Sample records for university barrel array

  1. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    Four reindeer walk past the BARREL payload on the launch pad at Esrange Space Center near Kiruna, Sweden. The BARREL team is at Esrange Space Center launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Image credit: NASA/University of Houston/Samar Mathur NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  2. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    The fourth BARREL balloon of this campaign sits on the launch pad shortly before it launched on Aug. 21, 2016. The BARREL team is at Esrange Space Center near Kiruna, Sweden, launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/University of Houston/Michael Greer NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  3. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    The third BARREL balloon floats towards the stratosphere on Aug. 21, 2016. This payload flew for nearly 30 hours, measuring X-rays in Earth’s atmosphere. The BARREL team is at Esrange Space Center near Kiruna, Sweden, launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/University of Houston/Michael Greer NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  4. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    A BARREL payload sits on the launch pad at Esrange Space Center near Kiruna, Sweden. The BARREL team is at Esrange Space Center launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Image credit: NASA/University of Houston/Edgar Bering NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  5. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    A BARREL team member recovers the second payload after it landed. The BARREL team is at Esrange Space Center near Kiruna, Sweden, launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Image credit: NASA/Montana State University/Arlo Johnson NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  6. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    The BARREL team prepares to launch their third payload from Esrange Space Center near Kiruna, Sweden, on Aug. 21, 2016. The BARREL team is at Esrange Space Center launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/University of Houston/Michael Greer NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  7. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    The first BARREL balloon is inflated just before its launch on Aug. 13, 2016, from Esrange Space Center near Kiruna, Sweden. The BARREL team is at Esrange Space Center launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Image credit: NASA/University of Houston/Edgar Bering NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  8. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    The BARREL team inflates the balloon to launch their fifth scientific payload from Esrange Space Center near Kiruna, Sweden, on Aug. 24, 2016. The BARREL team is at Esrange Space Center launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/University of Houston/Michael Greer NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  9. IMG_4293

    NASA Image and Video Library

    2015-08-14

    The BARREL team prepares to release the second scientific balloon in its Sweden campaign on Aug. 13, 2015. In addition to the instruments used in previous BARREL campaigns, this second balloon launched from the Esrange Space Center in Kiruna is carrying one of two instruments designed by a team from the University of Houston. With funding from the Undergraduate Student Instrument Program, or USIP, at NASA Goddard Space Flight Center’s Wallops Flight Facility, the team of 12 students, under the direction of Edgar Bering at the University of Houston, developed a magnetometer -- which measures magnetic fields -- and an instrument to measure electrons, which flew on this launch. To collect their data, the University of Houston team needs to recover their instrument after the balloon comes down. After this launch, the balloon began to drift toward the mountains, which would have impeded recovery. So the team terminated the flight at 1:18 pm EDT to bring the payload slowly and safely to the ground. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – measures electrons in the atmosphere near the poles. Such electrons rain down into the atmosphere from two giant radiation belts surrounding Earth, called the Van Allen belts. For its third campaign, BARREL is launching six balloons from the Esrange Space Center in Kiruna, Sweden. BARREL is led by Dartmouth College in Hanover, New Hampshire. Credit: NASA/University of Houston/Edgar Bering NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  10. IMG_4999

    NASA Image and Video Library

    2017-12-08

    The BARREL team inflates their second balloon just before its launch on Aug. 13, 2015, from Kiruna, Sweden. The day before this launch, the BARREL team successfully recovered the payload from the first balloon launch on Aug. 10. Payload recovery is especially important for this second launch, which carries an instrument and recorded data from a University of Houston team of student scientists. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – measures electrons in the atmosphere near the poles. Such electrons rain down into the atmosphere from two giant radiation belts surrounding Earth, called the Van Allen belts. For its third campaign, BARREL is launching six balloons from the Esrange Space Center in Kiruna, Sweden. BARREL is led by Dartmouth College in Hanover, New Hampshire. Credit: NASA/Dartmouth/Alexa Halford NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  11. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    The faint green glow of aurora can be seen above the clouds at Esrange Space Center in this photo from Aug. 23, 2016. Auroras are created by energetic electrons, which rain down from Earth’s magnetic bubble and interact with particles in the upper atmosphere to create glowing lights that stretch across the sky. The BARREL team is at Esrange Space Center near Kiruna, Sweden, launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/University of Houston/Michael Greer NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  12. Tapered laser rods as a means of minimizing the path length of trapped barrel mode rays

    DOEpatents

    Beach, Raymond J.; Honea, Eric C.; Payne, Stephen A.; Mercer, Ian; Perry, Michael D.

    2005-08-30

    By tapering the diameter of a flanged barrel laser rod over its length, the maximum trapped path length of a barrel mode can be dramatically reduced, thereby reducing the ability of the trapped spontaneous emission to negatively impact laser performance through amplified spontaneous emission (ASE). Laser rods with polished barrels and flanged end caps have found increasing application in diode array end-pumped laser systems. The polished barrel of the rod serves to confine diode array pump light within the rod. In systems utilizing an end-pumping geometry and such polished barrel laser rods, the pump light that is introduced into one or both ends of the laser rod, is ducted down the length of the rod via the total internal reflections (TIRs) that occur when the light strikes the rod's barrel. A disadvantage of using polished barrel laser rods is that such rods are very susceptible to barrel mode paths that can trap spontaneous emission over long path lengths. This trapped spontaneous emission can then be amplified through stimulated emission resulting in a situation where the stored energy available to the desired lasing mode is effectively depleted, which then negatively impacts the laser's performance, a result that is effectively reduced by introducing a taper onto the laser rod.

  13. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    A member of the BARREL team prepares a payload for launch from Esrange Space Center on Aug. 29, 2016. Throughout August 2016, the BARREL team was at Esrange Space Center near Kiruna, Sweden, launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carried instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/Dartmouth/Alexa Halford NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  14. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    Prior to launch, the BARREL team works on the payload from the launch pad at Esrange Space Center near Kiruna, Sweden. The BARREL team is at Esrange Space Center launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Image credit: NASA/Dartmouth/Robyn Millan NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  15. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    A BARREL team member watches as one of their payloads launches from Esrange Space Center on Aug. 29, 2016. Throughout August 2016, the BARREL team was at Esrange Space Center near Kiruna, Sweden, launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carried instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/Dartmouth/Alexa Halford NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  16. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    A BARREL balloon inflates on the launch pad at Esrange Space Center on Aug. 29, 2016. Throughout August 2016, the BARREL team was at Esrange Space Center near Kiruna, Sweden, launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carried instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Credit: NASA/Dartmouth/Alexa Halford NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  17. NASA's BARREL Mission in Sweden

    NASA Image and Video Library

    2017-12-08

    A BARREL payload sits on the launch pad at Esrange Space Center near Kiruna, Sweden. The BARREL team is at Esrange Space Center launching a series of six scientific payloads on miniature scientific balloons. The NASA-funded BARREL – which stands for Balloon Array for Radiation-belt Relativistic Electron Losses – primarily measures X-rays in Earth’s atmosphere near the North and South Poles. These X-rays are produced by electrons raining down into the atmosphere from two giant swaths of radiation that surround Earth, called the Van Allen belts. Learning about the radiation near Earth helps us to better protect our satellites. Several of the BARREL balloons also carry instruments built by undergraduate students to measure the total electron content of Earth’s ionosphere, as well as the low-frequency electromagnetic waves that help to scatter electrons into Earth’s atmosphere. Though about 90 feet in diameter, the BARREL balloons are much smaller than standard football stadium-sized scientific balloons. This is the fourth campaign for the BARREL mission. BARREL is led by Dartmouth College in Hanover, New Hampshire. The undergraduate student instrument team is led by the University of Houston and funded by the Undergraduate Student Instrument Project out of NASA’s Wallops Flight Facility. For more information on NASA’s scientific balloon program, visit: www.nasa.gov/scientificballoons. Image credit: NASA/Dartmouth/Robyn Millan NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  18. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2017-12-08

    Researchers communicate with the BARREL ground station during preparations for launch. The white box in the background is the science payload and the orange and white parachute can be seen on the ground in front of it. On the left is BARREL Principal Investigator Robyn Millan of Dartmouth College in Hanover, N.H.; on the right is BARREL Co-Investigator Michael McCarthy of the University of Washington in Seattle. Credit: NASA/Goddard/BARREL/M. Krzysztofowicz Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  19. First data with the Hybrid Array of Gamma Ray Detector (HAGRiD)

    NASA Astrophysics Data System (ADS)

    Smith, K.; Baugher, T.; Burcher, S.; Carter, A. B.; Cizewski, J. A.; Chipps, K. A.; Febbraro, M.; Grzywacz, R.; Jones, K. L.; Munoz, S.; Pain, S. D.; Paulauskas, S. V.; Ratkiewicz, A.; Schmitt, K. T.; Thornsberry, C.; Toomey, R.; Walter, D.; Willoughby, H.

    2018-01-01

    The structure of nuclei provides insight into astrophysical reaction rates that are difficult to measure directly. These studies are often performed with transfer reactions and β-decay measurements. These experiments benefit from particle-γ coincidence measurements which provide information beyond that of particle detection alone. The Hybrid Array of Gamma Ray Detectors (HAGRiD) of LaBr3(Ce) scintillators has been designed with this purpose in mind. The design of the array permits it to be coupled with particle detector systems, such as the Oak Ridge Rutgers University Barrel Array (ORRUBA) of silicon detectors and the Versatile Array of Neutron Detectors at Low Energy (VANDLE). It is also designed to operate with the Jet Experiments in Nuclear Structure and Astrophysics (JENSA) advanced target system. HAGRiD's design avoids compromising the charged-particle angular resolution due to compact geometries which are often used to increase the γ efficiency in other systems. First experiments with HAGRiD coupled to VANDLE as well as ORRUBA and JENSA are discussed.

  20. Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography

    PubMed Central

    Weiler, Nicholas C; Collman, Forrest; Vogelstein, Joshua T; Burns, Randal; Smith, Stephen J

    2014-01-01

    A major question in neuroscience is how diverse subsets of synaptic connections in neural circuits are affected by experience dependent plasticity to form the basis for behavioral learning and memory. Differences in protein expression patterns at individual synapses could constitute a key to understanding both synaptic diversity and the effects of plasticity at different synapse populations. Our approach to this question leverages the immunohistochemical multiplexing capability of array tomography (ATomo) and the columnar organization of mouse barrel cortex to create a dataset comprising high resolution volumetric images of spared and deprived cortical whisker barrels stained for over a dozen synaptic molecules each. These dataset has been made available through the Open Connectome Project for interactive online viewing, and may also be downloaded for offline analysis using web, Matlab, and other interfaces. PMID:25977797

  1. Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography.

    PubMed

    Weiler, Nicholas C; Collman, Forrest; Vogelstein, Joshua T; Burns, Randal; Smith, Stephen J

    2014-01-01

    A major question in neuroscience is how diverse subsets of synaptic connections in neural circuits are affected by experience dependent plasticity to form the basis for behavioral learning and memory. Differences in protein expression patterns at individual synapses could constitute a key to understanding both synaptic diversity and the effects of plasticity at different synapse populations. Our approach to this question leverages the immunohistochemical multiplexing capability of array tomography (ATomo) and the columnar organization of mouse barrel cortex to create a dataset comprising high resolution volumetric images of spared and deprived cortical whisker barrels stained for over a dozen synaptic molecules each. These dataset has been made available through the Open Connectome Project for interactive online viewing, and may also be downloaded for offline analysis using web, Matlab, and other interfaces.

  2. An evaluation of the conductivity profile in the somatosensory barrel cortex of Wistar rats.

    PubMed

    Goto, Takakuni; Hatanaka, Rieko; Ogawa, Takeshi; Sumiyoshi, Akira; Riera, Jorge; Kawashima, Ryuta

    2010-12-01

    Microelectrode arrays used to record local field potentials from the brain are being built with increasingly more spatial resolution, ranging from the initially developed laminar arrays to those with planar and three-dimensional (3D) formats. In parallel with such development in recording techniques, current source density (CSD) analyses have recently been expanded up to the continuous-3D form. Unfortunately, the effect of the conductivity profile on the CSD analysis performed with contemporary microelectrode arrays has not yet been evaluated and most of the studies assumed it was homogeneous and isotropic. In this study, we measured the conductivity profile in the somatosensory barrel cortex of Wistar rats. To that end, we combined multisite electrophysiological data recorded with a homemade assembly of silicon-based probes and a nonlinear least-squares algorithm that implicitly assumed that the cerebral cortex of rodents could be locally approximated as a layered anisotropic spherical volume conductor. The eccentricity of the six cortical layers in the somatosensory barrel cortex was evaluated from postmortem histological images. We provided evidence for the local spherical character of the entire barrels field, with concentric cortical layers. We found significant laminar dependencies in the conductivity values with radial/tangential anisotropies. These results were in agreement with the layer-dependent orientations of myelinated axons, but hardly related to densities of cells. Finally, we demonstrated through simulations that ignoring the real conductivity profile in the somatosensory barrel cortex of rats caused considerable errors in the CSD reconstruction, with pronounced effects on the continuous-3D form and charge-unbalanced CSD. We concluded that the conductivity profile must be included in future developments of CSD analysis, especially for rodents.

  3. The Undergraduate Student Instrumentation Projects at the University of Houston

    NASA Astrophysics Data System (ADS)

    Bering, E. A., III; Talbot, R. W.; Glennie, C. L.; Rodrigues, D.; Jinghong, C.; Alozie, M.; Behrend, C. C.; Bias, C.; Ehteshami, A.; Fenton, A.; Greer, M.; Gunawan, B.; Harrison, W.; Jordan, J.; Lalata, M. C.; Lehnen, J. N.; Martinez, A.; Mathur, S.; Medillin, M.; Nguyen, T.; Nguyen, T. V.; Nowling, M.; Perez, D.; Pham, M.; Pina, M.; Porat, I.; Prince, J.; Thomas, G. C.; Velasquez, B.; Victor, L.

    2016-12-01

    The Undergraduate Student Instrumentation Project (USIP) is a NASA program to engage undergraduate students in rigorous scientific research, for the purposes of innovation and developing the next generation of professionals for an array of fields. The program is student led and executed from initial ideation to research to the design and deployment of scientific payloads. The University of Houston has been selected twice to participate in the USIP programs. The first program (USIP_UH I) ran from 2013 to 2016. USIP_UH II started in January of this year, with funding starting at the end of May. USIP_UH I (USIP_UH II) at the University of Houston was (is) composed of eight (seven) research teams developing six (seven), distinct, balloon-based scientific instruments. These instruments will contribute to a broad range of geophysical sciences from Very Low Frequency recording and Total Electron Content to exobiology and ozone profiling. USIP_UH I had 12 successful launches with 9 recoveries from Fairbanks, AK in March 2015 and 4 piggyback flights with BARREL 3 from Esrange, Kiruna, Sweden in August, 2015. Additional flights with BARREL 4 will take place in August 2016. The great opportunity of this program is capitalizing on the proliferation of electronics miniaturization to create new generations of scientific instruments that are smaller and lighter than ever before. This situation allows experiments to be done more cheaply which ultimately allows many more experiments to be done.

  4. University of Houston Undergraduate Student Instrumentation Projects

    NASA Astrophysics Data System (ADS)

    Bering, E. A., III; Talbot, R. W.; Hampton, D. L.; Molders, N.; Millan, R. M.; Halford, A. J.; Dunbar, B.; Morris, G. A.; Prince, J.; Gamblin, R.; Ehteshami, A.; Lehnen, J. N.; Greer, M.; Porat, I.; Alozie, M.; Behrend, C. C.; Bias, C.; Fenton, A.; Gunawan, B.; Harrison, W.; Martinez, A.; Mathur, S.; Medillin, M.; Nguyen, T.; Nguyen, T. V.; Nowling, M.; Perez, D.; Pham, M.; Pina, M.; Thomas, G.; Velasquez, B.; Victor, L.

    2017-12-01

    The Undergraduate Student Instrumentation Project (USIP) is a NASA program to engage undergraduate students in rigorous scientific research, for the purposes of innovation and developing the next generation of professionals for an array of fields. The program is student led and executed from initial ideation to research to the design and deployment of scientific payloads. The University of Houston has been selected twice to participate in the USIP programs. The first program (USIP_UH I) ran from 2013 to 2016. USIP_UH II started in January of 2016, with funding starting at the end of May. USIP_UH I (USIP_UH II) at the University of Houston was (is) composed of eight (seven) research teams developing six (seven), distinct, balloon-based scientific instruments. These instruments will contribute to a broad range of geophysical sciences from Very Low Frequency recording and Total Electron Content to exobiology and ozone profiling. USIP_UH I had 12 successful launches with 9 recoveries from Fairbanks, AK in March 2015, and 4 piggyback flights with BARREL 3 from Esrange, Kiruna, Sweden in August, 2015. USIP_UH II had 8 successful launches with 5 recoveries from Fairbanks, AK in March 2017, 3 piggyback flights with BARREL 4 from Esrange, Kiruna, Sweden in August, 2016, and 1 flight each from CSBF and UH. The great opportunity of this program is capitalizing on the proliferation of electronics miniaturization to create new generations of scientific instruments that are smaller and lighter than ever before. This situation allows experiments to be done more cheaply which ultimately allows many more experiments to be done.

  5. R&D of a High-Performance DIRC Detector for a Future Electron-Ion Collider

    NASA Astrophysics Data System (ADS)

    Allison, Stacey Lee

    An Electron-Ion Collider (EIC) is proposed as the next big scientific facility to be built in the United States, costing over $1 billion in design and construction. Each detector concept for the electron/ion beam interaction point is integrated into a large solenoidal magnet. The necessity for excellent hadronic particle identification (pion/kaon/proton) in the barrel region of the solenoid has pushed research and development (R&D) towards a new, high-performance Detection of Internally Reflected Cherenkov light (DIRC) detector design. The passage of a high energy charged particle through a fused silica bar of the DIRC generates optical Cherenkov radiation. A large fraction of this light propagates by total internal reflection to the end of the bar, where the photon trajectories expand in a large volume before reaching a highly segmented photo-detector array. The spatial and temporal distribution of the Cherenkov light at the photo-detector array allows one to reconstruct the angle of emission of the light relative to the incident charged particle track. In order to reach the desired performance of 3sigma pi/K separation at 6 GeV/c particle momentum a new 3-layer spherical lens focusing optic with a lanthanum crown glass central layer was designed to have a nearly flat focal plane. In order to validate the EIC DIRC simulation package, a synergistic test beam campaign was carried out in 2015 at the CERN PS with the PANDA Barrel DIRC group using a prototype DIRC detector. Along with the analysis of the CERN test beam data, measurements of the focal plane of the 3-layer lens were performed using a custom-built laser setup at Old Dominion University. Radiation hardness of the lanthanum crown glass was tested using a 160 keV X-ray source and a monochromator at the Catholic University of America. Results of these test-bench experiments and the analysis of the 2015 CERN test beam data are presented here.

  6. R&D of a high-performance DIRC detector for a future electron-ion collider

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allison, Staceu L.

    An Electron-Ion Collider (EIC) is proposed as the next big scientific facility to be built in the United States, costing over $1 billion in design and construction. Each detector concept for the electron/ion beam interaction point is integrated into a large solenoidal magnet. The necessity for excellent hadronic particle identification (pion/kaon/proton) in the barrel region of the solenoid has pushed research and development (R&D) towards a new, high-performance Detection of Internally Reflected Cherenkov light (DIRC) detector design. The passage of a high energy charged particle through a fused silica bar of the DIRC generates optical Cherenkov radiation. A large fractionmore » of this light propagates by total internal reflection to the end of the bar, where the photon trajectories expand in a large volume before reaching a highly segmented photo-detector array. The spatial and temporal distribution of the Cherenkov light at the photo-detector array allows one to reconstruct the angle of emission of the light relative to the incident charged particle track. In order to reach the desired performance of 3sigma pi/K separation at 6 GeV/c particle momentum a new 3-layer spherical lens focusing optic with a lanthanum crown glass central layer was designed to have a nearly at focal plane. In order to validate the EIC DIRC simulation package, a synergistic test beam campaign was carried out in 2015 at the CERN PS with the PANDA Barrel DIRC group using a prototype DIRC detector. Along with the analysis of the CERN test beam data, measurements of the focal plane of the 3-layer lens were performed using a custom-built laser setup at Old Dominion University. Radiation hardness of the lanthanum crown glass was tested using a 160 keV X-ray source and a monochromator at the Catholic University of America. Results of these test-bench experiments and the analysis of the 2015 CERN test beam data are presented here.« less

  7. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2017-12-08

    The Halley station team members assisted the BARREL team with the launches. Here, one gives the thumbs up to start inflating a BARREL balloon. Credit: NASA/Goddard/BARREL/M. Krzysztofowicz Read more: www.nasa.gov/content/nasas-barrel-returns-successful-from... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  8. Twenty years of barrel-stave flextensional transducer technology in Canada

    NASA Astrophysics Data System (ADS)

    Jones, Dennis F.

    2005-04-01

    The barrel-stave flextensional transducer, a compact underwater sound source, was conceived at DRDC Atlantic in 1986 [G. W. McMahon and D. F. Jones, U.S. Patent No. 4,922,470 (1 May 1990); Canadian Patent No. 1,285,646 (2 July 1991)]. Over the years, five barrel-stave designs belonging to three flextensional classes were built and tested at DRDC Atlantic. Three Class I transducers with operating frequencies ranging from 800 to 1600 Hz were integrated into submarine communications buoys, low frequency active horizontal projector arrays, and a broadband sonar towbody. A high-power Class II and broadband (1-7 kHz) Class III transducer were deployed under the ice in the Lincoln Sea for research related to rapidly deployable surveillance systems. These barrel-stave flextensional transducers have also supported a variety of marine mammal studies including vocal mimicry in long-finned pilot whales, coda dialects in sperm whales, and the R&D of acoustic detection and tracking systems for endangered northern right whales. In August 2004 a barrel-stave transducer was used to lure a trapped juvenile humpback whale to the sluice gates of a tidal generating station on the Annapolis River in Nova Scotia by transmitting humpback whale calls underwater. The acoustic performance parameters for all 5 transducers will be presented.

  9. Effect of Barrel Material on Critical Current Measurements of High-Jc RRP Nb3Sn Wires

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ghosh, A.

    Nb{sub 3}Sn strands extracted from a 20-strand rectangular Rutherford cable were reacted on either stainless steel or Ti-alloy barrels and the critical current, I{sub c}, in the field range of 8-11.5 T was measured on ITER-type barrels made from Ti-6Al-4V alloy, 304 stainless steel and G-10. Measurements on the 'standard' Ti-alloy barrel using the test procedure employed at BNL are shown to reproduce I{sub c} for extracted strands to {+-}2%. The I{sub c} data for the sample mounted on the 'standard' Ti-alloy are fit to the deviatoric strain scaling model developed for Nb{sub 3}Sn by the University of Twente groupmore » using an arbitrary pre-strain. Using the parameters for this fit, the I{sub c} data for the other barrels are fitted by only adjusting the strain. Using this procedure, the strain difference due to the barrel material is determined. Assuming a thermal pre-strain of -0.2% for the sample measured on the Ti-alloy barrel, the use of stainless steel barrel increases the compressive strain by -0.07%, that of G-10 by -0.10%. With the wire soldered to the stainless steel barrel, the strain increases to -0.15%. Details of this study are presented.« less

  10. Developing the (d,p γ) reaction as a surrogate for (n, γ) in inverse kinematics

    NASA Astrophysics Data System (ADS)

    Lepailleur, Alexandre; Baugher, Travis; Cizewski, Jolie; Ratkiewicz, Andrew; Walter, David; Pain, Steven; Smith, Karl; Garland, Heather; Goddess Collaboration

    2016-09-01

    The r-process that proceeds via (n, γ) reactions on neutron-rich nuclei is responsible for the synthesis of about half of the elements heavier than iron. Because (n, γ) measurements on short-lived isotopes are not possible, the (d,p γ) reaction is being investigated as a surrogate for (n, γ). Of particular importance is validating a surrogate in inverse kinematics. Therefore, the 95Mo(d,p γ) reaction was measured in inverse kinematics with stable beams from ATLAS and CD2 targets. Reaction protons were measured in coincidence with gamma rays with GODDESS - Gammasphere ORRUBA: Dual Detectors for Experimental Structure Studies. The Oak Ridge Rutgers University Barrel Array (ORRUBA) of position-sensitive silicon strip detectors was augmented with annular arrays of segmented strip detectors at backward and forward angles, resulting in a high-angular coverage for light ejectiles. Preliminary results from the 95Mo(d,p γ) study will be presented. This work was supported in part by the U.S. Department of Energy and National Science Foundation.

  11. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    BARREL team members lift up the instrument box below an inflated BARREL balloon to help with launch. Credit: NASA/Goddard/Francois Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy.NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission.Follow us on TwitterLike us on FacebookFind us on Instagram

  12. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    Recovery of a BARREL balloon payload after its flight. The recovery was carried out by helicopter. This area is known to be heavily crevassed so the base mountaineer is seen here with a safety rope. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  13. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    While large compared to a human, BARREL balloons are actually much smaller than typical science balloons, which can be as large as a football field. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  14. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    A BARREL balloon launches up into the sky, destined to float on the circumpolar winds around the South Pole for up to three weeks while measuring Earth's magnetic field and energetic particles from the radiation belts. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  15. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2017-12-08

    The BARREL team at Halley Research Station in Antarctica, work to inflate a balloon. The long tube on the left is the inflation tube used to fill the top of the balloon with helium. Credit: NASA/Goddard/BARREL Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy.NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission.Follow us on TwitterLike us on FacebookFind us on Instagram

  16. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2017-12-08

    Members of the BARREL team in Antarctica jump up and down in what they call the Low Wind Dance as they hope for the low wind conditions needed to launch another balloon. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  17. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2017-12-08

    BARREL researchers get ready to release the top part of the balloon, called the bubble, as it fills with enough helium to support itself. Only the top part of the balloon is inflated before launch since the helium expands as the balloon ascends. Credit: NASA/Goddard/BARREL/Nicky Knox Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  18. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    The BARREL team at the South African research station, SANAE IV, poses next to the instrument box, which will float in the atmosphere beneath the balloon that can be seen being inflated in the background. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  19. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    The BARREL team at the South African research station, SANAE IV, lay out the 130-foot-long balloon on the ground to prepare for inflation. The entire set up and launch process takes three to four hours. Credit: NASA/Goddard/BARREL/Nicky Knox Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  20. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    Release of a BARREL balloon. The launch crew can be seen on the right holding the payload as the top of the balloon moves overhead where they can release it. Credit: NASA/Goddard/BARREL Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy.NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission.Follow us on TwitterLike us on FacebookFind us on Instagram

  1. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    Getting fuller! A BARREL balloon is filled with helium during the 2013-2014 mission campaign in Antarctica. Credit: NASA/Goddard/BARREL Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy.NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission.Follow us on TwitterLike us on FacebookFind us on Instagram

  2. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    The BARREL instrument in Antarctica– prior to being encased in its protective box – destined to float beneath a giant balloon to study magnetic fields and energetic particles near the South Pole. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  3. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    Getting ready to lay out a BARREL balloon to prepare for inflation. The helium stillages used to fill the balloon can be seen in the background. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  4. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    A team member from South African research station, SANAE IV, helps unwrap the balloon from its protective yellow plastic cover just prior to inflation. Credit: NASA/Goddard/BARREL/Nicky Knox Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  5. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    A group picture of all the researchers – from various science projects -- at the South African research station, SANAE IV, Antarctica, in the (Southern) summer 2013-2014. Credit: NASA/Goddard/BARREL/Brett Anderson Read more: www.nasa.gov/content/nasas-barrel-returns-successful-from... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  6. Ballooning in the constant sun of the South Pole summer

    NASA Image and Video Library

    2014-04-24

    A view looking over the payload – the instruments that fly under a balloon – while the BARREL balloon inflates. The orange parachute lies on the ground in front of the payload, while most of the balloon length can be seen stretched along the ground toward the part being inflated. Credit: NASA/Goddard/BARREL Read more: www.nasa.gov/content/goddard/nasas-barrel-returns-success... -- Three months, 20 balloons, and one very successful campaign. The team for NASA's BARREL – short for Balloon Array for Radiation belt Relativistic Electron Losses -- mission returned from Antarctica in March 2014. BARREL's job is to help unravel the mysterious Van Allen belts, two gigantic donuts of radiation that surround Earth, which can shrink and swell in response to incoming energy and particles from the sun and sometimes expose satellites to harsh radiation. While in Antarctica, the team launched 20 balloons carrying instruments that sense charged particles that are scattered into the atmosphere from the belts, spiraling down the magnetic fields near the South Pole. Each balloon traveled around the pole for up to three weeks. The team will coordinate the BARREL data with observations from NASA's two Van Allen Probes to better understand how occurrences in the belts relate to bursts of particles funneling down toward Earth. BARREL team members will be on hand at the USA Science and Engineering Festival in DC on April 26 and 27, 2014 for the exhibit Space Balloons: Exploring the Extremes of Space Weather. NASA image use policy.NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission.Follow us on TwitterLike us on FacebookFind us on Instagram

  7. Developing the (d,p γ) reaction as a surrogate for (n, γ) in inverse kinematics

    NASA Astrophysics Data System (ADS)

    Lepailleur, Alexandr; Sims, Harry; Garland, Heather; Baugher, Travis; Cizewski, Jolie A.; Ratkiewicz, Andrew; Walter, Daivid; Pain, Steven D.; Smith, Karl; Goddess Collaboration Collaboration

    2017-09-01

    The r-process that proceeds via (n, γ) reactions on neutron-rich nuclei is responsible for the synthesis of about half of the elements heavier than iron. Because (n, γ) measurements on short-lived isotopes are not possible, the (d,p γ) reaction is being investigated as a surrogate for (n, γ) . The experimental setup GODDESS (Gammasphere ORRUBA: Dual Detectors for Experimental Structure Studies) has been developed especially for this purpose. The Oak Ridge Rutgers University Barrel Array (ORRUBA) of position-sensitive silicon strip detectors was augmented with annular arrays of segmented strip detectors at backward and forward angles, resulting in a high-angular coverage for light ejectiles (20 to 160 degrees in the laboratory frame). The 134Xe(d,p γ) reaction, used to commission the setup, was measured in inverse kinematics with stable beams from ATLAS impinged on C2D4 targets. Reaction protons were measured (ORRUBA) in coincidence with gamma rays (Gammasphere). An overview of GODDESS and preliminary results from the 134Xe(d,p γ) study will be presented. Work supported in part by U.S. D.O.E. and National Science Foundation.

  8. Observations of Solar Energetic Protons: A Comparison Between Model, Balloon, and In Situ Observations

    NASA Astrophysics Data System (ADS)

    Halford, A.; Millan, R. M.; Hudson, M. K.; McGregor, S. L.; Kress, B. T.

    2014-12-01

    The Balloon Array for Radiation belt Relativistic Electron Losses (BARREL) was designed to observe X-rays from precipitating electrons in the Earth's atmosphere. During the second campaign in January 2014 Solar Energetic Proton (SEP) events were detected in the BARREL payloads as they produced atmospheric x-rays, γ-rays, and directly injected protons observed by the scintillator on the BARREL payloads. A total of 6 payloads were up during the event beginning 7 January with an X-class flare at 1832 UT, spread across a wide range of L and MLT. Payload 2I was on open field lines for the entire event while 2T (2W) crossed from open (closed) to closed (open) field lines over the course of the three day event. Payloads 2K and 2L were moving from the inner magnetosphere (L ~ 4) to higher field lines (L>6) while 2X stayed within the inner magnetosphere (L<6) for the entire event. Throughout this time, there were multiple conjunctions with the Van Allen Probes and good agreement with when (UT) and where (L-values) the energetic protons were observed, both in situ and at the balloons. In this poster we consider the transport of the protons from the sun and through the magnetosphere and eventual precipitation observed by the BARREL balloons.

  9. Observations of a solar storm from the stratosphere: The BARREL Mission

    NASA Astrophysics Data System (ADS)

    Halford, Alexa

    2016-07-01

    During the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL) second campaign, BARREL observed with a single primary instrument, a 3"x3" NaI spectrometer measuring 20 keV - 10 MeV X-rays [Woodger et al 2015 JGR], portions of an entire solar storm. This very small event, in terms of geomagnetic activity, or one of the largest of the current solar cycle, in terms of solar energetic particle events, has given us a very clear set of observations of the response of the day side magnetosphere to the arrival of an interplanetary coronal mass ejection shock. The BARREL mission of opportunity working in tandem with the Van Allen Probes was designed to study the loss of radiation belt electrons to the ionosphere and upper atmosphere. However BARREL is able to see X-rays from a multitude of sources. During the second campaign, the Sun produced, and BARREL observed, an X-class flare [McGregor et al in prep.]. This was followed by BARREL observations of X-rays, gamma-rays, and directly injected protons from the solar energetic particle (SEP) event associated with the eruption from the Sun while simultaneously the Van Allen Probes observed the SEP protons in the inner magnetosphere [Halford et al 2016 submitted JGR]. Two days later the shock generated by the interplanetary coronal mass ejection (ICME-shock) hit the Earth while BARREL was in conjunction with the Van Allen Probes and GOES [Halford et al 2015 JGR]. Although this was a Mars directed CME and the Earth only received a glancing blow [Möstl et al 2015 Nat. Commun., Mays et al 2015 ApJ], the modest compression led to the formation of ultra low frequency (ULF) waves, electromagnetic ion cyclotron (EMIC) waves, and very low frequency (VLF) whistler mode waves [Halford and Mann 2016 submitted to JGR]. The combination of these waves and the enhancement of the local particle population led to precipitation of electrons remotely observed by BARREL. This was not a Halloween, Bastille Day, or one of the now many St. Patricks Day storms. In fact it's unlikely that it will ever get it's own Holliday nickname. But unlike those larger geomagnetic events, the 7 - 10 January 2014 event was less complicated allowing us to directly test the relative importance of multiple loss mechanisms, see how waves are generated, and by and large gain a more complete understanding of how the system interacts as well as how quiet times can affect radiation belt dynamics.

  10. Results from the USIP_UH contribution to the BARREL-4 campaign

    NASA Astrophysics Data System (ADS)

    Behrend, C. C.; Bering, E. A., III; Ehteshami, A.; Fenton, A.; Gamblin, R.; Greer, M.; Mathur, S.; Glennie, C. L.; Velasquez, B.; Marpaung, J.; Lalata, M. C.

    2016-12-01

    The Undergraduate Student Instrumentation Project (USIP) at the University of Houston sent a team to Kiruna, Sweden to participate with NASA/Dartmouth's BARREL-4 campaign in August 2016. BARREL-4's primary instrument is an MeV x-ray scintillation counter. The team has provided two different experiments to be flown, a dual frequency GPS receiver to calculate total electron content and a Very Low Frequency (VLF) receiver to measure the VLF emissions associated with electron precipitation. TEC is calculated via finding pseudo-ranges comparing the sent and received signals from passing satellites. The VLF receiver has an air-core magnetic loop antenna that utilizes a transformer coupled with an integrating pre-amp which is then recorded to a standard music recorder. The presentation will include a summary of observations.

  11. All-optical mapping of barrel cortex circuits based on simultaneous voltage-sensitive dye imaging and channelrhodopsin-mediated photostimulation

    PubMed Central

    Lo, Shun Qiang; Koh, Dawn X. P.; Sng, Judy C. G.; Augustine, George J.

    2015-01-01

    Abstract. We describe an experimental approach that uses light to both control and detect neuronal activity in mouse barrel cortex slices: blue light patterned by a digital micromirror array system allowed us to photostimulate specific layers and columns, while a red-shifted voltage-sensitive dye was used to map out large-scale circuit activity. We demonstrate that such all-optical mapping can interrogate various circuits in somatosensory cortex by sequentially activating different layers and columns. Further, mapping in slices from whisker-deprived mice demonstrated that chronic sensory deprivation did not significantly alter feedforward inhibition driven by layer 5 pyramidal neurons. Further development of voltage-sensitive optical probes should allow this all-optical mapping approach to become an important and high-throughput tool for mapping circuit interactions in the brain. PMID:26158003

  12. Structure, function, and cortical representation of the rat submandibular whisker trident.

    PubMed

    Thé, Lydia; Wallace, Michael L; Chen, Christopher H; Chorev, Edith; Brecht, Michael

    2013-03-13

    Although the neurobiology of rodent facial whiskers has been studied intensively, little is known about sensing in other vibrissae. Here we describe the under-investigated submandibular "whisker trident" on the rat's chin. In this three-whisker array, a unique unpaired midline whisker is laterally flanked by two slightly shorter whiskers. All three whiskers point to the ground and are curved backwards. Unlike other whiskers, the trident is not located on an exposed body part. Trident vibrissae are not whisked and do not touch anything over long stretches of time. However, trident whiskers engage in sustained ground contact during head-down running while the animal is exploring or foraging. In biomechanical experiments, trident whiskers follow caudal ground movement more smoothly than facial whiskers. Remarkably, deflection angles decrease with increasing ground velocity. We identified one putative trident barrel in the left somatosensory cortex and two barrels in the right somatosensory cortex. The elongated putative trident-midline barrel is the longest and largest whisker barrel, suggesting that the midline trident whisker is of great functional significance. Cortical postsynaptic air-puff responses in the trident representation show much less temporal precision than facial whisker responses. Trident whiskers do not provide as much high-resolution information about object contacts as facial whiskers. Instead, our observations suggest an idiothetic function: their biomechanics allow trident whiskers to derive continuous measurements about ego motion from ground contacts. The midline position offers unique advantages in sensing heading direction in a laterally symmetric manner. The changes in trident deflection angle with velocity suggest that trident whiskers might function as a tactile speedometer.

  13. A wireline piston core barrel for sampling cohesionless sand and gravel below the water table

    USGS Publications Warehouse

    Zapico, Michael M.; Vales, Samuel; Cherry, John A.

    1987-01-01

    A coring device has been developed to obtain long and minimally disturbed samples of saturated cohesionless sand and gravel. The coring device, which includes a wireline and piston, was developed specifically for use during hollow-stem auger drilling but it also offers possibilities for cable tool and rotary drilling. The core barrel consists of an inner liner made of inexpensive aluminum or plastic tubing, a piston for core recovery, and an exterior steel housing that protects the liner when the core barrel is driven into the aquifer. The core barrel, which is approximately 1.6m (5.6 feet) long, is advanced ahead of the lead auger by hammering at the surface on drill rods that are attached to the core barrel. After the sampler has been driven 1.5m (5 feet), the drill rods are detached and a wireline is used to hoist the core barrel, with the sample contained in the aluminum or plastic liner, to the surface. A vacuum developed by the piston during the coring operation provides good recovery of both the sediment and aquifer fluids contained in the sediment. In the field the sample tubes can be easily split along their length for on-site inspection or they can be capped with the pore water fluids inside and transported to the laboratory. The cores are 5cm (2 inches) in diameter by 1.5m (5 feet) long. Core acquisition to depths of 35m (115 feet), with a recovery greater than 90 percent, has become routine in University of Waterloo aquifer studies. A large diameter (12.7cm [5 inch]) version has also been used successfully. Nearly continuous sample sequences from sand and gravel aquifers have been obtained for studies of sedimentology, hydraulic conductivity, hydrogeochemistry and microbiology.

  14. Development of the Off-line Analysis Code for GODDESS

    NASA Astrophysics Data System (ADS)

    Garland, Heather; Cizewski, Jolie; Lepailleur, Alex; Walters, David; Pain, Steve; Smith, Karl

    2016-09-01

    Determining (n, γ) cross sections on unstable nuclei is important for understanding the r-process that is theorized to occur in supernovae and neutron-star mergers. However, (n, γ) reactions are difficult to measure directly because of the short lifetime of the involved neutron rich nuclei. A possible surrogate for the (n, γ) reaction is the (d,p γ) reaction; the measurement of these reactions in inverse kinematics is part of the scope of GODDESS - Gammasphere ORRUBA (Oak Ridge Rutgers University Barrel Array): Dual Detectors for Experimental Structure Studies. The development of an accurate and efficient off-line analysis code for GODDESS experiments is not only essential, but also provides a unique opportunity to create an analysis code designed specifically for transfer reaction experiments. The off-line analysis code has been developed to produce histograms from the binary data file to determine how to best sort events. Recent developments in the off-line analysis code will be presented as well as details on the energy and position calibrations for the ORRUBA detectors. This work is supported in part by the U.S. Department of Energy and National Science Foundation.

  15. Investigation of a playa lake bed using geophysical electrical methods

    NASA Astrophysics Data System (ADS)

    Herrmenn, M.; Gurrola, H.; William, R.; Montalvo, R.; Horton, S.; Homberg, J.; Allen, T.; Bribiesca, E.; Lindsey, C.; Anderson, H.; Seshadri, S.; Manns, S.; Hassan, A.; Loren, C.

    2005-12-01

    The 2005 undergraduate applied geophysical class of Texas Tech University conducted a geophysical survey of a playa lake approximately 10 miles northwest of Lubbock Texas. The playa lake is primarily used as grazing land for two llamas and a hand full of sheep, and has been recently used as a dump for broken down sheds and barrels. Our goal was to model the subsurface of the transition from the playa to plains geology and investigate the possible contamination, of the soil and the data, by the metal dumped at the surface. We conducted our survey with and EM31 and homemade D.C. resistivity and SP equipment that allowed students to grasp the theories more clearly. SP readings were collected using clay pots constructed from terracotta pots and copper tubing purchased at the local hardware store and voltage measurements collected with handle held multi-meters. D.C. resistivity data were collected in a dipole-dipole array using 20 nine volt batteries connected in series with a large enough variable resistor and amp meter to regulate steady current flow. A multi meter was used to collect voltage readings. Wenner array data were collected using a home-made multi-filament cable connected switch box to allow a central user to regulate current and take voltage reading. A map of conductivity produced from a 10 m of EM31 reading show that conductivity anomalies mirror topography. The SP profiles show high values in the playa lake that drop off as we move from the clay rich lake bed to normal grassland. Analysis of both the Dipole-Dipole and Wenner array data support a model with 3 flat layers increasing in resistivity with depth. It appears that these remain flat passing beneath the playa and the playa is eroded into these layers.

  16. Fibrinolytic and procoagulant activities of Yersinia pestis and Salmonella enterica.

    PubMed

    Korhonen, T K

    2015-06-01

    Pla of the plague bacterium Yersinia pestis and PgtE of the enteropathogen Salmonella enterica are surface-exposed, transmembrane β-barrel proteases of the omptin family that exhibit a complex array of interactions with the hemostatic systems in vitro, and both proteases are established virulence factors. Pla favors fibrinolysis by direct activation of plasminogen, inactivation of the serpins plasminogen activator inhibitor-1 and α2-antiplasmin, inactivation of the thrombin-activable fibrinolysis inhibitor, and activation of single-chain urokinase. PgtE is structurally very similar but exhibits partially different functions and differ in expression control. PgtE proteolysis targets control aspects of fibrinolysis, and mimicry of matrix metalloproteinases enhances cell migration that should favor the intracellular spread of the bacterium. Enzymatic activity of both proteases is strongly influenced by the environment-induced variations in lipopolysaccharide that binds to the β-barrel. Both proteases cleave the tissue factor pathway inhibitor and thus also express procoagulant activity. © 2015 International Society on Thrombosis and Haemostasis.

  17. EMIC Waves Observed in Conjunction with BARREL Electron Precipitation

    NASA Astrophysics Data System (ADS)

    Weaver, C.; Engebretson, M. J.; Lessard, M.; Halford, A. J.; Millan, R. M.; Horne, R. B.; Singer, H. J.

    2013-05-01

    Electromagnetic ion-cyclotron (EMIC) waves have been detected at Halley, Antarctica coinciding with observations of electron precipitation on high altitude balloons from the Balloon Array for RBSP Relativistic Electron Losses (BARREL) campaign launched in early 2013 from SANAE IV and Halley Station. The balloons were launched such that both spatial and temporal properties of electron precipitation might be examined. With a magnetic foot point mapped to the radiation belts, Halley is an ideal location to capture ground based signatures that coincide with electron precipitation. EMIC waves have been shown, both theoretically and through statistical surveys, to pitch angle scatter energetic protons and relativistic electrons via cyclotron resonance and contribute to radiation belt dynamics. EMIC waves were detected at Halley Station 23 times from 12 Jan - 4 Feb with 17 of those waves occurring during times when at least one BARREL balloon observed precipitation in one or more energy channels. High resolution magnetometer data from GOES 13 (which has a magnetic foot point near WAIS Divide, Antarctica-located about 2.5 hours, in MLT, west of Halley) show similar EMIC wave structure and frequency to 9 waves observed at Halley, suggesting the source region extended to at least the longitude and L value of GOES 13 during some events. The ground observed waves appeared in all local times and during both quiet and disturbed intervals.

  18. Post Oil America and a Renewable Energy Policy Leads to the Abrogation of the Middle East to China

    DTIC Science & Technology

    2009-04-01

    three issues. First is the fear that a terrorist incident on an oil rig or large refinery could disrupt the oil supply. The second is the concern...nuclear plants , wind farms, hydroelectric dams, and large solar arrays. Second, the economic vitality of the global community depends on the major...condensate, but excluding natural gas plant liquids).18 Multiply that amount by the average price of crude in 2006 of $66.4319 per barrel and the oil

  19. Corporatization and What We Can Do about It

    ERIC Educational Resources Information Center

    Fink, Leon

    2008-01-01

    "Corporatization," etymologically, likens developments in higher education to those of the business world. Like shooting fish in a barrel, however, merely identifying the multiplying examples of for-profit extrusions, managerial models, let alone ideological legitimations of capitalist logic on university campuses hardly constitutes an honest…

  20. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    Pumping helium into the first BARREL balloon to launch from Halley Research Satation. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  1. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    A crane lowers two BARREL balloon payloads onto the platform at Halley Research Station in Antarctica. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  2. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    The BARREL cargo on its four-hour journey from the supply ship to the research station. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  3. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    The BARREL team at the SANAE IV research station celebrates their final launch in the Antarctica sun. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  4. Plasticity-Related Gene 1 Affects Mouse Barrel Cortex Function via Strengthening of Glutamatergic Thalamocortical Transmission.

    PubMed

    Unichenko, Petr; Kirischuk, Sergei; Yang, Jenq-Wei; Baumgart, Jan; Roskoden, Thomas; Schneider, Patrick; Sommer, Angela; Horta, Guilherme; Radyushkin, Konstantin; Nitsch, Robert; Vogt, Johannes; Luhmann, Heiko J

    2016-07-01

    Plasticity-related gene-1 (PRG-1) is a brain-specific protein that modulates glutamatergic synaptic transmission. Here we investigated the functional role of PRG-1 in adolescent and adult mouse barrel cortex both in vitro and in vivo. Compared with wild-type (WT) animals, PRG-1-deficient (KO) mice showed specific behavioral deficits in tests assessing sensorimotor integration and whisker-based sensory discrimination as shown in the beam balance/walking test and sandpaper tactile discrimination test, respectively. At P25-31, spontaneous network activity in the barrel cortex in vivo was higher in KO mice compared with WT littermates, but not at P16-19. At P16-19, sensory evoked cortical responses in vivo elicited by single whisker stimulation were comparable in KO and WT mice. In contrast, at P25-31 evoked responses were smaller in amplitude and longer in duration in WT animals, whereas KO mice revealed no such developmental changes. In thalamocortical slices from KO mice, spontaneous activity was increased already at P16-19, and glutamatergic thalamocortical inputs to Layer 4 spiny stellate neurons were potentiated. We conclude that genetic ablation of PRG-1 modulates already at P16-19 spontaneous and evoked excitability of the barrel cortex, including enhancement of thalamocortical glutamatergic inputs to Layer 4, which distorts sensory processing in adulthood. © The Author 2016. Published by Oxford University Press.

  5. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel..., other than cranberries, in section 1 of the standard-barrel law, or any barrel or a subdivision thereof... than cranberries, or a legal subdivision thereof. No other barrel or subdivision in barrel form is a...

  6. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel..., other than cranberries, in section 1 of the standard-barrel law, or any barrel or a subdivision thereof... than cranberries, or a legal subdivision thereof. No other barrel or subdivision in barrel form is a...

  7. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel..., other than cranberries, in section 1 of the standard-barrel law, or any barrel or a subdivision thereof... than cranberries, or a legal subdivision thereof. No other barrel or subdivision in barrel form is a...

  8. Fabrication of long-focal-length plano-convex microlens array by combining the micro-milling and injection molding processes.

    PubMed

    Chen, Lei; Kirchberg, Stefan; Jiang, Bing-Yan; Xie, Lei; Jia, Yun-Long; Sun, Lei-Lei

    2014-11-01

    A uniform plano-convex spherical microlens array with a long focal length was fabricated by combining the micromilling and injection molding processes in this work. This paper presents a quantitative study of the injection molding process parameters on the uniformity of the height of the microlenses. The variation of the injection process parameters, i.e., barrel temperature, mold temperature, injection speed, and packing pressure, was found to have a significant effect on the uniformity of the height of the microlenses, especially the barrel temperature. The filling-to-packing switchover point is also critical to the uniformity of the height of the microlenses. The optimal uniformity was achieved when the polymer melts completely filled the mold cavity, or even a little excessively filled the cavity, during the filling stage. In addition, due to the filling resistance, the practical filling-to-packing switchover point can vary with the change of the filling processing conditions and lead to a non-negligible effect on the uniformity of the height of the microlenses. Furthermore, the effect of injection speed on the uniformity of the height of the microlenses was analyzed in detail. The results indicated that the effect of injection speed on the uniformity of the height of the microlenses is mainly attributed to the two functions of injection speed: transferring the filling-to-packing switchover point and affecting the distribution of residual flow stress in the polymer melt.

  9. Subcortical barrelette-like and barreloid-like structures in the prosimian galago (Otolemur garnetti)

    PubMed Central

    Sawyer, Eva Kille; Liao, Chia-Chi; Qi, Hui-Xin; Balaram, Pooja; Matrov, Denis; Kaas, Jon H.

    2015-01-01

    Galagos are prosimian primates that resemble ancestral primates more than most other extant primates. As in many other mammals, the facial vibrissae of galagos are distributed across the upper and lower jaws and above the eye. In rats and mice, the mystacial macrovibrissae are represented throughout the ascending trigeminal pathways as arrays of cytoarchitecturally distinct modules, with each module having a nearly one-to-one relationship with a specific facial whisker. The macrovibrissal representations are termed barrelettes in the trigeminal somatosensory brainstem, barreloids in the ventroposterior medial subnucleus of the thalamus, and barrels in primary somatosensory cortex. Despite the presence of facial whiskers in all nonhuman primates, barrel-like structures have not been reported in primates. By staining for cytochrome oxidase, Nissl, and vesicular glutamate transporter proteins, we show a distinct array of barrelette-like and barreloid-like modules in the principal sensory nucleus, the spinal trigeminal nucleus, and the ventroposterior medial subnucleus of the galago, Otolemur garnetti. Labeled terminals of primary sensory neurons in the brainstem and cell bodies of thalamocortically projecting neurons demonstrate that barrelette-like and barreloid-like modules are located in areas of these somatosensory nuclei that are topographically consistent with their role in facial touch. Serendipitously, the plane of section that best displays the barreloid-like modules reveals a remarkably distinct homunculus-like patterning which, we believe, is one of the clearest somatotopic maps of an entire body surface yet found. PMID:26038561

  10. Colleges' Earmarks Grow, Amid Criticism

    ERIC Educational Resources Information Center

    Brainard, Jeffrey; Hermes, J. J.

