Sample records for units compatibility studies

  1. Two-digit number comparison: Decade-unit and unit-decade produce the same compatibility effect with number words.

    PubMed

    Macizo, Pedro; Herrera, Amparo

    2010-03-01

    This study explored the processing of 2-digit number words by examining the unit-decade compatibility effect in Spanish. Participants were required to choose the larger of 2-digit number words presented in verbal notation. In compatible trials the decade and unit comparisons led to the same response (e.g., 53-68) while in incompatible trials the decade and unit comparisons led to different responses (e.g., 59-74). Participants were slower on compatible trials as compared to incompatible trials. In Experiments 2 and 3, we evaluated whether the reverse compatibility effect in Spanish was only due to a pure left-to-right encoding which favours the decade processing in this language (decade-unit order). When participants processed 2-digit number words presented in reverse form (in the unit-decade order), the same reverse compatibility effect was found. This pattern of results suggests that participants have learnt a language-dependent process for analysing written numbers which is used irrespective of the specific arrangement of units and decades in the comparison task. 2010 APA, all rights reserved.

  2. Investigating the micromorphological differences of the implant-abutment junction and their clinical implications: a pilot study.

    PubMed

    Mattheos, Nikos; Li, Xiaona; Zampelis, Antonios; Ma, Li; Janda, Martin

    2016-11-01

    The aim of this pilot study was to investigate the morphological micro-features of three commercially available implant-abutment joints, using compatible and original prosthetic components. Furthermore, possible correlations between the micromorphology and potential functional complications were investigated with the use of finite element analysis. Three abutments (one original and two compatibles) were torqued on original Straumann RN implants, as according to each of the manufacturer's instructions. The implant-abutment units were sliced in the microtome and photographed under different magnifications (10×-500×) through a scanning electron microscope. Finite element analysis models were reconstructed for each of the implant-abutment units using the precise measurements from the SEM. Differences in stress, strain and deformation for the three different abutments were then calculated using ANSYS Workbench v13. Major dimensional differences were identified between all studied contact areas of the three units. The tight contact in the implant shoulder was similar in all three units, but engagement of the internal connection and, in particular, the anti-rotation elements was seriously compromised in the compatible abutments. One compatible abutment demonstrated compromised engagement of the abutment screw as well. Equivalent stress and strain in the FEA were much higher for the compatible abutments. An evaluation of the sequence of preload application revealed differences in the pattern of deformation between the original and compatible abutments, which can have serious clinical implications. Compatible abutments can present critical morphological differences from the original ones. The differences in the cross-sectional geometry result in large differences in the overall contact areas, both in terms of quality and quantity which could have serious implications for the long-term stability of the prosthesis. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Milliwatt Generator Project

    NASA Astrophysics Data System (ADS)

    Latimer, T. W.; Rinehart, G. H.

    1992-05-01

    This report covers progress on the Milliwatt Generator Project from April 1986 through March 1988. Activities included fuel processing and characterization, production of heat sources, fabrication of pressure-burst test units, compatibility studies, impact testing, and examination of surveillance units. The major task of the Los Alamos Milliwatt Generator Project is to fabricate MC2893A heat sources (4.0 W) for MC2730A radioisotope thermoelectric generators (RTG's) and MC3599 heat sources (4.5 W) for MC3500 RTG's. The MWG Project interfaces with the following contractors: Sandia National Laboratories, Albuquerque (designer); E.I. du Pont de Nemours and Co. (Inc.), Savannah River Plant (fuel); Monsanto Research Corporation, Mound Facility (metal hardware); and General Electric Company, Neutron Devices Department (RTG's). In addition to MWG fabrication activities, Los Alamos is involved in (1) fabrication of pressure-burst test units, (2) compatibility testing and evaluation, (3) examination of surveillance units, and (4) impact testing and subsequent examination of compatibility and surveillance units.

  4. Effect of end segment on physicochemical properties and platelet compatibility of poly(propylene glycol)-initiated poly(methyl methacrylate).

    PubMed

    Fukuda, Chihiro; Yahata, Chie; Kinoshita, Takuya; Watanabe, Takafumi; Tsukamoto, Hideo; Mochizuki, Akira

    2017-10-01

    It is well known that polyether-based copolymers have good blood compatibility, although many mechanisms have been proposed to explain their favorable performance. Our objective in carrying out the present study was to obtain a better understanding of the effect of the (poly)ether segment on blood compatibility. Therefore, we synthesized poly(propylene glycol) (PPG)-based initiators for atom transfer polymerization, where the number of propylene glycol (PG) units in the PPG (Pn(PG) was varied from 1 to 94. Methyl methacrylate (MMA) was polymerized using the initiators, resulting in the formation of polyMMAs with a PG-based ether part at the polymer terminal. We mainly investigated the effects of Pn(PG) on the surface properties and platelet compatibility of the PPG-polyMMA. X-ray photoelectron spectroscopy and surface contact angle (CA) analysis revealed the exposure of the PG units at the surface of the polymer. The platelet compatibility of the polymers was improved compared with a commercial polyMMA, even when Pn(PG) = 1. These results suggest that PG units have an important influence on favorable blood compatibility, regardless of the Pn(PG) value. We also investigated protein adsorption behavior in terms of the amount and deformation of fibrinogen adsorbed on the polymer surface.

  5. Whorf Reloaded: Language Effects on Nonverbal Number Processing in First Grade--A Trilingual Study

    ERIC Educational Resources Information Center

    Pixner, S.; Moeller, K.; Hermanova, V.; Nuerk, H. -C.; Kaufmann, L.

    2011-01-01

    The unit-decade compatibility effect is interpreted to reflect processes of place value integration in two-digit number magnitude comparisons. The current study aimed at elucidating the influence of language properties on the compatibility effect of Arabic two-digit numbers in Austrian, Italian, and Czech first graders. The number word systems of…

  6. Testing a model of componential processing of multi-symbol numbers-evidence from measurement units.

    PubMed

    Huber, Stefan; Bahnmueller, Julia; Klein, Elise; Moeller, Korbinian

    2015-10-01

    Research on numerical cognition has addressed the processing of nonsymbolic quantities and symbolic digits extensively. However, magnitude processing of measurement units is still a neglected topic in numerical cognition research. Hence, we investigated the processing of measurement units to evaluate whether typical effects of multi-digit number processing such as the compatibility effect, the string length congruity effect, and the distance effect are also present for measurement units. In three experiments, participants had to single out the larger one of two physical quantities (e.g., lengths). In Experiment 1, the compatibility of number and measurement unit (compatible: 3 mm_6 cm with 3 < 6 and mm < cm; incompatible: 3 cm_6 mm with 3 < 6 but cm > mm) as well as string length congruity (congruent: 1 m_2 km with m < km and 2 < 3 characters; incongruent: 2 mm_1 m with mm < m, but 3 > 2 characters) were manipulated. We observed reliable compatibility effects with prolonged reaction times (RT) for incompatible trials. Moreover, a string length congruity effect was present in RT with longer RT for incongruent trials. Experiments 2 and 3 served as control experiments showing that compatibility effects persist when controlling for holistic distance and that a distance effect for measurement units exists. Our findings indicate that numbers and measurement units are processed in a componential manner and thus highlight that processing characteristics of multi-digit numbers generalize to measurement units. Thereby, our data lend further support to the recently proposed generalized model of componential multi-symbol number processing.

  7. On the Development of the Mental Number Line: More, Less, or Never Holistic with Increasing Age?

    ERIC Educational Resources Information Center

    Nuerk, Hans-Christoph; Kaufmann, Liane; Zoppoth, Sabine; Willmes, Klaus

    2004-01-01

    Magnitude is assumed to be represented along a holistic mental number line in adults. However, the authors recently observed a unit-decade compatibility effect for 2-digit numbers that is inconsistent with this "holisticness" assumption (H.-C. Nuerk, U. Weger, & K. Willmes, 2001). This study used the compatibility effect to examine whether the…

  8. Compatibility of Space Nuclear Power Plant Materials in an Inert He/Xe Working Gas Containing Reactive Impurities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MM Hall

    2006-01-31

    A major materials selection and qualification issue identified in the Space Materials Plan is the potential for creating materials compatibility problems by combining dissimilar reactor core, Brayton Unit and other power conversion plant materials in a recirculating, inert He/Xe gas loop containing reactive impurity gases. Reported here are results of equilibrium thermochemical analyses that address the compatibility of space nuclear power plant (SNPP) materials in high temperature impure He gas environments. These studies provide early information regarding the constraints that exist for SNPP materials selection and provide guidance for establishing test objectives and environments for SNPP materials qualification testing.

  9. An MR-compatible neonatal incubator.

    PubMed

    Paley, M N J; Hart, A R; Lait, M; Griffiths, P D

    2012-07-01

    To develop a neonatal MR-compatible incubator for transporting babies between a neonatal intensive care unit and an MRI unit that is within the same hospital but geographically separate. The system was strapped to a standard MR-compatible patient trolley, which provides space for resuscitation outside the incubator. A constant-temperature exothermic heat pad was used to maintain temperature together with a logging fluoro-optic temperature monitor and alarm system. The system has been designed to accommodate standard knee-sized coils from the major MR manufacturers. The original incubator was constructed from carbon fibre, but this required modification to prevent radiofrequency shading artefacts due to the conducting properties of the carbon fibre. A high-tensile polyester material was used, which combined light weight with high impact strength. The system could be moved onto the patient bed with the coils and infant in place by one technologist. Studies in eight neonatal patients produced high quality 1.5 T MR images with low motion artefacts. The incubator should also be compatible with imaging in 3 T MR systems, although further work is required to establish this. Images were acquired using both rapid and high-resolution sequences, including three-dimensional volumes, proton spectra and diffusion weighting. The incubator provides a safe, quiet environment for neonates during transport and imaging, at low cost.

  10. An MR-compatible neonatal incubator

    PubMed Central

    Paley, M N J; Hart, A R; Lait, M; Griffiths, P D

    2012-01-01

    Objectives To develop a neonatal MR-compatible incubator for transporting babies between a neonatal intensive care unit and an MRI unit that is within the same hospital but geographically separate. Methods The system was strapped to a standard MR-compatible patient trolley, which provides space for resuscitation outside the incubator. A constant-temperature exothermic heat pad was used to maintain temperature together with a logging fluoro-optic temperature monitor and alarm system. The system has been designed to accommodate standard knee-sized coils from the major MR manufacturers. The original incubator was constructed from carbon fibre, but this required modification to prevent radiofrequency shading artefacts due to the conducting properties of the carbon fibre. A high-tensile polyester material was used, which combined light weight with high impact strength. The system could be moved onto the patient bed with the coils and infant in place by one technologist. Results Studies in eight neonatal patients produced high quality 1.5 T MR images with low motion artefacts. The incubator should also be compatible with imaging in 3 T MR systems, although further work is required to establish this. Images were acquired using both rapid and high-resolution sequences, including three-dimensional volumes, proton spectra and diffusion weighting. Conclusion The incubator provides a safe, quiet environment for neonates during transport and imaging, at low cost. PMID:22167517

  11. Calcium Chloride in Neonatal Parenteral Nutrition Solutions with and without Added Cysteine: Compatibility Studies Using Laser and Micro-Flow Imaging Methodology.

    PubMed

    Huston, Robert K; Christensen, J Mark; Alshahrani, Sultan M; Mohamed, Sumeia M; Clark, Sara M; Nason, Jeffrey A; Wu, Ying Xing

    2015-01-01

    Previous studies of compatibility of calcium chloride (CaCl2) and phosphates have not included particle counts in the range specified by the United States Pharmacopeia. Micro-flow imaging techniques have been shown to be comparable to light obscuration when determining particle count and size in pharmaceutical solutions. The purpose of this study was to do compatibility testing for parenteral nutrition (PN) solutions containing CaCl2 using dynamic light scattering and micro-flow imaging techniques. Solutions containing TrophAmine (Braun Medical Inc, Irvine, CA), CaCl2, and sodium phosphate (NaPhos) were compounded with and without cysteine. All solutions contained standard additives to neonatal PN solutions including dextrose, trace metals, and electrolytes. Control solutions contained no calcium or phosphate. Solutions were analyzed for particle size and particle count. Means of Z-average particle size and particle counts of controls were determined. Study solutions were compared to controls and United States Pharmacopeia (USP) Chapter 788 guidelines. The maximum amount of Phos that was compatible in solutions that contained at least 10 mmol/L of Ca in 2.5% amino acids (AA) was determined. Compatibility of these solutions was verified by performing analyses of 5 repeats of these solutions. Microscopic analyses of the repeats were also performed. Amounts of CaCl2 and NaPhos that were compatible in solutions containing 1.5%, 2%, 2.5%, and 3% AA were determined. The maximum amount of NaPhos that could be added to TrophAmine solutions of > = 2.5% AA containing at least 10 mmol/L of CaCl2 was 7.5 mmol/L. Adding 50 mg/dL of cysteine increased the amount of NaPhos that could be added to solutions containing 10 mmol/L of CaCl2 to 10 mmol/L. Calcium chloride can be added to neonatal PN solutions containing NaPhos in concentrations that can potentially provide an intravenous intake of adequate amounts of calcium and phosphorus.

  12. Entrenched Enemies, Tactical Partners, or Steadfast Allies? Exploring the Fault Lines between Teacher Unions and Community Organizing in the United States

    ERIC Educational Resources Information Center

    Shirley, Dennis

    2016-01-01

    Teachers' unions and community organizing emerged out of shared collective struggles for social justice in the United States in the twentieth century. Beyond broad general aspirations for a better society, however, their interests and tactics have not always been compatible. This interpretive essay revisits three recent case studies of interaction…

  13. 77 FR 59702 - Promoting U.S. EC Regulatory Compatibility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... TRADE REPRESENTATIVE Promoting U.S. EC Regulatory Compatibility AGENCY: Office of the United... and European Commission (EC) share the goal of reducing excessive regulatory costs, unjustified..., safety, welfare, and the environment. Promoting this goal will help businesses to grow, create jobs, and...

  14. UNITED STATES DEPARTMENT OF TRANSPORTATION GLOBAL POSITIONING SYSTEM (GPS) ADJACENT BAND COMPATIBILITY ASSESSMENT

    DOT National Transportation Integrated Search

    2018-04-01

    The goal of the U.S. Department of Transportation (DOT) Global Positioning System (GPS) Adjacent Band Compatibility Assessment is to evaluate the maximum transmitted power levels of adjacent band radiofrequency (RF) systems that can be tolerated by G...

  15. Combinatorial compatibility as habit-controlling factor in lysozyme crystallization II. Morphological evidence for tetrameric growth units

    NASA Astrophysics Data System (ADS)

    Strom, C. S.; Bennema, P.

    1997-03-01

    This work (Part II) explores the relation between units and morphology. It shows the equivalence in behaviour between the attachment energies and the results of Monte Carlo growth kinetics simulations. The energetically optimal combination of the F slices in 1 1 0, 0 1 1 and 1 1 1 in a monomolecular interpretation leads to unsatisfactory agreement with experimentally observed morphology. In a tetrameric (or octameric) interpretation, the unit cell must be subdivided self-consistently in terms of stable molecular clusters. Thus, the presence or absence of the 1 1 1 form functions as a direct experimental criterion for distinguishing between monomolecular growth layers, and tetrameric (or octameric) growth layers of the same composition, but subjected to the condition of combinatorial compatibility, as the F slices combine to produce the growth habit. When that condition is taken into account, the tetrameric (or octameric) theoretical morphology in the broken bond model is in good agreement with experiment over a wide range. Subjectmatter for future study is summarized.

  16. Tactical Sensors for Dispersed TNF (Tactical Nuclear Force) Units. Appendix 1.Tactical Sensory Survey.

    DTIC Science & Technology

    1983-06-30

    activating a separate transmitter, audible alarm, or contact closure. This sensor is compatible with any device that utilizes an input pulse or...transmitter, audible alarm, or contact closure. This sensor is compatible *i with any device that utilizes an output to produce an alarm. 110-4769-002. This...used to generate an alarm by activating a separate transmitter, audible alarm, or contact closure. This sensor is compatible with any device that

  17. Mycelial compatibility and aggressiveness comparison of Sclerotinia sclerotiorum isolates from Brazil and the United States

    USDA-ARS?s Scientific Manuscript database

    Variability of Sclerotinia sclerotiorum isolates collected in Brazil and the USA were determined by mycelial compatibility grouping (MCG) and inoculations of soybean cultivars. Two experiments for MCGs and two for aggressiveness were conducted with two sets of isolates. The first set included nine i...

  18. Three conceptual units for behavior

    PubMed Central

    Moxley, Roy

    1987-01-01

    Three generic units for behavior are examined in terms of their background: an if-then unit for stimulus and response (S-R), a holistic unit for Kantor's behavior segment, and an AB-because-of-C unit for Skinner's three-term contingency. The units are distinguished in terms of their respective historical backgrounds, causal modes, advantages, and disadvantages. The ways in which these units may be compatible are discussed. PMID:22477957

  19. Evaluation of an MR-compatible blood sampler for PET

    NASA Astrophysics Data System (ADS)

    Breuer, J.; Grazioso, R.; Zhang, N.; Schmand, M.; Wienhard, K.

    2010-10-01

    The integration of magnetic resonance imaging (MRI) and positron emission tomography (PET) is an upcoming hybrid imaging technique. Prototype scanners for pre-clinical and clinical research have been built and tested. However, the potential of the PET part can be better exploited if the arterial input function (AIF) of the administered tracer is known. This work presents a dedicated MR-compatible blood sampling system for precise measurement of the AIF in an MR-PET study. The device basically consists of an LSO/APD-detector assembly which performs a coincidence measurement of the annihilation photons resulting from positron decays. During the measurement, arterial blood is drawn continuously from an artery and lead through the detector unit. Besides successful tests of the MR compatibility and the detector performance, measurements of the AIF of rats have been carried out. The results show that the developed blood sampling system is a practical and reliable tool for measuring the AIF in MR-PET studies.

  20. Mexican-Trained Educators in the United States: Our Assumptions--Their Beliefs.

    ERIC Educational Resources Information Center

    Maroney, Oanh H.; Smith, Howard L.

    A study examined the beliefs and attitudes of Mexican-trained educators regarding instruction for minority and language minority students in light of assumptions that students experience better outcomes with culturally and linguistically compatible teachers. Fifteen educators who received their teacher education in Mexico, and whose native…

  1. Development of a simple MR-compatible vibrotactile stimulator using a planar-coil-type actuator.

    PubMed

    Kim, Hyung-Sik; Choi, Mi-Hyun; Chung, Yoon-Gi; Kim, Sung-Phil; Jun, Jae-Hoon; Park, Jang-Yeon; Yi, Jeong-Han; Park, Jong-Rak; Lim, Dae-Woon; Chung, Soon-Cheol

    2013-06-01

    For this study, we developed a magnetic resonance (MR)-compatible vibrotactile stimulator using a planar-coil-type actuator. The newly developed vibrotactile stimulator consists of three units: control unit, drive unit, and planar-coil-type actuator. The control unit controls frequency, intensity, time, and channel, and transfers the stimulation signals to the drive unit. The drive unit operates the planar-coil-type actuator in response to commands from the control unit. The planar-coil-type actuator, which uses a planar coil instead of conventional electric wire, generates vibrating stimulation through interaction of the current of the planar coil with the static magnetic field of the MR scanner. Even though the developed tactile stimulating system is small, simple, and inexpensive, it has a wide range of stimulation frequencies (20 ~ 400 Hz, at 40 levels) and stimulation intensities (0 ~ 7 V, at 256 levels). The stimulation intensity does not change due to frequency changes. Since the transient response time is a few microseconds, the stimulation time can be controlled on a scale of microseconds. In addition, this actuator has the advantages of providing highly repeatable stimulation, being durable, being able to assume various shapes, and having an adjustable contact area with the skin. The new stimulator operated stably in an MR environment without affecting the MR images. Using functional magnetic resonance imaging, we observed the brain activation changes resulting from stimulation frequency and intensity changes.

  2. Earth Observatory Satellite system definition study. Report no. 6: Space shuttle interfaces/utilization

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The impacts of achieving compatibility of the Earth Observatory Satellite (EOS) with the space shuttle and the potential benefits of space shuttle utilization are discussed. Mission requirements and mission suitability, including the effects of multiple spacecraft missions, are addressed for the full spectrum of the missions. Design impact is assessed primarily against Mission B, but unique requirements reflected by Mission A, B, and C are addressed. The preliminary results indicated that the resupply mission had the most pronounced impact on spacecraft design and cost. Program costs are developed for the design changes necessary to achieve EOS-B compatibility with Space Shuttle operations. Non-recurring and recurring unit costs are determined, including development, test, ground support and logistics, and integration efforts. Mission suitability is addressed in terms of performance, volume, and center of gravity compatibility with both space shuttle and conventional launch vehicle capabilities.

  3. 46 CFR 64.89 - Cargo pump unit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... discharges a portable tank must be— (1) Constructed of materials that are compatible with the product to be...) The cargo pump power unit must be— (1) Diesel; (2) Hydraulic; (3) Pneumatic; or (4) Electric. (c) The...

  4. Effects of visual cue and response assignment on spatial stimulus coding in stimulus-response compatibility.

    PubMed

    Nishimura, Akio; Yokosawa, Kazuhiko

    2012-01-01

    Tlauka and McKenna ( 2000 ) reported a reversal of the traditional stimulus-response compatibility (SRC) effect (faster responding to a stimulus presented on the same side than to one on the opposite side) when the stimulus appearing on one side of a display is a member of a superordinate unit that is largely on the opposite side. We investigated the effects of a visual cue that explicitly shows a superordinate unit, and of assignment of multiple stimuli within each superordinate unit to one response, on the SRC effect based on superordinate unit position. Three experiments revealed that stimulus-response assignment is critical, while the visual cue plays a minor role, in eliciting the SRC effect based on the superordinate unit position. Findings suggest bidirectional interaction between perception and action and simultaneous spatial stimulus coding according to multiple frames of reference, with contribution of each coding to the SRC effect flexibly varying with task situations.

  5. Compatible taper equation for loblolly pine

    Treesearch

    J. P. McClure; R. L. Czaplewski

    1986-01-01

    Cao's compatible, segmented polynomial taper equation (Q. V. Cao, H. E. Burkhart, and T. A. Max. For. Sci. 26: 71-80. 1980) is fitted to a large loblolly pine data set from the southeastern United States. Equations are presented that predict diameter at a given height, height to a given top diameter, and volume below a given position on the main stem. All...

  6. Experimental Interactions of Components of Hemodialysis Units with Human Blood

    PubMed Central

    Zucker, W. H.; Shinoda, B. A.; Mason, R. G.

    1974-01-01

    An in vitro model test system for estimation of the blood compatibility of hemodialysis membranes and tubing is described. The model test system consists of a modified hemodialysis unit and blood pump through which fresh citrated human blood is circulated. The effects of the use of different pump and tubing types upon hematologic and blood coagulation parameters are described. Preexposure of test surfaces to albumin appeared to enhance blood compatibility characteristics of the model test system, whereas preexposure to a high density lipoprotein preparation or a proteinpolysaccharide preparation was without appreciable benefit. Use of blood from subjects receiving aspirin resulted in enhanced blood compatibility in the test system as did use of heparin. Use of Warfarin or dextran did not appear to enhance blood compatibility of test surfaces under the conditions of this test system. Dialysis membranes and tubing which formed parts of the test system were examined by scanning and transmission electron microscopy in control tests and in tests for effects of proteins and antithrombotic agents. ImagesFig 5Fig 6Fig 7Fig 8Fig 9Fig 10Fig 11Fig 12Fig 13Fig 14Fig 1Fig 2Fig 3Fig 4 PMID:4825611

  7. The Integration of Psycholinguistic and Discourse Processing Theories of Reading Comprehension.

    ERIC Educational Resources Information Center

    Beebe, Mona J.

    To assess the compatibility of miscue analysis and recall analysis as independent elements in a theory of reading comprehension, a study was performed that operationalized each theory and separated its components into measurable units to allow empirical testing. A cueing strategy model was estimated, but the discourse processing model was broken…

  8. Recent trends in preservative treatments for timber bridges

    Treesearch

    James P. Wacker

    2004-01-01

    An overview of wood preservatives currently used for timber bridges is presented through a series of case studies from different regions of the United States. New wood species and preservative treatment options for timber bridges have made choosing the appropriate preservative more complicated. The compatibility of wood species and preservative treatment is often...

  9. Average activity of excitatory and inhibitory neural populations

    NASA Astrophysics Data System (ADS)

    Roulet, Javier; Mindlin, Gabriel B.

    2016-09-01

    We develop an extension of the Ott-Antonsen method [E. Ott and T. M. Antonsen, Chaos 18(3), 037113 (2008)] that allows obtaining the mean activity (spiking rate) of a population of excitable units. By means of the Ott-Antonsen method, equations for the dynamics of the order parameters of coupled excitatory and inhibitory populations of excitable units are obtained, and their mean activities are computed. Two different excitable systems are studied: Adler units and theta neurons. The resulting bifurcation diagrams are compared with those obtained from studying the phenomenological Wilson-Cowan model in some regions of the parameter space. Compatible behaviors, as well as higher dimensional chaotic solutions, are observed. We study numerical simulations to further validate the equations.

  10. Average activity of excitatory and inhibitory neural populations

    PubMed Central

    Mindlin, Gabriel B.

    2016-01-01

    We develop an extension of the Ott-Antonsen method [E. Ott and T. M. Antonsen, Chaos 18(3), 037113 (2008)] that allows obtaining the mean activity (spiking rate) of a population of excitable units. By means of the Ott-Antonsen method, equations for the dynamics of the order parameters of coupled excitatory and inhibitory populations of excitable units are obtained, and their mean activities are computed. Two different excitable systems are studied: Adler units and theta neurons. The resulting bifurcation diagrams are compared with those obtained from studying the phenomenological Wilson-Cowan model in some regions of the parameter space. Compatible behaviors, as well as higher dimensional chaotic solutions, are observed. We study numerical simulations to further validate the equations. PMID:27781447

  11. Visual compatibility of defibrotide with selected drugs during simulated Y-site administration.

    PubMed

    Correard, Florian; Savry, Amandine; Gauthier-Villano, Laurence; Pisano, Pascale; Pourroy, Bertrand

    2014-08-01

    The visual compatibility of a solution of defibrotide (the only drug recommended for treatment and prophylaxis of hepatic venoocclusive disease) with solutions of various drugs commonly administered in bone marrow transplant procedures was studied. Solutions of 43 drug products in concentrations typically used in clinical practice were evaluated in 1:1 mixtures with defibrotide solution in glass tubes kept at room temperature. The evaluated products included antiinfectious, corticoid, sedative, analgesic, and cardiovascular agents widely used for hematopoietic stem cell transplantation and other marrow transplant procedures; in most cases, test solutions were prepared via dilution in or reconstitution with sterile water, 0.9% sodium chloride injection, or 5% dextrose injection. The mixtures were visually observed immediately after manual mixing and at specified time points (60, 150, and 240 minutes). Visual compatibility was defined as the absence of color change, haze, fibers, particles, gas generation, and precipitate formation. The effect of mixing order on visual compatibility was ascertained. Of the 43 tested drug solutions, 36 were found to be visually compatible with the defibrotide solution over the entire four-hour study period. Solutions of 7 drugs (amikacin, furosemide, midazolam, mycophenolate mofetil, nicardipine, tobramycin, and vancomycin) were visually incompatible with defibrotide solution. In some cases, evidence of incompatibility was observed intermittently or was dependent on mixing order. Defibrotide solution was found to be visually compatible with solutions of 36 i.v. products that are likely to be coadministered with the drug in a bone marrow transplant unit. Seven drug solutions were visually incompatible with defibrotide solution. Copyright © 2014 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  12. 50 CFR 26.41 - What is the process for determining if a use of a national wildlife refuge is a compatible use?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false What is the process for determining if a use of a national wildlife refuge is a compatible use? 26.41 Section 26.41 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE...

  13. 50 CFR 26.41 - What is the process for determining if a use of a national wildlife refuge is a compatible use?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false What is the process for determining if a use of a national wildlife refuge is a compatible use? 26.41 Section 26.41 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE...

  14. 50 CFR 26.41 - What is the process for determining if a use of a national wildlife refuge is a compatible use?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false What is the process for determining if a use of a national wildlife refuge is a compatible use? 26.41 Section 26.41 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE...

  15. 50 CFR 26.41 - What is the process for determining if a use of a national wildlife refuge is a compatible use?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false What is the process for determining if a use of a national wildlife refuge is a compatible use? 26.41 Section 26.41 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE...

  16. 50 CFR 26.41 - What is the process for determining if a use of a national wildlife refuge is a compatible use?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false What is the process for determining if a use of a national wildlife refuge is a compatible use? 26.41 Section 26.41 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) THE NATIONAL WILDLIFE...

  17. Forest statistics for West-Central Tennessee counties - 1989

    Treesearch

    Dennis M. May; John S. Vissage

    1989-01-01

    Tabulated results were derived from data obtained during a recent inventory of 11 counties comprising the West-Central unit of Tennessee (fig. 1). Tables 1-25 were developed to provide compatibility among Forest Inventory and Analysis Projects. Tables 26-40 are supplementary tables and may change from unit to unit or State to State to address specific resource issues...

  18. Stability and compatibility assessment techniques for total parenteral nutrition admixtures: setting the bar according to pharmacopeial standards.

    PubMed

    Driscoll, David F

    2005-05-01

    The stability and compatibility of total parenteral nutrition mixtures compounded for patients requiring nutritional support is paramount to their safety on intravenous infusion. The most significant pharmaceutical issues associated with mixing total parenteral nutrition formulations affecting their safety involve the stability of lipid-injectable emulsions and the compatibility of calcium and phosphate salts. Methods of analysis for stability and compatibility have varied, and the assessments have mostly been largely qualitative. Although pharmacopeial standards have been primarily applicable to pharmaceutical manufacturers, recent efforts by the United States Pharmacopeia have been directed at standardizing pharmacy practices involved in the safe mixing of compounded sterile preparations. The adoption of chapter 797 entitled 'Pharmaceutical compounding - sterile preparations' on 1 January 2004 has had a dramatic impact on pharmacy practice in the United States. More recently, the United States Pharmacopeia has also proposed a new chapter 729 entitled 'Globule size distribution in lipid-injectable emulsions', setting specific limits on the sizes and concentrations of lipid droplets in the formulation, which may have implications for all-in-one mixtures. Finally, new efforts are under way to establish limits on the level of acceptable amounts of particulates intrinsically introduced by the manufacturer, and thus may have ramifications for particulates extrinsically introduced or initiated during compounding by the pharmacist. With careful monitoring and the development of appropriate pharmacopeial-based specifications that limit the size and concentration of large-diameter fat globules and eliminate the possibility of dibasic calcium phosphate precipitates, improved patient outcomes may be achieved.

  19. Conflict resolution in two-digit number processing: evidence of an inhibitory mechanism.

    PubMed

    Macizo, Pedro

    2017-01-01

    We investigated the mechanism involved in conflict resolution when individuals processed two-digit numbers. Participants performed a comparison task in blocks of two trials. In the first trial, between-decade two-digit numbers were used in a compatible condition where the decade and the unit of one number were larger than those of the other number (i.e., 21-73) and an incompatible condition where the decade of one number was larger but the unit was smaller than those of the other number (i.e., 61-53). In the second trial, within-decade two-digit numbers were presented in a related condition where the numbers contained the units presented previously (i.e., 41-43) and an unrelated condition with units that did not appear before (i.e., 48-49). In the first trial, participants responded more slowly in incompatible trials relative to compatible trials. In the second trial, participants were slower in the related condition relative to unrelated trials only after incompatible trials. These results suggest that participants experienced conflict in the incompatible condition of first trial and that they inhibited irrelevant units to resolve conflict.

  20. Speaking two languages with different number naming systems: What implications for magnitude judgments in bilinguals at different stages of language acquisition?

    PubMed

    Van Rinsveld, Amandine; Schiltz, Christine; Landerl, Karin; Brunner, Martin; Ugen, Sonja

    2016-08-01

    Differences between languages in terms of number naming systems may lead to performance differences in number processing. The current study focused on differences concerning the order of decades and units in two-digit number words (i.e., unit-decade order in German but decade-unit order in French) and how they affect number magnitude judgments. Participants performed basic numerical tasks, namely two-digit number magnitude judgments, and we used the compatibility effect (Nuerk et al. in Cognition 82(1):B25-B33, 2001) as a hallmark of language influence on numbers. In the first part we aimed to understand the influence of language on compatibility effects in adults coming from German or French monolingual and German-French bilingual groups (Experiment 1). The second part examined how this language influence develops at different stages of language acquisition in individuals with increasing bilingual proficiency (Experiment 2). Language systematically influenced magnitude judgments such that: (a) The spoken language(s) modulated magnitude judgments presented as Arabic digits, and (b) bilinguals' progressive language mastery impacted magnitude judgments presented as number words. Taken together, the current results suggest that the order of decades and units in verbal numbers may qualitatively influence magnitude judgments in bilinguals and monolinguals, providing new insights into how number processing can be influenced by language(s).

  1. Inventory and analysis of leafy spurge (Euphorbia esula) sites: a feasibility study

    Treesearch

    Richard E. Francis; Meredith J. Morris; Richard J. Myhre; Daniel L. Noble

    1980-01-01

    Leafy spurge (Euphorbia esula L.) infests more than 2.25 million acres of agricultural and range lands in the United States and had an economic impact of $10.5 million in 1978 (Noble et al. 1979). The most widespread and heaviest areas of infestation are in the northern and central Great Plains. However, quantitative information and compatible...

  2. C-MOS array design techniques: SUMC multiprocessor system study

    NASA Technical Reports Server (NTRS)

    Clapp, W. A.; Helbig, W. A.; Merriam, A. S.

    1972-01-01

    The current capabilities of LSI techniques for speed and reliability, plus the possibilities of assembling large configurations of LSI logic and storage elements, have demanded the study of multiprocessors and multiprocessing techniques, problems, and potentialities. Evaluated are three previous systems studies for a space ultrareliable modular computer multiprocessing system, and a new multiprocessing system is proposed that is flexibly configured with up to four central processors, four 1/0 processors, and 16 main memory units, plus auxiliary memory and peripheral devices. This multiprocessor system features a multilevel interrupt, qualified S/360 compatibility for ground-based generation of programs, virtual memory management of a storage hierarchy through 1/0 processors, and multiport access to multiple and shared memory units.

  3. Physical Compatibility of Sodium Glycerophosphate and Calcium Gluconate in Pediatric Parenteral Nutrition Solutions.

    PubMed

    MacKay, Mark; Anderson, Collin

    2015-08-01

    The solubility of inorganic calcium and phosphate in parenteral solutions can be complicated in pediatrics due to the dosing of calcium and phosphorus at the saturation point. The purpose of this study was to test the solubility of sodium glycerophosphate (NaGP) with calcium gluconate in pediatric parenteral nutrition (PN) solutions. Five PN solutions were compounded by adding calcium gluconate at 10, 20, 30, 40, and 50 mEq/L and corresponding concentrations of NaGP at 10, 20, 30, 40, and 50 mmol/L. Each of the 5 solutions was compounded using 1.5% and 4% amino acids, cysteines, and lipids. Compatibility was evaluated by visual inspection (precipitation, haze, and color change). Solutions were evaluated microscopically for any microcrystals and measured by a turbidimeter for changes in turbidity. Solutions were further analyzed using United States Pharmacopeia 788 standards. Six hundred seventy-one PN solutions were compounded at various concentrations and evaluated for visual stability. Compatibility testing showed no changes in the PN solution in any of the concentrations tested. Microscopically, no microcrystals were detected. The turbidimeter measurements had changes of ≤ 0.14 nephelometric turbidity units for all test solutions. There were no visual changes in any of the 671 PN solutions. It is recommended that NaGP replace sodium phosphate in PN solutions. This would eliminate the concern of calcium and phosphorus precipitation and the need of any saturation curves. © 2014 American Society for Parenteral and Enteral Nutrition.

  4. Forest statistics for Southwest Mississippi counties - 1994

    Treesearch

    Joanne L. Faulkner; Andrew J. Hartsell; Jack D. London

    1995-01-01

    Tabulated results were derived from data obtained during a 1994 forest inventory of southwest Mississippi counties (fig. I). These data are considered preliminary. Field work was conducted from February to august 1994. Core tables 1 through 25 are compatible among forest Inventory and Analysis (FIA) units in the Eastern United States. Supplemental tables 26 through 44...

  5. Physical compatibility of various drugs with neonatal total parenteral nutrient solution during simulated Y-site administration.

    PubMed

    Fox, Laura M; Wilder, Alyson G; Foushee, Jaime A

    2013-03-15

    The physical compatibility of various drugs with neonatal total parenteral nutrient (TPN) solution during simulated Y-site administration was evaluated. Study drugs were selected based on the lack of compatibility data with them and neonatal TPN solution and the frequency of use in a local neonatal unit. These drugs included amiodarone, caffeine citrate, clindamycin, enalaprilat, epinephrine, fluconazole, fosphenytoin sodium, hydrocortisone, metoclopramide, midazolam, pentobarbital, phenobarbital, and rifampin. Equal volumes of neonatal TPN solution or sterile water for injection were combined with study drugs or sterile water for injection at concentrations used clinically in neonates. Each test was performed in triplicate. The samples were examined via turbidimetric analysis and visually against light and dark backgrounds immediately after mixing and at 0.25, 0.5, 1, 2, and 3 hours after mixing. Analysis of variance was used to determine statistically significant differences between the test and control solutions. Many of the drugs studied exhibited no visual or turbidimetric evidence of incompatibility when combined with neonatal TPN solution for up to three hours in a simulated Y-site injection. Pentobarbital, phenobarbital, and rifampin formed visible precipitation immediately after mixing with the neonatal TPN solution. Caffeine citrate, clindamycin, enalaprilat, epinephrine, fluconazole, fosphenytoin sodium, hydrocortisone, metoclopramide, and midazolam exhibited no visual or turbidimetric evidence of incompatibility when combined with a neonatal TPN solution for up to three hours in a simulated Y-site injection. Amiodarone, pentobarbital, phenobarbital, and rifampin were not compatible with the neonatal TPN solution and should not be coadministered via Y-site injection.

  6. Apollo-Soyuz test project docking system

    NASA Technical Reports Server (NTRS)

    Swan, W. L., Jr.

    1976-01-01

    The United States and Soviet Union in July 1975 successfully completed a joint space mission utilizing each country's spacecraft and the compatible docking system designed and fabricated by each country. The compatible docking system is described, along with the extensive research, development, and testing leading up to the successful mission. It also describes the formulation and implementation of methods for breaking the language barrier, bridging the extensive distances for communication and travel, and adjusting to each country's different culture during the three-year development program.

  7. United States Air Force F-35A Operational Basing Environmental Impact Statement. Appendix E: Comments

    DTIC Science & Technology

    2013-09-01

    studies such as this one, and other research conducted in most recent decade. Of course, the housing designation ("not compatible with residential...such as final, technical, interim, memorandum, master’s thesis, progress, quarterly, research , special, group study, etc. 3. DATES COVERED...appear in the report, e.g. 001; AFAPL30480105. 6. AUTHOR(S). Enter name(s) of person(s) responsible for writing the report, performing the research

  8. Examining ABO compatible donors in double lung transplants during the era of lung allocation score.

    PubMed

    Taghavi, Sharven; Jayarajan, Senthil N; Furuya, Yuka; Komaroff, Eugene; Shiose, Akira; Leotta, Eros; Hisamoto, Kazuhiro; Patel, Namrata; Cordova, Francis; Criner, Gerard; Guy, T Sloane; Toyoda, Yoshiya

    2014-10-01

    The short-term and long-term effect of using ABO compatible donors in the era of lung allocation score is unknown. This study determined if carefully selected ABO compatible donors could be used in double lung transplantation (DLT) with good outcomes. The United Network for Organ Sharing database was retrospectively reviewed for adult DLT from May 2005 to December 2011. Of 6,655 double lung transplants, 493 (7.4%) were with ABO compatible donors and 6,162 (92.6%) were with ABO identical donors. In multivariate analysis, use of ABO compatible donors was not associated with mortality at 30 days (HR, 1.16; 95% CI, 0.76 to 1.79, p = 0.49), 1 year (HR, 1.10; 95% CI, 0.86 to 1.42, p = 0.46), and 5 years (HR, 1.06; 95% CI, 0.83 to 1.34, p = 0.65). Variables associated with mortality at 5 years were donor female sex, donor age 60 years or greater, prolonged ischemic time, increasing recipient creatinine, recipient age, race mismatch, and mechanical ventilation or extracorporeal membrane oxygenation as a bridge to transplantation. Length of stay was longer in the ABO compatible group (30.9 vs 25.9 days, p = 0.001). Acute rejection episodes on index hospitalization (8.8 vs. 8.9%, p = 1.00), peak posttransplant forced expiratory volume in 1 second (FEV1) (82.7 vs 79.7%, p = 0.053), and decrement in FEV1 over time were not different (p = 0.13). Freedom from bronchiolitis obliterans syndrome was similar (1,475 vs 1,454 days, p = 0.17). The use of ABO compatible donors in the era of lung allocation score was not associated with short-term or long-term mortality and resulted in equivalent posttransplant lung function. A DLT with carefully selected ABO compatible donors can result in excellent outcomes. Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  9. Building America Case Study: Assessment of a Hybrid Retrofit Gas Water Heater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    M. Hoeschele, E. Weitzel, C. Backman

    This project completed a modeling evaluation of a hybrid gas water heater that combines a reduced capacity tankless unit with a downsized storage tank. This product would meet a significant market need by providing a higher efficiency gas water heater solution for retrofit applications while maintaining compatibility with the half-inch gas lines and standard B vents found in most homes. The TRNSYS simulation tool was used to model a base case 0.60 EF atmospheric gas storage water, a 0.82 EF non-condensing gas tankless water heater, an existing (high capacity) hybrid unit on the market, and an alternative hybrid unit withmore » lower storage volume and reduced gas input requirements.« less

  10. Compatibility of pressure sensitive adhesives with recycling unit operations

    Treesearch

    David Bormett; Carl Houtman; Said Abubakr; Joseph Peng

    1999-01-01

    Removal of pressure sensitive adhesives (PSAs) from recovered paper is a major problem facing the paper recycling industry. As a result of a United States Postal Service (USPS) initiative, which currently purchases about 12% of domestic PSA production, a team was formed consisting of representatives from the USPS, the Forest Products Laboratory, Springborn Testing and...

  11. DC-to-DC power supply for light aircraft flight testing

    NASA Technical Reports Server (NTRS)

    Yost, S. R.

    1980-01-01

    The power supply unit was developed to serve as the power source for a loran-C receiver. The power supply can be connected directly to the aircraft's electrical system, and is compatible with either 14 or 28 volt electrical systems. Design specifications are presented for the unit along with a description of the circuit design.

  12. The Role of the National System of Research Coordinating Units in the Research-to-Practice Continuum.

    ERIC Educational Resources Information Center

    Huber, Jake

    Intended to stimulate and foster better communication, cooperation, and understanding between the National Institute of Education (NIE) and Research Coordinating Units (RCU) personnel, this report documents the compatibility between NIE's objectives and the current activities of the RCU's. In both general and specific terms, the activities of NIE…

  13. Software Measurement Guidebook. Version 02.00.02

    DTIC Science & Technology

    1992-12-01

    Compatibility Testing Process .............................. 9-5 Figure 9-3. Development Effort Planning Curve ................................. 9-7 Figure 10-1...requirements, design, code, and test and for analyzing this data. "* Proposal Manager. The person responsible for describing and supporting the estimated...designed, build/elease ranges, variances, and comparisons size growth; costs; completions; and content, units completing test , units with historical

  14. Joint Symposium on Compatibility of Plastics/Materials with Explosives Processing Explosives Held in Albuquerque, New Mexico on 15-17 May 1979.

    DTIC Science & Technology

    1979-05-01

    250 A. S. Tompa REAL-TIME LOW TEMPERATURE NC AND PBX 9404 DECOMPOSITION STUDIES ....................................... 276 ._- Dr. Hermann...the five major unit operations for multi-base cannon propellant; nitrocellulose dehydration , premixing, mixing, extruding and cutting. Throughout the...during facility design, a general process description is presented as follows: Thermal Dehydration Nitrocellulose (NC) slurry is fed to a continuous

  15. Magnetic resonance imaging-compatible tactile sensing device based on a piezoelectric array.

    PubMed

    Hamed, Abbi; Masamune, Ken; Tse, Zion Tsz Ho; Lamperth, Michael; Dohi, Takeyoshi

    2012-07-01

    Minimally invasive surgery is a widely used medical technique, one of the drawbacks of which is the loss of direct sense of touch during the operation. Palpation is the use of fingertips to explore and make fast assessments of tissue morphology. Although technologies are developed to equip minimally invasive surgery tools with haptic feedback capabilities, the majority focus on tissue stiffness profiling and tool-tissue interaction force measurement. For greatly increased diagnostic capability, a magnetic resonance imaging-compatible tactile sensor design is proposed, which allows minimally invasive surgery to be performed under image guidance, combining the strong capability of magnetic resonance imaging soft tissue and intuitive palpation. The sensing unit is based on a piezoelectric sensor methodology, which conforms to the stringent mechanical and electrical design requirements imposed by the magnetic resonance environment The sensor mechanical design and the device integration to a 0.2 Tesla open magnetic resonance imaging scanner are described, together with the device's magnetic resonance compatibility testing. Its design limitations and potential future improvements are also discussed. A tactile sensing unit based on a piezoelectric sensor principle is proposed, which is designed for magnetic resonance imaging guided interventions.

  16. 77 FR 40023 - 36(b)(1) Arms Sales Notification

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ... vision goggle compatible and sun light readable. The pilots and aircrew have common programmable keysets... pilots and aircrew have common programmable keysets, a mass memory unit, mission and flight management...

  17. Analysis of the safety evaluation for premarketing clinical trials of hemodialyzer and of postmarketing safety reports of hemodialyzer in Japan and the US: insights into the construction of a sophisticated premarketing evaluation.

    PubMed

    Saito, Masami; Iwasaki, Kiyotaka

    2017-03-01

    Our aim was to conduct a scoping review of the regulations for hemodialyzers in the safety evaluation in Japan and the United States, and to evaluate the criteria for premarketing clinical trials and postmarketing safety reports to inform the development of a sophisticated premarketing evaluation in Japan. Regulations for approval of hemodialyzers were identified from the databases of the Ministry of Health, Labor and Welfare in Japan and the Federal Drug Agency (FDA) in the United States (US). The criteria for premarket clinical trials and postmarketing safety reports were evaluated for both countries. Standards in Japan required evaluation of blood compatibility and reporting of acute adverse effects by a premarketing clinical trial in 6 of 86 applications with semipermeable membrane materials deemed to be different to those of previously approved devices from 1983 to 31 August 2015. By comparison, the clinical trial was required in one of 545 approvals in the US from 1976 to 29 January 2016, but blood compatibility was not the point. All postmarketing adverse effects identified in Japan were included in the set of 'warnings'. The more stringent requirements for evaluation of blood compatibility and acute adverse effects in Japan seemed to be related to differences in the history of quality management systems for medical devices between the two countries. This study revealed that there were differences between Japan and the US in requiring the premarketing clinical trials for the hemodialyzers. Our findings could be useful for constructing sophisticated premarketing safety evaluation.

  18. Which functional unit to identify sustainable foods?

    PubMed

    Masset, Gabriel; Vieux, Florent; Darmon, Nicole

    2015-09-01

    In life-cycle assessment, the functional unit defines the unit for calculation of environmental indicators. The objective of the present study was to assess the influence of two functional units, 100 g and 100 kcal (420 kJ), on the associations between three dimensions for identifying sustainable foods, namely environmental impact (via greenhouse gas emissions (GHGE)), nutritional quality (using two distinct nutrient profiling systems) and price. GHGE and price data were collected for individual foods, and were each expressed per 100 g and per 100 kcal. Two nutrient profiling models, SAIN,LIM and UK Ofcom, were used to assess foods' nutritional quality. Spearman correlations were used to assess associations between variables. Sustainable foods were identified as those having more favourable values for all three dimensions. The French Individual and National Dietary Survey (INCA2), 2006-2007. Three hundred and seventy-three foods highly consumed in INCA2, covering 65 % of total energy intake of adult participants. When GHGE and price were expressed per 100 g, low-GHGE foods had a lower price and higher SAIN,LIM and Ofcom scores (r=0·59, -0·34 and -0·43, respectively), suggesting a compatibility between the three dimensions; 101 and 100 sustainable foods were identified with SAIN,LIM and Ofcom, respectively. When GHGE and price were expressed per 100 kcal, low-GHGE foods had a lower price but also lower SAIN,LIM and Ofcom scores (r=0·67, 0·51 and 0·47, respectively), suggesting that more environment-friendly foods were less expensive but also less healthy; thirty-four sustainable foods were identified with both SAIN,LIM and Ofcom. The choice of functional unit strongly influenced the compatibility between the sustainability dimensions and the identification of sustainable foods.

  19. Proposed systems configurations for a satellite based ISDN

    NASA Astrophysics Data System (ADS)

    Capece, M.; Pavesi, B.; Tozzi, P.; Galligan, K. P.

    This paper summarizes concepts developed during a study for the ESA in which the evolution of ISDN capability and the impact in the satellite land mobile area are examined. Following the progressive steps of the expected ISDN implementation and the potential market penetration, a space based system capable of satisfying particular user services classes has been investigated. The approach used is to establish a comparison between the requirements of potential mobile users and the services already envisaged by ISDN, identifying the service subclasses that might be adopted in a mobile environment through a satellite system. Two system alternatives, with different ISDN compatibility, have been identified. The first option allows a partial compatibility, by providing the central stations of the earth segment with suitable interface units. The second option permits a full integration, operating on the satellite on-board capabilities.

  20. Development of Engine and Lubricant Interferant Substances

    DTIC Science & Technology

    1976-05-01

    manufacturer’s recommended surfacvant to water ratio. As indicated earlier, aqueous foams have been deceloped printa~rily for firefighting . The two...Foainer .. 8.. . . ... ? 12 Ingestant Gas Compatibility with Aqueous Foam . . . . . . . 29 !I i2 DEVELOPMENT OF ENGINE AND LUBRICANT INTERFERANT...association with an aqueous foam . Commercially-available aqueous foam generating units are available from a number of different sources. Large single units

  1. Solid polymer electrolyte (SPE) fuel cell technology program, phase 1/1A. [design and fabrication

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A solid polymer electrolyte fuel cell was studied for the purpose of improving the characteristics of the technology. Several facets were evaluated, namely: (1) reduced fuel cell costs; (2) reduced fuel cell weight; (3) improved fuel cell efficiency; and (4) increased systems compatibility. Demonstrated advances were incorporated into a full scale hardware design. A single cell unit was fabricated. A substantial degree of success was demonstrated.

  2. Alternatives to Weight Tolerance Permits

    DOT National Transportation Integrated Search

    2000-10-01

    A complex web of government regulations in the United States establishes maximum weights for vehicles on public roads. The primary purpose is to ensure compatibility of roadway design and operations with vehicle weight and dimensions. Of particular c...

  3. Effects of Thermal Exposure on the Optical Properties of LORD Aeroglaze A276

    NASA Technical Reports Server (NTRS)

    Ellis, David L.; Jaworske, Donald A.

    2009-01-01

    A lunar outpost will require electrical energy. One potential source is fission surface power where heat from a reactor is converted into electricity utilizing an energy conversion system, and waste heat will need to be rejected from the system. The Second Generation Radiator Demonstration Unit is a technology demonstration unit leading towards operational radiators. To approximate the infrared emittance of the lunar outpost radiators, a low-cost coating compatible with the test conditions was sought. LORD Aeroglaze A276 has a similar emittance, but its performance in air and vacuum at the desired operating temperatures was unknown. This study determined that the emittance remained above 0.86 for all conditions tested and that LORD Aeroglaze A276 is a suitable surrogate coating for the Second Generation Radiator Demonstration Unit.

  4. [Platelet allo-antibodies identification strategies for preventing and managing platelet refractoriness].

    PubMed

    Basire, A; Picard, C

    2014-11-01

    Platelet refractoriness is a serious complication for patients receiving recurrent platelet transfusions, which can be explained by non-immune and immune causes. Human Leukocyte Antigens (HLA) allo-immunization, especially against HLA class I, is the major cause for immune platelet refractoriness. To a lesser extent, allo-antibodies against specific Human Platelet Antigen (HPA) are also involved. Pregnancy, transplantation and previous transfusions can lead to allo-immune reaction against platelet antigens. After transfusion, platelet count is decreased by accelerated platelet destruction related to antibodies fixation on incompatible platelet antigens. New laboratory tests for allo-antibodies identification were developed to improve sensibility and specificity, especially with the LUMINEX(®) technology. The good use and interpretation of these antibodies assays can improve strategies for platelet refractoriness prevention and management with a patient adapted response. Compatible platelets units can be selected according to their identity with recipient typing or immune compatibility regarding HLA or HPA antibodies or HLA epitope compatibility. Prospective studies are needed to further confirm the clinical benefit of new allo-antibodies identification methods and consensus strategies for immune platelet refractoriness management. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  5. Efficacy of a care bundle to prevent multiple infections in the intensive care unit: A quasi-experimental pretest-posttest design study.

    PubMed

    Yazici, Gulay; Bulut, Hulya

    2018-02-01

    Healthcare-associated infections extend hospitalization time, increase treatment costs and increase morbidity-mortality rates. To evaluate the efficacy of a care bundle aimed at preventing three most frequent intensive care unit-acquired infections. This quasi-experimental study occurred in an 18-bed tertiary care intensive care unit at a university hospital in Turkey. The sample consisted of 120 patients older than 18years and receiving invasive mechanical ventilation therapy, or had a central venous catheter or urinary catheter. The study comprised three stages. In stage one, the intensive care unit nurses were trained in infection measures, VAP, CA-UTIs and CLABSIs sections of the care bundle. In stage two, the trained nurses applied the care bundle and received feedback on any problematic issues. In stage three, the nurses' compatibility and efficacy of the infection prevention care bundle on the infection rates of VAP, CA-UTIs and CLABSIs were evaluated over three 3-month periods. Over 1000 ventilation days, ventilator-associated pneumonia infection rates were 23.4, 12.6, and 11.5, during January-March, April-June and July-September, respectively, with January-March and April-June showing a significant decrease (χ 2 =6.934, p=0.031). The central line-associated bloodstream infection rates were 8.9, 4.2, and 9.9 per 1000 catheter days, during January-March, April-June and July-September, respectively, but were not significantly different based on pair-wise comparisons (p>0.05). The catheter-associated urinary tract infection rates were higher during July-September (6.7/1000 catheter days) compared to January-March (5.7/1000 catheter days) and April-June (10.4/1000 catheter days) but the differences were not significant (p>0.05). The infection rates decreased with increased compatibility of the care bundle prepared from evidence-based guidelines. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Evaluation of 100 brain examinations using a 3 Tesla MR-compatible incubator-safety, handling, and image quality.

    PubMed

    Sirin, Selma; Goericke, Sophia L; Huening, Britta M; Stein, Anja; Kinner, Sonja; Felderhoff-Mueser, Ursula; Schweiger, Bernd

    2013-10-01

    Several studies have revealed the importance of brain imaging in term and preterm infants. The aim of this retrospective study was to review safety, handling, and image quality of MR brain imaging using a new 3 Tesla MR-compatible incubator. Between 02/2011 and 05/2012 100 brain MRIs (84 infants, mean gestational age 32.2 ± 4.7 weeks, mean postmenstrual age at imaging 40.6 ± 3.4 weeks) were performed using a 3 Tesla MR-compatible incubator with dedicated, compatible head coil. Seventeen examinations (13 infants, mean gestational age 35.1 ± 5.4 weeks, mean postmenstrual age at imaging 47.8 ± 7.4 weeks) with a standard head coil served as a control. Image analysis was performed by a neuroradiologist and a pediatric radiologist in consensus. All but two patients with known apnea were transferred to the MR unit and scanned without problems. Handling was easier and faster with the incubator; relevant motion artifacts (5.9 vs. 10.8%) and the need for repetitive sedation (43.0 vs. 86.7%) were reduced. Considering only images not impaired by motion artifacts, image quality (4.8 ± 0.4 vs. 4.3 ± 0.8, p = 0.047) and spatial resolution (4.7 ± 0.4 vs. 4.2 ± 0.6, p = 0.011) of T2-weighted images were scored significantly higher in patients imaged with the incubator. SNR increased significantly (171.6 ± 54.5 vs. 80.5 ± 19.8, p < 0.001) with the use of the incubator. Infants can benefit from the use of a 3 Tesla MR-compatible incubator because of its safety, easier, and faster handling (compared to standard imaging) and possibility to obtain high-quality MR images even in unstable patients.

  7. Command, Control, Communications, Computers and Intelligence Electronic Warfare (C4IEW) Project Book, Fiscal Year 1994. (Non-FOUO Version)

    DTIC Science & Technology

    1994-04-01

    TSW-7A, AIR TRAFFIC CONTROL CENTRAL (ATCC) 32- 8 AN/TTC-41(V), CENTRAL OFFICE, TELEPHONE, AUTOMATIC 32- 9 MISSILE COUNTERMEASURE DEVICE (MCD) .- 0 MK...a Handheld Terminal Unit (HTU), Portable Computer Unit (PCU), Transportable Computer Unit (TCU), and compatible NOI peripheral devices . All but the...CLASSIFICATION: ASARC-III, Jun 80, Standard. I I I AN/TIC-39 IS A MOBILE , AUTOMATIC , MODULAR ELECTRONIC CIRCUIT SWITCH UNDER PROCESSOR CONTROL WITH INTEGRAL

  8. In vitro lysis and acute transfusion reactions with hemolysis caused by inappropriate storage of canine red blood cell products.

    PubMed

    Patterson, J; Rousseau, A; Kessler, R J; Giger, U

    2011-01-01

    Transfusion of red blood cell (RBC) products carries considerable risk for adverse reactions, including life-threatening hemolytic reactions. To report the occurrence and investigation of life-threatening acute transfusion reactions with hemolysis in dogs likely related to inappropriate blood product storage. Four dogs with acute transfusion reactions and other recipients of blood products. Medical records were reviewed from 4 dogs with suspected acute hemolytic transfusion reactions after receiving RBC products at a veterinary clinic over a 1-month period. Medical records of other animals receiving blood products in the same time period also were reviewed. Blood compatibility and product quality were assessed, subsequent transfusions were closely monitored, and products were diligently audited. During or immediately after RBC product transfusion, 4 dogs developed hemolysis, hemoglobinuria, or both. Two dogs died and 1 was euthanized because of progressive clinical signs compatible with an acute hemolytic transfusion reaction. Blood type and blood compatibility were confirmed. RBC units from 2 blood banks were found to be hemolyzed after storage in the clinic's refrigerator; no bacterial contamination was identified. After obtaining a new refrigerator dedicated to blood product storage, the problem of hemolyzed units and acute transfusion reactions with hemolysis completely resolved. Acute life-threatening transfusion reactions can be caused by inappropriate storage of RBC products. In addition to infectious disease screening and ensuring blood-type compatibility, quality assessment of blood products, appropriate collection, processing, and storage techniques as well as recipient monitoring are critical to provide safe, effective transfusions. Copyright © 2011 by the American College of Veterinary Internal Medicine.

  9. Aircraft Fire Safety

    DTIC Science & Technology

    1982-05-01

    these composites are bound with polymeric resins which burn even though the matrix such as Fiberglas or boron graphite will not. The third souce of...fuels, programs are underway to determine compatibility of the antimist additive with changes in base fuel compositions , such as increased aromatics...storage or an onboard oxygen/nitrogen separation unit. T se units are essentially based on semi-permeable hollow fibres and membranes together ith

  10. The 2017 MCWL/FD Initiative Portfolio

    DTIC Science & Technology

    2016-09-15

    maintaining compatibility with infantry weapon systems and human factors limitations. Non-Kinetic Engagement - Enable the rifle squad to disrupt enemy...provide robust, responsive, and accurate fires for distributed operations. Purpose: Determine weapons and equipment in order to provide organic fire... weapons , white trucks or other things of interest to the small unit. The system will identify the items and send alerts to the unit’s leader asking for

  11. Assessment of Interpersonal Risk (AIR) in Adults with Learning Disabilities and Challenging Behaviour--Piloting a New Risk Assessment Tool

    ERIC Educational Resources Information Center

    Campbell, Martin; McCue, Michael

    2013-01-01

    A new risk assessment tool, "Assessment of Interpersonal Risk" (AIR), was piloted and evaluated to measure risk factors and compatibility between individuals living in an assessment and treatment unit in one NHS area. The adults with learning disabilities in this unit had severe and enduring mental health problems and/or behaviour that is severely…

  12. 5 CFR 2416.103 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Assistant Attorney General, Civil Rights Division, United States Department of Justice. Auxiliary aids means... recordings, and other similar services and devices. Auxiliary aids useful for persons with impaired hearing include telephone handset amplifiers, telephones compatible with hearing aids, telecommunication devices...

  13. Integrated Advanced Microwave Sounding Unit-A (AMSU-A. Engineering Report: Electromagnetic Interface (EMI)/Electromagnetic Radiation (EMR) and Electromagnetic Compatibility (EMC), for the METSAT/METOP AMSU-A1

    NASA Technical Reports Server (NTRS)

    Valdez, A.

    1999-01-01

    This document contains the procedure and the test results of the Advanced Microwave Sounding Unit-A (AMSU-A) Electromagnetic Interference (EMI), Electromagnetic Susceptibility, and Electromagnetic Compatibility (EMC) qualification test for the Meteorological Satellite (METSAT) and the Meteorological Operation Platform (METOP) projects. The test was conducted in accordance with the approved EMI/EMC Test Plan/Procedure, Specification number AE-26151/5D. This document describes the EMI/EMC test performed by Aerojet and it is presented in the following manner: Section-1 contains introductory material and a brief summary of the test results. Section 2 contains more detailed descriptions of the test plan, test procedure, and test results for each type of EMI/EMC test conducted. Section 3 contains supplementary information that includes test data sheets, plots, and calculations collected during the qualification testing.

  14. System and Mass Storage Study for Defense Mapping Agency Topographic Center (DMATC/HC)

    DTIC Science & Technology

    1977-04-01

    34•»-—•—■»■—- view. The assessment should be based on carefully designed control condi- tions—data volume, resolution, function, etc...egories: hardware control and library management support. This software is designed to interface with IBM 360/370 OS and OS/VS. No interface with a...laser re- cording unit includes a programmable recorder control subsystem which can be designed to provide a hardware and software interface compatible

  15. Performance characterization of a low power hydrazine arcjet

    NASA Technical Reports Server (NTRS)

    Knowles, S. C.; Smith, W. W.; Curran, F. M.; Haag, T. W.

