In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris

DOEpatents

Young, Travis; Schultz, Peter G.

2017-08-15

The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris. Methods for producing polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris are also provided.

In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris

DOEpatents

Young, Travis [San Diego, CA; Schultz, Peter G [La Jolla, CA

2014-02-11

The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methyltrophic yeast such as Pichia pastoris. Methods for producing polypeptides comprising unnatural amino acids in methyltrophic yeast such as Pichia pastoris are also provided.

Patterns and Limitations of Urban Human Mobility Resilience under the Influence of Multiple Types of Natural Disaster

PubMed Central

Wang, Qi; Taylor, John E.

2016-01-01

Natural disasters pose serious threats to large urban areas, therefore understanding and predicting human movements is critical for evaluating a population’s vulnerability and resilience and developing plans for disaster evacuation, response and relief. However, only limited research has been conducted into the effect of natural disasters on human mobility. This study examines how natural disasters influence human mobility patterns in urban populations using individuals’ movement data collected from Twitter. We selected fifteen destructive cases across five types of natural disaster and analyzed the human movement data before, during, and after each event, comparing the perturbed and steady state movement data. The results suggest that the power-law can describe human mobility in most cases and that human mobility patterns observed in steady states are often correlated with those in perturbed states, highlighting their inherent resilience. However, the quantitative analysis shows that this resilience has its limits and can fail in more powerful natural disasters. The findings from this study will deepen our understanding of the interaction between urban dwellers and civil infrastructure, improve our ability to predict human movement patterns during natural disasters, and facilitate contingency planning by policymakers. PMID:26820404

Patterns and Limitations of Urban Human Mobility Resilience under the Influence of Multiple Types of Natural Disaster.

PubMed

Wang, Qi; Taylor, John E

2016-01-01

Natural disasters pose serious threats to large urban areas, therefore understanding and predicting human movements is critical for evaluating a population's vulnerability and resilience and developing plans for disaster evacuation, response and relief. However, only limited research has been conducted into the effect of natural disasters on human mobility. This study examines how natural disasters influence human mobility patterns in urban populations using individuals' movement data collected from Twitter. We selected fifteen destructive cases across five types of natural disaster and analyzed the human movement data before, during, and after each event, comparing the perturbed and steady state movement data. The results suggest that the power-law can describe human mobility in most cases and that human mobility patterns observed in steady states are often correlated with those in perturbed states, highlighting their inherent resilience. However, the quantitative analysis shows that this resilience has its limits and can fail in more powerful natural disasters. The findings from this study will deepen our understanding of the interaction between urban dwellers and civil infrastructure, improve our ability to predict human movement patterns during natural disasters, and facilitate contingency planning by policymakers.

Interpretation of 'Unnatural death' in coronial law: A review of the English legal process of decision making, statutory interpretation, and case law: The implications for medical cases and coronial consistency.

PubMed

Harris, Andrew; Walker, Andrew

2018-04-23

The article examines the decision-making process for medical reporting of deaths to a coroner and the statutory basis for coronial decisions whether to investigate. It analyses what is published about the consistency of decision making of coroners and discusses what should be the legal basis for determining whether a particular death is natural or unnatural in English law. There is a review of English case law, including the significance of Touche and Benton and the development of 'unnatural' as a term of art, which informs what the courts have held to be an unnatural death. What case law indicates about multiple causes and the significance of the wording in the Coroners & Justice Act 2009 that triggers an investigation are considered. It highlights the importance of considering the medical cause of death and to what extent information other than the initial death report is required, before making the decision that the coroner's duty to open an investigation is triggered. The article concludes that a two-stage test is required. Firstly, is the cause of death medically unnatural? Secondly, whether the circumstances themselves are unnatural or such as to make a medically natural cause of death unnatural. If the coroner has reason to suspect the medical cause of death is unnatural per se the statutory duty to investigate will be engaged, regardless of the circumstances.

Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling

PubMed Central

Kasperkiewicz, Paulina; Poreba, Marcin; Snipas, Scott J.; Parker, Heather; Winterbourn, Christine C.; Salvesen, Guy S.; Drag, Marcin

2014-01-01

The exploration of protease substrate specificity is generally restricted to naturally occurring amino acids, limiting the degree of conformational space that can be surveyed. We substantially enhanced this by incorporating 102 unnatural amino acids to explore the S1–S4 pockets of human neutrophil elastase. This approach provides hybrid natural and unnatural amino acid sequences, and thus we termed it the Hybrid Combinatorial Substrate Library. Library results were validated by the synthesis of individual tetrapeptide substrates, with the optimal substrate demonstrating more than three orders of magnitude higher catalytic efficiency than commonly used substrates of elastase. This optimal substrate was converted to an activity-based probe that demonstrated high selectivity and revealed the specific presence of active elastase during the process of neutrophil extracellular trap formation. We propose that this approach can be successfully used for any type of endopeptidase to deliver high activity and selectivity in substrates and probes. PMID:24550277

Unnatural reactive amino acid genetic code additions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deiters, Alexander; Cropp, T. Ashton; Chin, Jason W.

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G.; Wang, Lei; Zhang, Zhiwen

2005-08-09

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G.; Wang, Lei; Zhang, Zhiwen

2010-11-16

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

2009-07-14

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G.; Wang, Lei; Zhang, Zhiwen

2006-10-31

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G [La Jolla, CA; Wang, Lei [San Diego, CA; Zhang, Zhiwen [San Diego, CA

2007-08-28

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G [La Jolla, CA; Wang, Lei [San Diego, CA; Zhang, Zhiwen [San Diego, CA

2007-07-03

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G.; Wang, Lei; Zhang, Zhiwen

2010-11-02

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G [La Jolla, CA; Wang, Lei [San Diego, CA; Zhang, Zhiwen [San Diego, CA

2007-05-15

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Schultz, Peter G.; Wang, Lei; Zhang, Zhiwen

2007-02-27

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Glycoprotein synthesis

DOEpatents

Shultz, Peter G [La Jolla, CA; Wang, Lei [San Diego, CA; Zhang, Zhiwen [San Diego, CA

2007-04-03

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.

Unnatural reactive amino acid genetic code additions

DOEpatents

Deiters, Alexander; Cropp, Ashton T; Chin, Jason W; Anderson, Christopher J; Schultz, Peter G

2013-05-21

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Unnatural reactive amino acid genetic code additions

DOEpatents

Deiters, Alexander [La Jolla, CA; Cropp, T Ashton [San Diego, CA; Chin, Jason W [Cambridge, GB; Anderson, J Christopher [San Francisco, CA; Schultz, Peter G [La Jolla, CA

2011-02-15

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Unnatural reactive amino acid genetic code additions

DOEpatents

Deiters, Alexander; Cropp, T. Ashton; Chin, Jason W.; Anderson, J. Christopher; Schultz, Peter G.

2014-08-26

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Unnatural reactive amino acid genetic code additions

DOEpatents

Deiters, Alexander [La Jolla, CA; Cropp, T Ashton [Bethesda, MD; Chin, Jason W [Cambridge, GB; Anderson, J Christopher [San Francisco, CA; Schultz, Peter G [La Jolla, CA

2011-08-09

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNAsyn-thetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Natural and technologic hazardous material releases during and after natural disasters: a review.

PubMed

Young, Stacy; Balluz, Lina; Malilay, Josephine

2004-04-25

Natural disasters may be powerful and prominent mechanisms of direct and indirect hazardous material (hazmat) releases. Hazardous materials that are released as the result of a technologic malfunction precipitated by a natural event are referred to as natural-technologic or na-tech events. Na-tech events pose unique environmental and human hazards. Disaster-associated hazardous material releases are of concern, given increases in population density and accelerating industrial development in areas subject to natural disasters. These trends increase the probability of catastrophic future disasters and the potential for mass human exposure to hazardous materials released during disasters. This systematic review summarizes direct and indirect disaster-associated releases, as well as environmental contamination and adverse human health effects that have resulted from natural disaster-related hazmat incidents. Thorough examination of historic disaster-related hazmat releases can be used to identify future threats and improve mitigation and prevention efforts.

Psychological Effects of Technological/Human-Caused Environmental Disasters: Examination of the Navajo and Uranium

ERIC Educational Resources Information Center

Markstrom, Carol A.; Charley, Perry H.

2003-01-01

Disasters can be defined as catastrophic events that challenge the normal range of human coping ability. The technological/human-caused disaster, a classification of interest in this article, is attributable to human error or misjudgment. Lower socioeconomic status and race intersect in the heightened risk for technological/human-caused disasters…

Development and Application of a Model of Fallout Shelter Stay Times.

DTIC Science & Technology

1978-12-29

post-attack environment is a disaster, and that human response to a nuclear disaster is an extropolation of human response to natural disasters...Soviet reaction to a nuclear disaster . This technique is not limited to fallout shelter studies. If an appropriate data base exists, subjects such as

Unnatural Deaths Among Children and Adolescents in Isfahan Province, Iran: A Forensic Epidemiology Study of Postmortem Data.

PubMed

Holakouie-Naieni, Kourosh; Koehler, Steven A; Karimi, Roya; Mardani, Fardin; Karimi, Jalal

2016-01-01

The issue of child and adolescent injury and violence is often absent from discussions and is largely invisible in public health policies. The purpose of this study was to describe the frequency and pattern of unnatural deaths during childhood and adolescence in Isfahan province in Iran. This retrospective, descriptive study involved unnatural deaths among individuals under the age of 20 years who died from unnatural causes as determined by a forensic autopsy at the Legal Medicine Center of Isfahan. During the study period, 8,010 unnatural deaths occurred, 1,222 of which were individuals under 20 years old. All 1,222 of these unnatural deaths were identified through autopsy. Among the 1,222 cases, 895 (73.2%) were male, and 327 were female (26.8%). Accidental deaths were found to be the most frequent manner of death comprising 1,029 (83.96%) cases, followed by suicide (120, 9.82%), undetermined cause of death (39, 3.19%), and homicide (9, 2.86%) cases. Road traffic accidents were the number 1 cause of death (597, 49%), followed by burns (122, 10%) and hanging (90, 7.4%). Injuries and violence that occur during childhood and adolescence represent a global public health problem, especially in low- and middle-income regions, and require urgent action.

Field Manual for Mental Health and Human Service Workers in Major Disasters.

ERIC Educational Resources Information Center

DeWolfe, Deborah J.

This field manual is intended for mental health workers and other human service providers who assist survivors following a disaster. It provides the basics of disaster mental health, with both specific and practical suggestions for workers. Essential information is included about disaster survivors' reactions and needs such as dealing with grief;…

Psychological effects of technological/human-caused environmental disasters: examination of the Navajo and uranium.

PubMed

Markstrom, Carol A; Charley, Perry H

2003-01-01

Disasters can be defined as catastrophic events that challenge the normal range of human coping ability. The technological/human-caused disaster, a classification of interest in this article, is attributable to human error or misjudgment. Lower socioeconomic status and race intersect in the heightened risk for technological/human-caused disasters among people of color. The experience of the Navajo with the uranium industry is argued to specifically be this type of a disaster with associated long-standing psychological impacts. The history of the Navajo with uranium mining and milling is reviewed with a discussion of the arduous efforts for compensation. The psychological impacts of this long-standing disaster among the Navajo are organized around major themes of: (a) human losses and bereavement, (b) environmental losses and contamination, (c) feelings of betrayal by government and mining and milling companies, (d) fears about current and future effects, (e) prolonged duration of psychological effects, (f) anxiety and depression, and (g) complicating factors of poverty and racism. The paper concludes with suggestions for culturally-appropriate education and intervention.

DARPA Robotics Challenge (DRC) Using Human-Machine Teamwork to Perform Disaster Response with a Humanoid Robot

DTIC Science & Technology

2017-02-01

DARPA ROBOTICS CHALLENGE (DRC) USING HUMAN-MACHINE TEAMWORK TO PERFORM DISASTER RESPONSE WITH A HUMANOID ROBOT FLORIDA INSTITUTE FOR HUMAN AND...AND SUBTITLE DARPA ROBOTICS CHALLENGE (DRC) USING HUMAN-MACHINE TEAMWORK TO PERFORM DISASTER RESPONSE WITH A HUMANOID ROBOT 5a. CONTRACT NUMBER...Human and Machine Cognition (IHMC) from 2012-2016 through three phases of the Defense Advanced Research Projects Agency (DARPA) Robotics Challenge

Preventing disasters: public health vulnerability reduction as a sustainable adaptation to climate change.

PubMed

Keim, Mark E

2011-06-01

Global warming could increase the number and severity of extreme weather events. These events are often known to result in public health disasters, but we can lessen the effects of these disasters. By addressing the factors that cause changes in climate, we can mitigate the effects of climate change. By addressing the factors that make society vulnerable to the effects of climate, we can adapt to climate change. To adapt to climate change, a comprehensive approach to disaster risk reduction has been proposed. By reducing human vulnerability to disasters, we can lessen--and at times even prevent--their impact. Human vulnerability is a complex phenomenon that comprises social, economic, health, and cultural factors. Because public health is uniquely placed at the community level, it has the opportunity to lessen human vulnerability to climate-related disasters. At the national and international level, a supportive policy environment can enable local adaptation to disaster events. The purpose of this article is to introduce the basic concept of disaster risk reduction so that it can be applied to preventing and mitigating the negative effects of climate change and to examine the role of community-focused public health as a means for lessening human vulnerability and, as a result, the overall risk of climate-related disasters.

Proposing a Universal Framework for Resilience: Optimizing Risk and Combating Human Vulnerabilities

NASA Astrophysics Data System (ADS)

Sarkar, Arunima

2017-04-01

In the recent years we have seen a massive impact of loss created to urban settlements and critical infrastructure as a result of disasters. The disaster risk associates itself vulnerabilities and many complexities which can disrupt the functioning of human society. The uncertain loss created by disasters can present unforeseeable risk which remain unaccounted to human understanding. It is imperative to note that human urbanization and development is correlated with human vulnerabilities and challenges posed by disasters. Disaster risks are aggravated by improper planning of cities, weak framework for urban governance and regulatory regimes and lack of equalities amongst the citizens. The international agenda on disaster risk reduction talks about increasing losses due to disasters associated with development and urbanization. The United Nations announced that the year 1990 was the International Decade for Natural Disaster Reduction. In relation to this, the "Yokohama Strategy and Plan of Action" was adopted at the first United Nations World Conference on Disaster Reduction. The United Nations Educational, Scientific and Cultural Organization's (UNESCO) Intergovernmental Oceanic Commission coordinated the World Conference on Disaster Reduction in 2005 where the Hyogo Framework for Action was adopted. The Hyogo Framework for Action: Building the resilience of communities to disaster was adopted by 168 nations after the massive loss caused by Indian ocean tsunami in 2005. The Hyogo Framework proposes to focus on implementation of risk and reliability system to shield disasters, proposes global scientific and community platform for disaster prevention and mitigation etc. The early warning system and its importance as an effective tool for reduction of human vulnerabilities for disaster management was majorly emphasized. It is imperative to highlight that resilience framework is important in order to minimize cost of disruption caused to critical infrastructure and to strengthen and optimize the decision making skill and platform for a better sustainable society. The resilience framework provides a cross-sector and multi-level analysis to tackle the vulnerabilities which can be caused to essential utilities like power, water, transport and various machineries that are essential for human sustainability. The direction of resilience framework focuses on prevention of damage and disruption of disaster, mitigate the loss caused to human society and provide the best response for disaster resilience. Thus, the basic pillars which are important for the implementation of resilience is proper governance framework and transparency which takes into account various cost and risk analysis. Thus a common and universal framework for resilience is the main requirement for mass accessibility. The aim of resilience framework focuses on universal adaptability, coherence and validation. A mixed method analysis has been undertaken in this research paper which focuses on the following issues: • Legal, Institutional and community framework for integrating resilience framework of global north and global south. • Spatial as well as statistical analysis to structuralize disaster risk and resilient framework for disaster management. • Early warning system and emergency response in a comparative scale to analyse the various models of risk and resilience framework implemented in USA, China, Nepal and India for proposing an integrated resilience strategy.

Himalayan/Karakoram Disaster After Disaster: The Pain Will Not Be Ending Anytime Soon

NASA Astrophysics Data System (ADS)

Kargel, J. S.; Leonard, G. J.

2013-12-01

Are recent natural disasters in the Himalaya/Karakoram partly human-caused? Will disasters diminish or increase in frequency? Natural disasters in this region are nothing new. Earthquakes, floods, landslides, avalanches, and debris flows have occurred in the Himalaya/Karakoram since the mountains first grew from the sea. Simply put, the Himalaya/Karakoram, being South Asia's 'water tower' and an active plate tectonic collision zone, must shed water and debris to the lowlands and the sea. When this activity occurs swiftly and with high intensity at or near human settlements, the results are often deadly. Remote sensing analysis of recent disasters coupled with demography, news accounts, and field studies indicate that there is a component of human responsibility. Two overarching human elements include (1) settlement and infrastructure encroachment into hazardous mountain areas and (2) aggravation of climate change. Both are substantially responsible--separately or together--for most of the recent tragedies. These conclusions provide the answer to when the disasters will end: not soon. Unfortunately, disasters will almost surely increase. Whether natural disasters have increased in frequency over the region's long historical record may be debated and must be researched. This expected link is a challenge to assess due to the stochastic nature of disasters and their triggering events (e.g., earthquakes and extreme weather events). While Himalayan tectonism, rock mechanics, glaciation, and climate are fundamental causes of the disasters, so are human land uses. Encroaching development into ever-hazardous zones is a paramount cause of much human tragedy. Climate change is harder to pin down specifically as a cause of some of these disasters, because some disasters are linked to rare extreme weather events and mass movements, which may be statistically but not individually attributable in part to climate change. Nevertheless, evidence supports a major role of climate change for some natural disasters, and little if any role in others. I select a few recent disaster examples (Attabad rockfall, Gayari avalanche, Seti River flood, and Uttarakhand floods) and summarize their relationships to geology and geomorphology, weather, climate change, habitation, and infrastructure development. Disasters are apt to increase in frequency, effects, and geographic spread due to increased habitation and infrastructure development and changing climate. Whether climate change causes glacier shrinkage or growth, glacier-related hazards are affected. Some of these disasters have international cross-cultural, political, economic, and security components and could spiral into further human catastrophes related to international tensions. Improved international cooperation could ease the chances for disasters to trigger additional unintended consequences between nations. Not all development and human uses of the Himalaya/Karakoram are unwise. Furthermore, some people committed to living in risky places have nowhere else to go. Climate change and shifting mountain processes may have winners and losers. All current and future uses of the region should be weighed against the rapidly changing climate and shifting natural hazard landscape. Acknowledgements: Support from NASA/USAID SERVIR Applied Science Team, NASA Science of Terra & Aqua, and USAID Climbers' Science.

SMM-chemokines: a class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development.

PubMed

Kumar, Santosh; Choi, Won-Tak; Dong, Chang-Zhi; Madani, Navid; Tian, Shaomin; Liu, Dongxiang; Wang, Youli; Pesavento, James; Wang, Jun; Fan, Xuejun; Yuan, Jian; Fritzsche, Wayne R; An, Jing; Sodroski, Joseph G; Richman, Douglas D; Huang, Ziwei

2006-01-01

Chemokines and their receptors play important roles in numerous physiological and pathological processes. To develop natural chemokines into receptor probes and inhibitors of pathological processes, the lack of chemokine-receptor selectivity must be overcome. Here, we apply chemical synthesis and the concept of modular modifications to generate unnatural synthetically and modularly modified (SMM)-chemokines that have high receptor selectivity and affinity, and reduced toxicity. A proof of the concept was shown by transforming the nonselective viral macrophage inflammatory protein-II into new analogs with enhanced selectivity and potency for CXCR4 or CCR5, two principal coreceptors for human immunodeficiency virus (HIV)-1 entry. These new analogs provided insights into receptor binding and signaling mechanisms and acted as potent HIV-1 inhibitors. These results support the concept of SMM-chemokines for studying and controlling the function of other chemokine receptors.

Building human resilience: the role of public health preparedness and response as an adaptation to climate change.

PubMed

Keim, Mark E

2008-11-01

Global climate change will increase the probability of extreme weather events, including heatwaves, drought, wildfire, cyclones, and heavy precipitation that could cause floods and landslides. Such events create significant public health needs that can exceed local capacity to respond, resulting in excess morbidity or mortality and in the declaration of disasters. Human vulnerability to any disaster is a complex phenomenon with social, economic, health, and cultural dimensions. Vulnerability to natural disasters has two sides: the degree of exposure to dangerous hazards (susceptibility) and the capacity to cope with or recover from disaster consequences (resilience). Vulnerability reduction programs reduce susceptibility and increase resilience. Susceptibility to disasters is reduced largely by prevention and mitigation of emergencies. Emergency preparedness and response and recovery activities--including those that address climate change--increase disaster resilience. Because adaptation must occur at the community level, local public health agencies are uniquely placed to build human resilience to climate-related disasters. This article discusses the role of public health in reducing human vulnerability to climate change within the context of select examples for emergency preparedness and response.

An expanded genetic code in mammalian cells with a functional quadruplet codon.

PubMed

Niu, Wei; Schultz, Peter G; Guo, Jiantao

2013-07-19

We have utilized in vitro evolution to identify tRNA variants with significantly enhanced activity for the incorporation of unnatural amino acids into proteins in response to a quadruplet codon in both bacterial and mammalian cells. This approach will facilitate the creation of an optimized and standardized system for the genetic incorporation of unnatural amino acids using quadruplet codons, which will allow the biosynthesis of biopolymers that contain multiple unnatural building blocks.

Orthogonal translation components for the in vivo incorporation of unnatural amino acids

DOEpatents

Schultz, Peter G.; Alfonta, Lital; Chittuluru, Johnathan R.; Deiters, Alexander; Groff, Dan; Summerer, Daniel; Tsao, Meng -Lin; Wang, Jiangyun; Wu, Ning; Xie, Jianming; Zeng, Huaqiang; Seyedsayamdost, Mohammad; Turner, James

2015-08-11

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetase that can incorporate unnatural amino acid into proteins produced in eubacterial host cells such as E. coli, or in a eukaryotic host such as a yeast cell. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing unnatural amino acids, and translation systems.

Orthogonal translation components for the in vivo incorporation of unnatural amino acids

DOEpatents

Schultz, Peter G.; Xie, Jianming; Zeng, Huaqiang

2012-07-10

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids into proteins produced in eubacterial host cells such as E. coli, or in a eukaryotic host such as a yeast cell. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing unnatural amino acids, and translation systems.

Stealth and Natural Disasters: Science, Policy and Human Behavior

NASA Astrophysics Data System (ADS)

Kieffer, S. W.

2008-12-01

Geophysicists, earth scientists, and other natural scientists play a key role in studying disasters, and are challenged to convey the science to the public and policy makers (including government and business). I have found it useful to introduce the concept of two general types of disasters to these audiences: natural and stealth. Natural disasters are geological phenomena over which we humans have some, but relatively little, control. Earthquakes, tsunamis, floods and volcanic eruptions are the most familiar examples, but exogenous events such as meteorite impacts, solar flares, and supernovae are also possibly disruptive. Natural disasters typically have an abrupt onset, cause immediate major change, are familiar from the historic record, and get much media and public attention. They cannot be prevented, but preplanning can ameliorate their effects. Natural disasters are increasingly amplified by us (humans), and we are increasingly affected by them due to our expanding presence on the planet. Less familiar disasters are unfolding in the near-term, but they are not happening in the minds of most people. They are approaching us stealthily, and for this reason I propose that we call them stealth disasters. They differ from natural disasters in several important ways: stealth disasters are primarily caused by, or driven by, the interaction of humans with complex cycles of processes on the planet. Examples are: fresh water shortages and contamination, soil degradation and loss, climate changes, ocean degradation. The onset of stealth disasters is incremental rather than abrupt. They may not unfold significantly during the course of one term of political office, but they are unfolding in our lifetime. We as individuals may or may not escape their consequences, but they will affect our children and grandchildren. If humans are familiar with stealth disasters at all, it is from a relatively local experience, e.g., flooding of the Mississippi or the Dust Bowl in the U.S., or their counterparts in other places globally. Knowledge of stealth disasters is not universal at the scale now required for global attention. Pre-planning can allay the impacts of stealth disasters, or possibly even prevent them. It is imperative that a new Congress and new Administration be informed of the need to respond to both the near-term natural disasters, and to immediately institute thoughtful planning to ally or prevent the stealth disasters.

Disaster Impacts on Human Capital Accumulation Shown in the Typhoon Haiyan Case

NASA Astrophysics Data System (ADS)

Özceylan Aubrecht, Dilek; Aubrecht, Christoph

2014-05-01

School children and their school environment are increasingly exposed to all kinds of hazards. Many disaster events have shown the extent of disaster impacts on the education sector which this study also highlights in the Typhoon Haiyan Case. Disasters do not only cause loss of lives or damage to educational facilities, they also entail significant economic and social consequences on human capital development in the short and long-run. While the trend of short term disaster impact can easily be analyzed in rapid post disaster assessments taking destroyed assets as proxy, usually analyses of medium and long-term effects of disasters include large inherent uncertainties and are of less tangible nature, require more time and complex methods and can often not give comprehensive results. The consequences of disasters especially in developing countries are therefore to a certain extent often left unknown. Generally, economic and social effects of disasters on human capital seem to be ambiguous and to some degree these effects are related to economic, social and institutional well-being. Thus, clear understanding is crucial to interpret its complex effects on human capital accumulation. This essential nature of medium and long-term effects has not been reflected in many analyses. Focus has mostly been given on the extent of physical damage, displacements, lives and assets lost instead of targeting resilience of social and economic characteristics of communities in terms of preventing human capital accumulation disruption. Main objective of this study is to provide a conceptual framework illustrating the impacts of disasters on schooling which might help in assessing such effects, as one of the fundamental components of human capital accumulation (Ozceylan Aubrecht, 2013). The dimensions of human capital building and its relationship to disasters under the light of past disaster events are discussed with a special focus on the recent Typhoon Haiyan that struck the Philippines in November 2013. Natural disasters adversely affect human capital accumulation in several ways including loss of life, damage to the educational system, decreased educational quality, increased child labor, and associated high dropout rates. Another dimension closely related to the human capital is the reduced economic strength of families that can limit the expenditures on well-being, including education, health and food (child malnutrition) (Baez et al., 2010; Cuaresma, 2010). According to information provided by UN and international media approximately 6 million children were affected by Typhoon Haiyan with 1.4 million homes of children and their families destroyed and 1.8 million children displaced. About 90% of the school buildings in the affected region were damaged and schools therefore stayed closed for up to 2 months causing disruption for more than a million pupils and 34,000 teachers. In some areas, when school returned to operation, only half of the school kids reported back. Also for the other pupils the situation was still challenging with many of the prior basic educational resources affected (destroyed textbooks and learning material, damaged classrooms) and no own equipment available (books, pens, etc.). Those reported impacts have already interrupted the educational continuity and it is expected to further continue by adversely affecting human capital accumulation in the longer term. Part of this work has been done under the Global Program for Safer Schools (GPSS) carried out at the Global Facility for Disaster Reduction and Recovery (GFDRR). References: Baez, J., A. de la Fuente, and I. Carlos, 2010. Do Natural Disasters Affect Human Capital? An Assessment Based on Existing Empirical Evidence. IZA Discussion Paper Series: 5164. Cuaresma, J., 2010. Natural Disasters and Human Capital Accumulation. World Bank Economic Review 24(2): 280-302. Ozceylan Aubrecht, D., 2013. Economic Impact of Disasters on the Education Sector. Global Program for Safer Schools (GPSS), GFDRR & The World Bank, Working Paper, Washington DC, August 2013, 30 pp.

Protein Design Using Unnatural Amino Acids

NASA Astrophysics Data System (ADS)

Bilgiçer, Basar; Kumar, Krishna

2003-11-01

With the increasing availability of whole organism genome sequences, understanding protein structure and function is of capital importance. Recent developments in the methodology of incorporation of unnatural amino acids into proteins allow the exploration of proteins at a very detailed level. Furthermore, de novo design of novel protein structures and function is feasible with unprecedented sophistication. Using examples from the literature, this article describes the available methods for unnatural amino acid incorporation and highlights some recent applications including the design of hyperstable protein folds.

On civil engineering disasters and their mitigation

NASA Astrophysics Data System (ADS)

Xie, Lili; Qu, Zhe

2018-01-01

Civil engineering works such as buildings and infrastructure are the carriers of human civilization. They are, however, also the origins of various types of disasters, which are referred to in this paper as civil engineering disasters. This paper presents the concept of civil engineering disasters, their characteristics, classification, causes, and mitigation technologies. Civil engineering disasters are caused primarily by civil engineering defects, which are usually attributed to improper selection of construction site, hazard assessment, design and construction, occupancy, and maintenance. From this viewpoint, many so-called natural disasters such as earthquakes, strong winds, floods, landslides, and debris flows are substantially due to civil engineering defects rather than the actual natural hazards. Civil engineering disasters occur frequently and globally and are the most closely related to human beings among all disasters. This paper emphasizes that such disasters can be mitigated mainly through civil engineering measures, and outlines the related objectives and scientific and technological challenges.

The American print news media 'construction' of five natural disasters.

PubMed

Ploughman, P

1995-12-01

In 1985, five international 'natural' disasters received prominent print news media coverage in the United States. Content analyses of selected print news media accounts of these five disasters were conducted. The purported evidence of alleged cause-effect relationships describing and explaining these disasters as 'objective' realities was evaluated in the light of the subjective selection of explanatory factors, themes, frameworks, and value assumptions which underlie the media's analysis and 'construction' of these events as 'natural' disasters. Analysis of the American print news media coverage of these disasters indicated an emphasis upon the dramatic, descriptive, climatological or geological qualities of these events rather than upon causal explanations emphasizing the role of human acts or omissions in the development of these disasters. The print news media 'constructed' these events as 'natural' disasters despite clear evidence of their hybrid, natural-human origins.

Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry

PubMed Central

Witte, Martin D.; Theile, Chris; Wu, Tongfei; Guimaraes, Carla P.; Blom, Annet E. M.; Ploegh, Hidde L.

2014-01-01

Chimeric proteins, including bi-specific antibodies, are biological tools with therapeutic applications. Genetic fusion and ligation methods allow the creation of N-to-C and C-toN fused recombinant proteins, but not the majority of non-template encoded fusions. The present protocol describes a simple procedure for the production of unnaturally linked N-to-N and C-to-C chimeric proteins. Equipping the N-terminus or C-terminus of the proteins of interest with a set of click handles using sortase A, followed by a click reaction, establishes unnatural N-to-N and C-to-C (hetero)dimer linked fusions. If the peptides, sortase A, and the proteins of interest are in hand, the unnaturally fused proteins can be obtained in 3–4 days. PMID:23989675

In Vitro Biosynthesis of Unnatural Enterocin and Wailupemycin Polyketides¥

PubMed Central

Kalaitzis, John A.; Cheng, Qian; Thomas, Paul M.; Kelleher, Neil L.; Moore, Bradley S.

2009-01-01

Nature has evolved finely tuned strategies to synthesize rare and complex natural products such as the enterocin family of polyketides from the marine bacterium Streptomyces maritimus. Herein we report the directed ex vivo multienzyme syntheses of 24 unnatural 5-deoxyenterocin and wailupemycin F and G analogues, 18 of which are new. We have generated molecular diversity by priming the enterocin biosynthesis enzymes with unnatural substrates and have illustrated further the uniqueness of this type II polyketide synthase by way of exploiting its unusual starter unit biosynthesis pathways. PMID:19215142

In vitro biosynthesis of unnatural enterocin and wailupemycin polyketides.

PubMed

Kalaitzis, John A; Cheng, Qian; Thomas, Paul M; Kelleher, Neil L; Moore, Bradley S

2009-03-27

Nature has evolved finely tuned strategies to synthesize rare and complex natural products such as the enterocin family of polyketides from the marine bacterium Streptomyces maritimus. Herein we report the directed ex vivo multienzyme syntheses of 24 unnatural 5-deoxyenterocin and wailupemycin F and G analogues, 18 of which are new. We have generated molecular diversity by priming the enterocin biosynthesis enzymes with unnatural substrates and have illustrated further the uniqueness of this type II polyketide synthase by way of exploiting its unusual starter unit biosynthesis pathways.

Holistic Approach to Disaster Management for a Sustainable Future

ERIC Educational Resources Information Center

Nath, Baiju K.

2006-01-01

Disasters are becoming the key concern of many nations. The term disaster usually meant for natural calamities. There of course may be a human hand behind each of the disasters, whether its' impact is small or large. Disasters can be categorized into natural and man made. In the case of natural disasters there may be some natural indicators to…

Site-specific incorporation of probes into RNA polymerase by unnatural-amino-acid mutagenesis and Staudinger-Bertozzi ligation

PubMed Central

Chakraborty, Anirban; Mazumder, Abhishek; Lin, Miaoxin; Hasemeyer, Adam; Xu, Qumiao; Wang, Dongye; Ebright, Yon W.; Ebright, Richard H.

2015-01-01

Summary A three-step procedure comprising (i) unnatural-amino-acid mutagenesis with 4-azido-phenylalanine, (ii) Staudinger-Bertozzi ligation with a probe-phosphine derivative, and (iii) in vitro reconstitution of RNA polymerase (RNAP) enables the efficient site-specific incorporation of a fluorescent probe, a spin label, a crosslinking agent, a cleaving agent, an affinity tag, or any other biochemical or biophysical probe, at any site of interest in RNAP. Straightforward extensions of the procedure enable the efficient site-specific incorporation of two or more different probes in two or more different subunits of RNAP. We present protocols for synthesis of probe-phosphine derivatives, preparation of RNAP subunits and the transcription initiation factor σ, unnatural amino acid mutagenesis of RNAP subunits and σ, Staudinger ligation with unnatural-amino-acid-containing RNAP subunits and σ, quantitation of labelling efficiency and labelling specificity, and reconstitution of RNAP. PMID:25665560

What constitutes a natural fire regime? Insight from the ecology and distribution of coniferous forest birds in North America

Treesearch

Richard L. Hutto; Courtney J. Conway; Victoria A. Saab; Jeffrey R. Walters

2008-01-01

Bird species that specialize in the use of burned forest conditions can provide insight into the prehistoric fire regimes associated with the forest types that they have occupied over evolutionary time. The nature of their adaptations reflects the specific post-fire conditions that occurred prior to the unnatural influence of humans after European settlement....

The use of an "unnatural" prostaglandin in the termination of pregnancy.

PubMed

Gillespie, A; Beazley, J M; van Dorp, D A

1971-04-01

An unnatural prostaglandin (PG) (prepared by biosynthesis using the method described by Vonkerman et al.) was used to terminate midtrimester pregnancy in 3 primiparous patients aged 21-24. The PG was administered intravenously using a Palmer slow infusion pump. The patients were monitored continuously with particular attention given to pulse, respiration, blood pressure, uterine contractions and cervical dilatation. All 3 cases successfully aborted. Effective infusion rate was similar to that of PGE1 and PGE2 (5-6 mcg/minute) and side effects were trivial (minimal skin flushing, vomiting, mild urticarial reaction). 2 of the patients aborted 8 and 22 hours after infusion stopped without being conscious of continuing uterine activity; the 3rd patient necessitated infusion on the 2nd day and exhibited increased response to the infusion; however, the PG supply was exhausted and syntocinon infusion facilitated the complete abortion. This study shows that this synthetic prostaglandin containing an uneven number of carbon atoms is pharmacologically active and can induce contractions in the intact human pregnant uterus.

The meaning of "natural": process more important than content.

PubMed

Rozin, Paul

2005-08-01

The meaning of the desirable attribute "natural" was explored in two samples, American college students and adults in the Philadelphia jury pool. Participants rated the naturalness of a variety of "natural" entities, before and after they were transformed by operations such as freezing, adding or removing components, mixing with other natural or unnatural entities, domestication, and genetic engineering. Results support four hypotheses. First, the principle of contagion accounts for many aspects of the reduction of naturalness by contact with unnatural entities. Second, chemical transformations reduce naturalness much more than physical transformations do. Third, the history of an entity's processing is more important in determining its naturalness than is the nature of the entity's contents. Fourth, mixing like natural entities (e.g., water from different sources) does not markedly reduce naturalness. The insertion of a gene from another species, the process used in producing genetically modified organisms, produces the biggest drop in naturalness; domestication, a human-accomplished activity that changes genotype and phenotype in major ways, is considered much less damaging to naturalness.

Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates

PubMed Central

Poreba, M; Kasperkiewicz, P; Snipas, S J; Fasci, D; Salvesen, G S; Drag, M

2014-01-01

Traditional combinatorial peptidyl substrate library approaches generally utilize natural amino acids, limiting the usefulness of this tool in generating selective substrates for proteases that share similar substrate specificity profiles. To address this limitation, we synthesized a Hybrid Combinatorial Substrate Library (HyCoSuL) with the general formula of Ac-P4-P3-P2-Asp-ACC, testing the approach on a family of closely related proteases – the human caspases. The power of this library for caspase discrimination extends far beyond traditional PS-SCL approach, as in addition to 19 natural amino acids we also used 110 diverse unnatural amino acids that can more extensively explore the chemical space represented by caspase-active sites. Using this approach we identified and employed peptide-based substrates that provided excellent discrimination between individual caspases, allowing us to simultaneously resolve the individual contribution of the apical caspase-9 and the executioner caspase-3 and caspase-7 in the development of cytochrome-c-dependent apoptosis for the first time. PMID:24832467

Call to Action: The Case for Advancing Disaster Nursing Education in the United States.

PubMed

Veenema, Tener Goodwin; Lavin, Roberta Proffitt; Griffin, Anne; Gable, Alicia R; Couig, Mary Pat; Dobalian, Aram

2017-11-01

Climate change, human conflict, and emerging infectious diseases are inexorable actors in our rapidly evolving healthcare landscape that are triggering an ever-increasing number of disaster events. A global nursing workforce is needed that possesses the knowledge, skills, and abilities to respond to any disaster or large-scale public health emergency in a timely and appropriate manner. The purpose of this article is to articulate a compelling mandate for the advancement of disaster nursing education within the United States with clear action steps in order to contribute to the achievement of this vision. A national panel of invited disaster nursing experts was convened through a series of monthly semistructured conference calls to work collectively towards the achievement of a national agenda for the future of disaster nursing education. National nursing education experts have developed consensus recommendations for the advancement of disaster nursing education in the United States. This article proposes next steps and action items to achieve the desired vision of national nurse readiness. Novel action steps for expanding disaster educational opportunities across the continuum of nursing are proposed in response to the current compelling need to prepare for, respond to, and mitigate the impact of disasters on human health. U.S. educational institutions and health and human service organizations that employ nurses must commit to increasing access to a variety of quality disaster-related educational programs for nurses and nurse leaders. Opportunities exist to strengthen disaster readiness and enhance national health security by expanding educational programming and training for nurses. © 2017 Sigma Theta Tau International.

Interdisciplinary Environmental-health Science Throughout Disaster Lifecycles

NASA Astrophysics Data System (ADS)

Plumlee, G. S.; Morman, S. A.; Hoefen, T. M.

2014-12-01

Potential human health effects from exposures to hazardous disaster materials and environmental contamination are common concerns following disasters. Using several examples from US Geological Survey environmental disaster responses (e.g., 2001 World Trade Center, mine tailings spills, 2005 Hurricane Katrina, 2007-2013 wildfires, 2011 Gulf oil spill, 2012 Hurricane Sandy, 2013 Colorado floods) and disaster scenarios (2011 ARkStorm, 2013 SAFRR tsunami) this presentation will illustrate the role for collaborative earth, environmental, and health science throughout disaster lifecycles. Pre-disaster environmental baseline measurements are needed to help understand environmental influences on pre-disaster health baselines, and to constrain the magnitude of a disaster's impacts. During and following disasters, there is a need for interdisciplinary rapid-response and longer-term assessments that: sample and characterize the physical, chemical, and microbial makeup of complex materials generated by the disasters; fingerprint material sources; monitor, map, and model dispersal and evolution of disaster materials in the environment; help understand how the materials are modified by environmental processes; and, identify key characteristics and processes that influence the exposures and toxicity of disaster materials to humans and the living environment. This information helps emergency responders, public health experts, and cleanup managers: 1) identify short- and long-term exposures to disaster materials that may affect health; 2) prioritize areas for cleanup; and 3) develop appropriate disposal solutions or restoration uses for disaster materials. By integrating lessons learned from past disasters with geospatial information on vulnerable sources of natural or anthropogenic contaminants, the environmental health implications of looming disasters or disaster scenarios can be better anticipated, which helps enhance preparedness and resilience. Understanding economic costs of environmental cleanup and environmental-health impacts from disasters is an area of needed research. Throughout all disaster stages, effective communication between diverse scientific disciplines and stakeholder groups is both a necessity and a challenge.

Rapid and scalable synthesis of innovative unnatural α,β or γ-amino acids functionalized with tertiary amines on their side-chains.

PubMed

Schneider, Séverine; Ftouni, Hussein; Niu, Songlin; Schmitt, Martine; Simonin, Frédéric; Bihel, Frédéric

2015-07-07

We report a selective ruthenium catalyzed reduction of tertiary amides on the side chain of Fmoc-Gln-OtBu derivatives, leading to innovative unnatural α,β or γ-amino acids functionalized with tertiary amines. Rapid and scalable, this process allowed us to build a library of basic unnatural amino acids at the gram-scale and directly usable for liquid- or solid-phase peptide synthesis. The diversity of available tertiary amines allows us to modulate the physicochemical properties of the resulting amino acids, such as basicity or hydrophobicity.

Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine

DOEpatents

Wang, Jiangyun; Schultz, Peter G.

2013-03-12

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetase that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel sythetases molecules, methods for identifying and making the novel synthetases, methods for producing containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lapidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.

Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine

DOEpatents

Wang, Jiangyun; Schultz, Peter G.

2010-09-07

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel synthetase molecules, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lipidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.

Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine

DOEpatents

Wang, Jiangyun; Schultz, Peter G.

2012-07-10

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel synthetase molecules, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lipidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.

Information and communication technology: connecting the public and first responders during disasters.

PubMed

Buzzelli, Michelle M; Morgan, Paula; Muschek, Alexander G; Macgregor-Skinner, Gavin

2014-01-01

Lack of success in disaster recovery occurs for many reasons, with one predominant catalyst for catastrophic failure being flawed and inefficient communication systems. Increased occurrences of devastating environmental hazards and human-caused disasters will continue to promulgate throughout the United States and around the globe as a result of the continuous intensive urbanization forcing human population into more concentrated and interconnected societies. With the rapid evolutions in technology and the advent of Information and communication technology (ICT) interfaces such as Facebook, Twitter, Flickr, Myspace, and Smartphone technology, communication is no longer a unidirectional source of information traveling from the newsroom to the public. In the event of a disaster, time critical information can be exchanged to and from any person or organization simultaneously with the capability to receive feedback. A literature review of current information regarding the use of ICT as information infrastructures in disaster management during human-caused and natural disasters will be conducted. This article asserts that the integrated use of ICTs as multidirectional information sharing tools throughout the disaster cycle will increase a community's resiliency and supplement the capabilities of first responders and emergency management officials by providing real-time updates and information needed to assist and recover from a disaster.

Promoting a culture of disaster preparedness.

PubMed

Medina, Angeli

2016-01-01

Disasters from all hazards, ranging from natural disasters, human-induced disasters, effects of climate change to social conflicts can significantly affect the healthcare system and community. This requires a paradigm shift from a reactive approach to a disaster risk management 'all-hazards' approach. Disaster management is a joint effort of the city, state, regional, national, multi-agencies and international organisations that requires effective communication, collaboration and coordination. This paper offers lessons learned and best practices, which, when taken into consideration, can strengthen the phases of disaster risk management.

A modular synthesis of dithiocarbamate pendant unnatural α-amino acids

EPA Science Inventory

Unnatural α-amino acids containing dithiocarbamate side chains were synthesized by a one-pot reaction of in-situ generated dithiocarbamate anions with sulfamidates. A wide range of these anions participated in the highly regio- and stereo-selective ring opening of sulfamidates to...

Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry.

PubMed

Witte, Martin D; Theile, Christopher S; Wu, Tongfei; Guimaraes, Carla P; Blom, Annet E M; Ploegh, Hidde L

2013-09-01

Chimeric proteins, including bispecific antibodies, are biological tools with therapeutic applications. Genetic fusion and ligation methods allow the creation of N-to-C and C-to-N fused recombinant proteins, but not unnaturally linked N-to-N and C-to-C fusion proteins. This protocol describes a simple procedure for the production of such chimeric proteins, starting from correctly folded proteins and readily available peptides. By equipping the N terminus or C terminus of the proteins of interest with a set of click handles using sortase A, followed by a strain-promoted click reaction, unnatural N-to-N and C-to-C linked (hetero) fusion proteins are established. Examples of proteins that have been conjugated via this method include interleukin-2, interferon-α, ubiquitin, antibodies and several single-domain antibodies. If the peptides, sortase A and the proteins of interest are in hand, the unnaturally N-to-N and C-to-C fused proteins can be obtained in 3-4 d.

Psychological impact of the animal-human bond in disaster preparedness and response.

PubMed

Hall, Molly J; Ng, Anthony; Ursano, Robert J; Holloway, Harry; Fullerton, Carol; Casper, Jacob

2004-11-01

The authors present an overview of the impact of the animal-human bond on disaster management and highlight the need to further examine the relationship of animals and humans in disaster response. The human connection to animals influences compliance with individual and community evacuation plans. Search and rescue teams with canine units confront physical and emotional demands that affect both handler and animal. The culling of animal populations on a scale such as occurred during the recent foot-and-mouth epidemic in the United Kingdom affects every member of rural society. Livestock farmers and their families endure enormous emotional losses, and veterinarians and government officials who must implement these programs suffer as well. A familiarity with and understanding of these issues is important for psychiatrists and other mental health professionals who are involved in disaster preparedness and response.

Natural Disasters and Human Behavior: Explanation, Research and Models.

ERIC Educational Resources Information Center

Glenn, Christopher

1979-01-01

A survey of published research determined that individual and group reactions to natural disasters differ greatly and depend partially on the predisaster personality. Four models are examined to explain individual and group reactions to natural disasters. A conglomerate model and a possible structure to future disaster research are offered.…

Disaster Preparedness for University/Community Transit Systems

ERIC Educational Resources Information Center

Robinson, Geary Lynn

2011-01-01

Public transportation, with its open access, creates an opportunity for masses of people to be hurt while using transit services during human-made or natural disasters. This dissertation reviews the body of academic and professional literature and recent disaster events to characterize the current state of preparedness for disasters affecting…

Web 2.0 for Disaster Response and Recovery

ERIC Educational Resources Information Center

Schmidt, Gregory

2010-01-01

Successful disaster response is an exercise in managing human resources under very difficult conditions. Catastrophic disasters can disrupt both the physical communication networks and the social networks critical to efficient response and recovery. While a well-designed disaster plan serves as a framework, it often requires communication and…

Genetic Code Expansion of Mammalian Cells with Unnatural Amino Acids.

PubMed

Brown, Kalyn A; Deiters, Alexander

2015-09-01

The expansion of the genetic code of mammalian cells enables the incorporation of unnatural amino acids into proteins. This is achieved by adding components to the protein biosynthetic machinery, specifically an engineered aminoacyl-tRNA synthetase/tRNA pair. The unnatural amino acids are chemically synthesized and supplemented to the growth medium. Using this methodology, fundamental new chemistries can be added to the functional repertoire of the genetic code of mammalian cells. This protocol outlines the steps necessary to incorporate a photocaged lysine into proteins and showcases its application in the optical triggering of protein translocation to the nucleus. Copyright © 2015 John Wiley & Sons, Inc.

Substance Abuse and Mental Health Services Administration (SAMHSA) Behavioral Health Disaster Response App.

PubMed

Seligman, Jamie; Felder, Stephanie S; Robinson, Maryann E

2015-10-01

The Substance Abuse and Mental Health Services Administration (SAMHSA) in the Department of Health and Human Services offers extensive disaster behavior health resources to assist disaster survivors in preparing for, responding to, and recovering from natural and manmade disasters. One of SAMHSA's most innovative resources is the SAMHSA Behavioral Health Disaster Response App (SAMHSA Disaster App). The SAMHSA Disaster App prepares behavioral health responders for any type of traumatic event by allowing them to access disaster-related materials and other key resources right on their phone, at the touch of a button. The SAMHSA Disaster App is available on iPhone, Android, and BlackBerry devices.

Economic development and declining vulnerability to climate-related disasters in China

NASA Astrophysics Data System (ADS)

Wu, Jidong; Han, Guoyi; Zhou, Hongjian; Li, Ning

2018-03-01

Exposure and vulnerability are the main contributing factors of growing impact from climate-related disasters globally. Understanding the spatiotemporal dynamic patterns of vulnerability is important for designing effective disaster risk mitigation and adaptation measures. At national scale, most cross-country studies have suggested that economic vulnerability to disasters decreases as income increases, especially for developing countries. Research covering sub-national climate-related natural disasters is indispensable to obtaining a comprehensive understanding of the effect of regional economic growth on vulnerability reduction. Taking China as a case, this subnational scale study shows that economic development is correlated with the significant reduction in human fatalities but increase in direct economic losses (DELs) from climate-related disasters since 1949. The long-term trend in climate-related disaster vulnerability, reflected by mortality (1978-2015) and DELs (1990-2015) as a share of the total population and Gross Domestic Product, has seen significant decline among all economic regions in China. While notable differences remain among its West, Central and East economic regions, the temporal vulnerability change has been converging. The study further demonstrated that economic development level is correlated with human and economic vulnerability to climate-related disasters, and this vulnerability decreased with the increase of per-capita income. This study suggested that economic development can have nuanced effects on overall human and economic vulnerability to climate-related disasters. We argue that climate change science needs to acknowledge and examine the different pathways of vulnerability effects related to economic development.

Historical Thinking--and Its Alleged Unnaturalness

ERIC Educational Resources Information Center

Levisohn, Jon A.

2017-01-01

No articulation of "historical thinking" has been as influential as Sam Wineburg's position, according to which historical thinking is, fundamentally, the recognition of the ways in which the past is different than the present. Wineburg argues, further, that achieving that state is "unnatural." This paper critiques both of…

Surviving the Unexpected: A Curriculum Guide for Wilderness Survival and Survival from Natural and Man Made Disasters.

ERIC Educational Resources Information Center

Fear, Daniel E., Ed.; Fear, Eugene H., Ed.

Intended for students in elementary school, secondary school, and adult classes, the curriculum guide presents information about human factors and priorities in three kinds of disasters: wilderness emergencies, natural disasters, and man-made disasters. The guide contains lesson plans in each containing objectives, desired understanding, and…

Five Essential Elements of Crisis Intervention for Communities and Schools When Responding to Technological Disasters

ERIC Educational Resources Information Center

Sulkowski, Michael L.; Lazarus, Philip J.

2013-01-01

Technological disasters result from human error, negligence, or limitations in perceiving and reducing risk. They are a form of manmade disaster that exerts a devastating effect on impacted individuals, communities, and ecosystems. Because of their negative impacts, technological disasters often erode community connectedness, undermine adaptive…

75 FR 16486 - Proposed Comment Request for Review of ACF Disaster Case Management Implementation Guide; Office...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

... Request for Review of ACF Disaster Case Management Implementation Guide; Office of Human Services... in the Federal Register for comments on the ACF Disaster Case Management Implementation Guide, dated December 2009. Disaster case management is the process of organizing and providing a timely, coordinated...

Progress with viral vectored malaria vaccines: A multi-stage approach involving "unnatural immunity".

PubMed

Ewer, Katie J; Sierra-Davidson, Kailan; Salman, Ahmed M; Illingworth, Joseph J; Draper, Simon J; Biswas, Sumi; Hill, Adrian V S

2015-12-22

Viral vectors used in heterologous prime-boost regimens are one of very few vaccination approaches that have yielded significant protection against controlled human malaria infections. Recently, protection induced by chimpanzee adenovirus priming and modified vaccinia Ankara boosting using the ME-TRAP insert has been correlated with the induction of potent CD8(+) T cell responses. This regimen has progressed to field studies where efficacy against infection has now been reported. The same vectors have been used pre-clinically to identify preferred protective antigens for use in vaccines against the pre-erythrocytic, blood-stage and mosquito stages of malaria and this work is reviewed here for the first time. Such antigen screening has led to the prioritization of the PfRH5 blood-stage antigen, which showed efficacy against heterologous strain challenge in non-human primates, and vectors encoding this antigen are in clinical trials. This, along with the high transmission-blocking activity of some sexual-stage antigens, illustrates well the capacity of such vectors to induce high titre protective antibodies in addition to potent T cell responses. All of the protective responses induced by these vectors exceed the levels of the same immune responses induced by natural exposure supporting the view that, for subunit vaccines to achieve even partial efficacy in humans, "unnatural immunity" comprising immune responses of very high magnitude will need to be induced. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Systems for the expression of orthogonal translation components in eubacterial host cells

DOEpatents

Ryu, Youngha; Schultz, Peter G.

2013-01-22

The invention related to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural acids at genetically-programmed positions.

Synthesis of unnatural amino acids via microwave-assisted regio-selective one-pot multi-component reactions of sulfamidates

EPA Science Inventory

Synthesis of triazole-based unnatural amino acids, triazole bisaminoacids and β-amino triazole has been described via stereo and regioselective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW irradiation conditions. The developed method is app...

Systems for the expression of orthogonal translation components in eubacterial host cells

DOEpatents

Ryu, Youngha [San Diego, CA; Schultz, Peter G [La Jolla, CA

2011-06-14

The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.

Systems for the expression of orthogonal translation components eubacterial host cells

DOEpatents

Ryu, Youngha [San Diego, CA; Schultz, Peter G [La Jolla, CA

2012-06-12

The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.

The environmental and medical geochemistry of potentially hazardous materials produced by disasters

USGS Publications Warehouse

Plumlee, Geoffrey S.; Morman, Suzette A.; Meeker, G.P.; Hoefen, Todd M.; Hageman, Philip L.; Wolf, Ruth E.

2014-01-01

Many natural or human-caused disasters release potentially hazardous materials (HM) that may pose threats to the environment and health of exposed humans, wildlife, and livestock. This chapter summarizes the environmentally and toxicologically significant physical, mineralogical, and geochemical characteristics of materials produced by a wide variety of recent disasters, such as volcanic eruptions, hurricanes and extreme storms, spills of mining/mineral-processing wastes or coal extraction by-products, and the 2001 attacks on and collapse of the World Trade Center towers. In describing these characteristics, this chapter also illustrates the important roles that geochemists and other earth scientists can play in environmental disaster response and preparedness. In addition to characterizing in detail the physical, chemical, and microbial makeup of HM generated by the disasters, these roles also include (1) identifying and discriminating potential multiple sources of the materials; (2) monitoring, mapping, and modeling dispersal and evolution of the materials in the environment; (3) understanding how the materials are modified by environmental processes; (4) identifying key characteristics and processes that influence the materials' toxicity to exposed humans and ecosystems; (5) estimating shifts away from predisaster environmental baseline conditions; and (6) using geochemical insights learned from past disasters to help estimate, prepare for, and increase societal resilience to the environmental and related health impacts of future disasters.

Human Trafficking in Nepal: Post-Earthquake Risk and Response.

PubMed

Gyawali, Bishal; Keeling, June; Kallestrup, Per

2017-04-01

As Nepal mourns the 1-year commemoration of the April 2015 earthquake and its aftershocks that killed more than 8500 people and left thousands injured and displaced, other more hidden repercussions of the resultant chaotic environment need attention: the increased risk of human trafficking. Considering that natural disasters provide a milieu for this illicit trade, there is a need for a robust response from stakeholders such as donors, civil society organizations, and government organizations against human trafficking following disasters such as the Nepal earthquake. Responsibility to prevent and fight trafficking should be explicitly included in the mandate of relief and rehabilitation mechanisms set up at the national level to coordinate the disaster relief response, serving to support populations in both rural and urban areas. (Disaster Med Public Health Preparedness. 2017;11:153-154).

Grand Challenges for Disaster Reduction

DTIC Science & Technology

2005-06-01

6—Promote risk-wise behavior. Develop and apply principles of economics and human behavior to enhance communications, trust, and understand- ing...Challenges for Disaster Reduction Promote Risk-Wise Behavior. Develop and apply principles of economics and human behavior to enhance communications

When is a natural disaster a development disaster; when is a natural disaster not a disaster?

NASA Astrophysics Data System (ADS)

Mutter, J. C.; Archibong, B.; Pi, D.

2009-12-01

Extremes of nature like hurricanes, droughts and earthquakes influence human welfare in a variety of ways. While it might seem counterintuitive, evidence from long run macro-economic data suggests that when natural extremes are especially destructive to human societies, and earn the title “natural disaster” they can actually have a beneficial effect on development. The process involved may be akin to the “The gale of creative destruction” first described by the economist Joseph Schumpeter. Applied to disasters the notion is that, in the short term, disasters can stimulate certain industries such as construction with capital flows coming into the disaster region from outside sources such as central government or international aid that can stimulate the economy. Longer term, outdated and inefficient public and private infrastructure destroyed in the disaster can be replaced by up to date, efficient systems that permit the economy to function more effectively, so that post-disaster growth can exceed pre-disaster levels. Disasters are macro-economic shocks, fundamentally similar to the banking shock that lead to the current global recession and, in the same way require external capital stimuli to overcome and that stimulus can result in stronger economies after recovery. These large-scale and long-run trends disguise the fact that disasters have very different development outcomes for different societies. Globally, there is evidence that poorer countries are not systematically stimulated by disaster shocks and may even be driven into poverty traps by certain disasters. Locally, the recovery from Hurricane Katrina in New Orleans has had been very different for different social groups, with both over-recovery and under-recovery occurring simultaneously and in close proximity. We discuss the conditions under which disasters might be a stimulating force and when they might lead to development setbacks.

Chemical Probes for the Functionalization of Polyketide Intermediates**

PubMed Central

Riva, Elena; Wilkening, Ina; Gazzola, Silvia; Li, W M Ariel; Smith, Luke; Leadlay, Peter F; Tosin, Manuela

2014-01-01

A library of functionalized chemical probes capable of reacting with ketosynthase-bound biosynthetic intermediates was prepared and utilized to explore in vivo polyketide diversification. Fermentation of ACP mutants of S. lasaliensis in the presence of the probes generated a range of unnatural polyketide derivatives, including novel putative lasalocid A derivatives characterized by variable aryl ketone moieties and linear polyketide chains (bearing alkyne/azide handles and fluorine) flanking the polyether scaffold. By providing direct information on microorganism tolerance and enzyme processing of unnatural malonyl-ACP analogues, as well as on the amenability of unnatural polyketides to further structural modifications, the chemical probes constitute invaluable tools for the development of novel mutasynthesis and synthetic biology. PMID:25212788

THE ROLE OF FORENSIC DENTIST FOLLOWING MASS DISASTER

PubMed Central

Kolude, B.; Adeyemi, B.F.; Taiwo, J.O.; Sigbeku, O.F.; Eze, U.O.

2010-01-01

This review article focuses on mass disaster situations that may arise from natural or manmade circumstances and the significant role of forensic dental personnel in human identification following such occurrences. The various forensic dental modalities of identification that include matching techniques, postmortem profiling, genetic fingerprinting, dental fossil assessment and dental biometrics with digital subtraction were considered. The varying extent of use of forensic dental techniques and the resulting positive impact on human identification were considered. The importance of preparation by way of special training for forensic dental personnel, mock disaster rehearsal, and use of modern day technology was stressed. The need for international standardization of identification through the use of Interpol Disaster Victim Identification (DVI) for ms was further emphasized. Recommendations for improved human identification in Nigerian situation include reform of the National Emergency Management Association (NEMA), incorporation of dental care in primary health care to facilitate proper ante mortem database of the populace and commencement of identification at site of disaster. PMID:25161478

School Disaster Planning for Children with Disabilities: A Critical Review of the Literature

ERIC Educational Resources Information Center

Boon, Helen J.; Brown, Lawrence H.; Tsey, Komla; Speare, Richard; Pagliano, Paul; Usher, Kim; Clark, Brenton

2011-01-01

Human systems have to adapt to climate change and the natural disasters predicted to increase in frequency as a result. These disasters have both direct and indirect health effects. Certain groups, the poor, the elderly, children and those with disabilities are set to be more seriously impacted by disasters because of their greater inherent…

Stereo- and regio-selective one-pot synthesis of triazole-based unnatural amino acids and β- amino triazoles

EPA Science Inventory

Synthesis of triazole based unnatural amino acids and β-amino triazole has been described via stereo and regioselective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW conditions. The developed method is applicable to a broad substrate scope a...

Retrieving quantifiable social media data from human sensor networks for disaster modeling and crisis mapping

NASA Astrophysics Data System (ADS)

Aulov, Oleg

This dissertation presents a novel approach that utilizes quantifiable social media data as a human aware, near real-time observing system, coupled with geophysical predictive models for improved response to disasters and extreme events. It shows that social media data has the potential to significantly improve disaster management beyond informing the public, and emphasizes the importance of different roles that social media can play in management, monitoring, modeling and mitigation of natural and human-caused extreme disasters. In the proposed approach Social Media users are viewed as "human sensors" that are "deployed" in the field, and their posts are considered to be "sensor observations", thus different social media outlets all together form a Human Sensor Network. We utilized the "human sensor" observations, as boundary value forcings, to show improved geophysical model forecasts of extreme disaster events when combined with other scientific data such as satellite observations and sensor measurements. Several recent extreme disasters are presented as use case scenarios. In the case of the Deepwater Horizon oil spill disaster of 2010 that devastated the Gulf of Mexico, the research demonstrates how social media data from Flickr can be used as a boundary forcing condition of GNOME oil spill plume forecast model, and results in an order of magnitude forecast improvement. In the case of Hurricane Sandy NY/NJ landfall impact of 2012, we demonstrate how the model forecasts, when combined with social media data in a single framework, can be used for near real-time forecast validation, damage assessment and disaster management. Owing to inherent uncertainties in the weather forecasts, the NOAA operational surge model only forecasts the worst-case scenario for flooding from any given hurricane. Geolocated and time-stamped Instagram photos and tweets allow near real-time assessment of the surge levels at different locations, which can validate model forecasts, give timely views of the actual levels of surge, as well as provide an upper bound beyond which the surge did not spread. Additionally, we developed AsonMaps---a crisis-mapping tool that combines dynamic model forecast outputs with social media observations and physical measurements to define the regions of event impacts.

Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture.

PubMed

Runguphan, Weerawat; Maresh, Justin J; O'Connor, Sarah E

2009-08-18

Natural products have long served as both a source and inspiration for pharmaceuticals. Modifying the structure of a natural product often improves the biological activity of the compound. Metabolic engineering strategies to ferment "unnatural" products have been enormously successful in microbial organisms. However, despite the importance of plant derived natural products, metabolic engineering strategies to yield unnatural products from complex, lengthy plant pathways have not been widely explored. Here, we show that RNA mediated suppression of tryptamine biosynthesis in Catharanthus roseus hairy root culture eliminates all production of monoterpene indole alkaloids, a class of natural products derived from two starting substrates, tryptamine and secologanin. To exploit this chemically silent background, we introduced an unnatural tryptamine analog to the production media and demonstrated that the silenced plant culture could produce a variety of novel products derived from this unnatural starting substrate. The novel alkaloids were not contaminated by the presence of the natural alkaloids normally present in C. roseus. Suppression of tryptamine biosynthesis therefore did not appear to adversely affect expression of downstream biosynthetic enzymes. Targeted suppression of substrate biosynthesis therefore appears to be a viable strategy for programming a plant alkaloid pathway to more effectively produce desirable unnatural products. Moreover, although tryptamine is widely found among plants, this silenced line demonstrates that tryptamine does not play an essential role in growth or development in C. roseus root culture. Silencing the biosynthesis of an early starting substrate enhances our ability to harness the rich diversity of plant based natural products.

Awareness of disaster reduction frameworks and risk perception of natural disaster: a questionnaire survey among Philippine and Indonesian health care personnel and public health students.

PubMed

Usuzawa, Motoki; O Telan, Elizabeth; Kawano, Razel; S Dizon, Carmela; Alisjahbana, Bachti; Ashino, Yugo; Egawa, Shinichi; Fukumoto, Manabu; Izumi, Takako; Ono, Yuichi; Hattori, Toshio

2014-05-01

As the impacts of natural disasters have grown more severe, the importance of education for disaster medicine gains greater recognition. We launched a project to establish an international educational program for disaster medicine. In the present study, we surveyed medical personnel and medical/public health students in the Philippines (n = 45) and Indonesia (n = 67) for their awareness of the international frameworks related to disaster medicine: the Human Security (securing individual life and health), the Sphere Project (international humanitarian response), and the Hyogo Framework for Action 2005-2015 (international strategy for disaster reduction). In both countries, more than 50% responders were aware of human security, but only 2 to 12% were aware of the latter two. The survey also contained questions about the preferred subjects in prospective educational program, and risk perception on disaster and disaster-related infections. In the Philippines, significant disasters were geophysical (31.0%), hydrological (33.3%), or meteorological (24.8%), whereas in Indonesia, geophysical (63.0%) and hydrological (25.3%) were significant. Moreover, in the Philippines, leptospirosis (27.1%), dengue (18.6%), diarrhea (15.3%), and cholera (10.2%) were recognized common disaster-related infections. In Indonesia, diarrhea (22.0%) and respiratory infection (20.3%) are major disaster-related infections. Water-related infections were the major ones in both countries, but the profiles of risk perception were different (Pearson's chi-square test, p = 1.469e-05). The responders tended to overestimate the risk of low probability and high consequence such as geophysical disaster. These results are helpful for the development of a postgraduate course for disaster medicine in Asia Pacific countries.

Integrated Research on Disaster Risk - A Review

NASA Astrophysics Data System (ADS)

Beer, T.

2016-12-01

Integrated Research on Disaster Risk, generally known as IRDR, is a decade-long research programme co-sponsored by the International Council for Science (ICSU), the International Social Science Council (ISSC), and the United Nations International Strategy for Disaster Reduction (UNISDR). It is a global, multi-disciplinary approach to dealing with the challenges brought by natural disasters, mitigating their impacts, and improving related policy-making mechanisms. The home page is at: http://www.irdrinternational.org/The research programme was named Integrated Research on Disaster Risk to indicate that it is addressing the challenge of natural and human-induced environmental hazards. In November 2008 and May 2009 respectively, both the ISSC and the UNISDR agreed to join the ICSU in co-sponsoring the IRDR programme. Although the approaches in the sciences vary, the IRDR programme approaches the issues of natural and human-induced hazards and disasters from several perspectives: from the hazards to the disasters, and from the human exposures and vulnerabilities back to the hazards. This coordinated and multi-dimensional approach takes the IRDR programme beyond approaches that have traditionally been undertaken To meet its research objectives the IRDR established four core projects, comprising working groups of experts from diverse disciplines, to formulate new methods in addressing the shortcomings of current disaster risk research. Assessment of Integrated Research on Disaster Risk (AIRDR) Disaster Loss Data (DATA) Forensic Investigations of Disasters (FORIN) Risk Interpretation and Action (RIA) Dr Tom Beer was a member of both the scoping and planning groups and was a member of the committee to undertake a mid-term review of IRDR with the terms of reference being to examine and to report by November 2016. 1. Strategic planning and implementation 2. Governance 3. Secretariat, funding and operations 4. Stakeholders and partnerships 5. Communication, visibility and influence 6. Future development His talk will give an overview of the history and science of IRDR and some of the outcomes of the mid-term review.

Fuzzy Comprehensive Evaluation-Based Disaster Risk Assessment of Desertification in Horqin Sand Land, China

PubMed Central

Wang, Yongfang; Zhang, Jiquan; Guo, Enliang; Sun, Zhongyi

2015-01-01

Desertification is a typical disaster risk event in which human settlements and living environments are destroyed. Desertification Disaster Risk Assessment can control and prevent the occurrence and development of desertification disasters and reduce their adverse influence on human society. This study presents the methodology and procedure for risk assessment and zoning of desertification disasters in Horqin Sand Land. Based on natural disaster risk theory and the desertification disaster formation mechanism, the Desertification Disaster Risk Index (DDRI) combined hazard, exposure, vulnerability and restorability factors and was developed mainly by using multi-source data and the fuzzy comprehensive evaluation method. The results showed that high risk and middle risk areas account for 28% and 23% of the study area, respectively. They are distributed with an “S” type in the study area. Low risk and very low risk areas account for 21% and 10% of the study area, respectively. They are distributed in the west-central and southwestern parts. Very high risk areas account for 18% of the study area and are distributed in the northeastern parts. The results can be used to know the desertification disaster risk level. It has important theoretical and practical significance to prevention and control of desertification in Horqin Sand Land and even in Northern China. PMID:25654772

Fuzzy comprehensive evaluation-based disaster risk assessment of desertification in Horqin Sand Land, China.

PubMed

Wang, Yongfang; Zhang, Jiquan; Guo, Enliang; Sun, Zhongyi

2015-02-03

Desertification is a typical disaster risk event in which human settlements and living environments are destroyed. Desertification Disaster Risk Assessment can control and prevent the occurrence and development of desertification disasters and reduce their adverse influence on human society. This study presents the methodology and procedure for risk assessment and zoning of desertification disasters in Horqin Sand Land. Based on natural disaster risk theory and the desertification disaster formation mechanism, the Desertification Disaster Risk Index (DDRI) combined hazard, exposure, vulnerability and restorability factors and was developed mainly by using multi-source data and the fuzzy comprehensive evaluation method. The results showed that high risk and middle risk areas account for 28% and 23% of the study area, respectively. They are distributed with an "S" type in the study area. Low risk and very low risk areas account for 21% and 10% of the study area, respectively. They are distributed in the west-central and southwestern parts. Very high risk areas account for 18% of the study area and are distributed in the northeastern parts. The results can be used to know the desertification disaster risk level. It has important theoretical and practical significance to prevention and control of desertification in Horqin Sand Land and even in Northern China.

Development of an intermodal training program for disaster relief agencies.

DOT National Transportation Integrated Search

2010-08-01

Natural disasters impact society on a broad level, often leading to both financial damage and the loss of : human life. This project seeks to improve the design and operation of disaster relief chains by providing : agencies with an intermodal transp...

The Scripps Research Institute (La Jolla, CA)

DOEpatents

Schultz, Peter G.; Wang, Lei

2010-01-05

The invention provides proteins attached to solid supports, and methods of preparing such solid support-bound proteins are provided. The proteins are attached to solid supports by means of an unnatural amino acid incorporated into the protein, which unnatural amino acid includes a reactive group that can react with a second reactive group that is attached to a solid support.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W.; Cropp, T. Ashton; Anderson, J. Christopher; Schultz, Peter G.

2013-01-22

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chin, Jason W.; Cropp, T. Ashton; Anderson, J. Christopher

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W [Cambridge, GB; Cropp, T Ashton [Bethesda, MD; Anderson, J Christopher [San Francisco, CA; Schultz, Peter G [La Jolla, CA

2009-10-27

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W; Cropp, T. Ashton; Anderson, J. Christopher; Schultz, Peter G

2015-02-03

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W [Cambridge, GB; Cropp, T Ashton [Bethesda, MD; Anderson, J Christopher [San Francisco, CA; Schultz, Peter G [La Jolla, CA

2009-12-01

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W [Cambridge, GB; Cropp, T Ashton [Bethesda, MD; Anderson, J Christopher [San Francisco, CA; Schultz, Peter G [La Jolla, CA

2012-02-14

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W [Cambridge, GB; Cropp, T Ashton [Bethesda, MD; Anderson, J Christopher [San Francisco, CA; Schultz, Peter G [La Jolla, CA

2009-11-17

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W.; Cropp, T. Ashton; Anderson, J. Christopher; Schultz, Peter G.

2010-09-14

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Expanding the eukaryotic genetic code

DOEpatents

Chin, Jason W [Cambridge, GB; Cropp, T Ashton [Bethesda, MD; Anderson, J Christopher [San Francisco, CA; Schultz, Peter G [La Jolla, CA

2012-05-08

This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

Are human service agencies ready for disasters? Findings from a mixed-methods needs assessment and planning project.

PubMed

Hipper, Thomas J; Orr, Ashley; Chernak, Esther

2015-01-01

A mixed-methods design was used to assess the current capacity of human service agencies to provide services in a major disaster, identify challenges and successful strategies for providing those services, and formulate specific recommendations for government planners and the nonprofit sector to promote the integration of human service agencies into emergency preparedness and response. A web-based survey was completed by 188 unique human service agencies, 31 semistructured interviews were conducted with human service agency and government leaders from southeastern Pennsylvania and the mid-Atlantic region, and a collaborative planning meeting was held to review the findings and develop systems-based recommendations. Survey results indicated that human service agencies serve the most vulnerable communities during disasters and would welcome integration into preparedness and response plans, but they currently face challenges that include a lack of real-time communication and opportunities for collaborative planning with government partners. Interview findings were grouped according to 5 themes that emerged: capacity, coordination, communication, training, and leadership. This study identified recommendations to assist human service agencies, local health departments, and emergency management agencies as they work to ensure that needed human services are available during disasters, despite the resource challenges that most agencies face.

Measuring the way forward in Haiti: grounding disaster relief in the legal framework of human rights.

PubMed

Klasing, Amanda M; Moses, P Scott; Satterthwaite, Margaret L

2011-07-14

This article provides results from an online survey of humanitarian workers and volunteers that was conducted in May and June 2010. The purpose of the survey was to understand how the humanitarian aid system adopts or incorporates human rights into its post-natural disaster work and metrics. Data collected from Haiti suggest that humanitarians have embraced a rights-based approach but that they do not agree about how this is defined or about what standards and indicators can be considered rights-based. This disagreement may reveal that humanitarians are aware of a mismatch between the rights-based approach to post-disaster humanitarian work and the legal framework of human rights. Using participation and accountability as examples, this article identifies and examines this mismatch and suggests that the humanitarian aid system should more fully embrace engagement with the human rights framework. To do so, the article concludes, humanitarian actors and the human rights community should have an open dialogue about the development of metrics that accurately reflect and monitor adherence to the legal framework of human rights. This would allow the humanitarian aid system to ensure its interventions enhance the capacity of the disaster-affected state to fulfill its human rights obligations, and would allow humanitarian and human rights actors alike to measure the impact of such interventions on the realization of human rights in post-natural disaster settings. Copyright © 2011 Klasing, Moses, and Satterthwaite. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

Preparing for veterinary emergencies: disaster management and the Incident Command System.

PubMed

Madigan, J; Dacre, I

2009-08-01

An important question that all veterinary schools should consider is whether veterinary students should be trained to deal with local or regional states of emergency or disasters, such as hurricanes, tornadoes, wildfires, hail and ice storms, wind storms, fires, earthquakes, tsunamis, floods and epidemics. When a large-scale emergency or disaster does strike, the consequences can be dire for the domestic and wild animals of the region and for the humans within the vicinity of seriously and painfully injured animals. The authors argue that emergency preparedness is essential for the veterinary profession to meet its obligations to both animals and humans. The four basic components of disaster management are: mitigation, preparedness, response/emergency relief and recovery.

75 FR 991 - Notice of Meeting; National Commission on Children and Disasters

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-07

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Notice of Meeting; National Commission on Children and Disasters AGENCY: Administration for Children and Families, Department..., January 19, 2010. Agenda: The National Commission on Children and Disasters is hosting a Long-Term...

Supporting Adolescents Exposed to Disasters

ERIC Educational Resources Information Center

Jacobs, Anne K.; Vernberg, Eric; Lee, Stephanie J.

2008-01-01

Adolescents possess numerous strengths and vulnerabilities based on their unique stage of development. When youth experience a disaster, whether natural or human-caused, there are certain considerations to be taken into account when providing them with support. This article describes common adolescent reactions to the impact phase of disasters as…

Welfare effects of natural disasters in developing countries: an examination using multi-dimensional socio-economic indicators

NASA Astrophysics Data System (ADS)

Mutter, J. C.; Deraniyagala, S.; Mara, V.; Marinova, S.

2011-12-01

The study of the socio-economic impacts of natural disasters is still in its infancy. Social scientists have historically regarded natural disasters as exogenous or essentially random perturbations. More recent scholarship treats disaster shocks as endogenous, with pre-existing social, economic and political conditions determining the form and magnitude of disaster impacts. One apparently robust conclusion is that direct economic losses from natural disasters, similar to human losses, are larger (in relative terms) the poorer a country is, yet cross-country regressions show that disasters may accrue economic benefits due to new investments in productive infrastructure, especially if the investment is funded by externally provided capital (Work Bank assistance, private donations, etc) and do not deplete national savings or acquire a debt burden. Some econometric studies also show that the quality of a country's institutions can mitigate the mortality effects of a disaster. The effects on income inequality are such that the poor suffer greater 'asset shocks' and may never recover from a disaster leading to a widening of existing disparities. Natural disasters affect women more adversely than men in terms of life expectancy at birth. On average they kill more women than men or kill women at a younger age than men, and the more so the stronger the disaster. The extent to which women are more likely to die than men or to die at a younger age from the immediate disaster impact or from post-disaster events depends not only on disaster strength itself but also on the socioeconomic status of women in the affected country. Existing research on the economic effects of disasters focus almost exclusively on the impact on economic growth - the growth rate of GDP. GDP however is only a partial indicator of welfare, especially for countries that are in the lower ranks of development status. Very poor communities are typically involved in subsistence level activities or in the informal economy and will not register disaster set backs in GDP accounts. The alterations to their lives can include loss of livelihood, loss of key assets such as livestock, loss of property and loss of savings, reduced life expectancy among survivors, increased poverty rates, increased inequality, greater subsequent maternal and child mortality (due to destruction of health care facilities), reduced education attainment (lack of school buildings), increased gender-based violence and psychological ailments. Our study enhances this literature in two ways. Firstly, it examines the effects of disasters on human development and poverty using cross-country econometric analysis with indicators of welfare that go beyond GDP. We aim to search the impact of disasters on human development and absolute poverty. Secondly we use Peak Ground Acceleration for earthquakes, a modified Palmer Drought Severity and Hurricane Energy rather than disaster event occurrence to account for the severity of the disaster.

Utilizing Unnatural Amino Acids to Illustrate Protein Structure-Function Relationships: An Experiment Designed for an Undergraduate Biochemistry Laboratory

ERIC Educational Resources Information Center

Maza, Johnathan C.; Villa, Jordan K.; Landino, Lisa M.; Young, Douglas D

2016-01-01

The site-specific introduction of unnatural amino acids (UAAs) has been demonstrated to be a useful tool in protein engineering. Moreover, the incorporation of a UAA into a protein has become feasible with the increased commercial availability of UAAs and robust expression plasmids. In addition to the ease of incorporation, the concepts utilized…

"Unnatural Deeds Do Breed Unnatural Troubles": A Study of Lady Macbeth's Cruelty

ERIC Educational Resources Information Center

Rahman, Muhammad Safiur; Tajuddin, Mohammad

2015-01-01

The study of evil is one of the recurrent themes in the plays of Shakespeare. In "Macbeth," the playwright presents different dimensions of evil. The aim of this paper is to locate and examine the origin of evil in Lady Macbeth--whether evil is in her nature or not. Macbeth addresses her as "dearest partner of greatness",…

Enlightening Butterfly Conservation Efforts: The Importance of Natural Lighting for Butterfly Behavioral Ecology and Conservation

PubMed Central

2018-01-01

Light is arguably the most important abiotic factor for living organisms. Organisms evolved under specific lighting conditions and their behavior, physiology, and ecology are inexorably linked to light. Understanding light effects on biology could not be more important as present anthropogenic effects are greatly changing the light environments in which animals exist. The two biggest anthropogenic contributors changing light environments are: (1) anthropogenic lighting at night (i.e., light pollution); and (2) deforestation and the built environment. I highlight light importance for butterfly behavior, physiology, and ecology and stress the importance of including light as a conservation factor for conserving butterfly biodiversity. This review focuses on four parts: (1) Introducing the nature and extent of light. (2) Visual and non-visual light reception in butterflies. (3) Implications of unnatural lighting for butterflies across several different behavioral and ecological contexts. (4). Future directions for quantifying the threat of unnatural lighting on butterflies and simple approaches to mitigate unnatural light impacts on butterflies. I urge future research to include light as a factor and end with the hopeful thought that controlling many unnatural light conditions is simply done by flipping a switch. PMID:29439549

Brain synchronization during perception of facial emotional expressions with natural and unnatural dynamics

PubMed Central

Volhard, Jakob; Müller, Viktor; Kaulard, Kathrin; Brick, Timothy R.; Wallraven, Christian; Lindenberger, Ulman

2017-01-01

Research on the perception of facial emotional expressions (FEEs) often uses static images that do not capture the dynamic character of social coordination in natural settings. Recent behavioral and neuroimaging studies suggest that dynamic FEEs (videos or morphs) enhance emotion perception. To identify mechanisms associated with the perception of FEEs with natural dynamics, the present EEG (Electroencephalography)study compared (i) ecologically valid stimuli of angry and happy FEEs with natural dynamics to (ii) FEEs with unnatural dynamics, and to (iii) static FEEs. FEEs with unnatural dynamics showed faces moving in a biologically possible but unpredictable and atypical manner, generally resulting in ambivalent emotional content. Participants were asked to explicitly recognize FEEs. Using whole power (WP) and phase synchrony (Phase Locking Index, PLI), we found that brain responses discriminated between natural and unnatural FEEs (both static and dynamic). Differences were primarily observed in the timing and brain topographies of delta and theta PLI and WP, and in alpha and beta WP. Our results support the view that biologically plausible, albeit atypical, FEEs are processed by the brain by different mechanisms than natural FEEs. We conclude that natural movement dynamics are essential for the perception of FEEs and the associated brain processes. PMID:28723957

Brain synchronization during perception of facial emotional expressions with natural and unnatural dynamics.

PubMed

Perdikis, Dionysios; Volhard, Jakob; Müller, Viktor; Kaulard, Kathrin; Brick, Timothy R; Wallraven, Christian; Lindenberger, Ulman

2017-01-01

Research on the perception of facial emotional expressions (FEEs) often uses static images that do not capture the dynamic character of social coordination in natural settings. Recent behavioral and neuroimaging studies suggest that dynamic FEEs (videos or morphs) enhance emotion perception. To identify mechanisms associated with the perception of FEEs with natural dynamics, the present EEG (Electroencephalography)study compared (i) ecologically valid stimuli of angry and happy FEEs with natural dynamics to (ii) FEEs with unnatural dynamics, and to (iii) static FEEs. FEEs with unnatural dynamics showed faces moving in a biologically possible but unpredictable and atypical manner, generally resulting in ambivalent emotional content. Participants were asked to explicitly recognize FEEs. Using whole power (WP) and phase synchrony (Phase Locking Index, PLI), we found that brain responses discriminated between natural and unnatural FEEs (both static and dynamic). Differences were primarily observed in the timing and brain topographies of delta and theta PLI and WP, and in alpha and beta WP. Our results support the view that biologically plausible, albeit atypical, FEEs are processed by the brain by different mechanisms than natural FEEs. We conclude that natural movement dynamics are essential for the perception of FEEs and the associated brain processes.

Teaching Disaster Preparedness in Geographic Education

ERIC Educational Resources Information Center

Fuhrmann, Sven; Stone, Lee D.; Casey, Melinda C.; Curtis, Mary D.; Doyle, Amber L.; Earle, Brian D.; Jones, Douglas D.; Rodriguez, Philip; Schermerhorn, Steven M.

2008-01-01

Extreme natural and human-made disasters can affect the lives of thousands of citizens. The only way we can prepare ourselves for such situations is to learn and establish basic survival strategies within our families and communities. This article explores how K-12 teachers could help educating children about disaster preparedness by utilizing…

Are natural and unnatural appetites equally controllable? A response to Jensen's "Is continence enough?".

PubMed

Smith, Janet E

2004-01-01

This response challenges Jensen's analysis in no substantial way. Rather, it explains more fully some of the moral character categories that Aristotle provides. It argues that Aristotle understood there to be two forms of continence: the continence that enables us to control natural appetites and"some form"of continence directed towards unnatural appetites, generally engendered by some pathology or abuse.

Space and time scales in human-landscape systems.

PubMed

Kondolf, G Mathias; Podolak, Kristen

2014-01-01

Exploring spatial and temporal scales provides a way to understand human alteration of landscape processes and human responses to these processes. We address three topics relevant to human-landscape systems: (1) scales of human impacts on geomorphic processes, (2) spatial and temporal scales in river restoration, and (3) time scales of natural disasters and behavioral and institutional responses. Studies showing dramatic recent change in sediment yields from uplands to the ocean via rivers illustrate the increasingly vast spatial extent and quick rate of human landscape change in the last two millennia, but especially in the second half of the twentieth century. Recent river restoration efforts are typically small in spatial and temporal scale compared to the historical human changes to ecosystem processes, but the cumulative effectiveness of multiple small restoration projects in achieving large ecosystem goals has yet to be demonstrated. The mismatch between infrequent natural disasters and individual risk perception, media coverage, and institutional response to natural disasters results in un-preparedness and unsustainable land use and building practices.

Natural Disasters and Cultural Responses. Studies in Third World Societies. Publication Number Thirty-six.

ERIC Educational Resources Information Center

Oliver-Smith, Anthony, Ed.

This collection of articles focuses on natural disasters from earthquakes to famines in developing nations and on the human response from immediate reactions to long term social, political, and economic adaptations that result in social change and development. The introduction, "Disaster Context and Causation: An Overview of Changing Perspectives…

Disaster Preparedness Manual.

ERIC Educational Resources Information Center

Michael, Douglas O.

Prepared for use by the staff of a community college library, this manual describes the natural, building, and human hazards which can result in disaster in a library and outlines a set of disaster prevention measures and salvage procedures. A list of salvage priorities, floor plans for all three levels of Bourke Memorial Library, and staff duties…

Lifelong Learning from Natural Disasters: Transformative Group-Based Learning at Philippine Universities

ERIC Educational Resources Information Center

Dahl, Kari Kragh Blume; Millora, Christopher Malagad

2016-01-01

This study explores reflective experience during transformative, group-based learning among university leaders following a natural disaster such as a typhoon in two Philippine universities. Natural disasters are recurrent phenomena in many parts of the world, but the literature largely ignores their impact on lifelong human learning, for instance…

International Wildfire Emergencies: Management in the 21st Century

Treesearch

Julia V. Taft; Robert W. Mutch

1987-01-01

The U.S. Government, through the U.S. Agency for International Development's Office of U.S. Foreign Disaster Assistance (OFDA), responds to a wide variety of disasters throughout the world every year. These disasters range from "slow-moving" events like prolonged drought or plagues of grasshoppers and locusts to "fast-moving" threats to human...

Companion Animals in Natural Disasters: A Scoping Review of Scholarly Sources.

PubMed

Travers, Cheryl; Degeling, Chris; Rock, Melanie

2017-01-01

During a disaster, people may make evacuation decisions based on their companion animal's welfare, therefore exposing themselves, their companion animals, and emergency responders to increased risk for injury or death. The loss and suffering of companion animals in disasters causes deep distress, diminishing people's capacity to rebuild their lives. This scoping review presents scholarly research studies and reviews relating to people and their companion animals in the context of disasters, with an aim of informing researchers, policymakers, and practitioners and providing direction for future research. Using the Arksey and O'Malley framework, articles in scholarly journals from 2004 to 2014 are discussed. Analysis included 38 articles: 20 research studies, 12 reviews, and 6 editorials. Findings revealed 2 central themes: companion animals as a risk factor to human health and safety and companion animals being "at risk" themselves. An emerging theme was "responsibility": Who is responsible for companion animals in disasters and how? Understanding the implications of human-nonhuman animal relationships for disaster response and having a broader public consensus on what is owed to animals at times of emergency are important to community preparedness and resilience.

Army Support during the Hurricane Katrina Disaster

DTIC Science & Technology

2009-01-01

Human Capital Reform Act of 2004. 3. John D. Banusiewicz, “Bush Calls for Broader Military Disaster Response Role,” American Forces Press Service...Management (DHS/FEMA) ESF #6, Mass Care, Housing, and Human Services (DHS/FEMA) ESF #7, Resource Support (Government Services Administration) ESF #8...Public Health and Medical Services (Department of Health and Human Services) ESF #9, Urban Search and Rescue (DHS/FEMA) ESF #10, Oil and Hazardous

Post-traumatic stress disorder associated with natural and human-made disasters in the World Mental Health Surveys

PubMed Central

Bromet, E. J.; Atwoli, L.; Kawakami, N.; Navarro-Mateu, F.; Piotrowski, P.; King, A. J.; Aguilar-Gaxiola, S.; Alonso, J.; Bunting, B.; Demyttenaere, K.; Florescu, S.; de Girolamo, G.; Gluzman, S.; Haro, J. M.; de Jonge, P.; Karam, E. G.; Lee, S.; Kovess-Masfety, V.; Medina-Mora, M. E.; Mneimneh, Z.; Pennell, B.-E.; Posada-Villa, J.; Salmerón, D.; Takeshima, T.; Kessler, R. C.

2017-01-01

Background Research on post-traumatic stress disorder (PTSD) following natural and human-made disasters has been undertaken for more than three decades. Although PTSD prevalence estimates vary widely, most are in the 20–40% range in disaster-focused studies but considerably lower (3–5%) in the few general population epidemiological surveys that evaluated disaster-related PTSD as part of a broader clinical assessment. The World Mental Health (WMH) Surveys provide an opportunity to examine disaster-related PTSD in representative general population surveys across a much wider range of sites than in previous studies. Method Although disaster-related PTSD was evaluated in 18 WMH surveys, only six in high-income countries had enough respondents for a risk factor analysis. Predictors considered were socio-demographics, disaster characteristics, and pre-disaster vulnerability factors (childhood family adversities, prior traumatic experiences, and prior mental disorders). Results Disaster-related PTSD prevalence was 0.0–3.8% among adult (ages 18+) WMH respondents and was significantly related to high education, serious injury or death of someone close, forced displacement from home, and pre-existing vulnerabilities (prior childhood family adversities, other traumas, and mental disorders). Of PTSD cases 44.5% were among the 5% of respondents classified by the model as having highest PTSD risk. Conclusion Disaster-related PTSD is uncommon in high-income WMH countries. Risk factors are consistent with prior research: severity of exposure, history of prior stress exposure, and pre-existing mental disorders. The high concentration of PTSD among respondents with high predicted risk in our model supports the focus of screening assessments that identify disaster survivors most in need of preventive interventions. PMID:27573281

School Health: an essential strategy in promoting community resilience and preparedness for natural disasters.

PubMed

Takahashi, Kenzo; Kodama, Mitsuya; Gregorio, Ernesto R; Tomokawa, Sachi; Asakura, Takashi; Waikagul, Jitra; Kobayashi, Jun

2015-01-01

The Third UN World Conference on Disaster Risk Reduction recommended the implementation of the Sendai Framework for Disaster Risk Reduction 2015-2030, which aims to achieve substantial risk reduction and to avoid various disaster-associated losses, including human lives and livelihoods, based on the lessons from the implementation of the Hyogo framework. However, the recommendations did not lay enough stress on the school and the Safe School Concept, which are the core components of a disaster response. To raise the issue of the importance of schools in disaster response. For human capacity building to avoid the damage caused by natural disasters, we should focus on the function of schools in the community and on school health framework. Schools perform a range of functions, which include being a landmark place for evacuation, acting as a participatory education hub among communities (students are usually from the surrounding communities), and being a sustainable source of current disaster-related information. In 2007, the Bangkok Action Agenda (BAA) on school education and disaster risk reduction (DRR) recommended the integration of DRR into education policy development, the enhancement of participatory mechanisms to improve DRR education, and the extension of DRR education from schools to communities. Based on our discussion and the recommendations of the BAA, we suggest that our existing challenges are to construct a repository of disaster-related lessons, develop training materials based on current information drawn from previous disasters, and disseminate the training to schools and communities. Schools linked with school health can provide good opportunities for DRR with a focus on development of school health policy and a community-oriented participatory approach.

Post-traumatic stress disorder associated with natural and human-made disasters in the World Mental Health Surveys.

PubMed

Bromet, E J; Atwoli, L; Kawakami, N; Navarro-Mateu, F; Piotrowski, P; King, A J; Aguilar-Gaxiola, S; Alonso, J; Bunting, B; Demyttenaere, K; Florescu, S; de Girolamo, G; Gluzman, S; Haro, J M; de Jonge, P; Karam, E G; Lee, S; Kovess-Masfety, V; Medina-Mora, M E; Mneimneh, Z; Pennell, B-E; Posada-Villa, J; Salmerón, D; Takeshima, T; Kessler, R C

2017-01-01

Research on post-traumatic stress disorder (PTSD) following natural and human-made disasters has been undertaken for more than three decades. Although PTSD prevalence estimates vary widely, most are in the 20-40% range in disaster-focused studies but considerably lower (3-5%) in the few general population epidemiological surveys that evaluated disaster-related PTSD as part of a broader clinical assessment. The World Mental Health (WMH) Surveys provide an opportunity to examine disaster-related PTSD in representative general population surveys across a much wider range of sites than in previous studies. Although disaster-related PTSD was evaluated in 18 WMH surveys, only six in high-income countries had enough respondents for a risk factor analysis. Predictors considered were socio-demographics, disaster characteristics, and pre-disaster vulnerability factors (childhood family adversities, prior traumatic experiences, and prior mental disorders). Disaster-related PTSD prevalence was 0.0-3.8% among adult (ages 18+) WMH respondents and was significantly related to high education, serious injury or death of someone close, forced displacement from home, and pre-existing vulnerabilities (prior childhood family adversities, other traumas, and mental disorders). Of PTSD cases 44.5% were among the 5% of respondents classified by the model as having highest PTSD risk. Disaster-related PTSD is uncommon in high-income WMH countries. Risk factors are consistent with prior research: severity of exposure, history of prior stress exposure, and pre-existing mental disorders. The high concentration of PTSD among respondents with high predicted risk in our model supports the focus of screening assessments that identify disaster survivors most in need of preventive interventions.

Mortality among discharged psychiatric patients in Florence, Italy.

PubMed

Meloni, Debora; Miccinesi, Guido; Bencini, Andrea; Conte, Michele; Crocetti, Emanuele; Zappa, Marco; Ferrara, Maurizio

2006-10-01

Psychiatric disorders involve an increased risk of mortality. In Italy psychiatric services are community based, and hospitalization is mostly reserved for patients with acute illness. This study examined mortality risk in a cohort of psychiatric inpatients for 16 years after hospital discharge to assess the association of excess mortality from natural or unnatural causes with clinical and sociodemographic variables and time from first admission. At the end of 2002 mortality and cause of death were determined for all patients (N=845) who were admitted during 1987 to the eight psychiatric units active in Florence. The mortality risk of psychiatric patients was compared with that of the general population of the region of Tuscany by calculating standardized mortality ratios (SMRs). Poisson multivariate analyses of the observed-to-expected ratio for natural and unnatural deaths were conducted. The SMR for the sample of psychiatric patients was threefold higher than that for the general population (SMR=3.0; 95 percent confidence interval [CI]=2.7-3.4). Individuals younger than 45 years were at higher risk (SMR=11.0; 95 percent CI 8.0-14.9). The SMR for deaths from natural causes was 2.6 (95 percent CI=2.3-2.9), and for deaths from unnatural causes it was 13.0 (95 percent CI=10.1-13.6). For deaths from unnatural causes, the mortality excess was primarily limited to the first years after the first admission. For deaths from natural causes, excess mortality was more stable during the follow-up period. Prevention of deaths from unnatural causes among psychiatric patients may require promotion of earlier follow-up after discharge. Improving prevention and treatment of somatic diseases of psychiatric patients is important to reduce excess mortality from natural causes.

Stealth Disasters and Geoethics

NASA Astrophysics Data System (ADS)

Kieffer, Susan W.

2013-04-01

Natural processes of the earth unleash energy in ways that are sometimes harmful or, at best, inconvenient, for humans: earthquakes, volcanic eruptions, hurricanes, landslides, floods. Ignoring the biological component of the geosphere, we have historically called such events "natural disasters." They are typically characterized by a sudden onset and relatively immediate consequences. There are many historical examples and our human societies have evolved various ways of coping with them logistically, economically, and psychologically. Preparation, co-existence, recovery, and remediation are possible, at least to some extent, even in the largest of events. Geoethical questions exist in each stage, but the limited local extent of these disasters allows the possibility of discussion and resolution. There are other disasters that involve the natural systems that support us. Rather than being driven primarily by natural non-biological processes, these are driven by human behavior. Examples are climate change, desertification, acidification of the oceans, and compaction and erosion of fertile soils. They typically have more gradual onsets than natural disasters and, because of this, I refer to these as "stealth disasters." Although they are unfolding unnoticed or ignored by many, they are having near-term consequences. At a global scale they are new to human experience. Our efforts at preparation, co-existence, recovery, and remediation lag far behind those that we have in place for natural disasters. Furthermore, these four stages in stealth disaster situations involve many ethical questions that typically must be solved in the context of much larger cultural and social differences than encountered in natural disaster settings. Four core ethical principles may provide guidelines—autonomy, non-maleficence, beneficence, and justice (e.g., Jamais Cascio). Geoscientists can contribute to the solutions in many ways. We can work to ensure that as people take responsibility for their own lives (autonomy), they have relevant information in useable form. To minimize harm to others and the environment (non-maleficence), we can design and implement sustainable ways to extract resources and dispose of waste. To advance the welfare of humankind (beneficence), we can work with engineers on innovative uses for commodities that are easily-obtained, and on replacements for rare ones. And, we can strive toward social justice by recognizing that social, ethical, legal and political issues regarding resource use may be far more difficult than the geotechnical ones, and work within the (sometimes frustrating) framework for resolution of those issues. Referring back to the four stages of co-existence with natural disasters (preparation, co-existence, recovery, and remediation), the global scope of stealth disasters raises far more geoethical issues than we have encountered with natural disasters. Just as we have learned (e.g., Hurricanes Katrina and Sandy in the U.S.) that inter-agency response is crucial to successful management of natural disasters, we can expect that global cooperation in management and governance will be essential to the management of stealth disasters. It is imperative that research and education of current and future geoscientists in universities recognize the newly developing role of the geosciences in stealth disasters and that we train our students for a future within this context.

Regioselective and stereoselective route to N2-β-tetrazolyl unnatural nucleosides via SN2 reaction at the anomeric center of Hoffer's chlorosugar.

PubMed

Bag, Subhendu Sekhar; Talukdar, Sangita; Anjali, S J

2016-04-15

We are reporting a regioselective and stereoselective route to N2-β-tetrazolyl aromatic donor/acceptor unnatural nucleosides as new class of possible DNA base analogs. The SN2 substitution reaction at the anomeric center of Hoffer's chlorosugar with various 5-substituted aromatic tetrazoles in THF in presence of K2CO3 proceeds with regioselectivity at N2-tetrazoles and stereoselectivity at α-chlorosugar with very good yield. The stereoelectronic and steric effects play a crucial role for the observed outcome which is also supported from a theoretical (DFT) study. The methodology is simple, eco-compatible and the tetrazolyl unnatural nucleosides might find applications in decorating DNA for various biotechnological and DNA based material science applications. Copyright © 2016 Elsevier Ltd. All rights reserved.

Living with disasters: social capital for disaster governance.

PubMed

Melo Zurita, Maria de Lourdes; Cook, Brian; Thomsen, Dana C; Munro, Paul G; Smith, Timothy F; Gallina, John

2017-10-24

This paper explores how social networks and bonds within and across organisations shape disaster operations and strategies. Local government disaster training exercises serve as a window through which to view these relations, and 'social capital' is used as an analytic for making sense of the human relations at the core of disaster management operations. These elements help to expose and substantiate the often intangible relations that compose the culture that exists, and that is shaped by preparations for disasters. The study reveals how this social capital has been generated through personal interactions, which are shared among disaster managers across different organisations and across 'levels' within those organisations. Recognition of these 'group resources' has significant implications for disaster management in which conducive social relations have become paramount. The paper concludes that socio-cultural relations, as well as a people-centred approach to preparations, appear to be effective means of readying for, and ultimately responding to, disasters. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

Exploring the relationship between cyberbullying and unnatural child death: an ecological study of twenty-four European countries

PubMed Central

2014-01-01

Background Internet risk has been recognised as a child safety problem, but evidence is insufficient to conclude that a child’s online risk exposure can lead to physical harm. This study aims to explore the ecological relationship between Internet risk exposure and unnatural child death. Methods Multiple secondary data sources were used: online exposure to content about self-harm, cyberbullying, and Internet addiction data (EU Kids Online survey, 2010); and mortality data (European Detailed Mortality Database, 2010 or the latest year if not available) of 24 European countries. Correlations were found using quasi-Poisson regression. Countries’ prevalence rates of psychiatric problems (European Social Survey Round 3 and 6, 2006 and 2012) were used to test for possible spuriousness. Results This study finds that countries with higher rates of cyberbullying were more likely to have a higher incidence of unnatural child death. A 1 percent rise in the prevalence of cyberbullying translated into a 28% increase in risk of unnatural child death (95% CI: 2%-57%). No evidence was found to substantiate confounding effect of the national prevalence of depressive symptoms or traditional bullying. Conclusions Explanations are given for the findings. We conclude that intervention programs designed to serve as precautionary measures for risk minimisation should be considered. PMID:25079144

Steric and thermodynamic limits of design for the incorporation of large unnatural amino acids in aminoacyl-tRNA synthetase enzymes.

PubMed

Armen, Roger S; Schiller, Stefan M; Brooks, Charles L

2010-06-01

Orthogonal aminoacyl-tRNA synthetase/tRNA pairs from archaea have been evolved to facilitate site specific in vivo incorporation of unnatural amino acids into proteins in Escherichia coli. Using this approach, unnatural amino acids have been successfully incorporated with high translational efficiency and fidelity. In this study, CHARMM-based molecular docking and free energy calculations were used to evaluate rational design of specific protein-ligand interactions for aminoacyl-tRNA synthetases. A series of novel unnatural amino acid ligands were docked into the p-benzoyl-L-phenylalanine tRNA synthetase, which revealed that the binding pocket of the enzyme does not provide sufficient space for significantly larger ligands. Specific binding site residues were mutated to alanine to create additional space to accommodate larger target ligands, and then mutations were introduced to improve binding free energy. This approach was used to redesign binding sites for several different target ligands, which were then tested against the standard 20 amino acids to verify target specificity. Only the synthetase designed to bind Man-alpha-O-Tyr was predicted to be sufficiently selective for the target ligand and also thermodynamically stable. Our study suggests that extensive redesign of the tRNA synthatase binding pocket for large bulky ligands may be quite thermodynamically unfavorable.

Improving a natural enzyme activity through incorporation of unnatural amino acids.

PubMed

Ugwumba, Isaac N; Ozawa, Kiyoshi; Xu, Zhi-Qiang; Ely, Fernanda; Foo, Jee-Loon; Herlt, Anthony J; Coppin, Chris; Brown, Sue; Taylor, Matthew C; Ollis, David L; Mander, Lewis N; Schenk, Gerhard; Dixon, Nicholas E; Otting, Gottfried; Oakeshott, John G; Jackson, Colin J

2011-01-19

The bacterial phosphotriesterases catalyze hydrolysis of the pesticide paraoxon with very fast turnover rates and are thought to be near to their evolutionary limit for this activity. To test whether the naturally evolved turnover rate could be improved through the incorporation of unnatural amino acids and to probe the role of peripheral active site residues in nonchemical steps of the catalytic cycle (substrate binding and product release), we replaced the naturally occurring tyrosine amino acid at position 309 with unnatural L-(7-hydroxycoumarin-4-yl)ethylglycine (Hco) and L-(7-methylcoumarin-4-yl)ethylglycine amino acids, as well as leucine, phenylalanine, and tryptophan. Kinetic analysis suggests that the 7-hydroxyl group of Hco, particularly in its deprotonated state, contributes to an increase in the rate-limiting product release step of substrate turnover as a result of its electrostatic repulsion of the negatively charged 4-nitrophenolate product of paraoxon hydrolysis. The 8-11-fold improvement of this already highly efficient catalyst through a single rationally designed mutation using an unnatural amino acid stands in contrast to the difficulty in improving this native activity through screening hundreds of thousands of mutants with natural amino acids. These results demonstrate that designer amino acids provide easy access to new and valuable sequence and functional space for the engineering and evolution of existing enzyme functions.

An amino acid depleted cell-free protein synthesis system for the incorporation of non-canonical amino acid analogs into proteins.

PubMed

Singh-Blom, Amrita; Hughes, Randall A; Ellington, Andrew D

2014-05-20

Residue-specific incorporation of non-canonical amino acids into proteins is usually performed in vivo using amino acid auxotrophic strains and replacing the natural amino acid with an unnatural amino acid analog. Herein, we present an efficient amino acid depleted cell-free protein synthesis system that can be used to study residue-specific replacement of a natural amino acid by an unnatural amino acid analog. This system combines a simple methodology and high protein expression titers with a high-efficiency analog substitution into a target protein. To demonstrate the productivity and efficacy of a cell-free synthesis system for residue-specific incorporation of unnatural amino acids in vitro, we use this system to show that 5-fluorotryptophan and 6-fluorotryptophan substituted streptavidin retain the ability to bind biotin despite protein-wide replacement of a natural amino acid for the amino acid analog. We envisage this amino acid depleted cell-free synthesis system being an economical and convenient format for the high-throughput screening of a myriad of amino acid analogs with a variety of protein targets for the study and functional characterization of proteins substituted with unnatural amino acids when compared to the currently employed in vivo methodologies. Copyright © 2014 Elsevier B.V. All rights reserved.

Professional responsibilities versus familial responsibilities: an examination of role conflict among first responders during the Hurricane Katrina disaster.

PubMed

Adams, Terri; Turner, Mila

2014-01-01

In the event of a human-caused or natural disaster, the police are essential front-line first responders. The ability of police departments to provide adequate services is contingent upon critical response personnel working and functioning in an efficient manner. Currently, it is assumed that first responders will continue to work in the event of a disaster, even if they are personally impacted by the disaster to which they are expected to respond. This study examines role conflict among police officers who served as first responders during the Hurricane Katrina disaster.

Computational Psychometrics for Modeling System Dynamics during Stressful Disasters.

PubMed

Cipresso, Pietro; Bessi, Alessandro; Colombo, Desirée; Pedroli, Elisa; Riva, Giuseppe

2017-01-01

Disasters can be very stressful events. However, computational models of stress require data that might be very difficult to collect during disasters. Moreover, personal experiences are not repeatable, so it is not possible to collect bottom-up information when building a coherent model. To overcome these problems, we propose the use of computational models and virtual reality integration to recreate disaster situations, while examining possible dynamics in order to understand human behavior and relative consequences. By providing realistic parameters associated with disaster situations, computational scientists can work more closely with emergency responders to improve the quality of interventions in the future.

Subject Reaction to Human-Caused and Naturally-Occurring Radioactive Threat.

ERIC Educational Resources Information Center

Belford, Susan; Gibbs, Margaret

While research has shown that people are adversely psychologically affected by knowledge that their communities have been toxically contaminated, it has been suggested that those who see a disaster as naturally occurring tend to be less adversely affected than those who see a disaster as caused by human acts. To examine this issue, questionnaires…

A Conceptual Model to Assess Stress-Associated Health Effects of Multiple Ecosystem Services Degraded by Disaster Events in the Gulf of Mexico and Elsewhere

EPA Science Inventory

Few conceptual frameworks attempt to connect disaster-associated environmental injuries to impacts on ecosystem services (the benefits humans derive from nature) and thence to both psychological and physiological human health effects. To our knowledge, this study is one of the fi...

Natural Disaster: Long-Range Impact on Human Response to Future Disaster Threats.

ERIC Educational Resources Information Center

Hanson, Susan; And Others

1979-01-01

The study examines the effect of a prior tornado disaster occurring in a community and that community's current response to a tornado threat. The study concludes that it is not past experience with tornadoes that relates to response to warnings, but rather awareness. Experience is but one source of information contributing to their awareness. (RE)

Assessing disaster preparedness and mental health of community members in Aceh, Indonesia: a community-based, descriptive household survey of a national program.

PubMed

Ismail, Nizam; Suwannapong, Nawarat; Howteerakul, Nopporn; Tipayamongkholgul, Mathuros; Apinuntavech, Suporn

2016-01-01

Disaster preparedness of the community is an essential disaster-mitigation strategy to protect human life and to prevent injuries and property damage. This study aimed to assess the knowledge of disaster, and the disaster preparedness of community members in Aceh, Indonesia. A community-based descriptive household survey was conducted in 40 villages of three tsunami-affected districts in Aceh State, Indonesia. In total, 827 randomly selected community members were interviewed with structured questionnaires during the period September-October 2014. About 57.6% of community members had good knowledge of disaster, while 26.0% had good community disaster preparedness. Neither knowledge of disaster nor disaster preparedness of community members achieved the target of the Community Mental Health Nurse Program outcome indicators (<70.0%). The proportions of people with good knowledge of disaster and disaster preparedness were quite low. The government of Aceh State should revitalize the program to improve the effectiveness of community mental health nurses in transferring the knowledge of disasters and disaster preparedness to the community's members, then expand it to other provinces of Indonesia, using standard approaches and the lessons learned from Aceh.

A qualitative examination of the health workforce needs during climate change disaster response in Pacific Island Countries

PubMed Central

2014-01-01

Background There is a growing body of evidence that the impacts of climate change are affecting population health negatively. The Pacific region is particularly vulnerable to climate change; a strong health-care system is required to respond during times of disaster. This paper examines the capacity of the health sector in Pacific Island Countries to adapt to changing disaster response needs, in terms of: (i) health workforce governance, management, policy and involvement; (ii) health-care capacity and skills; and (iii) human resources for health training and workforce development. Methods Key stakeholder interviews informed the assessment of the capacity of the health sector and disaster response organizations in Pacific Island Countries to adapt to disaster response needs under a changing climate. The research specifically drew upon and examined the adaptive capacity of individual organizations and the broader system of disaster response in four case study countries (Fiji, Cook Islands, Vanuatu and Samoa). Results ‘Capacity’ including health-care capacity was one of the objective determinants identified as most significant in influencing the adaptive capacity of disaster response systems in the Pacific. The research identified several elements that could support the adaptive capacity of the health sector such as: inclusive involvement in disaster coordination; policies in place for health workforce coordination; belief in their abilities; and strong donor support. Factors constraining adaptive capacity included: weak coordination of international health personnel; lack of policies to address health worker welfare; limited human resources and material resources; shortages of personnel to deal with psychosocial needs; inadequate skills in field triage and counselling; and limited capacity for training. Conclusion Findings from this study can be used to inform the development of human resources for health policies and strategic plans, and to support the development of a coordinated and collaborative approach to disaster response training across the Pacific and other developing contexts. This study also provides an overview of health-care capacity and some of the challenges and strengths that can inform future development work by humanitarian organizations, regional and international donors involved in climate change adaptation, and disaster risk reduction in the Pacific region. PMID:24521057

Why are natural disasters not 'natural' for victims?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumagai, Yoshitaka; Edwards, John; Carroll, Matthew S.

Some type of formal or informal social assessment is often carried out in the wake of natural disasters. One often-observed phenomenon in such situations is that disaster victims and their sympathizers tend to focus on those elements of disasters that might have been avoided or mitigated by human intervention and thus assign 'undue' levels of responsibility to human agents. Often the responsibility or blame is directed at the very government agencies charged with helping people cope with and recover from the event. This phenomenon presents particular challenges for those trying to understand the social impacts of such events because ofmore » the reflexive nature of such analysis. Often the social analyst or even the government agency manager must sort through such perceptions and behavior and (at least implicitly) make judgments about which assignments of responsibility may have some validity and which are largely the result of the psychology of the disaster itself. This article presents a conceptual framework derived largely from social psychology to help develop a better understand such perceptions and behavior. While no 'magic bullet' formula for evaluating the validity of disaster victims' claims is presented, the conceptual framework is presented as a starting point for understanding this particular aspect of the psychology of natural disasters.« less

Ethical arguments relevant to the use of GM crops.

PubMed

Weale, Albert

2010-11-30

The Nuffield Council on Bioethics (NCOB) has published two reports (1999 and 2004) on the social and ethical issues involved in the use of genetically modified crops. This presentation summarises their core ethical arguments. Five sets of ethical concerns have been raised about GM crops: potential harm to human health; potential damage to the environment; negative impact on traditional farming practice; excessive corporate dominance; and the 'unnaturalness' of the technology. The NCOB examined these claims in the light of the principle of general human welfare, the maintenance of human rights and the principle of justice. It concluded in relation to the issue of 'unnaturalness' that GM modification did not differ to such an extent from conventional breeding that it is in itself morally objectionable. In making an assessment of possible costs, benefits and risks, it was necessary to proceed on a case-by-case basis. However, the potential to bring about significant benefits in developing countries (improved nutrition, enhanced pest resistance, increased yields and new products) meant that there was an ethical obligation to explore these potential benefits responsibly, to contribute to the reduction of poverty, and improve food security and profitable agriculture in developing countries. NCOB held that these conclusions were consistent with any practical precautionary approach. In particular, in applying a precautionary approach the risks associated with the status quo need to be considered, as well as any risks inherent in the technology. These ethical requirements have implications for the governance of the technology, in particular mechanisms for enabling small-scale farmers to express their preferences for traits selected by plant breeders and mechanisms for the diffusion of risk-based evaluations. Copyright © 2010 Elsevier B.V. All rights reserved.

Reprint of: Cling film plastic wrap: An innovation for dead body packaging, preservation and transportation by first responders as a replacement for cadaver body bag in large scale disasters.

PubMed

Khoo, Lay See; Lai, Poh Soon; Saidin, Mohd Hilmi; Noor, Zahari; Mahmood, Mohd Shah

2018-07-01

Cadaver body bags are the conventional method to contain a human body or human remains, which includes the use for storage and transportation of the deceased at any crime scene or disaster scene. During disasters, most often than not, the first responders including the police will be equipped with cadaver body bags to do scene processing of human remains and collection of personal belongings at the disaster site. However, in an unanticipated large scale disasters involving hundreds and thousands of fatalities, cadaver body bags supplies may be scarce. The authors have therefore innovated the cling film plastic wrap as an alternative for the cadaver body bag used at the disaster site. The plastic wrap was tested on six different experimental subjects, i.e. both adult and child mannequins; body parts of the mannequin figure (arm and hand); a human adult subject and an unknown dead body. The strengths of the cling film plastic wrap are discussed in comparison with the cadaver body bag in the aspects of costing, weight, duration of the wrap, water and body fluid resistant properties, visibility and other advantages. An average savings of more than 5000% are noted for both adult body wrap and child body wrap compared to the cadaver body wrap. This simply means that the authors can either wrap 25 adult dead bodies or 80 children dead bodies with the cost of 1 cadaver body bag. The cling film plastic wrap has proven to have significant innovation impact for dead body management particularly by the first responders in large scale disasters. With proper handling of dead bodies, first responders can manage the dead with dignity and respect in an overwhelmed situation to facilitate the humanitarian victim identification process later. Copyright © 2018 Elsevier B.V. All rights reserved.

Cling film plastic wrap: An innovation for dead body packaging, preservation and transportation by first responders as a replacement for cadaver body bag in large scale disasters.

PubMed

Khoo, Lay See; Lai, Poh Soon; Saidin, Mohd Hilmi; Noor, Zahari; Mahmood, Mohd Shah

2018-04-01

Cadaver body bags are the conventional method to contain a human body or human remains, which includes the use for storage and transportation of the deceased at any crime scene or disaster scene. During disasters, most often than not, the first responders including the police will be equipped with cadaver body bags to do scene processing of human remains and collection of personal belongings at the disaster site. However, in an unanticipated large scale disasters involving hundreds and thousands of fatalities, cadaver body bags supplies may be scarce. The authors have therefore innovated the cling film plastic wrap as an alternative for the cadaver body bag used at the disaster site. The plastic wrap was tested on six different experimental subjects, i.e. both adult and child mannequins; body parts of the mannequin figure (arm and hand); a human adult subject and an unknown dead body. The strengths of the cling film plastic wrap are discussed in comparison with the cadaver body bag in the aspects of costing, weight, duration of the wrap, water and body fluid resistant properties, visibility and other advantages. An average savings of more than 5000% are noted for both adult body wrap and child body wrap compared to the cadaver body wrap. This simply means that the authors can either wrap 25 adult dead bodies or 80 children dead bodies with the cost of 1 cadaver body bag. The cling film plastic wrap has proven to have significant innovation impact for dead body management particularly by the first responders in large scale disasters. With proper handling of dead bodies, first responders can manage the dead with dignity and respect in an overwhelmed situation to facilitate the humanitarian victim identification process later. Copyright © 2018 Elsevier B.V. All rights reserved.

Natural disasters: Cities build their vulnerability

NASA Astrophysics Data System (ADS)

Jones, Bryan

2017-04-01

Tornadoes pose a significant threat across vast portions of the US. Now research suggests that growth in the human-built environment will be more influential than climate change in driving future disaster potential.

Enhanced Stability of DNA Nanostructures by Incorporation of Unnatural Base Pairs.

PubMed

Liu, Qing; Liu, Guocheng; Wang, Ting; Fu, Jing; Li, Rujiao; Song, Linlin; Wang, Zhen-Gang; Ding, Baoquan; Chen, Fei

2017-11-03

Self-assembled DNA nanostructures hold great promise in the fields of nanofabrication, biosensing and nanomedicine. However, the inherent low stability of the DNA double helices, formed by weak interactions, largely hinders the assembly and functions of DNA nanostructures. In this study, we redesigned and constructed a six-arm DNA junction by incorporation of the unnatural base pairs 5-Me-isoC/isoG and A/2-thioT into the double helices. They not only retained the structural integrity of the DNA nanostructure, but also showed enhanced thermal stability and resistance to T7 Exonuclease digestion. This research may expand the applications of DNA nanostructures in nanofabrication and biomedical fields, and furthermore, the genetic alphabet expansion with unnatural base pairs may enable us to construct more complicated and diversified self-assembled DNA nanostructures. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Companion Animals, Natural Disasters and the Law: An Australian Perspective.

PubMed

White, Steven

2012-08-27

This article examines the regulation of companion animal welfare during disasters, with some context provided by two recent major disaster events in Australia. Important general lessons for improved disaster management were identified in subsequent inquiries. However, the interests of companion animals continue to be inadequately addressed. This is because key assumptions underpinning disaster planning for companion animals-the primacy of human interests over animal interests and that individuals will properly address companion animal needs during times of disaster-are open to question. In particular these assumptions fail to recognise the inherent value of companion animals, underestimate the strong bond shared by some owners and their animals and, at the same time, overestimate the capacity of some owners to adequately meet the needs of their animals.

Disaster management as part of curriculum for undergraduate and postgraduate courses: The Symbiosis model

PubMed Central

Deshpande, Vijay

2011-01-01

From times immemorial disasters in some form or the other have been regularly visiting humankind and humans have been trying to manage these upheavals. Noah's arch is the first such endeavor. The United Nations declared 1990-1999 as International Decade for Disaster Reduction. The Indian Government passed the Disaster Management Act 2005. As a consequence of the Act, the National Disaster Management Authority was setup. All states were given the guide lines for disaster risk reduction. The objective of this article is to get a clearer picture of what various states, educational authorities and international bodies have done and what Symbiosis International University (SIU) has done so far. Inputs from various States of the Indian Union and neighboring countries were studied. The moot question that figured all the time was “Is there a conscious effort to include Disaster Management in the curricula of various courses at the college and university level” and what are the achievements. It was seen that the Central Board for Secondary Education with support from the Ministry of Home Affairs, Ministry of Human Resource Development and United Nations Development Project have incorporated DM, as part of its frontline curriculum. Most of the Universities in the disaster prone states have enunciated policies for including DM in the curriculum, but palpable results are still awaited. In the SIU, DM has been incorporated in the curriculum and is mandatory for all undergraduate and postgraduate courses. PMID:22412285

Disaster management as part of curriculum for undergraduate and postgraduate courses: The Symbiosis model.

PubMed

Deshpande, Vijay

2011-09-01

From times immemorial disasters in some form or the other have been regularly visiting humankind and humans have been trying to manage these upheavals. Noah's arch is the first such endeavor. The United Nations declared 1990-1999 as International Decade for Disaster Reduction. The Indian Government passed the Disaster Management Act 2005. As a consequence of the Act, the National Disaster Management Authority was setup. All states were given the guide lines for disaster risk reduction. The objective of this article is to get a clearer picture of what various states, educational authorities and international bodies have done and what Symbiosis International University (SIU) has done so far. Inputs from various States of the Indian Union and neighboring countries were studied. The moot question that figured all the time was "Is there a conscious effort to include Disaster Management in the curricula of various courses at the college and university level" and what are the achievements. It was seen that the Central Board for Secondary Education with support from the Ministry of Home Affairs, Ministry of Human Resource Development and United Nations Development Project have incorporated DM, as part of its frontline curriculum. Most of the Universities in the disaster prone states have enunciated policies for including DM in the curriculum, but palpable results are still awaited. In the SIU, DM has been incorporated in the curriculum and is mandatory for all undergraduate and postgraduate courses.

Challenges Encountered During the Veterinary Disaster Response: An Example from Chile

PubMed Central

Garde, Elena; Pérez, Guillermo Enrique; Acosta-Jamett, Gerardo; Bronsvoort, Barend Mark

2013-01-01

Simple Summary Disaster preparedness for companion animals has economic, social and welfare benefits, yet many countries continue to omit dogs and cats from their national and regional contingency planning. Responses therefore, are often chaotic, inefficient and uncoordinated, or absent altogether. Documented experiences in Chile contribute to the information supporting the inclusion of companion animals into locally relevant disaster plans. These plans serve to prepare communities and authorities, identify resources available, establish a chain of command, develop local priorities, and subsequently reduce the negative impacts on both human and animal communities. Abstract Large-scale disasters have immeasurable effects on human and animal communities. Evaluating and reporting on the response successes and difficulties encountered serves to improve existing preparedness documents and provide support to those in the process of developing plans. Although the majority of disasters occur in low and middle income nations, less than 1% of the disaster literature originates from these countries. This report describes a response to a disease outbreak in domestic dogs in Dichato, Chile following the 2010 earthquake/tsunami. With no national plan coordinating the companion animal response, there was a chaotic approach among animal welfare organizations towards rescue, diagnosis, treatment and record-keeping. Similar to the medical response following the 1985 earthquake near Santiago, we experienced problems within our own teams in maintenance of data integrity and protocol compliance. Loss of infrastructure added complications with transportation, communications and acquisition of supplies. Similar challenges likely occur in most disasters, but can be reduced through pro-active planning at national and local levels. There is sufficient information to support the human and animal welfare benefits of including companion animals in national planning, and lessons learned through this and other experiences can assist planners in the development of comprehensive and locally relevant contingency plans. PMID:26479753

Computational Psychometrics for Modeling System Dynamics during Stressful Disasters

PubMed Central

Cipresso, Pietro; Bessi, Alessandro; Colombo, Desirée; Pedroli, Elisa; Riva, Giuseppe

2017-01-01

Disasters can be very stressful events. However, computational models of stress require data that might be very difficult to collect during disasters. Moreover, personal experiences are not repeatable, so it is not possible to collect bottom-up information when building a coherent model. To overcome these problems, we propose the use of computational models and virtual reality integration to recreate disaster situations, while examining possible dynamics in order to understand human behavior and relative consequences. By providing realistic parameters associated with disaster situations, computational scientists can work more closely with emergency responders to improve the quality of interventions in the future. PMID:28861026

Acting on an environmental health disaster: the case of the Aral Sea.

