given paleomarine system, the rate method yields an estimate of maximum possible [SO42-]SW (although results are dependent on assumptions regarding the pyrite burial flux, FPY), and the MSR-trend method yields an estimate of mean [SO42-]SW. An analysis of seawater sulfate concentrations since 635 Ma suggests that [SO42-]SW was low during the late Neoproterozoic (<5 mM), rose sharply across the Ediacaran-Cambrian boundary (~5-10 mM), and rose again during the Permian (~10-30 mM) to levels that have varied only slightly since 250 Ma. However, Phanerozoic seawater sulfate concentrations may have been drawn down to much lower levels (~1-4 mM) during short (<~2 Myr) intervals of the Cambrian, Early Triassic, Early Jurassic, and Cretaceous as a consequence of widespread ocean anoxia, intense MSR, and pyrite burial. The procedures developed in this study offer potential for future high-resolution quantitative analyses of paleo-seawater sulfate concentrations.

Multidisciplinary approach for fault detection: Integration of PS-InSAR, geomorphological, stratigraphic and structural data in the Venafro intermontane basin (Central-Southern Apennines, Italy)

NASA Astrophysics Data System (ADS)

Amato, Vincenzo; Aucelli, Pietro P. C.; Bellucci Sessa, Eliana; Cesarano, Massimo; Incontri, Pietro; Pappone, Gerardo; Valente, Ettore; Vilardo, Giuseppe

2017-04-01

A multidisciplinary methodology, integrating stratigraphic, geomorphological and structural data, combined with GIS-aided analysis and PS-InSAR interferometric data, was applied to characterize the relationships between ground deformations and the stratigraphic and the morphostructural setting of the Venafro intermontane basin. This basin is a morphostructural depression related to NW-SE and NE-SW oriented high angle normal faults bordering and crossing it. In particular, a well-known active fault crossing the plain is the Aquae Juliae Fault, whose recent activity is evidenced by archeoseismological data. The approach applied here reveals new evidence of possible faulting, acting during the Lower to Upper Pleistocene, which has driven the morphotectonic and the environmental evolution of the basin. In particular, the tectonic setting emerging from this study highlights the influence of the NW-SE oriented extensional phase during the late Lower Pleistocene - early Middle Pleistocene, in the generation of NE-SW trending, SE dipping, high-angle faults and NW-SE trending, high-angle transtensive faults. This phase has been followed by a NE-SW extensional one, responsible for the formation of NW-SE trending, both NW and SE dipping, high-angle normal faults, and the reactivation of the oldest NE-SW oriented structures. These NW-SE trending normal faults include the Aquae Juliae Fault and a new one, unknown until now, crossing the plain between the Venafro village and the Colle Cupone Mt. (hereinafter named the Venafro-Colle Cupone Fault, VCCF). This fault has controlled deposition of the youngest sedimentary units (late Middle Pleistocene to late Upper Pleistocene) suggesting its recent activity and it is well constrained by PS-InSAR data, as testified by the increase of the subsidence rate in the hanging wall block.

Optimized solar-wind-powered drip irrigation for farming in developing countries

NASA Astrophysics Data System (ADS)

Barreto, Carolina M.

The two billion people produce 80% of all food consumed in the developing world and 1.3 billion lack access to electricity. Agricultural production will have to increase by about 70% worldwide by 2050 and to achieve this about 50% more primary energy has to be made available by 2035. Energy-smart agri-food systems can improve productivity in the food sector, reduce energy poverty in rural areas and contribute to achieving food security and sustainable development. Agriculture can help reduce poverty for 75% of the world's poor, who live in rural areas and work mainly in farming. The costs associated with irrigation pumping are directly affected by energy prices and have a strong impact on farmer income. Solar-wind (SW) drip irrigation (DI) is a sustainable method to meet these challenges. This dissertation shows with onsite data the low cost of SW pumping technologies correlating the water consumption (evapotranspiration) and the water production (SW pumping). The author designed, installed, and collected operating data from the six SWDI systems in Peru and in the Tohono O'odham Nation in AZ. The author developed, tested, and a simplified model for solar engineers to size SWDI systems. The author developed a business concept to scale up the SWDI technology. The outcome was a simplified design approach for a DI system powered by low cost SW pumping systems optimized based on the logged on site data. The optimization showed that the SWDI system is an income generating technology and that by increasing the crop production per unit area, it allowed small farmers to pay for the system. The efficient system resulted in increased yields, sometimes three to four fold. The system is a model for smallholder agriculture in developing countries and can increase nutrition and greater incomes for the world's poor.

Solving the dynamic rupture problem with different numerical approaches and constitutive laws

USGS Publications Warehouse

Bizzarri, A.; Cocco, M.; Andrews, D.J.; Boschi, Enzo

2001-01-01

We study the dynamic initiation, propagation and arrest of a 2-D in-plane shear rupture by solving the elastodynamic equation by using both a boundary integral equation method and a finite difference approach. For both methods we adopt different constitutive laws: a slip-weakening (SW) law, with constant weakening rate, and rate- and state-dependent friction laws (Dieterich-Ruina). Our numerical procedures allow the use of heterogeneous distributions of constitutive parameters along the fault for both formulations. We first compare the two solution methods with an SW law, emphasizing the required stability conditions to achieve a good resolution of the cohesive zone and to avoid artificial complexity in the solutions. Our modelling results show that the two methods provide very similar time histories of dynamic source parameters. We point out that, if a careful control of resolution and stability is performed, the two methods yield identical solutions. We have also compared the rupture evolution resulting from an SW and a rate- and state-dependent friction law. This comparison shows that despite the different constitutive formulations, a similar behaviour is simulated during the rupture propagation and arrest. We also observe a crack tip bifurcation and a jump in rupture velocity (approaching the P-wave speed) with the Dieterich-Ruina (DR) law. The rupture arrest at a barrier (high strength zone) and the barrier-healing mechanism are also reproduced by this law. However, this constitutive formulation allows the simulation of a more general and complex variety of rupture behaviours. By assuming different heterogeneous distributions of the initial constitutive parameters, we are able to model a barrier-healing as well as a self-healing process. This result suggests that if the heterogeneity of the constitutive parameters is taken into account, the different healing mechanisms can be simulated. We also study the nucleation phase duration Tn, defined as the time necessary for the crack to reach the half-length Ic. We compare the Tn values resulting from distinct simulations calculated using different constitutive laws and different sets of constitutive parameters. Our results confirm that the DR law provides a different description of the nucleation process than the SW law adopted in this study. We emphasize that the DR law yields a complete description of the rupture process, which includes the most prominent features of SW.

SW-846 Method Style Guide

EPA Pesticide Factsheets

This style guide is for use by developers of new methods for SW-846 and editors of existing SW-846 methods. Its use will help assure consistent method format and minimize editorial errors during the development and maintenance of SW-846.

Influence of catalysts on co-combustion of sewage sludge and water hyacinth blends as determined by TG-MS analysis.

PubMed

Huang, Limao; Xie, Candie; Liu, Jingyong; Zhang, Xiaochun; Chang, KenLin; Kuo, Jiahong; Sun, Jian; Xie, Wuming; Zheng, Li; Sun, Shuiyu; Buyukada, Musa; Evrendilek, Fatih

2018-01-01

Effects of the three metal carbonates (K 2 CO 3 , Na 2 CO 3 , and MgCO 3 ) were quantified on catalytic co-combustion of the sewage sludge and water hyacinth (SW) blend using a thermogravimetric-mass spectrometric (TG-MS) analysis and kinetics modeling. The main dominating steps of the catalysts were the organic volatile matter release and combustion stage. Weighted mean values of activation energy (E m ) were estimated at 181.18KJ·mol -1 , 199.76KJ·mol -1 , 138.76KJ·mol -1 , and 177.88KJ·mol -1 for SW, SW+5% K 2 CO 3 , SW+5% Na 2 CO 3 , and SW+5% MgCO 3 , respectively. The lowest E m occurred with SW+5% Na 2 CO 3 . Overall, catalyst effect on co-combustion appeared to be negligible as indicated by Gibbs free energy (ΔG). The normalized intensities of SW+MgCO 3 were strongest. The addition of Na 2 CO 3 and MgCO 3 to SW increased flue gases emissions (CO 2 , NO 2 , SO 2 , HCN, and NH 3 ) of SW, whereas the addition of K 2 CO 3 to SW reduced flue gases emissions from the entire combustion process. Copyright © 2017 Elsevier Ltd. All rights reserved.

High dispersity of carbon nanotubes diminishes immunotoxicity in spleen.

PubMed

Lee, Soyoung; Khang, Dongwoo; Kim, Sang-Hyun

2015-01-01

From the various physiochemical material properties, the chemical functionalization order of single-walled carbon nanotubes (swCNTs) has not been considered as a critical factor for modulating immunological responses and toxicological aspects in drug delivery applications. Although most nanomaterials, including carbon nanotubes, are specifically accumulated in spleen, few studies have focused on spleen immunotoxicity. For this reason, this study demonstrated that the dispersity of swCNTs significantly influenced immunotoxicity in vitro and in vivo. For cytotoxicity of swCNTs, MTT assay, reactive oxygen species production, superoxide dismutase activity, cellular uptake, and confocal microscopy were used in macrophages. In the in vivo study, female BALB/c mice were intravenously administered with 1 mg/kg/day of swCNTs for 2 weeks. The body weight, organ weight, hematological change, reverse-transcription polymerase chain reaction, and lymphocyte population were evaluated. Different orders of chemical functionalization of swCNTs controlled immunotoxicity. In short, less-dispersed swCNTs caused cytotoxicity in macrophages and abnormalities in immune organs such as spleen, whereas highly dispersed swCNTs did not result in immunotoxicity. This study clarified that increasing carboxyl groups on swCNTs significantly mitigated immunotoxicity in vitro and in vivo. Our findings clarified the effective immunotoxicological factors of swCNTs by increasing dispersity of swCNTs and provided useful guidelines for the effective use of nanomaterials.

78 FR 33464 - Illinois Disaster Number IL-00041

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

... Loans): Bureau; Crawford; Henderson; Knox; Livingston; Marshall; Mason; Mcdonough; Peoria; Rock Island... the Presidential declaration of a major disaster for the State of Illinois (FEMA-4116-DR), dated 05/10... Street SW., Suite 6050, Washington, DC 20416. SUPPLEMENTARY INFORMATION: The notice of the Presidential...

78 FR 23262 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

... OMB Review; Comment Request Title: Descriptive Study of County versus State Administered Temporary... Children and Families (ACF) is proposing an information collection activity as part of the Descriptive... for Children and Families, Office of Planning, Research and Evaluation, 370 L'Enfant Promenade, SW...

77 FR 26231 - State of Tennessee; Underground Injection Control (UIC) Program Primacy

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-03

... public docket, visit the EPA Docket Center homepage at http://www.epa.gov/epahome/dockets.htm of the.... Environmental Protection Agency, Region 4, Library, 9th Floor, 61 Forsyth Street SW., Atlanta, Georgia 30303. The Library is open from [[Page 26232

Molecular mechanisms of the angiogenic effects of low-energy shock wave therapy: roles of mechanotransduction.

PubMed

Hatanaka, Kazuaki; Ito, Kenta; Shindo, Tomohiko; Kagaya, Yuta; Ogata, Tsuyoshi; Eguchi, Kumiko; Kurosawa, Ryo; Shimokawa, Hiroaki

2016-09-01

We have previously demonstrated that low-energy extracorporeal cardiac shock wave (SW) therapy improves myocardial ischemia through enhanced myocardial angiogenesis in a porcine model of chronic myocardial ischemia and in patients with refractory angina pectoris. However, the detailed molecular mechanisms for the SW-induced angiogenesis remain unclear. In this study, we thus examined the effects of SW irradiation on intracellular signaling pathways in vitro. Cultured human umbilical vein endothelial cells (HUVECs) were treated with 800 shots of low-energy SW (1 Hz at an energy level of 0.03 mJ/mm(2)). The SW therapy significantly upregulated mRNA expression and protein levels of vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (eNOS). The SW therapy also enhanced phosphorylation of extracellular signal-regulated kinase 1/2 (Erk1/2) and Akt. Furthermore, the SW therapy enhanced phosphorylation of caveolin-1 and the expression of HUTS-4 that represents β1-integrin activity. These results suggest that caveolin-1 and β1-integrin are involved in the SW-induced activation of angiogenic signaling pathways. To further examine the signaling pathways involved in the SW-induced angiogenesis, HUVECs were transfected with siRNA of either β1-integrin or caveolin-1. Knockdown of either caveolin-1 or β1-integrin suppressed the SW-induced phosphorylation of Erk1/2 and Akt and upregulation of VEGF and eNOS. Knockdown of either caveolin-1 or β1-integrin also suppressed SW-induced enhancement of HUVEC migration in scratch assay. These results suggest that activation of mechanosensors on cell membranes, such as caveolin-1 and β1-integrin, and subsequent phosphorylation of Erk and Akt may play pivotal roles in the SW-induced angiogenesis. Copyright © 2016 the American Physiological Society.

Validation of the SenseWear Mini activity monitor in 5-12-year-old children.

PubMed

van Loo, Christiana M T; Okely, Anthony D; Batterham, Marijka J; Hinkley, Trina; Ekelund, Ulf; Brage, Søren; Reilly, John J; Peoples, Gregory E; Jones, Rachel A; Janssen, Xanne; Cliff, Dylan P

2017-01-01

This study aimed to validate SenseWear Mini software algorithm versions 2.2 (SW2.2) and 5.2 (SW5.2) for estimating energy expenditure (EE) in children. Laboratory-based validation study. 57 children aged 5-12 y completed a protocol involving 15 semi-structured sedentary (SED), light-intensity (LPA), and moderate- to vigorous-intensity (MVPA) physical activities. EE was estimated using portable indirect calorimetry (IC). The accuracy of EE estimates (kcal·min -1 ) from SW2.2 and SW5.2 were examined at the group level and individual level using the mean absolute percentage error (MAPE), Bland-Altman plots and equivalence testing. MAPE values were lower for SW5.2 (30.1±10.7%) than for SW2.2 (44.0±6.2%). Although mean differences for SW5.2 were smaller than for SW2.2 during SED (-0.23±0.22 vs. -0.61±0.20kcal·min -1 ), LPA (-0.69±0.76 vs. -1.07±0.46kcal·min -1 ) and MVPA (-2.22±1.15 vs. -2.57±1.15kcal·min -1 ), limits of agreement did not decrease for the updated algorithms. For all activities, SW2.2 and SW5.2 were not equivalent to IC (p>0.05). Errors increased with increasing intensity. The current SenseWear Mini algorithms SW5.2 underestimated EE. The overall improved accuracy for SW5.2 was not accompanied with improved accuracy at the individual level and EE estimates were not equivalent to IC. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Properties of small instream wood as a logjam clogging agent: Implications for clogging dynamics based on wood density, water content, and depositional environment

NASA Astrophysics Data System (ADS)

Haga, Hirokazu; Moriishida, Takuya; Morishita, Naoya; Fujimoto, Takaaki

2017-11-01

In cooperation with large instream wood (LW) within logjams, small instream wood (SW) can control downstream flux of sediment and particulate organic matter and can play an important role for stream ecosystems. However, information regarding the density and moisture content of SW-which affects wood transport, wood decay, and mass loading-is limited. Here we investigated the SW properties, i.e., density under field conditions (in situ density), basic density, volumetric water content, and depositional environment of SW sampled from five logjams and their backwater areas in two headwater streams (second- and third-order streams) surrounded by mixed broadleaf-conifer forests in western Japan. The in situ density ranged from 0.49 to 1.25 g cm- 3, and pieces with densities > 1.0 g cm- 3 accounted for 45% of all samples. Additionally, the in situ density of SW closely related to the volumetric water content (r2 = 0.76) rather than the basic density as an index of solidity or decay condition of wood. The SW that was partially submerged in water had a higher volumetric water content than SW exposed to air. These results indicate that a nonfloating transport cannot be ignored as an important mechanism for SW movement and that in situ density depends not on the solidity of the wood but on water sorption by SW. However, waterlogged SW should be well decayed because it has a lower basic density than air-exposed and sediment-buried SW. We conclude that the moisture conditions of the depositional environment can affect subsequent transport and decay processes of SW. Moreover, most waterlogged and sediment-buried SW, because of its high in situ density (> 1.0 g cm- 3), may contribute to clogging between the channel bed and LW that initiate a logjam during future movements.

Spin-waves in thin films with Dzyaloshinskii-Moriya interaction

NASA Astrophysics Data System (ADS)

Diep, H. T.; El Hog, Sahbi; Puszkarski, Henryk

2018-05-01

Using the Green's function method, we calculate the spin-wave (SW) spectrum in a thin film with quantum Heisenberg spins interacting with each other via an exchange interaction J and a Dzyaloshinskii-Moriya interaction of magnitude D. Due to the competition between J and D, the ground state is non collinear. We show that for large D, the first mode in the SW spectrum is proportional to the in plane wave-vector k at the limit k tending to zero. For small D, it is proportional to k2. We show that the surface modes may occur depending on the surface exchange interaction. We calculate the layer magnetizations at temperature T and the transition temperature as a function of the film thickness.

Chandra Observations of the Solar System

NASA Astrophysics Data System (ADS)

Lisse, Carey

2014-11-01

Many solar system objects are now known to emit X-rays due to charge-exchange between highly charged solar wind (SW) minor ions and neutrals in their extended atmospheres, including Earth, Venus, Mars, Jupiter, and the heliosphere, with total power outputs on the MW - GW scale. (Currently only upper limits exist for Saturn and Pluto.) Chandra observations of their morphology, spectra, and time dependence provide important information about the neutral atmosphere structure and the SW flux and charge state. Chandra observations of solar x-ray scattering from Earth, Venus, Mars, Jupiter, Saturn, and the Moon have also provided important clues for the scattering material and the solar radiation field at the body. We present here a 15 year summary of Chandra's solar system observations.

Nanoneedle transistor-based sensors for the selective detection of intracellular calcium ions.

PubMed

Son, Donghee; Park, Sung Young; Kim, Byeongju; Koh, Jun Tae; Kim, Tae Hyun; An, Sangmin; Jang, Doyoung; Kim, Gyu Tae; Jhe, Wonho; Hong, Seunghun

2011-05-24

We developed a nanoneedle transistor-based sensor (NTS) for the selective detection of calcium ions inside a living cell. In this work, a single-walled carbon nanotube-based field effect transistor (swCNT-FET) was first fabricated at the end of a glass nanopipette and functionalized with Fluo-4-AM probe dye. The selective binding of calcium ions onto the dye molecules altered the charge state of the dye molecules, resulting in the change of the source-drain current of the swCNT-FET as well as the fluorescence intensity from the dye. We demonstrated the electrical and fluorescence detection of the concentration change of intracellular calcium ions inside a HeLa cell using the NTS.

The potential of intensity-modulated proton radiotherapy to reduce swallowing dysfunction in the treatment of head and neck cancer: A planning comparative study.

PubMed

van der Laan, Hans Paul; van de Water, Tara A; van Herpt, Heleen E; Christianen, Miranda E M C; Bijl, Hendrik P; Korevaar, Erik W; Rasch, Coen R; van 't Veld, Aart A; van der Schaaf, Arjen; Schilstra, Cornelis; Langendijk, Johannes A

2013-04-01

Predictive models for swallowing dysfunction were developed previously and showed the potential of improved intensity-modulated radiotherapy to reduce the risk of swallowing dysfunction. Still the risk is high. The aim of this study was to determine the potential of swallowing-sparing (SW) intensity-modulated proton therapy (IMPT) in head and neck cancer (HNC) for reducing the risk of swallowing dysfunction relative to currently used photon therapy. Twenty-five patients with oropharyngeal (n = 21) and hypopharyngeal (n = 4) cancer received primary radiotherapy, including bilateral neck irradiation, using standard (ST) intensity-modulated photon therapy (IMRT). Prophylactic (54 Gy) and therapeutic (70 Gy) target volumes were defined. The dose to the parotid and submandibular glands was reduced as much as possible. Four additional radiotherapy plans were created for each patient: SW-IMRT, ST-IMPT, 3-beam SW-IMPT (3B-SW-IMPT) and 7-beam SW-IMPT (7B-SW-IMPT). All plans were optimized similarly, with additional attempts to spare the swallowing organs at risk (SWOARs) in the SW plans. Probabilities of swallowing dysfunction were calculated with recently developed predictive models. All plans complied with standard HNC radiotherapy objectives. The mean parotid gland doses were similar for the ST and SW photon plans, but clearly lower in all IMPT plans (ipsilateral parotid gland ST-IMRT: 46 Gy, 7B-SW-IMPT: 29 Gy). The mean dose in the SWOARs was lowest with SW-IMPT, in particular with 7B-SW-IMPT (supraglottic larynx ST-IMRT: 60 Gy, 7B-SW-IMPT: 40 Gy). The observed dose reductions to the SWOARs translated into substantial overall reductions in normal tissue complication risks for different swallowing dysfunction endpoints. Compared with ST-IMRT, the risk of physician-rated grade 2-4 swallowing dysfunction was reduced on average by 8.8% (95% CI 6.5-11.1%) with SW-IMRT, and by 17.2% (95% CI: 12.7-21.7%) with 7B-SW-IMPT. SWOAR-sparing with proton therapy has the potential to substantially reduce the risk of swallowing dysfunction compared to similar treatment with photons.

The search for reliable aqueous solubility (Sw) and octanol-water partition coefficient (Kow) data for hydrophobic organic compounds; DDT and DDE as a case study

USGS Publications Warehouse

Pontolillo, James; Eganhouse, R.P.

2001-01-01

The accurate determination of an organic contaminant?s physico-chemical properties is essential for predicting its environmental impact and fate. Approximately 700 publications (1944?2001) were reviewed and all known aqueous solubilities (Sw) and octanol-water partition coefficients (Kow) for the organochlorine pesticide, DDT, and its persistent metabolite, DDE were compiled and examined. Two problems are evident with the available database: 1) egregious errors in reporting data and references, and 2) poor data quality and/or inadequate documentation of procedures. The published literature (particularly the collative literature such as compilation articles and handbooks) is characterized by a preponderance of unnecessary data duplication. Numerous data and citation errors are also present in the literature. The percentage of original Sw and Kow data in compilations has decreased with time, and in the most recent publications (1994?97) it composes only 6?26 percent of the reported data. The variability of original DDT/DDE Sw and Kow data spans 2?4 orders of magnitude, and there is little indication that the uncertainty in these properties has declined over the last 5 decades. A criteria-based evaluation of DDT/DDE Sw and Kow data sources shows that 95?100 percent of the database literature is of poor or unevaluatable quality. The accuracy and reliability of the vast majority of the data are unknown due to inadequate documentation of the methods of determination used by the authors. [For example, estimates of precision have been reported for only 20 percent of experimental Sw data and 10 percent of experimental Kow data.] Computational methods for estimating these parameters have been increasingly substituted for direct or indirect experimental determination despite the fact that the data used for model development and validation may be of unknown reliability. Because of the prevalence of errors, the lack of methodological documentation, and unsatisfactory data quality, the reliability of the DDT/ DDE Sw and Kow database is questionable. The nature and extent of the errors documented in this study are probably indicative of a more general problem in the literature of hydrophobic organic compounds. Under these circumstances, estimation of critical environmental parameters on the basis of Sw and Kow (for example, bioconcentration factors, equilibrium partition coefficients) is inadvisable because it will likely lead to incorrect environmental risk assessments. The current state of the database indicates that much greater efforts are needed to: 1) halt the proliferation of erroneous data and references, 2) initiate a coordinated program to develop improved methods of property determination, 3) establish and maintain consistent reporting requirements for physico-chemical property data, and 4) create a mechanism for archiving reliable data for widespread use in the scientific/regulatory community.

HESS Opinions "Integration of groundwater and surface water research: an interdisciplinary problem?"

NASA Astrophysics Data System (ADS)

Barthel, R.

2014-02-01

Today there is a great consensus that water resources research needs to become more holistic, integrating perspectives of a large variety of disciplines. Groundwater and surface water (hereafter: GW and SW) are typically identified as different compartments of the hydrological cycle and were traditionally often studied and managed separately. However, despite this separation, these respective fields of study are usually not considered to be different disciplines. They are often seen as different specialisations of hydrology with different focus, yet similar theory, concepts, methodology. The present article discusses how this notion may form a substantial obstacle in the further integration of GW and SW research and management. The article focusses on the regional scale (areas of approx. 103 to 106 km2), which is identified as the scale where integration is most greatly needed, but ironically the least amount of fully integrated research seems to be undertaken. The state of research on integrating GW and SW research is briefly reviewed and the most essential differences between GW hydrology (or hydrogeology, geohydrology) and SW hydrology are presented. Groundwater recharge and baseflow are used as examples to illustrate different perspectives on similar phenomena that can cause severe misunderstandings and errors in the conceptualisation of integration schemes. It is also discussed that integration of GW and SW research on the regional scale necessarily must move beyond the hydrological aspects, by collaborating with social sciences and increasing the interaction between science and the society in general. The typical elements of an ideal interdisciplinary workflow are presented and their relevance with respect to integration of GW and SW is discussed. The overall conclusions are that GW hydrology and SW hydrogeology study rather different objects of interest, using different types of observation, working on different problem settings. They have thus developed different theory, methodology and terminology. Yet, there seems to be a widespread lack of awareness of these differences which hinders the detection of the existing interdisciplinary aspects of GW and SW integration and consequently the development of truly unifying, interdisciplinary theory and methodology. Thus, despite having the ultimate goal of creating a more holistic approach, we should start integration by analysing potential disciplinary differences. Improved understanding among hydrologists of what interdisciplinary means and how it works is needed. Hydrologists, despite frequently being involved in multidisciplinary projects, are not sufficiently involved in developing interdisciplinary strategies and do usually not regard the process of integration as such as a research topic of its own. There seems to be a general reluctance to apply (truly) interdisciplinary methodology because this is tedious and few, immediate incentives are experienced.

The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis.

PubMed

Ebermann, Linda; Wika, Sylwia; Klumpe, Inga; Hammer, Elke; Klingel, Karin; Lassner, Dirk; Völker, Uwe; Erben, Ulrike; Zeichhardt, Heinz; Schultheiss, Heinz-Peter; Dörner, Andrea

2012-01-01

Well-established differences in Coxsackievirus B3 (CVB3) elimination in resistant C57BL/6 and permissive A.SW/SnJ mice provide suitable models for studying the significance of the link between mitochondrial respiratory chain (RC), antioxidative stress components and mitochondrion-related apoptosis in the context of myocardial virus elimination. Distinct myocardial CVB3 titer in C57BL/6 (2.5 ± 1.4 × 10(4) plaque-forming units (p.f.u.)/g tissue) and A.SW/SnJ mice (1.4 ± 0.8 × 10(7) p.f.u./g) were associated with differences in the cardiac mitochondrial function 8 days post infection (p.i.). Infected C57BL/6 mouse hearts disclosed increased complex I (CI) and CIII activity, but restricted CII and normal CIV activity of RC. Reduced expression of the antioxidative catalase was accompanied by elevated lipid peroxidation (LPO), indicating oxidative stress. Intrinsic apoptosis was activated demonstrated by elevated levels of Bax, Bcl-2, caspase 3 and DNA degradation. In contrast, all myocardial RC complex activities were restricted in CVB3-infected A.SW/SnJ mice. The antioxidative system provided sufficient protection against oxidative stress shown by an elevated catalase expression and unaltered LPO. Bax and Bcl-2 levels were unchanged in CVB3-infected A.SW/SnJ mice, while caspase 3 was moderately increased but no DNA degradation was detectable. Correlation analyses including data from the two mouse strains revealed that reduced CVB3 titer correlated with increased CI and CIII activity, oxidative stress as well as active apoptosis during acute myocarditis (MC). C57BL/6 mice completely eliminated CVB3 and inflammation and normalized all intracellular parameters, while A.SW/SnJ mice showed permanently restricted CI activity in chronic MC 90 days p.i., at which time the replicating virus was no longer detectable but immunological processes were still active. Consequently, the regulation of energy metabolism appears crucial for an effective virus elimination and may be of prognostic and therapeutic significance for patients with virus-induced MC.

Inhibition of N-linked oligosaccharide processing does not prevent the secretion of thyroglobulin. A study with swainsonine and deoxynojirimycin.

PubMed

Franc, J L; Hovsepian, S; Fayet, G; Bouchilloux, S

1986-05-15

The effects of two drugs, swainsonine (SW) and deoxynojirimycin (dNM), on synthesis and export of thyroglobulin were studied in folliculized porcine thyroid cells cultured in a serum-free medium. These drugs were expected to alter N-linked glycans in thyroglobulin. Newly synthesized thyroglobulin labeled with [2-3H]mannose or [4,5-3H]leucine was obtained by immunoprecipitation from the follicular contents, culture media and cell extracts; the first two compartments, containing secreted thyroglobulin, were sometimes analyzed together. Leucine incorporation was not inhibited by SW and only slightly by dNM. In contrast dNM strongly decreased mannose incorporation (by up to 50-75% at 1-3 mM). However after 16-h mannose labelings, SW and/or dNM at 2.5 microM and 3 mM respectively did not significantly modify the relative proportions of radioactive thyroglobulin in the above-mentioned compartments. Pronase glycopeptides prepared from these thyroglobulins were examined with respect to behaviour on concanavalin-A-Sepharose and position on Bio-Gel P-4. Oligosaccharides released by endoglucosaminidase H and with high affinity for the lectin, i.e. high-mannose and certain hybrids, were further characterized by various exoglycosidase treatments. Thyroglobulin from control cells displayed complex and high-mannose glycans comparable in size and proportion to those attributed to tissue-extracted porcine thyroglobulin. After treatment with SW (an inhibitor of alpha-mannosidase II), complex glycans were almost totally replaced by sialylated hybrid glycans. In contrast to this nearly total suppression, dNM (an inhibitor of the trimming glucosidases) caused only a 30% decrease in labeling of complex units and an about 50% increase in high-mannose glycans, covered to some degree by glucose. Finally a [3H]leucine pulse-chase study was performed on thyroglobulin secretion in the absence or presence of both SW and dNM. Though a slowdown was detectable in the first few hours, this study revealed no change in the long-term export of thyroglobulin.

Inhibitory Influence of Enterococcus faecium on the Propagation of Swine Influenza A Virus In Vitro

PubMed Central

Wang, Zhenya; Chai, Weidong; Burwinkel, Michael; Twardziok, Sven; Wrede, Paul; Palissa, Christiane; Esch, Bettina; Schmidt, Michael F. G.

2013-01-01

The control of infectious diseases such as swine influenza viruses (SwIV) plays an important role in food production both from the animal health and from the public health point of view. Probiotic microorganisms and other health improving food supplements have been given increasing attention in recent years, but, no information on the effects of probiotics on swine influenza virus is available. Here we address this question by assessing the inhibitory potential of the probiotic Enterococcus faecium NCIMB 10415 (E. faecium) on the replication of two porcine strains of influenza virus (H1N1 and H3N2 strain) in a continuous porcine macrophage cell line (3D4/21) and in MDBK cells. Cell cultures were treated with E. faecium at the non-toxic concentration of 1×106 CFU/ml in growth medium for 60 to 90 min before, during and after SwIV infection. After further incubation of cultures in probiotic-free growth medium, cell viability and virus propagation were determined at 48 h or 96 h post infection. The results obtained reveal an almost complete recovery of viability of SwIV infected cells and an inhibition of virus multiplication by up to four log units in the E. faecium treated cells. In both 3D4/21- and MDBK-cells a 60 min treatment with E. faecium stimulated nitric oxide (NO) release which is in line with published evidence for an antiviral function of NO. Furthermore, E. faecium caused a modified cellular expression of selected mediators of defence in 3D4-cells: while the expression of TNF-α, TLR-3 and IL-6 were decreased in the SwIV-infected and probiotic treated cells, IL-10 was found to be increased. Since we obtained experimental evidence for the direct adsorptive trapping of SwIV through E. faecium, this probiotic microorganism inhibits influenza viruses by at least two mechanisms, direct physical interaction and strengthening of innate defence at the cellular level. PMID:23308134

Airborne Quercus pollen in SW Spain: Identifying favourable conditions for atmospheric transport and potential source areas.