    2008-01-01

    A record-breaking number of Congressional pork-barrel projects this year has loaded college and university plates with more earmarks than ever before, despite growing worries that the noncompetitive grants undermine the American scientific enterprise, and in spite of promises by some lawmakers to cut back. An analysis by "The Chronicle" shows that…

  11. 15 CFR 240.6 - Tolerances.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE STANDARDS FOR BARRELS BARRELS AND OTHER CONTAINERS FOR LIME § 240.6 Tolerances. (a) When lime is packed in barrels the tolerance to be allowed on the large barrel or the small barrel of lime shall be 5 pounds in excess or in deficiency on any individual barrel...

  12. Optimization of performance parameters for large area silicon photomultipliers for use in the GlueX experiment

    NASA Astrophysics Data System (ADS)

    Janzen, Kathryn Louise

    Largely because of their resistance to magnetic fields, silicon photomultipliers (SiPMs) are being considered as the readout for the GlueX Barrel Calorimeter, a key component of the GlueX detector located immediately inside a 2.2 T superconducting solenoid. SiPMs with active area 1 x 1 mm2 have been investigated for use in other experiments, but detectors with larger active areas are required for the GlueX BCAL. This puts the GlueX collaboration in the unique position of being pioneers in the use of this frontend detection revolution by driving the technology for larger area sensors. SensL, a photonics research and development company in Ireland, has been collaborating with the University of Regina GlueX group to develop prototype large area SiPMs comprising 16 - 3x3 mm2 cells assembled in a close-packed matrix. Performance parameters of individual SensL 1x1 mm2 and 3x3 mm2 SiPMs along with prototype SensL SiPM arrays are tested, including current versus voltage characteristics, photon detection efficiency, and gain uniformity, in an effort to determine the suitability of these detectors to the GlueX BCAL readout.

  13. Investigation of EMIC wave scattering as the cause for the BARREL 17 January 2013 relativistic electron precipitation event: A quantitative comparison of simulation with observations

    DOE PAGES

    Li, Zan; Millan, Robyn M.; Hudson, Mary K.; ...

    2014-12-23

    Electromagnetic ion cyclotron (EMIC) waves were observed at multiple observatory locations for several hours on 17 January 2013. During the wave activity period, a duskside relativistic electron precipitation (REP) event was observed by one of the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL) balloons and was magnetically mapped close to Geostationary Operational Environmental Satellite (GOES) 13. We simulate the relativistic electron pitch angle diffusion caused by gyroresonant interactions with EMIC waves using wave and particle data measured by multiple instruments on board GOES 13 and the Van Allen Probes. We show that the count rate, the energy distribution,more » and the time variation of the simulated precipitation all agree very well with the balloon observations, suggesting that EMIC wave scattering was likely the cause for the precipitation event. The event reported here is the first balloon REP event with closely conjugate EMIC wave observations, and our study employs the most detailed quantitative analysis on the link of EMIC waves with observed REP to date.« less

  14. Investigation of EMIC wave scattering as the cause for the BARREL 17 January 2013 relativistic electron precipitation event: A quantitative comparison of simulation with observations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Zan; Millan, Robyn M.; Hudson, Mary K.

    Electromagnetic ion cyclotron (EMIC) waves were observed at multiple observatory locations for several hours on 17 January 2013. During the wave activity period, a duskside relativistic electron precipitation (REP) event was observed by one of the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL) balloons and was magnetically mapped close to Geostationary Operational Environmental Satellite (GOES) 13. We simulate the relativistic electron pitch angle diffusion caused by gyroresonant interactions with EMIC waves using wave and particle data measured by multiple instruments on board GOES 13 and the Van Allen Probes. We show that the count rate, the energy distribution,more » and the time variation of the simulated precipitation all agree very well with the balloon observations, suggesting that EMIC wave scattering was likely the cause for the precipitation event. The event reported here is the first balloon REP event with closely conjugate EMIC wave observations, and our study employs the most detailed quantitative analysis on the link of EMIC waves with observed REP to date.« less

  15. Small arms mini-fire control system: fiber-optic barrel deflection sensor

    NASA Astrophysics Data System (ADS)

    Rajic, S.; Datskos, P.; Lawrence, W.; Marlar, T.; Quinton, B.

    2012-06-01

    Traditionally the methods to increase firearms accuracy, particularly at distance, have concentrated on barrel isolation (free floating) and substantial barrel wall thickening to gain rigidity. This barrel stiffening technique did not completely eliminate barrel movement but the problem was significantly reduced to allow a noticeable accuracy enhancement. This process, although highly successful, came at a very high weight penalty. Obviously the goal would be to lighten the barrel (firearm), yet achieve even greater accuracy. Thus, if lightweight barrels could ultimately be compensated for both their static and dynamic mechanical perturbations, the result would be very accurate, yet significantly lighter weight, weapons. We discuss our development of a barrel reference sensor system that is designed to accomplish this ambitious goal. Our optical fiber-based sensor monitors the barrel muzzle position and autonomously compensates for any induced perturbations. The reticle is electronically adjusted in position to compensate for the induced barrel deviation in real time.

  16. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    BARREL team members run under the payload as the balloon first takes flight at the SANAE IV research station in Antarctica. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  17. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    An iceberg as viewed from the bow of the RRS Ernest Shackleton a few days before the BARREL team reached Halley Research Station in Antarctica. This research vessel regularly carries scientists and supplies to Halley. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  18. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    An emperor penguin waddles away on Christmas morning in Antarctica. On Christmas day, the BARREL team visited a penguin colony. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  19. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    Arrival of the RRS Ernest Shackleton near Halley Research Station in Antarctica. The Shackleton is the regular resupply ship for the station and it also brought in some of the BARREL team scientists. The long tether is for the ship’s mooring. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  20. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    Watching a BARREL balloon – and the instruments dangling below – float up over the SANAE IV research base in Antarctica. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  1. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    Some of the BARREL balloon launches took place at the South African National Antarctic Expedition Research base, called SANAE IV, the others at Halley Research Station. This balloon is taking flight at SANAE IV. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  2. Small arms mini-fire control system: fiber-optic barrel deflection sensor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rajic, Slobodan; Datskos, Panos G

    Traditionally the methods to increase firearms accuracy, particularly at distance, have concentrated on barrel isolation (free floating) and substantial barrel wall thickening to gain rigidity. This barrel stiffening technique did not completely eliminate barrel movement but the problem was significantly reduced to allow a noticeable accuracy enhancement. This process, although highly successful, came at a very high weight penalty. Obviously the goal would be to lighten the barrel (firearm), yet achieve even greater accuracy. Thus, if lightweight barrels could ultimately be compensated for both their static and dynamic mechanical perturbations, the result would be very accurate, yet significantly lighter weight,more » weapons. We discuss our development of a barrel reference sensor system that is designed to accomplish this ambitious goal. Our optical fiber-based sensor monitors the barrel muzzle position and autonomously compensates for any induced perturbations. The reticle is electronically adjusted in position to compensate for the induced barrel deviation in real time.« less

  3. Hired Guns Help Colleges Feed at the Pork Barrel.

    ERIC Educational Resources Information Center

    Brainard, Jeffrey

    2000-01-01

    Reports on the trend for increased earmarking of federal funds for specific colleges and universities and the accompanying rise in Congressional lobbying by these institutions. Identifies the 10 institutions that spent the most on independent lobbyists in 1999 as well as the 10 lobbying firms that billed academe the most. Notes the high costs and…

  4. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Legal standard barrels. 241.2 Section..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel... form or dimensions, is a legal standard barrel for fruits, vegetables, or other dry commodities other...

  5. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Legal standard barrels. 241.2 Section..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel... form or dimensions, is a legal standard barrel for fruits, vegetables, or other dry commodities other...

  6. Status and performance of the ALICE MRPC-based Time-Of-Flight detector

    NASA Astrophysics Data System (ADS)

    Alici, A.

    2012-10-01

    ALICE is the dedicated heavy-ion experiment at the CERN LHC. One of the main detectors devoted to charged hadron identification in the ALICE central barrel is a large Time-Of-Flight (TOF) array; it allows separation among pions, kaons and protons up to a few GeV/c, covering the full azimuthal angle and -0.9 < η < 0.9. The very good performance required for such a system has been achieved by means of the Multigap Resistive Plate Chamber (MRPC) whose intrinsic time resolution is better than 50 ps with an overall efficiency close to 100% and a large operational plateau; the full array consists of 1593 MRPCs covering a cylindrical surface of 141 m2. In this report, the status of the TOF detector and the performance achieved during the 2010 and 2011 data taking periods are reported together with selected physics results obtained with pp and Pb-Pb collisions.

  7. Active C4 Electrodes for Local Field Potential Recording Applications

    PubMed Central

    Wang, Lu; Freedman, David; Sahin, Mesut; Ünlü, M. Selim; Knepper, Ronald

    2016-01-01

    Extracellular neural recording, with multi-electrode arrays (MEAs), is a powerful method used to study neural function at the network level. However, in a high density array, it can be costly and time consuming to integrate the active circuit with the expensive electrodes. In this paper, we present a 4 mm × 4 mm neural recording integrated circuit (IC) chip, utilizing IBM C4 bumps as recording electrodes, which enable a seamless active chip and electrode integration. The IC chip was designed and fabricated in a 0.13 μm BiCMOS process for both in vitro and in vivo applications. It has an input-referred noise of 4.6 μVrms for the bandwidth of 10 Hz to 10 kHz and a power dissipation of 11.25 mW at 2.5 V, or 43.9 μW per input channel. This prototype is scalable for implementing larger number and higher density electrode arrays. To validate the functionality of the chip, electrical testing results and acute in vivo recordings from a rat barrel cortex are presented. PMID:26861324

  8. Development of a novel scintillation-trigger detector for the MTV experiment using aluminum-metallized film tapes

    NASA Astrophysics Data System (ADS)

    Tanaka, S.; Ozaki, S.; Sakamoto, Y.; Tanuma, R.; Yoshida, T.; Murata, J.

    2014-07-01

    A new type of a trigger-scintillation counter array designed for the MTV experiment at TRIUMF-ISAC has been developed, which uses aluminum-metallized film tape for wrapping to achieve the required assembling precision of ±0.5 mm. The MTV experiment uses a cylindrical drift chamber (CDC) as the main electron-tracking detector. The barrel-type trigger counter is placed inside the CDC to generate a trigger signal using 1 mm thick, 300 mm long thin plastic scintillation counters. Detection efficiency and light attenuation compared with conventional wrapping materials are studied.

  9. Assessment of undiscovered oil and gas resources of the Assam, Bombay, Cauvery, and Krishna-Godavari Provinces, South Asia, 2011

    USGS Publications Warehouse

    Klett, T.R.; Schenk, Christopher J.; Wandrey, Craig J.; Charpentier, Ronald R.; Cook, Troy A.; Brownfield, Michael E.; Pitman, Janet K.; Pollastro, Richard M.

    2012-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated volumes of undiscovered, technically recoverable, conventional petroleum resources for the Assam, Bombay, Cauvery, and Krishna–Godavari Provinces, South Asia. The estimated mean volumes are as follows: (1) Assam Province, 273 million barrels of crude oil, 1,559 billion cubic feet of natural gas, and 43 million barrels of natural gas liquids; (2) Bombay Province, 1,854 million barrels of crude oil, 15,417 billion cubic feet of natural gas, and 498 million barrels of natural gas liquids; (3) Cauvery Province, 941 million barrels of crude oil, 25,208 billion cubic feet of natural gas, and 654 million barrels of natural gas liquids; and (4) Krishna–Godavari Province, 466 million barrels of crude oil, 37,168 billion cubic feet of natural gas, and 484 million barrels of natural gas liquids. The totals for the four provinces are 3,534 million barrels of crude oil, 79,352 billion cubic feet of natural gas, and 1,679 million barrels of natural gas liquids.

  10. 15 CFR 240.3 - Permissible sizes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE STANDARDS FOR BARRELS BARRELS AND OTHER CONTAINERS FOR LIME § 240.3 Permissible sizes. Lime in barrels shall be packed only in barrels containing 280 pounds or 180...

  11. 3D Finite Element Modeling of Sliding Wear

    DTIC Science & Technology

    2013-12-01

    the high strain rate compression of three armor materials: Maraging steel 300, high hardness armor (HHA), and aluminum alloy 5083. The University of...bearings, gears, brakes, gun barrels , slippers, locomotive wheels, or even rocket test tracks. The 3D wear model presented in this dissertation allows...43 Figure III-18 AISI-1080 Steel Distribution of Asperities..................................... 45 Figure III-19 Micrograph of Worn

  12. Self-Assembling Protein Nanostructures - Towards Active Functionality

    DTIC Science & Technology

    2011-04-22

    the (alpha-beta)8 barrel. A model thermophilic enzyme , natively a tetramer, was engineered as a monomer, a dimer (submitted to Biochimica et...problem. Objective one successfully built high surface area nanoscaffolds from amyloid fibrils, and demonstrated that enzyme activity could be attached...quaternary structure, amyloid fibril, organophosphorous hydrolase, enzyme Juliet Gerrard University of Canterbury 20 Kirkwood Ave Ilam 8041 - REPORT

  13. Oil burner nozzle

    DOEpatents

    Wright, Donald G.

    1982-01-01

    An oil burner nozzle for use with liquid fuels and solid-containing liquid fuels. The nozzle comprises a fuel-carrying pipe, a barrel concentrically disposed about the pipe, and an outer sleeve retaining member for the barrel. An atomizing vapor passes along an axial passageway in the barrel, through a bore in the barrel and then along the outer surface of the front portion of the barrel. The atomizing vapor is directed by the outer sleeve across the path of the fuel as it emerges from the barrel. The fuel is atomized and may then be ignited.

  14. De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy

    PubMed Central

    Parmeggiani, Fabio; Velasco, D. Alejandro Fernandez; Höcker, Birte; Baker, David

    2015-01-01

    Despite efforts for over 25 years, de novo protein design has not succeeded in achieving the TIM-barrel fold. Here we describe the computational design of 4-fold symmetrical (β/α)8-barrels guided by geometrical and chemical principles. Experimental characterization of 33 designs revealed the importance of sidechain-backbone hydrogen bonding for defining the strand register between repeat units. The X-ray crystal structure of a designed thermostable 184-residue protein is nearly identical with the designed TIM-barrel model. PSI-BLAST searches do not identify sequence similarities to known TIM-barrel proteins, and sensitive profile-profile searches indicate that the design sequence is distant from other naturally occurring TIM-barrel superfamilies, suggesting that Nature has only sampled a subset of the sequence space available to the TIM-barrel fold. The ability to de novo design TIM-barrels opens new possibilities for custom-made enzymes. PMID:26595462

  15. Optimization of Injection Molding Parameters for HDPE/TiO₂ Nanocomposites Fabrication with Multiple Performance Characteristics Using the Taguchi Method and Grey Relational Analysis.

    PubMed

    Pervez, Hifsa; Mozumder, Mohammad S; Mourad, Abdel-Hamid I

    2016-08-22

    The current study presents an investigation on the optimization of injection molding parameters of HDPE/TiO₂ nanocomposites using grey relational analysis with the Taguchi method. Four control factors, including filler concentration (i.e., TiO₂), barrel temperature, residence time and holding time, were chosen at three different levels of each. Mechanical properties, such as yield strength, Young's modulus and elongation, were selected as the performance targets. Nine experimental runs were carried out based on the Taguchi L₉ orthogonal array, and the data were processed according to the grey relational steps. The optimal process parameters were found based on the average responses of the grey relational grades, and the ideal operating conditions were found to be a filler concentration of 5 wt % TiO₂, a barrel temperature of 225 °C, a residence time of 30 min and a holding time of 20 s. Moreover, analysis of variance (ANOVA) has also been applied to identify the most significant factor, and the percentage of TiO₂ nanoparticles was found to have the most significant effect on the properties of the HDPE/TiO₂ nanocomposites fabricated through the injection molding process.

  16. Construction and performance of the barrel electromagnetic calorimeter for the GlueX experiment

    NASA Astrophysics Data System (ADS)

    Beattie, T. D.; Foda, A. M.; Henschel, C. L.; Katsaganis, S.; Krueger, S. T.; Lolos, G. J.; Papandreou, Z.; Plummer, E. L.; Semenova, I. A.; Semenov, A. Yu.; Barbosa, F.; Chudakov, E.; Dalton, M. M.; Lawrence, D.; Qiang, Y.; Sandoval, N.; Smith, E. S.; Stanislav, C.; Stevens, J. R.; Taylor, S.; Whitlatch, T.; Zihlmann, B.; Levine, W.; McGinley, W.; Meyer, C. A.; Staib, M. J.; Anassontzis, E.; Kourkoumelis, C.; Vasileiadis, G.; Voulgaris, G.; Brooks, W. K.; Hakobyan, H.; Kuleshov, S.; Rojas, R.; Romero, C.; Soto, O.; Toro, A.; Vega, I.; Shepherd, M. R.

    2018-07-01

    The barrel calorimeter is part of the new spectrometer installed in Hall D at Jefferson Lab for the GlueX experiment. The calorimeter was installed in 2013, commissioned in 2014 and has been operating routinely since early 2015. The detector configuration, associated Monte Carlo simulations, calibration and operational performance are described herein. The calorimeter records the time and energy deposited by charged and neutral particles created by a multi-GeV photon beam. It is constructed as a lead and scintillating-fiber calorimeter and read out with 3840 large-area silicon photomultiplier arrays. Particles impinge on the detector over a wide range of angles, from normal incidence at 90 degrees down to 11.5 degrees, which defines a geometry that is fairly unique among calorimeters. The response of the calorimeter has been measured during a running experiment and performs as expected for electromagnetic showers below 2.5 GeV. We characterize the performance of the BCAL using the energy resolution integrated over typical angular distributions for π0 and η production of σE / E = 5 . 2% /√{ E(GeV) } ⊕ 3 . 6% and a timing resolution of σ = 150 ps at 1 GeV.

  17. Visualization of newt aragonitic otoconial matrices using transmission electron microscopy

    NASA Technical Reports Server (NTRS)

    Steyger, P. S.; Wiederhold, M. L.

    1995-01-01

    Otoconia are calcified protein matrices within the gravity-sensing organs of the vertebrate vestibular system. These protein matrices are thought to originate from the supporting or hair cells in the macula during development. Previous studies of mammalian calcitic, barrel-shaped otoconia revealed an organized protein matrix consisting of a thin peripheral layer, a well-defined organic core and a flocculent matrix inbetween. No studies have reported the microscopic organization of the aragonitic otoconial matrix, despite its protein characterization. Pote et al. (1993b) used densitometric methods and inferred that prismatic (aragonitic) otoconia have a peripheral protein distribution, compared to that described for the barrel-shaped, calcitic otoconia of birds, mammals, and the amphibian utricle. By using tannic acid as a negative stain, we observed three kinds of organic matrices in preparations of fixed, decalcified saccular otoconia from the adult newt: (1) fusiform shapes with a homogenous electron-dense matrix; (2) singular and multiple strands of matrix; and (3) more significantly, prismatic shapes outlined by a peripheral organic matrix. These prismatic shapes remain following removal of the gelatinous matrix, revealing an internal array of organic matter. We conclude that prismatic otoconia have a largely peripheral otoconial matrix, as inferred by densitometry.

  18. An improved method for constructing and selectively silanizing double-barreled, neutral liquid-carrier, ion-selective microelectrodes

    PubMed Central

    Deveau, Jason S.T.; Grodzinski, Bernard

    2005-01-01

    We describe an improved, efficient and reliable method for the vapour-phase silanization of multi-barreled, ion-selective microelectrodes of which the silanized barrel(s) are to be filled with neutral liquid ion-exchanger (LIX). The technique employs a metal manifold to exclusively and simultaneously deliver dimethyldichlorosilane to only the ion-selective barrels of several multi-barreled microelectrodes. Compared to previously published methods the technique requires fewer procedural steps, less handling of individual microelectrodes, improved reproducibility of silanization of the selected microelectrode barrels and employs standard borosilicate tubing rather than the less-conventional theta-type glass. The electrodes remain stable for up to 3 weeks after the silanization procedure. The efficacy of a double-barreled electrode containing a proton ionophore in the ion-selective barrel is demonstrated in situ in the leaf apoplasm of pea (Pisum) and sunflower (Helianthus). Individual leaves were penetrated to depth of ~150 μm through the abaxial surface. Microelectrode readings remained stable after multiple impalements without the need for a stabilizing PVC matrix. PMID:16136222

  19. Astringency, bitterness and color changes in dry red wines before and during oak barrel aging: An updated phenolic perspective review.

    PubMed

    Li, Si-Yu; Duan, Chang-Qing

    2018-01-30

    To understand effects of using oak barrels on the astringency, bitterness and color of dry red wines, phenolic reactions in wines before and after barrel aging are reviewed in this paper, which has been divided into three sections. The first section includes an introduction to chemical reactivities of grape-derived phenolic compounds, a summary of the phenolic reactions that occur in dry red wines before barrel aging, and a discussion of the effects of these reactions on wine astringency, bitterness and color. The second section introduces barrel types that determine the oak barrel constituents in wines (primarily oak aldehydes and ellagitannins) and presents reactions between the oak constituents and grape-derived phenolic compounds that may modulate wine astringency, bitterness and color. The final section illustrates the chemical differences between basic oxidation and over-oxidation in wines, discusses oxygen consumption kinetics in wines during barrel aging by comparing different oxygen consumption kinetics observed previously by others, and speculates on the possible preliminary phenolic reactions that occur in dry red wines during oak barrel aging that soften tannins and stabilize pigments via basic oxidation. Additionally, sulfur dioxide (SO 2 ) addition during barrel aging and suitability of adopting oak barrels for aging wines are briefly discussed.

  20. 15 CFR 240.1 - Title of act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE STANDARDS FOR BARRELS BARRELS AND OTHER CONTAINERS FOR LIME... U.S.C. 237-242), entitled “An Act to standardize lime barrels,” shall be known and referred to as the “Standard Lime-Barrel Act.” ...

  1. Reduction of Gun Erosion and Correlation of Gun Erosion Measurements

    NASA Technical Reports Server (NTRS)

    Bogdanoff, Dave; Wercinski, Paul (Technical Monitor)

    1997-01-01

    Gun barrel erosion is serious problem with two-stage light gas guns. Excessive barrel erosion can lead to poor or failed launches and frequent barrel changes, with the corresponding down time. Also, excessive barrel erosion can limit the maximum velocity obtainable by loading down the hydrogen working gas with eroded barrel material. Guided by a CFD code, the operating conditions of the Ames 0.5-inch gun were modified to reduce barrel erosion. The changes implemented included: (1) reduction in the piston mass, powder mass and hydrogen fill pressure; and (2) reduction in pump tube volume, while maintaining hydrogen mass. The latter change was found, in particular, to greatly reduce barrel erosion. For muzzle velocity ranges of 6.1 - 6.9 km/sec, the barrel erosion was reduced by a factor of 10. Even for the higher muzzle velocity range of 7.0 - 8.2 km/sec, the barrel erosion was reduced by a factor of 4. Gun erosion data from the Ames 0.5-inch, 1.0-inch, and 1.5-inch guns operated over a wide variety of launch conditions was examined and it was found that this data could be correlated using four different parameters: normalized powder charge energy, normalized hydrogen energy density, normalized pump tube volume and barrel diameter. The development of the correlation and the steps used to collapse the experimental data are presented. Over a certain parameter range in the correlation developed, the barrel erosion per shot is found to increase very rapidly. The correlation should prove useful in the selection of gun operating conditions and the design of new guns. Representative shapes of eroded gun barrels are also presented.

  2. EMIC waves and associated relativistic electron precipitation on 25-26 January 2013

    DOE PAGES

    Zhang, Jichun; Halford, Alexa J.; Saikin, Anthony A.; ...

    2016-10-28

    Using measurements from the Van Allen Probes and the Balloon Array for RBSP Relativistic Electron Losses (BARREL), we perform a case study of electromagnetic ion cyclotron (EMIC) waves and associated relativistic electron precipitation (REP) observed on 25–26 January 2013. Among all the EMIC wave and REP events from the two missions, the pair of the events is the closest both in space and time. The Van Allen Probe-B detected significant EMIC waves at L = 2.1–3.9 and magnetic local time (MLT) = 21.0–23.4 for 53.5 min from 2353:00 UT, 25 January 2013. Meanwhile, BARREL-1T observed clear precipitation of relativistic electronsmore » at L = 4.2–4.3 and MLT = 20.7–20.8 for 10.0 min from 2358 UT, 25 January 2013. Local plasma and field conditions for the excitation of the EMIC waves, wave properties, electron minimum resonant energy E min, and electron pitch angle diffusion coefficient D αα of a sample EMIC wave packet are examined along with solar wind plasma and interplanetary magnetic field parameters, geomagnetic activity, and results from the spectral analysis of the BARREL balloon observations to investigate the two types of events. The events occurred in the early main phase of a moderate storm (min. Dst* = -51.0 nT). The EMIC wave event consists of two parts. Finally, unlike the first part, the second part of the EMIC wave event was locally generated and still in its source region. It is found that the REP event is likely associated with the EMIC wave event.« less

  3. EMIC waves and associated relativistic electron precipitation on 25-26 January 2013

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Jichun; Halford, Alexa J.; Saikin, Anthony A.

    Using measurements from the Van Allen Probes and the Balloon Array for RBSP Relativistic Electron Losses (BARREL), we perform a case study of electromagnetic ion cyclotron (EMIC) waves and associated relativistic electron precipitation (REP) observed on 25–26 January 2013. Among all the EMIC wave and REP events from the two missions, the pair of the events is the closest both in space and time. The Van Allen Probe-B detected significant EMIC waves at L = 2.1–3.9 and magnetic local time (MLT) = 21.0–23.4 for 53.5 min from 2353:00 UT, 25 January 2013. Meanwhile, BARREL-1T observed clear precipitation of relativistic electronsmore » at L = 4.2–4.3 and MLT = 20.7–20.8 for 10.0 min from 2358 UT, 25 January 2013. Local plasma and field conditions for the excitation of the EMIC waves, wave properties, electron minimum resonant energy E min, and electron pitch angle diffusion coefficient D αα of a sample EMIC wave packet are examined along with solar wind plasma and interplanetary magnetic field parameters, geomagnetic activity, and results from the spectral analysis of the BARREL balloon observations to investigate the two types of events. The events occurred in the early main phase of a moderate storm (min. Dst* = -51.0 nT). The EMIC wave event consists of two parts. Finally, unlike the first part, the second part of the EMIC wave event was locally generated and still in its source region. It is found that the REP event is likely associated with the EMIC wave event.« less

  4. Coring device with a improved core sleeve and anti-gripping collar with a collective core catcher

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Story, A.L.; Filshtinsky, M.

    1986-01-28

    This patent describes an improved coring apparatus used in combination with a coring bit and drill string. This device consists of: an outer driving structure adapted to be connected at one end to the coring bit for cutting a core in a borehole, and at the other end to the lower end of the drill string in telescoping and co-rotatable manner therewith; an inner barrel disposed within the outer driving structure and including a lower end portion adjacent to the bit; first means supporting the inner barrel in spaced relationship to the outer driving structure while permitting rotation of themore » driving structure with respect to the inner barrel; a woven metal mesh sleeve mounted in surrounding relation on at least a portion of the exterior surface of the inner barrel; second means, connected to a free end of the sleeve opposite the leading portion of the sleeve, for maintaining the portion of the sleeve which surrounds the inner barrel in compression and to maintain an inside diameter greater than the outside diameter of the inner barrel of the portion of the sleeve surrounding the inner barrel while the portion of the sleeve positioned inside the inner barrel being in tension to grip and compress a core received within the sleeve and having an outside diameter less than the inside diameter of the inner barrel when in tension, wherein the second means is also for engaging the core when the means is drawn into the inner barrel, and third means positioned within the inner barrel and connected to the leading portion of the sleeve to draw the sleeve within the inner barrel and to apply tension to the portion of the sleeve within the barrel to encase and grip the core as it is cut.« less

  5. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    A BARREL balloon floats into the sky as it is partially filled. When fully inflated, each balloon is 90 feet in diameter and carries an instrument suite that weighs 50 pounds. This is small for an Antarctica balloon launch, which can have balloons Typical balloons l the size of a football field with payloads of some 3,000 pounds. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  6. Vesicular glutamate transporters VGLUT1 and VGLUT2 in the developing mouse barrel cortex.

    PubMed

    Liguz-Lecznar, M; Skangiel-Kramska, J

    2007-04-01

    Three vesicular glutamate transporters have been identified in mammals. Two of them, VGLUT1 and VGLUT2, define the glutamatergic phenotype and their distribution in the brain is almost complementary. In the present study we examined the distribution and expression levels of these two VGLUTs during postnatal development of the mouse barrel cortex. We also investigated changes in the localization of VGLUT1 and VGLUT2 within particular compartments of the barrel field (barrels/septa) during its development. We found differences in the time course of developmental expression, with VGLUT1 peaking around P14, while VGLUT2 increased gradually until adulthood. Over the examined period (P3 - adult) both transporters had stronger expression in the barrel interiors, and in this compartment VGLUT2 dominated, whereas in the inter-barrel septa VGLUT1 dominated over VGLUT2. Furthermore, we found that some nerve terminals in the barrel cortex coexpressed both transporters until adulthood. Colocalization was observed within the barrels, but not within the septa.

  7. Nanotechnology: A Policy Primer

    DTIC Science & Technology

    2010-06-02

    States of 24 million barrels of oil.3 • Universal access to clean water. Nanotechnology water desalination and filtration systems may offer...CRS Report for Congress Prepared for Members and Committees of Congress Nanotechnology : A Policy Primer John F. Sargent Jr. Specialist...00-00-2010 to 00-00-2010 4. TITLE AND SUBTITLE Nanotechnology : A Policy Primer 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

  8. 15 CFR 240.2 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE STANDARDS FOR BARRELS BARRELS AND OTHER CONTAINERS FOR LIME... to lime in barrels, or other containers packed, sold, or offered for sale for shipment from any State...; and to lime in containers of less capacity than the standard small barrel sold in interstate or...

  9. Cultured embryonic non-innervated mouse muzzle is capable of generating a whisker pattern.

    PubMed

    Andrés, F L; Van Der Loos, H

    1983-01-01

    The whisker pattern on the muzzle of the mouse is mapped in the contralateral parietal neocortex, each whisker follicle projecting to its own multineuronal unit ('barrel'). To determine the role, if any, of the peripheral innervation in the establishment of the vibrissal array, we cultured non-innervated prospective whiskerpads from 9- and 10-day-old embryos, mostly on chorioallantoic membrane. The results show that skin, alone, is capable of generating the whisker pattern, thus adducing a strong argument for the hypothesis that the central brain maps have their origin in the periphery. Copyright © 1983. Published by Elsevier Ltd.

  10. Response sensitivity of barrel neuron subpopulations to simulated thalamic input.

    PubMed

    Pesavento, Michael J; Rittenhouse, Cynthia D; Pinto, David J

    2010-06-01

    Our goal is to examine the relationship between neuron- and network-level processing in the context of a well-studied cortical function, the processing of thalamic input by whisker-barrel circuits in rodent neocortex. Here we focus on neuron-level processing and investigate the responses of excitatory and inhibitory barrel neurons to simulated thalamic inputs applied using the dynamic clamp method in brain slices. Simulated inputs are modeled after real thalamic inputs recorded in vivo in response to brief whisker deflections. Our results suggest that inhibitory neurons require more input to reach firing threshold, but then fire earlier, with less variability, and respond to a broader range of inputs than do excitatory neurons. Differences in the responses of barrel neuron subtypes depend on their intrinsic membrane properties. Neurons with a low input resistance require more input to reach threshold but then fire earlier than neurons with a higher input resistance, regardless of the neuron's classification. Our results also suggest that the response properties of excitatory versus inhibitory barrel neurons are consistent with the response sensitivities of the ensemble barrel network. The short response latency of inhibitory neurons may serve to suppress ensemble barrel responses to asynchronous thalamic input. Correspondingly, whereas neurons acting as part of the barrel circuit in vivo are highly selective for temporally correlated thalamic input, excitatory barrel neurons acting alone in vitro are less so. These data suggest that network-level processing of thalamic input in barrel cortex depends on neuron-level processing of the same input by excitatory and inhibitory barrel neurons.

  11. A radial map of multi-whisker correlation selectivity in the rat barrel cortex.

    PubMed

    Estebanez, Luc; Bertherat, Julien; Shulz, Daniel E; Bourdieu, Laurent; Léger, Jean-François

    2016-11-21

    In the barrel cortex, several features of single-whisker stimuli are organized in functional maps. The barrel cortex also encodes spatio-temporal correlation patterns of multi-whisker inputs, but so far the cortical mapping of neurons tuned to such input statistics is unknown. Here we report that layer 2/3 of the rat barrel cortex contains an additional functional map based on neuronal tuning to correlated versus uncorrelated multi-whisker stimuli: neuron responses to uncorrelated multi-whisker stimulation are strongest above barrel centres, whereas neuron responses to correlated and anti-correlated multi-whisker stimulation peak above the barrel-septal borders, forming rings of multi-whisker synchrony-preferring cells.

  12. Explosively driven hypervelocity launcher: Second-stage augmentation techniques

    NASA Technical Reports Server (NTRS)

    Baum, D. W.

    1973-01-01

    The results are described of a continuing study aimed at developing a two-stage explosively driven hypervelocity launcher capable of achieving projectile velocities between 15 and 20 km/sec. The testing and evaluation of a new cylindrical impact technique for collapsing the barrel of two-stage launcher are reported. Previous two-stage launchers have been limited in ultimate performance by incomplete barrel collapse behind the projectile. The cylindrical impact technique explosively collapses a steel tube concentric with and surrounding the barrel of the launcher. The impact of the tube on the barrel produces extremely high stresses which cause the barrel to collapse. The collapse rate can be adjusted by appropriate variation of the explosive charge and tubing parameters. Launcher experiments demonstrated that the technique did achieve complete barrel collapse and form a second-stage piston. However, jetting occurred in the barrel collapse process and was responsible for severe projectile damage.

  13. Barrel maturation, oak alternatives and micro-oxygenation: influence on red wine aging and quality.

    PubMed

    Oberholster, A; Elmendorf, B L; Lerno, L A; King, E S; Heymann, H; Brenneman, C E; Boulton, R B

    2015-04-15

    The impact of micro-oxygenation (MOX) in conjunction with a variety of oak alternatives on phenolic composition and red wine aging was investigated and compared with traditional barrel aging. Although several studies concluded that MOX give similar results to barrel aging, few have compared them directly and none directly compared MOX with and without wood alternatives and barrel aging. Results confirmed that MOX had a positive effect on colour density, even after 5 months of bottle aging. This is supported by an increase in polymeric phenol and pigment content not only with aging but in the MOX compared to barrel matured wine treatments. Descriptive analysis showed that MOX in combination with wood alternatives such as oak chips and staves could mimic short term (six months) barrel aging in new American and French oak barrels in regards to sensory characteristics. Published by Elsevier Ltd.

  14. Development of explosively driven launcher for meteoroid studies

    NASA Technical Reports Server (NTRS)

    Baum, D. W.

    1973-01-01

    The results of a continuing program to develop an explosively driven 2-stage hypervelocity launcher capable of achieving velocities between 15 and 20 km/sec are described. Previous efforts had identified incomplete barrel collapse as a limiting factor in launcher performance. Correlation of experimental and computational results obtained in the present study indicate that boundary-layer gases within the barrel act to prevent complete closure. Simplified calculations suggest that in-contact explosives may have insufficient energy densities to collapse the barrel against a developed boundary layer. Higher energy densities, sufficient to produce complete closure, were obtained with the use of steel flyer plates accelerated by a phased explosive lens. However, when flat flyer plates were impacted on the barrel, the sides of the barrel were observed to rupture and leak gas prior to barrel closure. A promising solution to this problem (untested) is to produce a symmetrical collapse with a cylindrical tube around the barrel.

  15. 15 CFR 240.4 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE STANDARDS FOR BARRELS BARRELS AND OTHER CONTAINERS FOR LIME... container not in barrel form containing therein a net weight of lime of less than 180 pounds. (b) The term... matter upon the surface of a barrel or other container of lime subject to the provisions of this act, or...

  16. Barrels XXX meeting report: Barrels in Baltimore.

    PubMed

    Shin, Hyeyoung; Bitzidou, Malamati; Palaguachi, Fernando; Brumberg, Joshua C

    2018-03-01

    The Barrels meeting annually brings together researchers focused on the rodent whisker to cortical barrel system prior to the Society for Neuroscience meeting. The 2017 meeting focused on the classification of cortical interneurons, the role interneurons have in shaping brain dynamics, and finally on the circuitry underlying oral sensations. The meeting highlighted the latest advancements in this rapidly advancing field.

  17. 77 FR 32986 - Notice of Inventory Completion: The University of Alabama Museums, Tuscaloosa, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... than 2,032 glass beads, 1 lot of more than 17 shell beads, 1 unidentified bead, 1 gun lock, 1 gun butt plate, 1 gun stock, 2 gun barrels, 1 brass ramrod support, 8 musket balls, 2 iron buckles, 1 iron handle... fragments, 1 unidentified bead, 2 glass beads, 1 gun flint, 1 iron knife blade, 1 iron nail, 1 musket ball...

  18. Development of a continuous roll-to-roll processing system for mass production of plastic optical film

    NASA Astrophysics Data System (ADS)

    Chang, Chih-Yuan; Tsai, Meng-Hsun

    2015-12-01

    This paper reports a highly effective method for the mass production of large-area plastic optical films with a microlens array pattern based on a continuous roll-to-roll film extrusion and roller embossing process. In this study, a thin steel mold with a micro-circular hole array pattern is fabricated by photolithography and a wet chemical etching process. The thin steel mold was then wrapped onto a metal cylinder to form an embossing roller mold. During the roll-to-roll process operation, a thermoplastic raw material (polycarbonate grains) was put into the barrel of the plastic extruder with a flat T-die. Then, the molten polymer film was extruded and immediately pressed against the surface of the embossing roller mold. Under the proper processing conditions, the molten polymer will just partially fill the micro-circular holes of the mold and due to surface tension form a convex lens surface. A continuous plastic optical film with a microlens array pattern was obtained. Experiments are carried out to investigate the effect of plastic microlens formation on the roll-to-roll process. Finally, the geometrical and optical properties of the fabricated plastic optical film were measured and proved satisfactory. This technique shows great potential for the mass production of large-area plastic optical films with a microlens array pattern.

  19. High Stimulus-Related Information in Barrel Cortex Inhibitory Interneurons

    PubMed Central

    Reyes-Puerta, Vicente; Kim, Suam; Sun, Jyh-Jang; Imbrosci, Barbara; Kilb, Werner; Luhmann, Heiko J.

    2015-01-01

    The manner in which populations of inhibitory (INH) and excitatory (EXC) neocortical neurons collectively encode stimulus-related information is a fundamental, yet still unresolved question. Here we address this question by simultaneously recording with large-scale multi-electrode arrays (of up to 128 channels) the activity of cell ensembles (of up to 74 neurons) distributed along all layers of 3–4 neighboring cortical columns in the anesthetized adult rat somatosensory barrel cortex in vivo. Using two different whisker stimulus modalities (location and frequency) we show that individual INH neurons – classified as such according to their distinct extracellular spike waveforms – discriminate better between restricted sets of stimuli (≤6 stimulus classes) than EXC neurons in granular and infra-granular layers. We also demonstrate that ensembles of INH cells jointly provide as much information about such stimuli as comparable ensembles containing the ~20% most informative EXC neurons, however presenting less information redundancy – a result which was consistent when applying both theoretical information measurements and linear discriminant analysis classifiers. These results suggest that a consortium of INH neurons dominates the information conveyed to the neocortical network, thereby efficiently processing incoming sensory activity. This conclusion extends our view on the role of the inhibitory system to orchestrate cortical activity. PMID:26098109

  20. Optimization of Injection Molding Parameters for HDPE/TiO2 Nanocomposites Fabrication with Multiple Performance Characteristics Using the Taguchi Method and Grey Relational Analysis

    PubMed Central

    Pervez, Hifsa; Mozumder, Mohammad S.; Mourad, Abdel-Hamid I.

    2016-01-01

    The current study presents an investigation on the optimization of injection molding parameters of HDPE/TiO2 nanocomposites using grey relational analysis with the Taguchi method. Four control factors, including filler concentration (i.e., TiO2), barrel temperature, residence time and holding time, were chosen at three different levels of each. Mechanical properties, such as yield strength, Young’s modulus and elongation, were selected as the performance targets. Nine experimental runs were carried out based on the Taguchi L9 orthogonal array, and the data were processed according to the grey relational steps. The optimal process parameters were found based on the average responses of the grey relational grades, and the ideal operating conditions were found to be a filler concentration of 5 wt % TiO2, a barrel temperature of 225 °C, a residence time of 30 min and a holding time of 20 s. Moreover, analysis of variance (ANOVA) has also been applied to identify the most significant factor, and the percentage of TiO2 nanoparticles was found to have the most significant effect on the properties of the HDPE/TiO2 nanocomposites fabricated through the injection molding process. PMID:28773830

  1. Construction and performance of the barrel electromagnetic calorimeter for the Gluex experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beattie, T. D.; Foda, A. M.; Henschel, C. L.

    Tmore » he barrel calorimeter is part of the new spectrometer installed in Hall D at Jefferson Lab for the GlueX experiment. he calorimeter was installed in 2013, commissioned in 2014 and has been operating routinely since early 2015. he detector configuration, associated Monte Carlo simulations, calibration and operational performance are described in this paper. he calorimeter records the time and energy deposited by charged and neutral particles created by a multi-GeV photon beam. It is constructed as a lead and scintillating-fiber calorimeter and read out with 3840 large-area silicon photomultiplier arrays. Particles impinge on the detector over a wide range of angles, from normal incidence at 90 degrees down to 11.5 degrees, which defines a geometry that is fairly unique among calorimeters. he response of the calorimeter has been measured during a running experiment and performs as expected for electromagnetic showers below 2.5 GeV. Finally, we characterize the performance of the BCAL using the energy resolution integrated over typical angular distributions for π 0 and η production of σ E / E = 5 . 2 % / E ( GeV ) ⊕ 3 . 6 % and a timing resolution of σ = 150 ps at 1 GeV.« less

  2. Construction and performance of the barrel electromagnetic calorimeter for the Gluex experiment

    DOE PAGES

    Beattie, T. D.; Foda, A. M.; Henschel, C. L.; ...

    2018-04-11

    Tmore » he barrel calorimeter is part of the new spectrometer installed in Hall D at Jefferson Lab for the GlueX experiment. he calorimeter was installed in 2013, commissioned in 2014 and has been operating routinely since early 2015. he detector configuration, associated Monte Carlo simulations, calibration and operational performance are described in this paper. he calorimeter records the time and energy deposited by charged and neutral particles created by a multi-GeV photon beam. It is constructed as a lead and scintillating-fiber calorimeter and read out with 3840 large-area silicon photomultiplier arrays. Particles impinge on the detector over a wide range of angles, from normal incidence at 90 degrees down to 11.5 degrees, which defines a geometry that is fairly unique among calorimeters. he response of the calorimeter has been measured during a running experiment and performs as expected for electromagnetic showers below 2.5 GeV. Finally, we characterize the performance of the BCAL using the energy resolution integrated over typical angular distributions for π 0 and η production of σ E / E = 5 . 2 % / E ( GeV ) ⊕ 3 . 6 % and a timing resolution of σ = 150 ps at 1 GeV.« less

  3. 7. View north at back (canal side) of culvert inlet, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. View north at back (canal side) of culvert inlet, with canal bank completely removed. Background to foreground: back of inlet headwall with tops of high inlet barrels exposed; vertical transition wall between high inlet barrels and low, interior, inlet barrels; tops of low interior barrels; vertical heartening planks and low cutoff wall at site of former canal edge of canal bank; dewatered canal bed and plank sheathing on top of culvert barrels beneath canal bed. - Delaware & Raritan Canal, Ten Mile Run Culvert, 1.5 miles South of Blackwells Road, East Millstone, Somerset County, NJ

  4. Invariant glycines and prolines flanking in loops the strand beta 2 of various (alpha/beta)8-barrel enzymes: a hidden homology?

    PubMed Central

    Janecek, S.

    1996-01-01

    The question of parallel (alpha/beta)8-barrel fold evolution remains unclear, owing mainly to the lack of sequence homology throughout the amino acid sequences of (alpha/beta)8-barrel enzymes. The "classical" approaches used in the search for homologies among (alpha/beta)8-barrels (e.g., production of structurally based alignments) have yielded alignments perfect from the structural point of view, but the approaches have been unable to reveal the homologies. These are proposed to be "hidden" in (alpha/beta)8-barrel enzymes. The term "hidden homology" means that the alignment of sequence stretches proposed to be homologous need not be structurally fully satisfactory. This is due to the very long evolutionary history of all (alpha/beta)8-barrels. This work identifies so-called hidden homology around the strand beta 2 that is flanked by loops containing invariant glycines and prolines in 17 different (alpha/beta)8-barrel enzymes, i.e., roughly in half of all currently known (alpha/beta)8-barrel proteins. The search was based on the idea that a conserved sequence region of an (alpha/beta)8-barrel enzyme should be more or less conserved also in the equivalent part of the structure of the other enzymes with this folding motif, given their mutual evolutionary relatedness. For this purpose, the sequence region around the well-conserved second beta-strand of alpha-amylase flanked by the invariant glycine and proline (56_GFTAIWITP, Aspergillus oryzae alpha-amylase numbering), was used as the sequence-structural template. The proposal that the second beta-strand of (alpha/beta)8-barrel fold is important from the evolutionary point of view is strongly supported by the increasing trend of the observed beta 2-strand structural similarity for the pairs of (alpha/beta)8-barrel enzymes: alpha-amylase and the alpha-subunit of tryptophan synthase, alpha-amylase and mandelate racemase, and alpha-amylase and cyclodextrin glycosyltransferase. This trend is also in agreement with the existing evolutionary division of the entire family of (alpha/beta)8-barrel proteins. PMID:8762144

  5. Invariant glycines and prolines flanking in loops the strand beta 2 of various (alpha/beta)8-barrel enzymes: a hidden homology?

    PubMed

    Janecek, S

    1996-06-01

    The question of parallel (alpha/beta)8-barrel fold evolution remains unclear, owing mainly to the lack of sequence homology throughout the amino acid sequences of (alpha/beta)8-barrel enzymes. The "classical" approaches used in the search for homologies among (alpha/beta)8-barrels (e.g., production of structurally based alignments) have yielded alignments perfect from the structural point of view, but the approaches have been unable to reveal the homologies. These are proposed to be "hidden" in (alpha/beta)8-barrel enzymes. The term "hidden homology" means that the alignment of sequence stretches proposed to be homologous need not be structurally fully satisfactory. This is due to the very long evolutionary history of all (alpha/beta)8-barrels. This work identifies so-called hidden homology around the strand beta 2 that is flanked by loops containing invariant glycines and prolines in 17 different (alpha/beta)8-barrel enzymes, i.e., roughly in half of all currently known (alpha/beta)8-barrel proteins. The search was based on the idea that a conserved sequence region of an (alpha/beta)8-barrel enzyme should be more or less conserved also in the equivalent part of the structure of the other enzymes with this folding motif, given their mutual evolutionary relatedness. For this purpose, the sequence region around the well-conserved second beta-strand of alpha-amylase flanked by the invariant glycine and proline (56_GFTAIWITP, Aspergillus oryzae alpha-amylase numbering), was used as the sequence-structural template. The proposal that the second beta-strand of (alpha/beta)8-barrel fold is important from the evolutionary point of view is strongly supported by the increasing trend of the observed beta 2-strand structural similarity for the pairs of (alpha/beta)8-barrel enzymes: alpha-amylase and the alpha-subunit of tryptophan synthase, alpha-amylase and mandelate racemase, and alpha-amylase and cyclodextrin glycosyltransferase. This trend is also in agreement with the existing evolutionary division of the entire family of (alpha/beta)8-barrel proteins.

  6. Creation of active TIM barrel enzymes through genetic fusion of half-barrel domain constructs derived from two distantly related glycosyl hydrolases.

    PubMed

    Sharma, Prerna; Kaila, Pallavi; Guptasarma, Purnananda

    2016-12-01

    Diverse unrelated enzymes that adopt the beta/alpha (or TIM) barrel topology display similar arrangements of beta/alpha units placed in a radial eight-fold symmetry around the barrel's axis. The TIM barrel was originally thought to be a single structural domain; however, it is now thought that TIM barrels arose from duplication and fusion of smaller half-barrels consisting of four beta/alpha units. We describe here the design, expression and purification, as well as characterization of folding, activity and stability, of chimeras of two TIM barrel glycosyl hydrolases, made by fusing different half-barrel domains derived from an endoglucanase from Clostridium cellulolyticum, CelCCA and a beta-glucosidase from Pyrococcus furiosus, CelB. We show that after refolding following purification from inclusion bodies, the two half-barrel fusion chimeras (CelCCACelB and CelBCelCCA) display catalytic activity although they assemble into large soluble oligomeric aggregated species containing chains of mixed beta and alpha structure. CelBCelCCA displays hyperthermophile-like structural stability as well as significant stability to chemical denaturation (C m of 2.6 m guanidinium hydrochloride), whereas CelCCACelB displays mesophile-like stability (T m of ~ 71 °C). The endoglucanase activities of both chimeras are an order of magnitude lower than those of CelB or CelCCA, whereas the beta-glucosidase activity of CelBCelCCA is about two orders of magnitude lower than that of CelB. The chimera CelCCACelB shows no beta-glucosidase activity. Our results demonstrate that half-barrel domains from unrelated sources can fold, assemble and function, with scope for improvement. Pyrococcus furiosus beta-glucosidase (CelB, EC: 3.2.1.21). Clostridium cellulolyticum endoglucanase A (CelCCA, EC: 3.2.1.4). © 2016 Federation of European Biochemical Societies.

  7. Assembly of 5.5-Meter Diameter Developmental Barrel Segments for the Ares I Upper Stage

    NASA Technical Reports Server (NTRS)

    Carter, Robert W.

    2011-01-01

    Full scale assembly welding of Ares I Upper Stage 5.5-Meter diameter cryogenic tank barrel segments has been performed at the Marshall Space Flight Center (MSFC). One full-scale developmental article produced under the Ares 1 Upper Stage project is the Manufacturing Demonstration Article (MDA) Barrel. This presentation will focus on the welded assembly of this barrel section, and associated lessons learned. Among the MDA articles planned on the Ares 1 Program, the Barrel was the first to be completed, primarily because the process of manufacture from piece parts (barrel panels) utilized the most mature friction stir process planned for use on the Ares US program: Conventional fixed pin Friction Stir Welding (FSW). This process is in use on other space launch systems, including the Shuttle s External Tank, the Delta IV common booster core, the Delta II, and the Atlas V rockets. The goals for the MDA Barrel development were several fold: 1) to prove out Marshall Space Flight Center s new Vertical Weld Tool for use in manufacture of cylindrical barrel sections, 2) to serve as a first run for weld qualification to a new weld specification, and 3) to provide a full size cylindrical section for downstream use in precision cleaning and Spray-on Foam Insulation development. The progression leading into the welding of the full size barrel included sub scale panel welding, subscale cylinder welding, a full length confidence weld, and finally, the 3 seamed MDA barrel processing. Lessons learned on this MDA program have been carried forward into the production tooling for the Ares 1 US Program, and in the use of the MSFC VWT in processing other large scale hardware, including two 8.4 meter diameter Shuttle External Tank barrel sections that are currently being used in structural analysis to validate shell buckling models.