    1987-01-01

    Hydrazine arcjets, which offer substantial performance advantages over alternatives in geosynchronous satellite stationkeeping applications, have undergone startup, materials compatibility, lifetime, and power conditioning unit design issues. Devices in the 1000-3000 W output range have been characterized for several different electrode configurations. Constrictor length and diameter, electrode gap setting, and vortex strength have been parametrically studied in order to ascertain the influence of each on specific impulse and efficiency; specific impulse levels greater than 700 sec have been achieved.

  16. Space biology initiative program definition review. Trade study 6: Space Station Freedom/spacelab modules compatibility

    NASA Technical Reports Server (NTRS)

    Jackson, L. Neal; Crenshaw, John, Sr.; Davidson, William L.; Blacknall, Carolyn; Bilodeau, James W.; Stoval, J. Michael; Sutton, Terry

    1989-01-01

    The differences in rack requirements for Spacelab, the Shuttle Orbiter, and the United States (U.S.) laboratory module, European Space Agency (ESA) Columbus module, and the Japanese Experiment Module (JEM) of Space Station Freedom are identified. The feasibility of designing standardized mechanical, structural, electrical, data, video, thermal, and fluid interfaces to allow space flight hardware designed for use in the U.S. laboratory module to be used in other locations is assessed.

  17. On the functional role of human parietal cortex in number processing: How gender mediates the impact of a 'virtual lesion' induced by rTMS.

    PubMed

    Knops, Andre; Nuerk, Hans-Christoph; Sparing, Roland; Foltys, Henrik; Willmes, Klaus

    2006-01-01

    Areas around the horizontal part of the intraparietal sulcus (hIPS) have repeatedly been reported to participate in processing numerical magnitude. Using transcranial magnetic stimulation (TMS), we investigated the functional role of the hIPS by examining two effects from the domain of numerical cognition: in magnitude comparison tasks response latencies are inversely related to the numerical distance between two numbers. This distance effect indexes access to the mental number representation. In magnitude comparison tasks responses are faster when decade and unit comparison would lead to the same decision (e.g. 42_57, 4 < 5 and 2 < 7) than when they would not (e.g. 47_62, 4 < 6 but 7 > 2). This compatibility effect reflects unit-decade integration processes. Differential susceptibility of (fe)male participants to TMS was examined. We applied repetitive TMS (rTMS; 1Hz for 10 min) over the left hIPS in 12 participants (6 female). No stimulation and vertex stimulation served as control conditions. The effect of rTMS was mediated by gender: in male participants, the distance effect decreased after TMS over hIPS. For female participants distance and compatibility effect both increased. This modulation of the compatibility effect was limited in duration to no more than 4 min. The hIPS seems to be functionally involved both in number magnitude processing and in integrating unit-decade magnitude information of two-digit numbers. Relative hemispheric specialization of the hIPS with respect to two-digit magnitude comparison is discussed.

  18. Tin recycling in the United States in 1998

    USGS Publications Warehouse

    Carlin, James F.

    2001-01-01

    This materials flow study includes a description of tin supply and demand factors for the United States to illustrate the extent of tin recycling and to identify recycling trends. Understanding the flow of materials from source to ultimate disposition can assist in improving the management of the use of natural resources in a manner that is compatible with sound environmental practices. The quantity of tin recycled in 1998 as a percentage of apparent tin supply was estimated to be about 22%, and recycling efficiency was estimated to be 75%. Of the total tin consumed in products for the U.S. market in 1998, an estimated 12% was consumed in products where the tin was not recyclable (dissipative uses).

  19. Lead recycling in the United States in 1998

    USGS Publications Warehouse

    Smith, Gerald R.

    2001-01-01

    This materials flow study includes a description of lead supply and demand factors for the United States to illustrate the extent of lead recycling and to identify recycling trends. Understanding the system of materials flow from source to ultimate disposition can assist in improving the management of the use of natural resources in a manner that is compatible with sound environmental practices. The quantity of lead recycled in 1998, as a percentage of apparent lead supply, was estimated to be about 63%, and recycling efficiency, to be 95%. Of the total lead consumed in products for the U.S. market in 1998, an estimated 10% was consumed in products in which the lead was not readily recyclable.

  20. ZD multipurpose neurosurgical image-guided localizing unit: experience in 103 consecutive cases of open stereotaxis

    NASA Astrophysics Data System (ADS)

    Zamorano, Lucia J.; Dujovny, Manuel

    1991-05-01

    A unit is presented that provides the neurosurgeon with CT, MRI, x-ray, DA, and DSA compatible headholder and multimodality image localization as well as freedom of choice for surgical approach on patient's intraoperative positioning. The unit consists of a carbon fiber ring-shaped headholder which allows free selection for location of three or four fixation pins, avoiding interference with the flap sites or craniotomy. The base ring is mounted intraoperatively on a special adapter that allows any patient positioning including supine, lateral, prone, 3/4 prone, sitting, etc. Surgical draping can be performed given a completely sterile field. An arc/quadrant localizing device can be mounted on any four alternative positions according to the neurosurgeon's preference. A PC compatible software gives the setting for any possible mounting. Intraoperative the localizing unit can be used in a 'fixed' permanent setting or as a 'non-fixed' system to provide intraoperative three-dimensional orientation. Different are adapted instruments which give the unit further capabilities, especially 'bayonet' type brain retractors (cylinders and speculum) that allows the neurosurgeon to keep the surgical corridor unobstructed from the arc. As an alternative, in the 'non-fixed' setting, self-retaining arms are fixed to the base ring and brain retractors and conventional microsurgical technique can be used without any mechanical obstruction. This article presents the unit details, methodology and the clinical experience in 103 consecutive cases of 'open stereotaxis' for resection or internal decompression of deep seated or near eloquent area lesions.

  1. Nuclear electric propulsion mission engineering study. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Results of a mission engineering analysis of nuclear-thermionic electric propulsion spacecraft for unmanned interplanetary and geocentric missions are summarized. Critical technologies associated with the development of nuclear electric propulsion (NEP) are assessed. Outer planet and comet rendezvous mission analysis, NEP stage design for geocentric and interplanetary missions, NEP system development cost and unit costs, and technology requirements for NEP stage development are studied. The NEP stage design provides both inherent reliability and high payload mass capability. The NEP stage and payload integration was found to be compatible with the space shuttle.

  2. Large space erectable structures - building block structures study

    NASA Technical Reports Server (NTRS)

    Armstrong, W. H.; Skoumal, D. E.; Straayer, J. W.

    1977-01-01

    A modular planar truss structure and a long slender boom concept identified as building block approaches to construction of large spacecraft configurations are described. The concepts are compatible in weight and volume goals with the Space Transportation System, use standard structural units, and represent high on-orbit productivity in terms of structural area or beam length. Results of structural trade studies involving static and dynamic analyses of a single module and rigid body deployment analyses to assess kinetics and kinematics of automatic deployment of the building block modules are presented.

  3. Individual differences influence two-digit number processing, but not their analog magnitude processing: a large-scale online study.

    PubMed

    Huber, Stefan; Nuerk, Hans-Christoph; Reips, Ulf-Dietrich; Soltanlou, Mojtaba

    2017-12-23

    Symbolic magnitude comparison is one of the most well-studied cognitive processes in research on numerical cognition. However, while the cognitive mechanisms of symbolic magnitude processing have been intensively studied, previous studies have paid less attention to individual differences influencing symbolic magnitude comparison. Employing a two-digit number comparison task in an online setting, we replicated previous effects, including the distance effect, the unit-decade compatibility effect, and the effect of cognitive control on the adaptation to filler items, in a large-scale study in 452 adults. Additionally, we observed that the most influential individual differences were participants' first language, time spent playing computer games and gender, followed by reported alcohol consumption, age and mathematical ability. Participants who used a first language with a left-to-right reading/writing direction were faster than those who read and wrote in the right-to-left direction. Reported playing time for computer games was correlated with faster reaction times. Female participants showed slower reaction times and a larger unit-decade compatibility effect than male participants. Participants who reported never consuming alcohol showed overall slower response times than others. Older participants were slower, but more accurate. Finally, higher grades in mathematics were associated with faster reaction times. We conclude that typical experiments on numerical cognition that employ a keyboard as an input device can also be run in an online setting. Moreover, while individual differences have no influence on domain-specific magnitude processing-apart from age, which increases the decade distance effect-they generally influence performance on a two-digit number comparison task.

  4. Laser Detection of Nanoparticles In the Environment

    EPA Science Inventory

    The United States Environmental Protection Agency (EPA) is charged by Congress to protect the nation’s natural resources. Under the mandate of national environmental laws, the EPA strives to formulate and implement actions leading to a compatible balance between human activities ...

  5. 36 CFR 12.2 - Purpose of National Cemeteries.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... United States. Such areas are protected, managed and administered as suitable and dignified burial grounds and as significant cultural resources. As such, the authorization of activities that take place in... compatible with maintaining the solemn commemorative and historic character of these areas. ...

  6. 36 CFR 12.2 - Purpose of National Cemeteries.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... United States. Such areas are protected, managed and administered as suitable and dignified burial grounds and as significant cultural resources. As such, the authorization of activities that take place in... compatible with maintaining the solemn commemorative and historic character of these areas. ...

  7. 21 CFR 606.160 - Records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... blood and red blood cells during storage and immediately before distribution. (iii) Storage temperature... GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Records and Reports § 606.160 Records. (a)(1..., processing, compatibility testing, storage and distribution of each unit of blood and blood components so...

  8. 21 CFR 606.160 - Records.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... blood and red blood cells during storage and immediately before distribution. (iii) Storage temperature... GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Records and Reports § 606.160 Records. (a)(1..., processing, compatibility testing, storage and distribution of each unit of blood and blood components so...

  9. 21 CFR 606.160 - Records.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... blood and red blood cells during storage and immediately before distribution. (iii) Storage temperature... GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Records and Reports § 606.160 Records. (a)(1..., processing, compatibility testing, storage and distribution of each unit of blood and blood components so...

  10. 21 CFR 606.160 - Records.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... blood and red blood cells during storage and immediately before distribution. (iii) Storage temperature... GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Records and Reports § 606.160 Records. (a)(1..., processing, compatibility testing, storage and distribution of each unit of blood and blood components so...

  11. 21 CFR 606.160 - Records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... blood and red blood cells during storage and immediately before distribution. (iii) Storage temperature... GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Records and Reports § 606.160 Records. (a)(1..., processing, compatibility testing, storage and distribution of each unit of blood and blood components so...

  12. Solar energy development impacts on land cover change and protected areas.

    PubMed

    Hernandez, Rebecca R; Hoffacker, Madison K; Murphy-Mariscal, Michelle L; Wu, Grace C; Allen, Michael F

    2015-11-03

    Decisions determining the use of land for energy are of exigent concern as land scarcity, the need for ecosystem services, and demands for energy generation have concomitantly increased globally. Utility-scale solar energy (USSE) [i.e., ≥ 1 megawatt (MW)] development requires large quantities of space and land; however, studies quantifying the effect of USSE on land cover change and protected areas are limited. We assessed siting impacts of >160 USSE installations by technology type [photovoltaic (PV) vs. concentrating solar power (CSP)], area (in square kilometers), and capacity (in MW) within the global solar hot spot of the state of California (United States). Additionally, we used the Carnegie Energy and Environmental Compatibility model, a multiple criteria model, to quantify each installation according to environmental and technical compatibility. Last, we evaluated installations according to their proximity to protected areas, including inventoried roadless areas, endangered and threatened species habitat, and federally protected areas. We found the plurality of USSE (6,995 MW) in California is sited in shrublands and scrublands, comprising 375 km(2) of land cover change. Twenty-eight percent of USSE installations are located in croplands and pastures, comprising 155 km(2) of change. Less than 15% of USSE installations are sited in "Compatible" areas. The majority of "Incompatible" USSE power plants are sited far from existing transmission infrastructure, and all USSE installations average at most 7 and 5 km from protected areas, for PV and CSP, respectively. Where energy, food, and conservation goals intersect, environmental compatibility can be achieved when resource opportunities, constraints, and trade-offs are integrated into siting decisions.

  13. A haptic unit designed for magnetic-resonance-guided biopsy.

    PubMed

    Tse, Z T H; Elhawary, H; Rea, M; Young, I; Davis, B L; Lamperth, M

    2009-02-01

    The magnetic fields present in the magnetic resonance (MR) environment impose severe constraints on any mechatronic device present in its midst, requiring alternative actuators, sensors, and materials to those conventionally used in traditional system engineering. In addition the spatial constraints of closed-bore scanners require a physical separation between the radiologist and the imaged region of the patient. This configuration produces a loss of the sense of touch from the target anatomy for the clinician, which often provides useful information. To recover the force feedback from the tissue, an MR-compatible haptic unit, designed to be integrated with a five-degrees-of-freedom mechatronic system for MR-guided prostate biopsy, has been developed which incorporates position control and force feedback to the operator. The haptic unit is designed to be located inside the scanner isocentre with the master console in the control room. MR compatibility of the device has been demonstrated, showing a negligible degradation of the signal-to-noise ratio and virtually no geometric distortion. By combining information from the position encoder and force sensor, tissue stiffness measurement along the needle trajectory is demonstrated in a lamb liver to aid diagnosis of suspected cancerous tissue.

  14. Medium-Bandgap Small-Molecule Donors Compatible with Both Fullerene and Nonfullerene Acceptors.

    PubMed

    Huo, Yong; Yan, Cenqi; Kan, Bin; Liu, Xiao-Fei; Chen, Li-Chuan; Hu, Chen-Xia; Lau, Tsz-Ki; Lu, Xinhui; Sun, Chun-Lin; Shao, Xiangfeng; Chen, Yongsheng; Zhan, Xiaowei; Zhang, Hao-Li

    2018-03-21

    Much effort has been devoted to the development of new donor materials for small-molecule organic solar cells due to their inherent advantages of well-defined molecular weight, easy purification, and good reproducibility in photovoltaic performance. Herein, we report two small-molecule donors that are compatible with both fullerene and nonfullerene acceptors. Both molecules consist of an (E)-1,2-di(thiophen-2-yl)ethane-substituted (TVT-substituted) benzo[1,2-b:4,5-b']dithiophene (BDT) as the central unit, and two rhodanine units as the terminal electron-withdrawing groups. The central units are modified with either alkyl side chains (DRBDT-TVT) or alkylthio side chains (DRBDT-STVT). Both molecules exhibit a medium bandgap with complementary absorption and proper energy level offset with typical acceptors like PC 71 BM and IDIC. The optimized devices show a decent power conversion efficiency (PCE) of 6.87% for small-molecule organic solar cells and 6.63% for nonfullerene all small-molecule organic solar cells. Our results reveal that rationally designed medium-bandgap small-molecule donors can be applied in high-performance small-molecule organic solar cells with different types of acceptors.

  15. Identification of Trans-4-Hydroxy-L-Proline as a Compatible Solute and Its Biosynthesis and Molecular Characterization in Halobacillus halophilus.

    PubMed

    Kim, Kyung Hyun; Jia, Baolei; Jeon, Che Ok

    2017-01-01

    Halobacillus halophilus , a moderately halophilic bacterium, accumulates a variety of compatible solutes including glycine betaine, glutamate, glutamine, proline, and ectoine to cope with osmotic stress. Non-targeted analysis of intracellular organic compounds using 1 H-NMR showed that a large amount of trans-4-hydroxy-L-proline (Hyp), which has not been reported as a compatible solute in H. halophilus , was accumulated in response to high NaCl salinity, suggesting that Hyp may be an important compatible solute in H. halophilus . Candidate genes encoding proline 4-hydroxylase (PH-4), which hydroxylates L-proline to generate Hyp, were retrieved from the genome of H. halophilus through domain searches based on the sequences of known PH-4 proteins. A gene, HBHAL_RS11735, which was annotated as a multidrug DMT transporter permease in GenBank, was identified as the PH-4 gene through protein expression analysis in Escherichia coli . The PH-4 gene constituted a transcriptional unit with a promoter and a rho-independent terminator, and it was distantly located from the proline biosynthetic gene cluster ( pro operon). Transcriptional analysis showed that PH-4 gene expression was NaCl concentration-dependent, and was specifically induced by chloride anion, similar to the pro operon. Accumulation of intracellular Hyp was also observed in other bacteria, suggesting that Hyp may be a widespread compatible solute in halophilic and halotolerant bacteria.

  16. Identification of Trans-4-Hydroxy-L-Proline as a Compatible Solute and Its Biosynthesis and Molecular Characterization in Halobacillus halophilus

    PubMed Central

    Kim, Kyung Hyun; Jia, Baolei; Jeon, Che Ok

    2017-01-01

    Halobacillus halophilus, a moderately halophilic bacterium, accumulates a variety of compatible solutes including glycine betaine, glutamate, glutamine, proline, and ectoine to cope with osmotic stress. Non-targeted analysis of intracellular organic compounds using 1H-NMR showed that a large amount of trans-4-hydroxy-L-proline (Hyp), which has not been reported as a compatible solute in H. halophilus, was accumulated in response to high NaCl salinity, suggesting that Hyp may be an important compatible solute in H. halophilus. Candidate genes encoding proline 4-hydroxylase (PH-4), which hydroxylates L-proline to generate Hyp, were retrieved from the genome of H. halophilus through domain searches based on the sequences of known PH-4 proteins. A gene, HBHAL_RS11735, which was annotated as a multidrug DMT transporter permease in GenBank, was identified as the PH-4 gene through protein expression analysis in Escherichia coli. The PH-4 gene constituted a transcriptional unit with a promoter and a rho-independent terminator, and it was distantly located from the proline biosynthetic gene cluster (pro operon). Transcriptional analysis showed that PH-4 gene expression was NaCl concentration-dependent, and was specifically induced by chloride anion, similar to the pro operon. Accumulation of intracellular Hyp was also observed in other bacteria, suggesting that Hyp may be a widespread compatible solute in halophilic and halotolerant bacteria. PMID:29104571

  17. Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum.

    PubMed

    Yang, Zhilai; Chen, Na; Ge, Rongjing; Qian, Hao; Wang, Jin-Hui

    2017-09-22

    A neuron sprouts an axon, and its branches to innervate many target neurons that are divergent in their functions. In order to efficiently regulate the diversified cells, the axon branches should differentiate functionally to be compatible with their target neurons, i.e., a function compatibility between presynaptic and postsynaptic partners. We have examined this hypothesis by using electrophysiological method in the cerebellum, in which the main axon of Purkinje cell projected to deep nucleus cells and the recurrent axons innervated the adjacent Purkinje cells. The fidelity of spike propagation is superior in the recurrent branches than the main axon. The capabilities of encoding spikes and processing GABAergic inputs are advanced in Purkinje cells versus deep nucleus cells. The functional differences among Purkinje's axonal branches and their postsynaptic neurons are preset by the variable dynamics of their voltage-gated sodium channels. In addition, activity strengths between presynaptic and postsynaptic partners are proportionally correlated, i.e., active axonal branches innervate active target neurons, or vice versa. The physiological impact of the functional compatibility is to make the neurons in their circuits to be activated appropriately. In conclusion, each cerebellar Purkinje cell sprouts the differentiated axon branches to be compatible with the diversified target cells in their functions, in order to construct the homeostatic and efficient units for their coordinated activity in neural circuits.

  18. Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum

    PubMed Central

    Qian, Hao; Wang, Jin-Hui

    2017-01-01

    A neuron sprouts an axon, and its branches to innervate many target neurons that are divergent in their functions. In order to efficiently regulate the diversified cells, the axon branches should differentiate functionally to be compatible with their target neurons, i.e., a function compatibility between presynaptic and postsynaptic partners. We have examined this hypothesis by using electrophysiological method in the cerebellum, in which the main axon of Purkinje cell projected to deep nucleus cells and the recurrent axons innervated the adjacent Purkinje cells. The fidelity of spike propagation is superior in the recurrent branches than the main axon. The capabilities of encoding spikes and processing GABAergic inputs are advanced in Purkinje cells versus deep nucleus cells. The functional differences among Purkinje's axonal branches and their postsynaptic neurons are preset by the variable dynamics of their voltage-gated sodium channels. In addition, activity strengths between presynaptic and postsynaptic partners are proportionally correlated, i.e., active axonal branches innervate active target neurons, or vice versa. The physiological impact of the functional compatibility is to make the neurons in their circuits to be activated appropriately. In conclusion, each cerebellar Purkinje cell sprouts the differentiated axon branches to be compatible with the diversified target cells in their functions, in order to construct the homeostatic and efficient units for their coordinated activity in neural circuits. PMID:29069799

  19. Instrumentation for fast-scan cyclic voltammetry combined with electrophysiology for behavioral experiments in freely moving animals

    NASA Astrophysics Data System (ADS)

    Takmakov, Pavel; McKinney, Collin J.; Carelli, Regina M.; Wightman, R. Mark

    2011-07-01

    Fast-scan cyclic voltammetry is a unique technique for sampling dopamine concentration in the brain of rodents in vivo in real time. The combination of in vivo voltammetry with single-unit electrophysiological recording from the same microelectrode has proved to be useful in studying the relationship between animal behavior, dopamine release and unit activity. The instrumentation for these experiments described here has two unique features. First, a 2-electrode arrangement implemented for voltammetric measurements with the grounded reference electrode allows compatibility with electrophysiological measurements, iontophoresis, and multielectrode measurements. Second, we use miniaturized electronic components in the design of a small headstage that can be fixed on the rat's head and used in freely moving animals.

  20. The design and fabrication of a prototype trash compacting unit. [for long duration space missions

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A prototype trash compactor, that is compatible with the anticipated requirements of future long-term space missions, is described. Preliminary problem definition studies were conducted to identify typical types and quantities of waste materials to be expected from a typical mission. Bench-scale compaction tests were then conducted on typical waste materials to determine force/compaction curves. These data were used to design a boilerplate compactor that was fabricated to prove the feasibility of the basic design concept. A final design was then prepared from which the deliverable unit was fabricated. Design concepts are presented for suggested further development of the compactor, including a version that is capable of handling wet biodegradable wastes.

  1. Lead recycling in the United States in 1998

    USGS Publications Warehouse

    Smith, Gerald R.

    2002-01-01

    This materials flow study includes a description of lead supply and demand factors for the United States to illustrate the extent of lead recycling and to identify recycling trends. Understanding the system of materials flow from source to ultimate disposition can assist in improving the management of the use of natural resources in a manner that is compatible with sound environmental practices. The quantity of lead recycled in 1998, as a percentage of apparent lead supply, was estimated to be about 63 percent, and recycling efficiency, to be 95 percent. Of the total lead consumed in products for the U.S. market in 1998, an estimated 10 percent was consumed in products in which the lead was not readily recyclable.

  2. Instrumentation for fast-scan cyclic voltammetry combined with electrophysiology for behavioral experiments in freely moving animals

    PubMed Central

    Takmakov, Pavel; McKinney, Collin J.; Carelli, Regina M.; Wightman, R. Mark

    2011-01-01

    Fast-scan cyclic voltammetry is a unique technique for sampling dopamine concentration in the brain of rodents in vivo in real time. The combination of in vivo voltammetry with single-unit electrophysiological recording from the same microelectrode has proved to be useful in studying the relationship between animal behavior, dopamine release and unit activity. The instrumentation for these experiments described here has two unique features. First, a 2-electrode arrangement implemented for voltammetric measurements with the grounded reference electrode allows compatibility with electrophysiological measurements, iontophoresis, and multielectrode measurements. Second, we use miniaturized electronic components in the design of a small headstage that can be fixed on the rat's head and used in freely moving animals. PMID:21806203

  3. Geostationary platform systems concepts definition study. Volume 2: Technical, book 1

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The initial selection and definition of operational geostationary platform concepts is discussed. Candidate geostationary platform missions and payloads were identified from COMSAT, Aerospace, and NASA studies. These missions and payloads were cataloged; classified with to communications, military, or scientific uses; screened for application and compatibility with geostationary platforms; and analyzed to identify platform requirements. Two platform locations were then selected (Western Hemisphere - 110 deg W, and Atlantic - 15 deg W), and payloads allocated based on nominal and high traffic models. Trade studies were performed leading to recommendation of selected concepts. Of 30 Orbit Transfer Vehicle (0TV) configuration and operating mode options identified, 18 viable candidates compatible with the operational geostationary platform missions were selected for analysis. Each was considered using four platform operational modes - 8 or 16 year life, and serviced or nonserviced, providing a total of 72 OTV/platform-mode options. For final trade study concept selection, a cost program was developed considering payload and platform costs and weight; transportation unit and total costs for the shuttle and OTV; and operational costs such as assembly or construction time, mating time, and loiter time. Servicing costs were added for final analysis and recommended selection.

  4. SEROLOGICAL RESPONSES TO CRYPTOSPORIDIUM ANTIGENS AMONG USERS OF SURFACE VERSUS UNDERGROUND DRINKING WATER SOURCES

    EPA Science Inventory

    Cryptosporidium oocysts have been detected in source and treated drinking waters in the United States and elsewhere. Enhanced enteric disease surveillance, initiated following detection of oocysts, has not often detected elevated rates of infection or of symptoms compatible with...

  5. Approach to a case of multiple irregular red cell antibodies in a liver transplant recipient: Need for developing competence

    PubMed Central

    Dara, Ravi C.; Tiwari, Aseem K.; Pandey, Prashant; Arora, Dinesh

    2015-01-01

    Liver transplant procedure acts as a challenge for transfusion services in terms of specialized blood components, serologic problems, and immunologic effects of transfusion. Red cell alloimmunization in patients awaiting a liver transplant complicate the process by undue delay or unavailability of compatible red blood cell units. Compatible blood units can be provided by well-equipped immunohematology laboratory, which has expertise in resolving these serological problems. This report illustrates resolution of a case with multiple alloantibodies using standard techniques, particularly rare antisera. Our case re-emphasizes the need for universal antibody screening in all patients as part of pretransfusion testing, which helps to identify atypical antibodies and plan for appropriate transfusion support well in time. We recommend that the centers, especially the ones that perform complex procedures like solid organ transplants and hematological transplants should have the necessary immunohematological reagents including rare antisera to resolve complex cases of multiple antibodies as illustrated in this case. PMID:25722585

  6. Autotransporter-based cell surface display in Gram-negative bacteria.

    PubMed

    Nicolay, Toon; Vanderleyden, Jos; Spaepen, Stijn

    2015-02-01

    Cell surface display of proteins can be used for several biotechnological applications such as the screening of protein libraries, whole cell biocatalysis and live vaccine development. Amongst all secretion systems and surface appendages of Gram-negative bacteria, the autotransporter secretion pathway holds great potential for surface display because of its modular structure and apparent simplicity. Autotransporters are polypeptides made up of an N-terminal signal peptide, a secreted or surface-displayed passenger domain and a membrane-anchored C-terminal translocation unit. Genetic replacement of the passenger domain allows for the surface display of heterologous passengers. An autotransporter-based surface expression module essentially consists of an application-dependent promoter system, a signal peptide, a passenger domain of interest and the autotransporter translocation unit. The passenger domain needs to be compatible with surface translocation although till now no general rules have been determined to test this compatibility. The autotransporter technology for surface display of heterologous passenger domains is critically discussed for various applications.

  7. Producing Information for Corine Database by Using Classification Method: a Case Study of Sazlidere Basin, Istanbul

    NASA Astrophysics Data System (ADS)

    Sarıyılmaz, F. B.; Musaoğlu, N.; Uluğtekin, N.

    2017-11-01

    The Sazlidere Basin is located on the European side of Istanbul within the borders of Arnavutkoy and Basaksehir districts. The total area of the basin, which is largely located within the province of Arnavutkoy, is approximately 177 km2. The Sazlidere Basin is faced with intense urbanization pressures and land use / cover change due to the Northern Marmara Motorway, 3rd airport and Channel Istanbul Projects, which are planned to be realized in the Arnavutkoy region. Due to the mentioned projects, intense land use /cover changes occur in the basin. In this study, 2000 and 2012 dated LANDSAT images were supervised classified based on CORINE Land Cover first level to determine the land use/cover classes. As a result, four information classes were identified. These classes are water bodies, forest and semi-natural areas, agricultural areas and artificial surfaces. Accuracy analysis of the images were performed following the classification process. The supervised classified images that have the smallest mapping units 0.09 ha and 0.64 ha were generalized to be compatible with the CORINE Land Cover data. The image pixels have been rearranged by using the thematic pixel aggregation method as the smallest mapping unit is 25 ha. These results were compared with CORINE Land Cover 2000 and CORINE Land Cover 2012, which were obtained by digitizing land cover and land use classes on satellite images. It has been determined that the compared results are compatible with each other in terms of quality and quantity.

  8. The Risk of Transplant Failure With HLA Mismatch in First Adult Kidney Allografts From Deceased Donors.

    PubMed

    Williams, Robert C; Opelz, Gerhard; McGarvey, Chelsea J; Weil, E Jennifer; Chakkera, Harini A

    2016-05-01

    Since the beginning of the technology, there has been active debate about the role of human leucocyte antigen (HLA) matching in kidney allograft survival. Recent studies have reported diminishing importance of HLA matching, which have, in turn, been challenged by reports that suggest the continuing importance of these loci. Given the controversies, we examined the effect of HLA compatibility on kidney allograft survival by studying all first adult kidney transplants in the United States from a deceased donor. Using the United Network for Organ Sharing data, we identified first deceased donor kidney transplants between October 1, 1987, and December 31, 2013. Recipients were classified by their number of HLA mismatches. Cox multivariate regression analyses adjusting for recipient and donor transplant characteristics were performed to determine the impact of HLA compatibility on kidney allograft survival. Study cohort included 189 141 first adult kidney alone transplants, with a total of 994 558 years of kidney allograft follow-up time. Analyses adjusted for recipient and donor characteristics demonstrated a 13% higher risk (hazard ratio, 1.13; 95% confidence interval, 1.06-1.21) with 1 mismatch and a 64% higher risk (hazard ratio, 1.64, 95% confidence interval, 1.56-1.73) with 6 mismatches. Dividing the mismatch categories into 27 ordered permutations, and testing their 57 within mismatch category differences, demonstrated that all but 1 were equal, independent of locus. A significant linear relationship of hazard ratios was associated with HLA mismatch and affects allograft survival even during the recent periods of increasing success in renal transplantation.

  9. Design of BLDCM emulator for transmission control units

    NASA Astrophysics Data System (ADS)

    Liu, Chang; He, Yongyi; Zhang, Bodong

    2018-04-01

    According to the testing requirements of the transmission control unit, a brushless DC motor emulating system is designed based on motor simulation and power hardware-in-the-loop. The discrete motor model is established and a real-time numerical method is designed to solve the motor states. The motor emulator directly interacts with power stage of the transmission control unit using a power-efficient circuit topology and is compatible with sensor-less control. Experiments on a laboratory prototype help to verify that the system can emulate the real motor currents and voltages whenever the motor is starting up or suddenly loaded.

  10. Trinary arithmetic and logic unit (TALU) using savart plate and spatial light modulator (SLM) suitable for optical computation in multivalued logic

    NASA Astrophysics Data System (ADS)

    Ghosh, Amal K.; Bhattacharya, Animesh; Raul, Moumita; Basuray, Amitabha

    2012-07-01

    Arithmetic logic unit (ALU) is the most important unit in any computing system. Optical computing is becoming popular day-by-day because of its ultrahigh processing speed and huge data handling capability. Obviously for the fast processing we need the optical TALU compatible with the multivalued logic. In this regard we are communicating the trinary arithmetic and logic unit (TALU) in modified trinary number (MTN) system, which is suitable for the optical computation and other applications in multivalued logic system. Here the savart plate and spatial light modulator (SLM) based optoelectronic circuits have been used to exploit the optical tree architecture (OTA) in optical interconnection network.

  11. Constrained tri-sphere kinematic positioning system

    DOEpatents

    Viola, Robert J

    2010-12-14

    A scalable and adaptable, six-degree-of-freedom, kinematic positioning system is described. The system can position objects supported on top of, or suspended from, jacks comprising constrained joints. The system is compatible with extreme low temperature or high vacuum environments. When constant adjustment is not required a removable motor unit is available.

  12. Non Contacting Evaluation of Strains and Cracking Using Optical and Infrared Imaging Techniques

    DTIC Science & Technology

    1988-08-22

    Compatible Zenith Z-386 microcomputer with plotter II. 3-D Motion Measurinq System 1. Complete OPTOTRAK three dimensional digitizing system. System includes...acquisition unit - 16 single ended analog input channels 3. Data Analysis Package software (KINEPLOT) 4. Extra OPTOTRAK Camera (max 224 per system

  13. Interoperability Is the Foundation for Successful Internet Telephony.

    ERIC Educational Resources Information Center

    Fromm, Larry

    1997-01-01

    More than 40 leading computer and telephony companies have united to lead the charge toward open standards and universal interoperability for Internet telephony products. The voice of IP Forum (VoIP) is working to define technical guidelines for two-party, real-time communications over IP networks, including provisions for compatibility with…

  14. 32 CFR 211.9 - Mitigation Options.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Mitigation Options. 211.9 Section 211.9 National... MISSION COMPATIBILITY EVALUATION PROCESS Project Evaluation Procedures § 211.9 Mitigation Options. (a) In discussing mitigation to avoid an unacceptable risk to the national security of the United States, the DoD...

  15. 32 CFR 211.9 - Mitigation options.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Mitigation options. 211.9 Section 211.9 National... MISSION COMPATIBILITY EVALUATION PROCESS Project Evaluation Procedures § 211.9 Mitigation options. (a) In discussing mitigation to avoid an unacceptable risk to the national security of the United States, the DoD...

  16. 32 CFR 211.9 - Mitigation Options.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Mitigation Options. 211.9 Section 211.9 National... MISSION COMPATIBILITY EVALUATION PROCESS Project Evaluation Procedures § 211.9 Mitigation Options. (a) In discussing mitigation to avoid an unacceptable risk to the national security of the United States, the DoD...

  17. 40 CFR 60.5235 - What reports must I submit?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert_tool.html/) or other compatible... Existing Sewage Sludge Incineration Units Model Rule-Recordkeeping and Reporting § 60.5235 What reports... reporting period specified in paragraph (c)(3) of this section. You must submit your first annual compliance...

  18. Statement of Work for Volpe Center Execution of DOT GPS Adjacent Band Compatibility Testing Program

    DOT National Transportation Integrated Search

    2015-01-01

    DOT should cause GPS firms to produce to Volpe for testing the following devices: The ten (10) top selling device models in the United States for the calendar year 2014. In addition GPS manufacturers will provide Volpe with the identities of their to...

  19. 36 CFR 13.142 - Transfer.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; and (d) The continued use and occupancy will not adversely impact soils, vegetation, water or wildlife... PARK SYSTEM UNITS IN ALASKA Cabins Cabin Use-Leases Or Permits in Effect on December 2, 1980 § 13.142...) The continued use is appropriate and compatible with the values and purposes of the park area; (b) The...

  20. Marshall Space Flight Center Electromagnetic Compatibility Design and Interference Control (MEDIC) handbook

    NASA Astrophysics Data System (ADS)

    Clark, T. L.; McCollum, M. B.; Trout, D. H.; Javor, K.

    1995-06-01

    The purpose of the MEDIC Handbook is to provide practical and helpful information in the design of electrical equipment for electromagnetic compatibility (EMS). Included is the definition of electromagnetic interference (EMI) terms and units as well as an explanation of the basic EMI interactions. An overview of typical NASA EMI test requirements and associated test setups is given. General design techniques to minimize the risk of EMI and EMI suppression techniques at the board and equipment interface levels are presented. The Handbook contains specific EMI test compliance design techniques and retrofit fixes for noncompliant equipment. Also presented are special tests that are useful in the design process or in instances of specification noncompliance.

  1. Marshall Space Flight Center Electromagnetic Compatibility Design and Interference Control (MEDIC) handbook

    NASA Technical Reports Server (NTRS)

    Clark, T. L.; Mccollum, M. B.; Trout, D. H.; Javor, K.

    1995-01-01

    The purpose of the MEDIC Handbook is to provide practical and helpful information in the design of electrical equipment for electromagnetic compatibility (EMS). Included is the definition of electromagnetic interference (EMI) terms and units as well as an explanation of the basic EMI interactions. An overview of typical NASA EMI test requirements and associated test setups is given. General design techniques to minimize the risk of EMI and EMI suppression techniques at the board and equipment interface levels are presented. The Handbook contains specific EMI test compliance design techniques and retrofit fixes for noncompliant equipment. Also presented are special tests that are useful in the design process or in instances of specification noncompliance.

  2. 20 kHz main inverter unit. [for space station power supplies

    NASA Technical Reports Server (NTRS)

    Hussey, S.

    1989-01-01

    A proof-of-concept main inverter unit has demonstrated the operation of a pulse-width-modulated parallel resonant power stage topology as a 20-kHz ac power source driver, showing simple output regulation, parallel operation, power sharing and short-circuit operation. The use of a two-stage dc input filter controls the electromagnetic compatibility (EMC) characteristics of the dc power bus, and the use of an ac harmonic trap controls the EMC characteristics of the 20-kHz ac power bus.

  3. An Open-Source Hardware and Software System for Acquisition and Real-Time Processing of Electrophysiology during High Field MRI

    PubMed Central

    Purdon, Patrick L.; Millan, Hernan; Fuller, Peter L.; Bonmassar, Giorgio

    2008-01-01

    Simultaneous recording of electrophysiology and functional magnetic resonance imaging (fMRI) is a technique of growing importance in neuroscience. Rapidly evolving clinical and scientific requirements have created a need for hardware and software that can be customized for specific applications. Hardware may require customization to enable a variety of recording types (e.g., electroencephalogram, local field potentials, or multi-unit activity) while meeting the stringent and costly requirements of MRI safety and compatibility. Real-time signal processing tools are an enabling technology for studies of learning, attention, sleep, epilepsy, neurofeedback, and neuropharmacology, yet real-time signal processing tools are difficult to develop. We describe an open source system for simultaneous electrophysiology and fMRI featuring low-noise (< 0.6 uV p-p input noise), electromagnetic compatibility for MRI (tested up to 7 Tesla), and user-programmable real-time signal processing. The hardware distribution provides the complete specifications required to build an MRI-compatible electrophysiological data acquisition system, including circuit schematics, print circuit board (PCB) layouts, Gerber files for PCB fabrication and robotic assembly, a bill of materials with part numbers, data sheets, and vendor information, and test procedures. The software facilitates rapid implementation of real-time signal processing algorithms. This system has used in human EEG/fMRI studies at 3 and 7 Tesla examining the auditory system, visual system, sleep physiology, and anesthesia, as well as in intracranial electrophysiological studies of the non-human primate visual system during 3 Tesla fMRI, and in human hyperbaric physiology studies at depths of up to 300 feet below sea level. PMID:18761038

  4. An open-source hardware and software system for acquisition and real-time processing of electrophysiology during high field MRI.

    PubMed

    Purdon, Patrick L; Millan, Hernan; Fuller, Peter L; Bonmassar, Giorgio

    2008-11-15

    Simultaneous recording of electrophysiology and functional magnetic resonance imaging (fMRI) is a technique of growing importance in neuroscience. Rapidly evolving clinical and scientific requirements have created a need for hardware and software that can be customized for specific applications. Hardware may require customization to enable a variety of recording types (e.g., electroencephalogram, local field potentials, or multi-unit activity) while meeting the stringent and costly requirements of MRI safety and compatibility. Real-time signal processing tools are an enabling technology for studies of learning, attention, sleep, epilepsy, neurofeedback, and neuropharmacology, yet real-time signal processing tools are difficult to develop. We describe an open-source system for simultaneous electrophysiology and fMRI featuring low-noise (<0.6microV p-p input noise), electromagnetic compatibility for MRI (tested up to 7T), and user-programmable real-time signal processing. The hardware distribution provides the complete specifications required to build an MRI-compatible electrophysiological data acquisition system, including circuit schematics, print circuit board (PCB) layouts, Gerber files for PCB fabrication and robotic assembly, a bill of materials with part numbers, data sheets, and vendor information, and test procedures. The software facilitates rapid implementation of real-time signal processing algorithms. This system has been used in human EEG/fMRI studies at 3 and 7T examining the auditory system, visual system, sleep physiology, and anesthesia, as well as in intracranial electrophysiological studies of the non-human primate visual system during 3T fMRI, and in human hyperbaric physiology studies at depths of up to 300 feet below sea level.

  5. Physical compatibility of plazomicin with select i.v. drugs during simulated Y-site administration.

    PubMed

    Asempa, Tomefa E; Avery, Lindsay M; Kidd, James M; Kuti, Joseph L; Nicolau, David P

    2018-06-12

    The results of a study to determine the physical compatibility of plazomicin sulfate solution during simulated Y-site administration with 92 i.v. drugs are reported. Plazomicin injection solution (500 mg/10 mL) was diluted in 0.9% sodium chloride or 5% dextrose for injection to a final volume of 50 mL (final plazomicin concentration, 24 mg/mL), consistent with a 15-mg/kg dose administered to an 80-kg patient (i.e., 1,200 mg). All other i.v. drugs were reconstituted according to manufacturers' recommendations and diluted with 0.9% sodium chloride or 5% dextrose for injection to the upper range of concentrations used clinically. Y-site conditions were simulated by mixing 5 mL of plazomicin solution with 5 mL of tested drug solutions in a 1:1 ratio. Solutions were assessed for visual (via color and Tyndall beam testing), turbidity (using a laboratory-grade turbidimeter), and pH changes over a 60-minute observation period. Incompatibility was defined a priori as precipitation, color change, a positive Tyndall test, or a turbidity change of ≥0.5 nephelometric turbidity units at any time during the 60-minute observation period. Plazomicin was physically compatible with 79 of the 92 drugs tested. Determinations of physical incompatibility with plazomicin were made for 13 drugs: albumin, amiodarone, amphotericin B deoxycholate, anidulafungin, calcium chloride, daptomycin, esomeprazole, heparin, levofloxacin, methylprednisolone, micafungin, phenytoin, and propofol, CONCLUSION: Plazomicin at a concentration of 24 mg/mL was physically compatible with 85% of the drugs tested, including 31 of 36 antimicrobial agents. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  6. Compatibility of the Parasitoid Wasp Spalangia endius (Hymenoptera: Pteromalidae) and Insecticides against Musca domestica (Diptera: Muscidae) as Evaluated by a New Index.

    PubMed

    Burgess, Edwin R; King, B H

    2015-06-01

    Various insecticides for the control of the house fly Musca domestica L. were tested for compatibility with a biological control agent, the pupal parasitoid Spalangia endius Walker. Bioassays used the mode in which each organism was expected to be harmed by the insecticides, a surface contact bioassay for S. endius and a feeding bioassay for M. domestica. A Pesticide Compatibility Index (PCI) was created that allows comparison of LC50 values when the mode of exposure to a pesticide differs. First LC50 values were converted into units of prescribed dosages (LPR=LC50-to-prescribed dosage ratio). This study used dosages from labels of granular baits. PCI is the ratio of LPRbiological control agent to LPRpest. For these PCI values, order of compatibility with S. endius was spinosad>thiamethoxam>inotefuran>methomyl>imidacloprid. That spinosad was better than imidacloprid or methomyl, both for parasitoid survival and for killing flies, is consistent with conclusions from the LC50 values. Permethrin and nitenpyram were also tested, but their PCIs were not calculated. Permethrin is prescribed as a contact insecticide against flies rather than being consumed as a bait, and nitenpyram has not been formulated as a fly insecticide. Compared with the other insecticides in terms of LC50 values, permethrin was moderately toxic to S. endius but one of the most toxic for M. domestica, whereas nitenpyram was least toxic for both S. endius and the flies. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  7. Design and operation experience of 230 MWe CFB boilers at Turow power plant in Poland

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nowak, W.; Bis, Z.; Laskawiec, J.

    The Power Station Turow is located in Bogatynia, Poland, and has operated 10 pulverized coal units each of 200 MW. The plant provided 2000 MW at the lowest cost per kWh in Poland. The Turow units have approached and in some cases already gone beyond their 25--30 year's design life. To meet Poland's new environmental standards, which are now compatible with the EU, Turow decided to replace and upgrade six units (No. 1 to 6) from 200 MW to 230 MW units and remove one unit No. 7. Units No. 8, 9 and 10 were equipped with dry sorbent desulfurizationmore » technology. Units No. 1 and 2 have been replaced with new clean coal circulating fluidized bed technology. The Power Station Turow with six CFB units is to be the largest in the world power station based on fluidized bed technology.« less

  8. Design study of wind turbines 50 kW to 3000 kW for electric utility applications. Volume 1: Summary report

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Wind turbine configurations that would lead to generation of electrical power in a cost effective manner were considered. All possible overall system configurationss, operating modes, and sybsystem concepts were evaluated for both technical feasibility and compatibility with utility networks, as well as for economic attractiveness. A design optimization computer code was developed to determine the cost sensitivity of the various design features, and thus establish the configuration and design conditions that would minimize the generated energy costs. The preliminary designs of both a 500 kW unit and a 1500 kW unit operating in a 12 mph and 18 mph median wind speed respectively, were developed. The rationale employed and the key findings are summarized.

  9. The work compatibility improvement framework: an assessment of the worker-work environment interaction in the manufacturing sector.

    PubMed

    Genaidy, Ash M; Rinder, Magda M; A-Rehim, Amal D

    2008-08-01

    The manufacturing sector in the US is challenged by high health care costs and shortage of qualified workers, which are largely attributed to the degree of fit between the worker and work environment. In this regard, a healthy worker-work environment interface is a necessary and sufficient condition for the containment of health care costs and the retaining/attraction of highly qualified knowledge workers and should be based on the principles of optimum physical, cognitive and emotional health for the workers. In prior research, the Work Compatibility Improvement Framework (WCIF) was introduced as a vehicle to address these issues and was defined as the identification, improvement and maintenance of the well-being characteristics of the workforce and its interaction with the work environment through the application of engineering, medicine, management and human sciences methodologies, technologies and best practices. This paper advances WCIF by examining its applications in manufacturing with regard to the evaluation of working conditions impacting musculoskeletal/stress outcome measures. A study was conducted in a machining department of a bag packaging manufacturer in the Midwest of the United States. The work tasks were planned and executed with regard to the following aims: (1) to compute work compatibility as a function of work demands and energisers; (2) to establish whether the prevalence of musculoskeletal/stress disorders increases with a decrease in the quality of worker-work environment interface in terms of work compatibility level and other work factors such as shift and job category. A major finding is that a 'poor' work environment (a function of all work domains) results in musculoskeletal/stress disorders that are 105% and 67% higher than those for a 'good' work environment. The evening shift exhibited the poorest compatibility followed by the night shift relative to the day shift. Application of the work compatibility approach demonstrated the detection of non-added value work. It is essential to evaluate the various domains of worker-work environment interface to uncover the root causes that tend to sub-optimise the physical/cognitive/emotional health of the workforce. The WCIF was used to uncover the non-value added effort in the work process. These findings will have major implications for developing and implementing customised design interventions with the aim to maximise the benefit and reduce the cost of employees in a manufacturing enterprise. The study findings suggest that the WCIF should be pursued as a potential strategic tool for optimising human performance in an enterprise to create healthy workplaces.

  10. Peripatetic plague.

    PubMed

    Mann, J M; Schmid, G P; Stoesz, P A; Skinner, M D; Kaufmann, A F

    1982-01-01

    Cases of plague continue to occur in various parts of the world, including the western United States, where plague is endemic among the wild rodent population. In 1980, a case of plague acquired in New Mexico and hospitalized in Nebraska illustrated the problem of plague occurring in persons traveling from the state in which they become infected to another state. Nine cases of plague in travelers were identified among the 166 cases of plague reported in the United States from 1950 to 1980. Physicians should be aware of natural plague foci in the western United States and should obtain a travel history from patients with an illness clinically compatible with plague.

  11. Red cell storage in E-Sol 5 and Adsol additive solutions: paired comparison using mixed and non-mixed study designs.

    PubMed

    Radwanski, K; Thill, M; Min, K

    2014-05-01

    If transfusion of older stored red cells is found to negatively affect clinical outcome, one possible alternative to shortened outdate is the use of new additive solutions (AS) that ameliorate the storage lesion. Erythro-Sol (E-Sol), a previously developed next-generation AS, has been reformulated into E-Sol 5, which is compatible with current anticoagulants and AS volumes. The effect of E-Sol 5 on red cells during storage compared to current AS has not been reported. Paired, ABO-matched whole-blood units were collected into CPD anticoagulant, pooled, split and processed into plasma and red cell units with either 110 ml of Adsol or 105 ml of E-Sol 5 within 8 h of collection. In Study 1, paired units in E-Sol 5 and Adsol were sampled on Day 0 and every 7 days up to Day 42 (n = 10). In Study 2, paired units in E-Sol 5 and Adsol were sampled only on Day 0 and Day 42 (n = 10). In Study 1, 2,3 DPG levels were maintained until Day 28 in E-Sol 5 units and Day 14 in Adsol units. ATP levels were higher in E-Sol 5 units until Day 21, after which they were comparable between the two groups. In both studies, metabolic activity was greater in E-Sol 5 units with respect to glucose consumption and lactate production. Morphology scores were higher, and haemolysis and microparticles generated were lower in E-Sol 5 vs. Adsol units. Weekly mixing of units lowered haemolysis and microparticle levels and increased potassium content on Day 42 in both additive solutions. Regardless of whether units are mixed weekly or are stored non-mixed, E-Sol 5 slows the progression of the red cell storage lesion and improves the overall in vitro quality of RBC throughout storage. © 2013 International Society of Blood Transfusion.

  12. 76 FR 34962 - Project Waiver of Section 1605 (Buy American Requirements) of the American Recovery and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... compatible and adaptable to the space restrictions created by the existing facility. DATES: June 15, 2011... space for HVAC equipment and the associated accessories. The project requires a very high-efficiency... USDA's knowledge, there is no HVAC equipment manufactured in the United States that meets the County's...

  13. 76 FR 3307 - Hazardous Materials: Harmonization With the United Nations Recommendations, International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ... Compatibility Group S indicates that hazardous effects from accidental functioning are limited to the extent the... package is capable of containing any hazardous effects in the event of an accidental functioning of its... demonstrate that any hazardous effects are confined within a package. In the ANPRM, we invited commenters to...

  14. The Area Resource File: ARF. A Manpower Planning and Research Tool.

    ERIC Educational Resources Information Center

    Applied Management Sciences, Inc., Silver Spring, MD.

    This publication describes the Area Resource File (ARF), a computer-based, county-specific health information system with broad analytical capabilities which utilizes manpower and manpower-related data that are available on a compatible basis for all counties in the United States, and which was developed to summarize statistics from many disparate…

  15. 40 CFR 60.4915 - What reports must I submit?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert_tool.html/) or other compatible... Sludge Incineration Units Recordkeeping and Reporting § 60.4915 What reports must I submit? You must... reporting period specified in paragraph (d)(3) of this section. You must submit your first annual compliance...

  16. 40 CFR 60.4915 - What reports must I submit?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert_tool.html/) or other compatible... Sludge Incineration Units Recordkeeping and Reporting § 60.4915 What reports must I submit? You must... reporting period specified in paragraph (d)(3) of this section. You must submit your first annual compliance...

  17. Design, development and evaluation of Stanford/Ames Extra-Vehicular Activity (EVA) prehensors

    NASA Technical Reports Server (NTRS)

    Leifer, Larry J.; Jameson, J.; Leblanc, M.; Wilson, D.; Sabelman, E.; Schwandt, D.

    1987-01-01

    A summary is given of progress to date on work proposed in 1983 and continued in 1985, including design iterations on three different types of manually powered prehensors, construction of functional mockups of each and culminating in detailed drawings and specifications for suit-compatible sealed units for testing under realistic conditions.

  18. Use of quantitative traits to assess aggressiveness of Phakopsora pachyrhizi isolates from Nigeria and the United States

    USDA-ARS?s Scientific Manuscript database

    Soybean rust, caused by Phakopsora pachyrhizi, is one of the most important foliar diseases of soybean worldwide. The soybean-P. pachyrhizi interaction is often complex because of the genetic variability in host and pathogen genotypes. In a compatible reaction, soybean genotypes produce tan colored ...

  19. Operational Loopwheel Suspension System for Mars Rover Demonstration Model

    NASA Technical Reports Server (NTRS)

    Trautwein, W.; Robinson, G. D.

    1978-01-01

    The loopwheel (or elastic loop) mobility concept, appears to be uniquely qualified to provide a high degree of mobility at low weight and stowage requirements for the next Mars mission now in the early planning stage. Traction elements compatible with sterilization and Mars surface environmental constraints were designed and are compatible with the rover mass, range and stowage requirements of JPL's point design Mars rover. In order to save cost, the loopwheel suspensions for the demonstration model were made of S-glass/epoxy instead of titanium, alloy specified for flight units. The load carrying fiberglass loop core is covered by a rubber tread on the outside. Reinforced rubber gear belts bonded along the inside edges provide positive engagement and transmission drive torques. A 12 Vdc drive motor with a 167:1 gear head is installed in the payload section of the hull. A chain drive transmits the motor power to the rear sprocket in the demonstration model, whereas future flight units would be directly driven by brushless hub motors within each sprocket and independent four-leg height control.

  20. Compatibility Studies of Hydrogen Peroxide and a New Hypergolic Fuel Blend

    NASA Technical Reports Server (NTRS)

    Baldridge, Jennifer; Villegas, Yvonne

    2002-01-01

    Several preliminary materials compatibility studies have been conducted to determine the practicality of a new hypergolic fuel system. Hypergolic fuel ignites spontaneously as the oxidizer decomposes and releases energy in the presence of the fuel. The bipropellant system tested consists of high-test hydrogen peroxide (HTP) and a liquid fuel blend consisting of a hydrocarbon fuel, an ignition enhancer and a transition metal catalyst. In order for further testing of the new fuel blend to take place, some basic materials compatibility and HTP decomposition studies must be accomplished. The thermal decomposition rate of HTP was tested using gas evolution and isothermal microcalorimetry (IMC). Materials were analyzed for compatibility with hydrogen peroxide including a study of the affect welding has on stainless steel elemental composition and its relation to HTP decomposition. Compatibility studies of valve materials in the fuel blend were performed to determine the corrosion resistance of the materials.

  1. An RFID-based on-lens sensor system for long-term IOP monitoring.

    PubMed

    Hsu, Shun-Hsi; Chiou, Jin-Chern; Liao, Yu-Te; Yang, Tzu-Sen; Kuei, Cheng-Kai; Wu, Tsung-Wei; Huang, Yu-Chieh

    2015-01-01

    In this paper, an RFID-based on-lens sensor system is proposed for noninvasive long-term intraocular pressure monitoring. The proposed sensor IC, fabricated in a 0.18um CMOS process, consists of capacitive sensor readout circuitry, RFID communication circuits, and digital processing units. The sensor IC is integrated with electroplating capacitive sensors and a receiving antenna on the contact lens. The sensor IC can be wirelessly powered, communicate with RFID compatible equipment, and perform IOP measurement using on-lens capacitive sensor continuously from a 2cm distance while the incident power from an RFID reader is 20 dBm. The proposed system is compatible to Gen2 RFID protocol, extending the flexibility and reducing the self-developed firmware efforts.

  2. Power processor for a 30cm ion thruster

    NASA Technical Reports Server (NTRS)

    Biess, J. J.; Inouye, L. Y.

    1974-01-01

    A thermal vacuum power processor for the NASA Lewis 30cm Mercury Ion Engine was designed, fabricated and tested to determine compliance with electrical specifications. The power processor breadboard used the silicon controlled rectifier (SCR) series resonant inverter as the basic power stage to process all the power to an ion engine. The power processor includes a digital interface unit to process all input commands and internal telemetry signals so that operation is compatible with a central computer system. The breadboard was tested in a thermal vacuum environment. Integration tests were performed with the ion engine and demonstrate operational compatibility and reliable operation without any component failures. Electromagnetic interference data were also recorded on the design to provide information on the interaction with total spacecraft.

  3. Usability testing and requirements derivation for EMU-compatible electrical connectors

    NASA Technical Reports Server (NTRS)

    Reaux, Ray A.; Griffin, Thomas J.; Lewis, Ruthan

    1989-01-01

    On-orbit servicing of payloads is simplified when a spacecraft has been designed for serviceability. A key design criterion for a serviceable spaceraft is standardization of electrical connectors. This paper investigates the effects of extravehicular mobility unit (EMU) glove size, connector size, and connector type on usability of electrical connectors. An experiment was conducted exploring participants' ability to mate and demate connectors in an evacuated glovebox. Independent variables were two EMU glove-sizes, five connector size groups, and seven connector types. Significant differences in performance times and heart rate changes during mate and demate operations were found. Subjective assessments of connectors were collected from participants with a usability questionnaire. The data were used to derive design recommendations for a NASA-recommended EMU-compatible electrical connector.

  4. NASA Hydrogen Peroxide Propellant Hazards Technical Manual

    NASA Technical Reports Server (NTRS)

    Baker, David L.; Greene, Ben; Frazier, Wayne

    2005-01-01

    The Fire, Explosion, Compatibility and Safety Hazards of Hydrogen Peroxide NASA technical manual was developed at the NASA Johnson Space Center White Sands Test Facility. NASA Technical Memorandum TM-2004-213151 covers topics concerning high concentration hydrogen peroxide including fire and explosion hazards, material and fluid reactivity, materials selection information, personnel and environmental hazards, physical and chemical properties, analytical spectroscopy, specifications, analytical methods, and material compatibility data. A summary of hydrogen peroxide-related accidents, incidents, dose calls, mishaps and lessons learned is included. The manual draws from art extensive literature base and includes recent applicable regulatory compliance documentation. The manual may be obtained by United States government agencies from NASA Johnson Space Center and used as a reference source for hazards and safe handling of hydrogen peroxide.

  5. Magnesium fluoride as energy storage medium for spacecraft solar thermal power systems

    NASA Technical Reports Server (NTRS)

    Lurio, Charles A.

    1992-01-01

    MgF2 was investigated as a phase-change energy-storage material for LEO power systems using solar heat to run thermal cycles. It provides a high heat of fusion per unit mass at a high melting point (1536 K). Theoretical evaluation showed the basic chemical compatibility of liquid MgF2 with refractory metals at 1600 K, though transient high pressures of H2 can occur in a closed container due to reaction with residual moisture. The compatibility was tested in two refractory metal containers for over 2000 h. Some showed no deterioration, while there was evidence that the fluoride reacted with hafnium in others. Corollary tests showed that the MgF2 supercooled by 10-30 K and 50-90 K.

  6. Designing and Testing of Self-Cleaning Recirculating Zebrafish Tanks.

    PubMed

    Nema, Shubham; Bhargava, Yogesh

    2016-08-01

    Maintenance of large number of zebrafish in captive conditions is a daunting task. This can be eased by the use of recirculating racks with self-cleaning zebrafish tanks. Commercially available systems are costly, and compatibility of intercompany products has never been investigated. Although various cost-effective designs and methods of construction of custom-made recirculating zebrafish racks are available in literature, the design of self-cleaning zebrafish tanks is still not available. In this study, we report the design and method of construction of the self-cleaning unit, which can be fitted in any zebrafish tank. We validated the design by investigating sediment cleaning process in rectangular and cylindrical tank geometries using time lapse imaging. Our results suggest that for both tank geometries, the tanks fitted with self-cleaning unit provided superior sediment cleaning than the tanks fitted with overflow-drain unit. Although the self-cleaning unit could clean the sediment completely from both geometries over prolonged period, the cleaning of sediments was faster in the cylindrical tank than the rectangular tank. In conclusion, cost and efforts of zebrafish maintenance could be significantly reduced through the installation of our self-cleaning unit in any custom-made zebrafish tank.

  7. Combinatorial compatibility as habit-controlling factor in lysozyme crystallization I. Monomeric and tetrameric F faces derived graph-theoretically

    NASA Astrophysics Data System (ADS)

    Strom, C. S.; Bennema, P.

    1997-03-01

    A series of two articles discusses possible morphological evidence for oligomerization of growth units in the crystallization of tetragonal lysozyme, based on a rigorous graph-theoretic derivation of the F faces. In the first study (Part I), the growth layers are derived as valid networks satisfying the conditions of F slices in the context of the PBC theory using the graph-theoretic method implemented in program FFACE [C.S. Strom, Z. Krist. 172 (1985) 11]. The analysis is performed in monomeric and alternative tetrameric and octameric formulations of the unit cell, assuming tetramer formation according to the strongest bonds. F (flat) slices with thickness Rdhkl ( {1}/{2} < R ≤ 1 ) are predicted theoretically in the forms 1 1 0, 0 1 1, 1 1 1. The relevant energies are established in the broken bond model. The relation between possible oligomeric specifications of the unit cell and combinatorially feasible F slice compositions in these orientations is explored.

  8. Design study of wind turbines 50 kW to 3000 kW for electric utility applications. Volume 2: Analysis and design

    NASA Technical Reports Server (NTRS)

    1976-01-01

    All possible overall system configurations, operating modes, and subsystem concepts for a wind turbine configuration for cost effective generation of electrical power were evaluated for both technical feasibility and compatibility with utility networks, as well as for economic attractiveness. A design optimization computer code was developed to determine the cost sensitivity of the various design features, and thus establish the configuration and design conditions that would minimize the generated energy costs. The preliminary designs of both a 500 kW unit and a 1500 kW unit operating in a 12 mph and 18 mph median wind speed respectively, were developed. The various design features and components evaluated are described, and the rationale employed to select the final design configuration is given. All pertinent technical performance data and component cost data is included. The costs of all major subassemblies are estimated and the resultant energy costs for both the 500 kW and 1500 kW units are calculated.

  9. Orbiter CIU/IUS communications hardware evaluation

    NASA Technical Reports Server (NTRS)

    Huth, G. K.

    1979-01-01

    The DOD and NASA inertial upper stage communication system design, hardware specifications and interfaces were analyzed to determine their compatibility with the Orbiter payload communications equipment (Payload Interrogator, Payload Signal Processors, Communications Interface Unit, and the Orbiter operational communications equipment (the S-Band and Ku-band systems). Topics covered include (1) IUS/shuttle Orbiter communications interface definition; (2) Orbiter avionics equipment serving the IUS; (3) IUS communication equipment; (4) IUS/shuttle Orbiter RF links; (5) STDN/TDRS S-band related activities; and (6) communication interface unit/Orbiter interface issues. A test requirement plan overview is included.

  10. HAL/S-FC compiler system functional specification

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The functional requirements to be met by the HAL/S-FC compiler, and the hardware and software compatibilities between the compiler system and the environment in which it operates are defined. Associated runtime facilities and the interface with the Software Development Laboratory are specified. The construction of the HAL/S-FC system as functionally separate units and the interfaces between those units is described. An overview of the system's capabilities is presented and the hardware/operating system requirements are specified. The computer-dependent aspects of the HAL/S-FC are also specified. Compiler directives are included.