PubMed

Maya-Manzano, José María; Fernández-Rodríguez, Santiago; Smith, Matt; Tormo-Molina, Rafael; Reynolds, Andrew M; Silva-Palacios, Inmaculada; Gonzalo-Garijo, Ángela; Sadyś, Magdalena

2016-11-15

The pollen grains of Quercus spp. (oak trees) are allergenic. This study investigates airborne Quercus pollen in SW Spain with the aim identifying favourable conditions for atmospheric transport and potential sources areas. Two types of Quercus distribution maps were produced. Airborne Quercus pollen concentrations were measured at three sites located in the Extremadura region (SW Spain) for 3 consecutive years. The seasonal occurrence of Quercus pollen in the air was investigated, as well as days with pollen concentrations ≥80Pm(-3). The distance that Quercus pollen can be transported in appreciable numbers was calculated using clusters of back trajectories representing the air mass movement above the source areas (oak woodlands), and by using a state-of-the-art dispersion model. The two main potential sources of Quercus airborne pollen captured in SW Spain are Q. ilex subsp. ballota and Q. suber. The minimum distances between aerobiological stations and Quercus woodlands have been estimated as: 40km (Plasencia), 66km (Don Benito), 62km (Zafra) from the context of this study. Daily mean Quercus pollen concentration can exceed 1,700Pm(-3), levels reached not less than 24 days in a single year. High Quercus pollen concentration were mostly associated with moderate wind speed events (6-10ms(-1)), whereas that a high wind speed (16-20ms(-1)) seems to be associated with low concentrations. Copyright © 2016 Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galambos, Paul C.

This is the latest in a series of LDRD's that we have been conducting with Florida State University/Florida A&M University (FSU/FAMU) under the campus executive program. This research builds on the earlier projects; ''Development of Highly Integrated Magnetically and Electrostatically Actuated Micropumps'' (SAND2003-4674) and ''Development of Magnetically and Electrostatically Driven Surface Micromachined Pumps'' (SAND2002-0704P). In this year's LDRD we designed 2nd generation of surface micromachined (SMM) gear and viscous pumps. Two SUMMiT{trademark} modules full of design variations of these pumps were fabricated and one SwIFT{trademark} module is still in fabrication. The SwIFT{trademark} fabrication process results in a transparent pump housingmore » cover that will enable visualization inside the pumps. Since the SwIFT{trademark} pumps have not been tested as they are still in fabrication, this report will focus on the 2nd generation SUMMiT{trademark} designs. Pump testing (pressure vs. flow) was conducted on several of the SUMMiT{trademark} designs resulting in the first pump curve for this class of SMM pumps. A pump curve was generated for the higher torque 2nd generation gear pump designed by Jason Hendrix of FSU. The pump maximum flow rate at zero head was 6.5 nl/s for a 30V, 30 Hz square wave signal. This level of flow rate would be more than adequate for our typical SMM SUMMiT{trademark} or SwIFT{trademark} channels which have typical volumes on the order of 50 pl.« less

Exposure to swainsonine impairs adult neurogenesis and spatial learning and memory.

PubMed

Wang, Jiutao; Song, Lingzhen; Zhang, Qi; Zhang, Wei; An, Lei; Zhang, Yamei; Tong, Dewen; Zhao, Baoyu; Chen, Shulin; Zhao, Shanting

2015-01-05

Swainsonine (SW) is an indolizidine triol plant alkaloid isolated from the species Astragalus, colloquially termed locoweed. Ingestion induces severe neurological symptoms of livestock and wildlife, including ataxia, trembling, exaggerated fright reactions. Toxicity to the central and peripheral nervous system is caused by inhibition of lysosomal a-mannosidase (AMA) and accumulation of intracellular oligosaccharide. However, the effects of SW on adult neurogenesis and cognition have remained unclear. Therefore, the present study was conducted to examine the effects of SW on adult neurogenesis and learning as well as memory performance in adult mice. SW (10μg/mL in drinking water) was administered orally to mice for 4 weeks. Our results showed that SW reduced proliferation and survival of neural progenitor cells (NPCs) in culture, and in the hippocampus of adult mice. In addition, exposure to SW led to down-regulation of doublecortin (DCX) and synaptophysin (SYP) in the hippocampus. However, caspase 3 and glial fibrillary acidic protein (GFAP) levels were significantly increased in SW-treated mice. Finally, SW-treated mice exhibited deficits in hippocampus-dependent spatial learning and memory. Our findings suggest that SW affects adult neurogenesis and cognitive function. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Modeling & Testing of Inflatable Structures for Rapidly Deployable Port Infrastructures

DTIC Science & Technology

2010-07-01

Rapidly Deployable Port Infrastructures By: Andrew Bloxom Abel Medellin Chris Vince Dr. Solomon Yim N SW C C D -C IS D -2 01...Andrew Bloxom, Abel Medellin , Chris Vince, Dr. Solomon Yim 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...Andrew Bloxom Abel Medellin Chris Vince Dr. Solomon Yim A special thanks to: • Ben Testerman and Dr. Pat

Joint Force Quarterly. Issue 53, 2nd Quarter 2009

DTIC Science & Technology

2009-04-01

WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) National Defense University,260 Fifth Avenue, S.W. ( Building 64, Room 2505),Fort...improve the reader’s professional understand- ing or performance ? Speak to the implications from the operational to the strategic level of influence and...with building nuclear power plants. If this projection is accurate, significant energy dividends resulting from the nuclear agreement are unlikely

Tectonic evolution of the Neoproterozoic Tandilia sedimentary cover, Argentina: New evidence of contraction and extensional events in the southwest Gondwana margin

NASA Astrophysics Data System (ADS)

Hernández, Mariano; Arrouy, María Julia; Scivetti, Nicolás; Franzese, Juan R.; Canalicchio, José M.; Poiré, Daniel G.

2017-11-01

At the northwestern portion of the Tandilia System, a detailed structural analysis on the Precambrian sedimentary units exposed in the quarries of the Olavarría-Sierras Bayas area was carried out. These units exhibit deformational structures of several scales, from centimeters to hundreds of meters. The hundreds of meters scale involves E-W- and NW-SE-trending normal faults and NW-SE- and NE-SW-trending contractional folds. The centimeters to meters scale involves veins, joints, normal faults, shear fractures and stylolites, with a prevailing ∼ E-W to NW-SE trend. All these structures were formed by two major tectonic events. The first was the folding event at ∼580 Ma, with NNE-SSW to NE-SW and NW-SE direction of contraction. The second was the extensional faulting event, given by the widespread NNE-SSW-directed extension event during the Atlantic Ocean opening (Jurassic-Cretaceous). Both major events would have been controlled by the reactivation of basement anisotropies. These major tectonic events controlled the deformation of the Precambrian sedimentary cover of the Tandilia system, leading to an economically important aspect in the mining development of the Olavarría-Sierras Bayas area.

Defining biological assemblages (biotopes) of conservation interest in the submarine canyons of the South West Approaches (offshore United Kingdom) for use in marine habitat mapping

NASA Astrophysics Data System (ADS)

Davies, Jaime S.; Howell, Kerry L.; Stewart, Heather A.; Guinan, Janine; Golding, Neil

2014-06-01

In 2007, the upper part of a submarine canyon system located in water depths between 138 and 1165 m in the South West (SW) Approaches (North East Atlantic Ocean) was surveyed over a 2 week period. High-resolution multibeam echosounder data covering 1106 km2, and 44 ground-truthing video and image transects were acquired to characterise the biological assemblages of the canyons. The SW Approaches is an area of complex terrain, and intensive ground-truthing revealed the canyons to be dominated by soft sediment assemblages. A combination of multivariate analysis of seabed photographs (184-1059 m) and visual assessment of video ground-truthing identified 12 megabenthic assemblages (biotopes) at an appropriate scale to act as mapping units. Of these biotopes, 5 adhered to current definitions of habitats of conservation concern, 4 of which were classed as Vulnerable Marine Ecosystems. Some of the biotopes correspond to descriptions of communities from other megahabitat features (for example the continental shelf and seamounts), although it appears that the canyons host modified versions, possibly due to the inferred high rates of sedimentation in the canyons. Other biotopes described appear to be unique to canyon features, particularly the sea pen biotope consisting of Kophobelemnon stelliferum and cerianthids.

Seamustard (Undaria pinnatifida) Improves Growth, Immunity, Fatty Acid Profile and Reduces Cholesterol in Hanwoo Steers

PubMed Central

Hwang, J. A.; Islam, M. M.; Ahmed, S. T.; Mun, H. S.; Kim, G. M.; Kim, Y. J.; Yang, C. J.

2014-01-01

The study was designed to evaluate the effect of 2% seamustard (Undaria pinnatifida) by-product (SW) on growth performance, immunity, carcass characteristics, cholesterol content and fatty acid profile in Hanwoo steers. A total of 20 Hanwoo steers (ave. 22 months old; 619 kg body weight) were randomly assigned to control (basal diet) and 2% SW supplemented diet. Dietary SW supplementation significantly (p<0.05) improved average daily gain and gain:feed ratio as well as serum immunoglobulin G concentration. Chemical composition and quality grade of meat and carcass yield grades evaluated at the end of the trial were found to be unaffected by SW supplementation. Dietary SW significantly reduced meat cholesterol concentration (p<0.05). Dietary SW supplementation significantly reduced the myristic acid (C14:0) and palmitoleic acid (C16:ln-7) concentration, while SW increased the concentration of stearic acid (C18:0) and linolenic acid (C18:3n-3) compared to control (p<0.05). Dietary SW supplementation had no effect on saturated fatty acids (SFA), unsaturated fatty acids, poly unsaturated fatty acid (PUFA) or mono unsaturated fatty acid content in muscles. A reduced ratio of PUFA/SFA and n-6/n-3 were found in SW supplemented group (p<0.05). In conclusion, 2% SW supplementation was found to improve growth, immunity and fatty acid profile with significantly reduced cholesterol of beef. PMID:25083105

Sedimentary record of sub-glacial outburst floods at Laurentian Fan

NASA Astrophysics Data System (ADS)

Leng, Wei; von Dobeneck, Tilo

2016-04-01

Large-scale glacial meltwater discharge could be widely recognized off the eastern Canadian continental margin. At Laurentian Fan, sub-glacial outburst floods eroded Permian-Carboniferous redbeds at Gulf of St. Lawrence and then delivered the reddish sediments by Laurentian Channel. Sedimentary record from four gravity cores (GeoB18514-2, 18515-1, 18516-2 and 18517-1) at the SW slope of the Grand Banks of Newfoundland revealed the major depositional processes since Heinrich event 2 (ca. 22 ka). In the cores, the upper thick Holocene olive-grey silty mud units overly IRD-rich Heinrich 1 layer, five reddish units are distinguished in the lower part. Reddish units get proportionally thinner along the SW slope at higher and more distal positions; instead, separating olive-grey layers get thicker with height and distance. Reddish and olive grey units have sharp boundaries and no signs of erosion. Mean grain size changes abruptly from coarse in grey layers to fine in reddish layers, terrigenous elements (as Al, K, Ti, Fe) and clays (Al/Si) are highly elevated in reddish layers and low in Heinrich layers, which are instead enriched in detrital continental carbonates. Both Heinrich layers and reddish layers have enhanced magnetic susceptibility, but Heinrich layer have higher ferromagnetic (SIRM) content (mafic rocks), while reddish layers have more hematite (HIRM). These five reddish layers differ from event to event, which seems to reflect different mixing ratios of event-related and background sedimentation. This mixing will allow estimating event-specific sedimentation rates. Using mixing ratio combined with 14C dating data could contribute to estimate the sedimentation rate and duration of outburst floods, which could help to build ice sheet retreat history and find the connection with paleoclimate changes.

Geochemistry and tectonostratigraphy of the basal allochthonous units of SW Iberia (Évora Massif, Portugal): Keys to the reconstruction of pre-Pangean paleogeography in southern Europe

NASA Astrophysics Data System (ADS)

Fernández, Rubén Díez; Fuenlabrada, José Manuel; Chichorro, Martim; Pereira, M. Francisco; Sánchez-Martínez, Sonia; Silva, José B.; Arenas, Ricardo

2017-01-01

The basal allochthonous units of NW and SW Iberia are members of an intra-Gondwana suture zone that spreads across the Iberian Massif and was formed during the collision of Gondwana and Laurussia in the late Paleozoic. This suture zone is made of allochthonous terranes and is currently preserved as a tectonically dismembered ensemble. A multi-proxy analysis is applied to the basal allochthonous units of Iberia to test their affinity and potential usage for tracing a suture zone. A comparison of the lithostratigraphy, tectonometamorphic evolution, geochronology, and geochemical characteristics of the Ediacaran series of these units reveals striking affinities. They derive from rather similar immature sedimentary successions, deposited along the same continental margin, and in relation to a Cadomian magmatic arc. Sm-Nd systematics indicates that the isotopic sources are among the oldest of the Iberian Massif (ca. 2.15-1.5 Ga), suggesting a very strong contribution from the West African Craton. These Ediacaran series were affected by high-P and low- to medium-T metamorphism (blueschist to eclogite facies) during the Late Devonian (ca. 370 Ma). They occur below allochthonous ophiolitic sequences, and on top of autochthonous or parautochthonous domains lacking of high-P and low- to medium-T Devonian metamorphism, i.e., tectonically sandwiched between lithosphere-scale thrusts. The combination of all these characteristics makes these particular Ediacaran series different from the rest of the terranes of the Iberian Massif. Such singularity could be useful for tracing more occurrences of the same suture zone along the Variscan orogen, particularly in cases where its preservation and recognition may be cryptic. It also contributes to improve the paleogeographic reconstruction of the margin of Gondwana during the Ediacaran.

Fore arc tectonothermal evolution of the El Oro metamorphic province (Ecuador) during the Mesozoic

NASA Astrophysics Data System (ADS)

Riel, Nicolas; Martelat, Jean-Emmanuel; Guillot, Stéphane; Jaillard, Etienne; Monié, Patrick; Yuquilema, Jonatan; Duclaux, Guillaume; Mercier, Jonathan

2014-10-01

The El Oro metamorphic province of SW Ecuador is a composite massif made of juxtaposed terranes of both continental and oceanic affinity that has been located in a fore-arc position since Late Paleozoic times. Various geochemical, geochronological, and metamorphic studies have been undertaken on the El Oro metamorphic province, providing an understanding of the origin and age of the distinct units. However, the internal structures and geodynamic evolution of this area remain poorly understood. Our structural analysis and thermal modeling in the El Oro metamorphic province show that this fore-arc zone underwent four main geological events. (1) During Triassic times (230-225 Ma), the emplacement of the Piedras gabbroic unit at crustal-root level ( 9 kbar) triggered partial melting of the metasedimentary sequence under an E-W extensional regime at pressure-temperature conditions ranging from 4.5 to 8.5 kbar and from 650 to 900°C for the migmatitic unit. (2) At 226 Ma, the tectonic underplating of the Arenillas-Panupalí oceanic unit (9 kbar and 300°C) thermally sealed the fore-arc region. (3) Around the Jurassic-Cretaceous boundary, the shift from trench-normal to trench-parallel subduction triggered the exhumation and underplating of the high-pressure, oceanic Raspas Ophiolitic Complex (18 kbar and 600°C) beneath the El Oro Group (130-120 Ma). This was followed by the opening of a NE-SW pull-apart basin, which tilted the massif along an E-W subhorizontal axis (110 Ma). (4) In Late Cretaceous times, an N-S compressional event generated heterogeneous deformation due to the presence of the Cretaceous Celica volcanic arc, which acted as a buttress and predominantly affected the central and eastern part of the massif.

Curcumin and Viscum album Extract Decrease Proliferation and Cell Viability of Soft-Tissue Sarcoma Cells: An In Vitro Analysis of Eight Cell Lines Using Real-Time Monitoring and Colorimetric Assays.

PubMed

Harati, K; Behr, B; Daigeler, A; Hirsch, T; Jacobsen, F; Renner, M; Harati, A; Wallner, C; Lehnhardt, M; Becerikli, M

2017-01-01

The cytostatic effects of the polyphenol curcumin and Viscum album extract (VAE) were assessed in soft-tissue sarcoma (STS) cells. Eight human STS cell lines were used: fibrosarcoma (HT1080), liposarcoma (SW872, T778, MLS-402), synovial sarcoma (SW982, SYO1, 1273), and malignant fibrous histiocytoma (U2197). Primary human fibroblasts served as control cells. Cell proliferation, viability, and cell index (CI) were analyzed by BrdU assay, MTT assay, and real-time cell analysis (RTCA). As indicated by BrdU and MTT, curcumin significantly decreased the cell proliferation of five cell lines (HT1080, SW872, SYO1, 1273, and U2197) and the viability of two cell lines (SW872 and SW982). VAE led to significant decreases of proliferation in eight cell lines (HT1080, SW872, T778, MLS-402, SW982, SYO1, 1293, and U2197) and reduced viability in seven STS lines (HT1080, SW872, T778, MLS-402, SW982, SYO1, and 1273). As indicated by RTCA for 160 h, curcumin decreased the CI of all synovial sarcoma cell lines as well as T778 and HT1080. VAE diminished the CI in most of the synovial sarcoma (SW982, SYO1) and liposarcoma (SW872, T778) cell lines as well as HT1080. Primary fibroblasts were not affected adversely by the two compounds in RTCA. Curcumin and VAE can inhibit the proliferation and viability of STS cells.

The Image of Medieval Woman

ERIC Educational Resources Information Center

Wade, Marjorie D.

1978-01-01

California State University offered a course concerning the roles and positions of women in medieval society as depicted in Middle High German literature. The course was open to all undergraduate students and required no prerequisites or knowledge of German. The content and structure of the course are outlined. (SW)

50 CFR 85.21 - Application procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Division of Federal Aid, U.S. Fish and Wildlife Service, P.O. Box 1306, 500 Gold Avenue SW., Albuquerque... Region 6 States Include—Colorado, Kansas, Montana, North Dakota, Nebraska, South Dakota, Utah, and..., Denver, Colorado 80225 134 Union Boulevard, third floor, Lakewood, Colorado 80225, (303) 236-7392 Region...

50 CFR 85.21 - Application procedures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Division of Federal Aid, U.S. Fish and Wildlife Service, P.O. Box 1306, 500 Gold Avenue SW., Albuquerque... Region 6 States Include—Colorado, Kansas, Montana, North Dakota, Nebraska, South Dakota, Utah, and..., Denver, Colorado 80225 134 Union Boulevard, third floor, Lakewood, Colorado 80225, (303) 236-7392 Region...

50 CFR 85.21 - Application procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Division of Federal Aid, U.S. Fish and Wildlife Service, P.O. Box 1306, 500 Gold Avenue SW., Albuquerque... Region 6 States Include—Colorado, Kansas, Montana, North Dakota, Nebraska, South Dakota, Utah, and..., Denver, Colorado 80225 134 Union Boulevard, third floor, Lakewood, Colorado 80225, (303) 236-7392 Region...

Model for Steady-State Combustion of Unimodal Composite Solid Propellants.

DTIC Science & Technology

1978-01-01

Research and Technology Div.do= * 5390 Cherokee Avenue Alexandria, Virginia 22314 Cw* Contract F49620-78-C-0016 Air Force Office of Scientific Research ...owmaretgli w SW MODEL FOR STEADY-STATE COMBUSTION OF UNIMODAL COMPOSITE SOLID PROPELLANTS* Dr. Merrill K. Kingk* Atlantic Research Corporation...this country today) for pre- model, all flames are considered to occur in flame sheets at discrete distances from the * Research sponsored by the Air

Real time observation of the excimer formation dynamics of a gas phase benzene dimer by picosecond pump-probe spectroscopy.

PubMed

Miyazaki, Mitsuhiko; Fujii, Masaaki

2015-10-21

We observed the real-time excimer (EXC) formation dynamics of a gas phase benzene dimer (Bz2) cluster after photo-excitation to the S1 state by applying an ionization detected picosecond transient absorption method for probing the visible EXC absorption for the first time. The time evolution of the EXC absorption from the S1 0(0) level shows a rise that is well fitted by a single exponential function with a time constant of 18 ± 2 ps. The structure of the Bz dimer has a T-shaped structure in the ground electronic state, and that in the EXC state is a parallel sandwich (SW) structure. Thus, the observed rise time corresponds to the structural change from the T to the SW structures, which directly shows the EXC formation. On the other hand, the EXC formation after excitation of the S1 6(1) vibrational level of the stem site showed a faster rise of the time constant of 10 ± 2 ps. Supposing equilibrium between the EXC and the local excited states, it followed that the intramolecular vibrational energy redistribution rate of the 6(1) level is largely enhanced and becomes faster than the EXC formation reaction.

Proposed Navy Software Acquisition Improvement Strategy

DTIC Science & Technology

2009-03-16

Production and Deployment Operations and Support PRR IOC FOC OTRR DoD/ASN/RDA Policies Call for Gov’t SMEs to Define System Req’s, Support Milestone Reviews...of the SW; but with Gov’t Software SME oversight and insight W o A B C 12 Statement A: Approved for Public Release; Distribution is Unlimited 12...Comp, Segment levels is not sufficient to ensure & meet OA goalsSegment Level CSCIs CSCs Level of De SW CSCI 2 SW CSCI 1 SW CSCI ### Gov’t SW SMEs

Molecular dynamics growth modeling of InAs1-xSbx-based type-II superlattice

NASA Astrophysics Data System (ADS)

Ciani, Anthony J.; Grein, Christoph H.; Irick, Barry; Miao, Maosheng; Kioussis, Nicholas

2017-09-01

Type-II strained-layer superlattices (T2SL) based on InAs1-xSbx are a promising photovoltaic detector material technology for thermal imaging; however, Shockley-Read-Hall recombination and generation rates are still too high for thermal imagers based on InAs1-xSbx T2SL to reach their ideal performance. Molecular dynamics simulations using the Stillinger-Weber (SW) empirical potentials are a useful tool to study the growth of tetrahedral coordinated crystals and the nonequilibrium formation of defects within them, including the long-range effects of strain. SW potentials for the possible atomic interactions among {Ga, In, As, Sb} were developed by fitting to ab initio calculations of elastically distorted zinc blende and diamond unit cells. The SW potentials were tested against experimental observations of molecular beam epitaxial (MBE) growth and then used to simulate the MBE growth of InAs/InAs0.5Sb0.5 T2SL on GaSb substrates over a range of processes parameters. The simulations showed and helped to explain Sb cross-incorporation into the InAs T2SL layers, Sb segregation within the InAsSb layers, and identified medium-range defect clusters involving interstitials and their induction of interstitial-vacancy pairs. Defect formation was also found to be affected by growth temperature and flux stoichiometry.

Solar-wind proton access deep into the near-Moon wake

NASA Astrophysics Data System (ADS)

Nishino, M. N.; Fujimoto, M.; Maezawa, K.; Saito, Y.; Yokota, S.; Asamura, K.; Tanaka, T.; Tsunakawa, H.; Matsushima, M.; Takahashi, F.; Terasawa, T.; Shibuya, H.; Shimizu, H.

2009-08-01

We study solar wind (SW) entry deep into the near-Moon wake using SELENE (KAGUYA) data. It has been known that SW protons flowing around the Moon access the central region of the distant lunar wake, while their intrusion deep into the near-Moon wake has never been expected. We show that SW protons sneak into the deepest lunar wake (anti-subsolar region at ˜100 km altitude), and that the entry yields strong asymmetry of the near-Moon wake environment. Particle trajectory calculations demonstrate that these SW protons are once scattered at the lunar dayside surface, picked-up by the SW motional electric field, and finally sneak into the deepest wake. Our results mean that the SW protons scattered at the lunar dayside surface and coming into the night side region are crucial for plasma environment in the wake, suggesting absorption of ambient SW electrons into the wake to maintain quasi-neutrality.

Mass loading in the solar wind interaction with Venus and Mars

NASA Astrophysics Data System (ADS)

Breus, T. K.; Bauer, S. J.; Krymskii, A. M.; Mitnitskii, V. Ya.

1989-03-01

An analysis of available experimental data and theoretical concepts indicates that the interaction of the solar wind (SW) on the subsolar side with Venus, which has no intrinsic magnetic field, and with Mars, which has a small intrinsic magnetic field, is determined by the solar wind dynamic pressure with a contribution from the neutral planetary atmosphere to this interaction. The pattern of the SW interaction with these planets is different in principle for high and low dynamic pressures of the SW and is related to the varying intensity of ion formation processes (the SW Mass loading effect) in the vicinity of the SW obstacle boundary, which moves for different SW dynamic pressures into regions of different neutral atmosphere density. For moderate or high SW dynamic pressures, the subsolar Martian magnetosphere is also affected by this process. Results of numerical simulations of the SW-Mars interaction for a magnetospheric obstacle boundary at an altitude of 300 km are presented. To estimate the relative role of photoionization and charge exchange processes and their effect on the shock front position, different versions of the mass loading effect were separately calculated.

Osmoregulation and salt gland Na, K-ATPase activity following exposure to the anticholinesterase fenthion

USGS Publications Warehouse

Rattner, B.A.; Fleming, W.J.; Murray, H.C.

1982-01-01

Salt gland function and osmoregulation in aquatic birds drinking hyperosmotic water has been suggested to be impaired by organophosphorus insecticides. To test this hypothesis, adult ducks (Anas rubripes) were provided various regimens of fresh or salt (1.5% NaCl) water (FW, SW) and mash containing vehicle or 21 ppm fenthion (Fn) on days 1-7 and 7-12 of this study. The 8 treatments (day 1-7:day 7-12) included :FW:FW, FW:FW+Fn, FW:SW, FW+Fn:SW, FW:SW+Fn, FW+Fn:SW+FN, SW;SW, and SW:5W+Fn. Ducks were bled by jugular venipuncture on days 1,7 and 12, and then sacrificed. Brain and salt gland acetylcholinesterase activities were substantially inhibited (44-52% and 14-26%) by Fn. However, plasma Na, Cl and osmolality, as indirect but cumulative indices of salt gland function, were uniformly elevated in all SW groups including those receiving Fn. In a second experiment, salt gland Na,K-ATPase activity was reduced after in vitro incubation with DDE (40 and 400 ?M; positive control), but was unaffected by Fn and its oxygen analog (0.04-400 ?M). The present findings suggest that environmentally realistic concentrations of organophosphorus insecticides do not affect osmoregulatory function in adult ducks.

Why stones break better at slow shock wave rate than at fast rate: In vitro study with a research electrohydraulic lithotripter

PubMed Central

Pishchalnikov, Yuri A.; McAteer, James A.; Williams, James C.; Pishchalnikova, Irina V.; VonDerHaar, R. Jason

2008-01-01

Purpose Stones break better when the rate of shock wave (SW) delivery is slowed. It has been hypothesized that increased cavitation at fast rate shields pulse propagation, interfering with the delivery of SW energy to the stone. We tested this idea by correlating waveforms measured at the SW focus with cavitation viewed using high-speed imaging. Methods U30-gypsum stones held in a 2 mm-mesh basket were exposed to 200SWs at 30 or 120SW/min from a research electrohydraulic lithotripter (HM3-clone). Waveforms were collected using a fiberoptic probe hydrophone. High-speed imaging was used to observe cavitation bubbles in the water and at the stone surface. Results Stone breakage was significantly better at 30SW/min than at 120SW/min. Rate had little effect on SW parameters in the water free field. In the presence of particulates released from stones, the positive pressure of the SW remained unaffected, but the trailing tensile phase of the pulse was significantly reduced at 120SW/min. Conclusions Cavitation bubbles do not persist between SWs. Thus, mature bubbles from one pulse do not interfere with the next pulse, even at 120SW/min. However, cavitation nuclei carried by fine particles released from stones can persist between pulses. These nuclei have little effect on the compressive wave, but seed cavitation under influence of the tensile wave. Bubble growth draws energy from the negative-pressure phase of the SW, reducing its amplitude. This likely affects the dynamics of cavitation bubble clusters at the stone surface, reducing the effectiveness of bubble action in stone comminution. PMID:16903810

Simultaneous recording of multifocal VEP responses to short-wavelength and achromatic stimuli

PubMed Central

Wang, Min; Hood, Donald C.

2010-01-01

A paradigm is introduced that allows for simultaneous recording of the pattern-onset multifocal visual evoked potentials (mfVEP) to both short-wavelength (SW) and achromatic (A) stimuli. There were 5 sets of stimulus conditions, each of which is defined by two semi-concurrently presented stimuli, A64/SW (a 64% contrast achromatic stimulus and a short-wavelength stimulus), A64/A8 (64% achromatic/8% achromatic), A0/A8 (0% (gray) achromatic/8% achromatic), A64/A0 and A0/SW. When paired with A64 as part of A64/SW, the SW stimulus yielded mfVEP responses (SWmfVEP) with diminished amplitude in the fovea, consistent with the known sensitivity of the S-cone system. In addition, when A8, which is approximately equal to the L and M cone contribution of the SW stimulus, was recorded alone, the response to A8 was small, but significantly larger than noise. However, when A8 was paired with A64, the response to A8 was reduced to close to noise level, suggesting that the LM cone contribution of the SWmfVEP can be suppressed by A64. When A64 was recorded alone, the response to A64 was about 32% larger than the mfVEP for A64 when paired with the SW. Likewise, the presence of A64 stimulus also reduces the response of SWmfVEP by 35%. Finally, an intense narrow-band yellow background prolonged the latency of SW response for the A0/SW stimulus but not the latency of SW response for the A64/SW stimulus. These results indicate that it is possible to simultaneously record an SWmfVEP with little LM cone contribution along with an achromatic mfVEP. PMID:20499134

Validation of SenseWear Armband in children, adolescents, and adults.

PubMed

Lopez, G A; Brønd, J C; Andersen, L B; Dencker, M; Arvidsson, D

2018-02-01

SenseWear Armband (SW) is a multisensor monitor to assess physical activity and energy expenditure. Its prediction algorithms have been updated periodically. The aim was to validate SW in children, adolescents, and adults. The most recent SW algorithm 5.2 (SW5.2) and the previous version 2.2 (SW2.2) were evaluated for estimation of energy expenditure during semi-structured activities in 35 children, 31 adolescents, and 36 adults with indirect calorimetry as reference. Energy expenditure estimated from waist-worn ActiGraph GT3X+ data (AG) was used for comparison. Improvements in measurement errors were demonstrated with SW5.2 compared to SW2.2, especially in children and for biking. The overall mean absolute percent error with SW5.2 was 24% in children, 23% in adolescents, and 20% in adults. The error was larger for sitting and standing (23%-32%) and for basketball and biking (19%-35%), compared to walking and running (8%-20%). The overall mean absolute error with AG was 28% in children, 22% in adolescents, and 28% in adults. The absolute percent error for biking was 32%-74% with AG. In general, SW and AG underestimated energy expenditure. However, both methods demonstrated a proportional bias, with increasing underestimation for increasing energy expenditure level, in addition to the large individual error. SW provides measures of energy expenditure level with similar accuracy in children, adolescents, and adults with the improvements in the updated algorithms. Although SW captures biking better than AG, these methods share remaining measurements errors requiring further improvements for accurate measures of physical activity and energy expenditure in clinical and epidemiological research. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Dosimetric properties of a Solid Water High Equivalency (SW557) phantom for megavoltage photon beams.