  8. The structure of the β-barrel assembly machinery complex

    DOE PAGES

    Bakelar, Jeremy; Buchanan, Susan K.; Noinaj, Nicholas

    2016-01-08

    β-Barrel outer membrane proteins (OMPs) are found in the outer membranes of Gram-negative bacteria and are essential for nutrient import, signaling, and adhesion. A 200-kilodalton five-component complex called the β-barrel assembly machinery (BAM) complex has been implicated in the biogenesis of OMPs. In this paper, we report the structure of the BAM complex from Escherichia coli, revealing that binding of BamCDE modulates the conformation of BamA, the central component, which may serve to regulate the BAM complex. The periplasmic domain of BamA was in a closed state that prevents access to the barrel lumen, which indicates substrate OMPs may notmore » be threaded through the barrel during biogenesis. Finally and further, conformational shifts in the barrel domain lead to opening of the exit pore and rearrangement at the lateral gate.« less

  9. The structure of the β-barrel assembly machinery complex

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bakelar, Jeremy; Buchanan, Susan K.; Noinaj, Nicholas

    β-Barrel outer membrane proteins (OMPs) are found in the outer membranes of Gram-negative bacteria and are essential for nutrient import, signaling, and adhesion. A 200-kilodalton five-component complex called the β-barrel assembly machinery (BAM) complex has been implicated in the biogenesis of OMPs. In this paper, we report the structure of the BAM complex from Escherichia coli, revealing that binding of BamCDE modulates the conformation of BamA, the central component, which may serve to regulate the BAM complex. The periplasmic domain of BamA was in a closed state that prevents access to the barrel lumen, which indicates substrate OMPs may notmore » be threaded through the barrel during biogenesis. Finally and further, conformational shifts in the barrel domain lead to opening of the exit pore and rearrangement at the lateral gate.« less

  10. System for supporting a bundled tube fuel injector within a combustor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    LeBegue, Jeffrey Scott; Melton, Patrick Benedict; Westmoreland, III, James Harold

    A combustor includes an end cover having an outer side and an inner side, an outer barrel having a forward end that is adjacent to the inner side of the end cover and an aft end that is axially spaced from the forward end. An inner barrel is at least partially disposed concentrically within the outer barrel and is fixedly connected to the outer barrel. A fluid conduit extends downstream from the end cover. A first bundled tube fuel injector segment is disposed concentrically within the inner barrel. The bundled tube fuel injector segment includes a fuel plenum that ismore » in fluid communication with the fluid conduit and a plurality of parallel tubes that extend axially through the fuel plenum. The bundled tube fuel injector segment is fixedly connected to the inner barrel.« less

  11. Cobalt-Base Alloy Gun Barrel Study

    DTIC Science & Technology

    2014-07-01

    Cobalt-Base Alloy Gun Barrel Study by William S. de Rosset and Jonathan S. Montgomery ARL-RP-0491 July 2014 A reprint...21005-5069 ARL-RP-0491 July 2014 Cobalt-Base Alloy Gun Barrel Study William S. de Rosset and Jonathan S. Montgomery Weapons and Materials... Gun Barrel Study 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) William S. de Rosset and Jonathan S. Montgomery

  12. Cooling of weapons with graphite foam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klett, James W.; Trammell, Michael P.

    Disclosed are examples of an apparatus for cooling a barrel 12 of a firearm 10 and examples of a cooled barrel assembly 32 for installation into an existing firearm 10. When assembled with the barrel 12, a contact surface 16 of a shell 14 is proximate to, and in thermal communication with, the outer surface of the barrel 18. The shell 14 is formed of commercially available or modified graphite foam.

  13. Assembly of the β-Barrel Outer Membrane Proteins in Gram-Negative Bacteria, Mitochondria, and Chloroplasts

    PubMed Central

    Misra, Rajeev

    2012-01-01

    In the last decade, there has been an explosion of publications on the assembly of β-barrel outer membrane proteins (OMPs), which carry out diverse cellular functions, including solute transport, protein secretion, and assembly of protein and lipid components of the outer membrane. Of the three outer membrane model systems—Gram-negative bacteria, mitochondria and chloroplasts—research on bacterial and mitochondrial systems has so far led the way in dissecting the β-barrel OMP assembly pathways. Many exciting discoveries have been made, including the identification of β-barrel OMP assembly machineries in bacteria and mitochondria, and potentially the core assembly component in chloroplasts. The atomic structures of all five components of the bacterial β-barrel assembly machinery (BAM) complex, except the β-barrel domain of the core BamA protein, have been solved. Structures reveal that these proteins contain domains/motifs known to facilitate protein-protein interactions, which are at the heart of the assembly pathways. While structural information has been valuable, most of our current understanding of the β-barrel OMP assembly pathways has come from genetic, molecular biology, and biochemical analyses. This paper provides a comparative account of the β-barrel OMP assembly pathways in Gram-negative bacteria, mitochondria, and chloroplasts. PMID:27335668

  14. Effect of extrusion conditions on the physico-chemical properties and in vitro protein digestibility of canola meal.

    PubMed

    Zhang, Bo; Liu, Guo; Ying, Danyang; Sanguansri, Luz; Augustin, Mary Ann

    2017-10-01

    Canola meal has potential as a high protein food ingredient. The extrusion-induced changes in color, pH, extractable protein and in vitro protein digestibility of canola meal under different extrusion conditions was assessed. The extrusion barrel moisture (24%, 30% or 36%) and screw kneading block length (0, 30 or 60mm) were used as independent process parameters. Extrusion at high barrel moisture (36%) favored protein aggregation resulting in lower extractable protein compared to extrusion at the lowest barrel moisture (24%). At lower barrel moisture contents (24% and 30%), a longer kneading block length increased extractable protein but this was not the case at 36% barrel moisture. Canola protein digestibility was improved upon extrusion at 30% barrel moisture but there was no significant change at lower (24%) or higher (36%) barrel moisture. The kneading block length of the screw had no significant effect on the canola protein digestibility within the same barrel moisture level. The relationship between the physico-chemical parameters and in vitro digestibility was examined. This study highlighted the complex interplay of extrusion processing variables that affect protein degradation and the interaction of components, with consequent effects on protein digestibility. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Nuclear reactor downcomer flow deflector

    DOEpatents

    Gilmore, Charles B [Greensburg, PA; Altman, David A [Pittsburgh, PA; Singleton, Norman R [Murrysville, PA

    2011-02-15

    A nuclear reactor having a coolant flow deflector secured to a reactor core barrel in line with a coolant inlet nozzle. The flow deflector redirects incoming coolant down an annulus between the core barrel and the reactor vessel. The deflector has a main body with a front side facing the fluid inlet nozzle and a rear side facing the core barrel. The rear side of the main body has at least one protrusion secured to the core barrel so that a gap exists between the rear side of the main body adjacent the protrusion and the core barrel. Preferably, the protrusion is a relief that circumscribes the rear side of the main body.

  16. Evolutions of volatile sulfur compounds of Cabernet Sauvignon wines during aging in different oak barrels.

    PubMed

    Ye, Dong-Qing; Zheng, Xiao-Tian; Xu, Xiao-Qing; Wang, Yun-He; Duan, Chang-Qing; Liu, Yan-Lin

    2016-07-01

    The evolution of volatile sulfur compounds (VSCs) in Cabernet Sauvignon wines from seven regions of China during maturation in oak barrels was investigated. The barrels were made of different wood grains (fine and medium) and toasting levels (light and medium). Twelve VSCs were quantified by GC/FPD, with dimethyl sulfide (DMS) and methionol exceeding their sensory thresholds. Most VSCs tended to decline during the aging, while DMS was found to increase. After one year aging, the levels of DMS, 2-methyltetrahy-drothiophen-3-one and sulfur-containing esters were lower in the wines aged in oak barrels than in stainless steel tanks. The wood grain and toasting level of oak barrels significantly influenced the concentration of S-methyl thioacetate and 2-methyltetrahy-drothiophen-3-one. This study reported the evolution of VSCs in wines during oak barrel aging for the first time and evaluated the influence of barrel types, which would provide wine-makers with references in making proposals about wine aging. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Assembly of β-barrel proteins in the mitochondrial outer membrane.

    PubMed

    Höhr, Alexandra I C; Straub, Sebastian P; Warscheid, Bettina; Becker, Thomas; Wiedemann, Nils

    2015-01-01

    Mitochondria evolved through endosymbiosis of a Gram-negative progenitor with a host cell to generate eukaryotes. Therefore, the outer membrane of mitochondria and Gram-negative bacteria contain pore proteins with β-barrel topology. After synthesis in the cytosol, β-barrel precursor proteins are first transported into the mitochondrial intermembrane space. Folding and membrane integration of β-barrel proteins depend on the mitochondrial sorting and assembly machinery (SAM) located in the outer membrane, which is related to the β-barrel assembly machinery (BAM) in bacteria. The SAM complex recognizes β-barrel proteins by a β-signal in the C-terminal β-strand that is required to initiate β-barrel protein insertion into the outer membrane. In addition, the SAM complex is crucial to form membrane contacts with the inner mitochondrial membrane by interacting with the mitochondrial contact site and cristae organizing system (MICOS) and shares a subunit with the endoplasmic reticulum-mitochondria encounter structure (ERMES) that links the outer mitochondrial membrane to the endoplasmic reticulum (ER). Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Research on vibration characteristics of gun barrel based on contact model

    NASA Astrophysics Data System (ADS)

    Zhao, Yang; Zhou, Qizheng; Yue, Pengfei

    2017-04-01

    In order to study vibration characteristics of the gun barrel under the action of moving projectile, the gun barrel is simplified to cross sectional cantilever beam such as Euler. Considering contact conditions of inertia effect and projectile with the gun barrel, the equation of lateral vibration of the gun barrel is established under the projectile-gun coupling effect; the modal analysis method is used to give the analytic solutions of equation series. The effect of the motion parameters the projectile on the vibration of gun barrel is discussed, and characteristics of vibration of gun barrel are further studied under two conditions of repeating and projectile with mass eccentricity. The research results show that reasonable control of the acceleration of the projectile in the gun bore, and reduction of projectile mass eccentricity can help reduce the muzzle vibration at the gun firing. The research results can provide reference for overall design of the gun, and the modeling and analysis method used in the paper can be promoted for the solution of vibration of other related projects under the moving excitation.

  19. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-12-08

    Liftoff! A balloon begins to rise over the brand new Halley VI Research Station, which had its grand opening in February 2013. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  20. Recent evidence for evolution of the genetic code

    NASA Technical Reports Server (NTRS)

    Osawa, S.; Jukes, T. H.; Watanabe, K.; Muto, A.

    1992-01-01

    The genetic code, formerly thought to be frozen, is now known to be in a state of evolution. This was first shown in 1979 by Barrell et al. (G. Barrell, A. T. Bankier, and J. Drouin, Nature [London] 282:189-194, 1979), who found that the universal codons AUA (isoleucine) and UGA (stop) coded for methionine and tryptophan, respectively, in human mitochondria. Subsequent studies have shown that UGA codes for tryptophan in Mycoplasma spp. and in all nonplant mitochondria that have been examined. Universal stop codons UAA and UAG code for glutamine in ciliated protozoa (except Euplotes octacarinatus) and in a green alga, Acetabularia. E. octacarinatus uses UAA for stop and UGA for cysteine. Candida species, which are yeasts, use CUG (leucine) for serine. Other departures from the universal code, all in nonplant mitochondria, are CUN (leucine) for threonine (in yeasts), AAA (lysine) for asparagine (in platyhelminths and echinoderms), UAA (stop) for tyrosine (in planaria), and AGR (arginine) for serine (in several animal orders) and for stop (in vertebrates). We propose that the changes are typically preceded by loss of a codon from all coding sequences in an organism or organelle, often as a result of directional mutation pressure, accompanied by loss of the tRNA that translates the codon. The codon reappears later by conversion of another codon and emergence of a tRNA that translates the reappeared codon with a different assignment. Changes in release factors also contribute to these revised assignments. We also discuss the use of UGA (stop) as a selenocysteine codon and the early history of the code.

  1. 8. View southwest at the northeastern end of culvert inlet, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. View southwest at the northeastern end of culvert inlet, with canal bank completely removed. Left to right: back of curved wingwall; tops of high inlet barrels; vertical transition wall between high inlet barrels and low interior barrels; tops of low, interior barrels; vertical heartening planks at former canal edge of canal bank. - Delaware & Raritan Canal, Ten Mile Run Culvert, 1.5 miles South of Blackwells Road, East Millstone, Somerset County, NJ

  2. 6. View southwest, culvert inlet with canal bank completely removed. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View southwest, culvert inlet with canal bank completely removed. Left to right: back of headwall; tops of high inlet barrels; vertical transition wall between high inlet barrels and low, interior, inlet barrels; tops of low interior barrels; vertical heartening planks and low cutoff wall along former edge of canal bank; dewatered canal bed. - Delaware & Raritan Canal, Ten Mile Run Culvert, 1.5 miles South of Blackwells Road, East Millstone, Somerset County, NJ

  3. 46th Annual Gun and Missile Systems Conference and Exhibition. Volume 3 - Thursday

    DTIC Science & Technology

    2011-09-01

    Grade Sensors Through Use of Accelerated Aging Principles Mr. Scott Gift 11657 Modeling of the Autofrettage Processes of a Gun Barrel Mr. Sudhir...Emissions Measured on the Outer Portion of a Composite Barrel Ms. Rushie Ghimire GUN & MISSILE SYSTEMS ADDITIONAL AUTHORS GUN & MISSILE SYSTEMS...Transportation – Loading – Gun Fire to Barrel Exit – After Barrel Exit • Passing: Fuze safety devices remain safe; safe for disposal or safe for

  4. Sequential injection gas guns for accelerating projectiles

    DOEpatents

    Lacy, Jeffrey M [Idaho Falls, ID; Chu, Henry S [Idaho Falls, ID; Novascone, Stephen R [Idaho Falls, ID

    2011-11-15

    Gas guns and methods for accelerating projectiles through such gas guns are described. More particularly, gas guns having a first injection port located proximate a breech end of a barrel and a second injection port located longitudinally between the first injection port and a muzzle end of the barrel are described. Additionally, modular gas guns that include a plurality of modules are described, wherein each module may include a barrel segment having one or more longitudinally spaced injection ports. Also, methods of accelerating a projectile through a gas gun, such as injecting a first pressurized gas into a barrel through a first injection port to accelerate the projectile and propel the projectile down the barrel past a second injection port and injecting a second pressurized gas into the barrel through the second injection port after passage of the projectile and to further accelerate the projectile are described.

  5. A radial map of multi-whisker correlation selectivity in the rat barrel cortex

    PubMed Central

    Estebanez, Luc; Bertherat, Julien; Shulz, Daniel E.; Bourdieu, Laurent; Léger, Jean- François

    2016-01-01

    In the barrel cortex, several features of single-whisker stimuli are organized in functional maps. The barrel cortex also encodes spatio-temporal correlation patterns of multi-whisker inputs, but so far the cortical mapping of neurons tuned to such input statistics is unknown. Here we report that layer 2/3 of the rat barrel cortex contains an additional functional map based on neuronal tuning to correlated versus uncorrelated multi-whisker stimuli: neuron responses to uncorrelated multi-whisker stimulation are strongest above barrel centres, whereas neuron responses to correlated and anti-correlated multi-whisker stimulation peak above the barrel–septal borders, forming rings of multi-whisker synchrony-preferring cells. PMID:27869114

  6. Core drilling apparatus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gusman, M.T.; Konstantinov, L.P.; Malkin, B.D.

    1974-04-16

    Mounted on the exterior of a nonrotatable core barrel is an end of a resilient tape, the other end of which extends inward into the barrel and is connected to a device for pulling the tape inward into the barrel. The apparatus also is provided with an arrangement which forms a sleeve from the tape as this is being pulled into the core barrel. During the coring operation, the tape is being pulled inward into the barrel and a sleeve is formed from the tape with the aid of the arrangement to encase and protect the core from disturbance. Themore » coring apparatus is intended for core drilling in soft, unconsolidated, and fractured formations. (3 claims)« less

  7. Ballistics of the 30-06 Rifle Cartridge

    DTIC Science & Technology

    2012-11-30

    manuals for common bullet weights. Hodgdon, Nosler, and Barnes report velocities for 24" barrels . Hornady and Speer report velocoties for 22" barrels ...The data are all for barrels with a twist rate of 1 turn in 10” which is needed to stabilize the heaviest bullets. The higher muzzle velocities...are available that provide 2900 fps for 150 grain bullets, 2800 fps for 165 grain bullets, and 2700 fps for 180 grain bullets (in a 24 inch barrel

  8. Effect of oak wood barrel capacity and utilization time on phenolic and sensorial profile evolution of an Encruzado white wine.

    PubMed

    Nunes, Paulo; Muxagata, Sara; Correia, Ana C; Nunes, Fernando M; Cosme, Fernanda; Jordão, António M

    2017-11-01

    Several studies have reported the influence of diverse winemaking technologies in white wine characteristics. However, the impact of the use of different oak wood barrel capacities and utilization time on the evolution of white wine phenolic content and sensorial characteristics are not usually considered. Thus the aim of this work was to evaluate the effect of oak wood barrel capacity and utilization time on the evolution of phenolic compounds, browning potential index and sensorial profile of an Encruzado white wine. For the 180 aging days considered, the use of new oak wood barrels induced a greater increase in global phenolic composition, including several individual compounds, such as gallic and ellagic acid, independently of the barrel capacity. Tendency for a lesser increase of the browning potential index values was detected for white wines aged in new oak wood barrels. The sensorial profile evolution, showed significant differences only for the aroma descriptors, namely for 'wood aroma' and 'aroma intensity', white wine aged in 225 L new oak wood barrels being the highest scored. The results show that, in general, the use of different capacities and utilization time of oak wood barrels used for white wine aging could play an important role in white wine quality. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  9. Excitatory neuronal connectivity in the barrel cortex

    PubMed Central

    Feldmeyer, Dirk

    2012-01-01

    Neocortical areas are believed to be organized into vertical modules, the cortical columns, and the horizontal layers 1–6. In the somatosensory barrel cortex these columns are defined by the readily discernible barrel structure in layer 4. Information processing in the neocortex occurs along vertical and horizontal axes, thereby linking individual barrel-related columns via axons running through the different cortical layers of the barrel cortex. Long-range signaling occurs within the neocortical layers but also through axons projecting through the white matter to other neocortical areas and subcortical brain regions. Because of the ease of identification of barrel-related columns, the rodent barrel cortex has become a prototypical system to study the interactions between different neuronal connections within a sensory cortical area and between this area and other cortical as well subcortical regions. Such interactions will be discussed specifically for the feed-forward and feedback loops between the somatosensory and the somatomotor cortices as well as the different thalamic nuclei. In addition, recent advances concerning the morphological characteristics of excitatory neurons and their impact on the synaptic connectivity patterns and signaling properties of neuronal microcircuits in the whisker-related somatosensory cortex will be reviewed. In this context, their relationship between the structural properties of barrel-related columns and their function as a module in vertical synaptic signaling in the whisker-related cortical areas will be discussed. PMID:22798946

  10. The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism.

    PubMed

    Goldman, Aaron David; Beatty, Joshua T; Landweber, Laura F

    2016-01-01

    The triosephosphate isomerase (TIM) barrel protein fold is a structurally repetitive architecture that is present in approximately 10% of all enzymes. It is generally assumed that this ubiquity in modern proteomes reflects an essential historical role in early protein-mediated metabolism. Here, we provide quantitative and comparative analyses to support several hypotheses about the early importance of the TIM barrel architecture. An information theoretical analysis of protein structures supports the hypothesis that the TIM barrel architecture could arise more easily by duplication and recombination compared to other mixed α/β structures. We show that TIM barrel enzymes corresponding to the most taxonomically broad superfamilies also have the broadest range of functions, often aided by metal and nucleotide-derived cofactors that are thought to reflect an earlier stage of metabolic evolution. By comparison to other putatively ancient protein architectures, we find that the functional diversity of TIM barrel proteins cannot be explained simply by their antiquity. Instead, the breadth of TIM barrel functions can be explained, in part, by the incorporation of a broad range of cofactors, a trend that does not appear to be shared by proteins in general. These results support the hypothesis that the simple and functionally general TIM barrel architecture may have arisen early in the evolution of protein biosynthesis and provided an ideal scaffold to facilitate the metabolic transition from ribozymes, peptides, and geochemical catalysts to modern protein enzymes.

  11. A Supercomplex Spanning the Inner and Outer Membranes Mediates the Biogenesis of β-Barrel Outer Membrane Proteins in Bacteria.

    PubMed

    Wang, Yan; Wang, Rui; Jin, Feng; Liu, Yang; Yu, Jiayu; Fu, Xinmiao; Chang, Zengyi

    2016-08-05

    β-barrel outer membrane proteins (OMPs) are ubiquitously present in Gram-negative bacteria, mitochondria and chloroplasts, and function in a variety of biological processes. The mechanism by which the hydrophobic nascent β-barrel OMPs are transported through the hydrophilic periplasmic space in bacterial cells remains elusive. Here, mainly via unnatural amino acid-mediated in vivo photo-crosslinking studies, we revealed that the primary periplasmic chaperone SurA interacts with nascent β-barrel OMPs largely via its N-domain but with β-barrel assembly machine protein BamA mainly via its satellite P2 domain, and that the nascent β-barrel OMPs interact with SurA via their N- and C-terminal regions. Additionally, via dual in vivo photo-crosslinking, we demonstrated the formation of a ternary complex involving β-barrel OMP, SurA, and BamA in cells. More importantly, we found that a supercomplex spanning the inner and outer membranes and involving the BamA, BamB, SurA, PpiD, SecY, SecE, and SecA proteins appears to exist in living cells, as revealed by a combined analyses of sucrose-gradient ultra-centrifugation, Blue native PAGE and mass spectrometry. We propose that this supercomplex integrates the translocation, transportation, and membrane insertion events for β-barrel OMP biogenesis. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  12. A Supercomplex Spanning the Inner and Outer Membranes Mediates the Biogenesis of β-Barrel Outer Membrane Proteins in Bacteria*

    PubMed Central

    Wang, Yan; Wang, Rui; Jin, Feng; Liu, Yang; Yu, Jiayu; Fu, Xinmiao; Chang, Zengyi

    2016-01-01

    β-barrel outer membrane proteins (OMPs) are ubiquitously present in Gram-negative bacteria, mitochondria and chloroplasts, and function in a variety of biological processes. The mechanism by which the hydrophobic nascent β-barrel OMPs are transported through the hydrophilic periplasmic space in bacterial cells remains elusive. Here, mainly via unnatural amino acid-mediated in vivo photo-crosslinking studies, we revealed that the primary periplasmic chaperone SurA interacts with nascent β-barrel OMPs largely via its N-domain but with β-barrel assembly machine protein BamA mainly via its satellite P2 domain, and that the nascent β-barrel OMPs interact with SurA via their N- and C-terminal regions. Additionally, via dual in vivo photo-crosslinking, we demonstrated the formation of a ternary complex involving β-barrel OMP, SurA, and BamA in cells. More importantly, we found that a supercomplex spanning the inner and outer membranes and involving the BamA, BamB, SurA, PpiD, SecY, SecE, and SecA proteins appears to exist in living cells, as revealed by a combined analyses of sucrose-gradient ultra-centrifugation, Blue native PAGE and mass spectrometry. We propose that this supercomplex integrates the translocation, transportation, and membrane insertion events for β-barrel OMP biogenesis. PMID:27298319

  13. Identification of Intracellular β-Barrel Residues Involved in Ion Selectivity in the Mechanosensitive Channel of Thermoanaerobacter tengcongensis

    PubMed Central

    Song, Yingcai; Zhang, Bing; Guo, Fei; Yang, Maojun; Li, Yang; Liu, Zhi-Qiang

    2017-01-01

    The mechanosensitive channel of small conductance (MscS) is a bacterial membrane pore that senses membrane tension and protects cells from lysis by releasing osmolytes. MscS is a homoheptameric channel with a cytoplasmic domain with seven portals and a β-barrel opening to the cytoplasm. TtMscS, an MscS channel from Thermoanaerobacter tengcongensis, is an anion-selective channel. A previous study from our laboratory has defined the crucial role of β-barrel in the anion selectivity of TtMscS (Zhang et al., 2012). However, the mechanistic details by which the β-barrel determines anion selectivity remain unclear. Here, using mutagenesis and patch-clamp recordings, we investigated the function and structural correlations between β-barrels and the anion selectivity of TtMscS at the atomic level. Our results indicated that mutation of V274, a residue at the center of the inner wall of the β-barrel in TtMscS, caused the anion selectivity of TtMscS reverse to cation selectivity. Moreover, the electrostatic potential (T272) and physical size (L276) of residues in the inner wall of β-barrel also determine the anion selectivity of TtMscS. In summary, the present study confirmed that the β-barrel region of TtMscS acts as a “selective filter” that renders TtMscS anion selectivity. PMID:29118717

  14. Cobalamin-Independent Methionine Synthase (MetE): A Face-to-Face Double Barrel that Evolved by Gene Duplication

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pejcha, Robert; Ludwig, Martha L.

    2010-03-08

    Cobalamin-independent methionine synthase (MetE) catalyzes the transfer of a methyl group from methyltetrahydrofolate to L-homocysteine (Hcy) without using an intermediate methyl carrier. Although MetE displays no detectable sequence homology with cobalamin-dependent methionine synthase (MetH), both enzymes require zinc for activation and binding of Hcy. Crystallographic analyses of MetE from T. maritima reveal an unusual dual-barrel structure in which the active site lies between the tops of the two ({beta}{alpha}){sub 8} barrels. The fold of the N-terminal barrel confirms that it has evolved from the C-terminal polypeptide by gene duplication; comparisons of the barrels provide an intriguing example of homologous domainmore » evolution in which binding sites are obliterated. The C-terminal barrel incorporates the zinc ion that binds and activates Hcy. The zinc-binding site in MetE is distinguished from the (Cys){sub 3}Zn site in the related enzymes, MetH and betaine-homocysteine methyltransferase, by its position in the barrel and by the metal ligands, which are histidine, cysteine, glutamate, and cysteine in the resting form of MetE. Hcy associates at the face of the metal opposite glutamate, which moves away from the zinc in the binary E {center_dot} Hcy complex. The folate substrate is not intimately associated with the N-terminal barrel; instead, elements from both barrels contribute binding determinants in a binary complex in which the folate substrate is incorrectly oriented for methyl transfer. Atypical locations of the Hcy and folate sites in the C-terminal barrel presumably permit direct interaction of the substrates in a ternary complex. Structures of the binary substrate complexes imply that rearrangement of folate, perhaps accompanied by domain rearrangement, must occur before formation of a ternary complex that is competent for methyl transfer.« less

  15. Final Report of the Rifling Profile Push Test

    DTIC Science & Technology

    2007-06-01

    barrel lands through the copper alloy jacket, as shown in figure 6. As a result, compression of the jacket material above the steel core will occur...resistance pressure of the M855 projectile in an M16A2 barrel section. The M855 test projectiles were tested in a 2 × 2 matrix, two different M16A2 barrel ...1 Figure 2. M16A2 barrel machined section. The units of measure are in cm.................................2 Figure 3

  16. COUNTERMEASURE: Army Ground Risk-Management Information. Volume 24, Number 3

    DTIC Science & Technology

    2003-03-01

    damp rag, or a dry, clean cloth. Underwear crew members and maintenance personnel must should be changed frequently and foot powder wear gloves to...only p rolem oh the unlined barrel due to the probability of firing ugly things can happen with unlined barrels. If SLAP ammo. SLAP ammo will cause the...unlined you chamber a SLAP round in an unlined barrel barrel to wear significantly faster than the lined and don’t fire the round, there is a good

  17. The TonB-dependent Transporter FhuA in Planar Lipid Bilayers: partial exit of its plug from the barrel

    PubMed Central

    Udho, Eshwar; Jakes, Karen S.; Finkelstein, Alan

    2012-01-01

    TonB-dependent transporters (TBDTs), which transport iron-chelating siderophores and vitamin B12 across the outer membrane of gram negative bacteria, share a conserved architecture of a 22-stranded beta-barrel with an amino-terminal plug domain occluding the barrel. We previously reported that we could induce TBDTs to reversibly open in planar lipid bilayers via the use of urea and that these channels were responsive to physiological concentrations of ligands. Here we report that in the presence of urea, trypsin can cleave the amino-terminal 67 residues of the plug of the TonB-dependent transporter FhuA, as assessed by gel shift and mass spectrometry assays. On the bilayer, trypsin treatment in the presence of urea resulted in the induced conductance no longer being reversed upon removal of urea, suggesting that urea opens intact FhuA channels by pulling the plug at least partly out of the barrel, and that removal of the urea then allows reinsertion of the plug into the barrel. When expressed separately, the FhuA plug domain was found to be a mostly unfolded structure that was able to occlude isolated FhuA beta-barrels inserted into the membrane. Thus, although folded in the barrel, the plug need not be folded upon exiting the barrel. The rate of insertion of the beta-barrels into the membrane was tremendously increased in the presence of an osmotic gradient provided by either urea or glycerol. Negative staining electron microscopy showed that FhuA in a detergent solution formed vesicles, thus explaining why an osmotic gradient promoted the insertion of FhuA into membranes. PMID:22846061

  18. Water-Soluble Pd8L4 Self-assembled Molecular Barrel as an Aqueous Carrier for Hydrophobic Curcumin.

    PubMed

    Bhat, Imtiyaz Ahmad; Jain, Ruchi; Siddiqui, Mujahuddin M; Saini, Deepak K; Mukherjee, Partha Sarathi

    2017-05-01

    A tetrafacial water-soluble molecular barrel (1) was synthesized by coordination driven self-assembly of a symmetrical tetrapyridyl donor (L) with a cis-blocked 90° acceptor [cis-(en)Pd(NO 3 ) 2 ] (en = ethane-1,2-diamine). The open barrel structure of (1) was confirmed by single crystal X-ray diffraction. The presence of a hydrophobic cavity with large windows makes it an ideal candidate for encapsulation and carrying hydrophobic drug like curcumin in an aqueous medium. The barrel (1) encapsulates curcumin inside its molecular cavity and protects highly photosensitive curcumin from photodegradation. The photostability of encapsulated curcumin is due to the absorption of a high proportion of the incident photons by the aromatic walls of 1 with a high absorption cross-sectional area, which helps the walls to shield the guest even against sunlight/UV radiations. As compared to free curcumin in water, we noticed a significant increase in solubility as well as cellular uptake of curcumin upon encapsulation inside the water-soluble molecular barrel (1) in aqueous medium. Fluorescence imaging confirmed that curcumin was delivered into HeLa cancer cells by the aqueous barrel (1) with the retention of its potential anticancer activity. While free curcumin is inactive toward cancer cells in aqueous medium at room temperature due to negligible solubility, the determined IC 50 value of ∼14 μM for curcumin in aqueous medium in the presence of the barrel (1) reflects the efficiency of the barrel as a potential curcumin carrier in aqueous medium without any other additives. Thus, two major challenges of increasing the bioavailability and stability of curcumin in aqueous medium even in the presence of UV light have been addressed by using a new supramolecular water-soluble barrel (1) as a drug carrier.

  19. 49 CFR 178.510 - Standards for wooden barrels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Standards for wooden barrels. 178.510 Section 178.510 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS...-bulk Performance-Oriented Packaging Standards § 178.510 Standards for wooden barrels. (a) The following...

  20. 49 CFR 178.510 - Standards for wooden barrels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Standards for wooden barrels. 178.510 Section 178.510 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS... PACKAGINGS Non-bulk Performance-Oriented Packaging Standards § 178.510 Standards for wooden barrels. (a) The...

  1. Real-time monitoring of barrel thickness and barrel/screw separation using ultrasound

    NASA Astrophysics Data System (ADS)

    Jen, Cheng-Kuei; Zun, Zhigang; Kobayashi, Makiko

    2005-03-01

    Ultrasonic sensors together with a fast data acquisition system have been used to monitor the barrel thickness and barrel/screw separation during low-density polyethylene as well as high-density polyethylene extrusion in 30 mm and 50 mm twin-screw extruders. The sensors include sol-gel sprayed high temperature (HT) piezoelectric thick ceramic film ultrasonic transducers (UTs), stand-alone HTUTs and air-cooled buffer rod type sensors consisting of a room temperature UT and a non-clad or clad buffer rod to which the room temperature UT is attached. The installation and use of these sensors are non-intrusive to the extruder and non-destructive to the polymers being processed. This study has demonstrated the capability of appropriately designed ultrasonic sensors in monitoring the barrel and screw integrity at the melting, mixing and pumping zones of the extruder via barrel or flange. The merits and limitations of these sensors are discussed. The measurement speed and analysis of the sensitivity for quantitative wear measurements are also presented.

  2. Autotransporter structure reveals intra-barrel cleavage followed by conformational changes.

    PubMed

    Barnard, Travis J; Dautin, Nathalie; Lukacik, Petra; Bernstein, Harris D; Buchanan, Susan K

    2007-12-01

    Autotransporters are virulence factors produced by Gram-negative bacteria. They consist of two domains, an N-terminal 'passenger' domain and a C-terminal beta-domain. beta-domains form beta-barrel structures in the outer membrane while passenger domains are translocated into the extracellular space. In some autotransporters, the two domains are separated by proteolytic cleavage. Using X-ray crystallography, we solved the 2.7-A structure of the post-cleavage state of the beta-domain of EspP, an autotransporter produced by Escherichia coli strain O157:H7. The structure consists of a 12-stranded beta-barrel with the passenger domain-beta-domain cleavage junction located inside the barrel pore, approximately midway between the extracellular and periplasmic surfaces of the outer membrane. The structure reveals an unprecedented intra-barrel cleavage mechanism and suggests that two conformational changes occur in the beta-domain after cleavage, one conferring increased stability on the beta-domain and another restricting access to the barrel pore.

  3. Effect of Friction on Barreling during cold Upset Forging of Aluminium 6082 Alloy Solid cylinders

    NASA Astrophysics Data System (ADS)

    Priyadarshini, Amrita; Kiran, C. P.; Suresh, K.

    2018-03-01

    Friction is one of the significant factors in forging operations since it affects metal flow in the die, forming load, strain distribution, tool and die life, surface quality of the product etc. In upset forging, the frictional forces at the die-workpiece interface oppose the outward flow of the material due to which the specimen develops a barrel shape. As a result, the deformation becomes non-uniform or inhomogeneous which is undesirable. Barreling can be reduced by applying effective lubricant on the surface of the platens. The objective of the present work is to study experimentally the effect of various frictional conditions (dry, grease, mineral oil) on barreling during upset forging of aluminum 6082 solid cylinders of different aspect ratio (length/diameter: 0.5, 0.75, 1). The friction coefficients are determined using the ring compression test. Curvature of barrel is determined based on the assumption that the curvature of the barrel follows the geometry of circular arc.

  4. Consumer demand for green stormwater management technology in an urban setting: The case of Chicago rain barrels

    NASA Astrophysics Data System (ADS)

    Ando, Amy W.; Freitas, Luiz P. C.

    2011-12-01

    Hydrological disruption and water pollution from urbanization can be reduced if households in urban areas adopt decentralized storm water controls. We study a citywide municipal subsidized rain-barrel program in the third biggest city in the United States, Chicago, to explore what factors influence whether households purchase this sort of green storm water management technology in an urban setting. Specifically, we regress census-tract level data on the number of rain barrels adopted in different parts of the city on socioeconomic variables, data on local flood frequency, and features of the housing stock. We find that rain-barrel purchases are not correlated with local levels of flooding, even though city residents were told by program managers that rain barrels could alleviate local flooding. Instead, rain barrels are heavily concentrated in places with high-income attitudinally green populations. We do find more rain barrels were adopted in places close to rain-barrel distribution points and near sites of hydrological information campaigns; thus, policy makers might increase green-technology adoption in areas where they can do the most good by reducing transaction costs and providing education programs to those areas. Finally, our results indicate that owner occupancy is positively correlated with green-technology adoption. Low-rise rental housing may have inefficiently low levels of adoption, such that city managers might want to develop programs to encourage storm water management investments by landlords who do not live in their own properties.

  5. Globally intertwined evolutionary history of giant barrel sponges

    NASA Astrophysics Data System (ADS)

    Swierts, Thomas; Peijnenburg, Katja T. C. A.; de Leeuw, Christiaan A.; Breeuwer, Johannes A. J.; Cleary, Daniel F. R.; de Voogd, Nicole J.

    2017-09-01

    Three species of giant barrel sponge are currently recognized in two distinct geographic regions, the tropical Atlantic and the Indo-Pacific. In this study, we used molecular techniques to study populations of giant barrel sponges across the globe and assessed whether the genetic structure of these populations agreed with current taxonomic consensus or, in contrast, whether there was evidence of cryptic species. Using molecular data, we assessed whether giant barrel sponges in each oceanic realm represented separate monophyletic lineages. Giant barrel sponges from 17 coral reef systems across the globe were sequenced for mitochondrial (partial CO1 and ATP6 genes) and nuclear (ATPsβ intron) DNA markers. In total, we obtained 395 combined sequences of the mitochondrial CO1 and ATP6 markers, which resulted in 17 different haplotypes. We compared a phylogenetic tree constructed from 285 alleles of the nuclear intron ATPsβ to the 17 mitochondrial haplotypes. Congruent patterns between mitochondrial and nuclear gene trees of giant barrel sponges provided evidence for the existence of multiple reproductively isolated species, particularly where they occurred in sympatry. The species complexes in the tropical Atlantic and the Indo-Pacific, however, do not form separate monophyletic lineages. This rules out the scenario that one species of giant barrel sponge developed into separate species complexes following geographic separation and instead suggests that multiple species of giant barrel sponges already existed prior to the physical separation of the Indo-Pacific and tropical Atlantic.

  6. 40 CFR 52.987 - Control of hydrocarbon emissions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... control systems on a 37,500 barrel capacity crude oil storage tank at Cities Service Pipeline Company, Oil... a 25,000 barrel capacity crude oil storage tank at Cities Service Pipeline Company, Haynesville... barrel capacity crude oil storage tank at Cities Service Pipeline Company, Summerfield, Louisiana with...

  7. 40 CFR 52.987 - Control of hydrocarbon emissions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... control systems on a 37,500 barrel capacity crude oil storage tank at Cities Service Pipeline Company, Oil... a 25,000 barrel capacity crude oil storage tank at Cities Service Pipeline Company, Haynesville... barrel capacity crude oil storage tank at Cities Service Pipeline Company, Summerfield, Louisiana with...

  8. 40 CFR 52.987 - Control of hydrocarbon emissions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... control systems on a 37,500 barrel capacity crude oil storage tank at Cities Service Pipeline Company, Oil... a 25,000 barrel capacity crude oil storage tank at Cities Service Pipeline Company, Haynesville... barrel capacity crude oil storage tank at Cities Service Pipeline Company, Summerfield, Louisiana with...

  9. Edge multi-energy soft x-ray diagnostic in Experimental Advanced Superconducting Tokamak

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Y. L.; Xu, G. S.; Wan, B. N.

    A multi-energy soft x-ray (ME-SXR) diagnostic has been built for electron temperature profile in the edge plasma region in Experimental Advanced Superconducting Tokamak (EAST) after two rounds of campaigns. Originally, five preamplifiers were mounted inside the EAST vacuum vessel chamber attached to five vertically stacked compact diode arrays. A custom mechanical structure was designed to protect the detectors and electronics under constraints of the tangential field of view for plasma edge and the allocation of space. In the next experiment, the mechanical structure was redesigned with a barrel structure to absolutely isolate it from the vacuum vessel. Multiple shielding structuresmore » were mounted at the pinhole head to protect the metal foils from lithium coating. The pre-amplifiers were moved to the outside of the vacuum chamber to avoid introducing interference. Twisted copper cooling tube was embedded into the back-shell near the diode to limit the temperature of the preamplifiers and diode arrays during vacuum vessel baking when the temperature reached 150 °C. Electron temperature profiles were reconstructed from ME-SXR measurements using neural networks.« less

  10. Methodology for the Determination of the Photon Detection Efficiency of Large-Area Multi-Pixel Photon Counters

    NASA Astrophysics Data System (ADS)

    Beattie, T.; Lolos, G. J.; Papandreou, Z.; Semenov, A. Yu.; Teigrob, L. A.

    2015-08-01

    Large-area, multi-pixel photon counters will be used for the electromagnetic Barrel Calorimeter of the GlueX experiment at Jefferson Lab. These photo sensors are based on a 3 ×3 mm2 cell populated by 50 μm pixels, with 16 such cells tiled in a 4 ×4 arrangement in the array. The 16 cells are summed electronically and the signals are amplified. The photon detection efficiency of a group of first-article units at room temperature under conditions similar to those of the experiment was extracted to be (28 ±2(stat) ±2(syst))%, by employing an analysis methodology based on Poisson statistics carried out on the summed energy signals from the units.

  11. 15 CFR 240.5 - Required marking.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE STANDARDS FOR BARRELS BARRELS AND OTHER CONTAINERS FOR LIME § 240.5 Required marking. (a) The lettering required upon barrels of lime by section 2 of the law shall... lime and where manufactured, and, if imported, the name of the country from which it is imported, shall...

  12. 75 FR 6706 - In the Matter of Certain Foldable Stools; Notice of Commission Decision Not To Review an Initial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ... Distributing and Crate & Barrel with ``LTD Commodities, LLC, d/b/a abc Distributing'' and ``Euromarket Designs... of investigation named several respondents including the following: abc Distributing Inc. (``abc Distributing'') of Bannockburn, Illinois; Crate & Barrel, Inc. (``Crate & Barrel'') of Northbrook, Illinois...

  13. 27 CFR 25.141 - Barrels and kegs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Barrels and kegs. 25.141 Section 25.141 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Marks, Brands, and Labels § 25.141 Barrels and kegs. (a) General...

  14. 10. OBLIQUE VIEW, PORTION OF SPANDREL WALL AND ARCH BARREL, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. OBLIQUE VIEW, PORTION OF SPANDREL WALL AND ARCH BARREL, FROM SOUTHEAST, SHOWING INTRADOS AND EXTRADOS, JUNCTURE OF BRICK BARREL AND CUT STONE MASONRY FACING STONES, TIE ROD CAPS, AND CONCRETE PARAPET EXTENSION - Boston Street Bridge, Spanning Harris Creek Sewer at Boston Street, Baltimore, Independent City, MD

  15. Parallel beta/alpha-barrels of alpha-amylase, cyclodextrin glycosyltransferase and oligo-1,6-glucosidase versus the barrel of beta-amylase: evolutionary distance is a reflection of unrelated sequences.

    PubMed

    Janecek, S

    1994-10-17

    The structures of functionally related beta/alpha-barrel starch hydrolases, alpha-amylase, beta-amylase, cyclodextrin glycosyltransferase and oligo-1,6-glucosidase, are discussed, their mutual sequence similarities being emphasized. Since these enzymes (except for beta-amylase) along with the predicted set of more than ten beta/alpha-barrels from the alpha-amylase enzyme superfamily fulfil the criteria characteristic of the products of divergent evolution, their unrooted distance tree is presented.

  16. Role of Hydrophobic Clusters and Long-Range Contact Networks in the Folding of (α/β)8 Barrel Proteins

    PubMed Central

    Selvaraj, S.; Gromiha, M. Michael

    2003-01-01

    Analysis on the three dimensional structures of (α/β)8 barrel proteins provides ample light to understand the factors that are responsible for directing and maintaining their common fold. In this work, the hydrophobically enriched clusters are identified in 92% of the considered (α/β)8 barrel proteins. The residue segments with hydrophobic clusters have high thermal stability. Further, these clusters are formed and stabilized through long-range interactions. Specifically, a network of long-range contacts connects adjacent β-strands of the (α/β)8 barrel domain and the hydrophobic clusters. The implications of hydrophobic clusters and long-range networks in providing a feasible common mechanism for the folding of (α/β)8 barrel proteins are proposed. PMID:12609894

  17. Hierarchical CoP/Ni 5 P 4 /CoP microsheet arrays as a robust pH-universal electrocatalyst for efficient hydrogen generation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mishra, Ishwar Kumar; Zhou, Haiqing; Sun, Jingying

    Exceptional Pt-like electrocatalytic activity was achieved in a sandwich-like catalyst of CoP/Ni 5 P 4 /CoP microsheet arrays for pH-universal hydrogen evolution through simply wrapping Ni 5 P 4 nanosheet arrays in CoP nanoparticles.

  18. Hierarchical CoP/Ni 5 P 4 /CoP microsheet arrays as a robust pH-universal electrocatalyst for efficient hydrogen generation

    DOE PAGES

    Mishra, Ishwar Kumar; Zhou, Haiqing; Sun, Jingying; ...

    2018-01-01

    Exceptional Pt-like electrocatalytic activity was achieved in a sandwich-like catalyst of CoP/Ni 5 P 4 /CoP microsheet arrays for pH-universal hydrogen evolution through simply wrapping Ni 5 P 4 nanosheet arrays in CoP nanoparticles.

  19. Fabrication and Tests of M240 Machine Gun Barrels Lined with Stellite 25

    DTIC Science & Technology

    2016-04-01

    ARL-TR-7662 ● APR 2016 US Army Research Laboratory Fabrication and Tests of M240 Machine Gun Barrels Lined with Stellite 25...Fabrication and Tests of M240 Machine Gun Barrels Lined with Stellite 25 by William S de Rosset and Sean Fudger Weapons and Materials Research...

  20. Processing of Niobium-Lined M240 Machine Gun Barrels

    DTIC Science & Technology

    2014-11-01

    different materials (the gun steel and the niobium liner). A large chunk of the niobium liner in barrel 2 was torn away from the end of the liner at...it to increase the frictional bond between the liner and gun steel . The barrels with liners were hammer forged by FN. FN experienced some...

  1. Lhx2 Expression in Postmitotic Cortical Neurons Initiates Assembly of the Thalamocortical Somatosensory Circuit.

    PubMed

    Wang, Chia-Fang; Hsing, Hsiang-Wei; Zhuang, Zi-Hui; Wen, Meng-Hsuan; Chang, Wei-Jen; Briz, Carlos G; Nieto, Marta; Shyu, Bai Chuang; Chou, Shen-Ju

    2017-01-24

    Cortical neurons must be specified and make the correct connections during development. Here, we examine a mechanism initiating neuronal circuit formation in the barrel cortex, a circuit comprising thalamocortical axons (TCAs) and layer 4 (L4) neurons. When Lhx2 is selectively deleted in postmitotic cortical neurons using conditional knockout (cKO) mice, L4 neurons in the barrel cortex are initially specified but fail to form cellular barrels or develop polarized dendrites. In Lhx2 cKO mice, TCAs from the thalamic ventral posterior nucleus reach the barrel cortex but fail to further arborize to form barrels. Several activity-regulated genes and genes involved in regulating barrel formation are downregulated in the Lhx2 cKO somatosensory cortex. Among them, Btbd3, an activity-regulated gene controlling dendritic development, is a direct downstream target of Lhx2. We find that Lhx2 confers neuronal competency for activity-dependent dendritic development in L4 neurons by inducing the expression of Btbd3. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  2. High performance railgun barrels for laboratory use

    NASA Astrophysics Data System (ADS)

    Bauer, David P.; Newman, Duane C.

    1993-01-01

    High performance low-cost, laboratory railgun barrels are now available, comprised of an inherently stiff containment structure which surrounds the bore components machined from 'off the-shelf' materials. The shape of the containment structure was selected to make the barrel inherently stiff. The structure consists of stainless steel laminations which do not compromise the electrical efficiency of the railgun. The modular design enhances the utility of the barrel, as it is easy to service between shots, and can be 're-cored' to produce different configurations and sizes using the same structure. We have produced barrels ranging from 15 mm to 90 mm square bore, a 30 mm round bore, and in lengths varying from 0.25 meters to 10 meters long. Successful tests with both plasma and solid metal armatures have demonstrated the versatility and performance of this design.

  3. An outbreak of norovirus-associated acute gastroenteritis associated with contaminated barrelled water in many schools in Zhejiang, China

    PubMed Central

    Sheng, Minyang; Song, Jianqiang; He, Fan; Qiu, Yinwei; Wu, Haocheng; Lu, Qinbao; Feng, Yan; Lin, Junfen; Chen, Enfu; Chai, Chengliang

    2017-01-01

    Objectives More than 900 students and teachers at many schools in Jiaxing city developed acute gastroenteritis in February 2014. An immediate epidemiological investigation was conducted to identify the pathogen, infection sources and route of transmission. Methods The probable cases and confirmed cases were defined as students or teachers with diarrhoea or vomiting present since the term began in February 2014. An active search was conducted for undiagnosed cases among students and teachers. Details such as demographic characteristics, gastrointestinal symptoms, and drinking water preference and frequency were collected via a uniform epidemiological questionnaire. A case-control study was implemented, and odds ratios (ORs) and 95% confidence intervals were calculated. Rectal swabs from several patients, food handlers and barrelled water factory workers, as well as water and food samples, were collected to test for potential bacteria and viruses. Results A total of 924 cases fit the definition of the probable case, including 8 cases of laboratory-confirmed norovirus infection at 13 schools in Jiaxing city between February 12 and February 21, 2014. The case-control study demonstrated that barrelled water was a risk factor (OR: 20.15, 95% CI: 2.59–156.76) and that bottled water and boiled barrelled water were protective factors (OR: 0.31, 95% CI: 0.13–0.70, and OR: 0.36, 95% CI: 0.16–0.77). A total of 11 rectal samples and 8 barrelled water samples were detected as norovirus-positive, and the genotypes of viral strains were the same (GII). The norovirus that contaminated the barrelled water largely came from the asymptomatic workers. Conclusions This acute gastroenteritis outbreak was caused by barrelled water contaminated by norovirus. The outbreak was controlled after stopping the supply of barrelled water. The barrelled water supply in China represents a potential source of acute gastroenteritis outbreaks due to the lack of surveillance and supervision. Therefore, more attention should be paid to this area. PMID:28170414

  4. An outbreak of norovirus-associated acute gastroenteritis associated with contaminated barrelled water in many schools in Zhejiang, China.

    PubMed

    Shang, Xiaopeng; Fu, Xiaofei; Zhang, Peng; Sheng, Minyang; Song, Jianqiang; He, Fan; Qiu, Yinwei; Wu, Haocheng; Lu, Qinbao; Feng, Yan; Lin, Junfen; Chen, Enfu; Chai, Chengliang

    2017-01-01

    More than 900 students and teachers at many schools in Jiaxing city developed acute gastroenteritis in February 2014. An immediate epidemiological investigation was conducted to identify the pathogen, infection sources and route of transmission. The probable cases and confirmed cases were defined as students or teachers with diarrhoea or vomiting present since the term began in February 2014. An active search was conducted for undiagnosed cases among students and teachers. Details such as demographic characteristics, gastrointestinal symptoms, and drinking water preference and frequency were collected via a uniform epidemiological questionnaire. A case-control study was implemented, and odds ratios (ORs) and 95% confidence intervals were calculated. Rectal swabs from several patients, food handlers and barrelled water factory workers, as well as water and food samples, were collected to test for potential bacteria and viruses. A total of 924 cases fit the definition of the probable case, including 8 cases of laboratory-confirmed norovirus infection at 13 schools in Jiaxing city between February 12 and February 21, 2014. The case-control study demonstrated that barrelled water was a risk factor (OR: 20.15, 95% CI: 2.59-156.76) and that bottled water and boiled barrelled water were protective factors (OR: 0.31, 95% CI: 0.13-0.70, and OR: 0.36, 95% CI: 0.16-0.77). A total of 11 rectal samples and 8 barrelled water samples were detected as norovirus-positive, and the genotypes of viral strains were the same (GII). The norovirus that contaminated the barrelled water largely came from the asymptomatic workers. This acute gastroenteritis outbreak was caused by barrelled water contaminated by norovirus. The outbreak was controlled after stopping the supply of barrelled water. The barrelled water supply in China represents a potential source of acute gastroenteritis outbreaks due to the lack of surveillance and supervision. Therefore, more attention should be paid to this area.