  11. [Deployment surgery from the viewpoint of the German Red Cross].

    PubMed

    Grabarek, V

    1997-01-01

    The German military coinages "deployment medicine" and "deployment surgery" are unusual within the Red Cross Germany (DRK). For its (surgical) deployments, the DRK complies exclusively with the principles of the International Red Cross and Red Crescent Movement. The mobile surgical unit of the DRK's rapid module system is an intentionally "low-tech" medical/surgical unit that also does without any dispensable medical conveniences. For its purposes and objectives it is optimally equipped, and enables the DRK to provide prompt and flexible regionally adjusted relief that is compatible with the Red Cross worldwide.

  12. Propulsion issues for advanced orbit transfer vehicles

    NASA Technical Reports Server (NTRS)

    Cooper, L. P.

    1984-01-01

    Studies of the United States Space Transportation System show that in the mid to late 1990s expanded capabilities for orbital transfer vehicles (OTV) will be needed to meet increased payload requirements for transporting materials and possibly men to geosynchronous orbit. Discussion and observations relative to the propulsion system issues of space basing, aeroassist compatibility, man ratability and enhanced payload delivery capability are presented. These issues will require resolution prior to the development of a propulsion system for the advanced OTV. The NASA program in support of advanced propulsion for an OTV is briefly described along with conceptual engine design characteristics.

  13. Beliefs about infant feeding in China and the United States: implications for breastfeeding promotion.

    PubMed

    Schulze, Pamela A; Zhao, Baomei; Young, Cathleen E

    2009-01-01

    This study investigates cultural differences in mothers' views regarding infant feeding and socialization. The majority of mothers reported breastfeeding as one of their methods of infant feeding, although more than half reported using both breast and bottle. Mothers in China expressed concerns that breastfeeding is not compatible with work outside of the home. American mothers were more likely to believe that breastfeeding is difficult to establish. "Happiness" was ranked the most important socialization goal by both groups. Public health initiatives must be culturally relevant and reflect an understanding of parenting values and beliefs.

  14. The ISPM unified radio and plasma wave experiment

    NASA Technical Reports Server (NTRS)

    Stone, R. G.; Caldwell, J.; Deconchy, Y.; Deschanciaux, C.; Ebbett, R.; Epstein, G.; Groetz, K.; Harvey, C. C.; Hoang, S.; Howard, R.

    1983-01-01

    Hardware for the International Solar Polar Mission (ISPM) Unified Radio and Plasma (URAP) wave experiment is presented. The URAP determines direction and polarization of distant radio sources for remote sensing of the heliosphere, and studies local wave phenomena which determine the transport coefficients of the ambient plasma. Electric and magnetic field antennas and preamplifiers; the electromagnetic compatibility plan and grounding; radio astronomy and plasma frequency receivers; a fast Fourier transformation data processing unit waveform analyzer; dc voltage measurements; a fast envelope sampler for the solar wind, and plasmas near Jupiter; a sounder; and a power converter are described.

  15. EVA - Don't Leave Earth Without It

    NASA Technical Reports Server (NTRS)

    Cupples, J. Scott; Smith, Stephen A.

    2011-01-01

    Modern manned space programs come in two categories: those that need Extravehicular Activity (EVA) and those that will need EVA. This paper discusses major milestones in the Shuttle Program where EVA was used to save payloads, enhance on-orbit capabilities, and build structures in order to ensure success of National Aeronautics and Space Administration (NASA) missions. In conjunction, the Extravehicular Mobility Unit s (EMU) design, and hence, its capabilities evolved as its mission evolved. It is the intent that lessons can be drawn from these case studies so that EVA compatibility is designed into future vehicles and payloads.

  16. Design, Planning and Management of the Hospital Custody Unit at Hospital Universitario Fundación Alcorcón.

    PubMed

    Fuente-Martín, C de la; Fuente Martín, B de la; Grifol-Clar, E

    2017-12-01

    The design and management of a Hospital Custody Unit at Hospital Universitario Fundación Alcorcón, to focus the aim of this study on specialized medical care for extra-penitentiary patients who have suffered from a disease. We are building a new space to facilitate their daily lives at hospital and we want to offer a double function to the patients that consists of a custody space and a health rehabilitation space. We carried out a scientific literature search on the international and national databases, about Hospital Custody Units or Restricted Access Units. The language of the reviews that we checked was English and Spanish. We wrote the Action Guide of the Hospital Custody Unit for the design, planning and management of the Hospital Custody Unit at Hospital Universitario Fundación Alcorcón. (We included complementary bibliographic material and the Quick Guide in the Unit). The Hospital Custody Unit will be compatible with medical activity, occupational safety and the custody of patients that are in prison. We thus require consensus with police departments about custody protocols along with assistance from the clinicians' teams at penitentiary centers and referral hospitals. Furthermore, it is important to step up special care for mental health and to promote telemedicine and new technologies to streamline medical care along with coordination with healthcare professionals.

  17. Statistical Analysis of Solar PV Power Frequency Spectrum for Optimal Employment of Building Loads

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olama, Mohammed M; Sharma, Isha; Kuruganti, Teja

    In this paper, a statistical analysis of the frequency spectrum of solar photovoltaic (PV) power output is conducted. This analysis quantifies the frequency content that can be used for purposes such as developing optimal employment of building loads and distributed energy resources. One year of solar PV power output data was collected and analyzed using one-second resolution to find ideal bounds and levels for the different frequency components. The annual, seasonal, and monthly statistics of the PV frequency content are computed and illustrated in boxplot format. To examine the compatibility of building loads for PV consumption, a spectral analysis ofmore » building loads such as Heating, Ventilation and Air-Conditioning (HVAC) units and water heaters was performed. This defined the bandwidth over which these devices can operate. Results show that nearly all of the PV output (about 98%) is contained within frequencies lower than 1 mHz (equivalent to ~15 min), which is compatible for consumption with local building loads such as HVAC units and water heaters. Medium frequencies in the range of ~15 min to ~1 min are likely to be suitable for consumption by fan equipment of variable air volume HVAC systems that have time constants in the range of few seconds to few minutes. This study indicates that most of the PV generation can be consumed by building loads with the help of proper control strategies, thereby reducing impact on the grid and the size of storage systems.« less

  18. The link between mental rotation ability and basic numerical representations

    PubMed Central

    Thompson, Jacqueline M.; Nuerk, Hans-Christoph; Moeller, Korbinian; Cohen Kadosh, Roi

    2013-01-01

    Mental rotation and number representation have both been studied widely, but although mental rotation has been linked to higher-level mathematical skills, to date it has not been shown whether mental rotation ability is linked to the most basic mental representation and processing of numbers. To investigate the possible connection between mental rotation abilities and numerical representation, 43 participants completed four tasks: 1) a standard pen-and-paper mental rotation task; 2) a multi-digit number magnitude comparison task assessing the compatibility effect, which indicates separate processing of decade and unit digits; 3) a number-line mapping task, which measures precision of number magnitude representation; and 4) a random number generation task, which yields measures both of executive control and of spatial number representations. Results show that mental rotation ability correlated significantly with both size of the compatibility effect and with number mapping accuracy, but not with any measures from the random number generation task. Together, these results suggest that higher mental rotation abilities are linked to more developed number representation, and also provide further evidence for the connection between spatial and numerical abilities. PMID:23933002

  19. High Frequency of Human Blood in Triatoma dimidiata Captured Inside Dwellings in a Rural Community in the Yucatan Peninsula, Mexico, but Low Antibody Seroprevalence and Electrocardiographic Findings Compatible with Chagas Disease in Humans

    PubMed Central

    Monteon, Victor; Alducin, César; Hernández, Jorge; Ramos-Ligonio, Angel; Lopez, Ruth

    2013-01-01

    We studied a small rural community of 411 inhabitants localized in the state of Campeche in the Yucatan Peninsula, Mexico. In 44 collected triatomines captured inside the houses, human feeding source was revealed in 23 of 44 (52%) samples, and chicken feeding source was revealed in 16 of 44 (36%) samples. In a set of 29 triatomines, mouse was the feeding source in 13 (44%) samples, and dog was the feeding source in 7 (24%) samples. Infection index with Trypanosoma cruzi in collected triatomines was 38%, and all parasites belonged to discrete type unit I. Inhabitants referred high contact with triatomine's bite in 60 of 128 (47%) samples, but seroprevalence was 2.3% (3/128). Evidence of electrocardiographic alteration compatible with Chagas disease was observed only in one asymptomatic seropositive subject. In conclusion, Triatoma dimidiata in this region are preferentially infected with T. cruzi I and feed on human beings with relative high frequency, but seroprevalence and Chagas disease in humans is relatively low. PMID:23296447

  20. Real-time endoscopic guidance using near-infrared fluorescent light for thoracic surgery

    NASA Astrophysics Data System (ADS)

    Venugopal, Vivek; Stockdale, Alan; Neacsu, Florin; Kettenring, Frank; Frangioni, John V.; Gangadharan, Sidharta P.; Gioux, Sylvain

    2013-03-01

    Lung cancer is the leading cause of cancer death in the United States, accounting for 28% of all cancer deaths. Standard of care for potentially curable lung cancer involves preoperative radiographic or invasive staging, followed by surgical resection. With recent adjuvant chemotherapy and radiation studies showing a survival advantage in nodepositive patients, it is crucial to accurately stage these patients surgically in order to identify those who may benefit. However, lymphadenectomy in lung cancer is currently performed without guidance, mainly due to the lack of tools permitting real-time, intraoperative identification of lymph nodes. In this study we report the design and validation of a novel, clinically compatible near-infrared (NIR) fluorescence thoracoscope for real-time intraoperative guidance during lymphadenectomy. A novel, NIR-compatible, clinical rigid endoscope has been designed and fabricated, and coupled to a custom source and a dual channel camera to provide simultaneous color and NIR fluorescence information to the surgeon. The device has been successfully used in conjunction with a safe, FDA-approved fluorescent tracer to detect and resect mediastinal lymph nodes during thoracic surgery on Yorkshire pigs. Taken together, this study lays the foundation for the clinical translation of endoscopic NIR fluorescence intraoperative guidance and has the potential to profoundly impact the management of lung cancer patients.

  1. Strategic Forum. Number 254, February 2010. U.S.-Mexico Homeland Defense: A Compatible Interface

    DTIC Science & Technology

    2010-02-01

    United States, and the creation of a Mexican P–47 Thunderbolt fighter squadron called the “ Aztec Eagles.” The 201st Mexican Fighter Squadron, Mexican... decline in trade started in 2001 and continued through 2003, with substantial recovery in 2005 and 2006. These trade fig- ures make clear that an

  2. Evaluating the compatibility of American and Mexican national forest inventory data

    Treesearch

    Todd A. Schroeder; Sean P. Healey; Gretchen G. Moisen

    2012-01-01

    The international border region between the United States and Mexico represents a point of discontinuity in forest policy, land use management and resource utilization practices. These differences along with physical barriers which separate the two countries can interact to alter the structure and functioning of forest vegetation. One valuable source of information for...

  3. Guayule (parthenium argentatum) pyrolysis biorefining: production of hydrocarbon compatible bio-oils from guayule bagasse via tail-gas reactive pyrolysis

    USDA-ARS?s Scientific Manuscript database

    Guayule (Parthenium argentatum) is a woody desert shrub grown in the southwestern United States as a source of natural rubber, organic resins, and high energy biofuel feedstock from crop residues. We used guayule bagasse, the residual biomass after latex extraction as feedstock in a pyrolysis proces...

  4. Forest statistics for Southwest-South Alabama counties - 1990

    Treesearch

    William H. McWilliams; Patrick E. Miller; John S. Vissage

    1990-01-01

    Tabulated results were derived from data obtained during a recent forest inventory of southeast Alabama (fig. 1). Core tables (1 to 25) are compatible among Forest Inventory and Analysis units in the Eastern U.S. Other tables (26 to 43) supplement the information contained in the core tables. Comparisons are made between results of the 1990 inventory and previous...

  5. Planning, Management and Evaluation. Advanced Institutional Development Program (AIDP) Two-year College Consortium, Vol. 1, No. 1.

    ERIC Educational Resources Information Center

    McManis, Gerald L.

    The purpose of this manual is to offer assistance to colleges and universities involved with, or interested in, improvement in their fundamental administrative process in a manner compatible with the Planning, Management and Evaluation System (PME) approach articulated by the United States Office of Education. Planning is defined as that…

  6. State Adoption of Incentives to Promote Evidence-Based Practices in Behavioral Health Systems.

    PubMed

    Stewart, Rebecca E; Marcus, Steven C; Hadley, Trevor R; Hepburn, Brian M; Mandell, David S

    2018-06-01

    Despite the critical role behavioral health care payers can play in creating an incentive to use evidence-based practices (EBPs), little research has examined which incentives are used in public mental health systems, the largest providers of mental health care in the United States. The authors surveyed state mental health directors from 44 states about whether they used any of seven strategies to increase the use of EBPs. Participants also ranked attributes of each incentive on the basis of key characteristics of diffusion of innovation theory (perceived advantage, simplicity, compatibility, observability, and gradually implementable) and perceived effectiveness. Almost three-quarters of state directors endorsed using at least one financial incentive; most paid for training and technical assistance. Few used other incentives. Strategies perceived as simple and compatible were more readily adopted. Enhanced rates and paying for better outcomes were perceived as the most effective but were the least deployed, suggesting that simplicity and organizational compatibility may be the most decisive factors when choosing incentives. Payers are not using the incentives they perceive as most effective, and they are mostly using only one strategy for reasons of simplicity and compatibility. Future work should focus on barriers to measurement that likely hinder the adoption and implementation of paying for better outcomes and enhanced reimbursement rates, with the ultimate goal of measuring the effectiveness of incentives on EBP implementation efforts.

  7. Multi-imager compatible actuation principles in surgical robotics.

    PubMed

    Stoianovici, D

    2005-01-01

    Today's most successful surgical robots are perhaps surgeon-driven systems, such as the daVinci (Intuitive Surgical Inc., USA, www.intuitivesurgical.com). These have already enabled surgery that was unattainable with classic instrumentation; however, at their present level of development, they have limited utility. The drawback of these systems is that they are independent self-contained units, and as such, they do not directly take advantage of patient data. The potential of these new surgical tools lies much further ahead. Integration with medical imaging and information are needed for these devices to achieve their true potential. Surgical robots and especially their subclass of image-guided systems require special design, construction and control compared to industrial types, due to the special requirements of the medical and imaging environments. Imager compatibility raises significant engineering challenges for the development of robotic manipulators with respect to imager access, safety, ergonomics, and above all the non-interference with the functionality of the imager. These apply to all known medical imaging types, but are especially challenging for achieving compatibility with the class of MRI systems. Even though a large majority of robotic components may be redesigned to be constructed of MRI compatible materials, for other components such as the motors used in actuation, prescribing MRI compatible materials alone is not sufficient. The electromagnetic motors most commonly used in robotic actuation, for example, are incompatible by principle. As such, alternate actuation principles using "intervention friendly" energy should be adopted and/or devised for these special surgical and radiological interventions. This paper defines the new concept of Multi-Imager Compatibility of surgical manipulators and describes its requirements. Subsequently, the paper gives several recommendations and proposes new actuation principles for this concept. Several implementations have been constructed and tested, and the results are presented here. This is the first paper addressing these issues. Copyright 2005 Robotic Publications Ltd.

  8. Evaluating arguments during instigations of defence motivation and accuracy motivation.

    PubMed

    Liu, Cheng-Hong

    2017-05-01

    When people evaluate the strength of an argument, their motivations are likely to influence the evaluation. However, few studies have specifically investigated the influences of motivational factors on argument evaluation. This study examined the effects of defence and accuracy motivations on argument evaluation. According to the compatibility between the advocated positions of arguments and participants' prior beliefs and the objective strength of arguments, participants evaluated four types of arguments: compatible-strong, compatible-weak, incompatible-strong, and incompatible-weak arguments. Experiment 1 revealed that participants possessing a high defence motivation rated compatible-weak arguments as stronger and incompatible-strong ones as weaker than participants possessing a low defence motivation. However, the strength ratings between the high and low defence groups regarding both compatible-strong and incompatible-weak arguments were similar. Experiment 2 revealed that when participants possessed a high accuracy motivation, they rated compatible-weak arguments as weaker and incompatible-strong ones as stronger than when they possessed a low accuracy motivation. However, participants' ratings on both compatible-strong and incompatible-weak arguments were similar when comparing high and low accuracy conditions. The results suggest that defence and accuracy motivations are two major motives influencing argument evaluation. However, they primarily influence the evaluation results for compatible-weak and incompatible-strong arguments, but not for compatible-strong and incompatible-weak arguments. © 2016 The British Psychological Society.

  9. Operability of Space Station Freedom's meteoroid/debris protection system

    NASA Technical Reports Server (NTRS)

    Kahl, Maggie S.; Stokes, Jack W.

    1992-01-01

    The design of Space Station Freedom's external structure must not only protect the spacecraft from the hazardous environment, but also must be compatible with the extra vehicular activity system for assembly and maintenance. The external procedures for module support are utility connections, external orbital replaceable unit changeout, and maintenance of the meteoroid/debris shields and multilayer insulation. All of these interfaces require proper man-machine engineering to be compatible with the extra vehicular activity and manipulator systems. This paper discusses design solutions, including those provided for human interface, to the Space Station Freedom meteoroid/debris protection system. The system advantages and current access capabilities are illustrated through analysis of its configuration over the Space Station Freedom resource nodes and common modules, with emphasis on the cylindrical sections and endcones.

  10. Magnesium fluoride as energy storage medium for spacecraft solar thermal power systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lurio, C.A.

    1992-10-01

    MgF2 was investigated as a phase-change energy-storage material for LEO power systems using solar heat to run thermal cycles. It provides a high heat of fusion per unit mass at a high melting point (1536 K). Theoretical evaluation showed the basic chemical compatibility of liquid MgF2 with refractory metals at 1600 K, though transient high pressures of H2 can occur in a closed container due to reaction with residual moisture. The compatibility was tested in two refractory metal containers for over 2000 h. Some showed no deterioration, while there was evidence that the fluoride reacted with hafnium in others. Corollarymore » tests showed that the MgF2 supercooled by 10-30 K and 50-90 K. 24 refs.« less

  11. Analysis of the Spanish CCR5-∆32 inventory of cord blood units: lower cell counts in homozygous donors.

    PubMed

    Enrich, Emma; Vidal, Francisco; Sánchez-Gordo, Francisco; Gómez-Zumaquero, Juan M; Balas, Antonio; Rudilla, Francesc; Barea, Luisa; Castro, Ana; Larrea, Luis; Perez-Vaquero, Miguel A; Prat, Isidro; Querol, Sergio; Garrido, Gregorio; Matesanz, Rafael; Carreras, Enric; Duarte, Rafael F

    2018-02-06

    The possibility to use CCR5-∆32 umbilical cord blood to cure HIV infection in patients in need of a hematopoietic transplant has been suggested. The less stringent HLA compatibility needed in this type of transplant facilitates the search of a suitable donor having the CCR5-∆32 mutation. To achieve an inventory of CCR5-∆32 cord blood units, the 20,236 best cell quality units of the Spanish Registry were genotyped. Furthermore, their CD34 + and total nucleated cells counts, blood type, gender, HLA and donor's geographical and ancestral origin were analyzed. The results showed 130 (0.64%) units homozygous for the deletion, 2,646 (13.08%) heterozygous and 17,460 (86.28%) did not present the mutation. Interestingly, a significant lower amount of CD34 + cells was found in the CCR5-∆32 homozygous units. In addition, a significant association was found among donor's ancestral origin and the mutation, with a higher percentage of CCR5-∆32 units with a European ancestry. In summary, identification of a relatively high number of CCR5-∆32 units is feasible and will facilitate the development of clinical trials for HIV cure in patients requiring hematopoietic transplantation. Further studies are required to understand the significance of lower cell counts within the CCR5-∆32 homozygous group and its clinical impact.

  12. Clinical Observation of Factors in the Efficacy of Blood Component Transfusion in Patients following Hematopoietic Stem Cell Transplantation

    PubMed Central

    Zhang, Xi; Xiao, Yanni; Ran, Qian; Liu, Yao; Duan, Qianbi; Duan, Huiling; Ye, Xingde; Li, Zhongjun

    2012-01-01

    Background Factors affecting the efficacy of platelet and red blood cell (RBC) transfusion in patients undergoing hematopoietic stem cell transplantation (HSCT) have not been studied extensively. We aimed to evaluate platelet and RBC transfusion efficacy by measuring the platelet corrected count increment and the hemoglobin increment, respectively, 24 h after transfusion in 105 patients who received HSCT. Methodology/Principal Findings Using retrospective analysis, we studied whether factors, including gender, time of transplantation, the compatibility of ABO group between HSC donors and recipients, and autologous or allogenic transplantation, influence the efficacy of blood component transfusion. We found that the infection rate of HSCT patients positively correlated with the transfusion amount, and the length of stay in the laminar flow room was associated with transfusion. We found that platelet transfusion performed during HSCT showed significantly better efficacy than that performed before HSCT. The effect of platelet transfusion in auto-transplantation was significantly better than that in allo-transplantation. The efficacy of RBC transfusion during HSCT was significantly lower than that performed before HSCT. The efficacy of RBC transfusion in auto-transplantation was significantly higher than that in allo-transplantation. Allo-transplantation patients who received HSCs from compatible ABO groups showed significantly higher efficacy during both platelet and RBC transfusion. Conclusions We conclude that the efficacy of platelet and RBC transfusions does not correlate with the gender of patients, while it significantly correlates with the time of transplantation, type of transplantation, and ABO compatibility between HSC donors and recipients. During HSCT, the infection rate of patients positively correlates with the transfusion amount of RBCs and platelets. The total volume of RBC units transfused positively correlates with the length of the patients’ stay in the laminar flow room. PMID:22701516

  13. HLA AND CROSS·REACTIVE ANTIGEN GROUP MATCHING FOR CADAVER KIDNEY ALLOCATION1

    PubMed Central

    Starzl, Thomas E.; Eliasziw, Michael; Gjertson, David; Terasaki, Paul I.; Fung, John J.; Trucco, Massimo; Martell, Joan; McMichael, John; Scantlebury, Velma; Shapiro, Ron; Donner, Allan

    2010-01-01

    Background Allocation of cadaver kidneys by graded human leukocyte antigen (HLA) compatibility scoring arguably has had little effect on overall survival while prejudicing the transplant candidacy of African-American and other hard to match populations. Consequently, matching has been proposed of deduced amino acid residues of the individual HLA molecules shared by cross-reactive antigen groups (CREGs). We have examined the circumstances under which compatibility with either method impacted graft survival. Methods Using Cox proportional hazards regression modeling, we studied the relationship between levels of conventional HLA mismatch and other donor and recipient factors on primary cadaver kidney survival between 1981 and 1995 at the University of Pittsburgh (n=1,780) and in the United Network for Organ Sharing (UNOS) Scientific Registry during 1991–1995 (n=31,291). The results were compared with those obtained by the matching of amino acid residues that identified CREG-compatible cases with as many as four (but not five and six) HLA mismatches. Results With more than one HLA mismatch (>85% of patients in both series), most of the survival advantage of a zero mismatch was lost. None of the HLA loci were “weak.” In the UNOS (but not Pittsburgh) category of one-HLA mismatch (n=1334), a subgroup of CREG-matched recipients (35.3%) had better graft survival than the remaining 64.7%, who were CREG-mismatched. There was no advantage of a CREG match in the two- to four-HLA incompatibility tiers. Better graft survival with tacrolimus was observed in both the Pittsburgh and UNOS series. Conclusions Obligatory national sharing of cadaver kidneys is justifiable only for zero-HLA-mismatched kidneys. The potential value of CREG matching observed in the one-HLA-mismatched recipients of the UNOS (but not the Pittsburgh) experience deserves further study. PMID:9381546

  14. The perceived compatibility of safety and production expectations in hazardous occupations.

    PubMed

    McLain, David L; Jarrell, Kimberly A

    2007-01-01

    Safety hazards are unavoidable in many work environments. Employees must be both productive and safe, however, conflicting safety and production demands can negatively affect safety, production, or both. The employee's perception of the compatibility of management's safety and production expectations is a possible predictor of such consequences. This paper defines "safety-production compatibility" and describes how measures of safety-production compatibility, as well as safety pressure and production pressure, were developed. We used LISREL structural equation modeling to test the influences of safety-production compatibility, safety pressure, and production pressure on safe work behavior and interference with performing other work tasks. The 239 study participants were workers employed in diverse but hazardous occupations. Pressure to work safely was positively associated with safe work behavior. The perceived compatibility of safety and production demands positively influenced safe work behavior and reduced the interference of safety hazards performing other tasks. Safety-production compatibility was also found to mediate the relationship between trust in management and safe work behavior. The results of this field study suggest increased compatibility, and thus less conflict, between safety and production demands influences safe work behavior and the interference of safety hazards with performing other work tasks. More broadly, the worker's reaction to multiple work demands is a safety and performance influence. Safety management efforts that focus only on the hazards fail to eliminate many accidents because accidents arise from many factors including technology, safety climate, social influences, production, and safety demands. This study suggests that workers differ in their perception of the compatibility of safety and production demands. These differences will show up in safe work behavior, influencing the effectiveness of safety management efforts and the trust workers have in management's concern for safety.

  15. Design, development, and field demonstration of a remotely deployable water quality monitoring system

    NASA Technical Reports Server (NTRS)

    Wallace, J. W.; Lovelady, R. W.; Ferguson, R. L.

    1981-01-01

    A prototype water quality monitoring system is described which offers almost continuous in situ monitoring. The two-man portable system features: (1) a microprocessor controlled central processing unit which allows preprogrammed sampling schedules and reprogramming in situ; (2) a subsurface unit for multiple depth capability and security from vandalism; (3) an acoustic data link for communications between the subsurface unit and the surface control unit; (4) eight water quality parameter sensors; (5) a nonvolatile magnetic bubble memory which prevents data loss in the event of power interruption; (6) a rechargeable power supply sufficient for 2 weeks of unattended operation; (7) a water sampler which can collect samples for laboratory analysis; (8) data output in direct engineering units on printed tape or through a computer compatible link; (9) internal electronic calibration eliminating external sensor adjustment; and (10) acoustic location and recovery systems. Data obtained in Saginaw Bay, Lake Huron are tabulated.

  16. The Plasma-Lyte 148 v Saline (PLUS) study protocol: a multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality.

    PubMed

    Hammond, Naomi E; Bellomo, Rinaldo; Gallagher, Martin; Gattas, David; Glass, Parisa; Mackle, Diane; Micallef, Sharon; Myburgh, John; Saxena, Manoj; Taylor, Colman; Young, Paul; Finfer, Simon

    2017-09-01

    0.9% sodium chloride (saline) is the most commonly administered resuscitation fluid on a global basis but emerging evidence suggests that its high chloride content may have important adverse effects. To describe the study protocol for the Plasma- Lyte 148 v Saline study, which will test the hypothesis that in critically ill adult patients the use of Plasma-Lyte 148 (a buffered crystalloid solution) for fluid therapy results in different 90-day all-cause mortality when compared with saline. We will conduct this multicentre, blinded, randomised controlled trial in approximately 50 intensive care units in Australia and New Zealand. We will randomly assign 8800 patients to either Plasma-Lyte 148 or saline for all resuscitation fluid, maintenance fluid and compatible drug dilution therapy while in the ICU for up to 90 days after randomisation. The primary outcome is 90-day all-cause mortality; secondary outcomes include mean and peak creatinine concentration, incidence of renal replacement therapy, incidence and duration of vasoactive drug treatment, duration of mechanical ventilation, ICU and hospital length of stay, and quality of life and health services use at 6 months. The PLUS study will provide high-quality data on the comparative safety and efficacy of Plasma-Lyte 148 compared with saline for resuscitation and compatible crystalloid fluid therapy in critically ill adult patients.

  17. Aluminum recycling in the United States in 2000

    USGS Publications Warehouse

    Plunkert, Patricia A.

    2006-01-01

    As one of a series of reports on metals recycling, this report discusses the flow of aluminum from production through its uses with particular emphasis on the recycling of industrial scrap (new scrap) and used products (old scrap) in 2000. This materials flow study includes a description of aluminum supply and demand factors for the United States to illustrate the extent of aluminum recycling and to identify recycling trends. Understanding the system of materials flow from source to ultimate disposition can assist in improving the management of natural resources in a manner that is compatible with sound environmental practices. In 2000, the old scrap recycling efficiency for aluminum was estimated to be 42 percent. Almost 60 percent of the aluminum that was recycled in 2000 came from new scrap, and the recycling rate was estimated to be 36 percent. The principal source of old scrap was recycled aluminum beverage cans.

  18. Corrective lens use and refractive error among United States Air Force aircrew.

    PubMed

    Wright, Steve T; Ivan, Douglas J; Clark, Patrick J; Gooch, John M; Thompson, William

    2010-03-01

    Corrective lens use by military aviators is an important consideration in the design of head-mounted equipment. The United States Air Force (USAF) has periodically monitored lens use by aviators; however, it has been over a decade since the last study. We provide an update on the prevalence of corrective lenses and refractive error among USAF aircrew based on eyeglass orders processed through the Spectacle Request Transmission System (SRTS). Currently, 41% of active duty USAF pilots and 54% of other aircrew require corrective lenses to perform flight duties. Refractive errors are characterized by low to moderate levels of myopia with a mean spherical equivalent power of -1.01 diopters (D) for pilots and -1.68 D for others. Contact lenses, and more recently refractive surgery, reduce the number of aircrew that must rely on spectacles when flying; however, spectacle compatibility remains an important consideration in the cockpit.

  19. Treatment barriers identified by substance abusers assessed at a centralized intake unit.

    PubMed

    Rapp, Richard C; Xu, Jiangmin; Carr, Carey A; Lane, D Tim; Wang, Jichuan; Carlson, Robert

    2006-04-01

    The 59-item Barriers to Treatment Inventory (BTI) was administered to 312 substance abusers at a centralized intake unit following assessment but before treatment entry to assess their views on barriers to treatment. Factor analysis identified 25 items in 7 well-defined latent constructs: Absence of Problem, Negative Social Support, Fear of Treatment, Privacy Concerns, Time Conflict, Poor Treatment Availability, and Admission Difficulty. The factorial structure of the barriers is consistent with the findings of other studies that asked substance abusers about barriers to treatment and is conceptually compatible with Andersen's model of health care utilization. Factors were moderately to highly correlated, suggesting that they interact with one another. Selected characteristics were generally not predictive of barrier factors. Overall, results indicate that the BTI has good content validity and is a reliable instrument for assessing barriers to drug treatment. The potential utility of the BTI in assessment settings is discussed.

  20. Informing rangeland stewardship with research: lessons learned from Yolo County, California

    Treesearch

    Vance Russell; Chris Rose; Miles DaPrato

    2008-01-01

    Approximately 70 percent of the contiguous United States is in private lands with half of this total in row crop or rangelands. Audubon California’s Landowner Stewardship Program engages with farmers and ranchers on conservation and restoration projects in a manner compatible with existing agricultural operations. To assess the success of these efforts, Audubon,...

  1. Working to make the Clean Air Act and prescribed burning compatible

    Treesearch

    Trent Procter

    1995-01-01

    The Federal Clean Air Act of 1963 offers a challenge to the future of prescribed and natural fire programs in the United States. One aspect of maintaining healthy ecosystems for humans and natural resources is clean air. In addition, prescribed and natural fire programs are an important tool in maintaining healthy ecosystems, as well as satisfying the requirements of...

  2. Forest statistics for Southwest-North Alabama counties - 1990

    Treesearch

    William H. McWilliams; Patrick E. Miller; John S. Vissage

    1990-01-01

    Tabulated results were derived from data obtained during a recent forest inventory of southwest-North Alabama (fig. I). Core tables (1 to 25) are compatible among Forest Inventory and Analysis units in the Eastern U.S. Other tables (26 to 43) supplement the information contained in the core tables. Comparisons are made between results of the 1990 inventory and previous...

  3. Alternative timing of carbaryl treatments for protecting lodgepole pine from mortality attributed to mountain pine beetle

    Treesearch

    Christopher J. Fettig; A.Steve Munson; Kenneth E. Gibson

    2015-01-01

    Carbaryl is regarded among the most effective, economically viable, and ecologically-compatible insecticides available for protecting conifers from bark beetle attack in the western United States. Treatments are typically applied in spring prior to initiation of bark beetle flight for that year. We evaluated the efficacy of spring and fall applications for protecting...

  4. 67 FR 24495 - United States v. Microsoft Corporation; Public Comments; Notice (MTC-00003461 - MTC-00007629)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2002-05-03

    ... (web-serving software), Linux, Perl, and those who are building a compatible & free version of MS`s..., Argument from Design Argument from Design-Web & Multimedia [email protected] http://www.ardes.com MTC-00003464... organization could be a good target for this effort. Their web address is http:// www.gnu.org/. This effort...

  5. Multiprocessor sparse L/U decomposition with controlled fill-in

    NASA Technical Reports Server (NTRS)

    Alaghband, G.; Jordan, H. F.

    1985-01-01

    Generation of the maximal compatibles of pivot elements for a class of small sparse matrices is studied. The algorithm involves a binary tree search and has a complexity exponential in the order of the matrix. Different strategies for selection of a set of compatible pivots based on the Markowitz criterion are investigated. The competing issues of parallelism and fill-in generation are studied and results are provided. A technque for obtaining an ordered compatible set directly from the ordered incompatible table is given. This technique generates a set of compatible pivots with the property of generating few fills. A new hueristic algorithm is then proposed that combines the idea of an ordered compatible set with a limited binary tree search to generate several sets of compatible pivots in linear time. Finally, an elimination set to reduce the matrix is selected. Parameters are suggested to obtain a balance between parallelism and fill-ins. Results of applying the proposed algorithms on several large application matrices are presented and analyzed.

  6. Development and fabrication of heat-sterilizable inhalation therapy equipment

    NASA Technical Reports Server (NTRS)

    Irons, A. S.

    1974-01-01

    The development of a completely heat sterilizable intermittent positive pressure breathing (IPPB) ventilator in an effort to reduce the number of hospital acquired infections is reported. After appropriate changes in materials and design were made, six prototype units were fabricated and were successfully field tested in local hospitals. Most components of the modified ventilators are compatible with existing machines. In all but a few instances, such as installation of bacteria-retentive filters and a modified venturi, the change over from non-heat-sterilizable to sterilizable units was accomplished by replacement of heat labile materials with heat stable materials.

  7. Maintaining health sector collaborations between United States non-governmental organizations and North Korea through innovation and planning.

    PubMed

    Yim, Eugene S; Choi, Ricky Y; VanRooyen, Michael

    2009-01-01

    Humanitarian agencies in North Korea operate within a complex sociopolitical environment historically characterized by a baseline of mistrust. As a result of operating within such a heated environment, health sector collaborations between such agencies and the North Korean government have followed unpredictable courses. The factors that have contributed to successful programmatic collaborations, as perceived by United States non-governmental organizations (NGOs) and North Korean officials were investigated. A qualitative, multi-case, comparative, research design using semistructured interviews was used. Expert North Korean informants were interviewed to generate a list of factors contributing to programmatic success, defined as fulfilling mutually established objectives through collaboration. The North Korean informants were asked to identify US NGOs that fulfill these criteria ("mission-compatible NGOs"). Representatives from all of the mission compatible NGOs were interviewed. All informants provided their perspectives on the factors that contributed to successful programmatic collaborations. The interviews were recorded, transcribed, and analyzed for thematic content. North Korean informants identified six mission-compatible US NGOs. The North Korean and US NGO informants provided a number of factors that contributed to successful programs. These factors were grouped into the following themes: (1) responsiveness to North Korean requests; (2) resident status; (3) program monitoring; (4) sincerity (apolitical objectives); (5) information gathering; and (6) interagency collaboration. Some US NGOs have devised innovative measures to work within a unique set of parameters in North Korea. Both US NGOs and North Korean authorities have made significant concessions to maintain their programmatic partnerships. In this manner, seasoned collaborators have employed creative strategies and a form of health diplomacy to facilitate programmatic success in North Korea by building trust within a complex sociopolitical space.

  8. ITER Disruption Mitigation System Design

    NASA Astrophysics Data System (ADS)

    Rasmussen, David; Lyttle, M. S.; Baylor, L. R.; Carmichael, J. R.; Caughman, J. B. O.; Combs, S. K.; Ericson, N. M.; Bull-Ezell, N. D.; Fehling, D. T.; Fisher, P. W.; Foust, C. R.; Ha, T.; Meitner, S. J.; Nycz, A.; Shoulders, J. M.; Smith, S. F.; Warmack, R. J.; Coburn, J. D.; Gebhart, T. E.; Fisher, J. T.; Reed, J. R.; Younkin, T. R.

    2015-11-01

    The disruption mitigation system for ITER is under design and will require injection of up to 10 kPa-m3 of deuterium, helium, neon, or argon material for thermal mitigation and up to 100 kPa-m3 of material for suppression of runaway electrons. A hybrid unit compatible with the ITER nuclear, thermal and magnetic field environment is being developed. The unit incorporates a fast gas valve for massive gas injection (MGI) and a shattered pellet injector (SPI) to inject a massive spray of small particles, and can be operated as an SPI with a frozen pellet or an MGI without a pellet. Three ITER upper port locations will have three SPI/MGI units with a common delivery tube. One equatorial port location has space for sixteen similar SPI/MGI units. Supported by US DOE under DE-AC05-00OR22725.

  9. Magnetic resonance imaging compatible remote catheter navigation system with 3 degrees of freedom.

    PubMed

    Tavallaei, M A; Lavdas, M K; Gelman, D; Drangova, M

    2016-08-01

    To facilitate MRI-guided catheterization procedures, we present an MRI-compatible remote catheter navigation system that allows remote navigation of steerable catheters with 3 degrees of freedom. The system consists of a user interface (master), a robot (slave), and an ultrasonic motor control servomechanism. The interventionalist applies conventional motions (axial, radial and plunger manipulations) on an input catheter in the master unit; this user input is measured and used by the servomechanism to control a compact catheter manipulating robot, such that it replicates the interventionalist's input motion on the patient catheter. The performance of the system was evaluated in terms of MRI compatibility (SNR and artifact), feasibility of remote navigation under real-time MRI guidance, and motion replication accuracy. Real-time MRI experiments demonstrated that catheter was successfully navigated remotely to desired target references in all 3 degrees of freedom. The system had an absolute value error of [Formula: see text]1 mm in axial catheter motion replication over 30 mm of travel and [Formula: see text] for radial catheter motion replication over [Formula: see text]. The worst case SNR drop was observed to be [Formula: see text]3 %; the robot did not introduce any artifacts in the MR images. An MRI-compatible compact remote catheter navigation system has been developed that allows remote navigation of steerable catheters with 3 degrees of freedom. The proposed system allows for safe and accurate remote catheter navigation, within conventional closed-bore scanners, without degrading MR image quality.

  10. MIPs in Aqueous Environments.

    PubMed

    Wan, Ying-chun; Ma, Hui-ting; Lu, Bin

    2015-01-01

    When organic solvent-compatible molecularly imprinted polymers (MIPs) are used in aqueous environment, how to reduce nonspecific binding is a major challenge. By modifying the binding solvents and introducing appropriate washing and elution steps, even relatively hydrophobic MIPs can gain optimal rebinding selectivity in aqueous conditions. Furthermore, water-compatible MIPs that can be used to treat aqueous samples directly have been prepared. The use of hydrophilic co-monomers, the controlled surface modification through controlled radical polymerization, and the new interfacial molecular imprinting methods are different strategies to prepare water-compatible MIPs. By combining MIPs with other techniques, both organic solvent-compatible and water-compatible MIPs can display better functional performances in aqueous conditions. Intensive studies on MIPs in aqueous conditions can provide new MIPs with much-improved compatibilities that will lead to more interesting applications in biomedicine and biotechnology.

  11. Antibody screening in multitransfused patients: a prerequisite before each transfusion.

    PubMed

    Lamba, Divjot S; Mittal, Kshitija; Sood, Tanvi; Bedi, Ravneet Kaur; Kaur, Paramjit; Kaur, Gagandeep

    2014-10-01

    Life-long red blood cell (RBC) transfusions remain the main treatment for severe thalassemia. We hereby report a case of anti S and anti Lu(a) in a β-thalassemia major patient detected incidentally on antibody screening. The patient was a known case of β-thalassemia major and was on regular blood transfusion every 3 weeks from the institute from the age of 6 months. Subsequently, on one occasion, patient's crossmatch was compatible despite positive antibody screen using microcolumn gel technique. Autocontrol and direct antiglobulin test were negative on microcolumn gel. Anti S and anti Lu(a) antibodies were identified. Blood unit found compatible was negative for S and Lu(a) antigens. Antibody titers were 1:1 for both anti S and anti Lu(a) in AHG phase using tube technique and antibodies were of IgG type. Blood unit was transfused uneventfully to the patient. Donors were traced back (last three donations) and called for repeat blood sample testing for S and Lu(a) antigen. Two out of three donors were found to be S antigen positive and one out of these two was Lu(a) antigen positive. Anti S and anti Lu(a) antibodies were again identified on patient's subsequent visit for transfusion. The present case re-emphasize the importance of antibody screening at each visit in earlier detection of antibodies in multi transfused patients. Encouraging patients to receive transfusion from one center and dedicating donors could reduce alloimmunization rate but larger studies are required. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. The Risk of Transplant Failure With HLA Mismatch in First Adult Kidney Allografts 2: Living Donors, Summary, Guide

    PubMed Central

    Williams, Robert C.; Opelz, Gerhard; Weil, E. Jennifer; McGarvey, Chelsea J.; Chakkera, Harini A.

    2017-01-01

    Background Allografts from living donors survive longer than those from deceased donors but the role of HLA mismatching in living kidney donation is still in question. We examined the effect of HLA compatibility on kidney allograft survival from living donors by studying all first adult kidney transplants performed in the United States over 25 years. Methods Using the United Network for Organ Sharing data, we identified first kidney transplants between October 1, 1987, and December 31, 2013. Recipients were classified by their number of HLA mismatches and stratified by donor origin. Cox multivariate regression analyses adjusting for recipient and donor transplant characteristics were performed to determine impact of HLA compatibility on kidney allograft survival for all living donors and for living related and living unrelated subsets. Results There were 66 596 first adult transplants from living donors with 348 960 years of follow-up. We found a linear relationship between HLA mismatch and allograft survival. In adjusted analyses, among all living donors, 1 mismatch conferred a 44% higher risk, whereas 6 mismatches conferred a twofold higher risk of allograft failure. When using 0-mismatched full siblings as a reference, living-donor kidneys reduce the hazard of failure by approximately 34% when compared with deceased donors. Twenty-five years of transplant experience, stratified by donor source, was summarized and presented as a guide for allocation. Conclusions These data reinforce the importance of optimizing HLA matching to further improve survival in first adult kidney allografts in the future, especially in living unrelated donations, when possible. PMID:28573187

  13. The Risk of Transplant Failure With HLA Mismatch in First Adult Kidney Allografts 2: Living Donors, Summary, Guide.

    PubMed

    Williams, Robert C; Opelz, Gerhard; Weil, E Jennifer; McGarvey, Chelsea J; Chakkera, Harini A

    2017-05-01

    Allografts from living donors survive longer than those from deceased donors but the role of HLA mismatching in living kidney donation is still in question. We examined the effect of HLA compatibility on kidney allograft survival from living donors by studying all first adult kidney transplants performed in the United States over 25 years. Using the United Network for Organ Sharing data, we identified first kidney transplants between October 1, 1987, and December 31, 2013. Recipients were classified by their number of HLA mismatches and stratified by donor origin. Cox multivariate regression analyses adjusting for recipient and donor transplant characteristics were performed to determine impact of HLA compatibility on kidney allograft survival for all living donors and for living related and living unrelated subsets. There were 66 596 first adult transplants from living donors with 348 960 years of follow-up. We found a linear relationship between HLA mismatch and allograft survival. In adjusted analyses, among all living donors, 1 mismatch conferred a 44% higher risk, whereas 6 mismatches conferred a twofold higher risk of allograft failure. When using 0-mismatched full siblings as a reference, living-donor kidneys reduce the hazard of failure by approximately 34% when compared with deceased donors. Twenty-five years of transplant experience, stratified by donor source, was summarized and presented as a guide for allocation. These data reinforce the importance of optimizing HLA matching to further improve survival in first adult kidney allografts in the future, especially in living unrelated donations, when possible.

  14. Compatibility of household budget and individual nutrition surveys: results of the preliminary analysis.

    PubMed

    Naska, A; Trichopoulou, A

    2001-08-01

    The EU-supported project entitled: "Compatibility of household budget and individual nutrition surveys and disparities in food habits" aimed at comparing individualised household budget survey (HBS) data with food consumption values derived from individual nutrition surveys (INS). The present paper provides a brief description of the methodology applied for rendering the datasets at a comparable level. Results of the preliminary evaluation of their compatibility are also presented. A non parametric modelling approach was used for the individualisation (age and gender-specific) of the food data collected at household level, in the context of the national HBSs and the bootstrap technique was used for the derivation of 95% confidence intervals. For each food group, INS and HBS-derived mean values were calculated for twenty-four research units, jointly defined by country (four countries involved), gender (male, female) and age (younger, middle-aged and older). Pearson correlation coefficients were calculated. The results of this preliminary analysis show that there is considerable scope in the nutritional information derived from HBSs. Additional and more sophisticated work is however required, putting particular emphasis on addressing limitations present in both surveys and on deriving reliable individual consumption point and interval estimates, on the basis of HBS data.

  15. A neural circuit transforming temporal periodicity information into a rate-based representation in the mammalian auditory system.

    PubMed

    Dicke, Ulrike; Ewert, Stephan D; Dau, Torsten; Kollmeier, Birger

    2007-01-01

    Periodic amplitude modulations (AMs) of an acoustic stimulus are presumed to be encoded in temporal activity patterns of neurons in the cochlear nucleus. Physiological recordings indicate that this temporal AM code is transformed into a rate-based periodicity code along the ascending auditory pathway. The present study suggests a neural circuit for the transformation from the temporal to the rate-based code. Due to the neural connectivity of the circuit, bandpass shaped rate modulation transfer functions are obtained that correspond to recorded functions of inferior colliculus (IC) neurons. In contrast to previous modeling studies, the present circuit does not employ a continuously changing temporal parameter to obtain different best modulation frequencies (BMFs) of the IC bandpass units. Instead, different BMFs are yielded from varying the number of input units projecting onto different bandpass units. In order to investigate the compatibility of the neural circuit with a linear modulation filterbank analysis as proposed in psychophysical studies, complex stimuli such as tones modulated by the sum of two sinusoids, narrowband noise, and iterated rippled noise were processed by the model. The model accounts for the encoding of AM depth over a large dynamic range and for modulation frequency selective processing of complex sounds.

  16. Science, religion, and society: the problem of evolution in America.

    PubMed

    Coyne, Jerry A

    2012-08-01

    American resistance to accepting evolution is uniquely high among First World countries. This is due largely to the extreme religiosity of the United States, which is much higher than that of comparably advanced nations, and to the resistance of many religious people to the facts and supposed implications of evolution. The prevalence of religious belief in the United States suggests that outreach by scientists alone will not have a huge effect in increasing the acceptance of evolution, nor will the strategy of trying to convince the faithful that evolution is compatible with their religion. Because creationism is a symptom of religion, another strategy to promote evolution involves loosening the grip of faith on America. This is easier said than done, for recent sociological surveys show that religion is highly correlated with the dysfunctionality of a society, and various measures of societal health show that the United States is one of the most socially dysfunctional First World countries. Widespread acceptance of evolution in America, then, may have to await profound social change. © 2012 The Author(s). Evolution© 2012 The Society for the Study of Evolution.

  17. Control of norovirus outbreak on a pediatric oncology unit.

    PubMed

    Sheahan, Anna; Copeland, Gretchen; Richardson, Lauren; McKay, Shelley; Chou, Alexander; Babady, N Esther; Tang, Yi-Wei; Boulad, Farid; Eagan, Janet; Sepkowitz, Kent; Kamboj, Mini

    2015-10-01

    Patients undergoing treatment for cancer with chemotherapy and hematopoietic stem cell recipients are at risk for severe morbidity caused by norovirus (NV). We describe a NV outbreak on the Memorial Sloan Kettering Cancer Center's pediatric oncology unit. Stool testing for diagnosis of NV was performed by real-time polymerase chain reaction (PCR). Twelve NV cases occurred; 7 were hospital acquired. Twenty-five health care workers reported NV compatible illness. Patient-to-patient transmission occurred once. The practices of the Centers for Disease Control and Prevention were supplemented with electronic surveillance, surrogate screening for NV, and heightened cleaning. Two additional cases occurred after implementation of interventions. Long-term shedding was detected in 2 patients. We describe interventions for controlling NV on a pediatric oncology unit. High-risk chronic shedders pose ongoing transmission risks. PCR is a valuable diagnostic tool but may be overly sensitive. Surrogate markers to assess NV burden in stool and studies on NV screening are needed to develop guidelines for high-risk chronic shedders. Copyright © 2015 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  18. Solar energy development impacts on land cover change and protected areas

    PubMed Central

    Hernandez, Rebecca R.; Hoffacker, Madison K.; Murphy-Mariscal, Michelle L.; Wu, Grace C.; Allen, Michael F.

    2015-01-01

    Decisions determining the use of land for energy are of exigent concern as land scarcity, the need for ecosystem services, and demands for energy generation have concomitantly increased globally. Utility-scale solar energy (USSE) [i.e., ≥1 megawatt (MW)] development requires large quantities of space and land; however, studies quantifying the effect of USSE on land cover change and protected areas are limited. We assessed siting impacts of >160 USSE installations by technology type [photovoltaic (PV) vs. concentrating solar power (CSP)], area (in square kilometers), and capacity (in MW) within the global solar hot spot of the state of California (United States). Additionally, we used the Carnegie Energy and Environmental Compatibility model, a multiple criteria model, to quantify each installation according to environmental and technical compatibility. Last, we evaluated installations according to their proximity to protected areas, including inventoried roadless areas, endangered and threatened species habitat, and federally protected areas. We found the plurality of USSE (6,995 MW) in California is sited in shrublands and scrublands, comprising 375 km2 of land cover change. Twenty-eight percent of USSE installations are located in croplands and pastures, comprising 155 km2 of change. Less than 15% of USSE installations are sited in “Compatible” areas. The majority of “Incompatible” USSE power plants are sited far from existing transmission infrastructure, and all USSE installations average at most 7 and 5 km from protected areas, for PV and CSP, respectively. Where energy, food, and conservation goals intersect, environmental compatibility can be achieved when resource opportunities, constraints, and trade-offs are integrated into siting decisions. PMID:26483467

  19. Is passenger vehicle incompatibility still a problem?

    PubMed

    Teoh, Eric R; Nolan, Joseph M

    2012-01-01

    Passenger cars often are at a disadvantage when colliding with light trucks (sport utility vehicles [SUVs] and pickups) due to differences in mass, vehicle structural alignment, and stiffness. In 2003, vehicle manufacturers agreed to voluntary measures to improve compatibility, especially in front-to-front and front-to-side crashes, with full adherence to be achieved by September 2009. This study examined whether fatality rates are consistent with the expected benefit of this agreement. Analyses examined 2 death rates for 1- to 4-year-old passenger vehicles during 2000-2001 and 2008-2009 in the United States: occupant deaths per million registered vehicle years in these vehicles and deaths in other cars that collided with these vehicles in 2-vehicle crashes per million registered vehicle years. These rates were computed for each study period and for cars/minivans (referred to as cars), SUVs, and pickups by curb weight (in 500-pound increments). The latter death rate, referred to as the car crash partner death rate, also was computed for front-to-front crashes and front-to-side crashes where the front of the 1- to 4-year-old vehicle struck the side of the partner car. In both study periods, occupant death rates generally decreased for each vehicle type both with increasing curb weight and over time. SUVs experienced the greatest declines compared with cars and pickups. This is due in part to the early fitment of electronic stability control in SUVs, which drastically reduced the incidence of single-vehicle rollover crashes. Pickups had the highest death rates in both study periods. Car crash partner death rates generally declined over time for all vehicle categories but more steeply for SUVs and pickups colliding with cars than for cars colliding with cars. In fact, the car crash partner death rates for SUVs and cars were nearly identical during 2008-2009, suggesting that the voluntary design changes for compatibility have been effective. Car crash partner death rates also declined for pickups, but their rates were consistently the highest in both study periods. It is impossible to disentangle the individual contributions of the compatibility agreement, improved crashworthiness of cars, and other factors in reducing car crash partner fatality rates. However, the generally larger reductions in car crash partner death rates for SUVs and pickups indicate the likely benefits of the agreement. Overall, this study finds that the system of regulatory testing, voluntary industry initiatives, and consumer information testing has led to a passenger vehicle fleet that is much more compatible in crashes.

  20. Pooling job physical exposure data from multiple independent studies in a consortium study of carpal tunnel syndrome

    PubMed Central

    Kapellusch, Jay M.; Garg, Arun; Bao, Stephen S.; Silverstein, Barbara A.; Burt, Susan E.; Dale, Ann Marie; Evanoff, Bradley A.; Gerr, Frederic E.; Harris-Adamson, Carisa; Hegmann, Kurt T.; Merlino, Linda A.; Rempel, David M.

    2015-01-01

    Pooling data from different epidemiological studies of musculoskeletal disorders (MSDs) is necessary to improve statistical power and to more precisely quantify exposure–response relationships for MSDs. The pooling process is difficult and time-consuming, and small methodological differences could lead to different exposure–response relationships. A subcommittee of a six-study research consortium studying carpal tunnel syndrome: (i) visited each study site, (ii) documented methods used to collect physical exposure data and (iii) determined compatibility of exposure variables across studies. Certain measures of force, frequency of exertion and duty cycle were collected by all studies and were largely compatible. A portion of studies had detailed data to investigate simultaneous combinations of force, frequency and duration of exertions. Limited compatibility was found for hand/wrist posture. Only two studies could calculate compatible Strain Index scores, but Threshold Limit Value for Hand Activity Level could be determined for all studies. Challenges of pooling data, resources required and recommendations for future researchers are discussed. PMID:23697792

  1. Lignocellulosic feedstock resource assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rooney, T.

    This report provides overall state and national information on the quantity, availability, and costs of current and potential feedstocks for ethanol production in the United States. It characterizes end uses and physical characteristics of feedstocks, and presents relevant information that affects the economic and technical feasibility of ethanol production from these feedstocks. The data can help researchers focus ethanol conversion research efforts on feedstocks that are compatible with the resource base.

  2. Experimental Results of an Electrostatic Injector

    DTIC Science & Technology

    2014-10-01

    is important especially in the realm of biofuels . In the long term, the United States Department of Defense (DOD) is interested in converting many...of their vehicles to biofuels . Both the U.S. Army and Navy have invested substantially into research pertaining to converting existing fleets to... biofuel compatibility. The recent work of Owkes and Desjardins has investigated the effects of electrostatic spray with biofuels [11]. They

  3. Prototype Slide Stainer

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The prototype slide staining system capable of performing both one-component Wright's staining of blood smears and eight-step Gram staining of heat fixed slides of microorganisms is described. Attention was given to liquid containment, waste handling, absence of contamination from previous staining, and stability of the staining reagents. The unit is self-contained, capable of independent operation under one- or zero-g conditions, and compatible with Skylab A.

  4. Building Systems Information Clearinghouse Special Report Number One: Manufacturers Compatibility Study.

    ERIC Educational Resources Information Center

    Boice, John R., Ed.

    BSIC has selected data for inclusion, and a method of presentation that-- (1) provides preliminary data, in comparable form, about all relevant systems building products, (2) surveys within the limits imposed, the problems of compatibility between subsystem components and to identify components which are compatible with one another, (3) identifies…

  5. N2pc is modulated by stimulus-stimulus, but not by stimulus-response incompatibilities.

    PubMed

    Cespón, J; Galdo-Álvarez, S; Díaz, F

    2013-04-01

    Studies of the N2pc in Simon-type tasks have revealed inconsistent results. That is, N2pc was only modulated when a stimulus-stimulus (S-S) overlap covaries with the stimulus-response (S-R) overlap. The present study aimed to establish whether N2pc is modulated by the S-R or by the S-S overlap. Therefore, we designed a Simon task requiring response to a colour stimulus (an arrow) with two irrelevant dimensions (position and direction). The following conditions were thus generated: compatible direction-compatible position (CDCP); incompatible direction-compatible position (IDCP); compatible direction-incompatible position (CDIP); and incompatible direction-incompatible position (IDIP). In IDCP and CDIP, both irrelevant dimensions conveyed contradictory spatial information (S-S incompatibility), while compatibility between both irrelevant dimensions occurred in CDCP and IDIP (the direction indicated was compatible with stimulus position). The N2pc amplitude was smaller in IDCP and CDIP than in CDCP and IDIP, what suggests that N2pc was modulated by S-S incompatibility and not by S-R incompatibilities. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Which ureteral access sheath is compatible with your flexible ureteroscope?

    PubMed

    Al-Qahtani, Saeed M; Letendre, Julien; Thomas, Alexandre; Natalin, Ricardo; Saussez, Thibaud; Traxer, Olivier

    2014-03-01

    Our aim is to evaluate different ureteral access sheaths (UASs), which are available in the international market and their compatibility with different available flexible ureteroscopes (F-URSs) to help the urologist choose the proper ureteral access sheath for his or her endoscope before commencing the procedure. A total of 21 UASs and 12 F-URSs were evaluated. Measurements were obtained in French (F) units considering different characteristics for each UAS and each F-URS. Insertion test without friction between F-URS and UAS was considered as a successful test and was referred as (YES). All UASs and F-URSs were successfully submitted to the insertion test. All F-URSs that were inserted into UASs without friction had an internal diameter of at least 12F. Different lengths of UAS did not influence the test outcome. This study was able to establish a correlation table between different UASs and different flexible ureteroscopes. As of now, the 12/14F UAS is considered the universal UAS that accepts all F-URSs that are available in the endourology field. Nevertheless, we are expecting a significant change with the new standard size 10/12F UAS as well as huge advances in minimizing the size of different endoscopes.

  7. Preparation of red blood cell concentrates and plasma units from whole blood held overnight using a hollow-fibre separation system.

    PubMed

    Johnson, L; Kwok, M; Marks, D C

    2015-02-01

    The ErySep system represents an alternative to centrifuge-based whole blood (WB) separation, using gravity and filtration through hollow-fibres (0·2 µm pore size) to produce red blood cell (RBC) and plasma components. The aim of this study was to characterise the quality of ErySep RBC and plasma units compared with standard products from WB held overnight. Two ABO-compatible WB units (n = 24) were pooled and split to produce matched products. One of the WB units was separated into components using the ErySep system (ErySep; n = 12), whereas the other units were separated by centrifugation (control; n = 12). RBC units were stored at 2-6 °C and assessed for in vitro quality over 42 days of storage. Plasma was frozen at -30 °C and tested upon thawing. Processing WB with the ErySep system took longer than controls. The ErySep RBC units were of an appropriate volume (307 ± 17 mL) and contained sufficient Hb (50 ± 2 g unit(-1) ). ErySep RBC components contained more microparticles relative to controls at expiry. The plasma volume, total protein, coagulation factor activity (fibrinogen, FV, FVIII) and number of microparticles was lower in the ErySep units compared with controls. Following overnight hold of WB, the ErySep system was capable of producing RBC components that met specifications. However, the ErySep plasma components did not meet quality specifications. © 2015 British Blood Transfusion Society.

  8. Preferential distribution of nociceptive input to motoneurons with muscle units in the cranial portion of the upper trapezius muscle.

    PubMed

    Dideriksen, Jakob L; Holobar, Ales; Falla, Deborah

    2016-08-01

    Pain is associated with changes in the neural drive to muscles. For the upper trapezius muscle, surface electromyography (EMG) recordings have indicated that acute noxious stimulation in either the cranial or the caudal region of the muscle leads to a relative decrease in muscle activity in the cranial region. It is, however, not known if this adaption reflects different recruitment thresholds of the upper trapezius motor units in the cranial and caudal region or a nonuniform nociceptive input to the motor units of both regions. This study investigated these potential mechanisms by direct motor unit identification. Motor unit activity was investigated with high-density surface EMG signals recorded from the upper trapezius muscle of 12 healthy volunteers during baseline, control (intramuscular injection of isotonic saline), and painful (hypertonic saline) conditions. The EMG was decomposed into individual motor unit spike trains. Motor unit discharge rates decreased significantly from control to pain conditions by 4.0 ± 3.6 pulses/s (pps) in the cranial region but not in the caudal region (1.4 ± 2.8 pps; not significant). These changes were compatible with variations in the synaptic input to the motoneurons of the two regions. These adjustments were observed, irrespective of the location of noxious stimulation. These results strongly indicate that the nociceptive synaptic input is distributed in a nonuniform way across regions of the upper trapezius muscle. Copyright © 2016 the American Physiological Society.

  9. Preferential distribution of nociceptive input to motoneurons with muscle units in the cranial portion of the upper trapezius muscle

    PubMed Central

    Dideriksen, Jakob L.; Holobar, Ales

    2016-01-01

    Pain is associated with changes in the neural drive to muscles. For the upper trapezius muscle, surface electromyography (EMG) recordings have indicated that acute noxious stimulation in either the cranial or the caudal region of the muscle leads to a relative decrease in muscle activity in the cranial region. It is, however, not known if this adaption reflects different recruitment thresholds of the upper trapezius motor units in the cranial and caudal region or a nonuniform nociceptive input to the motor units of both regions. This study investigated these potential mechanisms by direct motor unit identification. Motor unit activity was investigated with high-density surface EMG signals recorded from the upper trapezius muscle of 12 healthy volunteers during baseline, control (intramuscular injection of isotonic saline), and painful (hypertonic saline) conditions. The EMG was decomposed into individual motor unit spike trains. Motor unit discharge rates decreased significantly from control to pain conditions by 4.0 ± 3.6 pulses/s (pps) in the cranial region but not in the caudal region (1.4 ± 2.8 pps; not significant). These changes were compatible with variations in the synaptic input to the motoneurons of the two regions. These adjustments were observed, irrespective of the location of noxious stimulation. These results strongly indicate that the nociceptive synaptic input is distributed in a nonuniform way across regions of the upper trapezius muscle. PMID:27226455

  10. SU-F-J-172: Hybrid MR/CT Compatible Phantom for MR-Only Based Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, M; Lee, S; Song, K

    2016-06-15

    Purpose: Development of hybrid MR/CT compatible phantom was introduced to fully establish MR image only radiation treatment and this suggested technique using in-house developed hybrid MR/CT compatible phantom image would utilize to generate radiation treatment planning and perform dose calculation without multi-modal registration process or generation of pseudo CT. Methods: Fundamental characteristics for “hybrid MR/CT compatible phantom” was established: Relaxation times equivalent to human tissue, dielectric properties, homogeneous relaxation times, sufficient strength to fabricate a torso, ease of handling, a wide variety of density material for calibration, chemical and physical stability over an extended time. For this requirements, chemical componentmore » in each tested plug which would be tissue equivalent to human tissue on MR and CT image and production of phantom body and plug was performed. Chemical component has described below: Agaros, GdCl{sub 3}, NaN{sub 3}, NaCl, K{sub 2}Co{sub 3}, deionized-distilled water. Various mixture of chemical component to simulate human tissue on both MR and CT image was tested by measuring T1, T2 relaxation time and signal intensity (SI) on MR image and Hounsfield unit (HU) on CT and each value was compared. The hybrid MR/CT compatible phantom with 14 plugs was designed and has made. Total height and external diameter was decided by internal size of 32 channel MR head-coil. Results: Tissue-equivalent chemical component materials and hybrid MR/CT compatible phantom was developed. The range of T1, T2 relaxation time and SI on MR image, HU on CT was acquired and could be adjusted to correspond to simulated human tissue. Conclusion: Current result shows its possibility for MR-only based radiotherapy and the best mixing rate of chemical component for tissue-equivalent image on MR and CT was founded. However, additional technical issues remain to be overcome. Conversion of SI on MR image into HU and dose calculation based on converted MRI will be progressing.« less

  11. Algebraic and geometric structures of analytic partial differential equations

    NASA Astrophysics Data System (ADS)

    Kaptsov, O. V.