PubMed

Araki, Fujio

2017-07-01

The dosimetric properties of the recently developed SW557 phantom have been investigated by comparison with those of the existing SW457 phantom in megavoltage photon beams. The electron fluence ratio φ pl w , and chamber ionization ratio k pl , of water to SW457 and water to SW557 for 4-15MV photons were calculated as a function of depth using Monte Carlo simulations, and compared with measured values. Values of φ pl w for SW457 were in the range of 1.004-1.014 for 4MV, and 1.014-1.018 for 15MV photons. The φ pl w for SW557 ranged from 1.005 to 1.008 for 4MV and from 1.010 to 1.015 for 15MV photons and the variation of φ pl w with depth for each beam energy was within ±0.5%. Values of k pl were obtained with a PTW 30013 Farmer-type ionization chamber. The k pl for SW457 ranged from 0.997 to 1.011 for 4-15MV photons. Values of k pl for SW557 were almost unity for 4 and 6MV photons, while in the case of 10 and 15MV photons they were less than 1.006, excepting the build-up region. The measured and calculated k pl values of water to SW557 were in the range of 0.997-1.002 and 1.000-1.006, respectively, for 4-15MV photons, at a depth of 10cm with a source-to-axis distance of 100cm. The measured and calculated k pl values were in agreement within their uncertainty ranges. As a water-equivalent phantom, SW557 can be used with a dosimetric difference within±0.6%, for 4-15MV photons, and is more water-equivalent than SW457 in megavoltage photon beams. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

77 FR 74472 - Notice of Availability of the Final Tank Closure and Waste Management Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-14

... Rooms Gonzaga University, Foley Center Library, 101-L East 502 Boone, Spokane, Washington 99258, (509) 313-5931. Portland State University, Government Information, Branford Price Millar Library, 1875 SW Park Avenue, Portland, Oregon 97201, (503) 725- 5874. University of Washington, Suzzallo-Allen Library...

77 FR 68795 - Protected Critical Infrastructure Information (PCII) Office Self-Assessment Questionnaire

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

...), Office of Infrastructure Protection (IP), Infrastructure Information Collection Division (IICD... forwarded to DHS/NPPD/IP/IICD, 245 Murray Lane, SW., Mail Stop 0602, Arlington,VA 20598-0602. Emailed.../IP PCII Program to assess state and local programs, their compliance with PCII rules and requirements...

Patterns of Specific Infant Behavior Interpretation.

ERIC Educational Resources Information Center

Baird, Samera Major; And Others

1995-01-01

Mothers viewed videotapes of interaction with their 20 full-term healthy, 20 preterm healthy, and 20 preterm sick infants between 11 and 26 weeks of age. Relationships between infant gazing, laughing, and fussing and maternal interpretation of emotional state, attention preference, attention curiosity, and physical needs were analyzed. (Author/SW)

Airport Activity Statistics of Certificated Route Air Carriers, 1992

DTIC Science & Technology

1992-12-31

PERWFE STATE ON US. AREA TYPE OF DEPARTURES CO CARR OPERAllON" AMCRT S UN A SHEDULEDAIMPMF mN SNAMUU SW SCHEOUUED NEW YOK- CAMu NEW YORK--C•n•tnw (LA...20,727 21 20.748 21,163 JACKSWONVILLECAMP LEJEUNE ( ALBERT J ELLIS) ......................................... US--U.S. AIR

77 FR 36213 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

...-0630; Directorate Identifier 2011-SW-010-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France EC130B4 helicopters... unsafe condition for the Eurocopter France EC130B4 helicopters. EASA states that it received reports that...

50 CFR 84.21 - How do I apply for a National Coastal Wetlands Conservation Grant?

Code of Federal Regulations, 2012 CFR

2012-10-01

... this process. (3) Send your proposals to the appropriate Regional Offices, as follows: Coastal states... and Wildlife Service, P.O. Box 1306, 500 Gold Avenue, SW, Albuquerque, New Mexico 87103, (505) 248-7450. Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin (Region 3) Regional Director...

Litho-structural analysis of eastern part of Ilesha schist belt, Southwestern Nigeria

NASA Astrophysics Data System (ADS)

Fagbohun, Babatunde Joseph; Adeoti, Blessing; Aladejana, Olabanji Odunayo

2017-09-01

The Ilesha schist belt is an excellent example of high strain shear belt within basement complex of southwestern Nigeria which is part of the larger West African Shield. The Ilesha schist belt is characterised by metasediment-metavolcanic, migmatite-gneiss and older granite rocks and the occurrence of a Shear zone which has been traced to and correlated with the central Hoggar Neoproterozoic shear zone as part of the Trans-Saharan Belt. Although the area is interesting in terms of geologic-tectonic setting, however, detailed geological assessment and structural interpretation of features in this area is lacking due accessibility problem. For these reasons we applied principal component analysis (PCA) and band ratio (BR) techniques on Landsat 8 OLI data for lithological discrimination while for structural interpretation, filtering techniques of edge enhancement and edge detection was applied on digital elevation model (DEM) acquired by shuttle radar topographic mission (SRTM) sensor. The PCA outperform BR for discrimination between quartzite and granite which are the most exposed rock units in the area. For structural interpretation, DEM was used to generate shaded relief model and edge maps which enable detailed structural interpretation. Geologic fieldwork was further conducted to validate structures and units identified from image processing. Based image interpretation, three deformation events were identified. The first event (D1) which is majorly a ductile deformation produced foliations and folds whose axial planes trend in NNE-SSW. The second event (D2) resulted in reactivation and rotation of the D1 structures particularly the folds in the NE-SW. The third event (D3) produced a transgressive deformation starting with the ductile deformation resulting in the development of sigmoidal structures oriented in NE-SW to E-W direction and the brittle deformation occurring at later stages producing fractures oriented in the E-W to NE-SW directions. These results have important implications in terms of regional tectonics and geological mapping as well as in land-use planning and other areas such as hydrogeology or geotechnics.

Endotoxin contamination and control in surface water sources and a drinking water treatment plant in Beijing, China.

PubMed

Can, Zhang; Wenjun, Liu; Wen, Sun; Minglu, Zhang; Lingjia, Qian; Cuiping, Li; Fang, Tian

2013-07-01

In this paper, endotoxin contamination was determined in treated water following each unit of a drinking water treatment plant (WTP) in Beijing, China and its source water (SW) from a long water diversion channel (Shijiazhuang-Beijing) originating from four reservoirs in Hebei province, China. The total-endotoxin activities in SW ranged from 21 to 41 EU/ml at five selected cross sections of the diversion channel. The total-endotoxin in raw water of the WTP ranged from 11 to 16 EU/ml due to dilution and pretreatment during water transportation from Tuancheng Lake to the WTP, and finished water of the WTP ranged from 4 to 10 EU/ml, showing a 49% decrease following the full-scale treatment process at the WTP. Compared with the 31% removal of free-endotoxin, the WTP removed up to 71% of bound-endotoxin in raw water. The traditional treatment processes (coagulation, sedimentation and filtration) in the WTP removed substantial amounts of total-endotoxin (up to 63%), while endotoxin activities increased after granular activated carbon (GAC) adsorption and chlorination. The total-endotoxin in the actual water was composed of free-endotoxin and bound-endotoxin (endotoxin aggregates, bacteria-bound endotoxins and particle-attached endotoxins). The endotoxin aggregates, bacteria-bound endotoxins and particle-attached endotoxins co-exist as suspended particles in water, and only the bacteria-bound endotoxins were correlated with bacterial cells suspended in water. The particle distribution of endotoxin aggregates in ultrapure water was also tested and the results showed that the majority (64-89%) of endotoxin aggregates had diameters <2 μm. The endotoxin contamination and control in treated water following each unit of the WTP processes and its SW from reservoirs are discussed and compared with regard to bacterial cell counts and particle characteristics, which were dependent, to a certain extent, on different flow rates and turbulence of the water environments. Copyright © 2013 Elsevier Ltd. All rights reserved.

The July 2016 Study of the water VApour in the polar AtmosPhere (SVAAP) campaign at Thule, Greenland: surface radiation budget and role of clouds

NASA Astrophysics Data System (ADS)

Meloni, Daniela; Di Iorio, Tatiana; di Sarra, Alcide; Iaccarino, Antonio; Pace, Giandomenico; Mevi, Gabriele; Muscari, Giovanni; Cacciani, Marco; Gröbner, Julian

2017-04-01

The Study of the water VApour in the polar AtmosPhere (SVAAP) project, funded by the Italian Programme for Antarctic Research, is aimed at investigating the surface radiation budget (SRB), the variability of atmospheric water vapour, and the long-term variations in stratospheric composition and structure at Thule, Greenland, in the framework of the international Network for Detection of Atmospheric Composition Change (NDACC). Thule High Arctic Atmospheric Observatory (THAAO, 76.5° N, 68.8° W) is devoted to study climate change and has been operational since 1990, with the contribution of different international institutions: DMI, NCAR, ENEA, INGV, Universities of Roma and Firenze (http://www.thuleatmos-it.it). As part of SVAAP an intensive field campaign was held at Thule from 5 to 28 July 2016. The campaign was also aimed at supporting the installation of VESPA-22, a new microwave radiometer for water vapour profiling in the upper atmosphere and integrated water vapour (IWV), and offered the possibility to study the cloud physical and optical properties and their impact on the SRB. Measurements of downward shortwave (SW) and longwave (LW) irradiance were already available since 2009. Additional observations were added to obtain the SRB and to characterize the atmospheric state: upward SW and LW irradiance, upwelling and downwelling photosynthetically active radiation (PAR), downward irradiance in the 8-14 µm infrared window, temperature and relative humidity tropospheric profiles, IWV, liquid water path (LWP), lidar tropospheric backscattering profiles, sky brightness temperature (BT) in the 9.6-11.5 µm spectral range, visible and infrared sky images, surface meteorological parameters. Moreover, 23 radiosonde were launched during the campaign. Data from the period 14-28 July are presented in this study. The first part of the campaign was characterized by stable cloud-free conditions, while alternation of cloudy and cloud-free sky occurred after 18 July. The time evolution of SW and LW SRB, surface albedo, and derived cloud parameters, such as cloud optical thickness and effective radius, are presented and discussed. Thickest clouds reached visible optical depths of about 200, and values of LWP of about 0.4 kg/m2. While the SW SRB is always positive during the measurement campaign, the LW SRB is negative under cloud-free conditions (own to -100 W/m2 at noon), becoming positive (up to +50 W/m2) during cloudy periods. The total (SW+LW) SRB is positive and its variability is dominated by the SW irradiance. Clouds induce a reduction of the SRB compared to the cloud-free periods, thanks to the dominant SW effect. The LW component offsets about 20% of the SW at noon in clear sky, and contributes up to 50% of the total SRB in thick cloud conditions. The availability of the cloud physical and optical properties and the atmospheric vertical profiles allow to study in details the SW and LW cloud radiative effect by means of radiative transfer simulations performed with MODTRAN6.0 model.

Direct Numerical Simulations of Dynamic Drainage and Imbibition to Investigate Capillary Pressure-Saturation-Interfacial Area Relation

NASA Astrophysics Data System (ADS)

Konangi, S.; Palakurthi, N. K.; Karadimitriou, N.; Comer, K.; Ghia, U.

2017-12-01

We present results of pore-scale direct numerical simulations (DNS) of drainage and imbibition in a quasi-two-dimensional (40µm thickness) porous medium with a randomly distributed packing of cylindrical obstructions. The Navier-Stokes (NS) equations are solved in the pore space on an Eulerian mesh using the open-source finite-volume computational fluid dynamics (CFD) code, OpenFOAM. The Volume-of-Fluid (VOF) method is employed to track the evolution of the fluid-fluid interface; a static contact angle is used to account for wall adhesion. From the DNS data, we focus on the macroscopic capillary pressure-saturation (Pc-Sw) relation, which is known to be hysteretic, i.e., this relation is flow process (such as drainage, imbibition and scanning curves) and history dependent. In order to overcome the problem of hysteresis, extended theories of multiphase flow hypothesized that the inclusion of specific interfacial area as a state variable will result in a unique relation between capillary pressure, saturation and interfacial area (Pc-Sw-awn). We study the role of specific interfacial area on hysteresis in the macroscopic Pc-Sw relation under non-equilibrium (dynamic) conditions. Under dynamic conditions, capillary pressure depends on the rate of change of the wetting phase saturation, and the dynamic Pc-Sw relation includes the changes caused by viscous effects. Simulations of drainage and imbibition are performed for two capillary numbers by controlling the flow rate of the non-wetting (polydimenthlysiloxane oil) and wetting (water) fluids. From these simulations, the Pc-Sw curves will be estimated; the Pc-S-awn surface will be constructed to determine whether the data points from drainage and imbibition processes fall on a unique surface under transient conditions. Different macroscopic capillary pressure definitions based on phase-averaged pressures and interfacial area will be evaluated. Understanding macroscopic capillary pressure definitions and the uniqueness of the Pc-S- awn relation is step towards complete description of two-phase flow at the Darcy scale.

Using coral Ba/Ca records to investigate seasonal to decadal scale biogeochemical cycling in the surface and intermediate ocean.

NASA Astrophysics Data System (ADS)

LaVigne, M.; Cobb, K. M.; DeLong, K. L.; Freiberger, M. M.; Grottoli, A. G.; Hill, T. M.; Miller, H. R.; Nurhati, I. S.; Richey, J. N.; Serrato Marks, G.; Sherrell, R. M.

2016-12-01

Dissolved barium (BaSW), a bio-intermediate element, is linked to several biogeochemical processes such as the cycling and export of nutrients, organic carbon (Corg), and barite in surface and intermediate oceans. Dynamic BaSW cycling has been demonstrated in the water column on short timescales (days-weeks) while sedimentary records have documented geologic-scale changes in barite preservation driven by export production. Our understanding of how seasonal-decadal scale climate variability impacts these biogeochemical processes currently lacks robust records. Ba/Ca calibrations in surface and deep sea corals suggest barium is incorporated via cationic substitution in both aragonite and calcite. Here we demonstrate the utility of Ba/Ca for reconstructing biogeochemical variability using examples of surface and deep sea coral records. Century-long deep sea coral records from the California Current System (bamboo corals: 900-1500m) record interannual variations in Ba/Ca, likely reflecting changes in barite formation via bacterial Corg respiration or barite saturation state. A surface Porites coral Ba/Ca record from Christmas Island (central equatorial Pacific: 1978-1995) shows maxima during low productivity El Niño warm periods, suggesting that variations in BaSW are driven by biological removal via direct cellular uptake or indirectly via barite precipitation with the decomposition of large phytoplankton blooms at this location. Similarly, a sixteen-year long Siderastera siderea surface coral record from Dry Tortugas, FL (Gulf of Mexico: 1991-2007) shows seasonal Ba/Ca cycles that align with annual chlorophyll and δ13C. Taken together, these records demonstrate the linkages among Corg, nutrient cycling and BaSW in the surface and intermediate ocean on seasonal to decadal timescales. Multi-proxy paleoceanographic reconstructions including Ba/Ca have the potential to elucidate the mechanisms linking past climate, productivity, nutrients, and BaSW cycling in the past.

Patient Responses on Quality of Care and Satisfaction with Staff After Integrated HIV Care in South African Primary Health Care Clinics.

PubMed

Rawat, Angeli; Uebel, Kerry; Moore, David; Cingl, Lubomir; Yassi, Annalee

2018-05-16

HIV care integrated into primary health care (PHC) encourages reorganized service delivery but could increase workload. In 2012-2013, we surveyed 910 patients and caregivers at two time points after integration in four clinics in Free State, South Africa. Likert surveys measured quality of care (QoC) and satisfaction with staff (SwS). QoC scores were lower for females, those older than 56 years, those visiting clinics every 3 months, and child health participants. Regression estimates showed QoC scores higher for ages 36-45 versus 18-25 years, and lower for those attending clinics for more than 10 years versus 6-12 months. Overall, SwS scores were lower for child health attendees and higher for tuberculosis attendees compared to chronic disease care attendees. Research is needed to understand determinants of disparities in QoC and SwS, especially for child health, diabetes, and hypertension attendees, to ensure high-quality care experiences for all patients attending PHC clinics with integrated HIV care. Copyright © 2018 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

Use of Student Experiments for Teaching Embedded Software Development Including HW/SW Co-Design

ERIC Educational Resources Information Center

Mitsui, H.; Kambe, H.; Koizumi, H.

2009-01-01

Embedded systems have been applied widely, not only to consumer products and industrial machines, but also to new applications such as ubiquitous or sensor networking. The increasing role of software (SW) in embedded system development has caused a great demand for embedded SW engineers, and university education for embedded SW engineering has…

Incremental Sampling Methodology (ISM) for Metallic Residues

DTIC Science & Technology

2013-08-01

Deviation (also %RSD) Sb Antimony Sn Tin Sr Strontium STD Standard Deviation ERDC TR-13-5 x SU Sampling Unit Ti Titanium UCL Upper Confidence Limit...Ce), chromium (Cr), Cu, Fe, Pb, mag- nesium (Mg), Mn, potassium (K), sodium (Na), strontium (Sr), titanium (Ti), W, zirconium (Zr), and Zn (Clausen...wastes. A proposed alternative to EPA SW 846 Method 3050. Environmental Science and Technology 23: 89 −900. Matzke, B., N. Hassig, J. Wilson, R. Gilber

Range extension of Pseudotorinia phorcysi (Gastropoda: Architectonicidae) from the SW Atlantic, with remarks on its ontogeny.

PubMed

Cavallari, Daniel C; Salvador, Rodrigo B

2016-10-17

Architectonicidae is a diverse family of heterobranch sea snails comprising over 11 genera and 140 extant species distributed worldwide (Bieler & Petit, 2005). They live in shallow to deep water, and have turbinate to discoidal shells, with a typically wide umbilicus and a downward-pointing (heterostrophic) protoconch (Healy, 1998). Pseudotorinia phorcysi Cavallari, Salvador & Simone, 2013 is a deep-water species known only from its type locality in the SW Atlantic, off Cabo Frio, Rio de Janeiro state, Brazil (23°41'S 42°06'W, 430-450 m depth). Its original description was based on a single eroded juvenile specimen collected by the French-Brazilian expedition "Marion Dufresne" MD55 in the late 1980s (Cavallari et al., 2014).

In vitro and in vivo sensitization of SW620 metastatic colon cancer cells to CDDP-induced apoptosis by the nitric oxide donor DETANONOate: Involvement of AIF.

PubMed

Huerta, Sergio; Baay-Guzman, Guillermina; Gonzalez-Bonilla, Cesar R; Livingston, Edward H; Huerta-Yepez, Sara; Bonavida, Benjamin

2009-05-01

Tumor cells develop mechanisms that dysregulate apoptotic pathways resulting in resistance to cytotoxic stimuli. Primary SW480 and metastatic SW620 colon cancer cells are resistant to CDDP-induced apoptosis. Apoptosis-inducing factor (AIF) was significantly downregulated in SW620 compared to SW480 cells; while apoptotic mediators such as Bax, Bcl-2, and Bcl(XL) were not altered in these cell lines. Examination of tumor tissues from patients with colon cancer demonstrated a significant downregulation of AIF in patients with advanced disease. The role of AIF expression in resistance was examined. Several lines of evidence suggest the involvement of AIF expression level in the sensitivity of SW620 to CDDP-induced apoptosis: (1) sensitization of SW620 by the NO donor DETANONOate to CDDP-induced apoptosis correlated with the induction of AIF as assessed by RT-PCR and Western blot analysis, (2) treatment of SW620 cells with siRNA AIF, but not with control siRNAs, inhibited DETANONOate-induced sensitization to CDDP apoptosis, (3) sensitization by DETANONOate observed in vitro was corroborated in vivo in nude mice bearing SW620 tumor xenografts and treated with the combination of DETANONOate and CDDP, and (4) tumor tissues derived from the SW620 xenografts revealed significant upregulation of AIF and increased apoptosis by DETANONOate and CDDP combination treatment. Altogether, these findings underscore the potential therapeutic application of NO donors and subtoxic chemotherapeutic drugs in the treatment of advanced colon cancer resistant to conventional chemotherapeutic agents.

Shock Wave Therapy Enhances Angiogenesis through VEGFR2 Activation and Recycling

PubMed Central

Huang, Tien-Hung; Sun, Cheuk-Kwan; Chen, Yi-Ling; Wang, Ching-Jen; Yin, Tsung-Cheng; Lee, Mel S; Yip, Hon-Kan

2016-01-01

Although low-energy shock wave (SW) is adopted to treat ischemic diseases because of its pro-angiogenic properties, the underlying mechanism remains unclear. This study is aimed at testing whether SW-induced angiogenesis may be through endothelial vascular endothelial growth factor receptor 2 (VEGFR2) signaling and trafficking. Phosphorylation of VEGFR2- Akt-eNOS axis and production of nitric oxide (NO) were determined in human umbilical vein endothelial cells (HUVECs) treated with SW. Carotid artery in ob/ob mice was treated with SW before evaluation with sprouting assay. Critical limb ischemia was induced in ob/ob mice to evaluate blood flow recovery post-SW treatment. Tube formation and migration assays were also performed with/without SW treatment in the presence/absence of SU5416 (VEGFR2 kinase inhibitor) and siRNA-driven silencing of VEGFR2. Chloroquine was used for disrupting endosome, and Rab11a controlling slow endocytic recycling was silenced with siRNA in vitro. Following SW treatment, augmented ligand-independent phosphorylation in VEGFR2-Akt-eNOS axis and endogenous NO production, increased cellular migration and tube formation and elevated sprouting of carotid artery and blood flow in ischemic limb in ob/ob mice were noted. Moreover, SU5416 and VEGFR2 silencing both inhibited SW-induced angiogenesis. SW-induced angiogenesis, accompanied by increased VEGFR2 protein expression without transcriptional change, was suppressed by chloroquine and Rab11a silencing. We concluded that SW enhanced angiogenesis via ligand-independent activation of VEGFR2 and further prolonged angiogenesis through endosome-to-plasma membrane recycling in endothelial cells. PMID:27925633

Overexpression of secretagogin promotes cell apoptosis and inhibits migration and invasion of human SW480 human colorectal cancer cells.

PubMed

Yang, Xiang-Yi; Liu, Qiao-Rui; Wu, Li-Ming; Zheng, Xu-Lei; Ma, Cong; Na, Ri-Su

2018-05-01

In order to investigate the effect of secretagogin (SCGN) on colorectal cancer (CRC) cells apoptosis, invasion and migration in vitro. Expression of SCGN in CRC tissues and the paired adjacent non-tumorous tissues (n = 36) and four human CRC cell lines (HT29, HCT116, SW480 and SW620) were detected. SW480 cells were transfected with the SCGN overexpression plasmid (eGFP-SCGN), si-SCGN-773, and the corresponding negative controls (NCs). Then, cell-cycle distribution, cell apoptosis, migration, invasion and expression of apoptosis- and metastasis-related proteins were detected. SCGN was significantly downregulated in CRC tissues as compared with the adjacent non-tumorous tissues. The expression of SCGN in HT29 and SW480 cells were lower than those in HT116 and SW620 cells. We transfected SW480 cells with SCGN overexpression plasmid eGFP-SCGN and found the increased cell apoptosis, with cell arresting at G0/G1 phase. SW480 cells with SCGN overexpression showed wider wound width and fewer invaded cells than control and blank cells, with upregulated Bax, cleaved Caspase 3 and E-cadherin, and downregulated Bcl-2 and Vimentin. We also transfected SW480 cells with si-SCGN-773 and found si-SCGN increased cell migration and invasion, but did not affect cell apoptosis and expression of related proteins. We concluded that the overexpression of SCGN in SW480 cells promoted cell apoptosis and inhibited cell migration and invasion. Copyright © 2018. Published by Elsevier Masson SAS.

[Effect of smoke water and distillation liquid on the seed germination and seedling growth of Trichosathes kirilowii].

PubMed

Zhou, Jie; Bian, Li-hua; Zou, Lin; Zhou, Bin-qian; Liu, Wei; Wang, Xiao

2015-10-01

Smoke water and distillation liquid were used to treat the seeds of Trichosathes kirilowii and to study the effects of smoke water and distillation liquid on the seed germination and seedling growth of T. kirilowii. The results showed that germination rate, germination index and germination vigor of T. kirilowii all were significantly improved with the treatment of SW and DL treatment. The activity of α-amylase were significantly increased with the treatment of SW and DL at 1:2,000. SW and DL treatment showed no significant effects on the activity of SOD. The activity of POD were markedly enhanced under the treatment of SW (1:000) and DL (1:2,000). CAT activity were increased with the treatment of SW and DL at 1:2,000 while were inhibited by SW and DL at 1:500. Seedling height and root length were increased with the treatment of SW and DL (1:1,000, 1:2,000). SW and DL treaments improved the content of chlorophyll, and moreover with the concentration of SW and DL, the stimulatory were also increased. This work demonstrated that smoke water and diatillation liquid at 1:2,000 could stimulate the seed germination and seedling growth of T. kirilowii, and it provided the references for the study of seed germination technology.

Extracorporeal low-energy shock-wave therapy exerts anti-inflammatory effects in a rat model of acute myocardial infarction.

PubMed

Abe, Yuzuru; Ito, Kenta; Hao, Kiyotaka; Shindo, Tomohiko; Ogata, Tsuyoshi; Kagaya, Yuta; Kurosawa, Ryo; Nishimiya, Kensuke; Satoh, Kimio; Miyata, Satoshi; Kawakami, Kazuyoshi; Shimokawa, Hiroaki

2014-01-01

It has been previously demonstrated that extracorporeal low-energy shock-wave (SW) therapy ameliorates left ventricular (LV) remodeling through enhanced angiogenesis after acute myocardial infarction (AMI) in pigs in vivo. However, it remains to be examined whether SW therapy also exerts anti-inflammatory effects on AMI. METHODS AND RESULTS: AMI was created by ligating the proximal left anterior descending coronary artery in rats. They were randomly assigned to 2 groups: with (SW group) or without (control group) SW therapy (0.1 mJ/mm(2), 200 shots, 1 Hz to the whole heart at 1, 3 and 5 days after AMI). Four weeks after AMI, SW therapy significantly ameliorated LV remodeling and fibrosis. Histological examinations showed that SW therapy significantly suppressed the infiltration of neutrophils and macrophages at days 3 and 6, in addition to enhanced capillary density in the border area. Molecular examinations demonstrated that SW therapy enhanced the expression of endothelial nitric oxide synthase and suppressed the infiltration of transforming growth factor-β1-positive cells early after AMI. SW therapy also upregulated anti-inflammatory cytokines and downregulated pro-inflammatory cytokines in general. These results suggest that low-energy SW therapy suppressed post-MI LV remodeling in rats in vivo, which was associated with anti-inflammatory effects in addition to its angiogenic effects, and demonstrated a novel aspect of the therapy for AMI.

Federal climate change programs in the water-limited Southwest: intersection of mission, stakeholders and geography to build successful collaboration

NASA Astrophysics Data System (ADS)

Elias, E.; Steele, C. M.; Rango, A.; Reyes, J. J.; Langston, M. A.; Johnson, K.

2016-12-01

As one of the newest federal programs to emerge in response to climate change, the U.S. Department of Agriculture (USDA) Climate Hubs were established to assist farmers, ranchers and forest landowners in their adaptation and mitigation efforts under a changing climate. The Hubs' mission is to deliver science-based information and tools to agricultural and natural resource land managers, to enable climate-informed decision-making. By facilitating and transferring tools and knowledge, the Hubs also provide value to cooperative extension, land grant institutions, and USDA itself, especially in leveraging existing resource capacity. Various federal agencies (NOAA, USGS, USFWS) have also developed climate change coordination networks: RISAs, CSCs, and LCCs. These regionally-based federal networks can best operate in collaboration with one another. At their programmatic level, however, there are fundamental discrepancies in mission, stakeholder definition and geographic region. In this presentation, we seek to compare and contrast these divergent characteristics by identifying `hot spots' and `hot moments' where definitions, programs, or priorities may intersect due to place-based or event-based issues. The Southwest (SW) region of the United States, which presently operates under warm and dry conditions, is projected to become warmer and drier in the future. On-going drought conditions have presented an opportunity to maintain and build professional networks among these federal climate change coordination networks, as well as within USDA, to better understand impacts and respond to stakeholder needs. Projects in the Rio Grande River Valley and with Tribal nations highlight successful collaboration based on geography and common stakeholders, respectively. Aridity and water scarcity characterize the SW region and provide an overarching theme to better support adaptation and mitigation, as well as create opportunities for collaborative success.

Geophysical characterisation of the groundwater-surface water interface

NASA Astrophysics Data System (ADS)

McLachlan, P. J.; Chambers, J. E.; Uhlemann, S. S.; Binley, A.

2017-11-01

Interactions between groundwater (GW) and surface water (SW) have important implications for water quantity, water quality, and ecological health. The subsurface region proximal to SW bodies, the GW-SW interface, is crucial as it actively regulates the transfer of nutrients, contaminants, and water between GW systems and SW environments. However, geological, hydrological, and biogeochemical heterogeneity in the GW-SW interface makes it difficult to characterise with direct observations. Over the past two decades geophysics has been increasingly used to characterise spatial and temporal variability throughout the GW-SW interface. Geophysics is a powerful tool in evaluating structural heterogeneity, revealing zones of GW discharge, and monitoring hydrological processes. Geophysics should be used alongside traditional hydrological and biogeochemical methods to provide additional information about the subsurface. Further integration of commonly used geophysical techniques, and adoption of emerging techniques, has the potential to improve understanding of the properties and processes of the GW-SW interface, and ultimately the implications for water quality and environmental health.

The Robust Software Feedback Model: An Effective Waterfall Model Tailoring for Space SW

NASA Astrophysics Data System (ADS)

Tipaldi, Massimo; Gotz, Christoph; Ferraguto, Massimo; Troiano, Luigi; Bruenjes, Bernhard

2013-08-01

The selection of the most suitable software life cycle process is of paramount importance in any space SW project. Despite being the preferred choice, the waterfall model is often exposed to some criticism. As matter of fact, its main assumption of moving to a phase only when the preceding one is completed and perfected (and under the demanding SW schedule constraints) is not easily attainable. In this paper, a tailoring of the software waterfall model (named “Robust Software Feedback Model”) is presented. The proposed methodology sorts out these issues by combining a SW waterfall model with a SW prototyping approach. The former is aligned with the SW main production line and is based on the full ECSS-E-ST-40C life-cycle reviews, whereas the latter is carried out in advance versus the main SW streamline (so as to inject its lessons learnt into the main streamline) and is based on a lightweight approach.

Study of morphological and mechanical features of multinuclear and mononuclear SW480 cells by atomic force microscopy.

