40 CFR 60.5115 - How do I comply with the increment of progress for achieving final compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Model Rule...

40 CFR 60.5100 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Model Rule...

40 CFR 60.1635 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2011 CFR

2011-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 60.1635 Section 60.1635... Combustion Units Constructed on or Before August 30, 1999 Model Rule-Increments of Progress § 60.1635 What must I do if I close my municipal waste combustion unit and then restart my municipal waste combustion...

40 CFR 60.1635 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2013 CFR

2013-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 60.1635 Section 60.1635... Combustion Units Constructed on or Before August 30, 1999 Model Rule-Increments of Progress § 60.1635 What must I do if I close my municipal waste combustion unit and then restart my municipal waste combustion...

40 CFR 60.1635 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2014 CFR

2014-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 60.1635 Section 60.1635... Combustion Units Constructed on or Before August 30, 1999 Model Rule-Increments of Progress § 60.1635 What must I do if I close my municipal waste combustion unit and then restart my municipal waste combustion...

40 CFR 60.1635 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2012 CFR

2012-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 60.1635 Section 60.1635... Combustion Units Constructed on or Before August 30, 1999 Model Rule-Increments of Progress § 60.1635 What must I do if I close my municipal waste combustion unit and then restart my municipal waste combustion...

40 CFR 60.1635 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2010 CFR

2010-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 60.1635 Section 60.1635... Combustion Units Constructed on or Before August 30, 1999 Model Rule-Increments of Progress § 60.1635 What must I do if I close my municipal waste combustion unit and then restart my municipal waste combustion...

40 CFR 60.5085 - What are my requirements for meeting increments of progress and achieving final compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Model Rule...

40 CFR 60.5095 - What must I include in the notifications of achievement of increments of progress?

Code of Federal Regulations, 2011 CFR

2011-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Model Rule...

40 CFR 60.2825 - What must I include in the notifications of achievement of increments of progress?

Code of Federal Regulations, 2014 CFR

2014-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY... Units Model Rule-Air Curtain Incinerators § 60.2825 What must I include in the notifications of...

40 CFR 60.5110 - How do I comply with the increment of progress for submittal of a control plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Model Rule... pollution control and process changes that you will use to comply with the emission limits and standards and...

eFSM--a novel online neural-fuzzy semantic memory model.

PubMed

Tung, Whye Loon; Quek, Chai

2010-01-01

Fuzzy rule-based systems (FRBSs) have been successfully applied to many areas. However, traditional fuzzy systems are often manually crafted, and their rule bases that represent the acquired knowledge are static and cannot be trained to improve the modeling performance. This subsequently leads to intensive research on the autonomous construction and tuning of a fuzzy system directly from the observed training data to address the knowledge acquisition bottleneck, resulting in well-established hybrids such as neural-fuzzy systems (NFSs) and genetic fuzzy systems (GFSs). However, the complex and dynamic nature of real-world problems demands that fuzzy rule-based systems and models be able to adapt their parameters and ultimately evolve their rule bases to address the nonstationary (time-varying) characteristics of their operating environments. Recently, considerable research efforts have been directed to the study of evolving Tagaki-Sugeno (T-S)-type NFSs based on the concept of incremental learning. In contrast, there are very few incremental learning Mamdani-type NFSs reported in the literature. Hence, this paper presents the evolving neural-fuzzy semantic memory (eFSM) model, a neural-fuzzy Mamdani architecture with a data-driven progressively adaptive structure (i.e., rule base) based on incremental learning. Issues related to the incremental learning of the eFSM rule base are carefully investigated, and a novel parameter learning approach is proposed for the tuning of the fuzzy set parameters in eFSM. The proposed eFSM model elicits highly interpretable semantic knowledge in the form of Mamdani-type if-then fuzzy rules from low-level numeric training data. These Mamdani fuzzy rules define the computing structure of eFSM and are incrementally learned with the arrival of each training data sample. New rules are constructed from the emergence of novel training data and obsolete fuzzy rules that no longer describe the recently observed data trends are pruned. This enables eFSM to maintain a current and compact set of Mamdani-type if-then fuzzy rules that collectively generalizes and describes the salient associative mappings between the inputs and outputs of the underlying process being modeled. The learning and modeling performances of the proposed eFSM are evaluated using several benchmark applications and the results are encouraging.

40 CFR 60.1615 - How do I comply with the increment of progress for awarding contracts?

Code of Federal Regulations, 2010 CFR

2010-07-01

... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission..., 1999 Model Rule-Increments of Progress § 60.1615 How do I comply with the increment of progress for...

40 CFR 60.1630 - How do I comply with the increment of progress for achieving final compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Before August 30, 1999 Model Rule-Increments of Progress § 60.1630 How do I comply with the increment of...

40 CFR 60.1610 - How do I comply with the increment of progress for submittal of a control plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Before August 30, 1999 Model Rule-Increments of Progress § 60.1610 How do I comply with the increment of...

40 CFR 60.2590 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Commenced Construction On or Before November 30, 1999 Model Rule-Increments of Progress § 60.2590 When must... increments of progress must be postmarked no later than 10 business days after the compliance date for the...

40 CFR 60.2595 - What if I do not meet an increment of progress?

Code of Federal Regulations, 2010 CFR

2010-07-01

... or Before November 30, 1999 Model Rule-Increments of Progress § 60.2595 What if I do not meet an... Administrator postmarked within 10 business days after the date for that increment of progress in table 1 of...

40 CFR 60.1600 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Before August 30, 1999 Model Rule-Increments of Progress § 60.1600 When must I submit the notifications...

Coordinated control system modelling of ultra-supercritical unit based on a new T-S fuzzy structure.

PubMed

Hou, Guolian; Du, Huan; Yang, Yu; Huang, Congzhi; Zhang, Jianhua

2018-03-01

The thermal power plant, especially the ultra-supercritical unit is featured with severe nonlinearity, strong multivariable coupling. In order to deal with these difficulties, it is of great importance to build an accurate and simple model of the coordinated control system (CCS) in the ultra-supercritical unit. In this paper, an improved T-S fuzzy model identification approach is proposed. First of all, the k-means++ algorithm is employed to identify the premise parameters so as to guarantee the number of fuzzy rules. Then, the local linearized models are determined by using the incremental historical data around the cluster centers, which are obtained via the stochastic gradient descent algorithm with momentum and variable learning rate. Finally, with the proposed method, the CCS model of a 1000 MW USC unit in Tai Zhou power plant is developed. The effectiveness of the proposed approach is validated by the given extensive simulation results, and it can be further employed to design the overall advanced controllers for the CCS in an USC unit. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

Incremental cost effectiveness evaluation in clinical research.

PubMed

Krummenauer, Frank; Landwehr, I

2005-01-28

The health economic evaluation of therapeutic and diagnostic strategies is of increasing importance in clinical research. Therefore also clinical trialists have to involve health economic aspects more frequently. However, whereas they are quite familiar with classical effect measures in clinical trials, the corresponding parameters in health economic evaluation of therapeutic and diagnostic procedures are still not this common. The concepts of incremental cost effectiveness ratios (ICERs) and incremental net health benefit (INHB) will be illustrated and contrasted along the cost effectiveness evaluation of cataract surgery with monofocal and multifocal intraocular lenses. ICERs relate the costs of a treatment to its clinical benefit in terms of a ratio expression (indexed as Euro per clinical benefit unit). Therefore ICERs can be directly compared to a pre-specified willingness to pay (WTP) benchmark, which represents the maximum costs, health insurers would invest to achieve one clinical benefit unit. INHBs estimate a treatment's net clinical benefit after accounting for its cost increase versus an established therapeutic standard. Resource allocation rules can be formulated by means of both effect measures. Both the ICER and the INHB approach enable the definition of directional resource allocation rules. The allocation decisions arising from these rules are identical, as long as the willingness to pay benchmark is fixed in advance. Therefore both strategies crucially call for a priori determination of both the underlying clinical benefit endpoint (such as gain in vision lines after cataract surgery or gain in quality-adjusted life years) and the corresponding willingness to pay benchmark. The use of incremental cost effectiveness and net health benefit estimates provides a rationale for health economic allocation discussions and founding decisions. It implies the same requirements on trial protocols as yet established for clinical trials, that is the a priori definition of primary hypotheses (formulated as an allocation rule involving a pre-specified willingness to pay benchmark) and the primary clinical benefit endpoint (as a rationale for effectiveness evaluation).

40 CFR 60.1620 - How do I comply with the increment of progress for initiating onsite construction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY... or Before August 30, 1999 Model Rule-Increments of Progress § 60.1620 How do I comply with the...

40 CFR 60.1585 - What are my requirements for meeting increments of progress and achieving final compliance?

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY... or Before August 30, 1999 Model Rule-Increments of Progress § 60.1585 What are my requirements for...

40 CFR 60.1625 - How do I comply with the increment of progress for completing onsite construction?

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY... or Before August 30, 1999 Model Rule-Increments of Progress § 60.1625 How do I comply with the...

40 CFR 60.1595 - What must I include in the notifications of achievement of my increments of progress?

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY... or Before August 30, 1999 Model Rule-Increments of Progress § 60.1595 What must I include in the...

40 CFR 60.2830 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Commenced Construction On or Before November 30, 1999 Model Rule-Air Curtain Incinerators § 60.2830 When... increments of progress must be postmarked no later than 10 business days after the compliance date for the...

40 CFR 60.2835 - What if I do not meet an increment of progress?

Code of Federal Regulations, 2010 CFR

2010-07-01

... or Before November 30, 1999 Model Rule-Air Curtain Incinerators § 60.2835 What if I do not meet an... Administrator postmarked within 10 business days after the date for that increment of progress in table 1 of...

Quality and Growth Implications of Incremental Costing Models for Distance Education Units

ERIC Educational Resources Information Center

Crawford, C. B.; Gould, Lawrence V.; King, Dennis; Parker, Carl

2010-01-01

The purpose of this article is to explore quality and growth implications emergent from various incremental costing models applied to distance education units. Prior research relative to costing models and three competing costing models useful in the current distance education environment are discussed. Specifically, the simple costing model, unit…

A new pattern associative memory model for image recognition based on Hebb rules and dot product

NASA Astrophysics Data System (ADS)

Gao, Mingyue; Deng, Limiao; Wang, Yanjiang

2018-04-01

A great number of associative memory models have been proposed to realize information storage and retrieval inspired by human brain in the last few years. However, there is still much room for improvement for those models. In this paper, we extend a binary pattern associative memory model to accomplish real-world image recognition. The learning process is based on the fundamental Hebb rules and the retrieval is implemented by a normalized dot product operation. Our proposed model can not only fulfill rapid memory storage and retrieval for visual information but also have the ability on incremental learning without destroying the previous learned information. Experimental results demonstrate that our model outperforms the existing Self-Organizing Incremental Neural Network (SOINN) and Back Propagation Neuron Network (BPNN) on recognition accuracy and time efficiency.

40 CFR 60.2570 - What are the principal components of the model rule?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What are the principal components of... Construction On or Before November 30, 1999 Use of Model Rule § 60.2570 What are the principal components of... (k) of this section. (a) Increments of progress toward compliance. (b) Waste management plan. (c...

CARIBIAM: constrained Association Rules using Interactive Biological IncrementAl Mining.

PubMed

Rahal, Imad; Rahhal, Riad; Wang, Baoying; Perrizo, William

2008-01-01

This paper analyses annotated genome data by applying a very central data-mining technique known as Association Rule Mining (ARM) with the aim of discovering rules and hypotheses capable of yielding deeper insights into this type of data. In the literature, ARM has been noted for producing an overwhelming number of rules. This work proposes a new technique capable of using domain knowledge in the form of queries in order to efficiently mine only the subset of the associations that are of interest to investigators in an incremental and interactive manner.

A Simple and Accurate Analysis of Conductivity Loss in Millimeter-Wave Helical Slow-Wave Structures

NASA Astrophysics Data System (ADS)

Datta, S. K.; Kumar, Lalit; Basu, B. N.

2009-04-01

Electromagnetic field analysis of a helix slow-wave structure was carried out and a closed form expression was derived for the inductance per unit length of the transmission-line equivalent circuit of the structure, taking into account the actual helix tape dimensions and surface current on the helix over the actual metallic area of the tape. The expression of the inductance per unit length, thus obtained, was used for estimating the increment in the inductance per unit length caused due to penetration of the magnetic flux into the conducting surfaces following Wheeler’s incremental inductance rule, which was subsequently interpreted for the attenuation constant of the propagating structure. The analysis was computationally simple and accurate, and accrues the accuracy of 3D electromagnetic analysis by allowing the use of dispersion characteristics obtainable from any standard electromagnetic modeling. The approach was benchmarked against measurement for two practical structures, and excellent agreement was observed. The analysis was subsequently applied to demonstrate the effects of conductivity on the attenuation constant of a typical broadband millimeter-wave helical slow-wave structure with respect to helix materials and copper plating on the helix, surface finish of the helix, dielectric loading effect and effect of high temperature operation - a comparative study of various such aspects are covered.

77 FR 13632 - Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-07

... Certain Digital Models, Digital Data, and Treatment Plans for Use in Making Incremental Dental Positioning... importation of certain digital models, digital data, and treatment plans for use in making incremental dental... health and welfare in the United States, competitive conditions in the United States economy, the...

Search for Minimal and Semi-Minimal Rule Sets in Incremental Learning of Context-Free and Definite Clause Grammars

NASA Astrophysics Data System (ADS)

Imada, Keita; Nakamura, Katsuhiko

This paper describes recent improvements to Synapse system for incremental learning of general context-free grammars (CFGs) and definite clause grammars (DCGs) from positive and negative sample strings. An important feature of our approach is incremental learning, which is realized by a rule generation mechanism called “bridging” based on bottom-up parsing for positive samples and the search for rule sets. The sizes of rule sets and the computation time depend on the search strategies. In addition to the global search for synthesizing minimal rule sets and serial search, another method for synthesizing semi-optimum rule sets, we incorporate beam search to the system for synthesizing semi-minimal rule sets. The paper shows several experimental results on learning CFGs and DCGs, and we analyze the sizes of rule sets and the computation time.

Drug pricing and control of health expenditures: a comparison between a proportional decision rule and a cost-per-QALY rule.

PubMed

Gandjour, Afschin

2015-01-01

In Germany, the Institute for Quality and Efficiency in Health Care (IQWiG) makes recommendations for reimbursement prices of drugs on the basis of a proportional relationship between costs and health benefits. This paper analyzed the potential of IQWiG's decision rule to control health expenditures and used a cost-per-quality-adjusted life year (QALY) rule as a comparison. A literature search was conducted, and a theoretical model of health expenditure growth was built. The literature search shows that the median incremental cost-effectiveness ratio of German cost-effectiveness analyses was €7650 per QALY gained, thus yielding a much lower threshold cost-effectiveness ratio for IQWiG's rule than an absolute rule at €30 000 per QALY. The theoretical model shows that IQWiG's rule is able to contain the long-term growth of health expenditures under the conservative assumption that future health increases at a constant absolute rate and that the threshold incremental cost-effectiveness ratio increases at a smaller rate than health expenditures. In contrast, an absolute rule offers the potential for manufacturers to raise drug prices in response to the threshold, thus resulting in an initial spike in expenditures. Results suggest that IQWiG's proportional rule will lead to lower drug prices and a slower growth of health expenditures than an absolute cost-effectiveness threshold at €30 000 per QALY. This finding is surprising as IQWiG's rule-in contrast to a cost-per-QALY rule-does not start from a fixed budget. Copyright © 2014 John Wiley & Sons, Ltd.

Optimal tree increment models for the Northeastern United Statesq

Treesearch

Don C. Bragg

2003-01-01

used the potential relative increment (PRI) methodology to develop optimal tree diameter growth models for the Northeastern United States. Thirty species from the Eastwide Forest Inventory Database yielded 69,676 individuals, which were then reduced to fast-growing subsets for PRI analysis. For instance, only 14 individuals from the greater than 6,300-tree eastern...

Optimal Tree Increment Models for the Northeastern United States

Treesearch

Don C. Bragg

2005-01-01

I used the potential relative increment (PRI) methodology to develop optimal tree diameter growth models for the Northeastern United States. Thirty species from the Eastwide Forest Inventory Database yielded 69,676 individuals, which were then reduced to fast-growing subsets for PRI analysis. For instance, only 14 individuals from the greater than 6,300-tree eastern...

Individual tree diameter increment model for managed even-aged stands of ponderosa pine throughout the western United States using a multilevel linear mixed effects model

Treesearch

Fabian C.C. Uzoh; William W. Oliver

2008-01-01

A diameter increment model is developed and evaluated for individual trees of ponderosa pine throughout the species range in the United States using a multilevel linear mixed model. Stochastic variability is broken down among period, locale, plot, tree and within-tree components. Covariates acting at tree and stand level, as breast height diameter, density, site index...

Toward disentangling the effect of hydrologic and nitrogen source changes from 1992 to 2001 on incremental nitrogen yield in the contiguous United States

NASA Astrophysics Data System (ADS)

Alam, Md Jahangir; Goodall, Jonathan L.

2012-04-01

The goal of this research was to quantify the relative impact of hydrologic and nitrogen source changes on incremental nitrogen yield in the contiguous United States. Using nitrogen source estimates from various federal data bases, remotely sensed land use data from the National Land Cover Data program, and observed instream loadings from the United States Geological Survey National Stream Quality Accounting Network program, we calibrated and applied the spatially referenced regression model SPARROW to estimate incremental nitrogen yield for the contiguous United States. We ran different model scenarios to separate the effects of changes in source contributions from hydrologic changes for the years 1992 and 2001, assuming that only state conditions changed and that model coefficients describing the stream water-quality response to changes in state conditions remained constant between 1992 and 2001. Model results show a decrease of 8.2% in the median incremental nitrogen yield over the period of analysis with the vast majority of this decrease due to changes in hydrologic conditions rather than decreases in nitrogen sources. For example, when we changed the 1992 version of the model to have nitrogen source data from 2001, the model results showed only a small increase in median incremental nitrogen yield (0.12%). However, when we changed the 1992 version of the model to have hydrologic conditions from 2001, model results showed a decrease of approximately 8.7% in median incremental nitrogen yield. We did, however, find notable differences in incremental yield estimates for different sources of nitrogen after controlling for hydrologic changes, particularly for population related sources. For example, the median incremental yield for population related sources increased by 8.4% after controlling for hydrologic changes. This is in contrast to a 2.8% decrease in population related sources when hydrologic changes are included in the analysis. Likewise we found that median incremental yield from urban watersheds increased by 6.8% after controlling for hydrologic changes—in contrast to the median incremental nitrogen yield from cropland watersheds, which decreased by 2.1% over the same time period. These results suggest that, after accounting for hydrologic changes, population related sources became a more significant contributor of nitrogen yield to streams in the contiguous United States over the period of analysis. However, this study was not able to account for the influence of human management practices such as improvements in wastewater treatment plants or Best Management Practices that likely improved water quality, due to a lack of data for quantifying the impact of these practices for the study area.

Foundations for Streaming Model Transformations by Complex Event Processing.

PubMed

Dávid, István; Ráth, István; Varró, Dániel

2018-01-01

Streaming model transformations represent a novel class of transformations to manipulate models whose elements are continuously produced or modified in high volume and with rapid rate of change. Executing streaming transformations requires efficient techniques to recognize activated transformation rules over a live model and a potentially infinite stream of events. In this paper, we propose foundations of streaming model transformations by innovatively integrating incremental model query, complex event processing (CEP) and reactive (event-driven) transformation techniques. Complex event processing allows to identify relevant patterns and sequences of events over an event stream. Our approach enables event streams to include model change events which are automatically and continuously populated by incremental model queries. Furthermore, a reactive rule engine carries out transformations on identified complex event patterns. We provide an integrated domain-specific language with precise semantics for capturing complex event patterns and streaming transformations together with an execution engine, all of which is now part of the Viatra reactive transformation framework. We demonstrate the feasibility of our approach with two case studies: one in an advanced model engineering workflow; and one in the context of on-the-fly gesture recognition.

Fuzzy CMAC With incremental Bayesian Ying-Yang learning and dynamic rule construction.

PubMed

Nguyen, M N

2010-04-01

Inspired by the philosophy of ancient Chinese Taoism, Xu's Bayesian ying-yang (BYY) learning technique performs clustering by harmonizing the training data (yang) with the solution (ying). In our previous work, the BYY learning technique was applied to a fuzzy cerebellar model articulation controller (FCMAC) to find the optimal fuzzy sets; however, this is not suitable for time series data analysis. To address this problem, we propose an incremental BYY learning technique in this paper, with the idea of sliding window and rule structure dynamic algorithms. Three contributions are made as a result of this research. First, an online expectation-maximization algorithm incorporated with the sliding window is proposed for the fuzzification phase. Second, the memory requirement is greatly reduced since the entire data set no longer needs to be obtained during the prediction process. Third, the rule structure dynamic algorithm with dynamically initializing, recruiting, and pruning rules relieves the "curse of dimensionality" problem that is inherent in the FCMAC. Because of these features, the experimental results of the benchmark data sets of currency exchange rates and Mackey-Glass show that the proposed model is more suitable for real-time streaming data analysis.

78 FR 22591 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-16

... comments on the proposed rule change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4... applicable to simple orders in the options class under Exchange Rule 6.42--Minimum Increments of Bids and..., with the increment of trading being the standard trading increment applicable to simple orders in the...

Individual tree height increment model for managed even-aged stands of ponderosa pine throughout the western United States using linear mixed effects models

Treesearch

Fabian Uzoh; William W. Oliver

2006-01-01

A height increment model is developed and evaluated for individual trees of ponderosa pine throughout the species range in western United States. The data set used in this study came from long-term permanent research plots in even-aged, pure stands both planted and of natural origin. The data base consists of six levels-of-growing stock studies supplemented by initial...

One Giant Leap for Categorizers: One Small Step for Categorization Theory

PubMed Central

Smith, J. David; Ell, Shawn W.

2015-01-01

We explore humans’ rule-based category learning using analytic approaches that highlight their psychological transitions during learning. These approaches confirm that humans show qualitatively sudden psychological transitions during rule learning. These transitions contribute to the theoretical literature contrasting single vs. multiple category-learning systems, because they seem to reveal a distinctive learning process of explicit rule discovery. A complete psychology of categorization must describe this learning process, too. Yet extensive formal-modeling analyses confirm that a wide range of current (gradient-descent) models cannot reproduce these transitions, including influential rule-based models (e.g., COVIS) and exemplar models (e.g., ALCOVE). It is an important theoretical conclusion that existing models cannot explain humans’ rule-based category learning. The problem these models have is the incremental algorithm by which learning is simulated. Humans descend no gradient in rule-based tasks. Very different formal-modeling systems will be required to explain humans’ psychology in these tasks. An important next step will be to build a new generation of models that can do so. PMID:26332587

The Effect of the Nunn-McCurdy Amendment on Unit-Cost-Growth of Defense Acquisition Projects

DTIC Science & Technology

2010-07-01

Congressional testimony: “I consider Virginia Class cost-reduction efforts a model for all our ships, submarines, and aircraft” (Roughhead, 2009...PATRIOT/MEADS CAP- MISSLE 2004 DE STRYKER 2004 PdE WIN-T INCREMENT 1 2007 PdE WIN-T INCREMENT 2 2007 DE Subtot~l Navy: ADS (ANJWOR-3) 2005 DE AGM...JAVELIN JLENS LONGBOW APACHE LUH PATRIOT PAC-3 PATRIOT/MEADS CAP - FIRE UNIT PATRIOT/MEADS CAP - MISSLE STRYKER WIN-T INCREMENT 1 WIN-T

Anytime synthetic projection: Maximizing the probability of goal satisfaction

NASA Technical Reports Server (NTRS)

Drummond, Mark; Bresina, John L.

1990-01-01

A projection algorithm is presented for incremental control rule synthesis. The algorithm synthesizes an initial set of goal achieving control rules using a combination of situation probability and estimated remaining work as a search heuristic. This set of control rules has a certain probability of satisfying the given goal. The probability is incrementally increased by synthesizing additional control rules to handle 'error' situations the execution system is likely to encounter when following the initial control rules. By using situation probabilities, the algorithm achieves a computationally effective balance between the limited robustness of triangle tables and the absolute robustness of universal plans.

Incremental Refinement of FAÇADE Models with Attribute Grammar from 3d Point Clouds

NASA Astrophysics Data System (ADS)

Dehbi, Y.; Staat, C.; Mandtler, L.; Pl¨umer, L.

2016-06-01

Data acquisition using unmanned aerial vehicles (UAVs) has gotten more and more attention over the last years. Especially in the field of building reconstruction the incremental interpretation of such data is a demanding task. In this context formal grammars play an important role for the top-down identification and reconstruction of building objects. Up to now, the available approaches expect offline data in order to parse an a-priori known grammar. For mapping on demand an on the fly reconstruction based on UAV data is required. An incremental interpretation of the data stream is inevitable. This paper presents an incremental parser of grammar rules for an automatic 3D building reconstruction. The parser enables a model refinement based on new observations with respect to a weighted attribute context-free grammar (WACFG). The falsification or rejection of hypotheses is supported as well. The parser can deal with and adapt available parse trees acquired from previous interpretations or predictions. Parse trees derived so far are updated in an iterative way using transformation rules. A diagnostic step searches for mismatches between current and new nodes. Prior knowledge on façades is incorporated. It is given by probability densities as well as architectural patterns. Since we cannot always assume normal distributions, the derivation of location and shape parameters of building objects is based on a kernel density estimation (KDE). While the level of detail is continuously improved, the geometrical, semantic and topological consistency is ensured.

Expanding the Role of Psychiatric Mental Health Nurse Practitioners in a State Psychiatric System: The New Hampshire Experience.

PubMed

de Nesnera, Alexander; Allen, Diane E

2016-05-01

Psychiatric mental health nurse practitioners (PMHNPs) are assuming increasing clinical responsibilities in the treatment of individuals with mental illness as the shortage of psychiatrists and their maldistribution continues to persist in the United States. States vary widely in their statutes and administrative rules delineating PMHNP's scope of practice. This column describes the legislative process of incremental changes in New Hampshire statute and rules changes over the past 15 years that have significantly expanded PMHNP's ability to treat individuals with mental illnesses in the state mental health system. PMHNPs have worked closely with physician leaders and policy makers to allow this to occur.

Incremental Learning of Context Free Grammars by Parsing-Based Rule Generation and Rule Set Search

NASA Astrophysics Data System (ADS)

Nakamura, Katsuhiko; Hoshina, Akemi

This paper discusses recent improvements and extensions in Synapse system for inductive inference of context free grammars (CFGs) from sample strings. Synapse uses incremental learning, rule generation based on bottom-up parsing, and the search for rule sets. The form of production rules in the previous system is extended from Revised Chomsky Normal Form A→βγ to Extended Chomsky Normal Form, which also includes A→B, where each of β and γ is either a terminal or nonterminal symbol. From the result of bottom-up parsing, a rule generation mechanism synthesizes minimum production rules required for parsing positive samples. Instead of inductive CYK algorithm in the previous version of Synapse, the improved version uses a novel rule generation method, called ``bridging,'' which bridges the lacked part of the derivation tree for the positive string. The improved version also employs a novel search strategy, called serial search in addition to minimum rule set search. The synthesis of grammars by the serial search is faster than the minimum set search in most cases. On the other hand, the size of the generated CFGs is generally larger than that by the minimum set search, and the system can find no appropriate grammar for some CFL by the serial search. The paper shows experimental results of incremental learning of several fundamental CFGs and compares the methods of rule generation and search strategies.

40 CFR Table 1 to Subpart Bbbb of... - Model Rule-Compliance Schedules and Increments of Progress

Code of Federal Regulations, 2010 CFR

2010-07-01

... modification after June 26, 1987, comply with the dioxins/furans and mercury limits by the later of two dates... the dioxins/furans limits must be achieved no later than December 6, 2005, even if the date one year...

75 FR 1433 - Self-Regulatory Organizations; NASDAQ OMX PHLX, Inc.; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-11

... all options series of SPY and IWM as eligible to quote in $0.01 increments, regardless of premium... Rule Change To Allow All SPY and IWM Option Series To Quote in Penny Increments January 4, 2010. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934 (``Act'') \\1\\ and Rule 19b-4 \\2...

Development and validation of a risk model for identification of non-neutropenic, critically ill adult patients at high risk of invasive Candida infection: the Fungal Infection Risk Evaluation (FIRE) Study.

PubMed

Harrison, D; Muskett, H; Harvey, S; Grieve, R; Shahin, J; Patel, K; Sadique, Z; Allen, E; Dybowski, R; Jit, M; Edgeworth, J; Kibbler, C; Barnes, R; Soni, N; Rowan, K

2013-02-01

There is increasing evidence that invasive fungal disease (IFD) is more likely to occur in non-neutropenic patients in critical care units. A number of randomised controlled trials (RCTs) have evaluated antifungal prophylaxis in non-neutropenic, critically ill patients, demonstrating a reduction in the risk of proven IFD and suggesting a reduction in mortality. It is necessary to establish a method to identify and target antifungal prophylaxis at those patients at highest risk of IFD, who stand to benefit most from any antifungal prophylaxis strategy. To develop and validate risk models to identify non-neutropenic, critically ill adult patients at high risk of invasive Candida infection, who would benefit from antifungal prophylaxis, and to assess the cost-effectiveness of targeting antifungal prophylaxis to high-risk patients based on these models. Systematic review, prospective data collection, statistical modelling, economic decision modelling and value of information analysis. Ninety-six UK adult general critical care units. Consecutive admissions to participating critical care units. None. Invasive fungal disease, defined as a blood culture or sample from a normally sterile site showing yeast/mould cells in a microbiological or histopathological report. For statistical and economic modelling, the primary outcome was invasive Candida infection, defined as IFD-positive for Candida species. Systematic review: Thirteen articles exploring risk factors, risk models or clinical decision rules for IFD in critically ill adult patients were identified. Risk factors reported to be significantly associated with IFD were included in the final data set for the prospective data collection. Data were collected on 60,778 admissions between July 2009 and March 2011. Overall, 383 patients (0.6%) were admitted with or developed IFD. The majority of IFD patients (94%) were positive for Candida species. The most common site of infection was blood (55%). The incidence of IFD identified in unit was 4.7 cases per 1000 admissions, and for unit-acquired IFD was 3.2 cases per 1000 admissions. Statistical modelling: Risk models were developed at admission to the critical care unit, 24 hours and the end of calendar day 3. The risk model at admission had fair discrimination (c-index 0.705). Discrimination improved at 24 hours (c-index 0.823) and this was maintained at the end of calendar day 3 (c-index 0.835). There was a drop in model performance in the validation sample. Economic decision model: Irrespective of risk threshold, incremental quality-adjusted life-years of prophylaxis strategies compared with current practice were positive but small compared with the incremental costs. Incremental net benefits of each prophylaxis strategy compared with current practice were all negative. Cost-effectiveness acceptability curves showed that current practice was the strategy most likely to be cost-effective. Across all parameters in the decision model, results indicated that the value of further research for the whole population of interest might be high relative to the research costs. The results of the Fungal Infection Risk Evaluation (FIRE) Study, derived from a highly representative sample of adult general critical care units across the UK, indicated a low incidence of IFD among non-neutropenic, critically ill adult patients. IFD was associated with substantially higher mortality, more intensive organ support and longer length of stay. Risk modelling produced simple risk models that provided acceptable discrimination for identifying patients at 'high risk' of invasive Candida infection. Results of the economic model suggested that the current most cost-effective treatment strategy for prophylactic use of systemic antifungal agents among non-neutropenic, critically ill adult patients admitted to NHS adult general critical care units is a strategy of no risk assessment and no antifungal prophylaxis. Funding for this study was provided by the Health Technology Assessment programme of the National Institute for Health Research.

75 FR 1434 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-11

... minimum quoting increment for bids and offers in SPY and IWM is $0.01 for all options series below $3.00... Proposed Rule Change To Allow All SPY and IWM Option Series To Quote in Penny Increments January 4, 2010. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934 (``Act'') \\1\\ and Rule 19b-4 \\2...

A novel approach for incremental uncertainty rule generation from databases with missing values handling: application to dynamic medical databases.

PubMed

Konias, Sokratis; Chouvarda, Ioanna; Vlahavas, Ioannis; Maglaveras, Nicos

2005-09-01

Current approaches for mining association rules usually assume that the mining is performed in a static database, where the problem of missing attribute values does not practically exist. However, these assumptions are not preserved in some medical databases, like in a home care system. In this paper, a novel uncertainty rule algorithm is illustrated, namely URG-2 (Uncertainty Rule Generator), which addresses the problem of mining dynamic databases containing missing values. This algorithm requires only one pass from the initial dataset in order to generate the item set, while new metrics corresponding to the notion of Support and Confidence are used. URG-2 was evaluated over two medical databases, introducing randomly multiple missing values for each record's attribute (rate: 5-20% by 5% increments) in the initial dataset. Compared with the classical approach (records with missing values are ignored), the proposed algorithm was more robust in mining rules from datasets containing missing values. In all cases, the difference in preserving the initial rules ranged between 30% and 60% in favour of URG-2. Moreover, due to its incremental nature, URG-2 saved over 90% of the time required for thorough re-mining. Thus, the proposed algorithm can offer a preferable solution for mining in dynamic relational databases.

Abstraction and Assume-Guarantee Reasoning for Automated Software Verification

NASA Technical Reports Server (NTRS)

Chaki, S.; Clarke, E.; Giannakopoulou, D.; Pasareanu, C. S.

2004-01-01

Compositional verification and abstraction are the key techniques to address the state explosion problem associated with model checking of concurrent software. A promising compositional approach is to prove properties of a system by checking properties of its components in an assume-guarantee style. This article proposes a framework for performing abstraction and assume-guarantee reasoning of concurrent C code in an incremental and fully automated fashion. The framework uses predicate abstraction to extract and refine finite state models of software and it uses an automata learning algorithm to incrementally construct assumptions for the compositional verification of the abstract models. The framework can be instantiated with different assume-guarantee rules. We have implemented our approach in the COMFORT reasoning framework and we show how COMFORT out-performs several previous software model checking approaches when checking safety properties of non-trivial concurrent programs.

Automating Rule Strengths in Expert Systems.

DTIC Science & Technology

1987-05-01

systems were designed in an incremental, iterative way. One of the most easily identifiable phases in this process, sometimes called tuning, consists...attenuators. The designer of the knowledge-based system must determine (synthesize) or adjust (xfine, if estimates of the values are given) these...values. We consider two ways in which the designer can learn the values. We call the first model of learning the complete case and the second model the

Two models of minimalist, incremental syntactic analysis.

PubMed

Stabler, Edward P

2013-07-01

Minimalist grammars (MGs) and multiple context-free grammars (MCFGs) are weakly equivalent in the sense that they define the same languages, a large mildly context-sensitive class that properly includes context-free languages. But in addition, for each MG, there is an MCFG which is strongly equivalent in the sense that it defines the same language with isomorphic derivations. However, the structure-building rules of MGs but not MCFGs are defined in a way that generalizes across categories. Consequently, MGs can be exponentially more succinct than their MCFG equivalents, and this difference shows in parsing models too. An incremental, top-down beam parser for MGs is defined here, sound and complete for all MGs, and hence also capable of parsing all MCFG languages. But since the parser represents its grammar transparently, the relative succinctness of MGs is again evident. Although the determinants of MG structure are narrowly and discretely defined, probabilistic influences from a much broader domain can influence even the earliest analytic steps, allowing frequency and context effects to come early and from almost anywhere, as expected in incremental models. Copyright © 2013 Cognitive Science Society, Inc.

Analytic description of the frictionally engaged in-plane bending process incremental swivel bending (ISB)

NASA Astrophysics Data System (ADS)

Frohn, Peter; Engel, Bernd; Groth, Sebastian

2018-05-01

Kinematic forming processes shape geometries by the process parameters to achieve a more universal process utilizations regarding geometric configurations. The kinematic forming process Incremental Swivel Bending (ISB) bends sheet metal strips or profiles in plane. The sequence for bending an arc increment is composed of the steps clamping, bending, force release and feed. The bending moment is frictionally engaged by two clamping units in a laterally adjustable bending pivot. A minimum clamping force hindering the material from slipping through the clamping units is a crucial criterion to achieve a well-defined incremental arc. Therefore, an analytic description of a singular bent increment is developed in this paper. The bending moment is calculated by the uniaxial stress distribution over the profiles' width depending on the bending pivot's position. By a Coulomb' based friction model, necessary clamping force is described in dependence of friction, offset, dimensions of the clamping tools and strip thickness as well as material parameters. Boundaries for the uniaxial stress calculation are given in dependence of friction, tools' dimensions and strip thickness. The results indicate that changing the bending pivot to an eccentric position significantly affects the process' bending moment and, hence, clamping force, which is given in dependence of yield stress and hardening exponent. FE simulations validate the model with satisfactory accordance.

78 FR 20179 - Changes to Representation of Others Before The United States Patent and Trademark Office

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-03

...The United States Patent and Trademark Office (Office or USPTO) is adopting the new USPTO Rules of Professional Conduct (USPTO Rules), which are based on the American Bar Association's (ABA) Model Rules of Professional Conduct (ABA Model Rules), which were published in 1983, substantially revised in 2003 and updated through 2012. The Office has also revised the existing procedural rules governing disciplinary investigations and proceedings. These changes will enable the Office to better protect the public while also providing practitioners with substantially uniform disciplinary rules across multiple jurisdictions.

Using Predictability for Lexical Segmentation.

PubMed

Çöltekin, Çağrı

2017-09-01

This study investigates a strategy based on predictability of consecutive sub-lexical units in learning to segment a continuous speech stream into lexical units using computational modeling and simulations. Lexical segmentation is one of the early challenges during language acquisition, and it has been studied extensively through psycholinguistic experiments as well as computational methods. However, despite strong empirical evidence, the explicit use of predictability of basic sub-lexical units in models of segmentation is underexplored. This paper presents an incremental computational model of lexical segmentation for exploring the usefulness of predictability for lexical segmentation. We show that the predictability cue is a strong cue for segmentation. Contrary to earlier reports in the literature, the strategy yields state-of-the-art segmentation performance with an incremental computational model that uses only this particular cue in a cognitively plausible setting. The paper also reports an in-depth analysis of the model, investigating the conditions affecting the usefulness of the strategy. Copyright © 2016 Cognitive Science Society, Inc.

HyFIS: adaptive neuro-fuzzy inference systems and their application to nonlinear dynamical systems.

PubMed

Kim, J; Kasabov, N

1999-11-01

This paper proposes an adaptive neuro-fuzzy system, HyFIS (Hybrid neural Fuzzy Inference System), for building and optimising fuzzy models. The proposed model introduces the learning power of neural networks to fuzzy logic systems and provides linguistic meaning to the connectionist architectures. Heuristic fuzzy logic rules and input-output fuzzy membership functions can be optimally tuned from training examples by a hybrid learning scheme comprised of two phases: rule generation phase from data; and rule tuning phase using error backpropagation learning scheme for a neural fuzzy system. To illustrate the performance and applicability of the proposed neuro-fuzzy hybrid model, extensive simulation studies of nonlinear complex dynamic systems are carried out. The proposed method can be applied to an on-line incremental adaptive learning for the prediction and control of nonlinear dynamical systems. Two benchmark case studies are used to demonstrate that the proposed HyFIS system is a superior neuro-fuzzy modelling technique.

75 FR 5365 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... SPY and IWM as eligible to quote in $0.01 increments, regardless of premium value. The Exchange will... operative delay will allow the Exchange to commence quoting all series of IWM and SPY in increments of $0.01... Proposed Rule Change To Allow All SPY and IWM Options Series To Quote in Penny Increments January 27, 2010...

Increment and mortality in a virgin Douglas-fir forest.

Treesearch

Robert W. Steele; Norman P. Worthington

1955-01-01

Is there any basis to the forester's rule of thumb that virgin forests eventually reach an equilibrium where increment and mortality approximately balance? Are we wasting potential timber volume by failing to salvage mortality in old-growth stands?