PubMed

Small, I; van der Meer, J; Upshur, R E

2001-06-01

The Aral Sea area in Central Asia has been encountering one of the world's greatest environmental disasters for more than 15 years. During that time, despite many assessments and millions of dollars spent by large, multinational organizations, little has changed. The 5 million people living in this neglected and virtually unknown part of the world are suffering not only from an environmental catastrophe that has no easy solutions but also from a litany of health problems. The region is often dismissed as a chronic problem where nothing positive can be achieved. Within this complicated context, Medecins Sans Frontieres, winner of the Nobel Peace Prize in 1999, is actively trying to assess the impact of the environmental disaster on human health to help the people who live in the Aral Sea area cope with their environment. Medecins Sans Frontieres has combined a direct medical program to improve the health of the population while conducting operational research to gain a better understanding of the relationship between the environmental disaster and human health outcomes. In this paper we explore the health situation of the region and the broader policy context in which it is situated, and present some ideas that could potentially be applied to many other places in the world that are caught up in environmental and human health disasters.

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.

PubMed

Betz, Karin; Malyshev, Denis A; Lavergne, Thomas; Welte, Wolfram; Diederichs, Kay; Dwyer, Tammy J; Ordoukhanian, Phillip; Romesberg, Floyd E; Marx, Andreas

2012-07-01

Many candidate unnatural DNA base pairs have been developed, but some of the best-replicated pairs adopt intercalated structures in free DNA that are difficult to reconcile with known mechanisms of polymerase recognition. Here we present crystal structures of KlenTaq DNA polymerase at different stages of replication for one such pair, dNaM-d5SICS, and show that efficient replication results from the polymerase itself, inducing the required natural-like structure.

Genetically encoded fluorescent coumarin amino acids

DOEpatents

Wang, Jiangyun; Xie, Jianming; Schultz, Peter G.

2010-10-05

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the coumarin unnatural amino acid L-(7-hydroxycoumarin-4-yl) ethylglycine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine and related translation systems.

Genetically encoded fluorescent coumarin amino acids

DOEpatents

Wang, Jiangyun [San Diego, CA; Xie, Jianming [San Diego, CA; Schultz, Peter G [La Jolla, CA

2012-06-05

The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the coumarin unnatural amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid L-(7-hydroxycoumarin-4-yl)ethylglycine and related translation systems.

Post-ExSELEX stabilization of an unnatural-base DNA aptamer targeting VEGF165 toward pharmaceutical applications.

PubMed

Kimoto, Michiko; Nakamura, Mana; Hirao, Ichiro

2016-09-06

A new technology, genetic alphabet expansion using artificial bases (unnatural bases), has created high-affinity DNA ligands (aptamers) that specifically bind to target proteins by ExSELEX (genetic alphabet Expansion for Systematic Evolution of Ligands by EXponential enrichment). We recently found that the unnatural-base DNA aptamers can be stabilized against nucleases, by introducing an extraordinarily stable, unique hairpin DNA (mini-hairpin DNA) and by reinforcing the stem region with G-C pairs. Here, to establish this aptamer generation method, we examined the stabilization of a high-affinity anti-VEGF165 unnatural-base DNA aptamer. The stabilized aptamers displayed significantly increased thermal and nuclease stabilities, and furthermore, exhibited higher affinity to the target. As compared to the well-known anti-VEGF165 RNA aptamer, pegaptanib (Macugen), our aptamers did not require calcium ions for binding to VEGF165 Biological experiments using cultured cells revealed that our stabilized aptamers efficiently inhibited the interaction between VEGF165 and its receptor, with the same or slightly higher efficiency than that of the pegaptanib RNA aptamer. The development of cost-effective and calcium ion-independent high-affinity anti-VEGF165 DNA aptamers encourages further progress in diagnostic and therapeutic applications. In addition, the stabilization process provided additional information about the key elements required for aptamer binding to VEGF165. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

High-Yield, Zero-Leakage Expression System with a Translational Switch Using Site-Specific Unnatural Amino Acid Incorporation

PubMed Central

Minaba, Masaomi

2014-01-01

Synthetic biologists construct complex biological circuits by combinations of various genetic parts. Many genetic parts that are orthogonal to one another and are independent of existing cellular processes would be ideal for use in synthetic biology. However, our toolbox is still limited with respect to the bacterium Escherichia coli, which is important for both research and industrial use. The site-specific incorporation of unnatural amino acids is a technique that incorporates unnatural amino acids into proteins using a modified exogenous aminoacyl-tRNA synthetase/tRNA pair that is orthogonal to any native pairs in a host and is independent from other cellular functions. Focusing on the orthogonality and independency that are suitable for the genetic parts, we designed novel AND gate and translational switches using the unnatural amino acid 3-iodo-l-tyrosine incorporation system in E. coli. A translational switch was turned on after addition of 3-iodo-l-tyrosine in the culture medium within minutes and allowed tuning of switchability and translational efficiency. As an application, we also constructed a gene expression system that produced large amounts of proteins under induction conditions and exhibited zero-leakage expression under repression conditions. Similar translational switches are expected to be applicable also for eukaryotes such as yeasts, nematodes, insects, mammalian cells, and plants. PMID:24375139

Steric and Thermodynamic Limits of Design for the Incorporation of Large UnNatural Amino Acids in Aminoacyl-tRNA Synthetase Enzymes

PubMed Central

Armen, Roger S.; Schiller, Stefan M.; Brooks, Charles L.

2015-01-01

Orthogonal aminoacyl-tRNA synthetase/tRNA pairs from archaea have been evolved to facilitate site specific in vivo incorporation of unnatural amino acids into proteins in Escherichia coli. Using this approach, unnatural amino acids have been successfully incorporated with high translational efficiency and fidelity. In this study, CHARMM-based molecular docking and free energy calculations were used to evaluate rational design of specific protein-ligand interactions for aminoacyl-tRNA synthetases. A series of novel unnatural amino acid ligands were docked into the p-benzoyl-L-phenylalanine tRNA synthetase, which revealed that the binding pocket of the enzyme does not provide sufficient space for significantly larger ligands. Specific binding site residues were mutated to alanine to create additional space to accommodate larger target ligands, and then mutations were introduced to improve binding free energy. This approach was used to redesign binding sites for several different target ligands, which were then tested against the standard 20 amino acids to verify target specificity. Only the synthetase designed to bind Man-α-O-Tyr was predicted to be sufficiently selective for the target ligand and also thermodynamically stable. Our study suggests that extensive redesign of the tRNA synthatase binding pocket for large bulky ligands may be quite thermodynamically unfavorable. PMID:20310065

Color constancy influenced by unnatural spatial structure.

PubMed

Mizokami, Yoko; Yaguchi, Hirohisa

2014-04-01

The recognition of spatial structures is important for color constancy because we cannot identify an object's color under different illuminations without knowing which space it is in and how that space is illuminated. To show the importance of the natural structure of environments on color constancy, we investigated the way in which color appearance was affected by unnatural viewing conditions in which a spatial structure was distorted. Observers judged the color of a test patch placed in the center of a small room illuminated by white or reddish lights, as well as two rooms illuminated by white and reddish light, respectively. In the natural viewing condition, an observer saw the room(s) through a viewing window, whereas in an unnatural viewing condition, the scene structure was scrambled by a kaleidoscope-type viewing box. Results of single room condition with one illuminant color showed little difference in color constancy between the two viewing conditions. However, it decreased in the two-rooms condition with a more complex arrangement of space and illumination. The patch's appearance under the unnatural viewing condition was more influenced by simultaneous contrast than its appearance under the natural viewing condition. It also appears that color appearance under white illumination is more stable compared to that under reddish illumination. These findings suggest that natural spatial structure plays an important role for color constancy in a complex environment.

Using disaster exercises to determine staff educational needs and improve disaster outcomes in rural hospitals: the role of the nursing professional development educator.

PubMed

Anderson, Denise A

2012-06-01

Using human potential in rural hospitals is vital to successful outcomes when handling disasters. Nursing professional development educators provide leadership and guiding vision during a time when few educational research studies demonstrate how to do so. This article explains the role of the rural nursing professional development educator as a disaster preparedness educator, facilitator, collaborator, researcher, and leader, using the American Nurses Association's Nursing Professional Development: Scope and Standards of Practice. Copyright 2012, SLACK Incorporated.

Conducting Science in Disasters: Recommendations from the NIEHS Working Group for Special IRB Considerations in the Review of Disaster Related Research.

PubMed

Packenham, Joan P; Rosselli, Richard T; Ramsey, Steve K; Taylor, Holly A; Fothergill, Alice; Slutsman, Julia; Miller, Aubrey

2017-09-25

Research involving human subjects after public health emergencies and disasters may pose ethical challenges. These challenges may include concerns about the vulnerability of prospective disaster research participants, increased research burden among disaster survivors approached by multiple research teams, and potentially reduced standards in the ethical review of research by institutional review boards (IRBs) due to the rush to enter the disaster field. The NIEHS Best Practices Working Group for Special IRB Considerations in the Review of Disaster Related Research was formed to identify and address ethical and regulatory challenges associated with the review of disaster research. The working group consists of a diverse collection of disaster research stakeholders across a broad spectrum of disciplines. The working group convened in July 2016 to identify recommendations that are instrumental in preparing IRBs to review protocols related to public health emergencies and disasters. The meeting included formative didactic presentations and facilitated breakout discussions using disaster-related case studies. Major thematic elements from these discussions were collected and documented into 15 working group recommendations, summarized in this article, that address topics such as IRB disaster preparedness activities, informed consent, vulnerable populations, confidentiality, participant burden, disaster research response integration and training, IRB roles/responsibilities, community engagement, and dissemination of disaster research results. https://doi.org/10.1289/EHP2378.

Conducting Science in Disasters: Recommendations from the NIEHS Working Group for Special IRB Considerations in the Review of Disaster Related Research

PubMed Central

Rosselli, Richard T.; Ramsey, Steve K.; Taylor, Holly A.; Fothergill, Alice; Slutsman, Julia; Miller, Aubrey

2017-01-01

Summary: Research involving human subjects after public health emergencies and disasters may pose ethical challenges. These challenges may include concerns about the vulnerability of prospective disaster research participants, increased research burden among disaster survivors approached by multiple research teams, and potentially reduced standards in the ethical review of research by institutional review boards (IRBs) due to the rush to enter the disaster field. The NIEHS Best Practices Working Group for Special IRB Considerations in the Review of Disaster Related Research was formed to identify and address ethical and regulatory challenges associated with the review of disaster research. The working group consists of a diverse collection of disaster research stakeholders across a broad spectrum of disciplines. The working group convened in July 2016 to identify recommendations that are instrumental in preparing IRBs to review protocols related to public health emergencies and disasters. The meeting included formative didactic presentations and facilitated breakout discussions using disaster-related case studies. Major thematic elements from these discussions were collected and documented into 15 working group recommendations, summarized in this article, that address topics such as IRB disaster preparedness activities, informed consent, vulnerable populations, confidentiality, participant burden, disaster research response integration and training, IRB roles/responsibilities, community engagement, and dissemination of disaster research results. https://doi.org/10.1289/EHP2378 PMID:28949918

[The analysis of the course of pregnancy, delivery and postpartum among women touched by flood disaster in Kotlin Kłodzki in July 1997].

PubMed

Neuberg, M; Pawłosek, W; Lopuszański, M; Neuberg, J

1998-12-01

A natural disaster has been defined as a disruption of human ecology that exceeds the capacity of the community to function normally. Little is known about the influence of flood disaster on reproductive outcomes. This study reviews perinatal medical problems in pregnant women during the flood disaster from Kłodzko Region in July 1997. 47 pregnant women were investigated which injured from the flood disaster. We observed a psychosocial stress in this women. A control random group consists of 100 pregnant women in 1996. Reproductive outcomes include pregnancy loss in 55.3% and other severe disorders: premature delivery, missed abortion, birth asphyxia, premature rupture of membranes, intrauterine growth retardation. Psychosocial stress observed during the flood disaster cause many perinatal complications and pregnancy loss. Intensive perinatal medical care must usually be provided from outside the disaster area.

Three decades of disasters: a review of disaster-specific literature from 1977-2009.

PubMed

Smith, Erin; Wasiak, Jason; Sen, Ayan; Archer, Frank; Burkle, Frederick M

2009-01-01

The potential for disasters exists in all communities. To mitigate the potential catastrophes that confront humanity in the new millennium, an evidence-based approach to disaster management is required urgently. This study moves toward such an evidence-based approach by identifying peer-reviewed publications following a range of disasters and events over the past three decades. Peer-reviewed, event-specific literature was identified using a comprehensive search of the electronically indexed database, MEDLINE (1956-January 2009). An extended comprehensive search was conducted for one event to compare the event-specific literature indexed in MEDLINE to other electronic databases (EMBASE, CINAHL, AMED, CENTRAL, Psych Info, Maternity and Infant Care, EBM Reviews). Following 25 individual disasters or overwhelming crises, a total of 2,098 peer-reviewed, event-specific publications were published in 789 journals (652 publications following disasters/events caused by natural hazards, 966 following human-made/technological disasters/events, and 480 following conflict/complex humanitarian events).The event with the greatest number of peer-reviewed, event-specific publications was the 11 September 2001 terrorist attacks (686 publications). Prehospital and Disaster Medicine published the greatest number of peer-reviewed, event-specific publications (54), followed by Journal of Traumatic Stress (42), Military Medicine (40), and Psychiatric Services (40). The primary topics of event-specific publications were mental health, medical health, and response. When an extended, comprehensive search was conducted for one event, 75% of all peer-reviewed, event-specific publications were indexed in MEDLINE. A broad range of multi-disciplinary journals publish peer reviewed, event-specific publications. While the majority of peer-reviewed, event-specific literature is indexed in MEDLINE, comprehensive search strategies should include EMBASE to increase yield.

Supply Chain Management in Disaster Response

DOT National Transportation Integrated Search

2009-09-01

In todays society that disasters seem to be striking all corners of the United States and the globe, the importance of emergency management is undeniable. Much human loss and unnecessary destruction of infrastructure can be avoided with more fores...

Femtomolar Ln(III) affinity in peptide-based ligands containing unnatural chelating amino acids.

PubMed

Niedźwiecka, Agnieszka; Cisnetti, Federico; Lebrun, Colette; Delangle, Pascale

2012-05-07

The incorporation of unnatural chelating amino acids in short peptide sequences leads to lanthanide-binding peptides with a higher stability than sequences built exclusively from natural residues. In particular, the hexadentate peptide P(22), which incorporates two unnatural amino acids Ada(2) with aminodiacetate chelating arms, showed picomolar affinity for Tb(3+). To design peptides with higher denticity, expected to show higher affinity for Ln(3+), we synthesized the novel unnatural amino acid Ed3a(2) which carries an ethylenediamine triacetate side-chain and affords a pentadentate coordination site. The synthesis of the derivative Fmoc-Ed3a(2)(tBu)(3)-OH, with appropriate protecting groups for direct use in the solid phase peptide synthesis (Fmoc strategy), is described. The two high denticity peptides P(HD2) (Ac-Trp-Ed3a(2)-Pro-Gly-Ada(2)-Gly-NH(2)) and P(HD5) (Ac-Trp-Ada(2)-Pro-Gly-Ed3a(2)-Gly-NH(2)) led to octadentate Tb(3+) complexes with femtomolar stability in water. The position of the high denticity amino acid Ed3a(2) in the hexapeptide sequence appears to be critical for the control of the metal complex speciation. Whereas P(HD5) promotes the formation of polymetallic species in excess of Ln(3+), P(HD2) forms exclusively the mononuclear complex. The octadentate coordination of Tb(3+) by both P(HD) leads to total dehydration of the metal ion in the mononuclear complexes with long luminescence lifetimes (>2 ms). Hence, we demonstrated that unnatural amino acids carrying polyaminocarboxylate side-chains are interesting building blocks to design high affinity Ln-binding peptides. In particular the novel peptide P(HD2) forms a unique octadentate Tb(3+) complex with femtomolar stability in water and an improvement of the luminescence properties with respect to the trisaquo TbP(22) complex by a factor of 4.

The cultural politics of mining and natural disaster in Indonesia: by fire and sword.

PubMed

Lewis, Jeff; Lewis, Belinda

2017-01-01

Natural disasters are inevitably the outcome of cultural agonisms. The cultural politics of natural disasters are shaped by competing claims and conceptions of 'nature'. Recent disasters in Indonesia are directly linked to these contending conceptions and the ways in which different social groups imagine risk and reward. The Sidoarjo volcanic mudflow of 2006 represents a volatile and violent exemplar of contending cultural and economic claims. Like other disasters in Indonesia and elsewhere in the developing world, this 'natural' disaster is characterised by differing conceptions of 'nature' as cultural tradition, divine force, and natural resource. A new extractive project in East Java is exhibiting similar economic and cultural agonisms, particularly around the notion of development, environment, self-determination, and tradition. This paper examines the 'disputes over meaning' associated with natural disasters in contemporary societies, and the ways in which they are related to human culture, social organisation, and hierarchical systems of violence. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

Who dares to join a parabolic flight?

NASA Astrophysics Data System (ADS)

Montag, Christian; Zander, Tina; Schneider, Stefan

2016-12-01

Parabolic flights represent an important tool in space research to investigate zero gravity on airplanes. Research on these flights often target psychological and biological processes in humans to investigate if and how we can adapt to this unique environment. This research is costly, hard to conduct and clearly heavily relies on humans participating in experiments in this (unnatural) situation. The present study investigated N =66 participants and N =66 matched control persons to study if participants in such experimental flights differ in terms of their personality traits from non-parabonauts. The main finding of this study demonstrates that parabonauts score significantly lower on harm avoidance, a trait closely linked to being anxious. As anxious humans differ from non-anxious humans in their biology, the present observations need to be taken into account when aiming at the generalizability of psychobiological research findings conducted in zero gravity on parabolic flights.

[Physical restraints and gagging in unnatural death].

PubMed

Grellner, W; Madea, B

1993-01-01

Practices of binding and gagging can be found in different types of unnatural death; three case reports concerning fatal autoeroticism, suicide and homicide are presented. In such cases investigations are usually concentrated on the question whether binding and gagging could be carried out by the persons themselves. Loosely bound final loops, especially of the hands, missing local haemorrhages and the discovery of binding instructions support the assumption of self-binding. Accompanying injuries and the entire situation must be taken into special consideration.

Synthesis of Natural and Unnatural Cyclooligomeric Depsipeptides Enabled by Flow Chemistry

PubMed Central

Lücke, Daniel; Dalton, Toryn; Ley, Steven V.

2016-01-01

Abstract Flow chemistry has been successfully integrated into the synthesis of a series of cyclooligomeric depsipeptides of three different ring sizes including the natural products beauvericin (1 a), bassianolide (2 b) and enniatin C (1 b). A reliable flow chemistry protocol was established for the coupling and macrocyclisation to form challenging N‐methylated amides. This flexible approach has allowed the rapid synthesis of both natural and unnatural depsipeptides in high yields, enabling further exploration of their promising biological activity. PMID:26844421

Zonation of High Disaster Potential Communities for Remote Mountainous Areas in Southern Taiwan

NASA Astrophysics Data System (ADS)

Chen, Yie-Ruey; Tsai, Kuang-Jung; Chang, Chwen-Ming; Chen, Jing-Wen; Chiang, Jie-Lun; Lu, Yi-Ching; Tsai, Hui-Wen

2017-04-01

About three-quarters of Taiwan are covered by hillside areas. Most of the hillside regions in Taiwan are sedimentary and metamorphic rocks which are fragile and highly weathered. In recent years, human development coupled with the global impact of extreme weather, typhoons and heavy rains have caused the landslide disasters and leaded to human causalities and properties loss. The landslides also endanger the major public works and almost make the overall industrial economic development and transport path overshadowed by disasters. Therefore, this research assesses the exploration of landslide potential analysis and zonation of high disaster potential communities for remote mountainous areas in southern Taiwan. In this study, the time series of disaster records and land change of remote mountainous areas in southern Taiwan are collected using techniques of interpretation from satellite images corresponding to multi-year and multi-rainfall events. To quantify the slope hazards, we adopt statistical analysis model to analyze massive data of slope disasters and explore the variance, difference and trend of influence factors of hillside disaster; establish the disaster potential analysis model under the climate change and construct the threshold of disaster. Through analysis results of disaster potential assessment, the settlement distribution with high-risk hazard potential of study area is drawn with geographic information system. Results of image classification show that the values of coefficient of agreement for different time periods are at high level. Compared with the historical disaster records of research areas, the accuracy of predicted landslide potential is in reasonable confidence level. The spatial distribution of landslide depends on the interaction of rainfall patterns, slope and elevation of the research area. The results also show that the number and scale of secondary landslide sites are much larger than those of new landslide sites after rainfall. The greater the slope land disturbance, the more likely the scale of secondary landslide uprises. The results of the map for the zonation of high-disaster potential communities can be a useful reference for the government to plan strategies on adaptation to climate change for remote mountainous communities in southern Taiwan.

Stimulating Creativity by Integrating Research and Teaching Across the Academic Disciplines

NASA Astrophysics Data System (ADS)

Taylor, Richard

2013-03-01

Creativity is a human adventure fueled by the process of exploration. But how do we explore our intellectual interests? In this talk, I'll propose that we seek out our creative opportunities using an inherent natural process. This process might, therefore, exploit search strategies found across diverse natural systems - ranging from the way animals forage for food to the way the human eye locates information embedded within complex patterns. The symbolic significance of this hypothesis lies in its call for educational institutes to provide environments that encourage our natural explorations rather those that stamp restrictive, artificial `order' on the process. To make my case, I'll review some of my own research trajectories followed during my RCSA Cottrell Scholarship at the University of Oregon (UO). My first conclusion will be that it is fundamentally unnatural to declare divides across disciplines. In particular, the infamous `art-science divide' is not a consequence of our natural creative searches but instead arises from our practical inability to accommodate the rapid drive toward academic specialization. Secondly, divides between research and teaching activities are equally unnatural - both endeavors are driven by the same creative strategy and are intertwined within the same natural process. This applies equally to the experiences of professors and students. I will end with specific success stories at the UO. These include a NSF IGERT project (focused on accelerating students' transitions from classroom to research experiences) and a collaboration between architects and professors to design a building (the recently opened Lewis Integrative Science Building) that encourages daily encounters between students and professors across research disciplines.

Global climate changes, natural disasters, and travel health risks.

PubMed

Diaz, James H

2006-01-01

Whether the result of cyclical atmospheric changes, anthropogenic activities, or combinations of both, authorities now agree that the earth is warming from a variety of climatic effects, including the cascading effects of greenhouse gas emissions to support human activities. To date, most reports of the public health outcomes of global warming have been anecdotal and retrospective in design and have focused on heat stroke deaths following heat waves, drowning deaths in floods and tsunamis, and mosquito-borne infectious disease outbreaks following tropical storms and cyclones. Accurate predictions of the true public health outcomes of global climate change are confounded by several effect modifiers including human acclimatization and adaptation, the contributions of natural climatic changes, and many conflicting atmospheric models of climate change. Nevertheless, temporal relationships between environmental factors and human health outcomes have been identified and may be used as criteria to judge the causality of associations between the human health outcomes of climate changes and climate-driven natural disasters. Travel medicine physicians are obligated to educate their patients about the known public health outcomes of climate changes, about the disease and injury risk factors their patients may face from climate-spawned natural disasters, and about the best preventive measures to reduce infectious diseases and injuries following natural disasters throughout the world.

Managing the natural disasters from space technology inputs

NASA Astrophysics Data System (ADS)

Jayaraman, V.; Chandrasekhar, M. G.; Rao, U. R.

1997-01-01

Natural disasters, whether of meteorological origin such as Cyclones, Floods, Tornadoes and Droughts or of having geological nature such as earthquakes and volcanoes, are well known for their devastating impacts on human life, economy and environment. With tropical climate and unstable land forms, coupled with high population density, poverty, illiteracy and lack of infrastructure development, developing countries are more vulnerable to suffer from the damaging potential of such disasters. Though it is almost impossible to completely neutralise the damage due to these disasters, it is, however possible to (i) minimise the potential risks by developing disaster early warning strategies (ii) prepare developmental plans to provide resilience to such disasters, (iii) mobilize resources including communication and telemedicinal services and (iv) to help in rehabilitation and post-disaster reconstruction. Space borne platforms have demonstrated their capability in efficient disaster management. While communication satellites help in disaster warning, relief mobilisation and telemedicinal support, Earth observation satellites provide the basic support in pre-disaster preparedness programmes, in-disaster response and monitoring activities, and post-disaster reconstruction. The paper examines the information requirements for disaster risk management, assess developing country capabilities for building the necessary decision support systems, and evaluate the role of satellite remote sensing. It describes several examples of initiatives from developing countries in their attempt to evolve a suitable strategy for disaster preparedness and operational framework for the disaster management Using remote sensing data in conjunction with other collateral information. It concludes with suggestions and recommendations to establish a worldwide network of necessary space and ground segments towards strengthening the technological capabilities for disaster management and mitigation.

Navigating a social world with robot partners: A quantitative cartography of the Uncanny Valley.

PubMed

Mathur, Maya B; Reichling, David B

2016-01-01

Android robots are entering human social life. However, human-robot interactions may be complicated by a hypothetical Uncanny Valley (UV) in which imperfect human-likeness provokes dislike. Previous investigations using unnaturally blended images reported inconsistent UV effects. We demonstrate an UV in subjects' explicit ratings of likability for a large, objectively chosen sample of 80 real-world robot faces and a complementary controlled set of edited faces. An "investment game" showed that the UV penetrated even more deeply to influence subjects' implicit decisions concerning robots' social trustworthiness, and that these fundamental social decisions depend on subtle cues of facial expression that are also used to judge humans. Preliminary evidence suggests category confusion may occur in the UV but does not mediate the likability effect. These findings suggest that while classic elements of human social psychology govern human-robot social interaction, robust UV effects pose a formidable android-specific problem. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

Artificial gametes, the unnatural and the artefactual.

PubMed

Smajdor, Anna; Cutas, Daniela; Takala, Tuija

2018-06-01

In debates on the ethics of artificial gametes, concepts of naturalness have been used in a number of different ways. Some have argued that the unnaturalness of artificial gametes means that it is unacceptable to use them in fertility treatments. Others have suggested that artificial gametes are no less natural than many other tissues or processes in common medical use. We suggest that establishing the naturalness or unnaturalness of artificial gametes is unlikely to provide easy answers as to the acceptability of using them in fertility medicine. However, we also suggest that we should be cautious about repudiating any relationship between nature and moral evaluation. The property of being natural or man-made may not per se tell us anything about an entity's moral status, but it has an important impact on the moral relationship between the creator and the created organism. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Antimicrobial peptides containing unnatural amino acid exhibit potent bactericidal activity against ESKAPE pathogens.

PubMed

Hicks, R P; Abercrombie, J J; Wong, R K; Leung, K P

2013-01-01

A series of 36 synthetic antimicrobial peptides containing unnatural amino acids were screened to determine their effectiveness to treat Enterococcus faecium, Staphylococcus aureus, Klebsiella pnemoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species (ESKAPE) pathogens, which are known to commonly infect chronic wounds. The primary amino acid sequences of these peptides incorporate either three or six dipeptide units consisting of the unnatural amino acids Tetrahydroisoquinolinecarboxylic acid (Tic) and Octahydroindolecarboxylic acid (Oic). The Tic-Oic dipeptide units are separated by SPACER amino acids with specific physicochemical properties that control how these peptides interact with bacterial cell membranes of different chemical compositions. These peptides exhibited minimum inhibitory concentrations (MIC) against these pathogens in the range from >100 to 6.25 μg/mL. The observed diversity of MIC values for these peptides against the various bacterial strains are consistent with our hypothesis that the complementarity of the physicochemical properties of the peptide and the lipid of the bacteria's cell membrane determines the resulting antibacterial activity of the peptide. Published by Elsevier Ltd.

Resonances in positron-potassium (e +-K) system with natural and unnatural parities

NASA Astrophysics Data System (ADS)

Umair, M.; Jonsell, S.

2016-01-01

We present an investigation of resonances with natural and unnatural parities in the positron-potassium system using the complex scaling method. A model potential is used to represent the interaction between the core and the valence electron. Explicitly correlated Gaussian wave functions are used to represent the correlation effects between the valence electron, the positron and the K+ core. Resonance energies and widths for two partial waves (S- and P-wave) below the {{K}}(4p,5 s,5p,4 d,4f) excitation thresholds and positronium n = 2 formation threshold are calculated for natural parity. Resonance states for P e below the {{K}}(4d) excitation threshold and positronium n = 2, 3 formation thresholds are calculated for unnatural parity which has not been previously reported. Below both positronium thresholds we have found a dipole series of resonances, with binding energies scaling in good agreement with exceptions from an analytical calculation. The present results are compared with those in the literature.

Dynamics of internal pore opening in KV channels probed by a fluorescent unnatural amino acid

PubMed Central

Kalstrup, Tanja; Blunck, Rikard

2013-01-01

Atomic-scale models on the gating mechanism of voltage-gated potassium channels (Kv) are based on linear interpolations between static structures of their initial and final state derived from crystallography and molecular dynamics simulations, and, thus, lack dynamic structural information. The lack of information on dynamics and intermediate states makes it difficult to associate the structural with the dynamic functional data obtained with electrophysiology. Although voltage-clamp fluorometry fills this gap, it is limited to sites extracellularly accessible, when the key region for gating is located at the cytosolic side of the channels. Here, we solved this problem by performing voltage-clamp fluorometry with a fluorescent unnatural amino acid. By using an orthogonal tRNA-synthetase pair, the fluorescent unnatural amino acid was incorporated in the Shaker voltage-gated potassium channel at key regions that were previously inaccessible. Thus, we defined which parts act independently and which parts act cooperatively and found pore opening to occur in two sequential transitions. PMID:23630265

Disaster mental health services following the 1995 Oklahoma City bombing: modifying approaches to address terrorism.

PubMed

Pfefferbaum, Betty; North, Carol S; Flynn, Brian W; Norris, Fran H; DeMartino, Robert

2002-08-01

How did the 1995 Oklahoma City bombing differ from prior disasters and what implications did it have for disaster mental health services and service delivery? The federal disaster mental health approach in this country developed largely out of experiences with natural disasters. The 1995 Oklahoma City bombing differed in several important ways, including the large number of human casualties, higher rates of psychopathology, and an extended period of concern due to the criminal investigation and trials, which suggested the need to consider modifications in the program. Outreach was extensive, but psychiatric morbidity of direct victims was greater than that of victims of natural disasters, emphasizing the need for attention to the triage and referral process. Other concerns that warrant consideration include practices related to record keeping and program evaluation.

Onboard Radar Processor Development for Disaster Response

NASA Technical Reports Server (NTRS)

Lou, Yunling; Clark, Duane; Hensley, Scott; Jones, Cathleen; Marks, Phillip; Muellerschoen, Ron; Wang, Charles C.

2013-01-01

Natural hazards often result in significant loss of human lives, economic assets and productivity as well as significant damage to the ecosystem. Scientists have reported more frequent and intense natural disasters in recent years, which may well be attributed to climate change. Many of the disaster response efforts were hampered by lack of up-to-date knowledge of the state of the affected areas because damaged infrastructure rendered the areas inaccessible. Radar remote sensing is playing an increasingly critical role in providing timely information to disaster response agencies due to the increasing fidelity and availability of geospatial information products.

Environmental Change, Natural Disasters and Stability in Central America and the Caribbean (CSL Issue Paper, Volume 5-10, September 2010)

DTIC Science & Technology

2010-09-01

the climate situation is wetter and more vulnerable to hurricane events. Environmental impacts also influence human health, biodiversity , and...frequency of more severe hurricanes, floods, and droughts. The detrimental manmade disasters in the region include deforestation , land use changes...to mitigating the effects of these issues that limit the spread and severity of disasters and preserve the resource base upon which nation state

Building Population Resilience to Terror Attacks: Unlearned Lessons from Military and Civilian Experience

DTIC Science & Technology

2006-11-01

disaster. Recent work by Anthony Mawson highlights the marked disparity between how people are presumed to behave during disasters and their actual...recklessly flee to safety, there is little evidence to support this belief. Building Population Resilience to Terror Attacks . . . 9 Mawson finds that... Mawson goes on to outline four corollaries to these mistaken assumptions that reflect research on human behavior in times of crisis or disaster

Social response to technological disaster: the accident at Three Mile Island

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richardson, B.B.

1984-01-01

Until recently the sociological study of man environment relations under extreme circumstances has been restricted to natural hazards (e.g., floods, hurricanes, tornadoes). Technological disasters are becoming more commonplace (e.g., Times Beach, MO, Love Canal, TMI-2) and are growing as potential sources of impact upon human populations. However, theory regarding the social impact of such disasters has not been developed. While research on natural disasters is in part applicable to technological disasters, theory adapted from environmental sociology and psychology are also utilized to develop a theory of social response to extreme environmental events produced by technology. Hypotheses are developed in themore » form of an empirically testable model based on the literature reviewed.« less

Mediterranean Storms: An Integrated Approach of Risk Management

NASA Astrophysics Data System (ADS)

Karageorgou, H.; Riza, E.; Linos, A.; Papanikolaou, D.

2010-09-01

Disaster by UN definition is "a serious disruption of the functioning of a community or a society, involving widespread human, material, economic, or environmental losses and impacts, which exceeds the ability of the affected community or society to cope using only its own resources". Mediterranean storms induce flash floods caused by excessive amounts of rainfall within a short lasting period of time. The intensity and duration of precipitation, region geomorphology, urbanization and different governmental emergency management structures trigger different consequences between Mediterranean countries. The integrated approach in management of storm risk represents a holistic perspective including interactions between government, science and technology institutions, developing agencies, private sector, NGOs and public. Local authorities and national government are responsible for the design, preparation and decision on storm risk management policies and strategies considering scientific risk identifying, assessing and understanding. Efficient governance management requires satisfied response to early warning systems, functionality of the affected systems upon which society depends and appropriate focus on variable interest, beliefs, values and ideologies between social groups. Also an appropriate balancing of benefits and costs in an efficient and equitable manner is important for the governance risk management. Natural sciences in corporation with the engineering science have developed effective early prediction, warning and monitoring systems on storm and flood risk. The health sciences use prediction systems for health related hazards and consequences and the social sciences research estimates the human resilience during disasters and the factors which affect and determine the human behavior. Also social sciences survey the response of public to early warning messages, the appropriate communicative methods to distributing messages and mechanisms to improve public response. The available and applied science and technology in prediction and early warning systems rely on the close collaboration between scientists and policy makers to achieve effective disaster prevention of human life and mitigation of damages. Developing agencies approach risk management as an integral part of development and encourage activities and measures to reduce the exposure and vulnerability to natural hazards through early warning systems, building codes, land use plans and disaster sensitive development plans. The human settlement and investment in high risk floodplains place greater numbers of people and economic assets in danger of being affected by storms and floods. Disasters and development are highly inter-related. Recurrent disasters and frequent localized disasters erode development and conversely the development processes can reduce disaster risk, or create new risks. The private sector participation in risk reduction efforts can help local communities mitigate disasters and increases the benefits of the businesses. The private insurance sector is highly involved in the prevention of disaster caused by natural hazards especially storms and floods. The collaboration between academic community and the insurance sector indicates the linkages between the mutual insurance actions and risk culture. Also tourism industry and private critical infrastructure sector get involved in prevention measures and activities against storm and flood risks to build sustainable functionality and keep public trust. NGOs focus on social, cultural, environmental, educational, or health issues in disaster management and their members are educated and experienced on their area of operations. The staff of local and national NGOs is familiar with culture, languages, governance structures, social networks, climate and geography of the affected area and holds a unique understanding of the specific problems of the affected population. Additionally, NGO’s operations do not suffer from bureaucracy and therefore are able to deploy on very short notice. The public awareness, behavior and response to disasters depend on the knowledge about the risk, the understanding of the information and the translation of what it means in their own particular circumstances. The majority of people judges the information to be credible and discusses the meaning of information with trusted family members, friends and colleagues to decide the next action. Well educated people, efficient management of previous experiences, successful communication methods and trust on government and authorities contribute towards efficient public response on disasters.

Why the poor pay with their lives: oil pipeline vandalisation, fires and human security in Nigeria.

PubMed

Onuoha, Freedom C

2009-07-01

Since its discovery in Nigeria in 1956 crude oil has been a source of mixed blessing to the country. It is believed to have generated enormous wealth, but it has also claimed a great many lives. Scholarly attention on the impact of oil on security in Nigeria has largely focused on internal conflicts rather than on how disasters associated with oil pipeline vandalisation have impacted on human security in terms of causing bodily injuries and death, destroying livelihoods and fracturing families. This paper examines how pipeline vandalisation affects human security in these ways. It identifies women and children as those who are hardest hit and questions why the poor are the most vulnerable in oil pipeline disasters in this country. It recommends the adoption of a comprehensive and integrated framework of disaster management that will ensure prompt response to key early warning signs, risk-reduction and appropriate mitigation and management strategies.

Disaster mitigation science for Earthquakes and Tsunamis -For resilience society against natural disasters-

NASA Astrophysics Data System (ADS)

Kaneda, Y.; Takahashi, N.; Hori, T.; Kawaguchi, K.; Isouchi, C.; Fujisawa, K.

2017-12-01

Destructive natural disasters such as earthquakes and tsunamis have occurred frequently in the world. For instance, 2004 Sumatra Earthquake in Indonesia, 2008 Wenchuan Earthquake in China, 2010 Chile Earthquake and 2011 Tohoku Earthquake in Japan etc., these earthquakes generated very severe damages. For the reduction and mitigation of damages by destructive natural disasters, early detection of natural disasters and speedy and proper evacuations are indispensable. And hardware and software developments/preparations for reduction and mitigation of natural disasters are quite important. In Japan, DONET as the real time monitoring system on the ocean floor is developed and deployed around the Nankai trough seismogenic zone southwestern Japan. So, the early detection of earthquakes and tsunamis around the Nankai trough seismogenic zone will be expected by DONET. The integration of the real time data and advanced simulation researches will lead to reduce damages, however, in the resilience society, the resilience methods will be required after disasters. Actually, methods on restorations and revivals are necessary after natural disasters. We would like to propose natural disaster mitigation science for early detections, evacuations and restorations against destructive natural disasters. This means the resilience society. In natural disaster mitigation science, there are lots of research fields such as natural science, engineering, medical treatment, social science and literature/art etc. Especially, natural science, engineering and medical treatment are fundamental research fields for natural disaster mitigation, but social sciences such as sociology, geography and psychology etc. are very important research fields for restorations after natural disasters. Finally, to realize and progress disaster mitigation science, human resource cultivation is indispensable. We already carried out disaster mitigation science under `new disaster mitigation research project on Mega thrust earthquakes around Nankai/Ryukyu subduction zone', and `SATREPS project of earthquake and tsunami disaster mitigation in the Marmara region and disaster education in Turkey'. Furthermore, we have to progress the natural disaster mitigation science against destructive natural disaster in the near future.

Planet Earth: Its Past, Our Present, A Future (?)

NASA Astrophysics Data System (ADS)

Kieffer, S. W.

2012-04-01

We who have lived through the second half of the 20th century into the 21st century have witnessed a profound transition in the biological and physical relationship between humans and the rest of the planet. In the middle of the last century, our planet still had undeveloped islands: there were frontiers that held new lands, mysteries, adventures, cultures, and resources. However, these islands have merged into a relatively seamless planet by a mobile and expanding population, science and technology, and global communication. We are subject to stealth as well as natural disasters. Natural disasters result from the ongoing geological and meteorological processes on our planet, increasingly exacerbated by human presence and behavior. Stealth disasters, on the other hand, are caused by humans, but involve the natural systems that support us. Examples of stealth disasters are climate change, loss of soils, acidification of the oceans, desertification, and loss of groundwater resources. Civilization is a complex system. It has emergent properties, and a tuning parameter--a parameter that is "tuned" until the unexpected happens. The tuning parameter for populations is the number of members relative to the capacities that support them. Because of our sheer numbers, we are driving the stealth disasters, and we will be affected more severely by natural disasters than we have been in the past on a less densely populated planet. To guide our thinking about geoethical issues, we propose a (hypothetical) world organization modeled after the Centers for Disease Control (CDC) in the U.S., and call it the Center for Disaster Control for Planet Earth (CDCPE). This center would have a scientific body to provide impartial facts and uncertainties, an engineering body to propose and implement technical solutions, a negotiating body to balance the realities of political, economic, religious and cultural values, and an enforcement body that is responsive to all of the inputs. How shall we start?

Performance of district disaster management teams after undergoing an operational level planners' training in Uganda.

PubMed

Orach, Christopher Garimol; Mayega, Roy William; Woboya, Vincent; William, Bazeyo

2013-06-01

Uganda is vulnerable to several natural, man-made and a hybrid of disasters including drought, famine, floods, warfare, and disease outbreaks. We assessed the district disaster team's performance, roles and experiences following the training. The disasters most commonly experienced by the district teams were epidemics of diseases in humans (7 of 12), animals (epizoonotics) (3 of 12) and crops (3 of 12); hailstorms and floods (3 of 12). The capabilities viewed most useful for management of disasters were provision of health care services (9/12) and response management (8 of 12). The capability domains most often consulted during the disasters were general response management (31%), health services (29%) and water and sanitation (17%). The skills areas perceived to be vital following the training were response to epidemics 10/12, disaster management planning 8/12, hazards and vulnerability analysis 7/12 and principles of disaster planning 7/12 respectively. Main challenges mentioned by district teams were inadequacy of finance and logistics, lack of commitment by key partners towards disaster preparedness and response. The most common disaster experienced disasters related to outbreaks of diseases in man, animals and crops. The most frequently applied capabilities were response management and provision of emergency health services. The activities most frequently implemented following disaster management teams training were conducting planning meetings, refinement of plans and dissemination of skills gained. The main challenges were related to limited budget allocations and legal frameworks for disaster management that should be addressed by both central and local governments.

The Shadow of the Past: studying the impact of typhoon Yolanda on human behavior

NASA Astrophysics Data System (ADS)

Kampenhuber, Lukas; Landmann, Andreas; Hayo, Bernd; Vollan, Björn

2017-04-01

The Philippines is one of the most exposed countries towards natural disasters in the world. Because of its location on the typhoon belt of the Pacific, the Philippines are exposed to an average of nineteen typhoons or tropical storms per year. One of the most devastating typhoons (Yolanda/Haiyan) occurred in 2013, with an approximate death toll of 6340 people. Following up on a study from 2012, we observe solidarity transfers in a lab-in-the-field experiment one year before and three years after typhoon Yolanda occurred. Based on this unique experimental panel-dataset we can define key elements that influence solidarity, such as fairness and effectiveness of disaster relief and potential corruption of governmental and non-governmental agencies. Furthermore we observe risk and time preferences across affected and non-affected regions and seek to get a better understanding of the effects of natural disasters on human behavior. Understanding the consequences of natural disasters on human behavior might be crucial to develop strategies to conquer the challenges that come with the increasing exposure to environmental risk. Furthermore, our study has important consequences for studies that seek to investigate the stability of economic preferences.

Communications infrastructure requirements for telemedicine/telehealth in the context of planning for and responding to natural disasters: Considering the need for shared regional networks

NASA Technical Reports Server (NTRS)

Scott, John Carver

1991-01-01

During the course of recent years the frequency and magnitude of major disasters - of natural, technological, or ecological origin - have made the world community dramatically aware of the immense losses of human life and economic resources that are caused regularly by such calamities. Particularly hard hit are developing countries, for whom the magnitude of disasters frequently outstrips the ability of the society to cope with them. In many cases this situation can be prevented, and the recent trend in disaster management has been to emphasize the importance of preparedness and mitigation as a means of prevention. In cases of disaster, a system is needed to respond to relief requirements, particularly the delivery of medical care. There is no generic telecommunications infrastructure appropriate for the variety of applications in medical care and disaster management. The need to integrate telemedicine/telehealth into shared regional disaster management telecommunications networks is discussed. Focus is on the development of infrastructure designed to serve the needs of disaster prone regions of the developing world.

Public Trauma after the Sewol Ferry Disaster: The Role of Social Media in Understanding the Public Mood.

PubMed

Woo, Hyekyung; Cho, Youngtae; Shim, Eunyoung; Lee, Kihwang; Song, Gilyoung

2015-09-03

The Sewol ferry disaster severely shocked Korean society. The objective of this study was to explore how the public mood in Korea changed following the Sewol disaster using Twitter data. Data were collected from daily Twitter posts from 1 January 2011 to 31 December 2013 and from 1 March 2014 to 30 June 2014 using natural language-processing and text-mining technologies. We investigated the emotional utterances in reaction to the disaster by analyzing the appearance of keywords, the human-made disaster-related keywords and suicide-related keywords. This disaster elicited immediate emotional reactions from the public, including anger directed at various social and political events occurring in the aftermath of the disaster. We also found that although the frequency of Twitter keywords fluctuated greatly during the month after the Sewol disaster, keywords associated with suicide were common in the general population. Policy makers should recognize that both those directly affected and the general public still suffers from the effects of this traumatic event and its aftermath. The mood changes experienced by the general population should be monitored after a disaster, and social media data can be useful for this purpose.

Public Trauma after the Sewol Ferry Disaster: The Role of Social Media in Understanding the Public Mood

PubMed Central

Woo, Hyekyung; Cho, Youngtae; Shim, Eunyoung; Lee, Kihwang; Song, Gilyoung

2015-01-01

The Sewol ferry disaster severely shocked Korean society. The objective of this study was to explore how the public mood in Korea changed following the Sewol disaster using Twitter data. Data were collected from daily Twitter posts from 1 January 2011 to 31 December 2013 and from 1 March 2014 to 30 June 2014 using natural language-processing and text-mining technologies. We investigated the emotional utterances in reaction to the disaster by analyzing the appearance of keywords, the human-made disaster-related keywords and suicide-related keywords. This disaster elicited immediate emotional reactions from the public, including anger directed at various social and political events occurring in the aftermath of the disaster. We also found that although the frequency of Twitter keywords fluctuated greatly during the month after the Sewol disaster, keywords associated with suicide were common in the general population. Policy makers should recognize that both those directly affected and the general public still suffers from the effects of this traumatic event and its aftermath. The mood changes experienced by the general population should be monitored after a disaster, and social media data can be useful for this purpose. PMID:26404349

Companion Animals, Natural Disasters and the Law: An Australian Perspective

PubMed Central

White, Steven

2012-01-01

Simple Summary One of the issues raised by recent natural disasters in Australia is the management of companion animal welfare in disaster planning, response and recovery. Official inquiries following these disasters uncovered a number of shortcomings in addressing the management of animal welfare issues. This article suggests that despite some reform following these events, disaster management still fails to take seriously the interests of companion animals. Abstract This article examines the regulation of companion animal welfare during disasters, with some context provided by two recent major disaster events in Australia. Important general lessons for improved disaster management were identified in subsequent inquiries. However, the interests of companion animals continue to be inadequately addressed. This is because key assumptions underpinning disaster planning for companion animals—the primacy of human interests over animal interests and that individuals will properly address companion animal needs during times of disaster—are open to question. In particular these assumptions fail to recognise the inherent value of companion animals, underestimate the strong bond shared by some owners and their animals and, at the same time, overestimate the capacity of some owners to adequately meet the needs of their animals. PMID:26487028

Infectious diseases following natural disasters: prevention and control measures.

PubMed

Kouadio, Isidore K; Aljunid, Syed; Kamigaki, Taro; Hammad, Karen; Oshitani, Hitoshi

2012-01-01

Natural disasters may lead to infectious disease outbreaks when they result in substantial population displacement and exacerbate synergic risk factors (change in the environment, in human conditions and in the vulnerability to existing pathogens) for disease transmission. We reviewed risk factors and potential infectious diseases resulting from prolonged secondary effects of major natural disasters that occurred from 2000 to 2011. Natural disasters including floods, tsunamis, earthquakes, tropical cyclones (e.g., hurricanes and typhoons) and tornadoes have been secondarily described with the following infectious diseases including diarrheal diseases, acute respiratory infections, malaria, leptospirosis, measles, dengue fever, viral hepatitis, typhoid fever, meningitis, as well as tetanus and cutaneous mucormycosis. Risk assessment is essential in post-disaster situations and the rapid implementation of control measures through re-establishment and improvement of primary healthcare delivery should be given high priority, especially in the absence of pre-disaster surveillance data.

Synthesis of Natural and Unnatural Cyclooligomeric Depsipeptides Enabled by Flow Chemistry.

PubMed

Lücke, Daniel; Dalton, Toryn; Ley, Steven V; Wilson, Zoe E

2016-03-14

Flow chemistry has been successfully integrated into the synthesis of a series of cyclooligomeric depsipeptides of three different ring sizes including the natural products beauvericin (1 a), bassianolide (2 b) and enniatin C (1 b). A reliable flow chemistry protocol was established for the coupling and macrocyclisation to form challenging N-methylated amides. This flexible approach has allowed the rapid synthesis of both natural and unnatural depsipeptides in high yields, enabling further exploration of their promising biological activity. © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Natural disasters: forecasting economic and life losses

USGS Publications Warehouse

Nishenko, Stuart P.; Barton, Christopher C.

1997-01-01

Events such as hurricanes, earthquakes, floods, tsunamis, volcanic eruptions, and tornadoes are natural disasters because they negatively impact society, and so they must be measured and understood in human-related terms. At the U.S. Geological Survey, we have developed a new method to examine fatality and dollar-loss data, and to make probabilistic estimates of the frequency and magnitude of future events. This information is vital to large sectors of society including disaster relief agencies and insurance companies.

No Pet or Their Person Left Behind: Increasing the Disaster Resilience of Vulnerable Groups through Animal Attachment, Activities and Networks.

PubMed

Thompson, Kirrilly; Every, Danielle; Rainbird, Sophia; Cornell, Victoria; Smith, Bradley; Trigg, Joshua

2014-05-07

Increased vulnerability to natural disasters has been associated with particular groups in the community. This includes those who are considered de facto vulnerable (children, older people, those with disabilities etc.) and those who own pets (not to mention pets themselves). The potential for reconfiguring pet ownership from a risk factor to a protective factor for natural disaster survival has been recently proposed. But how might this resilience-building proposition apply to vulnerable members of the community who own pets or other animals? This article addresses this important question by synthesizing information about what makes particular groups vulnerable, the challenges to increasing their resilience and how animals figure in their lives. Despite different vulnerabilities, animals were found to be important to the disaster resilience of seven vulnerable groups in Australia. Animal attachment and animal-related activities and networks are identified as underexplored devices for disseminating or 'piggybacking' disaster-related information and engaging vulnerable people in resilience building behaviors (in addition to including animals in disaster planning initiatives in general). Animals may provide the kind of innovative approach required to overcome the challenges in accessing and engaging vulnerable groups. As the survival of humans and animals are so often intertwined, the benefits of increasing the resilience of vulnerable communities through animal attachment is twofold: human and animal lives can be saved together.

Recommendations for Emergency Management Planning for School Facilities.

ERIC Educational Resources Information Center

Texas Education Agency, Austin.

Numerous events, such as hurricanes, floods, and tornadoes, constitute a natural disaster for public schools. Human-caused disasters include hazardous-material emergencies, civil riots, fires, and nuclear accidents. This document contains emergency-management planning guidelines, developed by the Texas Education Agency, to help local school…

Planetary Defense is More Than Science and Technology: Policy, People, and Disaster Management

NASA Astrophysics Data System (ADS)

Harrison, A. A.

2009-12-01

Physical scientists and engineers who work to identify and then deflect or destroy threatening Near Earth Objects deserve the support of colleagues who have a thorough understanding of human psychology, society and culture. Behavioral and social scientists can help build governmental and public support for vigorous and comprehensive programs of planetary defense as well as apply their work to minimize the human cost of NEO threats and impacts. Tasks include preparing the public for a succession of possible threats of differing levels; developing effective warning and evacuation strategies; and supporting residents of affected areas during the impact and recovery phases. Although much can be learned from the pre-existing disaster literature, it is important to remain mindful of differences between asteroid or comet impacts and other natural disasters such as hurricanes and earthquakes. After identifying widespread but erroneous stereotypes that exaggerate human weakness and interfere with effective disaster planning, we turn to models whereby international, national, and regional organizations help local communities and citizens develop the skills, attitudes and resources that they need to help protect their own welfare. These models view residents of disaster areas as part of the solution as well as part of the problem, acknowledge dangers and disruptions outside of the immediate impact area, and demand high sensitivity to political and cultural issues. We conclude with a brief discussion of strategies for preserving the human legacy under worst-case scenarios including the construction and administration of survival communities and sending time capsules into space. Anthropology, political science, psychology and sociology are already contributing to astrobiology and SETI, and it is time for researchers and practitioners in these areas to become conspicuous partners in the pursuit of planetary defense.

Measuring and Modeling Behavioral Decision Dynamics in Collective Evacuation

PubMed Central

Carlson, Jean M.; Alderson, David L.; Stromberg, Sean P.; Bassett, Danielle S.; Craparo, Emily M.; Guiterrez-Villarreal, Francisco; Otani, Thomas

2014-01-01

Identifying and quantifying factors influencing human decision making remains an outstanding challenge, impacting the performance and predictability of social and technological systems. In many cases, system failures are traced to human factors including congestion, overload, miscommunication, and delays. Here we report results of a behavioral network science experiment, targeting decision making in a natural disaster. In a controlled laboratory setting, our results quantify several key factors influencing individual evacuation decision making in a controlled laboratory setting. The experiment includes tensions between broadcast and peer-to-peer information, and contrasts the effects of temporal urgency associated with the imminence of the disaster and the effects of limited shelter capacity for evacuees. Based on empirical measurements of the cumulative rate of evacuations as a function of the instantaneous disaster likelihood, we develop a quantitative model for decision making that captures remarkably well the main features of observed collective behavior across many different scenarios. Moreover, this model captures the sensitivity of individual- and population-level decision behaviors to external pressures, and systematic deviations from the model provide meaningful estimates of variability in the collective response. Identification of robust methods for quantifying human decisions in the face of risk has implications for policy in disasters and other threat scenarios, specifically the development and testing of robust strategies for training and control of evacuations that account for human behavior and network topologies. PMID:24520331

The Effects of Disaster on Women's Reproductive Health in Developing Countries

PubMed Central

Swatzyna, Ronald J.; Pillai, Vijayan K.

2013-01-01

The objective of this study is to empirically test the effects of disasters which include natural as well as human made disasters such as armed conflict on women's reproductive health in developing countries. Data from 128 developing countries are used. It was found that average number of deaths from natural disasters and armed conflict in the East Asia and Pacific region was not significantly different from the rest of the developing world. The data are examined using structural equation analysis. This study finds that ‘armed conflict’ in developing countries presents significant reproductive health risks. The implications are discussed. PMID:23777727

Leveraging Social Media Data to Understand Disaster Resilience: A Case Study of Hurricane Isaac

NASA Astrophysics Data System (ADS)

Zou, L.; Lam, N.; Cai, H.

2017-12-01

Coastal communities are facing multiple threats from natural hazards, such as hurricanes, flooding, and storm surge, and show uneven response and recovery behaviors. To build a sustainable coast, it is critical to understand how coastal hazards affect humans and how to enhance disaster resilience. However, understanding community resilience remains challenging, due to the lack of real-time data describing community's response and recovery behaviors during disasters. Public discussion through social media platforms provides an opportunity to understand these behaviors by categorizing real-time social media data into three main phases of emergency management - preparedness, response, and recovery. This study analyzes the spatial-temporal patterns of Twitter use and content during Hurricane Isaac, which struck coastal Louisiana on August 29, 2012. The study area includes counties affected by Hurricane Isaac in Louisiana and Mississippi. The objectives are three-fold. First, we will compute a set of Twitter indices to quantify the Twitter activities during Hurricane Issac and the results will be compared with those of Hurricane Sandy to gain a better understanding of human response in extreme events. Second, county-level disaster resilience in the affected region will be computed and evaluated using the Resilience Inference Measurement (RIM) model. Third, we will examine the relationship between the geographical and social disparities in Twitter use and the disparities in disaster resilience and evaluate the role of Twitter use in disaster resilience. Knowledge gained from this study could provide valuable insights into strategies for utilizing social media data to increase resilience to disasters.

Lightning fatalities in the Transkei sub-region of South Africa.

PubMed

Meel, B L

2007-04-01

Lightning is a particularly unsettling product of bad weather. It kills more people than other natural disasters such as floods, hurricanes, and tornadoes, but, because lightning usually kills people one at a time, it tends to be an underrated hazard. High risk groups are uneducated, unsheltered and rural people. This study was carried out to determine the incidence of lightning fatalities in the Transkei sub-region. It is a review of records between 1993 and 2004 from the medico-legal autopsies at Umtata General Hospital (UGH). During the study period there were 10,860 autopsies performed on those who died of trauma and other unnatural circumstances which included 151 (1.4%) lightning fatalities. This represents 0.31 deaths per million per year. The highest (0.5/million) was in 1999, and the lowest (0.13/million) in 1997. The age of the victims ranged from 1 to 82 years, with a mean of 22 years. Males and females were almost equally represented (50%). The highest number of deaths (26.5%) was in the age group of 11 to 20 years, and the lowest number (2.7%) in the age group of 70+ years. There is a high incidence of lightning fatalities in the Transkei sub-region of South Africa. People need to be educated to disregard the myths of lightning strike.

Epitome of China's unnatural deaths: a historically retrospective study of forensic autopsy cases in Shanghai Public Security Bureau from 1990 to 1999.

PubMed

He, Meng; Li, Wen-Can; Sun, Da-Ming; Ma, Kai-Jun; Zhao, Zi-Qin; Li, Bei-Xu; Li, Ling

2014-09-01

The unnatural death investigation in China seems vague to the world. Shanghai is one of the largest city located in Yangtze River Delta in the East China. This study is committed to lift the veil of unnatural death investigation and describe the epitome of China's unnatural deaths. Based on the 7302 forensic report archives from 1990 to 1999 in Shanghai Public Security Bureau, statistics were carried out in 5 areas according to the manner of death. In 3502 accidental deaths, there was a rapid increase during the 1990s, and 71.6% were involved in traffic accidents whose major cause of death was head and neck injuries. The first 3 causes of death in nontraffic accidents (994) were head and neck injuries (42.8%), poisoning (11.8%), and drowning (9.0%). In 2456 homicides, sharp force injury (36.7%), blunt force injury (35.8%), and manual strangulation (12.9%) were the first 3 causes of death. In 563 suicides, drug/chemical intoxication (40.1%), hanging (23.4%), and injuries because of fall from height (11.4%) were the 3 leading causes of death, especially pesticides ingestion. The causes of natural deaths were diseases mainly in circulatory system (23.1%), central nervous system (12.8%), and respiratory system (6.4%). However, the cause of death remained undetermined in 500 victims. Childhood fatalities were different. The victims of accidents and homicides were nearly equal, and the main cause of homicide was manual strangulation. Besides, 1997 was the landmark year when drug abuse began to emerge in Shanghai.

Human Costs of Flooding the 1979 ’Easter’ Flood at Jackson, Mississippi.

DTIC Science & Technology

1984-04-01

in psschiatr-: the psichological aftermath of disaster. JOURNAL OF CLINICAL PSYCHIATRY, 4(7):238-244, 1980. Previous research on phisical and...mone for psichological damages i, a court action suit, it was r,ecessar5 to learn what the flood Meant to survivors and how it affected the course of...Laurence C. F’s-chological aspects of disaster. AMERICAN JOURNAL OF PUBLIC HEALTH, 54(4):638-643, 1964. The psichological aspects of disaster are presented

Designing to Control Flight Crew Errors

NASA Technical Reports Server (NTRS)

Schutte, Paul C.; Willshire, Kelli F.

1997-01-01

It is widely accepted that human error is a major contributing factor in aircraft accidents. There has been a significant amount of research in why these errors occurred, and many reports state that the design of flight deck can actually dispose humans to err. This research has led to the call for changes in design according to human factors and human-centered principles. The National Aeronautics and Space Administration's (NASA) Langley Research Center has initiated an effort to design a human-centered flight deck from a clean slate (i.e., without constraints of existing designs.) The effort will be based on recent research in human-centered design philosophy and mission management categories. This design will match the human's model of the mission and function of the aircraft to reduce unnatural or non-intuitive interfaces. The product of this effort will be a flight deck design description, including training and procedures, and a cross reference or paper trail back to design hypotheses, and an evaluation of the design. The present paper will discuss the philosophy, process, and status of this design effort.

A synthesized biophysical and social vulnerability assessment for Taiwan

NASA Astrophysics Data System (ADS)

Lee, Yung-Jaan

2017-11-01

Taiwan, located in the Western Pacific, is a country that is one of the most vulnerable to disasters that are associated with the changing climate; it is located within the Ring of Fire, which is the most geologically active region in the world. The environmental and geological conditions in Taiwan are sensitive and vulnerable to such disasters. Owing to increasing urbanization in Taiwan, floods and climate-related disasters have taken an increasing toll on human lives. As global warming accelerates the rising of sea levels and increasing of the frequency of extreme weather events, disasters will continue to affect socioeconomic development and human conditions. Under such circumstances, researchers and policymakers alike must recognize the importance of providing useful knowledge concerning vulnerability, disaster recovery and resilience. Strategies for reducing vulnerability and climate-related disaster risks and for increasing resilience involve preparedness, mitigation and adaptation. In the last two decades, extreme climate events have caused severe flash floods, debris flows, landslides, and other disasters and have had negative effects of many sectors, including agriculture, infrastructure and health. Since climate change is expected to have a continued impact on socio-economic development, this work develops a vulnerability assessment framework that integrates both biophysical and social vulnerability and supports synthesized vulnerability analyses to identify vulnerable areas in Taiwan. Owing to its geographical, geological and climatic features, Taiwan is susceptible to earthquakes, typhoons, droughts and various induced disasters. Therefore, Taiwan has the urgent task of establishing a framework for assessing vulnerability as a planning and policy tool that can be used to identify not only the regions that require special attention but also hotspots in which efforts should be made to reduce vulnerability and the risk of climate-related disaster. To analyze the biophysical vulnerability of Taiwan, hazards on eight maps from Taiwan’s National Science and Technology Center for Disaster Reduction (NCDR) are analyzed. Statistical data from the NCDR on social vulnerability are also adopted. Finally, a GIS overlaying method was used to perform the synthesized vulnerability analysis of biophysical and social vulnerability for municipalities and counties in Taiwan.

