Debris mitigation methods for bridge piers.

DOT National Transportation Integrated Search

2012-06-01

Debris accumulation on bridge piers is an on-going national problem that can obstruct the waterway openings at bridges and result in significant erosion of stream banks and scour at abutments and piers. In some cases, the accumulation of debris can a...

Debris mitigation methods for bridge piers : tech transfer summary.

DOT National Transportation Integrated Search

2012-06-01

Problem statement: Debris accumulation on bridge piers is an on-going national problem that can obstruct waterway openings at bridges and also result in significant erosion of stream banks and scour at abutments and piers. : In some cases, debris acc...

Self-expanding metallic stent as a bridge to surgery in the treatment of left colon cancer obstruction: Cost-benefit analysis and oncologic results.

PubMed

Flor-Lorente, Blas; Báguena, Gloria; Frasson, Matteo; García-Granero, Alvaro; Cervantes, Andrés; Sanchiz, Vicente; Peña, Andres; Espí, Alejandro; Esclapez, Pedro; García-Granero, Eduardo

2017-03-01

The use of a self-expanding metallic stent as a bridge to surgery in acute malignant left colonic obstruction has been suggested as an alternative treatment to emergency surgery. The aim of the present study was to compare the morbi-mortality, cost-benefit and long-term oncological outcomes of both therapeutic options. This is a prospective, comparative, controlled, non-randomized study (2005-2010) performed in a specialized unit. The study included 82 patients with left colon cancer obstruction treated by stent as a bridge to surgery (n=27) or emergency surgery (n=55) operated with local curative intention. The main outcome measures (postoperative morbi-mortaliy, cost-benefit, stoma rate and long-term oncological outcomes) were compared based on an "intention-to-treat" analysis. There were no significant statistical differences between the two groups in terms of preoperative data and tumor characteristics. The technically successful stenting rate was 88.9% (11.1% perforation during stent placement) and clinical success was 81.4%. No difference was observed in postoperative morbi-mortality rates. The primary anastomosis rate was higher in the bridge to surgery group compared to the emergency surgery group (77.8% vs. 56.4%; P=.05). The mean costs in the emergency surgery group resulted to be €1,391.9 more expensive per patient than in the bridge to surgery group. There was no significant statistical difference in oncological long-term outcomes. The use of self-expanding metalllic stents as a bridge to surgery is a safe option in the urgent treatment of obstructive left colon cancer, with similar short and long-term results compared to direct surgery, inferior mean costs and a higher rate of primary anastomosis. Copyright © 2017 AEC. Publicado por Elsevier España, S.L.U. All rights reserved.

14 CFR 399.36 - Unreasonable discrimination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Unreasonable discrimination. 399.36 Section... Unreasonable discrimination. (a) As used in this section: (1) Unreasonable discrimination means unjust discrimination or unreasonable preference or prejudice; and (2) Rate means rate, fare, or charge. (b) Except in...

14 CFR 399.36 - Unreasonable discrimination.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Unreasonable discrimination. 399.36 Section... Unreasonable discrimination. (a) As used in this section: (1) Unreasonable discrimination means unjust discrimination or unreasonable preference or prejudice; and (2) Rate means rate, fare, or charge. (b) Except in...

14 CFR 399.36 - Unreasonable discrimination.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Unreasonable discrimination. 399.36 Section... Unreasonable discrimination. (a) As used in this section: (1) Unreasonable discrimination means unjust discrimination or unreasonable preference or prejudice; and (2) Rate means rate, fare, or charge. (b) Except in...

Endoscopic Stenting as Bridge to Surgery versus Emergency Resection for Left-Sided Malignant Colorectal Obstruction: An Updated Meta-Analysis

PubMed Central

Ceresoli, Marco; Fugazzola, Paola; Ansaloni, Luca

2017-01-01

Introduction Emergency resection represents the traditional treatment for left-sided malignant obstruction. However, the placement of self-expanding metallic stents and delayed surgery has been proposed as an alternative approach. The aim of the current meta-analysis was to review the available evidence, with particular interest for the short-term outcomes, including a recent multicentre RCT. Methods We considered randomized controlled trials comparing stenting as a bridge to surgery and emergency surgery for the management of left-sided malignant large bowel obstruction, performing a systematic review in MEDLINE, PubMed database, and the Cochrane libraries. Results We initially identified a total of 2543 studies. After the elimination of duplicates and the screening of titles and abstracts, seven studies, for a total of 448 patients, were considered. The current meta-analysis revealed no difference in the mortality rate between the stent group and the emergency surgery group; the postoperative complication rate (37.84% versus 54.87%, P = 0.02), the stoma rate (28.8% versus 46.02%, P < 0.0001), and the incidence of wound infection (8.11% versus 15.49%, P = 0.01) were reduced after stent as a bridge to surgery. Conclusion Colonic stenting as a bridge to surgery appears to be a safe approach to malignant large bowel obstruction. Possible advantages of this treatment can be identified in a reduced incidence of postoperative complications and a lower stoma rate. Further RCTs considering long-term outcomes and cost-effectiveness analysis are needed. PMID:28761765

[Findings from Total Colonoscopy in Obstructive Colorectal Cancer Patients Who Underwent Stent Placement as a Bridge to Surgery(BTS)].

PubMed

Maruo, Hirotoshi; Tsuyuki, Hajime; Kojima, Tadahiro; Koreyasu, Ryohei; Nakamura, Koichi; Higashi, Yukihiro; Shoji, Tsuyoshi; Yamazaki, Masanori; Nishiyama, Raisuke; Ito, Tatsuhiro; Koike, Kota; Ikeda, Takashi; Takayanagi, Yasuhiro; Kubota, Hiroyuki

2017-11-01

We clinically investigated 34 patients with obstructive colorectal cancer who underwent placement of a colonic stent as a bridge to surgery(BTS), focusing on endoscopic findings after stent placement.Twenty -nine patients(85.3%)underwent colonoscopy after stent placement, and the entire large intestine could be observed in 28(96.6%).Coexisting lesions were observed in 22(78.6%)of these 28 patients.The lesions comprised adenomatous polyps in 17 patients(60.7%), synchronous colon cancers in 5 patients(17.9%), and obstructive colitis in 3 patients(10.7%), with some overlapping cases.All patients with multiple cancers underwent one-stage surgery, and all lesions were excised at the same time.Colonoscopy after colonic stent placement is important for preoperative diagnosis of coexisting lesions and planning the extent of resection. These considerations support the utility of colonic stenting for BTS.

46 CFR 92.03-1 - Navigation bridge visibility.

Code of Federal Regulations, 2010 CFR

2010-10-01

... after September 7, 1990, must meet the following requirements: (a) The field of vision from the... obstruction must not exceed 5 degrees. (2) From the conning position, the horizontal field of vision extends... paragraph (a)(1) of this section. (3) From each bridge wing, the field of vision extends over an arc from at...

Self-expandable metal stents for malignant colonic obstruction: data from a retrospective regional SIED-AIGO study.

PubMed

Di Mitri, Roberto; Mocciaro, Filippo; Traina, Mario; Montalbano, Luigi Maria; Familiari, Luigi; D'Amore, Fabio; Raimondo, Dario; Virgilio, Clara; Tarantino, Ilaria; Barresi, Luca; Giunta, Marco; Borina, Eleonora; Borruto, Antonino; Marino, Antonino

2014-03-01

Self-expandable metal stents are a non-surgical option for the treatment of symptomatic malignant colorectal obstruction as palliative treatment or as a bridge to surgery. To report data from a regional study on self-expandable metal stent (SEMS) placement for malignant colorectal obstruction. Two hundred and four patients (male 54.9%, mean age of 69.5 ± 14.2) were retrospectively evaluated and data on technical and clinical success, and complications, were analyzed. Technical and clinical success rates were 99% and 94.6% respectively, with 36.7% treated on an emergency basis and 63.3% electively. Palliative treatment was administered to 70.1%, and as a bridge to surgery for 29.9%. Complications were 17 neoplastic ingrowths, 10 stent migrations, and 4 perforations. Palliative treatment was associated with a higher risk of stent ingrowth (p=0.003), and chemotherapy with a lower risk of stent ingrowth (p=0.009). This regional study, although it has certain limitations, confirms the positive role of self-expandable metal stents in the treatment of symptomatic malignant colorectal obstruction, and that chemotherapy decreases the risk of ingrowth. Copyright © 2013 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

[Sixteen Cases of Colon Stenting as a Bridge to Surgery(BTS)for Obstructive Colorectal Cancer].

PubMed

Otsuka, Ryo; Saito, Shuji; Hirayama, Ryouichi; Miura, Yasuaki; Sasaki, Kazunori; Miyajima, Ayako; Kuwamoto, Nobutsuna; Kataoka, Ryoko; Shindo, Yukito; Fujita, Rikiya

2017-11-01

Colonic stent insertion is widely used as a bridge to surgery(BTS)for obstructive colorectal cancer. Stenting can shorten hospitalization and decrease complication and colostomy rates in comparison with emergency surgery. We investigated patients who underwent colonic stent insertion for BTS in our hospital. Sixteen patients(8 men, 8 women) with a colorectal obstruction score of 0 or 1 who underwent colonic stent insertion as a BTS between April 2015 and April 2017 period were investigated. Mean patient age was 68.2(45-94)years. Technical success was obtained in all patients, and clinical success in 14(87%). Total colonoscopy was possible via stent in 10 patients. Nine patients were temporarily discharged from the hospital, and median time to operation was 18(2-43)days. Laparoscopic resection was performed in 14 patients, and anastomotic leakage was a postoperative complication in 1 patient. Colostomy was performed in only 1 patient with anastomotic leakage. Good results were obtained with careful patient selection and safe colonic stent insertion.

47 CFR 8.7 - No unreasonable discrimination.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 1 2013-10-01 2013-10-01 false No unreasonable discrimination. 8.7 Section 8.7... discrimination. A person engaged in the provision of fixed broadband Internet access service, insofar as such... unreasonable discrimination. ...

[An Analysis of Placement of a Self-Expanding Metallic Stent as Bridge to Surgery for Surgical Resection of StageⅣ Obstructive Colorectal Cancers].

PubMed

Kawahara, Yohei; Terada, Itsuro; Terai, Shiro; Watanabe, Toshifumi; Amaya, Koji; Yamamoto, Seiichi; Kaji, Masahide; Maeda, Kiichi; Shimizu, Koichi

2015-11-01

In our institution, placement of a self-expanding metallic stent (SEMS) for obstructive colorectal cancer to avoid emergency operations, namely as a bridge to surgery (BTS), was introduced in April 2012. Here, we assess the efficacy and safety of pre-operative SEMS placement for treatment of Stage Ⅳ obstructive colorectal cancer. We analyzed a total of 44 cases of Stage Ⅳ colorectal cancer, which consisted of 13 obstructive cases that were surgically resected following SEMS placement as BTS (BTS group), and 31 cases that were resected in elective operations without pre-operative SEMS placement (Ope group), from April 2012 to August 2014. None of the patients had any adverse events during the SEMS procedure or after SEMS placement, and all patients of BTS group could undergo the planned operations after sufficient decompression. In the postoperative period, 1 patient of BTS group (7.7%) had anastomosis bleeding, but no other complications, including anastomosis leakage, were observed in BTS group. However more progressive primary tumors were resected in BTS group (p=0.0115), there were no significant differences for post-operative course between the 2 groups; this indicated avoiding high-risk emergency operations contributed to adequate short-term outcomes in BTS group comparable to those in Ope group. SEMS placement as BTS could be performed safely for Stage Ⅳ obstructive colorectal cancer cases, and was 1 of the effective strategies for local treatment.

Detailed scour measurements around a debris accumulation

USGS Publications Warehouse

Mueller, David S.; Parola, Arthur C.

1998-01-01

Detailed scour measurements were made at Farm-Market 2004 over the Brazos River near Lake Jackson, Tex. during flooding in October 1994. Woody debris accumulations on bents 6, 7, and 8 obstructed flow through the bridge, causing scour of the streambed. Measurements at the site included three-dimensional velocities, channel bathymetry, water-surface elevations, water-surface slope, and discharge. Channel geometry upstream from the bridge caused approach conditions to be nonuniform.

23 CFR 650.403 - Definition of terms.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., STRUCTURES, AND HYDRAULICS Highway Bridge Replacement and Rehabilitation Program § 650.403 Definition of... depression or an obstruction, such as water, a highway, or a railway, having a track or passageway for...

23 CFR 650.403 - Definition of terms.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., STRUCTURES, AND HYDRAULICS Highway Bridge Replacement and Rehabilitation Program § 650.403 Definition of... depression or an obstruction, such as water, a highway, or a railway, having a track or passageway for...

23 CFR 650.403 - Definition of terms.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., STRUCTURES, AND HYDRAULICS Highway Bridge Replacement and Rehabilitation Program § 650.403 Definition of... depression or an obstruction, such as water, a highway, or a railway, having a track or passageway for...

23 CFR 650.403 - Definition of terms.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., STRUCTURES, AND HYDRAULICS Highway Bridge Replacement and Rehabilitation Program § 650.403 Definition of... depression or an obstruction, such as water, a highway, or a railway, having a track or passageway for...

23 CFR 650.403 - Definition of terms.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., STRUCTURES, AND HYDRAULICS Highway Bridge Replacement and Rehabilitation Program § 650.403 Definition of... depression or an obstruction, such as water, a highway, or a railway, having a track or passageway for...

Assessing potential scour using the South Carolina bridge-scour envelope curves

USGS Publications Warehouse

Benedict, Stephen T.; Feaster, Toby D.; Caldwell, Andral W.

2016-09-30

SummaryBridge-scour equations presented in the Federal Highway Administration Hydraulic Engineering Circular No. 18 reflect the current state-of-the practice for predicting scour at bridges. Although these laboratory-derived equations provide an important resource for assessing scour potential, there is a measure of uncertainty when applying these equations to field conditions. The uncertainty and limitations have been acknowledged by laboratory researchers and confirmed in field investigations.Because of the uncertainty associated with bridge-scour equations, HEC-18 recommends that engineers evaluate the computed scour depths obtained from the equations and modify the resulting data if they appear unreasonable. Perhaps the best way to evaluate the reasonableness of predicted scour is to compare it to field measurements of historic scour. Historic field data show scour depths resulting from high flows and provide a reference for evaluating predicted scour. It is rare, however, that such data are available at or near a site of interest, making the evaluation of predicted scour as compared to field data difficult if not impossible. Realizing the value of historic scour measurements, the U.S. Geological Survey (USGS), in cooperation with the South Carolina Department of Transportation (SCDOT), conducted a series of three field investigations to collect historic scour data with the goal of understanding regional trends of scour at riverine bridges in South Carolina.Historic scour measurements, including measurements of clear-water abutment, contraction, and pier scour, as well as live-bed contraction and pier scour, were made at more than 200 bridges. These field investigations provided valuable insights into regional scour trends and yielded regional bridge-scour envelope curves that can be used as supplementary tools for assessing all components of scour at riverine bridges in South Carolina.The application and limitations of these envelope curves were documented in four reports. Because each report addresses different components of bridge scour, it was recognized that there was a need to develop an integrated procedure for applying the envelope curves to help assess scour potential at riverine bridges in South Carolina. The result of that effort is detailed in Benedict and others (2016) and summarized in this fact sheet.

Colonic stenting as bridge to surgery versus emergency surgery for management of acute left-sided malignant colonic obstruction: a multicenter randomized trial (Stent-in 2 study)

PubMed Central

van Hooft, Jeanin E; Bemelman, Willem A; Breumelhof, Ronald; Siersema, Peter D; Kruyt, Philip M; van der Linde, Klaas; Veenendaal, Roeland A; Verhulst, Marie-Louise; Marinelli, Andreas W; Gerritsen, Josephus JGM; van Berkel, Anne-Marie; Timmer, Robin; Grubben, Marina JAL; Scholten, Pieter; Geraedts, Alfons AM; Oldenburg, Bas; Sprangers, Mirjam AG; Bossuyt, Patrick MM; Fockens, Paul

2007-01-01

Background Acute left-sided colonic obstruction is most often caused by malignancy and the surgical treatment is associated with a high mortality and morbidity rate. Moreover, these operated patients end up with a temporary or permanent stoma. Initial insertion of an enteral stent to decompress the obstructed colon, allowing for surgery to be performed electively, is gaining popularity. In uncontrolled studies stent placement before elective surgery has been suggested to decrease mortality, morbidity and number of colostomies. However stent perforation can lead to peritoneal tumor spill, changing a potentially curable disease in an incurable one. Therefore it is of paramount importance to compare the outcomes of colonic stenting followed by elective surgery with emergency surgery for the management of acute left-sided malignant colonic obstruction in a randomized multicenter fashion. Methods/design Patients with acute left-sided malignant colonic obstruction eligible for this study will be randomized to either emergency surgery (current standard treatment) or colonic stenting as bridge to elective surgery. Outcome measurements are effectiveness and costs of both strategies. Effectiveness will be evaluated in terms of quality of life, morbidity and mortality. Quality of life will be measured with standardized questionnaires (EORTC QLQ-C30, EORTC QLQ-CR38, EQ-5D and EQ-VAS). Morbidity is defined as every event leading to hospital admission or prolonging hospital stay. Mortality will be analyzed as total mortality as well as procedure-related mortality. The total costs of treatment will be evaluated by counting volumes and calculating unit prices. Including 120 patients on a 1:1 basis will have 80% power to detect an effect size of 0.5 on the EORTC QLQ-C30 global health scale, using a two group t-test with a 0.05 two-sided significance level. Differences in quality of life and morbidity will be analyzed using mixed-models repeated measures analysis of variance. Mortality will be compared using Kaplan-Meier curves and log-rank statistics. Discussion The Stent-in 2 study is a randomized controlled multicenter trial that will provide evidence whether or not colonic stenting as bridge to surgery is to be performed in patients with acute left-sided colonic obstruction. Trial registration Current Controlled Trials ISRCTN46462267. PMID:17608947

[Neoplasic colonic obstruction: resolution with self-expanding metallic stents].