  5. A petroleum discovery-rate forecast revisited-The problem of field growth

    USGS Publications Warehouse

    Drew, L.J.; Schuenemeyer, J.H.

    1992-01-01

    A forecast of the future rates of discovery of crude oil and natural gas for the 123,027-km2 Miocene/Pliocene trend in the Gulf of Mexico was made in 1980. This forecast was evaluated in 1988 by comparing two sets of data: (1) the actual versus the forecasted number of fields discovered, and (2) the actual versus the forecasted volumes of crude oil and natural gas discovered with the drilling of 1,820 wildcat wells along the trend between January 1, 1977, and December 31, 1985. The forecast specified that this level of drilling would result in the discovery of 217 fields containing 1.78 billion barrels of oil equivalent; however, 238 fields containing 3.57 billion barrels of oil equivalent were actually discovered. This underestimation is attributed to biases introduced by field growth and, to a lesser degree, the artificially low, pre-1970's price of natural gas that prevented many smaller gas fields from being brought into production at the time of their discovery; most of these fields contained less than 50 billion cubic feet of producible natural gas. ?? 1992 Oxford University Press.

  6. High-resolution 2-deoxyglucose mapping of functional cortical columns in mouse barrel cortex.

    PubMed

    McCasland, J S; Woolsey, T A

    1988-12-22

    Cortical columns associated with barrels in layer IV of the somatosensory cortex were characterized by high-resolution 2-deoxy-D-glucose (2DG) autoradiography in freely behaving mice. The method demonstrates a more exact match between columnar labeling and cytoarchitectonic barrel boundaries than previously reported. The pattern of cortical activation seen with stimulation of a single whisker (third whisker in the middle row of large hairs--C3) was compared with the patterns from two control conditions--normal animals with all whiskers present ("positive control")--and with all large whiskers clipped ("negative control"). Two types of measurements were made from 2DG autoradiograms of tangential cortical sections: 1) labeled cells were identified by eye and tabulated with a computer, and 2) grain densities were obtained automatically with a computer-controlled microscope and image processor. We studied the fine-grained patterns of 2DG labeling in a nine-barrel grid with the C3 barrel in the center. From the analysis we draw five major conclusions. 1. Approximately 30-40% of the total number of neurons in the C3 barrel column are activated when only the C3 whisker is stimulated. This is about twice the number of neurons labeled in the C3 column when all whiskers are stimulated and about ten times the number of neurons labeled when all large whiskers are clipped. 2. There is evidence for a vertical functional organization within a barrel-related whisker column which has smaller dimensions in the tangential direction than a barrel. There are densely labeled patches within a barrel which are unique to an individual cortex. The same patchy pattern is found in the appropriate regions of sections above and below the barrels through the full thickness of the cortex. This functional arrangement could be considered to be a "minicolumn" or more likely a group of "minicolumns" (Mountcastle: In G.M. Edelman and U.B. Mountcastle (eds): The Material Brain: Cortical Organization and the Group-Selective Theory of Higher Brain Function. Cambridge: MIT Press, '78). 3. Within the stereotyped geometry of the barrel field, there is considerable individual variation in the radial labeling distribution in corresponding (homotypical) columns of different cerebral hemispheres. This result is consistent with the hypothesis that dynamic processes operate to determine the connection strengths between neural elements in somatosensory cortex. It provides a basis for testing various "connectionist" and "group selection" theories of neural organization and development.(ABSTRACT TRUNCATED AT 400 WORDS)

  7. Extent and mechanism of phase separation during the extrusion of calcium phosphate pastes.

    PubMed

    O'Neill, Rory; McCarthy, Helen O; Cunningham, Eoin; Montufar, Edgar; Ginebra, Maria-Pau; Wilson, D Ian; Lennon, Alex; Dunne, Nicholas

    2016-02-01

    The aim of this study was to increase understanding of the mechanism and dominant drivers influencing phase separation during ram extrusion of calcium phosphate (CaP) paste for orthopaedic applications. The liquid content of extrudate was determined, and the flow of liquid and powder phases within the syringe barrel during extrusion were observed, subject to various extrusion parameters. Increasing the initial liquid-to-powder mass ratio, LPR, (0.4-0.45), plunger rate (5-20 mm/min), and tapering the barrel exit (45°-90°) significantly reduced the extent of phase separation. Phase separation values ranged from (6.22 ± 0.69 to 18.94 ± 0.69 %). However altering needle geometry had no significant effect on phase separation. From powder tracing and liquid content determination, static zones of powder and a non-uniform liquid distribution was observed within the barrel. Measurements of extrudate and paste LPR within the barrel indicated that extrudate LPR remained constant during extrusion, while LPR of paste within the barrel decreased steadily. These observations indicate the mechanism of phase separation was located within the syringe barrel. Therefore phase separation can be attributed to either; (1) the liquid being forced downstream by an increase in pore pressure as a result of powder consolidation due to the pressure exerted by the plunger or (2) the liquid being drawn from paste within the barrel, due to suction, driven by dilation of the solids matrix at the barrel exit. Differentiating between these two mechanisms is difficult; however results obtained suggest that suction is the dominant phase separation mechanism occurring during extrusion of CaP paste.

  8. Energetics of side-chain partitioning of β-signal residues in unassisted folding of a transmembrane β-barrel protein

    PubMed Central

    Iyer, Bharat Ramasubramanian; Zadafiya, Punit; Vetal, Pallavi Vijay

    2017-01-01

    The free energy of water-to-interface amino acid partitioning is a major contributing factor in membrane protein folding and stability. The interface residues at the C terminus of transmembrane β-barrels form the β-signal motif required for assisted β-barrel assembly in vivo but are believed to be less important for β-barrel assembly in vitro. Here, we experimentally measured the thermodynamic contribution of all 20 amino acids at the β-signal motif to the unassisted folding of the model β-barrel protein PagP. We obtained the partitioning free energy for all 20 amino acids at the lipid-facing interface (ΔΔG0w,i(φ)) and the protein-facing interface (ΔΔG0w,i(π)) residues and found that hydrophobic amino acids are most favorably transferred to the lipid-facing interface, whereas charged and polar groups display the highest partitioning energy. Furthermore, the change in non-polar surface area correlated directly with the partitioning free energy for the lipid-facing residue and inversely with the protein-facing residue. We also demonstrate that the interface residues of the β-signal motif are vital for in vitro barrel assembly, because they exhibit a side chain–specific energetic contribution determined by the change in nonpolar accessible surface. We further establish that folding cooperativity and hydrophobic collapse are balanced at the membrane interface for optimal stability of the PagP β-barrel scaffold. We conclude that the PagP C-terminal β-signal motif influences the folding cooperativity and stability of the folded β-barrel and that the thermodynamic contributions of the lipid- and protein-facing residues in the transmembrane protein β-signal motif depend on the nature of the amino acid side chain. PMID:28592485

  9. Influence of aging conditions on the quality of red Sangiovese wine.

    PubMed

    Castellari, M; Piermattei, B; Arfelli, G; Amati, A

    2001-08-01

    A red Sangiovese wine was stored in barrels of different woods (oak and chestnut) and types (225-L "barriques" and 1000-L barrels) at 12 and 22 degrees C for 320 days to evaluate the effects of different aging conditions on wine quality. Chestnut barrels led to wines richer in phenolics, and which were more tannic, colored, and fruity. Oak barrels gave wines with more monomeric phenolics, but less astringent, with higher vanilla smell, and more harmonious. The type of barrel could be used as a parameter to regulate the extraction of wood components and the polymerization of monomeric phenolics. Storage at 22 degrees C favored the formation of polymerized phenolics and the increase of color density and color hue. The temperature produced less pronounced effects on aroma and taste, even if wines stored at 12 degrees C showed more harmony.

  10. Nuclear reactor alignment plate configuration

    DOEpatents

    Altman, David A; Forsyth, David R; Smith, Richard E; Singleton, Norman R

    2014-01-28

    An alignment plate that is attached to a core barrel of a pressurized water reactor and fits within slots within a top plate of a lower core shroud and upper core plate to maintain lateral alignment of the reactor internals. The alignment plate is connected to the core barrel through two vertically-spaced dowel pins that extend from the outside surface of the core barrel through a reinforcement pad and into corresponding holes in the alignment plate. Additionally, threaded fasteners are inserted around the perimeter of the reinforcement pad and into the alignment plate to further secure the alignment plate to the core barrel. A fillet weld also is deposited around the perimeter of the reinforcement pad. To accomodate thermal growth between the alignment plate and the core barrel, a gap is left above, below and at both sides of one of the dowel pins in the alignment plate holes through with the dowel pins pass.

  11. EXTERNAL BARREL TEMPERATURE OF A SMALL BORE OLYMPIC RIFLE AND SHOOTING PRECISION

    PubMed Central

    Gladyszewska, B.; Baranowski, P.; Mazurek, W.; Wozniak, J.

    2013-01-01

    Investigations on changes in a rifle's barrel temperature during shooting in a rhythm typical for practitioners of Olympic shooting sports are presented. Walther KK300 (cal. 5.6 mm), a typical rifle often used in Olympic competitions, R50 RWS ammunition and a high speed thermographic camera were used in the study. Altair version 5 software was used to process thermal images and a stationary wavelet transform was applied to denoise signals for all the studied points. It was found that the temperature of the rifle barrel does not exceed 0.3°C after one shot whereas the total temperature increase does not exceed 5°C after taking 40 shots and does not affect the position of the hitting point on a target. In fact, contrary to popular belief, the so-called “warming shots” are not done for barrel heating but for cleaning of remnants in the barrel. PMID:24744465

  12. Assessment of undiscovered oil and gas resources of the Dnieper-Donets Basin Province and Pripyat Basin Province, Russia, Ukraine, and Belarus, 2010

    USGS Publications Warehouse

    Klett, T.R.

    2011-01-01

    The U.S. Geological Survey, using a geology-based assessment methodology, estimated mean volumes of technically recoverable, conventional, undiscovered petroleum resources at 84 million barrels of crude oil, 4.7 trillion cubic feet of natural gas, and 130 million barrels of natural gas liquids for the Dnieper-Donets Basin Province and 39 million barrels of crude oil, 48 billion cubic feet of natural gas, and 1 million barrels of natural gas liquids for the Pripyat Basin Province. The assessments are part of a program to estimate these resources for priority basins throughout the world.

  13. Computer vision barrel inspection

    NASA Astrophysics Data System (ADS)

    Wolfe, William J.; Gunderson, James; Walworth, Matthew E.

    1994-02-01

    One of the Department of Energy's (DOE) ongoing tasks is the storage and inspection of a large number of waste barrels containing a variety of hazardous substances. Martin Marietta is currently contracted to develop a robotic system -- the Intelligent Mobile Sensor System (IMSS) -- for the automatic monitoring and inspection of these barrels. The IMSS is a mobile robot with multiple sensors: video cameras, illuminators, laser ranging and barcode reader. We assisted Martin Marietta in this task, specifically in the development of image processing algorithms that recognize and classify the barrel labels. Our subsystem uses video images to detect and locate the barcode, so that the barcode reader can be pointed at the barcode.

  14. Experimental evidence that stripes do not cool zebras.

    PubMed

    Horváth, Gábor; Pereszlényi, Ádám; Száz, Dénes; Barta, András; Jánosi, Imre M; Gerics, Balázs; Åkesson, Susanne

    2018-06-19

    There are as many as 18 theories for the possible functions of the stripes of zebras, one of which is to cool the animal. We performed field experiments and thermographic measurements to investigate whether thermoregulation might work for zebra-striped bodies. A zebra body was modelled by water-filled metal barrels covered with horse, cattle and zebra hides and with various black, white, grey and striped patterns. The barrels were installed in the open air for four months while their core temperature was measured continuously. Using thermography, the temperature distributions of the barrel surfaces were compared to those of living zebras. The sunlit zebra-striped barrels reproduced well the surface temperature characteristics of sunlit zebras. We found that there were no significant core temperature differences between the striped and grey barrels, even on many hot days, independent of the air temperature and wind speed. The average core temperature of the barrels increased as follows: white cattle, grey cattle, real zebra, artificial zebra, grey horse, black cattle. Consequently, we demonstrate that zebra-striped coats do not keep the body cooler than grey coats challenging the hypothesis of a thermoregulatory role of zebra stripes.

  15. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer. Each...

  16. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer. Each...

  17. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer. Each...

  18. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer. Each...

  19. Design and development of a work robot to place ATLAS SCT modules onto barrel cylinders

    NASA Astrophysics Data System (ADS)

    Terada, S.; Kobayashi, H.; Sengoku, H.; Kato, Y.; Hara, K.; Honma, F.; Ikegami, Y.; Iwata, Y.; Kohriki, T.; Kondo, T.; Nakano, I.; Takashima, R.; Tanaka, R.; Ujiie, N.; Unno, Y.; Yasuda, S.

    2005-04-01

    More than 2000 silicon modules need to be placed and fastened on the ATLAS SCT barrel tracker. A semi-automatic pick-and-place work robot was designed and developed to cope with the module placement for the SCT barrel assembly. We found that this robot could place modules to a mechanical precision of better than 25 μm.

  20. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer. Each...

  1. 40 CFR Table Nn-2 to Subpart Nn of... - Default Values for Calculation Methodology 2 of This Subpart

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Natural Gas and Natural Gas Liquids Pt. 98, Subpt. NN, Table NN-2 Table NN-2 to Subpart NN of Part 98.../Unit) 1 Natural Gas Mscf 0.0544 Propane Barrel 0.241 Normal butane Barrel 0.281 Ethane Barrel 0.170...

  2. Assessment of undiscovered oil and gas resources of the Amu Darya Basin and Afghan-Tajik Basin Provinces, Afghanistan, Iran, Tajikistan, Turkmenistan, and Uzbekistan, 2011

    USGS Publications Warehouse

    Klett, T.R.; Schenk, Christopher J.; Wandrey, Craig J.; Charpentier, Ronald R.; Brownfield, Michael E.; Pitman, Janet K.; Pollastro, Richard M.; Cook, Troy A.; Tennyson, Marilyn E.

    2012-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated volumes of undiscovered, technically recoverable, conventional petroleum resources for the Amu Darya Basin and Afghan–Tajik Basin Provinces of Afghanistan, Iran, Tajikistan, Turkmenistan, and Uzbekistan. The mean volumes were estimated at 962 million barrels of crude oil, 52 trillion cubic feet of natural gas, and 582 million barrels of natural gas liquids for the Amu Darya Basin Province and at 946 million barrels of crude oil, 7 trillion cubic feet of natural gas, and 85 million barrels of natural gas liquids for the Afghan–Tajik Basin Province.

  3. Low Leachable Container System Consisting of a Polymer-Based Syringe with Chlorinated Isoprene Isobutene Rubber Plunger Stopper.

    PubMed

    Kiminami, Hideaki; Takeuchi, Katsuyuki; Nakamura, Koji; Abe, Yoshihiko; Lauwers, Philippe; Dierick, William; Yoshino, Keisuke; Suzuki, Shigeru

    2015-01-01

    A 36 month leachable study on water for injection in direct contact within a polymer-based prefillable syringe consisting of a cyclo olefin polymer barrel, a chlorinated isoprene isobutene rubber plunger stopper, a polymer label attached on the barrel, and a secondary packaging was conducted at 25 ± 2 °C and 60 ± 5% relative humidity. Through the various comparison studies, no difference in the leachable amounts was observed between this polymer-based prefilled syringe and a glass bottle as a blank sample reference by 36 months. No influence on the leachables study outcome was noted from the printed label and/or label adhesive or from the secondary packaging. In an additional study, no acrylic acid used as the label adhesive leachable was detected by an extended storage for 45 months at 25 ± 2 °C and 60 ± 5% relative humidity as a worst case. To obtain more details, a comparison extractable study was conducted between a cyclo olefin polymer barrel and a glass barrel. In addition, chlorinated isoprene isobutene rubber and bromo isoprene isobutene rubber were compared. As a result, no remarkable difference was found in the organic extractables for syringe barrels. On the other hand, in the case of element extractable analysis, the values for the cyclo olefin polymer barrel were lower than that for the glass barrel. For the plunger stoppers, the chlorinated isoprene isobutene rubber applied in this study was showing a lower extractable profile as compared to the bromo isoprene isobutene rubber, both for organic and element extractables. In conclusion, the proposed polymer-based prefillable syringe system has great potential and represents a novel alternative that can achieve very low level extractable profiles and can bring additional value to the highly sensitive biotech drug market. A 36 month leachable study on water for injection in direct contact within a cyclo olefin polymer barrel and chlorinated isoprene isobutene rubber plunger stopper that has a polymer label attached to the barrel and is wrapped into a secondary packaging was conducted at 25 °C and 60% relative humidity. Through the various comparison studies, no difference in the leachable amounts was observed between polymer-based prefilled syringes and a glass bottle as a blank sample reference by 36 months. No influences on the leachables study outcome were noted from the secondary packaging. To obtain more details, a comparison extractable study was conducted between the cyclo olefin polymer and the glass barrel. In addition, chlorinated isoprene isobutene rubber and bromo isoprene isobutene rubber plunger stoppers were compared as well. As a result, no remarkable difference was found in the organic extractables for barrels. As for element extractable analysis, the values for the cyclo olefin polymer barrel were lower than that for the glass barrel. For the plunger stoppers, the chlorinated isoprene isobutene rubber applied in this study was showing a lower extractable profile as compared to the bromo isoprene isobutene rubber, both for organic and element extractables. In conclusion, the proposed polymer-based prefillable syringe system has great potential and represents a novel alternative that can achieve very low level extractable profiles and can bring additional value to the highly sensitive biotech drug market. © PDA, Inc. 2015.

  4. Variations in oxygen and ellagitannins, and organoleptic properties of red wine aged in French oak barrels classified by a near infrared system.

    PubMed

    Michel, Julien; Albertin, Warren; Jourdes, Michael; Le Floch, Alexandra; Giordanengo, Thomas; Mourey, Nicolas; Teissedre, Pierre-Louis

    2016-08-01

    During wine aging in barrels, antioxidant molecules from wood, such as ellagitannins, are solubilized and react with wine molecules and oxygen. However, their concentrations are highly variable. Oxygen is an important factor, as it plays a role in wine parameters and organoleptic perceptions. Five barrel modalities were used; three polyphenol indices (IP), classified using the NIRS procedure, and three grain qualities. Barrels were equipped with windows to measure the oxygen using luminescence technology. The ellagitannin concentrations in the wine and its organoleptic properties were monitored. Oxygen concentrations decreased quickly during the first 8days of aging and this phenomenon was significantly more marked in barrels with a higher IP and medium grain. The ellagitannin concentrations were believed to be correlated with wood classification and oxygen consumption. Furthermore, the organoleptic properties were significantly impacted, as the wine with the lowest ellagitannin level was described as less astringent, bitter, woody, and smoky/toasty. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Ellagitannin content, volatile composition and sensory profile of wines from different countries matured in oak barrels subjected to different toasting methods.

    PubMed

    González-Centeno, M R; Chira, K; Teissedre, P-L

    2016-11-01

    Ellagitannins and aromatic compounds evolution in Cabernet Sauvignon wines macerated in oak barrels for a year was studied. Identical barrels with different toastings (medium toasting, medium toasting with watering, Noisette) were used in French, Italian and USA cellars. Ellagitannins increased by 84-96% with aging time, as did woody volatiles, by 86-91% in French wines and 23-35% in Italian wines, while fruity aroma compounds declined by 50-57% in the French and Italian wines over a 12-months period. Nevertheless, other behaviors and different kinetics rates for these compounds were observed depending on barrel toasting, wine matrix and their interactions. Perceived overall woody intensity was closely related to trans-whiskey lactone, guaiacol and vanillin, whereas astringency and bitterness were significantly linked to ellagitannins (p<0.05). This is the first study that evaluates the toasting effect on wines from different countries matured in the same oak barrels. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Usage of FT-ICR-MS Metabolomics for Characterizing the Chemical Signatures of Barrel-Aged Whisky

    PubMed Central

    Roullier-Gall, Chloé; Signoret, Julie; Hemmler, Daniel; Witting, Michael A.; Kanawati, Basem; Schäfer, Bernhard; Gougeon, Régis D.; Schmitt-Kopplin, Philippe

    2018-01-01

    Whisky can be described as a complex matrix integrating the chemical history from the fermented cereals, the wooden barrels, the specific distillery processes, aging, and environmental factors. In this study, using Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) and liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), we analyzed 150 whisky samples from 49 different distilleries, 7 countries, and ranging from 1 day new make spirit to 43 years of maturation with different types of barrel. Chemometrics revealed the unexpected impact of the wood history on the distillate's composition during barrel aging, regardless of the whisky origin. Flavonols, oligolignols, and fatty acids are examples of important chemical signatures for Bourbon casks, whereas a high number of polyphenol glycosides, including for instance quercetin-glucuronide or myricetin-glucoside as potential candidates, and carbohydrates would discriminate Sherry casks. However, the comparison of barrel aged rums and whiskies revealed specific signatures, highlighting the importance of the initial composition of the distillate and the distillery processes. PMID:29520358

  7. Texture coarseness responsive neurons and their mapping in layer 2–3 of the rat barrel cortex in vivo

    PubMed Central

    Garion, Liora; Dubin, Uri; Rubin, Yoav; Khateb, Mohamed; Schiller, Yitzhak; Azouz, Rony; Schiller, Jackie

    2014-01-01

    Texture discrimination is a fundamental function of somatosensory systems, yet the manner by which texture is coded and spatially represented in the barrel cortex are largely unknown. Using in vivo two-photon calcium imaging in the rat barrel cortex during artificial whisking against different surface coarseness or controlled passive whisker vibrations simulating different coarseness, we show that layer 2–3 neurons within barrel boundaries differentially respond to specific texture coarsenesses, while only a minority of neurons responded monotonically with increased or decreased surface coarseness. Neurons with similar preferred texture coarseness were spatially clustered. Multi-contact single unit recordings showed a vertical columnar organization of texture coarseness preference in layer 2–3. These findings indicate that layer 2–3 neurons perform high hierarchical processing of tactile information, with surface coarseness embodied by distinct neuronal subpopulations that are spatially mapped onto the barrel cortex. DOI: http://dx.doi.org/10.7554/eLife.03405.001 PMID:25233151

  8. Usage of FT-ICR-MS Metabolomics for characterizing the chemical signatures of barrel-aged whisky

    NASA Astrophysics Data System (ADS)

    Roullier-Gall, Chloé; Signoret, Julie; Hemmler, Daniel; Witting, Michael A.; Kanawati, Basem; Schäfer, Bernhard; Gougeon, Régis D.; Schmitt-Kopplin, Philippe

    2018-02-01

    Whisky can be described as a complex matrix integrating the chemical history from the fermented cereals, the wooden barrels, the specific distillery processes, ageing and environmental factors. In this study, using Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) and liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), we analysed 150 whisky samples from 49 different distilleries, 7 countries, and ranging from 1 day new make spirit to 43 years of maturation with different types of barrel. Chemometrics revealed the unexpected impact of the wood history on the distillatés composition during barrel ageing, regardless of the whisky origin. Flavonols, oligolignols and fatty acids are examples of important chemical signatures for Bourbon casks, whereas a high number of polyphenol glycosides, including for instance quercetin-glucuronide or myricetin-glucoside as potential candidates, and carbohydrates would discriminate Sherry casks. However, the comparison of barrel aged rums and whiskies revealed specific signatures, highlighting the importance of the initial composition of the distillate and the distillery processes.

  9. Characterization of the targeting signal in mitochondrial β-barrel proteins

    PubMed Central

    Jores, Tobias; Klinger, Anna; Groß, Lucia E.; Kawano, Shin; Flinner, Nadine; Duchardt-Ferner, Elke; Wöhnert, Jens; Kalbacher, Hubert; Endo, Toshiya; Schleiff, Enrico; Rapaport, Doron

    2016-01-01

    Mitochondrial β-barrel proteins are synthesized on cytosolic ribosomes and must be specifically targeted to the organelle before their integration into the mitochondrial outer membrane. The signal that assures such precise targeting and its recognition by the organelle remained obscure. In the present study we show that a specialized β-hairpin motif is this long searched for signal. We demonstrate that a synthetic β-hairpin peptide competes with the import of mitochondrial β-barrel proteins and that proteins harbouring a β-hairpin peptide fused to passenger domains are targeted to mitochondria. Furthermore, a β-hairpin motif from mitochondrial proteins targets chloroplast β-barrel proteins to mitochondria. The mitochondrial targeting depends on the hydrophobicity of the β-hairpin motif. Finally, this motif interacts with the mitochondrial import receptor Tom20. Collectively, we reveal that β-barrel proteins are targeted to mitochondria by a dedicated β-hairpin element, and this motif is recognized at the organelle surface by the outer membrane translocase. PMID:27345737

  10. 1400392

    NASA Image and Video Library

    2014-06-05

    DAVID OSBORNE, A MACHINIST ON THE METTS CONTRACT, INSPECTS THE ORTHOGRID TOOL PATH ON AN 8 FOOT CF1 BARREL IN SUPPORT OF THE SHELL BUCKLING TEST FOR LANGLEY RESEARCH CENTER. THIS IS THE FIRST BARREL THAT MSFC HAS MANUFACTURED FROM EXTRUDED MATERIAL, VERSUS THE ORIGINAL DESIGN BEING 3 SECTIONS BARREL PANELS THAT WERE FRICTION STIR WELDED. THE TESTING WILL SHOW THE DIFFERENT STRENGTH PROPERTIES FROM A WELDED VERSION TO A FULLY EXTRUDED PIECE OF MATERIAL.

  11. Normal Modes of Vibration of the PHALANX Gun

    DTIC Science & Technology

    1993-06-01

    Clamps Bricks, Thin Shells, Rigid Elements Mid-Barrel Clamps Bricks, Rigid Elements Barrels Beams with tubular cross-section Stub Rotor Bricks, Thin...Shells Rotor Bricks Needle Bearing Bricks, Springs Casing Thin Shells Thrust Bearing Bricks, Springs Recoil Adapters Bricks, Rigid Elements, Springs... rigid elements were used to connect the barrels to the clamps and stub rotor and the recoil adapter springs to 48 the gun body. "End release codes

  12. Measuring the Blast and Ballistic Performance of Armor

    DTIC Science & Technology

    2015-10-15

    Typical ballistic test instrumentation is depicted in Fig. 1. The gun system employs a Mann barrel , available in a range of calibers1 (e.g., .22 cal...setup. (A) Mann barrel gun system; (B) computer and data acquisition interface; (C) remote, manual trigger; (D) velocity screens; (E) high speed video...1 Caliber corresponds to the diameter of the gun barrel , usually expressed in inches; e.g., .30 cal

  13. Water requirements of the petroleum refining industry

    USGS Publications Warehouse

    Otts, Louis Ethelbert

    1964-01-01

    About 3,500 million gallons of water was withdrawn daily in 1955 for use by petroleum refineries in the United States. This was about 3 percent of the estimated daily withdrawal of industrial water in the United States in 1955. An average of 468 gallons of water was required to refine a barrel of crude oil, and the median was 95 gallons of water per barrel of crude charge; withdrawals ranged from 6.5 to 3,240 gallons per barrel. Ninety-one percent of the water requirements of the petroleum refineries surveyed was for cooling. One-third of the refineries reused their cooling water from 10 to more than 50 times. Only 17 refineries used once-through cooling systems. Refineries with recirculating cooling systems circulated about twice as much cooling water but needed about 25 times less makeup; however, they consumed about 24 times more water per barrel of charge than refineries using once-through cooling systems. The average noncracking refinery used about 375 gallons of water per barrel of crude, which is less than the 471-gallon average of refineries with cracking facilities. Refineries are composed of various processing units, and the water requirements of such units varied ; median makeup needs ranged from about 125 gallons per barrel for polymerization and alkylation units to 15.5 gallons per barrel for distillation units. Refinery-owned sources of water supplied 95 percent of the makeup-water requirements. Surface-water sources provided 86 percent of the makeup-water demand. Less than 1 percent of the makeup water was obtained from reprocessed municipal sewage.

  14. Estimated Minimum Discharge Rates of the Deepwater Horizon Spill-Interim Report to the Flow Rate Technical Group from the Mass Balance Team

    USGS Publications Warehouse

    Labson, Victor F.; Clark, Roger N.; Swayze, Gregg A.; Hoefen, Todd M.; Kokaly, Raymond F.; Livo, K. Eric; Powers, Michael H.; Plumlee, Geoffrey S.; Meeker, Gregory P.

    2010-01-01

    All of the calculations and results in this report are preliminary and intended for the purpose, and only for the purpose, of aiding the incident team in assessing the extent of the spilled oil for ongoing response efforts. Other applications of this report are not authorized and are not considered valid. Because of time constraints and limitations of data available to the experts, many of their estimates are approximate, are subject to revision, and certainly should not be used as the Federal Government's final values for assessing volume of the spill or its impact to the environment or to coastal communities. Each expert that contributed to this report reserves the right to alter his conclusions based upon further analysis or additional information. An estimated minimum total oil discharge was determined by calculations of oil volumes measured as of May 17, 2010. This included oil on the ocean surface measured with satellite and airborne images and with spectroscopic data (129,000 barrels to 246,000 barrels using less and more aggressive assumptions, respectively), oil skimmed off the surface (23,500 barrels from U.S. Coast Guard [USCG] estimates), oil burned off the surface (11,500 barrels from USCG estimates), dispersed subsea oil (67,000 to 114,000 barrels), and oil evaporated or dissolved (109,000 to 185,000 barrels). Sedimentation (oil captured from Mississippi River silt and deposited on the ocean bottom), biodegradation, and other processes may indicate significant oil volumes beyond our analyses, as will any subsurface volumes such as suspended tar balls or other emulsions that are not included in our estimates. The lower bounds of total measured volumes are estimated to be within the range of 340,000 to 580,000 barrels as of May 17, 2010, for an estimated average minimum discharge rate of 12,500 to 21,500 barrels per day for 27 days from April 20 to May 17, 2010.

  15. Optimization of Performance Parameters for Large Area Silicon Photomultipliers

    NASA Astrophysics Data System (ADS)

    Janzen, Kathryn

    2008-10-01

    The goal of the GlueX experiment is to search for exotic hybrid mesons as evidence of gluonic excitations in an effort to better understand confinement. A key component of the GlueX detector is the electromagnetic barrel calorimeter (BCAL) located immediately inside a superconducting solenoid of approximately 2.5T. Because of this arrangement, traditional vacuum photomultiplier tubes (PMTs) which are affected significantly by magnetic fields cannot be used on the BCAL. The use of Silicon photomultipliers (SiPMs) as front-end detectors has been proposed. While the largest SiPMs that have been previously employed by other experiments are 1x1 mm^2, GlueX proposes to use large area SiPMs each composed of 16 - 3x3 mm^2 cells in a 4x4 array. This puts the GlueX collaboration in the unique position of driving the technology for larger area sensors. In this talk I will discuss tests done in Regina regarding performance parameters of prototype SiPM arrays delivered by SensL, a photonics research and development company based in Ireland, as well as sample 1x1 mm^2 and 3x3 mm^2 SiPMs.

  16. Geographic Concentration of Oil Infrastructure: Issues and Options

    DTIC Science & Technology

    2007-03-24

    their homes and plants , and destroy ports and refineries , thereby shattering the U.S. economy. The scope, scale, frequency and location of terrorist...for the above reasons. The corridor along the Mississippi River between Baton Rouge and New Orleans is home to six major refineries . These... refineries process more than 1.7 million barrels of oil per day to produce 775 thousand barrels of motor gasoline and 440 million barrels of distillate fuel

  17. Analysis of Pacific Fleet Underway Replenishment Data

    DTIC Science & Technology

    1988-09-01

    described in Chapter 12 of NWP-I IE predicts requirements to support the operating forces. Ad- equate material (POL Ammunition Stores) must be available to...Mr. John Hammet at NSWSES, Port Hueneme, CA. 5 moving material between ships is established, however the procedures to control the material moved is...represent faster transfers. As an example 15 minutes per thousand barrels equates to 4000 barrels per hour while 20 minutes per thousand barrels equates

  18. 2011 International Infantry and Joint Services Small Arms Systems Symposium, Exhibition and Firing Demonstration

    DTIC Science & Technology

    2011-05-26

    Machine Gun 24 12.7mm NATO Nominated Weapon United States – General Dynamics M2 Heavy Barrel Machine Gun 25...Explosively-Clad Refractory Barrel Liners for Small Caliber Machine Guns , Dr. Douglas Taylor, TPL, Inc. 12299 - The HAMR Project, Mr. Xavier Gavage, FN Herstal... Barrel Liners for Small Caliber Machine Guns Dr. Douglas Taylor, TPL, Inc. 12330 - 40mm Low Velocity Air-Burst Munitions System Mr.

  19. Measuring Stability and Security in Iraq

    DTIC Science & Technology

    2009-03-01

    faces a budget deficit of $20 billion in 2009 based on a price of $50 per barrel and an export rate of 2.0 million barrels per day. Current oil prices...security details with handguns and assist them in obtaining MoI weapons cards. In addition to protection officers, the Coalition assists with...production throughout 2009. Overall, crude oil production peaked at 2.54 million barrels per day (mbpd) in July 2008 and leveled off at approximately

  20. SCB initiator

    DOEpatents

    Bickes Jr., Robert W.; Renlund, Anita M.; Stanton, Philip L.

    1994-11-01

    A detonator for high explosives initiated by mechanical impact includes a cylindrical barrel, a layer of flyer material mechanically covering the barrel at one end, and a semiconductor bridge ignitor including a pair of electrically conductive pads connected by a semiconductor bridge. The bridge is in operational contact with the layer, whereby ignition of said bridge forces a portion of the layer through the barrel to detonate the explosive. Input means are provided for igniting the semiconductor bridge ignitor.

  1. SCB initiator

    DOEpatents

    Bickes, Jr., Robert W.; Renlund, Anita M.; Stanton, Philip L.

    1994-01-01

    A detonator for high explosives initiated by mechanical impact includes a cylindrical barrel, a layer of flyer material mechanically covering the barrel at one end, and a semiconductor bridge ignitor including a pair of electrically conductive pads connected by a semiconductor bridge. The bridge is in operational contact with the layer, whereby ignition of said bridge forces a portion of the layer through the barrel to detonate the explosive. Input means are provided for igniting the semiconductor bridge ignitor.

  2. Evaluation of brine disposal from the Bryan Mound site of the strategic petroleum reserve program. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Case, Robert J.; Chittenden, Jr, Mark E.; Harper, Jr, Donald E.

    1981-01-01

    On March 10, 1980, the Department of Energy's Strategic Petroleum Reserve Program began leaching the Bryan Mound salt dome and discharging the resulting brine into the coastal waters off Freeport, Texas. During the months of March and April, a team of scientists and engineers from Texas A and M University conducted an intensive environmental study of the area surrounding the diffuser site. A pipeline has been laid from the Bryan Mound site to a location 12.5 statute miles (20 km) offshore. The last 3060 ft (933 m) of this pipeline is a 52-port diffuser through which brine can be dischargedmore » at a maximum rate of 680,000 barrels per day. Initially, 16 ports were open which permitted a maximum discharge rate of 350,000 barrels per day and a continuous brine discharge was achieved on March 13, 1980. The purpose of this report is to describe the findings of the project team during the intensive postdisposal study period of March and April, 1980. The major areas of investigation are physical oceanography, analysis of the discharge plume, water and sediment quality, nekton, benthos, phytoplankton, zooplankton, and data management.« less

  3. Israeli co-retorting of coal and oil shale would break even at 22/barrel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Work is being carried out at the Hebrew University of Jerusalem on co-retorting of coal and oil shale. The work is funded under a cooperative agreement with the US Department of Energy. The project is exploring the conversion of US eastern high-sulfur bituminous coal in a split-stage, fluidized-bed reactor. Pyrolysis occurs in the first stage and char combustion in the second stage. These data for coal will be compared with similar data from the same reactor fueled by high-sulfur eastern US oil shale and Israeli oil shales. The project includes research at three major levels: pyrolysis in lab-scale fluidized-bed reactor;more » retorting in split-stage, fluidized-bed bench-scale process (1/4 tpd); and scale-up, preparation of full-size flowchart, and economic evaluation. In the past year's research, a preliminary economic evaluation was completed for a scaled-up process using a feed of high-sulfur coal and carbonate-containing Israeli oil shale. A full-scale plant in Israel was estimated to break even at an equivalent crude oil price of $150/ton ($22/barrel).« less

  4. R&D progress in SRF surface preparation with centrifugal barrel polishing (cbp) for both Nb and Cu

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Palczewski, Ari

    Centrifugal Barrel polishing (CBP) is becoming a common R&D tool for SRF cavity preparation around the world. During the CBP process a cylindrically symmetric SRF cavity is filled with relatively cheap and environmentally friendly abrasive and sealed. The cavity is then spun around a cylindrically symmetric axis at high speeds uniformly conditioning the inner surface. This uniformity is especially relevant for SRF application because many times a single manufacturing defects limits cavity?s performance well below it?s theoretical limit. In addition CBP has created surfaces with roughness?s on the order of 10?s of nm which create a unique surface for wetmore » chemistry or thin film deposition. CBP is now being utilized at Jefferson Laboratory, Fermi Laboratory and Cornell University in the US, Deutsches Elektronen-Synchrotron in Germany, Laboratori Nazionali di Legnaro in Italy, and Raja Ramanna Centre for Advanced Technology in India. In this talk we will present current CBP research from each lab including equipment, baseline recipes, cavity removal rates and subsequent cryogenic cavity tests on niobium as well as copper cavities where available.« less

  5. The Effects of CO2 Injection and Barrel Temperatures on the Physiochemical and Antioxidant Properties of Extruded Cereals

    PubMed Central

    Thin, Thazin; Myat, Lin; Ryu, Gi-Hyung

    2016-01-01

    The effects of CO2 injection and barrel temperatures on the physiochemical and antioxidant properties of extruded cereals (sorghum, barley, oats, and millet) were studied. Extrusion was carried out using a twin-screw extruder at different barrel temperatures (80, 110, and 140°C), CO2 injection (0 and 500 mL/min), screw speed of 200 rpm, and moisture content of 25%. Extrusion significantly increased the total flavonoid content (TFC) of extruded oats, and β-glucan and protein digestibility (PD) of extruded barley and oats. In contrast, there were significant reductions in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, PD of extruded sorghum and millet, as well as resistant starch (RS) of extruded sorghum and barley, and total phenolic content (TPC) of all extrudates, except extruded millet. At a barrel temperature of 140°C, TPC in extruded barley was significantly increased, and there was also an increase in DPPH and PD in extruded millet with or without CO2 injection. In contrast, at a barrel temperature of 140°C, the TPC of extruded sorghum decreased, TFC of extruded oats decreased, and at a barrel temperature of 110°C, PD of extruded sorghum without CO2 decreased. Some physical properties [expansion ratio (ER), specific length, piece density, color, and water absorption index] of the extrudates were significantly affected by the increase in barrel temperature. The CO2 injection significantly affected some physical properties (ER, specific length, piece density, water solubility index, and water absorption index), TPC, DPPH, β-glucan, and PD. In conclusion, extruded barley and millet had higher potential for making value added cereal-based foods than the other cereals. PMID:27752504

  6. Investigation of Innovative Lightcraft Designs for Hypersonic Air Breathing and Rocket Flight by Beamed Energy Propulsion

    DTIC Science & Technology

    2012-06-01

    driven down the barrel , compressing the test gas in an approximately isentropic manner. A representative pressure history measured within in the barrel ...have shown that the isentropic compression is a good approximation for the test flow which is first discharged from the barrel . A survey of nozzle exit...of the craft, and air is delivered by an axi-symmetric, internal compression inlet. The external laser induced df’tnnation configuration

  7. Temporal Progression of Visual Injury from Blast Exposure

    DTIC Science & Technology

    2013-09-01

    included the design and construction of a silencer and dump tank. The final design is shown in Figure 8. A steel barrel lined with 2” of acoustic foam...was selected as the dump tank. It surrounds a rubber barrel lined with foam composite. The steel barrel is allowed to recoil on a cart, absorbing...test. Figure 8. (Left) Inner silencer assembly completed during Q4 of Year 1. (Right) Final silencer assembly with the outer steel drum

  8. Stealing the Sword: Limiting Terrorist Use of Advanced Conventional Weapons

    DTIC Science & Technology

    2007-01-01

    ammunition, are combined (see Figure 2.9 for a handgun concept that features four barrels , two with lethal and two with nonlethal ammunition). Other...Weapons Figure 2.9 A Four- Barreled Concept Handgun Mortar Systems Mortars have long been regarded as cheap, lightweight, short-range artillery. Mortars are...Terrorists? 37 manner).63 An example of an advance in lightweight materials for mor- tars is the development of the carbon fiber composite barrel in the

  9. Combining image processing and modeling to generate traces of beta-strands from cryo-EM density images of beta-barrels.

    PubMed

    Si, Dong; He, Jing

    2014-01-01

    Electron cryo-microscopy (Cryo-EM) technique produces 3-dimensional (3D) density images of proteins. When resolution of the images is not high enough to resolve the molecular details, it is challenging for image processing methods to enhance the molecular features. β-barrel is a particular structure feature that is formed by multiple β-strands in a barrel shape. There is no existing method to derive β-strands from the 3D image of a β-barrel at medium resolutions. We propose a new method, StrandRoller, to generate a small set of possible β-traces from the density images at medium resolutions of 5-10Å. StrandRoller has been tested using eleven β-barrel images simulated to 10Å resolution and one image isolated from the experimentally derived cryo-EM density image at 6.7Å resolution. StrandRoller was able to detect 81.84% of the β-strands with an overall 1.5Å 2-way distance between the detected and the observed β-traces, if the best of fifteen detections is considered. Our results suggest that it is possible to derive a small set of possible β-traces from the β-barrel cryo-EM image at medium resolutions even when no separation of the β-strands is visible in the images.

  10. Estimates of in-place oil shale of various grades in federal lands, Piceance Basin, Colorado

    USGS Publications Warehouse

    Mercier, Tracey J.; Johnson, Ronald C.; Brownfield, Michael E.

    2010-01-01

    The entire oil shale interval in the Piceance Basin is subdivided into seventeen “rich” and “lean” zones that were assessed separately. These zones are roughly time-stratigraphic units consisting of distinctive, laterally continuous sequences of oil shale beds that can be traced throughout much of the Piceance Basin. Several subtotals of the 1.5 trillion barrels total were calculated: (1) about 920 billion barrels (60 percent) exceed 15 gallons per ton (GPT); (2) about 352 billion barrels (23 percent) exceed 25 GPT; (3) more than one trillion barrels (70 percent) underlie Federally-managed lands; and (4) about 689 billion barrels (75 percent) of the 15 GPT total and about 284 billion barrels (19 percent) of the 25 GPT total are under Federal mineral (subsurface) ownership. These 15 and 25 GPT estimates include only those areas where the weighted average of an entire zone exceeds those minimum cutoffs. In areas where the entire zone does not meet the minimum criteria, some oil shale intervals of significant thicknesses could exist within the zone that exceed these minimum cutoffs. For example, a 30-ft interval within an oil shale zone might exceed 25 GPT but if the entire zone averages less than 25 GPT, these resources are not included in the 15 and 25 GPT subtotals, although they might be exploited in the future.

  11. Characterization of Membrane Patch-Ion Channel Probes for Scanning Ion Conductance Microscopy.

    PubMed

    Shi, Wenqing; Zeng, Yuhan; Zhu, Cheng; Xiao, Yucheng; Cummins, Theodore R; Hou, Jianghui; Baker, Lane A

    2018-05-01

    Integration of dual-barrel membrane patch-ion channel probes (MP-ICPs) to scanning ion conductance microscopy (SICM) holds promise of providing a revolutionized approach of spatially resolved chemical sensing. A series of experiments are performed to further the understanding of the system and to answer some fundamental questions, in preparation for future developments of this approach. First, MP-ICPs are constructed that contain different types of ion channels including transient receptor potential vanilloid 1 and large conductance Ca2 + -activated K + channels to establish the generalizability of the methods. Next, the capability of the MP-ICP platforms in single ion channel activity measurements is proved. In addition, the interplay between the SICM barrel and the ICP barrel is studied. For ion channels gated by uncharged ligands, channel activity at the ICP barrel is unaffected by the SICM barrel potential; whereas for ion channels that are gated by charged ligands, enhanced channel activity can be obtained by biasing the SICM barrel at potentials with opposite polarity to the charge of the ligand molecules. Finally, a proof-of-principle experiment is performed and site-specific molecular/ionic flux sensing is demonstrated at single-ion-channel level, which show that the MP-ICP platform can be used to quantify local molecular/ionic concentrations. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Similarity of different beta-strands flanked in loops by glycines and prolines from distinct (alpha/beta)8-barrel enzymes: chance or a homology?

    PubMed Central

    Janecek, S.

    1995-01-01

    Many (alpha/beta)8-barrel enzymes contain their conserved sequence regions at or around the beta-strand segments that are often preceded and succeeded by glycines and prolines, respectively. alpha-Amylase is one of these enzymes. Its sequences exhibit a very low degree of similarity, but strong conservation is seen around its beta-strands. These conserved regions were used in the search for similarities with beta-strands of other (alpha/beta)8-barrel enzymes. The analysis revealed an interesting similarity between the segment around the beta 2-strand of alpha-amylase and the one around the beta 4-strand of glycolate oxidase that are flanked in loops by glycines and prolines. The similarity can be further extended on other members of the alpha-amylase and glycolate oxidase subfamilies, i.e., cyclodextrin glycosyltransferase and oligo-1,6-glucosidase, and flavocytochrome b2, respectively. Moreover, the alpha-subunit of tryptophan synthase, the (alpha/beta)8-barrel enzyme belonging to the other subfamily of (alpha/beta)8-barrels, has both investigated strands, beta 2 and beta 4, similar to beta 2 of alpha-amylase and beta 4 of glycolate oxidase. The possibilities of whether this similarity exists only by chance or is a consequence of some processes during the evolution of (alpha/beta)8-barrel proteins are briefly discussed. PMID:7549888

  13. Similarity of different beta-strands flanked in loops by glycines and prolines from distinct (alpha/beta)8-barrel enzymes: chance or a homology?

    PubMed

    Janecek, S

    1995-06-01

    Many (alpha/beta)8-barrel enzymes contain their conserved sequence regions at or around the beta-strand segments that are often preceded and succeeded by glycines and prolines, respectively. alpha-Amylase is one of these enzymes. Its sequences exhibit a very low degree of similarity, but strong conservation is seen around its beta-strands. These conserved regions were used in the search for similarities with beta-strands of other (alpha/beta)8-barrel enzymes. The analysis revealed an interesting similarity between the segment around the beta 2-strand of alpha-amylase and the one around the beta 4-strand of glycolate oxidase that are flanked in loops by glycines and prolines. The similarity can be further extended on other members of the alpha-amylase and glycolate oxidase subfamilies, i.e., cyclodextrin glycosyltransferase and oligo-1,6-glucosidase, and flavocytochrome b2, respectively. Moreover, the alpha-subunit of tryptophan synthase, the (alpha/beta)8-barrel enzyme belonging to the other subfamily of (alpha/beta)8-barrels, has both investigated strands, beta 2 and beta 4, similar to beta 2 of alpha-amylase and beta 4 of glycolate oxidase. The possibilities of whether this similarity exists only by chance or is a consequence of some processes during the evolution of (alpha/beta)8-barrel proteins are briefly discussed.

  14. Fire testing and infrared thermography of oak barrels filled with distilled spirits (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    de Vries, Jaap

    2017-05-01

    Adequate fire protection of distilled spirits stored in oak barrels requires understanding the failure mode of these barrels, including quantifying the leak rate. In this study, the use of a custom-calibrated, long-wave microbolometer camera is demonstrated to seek new protection methods for rack-stored distilled spirits. Individual oak barrels ranging between 200 L and 500 L filled with 75%/25% ethanol/water were exposed to both propane gas fires and pure ethanol pool fires. The IR camera was used to see through the smoke and flames showing the location of the leaks. The increase in HRR due to the leaked content was measured using gas calorimetry of the combustion products. This study showed that barrels leaked at a rate of approximately 4-8 lpm, resulting in heat release rates ranging between 1.2 and 2.4 MW. These numbers are confirmed by the quantitative measurements of gaseous H2O and CO¬2 in the exhaust. Surface temperature of the exposed oak could reach temperatures up to 750ºC.

  15. Tob38, a novel essential component in the biogenesis of β-barrel proteins of mitochondria

    PubMed Central

    Waizenegger, Thomas; Habib, Shukry J; Lech, Maciej; Mokranjac, Dejana; Paschen, Stefan A; Hell, Kai; Neupert, Walter; Rapaport, Doron

    2004-01-01

    Insertion of β-barrel proteins into the outer membrane of mitochondria is mediated by the TOB complex. Known constituents of this complex are Tob55 and Mas37. We identified a novel component, Tob38. It is essential for viability of yeast and the function of the TOB complex. Tob38 is exposed on the surface of the mitochondrial outer membrane. It interacts with Mas37 and Tob55 and is associated with Tob55 even in the absence of Mas37. The Tob38–Tob55 core complex binds precursors of β-barrel proteins and facilitates their insertion into the outer membrane. Depletion of Tob38 results in strongly reduced levels of Tob55 and Mas37 and the residual proteins no longer form a complex. Tob38-depleted mitochondria are deficient in the import of β-barrel precursor proteins, but not of other outer membrane proteins or proteins of other mitochondrial subcompartments. We conclude that Tob38 has a crucial function in the biogenesis of β-barrel proteins of mitochondria. PMID:15205677

  16. Late emergence of the vibrissa direction selectivity map in the rat barrel cortex.

    PubMed

    Kremer, Yves; Léger, Jean-François; Goodman, Dan; Brette, Romain; Bourdieu, Laurent

    2011-07-20

    In the neocortex, neuronal selectivities for multiple sensorimotor modalities are often distributed in topographical maps thought to emerge during a restricted period in early postnatal development. Rodent barrel cortex contains a somatotopic map for vibrissa identity, but the existence of maps representing other tactile features has not been clearly demonstrated. We addressed the issue of the existence in the rat cortex of an intrabarrel map for vibrissa movement direction using in vivo two-photon imaging. We discovered that the emergence of a direction map in rat barrel cortex occurs long after all known critical periods in the somatosensory system. This map is remarkably specific, taking a pinwheel-like form centered near the barrel center and aligned to the barrel cortex somatotopy. We suggest that this map may arise from intracortical mechanisms and demonstrate by simulation that the combination of spike-timing-dependent plasticity at synapses between layer 4 and layer 2/3 and realistic pad stimulation is sufficient to produce such a map. Its late emergence long after other classical maps suggests that experience-dependent map formation and refinement continue throughout adult life.

  17. A monomeric TIM-barrel structure from Pyrococcus furiosus is optimized for extreme temperatures.

    PubMed

    Repo, Heidi; Oeemig, Jesper S; Djupsjöbacka, Janica; Iwaï, Hideo; Heikinheimo, Pirkko

    2012-11-01

    The structure of phosphoribosyl anthranilate isomerase (TrpF) from the hyperthermophilic archaeon Pyrococcus furiosus (PfTrpF) has been determined at 1.75 Å resolution. The PfTrpF structure has a monomeric TIM-barrel fold which differs from the dimeric structures of two other known thermophilic TrpF proteins. A comparison of the PfTrpF structure with the two known bacterial thermophilic TrpF structures and the structure of a related mesophilic protein from Escherichia coli (EcTrpF) is presented. The thermophilic TrpF structures contain a higher proportion of ion pairs and charged residues compared with the mesophilic EcTrpF. These residues contribute to the closure of the central barrel and the stabilization of the barrel and the surrounding α-helices. In the monomeric PfTrpF conserved structural water molecules are mostly absent; instead, the structural waters are replaced by direct side-chain-main-chain interactions. As a consequence of these combined mechanisms, the P. furiosus enzyme is a thermodynamically stable and entropically optimized monomeric TIM-barrel enzyme which defines a good framework for further protein engineering for industrial applications.