New fundamental parameters for attitude representation

NASA Astrophysics Data System (ADS)

Patera, Russell P.

2017-08-01

A new attitude parameter set is developed to clarify the geometry of combining finite rotations in a rotational sequence and in combining infinitesimal angular increments generated by angular rate. The resulting parameter set of six Pivot Parameters represents a rotation as a great circle arc on a unit sphere that can be located at any clocking location in the rotation plane. Two rotations are combined by linking their arcs at either of the two intersection points of the respective rotation planes. In a similar fashion, linking rotational increments produced by angular rate is used to derive the associated kinematical equations, which are linear and have no singularities. Included in this paper is the derivation of twelve Pivot Parameter elements that represent all twelve Euler Angle sequences, which enables efficient conversions between Pivot Parameters and any Euler Angle sequence. Applications of this new parameter set include the derivation of quaternions and the quaternion composition rule, as well as, the derivation of the analytical solution to time dependent coning motion. The relationships between Pivot Parameters and traditional parameter sets are included in this work. Pivot Parameters are well suited for a variety of aerospace applications due to their effective composition rule, singularity free kinematic equations, efficient conversion to and from Euler Angle sequences and clarity of their geometrical foundation.

77 FR 75234 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

... Proposed Rule Change To Extend the Penny Pilot Program December 13, 2012. Pursuant to Section 19(b)(1) of... Proposed Rule Change BOX Options Exchange LLC (the ``Exchange'') proposes to amend Rule 7260 (Penny Pilot... penny increments (``Penny Pilot Program''). The text of the proposed rule change is available from the...

78 FR 29157 - Certain Digital Models, Digital Data, and Treatment Plans for Use, in Making Incremental Dental...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-17

... INTERNATIONAL TRADE COMMISSION Certain Digital Models, Digital Data, and Treatment Plans for Use... conditions in the United States economy, the production of like or directly competitive articles in the..., competitive conditions in the United States economy, the production of like or directly competitive articles...

The high-temperature heat capacity of the (Th,U)O 2 and (U,Pu)O 2 solid solutions

DOE PAGES

Valu, S. O.; Benes, O.; Manara, D.; ...

2016-11-09

The enthalpy increment data for the (Th,U)O 2 and (U,Pu)O 2 solid solutions are reviewed and complemented with new experimental data (400–1773 K) and many-body potential model simulations. The results of the review show that from room temperature up to about 2000 K the enthalpy data are in agreement with the additivity rule (Neumann-Kopp) in the whole composition range. Above 2000 K the effect of Oxygen Frenkel Pair (OFP) formation leads to an excess enthalpy (heat capacity) that is modeled using the enthalpy and entropy of OFP formation from the end-members. Here, a good agreement with existing experimental work ismore » observed, and a reasonable agreement with the results of the many-body potential model, which indicate the presence of the diffuse Bredig (superionic) transition that is not found in the experimental enthalpy increment data.« less

Scalability of a Methodology for Generating Technical Trading Rules with GAPs Based on Risk-Return Adjustment and Incremental Training

NASA Astrophysics Data System (ADS)

de La Cal, E. A.; Fernández, E. M.; Quiroga, R.; Villar, J. R.; Sedano, J.

In previous works a methodology was defined, based on the design of a genetic algorithm GAP and an incremental training technique adapted to the learning of series of stock market values. The GAP technique consists in a fusion of GP and GA. The GAP algorithm implements the automatic search for crisp trading rules taking as objectives of the training both the optimization of the return obtained and the minimization of the assumed risk. Applying the proposed methodology, rules have been obtained for a period of eight years of the S&P500 index. The achieved adjustment of the relation return-risk has generated rules with returns very superior in the testing period to those obtained applying habitual methodologies and even clearly superior to Buy&Hold. This work probes that the proposed methodology is valid for different assets in a different market than previous work.

40 CFR 60.2570 - What are the principal components of the model rule?

Code of Federal Regulations, 2012 CFR

2012-07-01

... the model rule? 60.2570 Section 60.2570 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Use of Model Rule...

40 CFR 60.2570 - What are the principal components of the model rule?

Code of Federal Regulations, 2013 CFR

2013-07-01

... the model rule? 60.2570 Section 60.2570 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Use of Model Rule...

40 CFR 60.2570 - What are the principal components of the model rule?

Code of Federal Regulations, 2014 CFR

2014-07-01

... the model rule? 60.2570 Section 60.2570 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Use of Model Rule...

76 FR 76212 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-06

... this Rule. Also, the provisions of Rule 1033(b) and (c), Rule 1034 and Rule 1038 do not apply to orders... trading procedures were limited to options classes traded in $0.05 or $0.10 standard increments. The $1... is consistent with the provisions of Section 6 of the Act,\\10\\ in general, and with Section 6(b)(5...

77 FR 68871 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

... this Rule. Also, the provisions of Rule 1033(b) and (c), Rule 1034 and Rule 1038 do not apply to orders... effective proposal that extended the pilot program until December 1, 2012.\\10\\ The Exchange now proposes an... trading procedures were limited to options classes traded in $0.05 or $0.10 standard increments. The $1...

77 FR 68876 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

... this Rule. Also, the provisions of Rule 1033(b) and (c), Rule 1034 and Rule 1038 do not apply to orders... effective proposal that extended the pilot program until December 1, 2012.\\10\\ The Exchange now proposes an... trading procedures were limited to options classes traded in $0.05 or $0.10 standard increments. The $1...

FERC examines transmission access pricing policies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burkhart, L.A.

1993-02-15

The Federal Energy Regulatory Commission (FERC) has approved two orders dealing with transmission pricing issues that evolved from its March 1992 Pennsylvania Electric Co. (Penelec) decision dealing with cost recovery of transmission plant expansion. Commissioner Betsy Moler said the cases represented the first time the FERC has used incremental rates for wheeling transactions. In the first new order, Public Service Electric Gas Co. proposed charging for third-party transmission services to recover the sum of its standard embedded cost rate and the net incremental cost of making upgrades to its integrated transmission system. Public Service sought to provide service to EEAmore » I Limited, which proposed building and operating a cogeneration facility at a United States Gypsum Co. plant in New Jersey. Consolidated Edison Company of New York Inc. had agreed to purchase the project's output. In rejecting Public Service's proposal, the FERC ruled the utility must charge a transmission rate that is the higher of either its embedded cost rate or its incremental cost rate of accelerated expansion. (In this instance, the incremental rate was higher). In the second new order, Public Service Co. of Colorado (PSCC) filed a proposed open access transmission service tariff related to its acquisition of facilities from Colorado-Ute Electric Association Inc. The FERC rejected PSCC's tariff request that would have required a new transmission customer (in the event PSCC modified its integrated transmission grid) to pay the sum of PSCC's standard transmission rate (reflecting the average cost of the grid facilities) plus the expansion cost (reflecting the incremental facility cost).« less

40 CFR 60.5080 - What are the principal components of the model rule?

Code of Federal Regulations, 2011 CFR

2011-07-01

... the model rule? 60.5080 Section 60.5080 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Use of Model Rule § 60.5080 What...

78 FR 971 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-07

... Effectiveness of a Proposed Rule Change Relating to the Exchange Penny Pilot Program December 31, 2012. Pursuant... its rules relating to the Penny Pilot Program. The text of the proposed rule change is provided below... decimal increments for bids and offers for all series of the option classes participating in the Penny...

40 CFR 52.1773 - Conditional approval.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Deterioration (PSD) infrastructure requirements for the 1997 annual and 2006 24-hour fine particulate matter... to the PM2.5 standard for their PSD program and committing to providing the necessary SIP revision to... PM2.5 Rule (including PM2.5 PSD Increment-SILs-SMC, as it relates to PM2.5 increments to meet the...

40 CFR 52.1773 - Conditional approval.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Deterioration (PSD) infrastructure requirements for the 1997 annual and 2006 24-hour fine particulate matter... to the PM2.5 standard for their PSD program and committing to providing the necessary SIP revision to... PM2.5 Rule (including PM2.5 PSD Increment-SILs-SMC, as it relates to PM2.5 increments to meet the...

Bridging the gap between health and non-health investments: moving from cost-effectiveness analysis to a return on investment approach across sectors of economy.

PubMed

Sendi, Pedram

2008-06-01

When choosing from a menu of treatment alternatives, the optimal treatment depends on the objective function and the assumptions of the model. The classical decision rule of cost-effectiveness analysis may be formulated via two different objective functions: (i) maximising health outcomes subject to the budget constraint or (ii) maximising the net benefit of the intervention with the budget being determined ex post. We suggest a more general objective function of (iii) maximising return on investment from available resources with consideration of health and non-health investments. The return on investment approach allows to adjust the analysis for the benefits forgone by alternative non-health investments from a societal or subsocietal perspective. We show that in the presence of positive returns on non-health investments the decision-maker's willingness to pay per unit of effect for a treatment program needs to be higher than its incremental cost-effectiveness ratio to be considered cost-effective.

First- and Second-Line Bevacizumab in Addition to Chemotherapy for Metastatic Colorectal Cancer: A United States–Based Cost-Effectiveness Analysis

PubMed Central

Goldstein, Daniel A.; Chen, Qiushi; Ayer, Turgay; Howard, David H.; Lipscomb, Joseph; El-Rayes, Bassel F.; Flowers, Christopher R.

2015-01-01

Purpose The addition of bevacizumab to fluorouracil-based chemotherapy is a standard of care for previously untreated metastatic colorectal cancer. Continuation of bevacizumab beyond progression is an accepted standard of care based on a 1.4-month increase in median overall survival observed in a randomized trial. No United States–based cost-effectiveness modeling analyses are currently available addressing the use of bevacizumab in metastatic colorectal cancer. Our objective was to determine the cost effectiveness of bevacizumab in the first-line setting and when continued beyond progression from the perspective of US payers. Methods We developed two Markov models to compare the cost and effectiveness of fluorouracil, leucovorin, and oxaliplatin with or without bevacizumab in the first-line treatment and subsequent fluorouracil, leucovorin, and irinotecan with or without bevacizumab in the second-line treatment of metastatic colorectal cancer. Model robustness was addressed by univariable and probabilistic sensitivity analyses. Health outcomes were measured in life-years and quality-adjusted life-years (QALYs). Results Using bevacizumab in first-line therapy provided an additional 0.10 QALYs (0.14 life-years) at a cost of $59,361. The incremental cost-effectiveness ratio was $571,240 per QALY. Continuing bevacizumab beyond progression provided an additional 0.11 QALYs (0.16 life-years) at a cost of $39,209. The incremental cost-effectiveness ratio was $364,083 per QALY. In univariable sensitivity analyses, the variables with the greatest influence on the incremental cost-effectiveness ratio were bevacizumab cost, overall survival, and utility. Conclusion Bevacizumab provides minimal incremental benefit at high incremental cost per QALY in both the first- and second-line settings of metastatic colorectal cancer treatment. PMID:25691669

Rolling scheduling of electric power system with wind power based on improved NNIA algorithm

NASA Astrophysics Data System (ADS)

Xu, Q. S.; Luo, C. J.; Yang, D. J.; Fan, Y. H.; Sang, Z. X.; Lei, H.

2017-11-01

This paper puts forth a rolling modification strategy for day-ahead scheduling of electric power system with wind power, which takes the operation cost increment of unit and curtailed wind power of power grid as double modification functions. Additionally, an improved Nondominated Neighbor Immune Algorithm (NNIA) is proposed for solution. The proposed rolling scheduling model has further improved the operation cost of system in the intra-day generation process, enhanced the system’s accommodation capacity of wind power, and modified the key transmission section power flow in a rolling manner to satisfy the security constraint of power grid. The improved NNIA algorithm has defined an antibody preference relation model based on equal incremental rate, regulation deviation constraints and maximum & minimum technical outputs of units. The model can noticeably guide the direction of antibody evolution, and significantly speed up the process of algorithm convergence to final solution, and enhance the local search capability.

77 FR 40123 - Self-Regulatory Organizations; BOX Options Exchange, LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... Rule Change To Extend the Penny Pilot Program June 29, 2012. Pursuant to Section 19(b)(1) \\1\\ of the... Proposed Rule Change The Exchange proposes to amend Rule 7260 (Penny Pilot Program) to extend, through December 31, 2012, the pilot program that permits certain classes to be quoted in penny increments (``Penny...

Incremental value of copeptin to highly sensitive cardiac Troponin I for rapid rule-out of myocardial infarction.

PubMed

Wildi, Karin; Zellweger, Christa; Twerenbold, Raphael; Jaeger, Cedric; Reichlin, Tobias; Haaf, Philip; Faoro, Jonathan; Giménez, Maria Rubini; Fischer, Andreas; Nelles, Berit; Druey, Sophie; Krivoshei, Lian; Hillinger, Petra; Puelacher, Christian; Herrmann, Thomas; Campodarve, Isabel; Rentsch, Katharina; Steuer, Stephan; Osswald, Stefan; Mueller, Christian

2015-01-01

The incremental value of copeptin, a novel marker of endogenous stress, for rapid rule-out of non-ST-elevation myocardial infarction (NSTEMI) is unclear when sensitive or even high-sensitivity cardiac troponin cTn (hs-cTn) assays are used. In an international multicenter study we evaluated 1929 consecutive patients with symptoms suggestive of acute myocardial infarction (AMI). Measurements of copeptin, three sensitive and three hs-cTn assays were performed at presentation in a blinded fashion. The final diagnosis was adjudicated by two independent cardiologists using all clinical information including coronary angiography and levels of hs-cTnT. The incremental value in the diagnosis of NSTEMI was quantified using four outcome measures: area under the receiver-operating characteristic curve (AUC), integrated discrimination improvement (IDI), sensitivity and negative predictive value (NPV). Early presenters (< 4h since chest pain onset) were a pre-defined subgroup. NSTEMI was the adjudicated final diagnosis in 358 (18.6%) patients. As compared to the use of cTn alone, copeptin significantly increased AUC for two (33%) and IDI (between 0.010 and 0.041 (all p < 0.01)), sensitivity and NPV for all six cTn assays (100%); NPV to 96-99% when the 99 th percentile of the respective cTnI assay was combined with a copeptin level of 9 pmol/l (all p < 0.01). The incremental value in early presenters was similar to that of the overall cohort. When used for rapid rule-out of NSTEM in combination with sensitive or hs-cTnI assays, copeptin provides a numerically small, but statistically and likely also clinically significant incremental value. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

40 CFR 60.5075 - How does the model rule relate to the required elements of my state plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Use of Model Rule...

A network model of behavioural performance in a rule learning task.

PubMed

Hasselmo, Michael E; Stern, Chantal E

2018-04-19

Humans demonstrate differences in performance on cognitive rule learning tasks which could involve differences in properties of neural circuits. An example model is presented to show how gating of the spread of neural activity could underlie rule learning and the generalization of rules to previously unseen stimuli. This model uses the activity of gating units to regulate the pattern of connectivity between neurons responding to sensory input and subsequent gating units or output units. This model allows analysis of network parameters that could contribute to differences in cognitive rule learning. These network parameters include differences in the parameters of synaptic modification and presynaptic inhibition of synaptic transmission that could be regulated by neuromodulatory influences on neural circuits. Neuromodulatory receptors play an important role in cognitive function, as demonstrated by the fact that drugs that block cholinergic muscarinic receptors can cause cognitive impairments. In discussions of the links between neuromodulatory systems and biologically based traits, the issue of mechanisms through which these linkages are realized is often missing. This model demonstrates potential roles of neural circuit parameters regulated by acetylcholine in learning context-dependent rules, and demonstrates the potential contribution of variation in neural circuit properties and neuromodulatory function to individual differences in cognitive function.This article is part of the theme issue 'Diverse perspectives on diversity: multi-disciplinary approaches to taxonomies of individual differences'. © 2018 The Author(s).

Bigger is Better, but at What Cost? Estimating the Economic Value of Incremental Data Assets.

PubMed

Dalessandro, Brian; Perlich, Claudia; Raeder, Troy

2014-06-01

Many firms depend on third-party vendors to supply data for commercial predictive modeling applications. An issue that has received very little attention in the prior research literature is the estimation of a fair price for purchased data. In this work we present a methodology for estimating the economic value of adding incremental data to predictive modeling applications and present two cases studies. The methodology starts with estimating the effect that incremental data has on model performance in terms of common classification evaluation metrics. This effect is then translated into economic units, which gives an expected economic value that the firm might realize with the acquisition of a particular data asset. With this estimate a firm can then set a data acquisition price that targets a particular return on investment. This article presents the methodology in full detail and illustrates it in the context of two marketing case studies.

40 CFR Table 2 to Subpart Mmmm of... - Model Rule-Emission Limits and Standards for Existing Fluidized Bed Sewage Sludge Incineration Units

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Model Rule-Emission Limits and Standards for Existing Fluidized Bed Sewage Sludge Incineration Units 2 Table 2 to Subpart MMMM of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF...

40 CFR Table 2 to Subpart Mmmm of... - Model Rule-Emission Limits and Standards for Existing Fluidized Bed Sewage Sludge Incineration Units

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Model Rule-Emission Limits and Standards for Existing Fluidized Bed Sewage Sludge Incineration Units 2 Table 2 to Subpart MMMM of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF...

Feature-constrained surface reconstruction approach for point cloud data acquired with 3D laser scanner

NASA Astrophysics Data System (ADS)

Wang, Yongbo; Sheng, Yehua; Lu, Guonian; Tian, Peng; Zhang, Kai

2008-04-01

Surface reconstruction is an important task in the field of 3d-GIS, computer aided design and computer graphics (CAD & CG), virtual simulation and so on. Based on available incremental surface reconstruction methods, a feature-constrained surface reconstruction approach for point cloud is presented. Firstly features are extracted from point cloud under the rules of curvature extremes and minimum spanning tree. By projecting local sample points to the fitted tangent planes and using extracted features to guide and constrain the process of local triangulation and surface propagation, topological relationship among sample points can be achieved. For the constructed models, a process named consistent normal adjustment and regularization is adopted to adjust normal of each face so that the correct surface model is achieved. Experiments show that the presented approach inherits the convenient implementation and high efficiency of traditional incremental surface reconstruction method, meanwhile, it avoids improper propagation of normal across sharp edges, which means the applicability of incremental surface reconstruction is greatly improved. Above all, appropriate k-neighborhood can help to recognize un-sufficient sampled areas and boundary parts, the presented approach can be used to reconstruct both open and close surfaces without additional interference.

Pornographic image recognition and filtering using incremental learning in compressed domain

NASA Astrophysics Data System (ADS)

Zhang, Jing; Wang, Chao; Zhuo, Li; Geng, Wenhao

2015-11-01

With the rapid development and popularity of the network, the openness, anonymity, and interactivity of networks have led to the spread and proliferation of pornographic images on the Internet, which have done great harm to adolescents' physical and mental health. With the establishment of image compression standards, pornographic images are mainly stored with compressed formats. Therefore, how to efficiently filter pornographic images is one of the challenging issues for information security. A pornographic image recognition and filtering method in the compressed domain is proposed by using incremental learning, which includes the following steps: (1) low-resolution (LR) images are first reconstructed from the compressed stream of pornographic images, (2) visual words are created from the LR image to represent the pornographic image, and (3) incremental learning is adopted to continuously adjust the classification rules to recognize the new pornographic image samples after the covering algorithm is utilized to train and recognize the visual words in order to build the initial classification model of pornographic images. The experimental results show that the proposed pornographic image recognition method using incremental learning has a higher recognition rate as well as costing less recognition time in the compressed domain.

Cost-Effectiveness Analysis of a Transparent Antimicrobial Dressing for Managing Central Venous and Arterial Catheters in Intensive Care Units

PubMed Central

Bernatchez, Stéphanie F.; Ruckly, Stéphane; Timsit, Jean-François

2015-01-01

Objective To model the cost-effectiveness impact of routine use of an antimicrobial chlorhexidine gluconate-containing securement dressing compared to non-antimicrobial transparent dressings for the protection of central vascular lines in intensive care unit patients. Design This study uses a novel health economic model to estimate the cost-effectiveness of using the chlorhexidine gluconate dressing versus transparent dressings in a French intensive care unit scenario. The 30-day time non-homogeneous markovian model comprises eight health states. The probabilities of events derive from a multicentre (12 French intensive care units) randomized controlled trial. 1,000 Monte Carlo simulations of 1,000 patients per dressing strategy are used for probabilistic sensitivity analysis and 95% confidence intervals calculations. The outcome is the number of catheter-related bloodstream infections avoided. Costs of intensive care unit stay are based on a recent French multicentre study and the cost-effectiveness criterion is the cost per catheter-related bloodstream infections avoided. The incremental net monetary benefit per patient is also estimated. Patients 1000 patients per group simulated based on the source randomized controlled trial involving 1,879 adults expected to require intravascular catheterization for 48 hours. Intervention Chlorhexidine Gluconate-containing securement dressing compared to non-antimicrobial transparent dressings. Results The chlorhexidine gluconate dressing prevents 11.8 infections /1,000 patients (95% confidence interval: [3.85; 19.64]) with a number needed to treat of 85 patients. The mean cost difference per patient of €141 is not statistically significant (95% confidence interval: [€-975; €1,258]). The incremental cost-effectiveness ratio is of €12,046 per catheter-related bloodstream infection prevented, and the incremental net monetary benefit per patient is of €344.88. Conclusions According to the base case scenario, the chlorhexidine gluconate dressing is more cost-effective than the reference dressing. Trial Registration This model is based on the data from the RCT registered with www.clinicaltrials.gov (NCT01189682). PMID:26086783

Final CSAPR Revisions Rule (77 FR 10324)

EPA Pesticide Factsheets

EPA finalizes revisions to the Transport Rule (76 FR 48208). These revisions address discrepancies in unit-specific modeling assumptions that affect the proper calculation of Transport Rule state budgets and assurance levels in several states.

77 FR 64189 - Changes to Representation of Others Before the United States Patent and Trademark Office

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-18

...The United States Patent and Trademark Office (Office or USPTO) proposes to align the USPTO's professional responsibility rules with those of most other U.S. jurisdictions by replacing the current Patent and Trademark Office Code of Professional Responsibility, adopted in 1985, based on the 1980 version of the Model Code of Professional Responsibility of the American Bar Association (``ABA''), with new USPTO Rules of Professional Conduct, which are based on the Model Rules of Professional Conduct of the ABA, which were published in 1983, substantially revised in 2003 and updated through 2011. Changes approved by the ABA House of Delegates in August 2012 have not been incorporated in these proposed rules. The Office also proposes to revise the existing procedural rules governing disciplinary investigations and proceedings.

Comparative Analysis of Reduced-Rule Compressed Fuzzy Logic Control and Incremental Conductance MPPT Methods

NASA Astrophysics Data System (ADS)

Kandemir, Ekrem; Borekci, Selim; Cetin, Numan S.

2018-04-01

Photovoltaic (PV) power generation has been widely used in recent years, with techniques for increasing the power efficiency representing one of the most important issues. The available maximum power of a PV panel is dependent on environmental conditions such as solar irradiance and temperature. To extract the maximum available power from a PV panel, various maximum-power-point tracking (MPPT) methods are used. In this work, two different MPPT methods were implemented for a 150-W PV panel. The first method, known as incremental conductance (Inc. Cond.) MPPT, determines the maximum power by measuring the derivative of the PV voltage and current. The other method is based on reduced-rule compressed fuzzy logic control (RR-FLC), using which it is relatively easier to determine the maximum power because a single input variable is used to reduce computing loads. In this study, a 150-W PV panel system model was realized using these MPPT methods in MATLAB and the results compared. According to the simulation results, the proposed RR-FLC-based MPPT could increase the response rate and tracking accuracy by 4.66% under standard test conditions.

40 CFR 60.2590 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2590 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2012 CFR

2012-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2830 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2590 - When must I submit the notifications of achievement of increments of progress?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2845 - How do I comply with the increment of progress for achieving final compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2605 - How do I comply with the increment of progress for achieving final compliance?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2605 - How do I comply with the increment of progress for achieving final compliance?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

Development of constitutive models for cyclic plasticity and creep behavior of super alloys at high temperature

NASA Technical Reports Server (NTRS)

Haisler, W. E.

1983-01-01

An uncoupled constitutive model for predicting the transient response of thermal and rate dependent, inelastic material behavior was developed. The uncoupled model assumes that there is a temperature below which the total strain consists essentially of elastic and rate insensitive inelastic strains only. Above this temperature, the rate dependent inelastic strain (creep) dominates. The rate insensitive inelastic strain component is modelled in an incremental form with a yield function, blow rule and hardening law. Revisions to the hardening rule permit the model to predict temperature-dependent kinematic-isotropic hardening behavior, cyclic saturation, asymmetric stress-strain response upon stress reversal, and variable Bauschinger effect. The rate dependent inelastic strain component is modelled using a rate equation in terms of back stress, drag stress and exponent n as functions of temperature and strain. A sequence of hysteresis loops and relaxation tests are utilized to define the rate dependent inelastic strain rate. Evaluation of the model has been performed by comparison with experiments involving various thermal and mechanical load histories on 5086 aluminum alloy, 304 stainless steel and Hastelloy X.

Interfacial welding of dynamic covalent network polymers

NASA Astrophysics Data System (ADS)

Yu, Kai; Shi, Qian; Li, Hao; Jabour, John; Yang, Hua; Dunn, Martin L.; Wang, Tiejun; Qi, H. Jerry

2016-09-01

Dynamic covalent network (or covalent adaptable network) polymers can rearrange their macromolecular chain network by bond exchange reactions (BERs) where an active unit replaces a unit in an existing bond to form a new bond. Such macromolecular events, when they occur in large amounts, can attribute to unusual properties that are not seen in conventional covalent network polymers, such as shape reforming and surface welding; the latter further enables the important attributes of material malleability and powder-based reprocessing. In this paper, a multiscale modeling framework is developed to study the surface welding of thermally induced dynamic covalent network polymers. At the macromolecular network level, a lattice model is developed to describe the chain density evolution across the interface and its connection to bulk stress relaxation due to BERs. The chain density evolution rule is then fed into a continuum level interfacial model that takes into account surface roughness and applied pressure to predict the effective elastic modulus and interfacial fracture energy of welded polymers. The model yields particularly accessible results where the moduli and interfacial strength of the welded samples as a function of temperature and pressure can be predicted with four parameters, three of which can be measured directly. The model identifies the dependency of surface welding efficiency on the applied thermal and mechanical fields: the pressure will affect the real contact area under the consideration of surface roughness of dynamic covalent network polymers; the chain density increment on the real contact area of interface is only dependent on the welding time and temperature. The modeling approach shows good agreement with experiments and can be extended to other types of dynamic covalent network polymers using different stimuli for BERs, such as light and moisture etc.

40 CFR 52.270 - Significant deterioration of air quality.

Code of Federal Regulations, 2013 CFR

2013-07-01

... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

40 CFR 52.270 - Significant deterioration of air quality.

Code of Federal Regulations, 2012 CFR

2012-07-01

... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

40 CFR 52.270 - Significant deterioration of air quality.

Code of Federal Regulations, 2011 CFR

2011-07-01

... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

40 CFR 52.270 - Significant deterioration of air quality.

Code of Federal Regulations, 2014 CFR

2014-07-01

... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

40 CFR 60.2560 - What is the “model rule” in this subpart?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Use of Model Rule § 60.2560 What is the “model rule” in this subpart? (a) The model rule is the portion of these emission...

40 CFR 60.2560 - What is the “model rule” in this subpart?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Use of Model Rule § 60.2560 What is the “model rule” in this subpart? (a) The model rule is the portion of these emission...

40 CFR 60.2560 - What is the “model rule” in this subpart?

Code of Federal Regulations, 2012 CFR

2012-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Use of Model Rule § 60.2560 What is the “model rule” in this subpart? (a) The model rule is the portion of these emission...

Cost-effectiveness of vedolizumab compared with infliximab, adalimumab, and golimumab in patients with ulcerative colitis in the United Kingdom.

PubMed

Wilson, Michele R; Bergman, Annika; Chevrou-Severac, Helene; Selby, Ross; Smyth, Michael; Kerrigan, Matthew C

2018-03-01

To examine the clinical and economic impact of vedolizumab compared with infliximab, adalimumab, and golimumab in the treatment of moderately to severely active ulcerative colitis (UC) in the United Kingdom (UK). A decision analytic model in Microsoft Excel was used to compare vedolizumab with other biologic treatments (infliximab, adalimumab, and golimumab) for the treatment of biologic-naïve patients with UC in the UK. Efficacy data were obtained from a network meta-analysis using placebo as the common comparator. Other inputs (e.g., unit costs, adverse-event disutilities, probability of surgery, mortality) were obtained from published literature. Costs were presented in 2012/2013 British pounds. Outcomes included quality-adjusted life-years (QALYs). Costs and outcomes were discounted by 3.5% per year. Incremental cost-effectiveness ratios were presented for vedolizumab compared with other biologics. Univariate and multivariate probabilistic sensitivity analyses were conducted to assess model robustness to parameter uncertainty. The model predicted that anti-tumour necrosis factor-naïve patients on vedolizumab would accrue more QALY than patients on other biologics. The incremental results suggest that vedolizumab is a cost-effective treatment compared with adalimumab (incremental cost-effectiveness ratio of £22,735/QALY) and dominant compared with infliximab and golimumab. Sensitivity analyses suggest that results are most sensitive to treatment response and transition probabilities. However, vedolizumab is cost-effective irrespective of variation in any of the input parameters. Our model predicted that treatment with vedolizumab improves QALY, increases time in remission and response, and is a cost-effective treatment option compared with all other biologics for biologic-naïve patients with moderately to severely active UC.

Particle filters, a quasi-Monte-Carlo-solution for segmentation of coronaries.

PubMed

Florin, Charles; Paragios, Nikos; Williams, Jim

2005-01-01

In this paper we propose a Particle Filter-based approach for the segmentation of coronary arteries. To this end, successive planes of the vessel are modeled as unknown states of a sequential process. Such states consist of the orientation, position, shape model and appearance (in statistical terms) of the vessel that are recovered in an incremental fashion, using a sequential Bayesian filter (Particle Filter). In order to account for bifurcations and branchings, we consider a Monte Carlo sampling rule that propagates in parallel multiple hypotheses. Promising results on the segmentation of coronary arteries demonstrate the potential of the proposed approach.

Development and Evaluation of an Uncoupled, Incremental Constitutive Model for Elastic-Plastic-Creep Behavior at Elevated Temperatures.

DTIC Science & Technology

1982-05-01

Pugh, C. E., "Creep Studies on Type 304 Stainless Steel (Heat 8043813) Under Constant and Varying Loads," ORNL -TM- 4427 , June 1974, Oak Ridge National...34 hysteria loop predictions show. Oak Ridge ( ORNL ) [30) and combined hardening rules predict overall * 21 Stes Stress...Analysis of FFTF Components," ORNL TM-3602, Oak Ridge National Laboratory, Oak Ridge, Tenn., Sept. 1972. 31. Dafalias, Y. F., and Popov, E. P., "Plastic

40 CFR 60.2600 - How do I comply with the increment of progress for submittal of a control plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2600 - How do I comply with the increment of progress for submittal of a control plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2840 - How do I comply with the increment of progress for submittal of a control plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

40 CFR 60.2600 - How do I comply with the increment of progress for submittal of a control plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model...

78 FR 17304 - Approval and Promulgation of Implementation Plans; Oregon: Infrastructure Requirements for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-21

... Products Industries OAR 340-236 Emission Standards for Specific Industries OAR 340-240 Rules for Areas with... and PSD Increments'' includes the 1997 PM 2.5 , 2006 PM 2.5 , and 2008 ozone NAAQS. The EPA most... addition to other rules and control programs identified below. The EPA most recently approved revisions to...

78 FR 136 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... Proposed Rule Change Relating to Extension of the Exchange's Penny Pilot Program and Replacement of Penny... VI, Section 5 (Minimum Increments) of the rules of NOM to: extend through June 30, 2013, the Penny Pilot Program in options classes in certain issues (``Penny Pilot'' or ``Pilot''), and to change the...

78 FR 73909 - Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-09

... Effectiveness of Proposed Rule Change To Extend the Penny Pilot Program December 3, 2013. Pursuant to Section 19... certain options in pennies (the ``Penny Pilot Program''). The text of the proposed rule change is... quoting and trading of certain option classes in penny increments (the ``Penny Pilot Program'' or...

40 CFR 60.1570 - What is the “model rule” in this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Use of Model Rule § 60.1570 What is the “model rule” in this subpart? (a) The model rule is the portion of the...

40 CFR 60.5070 - What is the “model rule” in this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Use of Model Rule § 60.5070 What is the “model rule” in this subpart? (a) The model rule is the portion of these emission guidelines (§§ 60.5085 through...

Space Fence Ground-Based Radar System Increment 1 (Space Fence Inc 1)

DTIC Science & Technology

2015-12-01

Net - Centric Data Strategy and Net-Centric Services Strategy, and the principles and rules identified in the DoD IEA, excepting tactical and...Centric Data Strategy and Net- Centric Services Strategy, and the principles and rules identified in the DoD IEA, excepting tactical and non-IP...Strategy, and the principles and rules identified in the DoD IEA, excepting tactical and non-IP communi- cations. Compliant with TBD Space Fence must

Algorithm Optimally Orders Forward-Chaining Inference Rules

NASA Technical Reports Server (NTRS)

James, Mark

2008-01-01

People typically develop knowledge bases in a somewhat ad hoc manner by incrementally adding rules with no specific organization. This often results in a very inefficient execution of those rules since they are so often order sensitive. This is relevant to tasks like Deep Space Network in that it allows the knowledge base to be incrementally developed and have it automatically ordered for efficiency. Although data flow analysis was first developed for use in compilers for producing optimal code sequences, its usefulness is now recognized in many software systems including knowledge-based systems. However, this approach for exhaustively computing data-flow information cannot directly be applied to inference systems because of the ubiquitous execution of the rules. An algorithm is presented that efficiently performs a complete producer/consumer analysis for each antecedent and consequence clause in a knowledge base to optimally order the rules to minimize inference cycles. An algorithm was developed that optimally orders a knowledge base composed of forwarding chaining inference rules such that independent inference cycle executions are minimized, thus, resulting in significantly faster execution. This algorithm was integrated into the JPL tool Spacecraft Health Inference Engine (SHINE) for verification and it resulted in a significant reduction in inference cycles for what was previously considered an ordered knowledge base. For a knowledge base that is completely unordered, then the improvement is much greater.

A study on the uniqueness of the plastic flow direction for granular assemblies of ductile particles using discrete finite-element simulations

NASA Astrophysics Data System (ADS)

Abdelmoula, Nouha; Harthong, Barthélémy; Imbault, Didier; Dorémus, Pierre

2017-12-01

The multi-particle finite element method involving assemblies of meshed particles interacting through finite-element contact conditions is adopted to study the plastic flow of a granular material with highly deformable elastic-plastic grains. In particular, it is investigated whether the flow rule postulate applies for such materials. Using a spherical stress probing method, the influence of incremental stress on plastic strain increment vectors was assessed for numerical samples compacted along two different loading paths up to different values of relative density. Results show that the numerical samples studied behave reasonably well according to an associated flow rule, except in the vicinity of the loading point where the influence of the stress increment proved to be very significant. A plausible explanation for the non-uniqueness of the direction of plastic flow is proposed, based on the idea that the resistance of the numerical sample to plastic straining can vary by an order of magnitude depending on the direction of the accumulated stress. The above-mentioned dependency of the direction of plastic flow on the direction of the stress increment was related to the difference in strength between shearing and normal stressing at the scale of contact surfaces between particles.

Stable Isotope Analysis of Extant Lamnoid Shark Centra: A New Tool in Age Determination?

NASA Astrophysics Data System (ADS)

Labs, J.

2003-12-01

The oxygen isotopes of fourteen vertebral centra from ten extant lamnoid sharks (including Carcharodon carcharias [great white], Isurus paucus [longfin mako], and Isurus oxyrinchus [shortfin mako]) were sampled and measured along the growth axis to determine the periodicity of incremental growth represented in the centra. As part of the internal (endochondral) skeleton, shark centra are composed initially of hyaline cartilage, which then secondarily ossifies during ontogeny forming calcified hydroxyapatite bone. The incremental growth of shark centra forms definite growth rings, with darker denser portions being deposited during slower growth times (i.e., winter) and lighter portions being deposited during more rapid growth (i.e., summer). Thus, shark centra, whether they are extant or extinct, are characterized by clearly delineated incremental growth couplets. The problem with this general rule is that there are several factors in which the growth of these couplets can vary depending upon physical environment (including temperature and water depth), food availability, and stress. The challenge for paleobiological interpretations is how to interpret the periodicity of this growth. It can generally be assumed that these bands are annual, but it is uncertain the extent to which exceptions to the rule occur. Stable isotopic analysis provides the potential to independently determine the periodicity of the growth increments and ultimately the ontogenetic age of an individual.

Strategies for adding adaptive learning mechanisms to rule-based diagnostic expert systems

NASA Technical Reports Server (NTRS)

Stclair, D. C.; Sabharwal, C. L.; Bond, W. E.; Hacke, Keith

1988-01-01

Rule-based diagnostic expert systems can be used to perform many of the diagnostic chores necessary in today's complex space systems. These expert systems typically take a set of symptoms as input and produce diagnostic advice as output. The primary objective of such expert systems is to provide accurate and comprehensive advice which can be used to help return the space system in question to nominal operation. The development and maintenance of diagnostic expert systems is time and labor intensive since the services of both knowledge engineer(s) and domain expert(s) are required. The use of adaptive learning mechanisms to increment evaluate and refine rules promises to reduce both time and labor costs associated with such systems. This paper describes the basic adaptive learning mechanisms of strengthening, weakening, generalization, discrimination, and discovery. Next basic strategies are discussed for adding these learning mechanisms to rule-based diagnostic expert systems. These strategies support the incremental evaluation and refinement of rules in the knowledge base by comparing the set of advice given by the expert system (A) with the correct diagnosis (C). Techniques are described for selecting those rules in the in the knowledge base which should participate in adaptive learning. The strategies presented may be used with a wide variety of learning algorithms. Further, these strategies are applicable to a large number of rule-based diagnostic expert systems. They may be used to provide either immediate or deferred updating of the knowledge base.

A rule-based, dose-finding design for use in stroke rehabilitation research: methodological development.

PubMed

Colucci, E; Clark, A; Lang, C E; Pomeroy, V M

2017-12-01

Dose-optimisation studies as precursors to clinical trials are rare in stroke rehabilitation. To develop a rule-based, dose-finding design for stroke rehabilitation research. 3+3 rule-based, dose-finding study. Dose escalation/de-escalation was undertaken according to preset rules and a mathematical sequence (modified Fibonacci sequence). The target starting daily dose was 50 repetitions for the first cohort. Adherence was recorded by an electronic counter. At the end of the 2-week training period, the adherence record indicated dose tolerability (adherence to target dose) and the outcome measure indicated dose benefit (10% increase in motor function). The preset increment/decrease and checking rules were then applied to set the dose for the subsequent cohort. The process was repeated until preset stopping rules were met. Participants had a mean age of 68 (range 48 to 81) years, and were a mean of 70 (range 9 to 289) months post stroke with moderate upper limb paresis. A custom-built model of exercise-based training to enhance ability to open the paretic hand. Repetitions per minute of extension/flexion of paretic digits against resistance. Usability of the preset rules and whether the maximally tolerated dose was identifiable. Five cohorts of three participants were involved. Discernibly different doses were set for each subsequent cohort (i.e. 50, 100, 167, 251 and 209 repetitions/day). The maximally tolerated dose for the model training task was 209 repetitions/day. This dose-finding design is a feasible method for use in stroke rehabilitation research. Copyright © 2017 Chartered Society of Physiotherapy. All rights reserved.