PubMed

Jury, Gastón; Amieva, Leandro; Dolan, Martín; Fagalde, Rafael López; Naiderman, Diego; Pastorino, Martín; Jury, Rubén

2014-03-01

The endoscopic placement of self-expanding metallic stents (SEMS) emerges as a therapeutic option for neoplastic colonic obstruction in two situations: as palliative treatment and as a bridge to surgery. The latter can avoid emergency surgery, thus decreasing the rate of ostomies and the mortality and morbidity associated with them. To evaluate the feasibility, safety and benefits of SEMS placement for the treatment of neoplastic colorectal obstruction. Between August 2008 and June 2012, we included in this prospective, longitudinal, descriptive and observational study all the patients suffering from colorectal neoplasia who were subjected to SEMS placement by the same group ofendoscopists. Nitinol SEMS were inserted under endoscopic vision and radioscopic control. Twenty seven SEMS were inserted in 27 patients, 61% of them were male and the average age was 70 years old. Symptoms of colonic suboclussion or obstruction were found in 92% of patients, 88% of the lesions were located in the left-side colon, 41% of cases were performed on an ambulatory basis and 65% of stenting was carried out for palliative purposes. The average time of hospitalization was 6,46 days. Technical and clinical success were 93% and 100%, respectively. Minor complications were observed in 11% of patients. Colonic stenting was followed by elective surgery within one month, by a laparoscopic technique in most cases. The placement of SEMS arises as a safe and effective alternative to palliative surgery or as a bridge to elective surgery.

Endoscopic stenting as bridge-to-surgery (BTS) in left-sided obstructing colorectal cancer: Experience with conformable stents.

PubMed

Parodi, Andrea; De Ceglie, Antonella; De Luca, Luca; Conigliaro, Rita; Naspetti, Riccardo; Arpe, Paola; Coccia, Gianni; Conio, Massimo

2016-11-01

Compared to emergency surgery, self-expandable metallic stents are effective and safe when used as bridge-to-surgery (BTS) in operable patients with acute colorectal cancer obstruction. In this study, we report data on the new conformable colonic stents. To evaluate clinical effectiveness of conformable stents as BTS in patients with acute colorectal cancer obstruction. This was a retrospective study. The study was conducted at six Italian Endoscopic Units. Data about patients with acute malignant colorectal obstruction were collected between 2007 and 2012. All patients were treated with conformable stents as BTS. Technical success, clinical success, rate of primary anastomosis and colostomy, early and late complications were evaluated. Data about 88 patients (62 males) were reviewed in this study. Conformable SEMS were correctly deployed in 86 out of 88 patients, with resolution of obstruction in all treated patients. Tumor resection with primary anastomosis was possible in all patients. A temporary colostomy was performed in 40. Early complications did not occur. Late complications occurred in 11 patients. Stent migration was significantly higher in patients treated with partially-covered stents compared to the uncovered group (35% vs. 0%, P<0.001). Endoscopical re-intervention was required in 12% of patients. One patient with rectal cancer had an anastomotic dehiscence after surgery and he was successfully treated with endoscopic clipping. One year after surgery, all patients were alive and local recurrence have not been documented. This was a retrospective and uncontrolled study. Preliminary data from this large case series are encouraging, with a high rate of technical and clinical success and low rate of clinically relevant complications. Partially-covered SEMS should be avoided in order to reduce the risk of endoscopic re-intervention. Copyright © 2016. Published by Elsevier Masson SAS.

Fluoroscopically guided placement of self-expandable metallic stents and stent-grafts in the treatment of acute malignant colorectal obstruction.

PubMed

Kim, Honsoul; Kim, Seung Hyoung; Choi, Sun Young; Lee, Kwang-Hun; Won, Jong Yoon; Lee, Do Yun; Lee, Jong Tae

2008-12-01

To evaluate the technical feasibility and clinical effectiveness of fluoroscopically guided placement of self-expandable metallic stents and stent-grafts for acute malignant colorectal obstruction. Radiologic images and clinical reports of 42 patients (22 men, 20 women; age range, 28-93 years; median age, 65.5 years) who underwent fluoroscopically guided colorectal stent insertion without endoscopic assistance for acute malignant obstruction were reviewed retrospectively. Eighteen patients received bare stents as a bridge to surgery. Twenty-four patients received 27 insertions of either a bare stent (n = 15) or a stent-graft (n = 12) for palliation. The obstruction was located in the rectum (n = 8), sigmoid (n = 17), descending colon (n = 8), splenic flexure (n = 3), and transverse colon (n = 6). Clinical success, defined as more than 50% dilatation of the stent with subsequent symptomatic improvement, was achieved in 41 of the 42 patients (98%). No major procedure-related complications occurred. Minor complications occurred in eight of the 45 procedures (18%). No perioperative mortalities occurred within 1 month after surgery. In the palliative group, the median stent patency was 62 days (range, 0-1,014 days). There was no statistically significant difference in stent patency between the bare stents (range, 0-855 days; median, 68 days) and stent-grafts (range, 1-1,014 days; median, 81 days). Fluoroscopically guided placement of self-expandable metallic stents and stent-grafts for the relief of acute malignant colorectal obstruction was technically feasible without endoscopic assistance-even in lesions proximal to the splenic flexure and transverse colon-and clinically effective in both bridge to surgery and palliative management.

Obstructive Left Colon Cancer Should Be Managed by Using a Subtotal Colectomy Instead of Colonic Stenting

PubMed Central

Min, Chung Ki; Lee, Donghyoun; Jung, Kyung Uk; Lee, Sung Ryol; Kim, Hungdai; Chun, Ho-Kyung

2016-01-01

Purpose This study compared a subtotal colectomy to self-expandable metallic stent (SEMS) insertion as a bridge to surgery for patients with left colon-cancer obstruction. Methods Ninety-four consecutive patients with left colon-cancer obstruction underwent an emergency subtotal colectomy or elective SEMS insertion between January 2007 and August 2014. Using prospectively collected data, we performed a retrospective comparative analysis on an intention-to-treat basis. Results A subtotal colectomy and SEMS insertion were attempted in 24 and 70 patients, respectively. SEMS insertion technically failed in 5 patients (7.1%). The mean age and rate of obstruction in the descending colon were higher in the subtotal colectomy group than the SEMS group. Sex, underlying disease, American Society of Anesthesiologists physical status, and pathological stage showed no statistical difference. Laparoscopic surgery was performed more frequently in patients in the SEMS group (62 of 70, 88.6%) than in patients in the subtotal colectomy group (4 of 24, 16.7%). The overall rate of postoperative morbidity was higher in the SEMS group. No Clavien-Dindo grade III or IV complications occurred in the subtotal colectomy group, but 2 patients (2.9%) died from septic complications in the SEMS group. One patient (4.2%) in the subtotal colectomy group had synchronous cancer. The total hospital stay was shorter in the subtotal colectomy group. The median number of bowel movements in the subtotal colectomy group was twice per day at postoperative 3–6 months. Conclusion A subtotal colectomy for patients with obstructive left-colon cancer is a clinically and oncologically safer, 1-stage, surgical strategy compared to SEMS insertion as a bridge to surgery. PMID:28119864

A prospective multicenter study on self-expandable metallic stents as a bridge to surgery for malignant colorectal obstruction in Japan: efficacy and safety in 312 patients.

PubMed

Saito, Shuji; Yoshida, Shuntaro; Isayama, Hiroyuki; Matsuzawa, Takeaki; Kuwai, Toshio; Maetani, Iruru; Shimada, Mamoru; Yamada, Tomonori; Tomita, Masafumi; Koizumi, Koichi; Hirata, Nobuto; Kanazawa, Hideki; Enomoto, Toshiyuki; Sekido, Hitoshi; Saida, Yoshihisa

2016-09-01

Endoscopic stenting with a self-expandable metallic stent (SEMS) is a widely accepted procedure for malignant colonic obstruction. The Colonic Stent Safe Procedure Research Group conducted the present prospective feasibility study. Our objectives were to estimate the safety and feasibility of SEMS placement as a bridge to surgery (BTS) for malignant colorectal obstruction. We conducted a prospective, observational, single-arm, multicenter clinical trial from March 2012 to October 2013. Each patient was treated with an uncovered WallFlex enteral colonic stent. Patients were followed up until discharge after surgery. A total of 518 consecutive patients were enrolled in this study. The cohort intended for BTS consisted of 312 patients (61 %), and the stent could be released in 305 patients. Technical and clinical success rates were 98 and 92 %, respectively. Elective surgery was performed in 297 patients, and emergency surgery was performed in eight patients for the treatment of complications. The overall preoperative complication rate was 7.2 %. Major complications, including perforation, occurred in 1.6 %, persistent colonic obstruction occurred in 1.0 %, and stent migration occurred in 1.3 % patients. The median time from SEMS to surgery was 16 days. Silent perforations were observed in 1.3 %. Open and laparoscopic surgery was performed in 121 and 184 patients, respectively. The tumor could be resected in 297 patients. The primary anastomosis rate was 92 %. The rate of anastomotic leakage was 4 %, and the overall stoma creation rate was 10 %. The median duration of hospitalization following surgery was 12 days. Overall postoperative morbidity and mortality rates were 16 and 0.7 %, respectively. This largest, multicenter, prospective study demonstrates the feasibility of SEMS placement as a BTS for malignant colorectal obstruction. SEMS serves as a safe and effective BTS with acceptable stoma creation and complication rates in patients with acute malignant colonic obstruction.

Management of large bowel obstruction with self-expanding metal stents. A multicentre retrospective study of factors determining outcome.

PubMed

Geraghty, J; Sarkar, S; Cox, T; Lal, S; Willert, R; Ramesh, J; Bodger, K; Carlson, G L

2014-06-01

UK cancer guidelines recommend patients with colonic obstruction due to suspected malignancy be considered for stenting with a self-expanding metal stent (SEMS). Considerable variation in practice exists due to a lack of expertise, technical difficulties and other, as yet ill-defined features. This retrospective multi-centre study aims to determine the outcome following colonic stenting for large bowel obstruction and identify factors associated with successful intervention. A regional programme of colonic stenting for large bowel obstruction, in five UK centres from 2005 to 2010 was evaluated for outcome including technical and clinical success, survival, complications and reoperation. A SEMS was inserted in 334 patients, including 264 (79.0%) for palliation and 52 (15.6%) as a bridge to surgery. Technical success was achieved in 292 (87.4%) patients, with 46 (13.8%) experiencing a complication or technical failure. Reoperation was required in 39 (14.8%) patients stented for palliation of colorectal cancer of whom 16 (6.1%) subsequently required a colostomy. A one-stage primary anastomosis was achieved in 35 (67.3%) of the 52 patients undergoing stenting as a bridge to resection. Technical success did not vary by indication or site of obstruction (P = 0.60) but was higher for operators who had performed more than 10 procedures (OR 3.34, P = 0.001). ASA grade ≥3 predicted a worse clinical outcome (OR 0.43, P = 0.04). The through-the-scope (TTS) endoscopy technique was more successful than radiological placement alone (90.3% vs 74.8%, P < 0.001). Experienced operators using a TTS technique achieved a better outcome for the emergency management of large bowel obstruction. Older, sicker patients and those with extracolonic and benign strictures fared less well. Colorectal Disease © 2014 The Association of Coloproctology of Great Britain and Ireland.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kanasaki, Shuzo; Furukawa, Akira; Kane, Teruyuki

Purpose: To evaluate the clinical efficacy of the polyure-thane-covered Nitinol Strecker stent in the treatment of patients with malignant biliary obstruction.Methods: Twenty-three covered stents produced by us were placed in 18 patients with malignant biliary obstruction. Jaundice was caused by cholangiocarcinoma (n=5), pancreatic Cancer (n=6), gallbladder Cancer (n=4), metastatic lymph nodes (n=2), and tumor of the papilla (n=1).Resulrs: The mean patency period of the Stents was 37.5 weeks (5-106 weeks). Recurrent obstructive jaundice occurred in two patients (11%). Adequate biliary drainage over 50 weeks or until death was achieved in 17 of 18 patients (94.4%). Late cholangitis was observed inmore » two patients whose stents bridged the ampulla of Vater. Other late severe complications were not encountered.Conclusion: Although more study is necessary, our results suggest the clinical efficacy of our covered Nitinol Strecker stent in the management of obstructive jaundice caused by malignant diseases.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kanasaki, Shuzo; Furukawa, Akira; Kane, Teruyuki

Purpose: To evaluate the clinical efficacy of the polyurethane-covered Nitinol Strecker stent in the treatment of patients with malignant biliary obstruction.Methods: Twenty-three covered stents produced by us were placed in 18 patients with malignant biliary obstruction. Jaundice was caused by cholangiocarcinoma (n = 5), pancreatic cancer (n = 6), gallbladder cancer (n = 4), metastatic lymph nodes (n = 2), and tumor of the papilla (n 1).Results: The mean patency period of the stents was 37.5 weeks (5-106 weeks). Recurrent obstructive jaundice occurred in two patients (11%). Adequate biliary drainage over 50 weeks or until death was achieved in 17more » of 18 patients (94.4%). Late cholangitis was observed in two patients whose stents bridged the ampulla of Vater. Other late severe complications were not encountered.Conclusion: Although more study is necessary, our results suggest the clinical efficacy of our covered Nitinol Strecker stent in the management of obstructive jaundice caused by malignant diseases.« less

A pilot study about the oncologic safety of colonic self-expandable metal stents (SEMS) in obstructive colon cancer: is occlusion always better than "silent" perforation?

PubMed

Zanghì, A; Piccolo, G; Cavallaro, A; Pulvirenti, E; Lo Menzo, E; Cardì, F; Di Vita, M; Cappellani, A

2016-12-01

To evaluate the oncologic safety of colonic self-expandable metal stents (SEMS) in obstructive colon cancer. We retrospectively reviewed all the patients who were treated with endoscopic placement of a self-expandable metallic stent (SEMS) at our institution. A total of 26 patients were identified during the study period, of which 24 patients (92.30%) were treated with SEMS as a bridge-to-surgery and 2 (7.69%) as palliation. In 22 cases (80.76%), the stenosis was localized to the left side. Clinical success with resolution of bowel obstructions was achieved in 22 (84.61%) patients within a short period of time. Among patients treated successfully with SEMS insertion as bridge to surgery (n = 22), 20 (90.9%) underwent one-stage surgery with primary anastomosis while 2 patients (9.09%) underwent colostomy due to intraoperative evidence of a covered perforation by cancer tissue in the pelvis. Patients with subclinical perforation developed an early peritoneal carcinomatosis, 10 patients treated with curative intent subsequently developed liver metastasis after 24 months. We reported an overall poor outcome among patients treated with the insertion of SEMS. This led us to think that, in some cases, occlusion may be better than a "silent" perforation.

A comparative study of short- and medium-term outcomes comparing emergent surgery and stenting as a bridge to surgery in patients with acute malignant colonic obstruction.

PubMed

Kavanagh, Dara O; Nolan, Blathnaid; Judge, Ciaran; Hyland, John M P; Mulcahy, Hugh E; O'Connell, P Ronan; Winter, Des C; Doherty, Glen A

2013-04-01

The use of self-expanding metal stents as a bridge to surgery in the setting of malignant colorectal obstruction has been advocated as an acceptable alternative to emergency surgery. However, concerns about the safety of stenting have been raised following recent randomized studies. The aim of the current study was to compare outcomes. This was an observational, comparative study. This study was conducted at a tertiary referral center and university teaching hospital. Patients with malignant colonic obstruction (n = 49) treated by either emergency surgery (n = 26) or with stent placement (n = 23) as a bridge to surgery were identified and followed. Short-term outcomes including stoma rates and postoperative morbidity and medium-term oncological outcomes were compared based on an "intention-to-treat" analysis. Patients in both groups were well matched on clinicopathological parameters. Technical and clinical successful stent deployment was achieved in 91% and 83%. This did not adversely impact cancer-specific and overall survival (log rank = nonsignificant). No difference was observed in stoma rates, primary anastomosis rates, perioperative mortality rates, or reoperation rates between the 2 groups. Significantly fewer patients underwent total colectomy in the stent group in comparison with the emergency surgery group (1/23 vs 6/26: p = 0.027). There was no difference in postoperative morbidity (59% vs 66%: p = 0.09). There was a significant reduction in readmission rates in the stent group (5/26 vs 0/23: p = 0.038). The small sample size of this study could lead to type II error. In addition, the study was nonrandomized and demonstrated a limited length of follow-up. Despite a high rate of technical and clinical success in selected patients with colonic obstruction, stenting has no impact on stoma rates. Despite concerns about the rate of stent-associated perforation, stenting does not adversely impact disease progression or survival. Future comparative trials are essential to better define the role of stenting in this setting and to ensure that we are not using costly technology to create an elective operative situation without concomitant patient benefits.