PubMed

Liu, Jinyun; Qu, Yingmin; Wang, Guoliang; Wang, Xinyue; Zhang, Wenxiao; Li, Jingmei; Wang, Zuobin; Li, Dayou; Jiang, Jinlan

2018-01-01

This article studies the morphological and mechanical features of multinuclear and mononuclear SW480 colon cancer cells by atomic force microscopy to understand their drug-resistance. The SW480 cells were incubated with the fullerenol concentrations of 1 mg/ml and 2 mg/ml. Morphological and mechanical features including the height, length, width, roughness, adhesion force and Young's modulus of three multinuclear cell groups and three mononuclear cell groups were imaged and analyzed. It was observed that the features of multinuclear cancer cells and mononuclear cancer cells were significantly different after the treatment with fullerenol. The experiment results indicated that the mononuclear SW480 cells were more sensitive to fullerenol than the multinuclear SW480 cells, and the multinuclear SW480 cells exhibited a stronger drug-resistance than the mononuclear SW480 cells. This work provides a guideline for the treatments of multinuclear and mononuclear cancer cells with drugs. © 2017 Wiley Periodicals, Inc.

Novel mechanism of gene transfection by low-energy shock wave.

PubMed

Ha, Chang Hoon; Lee, Seok Cheol; Kim, Sunghyen; Chung, Jihwa; Bae, Hasuk; Kwon, Kihwan

2015-08-05

Extracorporeal shock wave (SW) therapy has been studied in the transfection of naked nucleic acids into various cell lines through the process of sonoporation, a process that affects the permeation of cell membranes, which can be an effect of cavitation. In this study, siRNAs were efficiently transfected into primary cultured cells and mouse tumor tissue via SW treatment. Furthermore SW-induced siRNA transfection was not mediated by SW-induced sonoporation, but by microparticles (MPs) secreted from the cells. Interestingly, the transfection effect of the siRNAs was transferable through the secreted MPs from human umbilical vein endothelial cell (HUVEC) culture medium after treatment with SW, into HUVECs in another culture plate without SW treatment. In this study, we suggest for the first time a mechanism of gene transfection induced by low-energy SW through secreted MPs, and show that it is an efficient physical gene transfection method in vitro and represents a safe therapeutic strategy for site-specific gene delivery in vivo.

Vernal Crater, SW Arabia Terra: MSL Candidate with Extensively Layered Sediments, Possible Lake Deposits, and a Long History of Subsurface Ice

NASA Technical Reports Server (NTRS)

Oehler, Dorothy Z.; Allen, Carlton C.

2007-01-01

Vernal Crater is a Mars Science Laboratory (MSL) landing site candidate providing relatively easy access to extensively layered sediments as well as potential lake deposits. Sediments of Vernal Crater are 400-1200 m below those being investigated by Opportunity in Meridiani Planum, and as such would allow study of significantly older geologic units, if Vernal Crater were selected for MSL. The location of Vernal Crater in SW Arabia Terra provides exceptional scientific interest, as rampart craters and gamma-ray spectrometer (GRS) data from the region suggest a long history of ice/fluids in the subsurface. The potential value of this MSL candidate is further enhanced by reports of atmospheric methane over Arabia, as any insight into the source of that methane would significantly increase our understanding of Mars. Finally, should MSL survive beyond its prime mission, the gentle slope within Vernal Crater would provide a route out of the crater for study of the once ice/fluid-rich plains.

Tectonic controls on the genesis of ignimbrites from the Campanian Volcanic Zone, southern Italy

USGS Publications Warehouse

Rolandi, G.; Bellucci, F.; Heizler, M.T.; Belkin, H.E.; de Vivo, B.

2003-01-01

The Campanian Plain is an 80 x 30 km region of southern Italy, bordered by the Apennine Chain, that has experienced subsidence during the Quaternary. This region, volcanologically active in the last 600 ka, has been identified as the Campanian Volcanic Zone (CVZ). The products of three periods of trachytic ignimbrite volcanism (289-246 ka, 157 ka and 106 ka) have been identified in the Apennine area in the last 300 ka. These deposits probably represent distal ash flow units of ignimbrite eruptions which occurred throughout the CVZ. The resulting deposits are interstratified with marine sediments indicating that periods of repeated volcano-tectonic emergence and subsidence may have occurred in the past. The eruption, defined as the Campanian Ignimbrite (CI), with the largest volume (310 km3), occurred in the CVZ 39 ka ago. The products of the CI eruption consist of two units (unit-1 and unit-2) formed from a single compositionally zoned magma body. Slightly different in composition, three trachytic melts constitute the two units. Unit-1 type A is an acid trachyte, type B is a trachyte and type C of unit-2 is a mafic trachyte. The CI, vented from pre-existing neotectonic faults, formed during the Apennine uplift, Initially the venting of volatile-rich type A magma deposited the products to the N-NE of the CVZ. During the eruption, the Acerra graben already affected by a NE-SW fault system, was transected by E-W faults, forming a cross-graben that extended to the gulf of Naples. E-W faults were then further dislocated by NE-SW transcurrent movements. This additional collapse significantly influenced the deposition of the B-type magma of unit-1, and the C-type magma of unit-2 toward the E-SE and S, in the Bay of Naples. The pumice fall deposit underlying the CI deposits, until now thought to be associated with the CI eruption, is not a strict transition from plinian to CI-forming activity. It is derived instead from an independent source probably located near the Naples area. This initial volcanic activity is assumed to be a precursor to the CI trachytic eruptions, which vented along regional faults.

Corrective Action Investigation Plan for Corrective Action Unit 405: Area 3 Septic Systems, Tonopah Test Range, Nevada(April 2001, Rev. 0) with Record of Technical Change No. 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

DOE /NV

2001-04-26

This Corrective Action Investigation Plan contains the U.S. Department of Energy, Nevada Operations Office's (DOE/NV's) approach to collect the data necessary to evaluate corrective action alternatives appropriate for the closure of Corrective Action Unit (CAU) 405, Area 3 Septic Systems, Tonopah Test Range (TTR), under the Federal Facility Agreement and Consent Order. Corrective Action Unit 405 consists of Corrective Action Sites 03-05-002-SW03, 03-05-002-SW04, and 03-05-002-SW07 (also collectively known as: Septic Waste Systems [SWSs] 3, 4, and 7). Located in Area 3 in the northwest section of the TTR, approximately 140 miles northwest of Las Vegas, this location was historically (betweenmore » 1960 and 1990) used as a research facility with the mission to perform defense-related projects, and whose operations generated sanitary and industrial wastewaters potentially contaminated with COPCs and disposed of in septic tanks and leachfields. Though Septic Waste Systems 3, 4, and 7 were origin ally constructed to receive sanitary sewage, they may have inadvertently received effluent containing potentially hazardous and radiological constituents containing acetone, benzene, ethylbenzene, 4-methyl-2-pentanone, toluene, xylenes, volatile organic compound constituents, phenols, arsenic, barium, lead, mercury, hydrocarbons of oil and grease, and uranium-234, -235, and -238. The Area 3 septic systems were documented in a DOE/NV 1996 report as being included in the septic tank abandonment program conducted by Sandia National Laboratories in 1993; however, this program was not completed and the possibility exists that some of the Area 3 septic tanks may not have been abandoned. Even though all of the SWSs addressed in this CAIP are inactive, geophysical surveys conducted in 1993 were generally inconclusive and did not provide useful data for the purposes of this investigation. The scope of this current investigation, therefore, will be to determine the existence of the identified CO PCs and excavation will be the primary investigation method employed for these leachfield systems, but this effort may be limited by existing facilities and utilities. The results of this field investigation will support a defensible evaluation of corrective action alternatives in the subsequent corrective action decision document.« less

5. DETAIL VIEW OF THE EGYPTIAN MOTIF DECORATIVE ELEMENTS OF ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. DETAIL VIEW OF THE EGYPTIAN MOTIF DECORATIVE ELEMENTS OF BUILDING 1'S MAIN ENTRY TOWER (INCLUDING THE ENGAGED COLUMN CAPITALS, PILASTERS & CAPITALS, CORNICES, AND TERRA COTTA EAGLES); LOOKING SW FROM THE E WING ROOF. (Ryan) - Veterans Administration Medical Center, Building No. 1, Old State Route 13 West, Marion, Williamson County, IL

Assessing Crop Vulnerability to Climate Change: A Southwest Perspective

USDA-ARS?s Scientific Manuscript database

The USDA Southwest Regional Climate Hub is one of ten Climate Hubs and Sub-hubs established in 2014. The Hub region includes Arizona, California (partnering with the California Sub-Hub), Nevada, New Mexico and Utah.  Beyond the mainland States, the SW hub also serves Hawaii and the US affiliated Pac...

40 CFR 278.3 - Criteria for use of chat in Federally funded transportation projects.

Code of Federal Regulations, 2010 CFR

2010-07-01

... funded transportation projects. 278.3 Section 278.3 Protection of Environment ENVIRONMENTAL PROTECTION... Leaching Procedure (SPLP) tests are conducted on the proposed material using EPA SW-846 Method 1312...) EPA (or a State environmental Agency, if it chooses to do so) has determined, based on a site-specific...

15. Photograph of an historic photograph in the possession of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Photograph of an historic photograph in the possession of the Engineer's Office of the Marion, IL Veterans Administration Medical Center. HOSPITAL BUILDING #1; E & N (FRONT) ELEVATIONS, LOOKING SW; DATED MAY 18, 1942. - Veterans Administration Medical Center, Building No. 1, Old State Route 13 West, Marion, Williamson County, IL

Acquisition of Involuntary Spinal Locomotion (Spinal Walking) in Dogs with Irreversible Thoracolumbar Spinal Cord Lesion: 81 Dogs.

PubMed

Gallucci, A; Dragone, L; Menchetti, M; Gagliardo, T; Pietra, M; Cardinali, M; Gandini, G

2017-03-01

Spinal walking (SW) is described as the acquisition of an involuntary motor function in paraplegic dogs and cats without pain perception affected by a thoracolumbar lesion. Whereas spinal locomotion is well described in cats that underwent training trials after experimental spinal cord resection, less consistent information is available for dogs. Paraplegic dogs affected by a thoracolumbar complete spinal cord lesion undergoing intensive physical rehabilitation could acquire an autonomous SW gait under field conditions. Eighty-one acute paraplegic thoracolumbar dogs without pelvic limb pain perception. Retrospective study of medical records of dogs selected for intensive rehabilitation treatment in paraplegic dogs with absence of pain perception on admission and during the whole treatment. Binary regression and multivariate logistic regression were used to analyze potential associations with the development of SW. Autonomous SW was achieved in 48 dogs (59%). Median time to achieve SW was of 75.5 days (range: 16-350 days). On univariate analysis, SW gait was associated with younger age (P = .002) and early start of physiotherapy (P = .024). Multivariate logistic regression showed that younger age (≤60 months) and lightweight (≤7.8 kg) were positively associated with development of SW (P = .012 and P < .001, respectively). BCS, full-time hospitalization, and type and site of the lesion were not significantly associated with development of SW. Dogs with irreversible thoracolumbar lesion undergoing intensive physiotherapic treatment can acquire SW. Younger age and lightweight are positively associated with the development of SW gait. Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

Simulating planetary wave propagation to the upper atmosphere during stratospheric warming events at different mountain wave scenarios

NASA Astrophysics Data System (ADS)

Gavrilov, Nikolai M.; Koval, Andrey V.; Pogoreltsev, Alexander I.; Savenkova, Elena N.

2018-04-01

Parameterization schemes of atmospheric normal modes (NMs) and orographic gravity waves (OGWs) have been implemented into the mechanistic Middle and Upper Atmosphere Model (MUAM) simulating atmospheric general circulation. Based on the 12-members ensemble of runs with the MUAM, a composite of the stratospheric warming (SW) has been constructed using the UK Met Office data as the lower boundary conditions. The simulation results show that OGW amplitudes increase at altitudes above 30 km in the Northern Hemisphere after the SW event. At altitudes of about 50 km, OGWs have largest amplitudes over North American and European mountain systems before and during the composite SW, and over Himalayas after the SW. Simulations demonstrate substantial (up to 50-70%) variations of amplitudes of stationary planetary waves (PWs) during and after the SW in the mesosphere-lower thermosphere of the Northern Hemisphere. Westward travelling NMs have amplitude maxima not only in the Northern, but also in the Southern Hemisphere, where these modes have waveguides in the middle and upper atmosphere. Simulated variations of PW and NM amplitudes correspond to changes in the mean zonal wind, EP-fluxes and wave refractive index at different phases of the composite SW events. Inclusion of the parameterization of OGW effects leads to decreases in amplitudes (up to 15%) of almost all SPWs before and after the SW event and their increase (up to 40-60%) after the SW in the stratosphere and mesosphere at middle and high northern latitudes. It is suggested that observed changes in NM amplitudes in the Southern Hemisphere during SW could be caused by divergence of increased southward EP-flux. This EP-flux increases due to OGW drag before SW and extends into the Southern Hemisphere.

Brief report: treating stuttering in an adult with autism spectrum disorder.

PubMed

Brundage, Shelley B; Whelan, Cory J; Burgess, Cathleen M

2013-02-01

Stuttering and autism can co-occur and when they do it presents a significant communication challenge. This study examined the effectiveness of a modified version of the fluency rules program (FRP; Runyan and Runyan, Stuttering and related disorders of fluency, in 2007) to reduce stuttering frequency in a man with autism spectrum disorder (ASD). The participant's percentage of stuttered words (%SW) was calculated during conversational interactions with multiple conversation partners both within and outside of the clinic treatment sessions. Visual inspection methods revealed a reduction in %SW from an average of 14.5 %SW during baseline to 2.07 %SW during the withdrawal phase. The mean baseline reduction in %SW from baseline to the second treatment phase was 91.8 %. The FRP holds promise for reducing %SW in persons with ASD who stutter.

Test Analysis Tools to Ensure Higher Quality of On-Board Real Time Software for Space Applications

NASA Astrophysics Data System (ADS)

Boudillet, O.; Mescam, J.-C.; Dalemagne, D.

2008-08-01

EADS Astrium Space Transportation, in its Les Mureaux premises, is responsible for the French M51 nuclear deterrent missile onboard SW. There was also developed over 1 million of line of code, mostly in ADA, for the Automated Transfer Vehicle (ATV) onboard SW and the flight control SW of the ARIANE5 launcher which has put it into orbit. As part of the ATV SW, ASTRIUM ST has developed the first Category A SW ever qualified for a European space application. To ensure that all these embedded SW have been developed with the highest quality and reliability level, specific development tools have been designed to cover the steps of source code verification, automated validation test or complete target instruction coverage verification. Three of such dedicated tools are presented here.

Physical properties of lava flows on the southwest flank of Tyrrhena Patera, Mars

NASA Technical Reports Server (NTRS)

Crown, David A.; Porter, Tracy K.; Greeley, Ronald

1991-01-01

Tyrrhena Patera (TP) (22 degrees S, 253.5 degrees W), a large, low-relief volcano located in the ancient southern highlands of Mars, is one of four highland paterae thought to be structurally associated with the Hellas basin. The highland paterae are Hesperian in age and among the oldest central vent volcanoes on Mars. The morphology and distribution of units in the eroded shield of TP are consistent with the emplacement of pyroclastic flows. A large flank unit extending from TP to the SW contains well-defined lava flow lobes and leveed channels. This flank unit is the first definitive evidence of effusive volcanic activity associated with the highland paterae and may include the best preserved lava flows observed in the Southern Hemisphere of Mars. Flank flow unit averages, channelized flow, flow thickness, and yield strength estimates are discussed. Analysis suggests the temporal evolution of Martian magmas.

The Relationship Between Non-Medical Use of Prescription Opioids and Sex Work Among Adults in Residential Substance Use Treatment.

PubMed

Matusiewicz, Alexis K; Ilgen, Mark A; Bonar, Erin E; Price, Amanda; Bohnert, Amy S B

2016-05-01

High rates of substance use (e.g., alcohol, cocaine, heroin) have been documented among individuals who engage in sex work (SW), and adults seeking substance use disorder (SUD) treatment frequently report prior engagement in SW. Non-medical use of prescription opioids (NMUPO) has increased over the last decade, but little is known about the relationship between NMUPO with sex exchange. The purpose of this study was to describe the prevalence of recent SW among patients at a large residential SUD treatment center and examine the association between NMUPO and SW. Approximately 14% of 588 adults reported involvement in SW in the month prior to treatment. NMUPO was more common among those with a history of SW (95% of sex workers vs. 74% of non-sex-workers), and this association remained statistically significant after controlling for demographic factors, other substance use and psychiatric symptom severity (odds ratio=3.38). SW is relatively common among patients in residential SUD treatment, and is associated with greater psychiatric severity and more extensive substance use, including alarming rates of NMUPO. Addiction treatment for individuals involved in SW may benefit from the addition of content related to NMUPO. Copyright © 2016. Published by Elsevier Inc.

Shock wave induced sonoporation and gene transfer

NASA Astrophysics Data System (ADS)

Miller, Douglas L.

2003-10-01

During shockwave (SW) treatment, cavitation activity can be applied for cell killing. A bonus is that some surviving cells appear to be briefly permeabilized, or sonoporated, allowing them to take up large molecules including DNA. In vitro research has indicated that as the number of SW increased, survival declined exponentially but the number of sonoporated cells increased to better than 50% of survivors for 1000 SW. In vivo tests have demonstrated SW-induced tumor ablation could indeed be accompanied by the transfection of marker plasmids into mouse B16 melanoma tumors in vivo. With intratumor injection of plasmid DNA and air bubbles, significant results were obtained for only 400 SW. In a trial of cancer therapy, the effects of 500 SW combined with interleukin-12 immuno-gene therapy was observed on the progression of two mouse tumors, B16 melanoma and RENCA renal carcinoma. The combination of SW and IL-12 plasmid injection provided a statistically significant inhibition of tumor growth relative to SW alone for both tumor models, demonstrating feasibility for this treatment method. In the future, the development of intravenous gene delivery and improved transfection, together with image-guided ultrasound treatment, should lead to the clinical application of ultrasound enhanced gene therapy. [Work supported by NIH Grant No. EB002782.

SW radiative effect of aerosol in GRAPES_GFS

NASA Astrophysics Data System (ADS)

Chen, Qiying

2017-04-01

The aerosol particles can scatter and absorb solar radiation, and so change the shortwave radiation absorbed by the atmosphere, reached the surface and that reflected back to outer space at TOA. Since this process doesn't interact with other processes, it is called direct radiation effect. The clear sky downward SW and net SW fluxes at the surface in GRAPES_GFS of China Meteorological Administration are overestimated in Northern multitudes and Tropics. The main source of these errors is the absence of aerosol SW effect in GRAPES_GFS. The climatic aerosol mass concentration data, which include 13 kinds of aerosol and their 14 SW bands optical properties are considered in GRAPES_GFS. The calculated total optical depth, single scatter albedo and asymmetry factor are used as the input to radiation scheme. Compared with the satellite observation from MISER, the calculated total optical depth is in good consistent. The seasonal experiments show that, the summer averaged clear sky radiation fluxes at the surface are improved after including the SW effect of aerosol. The biases in the clear sky downward SW and net SW fluxes at the surface in Northern multitudes and Tropic reduced obviously. Furthermore, the weather forecast experiments also show that the skill scores in Northern hemisphere and East Asia also become better.

Evaluation of DNA Repair Function as a Predictor of Response in a Clinical Trial of PARP Inhibitor Monotherapy for Recurrent Ovarian Carcinoma

DTIC Science & Technology

2015-10-01

Monotherapy for Recurrent Ovarian Carcinoma PRINCIPAL INVESTIGATOR: Scott H. Kaufmann CONTRACTING ORGANIZATION: Mayo Clinic Rochester, MN 55905...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Mayo Clinic and Foundation AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT...NUMBER 200 First St., S.W. Rochester, MN 55905 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) Mayo Clinic Rochester, MN 55905 10. SPONSOR

Duplex thrusting in the South Dabashan arcuate belt, central China

NASA Astrophysics Data System (ADS)

Li, Wangpeng; Liu, Shaofeng; Wang, Yi; Qian, Tao; Gao, Tangjun

2017-10-01

Due to later tectonic superpositioning and reworking, the South Dabashan arcuate belt extending NW to SE has experienced several episodes of deformation. The earlier deformational style and formation mechanism of this belt remain controversial. Seismic interpretations and fieldwork show that the curved orogen can be divided into three sub-belts perpendicular to the strike of the orogen, the imbricate thrust fault belt, the detachment fold belt and the frontal belt from NE to SW. The imbricate thrust fault belt is characterized by a series of SW-directed thrust faults and nappes. Two regional detachment layers at different depths have been recognized in the detachment fold and frontal belts, and these detachment layers divide the sub-belts into three structural layers: the lower, middle, and upper structural layers. The middle structural layer is characterized by a passive roof duplex structure, which is composed of a roof thrust at the top of the Sinian units, a floor thrust in the upper Lower Triassic units, and horses in between. Apatite fission track dating results and regional structural analyses indicate that the imbricate thrust fault belt may have formed during the latest Early Cretaceous to earliest Paleogene and that the detachment fold belt may have formed during the latest Late Cretaceous to earliest Neogene. Our findings provide important reference values for researching intra-continental orogenic and deformation mechanisms in foreland fold-thrust belts.

Landsat TM data processing for lithological discrimination in the Caraculo area (Namibe Province, SW Angola)

NASA Astrophysics Data System (ADS)

Alberti, A.; Alessandro, V.; Pieruccini, U.; Pranzini, E.

1993-10-01

Landsat TM data were used for lithological discrimination and mapping in the little-known, semiarid 900 km 2 area around Caraculo station and the middle course of the Rio Giraul (Namibe Province, SW Angola) following two main procedures. The first of these was based on visual evaluation of three-band composites, band-ratio composites and Principal Component Analysis. The second method relied on the extraction of spectral signatures, and their use to obtain automatic classifications. Satisfactory results were reached with the first procedure, thus allowing - with limited support of ground information — the draft of a lithological map, while the second method was not systematically efficient, even for confirmation of data acquired with the first procedure. Image interpretation suggests that an extensive but hithertoun differentiated metasedimentary complex consisting of a heterogeneous supracrustal sequence should be subdivided into at least two units. Field observations proved that one of these is marked by a notable frequency of marbles and the other is characterized by a widespread occurrence of amphibolitic bodies. Moreover, a belt of undetermined (thermally metamorphosed ?) metamorphic rocks is interposed between them. The distinction of so far unidentified units, though restricted to interpretation of processed Landsat TM data, has significant geological implications also in the regional context and will be helpful in guiding future work with conventional geological methods.

Strain development and kinematic significance of the Alpine folding on Andros (western Cyclades, Greece)

NASA Astrophysics Data System (ADS)

Ziv, A.; Katzir, Y.; Avigad, D.; Garfunkel, Z.

2010-06-01

The general trend of both fold axes and stretching lineation in the Cycladic Blueschist Unit is NE-SW to NNE-SSW. This orientation forms a large angle (almost perpendicular) with respect to the Hellenic trend that is inferred from the main thrusts on mainland Greece. Thus, the kinematic significance of the stretching parallel folding in the Cycladic Blueschist Unit is non-trivial. Since within the western Cyclades, the NE-trending folds are best exposed on the island of Andros, it is a key locality for understanding the timing, style and kinematic significance of folding. Here we show that the NE-trending folds on Andros formed within the stability field of glaucophane, after the peak high-pressure metamorphism and simultaneously with the early stage of retrogression. The axes-parallel stretching was non-rotational; it started during the NE folding at blueschist-facies conditions, and continued long afterward and well into the retrograde greenschist overprint. Furthermore, we present the result of a finite strain calculation which shows that the large NE folds could not have been reoriented at ~ 90° as previously thought. Instead it is suggested that these folds formed under constrictional strain regime during regional NE-SW extension, and represent coeval transverse NW-SE shortening and vertical thinning. This implies that NE extension and southwest directed rollback of the active margin prevailed in the western Aegean between the Eocene and early Miocene.

Arsenic in Drinking Water and Lung Cancer Mortality in the United States: An Analysis Based on US Counties and 30 Years of Observation (1950–1979)

PubMed Central

Afari-Dwamena, Nana Ama; Li, Ji; Chen, Rusan; Feinleib, Manning; Lamm, Steven H.

2016-01-01

Background. To examine whether the US EPA (2010) lung cancer risk estimate derived from the high arsenic exposures (10–934 µg/L) in southwest Taiwan accurately predicts the US experience from low arsenic exposures (3–59 µg/L). Methods. Analyses have been limited to US counties solely dependent on underground sources for their drinking water supply with median arsenic levels of ≥3 µg/L. Results. Cancer risks (slopes) were found to be indistinguishable from zero for males and females. The addition of arsenic level did not significantly increase the explanatory power of the models. Stratified, or categorical, analysis yielded relative risks that hover about 1.00. The unit risk estimates were nonpositive and not significantly different from zero, and the maximum (95% UCL) unit risk estimates for lung cancer were lower than those in US EPA (2010). Conclusions. These data do not demonstrate an increased risk of lung cancer associated with median drinking water arsenic levels in the range of 3–59 µg/L. The upper-bound estimates of the risks are lower than the risks predicted from the SW Taiwan data and do not support those predictions. These results are consistent with a recent metaregression that indicated no increased lung cancer risk for arsenic exposures below 100–150 µg/L. PMID:27382373

Stratigraphy of Zambian copperbelt orebodies

NASA Astrophysics Data System (ADS)

Binda, Pier L.

1994-11-01

The subdivision of the Roan Supergroup in three informal units instead of the traditional Lower Roan/Upper Roan allows a better understanding of facies relationships. The lower division (Siliciclastic Unit) consists of a variable thickness of continental conglomerates and erenites. The middle division (Mixed Unit) consists of a wedge of carbonate and siliciclastic lithologies tapering to the south-west and deposited in a shallow sea. The upper division (Carbonate Unit or Upper Roan s.s.) is a thick succession of dolostones, subordinate argillites and breccias that directly overlies, but is probably in tectonic contact with, the Siliciclastic Unit in the south-western part of the Copperbelt. Reference boundaries for the Mixed and Siliciclastic Units are given for all mining localities of the Zambian Copperbelt. The basal part of the Mixed Unit, host to the most important CuCo orebodies, was deposited during a major marine transgression which, proceeding from SW-NE, swiftly inundated the whole Copperbelt basin. Thus, the Mufulira Ore Formation can be considered as the near-shore facies of the basinal ore shale. The transition from the Mufulira arenites to the Chambishi silty, ore shale has been effaced by erosional or tectonic stripping of the Roan sediments on the Kafue anticline, whereas the transition from silty to carbonaceous ore shale is well documented in the southern part of the Chambishi-Nkana basin. Concomitant with the NE-SW lithofacies changes within the basal Mixed Unit, there is marked decrease in Cu grade and content from the Mufulira wacke and arenite to the silty ore shale of the northern Chambishi basin and the carbonaceous and pyritic ore shale of the southern Chambishi basin. Cobalt is virtually absent in the Mufulira Ore Formation, reaches ore grade in the silty ore shale and occurs in trace amounts in the carbonaceous ore shale. Thus, the correlation of the basal Mixed Unit reveals a hitherto undetected regional metal zoning akin to that noted in parts of individual Copperbelt basin. The middle portion of the Mixed Unit contains at least one laterally continuous Cu mineralization in the arkosic arenite with minor occurrences of local significance. The Siliciclastic Unit contains Cu concentrations at several stratigraphical levels, but precise correlation of footwall orebodies is precluded by the heterogeneity of the clastic wedges of local provenance. The Mixed Unit of the Zambian Copperbelt can be correlated lithostratigraphically with the Serie des Mines of Shaba. A bed-by-bed correlation of the Kamoto (Zaire) and Mindola (Zambia) Ore Formations is proposed. The southern provenance of the Shaba nappes is supported.

The Grenville orogeny in the Llano Uplift, Texas: A record of collision and contraction along the southern margin of North America

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reese, J.F.

1993-02-01

Precambrian metamorphic rocks in the SE Llano Uplift record NE-directed ductile thrusting and regional-scale polyphase folding. This deformation is in response to Grenville-age shortening and crustal thickening associated with the collision of a south-lying tectonic block with the southern margin of North America. In the SE Llano Uplift, the most intense and pervasive deformational event, D2, is characterized in the Packsaddle Schist (PS) and Valley Spring Gneiss (VSG) by SSE-plunging, NE-verging isoclinal folds (F2) with an associated SW-dipping axial planar metamorphic layering (S2), and SW-dipping mylonite zones with kinematic indicators showing top-to-the-NE motion. In the Red Mountain and augen-bearing Bigmore » Branch gneisses, D2 structures are SW-dipping mylonite zones parallel to S2, and a SW-plunging stretching lineation. Taken together, this suite of structures indicates tectonic transport was to the NE, perpendicular to the NW trending regional structural and metamorphic grain. D2 structures were reoriented by at least two later phases of folding. Timing of all ductile deformation in the SE Llano Uplift is constrained from post-1,215 Ma (deformed PS) to pre-1,098 Ma (undeformed melarhyolite dike). From south to north, metatonalitic, arc-derived Big Branch Gneiss ([approximately] 1,303 Ma) and older mafic schist country rock, previously interpreted as possible ophiolitic melange, structurally overlie much younger, lithologically heterogeneous PS units (1,248-1,215 Ma), previously considered as arc flank deposits. In turn, the PS has been tectonically emplaced above the predominantly felsic VSG (1,270-1,232 Ma). The presence of older zircons in the VSG, of similar age ([approximately]1360 Ma) to Western Granite-Rhyolite Terrane rocks to the north, suggests that the VSG formed in a settling proximal to North America.« less

Histochemical and biochemical studies of carbonic anhydrase activity in the opercular epithelium of the euryhaline teleost, Fundulus heteroclitus.

PubMed

Lacy, E R

1983-01-01

Carbonic anhydrase (CAH) activity was biochemically measured and histochemically localized (at both the light and electron microscope levels) in isolated opercular membranes from teleost fish, Fundulus heteroclitus, adapted to freshwater (FW), seawater (SW), and double-strength seawater (2 x SW). The normal morphology of this membrane showed that its epithelial portion consisted of five cell types: (1) chloride cells, which have been previously implicated as responsible for the active chloride transport across the epithelium; (2) mucous cells; (3) pavement cells, which formed the major portion of the free epithelial surface; (4) supportive cells, which had an abundance of intermediate (10 nm)-type filaments suggesting a structural role for these cells; and (5) vesicular cells, which were characterized by various types of membrane-bound vesicles, including lysosomes, and numerous free ribosomes. Vesicular cells may be stem cells and/or endocrine cells. Hansson's histochemical method for CAH revealed cobalt sulfide reaction product confined to the following structures in fish from each environment: (1) chloride cells: throughout the cytoplasm and some nuclear staining; (2) mucous cells: throughout the cytoplasm, some nuclear staining, and some in mucous granules; (3) vesicular cells: confined to lysosomes, some of the vesicles, and nucleoli; (4) a small portion of the intracellular space between adjacent vesicular cells and supportive cells; and (5) supportive cells: in nucleoli and occasionally in larger membrane-bound lysosomelike structures. Acetazolamide (10(-5) M) and potassium cyanate (KCNO) (10(-1) M) in Hansson's incubation medium completely inhibited the formation of reaction product. Biochemical determination of CAH activity on vascularly perfused, isolated opercular membranes showed no statistically significant difference in enzyme activity between environmental groups. The following units of activity/mg opercular membrane protein were measured: FW: 0.63 +/- 0.02; SW: 0.43 +/- 0.08; 2 x SW: 0.64 +/- 0.09.

Evaluation of the oncolytic potential of R2B Mukteshwar vaccine strain of Newcastle disease virus (NDV) in a colon cancer cell line (SW-620).