Coherent Multimodal Sensory Information Allows Switching between Gravitoinertial Contexts

PubMed Central

Barbiero, Marie; Rousseau, Célia; Papaxanthis, Charalambos; White, Olivier

2017-01-01

Whether the central nervous system is capable to switch between contexts critically depends on experimental details. Motor control studies regularly adopt robotic devices to perturb the dynamics of a certain task. Other approaches investigate motor control by altering the gravitoinertial context itself as in parabolic flights and human centrifuges. In contrast to conventional robotic experiments, where only the hand is perturbed, these gravitoinertial or immersive settings coherently plunge participants into new environments. However, radically different they are, perfect adaptation of motor responses are commonly reported. In object manipulation tasks, this translates into a good matching of the grasping force or grip force to the destabilizing load force. One possible bias in these protocols is the predictability of the forthcoming dynamics. Here we test whether the successful switching and adaptation processes observed in immersive environments are a consequence of the fact that participants can predict the perturbation schedule. We used a short arm human centrifuge to decouple the effects of space and time on the dynamics of an object manipulation task by adding an unnatural explicit position-dependent force. We created different dynamical contexts by asking 20 participants to move the object at three different paces. These contextual sessions were interleaved such that we could simulate concurrent learning. We assessed adaptation by measuring how grip force was adjusted to this unnatural load force. We found that the motor system can switch between new unusual dynamical contexts, as reported by surprisingly well-adjusted grip forces, and that this capacity is not a mere consequence of the ability to predict the time course of the upcoming dynamics. We posit that a coherent flow of multimodal sensory information born in a homogeneous milieu allows switching between dynamical contexts. PMID:28553233

Enhanced learning of natural visual sequences in newborn chicks.

PubMed

Wood, Justin N; Prasad, Aditya; Goldman, Jason G; Wood, Samantha M W

2016-07-01

To what extent are newborn brains designed to operate over natural visual input? To address this question, we used a high-throughput controlled-rearing method to examine whether newborn chicks (Gallus gallus) show enhanced learning of natural visual sequences at the onset of vision. We took the same set of images and grouped them into either natural sequences (i.e., sequences showing different viewpoints of the same real-world object) or unnatural sequences (i.e., sequences showing different images of different real-world objects). When raised in virtual worlds containing natural sequences, newborn chicks developed the ability to recognize familiar images of objects. Conversely, when raised in virtual worlds containing unnatural sequences, newborn chicks' object recognition abilities were severely impaired. In fact, the majority of the chicks raised with the unnatural sequences failed to recognize familiar images of objects despite acquiring over 100 h of visual experience with those images. Thus, newborn chicks show enhanced learning of natural visual sequences at the onset of vision. These results indicate that newborn brains are designed to operate over natural visual input.

A Conceptual Framework to Address Stress-Associated Human Health Effects of Ecosystem Services Degraded by Disasters

EPA Science Inventory

Chronic stress leads to a variety of mental and physiological disorders, and stress effects are the primary concern after traumatic injury and exposure to infectious diseases or toxic agents from disaster events. We developed a conceptual model to address the question of whether...

75 FR 9605 - Notice of Meeting; National Commission on Children and Disasters

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Notice of Meeting; National Commission on Children and Disasters AGENCY: Administration for Children and Families, Department... for Children and Families, 901 D Street SW., Washington, DC 20024. To attend either in person or via...

75 FR 21339 - Notice of Meeting; National Commission on Children and Disasters

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-23

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Notice of Meeting; National Commission on Children and Disasters AGENCY: Administration for Children and Families, Department... for Children and Families, 901 D Street, SW., Washington, DC 20024. To attend either in person or via...

75 FR 64311 - Notice of Meeting; National Commission on Children and Disasters

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-19

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Notice of Meeting; National Commission on Children and Disasters AGENCY: Administration for Children and Families, Department... for Children and Families, 901 D Street, SW., Washington, DC 20024. To attend either in person or via...

75 FR 45132 - Notice of Meeting; National Commission on Children and Disasters

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Notice of Meeting; National Commission on Children and Disasters AGENCY: Administration for Children and Families, Department... for Children and Families, 901 D Street SW., Washington, DC 20024. To attend either in person or via...

76 FR 9352 - Notice of Meeting; National Commission on Children and Disasters

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-17

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Notice of Meeting; National Commission on Children and Disasters AGENCY: Administration for Children and Families, Department... for Children and Families, 901 D Street, SW., Washington, DC 20024. To attend either in person or via...

75 FR 876 - Notice of Meeting; National Commission on Children and Disasters

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Notice of Meeting; National Commission on Children and Disasters AGENCY: Administration for Children and Families, Department... Children and Families, 901 D Street, SW., Washington, DC 20024. To attend either in person or via...

Teaching Biology Field Courses in the Wake of Environmental Disasters.

ERIC Educational Resources Information Center

Baca, Bart J.

1982-01-01

A biology field course organized to study the effects of the June 1979 Mexican oil spill on the marine biology of the shores of south Texas and Mexico is described, demonstrating how to effectively couple a biology classroom course with a natural or human caused environmental disaster. (Author/DC)

The Challenge of Survival. Bulletin 1976, No. 16.

ERIC Educational Resources Information Center

Alabama State Dept. of Education, Montgomery. Div. of Instructional Services.

This booklet is intended to accompany lessons dealing with threats to human survival. It addresses both natural and man-made disasters. Chapters present photos and diagrams along with descriptions of specific threats and suggested approaches to dealing with them. Chapters include: (1) Disasters, (2) Survival in the Nuclear Age, (3) Civil…

Hazard Assessment of Landslide Disaster in Fujian Province Based on Fuzzy Mathematics

NASA Astrophysics Data System (ADS)

Wang, J. M.; Gong, A. D.; Chen, Y. L.; Li, J.; Zeng, T. T.

2018-04-01

Landslide disasters are the most frequent geological disasters in Fujian Province. They are also the type of geological disasters that cause the most serious economic and population losses each year. This study uses the fuzzy mathematics method to carry on the hazard assessment of landslide disaster in Fujian Province, in order to explore the mechanism of the landslide disaster, and provides the reference for the construction land expansion in Fujian Province. The calculation results show that landslide disasters in Fujian Province have a high correlation with external forces, that is, long-term precipitation and short-term strong precipitation are likely to trigger landslide disasters. Among the internal stress factors, the correlation between the occurrence of landslides and slopes is the highest, and the probability of landslides occurs in areas with steep slopes. The evaluation results show that the areas with high landslide hazards are mainly distributed in the central region of Fujian Province. From the remote sensing images, it can be seen that most of the dangerous areas are in rapidly developing cities, and their vegetation coverage is relatively low, and the environment is greatly affected by humans.

Disaster psychiatry and traumatic stress studies in Norway. History, current status and future.

PubMed

Malt, U F; Weisaeth, L

1989-01-01

The breakthrough of Norwegian disaster psychiatry and traumatic stress studies came when the "Board of Norwegian Doctors of 1957" carried out exceptionally thorough and comprehensive studies of former concentration camp prisoners. These studies convincingly demonstrated that chronic mental illnesses could develop in persons who had a harmonious childhood but who had been subject to extreme physical and psychological stress. During the seventies Norway became the first country in the world to have a University chair of disaster psychiatry. The scope of the field was broadened by the initiation of several studies on traumatic neurosis, industrial disaster and injuries. The support from the Joint Norwegian Armed Forces Medical Services, the University of Oslo, the Norwegian Research Council for Science and the Humanities, and later the Royal Norwegian Council for Scientific and Technical Research, was crucial for this development. Currently stress and disaster psychiatry has become an integrated part of the care of victims who have suffered individual or collective disaster. Disaster psychiatry is taught in medical schools and is part of the obligatory training for residents in psychiatry.

Epidemic activity after natural disasters without high mortality in developing settings

PubMed Central

Loayza-Alarico, Manuel J; Lescano, Andres G; Suarez-Ognio, Luis A; Ramirez-Prada, Gladys M; Blazes, David L

2013-01-01

Natural disasters with minimal human mortality rarely capture headlines but occur frequently and result in significant morbidity and economic loss. We compared the epidemic activity observed after a flood, an earthquake, and volcanic activity in Peru. Following post-disaster guidelines, healthcare facilities and evacuation centers surveyed 10–12 significant health conditions for ~45 days and compared disease frequency with Poisson regression. The disasters affected 20,709 individuals and 15% were placed in evacuation centers. Seven deaths and 6,056 health conditions were reported (mean: 0.29 per person). Health facilities reported fewer events than evacuation centers (0.06–0.24 vs. 0.65–2.02, P < 0.001) and disease notification increased 1.6 times after the disasters (95% CI: 1.5–1.6). Acute respiratory infections were the most frequent event (41–57%) and psychological distress was second/third (7.6% to 14.3%). Morbidity increased after disasters without substantial casualties, particularly at evacuation centers, with frequent respiratory infections and psychological distress. Post-disaster surveillance is valuable even after low-mortality events. PMID:28228992

Post-traumatic stress disorder following disasters: a systematic review

PubMed Central

Neria, Y.; Nandi, A.; Galea, S.

2016-01-01

Background Disasters are traumatic events that may result in a wide range of mental and physical health consequences. Post-traumatic stress disorder (PTSD) is probably the most commonly studied post-disaster psychiatric disorder. This review aimed to systematically assess the evidence about PTSD following exposure to disasters. Method A systematic search was performed. Eligible studies for this review included reports based on the DSM criteria of PTSD symptoms. The time-frame for inclusion of reports in this review is from 1980 (when PTSD was first introduced in DSM-III) and February 2007 when the literature search for this examination was terminated. Results We identified 284 reports of PTSD following disasters published in peer-reviewed journals since 1980. We categorized them according to the following classification: (1) human-made disasters (n=90), (2) technological disasters (n=65), and (3) natural disasters (n=116). Since some studies reported on findings from mixed samples (e.g. survivors of flooding and chemical contamination) we grouped these studies together (n=13). Conclusions The body of research conducted after disasters in the past three decades suggests that the burden of PTSD among persons exposed to disasters is substantial. Post-disaster PTSD is associated with a range of correlates including sociodemographic and background factors, event exposure characteristics, social support factors and personality traits. Relatively few studies have employed longitudinal assessments enabling documentation of the course of PTSD. Methodological limitations and future directions for research in this field are discussed. PMID:17803838

The use of psychological first aid (PFA) training among nurses to enhance population resiliency.

PubMed

Everly, George S; Barnett, Daniel J; Sperry, Nancy L; Links, Jonathan M

2010-01-01

Disaster mental health research has found that psychological casualties from a given disaster can be expected to far outnumber physical casualties. Amidst a shortage of mental health professionals and against the backdrop of natural disasters, continued terrorism, and pandemic influenza, there is a striking need to expand and operationalize available human resources to enhance the psychological resiliency of those affected. Through the utilization of psychological first aid (PFA) as an early crisis intervention tool, and by virtue of their occupation and experience, nurses are particularly well-suited to assume a leadership role in expanding the disaster mental health presence beyond the existing cadre of mental health clinicians. Here, we characterize the importance of integrating PFA in the context of other nursing functions, to augment mental health surge capacity in disaster settings.

How pediatricians can respond to the psychosocial implications of disasters. American Academy of Pediatrics. Committee on Psychosocial Aspects of Child and Family Health, 1998-1999.

PubMed

Wolraich, M L; Aceves, J; Feldman, H M; Hagan, J F; Howard, B J; Navarro, A; Richtsmeier, A J; Tolmas, H C

1999-02-01

Natural and human-caused disasters, violence with weapons, and terrorist acts have touched directly the lives of thousands of families with children in the United States.1 Media coverage of disasters has brought images of floods, hurricanes, and airplane crashes into the living rooms of most American families, with limited censorship for vulnerable young children. Therefore, children may be exposed to disastrous events in ways that previous generations never or rarely experienced. Pediatricians should serve as important resources to the community in preparing for disasters, as well as acting in its behalf during and after such events.

Development of a Disaster Information Visualization Dashboard: A Case Study of Three Typhoons in Taiwan in 2016

NASA Astrophysics Data System (ADS)

Su, Wen-Ray; Tsai, Yuan-Fan; Huang, Kuei-Chin; Hsieh, Ching-En

2017-04-01

To facilitate disaster response and enhance the effectiveness of disaster prevention and relief, people and emergency response personnel should be able to rapidly acquire and understand information when disasters occur. However, in existing disaster platforms information is typically presented in text tables, static charts, and maps with points. These formats do not make it easy for users to understand the overall situation. Therefore, this study converts data into human-readable charts by using data visualization techniques, and builds a disaster information dashboard that is concise, attractive and flexible. This information dashboard integrates temporally and spatially correlated data, disaster statistics according to category and county, lists of disasters, and any other relevant information. The graphs are animated and interactive. The dashboard allows users to filter the data according to their needs and thus to assimilate the information more rapidly. In this study, we applied the information dashboard to the analysis of landslides during three typhoon events in 2016: Typhoon Nepartak, Typhoon Meranti and Typhoon Megi. According to the statistical results in the dashboard, the order of frequency of the disaster categories in all three events combined was rock fall, roadbed loss, slope slump, road blockage and debris flow. Disasters occurred mainly in the areas that received the most rainfall. Typhoons Nepartak and Meranti mainly affected Taitung, and Typhoon Megi mainly affected Kaohsiung. The towns Xiulin, Fengbin, Fenglin and Guangfu in Hualian County were all issued with debris flow warnings in all three typhoon events. The disaster information dashboard developed in this study allows the user to rapidly assess the overall disaster situation. It clearly and concisely reveals interactions between time, space and disaster type, and also provides comprehensive details about the disaster. The dashboard provides a foundation for future disaster visualization, since it can combine and present real-time information of various types; as such it will strengthen decision making in disaster prevention management.

Stereoselective synthesis of functionalized cyclic amino acid derivatives via a [2,3]-Stevens rearrangement and ring-closing metathesis.

PubMed

Nash, Aaron; Soheili, Arash; Tambar, Uttam K

2013-09-20

Unnatural cyclic amino acids are valuable tools in biomedical research and drug discovery. A two-step stereoselective strategy for converting simple glycine-derived aminoesters into unnatural cyclic amino acid derivatives has been developed. The process includes a palladium-catalyzed tandem allylic amination/[2,3]-Stevens rearrangement followed by a ruthenium-catalyzed ring-closing metathesis. The [2,3]-rearrangement proceeds with high diastereoselectivity through an exo transition state. Oppolzer's chiral auxiliary was utilized to access an enantiopure cyclic amino acid by this approach, which will enable future biological applications.

Selective posttranslational modification of phage-displayed polypeptides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsao, Meng-Lin; Tian, Feng; Schultz, Peter

The invention relates to posttranslational modification of phage-displayed polypeptides. These displayed polypeptides comprise at least one unnatural amino acid, e.g., an aryl-azide amino acid such as p-azido-L-phenylalanine, or an alkynyl-amino acid such as para-propargyloxyphenylalanine, which are incorporated into the phage-displayed fusion polypeptide at a selected position by using an in vivo orthogonal translation system comprising a suitable orthogonal aminoacyl-tRNA synthetase and a suitable orthogonal tRNA species. These unnatural amino acids advantageously provide targets for posttranslational modifications such as azide-alkyne [3+2] cycloaddition reactions and Staudinger modifications.

Selective posttranslational modification of phage-displayed polypeptides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsao, Meng-Lin; Tian, Feng; Schultz, Peter

The invention relates to posttranslational modification of phage-displayed polypeptides. These displayed polypeptides comprise at least one unnatural amino acid, e.g., an aryl-azide amino acid such as p-azido-L-phenylalanine, or an alkynyl-amino acid such as para-propargyloxyphenylalanine, which are incorporated into the phage-displayed fusion polypeptide at a selected position by using an in vivo orthogonal translation system comprising a suitable orthogonal aminoacyl-tRNA synthetase and a suitable orthogonal tRNA species. These unnatural amino acids advantageously provide targets for posttranslational modifications such as azide-alkyne [3+2]cycloaddition reactions and Staudinger modifications.

Scalable Algorithms for Global Scale Remote Sensing Applications

NASA Astrophysics Data System (ADS)

Vatsavai, R. R.; Bhaduri, B. L.; Singh, N.

2015-12-01

Recent decade has witnessed major changes on the Earth, for example, deforestation, varying cropping and human settlement patterns, and crippling damages due to disasters. Accurate damage assessment caused by major natural and anthropogenic disasters is becoming critical due to increases in human and economic loss. This increase in loss of life and severe damages can be attributed to the growing population, as well as human migration to the disaster prone regions of the world. Rapid assessment of these changes and dissemination of accurate information is critical for creating an effective emergency response. Change detection using high-resolution satellite images is a primary tool in assessing damages, monitoring biomass and critical infrastructures, and identifying new settlements. Existing change detection methods suffer from registration errors and often based on pixel (location) wise comparison of spectral observations from single sensor. In this paper we present a novel probabilistic change detection framework based on patch comparison and a GPU implementation that supports near real-time rapid damage exploration capability.

Ketone isosteres of 2-N-acetamidosugars as substrates for metabolic cell surface engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hang, Howard C.; Bertozzi, Carolyn R.

2000-08-22

Novel chemical reactivity can be engendered on cell surfaces by the metabolic incorporation of unnatural sugars into cell surface glycoconjuagtes. 2-N-Acetamido sugars such as GalNAc and GlcNAc are abundant components of cell surface glycoconjugates, and hence attractive targets for metabolic cell surface engineering. Here we report (1) the synthesis of isosteric analogs bearing a ketone group in place of the N-acetamido group, and (2) evaluation of their metabolic incorporation into mammalian cell surface glycans. A ketone isostere of GalNAc was metabolized by CHO cells through the salvage pathway and delivered to O-linked glycoproteins on the cell surface. Its residence atmore » the core position of O-linked glycans is suggested by studies with a-benzyl GalNAc, an inhibitor of O-linked oligosaccharide extension. A mutant CHO cell line lacking endogenous UDP-GalNAc demonstrated enhanced metabolism of the GalNAc analog, suggesting that competition with native intermediates might limits enzymatic transformation in mammalian cells. A ketone isostere of GlcNAc could not be detected on CHO or human cell surfaces after incubation. Thus, the enzymes in the GlcNAc salvage pathway might be less permissive of unnatural substrates than those comprising the GalNAc salvage pathway. Alternatively, high levels of endogenous GlcNAc derivatives might compete with the ketone isostere and prevent its incorporation into oligosaccharides.« less

Community Disasters, Psychological Trauma, and Crisis Intervention.

PubMed

Boscarino, Joseph A

The current issue of International Journal of Emergency Mental Health and Human Resilience is focused on community disasters, the impact of trauma exposure, and crisis intervention. The articles incorporated include studies ranging from the World Trade Center disaster to Hurricane Sandy. These studies are related to public attitudes and beliefs about disease outbreaks, the impact of volunteerism following the World Trade Center attacks, alcohol misuse among police officers after Hurricane Katrina, posttraumatic stress disorder after Hurricane Sandy among those exposed to the Trade Center disaster, compassion fatigue and burnout among trauma workers, crisis interventions in Eastern Europe, and police officers' use of stress intervention services. While this scope is broad, it reflects the knowledge that has emerged since the Buffalo Creek and Chernobyl catastrophes, to the more recent Hurricane Katrina and Sandy disasters. Given the current threat environment, psychologists, social workers, and other providers need to be aware of these developments and be prepared to mitigate the impact of psychological trauma following community disasters, whether natural or man-made.

Business closure and relocation: a comparative analysis of the Loma Prieta earthquake and Hurricane Andrew.

PubMed

Wasileski, Gabriela; Rodríguez, Havidán; Diaz, Walter

2011-01-01

The occurrence of a number of large-scale disasters or catastrophes in recent years, including the Indian Ocean tsunami (2004), the Kashmir earthquake (2005), Hurricane Katrina (2005) and Hurricane Ike (2008), have raised our awareness regarding the devastating effects of disasters on human populations and the importance of developing mitigation and preparedness strategies to limit the consequences of such events. However, there is still a dearth of social science research focusing on the socio-economic impact of disasters on businesses in the United States. This paper contributes to this research literature by focusing on the impact of disasters on business closure and relocation through the use of multivariate logistic regression models, specifically focusing on the Loma Prieta earthquake (1989) and Hurricane Andrew (1992). Using a multivariate model, we examine how physical damage to the infrastructure, lifeline disruption and business characteristics, among others, impact business closure and relocation following major disasters. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.

Analysing news media coverage of the 2015 Nepal earthquake using a community capitals lens: implications for disaster resilience.

PubMed

Dhakal, Subas P

2018-04-01

South Asia is one of the regions of the world most vulnerable to natural disasters. Although news media analyses of disasters have been conducted frequently in various settings globally, there is little research on populous South Asia. This paper begins to fill this gap by evaluating local and foreign news media coverage of the earthquake in Nepal on 25 April 2015. It broadens the examination of news media coverage of disaster response beyond traditional framing theory, utilising community capitals (built, cultural, financial, human, natural, political, and social) lens to perform a thematic content analysis of 405 news items. Overall, financial and natural capital received the most and the least emphasis respectively. Statistically significant differences between local and foreign news media were detected vis-à-vis built, financial, and political capital. The paper concludes with a discussion of the social utility of news media analysis using the community capitals framework to inform disaster resilience. © 2018 The Author(s). Disasters © Overseas Development Institute, 2018.

Integrating Urban Infrastructure and Health System Impact Modeling for Disasters and Mass-Casualty Events

NASA Astrophysics Data System (ADS)

Balbus, J. M.; Kirsch, T.; Mitrani-Reiser, J.

2017-12-01

Over recent decades, natural disasters and mass-casualty events in United States have repeatedly revealed the serious consequences of health care facility vulnerability and the subsequent ability to deliver care for the affected people. Advances in predictive modeling and vulnerability assessment for health care facility failure, integrated infrastructure, and extreme weather events have now enabled a more rigorous scientific approach to evaluating health care system vulnerability and assessing impacts of natural and human disasters as well as the value of specific interventions. Concurrent advances in computing capacity also allow, for the first time, full integration of these multiple individual models, along with the modeling of population behaviors and mass casualty responses during a disaster. A team of federal and academic investigators led by the National Center for Disaster Medicine and Public Health (NCDMPH) is develoing a platform for integrating extreme event forecasts, health risk/impact assessment and population simulations, critical infrastructure (electrical, water, transportation, communication) impact and response models, health care facility-specific vulnerability and failure assessments, and health system/patient flow responses. The integration of these models is intended to develop much greater understanding of critical tipping points in the vulnerability of health systems during natural and human disasters and build an evidence base for specific interventions. Development of such a modeling platform will greatly facilitate the assessment of potential concurrent or sequential catastrophic events, such as a terrorism act following a severe heat wave or hurricane. This presentation will highlight the development of this modeling platform as well as applications not just for the US health system, but also for international science-based disaster risk reduction efforts, such as the Sendai Framework and the WHO SMART hospital project.

Combining Human Computing and Machine Learning to Make Sense of Big (Aerial) Data for Disaster Response.

PubMed

Ofli, Ferda; Meier, Patrick; Imran, Muhammad; Castillo, Carlos; Tuia, Devis; Rey, Nicolas; Briant, Julien; Millet, Pauline; Reinhard, Friedrich; Parkan, Matthew; Joost, Stéphane

2016-03-01

Aerial imagery captured via unmanned aerial vehicles (UAVs) is playing an increasingly important role in disaster response. Unlike satellite imagery, aerial imagery can be captured and processed within hours rather than days. In addition, the spatial resolution of aerial imagery is an order of magnitude higher than the imagery produced by the most sophisticated commercial satellites today. Both the United States Federal Emergency Management Agency (FEMA) and the European Commission's Joint Research Center (JRC) have noted that aerial imagery will inevitably present a big data challenge. The purpose of this article is to get ahead of this future challenge by proposing a hybrid crowdsourcing and real-time machine learning solution to rapidly process large volumes of aerial data for disaster response in a time-sensitive manner. Crowdsourcing can be used to annotate features of interest in aerial images (such as damaged shelters and roads blocked by debris). These human-annotated features can then be used to train a supervised machine learning system to learn to recognize such features in new unseen images. In this article, we describe how this hybrid solution for image analysis can be implemented as a module (i.e., Aerial Clicker) to extend an existing platform called Artificial Intelligence for Disaster Response (AIDR), which has already been deployed to classify microblog messages during disasters using its Text Clicker module and in response to Cyclone Pam, a category 5 cyclone that devastated Vanuatu in March 2015. The hybrid solution we present can be applied to both aerial and satellite imagery and has applications beyond disaster response such as wildlife protection, human rights, and archeological exploration. As a proof of concept, we recently piloted this solution using very high-resolution aerial photographs of a wildlife reserve in Namibia to support rangers with their wildlife conservation efforts (SAVMAP project, http://lasig.epfl.ch/savmap ). The results suggest that the platform we have developed to combine crowdsourcing and machine learning to make sense of large volumes of aerial images can be used for disaster response.

Getting HBCUs in the Disaster-Response Loop

ERIC Educational Resources Information Center

Colston, Ladd G.

2005-01-01

Natural and man-made disasters represent an ominous threat to the research, instructional and public service missions of colleges and universities. From the bombings in Oklahoma City to the terrorist attacks of Sept. 11 to last year's Hurricane Frances, the potential damage to campus buildings, human life and irreplaceable archival resources is a…

Psychosocial Issues for Children and Adolescents in Disasters. Second Edition.

ERIC Educational Resources Information Center

Speier, Anthony H.

Major natural and human-caused disasters deeply affect children, and they have a special vulnerability to such events. The importance of providing crisis counseling recovery assistance within the context of their special world cannot be over emphasized. The information in this manual provides both theory and guidance to individuals concerned with…

78 FR 13844 - Change in Submission Requirements for State Mitigation Plans

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-01

... protecting human lives and the environment. No action that FEMA can anticipate under this rule will have a... to reduce damage to lives, property, and the economy from future disasters. State, Tribal, and local... funding for eligible mitigation activities that reduce disaster losses and protect life and property from...

Exposure and Human Health Evaluation of Airborne Pollution from the World Trade Center Disaster (External Review Draft)

EPA Science Inventory

Following the collapse of the World Trade Center towers on September 11, 2001, New York State and Federal agencies initiated numerous air monitoring activities to better understand the ongoing impact of emissions from the disaster. This report focuses on these air measurement da...

Spatial econometric model of natural disaster impacts on human migration in vulnerable regions of Mexico.

PubMed

Saldaña-Zorrilla, Sergio O; Sandberg, Krister

2009-10-01

Mexico's vast human and environmental diversity offers an initial framework for comprehending some of the prevailing great disparities between rich and poor. Its socio-economic constructed vulnerability to climatic events serves to expand this understanding. Based on a spatial econometric model, this paper tests the contribution of natural disasters to stimulating the emigration process in vulnerable regions of Mexico. Besides coping and adaptive capacity, it assesses the effects of economic losses due to disasters as well as the adverse production and trade conditions of the 1990s on emigration rates in 2000 at the municipality level. Weather-related disasters were responsible for approximately 80 per cent of economic losses in Mexico between 1980 and 2005, mostly in the agricultural sector, which continues to dominate many parts of the country. It is dramatic that this sector generates around only four per cent of gross domestic product but provides a livelihood to about one-quarter of the national population. It is no wonder, therefore, that most emigration from this country arises in vulnerable rural areas.

Mass Fatality Management following the South Asian Tsunami Disaster: Case Studies in Thailand, Indonesia, and Sri Lanka

PubMed Central

Morgan, Oliver W; Sribanditmongkol, Pongruk; Perera, Clifford; Sulasmi, Yeddi; Van Alphen, Dana; Sondorp, Egbert

2006-01-01

Background Following natural disasters, mismanagement of the dead has consequences for the psychological well-being of survivors. However, no technical guidelines currently exist for managing mass fatalities following large natural disasters. Existing methods of mass fatality management are not directly transferable as they are designed for transport accidents and acts of terrorism. Furthermore, no information is currently available about post-disaster management of the dead following previous large natural disasters. Methods and Findings After the tsunami disaster on 26 December 2004, we conducted three descriptive case studies to systematically document how the dead were managed in Thailand, Indonesia, and Sri Lanka. We considered the following parameters: body recovery and storage, identification, disposal of human remains, and health risks from dead bodies. We used participant observations as members of post-tsunami response teams, conducted semi-structured interviews with key informants, and collected information from published and unpublished documents. Refrigeration for preserving human remains was not available soon enough after the disaster, necessitating the use of other methods such as dry ice or temporary burial. No country had sufficient forensic capacity to identify thousands of victims. Rapid decomposition made visual identification almost impossible after 24–48 h. In Thailand, most forensic identification was made using dental and fingerprint data. Few victims were identified from DNA. Lack of national or local mass fatality plans further limited the quality and timeliness of response, a problem which was exacerbated by the absence of practical field guidelines or an international agency providing technical support. Conclusions Emergency response should not add to the distress of affected communities by inappropriately disposing of the victims. The rights of survivors to see their dead treated with dignity and respect requires practical guidelines and technical support. Mass fatality management following natural disasters needs to be informed by further field research and supported by a network of regional and international forensic institutes and agencies. PMID:16737348

Mass fatality management following the South Asian tsunami disaster: case studies in Thailand, Indonesia, and Sri Lanka.

PubMed

Morgan, Oliver W; Sribanditmongkol, Pongruk; Perera, Clifford; Sulasmi, Yeddi; Van Alphen, Dana; Sondorp, Egbert

2006-06-01

Following natural disasters, mismanagement of the dead has consequences for the psychological well-being of survivors. However, no technical guidelines currently exist for managing mass fatalities following large natural disasters. Existing methods of mass fatality management are not directly transferable as they are designed for transport accidents and acts of terrorism. Furthermore, no information is currently available about post-disaster management of the dead following previous large natural disasters. After the tsunami disaster on 26 December 2004, we conducted three descriptive case studies to systematically document how the dead were managed in Thailand, Indonesia, and Sri Lanka. We considered the following parameters: body recovery and storage, identification, disposal of human remains, and health risks from dead bodies. We used participant observations as members of post-tsunami response teams, conducted semi-structured interviews with key informants, and collected information from published and unpublished documents. Refrigeration for preserving human remains was not available soon enough after the disaster, necessitating the use of other methods such as dry ice or temporary burial. No country had sufficient forensic capacity to identify thousands of victims. Rapid decomposition made visual identification almost impossible after 24-48 h. In Thailand, most forensic identification was made using dental and fingerprint data. Few victims were identified from DNA. Lack of national or local mass fatality plans further limited the quality and timeliness of response, a problem which was exacerbated by the absence of practical field guidelines or an international agency providing technical support. Emergency response should not add to the distress of affected communities by inappropriately disposing of the victims. The rights of survivors to see their dead treated with dignity and respect requires practical guidelines and technical support. Mass fatality management following natural disasters needs to be informed by further field research and supported by a network of regional and international forensic institutes and agencies.

Flood Disaster Risk Reduction in municipality-scale in Rio de Janeiro State

NASA Astrophysics Data System (ADS)

Japiassú Viana, Viviane; Formiga Johnsson, Rosa Maria; De Gouvello, Bernard

2015-04-01

In Brazil, flood disasters causing human damage, pecuniary loss and environmental damage, are mainly due to greater exposure of the population; urban densification on the riverbanks and margins, incurring vulnerability due to changes in river level and climate changes. This article presents the data and studies required in the Brazilian legal basis and analyzes the scales adopted by planners in contrast to the scales demands by the executing agencies in the context of prevention and adaptation to climate change, particularly to flood disaster reduction in municipality-scale.

Unnatural deaths in Shanghai from 2000 to 2009: a retrospective study of forensic autopsy cases at the Shanghai Public Security Bureau.

PubMed

He, Meng; Fang, You-Xin; Lin, Jun-Yi; Ma, Kai-Jun; Li, Bei-Xu

2015-01-01

Shanghai is the most developed city in China and has a soaring population. This study uses forensic epidemiology to determine the relationship between unnatural deaths and the development in Shanghai, based on recently released forensic autopsy cases from the 2000s at the Shanghai Public Security Bureau (SPSB). There were 5425 accidental deaths, 2696 homicides, 429 suicides, 186 natural deaths, and 1399 deaths of undetermined cause. There was a male-to-female ratio of 2.02:1, and the average age was 40.9±18.7 years. Traffic accidents (84.2%) were the number one cause of accidental deaths, which decreased during the study period. Sharp force injury (50.6%) was the leading cause of homicides, different from Western countries, where firearms are the leading cause. Hanging (24.5%) was the leading cause of suicides, whereas drug and chemical intoxication was the leading cause in the previous decade; pesticide ingestion decreased in the 2000s. In addition to traffic accidents, manual strangulation was the leading cause of death in childhood fatalities. Children under age 2 were vulnerable to homicides. In the 2000s, there were a large number of drug overdoses, and illegal medical practices and subway-related deaths first appeared in Shanghai. A new type of terrorist attack that involved injecting people with syringes in public places was reflected in the SPSB archives. The forensic epidemiology and changes in unnatural deaths in this decade reflected their relationship with the law, policy and changes in Shanghai. Illegal medical practices, subway-related deaths and terrorist attacks were closely related to the development in Shanghai. Identifying the risks of unnatural deaths will improve public health.

Unnatural Deaths in Shanghai from 2000 to 2009: A Retrospective Study of Forensic Autopsy Cases at the Shanghai Public Security Bureau

PubMed Central

Lin, Jun-Yi; Ma, Kai-Jun; Li, Bei-Xu

2015-01-01

Shanghai is the most developed city in China and has a soaring population. This study uses forensic epidemiology to determine the relationship between unnatural deaths and the development in Shanghai, based on recently released forensic autopsy cases from the 2000s at the Shanghai Public Security Bureau (SPSB). There were 5425 accidental deaths, 2696 homicides, 429 suicides, 186 natural deaths, and 1399 deaths of undetermined cause. There was a male-to-female ratio of 2.02:1, and the average age was 40.9±18.7 years. Traffic accidents (84.2%) were the number one cause of accidental deaths, which decreased during the study period. Sharp force injury (50.6%) was the leading cause of homicides, different from Western countries, where firearms are the leading cause. Hanging (24.5%) was the leading cause of suicides, whereas drug and chemical intoxication was the leading cause in the previous decade; pesticide ingestion decreased in the 2000s. In addition to traffic accidents, manual strangulation was the leading cause of death in childhood fatalities. Children under age 2 were vulnerable to homicides. In the 2000s, there were a large number of drug overdoses, and illegal medical practices and subway-related deaths first appeared in Shanghai. A new type of terrorist attack that involved injecting people with syringes in public places was reflected in the SPSB archives. The forensic epidemiology and changes in unnatural deaths in this decade reflected their relationship with the law, policy and changes in Shanghai. Illegal medical practices, subway-related deaths and terrorist attacks were closely related to the development in Shanghai. Identifying the risks of unnatural deaths will improve public health. PMID:26110435

Commonalities between Disaster and Climate Change Risks for Health: A Theoretical Framework.

PubMed

Banwell, Nicola; Rutherford, Shannon; Mackey, Brendan; Street, Roger; Chu, Cordia

2018-03-16

Disasters and climate change have significant implications for human health worldwide. Both climate change and the climate-sensitive hazards that result in disasters, are discussed in terms of direct and indirect impacts on health. A growing body of literature has argued for the need to link disaster risk reduction and climate change adaptation. However, there is limited articulation of the commonalities between these health impacts. Understanding the shared risk pathways is an important starting point for developing joint strategies for adapting to, and reducing, health risks. Therefore, this article discusses the common aspects of direct and indirect health risks of climate change and climate-sensitive disasters. Based on this discussion a theoretical framework is presented for understanding these commonalities. As such, this article hopes to extend the current health impact frameworks and provide a platform for further research exploring opportunities for linked adaptation and risk reduction strategies.

Commonalities between Disaster and Climate Change Risks for Health: A Theoretical Framework

PubMed Central

Banwell, Nicola; Rutherford, Shannon; Mackey, Brendan; Street, Roger; Chu, Cordia

2018-01-01

Disasters and climate change have significant implications for human health worldwide. Both climate change and the climate-sensitive hazards that result in disasters, are discussed in terms of direct and indirect impacts on health. A growing body of literature has argued for the need to link disaster risk reduction and climate change adaptation. However, there is limited articulation of the commonalities between these health impacts. Understanding the shared risk pathways is an important starting point for developing joint strategies for adapting to, and reducing, health risks. Therefore, this article discusses the common aspects of direct and indirect health risks of climate change and climate-sensitive disasters. Based on this discussion a theoretical framework is presented for understanding these commonalities. As such, this article hopes to extend the current health impact frameworks and provide a platform for further research exploring opportunities for linked adaptation and risk reduction strategies. PMID:29547592

Dynamic Resource Allocation in Disaster Response: Tradeoffs in Wildfire Suppression

PubMed Central

Petrovic, Nada; Alderson, David L.; Carlson, Jean M.

2012-01-01

Challenges associated with the allocation of limited resources to mitigate the impact of natural disasters inspire fundamentally new theoretical questions for dynamic decision making in coupled human and natural systems. Wildfires are one of several types of disaster phenomena, including oil spills and disease epidemics, where (1) the disaster evolves on the same timescale as the response effort, and (2) delays in response can lead to increased disaster severity and thus greater demand for resources. We introduce a minimal stochastic process to represent wildfire progression that nonetheless accurately captures the heavy tailed statistical distribution of fire sizes observed in nature. We then couple this model for fire spread to a series of response models that isolate fundamental tradeoffs both in the strength and timing of response and also in division of limited resources across multiple competing suppression efforts. Using this framework, we compute optimal strategies for decision making scenarios that arise in fire response policy. PMID:22514605

Visualizing disaster attitudes resulting from terrorist activities.

PubMed

Khalid, Halimahtun M; Helander, Martin G; Hood, Nilwan A

2013-09-01

The purpose of this study was to analyze people's attitudes to disasters by investigating how people feel, behave and think during disasters. We focused on disasters induced by humans, such as terrorist attacks. Two types of textual information were collected - from Internet blogs and from research papers. The analysis enabled forecasting of attitudes for the design of proactive disaster advisory scheme. Text was analyzed using a text mining tool, Leximancer. The outcome of this analysis revealed core themes and concepts in the text concerning people's attitudes. The themes and concepts were sorted into three broad categories: Affect, Behaviour, and Cognition (ABC), and the data was visualized in semantic maps. The maps reveal several knowledge pathways of ABC for developing attitudinal ontologies, which describe the relations between affect, behaviour and cognition, and the sequence in which they develop. Clearly, terrorist attacks induced trauma and people became highly vulnerable. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Report focuses on improving resilience to disasters

NASA Astrophysics Data System (ADS)

Showstack, Randy

2012-08-01

“Disaster resilience is everyone's business,” states a new report that calls for a series of local and national measures to increase resilience in the face of an increasingly costly toll from natural disasters to human lives and the economy. In 2011 natural disasters were responsible for damages in the United States exceeding $55 billion, and costs could increase with more people and structures located in harm's way and with the effects of extreme events, according to the report, Disaster Resilience: A National Imperative, issued by a committee of the U.S. National Academies on 1 August. Among the recommendations is for federal government agencies to incorporate national resilience as an organizing principle to guide federal government actions and programs. The report defines resilience as “the ability to prepare and plan for, absorb, recover from, and more successfully adapt to adverse events.”

Surgical Care Required for Populations Affected by Climate-related Natural Disasters: A Global Estimation.

PubMed

Lee, Eugenia E; Stewart, Barclay; Zha, Yuanting A; Groen, Thomas A; Burkle, Frederick M; Kushner, Adam L

2016-08-10

Climate extremes will increase the frequency and severity of natural disasters worldwide.  Climate-related natural disasters were anticipated to affect 375 million people in 2015, more than 50% greater than the yearly average in the previous decade. To inform surgical assistance preparedness, we estimated the number of surgical procedures needed.   The numbers of people affected by climate-related disasters from 2004 to 2014 were obtained from the Centre for Research of the Epidemiology of Disasters database. Using 5,000 procedures per 100,000 persons as the minimum, baseline estimates were calculated. A linear regression of the number of surgical procedures performed annually and the estimated number of surgical procedures required for climate-related natural disasters was performed. Approximately 140 million people were affected by climate-related natural disasters annually requiring 7.0 million surgical procedures. The greatest need for surgical care was in the People's Republic of China, India, and the Philippines. Linear regression demonstrated a poor relationship between national surgical capacity and estimated need for surgical care resulting from natural disaster, but countries with the least surgical capacity will have the greatest need for surgical care for persons affected by climate-related natural disasters. As climate extremes increase the frequency and severity of natural disasters, millions will need surgical care beyond baseline needs. Countries with insufficient surgical capacity will have the most need for surgical care for persons affected by climate-related natural disasters. Estimates of surgical are particularly important for countries least equipped to meet surgical care demands given critical human and physical resource deficiencies.

Focusing on the human factor in environmental disasters

NASA Astrophysics Data System (ADS)

Showstack, Randy

2013-01-01

"When I wake up in the morning, I'm wondering, Is this going to be the day for the `aha,' when leaders around the country will come to grips with the problems that are there in front of them and be responsive to the information they already have?" Gerald Galloway, an expert in water resource policy and civil engineering, said during a 16 January discussion about human factors in disasters. The discussion was part of the 13th National Conference on Science, Policy and the Environment, held in Washington, D. C.

Structural and kinetic analysis of the unnatural fusion protein 4-coumaroyl-CoA ligase::stilbene synthase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Yechun; Yi, Hankuil; Wang, Melissa

2012-10-24

To increase the biochemical efficiency of biosynthetic systems, metabolic engineers have explored different approaches for organizing enzymes, including the generation of unnatural fusion proteins. Previous work aimed at improving the biosynthesis of resveratrol, a stilbene associated a range of health-promoting activities, in yeast used an unnatural engineered fusion protein of Arabidopsis thaliana (thale cress) 4-coumaroyl-CoA ligase (At4CL1) and Vitis vinifera (grape) stilbene synthase (VvSTS) to increase resveratrol levels 15-fold relative to yeast expressing the individual enzymes. Here we present the crystallographic and biochemical analysis of the 4CL::STS fusion protein. Determination of the X-ray crystal structure of 4CL::STS provides the firstmore » molecular view of an artificial didomain adenylation/ketosynthase fusion protein. Comparison of the steady-state kinetic properties of At4CL1, VvSTS, and 4CL::STS demonstrates that the fusion protein improves catalytic efficiency of either reaction less than 3-fold. Structural and kinetic analysis suggests that colocalization of the two enzyme active sites within 70 {angstrom} of each other provides the basis for enhanced in vivo synthesis of resveratrol.« less

Fluorescence enhancement of fluorescent unnatural streptavidin by binding of a biotin analogue with spacer tail and its application to biotin sensing.

PubMed

Zhu, Xianwei; Shinohara, Hiroaki

2014-01-01

We designed a novel molecular biosensing system for the detection of biotin, an important vitamin by the combination of fluorescent unnatural streptavidin with a commercialized biotin-(AC5)2-hydrazide. A fluorescent unnatural amino acid, BODIPY-FL-aminophenylalanine (BFLAF), was position-specifically incorporated into Trp120 of streptavidin by four-base codon method. Fluorescence of the Trp120BFLAF mutant streptavidin was enhanced by the addition of biotin-(AC5)2-hydrazide with the concentration dependent, whereas fluorescence enhancement was not observed at all by the addition of natural biotin. It was considered that the spacer tail of biotin-(AC5)2-hydrazide may disturb the fluorescence quenching of the Trp120BFLAF by Trp79 and Trp108 of the neighbor subunit. Therefore, biotin sensing was carried out by the competitive binding reaction of biotin-(AC5)2-hydrazide and natural biotin to the fluorescent mutant streptavidin. The fluorescence intensity decreased by increasing free biotin concentration. The result suggested that molecular biosensor for small ligand could be successfully designed by the pair of fluorescent mutant binding protein and ligand analogue.

Unnatural selection in chemical systems

NASA Technical Reports Server (NTRS)

Orgel, Leslie E.

1995-01-01

The theory of evolution through natural selection was proposed by Darwin and Wallace to explain how the characteristics of populations of animals change with time. An examination of their assumptions shows that the theory has much broader application than they originally envisaged. We now know that in appropriate environments RNA molecules or computer viruses, for example, can evolve. The adventure with which we are concerned is the quest for chemical systems that undergo processes analogous to Darwinian selection in the test tube. The search is not restricted to systems that are closely related to nucleic acids, although most of the available experimental evidence concerns such systems. A population of molecules satisfies all the requirements of the theory is there are different kinds of molecules in the population and if each individual molecule can direct the formation of copies of itself, then a population of molecules will adapt to a varying environment by changing its composition so as to maintain as high as possible a rate of replication. Sol Spiegelman is the inventor of 'unnatural selection'. He showed clearly that populations of RNA molecules evolve when replicated repeatedly by Q beta RNA polymerase under a chosen set of adverse reaction conditions. In the systems that he studied, the initial population was fairly homogeneous and much of the variation was created during the course of the experiment by mutation, that is, error of replication. The term 'unnatural selection' will be used loosely to describe evolution of nucleic acids or other replicatable polymers in vitro. The term 'Natural Selection' will be reserved for the evolution of living organisms and their viruses. Natural Section usually involves the coevolution of nucleic acids and proteins, while 'unnatural selection', as practiced so far, allows replicating nucleic acids to evolve but hold constant the enzymes that catalyze replication. It is widely believed that biology based on DNA, RNA, and proteins was preceded by the biology of an 'RNA world' in which enzymes were composed of RNA alone. The origin of RNA replication is thus the central puzzle of the origins of life. Consequently, RNA-catalyzed RNA replication is presently one of the main goals of experimental work on unnatural selection. However, there is also a more distant goal, namely, to achieve replication and selection in systems unrelated to RNA. These different systems are discussed in this article.

"We're All Gonna' Die": Using Human Interest in Disasters to Promote Student Interest and Research in Introductory Science Classes for Non-Science Majors.

NASA Astrophysics Data System (ADS)

Prueher, L.

2008-12-01

Humans are fascinated by disasters. Volcanic eruptions, earthquakes, and other natural disasters capture the public interest and provide educators a venue in which to present scientific information and dispel common misconceptions. Presenting scientific information via the vehicle of a disaster can attract even the most science-phobic student, capturing their interest in a way that more traditional methods of presentation cannot or do not. People are inundated with scientific data through the popular media yet little is done to provide non-scientists with the information needed to distinguish between fact and fiction. Docudramas such as, "Supervolcano", blur the boundary between reality and fiction. Human interest in disasters can be used as an educational tool to foster scientific literacy among non-science majors. "We're All Gonna' Die", is an inquiry-based research project used in introductory geology classes at Arapahoe Community College and the University of Northern Colorado. Most students taking this class have no college science background. The project introduces students to geological and environmental hazards. Students choose a city of interest, analyze the potential geologic and environmental hazards in the area, and determine what can be done to minimize potential damage and fatalities. Students are more interested in a topic and delve deeper into the subject matter when researching a project of their own choosing. Students have incorporated demonstrations, skits, student-made videos, games, current geologic events, and research results into their projects. Perhaps as important, the students have fun, become excited about their project and topic, and disseminate the information to family and friends.

Research in disaster settings: a systematic qualitative review of ethical guidelines.

PubMed

Mezinska, Signe; Kakuk, Péter; Mijaljica, Goran; Waligóra, Marcin; O'Mathúna, Dónal P

2016-10-21

Conducting research during or in the aftermath of disasters poses many specific practical and ethical challenges. This is particularly the case with research involving human subjects. The extraordinary circumstances of research conducted in disaster settings require appropriate regulations to ensure the protection of human participants. The goal of this study is to systematically and qualitatively review the existing ethical guidelines for disaster research by using the constant comparative method (CCM). We performed a systematic qualitative review of disaster research ethics guidelines to collect and compare existing regulations. Guidelines were identified by a three-tiered search strategy: 1) searching databases (PubMed and Google Scholar), 2) an Internet search (Google), and 3) a search of the references in the included documents from the first two searches. We used the constant comparative method (CCM) for analysis of included guidelines. Fourteen full text guidelines were included for analysis. The included guidelines covered the period 2000-2014. Qualitative analysis of the included guidelines revealed two core themes: vulnerability and research ethics committee review. Within each of the two core themes, various categories and subcategories were identified. Some concepts and terms identified in analyzed guidelines are used in an inconsistent manner and applied in different contexts. Conceptual clarity is needed in this area as well as empirical evidence to support the statements and requirements included in analyzed guidelines.

Modeling of the Geosocial Process using GIS «Disasters»

NASA Astrophysics Data System (ADS)

Vikulina, Marina; Turchaninova, Alla; Dolgaya, Anna; Vikulin, Alexandr; Petrova, Elena

2016-04-01

The natural and social disasters generate a huge stress in the world community. Most researches searching for the relationships between different catastrophic events consider the limited sets of disasters and do not take into account their size. This fact puts to doubt the completeness and statistical significance of such approach. Thus the next indispensible step is to overpass from narrow subject framework researches of disasters to more complex researches. In order to study the relationships between the Nature and the Society a database of natural disasters and dreadful social events occurred during the last XXXVI (36) centuries of human history weighted by the magnitude was created and became a core of the GIS «Disasters» (ArcGIS 10.0). By the moment the database includes more than 2500 most socially significant ("strong") catastrophic natural (earthquakes, fires, floods, droughts, climatic anomalies, other natural disasters) as well as social (wars, revolts, genocide, epidemics, fires caused by the human being, other social disasters) events. So far, each event is presented as a point feature located in the center of the struck region in the World Map. If the event affects several countries, it is placed in the approximate center of the affected area. Every event refers to the country or group of countries which are located in a zone of its influence now. The grade J (I, II and III) is specified for each event according to the disaster force assessment scale developed by the authors. The GIS with such a detailed database of disastrous events weighted by the magnitude over a long period of time is compiled for the first time and creates fairly complete and statistically representative basis for studies of the distribution of natural and social disasters and their relationship. By the moment the statistical analysis of the database performed both for each aggregate (natural disasters and catastrophic social phenomena), and for particular statistically representative types of events led to the following conclusions: natural disasters and dreadful social events have appeared to be closely related to each other despite their apparently different nature. The numbers of events of different magnitude are distributed by logarithmic law: the bigger the event, the less likely it happens. For each type of events and each aggregate the existence of periodicities with periods of 280 ± 60 years was established. The identified properties of cyclicity, grouping and interaction create a basis for modeling essentially unified Geosocial Process at a high enough statistical level and prove the existence of the uniform planetary Geosocial Process. The evidence of interaction between "lifeless" Nature and Society is fundamental and provided a new forecasting approach of demographic crises taking into account both natural disasters and social phenomena. The idea of the interaction of Nature and Society through the disasters «exchange» as a uniform planetary Geosocial Process is an essentially new statement introduced for the first time.

The experience of collective trauma in Australian Indigenous communities.

PubMed

Krieg, Anthea

2009-08-01

The concept of collective trauma has predominantly been applied in the context of natural and human disasters. This paper seeks to explore whether collective trauma offers a respectful way in which to explore and respond to mental health and wellbeing issues for Aboriginal families and communities. A review of the international literature was undertaken in order to determine the elements of collective and mass trauma studies which may have relevance for Indigenous communities in Australia. Findings support the proposition that the patterns of human responses to disasters, particularly in protracted traumas such as war-zones, shows strong parallels to the contemporary patterns of experience and responses articulated by Aboriginal people affected by colonization and its sequelae in Australia. Adopting evidence-informed principles of family and community healing developed internationally in disaster situations may provide helpful ways of conceptualizing and responding in a coordinated way to mental health and wellbeing issues for Indigenous people within Australia.

Evaluation of a new community-based curriculum in disaster medicine for undergraduates.

PubMed

Bajow, Nidaa; Djalali, Ahmadreza; Ingrassia, Pier Luigi; Ragazzoni, Luca; Ageely, Hussein; Bani, Ibrahim; Corte, Francesco Della

2016-08-26

Nowadays, many medical schools include training in disaster medicine in undergraduate studies. This study evaluated the efficacy of a disaster medicine curriculum recently designed for Saudi Arabian medical students. Participants were 15 male and 14 female students in their fourth, fifth or sixth year at Jazan University Medical School, Saudi Arabia. The course was held at the Research Center in Emergency and Disaster Medicine and Computer Sciences Applied to the Medical Practice in Novara, Italy. The overall mean score on a test given before the course was 41.0 % and it increased to 67.7 % on the post-test (Wilcoxon test for paired samples: z = 4.71, p < 0.0001). There were no significant differences between the mean scores of males and females, or between students in their fourth, fifth or sixth year of medical school. These results show that this curriculum is effective for teaching disaster medicine to undergraduate medical students. Adoption of this course would help to increase the human resources available for dealing with disaster situations.

Integrating social media and remote sensing data in a model framework to identify vulnerable areas in coastal cities after disasters

NASA Astrophysics Data System (ADS)

Gopalakrishnan, G.

2013-12-01

In the aftermath of man-made disasters such as oil spills or natural disasters such as hurricanes and floods, city planners and residents of affected areas are often concerned about future vulnerabilities and rebuilding the area to increase resilience. However, identifying locations in the affected area that are most impacted by the disaster, the associated human health risks and potential vulnerabilities often require a monitoring effort that is expensive, time-consuming and difficult to implement in disaster-hit areas using traditional monitoring techniques. This project presents a framework for identifying areas that are most likely to be impacted by disasters by integrating remote sensing data and information from social media networks, including Twitter streams. The framework was tested for New York, coastal New Jersey and Staten Island in the aftermath of Hurricane Sandy. Vulnerable areas were identified using anomaly detection and the results were mapped against measurements collected on the ground. A correlation coefficient of 0.78 was obtained. Uncertainty in model predictions was evaluated using Monte Carlo simulations.

Disaster risk profile and existing legal framework of Nepal: floods and landslides

PubMed Central

Gaire, Surya; Castro Delgado, Rafael; Arcos González, Pedro

2015-01-01

Nepal has a complicated geophysical structure that is prone to various kinds of disasters. Nepal ranks the most disaster-prone country in the world and has experienced several natural calamities, causing high property and life losses. Disasters are caused by natural processes, but may be increased by human activities. The overall objective of this paper is to analyze the disaster risk profile and existing legal framework of Nepal. The paper is based on secondary data sources. Major causative factors for floods and landslides are heavy and continuous rainfall, outburst floods, infrastructure failure, and deforestation. Historical data of natural disasters in Nepal show that water-induced disasters have killed hundreds of people and affected thousands every year. Likewise, properties worth millions of US dollars have been damaged. There is an increasing trend toward landslides and floods, which will likely continue to rise if proper intervention is not taken. A positive correlation between water-induced disasters and deaths has been observed. Nepal has a poor Index for Risk Management (INFORM). There are fluctuations in the recording of death data caused by flood and landslides. The Government of Nepal focuses more on the response phase than on the preparedness phase of disasters. The existing disaster management act seems to be weak and outdated. There is a gap in current legal procedure, so the country is in dire need of a comprehensive legal framework. The new proposed act seems to take a much broader approach to disaster management. With a long-term vision of managing disaster risk in the country, the Government of Nepal has begun the Nepal Risk Reduction Consortium (NRRC) in collaboration with development and humanitarian partners. In order to improve the vulnerability of Nepal, an early warning system, mainstreaming disasters with development, research activities, community participation and awareness, and a rainfall monitoring system must all be a focus. PMID:26366106

Disaster risk profile and existing legal framework of Nepal: floods and landslides.

PubMed

Gaire, Surya; Castro Delgado, Rafael; Arcos González, Pedro

2015-01-01

Nepal has a complicated geophysical structure that is prone to various kinds of disasters. Nepal ranks the most disaster-prone country in the world and has experienced several natural calamities, causing high property and life losses. Disasters are caused by natural processes, but may be increased by human activities. The overall objective of this paper is to analyze the disaster risk profile and existing legal framework of Nepal. The paper is based on secondary data sources. Major causative factors for floods and landslides are heavy and continuous rainfall, outburst floods, infrastructure failure, and deforestation. Historical data of natural disasters in Nepal show that water-induced disasters have killed hundreds of people and affected thousands every year. Likewise, properties worth millions of US dollars have been damaged. There is an increasing trend toward landslides and floods, which will likely continue to rise if proper intervention is not taken. A positive correlation between water-induced disasters and deaths has been observed. Nepal has a poor Index for Risk Management (INFORM). There are fluctuations in the recording of death data caused by flood and landslides. The Government of Nepal focuses more on the response phase than on the preparedness phase of disasters. The existing disaster management act seems to be weak and outdated. There is a gap in current legal procedure, so the country is in dire need of a comprehensive legal framework. The new proposed act seems to take a much broader approach to disaster management. With a long-term vision of managing disaster risk in the country, the Government of Nepal has begun the Nepal Risk Reduction Consortium (NRRC) in collaboration with development and humanitarian partners. In order to improve the vulnerability of Nepal, an early warning system, mainstreaming disasters with development, research activities, community participation and awareness, and a rainfall monitoring system must all be a focus.

Hospital strategic preparedness planning: the new imperative.

PubMed

Ginter, Peter M; Duncan, W Jack; Abdolrasulnia, Maziar

2007-01-01

Strategic preparedness planning is an important new imperative for many hospitals. Strategic preparedness planning goes beyond traditional product/market strategic planning by focusing on disaster prevention, containment, and response roles. Hospitals, because of their unique mission, size, complexity, the types of materials they handle, and the types of patients they encounter, are especially vulnerable to natural and human-initiated disasters. In addition, when disasters occur, hospitals must develop well-conceived first responder (receiver) strategies. This paper argues the case for strategic preparedness planning for hospitals and proposes a process for this relatively new and much needed type of planning.

Disaster response and the international charter program

USGS Publications Warehouse

Stryker, Timothy; Jones, Brenda

2009-01-01

In a meeting held in Vienna, Austria in 1999, a small group of space agencies conceived and approved a program to provide emergency response satellite data to those affected by disasters anywhere in the world. The purpose of this group, which came to be known as the “International Charter - Space and Major Disasters”, is to promote cooperation among space agencies in the use of satellite data to manage crises during and after disasters. When tropical storms, floods, oil spills, earthquakes, landslides, volcanoes or fires endanger human life, the Charter member agencies provide valuable information about these events’ extent and impact.

Don't forget about the Christchurch earthquake: Lessons learned from this disaster

USGS Publications Warehouse

Hamburger, Michael W.; Mooney, Walter D.

2011-01-01

In the aftermath of the devastating magnitude-9.0 earthquake and tsunami that struck the Tohoku region of Japan on March 11, attention quickly turned away from a much smaller, but also highly destructive earthquake that struck the city of Christchurch, New Zealand, just a few weeks earlier, on Feb. 22. Both events are stark reminders of human vulnerability to natural disasters and provide a harsh reality check: Even technologically advanced countries with modern building codes are not immune from earthquake disasters. The Christchurch earthquake carried an additional message: Urban devastation can be triggered even by moderate-sized earthquakes.

Climate change and natural disasters: integrating science and practice to protect health.

PubMed

Sauerborn, Rainer; Ebi, Kristie

2012-12-17

Hydro-meteorological disasters are the focus of this paper. The authors examine, to which extent climate change increases their frequency and intensity. Review of IPCC-projections of climate-change related extreme weather events and related literature on health effects. Projections show that climate change is likely to increase the frequency, intensity, duration, and spatial distribution of a range of extreme weather events over coming decades. There is a need for strengthened collaboration between climate scientists, the health researchers and policy-makers as well as the disaster community to jointly develop adaptation strategies to protect human.

Disaster Governance for Community Resilience in Coastal Towns: Chilean Case Studies.

PubMed

Villagra, Paula; Quintana, Carolina

2017-09-14

This study aimed to further our understanding of a characteristic of Community Resilience known as Disaster Governance. Three attributes of Disaster Governance-redundancy, diversity, and overlap-were studied in four coastal towns in southern Chile that are at risk of tsunamis. Overall, we explored how different spatial structures of human settlements influence Disaster Governance. Using the Projective Mapping Technique, the distribution of emergency institutions (N = 32) and uses given to specific sites (e.g., for refuge, sanitary purposes and medical attention) were mapped. Content and GIS analyses (Directional Distribution and Kernel Density Index) were used to explore the dispersion and concentration of institutions and uses in each town. Disaster Governance was found to be highly influenced by decisions taken during regional, urban, and emergency planning. Governance is better in towns of higher order in the communal hierarchical structure. Most of the emergency institutions were found to be located in central and urban areas, which, in turn, assures more redundancy, overlap, and diversity in governance in the event of a tsunami. Lack of flexibility of emergency plans also limits governance in rural and indigenous areas. While the spatial relationships found in this study indicate that urban sectors have better Disaster Governance than rural and indigenous sectors, the influence of resource availability after tsunamis, the role and responsibility of different levels of governments, and the politics of disaster also play an important role in Disaster Governance for determining Community Resilience. These findings shed light on emergency planning and aspects of the Disaster Management cycle.

The application of unmanned aerial vehicle remote sensing for monitoring secondary geological disasters after earthquakes

NASA Astrophysics Data System (ADS)

Lei, Tianjie; Zhang, Yazhen; Wang, Xingyong; Fu, Jun'e.; Li, Lin; Pang, Zhiguo; Zhang, Xiaolei; Kan, Guangyuan

2017-07-01

Remote sensing system fitted on Unmanned Aerial Vehicle (UAV) can obtain clear images and high-resolution aerial photographs. It has advantages of strong real-time, flexibility and convenience, free from influence of external environment, low cost, low-flying under clouds and ability to work full-time. When an earthquake happened, it could go deep into the places safely and reliably which human staff can hardly approach, such as secondary geological disasters hit areas. The system can be timely precise in response to secondary geological disasters monitoring by a way of obtaining first-hand information as quickly as possible, producing a unique emergency response capacity to provide a scientific basis for overall decision-making processes. It can greatly enhance the capability of on-site disaster emergency working team in data collection and transmission. The great advantages of UAV remote sensing system played an irreplaceable role in monitoring secondary geological disaster dynamics and influences. Taking the landslides and barrier lakes for example, the paper explored the basic application and process of UAV remote sensing in the disaster emergency relief. UAV high-resolution remote sensing images had been exploited to estimate the situation of disaster-hit areas and monitor secondary geological disasters rapidly, systematically and continuously. Furthermore, a rapid quantitative assessment on the distribution and size of landslides and barrier lakes was carried out. Monitoring results could support relevant government departments and rescue teams, providing detailed and reliable scientific evidence for disaster relief and decision-making.