    2016-11-01

    We study the problem of the compatibility of nonlinear partial differential equations. We introduce the algebra of convergent power series, the module of derivations of this algebra, and the module of Pfaffian forms. Systems of differential equations are given by power series in the space of infinite jets. We develop a technique for studying the compatibility of differential systems analogous to the Gröbner bases. Using certain assumptions, we prove that compatible systems generate infinite manifolds.

  12. Breeding graft-compatible Douglas-fir rootstocks (Pseudotsuga menziesii (Mirb.) Franco).

    Treesearch

    D.L. Copes

    1999-01-01

    A study encompassing 24 years was conducted to determine if a breeding program could produce highly graft-compatible rootstocks. Twenty-seven trees of apparent high graft compatibility were selected and crossed to produce 226 control-pollinated families. Seedlings were grown, field planted, and grafted with test scions. Graft unions from field tests were evaluated...

  13. Digital geologic map and GIS database of Venezuela

    USGS Publications Warehouse

    Garrity, Christopher P.; Hackley, Paul C.; Urbani, Franco

    2006-01-01

    The digital geologic map and GIS database of Venezuela captures GIS compatible geologic and hydrologic data from the 'Geologic Shaded Relief Map of Venezuela,' which was released online as U.S. Geological Survey Open-File Report 2005-1038. Digital datasets and corresponding metadata files are stored in ESRI geodatabase format; accessible via ArcGIS 9.X. Feature classes in the geodatabase include geologic unit polygons, open water polygons, coincident geologic unit linework (contacts, faults, etc.) and non-coincident geologic unit linework (folds, drainage networks, etc.). Geologic unit polygon data were attributed for age, name, and lithologic type following the Lexico Estratigrafico de Venezuela. All digital datasets were captured from source data at 1:750,000. Although users may view and analyze data at varying scales, the authors make no guarantee as to the accuracy of the data at scales larger than 1:750,000.

  14. A Self-Referenced Optical Intensity Sensor Network Using POFBGs for Biomedical Applications

    PubMed Central

    Moraleda, Alberto Tapetado; Montero, David Sánchez; Webb, David J.; García, Carmen Vázquez

    2014-01-01

    This work bridges the gap between the remote interrogation of multiple optical sensors and the advantages of using inherently biocompatible low-cost polymer optical fiber (POF)-based photonic sensing. A novel hybrid sensor network combining both silica fiber Bragg gratings (FBG) and polymer FBGs (POFBG) is analyzed. The topology is compatible with WDM networks so multiple remote sensors can be addressed providing high scalability. A central monitoring unit with virtual data processing is implemented, which could be remotely located up to units of km away. The feasibility of the proposed solution for potential medical environments and biomedical applications is shown. PMID:25615736

  15. A self-referenced optical intensity sensor network using POFBGs for biomedical applications.

    PubMed

    Tapetado Moraleda, Alberto; Sánchez Montero, David; Webb, David J; Vázquez García, Carmen

    2014-12-12

    This work bridges the gap between the remote interrogation of multiple optical sensors and the advantages of using inherently biocompatible low-cost polymer optical fiber (POF)-based photonic sensing. A novel hybrid sensor network combining both silica fiber Bragg gratings (FBG) and polymer FBGs (POFBG) is analyzed. The topology is compatible with WDM networks so multiple remote sensors can be addressed providing high scalability. A central monitoring unit with virtual data processing is implemented, which could be remotely located up to units of km away. The feasibility of the proposed solution for potential medical environments and biomedical applications is shown.

  16. ERTS data user investigation to develop a multistage forest sampling inventory system

    NASA Technical Reports Server (NTRS)

    Langley, P. G.; Vanroessel, J. W. (Principal Investigator); Wert, S. L.

    1973-01-01

    The author has identified the following significant results. A system to provide precision annotation of predetermined forest inventory sampling units on the ERTS-1 MSS images was developed. In addition, an annotation system for high altitude U2 photographs was completed. MSS bulk image accuracy is good enough to allow the use of one square mile sampling units. IMANCO image analyzer interpretation work for small scale images demonstrated the need for much additional analyses. Continuing image interpretation work for the next reporting period is concentrated on manual image interpretation work as well as digital interpretation system development using the computer compatible tapes.

  17. Evolution of Compatibility Range in the Rice-Magnaporthe oryzae System: An Uneven Distribution of R Genes Between Rice Subspecies.

    PubMed

    Gallet, Romain; Fontaine, Colin; Bonnot, François; Milazzo, Joëlle; Tertois, Christophe; Adreit, Henri; Ravigné, Virginie; Fournier, Elisabeth; Tharreau, Didier

    2016-04-01

    Efficient strategies for limiting the impact of pathogens on crops require a good understanding of the factors underlying the evolution of compatibility range for the pathogens and host plants, i.e., the set of host genotypes that a particular pathogen genotype can infect and the set of pathogen genotypes that can infect a particular host genotype. Until now, little is known about the evolutionary and ecological factors driving compatibility ranges in systems implicating crop plants. We studied the evolution of host and pathogen compatibility ranges for rice blast disease, which is caused by the ascomycete Magnaporthe oryzae. We challenged 61 rice varieties from three rice subspecies with 31 strains of M. oryzae collected worldwide from all major known genetic groups. We determined the compatibility range of each plant variety and pathogen genotype and the severity of each plant-pathogen interaction. Compatibility ranges differed between rice subspecies, with the most resistant subspecies selecting for pathogens with broader compatibility ranges and the least resistant subspecies selecting for pathogens with narrower compatibility ranges. These results are consistent with a nested distribution of R genes between rice subspecies.

  18. Multimission Modular Spacecraft Ground Support Software System (MMS/GSSS) state-of-the-art computer systems/ compatibility study

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The compatibility of the Multimission Modular Spacecraft (MMS) Ground Support Software System (GSSS), currently operational on a ModComp IV/35, with the VAX 11/780 system is discussed. The compatibility is examined in various key areas of the GSSS through the results of in depth testing performed on the VAX 11/780 and ModComp IV/35 systems. The compatibility of the GSSS with the ModComp CLASSIC is presented based upon projections from ModComp supplied literature.

  19. Empirical study of fuzzy compatibility measures and aggregation operators

    NASA Astrophysics Data System (ADS)

    Cross, Valerie V.; Sudkamp, Thomas A.

    1992-02-01

    Two fundamental requirements for the generation of support using incomplete and imprecise information are the ability to measure the compatibility of discriminatory information with domain knowledge and the ability to fuse information obtained from disparate sources. A generic architecture utilizing the generalized fuzzy relational database model has been developed to empirically investigate the support generation capabilities of various compatibility measures and aggregation operators. This paper examines the effectiveness of combinations of compatibility measures from the set-theoretic, geometric distance, and logic- based classes paired with t-norm and generalized mean families of aggregation operators.

  20. Thermodynamic analysis of chemical compatibility of several reinforcement materials with niobium aluminides

    NASA Technical Reports Server (NTRS)

    Misra, Ajay K.

    1989-01-01

    Chemical compatibility of several reinforcement materials with three niobium aluminides, Nb3Al, Nb2Al, and NbAl3, were examined from thermodynamic considerations. The reinforcement materials considered in this study include carbides, borides, nitrides, oxides, silicides, and Engel-Brewer compounds. Thermodynamics of the Nb-Al system were reviewed and activities of Nb and Al were derived at desired calculation temperatures. Criteria for chemical compatibility between the reinforcement material and Nb-Al compounds have been defined and several chemically compatible reinforcement materials have been identified.

  1. The development of new, low-cost perfluoroalkylether fluids with excellent low and high-temperature properties

    NASA Technical Reports Server (NTRS)

    Bierschenk, Thomas R.; Kawa, Hajimu; Juhlke, Timothy J.; Lagow, Richard J.

    1988-01-01

    A series of perfluoroalkylether (PFAE) fluids were synthesized by direct fluorination. Viscosity-temperature properties, oxidation stabilities, oxidation-corrosion properties, and lubricity were determined. The fluids were tested in the presence of common elastomers to check for compatibility. The bulk modulus of each was measured to determine if any could be used as nonflammable aircraft hydraulic fluid. It was determined that as the carbon to oxygen ratio decreases, the viscometric properties improve, the fluids may become poor lubricants, the bulk modulus increases, the surface tension increases, and the fluid density increases. The presence of difluoromethylene oxide units in the polymer does not seriously lower the oxidation and oxidation-corrosion stabilities as long as the difluoromethylene oxide units are separated by other units.

  2. Dual-task performance with ideomotor-compatible tasks: is the central processing bottleneck intact, bypassed, or shifted in locus?

    NASA Technical Reports Server (NTRS)

    Lien, Mei-Ching; McCann, Robert S.; Ruthruff, Eric; Proctor, Robert W.

    2005-01-01

    The present study examined whether the central bottleneck, assumed to be primarily responsible for the psychological refractory period (PRP) effect, is intact, bypassed, or shifted in locus with ideomotor (IM)-compatible tasks. In 4 experiments, factorial combinations of IM- and non-IM-compatible tasks were used for Task 1 and Task 2. All experiments showed substantial PRP effects, with a strong dependency between Task 1 and Task 2 response times. These findings, along with model-based simulations, indicate that the processing bottleneck was not bypassed, even with two IM-compatible tasks. Nevertheless, systematic changes in the PRP and correspondence effects across experiments suggest that IM compatibility shifted the locus of the bottleneck. The findings favor an engage-bottleneck-later hypothesis, whereby parallelism between tasks occurs deeper into the processing stream for IM- than for non-IM-compatible tasks, without the bottleneck being actually eliminated.

  3. New advances in MR-compatible bioartificial liver

    PubMed Central

    Jeffries, Rex E.; Macdonald, Jeffrey M.

    2015-01-01

    MR-compatible bioartificial liver (BAL) studies have been performed for 30 years and are reviewed. There are two types of study: (i) metabolism and drug studies using multinuclear MRS; primarily short-term (< 8 h) studies; (ii) the use of multinuclear MRS and MRI to noninvasively define the features and functions of BAL systems for long-term liver tissue engineering. In the latter, these systems often undergo not only modification of the perfusion system, but also the construction of MR radiofrequency probes around the bioreactor. We present novel MR-compatible BALs and the use of multinuclear MRS (13C, 19F, 31P) for the noninvasive monitoring of their growth, metabolism and viability, as well as 1H MRI methods for the determination of flow profiles, diffusion, cell distribution, quality assurance and bioreactor integrity. Finally, a simple flexible coil design and circuit, and life support system, are described that can make almost any BAL MR-compatible. PMID:22351642

  4. An experimental study on the compatibility of acetone with aluminum flat-plate heat pipes

    NASA Astrophysics Data System (ADS)

    Hsieh, Jui-Ching; Lin, David T. W.; Huang, Hsin-Jung; Yang, Tzu-Wei

    2014-04-01

    This study investigates the compatibility of aluminum flat-plate heat pipes (FPHPs) used for filling acetone as a working fluid after long-term operation of and the non-condensable gas (NCG) exhausting process. The rate of NCG generation substantially decreased after conducting the NCG exhausting process, proving the compatibility of acetone with the aluminum FPHPs. However, the thermal resistance was not enhanced because hydroxide bayerite (Al(OH)3) was generated as a product of the reaction.

  5. Imide/arylene ether copolymers

    NASA Technical Reports Server (NTRS)

    Jensen, Brian J. (Inventor); Hergenrother, Paul M. (Inventor); Bass, Robert G. (Inventor)

    1992-01-01

    Imide/arylene ether block copolymers are prepared by reacting anhydride terminated poly(amic acids) with amine terminated poly(arylene ethers) in polar aprotic solvents and by chemically or thermally cyclodehydrating the resulting intermediate poly(amic acids). The resulting block copolymers have one glass transition temperature or two, depending upon the particular structure and/or the compatibility of the block units. Most of these block copolymers form tough, solvent resistant films with high tensile properties.

  6. Policy Options to Address Crucial Communication Gaps in the Incident Command System

    DTIC Science & Technology

    2012-09-01

    California Department of Forestry and Fire Protection COML Communications Unit Leader COMT Communication Technician EBRPD East Bay Regional Parks...Laguna Fire 1970 - One of California’s Worst Wildfires.” Available at http://www.cccarto.com/cal_wildfire/laguna/fire.html, Accessed August 10, 2012...NIMS - The Evolution of the National Incident Management System.” Fire Rescue Magazine, August 2011. 15 compatibility, and department emergency

  7. The Phase of Illness Paradigm: A Checklist Centric Model to Improve Patient Care in the Burn Intensive Care Unit

    DTIC Science & Technology

    2016-04-01

    oxygenation and ventilation Goal Adequate oxygenation and/or ventilation Goal Skin grafting Objective Surgical operation (implicit goal = achieve...Abdominal Pressures, [TTE/IVC measurement] Assure effective Ventilation & Sedation (Standard ICU) EtCO2, A-Line, ±CVP 4E Compatible Decrease...commands) Participatory (expresses self)  minimize oxygen demand  maximize perfusion  protect grafts  patient ventilator

  8. Mechanical engineering and design criteria for the Magnetically Insulated Transmission Experiment Accelerator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Staller, G.E.; Hamilton, I.D.; Aker, M.F.

    1978-02-01

    A single-unit electron beam accelerator was designed, fabricated, and assembled in Sandia's Technical Area V to conduct magnetically insulated transmission experiments. Results of these experiments will be utilized in the future design of larger, more complex accelerators. This design makes optimum use of existing facilities and equipment. When designing new components, possible future applications were considered as well as compatibility with existing facilities and hardware.

  9. Analysis of dose-incidence relationships for marrow failure in different species, in terms of radiosensitivity of tissue-rescuing units

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hendry, J.H.; Roberts, S.A.

    1990-05-01

    The analysis of 68 published sets of dose-incidence data for marrow failure in different species, using a double-log mortality function, indicates: (a) There is more heterogeneity, i.e. greater sums-of-squares per degree of freedom, within the data sets for mouse than for larger species (monkey, dog, sheep, goat, pig). (b) For mice the curves for acute doses are characterized by a D0 of about 100 cGy for tissue-rescuing units (or target cells), which are depleted at most to about 3 x 10(-4) at LD50. (c) Larger species are much less tolerant to target-cell depletion, the corresponding level being consistently in themore » range of 10(-2)-10(-3) at LD50. Also, the D0 is often lower (approximately 55 cGy), which is compatible in the dog with such a value for hemopoietic progenitor cells. (d) With larger species there is an unexpected reduction in heterogeneity when the dose rate is lower, which gives a D0 lower than expected and a higher extrapolate. It is concluded that the position and slope of the dose-incidence curves are compatible with interpretations based primarily on target-cell number and survival characteristics, modified by additional heterogeneity factors.« less

  10. Vacuum Compatibility of Laser-Sintered Metals

    NASA Astrophysics Data System (ADS)

    Rivera, W. F.; Romero-Talamas, C. A.; Bates, E. M.; Birmingham, W. J.; Quinley, M.; Woodruff, S.; Stuber, J. E.; Sieck, P. E.; Melnik, P. A.

    2016-10-01

    We present the design and results of a mass spectrometry system used to assess vacuum compatibility of selective laser-sintered parts. The parts are disks with a thickness of 0.20 cm and a diameter of 8.25 cm, and are made of aluminum, stainless steel, inconel, and titanium. From preliminary results, titanium had the lowest partial pressure for hydrogen. Outgassing from laser-sintered parts is compared against parts with similar surface area that are manufactured with traditional methods. Outgassing is also measured while the part is heated, emulating the conditions at the edge of high temperature plasma confinement chambers. Each part is placed on a heated container that can vary in temperature inside the mass spectrometer's vacuum chamber. The partial pressures of elements up to 200 atomic mass units are analyzed to obtain outgassing data from each sample. This work supported under DOE SBIR Grant DE SC0011858.

  11. Site-Specific Protein Labeling via Sortase-Mediated Transpeptidation

    PubMed Central

    Antos, John M.; Ingram, Jessica; Fang, Tao; Pishesha, Novalia; Truttmann, Matthias C.; Ploegh, Hidde L.

    2017-01-01

    Strategies for site-specific protein modification are highly desirable for the construction of conjugates containing non-genetically encoded functional groups. Ideally, these strategies should proceed under mild conditions, and be compatible with a wide range of protein targets and non-natural moieties. The transpeptidation reaction catalyzed by bacterial sortases is a prominent strategy for protein derivatization that possesses these features. Naturally occurring or engineered variants of sortase A from Staphylococcus aureus catalyze a ligation reaction between a five amino acid substrate motif (LPXTG) and oligoglycine nucleophiles. By pairing proteins and synthetic peptides that possess these ligation handles, it is possible to install modifications onto the protein N- or C-terminus in site-specific fashion. As described in this unit, the successful implementation of sortase-mediated labeling involves straightforward solid-phase synthesis and molecular biology techniques, and this method is compatible with proteins in solution or on the surface of live cells. PMID:19365788

  12. Flexible organic tandem solar modules: a story of up-scaling

    NASA Astrophysics Data System (ADS)

    Spyropoulos, George D.; Kubis, Peter; Li, Ning; Lucera, Luca; Salvador, Michael; Baran, Derya; Machui, Florian; Ameri, Tayebeh; Voigt, Monika M.; Brabec, Christoph J.

    2014-10-01

    The competition in the field of solar energy between Organic Photovoltaics (OPVs) and several Inorganic Photovoltaic technologies is continuously increasing to reach the ultimate purpose of energy supply from inexpensive and easily manufactured solar cell units. Solution-processed printing techniques on flexible substrates attach a tremendous opportunity to the OPVs for the accomplishment of low-cost and large area applications. Furthermore, tandem architectures came to boost up even more OPVs by increasing the photon-harvesting properties of the device. In this work, we demonstrate the road of realizing flexible organic tandem solar modules constructed by a fully roll-to-roll compatible processing. The modules exhibit an efficiency of 5.4% with geometrical fill factors beyond 80% and minimized interconnection-resistance losses. The processing involves low temperature (<70 °C), coating methods compatible with slot die coating and high speed and precision laser patterning.

  13. Electrically Conductive and Protective Coating for Planar SOFC Stacks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choi, Jung-Pyung; Stevenson, Jeffry W.

    Ferritic stainless steels are preferred interconnect materials for intermediate temperature SOFCs because of their resistance to oxidation, high formability and low cost. However, their protective oxide layer produces Cr-containing volatile species at SOFC operating temperatures and conditions, which can cause cathode poisoning. Electrically conducting spinel coatings have been developed to prevent cathode poisoning and to maintain an electrically conductive pathway through SOFC stacks. However, this coating is not compatible with the formation of stable, hermetic seals between the interconnect frame component and the ceramic cell. Thus, a new aluminizing process has been developed by PNNL to enable durable sealing, preventmore » Cr evaporation, and maintain electrical insulation between stack repeat units. Hence, two different types of coating need to have stable operation of SOFC stacks. This paper will focus on the electrically conductive coating process. Moreover, an advanced coating process, compatible with a non-electrically conductive coating will be« less

  14. Nodular mucinosis misdiagnosed as non-responsive secondary syphilis

    PubMed Central

    Patrício, Catarina; Campos, Sara; João, Alexandre; Serrão, Vasco

    2015-01-01

    A previously healthy 24-year-old man presented with an erythematous, non-pruritic and painless papulonodular skin rash affecting the trunk, upper arms (excluding palms), neck, face, forehead and scalp. He had a penile ulcer for the past 2 weeks, almost healed at the time of observation. The patient tested positive for syphilis and HIV-1; he claimed being negative for HIV 6 months earlier. As the palms were not affected, we performed a skin biopsy for the differential diagnosis between secondary lues and acute HIV seroconversion reaction. Benzathine penicillin (2 400 000 units) was administrated and antiretroviral therapy started. Although the skin biopsy was compatible with secondary syphilis, there was no change in the skin rash 3 weeks after the first penicillin administration. Another 2 doses of penicillin were given but 4 weeks later the rash persisted. A second biopsy revealed a mucinous skin infiltration, compatible with nodular mucinosis. PMID:26311009

  15. Military applications of emission and susceptibility data

    NASA Astrophysics Data System (ADS)

    Kohlbacher, Howard; Walker, William

    A basic design consideration for new military communications-electronics (C-E) equipment is that it be electromagnetically compatible with the environment in which it will operate. A military standard (MIL-STD-461B) describes the design requirements for the control of the unintentional electromagnetic emission and susceptibility characteristics of electronic equipment and subsystems designed or procured by the US Department of Defense. For new systems which fail the test standards of MIL-STD-461B with regard to radiated susceptibility (RSO3) or radiated emissions (RE02), a decision must be made to fix the new system or to field it without a fix. A procedure to aid in the decision process is outlined. The minimum separation distances required between a failed test system and other C-E equipment in its environment to avoid interference are determined. If this distance is operationally acceptable, the failed unit may be considered to be operationally compatible with its electromagnetic environment.

  16. Advanced Reconnaissance System Component Reliability Study

    DTIC Science & Technology

    1956-07-31

    dielectrics. Gaseous dielectrics such as sulphur hexafluoride and ’ fluorocarbons at two to three atmospheres. Fluorinated liquid dielectrics. 3) The...limits. (2) determine compatibility with varnish treatments, (3) compatibility in a complete insulation system. Mechanical and thermal limits of...of a varnish to have good • adhersion, provide an element of flexibility and be chemically compatible with’the wire it is impregnating.. Factors of

  17. Obsessive-compulsive tendencies are associated with a focused information processing strategy.

    PubMed

    Soref, Assaf; Dar, Reuven; Argov, Galit; Meiran, Nachshon

    2008-12-01

    The study examined the hypothesis that obsessive-compulsive (OC) tendencies are related to a reliance on focused and serial rather than a parallel, speed-oriented information processing style. Ten students with high OC tendencies and 10 students with low OC tendencies performed the flanker task, in which they were required to quickly classify a briefly presented target letter (S or H) that was flanked by compatible (e.g., SSSSS) or incompatible (e.g., HHSHH) noise letters. Participants received 4 blocks of 100 trials each, two with 50% compatible trials and two with 80% compatible trials and were informed of the probability of compatible trials before the beginning of each block. As predicted, high OC participants, as compared to low OC participants, had slower overall reaction time (RT) and lower tendency for parallel processing (defined as incompatible trials RT minus compatible trials RT). Low, more than high OC participants tended to adjust their focused/parallel processing including a shift towards parallel processing in blocks with 80% compatible trials and in trials following compatible trials. Implications of these results to the cognitive theory and therapy of OCD are discussed.

  18. Unstable identity compatibility: how gender rejection sensitivity undermines the success of women in science, technology, engineering, and mathematics fields.

    PubMed

    Ahlqvist, Sheana; London, Bonita; Rosenthal, Lisa

    2013-09-01

    Although the perceived compatibility between one's gender and science, technology, engineering, and mathematics (STEM) identities (gender-STEM compatibility) has been linked to women's success in STEM fields, no work to date has examined how the stability of identity over time contributes to subjective and objective STEM success. In the present study, 146 undergraduate female STEM majors rated their gender-STEM compatibility weekly during their freshman spring semester. STEM women higher in gender rejection sensitivity, or gender RS, a social-cognitive measure assessing the tendency to perceive social-identity threat, experienced larger fluctuations in gender-STEM compatibility across their second semester of college. Fluctuations in compatibility predicted impaired outcomes the following school year, including lower STEM engagement and lower academic performance in STEM (but not non-STEM) classes, and significantly mediated the relationship between gender RS and STEM engagement and achievement in the 2nd year of college. The week-to-week changes in gender-STEM compatibility occurred in response to negative academic (but not social) experiences.

  19. The use of the bicycle compatibility index in identifying gaps and deficiencies in bicycle networks

    NASA Astrophysics Data System (ADS)

    Ilie, A.; Oprea, C.; Costescu, D.; Roşca, E.; Dinu, O.; Ghionea, F.

    2016-11-01

    Currently, no methodology is widely accepted by engineers, planners, or bicycle coordinators that allow them to determine how compatible a roadway is in providing efficient operation of both bicycles and motor vehicles. Previous studies reported a number of approaches to obtain an appropriate level of service; some authors developed the bicycle level of service (BLOS) and other authors developed the bicycle compatibility indexes (BCI). The level of service (BLOS) for a bicycle route represents an evaluation of safety and commodity perceived by a bicyclist reported to the motorized traffic, while running on the road surface. The bicycle compatibility index (BCI) is used by bicycle coordinators, transportation planners, traffic engineers to evaluate the capability of specific roadways to accommodate both motorists and bicyclists and to plan for and design roadways that are bicycle compatible. After applying BCI and BLOS models for the designed bicycle infrastructure network in the city of Dej, one can see that only few streets are Moderately Low compatible compared to the others with a high degree of compatibility that recommends to include them in the bicycle infrastructure network.

  20. Servicer system demonstration plan and capability development

    NASA Technical Reports Server (NTRS)

    1987-01-01

    An orbital maneuvering vehicle (OMV) front end kit is defined which is capable of performing in-situ fluid resupply and modular maintenance of free flying spacecraft based on the integrated orbital servicing system (IOSS) concept. The compatibility of the IOSS to perform gas and fluid umbilical connect and disconnect functions utilizing connect systems currently available or in development is addressed. A series of tasks involving on-orbit servicing and the engineering test unit (ETU) of the on-orbit service were studied. The objective is the advancement of orbital servicing by expanding the Spacecraft Servicing Demonstration Plan (SSDP) to include detail demonstration planning using the Multimission Modular Spacecraft (MMS) and upgrading the ETU control.

  1. Engineering development and demonstration of DETOX{sup SM} wet oxidation for mixed waste treatment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dhooge, P.M.; Goldblatt, S.D.; Moslander, J.E.

    1997-12-01

    DETOX{sup SM}, a catalyzed chemical oxidation process, is under development for treatment of hazardous and mixed wastes at Department of Energy sites. To support this effort, developmental engineering studies have been formed for aspects of the process to help ensure safe and effective operation. Subscale agitation studies have been preformed to identify a suitable mixing head and speed for the primary reaction vessel agitator. Mechanisms for feeding solid waste materials to the primary reaction vessel have been investigated. Filtration to remove solid field process residue, and the use of various filtration aids, has been studied. Extended compatibility studies on themore » materials of construction have been performed. Due to a change to Rocky Flats Environmental Technology Site (RFETS) for the mixed waste portion of the demonstration, types of wastes suitable and appropriate for treatment at RFETS had to be chosen. A Prototype unit has been fabricated and will be demonstrated on hazardous and mixed wastes at Savannah River Site (SRS) and RFETS during 1997 and 1998. The unit is in shakedown testing at present. Data validation and an engineering evaluation will be performed during the demonstration.« less

  2. Facial and semantic emotional interference: A pilot study on the behavioral and cortical responses to the dual valence association task

    PubMed Central

    2011-01-01

    Background Integration of compatible or incompatible emotional valence and semantic information is an essential aspect of complex social interactions. A modified version of the Implicit Association Test (IAT) called Dual Valence Association Task (DVAT) was designed in order to measure conflict resolution processing from compatibility/incompatibly of semantic and facial valence. The DVAT involves two emotional valence evaluative tasks which elicits two forms of emotional compatible/incompatible associations (facial and semantic). Methods Behavioural measures and Event Related Potentials were recorded while participants performed the DVAT. Results Behavioural data showed a robust effect that distinguished compatible/incompatible tasks. The effects of valence and contextual association (between facial and semantic stimuli) showed early discrimination in N170 of faces. The LPP component was modulated by the compatibility of the DVAT. Conclusions Results suggest that DVAT is a robust paradigm for studying the emotional interference effect in the processing of simultaneous information from semantic and facial stimuli. PMID:21489277

  3. Study of the cerrado vegetation in the Federal District area from orbital data. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Dejesusparada, N. (Principal Investigator); Aoki, H.; Dossantos, J. R.

    1980-01-01

    The physiognomic units of cerrado in the area of Distrito Federal (DF) were studied through the visual and automatic analysis of products provided by Multispectral Scanning System (MSS) of LANDSAT. The visual analysis of the multispectral images in black and white, at the 1:250,000 scale, was made based on the texture and tonal patterns. The automatic analysis of the compatible computer tapes (CCT) was made by means of IMAGE-100 system. The following conclusions were obtained: (1) the delimitation of cerrado vegetation forms can be made by the visual and automatic analysis; (2) in the visual analysis, the principal parameter used to discriminate the cerrado forms was the tonal pattern, independently of the year's seasons, and the channel 5 gave better information; (3) in the automatic analysis, the data of the four channels of MSS can be used in the discrimination of the cerrado forms; and (4) in the automatic analysis, the four channels combination possibilities gave more information in the separation of cerrado units when soil types were considered.

  4. Integration of red cell genotyping into the blood supply chain: a population-based study.

    PubMed

    Flegel, Willy A; Gottschall, Jerome L; Denomme, Gregory A

    2015-07-01

    When problems with compatibility arise, transfusion services often use time-consuming serological tests to identify antigen-negative red cell units for safe transfusion. New methods have made red cell genotyping possible for all clinically relevant blood group antigens. We did mass-scale genotyping of donor blood and provided hospitals with access to a large red cell database to meet the demand for antigen-negative red cell units beyond ABO and Rh blood typing. We established a red cell genotype database at the BloodCenter of Wisconsin on July 17, 2010. All self-declared African American, Asian, Hispanic, and Native American blood donors were eligible irrespective of their ABO and Rh type or history of donation. Additionally, blood donors who were groups O, A, and B, irrespective of their Rh phenotype, were eligible for inclusion only if they had a history of at least three donations in the previous 3 years, with one donation in the previous 12 months at the BloodCenter of Wisconsin. We did red cell genotyping with a nanofluidic microarray system, using 32 single nucleotide polymorphisms to predict 42 blood group antigens. An additional 14 antigens were identified via serological phenotype. We monitored the ability of the red cell genotype database to meet demand for compatible blood during 3 years. In addition to the central database at the BloodCenter of Wisconsin, we gave seven hospitals online access to a web-based antigen query portal on May 1, 2013, to help them to locate antigen-negative red cell units in their own inventories. We analysed genotype data for 43,066 blood donors. Requests were filled for 5661 (99.8%) of 5672 patient encounters in which antigen-negative red cell units were needed. Red cell genotyping met the demand for antigen-negative blood in 5339 (94.1%) of 5672 patient encounters, and the remaining 333 (5.9%) requests were filled by use of serological data. Using the 42 antigens represented in our red cell genotype database, we were able to fill 14,357 (94.8%) of 15,140 requests for antigen-negative red cell units from hospitals served by the BloodCenter of Wisconsin. In the pilot phase, the seven hospitals identified 71 units from 52 antigen-negative red cell unit requests. Red cell genotyping has the potential to transform the way antigen-negative red cell units are provided. An antigen query portal could reduce the need for transportation of blood and serological screening. If this wealth of genotype data can be made easily accessible online, it will help with the supply of affordable antigen-negative red cell units to ensure patient safety. BloodCenter of Wisconsin Diagnostic Laboratories Strategic Initiative and the NIH Clinical Center Intramural Research Program. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. X-ray optical units made of glass: achievements and perspectives

    NASA Astrophysics Data System (ADS)

    Civitani, M.; Basso, S.; Ghigo, M.; Pareschi, G.; Salmaso, B.; Spiga, D.; Tagliaferri, G.; Vecchi, G.; Burwitz, V.; Hartner, G. D.; Menz, B.

    2014-07-01

    Future X-ray telescopes with very large collecting area, like the proposed Athena with more than 2 m2 effective area at 1 keV, need to be realized as assemblies of a large number of X-ray optical units, named X-ray Optical Units (XOUs). The Brera Astronomical Observatory (INAF-OAB) is developing a new technology to manufacture these modular elements, compatible with an angular resolution of 5 arcsec HEW (Half-Energy-Width). This technique consists in stacking in a Wolter-I configuration several layers of thin foils of glass, previously formed by direct hot slumping. The achievable global angular resolution of the optics relies on the required surface shape accuracy of slumped foils, on the smoothness of the mirror surfaces and on the correct integration and co-alignment of the mirror segments operated trough a dedicated Integration Machine (IMA). In this paper we provide an overview of the project development, reporting on the very promising results achieved so far, including in-focus full illumination X-ray tests of the prototype (Proof of Concept, POC#2, integrated at the beginning of 2013) for which an HEW of 22.1'' has been measured at Panter/MPE. Moreover we report on the on-going activities, with a new integrated prototype (PoC#3). X-ray test in pencil beam revealed that at least a segment between two external ribs is characterized by an HEW well below 10''. Lastly, the overall process up-grade to go from 20 m to 12m focal length (to be compatible with Athena+ configuration) is presented.

  6. Holographic Patterning of High Performance on-chip 3D Lithium-ion Microbatteries

    DOE PAGES

    Ning, Hailong; Pikul, James H.; Wang, Runyu; ...

    2015-05-11

    As sensors, wireless communication devices, personal health monitoring systems, and autonomous microelectromechanical systems (MEMS) become distributed and smaller, there is an increasing demand for miniaturized integrated power sources. Although thin-film batteries are well-suited for on-chip integration, their energy and power per unit area are limited. Three-dimensional electrode designs have potential to offer much greater power and energy per unit area; however, efforts to date to realize 3D microbatteries have led to prototypes with solid electrodes (and therefore low power) or mesostructured electrodes not compatible with manufacturing or on-chip integration. Here in this paper, we demonstrate an on-chip compatible method tomore » fabricate high energy density (6.5 μWh cm -2∙μm -1) 3D mesostructured Li-ion microbatteries based on LiMnO 2 cathodes, and NiSn anodes that possess supercapacitor-like power (3,600 μW cm(-2)∙μm(-1) peak). The mesostructured electrodes are fabricated by combining 3D holographic lithography with conventional photolithography, enabling deterministic control of both the internal electrode mesostructure and the spatial distribution of the electrodes on the substrate. The resultant full cells exhibit impressive performances, for example a conventional light-emitting diode (LED) is driven with a 500-μA peak current (600-C discharge) from a 10-μm-thick microbattery with an area of 4 mm 2 for 200 cycles with only 12% capacity fade. Lastly, a combined experimental and modeling study where the structural parameters of the battery are modulated illustrates the unique design flexibility enabled by 3D holographic lithography and provides guidance for optimization for a given application.« less

  7. Holographic patterning of high-performance on-chip 3D lithium-ion microbatteries

    PubMed Central

    Ning, Hailong; Pikul, James H.; Zhang, Runyu; Li, Xuejiao; Xu, Sheng; Wang, Junjie; Rogers, John A.; King, William P.; Braun, Paul V.

    2015-01-01

    As sensors, wireless communication devices, personal health monitoring systems, and autonomous microelectromechanical systems (MEMS) become distributed and smaller, there is an increasing demand for miniaturized integrated power sources. Although thin-film batteries are well-suited for on-chip integration, their energy and power per unit area are limited. Three-dimensional electrode designs have potential to offer much greater power and energy per unit area; however, efforts to date to realize 3D microbatteries have led to prototypes with solid electrodes (and therefore low power) or mesostructured electrodes not compatible with manufacturing or on-chip integration. Here, we demonstrate an on-chip compatible method to fabricate high energy density (6.5 μWh cm−2⋅μm−1) 3D mesostructured Li-ion microbatteries based on LiMnO2 cathodes, and NiSn anodes that possess supercapacitor-like power (3,600 μW cm−2⋅μm−1 peak). The mesostructured electrodes are fabricated by combining 3D holographic lithography with conventional photolithography, enabling deterministic control of both the internal electrode mesostructure and the spatial distribution of the electrodes on the substrate. The resultant full cells exhibit impressive performances, for example a conventional light-emitting diode (LED) is driven with a 500-μA peak current (600-C discharge) from a 10-μm-thick microbattery with an area of 4 mm2 for 200 cycles with only 12% capacity fade. A combined experimental and modeling study where the structural parameters of the battery are modulated illustrates the unique design flexibility enabled by 3D holographic lithography and provides guidance for optimization for a given application. PMID:25964360

  8. Non-targeted evaluation of selectivity of water-compatible class selective adsorbents for the analysis of steroids in wastewater.

    PubMed

    Kopperi, Matias; Riekkola, Marja-Liisa

    2016-05-12

    Selective adsorbents for solid-phase extraction are needed to meet the low concentration requirements of new environmental quality standard directives, especially for the analysis of estrogens in wastewater. In this work, bulk polymerization procedures were first optimized for the synthesis of non-imprinted polymers (NIP) with low non-specific adsorption of nonpolar compounds in aqueous environments. Water-compatible molecularly imprinted polymers (MIP) were then synthetized by increasing the selectivity of the polymer towards steroids with a testosterone template (average imprinting factor > 10). In addition, the affinity of synthetized entrapped β-cyclodextrin-epichlorohydrin polymers (ECD) towards steroids was clarified. The polymers were applied to the extraction of spiked wastewater effluent samples and their performance compared to commercially available adsorbents. The selectivity of the studied adsorbents was evaluated utilizing liquid chromatography ‒ mass spectrometry as well as comprehensive two-dimensional gas chromatography ‒ time-of-flight mass spectrometry. Affinity between adsorbents and steroids as well as matrix removal potential were measured with targeted methodologies, and two novel non-targeted methodologies were proposed to quantitatively measure adsorbent selectivity by utilizing chemometrics. Semi-quantitative selectivity was measured from the ratio of peak areas between steroidal and other compounds. Semi-qualitative selectivity was calculated from the ratio between the number of tentatively identified steroidal and other compounds. The synthetized polymers provided good matrix removal potential (ion suppression 15-30%) and semi-qualitative selectivity (∼4 units) compared to the commercial adsorbents (ion suppression 45-80%, selectivity < 3 units). Simple non-targeted approaches provided a novel method of quantifying the selectivity of extraction. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Critical features of an auditable management system for an ISO 9000-compatible occupational health and safety standard.

    PubMed

    Levine, S; Dyjack, D T

    1997-04-01

    An International Organization for Standardization (ISO) 9001: 1994-harmonized occupational health and safety (OHS) management system has been written at the University of Michigan, and reviewed, revised, and accepted under the direction of the American Industrial Hygiene Association (AIHA) Occupational Health and Safety Management Systems (OHSMS) Task Force and the Board of Directors. This system is easily adaptable to the ISO 14001 format and to both OHS and environmental management system applications. As was the case with ISO 9001: 1994, this system is expected to be compatible with current production quality and OHS quality systems and standards, have forward compatibility for new applications, and forward flexibility, with new features added as needed. Since ISO 9001: 1987 and 9001: 1994 have been applied worldwide, the incorporation of harmonized OHS and environmental management system components should be acceptable to business units already performing first-party (self-) auditing, and second-party (contract qualification) auditing. This article explains the basis of this OHS management system, its relationship to ISO 9001 and 14001 standards, the philosophy and methodology of an ISO-harmonized system audit, the relationship of these systems to traditional OHS audit systems, and the authors' vision of the future for application of such systems.

  10. High Input Voltage, Silicon Carbide Power Processing Unit Performance Demonstration

    NASA Technical Reports Server (NTRS)

    Bozak, Karin E.; Pinero, Luis R.; Scheidegger, Robert J.; Aulisio, Michael V.; Gonzalez, Marcelo C.; Birchenough, Arthur G.

    2015-01-01

    A silicon carbide brassboard power processing unit has been developed by the NASA Glenn Research Center in Cleveland, Ohio. The power processing unit operates from two sources: a nominal 300 Volt high voltage input bus and a nominal 28 Volt low voltage input bus. The design of the power processing unit includes four low voltage, low power auxiliary supplies, and two parallel 7.5 kilowatt (kW) discharge power supplies that are capable of providing up to 15 kilowatts of total power at 300 to 500 Volts (V) to the thruster. Additionally, the unit contains a housekeeping supply, high voltage input filter, low voltage input filter, and master control board, such that the complete brassboard unit is capable of operating a 12.5 kilowatt Hall effect thruster. The performance of the unit was characterized under both ambient and thermal vacuum test conditions, and the results demonstrate exceptional performance with full power efficiencies exceeding 97%. The unit was also tested with a 12.5kW Hall effect thruster to verify compatibility and output filter specifications. With space-qualified silicon carbide or similar high voltage, high efficiency power devices, this would provide a design solution to address the need for high power electric propulsion systems.

  11. Origami Metamaterial based on Pattern Rigidity

    NASA Astrophysics Data System (ADS)

    Chen, Yan; You, Zhong

    Origami inspired mechanical metamaterials are made from a tessellation of origami units. Their mechanical behaviour is closely related to the behaviour of the origami units used. In this article, we focus on a family of metamaterials that are created by the tessellation of the square twist origami units. Generally a square twist origami unit can have four distinct hill-valley crease arrangements, two of which are rigidly foldable whereas the others are not. The rigidly foldable unit has, in general, lower stiffness than that of the non-rigidly foldable one if the facets can easily rotate about the creases. We shall show that it is possible to put rigidly foldable and non-rigidly foldable units together to form a geometrically compatible tessellation, and the stiffness of the overall structure based on such a tessellation is primarily decided by the number of non-rigid units. By astutely placing such units in a tessellation, we are able to create a metamaterial with a tunable stiffness. Y Chen acknowledges the support of the NSFC (Projects 51290293 and 51422506) and the Ministry of Science and Technology of China (Project 2014DFA70710). Z You wishes to acknowledge the support of Air Force Office of Scientific Research (FA9550-16-1-0339).

  12. Nanodiamonds as platforms for biology and medicine.

    PubMed

    Man, Han B; Ho, Dean

    2013-02-01

    Nanoparticles possess a wide range of exceptional properties applicable to biology and medicine. In particular, nanodiamonds (NDs) are being studied extensively because they possess unique characteristics that make them suitable as platforms for diagnostics and therapeutics. This carbon-based material (2-8 nm) is medically relevant because it unites several key properties necessary for clinical applications, such as stability and compatibility in biological environments, and scalability in production. Research by the Ho group and others has yielded ND particles with a variety of capabilities ranging from delivery of chemotherapeutic drugs to targeted labeling and uptake studies. In addition, encouraging new findings have demonstrated the ability for NDs to effectively treat chemoresistant tumors in vivo. In this review, we highlight the progress made toward bringing nanodiamonds from the bench to the bedside.

  13. NEXT Ion Thruster Performance Dispersion Analyses

    NASA Technical Reports Server (NTRS)

    Soulas, George C.; Patterson, Michael J.

    2008-01-01

    The NEXT ion thruster is a low specific mass, high performance thruster with a nominal throttling range of 0.5 to 7 kW. Numerous engineering model and one prototype model thrusters have been manufactured and tested. Of significant importance to propulsion system performance is thruster-to-thruster performance dispersions. This type of information can provide a bandwidth of expected performance variations both on a thruster and a component level. Knowledge of these dispersions can be used to more conservatively predict thruster service life capability and thruster performance for mission planning, facilitate future thruster performance comparisons, and verify power processor capabilities are compatible with the thruster design. This study compiles the test results of five engineering model thrusters and one flight-like thruster to determine unit-to-unit dispersions in thruster performance. Component level performance dispersion analyses will include discharge chamber voltages, currents, and losses; accelerator currents, electron backstreaming limits, and perveance limits; and neutralizer keeper and coupling voltages and the spot-to-plume mode transition flow rates. Thruster level performance dispersion analyses will include thrust efficiency.

  14. Effects of in-vehicle warning information displays with or without spatial compatibility on driving behaviors and response performance.

    PubMed

    Liu, Yung-Ching; Jhuang, Jing-Wun

    2012-07-01

    A driving simulator study was conducted to evaluate the effects of five in-vehicle warning information displays upon drivers' emergent response and decision performance. These displays include visual display, auditory displays with and without spatial compatibility, hybrid displays in both visual and auditory format with and without spatial compatibility. Thirty volunteer drivers were recruited to perform various tasks that involved driving, stimulus-response, divided attention and stress rating. Results show that for displays of single-modality, drivers benefited more when coping with visual display of warning information than auditory display with or without spatial compatibility. However, auditory display with spatial compatibility significantly improved drivers' performance in reacting to the divided attention task and making accurate S-R task decision. Drivers' best performance results were obtained for hybrid display with spatial compatibility. Hybrid displays enabled drivers to respond the fastest and achieve the best accuracy in both S-R and divided attention tasks. Copyright © 2011 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  15. Electrical Power Subsystem Integration and Test for the NPS Solar Cell Array Tester CubeSat

    DTIC Science & Technology

    2010-12-01

    Earth’s Gravitational Constant MCU Microcontroller Unit MPPT Maximum Power Point Tracker NiCr Nickel Chromium NPS Naval Postgraduate School P...new testing platform was designed, built, and used to conduct integrated testing on CubeSat Kit (CSK) compatible devices. The power budgets and...acceptance test results obtained from the testing platform were used with a solar array power generation simulation, and a battery state of charge

  16. Anti-m antibody in solid tumors-two case reports.

    PubMed

    Soni, Shiv Kumar; Goyal, Hari; Sood, S K; Setia, Rasika

    2014-09-01

    Anti-M antibodies are usually of IgM, appear as cold agglutinins and are clinically insignificant. We are reporting two cases of anti-M in cases of solid tumors where the anti-M caused discrepancy in blood grouping, reacted in coombs phase of crossmatching. Anti-M in first case showed dosage effect. These antibodies can be clinical significant when detected in coombs phase, making M antigen negative coombs compatible unit transfusion imperative.

  17. Polymeric Ionic Networks with High Charge Density: Solid-like Electrolytes in Lithium Metal Batteries

    DOE PAGES

    Zhang, Pengfei; Li, Mingtao; Jiang, Xueguang; ...

    2015-11-02

    Polymerized ionic networks (PINs) with six ion pairs per repeating unit are synthesized by nucleophilic-substitution-mediated polymerization or radical polymerization of monomers bearing six 1-vinylimidazolium cations. PIN-based solid-like electrolytes show good ionic conductivities (up to 5.32 × 10 -3 S cm -1 at 22 °C), wide electrochemical stability windows (up to 5.6 V), and good interfacial compatibility with the electrodes.

  18. Spectrum Management and Electromagnetic Compatibility Issues in the Department of Defense

    DTIC Science & Technology

    1991-01-01

    Interference JEWC Joint Electronic Warfare Center JRFL Joint Restricted Frequency List JSMS Joint Spectrum Management System JT&E Joint Test and Evaluation JTAC...Joint Restricted Frequency List (JRFL) is essentially a list of frequencies prohibited from use by ECM units. Creation and maintenance of the JRFL to...sponsored by CECOM, developed a prototype that primarily acted as an analysis of the restricted frequency list as a predecessor to DECON. Presently the Army

  19. Compatibility of epirubicin-loaded DC bead™ with different non-ionic contrast media.

    PubMed

    Sarakbi, Iman; Krämer, Irene

    2016-12-01

    The aim of this study was to determine the compatibility of epirubicin-loaded DC bead™ with different non-ionic contrast media over a period of seven days when stored light protected under refrigerated conditions. DC bead™ (2 ml) (Biocompatibles UK Ltd) of the bead size 70-150 µm ( = DC bead M1) or bead size 100-300 µm were loaded with 75 mg epirubicin powder formulation (Farmorubicin® dissolved in 3 ml water for injection to a concentration of 25 mg/ml) or 76 mg epirubicin injection solution (Epimedac® 2 mg/ml) within 2 h or 6 h, respectively. After removal of the excess solution, the epirubicin-loaded beads were mixed in polypropylene syringes with an equal volume (∼1.5 ml) of contrast media, i.e. Accupaque™ 300 (Nycomed Inc.), Imeron® 300 (Bracco S.p.A), Ultravist® 300 (Bayer Pharma AG), Visipaque™ 320 (GE Healthcare) and agitated in a controlled manner to get a homogenous suspension. Syringes with loaded beads in contrast media were stored protected from light under refrigeration (2-8℃). Compatibility was determined by measuring epirubicin concentrations in the suspensions in triplicate on day 0, 1, and 7. A reversed phase high-performance liquid chromatography assay with ultraviolet detection was utilized to analyze the concentration and purity of epirubicin. Mixing of epirubicin-loaded beads with different non-ionic contrast media released 0.1-0.5% of epirubicin over a period of 24 h, irrespectively, of the DC bead™ size or type of contrast media. No further elution or degradation was observed after seven days when the admixtures were stored protected from light under refrigeration. Compatibility of epirubicin-loaded DC bead™ with an equal volume of different contrast media in polypropylene syringes is given over a period of seven days. Due to a maximum elution of 0.1-0.5% of epirubicin from loaded DC bead™, admixtures with contrast media can be prepared in advance in centralized cytotoxic preparation units. Microbiological aspects have to be considered when determining the expiration date of the product. © The Author(s) 2015.

  20. Nanoelectronics enabled chronic multimodal neural platform in a mouse ischemic model.

    PubMed

    Luan, Lan; Sullender, Colin T; Li, Xue; Zhao, Zhengtuo; Zhu, Hanlin; Wei, Xiaoling; Xie, Chong; Dunn, Andrew K

    2018-02-01

    Despite significant advancements of optical imaging techniques for mapping hemodynamics in small animal models, it remains challenging to combine imaging with spatially resolved electrical recording of individual neurons especially for longitudinal studies. This is largely due to the strong invasiveness to the living brain from the penetrating electrodes and their limited compatibility with longitudinal imaging. We implant arrays of ultraflexible nanoelectronic threads (NETs) in mice for neural recording both at the brain surface and intracortically, which maintain great tissue compatibility chronically. By mounting a cranial window atop of the NET arrays that allows for chronic optical access, we establish a multimodal platform that combines spatially resolved electrical recording of neural activity and laser speckle contrast imaging (LSCI) of cerebral blood flow (CBF) for longitudinal studies. We induce peri-infarct depolarizations (PIDs) by targeted photothrombosis, and show the ability to detect its occurrence and propagation through spatiotemporal variations in both extracellular potentials and CBF. We also demonstrate chronic tracking of single-unit neural activity and CBF over days after photothrombosis, from which we observe reperfusion and increased firing rates. This multimodal platform enables simultaneous mapping of neural activity and hemodynamic parameters at the microscale for quantitative, longitudinal comparisons with minimal perturbation to the baseline neurophysiology. The ability to spatiotemporally resolve and chronically track CBF and neural electrical activity in the same living brain region has broad applications for studying the interplay between neural and hemodynamic responses in health and in cerebrovascular and neurological pathologies. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. [Compatibility of Work and Family Life of Employees in the Healthcare Sector: An Issue in Health Services Research].

    PubMed

    Lukasczik, Matthias; Ahnert, Jutta; Ströbl, Veronika; Vogel, Heiner; Donath, Carolin; Enger, Ilka; Gräßel, Elmar; Heyelmann, Lena; Lux, Heidemarie; Maurer, Jochen; Özbe, Dominik; Spieckenbaum, Stefanie; Voigtländer, Elzbieta; Wildner, Manfred; Zapf, Andreas; Zellner, Angela; Hollederer, Alfons

    2017-05-18

    Background Healthcare professionals are confronted with specific work-related demands that influence work-family relations and might indirectly affect the quality of healthcare. This paper seeks to provide an overview of the current state of research on this topic of relevance to health services research. The overview may serve as a starting point for modifying structures in the healthcare system (especially in rural regions) with the aim of improving work-family compatibility. Methods A systematic national and international literature search was conducted in terms of a scoping review. The following criteria/contents to be covered in publications were defined: work-family compatibility; work-family interface and work-family conflict in employees working in healthcare; healthcare professions in rural areas and links with work-family issues; interventions to improve work-family compatibility. 145 publications were included in the overview. Results The available literature focuses on physicians and nursing staff while publications on other professions are largely lacking. The methodological quality of existing studies is mostly low, including a lack of meta-analyses. Several studies document dissatisfaction in physicians and nursing staff regarding reconciliation of work and family life. Only few intervention studies were found that seek to improve work-life compatibility; few of them focus on employees in healthcare. There are also deficits with respect to linking work-family issues with aspects of healthcare in rural areas. Conclusions There is a shortage of systematic national and international research regarding work-family compatibility, especially when it comes to the evaluation of interventions. The overview provides starting points for improving work-family compatibility in healthcare. © Georg Thieme Verlag KG Stuttgart · New York.

  2. Review on Prescription Compatibility of Shaoyao Gancao Decoction and Reflection on Pharmacokinetic Compatibility Mechanism of Traditional Chinese Medicine Prescription Based on In Vivo Drug Interaction of Main Efficacious Components

    PubMed Central

    Bi, Xiaolin; Gong, Meirong; Di, Liuqing

    2014-01-01

    Shaoyao Gancao Decoction (SGD) derived from Zhang Zhongjing's “Typhoid Theory” is composed of peony and licorice, having the efficacy of nourishing liver, relaxing spasm, and relieving pain. Modern compatibility studies of SGD on chemistry, pharmacology, and pharmacokinetics all demonstrate the reasonable compatibility of peony and licorice. However, the present research on pharmacokinetics is only descriptive and limited to the influence on in vivo dynamic process of certain ingredients; correspondingly, there is lack of studies on the essence of these efficacious substances' in vivo changes; that is, whether it is because there exists in vivo drug interaction in absorption, distribution, metabolism, and excretion (ADME) of active ingredients that leads to the improvement of bioavailability. We herein take SGD as an example and suggest that it is necessary to study in vivo drug interaction of main efficacious components mediated by metabolic enzymes, transport proteins, or plasma protein binding in the course of ADME, which is helpful to illustrate the principle of pharmacokinetic compatibility from the essence leading to the changes of effective substances in vivo. PMID:25147573

  3. Impact of ABO-Identical vs ABO-Compatible Nonidentical Plasma Transfusion in Trauma Patients

    DTIC Science & Technology

    2010-09-01

    and B patients in turn could receive AB donor plasma. Few studies have examined the im- pact of compatible nonidentical plasma transfusion . In platelet ... transfusion ,19 the administration of compatible nonidenti- cal platelets to patients undergoing coro- nary artery bypass grafting or valve re...significantly different (in boldface) and for the volume of packed red blood cells, plasma, platelets , cryoprecipitate, and factor VIIa transfused . cBecause

  4. High-temperature compatibility study of iridium (DOP-26 alloy) with graphite and plutonia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Axler, K.M.; Eash, D.T.

    1987-12-01

    This report outlines the materials compatibility tests conducted on DOP-26 iridium alloy and carbon. The carbon used was in the form of woven graphite as present in the impact shell used to encase plutonia in nuclear heat sources. In addition, compatibility tests of the DOP-26 alloy with plutonia are described. The reactivity observed in both systems is discussed. 4 refs., 6 figs.

  5. Music and the brain - design of an MEG compatible piano.

    PubMed

    Chacon-Castano, Julian; Rathbone, Daniel R; Hoffman, Rachel; Heng Yang; Pantazis, Dimitrios; Yang, Jason; Hornberger, Erik; Hanumara, Nevan C

    2017-07-01

    Magnetoencephalography (MEG) neuroimaging has been used to study subjects' responses when listening to music, but research into the effects of playing music has been limited by the lack of MEG compatible instruments that can operate in a magnetically shielded environment without creating electromagnetic interference. This paper describes the design and preliminary testing of an MEG compatible piano keyboard with 25 full size keys that employs a novel 3-state optical encoder design and electronics to provide realistic velocity-controlled volume modulation. This instrument will allow researchers to study musical performance on a finer timescale than fMRI and enable a range of MEG studies.

  6. Thermodynamic Analysis of Compatibility of Several Reinforcement Materials with Beta Phase NiAl Alloys

    NASA Technical Reports Server (NTRS)

    Misra, Ajay K.

    1988-01-01

    Chemical compatibility of several reinforcement materials with beta phase NiAl alloys within the concentration range 40 to 50 at. percent Al have been analyzed from thermodynamic considerations at 1373 and 1573 K. The reinforcement materials considered in this study include carbides, borides, oxides, nitrides, beryllides, and silicides. Thermodynamic data for NiAl alloys have been reviewed and activity of Ni and Al in the beta phase have been derived at 1373 and 1573 K. Criteria for chemical compatibility between the reinforcement material and the matrix have been defined and several chemically compatible reinforcement materials have been defined.

  7. Flow Cytometric Panel-Reactive Antibody Results and the Ability to Find Transfusion-Compatible Platelets after Antibody-Desensitization for Allogeneic Bone Marrow Transplant.

    PubMed

    Rosenbaum, Eric R; Pandey, Soumya; Harville, Terry O; Drobena, Gina A; Cottler-Fox, Michele

    2016-12-01

    Panel reactive antibody (PRA) reduction protocols are used to decrease anti-HLA antibodies with concomitant PRA monitoring as a measure of successful treatment prior to organ and haploidentical blood and marrow transplant (BMT). We hypothesized that the more sensitive flow cytometry (FC) based assays for PRA [FlowPRA ® and Luminex ® based Single Antigen Bead (SAB)] would also correlate with the ability to find compatible platelets for allosensitized recipients. A female patient with myelodysplastic syndrome and a high HLA class I PRA [>90% PRA and cPRA by complement-dependent cytotoxicity (CDC) assay and Flow PRA] required allogeneic BMT. Baseline HLA Class I and class II antigen typing was performed and a matched sibling donor was identified. Although baseline anti-HLA class I and class II antibodies measured by FC and CDC revealed no donor specific antibodies (DSA), the decision was made to attempt antibody desensitization to facilitate platelet transfusion during BMT. FC and CDC assays were performed to determine anti-HLA class I antibodies and cPRA/%PRA prior to starting desensitization and at the end of desensitization. Over the course of desensitization and BMT, a total of 194 apheresis platelet units underwent cross-match (XM) using Capture-P ® . We compared temporally-related PRA results with platelet XM results. High PRA by FC or CDC assays correlates with a high % of XM-positive (incompatible) platelet units. When the CDC PRA fell to 2% after desensitization, platelet XM incompatibility fell from 100% to 63% positive (incompatible). When the FC PRA fell to 5% the positive platelet XM fell to 5%. Antibody desensitization facilitated platelet transfusion. PRA determination by FC appeared better correlated than determination by CDC with the ability to find XM-compatible platelets. © 2016 by the Association of Clinical Scientists, Inc.

  8. Invasive candidiasis and oral manifestations in premature newborns.

    PubMed

    Tinoco-Araujo, José Endrigo; Araújo, Diana Ferreira Gadelha; Barbosa, Patrícia Gomes; Santos, Paulo Sérgio da Silva; Medeiros, Ana Myriam Costa de

    2013-01-01

    To investigate prevalence of invasive candidiasis in a Neonatal Intensive Care Unit and to evaluate oral diseases and Candida spp. colonization in low birth weight preterm newborns. A descriptive epidemiological study performed in two stages. First, prevalence of candidiasis was analyzed in a database of 295 preterm patients admitted to hospital for over 10 days and birth weight less than 2,000g. In the second stage, oral changes and Candida spp. colonization were assessed in 65 patients weighing less than 2,000g, up to 4 week-old, hospitalized for over 10 days and presenting oral abnormalities compatible with fungal lesions. Swab samples were collected in the mouth to identify fungi. Prevalence of candidiasis was 5.4% in the database analyzed. It correlated with prolonged hospital length of stay (p<0.001), in average, 31 days, and 85% risk of developing infection in the first 25 days. It correlated with low birth weight (p<0.001), with mean of 1,140g. The most frequent alterations were white soft plaques, detachable, in oral mucosa and tongue. Intense oral colonization by Candida spp was observed (80%). The frequency of invasive candidiasis was low and correlated with low birth weight and prolonged hospital stay. The most common oral changes were white plaques compatible with pseudomembranous candidiasis and colonization by Candida spp. was above average.

  9. Motivation for career choice and job satisfaction of GP trainees and newly qualified GPs across Europe: a seven countries cross-sectional survey.

    PubMed

    Roos, Marco; Watson, Jessica; Wensing, Michel; Peters-Klimm, Frank

    2014-07-01

    Recruitment to general practice is a major concern in many countries. Cross-national exploration of motivation for career choice and career satisfaction could help inform workforce planning. Our aim was to explore motivation for career choice and job satisfaction of GP trainees and newly qualified GPs (NQGP) across seven European countries. We surveyed GP trainees and recently qualified GPs in the Czech Republic, Denmark, Germany, Italy, Norway, Portugal and the United Kingdom using a web-based questionnaire. The number of individuals who responded was 3722 (2533 GP trainees; 1189 NQGP). The most frequently cited reasons for choosing GP were 'compatibility with family life' (59.5%), 'challenging medically broad discipline' (58.9%), 'individual approach to people' (40.1%), 'holistic approach' (37.8%) and 'autonomy and independence' (30.4%). Despite differences in workload, work-life balance and earnings, overall job satisfaction was high, with over 80% saying that they would choose to be a doctor again; of these 78.4% would choose to be a GP again. In our sample reasons for choosing general practice as a career were strongly positive, with compatibility with family life the most frequently cited reason overall. This has implications for workforce planning. Further qualitative studies are needed to explore issues raised in more detail.

  10. Evaluation of the functional performance and technical quality of an Electronic Documentation System of the Nursing Process.