SU-F-T-74: Experimental Validation of Monaco Electron Monte Carlo Dose Calculation for Small Fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Varadhan; Way, S; Arentsen, L

2016-06-15

Purpose: To verify experimentally the accuracy of Monaco (Elekta) electron Monte Carlo (eMC) algorithm to calculate small field size depth doses, monitor units and isodose distributions. Methods: Beam modeling of eMC algorithm was performed for electron energies of 6, 9, 12 15 and 18 Mev for a Elekta Infinity Linac and all available ( 6, 10, 14 20 and 25 cone) applicator sizes. Electron cutouts of incrementally smaller field sizes (20, 40, 60 and 80% blocked from open cone) were fabricated. Dose calculation was performed using a grid size smaller than one-tenth of the R{sub 80–20} electron distal falloff distancemore » and number of particle histories was set at 500,000 per cm{sup 2}. Percent depth dose scans and beam profiles at dmax, d{sub 90} and d{sub 80} depths were measured for each cutout and energy with Wellhoffer (IBA) Blue Phantom{sup 2} scanning system and compared against eMC calculated doses. Results: The measured dose and output factors of incrementally reduced cutout sizes (to 3cm diameter) agreed with eMC calculated doses within ± 2.5%. The profile comparisons at dmax, d{sub 90} and d{sub 80} depths and percent depth doses at reduced field sizes agreed within 2.5% or 2mm. Conclusion: Our results indicate that the Monaco eMC algorithm can accurately predict depth doses, isodose distributions, and monitor units in homogeneous water phantom for field sizes as small as 3.0 cm diameter for energies in the 6 to 18 MeV range at 100 cm SSD. Consequently, the old rule of thumb to approximate limiting cutout size for an electron field determined by the lateral scatter equilibrium (E (MeV)/2.5 in centimeters of water) does not apply to Monaco eMC algorithm.« less

Presenting Germany's drug pricing rule as a cost-per-QALY rule.

PubMed

Gandjour, Afschin

2012-06-01

In Germany, the Institute for Quality and Efficiency in Health Care (IQWiG) makes recommendations for ceiling prices of drugs based on an evaluation of the relationship between costs and effectiveness. To set ceiling prices, IQWiG uses the following decision rule: the incremental cost-effectiveness ratio of a new drug compared with the next effective intervention should not be higher than that of the next effective intervention compared to its comparator. The purpose of this paper is to show that IQWiG's decision rule can be presented as a cost-per-QALY rule by using equity-weighted QALYs. This transformation shows where both rules share commonalities. Furthermore, it makes the underlying ethical implications of IQWiG's decision rule transparent and open to debate.

Demonstration/Validation of Incremental Sampling at Two Diverse Military Ranges and Development of an Incremental Sampling Tool

DTIC Science & Technology

2010-06-01

Sampling (MIS)? • Technique of combining many increments of soil from a number of points within exposure area • Developed by Enviro Stat (Trademarked...Demonstrating a reliable soil sampling strategy to accurately characterize contaminant concentrations in spatially extreme and heterogeneous...into a set of decision (exposure) units • One or several discrete or small- scale composite soil samples collected to represent each decision unit

On the search for an appropriate metric for reaction time to suprathreshold increments and decrements.

PubMed

Vassilev, Angel; Murzac, Adrian; Zlatkova, Margarita B; Anderson, Roger S

2009-03-01

Weber contrast, DeltaL/L, is a widely used contrast metric for aperiodic stimuli. Zele, Cao & Pokorny [Zele, A. J., Cao, D., & Pokorny, J. (2007). Threshold units: A correct metric for reaction time? Vision Research, 47, 608-611] found that neither Weber contrast nor its transform to detection-threshold units equates human reaction times in response to luminance increments and decrements under selective rod stimulation. Here we show that their rod reaction times are equated when plotted against the spatial luminance ratio between the stimulus and its background (L(max)/L(min), the larger and smaller of background and stimulus luminances). Similarly, reaction times to parafoveal S-cone selective increments and decrements from our previous studies [Murzac, A. (2004). A comparative study of the temporal characteristics of processing of S-cone incremental and decremental signals. PhD thesis, New Bulgarian University, Sofia, Murzac, A., & Vassilev, A. (2004). Reaction time to S-cone increments and decrements. In: 7th European conference on visual perception, Budapest, August 22-26. Perception, 33, 180 (Abstract).], are better described by the spatial luminance ratio than by Weber contrast. We assume that the type of stimulus detection by temporal (successive) luminance discrimination, by spatial (simultaneous) luminance discrimination or by both [Sperling, G., & Sondhi, M. M. (1968). Model for visual luminance discrimination and flicker detection. Journal of the Optical Society of America, 58, 1133-1145.] determines the appropriateness of one or other contrast metric for reaction time.

Application of an Uncoupled Elastic-plastic-creep Constitutive Model to Metals at High Temperature

NASA Technical Reports Server (NTRS)

Haisler, W. E.

1983-01-01

A uniaxial, uncoupled constitutive model to predict the response of thermal and rate dependent elastic-plastic material behavior is presented. The model is based on an incremental classicial plasticity theory extended to account for thermal, creep, and transient temperature conditions. Revisions to he combined hardening rule of the theory allow for better representation of cyclic phenomenon including the high rate of strain hardening upon cyclic reyield and cyclic saturation. An alternative approach is taken to model the rate dependent inelastic deformation which utilizes hysteresis loops and stress relaxation test data at various temperatures. The model is evaluated and compared to experiments which involve various thermal and mechanical load histories on 5086 aluminum alloy, 304 stainless steel and Hastelloy-X.

Back to the Future: Consistency-Based Trajectory Tracking

NASA Technical Reports Server (NTRS)

Kurien, James; Nayak, P. Pandurand; Norvig, Peter (Technical Monitor)

2000-01-01

Given a model of a physical process and a sequence of commands and observations received over time, the task of an autonomous controller is to determine the likely states of the process and the actions required to move the process to a desired configuration. We introduce a representation and algorithms for incrementally generating approximate belief states for a restricted but relevant class of partially observable Markov decision processes with very large state spaces. The algorithm presented incrementally generates, rather than revises, an approximate belief state at any point by abstracting and summarizing segments of the likely trajectories of the process. This enables applications to efficiently maintain a partial belief state when it remains consistent with observations and revisit past assumptions about the process' evolution when the belief state is ruled out. The system presented has been implemented and results on examples from the domain of spacecraft control are presented.

77 FR 34108 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-08

...(b) and (c), Rule 1034 and Rule 1038 do not apply to orders placed in the cabinet. Cabinet... June 1, 2012.\\10\\ On April 27, 2012, the Exchange filed for permanent approval of the temporary... limited to options classes traded in $0.05 or $0.10 standard increments. The $1 cabinet trading procedures...

78 FR 77538 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-23

... (c), Rule 1034 and Rule 1038 do not apply to orders placed in the cabinet. Cabinet transactions are... Exchange filed an immediately effective proposal that extended the pilot program until December 1, 2012.\\10... procedures were limited to options classes traded in $0.05 or $0.10 standard increments. The $1 cabinet...

26 CFR 1.72-17A - Special rules applicable to employee annuities and distributions under deferred compensation...

Code of Federal Regulations, 2014 CFR

2014-04-01

..., 1974. Paragraph (e) of this section provides rules for penalties provided by section 72(m)(5) with...-employees under section 72(m)(5). (1)(i) For taxable years of the recipient beginning after December 31... (that is employer contributions within the meaning of section 401(c)(5)(A) and the increments in value...

26 CFR 1.72-17A - Special rules applicable to employee annuities and distributions under deferred compensation...

Code of Federal Regulations, 2013 CFR

2013-04-01

..., 1974. Paragraph (e) of this section provides rules for penalties provided by section 72(m)(5) with...-employees under section 72(m)(5). (1)(i) For taxable years of the recipient beginning after December 31... (that is employer contributions within the meaning of section 401(c)(5)(A) and the increments in value...

26 CFR 1.72-17A - Special rules applicable to employee annuities and distributions under deferred compensation...

Code of Federal Regulations, 2012 CFR

2012-04-01

..., 1974. Paragraph (e) of this section provides rules for penalties provided by section 72(m)(5) with...-employees under section 72(m)(5). (1)(i) For taxable years of the recipient beginning after December 31... (that is employer contributions within the meaning of section 401(c)(5)(A) and the increments in value...

26 CFR 1.72-17A - Special rules applicable to employee annuities and distributions under deferred compensation...

Code of Federal Regulations, 2011 CFR

2011-04-01

..., 1974. Paragraph (e) of this section provides rules for penalties provided by section 72(m)(5) with...-employees under section 72(m)(5). (1)(i) For taxable years of the recipient beginning after December 31... (that is employer contributions within the meaning of section 401(c)(5)(A) and the increments in value...

26 CFR 1.72-17A - Special rules applicable to employee annuities and distributions under deferred compensation...

Code of Federal Regulations, 2010 CFR

2010-04-01

..., 1974. Paragraph (e) of this section provides rules for penalties provided by section 72(m)(5) with...-employees under section 72(m)(5). (1)(i) For taxable years of the recipient beginning after December 31... (that is employer contributions within the meaning of section 401(c)(5)(A) and the increments in value...

Evolution of cooperation driven by incremental learning

NASA Astrophysics Data System (ADS)

Li, Pei; Duan, Haibin

2015-02-01

It has been shown that the details of microscopic rules in structured populations can have a crucial impact on the ultimate outcome in evolutionary games. So alternative formulations of strategies and their revision processes exploring how strategies are actually adopted and spread within the interaction network need to be studied. In the present work, we formulate the strategy update rule as an incremental learning process, wherein knowledge is refreshed according to one's own experience learned from the past (self-learning) and that gained from social interaction (social-learning). More precisely, we propose a continuous version of strategy update rules, by introducing the willingness to cooperate W, to better capture the flexibility of decision making behavior. Importantly, the newly gained knowledge including self-learning and social learning is weighted by the parameter ω, establishing a strategy update rule involving innovative element. Moreover, we quantify the macroscopic features of the emerging patterns to inspect the underlying mechanisms of the evolutionary process using six cluster characteristics. In order to further support our results, we examine the time evolution course for these characteristics. Our results might provide insights for understanding cooperative behaviors and have several important implications for understanding how individuals adjust their strategies under real-life conditions.

Longitudinal associations between dental caries increment and risk factors in late childhood and adolescence.

PubMed

Curtis, Alexandra M; VanBuren, John; Cavanaugh, Joseph E; Warren, John J; Marshall, Teresa A; Levy, Steven M

2018-05-12

To assess longitudinal associations between permanent tooth caries increment and both modifiable and non-modifiable risk factors, using best subsets model selection. The Iowa Fluoride Study has followed a birth cohort with standardized caries exams without radiographs of the permanent dentition conducted at about ages 9, 13, and 17 years. Questionnaires were sent semi-annually to assess fluoride exposures and intakes, select food and beverage intakes, and tooth brushing frequency. Exposure variables were averaged over ages 7-9, 11-13, and 15-17, reflecting exposure 2 years prior to the caries exam. Longitudinal models were used to relate period-specific averaged exposures and demographic variables to adjusted decayed and filled surface increments (ADJCI) (n = 392). The Akaike Information Criterion (AIC) was used to assess optimal explanatory variable combinations. From birth to age 9, 9-13, and 13-17 years, 24, 30, and 55 percent of subjects had positive permanent ADJCI, respectively. Ten models had AIC values within two units of the lowest AIC model and were deemed optimal based on AIC. Younger age, being male, higher mother's education, and higher brushing frequency were associated with lower caries increment in all 10 models, while milk intake was included in 3 of 10 models. Higher milk intakes were slightly associated with lower ADJCI. With the exception of brushing frequency, modifiable risk factors under study were not significantly associated with ADJCI. When possible, researchers should consider presenting multiple models if fit criteria cannot discern among a group of optimal models. © 2018 American Association of Public Health Dentistry.

Incremental value of the CT coronary calcium score for the prediction of coronary artery disease

PubMed Central

Genders, Tessa S. S.; Pugliese, Francesca; Mollet, Nico R.; Meijboom, W. Bob; Weustink, Annick C.; van Mieghem, Carlos A. G.; de Feyter, Pim J.

2010-01-01

Objectives: To validate published prediction models for the presence of obstructive coronary artery disease (CAD) in patients with new onset stable typical or atypical angina pectoris and to assess the incremental value of the CT coronary calcium score (CTCS). Methods: We searched the literature for clinical prediction rules for the diagnosis of obstructive CAD, defined as ≥50% stenosis in at least one vessel on conventional coronary angiography. Significant variables were re-analysed in our dataset of 254 patients with logistic regression. CTCS was subsequently included in the models. The area under the receiver operating characteristic curve (AUC) was calculated to assess diagnostic performance. Results: Re-analysing the variables used by Diamond & Forrester yielded an AUC of 0.798, which increased to 0.890 by adding CTCS. For Pryor, Morise 1994, Morise 1997 and Shaw the AUC increased from 0.838 to 0.901, 0.831 to 0.899, 0.840 to 0.898 and 0.833 to 0.899. CTCS significantly improved model performance in each model. Conclusions: Validation demonstrated good diagnostic performance across all models. CTCS improves the prediction of the presence of obstructive CAD, independent of clinical predictors, and should be considered in its diagnostic work-up. PMID:20559838

Mechanical Behaviour of Light Metal Alloys at High Strain Rates. Computer Simulation on Mesoscale Levels

NASA Astrophysics Data System (ADS)

Skripnyak, Vladimir; Skripnyak, Evgeniya; Meyer, Lothar W.; Herzig, Norman; Skripnyak, Nataliya

2012-02-01

Researches of the last years have allowed to establish that the laws of deformation and fracture of bulk ultrafine-grained and coarse-grained materials are various both in static and in dynamic loading conditions. Development of adequate constitutive equations for the description of mechanical behavior of bulk ultrafine-grained materials at intensive dynamic influences is complicated in consequence of insufficient knowledge about general rules of inelastic deformation and nucleation and growth of cracks. Multi-scale computational model was used for the investigation of deformation and fracture of bulk structured aluminum and magnesium alloys under stress pulse loadings on mesoscale level. The increment of plastic deformation is defined by the sum of the increments caused by a nucleation and gliding of dislocations, the twinning, meso-blocks movement, and grain boundary sliding. The model takes into account the influence on mechanical properties of alloys an average grains size, grain sizes distribution of and concentration of precipitates. It was obtained the nucleation and gliding of dislocations caused the high attenuation rate of the elastic precursor of ultrafine-grained alloys than in coarse grained counterparts.

Plutons: Simmer between 350° and 500°C for 10 million years, then serve cold (Invited)

NASA Astrophysics Data System (ADS)

Coleman, D. S.; Davis, J.

2009-12-01

The growing recognition that continental plutons are assembled incrementally over millions of years requires reexamination of the thermal histories of intrusive rocks. With the exception of the suggestion that pluton magma chambers can be revitalized by mafic input at their deepest structural levels, most aspects of modern pluton petrology are built on the underlying assumption that silicic plutons intrude as discrete thermal packages that undergo subsequent monotonic decay back to a steady-state geothermal gradient. The recognition that homogeneous silicic plutons are constructed over timescales too great to be single events necessitates rethinking pluton intrusion mechanisms, textures, thermochronology, chemical evolution and links to volcanic rocks. Three-dimensional thermal modeling of sheeted (horizontal and vertical) incremental pluton assembly (using HEAT3D by Wohletz, 2007) yields several results that are largely independent of intrusive geometry and may help understand bothersome field and laboratory results from plutonic rocks. 1) All increments cool quickly below hornblende closure temperature. However, late increments are emplaced into walls warmed by earlier increments, and they cycle between hornblende and biotite closure temperatures, a range in which fluid-rich melts are likely to be present. These conditions persist until the increments are far from the region of new magma flux, or the addition of increments stops. These observations are supported by Ar thermochronology and may explain why heterogeneous early marginal intrusive phases often grade into younger homogeneous interior map units. 2) Early increments become the contact metamorphic wall rocks of later increments. This observation suggests that much of the contact metamorphism associated with a given volume of plutonic rock is “lost” via textural modification of early increments during intrusion of later increments. Johnson and Glazner (CMP, in press) argue that mappable variations in pluton texture can result from textural modification during thermal cycling associated with incremental assembly. 3) The thermal structure of the model pluton evolves toward roughly spheroidal isotherms even though the pluton is assembled from thin tabular sheets. The zone of melt-bearing rock and the shape of intrapluton contact metamorphic isograds bear little resemblance to the increments from which the pluton was built. Consequently, pluton contacts mapped by variations in texture that reflect the thermal cycling inherent to incremental assembly will inevitably be “blob” or diapir-like, but will yield little insight into magma intrusion geometry. 4) Although models yield large regions of melt-bearing rock, the melt fraction is low and the melt-bearing volume at any time is small compared to the total volume of the pluton. This observation raises doubts about the connections between zoned silicic plutons and large ignimbrite eruptions.

Dissolved Solids in Streams of the Conterminous United States

NASA Astrophysics Data System (ADS)

Anning, D. W.; Flynn, M.

2014-12-01

Studies have shown that excessive dissolved-solids concentrations in water can have adverse effects on the environment and on agricultural, municipal, and industrial water users. Such effects motivated the U.S. Geological Survey's National Water-Quality Assessment Program to develop a SPAtially-Referenced Regression on Watershed Attributes (SPARROW) model to improve the understanding of dissolved solids in streams of the United States. Using the SPARROW model, annual dissolved-solids loads from 2,560 water-quality monitoring stations were statistically related to several spatial datasets serving as surrogates for dissolved-solids sources and transport processes. Sources investigated in the model included geologic materials, road de-icers, urban lands, cultivated lands, and pasture lands. Factors affecting transport from these sources to streams in the model included climate, soil, vegetation, terrain, population, irrigation, and artificial-drainage characteristics. The SPARROW model was used to predict long-term mean annual conditions for dissolved-solids sources, loads, yields, and concentrations in about 66,000 stream reaches and corresponding incremental catchments nationwide. The estimated total amount of dissolved solids delivered to the Nation's streams is 272 million metric tons (Mt) annually, of which 194 million Mt (71%) are from geologic sources, 38 million Mt (14%) are from road de-icers, 18 million Mt (7%) are from pasture lands, 14 million Mt (5 %) are from urban lands, and 8 million Mt (3%) are from cultivated lands. The median incremental-catchment yield delivered to local streams is 26 metric tons per year per square kilometer [(Mt/yr)/km2]. Ten percent of the incremental catchments yield less than 4 (Mt/yr)/km2, and 10 percent yield more than 90 (Mt/yr)/km2. In 13% of the reaches, predicted flow-weighted concentrations exceed 500 mg/L—the U.S. Environmental Protection Agency secondary non-enforceable drinking-water standard.

Flight Rules Critical Readiness Review

NASA Technical Reports Server (NTRS)

Kim, E.; Knudsen, F.; Rice, S.

2010-01-01

The increment 23/24 Critical Readiness Review (CRR) flight rules are presented. The topics include: 1) B13-152 Acoustic Constraints; 2) B13-113 IFM/Corrective Action Prioritization Due to Loss of Exercise Capability; 3) B13-116 Constraints on Treadmill VIS Failure; 4) B13-201 Medical Management of ISS Fire/Smoke Response; 5) ARED and T2 Exercise constraints Flight rules (flight and stage specific); 6) FYI: B14 FR to be updated with requirement to sample crew sleep locations prior to receiving a "recommendation" from SRAG on where to sleep.

An Incremental High-Utility Mining Algorithm with Transaction Insertion

PubMed Central

Gan, Wensheng; Zhang, Binbin

2015-01-01

Association-rule mining is commonly used to discover useful and meaningful patterns from a very large database. It only considers the occurrence frequencies of items to reveal the relationships among itemsets. Traditional association-rule mining is, however, not suitable in real-world applications since the purchased items from a customer may have various factors, such as profit or quantity. High-utility mining was designed to solve the limitations of association-rule mining by considering both the quantity and profit measures. Most algorithms of high-utility mining are designed to handle the static database. Fewer researches handle the dynamic high-utility mining with transaction insertion, thus requiring the computations of database rescan and combination explosion of pattern-growth mechanism. In this paper, an efficient incremental algorithm with transaction insertion is designed to reduce computations without candidate generation based on the utility-list structures. The enumeration tree and the relationships between 2-itemsets are also adopted in the proposed algorithm to speed up the computations. Several experiments are conducted to show the performance of the proposed algorithm in terms of runtime, memory consumption, and number of generated patterns. PMID:25811038

Estimating tree grades for Southern Appalachian natural forest stands

Treesearch

Jeffrey P. Prestemon

1998-01-01

Log prices can vary significantly by grade: grade 1 logs are often several times the price per unit of grade 3 logs. Because tree grading rules derive from log grading rules, a model that predicts tree grades based on tree and stand-level variables might be useful for predicting stand values. The model could then assist in the modeling of timber supply and in economic...

Gray Infrastructure Tool | EPA Center for Exposure ...

EPA Pesticide Factsheets

2016-03-07

Natural channel with flood plain panel added Default depth increment of 0.5 is used for Natural Channel with FP Units option added – SI or US units. Default option is US units Conversion options added wherever necessary Additional options added to FTABLE such as clear FTABLE Significant digits for FTABLE calculations is changed to 4 Previously a default Cd value is used for calculations (under-drain and riser) but now a user defined value is used Default values of Cd for riser orifice and under-drain textboxes is changed to 0.6 Previously a default increment value of 0.1 is used for all the channel panels but now user can specify the increment

75 FR 6772 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... series of IWM and SPY in increments of $0.01 effective February 1, 2010, contemporaneously with other... Exchange Act of 1934 (the ``Act'') \\1\\ and Rule 19b-4 thereunder,\\2\\ notice is hereby given that on January... solicit comments on the proposed rule change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR...

Development and use of the incremental twitch subtraction MUNE method in mice.

PubMed

Hegedus, Janka; Jones, Kelvin E; Gordon, Tessa

2009-01-01

We have used a technique to estimate the number of functioning motor units (MUNE) innervating a muscle in mice based on twitch tension. The MUNE technique was verified by modeling twitch tensions from isolated ventral root stimulation. Analysis by twitch tensions allowed us to identify motor unit fiber types. The MUNE technique was used to compare normal mice with transgenic superoxide dismutase-1 mutation (G94A) mice to assess the time course of motor unit loss with respect to fiber type. Motor unit loss was found to occur well in advance of behavioral changes and the degree of reinnervation is dependent upon motor unit fiber types.

Use of Attribute Driven Incremental Discretization and Logic Learning Machine to build a prognostic classifier for neuroblastoma patients.

PubMed

Cangelosi, Davide; Muselli, Marco; Parodi, Stefano; Blengio, Fabiola; Becherini, Pamela; Versteeg, Rogier; Conte, Massimo; Varesio, Luigi

2014-01-01

Cancer patient's outcome is written, in part, in the gene expression profile of the tumor. We previously identified a 62-probe sets signature (NB-hypo) to identify tissue hypoxia in neuroblastoma tumors and showed that NB-hypo stratified neuroblastoma patients in good and poor outcome 1. It was important to develop a prognostic classifier to cluster patients into risk groups benefiting of defined therapeutic approaches. Novel classification and data discretization approaches can be instrumental for the generation of accurate predictors and robust tools for clinical decision support. We explored the application to gene expression data of Rulex, a novel software suite including the Attribute Driven Incremental Discretization technique for transforming continuous variables into simplified discrete ones and the Logic Learning Machine model for intelligible rule generation. We applied Rulex components to the problem of predicting the outcome of neuroblastoma patients on the bases of 62 probe sets NB-hypo gene expression signature. The resulting classifier consisted in 9 rules utilizing mainly two conditions of the relative expression of 11 probe sets. These rules were very effective predictors, as shown in an independent validation set, demonstrating the validity of the LLM algorithm applied to microarray data and patients' classification. The LLM performed as efficiently as Prediction Analysis of Microarray and Support Vector Machine, and outperformed other learning algorithms such as C4.5. Rulex carried out a feature selection by selecting a new signature (NB-hypo-II) of 11 probe sets that turned out to be the most relevant in predicting outcome among the 62 of the NB-hypo signature. Rules are easily interpretable as they involve only few conditions. Our findings provided evidence that the application of Rulex to the expression values of NB-hypo signature created a set of accurate, high quality, consistent and interpretable rules for the prediction of neuroblastoma patients' outcome. We identified the Rulex weighted classification as a flexible tool that can support clinical decisions. For these reasons, we consider Rulex to be a useful tool for cancer classification from microarray gene expression data.

Timely confirmation of gastro-esophageal reflux disease via pH monitoring: estimating budget impact on managed care organizations.

PubMed

Lee, W C; Yeh, Y C; Lacy, B E; Pandolfino, J E; Brill, J V; Weinstein, M L; Carlson, A M; Williams, M J; Wittek, M R; Pashos, C L

2008-05-01

Current guidelines recommend the use of pH monitoring to confirm the diagnosis of acid reflux in patients with a normal endoscopy. This analysis evaluated the financial impact of pH monitoring with the wireless pH capsule on a managed care organization (MCO) in the United States. A decision model was constructed to project total 1-year costs to manage GERD symptoms with and without the adoption of wireless pH capsules in a hypothetical MCO with 10 000 eligible adult enrollees, of whom 600 presented with GERD-like symptoms. Costs of GERD diagnosis, treatment, and symptom management for those in whom a GERD diagnosis was ruled out by pH monitoring were assessed. The incremental per-member-per-month (PMPM) and per-treated-member-per-month (PTMPM) costs were the primary outcomes. Data sources included literature, expert input, and standardized fee schedules. An increase of 10 percentage points in the use of pH monitoring with wireless pH capsules yielded incremental PMPM and PTMPM costs of $0.029 and $0.481, respectively. The costs of proton pump inhibitor (PPI) therapy to the plan dropped to $236,363 from $238,086, while increases were observed in pH monitoring (from $16 739 to $21 973) and non-GERD therapy costs (from $1392 to $1740). The results were sensitive to the percentage of patients requiring repeat endoscopy before wireless pH monitoring and the cost of PPIs. Timely and increased use of pH monitoring as recommended in published guidelines leads to less unnecessary use of PPIs with a modest budgetary impact on health plans.

40 CFR Table 3 to Subpart Mmmm of... - Model Rule-Emission Limits and Standards for Existing Multiple Hearth Sewage Sludge Incineration...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Model Rule-Emission Limits and Standards for Existing Multiple Hearth Sewage Sludge Incineration Units 3 Table 3 to Subpart MMMM of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF...

40 CFR Table 3 to Subpart Mmmm of... - Model Rule-Emission Limits and Standards for Existing Multiple Hearth Sewage Sludge Incineration...

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Model Rule-Emission Limits and Standards for Existing Multiple Hearth Sewage Sludge Incineration Units 3 Table 3 to Subpart MMMM of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF...

40 CFR Table 7 to Subpart Bbbb of... - Model Rule-Requirements for Continuous Emission Monitoring Systems (CEMS)

Code of Federal Regulations, 2013 CFR

2013-07-01

... Emission Monitoring Systems (CEMS) 7 Table 7 to Subpart BBBB of Part 60 Protection of Environment... or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 7 Table 7 to Subpart BBBB of Part 60—Model Rule... sulfur dioxide emissions of the municipal waste combustion unit 4. Carbon Monoxide 125 percent of the...

40 CFR Table 7 to Subpart Bbbb of... - Model Rule-Requirements for Continuous Emission Monitoring Systems (CEMS)

Code of Federal Regulations, 2012 CFR

2012-07-01

... Emission Monitoring Systems (CEMS) 7 Table 7 to Subpart BBBB of Part 60 Protection of Environment... or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 7 Table 7 to Subpart BBBB of Part 60—Model Rule... sulfur dioxide emissions of the municipal waste combustion unit 4. Carbon Monoxide 125 percent of the...

40 CFR Table 7 to Subpart Bbbb of... - Model Rule-Requirements for Continuous Emission Monitoring Systems (CEMS)

Code of Federal Regulations, 2014 CFR

2014-07-01

... Emission Monitoring Systems (CEMS) 7 Table 7 to Subpart BBBB of Part 60 Protection of Environment... or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 7 Table 7 to Subpart BBBB of Part 60—Model Rule... sulfur dioxide emissions of the municipal waste combustion unit 4. Carbon Monoxide 125 percent of the...

40 CFR Table 4 to Subpart Bbbb of... - Model Rule-Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a

Code of Federal Regulations, 2011 CFR

2011-07-01

... Existing Small Municipal Waste Combustion Unit a 4 Table 4 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a For...

40 CFR Table 2 to Subpart Bbbb of... - Model Rule-Class I Emission Limits for Existing Small Municipal Waste Combustion Units a

Code of Federal Regulations, 2014 CFR

2014-07-01

... Existing Small Municipal Waste Combustion Units a 2 Table 2 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class I Emission Limits for Existing Small Municipal Waste Combustion Units a For...

40 CFR Table 4 to Subpart Bbbb of... - Model Rule-Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a

Code of Federal Regulations, 2014 CFR

2014-07-01

... Existing Small Municipal Waste Combustion Unit a 4 Table 4 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a For...

40 CFR Table 4 to Subpart Bbbb of... - Model Rule-Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a

Code of Federal Regulations, 2010 CFR

2010-07-01

... Existing Small Municipal Waste Combustion Unit a 4 Table 4 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a For...

40 CFR Table 2 to Subpart Bbbb of... - Model Rule-Class I Emission Limits for Existing Small Municipal Waste Combustion Units a

Code of Federal Regulations, 2012 CFR

2012-07-01

... Existing Small Municipal Waste Combustion Units a 2 Table 2 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class I Emission Limits for Existing Small Municipal Waste Combustion Units a For...

40 CFR Table 2 to Subpart Bbbb of... - Model Rule-Class I Emission Limits for Existing Small Municipal Waste Combustion Units a

Code of Federal Regulations, 2013 CFR

2013-07-01

... Existing Small Municipal Waste Combustion Units a 2 Table 2 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class I Emission Limits for Existing Small Municipal Waste Combustion Units a For...

40 CFR Table 2 to Subpart Bbbb of... - Model Rule-Class I Emission Limits for Existing Small Municipal Waste Combustion Units a

Code of Federal Regulations, 2010 CFR

2010-07-01

... Existing Small Municipal Waste Combustion Units a 2 Table 2 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class I Emission Limits for Existing Small Municipal Waste Combustion Units a For...

40 CFR Table 2 to Subpart Bbbb of... - Model Rule-Class I Emission Limits for Existing Small Municipal Waste Combustion Units a

Code of Federal Regulations, 2011 CFR

2011-07-01

... Existing Small Municipal Waste Combustion Units a 2 Table 2 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class I Emission Limits for Existing Small Municipal Waste Combustion Units a For...

40 CFR Table 4 to Subpart Bbbb of... - Model Rule-Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a

Code of Federal Regulations, 2012 CFR

2012-07-01

... Existing Small Municipal Waste Combustion Unit a 4 Table 4 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a For...

40 CFR Table 4 to Subpart Bbbb of... - Model Rule-Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a

Code of Federal Regulations, 2013 CFR

2013-07-01

... Existing Small Municipal Waste Combustion Unit a 4 Table 4 to Subpart BBBB of Part 60 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion... Part 60—Model Rule—Class II Emission Limits for Existing Small Municipal Waste Combustion Unit a For...

Wigner Distribution Function: Relation to Short-Term Spectral Estimation, Smoothing, and Performance in Noise.

DTIC Science & Technology

1988-02-16

integration rule . In particular, if we use the Trapezoidal rule and carry out the summnation over -oo, -aO, we have approximation S~~f 2A 2 exp(-14mfka...increment a and using the Trapezoidal rule : 66 ~inr J~M ’~j i ’.m -1p w A .X i 7NX~ .m-m- -_-_ I% -.M’’I j %W I W - IR 8225 -1/4 Su(t,f) (, 2) -1-i2ft...lhe STSE is given by (102) and (103). A discrete approximation, by means of the Trapezoidal rule , is furnished by t(t,f) a u exp(-i27fAk) s(kA) *(t

Genetic attack on neural cryptography.

PubMed

Ruttor, Andreas; Kinzel, Wolfgang; Naeh, Rivka; Kanter, Ido

2006-03-01

Different scaling properties for the complexity of bidirectional synchronization and unidirectional learning are essential for the security of neural cryptography. Incrementing the synaptic depth of the networks increases the synchronization time only polynomially, but the success of the geometric attack is reduced exponentially and it clearly fails in the limit of infinite synaptic depth. This method is improved by adding a genetic algorithm, which selects the fittest neural networks. The probability of a successful genetic attack is calculated for different model parameters using numerical simulations. The results show that scaling laws observed in the case of other attacks hold for the improved algorithm, too. The number of networks needed for an effective attack grows exponentially with increasing synaptic depth. In addition, finite-size effects caused by Hebbian and anti-Hebbian learning are analyzed. These learning rules converge to the random walk rule if the synaptic depth is small compared to the square root of the system size.

Constitutive law for the densification of fused silica with applications in polishing and microgrinding

NASA Astrophysics Data System (ADS)

Lambropoulos, John C.; Fang, Tong; Xu, Su; Gracewski, Sheryl M.

1995-09-01

We discuss a constitutive model describing the permanent densification of fused silica under large applied pressures and shear stresses. The constitutive law is assumed to be rate- independent, and uses a yield function coupling hydrostatic pressure and shear stress, a flow rule describing the evolution of permanent strains after initial densification, and a hardening rule describing the dependence of the incremental densification on the levels of applied stresses. The constitutive law accounts for multiaxial states of stress, since during polishing and grinding operations complex stress states occur in a thin surface layer due to the action of abrasive particles. Due to frictional and other abrasive forces, large shear stresses are present near the surface during manufacturing. We apply the constitutive law in estimating the extent of the densified layer during the mechanical interaction of an abrasive grain and a flat surface.

Genetic attack on neural cryptography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruttor, Andreas; Kinzel, Wolfgang; Naeh, Rivka

2006-03-15

Different scaling properties for the complexity of bidirectional synchronization and unidirectional learning are essential for the security of neural cryptography. Incrementing the synaptic depth of the networks increases the synchronization time only polynomially, but the success of the geometric attack is reduced exponentially and it clearly fails in the limit of infinite synaptic depth. This method is improved by adding a genetic algorithm, which selects the fittest neural networks. The probability of a successful genetic attack is calculated for different model parameters using numerical simulations. The results show that scaling laws observed in the case of other attacks hold formore » the improved algorithm, too. The number of networks needed for an effective attack grows exponentially with increasing synaptic depth. In addition, finite-size effects caused by Hebbian and anti-Hebbian learning are analyzed. These learning rules converge to the random walk rule if the synaptic depth is small compared to the square root of the system size.« less

Genetic attack on neural cryptography

NASA Astrophysics Data System (ADS)

Ruttor, Andreas; Kinzel, Wolfgang; Naeh, Rivka; Kanter, Ido

2006-03-01

Different scaling properties for the complexity of bidirectional synchronization and unidirectional learning are essential for the security of neural cryptography. Incrementing the synaptic depth of the networks increases the synchronization time only polynomially, but the success of the geometric attack is reduced exponentially and it clearly fails in the limit of infinite synaptic depth. This method is improved by adding a genetic algorithm, which selects the fittest neural networks. The probability of a successful genetic attack is calculated for different model parameters using numerical simulations. The results show that scaling laws observed in the case of other attacks hold for the improved algorithm, too. The number of networks needed for an effective attack grows exponentially with increasing synaptic depth. In addition, finite-size effects caused by Hebbian and anti-Hebbian learning are analyzed. These learning rules converge to the random walk rule if the synaptic depth is small compared to the square root of the system size.

Undermining the rules in home care services for the elderly in Norway: flexibility and cooperation.

PubMed

Wollscheid, Sabine; Eriksen, John; Hallvik, Jørgen

2013-06-01

This study explores the provision of home care services (home nursing and domiciliary help) for the elderly in Norwegian municipalities with purchaser-provider split model. The study draws on the assumption that flexibility in adjusting services to the care receivers' needs, and cooperation between provider and purchasers are indicators of good quality of care. Data were collected through semi-structured telephone interviews with 22 team leaders of provider units in nine municipalities. Data were collected in 2008-2009. The study has been approved by the Norwegian Social Science Data Services. We identified four different ways of organising home care services under a purchaser-provider split model: Provider empowerment, New Public Management, Vague instructions and undermining the rules. High flexibility in providing care and cooperation with the purchaser unit were identified by the team leaders as characteristics for good care. Our findings suggest that the care providers use individual strategies that allow flexibility and cooperation rather than rigidly abiding to the regulations the purchaser-provider split models implies. Ironically, in provider units where the 'rules were undermined', the informants (team leaders of provider units) seemed to be most satisfied with the quality of home care that they delivered. © 2012 Nordic College of Caring Science.

The composite load spectra project

NASA Technical Reports Server (NTRS)

Newell, J. F.; Ho, H.; Kurth, R. E.

1990-01-01

Probabilistic methods and generic load models capable of simulating the load spectra that are induced in space propulsion system components are being developed. Four engine component types (the transfer ducts, the turbine blades, the liquid oxygen posts and the turbopump oxidizer discharge duct) were selected as representative hardware examples. The composite load spectra that simulate the probabilistic loads for these components are typically used as the input loads for a probabilistic structural analysis. The knowledge-based system approach used for the composite load spectra project provides an ideal environment for incremental development. The intelligent database paradigm employed in developing the expert system provides a smooth coupling between the numerical processing and the symbolic (information) processing. Large volumes of engine load information and engineering data are stored in database format and managed by a database management system. Numerical procedures for probabilistic load simulation and database management functions are controlled by rule modules. Rules were hard-wired as decision trees into rule modules to perform process control tasks. There are modules to retrieve load information and models. There are modules to select loads and models to carry out quick load calculations or make an input file for full duty-cycle time dependent load simulation. The composite load spectra load expert system implemented today is capable of performing intelligent rocket engine load spectra simulation. Further development of the expert system will provide tutorial capability for users to learn from it.

Incremental Costs and Cost Effectiveness of Intensive Treatment in Individuals with Type 2 Diabetes Detected by Screening in the ADDITION-UK Trial: An Update with Empirical Trial-Based Cost Data.

PubMed

Laxy, Michael; Wilson, Edward C F; Boothby, Clare E; Griffin, Simon J

2017-12-01

There is uncertainty about the cost effectiveness of early intensive treatment versus routine care in individuals with type 2 diabetes detected by screening. To derive a trial-informed estimate of the incremental costs of intensive treatment as delivered in the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care-Europe (ADDITION) trial and to revisit the long-term cost-effectiveness analysis from the perspective of the UK National Health Service. We analyzed the electronic primary care records of a subsample of the ADDITION-Cambridge trial cohort (n = 173). Unit costs of used primary care services were taken from the published literature. Incremental annual costs of intensive treatment versus routine care in years 1 to 5 after diagnosis were calculated using multilevel generalized linear models. We revisited the long-term cost-utility analyses for the ADDITION-UK trial cohort and reported results for ADDITION-Cambridge using the UK Prospective Diabetes Study Outcomes Model and the trial-informed cost estimates according to a previously developed evaluation framework. Incremental annual costs of intensive treatment over years 1 to 5 averaged £29.10 (standard error = £33.00) for consultations with general practitioners and nurses and £54.60 (standard error = £28.50) for metabolic and cardioprotective medication. For ADDITION-UK, over the 10-, 20-, and 30-year time horizon, adjusted incremental quality-adjusted life-years (QALYs) were 0.014, 0.043, and 0.048, and adjusted incremental costs were £1,021, £1,217, and £1,311, resulting in incremental cost-effectiveness ratios of £71,232/QALY, £28,444/QALY, and £27,549/QALY, respectively. Respective incremental cost-effectiveness ratios for ADDITION-Cambridge were slightly higher. The incremental costs of intensive treatment as delivered in the ADDITION-Cambridge trial were lower than expected. Given UK willingness-to-pay thresholds in patients with screen-detected diabetes, intensive treatment is of borderline cost effectiveness over a time horizon of 20 years and more. Copyright © 2017. Published by Elsevier Inc.