PubMed

Sharma, Kishan K; Kalyani, Irsadullakhan H; Mohapatra, Jogeswar; Patel, Satish D; Patel, Dharmesh R; Vihol, Priti D; Chatterjee, Abhijit; Patel, Dinesh R; Vyas, Bhavesh

2017-09-01

Virotherapy is emerging as an alternative treatment of cancer. Among the candidate oncolytic viruses (OVs), Newcastle disease virus (NDV) has emerged as a promising non-engineered OV. In the present communication, we explored the oncolytic potential of R 2 B Mukteshwar strain of NDV using SW-620 colon cancer cells. SW-620 cells were xenografted in nude mice and after evaluation of the safety profile, 1 x 10 7 plaque forming units (PFU) of NDV were inoculated as virotherapeutic agent via the intratumoral (I/T) and intravenous (I/V) route. Tumor growth inhibition was compared with their respective control groups by gross volume and histopathological evaluation. Antibody titer and virus survival were measured by hemagglutination inhibition (HI)/serum neutralization test (SNT) and real-time PCR, respectively. During the safety trial, the test strain did not produce any abnormal symptoms nor weight loss in BALB/c mice. Significant tumor lytic activity was evident when viruses were injected via the I/T route. There was a 43 and 57% tumor growth inhibition on absolute and relative tumor volume basis, respectively, compared with mock control. On the same basis, the I/V route treatment resulted in 40 and 16% of inhibition, respectively. Histopathological examination revealed that the virus caused apoptosis, followed by necrosis, but immune cell infiltration was not remarkable. The virus survived in 2/2 mice until day 10 and in 3/6 mice by day 19, with both routes of administration. Anti-NDV antibodies were generated at moderate level and the titer reached a maximum of 1:32 and 1:64 via the I/T and I/V routes, respectively. In conclusion, the test NDV strain was found to be safe and showed oncolytic activity against the SW-620 cell line in mice.

SU-F-T-273: Using a Diode Array to Explore the Weakness of TPS DoseCalculation Algorithm for VMAT and Sliding Window Techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, J; Lu, B; Yan, G

Purpose: To identify the weakness of dose calculation algorithm in a treatment planning system for volumetric modulated arc therapy (VMAT) and sliding window (SW) techniques using a two-dimensional diode array. Methods: The VMAT quality assurance(QA) was implemented with a diode array using multiple partial arcs that divided from a VMAT plan; each partial arc has the same segments and the original monitor units. Arc angles were less than ± 30°. Multiple arcs delivered through consecutive and repetitive gantry operating clockwise and counterclockwise. The source-toaxis distance setup with the effective depths of 10 and 20 cm were used for a diodemore » array. To figure out dose errors caused in delivery of VMAT fields, the numerous fields having the same segments with the VMAT field irradiated using different delivery techniques of static and step-and-shoot. The dose distributions of the SW technique were evaluated by creating split fields having fine moving steps of multi-leaf collimator leaves. Calculated doses using the adaptive convolution algorithm were analyzed with measured ones with distance-to-agreement and dose difference of 3 mm and 3%.. Results: While the beam delivery through static and step-and-shoot techniques showed the passing rate of 97 ± 2%, partial arc delivery of the VMAT fields brought out passing rate of 85%. However, when leaf motion was restricted less than 4.6 mm/°, passing rate was improved up to 95 ± 2%. Similar passing rate were obtained for both 10 and 20 cm effective depth setup. The calculated doses using the SW technique showed the dose difference over 7% at the final arrival point of moving leaves. Conclusion: Error components in dynamic delivery of modulated beams were distinguished by using the suggested QA method. This partial arc method can be used for routine VMAT QA. Improved SW calculation algorithm is required to provide accurate estimated doses.« less

Intermediate regime and a phase diagram of red blood cell dynamics in a linear flow.

PubMed

Levant, Michael; Steinberg, Victor

2016-12-01

In this paper we investigate the in vitro dynamics of a single rabbit red blood cell (RBC) in a planar linear flow as a function of a shear stress σ and the dynamic viscosity of outer fluid η_{o}. A linear flow is a generalization of previous studies dynamics of soft objects including RBC in shear flow and is realized in the experiment in a microfluidic four-roll mill device. We verify that the RBC stable orientation dynamics is found in the experiment being the in-shear-plane orientation and the RBC dynamics is characterized by observed three RBC dynamical states, namely tumbling (TU), intermediate (INT), and swinging (SW) [or tank-treading (TT)] on a single RBC. The main results of these studies are the following. (i) We completely characterize the RBC dynamical states and reconstruct their phase diagram in the case of the RBC in-shear-plane orientation in a planar linear flow and find it in a good agreement with that obtained in early experiments in a shear flow for human RBCs. (ii) The value of the critical shear stress σ_{c} of the TU-TT(SW) transition surprisingly coincides with that found in early experiments in spite of a significant difference in the degree of RBC shape deformations in both the SW and INT states. (iii) We describe the INT regime, which is stationary, characterized by strong RBC shape deformations and observed in a wide range of the shear stresses. We argue that our observations cast doubts on the main claim of the recent numerical simulations that the only RBC spheroidal stress-free shape is capable to explain the early experimental data. Finally, we suggest that the amplitude dependence of both θ and the shape deformation parameter D on σ can be used as the quantitative criterion to determine the RBC stress-free shape.

Diversity and bioactivity of actinomycetes from marine sediments of the Yellow Sea

NASA Astrophysics Data System (ADS)

Zhang, Shumin; Ye, Liang; Tang, Xuexi

2012-03-01

Among the 116 actinomycetes collected from marine sediments of the Yellow Sea, 56 grew slowly and appeared after 2-3 weeks of incubation. Among the 56 strains, only 3 required seawater (SW) for growth, and 21 grew well in the medium prepared with SW rather than distilled water (DW), while the remaining 32 grew well either with SW or with DW. Six representatives with different morphological characteristics, including 1 SW-requiring strain and 5 well-growing with SW strains, were selected for phylogenetic analysis based on 16S rRNA gene. Two strains belong to Micrococcaceae and Nocardiopsaceae respectively. The other 4 strains belong to the family of Streptomycetaceae. In the analyzed 6 strains, one was related to Nocardiopsis spp. and the other three were related to Streptomyces spp., representing new taxa. Bioactivity testing of fermentation products from 3 SW-requiring strains and 21 well-growing with SW strains revealed that 17 strains possessed remarkable activities against gram-positive pathogen or/and tumor cells, suggesting that they were prolific resources for natural drug discovery.

Corrective Action Investigation Plan for Corrective Action Unit 428: Area 3 Septic Waste Systems 1 and 5, Tonopah Test Range, Nevada, REVISION 0, march 1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

ITLV.

1999-03-01

The Corrective Action Investigation Plan for Corrective Action Unit 428, Area 3 Septic Waste Systems 1 and 5, has been developed in accordance with the Federal Facility Agreement and Consent Order that was agreed to by the U. S. Department of Energy, Nevada Operations Office; the State of Nevada Division of Environmental Protection; and the U. S. Department of Defense. Corrective Action Unit 428 consists of Corrective Action Sites 03- 05- 002- SW01 and 03- 05- 002- SW05, respectively known as Area 3 Septic Waste System 1 and Septic Waste System 5. This Corrective Action Investigation Plan is used inmore » combination with the Work Plan for Leachfield Corrective Action Units: Nevada Test Site and Tonopah Test Range, Nevada , Rev. 1 (DOE/ NV, 1998c). The Leachfield Work Plan was developed to streamline investigations at leachfield Corrective Action Units by incorporating management, technical, quality assurance, health and safety, public involvement, field sampling, and waste management information common to a set of Corrective Action Units with similar site histories and characteristics into a single document that can be referenced. This Corrective Action Investigation Plan provides investigative details specific to Corrective Action Unit 428. A system of leachfields and associated collection systems was used for wastewater disposal at Area 3 of the Tonopah Test Range until a consolidated sewer system was installed in 1990 to replace the discrete septic waste systems. Operations within various buildings at Area 3 generated sanitary and industrial wastewaters potentially contaminated with contaminants of potential concern and disposed of in septic tanks and leachfields. Corrective Action Unit 428 is composed of two leachfield systems in the northern portion of Area 3. Based on site history collected to support the Data Quality Objectives process, contaminants of potential concern for the site include oil/ diesel range total petroleum hydrocarbons, and Resource Conservation and Recovery Act characteristic volatile organic compounds, semivolatile organic compounds, and metals. A limited number of samples will be analyzed for gamma- emitting radionuclides and isotopic uranium from four of the septic tanks and if radiological field screening levels are exceeded. Additional samples will be analyzed for geotechnical and hydrological properties and a bioassessment may be performed. The technical approach for investigating this Corrective Action Unit consists of the following activities: Perform video surveys of the discharge and outfall lines. Collect samples of material in the septic tanks. Conduct exploratory trenching to locate and inspect subsurface components. Collect subsurface soil samples in areas of the collection system including the septic tanks and outfall end of distribution boxes. Collect subsurface soil samples underlying the leachfield distribution pipes via trenching. Collect surface and near- surface samples near potential locations of the Acid Sewer Outfall if Septic Waste System 5 Leachfield cannot be located. Field screen samples for volatile organic compounds, total petroleum hydrocarbons, and radiological activity. Drill boreholes and collect subsurface soil samples if required. Analyze samples for total volatile organic compounds, total semivolatile organic compounds, total Resource Conservation and Recovery Act metals, and total petroleum hydrocarbons (oil/ diesel range organics). Limited number of samples will be analyzed for gamma- emitting radionuclides and isotopic uranium from particular septic tanks and if radiological field screening levels are exceeded. Collect samples from native soils beneath the distribution system and analyze for geotechnical/ hydrologic parameters. Collect and analyze bioassessment samples at the discretion of the Site Supervisor if total petroleum hydrocarbons exceed field- screening levels.« less

Philadelphia Infirmary for Nervous Diseases: America's original model of institutional neurology.

PubMed

Pappert, E J

1998-06-01

The role and contributions of the Philadelphia Orthopedic Hospital and Infirmary for Nervous Diseases in the development of neurology in 19th-century America are described. American neurology was largely born during the Civil War through the work of S.W. Mitchell at Turner's Lane Hospital. With the closing of this military facility, the United States was left without an institution dedicated to neurologic research and the treatment of nervous system diseases. Nineteenth century archival data, including original Trustees' minutes, annual board of managers reports, patient case books, and published research from the Philadelphia Orthopedic Hospital and Infirmary for Nervous Diseases were studied. The Philadelphia Orthopedic Hospital and Infirmary for Nervous Diseases promoted the development of neurology in the United States through three main activities. First, it offered patients with primary nervous system diseases, arthritis, and orthopedic disorders specialized care that was unavailable at medical universities. Second, its medical staff, especially Mitchell, provided opportunities for advanced neurologic education. Postgraduate physicians interested in neurologic disease attended formal lectures and directly participated in the operation of outpatient clinics and inpatient rounds. Finally, its formalized record system in the form of case books facilitated neurologic research. These records formed the basis of landmark publications by Mitchell, Sinkler, Osler, and others on rest therapy, spastic palsies, chorea, and other topics. As America's first and comprehensive peacetime neurologic facility, the Philadelphia Orthopedic Hospital and Infirmary for Nervous Diseases fostered the evolution of neurology as a separate, viable specialty in the post-Civil War period and provided a particular focus for the study of interactions among orthopedic, nutritional, and neurologic disorders.

Synthesis on Quaternary aeolian research in the unglaciated eastern United States

NASA Astrophysics Data System (ADS)

Markewich, Helaine W.; Litwin, Ronald J.; Wysocki, Douglas A.; Pavich, Milan J.

2015-06-01

Late-middle and late Pleistocene, and Holocene, inland aeolian sand and loess blanket >90,000 km2 of the unglaciated eastern United States of America (USA). Deposits are most extensive in the Lower Mississippi Valley (LMV) and Atlantic Coastal Plain (ACP), areas presently lacking significant aeolian activity. They provide evidence of paleoclimate intervals when wind erosion and deposition were dominant land-altering processes. This study synthesizes available data for aeolian sand deposits in the LMV, the Eastern Gulf Coastal Plain (EGCP) and the ACP, and loess deposits in the Middle Atlantic Coastal Plain (MACP). Data indicate: (a) the most recent major aeolian activity occurred in response to and coincident with growth and decay of the Laurentide Ice Sheet (LIS); (b) by ∼40 ka, aeolian processes greatly influenced landscape evolution in all three regions; (c) aeolian activity peaked in OIS2; (d) OIS3 and OIS2 aeolian records are in regional agreement with paleoecological records; and (e) limited aeolian activity occurred in the Holocene (EGCP and ACP). Paleoclimate and atmospheric-circulation models (PCMs/ACMs) for the last glacial maximum (LGM) show westerly winter winds for the unglaciated eastern USA, but do not resolve documented W and SW winds in the SEACP and WNW and N winds in the MACP. The minimum areal extent of aeolian deposits in the EGCP and ACP is ∼10,000 km2. For the LMV, it is >80,000 km2. Based on these estimates, published PCMs/ACMs likely underrepresent the areal extent of LGM aeolian activity, as well as the extent and complexity of climatic changes during this interval.

Seismic Waves, 4th order accurate

DOE Office of Scientific and Technical Information (OSTI.GOV)

2013-08-16

SW4 is a program for simulating seismic wave propagation on parallel computers. SW4 colves the seismic wave equations in Cartesian corrdinates. It is therefore appropriate for regional simulations, where the curvature of the earth can be neglected. SW4 implements a free surface boundary condition on a realistic topography, absorbing super-grid conditions on the far-field boundaries, and a kinematic source model consisting of point force and/or point moment tensor source terms. SW4 supports a fully 3-D heterogeneous material model that can be specified in several formats. SW4 can output synthetic seismograms in an ASCII test format, or in the SAC finarymore » format. It can also present simulation information as GMT scripts, whixh can be used to create annotated maps. Furthermore, SW4 can output the solution as well as the material model along 2-D grid planes.« less

Physiological preparedness and performance of Atlantic salmon Salmo salar smolts in relation to behavioural salinity preferences and thresholds

USGS Publications Warehouse

Stich, D.S.; Zydlewski, G.B.; Zydlewski, Joseph D.

2015-01-01

This study investigated the relationships between behavioural responses of Atlantic salmon Salmo salarsmolts to saltwater (SW) exposure and physiological characteristics of smolts in laboratory experiments. It concurrently described the behaviour of acoustically tagged smolts with respect to SW and tidal cycles during estuary migration. Salmo salar smolts increased their use of SW relative to fresh water (FW) from April to June in laboratory experiments. Mean preference for SW never exceeded 50% of time in any group. Preference for SW increased throughout the course of smolt development. Maximum continuous time spent in SW was positively related to gill Na+, K+-ATPase (NKA) activity and osmoregulatory performance in full-strength SW (measured as change in gill NKA activity and plasma osmolality). Smolts decreased depth upon reaching areas of the Penobscot Estuary where SW was present, and all fish became more surface oriented during passage from head of tide to the ocean. Acoustically tagged, migrating smolts with low gill NKA activity moved faster in FW reaches of the estuary than those with higher gill NKA activity. There was no difference in movement rate through SW reaches of the estuary based on gill NKA activity. Migrating fish moved with tidal flow during the passage of the lower estuary based on the observed patterns in both vertical and horizontal movements. The results indicate that smolts select low-salinity water during estuary migration and use tidal currents to minimize energetic investment in seaward migration. Seasonal changes in osmoregulatory ability highlight the importance of the timing of stocking and estuary arrival.

Skin whitening among Cameroonian female university students: knowledge, attitudes, practices and motivations.

PubMed

Kouotou, Emmanuel Armand; Nansseu, Jobert Richie N; Adegbidi, Hugues; Zoa Mebara, Theophane Christel Joel; Ndjitoyap Ndam, Elie Claude

2017-04-17

Lack of data on skin whitening (SW) among Cameroonian female university students prompted us to undertake the present study which aimed at assessing the knowledge, attitudes, practices and motivations of female university students vis-a-vis SW. This was a cross-sectional study conducted from January to April 2013 in 4 university campuses of Yaoundé, Cameroon. Any female student regularly registered in one of the study sites, who was present at the campus when the investigator visited and volunteered to participate in the study was enrolled. Overall, we recruited 620 female students, their ages ranging from 16 to 46 years with a mean of 21.3 ± 2.9 years. Only 87 participants (14%) found that SW was a good practice. One hundred and sixty nine respondents (27.3%) were currently practicing SW with no age difference when compared to their counterparts (p = 0.09). The desire to have a uniform body skin color was the prevailing reason motivating the practice of SW (39.1%), followed by the need to have a soft skin (29%). Assessment of levels of knowledge regarding advantages of the black skin and deleterious effects of SW showed excellent scores (≥75% of good answers) only in 6.1 and 0.5% of cases respectively, with no difference between those practicing SW or not (all p values > 0.05). The practice of SW is common among Cameroonian female university students who should therefore be educated on the advantages of the black skin and the harmful effects of SW.

Drainage-Area Data for Wisconsin Streams

DTIC Science & Technology

1983-01-01

Balsam Lake, County Trunk 34 N 16 W NW1/4SW1/4 11 Polk 5 81 .7 Highway E 05341000 Bone Lake near Luck (head of Fox Creek) 35 N 16 W NW1/4NW1/4 5 Polk 1...Not determine 05341010 Fox Creek near Luck, at outlet of Bone 35 N 16 W NW1/4SE1/4 20 Polk 7 16 .6 Lake 05341030 Straight River near Balsam Lake, at...13 W SW1/4SW1/4 21 Pepin 1 9,010 Eau Celle River 05369800 Eau Galle River tributary near Hersey, 28 N 15 W SW1/4SW1/4 5 St . Croix 3 .56 U.S

Development of Nautical Almanac at Korea Astronomy Observatory

NASA Astrophysics Data System (ADS)

Han, In-Woo; Shin, Junho

1994-12-01

In Korea Astronomy Observatory, we developed a S/W package to compile the Korean Nautical Almanac. We describe the motivation to develop the S/W and explain the S/W package in general terms. In appendix, we describe the procedure to calculate the polaris table in more detail. When we developed the S/W, we paid much attention to produce accurate data. We also made great effort to automate the compilation of Nautical Almanac as far as possible, since the compilation is time consuming labour extensive. As a result, the S/W we developed turns out to be very accurate and efficient to compile Nautical Almanac. In fact, we could compile a Korean Nautical Almanac in a few days.

Theoretical and Computational Studies of Condensed-Phase Phenomena: The Origin of Biological Homochirality, and the Liquid-Liquid Phase Transition in Network-Forming Fluids

NASA Astrophysics Data System (ADS)

Ricci, Francesco

This dissertation describes theoretical and computational studies of the origin of biological homochirality, and the existence of a liquid-liquid phase transition in pure-component network-forming fluids. A common theme throughout these studies is the use of sophisticated computer simulation and statistical mechanics techniques to study complex condensed-phase phenomena. In the first part of this dissertation, we use an elementary lattice model with molecular degrees of freedom, and satisfying microscopic reversibility, to investigate the effect of reaction reversibility on the evolution of stochastic symmetry breaking via autocatalysis and mutual inhibition in a closed system. We identify conditions under which the system's evolution towards racemic equilibrium becomes extremely slow, allowing for long-time persistence of a symmetry-broken state. We also identify a "monomer purification" mechanism, due to which a nearly homochiral state can persist for long times, even in the presence of significant reverse reaction rates. Order of magnitude estimates show that with reasonable physical parameters a symmetry broken state could persist over geologically-relevant time scales. In the second part of this dissertation, we study a chiral-symmetry breaking mechanism known as Viedma ripening. We develop a Monte Carlo model to gain further insights into the mechanisms capable of reproducing key experimental signatures associated with this phenomenon. We also provide a comprehensive investigation of how the model parameters impact the system's overall behavior. It is shown that size-dependent crystal solubility alone is insufficient to reproduce most experimental signatures, and that some form of a solid-phase chiral feedback mechanism (e.g., agglomeration) must be invoked in our model. In the third part of this dissertation, we perform rigorous free energy calculations to investigate the possibility of a liquid-liquid phase transition (LLPT) in the Stillinger-Weber (SW) model of silicon. A similar analysis is also presented for the generalized SW family of models by varying the "tetrahedrality" of the potential. Contrary to previously published findings, we do not find any evidence of the existence of an LLPT for SW silicon, nor for the generalized family of SW models over the range of parameters studied. Our results for the original parameterization of SW silicon are in semi-quantitative agreement with previous free energy calculations for this model, which were only provided at three state points. Explanations for the discrepancies between previous independent studies are provided, along with explicit demonstrations of how these discrepancies may have occurred. Finally, in the fourth part of this dissertation, we perform free energy calculations to demonstrate the existence of an LLPT in the Jagla potential. We also utilize finite-size scaling analysis to calculate the surface tension associated with the LLPT. In addition to the thermodynamics of the model, we investigate the relaxation times for density and bond-orientational order and show that, contrary to assertions in the literature, the characteristic relaxation time of bond-orientational order is not orders of magnitude slower than that of density. We compare our results for the Jagla model with those found in the literature for the ST2 model of water (which has also been rigorously shown to exhibit an LLPT) in order to emphasize key similarities and differences between two models that exhibit pure-component liquid-liquid phase separation.

Seawater inhalation induces acute lung injury via ROS generation and the endoplasmic reticulum stress pathway

PubMed Central

Li, Cong-Cong; Lu, Xi; Qian, Wei-Sheng; Li, Yu-Juan; Jin, Fa-Guang; Mu, De-Guang

2018-01-01

Seawater (SW) inhalation can induce acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). In the present study, SW induced apoptosis of rat alveolar epithelial cells and histopathological alterations to lung tissue. Furthermore, SW administration increased generation of reactive oxygen species (ROS), whereas pretreatment with the ROS scavenger, N-acetyl-L-cysteine (NAC), significantly decreased ROS generation, apoptosis and histopathological alterations. In addition, SW exposure upregulated the expression levels of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP), which are critical proteins in the endoplasmic reticulum (ER) stress response, thus indicating that SW may activate ER stress. Conversely, blocking ER stress with 4-phenylbutyric acid (4-PBA) significantly improved SW-induced apoptosis and histopathological alterations, whereas an ER stress inducer, thapsigargin, had the opposite effect. Furthermore, blocking ROS with NAC inhibited SW-induced ER stress, as evidenced by the downregulation of GRP78, phosphorylated (p)-protein kinase R-like ER kinase (PERK), p-inositol-requiring kinase 1α (IRE1α), p-50 activating transcription factor 6α and CHOP. In addition, blocking ER stress with 4-PBA decreased ROS generation. In conclusion, the present study indicated that ROS and ER stress pathways, which are involved in alveolar epithelial cell apoptosis, are important in the pathogenesis of SW-induced ALI. PMID:29436612

Ambient illumination switches contrast preference of specific retinal processing streams

PubMed Central

Pearson, James T.

2015-01-01

Contrast, a fundamental feature of visual scenes, is encoded in a distributed manner by ∼20 retinal ganglion cell (RGC) types, which stream visual information to the brain. RGC types respond preferentially to positive (ONpref) or negative (OFFpref) contrast and differ in their sensitivity to preferred contrast and responsiveness to nonpreferred stimuli. Vision operates over an enormous range of mean light levels. The influence of ambient illumination on contrast encoding across RGC types is not well understood. Here, we used large-scale multielectrode array recordings to characterize responses of mouse RGCs under lighting conditions spanning five orders in brightness magnitude. We identify three functional RGC types that switch contrast preference in a luminance-dependent manner (Sw1-, Sw2-, and Sw3-RGCs). As ambient illumination increases, Sw1- and Sw2-RGCs shift from ONpref to OFFpref and Sw3-RGCs from OFFpref to ONpref. In all cases, transitions in contrast preference are reversible and track light levels. By mapping spatiotemporal receptive fields at different mean light levels, we find that changes in input from ON and OFF pathways in receptive field centers underlie shifts in contrast preference. Sw2-RGCs exhibit direction-selective responses to motion stimuli. Despite changing contrast preference, direction selectivity of Sw2-RGCs and other RGCs as well as orientation-selective responses of RGCs remain stable across light levels. PMID:25995351

Dynamic properties of small-scale solar wind plasma fluctuations.

PubMed

Riazantseva, M O; Budaev, V P; Zelenyi, L M; Zastenker, G N; Pavlos, G P; Safrankova, J; Nemecek, Z; Prech, L; Nemec, F

2015-05-13

The paper presents the latest results of the studies of small-scale fluctuations in a turbulent flow of solar wind (SW) using measurements with extremely high temporal resolution (up to 0.03 s) of the bright monitor of SW (BMSW) plasma spectrometer operating on astrophysical SPECTR-R spacecraft at distances up to 350,000 km from the Earth. The spectra of SW ion flux fluctuations in the range of scales between 0.03 and 100 s are systematically analysed. The difference of slopes in low- and high-frequency parts of spectra and the frequency of the break point between these two characteristic slopes was analysed for different conditions in the SW. The statistical properties of the SW ion flux fluctuations were thoroughly analysed on scales less than 10 s. A high level of intermittency is demonstrated. The extended self-similarity of SW ion flux turbulent flow is constantly observed. The approximation of non-Gaussian probability distribution function of ion flux fluctuations by the Tsallis statistics shows the non-extensive character of SW fluctuations. Statistical characteristics of ion flux fluctuations are compared with the predictions of a log-Poisson model. The log-Poisson parametrization of the structure function scaling has shown that well-defined filament-like plasma structures are, as a rule, observed in the turbulent SW flows. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice.

PubMed

Metreveli, Giorgi; Gao, Qinshan; Mena, Ignacio; Schmolke, Mirco; Berg, Mikael; Albrecht, Randy A; García-Sastre, Adolfo

2014-08-08

Swine appear to be a key species in the generation of novel human influenza pandemics. Previous pandemic viruses are postulated to have evolved in swine by reassortment of avian, human, and swine influenza viruses. The human pandemic influenza viruses that emerged in 1957 and 1968 as well as swine viruses circulating since 1998 encode PB1 segments derived from avian influenza viruses. Here we investigate the possible role in viral replication and virulence of the PB1 gene segments present in two swine H1N2 influenza A viruses, A/swine/Sweden/1021/2009(H1N2) (sw 1021) and A/swine/Sweden/9706/2010(H1N2) (sw 9706), where the sw 1021 virus has shown to be more pathogenic in mice. By using reverse genetics, we swapped the PB1 genes of these two viruses. Similar to the sw 9706 virus, chimeric sw 1021 virus carrying the sw 9706 PB1 gene was not virulent in mice. In contrast, replacement of the PB1 gene of the sw 9706 virus by that from sw 1021 virus resulted in increased pathogenicity. Our study demonstrated that differences in virulence of swine influenza virus subtype H1N2 are attributed at least in part to the PB1 segment. Copyright © 2014 Elsevier B.V. All rights reserved.

The origin of the PB1 segment of swine influenza A virus subtype H1N2 determines viral pathogenicity in mice

PubMed Central

Metreveli, Giorgi; Gao, Qinshan; Mena, Nacho; Schmolke, Mirco; Berg, Mikael; Albrecht, Randy A.; García-Sastre, Adolfo

2017-01-01

Swine appear to be a key species in the generation of novel human influenza pandemics. Previous pandemic viruses are postulated to have evolved in swine by reassortment of avian, human, and swine influenza viruses. The human pandemic influenza viruses that emerged in 1957 and 1968 as well as swine viruses circulating since 1998 encode PB1 segments derived from avian influenza viruses. Here we investigate the possible role in viral replication and virulence of the PB1 gene segments present in two swine H1N2 influenza A viruses, A/swine/Sweden/1021/2009(H1N2) (sw 1021) and A/swine/Sweden/9706/2010(H1N2) (sw 9706), where the sw 1021 virus has shown to be more pathogenic in mice. By using reverse genetics, we swapped the PB1 genes of these two viruses. Similar to the sw 9706 virus, chimeric sw 1021 virus carrying the sw 9706 PB1 gene was not virulent in mice. In contrast, replacement of the PB1 gene of the sw 9706 virus by that from sw 1021 virus resulted in increased pathogenicity. Our study demonstrated that differences in virulence of swine influenza virus subtype H1N2 are attributed at least in part to the PB1 segment. PMID:24726997

Simulation of Oscillatory Domain Wall Motion Driven by Spin Waves in Nanostrip with Perpendicular Magnetic Anisotropy

NASA Astrophysics Data System (ADS)

Lee, Shang Fan; Chang, Liang Juan; Spintronics Laboratory Team

2014-03-01

We numerically investigate the spin waves (SW) induced domain wall (DW) oscillatory motion in a nanostrip with perpendicular magnetic anisotropy by means of micromagnetic simulation. SW carries spin angular momentum and can interact with DWs via Spin Transfer Torque (STT). Propagating SW can drive a DW motion depending on the in-plane tilt angle φ of the wall magnetization. We calculate the instantaneous velocity of DWs as a function of φwith different SW frequency f. We find that the DW motion under propagating SW depends not only on the frequencies f, but also on the in-plane tilt angle φ. The nanostrip considered is 50 nm wide and 4000 nm long. A DW at the center is subjected to a SW source 500 nm apart on the left with amplitude in the transverse direction and varying frequency f. The motions of the DW induced by the SW are accompanied by in-plane rotation of magnetization of DW. Once rotated by 90 degrees, the DW shows a backward motion towards the SW source. The oscillatory amplitude and frequency of the DW motion is analyzed. A phase diagram will be presented. This study provides new perspectives for the control and manipulation of DW in a nanostrip. Financial supports by Academia Sinica and National Science Council are acknowledged

Healthcare program for sex workers: a public health priority.

PubMed

Marin, Gustavo; Silberman, Martin; Martinez, Susana; Sanguinetti, Carlos

2015-01-01

The objective of this study was to propose a model of health care for sexual workers (SWs) and transvestites (Ts) groups who were historically excluded from health services. A prospective descriptive/analytical study with an intervention stage was performed, focusing on the health status of SWs and Ts. Access to health system, inclusion into social programs, beneficiaries' participation, and rate of risk behaviors were variables measured before and after intervention that consist in a program based on promotion/prevention activities and complete health care service suitable to SW-T needs. Nine hundred and fifty SW-Ts were included. At baseline, 99.7% lacked health insurance and 90.1% had no access to the health care. These data were compared with those obtained after attention quadruplicated among SW because of the implementation of the program. Risky sexual behaviors were reduced by 25 times. SWs have their own leader of health institutions and coordinate themselves with the program's activities. Responsibility of the state's authorities on vulnerable groups must focus on their inclusion. To this end, health services must adapt themselves in order to attend those community groups with special needs. Active participation of the target population contributes to viability of this type of proposals, and it is essential for the project's success. Copyright © 2013 John Wiley & Sons, Ltd.

Transmission of influenza A viruses between pigs and people, Iowa, 2002-2004.

PubMed

Terebuh, Pauline; Olsen, Christopher W; Wright, Jennifer; Klimov, Alexander; Karasin, Alexander; Todd, Karla; Zhou, Hong; Hall, Henrietta; Xu, Xiyan; Kniffen, Tim; Madsen, David; Garten, Rebecca; Bridges, Carolyn B

2010-11-01

Triple-reassortant (tr) viruses of human, avian, and swine origin, including H1N1, H1N2, and H3N2 subtypes, emerged in North American swine herds in 1998 and have become predominant. While sporadic human infections with classical influenza A (H1N1) and with tr-swine influenza viruses have been reported, relatively few have been documented in occupationally exposed swine workers (SW). We conducted a 2-year (2002-2004) prospective cohort study of transmission of influenza viruses between pigs and SW from a single pork production company in Iowa. Respiratory samples were collected and tested for influenza viruses from SW and from pigs under their care through surveillance for influenza-like illnesses (ILI). Serial blood samples from study participants were tested by hemagglutination inhibition (HI) for antibody seroconversion against human and swine influenza viruses (SIV), and antibody seroprevalence was compared to age-matched urban Iowa blood donors. During the first year, 15 of 88 SW had ILI and were sampled; all were culture-negative for influenza. During the second year, 11 of 76 SW had ILI and were sampled; one was culture-positive for a human seasonal H3N2 virus. Among 20 swine herd ILI outbreaks sampled, influenza A virus was detected by rRT-PCR from 17 with 11 trH1N1 and five trH3N2 virus isolates cultured. During both years, HI geometric mean titers were significantly higher among SW compared to blood donor controls for three SIV: classical swine Sw/WI/238/97 (H1N1), tr Sw/IN/9K035/99 (H1N2), and trSw/IA/H02NJ56371/02 (H1N1)] (P < 0·0001). SW had serologic evidence for infection with both swine and human influenza viruses and were exposed to diverse influenza virus strains circulating in pigs. Influenza virus surveillance among pigs and SW should be encouraged to better understand cross-species transmission and diversity of influenza viruses at the human-swine interface. © 2010 Blackwell Publishing Ltd.