    PubMed

    de Oliveira, Neurilene Batista; Peres, Heloisa Helena Ciqueto

    2015-01-01

    To evaluate the functional performance and the technical quality of the Electronic Documentation System of the Nursing Process of the Teaching Hospital of the University of São Paulo. exploratory-descriptive study. The Quality Model of regulatory standard 25010 and the Evaluation Process defined under regulatory standard 25040, both of the International Organization for Standardization/International Electrotechnical Commission. The quality characteristics evaluated were: functional suitability, reliability, usability, performance efficiency, compatibility, security, maintainability and portability. The sample was made up of 37 evaluators. in the evaluation of the specialists in information technology, only the characteristic of usability obtained a rate of positive responses of less than 70%. For the nurse lecturers, all the quality characteristics obtained a rate of positive responses of over 70%. The staff nurses of the medical and surgical clinics with experience in using the system) and staff nurses from other units of the hospital and from other health institutions (without experience in using the system) obtained rates of positive responses of more than 70% referent to the functional suitability, usability, and security. However, performance efficiency, reliability and compatibility all obtained rates below the parameter established. the software achieved rates of positive responses of over 70% for the majority of the quality characteristics evaluated.

  11. Studies of Carbon Nanotubes

    NASA Technical Reports Server (NTRS)

    Caneba, Gerard T.

    2005-01-01

    The fellowship experience for this summer for 2004 pertains to carbon nanotube coatings for various space-related applications. They involve the following projects: (a) EMI protection films from HiPco-polymers, and (b) Thermal protection nanosilica materials. EMI protection films are targeted to be eventually applied onto casings of laptop computers. These coatings are composites of electrically-conductive SWNTs and compatible polymers. The substrate polymer will be polycarbonate, since computer housings are typically made of carbon composites of this type of polymer. A new experimental copolymer was used last year to generate electrically-conductive and thermal films with HiPco at 50/50 wt/wt composition. This will be one of the possible formulations. Reference films will be base polycarbonate and neat HiPco onto polycarbonate films. Other coating materials that will be tried will be based on HiPco composites with commercial enamels (polyurethane, acrylic, polyester), which could be compatible with the polycarbonate substrate. Nanosilica fibers are planned for possible use as thermal protection tiles on the shuttle orbiter. Right now, microscale silica is used. Going to the nanoscale will increase the surface-volume-per-unit-area of radiative heat dissipation. Nanoscale carbon fibers/nanotubes can be used as templates for the generation of nanosilica. A sol-gel operation is employed for this purpose.

  12. Man/computer communication in a space environment

    NASA Technical Reports Server (NTRS)

    Hodges, B. C.; Montoya, G.

    1973-01-01

    The present work reports on a study of the technology required to advance the state of the art in man/machine communications. The study involved the development and demonstration of both hardware and software to effectively implement man/computer interactive channels of communication. While tactile and visual man/computer communications equipment are standard methods of interaction with machines, man's speech is a natural media for inquiry and control. As part of this study, a word recognition unit was developed capable of recognizing a minimum of one hundred different words or sentences in any one of the currently used conversational languages. The study has proven that efficiency in communication between man and computer can be achieved when the vocabulary to be used is structured in a manner compatible with the rigid communication requirements of the machine while at the same time responsive to the informational needs of the man.

  13. Pollen Acceptance or Rejection: A Tale of Two Pathways.

    PubMed

    Doucet, Jennifer; Lee, Hyun Kyung; Goring, Daphne R

    2016-12-01

    While the molecular and cellular basis of self-incompatibility leading to self-pollen rejection in the Brassicaceae has been extensively studied, relatively little attention has been paid to compatible pollen recognition and the corresponding cellular responses in the stigmatic papillae. This is now changing because research has started to uncover steps in the Brassicaceae 'basal compatible pollen response pathway' in the stigma leading to pollen hydration and germination. Furthermore, recent studies suggest that self-incompatible pollen activates both the basal compatible pathway and the self-incompatibility pathway in the stigma, with the self-incompatibility response ultimately prevailing to reject self-pollen. We review here recent discoveries in both pathways and discuss how compatible pollen is accepted by the stigma versus the rejection of self-incompatible pollen. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Comparative serological investigation between cat and tiger blood for transfusion

    PubMed Central

    THENGCHAISRI, Naris; SINTHUSINGHA, Chayakrit; ARTHITWONG, Surapong; SATTASATHUCHANA, Panpicha

    2017-01-01

    Evidence suggests that non-domesticated felids inherited the same AB-erythrocyte antigens as domestic cats. To study the possible compatibility of tiger blood with that of other endangered felidae, blood samples from captive tigers and domestic cats were subjected to an in vitro study. The objectives of this study were to (1) identify whether the captive tigers had blood type AB and (2) determine the compatibility between the blood of captive tigers and that of domestic cats with a similar blood type. The anti-coagulated blood with ethylenediaminetetraacetic acid of 30 tigers was examined to determine blood type, and a crossmatching test was performed between tiger and cat blood. All 30 tigers had blood type A. Tube agglutination tests using tiger plasma with cat erythrocytes resulted in 100% agglutination (n=30) with type B cat erythrocytes and 76.7% agglutination (n=23) with type A cat erythrocytes. The 80% of major and 60% of minor compatibilities between blood from 10 tigers and 10 domestic cats with blood type A were found to pass compatibility tests. Interestingly, 3/10 of the tigers’ red blood cell samples were fully compatible with all cat plasmas, and 1/10 of the tiger plasma samples were fully compatible with the type A red cells of domestic cats. Although the result of present findings revealed type-A blood group in the surveyed tigers, the reaction of tiger plasma with Type-A red cell from cats suggested a possibility of other blood type in tigers. PMID:28450662

  15. Comparative serological investigation between cat and tiger blood for transfusion.

    PubMed

    Thengchaisri, Naris; Sinthusingha, Chayakrit; Arthitwong, Surapong; Sattasathuchana, Panpicha

    2017-06-29

    Evidence suggests that non-domesticated felids inherited the same AB-erythrocyte antigens as domestic cats. To study the possible compatibility of tiger blood with that of other endangered felidae, blood samples from captive tigers and domestic cats were subjected to an in vitro study. The objectives of this study were to (1) identify whether the captive tigers had blood type AB and (2) determine the compatibility between the blood of captive tigers and that of domestic cats with a similar blood type. The anti-coagulated blood with ethylenediaminetetraacetic acid of 30 tigers was examined to determine blood type, and a crossmatching test was performed between tiger and cat blood. All 30 tigers had blood type A. Tube agglutination tests using tiger plasma with cat erythrocytes resulted in 100% agglutination (n=30) with type B cat erythrocytes and 76.7% agglutination (n=23) with type A cat erythrocytes. The 80% of major and 60% of minor compatibilities between blood from 10 tigers and 10 domestic cats with blood type A were found to pass compatibility tests. Interestingly, 3/10 of the tigers' red blood cell samples were fully compatible with all cat plasmas, and 1/10 of the tiger plasma samples were fully compatible with the type A red cells of domestic cats. Although the result of present findings revealed type-A blood group in the surveyed tigers, the reaction of tiger plasma with Type-A red cell from cats suggested a possibility of other blood type in tigers.

  16. The Influence of Aconitum carmichaelii Debx. on the Pharmacokinetic Characteristics of Main Components in Rheum palmatum L.

    PubMed

    Li, Yun-xia; Gong, Xiao-hong; Li, Yan; Zhang, Ruo-qi; Yuan, An; Zhao, Meng-jie; Zeng, Dai-wen; Peng, Cheng

    2015-08-01

    Rhei Radix et Rhizoma was one of the commonly used traditional Chinese medicines, and the compatibility of Rhei Radix et Rhizoma and Aconiti Lateralis Radix Praeparata was the basic herb pair applied in many Chinese traditional prescription. Rhubarb anthraquinones were the main bioactive materials of Rhei Radix et Rhizoma. To elucidate the compatibility of Rhei Radix et Rhizoma and Aconiti Lateralis Radix Praeparata, the pharmacokinetics of rhubarb anthraquinones as the main marker constituents were investigated. In the present study, pharmacokinetic differences of rhubarb anthraquinones were detected after oral administration of extract of Rheum palmatum L. and compatibility with Aconitum carmichaelii Debx. After oral administration, no difference of peak time can be found for anthraquinones between rhubarb group and compatibility group. But Cmax and area under the curve of aloe-emodin, emodin and chrysophanol in compatibility group were significantly higher than that in rhubarb group. Although the Cmax of rhein in compatibility group was much lower than that in rhubarb group, the area under the curve value was similar in two groups. The clearance and t1/2 of rhubarb anthraquinone were also changed after compatibility. The change of pharmacokinetics characteristics of rhubarb anthraquinone after compatibility may be caused by the drug-drug interaction medicated by chemical reaction and cytochromes P450. Copyright © 2015 John Wiley & Sons, Ltd.

  17. Differentiating sepsis from non-infectious systemic inflammation based on microvesicle-bacteria aggregation

    NASA Astrophysics Data System (ADS)

    Herrmann, I. K.; Bertazzo, S.; O'Callaghan, D. J. P.; Schlegel, A. A.; Kallepitis, C.; Antcliffe, D. B.; Gordon, A. C.; Stevens, M. M.

    2015-08-01

    Sepsis is a severe medical condition and a leading cause of hospital mortality. Prompt diagnosis and early treatment has a significant, positive impact on patient outcome. However, sepsis is not always easy to diagnose, especially in critically ill patients. Here, we present a conceptionally new approach for the rapid diagnostic differentiation of sepsis from non-septic intensive care unit patients. Using advanced microscopy and spectroscopy techniques, we measure infection-specific changes in the activity of nano-sized cell-derived microvesicles to bind bacteria. We report on the use of a point-of-care-compatible microfluidic chip to measure microvesicle-bacteria aggregation and demonstrate rapid (<=1.5 hour) and reliable diagnostic differentiation of bacterial infection from non-infectious inflammation in a double-blind pilot study. Our study demonstrates the potential of microvesicle activities for sepsis diagnosis and introduces microvesicle-bacteria aggregation as a potentially useful parameter for making early clinical management decisions.Sepsis is a severe medical condition and a leading cause of hospital mortality. Prompt diagnosis and early treatment has a significant, positive impact on patient outcome. However, sepsis is not always easy to diagnose, especially in critically ill patients. Here, we present a conceptionally new approach for the rapid diagnostic differentiation of sepsis from non-septic intensive care unit patients. Using advanced microscopy and spectroscopy techniques, we measure infection-specific changes in the activity of nano-sized cell-derived microvesicles to bind bacteria. We report on the use of a point-of-care-compatible microfluidic chip to measure microvesicle-bacteria aggregation and demonstrate rapid (<=1.5 hour) and reliable diagnostic differentiation of bacterial infection from non-infectious inflammation in a double-blind pilot study. Our study demonstrates the potential of microvesicle activities for sepsis diagnosis and introduces microvesicle-bacteria aggregation as a potentially useful parameter for making early clinical management decisions. Electronic supplementary information (ESI) available: Fig. S1: Markers of inflammation and microvesicle characteristics in patient plasma samples, Fig. S2: Experimental sepsis model, Table S1: Patient characteristics. Table S2: Inclusion/exclusion criteria. See DOI: 10.1039/c5nr01851j

  18. The diffusion of evidence-based decision making among local health department practitioners in the United States.

    PubMed

    Harris, Jenine K; Erwin, Paul C; Smith, Carson; Brownson, Ross C

    2015-01-01

    Evidence-based decision making (EBDM) is the process, in local health departments (LHDs) and other settings, of translating the best available scientific evidence into practice. Local health departments are more likely to be successful if they use evidence-based strategies. However, EBDM and use of evidence-based strategies by LHDs are not widespread. Drawing on diffusion of innovations theory, we sought to understand how LHD directors and program managers perceive the relative advantage, compatibility, simplicity, and testability of EBDM. Directors and managers of programs in chronic disease, environmental health, and infectious disease from LHDs nationwide completed a survey including demographic information and questions about diffusion attributes (advantage, compatibility, simplicity, and testability) related to EBDM. Bivariate inferential tests were used to compare responses between directors and managers and to examine associations between participant characteristics and diffusion attributes. Relative advantage and compatibility scores were high for directors and managers, whereas simplicity and testability scores were lower. Although health department directors and managers of programs in chronic disease generally had higher scores than other groups, there were few significant or large differences between directors and managers across the diffusion attributes. Larger jurisdiction population size was associated with higher relative advantage and compatibility scores for both directors and managers. Overall, directors and managers were in strong agreement on the relative advantage of an LHD using EBDM, with directors in stronger agreement than managers. Perceived relative advantage has been demonstrated to be the most important factor in the rate of innovation adoption, suggesting an opportunity for directors to speed EBDM adoption. However, lower average scores across all groups for simplicity and testability may be hindering EBDM adoption. Recommended strategies for increasing perceived EBDM simplicity and testability are provided.

  19. Neuronal codes for the inhibitory control of impulsive actions in the rat infralimbic cortex.

    PubMed

    Tsutsui-Kimura, Iku; Ohmura, Yu; Izumi, Takeshi; Matsushima, Toshiya; Amita, Hidetoshi; Yamaguchi, Taku; Yoshida, Takayuki; Yoshioka, Mitsuhiro

    2016-01-01

    Poor impulse control is a debilitating condition observed in various psychiatric disorders and could be a risk factor for drug addiction, criminal involvement, and suicide. The rat infralimbic cortex (IL), located in the ventral portion of the medial prefrontal cortex, has been implicated in impulse control. To elucidate the neurophysiological basis of impulse control, we recorded single unit activity in the IL of a rat performing a 3-choiceserial reaction time task (3-CSRTT) and 2-choice task (2-CT), which are animal models for impulsivity. The inactivation of IL neuronal activity with an injection of muscimol (0.1 μg /side) disrupted impulse control in the 3-CSRTT. More than 60% (38/56) of isolated IL units were linked to impulse control, while approximately 30% of all units were linked to attentional function in the 3-CSRTT. To avoid confounding motor-related units with the impulse control-related units, we further conducted the 2-CT in which the animals' motor activities were restricted during recording window. More than 30% (14/44) of recorded IL units were linked to impulse control in the 2-CT. Several types of impulse control-related units were identified. Only 16% of all units were compatible with the results of the muscimol experiment, which showed a transient decline in the firing rate immediately before the release of behavioral inhibition. This is the first study to elucidate the neurophysiological basis of impulse control in the IL and to propose that IL neurons control impulsive actions in a more complex manner than previously considered. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Gender Compatibility, Math-Gender Stereotypes, and Self-Concepts in Math and Physics

    ERIC Educational Resources Information Center

    Koul, Ravinder; Lerdpornkulrat, Thanita; Poondej, Chanut

    2016-01-01

    Positive self-assessment of ability in the quantitative domains is considered critical for student participation in science, technology, engineering, and mathematics field studies. The present study investigated associations of gender compatibility (gender typicality and contentedness) and math-gender stereotypes with self-concepts in math and…

  1. Advanced subsonic long-haul transport terminal area compatibility study. Volume 2: Research and technology recommendations

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The Terminal Area Compatibility (TAC) study is briefly summarized for background information. The most important research items for the areas of noise congestion, and emissions are identified. Other key research areas are also discussed. The 50 recommended research items are categorized by flight phase, technology, and compatibility benefits. The relationship of the TAC recommendations to the previous ATT recommendations is discussed. The bulk of the document contains the 50 recommended research items. For each item, the potential payoff, state of readiness, recommended action and estimated cost and schedule are given.

  2. Advanced subsonic long-haul transport terminal area compatibility study. Volume 1: Compatibility assessment

    NASA Technical Reports Server (NTRS)

    1974-01-01

    An analysis was made to identify airplane research and technology necessary to ensure advanced transport aircraft the capability of accommodating forecast traffic without adverse impact on airport communities. Projections were made of the delay, noise, and emissions impact of future aircraft fleets on typical large urban airport. Design requirements, based on these projections, were developed for an advanced technology, long-haul, subsonic transport. A baseline aircraft was modified to fulfill the design requirements for terminal area compatibility. Technical and economic comparisons were made between these and other aircraft configured to support the study.

  3. Studies on in vitro biostability and blood compatibility of polyurethane potting compound based on aromatic polymeric MDI for extracorporeal devices.

    PubMed

    Hridya, V K; Jayabalan, M

    2009-12-01

    Polyurethane potting compound based on aromatic isocyanurate of polymeric MDI, poly propylene glycol (PPG400) and trimethylol propane (TMP) has significant favourable properties, good pot life and setting characteristics. The cured potting compound of this formulation has appreciable thermal stability and mechanical properties. In vitro biostability of cured potting compound has been found to be excellent without any significant degradation in simulated physiological media and chemical environment. Studies on blood-material interaction and cytotoxicity reveal in vitro blood compatibility and compatibility with cells of this potting compound.

  4. Communications Network

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The Multi-Compatible Network Interface Unit (MCNIU) is intended to connect the space station's communications and tracking, guidance and navigation, life support, electric power, payload data, hand controls, display consoles and other systems, and also communicate with diverse processors. Honeywell is now marketing MCNIU commercially. It has applicability in certain military operations or civil control centers. It has nongovernment utility among large companies, universities and research organizations that transfer large amounts of data among workstations and computers. *This product is no longer commercially available.

  5. Programmer/Analyst Guide for the Army Unit Resiliency Analysis (AURA) computer Simulation Model. Volume 1. AURA Methodology

    DTIC Science & Technology

    1990-10-01

    involving a heavy artillery barrage, the impact point output alone could consume upwards of 10,000 pages of computer paper. For this reason, AURA provides...but pervasive factor: the asset allocation model must be compatible with the mathematical behavior of the input data. Thus, for example, if assets are...described as expendable during repair or decontamination activities, it must have HOMELINKS which appear in the consuming repair SUBCHAINs

  6. Guidance Document for Alternative Diesel Fuels Proposed as Drop-In Fuels to Displace Diesel Fuels as Specified By ASTM Specification D975

    DTIC Science & Technology

    2014-07-01

    Interfacial Tension .................................9 3.2.10 Compatibility with Petroleum Diesel and Biodiesel ...Shorthand indication of percentage of biodiesel in a biodiesel blend CFPP – ASTM D6371 Cold Filter Plugging Point DOE – United States Department of...approved in 1949. However, as we have learned with biodiesel , the properties in D975 are not always sufficient to describe a fuel (or fuel component

  7. Design of an MR-compatible fNIRS instrument

    NASA Astrophysics Data System (ADS)

    Emir, Uzay; Ademoglu, Ahmet; Ozturk, Cengizhan; Aydin, Kubilay; Demiralp, Tamer; Kurt, Adnan; Dincer, Alp; Akin, Ata

    2005-04-01

    Acquiring functional near infrared spectroscopy (fNIRS) and functional magnetic resonance-imaging (fMRI) data are usually done asynchronously. In order to correlate these two different modalities" data, measurements must be performed at the same time. In this study, we have designed a new MR compatible continuous wave intensity based fNIRS device to overcome this problem. For MR compatible fNIRS, we used two LEDs with wavelengths at 660 and 870 nm. There are four photodiodes for light detection. LEDs operated in a sequential multiplexing mode with adjustable "on" time for each LED. Emitted and diffused light was transferred to and from the tissue through 10 m long single mode plastic optical fibers (INDUSTRIAL FIBER OPTICS, INC.). By using fibers, we overcome MR compatibility problems that can be caused by semi-conductors on probe. This MR compatible fNIRS design can provide synchronous measurements with low cost.

  8. Spatial compatibility and affordance compatibility in patients with chronic schizophrenia.

    PubMed

    Kume, Yu; Sato, Fumiyasu; Hiraoka, Yuya; Suzuki, Shingo; Niyama, Yoshitsugu

    2016-12-01

    A deterioration in information-processing performance is commonly recognized in patients with chronic schizophrenia. Although the enhancement of cognitive skills in patients with schizophrenia is important, the types of external stimuli that influence performance have not received much attention. The aim of present study was to clarify the effects of spatial and affordance compatibility in patients with schizophrenia, compared with those in healthy people. The subjects (25 patients with schizophrenia and 25 healthy controls) participated in two experiment examining the effects of the spatial location of stimuli and the action-relevance of objects. The results showed that the effect of spatial compatibility was similar in both the patients and the controls, whereas the influence of action-relevant objects was not highlighted in either patients with chronic schizophrenia or healthy controls. These findings provide important evidence of a normal spatial compatibility effect in patients with chronic schizophrenia. However, further research examining the affordance compatibility effect is needed, taking into consideration the symptomatology and the severity of the social functioning level in patients with schizophrenia. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Space-Shuttle Emulator Software

    NASA Technical Reports Server (NTRS)

    Arnold, Scott; Askew, Bill; Barry, Matthew R.; Leigh, Agnes; Mermelstein, Scott; Owens, James; Payne, Dan; Pemble, Jim; Sollinger, John; Thompson, Hiram; hide

    2007-01-01

    A package of software has been developed to execute a raw binary image of the space shuttle flight software for simulation of the computational effects of operation of space shuttle avionics. This software can be run on inexpensive computer workstations. Heretofore, it was necessary to use real flight computers to perform such tests and simulations. The package includes a program that emulates the space shuttle orbiter general- purpose computer [consisting of a central processing unit (CPU), input/output processor (IOP), master sequence controller, and buscontrol elements]; an emulator of the orbiter display electronics unit and models of the associated cathode-ray tubes, keyboards, and switch controls; computational models of the data-bus network; computational models of the multiplexer-demultiplexer components; an emulation of the pulse-code modulation master unit; an emulation of the payload data interleaver; a model of the master timing unit; a model of the mass memory unit; and a software component that ensures compatibility of telemetry and command services between the simulated space shuttle avionics and a mission control center. The software package is portable to several host platforms.

  10. Note: Commercial SQUID magnetometer-compatible NMR probe and its application for studying a quantum magnet.

    PubMed

    Vennemann, T; Jeong, M; Yoon, D; Magrez, A; Berger, H; Yang, L; Živković, I; Babkevich, P; Rønnow, H M

    2018-04-01

    We present a compact nuclear magnetic resonance (NMR) probe which is compatible with a magnet of a commercial superconducting quantum interference device magnetometer and demonstrate its application to the study of a quantum magnet. We employ trimmer chip capacitors to construct an NMR tank circuit for low temperature measurements. Using a magnetic insulator MoOPO 4 with S = 1/2 (Mo 5+ ) as an example, we show that the T-dependence of the circuit is weak enough to allow the ligand-ion NMR study of magnetic systems. Our 31 P NMR results are compatible with previous bulk susceptibility and neutron scattering experiments and furthermore reveal unconventional spin dynamics.

  11. Note: Commercial SQUID magnetometer-compatible NMR probe and its application for studying a quantum magnet

    NASA Astrophysics Data System (ADS)

    Vennemann, T.; Jeong, M.; Yoon, D.; Magrez, A.; Berger, H.; Yang, L.; Živković, I.; Babkevich, P.; Rønnow, H. M.

    2018-04-01

    We present a compact nuclear magnetic resonance (NMR) probe which is compatible with a magnet of a commercial superconducting quantum interference device magnetometer and demonstrate its application to the study of a quantum magnet. We employ trimmer chip capacitors to construct an NMR tank circuit for low temperature measurements. Using a magnetic insulator MoOPO4 with S = 1/2 (Mo5+) as an example, we show that the T-dependence of the circuit is weak enough to allow the ligand-ion NMR study of magnetic systems. Our 31P NMR results are compatible with previous bulk susceptibility and neutron scattering experiments and furthermore reveal unconventional spin dynamics.

  12. Discovery of Hyperpolarized Molecular Imaging Biomarkers in a Novel Prostate Tissue Slice Culture Model

    DTIC Science & Technology

    2013-06-01

    research is to optimize an MRS-compatible, 3D Tissue Culture Bioreactor for use with primary human prostate tissue cultures (TSCs) and use it to...Tissue Culture Bioreactor ” to be submitted to the Journal Magnetic Resonance in Medicine. CONCLUSIONS: We have engineered a robust MR compatible 3D ...loss of structure, function or metabolism within a NMR compatible 3-D tissue culture bioreactor , and that magnetic resonance spectroscopy studies of

  13. Low-frequency dielectric spectroscopy as a tool for studying the compatibility between pharmaceutical gels and mucous tissue.

    PubMed

    Hägerström, Helene; Edsman, Katarina; Strømme, Maria

    2003-09-01

    This interdisciplinary work demonstrates how low-frequency dielectric spectroscopy, a technique that is frequently used within physics, can be used to assess the possibilities of intimate surface contact between a polymer gel and mucous tissue, which is generally considered to be the first step in the mucoadhesion process. The dielectric responses of five different gels, of freshly excised porcine nasal mucosa and of systems made by combining the two were measured. All spectra were modeled by a Randles electric circuit containing a diffusion element, a barrier resistance in parallel with a capacitance, and a high-frequency resistance. The results were used to create a measure of the compatibility between the gel and the mucus, which we have named the compatibility factor. Thus, the compatibility factor provides us with a measure of the ease with which a charged species passes the interface between a gel and the mucus layer. The compatibility factor is calculated from the high frequency (kHz region) response of the gel, of the mucosa, and of the combined system. The two highest compatibility factors in this study were obtained for gels based on crosslinked poly(acrylic acid) and chitosan, which was in agreement with the results from mucoadhesion measurements that were performed using a tensile strength method. Copyright 2003 Wiley-Liss, Inc. and the American Pharmacists Association

  14. [Applications of mathematical statistics methods on compatibility researches of traditional Chinese medicines formulae].

    PubMed

    Mai, Lan-Yin; Li, Yi-Xuan; Chen, Yong; Xie, Zhen; Li, Jie; Zhong, Ming-Yu

    2014-05-01

    The compatibility of traditional Chinese medicines (TCMs) formulae containing enormous information, is a complex component system. Applications of mathematical statistics methods on the compatibility researches of traditional Chinese medicines formulae have great significance for promoting the modernization of traditional Chinese medicines and improving clinical efficacies and optimizations of formulae. As a tool for quantitative analysis, data inference and exploring inherent rules of substances, the mathematical statistics method can be used to reveal the working mechanisms of the compatibility of traditional Chinese medicines formulae in qualitatively and quantitatively. By reviewing studies based on the applications of mathematical statistics methods, this paper were summarized from perspective of dosages optimization, efficacies and changes of chemical components as well as the rules of incompatibility and contraindication of formulae, will provide the references for further studying and revealing the working mechanisms and the connotations of traditional Chinese medicines.

  15. Bacterial toxicity/compatibility of platinum nanospheres, nanocuboids and nanoflowers

    PubMed Central

    Gopal, Judy; Hasan, Nazim; Manikandan, M.; Wu, Hui-Fen

    2013-01-01

    For the first time, we have investigated the bacterial toxicity or compatibility properties of Pt nanoparticles (NPs) with different sizes (P1, P2, P3, P4 and P5). The bacterio-toxic or compatible properties of these five different sized Pt NPs with the clinical pathogen, Pseudomonas aeruginosa were explored by many analytical methods such as the conventional plate count method, matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS), fluorescence microscopy and fluorescence sensoring techniques. The results revealed that the 1–3 nm sized (P1 and P2) Pt NPs showed bacterio-toxic properties while the 4–21 nm (P3, P4 and P5) Pt NPs exhibited bacterio-compatible properties. This is the first study which reports the bacterial toxicity of Pt NPs. The information released from this study is significantly important to future clinical, medical, biological and biomedical applications of Pt NPs. PMID:23405274

  16. Ground Operations Aerospace Language (GOAL). Volume 3: Data bank

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The GOAL (Ground Operations Aerospace Language) test programming language was developed for use in ground checkout operations in a space vehicle launch environment. To insure compatibility with a maximum number of applications, a systematic and error-free method of referencing command/response (analog and digital) hardware measurements is a principle feature of the language. Central to the concept of requiring the test language to be independent of launch complex equipment and terminology is that of addressing measurements via symbolic names that have meaning directly in the hardware units being tested. To form the link from test program through test system interfaces to the units being tested the concept of a data bank has been introduced. The data bank is actually a large cross-reference table that provides pertinent hardware data such as interface unit addresses, data bus routings, or any other system values required to locate and access measurements.

  17. A STUDY OF SMALL GROUP DYNAMICS AND PRODUCTIVITY IN THE BSCS LABORATORY BLOCK PROGRAM.

    ERIC Educational Resources Information Center

    HURD, PAUL DEHART; ROWE, MARY BUDD

    THE RELATIONSHIP BETWEEN SMALL GROUP COMPATIBILITY AND ACHIEVEMENT IN THE BIOLOGICAL SCIENCE CURRICULUM STUDY LABORATORY BLOCK PROGRAM WAS TESTED. STUDENTS IN 14 CLASSES FROM FOUR HIGH SCHOOLS WERE ASSIGNED TO FOUR-MEMBER LABORATORY GROUPS CLASSIFIED AS COMPATIBLE OR INCOMPATIBLE. GROUP CLASSIFICATION WAS VALIDATED BY OBSERVERS WHO WERE NOT AWARE…

  18. Building America Case Study: Assessment of a Hybrid Retrofit Gas Water Heater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    This project completed a modeling evaluation of a hybrid gas water heater that combines a reduced capacity tankless unit with a downsized storage tank. This product would meet a significant market need by providing a higher efficiency gas water heater solution for retrofit applications while maintaining compatibility with the half-inch gas lines and standard B vents found in most homes. The TRNSYS simulation tool was used to model a base case 0.60 EF atmospheric gas storage water, a 0.82 EF non-condensing gas tankless water heater, an existing (high capacity) hybrid unit on the market, and an alternative hybrid unit withmore » lower storage volume and reduced gas input requirements. Simulations were completed under a 'peak day' sizing scenario with 183 gpd hot water loads in a Minnesota winter climate case. Full-year simulations were then completed in three climates (ranging from Phoenix to Minneapolis) for three hot water load scenarios (36, 57, and 96 gpd). Model projections indicate that the alternative hybrid offers an average 4.5% efficiency improvement relative to the 0.60 EF gas storage unit across all scenarios modeled. The alternative hybrid water heater evaluated does show promise, but the current low cost of natural gas across much of the country and the relatively small incremental efficiency improvement poses challenges in initially building a market demand for the product.« less

  19. Investigation of the relationship between illogical thoughts and dependence on others and marriage compatibility in the Iranian Veterans exposed to chemicals in Iran-Iraq War.

    PubMed

    Afkar, A H; Mahbobubi, M; Neyakan Shahri, M; Mohammadi, M; Jalilian, F; Moradi, F

    2014-05-08

    Marital satisfaction is one of the main determinants of a family's correct function. A large number of veterans have been reported to suffer from depression, anxiety, mood disorders, post-traumatic stress disorder, and physical disorders. The objective of this study is to examine association between Illogical thoughts and Dependence on Others and Marriage Compatibility in the Iranian Veterans Exposed to Chemicals in Iran-Iraq War. The present cross-sectional, analytical study was conducted on 200 veterans exposed to chemicals who were covered by the Foundation of Martyrs and Veterans Affairs, Gilangharb, Kermanshah, Iran. The study sample size was determined according to Krejcie and Morgan formula and the subjects were selected through random sampling. The study data were collected using marriage compatibility questionnaire, illogical thoughts questionnaire, and dependence on others questionnaire. The study data were analyzed using the SPSS statistical software (version18). Pearson correlation coefficient, multiple regression, and t-test were used in order to determine the relationships among the variables and compare the means. The findings of the current study revealed no significant relationship between dependence on others, anxious attention, helplessness, avoiding problems, perfectionism, and autonomy and marriage compatibility. However, a significant relationship was found between failure and marriage compatibility. Overall, the findings of the present study showed that the veterans of Gilangharb did not have disorders, but depended on others, particularly their spouses, due to their abnormal physical status. Sometimes, they cannot even do their personal tasks which results in their dependence on others eventually putting the veterans under pressure and stress.

  20. HAN-Based Monopropellant Technology Development

    NASA Technical Reports Server (NTRS)

    Reed, Brian

    2002-01-01

    NASA Glenn Research Center is sponsoring efforts to develop technology for high-performance, high-density, low-freezing point, low-hazards monopropellant systems. The program is focused on a family of monopropellant formulations composed of an aqueous solution of hydroxylammonium nitrate (HAN) and a fuel component. HAN-based monopropellants offer significant mass and volume savings to small (less than 100 kg) satellite for orbit raising and on-orbit propulsion applications. The low-hazards characteristics of HAN-based monopropellants make them attractive for applications where ground processing costs are a significant concern. A 1-lbf thruster has been demonstrated to a 20-kg satellite orbit insertion duty cycle, using a formulation compatible with currently available catalysts. To achieve specific impulse levels above those of hydrazine, catalyst materials that can withstand the high-temperature, corrosive combustion environment of HAN-based monopropellants have to be developed. There also needs to be work done to characterize propellant properties, burning behavior, and material compatibility. NASA is coordinating their monopropellant efforts with those of the United States Air Force.

  1. Advanced radiology information system.

    PubMed

    Kolovou, L; Vatousi, M; Lymperopoulos, D; Koukias, M

    2005-01-01

    The innovative features of an advanced Radiology Information System (RIS) are presented in this paper. The interoperability of RIS with the other Intra-hospital Information Systems that interacts with, dealing with the compatibility and open architecture issues, are accomplished by two novel mechanisms [1]. The first one is the particular message handling system that is applied for the exchange of information, according to the Health Level Seven (HL7) protocol's specifications and serves the transfer of medical and administrative data among the RIS applications and data store unit. The same mechanism allows the secure and HL7-compatible interactions with the Hospital Information System (HIS) too. The second one implements the translation of information between the formats that HL7 and Digital Imaging and Communication in Medicine (DICOM) protocols specify, providing the communication between RIS and Picture and Archive Communication System (PACS). The whole structure ensures the automation of the every-day procedures that the ;medical protocol' specifies and provides its services through a friendly and easy to manage graphical user interface.

  2. [A proposal for introduction of Europeristat-compatible information system aiming a unified quality control of obstetrical and perinatological care in Hungary].

    PubMed

    Berkő, Péter

    2016-05-01

    It is a regrettable deficiency in the Hungarian healthcare that the culture and the system of quality control of cure have not been formed (except for a few subspecialties, units or wards). If hospital wards do not have a national, professionally unified and modern information system presenting the most important quantity and quality indicators of their medicinal activity annually, a stable basis for definition of future tasks is absent. The author puts forward a proposal for the establishment of the information systems for different professional fields. On the basis of experience of perinatological information system operating for over 3 decades in Borsod-Abaúj-Zemplén county, he also proposes introduction of a nationally unified, Europeristat-compatible information system following Tauffer-statistics which may serve as a uniform quality control of obstetrics and perinatological care, as well as introduction of its base, the dataform "TePERA" (Form of Obstetrics and Perinatological Care Risk).

  3. Tailoring of TiO2 films by H2SO4 treatment and UV irradiation to improve anticoagulant ability and endothelial cell compatibility.

    PubMed

    Liao, Yuzhen; Li, Linhua; Chen, Jiang; Yang, Ping; Zhao, Ansha; Sun, Hong; Huang, Nan

    2017-07-01

    Surfaces with dual functions that simultaneously exhibit good anticoagulant ability and endothelial cell (EC) compatibility are desirable for blood contact materials. However, these dual functions have rarely been achieved by inorganic materials. In this study, titanium dioxide (TiO 2 ) films were treated by sulphuric acid (H 2 SO 4 ) and ultraviolet (UV) irradiation successively (TiO 2 H 2 SO 4 -UV), resulting in good anticoagulant ability and EC compatibility simultaneously. We found that UV irradiation improved the anticoagulant ability of TiO 2 films significantly while enhancing EC compatibility, though not significantly. The enhanced anticoagulant ability could be related to the oxidation of surface-adsorbed hydrocarbons and increased hydrophilicity. The H 2 SO 4 treatment improved the anticoagulant ability of TiO 2 films slightly, while UV irradiation improved the anticoagulant ability strongly. The enhanced EC compatibility could be related to the increased surface roughness and positive charges on the surface of the TiO 2 films. Furthermore, the time-dependent degradation of the enhanced EC compatibility and anticoagulant ability of TiO 2 H 2 SO 4 -UV was observed. In summary, TiO 2 H 2 SO 4 -UV expressed both excellent anticoagulant ability and good EC compatibility at the same time, which could be desirable for blood contact materials. However, the compatibility of TiO 2 H 2 SO 4 -UV with smooth muscle cells (SMCs) and macrophages was also improved. More effort is still needed to selectively improve EC compatibility on TiO 2 films for better re-endothelialization. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. The Rules of Variation Expanded, Implications for the Research on Compatible Genomics.

    PubMed

    Castro-Chavez, Fernando

    2011-05-12

    The main focus of this article is to present the practical aspect of the code rules of variation and the search for a second set of genomic rules, including comparison of sequences to understand how to preserve compatible organisms in danger of extinction and how to generate biodiversity. Three new rules of variation are introduced: 1) homologous recombination, 2) a healthy fertile offspring, and 3) comparison of compatible genomes. The novel search in the natural world for fully compatible genomes capable of homologous recombination is explored by using examples of human polymorphisms in the LDLRAP1 gene, and by the production of fertile offspring by crossbreeding. Examples of dogs, llamas and finches will be presented by a rational control of: natural crossbreeding of organisms with compatible genomes (something already happening in nature), the current work focuses on the generation of new varieties after a careful plan. This study is presented within the context of biosemiotics, which studies the processing of information, signaling and signs by living systems. I define a group of organisms having compatible genomes as a single theme: the genomic species or population, able to speak the same molecular language through different accents, with each variety within a theme being a different version of the same book. These studies have a molecular, compatible genetics context. Population and ecosystem biosemiotics will be exemplified by a possible genetic damage capable of causing mutations by breaking the rules of variation through the coordinated patterns of atoms present in the 9/11 World Trade Center contaminated dust (U, Ba, La, Ce, Sr, Rb, K, Mn, Mg, etc.), combination that may be able to overload the molecular quality control mechanisms of the human body. I introduce here the balance of codons in the circular genetic code: 2[1(1)+1(3)+1(4)+4(2)]=2[2(2)+3(4)].

  5. The Rules of Variation Expanded, Implications for the Research on Compatible Genomics

    PubMed Central

    Castro-Chavez, Fernando

    2011-01-01

    The main focus of this article is to present the practical aspect of the code rules of variation and the search for a second set of genomic rules, including comparison of sequences to understand how to preserve compatible organisms in danger of extinction and how to generate biodiversity. Three new rules of variation are introduced: 1) homologous recombination, 2) a healthy fertile offspring, and 3) comparison of compatible genomes. The novel search in the natural world for fully compatible genomes capable of homologous recombination is explored by using examples of human polymorphisms in the LDLRAP1 gene, and by the production of fertile offspring by crossbreeding. Examples of dogs, llamas and finches will be presented by a rational control of: natural crossbreeding of organisms with compatible genomes (something already happening in nature), the current work focuses on the generation of new varieties after a careful plan. This study is presented within the context of biosemiotics, which studies the processing of information, signaling and signs by living systems. I define a group of organisms having compatible genomes as a single theme: the genomic species or population, able to speak the same molecular language through different accents, with each variety within a theme being a different version of the same book. These studies have a molecular, compatible genetics context. Population and ecosystem biosemiotics will be exemplified by a possible genetic damage capable of causing mutations by breaking the rules of variation through the coordinated patterns of atoms present in the 9/11 World Trade Center contaminated dust (U, Ba, La, Ce, Sr, Rb, K, Mn, Mg, etc.), combination that may be able to overload the molecular quality control mechanisms of the human body. I introduce here the balance of codons in the circular genetic code: 2[1(1)+1(3)+1(4)+4(2)]=2[2(2)+3(4)]. PMID:21743816

  6. Herbal compatibility of traditional Chinese medical formulas for acquired immunodeficiency syndrome.

    PubMed

    Cui, Meng; Li, Jinghua; Li, Haiyan; Song, Chunxin

    2012-09-01

    Because herbal compatibility is one of the most important reasons why Traditional Chinese Medcine (TCM) formulas are effective for acquired immunodeficiency syndrome (AIDS), our study aimed to determine the compatibility of herbs based on published AIDS clinical research in Chinese periodicals. To achieve this aim, we designed a new data-mining algorithm according to TCM data characteristics. We found 25 clinical AIDS studies, all using Chinese herbs for treatment, in the Traditional Chinese Medicine Database System, and information on diagnosis and treatment was extracted. To find out herbal compatibility, especially the formulae for herbal combinations, we proposed an improved association rule algorithm based on the frequency of combinations. In this algorithm, all the compatibility relationships were displayed in a tree structure, by which the relationship between formulas and their derivation could be clearly inferred. Data analysis showed that approximately 100 herbs have been used for treating AIDS. Based on the whole herb compatibility tree, we calculated a basic formula for AIDS: Huang Qi combined with Ren Shen, Fu Ling, Bai Zhu, Bai Zhu, Dang Gui, and Bai Shao. This formula, deriving from most of clinical prescriptions, and was chosed by most of clinicians for AIDS treatment. From data mining we found that Qi replenishment and detoxification were the main treatment principles, which coincided with the AIDS pathological mechanism in which immune function is destroyed by human immunodeficiency virus (HIV). Our data-mining results suggest that the core TCM treatment of AIDS is replenishing Qi and detoxification, by which AIDS patients' immune system may be enhanced. Compatibility of Huang Qi with some frequently-used herbs have shown real efficacy in clinical practice, which warrants pharmacological research in the future.

  7. Theoretical and NMR conformational studies of β-proline oligopeptides with alternating chirality of pyrrolidine units

    NASA Astrophysics Data System (ADS)

    Mantsyzov, Alexey B.; Savelyev, Oleg Y.; Ivantcova, Polina M.; Bräse, Stefan; Kudryavtsev, Konstantin V.; Polshakov, Vladimir I.

    2018-03-01

    Synthetic β-peptides are potential functional mimetics of native α-proteins. A recently developed, novel, synthetic approach provides an effective route to the broad group of β-proline oligomers with alternating patterns of stereogenic centers. Conformation of the pyrrolidine ring, Z/E isomerism of β-peptide bonds, and hindered rotation of the neighboring monomers determine the spatial structure of this group of β-proline oligopeptides. Preferences in structural organization and corresponding thermodynamic properties are determined by NMR spectroscopy, restrained molecular dynamics and quantum mechanics. The studied β-proline oligopeptides exist in dimethyl sulfoxide solution in a limited number of conformers, with compatible energy of formation and different spatial organization. In the β-proline tetrapeptide with alternating chirality of composing pyrrolidine units, one of three peptide bonds may exist in an E configuration. For the alternating β-proline pentapeptide, the presence of an E configuration for at least of one β-peptide bond is mandatory. In this case, three peptide bonds synchronously change their configurations. Larger polypeptides may only exist in the presence of several E configurations of β-peptide bonds forming a wave-like extended structure.

  8. Are Physicians Likely to Adopt Emerging Mobile Technologies? Attitudes and Innovation Factors Affecting Smartphone Use in the Southeastern United States

    PubMed Central

    Putzer, Gavin J; Park, Yangil

    2012-01-01

    The smartphone has emerged as an important technological device to assist physicians with medical decision making, clinical tasks, and other computing functions. A smartphone is a device that combines mobile telecommunication with Internet accessibility as well as word processing. Moreover, smartphones have additional features such as applications pertinent to clinical medicine and practice management. The purpose of this study was to investigate the innovation factors that affect a physician's decision to adopt an emerging mobile technological device such as a smartphone. The study sample consisted of 103 physicians from community hospitals and academic medical centers in the southeastern United States. Innovation factors are elements that affect an individual's attitude toward using and adopting an emerging technology. In our model, the innovation characteristics of compatibility, job relevance, the internal environment, observability, personal experience, and the external environment were all significant predictors of attitude toward using a smartphone. These influential innovation factors presumably are salient predictors of a physician's attitude toward using a smartphone to assist with clinical tasks. Health information technology devices such as smartphones offer promise as a means to improve clinical efficiency, medical quality, and care coordination and possibly reduce healthcare costs. PMID:22737094

  9. Theoretical and NMR Conformational Studies of β-Proline Oligopeptides With Alternating Chirality of Pyrrolidine Units.

    PubMed

    Mantsyzov, Alexey B; Savelyev, Oleg Y; Ivantcova, Polina M; Bräse, Stefan; Kudryavtsev, Konstantin V; Polshakov, Vladimir I

    2018-01-01

    Synthetic β-peptides are potential functional mimetics of native α-proteins. A recently developed, novel, synthetic approach provides an effective route to the broad group of β-proline oligomers with alternating patterns of stereogenic centers. Conformation of the pyrrolidine ring, Z / E isomerism of β-peptide bonds, and hindered rotation of the neighboring monomers determine the spatial structure of this group of β-proline oligopeptides. Preferences in their structural organization and corresponding thermodynamic properties are determined by NMR spectroscopy, restrained molecular dynamics and quantum mechanics. The studied β-proline oligopeptides exist in dimethyl sulfoxide solution in a limited number of conformers, with compatible energy of formation and different spatial organization. In the β-proline tetrapeptide with alternating chirality of composing pyrrolidine units, one of three peptide bonds may exist in an E configuration. For the alternating β-proline pentapeptide, the presence of an E configuration for at least of one β-peptide bond is mandatory. In this case, three peptide bonds synchronously change their configurations. Larger polypeptides may only exist in the presence of several E configurations of β-peptide bonds forming a wave-like extended structure.

  10. RTO Meeting Proceedings 16, Aircraft Weapon System Compatibility and Integration held in Chester, United Kingdom, 28-30 September, 1998

    DTIC Science & Technology

    1999-04-01

    project, there was a requirement to place a camera behind a each photogrammetric target in the image and for each cylindrically curved window...testing. T by the wind tunnel’s captive trajectory sting, U.S. wing open effets on the o erthnd, h e Navyengneer h e obervd sgnifcan difereces wing...Flying Qualities, Symposium on Aeroballistics, May 1981. Aerodynamics, and Structures disciplines benefit directly 6. Magnus , A. E., and Epton, M. A

  11. Measure for measure

    NASA Astrophysics Data System (ADS)

    Weinberger, Peter

    2012-06-01

    The present system of measures for length, weight and capacity (volume) originates from scientific ideas expressed during the French Revolution in 1789. The history of a compatible unit of length, however, turns out to be less of a scientific but rather of a political character. Here reports to the Philosophical Magazine made in the first quarter of the nineteenth century are used to trace the cultural split between meters and inches, and between kilograms and pounds, that can be experienced in many parts of the world.

  12. Absorber for solar power.

    PubMed

    Powell, W R

    1974-10-01

    A simple, economical absorber utilizing a new principle of operation to achieve very low reradiation losses while generating temperatures limited by material properties of quartz is described. Its performance is analyzed and indicates approximately 90% thermal efficiency and 73% conversion efficiency for an earth based unit with moderately concentrated (~tenfold) sunlight incident. It is consequently compatible with the most economic of concentrator mirrors (stamped) or mirrors deployable in space. Space applications are particularly attractive, as temperatures significantly below 300 K are possible and permit even higher conversion efficiency.

  13. Reversible Thermoset Adhesives

    NASA Technical Reports Server (NTRS)

    Mac Murray, Benjamin C. (Inventor); Tong, Tat H. (Inventor); Hreha, Richard D. (Inventor)

    2016-01-01

    Embodiments of a reversible thermoset adhesive formed by incorporating thermally-reversible cross-linking units and a method for making the reversible thermoset adhesive are provided. One approach to formulating reversible thermoset adhesives includes incorporating dienes, such as furans, and dienophiles, such as maleimides, into a polymer network as reversible covalent cross-links using Diels Alder cross-link formation between the diene and dienophile. The chemical components may be selected based on their compatibility with adhesive chemistry as well as their ability to undergo controlled, reversible cross-linking chemistry.

  14. Apollo Soyuz test project, USA-USSR. [mission plan of spacecraft docking

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The mission plan of the docking of a United States Apollo and a Soviet Union Soyuz spacecraft in Earth orbit to test compatible rendezvous and docking equipment and procedures is presented. Space experiments conducted jointly by the astronauts and cosmonauts during the joint phase of the mission as well as experiments performed solely by the U.S. astronauts and spread over the nine day span of the flight are included. Biographies of the astronauts and cosmonauts are given.

  15. The SL SCAN-1: Fourier Domain Optical Coherence Tomography Integrated into a Slit Lamp

    NASA Astrophysics Data System (ADS)

    Verbraak, F. D.; Stehouwer, M.

    The detailed cross-sectional images of OCT can be used for diagnosis and follow-up, assessing therapeutic success or failure. Recently, the OCT technology has been implemented in a small unit compatible with existing slit lamps. This increases the efficiency of the routine clinical examination of a patient, will increase the comfort of the patient, and saves time. Additionally, the posterior segment can be scanned through a handheld lens and even through a three-mirror lens.

  16. Nanoelectronics enabled chronic multimodal neural platform in a mouse ischemic model

    PubMed Central

    Luan, Lan; Sullender, Colin T.; Li, Xue; Zhao, Zhengtuo; Zhu, Hanlin; Wei, Xiaoling; Xie, Chong; Dunn, Andrew K.

    2018-01-01

    Background Despite significant advancements of optical imaging techniques for mapping hemodynamics in small animal models, it remains challenging to combine imaging with spatially resolved electrical recording of individual neurons especially for longitudinal studies. This is largely due to the strong invasiveness to the living brain from the penetrating electrodes and their limited compatibility with longitudinal imaging. New Method We implant arrays of ultraflexible nanoelectronic threads (NETs) in mice for neural recording both at the brain surface and intracortically, which maintain great tissue compatibility chronically. By mounting a cranial window atop of the NET arrays that allows for chronic optical access, we establish a multimodal platform that combines spatially resolved electrical recording of neural activity and laser speckle contrast imaging (LSCI) of cerebral blood flow (CBF) for longitudinal studies. Results We induce peri-infarct depolarizations (PIDs) by targeted photothrombosis, and show the ability to detect its occurrence and propagation through spatiotemporal variations in both extracellular potentials and CBF. We also demonstrate chronic tracking of single-unit neural activity and CBF over days after photothrombosis, from which we observe reperfusion and increased firing rates. Comparison with Existing Method(s) This multimodal platform enables simultaneous mapping of neural activity and hemodynamic parameters at the microscale for quantitative, longitudinal comparisons with minimal perturbation to the baseline neurophysiology. Conclusion The ability to spatiotemporally resolve and chronically track CBF and neural electrical activity in the same living brain region has broad applications for studying the interplay between neural and hemodynamic responses in health and in cerebrovascular and neurological pathologies. PMID:29203409

  17. Compatibility Study of Nanofiltration and Reverse Osmosis Membranes with 1 Cyclohexylpiperidenium Bicarbonate Solutions

    DOE Data Explorer

    Adhikari, Birendra; Jones, Michael G.; Orme, Christopher J.; Wendt, Daniel S.; Wilson, Aaron D.

    2015-10-01

    The switchable polarity solvent forward osmosis (SPS FO) desalination process requires use of a polishing filtration step to remove trace quantities of draw solution from the product water stream. Selected nanofiltration (NF) and reverse osmosis (RO) membranes were tested for their ability to recover water from 1-cyclohexylpiperidenium bicarbonate solutions in this application. This submission includes the experimental data used to calculate NF and RO membrane flux-normalized net driving pressure (FNNDP) and flux-normalized rejection (FNR) performance in recovering water from 1-cyclohexylpiperidenium bicarbonate solutions. This data is further described and visualized in the manuscript entitled "Compatibility study of nanofiltration and reverse osmosis membranes with 1 cyclohexylpiperidenium bicarbonate solutions" (see attached Compatibility Study Manuscript).

  18. The Transcriptional Regulator, CosR, Controls Compatible Solute Biosynthesis and Transport, Motility and Biofilm Formation in Vibrio cholerae

    PubMed Central

    Shikuma, Nicholas J.; Davis, Kimberly R.; Fong, Jiunn N. C.; Yildiz, Fitnat H.

    2012-01-01

    SUMMARY Vibrio cholerae inhabits aquatic environments and colonizes the human digestive tract to cause the disease cholera. In these environments, V. cholerae copes with fluctuations in salinity and osmolarity by producing and transporting small, organic, highly soluble molecules called compatible solutes, which counteract extracellular osmotic pressure. Currently, it is unclear how V. cholerae regulates the expression of genes important for the biosynthesis or transport of compatible solutes in response to changing salinity or osmolarity conditions. Through a genome-wide transcriptional analysis of the salinity response of V. cholerae, we identified a transcriptional regulator we name CosR for compatible solute regulator. The expression of cosR is regulated by ionic strength and not osmolarity. A transcriptome analysis of a ΔcosR mutant revealed that CosR represses genes involved in ectoine biosynthesis and compatible solute transport in a salinity-dependent manner. When grown in salinities similar to estuarine environments, CosR activates biofilm formation and represses motility independently of its function as an ectoine regulator. This is the first study to characterize a compatible solute regulator in V. cholerae and couples the regulation of osmotic tolerance with biofilm formation and motility. PMID:22690884

  19. Simpler and equitable allocation of kidneys from postmortem donors primarily based on full HLA-DR compatibility.

    PubMed

    Doxiadis, Ilias I N; de Fijter, Johan W; Mallat, Marko J K; Haasnoot, Geert W; Ringers, Jan; Persijn, Guido G; Claas, Frans H J

    2007-05-15

    The introduction of human leukocyte antigen (HLA)-matching in nonliving kidney transplantation has resulted into a better graft outcome, but also in an increase of waiting time, especially for patients with rare HLA phenotypes. We addressed the question of the differential influence of HLA-DR-matching versus HLA-A,B in clinical kidney transplantation. We used Kaplan-Meier product limit method to estimate survival rates, and Cox proportional hazard regression for the estimation of relative risks (Hazard-ratios) for different variables. A single center study (n=456 transplants, performed between 1985 and 1999) showed that full HLA-DR compatibility leads to a lower incidence of biopsy confirmed acute rejections in the first 180 posttransplantation days. These results were substantiated using the Eurotransplant database (n=39,205 transplants performed between 1985 and 2005) where graft survival in the full HLA-DR compatible group was significantly better than in the incompatible. An additional positive effect of HLA-A,B matching was only found in the full HLA-DR compatible group. In both studies, the introduction of a single HLA-DR incompatibility eliminates the HLA-A,B matching effect. We propose to allocate postmortem kidneys only to patients with full HLA-DR compatibility, and use HLA-A,B compatibility as an additional selection criterion. All patients, irrespective of their ethnic origin, will profit since the polymorphism of HLA-DR is by far lower than that of HLA-A,B. Excessive kidney travel and cold ischemia time will be significantly reduced.

  20. Students' Studying and Approaches to Learning in Introductory Biology

    PubMed Central

    2004-01-01

    This exploratory study was conducted in an introductory biology course to determine 1) how students used the large lecture environment to create their own learning tasks during studying and 2) whether meaningful learning resulted from the students' efforts. Academic task research from the K–12 education literature and student approaches to learning research from the postsecondary education literature provided the theoretical framework for the mixed methods study. The subject topic was cell division. Findings showed that students 1) valued lectures to develop what they believed to be their own understanding of the topic; 2) deliberately created and engaged in learning tasks for themselves only in preparation for the unit exam; 3) used course resources, cognitive operations, and study strategies that were compatible with surface and strategic, rather than deep, approaches to learning; 4) successfully demonstrated competence in answering familiar test questions aligned with their surface and strategic approaches to studying and learning; and 5) demonstrated limited meaningful understanding of the significance of cell division processes. Implications for introductory biology education are discussed. PMID:15592598

  1. Small-Molecule Organic Photovoltaic Modules Fabricated via Halogen-Free Solvent System with Roll-to-Roll Compatible Scalable Printing Method.

    PubMed

    Heo, Youn-Jung; Jung, Yen-Sook; Hwang, Kyeongil; Kim, Jueng-Eun; Yeo, Jun-Seok; Lee, Sehyun; Jeon, Ye-Jin; Lee, Donmin; Kim, Dong-Yu

    2017-11-15

    For the first time, the photovoltaic modules composed of small molecule were successfully fabricated by using roll-to-roll compatible printing techniques. In this study, blend films of small molecules, BTR and PC 71 BM were slot-die coated using a halogen-free solvent system. As a result, high efficiencies of 7.46% and 6.56% were achieved from time-consuming solvent vapor annealing (SVA) treatment and roll-to-roll compatible solvent additive approaches, respectively. After successful verification of our roll-to-roll compatible method on small-area devices, we further fabricated large-area photovoltaic modules with a total active area of 10 cm 2 , achieving a power conversion efficiency (PCE) of 4.83%. This demonstration of large-area photovoltaic modules through roll-to-roll compatible printing methods, even based on a halogen-free solvent, suggests the great potential for the industrial-scale production of organic solar cells (OSCs).

  2. Inducing PLA/starch compatibility through butyl-etherification of waxy and high amylose starch.

    PubMed

    Wokadala, Obiro Cuthbert; Emmambux, Naushad Mohammad; Ray, Suprakas Sinha

    2014-11-04

    In this study, waxy and high amylose starches were modified through butyl-etherification to facilitate compatibility with polylactide (PLA). Fourier transform infrared spectroscopy, proton nuclear magnetic resonance spectroscopy and wettability tests showed that hydrophobic butyl-etherified waxy and high amylose starches were obtained with degree of substitution values of 2.0 and 2.1, respectively. Differential scanning calorimetry, tensile testing, and scanning electron microscopy (SEM) demonstrated improved PLA/starch compatibility for both waxy and high amylose starch after butyl-etherification. The PLA/butyl-etherified waxy and high amylose starch composite films had higher tensile strength and elongation at break compared to PLA/non-butyl-etherified composite films. The morphological study using SEM showed that PLA/butyl-etherified waxy starch composites had a more homogenous microstructure compared to PLA/butyl-etherified high amylose starch composites. Thermogravimetric analysis showed that PLA/starch composite thermal stability decreased with starch butyl-etherification for both waxy and high amylose starches. This study mainly demonstrates that PLA/starch compatibility can be improved through starch butyl-etherification. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Enhancing creativity: Proper body posture meets proper emotion.

    PubMed

    Hao, Ning; Xue, Hua; Yuan, Huan; Wang, Qing; Runco, Mark A

    2017-02-01

    This study tested whether compatibility or incompatibility between body posture and emotion was beneficial for creativity. In Study 1, participants were asked to solve the Alternative Uses Task (AUT) problems when performing open or closed body posture in positive or negative emotional state respectively. The results showed that originality of AUT performance was higher in the compatible conditions (i.e., open-positive and closed-negative) than in the incompatible conditions (i.e., closed-positive and open-negative). In Study 2, the compatibility effect was replicated in both the AUT and the Realistic Presented Problem test (i.e., RPP). Moreover, it was revealed that participants exhibited the highest associative flexibility in the open-positive condition, and the highest persistence in the closed-negative condition. These findings indicate that compatibility between body posture and emotion is beneficial for creativity. This may be because when the implicit emotions elicited by body posture match explicit emotions, the effects of emotions on creativity are enhanced, therefore promoting creativity through the flexibility or the persistence pathway respectively. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Therapist turnover and new program sustainability in mental health clinics as a function of organizational culture, climate, and service structure.

    PubMed

    Glisson, Charles; Schoenwald, Sonja K; Kelleher, Kelly; Landsverk, John; Hoagwood, Kimberly Eaton; Mayberg, Stephen; Green, Philip

    2008-03-01

    The present study incorporates organizational theory and organizational characteristics in examining issues related to the successful implementation of mental health services. Following the theoretical foundations of socio-technical and cultural models of organizational effectiveness, organizational climate, culture, legal and service structures, and workforce characteristics are examined as correlates of therapist turnover and new program sustainability in a nationwide sample of mental health clinics. Results of General Linear Modeling (GLM) with the organization as the unit of analysis revealed that organizations with the best climates as measured by the Organizational Social Context (OSC) profiling system, had annual turnover rates (10%) that were less than half the rates found in organizations with the worst climates (22%). In addition, organizations with the best culture profiles sustained new treatment or service programs over twice as long (50 vs. 24 months) as organizations with the worst cultures. Finally, clinics with separate children's services units had higher turnover rates than clinics that served adults and children within the same unit. The findings suggest that strategies to support the implementation of new mental health treatments and services should attend to organizational culture and climate, and to the compatibility of organizational service structures with the demand characteristics of treatments.

  5. Utilization of BIM for automation of quantity takeoffs and cost estimation in transport infrastructure construction projects in the Czech Republic

    NASA Astrophysics Data System (ADS)

    Vitásek, Stanislav; Matějka, Petr

    2017-09-01

    The article deals with problematic parts of automated processing of quantity takeoff (QTO) from data generated in BIM model. It focuses on models of road constructions, and uses volumes and dimensions of excavation work to create an estimate of construction costs. The article uses a case study and explorative methods to discuss possibilities and problems of data transfer from a model to a price system of construction production when such transfer is used for price estimates of construction works. Current QTOs and price tenders are made with 2D documents. This process is becoming obsolete because more modern tools can be used. The BIM phenomenon enables partial automation in processing volumes and dimensions of construction units and matching the data to units in a given price scheme. Therefore price of construction can be estimated and structured without lengthy and often imprecise manual calculations. The use of BIM for QTO is highly dependent on local market budgeting systems, therefore proper push/pull strategy is required. It also requires proper requirements specification, compatible pricing database and software.

  6. Development of Novel Piezoelectric Biosensor Using PZT Ceramic Resonator for Detection of Cancer Markers.

    PubMed

    Su, Li; Fong, Chi-Chun; Cheung, Pik-Yuan; Yang, Mengsu

    2017-01-01

    A novel biosensor based on piezoelectric ceramic resonator was developed for direct detection of cancer markers in the study. For the first time, a commercially available PZT ceramic resonator with high resonance frequency was utilized as transducer for a piezoelectric biosensor. A dual ceramic resonators scheme was designed wherein two ceramic resonators were connected in parallel: one resonator was used as the sensing unit and the other as the control unit. This arrangement minimizes environmental influences including temperature fluctuation, while achieving the required frequency stability for biosensing applications. The detection of the cancer markers Prostate Specific Antigen (PSA) and α-Fetoprotein (AFP) was carried out through frequency change measurement. The device showed high sensitivity (0.25 ng/ml) and fast detection (within 30 min) with small samples (1 μl), which is compatible with the requirements of clinical measurements. The results also showed that the ceramic resonator-based piezoelectric biosensor platform could be utilized with different chemical interfaces, and had the potential to be further developed into biosensor arrays with different specificities for simultaneous detection of multiple analytes.

  7. Hydroxycinnamate Conjugates as Potential Monolignol Replacements: In vitro Lignification and Cell Wall Studies with Rosmarinic Acid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yuki, Tobimatsu; Sasikumar, Elumalai; Grabber, John H.