  18. Functionally essential, invariant glutamate near the C-terminus of strand beta 5 in various (alpha/beta)8-barrel enzymes as a possible indicator of their evolutionary relatedness.

    PubMed

    Janecek, S; Baláz, S

    1995-08-01

    Twelve different (alpha/beta)8-barrel enzymes belonging to three structurally distinct families were found to contain, near the C-terminus of their strand beta 5, a conserved invariant glutamic acid residue that plays an important functional role in each of these enzymes. The search was based on the idea that a conserved sequence region of an (alpha/beta)8-barrel enzyme should be more or less conserved also in the equivalent part of the structure of the other enzymes with this folding motif owing to their mutual evolutionary relatedness. For this purpose, the sequence region around the well conserved fifth beta-strand of alpha-amylase containing catalytic glutamate (Glu230, Aspergillus oryzae alpha-amylase numbering), was used as the sequence-structural template. The isolated sequence stretches of the 12 (alpha/beta)8-barrels are discussed from both the sequence-structural and the evolutionary point of view, the invariant glutamate residue being proposed to be a joining feature of the studied group of enzymes remaining from their ancestral (alpha/beta)8-barrel.

  19. Wireline-rotary air coring of the Bandelier Tuff, Los Alamos, New Mexico

    USGS Publications Warehouse

    Teasdale, W.E.; Pemberton, R.R.

    1984-01-01

    This paper describes experiments using wireline-rotary air-coring techniques conducted in the Bandelier Tuff using a modified standard wireline core-barrel system. The modified equipment was used to collect uncontaminated cores of unconsolidated ash and indurated tuff at Los Alamos, New Mexico. Core recovery obtained from the 210-foot deep test hole was about 92 percent. A standard HQ-size, triple-tube wireline core barrel (designed for the passage of liquid drilling fluids) was modified for air coring as follows: (1) Air passages were milled in the latch body part of the head assembly; (2) the inside dimension of the outer core barrel tube was machined and honed to provide greater clearance between the inner and outer barrels; (3) oversized reaming devices were added to the outer core barrel and the coring bit to allow more clearance for air and cuttings return; (4) the eight discharge ports in the coring bit were enlarged. To control airborne-dust pollution, a dust-and-cuttings discharge subassembly, designed and built by project personnel, was used. (USGS)

  20. U.S. Geological Survey 2002 petroleum resource assessment of the National Petroleum Reserve in Alaska (NPRA)

    USGS Publications Warehouse

    Bird, K.J.; Houseknecht, D.W.

    2002-01-01

    A new USGS assessment concludes that NPRA holds signicantly greater petroleum resources than previously estimated. Technically recoverable, undiscovered oil beneath the Federal part of NPRA likely ranges between 5.9 and 13.2 billion barrels, with a mean (expected) value of 9.3 billion barrels. An estimated 1.3 to 5.6 billion barrels of those technically recoverable oil resources is economically recoverable at market prices of $22 to $30 per barrel. Technically recoverable, undiscovered nonassociated natural gas for the same area likely ranges between 39.1 and 83.2 trillion cubic feet, with a mean (expected) value of 59.7 trillion cubic feet. The economic viability of this gas will depend on the availability of a natural-gas pipeline for transport to market.

  1. Early stages in the biogenesis of eukaryotic β-barrel proteins.

    PubMed

    Jores, Tobias; Rapaport, Doron

    2017-09-01

    The endosymbiotic organelles mitochondria and chloroplasts harbour, similarly to their prokaryotic progenitors, β-barrel proteins in their outer membrane. These proteins are encoded on nuclear DNA, translated on cytosolic ribosomes and imported into their target organelles by a dedicated machinery. Recent studies have provided insights into the import into the organelles and the membrane insertion of these proteins. Although the cytosolic stages of their biogenesis are less well defined, it is speculated that upon their synthesis, chaperones prevent β-barrel proteins from aggregation and keep them in an import-competent conformation. In this Review, we summarize the current knowledge about the biogenesis of β-barrel proteins, focusing on the early stages from the translation on cytosolic ribosomes to the recognition on the surface of the organelle. © 2017 Federation of European Biochemical Societies.

  2. Single-Cylinder Oil-Control Tests of Porous Chrome-Plated Cylinder Barrels for Radial Air-Cooled Engines

    DTIC Science & Technology

    1946-01-01

    plating, it will affect a choke as desired in the cylinder. When the clearance between the anode and the cathode (cylinder barrel) is decreased, an...National Advisory Commltteo for Aeronautics, Cltivel« oid , Ohio. RSFEFKICE3 1. Johnson, Robert L., wad Anderson, Roy I.: S.’.nglo-Cylindor Engine Tests...plating a choke in the bore. Choice la obtained by decreasing the clear- ance between the anode and the cylinder barrel ( cathode ). Taper on anode la

  3. Rainfall thresholds for the initiation of debris flows at La Honda, California

    USGS Publications Warehouse

    Wilson, R.C.; Wieczorek, G.F.

    1995-01-01

    A simple numerical model, based on the physical analogy of a leaky barrel, can simulate significant features of the interaction between rainfall and shallow-hillslope pore pressures. The leaky-barrel-model threshold is consistent with, but slightly higher than, an earlier, purely empirical, threshold. The number of debris flows triggered by a storm can be related to the time and amount by which the leaky-barrel-model response exceeded the threshold during the storm. -from Authors

  4. Hartwell Lake Project, Savannah River, Georgia and South Carolina. Rehabilitation of Clemson Upper Diversion Dam. Construction Foundation Report. Volume 2. Appendices B thru E

    DTIC Science & Technology

    1989-08-01

    remove by gravity -washed out 585.8 i -- 89. 2 gneiss from inner - ibarrel Bottom of hole 89.2’ Tape depth 89.0’ 90 -0 I-Note: 6-7-84 water level after...barrel and5 _-_89.3 washed all meterial Bottom of hole 89.3’ left in outer barrel- 90 out of barrel befor- drilling for pull I Tape depth 89.0’ Note

  5. Dynamic Uniaxial Tensile Loading of Vector Polymers

    DTIC Science & Technology

    2011-11-01

    to apply the loading velocity to the strip at x = 0 after impact by a steel slug projectile. The flange has two sets of grooves. One set, denoted as...travels down the barrel . The strip is clamped to the outside of the barrel at x = L. A Photron SA1 high-speed video camera with a framing rate of...nominal stress. Equation 1 is expressed in terms of particle displacement to obtain the wave equation Flange Gun Barrel Rubber Strip Clamp x = 0

  6. Evaluating Long-Term Impacts of Soil-Mixing Source-Zone Treatment using Cryogenic Core Collection

    DTIC Science & Technology

    2017-06-01

    to (a) coring equipment freezing downhole, (b) freezing or binding of the core sample in barrel, and ( c ) running out of LN in the vicinity of sampling...encountered due to (a) coring equipment freezing downhole, (b) freezing or binding of the core sample in barrel, and ( c ) running out of LN in the...equipment freezing downhole, (b) freezing or binding of the core sample in barrel, and ( c ) running out of LN in the vicinity of sampling. Downhole

  7. On the Behaviour of Porcine Adipose and Skeletal Muscle Tissues under Shock Compression

    DTIC Science & Technology

    2012-09-01

    74 (breech pressure) shots. Secondly, a smaller vacuum pump evacuates the air within both the barrel of the gun and a sealed section mounted at the end...pressure. To fire the gun this cavity was rapidly evacuated, allowing first the disk adjacent to the breech and then that adjacent to the barrel to...of the gun , i.e. the barrel section. Such action allowed for a much stronger vacuum to be created than within the rearward expansion chamber and

  8. Characterization and Discrimination of Large Caliber Gun Blast and Flash Signatures

    DTIC Science & Technology

    2011-10-01

    from one end of a barrel (the muzzle) by the application of force at the other end. In conventional guns , force is provided by the combustion of a...projectile begins to accelerate down the barrel ; this is known as shot start. As the projectile traverses the gun barrel and additional volume becomes...flash that is used today resulted from this program’s report. Visible and ultraviolet (UV) spectra of 20 mm and .50 caliber machine gun firings were

  9. A Study of the Engraving of the M855 5.56-mm Projectile

    DTIC Science & Technology

    2009-03-01

    handgun , and shotgun cleaning kit and bore brushes. At the start of a test, a bullet was placed into the barrel so that it made contact with the...interaction with the forcing cone, it cannot be determined if that material remained on the forcing cone or was transferred further down the barrel ...The load vs. displacement plots of figures 6–12 do not show any load spikes further down the barrel to indicate a build up and release of material

  10. The United States Remains Unprepared for Oil Import Disruptions. Volume II. Detailed Review of Current Emergency Programs and Alternative Approaches.

    DTIC Science & Technology

    1981-09-29

    limited to one tank of gas per week, while 40 percent could fill up twice. If gas stations were closed on Sundays, the percentages, respectively, would be...Mixing Gas and Coal in Existing Electric Facilities X-1 Establishing a Strategic Natural Gas Reserve X-2 Exploring the Possibility of Negotiating...Advisory Group LNG Liquefied Natural Gas MBD Thousand Barrels Per Day MER Maximum Efficient Rate of Production MMB Million Barrels MMBD Million Barrels

  11. Summary of types of radiation belt electron precipitation observed by BARREL

    NASA Astrophysics Data System (ADS)

    Halford, Alexa

    2016-07-01

    The Balloon Array for Relativistic Radiation belt Electron Loss (BARREL) was able to infer precipitation of radiation belt electrons on multiple time scales and due to multiple loss mechanisms. One storm will be specifically highlighted which occurred on 26 January 2013 when a solar wind shock hit the Earth. Although MeV electrons were observed to be lost due to an EMIC wave event [Zhang et al in prep], and multiple periods of electron loss during substorms were observed [Rae et al submitted JGR, Mann et al in prep], we will consider an event period where loss associated with multiple time scales, and thus possibly different loss mechanisms was observed from 1000 - 1200 UT on 26 January 2013. At about 1005 UT on 26 January 2013 an injection of radiation belt electrons followed by drift echoes for energies of ˜80 - 400 keV. BARREL observed X-rays with energies less than 180 keV associated with multiple temporal structures during the drift echo event period. The Van Allen Probes were at similar L-values but upwards of 2 hours away in MLT. Upper band chorus and ULF waves were observed during the event period. Throughout the beginning of the event period, microbursts were clearly observed. During this time lower band chorus waves as well as time domain structures were observed at Van Allen Probe A located upwards of 2 hours away in MLT. This large difference in MLT meant that neither potential loss mechanism was able to be clearly associated with the microbursts. As the lower band chorus and time domain structures were observed to recede, the microbursts were also observed to subside. ULF time scale modulation of the X-rays was also observed throughout most of the event period. We will examine if the ULF waves are the cause of the precipitation themselves, or are modulating the loss of particles from a secondary loss mechanism [Brito et al 2015 JGR, Rae et al Submitted JGR]. Although the 100s ms and ULF time scales are clearly observed, there is an ˜20 minute overarching structure observed in the X-rays at BARREL. This longer time scale appears to match the drift period of the ˜300 keV electrons observed by the Van Allen probes. However the inferred energy of the precipitating electrons is ˜150 keV. It is unclear what may be causing the ˜20 minute structure in the X-rays. At the time of writing this abstract, it is unclear if the drifting of the 300 keV electrons is related to the precipitation of the lower energy electrons (< 180 keV) or if it is just coincidence that they have the same temporal structure.

  12. Alternative Splice Variants in TIM Barrel Proteins from Human Genome Correlate with the Structural and Evolutionary Modularity of this Versatile Protein Fold

    PubMed Central

    Ochoa-Leyva, Adrián; Montero-Morán, Gabriela; Saab-Rincón, Gloria; Brieba, Luis G.; Soberón, Xavier

    2013-01-01

    After the surprisingly low number of genes identified in the human genome, alternative splicing emerged as a major mechanism to generate protein diversity in higher eukaryotes. However, it is still not known if its prevalence along the genome evolution has contributed to the overall functional protein diversity or if it simply reflects splicing noise. The (βα)8 barrel or TIM barrel is one of the most frequent, versatile, and ancient fold encountered among enzymes. Here, we analyze the structural modifications present in TIM barrel proteins from the human genome product of alternative splicing events. We found that 87% of all splicing events involved deletions; most of these events resulted in protein fragments that corresponded to the (βα)2, (βα)4, (βα)5, (βα)6, and (βα)7 subdomains of TIM barrels. Because approximately 7% of all the splicing events involved internal β-strand substitutions, we decided, based on the genomic data, to design β-strand and α-helix substitutions in a well-studied TIM barrel enzyme. The biochemical characterization of one of the chimeric variants suggests that some of the splice variants in the human genome with β-strand substitutions may be evolving novel functions via either the oligomeric state or substrate specificity. We provide results of how the splice variants represent subdomains that correlate with the independently folding and evolving structural units previously reported. This work is the first to observe a link between the structural features of the barrel and a recurrent genetic mechanism. Our results suggest that it is reasonable to expect that a sizeable fraction of splice variants found in the human genome represent structurally viable functional proteins. Our data provide additional support for the hypothesis of the origin of the TIM barrel fold through the assembly of smaller subdomains. We suggest a model of how nature explores new proteins through alternative splicing as a mechanism to diversify the proteins encoded in the human genome. PMID:23950966

  13. 29 CFR 1910.212 - General requirements for all machines.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Alligator shears. (d) Power presses. (e) Milling machines. (f) Power saws. (g) Jointers. (h) Portable power tools. (i) Forming rolls and calenders. (4) Barrels, containers, and drums. Revolving drums, barrels...

  14. Resolution of Port/Starboard Ambiguity Using a Linear Array of Triplets and a Twin-Line Planar Array

    DTIC Science & Technology

    2016-06-01

    STARBOARD AMBIGUITY USING A LINEAR ARRAY OF TRIPLETS AND A TWIN- LINE PLANAR ARRAY by Stilson Veras Cardoso June 2016 Thesis Advisor...OF TRIPLETS AND A TWIN-LINE PLANAR ARRAY 5. FUNDING NUMBERS 6. AUTHOR(S) Stilson Veras Cardoso 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...A LINEAR ARRAY OF TRIPLETS AND A TWIN-LINE PLANAR ARRAY Stilson Veras Cardoso Civilian, Brazilian Navy B.S., University of Brasília, 1993

  15. 1. Exterior, corner, wall, and barrel of cannon used to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Exterior, corner, wall, and barrel of cannon used to protect corner of building from cart wheels. 1960. - Jefferson Barracks, Brick & Stone Powder Magazine, Jefferson Barracks, St. Louis County, MO

  16. Wine evolution and spatial distribution of oxygen during storage in high-density polyethylene tanks.

    PubMed

    del Alamo-Sanza, María; Laurie, V Felipe; Nevares, Ignacio

    2015-04-01

    Porous plastic tanks are permeable to oxygen due to the nature of the polymers with which they are manufactured. In the wine industry, these types of tanks are used mainly for storing wine surpluses. Lately, their use in combination with oak pieces has also been proposed as an alternative to mimic traditional barrel ageing. In this study, the spatial distribution of dissolved oxygen in a wine-like model solution, and the oxygen transfer rate (OTR) of high-density polyethylene tanks (HDPE), was analysed by means of a non-invasive opto-luminescence detector. Also, the chemical and sensory evolution of red wine, treated with oak pieces, and stored in HDPE tanks was examined and compared against traditional oak barrel ageing. The average OTR calculated for these tanks was within the commonly accepted amounts reported for new barrels. With regards to wine evolution, a number of compositional and sensory differences were observed between the wines aged in oak barrels and those stored in HDPE tanks with oak barrel alternatives. The use of HDPE tanks in combination with oak wood alternatives is a viable alternative too for ageing wine. © 2014 Society of Chemical Industry.

  17. Effect of micro-oxygenation and wood type on the phenolic composition and color of an aged red wine.

    PubMed

    Sánchez-Iglesias, Montserrat; González-Sanjosé, Ma Luisa; Pérez-Magariño, Silvia; Ortega-Heras, Miriam; González-Huerta, Carlos

    2009-12-23

    Many studies have recently been published focused on the effects of micro-oxygenation on the quality of wines, its application modes, and doses, etc. However, there are still few scientific papers on how previously micro-oxygenated wines perform during storage or barrel aging. This study focused on the evolution of the phenolic composition, especially of anthocyanins, and color, together with astringency and tannins, during micro-oxygenation before barrel aging. In addition, to evaluate whether wine evolution during aging depends on barrel type, wines were aged in four different oak barrel types. Tempranillo wines, some micro-oxygenated before malolactic fermentation and others not, were aged for 12 months in American, French, Central European, and Spanish oak, following wine evolution during that period. The study was carried out for two consecutive vintages. Results showed that all wines evolved similarly; therefore, the micro-oxygenation treatment neither accelerated nor delayed the typical changes of aging. Slightly different evolutions were detected according to the barrel wood type, whether or not the wine was micro-oxygenated. The varied evolutions must therefore be associated with the differences from each oak type (structure, grain and density, composition, etc.).

  18. TIM Barrel Protein Structure Classification Using Alignment Approach and Best Hit Strategy

    NASA Astrophysics Data System (ADS)

    Chu, Jia-Han; Lin, Chun Yuan; Chang, Cheng-Wen; Lee, Chihan; Yang, Yuh-Shyong; Tang, Chuan Yi

    2007-11-01

    The classification of protein structures is essential for their function determination in bioinformatics. It has been estimated that around 10% of all known enzymes have TIM barrel domains from the Structural Classification of Proteins (SCOP) database. With its high sequence variation and diverse functionalities, TIM barrel protein becomes to be an attractive target for protein engineering and for the evolution study. Hence, in this paper, an alignment approach with the best hit strategy is proposed to classify the TIM barrel protein structure in terms of superfamily and family levels in the SCOP. This work is also used to do the classification for class level in the Enzyme nomenclature (ENZYME) database. Two testing data sets, TIM40D and TIM95D, both are used to evaluate this approach. The resulting classification has an overall prediction accuracy rate of 90.3% for the superfamily level in the SCOP, 89.5% for the family level in the SCOP and 70.1% for the class level in the ENZYME. These results demonstrate that the alignment approach with the best hit strategy is a simple and viable method for the TIM barrel protein structure classification, even only has the amino acid sequences information.

  19. Detailed design of a lattice composite fuselage structure by a mixed optimization method

    NASA Astrophysics Data System (ADS)

    Liu, D.; Lohse-Busch, H.; Toropov, V.; Hühne, C.; Armani, U.

    2016-10-01

    In this article, a procedure for designing a lattice fuselage barrel is developed. It comprises three stages: first, topology optimization of an aircraft fuselage barrel is performed with respect to weight and structural performance to obtain the conceptual design. The interpretation of the optimal result is given to demonstrate the development of this new lattice airframe concept for the fuselage barrel. Subsequently, parametric optimization of the lattice aircraft fuselage barrel is carried out using genetic algorithms on metamodels generated with genetic programming from a 101-point optimal Latin hypercube design of experiments. The optimal design is achieved in terms of weight savings subject to stability, global stiffness and strain requirements, and then verified by the fine mesh finite element simulation of the lattice fuselage barrel. Finally, a practical design of the composite skin complying with the aircraft industry lay-up rules is presented. It is concluded that the mixed optimization method, combining topology optimization with the global metamodel-based approach, allows the problem to be solved with sufficient accuracy and provides the designers with a wealth of information on the structural behaviour of the novel anisogrid composite fuselage design.

  20. 27 CFR 479.192 - Commerce in firearms and ammunition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES..., machine guns, short-barreled shotguns, or short-barreled rifles, see 18 U.S.C. Chapter 44, and Part 478 of...

  1. 27 CFR 479.192 - Commerce in firearms and ammunition.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES..., machine guns, short-barreled shotguns, or short-barreled rifles, see 18 U.S.C. Chapter 44, and Part 478 of...

  2. 27 CFR 479.192 - Commerce in firearms and ammunition.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES..., machine guns, short-barreled shotguns, or short-barreled rifles, see 18 U.S.C. Chapter 44, and Part 478 of...

  3. 27 CFR 479.192 - Commerce in firearms and ammunition.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES..., machine guns, short-barreled shotguns, or short-barreled rifles, see 18 U.S.C. Chapter 44, and Part 478 of...

  4. 27 CFR 479.192 - Commerce in firearms and ammunition.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES..., machine guns, short-barreled shotguns, or short-barreled rifles, see 18 U.S.C. Chapter 44, and Part 478 of...

  5. index

    Science.gov Websites

    ) Control panel layout and wiring diagram. (Rev. 6, 12/14/06). 2. SUMMARY AND TEST INFORMATION Barrel Movement Test (*.pdf) Summary of data collected during barrel movement test in June, 2005 (DRAFT, 6/27/05

  6. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... FRUITS, VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.6 Classes of barrels for... other dry commodities other than cranberries, are hereby divided into two classes as follows: (a) Class...

  7. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... FRUITS, VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.6 Classes of barrels for... other dry commodities other than cranberries, are hereby divided into two classes as follows: (a) Class...

  8. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FRUITS, VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.6 Classes of barrels for... other dry commodities other than cranberries, are hereby divided into two classes as follows: (a) Class...

  9. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... FRUITS, VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.6 Classes of barrels for... other dry commodities other than cranberries, are hereby divided into two classes as follows: (a) Class...

  10. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FRUITS, VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.6 Classes of barrels for... other dry commodities other than cranberries, are hereby divided into two classes as follows: (a) Class...

  11. Hypervelocity cutting machine and method

    DOEpatents

    Powell, J.R.; Reich, M.

    1996-11-12

    A method and machine are provided for cutting a workpiece such as concrete. A gun barrel is provided for repetitively loading projectiles therein and is supplied with a pressurized propellant from a storage tank. A thermal storage tank is disposed between the propellant storage tank and the gun barrel for repetitively receiving and heating propellant charges which are released in the gun barrel for repetitively firing projectiles therefrom toward the workpiece. In a preferred embodiment, hypervelocity of the projectiles is obtained for cutting the concrete workpiece by fracturing thereof. 10 figs.

  12. The Barrel vascular reconstruction device for endovascular coiling of wide-necked intracranial aneurysms: a multicenter, prospective, post-marketing study.

    PubMed

    Gory, Benjamin; Blanc, Raphaël; Turjman, Francis; Berge, Jérôme; Piotin, Michel

    2018-02-02

    The Barrel vascular reconstruction device (Barrel VRD) is a novel stent with design features that allow endovascular coiling of wide-necked bifurcation aneurysms while preserving adjacent branches, without necessitating dual stent implantation. This study aimed to assess the safety and effectiveness of the Barrel VRD at 12-month follow-up. The Barrel VRD trial is a prospective, multicenter, observational post-marketing registry evaluating the use of the Barrel VRD for treatment of wide-necked bifurcation aneurysms. The primary effectiveness endpoint was successful aneurysm treatment measured by digital subtraction angiography with a Raymond-Roy occlusion grade of 1 or 2 in the absence of retreatment, parent artery stenosis (>50%), or target aneurysm rupture at 12 months. The primary safety endpoint was the absence of neurological death or major stroke at 12 months. Twenty patients were enrolled from December 2013 to December 2014. The device was implanted in 19 patients with 19 aneurysms (8 middle cerebral artery, 4 anterior communicating artery, 1 internal carotid artery terminus, 4 basilar artery aneurysms; mean dome height 5.7±1.91 mm; mean neck length 4.8±1.35 mm, mean dome-to-neck ratio 1.6±2.0). Coiling was performed in all cases. The primary effectiveness endpoint was achieved in 78.9% of subjects (15/19; 12 complete occlusions, 3 neck remnants), and the primary safety endpoint was 5.3% (1/19). This prospective study demonstrates that the Barrel VRD device resulted in ~80% occlusion rates and ~5% rates of neurological complications at 1 year after endovascular treatment of wide-necked bifurcation intracranial aneurysms. REGISTERED CLINICAL TRIAL: NCT02125097;Results. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Quantitative/Statistical Approach to Bullet-to-Firearm Identification with Consecutively Manufactured Barrels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peter Striupaitis; R.E. Gaensslen

    Efforts to use objective image comparison and bullet scanning technologies to distinguish bullets from consecutively manufactured handgun barrels from two manufacturers gave mixed results. The ability of a technology to reliably distinguish between matching and non-matching bullets, where the non-matching bullets were as close in pattern to the matching ones as is probably possible, would provide evidence that the distinctions could be made ''objectively'', and independently of human eyes. That evidence is identical or very close to what seems to be needed to satisfy Daubert standards. It is fair to say that the FTI IBIS image comparison technology correctly distinguishedmore » between all the Springfield barrel bullets, and between most but not all of the HiPoint barrel bullets. In the HiPoint cases that were not distinguished 100% of the time, they would he distinguished correctly at least 83% of the time. These results, although obviously limited to the materials used in the comparisons, provide strong evidence that barrel-to-bullet matching is objectively reliable. The results with SciClops were less compelling. The results do not mean that bullet-to-barrel matching is not objectively reliable--rather, they mean that this version of the particular technology could not quite distinguish between these extremely similar yet different bullets as well as the image comparison technology did. In a number of cases, the numerical results made the correct distinctions, although they were close to one another. It is hard to say from this data that this technology differs in its ability to make distinctions between the manufacturers, because the results are very similar with both. The human examiner results were as expected. We did not expect any misidentifications, and there were not any. It would have been preferable to have a higher return rate, and thus more comparisons in the overall sample. As noted, the ''consecutively manufactured barrel exercise'' has been done before, with the same outcome.« less

  14. In vivo roles of BamA, BamB and BamD in the biogenesis of BamA, a core protein of the β-barrel assembly machine of Escherichia coli.

    PubMed

    Misra, Rajeev; Stikeleather, Ryan; Gabriele, Rebecca

    2015-03-13

    Assembly of the β-barrel outer membrane proteins (OMPs) is an essential cellular process in Gram-negative bacteria and in the mitochondria and chloroplasts of eukaryotes--two organelles of bacterial origin. Central to this process is the conserved β-barrel OMP that belongs to the Omp85 superfamily. In Escherichia coli, BamA is the core β-barrel OMP and, together with four outer membrane lipoproteins, BamBCDE, constitutes the β-barrel assembly machine (BAM). In this paper, we investigated the roles of BamD, an essential lipoprotein, and BamB in BamA biogenesis. Depletion of BamD caused impairment in BamA biogenesis and cessation of cell growth. These defects of BamD depletion were partly reversed by single-amino-acid substitutions mapping within the β-barrel domain of BamA. However, in the absence of BamB, the positive effects of the β-barrel substitutions on BamA biogenesis under BamD depletion conditions were nullified. By employing a BamA protein bearing one such substitution, F474L, it was demonstrated that the mutant BamA protein could not only assemble without BamD but also facilitate the assembly of wild-type BamA expressed in trans. Based on these data, we propose a model in which the Bam lipoproteins, which are localized to the outer membrane by the BAM-independent Lol pathway, aid in the creation of new BAM complexes by serving as outer membrane receptors and folding factors for nascent BamA molecules. The newly assembled BAM holocomplex then catalyzes the assembly of substrate OMPs and BamA. These in vivo findings are corroborated by recently published in vitro data. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Effectiveness of low impact development practices in two urbanized watersheds: retrofitting with rain barrel/cistern and porous pavement.

    PubMed

    Ahiablame, Laurent M; Engel, Bernard A; Chaubey, Indrajeet

    2013-04-15

    The impacts of urbanization on hydrology and water quality can be minimized with the use of low impact development (LID) practices in urban areas. This study assessed the performance of rain barrel/cistern and porous pavement as retrofitting technologies in two urbanized watersheds of 70 and 40 km(2) near Indianapolis, Indiana. Six scenarios consisting of the watershed existing condition, 25% and 50% implementation of rain barrel/cistern and porous pavement, and 25% rain barrel/cistern combined with 25% porous pavement were evaluated using a proposed LID modeling framework and the Long-Term Hydrologic Impact Assessment (L-THIA)-LID model. The model was calibrated for annual runoff from 1991 to 2000, and validated from 2001 to 2010 for the two watersheds. For the calibration period, R(2) and NSE values were greater than 0.60 and 0.50 for annual runoff and streamflow. Baseflow was not calibrated in this study. During the validation period, R(2) and NSE values were greater than 0.50 for runoff and streamflow, and 0.30 for baseflow in the two watersheds. The various application levels of barrel/cistern and porous pavement resulted in 2-12% reduction in runoff and pollutant loads for the two watersheds. Baseflow loads slightly increased with increase in baseflow by more than 1%. However, reduction in runoff led to reduction in total streamflow and associated pollutant loads by 1-9% in the watersheds. The results also indicate that the application of 50% rain barrel/cistern, 50% porous pavement and 25% rain barrel/cistern combined with 25% porous pavement are good retrofitting options in these watersheds. The L-THIA-LID model can be used to inform management and decision-making for implementation of LID practices at the watershed scale. Copyright © 2013. Published by Elsevier Ltd.

  16. 6. Through/barrel view of Asylum (Western) Avenue bridge from west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Through/barrel view of Asylum (Western) Avenue bridge from west end looking east/downtown, facing southeast. - Asylum Avenue Viaduct, Spanning Second Creek & Southern Railroad at State Route 62, Knoxville, Knox County, TN

  17. 5. Through/barrel view of Asylum (Western) Avenue viaduct from downtown/east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Through/barrel view of Asylum (Western) Avenue viaduct from downtown/east end looking west, facing northwest. - Asylum Avenue Viaduct, Spanning Second Creek & Southern Railroad at State Route 62, Knoxville, Knox County, TN

  18. 33 CFR 87.1 - Need of assistance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; (c) Rockets or shells, throwing red stars fired one at a time at short intervals; (d) A signal made... burning tar barrel, oil barrel, etc.); (i) A rocket parachute flare or a hand flare showing a red light...

  19. 33 CFR 87.1 - Need of assistance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...; (c) Rockets or shells, throwing red stars fired one at a time at short intervals; (d) A signal made... burning tar barrel, oil barrel, etc.); (i) A rocket parachute flare or a hand flare showing a red light...

  20. 33 CFR 87.1 - Need of assistance.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...; (c) Rockets or shells, throwing red stars fired one at a time at short intervals; (d) A signal made... burning tar barrel, oil barrel, etc.); (i) A rocket parachute flare or a hand flare showing a red light...

  1. 33 CFR 87.1 - Need of assistance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...; (c) Rockets or shells, throwing red stars fired one at a time at short intervals; (d) A signal made... burning tar barrel, oil barrel, etc.); (i) A rocket parachute flare or a hand flare showing a red light...

  2. 33 CFR 87.1 - Need of assistance.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...; (c) Rockets or shells, throwing red stars fired one at a time at short intervals; (d) A signal made... burning tar barrel, oil barrel, etc.); (i) A rocket parachute flare or a hand flare showing a red light...

  3. 16. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARREL BEING LOWERED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARREL BEING LOWERED INTO PLACE FOR USE AS PIPE TUNNEL. INEEL PHOTO NUMBER NRTS-59-709. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  4. 18. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARRELS IN PLACE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARRELS IN PLACE TO BE USED AS PIPE TUNNELS. INEEL PHOTO NUMBER NRTS-59-925. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  5. 3. BARREL VIEW, LOOKING DOWN LENGTH OF BRIDGE, SHOWING MAKER'S ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. BARREL VIEW, LOOKING DOWN LENGTH OF BRIDGE, SHOWING MAKER'S PLATE, DECORATIVE SCROLLWORK AND URN FINIALS ON NORTHEAST PORTAL - "Forder" Pratt Through Truss Bridge, Spanning Maumee River at County Route 73, Antwerp, Paulding County, OH

  6. Distributed Wireless Monitoring System for Ullage and Temperature in Wine Barrels

    PubMed Central

    Zhang, Wenqi; Skouroumounis, George K.; Monro, Tanya M.; Taylor, Dennis K.

    2015-01-01

    This paper presents a multipurpose and low cost sensor for the simultaneous monitoring of temperature and ullage of wine in barrels in two of the most important stages of winemaking, that being fermentation and maturation. The distributed sensor subsystem is imbedded within the bung of the barrel and runs on battery for a period of at least 12 months and costs around $27 AUD for all parts. In addition, software was designed which allows for the remote transmission and easy visual interpretation of the data for the winemaker. Early warning signals can be sent when the temperature or ullage deviates from a winemakers expectations so remedial action can be taken, such as when topping is required or the movement of the barrels to a cooler cellar location. Such knowledge of a wine’s properties or storage conditions allows for a more precise control of the final wine quality. PMID:26266410

  7. Forwardly movable assembly for a firearm

    DOEpatents

    Crandall, David L [Idaho Falls, ID; Watson, Richard W [Blackfoot, ID

    2007-06-05

    A forwardly movable assembly for a firearm, the forwardly movable assembly adapted to be disposed in operative relationship relative to the other operative parts of a firearm, the firearm having in operative relationship each with one or more of the others: a barrel, a receiver, and at least one firing mechanism; the forwardly movable assembly comprising: the barrel and the receiver operatively connected with each other; a movable hand support structure to which at least one of the barrel and the receiver is connected, the barrel being movable therewith, the movable hand support structure being adapted to be gripped by an operator of the firearm; the forwardly movable assembly being adapted to be moved forward by an operator upon gripping the movable hand support structure and manually maneuvering the hand support structure forwardly; and, as the forwardly movable assembly is moved forwardly, the firing mechanism is completely disengaged therefrom and held substantially stationary relative thereto.

  8. Beta-Barrel Scaffold of Fluorescent Proteins: Folding, Stability and Role in Chromophore Formation

    PubMed Central

    Stepanenko, Olesya V.; Stepanenko, Olga V.; Kuznetsova, Irina M.; Verkhusha, Vladislav V.; Turoverov, Konstantin K.

    2013-01-01

    This review focuses on the current view of the interaction between the β-barrel scaffold of fluorescent proteins and their unique chromophore located in the internal helix. The chromophore originates from the polypeptide chain and its properties are influenced by the surrounding protein matrix of the β-barrel. On the other hand, it appears that a chromophore tightens the β-barrel scaffold and plays a crucial role in its stability. Furthermore, the presence of a mature chromophore causes hysteresis of protein unfolding and refolding. We survey studies measuring protein unfolding and refolding using traditional methods as well as new approaches, such as mechanical unfolding and reassembly of truncated fluorescent proteins. We also analyze models of fluorescent protein unfolding and refolding obtained through different approaches, and compare the results of protein folding in vitro to co-translational folding of a newly synthesized polypeptide chain. PMID:23351712

  9. Distributed Wireless Monitoring System for Ullage and Temperature in Wine Barrels.

    PubMed

    Zhang, Wenqi; Skouroumounis, George K; Monro, Tanya M; Taylor, Dennis

    2015-08-10

    This paper presents a multipurpose and low cost sensor for the simultaneous monitoring of temperature and ullage of wine in barrels in two of the most important stages of winemaking, that being fermentation and maturation. The distributed sensor subsystem is imbedded within the bung of the barrel and runs on battery for a period of at least 12 months and costs around $27 AUD for all parts. In addition, software was designed which allows for the remote transmission and easy visual interpretation of the data for the winemaker. Early warning signals can be sent when the temperature or ullage deviates from a winemakers expectations so remedial action can be taken, such as when topping is required or the movement of the barrels to a cooler cellar location. Such knowledge of a wine's properties or storage conditions allows for a more precise control of the final wine quality.

  10. Extruder system and method for treatment of a gaseous medium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Silvi, Norberto; Perry, Robert James; Singh, Surinder Prabhjot

    A system for treatment of a gaseous medium, comprises an extruder having a barrel. The extruder further comprises a first inlet port, a second inlet port, and a plurality of outlet ports coupled to the barrel. The first inlet port is configured for feeding a lean sorbent, the second inlet port is configured for feeding a gaseous medium, and the plurality of outlet ports are configured for releasing a plurality of components removed from the gaseous medium. Further, the extruder comprises a plurality of helical elements coupled to a plurality of kneading elements, mounted on a shaft, and disposed withinmore » the barrel. The barrel and the plurality of helical and kneading elements together form an absorption unit and a desorption unit. The first and second inlet ports are formed in the absorption unit and the plurality of outlet ports are formed in the absorption and desorption units.« less

  11. Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting β-barrel biogenesis.

    PubMed

    Wenz, Lena-Sophie; Ellenrieder, Lars; Qiu, Jian; Bohnert, Maria; Zufall, Nicole; van der Laan, Martin; Pfanner, Nikolaus; Wiedemann, Nils; Becker, Thomas

    2015-09-28

    Biogenesis of mitochondrial β-barrel proteins requires two preprotein translocases, the general translocase of the outer membrane (TOM) and the sorting and assembly machinery (SAM). TOM and SAM form a supercomplex that promotes transfer of β-barrel precursors. The SAM core complex contains the channel protein Sam50, which cooperates with Sam35 in precursor recognition, and the peripheral membrane protein Sam37. The molecular function of Sam37 has been unknown. We report that Sam37 is crucial for formation of the TOM-SAM supercomplex. Sam37 interacts with the receptor domain of Tom22 on the cytosolic side of the mitochondrial outer membrane and links TOM and SAM complexes. Sam37 thus promotes efficient transfer of β-barrel precursors to the SAM complex. We conclude that Sam37 functions as a coupling factor of the translocase supercomplex of the mitochondrial outer membrane. © 2015 Wenz et al.

  12. Pathogen detection in milk samples by ligation detection reaction-mediated universal array method.

    PubMed

    Cremonesi, P; Pisoni, G; Severgnini, M; Consolandi, C; Moroni, P; Raschetti, M; Castiglioni, B

    2009-07-01

    This paper describes a new DNA chip, based on the use of a ligation detection reaction coupled to a universal array, developed to detect and analyze, directly from milk samples, microbial pathogens known to cause bovine, ovine, and caprine mastitis or to be responsible for foodborne intoxication or infection, or both. Probes were designed for the identification of 15 different bacterial groups: Staphylococcus aureus, Streptococcus agalactiae, nonaureus staphylococci, Streptococcus bovis, Streptococcus equi, Streptococcus canis, Streptococcus dysgalactiae, Streptococcus parauberis, Streptococcus uberis, Streptococcus pyogenes, Mycoplasma spp., Salmonella spp., Bacillus spp., Campylobacter spp., and Escherichia coli and related species. These groups were identified based on the 16S rRNA gene. For microarray validation, 22 strains from the American Type Culture Collection or other culture collections and 50 milk samples were tested. The results demonstrated high specificity, with sensitivity as low as 6 fmol. Moreover, the ligation detection reaction-universal array assay allowed for the identification of Mycoplasma spp. in a few hours, avoiding the long incubation times of traditional microbiological identification methods. The universal array described here is a versatile tool able to identify milk pathogens efficiently and rapidly.

  13. Detailed Characteristics of Radiation Belt Electrons Revealed by CSSWE/REPTile Measurements

    NASA Astrophysics Data System (ADS)

    Zhang, K.; Li, X.; Schiller, Q.; Gerhardt, D. T.; Millan, R. M.

    2016-12-01

    The outer radiation belt electrons are highly dynamic. We study the detailed characteristics of the relativistic electrons in the outer belt using measurements from the Colorado Student Space Weather Experiment (CSSWE) mission, a low Earth orbit Cubesat, which transverses the radiation belt four times in one orbit ( 1.5 hr) and has the advantage of measuring the dynamic activities of the electrons including their rapid precipitations. Among the features of the relativistic electrons, we show the measured electron distribution as a function of geomagnetic activities and local magnetic field strength. Moreover, a specific precipitation band, which happened on 19 Jan 2013, is investigated based on the conjunctive measurement of CSSWE and the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL). In this precipitation band event, the net loss of the 0.58 1.63 MeV electrons (L=3.5 6) is estimated to account for 6.84% of the total electron content.

  14. All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences.

    PubMed

    Hayat, Sikander; Sander, Chris; Marks, Debora S; Elofsson, Arne

    2015-04-28

    Transmembrane β-barrels (TMBs) carry out major functions in substrate transport and protein biogenesis but experimental determination of their 3D structure is challenging. Encouraged by successful de novo 3D structure prediction of globular and α-helical membrane proteins from sequence alignments alone, we developed an approach to predict the 3D structure of TMBs. The approach combines the maximum-entropy evolutionary coupling method for predicting residue contacts (EVfold) with a machine-learning approach (boctopus2) for predicting β-strands in the barrel. In a blinded test for 19 TMB proteins of known structure that have a sufficient number of diverse homologous sequences available, this combined method (EVfold_bb) predicts hydrogen-bonded residue pairs between adjacent β-strands at an accuracy of ∼70%. This accuracy is sufficient for the generation of all-atom 3D models. In the transmembrane barrel region, the average 3D structure accuracy [template-modeling (TM) score] of top-ranked models is 0.54 (ranging from 0.36 to 0.85), with a higher (44%) number of residue pairs in correct strand-strand registration than in earlier methods (18%). Although the nonbarrel regions are predicted less accurately overall, the evolutionary couplings identify some highly constrained loop residues and, for FecA protein, the barrel including the structure of a plug domain can be accurately modeled (TM score = 0.68). Lower prediction accuracy tends to be associated with insufficient sequence information and we therefore expect increasing numbers of β-barrel families to become accessible to accurate 3D structure prediction as the number of available sequences increases.

  15. BamA POTRA Domain Interacts with a Native Lipid Membrane Surface.

    PubMed

    Fleming, Patrick J; Patel, Dhilon S; Wu, Emilia L; Qi, Yifei; Yeom, Min Sun; Sousa, Marcelo Carlos; Fleming, Karen G; Im, Wonpil

    2016-06-21

    The outer membrane of Gram-negative bacteria is an asymmetric membrane with lipopolysaccharides on the external leaflet and phospholipids on the periplasmic leaflet. This outer membrane contains mainly β-barrel transmembrane proteins and lipidated periplasmic proteins (lipoproteins). The multisubunit protein β-barrel assembly machine (BAM) catalyzes the insertion and folding of the β-barrel proteins into this membrane. In Escherichia coli, the BAM complex consists of five subunits, a core transmembrane β-barrel with a long periplasmic domain (BamA) and four lipoproteins (BamB/C/D/E). The BamA periplasmic domain is composed of five globular subdomains in tandem called POTRA motifs that are key to BAM complex formation and interaction with the substrate β-barrel proteins. The BAM complex is believed to undergo conformational cycling while facilitating insertion of client proteins into the outer membrane. Reports describing variable conformations and dynamics of the periplasmic POTRA domain have been published. Therefore, elucidation of the conformational dynamics of the POTRA domain in full-length BamA is important to understand the function of this molecular complex. Using molecular dynamics simulations, we present evidence that the conformational flexibility of the POTRA domain is modulated by binding to the periplasmic surface of a native lipid membrane. Furthermore, membrane binding of the POTRA domain is compatible with both BamB and BamD binding, suggesting that conformational selection of different POTRA domain conformations may be involved in the mechanism of BAM-facilitated insertion of outer membrane β-barrel proteins. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  16. Identification, amounts, and kinetics of extraction of C-glucosidic ellagitannins during wine aging in oak barrels or in stainless steel tanks with oak chips.

    PubMed

    Jourdes, Michaël; Michel, Julien; Saucier, Cédric; Quideau, Stéphane; Teissedre, Pierre-Louis

    2011-09-01

    The C-glucosidic ellagitannins are found in wine as a result of its aging in oak barrels or in stainless steel tanks with oak chips. Once dissolved in this slightly acidic solution, the C-glucosidic ellagitannins vescalagin can react with nucleophilic entities present in red wine, such as ethanol, catechin, and epicatechin, to generate condensed hybrid products such as the β-1-O-ethylvescalagin and the flavano-ellagitannins (acutissimin A/B and epiacutissimin A/B), respectively. During this study, we first monitored the extraction kinetic and the evolution of the eight major oak-derived C-glucosidic ellagitannins in red wines aged in oak barrels or in stainless steel tank with oak chips. Their extraction rates appeared to be faster during red wine aging in stainless steel tanks with oak chips. However, their overall concentrations in wines were found higher in the wine aged in barrels. The formation rates of the vescalagin-coupled derivatives were also estimated for the first time under both red wine aging conditions (i.e., oak barrels or stainless steel tanks with oak chips). As observed for the oak-native C-glucosidic ellagitannins, the concentrations of these vescalagin derivatives were higher in the red wine aged in oak barrels than in stainless steel tanks with oak chips. Despite these differences, their relative composition was similar under both red wine aging conditions. Finally, the impact of the oak chips size and toasting level on the C-glucosidic ellagitannins concentration in wine was also investigated.

  17. Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins.

    PubMed

    Heuck, Alexander; Schleiffer, Alexander; Clausen, Tim

    2011-03-11

    β-Barrel proteins are frequently found in the outer membrane of mitochondria, chloroplasts and Gram-negative bacteria. In Escherichia coli, these proteins are inserted in the outer membrane by the Bam (β-barrel assembly machinery) complex, a multiprotein machinery formed by the β-barrel protein BamA and the four peripheral membrane proteins BamB, BamC, BamD and BamE. The periplasmic part of BamA binds prefolded β-barrel proteins by a β-augmentation mechanism, thereby stabilizing the precursors prior to their membrane insertion. However, the role of the associated proteins within the Bam complex remains unknown. Here, we describe the crystal structure of BamB, a nonessential component of the Bam complex. The structure shows a typical eight-bladed β-propeller fold. Two sequence stretches of BamB were previously identified to be important for interaction with BamA. In our structure, both motifs are located in close proximity to each other and contribute to a conserved region forming a narrow groove on the top of the propeller. Moreover, crystal contacts reveal two interaction modes of how BamB might bind unfolded β-barrel proteins. In the crystal lattice, BamB binds to exposed β-strands by β-augmentation, whereas peptide stretches rich in aromatic residues can be accommodated in hydrophobic pockets located at the bottom of the propeller. Thus, BamB could simultaneously bind to BamA and prefolded β-barrel proteins, thereby enhancing the folding and membrane insertion capability of the Bam complex. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Development of a method to evaluate glutamate receptor function in rat barrel cortex slices.

    PubMed

    Lehohla, M; Russell, V; Kellaway, L; Govender, A

    2000-12-01

    The rat is a nocturnal animal and uses its vibrissae extensively to navigate its environment. The vibrissae are linked to a highly organized part of the sensory cortex, called the barrel cortex which contains spiny neurons that receive whisker specific thalamic input and distribute their output mainly within the cortical column. The aim of the present study was to develop a method to evaluate glutamate receptor function in the rat barrel cortex. Long Evans rats (90-160 g) were killed by cervical dislocation and decapitated. The brain was rapidly removed, cooled in a continuously oxygenated, ice-cold Hepes buffer (pH 7.4) and sliced using a vibratome to produce 0.35 mm slices. The barrel cortex was dissected from slices corresponding to 8.6 to 4.8 mm anterior to the interaural line and divided into rostral, middle and caudal regions. Depolarization-induced uptake of 45Ca2+ was achieved by incubating test slices in a high K+ (62.5 mM) buffer for 2 minutes at 35 degrees C. Potassium-stimulated uptake of 45Ca2+ into the rostral region was significantly lower than into middle and caudal regions of the barrel cortex. Glutamate had no effect. NMDA significantly increased uptake of 45Ca2+ into all regions of the barrel cortex. The technique is useful in determining NMDA receptor function and will be applied to study differences between spontaneously hypertensive rats (SHR) that are used as a model for attention deficit disorder and their normotensive control rats.

  19. DIOXIN FORMATION: THE BURN BARREL STUDY

    EPA Science Inventory

    The paper reports results from tests designed to examine some of the factors influencing the emissions of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDDs/Fs) from burn barrels. Results from PCDDs/Fs and polychlorinated biphenyls (PCBs) are reported, al...

  20. Allen Auditorium attic looking from southeast corner. Wine barrels with ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Allen Auditorium attic looking from southeast corner. Wine barrels with scrap used for counterweight material for lift up walls no longer in use - Sheldon Jackson College, Richard H. Allen Memorial Hall, Lincoln Street, Sitka, Sitka Borough, AK

  1. Wire ablation dynamics model and its application to imploding wire arrays of different geometries.

    PubMed

    Esaulov, A A; Kantsyrev, V L; Safronova, A S; Velikovich, A L; Shrestha, I K; Williamson, K M; Osborne, G C

    2012-10-01

    The paper presents an extended description of the amplified wire ablation dynamics model (WADM), which accounts in a single simulation for the processes of wire ablation and implosion of a wire array load of arbitrary geometry and wire material composition. To investigate the role of wire ablation effects, the implosions of cylindrical and planar wire array loads at the university based generators Cobra (Cornell University) and Zebra (University of Nevada, Reno) have been analyzed. The analysis of the experimental data shows that the wire mass ablation rate can be described as a function of the current through the wire and some coefficient defined by the wire material properties. The aluminum wires were found to ablate with the highest rate, while the copper ablation is the slowest one. The lower wire ablation rate results in a higher inward velocity of the ablated plasma, a higher rate of the energy coupling with the ablated plasma, and a more significant delay of implosion for a heavy load due to the ablation effects, which manifest the most in a cylindrical array configuration and almost vanish in a single-planar array configuration. The WADM is an efficient tool suited for wire array load design and optimization in wide parameter ranges, including the loads with specific properties needed for the inertial confinement fusion research and laboratory astrophysics experiments. The data output from the WADM simulation can be used to simplify the radiation magnetohydrodynamics modeling of the wire array plasma.

  2. Low-Cost Flow Visualization for a Supersonic Ejector

    NASA Technical Reports Server (NTRS)

    Olden, George W.; Lineberry, David M.; Linn, Christopher A. B.; Landrum, Brian D.; Hawk, Clark W.

    2005-01-01

    Shadowgraph techniques were applied to the cold flow ejector facility at the Propulsion Research Center at the University of Alabama in Huntsville. The setup for the experiments was relatively simple and was accomplished at very little cost. Series of shadowgraph images were taken of both dual nozzle and single nozzle strut based ejectors operating over a range of chamber pressures. The density gradient patterns in the shadowgraphs were compared to pressure data measured along the top and side walls of the mixing duct. The shadowgraph images showed the presence of barrel shocks emanating from the nozzles which at low pressures terminated in Mach disks and at higher pressures extended beyond the barrel shape and reflected off the walls of the duct. Based on pressure data from previous testing, reflected shocks were expected on the walls of the duct. The shadowgraph images confirmed the locations of these reflected shocks on the top wall of the duct. The shadowgraph images also showed the structure change which correlated to a change in pitch of the ejector noise, and corresponded to a change in trend of the duct wall pressure ratio distributions. The images produced from the setup provided insight into the complex flow behavior inside the ejector duct. In addition, the techniques were a valuable tool as an educational device for students.