77 FR 33704 - Inviting Applications for Rural Business Opportunity Grants

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-07

... Development State Office, 1835 Black Lake Boulevard SW., Suite B, Olympia, WA 98512-5715, (360) 704-7740/TDD... at (202) 720-2600 (voice and TDD). To file a complaint of discrimination, write to USDA, Director...-9410 or call (800) 795-3272 (voice) or (202) 720-6382 (TDD). USDA is an equal opportunity provider and...

75 FR 31413 - Notice of Funding Availability (NOFA) Inviting Applications for the Rural Microentrepreneur...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

... Rural Development State Office, 1835 Black Lake Boulevard SW., Suite B, Olympia, WA 98512-5715, (360... TARGET Center at (202) 720-2600 (voice and TDD). To file a complaint of discrimination write to USDA... or call (800) 795-3272 (voice) or (202) 720-6382 (TDD). USDA is an equal opportunity provider...

Impacts of climate change on Southwestern working lands and water resources: a report from the inaugural year of the USDA Southwest climate hub

USDA-ARS?s Scientific Manuscript database

In February 2014 the USDA established seven regional climate hubs to assist farmers, ranchers and foresters in adapting to the effects of climate change. The SW region encompasses six states (including Hawaii) and provides highly diverse agricultural crops including cotton, stone fruit and grapes. ...

75 FR 17303 - Section 108 Community Development Loan Guarantee Program: Participation of States as Borrowers...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT 24 CFR Part 570 [Docket No. 5326-F-02] RIN 2506-AC28... Division, Office of Community Planning and Development, Department of Housing and Urban Development, 451... Division, Office of General Counsel, Department of Housing and Urban Development, 451 7th Street, SW., Room...

109(b) State Training Center Facility Assessment, Program Evaluation, and Guide Development. Final Report.

ERIC Educational Resources Information Center

Miklas, Michael P., Jr.

Section 109(b) of the 1972 Federal Water Pollution Control Act Amendments authorized funding for the construction of statewide water treatment training facilities. Described in this report is work conducted by Southwest Research Institute (SwRI) to: (1) aid in developing updated 109(b) Guidance Documents; (2) characterize and evaluate existing…

Characterization of free-standing InAs quantum membranes by standing wave hard x-ray photoemission spectroscopy

NASA Astrophysics Data System (ADS)

Conti, G.; Nemšák, S.; Kuo, C.-T.; Gehlmann, M.; Conlon, C.; Keqi, A.; Rattanachata, A.; Karslıoǧlu, O.; Mueller, J.; Sethian, J.; Bluhm, H.; Rault, J. E.; Rueff, J. P.; Fang, H.; Javey, A.; Fadley, C. S.

2018-05-01

Free-standing nanoribbons of InAs quantum membranes (QMs) transferred onto a (Si/Mo) multilayer mirror substrate are characterized by hard x-ray photoemission spectroscopy (HXPS) and by standing-wave HXPS (SW-HXPS). Information on the chemical composition and on the chemical states of the elements within the nanoribbons was obtained by HXPS and on the quantitative depth profiles by SW-HXPS. By comparing the experimental SW-HXPS rocking curves to x-ray optical calculations, the chemical depth profile of the InAs(QM) and its interfaces were quantitatively derived with ångström precision. We determined that (i) the exposure to air induced the formation of an InAsO4 layer on top of the stoichiometric InAs(QM); (ii) the top interface between the air-side InAsO4 and the InAs(QM) is not sharp, indicating that interdiffusion occurs between these two layers; (iii) the bottom interface between the InAs(QM) and the native oxide SiO2 on top of the (Si/Mo) substrate is abrupt. In addition, the valence band offset (VBO) between the InAs(QM) and the SiO2/(Si/Mo) substrate was determined by HXPS. The value of VBO = 0.2 ± 0.04 eV is in good agreement with literature results obtained by electrical characterization, giving a clear indication of the formation of a well-defined and abrupt InAs/SiO2 heterojunction. We have demonstrated that HXPS and SW-HXPS are non-destructive, powerful methods for characterizing interfaces and for providing chemical depth profiles of nanostructures, quantum membranes, and 2D layered materials.

Rearing Mozambique tilapia in tidally-changing salinities: Effects on growth and the growth hormone/insulin-like growth factor I axis.

PubMed

Moorman, Benjamin P; Yamaguchi, Yoko; Lerner, Darren T; Grau, E Gordon; Seale, Andre P

2016-08-01

The growth hormone (GH)/insulin-like growth factor (IGF) axis plays a central role in the regulation of growth in teleosts and has been shown to be affected by acclimation salinity. This study was aimed at characterizing the effects of rearing tilapia, Oreochromis mossambicus, in a tidally-changing salinity on the GH/IGF axis and growth. Tilapia were raised in fresh water (FW), seawater (SW), or in a tidally-changing environment, in which salinity is switched between FW (TF) and SW (TS) every 6h, for 4months. Growth was measured over all time points recorded and fish reared in a tidally-changing environment grew significantly faster than other groups. The levels of circulating growth hormone (GH), insulin-like growth factor I (IGF-I), pituitary GH mRNA, gene expression of IGF-I, IGF-II, and growth hormone receptor 2 (GHR) in the muscle and liver were also determined. Plasma IGF-I was higher in FW and TS than in SW and TF tilapia. Pituitary GH mRNA was higher in TF and TS than in FW and SW tilapia. Gene expression of IGF-I in the liver and of GHR in both the muscle and liver changed between TF and TS fish. Fish growth was positively correlated with GH mRNA expression in the pituitary, and GHR mRNA expression in muscle and liver tissues. Our study indicates that rearing fish under tidally-changing salinities elicits a distinct pattern of endocrine regulation from that observed in fish reared in steady-state conditions, and may provide a new approach to increase tilapia growth rate and study the regulation of growth in euryhaline fish. Copyright © 2016 Elsevier Inc. All rights reserved.

Solar radiation and street temperature as function of street orientation. An analysis of the status quo and simulation of future scenarios towards sustainability in Bahrain

NASA Astrophysics Data System (ADS)

Silva, Joao Pinelo

2017-11-01

This paper discusses the contribution of street orientation towards the development of a comfortable microclimate for pedestrians in Bahrain. Increasing walkability is a global agenda to address issues such as a) transportation, b) energy consumption, c) health, and d) air pollution, all of which are topics of the sustainability agenda. Thermal comfort is one of the pre-requisites for walkability. In warm climates, this is a challenging goal. Street design is paramount for pedestrian comfort in warm climates. The roles of street orientation and aspect ratio are of particular importance as they determine the intake of solar radiation into the urban canyon. We investigate the state of affairs in Bahrain, by measuring the frequency with which the street orientations E-W, N-S, NE-SW, and NW-SE, currently occur. Research suggests that the street orientation E-W presents the lesser performance for mitigating the effects of heat gain. The ideal grid orientation would, therefore, be N-S, and NE-SW - NW-SE, avoiding street segments with E-W orientation. A countrywide analysis shows that E-W orientation accounts for the highest overall street length with 37%. The second most frequent orientation is N-S (29%), the best performer. NW-SE and NE-SW both have frequencies of only 17%. Preference for a street grid with N-S, NW-SE, and NE-SW orientation would improve the thermal performance of streets and provide a continuous network of a comfortable pedestrian environment. We simulate two future scenarios based on avoiding new E-W streets, or not. We measure their potential reduction in thermal gain and conclude that a simple policy could reduce solar exposition in 40%.

Salinity Effects on Strategies of Glycogen Utilization in Livers of Euryhaline Milkfish (Chanos chanos) under Hypothermal Stress

PubMed Central

Chang, Chia-Hao; Huang, Jian-Jun; Yeh, Chun-Yi; Tang, Cheng-Hao; Hwang, Lie-Yueh; Lee, Tsung-Han

2018-01-01

The fluctuation of temperature affects many physiological responses in ectothermic organisms, including feed intake, growth, reproduction, and behavior. Changes in environmental temperatures affect the acquisition of energy, whereas hepatic glycogen plays a central role in energy supply for the homeostasis of the entire body. Glycogen phosphorylase (GP), which catalyzes the rate-limiting step in glycogenolysis, is also an indicator of environmental stress. Here, we examined the effects of salinity on glycogen metabolism in milkfish livers under cold stress. A reduction of feed intake was observed in both freshwater (FW) and seawater (SW) milkfish under cold adaptation. At normal temperature (28°C), compared to the FW milkfish, the SW milkfish exhibited greater mRNA abundance of the liver isoform of GP (Ccpygl), higher GP activity, and less glycogen content in the livers. Upon hypothermal (18°C) stress, hepatic Ccpygl mRNA expression of FW milkfish surged at 3 h, declined at 6 and 12 h, increased again at 24 h, and increased significantly after 96 h. Increases in GP protein, GP activity, and the phosphorylation state and the breakdown of glycogen were also found in FW milkfish livers after 12 h of exposure at 18°C. Conversely, the Ccpygl transcript levels in SW milkfish were downregulated after 1 h of exposure at 18°C, whereas the protein abundance of GP, GP activity, and glycogen content were not significantly altered. Taken together, under 18°C cold stress, FW milkfish exhibited an acute response with the breakdown of hepatic glycogen for maintaining energy homeostasis of the entire body, whereas no change was observed in the hepatic glycogen content and GP activity of SW milkfish because of their greater tolerance to cold conditions. PMID:29483878

Salinity Effects on Strategies of Glycogen Utilization in Livers of Euryhaline Milkfish (Chanos chanos) under Hypothermal Stress.

PubMed

Chang, Chia-Hao; Huang, Jian-Jun; Yeh, Chun-Yi; Tang, Cheng-Hao; Hwang, Lie-Yueh; Lee, Tsung-Han

2018-01-01

The fluctuation of temperature affects many physiological responses in ectothermic organisms, including feed intake, growth, reproduction, and behavior. Changes in environmental temperatures affect the acquisition of energy, whereas hepatic glycogen plays a central role in energy supply for the homeostasis of the entire body. Glycogen phosphorylase (GP), which catalyzes the rate-limiting step in glycogenolysis, is also an indicator of environmental stress. Here, we examined the effects of salinity on glycogen metabolism in milkfish livers under cold stress. A reduction of feed intake was observed in both freshwater (FW) and seawater (SW) milkfish under cold adaptation. At normal temperature (28°C), compared to the FW milkfish, the SW milkfish exhibited greater mRNA abundance of the liver isoform of GP ( Ccpygl ), higher GP activity, and less glycogen content in the livers. Upon hypothermal (18°C) stress, hepatic Ccpygl mRNA expression of FW milkfish surged at 3 h, declined at 6 and 12 h, increased again at 24 h, and increased significantly after 96 h. Increases in GP protein, GP activity, and the phosphorylation state and the breakdown of glycogen were also found in FW milkfish livers after 12 h of exposure at 18°C. Conversely, the Ccpygl transcript levels in SW milkfish were downregulated after 1 h of exposure at 18°C, whereas the protein abundance of GP, GP activity, and glycogen content were not significantly altered. Taken together, under 18°C cold stress, FW milkfish exhibited an acute response with the breakdown of hepatic glycogen for maintaining energy homeostasis of the entire body, whereas no change was observed in the hepatic glycogen content and GP activity of SW milkfish because of their greater tolerance to cold conditions.

Optimized equation of the state of the square-well fluid of variable range based on a fourth-order free-energy expansion.

PubMed

Espíndola-Heredia, Rodolfo; del Río, Fernando; Malijevsky, Anatol

2009-01-14

The free energy of square-well (SW) systems of hard-core diameter sigma with ranges 1 < or = lambda < or = 3 is expanded in a perturbation series. This interval covers most ranges of interest, from short-ranged SW fluids (lambda approximately 1.2) used in modeling colloids to long ranges (lambda approximately 3) where the van der Waals classic approximation holds. The first four terms are evaluated by means of extensive Monte Carlo simulations. The calculations are corrected for the thermodynamic limit and care is taken to evaluate and to control the various sources of error. The results for the first two terms in the series confirm well-known independent results but have an increased estimated accuracy and cover a wider set of well ranges. The results for the third- and fourth-order terms are novel. The free-energy expansion for systems with short and intermediate ranges, 1 < or = lambda < or = 2, is seen to have properties similar to those of systems with longer ranges, 2 < or = lambda < or = 3. An equation of state (EOS) is built to represent the free-energy data. The thermodynamics given by this EOS, confronted against independent computer simulations, is shown to predict accurately the internal energy, pressure, specific heat, and chemical potential of the SW fluids considered and for densities 0 < or = rho sigma(3) < or = 0.9 including subcritical temperatures. This fourth-order theory is estimated to be accurate except for a small region at high density, rho sigma(3) approximately 0.9, and low temperature where terms of still higher order might be needed.

Successional Distance between the Source and Recipient Influence Seed Germination and Seedling Survival during Surface Soil Replacement in SW China

PubMed Central

Shen, You-xin; Gao, Lei; Xia, Xue; Li, Yuhui; Guan, Huilin

2013-01-01

Adding propagules (source) to a degraded site (recipient) is a common way of manipulating secondary succession to restore diversity and services formerly provided by forests. However, heretofore no study has considered the effect of “successional distance” between source and recipient site. Four sites in the Shilin karst area of SW China were treated as different states along a secondary successional sere: grass, shrub, young secondary forest, and primary forest. Ten 1 m ×1m soil quadrats in the grass, shrub and young forest sites were replaced with 10 cm deep soil sources from corresponding later successional stage(s) in January 2009. Woody plant seed germination was monitored in the first year and seedling survival was monitored until the end of the second year. At the end of 2010, 2097 seeds of woody plants belonging to 45 taxa had germinated, and 3.9% of the seedlings and 7.8% of the species survived. Germination of most species was sensitive to ambient light (red, far-red, R:FR ratios, photosynthetically active radiation). Soil source and recipient site had a significant effect on the total number of seeds and number of species that germinated, and on the percentage of seedlings that survived through the end of the second year. Closer successional stages between recipient site and soil source had higher seed germination and seedling-survival percentages. However, a transition threshold exists in the young forest state, where seeds can germinate but not survive the second year. Our results, although based on an unreplicated chronosequence, suggest that successional distance between soil sources and recipient sites affect forest recruitment and restoration in degraded karst of SW China. PMID:24223891

Risk-taking behaviours and HIV infection among sex workers in Portugal: results from a cross-sectional survey.

PubMed

Dias, Sónia; Gama, Ana; Fuertes, Ricardo; Mendão, Luís; Barros, Henrique

2015-08-01

Sex workers (SW) are key populations at an increased risk of HIV infection. This study aimed to characterise risk-taking behaviours and assess HIV prevalence among SW in Portugal. A cross-sectional survey was conducted with 1040 SW using a participatory research approach. SW were recruited in sex-work locations and community-based organisation offices. Data were collected through a questionnaire with trained interviewers. An HIV rapid test was performed in 213 respondents. Reported HIV prevalence was 8%: 17.6% of man-to-woman transgenders, 7.4% of women and 5% of men. Of SW reportedly living with HIV, 52.2% reported ever injecting drug use. Inconsistent condom use with clients in the last month was higher among male SW (26.5%) and with non-paying partners in the last year was higher among women (71.3%). Among reported HIV-positive SW, the proportions of inconsistent condom use were high. In multivariate regression analysis, reported HIV infection remained significantly higher among transgenders (OR 6.4; 95% CI 1.7 to 24.3), those older (OR 5.1; 95% CI 1.3 to 21.1), working outdoors (OR 5.4; 95% CI 1.9 to 15.6), having ever used psychoactive substances (OR 4.1; 95% CI 2.2 to 7.7) and earning ≤€1000 per month (OR 2.6; 95% CI 1.2 to 5.9). Of those who had an HIV rapid test, 8.9% were reactive; 73.7% were unaware of their seropositivity. The HIV infection burden in SW is high. Efforts to promote HIV testing must be sustained in order to reduce undiagnosed infection. The diverse risk profiles of SW must be addressed in targeted HIV interventions. Prevention interventions should be systematically implemented within most-at-risk subgroups of SW. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

The formation of lipid droplets favors intracellular Mycobacterium leprae survival in SW-10, non-myelinating Schwann cells.

PubMed

Jin, Song-Hyo; An, Sung-Kwan; Lee, Seong-Beom

2017-06-01

Leprosy is a chronic infectious disease that is caused by the obligate intracellular pathogen Mycobacterium leprae (M.leprae), which is the leading cause of all non-traumatic peripheral neuropathies worldwide. Although both myelinating and non-myelinating Schwann cells are infected by M.leprae in patients with lepromatous leprosy, M.leprae preferentially invades the non-myelinating Schwann cells. However, the effect of M.leprae infection on non-myelinating Schwann cells has not been elucidated. Lipid droplets (LDs) are found in M.leprae-infected Schwann cells in the nerve biopsies of lepromatous leprosy patients. M.leprae-induced LD formation favors intracellular M.leprae survival in primary Schwann cells and in a myelinating Schwann cell line referred to as ST88-14. In the current study, we initially characterized SW-10 cells and investigated the effects of LDs on M.leprae-infected SW-10 cells, which are non-myelinating Schwann cells. SW-10 cells express S100, a marker for cells from the neural crest, and NGFR p75, a marker for immature or non-myelinating Schwann cells. SW-10 cells, however, do not express myelin basic protein (MBP), a marker for myelinating Schwann cells, and myelin protein zero (MPZ), a marker for precursor, immature, or myelinating Schwann cells, all of which suggests that SW-10 cells are non-myelinating Schwann cells. In addition, SW-10 cells have phagocytic activity and can be infected with M. leprae. Infection with M. leprae induces the formation of LDs. Furthermore, inhibiting the formation of M. leprae-induced LD enhances the maturation of phagosomes containing live M.leprae and decreases the ATP content in the M. leprae found in SW-10 cells. These facts suggest that LD formation by M. leprae favors intracellular M. leprae survival in SW-10 cells, which leads to the logical conclusion that M.leprae-infected SW-10 cells can be a new model for investigating the interaction of M.leprae with non-myelinating Schwann cells.

The formation of lipid droplets favors intracellular Mycobacterium leprae survival in SW-10, non-myelinating Schwann cells

PubMed Central

Jin, Song-Hyo; An, Sung-Kwan

2017-01-01

Leprosy is a chronic infectious disease that is caused by the obligate intracellular pathogen Mycobacterium leprae (M.leprae), which is the leading cause of all non-traumatic peripheral neuropathies worldwide. Although both myelinating and non-myelinating Schwann cells are infected by M.leprae in patients with lepromatous leprosy, M.leprae preferentially invades the non-myelinating Schwann cells. However, the effect of M.leprae infection on non-myelinating Schwann cells has not been elucidated. Lipid droplets (LDs) are found in M.leprae-infected Schwann cells in the nerve biopsies of lepromatous leprosy patients. M.leprae-induced LD formation favors intracellular M.leprae survival in primary Schwann cells and in a myelinating Schwann cell line referred to as ST88-14. In the current study, we initially characterized SW-10 cells and investigated the effects of LDs on M.leprae-infected SW-10 cells, which are non-myelinating Schwann cells. SW-10 cells express S100, a marker for cells from the neural crest, and NGFR p75, a marker for immature or non-myelinating Schwann cells. SW-10 cells, however, do not express myelin basic protein (MBP), a marker for myelinating Schwann cells, and myelin protein zero (MPZ), a marker for precursor, immature, or myelinating Schwann cells, all of which suggests that SW-10 cells are non-myelinating Schwann cells. In addition, SW-10 cells have phagocytic activity and can be infected with M. leprae. Infection with M. leprae induces the formation of LDs. Furthermore, inhibiting the formation of M. leprae-induced LD enhances the maturation of phagosomes containing live M.leprae and decreases the ATP content in the M. leprae found in SW-10 cells. These facts suggest that LD formation by M. leprae favors intracellular M. leprae survival in SW-10 cells, which leads to the logical conclusion that M.leprae-infected SW-10 cells can be a new model for investigating the interaction of M.leprae with non-myelinating Schwann cells. PMID:28636650

Cytokinin profiles in ex vitro acclimatized Eucomis autumnalis plants pre-treated with smoke-derived karrikinolide.

PubMed

Aremu, Adeyemi O; Plačková, Lenka; Novák, Ondřej; Stirk, Wendy A; Doležal, Karel; Van Staden, Johannes

2016-01-01

The current evidence of regulatory effect of smoke-water (SW) and karrikinolide (KAR(1)) on the concentrations of endogenous cytokinins in plants partly explain the basis for their growth stimulatory activity. Karrikinolide (KAR1) which is derived from smoke-water (SW) is involved in some physiological aspects in the life-cycle of plants. This suggests a potential influence on the endogenous pool (quantity and quality) of phytohormones such as cytokinins (CKs). In the current study, the effect of SW (1:500; 1:1000; 1:1500 v/v dilutions) and KAR1 (10(-7); 10(-8); 10(-9) M) applied during micropropagation of Eucomis autumnalis subspecies autumnalis on the ex vitro growth and CKs after 4 months post-flask duration was evaluated. The interactions of SW and KAR(1) with benzyladenine (BA), α-naphthaleneacetic acid (NAA) or BA+NAA were also assessed. Plants treated with SW (1:500) and KAR1 (10(-8) M) demonstrated superior growth in terms of the rooting, leaf and bulb sizes and fresh biomass than the control and plants treated with BA and BA+NAA. However, plant growth was generally inhibited with either SW (1:500) or KAR1 (10(-8) M) and BA when compared to BA (alone) treatment. Relative to NAA treatment, the presence of KAR(1) (10(-7) M) with NAA significantly increased the leaf area and fresh biomass. Both SW and KAR1-treated plants accumulated more total CKs, mainly isoprenoid-type than the control and NAA-treated plants. The highest CK content was also accumulated in SW (1:500) with BA+NAA treatments. Similar stimulatory effects were observed with increasing concentrations of KAR(1) and BA. The current findings establish that SW and KAR1 exert significant influence on the endogenous CK pools. However, the better growth of plants treated with SW and KAR1 treatments was not exclusively related to the endogenous CKs.

Effects of environmental salinity and 17alpha-methyltestosterone on growth and oxygen consumption in the tilapia, Oreochromis mossambicus.

PubMed

Sparks, Russell T; Shepherd, Brian S; Ron, Benny; Harold Richman, N; Riley, Larry G; Iwama, George K; Hirano, Tetsuya; Gordon Grau, E

2003-12-01

Effects of environmental salinity and 17alpha-methyltestosterone (MT) on growth and oxygen consumption were examined in the tilapia, Oreochromis mossambicus. Yolk-sac fry were collected from brood stock in fresh water (FW). After yolk-sac absorption, they were assigned randomly to one of four groups: FW, MT treatment in FW, seawater (SW) and MT treatment in SW. All treatment groups were fed to satiation three times daily. The fish reared in SW (both control and MT-treated groups) grew significantly larger than either group in FW from day 43 throughout the experiment (195 days). The fish fed with MT added to their feed grew significantly larger than their respective controls from day 85 in FW and in SW until the end of the experiment. The routine metabolic rate (RMR) was determined monthly from month 2 (day 62) to month 5 (day 155). A significant negative correlation was seen between RMR and body mass in all treatment groups. Among fish of the same age, the SW-reared tilapia had significantly lower RMRs than the FW-reared fish. The MT-treated fish in SW showed significantly lower RMRs than the SW control group at months 3-5, whereas MT treatment in FW significantly increased the RMR at month 3. Comparison of regression lines between RMR and body mass indicates that MT treatment in FW caused a significant increase in oxygen consumption at a given mass of the fish, whereas MT treatment was without effect on RMR in SW-reared fish. These results clearly indicate that SW-rearing and MT treatment accelerate growth of tilapia, and that RMR decreases as fish size increased. It is also likely that the increased RMR and growth in MT-treated tilapia in FW may be due to the metabolic actions of MT, although the reason for the absence of MT treatment in SW is unclear.

Pyroconvection and Climate Change

DTIC Science & Technology

2007-01-01

Climate Change 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Research Laboratory,4555 Overlook Avenue SW,Washington,DC,20375 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited

Unmanned Vehicles Systems; Unmanned Vehicle Tactical Memorandum (TM 3-22-5-SW): Report of Findings and Recommendation

DTIC Science & Technology

2007-01-31

FP) missions. These missions are broadly categorized by sizes and associated platforms (not all inclusive) as shown in Table 2. UAV greater than...initiative and the Marines’ interim small unit remote scouting system (I-SURSS) requirement. The potential Navy version is referred to as Sea ALL . Dragon...wingspan, about seven inches long) that can stay in the air for about an hour. Once the battery powered propeller is spinning, the operator throws

Investigation of Hydrophobic Radomes for Microwave Landing System.

DTIC Science & Technology

1982-11-01

horizontal heating wires on the inside surface, and 2) a slotted waveguide unit (C-band waveguide, about 2 feet in length) covered with a Teflon shrink tube ...AZ) Fiberglass flat 1.5ft x 13ft NE sandwich (EL) Teflon shrink 1 in x 2 ft SW tubing (Field Mon.) 7 (8) Hydrophobic Coating for Antenna Weather...SURFACE PREPARATION 13 24 Mar 󈨖 Conolite Primer: Vellox S-048 Finish: Microfine FSD, 7 coats, sprayed 14 24 Mar 󈨖 Conolite Teflon film, C-TAPE-36

Upper crustal emplacement and deformation of granitoids inside the Uppermost Unit of the Cretan nappe stack: constraints from U-Pb zircon dating, microfabrics and paleostress analyses

NASA Astrophysics Data System (ADS)

Kneuker, Tilo; Dörr, Wolfgang; Petschick, Rainer; Zulauf, Gernold

2015-03-01

The present study is dealing with the emplacement and deformation of diorite and quartz diorite exposed along new road cuts between Agios Nikolaos and Sitia (Uppermost Unit, eastern Crete). Mingling of both melt types is indicated by enclaves of diorite inside quartz diorite and vice versa. The diorite and quartz diorite intruded into coarse-grained white marble, which is in lateral contact to, but also forms the roof of, the intrusive body. Evidence for contact metamorphism is indicated by increasing grain size of calcite in the marble with decreasing distance from the diorite. U-Pb (TIMS) dating of zircons, separated from quartz diorite, yielded a concordant age at 74.0 ± 0.25 Ma, which is interpreted as emplacement age. As this age is close to published K-Ar cooling ages of hornblende and biotite, the melt should have intruded and cooled down rapidly at upper structural levels, which is not common for granitoids of the Uppermost Unit of Crete. Upper crustal melt emplacement is also documented by stoped blocks and by the lack of any ductile (viscous) deformation. The diorite and quartz diorite, however, are affected by strong post-Oligocene brittle faulting. Paleostress analysis, based on these faults, revealed a change in stress field from N-S and NNW-SSE shortening by thrusting (convergence between African and European plates) to NNE-SSW and NE-SW shortening accommodated by strike-slip (SW-ward extrusion of the Anatolian microplate). Calcite-twin density indicates high differential stress (260 ± 20 MPa) related to these phases of crustal shortening.

Formation of thick stratiform Fe-Ti oxide layers in layered intrusion and frequent replenishment of fractionated mafic magma: Evidence from the Panzhihua intrusion, SW China

NASA Astrophysics Data System (ADS)

Song, Xie-Yan; Qi, Hua-Wen; Hu, Rui-Zhong; Chen, Lie-Meng; Yu, Song-Yue; Zhang, Jia-Fei

2013-03-01

Panzhihua intrusion is one of the largest layered intrusions that hosts huge stratiform Fe-Ti oxide layers in the central part of the Emeishan large igneous province, SW China. Up to 60 m thick stratiform massive Fe-Ti oxide layers containing 85 modal% of magnetite and ilmenite and overlying magnetite gabbro compose cyclic units of the Lower Zone of the intrusion. The cyclic units of the Middle Zone consist of magnetite gabbro and overlying gabbro. In these cyclic units, contents of Fe2O3(t), TiO2 and Cr and Fe3+/Ti4+ ratio of the rocks decrease upward, Cr content of magnetite and forsterite percentage of olivine decrease as well. The Upper Zone consists of apatite gabbro characterized by enrichment of incompatible elements (e.g., 12-18 ppm La, 20-28 ppm Y) and increasing of Fe3+/Ti4+ ratio (from 1.3 to 2.3) upward. These features indicate that the Panzhihua intrusion was repeatedly recharged by more primitive magma and evolved magmas had been extracted. Calculations using MELTS indicate that extensive fractionation of olivine and clinopyroxene in deep level resulted in increasing Fe and Ti contents in the magma. When these Fe-Ti-enriched magmas were emplaced along the base of the Panzhihua intrusion, Fe-Ti oxides became an early crystallization phase, leading to a residual magma of lower density. We propose that the unusually thick stratiform Fe-Ti oxide layers resulted from coupling of gravity settling and sorting of the crystallized Fe-Ti oxides from Fe-Ti-enriched magmas and frequent magma replenishment along the floor of the magma chamber.

Pliocene to Recent Tectonic Activity of the Reşadiye Peninsula and the Relationship Between the Recent Earthquakes Occurred in the Gulf of Gökova: Preliminary Results.

NASA Astrophysics Data System (ADS)

Kahraman, Burcu; Özsayın, Erman; Üner, Serkan; Dirik, Kadir

2013-04-01

The E-W trending Reşadiye peninsula located at the southwestern part of the Anatolian Plate is an important horst developed between Gökova and Hisarönü Grabens. NW-trending the Datça Graben is the prominent structure comprising on the Reşadiye peninsula and records the significant fingerprints of palaeogeographical and kinematical characteristics from Pliocene to recent. The Datça Graben is controlled by NW-trending the Karaköy fault in the south and E-W trending the Kızlan fault in the north. Basement rocks of the graben are composed of ophiolitic rocks of the Lycian Nappes and Jurassic marine carbonates. The basinfill initiates with Early Pliocene Kızılaǧaç formation consisting conglomerates and continues with transgressive sequence (Yıldırımlı formation) composed of conglomerates, sandstones and marls with ignimbrite intercalations. Late Pliocene age was attributed to this formation based on the gastropoda and pelecypoda fauna according to previous studies. These units are unconformably overlain by Quaternary Karaköy formation consisting red blocky conglomerates. Pyroclastics of Quaternary age (161 ka) cover the older units. Alluvium, alluvial fan deposits and terrace deposits are the youngest units of the study area. To state the tectonic evolution of the Datça Graben, bedding planes and palaeostress analysis of the fault-slip data were used. The palaeostress analyses of the Kızlan fault clearly represent N-S tensional stress regime with pure normal fault characteristics. Due to the thick colluvium and alluvial fans, any fault-slip data were collected from the Karaköy fault. Considering the same stress regime is viable for the southwestern margin of the graben, fault planes ought to have normal fault characteristics with minor strike-slip component. SW-dipping bedding planes and SW-bearing palaeocurrent measurements show that Karaköy fault occurred before the Kızlan fault and the basin was first formed as a half-graben during Early Pliocene and continued till Late Pliocene. As the Kızlan fault juxtaposes the Kızılaǧaç and Yıldırımlı formations, Late Pliocene age is attributed to the fault. Focal mechanism solutions of recent earthquakes occurred in the Gökova Bay show N-S extension which is compatible with the palaeostress analyses of the Kızlan fault. This situation represents the ongoing activity along the northern margin of the Datça Graben.