    2012-04-01

    The plasticity of lignin biosynthesis should permit the inclusion of new compatible phenolic monomers, such as rosmarinic acid (RA) and analogous catechol derivatives, into cell-wall lignins that are consequently less recalcitrant to biomass processing. In vitro lignin polymerization experiments revealed that RA readily underwent peroxidase-catalyzed copolymerization with monolignols and lignin oligomers to form polymers with new benzodioxane inter-unit linkages. Incorporation of RA permitted extensive depolymerization of synthetic lignins by mild alkaline hydrolysis, presumably by cleavage of ester intra-unit linkages within RA. Copolymerization of RA with monolignols into maize cell walls by in situ peroxidases significantly enhanced alkaline lignin extractability andmore » promoted subsequent cell wall saccharification by fungal enzymes. Incorporating RA also improved cell wall saccharification by fungal enzymes and by rumen microflora even without alkaline pretreatments, possibly by modulating lignin hydrophobicity and/or limiting cell wall cross-linking. Consequently, we anticipate that bioengineering approaches for partial monolignol substitution with RA and analogous plant hydroxycinnamates would permit more efficient utilization of plant fiber for biofuels or livestock production.« less

  8. Investigation of the Relationship between Illogical Thoughts and Dependence on Others and Marriage Compatibility in the Iranian Veterans Exposed to Chemicals in Iran-Iraq War

    PubMed Central

    Afkar, A. H.; Mahboubi, M.; Shahri, M. Neyakan; Mohamadi, M.; Jalilian, F.; Moradi, F.

    2014-01-01

    Background: Marital satisfaction is one of the main determinants of a family’s correct function. A large number of veterans have been reported to suffer from depression, anxiety, mood disorders, post-traumatic stress disorder, and physical disorders. The objective of this study is to examine association between Illogical thoughts and Dependence on Others and Marriage Compatibility in the Iranian Veterans Exposed to Chemicals in Iran-Iraq War. Methods: The present cross-sectional, analytical study was conducted on 200 veterans exposed to chemicals who were covered by the Foundation of Martyrs and Veterans Affairs, Gilangharb, Kermanshah, Iran. The study sample size was determined according to Krejcie and Morgan formula and the subjects were selected through random sampling. The study data were collected using marriage compatibility questionnaire, illogical thoughts questionnaire, and dependence on others questionnaire. The study data were analyzed using the SPSS statistical software (version18). Pearson correlation coefficient, multiple regression, and t-test were used in order to determine the relationships among the variables and compare the means. Results: The findings of the current study revealed no significant relationship between dependence on others, anxious attention, helplessness, avoiding problems, perfectionism, and autonomy and marriage compatibility. However, a significant relationship was found between failure and marriage compatibility. Discussion: Overall, the findings of the present study showed that the veterans of Gilangharb did not have disorders, but depended on others, particularly their spouses, due to their abnormal physical status. Sometimes, they cannot even do their personal tasks which results in their dependence on others eventually putting the veterans under pressure and stress. PMID:25168982

  9. Chemical compatibility of cartridge materials

    NASA Technical Reports Server (NTRS)

    Wilcox, Roy C.; Zee, R. H.

    1991-01-01

    This twelve month progress report deals with the chemical compatibility of semiconductor crystals grown in zero gravity. Specifically, it studies the chemical compatibility between TZM, a molybdenum alloy containing titanium and zirconium, and WC 103, a titanium alloy containing Niobium and Hafnium, and Gallium arsenide (GaAs) and Cadmium Zinc Tellurite (CdZnTe). Due to the health hazards involved, three approaches were used to study the chemical compatibility between the semiconductor and cartridge materials: reaction retort, thermogravimetric analysis, and bulk cylindrical cartridge containers. A scanning electron microscope with an energy dispersive X-ray analyzer was used to examine all samples after testing. The first conclusion drawn is that reaction rates with TZM were not nearly as great as they were with WC 103. Second, the total reaction between GaAs and WC 103 was almost twice that with TZM. Therefore, even though WC 103 is easier to fabricate, at least half of the cartridge thickness will be degraded if contact is made with one of the semiconductor materials leading to a loss of strength properties.

  10. Novel multi-day sputum transport reagent works with routine tuberculosis tests and eliminates need for cold chain: Preliminary study of compatibility with the Xpert® MTB/RIF assay.

    PubMed

    Kelly-Cirino, Cassandra D; Curry, Patricia S; Marola, Jamie L; Helstrom, Niels K; Salfinger, Max

    2016-11-01

    OMNIgene®•SPUTUM (OM-S) is a sputum transport reagent designed to work with all tuberculosis diagnostics and eliminate the need for cold chain. The aim of this preliminary study was to assess the compatibility of OM-S-treated sputum with the Xpert® MTB/RIF assay. Fifty-five characterized sputa from the FIND TB Specimen Bank were used. Compatibility of OM-S was assessed for both Xpert sample preparation methods: H.1 protocol (sediment, n=25) and H.2 protocol (direct expectorate, n=30). All controls were prepared using the H.2 protocol. Results revealed 100% concordance of MTB/RIF results for all except the low-positive group in the H.1 study arm (n=10; 88% concordance). OM-S-treated sputa were successful in both protocols; if the Xpert buffer is not added during the H.2 procedure, sample viscosity may require repeat testing. Using OM-S could offer users flexibility in clinical testing algorithms. Larger compatibility studies are warranted, particularly with respect to MTB/RIF results for low-positive samples. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Innate factors causing differences in gene flow frequency from transgenic rice to different weedy rice biotypes.

    PubMed

    Zuo, Jiao; Zhang, Lianju; Song, Xiaoling; Dai, Weimin; Qiang, Sheng

    2011-06-01

    The compatibility and outcrossing rates between transgenic rice and weedy rice biotypes have been studied in some previous cases. However, few studies have addressed the reasons for these differences. The present study compared the compatibility and outcrossing rates between transgenic rice and selected weedy rice biotypes using manual and natural crossing experiments to elucidate the key innate factors causing the different outcrossing rates. Hybrid seed sets from manual crossing between transgenic rice and weedy rice varied from 31.8 to 82.7%, which correlated directly with genetic compatibility. Moreover, the significant differences in the quantity of germinated donor pollens and pollen tubes entering the weedy rice ovule directly contributed to the different seed sets. The natural outcrossing rates varied from 0 to 6.66‰. The duration of flowering overlap was the key factor influencing natural outcrossing. Plant and panicle height also affected outcrossing success. From this study, it is concluded that the likelihood of gene flow between transgenic rice and weedy rice biotypes is primarily determined by floral synchronisation and secondarily influenced by genetic compatibility and some morphological characteristics. Copyright © 2011 Society of Chemical Industry.

  12. Invasive candidiasis and oral manifestations in premature newborns

    PubMed Central

    Tinoco-Araujo, José Endrigo; Araújo, Diana Ferreira Gadelha; Barbosa, Patrícia Gomes; Santos, Paulo Sérgio da Silva; de Medeiros, Ana Myriam Costa

    2013-01-01

    ABSTRACT Objective: To investigate prevalence of invasive candidiasis in a Neonatal Intensive Care Unit and to evaluate oral diseases and Candida spp. colonization in low birth weight preterm newborns. Methods: A descriptive epidemiological study performed in two stages. First, prevalence of candidiasis was analyzed in a database of 295 preterm patients admitted to hospital for over 10 days and birth weight less than 2,000g. In the second stage, oral changes and Candida spp. colonization were assessed in 65 patients weighing less than 2,000g, up to 4 week-old, hospitalized for over 10 days and presenting oral abnormalities compatible with fungal lesions. Swab samples were collected in the mouth to identify fungi. Results: Prevalence of candidiasis was 5.4% in the database analyzed. It correlated with prolonged hospital length of stay (p<0.001), in average, 31 days, and 85% risk of developing infection in the first 25 days. It correlated with low birth weight (p<0.001), with mean of 1,140g. The most frequent alterations were white soft plaques, detachable, in oral mucosa and tongue. Intense oral colonization by Candida spp was observed (80%). Conclusions: The frequency of invasive candidiasis was low and correlated with low birth weight and prolonged hospital stay. The most common oral changes were white plaques compatible with pseudomembranous candidiasis and colonization by Candida spp. was above average. PMID:23579747

  13. Modern wireless telecommunication technologies and their electromagnetic compatibility with life-supporting equipment.

    PubMed

    Wallin, Mats K E B; Marve, Therese; Hakansson, Peter K

    2005-11-01

    Hospitals rely on pagers and ordinary telephones to reach staff members in emergency situations. New telecommunication technologies such as General Packet Radio Service (GPRS), the third generation mobile phone system Universal Mobile Telecommunications System (UMTS), and Wireless Local Area Network (WLAN) might be able to replace hospital pagers if they are electromagnetically compatible with medical devices. In this study, we sought to determine if GPRS, UMTS (Wideband Code Division Multiple Access-Frequency Division Duplex [WCDMA FDD]), and WLAN (IEEE 802.11b) transmitted signals interfere with life-supporting equipment in the intensive care and operating room environment. According to United States standard, ANSI C63.18-1997, laboratory tests were performed on 76 medical devices. In addition, clinical tests during 11 operations and 100 h of intensive care were performed. UMTS and WLAN signals caused little interference. Devices using these technologies can be used safely in critical care areas and during operations, but direct contact between medical devices and wireless communication devices ought to be avoided. In the case of GPRS, at a distance of 50 cm, it caused an older infusion pump to alarm and stop infusing; the pump had to be reset. Also, 10 cases of interference with device displays occurred. GPRS can be used safely at a distance of 1 m. Terminals/cellular phones using these technologies should be allowed without restriction in public areas because the risk of interference is minimal.

  14. Standardized 3D Bioprinting of Soft Tissue Models with Human Primary Cells.

    PubMed

    Rimann, Markus; Bono, Epifania; Annaheim, Helene; Bleisch, Matthias; Graf-Hausner, Ursula

    2016-08-01

    Cells grown in 3D are more physiologically relevant than cells cultured in 2D. To use 3D models in substance testing and regenerative medicine, reproducibility and standardization are important. Bioprinting offers not only automated standardizable processes but also the production of complex tissue-like structures in an additive manner. We developed an all-in-one bioprinting solution to produce soft tissue models. The holistic approach included (1) a bioprinter in a sterile environment, (2) a light-induced bioink polymerization unit, (3) a user-friendly software, (4) the capability to print in standard labware for high-throughput screening, (5) cell-compatible inkjet-based printheads, (6) a cell-compatible ready-to-use BioInk, and (7) standard operating procedures. In a proof-of-concept study, skin as a reference soft tissue model was printed. To produce dermal equivalents, primary human dermal fibroblasts were printed in alternating layers with BioInk and cultured for up to 7 weeks. During long-term cultures, the models were remodeled and fully populated with viable and spreaded fibroblasts. Primary human dermal keratinocytes were seeded on top of dermal equivalents, and epidermis-like structures were formed as verified with hematoxylin and eosin staining and immunostaining. However, a fully stratified epidermis was not achieved. Nevertheless, this is one of the first reports of an integrative bioprinting strategy for industrial routine application. © 2015 Society for Laboratory Automation and Screening.

  15. Study on miss distance based on projectile shock wave sensor

    NASA Astrophysics Data System (ADS)

    Gu, Guohua; Cheng, Gang; Zhang, Chenjun; Zhou, Lei

    2017-05-01

    The paper establishes miss distance models based on physical characteristic of shock-wave. The aerodynamic theory shows that the shock-wave of flying super-sonic projectile is generated for the projectile compressing and expending its ambient atmosphere. It advances getting miss distance according to interval of the first sensors, which first catches shock-wave, to solve the problem such as noise filtering on severe background, and signals of amplifier vibration dynamic disposal and electromagnetism compatibility, in order to improves the precision and reliability of gathering wave N signals. For the first time, it can identify the kinds of pills and firing units automatically, measure miss distance and azimuth when pills are firing. Application shows that the tactics and technique index is advanced all of the world.

  16. Biochemistry of whole blood in poly(ethylene-co-ethylacrylate) experimental blood containers.

    PubMed

    Horowitz, B; Rowe, A W; Stryker, M H; Van der Sande, J; Waldman, A A; Wong, S C; Gass, J D; Woods, K R

    1985-01-01

    The biochemical status of whole blood stored in containers fabricated of ethylene ethylacrylate (EEA) film was monitored at several times during 4 weeks of storage at 4 degrees C. Fifteen biochemical indicators were studied to reflect on erythrocyte integrity, cellular metabolism, plasma protein stability, and microaggregate formation. Comparison to storage in polyvinyl chloride (PVC) containers was made by distributing aliquots from each unit of blood among the containers being compared. Whole blood in EEA developed significantly higher levels of plasma hemoglobin, erythrocyte osmotic fragility, and D-glycerate-2,3-diphosphate (2,3-DPG), and somewhat greater glucose utilization, lactate production, and pH. These biochemical differences were not of great magnitude and the data suggest that EEA containers are compatible with the storage of whole blood.

  17. A facet approach to extending the normative component of the theory of reasoned action.

    PubMed

    Donald, I; Cooper, S R

    2001-12-01

    Using facet theory, this study addresses the weak explanatory power of normative influence in theories of reasoned action or planned behaviour. A broad normative construct is hypothesized as being characterized by two facets--social unit and behavioural modality--each of which is examined in relation to recreational drug use. A questionnaire was developed from the facets and administered to undergraduate students. Data (N = 181) were analysed using Smallest Space Analysis (SSA). The results suggest that the facets provide an adequate description of the normative construct and that personal and social normative beliefs, behavioural norms and behavioural intentions can be distinguished empirically. The results also lend partial support to Ajzen's (1988; Ajzen & Fishbein, 1977) principle of compatibility. Implications for how social influence is operationalized and conceptualized are also discussed.

  18. KSC-2013-3560

    NASA Image and Video Library

    2013-09-11

    CAPE CANAVERAL, Fla. – At NASA's Kennedy Space Center in Florida, engineers are running tests between the Mars Atmosphere and Volatile Evolution, or MAVEN, spacecraft and MIL-71. The control room is the Kennedy interface with the Deep Space Network, or DSN. This compatibility test with MAVEN will verify that the spacecraft will be able to relay data back through the DSN interfaces during its mission to the Red Planet. MAVEN is being prepared for its scheduled launch in November from Cape Canaveral Air Force Station, Fla. atop a United Launch Alliance Atlas V rocket. Positioned in an orbit above the Red Planet, MAVEN will study the upper atmosphere of Mars in unprecedented detail. For more information, visit: http://www.nasa.gov/mission_pages/maven/main/index.html Photo credit: NASA/Jim Grossmann

  19. Compatible poliomyelitis cases in India during 2000.

    PubMed Central

    Kohler, Kathryn A.; Hlady, W. Gary; Banerjee, Kaushik; Gupta, Dhananjoy; Francis, Paul; Durrani, Sunita; Zuber, Patrick L. F.; Sutter, Roland W.

    2003-01-01

    OBJECTIVE: To describe the characteristics of compatible poliomyelitis cases and to assess the programmatic implications of clusters of such cases in India. METHODS: We described the characteristics of compatible poliomyelitis cases, identified clusters of compatible cases (two or more in the same district or neighbouring districts within two months), and examined their relationship to wild poliovirus cases. FINDINGS: There were 362 compatible cases in 2000. The incidence of compatible cases was higher in districts with laboratory-confirmed poliomyelitis cases than in districts without laboratory-confirmed cases. Of 580 districts, 96 reported one compatible case and 72 reported two or more compatible cases. Among these 168 districts with at least one compatible case, 123 had internal or cross- border clusters of compatible cases. In 27 districts with clusters of compatible cases, no wild poliovirus was isolated either in the same district or in neighbouring districts. Three of these 27 districts presented laboratory-confirmed poliomyelitis cases during 2001. CONCLUSION: Most clusters of compatible cases occurred in districts identified as areas with continuing wild poliovirus transmission and where mopping-up vaccination campaigns were carried out. As certification nears, areas with compatible poliomyelitis cases should be investigated and deficiencies in surveillance should be corrected in order to ensure that certification is justified. PMID:12640469

  20. Design and evaluation of an innovative MRI-compatible Braille stimulator with high spatial and temporal resolution.

    PubMed

    Debowska, Weronika; Wolak, Tomasz; Soluch, Pawel; Orzechowski, Mateusz; Kossut, Malgorzata

    2013-02-15

    Neural correlates of Braille reading have been widely studied with different neuroimaging techniques. Nevertheless, the exact brain processes underlying this unique activity are still unknown, due to suboptimal accuracy of imaging and/or stimuli delivery methods. To study somatosensory perception effectively, the stimulation must reflect parameters of the natural stimulus and must be applied with precise timing. In functional magnetic resonance imaging (fMRI) providing these characteristics requires technologically advanced solutions and there have been several successful direct tactile stimulation devices designed that allow investigation of somatotopic organization of brain sensory areas. They may, however, be of limited applicability in studying brain mechanisms related to such distinctive tactile activity as Braille reading. In this paper we describe the design and experimental evaluation of an innovative MRI-compatible Braille Character Stimulator (BCS) enabling precise and stable delivery of standardized Braille characters with high temporal resolution. Our device is fully programmable, flexible in stimuli delivery and can be easily implemented in any research unit. The Braille Character Stimulator was tested with a same-different discrimination task on Braille characters during an event-related fMRI experiment in eleven right-handed sighted adult subjects. The results show significant activations in several cortical areas, including bilateral primary (SI) and secondary somatosensory (SII) cortices, bilateral premotor and supplementary motor areas, inferior frontal gyri, inferior temporal gyri and precuneus, as well as contralateral (to the stimulated hand) thalamus. The results validate the use of the BCS as a method of effective stimuli application in fMRI studies, in both sighted and visually impaired subjects. Copyright © 2012 Elsevier B.V. All rights reserved.

  1. Flexible carbon micro-supercapacitors prepared by direct cw-laser writing

    NASA Astrophysics Data System (ADS)

    Cai, Jinguang; Watanabe, Akira

    2016-03-01

    Micro-/nano-scale power supply units with high energy and high power densities are critical components for the development of compact miniaturized portable electronic devices. Supercapacitors have attracted many research attentions due to their high power density, robust cycle performance, pollution-free operation, and maintenance-free features. Besides, the properties of small size, light weight, and flexibility are also required. On-chip microsupercapacitors (MSCs) have the potential acting as power supply units in portable devices, due to their simplified packaging processes and compatibility to the integrated circuits. However, the fabrication methods and materials should be cost-effective, scalable, and compatible to current electronic industry. Carbon materials own high specific surface areas, electrochemical stability, and high electrical conductivity, which are critical parameters for high-power supercapacitors. Moreover, the high mechanical tolerance makes them good candidates for flexible wearable devices. Therefore, MSCs based on carbon materials would satisfy the requirements of portable electronics. In this work, we demonstrated the fabrication of carbon MSCs by laser direct writing on commercial polyimide sheets in Ar with lowcost semiconductor cw-laser with a wavelength of 405nm. The obtained structures are macro-nanostructures comprising graphitized and amorphous carbon with relatively smooth surfaces and low resistance, in compared with the structures obtained by laser writing in air. As-prepared micro-supercapacitors show a high capacitance of about 14.9 mF/cm2 at a scanning rate of 10 mV/s, which is comparable to the reported highest capacitance of carbon-based supercapacitors fabricated by pulse-laser writing.

  2. The effects of innovation factors on smartphone adoption among nurses in community hospitals.

    PubMed

    Putzer, Gavin J; Park, Yangil

    2010-01-01

    A relatively new mobile technological device is the smartphone-a phone with advanced features such as Windows Mobile software, access to the Internet, and other computer processing capabilities. This article investigates the decision to adopt a smartphone among healthcare professionals, specifically nurses. The study examines constructs that affect an individual's decision to adopt a smartphone by employing innovation attributes leading to perceived attitudes. We hypothesize that individual intentions to use a smartphone are mostly determined by attitudes toward using a smartphone, which in turn are affected by innovation characteristics. Innovation characteristics are factors that help explain whether a user will adopt a new technology. The study consisted of a survey disseminated to 200 practicing nurses selected from two community hospitals in the southeastern United States. In our model, the innovation characteristics of observability, compatibility, job relevance, internal environment, and external environment were significant predictors of attitude toward using a smartphone.

  3. Shuttle user analysis (study 2.2): Volume 3. Business Risk And Value of Operations in space (BRAVO). Part 4: Computer programs and data look-up

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Computer program listings as well as graphical and tabulated data needed by the analyst to perform a BRAVO analysis were examined. Graphical aid which can be used to determine the earth coverage of satellites in synchronous equatorial orbits was described. A listing for satellite synthesis computer program as well as a sample printout for the DSCS-11 satellite program and a listing of the symbols used in the program were included. The APL language listing for the payload program cost estimating computer program was given. This language is compatible with many of the time sharing remote terminals computers used in the United States. Data on the intelsat communications network was studied. Costs for telecommunications systems leasing, line of sight microwave relay communications systems, submarine telephone cables, and terrestrial power generation systems were also described.

  4. Looking back in time: self-concept change affects visual perspective in autobiographical memory.

    PubMed

    Libby, Lisa K; Eibach, Richard P

    2002-02-01

    People who change often report that their old selves seem like "different people." Correlational (Study 1) and experimental (Studies 2 and 3) studies showed that participants tended to use a 3rd-person observer perspective when visualizing memories of actions that conflicted with their current self-concept. A similar pattern emerged when participants imagined performing actions that varied in self-concept compatibility (Study 4). The authors conclude that on-line judgments of an action's self-concept compatibility affect the perspective used for image construction. Study 5 shows applied implications. Use of the 3rd-person perspective when recalling past episodes of overindulgent eating was related to optimism about behaving differently at an upcoming Thanksgiving dinner. The authors discuss the effect of self-concept compatibility on cognitive and emotional reactions to past actions and consider the role of causal attributions in defining the self across time.

  5. Compatibility of the insect pathogenic fungus Beauveria bassiana with neem against sweetpotato whitefly, Bemisia tabaci, on eggplant

    USDA-ARS?s Scientific Manuscript database

    A study on the compatibility of the entomopathogenic fungus Beauveria bassiana (Balsamo) Vuillemin (Ascomycota: Hypocreales) with neem was conducted against sweetpotato whitefly, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae), on eggplant. Initially, three concentrations of B. bassiana (106, 1...

  6. Role Specific Pupil/Science Teacher Interpersonal Compatibility and Science Attitudes.

    ERIC Educational Resources Information Center

    Vargo, Robert A.; Schafer, Larry E.

    As science teaching becomes more inquiry oriented, science teachers are interacting more frequently with individual students. With increased interaction, pupil/science teacher interpersonal compatibility most likely contributes significantly to the development of students' science attitudes. The purpose of the present study was to examine the…

  7. Oral manifestations compatible with chronic graft-versus-host disease in patients with Fanconi anemia.

    PubMed

    Grein Cavalcanti, Laura; Fuentes Araújo, Renata L; Bonfim, Carmem; Torres-Pereira, Cassius C

    2015-02-01

    Fanconi anemia (FA) is a genetic disease that is characterized by several congenital abnormalities and progressive bone marrow failure and is associated with an increased susceptibility to malignant disorders. Currently, the only potential cure for hematological disorders is hematopoietic stem cell transplantation (HSCT). However, 1 of the most common complications after HSCT is the development of oral chronic graft-versus-host disease (cGVHD), which is also a risk factor for the development of cancer, particularly oral squamous cell carcinoma. Therefore, the purpose of this study was to describe the prevalence and characteristics of oral manifestations compatible with cGVHD in patients diagnosed with FA according to the National Institutes of Health (NIH) consensus criteria. A total of 96 patients (51 females, 45 males; median age, 16 years) with FA, who were in medical follow-up after HSCT at the outpatient clinic of the bone marrow transplantation unit (Hospital de Clínicas from the Universidade Federal do Paraná) underwent an oral evaluation between January 2013 and December 2013. Post-HSCT periods varied from 1 to 261 months and were divided into 3 periods: immediate post-HSCT period; intermediate post-HSC period, and late post-HSCT period. Among the evaluated patients, 40 of 96 (42%) presented with oral manifestations of cGVHD, with 29 of 40 (73%) of these patients in the late post-HSCT period. NIH scale scores varied from 0 to 10, and lichenoid and hyperkeratotic lesions were the abnormalities most frequently observed (100%). Overall, a high prevalence of oral manifestations was observed for cGVHD patients with FA. These data highlight the importance of monitoring oral manifestations compatible with cGVHD to identify and treat individuals with a higher risk of developing oral cancer. Copyright © 2015 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

  8. The influence of the Japanese waving cat on the joint spatial compatibility effect: A replication and extension of Dolk, Hommel, Prinz, and Liepelt (2013).

    PubMed

    Puffe, Lydia; Dittrich, Kerstin; Klauer, Karl Christoph

    2017-01-01

    In a joint go/no-go Simon task, each of two participants is to respond to one of two non-spatial stimulus features by means of a spatially lateralized response. Stimulus position varies horizontally and responses are faster and more accurate when response side and stimulus position match (compatible trial) than when they mismatch (incompatible trial), defining the social Simon effect or joint spatial compatibility effect. This effect was originally explained in terms of action/task co-representation, assuming that the co-actor's action is automatically co-represented. Recent research by Dolk, Hommel, Prinz, and Liepelt (2013) challenged this account by demonstrating joint spatial compatibility effects in a task-setting in which non-social objects like a Japanese waving cat were present, but no real co-actor. They postulated that every sufficiently salient object induces joint spatial compatibility effects. However, what makes an object sufficiently salient is so far not well defined. To scrutinize this open question, the current study manipulated auditory and/or visual attention-attracting cues of a Japanese waving cat within an auditory (Experiment 1) and a visual joint go/no-go Simon task (Experiment 2). Results revealed that joint spatial compatibility effects only occurred in an auditory Simon task when the cat provided auditory cues while no joint spatial compatibility effects were found in a visual Simon task. This demonstrates that it is not the sufficiently salient object alone that leads to joint spatial compatibility effects but instead, a complex interaction between features of the object and the stimulus material of the joint go/no-go Simon task.

  9. Single unit approaches to human vision and memory.

    PubMed

    Kreiman, Gabriel

    2007-08-01

    Research on the visual system focuses on using electrophysiology, pharmacology and other invasive tools in animal models. Non-invasive tools such as scalp electroencephalography and imaging allow examining humans but show a much lower spatial and/or temporal resolution. Under special clinical conditions, it is possible to monitor single-unit activity in humans when invasive procedures are required due to particular pathological conditions including epilepsy and Parkinson's disease. We review our knowledge about the visual system and visual memories in the human brain at the single neuron level. The properties of the human brain seem to be broadly compatible with the knowledge derived from animal models. The possibility of examining high-resolution brain activity in conscious human subjects allows investigators to ask novel questions that are challenging to address in animal models.

  10. Lack of thyroid hormone effect on activation energy of NaK-ATPase.

    PubMed

    Rahimifar, M; Ismail-Beigi

    1977-02-01

    In order to differentiate whether activation of NaK-ATPase in thyroid thermogenesis is due to increased numbers of active 'sodium pump' units or due to a change in the kinetics of the enzyme, the effect of T3 on activation energy (Ea) of NaK-ATPase was determined in rat liver, kidney and brain. Injection of T3 produced significant increases in the specific activity of NaK-ATPase in liver and kidney but not in brain homogenates. T3 injections produced no significant change in the Ea of NaK-ATPase in any of the three tissues. The data are compatible with the hypothesis that thyroid stimulation of the sodium pump is brought about by an increase in the number of active pump units.

  11. Electric prototype power processor for a 30cm ion thruster

    NASA Technical Reports Server (NTRS)

    Biess, J. J.; Inouye, L. Y.; Schoenfeld, A. D.

    1977-01-01

    An electrical prototype power processor unit was designed, fabricated and tested with a 30 cm mercury ion engine for primary space propulsion. The power processor unit used the thyristor series resonant inverter as the basic power stage for the high power beam and discharge supplies. A transistorized series resonant inverter processed the remaining power for the low power outputs. The power processor included a digital interface unit to process all input commands and internal telemetry signals so that electric propulsion systems could be operated with a central computer system. The electrical prototype unit included design improvement in the power components such as thyristors, transistors, filters and resonant capacitors, and power transformers and inductors in order to reduce component weight, to minimize losses, and to control the component temperature rise. A design analysis for the electrical prototype is also presented on the component weight, losses, part count and reliability estimate. The electrical prototype was tested in a thermal vacuum environment. Integration tests were performed with a 30 cm ion engine and demonstrated operational compatibility. Electromagnetic interference data was also recorded on the design to provide information for spacecraft integration.

  12. Auxiliary propulsion system flight package

    NASA Technical Reports Server (NTRS)

    Collett, C. R.

    1987-01-01

    Hughes Aircraft Company developed qualified and integrated flight, a flight test Ion Auxiliary Propulsion System (IAPS), on an Air Force technology satellite. The IAPS Flight Package consists of two identical Thruster Subsystems and a Diagnostic Subsystem. Each thruster subsystem (TSS) is comprised of an 8-cm ion Thruster-Gimbal-Beam Shield Unit (TGBSU); Power Electronics Unit; Digital Controller and Interface Unit (DCIU); and Propellant Tank, Valve and Feed Unit (PTVFU) plus the requisite cables. The Diagnostic Subsystem (DSS) includes four types of sensors for measuring the effect of the ion thrusters on the spacecraft and the surrounding plasma. Flight qualifications of IAPS, prior to installation on the spacecraft, consisted of performance, vibration and thermal-vacuum testing at the unit level, and thermal-vacuum testing at the subsystem level. Mutual compatibility between IAPS and the host spacecraft was demonstrated during a series of performance and environmental tests after the IAPS Flight Package was installed on the spacecraft. After a spacecraft acoustic test, performance of the ion thrusters was reverified by removing the TGBSUs for a thorough performance test at Hughes Research Laboratories (HRL). The TGBSUs were then reinstalled on the spacecraft. The IAPS Flight Package is ready for flight testing when Shuttle flights are resumed.

  13. Isometric contractions of motor units in a fast twitch muscle of the cat

    PubMed Central

    Bagust, J.; Knott, Sarah; Lewis, D. M.; Luck, J. C.; Westerman, R. A.

    1973-01-01

    1. Isosmetric contractions of cat flexor digitorum longus whole muscles and of functionally isolated motor units have been measured under conditions similar to those used by Buller & Lewis (1965a). 2. Motor unit twitch time to peak was inversely related to axonal conduction velocity. The logarithm of tetanic tension was directly related to conduction velocity. These relationships suggest that each motoneurone has an influence on the muscle fibres which it innervates. 3. The ratio of twitch to tetanic tension was directly related to the time to peak of the motor unit. This fact might be explained by variation between motor units of the duration of `active state'. 4. The muscle length at which tension was maximal varied between motor units and the optima were found over the range of muscle lengths which could occur in the body. Slow motor units had longer optimal lengths. 5. The sample of motor units was considered to be unbiased because the distribution of axon conduction velocities was compatible with reported motor fibre diameter spectra of the muscle nerve. The mean motor unit tetanic tension gave a reasonable estimate of the number of α-motor axons in the muscle nerve. Twitch tensions gave a value that was 40% higher. 6. Motor unit and whole muscle data were in good agreement for length-tetanus tension curves, for times to peak and for twitch-tetanus ratios at long muscle lengths. PMID:4715372

  14. Is group A thawed plasma suitable as the first option for emergency release transfusion? (CME).

    PubMed

    Chhibber, Vishesh; Greene, Mindy; Vauthrin, Michelle; Bailey, Jeff; Weinstein, Robert

    2014-07-01

    Group AB plasma, which lacks anti-A and anti-B isohemagglutinins, is issued for emergency transfusion when a patient's ABO group is unknown, but the relative scarcity of group AB blood donors limits its availability. We sought to establish a thawed plasma inventory to improve the rapid availability of plasma in the emergency release setting but were concerned about potential wastage of group AB plasma. Recognizing that plasma-incompatible apheresis platelets are routinely transfused and only rarely result in hemolytic reactions if the donor is blood group O, and considering that group A plasma would be compatible with approximately 85% of our patient population, we instituted an emergency release policy whereby thawed group A plasma is issued to all patients of unknown blood group or if compatible plasma is not available. ABO-compatible plasma is then issued, if needed, once the patient's blood group is determined. We prospectively assessed the outcomes of all patients who received incompatible plasma under our policy. During the first 5 years under this policy, 385 emergency release requests for plasma were received by our blood bank. Among them, 23 group B or AB patients met criteria for receiving a median of 2 units of incompatible group A plasma. No hemolytic transfusion reactions or other adverse events related to transfusion were seen in any of these 23 patients. We propose that group A plasma may be an acceptable alternative to AB plasma as the first option in the emergency release setting. © 2014 AABB.

  15. Plant-like mating in an animal: sexual compatibility and allocation trade-offs in a simultaneous hermaphrodite with remote transfer of sperm.

    PubMed

    Pemberton, A J; Sommerfeldt, A D; Wood, C A; Flint, H C; Noble, L R; Clarke, K R; Bishop, J D D

    2004-05-01

    The importance of sexual compatibility between mates has only recently been realized in zoological research into sexual selection, yet its study has been central to botanical research for many decades. The reproductive characteristics of remote mating, an absence of precopulatory mate screening, internal fertilization and embryonic brooding are shared between passively pollinated plants and a phylogenetically diverse group of sessile aquatic invertebrates. Here, we further characterize the sexual compatibility system of one such invertebrate, the colonial ascidian Diplosoma listerianum. All 66 reciprocal pairings of 12 genetic individuals were carried out. Fecundities of crosses varied widely and suggested a continuous scale of sexual compatibility. Of the 11 animals from the same population c. 40% of crosses were completely incompatible with a further c. 20% having obvious partial compatibility (reduced fecundity). We are unaware of other studies documenting such high levels of sexual incompatibility in unrelated individuals. RAPD fingerprinting was used to estimate relatedness among the 12 individuals after a known pedigree was successfully reconstructed to validate the technique. In contrast to previous results, no correlation between genetic similarity and sexual compatibility was detected. The blocking of many genotypes of sperm is expected to severely modify realized paternity away from 'fair raffle' expectations and probably reduce levels of intra-brood genetic diversity in this obligatorily promiscuous mating system. One adaptive benefit may be to reduce the bombardment of the female reproductive system by outcrossed sperm with conflicting evolutionary interests, so as to maintain female control of somatic : gametic investment.

  16. Torrefaction Processing for Human Solid Waste Management

    NASA Technical Reports Server (NTRS)

    Serio, Michael A.; Cosgrove, Joseph E.; Wójtowicz, Marek A.; Stapleton, Thomas J.; Nalette, Tim A.; Ewert, Michael K.; Lee, Jeffrey; Fisher, John

    2016-01-01

    This study involved a torrefaction (mild pyrolysis) processing approach that could be used to sterilize feces and produce a stable, odor-free solid product that can be stored or recycled, and also to simultaneously recover moisture. It was demonstrated that mild heating (200-250 C) in nitrogen or air was adequate for torrefaction of a fecal simulant and an analog of human solid waste (canine feces). The net result was a nearly undetectable odor (for the canine feces), complete recovery of moisture, some additional water production, a modest reduction of the dry solid mass, and the production of small amounts of gas and liquid. The liquid product is mainly water, with a small Total Organic Carbon content. The amount of solid vs gas plus liquid products can be controlled by adjusting the torrefaction conditions (final temperature, holding time), and the current work has shown that the benefits of torrefaction could be achieved in a low temperature range (< 250 C). These temperatures are compatible with the PTFE bag materials historically used by NASA for fecal waste containment and will reduce the energy consumption of the process. The solid product was a dry material that did not support bacterial growth and was hydrophobic relative to the starting material. In the case of canine feces, the solid product was a mechanically friable material that could be easily compacted to a significantly smaller volume (approx. 50%). The proposed Torrefaction Processing Unit (TPU) would be designed to be compatible with the Universal Waste Management System (UWMS), now under development by NASA. A stand-alone TPU could be used to treat the canister from the UWMS, along with other types of wet solid wastes, with either conventional or microwave heating. Over time, a more complete integration of the TPU and the UWMS could be achieved, but will require design changes in both units.

  17. Compatibility and Efficacy of Isaria fumosorosea with Horticultural Oils for Mitigation of the Asian Citrus Psyllid, Diaphorina citri (Hemiptera: Liviidae).

    PubMed

    Kumar, Vivek; Avery, Pasco B; Ahmed, Juthi; Cave, Ronald D; McKenzie, Cindy L; Osborne, Lance S

    2017-10-31

    Horticultural oils are an important component of integrated management programs of several phytophagous arthropods and pathogens affecting fruit, ornamentals and vegetables in greenhouse and field production systems. Although effective against the target pest, their incompatibility with biological control agents can compromise efforts to develop eco-friendly management programs for important agricultural pests. In this study, we assessed the in vitro effect of selected refined petroleum oils used in citrus and other horticultural crops with a biopesticide containing the entomopathogenic fungi, Isaria fumosorosea (PFR-97) under laboratory conditions. Further, we used leaf disk bioassays to evaluate the combined efficacy of petroleum oils and I. fumosorosea against the Asian citrus psyllid, Diaphorina citri (Hemiptera: Liviidae), a major pest of citrus in the United States. All five petroleum oil treatments (Orchex, Sun Pure, Conoco Blend -1, Conoco Blend -2, and JMS) were compatible with I. fumosorosea blastospores, as none of them were found to affect I. fumosorosea colony-forming units and radial fungal growth measured at 3, 6, 9, and 12 days post-inoculation. All mixed treatments performed better than I. fumosorosea alone against D. citri , where the highest mean survival time of D. citri was 12.5 ± 0.7 days. No significant differences in D. citri survival time and I. fumosorosea growth (fungal development index) on dead cadavers, which is important for determining their horizontal transmission, were observed when mixed with Orchex, Sun Pure, Conoco Blend -2, and JMS. Results indicated that horticultural oils in combination with I. fumosorosea could offer citrus growers an alternative treatment for integrating into their current management programs while battling against D. citri in citrus production systems. Due to their eco-friendly, broad-spectrum effect, it could provide control against various citrus pests, while also encouraging the retention of effective chemistries for a longer period in the marketplace. However promising, these combination treatments need to be tested further with I. fumosorosea under grove conditions to confirm their field efficacy.

  18. The design and evaluation of an antimicrobial resistance surveillance system for neonatal intensive care units in Iran.

    PubMed

    Rezaei-Hachesu, Peyman; Samad-Soltani, Taha; Yaghoubi, Sajad; GhaziSaeedi, Marjan; Mirnia, Kayvan; Masoumi-Asl, Hossein; Safdari, Reza

    2018-07-01

    Neonatal intensive care units (NICUs) have complex patients in terms of their diagnoses and required treatments. Antimicrobial treatment is a common therapy for patients in NICUs. To solve problems pertaining to empirical therapy, antimicrobial stewardship programs have recently been introduced. Despite the success of these programs in terms of data collection, there is still inefficiency in terms of analyzing and reporting the data. Thus, to successfully implement these stewardship programs, the design of antimicrobial resistance (AMR) surveillance systems is recommended as a first step. As a result, this study aimed to design an AMR surveillance system for use in the NICUs in northwestern Iranian hospitals to cover these information gaps. The recommended system is compatible with the World Health Organization (WHO) guidelines. The business intelligence (BI) requirements were extracted in an interview with a product owner (PO) using a valid and reliable checklist. Following this, an AMR surveillance system was designed and evaluated in relation to user experiences via a user experience questionnaire (UEQ). Finally, an association analysis was performed on the database, and the results were reported by identifying the important multidrug resistances in the database. A customized software development methodology was proposed. The three major modules of the AMR surveillance are the data registry, dashboard, and decision support modules. The data registry module was implemented based on a three-tier architecture, and the Clinical Decision Support System (CDSS) and dashboard modules were designed based on the BI requirements of the Scrum product owner (PO). The mean values of UEQ measures were in a good range. This measures showed the suitable usability of the AMR surveillance system. Applying efficient software development methodologies allows for the systems' compatibility with users' opinions and requirements. In addition, the construction of interdisciplinary communication models for research and software engineering allows for research and development concepts to be used in operational environments. Copyright © 2018 Elsevier B.V. All rights reserved.

  19. Anti-Jk3 in a Filipino man.

    PubMed

    McCaskill, Shaina; Wise, Scott; Tinsley, Sheila

    2015-01-01

    A 62-year-old Filipino man with a history of chronic obstructive pulmonary disease, hypertension, and hyperlipidemia was admitted to the emergency department at Hospital A with recurrent fevers, weakness, and jaundice. The patient was evaluated and eventually discharged with a diagnosis of possible drug-induced hepatitis. One month later, the patient was admitted to Hospital B for recurrent fevers and weakness. The patient's hemoglobin was 3.8 g/dL. Six units of packed red blood cells (RBCs) were ordered for transfusion. The patient's sample typed as group B, D+, and the antibody screen was negative. All six units of packed RBCs appeared compatible (at immediate spin) and were transfused to the patient. His hemoglobin level 4 days post-transfusion was 9.3 g/dL, and the patient was discharged. The patient returned after a week for follow-up and his hemoglobin was found to have dropped to 8.5 g/dL, which continued to fall until it reached 7.0 g/dL. Additional packed RBCs were ordered for transfusion. during subsequent pre-transfusion compatibility testing, the antibody screen was found to be positive (all screening cells reactive at the antihuman globulin phase). An antibody identification panel was performed.The patient's serum was found to react with all panel cells tested, including the autocontrol tube. A direct antiglobulin test revealed the presence of both anti-IgG and anti-C3 coating the patient's RBCs. The specimen was then sent to a reference laboratory for further testing. Results from the reference lab testing revealed the presence of anti-Jk3 in the patient's serum. the patient was placed on steroids, and his reticulocyte count increased with no further signs of extravascular hemolysis. No additional transfusions were necessary. he was eventually discharged with a hemoglobin of 13.6 g/dL. the purpose of this case study is to report the findings of an extremely rare but clinically significant antibody, anti-Jk3.

  20. Investigation of Galactic open cluster remnants: the case of NGC 7193

    NASA Astrophysics Data System (ADS)

    de Souza Angelo, Mateus; Francisco Coelho dos Santos, João, Jr.; Barbosa Corradi, Wagner José; Ferreira de Souza Maia, Francisco; Piatti, Andrés Eduardo

    2017-01-01

    Galactic open clusters (OCs) that survive the early gas-expulsion phase are gradually destroyed over time by the action of disruptive dynamical processes. Their final evolutionary stages are characterized by a poorly populated concentration of stars called an open cluster remnant (OCR). This study is devoted to assessing the real physical nature of the OCR candidate NGC 7193. GMOS/Gemini spectroscopy of 53 stars in the inner target region were obtained to derive radial velocities and atmospheric parameters. We also employed photometric and proper motion data. The analysis method consists of the following steps: (i) analysis of the statistical resemblance between the cluster and a set of field samples with respect to the sequences defined in color-magnitude diagrams (CMDs); (ii) a 5-dimensional iterative exclusion routine was employed to identify outliers from kinematical and positional data; (iii) isochrone fitting to the Ks×(J-Ks) CMD of the remaining stars and the dispersion of spectral types along empirical sequences in the (J-H)×(H-Ks) diagram were checked. A group of stars was identified for which the mean heliocentric distance is compatible with that obtained via isochrone fitting and whose metallicities are compatible with each other. Fifteen of the member stars observed spectroscopically were identified together with another 19 probable members. Our results indicate that NGC 7193 is a genuine OCR, of a once very populous OC, for which the following parameters were derived: d = 501±46 pc, t=2.5+/-1.2 Gyr, < [Fe/H] >=-0.17+/-0.23 and E(B-V)=0.05+/-0.05. Its luminosity and mass functions show depletion of low mass stars, confirming the OCR is in a dynamically evolved state. Based on observations obtained at the Gemini Observatory, which is operated by the AURA under a cooperative agreement with the NSF on behalf of the Gemini partnership: NSF (United States), STFC (United Kingdom), NRC (Canada), CONICYT (Chile), ARC (Australia), CNPq (Brazil) and CONICET (Argentina).

  1. Redox dependent behaviour of molybdenum during magmatic processes in the terrestrial and lunar mantle: Implications for the Mo/W of the bulk silicate Moon

    NASA Astrophysics Data System (ADS)

    Leitzke, F. P.; Fonseca, R. O. C.; Sprung, P.; Mallmann, G.; Lagos, M.; Michely, L. T.; Münker, C.

    2017-09-01

    We present results of high-temperature olivine-melt, pyroxene-melt and plagioclase-melt partitioning experiments aimed at investigating the redox transition of Mo in silicate systems. Data for a series of other minor and trace elements (Sc, Ba, Sr, Cr, REE, Y, HFSE, U, Th and W) were also acquired to constrain the incorporation of Mo in silicate minerals. All experiments were carried out in vertical tube furnaces at 1 bar and temperatures ranging from ca. 1220 to 1300 °C. Oxygen fugacity was controlled via CO-CO2 gas mixtures and varied systematically from 5.5 log units below to 1.9 log units above the fayalite-magnetite-quartz (FMQ) redox buffer thereby covering the range in oxygen fugacities of terrestrial and lunar basalt genesis. Molybdenum is shown to be volatile at oxygen fugacities above FMQ and that its compatibility in pyroxene and olivine increases three orders of magnitude towards the more reducing conditions covered in this study. The partitioning results show that Mo is dominantly tetravalent at redox conditions below FMQ-4 and dominantly hexavalent at redox conditions above FMQ. Given the differences in oxidation states of the terrestrial (oxidized) and lunar (reduced) mantles, molybdenum will behave significantly differently during basalt genesis in the Earth (i.e. highly incompatible; average DMoperidotite/melt ∼ 0.008) and Moon (i.e. moderately incompatible/compatible; average DMoperidotite/melt ∼ 0.6). Thus, it is expected that Mo will strongly fractionate from W during partial melting in the lunar mantle, given that W is broadly incompatible at FMQ-5. Moreover, the depletion of Mo and the Mo/W range in lunar samples can be reproduced by simply assuming a primitive Earth-like Mo/W for the bulk silicate Moon. Such a lunar composition is in striking agreement with the Moon being derived from the primitive terrestrial mantle after core formation on Earth.

  2. Examination of the Compatibility of the Questions Used by Social Studies Teachers in the Class with the Program Achievements According to the SOLO Taxonomy

    ERIC Educational Resources Information Center

    Keskin, Yusuf; Keskin, Sevgi C.; Kirtel, Aysegül

    2016-01-01

    The purpose of this study is to examine the compatibility of the questions used by the social studies branch teachers in the level of 6th and 7th grade with the achievements included in the teaching program. Structure of observed learning outcome (SOLO) taxonomy, which was presented by Biggs and Colis (1982) as an alternative to Bloom's cognitive…

  3. The transcriptional regulator, CosR, controls compatible solute biosynthesis and transport, motility and biofilm formation in Vibrio cholerae.

    PubMed

    Shikuma, Nicholas J; Davis, Kimberly R; Fong, Jiunn N C; Yildiz, Fitnat H

    2013-05-01

    Vibrio cholerae inhabits aquatic environments and colonizes the human digestive tract to cause the disease cholera. In these environments, V. cholerae copes with fluctuations in salinity and osmolarity by producing and transporting small, organic, highly soluble molecules called compatible solutes, which counteract extracellular osmotic pressure. Currently, it is unclear how V. cholerae regulates the expression of genes important for the biosynthesis or transport of compatible solutes in response to changing salinity or osmolarity conditions. Through a genome-wide transcriptional analysis of the salinity response of V. cholerae, we identified a transcriptional regulator we name CosR for compatible solute regulator. The expression of cosR is regulated by ionic strength and not osmolarity. A transcriptome analysis of a ΔcosR mutant revealed that CosR represses genes involved in ectoine biosynthesis and compatible solute transport in a salinity-dependent manner. When grown in salinities similar to estuarine environments, CosR activates biofilm formation and represses motility independently of its function as an ectoine regulator. This is the first study to characterize a compatible solute regulator in V. cholerae and couples the regulation of osmotic tolerance with biofilm formation and motility. © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

  4. The imitation game: Effects of social cues on 'imitation' are domain-general in nature.

    PubMed

    Marsh, Lauren E; Bird, Geoffrey; Catmur, Caroline

    2016-10-01

    Imitation has been hailed as 'social glue', facilitating rapport with others. Previous studies suggest that social cues modulate imitation but the mechanism of such modulation remains underspecified. Here we examine the locus, specificity, and neural basis of the social control of imitation. Social cues (group membership and eye gaze) were manipulated during an imitation task in which imitative and spatial compatibility could be measured independently. Participants were faster to perform compatible compared to incompatible movements in both spatial and imitative domains. However, only spatial compatibility was modulated by social cues: an interaction between group membership and eye gaze revealed more spatial compatibility for ingroup members with direct gaze and outgroup members with averted gaze. The fMRI data were consistent with this finding. Regions associated with the control of imitative responding (temporoparietal junction, inferior frontal gyrus) were more active during imitatively incompatible compared to imitatively compatible trials. However, this activity was not modulated by social cues. On the contrary, an interaction between group, gaze and spatial compatibility was found in the dorsolateral prefrontal cortex in a pattern consistent with reaction times. This region may be exerting control over the motor system to modulate response inhibition. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  5. Zwitterionic polymer functionalization of polysulfone membrane with improved antifouling property and blood compatibility by combination of ATRP and click chemistry.

    PubMed

    Xiang, Tao; Lu, Ting; Xie, Yi; Zhao, Wei-Feng; Sun, Shu-Dong; Zhao, Chang-Sheng

    2016-08-01

    The chemical compositions are very important for designing blood-contacting membranes with good antifouling property and blood compatibility. In this study, we propose a method combining ATRP and click chemistry to introduce zwitterionic polymer of poly(sulfobetaine methacrylate) (PSBMA), negatively charged polymers of poly(sodium methacrylate) (PNaMAA) and/or poly(sodium p-styrene sulfonate) (PNaSS), to improve the antifouling property and blood compatibility of polysulfone (PSf) membranes. Attenuated total reflectance-Fourier transform infrared spectra, X-ray photoelectron spectroscopy and water contact angle results confirmed the successful grafting of the functional polymers. The antifouling property and blood compatibility of the modified membranes were systematically investigated. The zwitterionic polymer (PSBMA) grafted membranes showed good resistance to protein adsorption and bacterial adhesion; the negatively charged polymer (PNaSS or PNaMAA) grafted membranes showed improved blood compatibility, especially the anticoagulant property. Moreover, the PSBMA/PNaMAA modified membrane showed both antifouling property and anticoagulant property, and exhibited a synergistic effect in inhibiting blood coagulation. The functionalization of membrane surfaces by a combination of ATRP and click chemistry is demonstrated as an effective route to improve the antifouling property and blood compatibility of membranes in blood-contact. Copyright © 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  6. Operation Compatibility: A Neglected Contribution to Dual-Task Costs

    ERIC Educational Resources Information Center

    Pannebakker, Merel M.; Band, Guido P. H.; Ridderinkhof, K. Richard

    2009-01-01

    Traditionally, dual-task interference has been attributed to the consequences of task load exceeding capacity limitations. However, the current study demonstrates that in addition to task load, the mutual compatibility of the concurrent processes modulates whether 2 tasks can be performed in parallel. In 2 psychological refractory period…

  7. 78 FR 30385 - Approval of Noise Compatibility Program for Tweed-New Haven Regional Airport

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... use of flight procedures can be implemented within the period covered by the program without... maps, descriptions, and other documentation produced during the noise compatibility planning study... 180 days (other than the use of new flight procedures for noise control). Failure to approve or...

  8. Image quality associated with the use of an MR-compatible incubator in neonatal neuroimaging.

    PubMed

    O'Regan, K; Filan, P; Pandit, N; Maher, M; Fanning, N

    2012-04-01

    MRI in the neonate poses significant challenges associated with patient transport and monitoring, and the potential for diminished image quality owing to patient motion. The objective of this study was to evaluate the usefulness of a dedicated MR-compatible incubator with integrated radiofrequency coils in improving image quality of MRI studies of the brain acquired in term and preterm neonates using standard MRI equipment. Subjective and objective analyses of image quality of neonatal brain MR examinations were performed before and after the introduction of an MR-compatible incubator. For all studies, the signal-to-noise ratio (SNR) was calculated, image quality was graded (1-3) and each was assessed for image artefact (e.g. motion). Student's t-test and the Mann-Whitney U-test were used to compare mean SNR values. 39 patients were included [mean gestational age 39 weeks (range 30-42 weeks); mean postnatal age 13 days (range 1-56 days); mean weight 3.5 kg (range 1.4-4.5 kg)]. Following the introduction of the MR-compatible incubator, diagnostic quality scans increased from 50 to 89% and motion artefact decreased from 73 to 44% of studies. SNR did not increase initially, but, when using MR sequences and parameters specifically tailored for neonatal brain imaging, SNR increased from 70 to 213 (p=0.001). Use of an MR-compatible incubator in neonatal neuroimaging provides a safe environment for MRI of the neonate and also facilitates patient monitoring and transport. When specifically tailored MR protocols are used, this results in improved image quality.

  9. A Tol2 Gateway-Compatible Toolbox for the Study of the Nervous System and Neurodegenerative Disease.

    PubMed

    Don, Emily K; Formella, Isabel; Badrock, Andrew P; Hall, Thomas E; Morsch, Marco; Hortle, Elinor; Hogan, Alison; Chow, Sharron; Gwee, Serene S L; Stoddart, Jack J; Nicholson, Garth; Chung, Roger; Cole, Nicholas J

    2017-02-01

    Currently there is a lack in fundamental understanding of disease progression of most neurodegenerative diseases, and, therefore, treatments and preventative measures are limited. Consequently, there is a great need for adaptable, yet robust model systems to both investigate elementary disease mechanisms and discover effective therapeutics. We have generated a Tol2 Gateway-compatible toolbox to study neurodegenerative disorders in zebrafish, which includes promoters for astrocytes, microglia and motor neurons, multiple fluorophores, and compatibility for the introduction of genes of interest or disease-linked genes. This toolbox will advance the rapid and flexible generation of zebrafish models to discover the biology of the nervous system and the disease processes that lead to neurodegeneration.

  10. Coach/player relationships in tennis.

    PubMed

    Prapavessis, H; Gordon, S

    1991-09-01

    The present study examined the variables that predict coach/athlete compatibility. Compatibility among a sample of 52 elite tennis coach/player dyads was assessed using a sport adapted version of Schutz's (1966) Fundamental Interpersonal Relations Orientation-Behaviour (FIRO-B), a sport adapted version of Fiedler's (1967) Least Preferred Co-worker scale (LPC), and Chelladurai and Saleh's (1980) Leadership Scale for Sport (LSS). Self-ratings of the quality of the interaction were obtained from both coach and athlete. Multiple-regression analyses using self-rating scores as the dependent measure were carried out to determine which variables best predicted the degree of compatibility. The sole inventory that significantly predicted compatibility was the LSS. More specifically, the discrepancy between the athlete's preferences and perceptions on the autocratic dimension was the best predictor. Implications for tennis coaches and recommendations for future research in this area are discussed.

  11. Sensorless control for a sophisticated artificial myocardial contraction by using shape memory alloy fibre.

    PubMed

    Shiraishi, Y; Yambe, T; Saijo, Y; Sato, F; Tanaka, A; Yoshizawa, M; Sugai, T K; Sakata, R; Luo, Y; Park, Y; Uematsu, M; Umezu, M; Fujimoto, T; Masumoto, N; Liu, H; Baba, A; Konno, S; Nitta, S; Imachi, K; Tabayashi, K; Sasada, H; Homma, D

    2008-01-01

    The authors have been developing an artificial myocardium, which is capable of supporting natural contractile function from the outside of the ventricle. The system was originally designed by using sophisticated covalent shape memory alloy fibres, and the surface did not implicate blood compatibility. The purpose of our study on the development of artificial myocardium was to achieve the assistance of myocardial functional reproduction by the integrative small mechanical elements without sensors, so that the effective circulatory support could be accomplished. In this study, the authors fabricated the prototype artificial myocardial assist unit composed of the sophisticated shape memory alloy fibre (Biometal), the diameter of which was 100 microns, and examined the mechanical response by using pulse width modulation (PWM) control method in each unit. Prior to the evaluation of dynamic characteristics, the relationship between strain and electric resistance and also the initial response of each unit were obtained. The component for the PWM control was designed in order to regulate the myocardial contractile function, which consisted of an originally-designed RISC microcomputer with the input of displacement, and its output signal was controlled by pulse wave modulation method. As a result, the optimal PWM parameters were confirmed and the fibrous displacement was successfully regulated under the different heat transfer conditions simulating internal body temperature as well as bias tensile loading. Then it was indicated that this control theory might be applied for more sophisticated ventricular passive or active restraint by the artificial myocardium on physiological demand.

  12. 49 CFR 173.52 - Classification codes and compatibility groups of explosives.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Classification codes and compatibility groups of... Class 1 § 173.52 Classification codes and compatibility groups of explosives. (a) The classification..., consists of the division number followed by the compatibility group letter. Compatibility group letters are...

  13. Blood compatibility--a perspective.

    PubMed

    Ratner, B D

    2000-01-01

    This perspective on blood- materials interactions is intended to introduce the set of papers stemming from the symposium, "Devices and Diagnostics in Contact with Blood: Issues in Blood Compatibility at the Close of the 20th Century," organized on August 4-6, 1999 at the University of Washington by the University of Washington Engineered Biomaterials (UWEB) Engineering Research Center. This article outlines some of the history of blood contacting materials, overviews the work that has originated at the University of Washington over the past 28 years, speculates on the origins of the controversies on blood compatibility and considers the issues that should be addressed in future studies.

  14. A study of the applicability/compatibility of inertial energy storage systems to future space missions

    NASA Technical Reports Server (NTRS)

    Weldon, W. F.

    1980-01-01

    The applicability/compatibility of inertial energy storage systems like the homopolar generator (HPG) and the compensated pulsed alternator (CPA) to future space missions is explored. Areas of CPA and HPG design requiring development for space applications are identified. The manner in which acceptance parameters of the CPA and HPG scale with operating parameters of the machines are explored and the types of electrical loads which are compatible with the CPA and HPG are examined. Potential applications including the magnetoplasmadynamic (MPD) thruster, pulsed data transmission, laser ranging, welding and electromagnetic space launch are discussed.

  15. Classical r-matrices for the generalised Chern–Simons formulation of 3d gravity

    NASA Astrophysics Data System (ADS)

    Osei, Prince K.; Schroers, Bernd J.

    2018-04-01

    We study the conditions for classical r-matrices to be compatible with the generalised Chern–Simons action for 3d gravity. Compatibility means solving the classical Yang–Baxter equations with a prescribed symmetric part for each of the real Lie algebras and bilinear pairings arising in the generalised Chern–Simons action. We give a new construction of r-matrices via a generalised complexification and derive a non-linear set of matrix equations determining the most general compatible r-matrix. We exhibit new families of solutions and show that they contain some known r-matrices for special parameter values.

  16. Distinct Osmoadaptation Strategies in the Strict Halophilic and Halotolerant Bacteria Isolated from Lunsu Salt Water Body of North West Himalayas.

    PubMed

    Vaidya, Shivani; Dev, Kamal; Sourirajan, Anuradha

    2018-07-01

    Two strict halophilic bacterial strains, Halobacillus trueperi SS1, and Halobacillus trueperi SS3, and three halotolerant bacterial strains, Shewanella algae SS2, Halomonas venusta SS5, and Marinomonas sp. SS8 of Lunsu salt water body, Himachal Pradesh, India, were selected to study the mechanism of salt tolerance and the role of osmolytes therein. A combination of flame photometry, chromatographic and colorimetric assays was used to study the mechanism of salt tolerance in the selected strict halophilic and halotolerant bacterial strains. The strict halophiles and, one of the halotolerants, Marinomonas sp. SS8 were found to utilize both "salt-in strategy" and "accumulation of compatible solutes strategy" for osmoregulation in hypersaline conditions. On the contrary, the remaining two halotolerants used "accumulation of compatible solutes strategy" under saline stress and not the "salt-in strategy". The present study suggests towards distinct mechanisms of salt tolerance in the two classes, wherein strict halophiles accumulate compatible solutes as well as adopt salt-in strategy, while the halotolerant bacteria accumulate a range of compatible solutes, except Marinomonas sp. SS8, which utilizes both the strategies to combat salt stress.

  17. Low Prevalence of HIV Infection in Djibouti - Has the AIDS Epidemic Come to a Stop at the Horn of Africa?

    DTIC Science & Technology

    1989-01-01

    Abbatte’ Ministre de la Sante ernmost part of the Horn of Africa. Its inhabitants publique : Dr Albert; WHO, Djibouti: Dr Wassef; H6pital belong to...Research Unit No. 3, FPO, New York, NY entreprise : Dr Said; Cabinet Medical: Dr Rodier" and Mr 09527-1600, USA. Adel; Dispensaire de Randa: Dr Qufz&k...41 at the Service Medical Inter- entreprise , at the Nation- hospital patients with a disease compatible with al Army Health Centre, at the Service

  18. Domestic mobile satellite systems in North America

    NASA Technical Reports Server (NTRS)

    Wachira, Muya

    1990-01-01

    Telest Mobile Inc. (TMI) and the American Mobile Satellite Corporation (AMSC) are authorized to provide mobile satellite services (MSS) in Canada and the United States respectively. They are developing compatible systems and are undertaking joint specification and procurement of spacecraft and ground segment with the aim of operational systems by late 1993. Early entry (phase 1) mobile data services are offered in 1990 using space segment capacity leased from Inmarsat. Here, an overview is given of these domestic MSS with an emphasis on the TMI component of the MSAT systen.

  19. Skylab Rescue Space Vehicle OAT No. 1 Plugs in Test

    NASA Technical Reports Server (NTRS)

    Jevitt, S. J.

    1973-01-01

    A test is described which demonstrates the compatibility of the Skylab Rescue Space Vehicle systems, the ground support equipment, and off-site support facilities by proceeding through a simulated launch countdown, liftoff, and flight. The functions of propellant loading, umbilical ejection, holddown arm release, service arm retraction, liftoff, and inflight separation are simulated. An external power source supplies transfer power to internal, and instrument unit commands are simulated by the digital command system. The test outline is presented along with a list of references, intercommunications information, radio frequency matrix, and interface control chart.

  20. Cost Benefit Analysis of Expeditionary Warfare Training Group Atlantic Forward Air Controller / Joint Terminal Attack Controller Training Options

    DTIC Science & Technology

    2013-03-13

    Previous versions were signed in 2004, 2007, and 2010. The most recent version was signed 1 January 2012 by HQMC PPO and includes 17 United States DoD and...Amos) to Cdr USJFCOM - 21 Mar 2008 From CMC PPO POG: Ground Board discussion Collateral Duties of JTAC not compatible with primary duties MSG dtd...EWTGLANT Trng Cmd PPO APP MCSCG MARFORCOM USFFC CNAL CSFWL SFWSL CVW-X CVW-X OPNAV N-98 II MEF 2D MARDIV 2D MAW OPNAV N-95 NAWCTSD

  1. Basic EMC (Electromagnetic Compatibility) Technology Advancement for C3 Systems, Macromodeling of Digital Circuits. Volume 2B.