New Map Symbol System for Disaster Management

NASA Astrophysics Data System (ADS)

Marinova, Silvia T.

2018-05-01

In the last 10 years Bulgaria was frequently affected by natural and man-made disasters that caused considerable losses. According to the Bulgarian Disaster Management Act (2006) disaster management should be planned at local, regional and national level. Disaster protection is based on plans that include maps such as hazard maps, maps for protection, maps for evacuation planning, etc. Decision-making and cooperation between two or more neighboring municipalities or regions in crisis situation are still rendered difficult because the maps included in the plans differ in scale, colors, map symbols and cartographic design. To improve decision-making process in case of emergency and to reduce the number of human loss and property damages disaster management plans at local and regional level should be supported by detailed thematic maps created in accordance with uniform contents, map symbol system and design. The paper proposes a new symbol system for disaster management that includes a four level hierarchical classification of objects and phenomena according to their type and origin. All objects and phenomena of this classification are divided into five categories: disasters; infrastructure; protection services and infrastructure for protection; affected people and affected infrastructure; operational sites and activities. The symbols of these categories are shown with different background colors and shapes so that they are identifiable. All the symbols have simple but associative design. The new symbol system is used in the design of a series of maps for disaster management at local and regional level.

Community-Based Disaster Management: A Lesson Learned From Community Emergency Response Management in Banyumas, Indonesia

NASA Astrophysics Data System (ADS)

Pratama, A. Y.; Sariffuddin, S.

2018-02-01

This article aimed to review community-based disaster management in terms of its independent coordination and disaster management. Community resilience was tested during disaster emergency. While panic, the community is required to be viable and able to evacuate, manage logistic, collect data on damage and the victim, and coordinate with outsiders independently. The community in Gununglurah Village, Banyumas Regency which was hit by a landslide in 2015 provides a lesson learned about community based disaster management. This research used qualitative descriptive methodology with in-depth interview with 23 informants from the community, donor institution, village officers, and government officers. Through traditional and informal methods, the community implemented disaster management that was categorized into 3 mechanisms that were social, functional, and sequential mechanism. These mechanisms controlled different portion in which social mechanism holds the most important role in disaster management, then functional mechanism and sequential mechanism. Various community activities in the village equipped the community with organizational experience to manage logistic, human resource and other coordination. In 2007, in fact, there was vulnerability risk assessment done by the local government, which recommended efforts to be done by the community to reduce the disaster risk, yet it was not implemented. It was interesting to note that in spite of the independent disaster management there was a scientific assessment neglected. Based on this research, a new discussion on how to synchronize the endogenous knowledge with scientific modern knowledge was opened.

Natural Disasters (Environmental Health Student Portal)

MedlinePlus

... University Ecohealth) - Information on storms: how they affect human health and how to be prepared. Games and Activities ... Medicine National Institutes of Health U.S. Department of Health and Human Services

Himalayan Glacier Disasters: Changing Geomorphological Process Landscape, or a Changing Human Landscape?

NASA Astrophysics Data System (ADS)

Kargel, J. S.; Leonard, G. J.

2012-12-01

Recent deadly glacier-related disasters in the Himalayan-Karakoram region—the Attabad landslide and formation of glacier meltwater-fed Lake Gojal, the Gayari ice avalanche/landslide and burial of a Pakistani Army base, and the Seti River outburst disaster—beg the question of whether disasters may be on the rise. Science is not yet ready to offer a full answer, but it is an important one to resolve, because future land-use planning and mitigative measures may be affected. Natural disasters have been commonplace throughout the long human history of the Himalaya-Karakoram region. The broad outlines of the changing natural process, natural hazard, and risk environment may be established. The risk is rising rapidly primarily due to increased human presence in these once-forbidding mountains. Risk is shifting also because climate change is modifying the land surface process system. Rapidly changing glaciers cause a destabilization of the landscape. Glaciers are fundamentally a mestastable phenomenon put in motion by the high gravitational potential energies of the components of glacial systems: snow, ice, water, and debris. Any change in the climate-land-glacier system MUST result in a change in the land process system, with hazards and risks rising or falling or changing location or type. Most commonly, glacier-related disasters include a natural process cascade; as the factors affecting land surface processes and the frequency or magnitude of any one of the elements of the process cascade changes, the net hazard and risk to people changes. Otherwise similar glaciers and glacierized basins have differing sets of hazardous conditions and processes depending on whether the glacier is stable, advancing or retreating. The consequences for the overall risk to people will depend on the details of a specific glacier near a particular village or bridge or railroad. One size does not fit all. Generalizations about trends in natural hazards as related to climate change impacts on glaciers are possible, but any particular locality may buck the general trends. Hence, climate change is affecting the natural process, natural hazard, and human risk environment. However, changing glaciers exhibit a montage of different response behaviors, so the natural hazards and shifting hazards are also a montage. Overwhelmingly, changing land use has the largest impact on the natural hazard and risk environment. We will take recent examples of natural disasters--using both remote sensing data and field data-- and discuss how changing climate, the changing cryosphere, and changing human relationships to the land in Himalayan realms may have contributed to or altered those events.

Community strengthening and mental health system linking after flooding in two informal human settlements in Peru: a model for small-scale disaster response.

PubMed

Contreras, C; Aguilar, M; Eappen, B; Guzmán, C; Carrasco, P; Millones, A K; Galea, J T

2018-01-01

Mental health is an important factor in responding to natural disasters. Observations of unmet mental health needs motivated the subsequent development of a community-based mental health intervention following one such disaster affecting Peru in 2017. Two informal human settlements on the outskirts of Lima were selected for a mental health intervention that included: (1) screening for depression and domestic violence, (2) children's activities to strengthen social and emotional skills and diminish stress, (3) participatory theater activities to support conflict resolution and community resilience, and (4) community health worker (CHW) accompaniment to government health services. A total of 129 people were screened across both conditions, of whom 12/116 (10%) presented with depression and 21/58 (36%) reported domestic violence. 27 unique individuals were identified with at least one problem. Thirteen people (48%) initially accepted CHW accompaniment to government-provided services. This intervention provides a model for a small-scale response to disasters that can effectively and acceptably identify individuals in need of mental health services and link them to a health system that may otherwise remain inaccessible.

The Typhoon Disaster Analysis Based on Weibo Topic Heat

NASA Astrophysics Data System (ADS)

Yuan, J.; Gong, A.; Wang, J.; Li, J.

2018-04-01

Could social media data be utilized in hazard evaluation? Typhoon disaster as one of the costly disaster has become devastating threats for human. Moreover, social media change the communication way of human and citizens can turn to this platform to express disasterrelated information at real time. Therefore, social media improves situational awareness and widens the method of hazard information acquiring. With more and more studies investigating in relationship between social media response and degree of damage, the strong correlation has been proved. Weibo as one of the most popular social media in China can provide data with posted text, location, user identification and other additional information. Combining with 10 tropical cyclones and Weibo data in 2013, We perform a quantitative analysis between the grade of hazard situation and Weibo related topic heat in province scale. We provide a new model of Weibo topic heat to evaluate the Weibo activity in study area. Also we demonstrate the hazard assessing formula is H = 1.8845 ln(α) + 15.636 in tropical cyclone disaster. High level goodness of curve fitting also suggest that this equation can be used for rapid assessment of hazard caused by tropical cyclones.

A high-throughput LC-MS/MS screen for GHRP in equine and human urine, featuring peptide derivatization for improved chromatography.

PubMed

Timms, Mark; Hall, Nikki; Levina, Vita; Vine, John; Steel, Rohan

2014-10-01

The growth hormone releasing peptides (GHRPs) hexarelin, ipamorelin, alexamorelin, GHRP-1, GHRP-2, GHRP-4, GHRP-5, and GHRP-6 are all synthetic met-enkephalin analogues that include unnatural D-amino acids. They were designed specifically for their ability to stimulate growth hormone release and may serve as performance enhancing drugs. To regulate the use of these peptides within the horse racing industry and by human athletes, a method is presented for the extraction, derivatization, and detection of GHRPs from equine and human urine. This method takes advantage of a highly specific solid-phase extraction combined with a novel derivatization method to improve the chromatography of basic peptides. The method was validated with respect to linearity, repeatability, intermediate precision, specificity, limits of detection, limits of confirmation, ion suppression, and stability. As proof of principle, all eight GHRPs or their metabolites could be detected in urine collected from rats after intravenous administration. Copyright © 2014 John Wiley & Sons, Ltd.

Coordinated Control of Three-Dimensional Components of Smooth Pursuit to Rotating and Translating Textures.

PubMed

Edinger, Janick; Pai, Dinesh K; Spering, Miriam

2017-01-01

The neural control of pursuit eye movements to visual textures that simultaneously translate and rotate has largely been neglected. Here we propose that pursuit of such targets-texture pursuit-is a fully three-dimensional task that utilizes all three degrees of freedom of the eye, including torsion. Head-fixed healthy human adults (n = 8) tracked a translating and rotating random dot pattern, shown on a computer monitor, with their eyes. Horizontal, vertical, and torsional eye positions were recorded with a head-mounted eye tracker. The torsional component of pursuit is a function of the rotation of the texture, aligned with its visual properties. We observed distinct behaviors between those trials in which stimulus rotation was in the same direction as that of a rolling ball ("natural") in comparison to those with the opposite rotation ("unnatural"): Natural rotation enhanced and unnatural rotation reversed torsional velocity during pursuit, as compared to torsion triggered by a nonrotating random dot pattern. Natural rotation also triggered pursuit with a higher horizontal velocity gain and fewer and smaller corrective saccades. Furthermore, we show that horizontal corrective saccades are synchronized with torsional corrective saccades, indicating temporal coupling of horizontal and torsional saccade control. Pursuit eye movements have a torsional component that depends on the visual stimulus. Horizontal and torsional eye movements are separated in the motor periphery. Our findings suggest that translational and rotational motion signals might be coordinated in descending pursuit pathways.

Course Descriptions in Environmental Studies Part Two: Interdisciplinary Courses.

ERIC Educational Resources Information Center

Dunlap, Riley; And Others

1984-01-01

Presents descriptions (syllabi, outlines, goals) of interdisciplinary environmental studies courses. Topic areas of these courses include: environmental sociology; human ecology (politics, institutions, and the environment); humans and the environment in historical perspective; environmental management; humans, hazards, and disasters; and other…

GLOBAL DISASTERS: Geodynamics and Society

NASA Astrophysics Data System (ADS)

Vikulina, Marina; Vikulin, Alexander; Semenets, Nikolai

2013-04-01

The problem of reducing the damage caused by geodynamic and social disasters is a high priority and urgent task facing the humanity. The vivid examples of the earthquake in Japan in March 2011 that generated a new kind of threat - the radiation pollution, and the events in the Arabic world that began in the same year, are dramatic evidences. By the middle of this century, the damage from such disastrous events is supposed to exceed the combined GDP of all countries of the world. The database of 287 large-scale natural and social disasters and global social phenomena that have occurred in the period of II B.C.E. - XXI A.D. was compiled by the authors for the first time. We have proposed the following phenomenological model: the scale of disasters over the time does not decrease, there is a minimum of accidents in the XV century; the numbers of accidents have cycles lasting until the first thousand years, natural and social disasters in the aggregate are uniformly distributed in time, but separately natural and social disasters are nonuniform. Thus, due to the evaluation, a 500-year cycle of catastrophes and 200-300 and 700-800-year periodicities are identified. It is shown that catastrophes are grouped into natural and social types by forming clusters. The hypothesis of the united geo-bio-social planetary process is founded. A fundamentally new feature of this research is the assumptions about the statistical significance of the biosphere and the impact of society on the geodynamic processes. The results allow to formulate a new understanding of global disaster as an event the damage from which the humanity will be unable to liquidate even by means of the total resource potential and the consequence of which may turn into the irreversible destruction of civilization. The correlation between the natural and social phenomena and the possible action mechanism is suggested.

No Calm After the Storm: A Systematic Review of Human Health Following Flood and Storm Disasters.

PubMed

Saulnier, Dell D; Brolin Ribacke, Kim; von Schreeb, Johan

2017-10-01

Introduction How the burden of disease varies during different phases after floods and after storms is essential in order to guide a medical response, but it has not been well-described. The objective of this review was to elucidate the health problems following flood and storm disasters. A literature search of the databases Medline (US National Library of Medicine, National Institutes of Health; Bethesda, Maryland USA); Cinahl (EBSCO Information Services; Ipswich, Massachusetts USA); Global Health (EBSCO Information Services; Ipswich, Massachusetts USA); Web of Science Core Collection (Thomson Reuters; New York, New York USA); Embase (Elsevier; Amsterdam, Netherlands); and PubMed (National Center for Biotechnology Information, National Institutes of Health; Bethesda, Maryland USA) was conducted in June 2015 for English-language research articles on morbidity or mortality and flood or storm disasters. Articles on mental health, interventions, and rescue or health care workers were excluded. Data were extracted from articles that met the eligibility criteria and analyzed by narrative synthesis. The review included 113 studies. Poisonings, wounds, gastrointestinal infections, and skin or soft tissue infections all increased after storms. Gastrointestinal infections were more frequent after floods. Leptospirosis and diabetes-related complications increased after both. The majority of changes occurred within four weeks of floods or storms. Health changes differently after floods and after storms. There is a lack of data on the health effects of floods alone, long-term changes in health, and the strength of the association between disasters and health problems. This review highlights areas of consideration for medical response and the need for high-quality, systematic research in this area. Saulnier DD , Brolin Ribacke K , von Schreeb J . No calm after the storm: a systematic review of human health following flood and storm disasters. Prehosp Disaster Med. 2017;32(5):568-579.

Long-term monitoring on environmental disasters using multi-source remote sensing technique

NASA Astrophysics Data System (ADS)

Kuo, Y. C.; Chen, C. F.

2017-12-01

Environmental disasters are extreme events within the earth's system that cause deaths and injuries to humans, as well as causing damages and losses of valuable assets, such as buildings, communication systems, farmlands, forest and etc. In disaster management, a large amount of multi-temporal spatial data is required. Multi-source remote sensing data with different spatial, spectral and temporal resolutions is widely applied on environmental disaster monitoring. With multi-source and multi-temporal high resolution images, we conduct rapid, systematic and seriate observations regarding to economic damages and environmental disasters on earth. It is based on three monitoring platforms: remote sensing, UAS (Unmanned Aircraft Systems) and ground investigation. The advantages of using UAS technology include great mobility and availability in real-time rapid and more flexible weather conditions. The system can produce long-term spatial distribution information from environmental disasters, obtaining high-resolution remote sensing data and field verification data in key monitoring areas. It also supports the prevention and control on ocean pollutions, illegally disposed wastes and pine pests in different scales. Meanwhile, digital photogrammetry can be applied on the camera inside and outside the position parameters to produce Digital Surface Model (DSM) data. The latest terrain environment information is simulated by using DSM data, and can be used as references in disaster recovery in the future.

Setting Foundations for Developing Disaster Response Metrics.

PubMed

Abir, Mahshid; Bell, Sue Anne; Puppala, Neha; Awad, Osama; Moore, Melinda

2017-08-01

There are few reported efforts to define universal disaster response performance measures. Careful examination of responses to past disasters can inform the development of such measures. As a first step toward this goal, we conducted a literature review to identify key factors in responses to 3 recent events with significant loss of human life and economic impact: the 2003 Bam, Iran, earthquake; the 2004 Indian Ocean tsunami; and the 2010 Haiti earthquake. Using the PubMed (National Library of Medicine, Bethesda, MD) database, we identified 710 articles and retained 124 after applying inclusion and exclusion criteria. Seventy-two articles pertained to the Haiti earthquake, 38 to the Indian Ocean tsunami, and 14 to the Bam earthquake. On the basis of this review, we developed an organizational framework for disaster response performance measurement with 5 key disaster response categories: (1) personnel, (2) supplies and equipment, (3) transportation, (4) timeliness and efficiency, and (5) interagency cooperation. Under each of these, and again informed by the literature, we identified subcategories and specific items that could be developed into standardized performance measures. The validity and comprehensiveness of these measures can be tested by applying them to other recent and future disaster responses, after which standardized performance measures can be developed through a consensus process. (Disaster Med Public Health Preparedness. 2017;11:505-509).

Supporting Disaster Assessment and Response with the VIIRS Day-Night Band

NASA Technical Reports Server (NTRS)

Schultz, Lori A.; Cole, Tony; Molthan, Andrew L.

2015-01-01

When meteorological or man-made disasters occur, first responders often focus on impacts to the affected population and other human activities. Often, these disasters result in significant impacts to local infrastructure and power, resulting in widespread power outages. For minor events, these power outages are often short-lived, but major disasters often include long-term outages that have a significant impact on wellness, safety, and recovery efforts within the affected areas. Staff at NASA's Short-term Prediction Research and Transition (SPoRT) Center have been investigating the use of the VIIRS day-night band for monitoring power outages that result from significant disasters, and developing techniques to identify damaged areas in near real-time following events. In addition to immediate assessment, the VIIRS DNB can be used to monitor and assess ongoing recovery efforts. In this presentation, we will highlight previous applications of the VIIRS DNB following Superstorm Sandy in 2012, and other applications of the VIIRS DNB to more recent disaster events, including detection of outages following the Moore, Oklahoma tornado of May 2013 and the Chilean earthquake of April 2014. Examples of current products will be shown, along with future work and other goals for supporting disaster assessment and response with VIIRS capabilities.

U.S. consumers attitudes toward farm animal cloning.

PubMed

Brooks, Kathleen R; Lusk, Jayson L

2011-10-01

In January 2008, the United States Food and Drug Administration concluded "meat and milk from cattle, swine, and goat clones or their offspring are as safe to eat as food we eat from those species now" (U.S. FDA, 2010). However, cloning remains a very controversial topic. A web-based survey administered by Knowledge Networks was used to determine U.S. consumers' awareness of and attitudes toward meat and milk from cloned cattle. Findings reveal consumers do not differentiate much between products from cloned animals and products from non-cloned animals. Overall consumers are concerned that animal cloning is an unnatural process and that it will lead to human cloning. Copyright © 2011 Elsevier Ltd. All rights reserved.

"Unnatural" thoughts? On moral enhancement of the human animal.

PubMed

Swazo, Norman K

2017-09-01

Recent discussions about moral enhancement presuppose and recommend sets of values that relate to both the Western tradition of moral philosophy and contemporary empirical results of natural and social sciences, including moral psychology. It is argued here that this is a typology of thought that requires a fundamental interrogation. Proponents of moral enhancement do not account for important critical analyses of moral discourse, beginning with that of Friedrich Nietzsche and continuing with more prominent twentieth century thinkers such as the poststructuralist Michel Foucault, the deconstructionist Jacques Derrida, and the moral philosopher Alasdair MacIntyre. In this paper, such analyses are taken into account to highlight the need for more fundamental philosophical interrogation of the project of moral enhancement.

Human-itarian aid? Two forms of dehumanization and willingness to help after natural disasters.

PubMed

Andrighetto, Luca; Baldissarri, Cristina; Lattanzio, Sara; Loughnan, Steve; Volpato, Chiara

2014-09-01

The present research explores the distinct effects of animalistic and mechanistic dehumanization on willingness to help natural disaster victims. We examined Japanese and Haitians, two national groups recently struck by earthquakes. We showed that Italian participants differently dehumanized the two outgroups: Japanese were attributed low human nature (dehumanized as automata), whereas Haitians were attributed low human uniqueness (dehumanized as animal-like). Ninety participants were then randomly assigned to the Japanese or Haitian target group condition. Mediation analyses showed that animalistic dehumanization decreased willingness to help Haitians, whereas mechanistic dehumanization decreased willingness to help Japanese, even when controlling for attitudes. Importantly, reduced empathy explained the effects of both forms of dehumanization on intergroup helping. © 2014 The British Psychological Society.

The social construction of disasters in the United States: A historical and cultural phenomenon.

PubMed

Neaves, Tonya T; Wachhaus, T Aaron; Royer, Grace A

Societal risks from hazards are continually increasing. Each year, disasters cause thousands of deaths and cost billions of dollars. In the first half of 2011, the United States endured countless disasters-winter snowstorms in the Midwest and Northeast; severe tornadic weather in the Mississippi, Alabama, and Missouri; flash flooding in Nashville; flooding along the Mississippi River; an earthquake on the East Coast, wildfires in Texas, and Hurricane Irene. Fundamental disaster planning is regarded as an interdisciplinary approach to develop strategies and instituting policies concerned with phases of emergency management; as such, its needs are predicated on the identification of hazards and assessment of risks. Even if the probability or intensity of risks to disasters remains fairly constant, population growth, alongside economic and infrastructural development, will unavoidably result in a concomitant increase of places prone to such events. One of the greatest barriers to emergency management efforts is the failure to fully grasp the socially and politically constructed meaning of disasters. This article investigates the ways in which language has been used historically in the American lexicon to make sense of disasters in the United States in an effort to improve communal resiliency. Serving as both an idea and experience, the terminology used to convey our/the modern-day concept of disaster is a result of a cultural artifact, ie, a given time and specific place. Tools such as Google Ngram Viewer and CASOS AutoMap are used to explore the penetration, duration, and change in disaster terminology among American English literature for more than 200 years, from 1800 to 2008, by quantifying written culture. The language of disasters is an integral part of disaster response, as talking is the primary way that most people respond to and recover from disasters. The vast majority of people are not affected by any given disaster, and so it is through discussing a disaster that people make sense of it, respond, and react to it, and fit something that is overwhelming and beyond human control into the normal order of life.

Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle.

PubMed

Anastasia, Luigi; Sampaolesi, Maurilio; Papini, Nadia; Oleari, Diego; Lamorte, Giuseppe; Tringali, Cristina; Monti, Eugenio; Galli, Daniela; Tettamanti, Guido; Cossu, Giulio; Venerando, Bruno

2006-12-01

Stem cells hold a great potential for the regeneration of damaged tissues in cardiovascular or musculoskeletal diseases. Unfortunately, problems such as limited availability, control of cell fate, and allograft rejection need to be addressed before therapeutic applications may become feasible. Generation of multipotent progenitors from adult differentiated cells could be a very attractive alternative to the limited in vitro self-renewal of several types of stem cells. In this direction, a recently synthesized unnatural purine, named reversine, has been proposed to induce reversion of adult cells to a multipotent state, which could be then converted into other cell types under appropriate stimuli. Our study suggests that reversine treatment transforms primary murine and human dermal fibroblasts into myogenic-competent cells both in vitro and in vivo. Moreover, this is the first study to demonstrate that plasticity changes arise in primary mouse and human cells following reversine exposure.

Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

PubMed Central

Kasperkiewicz, Paulina; Poreba, Marcin; Snipas, Scott J.; Lin, S. Jack; Kirchhofer, Daniel; Salvesen, Guy S.; Drag, Marcin

2015-01-01

Human neutrophil serine protease 4 (NSP4), also known as PRSS57, is a recently discovered fourth member of the neutrophil serine proteases family. Although its biological function is not precisely defined, it is suggested to regulate neutrophil response and innate immune reactions. To create optimal substrates and visualization probes for NSP4 that distinguish it from other NSPs we have employed a Hybrid Combinatorial Substrate Library approach that utilizes natural and unnatural amino acids to explore protease subsite preferences. Library results were validated by synthesizing individual substrates, leading to the identification of an optimal substrate peptide. This substrate was converted to a covalent diphenyl phosphonate probe with an embedded biotin tag. This probe demonstrated high inhibitory activity and stringent specificity and may be suitable for visualizing NSP4 in the background of other NSPs. PMID:26172376

Environmental implications for disaster preparedness: lessons learnt from the Indian Ocean Tsunami.

PubMed

Srinivas, Hari; Nakagawa, Yuko

2008-10-01

The impact of disasters, whether natural or man-made, not only has human dimensions, but environmental ones as well. Environmental conditions may exacerbate the impact of a disaster, and vice versa, disasters tend to have an impact on the environment. Deforestation, forest management practices, or agriculture systems can worsen the negative environmental impacts of a storm or typhoon, leading to landslides, flooding, silting, and ground/surface water contamination. We have only now come to understand these cyclical causes and impacts and realize that taking care of our natural resources and managing them wisely not only assures that future generations will be able to live in sustainable ways, but also reduces the risks that natural and man-made hazards pose to people living today. Emphasizing and reinforcing the centrality of environmental concerns in disaster management has become a critical priority, requiring the sound management of natural resources as a tool to prevent disasters and lessen their impacts on people, their homes, and livelihoods. As the horrors of the Asian tsunami of December 2004 continue to be evaluated, and people in the region slowly attempt to build a semblance of normalcy, we have to look to the lessons learnt from the tsunami disaster as an opportunity to prepare ourselves better for future disasters. This article focuses on findings and lessons learnt on the environmental aspects of the tsunami, and its implications on disaster preparedness plans. This article essentially emphasizes the cyclical interrelations between environments and disasters, by studying the findings and assessments of the recent Indian Ocean earthquake and tsunami that struck on 26 December 2004. It specifically looks at four key affected countries--Maldives, Sri Lanka, Indonesia, and Thailand.

Mortuary Affairs Soldiers: Early Intervention and Altering Barriers to Care for Traumatic Stress and PTSD

DTIC Science & Technology

2014-11-01

military populations and have implications for interventions with disaster workers and others exposed to the dead. Keywords US Army, soldier... military deployment can be high (Cigrang et al., 2014; Hoge et al., 2004; Prigerson, Maciejewski & Rosenheck, 2002; Ursano & Norwood, 1996...have documented the psychological effects of working with human remains on military personnel and disaster workers (Bryant & Harvey, 1996; Clohessy

Mapping the Human Planet: Integrating Settlement, Infrastructure, and Population Data to Support Sustainable Development, Climate, and Disaster Data Needs

NASA Astrophysics Data System (ADS)

Chen, R. S.; de Sherbinin, A. M.; Yetman, G.; Downs, R. R.

2017-12-01

A central issue in international efforts to address climate change, large-scale disaster risk, and overall sustainable development is the exposure of human settlements and population to changing climate patterns and a range of geological, climatological, technological, and other hazards. The present and future location of human activities is also important in mitigation and adaptation to climate change, and to ensuring that we "leave no one behind" in achieving the Sustainable Development Goals adopted by the international community in September 2015. The extent and quality of built infrastructure are key factors in the mortality, morbidity, and economic impacts of disasters, and are simultaneously essential to sustainable development. Earth observations have great potential to improve the coverage, consistency, timeliness, and richness of data on settlements, infrastructure, and population, in ways that complement existing and emerging forms of socioeconomic data collection such as censuses, surveys, and cell phone and Internet traffic. Night-time lights from the Suomi-NPP satellite may be able to provide near real-time data on occupance and economic activity. New "big data" capabilities make it possible to rapidly process high-resolution (50-cm) imagery to detect structures and changes in structures, especially in rural areas where other data are limited. A key challenge is to ensure that these types of data can be translated into forms useful in a range of applications and for diverse user communities, including national statistical offices, local government planners, development and humanitarian organizations, community groups, and the private sector. We report here on efforts, in coordination with the GEO Human Planet Initiative, to develop new data on settlements, infrastructure, and population, together with open data services and tools, to support disaster risk assessment, climate vulnerability analysis, and sustainable development decision making.

Atypical birdsong and artificial languages provide insights into how communication systems are shaped by learning, use, and transmission.

PubMed

Fehér, Olga

2017-02-01

In this article, I argue that a comparative approach focusing on the cognitive capacities and behavioral mechanisms that underlie vocal learning in songbirds and humans can provide valuable insights into the evolutionary origins of language. The experimental approaches I discuss use abnormal song and atypical linguistic input to study the processes of individual learning, social interaction, and cultural transmission. Atypical input places increased learning and communicative pressure on learners, so exploring how they respond to this type of input provides a particularly clear picture of the biases and constraints at work during learning and use. Furthermore, simulating the cultural transmission of these unnatural communication systems in the laboratory informs us about how learning and social biases influence the structure of communication systems in the long run. Findings based on these methods suggest fundamental similarities in the basic social-cognitive mechanisms underlying vocal learning in birds and humans, and continuing research promises insights into the uniquely human mechanisms and into how human cognition and social behavior interact, and ultimately impact on the evolution of language.

What is the cost of a life in a disaster? - Examples, Practice and Global Analysis

NASA Astrophysics Data System (ADS)

Daniell, James; Kunz-Plapp, Tina; Schaefer, Andreas; Wenzel, Friedemann; Khazai, Bijan

2015-04-01

An analysis is presented based on historical evidence and global exposure metrics using the CATDAT Socioeconomic databases, in order to create a global distribution of the cost of life in a disaster using various metrics. Casualty insurance models require a value of life & mitigation and cost-benefit studies require a value of life in order to make decisions and set premiums. Although this is a contentious concept, there are two general approaches to human life costing: the first is based on human capital which looks at the production capacity and potential output as a proxy for future earning; the second looks at willingness to pay which estimates people's value on reducing risk and compensation payouts. A combination approach is used. For each of the 245 nations, a value of life is estimated using the following parameters:- (1) Age of people in a country using the life expectancy and distribution data in CATDAT (2) Output of the economy and wage distribution (3) Household and community interactions (4) Lost quality of life The range of statistical life costs are examined globally from different sources, with the range of a life value being from 10,000 up to in the order of 10 million between different countries. The difference of the cost for a fatality vs. that of a severe injury is also discussed with a severe injury often having higher costs than a fatality for loss purposes. The losses in terms of historical disasters are looked at and examined with the percentage of life cost shown as a proportion of total losses. The losses of a future major earthquake in a low seismicity region show some of the largest potential life cost losses with that of a M6.8 in Adelaide, Australia; having around 160 billion in life costs (25,000 deaths, 15,000 severe injuries). This study has benefits post-disaster for quantification of human capital losses in major disasters, and pre-disaster for the analysis of insurance and mitigation options.

Measuring psychological resilience to disasters: are evidence-based indicators an achievable goal?

PubMed Central

2013-01-01

Despite rising interest on the concept of societal resilience and its measurement, little has been done to provide operational indicators. Importantly, an evidence-based approach to assess the suitability of indicators remains unexplored. Furthermore few approaches that exist do not investigate indicators of psychological resilience, which is emerging as an important component of societal resilience to disasters. Disasters are events which overwhelm local capacities, often producing human losses, injury and damage to the affected communities. As climate hazards and disasters are likely to increase in the coming decades, strengthening the capacity of societies to withstand these shocks and recover quickly is vital. In this review, we search the Web of Knowledge to summarize the evidence on indicators of psychological resilience to disasters and provided a qualitative assessment of six selected studies. We find that an evidence-based approach using features from systematic reviews is useful to compile, select and assess the evidence and elucidate robust indicators. We conclude that strong social support received after a disaster is associated with an increased psychological resilience whereas a female gender is connected with a decrease in the likelihood of a resilient outcome. These results are consistent across disaster settings and cultures and are representative of approximately 13 million disaster-exposed civilians of adult age. An approach such as this that collects and evaluates evidence will allow indicators of resilience to be much more revealing and useful in the future. They will provide a robust basis to prioritize indicators to act upon through intersectoral policies and post-disaster public health interventions. PMID:24359448

Disaster Governance for Community Resilience in Coastal Towns: Chilean Case Studies

PubMed Central

Quintana, Carolina

2017-01-01

This study aimed to further our understanding of a characteristic of Community Resilience known as Disaster Governance. Three attributes of Disaster Governance—redundancy, diversity, and overlap—were studied in four coastal towns in southern Chile that are at risk of tsunamis. Overall, we explored how different spatial structures of human settlements influence Disaster Governance. Using the Projective Mapping Technique, the distribution of emergency institutions (N = 32) and uses given to specific sites (e.g., for refuge, sanitary purposes and medical attention) were mapped. Content and GIS analyses (Directional Distribution and Kernel Density Index) were used to explore the dispersion and concentration of institutions and uses in each town. Disaster Governance was found to be highly influenced by decisions taken during regional, urban, and emergency planning. Governance is better in towns of higher order in the communal hierarchical structure. Most of the emergency institutions were found to be located in central and urban areas, which, in turn, assures more redundancy, overlap, and diversity in governance in the event of a tsunami. Lack of flexibility of emergency plans also limits governance in rural and indigenous areas. While the spatial relationships found in this study indicate that urban sectors have better Disaster Governance than rural and indigenous sectors, the influence of resource availability after tsunamis, the role and responsibility of different levels of governments, and the politics of disaster also play an important role in Disaster Governance for determining Community Resilience. These findings shed light on emergency planning and aspects of the Disaster Management cycle. PMID:28906480

Pattern of unnatural deaths among children: An autopsy study.

PubMed

Athani, Praveen; Hugar, Basappa S; Harish, S; Girishchandra, Y P

2017-06-01

This study was conducted at the M. S. Ramaiah Medical College, Bangalore, between October 2007 and September 2009 to analyse the age and sex distribution of unnatural deaths in children, patterns and manner of death. Detailed information regarding the circumstances of death was sought from the relatives, friends and police. The scene of occurrence was visited, and photographs of the scene of occurrence were examined in relevant cases. Unnatural deaths in children constituted 6.62% of the total autopsies conducted. The majority of childhood deaths were in the age group of 15-18 years of both sexes constituting 46.88%. Males constituted 55.22% of cases. Suicide accounted for 40.63% of the cases. Most children committed suicide by hanging (82.05%). The main reason was academic failure and some of the cases were accidental (48.96%). Road traffic accidents accounted for 26.04% of the cases, where most children were pedestrians (56%). Drowning accounted for 15.63% of the cases. Most of the children drowned while playing near ponds (83.33%). Homicide accounted for 9.36% of the cases - either killed by their mother as part of a pedicide-suicide event or by the father, and in two cases the children were sexually abused before being killed.

Historical floods in the Dutch Rhine Delta

NASA Astrophysics Data System (ADS)

Glaser, R.; Stangl, H.

Historical records provide direct information about the climatic impact on society. Especially great natural disasters such as river floods have been for long attracting the attention of humankind. Time series for flood development on the Rhine branches Waal, Nederrijn/Lek and IJssel in the Dutch Rhine Delta are presented in this paper. In the case of the Waal it is even possible to compare historical flood frequencies based on documentary data with the recent development reconstructed from standardized instrumental measurements. In brief, we will also discuss various parameters concerning the structure of the flood series and the "human dimension" of natural disaster, i.e. the vulnerability of society when facing natural disasters.

Climate change and natural disasters – integrating science and practice to protect health

PubMed Central

Sauerborn, Rainer; Ebi, Kristie

2012-01-01

Background Hydro-meteorological disasters are the focus of this paper. The authors examine, to which extent climate change increases their frequency and intensity. Methods Review of IPCC-projections of climate-change related extreme weather events and related literature on health effects. Results Projections show that climate change is likely to increase the frequency, intensity, duration, and spatial distribution of a range of extreme weather events over coming decades. Conclusions There is a need for strengthened collaboration between climate scientists, the health researchers and policy-makers as well as the disaster community to jointly develop adaptation strategies to protect human. PMID:23273248

What tourist business managers must learn from disaster research.

PubMed

Drabek, Thomas E

2016-01-01

Death and social disruption caused by disasters of varying forms will continue to increase in the future. So too will the impacts on tourism, now one of the fastest growing and largest sectors of the worldwide economy. Tourist business managers must implement evidence-based preparedness activities to enhance the survival potential and future profitability of their firms. Drawing upon recent research studies of the tourist industry during times of crisis and the broad social science knowledge base regarding human responses to disaster, seven key lessons are described. Emergency managers must facilitate the incorporation of these lessons into the culture of tourist business managers.

Graduate Education and Simulation Training for CBRNE Disasters Using a Multimodal Approach to Learning. Part 1: Education and Training from a Human-Performance Perspective

DTIC Science & Technology

2013-08-01

Learning Styles . Available at http://www2.umist.ac.uk.staff/talsc/TaLSC/VARK/default.htm; accessed Aug 9, 2010. 14. Joels M, Pu Z, Wiegert O, Oitzl M...and Simulation Training   for CBRNE Disasters Using a Multimodal  Approach to  Learning   Part 1: Education and Training from a Human‐ Performance...Graduate Education and Simulation Training for CBRNE Disasters Using a Multimodal 5a. CONTRACT NUMBER Approach to Learning . Part 1: Education and

Natural Disasters and Cholera Outbreaks: Current Understanding and Future Outlook.

PubMed

Jutla, Antarpreet; Khan, Rakibul; Colwell, Rita

2017-03-01

Diarrheal diseases remain a serious global public health threat, especially for those populations lacking access to safe water and sanitation infrastructure. Although association of several diarrheal diseases, e.g., cholera, shigellosis, etc., with climatic processes has been documented, the global human population remains at heightened risk of outbreak of diseases after natural disasters, such as earthquakes, floods, or droughts. In this review, cholera was selected as a signature diarrheal disease and the role of natural disasters in triggering and transmitting cholera was analyzed. Key observations include identification of an inherent feedback loop that includes societal structure, prevailing climatic processes, and spatio-temporal seasonal variability of natural disasters. Data obtained from satellite-based remote sensing are concluded to have application, although limited, in predicting risks of a cholera outbreak(s). We argue that with the advent of new high spectral and spatial resolution data, earth observation systems should be seamlessly integrated in a decision support mechanism to be mobilize resources when a region suffers a natural disaster. A framework is proposed that can be used to assess the impact of natural disasters with response to outbreak of cholera, providing assessment of short- and long-term influence of climatic processes on disease outbreaks.

Mental symptoms and cause-specific mortality among midlife employees.

PubMed

Lahelma, Eero; Pietiläinen, Olli; Rahkonen, Ossi; Lahti, Jouni; Lallukka, Tea

2016-11-08

Mental symptoms are prevalent among populations, but their associations with premature mortality are inadequately understood. We examined whether mental symptoms contribute to cause-specific mortality among midlife employees, while considering key covariates. Baseline mail survey data from 2000-02 included employees, aged 40-60, of the City of Helsinki, Finland (n = 8960, 80 % women, response rate 67 %). Mental symptoms were measured by the General Health Questionnaire 12-item version (GHQ-12) and the Short Form 36 mental component summary (MCS). Covariates included sex, marital status, social support, health behaviours, occupational social class and limiting long-standing illness. Causes of death by the end of 2013 were obtained from Statistics Finland (n = 242) and linked individually to survey data pending consent (n = 6605). Hazard ratios (HR) and 95 % confidence intervals (95 % CI) were calculated using Cox regression analysis. For all-cause mortality, only MCS showed a weak association before adjustments. For natural mortality, no associations were found. For unnatural mortality (n = 21), there was a sex adjusted association with GHQ (HR = 1.96, 95 % CI = 1.45-2.64) and MCS (2.30, 95 % CI = 1.72-3.08). Among unnatural causes of death suicidal mortality (n = 11) was associated with both GHQ (2.20, 95 % CI = 1.47-3.29) and MCS (2.68, 95 % CI = 1.80-3.99). Of the covariates limiting long-standing illness modestly attenuated the associations. Two established measures of mental symptoms, i.e. GHQ-12 and SF-36 MCS, were both associated with subsequent unnatural, i.e. accidental and violent, as well as suicidal mortality. No associations were found for natural mortality due to diseases. These findings need to be corroborated in further populations. Supporting mental health through workplace measures may help counteract subsequent suicidal and other unnatural mortality among midlife employees.

Death by Suicide in Graves' Disease and Graves' Orbitopathy: A Nationwide Danish Register Study.

PubMed

Ferløv-Schwensen, Charlotte; Brix, Thomas Heiberg; Hegedüs, Laszlo

2017-12-01

Graves' disease (GD) is associated with excess morbidity and mortality, but little is known about unnatural manners of death and the potential relation with Graves' orbitopathy (GO). This study investigated the risk of unnatural death in Graves' patients with and without orbitopathy compared to matched control populations. This was a cohort study covering all adult Danes (≥18 years) diagnosed with GD or GO during 1995-2012. Median follow-up time was 7.9 years (range 0-17.5 years). Utilizing the Danish Register of Causes of Death and the Danish National Patient Registry, 28,461 subjects with GD and 3965 with GO were identified and matched for age and sex with four subjects from the background population. The manner of death was identified, and hazard ratios (HR) for mortality due to unnatural deaths (accident, suicide, violence/homicide, and unknown) were calculated using Cox regression analyses, adjusted for pre-existing somatic and psychiatric morbidity. In Graves' disease overall (GD + GO), there was an increased risk of death from unknown unnatural manners (HR = 2.01 [confidence interval (CI) 1.17-3.45], p = 0.012) and of suicide, although the latter difference was not with certainty statistically significant (HR = 1.43 [CI 1.00-2.04], p = 0.053). There was no significant difference in risk of death from suicide in GD subjects compared to their controls (HR = 1.27 [CI 0.85-1.89], p = 0.253). However, GO patients had a significantly higher risk of death from suicide (HR = 2.71 [CI 1.16-6.32], p = 0.022). Mortality by suicide was increased in Graves' disease overall, most significantly in patients with GO, also after adjustment for pre-existing somatic and psychiatric disease. These findings indicate that GD and GO may have a significant role in the pathophysiological mechanisms of suicidal behavior. Beyond independent confirmation, reasons for this need to be explored in order to introduce preventive measures.

The role of groundwater governance in emergencies during different phases of natural disasters

NASA Astrophysics Data System (ADS)

Vrba, Jaroslav

2016-03-01

The establishment of water governance in emergency situations supports timely and effective reaction with regard to the risk and impact of natural disasters on drinking-water supplies and populations. Under such governance, emergency activities of governmental authorities, rescue and aid teams, water stakeholders, local communities and individuals are coordinated with the objective to prevent and/or mitigate disaster impact on water supplies, to reduce human suffering due to drinking-water failure during and in the post-disaster period, and to manage drinking-water services in emergency situations in an equitable manner. The availability of low-vulnerability groundwater resources that have been proven safe and protected by geological features, and with long residence time, can make water-related relief and rehabilitation activities during and after an emergency more rapid and effective. Such groundwater resources have to be included in water governance and their exploration must be coordinated with overall management of drinking-water services in emergencies. This paper discusses institutional and technical capacities needed for building effective groundwater governance policy and drinking-water risk and demand management in emergencies. Disaster-risk mitigation plans are described, along with relief measures and post-disaster rehabilitation and reconstruction activities, which support gradual renewal of drinking-water services on the level prior to the disaster. The role of groundwater governance in emergencies differs in individual phases of disaster (preparedness, warning, impact/relief, rehabilitation). Suggested activities and actions associated with these phases are summarized and analysed, and a mode of their implementation is proposed.

Real-time Forensic Disaster Analysis

NASA Astrophysics Data System (ADS)

Wenzel, F.; Daniell, J.; Khazai, B.; Mühr, B.; Kunz-Plapp, T.; Markus, M.; Vervaeck, A.

2012-04-01

The Center for Disaster Management and Risk Reduction Technology (CEDIM, www.cedim.de) - an interdisciplinary research center founded by the German Research Centre for Geoscience (GFZ) and Karlsruhe Institute of Technology (KIT) - has embarked on a new style of disaster research known as Forensic Disaster Analysis. The notion has been coined by the Integrated Research on Disaster Risk initiative (IRDR, www.irdrinternational.org) launched by ICSU in 2010. It has been defined as an approach to studying natural disasters that aims at uncovering the root causes of disasters through in-depth investigations that go beyond the reconnaissance reports and case studies typically conducted after disasters. In adopting this comprehensive understanding of disasters CEDIM adds a real-time component to the assessment and evaluation process. By comprehensive we mean that most if not all relevant aspects of disasters are considered and jointly analysed. This includes the impact (human, economy, and infrastructure), comparisons with recent historic events, social vulnerability, reconstruction and long-term impacts on livelihood issues. The forensic disaster analysis research mode is thus best characterized as "event-based research" through systematic investigation of critical issues arising after a disaster across various inter-related areas. The forensic approach requires (a) availability of global data bases regarding previous earthquake losses, socio-economic parameters, building stock information, etc.; (b) leveraging platforms such as the EERI clearing house, relief-web, and the many sources of local and international sources where information is organized; and (c) rapid access to critical information (e.g., crowd sourcing techniques) to improve our understanding of the complex dynamics of disasters. The main scientific questions being addressed are: What are critical factors that control loss of life, of infrastructure, and for economy? What are the critical interactions between hazard - socio-economic systems - technological systems? What were the protective measures and to what extent did they work? Can we predict pattern of losses and socio-economic implications for future extreme events from simple parameters: hazard parameters, historic evidence, socio-economic conditions? Can we predict implications for reconstruction from simple parameters: hazard parameters, historic evidence, socio-economic conditions? The M7.2 Van Earthquake (Eastern Turkey) of 23 Oct. 2011 serves as an example for a forensic approach.

Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology.

PubMed

Christophersen, Olav A; Haug, Anna

2011-01-20

Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g. between thromboxanes and prostacyclins) often leading to worsening of disease symptoms. Both the total rate of eicosanoid production and the balance between eicosanoids with opposite effects are strongly dependent on dietary factors, such as the daily intakes of various eicosanoid precursor fatty acids, and also on the intakes of several antioxidant nutrients including selenium and sulphur amino acids. Even though the underlying biochemical mechanisms have been thoroughly studied for more than 30 years, neither the agricultural sector nor medical practitioners have shown much interest in making practical use of the abundant high-quality research data now available. In this article, we discuss some specific examples of the interactions between diet and drugs in the pathogenesis and therapy of various common diseases. We also discuss, using common pain conditions and cancer as specific examples, how a better integration between agricultural science, nutrition and pharmacology could lead to improved treatment for important diseases (with improved overall therapeutic effect at the same time as negative side effects and therapy costs can be strongly reduced). It is shown how an unnaturally high omega-6/omega-3 fatty acid concentration ratio in meat, offal and eggs (because the omega-6/omega-3 ratio of the animal diet is unnaturally high) directly leads to exacerbation of pain conditions, cardiovascular disease and probably most cancers. It should be technologically easy and fairly inexpensive to produce poultry and pork meat with much more long-chain omega-3 fatty acids and less arachidonic acid than now, at the same time as they could also have a similar selenium concentration as is common in marine fish. The health economic benefits of such products for society as a whole must be expected vastly to outweigh the direct costs for the farming sector.

Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology

PubMed Central

2011-01-01

Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g. between thromboxanes and prostacyclins) often leading to worsening of disease symptoms. Both the total rate of eicosanoid production and the balance between eicosanoids with opposite effects are strongly dependent on dietary factors, such as the daily intakes of various eicosanoid precursor fatty acids, and also on the intakes of several antioxidant nutrients including selenium and sulphur amino acids. Even though the underlying biochemical mechanisms have been thoroughly studied for more than 30 years, neither the agricultural sector nor medical practitioners have shown much interest in making practical use of the abundant high-quality research data now available. In this article, we discuss some specific examples of the interactions between diet and drugs in the pathogenesis and therapy of various common diseases. We also discuss, using common pain conditions and cancer as specific examples, how a better integration between agricultural science, nutrition and pharmacology could lead to improved treatment for important diseases (with improved overall therapeutic effect at the same time as negative side effects and therapy costs can be strongly reduced). It is shown how an unnaturally high omega-6/omega-3 fatty acid concentration ratio in meat, offal and eggs (because the omega-6/omega-3 ratio of the animal diet is unnaturally high) directly leads to exacerbation of pain conditions, cardiovascular disease and probably most cancers. It should be technologically easy and fairly inexpensive to produce poultry and pork meat with much more long-chain omega-3 fatty acids and less arachidonic acid than now, at the same time as they could also have a similar selenium concentration as is common in marine fish. The health economic benefits of such products for society as a whole must be expected vastly to outweigh the direct costs for the farming sector. PMID:21247506

Integrating human behaviour dynamics into flood disaster risk assessment

NASA Astrophysics Data System (ADS)

Aerts, J. C. J. H.; Botzen, W. J.; Clarke, K. C.; Cutter, S. L.; Hall, J. W.; Merz, B.; Michel-Kerjan, E.; Mysiak, J.; Surminski, S.; Kunreuther, H.

2018-03-01

The behaviour of individuals, businesses, and government entities before, during, and immediately after a disaster can dramatically affect the impact and recovery time. However, existing risk-assessment methods rarely include this critical factor. In this Perspective, we show why this is a concern, and demonstrate that although initial efforts have inevitably represented human behaviour in limited terms, innovations in flood-risk assessment that integrate societal behaviour and behavioural adaptation dynamics into such quantifications may lead to more accurate characterization of risks and improved assessment of the effectiveness of risk-management strategies and investments. Such multidisciplinary approaches can inform flood-risk management policy development.

Development and Implementation of Real-Time Information Delivery Systems for Emergency Management

NASA Technical Reports Server (NTRS)

Wegener, Steve; Sullivan, Don; Ambrosia, Vince; Brass, James; Dann, R. Scott

2000-01-01

The disaster management community has an on-going need for real-time data and information, especially during catastrophic events. Currently, twin engine or jet aircraft with limited altitude and duration capabilities collect much of the data. Flight safety is also an issue. Clearly, much of the needed data could be delivered via over-the-horizon transfer through a uninhabited aerial vehicles (UAV) platform to mission managers at various locations on the ground. In fact, because of the ability to stay aloft for long periods of time, and to fly above dangerous situations, UAV's are ideally suited for disaster missions. There are numerous situations that can be considered disastrous for the human population. Some, such as fire or flood, can continue over a period of days. Disaster management officials rely on data from the site to respond in an optimum way with warnings, evacuations, rescue, relief, and to the extent possible, damage control. Although different types of disasters call for different types of response, most situations can be improved by having visual images and other remotely sensed data available. "Disaster Management" is actually made up of a number of activities, including: - Disaster Prevention and Mitigation - Emergency Response Planning - Disaster Management (real-time deployment of resources, during an event) - Disaster / Risk Modeling All of these activities could benefit from real-time information, but a major focus for UAV-based technology is in real-time deployment of resources (i.e., emergency response teams), based on changing conditions at the location of the event. With all these potential benefits, it is desirable to demonstrate to user agencies the ability to perform disaster management missions as described. The following demonstration project is the first in a program designed to prove the feasibility of supporting disaster missions with UAV technology and suitable communications packages on-board. A several-year program is envisioned, in which a broad range of disaster-related activities are demonstrated to the appropriate user communities.

Forensic Archaeological Recovery of a Large-Scale Mass Disaster Scene: Lessons Learned from Two Complex Recovery Operations at the World Trade Center Site.

PubMed

Warnasch, Scott C

2016-05-01

In 2006, unexpected discoveries of buried World Trade Center (WTC) debris and human remains were made at the World Trade Center mass disaster site. New York City's Office of Chief Medical Examiner (OCME) was given the task of systematically searching the site for any remaining victims' remains. The subsequent OCME assessment and archaeological excavation conducted from 2006 until 2013, resulted in the recovery of over 1,900 victims' remains. In addition, this operation demonstrated the essential skills archaeologists can provide in a mass disaster recovery operation. The OCME excavation data illustrates some of the challenges encountered during the original recovery effort of 2001/2002. It suggests that when understood within the larger site recovery context, certain fundamental components of the original recovery effort, such as operational priorities and activities in effect during the original recovery, directly or indirectly resulted in unsearched deposits that contained human remains. © 2016 American Academy of Forensic Sciences.

FIRE-CAT - An application for mobile devices for first response after natural disasters

NASA Astrophysics Data System (ADS)

Eggert, S.; Schmid, S.

2011-12-01

The FIRE-CAT application uses the technology of an easy to use mobile application that works independently from any phone system and applies it to the field of near real-time disaster management. The application allows the user to report about structural or human damages to the operation's head quarter. Requirements are a mobile phone or tablet based on the WebOS system and equipped with a GPS receiver. Starting the application, the user can tag a damage to the actual position he is. He can distinguish between different classes of damage, from "visually intact building" to "completely collapsed building" and add any further information concerning human losses or comments. This information will then be sent to a geographical information system in the head quarter. Information can also be updated, corrected or completed with comments. The damage map created by these reports from victims directly in the affected areas can then be a base for the disaster management to decide where to send rescue teams first.

Press freedom, oil exports, and risk for natural disasters: a challenge for climato-economic theory?

PubMed

Arantes, Joana; Grace, Randolph C; Kemp, Simon

2013-10-01

Does the interaction between climactic demands, monetary resources, and freedom suggest a more general relationship between the environmental challenges that human societies face and their resources to meet those challenges? Using data on press freedom (Van de Vliert 2011a), we found no evidence of a similar interaction with natural resources (as measured by oil exports) or risk for natural disasters.

Planning for partnerships: Maximizing surge capacity resources through service learning.

PubMed

Adams, Lavonne M; Reams, Paula K; Canclini, Sharon B

2015-01-01

Infectious disease outbreaks and natural or human-caused disasters can strain the community's surge capacity through sudden demand on healthcare activities. Collaborative partnerships between communities and schools of nursing have the potential to maximize resource availability to meet community needs following a disaster. This article explores how communities can work with schools of nursing to enhance surge capacity through systems thinking, integrated planning, and cooperative efforts.

Current genetic methodologies in the identification of disaster victims and in forensic analysis.

PubMed

Ziętkiewicz, Ewa; Witt, Magdalena; Daca, Patrycja; Zebracka-Gala, Jadwiga; Goniewicz, Mariusz; Jarząb, Barbara; Witt, Michał

2012-02-01

This review presents the basic problems and currently available molecular techniques used for genetic profiling in disaster victim identification (DVI). The environmental conditions of a mass disaster often result in severe fragmentation, decomposition and intermixing of the remains of victims. In such cases, traditional identification based on the anthropological and physical characteristics of the victims is frequently inconclusive. This is the reason why DNA profiling became the gold standard for victim identification in mass-casualty incidents (MCIs) or any forensic cases where human remains are highly fragmented and/or degraded beyond recognition. The review provides general information about the sources of genetic material for DNA profiling, the genetic markers routinely used during genetic profiling (STR markers, mtDNA and single-nucleotide polymorphisms [SNP]) and the basic statistical approaches used in DNA-based disaster victim identification. Automated technological platforms that allow the simultaneous analysis of a multitude of genetic markers used in genetic identification (oligonucleotide microarray techniques and next-generation sequencing) are also presented. Forensic and population databases containing information on human variability, routinely used for statistical analyses, are discussed. The final part of this review is focused on recent developments, which offer particularly promising tools for forensic applications (mRNA analysis, transcriptome variation in individuals/populations and genetic profiling of specific cells separated from mixtures).

Bayesian modeling to assess populated areas impacted by radiation from Fukushima

NASA Astrophysics Data System (ADS)

Hultquist, C.; Cervone, G.

2017-12-01

Citizen-led movements producing spatio-temporal big data are increasingly important sources of information about populations that are impacted by natural disasters. Citizen science can be used to fill gaps in disaster monitoring data, in addition to inferring human exposure and vulnerability to extreme environmental impacts. As a response to the 2011 release of radiation from Fukushima, Japan, the Safecast project began collecting open radiation data which grew to be a global dataset of over 70 million measurements to date. This dataset is spatially distributed primarily where humans are located and demonstrates abnormal patterns of population movements as a result of the disaster. Previous work has demonstrated that Safecast is highly correlated in comparison to government radiation observations. However, there is still a scientific need to understand the geostatistical variability of Safecast data and to assess how reliable the data are over space and time. The Bayesian hierarchical approach can be used to model the spatial distribution of datasets and flexibly integrate new flows of data without losing previous information. This enables an understanding of uncertainty in the spatio-temporal data to inform decision makers on areas of high levels of radiation where populations are located. Citizen science data can be scientifically evaluated and used as a critical source of information about populations that are impacted by a disaster.

Evaluation of Loss Due to Storm Surge Disasters in China Based on Econometric Model Groups.

PubMed

Jin, Xue; Shi, Xiaoxia; Gao, Jintian; Xu, Tongbin; Yin, Kedong

2018-03-27

Storm surge has become an important factor restricting the economic and social development of China's coastal regions. In order to improve the scientific judgment of future storm surge damage, a method of model groups is proposed to refine the evaluation of the loss due to storm surges. Due to the relative dispersion and poor regularity of the natural property data (login center air pressure, maximum wind speed, maximum storm water, super warning water level, etc.), storm surge disaster is divided based on eight kinds of storm surge disaster grade division methods combined with storm surge water, hypervigilance tide level, and disaster loss. The storm surge disaster loss measurement model groups consist of eight equations, and six major modules are constructed: storm surge disaster in agricultural loss, fishery loss, human resource loss, engineering facility loss, living facility loss, and direct economic loss. Finally, the support vector machine (SVM) model is used to evaluate the loss and the intra-sample prediction. It is indicated that the equations of the model groups can reflect in detail the relationship between the damage of storm surges and other related variables. Based on a comparison of the original value and the predicted value error, the model groups pass the test, providing scientific support and a decision basis for the early layout of disaster prevention and mitigation.

Challenges of Managing Animals in Disasters in the U.S.

PubMed Central

Heath, Sebastian E.; Linnabary, Robert D.

2015-01-01

Simple Summary This article describes common challenges to managing animals in disasters in the US, summarizes how some of these challenges are being met and makes recommendations on how to overcome others. Many predictable adverse situations affecting animals and their owners can be prevented when communities develop a comprehensive emergency management strategy that integrates animal care into planning, preparedness, mitigation, and recovery activities, as well as response. Abstract Common to many of the repeated issues surrounding animals in disasters in the U.S. is a pre-existing weak animal health infrastructure that is under constant pressure resulting from pet overpopulation. Unless this root cause is addressed, communities remain vulnerable to similar issues with animals they and others have faced in past disasters. In the US the plight of animals in disasters is frequently viewed primarily as a response issue and frequently handled by groups that are not integrated with the affected community’s emergency management. In contrast, animals, their owners, and communities would greatly benefit from integrating animal issues into an overall emergency management strategy for the community. There is no other factor contributing as much to human evacuation failure in disasters that is under the control of emergency management when a threat is imminent as pet ownership. Emergency managers can take advantage of the bond people have with their animals to instill appropriate behavior amongst pet owners in disasters. PMID:26479228

Evaluation of Loss Due to Storm Surge Disasters in China Based on Econometric Model Groups

PubMed Central

Shi, Xiaoxia; Xu, Tongbin; Yin, Kedong

2018-01-01

Storm surge has become an important factor restricting the economic and social development of China’s coastal regions. In order to improve the scientific judgment of future storm surge damage, a method of model groups is proposed to refine the evaluation of the loss due to storm surges. Due to the relative dispersion and poor regularity of the natural property data (login center air pressure, maximum wind speed, maximum storm water, super warning water level, etc.), storm surge disaster is divided based on eight kinds of storm surge disaster grade division methods combined with storm surge water, hypervigilance tide level, and disaster loss. The storm surge disaster loss measurement model groups consist of eight equations, and six major modules are constructed: storm surge disaster in agricultural loss, fishery loss, human resource loss, engineering facility loss, living facility loss, and direct economic loss. Finally, the support vector machine (SVM) model is used to evaluate the loss and the intra-sample prediction. It is indicated that the equations of the model groups can reflect in detail the relationship between the damage of storm surges and other related variables. Based on a comparison of the original value and the predicted value error, the model groups pass the test, providing scientific support and a decision basis for the early layout of disaster prevention and mitigation. PMID:29584628

Extreme Geohazards: Reducing the Disaster Risk and Increasing Resilience

NASA Astrophysics Data System (ADS)

Plag, Hans-Peter; Stein, Seth; Brocklebank, Sean; Jules-Plag, Shelley; Marsh, Stuart; Campus, Paola

2013-04-01

Extreme geohazards have the potential to escalate the global sustainability crisis and put us close to the boundaries of the safe operating space for humanity. Exposure of human assets to geohazards has increased dramatically in recent decades, and the sensitivity of the built environment and the embedded socio-economic fabric have changed. We are putting the urban environment, including megacities, in harm's way. Paradoxically, innovation during recent decades, in particular, urban innovation, has increased the disaster risk and coupled this risk to the sustainability crisis. Only more innovation can reduce disaster risk and lead us out of the sustainability crisis. Extreme geohazards (volcanic eruptions, earthquakes, tsunamis) that occurred regularly throughout the last few millennia mostly did not cause major disasters because population density was low and the built environment was not sprawling into hazardous areas to the same extent as today. Similar extreme events today would cause unparalleled damage on a global scale and could worsen the sustainability crisis. Simulation of these extreme hazards under present conditions can help to assess the disaster risk. The Geohazards Community of Practice of the Group on Earth Observations (GEO) with support from the European Science Foundation is preparing a white paper assessing the contemporary disaster risks associated with extreme geohazards and developing a vision for science and society to engage in deliberations addressing this risk (see http://www.geohazcop.org/projects/extgeowp). Risk awareness and monitoring is highly uneven across the world, and this creates two kinds of problems. Firstly, potential hazards are much more closely monitored in wealthy countries than in the developing world. But the largest hazards are global in nature, and it is critical to get as much forewarning as possible to develop an effective response. The disasters and near-misses of the past show that adherence to scientific knowledge, particularly during the early warning phase, can reduce disasters. This suggests that a strong global monitoring system for geohazards is needed, not least to support the early detection of extreme hazards. Secondly, low risk awareness combined with poverty, corruption, and a lack of building codes and informed land use management creates the conditions to turn hazards into disasters throughout much of the developing world. Democratizing knowledge about extreme geohazards is very important in order to inform deliberations of disaster risks and community strategies that can reduce the disaster risk by increasing resilience and adaptive capacities without compromising the livelihood of communities. We use a four-order scheme to define disaster risk outcomes and associated societal processes. This framework can be implemented in the context of deliberative democracy and governance with participation of the community. The current dialog between science and society is not fully capable of supporting deliberative governance and a democratizing of knowledge. Most scientific knowledge is created independent of those who could put it to use, and a transition to co-design and co-development of knowledge involving a broad stakeholder base is necessary to address the disaster risk associated with extreme events. This transition may have the consequence of more responsibility and even liability for science.

Evidence for unnatural-parity contributions to electron-impact ionization of laser-aligned atoms

DOE PAGES

Armstrong, Gregory S. J.; Colgan, James Patrick; Pindzola, M. S.; ...