Effect of conventional and square stores on the longitudinal aerodynamic characteristics of a fighter aircraft model at supersonic speeds. [in the langley unitary plan wind tunnel

NASA Technical Reports Server (NTRS)

Monta, W. J.

1980-01-01

The effects of conventional and square stores on the longitudinal aerodynamic characteristics of a fighter aircraft configuration at Mach numbers of 1.6, 1.8, and 2.0 was investigated. Five conventional store configurations and six arrangements of a square store configuration were studied. All configurations of the stores produced small, positive increments in the pitching moment throughout the angle-of-attack range, but the configuration with area ruled wing tanks also had a slight decrease on stability at the higher angles of attack. There were some small changes in lift coefficient because of the addition of the stores, causing the drag increment to vary with the lift coefficient. As a result, there were corresponding changes in the increments of the maximum lift drag ratios. The store drag coefficient based on the cross sectional area of the stores ranged from a maximum of 1.1 for the configuration with three Maverick missiles to a minimum of about .040 for the two MK-84 bombs and the arrangements with four square stores touching or two square stores in tandem. Square stores located side by side yielded about 0.50 in the aft position compared to 0.74 in the forward position.

40 CFR Table 7 to Subpart Dddd of... - Model Rule-Emission Limitations That Apply to Energy Recovery Units After May 20, 2011

Code of Federal Regulations, 2014 CFR

2014-07-01

... Apply to Energy Recovery Units After May 20, 2011 7 Table 7 to Subpart DDDD of Part 60 Protection of... Waste Incineration Units Pt. 60, Subpt. DDDD, Table 7 Table 7 to Subpart DDDD of Part 60—Model Rule—Emission Limitations That Apply to Energy Recovery Units After May 20, 2011 [Date to be specified in state...

40 CFR Table 7 to Subpart Dddd of... - Model Rule-Emission Limitations That Apply to Energy Recovery Units After May 20, 2011

Code of Federal Regulations, 2013 CFR

2013-07-01

... Apply to Energy Recovery Units After May 20, 2011 7 Table 7 to Subpart DDDD of Part 60 Protection of... Waste Incineration Units Pt. 60, Subpt. DDDD, Table 7 Table 7 to Subpart DDDD of Part 60—Model Rule—Emission Limitations That Apply to Energy Recovery Units After May 20, 2011 [Date to be specified in state...

Unit Hydrograph Peaking Analysis for Goose Creek Watershed in Virginia: A Case Study

DTIC Science & Technology

2017-05-01

increment would not exceed 1.5 times the designed unit peak. The purpose of this study is to analyze the validity of this UHPF range of the Goose...confidence interval precipitation depths to the watershed in addition to the 50% value. This study concluded that a design event with a return period greater...In this study , the physically based GSSHA model was deployed to obtain corresponding design discharge from probable rainfall events. 3.2.1 GSSHA

Incremental social learning in particle swarms.

PubMed

de Oca, Marco A Montes; Stutzle, Thomas; Van den Enden, Ken; Dorigo, Marco

2011-04-01

Incremental social learning (ISL) was proposed as a way to improve the scalability of systems composed of multiple learning agents. In this paper, we show that ISL can be very useful to improve the performance of population-based optimization algorithms. Our study focuses on two particle swarm optimization (PSO) algorithms: a) the incremental particle swarm optimizer (IPSO), which is a PSO algorithm with a growing population size in which the initial position of new particles is biased toward the best-so-far solution, and b) the incremental particle swarm optimizer with local search (IPSOLS), in which solutions are further improved through a local search procedure. We first derive analytically the probability density function induced by the proposed initialization rule applied to new particles. Then, we compare the performance of IPSO and IPSOLS on a set of benchmark functions with that of other PSO algorithms (with and without local search) and a random restart local search algorithm. Finally, we measure the benefits of using incremental social learning on PSO algorithms by running IPSO and IPSOLS on problems with different fitness distance correlations.

SUSTAIN: a network model of category learning.

PubMed

Love, Bradley C; Medin, Douglas L; Gureckis, Todd M

2004-04-01

SUSTAIN (Supervised and Unsupervised STratified Adaptive Incremental Network) is a model of how humans learn categories from examples. SUSTAIN initially assumes a simple category structure. If simple solutions prove inadequate and SUSTAIN is confronted with a surprising event (e.g., it is told that a bat is a mammal instead of a bird), SUSTAIN recruits an additional cluster to represent the surprising event. Newly recruited clusters are available to explain future events and can themselves evolve into prototypes-attractors-rules. SUSTAIN's discovery of category substructure is affected not only by the structure of the world but by the nature of the learning task and the learner's goals. SUSTAIN successfully extends category learning models to studies of inference learning, unsupervised learning, category construction, and contexts in which identification learning is faster than classification learning.

A cost effective model for appropriate administration of red cell units and salvaging un-transfused red cell units by using temperature sensitive indicators for blood component transportation in a hospital setting.

PubMed

Tiwari, Aseem K; Sharma, Pooja; Pandey, Prashant K; Rawat, Ganesh S; Dixit, Surbhi; Raina, Vimarsh; Bhargava, Richa

2015-01-01

A rule called "30-min rule" defines that red cell unit cannot be used if it has been out of blood bank refrigerator for over 30 min. This rule is useful to guide initiation of transfusion, but is inadequate for deciding whether to reuse or discard units received-back at blood transfusion services (BTS). A simple cost-effective temperature-sensitive indicator was evaluated to decide upon reuse (cold chain was uninterrupted) or discard (where cold chain was interrupted) in a simulation exercise. Temperature-sensitive indicators TH-F™ that irreversibly changed color from white to red demonstrated that heat excursion has occurred and the cumulative temperature has exceeded 10°C for over 30 min, were used in outdated red cells for simulating units, which are not used and received-back. These units were also tagged with a standard temperature monitoring device, which was a re-usable credit card sized device, which would log the actual time and temperature. In few units percent hemolysis was also calculated. Statistically insignificant elevation in average temperature was noted in 102 simulated units at the time of return to BTS (Δ 0.04°C), despite the fact that these units were in the transport box for over 4 h. The average supernatant hemoglobin in these units was 0.24%, much below the prescribed threshold. Transportation of blood in controlled conditions with temperature-sensitive indicator is a cost-effective model to save blood, a precious human resource.

40 CFR 60.2610 - What must I do if I close my CISWI unit and then restart it?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule...

40 CFR 60.2610 - What must I do if I close my CISWI unit and then restart it?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule...

40 CFR Table 1 to Subpart Ffff of... - Model Rule-Compliance Schedule

Code of Federal Regulations, 2010 CFR

2010-07-01

... Compliance Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9... devices so that, when the incineration unit is brought on line, all process changes and air pollution...

40 CFR Table 1 to Subpart Ffff of... - Model Rule-Compliance Schedule

Code of Federal Regulations, 2011 CFR

2011-07-01

... Compliance Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9... devices so that, when the incineration unit is brought on line, all process changes and air pollution...

40 CFR Table 1 to Subpart Uuu of... - Metal HAP Emission Limits for Catalytic Cracking Units

Code of Federal Regulations, 2010 CFR

2010-07-01

... heat boiler in which you burn auxiliary or in supplemental liquid or solid fossil fuel, the incremental... thermal units (lb/million Btu) of heat input attributable to the liquid or solid fossil fuel; and the... supplemental liquid or solid fossil fuel, the incremental rate of PM must not exceed 43.0 g/GJ (0.10 lb/million...

40 CFR Table 1 to Subpart Uuu of... - Metal HAP Emission Limits for Catalytic Cracking Units

Code of Federal Regulations, 2011 CFR

2011-07-01

... heat boiler in which you burn auxiliary or in supplemental liquid or solid fossil fuel, the incremental... thermal units (lb/million Btu) of heat input attributable to the liquid or solid fossil fuel; and the... supplemental liquid or solid fossil fuel, the incremental rate of PM must not exceed 43.0 g/GJ (0.10 lb/million...

40 CFR 62.14540 - When must I complete each increment of progress?

Code of Federal Regulations, 2011 CFR

2011-07-01

... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That Commenced Construction On or Before November 30, 1999 Compliance Schedule and Increments of Progress § 62...

40 CFR 62.14540 - When must I complete each increment of progress?

Code of Federal Regulations, 2013 CFR

2013-07-01

... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That Commenced Construction On or Before November 30, 1999 Compliance Schedule and Increments of Progress § 62...

Effect of Aspiration and Mean Gain on the Emergence of Cooperation in Unidirectional Pedestrian Flow

NASA Astrophysics Data System (ADS)

Wang, Zi-Yang; Ma, Jian; Zhao, Hui; Qin, Yong; Zhu, Wei; Jia, Li-Min

2013-03-01

When more than one pedestrian want to move to the same site, conflicts appear and thus the involved pedestrians play a motion game. In order to describe the emergence of cooperation during the conflict resolving process, an evolutionary cellular automation model is established considering the effect of aspiration and mean gain. In each game, pedestrian may be gentle cooperator or aggressive defector. We propose a set of win-stay-lose-shrift (WSLS) like rules for updating pedestrian's strategy. These rules prescribe that if the mean gain of current strategy between some given steps is larger than aspiration the strategy keeps, otherwise the strategy changes. The simulation results show that a high level aspiration will lead to more cooperation. With the increment of the statistic length, pedestrians will be more rational in decision making. It is also found that when the aspiration level is small enough and the statistic length is large enough all the pedestrian will turn to defectors. We use the prisoner's dilemma model to explain it. At last we discuss the effect of aspiration on fundamental diagram.

Emotional display rules as work unit norms: a multilevel analysis of emotional labor among nurses.

PubMed

Diefendorff, James M; Erickson, Rebecca J; Grandey, Alicia A; Dahling, Jason J

2011-04-01

Emotional labor theory has conceptualized emotional display rules as shared norms governing the expression of emotions at work. Using a sample of registered nurses working in different units of a hospital system, we provided the first empirical evidence that display rules can be represented as shared, unit-level beliefs. Additionally, controlling for the influence of dispositional affectivity, individual-level display rule perceptions, and emotion regulation, we found that unit-level display rules are associated with individual-level job satisfaction. We also showed that unit-level display rules relate to burnout indirectly through individual-level display rule perceptions and emotion regulation strategies. Finally, unit-level display rules also interacted with individual-level dispositional affectivity to predict employee use of emotion regulation strategies. We discuss how future research on emotional labor and display rules, particularly in the health care setting, can build on these findings.

40 CFR Table 4 to Subpart Mmmm of... - Model Rule-Operating Parameters for Existing Sewage Sludge Incineration Units a

Code of Federal Regulations, 2013 CFR

2013-07-01

... Existing Sewage Sludge Incineration Units a 4 Table 4 to Subpart MMMM of Part 60 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Pt. 60... Sewage Sludge Incineration Units a For these operating parameters You must establish these operating...

40 CFR Table 4 to Subpart Mmmm of... - Model Rule-Operating Parameters for Existing Sewage Sludge Incineration Units a

Code of Federal Regulations, 2014 CFR

2014-07-01

... Existing Sewage Sludge Incineration Units a 4 Table 4 to Subpart MMMM of Part 60 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Existing Sewage Sludge Incineration Units Pt. 60... Sewage Sludge Incineration Units a For these operating parameters You must establish these operating...

Common Aviation Command and Control System Increment 1 (CAC2S Inc 1)

DTIC Science & Technology

2016-03-01

Command and Control System Increment 1 ( CAC2S Inc 1) DoD Component Navy United States Marine Corps Responsible Office Program Manager References MAIS ...facilities for planning and execution of Marine Aviation missions within the Marine Air Ground Task Force (MAGTF). CAC2S Increment I will eliminate...approved by ASN (RDA), the MDA, in a Program Decision Memorandum (PDM), “ CAC2S Increment I,” May 05, 2009. As the result of the PDM, the independent

40 CFR 62.14555 - What if I do not meet an increment of progress?

Code of Federal Regulations, 2013 CFR

2013-07-01

... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That Commenced Construction On or Before November 30, 1999 Compliance Schedule and Increments of Progress § 62...

40 CFR 62.14555 - What if I do not meet an increment of progress?

Code of Federal Regulations, 2011 CFR

2011-07-01

... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That Commenced Construction On or Before November 30, 1999 Compliance Schedule and Increments of Progress § 62...

Process Simulation of Cold Pressing and Sintering of Armstrong CP-Ti Powders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gorti, Sarma B; Sabau, Adrian S; Peter, William H

A computational methodology is presented for the process simulation of cold pressing and sintering of Armstrong CP-Ti powders. Since the powder consolidation is governed by specific pressure-dependent constitutive equations, solution algorithms were developed for the ABAQUS user material subroutine, UMAT, for computing the plastic strain increments based on an implicit integration of the nonlinear yield function, flow rule, and hardening equations. Sintering was simulated using a model based on diffusional creep using the user subroutine CREEP. The initial mesh, stress, and density for the simulation of sintering were obtained from the results of the cold pressing simulation, minimizing the errorsmore » from decoupling the cold pressing and sintering simulations. Numerical simulation results are presented for the cold compaction followed by a sintering step of the Ti powders. The numerical simulation results for the relative density were compared to those measured from experiments before and after sintering, showing that the relative density can be accurately predicted. Notice: This manuscript has been authored by UT-Battelle, LLC, under Contract No. DE-AC05-00OR22725 with the U.S. Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes. ACKNOWLEDGEMENTS This research was sponsored by the U.S. DOE, and carried out at ORNL, under Contract DE-AC05-00OR22725 with UT-Battelle, LLC. This research was sponsored by the U.S. DOE, EERE Industrial Technology Program Office under CPS Agreement # 17881.« less

Linear dichroism of DNA: Characterization of the orientation distribution function caused by hydrodynamic shear

DOE PAGES

Sutherland, John C.

2017-04-15

Linear dichroism provides information on the orientation of chromophores part of, or bound to, an orientable molecule such as DNA. For molecular alignment induced by hydrodynamic shear, the principal axes orthogonal to the direction of alignment are not equivalent. Thus, the magnitude of the flow-induced change in absorption for light polarized parallel to the direction of flow can be more than a factor of two greater than the corresponding change for light polarized perpendicular to both that direction and the shear axis. The ratio of the two flow-induced changes in absorption, the dichroic increment ratio, is characterized using the orthogonalmore » orientation model, which assumes that each absorbing unit is aligned parallel to one of the principal axes of the apparatus. The absorption of the alienable molecules is characterized by components parallel and perpendicular to the orientable axis of the molecule. The dichroic increment ratio indicates that for the alignment of DNA in rectangular flow cells, average alignment is not uniaxial, but for higher shear, as produced in a Couette cell, it can be. The results from the simple model are identical to tensor models for typical experimental configuration. Approaches for measuring the dichroic increment ratio with modern dichrometers are further discussed.« less

Linear dichroism of DNA: Characterization of the orientation distribution function caused by hydrodynamic shear

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sutherland, John C.

Linear dichroism provides information on the orientation of chromophores part of, or bound to, an orientable molecule such as DNA. For molecular alignment induced by hydrodynamic shear, the principal axes orthogonal to the direction of alignment are not equivalent. Thus, the magnitude of the flow-induced change in absorption for light polarized parallel to the direction of flow can be more than a factor of two greater than the corresponding change for light polarized perpendicular to both that direction and the shear axis. The ratio of the two flow-induced changes in absorption, the dichroic increment ratio, is characterized using the orthogonalmore » orientation model, which assumes that each absorbing unit is aligned parallel to one of the principal axes of the apparatus. The absorption of the alienable molecules is characterized by components parallel and perpendicular to the orientable axis of the molecule. The dichroic increment ratio indicates that for the alignment of DNA in rectangular flow cells, average alignment is not uniaxial, but for higher shear, as produced in a Couette cell, it can be. The results from the simple model are identical to tensor models for typical experimental configuration. Approaches for measuring the dichroic increment ratio with modern dichrometers are further discussed.« less

Linear dichroism of DNA: Characterization of the orientation distribution function caused by hydrodynamic shear.

PubMed

Sutherland, John C

2017-04-15

Linear dichroism provides information on the orientation of chromophores part of, or bound to, an orientable molecule such as DNA. For molecular alignment induced by hydrodynamic shear, the principal axes orthogonal to the direction of alignment are not equivalent. Thus, the magnitude of the flow-induced change in absorption for light polarized parallel to the direction of flow can be more than a factor of two greater than the corresponding change for light polarized perpendicular to both that direction and the shear axis. The ratio of the two flow-induced changes in absorption, the dichroic increment ratio, is characterized using the orthogonal orientation model, which assumes that each absorbing unit is aligned parallel to one of the principal axes of the apparatus. The absorption of the alienable molecules is characterized by components parallel and perpendicular to the orientable axis of the molecule. The dichroic increment ratio indicates that for the alignment of DNA in rectangular flow cells, average alignment is not uniaxial, but for higher shear, as produced in a Couette cell, it can be. The results from the simple model are identical to tensor models for typical experimental configurations. Approaches for measuring the dichroic increment ratio with modern dichrometers are discussed. Copyright © 2017. Published by Elsevier Inc.

40 CFR Table 5 to Subpart Bbbb of... - Model Rule-Carbon Monoxide Emission Limits for Existing Small Municipal Waste Combustion Units

Code of Federal Regulations, 2012 CFR

2012-07-01

... Limits for Existing Small Municipal Waste Combustion Units 5 Table 5 to Subpart BBBB of Part 60... Combustion Units Constructed on or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 5 Table 5 to Subpart... Combustion Units For the following municipal waste combustion units You must meet the following carbon...

40 CFR Table 5 to Subpart Bbbb of... - Model Rule-Carbon Monoxide Emission Limits for Existing Small Municipal Waste Combustion Units

Code of Federal Regulations, 2014 CFR

2014-07-01

... Limits for Existing Small Municipal Waste Combustion Units 5 Table 5 to Subpart BBBB of Part 60... Combustion Units Constructed on or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 5 Table 5 to Subpart... Combustion Units For the following municipal waste combustion units You must meet the following carbon...

40 CFR Table 5 to Subpart Bbbb of... - Model Rule-Carbon Monoxide Emission Limits for Existing Small Municipal Waste Combustion Units

Code of Federal Regulations, 2010 CFR

2010-07-01

... Limits for Existing Small Municipal Waste Combustion Units 5 Table 5 to Subpart BBBB of Part 60... Combustion Units Constructed on or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 5 Table 5 to Subpart... Combustion Units For the following municipal waste combustion units You must meet the following carbon...

40 CFR Table 5 to Subpart Bbbb of... - Model Rule-Carbon Monoxide Emission Limits for Existing Small Municipal Waste Combustion Units

Code of Federal Regulations, 2013 CFR

2013-07-01

... Limits for Existing Small Municipal Waste Combustion Units 5 Table 5 to Subpart BBBB of Part 60... Combustion Units Constructed on or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 5 Table 5 to Subpart... Combustion Units For the following municipal waste combustion units You must meet the following carbon...

40 CFR Table 5 to Subpart Bbbb of... - Model Rule-Carbon Monoxide Emission Limits for Existing Small Municipal Waste Combustion Units

Code of Federal Regulations, 2011 CFR

2011-07-01

... Limits for Existing Small Municipal Waste Combustion Units 5 Table 5 to Subpart BBBB of Part 60... Combustion Units Constructed on or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 5 Table 5 to Subpart... Combustion Units For the following municipal waste combustion units You must meet the following carbon...

Access criteria for anti-TNF agents in spondyloarthritis: influence on comparative 1-year cost-effectiveness estimates.

PubMed

Harvard, Stephanie; Guh, Daphne; Bansback, Nick; Richette, Pascal; Saraux, Alain; Fautrel, Bruno; Anis, Aslam

2017-01-01

Anti-tumor necrosis factor (anti-TNF) agents are an effective, but costly, treatment for spondyloarthritis (SpA). Worldwide, multiple sets of access criteria aim to restrict anti-TNF therapy to patients with specific clinical characteristics, yet the influence of access criteria on anti-TNF cost-effectiveness is unknown. Our objective was to use data from the DESIR cohort, a prospective study of early SpA patients in France, to determine whether the French anti-TNF access criteria are the most cost-effective in that setting relative to other potential restrictions. We used data from the DESIR cohort to create five study populations of patients meeting anti-TNF access criteria from Canada, France, Germany, United Kingdom, and Hong Kong, respectively. For each study population, we calculated the costs and quality-adjusted life years (QALYs) over 1 year of patients treated and not treated with anti-TNF therapy. To control for differences between anti-TNF users and non-users, we used linear regression models to derive adjusted mean costs and QALYs. We calculated incremental cost-effectiveness ratios (ICERs) representing the incremental cost per additional QALY gained by treating with an anti-TNF within each of the five study populations, using bootstrapping to explore the range of uncertainty in costs and QALYs. A series of sensitivity analyses was conducted, including one to simulate the effect of a 24-week stopping rule for anti-TNF non-responders. Anti-TNF access criteria from France were satisfied by the largest proportion of DESIR patients (27.8%), followed by Germany (25.1%), Canada (23.8%), the UK (12.1%) and Hong Kong (8.6%). Confidence intervals around incremental costs and QALYs in the basecase analysis were overlapping, indicating that anti-TNF cost-effectiveness estimates derived from each subset were similar. In the sensitivity analysis that examined the effect of excluding costs accumulated past 24 weeks by anti-TNF non-responders, the incremental cost per QALY was reduced by approximately 25% relative to the basecase analysis (France: €857,992 vs. €1,105,859; Canada: € 626,459 vs. €818,186; Germany: € 422,568 vs. €545,808); UK €578,899 vs. €766,217; Hong Kong €335,418 vs. €456,850). Anti-TNF cost-effectiveness is strongly affected by treatment continuation among non-responders. Access criteria could improve anti-TNF cost-effectiveness by defining patients likely to respond.

77 FR 68087 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-15

... Source Review (NSR) permit programs); provisions for air pollution modeling; and provisions for public... the eastern United States (i.e., the Transport Rule, also known as the Cross-State Air Pollution Rule... and applicable federal air pollution control regulations and other permanent and enforceable...

40 CFR 60.1690 - What are the operating practice requirements for my municipal waste combustion unit?

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirements for my municipal waste combustion unit? 60.1690 Section 60.1690 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operating Requirements § 60.1690 What...

40 CFR 60.1690 - What are the operating practice requirements for my municipal waste combustion unit?

Code of Federal Regulations, 2014 CFR

2014-07-01

... requirements for my municipal waste combustion unit? 60.1690 Section 60.1690 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operating Requirements § 60.1690 What...

40 CFR 60.1690 - What are the operating practice requirements for my municipal waste combustion unit?

Code of Federal Regulations, 2013 CFR

2013-07-01

... requirements for my municipal waste combustion unit? 60.1690 Section 60.1690 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operating Requirements § 60.1690 What...

40 CFR 60.1690 - What are the operating practice requirements for my municipal waste combustion unit?

Code of Federal Regulations, 2011 CFR

2011-07-01

... requirements for my municipal waste combustion unit? 60.1690 Section 60.1690 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operating Requirements § 60.1690 What...

40 CFR 60.1690 - What are the operating practice requirements for my municipal waste combustion unit?

Code of Federal Regulations, 2012 CFR

2012-07-01

... requirements for my municipal waste combustion unit? 60.1690 Section 60.1690 Protection of Environment... SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operating Requirements § 60.1690 What...

75 FR 53613 - Notice of Data Availability Supporting Federal Implementation Plans To Reduce Interstate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-01

... files should avoid the use of special characters, avoid any form of encryption, and be free of any... modeling. This includes both units affected by the Proposed Transport Rule and other EGUs (e.g. fossil-fired units smaller than 25 MWe, non-fossil-fired units, and fossil-fired units 25 MWe or greater in...

Shale gas development: a smart regulation framework.

PubMed

Konschnik, Katherine E; Boling, Mark K

2014-01-01

Advances in directional drilling and hydraulic fracturing have sparked a natural gas boom from shale formations in the United States. Regulators face a rapidly changing industry comprised of hundreds of players, operating tens of thousands of wells across 30 states. They are often challenged to respond by budget cuts, a brain drain to industry, regulations designed for conventional gas developments, insufficient information, and deeply polarized debates about hydraulic fracturing and its regulation. As a result, shale gas governance remains a halting patchwork of rules, undermining opportunities to effectively characterize and mitigate development risk. The situation is dynamic, with research and incremental regulatory advances underway. Into this mix, we offer the CO/RE framework--characterization of risk, optimization of mitigation strategies, regulation, and enforcement--to design tailored governance strategies. We then apply CO/RE to three types of shale gas risks, to illustrate its potential utility to regulators.

Rule extraction from minimal neural networks for credit card screening.

PubMed

Setiono, Rudy; Baesens, Bart; Mues, Christophe

2011-08-01

While feedforward neural networks have been widely accepted as effective tools for solving classification problems, the issue of finding the best network architecture remains unresolved, particularly so in real-world problem settings. We address this issue in the context of credit card screening, where it is important to not only find a neural network with good predictive performance but also one that facilitates a clear explanation of how it produces its predictions. We show that minimal neural networks with as few as one hidden unit provide good predictive accuracy, while having the added advantage of making it easier to generate concise and comprehensible classification rules for the user. To further reduce model size, a novel approach is suggested in which network connections from the input units to this hidden unit are removed by a very straightaway pruning procedure. In terms of predictive accuracy, both the minimized neural networks and the rule sets generated from them are shown to compare favorably with other neural network based classifiers. The rules generated from the minimized neural networks are concise and thus easier to validate in a real-life setting.

Optimizing Early Rule-Out Strategies for Acute Myocardial Infarction: Utility of 1-Hour Copeptin.

PubMed

Hillinger, Petra; Twerenbold, Raphael; Jaeger, Cedric; Wildi, Karin; Reichlin, Tobias; Rubini Gimenez, Maria; Engels, Ulrike; Miró, Oscar; Boeddinghaus, Jasper; Puelacher, Christian; Nestelberger, Thomas; Röthlisberger, Michèle; Ernst, Susanne; Rentsch, Katharina; Mueller, Christian

2015-12-01

Combined testing of high-sensitivity cardiac troponin T (hs-cTnT) and copeptin at presentation provides a very high-although still imperfect-negative predictive value (NPV) for the early rule-out of acute myocardial infarction (AMI). We hypothesized that a second copeptin measurement at 1 h might further increase the NPV. In a prospective diagnostic multicenter study, we measured hs-cTnT and copeptin concentrations at presentation and at 1 h in 1439 unselected patients presenting to the emergency department with suspected AMI. The final diagnosis was adjudicated by 2 independent cardiologists blinded to copeptin concentrations. We investigated the incremental value of 1-h copeptin in the rule-out setting (0-h hs-cTnT negative and 0-h copeptin negative) and the intermediate-risk setting (0-h hs-cTnT negative and 0-h copeptin positive). The adjudicated diagnosis was AMI in 267 patients (18.6%). For measurements obtained at presentation, the NPV in the rule-out setting was 98.6% (95% CI, 97.4%-99.3%). Whereas 1-h copeptin did not increase the NPV significantly, 1-h hs-cTnT did, to 99.6% (95% CI, 98.7%-99.9%, P = 0.008). Similarly, in the intermediate-risk setting (NPV 92.8%, 95% CI, 88.7%-95.8%), 1-h copeptin did not significantly increase the NPV (P = 0.751), but 1-h hs-cTnT did, to 98.6 (95% CI, 96%-99.7%, P < 0.001). One-hour copeptin increased neither the safety of the rule-out process nor the NPV in the intermediate-risk setting. In contrast, the incremental value of 1-h hs-cTnT was substantial in both settings. ClinicalTrials.gov/NCT00470587. © 2015 American Association for Clinical Chemistry.

Composition Formulas of Inorganic Compounds in Terms of Cluster Plus Glue Atom Model.

PubMed

Ma, Yanping; Dong, Dandan; Wu, Aimin; Dong, Chuang

2018-01-16

The present paper attempts to identify the molecule-like structural units in inorganic compounds, by applying the so-called "cluster plus glue atom model". This model, originating from metallic glasses and quasi-crystals, describes any structure in terms of a nearest-neighbor cluster and a few outer-shell glue atoms, expressed in the cluster formula [cluster](glue atoms). Similar to the case for normal molecules where the charge transfer occurs within the molecule to meet the commonly known octet electron rule, the octet state is reached after matching the nearest-neighbor cluster with certain outer-shell glue atoms. These kinds of structural units contain information on local atomic configuration, chemical composition, and electron numbers, just as for normal molecules. It is shown that the formulas of typical inorganic compounds, such as fluorides, oxides, and nitrides, satisfy a similar octet electron rule, with the total number of valence electrons per unit formula being multiples of eight.

The cost-effectiveness of dapagliflozin versus sulfonylurea as an add-on to metformin in the treatment of Type 2 diabetes mellitus.

PubMed

Charokopou, M; McEwan, P; Lister, S; Callan, L; Bergenheim, K; Tolley, K; Postema, R; Townsend, R; Roudaut, M

2015-07-01

To assess the cost-effectiveness of dapagliflozin, a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, compared with a sulfonylurea, when added to metformin for treatment of UK people with Type 2 diabetes mellitus inadequately controlled on metformin alone. Clinical inputs sourced from a head-to-head randomized controlled trial (RCT) informed the Cardiff diabetes decision model. Risk equations developed from the United Kingdom Prospective Diabetes Study (UKPDS) were used in conjunction with the clinical inputs to predict disease progression and the incidence of micro- and macrovascular complications over a lifetime horizon. Cost and utility data were generated to present the incremental cost-effectiveness ratio (ICER) for both treatment arms, and sensitivity and scenario analyses were conducted to assess the impact of uncertainty on the final model results. The dapagliflozin treatment arm was associated with a mean incremental benefit of 0.467 quality-adjusted life years (QALYs) [95% confidence interval (CI): 0.420; 0.665], with an incremental cost of £1246 (95% CI: £613; £1637). This resulted in an ICER point estimate of £2671 per QALY gained. Incremental costs were shown to be insensitive to parameter variation, with only treatment-related weight change having a significant impact on the incremental QALYs. Probabilistic sensitivity analysis determined that dapagliflozin had a 100% probability of being cost-effective at a willingness-to-pay threshold of £20,000 per QALY. Dapagliflozin in combination with metformin was shown to be a cost-effective treatment option compared with sulfonylurea from a UK healthcare perspective for people with Type 2 diabetes mellitus who are inadequately controlled on metformin monotherapy. © 2015 The Authors. Diabetic Medicine © 2015 Diabetes UK.

Distributed Trust Management for Validating SLA Choreographies

NASA Astrophysics Data System (ADS)

Haq, Irfan Ul; Alnemr, Rehab; Paschke, Adrian; Schikuta, Erich; Boley, Harold; Meinel, Christoph

For business workflow automation in a service-enriched environment such as a grid or a cloud, services scattered across heterogeneous Virtual Organizations (VOs) can be aggregated in a producer-consumer manner, building hierarchical structures of added value. In order to preserve the supply chain, the Service Level Agreements (SLAs) corresponding to the underlying choreography of services should also be incrementally aggregated. This cross-VO hierarchical SLA aggregation requires validation, for which a distributed trust system becomes a prerequisite. Elaborating our previous work on rule-based SLA validation, we propose a hybrid distributed trust model. This new model is based on Public Key Infrastructure (PKI) and reputation-based trust systems. It helps preventing SLA violations by identifying violation-prone services at service selection stage and actively contributes in breach management at the time of penalty enforcement.

77 FR 31683 - Notice of Effective Date of Modifications to a Rule of Origin of the United States-Australia Free...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-29

... Rule of Origin of the United States-Australia Free Trade Agreement AGENCY: Office of the United States... to a product-specific rule of origin under the United States-Australia Free Trade Agreement (USAFTA). SUMMARY: In Proclamation 8334 of December 31, 2008, the President modified the rules of origin for certain...

Assess and Predict Automatic Generation Control Performances for Thermal Power Generation Units Based on Modeling Techniques

NASA Astrophysics Data System (ADS)

Zhao, Yan; Yang, Zijiang; Gao, Song; Liu, Jinbiao

2018-02-01

Automatic generation control(AGC) is a key technology to maintain real time power generation and load balance, and to ensure the quality of power supply. Power grids require each power generation unit to have a satisfactory AGC performance, being specified in two detailed rules. The two rules provide a set of indices to measure the AGC performance of power generation unit. However, the commonly-used method to calculate these indices is based on particular data samples from AGC responses and will lead to incorrect results in practice. This paper proposes a new method to estimate the AGC performance indices via system identification techniques. In addition, a nonlinear regression model between performance indices and load command is built in order to predict the AGC performance indices. The effectiveness of the proposed method is validated through industrial case studies.

Green Infrastructure Tool | EPA Center for Exposure ...

EPA Pesticide Factsheets

2016-03-07

Units option added – SI or US units. Default option is US units Additional options added to FTABLE such as clear FTABLE Significant digits for FTABLE calculations is changed to 5 Previously a default Cd value was used for calculations (under-drain and riser) but now a user-defined value option is given Conversion options added wherever necessary Default values of suction head and hydraulic conductivity are changed based on units selected in infiltration panel Default values of Cd for riser orifice and under-drain textboxes is changed to 0.6. Previously a default increment value of 0.1 is used for all the channel panels but now user can specify the increment

Retrosynthetic Reaction Prediction Using Neural Sequence-to-Sequence Models

PubMed Central

2017-01-01

We describe a fully data driven model that learns to perform a retrosynthetic reaction prediction task, which is treated as a sequence-to-sequence mapping problem. The end-to-end trained model has an encoder–decoder architecture that consists of two recurrent neural networks, which has previously shown great success in solving other sequence-to-sequence prediction tasks such as machine translation. The model is trained on 50,000 experimental reaction examples from the United States patent literature, which span 10 broad reaction types that are commonly used by medicinal chemists. We find that our model performs comparably with a rule-based expert system baseline model, and also overcomes certain limitations associated with rule-based expert systems and with any machine learning approach that contains a rule-based expert system component. Our model provides an important first step toward solving the challenging problem of computational retrosynthetic analysis. PMID:29104927

77 FR 58027 - Approval and Promulgation of Implementation Plans; Florida: New Source Review-Prevention of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

... revision modifies Florida's New Source Review (NSR) Prevention of Significant Deterioration (PSD) permitting regulations to adopt, into the Florida SIP, federal NSR PSD requirements for the fine particulate... Implementation Rule and the 2010 PM 2.5 PSD Increment, Significant Impact [[Page 58028

40 CFR 52.824 - Original identification of plan section.

Code of Federal Regulations, 2010 CFR

2010-07-01

... attainment and unclassified areas of the state (PSD) were submitted on March 9, 1987, by the Iowa Department... review/PSD regulations. (47) Revised Chapters 22 and 23 regulations pertaining to stack height credits..., incorporates by reference revised EPA PSD rules pertaining to NO X increments. (i) Incorporation by reference...

18 CFR 385.1102 - Definitions (Rule 1102).

Code of Federal Regulations, 2010 CFR

2010-04-01

... incrementally priced industrial boiler fuel facilities from section 201 of the NGPA, under the authority of section 206(d) of the NGPA and § 282.206 (industrial boiler fuel facilities exemption); (b) Petitioner... means the Natural Gas Policy Act of 1978; (e) Party means, with respect to a particular petition for...

Estimating the Depth of Stratigraphic Units from Marine Seismic Profiles Using Nonstationary Geostatistics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chihi, Hayet; Galli, Alain; Ravenne, Christian

2000-03-15

The object of this study is to build a three-dimensional (3D) geometric model of the stratigraphic units of the margin of the Rhone River on the basis of geophysical investigations by a network of seismic profiles at sea. The geometry of these units is described by depth charts of each surface identified by seismic profiling, which is done by geostatistics. The modeling starts by a statistical analysis by which we determine the parameters that enable us to calculate the variograms of the identified surfaces. After having determined the statistical parameters, we calculate the variograms of the variable Depth. By analyzingmore » the behavior of the variogram we then can deduce whether the situation is stationary and if the variable has an anisotropic behavior. We tried the following two nonstationary methods to obtain our estimates: (a) The method of universal kriging if the underlying variogram was directly accessible. (b) The method of increments if the underlying variogram was not directly accessible. After having modeled the variograms of the increments and of the variable itself, we calculated the surfaces by kriging the variable Depth on a small-mesh estimation grid. The two methods then are compared and their respective advantages and disadvantages are discussed, as well as their fields of application. These methods are capable of being used widely in earth sciences for automatic mapping of geometric surfaces or for variables such as a piezometric surface or a concentration, which are not 'stationary,' that is, essentially, possess a gradient or a tendency to develop systematically in space.« less

Economic Burden of Attention-Deficit/Hyperactivity Disorder among Pediatric Patients in the United States.

PubMed

Gupte-Singh, Komal; Singh, Rakesh R; Lawson, Kenneth A

2017-04-01

To determine the adjusted incremental total costs (direct and indirect) for patients (aged 3-17 years) with attention-deficit/hyperactivity disorder (ADHD) and the differences in the adjusted incremental direct expenditures with respect to age groups (preschoolers, 0-5 years; children, 6-11 years; and adolescents, 12-17 years). The 2011 Medical Expenditure Panel Survey was used as the data source. The ADHD cohort consisted of patients aged 0 to 17 years with a diagnosis of ADHD, whereas the non-ADHD cohort consisted of subjects in the same age range without a diagnosis of ADHD. The annual incremental total cost of ADHD is composed of the incremental direct expenditures and indirect costs. A two-part model with a logistic regression (first part) and a generalized linear model (second part) was used to estimate the incremental costs of ADHD while controlling for patient characteristics and access-to-care variables. The 2011 Medical Expenditure Panel Survey database included 9108 individuals aged 0 to 17 years, with 458 (5.0%) having an ADHD diagnosis. The ADHD cohort was 4.90 times more likely (95% confidence interval [CI] 2.97-8.08; P < 0.001) than the non-ADHD cohort to have an expenditure of at least $1, and among those with positive expenditures, the ADHD cohort had 58.4% higher expenditures than the non-ADHD cohort (P < 0.001). The estimated adjusted annual total incremental cost of ADHD was $949.24 (95% CI $593.30-$1305.18; P < 0.001). The adjusted annual incremental total direct expenditure for ADHD was higher among preschoolers ($989.34; 95% CI $402.70-$1575.98; P = 0.001) than among adolescents ($894.94; 95% CI $428.16-$1361.71; P < 0.001) or children ($682.71; 95% CI $347.94-$1017.48; P < 0.001). Early diagnosis and use of evidence-based treatments may address the substantial burden of ADHD. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

A fuzzy neural network for intelligent data processing

NASA Astrophysics Data System (ADS)

Xie, Wei; Chu, Feng; Wang, Lipo; Lim, Eng Thiam

2005-03-01

In this paper, we describe an incrementally generated fuzzy neural network (FNN) for intelligent data processing. This FNN combines the features of initial fuzzy model self-generation, fast input selection, partition validation, parameter optimization and rule-base simplification. A small FNN is created from scratch -- there is no need to specify the initial network architecture, initial membership functions, or initial weights. Fuzzy IF-THEN rules are constantly combined and pruned to minimize the size of the network while maintaining accuracy; irrelevant inputs are detected and deleted, and membership functions and network weights are trained with a gradient descent algorithm, i.e., error backpropagation. Experimental studies on synthesized data sets demonstrate that the proposed Fuzzy Neural Network is able to achieve accuracy comparable to or higher than both a feedforward crisp neural network, i.e., NeuroRule, and a decision tree, i.e., C4.5, with more compact rule bases for most of the data sets used in our experiments. The FNN has achieved outstanding results for cancer classification based on microarray data. The excellent classification result for Small Round Blue Cell Tumors (SRBCTs) data set is shown. Compared with other published methods, we have used a much fewer number of genes for perfect classification, which will help researchers directly focus their attention on some specific genes and may lead to discovery of deep reasons of the development of cancers and discovery of drugs.