23 CFR 650.305 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.305 Definitions. Terms used in this... structure including supports erected over a depression or an obstruction, such as water, highway, or railway...(a)(11). In-depth inspection. A close-up, inspection of one or more members above or below the water...

23 CFR 650.305 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.305 Definitions. Terms used in this... structure including supports erected over a depression or an obstruction, such as water, highway, or railway...(a)(11). In-depth inspection. A close-up, inspection of one or more members above or below the water...

23 CFR 650.305 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.305 Definitions. Terms used in this... structure including supports erected over a depression or an obstruction, such as water, highway, or railway...(a)(11). In-depth inspection. A close-up, inspection of one or more members above or below the water...

23 CFR 650.305 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.305 Definitions. Terms used in this... structure including supports erected over a depression or an obstruction, such as water, highway, or railway...(a)(11). In-depth inspection. A close-up, inspection of one or more members above or below the water...

47 CFR 8.7 - No unreasonable discrimination.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.7 No unreasonable discrimination. A person engaged in the provision of fixed broadband Internet access service, insofar as such... consumer's broadband Internet access service. Reasonable network management shall not constitute...

47 CFR 8.7 - No unreasonable discrimination.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.7 No unreasonable discrimination. A person engaged in the provision of fixed broadband Internet access service, insofar as such... consumer's broadband Internet access service. Reasonable network management shall not constitute...

47 CFR 8.7 - No Unreasonable Discrimination.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.7 No Unreasonable Discrimination. A person engaged in the provision of fixed broadband Internet access service, insofar as such... consumer's broadband Internet access service. Reasonable network management shall not constitute...

Interventional and surgical therapeutic strategies for pulmonary arterial hypertension: Beyond palliative treatments.

PubMed

Sandoval, Julio; Gomez-Arroyo, Jose; Gaspar, Jorge; Pulido-Zamudio, Tomas

2015-10-01

Despite significant advances in pharmacological treatments, pulmonary arterial hypertension remains an incurable disease with an unreasonably high morbidity and mortality. Although specific pharmacotherapies have shifted the survival curves of patients and improved exercise endurance as well as quality of life, it is also true that these pharmacological interventions are not always accessible (particularly in developing countries) and, perhaps most importantly, not all patients respond similarly to these drugs. Furthermore, many patients will continue to deteriorate and will eventually require an additional, non-pharmacological, intervention. In this review we analyze the role of atrial septostomy and Potts anastomosis in the management of patients with pulmonary arterial hypertension, we summarize the current worldwide clinical experience (case reports and case series), and discuss why these interventional/surgical strategies might have a therapeutic role beyond that of a "bridge" to transplantation. Copyright © 2015 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

14 CFR 399.36 - Unreasonable discrimination.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Unreasonable discrimination. 399.36 Section 399.36 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION... the discrimination; and (4) Actual and potential competitive forces cannot reliably be expected to...

14 CFR 399.36 - Unreasonable discrimination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Unreasonable discrimination. 399.36 Section 399.36 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION... the discrimination; and (4) Actual and potential competitive forces cannot reliably be expected to...

Suicide right ventricle after lung transplantation for pulmonary vascular disease.

PubMed

Gangahanumaiah, Shivanand; Scarr, Bronwyn C; Buckland, Mark R; Pilcher, David V; Paraskeva, Miranda A; McGiffin, David C

2018-06-19

A 27-year-old female with Eisenmenger's syndrome underwent closure of a patent ductus arteriosus, closure of a perimembranous ventricular septal defect and mid muscular defect and bilateral lung transplantation. Her immediate postoperative course was complicated by severe right ventricular outflow tract (RVOT) obstruction resulting in hemodynamic collapse, a condition described as suicide right ventricle. The patient was placed on central Veno-Arterial Extra-Corporeal Membrane Oxygenation as a bridge to the relief of RVOT obstruction which included a right ventricular outflow muscle resection and a right ventricle outflow tract patch. The patient made an uneventful recovery. © 2018 Wiley Periodicals, Inc.

Perceived Parental Authority: Reasonable and Unreasonable.

ERIC Educational Resources Information Center

Harris, Irving D.; Howard, Kenneth I.

1981-01-01

This questionnaire study investigated personality phenomena in adolescents who described their parents along two dimensions: exercise of family authority and reasonableness. The main area of analysis concerned the extent to which male and female adolescents react differently to reasonable or unreasonable paternal and maternal authority. (Author/GK)

40 CFR 172.57 - Submission of information regarding potential unreasonable adverse effects.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Submission of information regarding potential unreasonable adverse effects. 172.57 Section 172.57 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS EXPERIMENTAL USE PERMITS Notification for Certain...

Laser prostatectomy with side-firing Albarran bridge

NASA Astrophysics Data System (ADS)

Mattioli, Stefano

1996-01-01

Laser ablation of the prostatic tissue or laser prostatectomy, is used as an alternative method to traditional endoscopic resection of the prostate (TURP). Recently, there have been reports of transurethral coagulation of the prostate using various sidefiring laser systems. These devices can be classified into two groups: one that uses total internal reflection, and one that has a gold-plated metal reflecting mirror. We have developed a new Albarran bridge with these characteristics in order to minimize the restrictions presented by the other delivery systems. Laser coagulation of the prostate has been performed using a conventional bare fiber passed through a sidefiring Albarran bridge containing a distal gold-plated reflector with a deflecting mechanism. The complete device passes through a 21 F. rigid cystourethroscope. The system and the fiber can be used for several dozen treatments. Transurethral laser coagulation was performed on 65 patients for obstructive symptoms caused by begnin prostatic hyperplasia. The dosimetry was 1000 J per 1cc of prostatic tissue at 60 W for 60 seconds. Successful results were obtained in 55 patients (85%). A significant reduction in obstructive symptoms from a mean AUA-6 Symptom Score of 21.2 preoperatively to 9.1 at 3 months and 7.6 at 6 months was associated with an increase in the peak urine flow rate from 6.1 mL/sec preoperatively to 13.1 mL/sec at 3 months and 15.7 mL/sec at 6 months. The residual urine volume averaged 190 mL preoperatively and 365 mL at 6 months. Transurethral laser coagulation of the prostate represents a useful alternative to transurethral resection, especially in high-risk patients with an enlarged median lobe or a small prostate. Treatment is bloodless and, with the aid of the modified Albarran bridge, can be performed with standard urological instrumentation and conventional Nd:YAG laser system. The new Albarran bridge also can reduce the cost of laser treatment.

Acute resection versus bridge to surgery with diverting colostomy for patients with acute malignant left sided colonic obstruction: Systematic review and meta-analysis.

PubMed

Amelung, Femke J; Mulder, Charlotte L J; Verheijen, Paul M; Draaisma, Werner A; Siersema, Peter D; Consten, Esther C J

2015-12-01

Currently, no consensus exists on the best treatment strategy for acute malignant left-sided colonic obstruction. This systematic review and meta-analysis aims to compare the outcomes following the two surgical treatment options; primary resection versus colostomy creation as bridge to surgery. This systematic review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to minimize risk of bias. Pubmed, Embase and Cochrane Library were searched for all relevant literature. Methodological quality of included studies was assessed using the MINORS criteria. Pooled odds ratios with 95% confidence intervals (95%CI) were calculated using random effects models. Eight comparative studies were included, reporting on 2424 patients; 1973 patients were treated with primary resection and 451 patients with colostomy construction followed by elective resection. Meta-analysis showed no significant differences between both treatment groups regarding 30-day mortality and morbidity (OR = 0.77, 95%CI 0.3-1.96 and OR = 0.76, 95%CI 0.51-1.13, respectively). However, patients treated with a colostomy followed by elective resection had significantly more primary anastomoses constructed and were less likely to be left with a permanent colostomy (OR = 0.17, 95%CI 0.11-0.26 and OR = 0.22, 95%CI 0.11-0.46, respectively). This systematic review provides an overview of all available literature on primary resection versus colostomy creation as bridge to surgery in patients with acute LSCO. Keeping the limitations of this study in mind, we conclude that a diverting colostomy as bridge to surgery is a safe and valid alternative for primary resection. Copyright © 2015 Elsevier Ltd. All rights reserved.

Mathematics as an Instigator of Scientific Revolutions

ERIC Educational Resources Information Center

Brush, Stephen G.

2015-01-01

In a famous 1960 paper, Wigner discussed "The Unreasonable Effectiveness of Mathematics in the Natural Sciences." I suggest that the effectiveness of mathematics in producing successful new theories and surprising discoveries is even more unreasonable than Wigner claimed. In this paper, I present several historical case studies to…

40 CFR 125.122 - Determination of unreasonable degradation of the marine environment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Determination of unreasonable degradation of the marine environment. 125.122 Section 125.122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS FOR THE NATIONAL POLLUTANT DISCHARGE...

40 CFR 125.122 - Determination of unreasonable degradation of the marine environment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Determination of unreasonable degradation of the marine environment. 125.122 Section 125.122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS FOR THE NATIONAL POLLUTANT DISCHARGE...

40 CFR 125.122 - Determination of unreasonable degradation of the marine environment.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Determination of unreasonable degradation of the marine environment. 125.122 Section 125.122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS FOR THE NATIONAL POLLUTANT DISCHARGE...

20 CFR Appendix A to Part 617 - Standard for Claim Filing, Claimant Reporting, Job Finding, and Employment Services

Code of Federal Regulations, 2011 CFR

2011-04-01

... expenditure of an unreasonable amount of time or money in traveling to the nearest facility established by the... and coordinate the contacts required of a claimant as not to place an unreasonable burden on him or...

75 FR 38521 - Registration Review; Biopesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... adverse human health impacts or environmental effects from exposure to the pesticides discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... perform its intended function without unreasonable adverse effects on human health or the environment...

75 FR 60117 - Registration Review; Biopesticides Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... adverse human health impacts or environmental effects from exposure to the pesticides discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... its intended function without unreasonable adverse effects on human health or the environment...

77 FR 74479 - Registration Review; Pesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-14

... adverse human health impacts or environmental effects from exposure to the pesticides discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... function without unreasonable adverse effects on human health or the environment. Registration review...

77 FR 59188 - Registration Review; Pesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-26

... adverse human health impacts or environmental effects from exposure to the pesticide(s) discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... without unreasonable adverse effects on human health or the environment. Registration review dockets...

40 CFR 125.122 - Determination of unreasonable degradation of the marine environment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Determination of unreasonable degradation of the marine environment. 125.122 Section 125.122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS FOR THE NATIONAL POLLUTANT DISCHARGE...

40 CFR 125.122 - Determination of unreasonable degradation of the marine environment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Determination of unreasonable degradation of the marine environment. 125.122 Section 125.122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS FOR THE NATIONAL POLLUTANT DISCHARGE...

Unreasonable Compensation: The Hidden Issue in the IRS College and University Examination Guidelines.

ERIC Educational Resources Information Center

Harding, Bertrand M., Jr.; McClellan, Edgar D.

1993-01-01

Issues in Internal Revenue Service (IRS) guidelines for financial audit of colleges and universities that relate specifically to the institution's compensation of officers, directors, and employees are discussed. Institutions are advised that the "unreasonable compensation" issue may be raised, and they should review compensation…

47 CFR 64.4005 - Unreasonable terms or conditions on the provision of customer account information.

Code of Federal Regulations, 2010 CFR

2010-10-01

... provision of customer account information. 64.4005 Section 64.4005 Telecommunication FEDERAL COMMUNICATIONS... Customer Account Record Exchange Requirements § 64.4005 Unreasonable terms or conditions on the provision of customer account information. To the extent that a carrier incurs costs associated with providing...

Student Privacy Rights Involving Strip Searches

ERIC Educational Resources Information Center

Essex, Nathan L.

2005-01-01

The Fourth Amendment to the US Constitution provides protection of all citizens against unreasonable search and seizure. The US Supreme Court has affirmed that the basic purpose of the Fourth Amendment is to safeguard the privacy and security of individuals against unreasonable intrusive searches by governmental officials. Since students possess…

78 FR 33393 - Petition Requesting a Ban or Standard on Adult Portable Bed Rails

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

... Standard on Adult Portable Bed Rails AGENCY: Consumer Product Safety Commission. ACTION: Notice. SUMMARY... adult portable bed rails pose an unreasonable risk of injury and initiate related rulemaking under... that adult portable bed rails pose an unreasonable risk of injury and initiate related rulemaking under...

40 CFR 55.7 - Exemptions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... infeasible or will cause an unreasonable threat to health and safety. (b) Request for an exemption—(1) Permit... technically infeasible or would cause an unreasonable threat to health and safety. (ii) The request shall... delegated agency, the Minerals Management Service, and the U.S. Coast Guard reach a consensus decision on...

40 CFR 90.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2011 CFR

2011-07-01

... cause or contribute to an unreasonable risk to public health, welfare, or safety in its operation or... that cause or contribute to an unreasonable risk to public health, welfare, or safety while operating... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Requirement of certification...

40 CFR 90.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2013 CFR

2013-07-01

... cause or contribute to an unreasonable risk to public health, welfare, or safety in its operation or... that cause or contribute to an unreasonable risk to public health, welfare, or safety while operating... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Requirement of certification...

40 CFR 90.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2014 CFR

2014-07-01

... cause or contribute to an unreasonable risk to public health, welfare, or safety in its operation or... that cause or contribute to an unreasonable risk to public health, welfare, or safety while operating... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Requirement of certification-prohibited...

40 CFR 91.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2013 CFR

2013-07-01

... contribute to an unreasonable risk to public health, welfare, or safety in its operation or function. (b) You... or contribute to an unreasonable risk to public health, welfare, or safety while operating. For... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Requirement of certification...

40 CFR 90.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2012 CFR

2012-07-01

... cause or contribute to an unreasonable risk to public health, welfare, or safety in its operation or... that cause or contribute to an unreasonable risk to public health, welfare, or safety while operating... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Requirement of certification...

40 CFR 91.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2010 CFR

2010-07-01

... contribute to an unreasonable risk to public health, welfare, or safety in its operation or function. (b) You... or contribute to an unreasonable risk to public health, welfare, or safety while operating. For... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Requirement of certification...

40 CFR 91.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2011 CFR

2011-07-01

... contribute to an unreasonable risk to public health, welfare, or safety in its operation or function. (b) You... or contribute to an unreasonable risk to public health, welfare, or safety while operating. For... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Requirement of certification...

40 CFR 90.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2010 CFR

2010-07-01

... cause or contribute to an unreasonable risk to public health, welfare, or safety in its operation or... that cause or contribute to an unreasonable risk to public health, welfare, or safety while operating... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Requirement of certification...

40 CFR 91.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2012 CFR

2012-07-01

... contribute to an unreasonable risk to public health, welfare, or safety in its operation or function. (b) You... or contribute to an unreasonable risk to public health, welfare, or safety while operating. For... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Requirement of certification...

78 FR 14403 - Alabama Metal Coil Securement Act; Petition for Determination of Preemption

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... benefit; (2) are incompatible with Federal regulations; or (3) would cause an unreasonable burden on interstate commerce. FMCSA has determined that there is insufficient support for the claimed safety benefits... safety benefits and do not place an unreasonable burden on interstate commerce. Applicable Law Section...

40 CFR 152.46 - Notification and non-notification changes to registrations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... cause unreasonable adverse effects to the environment may be accomplished by notification to the Agency... having no potential to cause unreasonable adverse effects to the environment may be accomplished without... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Notification and non-notification...

40 CFR 761.62 - Disposal of PCB bulk product waste.

Code of Federal Regulations, 2010 CFR

2010-07-01

... methods or locations will not pose an unreasonable risk or injury to health or the environment. EPA may... method will not pose an unreasonable risk of injury to health or the environment. (d) Disposal as daily.... 761.62 Section 761.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC...

77 FR 40048 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... adverse human health impacts or environmental effects from exposure to the pesticide(s) discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... its intended function without unreasonable adverse effects on human health or the environment...

77 FR 18810 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Act

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

... adverse human health impacts or environmental effects from exposure to the pesticide(s) discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... its intended function without unreasonable adverse effects on human health or the environment...

75 FR 35810 - Registration Review; Pesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticides... can still be used without unreasonable adverse effects on human health or the environment. A pesticide... function without unreasonable adverse effects on human health or the environment. Registration review...

75 FR 60119 - Registration Review; Antimicrobial Pesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticides... can still be used without unreasonable adverse effects on human health or the environment. A pesticide... its intended function without unreasonable adverse effects on human health or the environment...

76 FR 38166 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-29

... adverse human health impacts or environmental effects from exposure to the pesticides discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... perform its intended function without unreasonable adverse effects on human health or the environment...

Development and Validation of the Family Beliefs Inventory: A Measure of Unrealistic Beliefs among Parents and Adolescents.