2015-09-11

Recent measurements have examined the electron-impact ionization of excited-state laser-aligned Mg atoms. In this paper we show that the ionization cross section arising from the geometry where the aligned atom is perpendicular to the scattering plane directly probes the unnatural parity contributions to the ionization amplitude. The contributions from natural parity partial waves cancel exactly in this geometry. Our calculations resolve the discrepancy between the nonzero measured cross sections in this plane and the zero cross section predicted by distorted-wave approaches. Finally, we demonstrate that this is a general feature of ionization from p-state targets by additional studies of ionizationmore » from excited Ca and Na atoms.« less

Human rights and mass disaster: lessons from the 2004 tsunami.

PubMed

Weinstein, H M; Fletcher, L E; Stover, E

2007-01-01

This paper describes the results of an investigation into how the December, 2004 tsunami and its aftermath affected the human rights of the survivors. Teams of researchers interviewed survivors, government officials, representatives of international and local nongovernmental organisations, UN officials, the military, police, and other key informants in India, Sri Lanka, the Maldives, Indonesia, and Thailand. We also analysed newspaper articles, reports released by governments, UN agencies, NGOs, and private humanitarian aid groups, and we examined the laws and policies related to survivors' welfare in the affected countries. We found worsening of prior human rights violations, inequities in aid distribution, lack of accountability and impunity, poor coordination of aid, lack of community participation in reconstruction, including coastal redevelopment. Corruption and preexisting conflict negatively impact humanitarian interventions. We make recommendations to international agencies, states, and local health service providers. A human rights framework offers significant protection to survivors and should play a critical role in disaster response.

Information Dissemination Analysis of Different Media towards the Application for Disaster Pre-Warning

PubMed Central

Zhang, Nan; Huang, Hong; Su, Boni; Zhao, Jinlong; Zhang, Bo

2014-01-01

Knowing the information dissemination mechanisms of different media and having an efficient information dissemination plan for disaster pre-warning plays a very important role in reducing losses and ensuring the safety of human beings. In this paper we established models of information dissemination for six typical information media, including short message service (SMS), microblogs, news portals, cell phones, television, and oral communication. Then, the information dissemination capability of each medium concerning individuals of different ages, genders, and residential areas was simulated, and the dissemination characteristics were studied. Finally, radar graphs were used to illustrate comprehensive assessments of the six media; these graphs show directly the information dissemination characteristics of all media. The models and the results are essential for improving the efficiency of information dissemination for the purpose of disaster pre-warning and for formulating emergency plans which help to reduce the possibility of injuries, deaths and other losses in a disaster. PMID:24878739

Information dissemination analysis of different media towards the application for disaster pre-warning.

PubMed

Zhang, Nan; Huang, Hong; Su, Boni; Zhao, Jinlong; Zhang, Bo

2014-01-01

Knowing the information dissemination mechanisms of different media and having an efficient information dissemination plan for disaster pre-warning plays a very important role in reducing losses and ensuring the safety of human beings. In this paper we established models of information dissemination for six typical information media, including short message service (SMS), microblogs, news portals, cell phones, television, and oral communication. Then, the information dissemination capability of each medium concerning individuals of different ages, genders, and residential areas was simulated, and the dissemination characteristics were studied. Finally, radar graphs were used to illustrate comprehensive assessments of the six media; these graphs show directly the information dissemination characteristics of all media. The models and the results are essential for improving the efficiency of information dissemination for the purpose of disaster pre-warning and for formulating emergency plans which help to reduce the possibility of injuries, deaths and other losses in a disaster.

Ethical dilemmas related to predictions and warnings of impending natural disaster.

PubMed

Phua, Kai-Lit; Hue, J W

2013-01-01

Scientists and policy makers issuing predictions and warnings of impending natural disaster are faced with two major challenges, that is, failure to warn and issuing a false alarm. The consequences of failure to warn can be serious for society overall, for example, significant economic losses, heavy infrastructure and environmental damage, large number of human casualties, and social disruption. Failure to warn can also have serious for specific individuals, for example, legal proceedings against disaster research scientists, as in the L'Aquila earthquake affair. The consequences of false alarms may be less serious. Nevertheless, false alarms may violate the principle of nonmaleficence (do no harm), affect individual autonomy (eg, mandatory evacuations), and may result in the "cry wolf" effect. Other ethical issues associated with natural disasters include the promotion of global justice through international predisaster technical assistance and postdisaster aid. Social justice within a particular country is promoted through greater postdisaster aid allocation to the less privileged.

Bridging the sanitation gap between disaster relief and development.

PubMed

Lai, Ka-Man; Ramirez, Claudia; Liu, Weilong; Kirilova, Darina; Vick, David; Mari, Joe; Smith, Rachel; Lam, Ho-Yin; Ostovari, Afshin; Shibakawa, Akifumi; Liu, Yang; Samant, Sidharth; Osaro, Lucky

2015-10-01

By interpreting disasters as opportunities to initiate the fulfilment of development needs, realise the vulnerability of the affected community and environment, and extend the legacy of relief funds and effort, this paper builds upon the concept linking relief, rehabilitation and development (LRRD) in the sanitation sector. It aims to use a composite of case studies to devise a framework for a semi-hypothetical scenario to identify critical components and generic processes for a LRRD action plan. The scenario is based on a latrine wetland sanitation system in a Muslim community. Several sub-frameworks are developed: (i) latrine design; (ii) assessment of human waste treatment; (iii) connective sanitation promotion strategy; and (iv) ecological systems and environmental services for sanitation and development. This scenario illustrates the complex issues involved in LRRD in sanitation work and provides technical notes and references for a legacy plan for disaster relief and development. © 2015 The Author(s). Disasters © Overseas Development Institute, 2015.

Monitoring Disaster-Related Power Outages Using NASA Black Marble Nighttime Light Product

NASA Astrophysics Data System (ADS)

Wang, Z.; Román, M. O.; Sun, Q.; Molthan, A. L.; Schultz, L. A.; Kalb, V. L.

2018-04-01

Timely and accurate monitoring of disruptions to the electricity grid, including the magnitude, spatial extent, timing, and duration of net power losses, is needed to improve situational awareness of disaster response and long-term recovery efforts. Satellite-derived Nighttime Lights (NTL) provide an indication of human activity patterns and have been successfully used to monitor disaster-related power outages. The global 500 m spatial resolution National Aeronautics and Space Administration (NASA) Black Marble NTL daily standard product suite (VNP46) is generated from Visible Infrared Imaging Radiometer Suite (VIIRS) Day/Night Band (DNB) onboard the NASA/National Oceanic and Atmospheric Administration (NOAA) Suomi National Polar-orbiting Partnership (Suomi- NPP) satellite, which began operations on 19 January 2012. With its improvements in product accuracy (including critical atmospheric and BRDF correction routines), the VIIRS daily Black Mable product enables systematic monitoring of outage conditions across all stages of the disaster management cycle.

How to learn and develop from both good and bad lessons- the 2011Tohoku tsunami case -

NASA Astrophysics Data System (ADS)

Sugimoto, Megumi; Okazumi, Toshio

2013-04-01

The 2011 Tohoku tsunami revealed Japan has repeated same mistakes in a long tsunami disaster history. After the disaster Japanese remember many old lessons and materials: an oral traditional evacuation method 'Tsunami TENDENKO' which is individual independent quick evacuation, a tsunami historical memorial stone "Don't construct houses below this stone to seaside" in Aneyoshi town Iwate prefecture, Namiwake-shrine naming from the story of protect people from tsunami in Sendai city, and so on. Tohoku area has created various tsunami historical cultures to descendent. Tohoku area had not had a tsunami disaster for 50 years after the 1960 Chilean tsunami. The 2010 Chilean tsunami damaged little fish industry. People gradually lost tsunami disaster awareness. At just the bad time the magnitude (M) 9 scale earthquake attacked Tohoku. It was for our generations an inexperienced scale disaster. People did not make use of the ancestor's lessons to survive. The 2004 Sumatra tsunami attacked just before 7 years ago. The magnitude scale is almost same as M 9 scale. Why didn't Tohoku people and Japanese tsunami experts make use of the lessons? Japanese has a character outside Japan. This lesson shows it is difficult for human being to learn from other countries. As for Three mile island accident case in US, it was same for Japan. To addition to this, there are similar types of living lessons among different hazards. For examples, nuclear power plantations problem occurred both the 2012 Hurricane Sandy in US and the 2011 Tohoku tsunami. Both local people were not informed about the troubles though Oyster creek nuclear power station case in US did not proceed seriously all. Tsunami and Hurricane are different hazard. Each exparts stick to their last. 1. It is difficult for human being to transfer living lessons through next generation over decades. 2. It is difficult for human being to forecast inexperienced events. 3. It is usually underestimated the danger because human being have a tendency to judge based on own experience. 4. It is difficult for human being to make use of lessons from different countries because human being would not like to think own self suffer victim for a self-preservation mind. 5. It is usual for experts not to pay attention to other fields even if similar case occurs in different fields. We started collecting 18 hazards of such historical living lessons all over the world before the 2011 Tohoku tsunami. We adapted to this project collecting lessons from Tohoku tsunami and will publish for small children in developing countries in March 2013. This will be translated in at least 10 languages. This disaster lessons guide books are free. We will introduce some lessons in the presentations. We believe education is one of useful countermeasures to prevent from repeating same mistakes and transfer directly living lessons to new generations.

Assessing the economic impacts of drought from the perspective of profit loss rate: a case study of the sugar industry in China

NASA Astrophysics Data System (ADS)

Wang, Y.; Lin, L.; Chen, H.

2015-02-01

Natural disasters have enormous impacts on human society, especially on the development of the economy. To support decision making in mitigation and adaption to natural disasters, assessment of economic impacts is fundamental and of great significance. Based on a review of the literature of economic impact evaluation, this paper proposes a new assessment model of economic impact from drought by using the sugar industry in China as a case study, which focuses on the generation and transfer of economic impacts along a simple value chain involving only sugarcane growers and a sugar producing company. A perspective of profit loss rate is applied to scale economic impact with a model based on cost-and-benefit analysis. By using analysis of "with-and-without", profit loss is defined as the difference in profits between disaster-hit and disaster-free scenarios. To calculate profit, analysis on a time series of sugar price is applied. With the support of a linear regression model, an endogenous trend in sugar price is identified, and the time series of sugar price "without" disaster is obtained using an autoregressive error model to separate impact by disasters from the internal trend in sugar price. Unlike the settings in other assessment models, representative sugar prices, which represent value level in disaster-free condition and disaster-hit condition, are integrated from a long time series that covers the whole period of drought. As a result, it is found that in a rigid farming contract, sugarcane growers suffer far more than the sugar company when impacted by severe drought, which may promote the reflections on economic equality among various economic bodies at the occurrence of natural disasters.

International Charter `Space and Major Disasters' Collaborations

NASA Astrophysics Data System (ADS)

Jones, B. K.

2017-12-01

The International Charter aims at providing a unified system of space data acquisition and delivery to national disaster authorities of countries affected by natural or man-made disasters. Each of the sixteen Member Agencies has committed resources to support the objectives of the Charter and thus helping to mitigate the effects of disasters on human life and property, getting critical information into the hands of the disaster responders so that they can make informed decisions in the wake of a disaster. The Charter Member Agencies work together to provide remotely sensed imagery to any requesting country that is experiencing a natural or man-made disaster. The Space Agencies contribute priority satellite taskings, archive retrievals, and map production, as well as imagery of the affected areas. The imagery is provided at no cost to the affected country and is made available for the immediate response phase of the disaster. The Charter also has agreements with Sentinel Asia to submit activation requests on behalf of its 30+ member countries and the United Nations Office of Outer Space Affairs (UN OOSA) and United Nations Institute for Training and Research (UNITAR)/ United Nations Operational Satellite Applications Programme (UNOSAT) to submit activations on behalf of United Nations relief agencies such as UNICEF and UNOCHA. To further expand accessibility to the Charter Member Agency resources, the Charter has implemented the Universal Access initiative, which allows any country's disaster management authority to submit an application, attend a brief training session, and after successful completion, become an Authorized User able to submit activation requests without assistance from Member Agencies. The data provided by the Charter is used for many purposes including damage assessments, reference maps, evacuation route planning, search and rescue operations, decision maker briefings, scientific evaluations, and other response activities.

Low-Cost Rescue Robot for Disaster Management in a Developing Country: Development of a Prototype Using Locally Available Technology

NASA Technical Reports Server (NTRS)

Mahmud, Faisal; Hossain, S. G. M.; Bin, Jobair

2010-01-01

The use of robots in different fields is common and effective in developed countries. In case of incident management or emergency rescue after a disaster, robots are often used to lessen the human effort where it is either impossible or life-threatening for rescuers. Though developed countries can afford robotic-effort for pro-disaster management, the scenario is totally opposite for developing and under-developed countries to engage such a machine-help due to high cost of the machines and high maintenance cost as well. In this research paper, the authors proposed a low-cost "Rescue-Robot" for pro-disaster management which can overcome the budget-constraints as well as fully capable of rescue purposes for incident management. Here, all the research works were performed in Bangladesh - a developing country in South Asia. A disaster struck structure was chosen and a thorough survey was performed to understand the real-life environment for the prototype. The prototype was developed considering the results of this survey and it was manufactured using all locally available components and facilities.

Mexico City's Petroleos Mexicanos explosion: disaster management and air medical transport.

PubMed

Urquieta, Emmanuel; Varon, Joseph

2014-01-01

Mexico City is the largest metropolitan area in the Americas and 1 of the largest in the world; its geographic location and uncontrolled population and industrial growth make this metropolis prone to natural and human-made disasters. Mass casualty disaster responses in Mexico City tend to have complications from multiple logistical and operational challenges. This article focuses on the experiences and lessons learned from an explosion that occurred in a government building in Mexico City and the current status of mass casualty disaster risks and response strategies in Mexico City as well as air medical evacuation, which is a critical component and was shown to be extremely useful in the evacuation of 15 critically ill and polytraumatized patients (Injury Severity Score > 15). Several components of the public and privately owned emergency medical services and health care systems among Mexico City pose serious logistical and operational complications, which finally will be addressed by a joint emergency preparedness council to unify criteria in communications, triage, and incident/disaster command post establishment. Copyright © 2014 Air Medical Journal Associates. Published by Elsevier Inc. All rights reserved.

Dynamics of coupled human-landscape systems

NASA Astrophysics Data System (ADS)

Werner, B. T.; McNamara, D. E.

2007-11-01

A preliminary dynamical analysis of landscapes and humans as hierarchical complex systems suggests that strong coupling between the two that spreads to become regionally or globally pervasive should be focused at multi-year to decadal time scales. At these scales, landscape dynamics is dominated by water, sediment and biological routing mediated by fluvial, oceanic, atmospheric processes and human dynamics is dominated by simplifying, profit-maximizing market forces and political action based on projection of economic effect. Also at these scales, landscapes impact humans through patterns of natural disasters and trends such as sea level rise; humans impact landscapes by the effect of economic activity and changes meant to mitigate natural disasters and longer term trends. Based on this analysis, human-landscape coupled systems can be modeled using heterogeneous agents employing prediction models to determine actions to represent the nonlinear behavior of economic and political systems and rule-based routing algorithms to represent landscape processes. A cellular model for the development of New Orleans illustrates this approach, with routing algorithms for river and hurricane-storm surge determining flood extent, five markets (home, labor, hotel, tourism and port services) connecting seven types of economic agents (home buyers/laborers, home developers, hotel owners/ employers, hotel developers, tourists, port services developer and port services owners/employers), building of levees or a river spillway by political agents and damage to homes, hotels or port services within cells determined by the passage or depth of flood waters. The model reproduces historical aspects of New Orleans economic development and levee construction and the filtering of frequent small-scale floods at the expense of large disasters.

Children of War and Peace: A Human Development Perspective

ERIC Educational Resources Information Center

Sagi-Schwartz, Abraham

2012-01-01

Political conflicts and intractable wars can be conceived as disasters of human activities and they affect the entire life of children and their families. An ecological-transactional perspective of human development is adopted in order to identify multilevel developmental and contextual trajectories that might facilitate or impede the willingness…

Promoting Disaster Science and Disaster Science Communities as Part of Sound Disaster Preparedness

NASA Astrophysics Data System (ADS)

McNutt, M. K.

2015-12-01

During disasters, effectively engaging the vast expertise of the academic community can help responders make timely and critical decisions. A barrier to such engagement, however, is the cultural gap between reward systems in academia and in the disaster response community. Responders often are focused on ending the emergency quickly with minimal damage. Academic scientists often need to produce peer reviewed publications to justify their use of time and money. Each community is used to speaking to different audiences, and delivering answers on their own time scales. One approach to bridge this divide is to foster a cohesive community of interdisciplinary disaster scientists: researchers who focus on crises that severely and negatively disrupt the environment or threaten human health, and are able to apply scientific methods in a timely manner to understand how to prevent, mitigate, respond to, or recover from such events. Once organized, a disaster science community could develop its own unique culture. It is well known in the disaster response community that all the preparation that takes place before an event ever occurs is what truly makes the difference in reducing response time, improving coordination, and ultimately reducing impacts. In the same vein, disaster scientists would benefit from consistently interacting with the response community. The advantage of building a community for all disasters, rather than for just one type, is that it will help researchers maintain momentum between emergencies, which may be decades or more apart. Every disaster poses similar challenges: Knowing when to speak to the press and what to say; how to get rapid, actionable peer review; how to keep proprietary industry information confidential; how to develop "no regrets" actions; and how to communicate with decision makers and the public. During the Deepwater Horizonspill, I personally worked with members of the academic research community who cared not whether they got a peer reviewed publication out of their efforts: the spill was a crisis, and they felt it their duty to respond to the limits of their ability. And I worked with first responders who craved good scientific information for making decisions. By creating a community for disaster science, we might encourage and better reward such selfless service.

Georeferencing natural disaster impact footprints : lessons learned from the EM-DAT experience

NASA Astrophysics Data System (ADS)

Wallemacq, Pascaline; Guha Sapir, Debarati

2014-05-01

The Emergency Events Database (EM-DAT) contains data about the occurrence and consequences of all the disasters that have taken place since 1900. The main objectives of the database are to serve the purposes of humanitarian action at national and international levels; to aid decision making for disaster preparedness, as well as providing an objective base for vulnerability assessments and priority setting. EM-DAT records data on the human and economic impacts for each event as well as the location of said event. This is recorded as text data, namely the province, department, county, district, or village. The first purpose of geocoding (or georeferencing) the EM-DAT database is to transform the location data from text format into code data. The GAUL (Global Administrative Unit Layers) database (FAO) is used as a basis to identify the geographic footprint of the disaster, ideally to the second administrative level and add a unique code for each affected unit. Our first step has involved georeferencing earthquakes since the location of these is precise. The second purpose is to detail the degree of precision of georeferencing. The application and benefits of georeferencing are manifold. The geographic information of the footprint of past (after 2000) and future natural disasters permits the location of vulnerable areas with a GIS system and to cross data from different sources. It will allow the study of different elements such as the extent of a disaster and its human and economic consequences; the exposure and vulnerability of the population in space and time and the efficiency of mitigation measures. In addition, any association between events and external factors can be identified (e.g.: is the famine located at the same places as drought?) and precision of the information in the disaster report can be evaluated. Besides this, these maps will provide valuable communication support since maps have a high communication power and are easily understandable by the wider public and policy makers. Some results from the application of georeferencing will be presented during the session such as a study of the population potentially exposed and affected by natural disasters in Europe, a flood vulnerability analysis in Vietnam and the potential merging of watersheds analysis and flood footprints data.

El Salvador Armed Forces Procedures in Disaster Situations

DTIC Science & Technology

2008-03-25

in the Pacific Ocean. The channel of the Atlantic is composed by the ocean Atlantic, the Gulf of Mexico and the Caribbean Sea.1 For the present...Health and Social 6 Attendance, Ministry of Public Security, Foreign Ministry, Education Ministry, Ministry of Economy, and County Commission. In...activities, projects and programs that lead to the reduction of disaster risks that provoke human and economic losses caused by social and natural factors.18

Effective media communication of disasters: Pressing problems and recommendations

PubMed Central

Lowrey, Wilson; Evans, William; Gower, Karla K; Robinson, Jennifer A; Ginter, Peter M; McCormick, Lisa C; Abdolrasulnia, Maziar

2007-01-01

Background Public health officials and journalists play a crucial role in disseminating information regarding natural disasters, terrorism and other human-initiated disasters. However, research suggests that journalists are unprepared to cover terrorism and many types of natural disasters, in part because of lack sufficient expertise in science and medicine and training. The objective of this research was to identify solutions to problems facing journalists and public health public information officer (PIOs) of communicating with the public during natural and human-initiated disasters. Methods To assist in identifying the most pressing problems regarding media response to health-related risks such as terrorism and large-scale natural disasters, 26 expert advisors were convened, including leaders representing journalists and public information officers, state health officials, experts in terrorism and emergency preparedness, and experts in health, risk, and science communication. The advisory group participated in pre-arranged interviews and were asked to identify and review bioterrorism educational resources provided to journalist. All advisory group members were then invited to attend a day long meeting January 29, 2004 to review the findings and reach consensus. Results The most pressing problems were found to be a lack of coordination between PIO's and journalists, lack of resources for appropriately evaluating information and disseminating it efficiently, and a difference in perception of PIO's and journalist towards each others role during emergency situations. The advisory board developed a list of 15 recommendations that may enhance communication plans betweens PIO's, journalist and the public. The solutions were meant to be feasible in terms of costs and practical in terms of the professional and organizational realities in which journalists and PIO's work. Conclusion It is clear that PIO's and journalists play crucial roles in shaping public response to terrorism and other disasters. The findings from this formative research suggest that perspectives and organizational processes often limit effective communication between these groups; though practical solutions such as participation of journalists in drills, scenario exercises, sharing of informational resources, and raising awareness at professional trade meetings may enhance the timely dissemination of accurate and appropriate information. PMID:17553153

Geo-Spatial Social Network Analysis of Social Media to Mitigate Disasters

NASA Astrophysics Data System (ADS)

Carley, K. M.

2017-12-01

Understanding the spatial layout of human activity can afford a better understanding many phenomena - such as local cultural, the spread of ideas, and the scope of a disaster. Today, social media is one of the key sensors for acquiring information on socio-cultural activity, some with cues as to the geo-location. We ask, What can be learned by putting such data on maps? For example, are people who chat on line more likely to be near each other? Can Twitter data support disaster planning or early warning? In this talk, such issues are examined using data collected via Twitter and analyzed using ORA. ORA is a network analysis and visualization system. It supports not just social networks (who is interacting with whom), but also high dimensional networks with many types of nodes (e.g. people, organizations, resources, activities …) and relations, geo-spatial network analysis, dynamic network analysis, & geo-temporal analysis. Using ORA lessons learned from five case studies are considered: Arab Spring, Tsunami warning in Padang Indonesia, Twitter around Fukushima in Japan, Typhoon Haiyan (Yolanda), & regional conflict. Using Padang Indonesia data, we characterize the strengths and limitations of social media data to support disaster planning & early warning, identify at risk areas & issues of concern, and estimate where people are and which areas are impacted. Using Fukushima Japanese data, social media is used to estimate geo-spatial regularities in movement and communication that can inform disaster response and risk estimation. Using Arab Spring data, we find that the spread of bots & extremists varies by country and time, to the extent that using twitter to understand who is important or what ideas are critical can be compromised. Bots and extremists can exploit disaster messaging to create havoc and facilitate criminal activity e.g. human trafficking. Event discovery mechanisms support isolating geo-epi-centers for key events become crucial. Spatial inference enables improved country, and city identification. Geo-network analytics with and without these inferences reveal that explicitly geo-tagged data may not be representative and that improved location estimation provides better insight into the social condition. These results demonstrate the value of these technique to mitigate the social impact of disasters.

Building infrastructure to prevent disasters like Hurricane Maria

NASA Astrophysics Data System (ADS)

Bandaragoda, C.; Phuong, J.; Mooney, S.; Stephens, K.; Istanbulluoglu, E.; Pieper, K.; Rhoads, W.; Edwards, M.; Pruden, A.; Bales, J.; Clark, E.; Brazil, L.; Leon, M.; McDowell, W. G.; Horsburgh, J. S.; Tarboton, D. G.; Jones, A. S.; Hutton, E.; Tucker, G. E.; McCready, L.; Peckham, S. D.; Lenhardt, W. C.; Idaszak, R.

2017-12-01

2000 words Recovery efforts from natural disasters can be more efficient with data-driven information on current needs and future risks. We aim to advance open-source software infrastructure to support scientific investigation and data-driven decision making with a prototype system using a water quality assessment developed to investigate post-Hurricane Maria drinking water contamination in Puerto Rico. The widespread disruption of water treatment processes and uncertain drinking water quality within distribution systems in Puerto Rico poses risk to human health. However, there is no existing digital infrastructure to scientifically determine the impacts of the hurricane. After every natural disaster, it is difficult to answer elementary questions on how to provide high quality water supplies and health services. This project will archive and make accessible data on environmental variables unique to Puerto Rico, damage caused by Hurricane Maria, and will begin to address time sensitive needs of citizens. The initial focus is to work directly with public utilities to collect and archive samples of biological and inorganic drinking water quality. Our goal is to advance understanding of how the severity of a hazard to human health (e.g., no access to safe culinary water) is related to the sophistication, connectivity, and operations of the physical and related digital infrastructure systems. By rapidly collecting data in the early stages of recovery, we will test the design of an integrated cyberinfrastructure system to for usability of environmental and health data to understand the impacts from natural disasters. We will test and stress the CUAHSI HydroShare data publication mechanisms and capabilities to (1) assess the spatial and temporal presence of waterborne pathogens in public water systems impacted by a natural disaster, (2) demonstrate usability of HydroShare as a clearinghouse to centralize selected datasets related to Hurricane Maria, and (3) develop a prototype cyberinfrastructure to assess environmental conditions and public health impacted by natural disasters. The project thus serves to not only document post-disaster conditions, but develops a process to track the impact of recovery over time, as monitored through health, power availability and water quality.

No Pet or Their Person Left Behind: Increasing the Disaster Resilience of Vulnerable Groups through Animal Attachment, Activities and Networks

PubMed Central

Thompson, Kirrilly; Every, Danielle; Rainbird, Sophia; Cornell, Victoria; Smith, Bradley; Trigg, Joshua

2014-01-01

Simple Summary The potential for reconfiguring pet ownership from a risk factor to a protective factor for natural disaster survival has been recently proposed. But how might this resilience-building proposition apply to members of the community who are already considered vulnerable? This article addresses this important question by synthesizing information about what makes seven particular groups vulnerable, the challenges to increasing their resilience and how animals figure in their lives. It concludes that animal attachment could provide a novel conduit for accessing, communicating with and motivating vulnerable people to engage in resilience building behaviors that promote survival and facilitate recovery. Abstract Increased vulnerability to natural disasters has been associated with particular groups in the community. This includes those who are considered de facto vulnerable (children, older people, those with disabilities etc.) and those who own pets (not to mention pets themselves). The potential for reconfiguring pet ownership from a risk factor to a protective factor for natural disaster survival has been recently proposed. But how might this resilience-building proposition apply to vulnerable members of the community who own pets or other animals? This article addresses this important question by synthesizing information about what makes particular groups vulnerable, the challenges to increasing their resilience and how animals figure in their lives. Despite different vulnerabilities, animals were found to be important to the disaster resilience of seven vulnerable groups in Australia. Animal attachment and animal-related activities and networks are identified as underexplored devices for disseminating or ‘piggybacking’ disaster-related information and engaging vulnerable people in resilience building behaviors (in addition to including animals in disaster planning initiatives in general). Animals may provide the kind of innovative approach required to overcome the challenges in accessing and engaging vulnerable groups. As the survival of humans and animals are so often intertwined, the benefits of increasing the resilience of vulnerable communities through animal attachment is twofold: human and animal lives can be saved together. PMID:26480038

Effective media communication of disasters: pressing problems and recommendations.

PubMed

Lowrey, Wilson; Evans, William; Gower, Karla K; Robinson, Jennifer A; Ginter, Peter M; McCormick, Lisa C; Abdolrasulnia, Maziar

2007-06-06

Public health officials and journalists play a crucial role in disseminating information regarding natural disasters, terrorism and other human-initiated disasters. However, research suggests that journalists are unprepared to cover terrorism and many types of natural disasters, in part because of lack sufficient expertise in science and medicine and training. The objective of this research was to identify solutions to problems facing journalists and public health public information officer (PIOs) of communicating with the public during natural and human-initiated disasters. To assist in identifying the most pressing problems regarding media response to health-related risks such as terrorism and large-scale natural disasters, 26 expert advisors were convened, including leaders representing journalists and public information officers, state health officials, experts in terrorism and emergency preparedness, and experts in health, risk, and science communication. The advisory group participated in pre-arranged interviews and were asked to identify and review bioterrorism educational resources provided to journalist. All advisory group members were then invited to attend a day long meeting January 29, 2004 to review the findings and reach consensus. The most pressing problems were found to be a lack of coordination between PIO's and journalists, lack of resources for appropriately evaluating information and disseminating it efficiently, and a difference in perception of PIO's and journalist towards each others role during emergency situations. The advisory board developed a list of 15 recommendations that may enhance communication plans between PIO's, journalist and the public. The solutions were meant to be feasible in terms of costs and practical in terms of the professional and organizational realities in which journalists and PIO's work. It is clear that PIO's and journalists play crucial roles in shaping public response to terrorism and other disasters. The findings from this formative research suggest that perspectives and organizational processes often limit effective communication between these groups; though practical solutions such as participation of journalists in drills, scenario exercises, sharing of informational resources, and raising awareness at professional trade meetings may enhance the timely dissemination of accurate and appropriate information.

Geophysical Hazards and Preventive Disaster Management of Extreme Natural Events

NASA Astrophysics Data System (ADS)

Ismail-Zadeh, A.; Takeuchi, K.

2007-12-01

Geophysical hazard is potentially damaging natural event and/or phenomenon, which may cause the loss of life or injury, property damage, social and economic disruption, or environmental degradation. Extreme natural hazards are a key manifestation of the complex hierarchical nonlinear Earth system. An understanding, accurate modeling and forecasting of the extreme hazards are most important scientific challenges. Several recent extreme natural events (e.g., 2004 Great Indian Ocean Earthquake and Tsunami and the 2005 violent Katrina hurricane) demonstrated strong coupling between solid Earth and ocean, and ocean and atmosphere. These events resulted in great humanitarian tragedies because of a weak preventive disaster management. The less often natural events occur (and the extreme events are rare by definition), the more often the disaster managers postpone the preparedness to the events. The tendency to reduce the funding for preventive disaster management of natural catastrophes is seldom follows the rules of responsible stewardship for future generations neither in developing countries nor in highly developed economies where it must be considered next to malfeasance. Protecting human life and property against earthquake disasters requires an uninterrupted chain of tasks: from (i) understanding of physics of the events, analysis and monitoring, through (ii) interpretation, modeling, hazard assessment, and prediction, to (iii) public awareness, preparedness, and preventive disaster management.

Environmental hazards and psychopathology: Linking natural disasters with mental health

NASA Astrophysics Data System (ADS)

Perry, Ronald W.

1983-11-01

For some years, social scientists have been unable to agree on the extent to which experiencing a natural disaster is related to the presence of psychopathological symptoms Indeed, social scientists appear to be well-polarized, some arguing that disasters cause severe negative psychological reactions in victims, with others claiming that any psychological effects, if they exist at all, are minor and transient This paper reviews the controversy and identifies numerous conceptual and methodological difficulties associated with the competing positions. It is argued that the preoccupation of researchers with documenting positive or negative instances of psychological effects has lead them to ignore the issue of identifying processes through which disasters might impinge upon an individual's emotional stability. As a first step toward sketching out these processes, an extensive review of the literature on human response to natural disasters is undertaken. Eleven variables—level of community preparedness, scope of impact, duration of impact, destruction of kin and friendship networks, property damage, pre-impact psychological stability, social support, grief reactions, availability of institutional help, and successful coping skills—are identified as important in determining the psychological impact of disasters. These variables are operationalized and arranged into an interpretative framework that postulates the nature and magnitude of the interrelationships among them based upon the existing research literature

Gender, social norms, and survival in maritime disasters

PubMed Central

Elinder, Mikael; Erixson, Oscar

2012-01-01

Since the sinking of the Titanic, there has been a widespread belief that the social norm of “women and children first” (WCF) gives women a survival advantage over men in maritime disasters, and that captains and crew members give priority to passengers. We analyze a database of 18 maritime disasters spanning three centuries, covering the fate of over 15,000 individuals of more than 30 nationalities. Our results provide a unique picture of maritime disasters. Women have a distinct survival disadvantage compared with men. Captains and crew survive at a significantly higher rate than passengers. We also find that: the captain has the power to enforce normative behavior; there seems to be no association between duration of a disaster and the impact of social norms; women fare no better when they constitute a small share of the ship’s complement; the length of the voyage before the disaster appears to have no impact on women’s relative survival rate; the sex gap in survival rates has declined since World War I; and women have a larger disadvantage in British shipwrecks. Taken together, our findings show that human behavior in life-and-death situations is best captured by the expression “every man for himself.” PMID:22847426

Site-selective post-translational modification of proteins using an unnatural amino acid, 3-azidotyrosine.

PubMed

Ohno, Satoshi; Matsui, Megumi; Yokogawa, Takashi; Nakamura, Masashi; Hosoya, Takamitsu; Hiramatsu, Toshiyuki; Suzuki, Masaaki; Hayashi, Nobuhiro; Nishikawa, Kazuya

2007-03-01

An efficient method for site-selective modification of proteins using an unnatural amino acid, 3-azidotyrosine has been developed. This method utilizes the yeast amber suppressor tRNA(Tyr)/mutated tyrosyl-tRNA synthetase pair as a carrier of 3-azidotyrosine in an Escherichia coli cell-free translation system, and triarylphosphine derivatives for specific modification of the azido group. Using rat calmodulin (CaM) as a model protein, we prepared several unnatural CaM molecules, each carrying an azidotyrosine at predetermined positions 72, 78, 80 or 100, respectively. Post-translational modification of these proteins with a conjugate compound of triarylphosphine and biotin produced site-selectively biotinylated CaM molecules. Reaction efficiency was similar among these proteins irrespective of the position of introduction, and site-specificity of biotinylation was confirmed using mass spectrometry. In addition, CBP-binding activity of the biotinylated CaMs was confirmed to be similar to that of wild-type CaM. This method is intrinsically versatile in that it should be easily applicable to introducing any other desirable compounds (e.g., probes and cross-linkers) into selected sites of proteins as far as appropriate derivative compounds of triarylphosphine could be chemically synthesized. Elucidation of molecular mechanisms of protein functions and protein-to-protein networks will be greatly facilitated by making use of these site-selectively modified proteins.

Distributed Drug Discovery, Part 2: Global Rehearsal of Alkylating Agents for the Synthesis of Resin-Bound Unnatural Amino Acids and Virtual D3 Catalog Construction

PubMed Central

2008-01-01

Distributed Drug Discovery (D3) proposes solving large drug discovery problems by breaking them into smaller units for processing at multiple sites. A key component of the synthetic and computational stages of D3 is the global rehearsal of prospective reagents and their subsequent use in the creation of virtual catalogs of molecules accessible by simple, inexpensive combinatorial chemistry. The first section of this article documents the feasibility of the synthetic component of Distributed Drug Discovery. Twenty-four alkylating agents were rehearsed in the United States, Poland, Russia, and Spain, for their utility in the synthesis of resin-bound unnatural amino acids 1, key intermediates in many combinatorial chemistry procedures. This global reagent rehearsal, coupled to virtual library generation, increases the likelihood that any member of that virtual library can be made. It facilitates the realistic integration of worldwide virtual D3 catalog computational analysis with synthesis. The second part of this article describes the creation of the first virtual D3 catalog. It reports the enumeration of 24 416 acylated unnatural amino acids 5, assembled from lists of either rehearsed or well-precedented alkylating and acylating reagents, and describes how the resulting catalog can be freely accessed, searched, and downloaded by the scientific community. PMID:19105725

Current Technologies and its Trends of Machine Vision in the Field of Security and Disaster Prevention

NASA Astrophysics Data System (ADS)

Hashimoto, Manabu; Fujino, Yozo

Image sensing technologies are expected as useful and effective way to suppress damages by criminals and disasters in highly safe and relieved society. In this paper, we describe current important subjects, required functions, technical trends, and a couple of real examples of developed system. As for the video surveillance, recognition of human trajectory and human behavior using image processing techniques are introduced with real examples about the violence detection for elevators. In the field of facility monitoring technologies as civil engineering, useful machine vision applications such as automatic detection of concrete cracks on walls of a building or recognition of crowded people on bridge for effective guidance in emergency are shown.

Disaster Management in Flash Floods in Leh (Ladakh): A Case Study

PubMed Central

Gupta, Preeti; Khanna, Anurag; Majumdar, S

2012-01-01

Background: On August 6, 2010, in the dark of the midnight, there were flash floods due to cloud burst in Leh in Ladakh region of North India. It rained 14 inches in 2 hours, causing loss of human life and destruction. The civil hospital of Leh was badly damaged and rendered dysfunctional. Search and rescue operations were launched by the Indian Army immediately after the disaster. The injured and the dead were shifted to Army Hospital, Leh, and mass casualty management was started by the army doctors while relief work was mounted by the army and civil administration. Objective: The present study was done to document disaster management strategies and approaches and to assesses the impact of flash floods on human lives, health hazards, and future implications of a natural disaster. Materials and Methods: The approach used was both quantitative as well as qualitative. It included data collection from the primary sources of the district collectorate, interviews with the district civil administration, health officials, and army officials who organized rescue operations, restoration of communication and transport, mass casualty management, and informal discussions with local residents. Results: 234 persons died and over 800 were reported missing. Almost half of the people who died were local residents (49.6%) and foreigners (10.2%). Age-wise analysis of the deaths shows that the majority of deaths were reported in the age group of 25–50 years, accounting for 44.4% of deaths, followed by the 11–25-year age group with 22.2% deaths. The gender analysis showed that 61.5% were males and 38.5% were females. A further analysis showed that more females died in the age groups <10 years and ≥50 years. Conclusions: Disaster preparedness is critical, particularly in natural disasters. The Army's immediate search, rescue, and relief operations and mass casualty management effectively and efficiently mitigated the impact of flash floods, and restored normal life. PMID:23112446

Field Learning as a powerful tool of Education for geoscience, environment and disaster prevention.

NASA Astrophysics Data System (ADS)

Matsumoto, I.; LI, W.

2015-12-01

Field learning in through elementary school to University is very important for cultivation of science, environment and disaster prevention literacy. In Japan, we have various natural disasters such as earthquakes and volcanoes based on its geological settings ( Island-arc with subduction zone settings). And, it is a challenge environmental problem such as global warming prevention and energy problem to be solved by a human. For the above problem solving, it said that science education plays very important role. Especially learning with direct experience in the field is not only to get the only knowledge, we believe that greater development of science literacy, environmental literacy and disaster prevention literacy. In this presentation, we propose the new teaching method of field learning not only provided by school but also provided by outside school. We show following four studies that are (1) function of running water and origin of the land (science education and disaster prevention), (2) environmental consciousness of student (environmental education), (3) radiation education (scientific technology and its utilization) and (4) astronomical observation (acquisition of time and space concept). We were led to the preliminary conclusion of above four categories in practice research in and out of school. That is, the teacher is teaching the essence and phenomena of science to focus on science learning of school, in addition to environmental awareness, disaster prevention awareness, use of scientific technology are also important to teach at the same time. To do this, it is to make effective use of field learning. It can be said that the field study is a perfect and power place to perform learning such simultaneity. Because, natural field is originally the place can learn along with the feeling through the five senses of human. It is important especially for the growth stage of the student.

An engineering approach to miogravity syndrome.

PubMed

Sieving, D L

1997-04-01

The human species is rapidly expanding. Barring global catastrophe and unnatural constraints, it will, in a brief time on the scale of natural history, fill the uttermost reaches of the solar system. The beachhead established by President Kennedy's lunar program will lead to lunar, Martian and free space settlements in the next century. In a single generation of those who call them home, the constant 9.81 m.s-2 pull of Earth's gravity, which has influenced the evolution and development of terrestrial life forms for billions of years, will fade from common experience. Miogravity syndrome, a prognosticated complex arising in reduced gravity environments such as the surfaces of the Moon and Mars and principally encompassing muscle atrophy, cardiovascular deconditioning and bone demineralization, stands to replace physics and rocketry as the fundamental challenge of interplanetary astronautics. Mirroring our past few million years of changing climate and resources, the mobility of humans between diverse gravitational environments on the high frontier will critically depend on our ability to adapt. Tomorrow, as ever, a mushrooming penchant for toolmaking will spearhead the human career.

A personal philosophy of a radiation oncologist.

PubMed

Suit, Herman

2011-07-01

All humans are of one species and are near identical genetically, viz. >99.5%. Also note, the Chimp is >96% genetically identical to humans. There has been extremely rapid increase in information and knowledge and this is accelerating. Several points: time is absolutely equalitarian. There is and has not been an unnatural event in this universe. Luck is the dominant factor in an individual's success in life. At birth, the infant has zero choice of genes, parents, siblings, relatives, era and site of birth. In addition, the young child has essentially no choice in school [if any], health, etc. The key to advancing knowledge is asking decisive questions, proceeding to investigate and generate answers to the question posed and publishing the investigation, data and interpretation. The number 1 interest and concern of the physician is the care of the individual patient. The potential of "humanized experimental animals" for selected Phase III clinical trial within 2-3 decades is judged feasible. Physicians should view our current best treatment as obsolete and use this as a provocation for active effort to develop superior management strategies. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Tornado disasters and stress responses.

PubMed

Godleski, L S

1997-04-01

Each year, a number of tornados rip through Kentucky, leaving fear, destruction, and human injury in their path. Persons who endure these catastrophes often experience a variety of stress responses. The psychological and medical sequelae include depression, acute and post-traumatic stress disorders, substance abuse, anxiety, and somatization. It is especially important for the Kentucky practitioner to be able to recognize and screen for pathology following a tornado disaster in order to provide leadership in ascertaining treatment for such stress responses.

Dynamic Resource Allocation in Disaster Response: Tradeoffs in Wildfire Suppression

DTIC Science & Technology

2012-04-13

S, Martı́nez-Falero E, Pérez-González JM (2002) Optimiza- tion of the resources management in fighting wildfires . Environmental Management 30: 352...Dynamic Resource Allocation in Disaster Response: Tradeoffs in Wildfire Suppression Nada Petrovic1*, David L. Alderson2, Jean M. Carlson3 1Center for...inspire fundamentally new theoretical questions for dynamic decision making in coupled human and natural systems. Wildfires are one of several types of

Denial of flood aid to members of the Ahmadiyya Muslim community in Pakistan.

PubMed

Malik, Atif M

2011-07-14

During the catastrophic floods of 2010 in Pakistan, approximately 500 internally displaced families belonging to the Ahmadiyya sect of Islam were denied humanitarian relief. The failure of international agencies and Pakistan's government to protect basic human rights in the context of disaster relief raises profound questions. If all humanitarian work associated with natural disasters must be governed by canons of human rights, how should international agencies deal with legally empowered official discrimination? A review of the history of the Ahmadiyya community in Pakistan reveals decades of state-sanctioned persecution, particularly through its anti-blasphemy laws, and poses a serious challenge to the international community. When effective intervention is predicated on cooperation with state institutions, how can international relief agencies avoid becoming implicated in official discrimination? The denial of flood aid to Pakistan's Ahmadiyya community highlights the need for concerted action in disaster settings to prevent discrimination against vulnerable groups. Discriminatory legislation is not only a violation of basic norms enshrined in international compacts, it is a key problem for disaster relief. Copyright © 2011 Malik. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

Two hot to handle: How do we manage the simultaneous impacts of climate change and natural disasters on human health?

NASA Astrophysics Data System (ADS)

Phalkey, R. K.; Louis, V. R.

2016-05-01

Climate change is one of the major challenges we face today. There is recognition alongside evidence that the health impacts of both climate change and natural disasters are significant and rising. The impacts of both are also complex and span well beyond health to include environmental, social, demographic, cultural, and economic aspects of human lives. Nonetheless integrated impact assessments are rare and so are system level approaches or systematic preparedness and adaptation strategies to brace the two simultaneously particularly in low and middle-income countries. Ironically the impacts of both climate change as well as natural disasters will be disproportionately borne by low emitters. Sufficiently large and long-term data from comprehensive weather, socio-economic, demographic and health observational systems are currently unavailable to guide adaptation strategies with the necessary precision. In the absence of these and given the uncertainties around the health impact projections alongside the geographic disparities even within the countries, the main question is how can countries then prepare to brace the unknown? We certainly cannot wait to obtain answers to all the questions before we plan solutions. Strengthening health systems is therefore a pragmatic "zero regrets" strategy and should be adopted hastily before the parallel impacts from climate change and associated extreme weather events (disasters thereof) become too hot to handle.

A history of biological disasters of animal origin in North America.

PubMed

Ackerman, G A; Giroux, J

2006-04-01

This paper examines past occurrences in North America relevant to the possibility of biological disasters with animal origins. With respect to naturally occurring animal disease outbreaks, North America, while not as adversely affected by epizootics as other regions, has had its fair share of such outbreaks of both 'traditional' and emerging animal diseases. The traditional category includes such diseases as anthrax, classical swine fever, bluetongue, brucellosis, foot and mouth disease, and the family of equine encephalomyelitis viruses. The emerging diseases include relatively more recent culprits such as postweaning multisystemic wasting syndrome, poultry enteritis mortality syndrome, and newly discovered examples of the transmissible spongiform encephalopathies. Additionally, several serious diseases of human beings that involve animal vectors or reservoirs occur naturally in North America or have emerged in recent decades; these include plague, hantavirus, monkeypox, West Nile virus and avian-derived influenza. At the same time, there have been very few intentional attacks on livestock using biological agents and no recorded cases in North America of animals intentionally being used to transmit disease to humans. According to the historical record, therefore, naturally occurring emerging zoonoses probably constitute the greatest threat in terms of biological disasters with animal origins. However, some of the general trends in terrorist activity, such as the intensification of activities by animal rights extremists against facilities undertaking animal research, mean that the possibility of intentional animal-related biological disasters should not be discounted.

Study Of The Risks Arising From Natural Disasters And Hazards On Urban And Intercity Motorways By Using Failure Mode Effect Analysis (FMEA) Methods

NASA Astrophysics Data System (ADS)

DELİCE, Yavuz

2015-04-01

Highways, Located in the city and intercity locations are generally prone to many kind of natural disaster risks. Natural hazards and disasters that may occur firstly from highway project making to construction and operation stages and later during the implementation of highway maintenance and repair stages have to be taken into consideration. And assessment of risks that may occur against adverse situations is very important in terms of project design, construction, operation maintenance and repair costs. Making hazard and natural disaster risk analysis is largely depending on the definition of the likelihood of the probable hazards on the highways. However, assets at risk , and the impacts of the events must be examined and to be rated in their own. With the realization of these activities, intended improvements against natural hazards and disasters will be made with the utilization of Failure Mode Effects Analysis (FMEA) method and their effects will be analyzed with further works. FMEA, is a useful method to identify the failure mode and effects depending on the type of failure rate effects priorities and finding the most optimum economic and effective solution. Although relevant measures being taken for the identified risks by this analysis method , it may also provide some information for some public institutions about the nature of these risks when required. Thus, the necessary measures will have been taken in advance in the city and intercity highways. Many hazards and natural disasters are taken into account in risk assessments. The most important of these dangers can be listed as follows; • Natural disasters 1. Meteorological based natural disasters (floods, severe storms, tropical storms, winter storms, avalanches, etc.). 2. Geological based natural disasters (earthquakes, tsunamis, landslides, subsidence, sinkholes, etc) • Human originated disasters 1. Transport accidents (traffic accidents), originating from the road surface defects (icing, signaling caused malfunctions and risks), fire or explosion etc.- In this study, with FMEA method, risk analysis of the urban and intercity motorways against natural disasters and hazards have been performed and found solutions were brought against these risks. Keywords: Failure Modes Effects Analysis (FMEA), Pareto Analyses (PA), Highways, Risk Management.

Africa's Famine: The Human Dimension.

ERIC Educational Resources Information Center

Raloff, Janet

1985-01-01

Human activities are believed to have had major impact on disasters which have previously been called "natural." Overcultivation, overgrazing, and deforestation are used to illustrate how many African nations have become weakened and impoverished. Programs directed toward economic development are essential for overcoming these problems.…

An emergency medical communications system by low altitude platform at the early stages of a natural disaster in Indonesia.

PubMed

Qiantori, Andri; Sutiono, Agung Budi; Hariyanto, Hadi; Suwa, Hirohiko; Ohta, Toshizumi

2012-02-01

A natural disaster is a consequence of a natural hazard, such as a tsunami, earthquake or volcanic eruption, affecting humans. In order to support emergency medical communication services in natural disaster areas where the telecommunications facility has been seriously damaged, an ad hoc communication network backbone should be build to support emergency medical services. Combinations of requirements need to be considered before deciding on the best option. In the present study we have proposed a Low Altitude Platform consisting of tethered balloons combined with Wireless Fidelity (WiFi) 802.11 technology. To confirm that the suggested network would satisfy the emergency medical service requirements, a communications experiment, including performance service measurement, was carried out.

Natural Hazards, Second Edition

NASA Astrophysics Data System (ADS)

Rouhban, Badaoui

Natural disaster loss is on the rise, and the vulnerability of the human and physical environment to the violent forces of nature is increasing. In many parts of the world, disasters caused by natural hazards such as earthquakes, floods, landslides, drought, wildfires, intense windstorms, tsunami, and volcanic eruptions have caused the loss of human lives, injury, homelessness, and the destruction of economic and social infrastructure. Over the last few years, there has been an increase in the occurrence, severity, and intensity of disasters, culminating with the devastating tsunami of 26 December 2004 in South East Asia.Natural hazards are often unexpected or uncontrollable natural events of varying magnitude. Understanding their mechanisms and assessing their distribution in time and space are necessary for refining risk mitigation measures. This second edition of Natural Hazards, (following a first edition published in 1991 by Cambridge University Press), written by Edward Bryant, associate dean of science at Wollongong University, Australia, grapples with this crucial issue, aspects of hazard prediction, and other issues. The book presents a comprehensive analysis of different categories of hazards of climatic and geological origin.

A Qualitative Study of Violence Against Women after the Recent Disasters of Iran.

PubMed

Sohrabizadeh, Sanaz

2016-08-01

Introduction Violence against women (VAW) is one of the most widespread violations of human rights and a major barrier to achieving gender equality. Violence against women is increased in disaster-stricken communities. Violence experiences, cases, and lessons-learned concerning Iran's disasters have not been investigated, documented, or shared so far. To fill this knowledge gap, this qualitative study aimed to explore types of VAW and girls after the recent quakes and floods in Iran. Problem The objective for this study was exploring the manifestations of VAW after the natural disasters in Iran. A qualitative approach was used for this study. Data were collected by in-depth, unstructured interviews and field observations in three affected regions of Iran, including East Azerbaijan, Bushehr, and Mazandaran. A total of 15 participants, eight damaged women as well as seven key informants, were interviewed. A content analysis using Graneheim approach was performed for analyzing transcribed interviews. Two main themes were extracted from data, including domestic violence and violence within community. The first theme included three categories: physical, psychological, and sexual violence. Psychological violence and sexual harassment were two categories of violence within the community concept. Different types of violence emerged from the present research that can be anticipated and integrated into future disaster medicine plans, public health reforms, and national rules of Iran. Improving women's knowledge on their rights to have a life without violence, and participation of both women and men in violence reduction projects, can be considered in all disaster management phases. Sohrabizadeh S . A qualitative study of violence against women after the recent disasters of Iran. Prehosp Disaster Med. 2016;31(4):407-412.

Local knowledge: Empirical Fact to Develop Community Based Disaster Risk Management Concept for Community Resilience at Mangkang Kulon Village, Semarang City

NASA Astrophysics Data System (ADS)

Kapiarsa, A. B.; Sariffuddin, S.

2018-02-01

Local knowledge in disaster management should not be neglected in developing community resilience. The circular relation between humans and their living habitat and community social relation have developed the local knowledge namely specialized knowledge, shared knowledge, and common knowledge. Its correlation with community-based disaster management has become an important discussion specially to answer can local knowledge underlie community-based disaster risk reduction concept development? To answer this question, this research used mix-method. Interview and crosstab method for 73 respondents with 90% trust rate were used to determine the correlation between local knowledge and community characteristics. This research found out that shared knowledge dominated community local knowledge (77%). While common knowledge and specialized knowledge were sequentially 8% and 15%. The high score of shared value (77%) indicated that local knowledge was occurred in household level and not yet indicated in community level. Shared knowledge was found in 3 phases of the resilient community in dealing with disaster, namely mitigation, emergency response, and recovery phase. This research, therefore, has opened a new scientific discussion on the self-help concept in community-help concept in CBDRM concept development in Indonesia.

Lessons Learned from Southeast Asian Floods

NASA Astrophysics Data System (ADS)

Osti, R.; Tanaka, S.

2009-04-01

At certain scales, flood has always been the lifeline of many people from Southeast Asian countries. People are traditionally accustomed to living with such floods and their livelihood is adjusted accordingly to optimize the benefits from the floods. However, large scale flood occasionally turns into the disaster and causes massive destruction not only in terms of human causalities but also damage to economic, ecological and social harmonies in the region. Although economic growth is prevailing in a relative term, the capacity of people to cope with such extreme events is weakening therefore the flood disaster risk is increasing in time. Recent examples of flood disaster in the region clearly show the increasing severity of disaster impact. This study reveals that there are many factors, which directly or indirectly influence the change. This paper considers the most prominent natural and socio-economic factors and analyzes their trend with respect to flood disasters in each country's context. A regional scale comparative analysis further helps to exchange the know how and to determine what kind of strategy and policy are lacking to manage the floods in a long run. It is also helpful in identifying the critical sectors that should be addressed first to mitigate the potential damage from the floods.

Living and dying with glaciers: people's historical vulnerability to avalanches and outburst floods in Peru

NASA Astrophysics Data System (ADS)

Carey, Mark

2005-07-01

Human populations worldwide are vulnerable to natural disasters. Certain conditions—such as geographical location or people's income level—can affect the degree to which natural disasters impact people's homes and livelihoods. This paper suggests that vulnerability to natural disasters increases when local people, scientists, and policymakers do not communicate and trust each other. Additionally, a breakdown in interaction and confidence among these groups can disrupt the implementation of sound science or well-intentioned policies. This case study analyzes how local people, scientists, and government officials responded to glacier hazards in Peru's Cordillera Blanca mountain range. Cordillera Blanca glacier retreat since the late-19th century has triggered some of the world's most deadly avalanches and glacial lake outburst floods. Although a Peruvian glaciology and lakes security office has "controlled" 35 Cordillera Blanca glacial lakes, 30 glacier disasters have killed nearly 30,000 people in this region since 1941. A lack of local faith in government officials and scientists as well as the State's failure to follow scientists' warnings about potential disasters have endangered or led to the death of thousands of local residents, many of which remain living in hazard zones today.

Recasting Disaster Recovery Strategy at Dental Workplace in Combating Crisis – A Questionnaire Study

PubMed Central

Basavaraj, Patthi; Singla, Ashish; Gupta, Ritu; Kaur, Ravneet; Vashishtha, Vaibhav; Prasad, Monika; Kumar, Jishnu Krishna

2016-01-01

Introduction The number of reported natural and human-made disasters continues to rise worldwide. Disasters occur every day somewhere in the world with dramatic impact on individuals, families and communities. Aim This study was designed to measure the knowledge, attitude and practices regarding disaster management among academicians and practitioners in Ghaziabad city. Materials and Methods A cross-sectional study was conducted among 487 dentists. A questionnaire (15 items) measuring knowledge, attitude and practice was distributed manually to the participating dentists and data was analysed using SPSS software, version 19.0 and student t-test was performed to assess the differences. Results There was statistically significant relation between knowledge and attitude in relation to qualification degree, career prospective and years of experience (p <0.05). Conclusion Dentists form an important part of the health care community and thus there is a need to harvest the services of wide distribution of dentists practicing in our country. PMID:27190949

UAVSAR for the Management of Natural Disasters

NASA Astrophysics Data System (ADS)

Lou, Y.; Hensley, S.; Jones, C. E.

2014-12-01

The unique capabilities of imaging radar to penetrate cloud cover and collect data in darkness over large areas at high resolution makes it a key information provider for the management and mitigation of natural and human-induced disasters such as earthquakes, volcanoes, landslides, floods, and wildfires. Researchers have demonstrated the use of UAVSAR's fully polarimetric data to determine flood extent, forest fire extent, lava flow, and landslide. The ability for UAVSAR to provide high accuracy repeated flight tracks and precise imaging geometry for measuring surface deformation to a few centimeter accuracy using InSAR techniques. In fact, UAVSAR's repeat-pass interferometry capability unleashed new potential approaches to manage the risk of natural disasters prior to the occurrence of these events by modeling and monitoring volcano inflation, earthquake fault movements, landslide rate and extent, and sink hole precursory movement. In this talk we will present examples of applications of UAVSAR for natural disaster management. This research was conducted at the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

The resilience activation framework: a conceptual model of how access to social resources promotes adaptation and rapid recovery in post-disaster settings.

PubMed

Abramson, David M; Grattan, Lynn M; Mayer, Brian; Colten, Craig E; Arosemena, Farah A; Bedimo-Rung, Ariane; Lichtveld, Maureen

2015-01-01

A number of governmental agencies have called for enhancing citizens' resilience as a means of preparing populations in advance of disasters, and as a counterbalance to social and individual vulnerabilities. This increasing scholarly, policy, and programmatic interest in promoting individual and communal resilience presents a challenge to the research and practice communities: to develop a translational framework that can accommodate multidisciplinary scientific perspectives into a single, applied model. The Resilience Activation Framework provides a basis for testing how access to social resources, such as formal and informal social support and help, promotes positive adaptation or reduced psychopathology among individuals and communities exposed to the acute collective stressors associated with disasters, whether human-made, natural, or technological in origin. Articulating the mechanisms by which access to social resources activate and sustain resilience capacities for optimal mental health outcomes post-disaster can lead to the development of effective preventive and early intervention programs.

Mobile mental health interventions following war and disaster

PubMed Central

Kuhn, Eric; Jaworski, Beth K.; Owen, Jason E.; Ramsey, Kelly M.

2016-01-01

Mobile technologies offer potentially critical ways of delivering mental health support to those experiencing war, ethnic conflict, and human-caused and natural disasters. Research on Internet interventions suggests that effective mobile mental health technologies can be developed, and there are early indications that they will be acceptable to war and disaster survivors, and prove capable of greatly increasing the reach of mental health services. Promising mhealth interventions include video teleconferencing, text messaging, and smartphone-based applications. In addition, a variety of social media platforms has been used during and immediately after disasters to increase agility in responding, and strengthen community and individual resilience. Globally, PTSD Coach has been downloaded over 243,000 times in 96 countries, and together with large-scale use of social media for communication during disasters, suggests the potential for reach of app technology. In addition to enabling improved self-management of post-trauma problems, mobile phone interventions can also enhance delivery of face-to-face care by mental health providers and increase the effectiveness of peer helpers and mutual aid organizations. More research is needed to establish the efficacy of mhealth interventions for those affected by war and disaster. Research should also focus on the identification of active elements and core processes of change, determination of effective ways of increasing adoption and engagement, and explore ways of combining the various capabilities of mobile technologies to maximize their impact. PMID:28293610

Data Collection for Disaster Response from the International Space Station

NASA Astrophysics Data System (ADS)

Stefanov, W. L.; Evans, C. A.

2015-04-01

Remotely sensed data acquired by orbital sensor systems has emerged as a vital tool to identify the extent of damage resulting from a natural disaster, as well as providing near-real time mapping support to response efforts on the ground and humanitarian aid efforts. The International Space Station (ISS) is a unique terrestrial remote sensing platform for acquiring disaster response imagery. Unlike automated remote-sensing platforms it has a human crew; is equipped with both internal and externally-mounted remote sensing instruments; and has an inclined, low-Earth orbit that provides variable views and lighting (day and night) over 90 percent of the inhabited surface of the Earth. As such, it provides a useful complement to autonomous sensor systems in higher altitude polar orbits. NASA remote sensing assets on the station began collecting International Charter, Space and Major Disasters, also known informally as the International Disaster Charter (IDC) response data in May 2012. Since the start of IDC response in 2012, and as of late March 2015, there have been 123 IDC activations; NASA sensor systems have collected data for thirty-four of these events. Of the successful data collections, eight involved two or more ISS sensor systems responding to the same event. Data has also been collected by International Partners in response to natural disasters, most notably JAXA and Roscosmos/Energia through the Urugan program.

Mobile mental health interventions following war and disaster.

PubMed

Ruzek, Josef I; Kuhn, Eric; Jaworski, Beth K; Owen, Jason E; Ramsey, Kelly M

2016-01-01

Mobile technologies offer potentially critical ways of delivering mental health support to those experiencing war, ethnic conflict, and human-caused and natural disasters. Research on Internet interventions suggests that effective mobile mental health technologies can be developed, and there are early indications that they will be acceptable to war and disaster survivors, and prove capable of greatly increasing the reach of mental health services. Promising mhealth interventions include video teleconferencing, text messaging, and smartphone-based applications. In addition, a variety of social media platforms has been used during and immediately after disasters to increase agility in responding, and strengthen community and individual resilience. Globally, PTSD Coach has been downloaded over 243,000 times in 96 countries, and together with large-scale use of social media for communication during disasters, suggests the potential for reach of app technology. In addition to enabling improved self-management of post-trauma problems, mobile phone interventions can also enhance delivery of face-to-face care by mental health providers and increase the effectiveness of peer helpers and mutual aid organizations. More research is needed to establish the efficacy of mhealth interventions for those affected by war and disaster. Research should also focus on the identification of active elements and core processes of change, determination of effective ways of increasing adoption and engagement, and explore ways of combining the various capabilities of mobile technologies to maximize their impact.

Making cities resilient: Increasing resilience to disasters at the local level.