Soil pH Errors Propagation from Measurements to Spatial Predictions - Cost Benefit Analysis and Risk Assessment Implications for Practitioners and Modelers

NASA Astrophysics Data System (ADS)

Owens, P. R.; Libohova, Z.; Seybold, C. A.; Wills, S. A.; Peaslee, S.; Beaudette, D.; Lindbo, D. L.

2017-12-01

The measurement errors and spatial prediction uncertainties of soil properties in the modeling community are usually assessed against measured values when available. However, of equal importance is the assessment of errors and uncertainty impacts on cost benefit analysis and risk assessments. Soil pH was selected as one of the most commonly measured soil properties used for liming recommendations. The objective of this study was to assess the error size from different sources and their implications with respect to management decisions. Error sources include measurement methods, laboratory sources, pedotransfer functions, database transections, spatial aggregations, etc. Several databases of measured and predicted soil pH were used for this study including the United States National Cooperative Soil Survey Characterization Database (NCSS-SCDB), the US Soil Survey Geographic (SSURGO) Database. The distribution of errors among different sources from measurement methods to spatial aggregation showed a wide range of values. The greatest RMSE of 0.79 pH units was from spatial aggregation (SSURGO vs Kriging), while the measurement methods had the lowest RMSE of 0.06 pH units. Assuming the order of data acquisition based on the transaction distance i.e. from measurement method to spatial aggregation the RMSE increased from 0.06 to 0.8 pH units suggesting an "error propagation". This has major implications for practitioners and modeling community. Most soil liming rate recommendations are based on 0.1 pH unit increments, while the desired soil pH level increments are based on 0.4 to 0.5 pH units. Thus, even when the measured and desired target soil pH are the same most guidelines recommend 1 ton ha-1 lime, which translates in 111 ha-1 that the farmer has to factor in the cost-benefit analysis. However, this analysis need to be based on uncertainty predictions (0.5-1.0 pH units) rather than measurement errors (0.1 pH units) which would translate in 555-1,111 investment that need to be assessed against the risk. The modeling community can benefit from such analysis, however, error size and spatial distribution for global and regional predictions need to be assessed against the variability of other drivers and impact on management decisions.

Hidden electronic rule in the “cluster-plus-glue-atom” model

PubMed Central

Du, Jinglian; Dong, Chuang; Melnik, Roderick; Kawazoe, Yoshiyuki; Wen, Bin

2016-01-01

Electrons and their interactions are intrinsic factors to affect the structure and properties of materials. Based on the “cluster-cluster-plus-glue-atom” model, an electron counting rule for complex metallic alloys (CMAs) has been revealed in this work (i. e. the CPGAMEC rule). Our results on the cluster structure and electron concentration of CMAs with apparent cluster features, indicate that the valence electrons’ number per unit cluster formula for these CMAs are specific constants of eight-multiples and twelve-multiples. It is thus termed as specific electrons cluster formula. This CPGAMEC rule has been demonstrated as a useful guidance to direct the design of CMAs with desired properties, while its practical applications and underlying mechanism have been illustrated on the basis of CMAs’ cluster structural features. Our investigation provides an aggregate picture with intriguing electronic rule and atomic structural features of CMAs. PMID:27642002

The cost-effectiveness of air bags by seating position.

PubMed

Graham, J D; Thompson, K M; Goldie, S J; Segui-Gomez, M; Weinstein, M C

1997-11-05

Motor vehicle crashes continue to cause significant mortality and morbidity in the United States. Installation of air bags in new passenger vehicles is a major initiative in the field of injury prevention. To assess the net health consequences and cost-effectiveness of driver's side and front passenger air bags from a societal perspective, taking into account the increased risk to children who occupy the front passenger seat and the diminished effectiveness for older adults. A deterministic state transition model tracked a hypothetical cohort of new vehicles over a 20-year period for 3 strategies: (1) installation of safety belts, (2) installation of driver's side air bags in addition to safety belts, and (3) installation of front passenger air bags in addition to safety belts and driver's side air bags. Changes in health outcomes, valued in terms of quality-adjusted life-years (QALYs) and costs (in 1993 dollars), were projected following the recommendations of the Panel on Cost-effectiveness in Health and Medicine. US population-based and convenience sample data were used. Incremental cost-effectiveness ratios. Safety belts are cost saving, even at 50% use. The addition of driver's side air bags to safety belts results in net health benefits at an incremental cost of $24000 per QALY saved. The further addition of front passenger air bags results in an incremental net benefit at a higher incremental cost of $61000 per QALY saved. Results were sensitive to the unit cost of air bag systems, their effectiveness, baseline fatality rates, the ratio of injuries to fatalities, and the real discount rate. Both air bag systems save life-years at costs that are comparable to many medical and public health practices. Immediate steps can be taken to enhance the cost-effectiveness of front passenger air bags, such as moving children to the rear seat.

Online blind source separation using incremental nonnegative matrix factorization with volume constraint.

PubMed

Zhou, Guoxu; Yang, Zuyuan; Xie, Shengli; Yang, Jun-Mei

2011-04-01

Online blind source separation (BSS) is proposed to overcome the high computational cost problem, which limits the practical applications of traditional batch BSS algorithms. However, the existing online BSS methods are mainly used to separate independent or uncorrelated sources. Recently, nonnegative matrix factorization (NMF) shows great potential to separate the correlative sources, where some constraints are often imposed to overcome the non-uniqueness of the factorization. In this paper, an incremental NMF with volume constraint is derived and utilized for solving online BSS. The volume constraint to the mixing matrix enhances the identifiability of the sources, while the incremental learning mode reduces the computational cost. The proposed method takes advantage of the natural gradient based multiplication updating rule, and it performs especially well in the recovery of dependent sources. Simulations in BSS for dual-energy X-ray images, online encrypted speech signals, and high correlative face images show the validity of the proposed method.

Thermal elastoplastic structural analysis of non-metallic thermal protection systems

NASA Technical Reports Server (NTRS)

Chung, T. J.; Yagawa, G.

1972-01-01

An incremental theory and numerical procedure to analyze a three-dimensional thermoelastoplastic structure subjected to high temperature, surface heat flux, and volume heat supply as well as mechanical loadings are presented. Heat conduction equations and equilibrium equations are derived by assuming a specific form of incremental free energy, entropy, stresses and heat flux together with the first and second laws of thermodynamics, von Mises yield criteria and Prandtl-Reuss flow rule. The finite element discretization using the linear isotropic three-dimensional element for the space domain and a difference operator corresponding to a linear variation of temperature within a small time increment for the time domain lead to systematic solutions of temperature distribution and displacement and stress fields. Various boundary conditions such as insulated surfaces and convection through uninsulated surface can be easily treated. To demonstrate effectiveness of the present formulation a number of example problems are presented.

40 CFR 60.2630 - What should I include in my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Waste Management.... Model Rule—Operator Training and Qualification ...

40 CFR 60.2630 - What should I include in my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Waste Management.... Model Rule—Operator Training and Qualification ...

An investigation of the use of temporal decomposition in space mission scheduling

NASA Technical Reports Server (NTRS)

Bullington, Stanley E.; Narayanan, Venkat

1994-01-01

This research involves an examination of techniques for solving scheduling problems in long-duration space missions. The mission timeline is broken up into several time segments, which are then scheduled incrementally. Three methods are presented for identifying the activities that are to be attempted within these segments. The first method is a mathematical model, which is presented primarily to illustrate the structure of the temporal decomposition problem. Since the mathematical model is bound to be computationally prohibitive for realistic problems, two heuristic assignment procedures are also presented. The first heuristic method is based on dispatching rules for activity selection, and the second heuristic assigns performances of a model evenly over timeline segments. These heuristics are tested using a sample Space Station mission and a Spacelab mission. The results are compared with those obtained by scheduling the missions without any problem decomposition. The applicability of this approach to large-scale mission scheduling problems is also discussed.

Summary of the Science Performed Onboard the International Space Station within the United States Orbital Segment during Increments 16 and 17

NASA Technical Reports Server (NTRS)

Jules, Kenol; Istasse, Eric; Stenuit, Hilde; Murakami, Jeiji; Yoshizaki, Izumi; Johnson-Green, Perry

2008-01-01

With the launch of the STS-122 on February 7, 2008, which delivered the European Columbus science module and the upcoming STS-124 flight, which will deliver the Japanese Kibo science module in May 2008, the International Space Station will become truly International with Europe and Japan joining the United States of America and Russia to perform science on a continuous basis in a wide spectrum of science disciplines. The last science module, Kibo, of the United States Orbital Segment (USOS) will be mated to the station on time to celebrate its first decade in low Earth orbit in October 2008 (end of Increment 17), thus ushering in the second decade of the station with all the USOS science modules mated and performing science. The arrival of the Kibo science module will also mark continuous human presence on the station for eighty eight (88) months, and, with the addition of the ESA science module during the STS-122 flight, the USOS will be made up of four space agencies: CSA, ESA, JAXA and NASA, spanning three continents. With the additional partners coming onboard with different research needs, every effort is being made to coordinate science across the USOS segment in an integrated manner for the benefit of all parties. One of the objectives of this paper is to discuss the integrated manner in which science planning/replanning and prioritization during the execution phase of an increment is being done. The main focus, though, of this paper is to summarize and to discuss the science performed during Increments 16 and 17 (October 2007 to October 2008). The discussion will focus mainly on the primary objectives of each investigation and their associated hypotheses that were investigated during these two Increments. Also, preliminary science results will be discussed for each of the investigation as science results availability permit. Additionally, the paper will briefly touch on what the science complement for these two increments was and what was actually accomplished due to real time science implementation and constraints. Finally, the paper will briefly discuss the science research complements for the next three Increments: Increments 18 to 20, in order to preview how much science might be accomplished during these three upcoming Increments of the station next decade.

Strategic Impact of Cyber Warfare Rules for the United States

DTIC Science & Technology

2010-03-01

Despite the growing complexities of cyberspace and the significant strategic challenge cyber warfare poses on the United States’ vital interests few...specific rules for cyber warfare exist. The United States should seek to develop and maintain cyber warfare rules in order to establish...exemplify the need for multilaterally prepared cyber warfare rules that will reduce the negative influence cyber warfare presently has on the United States’ national interests.

75 FR 68153 - To Adjust the Rules of Origin Under the United States-Bahrain Free Trade Agreement, Implement...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-04

... Part IV The President Proclamation 8596--To Adjust the Rules of Origin Under the United States... Adjust the Rules of Origin Under the United States-Bahrain Free Trade Agreement, Implement Modifications... the HTS the schedule of duty reductions and rules of origin necessary or appropriate to carry out the...

Parallel multi-join query optimization algorithm for distributed sensor network in the internet of things

NASA Astrophysics Data System (ADS)

Zheng, Yan

2015-03-01

Internet of things (IoT), focusing on providing users with information exchange and intelligent control, attracts a lot of attention of researchers from all over the world since the beginning of this century. IoT is consisted of large scale of sensor nodes and data processing units, and the most important features of IoT can be illustrated as energy confinement, efficient communication and high redundancy. With the sensor nodes increment, the communication efficiency and the available communication band width become bottle necks. Many research work is based on the instance which the number of joins is less. However, it is not proper to the increasing multi-join query in whole internet of things. To improve the communication efficiency between parallel units in the distributed sensor network, this paper proposed parallel query optimization algorithm based on distribution attributes cost graph. The storage information relations and the network communication cost are considered in this algorithm, and an optimized information changing rule is established. The experimental result shows that the algorithm has good performance, and it would effectively use the resource of each node in the distributed sensor network. Therefore, executive efficiency of multi-join query between different nodes could be improved.

Modern high powered led curing lights and their effect on pulp chamber temperature of bulk and incrementally cured composite resin.

PubMed

Oberholzer, T G; Makofane, M E; du Preez, I C; George, R

2012-06-01

Pulpal temperature changes induced by modern high powered light emitting diodes (LEDs) are of concern when used to cure composite resins. This study showed an increase in pulp chamber temperature with an increase in power density for all light cure units (LCU) when used to bulk cure composite resin. Amongst the three LEDs tested, the Elipar Freelight-2 recorded the highest temperature changes. Bulk curing recorded a significantly larger rise in pulp chamber temperature change than incrementally cured resin for all light types except for the Smartligh PS. Both the high powered LED and the conventional curing units can generate heat. Though this temperature rise may not be sufficient to cause irreversible pulpal damage, it would be safer to incrementally cure resins.

40 CFR 60.2695 - How are the performance test data used?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Performance Testing.... [76 FR 15773, Mar. 21, 2011] Model Rule—Initial Compliance Requirements ...

40 CFR 60.2695 - How are the performance test data used?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Performance Testing.... [76 FR 15773, Mar. 21, 2011] Model Rule—Initial Compliance Requirements ...

Combining density functional and incremental post-Hartree-Fock approaches for van der Waals dominated adsorbate-surface interactions: Ag{sub 2}/graphene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lara-Castells, María Pilar de, E-mail: Pilar.deLara.Castells@csic.es; Mitrushchenkov, Alexander O.; Stoll, Hermann

2015-09-14

A combined density functional (DFT) and incremental post-Hartree-Fock (post-HF) approach, proven earlier to calculate He-surface potential energy surfaces [de Lara-Castells et al., J. Chem. Phys. 141, 151102 (2014)], is applied to describe the van der Waals dominated Ag{sub 2}/graphene interaction. It extends the dispersionless density functional theory developed by Pernal et al. [Phys. Rev. Lett. 103, 263201 (2009)] by including periodic boundary conditions while the dispersion is parametrized via the method of increments [H. Stoll, J. Chem. Phys. 97, 8449 (1992)]. Starting with the elementary cluster unit of the target surface (benzene), continuing through the realistic cluster model (coronene), andmore » ending with the periodic model of the extended system, modern ab initio methodologies for intermolecular interactions as well as state-of-the-art van der Waals-corrected density functional-based approaches are put together both to assess the accuracy of the composite scheme and to better characterize the Ag{sub 2}/graphene interaction. The present work illustrates how the combination of DFT and post-HF perspectives may be efficient to design simple and reliable ab initio-based schemes in extended systems for surface science applications.« less

An efficient incremental learning mechanism for tracking concept drift in spam filtering

PubMed Central

Sheu, Jyh-Jian; Chu, Ko-Tsung; Li, Nien-Feng; Lee, Cheng-Chi

2017-01-01

This research manages in-depth analysis on the knowledge about spams and expects to propose an efficient spam filtering method with the ability of adapting to the dynamic environment. We focus on the analysis of email’s header and apply decision tree data mining technique to look for the association rules about spams. Then, we propose an efficient systematic filtering method based on these association rules. Our systematic method has the following major advantages: (1) Checking only the header sections of emails, which is different from those spam filtering methods at present that have to analyze fully the email’s content. Meanwhile, the email filtering accuracy is expected to be enhanced. (2) Regarding the solution to the problem of concept drift, we propose a window-based technique to estimate for the condition of concept drift for each unknown email, which will help our filtering method in recognizing the occurrence of spam. (3) We propose an incremental learning mechanism for our filtering method to strengthen the ability of adapting to the dynamic environment. PMID:28182691

Leaf area and light use efficiency patterns of Norway spruce under different thinning regimes and age classes

PubMed Central

Gspaltl, Martin; Bauerle, William; Binkley, Dan; Sterba, Hubert

2013-01-01

Silviculture focuses on establishing forest stand conditions that improve the stand increment. Knowledge about the efficiency of an individual tree is essential to be able to establish stand structures that increase tree resource use efficiency and stand level production. Efficiency is often expressed as stem growth per unit leaf area (leaf area efficiency), or per unit of light absorbed (light use efficiency). We tested the hypotheses that: (1) volume increment relates more closely with crown light absorption than leaf area, since one unit of leaf area can receive different amounts of light due to competition with neighboring trees and self-shading, (2) dominant trees use light more efficiently than suppressed trees and (3) thinning increases the efficiency of light use by residual trees, partially accounting for commonly observed increases in post-thinning growth. We investigated eight even-aged Norway spruce (Picea abies (L.) Karst.) stands at Bärnkopf, Austria, spanning three age classes (mature, immature and pole-stage) and two thinning regimes (thinned and unthinned). Individual leaf area was calculated with allometric equations and absorbed photosynthetically active radiation was estimated for each tree using the three-dimensional crown model Maestra. Absorbed photosynthetically active radiation was only a slightly better predictor of volume increment than leaf area. Light use efficiency increased with increasing tree size in all stands, supporting the second hypothesis. At a given tree size, trees from the unthinned plots were more efficient, however, due to generally larger tree sizes in the thinned stands, an average tree from the thinned treatment was superior (not congruent in all plots, thus only partly supporting the third hypothesis). PMID:25540477

40 CFR 60.2720 - May I conduct performance testing less often?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Continuous...

40 CFR 60.2720 - May I conduct performance testing less often?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Continuous...

A comparative study of velocity increment generation between the rigid body and flexible models of MMET

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ismail, Norilmi Amilia, E-mail: aenorilmi@usm.my

The motorized momentum exchange tether (MMET) is capable of generating useful velocity increments through spin–orbit coupling. This study presents a comparative study of the velocity increments between the rigid body and flexible models of MMET. The equations of motions of both models in the time domain are transformed into a function of true anomaly. The equations of motion are integrated, and the responses in terms of the velocity increment of the rigid body and flexible models are compared and analysed. Results show that the initial conditions, eccentricity, and flexibility of the tether have significant effects on the velocity increments ofmore » the tether.« less

77 FR 72885 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... JUDICIAL CONFERENCE OF THE UNITED STATES Meeting of the Judicial Conference Committee on Rules of Practice and Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of... CONTACT: Jonathan C. Rose, Secretary and Chief Rules Officer, Rules Committee Support Office...

40 CFR 60.3042 - How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units?

Code of Federal Regulations, 2012 CFR

2012-07-01

... averages into the appropriate averaging times and units? 60.3042 Section 60.3042 Protection of Environment... Construction On or Before December 9, 2004 Model Rule-Monitoring § 60.3042 How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units? (a) Use Equation 1 in § 60.3076 to...

40 CFR 60.3042 - How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units?

Code of Federal Regulations, 2010 CFR

2010-07-01

... averages into the appropriate averaging times and units? 60.3042 Section 60.3042 Protection of Environment... Construction On or Before December 9, 2004 Model Rule-Monitoring § 60.3042 How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units? (a) Use Equation 1 in § 60.3076 to...

40 CFR 60.3042 - How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units?

Code of Federal Regulations, 2013 CFR

2013-07-01

... averages into the appropriate averaging times and units? 60.3042 Section 60.3042 Protection of Environment... Construction On or Before December 9, 2004 Model Rule-Monitoring § 60.3042 How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units? (a) Use Equation 1 in § 60.3076 to...

40 CFR 60.3042 - How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units?

Code of Federal Regulations, 2011 CFR

2011-07-01

... averages into the appropriate averaging times and units? 60.3042 Section 60.3042 Protection of Environment... Construction On or Before December 9, 2004 Model Rule-Monitoring § 60.3042 How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units? (a) Use Equation 1 in § 60.3076 to...

40 CFR 60.3042 - How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units?

Code of Federal Regulations, 2014 CFR

2014-07-01

... averages into the appropriate averaging times and units? 60.3042 Section 60.3042 Protection of Environment... Construction On or Before December 9, 2004 Model Rule-Monitoring § 60.3042 How do I convert my 1-hour arithmetic averages into the appropriate averaging times and units? (a) Use Equation 1 in § 60.3076 to...

Habitat Suitability Index Models: Yellow perch

USGS Publications Warehouse

Krieger, Douglas A.; Terrell, James W.; Nelson, Patrick C.

1983-01-01

A review and synthesis of existing information were used to develop riverine and lacustrine habitat models for yellow perch (Perca flavescens). The models are scaled to produce an index of habitat suitability between 0 (unsuitable habitat) to 1 (optimally suitable habitat) for riverine, lacustrine, and palustrine habitat in the 48 contiguous United States. Habitat Suitability Indexes (HSI's) are designed for use with the Habitat Evaluation Procedures developed by the U.S. Fish and Wildlife Service. Also included are discussions of Suitability Index (SI) curves as used in the Instream Flow Incremental Methodology (IFIM) and SI curves available for an IFIM analysis of yellow perch habitat.

Verification and Validation of KBS with Neural Network Components

NASA Technical Reports Server (NTRS)

Wen, Wu; Callahan, John

1996-01-01

Artificial Neural Network (ANN) play an important role in developing robust Knowledge Based Systems (KBS). The ANN based components used in these systems learn to give appropriate predictions through training with correct input-output data patterns. Unlike traditional KBS that depends on a rule database and a production engine, the ANN based system mimics the decisions of an expert without specifically formulating the if-than type of rules. In fact, the ANNs demonstrate their superiority when such if-then type of rules are hard to generate by human expert. Verification of traditional knowledge based system is based on the proof of consistency and completeness of the rule knowledge base and correctness of the production engine.These techniques, however, can not be directly applied to ANN based components.In this position paper, we propose a verification and validation procedure for KBS with ANN based components. The essence of the procedure is to obtain an accurate system specification through incremental modification of the specifications using an ANN rule extraction algorithm.

40 CFR 60.1680 - After the required date for operator certification, who may operate the municipal waste...

Code of Federal Regulations, 2012 CFR

2012-07-01

... certification, who may operate the municipal waste combustion unit? 60.1680 Section 60.1680 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operator...

40 CFR 60.1680 - After the required date for operator certification, who may operate the municipal waste...

Code of Federal Regulations, 2011 CFR

2011-07-01

... certification, who may operate the municipal waste combustion unit? 60.1680 Section 60.1680 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operator...

40 CFR 60.1680 - After the required date for operator certification, who may operate the municipal waste...

Code of Federal Regulations, 2013 CFR

2013-07-01

... certification, who may operate the municipal waste combustion unit? 60.1680 Section 60.1680 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operator...

40 CFR 60.1680 - After the required date for operator certification, who may operate the municipal waste...

Code of Federal Regulations, 2014 CFR

2014-07-01

... certification, who may operate the municipal waste combustion unit? 60.1680 Section 60.1680 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operator...

40 CFR 60.1680 - After the required date for operator certification, who may operate the municipal waste...

Code of Federal Regulations, 2010 CFR

2010-07-01

... certification, who may operate the municipal waste combustion unit? 60.1680 Section 60.1680 Protection of... NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Good Combustion Practices: Operator...

40 CFR 60.1865 - What are the appropriate units of measurement for reporting my data?

Code of Federal Regulations, 2010 CFR

2010-07-01

... measurement for reporting my data? 60.1865 Section 60.1865 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission..., 1999 Model Rule-Reporting § 60.1865 What are the appropriate units of measurement for reporting my data...

75 FR 9265 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-01

... subject to certain conflict of interest provisions set forth in NYSE Amex Equities Rules 1603 and 1604. NYSE Amex Equities Rule 1603 provides that, if a DMM unit is operating under Rule 98 (Former)--NYSE... Amex Equities Rule 1603 provides that, if a DMM unit is operating under Rule 98--NYSE Amex Equities...

40 CFR 60.2645 - How do I obtain my operator qualification?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training...

40 CFR 60.2650 - How do I maintain my operator qualification?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training...

40 CFR 60.2650 - How do I maintain my operator qualification?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training...

40 CFR 60.2645 - How do I obtain my operator qualification?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training...

Fuzzy Q-Learning for Generalization of Reinforcement Learning

NASA Technical Reports Server (NTRS)

Berenji, Hamid R.

1996-01-01

Fuzzy Q-Learning, introduced earlier by the author, is an extension of Q-Learning into fuzzy environments. GARIC is a methodology for fuzzy reinforcement learning. In this paper, we introduce GARIC-Q, a new method for doing incremental Dynamic Programming using a society of intelligent agents which are controlled at the top level by Fuzzy Q-Learning and at the local level, each agent learns and operates based on GARIC. GARIC-Q improves the speed and applicability of Fuzzy Q-Learning through generalization of input space by using fuzzy rules and bridges the gap between Q-Learning and rule based intelligent systems.

Dedicated outreach service for hard to reach patients with tuberculosis in London: observational study and economic evaluation

PubMed Central

Jit, Mark; Stagg, Helen R; Aldridge, Robert W; White, Peter J

2011-01-01

Objective To assess the cost effectiveness of the Find and Treat service for diagnosing and managing hard to reach individuals with active tuberculosis. Design Economic evaluation using a discrete, multiple age cohort, compartmental model of treated and untreated cases of active tuberculosis. Setting London, United Kingdom. Population Hard to reach individuals with active pulmonary tuberculosis screened or managed by the Find and Treat service (48 mobile screening unit cases, 188 cases referred for case management support, and 180 cases referred for loss to follow-up), and 252 passively presenting controls from London’s enhanced tuberculosis surveillance system. Main outcome measures Incremental costs, quality adjusted life years (QALYs), and cost effectiveness ratios for the Find and Treat service. Results The model estimated that, on average, the Find and Treat service identifies 16 and manages 123 active cases of tuberculosis each year in hard to reach groups in London. The service has a net cost of £1.4 million/year and, under conservative assumptions, gains 220 QALYs. The incremental cost effectiveness ratio was £6400-£10 000/QALY gained (about €7300-€11 000 or $10 000-$16 000 in September 2011). The two Find and Treat components were also cost effective, even in unfavourable scenarios (mobile screening unit (for undiagnosed cases), £18 000-£26 000/QALY gained; case management support team, £4100-£6800/QALY gained). Conclusions Both the screening and case management components of the Find and Treat service are likely to be cost effective in London. The cost effectiveness of the mobile screening unit in particular could be even greater than estimated, in view of the secondary effects of infection transmission and development of antibiotic resistance. PMID:22067473

Dedicated outreach service for hard to reach patients with tuberculosis in London: observational study and economic evaluation.

PubMed

Jit, Mark; Stagg, Helen R; Aldridge, Robert W; White, Peter J; Abubakar, Ibrahim

2011-09-14

To assess the cost effectiveness of the Find and Treat service for diagnosing and managing hard to reach individuals with active tuberculosis. Economic evaluation using a discrete, multiple age cohort, compartmental model of treated and untreated cases of active tuberculosis. London, United Kingdom. Population Hard to reach individuals with active pulmonary tuberculosis screened or managed by the Find and Treat service (48 mobile screening unit cases, 188 cases referred for case management support, and 180 cases referred for loss to follow-up), and 252 passively presenting controls from London's enhanced tuberculosis surveillance system. Incremental costs, quality adjusted life years (QALYs), and cost effectiveness ratios for the Find and Treat service. The model estimated that, on average, the Find and Treat service identifies 16 and manages 123 active cases of tuberculosis each year in hard to reach groups in London. The service has a net cost of £1.4 million/year and, under conservative assumptions, gains 220 QALYs. The incremental cost effectiveness ratio was £6400-£10,000/QALY gained (about €7300-€11,000 or $10,000-$16 000 in September 2011). The two Find and Treat components were also cost effective, even in unfavourable scenarios (mobile screening unit (for undiagnosed cases), £18,000-£26,000/QALY gained; case management support team, £4100-£6800/QALY gained). Both the screening and case management components of the Find and Treat service are likely to be cost effective in London. The cost effectiveness of the mobile screening unit in particular could be even greater than estimated, in view of the secondary effects of infection transmission and development of antibiotic resistance.

Cost effectiveness of recombinant activated factor VII for the control of bleeding in patients with severe blunt trauma injuries in the United Kingdom.

PubMed

Morris, S; Ridley, S; Munro, V; Christensen, M C

2007-01-01

The aim of this study was to assess the lifetime cost effectiveness of recombinant activated factor VII vs placebo as adjunctive therapy for control of bleeding in patients with severe blunt trauma in the UK. We developed a cost-effectiveness model based on patient level data from a 30-day international, randomised, placebo-controlled Phase II trial. The data were supplemented with secondary data from UK sources to estimate lifetime costs and benefits. The model produced a baseline estimate of the incremental cost per life year gained with recombinant activated factor VII relative to placebo of 12 613 UK pounds. The incremental cost per quality adjusted life year gained was 18 825 UK pounds. These estimates are sensitive to the choice of discount rate and health state utility values used. Preliminary results suggest that relative to placebo, recombinant activated factor VII may be a cost-effective therapy to the UK National Health Service.

5 CFR 3101.111 - Additional rules for United States Secret Service employees. [Reserved

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Additional rules for United States Secret Service employees. [Reserved] 3101.111 Section 3101.111 Administrative Personnel DEPARTMENT OF THE....111 Additional rules for United States Secret Service employees. [Reserved] ...

5 CFR 3101.111 - Additional rules for United States Secret Service employees. [Reserved

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Additional rules for United States Secret Service employees. [Reserved] 3101.111 Section 3101.111 Administrative Personnel DEPARTMENT OF THE....111 Additional rules for United States Secret Service employees. [Reserved] ...

5 CFR 3101.111 - Additional rules for United States Secret Service employees. [Reserved

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Additional rules for United States Secret Service employees. [Reserved] 3101.111 Section 3101.111 Administrative Personnel DEPARTMENT OF THE....111 Additional rules for United States Secret Service employees. [Reserved] ...

5 CFR 3101.111 - Additional rules for United States Secret Service employees. [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Additional rules for United States Secret Service employees. [Reserved] 3101.111 Section 3101.111 Administrative Personnel DEPARTMENT OF THE....111 Additional rules for United States Secret Service employees. [Reserved] ...

5 CFR 3101.111 - Additional rules for United States Secret Service employees. [Reserved

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Additional rules for United States Secret Service employees. [Reserved] 3101.111 Section 3101.111 Administrative Personnel DEPARTMENT OF THE....111 Additional rules for United States Secret Service employees. [Reserved] ...

Economics and the 1995 National Assessment of United States Oil and Gas Resources

USGS Publications Warehouse

Attanasi, E.D.

1998-01-01

This report summarizes the economic component of the 1995 National Assessment of Oil and Gas Resources prepared by the U.S. Geological Survey for onshore and State offshore areas of the United States. Province and regional incremental cost functions for conventional undiscovered oil and gas fields, and selected unconventional oil and gas accumulations, allowing the ranking of areas by the incremental costs finding, developing, and producing these resources. Regional projections of additions to reserves from previously discovered fields to 2015 are also presented.

A probabilistic method to diagnose faults of air handling units

NASA Astrophysics Data System (ADS)

Dey, Debashis

Air handling unit (AHU) is one of the most extensively used equipment in large commercial buildings. This device is typically customized and lacks quality system integration which can result in hardwire failures and controller errors. Air handling unit Performance Assessment Rules (APAR) is a fault detection tool that uses a set of expert rules derived from mass and energy balances to detect faults in air handling units. APAR is computationally simple enough that it can be embedded in commercial building automation and control systems and relies only upon sensor data and control signals that are commonly available in these systems. Although APAR has many advantages over other methods, for example no training data required and easy to implement commercially, most of the time it is unable to provide the diagnosis of the faults. For instance, a fault on temperature sensor could be fixed bias, drifting bias, inappropriate location, complete failure. Also a fault in mixing box can be return and outdoor damper leak or stuck. In addition, when multiple rules are satisfied the list of faults increases. There is no proper way to have the correct diagnosis for rule based fault detection system. To overcome this limitation we proposed Bayesian Belief Network (BBN) as a diagnostic tool. BBN can be used to simulate diagnostic thinking of FDD experts through a probabilistic way. In this study we developed a new way to detect and diagnose faults in AHU through combining APAR rules and Bayesian Belief network. Bayesian Belief Network is used as a decision support tool for rule based expert system. BBN is highly capable to prioritize faults when multiple rules are satisfied simultaneously. Also it can get information from previous AHU operating conditions and maintenance records to provide proper diagnosis. The proposed model is validated with real time measured data of a campus building at University of Texas at San Antonio (UTSA).The results show that BBN is correctly able to prioritize faults which can be verified by manual investigation.

A System to Derive Optimal Tree Diameter Increment Models from the Eastwide Forest Inventory Data Base (EFIDB)

Treesearch

Don C. Bragg

2002-01-01

This article is an introduction to the computer software used by the Potential Relative Increment (PRI) approach to optimal tree diameter growth modeling. These DOS programs extract qualified tree and plot data from the Eastwide Forest Inventory Data Base (EFIDB), calculate relative tree increment, sort for the highest relative increments by diameter class, and...

40 CFR 60.2755 - When must I submit my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and...

40 CFR 60.2780 - What must I include in the deviation report?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and...

40 CFR 60.2740 - What records must I keep?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2740...

40 CFR 60.2750 - What reports must I submit?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2750...

40 CFR 60.2755 - When must I submit my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and...

40 CFR 60.2780 - What must I include in the deviation report?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and...

40 CFR 60.2625 - When must I submit my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Waste Management...

40 CFR 60.2740 - What records must I keep?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2740...

40 CFR 60.2750 - What reports must I submit?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2750...

40 CFR 60.2625 - When must I submit my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Waste Management...

Cost-effectiveness of obinutuzumab for chronic lymphocytic leukaemia in The Netherlands.

PubMed

Blommestein, Hedwig M; de Groot, Saskia; Aarts, Mieke J; Vemer, Pepijn; de Vries, Robin; van Abeelen, Annet F M; Posthuma, E F M Ward; Uyl-de Groot, Carin A

2016-11-01

Obinutuzumab combined with chlorambucil (GClb) has shown to be superior to rituximab combined with chlorambucil (RClb) and chlorambucil (Clb) in newly diagnosed patients with chronic lymphocytic leukaemia (CLL). This study evaluates the cost-effectiveness per life-year and quality-adjusted life-year (QALY) of GClb compared to RClb, Clb, and ofatumumab plus chlorambucil (OClb) in The Netherlands. A Markov model was developed to assess the cost-effectiveness of GClb, RClb, Clb and other treatments in the United Kingdom. A country adaptation was made to estimate the cost-effectiveness of these therapies in The Netherlands using Dutch unit costs and Dutch data sources for background mortality and post-progression survival. An incremental gain of 1.06 and 0.64 QALYs was estimated for GClb compared to Clb and RClb respectively, at additional costs of €23,208 and €7254 per patient. Corresponding incremental cost-effectiveness ratios (ICERs) were €21,823 and €11,344 per QALY. Indirect treatment comparisons showed an incremental gain varying from 0.44 to 0.77 QALYs for GClb compared to OClb and additional costs varying from €7041 to €5028 per patient. The ICER varied from €6556 to €16,180 per QALY. Sensitivity analyses showed the robustness of the results. GClb appeared to be a cost-effective treatment strategy compared to RClb, OClb and Clb. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Estimating the staffing infrastructure for a patient-centered medical home.

PubMed

Patel, Mitesh S; Arron, Martin J; Sinsky, Thomas A; Green, Eric H; Baker, David W; Bowen, Judith L; Day, Susan

2013-06-01

The patient-centered medical home (PCMH) offers an innovative method of delivering primary care. However, the necessary staffing infrastructure is not well established. To evaluate the roles of personnel within a PCMH and to propose necessary staffing ratios and associated incremental costs to implement this model of care. We sampled primary care clinical practices that either have successfully deployed or were in the process of implementing a PCMH practice model. We conducted targeted interviews of administrators from these practices and reviewed published literature on the personnel roles within a PCMH. Collectively, these data were compared with current staffing standards and used to inform an analytical model and sensitivity analysis. Primary care practices that successfully transitioned to a PCMH have incorporated a range of new staff and functionalities. Based on our model, we estimated that 4.25 full-time equivalents (FTEs) should be allocated to staffing personnel per 1 physician FTE. Compared with the base-case model of current staffing in the United States of 2.68 FTEs per physician FTE, this is a 59% increase. After applying sensitivity analysis for variability in staffing and compensation, the incremental staffing FTE per physician FTE was 1.57 (range 1.41-1.73) and the incremental associated cost per member per month was $4.68 (range $3.79-$6.43). Our study suggests that additional staff with specific expertise and training is necessary to implement a PCMH. Further study and opportunities for funding additional staffing costs will be important for realizing the potential of the PCMH model of care.influence clinical recognition of depression among diabetes patients from different racial/ethnic groups, and the potential impact of low rates of clinical recognition on quality of care.

Efficient Grammar Induction Algorithm with Parse Forests from Real Corpora

NASA Astrophysics Data System (ADS)

Kurihara, Kenichi; Kameya, Yoshitaka; Sato, Taisuke

The task of inducing grammar structures has received a great deal of attention. The reasons why researchers have studied are different; to use grammar induction as the first stage in building large treebanks or to make up better language models. However, grammar induction has inherent computational complexity. To overcome it, some grammar induction algorithms add new production rules incrementally. They refine the grammar while keeping their computational complexity low. In this paper, we propose a new efficient grammar induction algorithm. Although our algorithm is similar to algorithms which learn a grammar incrementally, our algorithm uses the graphical EM algorithm instead of the Inside-Outside algorithm. We report results of learning experiments in terms of learning speeds. The results show that our algorithm learns a grammar in constant time regardless of the size of the grammar. Since our algorithm decreases syntactic ambiguities in each step, our algorithm reduces required time for learning. This constant-time learning considerably affects learning time for larger grammars. We also reports results of evaluation of criteria to choose nonterminals. Our algorithm refines a grammar based on a nonterminal in each step. Since there can be several criteria to decide which nonterminal is the best, we evaluate them by learning experiments.

77 FR 4169 - Endangered and Threatened Species: Final Rule To Revise the Critical Habitat Designation for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-26

..., we have decided it is not feasible to provide meaningful quantitative estimates of the incremental... potential economic impacts to oil spill response. This revision (i.e., replacing quantitative costs with a... and separate PCE in this final designation. As more research is completed, and we learn more of the...

76 FR 79231 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... Extend the Penny Pilot Program December 15, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange... Chapter V, Section 33 (Penny Pilot Program) of the Rules of the Boston Options Exchange Group, LLC (``BOX... penny increments on BOX (``Penny Pilot Program''). II. Self-Regulatory Organization's Statement of the...

75 FR 76064 - Self-Regulatory Organizations; the NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-07

... Proposed Rule Change Relating to Extension of the Exchange's Penny Pilot Program and Replacement, on a Semi-Annual Basis, of Penny Pilot Issues That Have Been Delisted November 30, 2010. Pursuant to Section 19(b... 5 (Minimum Increments) to: Extend through December 31, 2011, the Penny Pilot Program in options...

77 FR 40127 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... Proposed Rule Change Relating to Extension of the Exchange's Penny Pilot Program and Replacement of Penny... amend Chapter VI, Section 5 (Minimum Increments) to: Extend through December 31, 2012, the Penny Pilot Program in options classes in certain issues (``Penny Pilot'' or ``Pilot''); and provide for or allow...

Rapid Development of Custom Software Architecture Design Environments

DTIC Science & Technology

1999-08-01

the tools themselves. This dissertation describes a new approach to capturing and using architectural design expertise in software architecture design environments...A language and tools are presented for capturing and encapsulating software architecture design expertise within a conceptual framework...of architectural styles and design rules. The design expertise thus captured is supported with an incrementally configurable software architecture

40 CFR 60.2640 - When must the operator training course be completed?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator...

40 CFR 60.2640 - When must the operator training course be completed?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator...

40 CFR 60.3000 - When must I comply?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Waste Incineration Units That Commenced Construction On or Before December 9, 2004 Model Rule-Compliance..., postmarked within 10 business days after the final compliance date in table 1 of this subpart. ...

40 CFR Table 3 to Subpart Bbbb of... - Model Rule-Class I Nitrogen Oxides Emission Limits for Existing Small Municipal Waste Combustion...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Emission Limits for Existing Small Municipal Waste Combustion Units a b c 3 Table 3 to Subpart BBBB of Part... Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Pt. 60, Subpt. BBBB, Table 3 Table... Municipal Waste Combustion Units a b c Municipal waste combustion technology Limits for class I municipal...

Cost-effectiveness of population based BRCA testing with varying Ashkenazi Jewish ancestry.