ERIC Educational Resources Information Center

Roehling, Patricia Vincent; Robin, Arthur L.

1986-01-01

Evaluated the criterion-related validity of the Family Beliefs Inventory, a new self-report measure of unreasonable beliefs regarding parent-adolescent relationships. Distressed fathers displayed more unreasonable beliefs concerning ruination, obedience, perfectionism, and malicious intent than nondistressed fathers. Distressed adolescents…

40 CFR 172.10 - Refusals to issue and revocation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... permit is not justified, or that the issuance of such a permit would cause unreasonable adverse effects... conditions are inadequate to avoid unreasonable adverse effects on the environment, or if new evidence is obtained which demonstrates that the tolerance will be inadequate to protect the public health, or for...

Report: Close-Out of Hotline Complaint on Unreasonable Cost Increase to the Wastewater Treatment Facility Improvements, Perkins, Oklahoma

EPA Pesticide Factsheets

Report #12-X-0161, December 29, 2011. We have closed a hotline complaint that project costs increased unreasonably due to American Recovery and Reinvestment Act of 2009 (Recovery Act) requirements because we found no evidence to support the complaint.

Past, present, and future of endobronchial laser photoresection

PubMed Central

Khemasuwan, Danai; Wang, Ko-Pen

2015-01-01

Laser photoresection of central airway obstruction is a useful tool for an Interventional Pulmonologist (IP). Endobronchial therapy of the malignant airway obstruction is considered as a palliative measure or a bridge therapy to the definite treatment of cancer. Several ablative therapies such as electrocautery, argon plasma coagulation (APC), cryotherapy and laser photoresection exist in the armamentarium of IP to tackle such presentations. Besides Neodymium-Yttrium, Aluminum, Garnet (Nd:YAG) laser, there are several different types of laser that have been used by the pulmonologist with different coagulative and cutting properties. This chapter focuses on the historical perspective, current status, and potentials of lasers in the management of central airway lesions. PMID:26807285

Emergency management of acute colonic cancer obstruction.

PubMed

Gainant, A

2012-02-01

Emergency management of obstructing colonic cancer depends on both tumor location and stage, general condition of the patient and surgeon's experience. Right sided or transverse colon obstructing cancers are usually treated by right hemicolectomy-extended if necessary to the transverse colon-with primary anastomosis. For left-sided obstructing cancer, in patients with low surgical risk, primary resection and anastomosis associated with on-table irrigation or manual decompression can be performed. It prevents the confection of a loop colostomy but presents the risk of anastomotic leakage. Subtotal or total colectomy allows the surgeon to encompass distended and fecal-loaded colon, and to perform one-stage resection and anastomosis. Its disadvantage is an increased daily frequency of stools. It must be performed only in cases of diastatic colon perforation or synchronous right colonic cancer. In patients with high surgical risk, Hartmann procedure must be preferred. It allows the treatment of both obstruction and cancer, and prevents anastomotic leakage but needs a second operation to reverse the colostomy. Colonic stenting is clinically successful in up to 90% in specialized groups. It is used as palliation in patients with disseminated disease or bridge to surgery in the others. If stent insertion is not possible, loop colostomy is still indicated in patients at high surgical risk. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

76 FR 58784 - Bad Boy Enterprises, LLC, Provisional Acceptance of a Settlement Agreement and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-22

... unreasonable risk of serious injury or death, Bad Boy failed to inform the Commission immediately of such... product hazard or create an unreasonable risk of serious injury or death, and denies that it violated the... Order. Understandings, agreements, representations, or interpretations apart from those contained in the...

76 FR 79656 - E & B Giftware LLC, Provisional Acceptance of a Settlement Agreement and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-22

... product hazard, or created an unreasonable risk of serious injury or death, EB failed to immediately... product hazard or create an unreasonable risk of serious injury or death. Furthermore, it denies that it.... Understandings, agreements, representations, or interpretations apart from those contained in the Agreement and...

16 CFR 1115.12 - Information which should be reported; evaluating substantial product hazard.

Code of Federal Regulations, 2011 CFR

2011-01-01

... considered in determining whether a defect creates a substantial risk of injury. These factors are set forth... reportable noncompliance, defect or unreasonable risk. The obligation to report arises upon receipt of... could create a substantial product hazard, or unreasonable risk of serious injury or death. Thus, an...

16 CFR 1115.12 - Information which should be reported; evaluating substantial product hazard.

Code of Federal Regulations, 2010 CFR

2010-01-01

... considered in determining whether a defect creates a substantial risk of injury. These factors are set forth... reportable noncompliance, defect or unreasonable risk. The obligation to report arises upon receipt of... could create a substantial product hazard, or unreasonable risk of serious injury or death. Thus, an...

75 FR 80496 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-22

... high and adverse human health impacts or environmental effects from exposure to the pesticide(s... can still be used without unreasonable adverse effects on human health or the environment. A pesticide... perform its intended function without unreasonable adverse effects on human health or the environment...

78 FR 18586 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Acts

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-27

... adverse human health impacts or environmental effects from exposure to the pesticide(s) discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... perform its intended function without unreasonable adverse effects on human health or the environment...

Get even and feel good? Moderating effects of justice sensitivity and counterproductive work behavior on the relationship between illegitimate tasks and self-esteem.

PubMed

Schulte-Braucks, Julia; Baethge, Anja; Dormann, Christian; Vahle-Hinz, Tim

2018-04-23

We proposed that effects of illegitimate tasks, which comprise unreasonable and unnecessary tasks, on self-esteem and counterproductive work behavior (CWB) are enhanced among employees who are highly sensitive to injustice. CWB was further proposed to be a moderating coping strategy, which restores justice and buffers the detrimental effects of illegitimate tasks on self-esteem. In this study, 241 employees participated in a diary study over five workdays and a follow-up questionnaire one week later. Daily effects were determined in multilevel analyses: Unreasonable tasks decreased self-esteem and increased CWB the same day, especially among employees high in trait justice sensitivity. Unnecessary tasks only related to more CWB the same day, regardless of one's justice sensitivity. Weekly effects were determined in cross-lagged panel analyses: Unreasonable and unnecessary tasks increased CWB, and justice sensitivity moderated the effect of unreasonable tasks on CWB and of unnecessary tasks on self-esteem. Moderating effects of CWB were split: In daily analyses, CWB buffered the negative effects of illegitimate tasks. In weekly analyses, CWB enhanced the negative effects of illegitimate tasks. Overall, illegitimate tasks rather affected CWB than self-esteem, with more consistent effects for unreasonable than for unnecessary tasks. Thus, we confirm illegitimate tasks as a relevant work stressor with issues of injustice being central to this concept and personality having an influence on what is perceived as (il)legitimate. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Applicability, Indispensability, and Underdetermination: Puzzling over Wigner's "Unreasonable Effectiveness of Mathematics"

ERIC Educational Resources Information Center

Gelfert, Axel

2014-01-01

In his influential 1960 paper "The Unreasonable Effectiveness of Mathematics in the Natural Sciences", Eugene P. Wigner raises the question of why something that was developed without concern for empirical facts--mathematics--should turn out to be so powerful in explaining facts about the natural world. Recent philosophy of science has…

76 FR 37793 - Viking Range Corporation, Provisional Acceptance of a Settlement Agreement and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-28

... a substantial product hazard, or created an unreasonable risk of serious injury or death, Viking... unreasonable risk of serious injury or death, and denies that it violated the reporting requirements of Section..., representations or interpretations apart from those contained in the Agreement and the Order may not be used to...

26 CFR 1.534-1 - Burden of proof as to unreasonable accumulations generally.

Code of Federal Regulations, 2010 CFR

2010-04-01

... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Corporations Used to Avoid Income Tax on Shareholders § 1.534-1 Burden of proof as to unreasonable accumulations generally. For purposes of applying the... under section 535(c)(1), the burden of proof with respect to an allegation by the Commissioner that all...

77 FR 21564 - Agency Information Collection Activities; Proposed Collection; Comment Request; Administrative...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-10

... ownership if devices are detained at a place other than that of the appellant. Under Sec. 800.55(k), the... an unreasonable and substantial risk of illness or injury. Section 895.21 (21 CFR 895.21), on banned... the device presents substantial deception, unreasonable and substantial risk of illness or injury, or...

Palliative self-expandable metal stents for acute malignant colorectal obstruction: clinical outcomes and risk factors for complications.

PubMed

Han, Jae Pil; Hong, Su Jin; Kim, Shin Hee; Choi, Jong Hyo; Jung, Hee Jae; Cho, Youn Hee; Ko, Bong Min; Lee, Moon Sung

2014-08-01

Self-expandable metal stents (SEMSs) have been used as palliative treatment or bridge to surgery for obstructions caused by colorectal cancer (CRC). We assessed the long-term outcomes of palliative SEMSs and evaluated the risk factors influencing complications. One hundred and seventy-five patients underwent SEMS placement for acute malignant colorectal obstruction. Of the 72 patients who underwent palliative treatment for primary CRC, 30 patients received chemotherapy (CT) for primary cancer (CT group) and 42 underwent best supportive treatment (BST) without CT (BST group). There was a significant difference in late migration between the CT group and the BST group (20.0% in CT group, 2.4% in BST group, p = 0.018). Response to CT influenced the rate of late obstruction (0% in disease control, 35.7% in disease progression, p = 0.014). However, late obstruction was not associated with stent properties, such as diameter or type (≤22 mm vs. >22 mm, 13.5% vs. 14.3%, p = 1.00; uncovered stent vs. covered stent, 15.5% vs. 7.1%, p = 0.675) and migration (≤22 mm vs. >22 mm, 16.2% vs. 2.9%, p = 0.108; uncovered stent vs. covered stent, 8.6% vs. 14.3%, p = 0.615) in palliative SEMS. The administration of CT increases the rate of stent migration, and disease control by CT can reduce the risk of obstruction by maintaining the luminal patency of palliative SEMSs.

26 CFR 1.534-2 - Burden of proof as to unreasonable accumulations in cases before the Tax Court.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Corporations Used to Avoid Income Tax on Shareholders § 1.534-2 Burden of proof as to unreasonable accumulations in cases... a Tax Court proceeding with respect to an allegation that all or any part of the earnings and...

Student Strip Searches: The Legal and Ethical Implications of "Safford Unified School District v. Redding" for School Leaders

ERIC Educational Resources Information Center

Torres, Mario S.; Brady, Kevin P.; Stefkovich, Jacqueline A.

2011-01-01

The legal freedom from unreasonable searches and seizures is guaranteed to all adult citizens under the Fourth Amendment of the U.S. Constitution. These same legal protections from unreasonable searches and seizures are not guaranteed to today's k-12 student population. School officials are not subject to the same warrant and probable cause…

Rational versus unreasonable persuasion in doctor-patient communication: a normative account.

PubMed

Rubinelli, Sara

2013-09-01

Persuasion plays a critical role in doctor-patient communication. The relevant literature tends to equate persuasion to manipulation as a suboptimal form of interaction. The objective of this paper is to distinguish among different types of persuasion processes and to highlight when their use can be beneficial or risky from the perspective of the patient's autonomy. This paper presents a conceptual analysis of persuasion based on the analytical and normative frameworks of argumentation theory. Persuasion is a generic term that refers to at least four main forms of persuasion: rational persuasion, unintentional unreasonable persuasion, intentional (without deception) unreasonable persuasion and intentional (with deception) unreasonable persuasion (i.e., manipulation). Rational persuasion can be a process of value for the medical encounter. The other forms of persuasion can negatively impact patients' decision making. They are suboptimal for different reasons that are partly due to the quality of communication, and partly due to ethics of the medical conduct. This paper offers a basis for developing training opportunities that foster deeper understanding of different forms and uses of persuasion. Also, it can inspire the development of educational material for patients targeted to the enhancement of their critical health literacy. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

How Students View the Boundaries Between Their Science and Religious Education Concerning the Origins of Life and the Universe

PubMed Central

BROCK, RICHARD; TABER, KEITH S.; RIGA, FRAN

2016-01-01

ABSTRACT Internationally in secondary schools, lessons are typically taught by subject specialists, raising the question of how to accommodate teaching which bridges the sciences and humanities. This is the first study to look at how students make sense of the teaching they receive in two subjects (science and religious education [RE]) when one subject's curriculum explicitly refers to cross‐disciplinary study and the other does not. Interviews with 61 students in seven schools in England suggested that students perceive a permeable boundary between science and their learning in science lessons and also a permeable boundary between religion and their learning in RE lessons, yet perceive a firm boundary between science lessons and RE lessons. We concluded that it is unreasonable to expect students to transfer instruction about cross‐disciplinary perspectives across such impermeable subject boundaries. Finally, we consider the implications of these findings for the successful management of cross‐disciplinary education. PMID:27812226

How Students View the Boundaries Between Their Science and Religious Education Concerning the Origins of Life and the Universe.

PubMed

Billingsley, Berry; Brock, Richard; Taber, Keith S; Riga, Fran

2016-05-01

Internationally in secondary schools, lessons are typically taught by subject specialists, raising the question of how to accommodate teaching which bridges the sciences and humanities. This is the first study to look at how students make sense of the teaching they receive in two subjects (science and religious education [RE]) when one subject's curriculum explicitly refers to cross-disciplinary study and the other does not. Interviews with 61 students in seven schools in England suggested that students perceive a permeable boundary between science and their learning in science lessons and also a permeable boundary between religion and their learning in RE lessons, yet perceive a firm boundary between science lessons and RE lessons. We concluded that it is unreasonable to expect students to transfer instruction about cross-disciplinary perspectives across such impermeable subject boundaries. Finally, we consider the implications of these findings for the successful management of cross-disciplinary education.

Audit of Mound Plant`s reduction in force

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-05-17

Objective of this audit was to determine whether the Mound Plant`s Fiscal Year 1992 reduction in force (RIF) was effectively managed and implemented properly by DOE. DOE established policy to encourage contractors to reduce staffing by voluntary separations without unreasonable separation costs. EG&G Mound`s FY 1992 RIF was accomplished by voluntary separations; however, its implementation unreasonably increased costs because DOE did not have adequate criteria or guidelines for evaluating contractors` RIF proposals, and because EG&G Mound furnished inaccurate cost data to DOE evaluators. The unreasonable costs amounted to at least $21 million. Recommendations are made that DOE develop and implementmore » guidelines to impose limitations on voluntary separation allowances, early retirement incentive payments, and inclusion of crucial employee classifications in voluntary RIFs.« less

Efficacy of loop colostomy construction for acute left-sided colonic obstructions: a cohort analysis.

PubMed

Amelung, Femke J; Mulder, Charlotte L J; Broeders, Ivo A M J; Consten, Esther C J; Draaisma, Werner A

2017-03-01

Acute primary resection as treatment for left-sided colonic obstruction (LSCO) is notorious for its high morbidity and mortality rates. Both stenting and loop colostomy construction can serve as a bridge to surgery, hereby avoiding the high morbidity and mortality rates associated with emergency resections. This study aims to investigate the safety of a loop colostomy in patients presenting with acute LSCO. Retrospective analysis of all patients that received a loop colostomy for LSCO between 2003 and 2015 was performed. Primary outcomes were mortality, major morbidity (Clavien-Dindo grades III-IV) and minor morbidity (Clavien-Dindo grades I-II). One hundred forty-six patients presenting with acute LSCO received a diverting colostomy. After colostomy construction, mortality occurred in four patients (2.7%) and major complications were reported in 20 patients (13.7%). In 61 patients, the diverting colostomy served as a palliative measure, because of metastatic disease or unfitness for major surgery. The remaining 85 patients all underwent delayed resection, resulting in an overall mortality, major morbidity and minor morbidity of 6.9% (n = 6), 14.0% (n = 12) and 26.7% (n = 23), respectively. Diverting colostomy construction is a minimally invasive and safe treatment option for LSCO. It can serve as a definite palliative measure, as well as a bridge to elective surgery. A diverting colostomy as a bridge to surgery might even be a valid alternative for emergency resections, since mortality and morbidity rates following colostomy construction and delayed resection appear lower than reported outcomes following primary resection.

Self-expanding metallic stents drainage for acute proximal colon obstruction

PubMed Central

Yao, Li-Qin; Zhong, Yun-Shi; Xu, Mei-Dong; Xu, Jian-Min; Zhou, Ping-Hong; Cai, Xian-Li

2011-01-01

AIM: To clarify the usefulness of the self-expanding metallic stents (SEMS) in the management of acute proximal colon obstruction due to colon carcinoma before curative surgery. METHODS: Eighty-one colon (proximal to spleen flex) carcinoma patients (47 males and 34 females, aged 18-94 years, mean = 66.2 years) treated between September 2004 and June 2010 for acute colon obstruction were enrolled to this study, and their clinical and radiological features were reviewed. After a cleaning enema was administered, urgent colonoscopy was performed. Subsequently, endoscopic decompression using SEMS placement was attempted. RESULTS: Endoscopic decompression using SEMS placement was technically successful in 78 (96.3%) of 81 patients. Three patients’ symptoms could not be relieved after SEMS placement and emergent operation was performed 1 d later. The site of obstruction was transverse colon in 18 patients, the hepatic flex in 42, and the ascending colon in 21. Following adequate cleansing of the colon, patients’ abdominal girth was decreased from 88 ± 3 cm before drainage to 72 ± 6 cm 7 d later, and one-stage surgery after 8 ± 1 d (range, 7-10 d) was performed. No anastomotic leakage or postoperative stenosis occurred after operation. CONCLUSION: SEMS placement is effective and safe in the management of acute proximal colon obstruction due to colon carcinoma, and is considered as a bridged method before curative surgery. PMID:21876623

75 FR 81003 - Rate Increase Disclosure and Review

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-23

...This document contains proposed regulations implementing the rules for health insurance issuers regarding the disclosure and review of unreasonable premium increases under section 2794 of the Public Health Service Act. The proposed rule would establish a rate review program to ensure that all rate increases that meet or exceed an established threshold are reviewed by a State or HHS to determine whether the rate increases are unreasonable.