  3. Large Format Arrays for Far Infrared and Millimeter Astronomy

    NASA Technical Reports Server (NTRS)

    Moseley, Harvey

    2004-01-01

    Some of the most compelling questions in modem astronomy are best addressed with submillimeter and millimeter observations. The question of the role of inflation in the early evolution of the universe is best addressed with large sensitive arrays of millimeter polarimeters. The study of the first generations of galaxies requires sensitive submillimeter imaging, which can help us to understand the history of energy release and nucleosynthesis in the universe. Our ability to address these questions is dramatically increasing, driven by dramatic steps in the sensitivity and size of available detector arrays. While the MIPS instrument on the SIRTF mission will revolutionize far infrared astronomy with its 1024 element array of photoconductors, thermal detectors remain the dominant technology for submillimeter and millimeter imaging and polarimetry. The last decade has seen the deployment of increasingly large arrays of bolometers, ranging from the 48 element arrays deployed on the KAO in the late 198Os, to the SHARC and SCUBA arrays in the 1990s. The past years have seen the deployment of a new generation of larger detector arrays in SHARC II (384 channels) and Bolocam (144 channels). These detectors are in operation and are beginning to make significant impacts on the field. Arrays of sensitive submillimeter bolometers on the SPIRE instrument on Herschel will allow the first large areas surveys of the sky, providing important insight into the evolution of galaxies. The next generation of detectors, led by SCUBA II, will increase the focal scale of these instruments by an order of magnitude. Two major missions are being planned by NASA for which further development of long wavelength detectors is essential, The SAFlR mission, a 10-m class telescope with large arrays of background limited detectors, will extend our reach into the epoch of initial galaxy formation. A major goal of modem cosmology is to test the inflationary paradigm in the early evolution of the universe. To this end, a mission is planned to detect the imprint of inflation on the CMB by precision measurement of its polarization. This work requires very large arrays of sensitive detectors which can provide unprecedented control of a wide range of systematic errors, given the small amplitude of the signal of interest. We will describe the current state of large format detector arrays, the performance requirements set by the new missions, and the different approaches being developed in the community to meet these requirements. We are confident that within a decade, these developments will lead to dramatic advances in our understanding of the evolution of the universe.

  4. Isolation and identification of phenolic compounds from rum aged in oak barrels by high-speed countercurrent chromatography/high-performance liquid chromatography-diode array detection-electrospray ionization mass spectrometry and screening for antioxidant activity.

    PubMed

    Regalado, Erik L; Tolle, Sebastian; Pino, Jorge A; Winterhalter, Peter; Menendez, Roberto; Morales, Ana R; Rodríguez, José L

    2011-10-14

    Beverages, especially wines are well-known to contain a variety of health-beneficial bioactive substances, mainly of phenolic nature which frequently exhibit antioxidant activity. Significant information is available about the separation and identification of polyphenols from some beverages by chromatographic and spectroscopic techniques, but considerably poor is chemical data related to the polyphenolic content in rums. In this paper, a method involving the all-liquid chromatographic technique of high-speed countercurrent chromatography (HSCCC) combined with high-performance liquid chromatography coupled with diode-array detection and electrospray ionization mass spectrometry (HPLC-DAD-ESI-MS(n)) has been successfully applied for separation and identification of phenolic compounds in an aged rum. Besides, the phenolic fraction (PF) was assayed for its antioxidant effects using three different free radical in vitro assays (DPPH·, RO(2)· and spontaneous lipid peroxidation (LPO) on brain homogenates) and on ferric reducing antioxidant power (FRAP). Results showed that PF potently scavenged DPPH and strongly scavenged peroxyl radicals compared to ascorbic acid and butylated hydroxytoluene (BHT); and almost equally inhibited LPO on brain homogenates subjected to spontaneous LPO when compared to quercetin. Moreover, PF also exhibited strong reducing power. This chemical analysis illustrates the rich array of phenols in the aged rum and represents a rapid and suitable method for the isolation and identification of phenolic compounds from mixtures of considerable complexity, achieving high purity and reproducibility with the use of two separation steps. Copyright © 2011 Elsevier B.V. All rights reserved.

  5. Free-piston cutting machine

    DOEpatents

    Ciccarelli, Gaby; Subudhi, Manomohan; Hall, Robert E.

    2000-01-01

    A cutting machine includes a gun barrel for receiving a projectile. A compression tube is disposed in flow communication with the barrel and includes a piston therein. A reservoir is disposed in flow communication with the tube and receives a first gas under pressure. A second gas fills the compression tube on a front face of the piston. And, the pressurized first gas is discharged into the tube on a back face of the piston to accelerate the piston through the tube for compressing the second gas, and in turn launching the projectile through the barrel to impact a workpiece.

  6. Hypervelocity cutting machine and method

    DOEpatents

    Powell, James R.; Reich, Morris

    1996-11-12

    A method and machine 14 are provided for cutting a workpiece 12 such as concrete. A gun barrel 16 is provided for repetitively loading projectiles 22 therein and is supplied with a pressurized propellant from a storage tank 28. A thermal storage tank 32,32A is disposed between the propellant storage tank 28 and the gun barrel 16 for repetitively receiving and heating propellant charges which are released in the gun barrel 16 for repetitively firing projectiles 22 therefrom toward the workpiece 12. In a preferred embodiment, hypervelocity of the projectiles 22 is obtained for cutting the concrete workpiece 12 by fracturing thereof.

  7. Development of the SSTL-300-S1 Composite Imager Barrel Structure

    NASA Astrophysics Data System (ADS)

    Hamar, Chris; Wood, Trevor; Alsami, Sami; Hallett, Ben

    2014-06-01

    The SSTL-300-S1 is the latest in the family of highly capable SSTL-300 platforms, providing high resolution imagery with all the existing mission performance of the heritage platform. In developing the product, SSTL has had to undertake the development of a composite imager barrel assembly, which forms the payload instrument's primary structure. Working to a nominal schedule of 24 months from requirements definition to structural qualification, the barrel's development philosophy has had to carefully balance the interdependent optical, structural and programmatic requirements. This paper provides a brief summary description of that development.

  8. Using a Gatling-Gun Configured Micro Pulsed Plasma Thruster as a Means to Control Micro Satellites with Extreme Precision

    DTIC Science & Technology

    2011-03-01

    machine gun , or distributor cap in an automobile. In a Gatling- Gun , when the barrel rotates it collects a round and as the round rotates, it comes...ejected and another is fed into the barrel . This design allows multiple rounds to be fired from the gun very quickly, and still prevent the barrel from...T6061 aluminum and had dimensions of (127 x 76.2 x76.2) mm, cross sectional area of 5.80644 *10-3 m2 and a volume of 7.374*10-4 m3. Using the volume

  9. Modular initiator with integrated optical diagnostic

    DOEpatents

    Alam, M Kathleen [Cedar Crest, NM; Schmitt, Randal L [Tijeras, NM; Welle, Eric J [Niceville, FL; Madden, Sean P [Arlington, MA

    2011-05-17

    A slapper detonator which integrally incorporates an optical wavequide structure for determining whether there has been degradation of the explosive in the explosive device that is to be initiated by the detonator. Embodiments of this invention take advantage of the barrel-like character of a typical slapper detonator design. The barrel assembly, being in direct contact with the energetic material, incorporates an optical diagnostic device into the barrel assembly whereby one can monitor the state of the explosive material. Such monitoring can be beneficial because the chemical degradation of the explosive plays an important in achieving proper functioning of a detonator/initiator device.

  10. Assessment of potential additions to conventional oil and gas resources of the world (outside the United States) from reserve growth, 2012

    USGS Publications Warehouse

    Klett, Timothy R.; Cook, Troy A.; Charpentier, Ronald R.; Tennyson, Marilyn E.; Attanasi, E.D.; Freeman, Phil A.; Ryder, Robert T.; Gautier, Donald L.; Verma, Mahendra K.; Le, Phuong A.; Schenk, Christopher J.

    2012-01-01

    The U.S. Geological Survey estimated volumes of technically recoverable, conventional petroleum resources resulting from reserve growth for discovered fields outside the United States that have reported in-place oil and gas volumes of 500 million barrels of oil equivalent or greater. The mean volumes were estimated at 665 billion barrels of crude oil, 1,429 trillion cubic feet of natural gas, and 16 billion barrels of natural gas liquids. These volumes constitute a significant portion of the world's oil and gas resources.

  11. Refolding, crystallization and preliminary X-ray crystallographic studies of the β-barrel domain of BamA, a membrane protein essential for outer membrane protein biogenesis.

    PubMed

    Ni, Dongchun; Yang, Kun; Huang, Yihua

    2014-03-01

    In Gram-negative bacteria, the assembly of outer membrane proteins (OMPs) requires a five-protein β-barrel assembly machinery (BAM) complex, of which BamA is an essential and evolutionarily conserved integral outer membrane protein. Here, the refolding, crystallization and preliminary X-ray crystallographic characterization of the β-barrel domain of BamA from Escherichia coli (EcBamA) are reported. Native and selenomethionine-substituted EcBamA proteins were crystallized at 16°C and X-ray diffraction data were collected to 2.6 and 3.7 Å resolution, respectively. The native crystals belonged to space group P21212, with unit-cell parameters a = 118.492, b = 159.883, c = 56.000 Å and two molecules in one asymmetric unit; selenomethionine-substituted protein crystals belonged to space group P4322, with unit-cell parameters a = b = 163.162, c = 46.388 Å and one molecule in one asymmetric unit. Initial phases for EcBamA β-barrel domain were obtained from a SeMet SAD data set. These preliminary X-ray crystallographic studies paved the way for further structural determination of the β-barrel domain of EcBamA.

  12. Oil release from Macondo well MC252 following the Deepwater Horizon accident.

    PubMed

    Griffiths, Stewart K

    2012-05-15

    Oil flow rates and cumulative discharge from the BP Macondo Prospect well in the Gulf of Mexico are calculated using a physically based model along with wellhead pressures measured at the blowout preventer (BOP) over the 86-day period following the Deepwater Horizon accident. Parameters appearing in the model are determined empirically from pressures measured during well shut-in and from pressures and flow rates measured the preceding day. This methodology rigorously accounts for ill-characterized evolution of the marine riser, installation and removal of collection caps, and any erosion at the wellhead. The calculated initial flow rate is 67,100 stock-tank barrels per day (stbd), which decays to 54,400 stbd just prior to installation of the capping stack and subsequent shut-in. The calculated cumulative discharge is 5.4 million stock-tank barrels, of which 4.6 million barrels entered the Gulf. Quantifiable uncertainties in these values are -9.3% and +7.5%, yielding a likely total discharge in the range from 4.9 to 5.8 million barrels. Minimum and maximum credible values of this discharge are 4.6 and 6.2 million barrels. Alternative calculations using the reservoir and sea-floor pressures indicate that any erosion within the BOP had little affect on cumulative discharge.

  13. Oil shale resources of the Uinta Basin, Utah and Colorado

    USGS Publications Warehouse

    ,

    2010-01-01

    The U.S. Geological Survey (USGS) recently completed a comprehensive assessment of in-place oil in oil shales of the Eocene Green River Formation of the Uinta Basin of eastern Utah and western Colorado. The oil shale interval was subdivided into eighteen roughly time-stratigraphic intervals, and each interval was assessed for variations in gallons per ton, barrels per acre, and total barrels in each township. The Radial Basis Function extrapolation method was used to generate isopach and isoresource maps, and to calculate resources. The total inplace resource for the Uinta Basin is estimated at 1.32 trillion barrels. This is only slightly lower than the estimated 1.53 trillion barrels for the adjacent Piceance Basin, Colorado, to the east, which is thought to be the richest oil shale deposit in the world. However, the area underlain by oil shale in the Uinta Basin is much larger than that of the Piceance Basin, and the average gallons per ton and barrels per acre values for each of the assessed oil shale zones are significantly lower in the depocenter in the Uinta Basin when compared to the Piceance Basin. These relations indicate that the oil shale resources in the Uinta Basin are of lower grade and are more dispersed than the oil shale resources of the Piceance Basin.

  14. Neurons in the barrel cortex turn into processing whisker and odor signals: a cellular mechanism for the storage and retrieval of associative signals

    PubMed Central

    Wang, Dangui; Zhao, Jun; Gao, Zilong; Chen, Na; Wen, Bo; Lu, Wei; Lei, Zhuofan; Chen, Changfeng; Liu, Yahui; Feng, Jing; Wang, Jin-Hui

    2015-01-01

    Associative learning and memory are essential to logical thinking and cognition. How the neurons are recruited as associative memory cells to encode multiple input signals for their associated storage and distinguishable retrieval remains unclear. We studied this issue in the barrel cortex by in vivo two-photon calcium imaging, electrophysiology, and neural tracing in our mouse model that the simultaneous whisker and olfaction stimulations led to odorant-induced whisker motion. After this cross-modal reflex arose, the barrel and piriform cortices connected. More than 40% of barrel cortical neurons became to encode odor signal alongside whisker signal. Some of these neurons expressed distinct activity patterns in response to acquired odor signal and innate whisker signal, and others encoded similar pattern in response to these signals. In the meantime, certain barrel cortical astrocytes encoded odorant and whisker signals. After associative learning, the neurons and astrocytes in the sensory cortices are able to store the newly learnt signal (cross-modal memory) besides the innate signal (native-modal memory). Such associative memory cells distinguish the differences of these signals by programming different codes and signify the historical associations of these signals by similar codes in information retrievals. PMID:26347609

  15. Universal Common Communication Substrate (UCCS) Specification; Universal Common Communication Substrate (UCCS) Implementation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Universal Common Communication Substrate (UCCS) is a low-level communication substrate that exposes high-performance communication primitives, while providing network interoperability. It is intended to support multiple upper layer protocol (ULPs) or programming models including SHMEM,UPC,Titanium,Co-Array Fortran,Global Arrays,MPI,GASNet, and File I/O. it provides various communication operations including one-sided and two-sided point-to-point, collectives, and remote atomic operations. In addition to operations for ULPs, it provides an out-of-band communication channel required typically required to wire-up communication libraries.

  16. An MF/HF radio array for radio and radar imaging of the ionosphere

    NASA Astrophysics Data System (ADS)

    Isham, Brett; Gustavsson, Bjorn; Belyey, Vasyl; Bullett, Terrence

    2016-07-01

    The Aguadilla Radio Array will be installed at the Interamerican University Aguadilla Campus, located in northwestern Puerto Rico. The array is intended for broad-band medium and high-frequency (MF/HF, roughly 2 to 25 MHz) radio and bistatic radar observations of the ionosphere. The main array consists of 20 antenna elements, arranged in a semi-random pattern providing a good distribution of baseline vectors, with 6-meter minimum spacing to eliminate spacial aliasing. A relocatable 6-element array is also being developed, in which each element consists of a crossed pair of active electric dipoles and all associated electronics for phase-coherent radio measurements. A primary scientific goal of the array is to create images of the region of ionospheric radio emissions stimulated by the new Arecibo Observatory high-power high-frequency radio transmitter. A second primary goal is the study of ionospheric structure and dynamics via coherent radar imaging of the ionosphere in collaboration with the University of Colorado / NOAA Versatile Interferometric Pulsed Ionospheric Radar (VIPIR), located at the USGS San Juan Observatory in Cayey, Puerto Rico. In addition to ionospheric research in collaboration with the Cayey and Arecibo Observatories, the goals of the project include the development of radio sounding, polarization, interferometry, and imaging techniques, and training of students at the university and high school levels.

  17. 40 CFR 63.562 - Standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... barrels per day; and (C) For 1997, 1,445,000 barrels per day. (ii) Maximum extent practicable means that... (thermocouples, pressure transducers, continuous emissions monitors (CEMS), etc.) variances. (i) The plan shall... monitoring equipment functions properly and variances of the control equipment and monitoring equipment are...

  18. Analysis of variance study of the rat cortical layer 4 barrel and layer 5b neurones

    PubMed Central

    Ito, Muneyuki; Kato, Miyuki

    2002-01-01

    Unique formation of rodent cortical barrels by layer 4 neurones attracts study of the sensory function of cortical input stage neurones (layer 4) compared with that of output stage neurones (layer 5). We have recorded extracellular responses from rat somatosensory cortical neurones to deflections of contralateral vibrissae. Thirty-two layer 4 barrel neurones and 29 layer 5b neurones were studied. Whisker stimulations were ramp-and-hold deflections with one of six different ramp velocities (100–2.5 mm s−1) and one of four different plateau amplitudes (2000–200 μm). Twenty-four (6 × 4) different stimulus forms were applied to the tip of a whisker trimmed to 10 mm in a predetermined order in stimulus cycles of 20–50 repetitions. Spike counts for a period of 2560 ms in 10 ms bins were summed to construct a matrix of 24 peristimulus histograms for each neurone. Twenty-four amplitude and 24 velocity values were computed from counts during the plateau and ramp phases, respectively. To determine the amplitude- and velocity dependence of a neurone, an amplitude F value (the ratio of variations among-/within-amplitude of the amplitude value) and a velocity F value (ratio of variations among-/within-velocity of the velocity value) were derived by analysis of variance. The amplitude F value of the layer 4 barrel neurones was greater than that of the layer 5b neurones (P < 0.0001). The velocity F value of the barrel neurones was smaller than that of the layer 5b neurones (P = 0.0226). The results suggests that barrel neurones and layer 5b neurones tend to detect amplitude and velocity components of whisker deflection, respectively. PMID:11882683

  19. Assessment of Residential Rain Barrel Water Quality and Use in Cincinnati, Ohio

    EPA Science Inventory

    The collection, storage, and reuse of rainwater collected in rain barrels from urban rooftop areas assists municipalities in achieving stormwater management objectives and in some areas also serves as an adjunct resource for domestic water supplies. In this study, rainwater reuse...

  20. 13. Interior view, grain tanks (bins). Barrel view of overhead ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Interior view, grain tanks (bins). Barrel view of overhead (fill) conveyor gallery bridge extending through tops of tanks just below roofs. Grain tripper straddles belt conveyor at mid-view. - Saint Anthony Elevator No. 3, 620 Malcom Avenue, Southeast, Minneapolis, Hennepin County, MN

  1. 15 CFR 241.1 - Capacities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.1 Capacities. (a) The capacities of the standard barrel for fruits, vegetables, and other dry commodities, other than cranberries, and its subdivisions, are... standard cranberry barrel and its subdivisions are as follows: Size Cubic inches Bushels 1 Quarts 1...

  2. 15 CFR 241.1 - Capacities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.1 Capacities. (a) The capacities of the standard barrel for fruits, vegetables, and other dry commodities, other than cranberries, and its subdivisions, are... standard cranberry barrel and its subdivisions are as follows: Size Cubic inches Bushels 1 Quarts 1...

  3. 15 CFR 241.1 - Capacities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.1 Capacities. (a) The capacities of the standard barrel for fruits, vegetables, and other dry commodities, other than cranberries, and its subdivisions, are... standard cranberry barrel and its subdivisions are as follows: Size Cubic inches Bushels 1 Quarts 1...

  4. 15 CFR 241.1 - Capacities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.1 Capacities. (a) The capacities of the standard barrel for fruits, vegetables, and other dry commodities, other than cranberries, and its subdivisions, are... standard cranberry barrel and its subdivisions are as follows: Size Cubic inches Bushels 1 Quarts 1...

  5. 15 CFR 241.1 - Capacities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.1 Capacities. (a) The capacities of the standard barrel for fruits, vegetables, and other dry commodities, other than cranberries, and its subdivisions, are... standard cranberry barrel and its subdivisions are as follows: Size Cubic inches Bushels 1 Quarts 1...

  6. Assessment of shale-oil resources of the Central Sumatra Basin, Indonesia, 2015

    USGS Publications Warehouse

    Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Tennyson, Marilyn E.; Mercier, Tracey J.; Brownfield, Michael E.; Pitman, Janet K.; Gaswirth, Stephanie B.; Leathers-Miller, Heidi M.

    2015-11-12

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 459 million barrels of shale oil, 275 billion cubic feet of associated gas, and 23 million barrels of natural gas liquids in the Central Sumatra Basin, Indonesia.

  7. 14. Interior view, grain tanks (bins). Barrel view of tunnel ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Interior view, grain tanks (bins). Barrel view of tunnel for load-out belt conveyor system located below tanks. Square, numbered spouts gravity-feed grain from overhead bins onto belt. - Saint Anthony Elevator No. 3, 620 Malcom Avenue, Southeast, Minneapolis, Hennepin County, MN

  8. Forming H-shaped and barrel-shaped nebulae with interacting jets

    NASA Astrophysics Data System (ADS)

    Akashi, Muhammad; Bear, Ealeal; Soker, Noam

    2018-04-01

    We conduct three-dimensional hydrodynamical simulations of two opposite jets with large opening angles launched from a binary stellar system into a previously ejected shell and show that the interaction can form barrel-like and H-like shapes in the descendant nebula. Such features are observed in planetary nebulae (PNe) and supernova remnants. Under our assumption, the dense shell is formed by a short instability phase of the giant star as it interacts with a stellar companion, and the jets are then launched by the companion as it accretes mass through an accretion disc from the giant star. We find that the H-shaped and barrel-shaped morphological features that the jets form evolve with time, and that there are complicated flow patterns, such as vortices, instabilities, and caps moving ahead along the symmetry axis. We compare our numerical results with images of 12 PNe, and show that jet-shell interaction that we simulate can account for the barrel-like or H-like morphologies that are observed in these PNe.

  9. Neural coding in barrel cortex during whisker-guided locomotion

    PubMed Central

    Sofroniew, Nicholas James; Vlasov, Yurii A; Hires, Samuel Andrew; Freeman, Jeremy; Svoboda, Karel

    2015-01-01

    Animals seek out relevant information by moving through a dynamic world, but sensory systems are usually studied under highly constrained and passive conditions that may not probe important dimensions of the neural code. Here, we explored neural coding in the barrel cortex of head-fixed mice that tracked walls with their whiskers in tactile virtual reality. Optogenetic manipulations revealed that barrel cortex plays a role in wall-tracking. Closed-loop optogenetic control of layer 4 neurons can substitute for whisker-object contact to guide behavior resembling wall tracking. We measured neural activity using two-photon calcium imaging and extracellular recordings. Neurons were tuned to the distance between the animal snout and the contralateral wall, with monotonic, unimodal, and multimodal tuning curves. This rich representation of object location in the barrel cortex could not be predicted based on simple stimulus-response relationships involving individual whiskers and likely emerges within cortical circuits. DOI: http://dx.doi.org/10.7554/eLife.12559.001 PMID:26701910

  10. Petroleum geology and total petroleum systems of the Widyan Basin and Interior Platform of Saudi Arabia and Iraq

    USGS Publications Warehouse

    Fox, James E.; Ahlbrandt, Thomas S.

    2002-01-01

    The Widyan Basin-Interior Platform Province (2023) ranks 17th in the world, exclusive of the United States, with 62.5 billion barrels of oil equivalent of total petroleum endowment (cumulative production plus remaining petroleum plus estimated mean undiscovered volumes). Mean estimates of undiscovered petroleum for the province, which includes both Paleozoic and Jurassic petroleum systems as well as portions of three additional total petroleum systems from adjacent provinces, are 21.22 billion barrels of oil, 94.75 trillion cubic feet of gas (15.8 billion barrels of oil equivalent), and 6.85 billion barrels of natural gas liquids. The Paleozoic total petroleum system is dominantly gas prone, whereas the volumetrically larger Jurassic total petroleum system is oil prone - resulting in the characterization of the province as an oil province. The discovery maturity for the province is a relatively low 31 percent, meaning that much of the province petroleum potential lies in the future.

  11. An allocation of undiscovered oil and gas resources to Big South Fork National Recreation Area and Obed Wild and Scenic River, Kentucky and Tennessee

    USGS Publications Warehouse

    Schenk, Christopher J.; Klett, Timothy R.; Charpentier, Ronald R.; Cook, Troy A.; Pollastro, Richard M.

    2006-01-01

    The U.S. Geological Survey (USGS) estimated volumes of undiscovered oil and gas resources that may underlie Big South Fork National Recreation Area and Obed Wild and Scenic River in Kentucky and Tennessee. Applying the results of existing assessments of undiscovered resources from three assessment units in the Appalachian Basin Province and three plays in the Cincinnati Arch Province that include these land parcels, the USGS allocated approximately (1) 16 billion cubic feet of gas, 15 thousand barrels of oil, and 232 thousand barrels of natural gas liquids to Big South Fork National Recreation Area; and (2) 0.5 billion cubic feet of gas, 0.6 thousand barrels of oil, and 10 thousand barrels of natural gas liquids to Obed Wild and Scenic River. These estimated volumes of undiscovered resources represent potential volumes in new undiscovered fields, but do not include potential additions to reserves within existing fields.

  12. Discovery and Biogeochemical Investigation of Chlorinated Industrial Waste in the Deep Ocean

    NASA Astrophysics Data System (ADS)

    Lemkau, K. L.; Kivenson, V. B.; Carmichael, C. A.; Aeppli, C.; Bagby, S. C.; Wentz, K.; Baxter, A.; Paul, B. G.; Pizarro, O.; Yoerger, D.; Reddy, C. M.; Valentine, D. L.

    2014-12-01

    Prior to the 1972 US ban on DDT use, dumping of solid waste from DDT manufacturing was permitted at two locations off the coast of Southern California. Between 1947 and 1961, 37-53 million liters of DDT waste (containing an estimated 350-700 metric tons of DDT) were disposed of at these deep-ocean dumpsites. In 2011 and 2013 we explored these sites with ROV Jason and AUV Sentry, discovering the remains of ~60 barrels scattered across dumpsite 2. Strikingly, many of these barrels were surrounded by distinctive white rings suggestive of microbial activity. We describe our identification and exploration of these sites and present results from chemical analysis of sediment cores collected around waste barrels. DDT and its degradation products (DDE, DDD and DDMU) were detectable at ng to μg per gram concentrations and showed spatial trends with both distance and depth around barrels. Analysis of microbial community DNA provides a first look at the role of microbiological processes in shaping these trends.

  13. Precision flyer initiator

    DOEpatents

    Frank, A.M.; Lee, R.S.

    1998-05-26

    A precision flyer initiator forms a substantially spherical detonation wave in a high explosive (HE) pellet. An explosive driver, such as a detonating cord, a wire bridge circuit or a small explosive, is detonated. A flyer material is sandwiched between the explosive driver and an end of a barrel that contains an inner channel. A projectile or ``flyer`` is sheared from the flyer material by the force of the explosive driver and projected through the inner channel. The flyer than strikes the HE pellet, which is supported above a second end of the barrel by a spacer ring. A gap or shock decoupling material delays the shock wave in the barrel from predetonating the HE pellet before the flyer. A spherical detonation wave is formed in the HE pellet. Thus, a shock wave traveling through the barrel fails to reach the HE pellet before the flyer strikes the HE pellet. The precision flyer initiator can be used in mining devices, well-drilling devices and anti-tank devices. 10 figs.

  14. Effects of GABAA receptor inhibition on response properties of barrel cortical neurons in C-fiber-depleted rats.

    PubMed

    Farazifard, Rasoul; Kiani, Roozbeh; Esteky, Hossein

    2005-07-19

    C-fiber depletion results in expansion of low threshold somatosensory mechanoreceptive fields. In this study, we investigated the role of intact C-fibers in GABAA-mediated inhibition in barrel cortical neurons. We used electronically controlled mechanical stimulation of whiskers to quantitatively examine the responses of barrel cells to whisker displacements. After systemic injection of picrotoxin neuronal responses were recorded at 5 min intervals for 20 min and then at 10 min intervals for 100 min. Picrotoxin injection caused a 3-fold increase in response magnitude of adjacent whisker stimulation and 1.4-fold increase in response magnitude of principal whisker stimulation with a maximum enhancement 50 min after the injection. There was no significant change in spontaneous activity following picrotoxin injection. The response enhancement and receptive field expansion observed in normal rats were completely absent in the C-fiber-depleted rats. These results suggest that the GABAA-mediated inhibition that modulates the receptive field functional organization of the barrel cortex depends on intact C-fibers.

  15. Precision flyer initiator

    DOEpatents

    Frank, Alan M.; Lee, Ronald S.

    1998-01-01

    A precision flyer initiator forms a substantially spherical detonation wave in a high explosive (HE) pellet. An explosive driver, such as a detonating cord, a wire bridge circuit or a small explosive, is detonated. A flyer material is sandwiched between the explosive driver and an end of a barrel that contains an inner channel. A projectile or "flyer" is sheared from the flyer material by the force of the explosive driver and projected through the inner channel. The flyer than strikes the HE pellet, which is supported above a second end of the barrel by a spacer ring. A gap or shock decoupling material delays the shock wave in the barrel from predetonating the HE pellet before the flyer. A spherical detonation wave is formed in the HE pellet. Thus, a shock wave traveling through the barrel fails to reach the HE pellet before the flyer strikes the HE pellet. The precision flyer initiator can be used in mining devices, well-drilling devices and anti-tank devices.

  16. The Use of the Time Average Visibility for Analyzing HERA-19 Commissioning Data: Effects of Non-Redundancy

    NASA Astrophysics Data System (ADS)

    Benefo, Roshan; Gallardo, Samavarti; Aguirre, James; La Plante, Paul; HERA Collaboration

    2018-01-01

    The Hydrogen Epoch of Reionization Array (HERA) is a radio telescope situated in South Africa designed to observe the universe from redshifts 13 through 6, in order to detect the emission of the 21 cm line from the hydrogen spin-flip transition. We perform 21 cm cosmology due to its relation with reionization; by detecting this emission line, we can identify the timing of reionization, and understand more about the nature of the universe during the birth of the first stars and galaxies. With that, we can understand the heating conditions of the initial universe, providing us a larger picture of the conditions that created the large-scale structure of the universe we observe today. The HERA array currently consists of 19 antennas, spaced in a hexagonal grid pattern. We consider a robust observable, the time-averaged visibility (TAV), which is in principle sensitive to variations in the beam pattern between antenna elements and is easier to measure than the beam pattern itself. We use this TAV to explore the non-redundancy of baselines in the HERA array due either to cross-coupling between antennas (probed by antenna location in the array) or non-uniformity in their manufacture. The TAV may provide a simple way of verifying improvements in antenna element redundancy.

  17. Foil changing apparatus

    DOEpatents

    Crist, Charles E.; Ives, Harry C.; Leifeste, Gordon T.; Miller, Robert B.

    1988-01-01

    A self-contained hermetically sealed foil changer for advancing a portion of foil web into a position normal to the path of a high energy particle beam. The path of the beam is defined generally by an aperture plate and cooperating axially movable barrel such that the barrel can be advanced toward the plate thereby positioning a portion of the foil across the beam path and sealing the foil between the barrel and the plate to form a membrane across said beam path. A spooling apparatus contained in the foil changer permits selectively advancing a fresh supply of foil across the beam path without breaking the foil changer seal.

  18. A study of aging effects of barrel Time-Of-Flight system in the BESIII experiment

    NASA Astrophysics Data System (ADS)

    Liu, Huan-Huan; Sun, Sheng-Sen; Fang, Shuang-Shi; Wu, Zhi; Dai, Hong-Liang; Heng, Yue-Kun; Zhou, Ming; Deng, Zi-Yan; Liu, Huai-Min

    2018-02-01

    The Time-Of-Flight system consisting of plastic scintillation counters plays an important role for particle identification in the BESIII experiment at the BEPCII double ring e+e- collider. Degradation of the detection efficiency of the barrel TOF system has been observed since the start of physical data taking and this effect has triggered intensive and systematic studies about aging effects of the detector. The aging rates of the attenuation lengths and relative gains are obtained based on the data acquired in past several years. This study is essential for ensuring an extended operation of the barrel TOF system in optimal conditions.

  19. Mass sensitivity studies for an inductively driven railgun

    NASA Astrophysics Data System (ADS)

    Scanlon, J. J., III; Young, A. F.

    1991-01-01

    Those areas which result in substantial system mass reductions for an HPG (homopolar generator) driven EML (electromagnetic launcher) are identified. Sensitivity studies are performed by varying launch mass, peak acceleration, launcher efficiency, inductance gradient, injection velocity, barrel mass per unit length, fuel tankage and pump estimates, and component energy and power densities. Two major contributors to the system mass are the allowed number of shots per barrel versus the number required for the mission, and the barrel length. The effects of component performance parameters, such as friction coefficient, injection velocity, ablation coefficient, rail resistivity, armature voltage, peak acceleration, and inductance gradient on these two areas, are addressed.

  20. Dynamic changes of rodent somatosensory barrel cortex are correlated with learning a novel conditioned stimulus.

    PubMed

    Long, John D; Carmena, Jose M

    2013-05-01

    The rodent somatosensory barrel cortex (S1bf) has proved a valuable model for studying neural plasticity in vivo. It has been observed that sensory deprivation or conditioning reorganizes sensory-driven activity within S1bf. These observations suggest a role for S1bf in somatosensory learning. This study evaluated the hypothesis that the response properties of extracellularly recorded neurons in S1bf would change as subjects learned to respond to stimulation of S1bf. Intracortical microstimulation (ICMS) of S1bf was used as a means for bypassing feedforward drive from the sensory periphery, midbrain, and thalamus while exciting local cortical networks. To separate the learning of this conditioned stimulus-conditioned response (CS-CR) from other elements of the task, we employed a cross-modal transfer schedule. Long-Evans rats were initially trained to respond to an auditory stimulus. All subjects were then implanted in both S1bfs with chronic microwire arrays for recording neural activity and delivering ICMS. Next, this association was transferred to ICMS of one hemisphere's S1bf. S1bf responded to ICMS with a brief increase in firing rate followed by a longer reduction in activity. We observed that the duration of reduced activity elicited by ICMS increased as the subjects began to respond correctly more often than expected by chance, and the magnitude of the initial positive response increased as they consolidated this CS-CR. Subsequent ICMS of the opposite S1bf revealed that this CS-CR did not generalize across hemispheres. These results suggest that a mechanism involving a single hemisphere's S1bf tunes cortical responses in concert with changes in rodent behavior during somatosensory learning.

  1. Carbonic acid buffer species measured in real time with an intracellular microelectrode array

    PubMed Central

    Wietasch, Kristina; Kraig, Richard P.

    2009-01-01

    Carbonic acid buffer anions, HCO3−andCO32−, play an instrumental role in a host of vital processes in animal cells and tissues. Yet study of carbonic acid buffer species is hampered because no means are available to simultaneously monitor them at a cellular level in a rapid and dynamic fashion. An ion-selective cocktail, previously reported to measure changes in bicarbonate activity (αHCO3−), was instead shown to be principally selective for αCO32−. Ion-selective micropipettes (ISMs) based on this exchanger and consisting of a 3:1:6 (volume) mixture of tri-n-octylpropylammonium chloride, 1-octanol, and trifluoroacetyl-p-butylbenzene showed no significant interference from bicarbonate, chloride, phosphate, ascorbate, lactate, glutamate, acetate, or hydroxyl ions at concentrations expected in vivo. Intracellular and triple-barrel ISMs, consisting of a CO32−-sensitive, pH-sensitive, and reference barrel, were fabricated. Skeletal muscle cells (n = 17) were penetrated in vivo and showed values of 74 ± 7 mV for membrane potential, 6.94 ± 0.09 pHi, and 11 ± 5 µM intracellular αCO32−, from which intracellular αHCO3− of 25 ± 10 mM and CO2 tension of 120 ± 55 Torr were calculated. All ion measurements reached a new steady state in 9 ± 2 s after cell penetration. Thus measurements of intracellular αCO32− and pH and associated levels of αHCO3 and CO2 tension can be determined in biological tissues and cells with a spatial and temporal resolution previously unattainable. PMID:1653544

  2. Ultrabroadband Phased-Array Receivers Based on Optical Techniques

    DTIC Science & Technology

    2016-02-26

    AFRL-AFOSR-VA-TR-2016-0121 Ultrabroadband Phased- array Receivers Based on Optical Techniques Christopher Schuetz UNIVERSITY OF DELAWARE Final Report...Jul 15 4. TITLE AND SUBTITLE Ultrabroadband Phased- Array Receivers Based on Optical Techniques 5a. CONTRACT NUMBER 5b. GRANT NUMBER FA9550-12-1...receiver that enables us to capture and convert signals across an array using photonic modulators, routing these signals to a central location using

  3. 40 CFR 98.386 - Data reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Suppliers of Coal-based Liquid Fuels § 98.386 Data reporting... barrels. For natural gas liquids, quantity shall reflect the individual components of the product. (3) For... quantity in metric tons or barrels. For natural gas liquids, quantity shall reflect the individual...

  4. An oilspill risk analysis for the Gulf of Mexico outer continental shelf lease area; regional environmental impact statement

    USGS Publications Warehouse

    LaBelle, R.P.

    1982-01-01

    An oilspill risk analysis was conducted for the Gulf of Mexico Outer Continental Shelf (OCS)lease area region. Results of the analysis can be used to determine relative risks associated with oil production in different regions to be offered in OCS Lease Sales 72, 74, and 79. The analysis considered the probability of spill occurrences based on historical trends; likely movement of oil slicks based on a climatological model; and locations of major environmental resources which could be vulnerable to spilled oil. The times between spill occurrence and contact with resources were estimated to aid in estimating slick characteristics. Critical assumptions made for this particular analysis were (1) that oil exists in the lease area, and (2) that oil will be, found and produced from tracts sold in sales 72, 74, and 79. On the basis of a most likely resource estimate of 241 million barrels of oil to be produced over an 18-year production life from sales to be held in 1983 (sales 72, 74, 79), it was calculated that approximately one oilspill of 1,000 barrels or larger will occur. The estimated probability that one or more oilspills of 1,000 barrels or larger will occur and contact land after being at sea less than 30 days is 41-percent. For a high resource estimate case of sales to be held in 1983, 717 million barrels are estimated to be produced over an 18-year production life with an 83-percent chance of one or more spills of 1,000 barrels or larger occurring and contacting land within 30 days. These results depend upon the routes and methods chosen to transport oil from OCS platforms to shore. Given a total development scenario in which 5.6 billion barrels of oil are estimated to be present and produced, it was calculated that 18 oilspills of 1,000 barrels or larger will occur over the 40-year production life of the proposed lease area. The estimated probability that one or more oilspills of 1,000 barrels or larger will occur and contact land after being at sea less than 30 days is greater than 99.5 percent for this scenario. These probabilities also reflect the assumptions that oilspills remain intact for up to 30 days, do not weather, and are not cleaned up. It should be noted that the expected number of spills from the total development scenario is less than one-half that of the expected number from existing tanker transportation of crude oil imports in the Gulf area.

  5. The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel.

    PubMed

    Freinkman, Elizaveta; Chng, Shu-Sin; Kahne, Daniel

    2011-02-08

    The cell surfaces of Gram-negative bacteria are composed of lipopolysaccharide (LPS). This glycolipid is found exclusively in the outer leaflet of the asymmetric outer membrane (OM), where it forms a barrier to the entry of toxic hydrophobic molecules into the cell. LPS typically contains six fatty acyl chains and up to several hundred sugar residues. It is biosynthesized in the cytosol and must then be transported across two membranes and an aqueous intermembrane space to the cell surface. These processes are required for the viability of most Gram-negative organisms. The integral membrane β-barrel LptD and the lipoprotein LptE form an essential complex in the OM, which is necessary for LPS assembly. It is not known how this complex translocates large, amphipathic LPS molecules across the OM to the outer leaflet. Here, we show that LptE resides within the LptD β-barrel both in vitro and in vivo. LptD/E associate via an extensive interface; in one specific interaction, LptE contacts a predicted extracellular loop of LptD through the lumen of the β-barrel. Disrupting this interaction site compromises the biogenesis of LptD. This unprecedented two-protein plug-and-barrel architecture suggests how LptD/E can insert LPS from the periplasm directly into the outer leaflet of the OM to establish the asymmetry of the bilayer.

  6. Metal dust deposition in a shotgun wound associated with barrel modification.

    PubMed

    Williams, Andrew S; Bowes, Matthew J

    2016-03-01

    Contact-range gunshot wounds commonly demonstrate deposition of black soot in and around the wound. Deposition of other visible pigments originating from the firearm has not been specifically described. In the current case, an adult male was found dead adjacent to a shotgun fixed in a vice grip with a modified, shortened barrel. A handheld, powered, metal grinding wheel was nearby. Autopsy revealed an intraoral gunshot wound, including soot deposition in and around the mouth and within the wound track. In addition, there was a peculiar, gray, lustrous film on the lips, gingiva, and anterior teeth. The material was concentrated around the most severe areas of injury in the anterior mouth and easily rubbed off with a cotton swab. It was not visualized in the rest of the mouth and not present in the larynx, or the esophagus. Overall, our opinion is that this unique, gray, lustrous film represents deposition of fine metallic dust that accumulated in the barrel of the shotgun during its modification with the grinding wheel. This type of unique pigment deposition should be recognized by forensic pathologists as possibly being related to the discharge of a firearm with a recently modified barrel or other cause for fine metallic dust accumulation within the barrel. Depending on the circumstances of the case, collection of samples of such metal dust deposits could be indicated for subsequent analysis.

  7. Coevolving residues of (beta/alpha)(8)-barrel proteins play roles in stabilizing active site architecture and coordinating protein dynamics.

    PubMed

    Shen, Hongbo; Xu, Feng; Hu, Hairong; Wang, Feifei; Wu, Qi; Huang, Qiang; Wang, Honghai

    2008-12-01

    Indole-3-glycerol phosphate synthase (IGPS) is a representative of (beta/alpha)(8)-barrel proteins-the most common enzyme fold in nature. To better understand how the constituent amino-acids work together to define the structure and to facilitate the function, we investigated the evolutionary and dynamical coupling of IGPS residues by combining statistical coupling analysis (SCA) and molecular dynamics (MD) simulations. The coevolving residues identified by the SCA were found to form a network which encloses the active site completely. The MD simulations showed that these coevolving residues are involved in the correlated and anti-correlated motions. The correlated residues are within van der Waals contact and appear to maintain the active site architecture; the anti-correlated residues are mainly distributed on opposite sides of the catalytic cavity and coordinate the motions likely required for the substrate entry and product release. Our findings might have broad implications for proteins with the highly conserved (betaalpha)(8)-barrel in assessing the roles of amino-acids that are moderately conserved and not directly involved in the active site of the (beta/alpha)(8)-barrel. The results of this study could also provide useful information for further exploring the specific residue motions for the catalysis and protein design based on the (beta/alpha)(8)-barrel scaffold.

  8. Demonstrating the effect of forensic firearm countermeasures: Bullet characteristics generated due to barrel modifications.

    PubMed

    O'Keeffe, C; Champion, S; Allsop, D

    2015-12-01

    Forensic awareness and the declining availability of firearms have resulted in an increase in the use of modified and re-activated firearms in crime. Although some modifications are undertaken to simply acquire a functioning firearm, others are perpetrated as a direct forensic countermeasure to prevent the association between a firearm and a crime. This article describes the effects of these modifications on bullet striation patterns imparted from the barrel to a fired bullet. The key results indicated that the investigated modifications display assessable characteristics. The use of an oversized barrel imparted striations consistent with firing with the absence of typical rifling. Subsequent or consecutively fired bullets possessed striation variations, with the first showing the least evidence of striations. The application of a choke resulted in more obvious bullet elongation compared to a smoothbore barrel. The restriction caused merging of lands and groves of the imparted rifling and obscured their usual definition. Effects of breech adaption were also characterised by observing the buckling and enlargement of the cartridge case. This deformity of the cartridge case was most evident when the barrel pressure increased due to the presence of the choke. From this study it was evident that unique characteristic impressions associated with different modifications most commonly found in criminal investigations can be utilised by a forensic expert and impart significant intelligence to an investigation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. High precision optomechanical assembly using threads as mechanical reference

    NASA Astrophysics Data System (ADS)

    Lamontagne, Frédéric; Desnoyers, Nichola; Bergeron, Guy; Cantin, Mario

    2016-09-01

    A convenient method to assemble optomechanical components is to use threaded interface. For example, lenses are often secured inside barrels using threaded rings. In other cases, multiple optical sub-assemblies such as lens barrels can be threaded to each other. Threads have the advantage to provide a simple assembly method, to be easy to manufacture, and to offer a compact mechanical design. On the other hand, threads are not considered to provide accurate centering between parts because of the assembly clearance between the inner and outer threads. For that reason, threads are often used in conjunction with precision cylindrical surfaces to limit the radial clearance between the parts to be centered. Therefore, tight manufacturing tolerances are needed on these pilot diameters, which affect the cost of the optical assembly. This paper presents a new optomechanical approach that uses threads as mechanical reference. This innovative method relies on geometric principles to auto-center parts to each other with a very low centering error that is usually less than 5 μm. The method allows to auto-center an optical group in a main barrel, to perform an axial adjustment of an optical group inside a main barrel, and to perform stacking of multiple barrels. In conjunction with the lens auto-centering method that also used threads as a mechanical reference, this novel solution opens new possibilities to realize a variety of different high precision optomechanical assemblies at lower cost.

  10. Learning-Dependent Plasticity of the Barrel Cortex Is Impaired by Restricting GABA-Ergic Transmission.

    PubMed

    Posluszny, Anna; Liguz-Lecznar, Monika; Turzynska, Danuta; Zakrzewska, Renata; Bielecki, Maksymilian; Kossut, Malgorzata

    2015-01-01

    Experience-induced plastic changes in the cerebral cortex are accompanied by alterations in excitatory and inhibitory transmission. Increased excitatory drive, necessary for plasticity, precedes the occurrence of plastic change, while decreased inhibitory signaling often facilitates plasticity. However, an increase of inhibitory interactions was noted in some instances of experience-dependent changes. We previously reported an increase in the number of inhibitory markers in the barrel cortex of mice after fear conditioning engaging vibrissae, observed concurrently with enlargement of the cortical representational area of the row of vibrissae receiving conditioned stimulus (CS). We also observed that an increase of GABA level accompanied the conditioning. Here, to find whether unaltered GABAergic signaling is necessary for learning-dependent rewiring in the murine barrel cortex, we locally decreased GABA production in the barrel cortex or reduced transmission through GABAA receptors (GABAARs) at the time of the conditioning. Injections of 3-mercaptopropionic acid (3-MPA), an inhibitor of glutamic acid decarboxylase (GAD), into the barrel cortex prevented learning-induced enlargement of the conditioned vibrissae representation. A similar effect was observed after injection of gabazine, an antagonist of GABAARs. At the behavioral level, consistent conditioned response (cessation of head movements in response to CS) was impaired. These results show that appropriate functioning of the GABAergic system is required for both manifestation of functional cortical representation plasticity and for the development of a conditioned response.

  11. Superconducting Detectors for Study of Infant Universe

    NASA Image and Video Library

    2014-03-17

    The BICEP2 telescope at the South Pole used a specialized array of superconducting detectors to capture polarized light from billions of years ago. The detector array is shown here, under a microscope.

  12. Assessment of Undiscovered Oil and Gas Resources of the Nile Delta Basin Province, Eastern Mediterranean

    USGS Publications Warehouse

    Kirschbaum, Mark A.; Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Brownfield, Michael E.; Pitman, Janet K.; Cook, Troy A.; Tennyson, Marilyn E.

    2010-01-01

    The U.S. Geological Survey estimated means of 1.8 billion barrels of recoverable oil, 223 trillion cubic feet of recoverable gas, and 6 billion barrels of natural gas liquids in the Nile Delta Basin Province using a geology-based assessment methodology.

  13. 27 CFR 25.144 - Rebranding barrels and kegs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Marks, Brands, and Labels § 25.144 Rebranding barrels and... permanently remove or durably cover the original marks and brands after notifying the appropriate TTB officer... the original marks and brands if the brewer: (1) Adopts a trade name substantially identical to the...

  14. Computed tomography manifestation of a triple-barreled aortic dissection: the Mercedes-Benz mark sign.

    PubMed

    Shin, M S; Zorn, G L; Ho, K J

    1988-04-01

    Computed tomographic (CT) findings of a rare case of triple-barreled aortic dissection was described. CT demonstrated the extent of dissection, a communication between two channels, and three lumens separated by the intimal flap and a thin undetached tunica media, resembling a Mercedes-Benz mark.

  15. VARIABLES AFFECTING EMISSIONS OF PCDDS/FS FROM UNCONTROLLED COMBUSTION OF HOUSEHOLD WASTE IN BARRELS

    EPA Science Inventory

    The uncontrolled burning of household waste in barrels has recently been implicated as a major source of airborne emissions of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDDs/Fs). Based on the need to generate a more accurate emission factor for burn ba...

  16. PARAMETERS INFLUENCING EMISSIONS OF PCDDS/FS FROM OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS

    EPA Science Inventory

    The paper reports results from tests that were designed to examine some of the factors influencing the emissions of polychlorinated-p-dioxins and polychlorinated dibenzofurans (PCDDs/Fs) from burn barrels. Based on the wide variability of emissions within duplicate-run sets, in ...

  17. 11. DETAIL, ARCH BARREL AND RING, FROM SOUTHWEST, SHOWING CUT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. DETAIL, ARCH BARREL AND RING, FROM SOUTHWEST, SHOWING CUT STONE MASONRY RINGSTONE VOUSSOIRS WITH '1902' KEYSTONE, CONCRETE PARAPET, CONCRETE APRON AT BASE OF BRIDGE UNDER ARCH, AND PORTION OF TIMBER GRILLAGE - Boston Street Bridge, Spanning Harris Creek Sewer at Boston Street, Baltimore, Independent City, MD

  18. 27 CFR 478.28 - Transportation of destructive devices and certain firearms.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... destructive devices and certain firearms. 478.28 Section 478.28 Alcohol, Tobacco Products, and Firearms BUREAU... destructive devices and certain firearms. (a) The Director may authorize a person to transport in interstate or foreign commerce any destructive device, machine gun, short-barreled shotgun, or short-barreled...

  19. PHYSICAL VAPOR DEPOSITION OF TANTALUM ON GUN BARREL STEEL (SYSTEMS ANLAYSIS BRANCH, SUSTAINABLE TECHNOLOGY DIVISION, NRMRL)

    EPA Science Inventory

    This project entails the development of an alternative technology for plating gun barrel steel to replace the process electroplating of chrome (Cr-electroplate) with physical vapor deposition of tantalum (Ta-PVD). Developed by Benet Laboratory at Watervliet Arsenal, this project'...

  20. Rain Barrels: A Catalyst for Change?

    ERIC Educational Resources Information Center

    Bakacs, Michele E.; Haberland, Mike; Mangiafico, Salvatore S.; Winquist, Aileen; Obropta, Christopher C.; Boyajian, Amy; Mellor, Sara

    2013-01-01

    Over the past 4 years, rain barrel programming for residents has been implemented in both Northern Virginia and New Jersey as a method for educating the public about stormwater management and water conservation. Program participants demonstrated a significant increase in knowledge of water resource issues. Follow-up surveys showed 58% of New…

  1. EMISSIONS OF POLYCHLORINATED DIBENZO-P-DIOXINS AND POLYCHLORINATED DIBENZOFURANS FROM THE OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS

    EPA Science Inventory

    Backyard burning of household waste in barrels is a common waste disposal practice for which pollutant emissions have not been well characterized. This study measured the emissions of several pollutants, including polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofura...

  2. 8. Generator Barrel and Shaft of Unit 1, view to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Generator Barrel and Shaft of Unit 1, view to the northwest, with turbine shaft and thrust bearing visible in upper center of photograph. - Washington Water Power Clark Fork River Noxon Rapids Hydroelectric Development, Powerhouse, South bank of Clark Fork River at Noxon Rapids, Noxon, Sanders County, MT

  3. Assessment of undiscovered oil and gas resources of Libya and Tunisia, 2010

    USGS Publications Warehouse

    Whidden, Katherine J.; Lewan, Michael; Schenk, Christopher J.; Charpentier, Rondald R.; Cook, Troy A.; Klett, Timothy R.; Pitman, Janet K.

    2011-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 3.97 billion barrels of undiscovered oil, 38.5 trillion cubic feet of undiscovered natural gas, and 1.47 billion barrels of undiscovered natural gas liquids in two provinces of North Africa.

  4. EVALUATION OF EMISSIONS FROM THE OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS - VOLUME 1. TECHNICAL REPORT

    EPA Science Inventory

    The report gives results of a detailed emissions characterization study undertaken to examine, characterize, and quantify emissions from the simulated burning of household waste in barrels. The study evaluated two waste streams: that of an avid recycler, who removed most of the r...