75 FR 6702 - Notice of Realty Action: Recreation and Public Purposes Act Classification, California

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... provisions of the Recreation and Public Purposes Act (R&PP Act), as amended, approximately 133 acres of... Meridian T. 16 N., R. \\1/4\\ E., Sec. 1, portion of W\\1/2\\SE\\1/4\\; Sec. 12, portions of NW\\1/4\\NE\\1/4\\, E\\1/2\\NW\\1/4\\, E\\1/2\\SW\\1/ 4\\, and SW\\1/4\\SW\\1/4\\; Sec. 13, portions of W\\1/2\\NW\\1/4\\ and NW\\1/4\\SW\\1/4...

Assessment of policy and access to HIV prevention, care, and treatment services for men who have sex with men and for sex workers in Burkina Faso and Togo.

PubMed

Duvall, Sandra; Irani, Laili; Compaoré, Cyrille; Sanon, Patrice; Bassonon, Dieudonne; Anato, Simplice; Agounke, Jeannine; Hodo, Ama; Kugbe, Yves; Chaold, Gertrude; Nigobora, Berry; MacInnis, Ron

2015-03-01

In Burkina Faso and Togo, key populations of men who have sex with men (MSM) and sex workers (SW) have a disproportionately higher HIV prevalence. This study analyzed the 2 countries' policies impacting MSM and SW; to what extent the policies and programs have been implemented; and the role of the enabling environment, country leadership, and donor support. The Health Policy Project's Policy Assessment and Advocacy Decision Model methodology was used to analyze policy and program documents related to key populations, conduct key informant interviews, and hold stakeholder meetings to validate the findings. Several policy barriers restrict MSM/SW from accessing services. Laws criminalizing MSM/SW, particularly anti-solicitation laws, result in harassment and arrests of even nonsoliciting MSM/SW. Policy gaps exist, including few MSM/SW-supportive policies and HIV prevention measures, e.g., lubricant not included in the essential medicines list. The needs of key populations are generally not met due to policy gaps around MSM/SW participation in decision-making and funding allocation for MSM/SW-specific programming. Misaligned policies, eg, contradictory informed consent laws and protocols, and uneven policy implementation, such as stockouts of sexually transmitted infection kits, HIV testing materials, and antiretrovirals, undermine evidence-based policies. Even in the presence of a supportive donor and political community, public stigma and discrimination (S&D) create a hostile enabling environment. Policies are needed to address S&D, particularly health care provider and law enforcement training, and to authorize, fund, guide, and monitor services for key populations. MSM/SW participation and development of operational guidelines can improve policy implementation and service uptake.

Maximal oxygen uptake and cardiorespiratory response to maximal 400-m free swimming, running and cycling tests in competitive swimmers.

PubMed

Rodríguez, F A

2000-06-01

This study compared the cardiorespiratory response of trained swimmers to 400-m unimpeded front crawl swimming (SW), treadmill running (TR) and ergometer cycling (EC) maximal exercise tests, and evaluated the validity and specificity of a method to measure maximal aerobic power in swimming. Two series of experiments were conducted. In series A (n=15), comparisons were made between VO2peak and other cardiorespiratory variables in three maximal tests: after 400-m SW, and during incremental TR and EC. In series B, VO2 peak and related variables were measured after SW and during EC (n=33). No significant differences were observed between VO2peak and VE in the three modes of exercise, although SW values tended to be higher. After SW, maximal ventilatory response was characterized by higher tidal volumes (VT) and lower respiratory rates (fR) as compared with TR and EC. The highest heart rate values (fH) were also observed in TR, followed by EC and SW. In series B, no significant differences were observed either in peak VO2 or VE, but fH was also lower in SW. A maximal 400-m unimpeded freestyle SW test yields essentially equal or nonsignificantly higher peak VO2 and VE values than during maximal TR or EC tests in trained swimmers. The specific maximal cardiorespiratory response to the SW test is characterized by higher VT, lower fR, and lower fH. Breath-by-breath measurements during the immediate recovery after a 400-m voluntary maximal swim is proposed as a valid and specific test for directly measuring maximal metabolic parameters and evaluating specific maximal aerobic power in swimming.

Physiological preparedness and performance of Atlantic salmon Salmo salar smolts in relation to behavioural salinity preferences and thresholds.

PubMed

Stich, D S; Zydlewski, G B; Zydlewski, J D

2016-02-01

This study investigated the relationships between behavioural responses of Atlantic salmon Salmo salar smolts to saltwater (SW) exposure and physiological characteristics of smolts in laboratory experiments. It concurrently described the behaviour of acoustically tagged smolts with respect to SW and tidal cycles during estuary migration. Salmo salar smolts increased their use of SW relative to fresh water (FW) from April to June in laboratory experiments. Mean preference for SW never exceeded 50% of time in any group. Preference for SW increased throughout the course of smolt development. Maximum continuous time spent in SW was positively related to gill Na(+), K(+)-ATPase (NKA) activity and osmoregulatory performance in full-strength SW (measured as change in gill NKA activity and plasma osmolality). Smolts decreased depth upon reaching areas of the Penobscot Estuary where SW was present, and all fish became more surface oriented during passage from head of tide to the ocean. Acoustically tagged, migrating smolts with low gill NKA activity moved faster in FW reaches of the estuary than those with higher gill NKA activity. There was no difference in movement rate through SW reaches of the estuary based on gill NKA activity. Migrating fish moved with tidal flow during the passage of the lower estuary based on the observed patterns in both vertical and horizontal movements. The results indicate that smolts select low-salinity water during estuary migration and use tidal currents to minimize energetic investment in seaward migration. Seasonal changes in osmoregulatory ability highlight the importance of the timing of stocking and estuary arrival. © 2015 The Fisheries Society of the British Isles.

Heritability of seed weight in Maritime pine, a relevant trait in the transmission of environmental maternal effects

PubMed Central

Zas, R; Sampedro, L

2015-01-01

Quantitative seed provisioning is an important life-history trait with strong effects on offspring phenotype and fitness. As for any other trait, heritability estimates are vital for understanding its evolutionary dynamics. However, being a trait in between two generations, estimating additive genetic variation of seed provisioning requires complex quantitative genetic approaches for distinguishing between true genetic and environmental maternal effects. Here, using Maritime pine as a long-lived plant model, we quantified additive genetic variation of cone and seed weight (SW) mean and SW within-individual variation. We used a powerful approach combining both half-sib analysis and parent–offspring regression using several common garden tests established in contrasting environments to separate G, E and G × E effects. Both cone weight and SW mean showed significant genetic variation but were also influenced by the maternal environment. Most of the large variation in SW mean was attributable to additive genetic effects (h2=0.55–0.74). SW showed no apparent G × E interaction, particularly when accounting for cone weight covariation, suggesting that the maternal genotypes actively control the SW mean irrespective of the amount of resources allocated to cones. Within-individual variation in SW was low (12%) relative to between-individual variation (88%), and showed no genetic variation but was largely affected by the maternal environment, with greater variation in the less favourable sites for pine growth. In summary, results were very consistent between the parental and the offspring common garden tests, and clearly indicated heritable genetic variation for SW mean but not for within-individual variation in SW. PMID:25160045

Transcriptomic basis of functional difference and coordination between seeds and the silique wall of Brassica napus during the seed-filling stage.

PubMed

Liu, Han; Yang, Qingyong; Fan, Chuchuan; Zhao, Xiaoqin; Wang, Xuemin; Zhou, Yongming

2015-04-01

The silique of oilseed rape (Brassica napus) is a composite organ including seeds and the silique wall (SW) that possesses distinctly physiological, biochemical and functional differentiations. Yet, the molecular events controlling such differences between the SW and seeds, as well as their coordination during silique development at transcriptional level are largely unknown. Here, we identified large sets of differentially expressed genes in the SW and seeds of siliques at 21-22 days after flowering with a Brassica 95K EST microarray. At this particular stage, there were 3278 SW preferentially expressed genes and 2425 seed preferentially expressed genes. Using the MapMan visualization software, genes differentially regulated in various metabolic pathways and sub-pathways between the SW and seeds were revealed. Photosynthesis and transport-related genes were more actively transcripted in the SW, while those involved in lipid metabolism were more active in seeds during the seed filling stage. On the other hand, genes involved in secondary metabolisms were selectively regulated in the SW and seeds. Large numbers of transcription factors were identified to be differentially expressed between the SW and seeds, suggesting a complex pattern of transcriptional control in these two organs. Furthermore, most genes discussed in categories or pathways showed a similar expression pattern through 21 DAF to 42 DAF. Our results thus provide insights into the coordination of seeds and the SW in the developing silique at the transcriptional levels, which will facilitate the functional studies of important genes for improving B. napus seed productivity and quality. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures.

PubMed

Foglietta, Federica; Duchi, Serena; Canaparo, Roberto; Varchi, Greta; Lucarelli, Enrico; Dozza, Barbara; Serpe, Loredana

2017-03-15

Mesenchymal stem cells (MSC) possess the distinctive feature of homing in on and engrafting into the tumor stroma making their therapeutic applications in cancer treatment very promising. Research into new effectors and external stimuli, which can selectively trigger the release of cytotoxic species from MSC toward the cancer cells, significantly raises their potential. Shock waves (SW) have recently gained recognition for their ability to induce specific biological effects, such as the local generation of cytotoxic reactive oxygen species (ROS) in a non-invasive and tunable manner. We thus investigate whether MSC are able to generate ROS and, in turn, affect cancer cell growth when in co-culture with human glioblastoma (U87) or osteosarcoma (U2OS) cells and exposed to SW. MSC were found to be the cell line that was most sensitive to SW treatment as shown by SW-induced ROS production and cytotoxicity. Notably, U87 and U2OS cancer cell growth was unaffected by SW exposure. However, significant decreases in cancer cell growth, 1.8 fold for U87 and 2.3 fold for U2OS, were observed 24h after the SW treatment of MSC co-cultures with cancer cells. The ROS production induced in MSC by SW exposure was then responsible for lipid peroxidation and cell death in U87 and U2OS cells co-cultured with MSC. This experiment highlights the unique ability of MSC to generate ROS upon SW treatment and induce the cell death of co-cultured cancer cells. SW might therefore be proposed as an innovative tool for MSC-mediated cancer treatment. Copyright © 2017 Elsevier Inc. All rights reserved.

Shock Wave Injury to the Kidney in SWL: Review and Perspective

NASA Astrophysics Data System (ADS)

McAteer, James A.; Evan, Andrew P.; Willis, Lynn R.; Connors, Bret A.; Williams, James C.; Pishchalnikov, Yuri A.; Lingeman, James E.

2007-04-01

Shock wave lithotripsy (SWL) is a first-line option for treatment for urinary calculi—particularly effective for the removal of uncomplicated stones from the upper urinary tract. The success of lithotripsy is tempered, however, by the occurrence of acute injury that has been reported to progress to long-term complications. SW trauma to the kidney is a vascular lesion characterized by parenchymal and subcapsular bleeding. The acute lesion is dose-dependent, and typically localized to the focal volume of the lithotripter. Cavitation has been implicated in vessel rupture, but SW-shear has the potential to be a primary mechanism for damage as well. Possible chronic adverse effects of SWL may include new-onset hypertension, development of diabetes, and exacerbation of stone disease. If acute trauma could be reduced, it seems likely that serious long-term effects could be minimized, or even eliminated. Reducing the dose of SW's needed for stone breakage is one option. Improved coupling improves stone breakage, and slowing SW rate significantly improves stone-free outcomes. Experiments with animals now show that treatment protocols can be designed to protect against tissue injury. Initiating treatment with low energy SW's dramatically reduces lesion size, and reducing the rate of SW delivery virtually eliminates SW trauma altogether. SWL stands to gain from new advances in technology, as lithotripters become safer and more effective. Perhaps the greatest progress will be made when we have determined the physical mechanisms of SW action both for stone breakage and tissue damage, and have better characterized the biological response to SW's—as this will provide the principles needed to achieve the best combination of safety and efficiency with whatever lithotripter is at hand.

The osmoregulatory effects of rearing Mozambique tilapia in a tidally changing salinity.

PubMed

Moorman, Benjamin P; Inokuchi, Mayu; Yamaguchi, Yoko; Lerner, Darren T; Grau, E Gordon; Seale, Andre P

2014-10-01

The native distribution of Mozambique tilapia, Oreochromis mossambicus, is characterized by estuarine areas subject to salinity variations between fresh water (FW) and seawater (SW) with tidal frequency. Osmoregulation in the face of changing environmental salinity is largely mediated through the neuroendocrine system and involves the activation of ion uptake and extrusion mechanisms in osmoregulatory tissues. We compared plasma osmolality, plasma prolactin (PRL), pituitary PRL mRNA, and mRNA of branchial ion pumps, transporters, channels, and PRL receptors in tilapia reared in FW, SW, brackish water (BW) and in tidally-changing salinity, which varied between FW (TF) and SW (TS) every 6h. Plasma PRL was higher in FW tilapia than in SW, BW, TF, and TS tilapia. Unlike tilapia reared in FW or SW, fish in salinities that varied tidally showed no correlation between plasma osmolality and PRL. In FW fish, gene expression of PRL receptor 1 (PRLR1), Na(+)/Cl(-) cotransporter (NCC), aquaporin 3 (AQP3) and two isoforms of Na(+)/K(+)-ATPase (NKA α1a and NKA α1b) was higher than that of SW, BW or tidally-changing salinity fish. Gene expression of the Na(+)/K(+)/2Cl(-) cotransporter (NKCC1a), and the cystic fibrosis transmembrane conductance regulator (CFTR) were higher in fish in SW, BW or a tidally-changing salinity than in FW fish. Immunocytochemistry revealed that ionocytes of fish in tidally-changing salinities resemble ionocytes of SW fish. This study indicated that tilapia reared in a tidally-changing salinity can compensate for large changes in external osmolality while maintaining osmoregulatory parameters within a narrow range closer to that observed in SW-acclimated fish. Copyright © 2014 Elsevier Inc. All rights reserved.

Two different genotypes of H1N2 swine influenza virus isolated in northern China and their pathogenicity in animals.

PubMed

Yang, Huanliang; Chen, Yan; Qiao, Chuanling; Xu, Chuantian; Yan, Minghua; Xin, Xiaoguang; Bu, Zhigao; Chen, Hualan

2015-02-25

During 2006 and 2007, two swine-origin triple-reassortant influenza A (H1N2) viruses were isolated from pigs in northern China, and the antigenic characteristics of the hemagglutinin protein of the viruses were examined. Genotyping and phylogenetic analyses demonstrated different emergence patterns for the two H1N2 viruses, Sw/Hebei/10/06 and Sw/Tianjin/1/07. Sequences for the other genes encoding the internal proteins were compared with the existing data to determine their origins and establish the likely mechanisms of genetic reassortment. Sw/Hebei/10/06 is an Sw/Indiana/9K035/99-like virus, whereas Sw/Tianjin/1/07 represents a new H1N2 genotype with surface genes of classic swine and human origin and internal genes originating from the Eurasian avian-like swine H1N1 virus. Six-week-old female BALB/c mice infected with the Sw/HeB/10/06 and Sw/TJ/1/07 viruses showed an average weight loss of 12.8% and 8.1%, respectively. Healthy six-week-old pigs were inoculated intranasally with either the Sw/HeB/10/06 or Sw/TJ/1/07 virus. No considerable changes in the clinical presentation were observed post-inoculation in any of the virus-inoculated groups, and the viruses effectively replicated in the nasal cavity and lung tissue. Based on the results, it is possible that the new genotype of the swine H1N2 virus that emerged in China may become widespread in the swine population and pose a potential threat to public health. Copyright © 2014 Elsevier B.V. All rights reserved.

Enhancement of hypermutation frequency in the chicken B cell line DT40 for efficient diversification of the antibody repertoire

DOE Office of Scientific and Technical Information (OSTI.GOV)

Magari, Masaki; Kanehiro, Yuichi; Todo, Kagefumi

Chicken B cell line DT40 continuously accumulates mutations in the immunoglobulin variable region (IgV) gene by gene conversion and point mutation, both of which are mediated by activation-induced cytidine deaminase (AID), thereby producing an antibody (Ab) library that is useful for screening monoclonal Abs (mAbs) in vitro. We previously generated an engineered DT40 line named DT40-SW, whose AID expression can be reversibly switched on or off, and developed an in vitro Ab generation system using DT40-SW cells. To efficiently create an Ab library with sufficient diversity, higher hypermutation frequency is advantageous. To this end, we generated a novel cell linemore » DT40-SW{Delta}C, which conditionally expresses a C-terminus-truncated AID mutant lacking the nuclear export signal. The transcription level of the mutant AID gene in DT40-SW{Delta}C cells was similar to that of the wild-type gene in DT40-SW cells. However, the protein level of the truncated AID mutant was less than that of the wild type. The mutant protein was enriched in the nuclei of DT40-SW{Delta}C cells, although the protein might be highly susceptible to degradation. In DT40-SW{Delta}C cells, both gene conversion and point mutation occurred in the IgV gene with over threefold higher frequency than in DT40-SW cells, suggesting that a lower level of the mutant AID protein was sufficient to increase mutation frequency. Thus, DT40-SW{Delta}C cells may be useful for constructing Ab libraries for efficient screening of mAbs in vitro.« less

Integration of seismic interpretation and well logging analysis of Abu Roash D Member, Gindi Basin, Egypt: Implication for detecting and evaluating fractured carbonate reservoirs

NASA Astrophysics Data System (ADS)

Sarhan, Mohammad Abdelfattah; Basal, A. M. K.; Ibrahim, Ibrahim Mohamed

2017-11-01

Based on seismic interpretation, the time structure map on top of the Abu Roash D Member in the area of study within the Gindi Basin displays an NE-SW anticline plunging toward the NE intersected by two NE-SW reverse faults. This faulted anticline has been interpreted to have formed by the Late Cretaceous tectonic inversion resulting from the NW movement of the African Plate relative to Laurasia. This anticline creates a distinctive closure which may represent a possible structural hydrocarbon trap in the fractured limestone of the Abu Roash D Member in this area. Through well-logging analysis, the variable cementation exponent ;m; has been calculated using the Pickett Plot for the available wells in order to examine the presence of fractures within the entire carbonate Abu Roash D Member. The calculated ;m; for Abu Roash D in the two studied wells are 1.56 and 1.34 for SWQ-21 and SWQ-25; respectively which is indicative of the fractured limestone nature. The application of the correct ;m; (1.56) instead of 2 (traditional for the intergranular carbonate) for SWQ-21 well has revealed that, the water saturation for the uppermost part of Abu Roash D Member is lower than 50% (normal cut off for carbonate) possessing high porosity and reflecting good reservoir quality. The cross-plot between Archie water saturation (Sw) and neutron porosity (ΦN) for the uppermost part of this Member follows hyperbola with low BVW (Φ*Sw) value (0.06) which means that the reservoir is at irreducible state. The visual inspection for the log curve shapes in addition to the application of the presented technique in SWQ-25 well shows that the entire carbonate of Abu Roash D Member is water producing (Sw>50%). These results indicate that the upperpost part of the Abu Roash D Member in well SWQ-21 is fractured limestone and highly promising for hydrocarbon exploration within the Gindi Basin.

SU-G-JeP1-15: Sliding Window Prior Data Assisted Compressed Sensing for MRI Lung Tumor Tracking

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yip, E; Wachowicz, K; Rathee, S

Purpose: Prior Data Assisted Compressed Sensing (PDACS) is a partial k-space acquisition and reconstruction method for mobile tumour (i.e. lung) tracking using on-line MRI in radiotherapy. PDACS partially relies on prior data acquired at the beginning of dynamic scans, and is therefore susceptible to artifacts in longer duration scan due to slow drifts in MR signal. A novel sliding window strategy is presented to mitigate this effect. Methods: MRI acceleration is simulated by retrospective removal of data from the fully sampled sets. Six lung cancer patients were scanned (clinical 3T MRI) using a balanced steady state free precession (bSSFP) sequencemore » for 3 minutes at approximately 4 frames per second, for a total of 650 dynamics. PDACS acceleration is achieved by undersampling of k-space in a single pseudo-random pattern. Reconstruction iteratively minimizes the total variations while constraining the images to satisfy both the currently acquired data and the prior data in missing k-space. Our novel sliding window technique (SW-PDACS), uses a series of distinct pseudo-random under-sampling patterns of partial k-space – with the prior data drawn from a sliding window of the most recent data available. Under-sampled data, simulating 2 – 5x acceleration are reconstructed using PDACS and SW-PDACS. Three quantitative metrics: artifact power, centroid error and Dice’s coefficient are computed for comparison. Results: Quantitively metric values from all 6 patients are averaged in 3 bins, each containing approximately one minute of dynamic data. For the first minute bin, PDACS and SW-PDACS give comparable results. Progressive decline in image quality metrics in bins 2 and 3 are observed for PDACS. No decline in image quality is observed for SW-PDACS. Conclusion: The novel approach presented (SW-PDACS) is a more robust for accelerating longer duration (>1 minute) dynamic MRI scans for tracking lung tumour motion using on-line MRI in radiotherapy. B.G. Fallone is a co-founder and CEO of MagnetTx Oncology Solutions (under discussions to license Alberta bi-planar linac MR for commercialization).« less

The Antioxidant Peroxiredoxin 6 (Prdx6) Exhibits Different Profiles in the Livers of Seawater- and Fresh Water-Acclimated Milkfish, Chanos chanos, upon Hypothermal Challenge

PubMed Central

Chang, Chia-Hao; Lo, Wan-Yu; Lee, Tsung-Han

2016-01-01

A tropical species, the euryhaline milkfish (Chanos chanos), is a crucial economic species in Southeast Asia and is intolerant of water temperature below 12°C. Large numbers of milkfish die during cold periods in winter. Hypothermal environments usually increase oxidative stress in teleosts, and the liver is the major organ for anti-oxidative responses in the body. Peroxiredoxin-6 (Prdx6) in mammals is a multi-functional enzyme and acts as both glutathione peroxidase, phospholipase A2 and acyl-transferase for maintenance of redox status and prevention of cell membrane peroxidation. Prdx6 can protect cells from oxidant-induced membrane damage by translocating the Prdx6 protein from the cytosol to the membrane. Upon cold stress, Ccprdx6 transcript levels were up-regulated after 24 h and 96 h in livers of fresh water (FW)- and seawater (SW)-acclimated milkfish, respectively. In the hypothermal FW group, the Prdx6 protein was up-regulated in the cytosol of hepatocytes with a similar role as glutathione peroxidase to reduce oxidative stress upon hypothermal challenge. Conversely, in hypothermal SW milkfish, total Prdx6 protein was down-regulated. However, cytosolic Prdx6 protein was translocated to the membrane, using the ability of phospholipase A2 to stabilize the membrane redox state. Moreover, H2O2 content was increased in FW-acclimated milkfish livers upon hypothermal challenge. Ex vivo H2O2 treatment of milkfish livers also induced Ccprdx6 transcriptional expression, which provided more evidence of the antioxidant role of milkfish Prdx6. Taken together, upon hypothermal challenge, greater oxidative stress in livers of FW-acclimated milkfish rather than SW-acclimated individuals led to different profiles of hepatic CcPrdx6 expression between the FW and SW group. The results indicated that CcPrdx6 played the role of antioxidant with different mechanisms, i.e., binding to reactive oxygen species and stabilizing membrane fluidity, in livers of hypothermal FW and SW milkfish, respectively. PMID:27965586

The Antioxidant Peroxiredoxin 6 (Prdx6) Exhibits Different Profiles in the Livers of Seawater- and Fresh Water-Acclimated Milkfish, Chanos chanos, upon Hypothermal Challenge.

PubMed

Chang, Chia-Hao; Lo, Wan-Yu; Lee, Tsung-Han

2016-01-01

A tropical species, the euryhaline milkfish ( Chanos chanos ), is a crucial economic species in Southeast Asia and is intolerant of water temperature below 12°C. Large numbers of milkfish die during cold periods in winter. Hypothermal environments usually increase oxidative stress in teleosts, and the liver is the major organ for anti-oxidative responses in the body. Peroxiredoxin-6 (Prdx6) in mammals is a multi-functional enzyme and acts as both glutathione peroxidase, phospholipase A 2 and acyl-transferase for maintenance of redox status and prevention of cell membrane peroxidation. Prdx6 can protect cells from oxidant-induced membrane damage by translocating the Prdx6 protein from the cytosol to the membrane. Upon cold stress, Ccprdx6 transcript levels were up-regulated after 24 h and 96 h in livers of fresh water (FW)- and seawater (SW)-acclimated milkfish, respectively. In the hypothermal FW group, the Prdx6 protein was up-regulated in the cytosol of hepatocytes with a similar role as glutathione peroxidase to reduce oxidative stress upon hypothermal challenge. Conversely, in hypothermal SW milkfish, total Prdx6 protein was down-regulated. However, cytosolic Prdx6 protein was translocated to the membrane, using the ability of phospholipase A 2 to stabilize the membrane redox state. Moreover, H 2 O 2 content was increased in FW-acclimated milkfish livers upon hypothermal challenge. Ex vivo H 2 O 2 treatment of milkfish livers also induced Ccprdx6 transcriptional expression, which provided more evidence of the antioxidant role of milkfish Prdx6. Taken together, upon hypothermal challenge, greater oxidative stress in livers of FW-acclimated milkfish rather than SW-acclimated individuals led to different profiles of hepatic CcPrdx6 expression between the FW and SW group. The results indicated that CcPrdx6 played the role of antioxidant with different mechanisms, i.e., binding to reactive oxygen species and stabilizing membrane fluidity, in livers of hypothermal FW and SW milkfish, respectively.

TRANSPORT OF SOLAR WIND H{sup +} AND He{sup ++} IONS ACROSS EARTH’S BOW SHOCK

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parks, G. K.; Lin, N.; Lee, E.

2016-07-10

We have investigated the dependence of mass, energy, and charge of solar wind (SW) transport across Earth’s bow shock. An examination of 111 crossings during quiet SW in both quasi-perpendicular and quasi-parallel shock regions shows that 64 crossings had various degrees of heating and thermalization of SW. We found 22 crossings where the SW speed was <400 km s{sup −1}. The shock potential of a typical supercritical quasi-perpendicular shock estimated from deceleration of the SW and cutoff energy of electron flat top distribution is ∼50 Volts. We find that the temperatures of H{sup +} and He{sup ++} beams that penetratemore » the shock can sometimes be nearly the same in the upstream and downstream regions, indicating little or no heating had occurred crossing the bow shock. None of the models predict that the SW can cross the bow shock without heating. Our observations are important constraints for new models of collisionless shocks.« less

On the Accretion Rates of SW Sextantis Nova-like Variables

NASA Astrophysics Data System (ADS)

Ballouz, Ronald-Louis; Sion, Edward M.

2009-06-01

We present accretion rates for selected samples of nova-like variables having IUE archival spectra and distances uniformly determined using an infrared method by Knigge. A comparison with accretion rates derived independently with a multiparametric optimization modeling approach by Puebla et al. is carried out. The accretion rates of SW Sextantis nova-like systems are compared with the accretion rates of non-SW Sextantis systems in the Puebla et al. sample and in our sample, which was selected in the orbital period range of three to four and a half hours, with all systems having distances using the method of Knigge. Based upon the two independent modeling approaches, we find no significant difference between the accretion rates of SW Sextantis systems and non-SW Sextantis nova-like systems insofar as optically thick disk models are appropriate. We find little evidence to suggest that the SW Sex stars have higher accretion rates than other nova-like cataclysmic variables (CVs) above the period gap within the same range of orbital periods.

Global migration of influenza A viruses in swine

PubMed Central

Nelson, Martha I.; Viboud, Cécile; Vincent, Amy L.; Culhane, Marie R.; Detmer, Susan E.; Wentworth, David E.; Rambaut, Andrew; Suchard, Marc A.; Holmes, Edward C.; Lemey, Philippe

2015-01-01

The complex and unresolved evolutionary origins of the 2009 H1N1 influenza pandemic exposed major gaps in our knowledge of the global spatial ecology and evolution of influenza A viruses in swine (swIAVs). Here we undertake an expansive phylogenetic analysis of swIAV sequence data and demonstrate that the global live swine trade strongly predicts the spatial dissemination of swIAVs, with Europe and North America acting as sources of viruses in Asian countries. In contrast, China has the world’s largest swine population but is not a major exporter of live swine, and is not an important source of swIAVs in neighboring Asian countries or globally. A meta-population simulation model incorporating trade data predicts that the global ecology of swIAVs is more complex than previously thought, and the US and China’s large swine populations are unlikely to be representative of swIAV diversity in their respective geographic regions, requiring independent surveillance efforts throughout Latin America and Asia. PMID:25813399

Endocrine systems in juvenile anadromous and landlocked Atlantic salmon (Salmo salar): Seasonal development and seawater acclimation

USGS Publications Warehouse

Nilsen, Tom O.; Ebbesson, Lars O.E.; Kiilerich, P.; Bjornsson, B. Th; Madsen, Steffen S.; McCormick, S.D.; Stefansson, S.O.

2008-01-01

The present study compares developmental changes in plasma levels of growth hormone (GH), insulin-like growth factor I (IGF-I) and cortisol, and mRNA levels of their receptors and the prolactin receptor (PRLR) in the gill of anadromous and landlocked Atlantic salmon during the spring parr-smolt transformation (smoltification) period and following four days and one month seawater (SW) acclimation. Plasma GH and gill GH receptor (GHR) mRNA levels increased continuously during the spring smoltification period in the anadromous, but not in landlocked salmon. There were no differences in plasma IGF-I levels between strains, or any increase during smoltification. Gill IGF-I and IGF-I receptor (IGF-IR) mRNA levels increased in anadromous salmon during smoltification, with no changes observed in landlocked fish. Gill PRLR mRNA levels remained stable in both strains during spring. Plasma cortisol levels in anadromous salmon increased 5-fold in May and June, but not in landlocked salmon. Gill glucocorticoid receptor (GR) mRNA levels were elevated in both strains at the time of peak smoltification in anadromous salmon, while mineralocorticoid receptor (MR) mRNA levels remained stable. Only anadromous salmon showed an increase of gill 11??-hydroxysteroid dehydrogenase type-2 (11??-HSD2) mRNA levels in May. GH and gill GHR mRNA levels increased in both strains following four days of SW exposure in mid-May, whereas only the anadromous salmon displayed elevated plasma GH and GHR mRNA after one month in SW. Plasma IGF-I increased after four days in SW in both strains, decreasing in both strains after one month in SW. Gill IGF-I mRNA levels were only increased in landlocked salmon after 4 days in SW. Gill IGF-IR mRNA levels in SW did not differ from FW levels in either strain. Gill PRLR mRNA did not change after four days of SW exposure, and decreased in both strains after one month in SW. Plasma cortisol levels did not change following SW exposure in either strain. Gill GR, 11??-HSD2 and MR mRNA levels increased after four days in SW in both strains, whereas only the anadromous strain maintained elevated gill GR and 11??-HSD2 mRNA levels after one month in SW. The results indicate that hormones and receptors of the GH and cortisol axes are present at significantly lower levels during spring development and SW acclimation in landlocked relative to anadromous salmon. These findings suggest that attenuation of GH and cortisol axes may, at least partially, result in reduced preparatory upregulation of key gill ion-secretory proteins, possibly a result of reduced selection pressure for marine adaptations in landlocked salmon. ?? 2007 Elsevier Inc. All rights reserved.