Artiss Symposium 2013: Psychiatry and Sleep Disorders

DTIC Science & Technology

2013-06-05

disorder have insomnia and 50 to 80% of patients with post-traumatic stress disorder also have obstructive sleep apnea. How can we manage these patients in...osteoarthritis, and coronary artery dis- ease relative to a relaxation/ stress management /wellness control group. In all three chronic medical conditions, CBT...of Traumatic Stress ; Dept. of Psychiatry, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814 8

Aligned nanofibrillar collagen scaffolds - Guiding lymphangiogenesis for treatment of acquired lymphedema.

PubMed

Hadamitzky, Catarina; Zaitseva, Tatiana S; Bazalova-Carter, Magdalena; Paukshto, Michael V; Hou, Luqia; Strassberg, Zachary; Ferguson, James; Matsuura, Yuka; Dash, Rajesh; Yang, Phillip C; Kretchetov, Shura; Vogt, Peter M; Rockson, Stanley G; Cooke, John P; Huang, Ngan F

2016-09-01

Secondary lymphedema is a common disorder associated with acquired functional impairment of the lymphatic system. The goal of this study was to evaluate the therapeutic efficacy of aligned nanofibrillar collagen scaffolds (BioBridge) positioned across the area of lymphatic obstruction in guiding lymphatic regeneration. In a porcine model of acquired lymphedema, animals were treated with BioBridge scaffolds, alone or in conjunction with autologous lymph node transfer as a source of endogenous lymphatic growth factor. They were compared with a surgical control group and a second control group in which the implanted BioBridge was supplemented with exogenous vascular endothelial growth factor-C (VEGF-C). Three months after implantation, immunofluorescence staining of lymphatic vessels demonstrated a significant increase in lymphatic collectors within close proximity to the scaffolds. To quantify the functional impact of scaffold implantation, bioimpedance was used as an early indicator of extracellular fluid accumulation. In comparison to the levels prior to implantation, the bioimpedance ratio was significantly improved only in the experimental BioBridge recipients with or without lymph node transfer, suggesting restoration of functional lymphatic drainage. These results further correlated with quantifiable lymphatic collectors, as visualized by contrast-enhanced computed tomography. They demonstrate the therapeutic potential of BioBridge scaffolds in secondary lymphedema. Copyright © 2016 Elsevier Ltd. All rights reserved.

CTC Sentinel. Volume 9, Issue 10, October 2016

DTIC Science & Technology

2016-10-01

attacking bridges with car bombs in order to obstruct security force reinforcement of the area; use of platoon-sized assaults to overrun police...complexes, bomb -making factories, supply points, and training camps.j In Au- gust 2015 insurgents extended their presence into the DRV groves south of...intent in his February 2004 letter to Ayman al-Zawahiri.33 The Islamic State has already begun to bait Badr and the PMF with local car bombings

The Rise of Islam in Turkey: Opportunity or Obstruction for the West?

DTIC Science & Technology

2011-06-17

religious hijab , or headscarf, to be worn in public buildings and second, they elected Abdullah Gul, whose wife wears a headscarf, as president of...ABSTRACT As a predominantly Muslim nation with a democratic tradition and government, Turkey has become the figurative bridge between the democratic...West and the Islamic East. Within the past decade, Turkey has embraced its unique position and now seeks to become a major player in the international

Iliocaval Confluence Stenting for Chronic Venous Obstructions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Graaf, Rick de, E-mail: r.de.graaf@mumc.nl; Wolf, Mark de, E-mail: markthewolf@gmail.com; Sailer, Anna M., E-mail: anni.sailer@mumc.nl

PurposeDifferent techniques have been described for stenting of venous obstructions. We report our experience with two different confluence stenting techniques to treat chronic bi-iliocaval obstructions.Materials and MethodsBetween 11/2009 and 08/2014 we treated 40 patients for chronic total bi-iliocaval obstructions. Pre-operative magnetic resonance venography showed bilateral extensive post-thrombotic scarring in common and external iliac veins as well as obstruction of the inferior vena cava (IVC). Stenting of the IVC was performed with large self-expandable stents down to the level of the iliocaval confluence. To bridge the confluence, either self-expandable stents were placed inside the IVC stent (24 patients, SECS group) ormore » high radial force balloon-expandable stents were placed at the same level (16 patients, BECS group). In both cases, bilateral iliac extensions were performed using nitinol stents.ResultsRecanalization was achieved for all patients. In 15 (38 %) patients, a hybrid procedure with endophlebectomy and arteriovenous fistula creation needed to be performed because of significant involvement of inflow vessels below the inguinal ligament. Mean follow-up was 443 ± 438 days (range 7–1683 days). For all patients, primary, assisted-primary, and secondary patency rate at 36 months were 70, 73, and 78 %, respectively. Twelve-month patency rates in the SECS group were 85, 85, and 95 % for primary, assisted-primary, and secondary patency. In the BECS group, primary patency was 100 % during a mean follow-up period of 134 ± 118 (range 29–337) days.ConclusionStenting of chronic bi-iliocaval obstruction shows relatively high patency rates at medium follow-up. Short-term patency seems to favor confluence stenting with balloon-expandable stents.« less

Launch Risk Acceptability: The Public Speaks

NASA Technical Reports Server (NTRS)

Haber, Jerold M.; Lamoreaux, Richard W.

2008-01-01

The perspective of those assuming risk has become increasingly important to launch agencies. The IAASS white paper "An ICAO for Space?" proposed four ultimate goals of any international regulatory framework. The first of these was to "Ensure that citizens of all nations are equally protected from "unreasonable levels" of risk from overflight by missiles, launch vehicles and returning spacecraft". A key component of this concept is the issue of what is an "unreasonable level" of risk from the perspective of those assuming the risk.

Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need

PubMed Central

Corcoran, David

2018-01-01

The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation. This clinical paradigm fails to account for the considerable proportion (approximately one-third) of patients with angina in whom obstructive CAD is excluded. This common scenario presents a diagnostic conundrum whereby angina occurs but there is no obstructive CAD (ischaemia and no obstructive coronary artery disease—INOCA). We review new insights into the pathophysiology of angina whereby myocardial ischaemia results from a deficient supply of oxygenated blood to the myocardium, due to various combinations of focal or diffuse epicardial disease (macrovascular), microvascular dysfunction or both. Macrovascular disease may be due to the presence of obstructive CAD secondary to atherosclerosis, or may be dynamic due to a functional disorder (eg, coronary artery spasm, myocardial bridging). Pathophysiology of coronary microvascular disease may involve anatomical abnormalities resulting in increased coronary resistance, or functional abnormalities resulting in abnormal vasomotor tone. We consider novel clinical diagnostic techniques enabling new insights into the causes of angina and appraise the need for improved therapeutic options for patients with INOCA. We conclude that the taxonomy of stable CAD could improve to better reflect the heterogeneous pathophysiology of the coronary circulation. We propose the term ‘stable coronary syndromes’ (SCS), which aligns with the well-established terminology for ‘acute coronary syndromes’. SCS subtends a clinically relevant classification that more fully encompasses the different diseases of the epicardial and microvascular coronary circulation. PMID:29030424

Emergency Management of Malignant Acute Left-Sided Colonic Obstruction

PubMed Central

Trompetas, Vasileios

2008-01-01

INTRODUCTION The management of acute left-sided colonic obstruction still remains a challenging problem despite significant progress. METHODS A literature search was undertaken using PubMed and the Cochrane Library regarding the options in emergency management of left-sided colonic obstruction focusing on outcomes such as mortality, morbidity, long-term prognosis and cost effectiveness. DISCUSSION Colonic stenting is the best option either for palliation or as a bridge to surgery. It reduces morbidity and mortality rate and the need for colostomy formation. Stenting is likely to be cost effective, but data are variable depending on the individual healthcare system. Nevertheless, surgical management remains relevant as colonic stenting has a small rate of failure, and it is not always available. There are various surgical options. One-stage primary resection and anastomosis is the preferred choice for low-risk patients. Intra-operative colonic irrigation has no proven benefit. Subtotal colectomy is useful in cases of proximal bowel damage or synchronous tumours. Hartmann's procedure should be reserved for high-risk patients. Simple colostomy has no role other than for use in very ill patients who are not fit for any other procedure. PMID:18430330

Theoretical Explanations in Mathematical Physics

NASA Astrophysics Data System (ADS)

Rivadulla, Andrés

Many physicists wonder at the usefulness of mathematics in physics. According Madrid to Einstein mathematics is admirably appropriate to the objects of reality. Wigner asserts that mathematics plays an unreasonable important role in physics. James Jeans affirms that God is a mathematician, and that the first aim of physics is to discover the laws of nature, which are written in mathematical language. Dirac suggests that God may have used very advanced mathematics in constructing the universe. And Barrow adheres himself to Wigner's claim about the unreasonable effectiveness of mathematics for the workings of the physical world.

Self-expandable metallic stent as a bridge to elective surgery versus emergency surgery for acute malignant colorectal obstruction.

PubMed

Li, Zhi-Xiong; Wu, Xiao-Hua; Wu, Hai-yan; Chang, Wen-Ju; Chang, Xiu-juan; Yi, Tuo; Shi, Qiang; Chen, Jing-Wen; Feng, Qing-Yang; Zhu, De-Xiang; Wei, Ye; Zhong, Yun-Shi; Xu, Jian-Min

2016-03-01

The efficacy and safety of self-expandable metallic stents (SEMSs) as a bridge for patients with acute malignant colorectal obstructions (AMCOs) are still controversial. We conducted this study to evaluate the outcomes of patients with AMCOs treated by different strategies. From January 2010 to March 2014, a total of 171 patients with AMCOs from Zhongshan Hospital were retrospectively enrolled in this study. One hundred twenty patients successfully received stent placement followed by one-stage laparoscopic or open resection in the stent group, and 51 patients received emergency operations in the emergency group. The operation duration and postoperative hospital stay were significantly shorter in the stent group (114.51 ± 28.65 vs. 160.39 ± 58.94 min, P < 0.001; 8.00 ± 3.97 vs. 12.59 ± 9.07 days, P = 0.001). The stent group also had significantly reduced intraoperative blood loss and the incidence of postoperative complications compared with the emergency group (61.00 ± 43.70 vs. 121.18 ± 85.90 ml, P < 0.001; 16.7 vs. 37.3%, P = 0.003). Kaplan-Meier survival curves showed that the median survival time in the stent group was significantly longer than that in the emergency group (53 vs. 41 months, P = 0.034). In subgroup analysis of stent group, the stent laparoscopy group had significantly decreased postoperative complications (P = 0.025), and similar long-term survival (P = 0.81). Stent placement as a bridge to surgery is a safe and feasible procedure and provides significant advantages in terms of short-term outcomes and favorable prognoses for patients with AMCOs. Laparoscopic surgery could be considered as an optimal treatment after stent placement.

Self-expandable metal stents for relieving malignant colorectal obstruction: short-term safety and efficacy within 30 days of stent procedure in 447 patients.

PubMed

Meisner, Søren; González-Huix, Ferran; Vandervoort, Jo G; Goldberg, Paul; Casellas, Juan A; Roncero, Oscar; Grund, Karl E; Alvarez, Alberto; García-Cano, Jesús; Vázquez-Astray, Enrique; Jiménez-Pérez, Javier

2011-10-01

The self-expandable metal stent (SEMS) can alleviate malignant colonic obstruction and avoid emergency decompressive surgery. To document performance, safety, and effectiveness of colorectal stents used per local standards of practice in patients with malignant large-bowel obstruction to avoid palliative stoma surgery in incurable patients (PAL) and facilitate bowel decompression as a bridge to surgery for curable patients (BTS). Prospective clinical cohort study. Two global registries with 39 academic and community centers. This study involved 447 patients with malignant colonic obstruction who received stents (255 PAL, 182 BTS, 10 no indication specified). Colorectal through-the-scope SEMS placement. The primary endpoint was clinical success at 30 days, defined as the patient's ability to maintain bowel function without adverse events related to the procedure or stent. Secondary endpoints were procedural success, defined as successful stent placement in the correct position, symptoms of persistent or recurrent colonic obstruction, and complications. The procedural success rate was 94.8% (439/463), and the clinical success rates were 90.5% (313/346) as assessed on a per protocol basis and 71.6% (313/437) as assessed on an intent-to-treat basis. Complications included 15 (3.9%) perforations, 3 resulting in death, 7 (1.8%) migrations, 7 (1.8%) cases of pain, and 2 (0.5%) cases of bleeding. No control group. No primary endpoint analysis data for 25% of patients. This largest multicenter, prospective study of colonic SEMS placement demonstrates that colonic SEMSs are safe and highly effective for the short-term treatment of malignant colorectal obstruction, allowing most curable patients to have 1-step resection without stoma and providing most incurable patients minimally invasive palliation instead of surgery. The risk of complications, including perforation, was low. Copyright © 2011 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

Tracking Pulse Oximeter Findings Before, During and After Titration of Mandibular Advancement Devices (MAD) for Patients With Mild to Moderate Obstructive Sleep Apnea (OSA)

DTIC Science & Technology

2015-06-01

CP AP because of claustrophobia, noise, nose bleeds, dermatitis and nasal bridge sores. In many cases, these effects are due to incorrect pressure...checked for contact data in case a subject must be contacted due to scheduling problems, or some new information is learned that a subject needs to know...Subject initiated contacts via phone or email to the PI with respect to adverse events, side effects or questions will be recorded on an electronic log

Streambed stresses and flow around bridge piers

USGS Publications Warehouse

Parola, A.C.; Ruhl, K.J.; Hagerty, D.J.; Brown, B.M.; Ford, D.L.; Korves, A.A.

1996-01-01

Scour of streambed material around bridge foundations by floodwaters is the leading cause of catastrophic bridge failure in the United States. The potential for scour and the stability of riprap used to protect the streambed from scour during extreme flood events must be known to evaluate the likelihood of bridge failure. A parameter used in estimating the potential for scour and removal of riprap protection is the time-averaged shear stress on the streambed often referred to as boundary stress. Bridge components, such as bridge piers and abutments, obstruct flow and induce strong vortex systems that create streambed or boundary stresses significantly higher than those in unobstructed flow. These locally high stresses can erode the streambed around pier and abutment foundations to the extent that the foundation is undermined, resulting in settlement or collapse of bridge spans. The purpose of this study was to estimate streambed stresses at a bridge pier under full-scale flow conditions and to compare these stresses with those obtained previously in small-scale model studies. Two-dimensional velocity data were collected for three flow conditions around a bridge pier at the Kentucky State Highway 417 bridge over the Green River at Greensburg in Green County, Ky. Velocity vector plots and the horizontal component of streambed stress contour plots were developed from the velocity data. The streambed stress contours were developed using both a near-bed velocity and velocity gradient method. Maximum near-bed velocities measured at the pier for the three flow conditions were 1.5, 1.6, and 2.0 times the average near-bed velocities measured in the upstream approach flow. Maximum streambed stresses for the three flow conditions were determined to be 10, 15, and 36 times the streambed stresses of the upstream approach flow. Both the near-bed velocity measurements and approximate maximum streambed stresses at the full-scale pier were consistent with those observed in experiments using small-scale models in which similar data were collected, except for a single observation of the near-bed velocity data and the corresponding streambed stress determination. The location of the maximum streambed stress was immediately downstream of a 90 degree radial of the upstream cylinder (with the center of the upstream cylinder being the origin) for the three flow conditions. This location was close to the flow wake separation point at the upstream cylinder. Other researchers have observed the maximum streambed stress around circular cylinders at this location or at a location immediately upstream of the wake separation point. Although the magnitudes of the estimated streambed stresses measured at the full-scale pier were consistent with those measured in small-scale model studies, the stress distributions were significantly different than those measured in small-scale models. The most significant discrepancies between stress contours developed in this study and those developed in the small-scale studies for flow around cylindrical piers on a flat streambed were associated with the shape of the stress contours. The extent of the high stress region of the streambed around the full-scale pier was substantially larger than the diameter of the upstream cylinder, while small-scale models had small regions compared to the diameter of the model cylinders. In addition, considerable asymmetry in the stress contours was observed. The large region of high stress and asymmetry was attributed to several factors including (1) the geometry of the full-scale pier, (2) the non-planar topography of the streambed, (3) the 20 degree skew of the pier to the approaching flow, and (4) the non-uniformity of the approach flow. The extent of effect of the pier on streambed stresses was found to be larger for the full-scale site than for model studies. The results from the model studies indicated that the streambed stresses created by the obstruction of flow by the 3-foot wide pi

The road to sustainability must bridge three great divides.