    DTIC Science & Technology

    1984-04-01

    dependent source to multiply a ramp by a unit sinusoid. Using this method, data could be extracted from a single run to show the magnitude of the...IHPUT VOLTAGE SOURCES VAC 1 0 0V VAl 2 0 0V VA2 3 0 0V VA3 4 0 PULSE(OV 3V ONSD 2NSR 2NSF 198NSPW) VB0 5 0 OV VB1 6 0 OV VB2 7 0 CV VB3 8 0 PULSE

  2. Evaluation of Maltose-Induced Chemical Degradation at the Interface of Bilayer Tablets.

    PubMed

    Matsuzaki, Naoya; Yamamoto, Yousuke; Murayama, Daisuke; Katakawa, Yoshifumi; Mimura, Hisashi; Kimura, Shin-Ichiro; Iwao, Yasunori; Itai, Shigeru

    2017-01-01

    Fixed dose combination tablets consisting of mirabegron (MB) and solifenacin succinate (SS) were developed and formulated into bilayer tablets in the current study. The results of a chemical stability study showed that the original formulation for the tablets led to a significant increase of unknown degradants in the SS layer. Two compatibility studies were conducted to simulate the interface between the MB and SS layers, and the results revealed that the degradants only formed in the presence of both active pharmaceutical ingredients (APIs), and that the presence of maltose in the SS layer was critical to inducing degradation. High resolution mass spectroscopy coupled with high performance liquid chromatography was used to determine the chemical structures of the degradants, which were identified to MB derivatives bearing one or two sugar units. These findings therefore suggested that the degradation of the API could be attributed to the addition of sugar units from maltose to MB under the acidic conditions caused by SS. With this in mind, we developed a new formulation by replacing maltose with hydroxypropyl cellulose as a polymer-type binder. The results showed that this formulation suppressed the formation of the degradants. The results of this study have shown that chemical degradation can occur at the interface of bilayer tablets and that an alternative strategy is available to formulate more stable MB/SS bilayer tablets.

  3. A Closed-Loop Proportional-Integral (PI) Control Software for Fully Mechanically Controlled Automated Electron Microscopic Tomography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    REN, GANG; LIU, JINXIN; LI, HONGCHANG

    A closed-loop proportional-integral (PI) control software is provided for fully mechanically controlled automated electron microscopic tomography. The software is developed based on Gatan DigitalMicrograph, and is compatible with Zeiss LIBRA 120 transmission electron microscope. However, it can be expanded to other TEM instrument with modification. The software consists of a graphical user interface, a digital PI controller, an image analyzing unit, and other drive units (i.e.: image acquire unit and goniometer drive unit). During a tomography data collection process, the image analyzing unit analyzes both the accumulated shift and defocus value of the latest acquired image, and provides the resultsmore » to the digital PI controller. The digital PI control compares the results with the preset values and determines the optimum adjustments of the goniometer. The goniometer drive unit adjusts the spatial position of the specimen according to the instructions given by the digital PI controller for the next tilt angle and image acquisition. The goniometer drive unit achieves high precision positioning by using a backlash elimination method. The major benefits of the software are: 1) the goniometer drive unit keeps pre-aligned/optimized beam conditions unchanged and achieves position tracking solely through mechanical control; 2) the image analyzing unit relies on only historical data and therefore does not require additional images/exposures; 3) the PI controller enables the system to dynamically track the imaging target with extremely low system error.« less

  4. China’s Muslims: Separatism and Prospects for Ethnic Peace

    DTIC Science & Technology

    2006-09-01

    Management and Budget, Paperwork Reduction Project (0704-0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE September...unlike Uighur ethnic identity, Hui identity stems from and is compatible with the PRC and Chinese society. This study uses primary sources including...and is compatible with the PRC and Chinese society. This study uses primary sources including interviews with Uighurs, Hui and Han Chinese conducted

  5. Anisotropic membranes for gas separation

    DOEpatents

    Gollan, A.Z.

    1987-07-21

    A gas separation membrane has a dense separating layer about 10,000 Angstroms or less thick and a porous support layer 10 to 400 microns thick that is an integral unit with gradually and continuously decreasing pore size from the base of the support layer to the surface of the thin separating layer and is made from a casting solution comprising ethyl cellulose and ethyl cellulose-based blends, typically greater than 47.5 ethoxyl content ethyl cellulose blended with compatible second polymers, such as nitrocellulose. The polymer content of the casting solution is from about 10% to about 35% by weight of the total solution with up to about 50% of this polymer weight a compatible second polymer to the ethyl cellulose in a volatile solvent such as isopropanol, methylacetate, methanol, ethanol, and acetone. Typical nonsolvents for the casting solutions include water and formamide. The casting solution is cast in air from about zero to 10 seconds to allow the volatile solvent to evaporate and then quenched in a coagulation bath, typically water, at a temperature of 7--25 C and then air dried at ambient temperature, typically 10--30 C. 2 figs.

  6. Joint helmet-mounted cueing system (JHMCS) helmet qualification testing requirements

    NASA Astrophysics Data System (ADS)

    Orf, Garry W.

    1998-08-01

    The Joint Helmet-Mounted Cueing System (JHMCS) program will provide capability to cue high off-boresight (HOBS) weapons to the operator's line of sight and to confirm weapon sensor LOS for the US Air Force and US Navy (USN) aircrew. This capability will ensure the USAF and USN pilots a first shot opportunity. The JHMCS incorporates an ejection-compatible helmet-mounted display system that will be installed on F- 15, F-16, F/A-18, and F-22 aircraft. The JHMCS includes a flight helmet with display optics, miniature cathode ray tube, magnetic receiver unit, miniature camera, automatic brightness control sensor, and microcontroller. The flight helmet for JHMCS is based on the new lightweight HGU-55A/P. This paper describes the requirements for the helmet qualification tests including: windblast, ejection tower, hanging harness, centrifuge, mass properties, energy attenuation and penetration resistance, noise attenuation, visor characteristics, compatibility demonstration, sled/in- flight ejection, water survival, standard conditions and environment. The test objective, success criteria, equipment configuration, and data collection requirements for each test is discussed.

  7. The Effect of Nonmasking Distractors on the Priming of Motor Responses

    ERIC Educational Resources Information Center

    Jaskowski, Piotr

    2007-01-01

    Masked stimuli (primes) can affect the preparation of a motor response to subsequently presented target. In numerous studies, it has been shown that the compatibility effect is biphasic as it develops over time: positive (benefits for compatible trials and costs for incompatible trials) for short prime-target temporal distances and negative…

  8. The Compatibility of Feminist Theology and Gestalt Therapy: A Study of "Practical-Values."

    ERIC Educational Resources Information Center

    Hinksman, Barrie

    2001-01-01

    An on-going theoretical issue for pastoral counseling concerns the integration of psychological and theological concepts. The possibility of exploring the compatibility of Gestalt psychotherapy and feminist theology is considered with reference to the 'practical-values' of each, and it is proposed that there is significant common ground between…

  9. Does Felt Gender Compatibility Mediate Influences of Self-Perceived Gender Nonconformity on Early Adolescents' Psychosocial Adjustment?

    ERIC Educational Resources Information Center

    Menon, Meenakshi

    2011-01-01

    This study evaluated the hypothesis that self-perceived gender nonconformity is distressing to children because it undermines a confident sense of gender compatibility. Participants were 357 early adolescents (180 boys, M age = 12.68 years) in England who responded to questionnaires measuring friendship styles (preoccupied, avoidant), gender…

  10. Micro-Macro Compatibility: When Does a Complex Systems Approach Strongly Benefit Science Learning?

    ERIC Educational Resources Information Center

    Samon, Sigal; Levy, Sharona T.

    2017-01-01

    The study explores how a complexity approach empowers science learning. A complexity approach represents systems as many interacting entities. The construct of micro-macro compatibility is introduced, the degree of similarity between behaviors at the micro- and macro-levels of the system. Seventh-grade students' learning about gases was studied…

  11. [Study on membrane type leaf water evaporation inhibitors for improving effect of preventing diseases and pest controlling of Lycium barbarum].

    PubMed

    Wang, Dan-Dan; Lv, Zhe; Xu, Chang-Qing; Liu, Sai; Chen, Jun; Peng, Xiao; Wu, Yan

    2018-01-01

    Through indoor and field comparative experiments, the properties of membrane type leaf evaporation inhibitors and its effects on photosynthesis of Lycium barbarum and compatibility and synergistic of pesticide were studied. The evaporation inhibitors and L. barbarum were chosen to investigate the suppression of water evaporation and the compatibility with pesticides. The effect of evaporation inhibitors on photosynthesis of L. barbarum leaves was determined by the chlorophyll fluorescence imaging system. The results showed that water evaporation of L. barbarum leaves of different leaf age were evidently suppressed after treated with evaporation inhibitor. The inhibitor was well compatible with pesticide and effectively improved the pesticide efficacy,and had no significant effect on chlorophyll fluorescence parameters. It is concluded that the evaporation inhibitor has good compatibility with the pesticide, and has remarkable effect of restraining moisture evaporation, which make it can be used for reducing the dosage and improving the efficacy of the pesticide in the field of L. barbarum. Copyright© by the Chinese Pharmaceutical Association.

  12. Gender compatibility, math-gender stereotypes, and self-concepts in math and physics

    NASA Astrophysics Data System (ADS)

    Koul, Ravinder; Lerdpornkulrat, Thanita; Poondej, Chanut

    2016-12-01

    [This paper is part of the Focused Collection on Gender in Physics.] Positive self-assessment of ability in the quantitative domains is considered critical for student participation in science, technology, engineering, and mathematics field studies. The present study investigated associations of gender compatibility (gender typicality and contentedness) and math-gender stereotypes with self-concepts in math and physics. Statistical analysis of survey data was based on a sample of 170 male and female high school science students matched on propensity scores based on age and past GPA scores in math. Results of MANCOVA analyses indicated that the combination of high personal gender compatibility with low endorsement of math-gender stereotypes was associated with low gender differentials in math and physics self-concepts whereas the combination of high personal gender compatibility with high endorsement of math-gender stereotypes was associated with high gender differentials in math and physics self-concepts. These results contribute to the recent theoretical and empirical work on antecedents to the math and physics identities critical to achieving gender equity in STEM fields.

  13. Compatibility art of traditional Chinese medicine: from the perspective of herb pairs.

    PubMed

    Wang, Shengpeng; Hu, Yangyang; Tan, Wen; Wu, Xu; Chen, Ruie; Cao, Jiliang; Chen, Meiwan; Wang, Yitao

    2012-09-28

    Over the past decades, research of traditional Chinese medicine (TCM) mainly focused on developing potential candidates from Chinese medicinal herbs, while the wisdom of applying these traditional herbs has not been paid as much attention as it deserves. As is well-known, multi-herb therapy is one of the most important characteristics of TCM, but the modernization drive of this conventional wisdom has faced many obstacles due to its unimaginable complexity. Herb pairs, the most fundamental and the simplest form of multi-herb formulae, are a centralized representative of Chinese herbal compatibility. In light of their simplicity and the basic characteristics of complex formulae, herb pairs are of great importance in the studies of herb compatibility. A systematic search of herb pair related research was carried out using multiple online literature databases, books and monographs published in the past 20 years. A comprehensive introduction to the compatibility of TCM, the position of herb pairs in TCM and the progresses of several famous herb pairs were provided in this review. Furthermore, the clinical study and the future research trends of herb pairs were also discussed. Herb pairs have played, and may continue to play a key role in full investigation of general herb compatibility for their indispensable position in TCM. Much more research is needed for the standardization, safety evaluation, and mechanism exploration of herb pairs. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  14. Study on the blood compatibility and biodegradation properties of magnesium alloys.

    PubMed

    Mochizuki, Akira; Kaneda, Hideki

    2015-02-01

    Lately, several magnesium alloys have been investigated as a new class of biomaterials owing to their excellent biodegradability in living tissues. In this study, we considered AZ series of Mg alloy containing aluminum (3% to 9%) and zinc (1%) as a model magnesium alloy, and investigated their biodegradation in whole blood and blood compatibility in vitro. The results of the elution property of metal ions determined using chromogenic assay and the associated pH change show that the degradation resistance of the AZ series alloys in blood is improved by alloying aluminum. Furthermore, the blood compatibility of the alloys was investigated in terms of their hemolysis, factor Xa-like activity, using spectrophotometry and chromogenic assay, respectively, and coagulation time measurements (prothrombin time and activated partial thromboplastin time). The results indicated that the blood compatibility of the AZ series alloys is excellent, irrespective of the alloy composition. The excellent blood compatibility with the coagulation system could be attributed to the eluted Mg(2+) ion, which suppresses the activation of certain coagulation factors in the intrinsic and/or extrinsic coagulation pathways. In terms of the degradation resistance of the AZ series alloys in blood, the results of pH change in blood and the amount of the eluted metal ions indicate that the performance is markedly improved with an increase in aluminum content. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Visual context modulates potentiation of grasp types during semantic object categorization.

    PubMed

    Kalénine, Solène; Shapiro, Allison D; Flumini, Andrea; Borghi, Anna M; Buxbaum, Laurel J

    2014-06-01

    Substantial evidence suggests that conceptual processing of manipulable objects is associated with potentiation of action. Such data have been viewed as evidence that objects are recognized via access to action features. Many objects, however, are associated with multiple actions. For example, a kitchen timer may be clenched with a power grip to move it but pinched with a precision grip to use it. The present study tested the hypothesis that action evocation during conceptual object processing is responsive to the visual scene in which objects are presented. Twenty-five healthy adults were asked to categorize object pictures presented in different naturalistic visual contexts that evoke either move- or use-related actions. Categorization judgments (natural vs. artifact) were performed by executing a move- or use-related action (clench vs. pinch) on a response device, and response times were assessed as a function of contextual congruence. Although the actions performed were irrelevant to the categorization judgment, responses were significantly faster when actions were compatible with the visual context. This compatibility effect was largely driven by faster pinch responses when objects were presented in use-compatible, as compared with move-compatible, contexts. The present study is the first to highlight the influence of visual scene on stimulus-response compatibility effects during semantic object processing. These data support the hypothesis that action evocation during conceptual object processing is biased toward context-relevant actions.

  16. Compatibility Assessment of Fuel System Thermoplastics with Bio-Blendstock Fuel Candidates Using Hansen Solubility Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kass, Michael D.; West, Brian H.

    The compatibility of key fuel system infrastructure plastics with 39 bio-blendstock fuel candidates was examined using Hansen solubility analysis. Fuel types included multiple alcohols, esters, ethers, ketones, alkenes and one alkane. These compounds were evaluated as neat molecules and as blends with the gasoline surrogate, dodecane, and a mix of dodecane and 10% ethanol (E10D). The plastics included polyphenylene sulfide (PPS), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), polyvinylidene fluoride (PVDF), polyoxymethylene (POM), polybutylene terephthalate (PBT), polypropylene (PP), high density polyethylene (HDPE), along with several nylon grades. These materials have been rigorously studied with other fuel types, and their volume change resultsmore » were found to correspond well with their predicted solubility levels.The compatibility was assessed using Hansen solubility parameters and in many instances peak solubility occurred for blends rather than the neat fuel components. The results showed that good compatibilities can be expected for PPS, PVDF, PET, nylons, acetal, PEI, PVC, HDPE and PBT. PTFE showed potential incompatibilities at low blend concentrations, especially when E10D was used as the base fuel blend. Although, the nylons show good overall compatibility, the results do indicate that mid-range and high alcohol contents may not be suitable for Nylon 6 and Nylon 11 in applications requiring low volume swell. Poor potential compatibility was limited to two plastic types; PETG exposed to mid and high blend levels of the ethers and PP exposed to sabinene and the aromatics. In general, the data showed good compatibility for the majority of the candidate fuels and plastics.« less

  17. Compatibility Assessment of Fuel System Thermoplastics with Bio-Blendstock Fuel Candidates Using Hansen Solubility Analysis

    DOE PAGES

    Kass, Michael D.; West, Brian H.

    2018-01-03

    The compatibility of key fuel system infrastructure plastics with 39 bio-blendstock fuel candidates was examined using Hansen solubility analysis. Fuel types included multiple alcohols, esters, ethers, ketones, alkenes and one alkane. These compounds were evaluated as neat molecules and as blends with the gasoline surrogate, dodecane, and a mix of dodecane and 10% ethanol (E10D). The plastics included polyphenylene sulfide (PPS), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), polyvinylidene fluoride (PVDF), polyoxymethylene (POM), polybutylene terephthalate (PBT), polypropylene (PP), high density polyethylene (HDPE), along with several nylon grades. These materials have been rigorously studied with other fuel types, and their volume change resultsmore » were found to correspond well with their predicted solubility levels.The compatibility was assessed using Hansen solubility parameters and in many instances peak solubility occurred for blends rather than the neat fuel components. The results showed that good compatibilities can be expected for PPS, PVDF, PET, nylons, acetal, PEI, PVC, HDPE and PBT. PTFE showed potential incompatibilities at low blend concentrations, especially when E10D was used as the base fuel blend. Although, the nylons show good overall compatibility, the results do indicate that mid-range and high alcohol contents may not be suitable for Nylon 6 and Nylon 11 in applications requiring low volume swell. Poor potential compatibility was limited to two plastic types; PETG exposed to mid and high blend levels of the ethers and PP exposed to sabinene and the aromatics. In general, the data showed good compatibility for the majority of the candidate fuels and plastics.« less

  18. Loss of compatibility might explain resistance of the Arabidopsis thaliana accession Te-0 to Golovinomyces cichoracearum.

    PubMed

    Fabro, Georgina; Alvarez, María Elena

    2012-08-11

    The establishment of compatibility between plants and pathogens requires compliance with various conditions, such as recognition of the right host, suppression of defence mechanisms, and maintenance of an environment allowing pathogen reproduction. To date, most of the plant factors required to sustain compatibility remain unknown, with the few best characterized being those interfering with defence responses. A suitable system to study host compatibility factors is the interaction between Arabidopsis thaliana and the powdery mildew (PM) Golovinomyces cichoracearum. As an obligate biotrophic pathogen, this fungus must establish compatibility in order to perpetuate. In turn, A. thaliana displays natural variation for susceptibility to this invader, with some accessions showing full susceptibility (Col-0), and others monogenic dominant resistance (Kas-1). Interestingly, Te-0, among other accessions, displays recessive partial resistance to this PM. In this study, we characterized the interaction of G. cichoracearum with Te-0 plants to investigate the basis of this plant resistance. We found that Te-0's incompatibility was not associated with hyper-activation of host inducible defences. Te-0 plants allowed germination of conidia and development of functional haustoria, but could not support the formation of mature conidiophores. Using a suppressive subtractive hybridization technique, we identified plant genes showing differential expression between resistant Te-0 and susceptible Col-0 plants at the fungal pre-conidiation stage. Te-0 resistance is likely caused by loss of host compatibility and not by stimulation of inducible defences. Conidiophores formation is the main constraint for completion of fungal life cycle in Te-0 plants. The system here described allowed the identification of genes proposed as markers for susceptibility to this PM.

  19. Comparison of online reporting systems and their compatibility check with respective adverse drug reaction reporting forms.

    PubMed

    Maharshi, Vikas; Nagar, Pravesh

    2017-01-01

    Different forms and online tools are available in different countries for spontaneous reporting, one of the most widely used methods of pharmacovigilance. Capturing sufficient information and adequate compatibility of online systems with respective reporting form is highly desirable for appropriate reporting of adverse drug reactions (ADRs). This study was aimed to compare three major online reporting systems (US, UK, and WHO) of the world and also to check their compatibility with the respective ADR reporting form. A total of 89 data elements to provide relevant information were found out from above three online reporting systems. All three online systems were compared regarding magnitude of information captured by each of them and scoring was done by providing a score of "1" to each element. Compatibility of ADR reporting forms of India (Red form), US (Form 3500), and UK (Yellow card form) was assessed by comparing the information gathered by them with that can be entered into their respective online reporting systems, namely, "VigiFlow," "US online reporting," and "Yellow card online reporting." Each unmatching item was given a score of "-1". VigiFlow scored "74" points, whereas online reporting systems of the US and UK scored "56" and "49," respectively, regarding magnitude of the information gathered by them. Compatibility score was found to be "0," "-9," and "-26" in case of ADR reporting systems of US, UK, and India, respectively. Our study reveals that "VigiFlow" is capable of capturing the maximum amount of information but "Form 3500" and "Online reporting system of US" are maximally compatible to each other among ADR reporting systems of all three countries.

  20. Variation in floral morphology and plant reproductive success in four Ipomoea species (Convolvulaceae) with contrasting breeding systems.

    PubMed

    Delgado-Dávila, R; Martén-Rodríguez, S; Huerta-Ramos, G

    2016-11-01

    This study tested the hypothesis that self-compatibility would be associated with floral traits that facilitate autonomous self-pollination to ensure reproduction under low pollinator visitation. In a comparison of two pairs of Ipomoea species with contrasting breeding systems, we predicted that self-compatible (SC) species would have smaller, less variable flowers, reduced herkogamy, lower pollinator visitation and higher reproductive success than their self-incompatible (SI) congeners. We studied sympatric species pairs, I. hederacea (SC)- I. mitchellae (SI) and I. purpurea (SC)-I. indica (SI), in Mexico, over two years. We quantified variation in floral traits and nectar production, documented pollinator visitation, and determined natural fruit and seed set. Hand-pollination and bagging experiments were conducted to determine potential for autonomous self-pollination and apomixis. Self-compatible Ipomoea species had smaller flowers and lower nectar production than SI species; however, floral variation and integration did not vary according to breeding system. Bees were primary pollinators of all species, but visitation rates were seven times lower in SC than SI species. SC species had a high capacity for autonomous self-pollination due to reduced herkogamy at the highest anther levels. Self-compatible species had two to six times higher fruit set than SI species. Results generally support the hypothesis that self-compatibility and autonomous self-pollination ensure reproduction under low pollinator visitation. However, high variation in morphological traits of SC Ipomoea species suggests they maintain variation through outcrossing. Furthermore, reduced herkogamy was associated with high potential for autonomous self-pollination, providing a reproductive advantage that possibly underlies transitions to self-compatibility in Ipomoea. © 2016 German Botanical Society and The Royal Botanical Society of the Netherlands.

  1. Loss of compatibility might explain resistance of the Arabidopsis thaliana accession Te-0 to Golovinomyces cichoracearum

    PubMed Central

    2012-01-01

    Background The establishment of compatibility between plants and pathogens requires compliance with various conditions, such as recognition of the right host, suppression of defence mechanisms, and maintenance of an environment allowing pathogen reproduction. To date, most of the plant factors required to sustain compatibility remain unknown, with the few best characterized being those interfering with defence responses. A suitable system to study host compatibility factors is the interaction between Arabidopsis thaliana and the powdery mildew (PM) Golovinomyces cichoracearum. As an obligate biotrophic pathogen, this fungus must establish compatibility in order to perpetuate. In turn, A. thaliana displays natural variation for susceptibility to this invader, with some accessions showing full susceptibility (Col-0), and others monogenic dominant resistance (Kas-1). Interestingly, Te-0, among other accessions, displays recessive partial resistance to this PM. Results In this study, we characterized the interaction of G. cichoracearum with Te-0 plants to investigate the basis of this plant resistance. We found that Te-0´s incompatibility was not associated with hyper-activation of host inducible defences. Te-0 plants allowed germination of conidia and development of functional haustoria, but could not support the formation of mature conidiophores. Using a suppressive subtractive hybridization technique, we identified plant genes showing differential expression between resistant Te-0 and susceptible Col-0 plants at the fungal pre-conidiation stage. Conclusions Te-0 resistance is likely caused by loss of host compatibility and not by stimulation of inducible defences. Conidiophores formation is the main constraint for completion of fungal life cycle in Te-0 plants. The system here described allowed the identification of genes proposed as markers for susceptibility to this PM. PMID:22883024

  2. Magnetic resonance imaging-compatible circular mapping catheter: an in vivo feasibility and safety study.

    PubMed

    Elbes, Delphine; Magat, Julie; Govari, Assaf; Ephrath, Yaron; Vieillot, Delphine; Beeckler, Christopher; Weerasooriya, Rukshen; Jais, Pierre; Quesson, Bruno

    2017-03-01

    Interventional cardiac catheter mapping is routinely guided by X-ray fluoroscopy, although radiation exposure remains a significant concern. Feasibility of catheter ablation for common flutter has recently been demonstrated under magnetic resonance imaging (MRI) guidance. The benefit of catheter ablation under MRI could be significant for complex arrhythmias such as atrial fibrillation (AF), but MRI-compatible multi-electrode catheters such as Lasso have not yet been developed. This study aimed at demonstrating the feasibility and safety of using a multi-electrode catheter [magnetic resonance (MR)-compatible Lasso] during MRI for cardiac mapping. We also aimed at measuring the level of interference between MR and electrophysiological (EP) systems. Experiments were performed in vivo in sheep (N = 5) using a multi-electrode, circular, steerable, MR-compatible diagnostic catheter. The most common MRI sequences (1.5T) relevant for cardiac examination were run with the catheter positioned in the right atrium. High-quality electrograms were recorded while imaging with a maximal signal-to-noise ratio (peak-to-peak signal amplitude/peak-to-peak noise amplitude) ranging from 5.8 to 165. Importantly, MRI image quality was unchanged. Artefacts induced by MRI sequences during mapping were demonstrated to be compatible with clinical use. Phantom data demonstrated that this 10-pole circular catheter can be used safely with a maximum of 4°C increase in temperature. This new MR-compatible 10-pole catheter appears to be safe and effective. Combining MR and multipolar EP in a single session offers the possibility to correlate substrate information (scar, fibrosis) and EP mapping as well as online monitoring of lesion formation and electrical endpoint. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  3. Performance consequences of alternating directional control-response compatibility: evidence from a coal mine shuttle car simulator.

    PubMed

    Zupanc, Christine M; Burgess-Limerick, Robin J; Wallis, Guy

    2007-08-01

    To investigate error and reaction time consequences of alternating compatible and incompatible steering arrangements during a simulated obstacle avoidance task. Underground coal mine shuttle cars provide an example of a vehicle in which operators are required to alternate between compatible and incompatible steering configurations. This experiment examines the performance of 48 novice participants in a virtual analogy of an underground coal mine shuttle car. Participants were randomly assigned to a compatible condition, an incompatible condition, an alternating condition in which compatibility alternated within and between hands, or an alternating condition in which compatibility alternated between hands. Participants made fewer steering direction errors and made correct steering responses more quickly in the compatible condition. Error rate decreased over time in the incompatible condition. A compatibility effect for both errors and reaction time was also found when the control-response relationship alternated; however, performance improvements over time were not consistent. Isolating compatibility to a hand resulted in reduced error rate and faster reaction time than when compatibility alternated within and between hands. The consequences of alternating control-response relationships are higher error rates and slower responses, at least in the early stages of learning. This research highlights the importance of ensuring consistently compatible human-machine directional control-response relationships.

  4. The Role of Representation Strength of the Prime in Subliminal Visuomotor Priming.

    PubMed

    Wang, Yongchun; Wang, Yonghui; Liu, Peng; Di, Meilin; Gong, Yanyan; Tan, Mengge

    2017-11-01

    This study investigated the role of representation strength of the prime in subliminal visuomotor priming in two experiments. Prime/target compatibility (compatible and incompatible) and preposed object type (jumbled lines, strong masking; and rectangular outlines, weak masking) were manipulated in Experiment 1. A significant negative compatibility effect (NCE) was observed in the rectangle condition, whereas no compatibility effect was found in the line condition. However, when a new variable, prime duration, was introduced in Experiment 2, the NCE was reversed with an increase in the prime duration in the rectangle condition, whereas the NCE was maintained in the line condition. This result is consistent with the claim that increasing the prime duration causes the prime representation to be too strong for inhibition in the rectangle condition but strong enough to reliably trigger inhibition in the line condition. The findings demonstrated that prime representation has a causal role in subliminal visuomotor priming.

  5. Compatibility and consistency in display-control systems - Implications for aircraft decision aid design

    NASA Technical Reports Server (NTRS)

    Andre, Anthony D.; Wickens, Christopher D.

    1992-01-01

    In this study we contrast display-control movement relations defined in terms of stimulus-response (physical) compatibility with those defined by stimulus-cognitive compatibility, and we relate these findings to the issue of command versus status levels of decision aid support. A second issue addressed is the cost of inconsistency across multiple display-control mappings. Subjects performed a flight control task while responding to one to four analog indicators, formatted as either command or status displays. The results suggest that there is an advantage for the status format when subjects are required to verbally report the state of the indicator(s), but no advantage was found for either format when subjects were required to manually correct the indicated state. The data point to the importance of display-control consistency and suggest that it may even outweigh that of compatibility.

  6. A rapid compatibility analysis of potential offshore sand sources for beaches of the Santa Barbara Littoral Cell

    USGS Publications Warehouse

    Mustain, N.; Griggs, G.; Barnard, P.L.

    2007-01-01

    The beaches of the Santa Barbara Littoral Cell, which are narrow as a result of either natural and/or anthropogenic factors, may benefit from nourishment. Sand compatibility is fundamental to beach nourishment success and grain size is the parameter often used to evaluate equivalence. Only after understanding which sand sizes naturally compose beaches in a specific cell, especially the smallest size that remains on the beach, can the potential compatibility of source areas, such as offshore borrow sites, be accurately assessed. This study examines sediments on the beach and in the nearshore (5-20m depth) for the entire Santa Barbara Littoral Cell east of Point Conception. A digital bed sediment camera, the Eyeball??, and spatial autocorrelation technique were used to determine sediment grain size. Here we report on whether nearshore sediments are comparable and compatible with beach sands of the Santa Barbara Littoral Cell. ?? 2007 ASCE.

  7. Space shuttle OMS helium regulator design and development

    NASA Technical Reports Server (NTRS)

    Wichmann, H.; Kelly, T. L.; Lynch, R.

    1974-01-01

    Analysis, design, fabrication and design verification testing was conducted on the technological feasiblity of the helium pressurization regulator for the space shuttle orbital maneuvering system application. A prototype regulator was fabricated which was a single-stage design featuring the most reliable and lowest cost concept. A tradeoff study on regulator concepts indicated that a single-stage regulator with a lever arm between the valve and the actuator section would offer significant weight savings. Damping concepts were tested to determine the amount of damping required to restrict actuator travel during vibration. Component design parameters such as spring rates, effective area, contamination cutting, and damping were determined by test prior to regulator final assembly. The unit was subjected to performance testing at widely ranging flow rates, temperatures, inlet pressures, and random vibration levels. A test plan for propellant compatibility and extended life tests is included.

  8. Operational flight evaluation of the two-segment approach for use in airline service

    NASA Technical Reports Server (NTRS)

    Schwind, G. K.; Morrison, J. A.; Nylen, W. E.; Anderson, E. B.

    1975-01-01

    United Airlines has developed and evaluated a two-segment noise abatement approach procedure for use on Boeing 727 aircraft in air carrier service. In a flight simulator, the two-segment approach was studied in detail and a profile and procedures were developed. Equipment adaptable to contemporary avionics and navigation systems was designed and manufactured by Collins Radio Company and was installed and evaluated in B-727-200 aircraft. The equipment, profile, and procedures were evaluated out of revenue service by pilots representing government agencies, airlines, airframe manufacturers, and professional pilot associations. A system was then placed into scheduled airline service for six months during which 555 two-segment approaches were flown at three airports by 55 airline pilots. The system was determined to be safe, easy to fly, and compatible with the airline operational environment.

  9. Silicon material task - Low cost solar array project /JPL/DOE/

    NASA Technical Reports Server (NTRS)

    Lutwack, R.

    1979-01-01

    The paper describes the silicon material task of the low-cost solar array project, which has the objective of establishing a silicon production capability equivalent to 500 mW per year at a price less than 10 dollars/kg (1975 dollars) in 1986. The task program is divided into four phases: technical feasibility, scale-up studies (the present phase), experimental process system development units, and implementation of large-scale production plants, and it involves the development of processes for two groups of materials, that is, semiconductor grade and solar cell grade. In addition, the effects of impurities on solar cell performance are being investigated. Attention is given to problem areas of the task program, such as environmental protection, material compatibility between the reacting chemicals and materials of construction of the equipment, and waste disposal.

  10. He Says, She Says: Gender and Cohabitation*

    PubMed Central

    Huang, Penelope M.; Smock, Pamela J.; Manning, Wendy D.; Bergstrom-Lynch, Cara A.

    2010-01-01

    Cohabitation has become the modal path to marriage in the United States. However, little is known about what cohabitation means to young adults today. Drawing on data from 18 focus groups (N=138) and 54 in-depth interviews with young adults, this exploratory study investigates motivations to cohabit, and examines potential gender differences in those motivations and the meanings attached to them. We find that primary motives to cohabit include spending time together, sharing expenses, and evaluating compatibility. Strong gender differences emerge in how respondents discuss these themes and how they characterize the drawbacks of cohabitation, with men more concerned about loss of freedom and women with delays in marriage. Overall, our findings suggest that gendered cultural norms governing intimate relationships extend to cohabiting unions, and point to gender differences in the perceived role of cohabitation in union formation processes. PMID:21643456

  11. Incompatible type A plasma transfusion in patients requiring massive transfusion protocol: Outcomes of an Eastern Association for the Surgery of Trauma multicenter study.

    PubMed

    Stevens, W Tait; Morse, Bryan C; Bernard, Andrew; Davenport, Daniel L; Sams, Valerie G; Goodman, Michael D; Dumire, Russell; Carrick, Matthew M; McCarthy, Patrick; Stubbs, James R; Pritts, Timothy A; Dente, Christopher J; Luo-Owen, Xian; Gregory, Jason A; Turay, David; Gomaa, Dina; Quispe, Juan C; Fitzgerald, Caitlin A; Haddad, Nadeem N; Choudhry, Asad; Quesada, Jose F; Zielinski, Martin D

    2017-07-01

    With a relative shortage of type AB plasma, many centers have converted to type A plasma for resuscitation of patients whose blood type is unknown. The goal of this study is to determine outcomes for trauma patients who received incompatible plasma transfusions as part of a massive transfusion protocol (MTP). As part of an Eastern Association for the Surgery of Trauma multi-institutional trial, registry and blood bank data were collected from eight trauma centers for trauma patients (age, ≥ 15 years) receiving emergency release plasma transfusions as part of MTPs from January 2012 to August 2016. Incompatible type A plasma was defined as transfusion to patient blood type B or type AB. Of the 1,536 patients identified, 92% received compatible plasma transfusions and 8% received incompatible type A plasma. Patient characteristics were similar except for greater penetrating injuries (48% vs 36%; p = 0.01) in the incompatible group. In the incompatible group, patients were transfused more plasma units at 4 hours (median, 9 vs. 5; p < 0.001) and overall for stay (11 vs. 9; p = 0.03). No hemolytic transfusion reactions were reported. Two transfusion-related acute lung injury events were reported in the compatible group. Between incompatible and compatible groups, there was no difference in the rates of acute respiratory distress syndrome (6% vs. 8%; p = 0.589), thromboembolic events (9% vs. 7%; p = 0.464), sepsis (6% vs. 8%; p = 0.589), or acute renal failure (8% vs. 8%, p = 0.860). Mortality at 6 (17% vs. 15%, p = 0.775) and 24 hours (25% vs. 23%, p = 0.544) and at 28 days or discharge (38% vs. 35%, p = 0.486) were similar between groups. Multivariate regression demonstrated that Injury Severity Score, older age and more red blood cell transfusion at 4 hours were independently associated with death at 28 days or discharge; Injury Severity Score and more red blood cell transfusion at 4 hours were predictors for morbidity. Incompatible transfusion was not an independent determinant of mortality or morbidity. Transfusion of type A plasma to patients with blood groups B and AB as part of a MTP does not appear to be associated with significant increases in morbidity or mortality. Therapeutic study, level IV.

  12. Compatibility: drugs and parenteral nutrition

    PubMed Central

    Miranda, Talita Muniz Maloni; Ferraresi, Andressa de Abreu

    2016-01-01

    ABSTRACT Objective Standardization and systematization of data to provide quick access to compatibility of leading injectable drugs used in hospitals for parenteral nutrition. Methods We selected 55 injectable drugs analyzed individually with two types of parenteral nutrition: 2-in-1 and 3-in-1. The following variables were considered: active ingredient, compatibility of drugs with the parenteral nutrition with or without lipids, and maximum drug concentration after dilution for the drugs compatible with parenteral nutrition. Drugs were classified as compatible, incompatible and untested. Results After analysis, relevant information to the product’s compatibility with parental nutrition was summarized in a table. Conclusion Systematization of compatibility data provided quick and easy access, and enabled standardizing pharmacists work. PMID:27074235

  13. Solid state compatibility study and characterization of a novel degradation product of tacrolimus in formulation.

    PubMed

    Rozman Peterka, Tanja; Grahek, Rok; Hren, Jure; Bastarda, Andrej; Bergles, Jure; Urleb, Uroš

    2015-06-10

    Tacrolimus is macrolide drug that is widely used as a potent immunosuppressant. In the present work compatibility testing was conducted on physical mixtures of tacrolimus with excipients and on compatibility mixtures prepared by the simulation of manufacturing process used for the final drug product preparation. Increase in one major degradation product was detected in the presence of magnesium stearate based upon UHPLC analysis. The degradation product was isolated by preparative HPLC and its structure was elucidated by NMR and MS studies. Mechanism of the formation of this degradation product is proposed based on complementary degradation studies in a solution and structural elucidation data. The structure was proven to be alpha-hydroxy acid which is formed from the parent tacrolimus molecule through a benzilic acid type rearrangement reaction in the presence of divalent metallic cations. Degradation is facilitated at higher pH values. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Compatible Spatial Discretizations for Partial Differential Equations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arnold, Douglas, N, ed.

    From May 11--15, 2004, the Institute for Mathematics and its Applications held a hot topics workshop on Compatible Spatial Discretizations for Partial Differential Equations. The numerical solution of partial differential equations (PDE) is a fundamental task in science and engineering. The goal of the workshop was to bring together a spectrum of scientists at the forefront of the research in the numerical solution of PDEs to discuss compatible spatial discretizations. We define compatible spatial discretizations as those that inherit or mimic fundamental properties of the PDE such as topology, conservation, symmetries, and positivity structures and maximum principles. A wide varietymore » of discretization methods applied across a wide range of scientific and engineering applications have been designed to or found to inherit or mimic intrinsic spatial structure and reproduce fundamental properties of the solution of the continuous PDE model at the finite dimensional level. A profusion of such methods and concepts relevant to understanding them have been developed and explored: mixed finite element methods, mimetic finite differences, support operator methods, control volume methods, discrete differential forms, Whitney forms, conservative differencing, discrete Hodge operators, discrete Helmholtz decomposition, finite integration techniques, staggered grid and dual grid methods, etc. This workshop seeks to foster communication among the diverse groups of researchers designing, applying, and studying such methods as well as researchers involved in practical solution of large scale problems that may benefit from advancements in such discretizations; to help elucidate the relations between the different methods and concepts; and to generally advance our understanding in the area of compatible spatial discretization methods for PDE. Particular points of emphasis included: + Identification of intrinsic properties of PDE models that are critical for the fidelity of numerical simulations. + Identification and design of compatible spatial discretizations of PDEs, their classification, analysis, and relations. + Relationships between different compatible spatial discretization methods and concepts which have been developed; + Impact of compatible spatial discretizations upon physical fidelity, verification and validation of simulations, especially in large-scale, multiphysics settings. + How solvers address the demands placed upon them by compatible spatial discretizations. This report provides information about the program and abstracts of all the presentations.« less

  15. Screening for mutations in exon 4 of the LDL receptor gene: identification of a new deletion mutation.

    PubMed Central

    Theart, L; Kotze, M J; Langenhoven, E; Loubser, O; Peeters, A V; Lintott, C J; Scott, R S

    1995-01-01

    DNA from 14 unrelated New Zealand familial hypercholesterolaemia (FH) heterozygotes, originating from the United Kingdom, was screened for mutations in exon 4 of the low density lipoprotein receptor (LDLR) gene. One patient was heterozygous for mutation D206E, which was initially identified in South Africa. The chromosomal background of this mutant allele was compatible with that described previously in Afrikaner and English patients, suggesting that this mutation originated in the United Kingdom. The 2 bp deletion in codon 206 and mutations D154N and D200G, previously reported in English FH patients, were not detected in this sample. In one of the patients, however, a new deletion of 7 bp was identified after nucleotide 581 (or 582) in exon 4 of the LDLR gene. Images PMID:7616546

  16. Experimental Investigations from the Operation of a 2 Kw Brayton Power Conversion Unit and a Xenon Ion Thruster

    NASA Technical Reports Server (NTRS)

    Mason, Lee; Birchenough, Arthur; Pinero, Luis

    2004-01-01

    A 2 kW Brayton Power Conversion Unit (PCU) and a xenon ion thruster were integrated with a Power Management and Distribution (PMAD) system as part of a Nuclear Electric Propulsion (NEP) Testbed at NASA's Glenn Research Center. Brayton converters and ion thrusters are potential candidates for use on future high power NEP missions such as the proposed Jupiter Icy Moons Orbiter (JIMO). The use of existing lower power test hardware provided a cost-effective means to investigate the critical electrical interface between the power conversion system and ion propulsion system. The testing successfully demonstrated compatible electrical operations between the converter and the thruster, including end-to-end electric power throughput, high efficiency AC to DC conversion, and thruster recycle fault protection. The details of this demonstration are reported herein.

  17. Experimental Investigation from the Operation of a 2 kW Brayton Power Conversion Unit and a Xenon Ion Thruster

    NASA Technical Reports Server (NTRS)

    Hervol, David; Mason, Lee; Birchenough, Art; Pinero, Luis

    2004-01-01

    A 2kW Brayton Power Conversion Unit (PCU) and a xenon ion thruster were integrated with a Power Management and Distribution (PMAD) system as part of a Nuclear Electric Propulsion (NEP) Testbed at NASA's Glenn Research Center. Brayton Converters and ion thrusters are potential candidates for use on future high power NEP mission such as the proposed Jupiter Icy Moons Orbiter (JIMO). The use of a existing lower power test hardware provided a cost effective means to investigate the critical electrical interface between the power conversion system and the propulsion system. The testing successfully demonstrated compatible electrical operations between the converter and the thruster, including end-to-end electric power throughput, high efficiency AC to DC conversion, and thruster recycle fault protection. The details of this demonstration are reported herein.

  18. Polymer Brushes Containing Sulfonated Sugar Repeat Units: Synthesis, Characterization and In Vitro Testing of Blood Coagulation Activation

    PubMed Central

    Ayres, N.; Holt, D. J.; Jones, C.F.; Corum, L. E.; Grainger, D. W.

    2009-01-01

    A new polymer brush chemistry containing sulfonated carbohydrate repeat units has been synthesized from silicon substrates using ATRP methods and characterized both in bulk and using surface analysis. The polymer brush was designed to act as a mimic for the naturally occurring sulfonated glycosaminoglycan, heparin, commonly used for modifying blood-contacting surfaces both in vitro and in vivo. Surface analysis showed conversion of brush saccharide precursor chemistry to the desired sulfonated polymer product. The sulfonated polymer brush surface was further analyzed using three conventional in vitro tests for blood compatibility -- plasma recalcification times, complement activation, and thrombin generation. The sulfonated polymer brush films on silicon oxide wafers exhibited better assay performance in these blood component assays than the unsulfonated sugar functionalized polymer brush in all tests performed. PMID:19859552

  19. Neural coding of repetitive clicks in the medial geniculate body of cat.

    PubMed

    Rouiller, E; de Ribaupierre, Y; Toros-Morel, A; de Ribaupierre, F

    1981-09-01

    The activity of 418 medial geniculate body (MGB) units was studied in response to repetitive acoustic pulses in 35 nitrous oxide anaesthetized cats. The proportion of MGB neurons insensitive to repetitive clicks was close to 30%. On the basis of their pattern of discharge, the responsive units were divided into three categories. The majority of them (71%), classified as "lockers', showed discharges precisely time-locked to the individual clicks of the train. A few units (8%), called "groupers', had discharges loosely synchronized to low-rate repetitive clicks. When the spikes were not synchronized, the cell had transient or sustained responses for a limited frequency range and was classified as a "special responder' (21%). Responses of "lockers' were time-locked up to a limiting rate, which varied between 10 and 800 Hz; half of the "lockers' had a limiting rate of locking equal to or higher than 100 Hz. The degree of entrainment, defined as the probability that each click evokes at least one spike, regularly decreases for increasing rates; on the other hand, the precision of locking increasing increases with frequency. The time jitter observed at 100 Hz might be as small as 0.2 ms and was 1.2 ms on average. The population of "lockers' can mark with precision the transients of complex sounds and has response properties still compatible with a temporal coding of the fundamental frequency of most animal vocalizations.

  20. [Study on processing adjuvant medicines in Lei Gong's treatise on preparation and broiling of materia medica (Leigong Paozhi Lun)].

    PubMed

    Zhang, Wei; Zhang, Ruixian

    2010-09-01

    There were 268 kinds of medicines recorded in the book of Lei Gong's Treatise on preparation and broiling of materia medica (Leigong Paozhi Lun). Among these medicines, 178 medicines were prepared with adjuvant medicines, including general and special compatible adjuvant medicines. These adjuvant medicines used in this book can be explained by the theory of "seven-relation compatibility". The author tried to explain the usage and their compatibility of these adjuvant medicines and put forward that attention should be paid to the changes in functions of medicines and the influences of society should be paid attention.

  1. Hemisphere division and its effect on selective attention: a generality examination of Lavie's load theory.

    PubMed

    Nishimura, Ritsuko; Yoshizaki, Kazuhito; Kato, Kimiko; Hatta, Takeshi

    2009-01-01

    The present study examined the role of visual presentation mode (unilateral vs. bilateral visual fields) on attentional modulation. We examined whether or not the presentation mode affects the compatibility effect, using a paradigm involving two task-relevant letter arrays. Sixteen participants identified a target letter among task-relevant letters while ignoring either a compatible or incompatible distracter letter that was presented to both hemispheres. Two letters arrays were presented to visual fields, either unilaterally or bilaterally. Results indicated that the compatibility effect was greater in bilateral than in unilateral visual field conditions. Findings support the assumption that the two hemispheres have separate attentional resources.

  2. A method for improved visual landscape compatibility of mobile home park

    Treesearch

    Daniel R. Jones

    1979-01-01

    This paper is a description of a research effort directed to improving the visual image of mobile home parks in the landscape. The study is an application of existing methodologies for measuring scenic quality and visual landscape compatibility to an unsolved problem. The paper summarizes two major areas of investigation: regional location factors based on visual...

  3. Cooperation, Convertibility, and Compatibility Among Information Systems: A Literature Review.

    ERIC Educational Resources Information Center

    Henderson, Madeline M.; And Others

    The purpose of the study of the literature on which this report is based was to examine those problems in the field of documentation and in the operation of information systems which could possibly be solved or alleviated by some greater measure of cooperation, convertibility, or compatibility among systems, particularly those systems for handling…

  4. An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography.

    PubMed

    Glover, Paul M; Watkins, Roger H; O'Neill, George C; Ackerley, Rochelle; Sanchez-Panchuelo, Rosa; McGlone, Francis; Brookes, Matthew J; Wessberg, Johan; Francis, Susan T

    2017-10-01

    Intra-neural microstimulation (INMS) is a technique that allows the precise delivery of low-current electrical pulses into human peripheral nerves. Single unit INMS can be used to stimulate individual afferent nerve fibres during microneurography. Combining this with neuroimaging allows the unique monitoring of central nervous system activation in response to unitary, controlled tactile input, with functional magnetic resonance imaging (fMRI) providing exquisite spatial localisation of brain activity and magnetoencephalography (MEG) high temporal resolution. INMS systems suitable for use within electrophysiology laboratories have been available for many years. We describe an INMS system specifically designed to provide compatibility with both ultra-high field (7T) fMRI and MEG. Numerous technical and safety issues are addressed. The system is fully analogue, allowing for arbitrary frequency and amplitude INMS stimulation. Unitary recordings obtained within both the MRI and MEG screened-room environments are comparable with those obtained in 'clean' electrophysiology recording environments. Single unit INMS (current <7μA, 200μs pulses) of individual mechanoreceptive afferents produces appropriate and robust responses during fMRI and MEG. This custom-built MRI- and MEG-compatible stimulator overcomes issues with existing INMS approaches; it allows well-controlled switching between recording and stimulus mode, prevents electrical shocks because of long cable lengths, permits unlimited patterns of stimulation, and provides a system with improved work-flow and participant comfort. We demonstrate that the requirements for an INMS-integrated system, which can be used with both fMRI and MEG imaging systems, have been fully met. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  5. Family directed umbilical cord blood banking for acute leukemia: usage rate in hematopoietic stem cell transplantation.

    PubMed

    Screnci, M; Murgi, E; Tamburini, A; Pecci, M R; Ballatore, G; Cusanno, A; Valle, V; Luciani, P; Corona, F; Girelli, G

    2015-04-01

    Family-directed umbilical cord blood (UCB) collection and banking is indicated in women delivering healthy babies who already have a member of their own family with a disease potentially treatable with an allogeneic hematopoietic stem cell (HSCs) transplantation (HSCT). The rapid availability of UCB is an important issue in HSCs procurement particularly for recipients with acute leukemia who urgently need HSCT. The aims of this study were to assess the usage rate of family UCB collections directed to patients with acute leukemia and to investigate the factors influencing the usage rate. A total of 113 families were enrolled, 118 UCB units were successfully collected and one collection failed due to emergency occurred during delivery. Among these, 7 collections were required for children who were in urgent need of a transplant: three HLA-matched units were successfully transplanted, respectively after 2, 5 and 6 months from collection; three collections resulted HLA-mismatched, while HLA-typing is pending for one unit. The remaining collections were mostly required for potential future use, among these units only one was transplanted in a HLA compatible sibling after 3 years and 4 months from collection. After a median time of storage of 8.5 years (range 0.1-20 years) a total of 4/118 (3.4 %) collection has been transplanted. During this time interval, considering only patients who have had the need of a transplant, the main factor influencing low utilization rate of UCB collections was due to HLA disparity, indeed among typed UCB unit mostly (77 %) resulted HLA mismatched with the intended recipient.

  6. Quality control of colonoscopy procedures: a prospective validated method for the evaluation of professional practices applicable to all endoscopic units.

    PubMed

    Coriat, R; Pommaret, E; Chryssostalis, A; Viennot, S; Gaudric, M; Brezault, C; Lamarque, D; Roche, H; Verdier, D; Parlier, D; Prat, F; Chaussade, S

    2009-02-01

    To produce valid information, an evaluation of professional practices has to assess the quality of all practices before, during and after the procedure under study. Several auditing techniques have been proposed for colonoscopy. The purpose of this work is to describe a straightforward original validated method for the prospective evaluation of professional practices in the field of colonoscopy applicable in all endoscopy units without increasing the staff work load. Pertinent quality-control criteria (14 items) were identified by the endoscopists at the Cochin Hospital and were compatible with: findings in the available literature; guidelines proposed by the Superior Health Authority; and application in any endoscopy unit. Prospective routine data were collected and the methodology validated by evaluating 50 colonoscopies every quarter for one year. The relevance of the criteria was assessed using data collected during four separate periods. The standard checklist was complete for 57% of the colonoscopy procedures. The colonoscopy procedure was appropriate according to national guidelines in 94% of cases. These observations were particularly noteworthy: the quality of the colonic preparation was insufficient for 9% of the procedures; complete colonoscopy was achieved for 93% of patients; and 0.38 adenomas and 0.045 carcinomas were identified per colonoscopy. This simple and reproducible method can be used for valid quality-control audits in all endoscopy units. In France, unit-wide application of this method enables endoscopists to validate 100 of the 250 points required for continuous medical training. This is a quality-control tool that can be applied annually, using a random month to evaluate any changes in routine practices.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Colldelram, Carles, E-mail: ccolldelram@cells.es; Nicolas, Josep, E-mail: jnicolas@cells.es; Nikitina, Liudmila, E-mail: lnikitina@cells.es

    In this work we report the design and performance of a novel compact in-vacuum actuator, designed to be compatible with all the motions required for the scissor-type ESRF mirror bender. These mirror benders include several linear actuators, which drive the mirror bending torques, as well as the main alignment motions such as pitch and translation along the normal to the mirror surface. The motions are provided by compact linear actuators, which consist of motor, reduction, spindle and nut, encapsulated on a closed air volume to provide vacuum compatibility. The actuator includes a hydroformed bellows to transmit the force to themore » actuator tip, and an electrical feedthrough for the motor cables. The design boundaries for these actuators are quite tight, as they must be integrated in a narrow volume, must be UHV compatible and must provide high resolution, for a relatively high load. As a result, they have limited mechanical performance, and in some cases poor reliability. To overcome these problems, we designed and implemented a different concept. In the proposed concept, the motor rotation is converted onto a linear motion by means of a cam instead of a spindle and a nut. This allows for much shorter and stiffer transmission system, with similar dimensions. The vacuum compatibility is intrinsic for this solution, since the whole mechanism of the actuator is UHV compatible. All motions are preloaded and guided by vacuum compatible (hybrid metal-ceramics) ball bearings. This allows the system reaching a repeatability and backlash well within the micron. The absence of friction allows for a high reliability and releases the maintenance needs of the system. The transmission is intrinsically irreversible, and the system can hold a load of 250 N within a few nanometers without any holding current on the motors. This allows the system to move reliably also in micro-stepping mode, providing a resolution well below the half-step nominal resolution of 100 nm. Performances have been tested on a prototype. We report the results of the tests obtained in air and in vacuum after bake-out. Two units of the new actuator have been installed at the photoemission beamline of ALBA (CIRCE) and are routinely used to align the 3 µm spot on the field of view of the Photoemission Electron Microscope. The absence of any noticeable backlash, or any friction effect and the reliability of the micro-stepping motion has simplified very much the alignment of the photon beam, reducing the alignment process to few minutes. The excellent performances and relatively high load capacity of this new compact actuator make of it a versatile element to be integrated in other systems requiring reliable in-vacuum positioning.« less

  8. The compatibility of consumer DLP projectors with time-sequential stereoscopic 3D visualisation

    NASA Astrophysics Data System (ADS)

    Woods, Andrew J.; Rourke, Tegan

    2007-02-01

    A range of advertised "Stereo-Ready" DLP projectors are now available in the market which allow high-quality flickerfree stereoscopic 3D visualization using the time-sequential stereoscopic display method. The ability to use a single projector for stereoscopic viewing offers a range of advantages, including extremely good stereoscopic alignment, and in some cases, portability. It has also recently become known that some consumer DLP projectors can be used for timesequential stereoscopic visualization, however it was not well understood which projectors are compatible and incompatible, what display modes (frequency and resolution) are compatible, and what stereoscopic display quality attributes are important. We conducted a study to test a wide range of projectors for stereoscopic compatibility. This paper reports on the testing of 45 consumer DLP projectors of widely different specifications (brand, resolution, brightness, etc). The projectors were tested for stereoscopic compatibility with various video formats (PAL, NTSC, 480P, 576P, and various VGA resolutions) and video input connections (composite, SVideo, component, and VGA). Fifteen projectors were found to work well at up to 85Hz stereo in VGA mode. Twenty three projectors would work at 60Hz stereo in VGA mode.

  9. Harnessing Scientific and Technological Advances to Improve Equity in Kidney Allocation Policies.

    PubMed

    Tambur, A R; Audry, B; Antoine, C; Suberbielle, C; Glotz, D; Jacquelinet, C

    2017-12-01

    We reported that current assignment of HLA-DQ is a barrier to organ allocation. Here we simulated the impact of incorporating HLA-DQ antigens and antibodies as A/B and αβ allelic variants, respectively, on calculated panel reactive antibody (cPRA) and probability of finding potential compatible donors (PCD). A cohort of 1224 donors and 2075 sensitized candidates was analyzed using HLA-DQαβ allelic (study) versus serologic (current practice) nomenclature. A significant (p < 10 -4 ) decrease in cPRA was observed with higher impact for male versus female, and first transplant versus retransplant (p < 10 -4 ), affecting mostly patients with moderate cPRA (30-80%). Consequently, the number of patients qualifying for 100% cPRA points according to the United Network for Organ Sharing-Kidney Allocation System decreased by 37%. More critically, by using allelic versus serologic nomenclature for HLA-DQ, the number of PCDs for all patients was increased, with male and first-transplant patients showing a higher expansion compared with female and retransplants. Patients of blood group O showed the highest benefit. The goal of reporting unacceptable antigens is to improve accuracy of virtual crossmatching and increase the likelihood of finding immunologically compatible donors. Our simulation provides strong support for the need to re-evaluate the use of allele typing and how HLA-DQ antigens and antibodies are incorporated into allocation policies to ensure equity. © 2017 The American Society of Transplantation and the American Society of Transplant Surgeons.

  10. Polar2Grid 2.0: Reprojecting Satellite Data Made Easy

    NASA Astrophysics Data System (ADS)

    Hoese, D.; Strabala, K.

    2015-12-01

    Polar-orbiting multi-band meteorological sensors such as those on the Suomi National Polar-orbiting Partnership (SNPP) satellite pose substantial challenges for taking imagery the last mile to forecast offices, scientific analysis environments, and the general public. To do this quickly and easily, the Cooperative Institute for Meteorological Satellite Studies (CIMSS) at the University of Wisconsin has created an open-source, modular application system, Polar2Grid. This bundled solution automates tools for converting various satellite products like those from VIIRS and MODIS into a variety of output formats, including GeoTIFFs, AWIPS compatible NetCDF files, and NinJo forecasting workstation compatible TIFF images. In addition to traditional visible and infrared imagery, Polar2Grid includes three perceptual enhancements for the VIIRS Day-Night Band (DNB), as well as providing the capability to create sharpened true color, sharpened false color, and user-defined RGB images. Polar2Grid performs conversions and projections in seconds on large swaths of data. Polar2Grid is currently providing VIIRS imagery over the Continental United States, as well as Alaska and Hawaii, from various Direct-Broadcast antennas to operational forecasters at the NOAA National Weather Service (NWS) offices in their AWIPS terminals, within minutes of an overpass of the Suomi NPP satellite. Three years after Polar2Grid development started, the Polar2Grid team is now releasing version 2.0 of the software; supporting more sensors, generating more products, and providing all of its features in an easy to use command line interface.

  11. [Prevalence of urinary and anal incontinence in women from metropolitan area of Guadalajara].

    PubMed

    Martínez Espinoza, Claudia Josefina; Flores Carreras, Oscar; García de Alba García, Javier E; Velázquez Castellanos, Patricia Inés; González Ruiz, María Isabel; Márquez Allegre, René

    2006-06-01

    Female urinary and anal incontinence are common entities in pelvic floor dysfunction. The most frequently age affected range from 45 to 69 years. Previous studies performed in the United States report a prevalence of 24-62% for urinary incontinence and 3-60% for anal incontinence. To determine the prevalence of these disorders in the Guadalajara metropolitan area because we do not know it. A transversal and various stage study was performed recollecting blocks first, then houses, finally interviewing women and applying a structured questionnaire with somatometric and social-demographic data and also clinical-pathological antecedents. The data obtained was registered and processed first manually then using Excel and Epi-Info software. The group of women interviewed (n = 352) were between 15-85 years. The majority were married, housewives, 33% with grammar school, 23% finished high school, 25% professionists and 19% did not finish school; with an average of three pregnancies and with a body mass index (BMI) positive for overweight and obesity. The prevalence for urinary incontinence was 27.8% and anal incontinence of 3.4%. These are results compatible with those reported in the United States. Women living in Guadalajara have the same behavior that European and American women about prevalence of urinary incontinence. We recommend the performance of this type of studies in other states of this country in order to enrich the present information.

  12. Microbial utilisation of natural organic wastes

    NASA Astrophysics Data System (ADS)

    Ilyin, V. K.; Smirnov, I. A.; Soldatov, P. E.; Korniushenkova, I. N.; Grinin, A. S.; Lykov, I. N.; Safronova, S. A.

    2004-03-01

    The waste management strategy for the future should meet the benefits of humanity safety, respect principals of planet ecology, and compatibility with other habitability systems. For these purpose the waste management technologies, relevant to application of the biodegradation properties of bacteria are of great value. The biological treatment method is based upon the biodegradation of organic substances by various microorganisms. The advantage of the biodegradation waste management in general: it allows to diminish the volume of organic wastes, the biological hazard of the wastes is controlled and this system may be compatible with the other systems. The objectives of our study were: to evaluate effectiveness of microbial biodegradation of non-pretreated substrate, to construct phneumoautomatic digester for organic wastes biodegradation and to study microbial characteristics of active sludge samples used as inoculi in biodegradation experiment. The technology of vegetable wastes treatment was elaborated in IBMP and BMSTU. For this purpose the special unit was created where the degradation process is activated by enforced reinvention of portions of elaborated biogas into digester. This technology allows to save energy normally used for electromechanical agitation and to create optimal environment for anaerobic bacteria growth. The investigations were performed on waste simulator, which imitates physical and chemical content of food wastes calculated basing on the data on food wastes of moderate Russian city. The volume of created experimental sample of digester is 40 l. The basic system elements of device are digesters, gas receiver, remover of drops and valve monitoring and thermal control system. In our testing we used natural food wastes to measure basic parameters and time of biodegradation process. The diminution rate of organic gained 76% from initial mass taking part within 9 days of fermentation. The biogas production achieved 46 l per 1 kg of substrate. The microbial studies of biodegradation process revealed following peculiarities: gradual quantitative increasing of Lactobacillus sp. (from 10 3 to 10 5 colony forming units (CFU) per ml), activation of Clostridia sp. (from 10 2 to 10 4 CFU/ml) and elimination of aerobic conventional pathogens ( Enterobacteriaceae sp., Protea sp., staphylococci). The obtained results allow to evaluate effectiveness of proposed technology and to determine the leading role of lactobacilli and clostridia in process of natural wastes biodegradation. Our further investigations shall further be concentrated on creation of artificial inoculi for launching of food wastes biodegradation. These inoculi will include active and adapted strains of clostridia and lactobacilli.

  13. Electromagnetic Compatibility Design of the Computer Circuits

    NASA Astrophysics Data System (ADS)

    Zitai, Hong

    2018-02-01

    Computers and the Internet have gradually penetrated into every aspect of people’s daily work. But with the improvement of electronic equipment as well as electrical system, the electromagnetic environment becomes much more complex. Electromagnetic interference has become an important factor to hinder the normal operation of electronic equipment. In order to analyse the computer circuit compatible with the electromagnetic compatibility, this paper starts from the computer electromagnetic and the conception of electromagnetic compatibility. And then, through the analysis of the main circuit and system of computer electromagnetic compatibility problems, we can design the computer circuits in term of electromagnetic compatibility. Finally, the basic contents and methods of EMC test are expounded in order to ensure the electromagnetic compatibility of equipment.