PubMed

Manchanda, Ranjit; Patel, Shreeya; Antoniou, Antonis C; Levy-Lahad, Ephrat; Turnbull, Clare; Evans, D Gareth; Hopper, John L; Macinnis, Robert J; Menon, Usha; Jacobs, Ian; Legood, Rosa

2017-11-01

Population-based BRCA1/BRCA2 testing has been found to be cost-effective compared with family history-based testing in Ashkenazi-Jewish women were >30 years old with 4 Ashkenazi-Jewish grandparents. However, individuals may have 1, 2, or 3 Ashkenazi-Jewish grandparents, and cost-effectiveness data are lacking at these lower BRCA prevalence estimates. We present an updated cost-effectiveness analysis of population BRCA1/BRCA2 testing for women with 1, 2, and 3 Ashkenazi-Jewish grandparents. Decision analysis model. Lifetime costs and effects of population and family history-based testing were compared with the use of a decision analysis model. 56% BRCA carriers are missed by family history criteria alone. Analyses were conducted for United Kingdom and United States populations. Model parameters were obtained from the Genetic Cancer Prediction through Population Screening trial and published literature. Model parameters and BRCA population prevalence for individuals with 3, 2, or 1 Ashkenazi-Jewish grandparent were adjusted for the relative frequency of BRCA mutations in the Ashkenazi-Jewish and general populations. Incremental cost-effectiveness ratios were calculated for all Ashkenazi-Jewish grandparent scenarios. Costs, along with outcomes, were discounted at 3.5%. The time horizon of the analysis is "life-time," and perspective is "payer." Probabilistic sensitivity analysis evaluated model uncertainty. Population testing for BRCA mutations is cost-saving in Ashkenazi-Jewish women with 2, 3, or 4 grandparents (22-33 days life-gained) in the United Kingdom and 1, 2, 3, or 4 grandparents (12-26 days life-gained) in the United States populations, respectively. It is also extremely cost-effective in women in the United Kingdom with just 1 Ashkenazi-Jewish grandparent with an incremental cost-effectiveness ratio of £863 per quality-adjusted life-years and 15 days life gained. Results show that population-testing remains cost-effective at the £20,000-30000 per quality-adjusted life-years and $100,000 per quality-adjusted life-years willingness-to-pay thresholds for all 4 Ashkenazi-Jewish grandparent scenarios, with ≥95% simulations found to be cost-effective on probabilistic sensitivity analysis. Population-testing remains cost-effective in the absence of reduction in breast cancer risk from oophorectomy and at lower risk-reducing mastectomy (13%) or risk-reducing salpingo-oophorectomy (20%) rates. Population testing for BRCA mutations with varying levels of Ashkenazi-Jewish ancestry is cost-effective in the United Kingdom and the United States. These results support population testing in Ashkenazi-Jewish women with 1-4 Ashkenazi-Jewish grandparent ancestry. Copyright © 2017 Elsevier Inc. All rights reserved.

Renal Replacement Therapy and Incremental Hemodialysis for Veterans with Advanced Chronic Kidney Disease

PubMed Central

Kalantar-Zadeh, Kamyar; Crowley, Susan T.; Beddhu, Srinivasan; Chen, Joline LT; Daugirdas, John T; Goldfarb, David S.; Jin, Anna; Kovesdy, Csaba P.; Leehey, David J.; Moradi, Hamid; Navaneethan, Sankar D; Norris, Keith C; Obi, Yoshitsugu; O’Hare, Ann; Shafi, Tariq; Streja, Elani; Unruh, Mark L.; Vachharajani, Tushar; Weisbord, Steven; Rhee, Connie M.

2017-01-01

Each year approximately 13,000 Veterans transition to maintenance dialysis, mostly in the traditional form of thrice-weekly hemodialysis from the start. Among >6,000 dialysis units nationwide, there are currently approximately 70 Veterans Affairs (VA) dialysis centers. Given this number of VA dialysis centers and their limited capacity, only 10% of all incident dialysis Veterans initiate treatment in a VA center. Evidence suggests that, among Veterans, receipt of care within the VA system is associated with favorable outcomes, potentially due to enhanced access to healthcare resources. Data from the United States Renal Data System Special Study Center “Transition-of-Care-in-CKD” suggest that Veterans who receive dialysis in a VA unit exhibit greater survival compared to non-VA centers. Substantial financial expenditures arise from the high volume of outsourced care and higher dialysis reimbursement paid by the VA than by Medicare to outsourced providers. Given the exceedingly high mortality and abrupt decline in residual kidney function (RKF) in the first dialysis year, it is possible that incremental transition to dialysis through an initial twice-weekly hemodialysis regimen preserves RKF, prolongs vascular access longevity, improves patients’ quality of life, and is a more patient-centered approach and consistent with “personalized” dialysis. Broad implementation of incremental dialysis may also result in more Veterans receiving care within a VA dialysis unit. Controlled trials are urgently needed to examine safety and efficacy of incremental hemodialysis in Veterans and other populations, and the administrative and health care as well as provider structure within the VA system would facilitate the performance of such trials. PMID:28421638

Quasi-static incremental behavior of granular materials: Elastic-plastic coupling and micro-scale dissipation

NASA Astrophysics Data System (ADS)

Kuhn, Matthew R.; Daouadji, Ali

2018-05-01

The paper addresses a common assumption of elastoplastic modeling: that the recoverable, elastic strain increment is unaffected by alterations of the elastic moduli that accompany loading. This assumption is found to be false for a granular material, and discrete element (DEM) simulations demonstrate that granular materials are coupled materials at both micro- and macro-scales. Elasto-plastic coupling at the macro-scale is placed in the context of thermomechanics framework of Tomasz Hueckel and Hans Ziegler, in which the elastic moduli are altered by irreversible processes during loading. This complex behavior is explored for multi-directional loading probes that follow an initial monotonic loading. An advanced DEM model is used in the study, with non-convex non-spherical particles and two different contact models: a conventional linear-frictional model and an exact implementation of the Hertz-like Cattaneo-Mindlin model. Orthotropic true-triaxial probes were used in the study (i.e., no direct shear strain), with tiny strain increments of 2 ×10-6 . At the micro-scale, contact movements were monitored during small increments of loading and load-reversal, and results show that these movements are not reversed by a reversal of strain direction, and some contacts that were sliding during a loading increment continue to slide during reversal. The probes show that the coupled part of a strain increment, the difference between the recoverable (elastic) increment and its reversible part, must be considered when partitioning strain increments into elastic and plastic parts. Small increments of irreversible (and plastic) strain and contact slipping and frictional dissipation occur for all directions of loading, and an elastic domain, if it exists at all, is smaller than the strain increment used in the simulations.

40 CFR 60.2860 - What are the emission limitations for air curtain incinerators?

Code of Federal Regulations, 2014 CFR

2014-07-01

... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Air...

40 CFR 60.2765 - When must I submit my annual report?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2765...

40 CFR 60.2670 - What emission limitations must I meet and by when?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Emission...

40 CFR 60.2745 - Where and in what format must I keep my records?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and...

40 CFR 60.2670 - What emission limitations must I meet and by when?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Emission...

40 CFR 60.2810 - What is an air curtain incinerator?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Air Curtain Incinerators § 60.2810 What...

40 CFR 60.2765 - When must I submit my annual report?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2765...

40 CFR 60.2745 - Where and in what format must I keep my records?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and...

40 CFR 60.2690 - How do I conduct the initial and annual performance test?

Code of Federal Regulations, 2013 CFR

2013-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Performance Testing...

40 CFR 60.2705 - By what date must I conduct the initial performance test?

Code of Federal Regulations, 2013 CFR

2013-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Initial Compliance...

40 CFR 60.2705 - By what date must I conduct the initial performance test?

Code of Federal Regulations, 2014 CFR

2014-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Initial Compliance...

40 CFR 60.2715 - By what date must I conduct the annual performance test?

Code of Federal Regulations, 2013 CFR

2013-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Continuous...

40 CFR 60.2690 - How do I conduct the initial and annual performance test?

Code of Federal Regulations, 2014 CFR

2014-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Performance Testing...

40 CFR 60.2715 - By what date must I conduct the annual performance test?

Code of Federal Regulations, 2014 CFR

2014-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Continuous...

40 CFR 60.2865 - How must I monitor opacity for air curtain incinerators?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Air...

40 CFR 60.2780 - What must I include in the deviation report?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and... downtime associated with zero, span, and other routine calibration checks). (f) Whether each deviation...

Automated detection of pain from facial expressions: a rule-based approach using AAM

NASA Astrophysics Data System (ADS)

Chen, Zhanli; Ansari, Rashid; Wilkie, Diana J.

2012-02-01

In this paper, we examine the problem of using video analysis to assess pain, an important problem especially for critically ill, non-communicative patients, and people with dementia. We propose and evaluate an automated method to detect the presence of pain manifested in patient videos using a unique and large collection of cancer patient videos captured in patient homes. The method is based on detecting pain-related facial action units defined in the Facial Action Coding System (FACS) that is widely used for objective assessment in pain analysis. In our research, a person-specific Active Appearance Model (AAM) based on Project-Out Inverse Compositional Method is trained for each patient individually for the modeling purpose. A flexible representation of the shape model is used in a rule-based method that is better suited than the more commonly used classifier-based methods for application to the cancer patient videos in which pain-related facial actions occur infrequently and more subtly. The rule-based method relies on the feature points that provide facial action cues and is extracted from the shape vertices of AAM, which have a natural correspondence to face muscular movement. In this paper, we investigate the detection of a commonly used set of pain-related action units in both the upper and lower face. Our detection results show good agreement with the results obtained by three trained FACS coders who independently reviewed and scored the action units in the cancer patient videos.

76 FR 18038 - Airworthiness Directives; Airbus Model A340-200 and -300 Series Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... MCAI states: Two A340-300 aeroplanes experienced one single door opening of engine number (n[deg]) 3... the United States. Pursuant to our bilateral agreement with the State of Design Authority, we have... products of this type currently registered in the United States. However, this rule is necessary to ensure...

40 CFR 60.2665 - What if all the qualified operators are temporarily not accessible?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator... accessible and that you are resuming operation. Model Rule—Emission Limitations and Operating Limits ...

40 CFR 60.2665 - What if all the qualified operators are temporarily not accessible?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator... accessible and that you are resuming operation. Model Rule—Emission Limitations and Operating Limits ...

The value of atorvastatin over the product life cycle in the United States.

PubMed

Grabner, Michael; Johnson, Wallace; Abdulhalim, Abdulla M; Kuznik, Andreas; Mullins, C Daniel

2011-10-01

US health care reform mandates the reduction of wasteful health care spending while maintaining quality of care. Introducing new drugs into crowded therapeutic classes may be viewed as offering "me-too" (new drugs with a similar mechanism of action compared to existing drugs) drugs without incremental benefit. This article presents an analysis of the incremental costs and benefits of atorvastatin, a lipid-lowering agent. This analysis models the cost-effectiveness of atorvastatin over the product life cycle. The yearly cost-effectiveness of atorvastatin compared to simvastatin was modeled from 1997 to 2030 from the point of view of a US third-party payer. Estimates for incremental costs (in US $) and effects (in quality-adjusted life-years [QALYs]) for the primary and secondary prevention of cardiovascular events were taken from previously published literature and adjusted for changes in drug prices over time. Estimates of total statin use were derived using the National Health and Nutrition Examination Survey. Sensitivity analyses were conducted to examine variations in study parameters, including drug prices, indications, and discount rates. Assuming increasing statin use over time (with a mean of 1.07 million new users per year) and a 3% discount rate, the cumulative incremental cost-effectiveness ratio (ICER) of atorvastatin versus simvastatin ranged from cost-savings at release to a maximum of $45,066/QALY after 6 years of generic simvastatin use in 2012. Over the full modeled life cycle (1997-2030), the cumulative ICER of atorvastatin was $20,331/QALY. The incremental value of atorvastatin to US payers (after subtracting costs) was estimated at $44.57 to $194.78 billion, depending on willingness to pay. Findings from the sensitivity analyses were similar. A hypothetical situation in which atorvastatin did not exist was associated with a reduction in total expenditures but also a loss of QALYs gained. The cumulative ICER of atorvastatin varied across the product life cycle, increasing during the period between generic simvastatin entry and generic atorvastatin entry, and decreasing thereafter. Copyright © 2011 Elsevier HS Journals, Inc. All rights reserved.

Using decision modeling to determine pricing of new pharmaceuticals: the case of neurokinin-1 receptor antagonist antiemetics for cancer chemotherapy.

PubMed

Dranitsaris, George; Leung, Pauline

2004-01-01

Decision analysis is commonly used to perform economic evaluations of new pharmaceuticals. The outcomes of such studies are often reported as an incremental cost per quality-adjusted life year (QALY) gained with the new agent. Decision analysis can also be used in the context of estimating drug cost before market entry. The current study used neurokinin-1 (NK-1) receptor antagonists, a new class of antiemetics for cancer patients, as an example to illustrate the process using an incremental cost of dollars Can20,000 per QALY gained as the target threshold. A decision model was developed to simulate the control of acute and delayed emesis after cisplatin-based chemotherapy. The model compared standard therapy with granisetron and dexamethasone to the same protocol with the addition of an NK-1 before chemotherapy and continued twice daily for five days. The rates of complete emesis control were abstracted from a double-blind randomized trial. Costs of standard antiemetics and therapy for breakthrough vomiting were obtained from hospital sources. Utility estimates characterized as quality-adjusted emesis-free days were determined by interviewing twenty-five oncology nurses and pharmacists by using the Time Trade-Off technique. These data were then used to estimate the unit cost of the new antiemetic using a target threshold of dollars Can20,000 per QALY gained. A cost of dollars Can6.60 per NK-1 dose would generate an incremental cost of dollars Can20,000 per QALY. The sensitivity analysis on the unit cost identified a range from dollars Can4.80 to dollars Can10.00 per dose. For the recommended five days of therapy, the total cost should be dollars Can66.00 (dollars Can48.00-dollars Can100.00) for optimal economic efficiency relative to Canada's publicly funded health-care system. The use of decision modeling for estimating drug cost before product launch is a powerful technique to ensure value for money. Such information can be of value to both drug manufacturers and formulary committees, because it would facilitate negotiations for optimal pricing in a given jurisdiction.

Model based design introduction: modeling game controllers to microprocessor architectures

NASA Astrophysics Data System (ADS)

Jungwirth, Patrick; Badawy, Abdel-Hameed

2017-04-01

We present an introduction to model based design. Model based design is a visual representation, generally a block diagram, to model and incrementally develop a complex system. Model based design is a commonly used design methodology for digital signal processing, control systems, and embedded systems. Model based design's philosophy is: to solve a problem - a step at a time. The approach can be compared to a series of steps to converge to a solution. A block diagram simulation tool allows a design to be simulated with real world measurement data. For example, if an analog control system is being upgraded to a digital control system, the analog sensor input signals can be recorded. The digital control algorithm can be simulated with the real world sensor data. The output from the simulated digital control system can then be compared to the old analog based control system. Model based design can compared to Agile software develop. The Agile software development goal is to develop working software in incremental steps. Progress is measured in completed and tested code units. Progress is measured in model based design by completed and tested blocks. We present a concept for a video game controller and then use model based design to iterate the design towards a working system. We will also describe a model based design effort to develop an OS Friendly Microprocessor Architecture based on the RISC-V.

Exercise responses in patients with chronically high creatine kinase levels.

PubMed

Cooper, Christopher B; Dolezal, Brett A; Neufeld, Eric V; Shieh, Perry; Jenner, John R; Riley, Marshall

2017-08-01

Elevated serum creatine kinase (CK) is often taken to reflect muscle disease, but many individuals have elevated CK without a specific diagnosis. How elevated CK reflects muscle metabolism during exercise is not known. Participants (46 men, 48 women) underwent incremental exercise testing to assess aerobic performance, cardiovascular response, and ventilatory response. Serum lactate, ammonia, and CK were measured at rest, 4 minutes into exercise, and 2 minutes into recovery. High-CK and control subjects demonstrated similar aerobic capacities and cardiovascular responses to incremental exercise. Those with CK ≥ 300 U/L exhibited significantly higher lactate and ammonia levels after maximal exercise, together with increased ventilatory responses, whereas those with CK ≥200 U/L but ≤ 300 U/L did not. We recommend measurement of lactate and ammonia profiles during a maximal incremental exercise protocol to help identify patients who warrant muscle biopsy to rule out myopathy. Muscle Nerve 56: 264-270, 2017. © 2016 Wiley Periodicals, Inc.

5 CFR 3101.110 - Additional rules for United States Customs Service employees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Customs Service employees. 3101.110 Section 3101.110 Administrative Personnel DEPARTMENT OF THE TREASURY... rules for United States Customs Service employees. The following rules apply to the employees of the United States Customs Service and are in addition to §§ 3101.101 through 3101.104: (a) Prohibition on...

5 CFR 3101.110 - Additional rules for United States Customs Service employees.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Customs Service employees. 3101.110 Section 3101.110 Administrative Personnel DEPARTMENT OF THE TREASURY... rules for United States Customs Service employees. The following rules apply to the employees of the United States Customs Service and are in addition to §§ 3101.101 through 3101.104: (a) Prohibition on...

5 CFR 3101.110 - Additional rules for United States Customs Service employees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Customs Service employees. 3101.110 Section 3101.110 Administrative Personnel DEPARTMENT OF THE TREASURY... rules for United States Customs Service employees. The following rules apply to the employees of the United States Customs Service and are in addition to §§ 3101.101 through 3101.104: (a) Prohibition on...

5 CFR 3101.110 - Additional rules for United States Customs Service employees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Customs Service employees. 3101.110 Section 3101.110 Administrative Personnel DEPARTMENT OF THE TREASURY... rules for United States Customs Service employees. The following rules apply to the employees of the United States Customs Service and are in addition to §§ 3101.101 through 3101.104: (a) Prohibition on...

5 CFR 3101.110 - Additional rules for United States Customs Service employees.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Customs Service employees. 3101.110 Section 3101.110 Administrative Personnel DEPARTMENT OF THE TREASURY... rules for United States Customs Service employees. The following rules apply to the employees of the United States Customs Service and are in addition to §§ 3101.101 through 3101.104: (a) Prohibition on...

47 CFR 95.194 - (FRS Rule 4) FRS units.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false (FRS Rule 4) FRS units. 95.194 Section 95.194 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES Family Radio Service (FRS) General Provisions § 95.194 (FRS Rule 4) FRS units. (a) You may only...

77 FR 66481 - Hearings of the Judicial Conference Advisory Committee on Rules of Civil Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-05

... JUDICIAL CONFERENCE OF THE UNITED STATES Hearings of the Judicial Conference Advisory Committee on Rules of Civil Procedure AGENCY: Judicial Conference of the United States, Advisory Committee on Rules... Circle NE., Washington, DC 20544. FOR FURTHER INFORMATION CONTACT: Jonathan C. Rose, Chief Rules Officer...

78 FR 76177 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

... JUDICIAL CONFERENCE OF THE UNITED STATES Meeting of the Judicial Conference Committee on Rules of Practice and Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of..., Phoenix, Arizona 85003. FOR FURTHER INFORMATION CONTACT: Jonathan C. Rose, Secretary and Chief Rules...

77 FR 72885 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of Civil Procedure... Timberdell Road, Norman, OK 73019. FOR FURTHER INFORMATION CONTACT: Jonathan C. Rose, Secretary and Chief Rules Officer, Rules Committee Support Office, Administrative Office of the United States Courts...

Cross-State Air Pollution Rule Update Allowance Allocation Final Rule TSD

EPA Pesticide Factsheets

This Technical Support Document (TSD) provides information that supports EPA’s determination of unit-level allocations for existing and new units under the final Cross-State Air Pollution Rule Update.

Do Chinese Readers Follow the National Standard Rules for Word Segmentation during Reading?

PubMed Central

Liu, Ping-Ping; Li, Wei-Jun; Lin, Nan; Li, Xing-Shan

2013-01-01

We conducted a preliminary study to examine whether Chinese readers’ spontaneous word segmentation processing is consistent with the national standard rules of word segmentation based on the Contemporary Chinese language word segmentation specification for information processing (CCLWSSIP). Participants were asked to segment Chinese sentences into individual words according to their prior knowledge of words. The results showed that Chinese readers did not follow the segmentation rules of the CCLWSSIP, and their word segmentation processing was influenced by the syntactic categories of consecutive words. In many cases, the participants did not consider the auxiliary words, adverbs, adjectives, nouns, verbs, numerals and quantifiers as single word units. Generally, Chinese readers tended to combine function words with content words to form single word units, indicating they were inclined to chunk single words into large information units during word segmentation. Additionally, the “overextension of monosyllable words” hypothesis was tested and it might need to be corrected to some degree, implying that word length have an implicit influence on Chinese readers’ segmentation processing. Implications of these results for models of word recognition and eye movement control are discussed. PMID:23408981

Influence of light curing and sample thickness on microhardness of a composite resin

PubMed Central

Aguiar, Flávio HB; Andrade, Kelly RM; Leite Lima, Débora AN; Ambrosano, Gláucia MB; Lovadino, José R

2009-01-01

The aim of this in vitro study was to evaluate the influence of light-curing units and different sample thicknesses on the microhardness of a composite resin. Composite resin specimens were randomly prepared and assigned to nine experimental groups (n = 5): considering three light-curing units (conventional quartz tungsten halogen [QTH]: 550 mW/cm2 – 20 s; high irradiance QTH: 1160 mW/cm2 – 10 s; and light-emitting diode [LED]: 360 mW/cm2 – 40 s) and three sample thicknesses (0.5 mm, 1 mm, and 2 mm). All samples were polymerized with the light tip 8 mm away from the specimen. Knoop microhardness was then measured on the top and bottom surfaces of each sample. The top surfaces, with some exceptions, were almost similar; however, in relation to the bottom surfaces, statistical differences were found between curing units and thicknesses. In all experimental groups, the 0.5-mm-thick increments showed microhardness values statistically higher than those observed for 1- and -2-mm increments. The conventional and LED units showed higher hardness mean values and were statistically different from the high irradiance unit. In all experimental groups, microhardness mean values obtained for the top surface were higher than those observed for the bottom surface. In conclusion, higher levels of irradiance or thinner increments would help improve hybrid composite resin polymerization. PMID:23674901

Comparative study of adaptive controller using MIT rules and Lyapunov method for MPPT standalone PV systems

NASA Astrophysics Data System (ADS)

Tariba, N.; Bouknadel, A.; Haddou, A.; Ikken, N.; Omari, Hafsa El; Omari, Hamid El

2017-01-01

The Photovoltaic Generator have a nonlinear characteristic function relating the intensity at the voltage I = f (U) and depend on the variation of solar irradiation and temperature, In addition, its point of operation depends directly on the load that it supplies. To fix this drawback, and to extract the maximum power available to the terminal of the generator, an adaptation stage is introduced between the generator and the load to couple the two elements as perfectly as possible. The adaptation stage is associated with a command called MPPT MPPT (Maximum Power Point Tracker) whose is used to force the PVG to operate at the MPP (Maximum Power Point) under variation of climatic conditions and load variation. This paper presents a comparative study between the adaptive controller for PV Systems using MIT rules and Lyapunov method to regulate the PV voltage. The Incremental Conductance (IC) algorithm is used to extract the maximum power from the PVG by calculating the voltage Vref, and the adaptive controller is used to regulate and track quickly the PV voltage. The two methods of the adaptive controller will be compared to prove their performance by using the PSIM tools and experimental test, and the mathematical model of step-up with PVG model will be presented.

Modelling and Prediction of Spark-ignition Engine Power Performance Using Incremental Least Squares Support Vector Machines

NASA Astrophysics Data System (ADS)

Wong, Pak-kin; Vong, Chi-man; Wong, Hang-cheong; Li, Ke

2010-05-01

Modern automotive spark-ignition (SI) power performance usually refers to output power and torque, and they are significantly affected by the setup of control parameters in the engine management system (EMS). EMS calibration is done empirically through tests on the dynamometer (dyno) because no exact mathematical engine model is yet available. With an emerging nonlinear function estimation technique of Least squares support vector machines (LS-SVM), the approximate power performance model of a SI engine can be determined by training the sample data acquired from the dyno. A novel incremental algorithm based on typical LS-SVM is also proposed in this paper, so the power performance models built from the incremental LS-SVM can be updated whenever new training data arrives. With updating the models, the model accuracies can be continuously increased. The predicted results using the estimated models from the incremental LS-SVM are good agreement with the actual test results and with the almost same average accuracy of retraining the models from scratch, but the incremental algorithm can significantly shorten the model construction time when new training data arrives.

40 CFR 60.2675 - What operating limits must I meet and by when?

Code of Federal Regulations, 2014 CFR

2014-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Emission Limitations... electronic submission of the test report must also include the make and model of the PM CPMS instrument...

40 CFR 60.2800 - Can reporting dates be changed?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2800 Can... dates. See § 60.19(c) for procedures to seek approval to change your reporting date. Model Rule—Title V...

40 CFR 60.2800 - Can reporting dates be changed?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2800 Can... dates. See § 60.19(c) for procedures to seek approval to change your reporting date. Model Rule—Title V...

40 CFR 60.2675 - What operating limits must I meet and by when?

Code of Federal Regulations, 2013 CFR

2013-07-01

...) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Emission Limitations... electronic submission of the test report must also include the make and model of the PM CPMS instrument...

40 CFR 60.2620 - What is a waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Waste Management Plan § 60.2620 What is a...

40 CFR 60.2790 - Are there any other notifications or reports that I must submit?

Code of Federal Regulations, 2013 CFR

2013-07-01

... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule...

40 CFR 60.2790 - Are there any other notifications or reports that I must submit?

Code of Federal Regulations, 2014 CFR

2014-07-01

... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule...

40 CFR 60.2620 - What is a waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Waste Management Plan § 60.2620 What is a...

Implicit theories about intelligence and growth (personal best) goals: Exploring reciprocal relationships.

PubMed

Martin, Andrew J

2015-06-01

There has been increasing interest in growth approaches to students' academic development, including value-added models, modelling of academic trajectories, growth motivation orientations, growth mindsets, and growth goals. This study sought to investigate the relationships between implicit theories about intelligence (incremental and entity theories) and growth (personal best, PB) goals - with particular interest in the ordering of factors across time. The study focused on longitudinal data of 969 Australian high school students. The classic cross-lagged panel design (using structural equation modelling) was employed to shed light on the ordering of Time 1 growth goals, incremental theories, and entity theories relative to Time 2 (1 year later) growth goals, incremental theories, and entity theories. Findings showed that Time 1 growth goals predicted Time 2 incremental theories (positively) and entity theories (negatively); Time 1 entity and incremental theories negatively predicted Time 2 incremental and entity theories respectively; but, Time 1 incremental theories and entity theories did not predict growth goals at Time 2. This suggests that entity and incremental theories are negatively reciprocally related across time, but growth goals seem to be directionally salient over incremental and entity theories. Implications for promoting growth goals and growth mindsets are discussed. © 2014 The British Psychological Society.

A Low-Complexity Circuit for On-Sensor Concurrent A/D Conversion and Compression

NASA Technical Reports Server (NTRS)

Leon-Salas, Walter D.; Balkir, Sina; Sayood, Khalid; Schemm, Nathan; Hoffman, Michael W.

2007-01-01

A low-complexity circuit for on-sensor compression is presented. The proposed circuit achieves complexity savings by combining a single-slope analog-to-digital converter with a Golomb-Rice entropy encoder and by implementing a low-complexity adaptation rule. The adaptation rule monitors the output codewords and minimizes their length by incrementing or decrementing the value of the Golomb-Rice coding parameter k. Its hardware implementation is one order of magnitude lower than existing adaptive algorithms. The compression circuit has been fabricated using a 0.35 micrometers CMOS technology and occupies an area of 0.0918 mm2. Test measurements confirm the validity of the design

Estimating the cost-effectiveness of stroke units in France compared with conventional care.

PubMed

Launois, R; Giroud, M; Mégnigbêto, A C; Le Lay, K; Présenté, G; Mahagne, M H; Durand, I; Gaudin, A F

2004-03-01

The incidence of stroke in France is estimated at between 120 000 and 150 000 cases per year. This modeling study assessed the clinical and economic benefits of establishing specialized stroke units compared with conventional care. Data from the Dijon stroke registry were used to determine healthcare trajectories according to the degree of autonomy and organization of patient care. The relative risks of death or institutionalization or death or dependence after passage through a stroke unit were compared with conventional care. These risks were then inserted with the costing data into a Markov model to estimate the cost-effectiveness of stroke units. Patients cared for in a stroke unit survive more trimesters without sequelae in the 5 years after hospitalization than those cared for conventionally (11.6 versus 8.28 trimesters). The mean cost per patient at 5 years was estimated at 30 983 for conventional care and 34 638 in a stroke unit. An incremental cost-effectiveness ratio for stroke units of 1359 per year of life gained without disability was estimated. The cost-effectiveness ratio for stroke units is much lower than the threshold (53 400 ) of acceptability recognized by the international scientific community. This finding justifies organizational changes in the management of stroke patients and the establishment of stroke units in France.

75 FR 41927 - Sentencing Guidelines for United States Courts

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-19

... UNITED STATES SENTENCING COMMISSION Sentencing Guidelines for United States Courts AGENCY: United... operation of the Federal sentencing guidelines, and in accordance with Rule 5.2 of its Rules of Practice and... branch of the United States Government. The Commission promulgates sentencing guidelines and policy...

76 FR 45007 - Sentencing Guidelines for United States Courts

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-27

... UNITED STATES SENTENCING COMMISSION Sentencing Guidelines for United States Courts AGENCY: United... operation of the Federal sentencing guidelines, and in accordance with Rule 5.2 of its Rules of Practice and... branch of the United States Government. The Commission promulgates sentencing guidelines and policy...

77 FR 72884 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... JUDICIAL CONFERENCE OF THE UNITED STATES Meeting of the Judicial Conference Committee on Rules of Practice and Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of... but not participation. DATES: April 2-3, 2013. Time: 8:30 a.m. to 5:00 p.m. ADDRESSES: United States...

77 FR 59241 - Notice of Effective Date of Modifications to Certain Textile and Apparel Rules of Origin of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-26

... Rules of Origin of the Dominican Republic-Central America- United States Free Trade Agreement AGENCY... Certain Textile and Apparel Rules of Origin of the Dominican Republic-Central America- United States Free...- Central America-United States Free Trade Agreement Implementation Act (the ``CAFTA-DR Act'') approved the...

75 FR 1101 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-08

... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-61261; File No. SR-BX-2009-086] Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness of Proposed Rule Change Relating to the Minimum Trading Increments on the Boston Options Exchange Facility December 30, 2009. Pursuant to Section 19(b)(1) of the...

76 FR 23849 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-28

... Change To Permit the Listing of Series With $0.50 and $1 Strike Price Increments on Certain Options Used... price is between $75 and $150 for option series used to calculate volatility indexes. The text of the... option series used to calculate volatility indexes. The proposal is based on a recently approved rule...

78 FR 56253 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-12

... Rule Change Relating to $0.50 and $1 Strike Price Intervals for Classes in the Short Term Option Series... options classes that trade in one dollar increments and are in the Short Term Option Series Program... business day, series of options on no more than thirty option classes that expire on each of the next five...

78 FR 32496 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-30

... notice to solicit comments on the proposed rule change from interested persons. \\1\\ 15 U.S.C. 78s(b)(1... there is a reasonable lowest minimum increment for bids and offers that makes it simple to monitor and... national market system, and, in general, to protect investors and the public interest. Additionally, the...

78 FR 37854 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-24

... To Extend the Penny Pilot Program and Amend Rule 7050 June 18, 2013. Pursuant to Section 19(b)(1) of... that permits certain classes to be quoted in penny increments (``Penny Pilot Program'') and to remove... extend the effective time period of the Penny Pilot Program that is currently scheduled to expire on June...

78 FR 974 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-07

... Change Relating to the Exchange Penny Pilot Program December 31, 2012. Pursuant to Section 19(b)(1) \\1... Penny Pilot Program. The text of the proposed rule change is provided below. [(additions are italicized... increments for bids and offers for all series of the option classes participating in the Penny Pilot Program...

75 FR 12320 - Self-Regulatory Organization; The Options Clearing Corporation; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-15

... rule change will amend the definition of ``adjustment increment'' applicable to stock futures. II. Self...). Daily settlement prices and trade prices would continue to be expressed in pennies on a per-contract... settlement price the following day is $50.05, a mark-to-market of $50.05-$49.875 = $0.1750, or $17.50 per...

77 FR 72885 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... JUDICIAL CONFERENCE OF THE UNITED STATES Meeting of the Judicial Conference Committee on Rules of Practice and Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of..., Coral Gables, FL 33146. FOR FURTHER INFORMATION CONTACT: Jonathan C. Rose, Secretary and Chief Rules...

33 CFR 83.01 - Application (Rule 1).

Code of Federal Regulations, 2010 CFR

2010-07-01

... waters of the Great Lakes. These Rules apply to all vessels upon the inland waters of the United States, and to vessels of the United States on the Canadian waters of the Great Lakes to the extent that there... rules made by an appropriate authority within the meaning of Rule 1(b) of the International Regulations...

33 CFR 83.01 - Application (Rule 1).

Code of Federal Regulations, 2013 CFR

2013-07-01

... waters of the Great Lakes. These Rules apply to all vessels upon the inland waters of the United States, and to vessels of the United States on the Canadian waters of the Great Lakes to the extent that there... rules made by an appropriate authority within the meaning of Rule 1(b) of the International Regulations...

33 CFR 83.01 - Application (Rule 1).

Code of Federal Regulations, 2014 CFR

2014-07-01

... waters of the Great Lakes. These Rules apply to all vessels upon the inland waters of the United States, and to vessels of the United States on the Canadian waters of the Great Lakes to the extent that there... rules made by an appropriate authority within the meaning of Rule 1(b) of the International Regulations...

33 CFR 83.01 - Application (Rule 1).

Code of Federal Regulations, 2012 CFR

2012-07-01

... waters of the Great Lakes. These Rules apply to all vessels upon the inland waters of the United States, and to vessels of the United States on the Canadian waters of the Great Lakes to the extent that there... rules made by an appropriate authority within the meaning of Rule 1(b) of the International Regulations...

33 CFR 83.01 - Application (Rule 1).

Code of Federal Regulations, 2011 CFR

2011-07-01

... waters of the Great Lakes. These Rules apply to all vessels upon the inland waters of the United States, and to vessels of the United States on the Canadian waters of the Great Lakes to the extent that there... rules made by an appropriate authority within the meaning of Rule 1(b) of the International Regulations...

Weak percolation on multiplex networks

NASA Astrophysics Data System (ADS)

Baxter, Gareth J.; Dorogovtsev, Sergey N.; Mendes, José F. F.; Cellai, Davide

2014-04-01

Bootstrap percolation is a simple but nontrivial model. It has applications in many areas of science and has been explored on random networks for several decades. In single-layer (simplex) networks, it has been recently observed that bootstrap percolation, which is defined as an incremental process, can be seen as the opposite of pruning percolation, where nodes are removed according to a connectivity rule. Here we propose models of both bootstrap and pruning percolation for multiplex networks. We collectively refer to these two models with the concept of "weak" percolation, to distinguish them from the somewhat classical concept of ordinary ("strong") percolation. While the two models coincide in simplex networks, we show that they decouple when considering multiplexes, giving rise to a wealth of critical phenomena. Our bootstrap model constitutes the simplest example of a contagion process on a multiplex network and has potential applications in critical infrastructure recovery and information security. Moreover, we show that our pruning percolation model may provide a way to diagnose missing layers in a multiplex network. Finally, our analytical approach allows us to calculate critical behavior and characterize critical clusters.

39 CFR 3050.23 - Documentation supporting incremental cost estimates in the Postal Service's section 3652 report.

Code of Federal Regulations, 2010 CFR

2010-07-01

... incremental cost model shall be reported. ... 39 Postal Service 1 2010-07-01 2010-07-01 false Documentation supporting incremental cost... REGULATORY COMMISSION PERSONNEL PERIODIC REPORTING § 3050.23 Documentation supporting incremental cost...

[Individual tree diameter increment model for natural Betula platyphylla forests based on meteorological factors].

PubMed

Zhang, Hai Ping; Li, Feng Ri; Dong, Li Hu; Liu, Qiang

2017-06-18

Based on the 212 re-measured permanent plots for natural Betula platyphylla fore-sts in Daxing'an Mountains and Xiaoxing'an Mountains and 30 meteorological stations data, an individual tree growth model based on meteorological factors was constructed. The differences of stand and meteorological factors between Daxing'an Mountains and Xiaoxing'an Mountains were analyzed and the diameter increment model including the regional effects was developed by dummy variable approach. The results showed that the minimum temperature (T g min ) and mean precipitation (P g m ) in growing season were the main meteorological factors which affected the diameter increment in the two study areas. T g min and P g m were positively correlated with the diameter increment, but the influence strength of T g min was obviously different between the two research areas. The adjusted coefficient of determination (R a 2 ) of the diameter increment model with meteorological factors was 0.56 and had an 11% increase compared to the one without meteorological factors. It was concluded that meteorological factors could well explain the diameter increment of B. platyphylla. R a 2 of the model with regional effects was 0.59, and increased by 18% compared to the one without regional effects, and effectively solved the incompatible problem of parameters between the two research areas. The validation results showed that the individual tree diameter growth model with regional effect had the best prediction accuracy in estimating the diameter increment of B. platyphylla. The mean error, mean absolute error, mean error percent and mean prediction error percent were 0.0086, 0.4476, 5.8% and 20.0%, respectively. Overall, dummy variable model of individual tree diameter increment based on meteorological factors could well describe the diameter increment process of natural B. platyphylla in Daxing'an Mountains and Xiaoxing'an Mountains.

46 CFR 174.080 - Flooding on self-elevating and surface type units.

Code of Federal Regulations, 2010 CFR

2010-10-01

... STABILITY SPECIAL RULES PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Mobile Offshore Drilling Units § 174.080 Flooding on self-elevating and surface type units. (a) On a surface type unit or...

46 CFR 174.080 - Flooding on self-elevating and surface type units.

Code of Federal Regulations, 2013 CFR

2013-10-01

... STABILITY SPECIAL RULES PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Mobile Offshore Drilling Units § 174.080 Flooding on self-elevating and surface type units. (a) On a surface type unit or...

International Space Station Increment-4/5 Microgravity Environment Summary Report

NASA Technical Reports Server (NTRS)

Jules, Kenol; Hrovat, Kenneth; Kelly, Eric; McPherson, Kevin; Reckart, Timothy

2003-01-01

This summary report presents the results of some of the processed acceleration data measured aboard the International Space Station during the period of December 2001 to December 2002. Unlike the past two ISS Increment reports, which were increment specific, this summary report covers two increments: Increments 4 and 5, hereafter referred to as Increment-4/5. Two accelerometer systems were used to measure the acceleration levels for the activities that took place during Increment-4/5. Due to time constraint and lack of precise timeline information regarding some payload operations and station activities, not a11 of the activities were analyzed for this report. The National Aeronautics and Space Administration sponsors the Microgravity Acceleration Measurement System and the Space Acceleration Microgravity System to support microgravity science experiments which require microgravity acceleration measurements. On April 19, 2001, both the Microgravity Acceleration Measurement System and the Space Acceleration Measurement System units were launched on STS-100 from the Kennedy Space Center for installation on the International Space Station. The Microgravity Acceleration Measurement System supports science experiments requiring quasi-steady acceleration measurements, while the Space Acceleration Measurement System unit supports experiments requiring vibratory acceleration measurement. The International Space Station Increment-4/5 reduced gravity environment analysis presented in this report uses acceleration data collected by both sets of accelerometer systems: The Microgravity Acceleration Measurement System, which consists of two sensors: the low-frequency Orbital Acceleration Research Experiment Sensor Subsystem and the higher frequency High Resolution Accelerometer Package. The low frequency sensor measures up to 1 Hz, but is routinely trimmean filtered to yield much lower frequency acceleration data up to 0.01 Hz. This filtered data can be mapped to arbitrary locations for characterizing the quasi-steady environment for payloads and the vehicle. The high frequency sensor is used to characterize the vibratory environment up to 100 Hz at a single measurement location. The Space Acceleration Measurement System, which deploys high frequency sensors, measures vibratory acceleration data in the range of 0.01 to 400 Hz at multiple measurement locations. This summary report presents analysis of some selected quasi-steady and vibratory activities measured by these accelerometers during Increment- 4/5 from December 2001 to December 2002.