PubMed

Aronson, James; Blignaut, James N; de Groot, Rudolf S; Clewell, Andre; Lowry, Porter P; Woodworth, Paddy; Cowling, Richard M; Renison, Daniel; Farley, Joshua; Fontaine, Christelle; Tongway, David; Levy, Samuel; Milton, Suzanne J; Rangel, Orlando; Debrincat, Bev; Birkinshaw, Chris

2010-01-01

The world's large and rapidly growing human population is exhausting Earth's natural capital at ever-faster rates, and yet appears mostly oblivious to the fact that these resources are limited. This is dangerous for our well-being and perhaps for our survival, as documented by numerous studies over many years. Why are we not moving instead toward sustainable levels of use? We argue here that this disconnection between our knowledge and our actions is largely caused by three "great divides": an ideological divide between economists and ecologists; an economic development divide between the rich and the poor; and an information divide, which obstructs communications between scientists, public opinion, and policy makers. These divides prevent our economies from responding effectively to urgent signals of environmental and ecological stress. The restoration of natural capital (RNC) can be an important strategy in bridging all of these divides. RNC projects and programs make explicit the multiple and mutually reinforcing linkages between environmental and economic well-being, while opening up a promising policy road in the search for a sustainable and desirable future for global society. The bridge-building capacity of RNC derives from its double focus: on the ecological restoration of degraded, overexploited natural ecosystems, and on the full socio-economic and ecological interface between people and their environments.

Reduced channel conveyance on the Wichita River at Wichita Falls, Texas, 1900-2009

USGS Publications Warehouse

Winters, Karl; Baldys, Stanley; Schreiber, Russell

2010-01-01

Recent floods on the Wichita River at Wichita Falls, Texas, have reached higher stages compared to historical floods of similar magnitude discharges. The U.S. Geological Survey (USGS) has operated streamflow-gaging station 07312500 Wichita River at Wichita Falls, Tex., since 1938 and flood measurements near the location of the present gage were first made in 1900. Floods recorded in 2007 and 2008 at this gaging station, including the record flood of June 30, 2007, reached higher stages compared to historical floods before 1972 of similar peak discharges. For flood measurements made at stages of more than 18 feet, peak stages were about 1 to 3 feet higher compared to peak stages of similar peak discharges measured before 1972. Flood measurements made at stages of more than 18 feet also indicate a decrease in the measured mean velocity from about 3.5 to about 2.0 feet per second from 1941 to 2008. The increase in stage and decrease in streamflow velocity for similar magnitude floods indicates channel conveyance has decreased over time. A study to investigate the causes of reduced channel conveyance in the Wichita River reach from Loop 11 downstream to River Road in Wichita Falls was done by the USGS in cooperation with the City of Wichita Falls. Historical photographs indicate substantial growth of riparian vegetation downstream from Loop 11 between 1950 and 2009. Aerial photographs taken between 1950 and 2008 also indicate an increase in riparian vegetation. Twenty-five channel cross sections were surveyed by the USGS in this reach in 2009. These cross sections were located at bridge crossings or collocated with channel cross sections previously surveyed in 1986 for use in a floodplain mapping study by the Federal Emergency Management Agency. Four channel cross sections 3,400 to 11,900 feet downstream from Martin Luther King Jr. Boulevard indicate narrowing of the channel. The remaining channel cross sections surveyed in 2009 by the USGS compared favorably with cross sections surveyed in 1986 for the Federal Emergency Management Agency, with no substantial differences noted. Comparison of channel cross sections surveyed in 2009 to those from historic bridge plans indicate no change in cross section has occurred at most of the bridges from Loop 11 downstream to River Road in Wichita Falls, except for obstructions noted at the Scott Avenue bridge and Martin Luther King Jr. bridge. Although obstructions in the channel at these bridges only partially block flow, they could also be contributing to reduced channel conveyance. Step-backwater profiles were used by the USGS to verify channel roughness. The main channel roughness coefficients (Manning's n values) from 2009 surveys were virtually unchanged from those used in a 1991 hydraulic model done for the Federal Emergency Management Agency. The average overbank roughness coefficient (Manning's n value) was 0.15, more than double the value of 0.06 used in the 1991 hydraulic model. Increased overbank vegetation has resulted in higher stages conveying the same amount of discharge, particularly for discharges more than 4,000 cubic feet per second.

Colonic stenting as a bridge to surgery for obstructive colorectal cancer: advantages and disadvantages.

PubMed

Haraguchi, Naotsugu; Ikeda, Masataka; Miyake, Masakazu; Yamada, Takuya; Sakakibara, Yuko; Mita, Eiji; Doki, Yuichiro; Mori, Masaki; Sekimoto, Mitsugu

2016-11-01

To clarify the advantages and disadvantages of stenting as a bridge to surgery (BTS) by comparing the clinical features and outcomes of patients who underwent BTS with those of patients who underwent emergency surgery (ES). We assessed technical success, clinical success, surgical procedures, stoma formation, complications, clinicopathological features, and Onodera's prognostic nutritional index (OPNI) in patients who underwent BTS and those who underwent ES. Twenty-six patients underwent stenting, which was successful in 22 (BTS group). The remaining four patients with unsuccessful stenting underwent emergency surgery. A total of 22 patients underwent emergency surgery (ES group). The rates of technical and clinical success were 85.0 and 81.0 %, respectively. The proportion of patients able to be treated by laparoscopic surgery (P = 0.0001) and avoid colostomy (P = 0.0042) was significantly higher in the BTS group. Although the incidence of anastomotic leakage in the two groups was not significantly different, it was significantly reduced by colonoscopic evaluation of obstructive colitis (P = 0.0251). The mean number of harvested lymph nodes (P = 0.0056) and the proportion of D3 lymphadenectomy (P = 0.0241) were significantly greater in the BTS group. Perineural invasion (PNI) was noted in 59.1 and 18.2 % of the BTS group and ES group patients, respectively (P = 0.0053). OPNI and serum albumin decreased significantly after stenting (P = 0.0084). The advantages of stenting as a BTS were that it avoided colostomy and allowed for laparoscopic surgery and lymphadenectomy, whereas its disadvantage lay in the decreased PNI and OPNI levels. A larger study including an analysis of prognosis is warranted.

The reasonable effectiveness of mathematics in the natural sciences

NASA Astrophysics Data System (ADS)

Harvey, Alex

2011-12-01

Mathematics and its relation to the physical universe have been the topic of speculation since the days of Pythagoras. Several different views of the nature of mathematics have been considered: Realism—mathematics exists and is discovered; Logicism—all mathematics may be deduced through pure logic; Formalism—mathematics is just the manipulation of formulas and rules invented for the purpose; Intuitionism—mathematics comprises mental constructs governed by self evident rules. The debate among the several schools has major importance in understanding what Eugene Wigner called, The Unreasonable Effectiveness of Mathematics in the Natural Sciences. In return, this `Unreasonable Effectiveness' suggests a possible resolution of the debate in favor of Realism. The crucial element is the extraordinary predictive capacity of mathematical structures descriptive of physical theories.

The Problem of Heroin

ERIC Educational Resources Information Center

Wilson, James Q.; And Others

1972-01-01

Argues that most of the underlying assumptions of presently recommended solutions to the problem of heroin addiction are unreasonable, unwarranted, or at least open to more than one interpretation. (DM)

18 CFR 1300.105 - National origin harassment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... intimidating, hostile, or offensive working environment; (b) Has the purpose or effect of unreasonably interfering with an individual's work performance; or (c) Otherwise adversely affects an individual's...

Orofacial manifestations of achondroplasia

PubMed Central

Rohilla, Smriti; Kaushik, Atul; Vinod, V.C.; Tanwar, Renu; Kumar, Munish

2012-01-01

Achondroplasia (Online Mendelian Inheritance in Man [OMIM] 100800), is considered as a form of skeletal dysplasia dwarfism that manifests with stunted stature and disproportionate limb shortening. Achondroplasia is of special interest in the field of dentistry because of its characteristic craniofacial features which include relative macrocephaly, depressed nasal bridge and maxillary hypoplasia. Presence of large head, implanted shunt, airway obstruction and difficulty in head control requires special precautions during dental management. The current case report highlights the orofacial manifestations of Achondroplasia in a young pediatric patient, along with the multidisciplinary treatment (including the dental treatment) done for the patient which also might help the general practitioners in better understanding of the condition. PMID:27298609

Malathion

EPA Pesticide Factsheets

This organophosphate (OP) insecticide is used in agriculture, residential gardens, public recreation areas, and public health pest control programs. Applied according to label specifications, it can be used to kill mosquitoes without unreasonable risks.

40 CFR 35.710 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... operate compliance monitoring programs to prevent or eliminate unreasonable risks to health or the... Administrator is unable or not likely to take action for their prevention or elimination. (c) Associated program...

48 CFR 1632.770 - Contingency reserve payments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FINANCING Contract Funding 1632.770 Contingency reserve payments. (a) Payments from the contingency reserve... advise the carrier of its decision. However, OPM shall not unreasonably withhold approval for amounts...

Prevention of Unreasonable Fees Act

THOMAS, 112th Congress

Rep. Richardson, Laura [D-CA-37

2011-05-03

House - 05/04/2011 Referred to the Subcommittee on Railroads, Pipelines, and Hazardous Materials. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Principles of Need and the Aggregation Thesis.

PubMed

Gustavsson, Erik; Juth, Niklas

2017-09-02

Principles of need are constantly referred to in health care priority setting. The common denominator for any principle of need is that it will ascribe some kind of special normative weight to people being worse off. However, this common ground does not answer the question how a plausible principle of need should relate to the aggregation of benefits across individuals. Principles of need are sometimes stated as being incompatible with aggregation and sometimes characterized as accepting aggregation in much the same way as utilitarians do. In this paper we argue that if one wants to take principles of need seriously both of these positions have unreasonable implications. We then characterize and defend a principle of need consisting of sufficientarian elements as well as prioritarian which avoids these unreasonable implications.

40 CFR 35.310 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... establish and operate compliance monitoring programs to prevent or eliminate unreasonable risks to health or... which the Administrator is unable or not likely to take action for their prevention or elimination. (c...

25 CFR 700.53 - Dwelling, replacement.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Policies and Instructions Definitions § 700.53 Dwelling, replacement. The term replacement dwelling means a... unreasonable adverse environmental conditions from either natural or man-made sources and in an area not...

Why We Review Pesticides

EPA Pesticide Factsheets

As required by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), EPA periodically reviews existing registered pesticides to ensure they can be used safely, without unreasonable risks to human health and the environment.

33 CFR 334.3 - Special policies.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Food fishing industry. The authority to prescribe danger zone and restricted area regulations must be exercised so as not to unreasonably interfere with or restrict the food fishing industry. Whenever the...

Scientific Misconduct.

ERIC Educational Resources Information Center

Goodstein, David

2002-01-01

Explores scientific fraud, asserting that while few scientists actually falsify results, the field has become so competitive that many are misbehaving in other ways; an example would be unreasonable criticism by anonymous peer reviewers. (EV)

48 CFR 2825.203 - Evaluating offers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... designee at a level not lower than the BPC, is the agency official authorized to make determination that using a particular domestic construction material would unreasonably increase the cost of the...

7 CFR 1486.404 - What expenditures are not eligible for program funding?

Code of Federal Regulations, 2010 CFR

2010-01-01

...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS EMERGING..., unreasonable expenditures, or any cost of: (1) Branded product promotions—in-store, restaurant advertising...

36 CFR 1002.34 - Disorderly conduct.

Code of Federal Regulations, 2011 CFR

2011-07-01

... public alarm, nuisance, jeopardy or violence, or knowingly or recklessly creating a risk thereof, such... incite an immediate breach of the peace. (3) Makes noise that is unreasonable, considering the nature and...

36 CFR 1002.34 - Disorderly conduct.

Code of Federal Regulations, 2010 CFR

2010-07-01

... public alarm, nuisance, jeopardy or violence, or knowingly or recklessly creating a risk thereof, such... incite an immediate breach of the peace. (3) Makes noise that is unreasonable, considering the nature and...

32 CFR 234.7 - Disorderly conduct.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., with intent to cause public alarm, nuisance, jeopardy, or violence, or knowingly or recklessly creating... injury or incite an immediate breach of the peace. (c) Makes noise that is unreasonable, considering the...

32 CFR 234.7 - Disorderly conduct.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., with intent to cause public alarm, nuisance, jeopardy, or violence, or knowingly or recklessly creating... injury or incite an immediate breach of the peace. (c) Makes noise that is unreasonable, considering the...

4 Tips: Asthma and Complementary Health Practices

MedlinePlus

... 2004, the FDA banned the U.S. sale of dietary supplements containing ephedra. The FDA found that these supplements had an unreasonable risk of injury or illness—particularly cardiovascular complications—and ...

Prevention of Unreasonable Fees Act

THOMAS, 111th Congress

Sen. Lautenberg, Frank R. [D-NJ

2009-10-08

Senate - 10/08/2009 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Prevention of Unreasonable Fees Act

THOMAS, 112th Congress

Sen. Lautenberg, Frank R. [D-NJ

2011-11-29

Senate - 11/29/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

36 CFR 2.34 - Disorderly conduct.

Code of Federal Regulations, 2010 CFR

2010-07-01

... conduct when, with intent to cause public alarm, nuisance, jeopardy or violence, or knowingly or... likely to inflict injury or incite an immediate breach of the peace. (3) Makes noise that is unreasonable...

36 CFR 2.34 - Disorderly conduct.

Code of Federal Regulations, 2011 CFR

2011-07-01

... conduct when, with intent to cause public alarm, nuisance, jeopardy or violence, or knowingly or... likely to inflict injury or incite an immediate breach of the peace. (3) Makes noise that is unreasonable...

31 CFR 10.37 - Requirements for other written advice.

Code of Federal Regulations, 2012 CFR

2012-07-01

... assumptions as to future events), unreasonably relies upon representations, statements, findings or agreements... heightened standard of care because of the greater risk caused by the practitioner's lack of knowledge of the...

31 CFR 10.37 - Requirements for other written advice.

Code of Federal Regulations, 2013 CFR

2013-07-01

... assumptions as to future events), unreasonably relies upon representations, statements, findings or agreements... heightened standard of care because of the greater risk caused by the practitioner's lack of knowledge of the...

5 CFR 294.108 - Procedures for obtaining records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... identified by a technique or process that is not unreasonably burdensome or disruptive to OPM operations. (2... includes material published and offered for sale (e.g., by the Superintendent of Documents, Government...

77 FR 13589 - California Independent System Operator Corporation; Notice of Complaint

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-07

... revise the standard for a determination of liability or indemnity from an ordinary negligence standard to a gross negligence standard. The Complainant challenges that the TCA would be unjust, unreasonable...

16 CFR 1302.2 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-01-01

... FLAMMABLE CONTACT ADHESIVES § 1302.2 Purpose. The purpose of this rule is to ban extremely flammable contact adhesives which have been found to present an unreasonable risk of injury to consumers of burns resulting...

School Avoidance: Tips for Concerned Parents

MedlinePlus

... Threats of physical harm (as from a school bully) Actual physical harm Tips for Concerned Parents: As ... the classroom. If a problem like a school bully or an unreasonable teacher is the cause of ...

48 CFR 42.1302 - Suspension of work.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Delay of Work 42.1302 Suspension of work. A suspension of work under a construction or architect... suspension is unreasonable, the contractor may submit a written claim for increases in the cost of...

48 CFR 42.1302 - Suspension of work.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Delay of Work 42.1302 Suspension of work. A suspension of work under a construction or architect... suspension is unreasonable, the contractor may submit a written claim for increases in the cost of...

48 CFR 42.1302 - Suspension of work.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Delay of Work 42.1302 Suspension of work. A suspension of work under a construction or architect... suspension is unreasonable, the contractor may submit a written claim for increases in the cost of...

48 CFR 42.1302 - Suspension of work.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Delay of Work 42.1302 Suspension of work. A suspension of work under a construction or architect... suspension is unreasonable, the contractor may submit a written claim for increases in the cost of...

48 CFR 42.1302 - Suspension of work.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Delay of Work 42.1302 Suspension of work. A suspension of work under a construction or architect... suspension is unreasonable, the contractor may submit a written claim for increases in the cost of...

40 CFR 725.33 - Incomplete submissions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... which the submitter believes show that the microorganism will not present an unreasonable risk of injury... Director, or a designee, may inform the submitter that the running of the review period will resume on the...

Loss of Consciousness During Single Sling Helicopter Hoist Rescue Resulting in a Fatal Fall.