PubMed

Albrito, Paola

2012-01-01

Half of humanity is now living in cities, according to the United Nations Population Division. The urban population exceeded the rural for the first time in 2008, and by 2050 urbanisation will rise to 70 per cent with increased urban risk. 'Today, 100 cities are in control of 30 per cent of the world's economy.' The need for maintenance and upkeep of these cities makes safety measures for their citizens crucial. In this context, urban risk, city planning and the role of local governments in dealing with risk reduction have been recognised as key factors to build communities resilient to disasters. While many local governments have taken action to reduce vulnerability, especially when it comes to government organising capacity to deal with disasters, much remains to be done. Disaster risk has become an acute and increasingly urban issue. Poorly-planned urban environments, weak urban governance, an old and fragile infrastructure, and rapid population growth have increased pressure on the urban environment and triggered exposure to disaster risk. More and more people are settling in potential danger zones such as flood plains, volcanic flanks or earthquake faults and coastal areas. They do so because planners and local governments fail to provide alternatives, or because they cannot afford safer land. Local government officials are confronted with the threat of disasters daily, and need improved access to policies and tools to cope with them effectively.

The relevance of flood hazards and impacts in Turkey: What can be learned from different disaster loss databases?

NASA Astrophysics Data System (ADS)

Koc, Gamze; Thieken, Annegret H.

2016-04-01

Despite technological development, better data and considerable efforts to reduce the impacts of natural hazards over the last two decades, natural disasters inflicted losses have caused enormous human and economic damages in Turkey. In particular earthquakes and flooding have caused enormous human and economic losses that occasionally amounted to 3 to 4% of the gross national product of Turkey (Genç, 2007). While there is a large body of literature on earthquake hazards and risks in Turkey, comparatively little is known about flood hazards and risks. Therefore, this study is aimed at investigating flood patterns, intensities and impacts, also providing an overview of the temporal and spatial distribution of flood losses by analysing different databases on disaster losses throughout Turkey. As input for more detailed event analyses, an additional aim is to retrieve the most severe flood events in the period between 1960 and 2014 from the databases. In general, data on disaster impacts are scarce in comparison to other scientific fields in natural hazard research, although the lack of reliable, consistent and comparable data is seen as a major obstacle for effective and long-term loss prevention. Currently, only a few data sets, especially the emergency events database EM-DAT (www.emdat.be) hosted and maintained by the Centre for Research on the Epidemiology of Disasters (CRED) since 1988, are publicly accessible and have become widely used to describe trends in disaster losses. However, loss data are subjected to various biases (Gall et al. 2009). Since Turkey is in the favourable position of having a distinct national disaster database since 2009, i.e. the Turkey Disaster Data Base (TABB), there is the unique opportunity to investigate flood impacts in Turkey in more detail as well as to identify biases and underlying reasons for mismatches with EM-DAT. To compare these two databases, the events of the two databases were reclassified by using the IRDR peril classification system (IRDR, 2014). Furthermore, literature, news archives and the Global Active Archive of Large Flood Events - Dartmouth Flood Observatory (floodobservatory.colorado.edu) were used to complement loss data gaps of the databases. From 1960 to 2014, EM-DAT reported 35 flood events in Turkey (26.3 % of all natural hazards events), which caused 773 fatalities (the second most destructive type of natural hazard after earthquakes) and a total economic damage of US 2.2 billion. In contrast, TABB contained 1076 flood events (8.3 % of all natural hazards events), by which 795 people died. On this basis, floods are the third most destructive type of natural hazard -after earthquakes and extreme temperatures- for human losses in Turkey. A comparison of the two databases EM-DAT and TABB reveals big mismatches of the flood data, e.g. the reported number of events, number of affected people and economic loss, differ dramatically. It is concluded that the main reason for the big differences and contradicting numbers of different natural disaster databases is lack of standardization for data collection, peril classification and database thresholds (entry criteria). Since loss data collection is gaining more and more attention, e.g. in the Sendai Framework for Disaster Risk Reduction 2015-2030 (SFDRR), the study could offer substantial insights for flood risk mitigation and adaptation studies in Turkey. References Gall, M., Borden, K., Cutter, S.L. (2009) When do losses count? Six fallacies of loss data from natural hazards. Bulletin of the American Meteorological Society, 90(6), 799-809. Genç, F.S., (2007) Türkiye'de Kentleşme ve Doǧal Afet Riskleri ile İlişkisi, TMMOB Afet Sempozyumu. IRDR (2014) IRDR Peril Classification and Hazard Glossary. Report of the Data Group in the Integrated Research on Disaster Risk. (Available at: http://www.irdrinternational.org/2014/03/28/irdr-peril-classification-and-hazard-glossary).

The Global Emergency Observation and Warning System

NASA Technical Reports Server (NTRS)

Bukley, Angelia P.; Mulqueen, John A.

1994-01-01

Based on an extensive characterization of natural hazards, and an evaluation of their impacts on humanity, a set of functional technical requirements for a global warning and relief system was developed. Since no technological breakthroughs are required to implement a global system capable of performing the functions required to provide sufficient information for prevention, preparedness, warning, and relief from natural disaster effects, a system is proposed which would combine the elements of remote sensing, data processing, information distribution, and communications support on a global scale for disaster mitigation.

Gulf Coast oil disaster: impact on human reproduction.

PubMed

Merhi, Zaher O

2010-10-01

The catastrophic British Petroleum oil spill in the Gulf of Mexico has reached the shores of the United States, along with unpredictable effects on the health of local communities. The potential impact of the disaster on female and male reproduction will be discussed in this report, to provide greater clinician awareness about the potential consequences of this calamity and to call for more research on this subject. Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Stress among police body handlers. A long-term follow-up.

PubMed

Alexander, D A

1993-12-01

Thirty-five police officers were followed up three years after they had been first assessed following their involvement in the retrieval and identification of human remains after a major disaster. Most of these officers were free from signs of psychiatric morbidity. Organisational and managerial practices appear to be powerful antidotes to adverse post-traumatic reactions. In this study the use of a longitudinal design, with a pre-disaster baseline and a control group, suggests that these are robust findings.

[Climate change, floods and health intervention].

PubMed

Furu, Peter; Tellier, Siri; Vestergaard, Lasse S

2017-05-15

Climate change and variability are considered some of the biggest threats to human health in the 21st century. Extreme weather events such as floods and storms are examples of natural hazards resulting in highest number of disasters and with considerable mortality and morbidity among vulnerable communities. A coordinated, well-planned management of health interventions must be taken for timely action in the response, recovery, prevention and preparedness phases of disasters. Roles and responsibilities of international as well as national organizations and authorities are discussed.

Application to space foods of the disaster food

NASA Astrophysics Data System (ADS)

Katayama, Naomi; Okano, Yukimi

2016-07-01

A long-term stay in the space of the human was enabled.The astronaut became able to stay in the long-term space for 1 from a half year.One of the pleasure in the space of the astronaut has a meal.The astronaut is chosen from each country.Therefore the space foods are full of variety.It wants to make the meal a universal meal to be able to do it.In addition, the space foods think about health and want to make a low salt diet. Nourishment balance of the meal eaten in space is regulated now. However, the meal which a hyperglycosemia level after a meal does not happen more than now is necessary.In addition, a low salt diet is necessary for hypertensive prevention. This accords with disaster food in the ground. The nutrient which is enough to take in the disaster foods for a long term is necessary. We need a meal suppressing the hyperglycosemia after a meal in a low salt diet as a disaster meal. Therefore I thought that we applied a disaster meal to space foods. We can store the disaster food at normal temperature for 3-5 years.It is necessary to be able to store the space foods at normal temperature more than three years. The nutrient that both the space foods and the disaster meal are short includes vitamins. We think that it is necessary to supplement it with a supplement about the intake of vitamins. This accords with disaster food in the ground.I thought about space foods menu with commercially available disaster food now in Japan. After all salt to take in per day increases.Most of the energy from carbohydrates is taken in. It is necessary to have vegetables. I think that it can make up for part of vitamins if I can make fresh vegetables in space. A supplement is necessary for the supply of vitamins. I think that multivitamin is good if possible.

Assessing the economic impacts of drought from the perspective of profit loss rate: a case study of the sugar industry in China

NASA Astrophysics Data System (ADS)

Wang, Y.; Lin, L.; Chen, H.

2015-07-01

Natural disasters have enormous impacts on human society, especially on the development of the economy. To support decision-making in mitigation and adaption to natural disasters, assessment of economic impacts is fundamental and of great significance. Based on a review of the literature on economic impact evaluation, this paper proposes a new assessment model of the economic impacts of droughts by using the sugar industry in China as a case study, which focuses on the generation and transfer of economic impacts along a simple value chain involving only sugarcane growers and a sugar-producing company. A perspective of profit loss rate is applied to scale economic impact. By using "with and without" analysis, profit loss is defined as the difference in profits between disaster-hit and disaster-free scenarios. To calculate profit, analysis of a time series of sugar price is applied. With the support of a linear regression model, an endogenous trend in sugar price is identified and the time series of sugar price "without" disaster is obtained, using an autoregressive error model to separate impact of disasters from the internal trend in sugar price. Unlike the settings in other assessment models, representative sugar prices, which represent value level in disaster-free conditions and disaster-hit conditions, are integrated from a long time series that covers the whole period of drought. As a result, it is found that in a rigid farming contract, sugarcane growers suffer far more than the sugar company when impacted by severe drought, which may promote reflections among various economic bodies on economic equality related to the occurrence of natural disasters. Further, sensitivity analysis of the model built reveals that sugarcane purchase price has a significant influence on profit loss rate, which implies that setting a proper sugarcane purchase price would be an effective way of realizing economic equality in future practice of contract farming.

Teaching a Course in Natural Disasters: Geoethics and the Layman

NASA Astrophysics Data System (ADS)

Fryer, P.

2009-12-01

One graduation requirement of the University of Hawaii at Manoa is that students must take an “Ethics Focus” class at the Junior/Senior level. It is to the advantage of departments to offer such classes to majors. I designed and taught a class entitled “Natural Disasters: Geoethics and the Layman” in the Spring of ‘09. The prerequisite was an introductory Geology class. The objectives were: (1) To define ethics, from philosophical points of view and as a personal framework for making decisions about issues related to natural disasters. The Chair of the Philosophy Department assisted in the initial classes to teach the basic principles of ethical thinking. (2) To define what constitutes a “natural” disaster vs what constitutes a disaster brought about by the imposition of human imperatives on the natural world (e.g., to build seawalls or not in efforts to mitigate against beach erosion). (3) To explore a variety of controversial issues at the intersections of two or more of the following: natural processes, human society, and the environment (e.g., forecasting the potential for violent volcanic eruption and understanding the effects of such forecasts on the safety of proximal human populations vs economic disaster caused by evacuation or loss of revenue affected by "false alarms"). (4) To improve the students’ oral communication skills, both as individuals and as members of cooperating groups. (5) To develop and practice using ethically- and scientifically-valid frameworks for reaching decisions about controversial science-based issues. (6) To learn about local organizations, businesses, government agencies, the media and individuals in society who are involved with reacting to and developing solutions for response to these events and their related ethical issues. Students wrote 1- to 2-page journal essays on the issues discussed in class each week and a term paper on issues related to a “natural disaster” of their choice. The 3-credit class brought individuals from academia, private industry, the military, and from civic, state, and federal government agencies into the classroom each week to present information about their experiences, to present reality checks on aspects of actual disaster situations, and to answer student questions. The difficulty was working around guest speakers’ schedules. Student feedback to the class was generally positive, reactions included: “Best part? Getting to talk to real scientists.” ; “You can’t “teach“ ethics, either you have them or you don’t.” ; “I really liked the “student panel” there should be more of them and less lecturing.” ; “This should be a “writing-intensive” class.”

Challenges of Tsunami Disaster and Extreme climate Events Along Coastal Region in Asia-Pacific

NASA Astrophysics Data System (ADS)

Chaudhari, S.

2017-12-01

South Asia is more vulnerable to Geo disasters and impacts of climate changes in recent years. On 26 December 2004 massive waves triggered by an earthquake surged into coastal communities in Asia and East Africa with devastating force. Hitting Indonesia, Sri Lanka , Thailand and India hardest, the deadly waves swept more than 200 000 people to their deaths. Also in an another extreme climate change phenomenon during 2005 - 2006,causing heavy rains and flooding situation in the South Asia - Europe and Pacific region ,more than 100 million population in these regions are witnessing the social- economical and ecological risks and impacts due to climate changes and Geohazards. For mitigating geo-disasters, marine hazards and rehabilitation during post tsunami period, scientific knowledge is needed, requiring experienced research communities who can train the local population during tsunami rehabilitation. Several civil society institutions jointly started the initiatives on the problem identifications in management of risks in geo-disasters, tsunami rehabilitation ,Vulnerability and risk assessments for Geohazards etc., to investigate problems related to social-economic and ecological risks and management issues resulting from the December tsunami and Geo- disaster, to aid mitigation planning in affected areas and to educate scientists and local populations to form a basis for sustainable and economic solutions. The poster aims to assess the potential risk and hazard , technical issues, problems and damage arising from Tsunami in the Asia-pacific region in coastal geology, coastal ecosystems and coastal environmental systems . This poster deals with the status and issues of interactions between Human and Ocean Systems, Geo-risks, marine risks along coastal region of Asia- Pacific and also human influence on the earth system . The poster presentation focuses on capacity building of the local population, scientists and researchers for integration of human and ocean systems through Geohazards Studies on vulnerability and risk assessments along coastal regions. The poster presentation also focuses on building natural -social science research community for sustainable solutions adoptions and mitigations of impacts of extreme climate events on environment and ecosystems along coastal region.

Management of disasters and complex emergencies in Africa: The challenges and constraints.

PubMed

Aliyu, Alhaji

2015-01-01

Natural and man-made catastrophes have caused significant destruction and loss of lives throughout human history. Disasters accompany a wide variety of events with multiple causes and consequences often leading to a cascade of related events. African continent has not been spared of these events. A new phenomenon in the continent is terrorism that is fuelled by globalization of arms trade and has contributed significantly to escalation of conflicts in sub-Saharan Africa (SSA) resulting in complex emergencies and destruction of socioeconomic structures. The aim of this paper is to review relevant papers on management of disasters and complex emergencies in Africa and the challenges and constraints against the background of a weakened health system. Systematic search of published literature was conducted between 1990 and 2013. Grey literature (technical reports, government documents), published peer review journals, abstracts, relevant books and internet articles were reviewed. The review revealed that the frequency of both natural and man-made disasters in Africa is escalating. Complex emergencies are also on the increase since the Rwandan crisis in 1994. The impact of these events has overstretched and overwhelmed the health care system that is least prepared to handle and cope with the surge capacity and also render normal services. In conclusion, there is an urgent need for national emergency agencies/departments across Africa to develop a robust emergency preparedness and response plan. Every hospital most have a disaster management committee with flexible disaster management plan to respond to these catastrophes. There is a need for curriculum review in tertiary institutions across SSA to introduce and or expand training in disaster management.

WCDRR and the CEOS activities on disaters

NASA Astrophysics Data System (ADS)

Petiteville, I.; Ishida, C.; Danzeglocke, J.; Eddy, A.; Gaetani, F.; Frye, S.; Kuligowski, B.; Zoffoli, S.; Poland, M.; Jones, B.

2015-04-01

Agencies from CEOS (Committee on Earth Observation Satellites) have traditionally focused their efforts on the response phase. Rapid urbanization and increased severity of weather events has led to growing economic and human losses from disasters, requiring international organisations to act now in all disaster risk management (DRM) phases, especially through improved disaster risk reduction policies and programmes. As part of this effort, CEOS agencies have initiated a series of actions aimed at fostering the use of Earth observation (EO) data to support disaster risk reduction and at raising the awareness of policy and decision-makers and major stakeholders of the benefits of using satellite EO in all phases of DRM. CEOS is developing a long-term vision for sustainable application of satellite EO to all phases of DRM. CEOS is collaborating with regional representatives of the DRM user community, on a multi-hazard project involving three thematic pilots (floods, seismic hazards and volcanoes) and a Recovery Observatory that supports resilient recovery from one major disaster. These pilot activities are meant as trail blazers that demonstrate the potential offered by satellite EO for comprehensive DRM. In the framework of the 2015 3rd World Conference on Disaster Risk Reduction (WCDRR), the CEOS space agencies intend to partner with major stakeholders, including UN organizations, the Group on Earth Observations (GEO), international relief agencies, leading development banks, and leading regional DRM organisations, to define and implement a 15-year plan of actions (2015- 2030) that responds to high-level Post-2015 Framework for Disaster Risk Reduction priorities. This plan of action will take into account lessons learned from the CEOS pilot activities.

Can I Get a Second Opinion? - Translating Hazard Understanding to Disaster Response

NASA Astrophysics Data System (ADS)

Green, D. S.; Stough, T.; Murray, J. J.

2015-12-01

Policy makers, operational response agencies and scientists are aware that when addressing hazard events decisions must be made in a timely manner with limited environmental information or less than 100% certainty. This presentation will examine how lessons captured from disaster events are mainstreaming the use of global earth observation data and derived products of sufficient reliability and timeliness to provide situational awareness. What is good enough for disaster response is a challenge, especially where the requirements for earth system research and experimentation are not the same as application science and operations. In areas of timeliness and access to data or processing of information to knowledge the economic and policy objectives are not always aligned between research and application. Even when both are addressing substantive science area questions and critical data is available, creating scientifically-informed guidance, forecasts and assessments may take considerable effort to be made accessible and understandable, and even longer to reflect consensus or consistency. Conveying the degree of science certainty and accountability that triggers a threshold for action is always a challenge at the interface of hazard characterization and disaster response. Often decisions and interpretation must be reached when staring down a hazard or potential disaster situation, which makes automation a potential solution. Yet human opinions remain important, social cultural and behavioral context suggest that observational information, maps, models and other derived information is only acted upon when provided by multiple trusted and reliable sources. This presentation will discuss examples drawn from NASA's research and partnership portfolio in disaster application science and explore strategic approaches to strengthen disaster risk reduction and resilience.

Cyclic Sulfamidate Enabled Syntheses of Amino Acids, Peptides, Carbohydrates, and Natural Products

EPA Science Inventory

This article reviews the emergence of cyclic sulfamidates as versatile intermediatesfor the synthesis of unnatural amino acids, chalcogen peptides, modified sugars, drugs and drug candidates, and important natural products.

Hair transplant

MedlinePlus

... this procedure: Scarring Unnatural-looking tufts of new hair growth It is possible that the transplanted hair will ... Most hair transplants result in excellent hair growth within several ... may be needed to create best results. The replaced hairs are ...

Ondansetron and granisetron binding orientation in the 5-HT(3) receptor determined by unnatural amino acid mutagenesis.

PubMed

Duffy, Noah H; Lester, Henry A; Dougherty, Dennis A

2012-10-19

The serotonin type 3 receptor (5-HT(3)R) is a ligand-gated ion channel found in the central and peripheral nervous systems. The 5-HT(3)R is a therapeutic target, and the clinically available drugs ondansetron and granisetron inhibit receptor activity. Their inhibitory action is through competitive binding to the native ligand binding site, although the binding orientation of the drugs at the receptor has been a matter of debate. Here we heterologously express mouse 5-HT(3)A receptors in Xenopus oocytes and use unnatural amino acid mutagenesis to establish a cation-π interaction for both ondansetron and granisetron to tryptophan 183 in the ligand binding pocket. This cation-π interaction establishes a binding orientation for both ondansetron and granisetron within the binding pocket.

Ondansetron and Granisetron Binding Orientation in the 5-HT3 Receptor Determined by Unnatural Amino Acid Mutagenesis

PubMed Central

Duffy, Noah H.; Lester, Henry A.; Dougherty, Dennis A.

2012-01-01

The serotonin type 3 receptor (5-HT3R) is a ligand-gated ion channel that mediates fast synaptic transmission in the central and peripheral nervous systems. The 5-HT3R is a therapeutic target, and the clinically available drugs ondansetron and granisetron inhibit receptor activity. Their inhibitory action is through competitive binding to the native ligand binding site, although the binding orientation of the drugs at the receptor has been a matter of debate. Here we heterologously express mouse 5-HT3A receptors in Xenopus oocytes and use unnatural amino acid mutagenesis to establish a cation-π interaction for both ondansetron and granisetron to tryptophan 183 in the ligand binding pocket. This cation-π interaction establishes a binding orientation for both ondansetron and granisetron within the binding pocket. PMID:22873819

The museum of unnatural form: a visual and tactile experience of fractals.

PubMed

Della-Bosca, D; Taylor, R P

2009-01-01

A remarkable computer technology is revolutionizing the world of design, allowing intricate patterns to be created with mathematical precision and then 'printed' as physical objects. Contour crafting is a fabrication process capable of assembling physical structures the sizes of houses, firing the imagination of a new generation of architects and artists (Khoshnevisat, 2008). Daniel Della-Bosca has jumped at this opportunity to create the 'Museum of Unnatural Form' at Griffith University. Della-Bosca's museum is populated with fractals sculptures - his own versions of nature's complex objects - that have been printed with the new technology. His sculptures bridge the historical divide in fractal studies between the abstract images of mathematics and the physical objects of Nature (Mandelbrot, 1982). Four of his fractal images will be featured on the cover of NDPLS in 2009.

"Unnatural Fornication" Cases Under State-Socialism: A Hungarian-Slovenian Comparative Social-Historical Approach.

PubMed

Takács, Judit; Kuhar, Roman; Tóth, Tamás P

2017-01-01

This comparative social-historical study examines different versions of state-socialist body politics manifested in Hungary and Slovenia mainly during the 1950s by using archive material of "unnatural fornication" court cases. By analyzing the available Hungarian "természet elleni fajtalanság" and Slovenian "nenaravno občevanje" court cases, we can shed light on how the defendants were treated by the police and the judiciary. On the basis of these archive data that have never been examined before from these angles, we can construct an at least partial picture of the practices and consequences of state surveillance of same-sex-attracted men during state-socialism. The article explores the functioning of state-socialist social control mechanisms directed at nonnormative sexualities that had long-lasting consequences on the social representation of homosexuality in both countries.

An engineered bacterium auxotrophic for an unnatural amino acid: a novel biological containment system

PubMed Central

2015-01-01

Biological containment is a genetic technique that programs dangerous organisms to grow only in the laboratory and to die in the natural environment. Auxotrophy for a substance not found in the natural environment is an ideal biological containment. Here, we constructed an Escherichia coli strain that cannot survive in the absence of the unnatural amino acid 3-iodo-L-tyrosine. This synthetic auxotrophy was achieved by conditional production of the antidote protein against the highly toxic enzyme colicin E3. An amber stop codon was inserted in the antidote gene. The translation of the antidote mRNA was controlled by a translational switch using amber-specific 3-iodo-L-tyrosine incorporation. The antidote is synthesized only when 3-iodo-L-tyrosine is present in the culture medium. The viability of this strain rapidly decreased with less than a 1 h half-life after removal of 3-iodo-L-tyrosine, suggesting that the decay of the antidote causes the host killing by activated colicin E3 in the absence of this unnatural amino acid. The contained strain grew 1.5 times more slowly than the parent strains. The escaper frequency was estimated to be 1.4 mutations (95% highest posterior density 1.1–1.8) per 105 cell divisions. This containment system can be constructed by only plasmid introduction without genome editing, suggesting that this system may be applicable to other microbes carrying toxin-antidote systems similar to that of colicin E3. PMID:26401457

COMMUNICATION Designing a somatosensory neural prosthesis: percepts evoked by different patterns of thalamic stimulation

NASA Astrophysics Data System (ADS)

Heming, Ethan; Sanden, Andrew; Kiss, Zelma H. T.

2010-12-01

Although major advances have been made in the development of motor prostheses, fine motor control requires intuitive somatosensory feedback. Here we explored whether a thalamic site for a somatosensory neural prosthetic could provide natural somatic sensation to humans. Different patterns of electrical stimulation (obtained from thalamic spike trains) were applied in patients undergoing deep brain stimulation surgery. Changes in pattern produced different sensations, while preserving somatotopic representation. While most percepts were reported as 'unnatural', some stimulations produced more 'natural' sensations than others. However, the additional patterns did not elicit more 'natural' percepts than high-frequency (333 Hz) electrical stimulation. These features suggest that despite some limitations, the thalamus may be a feasible site for a somatosensory neural prosthesis and different stimulation patterns may be useful in its development.

Health impact of the 2004 Andaman Nicobar earthquake and tsunami in Indonesia.

PubMed

Guha-Sapir, Debarati; van Panhuis, Willem Gijsbert

2009-01-01

The human impact of the tsunami that occurred on 26 December 2004 was enormous, with Indonesia bearing a huge proportion of the losses. The aftermath brought predictions of communicable disease outbreaks and widespread fear of epidemics. However, evidence from previous disasters due to natural hazards does not support all of these predictions. The objectives of this study were to: (1) describe the relative importance of infectious diseases and injuries as a consequence of a disaster due to natural hazards; and (2) identify key recommendations for the improvement of control and surveillance of these diseases during and after disasters. A team from the Center for Research on the Epidemiology of Disasters visited Jakarta and Banda Aceh from 11-23 January 2005, and collected data from the Central and Provincial Ministries of Health (MOH), the World Health Organization (WHO), and a field hospital from the International Committee of the Red Cross in Banda Aceh. The epidemiological profiles of diseases before and after the tsunami were compared. Cholera, tetanus, wounds and wound infections, acute respiratory infections, malaria, and dengue were included in this analysis. Certain diseases (e.g., cholera, malaria, dengue) are not always an immediate priority post-disaster. Rates of disaster-related health conditions requiring emergency response fell by half, and became negligible around four weeks after the precipitating events. Some conditions, such as aspiration pneumonia and tetanus, which normally are rare, require special preparedness for emergency personnel. In addition, resistant and rare pathogens are associated with disasters due to natural hazards in the tropics and require specialized knowledge for the rapid and successful treatment of related infections. Within the first four weeks of a disaster, international humanitarian agencies in the health sector should start working with the MOH. The WHO surveillance system established immediately after the tsunami offers lessons for developing a prototype for future emergencies. Guidelines for tetanus and aspiration pneumonia should be included in disaster medicine handbooks, and humanitarian aid groups should be prepared to provide emergency obstetrics and post-natal services. Relief funding after naturally occurring disasters should consider funding sustainability. Donors should know when to stop providing emergency relief funds and transition to recovery/development strategies.

Environmental Resilience: Exploring Scientific Concepts for ...

EPA Pesticide Factsheets

Report This report summarizes two Community Environmental Resilience Index workshops held at EPA in May and July of 2014. The workshops explored scientific concepts for building an index of indicators of community environmental resilience to natural or human-caused disasters. The index could be used to support disaster decision-making. Key workshop outcomes include: a working definition of environmental resilience and insight into how it relates to EPA's mission and Strategic Goals, a call for an inventory of EPA resiliency tools, a preliminary list of indicators and CERI structure, identification of next steps for index development, and emergence of a network of collaborators. The report can be used to support EPA's work in resilience under PPD-8, PPD-21, and the national response and disaster recovery frameworks. It can feed into interagency efforts on building community resilience.

Report on the costs of domestic and international emergencies and on the threats posed by the Kuwaiti oil fires as required by P. L. 102-55

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-06-01

The report fulfills the requirements of Public Law 12-55, the FY 1992 dire emergency supplemental appropriations bill, signed by the President on June 13, 1991. This law required the Director of the Office of Management and Budget to prepare and submit to the appropriate committees of Congress a report on: unfunded costs of dire emergencies because of floods, droughts, tornadoes, unemployment, and other disasters in the United States; unfunded costs, including food assistance, of international disaster emergencies existing because of floods, droughts, tornadoes, and other disasters; and the threats to oil supply, human health, and the environment that the Kuwaitimore » oil fires might pose.« less

The Hindenburg Disaster: Combining Physics and History in the Laboratory

NASA Astrophysics Data System (ADS)

DiLisi, Gregory A.

2017-05-01

This May marks the 80th anniversary of the Hindenburg disaster. On May 6, 1937, the German passenger zeppelin Hindenburg, hovering 300 feet in the air and held aloft by seven million cubic feet of hydrogen gas, burst into flames while preparing to dock at the Naval Air Station in Lakehurst, NJ (Fig. 1). Amazingly, the ensuing fire consumed the massive airship in only 35 seconds! In the aftermath, 35 of 97 people onboard died (13 passengers and 22 crewmen) plus one member of the ground crew. Herbert Morrison, the broadcaster from Chicago's WLS radio station, was on assignment that day covering the arrival of the majestic airship. Morrison's eyewitness account of the disaster is legendary audio history. In fact, Morrison's phrase, "Oh, the humanity!" has become a cultural idiom.

Dynamic model of forest area on flood zone of Padang City, West Sumatra Province-Indonesia

NASA Astrophysics Data System (ADS)

Dewata, Indang; Iswandi, U.

2018-05-01

The flood disaster has caused many harm to human life, and the change of watershed characteristic is one of the factors causing the flood disaster. The increase of deforestation due to the increase of water causes the occurrence of flood disaster in the rainy season. The research objective was to develop a dynamic model of forest on flood hazard zone using powersim 10.1. In model development, there are three scenarios: optimistic, moderate, and pessimistic. The study shows that in Padang there are about 13 percent of high flood hazard zones. Deforestation of 4.5 percent/year is one cause that may increased the flooding intensity in Padang. There will be 14 percent of total forest area when management policy of forest absence in 2050.

Wind turbines and idiopathic symptoms: The confounding effect of concurrent environmental exposures.

PubMed

Blanes-Vidal, Victoria; Schwartz, Joel

2016-01-01

Whether or not wind turbines pose a risk to human health is a matter of heated debate. Personal reactions to other environmental exposures occurring in the same settings as wind turbines may be responsible of the reported symptoms. However, these have not been accounted for in previous studies. We investigated whether there is an association between residential proximity to wind turbines and idiopathic symptoms, after controlling for personal reactions to other environmental co-exposures. We assessed wind turbine exposures in 454 residences as the distance to the closest wind turbine (Dw) and number of wind turbines <1000m (Nw1000). Information on symptoms, demographics and personal reactions to exposures was obtained by a blind questionnaire. We identified confounders using confounders' selection criteria and used adjusted logistic regression models to estimate associations. When controlling only for socio-demographic characteristics, log10Dw was associated with "unnatural fatigue" (ORadj=0.38, 95%CI=0.15-1.00) and "difficulty concentrating" (ORadj=0.26, 95%CI=0.08-0.83) and Nw1000 was associated with "unnatural fatigue" (ORadj=1.35, 95%CI=1.07-1.70) and "headache" (ORadj=1.26, 95%CI=1.00-1.58). After controlling for personal reactions to noise from sources different from wind turbines and agricultural odor exposure, we did not observe a significant relationship between residential proximity to wind turbines and symptoms and the parameter estimates were attenuated toward zero. Wind turbines-health associations can be confounded by personal reactions to other environmental co-exposures. Isolated associations reported in the literature may be due to confounding bias. Copyright © 2016 Elsevier Inc. All rights reserved.

Global Perspectives on Resilience in Children and Youth

ERIC Educational Resources Information Center

Masten, Ann S.

2014-01-01

Global concerns about the consequences of disasters, political violence, disease, malnutrition, maltreatment, and other threats to human development and well-being have sparked a surge of international interest in resilience science. This article highlights progress and issues in research that aims to understand variations in human adaptation to…

7 CFR 760.1102 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... period. Adult dairy cow means a female bovine animal used for the purpose of providing milk for human... milk for human consumption, that weighed 500 pounds or more on the beginning date of the disaster... omnivorous pig, hog, and boar. Swine are further delineated by sex and weight as determined by FSA. ...

7 CFR 760.1102 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... period. Adult dairy cow means a female bovine animal used for the purpose of providing milk for human... milk for human consumption, that weighed 500 pounds or more on the beginning date of the disaster... omnivorous pig, hog, and boar. Swine are further delineated by sex and weight as determined by FSA. ...

7 CFR 760.1102 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... period. Adult dairy cow means a female bovine animal used for the purpose of providing milk for human... milk for human consumption, that weighed 500 pounds or more on the beginning date of the disaster... omnivorous pig, hog, and boar. Swine are further delineated by sex and weight as determined by FSA. ...

10 CFR 217.20 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... warehousing, ports, services, equipment and facilities, such as transportation carrier shop and repair... from: (1) A natural disaster; or (2) An accidental or human-caused event. Health resources means drugs...

10 CFR 217.20 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... warehousing, ports, services, equipment and facilities, such as transportation carrier shop and repair... from: (1) A natural disaster; or (2) An accidental or human-caused event. Health resources means drugs...

10 CFR 217.20 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... warehousing, ports, services, equipment and facilities, such as transportation carrier shop and repair... from: (1) A natural disaster; or (2) An accidental or human-caused event. Health resources means drugs...

Cascading disasters in the huge coastal aquifer of Salento (Apulia region, Southern Italy) ensuing droughts

NASA Astrophysics Data System (ADS)

Parisi, Alessandro; Fidelibus, Maria Dolores

2017-04-01

Physical extremes can be distinguished in "sudden physical extremes" (e.g. earthquakes, tsunami) and "progressive physical extremes" (e.g. drought, desertification, landslides). They differ for frequency, intensity, spatial extent, duration and timing of occurrence. If a physical extreme, by interacting with human systems, induces negative consequences, its outcome can be a "disaster". The disasters are, in both above cases, characterized by a few phases: physical extreme occurrence, emergency, response, and recovery. However, in the case of a progressive physical extreme, the disaster develops with an overlap in the time of the above-mentioned phases. When the events are repetitive, the emergency planning (which follows a cycle) succeeds with preparedness and mitigation with the intent of reducing the risk. Both the sudden and progressive physical extremes produce cascading effects of consequences on social, environmental and economic systems. Disasters consequent to sudden and progressive extremes show, however, some differences, mainly attributable to the "visibility" of the effects and to their time scale of evolution. As matter of fact, a disaster consequent to a progressive physical extreme produces "emerging signals" that are often invisible. Moreover, the emergency phase can arise with a time delay compared to the occurrence of the physical extreme, depending on the spatial scale of impacted system. The above differences allow defining "creeping disasters" the potential disasters related to progressive physical extremes. This study deals with some peculiar "cascading disasters" consequent to drought, which is the main "creeping disaster", namely the groundwater drought and the consequent salinization of coastal aquifers. In regional flow systems, their effects are invisible in the immediate to common people (and often even to managers) because of the concealed nature of groundwater; moreover, they are difficult to assess because of the shift over time of their evolution compared to the promptness of surface effects. The study area is the Salento coastal karstic aquifer (Apulia region, Southern Italy), where the groundwater flows according to a regional flow system. It has been subject to successive meteorological droughts between 1960 and 2010. The groundwater monitoring performed during this period, even with some gaps, allows identifying time lags between superficial effects and underground system response, potential tipping points, and emerging signals of the cascading disasters.

Committee Opinion No. 726 Summary: Hospital Disaster Preparedness for Obstetricians and Facilities Providing Maternity Care.

PubMed

2017-12-01

Large-scale catastrophic events and infectious disease outbreaks highlight the need for disaster planning at all community levels. Features unique to the obstetric population (including antepartum, intrapartum, postpartum and neonatal care) warrant special consideration in the event of a disaster. Pregnancy increases the risks of untoward outcomes from various infectious diseases. Trauma during pregnancy presents anatomic and physiologic considerations that often can require increased use of resources such as higher rates of cesarean delivery. Recent evidence suggests that floods and human-influenced environmental disasters increase the risks of spontaneous miscarriages, preterm births, and low-birth-weight infants among pregnant women. The potential surge in maternal and neonatal patient volume due to mass-casualty events, transfer of high-acuity patients, or redirection of patients because of geographic barriers presents unique challenges for obstetric care facilities. These circumstances require that facilities plan for additional increases in necessary resources and staffing. Although emergencies may be unexpected, hospitals and obstetric delivery units can prepare to implement plans that will best serve maternal and pediatric care needs when disasters occur. Clear designation of levels of maternal and neonatal care facilities, along with establishment of a regional network incorporating hospitals that provide maternity services and those that do not, will enable rapid transport of obstetric patients to the appropriate facilities, ensuring the right care at the right time. Using common terminology for triage and transfer and advanced knowledge of regionalization and levels of care will facilitate disaster preparedness.

Committee Opinion No. 726: Hospital Disaster Preparedness for Obstetricians and Facilities Providing Maternity Care.

PubMed

2017-12-01

Large-scale catastrophic events and infectious disease outbreaks highlight the need for disaster planning at all community levels. Features unique to the obstetric population (including antepartum, intrapartum, postpartum and neonatal care) warrant special consideration in the event of a disaster. Pregnancy increases the risks of untoward outcomes from various infectious diseases. Trauma during pregnancy presents anatomic and physiologic considerations that often can require increased use of resources such as higher rates of cesarean delivery. Recent evidence suggests that floods and human-influenced environmental disasters increase the risks of spontaneous miscarriages, preterm births, and low-birth-weight infants among pregnant women. The potential surge in maternal and neonatal patient volume due to mass-casualty events, transfer of high-acuity patients, or redirection of patients because of geographic barriers presents unique challenges for obstetric care facilities. These circumstances require that facilities plan for additional increases in necessary resources and staffing. Although emergencies may be unexpected, hospitals and obstetric delivery units can prepare to implement plans that will best serve maternal and pediatric care needs when disasters occur. Clear designation of levels of maternal and neonatal care facilities, along with establishment of a regional network incorporating hospitals that provide maternity services and those that do not, will enable rapid transport of obstetric patients to the appropriate facilities, ensuring the right care at the right time. Using common terminology for triage and transfer and advanced knowledge of regionalization and levels of care will facilitate disaster preparedness.

Environmental exposures due to natural disasters.

PubMed

Knap, Anthony H; Rusyn, Ivan

2016-03-01

The environmental mobilization of contaminants by "natural disasters" is a subject of much interest, however, little has been done to address these concerns, especially in the developing world. Frequencies and predictability of events, both globally and regionally as well as the intensity, vary widely. It is clear that there are greater probabilities for mobilization of modern contaminants in sediments. Over the past 100 years of industrialization many chemicals are buried in riverine, estuarine and coastal sediments. There are a few studies, which have investigated this potential risk especially to human health. Studies that focus on extreme events need to determine the pre-existing baseline, determine the medium to long term fate and transport of contaminants and investigate aquatic and terrestrial pathways. Comprehensive studies are required to investigate the disease pathways and susceptibility for human health concerns.

Recovery Migration After Hurricanes Katrina and Rita: Spatial Concentration and Intensification in the Migration System.

PubMed

Curtis, Katherine J; Fussell, Elizabeth; DeWaard, Jack

2015-08-01

Changes in the human migration systems of the Gulf of Mexico coastline counties affected by Hurricanes Katrina and Rita provide an example of how climate change may affect coastal populations. Crude climate change models predict a mass migration of "climate refugees," but an emerging literature on environmental migration suggests that most migration will be short-distance and short-duration within existing migration systems, with implications for the population recovery of disaster-stricken places. In this research, we derive a series of hypotheses on recovery migration predicting how the migration system of hurricane-affected coastline counties in the Gulf of Mexico was likely to have changed between the pre-disaster and the recovery periods. We test these hypotheses using data from the Internal Revenue Service on annual county-level migration flows, comparing the recovery period migration system (2007-2009) with the pre-disaster period (1999-2004). By observing county-to-county ties and flows, we find that recovery migration was strong: the migration system of the disaster-affected coastline counties became more spatially concentrated, while flows within it intensified and became more urbanized. Our analysis demonstrates how migration systems are likely to be affected by the more intense and frequent storms anticipated by climate change scenarios, with implications for the population recovery of disaster-affected places.

Hospital Disaster Preparedness in Italy: a preliminary study utilizing the World Health Organization Hospital Emergency Response Evaluation Toolkit.

PubMed

Ingrassia, Pier L; Mangini, Marco; Azzaretto, Massimo; Ciaramitaro, Ilenia; Costa, Laura; Burkle, Frederick M; Della Corte, Francesco; Djalali, Ahmadreza

2016-12-01

Natural and human-initiated disasters are occurring with greater devastating consequences and increased frequency. During these events, hospitals have the burden to care for acutely ill and injured patients. The aim of this study was to evaluate the level of disaster preparedness of Italian hospitals. Site visits were conducted from January, 2014 to December, 2014. The hospital emergency response checklist, developed by the WHO, was used as an evaluation toolkit. It consists of 92 items classified as 9 key components, such as command and control, triage, and critical services. The status of each component was determined by consensus of 3 independent evaluators. The study selected 15 hospitals from different areas in Italy. Out of the 15 hospitals, 12 were considered to be at insufficients level of preparedness, only 3 were considered to have an effective level of preparedness. The average preparedness of all components were lower than the optimal level suggested by the WHO checklist. The study revealed that a large majority of Italian hospitals evaluated are not well prepared to manage potential disasters. Also, all important elements of hospital preparedness, such as the command system, surge capacity, and safety, were insufficiently implemented. Nationwide standards, guidelines and procedures are required to improve hospital disaster preparedness in Italy.

Hospital Staff Shortage after the 2011 Triple Disaster in Fukushima, Japan-An Earthquake, Tsunamis, and Nuclear Power Plant Accident: A Case of the Soso District.

PubMed

Ochi, Sae; Tsubokura, Masaharu; Kato, Shigeaki; Iwamoto, Shuichi; Ogata, Shinichi; Morita, Tomohiro; Hori, Arinobu; Oikawa, Tomoyoshi; Kikuchi, Antoku; Watanabe, Zenjiro; Kanazawa, Yukio; Kumakawa, Hiromi; Kuma, Yoshinobu; Kumakura, Tetsuo; Inomata, Yoshimitsu; Kami, Masahiro; Shineha, Ryuzaburo; Saito, Yasutoshi

2016-01-01

In 2011, Fukushima was struck by a triple disaster: an earthquake, tsunamis, and a nuclear accident. In the aftermath, there was much fear among hospital staff members about radiation exposure and many staff members failed to report to work. One objective is to measure this shortage in hospital staff and another is to compare the difference in recovery by hospital types and by categories of hospital staff. The monthly records of the number of staff members from May 2011 to September 2012 were extracted anonymously from the records of 7 local hospitals in the Soso district in Fukushima. Change in the number of staff was analyzed. Staff shortages at hospitals reached a maximum within one month after the disaster (47% reported to work). The shortage of clerks was the most severe (38% reported to work), followed by nurses (48% reported to work). The shortages remained even 18 months after the disaster. After a disaster in which the damage to hospital functions surpasses the structural damage, massive support of human resources in the acute phase and a smaller volume of support in the mid-term phase appear to be required, particularly for non-medical staff.

Hospital Staff Shortage after the 2011 Triple Disaster in Fukushima, Japan-An Earthquake, Tsunamis, and Nuclear Power Plant Accident: A Case of the Soso District

PubMed Central

Ochi, Sae; Tsubokura, Masaharu; Kato, Shigeaki; Iwamoto, Shuichi; Ogata, Shinichi; Morita, Tomohiro; Hori, Arinobu; Oikawa, Tomoyoshi; Kikuchi, Antoku; Watanabe, Zenjiro; Kanazawa, Yukio; Kumakawa, Hiromi; Kuma, Yoshinobu; Kumakura, Tetsuo; Inomata, Yoshimitsu; Kami, Masahiro; Shineha, Ryuzaburo; Saito, Yasutoshi

2016-01-01

Introduction In 2011, Fukushima was struck by a triple disaster: an earthquake, tsunamis, and a nuclear accident. In the aftermath, there was much fear among hospital staff members about radiation exposure and many staff members failed to report to work. Objectives One objective is to measure this shortage in hospital staff and another is to compare the difference in recovery by hospital types and by categories of hospital staff. Design The monthly records of the number of staff members from May 2011 to September 2012 were extracted anonymously from the records of 7 local hospitals in the Soso district in Fukushima. Change in the number of staff was analyzed. Results Staff shortages at hospitals reached a maximum within one month after the disaster (47% reported to work). The shortage of clerks was the most severe (38% reported to work), followed by nurses (48% reported to work). The shortages remained even 18 months after the disaster. Conclusion After a disaster in which the damage to hospital functions surpasses the structural damage, massive support of human resources in the acute phase and a smaller volume of support in the mid-term phase appear to be required, particularly for non-medical staff. PMID:27788170

Medical Support for Aircraft Disaster Search and Recovery Operations at Sea: the RSN Experience.

PubMed

Teo, Kok Ann Colin; Chong, Tse Feng Gabriel; Liow, Min Han Lincoln; Tang, Kong Choong

2016-06-01

The maritime environment presents a unique set of challenges to search and recovery (SAR) operations. There is a paucity of information available to guide provision of medical support for SAR operations for aircraft disasters at sea. The Republic of Singapore Navy (RSN) took part in two such SAR operations in 2014 which showcased the value of a military organization in these operations. Key considerations in medical support for similar operations include the resultant casualty profile and challenges specific to the maritime environment, such as large distances of area of operations from land, variable sea states, and space limitations. Medical support planning can be approached using well-established disaster management life cycle phases of preparedness, mitigation, response, and recovery, which all are described in detail. This includes key areas of dedicated training and exercises, force protection, availability of air assets and chamber support, psychological care, and the forensic handling of human remains. Relevant lessons learned by RSN from the Air Asia QZ8501 search operation are also included in the description of these key areas. Teo KAC , Chong TFG , Liow MHL , Tang KC . Medical support for aircraft disaster search and recovery operations at sea: the RSN experience. Prehosp Disaster Med. 2016; 31(3):294-299.

Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology.

PubMed

Feldman, Aaron W; Romesberg, Floyd E

2018-02-20

The information available to any organism is encoded in a four nucleotide, two base pair genetic code. Since its earliest days, the field of synthetic biology has endeavored to impart organisms with novel attributes and functions, and perhaps the most fundamental approach to this goal is the creation of a fifth and sixth nucleotide that pair to form a third, unnatural base pair (UBP) and thus allow for the storage and retrieval of increased information. Achieving this goal, by definition, requires synthetic chemistry to create unnatural nucleotides and a medicinal chemistry-like approach to guide their optimization. With this perspective, almost 20 years ago we began designing unnatural nucleotides with the ultimate goal of developing UBPs that function in vivo, and thus serve as the foundation of semi-synthetic organisms (SSOs) capable of storing and retrieving increased information. From the beginning, our efforts focused on the development of nucleotides that bear predominantly hydrophobic nucleobases and thus that pair not based on the complementary hydrogen bonds that are so prominent among the natural base pairs but rather via hydrophobic and packing interactions. It was envisioned that such a pairing mechanism would provide a basal level of selectivity against pairing with natural nucleotides, which we expected would be the greatest challenge; however, this choice mandated starting with analogs that have little or no homology to their natural counterparts and that, perhaps not surprisingly, performed poorly. Progress toward their optimization was driven by the construction of structure-activity relationships, initially from in vitro steady-state kinetic analysis, then later from pre-steady-state and PCR-based assays, and ultimately from performance in vivo, with the results augmented three times with screens that explored combinations of the unnatural nucleotides that were too numerous to fully characterize individually. The structure-activity relationship data identified multiple features required by the UBP, and perhaps most prominent among them was a substituent ortho to the glycosidic linkage that is capable of both hydrophobic packing and hydrogen bonding, and nucleobases that stably stack with flanking natural nucleobases in lieu of the potentially more stabilizing stacking interactions afforded by cross strand intercalation. Most importantly, after the examination of hundreds of unnatural nucleotides and thousands of candidate UBPs, the efforts ultimately resulted in the identification of a family of UBPs that are well recognized by DNA polymerases when incorporated into DNA and that have been used to create SSOs that store and retrieve increased information. In addition to achieving a longstanding goal of synthetic biology, the results have important implications for our understanding of both the molecules and forces that can underlie biological processes, so long considered the purview of molecules benefiting from eons of evolution, and highlight the promise of applying the approaches and methodologies of synthetic and medical chemistry in the pursuit of synthetic biology.

Earth Observations from the International Space Station: Benefits for Humanity

NASA Technical Reports Server (NTRS)

Stefanov, William L.

2015-01-01

The International Space Station (ISS) is a unique terrestrial remote sensing platform for observation of the Earth's land surface, oceans, and atmosphere. Unlike automated remote-sensing platforms it has a human crew; is equipped with both internal and externally-mounted active and passive remote sensing instruments; and has an inclined, low-Earth orbit that provides variable views and lighting (day and night) over 95 percent of the inhabited surface of the Earth. As such, it provides a useful complement to autonomous, sun-synchronous sensor systems in higher altitude polar orbits. Beginning in May 2012, NASA ISS sensor systems have been available to respond to requests for data through the International Charter, Space and Major Disasters, also known as the "International Disaster Charter" or IDC. Data from digital handheld cameras, multispectral, and hyperspectral imaging systems has been acquired in response to IDC activations and delivered to requesting agencies through the United States Geological Survey. The characteristics of the ISS for Earth observation will be presented, including past, current, and planned NASA, International Partner, and commercial remote sensing systems. The role and capabilities of the ISS for humanitarian benefit, specifically collection of remotely sensed disaster response data, will be discussed.

The Acquisition, Production and Dissemination of Geospatial Data for Emergency Management and Preservation of Cultural Heritage

NASA Astrophysics Data System (ADS)

Santoro, E.

2017-05-01

The crisis management of a disaster, whether caused naturally or by human action, requires a thorough knowledge of the territory involved, with regard to both its terrain and its developed areas. Therefore, it is essential that the National Mapping and Cadastral Agencies (NMCAs) and all other public and scientific institutions responsible for the production of geospatial information closely co-operate in making their data in that field available. This crucial sharing of geographic information is a top-level priority, not only in a disaster emergency situation, but also for effective urban and environmental planning and Cultural Heritage protection and preservation. Geospatial data-sharing, responding to the needs of all institutions involved in disaster surveying operations, is fundamental, as a priority, to the task of avoiding loss of human lives. However, no less important is the acquisition, dissemination and use of this data, in addition to direct, "in-the-field" operations of specialists in geomatics, in order to preserve the Cultural Heritage located in the crisis area. It is in this context that an NMCA such as the Italian Military Geographic Institute (IGMI) plays a key role.

Rehabilitation of vulnerable groups in emergencies and disasters: A systematic review

PubMed Central

Sheikhbardsiri, Hojjat; Yarmohammadian, Mohammad H.; Rezaei, Fatemeh; Maracy, Mohammad Reza

2017-01-01

BACKGROUND: Natural and man-made disasters, especially those occurring in large scales not only result in human mortality, but also cause physical, psychological, and social disabilities. Providing effective rehabilitation services in time can decrease the frequency of such disabilities. The aim of the current study was to perform a systematic review related to rehabilitation of vulnerable groups in emergencies and disasters. METHODS: The systematic review was conducted according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. The key words “recovery”, “rehabilitation”, “reconstruction”, “transformation”, “transition”, “emergency”, “disaster”, “crisis”, “hazard”, “catastrophe”, “tragedy”, “mass casualty incident”, “women”, “female”, “children”, “pediatric”, “disable”, “handicap”, “elder”, “old” and “vulnerable” were used in combination with Boolean operators OR and AND. ISI Web of Science, PubMed, Scopus, Science Direct, Ovid, ProQuest, Wiley, Google Scholar were searched. RESULTS: In this study a total of 11 928 articles were considered and 25 articles were selected for final review of rehabilitation of vulnerable groups based on the objective of this study. Twenty-five studies including six qualitative, sixteen cross-sectional and three randomized controlled trials were reviewed for rehabilitation of vulnerable groups in emergencies and disasters. Out of the selected papers, 23 were studied based on rehabilitation after natural disasters and the remaining were man-made disasters. Most types of rehabilitation were physical, social, psychological and economic. CONCLUSION: The review of the papers showed different programs of physical, physiological, economic and social rehabilitations for vulnerable groups after emergencies and disasters. It may help health field managers better implement standard rehabilitation activities for vulnerable groups. PMID:29123602

IPCC Special Report on Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation

NASA Astrophysics Data System (ADS)

Field, C. B.; Stocker, T. F.; Barros, V. R.; Qin, D.; Ebi, K. L.; Midgley, P. M.

2011-12-01

The Summary for Policy Makers of the IPCC Special Report on Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation will be approved by the world governments in November 2011. The focus of the Special Report is on climate change and its role in altering the frequency, severity, and impact of extreme events or disasters, and on the costs of both impacts and the actions taken to prepare for, respond to, and recover from extreme events and disasters. The emphasis is on understanding the factors that make people and infrastructure vulnerable to extreme events, on recent and future changes in the relationship between climate change and extremes, and on managing the risks of disasters over a wide range of spatial and temporal scales. The assessment considers a broad suite of adaptations and explores the limits to adaptation. The assessment was designed to build durable links and foundations for partnerships between the stakeholder communities focused on climate change and those focused on disaster risk reduction. The Special Report begins with material that frames the issues, followed by an assessment of the reasons that communities are vulnerable. Two chapters assess the role of past and future climate change in altering extremes and the impact of these on the physical environment and human systems. Three chapters assess available knowledge on impacts and adaptation, with separate chapters considering the literature, stakeholder relationships, and potential policy tools relevant to the local, national, and international scales. Longer-term components of adaptation to weather and climate extremes and disasters are assessed in the context of moving toward sustainability. The final chapter provides case studies that integrate themes across several chapters or are so unique that they need to be considered separately.

Multi-hazard national-level risk assessment in Africa using global approaches

NASA Astrophysics Data System (ADS)

Fraser, Stuart; Jongman, Brenden; Simpson, Alanna; Murnane, Richard

2016-04-01

In recent years Sub-Saharan Africa has been characterized by unprecedented opportunity for transformation and sustained growth. However, natural disasters such as droughts, floods, cyclones, earthquakes, landslides, volcanic eruptions and extreme temperatures cause significant economic and human losses, and major development challenges. Quantitative disaster risk assessments are an important basis for governments to understand disaster risk in their country, and to develop effective risk management and risk financing solutions. However, the data-scarce nature of many Sub-Saharan African countries as well as a lack of financing for risk assessments has long prevented detailed analytics. Recent advances in globally applicable disaster risk modelling practices and data availability offer new opportunities. In December 2013 the European Union approved a € 60 million contribution to support the development of an analytical basis for risk financing and to accelerate the effective implementation of a comprehensive disaster risk reduction. The World Bank's Global Facility for Disaster Reduction and Recovery (GFDRR) was selected as the implementing partner of the Program for Result Area 5: the "Africa Disaster Risk Assessment and Financing Program." As part of this effort, the GFDRR is overseeing the production of national-level multi-hazard risk profiles for a range of countries in Sub-Saharan Africa, using a combination of national and global datasets and state-of-the-art hazard and risk assessment methodologies. In this presentation, we will highlight the analytical approach behind these assessments, and show results for the first five countries for which the assessment has been completed (Kenya, Uganda, Senegal, Niger and Ethiopia). The presentation will also demonstrate the visualization of the risk assessments into understandable and visually attractive risk profile documents.

NCSE's 13th National Conference on Disasters and Environment: Science, Preparedness and Resilience, Post Conference Follow-up Activities and Dissemination

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saundry, Peter; Kossak, Shelley

The National Council for Science and the Environment (NCSE) received $15,000 from the US Department of Energy to support post-conference activities of the 13th National Conference on the theme of Disasters and the Environment: Science, Preparedness and Resilience, held on January 15-17, 2013 at the Ronald Reagan Building and International Trade Center in Washington, DC. Over 1,000 participants from the scientific, emergency response, policy, conservation, and business communities, as well as federal and local government officials, and international entities attended the event. The conference developed actionable outcomes that constructively advance the science behind decision-making on environmental disasters, with an intendedmore » result of more prepared and resilient communities in light of a changing climate. Disasters and Environment topic was addressed through six organizing themes: Cascading Disasters; Intersection of the Built and Natural Environments; Disasters as Mechanisms of Ecosystem Change; Rethinking Recovery and Expanding the Vision of Mitigation; Human Behavior and its Consequences; and "No Regrets" Resilience. The program featured eight plenary sessions, 24 symposia and 23 breakout workshops and addressed pivotal issues surrounding disasters and environment including lifeline services, the energy, climate, hazard nexus, grid collapse, community vulnerability, and natural resource management. Sessions, symposia and workshops were conducted by over 200 distinguished thought leaders, scientists, government officials, policy experts and international speakers throughout the three day event. Following the conference, NCSE prepared a set of recommendations and results from the workshops and disseminated the results to universities, organizations and agencies, the business community. NCSE’s national dissemination involved organized several targeted trips and meetings to disseminate significant findings to key stakeholder groups.« less

Response to the 2011 Great East Japan Earthquake and Tsunami disaster.

PubMed

Koshimura, Shunichi; Shuto, Nobuo

2015-10-28

We revisited the lessons of the 2011 Great East Japan Earthquake Tsunami disaster specifically on the response and impact, and discussed the paradigm shift of Japan's tsunami disaster management policies and the perspectives for reconstruction. Revisiting the modern histories of Tohoku tsunami disasters and pre-2011 tsunami countermeasures, we clarified how Japan's coastal communities have prepared for tsunamis. The discussion mainly focuses on structural measures such as seawalls and breakwaters and non-structural measures of hazard map and evacuation. The responses to the 2011 event are discussed specifically on the tsunami warning system and efforts to identify the tsunami impacts. The nation-wide post-tsunami survey results shed light on the mechanisms of structural destruction, tsunami loads and structural vulnerability to inform structural rehabilitation measures and land-use planning. Remarkable paradigm shifts in designing coastal protection and disaster mitigation measures were introduced, leading with a new concept of potential tsunami levels: Prevention (Level 1) and Mitigation (Level 2) levels according to the level of 'protection'. The seawall is designed with reference to Level 1 tsunami scenario, while comprehensive disaster management measures should refer to Level 2 tsunami for protection of human lives and reducing potential losses and damage. Throughout the case study in Sendai city, the proposed reconstruction plan was evaluated from the tsunami engineering point of view to discuss how the post 2011 paradigm was implemented in coastal communities for future disaster mitigation. The analysis revealed that Sendai city's multiple protection measures for Level 2 tsunami will contribute to a substantial reduction of the tsunami inundation zone and potential losses, combined with an effective tsunami evacuation plan. © 2015 The Author(s).

Role of ICSU Rolac on Disaster Risk Management Link to Food Production Prof. Manuel Limonta Director of ICSU Rolac

NASA Astrophysics Data System (ADS)

Limonta, M. D.

2013-05-01

The 85% of people exposed to earthquakes, cyclones, floods and droughts live in developing countries. The enormous cost of disasters threatens the achievement of the Millennium Development Goals, especially the first objective: to reduce poverty half by 2015. The Disaster risk reduction is vital to secure one of the most fundamental human rights. The right to be free from hunger. Each year, Latin America and the Caribbean countries are affected by natural disasters, such as droughts, floods, hurricanes, landslides, volcanic eruptions, which are added to epidemics and socio-economic crises. These events result in loss of lives, property and livelihoods, and therefore undermine the food security and nutritional status of vulnerable populations. While in the region geophysical disasters caused most deaths and economic lost. The result has been lives lost in Haiti and the destruction of valuable infrastructure in Chile. Bearing mind also that the largest number of disasters were caused by climatic impacts. The 2010 hurricane season in the Atlantic was the most active since 2005 and experienced its worst rainy season in the last 50 years in Central America. ICSU, ICSU ROLAC, DISASTERS AND FOOD SECURITY ICSU ICSU's mission is to strengthen international science for the benefit of society. To do this, ICSU mobilizes the knowledge and resources of the international science community to: Identify and address major issues of Importance to science and society. Facilitate interaction amongst scientists across all disciplines and from all countries. Promote the participation of all scientists-regardless of race, citizenship, language, political stance, or gender-in the international scientific endeavour. ICSU ROLAC The mission of the ICSU Regional Office for Latin America and the Caribbean is to ensure that the Regional Priorities are reflected in the ICSU Strategic Plan to develop sound regional and scientific programs. The ICSU ROLAC scientific priority areas are: Biodiversity, Natural Hazards, Sustainable energy, Mathematics education. DISASTERS AND FOOD SECURITY The problem of food security is multifactorial, however, there is no doubt that disasters are a major cause of food insecurity therefore the focusing of the work of ICSU on the topic of disaster, should include food security with the emphasis it deserves as one of the major consequences of these major events. Our ICSU LAC Region must address the issue of food security related to disasters as an important aspect of the program of work disasters in the region. When we analyze the events and activities of our organization work, we appreciate that the topic Regional Food Security as a result of disasters is not treated with the breadth and depth that it deserves. Given the characteristics of our region is necessary to add this new paradigm to disaster work. IN CONCLUSION It is proposed that the program of ICSU ROLAC on disasters include the issue of food security, as an important part to be treated and worked through all the channels and connections of our organization.

Sensing pH via p-cyanophenylalanine fluorescence: Application to determine peptide pKa and membrane penetration kinetics.

PubMed

Pazos, Ileana M; Ahmed, Ismail A; Berríos, Mariana I León; Gai, Feng

2015-08-15

We expand the spectroscopic utility of a well-known infrared and fluorescence probe, p-cyanophenylalanine, by showing that it can also serve as a pH sensor. This new application is based on the notion that the fluorescence quantum yield of this unnatural amino acid, when placed at or near the N-terminal end of a polypeptide, depends on the protonation status of the N-terminal amino group of the peptide. Using this pH sensor, we are able to determine the N-terminal pKa values of nine tripeptides and also the membrane penetration kinetics of a cell-penetrating peptide. Taken together, these examples demonstrate the applicability of using this unnatural amino acid fluorophore to study pH-dependent biological processes or events that accompany a pH change. Copyright © 2015 Elsevier Inc. All rights reserved.

Controllable Edge Feature Sharpening for Dental Applications

PubMed Central

2014-01-01

This paper presents a new approach to sharpen blurred edge features in scanned tooth preparation surfaces generated by structured-light scanners. It aims to efficiently enhance the edge features so that the embedded feature lines can be easily identified in dental CAD systems, and to avoid unnatural oversharpening geometry. We first separate the feature regions using graph-cut segmentation, which does not require a user-defined threshold. Then, we filter the face normal vectors to propagate the geometry from the smooth region to the feature region. In order to control the degree of the sharpness, we propose a feature distance measure which is based on normal tensor voting. Finally, the vertex positions are updated according to the modified face normal vectors. We have applied the approach to scanned tooth preparation models. The results show that the blurred edge features are enhanced without unnatural oversharpening geometry. PMID:24741376

Controllable edge feature sharpening for dental applications.