Analysis of real-world health care costs among immunocompetent patients aged 50 years or older with herpes zoster in the United States.

PubMed

Meyers, Juliana L; Madhwani, Shweta; Rausch, Debora; Candrilli, Sean D; Krishnarajah, Girishanthy; Yan, Songkai

2017-08-03

Few peer-reviewed publications present real-world United States (US) data describing resource utilization and costs associated with herpes zoster (HZ) and postherpetic neuralgia (PHN). The primary objective of this analysis (GSK study identifier: HO-14-14270) was to assess direct costs associated with HZ and PHN in the US using a retrospective managed care insurance claims database. Patients ≥ 50 y at HZ diagnosis were selected. Patients were excluded if they were immunocompromised before diagnosis or received an HZ vaccine at any time. A subsample of patients with PHN was identified. Each patient with HZ was matched to ≤ 4 controls without HZ based on age, sex, and health plan enrollment. Incremental differences in mean HZ-related costs ("incremental costs") were assessed overall and stratified by age. Multivariable regression models controlled for the effect of demographic characteristics, prediagnosis costs, and comorbidity burden on costs using a recycled predictions approach. Overall, 142,519 patients with HZ (9,470 patients [6.6%] had PHN) and 357,907 matched controls without HZ were identified. Resource utilization was greater among patients with HZ than controls. After adjusting for demographic and clinical characteristics, annual incremental health care costs for HZ patients vs. controls were $1,210 for patients aged 50-59 years, $1,629 for those 60-64 years, $1,876 for those 65-69 years, $2,643 for those 70-79 years, and $3,804 for those 80+ years; adjusted annual incremental costs among PHN patients vs. controls were $4,670 for patients 50-59 years, $6,133 for those 60-64 years, $6,451 for those 65-69 years, $8,548 for those 70-79 years, and $11,147 for those 80+ years. HZ is associated with a significant cost burden, which increases with advancing patient age. Vaccination may reduce costs associated with HZ through case avoidance.

78 FR 29618 - Rules of Adjudication and Enforcement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-21

... INTERNATIONAL TRADE COMMISSION 19 CFR Part 210 Rules of Adjudication and Enforcement AGENCY: International Trade Commission. ACTION: Final rule. SUMMARY: The United States International Trade Commission... the General Counsel, United States International Trade Commission. Hearing-impaired individuals are...

Per tree estimates with n-tree distance sampling: an application to increment core data

Treesearch

Thomas B. Lynch; Robert F. Wittwer

2002-01-01

Per tree estimates using the n trees nearest a point can be obtained by using a ratio of per unit area estimates from n-tree distance sampling. This ratio was used to estimate average age by d.b.h. classes for cottonwood trees (Populus deltoides Bartr. ex Marsh.) on the Cimarron National Grassland. Increment...

Motor Controller System For Large Dynamic Range of Motor Operation

NASA Technical Reports Server (NTRS)

Howard, David E. (Inventor); Alhorn, Dean C. (Inventor); Smith, Dennis A. (Inventor); Dutton, Kenneth R. (Inventor); Paulson, Mitchell Scott (Inventor)

2006-01-01

A motor controller system uses a rotary sensor with a plurality of signal conditioning units, coupled to the rotary sensor. Each of these units, which is associated with a particular range of motor output shaft rotation rates, generate a feedback signal indicative of the position of the motor s output shaft. A controller (i) converts a selected motor output shaft rotation rate to a corresponding incremental amount of rotational movement for a selected fixed time period, (ii) selects, at periodic completions of the selected fixed time period, the feedback signal from one of the signal conditioning units for which the particular range of motor output shaft rotation rates associated therewith encompasses the selected motor output shaft rotation rate, and (iii) generates a motor drive signal based on a difference between the incremental amount of rotational movement and the feedback signal from the selected one of the signal conditioning Units.

77 FR 31069 - Sentencing Guidelines for United States Courts

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-24

... SENTENCING COMMISSION Sentencing Guidelines for United States Courts AGENCY: United States... federal sentencing guidelines, and in accordance with Rule 5.2 of its Rules of Practice and Procedure, the... the judicial branch of the United States Government. The Commission promulgates sentencing guidelines...

Intelligent fuzzy controller for event-driven real time systems

NASA Technical Reports Server (NTRS)

Grantner, Janos; Patyra, Marek; Stachowicz, Marian S.

1992-01-01

Most of the known linguistic models are essentially static, that is, time is not a parameter in describing the behavior of the object's model. In this paper we show a model for synchronous finite state machines based on fuzzy logic. Such finite state machines can be used to build both event-driven, time-varying, rule-based systems and the control unit section of a fuzzy logic computer. The architecture of a pipelined intelligent fuzzy controller is presented, and the linguistic model is represented by an overall fuzzy relation stored in a single rule memory. A VLSI integrated circuit implementation of the fuzzy controller is suggested. At a clock rate of 30 MHz, the controller can perform 3 MFLIPS on multi-dimensional fuzzy data.

A new security model for collaborative environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agarwal, Deborah; Lorch, Markus; Thompson, Mary

Prevalent authentication and authorization models for distributed systems provide for the protection of computer systems and resources from unauthorized use. The rules and policies that drive the access decisions in such systems are typically configured up front and require trust establishment before the systems can be used. This approach does not work well for computer software that moderates human-to-human interaction. This work proposes a new model for trust establishment and management in computer systems supporting collaborative work. The model supports the dynamic addition of new users to a collaboration with very little initial trust placed into their identity and supportsmore » the incremental building of trust relationships through endorsements from established collaborators. It also recognizes the strength of a users authentication when making trust decisions. By mimicking the way humans build trust naturally the model can support a wide variety of usage scenarios. Its particular strength lies in the support for ad-hoc and dynamic collaborations and the ubiquitous access to a Computer Supported Collaboration Workspace (CSCW) system from locations with varying levels of trust and security.« less

40 CFR 60.2994 - Are air curtain incinerators regulated under this subpart?

Code of Federal Regulations, 2010 CFR

2010-07-01

... and Compliance Times for Other Solid Waste Incineration Units That Commenced Construction On or Before... percent wood waste. (2) 100 percent clean lumber. (3) 100 percent yard waste. (4) 100 percent mixture of only wood waste, clean lumber, and/or yard waste. Model Rule—Use of Model Rule ...

Learning temporal rules to forecast instability in continuously monitored patients

PubMed Central

Dubrawski, Artur; Wang, Donghan; Hravnak, Marilyn; Clermont, Gilles; Pinsky, Michael R

2017-01-01

Inductive machine learning, and in particular extraction of association rules from data, has been successfully used in multiple application domains, such as market basket analysis, disease prognosis, fraud detection, and protein sequencing. The appeal of rule extraction techniques stems from their ability to handle intricate problems yet produce models based on rules that can be comprehended by humans, and are therefore more transparent. Human comprehension is a factor that may improve adoption and use of data-driven decision support systems clinically via face validity. In this work, we explore whether we can reliably and informatively forecast cardiorespiratory instability (CRI) in step-down unit (SDU) patients utilizing data from continuous monitoring of physiologic vital sign (VS) measurements. We use a temporal association rule extraction technique in conjunction with a rule fusion protocol to learn how to forecast CRI in continuously monitored patients. We detail our approach and present and discuss encouraging empirical results obtained using continuous multivariate VS data from the bedside monitors of 297 SDU patients spanning 29 346 hours (3.35 patient-years) of observation. We present example rules that have been learned from data to illustrate potential benefits of comprehensibility of the extracted models, and we analyze the empirical utility of each VS as a potential leading indicator of an impending CRI event. PMID:27274020

Modeling the economic impact of linezolid versus vancomycin in confirmed nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.

PubMed

Patel, Dipen A; Shorr, Andrew F; Chastre, Jean; Niederman, Michael; Simor, Andrew; Stephens, Jennifer M; Charbonneau, Claudie; Gao, Xin; Nathwani, Dilip

2014-07-22

We compared the economic impacts of linezolid and vancomycin for the treatment of hospitalized patients with methicillin-resistant Staphylococcus aureus (MRSA)-confirmed nosocomial pneumonia. We used a 4-week decision tree model incorporating published data and expert opinion on clinical parameters, resource use and costs (in 2012 US dollars), such as efficacy, mortality, serious adverse events, treatment duration and length of hospital stay. The results presented are from a US payer perspective. The base case first-line treatment duration for patients with MRSA-confirmed nosocomial pneumonia was 10 days. Clinical treatment success (used for the cost-effectiveness ratio) and failure due to lack of efficacy, serious adverse events or mortality were possible clinical outcomes that could impact costs. Cost of treatment and incremental cost-effectiveness per successfully treated patient were calculated for linezolid versus vancomycin. Univariate (one-way) and probabilistic sensitivity analyses were conducted. The model allowed us to calculate the total base case inpatient costs as $46,168 (linezolid) and $46,992 (vancomycin). The incremental cost-effectiveness ratio favored linezolid (versus vancomycin), with lower costs ($824 less) and greater efficacy (+2.7% absolute difference in the proportion of patients successfully treated for MRSA nosocomial pneumonia). Approximately 80% of the total treatment costs were attributed to hospital stay (primarily in the intensive care unit). The results of our probabilistic sensitivity analysis indicated that linezolid is the cost-effective alternative under varying willingness to pay thresholds. These model results show that linezolid has a favorable incremental cost-effectiveness ratio compared to vancomycin for MRSA-confirmed nosocomial pneumonia, largely attributable to the higher clinical trial response rate of patients treated with linezolid. The higher drug acquisition cost of linezolid was offset by lower treatment failure-related costs and fewer days of hospitalization.

An advanced artificial intelligence tool for menu design.

PubMed

Khan, Abdus Salam; Hoffmann, Achim

2003-01-01

The computer-assisted menu design still remains a difficult task. Usually knowledge that aids in menu design by a computer is hard-coded and because of that a computerised menu planner cannot handle the menu design problem for an unanticipated client. To address this problem we developed a menu design tool, MIKAS (menu construction using incremental knowledge acquisition system), an artificial intelligence system that allows the incremental development of a knowledge-base for menu design. We allow an incremental knowledge acquisition process in which the expert is only required to provide hints to the system in the context of actual problem instances during menu design using menus stored in a so-called Case Base. Our system incorporates Case-Based Reasoning (CBR), an Artificial Intelligence (AI) technique developed to mimic human problem solving behaviour. Ripple Down Rules (RDR) are a proven technique for the acquisition of classification knowledge from expert directly while they are using the system, which complement CBR in a very fruitful way. This combination allows the incremental improvement of the menu design system while it is already in routine use. We believe MIKAS allows better dietary practice by leveraging a dietitian's skills and expertise. As such MIKAS has the potential to be helpful for any institution where dietary advice is practised.

Cost-effectiveness acceptability curves revisited.

PubMed

Al, Maiwenn J

2013-02-01

Since the introduction of the cost-effectiveness acceptability curve (CEAC) in 1994, its use as a method to describe uncertainty around incremental cost-effectiveness ratios (ICERs) has steadily increased. In this paper, first the construction and interpretation of the CEAC is explained, both in the context of modelling studies and in the context of cost-effectiveness (CE) studies alongside clinical trials. Additionally, this paper reviews the advantages and limitations of the CEAC. Many of the perceived limitations can be attributed to the practice of interpreting the CEAC as a decision rule while it was not developed as such. It is argued that the CEAC is still a useful tool in describing and quantifying uncertainty around the ICER, especially in combination with other tools such as plots on the CE plane and value-of-information analysis.

40 CFR 60.2700 - How do I demonstrate initial compliance with the amended emission limitations and establish the...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF... Solid Waste Incineration Units Model Rule-Initial Compliance Requirements § 60.2700 How do I demonstrate...

40 CFR 60.2700 - How do I demonstrate initial compliance with the amended emission limitations and establish the...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF... Solid Waste Incineration Units Model Rule-Initial Compliance Requirements § 60.2700 How do I demonstrate...

40 CFR 60.1880 - When must I submit the annual report?

Code of Federal Regulations, 2010 CFR

2010-07-01

... of each year that follows the calendar year in which you collected the data. If you have an operating... Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule...

Awareness and use of the Ottawa ankle and knee rules in 5 countries: can publication alone be enough to change practice?

PubMed

Graham, I D; Stiell, I G; Laupacis, A; McAuley, L; Howell, M; Clancy, M; Durieux, P; Simon, N; Emparanza, J I; Aginaga, J R; O'connor, A; Wells, G

2001-03-01

We evaluate the international diffusion of the Ottawa Ankle and Knee Rules and determine emergency physicians' attitudes toward clinical decision rules in general. We conducted a cross-sectional, self-administered mail survey of random samples of 500 members each of the American College of Emergency Physicians, Canadian Association of Emergency Physicians, British Association for Accident and Emergency Medicine, Spanish Society for Emergency Medicine, and all members (n=1,350) of the French Speaking Society of Emergency Physicians, France. Main outcome measures were awareness of the Ottawa Ankle and Knee Rules, reported use of these rules, and attitudes toward clinical decision rules in general. A total of 1,769 (57%) emergency physicians responded, with country-specific response rates between 49% (United States and France) and 79% (Canada). More than 69% of physicians in all countries, except Spain, were aware of the Ottawa Ankle Rules. Use of the Ottawa Ankle Rules differed by country with more than 70% of all responding Canadian and United Kingdom physicians reporting frequent use of the rules compared with fewer than one third of US, French, and Spanish physicians. The Ottawa Knee Rule was less well known and less used by physicians in all countries. Most physicians in all countries viewed decision rules as intended to improve the quality of health care (>78%), a convenient source of advice (>67%), and good educational tools (>61%). Of all physicians, those from the United States held the least positive attitudes toward decision rules. This constitutes the largest international survey of emergency physicians' attitudes toward and use of clinical decision rules. Striking differences were apparent among countries with regard to knowledge and use of decision rules. Despite similar awareness in the United States, Canada, and the United Kingdom, US physicians appeared much less likely to use the Ottawa Ankle Rules. Future research should investigate factors leading to differences in rates of diffusion among countries and address strategies to enhance dissemination and implementation of such rules in the emergency department.

78 FR 62838 - Self-Regulatory Organizations; Topaz Exchange, LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... SPDR S&P 500 Exchange Traded Fund (``SPY'') and the iShares Russell 2000 Index Fund (``IWM''), is $0.01... $3 per contract or greater. QQQQ, SPY and IWM are traded in $0.01 increments for all options series... Securities Exchange Act of 1934 (the ``Act''),\\1\\ and Rule 19b-4 thereunder,\\2\\ notice is hereby given that...

76 FR 32385 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-06

... and Rule 1038 do not apply to orders placed in the cabinet. Cabinet transactions are not reported on... limited to options classes traded in $0.05 or $0.10 standard increments. The $1 cabinet trading procedures... Section 6 of the Act,\\9\\ in general, and with Section 6(b)(5) of the Act,\\10\\ in particular, in that the...

Evaluation of a Stratified National Breast Screening Program in the United Kingdom: An Early Model-Based Cost-Effectiveness Analysis.

PubMed

Gray, Ewan; Donten, Anna; Karssemeijer, Nico; van Gils, Carla; Evans, D Gareth; Astley, Sue; Payne, Katherine

2017-09-01

To identify the incremental costs and consequences of stratified national breast screening programs (stratified NBSPs) and drivers of relative cost-effectiveness. A decision-analytic model (discrete event simulation) was conceptualized to represent four stratified NBSPs (risk 1, risk 2, masking [supplemental screening for women with higher breast density], and masking and risk 1) compared with the current UK NBSP and no screening. The model assumed a lifetime horizon, the health service perspective to identify costs (£, 2015), and measured consequences in quality-adjusted life-years (QALYs). Multiple data sources were used: systematic reviews of effectiveness and utility, published studies reporting costs, and cohort studies embedded in existing NBSPs. Model parameter uncertainty was assessed using probabilistic sensitivity analysis and one-way sensitivity analysis. The base-case analysis, supported by probabilistic sensitivity analysis, suggested that the risk stratified NBSPs (risk 1 and risk-2) were relatively cost-effective when compared with the current UK NBSP, with incremental cost-effectiveness ratios of £16,689 per QALY and £23,924 per QALY, respectively. Stratified NBSP including masking approaches (supplemental screening for women with higher breast density) was not a cost-effective alternative, with incremental cost-effectiveness ratios of £212,947 per QALY (masking) and £75,254 per QALY (risk 1 and masking). When compared with no screening, all stratified NBSPs could be considered cost-effective. Key drivers of cost-effectiveness were discount rate, natural history model parameters, mammographic sensitivity, and biopsy rates for recalled cases. A key assumption was that the risk model used in the stratification process was perfectly calibrated to the population. This early model-based cost-effectiveness analysis provides indicative evidence for decision makers to understand the key drivers of costs and QALYs for exemplar stratified NBSP. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Antihypertensive drugs: a perspective on pharmaceutical price erosion and its impact on cost-effectiveness.

PubMed

Refoios Camejo, Rodrigo; McGrath, Clare; Herings, Ron; Meerding, Willem-Jan; Rutten, Frans

2012-01-01

When comparators' prices decrease due to market competition and loss of exclusivity, the incremental clinical effectiveness required for a new technology to be cost-effective is expected to increase; and/or the minimum price at which it will be funded will tend to decrease. This may be, however, either unattainable physiologically or financially unviable for drug development. The objective of this study is to provide an empirical basis for this discussion by estimating the potential for price decreases to impact on the cost-effectiveness of new therapies in hypertension. Cost-effectiveness at launch was estimated for all antihypertensive drugs launched between 1998 and 2008 in the United Kingdom using hypothetical degrees of incremental clinical effectiveness within the methodologic framework applied by the UK National Institute for Health and Clinical Excellence. Incremental cost-effectiveness ratios were computed and compared with funding thresholds. In addition, the levels of incremental clinical effectiveness required to achieve specific cost-effectiveness thresholds at given prices were estimated. Significant price decreases were observed for existing drugs. This was shown to markedly affect cost-effectiveness of technologies entering the market. The required incremental clinical effectiveness was in many cases greater than physiologically possible so, as a consequence, a number of products might not be available today if current methods of economic appraisal had been applied. We conclude that the definition of cost-effectiveness thresholds is fundamental in promoting efficient innovation. Our findings demonstrate that comparator price attrition has the potential to put pressure in the pharmaceutical research model and presents a challenge to new therapies being accepted for funding. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Modeling the effects of changes in New Source Review on national SO{sub 2} and NOx emissions from electricity-generating units

DOE Office of Scientific and Technical Information (OSTI.GOV)

David A. Evans; Benjamin F. Hobbs; Craig Oren

2007-03-15

The Clean Air Act establishes New Source Review (NSR) programs that apply to the construction or modification of major stationary emissions sources. In 2002 and 2003, the U.S. Environmental Protection Agency revised its rules to narrow the applicability of NSR to facility renovations. Congress then mandated a National Research Council study of the effects of the rules. An electricity-sector model - the Integrated Planning Model (IPM) - was used to explore the possible effects of the equipment replacement provision (ERP), the principal NSR change that was to affect the power-generation industry. The studies focused in particular on coal-fired electricity generatingmore » units, EGUs, for two reasons. First, coal-fired EGUs are important contributors of these pollutants, accounting for approximately 70 and 20% of nations SO{sub 2} and NOx emissions in 2004, respectively. Second, the shares of total capacity of large coal-fired EGUs that lack flue-gas desulfurization to control SO{sub 2} and selective catalytic reduction to reduce NOx emissions are 62 and 63% respectively. Although the analysis cannot predict effects on local emissions, assuming that the Clean Air Interstate Rule (CAIR) is implemented, we find that stringent enforcement of the previous NSR rules would likely lead to no or limited decreases in national emissions compared to policies such as ERP. Our results indicate that tighter emissions caps could achieve further decreases in national emissions more cost-effectively than NSR programs. 15 refs., 3 figs., 1 tab.« less

40 CFR 62.15090 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2013 CFR

2013-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 62.15090 Section 62.15090... Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Compliance Schedule and Increments of Progress § 62.15090 What must I do if I close my municipal waste combustion unit and then restart...

40 CFR 62.15090 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2010 CFR

2010-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 62.15090 Section 62.15090... Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Compliance Schedule and Increments of Progress § 62.15090 What must I do if I close my municipal waste combustion unit and then restart...

40 CFR 62.15090 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2014 CFR

2014-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 62.15090 Section 62.15090... Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Compliance Schedule and Increments of Progress § 62.15090 What must I do if I close my municipal waste combustion unit and then restart...

40 CFR 62.15090 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2012 CFR

2012-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 62.15090 Section 62.15090... Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Compliance Schedule and Increments of Progress § 62.15090 What must I do if I close my municipal waste combustion unit and then restart...

40 CFR 62.15090 - What must I do if I close my municipal waste combustion unit and then restart my municipal waste...

Code of Federal Regulations, 2011 CFR

2011-07-01

... waste combustion unit and then restart my municipal waste combustion unit? 62.15090 Section 62.15090... Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Compliance Schedule and Increments of Progress § 62.15090 What must I do if I close my municipal waste combustion unit and then restart...

Comparative economic evaluation of data from the ACRIN National CT Colonography Trial with three cancer intervention and surveillance modeling network microsimulations.

PubMed

Vanness, David J; Knudsen, Amy B; Lansdorp-Vogelaar, Iris; Rutter, Carolyn M; Gareen, Ilana F; Herman, Benjamin A; Kuntz, Karen M; Zauber, Ann G; van Ballegooijen, Marjolein; Feuer, Eric J; Chen, Mei-Hsiu; Johnson, C Daniel

2011-11-01

To estimate the cost-effectiveness of computed tomographic (CT) colonography for colorectal cancer (CRC) screening in average-risk asymptomatic subjects in the United States aged 50 years. Enrollees in the American College of Radiology Imaging Network National CT Colonography Trial provided informed consent, and approval was obtained from the institutional review board at each site. CT colonography performance estimates from the trial were incorporated into three Cancer Intervention and Surveillance Modeling Network CRC microsimulations. Simulated survival and lifetime costs for screening 50-year-old subjects in the United States with CT colonography every 5 or 10 years were compared with those for guideline-concordant screening with colonoscopy, flexible sigmoidoscopy plus either sensitive unrehydrated fecal occult blood testing (FOBT) or fecal immunochemical testing (FIT), and no screening. Perfect and reduced screening adherence scenarios were considered. Incremental cost-effectiveness and net health benefits were estimated from the U.S. health care sector perspective, assuming a 3% discount rate. CT colonography at 5- and 10-year screening intervals was more costly and less effective than FOBT plus flexible sigmoidoscopy in all three models in both 100% and 50% adherence scenarios. Colonoscopy also was more costly and less effective than FOBT plus flexible sigmoidoscopy, except in the CRC-SPIN model assuming 100% adherence (incremental cost-effectiveness ratio: $26,300 per life-year gained). CT colonography at 5- and 10-year screening intervals and colonoscopy were net beneficial compared with no screening in all model scenarios. The 5-year screening interval was net beneficial over the 10-year interval except in the MISCAN model when assuming 100% adherence and willingness to pay $50,000 per life-year gained. All three models predict CT colonography to be more costly and less effective than non-CT colonographic screening but net beneficial compared with no screening given model assumptions. RSNA, 2011

Procalcitonin Biomarker Algorithm Reduces Antibiotic Prescriptions, Duration of Therapy, and Costs in Chronic Obstructive Pulmonary Disease: A Comparison in the Netherlands, Germany, and the United Kingdom.

PubMed

van der Maas, Marloes E; Mantjes, Gertjan; Steuten, Lotte M G

2017-04-01

Antibiotics are often recommended as treatment for patients with chronic obstructive pulmonary disease (COPD) exacerbations. However, not all COPD exacerbations are caused by bacterial infections and there is consequently considerable misuse and overuse of antibiotics among patients with COPD. This poses a severe burden on healthcare resources such as increased risk of developing antibiotic resistance. The biomarker procalcitonin (PCT) displays specificity to distinguish bacterial inflammations from nonbacterial inflammations and may therefore help to rationalize antibiotic prescriptions. We report in this study, a three-country comparison of the health and economic consequences of a PCT biomarker-guided prescription and clinical decision-making strategy compared to current practice in hospitalized patients with COPD exacerbations. A decision tree was developed, comparing the expected costs and effects of the PCT algorithm to current practice in the Netherlands, Germany, and the United Kingdom. The time horizon of the model captured the length of hospital stay and a societal perspective was also adopted. The primary health outcome was the duration of antibiotic therapy. The incremental cost-effectiveness ratio was defined as the incremental costs per antibiotic day avoided. The incremental cost savings per day on antibiotic therapy avoided were (in Euros) €90 in the Netherlands, €125 in Germany, and €52 in the United Kingdom. Probabilistic sensitivity analyses showed that in the majority of simulations, the PCT biomarker strategy was superior to current practice (the Netherlands: 58%, Germany: 58%, and the United Kingdom: 57%). In conclusion, the PCT biomarker algorithm to optimize antibiotic prescriptions in COPD is likely to be cost-effective compared to current practice. Both the percentage of patients who start with antibiotic treatment as well as the duration of antibiotic therapy are reduced with the PCT decision algorithm, leading to a decrease in total costs per patient. Economic analysis based on real-life data is recommended for further research. Biomarker-driven prescription algorithms are important instruments for personalized medicine in COPD. This also attests to the emerging convergence of biomarker innovations and the broader field of Health Technology Assessment (HTA).

Surveillance-guided selective digestive decontamination of carbapenem-resistant Enterobacteriaceae in the intensive care unit: A cost-effectiveness analysis.

PubMed

You, Joyce H S; Li, Hong-Kiu; Ip, Margaret

2018-03-01

Clinical findings have shown effectiveness and safety of selective digestive decontamination (SDD) for eradication of carbapenem-resistant Enterobacteriaceae (CRE) in high-risk carriers. We aimed to evaluate the cost-effectiveness of SDD guided by CRE surveillance in the intensive care unit (ICU). Outcomes of surveillance-guided SDD (test-guided SDD) and no screening (control) in the ICU were compared by Markov model simulations. Model outcomes were CRE infection and mortality rates, direct costs, and quality-adjusted life year (QALY) loss. Model inputs were estimated from clinical literature. Sensitivity analyses were conducted to examine the robustness of base case results. Test-guided SDD reduced infection (4.8% vs 5.0%) and mortality (1.8% vs 2.1%) rates at a higher cost ($1,102 vs $1,074) than the control group in base case analysis, respectively. Incremental cost per QALY saved (incremental cost-effectiveness ratio [ICER]) by the test-guided SDD group was $557 per QALY. Probabilistic sensitivity analysis showed that test-guided SDD was effective in saving QALYs in 100% of 10,000 Monte Carlo simulations, and cost-saving 59.1% of time. The remaining 40.9% of simulations found SDD to be effective at an additional cost, with ICERs accepted as cost-effective per the willingness-to-pay threshold. Surveillance-guided SDD appears to be cost-effective in reducing CRE infection and mortality with QALYs saved. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Cost-effectiveness Analysis of Sacubitril/Valsartan vs Enalapril in Patients With Heart Failure and Reduced Ejection Fraction.

PubMed

Gaziano, Thomas A; Fonarow, Gregg C; Claggett, Brian; Chan, Wing W; Deschaseaux-Voinet, Celine; Turner, Stuart J; Rouleau, Jean L; Zile, Michael R; McMurray, John J V; Solomon, Scott D

2016-09-01

The angiotensin receptor neprilysin inhibitor sacubitril/valsartan was associated with a reduction in cardiovascular mortality, all-cause mortality, and hospitalizations compared with enalapril. Sacubitril/valsartan has been approved for use in heart failure (HF) with reduced ejection fraction in the United States and cost has been suggested as 1 factor that will influence the use of this agent. To estimate the cost-effectiveness of sacubitril/valsartan vs enalapril in the United States. Data from US adults (mean [SD] age, 63.8 [11.5] years) with HF with reduced ejection fraction and characteristics similar to those in the PARADIGM-HF trial were used as inputs for a 2-state Markov model simulated HF. Risks of all-cause mortality and hospitalization from HF or other reasons were estimated with a 30-year time horizon. Quality of life was based on trial EQ-5D scores. Hospital costs combined Medicare and private insurance reimbursement rates; medication costs included the wholesale acquisition cost for sacubitril/valsartan and enalapril. A discount rate of 3% was used. Sensitivity analyses were performed on key inputs including: hospital costs, mortality benefit, hazard ratio for hospitalization reduction, drug costs, and quality-of-life estimates. Hospitalizations, quality-adjusted life-years (QALYs), costs, and incremental costs per QALY gained. The 2-state Markov model of US adult patients (mean age, 63.8 years) calculated that there would be 220 fewer hospital admissions per 1000 patients with HF treated with sacubitril/valsartan vs enalapril over 30 years. The incremental costs and QALYs gained with sacubitril/valsartan treatment were estimated at $35 512 and 0.78, respectively, compared with enalapril, equating to an incremental cost-effectiveness ratio (ICER) of $45 017 per QALY for the base-case. Sensitivity analyses demonstrated ICERs ranging from $35 357 to $75 301 per QALY. For eligible patients with HF with reduced ejection fraction, the Markov model calculated that sacubitril/valsartan would increase life expectancy at an ICER consistent with other high-value accepted cardiovascular interventions. Sensitivity analyses demonstrated sacubitril/valsartan would remain cost-effective vs enalapril.

Item hierarchy-based analysis of the Rivermead Mobility Index resulted in improved interpretation and enabled faster scoring in patients undergoing rehabilitation after stroke.

PubMed

Roorda, Leo D; Green, John R; Houwink, Annemieke; Bagley, Pam J; Smith, Jane; Molenaar, Ivo W; Geurts, Alexander C

2012-06-01

To enable improved interpretation of the total score and faster scoring of the Rivermead Mobility Index (RMI) by studying item ordering or hierarchy and formulating start-and-stop rules in patients after stroke. Cohort study. Rehabilitation center in the Netherlands; stroke rehabilitation units and the community in the United Kingdom. Item hierarchy of the RMI was studied in an initial group of patients (n=620; mean age ± SD, 69.2±12.5y; 297 [48%] men; 304 [49%] left hemisphere lesion, and 269 [43%] right hemisphere lesion), and the adequacy of the item hierarchy-based start-and-stop rules was checked in a second group of patients (n=237; mean age ± SD, 60.0±11.3y; 139 [59%] men; 103 [44%] left hemisphere lesion, and 93 [39%] right hemisphere lesion) undergoing rehabilitation after stroke. Not applicable. Mokken scale analysis was used to investigate the fit of the double monotonicity model, indicating hierarchical item ordering. The percentages of patients with a difference between the RMI total score and the scores based on the start-and-stop rules were calculated to check the adequacy of these rules. The RMI had good fit of the double monotonicity model (coefficient H(T)=.87). The interpretation of the total score improved. Item hierarchy-based start-and-stop rules were formulated. The percentages of patients with a difference between the RMI total score and the score based on the recommended start-and-stop rules were 3% and 5%, respectively. Ten of the original 15 items had to be scored after applying the start-and-stop rules. Item hierarchy was established, enabling improved interpretation and faster scoring of the RMI. Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

Comparing cost-effectiveness of X-Stop with minimally invasive decompression in lumbar spinal stenosis: a randomized controlled trial.

PubMed

Lønne, Greger; Johnsen, Lars Gunnar; Aas, Eline; Lydersen, Stian; Andresen, Hege; Rønning, Roar; Nygaard, Øystein P

2015-04-15

Randomized clinical trial with 2-year follow-up. To compare the cost-effectiveness of X-stop to minimally invasive decompression in patients with symptomatic lumbar spinal stenosis. Lumbar spinal stenosis is the most common indication for operative treatment in elderly. Although surgery is more costly than nonoperative treatment, health outcomes for more than 2 years were shown to be significantly better. Surgical treatment with minimally invasive decompression is widely used. X-stop is introduced as another minimally invasive technique showing good results compared with nonoperative treatment. We enrolled 96 patients aged 50 to 85 years, with symptoms of neurogenic intermittent claudication within 250-m walking distance and 1- or 2-level lumbar spinal stenosis, randomized to either minimally invasive decompression or X-stop. Quality-adjusted life-years were based on EuroQol EQ-5D. The hospital unit costs were estimated by means of the top-down approach. Each cost unit was converted into a monetary value by dividing the overall cost by the amount of cost units produced. The analysis of costs and health outcomes is presented by the incremental cost-effectiveness ratio. The study was terminated after a midway interim analysis because of significantly higher reoperation rate in the X-stop group (33%). The incremental cost for X-stop compared with minimally invasive decompression was &OV0556;2832 (95% confidence interval: 1886-3778), whereas the incremental health gain was 0.11 quality-adjusted life-year (95% confidence interval: -0.01 to 0.23). Based on the incremental cost and effect, the incremental cost-effectiveness ratio was &OV0556;25,700. The majority of the bootstrap samples displayed in the northeast corner of the cost-effectiveness plane, giving a 50% likelihood that X-stop is cost-effective at the extra cost of &OV0556;25,700 (incremental cost-effectiveness ratio) for a quality-adjusted life-year. The significantly higher cost of X-stop is mainly due to implant cost and the significantly higher reoperation rate. 2.

International Space Station Increment-2 Quick Look Report

NASA Technical Reports Server (NTRS)

Jules, Kenol; Hrovat, Kenneth; Kelly, Eric

2001-01-01

The objective of this quick look report is to disseminate the International Space Station (ISS) Increment-2 reduced gravity environment preliminary analysis in a timely manner to the microgravity scientific community. This report is a quick look at the processed acceleration data collected by the Microgravity Acceleration Measurement System (MAMS) during the period of May 3 to June 8, 2001. The report is by no means an exhaustive examination of all the relevant activities, which occurred during the time span mentioned above for two reasons. First, the time span being considered in this report is rather short since the MAMS was not active throughout the time span being considered to allow a detailed characterization. Second, as the name of the report implied, it is a quick look at the acceleration data. Consequently, a more comprehensive report, the ISS Increment-2 report, will be published following the conclusion of the Increment-2 tour of duty. NASA sponsors the MAMS and the Space Acceleration Microgravity System (SAMS) to support microgravity science experiments, which require microgravity acceleration measurements. On April 19, 2001, both the MAMS and the SAMS units were launched on STS-100 from the Kennedy Space Center for installation on the ISS. The MAMS unit was flown to the station in support of science experiments requiring quasisteady acceleration data measurements, while the SAMS unit was flown to support experiments requiring vibratory acceleration data measurement. Both acceleration systems are also used in support of the vehicle microgravity requirements verification. The ISS reduced gravity environment analysis presented in this report uses mostly the MAMS acceleration data measurements (the Increment-2 report will cover both systems). The MAMS has two sensors. The MAMS Orbital Acceleration Research Experiment Sensor Subsystem, which is a low frequency range sensor (up to 1 Hz), is used to characterize the quasi-steady environment for payloads and vehicle. The MAMS High Resolution Acceleration Package is used to characterize the ISS vibratory environment up to 100 Hz. This quick look report presents some selected quasi-steady and vibratory activities recorded by the MAMS during the ongoing ISS Increment-2 tour of duty.

The effects of climate change on instream nitrogen transport in the contiguous United States

NASA Astrophysics Data System (ADS)

Alam, M. J.; Goodall, J. L.

2011-12-01

Excessive nitrogen loading has caused significant environmental impacts such as eutrophication and hypoxia in waterbodies around the world. Nitrogen loading is largely dependent on nonpoint source pollution and nitrogen transport from nonpoint source pollution is greatly impacted by climate conditions. For example, increased precipitation leads to more runoff and a higher nitrogen yield. However, higher temperatures also impact nitrogen transport in that higher temperatures increase denitrification and therefore reduce nitrogen yield. The purpose of this research is to quantify potential changes in nitrogen yield for the contiguous United States under predicted climate change scenarios, specifically changes in precipitation and air temperature. The analysis was performed for high (A2) and low (B1) emission scenarios and for the year 2030, 2050 and 2090. We used 11 different IPCC (The Intergovernmental Panel on Climate Change) models predicted precipitation and temperature estimates to capture uncertainty. The SPARROW model was calibrated using historical nitrogen loading data and used to predict nitrogen yields for future climate conditions. We held nitrogen source data constant in order to isolate the impact of predicted precipitation and temperature changes for each model scenario. Preliminary results suggest an overall decrease in nitrogen yield if climate change impacts are considered in isolation. For the A2 scenario, the model results indicated an overall incremental nitrogen yield decrease of 2-17% by the year 2030, 4-26% by the year 2050, and 11-45% by the year 2090. The B1 emission scenario also indicated an incremental yield decrease, but at lesser amounts of 2-18%, 5-21% and 10-38% by the years 2030, 2050, and 2090, respectively. This decrease is mainly due to higher predicted temperatures that result in increased denitrification rates.

Final Revisions Rule State Budgets and New Unit Set-Asides TSD

EPA Pesticide Factsheets

This technical support document shows the underlying data and calculations used to quantify the state budget revisions and new unit set-aside revisions made in the final revisions rule, as well as those revisions included in the direct final revisions rule

Summary of Recent Research Accomplishment Onboard the International Space Station—Within the United States Orbital Segment

NASA Astrophysics Data System (ADS)

Jules, Kenol; Istasse, Eric; Stenuit, Hilde; Murakami, Keiji; Yoshizaki, Izumi; Johnson-Green, Perry

2011-06-01

November 20, 2010, marked a significant milestone in the annals of human endeavors in space since it was the twelfth anniversary of one of the most challenging and complex construction projects ever attempted by humans away from our planet: The construction of the International Space Stations. On November 20, 1998, the Zarya Control Module was launched. With this simple, almost unnoticed launch in the science community, the construction of a continuously staffed research platform, in Low Earth Orbit, was underway. This paper discusses the research that was performed by many occupants of this research platform during the year celebrating its twelfth anniversary. The main objectives of this paper are fourfold: (1) to discuss the integrated manner in which science planning/replanning and prioritization during the execution phase of an increment is carried out across the United States Orbital Segment since that segment is made of four independent space agencies; (2) to discuss and summarize the research that was performed during increments 16 and 17 (October 2007 to October 2008). The discussion for these two increments is primarily focused on the main objectives of each investigation and its associated hypotheses that were investigated. Whenever available and approved, preliminary research results are also discussed for each of the investigations performed during these two increments; (3) to compare the planned research portfolio for these two increments versus what was actually accomplished during the execution phase in order to discuss the challenges associated with planning and performing research in a space laboratory located over 240 miles up in space, away from the ground support team; (4) to briefly touch on the research portfolio of increments 18 and 19/20 as the International Space Station begins its next decade in Low Earth Orbit.

Health care resource use, health care expenditures and absenteeism costs associated with osteoarthritis in US healthcare system.

PubMed

Menon, J; Mishra, P

2018-04-01

We determined incremental health care resource utilization, incremental health care expenditures, incremental absenteeism, and incremental absenteeism costs associated with osteoarthritis. Medical Expenditure Panel Survey (MEPS) for 2011 was used as data source. Individuals 18 years or older and employed during 2011 were eligible for inclusion in the sample for analyses. Individuals with osteoarthritis were identified based on ICD-9-CM codes. Incremental health care resource utilization included annual hospitalization, hospital days, emergency room visits and outpatient visits. Incremental health expenditures included annual inpatient, outpatient, emergency room, medications, miscellaneous and annual total expenditures. Of the total sample, 1354 were diagnosed with osteoarthritis, and compared to non osteoarthritis individuals. Incremental resource utilization, expenditures, absenteeism and absenteeism costs were estimated using regression models, adjusting for age, gender, sex, region, marital status, insurance coverage, comorbidities, anxiety, asthma, hypertension and hyperlipidemia. Regression models revealed incremental mean annual resource use associated with osteoarthritis of 0.07 hospitalizations, equal to 70 additional hospitalizations per 100 osteoarthritic patients annually, and 3.63 outpatient visits, equal to 363 additional visits per 100 osteoarthritic patients annually. Mean annual incremental total expenditures associated with osteoarthritis were $2046. Annually, mean incremental expenditures were largest for inpatient expenditures at $826, followed by mean incremental outpatient expenditures of $659, and mean incremental medication expenditures of $325. Mean annual incremental absenteeism was 2.2 days and mean annual incremental absenteeism costs were $715.74. Total direct expenditures were estimated at $41.7 billion. Osteoarthritis was associated with significant incremental health care resource utilization, expenditures, absenteeism and absenteeism costs. Copyright © 2017 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

Potential Implications of Approaches to Climate Change on the Clean Water Rule Definition of "Waters of the United States".