PubMed

Biles, Jessie; Garner, Alan A

2016-09-01

Although harness suspension trauma has been documented since the 1960s, especially in the mountaineering setting, there is little robust medical research into the area. Helicopter hoist rescue shares similar risks and is reserved for those cases that cannot be accessed safely by other routes, where extrication may be hazardous or will take an unreasonable amount of time. The single sling or chest harness used for hoist rescue is a single harness around the upper torso and is easier and quicker to apply than a stretcher. However, the risks of a chest harness need to be balanced against the patient's condition, the environment, aircraft performance, and the urgency of the rescue. We report an adult male falling 80 ft to his death while being hoisted into a rescue helicopter for a likely fractured ankle. A single rescue sling harness technique was used, but the patient became unconscious, slipped out of the harness, and fell. He had significant comorbidities, including cardiomyopathy, obstructive sleep apnea, morbid obesity, and diabetes. A decrease in cardiac output secondary to thoracic compression was the presumed cause for his loss of consciousness and the potential physiological mechanisms and modifying factors are discussed. Further research into harness suspension trauma is required. Stretcher, double point harnesses, or rescue baskets are likely safer methods of hoisting, especially in a medically compromised patient. Biles J, Garner AA. Loss of consciousness during single sling helicopter hoist rescue resulting in a fatal fall. Aerosp Med Hum Perform. 2016; 87(9):821-824.

SINKEX 2014- Determination and Agreement between Navy and EPA

EPA Pesticide Factsheets

EPA determined that the activity authorized under the ocean dumping general permit for the SINKEX program conducted by Navy does not pose an unreasonable risk of injury to human health or the environment.

Protecting Consumers from Unreasonable Credit Rates Act of 2009

THOMAS, 111th Congress

Sen. Durbin, Richard J. [D-IL

2009-02-26

Senate - 02/26/2009 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Protecting Consumers from Unreasonable Credit Rates Act of 2012

THOMAS, 112th Congress

Sen. Durbin, Richard J. [D-IL

2012-07-26

Senate - 07/26/2012 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Protecting Consumers from Unreasonable Credit Rates Act of 2013

THOMAS, 113th Congress

Sen. Durbin, Richard J. [D-IL

2013-04-09

Senate - 04/09/2013 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Complementary and Alternative Medicine

MedlinePlus

... example, the FDA banned the U.S. sale of dietary supplements containing the herb ephedra, which was often used in weight-loss products, citing that they posed an unreasonable risk of injury or illness—particularly cardiovascular complications—and ...

26 CFR 55.6694-2 - Penalties for understatement due to an unreasonable position.

Code of Federal Regulations, 2011 CFR

2011-04-01

... TREASURY (CONTINUED) MISCELLANEOUS EXCISE TAXES (CONTINUED) EXCISE TAX ON REAL ESTATE INVESTMENT TRUSTS AND REGULATED INVESTMENT COMPANIES Procedure and Administration § 55.6694-2 Penalties for understatement due to...

26 CFR 55.6694-2 - Penalties for understatement due to an unreasonable position.

Code of Federal Regulations, 2013 CFR

2013-04-01

... TREASURY (CONTINUED) MISCELLANEOUS EXCISE TAXES (CONTINUED) EXCISE TAX ON REAL ESTATE INVESTMENT TRUSTS AND REGULATED INVESTMENT COMPANIES Procedure and Administration § 55.6694-2 Penalties for understatement due to...

26 CFR 55.6694-2 - Penalties for understatement due to an unreasonable position.

Code of Federal Regulations, 2012 CFR

2012-04-01

... TREASURY (CONTINUED) MISCELLANEOUS EXCISE TAXES (CONTINUED) EXCISE TAX ON REAL ESTATE INVESTMENT TRUSTS AND REGULATED INVESTMENT COMPANIES Procedure and Administration § 55.6694-2 Penalties for understatement due to...

26 CFR 55.6694-2 - Penalties for understatement due to an unreasonable position.

Code of Federal Regulations, 2014 CFR

2014-04-01

... TREASURY (CONTINUED) MISCELLANEOUS EXCISE TAXES (CONTINUED) EXCISE TAX ON REAL ESTATE INVESTMENT TRUSTS AND REGULATED INVESTMENT COMPANIES Procedure and Administration § 55.6694-2 Penalties for understatement due to...

26 CFR 55.6694-2 - Penalties for understatement due to an unreasonable position.

Code of Federal Regulations, 2010 CFR

2010-04-01

... TREASURY (CONTINUED) MISCELLANEOUS EXCISE TAXES (CONTINUED) EXCISE TAX ON REAL ESTATE INVESTMENT TRUSTS AND REGULATED INVESTMENT COMPANIES Procedure and Administration § 55.6694-2 Penalties for understatement due to...

49 CFR Appendix A to Part 26 - Guidance Concerning Good Faith Efforts

Code of Federal Regulations, 2012 CFR

2012-10-01

... might otherwise prefer to perform these work items with its own forces. C. Providing interested DBEs... difference is excessive or unreasonable. E. Not rejecting DBEs as being unqualified without sound reasons...

49 CFR Appendix A to Part 26 - Guidance Concerning Good Faith Efforts

Code of Federal Regulations, 2013 CFR

2013-10-01

... might otherwise prefer to perform these work items with its own forces. C. Providing interested DBEs... difference is excessive or unreasonable. E. Not rejecting DBEs as being unqualified without sound reasons...

49 CFR Appendix A to Part 26 - Guidance Concerning Good Faith Efforts

Code of Federal Regulations, 2014 CFR

2014-10-01

... might otherwise prefer to perform these work items with its own forces. C. Providing interested DBEs... difference is excessive or unreasonable. E. Not rejecting DBEs as being unqualified without sound reasons...

Impact of endoscopic stent insertion on detection of viable circulating tumor cells from obstructive colorectal cancer

PubMed Central

Yamashita, Shinya; Tanemura, Masahiro; Sawada, Genta; Moon, Jeongho; Shimizu, Yosuke; Yamaguchi, Toshiki; Kuwai, Toshio; Urata, Yasuo; Kuraoka, Kazuya; Hatanaka, Nobutaka; Yamashita, Yoshinori; Taniyama, Kiyomi

2018-01-01

The placement of a self-expanding metallic stent (SEMS) in obstructive colorectal cancer (OCRC) is acknowledged to be a safe and effective procedure for the relief of obstruction. However, there is concern that shear forces acting on the tumor during stent expansion may release cancer cells into the circulation, resulting in a poor prognosis. The aim of the present study was to determine whether colonic stent insertion increases viable circulating tumor cells (v-CTCs). A telomerase-specific replication-selective adenovirus-expressing GFP (TelomeScanF35) detection system was used to detect v-CTCs in 8 OCRC patients with a SEMS before and after stent insertion and after surgical resection. In 7 patients, a SEMS was inserted as a bridge to surgery (BTS), and in one patient, a SEMS was inserted for palliation. Surgical resection (R0) was performed in 7 patients. Four patients had no v-CTCs before SEMS placement, two of four measurable patients had an increased number of v-CTCs after SEMS placement (1–3 v-CTCs), and one of two patients with increased v-CTCs developed distant lymphatic metastasis despite curative resection. Four patients had v-CTCs (1–19 cells) before SEMS placement, and two of these four patients had an increase in the number of v-CTCs (20–21 cells) after SEMS placement, while one of the four patients died early with distant metastasis. The present study demonstrated that endoscopic stent insertion for OCRC may result in tumor cell dissemination into the peripheral circulation and may induce distant metastases. PMID:29391884

Impact of endoscopic stent insertion on detection of viable circulating tumor cells from obstructive colorectal cancer.

PubMed

Yamashita, Shinya; Tanemura, Masahiro; Sawada, Genta; Moon, Jeongho; Shimizu, Yosuke; Yamaguchi, Toshiki; Kuwai, Toshio; Urata, Yasuo; Kuraoka, Kazuya; Hatanaka, Nobutaka; Yamashita, Yoshinori; Taniyama, Kiyomi

2018-01-01

The placement of a self-expanding metallic stent (SEMS) in obstructive colorectal cancer (OCRC) is acknowledged to be a safe and effective procedure for the relief of obstruction. However, there is concern that shear forces acting on the tumor during stent expansion may release cancer cells into the circulation, resulting in a poor prognosis. The aim of the present study was to determine whether colonic stent insertion increases viable circulating tumor cells (v-CTCs). A telomerase-specific replication-selective adenovirus-expressing GFP (TelomeScanF35) detection system was used to detect v-CTCs in 8 OCRC patients with a SEMS before and after stent insertion and after surgical resection. In 7 patients, a SEMS was inserted as a bridge to surgery (BTS), and in one patient, a SEMS was inserted for palliation. Surgical resection (R0) was performed in 7 patients. Four patients had no v-CTCs before SEMS placement, two of four measurable patients had an increased number of v-CTCs after SEMS placement (1-3 v-CTCs), and one of two patients with increased v-CTCs developed distant lymphatic metastasis despite curative resection. Four patients had v-CTCs (1-19 cells) before SEMS placement, and two of these four patients had an increase in the number of v-CTCs (20-21 cells) after SEMS placement, while one of the four patients died early with distant metastasis. The present study demonstrated that endoscopic stent insertion for OCRC may result in tumor cell dissemination into the peripheral circulation and may induce distant metastases.

Biennial report on hazardous materials transportation : calendar years 1994-1995

DOT National Transportation Integrated Search

1996-01-01

Hazardous materials (HM) are substances or : materials determined by the U.S. Department of : Transportation (DOT), or otherwise specified : by statute, to have inherent characteristics, : which may pose an unreasonable risk to the : public's health ...

Key Steps in the Special Review Process

EPA Pesticide Factsheets

EPA uses this process when it has reason to believe that the use of a pesticide may result in unreasonable adverse effects on people or the environment. Steps include comprehensive risk and benefit analyses and multiple Position Documents.

Time to Talk: 7 Things to Know about Complementary Health Practices for Weight Loss

MedlinePlus

... 2004, the FDA banned the U.S. sale of dietary supplements containing ephedra. The FDA found that these supplements had an unreasonable risk of injury or illness—particularly cardiovascular complications—and ...

General Information about Mosquitoes

MedlinePlus

... they can use without posing unreasonable risk to human health and the environment. State and local government agencies play a critical role in protecting public health from mosquito-borne ... use of pesticides for mosquito control is appropriate for their area. ...

Alchemy--A History of Early Technology.

ERIC Educational Resources Information Center

Pollard, A. M.

1988-01-01

Reviews the history of alchemy including personalities and methods. Discusses the philosophy associated with various early chemists and alchemists. Attempts to show that it was not unreasonable for ancient alchemists to believe in the possibility of transmutation. (CW)

Arts practices in unreasonable doubt? Reflections on understandings of arts practices in healthcare contexts.

PubMed

Broderick, Sheelagh

2011-09-01

This article suggests that the discourse on arts and health encompass contemporary arts practices as an active and engaged analytical activity. Distinctions between arts therapy and arts practice are made to suggest that clinical evidence-based evaluation, while appropriate for arts therapy, is not appropriate for arts practice and in effect cast them in unreasonable doubt. Themes in current discourse on "arts" and "health" are broadly sketched to provide a context for discussion of arts practices. Approaches to knowledge validation in relation to each domain are discussed. These discourses are applied to the Irish healthcare context, offering a reading of three different art projects; it suggests a multiplicity of analyses beyond causal positive health gains. It is suggested that the social turn in medicine and the social turn in arts practices share some similar pre-occupations that warrant further attention.

Carry on winning: the gamblers' fallacy creates hot hand effects in online gambling.

PubMed

Xu, Juemin; Harvey, Nigel

2014-05-01

People suffering from the hot-hand fallacy unreasonably expect winning streaks to continue whereas those suffering from the gamblers' fallacy unreasonably expect losing streaks to reverse. We took 565,915 sports bets made by 776 online gamblers in 2010 and analyzed all winning and losing streaks up to a maximum length of six. People who won were more likely to win again (apparently because they chose safer odds than before) whereas those who lost were more likely to lose again (apparently because they chose riskier odds than before). However, selection of safer odds after winning and riskier ones after losing indicates that online sports gamblers expected their luck to reverse: they suffered from the gamblers' fallacy. By believing in the gamblers' fallacy, they created their own hot hands. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

Applicability, Indispensability, and Underdetermination: Puzzling Over Wigner's `Unreasonable Effectiveness of Mathematics'

NASA Astrophysics Data System (ADS)

Gelfert, Axel

2014-05-01

In his influential 1960 paper `The Unreasonable Effectiveness of Mathematics in the Natural Sciences', Eugene P. Wigner raises the question of why something that was developed without concern for empirical facts—mathematics—should turn out to be so powerful in explaining facts about the natural world. Recent philosophy of science has developed `Wigner's puzzle' in two different directions: First, in relation to the supposed indispensability of mathematical facts to particular scientific explanations and, secondly, in connection with the idea that aesthetic criteria track theoretical desiderata such as empirical success. An important aspect of Wigner's article has, however, been overlooked in these debates: his worries about the underdetermination of physical theories by mathematical frameworks. The present paper argues that, by restoring this aspect of Wigner's argument to its proper place, Wigner's puzzle may become an instructive case study for the teaching of core issues in the philosophy of science and its history.

[Refusal of care in the intensive care: how makes decision?].

PubMed

Borel, M; Veber, B; Villette-Baron, K; Hariri, S; Dureuil, B; Hervé, C

2009-11-01

Decision-making bringing to an admission or not in intensive care is complex. The aim of this study is to analyze with an ethical point of view the making decision process leading to the refusal and its consequences. It is proposed a setting in prospect through the principles of beneficence, non-maleficience, respect for autonomy, justice, and the Leonetti law. Prospective study in surgical reanimation at the University Hospital of Rouen over 9 months (November 2007-September 2008). Systematic collection for each non-admitted patient of the general characters, the methods of decision making, immediate becoming and within 48 h Constitution of two groups: patients for whom an admission in intensive care could be an unreasonable situation of obstinacy, and patients for whom an admission in reanimation would not be about unreasonable if it occurred. One hundred and fifty situations were analyzed. The potentially unreasonable character of an admission does not involve necessarily a refusal of care in intensive care. The question of the lack of place and equity in the access to the care is real but relative according to the typology of the patients. The research of the respect of the autonomy of the patient is difficult but could be facilitated. The Leonetti law does not appear to be able to be a framework with the situation of refusal of care in intensive care. It is not a question of going towards a systematic admission in intensive care of any patient proposed, but to make sure that so if there is a refusal, it is carried out according to a step ethically acceptable.

Prevention of Bridge Scour with Non-uniform Circular Piers Plane under Steady Flows

NASA Astrophysics Data System (ADS)

Chen, Hsing-Ting; Wang, Chuan-Yi

2017-04-01

River bed scour and deposit variation extremely severe because of most of rivers are steep and rapid flows, and river discharge extremely unstable and highly unsteady during different seasons in Taiwan. In addition to the obstruction of piers foundation, it causes local scour and threatens the safety of bridges. In the past, riprap, wire gabion or wrap pier works were adopted as the protections of piers foundation, but there were no effectual outcomes. The events of break off piers still happen sometimes. For example, typhoon Kalmaegi (2008) and Morakot (2009) caused heavy damages on Ho-Fon bridge in the Da-jia river and Shuang-Yuan bridge in the Kao-Ping river, respectively. Accordingly, to understand the piers scour system and propose an appropriate protection of piers foundation becomes an important topic for this study currently. This research improves the protection works of the existing uniform bridge pier (diameter D) to ensure the safety of the bridge. The non-uniform plane of circular piers (diameter D*) are placed on the top of a bridge pier foundation to reduce the down flow impacting energy and scour by its' surface roughness characteristics. This study utilize hydraulic models to simulate local scour depth and scour depth change with time for non-uniform pier diameter ratio D/D* of 0.3,0.4,0.5,0.6,0.7 and 0.8, and different type pier and initial bed level (Y) relative under the foundation top elevation under steady flows of V/Vc=0.95,0.80 and 0.65. The research results show that the scour depth increases with an increase of flow intensity (V/Vc) under different types of steady flow hydrographs. The scour depth decreases with increase of initial bed level (Y=+0.2D*,0D*and -0.2D*) relative under the foundation top elevation of the different type pier. The maximum scour depth occurred in the front of the pier for all conditions. Because of the scouring retardation by the non-uniform plane of foundation, the scour depth is reduced for the un-exposed bridge foundation (Y=+0.2D*) under any steady flows. Opposite results are found for the exposed (Y=-0.2D*) bridge foundation. For the condition non-uniform pier diameter ratio (D/D*=0.3 0.8) scours, when D/D* is equal to 0.4, because pier oncoming flow area is the smallest one so that down flow intensity is less; as non-uniform area is bigger and decrease more down flow energy so that bring smaller scour depth and effect area. Therefore, local scour depth for pier diameter ratio of 0.4 is less than other type of pier. Considering the safety of bridge structure, a non-uniform circular pier with D/D* which equals to 0.4 and initial bed level relative to Y=+0.2D* is the most ideal pier allocations.

Parents Say the Darndest Things.

ERIC Educational Resources Information Center

Harden, G. Daniel

1993-01-01

A former school principal describes a dozen situations involving parents' excuses for their children's bad behavior or complaints about school procedures and supervisory practices. Suitable administrator responses are given concerning homework completion, "unreasonable" school expectations, divergent interpretations of student attitudes and…

76 FR 53165 - Certification Related to Aerial Eradication in Colombia

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-25

... certify that: (1) The herbicide used for aerial eradication of illicit crops in Colombia is being used in... Colombian laws; (2) the herbicide, in the manner it is being used, does not pose unreasonable risks or...