PubMed

Fan, Ran; Jin, Xiaogang

2014-01-01

This paper presents a new approach to sharpen blurred edge features in scanned tooth preparation surfaces generated by structured-light scanners. It aims to efficiently enhance the edge features so that the embedded feature lines can be easily identified in dental CAD systems, and to avoid unnatural oversharpening geometry. We first separate the feature regions using graph-cut segmentation, which does not require a user-defined threshold. Then, we filter the face normal vectors to propagate the geometry from the smooth region to the feature region. In order to control the degree of the sharpness, we propose a feature distance measure which is based on normal tensor voting. Finally, the vertex positions are updated according to the modified face normal vectors. We have applied the approach to scanned tooth preparation models. The results show that the blurred edge features are enhanced without unnatural oversharpening geometry.

Recent advances in racemic protein crystallography.

PubMed

Yan, Bingjia; Ye, Linzhi; Xu, Weiliang; Liu, Lei

2017-09-15

Solution of the three-dimensional structures of proteins is a critical step in deciphering the molecular mechanisms of their bioactivities. Among the many approaches for obtaining protein crystals, racemic protein crystallography has been developed as a unique method to solve the structures of an increasing number of proteins. Exploiting unnatural protein enantiomers in crystallization and resolution, racemic protein crystallography manifests two major advantages that are 1) to increase the success rate of protein crystallization, and 2) to obviate the phase problem in X-ray diffraction. The requirement of unnatural protein enantiomers in racemic protein crystallography necessitates chemical protein synthesis, which is hitherto accomplished through solid phase peptide synthesis and chemical ligation reactions. This review highlights the fundamental ideas of racemic protein crystallography and surveys the harvests in the field of racemic protein crystallography over the last five years from early 2012 to late 2016. Copyright © 2017. Published by Elsevier Ltd.

Genetic incorporation of recycled unnatural amino acids.

PubMed

Ko, Wooseok; Kim, Sanggil; Jo, Kyubong; Lee, Hyun Soo

2016-02-01

The genetic incorporation of unnatural amino acids (UAAs) into proteins has been a useful tool for protein engineering. However, most UAAs are expensive, and the method requires a high concentration of UAAs, which has been a drawback of the technology, especially for large-scale applications. To address this problem, a method to recycle cultured UAAs was developed. The method is based on recycling a culture medium containing the UAA, in which some of essential nutrients were resupplemented after each culture cycle, and induction of protein expression was controlled with glucose. Under optimal conditions, five UAAs were recycled for up to seven rounds of expression without a decrease in expression level, cell density, or incorporation fidelity. This method can generally be applied to other UAAs; therefore, it is useful for reducing the cost of UAAs for genetic incorporation and helpful for expanding the use of the technology to industrial applications.

Impact of the Great East Japan Earthquake on Hotel Industry in Pacific Tohoku Prefectures ---From Spatio-Temporal Dependence of Hotel Availability---

NASA Astrophysics Data System (ADS)

Sato, A.

This paper investigates the impact of the Great Japan Earthquake(and subsequent tsunami turmoil) on socio-economic activities by using data on hotel opportunities collected from an electronic hotel booking service. A method to estimate both primary and secondary regional effects of a natural disaster on human behavior is proposed. It is confirmed that temporal variation in the regional share of available hotels before and after a natural disaster may be an indicator to measure the socio-economic impact at each district.

Policy development in disaster preparedness and management: lessons learned from the January 2001 earthquake in Gujarat, India.

PubMed

Bremer, Rannveig

2003-01-01

During the last decades, several humanitarian emergencies have occurred, with an increasing number of humanitarian organizations taking part in providing assistance. However, need assessments, medical intelligence, and coordination of the aid often are sparse, resulting in the provision of ineffective and expensive assistance. When an earthquake with the strength of 7.7 on the Richter scale struck the state of Gujarat, India, during the early morning on 26 January 2001, nearly 20,000 persons were killed, nearly 170,000 were injured, and 600,000 were rendered homeless. This study identifies how assigned indicators to measure the level of health care may improve disaster preparedness and management, thus, reducing human suffering. During a two-week mission in the disaster area, the disaster relief provided to the disaster-affected population of Gujarat was evaluated. Vulnerability due to climate, geography, culture, religion, gender, politics, and economy, as each affected the outcome, was studied. By assigning indicators to the eight ELEMENTS of the Primary Health Care System as advocated by the World Health Organization (WHO), the level of public health and healthcare services were estimated, an evaluation of the impact of the disaster was conducted, and possible methods for improving disaster management are suggested. Representatives of the major relief organizations involved were interviewed on their relief policies. Strategies to improve disaster relief, such as policy development in the different aspects of public health/primary health care, were sought. Evaluation of the pre-event status of the affected society revealed a complex situation in a vulnerable society with substantial deficiencies in the existing health system that added to the severity of the disaster. Most of the civilian hospitals had collapsed, and army field hospitals provided medical care to most of the patients under primitive conditions using tents. When the foreign field hospitals arrived five to seven days after the earthquake, most of the casualties requiring surgical intervention already had been operated on. Relief provided to the disaster victims had reduced quality for the following reasons: (1) proper public health indicators had not yet been developed; (2) efficient coordination was lacking, (3) insufficient, overestimated, or partly irrelevant relief was provided; (4) relief was delayed because of bureaucracy; and (5) policies on the delivery of disaster relief had not been developed. To optimize the effectiveness of limited resources, disaster preparedness and the provision of feasible and necessary aid is of utmost importance. An appropriate, rapid, crisis intervention could be achieved by continual surveillance of the world's situation by a Relief Coordination Center. A panel of experts could evaluate and coordinate the international disaster responses and make use of stored emergency material and emergency teams. A successful disaster response will depend on accurate and relevant medical intelligence and socio-geographical mapping in advance of, during, and after the event(s) causing the disaster. More effective and feasible equipment coordinated with the relief provided by the rest of the world is necessary. If policies and agreements are developed as part of disaster preparedness, on international, bilateral, and national levels, disaster relief may be more relevant, less chaotic, and easier to estimate, thus, bringing improved relief to the disaster victims.

Post-traumatic stress disorder in disaster survivors.

PubMed

North, C S; Smith, E M

1990-12-01

In spite of the difficulties inherent in the study of traumatic stress in disaster victims, the benefit of obtaining more knowledge on the subject is potentially great, especially considering the numbers of individuals affected. Recent estimates of the frequency of world-wide traumatic events have determined that almost two million households annually experience damages and/or injuries from fire, floods, hurricanes, tornadoes, and earthquakes alone. The population that is at risk is expected to grow exponentially with our expanding technology, making it even more vital to acquire knowledge to help the growing number of future disaster victims. Additionally, disaster research can contribute to a better understanding of PTSD and human coping processes that can be generalized to more ordinary stress situations. In the meantime, survivors of major catastrophes who experience acute symptoms of PTSD such as insomnia, nightmares, and jumpiness should be observed for nonresolution of symptoms over time, especially if there is a premorbid history of psychopathology or character problems. Otherwise, survivors may benefit from reassurance that PTSD symptoms are common in the short-term postdisaster period and that they can usually be expected to dissipate with time.

The Bhopal disaster and its aftermath: a review.

PubMed

Broughton, Edward

2005-05-10

On December 3 1984, more than 40 tons of methyl isocyanate gas leaked from a pesticide plant in Bhopal, India, immediately killing at least 3,800 people and causing significant morbidity and premature death for many thousands more. The company involved in what became the worst industrial accident in history immediately tried to dissociate itself from legal responsibility. Eventually it reached a settlement with the Indian Government through mediation of that country's Supreme Court and accepted moral responsibility. It paid $470 million in compensation, a relatively small amount of based on significant underestimations of the long-term health consequences of exposure and the number of people exposed. The disaster indicated a need for enforceable international standards for environmental safety, preventative strategies to avoid similar accidents and industrial disaster preparedness. Since the disaster, India has experienced rapid industrialization. While some positive changes in government policy and behavior of a few industries have taken place, major threats to the environment from rapid and poorly regulated industrial growth remain. Widespread environmental degradation with significant adverse human health consequences continues to occur throughout India.

Post Disaster Governance, Complexity and Network Theory: Evidence from Aceh, Indonesia After the Indian Ocean Tsunami 2004.

PubMed

Lassa, Jonatan A

2015-07-01

This research aims to understand the organizational network typology of large--scale disaster intervention in developing countries and to understand the complexity of post--disaster intervention, through the use of network theory based on empirical data from post--tsunami reconstruction in Aceh, Indonesia, during 2005/-2007. The findings suggest that the ' degrees of separation' (or network diameter) between any two organizations in the field is 5, thus reflecting 'small- world' realities and therefore making no significant difference with the real human networks, as found in previous experiments. There are also significant loops in the network reflecting the fact that some actors tend to not cooperate, which challenges post- disaster coordination. The findings show the landscape of humanitarian actors is not randomly distributed. Many actors were connected to each other through certain hubs, while hundreds of actors make 'scattered' single 'principal--client' links. The paper concludes that by understanding the distribution of degree, centrality, 'degrees of separation' and visualization of the network, authorities can improve their understanding of the realities of coordination, from macro to micro scales.

Congestion detection of pedestrians using the velocity entropy: A case study of Love Parade 2010 disaster

NASA Astrophysics Data System (ADS)

Huang, Lida; Chen, Tao; Wang, Yan; Yuan, Hongyong

2015-12-01

Gatherings of large human crowds often result in crowd disasters such as the Love Parade Disaster in Duisburg, Germany on July 24, 2010. To avoid these tragedies, video surveillance and early warning are becoming more and more significant. In this paper, the velocity entropy is first defined as the criterion for congestion detection, which represents the motion magnitude distribution and the motion direction distribution simultaneously. Then the detection method is verified by the simulation data based on AnyLogic software. To test the generalization performance of this method, video recordings of a real-world case, the Love Parade disaster, are also used in the experiments. The velocity histograms of the foreground object in the videos are extracted by the Gaussian Mixture Model (GMM) and optical flow computation. With a sequential change-point detection algorithm, the velocity entropy can be applied to detect congestions of the Love Parade festival. It turned out that without recognizing and tracking individual pedestrian, our method can detect abnormal crowd behaviors in real-time.

Application of Modern Tools and Techniques for Mine Safety & Disaster Management

NASA Astrophysics Data System (ADS)

Kumar, Dheeraj

2016-04-01

The implementation of novel systems and adoption of improvised equipment in mines help mining companies in two important ways: enhanced mine productivity and improved worker safety. There is a substantial need for adoption of state-of-the-art automation technologies in the mines to ensure the safety and to protect health of mine workers. With the advent of new autonomous equipment used in the mine, the inefficiencies are reduced by limiting human inconsistencies and error. The desired increase in productivity at a mine can sometimes be achieved by changing only a few simple variables. Significant developments have been made in the areas of surface and underground communication, robotics, smart sensors, tracking systems, mine gas monitoring systems and ground movements etc. Advancement in information technology in the form of internet, GIS, remote sensing, satellite communication, etc. have proved to be important tools for hazard reduction and disaster management. This paper is mainly focused on issues pertaining to mine safety and disaster management and some of the recent innovations in the mine automations that could be deployed in mines for safe mining operations and for avoiding any unforeseen mine disaster.

Natural disasters and population mobility in Bangladesh.

PubMed

Gray, Clark L; Mueller, Valerie

2012-04-17

The consequences of environmental change for human migration have gained increasing attention in the context of climate change and recent large-scale natural disasters, but as yet relatively few large-scale and quantitative studies have addressed this issue. We investigate the consequences of climate-related natural disasters for long-term population mobility in rural Bangladesh, a region particularly vulnerable to environmental change, using longitudinal survey data from 1,700 households spanning a 15-y period. Multivariate event history models are used to estimate the effects of flooding and crop failures on local population mobility and long-distance migration while controlling for a large set of potential confounders at various scales. The results indicate that flooding has modest effects on mobility that are most visible at moderate intensities and for women and the poor. However, crop failures unrelated to flooding have strong effects on mobility in which households that are not directly affected but live in severely affected areas are the most likely to move. These results point toward an alternate paradigm of disaster-induced mobility that recognizes the significant barriers to migration for vulnerable households as well their substantial local adaptive capacity.

Human Rights in Social Science Textbooks: Cross-National Analyses, 1970-2008

ERIC Educational Resources Information Center

Meyer, John W.; Bromley, Patricia; Ramirez, Francisco O.

2010-01-01

In reaction to the disasters of the first half the 20th century and World War II, a dramatic world movement arose emphasizing the human rights of persons in global society. The contrast--celebrated in international treaties, intergovernmental and nongovernmental organizations, and much cultural discourse--was with narrower world emphases on the…

Globalization of flora: inviting worldwide ecosystem disaster.

Treesearch

Andrew B. Carey

2002-01-01

Meeting the needs of expanding human populations has changed land use worldwide and presented a biodiversity crisis. Emerging related concerns are threats to native species from homogenization of world flora and the spread of exotic species by human activities (Soule 1990, United States Congress, Office of Technology Assessment 1993, Wilcove and others 1998, Soule and...

Intriguing Connections Between Economic Geology, the Environment, Human Health, and Disasters: Observations from my Career(s) in Transdisciplinary Science

NASA Astrophysics Data System (ADS)

Plumlee, G. S.

2015-12-01

I have been fortunate to be able to follow a varied career path from economic geology, to environmental geochemistry, to geochemistry and human health, to environmental disasters. I have been privileged to collaborate with many exceptional scientists from across and well beyond the earth sciences (e.g., public heath, engineering, economics, emergency response, microbiology). Much of this transdisciplinary work has intriguing links back to economic geology/geochemistry. Geological characteristics of different ore deposit types predictably influence the environmental and health impacts of mining, and so can help anticipate and prevent adverse impacts before they occur. Geologic maps showing potential for natural occurrences of asbestos or erionite are analogous to permissive tract maps used for mineral-resource assessments, and can be correlated with epidemiological data to help understand whether living on or near such rocks poses a risk for developing asbestos-related diseases. Mineral particles that are taken up by the human body along inhalation or incidental ingestion exposure routes are "weathered" by reactions with diverse body fluids that differ greatly in composition between and along the different exposure routes. These in vivo chemical reactions (e.g., dissolution, alteration, metal complexation, oxidation/reduction, reprecipitation) are in ways analogous to processes of ore deposit formation and weathering, and some can be shown (in collaboration with toxicologists) to play a role in toxicity. Concepts of ore petrography and paragenesis can be applied to interpret (in collaboration with pathologists) the origin, physiological implications, and toxicity effects of mineral matter in human tissue samples obtained by biopsy, transplant or autopsy. Some disaster materials can originate from mining- or mineral-processing sources, and methods originally developed to study ore deposits or mining-environmental issues can also be applied to understand many disaster materials. These examples illustrate an appropriate core role for earth scientists in transdisciplinary research: applying our expertise and toolkits to help understand topics well beyond earth sciences, but doing so in collaboration with experts from disciplines that traditionally examine those topics.

Analyzing and sense making of human factors in the Malaysian radiation and nuclear emergency planning framework

NASA Astrophysics Data System (ADS)

Hamid, A. H. A.; Rozan, M. Z. A.; Deris, S.; Ibrahim, R.; Abdullah, W. S. W.; Rahman, A. A.; Yunus, M. N. M.

2016-01-01

The evolution of current Radiation and Nuclear Emergency Planning Framework (RANEPF) simulator emphasizes on the human factors to be analyzed and interpreted according to the stakeholder's tacit and explicit knowledge. These human factor criteria are analyzed and interpreted according to the "sense making theory" and Disaster Emergency Response Management Information System (DERMIS) design premises. These criteria are corroborated by the statistical criteria. In recent findings, there were no differences of distributions among the stakeholders according to gender and organizational expertise. These criteria are incrementally accepted and agreed the research elements indicated in the respective emergency planning frameworks and simulator (i.e. 78.18 to 84.32, p-value <0.05). This paper suggested these human factors criteria in the associated analyses and theoretical perspectives to be further acomodated in the future simulator development. This development is in conjunction with the proposed hypothesis building of the process factors and responses diagram. We proposed that future work which implies the additional functionality of the simulator, as strategized, condensed and concise, comprehensive public disaster preparedness and intervention guidelines, to be a useful and efficient computer simulation.

Oxidative diversification of amino acids and peptides by small-molecule iron catalysis.

PubMed

Osberger, Thomas J; Rogness, Donald C; Kohrt, Jeffrey T; Stepan, Antonia F; White, M Christina

2016-09-08

Secondary metabolites synthesized by non-ribosomal peptide synthetases display diverse and complex topologies and possess a range of biological activities. Much of this diversity derives from a synthetic strategy that entails pre- and post-assembly oxidation of both the chiral amino acid building blocks and the assembled peptide scaffolds. The vancomycin biosynthetic pathway is an excellent example of the range of oxidative transformations that can be performed by the iron-containing enzymes involved in its biosynthesis. However, because of the challenges associated with using such oxidative enzymes to carry out chemical transformations in vitro, chemical syntheses guided by these principles have not been fully realized in the laboratory. Here we report that two small-molecule iron catalysts are capable of facilitating the targeted C-H oxidative modification of amino acids and peptides with preservation of α-centre chirality. Oxidation of proline to 5-hydroxyproline furnishes a versatile intermediate that can be transformed to rigid arylated derivatives or flexible linear carboxylic acids, alcohols, olefins and amines in both monomer and peptide settings. The value of this C-H oxidation strategy is demonstrated in its capacity for generating diversity: four 'chiral pool' amino acids are transformed to twenty-one chiral unnatural amino acids representing seven distinct functional group arrays; late-stage C-H functionalizations of a single proline-containing tripeptide furnish eight tripeptides, each having different unnatural amino acids. Additionally, a macrocyclic peptide containing a proline turn element is transformed via late-stage C-H oxidation to one containing a linear unnatural amino acid.

Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA.

PubMed

Guza, Rebecca; Kotandeniya, Delshanee; Murphy, Kristopher; Dissanayake, Thakshila; Lin, Chen; Giambasu, George Madalin; Lad, Rahul R; Wojciechowski, Filip; Amin, Shantu; Sturla, Shana J; Hudson, Robert H E; York, Darrin M; Jankowiak, Ryszard; Jones, Roger; Tretyakova, Natalia Y

2011-05-01

Endogenous 5-methylcytosine ((Me)C) residues are found at all CG dinucleotides of the p53 tumor suppressor gene, including the mutational 'hotspots' for smoking induced lung cancer. (Me)C enhances the reactivity of its base paired guanine towards carcinogenic diolepoxide metabolites of polycyclic aromatic hydrocarbons (PAH) present in cigarette smoke. In the present study, the structural basis for these effects was investigated using a series of unnatural nucleoside analogs and a representative PAH diolepoxide, benzo[a]pyrene diolepoxide (BPDE). Synthetic DNA duplexes derived from a frequently mutated region of the p53 gene (5'-CCCGGCACCC GC[(15)N(3),(13)C(1)-G]TCCGCG-3', + strand) were prepared containing [(15)N(3), (13)C(1)]-guanine opposite unsubstituted cytosine, (Me)C, abasic site, or unnatural nucleobase analogs. Following BPDE treatment and hydrolysis of the modified DNA to 2'-deoxynucleosides, N(2)-BPDE-dG adducts formed at the [(15)N(3), (13)C(1)]-labeled guanine and elsewhere in the sequence were quantified by mass spectrometry. We found that C-5 alkylcytosines and related structural analogs specifically enhance the reactivity of the base paired guanine towards BPDE and modify the diastereomeric composition of N(2)-BPDE-dG adducts. Fluorescence and molecular docking studies revealed that 5-alkylcytosines and unnatural nucleobase analogs with extended aromatic systems facilitate the formation of intercalative BPDE-DNA complexes, placing BPDE in a favorable orientation for nucleophilic attack by the N(2) position of guanine. © The Author(s) 2011. Published by Oxford University Press.

Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA

PubMed Central

Guza, Rebecca; Kotandeniya, Delshanee; Murphy, Kristopher; Dissanayake, Thakshila; Lin, Chen; Giambasu, George Madalin; Lad, Rahul R.; Wojciechowski, Filip; Amin, Shantu; Sturla, Shana J.; Hudson, Robert H.E.; York, Darrin M.; Jankowiak, Ryszard; Jones, Roger; Tretyakova, Natalia Y.

2011-01-01

Endogenous 5-methylcytosine (MeC) residues are found at all CG dinucleotides of the p53 tumor suppressor gene, including the mutational ‘hotspots’ for smoking induced lung cancer. MeC enhances the reactivity of its base paired guanine towards carcinogenic diolepoxide metabolites of polycyclic aromatic hydrocarbons (PAH) present in cigarette smoke. In the present study, the structural basis for these effects was investigated using a series of unnatural nucleoside analogs and a representative PAH diolepoxide, benzo[a]pyrene diolepoxide (BPDE). Synthetic DNA duplexes derived from a frequently mutated region of the p53 gene (5′-CCCGGCACCC GC[15N3,13C1-G]TCCGCG-3′, + strand) were prepared containing [15N3, 13C1]-guanine opposite unsubstituted cytosine, MeC, abasic site, or unnatural nucleobase analogs. Following BPDE treatment and hydrolysis of the modified DNA to 2′-deoxynucleosides, N2-BPDE-dG adducts formed at the [15N3, 13C1]-labeled guanine and elsewhere in the sequence were quantified by mass spectrometry. We found that C-5 alkylcytosines and related structural analogs specifically enhance the reactivity of the base paired guanine towards BPDE and modify the diastereomeric composition of N2-BPDE-dG adducts. Fluorescence and molecular docking studies revealed that 5-alkylcytosines and unnatural nucleobase analogs with extended aromatic systems facilitate the formation of intercalative BPDE–DNA complexes, placing BPDE in a favorable orientation for nucleophilic attack by the N2 position of guanine. PMID:21245046

Introduction of unnatural amino acids into chalcone isomerase.

PubMed

Bednar, R A; McCaffrey, C; Shan, K

1991-01-01

The active site cysteine residue of chalcone isomerase was rapidly and selectively modified under denaturing conditions with a variety of electrophilic reagents. These denatured and modified enzyme were renatured to produce enzyme derivatives containing a series of unnatural amino acids in the active site. Addition of methyl, ethyl, butyl, heptyl, and benzyl groups to the cysteine sulfur does not abolish catalytic activity, although the activity decreases as the steric bulk of the amino acid side-chain increases. Modification of the cysteine to introduce a charged homoglutamate or a neutral homoglutamine analogue results in retention of 22% of the catalytic activity. Addition of a methylthio group (SMe) to the cysteine residue of native chalcone isomerase preserves 85% of the catalytic activity measured with 2',4',4-trihydroxychalcone, 2',4',6',4-tetrahydroxychalcone, or 2'-hydroxy-4-methoxychalcone as substrates. The competitive inhibition constant for 4',4-dihydroxychalcone, the substrate inhibition constant for 2',4',4-trihydroxychalcone, and other steady-state kinetic parameters for the methanethiolated enzyme are very similar to those of the native enzyme. The strong binding of 4',4-dihydroxychalcone to the methanethiolated enzyme shows that there is no steric repulsion between this modified amino acid residue and the substrate analogue. This structure-activity study clearly demonstrates that the active site cysteine residue does not function as an acid-base or nucleophilic group in producing the catalysis or substrate inhibition observed with chalcone isomerase. The method presented in this paper allows for the rapid introduction of a series of unnatural amino acids into the active site as a means of probing the structure-function relationship.

Influence of side chain conformation and configuration on glycosyl donor reactivity and selectivity as illustrated by sialic acid donors epimeric at the 7-position.

PubMed

Kancharla, Pavan K; Crich, David

2013-12-18

Two N-acetyl 4O,5N-oxazolidinone-protected sialyl thioglycosides epimeric at the 7-position have been synthesized and their reactivity and stereoselectivity in glycosylation reactions have been compared. It is demonstrated that the natural 7S-donor is both more reactive and more α-selective than the unnatural 7R-isomer. The difference in reactivity is attributed to the side chain conformation and specifically to the proximity of O7 to the anomeric center. In the natural 7S-isomer, O7 is closer to the anomeric center than in its unnatural 7R-epimer and, therefore, better able to support incipient positive charge at the locus of reaction. The difference in selectivity is also attributed to the side conformation, which in the unnatural 7R-series is placed perpendicularly above the α-face of the donor and so shields it to a greater extent than in the 7S-series. These observations are consistent with earlier conclusions on the influence of the side chain conformation on reactivity and selectivity derived from conformationally locked models in the glucose and galactose series and corroborate the suggestion that those effects are predominantly stereoelectronic rather than torsional. The possible relevance of side chain conformation as a factor in the influence of glycosylation stereoselectivity by remote protecting groups and as a control element in enzymic processes for glycosidic bond formation and hydrolysis are discussed. Methods for assignment of the anomeric configuration in the sialic acid glycosides are critically surveyed.

Unnatural sudden infant death

PubMed Central

Meadow, R.

1999-01-01

AIM—To identify features to help paediatricians differentiate between natural and unnatural infant deaths.
METHOD—Clinical features of 81 children judged by criminal and family courts to have been killed by their parents were studied. Health and social service records, court documents, and records from meetings with parents, relatives, and social workers were studied.
RESULTS—Initially, 42 children had been certified as dying from sudden infant death syndrome (SIDS), and 29 were given another cause of natural death. In 24 families, more than one child died; 58died before the age of 6 months and most died in the afternoon or evening. Seventy per cent had experienced unexplained illnesses; over half were admitted to hospital within the previous month, and 15 had been discharged within 24 hours of death. The mother, father, or both were responsible for death in 43, five, and two families, respectively. Most homes were disadvantaged—no regular income, receiving income support—and mothers smoked. Half the perpetrators had a history of somatising or factitious disorder. Death was usually by smothering and 43% of children had bruises, petechiae, or blood on the face.
CONCLUSIONS—Although certain features are indicative of unnatural infant death, some are also associated with SIDS. Despite the recent reduction in numbers of infants dying suddenly, inadequacies in the assessment of their deaths exist. Until a thorough postmortem examination is combined with evaluation of the history and circumstances of death by an experienced paediatrician, most cases of covert fatal abuse will go undetected. The term SIDS requires revision or abandonment.

 PMID:10325752

Brains in the City: Neurobiological effects of urbanization

PubMed Central

Lambert, Kelly G.; Nelson, Randy J.; Jovanovic, Tanja; Cerdá, Magdalena

2016-01-01

With a majority of humans now living in cities, strategic research is necessary to elucidate the impact of this evolutionarily unfamiliar habitat on neural functions and well-being. In this review, both rodent and human models are considered in the evaluation of the changing physical and social landscapes associated with urban dwellings. Animal models assessing increased exposure to artificial physical elements characteristic of urban settings, as well as exposure to unnatural sources of light for extended durations, are reviewed. In both cases, increased biomarkers of mental illnesses such as major depression have been observed. Additionally, applied human research emphasizing the emotional impact of environmental threats associated with urban habitats is considered. Subjects evaluated in an inner-city hospital reveal the impact of combined specific genetic vulnerabilities and heightened stress responses in the expression of posttraumatic stress disorder. Finally, algorithm-based models of cities have been developed utilizing population-level analyses to identify risk factors for psychiatric illness. Although complex, the use of multiple research approaches, as described herein, results in an enhanced understanding of urbanization and its far-reaching effects--confirming the importance of continued research directed toward the identification of putative risk factors associated with psychiatric illness in urban settings. PMID:25936504

Thinking Frames.

ERIC Educational Resources Information Center

Perkins, D. N.

1986-01-01

Sifts through confusing intelligence theories, arguing that intelligence is a combination of influences involving power, tactics, and content. Good thinking is an unnatural act demanding evenhanded reasoning, problem finding (versus solving), and knowledge as invention. Discusses thinking frames guiding thought processes and the implications for…

Total Immersion Therapy for Autism.

ERIC Educational Resources Information Center

Bondy, Andrew

1999-01-01

This tongue-in-cheek humorous article reviews the therapeutic interventions available for children with autism by slightly changing the terminology used. Examples include "discrete trails,""indiscreet trails,""behavior oralysis,""incident training,""by-the-way training," the "unnatural language paradigm,""facilitated miscommunication," and…

Towards Direct Measurement of Ultrafast Vibrational Energy Flow in Proteins

NASA Astrophysics Data System (ADS)

Müller-Werkmeister, Henrike M.; Essig, Martin; Durkin, Patrick; Budisa, Nediljko; Bredenbeck, Jens

Vibrational energy transfer (VET) within a molecule can be investigated in great detail with ultrafast IR spectroscopy. We report on progress towards mapping of VET pathways in proteins using unnatural amino acids as site-specific probes.

Gamma-Nonanoic Lactone: Synthesis of a Fragrance and Flavor Enhancer in the Undergraduate Laboratory.

ERIC Educational Resources Information Center

Bunce, Richard A.; Reeves, Henry D.

1990-01-01

Described is an experiment in which students are able to synthesize an unnatural compound having the odor and flavor of coconuts. Laboratory equipment, procedures, and analysis of the product are discussed. (CW)

Ethical problems in an era where disasters have become a part of daily life: A qualitative study of healthcare workers in Turkey.

PubMed

Civaner, M Murat; Vatansever, Kevser; Pala, Kayihan

2017-01-01

Natural disasters, armed conflict, migration, and epidemics today occur more frequently, causing more death, displacement of people and economic loss. Their burden on health systems and healthcare workers (HCWs) is getting heavier accordingly. The ethical problems that arise in disaster settings may be different than the ones in daily practice, and can cause preventable harm or the violation of basic human rights. Understanding the types and the determinants of ethical challenges is crucial in order to find the most benevolent action while respecting the dignity of those affected people. Considering the limited scope of studies on ethical challenges within disaster settings, we set upon conducting a qualitative study among local HCWs. Our study was conducted in six cities of Turkey, a country where disasters are frequent, including armed conflict, terrorist attacks and a massive influx of refugees. In-depth interviews were carried out with a total of 31 HCWs working with various backgrounds and experience. Data analysis was done concurrently with ongoing interviews. Several fundamental elements currently hinder ethics in relief work. Attitudes of public authorities, politicians and relief organizations, the mismanagement of impromptu humanitarian action and relief and the media's mindset create ethical problems on the macro-level such as discrimination, unjust resource allocation and violation of personal rights, and can also directly cause or facilitate the emergence of problems on the micro-level. An important component which prevents humanitarian action towards victims is insufficient competence. The duty to care during epidemics and armed conflicts becomes controversial. Many participants defend a paternalistic approach related to autonomy. Confidentiality and privacy are either neglected or cannot be secured. Intervention in factors on the macro-level could have a significant effect in problem prevention. Improving guidelines and professional codes as well as educating HCWs are also areas for improvement. Also, ethical questions exposed within this study should be deliberated and actualized with universal consensus in order to guide HCWs and increase humane attitudes.

Health Effects of Climate Change

MedlinePlus

... in their leisure time. Deeply embedded in this fundamental relationship between climate and human life are the ... and emergency services to address disaster planning and management. Research to understand the benefits of alternative fuels, ...

A Sensitive and Versatile Fluorescent Activity Assay for ABHD6.

PubMed

Savinainen, Juha R; Navia-Paldanius, Dina; Laitinen, Jarmo T

2016-01-01

The α/β-hydrolase domain-containing 6 (ABHD6) enzyme is a newly found serine hydrolase whose substrate profile resembles that of monoacylglycerol lipase (MAGL), the major 2-arachidonoyl glycerol (2-AG) hydrolase in the brain. Here, we describe a sensitive fluorescent assay of ABHD6 activity in a 96-well-plate format that allows parallel testing of inhibitor activities of up to 40 compounds in a single assay. The method utilizes lysates of HEK293 cells transiently overexpressing human ABHD6 as the enzymatic source, and kinetically monitors glycerol liberated in the hydrolysis of 1(3)-AG, the preferred arachidonoyl glycerol isomer. Glycerol output is coupled to an enzymatic cascade generating the fluorescent end-product resorufin. The approach has major benefits compared to laborious traditional mass spectrometric methods and liquid scintillation-based assays, or approaches using unnatural substrates.

Epstein–Barr virus-associated lymphomas

PubMed Central

Shannon-Lowe, Claire; Rickinson, Alan B.

2017-01-01

Epstein–Barr virus (EBV), originally discovered through its association with Burkitt lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative lesions and malignant lymphomas of B-, T- and NK-cell origin. Some occur as rare accidents of virus persistence in the B lymphoid system, while others arise as a result of viral entry into unnatural target cells. The early finding that EBV is a potent B-cell growth transforming agent hinted at a simple oncogenic mechanism by which this virus could promote lymphomagenesis. In reality, the pathogenesis of EBV-associated lymphomas involves a complex interplay between different patterns of viral gene expression and cellular genetic changes. Here we review recent developments in our understanding of EBV-associated lymphomagenesis in both the immunocompetent and immunocompromised host. This article is part of the themed issue ‘Human oncogenic viruses’. PMID:28893938

Epstein-Barr virus-associated lymphomas.

PubMed

Shannon-Lowe, Claire; Rickinson, Alan B; Bell, Andrew I

2017-10-19

Epstein-Barr virus (EBV), originally discovered through its association with Burkitt lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative lesions and malignant lymphomas of B-, T- and NK-cell origin. Some occur as rare accidents of virus persistence in the B lymphoid system, while others arise as a result of viral entry into unnatural target cells. The early finding that EBV is a potent B-cell growth transforming agent hinted at a simple oncogenic mechanism by which this virus could promote lymphomagenesis. In reality, the pathogenesis of EBV-associated lymphomas involves a complex interplay between different patterns of viral gene expression and cellular genetic changes. Here we review recent developments in our understanding of EBV-associated lymphomagenesis in both the immunocompetent and immunocompromised host.This article is part of the themed issue 'Human oncogenic viruses'. © 2017 The Authors.

Why should we care about nonhuman animals during times of crisis?

PubMed

Appleby, Michael C; Stokes, Tonya

2008-01-01

Incentives to care for nonhuman animals derive in part from the extent to which people depend on animals for food, for livelihood, and for cultural and psychological reasons as well as from the duty to protect animals in their care. When attention is turned to solving and preventing animal welfare problems at times of crisis, it becomes clear that those problems are also associated with problems for human welfare and environmental impact. The incidence and spread of animal diseases is affected by how animals are treated, and this can have very important effects. Similarly, during disasters caused by either natural or human-made events, outcomes for animals are important both in themselves and for their effects on humans and the environment. The need to plan and prepare to care for animals in advance of disease pandemics and disasters - and then to provide coordinated, measured management in response when such crises occur - requires collaboration between all agencies involved as well as increasing attention and resources.

PREVENTION GUIDELINES SYSTEM/DATABASE

EPA Science Inventory

The Prevention Guidelines System gives public health practitioners quick access to the most current CDC recommendations and guidelines for the prevention, control, treatment and detection of infectious and chronic diseases, environmental hazards, natural or human-generated disast...

Occupational and public health considerations for work-hour limitations policy regarding public health workers during response to natural and human-caused disasters.

PubMed

Berkowitz, Murray R

2012-01-01

This article examines the occupational health considerations that might impact the health and wellbeing of public health workers during responses to natural (eg, floods and hurricanes) and human-caused (eg, terrorism, war, and shootings) disasters. There are a number of articles in the medical literature that argue the impact of how working long hours by house staff physicians, nurses, and first-responders may pose health and safety concerns regarding the patients being treated. The question examined here is how working long hours may pose health and/or safety concerns for the public health workers themselves, as well as to those in the communities they serve. The health problems related to sleep deprivation are reviewed. Current policies and legislations regarding work-hour limitations are examined. Policy implications are discussed.

Role of forensic odontologist in post mortem person identification

PubMed Central

Pramod, Jahagirdar B.; Marya, Anand; Sharma, Vidhii

2012-01-01

The natural teeth are the most durable organs in the bodies of vertebrates, and humankind's understanding of their own past and evolution relies heavily upon remnant dental evidence found as fossils. The use of features unique to the human dentition as an aid to personal identification is widely accepted within the forensic field. Comparative dental identifications play a major role in identifying the victims of violence, disaster or other mass tragedies. The comparison of ante-mortem and postmortem dental records to determine human identity has long been established. Indeed, it is still a major identification method in criminal investigations, mass disasters, grossly decomposed or traumatized bodies, and in other situations where visual identification is neither possible nor desirable. This article has comprehensively described some of the methods, and additional factors aiding in postmortem person identification. PMID:23559914

Disaster Victim Identification using Orthopedic Implants in the 2011 East-Japan Earthquake and Tsunami.

PubMed

Numata, Norio; Makinae, Haruka; Yoshida, Wataru; Daimon, Masao; Murakami, Hideki

2017-03-01

On March 11, 2011, an earthquake (magnitude 9.0) devastated Japan's east coast, and the associated tsunami resulted in social and mechanical destruction. Search for the missing people is still ongoing. Surgical implants are common in the general population. Medical implants usually have lot numbers, and their forensic use is common for victim identification. This investigation was conducted mainly in the cities of Kamaishi and Otsuchi, both of which were affected by the tsunami disaster in 2011. We visited 6 mortuaries with the police between March 20 (9 days after the tsunami) and April 20 (40 days after the tsunami) to examine the presence of surgical scars and related information. Unidentified human remains were investigated by visual and tactile examination. We also visited temples where the ashes were preserved. If implants were found, their lot numbers and estimated surgical procedures were recorded to determine positive identification. Ten of 233 sets of unidentified human remains before cremation displayed characteristics of a potential past surgical history. However, only 2 of these 233 sets had orthopedic implants. Instead, non-combustible orthopedic implants were found and recognized in 8 of the 331 sets of unidentified human ashes in the temples after cremation; the lot numbers were fully legible in 2 of the 8 sets. We estimated the surgical procedures, which led to positive identification. In conclusion, lot numbers and the surgical knowledge of orthopedic surgeons could assist with the positive identification of disaster victims. However, the relevant information can be erased after cremation.

A coupled human and landscape conceptual model of risk and resilience in mountain communities

NASA Astrophysics Data System (ADS)

Ramirez, Jorge; Haisch, Tina; Martius, Olivia; Mayer, Heike; Ifejika Speranza, Chinwe; Keiler, Margreth

2017-04-01

Recent extreme natural disasters have focused the attention of the global community to society's vulnerability to these events. Simultaneously these natural disasters occur within a broader social and physical context that is interconnected and may include social upheavals, economic crises, and climate change. While progress has been made to mitigate and adapt to natural hazards, much of the existing research lacks interdisciplinary approaches that equally consider both natural and social processes. More importantly, this lack of integration between approaches remains a major challenge in developing disaster risk management plans for communities. In this study we focus on European Alpine communities that face numerous human and environmental risks and differ regarding their ability to cope with these risks and develop resilience. Herein we present a conceptual model of mountain communities exposed to socio-economic (e.g. economic downturn) and biophysical (e.g. floods) "shocks". We identify system boundaries, structure, components, and processes required to describe both human and landscape systems for mountain communities. More importantly we determine feedbacks within and between both systems. The purpose of the model is to investigate which shocks overcome the buffering capacity of mountain communities, and determine which shocks have a greater effect on mountain communities. Socioeconomic, climate, and hazard 'shock' scenarios have been developed for communities with different geographic sizes. Examples of inputs for the model and methods required to test the model are provided. Guided by the model and scenarios we discuss potential outcomes regarding community resilience.

Managed traffic evacuation using distributed sensor processing

NASA Astrophysics Data System (ADS)

Ramuhalli, Pradeep; Biswas, Subir

2005-05-01

This paper presents an integrated sensor network and distributed event processing architecture for managed in-building traffic evacuation during natural and human-caused disasters, including earthquakes, fire and biological/chemical terrorist attacks. The proposed wireless sensor network protocols and distributed event processing mechanisms offer a new distributed paradigm for improving reliability in building evacuation and disaster management. The networking component of the system is constructed using distributed wireless sensors for measuring environmental parameters such as temperature, humidity, and detecting unusual events such as smoke, structural failures, vibration, biological/chemical or nuclear agents. Distributed event processing algorithms will be executed by these sensor nodes to detect the propagation pattern of the disaster and to measure the concentration and activity of human traffic in different parts of the building. Based on this information, dynamic evacuation decisions are taken for maximizing the evacuation speed and minimizing unwanted incidents such as human exposure to harmful agents and stampedes near exits. A set of audio-visual indicators and actuators are used for aiding the automated evacuation process. In this paper we develop integrated protocols, algorithms and their simulation models for the proposed sensor networking and the distributed event processing framework. Also, efficient harnessing of the individually low, but collectively massive, processing abilities of the sensor nodes is a powerful concept behind our proposed distributed event processing algorithms. Results obtained through simulation in this paper are used for a detailed characterization of the proposed evacuation management system and its associated algorithmic components.

Waiting for Disasters: A Risk Reduction Assessment of Technological Disasters

NASA Astrophysics Data System (ADS)

Rovins, Jane; Winningham, Sam

2010-05-01

This session provides a risk reduction/mitigation assessment of natural hazards causation of technological disasters and possible solution. People use technology in an attempt to not only control their environment but nature itself in order to make them feel safe and productive. Most strategies for managing hazards followed a traditional planning model i.e. study the problem, identify and implement a solution, and move on to the next problem. This approach is often viewed as static model and risk reduction is more of an upward, positive, linear trend. However, technological disasters do not allow risk reduction action to neatly fit this upward, positive, linear trend with actual or potential threats to the environment and society. There are different types of technological disasters, including industrial accidents; pipeline ruptures; accidents at power, water and heat supply systems and other lines of communication; sudden collapse of buildings and mines; air crashes; shipwrecks; automobile and railway accidents to name a few. Natural factors can play an essential role in triggering or magnifying technological disasters. They can result from the direct destruction of given technical objects by a hazardous natural process such as the destruction of an atomic power plant or chemical plant due to an earthquake. Other examples would include the destruction of communications or infrastructure systems by heavy snowfalls, strong winds, avalanches. Events in the past ten years clearly demonstrate that natural disasters and the technological disasters that accompany them are not problems that can be solved in isolation and risk reduction can play an important part. Risk reduction was designed to head off the continuing rising financial and structural tolls from disasters. All Hazard Risk Reduction planning was supposed to include not only natural, but technological, and human-made disasters as well. The subsequent disaster risk reduction (DRR) indicators were to provide the corner stone to sustained risk reduction. We are able to look at the ongoing work by UNISDR and other partners to develop DRR indicators to track progress toward the goals outlined in the Hyogo Framework for Action adopted by 168 countries in Kobe, Japan in January 2005. In addition, we can look at various global examples. Therefore the true question we shall address is whether or not the DRR indicators form a virtuous circle was created with risk reduction with a series of positive events triggering a self-perpetuating pattern of other positive occurrences or a vicious circle.

USGS Emergency Response and the International Charter Space and Major Disasters

NASA Astrophysics Data System (ADS)

Jones, B. K.

2009-12-01

Responding to catastrophic natural disasters requires information. When the flow of information on the ground is interrupted by crises such as earthquakes, landslides, volcanoes, hurricanes, and floods, satellite imagery and aerial photographs become invaluable tools in revealing post-disaster conditions and in aiding disaster response and recovery efforts. USGS is a global clearinghouse for remotely sensed disaster imagery. It is also a source of innovative products derived from satellite imagery that can provide unique overviews as well as important details about the impacts of disasters. Repeatedly, USGS and its resources have proven their worth in assisting with disaster recovery activities in the United States and abroad. USGS has a well-established role in emergency response in the United States. It works closely with the Federal Emergency Management Agency (FEMA) by providing first responders with satellite and aerial images of disaster-impacted sites and products developed from those images. FEMA’s partnership with the USGS began in 1999 when the agency established USGS as its executive agent for the acquisition and coordination of aerial and satellite remote sensing data. Understanding the terrain affords FEMA the vital perspective needed to effectively respond to the devastation many disasters leave behind. The combination of the USGS image archive, coupled with its global data transfer capability and on-site science staff, was instrumental in the USGS becoming a participating agency in the International Charter Space and Major Disasters. This participation provides the USGS with access to international members space agencies, to information on their methodology in disaster response, and to data from the satellites they operate. Such access enhances the USGS’ ability to respond to global emergencies and to disasters that occur in the United States (US). As one example, the Charter agencies provided over 75 images to the US in support of Hurricane Katrina. The International Charter mission is to provide a unified system of space data acquisition and delivery to those affected by natural or man-made disasters. Each member space agency has committed resources to support the provisions of the Charter and thus is helping to mitigate the effects of disasters on human life and property. The International Charter has been in formal operation since November 1, 2000. An Authorized User calls a single number to request the mobilization of satellite imagery and associated ground station support of the Charter’s member agencies to obtain data and information on a disaster occurrence. The International Charter is supported by Argentinean, Canadian, European, Indian, Japanese, Chinese, and U.S. satellite operators, as well as through U.S. and foreign commercial satellite firms. These operators can provide a wide variety of imagery and information under various environmental conditions. The Charter works in close cooperation with the intergovernmental Group on Earth Observations (GEO), and with United Nations bodies such as the UN Office of Outer Space Affairs (UN OOSA) and the UN Institute for Training and Research (UNITAR) Operational Satellite Applications Programe (UNOSAT). These organizations play an important role in maximizing the Charter’s use with U.N. member states.

Extreme weather events and infectious disease outbreaks.

PubMed

McMichael, Anthony J

2015-01-01

Human-driven climatic changes will fundamentally influence patterns of human health, including infectious disease clusters and epidemics following extreme weather events. Extreme weather events are projected to increase further with the advance of human-driven climate change. Both recent and historical experiences indicate that infectious disease outbreaks very often follow extreme weather events, as microbes, vectors and reservoir animal hosts exploit the disrupted social and environmental conditions of extreme weather events. This review article examines infectious disease risks associated with extreme weather events; it draws on recent experiences including Hurricane Katrina in 2005 and the 2010 Pakistan mega-floods, and historical examples from previous centuries of epidemics and 'pestilence' associated with extreme weather disasters and climatic changes. A fuller understanding of climatic change, the precursors and triggers of extreme weather events and health consequences is needed in order to anticipate and respond to the infectious disease risks associated with human-driven climate change. Post-event risks to human health can be constrained, nonetheless, by reducing background rates of persistent infection, preparatory action such as coordinated disease surveillance and vaccination coverage, and strengthened disaster response. In the face of changing climate and weather conditions, it is critically important to think in ecological terms about the determinants of health, disease and death in human populations.

Emergency Response of Iranian Hospitals Against Disasters: A Practical Framework for Improvement.

PubMed

Janati, Ali; Sadeghi-Bazargani, Homayoun; Hasanpoor, Edris; Sokhanvar, Mobin; HaghGoshyie, Elaheh; Salehi, Abdollah

2018-04-01

Hospital emergency management is a continuous process that requires monolithic integration of planning and response attempts with local and national schemes. The aim of the current study is to evaluate emergency response by hospitals against potential disasters in Tabriz, north-west Iran. A cross-sectional study was conducted in the city of Tabriz, in Iran, in 2016. The study population included all hospitals in Tabriz. A total of 18 hospitals were assessed. The hospital emergency response checklist was used to collect data. Tool components included command and control, communication, safety and security, triage, surge capacity, continuity of essential services, human resources, logistics and supply management, and post-disaster recovery. Data entry and analysis were carried out using SPSS software (version 20). The results showed that the emergency response rate of hospitals was 54.26% in Tabriz. The lowest response rates were for Shafaa hospital (18.89%) and the highest response rates were for Razi Hospital (91.67%). The components of hospital emergency response were assessed to be between 48.07% (surge capacity) and 58.95% (communication). On the basis of the World Health Organization checklist, the emergency response rate for hospitals in Tabriz was only 54.26%. Therefore, hospital emergency responses against disasters have to be improved and must be made to reach 100%. It is essential to design a comprehensive framework for hospital emergency response. (Disaster Med Public Health Preparedness. 2018;12:166-171).

Recovery Migration after Hurricanes Katrina and Rita: Spatial Concentration and Intensification in the Migration System

PubMed Central

Fussell, Elizabeth; DeWaard, Jack

2015-01-01

Changes in the human migration systems of Hurricane Katrina- and Rita-affected Gulf of Mexico coastline counties provide an example of how climate change may affect coastal populations. Crude climate change models predict a mass migration of “climate refugees,” but an emerging literature on environmental migration suggests most migration will be short-distance and short-duration within existing migration systems, with implications for the population recovery of disaster-struck places. In this research, we derive a series of hypotheses on recovery migration predicting how the migration system of hurricane-affected coastline counties in the Gulf of Mexico was likely to have changed between the pre-disaster and the recovery periods. We test these hypotheses using data from the Internal Revenue Service on annual county-level migration flows, comparing the recovery period migration system (2007–2009) to the pre-disaster period (1999–2004). By observing county-to-county ties and flows we find that recovery migration was strong, as the migration system of the disaster-affected coastline counties became more spatially concentrated while flows within it intensified and became more urbanized. Our analysis demonstrates how migration systems are likely to be affected by the more intense and frequent storms anticipated by climate change scenarios with implications for the population recovery of disaster-affected places. PMID:26084982

Extreme seismicity and disaster risks: Hazard versus vulnerability (Invited)

NASA Astrophysics Data System (ADS)

Ismail-Zadeh, A.

2013-12-01

Although the extreme nature of earthquakes has been known for millennia due to the resultant devastation from many of them, the vulnerability of our civilization to extreme seismic events is still growing. It is partly because of the increase in the number of high-risk objects and clustering of populations and infrastructure in the areas prone to seismic hazards. Today an earthquake may affect several hundreds thousand lives and cause significant damage up to hundred billion dollars; it can trigger an ecological catastrophe if occurs in close vicinity to a nuclear power plant. Two types of extreme natural events can be distinguished: (i) large magnitude low probability events, and (ii) the events leading to disasters. Although the first-type events may affect earthquake-prone countries directly or indirectly (as tsunamis, landslides etc.), the second-type events occur mainly in economically less-developed countries where the vulnerability is high and the resilience is low. Although earthquake hazards cannot be reduced, vulnerability to extreme events can be diminished by monitoring human systems and by relevant laws preventing an increase in vulnerability. Significant new knowledge should be gained on extreme seismicity through observations, monitoring, analysis, modeling, comprehensive hazard assessment, prediction, and interpretations to assist in disaster risk analysis. The advanced disaster risk communication skill should be developed to link scientists, emergency management authorities, and the public. Natural, social, economic, and political reasons leading to disasters due to earthquakes will be discussed.

Did we really #prayfornepal? Instagram posts as a massive digital funeral in Nepal earthquake aftermath

NASA Astrophysics Data System (ADS)

Kamil, P. I.; Pratama, A. J.; Hidayatulloh, A.

2016-05-01

Social media has been part of our daily life for years, and now it has become a treasure trove of data for social scientists to mine. Using our own data mining engine we downloaded 1500 Instagram posts related to the Nepal earthquake in April 2015, a disaster which caused tremendous losses counted in human lives and infrastructures. We predicted that the social media will be a place where people respond and express themselves emotionally in light of a disaster of such massive scale, a "megadeath" event. We ended up with data on 1017 posts tracked with the hashtag #prayfornepal, consisting of the post's date, time, geolocation, image, post ID, username and ID, caption, and hashtag. We categorized the posts into 7 categories and found that most of the photos (30,29%) are related to Nepal but not directly related to the disasters, which reflects death imprint, one of psychosocial responses after a megadeath event. Other analyses were done to compare each photo category, including geo-location, hashtag network and caption network which will be visualized with ArcGIS, NodeXL, Gephi, and our own word cloud engine to examine other digital reactions to Nepal Earthquake in Instagram. This study can give an overview of how community reacts to a disaster in digital world and utilize it for disaster response and awareness.

Post-disaster medical rescue strategy in tropical regions.

PubMed

Li, Xiang-Hui; Hou, Shi-Ke; Zheng, Jing-Chen; Fan, Hao-Jun; Song, Jian-Qi

2012-01-01

Earthquakes, floods, droughts, storms, mudslides, landslides, and forest wild fires are serious threats to human lives and properties. The present study aimed to study the environmental characteristics and pathogenic traits, recapitulate experiences, and augment applications of medical reliefs in tropical regions. Analysis was made on work and projects of emergency medical rescue, based on information and data collected from 3 emergency medical rescue missions of China International Search and Rescue Team to overseas earthquakes and tsunamis aftermaths in tropical disaster regions - Indonesia-Aceh, Indonesia-Yogyakarta, and Haiti-Port au Prince. Shock, infection and heat stroke were frequently encountered in addition to outbreaks of infectious diseases, skin diseases, and diarrhea during post-disaster emergency medical rescue in tropical regions. High temperature, high humidity, and proliferation of microorganisms and parasites are the characteristics of tropical climate that impose strict requirements on the preparation of rescue work including selective team members suitable for a particular rescue mission and the provisioning of medical equipment and life support materials. The overseas rescue mission itself needs a scientific, efficient, simple workflow for providing efficient emergency medical assistance. Since shock and infection are major tasks in post-disaster treatment of severely injured victims in tropical regions, the prevention and diagnosis of hyperthermia, insect-borne infectious diseases, tropic skin diseases, infectious diarrhea, and pest harms of disaster victims and rescue team staff should be emphasized during the rescue operations.

Chilean geo client application for disasters

NASA Astrophysics Data System (ADS)

Suárez, Rodrigo F.; Lovison, Lucia; Potters, Martinus

2018-05-01

The global network of the Group on Earth Observation, GEO, connects all kinds of professionals from public and private institutions with data providers, sharing information to face the challenges of global changes and human development and they are creating a Global Earth Observation System of Systems (GEOSS) to connect existing data infrastructures. A GEOSS Architecture Implementation Pilot Project for Disasters in Chile (AIP-8) was created as part of a capacity building initiative and representatives of different national agencies in Chile, along with international experts, formed a GEOSS Capacity Building Working Group (Lovison et al, 2016). Consistent with the objectives of GEOSS AIP-8 Chile, we developed and implemented a prototype service based on web services, mobile applications and other communication channels, which allows connecting different sources of information, aiming to reduce population vulnerability to natural disasters such as: earthquakes, flooding, wild fires and tsunamis, which is presented here. The GEO Chile client application is a JavaScript application using GEODAB brokering services, GIS technology and disaster information provided by national and international disaster services, including public and private organizations, where cartography becomes fundamental as a tool to provide realism and ubiquity to the information. Seven hotpots are targeted: Calbuco, Copahue and Villarrica volcanoes areas, Valparaíso city, which is frequently a victim of wildfires in the zone where population meets forest and Iquique, Illapel and Talcahuano, areas frequently struck by earthquakes and tsunamis.

Sensuality test result for application to space foods of the disaster food

NASA Astrophysics Data System (ADS)

Katayama, Naomi; Okano, Yukimi; Kondou, Syouko

2016-07-01

The human became able to stay in the space for a long term. This is very important to step forward to the first step for Mars emigration. The long-term stay in the space has a big great stress. The space foods are important to keep a body and mind from those stress. The maintenance of the function of the astronaut of immunity and a meal for the hormone to keep the balance are necessary. As for both the space foods and the disaster meal, room-temperature preservation is possible for a long term. However, the taste is important to even disaster food. The person is repeated if not delicious and cannot eat disaster foods. The sensuality test result about the taste of the disaster food is important. Melon bun, Strawberry jam bun, Cream bun, Maple caramel, Bean-jam bun, Croissant, Croissant Rich, Ogura croissant, Buran croissant, Waffle, Maple waffle, Buran waffle, Strawberry milk waffle, Chocolate bun A cream bun is special. The bean-jam bun is very familiar bread for a Japanese. Because a lot of dietary fibers were good for health as for the buran croissant, an evaluation was high. We think that it is similar in the space foods. It is necessary to think about a universal meal in the space foods. We think that it is necessary to prepare the food which a person of the whole world likes.

GIS and local knowledge in disaster management: a case study of flood risk mapping in Viet Nam.

PubMed

Tran, Phong; Shaw, Rajib; Chantry, Guillaume; Norton, John

2009-03-01

Linking community knowledge with modern techniques to record and analyse risk related data is one way of engaging and mobilising community capacity. This paper discusses the use of the Geographic Information System (GIS) at the local level and the need for integrating modern technology and indigenous knowledge into disaster management. It suggests a way to mobilise available human and technical resources in order to strengthen a good partnership between local communities and local and national institutions. The paper also analyses the current vulnerability of two communes by correlating hazard risk and loss/damage caused by disasters and the contribution that domestic risk maps in the community can make to reduce this risk. The disadvantages, advantages and lessons learned from the GIS flood risk mapping project are presented through the case study of the Quang Tho Commune in Thua Thien Hue province, central Viet Nam.

Physics of Earthquake Disaster: From Crustal Rupture to Building Collapse

NASA Astrophysics Data System (ADS)

Uenishi, Koji

2018-05-01

Earthquakes of relatively greater magnitude may cause serious, sometimes unexpected failures of natural and human-made structures, either on the surface, underground, or even at sea. In this review, by treating several examples of extraordinary earthquake-related failures that range from the collapse of every second building in a commune to the initiation of spontaneous crustal rupture at depth, we consider the physical background behind the apparently abnormal earthquake disaster. Simple but rigorous dynamic analyses reveal that such seemingly unusual failures actually occurred for obvious reasons, which may remain unrecognized in part because in conventional seismic analyses only kinematic aspects of the effects of lower-frequency seismic waves below 1 Hz are normally considered. Instead of kinematics, some dynamic approach that takes into account the influence of higher-frequency components of waves over 1 Hz will be needed to anticipate and explain such extraordinary phenomena and mitigate the impact of earthquake disaster in the future.

Flowering Phenology: An Activity to Introduce Human & Environmental Effects on Plant Reproduction

ERIC Educational Resources Information Center

Neil, Kaesha

2009-01-01

Global and local climate change has become an important topic in the last few years. Concerns regarding the impact of climate changes on ecosystems in general, resources used by humans (e.g., water, energy, crops), and the intensity and frequency of natural disasters are driving the interest. Phenology is one way researchers are studying historic…

[Cloning: applications in humans 2. Ethical considerations].

PubMed

de Wert, G M; Geraedts, J P

2001-05-01

Reproductive cloning in adults/children evokes unfavourable reactions. Direct objections are that cloning is unnatural, that it affects human dignity and violates the individual's right to genetic uniqueness. Consequential objections concern unjustified health risks for the progeny, unjustified psychosocial risks for the clone child and the risk of cloning for eugenetic purposes. There is consensus that reproductive cloning of existing persons is unjustify as yet because of the health risks for the offspring. Reproductive cloning of embryos is possible by means of nucleus transplantation and of embryo splitting. The ethical analysis of reproductive cloning of embryos depends on the purposes and applications. At least some of the moral objections against cloning of adults/children are not or not completely applicable to reproductive cloning of embryos. Conditions to be put to reproductive cloning of embryos are efficacy, safety and, at least for the time being, avoidance of asynchrony in transferring identical embryos. The ethical aspects of its application in the context of genetical reproductive techniques must be evaluated separately. Therapeutic cloning may be acceptable if alternatives are lacking.

[Cloning: applications in humans. II. Ethical considerations].

PubMed

de Wert, G M; Geraedts, J P

2000-05-13

Reproductive cloning in adults/children evokes unfavourable reactions. Direct objections are that cloning is unnatural, that it affects human dignity and violates the individual's right to genetic uniqueness. Consequential objections concern unjustified health risks for the progeny, unjustified psychosocial risks for the clone child and the risk of cloning for eugenetic purposes. There is consensus that reproductive cloning of existing persons is unjustifiable as yet because of the health risks for the offspring. Reproductive cloning of embryos is possible by means of nucleus transplantation and of embryo splitting. The ethical analysis of reproductive cloning of embryos depends on the purposes and applications. At least some of the moral objections against cloning of adults/children are not or not completely applicable to reproductive cloning of embryos. Conditions to be put to reproductive cloning of embryos are efficacy, safety and, at least for the time being, avoidance of asynchrony in transferring identical embryos. The ethical aspects of its application in the context of genetical reproductive techniques must be evaluated separately. Therapeutic cloning may be acceptable if alternatives are lacking.

Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses.

PubMed

Geslain, Renaud; Cubells, Laia; Bori-Sanz, Teresa; Alvarez-Medina, Roberto; Rossell, David; Martí, Elisa; Ribas de Pouplana, Lluís

2010-03-01

Misfolded proteins are caused by genomic mutations, aberrant splicing events, translation errors or environmental factors. The accumulation of misfolded proteins is a phenomenon connected to several human disorders, and is managed by stress responses specific to the cellular compartments being affected. In wild-type cells these mechanisms of stress response can be experimentally induced by expressing recombinant misfolded proteins or by incubating cells with large concentrations of amino acid analogues. Here, we report a novel approach for the induction of stress responses to protein aggregation. Our method is based on engineered transfer RNAs that can be expressed in cells or tissues, where they actively integrate in the translation machinery causing general proteome substitutions. This strategy allows for the introduction of mutations of increasing severity randomly in the proteome, without exposing cells to unnatural compounds. Here, we show that this approach can be used for the differential activation of the stress response in the Endoplasmic Reticulum (ER). As an example of the applications of this method, we have applied it to the identification of human microRNAs activated or repressed during unfolded protein stress.

Visual Contrast Enhancement Algorithm Based on Histogram Equalization

PubMed Central

Ting, Chih-Chung; Wu, Bing-Fei; Chung, Meng-Liang; Chiu, Chung-Cheng; Wu, Ya-Ching

2015-01-01

Image enhancement techniques primarily improve the contrast of an image to lend it a better appearance. One of the popular enhancement methods is histogram equalization (HE) because of its simplicity and effectiveness. However, it is rarely applied to consumer electronics products because it can cause excessive contrast enhancement and feature loss problems. These problems make the images processed by HE look unnatural and introduce unwanted artifacts in them. In this study, a visual contrast enhancement algorithm (VCEA) based on HE is proposed. VCEA considers the requirements of the human visual perception in order to address the drawbacks of HE. It effectively solves the excessive contrast enhancement problem by adjusting the spaces between two adjacent gray values of the HE histogram. In addition, VCEA reduces the effects of the feature loss problem by using the obtained spaces. Furthermore, VCEA enhances the detailed textures of an image to generate an enhanced image with better visual quality. Experimental results show that images obtained by applying VCEA have higher contrast and are more suited to human visual perception than those processed by HE and other HE-based methods. PMID:26184219