  5. EVALUATION OF EMISSIONS FROM THE OPEN BURNING OF HOUSEHOLD WASTES IN BARRELS - VOLUME 2. APPENDICES

    EPA Science Inventory

    The report gives results of a detailed emissions characterization study undertaken to examine, characterize, and quantify emissions from the simulated burning of household waste in barrels. The study evaluated two waste streams: that of an avid recycler, who removed most of the r...

  6. Optical Path Difference Fluctations at the CHARA Interferometric Array

    NASA Astrophysics Data System (ADS)

    Merand, A.; ten Brummelaar, T. A.; McAlister, H. A.; Ridgway, S. T.; Sturmann, J.; Sturmann, L.; Turner, N. H.; Bagnuolo, W. G.; Hrynevych, M.; Shure, M. A.

    2001-05-01

    Commissioning observations at the CHARA Array have been carried out with the two south telescopes, with a telescope separation of 34 meters. Due to the size of the array (>340 meters across) and the optical delay geometry, the beams travel horizontal distances of approximately 200 meters, with a number of reflections in the telescope coude area and the optical delay and beam combination areas. Stellar and laboratory observations have been analyzed to determine the variations of the optical path, as revealed by shifts in the interference pattern. The power spectra of the OPD variations are diagnostic of the atmospheric turbulence characteristics, and of any internal vibrations in the laboratory. Results of the OPD analysis will be compared to similar studies at other interferometric facilities. The CHARA Array, a six-telescope O/IR interferometric array operated by Georgia State University on Mt. Wilson, Calfornia, was funded by the National Science Foundation, the W.M. Keck Foundation, the David and Lucile Packard Foundation, and Georgia State University.

  7. Signal Processing for a Lunar Array: Minimizing Power Consumption

    NASA Technical Reports Server (NTRS)

    D'Addario, Larry; Simmons, Samuel

    2011-01-01

    Motivation for the study is: (1) Lunar Radio Array for low frequency, high redshift Dark Ages/Epoch of Reionization observations (z =6-50, f=30-200 MHz) (2) High precision cosmological measurements of 21 cm H I line fluctuations (3) Probe universe before first star formation and provide information about the Intergalactic Medium and evolution of large scale structures (5) Does the current cosmological model accurately describe the Universe before reionization? Lunar Radio Array is for (1) Radio interferometer based on the far side of the moon (1a) Necessary for precision measurements, (1b) Shielding from earth-based and solar RFI (12) No permanent ionosphere, (2) Minimum collecting area of approximately 1 square km and brightness sensitivity 10 mK (3)Several technologies must be developed before deployment The power needed to process signals from a large array of nonsteerable elements is not prohibitive, even for the Moon, and even in current technology. Two different concepts have been proposed: (1) Dark Ages Radio Interferometer (DALI) (2)( Lunar Array for Radio Cosmology (LARC)

  8. 16-element photodiode array for the angular microdeflection detector and for stabilization of a laser radiation direction

    NASA Astrophysics Data System (ADS)

    Wegrzecki, Maciej; Piotrowski, Tadeusz; Bar, Jan; Dobrowolski, Rafał; Klimov, Andrii; Klos, Helena; Marchewka, Michał; Nieprzecki, Marek; Panas, Andrzej; Prokaryn, Piotr; Seredyński, Bartłomiej; Sierakowski, Andrzej; Słysz, Wojciech; Szmigiel, Dariusz; Zaborowski, Michal

    2016-12-01

    In this paper, the design and technology of two types of 16-element photodiode arrays is described. The arrays were developed by the ITE and are to be used in detection of microdeflection of laser radiation at the Institute of Metrology and Biomedical Engineering in the Faculty of Mechatronics of Warsaw University of Technology. The electrical and photoelectrical parameters of the arrays are presented.

  9. Firearm equipped with live round inhibiting means and method of making same

    DOEpatents

    Baehr, D.G.

    1990-11-13

    A firearm is disclosed having live round inhibiting means mounted in the barrel of the firearm which permits a blank cartridge to be loaded into a firearm and fired while preventing the loading and firing of a live round. The live round inhibiting means comprise shaft means mounted in the barrel of the firearm and which extends a sufficient length into the barrel at a point just beyond the chamber portion of the firearm to engage the bullet portion of a live round to prevent it from properly chambering, while permitting a blank cartridge to be loaded into the firearm and fired without engaging the live round-inhibiting shaft means. 9 figs.

  10. The worldwide search for petroleum offshore; a status report for the quarter century, 1947-72

    USGS Publications Warehouse

    Berryhill, Henry L.

    1974-01-01

    At the end of 1972, offshore petroleum exploration was in progress on the submerged continental margins of 80 countries. Some 780 oil and gas fields had been discovered. Estimated worldwide volume of oil discovered offshore as of January 1, 1973, is 172.8 billion barrels of oil, or about 26 percent of the world total, and 168.4 trillion ft3 of natural gas. Present reserves of oil are 135.5 billion barrels, of which 70 percent is in the Persian Gulf. Some 90 percent of the oil discovered offshore has been found in 60 giant fields having reserves of 500 million or more barrels each.

  11. Firearm equipped with live round inhibiting means and method of making same

    DOEpatents

    Baehr, Donald G.

    1990-01-01

    A firearm is disclosed having live round inhibiting means mounted in the barrel of the firearm which permits a blank cartridge to be loaded into a firearm and fired while preventing the loading and firing of a live round. The live round inhibiting means comprise shaft means mounted in the barrel of the firearm and which extends a sufficient length into the barrel at a point just beyond the chamber portion of the firearm to engage the bullet portion of a live round to prevent it from properly chambering, while permitting a blank cartridge to be loaded into the firearm and fired without engaging the live round-inhibiting shaft means.

  12. Parallel integer sorting with medium and fine-scale parallelism

    NASA Technical Reports Server (NTRS)

    Dagum, Leonardo

    1993-01-01

    Two new parallel integer sorting algorithms, queue-sort and barrel-sort, are presented and analyzed in detail. These algorithms do not have optimal parallel complexity, yet they show very good performance in practice. Queue-sort designed for fine-scale parallel architectures which allow the queueing of multiple messages to the same destination. Barrel-sort is designed for medium-scale parallel architectures with a high message passing overhead. The performance results from the implementation of queue-sort on a Connection Machine CM-2 and barrel-sort on a 128 processor iPSC/860 are given. The two implementations are found to be comparable in performance but not as good as a fully vectorized bucket sort on the Cray YMP.

  13. Barrel calorimeter of the CMD-3 detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shebalin, V. E., E-mail: V.E.Shebalin@inp.nsk.su; Anisenkov, A. V.; Aulchenko, V. M.

    The structure of the barrel calorimeter of the CMD-3 detector is presented in this work. The procedure of energy calibration of the calorimeter and the method of photon energy restoration are described. The distinctive feature of this barrel calorimeter is its combined structure; it is composed of two coaxial subsystems: a liquid xenon calorimeter and a crystalline CsI calorimeter. The calorimeter spatial resolution of the photon conversion point is about 2 mm, which corresponds to an angular resolution of ∼6 mrad. The energy resolution of the calorimeter is about 8% for photons with energy of 200 MeV and 4% formore » photons with energy of 1 GeV.« less

  14. U.S. Geological Survey assessment of reserve growth outside of the United States

    USGS Publications Warehouse

    Klett, Timothy R.; Cook, Troy A.; Charpentier, Ronald R.; Tennyson, Marilyn E.; Le, Phuong A.

    2015-12-21

    The U.S. Geological Survey estimated volumes of technically recoverable, conventional petroleum resources resulting from reserve growth for discovered fields outside the United States that have reported in-place oil and gas volumes of 500 million barrels of oil equivalent or greater. The mean volumes of reserve growth were estimated at 665 billion barrels of crude oil; 1,429 trillion cubic feet of natural gas; and 16 billion barrels of natural gas liquids. These volumes constitute a significant portion of the world’s oil and gas resources and represent the potential future growth of current global reserves over time based on better assessment methodology, new technologies, and greater understanding of reservoirs.

  15. 76 FR 46668 - Revision to Form No. 6

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ...] Revision to Form No. 6 AGENCY: Federal Energy Regulatory Commission. ACTION: Notice of proposed rulemaking... 700 of FERC Form No. 6 (Form 6) to ensure that pipelines report interstate-only barrel and barrel-mile... 700 of their 2010 Form 6 to file a revised page 700 containing only interstate data for the years 2009...

  16. Assessment of undiscovered oil and gas resources of the Paris Basin, France, 2015

    USGS Publications Warehouse

    Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Tennyson, Marilyn E.; Mercier, Tracey J.; Le, Phoung A.; Brownfield, Michael E.; Pitman, Janet K.; Gaswirth, Stephanie B.; Marra, Kristen R.; Leathers, Heidi M.

    2015-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 222 million barrels of unconventional oil; 2,092 billion cubic feet of unconventional gas; 18 million barrels of conventional oil; and 47 billion cubic feet of conventional gas resources in the Paris Basin of France.

  17. 27 CFR 479.93 - Transfers of firearms to certain persons.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... persons. Where the transfer of a destructive device, machine gun, short-barreled shotgun, or short-barreled rifle is to be made by a person licensed under the provisions of Title I of the Gun Control Act of...

  18. 27 CFR 479.93 - Transfers of firearms to certain persons.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... persons. Where the transfer of a destructive device, machine gun, short-barreled shotgun, or short-barreled rifle is to be made by a person licensed under the provisions of Title I of the Gun Control Act of...

  19. 27 CFR 479.93 - Transfers of firearms to certain persons.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... persons. Where the transfer of a destructive device, machine gun, short-barreled shotgun, or short-barreled rifle is to be made by a person licensed under the provisions of Title I of the Gun Control Act of...

  20. 27 CFR 479.93 - Transfers of firearms to certain persons.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... persons. Where the transfer of a destructive device, machine gun, short-barreled shotgun, or short-barreled rifle is to be made by a person licensed under the provisions of Title I of the Gun Control Act of...

  1. 27 CFR 479.93 - Transfers of firearms to certain persons.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... persons. Where the transfer of a destructive device, machine gun, short-barreled shotgun, or short-barreled rifle is to be made by a person licensed under the provisions of Title I of the Gun Control Act of...

  2. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Conveyor for moving and draining block or barrel cheese. 58.425 Section 58.425 Agriculture Regulations of the Department of Agriculture (Continued... cheese. The conveyor shall be constructed so that it will not contaminate the cheese and be easily...

  3. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Conveyor for moving and draining block or barrel cheese. 58.425 Section 58.425 Agriculture Regulations of the Department of Agriculture (Continued... cheese. The conveyor shall be constructed so that it will not contaminate the cheese and be easily...

  4. Exercise-induced pulmonary hemorrhage in barrel racing horses in the Pacific Northwest region of the United States

    USDA-ARS?s Scientific Manuscript database

    Background: Exercise-induced pulmonary hemorrhage (EIPH) refers to bleeding from the lungs in association with strenuous exercise. It has been documented in race horses but little information exists on EIPH in barrel racing horses. Hypothesis/Objectives: Our goals were to evaluate the presence of EI...

  5. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  6. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  7. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  8. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  9. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  10. 78 FR 71989 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... forward engine mount, and related investigative and corrective actions if necessary. This AD was prompted by a report of cracked barrel nuts found on a forward engine mount. We are issuing this AD to detect and correct cracked barrel nuts on a forward engine mount, which could result in reduced load capacity...

  11. Assessment of unconventional oil and gas resources in Northeast Mexico, 2014

    USGS Publications Warehouse

    Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Tennyson, Marilyn E.; Gaswirth, Stephanie B.; Brownfield, Michael E.; Pawlewicz, Mark J.; Weaver, Jean Noe

    2014-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 0.78 billion barrels of unconventional oil, 23.5 trillion cubic feet of unconventional gas, and 0.88 billion barrels of natural gas liquids in the Sabinas Basin, Burgos Basin, and Tampico-Misantla Basin provinces of northeast Mexico.

  12. Assessment of undiscovered conventional oil and gas resources of six geologic provinces of China

    USGS Publications Warehouse

    Charpentier, Ronald R.; Schenk, Christopher J.; Brownfield, Michael E.; Cook, Troy A.; Klett, Timothy R.; Pitman, Janet K.; Pollastro, Richard M.

    2012-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated mean volumes of undiscovered conventional petroleum resources in six geologic provinces of China at 14.9 billion barrels of oil, 87.6 trillion cubic feet of natural gas, and 1.4 billion barrels of natural-gas liquids.

  13. Postnatal Development of CB1 Receptor Expression in Rodent Somatosensory Cortex

    PubMed Central

    Deshmukh, Suvarna; Onozuka, Kaori; Bender, Kevin J.; Bender, Vanessa A.; Lutz, Beat; Mackie, Ken; Feldman, Daniel E.

    2007-01-01

    Endocannabinoids are powerful modulators of synaptic transmission that act on presynaptic cannabinoid receptors. Cannabinoid receptor type 1 (CB1) is the dominant receptor in the CNS, and is present in many brain regions, including sensory cortex. To investigate the potential role of CB1 receptors in cortical development, we examined the developmental expression of CB1 in rodent primary somatosensory (barrel) cortex, using immunohistochemistry with a CB1-specific antibody. We found that before postnatal day (P) 6, CB1 receptor staining was present exclusively in the cortical white matter, and that CB1 staining appeared in the grey matter between P6 and P20 in a specific laminar pattern. CB1 staining was confined to axons, and was most prominent in cortical layers 2/3, 5a, and 6. CB1 null (−/−) mice showed altered anatomical barrel maps in layer 4, with enlarged inter-barrel septa, but normal barrel size. These results indicate that CB1 receptors are present in early postnatal development and influence development of sensory maps. PMID:17210229

  14. Total Maxillary Reconstruction With a Bi-Paddle Double-Barrel Osteocutaneous Fibular Flap and Arteriovenous Saphenous Loop After a Globe-Sparing Total Maxillectomy Due to Osteosarcoma.

    PubMed

    Tseng, Wan-Ling; Chang, Tzu-Yen; Hung, Kuo-Shu; Chen, Szu-Han; Hsiao, Jenn-Ren; Lee, Yao-Chou

    2017-01-01

    The titanium mesh or bone graft is usually used for orbital support after a globe-sparing total maxillectomy. However, its use can invite complications, such as infection, exposure, and absorption, especially for patients who require adjuvant radiotherapy. Here, the authors present a patient who received total maxillary reconstruction with an osteocutaneous fibular flap. A 53-year-old man with the diagnosis of maxillary osteosarcoma received a globe-sparing total maxillectomy. A bi-paddle double-barrel osteocutaneous fibular flap was used for orbital support, alveolar ridge recreation, and oro-sino-nasal separation. The short pedicle length inherent in the double-barrel design of the fibular flap was overcome by creating an arteriovenous saphenous loop. The postoperative recovery was uneventful. During the 9 months follow-up, the patient was tumor-free and satisfied with his appearance, speech, and intake functions. Reconstruction with a bi-paddle double-barrel osteocutaneous fibular flap after a globe-sparing total maxillectomy can achieve satisfactory aesthetic and functional results.

  15. Frame for a firearm

    DOEpatents

    Crandall, David L [Idaho Falls, ID; Watson, Richard W [Blackfoot, ID

    2008-03-04

    A firearm frame which is adapted to be disposed in operative relationship as a component part of a firearm, the firearm having disposed in operative relationships each with one or more of the others, a barrel, a receiver, and at least one firing mechanism; wherein the barrel and receiver form operative parts of a movable assembly and the at least one firing mechanism is disposed in a substantially stationary operative relationship therewith; the firearm frame including at least one elongated support structure discrete from the barrel and receiver, the elongated support structure being adapted to directly support the movable assembly in an operative movable relationship therewith; whereby at least one of the barrel and receiver is in direct contact with and movable on the elongated support structure; and, a firing mechanism support structure connected to the at least one elongated support structure, the firing mechanism support structure being adapted to have the firing mechanism connected thereto; the firearm frame also directly supporting the movable assembly and the firing mechanism in corresponding movable and stationary operative relationships each with the other.

  16. A sampler for coring sediments in rivers and estuaries

    USGS Publications Warehouse

    Prych, Edmund A.; Hubbell, D.W.

    1966-01-01

    A portable sampler developed to core submerged unconsolidated sediments collects cores that are 180 cm long and 4.75cm in diameter. The sampler is used from a 12-m boat in water depths up to 20 m and in flow velocities up to 1.5m per second to sample river and estuarine deposits ranging from silty clay to medium sand. Even in sand that cannot be penetrated with conventional corers, the sampler achieves easy penetration through the combined application of vibration, suction, and axial force. A piston in the core barrel creates suction, and the suspension system is arranged so that tension on the support cable produces both a downward force on the core barrel and a lateral support against overturning. Samples are usually retained because of slight compaction in the driving head; as a precaution, however, the bottom of the core barrel is covered by a plate that closes after the barrel is withdrawn from the bed. Tests show that sample-retainers placed within the driving head restrict penetration and limit core lengths. Stratification within cores is disrupted little as a result of the sampling process.

  17. Structured networks support sparse traveling waves in rodent somatosensory cortex.

    PubMed

    Moldakarimov, Samat; Bazhenov, Maxim; Feldman, Daniel E; Sejnowski, Terrence J

    2018-05-15

    Neurons responding to different whiskers are spatially intermixed in the superficial layer 2/3 (L2/3) of the rodent barrel cortex, where a single whisker deflection activates a sparse, distributed neuronal population that spans multiple cortical columns. How the superficial layer of the rodent barrel cortex is organized to support such distributed sensory representations is not clear. In a computer model, we tested the hypothesis that sensory representations in L2/3 of the rodent barrel cortex are formed by activity propagation horizontally within L2/3 from a site of initial activation. The model explained the observed properties of L2/3 neurons, including the low average response probability in the majority of responding L2/3 neurons, and the existence of a small subset of reliably responding L2/3 neurons. Sparsely propagating traveling waves similar to those observed in L2/3 of the rodent barrel cortex occurred in the model only when a subnetwork of strongly connected neurons was immersed in a much larger network of weakly connected neurons.

  18. Visible light emission measurements from a dense electrothermal launcher plasma

    NASA Astrophysics Data System (ADS)

    Hankins, O. E.; Bourham, M. A.; Earnhart, J.; Gilligan, J. G.

    1993-01-01

    Measurements of the visible light emission from dense, weakly non-ideal plasmas have been performed on the experimental electrothermal launcher device 'SIRENS'. The plasma is created by the ablation or a Lexan insulator in the source, which then flows through a cylindrical barrel which serves as the material sample. Visible light emission spectra have been observed both in-bore and from the muzzle flash or the barrel, and from the flash or the source. Due to high plasma opacity (the plasma emits as a near blackbody) and absorption by the molecular components of the vapor shield, the hotter core or the arc has been difficult to observe. Recent measurements along the axis or the device indicate time-averaged plasma temperatures in the barrel or about 1 eV for lower energy shots, which agree with experimental measurements of the average heat flux and plasma conductivity along the barrel. Measurements or visible emission from the source indicate time averaged temperatures of 1 to 2 eV which agree with the theoretical estimates derived from ablated mass measurements and calculated estimates derived from plasma conductivity measurements.

  19. CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin

    PubMed Central

    van Pee, Katharina; Neuhaus, Alexander; D'Imprima, Edoardo; Mills, Deryck J; Kühlbrandt, Werner; Yildiz, Özkan

    2017-01-01

    Many pathogenic bacteria produce pore-forming toxins to attack and kill human cells. We have determined the 4.5 Å structure of the ~2.2 MDa pore complex of pneumolysin, the main virulence factor of Streptococcus pneumoniae, by cryoEM. The pneumolysin pore is a 400 Å ring of 42 membrane-inserted monomers. Domain 3 of the soluble toxin refolds into two ~85 Å β-hairpins that traverse the lipid bilayer and assemble into a 168-strand β-barrel. The pore complex is stabilized by salt bridges between β-hairpins of adjacent subunits and an internal α-barrel. The apolar outer barrel surface with large sidechains is immersed in the lipid bilayer, while the inner barrel surface is highly charged. Comparison of the cryoEM pore complex to the prepore structure obtained by electron cryo-tomography and the x-ray structure of the soluble form reveals the detailed mechanisms by which the toxin monomers insert into the lipid bilayer to perforate the target membrane. DOI: http://dx.doi.org/10.7554/eLife.23644.001 PMID:28323617

  20. Blank fire configuration for automatic pistol

    DOEpatents

    Teague, Tommy L.

    1990-01-01

    A pistol configured to fire blank cartridges includes a modified barrel with a breech portion connected to an aligned inner sleeve. Around the inner sleeve, there is disposed an outer sleeve having a vent therein through which the cartridge discharges. The breech portion is connected to a barrel anchor to move backward in a slight arc when the pistol is fired. A spring retention rod projects from the barrel anchor and receives a shortened recoil spring therearound which recoil spring has one end abutting a stop on the barrel anchor and the other end in abutment with the end of a spring retaining cup. The spring retaining cup is engaged by a flange projecting from a slide so that when the pistol is fired, the slide moves rearwardly against the compression of the spring to eject the spent cartridge and then moves forwardly under the urging of the spring to load a fresh cartridge into the breech portion. The spring then returns all of the slidable elements to their initial position so that the pistol may again be fired.

  1. An Evolutionarily Structured Universe of Protein Architecture

    PubMed Central

    Caetano-Anollés, Gustavo; Caetano-Anollés, Derek

    2003-01-01

    Protein structural diversity encompasses a finite set of architectural designs. Embedded in these topologies are evolutionary histories that we here uncover using cladistic principles and measurements of protein-fold usage and sharing. The reconstructed phylogenies are inherently rooted and depict histories of protein and proteome diversification. Proteome phylogenies showed two monophyletic sister-groups delimiting Bacteria and Archaea, and a topology rooted in Eucarya. This suggests three dramatic evolutionary events and a common ancestor with a eukaryotic-like, gene-rich, and relatively modern organization. Conversely, a general phylogeny of protein architectures showed that structural classes of globular proteins appeared early in evolution and in defined order, the α/β class being the first. Although most ancestral folds shared a common architecture of barrels or interleaved β-sheets and α-helices, many were clearly derived, such as polyhedral folds in the all-α class and β-sandwiches, β-propellers, and β-prisms in all-β proteins. We also describe transformation pathways of architectures that are prevalently used in nature. For example, β-barrels with increased curl and stagger were favored evolutionary outcomes in the all-β class. Interestingly, we found cases where structural change followed the α-to-β tendency uncovered in the tree of architectures. Lastly, we traced the total number of enzymatic functions associated with folds in the trees and show that there is a general link between structure and enzymatic function. PMID:12840035

  2. The oligomeric architecture of the archaeal exosome is important for processive and efficient RNA degradation.

    PubMed

    Audin, Maxime J C; Wurm, Jan Philip; Cvetkovic, Milos A; Sprangers, Remco

    2016-04-07

    The exosome plays an important role in RNA degradation and processing. In archaea, three Rrp41:Rrp42 heterodimers assemble into a barrel like structure that contains a narrow RNA entrance pore and a lumen that contains three active sites. Here, we demonstrate that this quaternary structure of the exosome is important for efficient RNA degradation. We find that the entrance pore of the barrel is required for nM substrate affinity. This strong interaction is crucial for processive substrate degradation and prevents premature release of the RNA from the enzyme. Using methyl TROSY NMR techniques, we establish that the 3' end of the substrate remains highly flexible inside the lumen. As a result, the RNA jumps between the three active sites that all equally participate in substrate degradation. The RNA jumping rate is, however, much faster than the cleavage rate, indicating that not all active site:substrate encounters result in catalysis. Enzymatic turnover therefore benefits from the confinement of the active sites and substrate in the lumen, which ensures that the RNA is at all times bound to one of the active sites. The evolution of the exosome into a hexameric complex and the optimization of its catalytic efficiency were thus likely co-occurring events. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  3. Development of Short Wavelength Infrared Array Detectors for Space Astronomy Application

    NASA Technical Reports Server (NTRS)

    Fazio, Giovanni G.

    1997-01-01

    The Smithsonian Astrophysical Observatory (SAO) and its team - the University of Arizona (UA), the University of Rochester (UR), Santa Barbara Research Center (SBRC), Ames Research Center (ARC), and Goddard Space Flight Center (GSFC) - are carrying out a research program with the goal of developing and optimizing infrared arrays in the 2-27 micron range for space infrared astronomy. This report summarizes research results for the entire grant period 1 January 1992 through 30 June 1996.

  4. Superior long-term stability of a glucose biosensor based on inserted barrel plating gold electrodes.

    PubMed

    Hsu, Cheng-Teng; Hsiao, Hung-Chan; Fang, Mei-Yen; Zen, Jyh-Myng

    2009-10-15

    Disposable one shot usage blood glucose strips are routinely used in the diagnosis and management of diabetes mellitus and their performance can vary greatly. In this paper we critically evaluated the long-term stability of glucose strips made of barrel plating gold electrodes. Compared to other glucose biosensing platforms of vapor deposited palladium and screen printed carbon electrodes, the proposed glucose biosensor was found to show the best stability among the three biosensing platforms in thermal acceleration experiments at 40 degrees C for 6 months with an average bias of 3.4% at glucose concentrations of 5-20 mM. The precision test of this barrel plating gold glucose biosensor also showed the best performance (coefficients of variation in the range of 1.4-2.4%) in thermal acceleration experiments at 40 degrees C, 50 degrees C and 70 degrees C for 27 days. Error grid analysis revealed that all measurements fell in zone A and zone B. Regression analysis showed no significant difference between the proposed biosensor and the reference method at 99% confidence level. The amperometric glucose biosensor fabricated by inserting two barrel plating gold electrodes onto an injection-molding plastic base followed by immobilizing with a bio-reagent layer and membrane was very impressive with a long-term stability up to 2.5 years at 25 degrees C. Overall, these results indicated that the glucose oxidase/barrel plating gold biosensing platform is ideal for long-term accurate glycemic control.

  5. Neural cell adhesion molecule, NCAM, regulates thalamocortical axon pathfinding and the organization of the cortical somatosensory representation in mouse

    PubMed Central

    Enriquez-Barreto, Lilian; Palazzetti, Cecilia; Brennaman, Leann H.; Maness, Patricia F.; Fairén, Alfonso

    2012-01-01

    To study the potential role of neural cell adhesion molecule (NCAM) in the development of thalamocortical (TC) axon topography, wild type, and NCAM null mutant mice were analyzed for NCAM expression, projection, and targeting of TC afferents within the somatosensory area of the neocortex. Here we report that NCAM and its α-2,8-linked polysialic acid (PSA) are expressed in developing TC axons during projection to the neocortex. Pathfinding of TC axons in wild type and null mutant mice was mapped using anterograde DiI labeling. At embryonic day E16.5, null mutant mice displayed misguided TC axons in the dorsal telencephalon, but not in the ventral telencephalon, an intermediate target that initially sorts TC axons toward correct neocortical areas. During the early postnatal period, rostrolateral TC axons within the internal capsule along the ventral telencephalon adopted distorted trajectories in the ventral telencephalon and failed to reach the neocortex in NCAM null mutant animals. NCAM null mutants showed abnormal segregation of layer IV barrels in a restricted portion of the somatosensory cortex. As shown by Nissl and cytochrome oxidase staining, barrels of the anterolateral barrel subfield (ALBSF) and the most distal barrels of the posteromedial barrel subfield (PMBSF) did not segregate properly in null mutant mice. These results indicate a novel role for NCAM in axonal pathfinding and topographic sorting of TC axons, which may be important for the function of specific territories of sensory representation in the somatosensory cortex. PMID:22723769

  6. Functional recovery of neuronal activity in rat whisker-barrel cortex sensory pathway from freezing injury after transplantation of adult bone marrow stromal cells.

    PubMed

    Mori, Kentaro; Iwata, Junko; Miyazaki, Masahiro; Nakao, Yasuaki; Maeda, Minoru

    2005-07-01

    The effect of transplantation of adult bone marrow stromal cells (MSCs) into the freeze-lesioned left barrel field cortex in the rat was investigated by measurement of local cerebral glucose utilization (lCMR(glc)) in the anatomic structures of the whisker-to-barrel cortex sensory pathway. Bone marrow stromal cells or phosphate-buffered saline (PBS) were injected intracerebrally into the boundary zone 1 h after induction of the freezing cortical lesion. Three weeks after surgery, the 2-[(14)C]deoxyglucose method was used to measure lCMR(glc) during right whisker stimulation. The volume of the primary necrotic freezing lesion was significantly reduced (P<0.05), and secondary retrograde degeneration in the left ventral posteromedial (VPM) thalamic nucleus was diminished in the MSC-treated group. Local cerebral glucose utilization measurements showed that the freezing cortical lesion did not alter the metabolic responses to stimulation in the brain stem trigeminal nuclei, but eliminated the responses in the left VPM nucleus and periphery of the barrel cortex in the PBS-treated group. The left/right (stimulated/unstimulated) lCMR(glc) ratios were significantly improved in both the VPM nucleus and periphery of the barrel cortex in the MSC-treated group compared with the PBS-treated group (P<0.05). These results indicate that MSC transplantation in adults may stimulate metabolic and functional recovery in injured neuronal pathways.

  7. Neurons immunoreactive for vasoactive intestinal polypeptide in the rat primary somatosensory cortex: morphology and spatial relationship to barrel-related columns.

    PubMed

    Bayraktar, T; Welker, E; Freund, T F; Zilles, K; Staiger, J F

    2000-05-08

    Vasoactive intestinal polypeptide (VIP) in neocortex affects neuronal excitability as well as cortical blood flow and metabolism. Interneurons immunoreactive for VIP (VIP-IR neurons) are characterized by their predominantly bipolar appearance and the radial orientation of their main dendrites. In order to determine whether the morphology of VIP-IR neurons is related to the functional organization of the cortex into vertical columns, we combined both immunostaining of neurons containing VIP and cytochrome oxidase histochemistry for visualizing barrels, morphological layer IV correlates of functional columns, in the primary somatosensory (barrel) cortex of rats. VIP-IR neurons were localized in supragranular (48%), granular (16%), and infragranular layers (36%) as well as in the white matter. In the granular layer, a clear trend that more neurons were located in interbarrel septa rather than in barrels could be observed, resulting in a neuronal density which was about one-third higher in the septal area. VIP-IR neurons from the different cortical layers were three-dimensionally reconstructed from serial sections by using a computer microscope system. The neurons were mostly bipolar. Striking morphological differences in both axonal and dendritic trees were found between neurons whose cell bodies were located in supragranular, granular, and the upper part of infragranular layers, and those whose cell bodies were located in the area below. The former had dendrites which often reached layer I, where they bifurcated several times, and axonal trees which were particularly oriented vertically, with a tangential extent smaller than the width of barrels. Therefore, these neurons were mostly confined to either a barrel- or septum-related column. By contrast, the dendrites of neurons of the latter group did not reach the granular layer. Furthermore, these neurons had axons with sometimes very long horizontal collaterals, which often spanned two, in one case three, barrel columns. It is proposed that the differential morphology of neurons with different locations as stated above parallels to some extent the divergence of input streaming into the corresponding layer-defined areas. As a possible consequence of this, VIP-IR neurons may be capable of adapting the excitability and metabolism of cortical compartments either in a spatially limited or more extensive way. Copyright 2000 Wiley-Liss, Inc.

  8. Unconventional Liquids, Peak Oil and Climate Change

    NASA Astrophysics Data System (ADS)

    Hughes, J. D.

    2015-12-01

    Oil is the largest source of primary energy in the world, at 32% of 2014 consumption. Forecasts by the International Energy Agency suggest oil will continue to provide the largest share of global energy through 2040, even with new policies to mitigate greenhouse gas emissions. The IPCC's Representative Concentration Pathway (RCP) scenarios indicate that between 1.5 and 3.8 trillion barrels of oil will be burnt between 2015 and 2100. Various sources suggest that the world has 5 to 6 trillion barrels of remaining recoverable oil, more than half of which are in low grade deposits. Although oil sands and extra heavy oil are claimed to hold 1.5 trillion barrels, assessments of major deposits in the Canadian oil sands and the Venezuela Orinoco Belt, which hold the bulk of these resources, total less than 500 billion barrels of recoverable oil. Kerogen oil (oil shale), which has never been produced in anything but miniscule volumes, comprises an additional trillion barrels of these estimates. These unconventional deposits are very different from the conventional oil of the past as: - they are rate constrained, as they require massive upfront capital investments and lengthy construction periods, and therefore cannot be scaled up quickly in response to declines in conventional production. - they are expensive, both in terms of cost per barrel and the large energy inputs required for production. The best in situ oil sands deposits may yield an energy return of 3:1 and kerogen oil even less if it ever becomes commercially viable. This compares to 10:1 or more for conventional oil. Shale oil (light tight oil), may yield another 300 billion barrels worldwide, but suffers from high decline rates, expensive wells and limited availability of high quality deposits. The most productive and economically viable portions of these unconventional deposits tend to be exploited first, leaving the less productive, higher cost oil for later. As a result, increasing global oil consumption will prove extremely difficult beyond the next few years, even with much higher prices. Long term oil consumption assumptions in RCP4.5, RCP6 and RCP8.5 are therefore too high, given the geological and economic characteristics of remaining recoverable resources. Consumption of other fuels would need to be increased to retain the radiative forcing in these RCP scenarios.

  9. Terrestrial Gamma Flashes at Ground Level - TETRA-II Instrumentation

    NASA Astrophysics Data System (ADS)

    Pleshinger, D. J.; Adams, C.; Al-Nussirat, S.; Bai, S.; Banadaki, Y.; Bitzer, P. M.; Cherry, M. L.; Hoffmann, J.; Khosravi, E.; Legault, M.; Orang, M.; Rodriguez, R.; Smith, D.; Trepanier, J. C.; Sunda-Meya, A.; Zimmer, N.

    2017-12-01

    The TGF and Energetic Thunderstorm Rooftop Array (TETRA-II) consists of an array of BGO scintillators to detect bursts of gamma rays from thunderstorms. TETRA-II will have approximately an order of magnitude greater sensitivity for individual flashes than TETRA-I, an original array of NaI scintillators at Louisiana State University that detected 37 millisecond-scale bursts of gamma rays from 2010-2015. The BGO scintillators increase the energy range of particles detected to 10 MeV and are placed in 20 detectors boxes, each with 1180 cm3 of BGO, at 4 separate locations: the campus of Louisiana State University in Baton Rouge, Louisiana; the campus of the University of Puerto Rico at Utuado, Puerto Rico; the Centro Nacional de Metrologia de Panama (CENAMEP) in Panama City, Panama; and the Severe Weather Institute and Radar & Lightning Laboratories in Huntsville, Alabama. The data are read out with 12 microsecond resolution by National Instruments PCIe 6351 high speed data acquisition cards, with timestamps determined from a 20 MHz clock and a GPS board recording a pulse per second. Details of the array and its instrumentation, along with an overview of initial results, will be presented.

  10. University-School-Community Partnerships for Youth Development and Democratic Renewal

    ERIC Educational Resources Information Center

    Harkavy, Ira; Hartley, Matthew

    2009-01-01

    Democratic partnerships of universities, schools, and an array of neighborhood and community organizations are the most promising means of improving the lives of our nation's young people. Over the past two decades, many colleges and universities have been experiencing a renaissance in engagement activities. Universities, once ivory towers, have…

  11. Assessment of undiscovered conventional and continuous oil and gas resources of the Baltic Depression Province, 2014

    USGS Publications Warehouse

    Brownfield, Michael E.; Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Pitman, Janet K.; Tennyson, Marilyn E.; Gaswirth, Stephanie B.; Mercier, Tracey J.; Le, Phuong A.; Leathers, Heidi M.

    2015-01-01

    The U.S. Geological Survey estimated mean volumes of undiscovered, technically recoverable resources of 282 million barrels of conventional oil, 576 billion cubic feet of conventional gas, 1.3 billion barrels of continuous oil, and 4.6 trillion cubic feet of shale gas in the Baltic Depression Province.

  12. High speed machining of space shuttle external tank liquid hydrogen barrel panel

    NASA Technical Reports Server (NTRS)

    Hankins, J. D.

    1983-01-01

    Actual and projected optimum High Speed Machining data for producing shuttle external tank liquid hydrogen barrel panels of aluminum alloy 2219-T87 are reported. The data included various machining parameters; e.g., spindle speeds, cutting speed, table feed, chip load, metal removal rate, horsepower, cutting efficiency, cutter wear (lack of) and chip removal methods.

  13. 1. INTERIOR VIEW WITH NAVE, BARREL VAULTED SOLEA, ICONOSTAS WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. INTERIOR VIEW WITH NAVE, BARREL VAULTED SOLEA, ICONOSTAS WITH ICON AND SANCTUARY. IN ARCH ABOVE THE SANCTUARY IS THE TABLE OF ABRAHAM. THE ICONOSTAS INCLUDES ICONS OF THE ARCHANGEL MICHAEL, THE HOLY TRINITY, MOTHER OF GOD HOLDING THE CHRIST CHILD, JESUS. - Holy Trinity-Holy Cross Greek Orthodox Church, 200 Nineteenth Street South, Birmingham, Jefferson County, AL

  14. High speed machining of space shuttle external tank liquid hydrogen barrel panel

    NASA Astrophysics Data System (ADS)

    Hankins, J. D.

    1983-11-01

    Actual and projected optimum High Speed Machining data for producing shuttle external tank liquid hydrogen barrel panels of aluminum alloy 2219-T87 are reported. The data included various machining parameters; e.g., spindle speeds, cutting speed, table feed, chip load, metal removal rate, horsepower, cutting efficiency, cutter wear (lack of) and chip removal methods.

  15. Sealing Apparatus For Exclusion of Water From Underwater Gun Barrels.

    DTIC Science & Technology

    1996-03-03

    4,821,441. For example, U.S. Patent No. 44,631 discloses a 11 submarine shot conductor having an India- rubber valve mounted on 12 the open end of the...11 ... barrel of the device is closed by a closure device made by a 12 material which may be perforated by the projectile disposed 13 inside the

  16. 40 CFR 74.20 - Data for baseline and alternative baseline.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... consumed, expressed in thousands of tons for coal, thousands of barrels for oil, and million standard cubic... measure. (ii) Monthly or annual heat content of fuel consumed for each type of fuel consumed, expressed in British thermal units (Btu) per pound for coal, Btu per barrel for oil, and Btu per standard cubic foot...

  17. Construction of Ag/AgCl Reference Electrode from Used Felt-Tipped Pen Barrel for Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Inamdar, Shaukatali N.; Bhat, Mohsin A.; Haram, Santosh K.

    2009-01-01

    A reference electrode is one of the prerequisites of electrochemical investigations. Many electrodes are commercially available but are expensive and prone to accidental breakage by students. Here we report a simple, easy-to-fabricate, inexpensive, reliable, unbreakable, and reproducible Ag/AgCl reference electrode. The empty barrel of a…

  18. 77 FR 37321 - Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... 1625-AA00 Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN AGENCY: Coast Guard, DHS. ACTION... suspected to contain munitions waste materials which were dumped in the 1960's in a portion of Lake Superior... offshore in a portion of Lake Superior approximately 50 years ago. C. Discussion of the Final Rule The...

  19. Assessment of undiscovered continuous oil and gas resources in the Monterey Formation, Los Angeles Basin Province, California, 2015

    USGS Publications Warehouse

    Tennyson, Marilyn E.; Charpentier, Ronald R.; Klett, Timothy R.; Brownfield, Michael E.; Pitman, Janet K.; Gaswirth, Stephanie B.; Hawkins, Sarah J.; Le, Phuong A.; Lillis, Paul G.; Marra, Kristen R.; Mercier, Tracey J.; Leathers-Miller, Heidi M.; Schenk, Christopher J.

    2016-07-08

    Using a geology-based assessment methodology, the U.S. Geological Survey assessed technically recoverable mean resources of 13 million barrels of oil, 22 billion cubic feet of gas, and 1 million barrels of natural gas liquids in the Monterey Formation of the Los Angeles Basin Province, California.

  20. Molecular Correlates of Cortical Network Modulation by Long-Term Sensory Experience in the Adult Rat Barrel Cortex

    ERIC Educational Resources Information Center

    Vallès, Astrid; Granic, Ivica; De Weerd, Peter; Martens, Gerard J. M.

    2014-01-01

    Modulation of cortical network connectivity is crucial for an adaptive response to experience. In the rat barrel cortex, long-term sensory stimulation induces cortical network modifications and neuronal response changes of which the molecular basis is unknown. Here, we show that long-term somatosensory stimulation by enriched environment…

  1. 26 CFR 1.613A-7 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... from such wells), refers to wells located in the United States or in a possession of the United States...) for natural gas has been made. See § 1.613A-5. (j) Barrel. The term barrel means 42 United States... oil or natural gas, which are made outside the United States shall be disregarded if no domestic...

  2. Correlation of the Characteristics of Single-Cylinder and Flight Engines in Tests of High-Performance Fuels in an Air-Cooled Engine I : Cooling Characteristics

    NASA Technical Reports Server (NTRS)

    Wilson, Robert W.; Richard, Paul H.; Brown, Kenneth D.

    1945-01-01

    Variable charge-air flow, cooling-air pressure drop, and fuel-air ration investigations were conducted to determine the cooling characteristics of a full-scale air-cooled single cylinder on a CUE setup. The data are compared with similar data that were available for the same model multicylinder engine tested in flight in a four-engine airplane. The cylinder-head cooling correlations were the same for both the single-cylinder and the flight engine. The cooling correlations for the barrels differed slightly in that the barrel of the single-cylinder engine runs cooler than the barrel of te flight engine for the same head temperatures and engine conditions.

  3. Firearm suppressor having enhanced thermal management for rapid heat dissipation

    DOEpatents

    Moss, William C.; Anderson, Andrew T.

    2014-08-19

    A suppressor is disclosed for use with a weapon having a barrel through which a bullet is fired. The suppressor has an inner portion having a bore extending coaxially therethrough. The inner portion is adapted to be secured to a distal end of the barrel. A plurality of axial flow segments project radially from the inner portion and form axial flow paths through which expanding propellant gasses discharged from the barrel flow through. The axial flow segments have radially extending wall portions that define sections which may be filled with thermally conductive material, which in one example is a thermally conductive foam. The conductive foam helps to dissipate heat deposited within the suppressor during firing of the weapon.

  4. Isolation and proteomic analysis of Chlamydomonas centrioles.

    PubMed

    Keller, Lani C; Marshall, Wallace F

    2008-01-01

    Centrioles are barrel-shaped cytoskeletal organelles composed of nine triplet microtubules blades arranged in a pinwheel-shaped array. Centrioles are required for recruitment of pericentriolar material (PCM) during centrosome formation, and they act as basal bodies, which are necessary for the outgrowth of cilia and flagella. Despite being described over a hundred years ago, centrioles are still among the most enigmatic organelles in all of cell biology. To gain molecular insights into the function and assembly of centrioles, we sought to determine the composition of the centriole proteome. Here, we describe a method that allows for the isolation of virtually "naked" centrioles, with little to no obscuring PCM, from the green alga, Chlamydomonas. Proteomic analysis of this material provided evidence that multiple human disease gene products encode protein components of the centriole, including genes involved in Meckel syndrome and Oral-Facial-Digital syndrome. Isolated centrioles can be used in combination with a wide variety of biochemical assays in addition to being utilized as a source for proteomic analysis.

  5. Large Area Nondestructive Evaluation of a Fatigue Loaded Composite Structure

    NASA Technical Reports Server (NTRS)

    Zalameda, Joseph N.; Burke, Eric R.; Horne, Michael R.; Madaras, Eric I.

    2016-01-01

    Large area nondestructive evaluation (NDE) inspections are required for fatigue testing of composite structures to track damage initiation and growth. Of particular interest is the progression of damage leading to ultimate failure to validate damage progression models. In this work, passive thermography and acoustic emission NDE were used to track damage growth up to failure of a composite three-stringer panel. Fourteen acoustic emission sensors were placed on the composite panel. The signals from the array were acquired simultaneously and allowed for acoustic emission location. In addition, real time thermal data of the composite structure were acquired during loading. Details are presented on the mapping of the acoustic emission locations directly onto the thermal imagery to confirm areas of damage growth leading to ultimate failure. This required synchronizing the acoustic emission and thermal data with the applied loading. In addition, processing of the thermal imagery which included contrast enhancement, removal of optical barrel distortion and correction of angular rotation before mapping the acoustic event locations are discussed.

  6. Comparison of two suspension arrays for simultaneous detection of five biothreat bacterial in powder samples.

    PubMed

    Yang, Yu; Wang, Jing; Wen, Haiyan; Liu, Hengchuan

    2012-01-01

    We have developed novel Bio-Plex assays for simultaneous detection of Bacillus anthracis, Yersinia pestis, Brucella spp., Francisella tularensis, and Burkholderia pseudomallei. Universal primers were used to amplify highly conserved region located within the 16S rRNA amplicon, followed by hybridized to pathogen-specific probes for identification of these five organisms. The other assay is based on multiplex PCR to simultaneously amplify five species-specific pathogen identification-targeted regions unique to individual pathogen. Both of the two arrays are validated to be flexible and sensitive for simultaneous detection of bioterrorism bacteria. However, universal primer PCR-based array could not identify Bacillus anthracis, Yersinia pestis, and Brucella spp. at the species level because of the high conservation of 16S rDNA of the same genus. The two suspension arrays can be utilized to detect Bacillus anthracis sterne spore and Yersinia pestis EV76 from mimic "write powder" samples, they also proved that the suspension array system will be valuable tools for diagnosis of bacterial biothreat agents in environmental samples.

  7. Integrated residential photovoltaic array development

    NASA Astrophysics Data System (ADS)

    Shepard, N. F., Jr.

    1981-12-01

    An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

  8. Integrated residential photovoltaic array development

    NASA Technical Reports Server (NTRS)

    Shepard, N. F., Jr.

    1981-01-01

    An advanced, universally-mountable, integrated residential photovoltaic array concept was defined based upon an in-depth formulation and evaluation of three candidate approaches which were synthesized from existing or proposed residential array concepts. The impact of module circuitry and process sequence is considered and technology gaps and performance drivers associated with residential photovoltaic array concepts are identified. The actual learning experience gained from the comparison of the problem areas of the hexagonal shingle design with the rectangular module design led to what is considered an advanced array concept. Building the laboratory mockup provided actual experience and the opportunity to uncover additional technology gaps.

  9. The history of early low frequency radio astronomy in Australia. 9: the University of Tasmania's Llanherne (Hobart Airport) Field Station during the 1960s-1980s

    NASA Astrophysics Data System (ADS)

    George, Martin; Orchiston, Wayne; Wielebinski, Richard

    2018-04-01

    Beginning in the early 1960s, the University of Tasmania became very involved in low frequency radio astronomical studies, which was to continue into the 1980s. Although important low frequency arrays were set up at Penna and Richmond, the main location for this activity by the University was in the vicinity of Hobart Airport, known as Llanherne. This paper describes the work performed there at frequencies of 30 MHz and below, mainly for studying radio emission from Jupiter and the Galaxy. The largest of the installations was the Llanherne Low Frequency Array, a 640 × 640 m antenna array adjacent to Holyman Avenue; it was well known to the public because of its high visibility to airport patrons. Other installations were set up closer to the airport runway. Various researchers, including Graeme Ellis, Hilary Cane and others, made observations at Llanherne.

  10. Electrostatic networks control plug stabilization in the PapC usher.

    PubMed

    Pham, Thieng; Henderson, Nadine S; Werneburg, Glenn T; Thanassi, David G; Delcour, Anne H

    2015-01-01

    The PapC usher, a β-barrel pore in the outer membrane of uropathogenic Escherichia coli, is used for assembly of the P pilus, a key virulence factor in bacterial colonization of human kidney cells. Each PapC protein is composed of a 24-stranded β-barrel channel, flanked by N- and C-terminal globular domains protruding into the periplasm, and occluded by a plug domain (PD). The PD is displaced from the channel towards the periplasm during pilus biogenesis, but the molecular mechanism for PD displacement remains unclear. Two structural features within the β-barrel, an α-helix and β5-6 hairpin loop, may play roles in controlling plug stabilization. Here we have tested clusters of residues at the interface of the plug, barrel, α-helix and hairpin, which participate in electrostatic networks. To assess the roles of these residues in plug stabilization, we used patch-clamp electrophysiology to compare the activity of wild-type and mutant PapC channels containing alanine substitutions at these sites. Mutations interrupting each of two salt bridge networks were relatively ineffective in disrupting plug stabilization. However, mutation of two pairs of arginines located at the inner and the outer surfaces of the PD resulted in an enhanced propensity for plug displacement. One arginine pair involved in a repulsive interaction between the linkers that tether the plug to the β-barrel was particularly sensitive to mutation. These results suggest that plug displacement, which is necessary for pilus assembly and translocation, may require a weakening of key electrostatic interactions between the plug linkers, and the plug and the α-helix.

  11. BamA β16C strand and periplasmic turns are critical for outer membrane protein insertion and assembly.

    PubMed

    Gu, Yinghong; Zeng, Yi; Wang, Zhongshan; Dong, Changjiang

    2017-11-21

    Outer membrane (OM) β-barrel proteins play important roles in importing nutrients, exporting wastes and conducting signals in Gram-negative bacteria, mitochondria and chloroplasts. The outer membrane proteins (OMPs) are inserted and assembled into the OM by OMP85 family proteins. In Escherichia coli , the β-barrel assembly machinery (BAM) contains four lipoproteins such as BamB, BamC, BamD and BamE, and one OMP BamA, forming a 'top hat'-like structure. Structural and functional studies of the E. coli BAM machinery have revealed that the rotation of periplasmic ring may trigger the barrel β1C-β6C scissor-like movement that promote the unfolded OMP insertion without using ATP. Here, we report the BamA C-terminal barrel structure of Salmonella enterica Typhimurium str. LT2 and functional assays, which reveal that the BamA's C-terminal residue Trp, the β16C strand of the barrel and the periplasmic turns are critical for the functionality of BamA. These findings indicate that the unique β16C strand and the periplasmic turns of BamA are important for the outer membrane insertion and assembly. The periplasmic turns might mediate the rotation of the periplasmic ring to the scissor-like movement of BamA β1C-β6C, triggering the OMP insertion. These results are important for understanding the OMP insertion in Gram-negative bacteria, as well as in mitochondria and chloroplasts. © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  12. Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue

    PubMed Central

    Haack, Nicole; Durry, Simone; Kafitz, Karl W.; Chesler, Mitchell; Rose, Christine R.

    2015-01-01

    Electrical activity in the brain is accompanied by significant ion fluxes across membranes, resulting in complex changes in the extracellular concentration of all major ions. As these ion shifts bear significant functional consequences, their quantitative determination is often required to understand the function and dysfunction of neural networks under physiological and pathophysiological conditions. In the present study, we demonstrate the fabrication and calibration of double-barreled ion-selective microelectrodes, which have proven to be excellent tools for such measurements in brain tissue. Moreover, so-called “concentric” ion-selective microelectrodes are also described, which, based on their different design, offer a far better temporal resolution of fast ion changes. We then show how these electrodes can be employed in acute brain slice preparations of the mouse hippocampus. Using double-barreled, potassium-selective microelectrodes, changes in the extracellular potassium concentration ([K+]o) in response to exogenous application of glutamate receptor agonists or during epileptiform activity are demonstrated. Furthermore, we illustrate the response characteristics of sodium-sensitive, double-barreled and concentric electrodes and compare their detection of changes in the extracellular sodium concentration ([Na+]o) evoked by bath or pressure application of drugs. These measurements show that while response amplitudes are similar, the concentric sodium microelectrodes display a superior signal-to-noise ratio and response time as compared to the double-barreled design. Generally, the demonstrated procedures will be easily transferable to measurement of other ions species, including pH or calcium, and will also be applicable to other preparations. PMID:26381747

  13. 78 FR 15364 - Gulf Crossing Pipeline Company LLC; Notice of Intent To Prepare an Environmental Assessment for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ... Sherman Compressor Station located 10 miles northeast of Sherman, Texas, to Panda Sherman Power, LLC's... barrel and meter station consisting of a 16-inch receiver barrel and associated piping and valves at MP... control station to be built, owned, and operated by ETP. The general location of the project facilities is...