PubMed

Faust, Derek R; Moore, Matthew T; Emison, Gerald Andrews; Rush, Scott A

2016-05-01

The 1972 Clean Water Act was passed to protect chemical, physical, and biological integrity of United States' waters. The U.S. Environmental Protection Agency and U.S. Army Corps of Engineers codified a new "waters of the United States" rule on June 29, 2015, because several Supreme Court case decisions caused confusion with the existing rule. Climate change could affect this rule through connectivity between groundwater and surface waters; floodplain waters and the 100-year floodplain; changes in jurisdictional status; and sea level rise on coastal ecosystems. Four approaches are discussed for handling these implications: (1) "Wait and see"; (2) changes to the rule; (3) use guidance documents; (4) Congress statutorily defining "waters of the United States." The approach chosen should be legally defensible and achieved in a timely fashion to provide protection to "waters of the United States" in proactive consideration of scientifically documented effects of climate change on aquatic ecosystems.

Incremental health care utilization and expenditures for chronic rhinosinusitis in the United States.

PubMed

Bhattacharyya, Neil

2011-07-01

I determined incremental increases in health care expenditures and utilization associated with chronic rhinosinusitis (CRS). Patients with a reported diagnosis of CRS were extracted from the 2007 Medical Expenditure Panel Survey medical conditions file and linked to the consolidated expenditures file. The patients with CRS were then compared to patients without CRS to determine differences in health care utilization (office visits,emergency facility visits, and prescriptions filled), as well as differences in health care expenditures (total health care costs, office visit costs, prescription medication costs, and self-expenditures) by use of demographically adjusted and comorbidity-adjusted multivariate models. An estimated 11.1+/-0.48 million adult patients reported having CRS in 2007 (4.9%+/-0.2% of the US population). The additional incremental health care utilizations associated with CRS relative to patients without CRS for office visits, emergency facility visits, and number of prescriptions filled were 3.45+/-0.42, 0.09+/-0.03, and 5.5+/-0.8, respectively (all p

Rule induction performance in amnestic mild cognitive impairment and Alzheimer's dementia: examining the role of simple and biconditional rule learning processes.

PubMed

Oosterman, Joukje M; Heringa, Sophie M; Kessels, Roy P C; Biessels, Geert Jan; Koek, Huiberdina L; Maes, Joseph H R; van den Berg, Esther

2017-04-01

Rule induction tests such as the Wisconsin Card Sorting Test require executive control processes, but also the learning and memorization of simple stimulus-response rules. In this study, we examined the contribution of diminished learning and memorization of simple rules to complex rule induction test performance in patients with amnestic mild cognitive impairment (aMCI) or Alzheimer's dementia (AD). Twenty-six aMCI patients, 39 AD patients, and 32 control participants were included. A task was used in which the memory load and the complexity of the rules were independently manipulated. This task consisted of three conditions: a simple two-rule learning condition (Condition 1), a simple four-rule learning condition (inducing an increase in memory load, Condition 2), and a complex biconditional four-rule learning condition-inducing an increase in complexity and, hence, executive control load (Condition 3). Performance of AD patients declined disproportionately when the number of simple rules that had to be memorized increased (from Condition 1 to 2). An additional increment in complexity (from Condition 2 to 3) did not, however, disproportionately affect performance of the patients. Performance of the aMCI patients did not differ from that of the control participants. In the patient group, correlation analysis showed that memory performance correlated with Condition 1 performance, whereas executive task performance correlated with Condition 2 performance. These results indicate that the reduced learning and memorization of underlying task rules explains a significant part of the diminished complex rule induction performance commonly reported in AD, although results from the correlation analysis suggest involvement of executive control functions as well. Taken together, these findings suggest that care is needed when interpreting rule induction task performance in terms of executive function deficits in these patients.

40 CFR 62.14575 - What must I do if I close my CISWI unit and then restart it?

Code of Federal Regulations, 2013 CFR

2013-07-01

... FACILITIES AND POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That Commenced Construction On or Before November 30, 1999 Compliance Schedule and Increments of... retrofit construction of control devices so that when the affected CISWI unit is brought online, all...

40 CFR Table 8 to Subpart Bbbb of... - Model Rule-Requirements for Stack Tests

Code of Federal Regulations, 2010 CFR

2010-07-01

... at full load. 2. Metals Cadmium Method 1 Method 29 a Compliance testing must be performed while the... be performed while the municipal waste combustion unit is operating at full load. Mercury Method 1...

40 CFR 60.1860 - What reports must I submit and in what form?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule... §§ 60.1870, 60.1880, and 60.1895. If the Administrator agrees, you may submit electronic reports. (c...

40 CFR 60.1860 - What reports must I submit and in what form?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule... §§ 60.1870, 60.1880, and 60.1895. If the Administrator agrees, you may submit electronic reports. (c...

40 CFR 60.1860 - What reports must I submit and in what form?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule... §§ 60.1870, 60.1880, and 60.1895. If the Administrator agrees, you may submit electronic reports. (c...

40 CFR 60.1860 - What reports must I submit and in what form?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule... §§ 60.1870, 60.1880, and 60.1895. If the Administrator agrees, you may submit electronic reports. (c...

40 CFR 60.1860 - What reports must I submit and in what form?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule... §§ 60.1870, 60.1880, and 60.1895. If the Administrator agrees, you may submit electronic reports. (c...

Broad Learning System: An Effective and Efficient Incremental Learning System Without the Need for Deep Architecture.

PubMed

Chen, C L Philip; Liu, Zhulin

2018-01-01

Broad Learning System (BLS) that aims to offer an alternative way of learning in deep structure is proposed in this paper. Deep structure and learning suffer from a time-consuming training process because of a large number of connecting parameters in filters and layers. Moreover, it encounters a complete retraining process if the structure is not sufficient to model the system. The BLS is established in the form of a flat network, where the original inputs are transferred and placed as "mapped features" in feature nodes and the structure is expanded in wide sense in the "enhancement nodes." The incremental learning algorithms are developed for fast remodeling in broad expansion without a retraining process if the network deems to be expanded. Two incremental learning algorithms are given for both the increment of the feature nodes (or filters in deep structure) and the increment of the enhancement nodes. The designed model and algorithms are very versatile for selecting a model rapidly. In addition, another incremental learning is developed for a system that has been modeled encounters a new incoming input. Specifically, the system can be remodeled in an incremental way without the entire retraining from the beginning. Satisfactory result for model reduction using singular value decomposition is conducted to simplify the final structure. Compared with existing deep neural networks, experimental results on the Modified National Institute of Standards and Technology database and NYU NORB object recognition dataset benchmark data demonstrate the effectiveness of the proposed BLS.

Health information technology: initial set of standards, implementation specifications, and certification criteria for electronic health record technology. Interim final rule.

PubMed

2010-01-13

The Department of Health and Human Services (HHS) is issuing this interim final rule with a request for comments to adopt an initial set of standards, implementation specifications, and certification criteria, as required by section 3004(b)(1) of the Public Health Service Act. This interim final rule represents the first step in an incremental approach to adopting standards, implementation specifications, and certification criteria to enhance the interoperability, functionality, utility, and security of health information technology and to support its meaningful use. The certification criteria adopted in this initial set establish the capabilities and related standards that certified electronic health record (EHR) technology will need to include in order to, at a minimum, support the achievement of the proposed meaningful use Stage 1 (beginning in 2011) by eligible professionals and eligible hospitals under the Medicare and Medicaid EHR Incentive Programs.

40 CFR Table 3 to Subpart Dddd of... - Model Rule-Operating Limits for Wet Scrubbers

Code of Federal Regulations, 2010 CFR

2010-07-01

... Scrubbers 3 Table 3 to Subpart DDDD of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...—Model Rule—Operating Limits for Wet Scrubbers For these operating parameters You must establish these... intermittent units) a Pressure drop across the wet scrubber or amperage to wet scrubber Minimum pressure drop...

40 CFR Table 3 to Subpart Dddd of... - Model Rule-Operating Limits for Wet Scrubbers

Code of Federal Regulations, 2011 CFR

2011-07-01

... Scrubbers 3 Table 3 to Subpart DDDD of Part 60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...—Model Rule—Operating Limits for Wet Scrubbers For these operating parameters You must establish these... intermittent units) a Pressure drop across the wet scrubber or amperage to wet scrubber Minimum pressure drop...

Effect of age and gender on the number of motor units in healthy subjects estimated by the multipoint incremental MUNE method.

PubMed

Gawel, Malgorzata; Kostera-Pruszczyk, Anna

2014-06-01

Motor unit number estimation (MUNE) is a tool for estimating the number of motor units. The aim was to evaluate the multipoint incremental MUNE method in a healthy population, to analyze whether aging, gender, and the dominant hand side influence the motor unit number, and to assess reproducibility of MUNE with the Shefner modification. We studied 60 volunteers (mean age, 47 ± 17.7 years) in four groups aged 18 to 30, 31 to 45, 46 to 60, and above 60 years. Motor unit number estimation was calculated in the abductor pollicis brevis (APB) and the abductor digiti minimi (ADM) by dividing the single motor unit action potential amplitude into the maximal compound motor action potential amplitude. Test-retest variability was 7%. The mean value of MUNE for APB was 133.2 ± 43 and for ADM was 157.1 ± 39.4. Significant differences in MUNE results were found between groups aged 18 to 30 and 60 years or older and between groups aged 31 to 45 and 60 years or older. Motor unit number estimation results correlated negatively with the age of subjects for both APB and ADM. Single motor unit action potential, reflecting the size of motor unit, increased with the age of subjects only in APB. Compound motor action potential amplitude correlated negatively with the age of subjects in APB and ADM. Significant correlations were seen between MUNE in APB or ADM and compound motor action potential amplitude in these muscles and the age of female subjects. A similar relationship was not found in males. Multipoint incremental MUNE method with the Shefner modification is a noninvasive, easy to perform method with high reproducibility. The loss of motor neurons because of aging could be confirmed by our MUNE study and seems to be more pronounced in females.

78 FR 77492 - Hearings of the Judicial Conference Advisory Committee on Rules of Bankruptcy Procedure; Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-23

... JUDICIAL CONFERENCE OF THE UNITED STATES Hearings of the Judicial Conference Advisory Committee on...: Advisory Committee on Rules of Bankruptcy Procedure, Judicial Conference of the United States. ACTION..., 2014, Chicago, IL. FOR FURTHER INFORMATION CONTACT: Jonathan C. Rose, Secretary and Chief Rules Officer...

22 CFR 228.13 - Special source rules requiring procurement from the United States.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Special source rules requiring procurement from the United States. 228.13 Section 228.13 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND NATIONALITY FOR COMMODITIES AND SERVICES FINANCED BY USAID Conditions Governing...

Resistance-surface-based wildlife conservation connectivity modeling: Summary of efforts in the United States and guide for practitioners

Treesearch

Alisa A. Wade; Kevin S. McKelvey; Michael K. Schwartz

2015-01-01

Resistance-surface-based connectivity modeling has become a widespread tool for conservation planning. The current ease with which connectivity models can be created, however, masks the numerous untested assumptions underlying both the rules that produce the resistance surface and the algorithms used to locate low-cost paths across the target landscape. Here we present...

On the validity of the incremental approach to estimate the impact of cities on air quality

NASA Astrophysics Data System (ADS)

Thunis, Philippe

2018-01-01

The question of how much cities are the sources of their own air pollution is not only theoretical as it is critical to the design of effective strategies for urban air quality planning. In this work, we assess the validity of the commonly used incremental approach to estimate the likely impact of cities on their air pollution. With the incremental approach, the city impact (i.e. the concentration change generated by the city emissions) is estimated as the concentration difference between a rural background and an urban background location, also known as the urban increment. We show that the city impact is in reality made up of the urban increment and two additional components and consequently two assumptions need to be fulfilled for the urban increment to be representative of the urban impact. The first assumption is that the rural background location is not influenced by emissions from within the city whereas the second requires that background concentration levels, obtained with zero city emissions, are equal at both locations. Because the urban impact is not measurable, the SHERPA modelling approach, based on a full air quality modelling system, is used in this work to assess the validity of these assumptions for some European cities. Results indicate that for PM2.5, these two assumptions are far from being fulfilled for many large or medium city sizes. For this type of cities, urban increments are largely underestimating city impacts. Although results are in better agreement for NO2, similar issues are met. In many situations the incremental approach is therefore not an adequate estimate of the urban impact on air pollution. This poses issues in terms of interpretation when these increments are used to define strategic options in terms of air quality planning. We finally illustrate the interest of comparing modelled and measured increments to improve our confidence in the model results.

International Space Station Increment-2 Microgravity Environment Summary Report

NASA Technical Reports Server (NTRS)

Jules, Kenol; Hrovat, Kenneth; Kelly, Eric; McPherson, Kevin; Reckart, Timothy

2002-01-01

This summary report presents the results of some of the processed acceleration data, collected aboard the International Space Station during the period of May to August 2001, the Increment-2 phase of the station. Two accelerometer systems were used to measure the acceleration levels during activities that took place during the Increment-2 segment. However, not all of the activities were analyzed for this report due to time constraints, lack of precise information regarding some payload operations and other station activities. The National Aeronautics and Space Administration sponsors the Microgravity Acceleration Measurement System and the Space Acceleration Microgravity System to support microgravity science experiments, which require microgravity acceleration measurements. On April 19, 2001, both the Microgravity Acceleration Measurement System and the Space Acceleration Measurement System units were launched on STS-100 from the Kennedy Space Center for installation on the International Space Station. The Microgravity Acceleration Measurement System unit was flown to the station in support of science experiments requiring quasi-steady acceleration measurements, while the Space Acceleration Measurement System unit was flown to support experiments requiring vibratory acceleration measurement. Both acceleration systems are also used in support of vehicle microgravity requirements verification. The International Space Station Increment-2 reduced gravity environment analysis presented in this report uses acceleration data collected by both sets of accelerometer systems: 1) The Microgravity Acceleration Measurement System, which consists of two sensors: the Orbital Acceleration Research Experiment Sensor Subsystem, a low frequency range sensor (up to 1 Hz), is used to characterize the quasi-steady environment for payloads and the vehicle, and the High Resolution Accelerometer Package, which is used to characterize the vibratory environment up to 100 Hz. 2) The Space Acceleration Measurement System, which is a high frequency sensor, measures vibratory acceleration data in the range of 0.01 to 300 Hz. This summary report presents analysis of some selected quasisteady and vibratory activities measured by these accelerometers during Increment-2 from May to August 20, 2001.

Distributed Common Ground System - Army Increment 2 (DCGS-A Inc 2)

DTIC Science & Technology

2016-03-01

2016 Major Automated Information System Annual Report Distributed Common Ground System - Army Increment 2 ( DCGS -A Inc 2) Defense Acquisition...Management Information Retrieval (DAMIR) UNCLASSIFIED DCGS -A Inc 2 2016 MAR UNCLASSIFIED 2 Table of Contents Common Acronyms and Abbreviations...Determined TY - Then Year U.S.C- United States Code USD(AT&L) - Under Secretary of Defense for Acquisition, Technology, & Logistics DCGS -A Inc 2

Can contrast media increase organ doses in CT examinations? A clinical study.

PubMed

Amato, Ernesto; Salamone, Ignazio; Naso, Serena; Bottari, Antonio; Gaeta, Michele; Blandino, Alfredo

2013-06-01

The purpose of this article is to quantify the CT radiation dose increment in five organs resulting from the administration of iodinated contrast medium. Forty consecutive patients who underwent both un-enhanced and contrast-enhanced thoracoabdominal CT were included in our retrospective study. The dose increase between CT before and after contrast agent administration was evaluated in the portal phase for the thyroid, liver, spleen, pancreas, and kidneys by applying a previously validated method. An increase in radiation dose was noted in all organs studied. Average dose increments were 19% for liver, 71% for kidneys, 33% for spleen and pancreas, and 41% for thyroid. Kidneys exhibited the maximum dose increment, whereas the pancreas showed the widest variance because of the differences in fibro-fatty involution. Finally, thyroids with high attenuation values on unenhanced CT showed a lower Hounsfield unit increase and, thus, a smaller increment in the dose. Our study showed an increase in radiation dose in several parenchymatous tissues on contrast-enhanced CT. Our method allowed us to evaluate the dose increase from the change in attenuation measured in Hounsfield units. Because diagnostic protocols require multiple acquisitions after the contrast agent administration, such a dose increase should be considered when optimizing these protocols.

Different recognition cues reveal the decision rules used for egg rejection by hosts of a variably mimetic avian brood parasite.

PubMed

de la Colina, M Alicia; Pompilio, Lorena; Hauber, Mark E; Reboreda, Juan C; Mahler, Bettina

2012-09-01

Brood parasitism imposes several fitness costs on the host species. To reduce these costs, hosts of avian brood parasites have evolved various defenses, of which egg rejection is the most prevalent. In the face of variable host-parasite mimicry and the costs of egg discrimination itself, many hosts reject only some foreign eggs. Here, we experimentally varied the recognition cues to study the underlying cognitive mechanisms used by the Chalk-browed Mockingbird (Mimus saturninus) to reject the white immaculate eggs laid by the parasitic Shiny Cowbird (Molothrus bonariensis). Immaculate eggs are the only parasite eggs rejected by this host, as it accepts all polymorphic, spotted eggs laid by cowbirds. Using a within-breeding pair experimental design, we tested for the salience of spotting, UV reflectance, and brightness in eliciting rejection. We found that the presence of spotting significantly decreased the probability of rejection while increments in brightness significantly increased rejection frequencies. The cognitive rules underlying mockingbird rejection behavior can be explained by a decision-making model which predicts changes in the levels of rejection in direct relation to the number of relevant attributes shared between host and parasite eggs.

Incremental terrain processing for large digital elevation models

NASA Astrophysics Data System (ADS)

Ye, Z.

2012-12-01

Incremental terrain processing for large digital elevation models Zichuan Ye, Dean Djokic, Lori Armstrong Esri, 380 New York Street, Redlands, CA 92373, USA (E-mail: zye@esri.com, ddjokic@esri.com , larmstrong@esri.com) Efficient analyses of large digital elevation models (DEM) require generation of additional DEM artifacts such as flow direction, flow accumulation and other DEM derivatives. When the DEMs to analyze have a large number of grid cells (usually > 1,000,000,000) the generation of these DEM derivatives is either impractical (it takes too long) or impossible (software is incapable of processing such a large number of cells). Different strategies and algorithms can be put in place to alleviate this situation. This paper describes an approach where the overall DEM is partitioned in smaller processing units that can be efficiently processed. The processed DEM derivatives for each partition can then be either mosaicked back into a single large entity or managed on partition level. For dendritic terrain morphologies, the way in which partitions are to be derived and the order in which they are to be processed depend on the river and catchment patterns. These patterns are not available until flow pattern of the whole region is created, which in turn cannot be established upfront due to the size issues. This paper describes a procedure that solves this problem: (1) Resample the original large DEM grid so that the total number of cells is reduced to a level for which the drainage pattern can be established. (2) Run standard terrain preprocessing operations on the resampled DEM to generate the river and catchment system. (3) Define the processing units and their processing order based on the river and catchment system created in step (2). (4) Based on the processing order, apply the analysis, i.e., flow accumulation operation to each of the processing units, at the full resolution DEM. (5) As each processing unit is processed based on the processing order defined in (3), compare the resulting drainage pattern with the drainage pattern established at the coarser scale and adjust the drainage boundaries and rivers if necessary.

40 CFR 60.2660 - What site-specific documentation is required?

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training... and are suitable for inspection upon request. (1) Summary of the applicable standards under this...

40 CFR 60.2785 - What else must I report if I have a deviation from the requirement to have a qualified operator...

Code of Federal Regulations, 2013 CFR

2013-07-01

... of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF... Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2785 What else must I report...

40 CFR 60.2785 - What else must I report if I have a deviation from the requirement to have a qualified operator...

Code of Federal Regulations, 2014 CFR

2014-07-01

... of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF... Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2785 What else must I report...

40 CFR 60.2660 - What site-specific documentation is required?

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Operator Training... and are suitable for inspection upon request. (1) Summary of the applicable standards under this...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Continuous... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Continuous... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

40 CFR 60.1770 - What must I do if any of my continuous emission monitoring systems are temporarily unavailable to...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Model Rule-Continuous... alternate methods for collecting data when systems malfunction or when repairs, calibration checks, or zero...

40 CFR Table 3 to Subpart Ffff of... - Model Rule-Operating Limits for Incinerators and Wet Scrubbers

Code of Federal Regulations, 2012 CFR

2012-07-01

... Emission Guidelines and Compliance Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004 Pt. 60, Subpt. FFFF, Table 3 Table 3 to Subpart FFFF of Part 60...

40 CFR Table 3 to Subpart Ffff of... - Model Rule-Operating Limits for Incinerators and Wet Scrubbers

Code of Federal Regulations, 2013 CFR

2013-07-01

... Emission Guidelines and Compliance Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004 Pt. 60, Subpt. FFFF, Table 3 Table 3 to Subpart FFFF of Part 60...

40 CFR Table 3 to Subpart Ffff of... - Model Rule-Operating Limits for Incinerators and Wet Scrubbers

Code of Federal Regulations, 2014 CFR

2014-07-01

... Emission Guidelines and Compliance Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004 Pt. 60, Subpt. FFFF, Table 3 Table 3 to Subpart FFFF of Part 60...

Enabling Incremental Iterative Development at Scale: Quality Attribute Refinement and Allocation in Practice

DTIC Science & Technology

2015-06-01

abstract constraints along six dimen- sions for expansion: user, actions, data , business rules, interfaces, and quality attributes [Gottesdiener 2010...relevant open source systems. For example, the CONNECT and HADOOP Distributed File System (HDFS) projects have many user stories that deal with...Iteration Zero involves architecture planning before writing any code. An overly long Iteration Zero is equivalent to the dysfunctional “ Big Up-Front

A new in silico classification model for ready biodegradability, based on molecular fragments.

PubMed

Lombardo, Anna; Pizzo, Fabiola; Benfenati, Emilio; Manganaro, Alberto; Ferrari, Thomas; Gini, Giuseppina

2014-08-01

Regulations such as the European REACH (Registration, Evaluation, Authorization and restriction of Chemicals) often require chemicals to be evaluated for ready biodegradability, to assess the potential risk for environmental and human health. Because not all chemicals can be tested, there is an increasing demand for tools for quick and inexpensive biodegradability screening, such as computer-based (in silico) theoretical models. We developed an in silico model starting from a dataset of 728 chemicals with ready biodegradability data (MITI-test Ministry of International Trade and Industry). We used the novel software SARpy to automatically extract, through a structural fragmentation process, a set of substructures statistically related to ready biodegradability. Then, we analysed these substructures in order to build some general rules. The model consists of a rule-set made up of the combination of the statistically relevant fragments and of the expert-based rules. The model gives good statistical performance with 92%, 82% and 76% accuracy on the training, test and external set respectively. These results are comparable with other in silico models like BIOWIN developed by the United States Environmental Protection Agency (EPA); moreover this new model includes an easily understandable explanation. Copyright © 2014 Elsevier Ltd. All rights reserved.

Petroleum Refineries (Catalytic Cracking, Catalytic Reforming and Sulfur Recovery Units): National Emission Standards for Hazardous Air Pollutants (NESHAP)

EPA Pesticide Factsheets

learn more about the NESHAP for catalytic cracking and reforming units, as well as sulfur recovery units in petroleum refineries by reading the rule history, rule summary, background information documents, and compliance information

Inventory-based sensitivity analysis of the Large Tree Diameter Growth Submodel of the Southern Variant of the FVS

Treesearch

Giorgio Vacchiano; John D. Shaw; R. Justin DeRose; James N. Long

2008-01-01

Diameter increment is an important variable in modeling tree growth. Most facets of predicted tree development are dependent in part on diameter or diameter increment, the most commonly measured stand variable. The behavior of the Forest Vegetation Simulator (FVS) largely relies on the performance of the diameter increment model and the subsequent use of predicted dbh...

The Conventional and Unconventional about Disability Conventions: A Reflective Analysis of United Nations Convention on the Rights of Persons with Disabilities

ERIC Educational Resources Information Center

Umeasiegbu, Veronica I.; Bishop, Malachy; Mpofu, Elias

2013-01-01

This article presents an analysis of the United Nations Convention on the Rights of Persons with Disabilities (CRPD) in relation to prior United Nations conventions on disability and U.S. disability policy law with a view to identifying the conventional and also the incremental advances of the CRPD. Previous United Nations conventions related to…

FY 1979 Unit Cost Analysis for the Public Community Colleges of Illinois.

ERIC Educational Resources Information Center

Illinois Community Coll. Board, Springfield.

A unit cost analysis for fiscal year (FY) 1979 was conducted by the Illinois Community College Board using mid-term enrollment data and uniform accounting information from each of the state's 51 community colleges. Unit costs for instructional areas were determined at three incremental levels: (1) net instructional cost (NIC), which includes…

Work and retirement among a cohort of older men in the United States, 1966-1983.

PubMed

Hayward, M D; Grady, W R

1990-08-01

Multivariate increment-decrement working life tables are estimated for a cohort of older men in the United States for the period 1966-1983. The approach taken allows multiple processes to be simultaneously incorporated into a single model, resulting in a more realistic portrayal of a cohort's late-life labor force behavior. In addition, because the life table model is developed from multivariate hazard equations, we identify the effects of sociodemographic characteristics on the potentially complex process by which the labor force career is ended. In contrast to the assumed homogeneity of previous working life table analyses, the present study shows marked differences in labor force mobility and working and nonworking life expectancy according to occupation, class of worker, education, race, and marital status. We briefly discuss the implications of these findings for inequities of access to retirement, private and public pension consumption, and future changes in the retirement process.

77 FR 72885 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... JUDICIAL CONFERENCE OF THE UNITED STATES Meeting of the Judicial Conference Committee on Rules of Practice and Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of... Science Drive, Durham, NC 27708. FOR FURTHER INFORMATION CONTACT: Jonathan C. Rose, Secretary and Chief...

78 FR 64012 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... JUDICIAL CONFERENCE OF THE UNITED STATES Meeting of the Judicial Conference Committee on Rules of Practice and Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of... Columbus Circle NE., Washington, DC 20544. FOR FURTHER INFORMATION CONTACT: Jonathan C. Rose, Secretary and...

78 FR 45564 - Meeting of the Judicial Conference Committee on Rules of Practice and Procedure

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

... States Courts, Washington, DC 20544, telephone (202) 502- 1820. Dated: July 24, 2013. Jonathan C. Rose... JUDICIAL CONFERENCE OF THE UNITED STATES Meeting of the Judicial Conference Committee on Rules of Practice and Procedure AGENCY: Judicial Conference of the United States Advisory Committee on Rules of...

Illegal Immigration in the United States: Implications for Rule of Law and National Security

DTIC Science & Technology

2012-02-15

AIR WAR COLLEGE AIR UNIVERSITY ILLEGAL IMMIGRATION IN THE UNITED STATES: IMPLICATIONS FOR RULE OF LAW AND NATIONAL SECURITY By Paul A...government’s failure to strictly enforce immigration laws presents national security vulnerabilities and is subversive to the rule of law . Without...the rule of law , serious social tensions will occur that impel states and localities to fill the void left by the lack of immigration enforcement. In

Integrated Reservoir Modeling of CO2-EOR Performance and Storage Potential in the Farnsworth Field Unit, Texas.

NASA Astrophysics Data System (ADS)

Ampomah, W.; Balch, R. S.; Cather, M.; Dai, Z.

2017-12-01

We present a performance assessment methodology and storage potential for CO2 enhanced oil recovery (EOR) in partially depleted reservoirs. A three dimensional heterogeneous reservoir model was developed based on geological, geophysics and engineering data from Farnsworth field Unit (FWU). The model aided in improved characterization of prominent rock properties within the Pennsylvanian aged Morrow sandstone reservoir. Seismic attributes illuminated previously unknown faults and structural elements within the field. A laboratory fluid analysis was tuned to an equation of state and subsequently used to predict the thermodynamic minimum miscible pressure (MMP). Datasets including net-to-gross ratio, volume of shale, permeability, and burial history were used to model initial fault transmissibility based on Sperivick model. An improved history match of primary and secondary recovery was performed to set the basis for a CO2 flood study. The performance of the current CO2 miscible flood patterns was subsequently calibrated to historical production and injection data. Several prediction models were constructed to study the effect of recycling, addition of wells and /or new patterns, water alternating gas (WAG) cycles and optimum amount of CO2 purchase on incremental oil production and CO2 storage in the FWU. The history matching study successfully validated the presence of the previously undetected faults within FWU that were seen in the seismic survey. The analysis of the various prediction scenarios showed that recycling a high percentage of produced gas, addition of new wells and a gradual reduction in CO2 purchase after several years of operation would be the best approach to ensure a high percentage of recoverable incremental oil and sequestration of anthropogenic CO2 within the Morrow reservoir. Larger percentage of stored CO2 were dissolved in residual oil and less amount existed as supercritical free CO2. The geomechanical analysis on the caprock proved to an excellent seal to ensure long-term security of injected CO2.

Binary versus non-binary information in real time series: empirical results and maximum-entropy matrix models

NASA Astrophysics Data System (ADS)

Almog, Assaf; Garlaschelli, Diego

2014-09-01

The dynamics of complex systems, from financial markets to the brain, can be monitored in terms of multiple time series of activity of the constituent units, such as stocks or neurons, respectively. While the main focus of time series analysis is on the magnitude of temporal increments, a significant piece of information is encoded into the binary projection (i.e. the sign) of such increments. In this paper we provide further evidence of this by showing strong nonlinear relations between binary and non-binary properties of financial time series. These relations are a novel quantification of the fact that extreme price increments occur more often when most stocks move in the same direction. We then introduce an information-theoretic approach to the analysis of the binary signature of single and multiple time series. Through the definition of maximum-entropy ensembles of binary matrices and their mapping to spin models in statistical physics, we quantify the information encoded into the simplest binary properties of real time series and identify the most informative property given a set of measurements. Our formalism is able to accurately replicate, and mathematically characterize, the observed binary/non-binary relations. We also obtain a phase diagram allowing us to identify, based only on the instantaneous aggregate return of a set of multiple time series, a regime where the so-called ‘market mode’ has an optimal interpretation in terms of collective (endogenous) effects, a regime where it is parsimoniously explained by pure noise, and a regime where it can be regarded as a combination of endogenous and exogenous factors. Our approach allows us to connect spin models, simple stochastic processes, and ensembles of time series inferred from partial information.

Limits to Bureaucratic Growth: The Density Dependence of Organizational Rule Births.

ERIC Educational Resources Information Center

Schulz, Martin

1998-01-01

Uses a population-ecology approach to examine whether bureaucratic rules breed more rules. Tests hypotheses about rule births with time-series data on rule production in a large United States research university. Results show that the rate of rule production declines with the number of rules in a rule population over time. Rules inhibit…

33 CFR 90.3 - Pushing vessel and vessel being pushed: Composite unit.

Code of Federal Regulations, 2010 CFR

2010-07-01

... pushed: Composite unit. 90.3 Section 90.3 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... vessel being pushed: Composite unit. Rule 24(b) of the Inland Rules states that when a pushing vessel and a vessel being pushed ahead are rigidly connected in a composite unit, they are regarded as a power...

40 CFR 60.2770 - What information must I include in my annual report?

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule... calibration drift specification in the applicable performance specification or in the relevant standard. (2...

40 CFR 60.2775 - What else must I report if I have a deviation from the operating limits or the emission limitations?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR... Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2775 What else must I report if I...

40 CFR 60.2775 - What else must I report if I have a deviation from the operating limits or the emission limitations?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR... Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2775 What else must I report if I...

40 CFR 60.2770 - What information must I include in my annual report?

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule... calibration drift specification in the applicable performance specification or in the relevant standard. (2...

Integrating Incremental Learning and Episodic Memory Models of the Hippocampal Region

ERIC Educational Resources Information Center

Meeter, M.; Myers, C. E.; Gluck, M. A.

2005-01-01

By integrating previous computational models of corticohippocampal function, the authors develop and test a unified theory of the neural substrates of familiarity, recollection, and classical conditioning. This approach integrates models from 2 traditions of hippocampal modeling, those of episodic memory and incremental learning, by drawing on an…

On the Accuracy and Parallelism of GPGPU-Powered Incremental Clustering Algorithms.

PubMed

Chen, Chunlei; He, Li; Zhang, Huixiang; Zheng, Hao; Wang, Lei

2017-01-01

Incremental clustering algorithms play a vital role in various applications such as massive data analysis and real-time data processing. Typical application scenarios of incremental clustering raise high demand on computing power of the hardware platform. Parallel computing is a common solution to meet this demand. Moreover, General Purpose Graphic Processing Unit (GPGPU) is a promising parallel computing device. Nevertheless, the incremental clustering algorithm is facing a dilemma between clustering accuracy and parallelism when they are powered by GPGPU. We formally analyzed the cause of this dilemma. First, we formalized concepts relevant to incremental clustering like evolving granularity. Second, we formally proved two theorems. The first theorem proves the relation between clustering accuracy and evolving granularity. Additionally, this theorem analyzes the upper and lower bounds of different-to-same mis-affiliation. Fewer occurrences of such mis-affiliation mean higher accuracy. The second theorem reveals the relation between parallelism and evolving granularity. Smaller work-depth means superior parallelism. Through the proofs, we conclude that accuracy of an incremental clustering algorithm is negatively related to evolving granularity while parallelism is positively related to the granularity. Thus the contradictory relations cause the dilemma. Finally, we validated the relations through a demo algorithm. Experiment results verified theoretical conclusions.

The Milieu Manager: A Nursing Staffing Strategy to Reduce Observer Use in the Acute Psychiatric Inpatient Setting.

PubMed

Triplett, Patrick; Dearholt, Sandra; Cooper, Mary; Herzke, John; Johnson, Erin; Parks, Joyce; Sullivan, Patricia; Taylor, Karin F; Rohde, Judith

Rising acuity levels in inpatient settings have led to growing reliance on observers and increased the cost of care. Minimizing use of observers, maintaining quality and safety of care, and improving bed access, without increasing cost. Nursing staff on two inpatient psychiatric units at an academic medical center pilot-tested the use of a "milieu manager" to address rising patient acuity and growing reliance on observers. Nursing cost, occupancy, discharge volume, unit closures, observer expense, and incremental nursing costs were tracked. Staff satisfaction and reported patient behavioral/safety events were assessed. The pilot initiatives ran for 8 months. Unit/bed closures fell to zero on both units. Occupancy, patient days, and discharges increased. Incremental nursing cost was offset by reduction in observer expense and by revenue from increases in occupancy and patient days. Staff work satisfaction improved and measures of patient safety were unchanged. The intervention was effective in reducing observation expense and improved occupancy and patient days while maintaining patient safety, representing a cost-effective and safe approach for management of acuity on inpatient psychiatric units.

Fuzzy multiobjective models for optimal operation of a hydropower system

NASA Astrophysics Data System (ADS)

Teegavarapu, Ramesh S. V.; Ferreira, André R.; Simonovic, Slobodan P.

2013-06-01

Optimal operation models for a hydropower system using new fuzzy multiobjective mathematical programming models are developed and evaluated in this study. The models use (i) mixed integer nonlinear programming (MINLP) with binary variables and (ii) integrate a new turbine unit commitment formulation along with water quality constraints used for evaluation of reservoir downstream impairment. Reardon method used in solution of genetic algorithm optimization problems forms the basis for development of a new fuzzy multiobjective hydropower system optimization model with creation of Reardon type fuzzy membership functions. The models are applied to a real-life hydropower reservoir system in Brazil. Genetic Algorithms (GAs) are used to (i) solve the optimization formulations to avoid computational intractability and combinatorial problems associated with binary variables in unit commitment, (ii) efficiently address Reardon method formulations, and (iii) deal with local optimal solutions obtained from the use of traditional gradient-based solvers. Decision maker's preferences are incorporated within fuzzy mathematical programming formulations to obtain compromise operating rules for a multiobjective reservoir operation problem dominated by conflicting goals of energy production, water quality and conservation releases. Results provide insight into compromise operation rules obtained using the new Reardon fuzzy multiobjective optimization framework and confirm its applicability to a variety of multiobjective water resources problems.

76 FR 53763 - Immigration Benefits Business Transformation, Increment I

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-29

...The Department of Homeland Security (DHS) is amending its regulations to enable U.S. Citizenship and Immigration Services (USCIS) to migrate from a paper file-based, non-integrated systems environment to an electronic customer-focused, centralized case management environment for benefit processing. This transformation process will allow USCIS to streamline benefit processing, eliminate the capture and processing of redundant data, and reduce the number of and automate its forms. This transformation process will be a phased multi-year initiative to restructure USCIS business processes and related information technology systems. DHS is removing references to form numbers, form titles, expired regulatory provisions, and descriptions of internal procedures, many of which will change during transformation. DHS is also finalizing interim rules that permitted submission of benefit requests with an electronic signature when such requests are submitted in an electronic format rather than on a paper form and that removed references to filing locations for immigration benefits. In addition, in this rule DHS is publishing the final rule for six other interim rules published during the past several years, most of which received no public comments.

40 CFR Table 3 to Subpart Ffff of... - Model Rule-Operating Limits for Incinerators and Wet Scrubbers

Code of Federal Regulations, 2010 CFR

2010-07-01

... Incinerators and Wet Scrubbers 3 Table 3 to Subpart FFFF of Part 60 Protection of Environment ENVIRONMENTAL...—Model Rule—Operating Limits for Incinerators and Wet Scrubbers As stated in § 60.3023, you must comply... units. a 2. Pressure drop across the wet scrubber or amperage to wet scrubber Minimum pressure drop or...

40 CFR Table 3 to Subpart Ffff of... - Model Rule-Operating Limits for Incinerators and Wet Scrubbers

Code of Federal Regulations, 2011 CFR

2011-07-01

... Incinerators and Wet Scrubbers 3 Table 3 to Subpart FFFF of Part 60 Protection of Environment ENVIRONMENTAL...—Model Rule—Operating Limits for Incinerators and Wet Scrubbers As stated in § 60.3023, you must comply... units. a 2. Pressure drop across the wet scrubber or amperage to wet scrubber Minimum pressure drop or...

Microeconomics of process control in semiconductor manufacturing

NASA Astrophysics Data System (ADS)

Monahan, Kevin M.

2003-06-01

Process window control enables accelerated design-rule shrinks for both logic and memory manufacturers, but simple microeconomic models that directly link the effects of process window control to maximum profitability are rare. In this work, we derive these links using a simplified model for the maximum rate of profit generated by the semiconductor manufacturing process. We show that the ability of process window control to achieve these economic objectives may be limited by variability in the larger manufacturing context, including measurement delays and process variation at the lot, wafer, x-wafer, x-field, and x-chip levels. We conclude that x-wafer and x-field CD control strategies will be critical enablers of density, performance and optimum profitability at the 90 and 65nm technology nodes. These analyses correlate well with actual factory data and often identify millions of dollars in potential incremental revenue and cost savings. As an example, we show that a scatterometry-based CD Process Window Monitor is an economically justified, enabling technology for the 65nm node.