Solar energetic particle events in different types of solar wind

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kahler, S. W.; Vourlidas, A., E-mail: stephen.kahler@kirtland.af.mil

2014-08-10

We examine statistically some properties of 96 20 MeV gradual solar energetic proton (SEP) events as a function of three different types of solar wind (SW) as classified by Richardson and Cane. Gradual SEP (E > 10 MeV) events are produced in shocks driven by fast (V ≳ 900 km s{sup –1}) and wide (W > 60°) coronal mass ejections (CMEs). We find no differences among the transient, fast, and slow SW streams for SEP 20 MeV proton event timescales. It has recently been found that the peak intensities Ip of these SEP events scale with the ∼2 MeV protonmore » background intensities, which may be a proxy for the near-Sun shock seed particles. Both the intensities Ip and their 2 MeV backgrounds are significantly enhanced in transient SW compared to those of fast and slow SW streams, and the values of Ip normalized to the 2 MeV backgrounds only weakly correlate with CME V for all SW types. This result implies that forecasts of SEP events could be improved by monitoring both the Sun and the local SW stream properties and that the well known power-law size distributions of Ip may differ between transient and long-lived SW streams. We interpret an observed correlation between CME V and the 2 MeV background for SEP events in transient SW as a manifestation of enhanced solar activity.« less

Two-Dimensional Standing Wave Total Internal Reflection Fluorescence Microscopy: Superresolution Imaging of Single Molecular and Biological Specimens

PubMed Central

Chung, Euiheon; Kim, Daekeun; Cui, Yan; Kim, Yang-Hyo; So, Peter T. C.

2007-01-01

The development of high resolution, high speed imaging techniques allows the study of dynamical processes in biological systems. Lateral resolution improvement of up to a factor of 2 has been achieved using structured illumination. In a total internal reflection fluorescence microscope, an evanescence excitation field is formed as light is total internally reflected at an interface between a high and a low index medium. The <100 nm penetration depth of evanescence field ensures a thin excitation region resulting in low background fluorescence. We present even higher resolution wide-field biological imaging by use of standing wave total internal reflection fluorescence (SW-TIRF). Evanescent standing wave (SW) illumination is used to generate a sinusoidal high spatial frequency fringe pattern on specimen for lateral resolution enhancement. To prevent thermal drift of the SW, novel detection and estimation of the SW phase with real-time feedback control is devised for the stabilization and control of the fringe phase. SW-TIRF is a wide-field superresolution technique with resolution better than a fifth of emission wavelength or ∼100 nm lateral resolution. We demonstrate the performance of the SW-TIRF microscopy using one- and two-directional SW illumination with a biological sample of cellular actin cytoskeleton of mouse fibroblast cells as well as single semiconductor nanocrystal molecules. The results confirm the superior resolution of SW-TIRF in addition to the merit of a high signal/background ratio from TIRF microscopy. PMID:17483188

Convergent Evolution of the Osmoregulation System in Decapod Shrimps.

PubMed

Yuan, Jianbo; Zhang, Xiaojun; Liu, Chengzhang; Duan, Hu; Li, Fuhua; Xiang, Jianhai

2017-02-01

In adaptating to different aquatic environments, seawater (SW) and freshwater (FW) shrimps have exploited different adaptation strategies, which should generate clusters of genes with different adaptive features. However, little is known about the genetic basis of these physiological adaptations. Thus, in this study, we performed comparative transcriptomics and adaptive evolution analyses on SW and FW shrimps and found that convergent evolution may have happened on osmoregulation system of shrimps. We identified 275 and 234 positively selected genes in SW and FW shrimps, respectively, which enriched in the functions of ion-binding and membrane-bounded organelles. Among them, five (CaCC, BEST2, GPDH, NKA, and Integrin) and four (RasGAP, RhoGDI, CNK3, and ODC) osmoregulation-related genes were detected in SW and FW shrimps, respectively. All five genes in SW shrimps have been reported to have positive effects on ion transportation, whereas RasGAP and RhoGDI in FW shrimps are associated with negative control of ion transportation, and CNK3 and ODC play central roles in cation homeostasis. Besides, the phylogenetic tree reconstructed from the positively selected sites separated the SW and FW shrimps into two groups. Distinct subsets of parallel substitutions also have been found in these osmoregulation-related genes in SW and FW shrimps. Therefore, our results suggest that distinct convergent evolution may have occurred in the osmoregulation systems of SW and FW shrimps. Furthermore, positive selection of osmoregulation-related genes may be beneficial for the regulation of water and salt balance in decapod shrimps.

76 FR 64990 - Audit and Financial Management Advisory (AFMAC)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-19

... Street, SW., Office of the Chief Financial Officer, Washington, DC 20416. SUPPLEMENTARY INFORMATION..., in order to be placed on the agenda. Jonathan Carver, Chief Financial Officer, 409 3rd Street, SW... Chief Financial Officer, 409 3rd Street, SW., Washington, DC 20416. For more information, please visit...

Validating a Steiner-Waldorf Teacher Education Programme

ERIC Educational Resources Information Center

Oberski, Iddo; Pugh, Alistair; MacLean, Astrid; Cope, Peter

2007-01-01

Steiner-Waldorf (SW) education, based on the work of Rudolf Steiner (1861-1925), provides a distinctive form of education. There are approximately 900 SW schools worldwide. The only teacher training course for SW education in Scotland is currently offered at the Edinburgh Rudolf Steiner School (ERSS). Although students are continuously assessed on…

78 FR 8992 - Energy Conservation Program: Test Procedures for Residential Clothes Dryers

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-07

... Energy, Building Technologies Program, Mailstop EE-2J, 1000 Independence Avenue SW., Washington, DC 20585... Technologies Program, 6th Floor, 950 L'Enfant Plaza SW., Washington, DC 20024. Telephone: (202) 586-2945. If... and Renewable Energy, Building Technologies Program, EE-2J, 1000 Independence Avenue SW., Washington...

AGEs and HMGB1 Increase Inflammatory Cytokine Production from Human Placental Cells, Resulting in an Enhancement of Monocyte Migration.

PubMed

Shirasuna, Koumei; Seno, Kotomi; Ohtsu, Ayaka; Shiratsuki, Shogo; Ohkuchi, Akihide; Suzuki, Hirotada; Matsubara, Shigeki; Nagayama, Shiho; Iwata, Hisataka; Kuwayama, Takehito

2016-05-01

Advanced glycation end products (AGEs) and high-mobility group box-1 (HMGB1) are considered contributing to placental inflammation. We examined the effect of AGEs and HMGB1 on cytokines from Sw.71 human trophoblast cell lines and the interactions between Sw.71 cells and THP-1-monocytes. Sw.71 cells were cultured with/without AGEs or HMGB1. We examined the role of AGEs or HMGB1 on THP1 migration and effect of AGEs on IL-6 from Sw.71 cells using co-cultures or conditioned medium from THP-1 cells. AGEs and HMGB1 increased interleukin (IL)-6, IL-8, and chemokine C-C motif ligand 2 (CCL2) secretion from Sw.71 cells. The secretion of IL-6 was dependent on reactive oxygen species (ROS) and NF-κB. AGEs stimulated IL-6 secretion through receptor RAGE and TLR4, whereas HMGB1 stimulated it through TLR4. AGEs, but not HMGB1, increased monocyte migration via IL-8 and CCL2 from Sw.71 cells. THP-1 monocytes induced IL-6 secretion from Sw.71 cells, and AGEs further stimulated it. AGEs and HMGB1 may promote sterile placental inflammation cooperating with monocytes/macrophages. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Shock wave-induced brain injury in rat: novel traumatic brain injury animal model.

PubMed

Nakagawa, Atsuhiro; Fujimura, Miki; Kato, Kaoruko; Okuyama, Hironobu; Hashimoto, Tokitada; Takayama, Kazuyoshi; Tominaga, Teiji

2008-01-01

In blast wave injury and high-energy traumatic brain injury, shock waves (SW) play an important role along with cavitation phenomena. However, due to lack of reliable and reproducible technical approaches, extensive study of this type of injury has not yet been reported. The present study aims to develop reliable SW-induced brain injury model by focusing micro-explosion generated SW in the rat brain. Adult male rats were exposed to single SW focusing created by detonation of microgram order of silver azide crystals with laser irradiation at a focal point of a truncated ellipsoidal cavity of20 mm minor diameter and the major to minor diameter ratio of 1.41 after craniotomy. The pressure profile was recorded using polyvinylidene fluoride needle hydrophone. Animals were divided into three groups according to the given overpressure: Group I: Control, Group II: 12.5 +/- 2.5 MPa (high pressure), and Group III: 1.0 +/- 0.2 MPa (low pressure). Histological changes were evaluated over time by hematoxylin-eosin staining. Group II SW injuries resulted in contusional hemorrhage in reproducible manner. Group III exposure resulted in spindle-shaped changes of neurons and elongation of nucleus without marked neuronal injury. The use of SW loading by micro-explosion is useful to provide a reliable and reproducible SW-induced brain injury model in rats.

Spatiotemporal Dynamics of Surface Water Extent from Three Decades of Seasonally Continuous Landsat Time Series at Subcontinental Scale

NASA Astrophysics Data System (ADS)

Tulbure, M. G.; Broich, M.

2015-12-01

Surface water is a critical resource in semi-arid areas. The Murray-Darling Basin (MDB) of Australia, one of the largest semi-arid basins in the world is aiming to set a worldwide example of how to balance multiple interests (i.e. environment, agriculture and urban use), but has suffered significant water shrinkages during the Millennium Drought (1999-2009), followed by extensive flooding. Baseline information and systematic quantification of surface water (SW) extent and flooding dynamics in space and time are needed for managing SW resources across the basin but are currently lacking. To synoptically quantify changes in SW extent and flooding dynamics over MDB, we used seasonally continuous Landsat TM and ETM+ data (1986 - 2011) and generic machine learning algorithms. We further mapped flooded forest at a riparian forest site that experienced severe tree dieback due to changes in flooding regime. We used a stratified sampling design to assess the accuracy of the SW product across time. Accuracy assessment yielded an overall classification accuracy of 99.94%, with producer's and user's accuracy of SW of 85.4% and 97.3%, respectively. Overall accuracy was the same for Landsat 5 and 7 data but user's and producer's accuracy of water were higher for Landsat 7 than 5 data and stable over time. Our validated results document a rapid loss in SW bodies. The number, size, and total area of SW showed high seasonal variability with highest numbers in winter and lowest numbers in summer. SW extent per season per year showed high interannual and seasonal variability, with low seasonal variability during the Millennium Drought. Examples of current uses of the new dataset will be presented and include (1) assessing ecosystem response to flooding with implications for environmental water releases, one of the largest investment in environment in Australia; (2) quantifying drivers of SW dynamics (e.g. climate, human activity); (3) quantifying changes in SW dynamics and connectivity for water dependent organisms; (4) assessing the impact of flooding on riparian vegetation health. The approach developed here is globally applicable, relevant to areas with competing water demands (e.g. Okavango delta, Mekong Basin). Future work should incorporate Landsat 8 and Sentinel-2 data for continued quantification of SW dynamics.

Spatiotemporal Dynamics of Surface Water Extent from Three Decades of Seasonally Continuous Landsat Time Series at Subcontinental Scale

NASA Astrophysics Data System (ADS)

Tulbure, M. G.; Broich, M.; Stehman, Stephen V.

2016-06-01

Surface water is a critical resource in semi-arid areas. The Murray-Darling Basin (MDB) of Australia, one of the largest semi-arid basins in the world is aiming to set a worldwide example of how to balance multiple interests (i.e. environment, agriculture and urban use), but has suffered significant water shrinkages during the Millennium Drought (1999-2009), followed by extensive flooding. Baseline information and systematic quantification of surface water (SW) extent and flooding dynamics in space and time are needed for managing SW resources across the basin but are currently lacking. To synoptically quantify changes in SW extent and flooding dynamics over MDB, we used seasonally continuous Landsat TM and ETM+ data (1986 - 2011) and generic machine learning algorithms. We further mapped flooded forest at a riparian forest site that experienced severe tree dieback due to changes in flooding regime. We used a stratified sampling design to assess the accuracy of the SW product across time. Accuracy assessment yielded an overall classification accuracy of 99.94%, with producer's and user's accuracy of SW of 85.4% and 97.3%, respectively. Overall accuracy was the same for Landsat 5 and 7 data but user's and producer's accuracy of water were higher for Landsat 7 than 5 data and stable over time. Our validated results document a rapid loss in SW bodies. The number, size, and total area of SW showed high seasonal variability with highest numbers in winter and lowest numbers in summer. SW extent per season per year showed high interannual and seasonal variability, with low seasonal variability during the Millennium Drought. Examples of current uses of the new dataset will be presented and include (1) assessing ecosystem response to flooding with implications for environmental water releases, one of the largest investment in environment in Australia; (2) quantifying drivers of SW dynamics (e.g. climate, human activity); (3) quantifying changes in SW dynamics and connectivity for water dependent organisms; (4) assessing the impact of flooding on riparian vegetation health. The approach developed here is globally applicable, relevant to areas with competing water demands (e.g. Okavango River delta, Mekong River Basin). Future work should incorporate Landsat 8 and Sentinel-2 data for continued quantification of SW dynamics.

[The level of superoxide dismutase expression in primary and metastatic colorectal cancer cells in hypoxia and tissue normoxia].

PubMed

Skrzycki, Michał; Czeczot, Hanna; Chrzanowska, Alicja; Otto-Ślusarczyk, Dagmara

2015-11-01

Superoxide oxidase (SOD) is a key antioxidant enzyme protecting cells against oxidative stress, which might induce cancerogenesis. In tumor cells SOD influences the level of the reactive oxygen species (ROS) allowing for survival and proliferation. High rate of cells proliferation in tumor leads to their temporary hypoxia due to lower rate of angiogenesis. Therefore during tumor development, cancer cells function in conditions of hypoxia or tissue normoxia. The aim of study was to evaluate of SOD isoenzymes (SOD1 and SOD2) expression level in cell lines of primary (SW 480) and metastatic (SW 620) colorectal cancer, cultured in hypoxia (1% oxygen), tissue normoxia (10% oxygen), and atmospheric normoxia (21% oxygen). Cells were cultured in MEM medium in different oxygen concentrations (1%, 10%, 21%) in hypoxic chamber with oxygenation regulator. The number of living cells in lines SW 480 and 620 was determined by trypan blue method. Expression of SOD1 and SOD2 at the mRNA level was determined by RT-PCR and PCR. In both studied cell lines (SW 480 and SW 620), the number of living cells (viability) was increased in hypoxia and atmospheric normoxia. The expression level of SOD1 and SOD2 in studied cell lines was different. The lowest level of expression of both SOD isoenzymes was observed in hypoxia. In conditions of atmospheric normoxia the expression level of SOD1 in SW480 cell line was increased, and similar in SW620 cell line comparing to tissue normoxia. Whereas the SOD2 expression level in atmospheric normoxia conditions in both cell lines was significantly increased. Observed differences were statistically significant (p ≤ 0,05). The profile of expression of SOD1 and SOD2 in cell lines SW480 and SW620 indicates differentiated response of tumor cells depending on access to oxygen. Low level of SOD isoenzymes expression in SW480 and SW620 cells in hypoxia indicates decreased production of ROS. Differences of SOD isoenzymes expression level in tissue normoxia indicate their compensatory action, allowing to maintain the balance between O₂- removal and H₂O₂production in studied tumor cells. In atmospheric normoxia conditions increased expression level of SOD1 and SOD2 observed in studied cell lines points to oxidative stress. © 2015 MEDPRESS.

Spatiotemporal Dynamics and Trends in Surface Water and Flooding Extent from Three Decades of Seasonally Continuous Landsat Time Series at Subcontinental Scale: Product Development and Applications

NASA Astrophysics Data System (ADS)

Tulbure, M. G.; Broich, M.; Stehman, S. V.; Shendryk, I.; Heimhuber, V.; Kommareddy, A.; Bishop-Taylor, R.

2016-12-01

Surface water is a critical resource in semi-arid areas. The Murray-Darling Basin (MDB) of Australia, one of the largest semi-arid basins in the world is aiming to set a worldwide example of how to balance multiple interests (i.e. environment, agriculture and urban use), but has suffered significant water shrinkages during the Millennium Drought (1999-2009), followed by extensive flooding. Baseline information and systematic quantification of surface water (SW) extent and flooding dynamics in space and time are needed for managing SW resources across the basin but are currently lacking. To synoptically quantify changes in SW extent and flooding dynamics over MDB, we used seasonally continuous Landsat TM and ETM+ data (1986 - 2011) and generic machine learning algorithms. We further mapped flooded forest at a riparian forest site that experienced severe tree dieback due to changes in flooding regime. We used a stratified sampling design to assess the accuracy of the SW product across time. Accuracy assessment yielded an overall classification accuracy of 99.94%, with producer's and user's accuracy of SW of 85.4% and 97.3%, respectively. Overall accuracy was the same for Landsat 5 and 7 data but user's and producer's accuracy of water were higher for Landsat 7 than 5 data and stable over time. Our validated results document a rapid loss in SW bodies. The number, size, and total area of SW showed high seasonal variability with highest numbers in winter and lowest numbers in summer. SW extent per season per year showed high interannual and seasonal variability, with low seasonal variability during the Millennium Drought. Examples of current uses of the new dataset will be presented and include (1) assessing ecosystem response to flooding with implications for environmental water releases, one of the largest investment in environment in Australia; (2) quantifying drivers of SW dynamics (e.g. climate, human activity); (3) quantifying changes in SW dynamics and connectivity for water dependent organisms; (4) assessing the impact of flooding on riparian vegetation health. The approach developed here is globally applicable, relevant to areas with competing water demands (e.g. Okavango River delta, Mekong River Basin). Future work should incorporate Landsat 8 and Sentinel-2 data for continued quantification of SW dynamics.

76 FR 298 - Revisions to the California State Implementation Plan, San Joaquin Valley Air Pollution Control...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-04

...-water separators by requiring covers and use of vapor loss control devices. The rule is renumbered and...://www.epa.gov/ttn/oarpg/t1/memoranda/ractqanda.pdf . 6. ``Clean Water Act Analytical Methods'', U.S. EPA.../sw846/online/index.htm . 8. ``Control of Refinery Vacuum Producing Systems, Water Separators and Process...

A Theory of Electromagnetic Shielding with Applications to MIL-STD-285, IEEE-299, and EMP Simulation

DTIC Science & Technology

1985-02-01

in a building sized enclosure slot-like discontinuities may not all be small compar- ed to all wavelengths in the incident field, and slot resonan ...OFFICE OF RESEARCH/ NPP US AIR FORCE SPACE COMMAND ATTN STATE & LOCAL PROG SUPPORT O ATTN KKO 500 C STREET, SW ATTN KRQ WASHINGTON, DC 20472 ATTN XPOW

76 FR 26655 - Public Meetings on the Proposed Rule for Mandatory Inspection of Catfish and Catfish Products

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... photo ID to enter the building. The Jefferson Auditorium is located at Wing 6 in the South Building. Attendees should enter the building via Wing 5 or 7 on 14th Street and Independence Avenue, SW. The second... at the Delta Research and Extension Center of the Mississippi State University. The Charles Capp...

75 FR 64984 - Availability of an Environmental Assessment for a Biological Control Agent for Hawkweeds

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-21

..., Riverdale, MD 20737-1238. Please state that your comment refers to Docket No. APHIS-2010-0078. Reading Room: You may read any comments that we receive on the environmental assessment in our reading room. The reading room is located in room 1141 of the USDA South Building, 14th Street and Independence Avenue, SW...

Far-Ultraviolet Spectroscopy of Three Long-Period Novalike Variables

NASA Astrophysics Data System (ADS)

Bisol, Alexandra C.; Godon, Patrick; Sion, Edward M.

2012-02-01

We have selected three novalike variables at the long-period extreme of novalike orbital periods: V363 Aur, RZ Gru, and AC Cnc, all with IUE archival far-ultraviolet spectra. All are UX UMa-type novalike variables and all have Porb > 7 hr. V363 Aur is a bona fide SW Sex star, and AC Cnc is a probable one, while RZ Gru has not proven to be a member of the SW Sex subclass. We have carried out the first synthetic spectral analysis of far-ultraviolet spectra of the three systems using state-of-the-art models of both accretion disks and white dwarf photospheres. We find that the FUV spectral energy distribution of both V363 Aur and RZ Gru are in agreement with optically thick steady-state accretion disk models in which the luminous disk accounts for 100% of the FUV light. We present accretion rates and model-derived distances for V363 Aur and RZ Gru. For AC Cnc, we find that a hot accreting white dwarf accounts for ˜60% of the FUV light, with an accretion disk providing the rest. We compare our accretion rates and model-derived distances with estimates in the literature.

Polariton Local States in Periodic Bragg Multiple Quantum Well Structures

NASA Astrophysics Data System (ADS)

Deych, Lev; Yamilov, Alexey; Lisyansky, Alexander

2000-11-01

We analytically study defect polariton states in Bragg MQW structures, and defect induced changes in transmission and reflection spectra. Defect layers can differ from the host layers in three different ways: in the exciton-light coupling strength, in the exciton resonance frequency, and in interwell spacing. We show that a single defect leads to two local polariton modes in the photonic band gap. These modes lead to peculiarities in reflection and transmission spectra. Each type of defect can be reproduced experimentally, and we show that each of them play distinctly different roles in the optical properties of the system. We obtain closed analytical expressions for respective local frequencies, as well as for reflection and transmission coefficients. On the basis of the results obtained, we give practical recommendation for experimental observation of the studied effects in samples used in Refs. [1,2]. [1] M.Hübner, J. Kuhl, T. Stroucken, A. Knorr, S.W. Koch, R. Hey, K. Ploog, Phys. Rev. Lett. 76, 4199 (1996). [2] M.Hübner, J.P. Prineas, C. Ell, P. Brick, E.S. Lee, G. Khitrova, H.M. Gibbs, S.W. Koch, Phys. Rev. Lett. 83, 2841 (1999).

Modern sediments and Pleistocene reefs from isolated carbonate platforms (Iles Eparses, SW Indian Ocean): A preliminary study

NASA Astrophysics Data System (ADS)

Jorry, Stéphan J.; Camoin, Gilbert F.; Jouet, Gwénaël; Roy, Pascal Le; Vella, Claude; Courgeon, Simon; Prat, Sophie; Fontanier, Christophe; Paumard, Victorien; Boulle, Julien; Caline, Bruno; Borgomano, Jean

2016-04-01

Isolated carbonate platforms occur throughout the geologic record, from Archean to present. Although the respective roles of tectonics, sediment supply and sea-level changes in the stratigraphical architecture of these systems are relatively well constrained, the details of the nature and controls on the variability of sedimentological patterns between and within individual geomorphologic units on platforms have been barely investigated. This study aims at describing and comparing geomorphological and sedimentological features of surficial sediments and fossil reefs from three isolated carbonate platforms located in the SW Indian Ocean (Glorieuses, Juan de Nova and Europa). These carbonate platforms are relatively small and lack continuous reef margins, which have developed only on windward sides. Field observations, petrographic characterization and grain-size analyses are used to illustrate the spatial patterns of sediment accumulation on these platforms. The internal parts of both Glorieuses and Juan de Nova platforms are blanketed by sand dunes with medium to coarse sands with numerous reef pinnacles. Skeletal components including coral, green algae, and benthic foraminifera fragments prevail in these sediments. Europa platform exhibits a similar skeletal assemblage dominated by coral fragments, with the absence of wave-driven sedimentary bodies. Fossil reefs from the Last interglacial (125,000 years BP) occur on the three platforms. At Glorieuses, a succession of drowned terraces detected on seismic lines is interpreted as reflecting the last deglacial sea-level rise initiated 20,000 years ago. These findings highlight the high potential of these platforms to study past sea-level changes and the related reef response, which remain poorly documented in the SW Indian Ocean.

Contribution of storms to shoreline changes in mesotidal dissipative beaches: case study in the Gulf of Cádiz (SW Spain)

NASA Astrophysics Data System (ADS)

Puig, María; Del Río, Laura; Plomaritis, Theocharis A.; Benavente, Javier

2016-12-01

In this study an analysis of storminess and rates of shoreline change is performed and discussed jointly in four geomorphological units of the Gulf of Cádiz (SW Spain) for the period of 1956-2010. For this purpose, storm events are identified based on the following characteristics: wave height above 2.5 m, a minimum duration of 12 h and events with calm periods of less than 24 h were considered as a single event. Subsequently, energy parameters are determined in order to characterize storm-induced impacts. Conversely, geographic information system (GIS) tools are used to measure shoreline changes in aerial photographs and orthophotographs of each site, selecting the high water line as shoreline proxy. Each geomorphological unit is divided into different behavioural patterns according to recorded coastal changes, so that each one shows a particular behaviour.In general the variability of shoreline changes that is explained by storms and the relation between storm parameters and coastal changes present better results in exposed areas (Cádiz and Vistahermosa) than in sheltered areas (Valdelagrana spit barrier) because the former are more sensitive to storm impacts. On the contrary, in areas where there is no relation between coastal changes and storm parameters (Valdelagrana and Sancti Petri sand spit), it is suggested that anthropogenic factors are the main forcing agents determining shoreline behaviour. However, in these areas the storminess also modulates coastline recession by increasing erosion when the number of storms is high.

Promiscuous Speciation with Gene Flow in Silverside Fish Genus Odontesthes (Atheriniformes, Atherinopsidae) from South Western Atlantic Ocean Basins

PubMed Central

García, Graciela; Ríos, Néstor; Gutiérrez, Verónica; Varela, Jorge Guerra; Bouza Fernández, Carmen; Pardo, Belén Gómez; Portela, Paulino Martínez

2014-01-01

The present paper integrates phylogenetic and population genetics analyses based on mitochondrial and nuclear molecular markers in silversides, genus Odontesthes, from a non-sampled area in the SW Atlantic Ocean to address species discrimination and to define Managements Units for sustainable conservation. All phylogenetic analyses based on the COI mitochondrial gene were consistent to support the monophyly of the genus Odontesthes and to include O. argentinensis, O. perugiae-humensis and some O. bonariensis haplotypes in a basal polytomy conforming a major derivative clade. Microsatellites data revealed somewhat higher genetic variability values in the O. argentinensis-perugia populations than in O. bonariensis and O. perugia-humensis taxa. Contrasting population genetics structuring emerged from mitochondrial and microsatellites analyses in these taxa. Whereas mitochondrial data supported two major groups (O. argentinensis-perugia-humensis vs. O. bonariensis-perugiae-humensis populations), microsatellite data detected three major genetic entities represented by O. bonariensis, O. perugiae-humensis and an admixture of populations belonging to O. argentinensis-perugiae respectively. Therefore, the star COI polytomy in the tree topology involving these taxa could be interpreted by several hypothetic scenarios such as the existence of shared ancestral polymorphisms, incomplete lineage sorting in a radiating speciation process and/or reticulation events. Present findings support that promiscuous and recent contact between incipient species sharing asymmetric gene flow exchanges, blurs taxa boundaries yielding complicated taxonomy and Management Units delimitation in silverside genus Odontesthes from SW Atlantic Ocean basins. PMID:25126842

Promiscuous speciation with gene flow in silverside fish genus Odontesthes (Atheriniformes, Atherinopsidae) from south western Atlantic Ocean basins.

PubMed

García, Graciela; Ríos, Néstor; Gutiérrez, Verónica; Varela, Jorge Guerra; Bouza Fernández, Carmen; Pardo, Belén Gómez; Portela, Paulino Martínez

2014-01-01

The present paper integrates phylogenetic and population genetics analyses based on mitochondrial and nuclear molecular markers in silversides, genus Odontesthes, from a non-sampled area in the SW Atlantic Ocean to address species discrimination and to define Managements Units for sustainable conservation. All phylogenetic analyses based on the COI mitochondrial gene were consistent to support the monophyly of the genus Odontesthes and to include O. argentinensis, O. perugiae-humensis and some O. bonariensis haplotypes in a basal polytomy conforming a major derivative clade. Microsatellites data revealed somewhat higher genetic variability values in the O. argentinensis-perugia populations than in O. bonariensis and O. perugia-humensis taxa. Contrasting population genetics structuring emerged from mitochondrial and microsatellites analyses in these taxa. Whereas mitochondrial data supported two major groups (O. argentinensis-perugia-humensis vs. O. bonariensis-perugiae-humensis populations), microsatellite data detected three major genetic entities represented by O. bonariensis, O. perugiae-humensis and an admixture of populations belonging to O. argentinensis-perugiae respectively. Therefore, the star COI polytomy in the tree topology involving these taxa could be interpreted by several hypothetic scenarios such as the existence of shared ancestral polymorphisms, incomplete lineage sorting in a radiating speciation process and/or reticulation events. Present findings support that promiscuous and recent contact between incipient species sharing asymmetric gene flow exchanges, blurs taxa boundaries yielding complicated taxonomy and Management Units delimitation in silverside genus Odontesthes from SW Atlantic Ocean basins.

Test Program of the "Combined Data and Power Management Infrastructure"

NASA Astrophysics Data System (ADS)

Eickhoff, Jens; Fritz, Michael; Witt, Rouven; Bucher, Nico; Roser, Hans-Peter

2013-08-01

As already published in previous DASIA papers, the University of Stuttgart, Germany, is developing an advanced 3-axis stabilized small satellite applying industry standards for command/control techniques and Onboard Software design. This satellite furthermore features an innovative hybrid architecture of Onboard Computer and Power Control and Distribution Unit. One of the main challenges was the development of an ultra-compact and performing Onboard Computer (OBC), which was intended to support an RTEMS operating system, a PUS standard based Onboard Software (OBSW) and CCSDS standard based ground/space communication. The developed architecture (see [1, 2, 3]) is called a “Combined Onboard Data and Power Management Infrastructure” - CDPI. It features: The OBC processor boards based on a LEON3FT architecture - from Aeroflex Inc., USA The I/O Boards for all OBC digital interfaces to S/C equipment (digital RIU) - from 4Links Ltd. UK CCSDS TC/TM decoder/encoder boards - with same HW design as I/O boards - just with limited number of interfaces. HW from 4Links Ltd, UK, driver SW and IP-Core from Aeroflex Gaisler, SE Analog RIU functions via enhanced PCDU from Vectronic Aerospace, D OBC reconfiguration unit functions via Common Controller - here in PCDU [4] The CDPI overall assembly is meanwhile complete and a exhaustive description can be found in [5]. The EM test campaign including the HW/SW compatibility testing is finalized. This comprises all OBC EM units, OBC EM assembly and the EM PCDU. The unit test program for the FM Processor-Boards and Power-Boards of the OBC are completed and the unit tests of FM I/O-Boards and CCSDS-Boards have been completed by 4Links at the assembly house. The subsystem tests of the assembled OBC also are completed and the overall System tests of the CDPI with system reconfiguration in diverse possible FDIR cases also reach the last steps. Still ongoing is the subsequent integration of the CDPI with the satellite's avionics components encompassing TTC, AOCS, Power and Payload Control. This paper provides a full picture of the test campaign. Further details can be taken from