  14. LINC Modeling of August 19, 2004 Queen City Barrel Company Fire In Cincinnati, OH

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dillon, M B; Nasstrom, J S; Baskett, R L

    This report details the information received, assumptions made, actions taken, and products delivered by the Lawrence Livermore National Laboratory (LLNL) during the August 19, 2004 fire at the Queen City Barrel Company (QCB) in Cincinnati, OH. During the course of the event, LLNL provided four sets of plume model products to various Cincinnati emergency response organizations.

  15. Assessment of undiscovered oil and gas resources of the Volga-Ural Region Province, Russia and Kazakhstan, 2010

    USGS Publications Warehouse

    Klett, T.R.; Schenk, Christopher J.; Charpentier, Ronald R.; Brownfield, Michael E.; Pitman, Janet K.; Cook, Troy A.; Tennyson, Marilyn E.

    2010-01-01

    The U.S. Geological Survey estimated mean volumes of technically recoverable, conventional, undiscovered petroleum resources at 1.4 billion barrels of crude oil, 2.4 trillion cubic feet of natural gas, and 85 million barrels of natural gas liquids for the Volga-Ural Region Province, using a geology-based assessment methodology.

  16. 19 CFR 10.5 - Shooks and staves; cloth boards; port director's account.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Shooks and staves produced in the United States and returned in the form of complete boxes or barrels in... country are ready to be assembled into boxes or barrels without further cutting to size; except that box shooks may be exported in double lengths and cut abroad. The number of boxes made from such shooks which...

  17. 19 CFR 10.5 - Shooks and staves; cloth boards; port director's account.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Shooks and staves produced in the United States and returned in the form of complete boxes or barrels in... country are ready to be assembled into boxes or barrels without further cutting to size; except that box shooks may be exported in double lengths and cut abroad. The number of boxes made from such shooks which...

  18. 19 CFR 10.5 - Shooks and staves; cloth boards; port director's account.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Shooks and staves produced in the United States and returned in the form of complete boxes or barrels in... country are ready to be assembled into boxes or barrels without further cutting to size; except that box shooks may be exported in double lengths and cut abroad. The number of boxes made from such shooks which...

  19. 19 CFR 10.5 - Shooks and staves; cloth boards; port director's account.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Shooks and staves produced in the United States and returned in the form of complete boxes or barrels in... country are ready to be assembled into boxes or barrels without further cutting to size; except that box shooks may be exported in double lengths and cut abroad. The number of boxes made from such shooks which...

  20. 19 CFR 10.5 - Shooks and staves; cloth boards; port director's account.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Shooks and staves produced in the United States and returned in the form of complete boxes or barrels in... country are ready to be assembled into boxes or barrels without further cutting to size; except that box shooks may be exported in double lengths and cut abroad. The number of boxes made from such shooks which...

  1. 27 CFR 25.152 - Reduced rate of tax for certain brewers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Liability for Tax § 25.152 Reduced... reduced rate of tax on the first 60,000 barrels of beer removed for consumption or sale by a brewer during... the beer at a qualified brewery in the United States; (2) May not produce more than 2,000,000 barrels...

  2. 27 CFR 25.152 - Reduced rate of tax for certain brewers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Liability for Tax § 25.152 Reduced... reduced rate of tax on the first 60,000 barrels of beer removed for consumption or sale by a brewer during... the beer at a qualified brewery in the United States; (2) May not produce more than 2,000,000 barrels...

  3. 27 CFR 25.152 - Reduced rate of tax for certain brewers.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Liability for Tax § 25.152 Reduced... reduced rate of tax on the first 60,000 barrels of beer removed for consumption or sale by a brewer during... the beer at a qualified brewery in the United States; (2) May not produce more than 2,000,000 barrels...

  4. 27 CFR 25.152 - Reduced rate of tax for certain brewers.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Liability for Tax § 25.152 Reduced... reduced rate of tax on the first 60,000 barrels of beer removed for consumption or sale by a brewer during... the beer at a qualified brewery in the United States; (2) May not produce more than 2,000,000 barrels...

  5. Report to the Congress on alternative methods for the Strategic Petroleum Reserve

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1990-02-01

    The purpose of this study is to fulfill the requirements of Public Law No. 101-46, approved June 30, 1989. The study describes and evaluates alternative methods for financing the future expansion of the Strategic petroleum Reserve (SPR), both to the current target level of 750 million barrels and to potential future levels of up to one billion barrels.

  6. 27 CFR 25.152 - Reduced rate of tax for certain brewers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Liability for Tax § 25.152 Reduced... reduced rate of tax on the first 60,000 barrels of beer removed for consumption or sale by a brewer during... the beer at a qualified brewery in the United States; (2) May not produce more than 2,000,000 barrels...

  7. Assessment of undiscovered oil and gas resources in the Paradox Basin Province, Utah, Colorado, New Mexico, and Arizona, 2011

    USGS Publications Warehouse

    Whidden, Katherine J.

    2012-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 560 million barrels of undiscovered oil, 12,701 billion cubic feet of undiscovered natural gas, and 490 million barrels of undiscovered natural gas liquids in the Paradox Basin of Utah, Colorado, New Mexico, and Arizona.

  8. Assessment of undiscovered oil and gas resources in the Cherokee Platform Province area of Kansas, Oklahoma, and Missouri, 2015

    USGS Publications Warehouse

    Drake II, Ronald M.; Hatch, Joseph R.; Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Le, Phuong A.; Leathers, Heidi M.; Brownfield, Michael E.; Gaswirth, Stephanie B.; Marra, Kristen R.; Pitman, Janet K.; Potter, Christopher J.; Tennyson, Marilyn E.

    2015-09-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated mean volumes of undiscovered, technically recoverable resources of 463 million barrels of oil, 11.2 trillion cubic feet of gas, and 35 million barrels of natural gas liquids in the Cherokee Platform Province area of Kansas, Oklahoma, and Missouri.

  9. Sorbent materials for rapid remediation of wash water during radiological event relief

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jolin, William C.; Kaminski, Michael

    2016-11-01

    Procedures for removing harmful radiation from interior and exterior surfaces of homes and businesses after a nuclear or radiological disaster may generate large volumes of radiologically contaminated waste water. Rather than releasing this waste water to potentially contaminate surrounding areas, it is preferable to treat it onsite. Retention barrels are a viable option because of their simplicity in preparation and availability of possible sorbent materials. This study investigated the use of aluminosilicate clay minerals as sorbent materials to retain 137Cs, 85Sr, and 152Eu. Vermiculite strongly retained 137Cs, though other radionuclides displayed diminished affinity for the surface. Montmorillonite exhibited increased affinitymore » to sorb 85Sr and 152Eu in the presence of higher concentrations of 137Cs. To simulate flow within retention barrels, vermiculite was mixed with sand and used in small-scale column experiments. The GoldSim contaminate fate module was used to model breakthrough and assess the feasibility of using clay minerals as sorbent materials in retention barrels. The modeled radionuclide breakthrough profiles suggest that vermiculite-sand and montmorillonite-sand filled barrels could be used for treatment of contaminated water generated from field operations.« less

  10. Dead zone analysis of ECAL barrel modules under static and dynamic load

    NASA Astrophysics Data System (ADS)

    Pierre-Emile, T.; Anduze, M.

    2018-03-01

    In the context of ILD project, impact studies of environmental loads on the Electromagnetic CALorimeter (ECAL) have been initiated. The ECAL part considered is the barrel and it consists of several independent modules which are mounted on the Hadronic CALorimeter barrel (HCAL) itself mounted on the cryostat coil and the yoke. The estimate of the gap required between each ECAL modules is fundamental to define the assembly step and avoid mechanical contacts over the barrel lifetime. In the meantime, it has to be done in consideration to the dead spaces reduction and detector hermiticity optimization. Several Finite Element Analysis (FEA) with static and dynamic loads have been performed in order to define correctly the minimum values for those gaps. Due to the implantation site of the whole project in Japan, seismic analysis were carried out in addition to the static ones. This article shows results of these analysis done with the Finite Element Method (FEM) in ANSYS. First results show the impact of HCAL design on the ECAL modules motion in static load. The second study dedicated to seismic approach on a larger model (including yoke and cryostat) gives additional results on earthquake consequences.

  11. Improved Kolsky tension bar for high-rate tensile characterization of materials

    NASA Astrophysics Data System (ADS)

    Song, Bo; Antoun, Bonnie R.; Connelly, Kevin; Korellis, John; Lu, Wei-Yang

    2011-04-01

    A new Kolsky tension bar has been re-designed and developed at Sandia National Laboratories, CA. The new design uses the concept that a solid striker is fired to impact an end cap attached to the open end of the gun barrel to generate dynamic tensile loading. The gun barrel here serves as part of the loading device. The incident bar that is connected to the gun barrel and the transmission bar follow the design similar to the Kolsky compression bar. The bar supporting and aligning systems are the same as those in the Kolsky compression bar design described by Song et al (2009 Meas. Sci. Technol. 20 115701). Due to the connection complication among the gun barrel, bars and specimen, stress-wave propagation in the new Kolsky tension bar system is comprehensively analyzed. Based on the stress-wave analysis, the strain gage location on the incident bar needs to be carefully determined. A highly precise laser-beam measurement system is recommended to directly measure the displacement of the incident bar end. Dynamic tensile characterization of a 4330-V steel using this new Kolsky tension bar is presented as an example.

  12. The PANDA Barrel DIRC

    NASA Astrophysics Data System (ADS)

    Schwiening, J.; Ali, A.; Belias, A.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Kalicy, G.; Krebs, M.; Lehmann, D.; Nerling, F.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Traxler, M.; Böhm, M.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Düren, M.; Etzelmüller, E.; Föhl, K.; Hayrapetyan, A.; Kreutzfeld, K.; Merle, O.; Rieke, J.; Schmidt, M.; Wasem, T.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Schlimme, S.; Sfienti, C.; Thiel, M.

    2018-03-01

    The PANDA experiment at the international accelerator Facility for Antiproton and Ion Research in Europe (FAIR) near GSI, Darmstadt, Germany will address fundamental questions of hadron physics. Excellent Particle Identification (PID) over a large range of solid angles and particle momenta will be essential to meet the objectives of the rich physics program. Charged PID for the barrel region of the PANDA target spectrometer will be provided by a DIRC (Detection of Internally Reflected Cherenkov light) detector. The Barrel DIRC will cover the polar angle range of 22o-140o and cleanly separate charged pions from kaons for momenta between 0.5 GeV/c and 3.5 GeV/c with a separation power of at least 3 standard deviations. The design is based on the successful BABAR DIRC and the SuperB FDIRC R&D with several important improvements to optimize the performance for PANDA, such as a focusing lens system, fast timing, a compact fused silica prism as expansion region, and lifetime-enhanced Microchannel-Plate PMTs for photon detection. This article describes the technical design of the PANDA Barrel DIRC and the result of the design validation using a "vertical slice" prototype in hadronic particle beams at the CERN PS.

  13. SiPM photosensors and fast timing readout for the Barrel Time-of-Flight detector in bar PANDA

    NASA Astrophysics Data System (ADS)

    Suzuki, K.

    2018-03-01

    The Barrel Time-of-Flight detector system will be installed in the upcoming bar PANDA experiment at FAIR in Germany. The detector has a barrel shape of phi=0.5 m and 1.8 m long, covering about 5 m2, which corresponds to the laboratory polar angle coverage of 22o<θ<140o. The detector is a scintillation tile hodoscope. A single scintillation tile segment has a dimension of 90× 30 mm2 and 5 mm thickness, and photons are detected by Silicon Photomultipliers at both ends. 4 Silicon Photomultipliers are combined to work as a single sensor in order to increase the sensitive area and to improve the timing performance. In total, the system consists of 1920 scintillator tiles, 3840 readout channels, and makes use of 15360 Silicon Photomultiplier sensors. In this paper, the requirement, design and the result of an actual performance test of the bar PANDA Barrel Time-of-Flight detector are presented. The test shows that the current design fulfils satisfactorily the required timing performance (σt~ 56 ps) and the timing performance depends little on the hit position on the surface.

  14. Dynamics of conical wire array Z-pinch implosions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ampleford, D. J.; Lebedev, S. V.; Bland, S. N.

    2007-10-15

    A modification of the wire array Z pinch, the conical wire array, has applications to the understanding of wire array implosions and potentially to pulse shaping relevant to inertial confinement fusion. Results are presented from imploding conical wire array experiments performed on university scale 1 MA generators--the MAGPIE generator (1 MA, 240 ns) at Imperial College London [I. H. Mitchell et al., Rev. Sci Instrum. 67, 1533 (1996)] and the Nevada Terawatt Facility's Zebra generator (1 MA, 100 ns) at the University of Nevada, Reno [B. Bauer et al., in Dense Z-Pinches, edited by N. Pereira, J. Davis, and P.more » Pulsifer (AIP, New York, 1997), Vol. 409, p. 153]. This paper will discuss the implosion dynamics of conical wire arrays. Data indicate that mass ablation from the wires in this complex system can be reproduced with a rocket model with fixed ablation velocity. Modulations in the ablated plasma are present, the wavelength of which is invariant to a threefold variation in magnetic field strength. The axial variation in the array leads to a zippered precursor column formation. An initial implosion of a magnetic bubble near the cathode is followed by the implosion zippering upwards. Spectroscopic data demonstrating a variation of plasma parameters (e.g., electron temperature) along the Z-pinch axis is discussed, and experimental data are compared to magnetohydrodynamic simulations.« less

  15. Timing and tracking for the Crystal Barrel detector

    NASA Astrophysics Data System (ADS)

    Beck, Reinhard; Brinkmann, Kai; Novotny, Rainer

    2017-01-01

    The aim of the project D.3 is the upgrade of several detector components used in the CBELSA/TAPS experiment at ELSA. The readout of the Crystal Barrel Calorimeter will be extended by a timing branch in order to gain trigger capability for the detector, which will allow to measure completely neutral final states in photoproduction reactions (see projects A.1 and C.5). Additionally, the readout of the inner crystals of the TAPS detector, which covers the forward opening of the Crystal Barrel Calorimeter, will be modified to be capable of high event rates due to the intensity upgrade of ELSA. Furthermore, a full-scale prototype Time Projection Chamber (TPC) has been built to be used as a new central tracker for the CBELSA/TAPS experiment at ELSA and the FOPI experiment at GSI.

  16. Calibration of CMS Electromagnetic Calorimeter at LHC startup

    NASA Astrophysics Data System (ADS)

    Paramatti, Riccardo

    2011-04-01

    The first 7 TeV LHC collisions recorded with the CMS detector have been used to perform a channel-by-channel calibration of the electromagnetic calorimeter (ECAL). Decays of π° and η into two photons as well as the azimuthal symmetry of the average energy deposition at a given pseudorapidity are utilized to equalize the response of the individual channels. The ECAL comprises a central barrel section and two endcaps. Based on an integrated luminosity of ~ 100 nb-1 a channel-by-channel in-situ calibration precision of 1.15% has been achieved in the barrel ECAL in the pseudorapidity region |η| < 0.8. The energy scale of the ECAL has been investigated and found to agree with the simulation to within 1% in the barrel and 3% in the endcaps.

  17. High density protein crystal growth

    NASA Technical Reports Server (NTRS)

    Rouleau, Robyn (Inventor); Hedden, Douglas Keith (Inventor); Delucas, Lawrence (Inventor)

    2004-01-01

    A protein crystal growth assembly including a crystal growth cell and further including a cell body having a top side and a bottom side and a first aperture defined therethrough, the cell body having opposing first and second sides and a second aperture defined therethrough. A cell barrel is disposed within the cell body, the cell barrel defining a cavity alignable with the first aperture of the cell body, the cell barrel being rotatable within the second aperture. A reservoir is coupled to the bottom side of the cell body and a cap having a top side is disposed on the top side of the cell body. The protein crystal growth assembly may be employed in methods including vapor diffusion crystallization, liquid to liquid crystallization, batch crystallization, and temperature induction batch mode crystallization.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Crawford, E.

    Higher wellhead prices are not expected to bring on a significant increase in supplies of oil and natural gas from new outer continental shelf (OCS) reservoirs between now and 1982. Between 1982 and 1987, however, the situation should change: if 1987 prices range from $7.50 to $25 per barrel, supplies are expected to increase from two to 3.5 million barrels per day, respectively. These results from an Arthur D. Little Co. study are based on the assumption of continued OCS leasing and development, although uncertainties remain about the extent of recoverable reserves. For example, no indications of commercial hydrocarbons havemore » been found in the Gulf of Alaska for the three wells dug so far. In general a price of $20 per barrel is needed to make the risky exploration worthwhile for oil companies. (DCK)« less

  19. Photovoltaic array: Power conditioner interface characteristics

    NASA Technical Reports Server (NTRS)

    Gonzalez, C. C.; Hill, G. M.; Ross, R. G., Jr.

    1982-01-01

    The electrical output (power, current, and voltage) of flat plate solar arrays changes constantly, due primarily to changes in cell temperature and irradiance level. As a result, array loads such as dc-to-ac power conditioners must be capable of accommodating widely varying input levels while maintaining operation at or near the maximum power point of the array. The array operating characteristics and extreme output limits necessary for the systematic design of array load interfaces under a wide variety of climatic conditions are studied. A number of interface parameters are examined, including optimum operating voltage, voltage energy, maximum power and current limits, and maximum open circuit voltage. The effect of array degradation and I-V curve fill factor or the array power conditioner interface is also discussed. Results are presented as normalized ratios of power conditioner parameters to array parameters, making the results universally applicable to a wide variety of system sizes, sites, and operating modes.

  20. Comparative Noise Performance of Portable Broadband Sensor Emplacements

    NASA Astrophysics Data System (ADS)

    Sweet, Justin; Arias-Dotson, Eliana; Beaudoin, Bruce; Anderson, Kent

    2015-04-01

    IRIS PASSCAL has supported portable broadband seismic experiments for close to 30 years. During that time we have seen a variety of sensor vaults deployed. The vaults deployed fall into two broad categories, a PASSCAL style vault and a Flexible Array style vault. The PASSCAL vault is constructed of materials available in-county and it is the Principle Investigator (PI) who establishes the actual field deployed design. These vaults generally are a large barrel placed in a ~1 m deep hole. A small pier, decoupled from the barrel, is fashioned in the bottom of the vault (either cement, paving stone or tile) for the sensor placement. The sensor is insulated and protected. Finally the vault is sealed and buried under ~30 cm of soil. The Flexible Array vault is provided to PIs by the EarthScope program, offering a uniform portable vault for these deployments. The vault consists of a 30 cm diameter by 0.75 cm tall piece of plastic sewage pipe buried with ~10 cm of pipe above grade. A rubber membrane covers the bottom and cement was poured into the bottom, coupling the pier to the pipe. The vault is sealed and buried under ~30 cm of soil. Cost, logistics, and the availability of materials in-country are usually the deciding factors for PIs when choosing a vault design and frequently trades are made given available resources. Recently a third type of portable broadband installation, direct burial, is being tested. In this case a sensor designed for shallow, direct burial is installed in a ~20 cm diameter by ~1 m deep posthole. Direct burial installation costs are limited to the time and effort required to dig the posthole and emplace the sensor. Our initial analyses suggest that direct burial sensors perform as well and at times better than sensor in vaults on both horizontal and vertical channels across a range of periods (<1 s to 100 s). Moving towards an instrument pool composed entirely of direct burial sensors (some with integrated digitizers) could yield higher-quality data at lower cost. Until recently vault performance for portable installations supported by the PASSCAL program was anecdotal. A formal comparison of these various installation techniques is the subject of this poster. We've selected a suite of experiments that are representative of the three installation techniques and compare their noise performance by using PSD probability density functions (McNamara and Buland, 2004).

  1. LSSA (Low-cost Silicon Solar Array) project

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Methods are explored for economically generating electrical power to meet future requirements. The Low-Cost Silicon Solar Array Project (LSSA) was established to reduce the price of solar arrays by improving manufacturing technology, adapting mass production techniques, and promoting user acceptance. The new manufacturing technology includes the consideration of new silicon refinement processes, silicon sheet growth techniques, encapsulants, and automated assembly production being developed under contract by industries and universities.

  2. Universal Design in Higher Education: From Principles to Practice

    ERIC Educational Resources Information Center

    Burgstahler, Sheryl E., Ed.; Cory, Rebecca C., Ed.

    2008-01-01

    "Universal Design in Higher Education" looks at the design of physical and technological environments at institutions of higher education; at issues pertaining to curriculum and instruction; and at the full array of student services. "Universal Design in Higher Education" is a comprehensive guide for researchers and…

  3. Semiarid ECohydrological Array – SECA 2058

    USDA-ARS?s Scientific Manuscript database

    The Southwestern ECohydrology Array (SECA) is a multi-user network that serves to assess biosphere / atmospheric exchange processes, as well as surface hydrology in semiarid ecosystems. SECA is administered through the USDA-ARS Southwest Watershed Research Center and the University of Arizona’s B2 E...

  4. Detector characterization, optimization, and operation for ACTPol

    NASA Astrophysics Data System (ADS)

    Grace, Emily Ann

    2016-01-01

    Measurements of the temperature anisotropies of the Cosmic Microwave Background (CMB) have provided the foundation for much of our current knowledge of cosmology. Observations of the polarization of the CMB have already begun to build on this foundation and promise to illuminate open cosmological questions regarding the first moments of the universe and the properties of dark energy. The primary CMB polarization signal contains the signature of early universe physics including the possible imprint of inflationary gravitational waves, while a secondary signal arises due to late-time interactions of CMB photons which encode information about the formation and evolution of structure in the universe. The Atacama Cosmology Telescope Polarimeter (ACTPol), located at an elevation of 5200 meters in Chile and currently in its third season of observing, is designed to probe these signals with measurements of the CMB in both temperature and polarization from arcminute to degree scales. To measure the faint CMB polarization signal, ACTPol employs large, kilo-pixel detector arrays of transition edge sensor (TES) bolometers, which are cooled to a 100 mK operating temperature with a dilution refrigerator. Three such arrays are currently deployed, two with sensitivity to 150 GHz radiation and one dichroic array with 90 GHz and 150 GHz sensitivity. The operation of these large, monolithic detector arrays presents a number of challenges for both assembly and characterization. This thesis describes the design and assembly of the ACTPol polarimeter arrays and outlines techniques for their rapid characterization. These methods are employed to optimize the design and operating conditions of the detectors, select wafers for deployment, and evaluate the baseline array performance. The results of the application of these techniques to wafers from all three ACTPol arrays is described, including discussion of the measured thermal properties and time constants. Finally, aspects of the characterization and calibration of the deployed detectors during field operations are discussed.

  5. Developing the Next Generation of Inspired and Enthusiastic Young African Scientists: Insights from the First Ten Years of AfricaArray

    NASA Astrophysics Data System (ADS)

    Manzi, M. S.; Webb, S. J.; Durrheim, R. J.; Gibson, R.

    2016-12-01

    The African continent is endowed with a wealth of resources that are the focus of vigorous exploration by international mining companies. However, it is unfortunate that many African countries have been unable to capitalize on resource development due to a lack of expertise in research, exploration, resource management and develop their mineral deposits. The capacity to develop natural resources in Africa is, inextricably linked to the ability to fully develop intellectual capacity. Thus, training young African geoscientists to investigate and manage Africa's natural resources, and developing scientific programs about Africa resources, their settings, controls and origins, should lie at the heart of all African universities. Ten years in to the AfricaArray program, it is worth reviewing some of the insights and successes we have gained. In Africa, there is a lack of knowledge of what a "scientist" is and University is often viewed as a continuation of high school. With no real exposure to research, students don't understand the huge difference between high school and university, and they treat the university as a high school. One way to mitigate this may be to include undergraduate research opportunities in the summer break but funding is difficult to allocate. This observation highlights the need to critically review our approach to research, teaching and learning, and social engagement at school level. At University level a key focus has been the development of capacity through international collaborative research and training. The School of Geosciences, at Wits University, is already the leading institution in Africa for its breadth of geosciences research and training, and the applied nature of its research, being ranked in the top 1% of institutions worldwide in its field. It is currently a lead partner in flagship international research geophysics programme focused on Africa - the AfricaArray Field School and AfricaArray Programme. Field school has spawned other developing field schools throughout Africa.

  6. The University of Florida's next-generation cryogenic infrared focal plane array controller system

    NASA Astrophysics Data System (ADS)

    Raines, Steven N.; Boreman, Glenn D.; Eikenberry, Stephen S.; Bandyopadhyay, Reba M.; Quijano, Ismael

    2008-07-01

    The Infrared Instrumentation Group at the University of Florida has substantial experience building IR focal plane array (FPA) controllers and seamlessly integrating them into the instruments that it builds for 8-meter class observatories, including writing device drivers for UNIX-based computer systems. We report on a design study to investigate implementing an ASIC from Teledyne Imaging Systems (TIS) into our IR FPA controller while simultaneously replacing TIS's interface card with one that eliminates the requirement for a Windows-OS computer within the instrument's control system.

  7. Assessment of undiscovered oil and gas resources of the Taoudeni Basin Province, Mali and Mauritania, 2015

    USGS Publications Warehouse

    Brownfield, Michael E.; Schenk, Christopher J.; Klett, Timothy R.; Tennyson, Marilyn E.; Pitman, Janet K.; Gaswirth, Stephanie B.; Le, Phuong A.; Leathers-Miller, Heidi M.; Mercier, Tracey J.; Marra, Kristen R.; Hawkins, Sarah J.

    2016-03-31

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated undiscovered, technically recoverable mean resources of 160 million barrels of conventional oil, 1,880 billion cubic feet of conventional gas, 602 million barrels of shale oil, and 6,395 billion cubic feet of shale gas in the Taoudeni Basin Province in Mali and Mauritania.

  8. Assessment of undiscovered oil and gas resources of the North Sakhalin Basin Province, Russia, 2011

    USGS Publications Warehouse

    Klett, T.R.; Schenk, Christopher J.; Wandrey, Craig J.; Charpentier, Ronald R.; Brownfield, Michael E.; Pitman, Janet K.; Pollastro, Richard M.; Cook, Troy A.; Tennyson, Marilyn E.

    2011-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated volumes of undiscovered, technically recoverable, conventional petroleum resources for the North Sakhalin Basin Province of Russia. The mean volumes were estimated at 5.3 billion barrels of crude oil, 43.8 trillion cubic feet of natural gas, and 0.8 billion barrels of natural gas liquids.

  9. An Electron-Diffraction Examination of Cast-Iron Piston Rings from Single-Cylinder Aircraft-Engine Tests

    DTIC Science & Technology

    1945-02-01

    found t; a great extent on thn ueed cylinder barrel ( SAE 4140 steel) and to a lesser extent on the top ohrmne- plated ring of the aesembl.yafter it had...on the used cylinder barrel (W 4140 steel) used in the tests and, to a lesser extent, on the used top chrome-platedring of the piston assembly. The

  10. The Barrel of the Gun and the Barrel of Oil in North-South Equation. Working Paper Number Five.

    ERIC Educational Resources Information Center

    Mazrui, Ali A.

    Current trends in armaments and militarism in the third world countries must be assessed against a background of imperialism and in relation to the tendency to use nuclear power for peaceful ends and oil power for militaristic ends. Discussion of these factors with relation to China, India, and the Arab countries requires examination of…

  11. Procedure for Near-Simultaneous Testing

    DTIC Science & Technology

    2006-12-01

    figure 8). A commercial handgun laser sight was fitted to a body that threaded on the breech end of each Mann barrel . After an initial test shot, the...Donald J. Little Weapons and Materials Research Directorate, ARL Approved for public...ANSI Std. Z39.18 Contents List of Figures iv 1. Introduction 1 2. Barrel Mounting 3 3. Target Fixturing 3 4. Electric Initiation 3 5. Gun

  12. Through-the-Wall Small Weapon Detection Based on Polarimetric Radar Techniques

    DTIC Science & Technology

    2009-12-01

    waves can penetrate through clothing (textile materials ), they have very poor penetration properties through many common construction materials (such...including the continuous metallic barrel ). Unless specified otherwise, the mesh has a resolution (cell size) of 2 mm. The wood dielectric constant...almost perpendicularly to the barrel ). Figure 2. Estimating the tilt angle of a cylindrical metallic rod of 1 m length

  13. Assessment of undiscovered oil and gas resources in Jurassic and Cretaceous strata of the Gulf Coast, 2010

    USGS Publications Warehouse

    Dubiel, Russell F.; Warwick, Peter D.; Swanson, Sharon; Burke, Lauri; Biewick, Laura; Charpentier, Ronald R.; Coleman, James L.; Cook, Troy A.; Dennen, Kris; Doolan, Colin A.; Enomoto, Catherine; Hackley, Paul C.; Karlsen, Alexander W.; Klett, Timothy R.; Kinney, Scott A.; Lewan, Michael D.; Merrill, Matt; Pearson, Krystal; Pearson, Ofori N.; Pitman, Janet K.; Pollastro, Richard M.; Rowan, Elizabeth L.; Schenk, Christopher J.; Valentine, Brett

    2011-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 147.4 trillion cubic feet of undiscovered natural gas, 2.4 billion barrels of undiscovered oil, and 2.96 billion barrels of undiscovered natural gas liquids in Jurassic and Cretaceous strata in onshore lands and State waters of the Gulf Coast.

  14. 40 CFR 73.90 - Allowance allocations for small diesel refineries.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Director, Acid Rain Division, under the procedures set forth in § 73.13 of this part. (c) Allowance... exceed 1500 for any calendar year: EC01SE92.092 where: a = diesel fuel in barrels for the year (or for October 1 through December 31 for 1993) b = lbs per barrel of diesel c = lbs of sulfur per lbs of diesel d...

  15. 40 CFR 73.90 - Allowance allocations for small diesel refineries.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Director, Acid Rain Division, under the procedures set forth in § 73.13 of this part. (c) Allowance... exceed 1500 for any calendar year: EC01SE92.092 where: a = diesel fuel in barrels for the year (or for October 1 through December 31 for 1993) b = lbs per barrel of diesel c = lbs of sulfur per lbs of diesel d...

  16. 40 CFR 73.90 - Allowance allocations for small diesel refineries.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Director, Acid Rain Division, under the procedures set forth in § 73.13 of this part. (c) Allowance... exceed 1500 for any calendar year: EC01SE92.092 where: a = diesel fuel in barrels for the year (or for October 1 through December 31 for 1993) b = lbs per barrel of diesel c = lbs of sulfur per lbs of diesel d...

  17. Homemade battery-operated multi-barreled muzzle-loading gun.

    PubMed

    Ramiah, R; Thirunavukkarasu, G

    2003-11-01

    In a recent shootout by a terrorist group against a law enforcement agency, some unusual firearms were seized. On examination, these firearms were found to be homemade, battery-operated, multi-barreled muzzle-loading guns, analogous to a repeater. Reference to battery-operated firearms is rather scanty in the literature. Hence, the unique design features, electrical circuit, and the operation system of these unusual guns are described.

  18. Assessment of Undiscovered Petroleum Resources of Southern and Western Afghanistan, 2009

    USGS Publications Warehouse

    Wandrey, C.J.; Kosti, Amir Zada; Selab, Amir Mohammad; Omari, Mohammad Karim; Muty, Salam Abdul; Nakshband, Haidari Gulam; Hosine, Abdul Aminulah; Wahab, Abdul; Hamidi, Abdul Wasy; Ahmadi, Nasim; Agena, Warren F.; Charpentier, Ronald R.; Cook, Troy; Drenth, B.J.

    2009-01-01

    Using a geology-based assessment methodology, the U.S. Geological Survey--Afghanistan Ministry of Mines Joint Oil and Gas Resource Assessment Team estimated mean undiscovered resource volumes of 21.55 million barrels of oil, 44.76 billion cubic feet of non-associated natural gas, and 0.91 million barrels of natural gas liquids in the western Afghanistan Tirpul Assessment Unit (AU) (80230101).

  19. Assessment of undiscovered shale gas and shale oil resources in the Mississippian Barnett Shale, Bend Arch–Fort Worth Basin Province, North-Central Texas

    USGS Publications Warehouse

    Marra, Kristen R.; Charpentier, Ronald R.; Schenk, Christopher J.; Lewan, Michael D.; Leathers-Miller, Heidi M.; Klett, Timothy R.; Gaswirth, Stephanie B.; Le, Phuong A.; Mercier, Tracey J.; Pitman, Janet K.; Tennyson, Marilyn E.

    2015-12-17

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated mean volumes of 53 trillion cubic feet of shale gas, 172 million barrels of shale oil, and 176 million barrels of natural gas liquids in the Barnett Shale of the Bend Arch–Fort Worth Basin Province of Texas.

  20. Assessment of undiscovered oil and gas resources in the Uteland Butte Member of the Eocene Green River Formation, Uinta Basin, Utah

    USGS Publications Warehouse

    Johnson, Ronald C.; Birdwell, Justin E.; Mercier, Tracey J.; Brownfield, Michael E.; Charpentier, Ronald R.; Klett, Timothy R.; Leathers, Heidi M.; Schenk, Christopher J.; Tennyson, Marilyn E.

    2015-09-03

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated mean undiscovered resources of 214 million barrels of oil, 329 billion cubic feet of associated/dissolved natural gas, and 14 million barrels of natural gas liquids in the informal Uteland Butte member of the Green River Formation, Uinta Basin, Utah.

  1. Chromium Elimination and Cannon Life Extension for Gun Tubes

    DTIC Science & Technology

    2012-08-30

    the use of hexavalent chromium (VI) in the production of cannon barrels by developing a cost effective environmentally friendly Explosive Bonding...erosion- resistant chrome cobalt alloy matrix with 15% tungsten. Stellite is used as M60 machine gun barrel liner. Tantalum Cobalt Tungsten...Grounds (YPG) Preliminary proof of principle endurance testing at YPG shows promising results when conducted side by side to a chrome plated

  2. Evaluating the Impact of the Fully Burdened Cost of Fuel

    DTIC Science & Technology

    2009-09-01

    174,864,115( ) AverageDFMCost DDG NumberDDGsCE CostOfFuel gal DestroyerDFMConsumed gal perDDG gal gal    (3.1) Underway Not Underway Auxillary Cost...DFM Underway 4,512,879 5,722,483 10,235,362 Barrels DFM Not Underway 438,907 518,164 957,071 Barrels DFM Auxillary 9,165 16,226 25,392 2008 DFM

  3. Go Grey - A Laundry to Landscape Irrigation System

    NASA Astrophysics Data System (ADS)

    Rajmohan, S.

    2017-12-01

    California residents have dealt with severe drought and high water bills for the few past years[1]. The objective of our project is to use the concept of greywater irrigation to build a low cost, adaptable, and easy to install irrigation system to collect the greywater from the washing machine and use it to water the plants. This system can reduce a household's water usage, extend the life of a septic system, and save time on watering plants by recycling the water from the washing machine. Our simple system requires PVC pipes, a three-way water diverter (valve), a mesh coffee filter, and a water (rain) barrel. The water from the washing machine travels through the three-way valve, which diverts it either to the garden or to the sewer. The PVC pipes lead outside to the garden, where the water barrel is located. The water goes through the mesh coffee filter that is attached on top of the barrel, so that lint and other impurities can be filtered out. The water collected in the barrel will travel through drip irrigation or through a hose to directly water the roots of the plants. This fully functional greywater system was successfully constructed and tested through various trails. We used a Kenmore standard 4.5 cubic feet front load high efficiency washer which uses less water compared to the traditional washers and measured the water collected in water barrel after each wash. Irrespective of the size of the load, the amount of water collected from each wash remained almost the same.. However, we collected enough grey water from each washer load to fill the rain barrel and water the plants in the garden. We were able apply the concept of greywater irrigation successfully to build our own low cost, adaptable, and easy to install greywater system that can be used in any household to water plants in the garden. Our system recycles the water from the washer instead of just wasting it thereby reducing a household's water usage and water bill especially during the time of drought. [1] U.S.Geological Survey/California Water Science Center - https://ca.water.usgs.gov/data/drought/index.html

  4. Sub- and suprathreshold receptive field properties of pyramidal neurones in layers 5A and 5B of rat somatosensory barrel cortex

    PubMed Central

    Manns, Ian D; Sakmann, Bert; Brecht, Michael

    2004-01-01

    Layer 5 (L5) pyramidal neurones constitute a major sub- and intracortical output of the somatosensory cortex. This layer 5 is segregated into layers 5A and 5B which receive and distribute relatively independent afferent and efferent pathways. We performed in vivo whole-cell recordings from L5 neurones of the somatosensory (barrel) cortex of urethane-anaesthetized rats (aged 27–31 days). By delivering 6 deg single whisker deflections, whisker pad receptive fields were mapped for 16 L5A and 11 L5B neurones located below the layer 4 whisker-barrels. Average resting membrane potentials were −75.6±1.1 mV, and spontaneous action potential (AP) rates were 0.54± 0.14 APs s−1. Principal whisker (PW) evoked responses were similar in L5A and L5B neurones, with an average 5.0 ± 0.6 mV postsynaptic potential (PSP) and 0.12 ± 0.03 APs per stimulus. The layer 5A sub- and suprathreshold receptive fields (RFs) were more confined to the principle whisker than those of layer 5B. The basal dendritic arbors of layer 5A and 5B cells were located below both layer 4 barrels and septa, and the cell bodies were biased towards the barrel walls. Responses in both L5A and L5B developed slowly, with onset latencies of 10.1 ± 0.5 ms and peak latencies of 33.9 ± 3.3 ms. Contralateral multi-whisker stimulation evoked PSPs similar in amplitude to those of PW deflections; whereas, ipsilateral stimulation evoked smaller and longer latency PSPs. We conclude that in L5 a whisker deflection is represented in two ways: focally by L5A pyramids and more diffusely by L5B pyramids as a result of combining different inputs from lemniscal and paralemniscal pathways. The relevant output evoked by a whisker deflection could be the ensemble activity in the anatomically defined cortical modules associated with a single or a few barrel-columns. PMID:14724202

  5. Analysis of entry of additional energy to gunpowder in electrothermal chemical shot

    NASA Astrophysics Data System (ADS)

    Burkin, Viktor; Ishchenko, Alexandr; Kasimov, Vladimir; Samorokova, Nina; Sidorov, Aleksey

    2017-11-01

    In the article two series of ballistic experiments conducted according to the scheme of electrothermal chemical control of ballistic parameters of the shot at the Research Institute of Applied Mathematics and Mechanics of Tomsk State University (RIAMM TSU, Russia) are considered. The experimental part of the work is described. The analysis of the electro physical data of ballistic experiments is carried out. A methodical approach that allows to take into account the entry of an electric discharge plasma in a gunpowder in the mathematical model of internal ballistic processes in barrel systems is proposed and tested. Under the conditions of these experiments, the effects of various characteristics of the plasmatron on the nature of the energy entry are estimated.

  6. Life cycle water demand coefficients for crude oil production from five North American locations.

    PubMed

    Ali, Babkir; Kumar, Amit

    2017-10-15

    The production of liquid fuels from crude oil requires water. There has been limited focus on the assessment of life cycle water demand footprints for crude oil production and refining. The overall aim of this paper is address this gap. The objective of this research is to develop water demand coefficients over the life cycle of fuels produced from crude oil pathways. Five crude oil fields were selected in the three North American countries to reflect the impact of different spatial locations and technologies on water demand. These include the Alaska North Slope, California's Kern County heavy oil, and Mars in the U.S.; Maya in Mexico; and Bow River heavy oil in Alberta, Canada. A boundary for an assessment of the life cycle water footprint was set to cover the unit operations related to exploration, drilling, extraction, and refining. The recovery technology used to extract crude oil is one of the key determining factors for water demand. The amount of produced water that is re-injected to recover the oil is essential in determining the amount of fresh water that will be required. During the complete life cycle of one barrel of conventional crude oil, 1.71-8.25 barrels of fresh water are consumed and 2.4-9.51 barrels of fresh water are withdrawn. The lowest coefficients are for Bow River heavy oil and the highest coefficients are for Maya crude oil. Of all the unit operations, exploration and drilling require the least fresh water (less than 0.015 barrel of water per barrel of oil produced). A sensitivity analysis was conducted and uncertainty in the estimates was determined. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Distortion of the temporary cavity and its influence on staining in firearm barrels.

    PubMed

    Schyma, Christian; Müller, Rolf; Brenčičová, Eva; Brünig, Julia

    2018-06-01

    After contact shots to the head, biological traces can be found inside the barrel of the firearm. Experimental protocols to generate this sort of staining, using 12 cm gelatin cubes containing thin foil bags filled with acrylic paint, human blood, and radiocontrast agent, have been developed. Previous research on shots fired at a distance has shown the underlay sustaining these gelatin cubes has an influence on experimental results. This study was conducted to investigate the role of the sustaining base of the gelatin blocks during contact shots, and its influence on the staining result inside firearm barrels. Eighteen contact shots were performed using 22 LR, 32 ACP (7.65 Browning) and 9 mm Luger semi-automatic pistols. With each pistol, shots were fired onto six gelatin cubes; three placed upon a rigid platform and three upon an elastic underlay. The shots were recorded by a high-speed video camera as they penetrated the gelatin cube. Any staining present inside the firearm barrels after the shots were fired was documented by endoscopy. Cross sections of the gelatin blocks were then compared to the high-speed video. It was found that the nature of the staining inside the barrel was not influenced by the underlay sustaining the target model. In the experiment using a 9 mm Luger, the rigid counterfort provoked a visible distortion of the temporary cavity, but, cross sectional analysis of the gelatin cubes did not reveal a relevant influence of the sustaining underlay on the crack length in the gelatin. This could be explained by a secondary expansion of the temporary cavity left by the projectile as a consequence of subsequent inflow of muzzle gases.

  8. Apparatus for and method of operating a cylindrical pulsed induction mass launcher

    DOEpatents

    Cowan, M. Jr.; Duggin, B.W.; Widner, M.M.

    1992-06-30

    An electromagnetic cylindrical projectile mass launcher and a method of operation is provided which includes a cylindrical projectile having a conducting armature, a cylindrical barrel in which the armature is received, a plurality of electromagnetic drive coil stages, a plurality of pulse energy sources, and a pulsed power arrangement for generating magnetic pulses forming a pulsed magnetic wave along the length of the launcher barrel. The pulsed magnetic wave provides a propelling force on the projectile along the drive coil. The pulsed magnetic wave of the drive coil stages is advanced along the armature faster than the projectile to thereby generate an induced current wave in the armature. The pulsed generation of the magnetic wave minimizes electromagnetic heating of the projectile and provides for smooth acceleration of the projectile through the barrel of the launcher. 2 figs.

  9. Apparatus for and method of operating a cylindrical pulsed induction mass launcher

    DOEpatents

    Cowan, Jr., Maynard; Duggin, Billy W.; Widner, Melvin M.

    1992-01-01

    An electromagnetic cylindrical projectile mass launcher and a method of operation is provided which includes a cylindrical projectile having a conducting armature, a cylindrical barrel in which the armature is received, a plurality of electromagnetic drive coil stages, a plurality of pulse energy sources, and a pulsed power arrangement for generating magnetic pulses forming a pulsed magnetic wave along the length of the launcher barrel. The pulsed magnetic wave provides a propelling force on the projectile along the drive coil. The pulsed magnetic wave of the drive coil stages is advanced along the armature faster than the projectile to thereby generate an induced current wave in the armature. The pulsed generation of the magnetic wave minimizes electromagnetic heating of the projectile and provides for smooth acceleration of the projectile through the barrel of the launcher.

  10. Correlation of Cooling Data from an Air-Cooled Cylinder and Several Multicylinder Engines

    NASA Technical Reports Server (NTRS)

    Pinkel, Benjamin; Ellerbrock, Herman H , Jr

    1940-01-01

    The theory of engine-cylinder cooling developed in a previous report was further substantiated by data obtained on a cylinder from a Wright r-1820-g engine. Equations are presented for the average head and barrel temperatures of this cylinder as functions of the engine and the cooling conditions. These equations are utilized to calculate the variation in cylinder temperature with altitude for level flight and climb. A method is presented for correlating average head and barrel temperatures and temperatures at individual points on the head and the barrel obtained on the test stand and in flight. The method is applied to the correlation and the comparison of data obtained on a number of service engines. Data are presented showing the variation of cylinder temperature with time when the power and the cooling pressure drop are suddenly changed.

  11. Man-in-the-barrel. A case of cervical spinal cord infarction and review of the literature.

    PubMed

    Antelo, María José García; Facal, Teresa Lema; Sánchez, Tamara Pablos; Facal, María Soledad López; Nazabal, Eduardo Rubio

    2013-01-01

    Man-in-the-barrel syndrome was initially observed in patients with signs of serious cerebral hypoperfusion, in the border zone of the anterior and medial cerebral artery, but other causes were communicated later. a healthy 43-year-old woman who showed intense cervical pain, irradiating over both shoulders and arms. Physical examination on admission highlighted notable brachial diparesis, tacto-algesic hypoesthesia of both arms and sensory level C4-D9. cervical Magnetic Resonance Imaging (MRI) on admission revealed a hyperintense intramedullar lesion at C3-C7 level, due to a cervical cord infarction. our case reveals that conventional neurological consideration about the specific anatomical location of man-in-the-barrel syndrome in the brain should be extended to other locations such as the cervical column and not only the brain area.

  12. Computational design of water-soluble α-helical barrels.

    PubMed

    Thomson, Andrew R; Wood, Christopher W; Burton, Antony J; Bartlett, Gail J; Sessions, Richard B; Brady, R Leo; Woolfson, Derek N

    2014-10-24

    The design of protein sequences that fold into prescribed de novo structures is challenging. General solutions to this problem require geometric descriptions of protein folds and methods to fit sequences to these. The α-helical coiled coils present a promising class of protein for this and offer considerable scope for exploring hitherto unseen structures. For α-helical barrels, which have more than four helices and accessible central channels, many of the possible structures remain unobserved. Here, we combine geometrical considerations, knowledge-based scoring, and atomistic modeling to facilitate the design of new channel-containing α-helical barrels. X-ray crystal structures of the resulting designs match predicted in silico models. Furthermore, the observed channels are chemically defined and have diameters related to oligomer state, which present routes to design protein function. Copyright © 2014, American Association for the Advancement of Science.

  13. The Internal Ballistics of an Air Gun

    NASA Astrophysics Data System (ADS)

    Denny, Mark

    2011-02-01

    The internal ballistics of a firearm or artillery piece considers the pellet, bullet, or shell motion while it is still inside the barrel. In general, deriving the muzzle speed of a gunpowder firearm from first principles is difficult because powder combustion is fast and it very rapidly raises the temperature of gas (generated by gunpowder deflagration, or burning), which greatly complicates the analysis. A simple case is provided by air guns, for which we can make reasonable approximations that permit a derivation of muzzle speed. It is perhaps surprising that muzzle speed depends upon barrel length (artillerymen debated this dependence for centuries, until it was established experimentally and, later, theoretically ). Here we see that a simple physical analysis, accessible to high school or freshmen undergraduate physics students, not only derives realistic muzzle speed but also shows how it depends upon barrel length.

  14. Assessment of undiscovered oil and gas resources of the North Caspian Basin, Middle Caspian Basin, North Ustyurt Basin, and South Caspian Basin Provinces, Caspian Sea Area, 2010

    USGS Publications Warehouse

    Klett, T.R.; Schenk, Christopher J.; Charpentier, Ronald R.; Gautier, Donald L.; Brownfield, Michael E.; Pitman, Janet K.; Cook, Troy A.; Tennyson, Marilyn E.

    2010-01-01

    The U.S. Geological Survey estimated mean volumes of technically recoverable, conventional, undiscovered petroleum resources at 19.6 billion barrels of crude oil, 243 trillion cubic feet of natural gas, and 9.3 billion barrels of natural gas liquids for the Caspian Sea area, using a geology-based assessment methodology.

  15. In-Place Oil Shale Resources Underlying Federal Lands in the Piceance Basin, Western Colorado

    USGS Publications Warehouse

    Mercier, Tracey J.; Johnson, Ronald C.; Brownfield, Michael E.; Self, Jesse G.

    2010-01-01

    Using a geologic-based assessment methodology, the U.S. Geological Survey estimated an in-place oil shale resource of 1.07 trillion barrels under Federal mineral rights, or 70 percent of the total oil shale in place, in the Piceance Basin, Colorado. More than 67 percent of the total oil shale in-place resource, or 1.027 trillion barrels, is under Federal surface management.

  16. NASA Marshall Space Flight Center Barrel-Shaped Asymmetrical Capacitor

    NASA Technical Reports Server (NTRS)

    Campbell, J. W.; Carruth, M. R.; Edwards, D. L.; Finchum, A.; Maxwell, G.; Nabors, S.; Smalley, L.; Huston, D.; Ila, D.; Zimmerman, R.

    2004-01-01

    The NASA Barrel-Shaped Asymmetrical Capacitor (NACAP) has been extensively tested at NASA Marshall Space Flight Center and the National Space Science and Technology Center. Trichel pulse emission was first discovered here. The NACAP is a magnetohydrodynamic device for electric propulsion. In air it requires no onboard propellant nor any moving parts. No performance was observed in hard vacuum. The next step shall be optimizing the technology for future applications.

  17. The Magic of Energy: Oil Surely Changed the Way that Humans Value Energy

    ERIC Educational Resources Information Center

    Deal, Walter F., III

    2005-01-01

    Recently, the price of gasoline seems to keep going up and up with seemingly no limit in sight. Accordingly, the price of a barrel of oil is in excess of sixty dollars today, when just a few years ago it was around twelve to fifteen dollars a barrel. There are many intertwined answers as to why the price of oil and gasoline are increasing.…

  18. Joint Armaments Conference, Exhibition and Firing Demonstration. Volume 1. Monday - Tuesday

    DTIC Science & Technology

    2010-05-20

    Grenade Launchers in China, Ms. Juanjuan Yang, China R&D Academy of Machinery · 10055 - K11, Dual- Barrel Air-Burst Weapon, Dr. In Woo Kim...an Advanced Lightweight Material , Mr. Christopher Still, ATK · 10170 - Case Weight Variation Reduction and Subsequent Ballistic Dispersion...10195 - Effects of Barrel Length on Sound Measurement, Bore Pressure, and Bullet Velocity, Dr. Philip Dater, Gemtech · 10186 - MEMS S&A

  19. U.S. Biodefense & Homeland Security: Toward Detection & Attribution

    DTIC Science & Technology

    2006-12-01

    Agency (EPA) and FBI hazardous material teams worked side-by-side, searching 280 barrels containing 635 bags of quarantined mail that had been...hazardous material teams searched 280 barrels containing 635 bags of quarantined mail that had been seized as evidence. The final letter was addressed to...Chapter IV. He provided important research material and fresh ideas based on his expertise as Scientist-in-Residence of the Center for

  20. The Essential β-Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis▿

    PubMed Central

    Rossiter, Amanda E.; Leyton, Denisse L.; Tveen-Jensen, Karina; Browning, Douglas F.; Sevastsyanovich, Yanina; Knowles, Timothy J.; Nichols, Katie B.; Cunningham, Adam F.; Overduin, Michael; Schembri, Mark A.; Henderson, Ian R.

    2011-01-01

    Autotransporter biogenesis is dependent upon BamA, a central component of the β-barrel assembly machinery (BAM) complex. In this report, we detail the role of the other BAM components (BamB-E). We identify the importance of BamD in autotransporter biogenesis and show that BamB, BamC, and BamE are not required. PMID:21665980

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