  14. Military aircrew eyewear survey: operational issues.

    PubMed

    Capó-Aponte, José E; Hilber, David J; Urosevich, Thomas G; Lattimore, Morris R; Weaver, Jeffrey L

    2013-08-01

    Army aircrew are required to operate under stressful conditions within a degraded visual environment. To gain an understanding of current eyewear mission needs, we surveyed aircrew regarding operational issues associated with the current U.S. Army-issue aircrew eyewear. An anonymous online survey was completed by 976 U.S. Army aircrew personnel recruited through an invitational e-mail. Of the respondents, 34% reported wearing corrective lenses. Nearly 50% of them reported dissatisfaction with the HGU-4/P Aviator spectacles. The leading problems reported were discomfort (15%), "hot spots" around the ears (13%), and break of the earcup seal (11%). Nearly 41% of the respondents wore multifocal lenses and, of those, 16% reported that the HGU-4/P's restricted field of view (FOV) adversely affected duty performance. Of those who wore Modified HGU-4/P Apache spectacles, 79% had an unacceptable FOV with the helmet display unit. A similar number of aircrew modified the Apache eyewear to increase the FOV. In addition, wind and dust created eye discomfort or affected the vision of 46% of all respondents when performing flight duties. Over 82% expressed the need for an improved aircrew spectacles and 73% desired aviation-compatible protective eyewear. The current Army HGU-4/P Aviator and the Modified HGU-4/P Apache spectacles have significant operational deficiencies and compatibility issues. Such deficiencies have led to poor wear compliance and unauthorized modification of the Army-issue Aviator eyewear, posing readiness and safety issues. The results of this survey formally identify the need for military combat eye protection that is compatible with flight systems.

  15. Physical and Chemical Compatibility of Injectable Acetaminophen During Simulated Y-Site Administration

    PubMed Central

    Anderson, Collin; Boehme, Sabrina; Ouellette, Jacquelyn; Stidham, Chanelle; MacKay, Mark

    2014-01-01

    Purpose: The physical and chemical compatibility of intravenous acetaminophen with commonly administered injectable medications was evaluated. Methods: Simulated Y-site evaluation was accomplished by mixing 2 mL of acetaminophen (10 mg/mL) with 2 mL of an alternative intravenous medication and subsequently storing the mixture in a polypropylene syringe for 4 hours. The aliquot solutions were visually inspected and evaluated for crystal content at 4 hours by infusing 4 mL of the medication mixture through a 0.45-μm nitrocellulose filter disc. Medication mixtures that were selected for chemical stability testing were analyzed by high-performance liquid chromatography at 0, 1, and 4 hours using a Zorbax Eclipse Plus C18, 4.6 x 100 mm, 3.5-μm column for separation of analytes with subsequent diode-array detection. Medications were considered chemically compatible if the concentrations of all components were >90% of the original concentrations during the 4 hour simulated Y-site compatibility test. Results: U.S. Pharmacopeial Convention (USP) standards for physical particle counts were met for acetaminophen injection (10 mg/mL) when combined with cefoxitin, ceftriaxone, clindamycin, dexamethasone, diphenhydramine, dolasetron, fentanyl, granisetron, hydrocortisone, hydromorphone, ketorolac, meperidine, methylprednisolone, midazolam, morphine, nalbuphine, ondansetron, piperacillin/tazobactam, ranitidine, and vancomycin. Injectable acetaminophen is incompatible with acyclovir and diazepam and therefore should not be administered concomitantly with either of these products. Further testing confirmed the chemical compatibility of acetaminophen with ceftriaxone, diphenhydramine, granisetron, ketorolac, nalbuphine, ondansetron, piperacillin/tazobactam, and vancomycin. Conclusion: All medications tested with acetaminophen were physically compatible except for acyclovir and diazepam. All 8 medications tested for chemical compatibility with acetaminophen were stable over the 4 hour simulated Y-site administration study. PMID:24421562

  16. Socialization in Pigtailed Macaques (Macaca nemestrina)

    PubMed Central

    WORLEIN, JULIE M.; KROEKER, ROSE; LEE, GRACE H.; THOM, JINHEE P.; BELLANCA, RITA U.; CROCKETT, CAROLYN M.

    2018-01-01

    In response to new emphasis by regulatory agencies regarding socialization, behavioral management programs are allocating greater resources to maximize socialization opportunities for laboratory primates. Information regarding predictors of compatibility and risk of injury for all laboratory-housed species of macaques are needed to make social introductions and pairings as efficient and safe as possible. This study presents data on 674 pairs of pigtailed macaques (Macaca nemestrina) at the Washington National Primate Research Center over a 7-year period. During pair introduction, behavior was monitored while the degree of tactile contact was gradually increased. Based on observed behavior, pairs were assigned a behavioral introduction score (BIS), rating the quality of their interactions for each day of introduction. Animals deemed compatible, based on the BIS and technologist judgment, were allowed to progress to continuous contact with no staff present. A small proportion of animals deemed compatible at introduction was later separated for subsequent incompatibility or aggression; these proportions were higher in full contact compared to protected contact pairings. Of 674 pairs, 75% were deemed compatible at introduction in protected contact; 86 of these pairs were later transitioned to full contact with 98% compatibility. Predictors of decreased compatibility assessed during protected contact introductions included age (adult pairs were less compatible), the BIS on the last day of introduction, and aggression or injury during the introductory period. Predictors of injuries during the protected contact introduction process included: aggression on the first day of introduction, a negative BIS on the first or last day of introduction, and, surprisingly, the presence of grooming on the first day of introduction. Injuries during both introduction and subsequent pairing in protected contact were rare; however, injury rates increased significantly during full-contact pairing. These findings underscore the necessity of species-specific data to guide decision-making during the social introduction process. PMID:27109591

  17. Compatibility Conditions of Structural Mechanics

    NASA Technical Reports Server (NTRS)

    Patnaik, Surya N.; Coroneos, Rula M.; Hopkins, Dale A.

    1999-01-01

    The theory of elasticity has camouflaged a deficiency in the compatibility formulation since 1860. In structures the ad hoc compatibility conditions through virtual "cuts" and closing "gaps" are not parallel to the strain formulation in elasticity. This deficiency in the compatibility conditions has prevented the development of a direct stress determination method in structures and in elasticity. We have addressed this deficiency and attempted to unify the theory of compatibility. This work has led to the development of the integrated force method for structures and the completed Beltrami-Michell formulation for elasticity. The improved accuracy observed in the solution of numerical examples by the integrated force method can be attributed to the compliance of the compatibility conditions. Using the compatibility conditions allows mapping of variables and facile movement among different structural analysis formulations. This paper reviews and illustrates the requirement of compatibility in structures and in elasticity. It also describes the generation of the conditions and quantifies the benefits of their use. The traditional analysis methods and available solutions (which have been obtained bypassing the missed conditions) should be verified for compliance of the compatibility conditions.

  18. Assessing the compatibility of the management of standardized procedures with the complexity of a sociotechnical system: case study of a control room in an oil refinery.

    PubMed

    Saurin, Tarcisio Abreu; Gonzalez, Santiago Sosa

    2013-09-01

    Although the need for the management of complex socio-technical systems (STS) to be compatible with the nature of those systems is widely recognized, there are few guidelines on how to determine the actual extent of this compatibility. The purpose of this study is to assess how compatible the management of standardized procedures (SPs) is with the nature of a complex STS. To this end, a case study was made of a control room in an oil refinery, involving the following stages: (a) delimitation of the investigated STS; (b) description of the STS according to a set of characteristics of complex STS; (c) application of two types of questionnaires to thirty workers - one of them to assess their perceptions about the applicability of seven principles of SPs management in complex STS and the other to determine their perceptions about the actual use of these principles; and (d) a feedback meeting with workers to discuss the results of the assessment. The assessment is discussed in terms of its limitations, usefulness and ease of use of the data collection and analysis tools. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  19. Pulsed magnetic field excitation sensitivity of match-type electric blasting caps

    NASA Astrophysics Data System (ADS)

    Parson, Jonathan; Dickens, James; Walter, John; Neuber, Andreas A.

    2010-10-01

    This paper presents a study on energy deposition and electromagnetic compatibility of match-type electroexplosive devices (EEDs), which recently have found more usage in pulsed power environments with high electromagnetic interference (EMI) background. The sensitivity of these devices makes them dangerous to intended and unintended radiation produced by devices commonly used in pulsed power environments. Match-type EEDs have been found to be susceptible to such low levels of energy (7-8 mJ) that safe operation of these EEDs is vital when in use near devices that produce high levels of pulsed EMI. The scope of this paper is to provide an investigation that incorporates results of similar studies to provide detonation characteristics of these EEDs. The three topics included in this study are sensitivity testing, modeling of the thermodynamic heat propagation, and electromagnetic compatibility from pulsed electromagnetic radiation. The thermodynamic joule heating of the primary explosive has been modeled by a solution to the 1D heat equation. A simple pulsed generator, Marx generator with an inductive load, was used for the electromagnetic compatibility assessment of the coupled field between the pulse generator and shorted EED. The results of the electromagnetic compatibility assessment relate the resistive, inductive, and capacitive components of the pulse generator to the area of the shorted EED.

  20. Pulsed magnetic field excitation sensitivity of match-type electric blasting caps.

    PubMed

    Parson, Jonathan; Dickens, James; Walter, John; Neuber, Andreas A

    2010-10-01

    This paper presents a study on energy deposition and electromagnetic compatibility of match-type electroexplosive devices (EEDs), which recently have found more usage in pulsed power environments with high electromagnetic interference (EMI) background. The sensitivity of these devices makes them dangerous to intended and unintended radiation produced by devices commonly used in pulsed power environments. Match-type EEDs have been found to be susceptible to such low levels of energy (7-8 mJ) that safe operation of these EEDs is vital when in use near devices that produce high levels of pulsed EMI. The scope of this paper is to provide an investigation that incorporates results of similar studies to provide detonation characteristics of these EEDs. The three topics included in this study are sensitivity testing, modeling of the thermodynamic heat propagation, and electromagnetic compatibility from pulsed electromagnetic radiation. The thermodynamic joule heating of the primary explosive has been modeled by a solution to the 1D heat equation. A simple pulsed generator, Marx generator with an inductive load, was used for the electromagnetic compatibility assessment of the coupled field between the pulse generator and shorted EED. The results of the electromagnetic compatibility assessment relate the resistive, inductive, and capacitive components of the pulse generator to the area of the shorted EED.

  1. Mapping Curie temperature depth in the western United States with a fractal model for crustal magnetization

    USGS Publications Warehouse

    Bouligand, C.; Glen, J.M.G.; Blakely, R.J.

    2009-01-01

    We have revisited the problem of mapping depth to the Curie temperature isotherm from magnetic anomalies in an attempt to provide a measure of crustal temperatures in the western United States. Such methods are based on the estimation of the depth to the bottom of magnetic sources, which is assumed to correspond to the temperature at which rocks lose their spontaneous magnetization. In this study, we test and apply a method based on the spectral analysis of magnetic anomalies. Early spectral analysis methods assumed that crustal magnetization is a completely uncorrelated function of position. Our method incorporates a more realistic representation where magnetization has a fractal distribution defined by three independent parameters: the depths to the top and bottom of magnetic sources and a fractal parameter related to the geology. The predictions of this model are compatible with radial power spectra obtained from aeromagnetic data in the western United States. Model parameters are mapped by estimating their value within a sliding window swept over the study area. The method works well on synthetic data sets when one of the three parameters is specified in advance. The application of this method to western United States magnetic compilations, assuming a constant fractal parameter, allowed us to detect robust long-wavelength variations in the depth to the bottom of magnetic sources. Depending on the geologic and geophysical context, these features may result from variations in depth to the Curie temperature isotherm, depth to the mantle, depth to the base of volcanic rocks, or geologic settings that affect the value of the fractal parameter. Depth to the bottom of magnetic sources shows several features correlated with prominent heat flow anomalies. It also shows some features absent in the map of heat flow. Independent geophysical and geologic data sets are examined to determine their origin, thereby providing new insights on the thermal and geologic crustal structure of the western United States.

  2. Object-based neglect in number processing

    PubMed Central

    2013-01-01

    Recent evidence suggests that neglect patients seem to have particular problems representing relatively smaller numbers corresponding to the left part of the mental number line. However, while this indicates space-based neglect for representational number space little is known about whether and - if so - how object-based neglect influences number processing. To evaluate influences of object-based neglect in numerical cognition, a group of neglect patients and two control groups had to compare two-digit numbers to an internally represented standard. Conceptualizing two-digit numbers as objects of which the left part (i.e., the tens digit should be specifically neglected) we were able to evaluate object-based neglect for number magnitude processing. Object-based neglect was indicated by a larger unit-decade compatibility effect actually reflecting impaired processing of the leftward tens digits. Additionally, faster processing of within- as compared to between-decade items provided further evidence suggesting particular difficulties in integrating tens and units into the place-value structure of the Arabic number system. In summary, the present study indicates that, in addition to the spatial representation of number magnitude, also the processing of place-value information of multi-digit numbers seems specifically impaired in neglect patients. PMID:23343126

  3. Water resource use and management by the United States forest products industry.

    PubMed

    Wiegand, P S; Flinders, C A; Ice, G G; Malmberg, B J; Fisher, R P

    2009-01-01

    The connections between forest products operations and water resources in the United States is considered and, where possible, quantified. Manufacture of wood, pulp, and paper products and the influences of forest management and forest products manufacture on water quality are discussed. Most fresh water in the US originates in forested areas. Responsible harvesting strategies, best management practices, and forest re-growth combine to minimize or eliminate changes in water availability and degradation of water quality due to harvesting. Relative to alternative land uses and large-scale disturbance events, forested areas produce the highest quality of fresh water. Water inputs for the manufacture of forest products total about 5.8 billion m(3) per year, an amount equal about 0.4% of the surface and groundwater yield from timberland. Approximately 88% of water used in manufacturing is treated and returned directly to surface waters, about 11% is converted to water vapor and released during the manufacturing process, and 1% is imparted to products or solid residuals. Extensive study and continued monitoring of treated effluents suggest few or no concerns regarding the compatibility of current effluents with healthy aquatic systems.

  4. Critical Value Reporting in Transfusion Medicine

    PubMed Central

    Reese, Erika M.; Nelson, Randin C.; Flegel, Willy A.; Byrne, Karen M.; Booth, Garrett S.

    2017-01-01

    Abstract Objectives: While critical value procedures have been adopted in most areas of the clinical laboratory, their use in transfusion medicine has not been reviewed in detail. The results of this study present a comprehensive overview of critical value reporting and communication practices in transfusion medicine in the United States. Methods: A web-based survey was developed to collect data on the prevalence of critical value procedures and practices of communicating results. The survey was distributed via email to US hospital-based blood banks. Results: Of 123 facilities surveyed, 84 (68.3%) blood banks had a critical value procedure. From a panel of 23 common blood bank results, nine results were selected by more than 70% of facilities as either a critical value or requiring rapid communication as defined by an alternate procedure. Conclusions: There was overlap among results communicated by facilities with and without a critical value procedure. The most frequently communicated results, such as incompatible crossmatch for RBC units issued uncrossmatched, delay in finding compatible blood due to a clinically significant antibody, and transfusion reaction evaluation suggestive of a serious adverse event, addressed scenarios associated with the leading reported causes of transfusion-related fatalities. PMID:28371931

  5. Weighted Geometric Dilution of Precision Calculations with Matrix Multiplication

    PubMed Central

    Chen, Chien-Sheng

    2015-01-01

    To enhance the performance of location estimation in wireless positioning systems, the geometric dilution of precision (GDOP) is widely used as a criterion for selecting measurement units. Since GDOP represents the geometric effect on the relationship between measurement error and positioning determination error, the smallest GDOP of the measurement unit subset is usually chosen for positioning. The conventional GDOP calculation using matrix inversion method requires many operations. Because more and more measurement units can be chosen nowadays, an efficient calculation should be designed to decrease the complexity. Since the performance of each measurement unit is different, the weighted GDOP (WGDOP), instead of GDOP, is used to select the measurement units to improve the accuracy of location. To calculate WGDOP effectively and efficiently, the closed-form solution for WGDOP calculation is proposed when more than four measurements are available. In this paper, an efficient WGDOP calculation method applying matrix multiplication that is easy for hardware implementation is proposed. In addition, the proposed method can be used when more than exactly four measurements are available. Even when using all-in-view method for positioning, the proposed method still can reduce the computational overhead. The proposed WGDOP methods with less computation are compatible with global positioning system (GPS), wireless sensor networks (WSN) and cellular communication systems. PMID:25569755

  6. JOCG Aircraft/Stores Compatibility Symposium Proceedings (8th) Held in Fort Walton Beach, Florida on 23-25 October 1990

    DTIC Science & Technology

    1990-10-25

    Compatibility Sub- Group Steering Committee Sub- Group Chairman Wiley I. Robinson Air Force Systems Command Study Group Chairmen Electrical Interface Joe...on the surface of the body organized into groups defining the corners of a series of four -sided surface panel elements which represent a faceted...Structures Technology. In the Aeroanalysis Group , Dr. Cunningham has conducted many studies leading to devel- opments in the area of analytically

  7. L Band Service Compatibility : Part II: Optimum GPS Receiver ABI Compatibility

    DOT National Transportation Integrated Search

    2015-03-12

    Workshop Objectives. This is the Second of Two Parts on Compatibility. Last time, OOBE. Today examine mitigation of Adjacent Band Interference, ABI. Apply Relevant TWG and NPEF (2011) data to engage compatibility analysis. Assert Principle: Dr. Brad ...

  8. Chemical Retraction Agents - in vivo and in vitro Studies into their Physico-Chemical Properties, Biocompatibility with Gingival Margin Tissues and Compatibility with Elastomer Impression Materials.

    PubMed

    Nowakowska, Danuta; Saczko, Jolanta; Kulbacka, Julita; Wicckiewicz, Wlodzimierz

    2017-01-01

    Gingival margin retraction/displacement (GMR/D) is a commonly accepted procedure in restorative dentistry. Of the various retraction methods, the chemo-mechanical approach with retraction media and chemical retraction agents (ChRAs) is mostly used. Different local and/or systemic side effects were observed after "chemical attacks" from these retraction agents. Moreover, no consensus exists as to the compatibility of chemical agents with different impression materials. This paper reports the findings of in vivo and in vitro studies and we discuss the physico-chemical properties of chemical retraction agents, their undesirable clinical side effects, biological activity and compatibility with selected groups of elastomer impression materials. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  9. A study on contraction of pneumatic artificial muscle (PAM) for load-lifting

    NASA Astrophysics Data System (ADS)

    Najmuddin, W. S. W. A.; Mustaffa, M. T.

    2017-10-01

    Pneumatic Artificial Muscles (PAMs) have been known for its wide application in various aspects of industrial automation and robotic equipments. Many advantages in terms of high power-to-volume ratio, high power-to-weight ratio, stick-slip-free operation and high degree of safety offer by PAM compare to traditional actuators. However, behind this benefits lie a limitation of significant compatibility of PAM mechanism which have to be considered so as to fully understand how the PAM works during load-lifting. In this study, the mesh suitability experiment and the effect of force load on PAM contraction experiment have been carried out. PAM is constructed and compatibility of bladder and the braided mesh to produce uniform expansion is investigated. Moreover, the first experimental result of finding compatibility is used to verify the contraction value under various loads.

  10. Space construction system analysis study: Project systems and missions descriptions

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Three project systems are defined and summarized. The systems are: (1) a Solar Power Satellite (SPS) Development Flight Test Vehicle configured for fabrication and compatible with solar electric propulsion orbit transfer; (2) an Advanced Communications Platform configured for space fabrication and compatible with low thrust chemical orbit transfer propulsion; and (3) the same Platform, configured to be space erectable but still compatible with low thrust chemical orbit transfer propulsion. These project systems are intended to serve as configuration models for use in detailed analyses of space construction techniques and processes. They represent feasible concepts for real projects; real in the sense that they are realistic contenders on the list of candidate missions currently projected for the national space program. Thus, they represent reasonable configurations upon which to base early studies of alternative space construction processes.

  11. Monosaccharides as Versatile Units for Water-Soluble Supramolecular Polymers.

    PubMed

    Leenders, Christianus M A; Jansen, Gijs; Frissen, Martijn M M; Lafleur, René P M; Voets, Ilja K; Palmans, Anja R A; Meijer, E W

    2016-03-18

    We introduce monosaccharides as versatile water-soluble units to compatibilise supramolecular polymers based on the benzene-1,3,5-tricarboxamide (BTA) moiety with water. A library of monosaccharide-based BTAs is evaluated, varying the length of the alkyl chain (hexyl, octyl, decyl and dodecyl) separating the BTA and saccharide units, as well as the saccharide units (α-glucose, β-glucose, α-mannose and α-galactose). In all cases, the monosaccharides impart excellent water compatibility. The length of the alkyl chain is the determining factor to obtain either long, one-dimensional supramolecular polymers (dodecyl spacer), small aggregates (decyl spacer) or molecularly dissolved (octyl and hexyl) BTAs in water. For the BTAs comprising a dodecyl spacer, our results suggest that a cooperative self-assembly process is operative and that the introduction of different monosaccharides does not significantly change the self- assembly behaviour. Finally, we investigate the potential of post-assembly functionalisation of the formed supramolecular polymers by taking advantage of dynamic covalent bond formation between the monosaccharides and benzoxaboroles. We observe that the supramolecular polymers readily react with a fluorescent benzoxaborole derivative permitting imaging of these dynamic complexes by confocal fluorescence microscopy. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. A METHOD FOR DETERMINING THE COMPATIBILITY OF HAZARDOUS WASTES

    EPA Science Inventory

    This report describes a method for determining the compatibility of the binary combinations of hazardous wastes. The method consists of two main parts, namely: (1) the step-by-step compatibility analysis procedures, and (2) the hazardous wastes compatibility chart. The key elemen...

  13. Greek-Cypriot Teachers' Perceptions of Religious Education and Its Contribution to Peace: Perspectives of (In)compatibility in a Divided Society

    ERIC Educational Resources Information Center

    Loukaidis, Loizos; Zembylas, Michalinos

    2017-01-01

    This paper explores the ways in which a group of primary school teachers in Cyprus interprets religious education and its contribution to peace. In particular, this phenomenological exploratory study: first, examines how teachers perceive religious education and whether this conceptualization is considered to be (in)compatible with peace in the…

  14. The Compatibility of Developed Mathematics Textbooks' Content in Saudi Arabia (Grades 6-8) with NCTM Standards

    ERIC Educational Resources Information Center

    Alshehri, Mohammed Ali; Ali, Hassan Shawki

    2016-01-01

    This study aimed to investigate the compatibility of developed mathematics textbooks' content (grades 6-8) in Saudi Arabia with NCTM standards in the areas of: number and operations, algebra, geometry, measurement, data analysis and probability. To achieve that goal, a list of (NCTM) standards for grades (6-8) were translated to Arabic language,…

  15. Could We Make Diverse Learning Materials Compatible with E-Readers Used in Classroom Learning Settings?

    ERIC Educational Resources Information Center

    Young, Shelley Shwu-Ching; Lin, Wei-Lin

    2012-01-01

    This study explores how to make diverse learning/instructional materials compatible with e-readers when the instructor pioneered to adopt e-readers into a course of the graduate level. What problems did the instructor encounter when she used the e-readers as a major tool to deliver learning contents, such as the process of converting the…

  16. Utility of the 3Di Short Version for the Diagnostic Assessment of Autism Spectrum Disorder and Compatibility with DSM-5

    ERIC Educational Resources Information Center

    Slappendel, Geerte; Mandy, William; van der Ende, Jan; Verhulst, Frank C.; van der Sijde, Ad; Duvekot, Jorieke; Skuse, David; Greaves-Lord, Kirstin

    2016-01-01

    The Developmental Diagnostic Dimensional Interview-short version (3Di-sv) provides a brief standardized parental interview for diagnosing autism spectrum disorder (ASD). This study explored its validity, and compatibility with DSM-5 ASD. 3Di-sv classifications showed good sensitivity but low specificity when compared to ADOS-2-confirmed clinical…

  17. Mirror neuron activation as a function of explicit learning: changes in mu-event-related power after learning novel responses to ideomotor compatible, partially compatible, and non-compatible stimuli.

    PubMed

    Behmer, Lawrence P; Fournier, Lisa R

    2016-11-01

    Questions regarding the malleability of the mirror neuron system (MNS) continue to be debated. MNS activation has been reported when people observe another person performing biological goal-directed behaviors, such as grasping a cup. These findings support the importance of mapping goal-directed biological behavior onto one's motor repertoire as a means of understanding the actions of others. Still, other evidence supports the Associative Sequence Learning (ASL) model which predicts that the MNS responds to a variety of stimuli after sensorimotor learning, not simply biological behavior. MNS activity develops as a consequence of developing stimulus-response associations between a stimulus and its motor outcome. Findings from the ideomotor literature indicate that stimuli that are more ideomotor compatible with a response are accompanied by an increase in response activation compared to less compatible stimuli; however, non-compatible stimuli robustly activate a constituent response after sensorimotor learning. Here, we measured changes in the mu-rhythm, an EEG marker thought to index MNS activity, predicting that stimuli that differ along dimensions of ideomotor compatibility should show changes in mirror neuron activation as participants learn the respective stimulus-response associations. We observed robust mu-suppression for ideomotor-compatible hand actions and partially compatible dot animations prior to learning; however, compatible stimuli showed greater mu-suppression than partially or non-compatible stimuli after explicit learning. Additionally, non-compatible abstract stimuli exceeded baseline only after participants explicitly learned the motor responses associated with the stimuli. We conclude that the empirical differences between the biological and ASL accounts of the MNS can be explained by Ideomotor Theory. © 2016 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  18. Lesson plan profile of senior high school biology teachers in Subang

    NASA Astrophysics Data System (ADS)

    Rohayati, E.; Diana, S. W.; Priyandoko, D.

    2018-05-01

    Lesson plan have important role for biology teachers in teaching and learning process. The aim of this study was intended to gain an overview of lesson plan of biology teachers’ at Senior High Schools in Subang which were the members of biology teachers association in Subang. The research method was descriptive method. Data was collected from 30 biology teachers. The result of study showed that lesson plan profile in terms of subject’s identity had good category with 83.33 % of average score. Analysis on basic competence in fair category with 74.45 % of average score. The compatibility of method/strategy was in fair category with average score 72.22 %. The compatibility of instrument, media, and learning resources in fair category with 71.11 % of average score. Learning scenario was in good category with 77.00 % of average score. The compatibility of evaluation was in low category with 56.39 % of average score. It can be concluded that biology teachers in Subang were good enough in making lesson plan, however in terms of the compatibility of evaluation needed to be fixed. Furthermore, teachers’ training for biology teachers’ association was recommended to increasing teachers’ skill to be professional teachers.

  19. The quality of social relationships in ravens

    PubMed Central

    Fraser, Orlaith N.; Bugnyar, Thomas

    2015-01-01

    The quality of a social relationship represents the history of past social interactions between two individuals, from which the nature and outcome of future interactions can be predicted. Current theory predicts that relationship quality comprises three separate components, its value, compatibility and security. This study is the first to investigate the components of relationship quality in a large-brained bird. Following methods recently used to obtain quantitative measures of each relationship quality component in chimpanzees, Pan troglodytes, we entered data on seven behavioural variables from a group of 11 ravens, Corvus corax, into a principal components analysis. The characteristics of the extracted components matched those predicted for value, compatibility and security, and were labelled as such. When the effects of kinship and sex combination on each relationship quality component were analysed, we found that kin had more valuable relationships, whereas females had less secure and compatible relationships, although the effect of sex combination on compatibility only applied to nonkin. These patterns are consistent with what little knowledge we have of raven relationships from aviary studies and show that the components of relationship quality in ravens may indeed be analogous to those in chimpanzees. PMID:25821236

  20. Permanganate gel (PG) for groundwater remediation: compatibility, gelation, and release characteristics.

    PubMed

    Lee, Eung Seok; Olson, Pamela R; Gupta, Neha; Solpuker, Utku; Schwartz, Franklin W; Kim, Yongje

    2014-02-01

    Permanganate (MnO4(-)) is a strong oxidant that is widely used for treating chlorinated ethylenes in groundwater. This study aims to develop hyper-saline MnO4(-) solution (MnO4(-) gel; PG) that can be injected into aquifers via wells, slowly gelates over time, and slowly release MnO4(-) to flowing water. In this study, compatibility and miscibility of gels, such as chitosan, aluminosilicate, silicate, and colloidal silica gels, with MnO4(-) were tested. Of these gels, chitosan was reactive with MnO4(-). Aluminosilicates were compatible but not readily miscible with MnO4(-). Silicates and colloidal silica were both compatible and miscible with MnO4(-), and gelated with addition of KMnO4 granules. Colloidal silica has low initial viscosity (<15cP), exhibited delayed gelation characteristics with the lag times ranging from 0 to 200min. Release of MnO4(-) from the colloidal silica-based PG gel occurred in a delayed fashion, with maximum duration of 24h. These results suggested that colloidal silica can be used to create PG or delayed-gelling forms containing other oxidants which can be used for groundwater remediation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Studies of material and process compatibility in developing compact silicon vapor chambers

    NASA Astrophysics Data System (ADS)

    Cai, Qingjun; Bhunia, Avijit; Tsai, Chialun; Kendig, Martin W.; DeNatale, Jeffrey F.

    2013-06-01

    The performance and long-term reliability of a silicon vapor chamber (SVC) developed for thermal management of high-power electronics critically depend on compatibility of the component materials. A hermetically sealed SVC presented in this paper is composed of bulk silicon, glass-frit as a bonding agent, lead/tin solder as an interface sealant and a copper charging tube. These materials, in the presence of a water/vapor environment, may chemically react and release noncondensable gas (NCG), which can weaken structural strength and degrade the heat transfer performance with time. The present work reports detailed studies on chemical compatibility of the components and potential solutions to avoid the resulting thermal performance degradation. Silicon surface oxidation and purification of operating liquid are necessary steps to reduce performance degradation in the transient period. A lead-based solder with its low reflow temperature is found to be electrochemically stable in water/vapor environment. High glazing temperature solidifies molecular bonding in glass-frit and mitigates PbO precipitation. Numerous liquid flushes guarantee removal of chemical residual after the charging tube is soldered to SVC. With these improvements on the SVC material and process compatibility, high effective thermal conductivity and steady heat transfer performance are obtained.

  2. Compatibility and infectivity of a Cercospora rodmanii formulation with enhancing agents. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pennington, J.C.; Theriot, E.A.

    1983-06-01

    A formulation of the fungus Cercospora rodmanii Conway has been produced, as a biocontrol of waterhyacinth (Eichhornia crassipes (Mart.) Solms.). To ensure the most efficient germination of the formulation, 12 potential enhancing agents were tested for addition during the spray application. The agents were aspartic acid, glucose, glutamic acid, gum xanthan, nutrient agar, Ortho X-77 Spreader, Tween 20, Tween 60, Tween 80, sodium alginate, Super Slupper, and yeast extract. Compatibility of test agents and combinations of test agents with two lots of the formulation was determined in the laboratory. All combinations of test agents were compatible with both lots ofmore » the C. rodmanii formulation. The C. rodmanii formulation was sprayed with test agents on waterhyacinth pseudolaminae. Damage was monitored each week for 8 weeks by assigning a disease index to each original and new pseudolaminae. No spots having characteristics suggestive of C. rodmanii infection were observed at any time during the study. Lack of infectivity could be remedied by isolating a virulent strain of C. rodmanii from the field. Agents determined to be compatible in this study could then be reexamined for enhancing infectivity on a virulent C. rodmanii formulation. 14 references, 2 figures, 5 tables.« less

  3. Deciphering the Theobroma cacao self-incompatibility system: from genomics to diagnostic markers for self-compatibility.

    PubMed

    Lanaud, Claire; Fouet, Olivier; Legavre, Thierry; Lopes, Uilson; Sounigo, Olivier; Eyango, Marie Claire; Mermaz, Benoit; Da Silva, Marcos Ramos; Loor Solorzano, Rey Gaston; Argout, Xavier; Gyapay, Gabor; Ebaiarrey, Herman Ebai; Colonges, Kelly; Sanier, Christine; Rivallan, Ronan; Mastin, Géraldine; Cryer, Nicholas; Boccara, Michel; Verdeil, Jean-Luc; Efombagn Mousseni, Ives Bruno; Peres Gramacho, Karina; Clément, Didier

    2017-10-13

    Cocoa self-compatibility is an important yield factor and has been described as being controlled by a late gameto-sporophytic system expressed only at the level of the embryo sac. It results in gametic non-fusion and involves several loci. In this work, we identified two loci, located on chromosomes 1 and 4 (CH1 and CH4), involved in cocoa self-incompatibility by two different processes. Both loci are responsible for gametic selection, but only one (the CH4 locus) is involved in the main fruit drop. The CH1 locus acts prior to the gamete fusion step and independently of the CH4 locus. Using fine-mapping and genome-wide association studies, we focused analyses on restricted regions and identified candidate genes. Some of them showed a differential expression between incompatible and compatible reactions. Immunolocalization experiments provided evidence of CH1 candidate genes expressed in ovule and style tissues. Highly polymorphic simple sequence repeat (SSR) diagnostic markers were designed in the CH4 region that had been identified by fine-mapping. They are characterized by a strong linkage disequilibrium with incompatibility alleles, thus allowing the development of efficient diagnostic markers predicting self-compatibility and fruit setting according to the presence of specific alleles or genotypes. SSR alleles specific to self-compatible Amelonado and Criollo varieties were also identified, thus allowing screening for self-compatible plants in cocoa populations. © The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  4. Brain-Compatible Learning: Principles and Applications in Athletic Training

    PubMed Central

    2003-01-01

    Objective: To discuss the principles of brain-compatible learning research and provide insights into how this research may be applied in athletic training education to benefit the profession. Background: In the past decade, new brain-imaging techniques have allowed us to observe the brain while it is learning. The field of neuroscience has produced a body of empirical data that provides a new understanding of how we learn. This body of data has implications in education, although the direct study of these implications is in its infancy. Description: An overview of how the brain learns at a cellular level is provided, followed by a discussion of the principles of brain-compatible learning. Applications of these principles and implications for the field of athletic training education are also offered. Application: Many educational-reform fads have garnered attention in the past. Brain-compatible learning will not likely be one of those, as its origin is in neuroscience, not education. Brain-compatible learning is not an educational-reform movement. It does not prescribe how to run your classroom or offer specific techniques to use. Rather, it provides empirical data about how the brain learns and suggests guidelines to be considered while preparing lessons for your students. These guidelines may be incorporated into every educational setting, with every type of curriculum and every age group. The field of athletic training lends itself well to many of the basic principles of brain-compatible learning. PMID:16558681

  5. Liquid oxygen LOX compatibility evaluations of aluminum lithium (Al-Li) alloys: Investigation of the Alcoa 2090 and MMC weldalite 049 alloys

    NASA Technical Reports Server (NTRS)

    Diwan, Ravinder M.

    1989-01-01

    The behavior of liquid oxygen (LOX) compatibility of aluminum lithium (Al-Li) alloys is investigated. Alloy systems of Alcoa 2090, vintages 1 to 3, and of Martin Marietta Corporation (MMC) Weldalite 049 were evaluated for their behavior related to the LOX compatibility employing liquid oxygen impact test conditions under ambient pressures and up to 1000 psi. The developments of these aluminum lithium alloys are of critical and significant interest because of their lower densities and higher specific strengths and improved mechanical properties at cryogenic temperatures. Of the different LOX impact tests carried out at the Marshall Space Flight Center (MSFC), it is seen that in certain test conditions at higher pressures, not all Al-Li alloys are LOX compatible. In case of any reactivity, it appears that lithium makes the material more sensitive at grain boundaries due to microstructural inhomogeneities and associated precipitate free zones (PFZ). The objectives were to identify and rationalize the microstructural mechanisms that could be relaxed to LOX compatibility behavior of the alloy system in consideration. The LOX compatibility behavior of Al-Li 2090 and Weldalite 049 is analyzed in detail using microstructural characterization techniques with light optical metallography, scanning electron microscopy (SEM), electron microprobe analysis, and surface studies using secondary ion mass spectrometry (SIMS), electron spectroscopy in chemical analysis (ESCA) and Auger electron spectroscopy (AES). Differences in the behavior of these aluminum lithium alloys are assessed and related to their chemistry, heat treatment conditions, and microstructural effects.

  6. The Catastrophe Revisited

    PubMed Central

    Ratner, Buddy D.

    2007-01-01

    The biomaterials community has been unable to accurately assign the term “blood compatible” to a biomaterial in spite of 50 years of intensive research on the subject. There is no clear consensus as to which materials are “blood compatible.” There are no standardized methods to assess blood compatibility. Since we use millions of devices in contact with blood each year, it is imperative we give serious thought to this intellectual catastrophe. In this perspective, I consider five hypotheses as to why progress has been slow in evolving a clear understanding of blood compatibility: Hypothesis 1 -- It is impossible to make a blood compatible material. Hypothesis 2 -- We do not understand the biology behind blood compatibility. Hypothesis 3 -- We do not understand how to test for or evaluate blood compatibility. Hypothesis 4 -- Certain materials of natural origin seem to show better blood compatibility but we do not know how to exploit this concept. Hypothesis 5 -- We now have better blood compatible materials but the regulatory and economic climate prevent adoption in clinical practice. PMID:17689608

  7. Crystalline imide/arylene ether copolymers

    NASA Technical Reports Server (NTRS)

    Jensen, Brian J. (Inventor); Hergenrother, Paul M. (Inventor); Bass, Robert G. (Inventor)

    1995-01-01

    Crystalline imide/arylene ether block copolymers are prepared by reacting anhydride terminated poly(amic acids) with amine terminated poly)arylene ethers) in polar aprotic solvents and chemically or thermally cyclodehydrating the resulting intermediate poly(amic acids). The block copolymers of the invention have one glass transition temperature or two, depending on the particular structure and/or the compatibility of the block units. Most of these crystalline block copolymers for tough, solvent resistant films with high tensile properties. While all of the copolymers produced by the present invention are crystalline, testing reveals that copolymers with longer imide blocks or higher imide content have increased crystallinity.

  8. Hardware Demonstration: Radiated Emissions as a Function of Common Mode Current

    NASA Technical Reports Server (NTRS)

    Mc Closkey, John; Roberts, Jen

    2016-01-01

    This presentation describes the electromagnetic compatibility (EMC) tests performed on the Integrated Science Instrument Module (ISIM), the science payload of the James Webb Space Telescope (JWST), at NASAs Goddard Space Flight Center (GSFC) in August 2015. By its very nature of being an integrated payload, it could be treated as neither a unit level test nor an integrated spacecraft observatory test. Non-standard test criteria are described along with non-standard test methods that had to be developed in order to evaluate them. Results are presented to demonstrate that all test criteria were met in less than the time allocated.

  9. Implementation of the VGM Graphics System on the PDP-11/50 under the RSX-11M Operating System and Construction of a Compatible Software Driver for the Ramtek RM-9400.

    DTIC Science & Technology

    1982-06-01

    no other. is the field of computer grapnIcs expanded, such limitations became a real liability. The inability to use one program at more tnan one...terms of these environmental factors. For example, some programs may be portable from one device to another as long as the computing environment is not...PemPOMMIN OROANI&ATIO NAMI AND A00RESS IQ. PROGRAM CLEMENT. PROJECT. TASK AREA a WORK UNiT muN9ERS Naval Postgraduate School Monterey, California 93940

  10. EMC Test Challenges for NASAs James Webb Space Telescope

    NASA Technical Reports Server (NTRS)

    McCloskey, John

    2016-01-01

    This presentation describes the electromagnetic compatibility (EMC) tests performed on the Integrated Science Instrument Module (ISIM), the science payload of the James Webb Space Telescope (JWST), at NASAs Goddard Space Flight Center (GSFC) in August 2015. By its very nature of being an integrated payload, it could be treated as neither a unit level test nor an integrated spacecraft observatory test. Non-standard test criteria are described along with non-standard test methods that had to be developed in order to evaluate them. Results are presented to demonstrate that all test criteria were met in less than the time allocated.

  11. EMC Test Challenges for NASA's James Webb Space Telescope

    NASA Technical Reports Server (NTRS)

    McCloskey, John

    2016-01-01

    This presentation describes the electromagnetic compatibility (EMC) tests performed on the Integrated Science Instrument Module (ISIM), the science payload of the James Webb Space Telescope (JWST), at NASAs Goddard Space Flight Center (GSFC) in August 2015. By its very nature of being an integrated payload, it could be treated as neither a unit level test nor an integrated spacecraft observatory test. Non-standard test criteria are described along with non-standard test methods that had to be developed in order to evaluate them. Results are presented to demonstrate that all test criteria were met in less than the time allocated.

  12. Detection of proteins on blot transfer membranes.

    PubMed

    Sasse, Joachim; Gallagher, Sean R

    2003-11-01

    In the basic and alternate protocols of this unit, proteins are stained after electroblotting from polyacrylamide gels to blot transfer membranes. If the samples of interest are electrophoresed in duplicate and transferred to a blot transfer membrane, half of the membrane can be stained to determine the efficiency of transfer to the membrane and the other half can be used for immunoblotting (i.e., western blotting). Detection limits of each staining method are given along with a list of compatible blot transfer membranes and gels. A support protocol describes a method for alkali treatment that enhances subsequent staining of bound proteins.

  13. Electronic delay ignition module for single bridgewire Apollo standard initiator

    NASA Technical Reports Server (NTRS)

    Ward, R. D.

    1975-01-01

    An engineering model and a qualification model of the EDIM were constructed and tested to Scout flight qualification criteria. The qualification model incorporated design improvements resulting from the engineering model tests. Compatibility with single bridgewire Apollo standard initiator (SBASI) was proven by test firing forty-five (45) SBASI's with worst case voltage and temperature conditions. The EDIM was successfully qualified for Scout flight application with no failures during testing of the qualification unit. Included is a method of implementing the EDIM into Scout vehicle hardware and the ground support equipment necessary to check out the system.

  14. Red blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management.

    PubMed

    Yazdanbakhsh, Karina; Ware, Russell E; Noizat-Pirenne, France

    2012-07-19

    Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious complications for the patient including life-threatening delayed hemolytic transfusion reactions and difficulty in finding compatible units, which can cause transfusion delays. In this review, we discuss the risk factors associated with alloimmunization with emphasis on possible mechanisms that can trigger delayed hemolytic transfusion reactions in sickle cell disease, and we describe the challenges in transfusion management of these patients, including opportunities and emerging approaches for minimizing this life-threatening complication.

  15. The CareFlight Stretcher Bridge: a compact mobile intensive care unit.

    PubMed

    Wishaw, K J; Munford, B J; Roby, H P

    1990-05-01

    A mobile intensive care module has been developed for aeromedical transport of the critical care patient. It incorporates monitoring, ventilator, oxygen and suction, and infusion pumps. The device clips to a lightweight stretcher, over the patient at hip to knee level. This system is compatible with nearly all patient transport vehicles and allows monitors to be run from vehicle power. An assessment of the system after more than 500 transports is that it represents a significant advance over systems used previously. The advantages and disadvantages of the system compared with unmounted or vehicle-mounted equipment are discussed.

  16. Direct, rapid, and label-free detection of enzyme-substrate interactions in physiological buffers using CMOS-compatible nanoribbon sensors.

    PubMed

    Mu, Luye; Droujinine, Ilia A; Rajan, Nitin K; Sawtelle, Sonya D; Reed, Mark A

    2014-09-10

    We demonstrate the versatility of Al2O3-passivated Si nanowire devices ("nanoribbons") in the analysis of enzyme-substrate interactions via the monitoring of pH change. Our approach is shown to be effective through the detection of urea in phosphate buffered saline (PBS), and penicillinase in PBS and urine, at limits of detection of <200 μM and 0.02 units/mL, respectively. The ability to extract accurate enzyme kinetics and the Michaelis-Menten constant (Km) from the acetylcholine-acetylcholinesterase reaction is also demonstrated.

  17. Specifications for and preliminary design of a plant growth chamber for orbital experimental experiments

    NASA Technical Reports Server (NTRS)

    Sweet, H. C.; Simmonds, R. C.

    1976-01-01

    It was proposed that plant experiments be performed on board the space shuttle. To permit the proper execution of most tests, the craft must contain a plant growth chamber which is adequately designed to control those environmental factors which can induce changes in a plant's physiology and morphology. The various needs of, and environmental factors affecting, plants are identified. The permissilbe design, construction and performance limits for a plant-growth chamber are set, and tentative designs were prepared for units which are compatible with both the botanical requirements and the constraints imposed by the space shuttle.

  18. The solubilization of fatty acids in systems based on block copolymers and nonionic surfactants

    NASA Astrophysics Data System (ADS)

    Mirgorodskaya, A. B.; Yatskevich, E. I.; Zakharova, L. Ya.

    2010-12-01

    The solubilizing action of micellar, microemulsion, and polymer-colloid systems formed on the basis of biologically compatible amphiphilic polymers and nonionic surfactants on capric, lauric, palmitic, and stearic acids was characterized quantitatively. Systems based on micelle forming oxyethyl compounds increased the solubility of fatty acids by more than an order of magnitude. Acid molecules incorporated into micelles increased their size and caused structural changes. Solubilization was accompanied by complete or partial destruction of intrinsic acid associates and an increase in their p K a by 1.5-2 units compared with water.

  19. Automated selection of synthetic biology parts for genetic regulatory networks.

    PubMed

    Yaman, Fusun; Bhatia, Swapnil; Adler, Aaron; Densmore, Douglas; Beal, Jacob

    2012-08-17

    Raising the level of abstraction for synthetic biology design requires solving several challenging problems, including mapping abstract designs to DNA sequences. In this paper we present the first formalism and algorithms to address this problem. The key steps of this transformation are feature matching, signal matching, and part matching. Feature matching ensures that the mapping satisfies the regulatory relationships in the abstract design. Signal matching ensures that the expression levels of functional units are compatible. Finally, part matching finds a DNA part sequence that can implement the design. Our software tool MatchMaker implements these three steps.

  20. Microbial identification system for Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Brown, Harlan D.; Scarlett, Janie B.; Skweres, Joyce A.; Fortune, Russell L.; Staples, John L.; Pierson, Duane L.

    1989-01-01

    The Environmental Health System (EHS) and Health Maintenance Facility (HMF) on Space Station Freedom will require a comprehensive microbiology capability. This requirement entails the development of an automated system to perform microbial identifications on isolates from a variety of environmental and clinical sources and, when required, to perform antimicrobial sensitivity testing. The unit currently undergoing development and testing is the Automated Microbiology System II (AMS II) built by Vitek Systems, Inc. The AMS II has successfully completed 12 months of laboratory testing and evaluation for compatibility with microgravity operation. The AMS II is a promising technology for use on Space Station Freedom.

  1. EMC tests on the RITA Ion Propulsion Assembly for the ARTEMIS satellite

    NASA Astrophysics Data System (ADS)

    Mueller, H.; Kukies, R.; Bassner, H.

    1992-07-01

    Objectives and results of EMC tests performed on the RITA Ion Propulsion Assembly to demonstrate its compatibility with the requirements of ARTEMIS are discussed. The tested configuration included the RIT 10 thruster, neutralizer, RF generator, power supply and control unit, and electrical ground support equipment. Test results show that the RIT 10 thruster fulfils the EMC requirements for radiated emission in the critical frequency ranges (L/S/KU bands). The emitted E- and H-fields are not expected to disturb the satellite electronics, and no special shielding or other measures to protect the antennas are needed.

  2. Apollo Soyuz test project. USA-USSR, fact sheet

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The Apollo Soyuz Test Project (ASTP) is discussed. The United States and the Soviet Union have agreed to develop compatible rendezvous and docking systems which will provide a basis for docking and rescue on future spacecraft of both nations. The ASTP mission will include testing the rendezvous system in orbit, verifying techniques for transfer of astronauts and cosmonauts, and conducting experiments while docked and undocked. Diagrams of the spacecraft and systems involved in the tests are presented. The prime contractors for the equipment are identified. Biographical data on the astronauts participating in the program are provided.

  3. An environmental dose experiment

    NASA Astrophysics Data System (ADS)

    Peralta, Luis

    2017-11-01

    Several radiation sources worldwide contribute to the delivered dose to the human population. This radiation also acts as a natural background when detecting radiation, for instance from radioactive sources. In this work a medium-sized plastic scintillation detector is used to evaluate the dose delivered by natural radiation sources. Calibration of the detector involved the use of radioactive sources and Monte Carlo simulation of the energy deposition per disintegration. A measurement of the annual dose due to background radiation to the body was then estimated. A dose value compatible with the value reported by the United Nations Scientific Committee on the Effects of Atomic Radiation was obtained.

  4. Nucleoside-O-Methyl-(H)-Phosphinates: Novel Monomers for the Synthesis of Methylphosphonate Oligonucleotides Using H-Phosphonate Chemistry.

    PubMed

    Kostov, Ondřej; Páv, Ondřej; Rosenberg, Ivan

    2017-09-18

    This unit comprises the straightforward synthesis of protected 2'-deoxyribonucleoside-O-methyl-(H)-phosphinates in both 3'- and 5'-series. These compounds represent a new class of monomers compatible with the solid-phase synthesis of oligonucleotides using H-phosphonate chemistry and are suitable for the preparation of both 3'- and 5'-O-methylphosphonate oligonucleotides. The synthesis of 4-toluenesulfonyloxymethyl-(H)-phosphinic acid as a new reagent for the preparation of O-methyl-(H)-phosphinic acid derivatives is described. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

  5. 1998 Conference on Precision Electromagnetic Measurements Digest. Proceedings.

    NASA Astrophysics Data System (ADS)

    Nelson, T. L.

    The following topics were dealt with: fundamental constants; caesium standards; AC-DC transfer; impedance measurement; length measurement; units; statistics; cryogenic resonators; time transfer; QED; resistance scaling and bridges; mass measurement; atomic fountains and clocks; single electron transport; Newtonian constant of gravitation; stabilised lasers and frequency measurements; cryogenic current comparators; optical frequency standards; high voltage devices and systems; international compatibility; magnetic measurement; precision power measurement; high resolution spectroscopy; DC transport standards; waveform acquisition and analysis; ion trap standards; optical metrology; quantised Hall effect; Josephson array comparisons; signal generation and measurement; Avogadro constant; microwave networks; wideband power standards; antennas, fields and EMC; quantum-based standards.

  6. Inheritance of graft compatibility in Douglas fir.

    Treesearch

    D.L. Copes

    1973-01-01

    Graft compatibility of genetically related and unrelated rootstock-scion combinations was compared. Scion clones were 75% compatible when grafted on half-related rootstocks but only 56% compatible when grafted on unrelated rootstocks. Most variance associated with graft incompatibility in Douglas-fir appears to be caused by multiple genes.

  7. Investigating Climate Compatible Development Outcomes and their Implications for Distributive Justice: Evidence from Malawi

    NASA Astrophysics Data System (ADS)

    Wood, Benjamin T.; Quinn, Claire H.; Stringer, Lindsay C.; Dougill, Andrew J.

    2017-09-01

    Governments and donors are investing in climate compatible development in order to reduce climate and development vulnerabilities. However, the rate at which climate compatible development is being operationalised has outpaced academic enquiry into the concept. Interventions aiming to achieve climate compatible development "wins" (for development, mitigation, adaptation) can also create negative side-effects. Moreover, benefits and negative side-effects may differ across time and space and have diverse consequences for individuals and groups. Assessments of the full range of outcomes created by climate compatible development projects and their implications for distributive justice are scarce. This article develops a framework using a systematic literature review that enables holistic climate compatible development outcome evaluation over seven parameters identified. Thereafter, we explore the outcomes of two donor-funded projects that pursue climate compatible development triple-wins in Malawi using this framework. Household surveys, semi-structured interviews and documentary material are analysed. Results reveal that uneven outcomes are experienced between stakeholder groups and change over time. Although climate compatible development triple-wins can be achieved through projects, they do not represent the full range of outcomes. Ecosystem—and community-based activities are becoming popularised as approaches for achieving climate compatible development goals. However, findings suggest that a strengthened evidence base is required to ensure that these approaches are able to meet climate compatible development goals and further distributive justice.

  8. Transfer of learning in choice reactions: The roles of stimulus type, response mode, and set-level compatibility.

    PubMed

    Yamaguchi, Motonori; Chen, Jing; Proctor, Robert W

    2015-08-01

    The Simon effect refers to the advantage of responding to spatially compatible stimuli. This effect can be eliminated or even reversed to favor spatially incompatible stimuli after participants practice a choice-reaction task with spatially incompatible mappings (e.g., pressing left and right keys to stimuli on the right and left, respectively). This transfer of incompatible spatial associations has been observed under conditions in which responses were made manually (e.g., keypresses, moving a joystick). The present study used vocal responses to reveal the primary determinants of the transfer effect, dissociating the influences of stimulus type, response mode, and their interaction (set-level compatibility). The results suggest that contextual match between the practice and transfer tasks with respect to stimulus type and response mode determined transfer of incompatible associations to the Simon task, and stimulus type determined the efficiency of acquiring new associations. However, there was little evidence that set-level compatibility plays any major role in either acquisition or transfer of spatial associations.

  9. Influences of layer thickness on the compatibility and physical properties of polycarbonate/polystyrene multilayered film via nanolayer coextrusion

    NASA Astrophysics Data System (ADS)

    Cheng, Junfeng; Chen, Zhiru; Zhou, Jiaqi; Cao, Zheng; Wu, Dun; Liu, Chunlin; Pu, Hongting

    2018-05-01

    The effects of layer thickness on the compatibility between polycarbonate (PC) and polystyrene (PS) and physical properties of PC/PS multilayered film via nanolayer coextrusion are studied. The morphology of multilayered structure is observed using a scanning electron microscope. This multilayered structure may have a negative impact on the transparency, but it can improve the water resistance and heat resistance of film. To characterize the compatibility between PC and PS, differential scanning calorimetry is used to measure the glass transition temperature. The compatibility is found to be improved with the decrease of layer thickness. Therefore, the viscosity of multilayered film is also reduced with the decrease of layer thickness. In addition, the multilayered structure can improve the tensile strength with the increase of layer numbers. Because of the complete and continuous layer structure of PC, the PC/PS multilayered film can retain its mechanical strength at the temperature above Tg of PS.

  10. Vapor Hydrogen Peroxide Sterilization Certification

    NASA Astrophysics Data System (ADS)

    Chen, Fei; Chung, Shirley; Barengoltz, Jack

    For interplanetary missions landing on a planet of potential biological interest, United States NASA planetary protection currently requires that the flight system must be assembled, tested and ultimately launched with the intent of minimizing the bioload taken to and deposited on the planet. Currently the only NASA approved microbial reduction method is dry heat sterilization process. However, with utilization of such elements as highly sophisticated electronics and sensors in modern spacecraft, this process presents significant materials challenges and is thus an undesirable bioburden reduction method to design engineers. The objective of this work is to introduce vapor hydrogen peroxide (VHP) as an alternative to dry heat microbial reduction to meet planetary protection requirements. The VHP sterilization technology is widely used by the medical industry, but high doses of VHP may degrade the performance of flight hardware, or compromise material compatibility. The goal of our study is determine the minimum VHP process conditions for PP acceptable microbial reduction levels. A series of experiments were conducted using Geobacillus stearothermophilus to determine VHP process parameters that provided significant reductions in spore viability while allowing survival of sufficient spores for statistically significant enumeration. In addition to the obvious process parameters -hydrogen peroxide concentration, number of pulses, and exposure duration -the investigation also considered the possible effect of environmental pa-rameters. Temperature, relative humidity, and material substrate effects on lethality were also studied. Based on the results, a most conservative D value was recommended. This recom-mended D value was also validated using VHP "hardy" strains that were isolated from clean-rooms and environmental populations collected from spacecraft relevant areas. The efficiency of VHP at ambient condition as well as VHP material compatibility will also be presented.

  11. Virus-induced gene silencing suggests (1,3;1,4)-β-glucanase is a susceptibility factor in the compatible russian wheat aphid-wheat interaction.

    PubMed

    Anderson, Victoria A; Haley, Scott D; Peairs, Frank B; van Eck, Leon; Leach, Jan E; Lapitan, Nora L V

    2014-09-01

    The Russian wheat aphid (RWA), Diuraphis noxia (Kurdjumov), is a significant insect pest of wheat (Triticum aestivum L.) and has a major economic impact worldwide, especially on winter wheat in the western United States. The continuing emergence of new RWA biotypes virulent to existing resistance genes reinforces the need for more durable resistance. Studies have indicated that resistance in previously susceptible plants can be produced by knock-down of susceptibility genes or other genes involved in host plant susceptibility. Therefore, investigation into genes involved in compatible RWA-wheat interactions could be a feasible approach to achieving durable RWA resistance. The objective of this study was to test whether silencing (1,3;1,4)-β-glucanase, previously observed to be highly induced in susceptible compared with resistant wheat during aphid infestation, would confer resistance to a susceptible wheat genotype. Barley stripe mosaic virus-mediated virus-induced gene silencing was employed to test whether (1,3;1,4)-β-glucanase is involved in the susceptible reaction of 'Gamtoos-S' (GS). Controlled infestation with U.S. biotype RWA2 was done to assess aphid reproduction and host symptom development. Aphids on (1,3;1,4)-β-glucanase-silenced plants reproduced less per day and had longer prenymphipositional periods than those on control GS plants. Furthermore, the (1,3;1,4)-β-glucanase-silenced plants exhibited less chlorosis and greater dry weight compared with GS. Aphid reproduction and host plant symptom development showed linear relationships with (1,3;1,4)-β-glucanase transcript levels. Our results suggest that (1,3;1,4)-β-glucanase is required for successful infestation by the RWA and may be a susceptibility factor that could be exploited as a potential target for RWA resistance breeding.

  12. Metamorphic and tectonic evolution of Ceuta peninsula (Internal Rif): new interpretation in the framework of arc and back arc evolution

    NASA Astrophysics Data System (ADS)

    Homonnay, Emmanuelle; Lardeaux, Jean-Marc; Corsini, Michel; Cenki-Tok, Bénédicte; Bosch, Delphine; Munch, Philippe; Romagny, Adrien; Ouazzani-Touhami, Mohamed

    2016-04-01

    In the last twenty years, various geophysical investigations have established that the Western Mediterranean opened in a subduction context as a back arc domain. In the Alboran basin the dip of the subduction plane is eastwards or southeastwards depending of considered models. If the geological records of back-arc opening are well-known, the arc-related tectonic and petrologic evolutions are still poorly documented. In order to decipher these markers, we focalised structural, petrological and thermo-chronological studies on the Ceuta peninsula located in the Rif belt, on the western part of the Gibraltar arc to the North of Morocco. The present-day tectonic pile is constituted by: (1) the upper Ceuta unit, composed of High Pressure and High Temperature metapelites retromorphosed under Amphibolite-facies condition, with Ultra-High Pressure relicts, and pyrigarnite and spinel bearing peridotites boudins at its base, (2) the lower Monte Hacho unit, with orthogneisses metamorphosed under Amphibolite-facies conditions. Structural analysis indicates a polyphase tectonic evolution: (1) an earlier deformation phase only observed in the UHP metapelites and characterized by a steep S1 foliation plane, (2) a main deformation phase associated to a pervasive gently dipping S2 foliation plane bearing a L2 stretching lineation and synschistose folds whose axes are parallel to L2 and (3) a late deformation phase which developed S3 foliation plane and L3 stretching lineation coeval with development of narrow normal ductile shear zones. A zone of increasing deformation, several dozen meters wide, is identified as a major ductile shear zone involving the peridotitic lenses at the base of the metapelites of the Ceuta unit and overlaying this upper unit on top of the orthogneisses of the Monte Hacho lower unit. The attitude of mylonitic foliation and stretching and mineral lineations as well as the numerous shear sense indicators observed in the shear zone are consistent with a thrusting toward the NE. Furthermore, biotite-sillimanite bearing S2 foliation affecting the whole of crustal rocks is contemporaneous with the movement on this main ductile thrusting. We combined garnet-biotite and GASP thermo-barometers with thermodynamic modelling (Theriak-Domino) in order to constrain pressure and temperature conditions of D2 and D3 tectono-metamorphic events. P-T conditions of D2 deformation are in the range 7-10kbar and 770-820°C and are compatible with syn-tectonic partial melting. D3 deformation event occurred at 1-7kbar and 400-550°C. These metamorphic conditions reflect abnormally high geothermal gradients during both shortening and thinning and are clearly compatible with the thermal evolution recognized in continental arcs. Preliminary U-Th-Pb (monazite, zircon and xenotime) and previous Ar39/Ar40 (micas) analyses, furnished similar ages around 21 Ma for D2 and D3 events, suggesting a very fast transition from arc to back-arc dynamics.

  13. 46 CFR 150.150 - Exceptions to the compatibility chart.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Exceptions to the compatibility chart. 150.150 Section 150.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.150 Exceptions to the compatibility chart. The Commandant (G-MSO...

  14. 46 CFR Figure 1 to Part 150 - Compatibility Chart

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Compatibility Chart 1 Figure 1 to Part 150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES Pt. 150, Fig. 1 Figure 1 to Part 150—Compatibility Chart EC02FE91.079 ...

  15. 46 CFR Figure 1 to Part 150 - Compatibility Chart

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Compatibility Chart 1 Figure 1 to Part 150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES Pt. 150, Fig. 1 Figure 1 to Part 150—Compatibility Chart EC02FE91.079 ...

  16. 46 CFR Figure 1 to Part 150 - Compatibility Chart

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Compatibility Chart 1 Figure 1 to Part 150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES Pt. 150, Fig. 1 Figure 1 to Part 150—Compatibility Chart EC02FE91.079 ...

  17. 46 CFR Figure 1 to Part 150 - Compatibility Chart

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Compatibility Chart 1 Figure 1 to Part 150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES Pt. 150, Fig. 1 Figure 1 to Part 150—Compatibility Chart EC02FE91.079 ...

  18. 46 CFR 150.150 - Exceptions to the compatibility chart.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Exceptions to the compatibility chart. 150.150 Section 150.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.150 Exceptions to the compatibility chart. The Commandant (CG-ENG-5...

  19. 46 CFR Figure 1 to Part 150 - Compatibility Chart

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Compatibility Chart 1 Figure 1 to Part 150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES Pt. 150, Fig. 1 Figure 1 to Part 150—Compatibility Chart EC02FE91.079 ...

  20. 46 CFR 150.150 - Exceptions to the compatibility chart.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Exceptions to the compatibility chart. 150.150 Section 150.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.150 Exceptions to the compatibility chart. The Commandant (CG-ENG-5...

Top