9 CFR 203.5 - Statement with respect to market agencies paying the expenses of livestock buyers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... sales conducted by such market agencies, such as, expenses for meals, lodging, travel, entertainment and... competition between similarly engaged market agencies and results in undue and unreasonable cost burdens on...

Regulatory Determinations made under Section 5 of the Toxic Substances Control Act (TSCA)

EPA Pesticide Factsheets

In the New Chemicals program, EPA reviews and determines if a chemical contains unreasonable risk both in the context of individual chemical substances and in considering whether to exempt categories of chemical substances.

The use of three-parameter rating table lookup programs, RDRAT and PARM3, in hydraulic flow models

USGS Publications Warehouse

Sanders, C.L.

1995-01-01

Subroutines RDRAT and PARM3 enable computer programs such as the BRANCH open-channel unsteady-flow model to route flows through or over combinations of critical-flow sections, culverts, bridges, road- overflow sections, fixed spillways, and(or) dams. The subroutines also obstruct upstream flow to simulate operation of flapper-type tide gates. A multiplier can be applied by date and time to simulate varying numbers of tide gates being open or alternative construction scenarios for multiple culverts. The subroutines use three-parameter (headwater, tailwater, and discharge) rating table lookup methods. These tables may be manually prepared using other programs that do step-backwater computations or compute flow through bridges and culverts or over dams. The subroutine, therefore, precludes the necessity of incorporating considerable hydraulic computational code into the client program, and provides complete flexibility for users of the model for routing flow through almost any affixed structure or combination of structures. The subroutines are written in Fortran 77 language, and have minimal exchange of information with the BRANCH model or other possible client programs. The report documents the interpolation methodology, data input requirements, and software.

31 CFR 10.37 - Requirements for written advice.

Code of Federal Regulations, 2014 CFR

2014-07-01

...' professional knowledge on Federal tax matters are not considered written advice on a Federal tax matter for... representations, statements, findings, or agreements (including projections, financial forecasts, or appraisals... on representations, statements, findings, or agreements is unreasonable if the practitioner knows or...

16 CFR 1402.2 - Background.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS CB BASE STATION... electrocutions which have occurred when consumers contacted powerlines with CB base station and outside TV... help protect the public against the unreasonable risk of injury associated with CB base station...

49 CFR 381.205 - How do I determine when I may request a waiver?

Code of Federal Regulations, 2014 CFR

2014-10-01

... from using or operating CMVs, or make it unreasonably difficult to do so, during a unique, non... alternatives already available that would allow your use or operation of CMVs during the event. You should also...

49 CFR 381.205 - How do I determine when I may request a waiver?

Code of Federal Regulations, 2011 CFR

2011-10-01

... from using or operating CMVs, or make it unreasonably difficult to do so, during a unique, non... alternatives already available that would allow your use or operation of CMVs during the event. You should also...

49 CFR 381.205 - How do I determine when I may request a waiver?

Code of Federal Regulations, 2012 CFR

2012-10-01

... from using or operating CMVs, or make it unreasonably difficult to do so, during a unique, non... alternatives already available that would allow your use or operation of CMVs during the event. You should also...

49 CFR 381.205 - How do I determine when I may request a waiver?

Code of Federal Regulations, 2010 CFR

2010-10-01

... from using or operating CMVs, or make it unreasonably difficult to do so, during a unique, non... alternatives already available that would allow your use or operation of CMVs during the event. You should also...

49 CFR 381.205 - How do I determine when I may request a waiver?

Code of Federal Regulations, 2013 CFR

2013-10-01

... from using or operating CMVs, or make it unreasonably difficult to do so, during a unique, non... alternatives already available that would allow your use or operation of CMVs during the event. You should also...

Ubertool: Web Application for Ecological Risk Assessment of Pesticides

EPA Science Inventory

Under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) the U.S. Environmental Protection Agency (EPA) must regulate (license) pesticides before they become commercially available to ensure they will not cause unreasonable adverse effects on human health or the envi...

29 CFR 452.54 - Retroactive rules.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS GENERAL STATEMENT CONCERNING THE ELECTION PROVISIONS OF THE LABOR-MANAGEMENT REPORTING AND DISCLOSURE ACT... of the requirement. It would be unreasonable for a labor organization to enforce eligibility...

29 CFR 452.54 - Retroactive rules.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS GENERAL STATEMENT CONCERNING THE ELECTION PROVISIONS OF THE LABOR-MANAGEMENT REPORTING AND DISCLOSURE ACT... of the requirement. It would be unreasonable for a labor organization to enforce eligibility...

Separating Myth from Reality.

ERIC Educational Resources Information Center

Gluckman, Ivan B.

1985-01-01

Civil libertarians and members of more conservative special interest groups have equally legitimate concerns for the educational needs of students attending public schools. The goals and desires of concerned citizens from both sides can be met if neither makes unreasonable demands upon each other. (MD)

Balancing Duties and Rights.

ERIC Educational Resources Information Center

McCarthy, Martha M.; Webb, L. Dean

2000-01-01

Schools are legally obligated to protect students from injury, report child abuse, and curtail harassment and hate crimes. Educators' duties to maintain safe school environments often conflict with students' constitutionally protected rights governing expression, appearance, unreasonable searches, and due process regarding zero-tolerance policies…

40 CFR 125.121 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS... exposure to pollutants or through consumption of exposed aquatic organisms, or (3) Loss of esthetic, recreational, scientific or economic values which is unreasonable in relation to the benefit derived from the...

40 CFR 125.121 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS... exposure to pollutants or through consumption of exposed aquatic organisms, or (3) Loss of esthetic, recreational, scientific or economic values which is unreasonable in relation to the benefit derived from the...

40 CFR 125.121 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS... exposure to pollutants or through consumption of exposed aquatic organisms, or (3) Loss of esthetic, recreational, scientific or economic values which is unreasonable in relation to the benefit derived from the...

40 CFR 125.121 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS... exposure to pollutants or through consumption of exposed aquatic organisms, or (3) Loss of esthetic, recreational, scientific or economic values which is unreasonable in relation to the benefit derived from the...

10 CFR 60.31 - Construction authorization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPOSITORIES Licenses Construction Authorization § 60.31 Construction authorization. Upon review and... in a geologic repository operations area of the design proposed without unreasonable risk to the...: (1) DOE has described the proposed geologic repository including but not limited to: (i) The geologic...

Effects of 6/6 and 4/8 watch systems on sleepiness among bridge officers.

PubMed

Härmä, Mikko; Partinen, Markku; Repo, Risto; Sorsa, Matti; Siivonen, Pertti

2008-04-01

During the last ten years, severe sleepiness or falling asleep by watch keeping officers has been a direct or a contributing factor in a number of maritime accidents. This study examined the relationship between two watch systems and its impact on fatigue and sleepiness in bridge officers. A questionnaire and a sleep/work diary were sent to a representative sample of the Finnish Maritime Officer Association. In all, 185 bridge officers answered the questionnaire on sleep, work hours, and safety, including the Skogby Excessive Daytime Sleepiness index (SEDS); 42% of the bridge officers worked two 4 h watches (4/8) per day, while 26% worked two 6 h watches per day (6/6). Ninety-five of the participants completed a sleep diary for seven consecutive days while at sea. The timing of the watch duties and sleep was recorded, as was subjective sleepiness every 2 h using the Karolinska Sleepiness Scale (KSS). 17.6% of the participants had fallen asleep at least once while on duty during their career. Compared to the 4/8 watch system, the officers working the 6/6 watch system reported shorter sleep durations, more frequent nodding-off on duty (7.3% vs. 1.5%), and excessive sleepiness (32% vs. 16% with SEDS>14). Based on a logistic regression analysis, high SEDS was significantly related with probable obstructive sleep apnea (OR 5.7), the 6/6 watch system (OR 4.0), and morningness-eveningness while controlling simultaneously several individual and sleep-related factors. Subjective sleepiness (KSS) was highest at 04:00 and 06:00 h. In a multivariate analysis, the KSS was significantly related to time of day, time after awaking, sleep length, and interactions of the watch systems with age, morningness-eveningness, and Epworth sleepiness scale (ESS) score. Severe sleepiness at 04:00-06:00 h was especially problematic in the 6/6 watch system among evening types and among the bridge officers with high ESS. The results suggest the 6/6 watch system is related to a higher risk of severe sleepiness during the early morning hours compared to the 4/8 and the other watch systems assessed.

Immigrants' experiences of maternity care in Japan.

PubMed

Igarashi, Yukari; Horiuchi, Shigeko; Porter, Sarah E

2013-08-01

Language and cultural differences can negatively impact immigrant women's birth experience. However, little is known about their experiences in Japan's highly homogenous culture. This cross-sectional study used survey data from a purposive sampling of immigrant women from 16 hospitals in several Japanese prefectures. Meeting the criteria and recruited to this study were 804 participants consisting of 236 immigrant women: Chinese (n = 83), Brazilian (n = 62), Filipino (n = 43), South Korean (n = 29) and from variety of English speaking nations (n = 19) and 568 Japanese women. The questionnaire was prepared in six languages: Japanese (kana syllables), Chinese, English, Korean, Portuguese, and Tagalog (Filipino). Associations among quality of maternity care, Japanese literacy level, loneliness and care satisfaction were explored using analysis of variance and multiple linear regression. The valid and reliable instruments used were Quality of Care for Pregnancy, Delivery and Postpartum Questionnaire, Rapid Estimate of Adult Literacy in Medicine Japanese version, the revised UCLA Loneliness Scale-Japanese version and Care satisfaction. Care was evaluated across prenatal, labor and delivery and post-partum periods. Immigrant women scored higher than Japanese women for both positive and negative aspects. When loneliness was strongly felt, care satisfaction was lower. Some competence of Japanese literacy was more likely to obstruct positive communication with healthcare providers, and was associated with loneliness. Immigrant women rated overall care as satisfactory. Japanese literacy decreased communication with healthcare providers, and was associated with loneliness presumably because some literacy unreasonably increased health care providers' expectations of a higher level of communication.

40 CFR 125.121 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... discharge the use of which would not cause unwarranted economic impacts on the discharger, or... adverse changes in ecosystem diversity, productivity and stability of the biological community within the..., recreational, scientific or economic values which is unreasonable in relation to the benefit derived from the...

42 CFR 124.4 - Application.

Code of Federal Regulations, 2013 CFR

2013-10-01

... health care services, home health care, and design and construction economies, or through increased... accommodated in the patient charge structure of the health facility without unreasonable increases; and (iv... at such facility who are in need of hospital care. (l) Evidence that: (1) The appropriate health...

42 CFR 124.4 - Application.

Code of Federal Regulations, 2014 CFR

2014-10-01

... health care services, home health care, and design and construction economies, or through increased... accommodated in the patient charge structure of the health facility without unreasonable increases; and (iv... at such facility who are in need of hospital care. (l) Evidence that: (1) The appropriate health...

42 CFR 124.4 - Application.

Code of Federal Regulations, 2010 CFR

2010-10-01

... health care services, home health care, and design and construction economies, or through increased... accommodated in the patient charge structure of the health facility without unreasonable increases; and (iv... at such facility who are in need of hospital care. (l) Evidence that: (1) The appropriate health...

42 CFR 124.4 - Application.

Code of Federal Regulations, 2011 CFR

2011-10-01

... health care services, home health care, and design and construction economies, or through increased... accommodated in the patient charge structure of the health facility without unreasonable increases; and (iv... at such facility who are in need of hospital care. (l) Evidence that: (1) The appropriate health...

42 CFR 124.4 - Application.

Code of Federal Regulations, 2012 CFR

2012-10-01

... health care services, home health care, and design and construction economies, or through increased... accommodated in the patient charge structure of the health facility without unreasonable increases; and (iv... at such facility who are in need of hospital care. (l) Evidence that: (1) The appropriate health...

Report: EPA Needs a Coordinated Plan to Oversee Its Toxic Substances Control Act Responsibilities

EPA Pesticide Factsheets

Report #10-P-0066, February 17, 2010. EPA does not have integrated procedures and measures in place to ensure that new chemicals entering commerce do not pose an unreasonable risk to human health and the environment.

Managing Crises.

ERIC Educational Resources Information Center

Eggen, Jerald D.; Mackenzie, R. Alec

1987-01-01

To avoid emergency-driven work environments, crises should be anticipated to the extent possible; steps should be taken to prevent them or limit their consequences. Crises have both internal (personal) and external causes based on poor performance, unreasonable demands, or shifting priorities. Administrators need to cushion deadlines, clarify…

ASSESSMENT OF CHLORPYRIFOS EXPOSURE BY PASSIVE DOSIMETRY AND BIOMONITORING IN PESTICIDE WORKERS

EPA Science Inventory

Under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the U.S. Environmental Protection Agency (EPA) has the authority to regulate the use of pesticides to prevent unreasonable adverse human health effects associated with pesticide exposure. Accordingly, the EPA...

7 CFR 1735.61 - Approval criteria.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Whether the merger or acquisition may result in any relinquishment, impairment, or waiver of a right or... Government as note holder; and (4) Whether the proposed purchase price and terms of an acquisition are... price unreasonable if, in RUS's opinion, it will endanger financial feasibility. ...

14 CFR 380.26 - Discrimination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Discrimination. 380.26 Section 380.26... REGULATIONS PUBLIC CHARTERS Requirements Applicable to Charter Operators § 380.26 Discrimination. No charter... unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect whatsoever. ...

14 CFR 372.22 - Discrimination.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Discrimination. 372.22 Section 372.22... REGULATIONS OVERSEAS MILITARY PERSONNEL CHARTERS Conditions and Limitations § 372.22 Discrimination. No... any unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect...

14 CFR 372.22 - Discrimination.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Discrimination. 372.22 Section 372.22... REGULATIONS OVERSEAS MILITARY PERSONNEL CHARTERS Conditions and Limitations § 372.22 Discrimination. No... any unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect...

14 CFR 380.26 - Discrimination.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Discrimination. 380.26 Section 380.26... REGULATIONS PUBLIC CHARTERS Requirements Applicable to Charter Operators § 380.26 Discrimination. No charter... unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect whatsoever. ...

14 CFR 380.26 - Discrimination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Discrimination. 380.26 Section 380.26... REGULATIONS PUBLIC CHARTERS Requirements Applicable to Charter Operators § 380.26 Discrimination. No charter... unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect whatsoever. ...

14 CFR 372.22 - Discrimination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Discrimination. 372.22 Section 372.22... REGULATIONS OVERSEAS MILITARY PERSONNEL CHARTERS Conditions and Limitations § 372.22 Discrimination. No... any unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect...

14 CFR 380.26 - Discrimination.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Discrimination. 380.26 Section 380.26... REGULATIONS PUBLIC CHARTERS Requirements Applicable to Charter Operators § 380.26 Discrimination. No charter... unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect whatsoever. ...

14 CFR 372.22 - Discrimination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Discrimination. 372.22 Section 372.22... REGULATIONS OVERSEAS MILITARY PERSONNEL CHARTERS Conditions and Limitations § 372.22 Discrimination. No... any unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect...

14 CFR 380.26 - Discrimination.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Discrimination. 380.26 Section 380.26... REGULATIONS PUBLIC CHARTERS Requirements Applicable to Charter Operators § 380.26 Discrimination. No charter... unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect whatsoever. ...

14 CFR 372.22 - Discrimination.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Discrimination. 372.22 Section 372.22... REGULATIONS OVERSEAS MILITARY PERSONNEL CHARTERS Conditions and Limitations § 372.22 Discrimination. No... any unjust discrimination or any undue or unreasonable prejudice or disadvantage in any respect...

Applesauce Gets Spicier.

ERIC Educational Resources Information Center

Bracey, Gerald W.

2000-01-01

Productivity growth (and its connections with schools) may be mysterious, but experts continue to document an expanding U.S. economy. A University of Wisconsin study described in the Fall 1999 "ERS Spectrum" found a mismatch between teachers' actual and recommended grading practices. Maybe the literature is unreasonable. (MLH)

EPA’s Lead-based Paint Enforcement Helps Protect Children and Vulnerable Communities

EPA Pesticide Factsheets

The Toxic Substances Control Act (TSCA) New and Existing Chemicals (NEC) Program is exclusively a federal program that provides for review of the risk of chemicals prior to their manufacture and importation to prevent unreasonable risk to human health

The Wonderful Gift of Mathematics

ERIC Educational Resources Information Center

Norton, Anderson

2015-01-01

This theoretical analysis addresses "the unreasonable effectiveness of mathematics in the natural sciences" (Wigner, 1960). For example, how is it that ellipses--constructed by Greek geometers nearly two millennia before Kepler used them--provide such precise models for describing planetary motion? Historical models of gravity and…

16 CFR § 1204.6 - Findings.

Code of Federal Regulations, 2013 CFR

2013-01-01

... capabilities in one or more directions than can omnidirectionals, directionals are generally more expensive and... recent history of decreasing sales, may cause a number of manufacturers, including one or two of the... technical approaches to reducing or eliminating unreasonable risks of injury associated with omnidirectional...

Study of the Behavior of a Bell-Shaped Colonic Self-Expandable NiTi Stent under Peristaltic Movements

PubMed Central

Puértolas, José A.; López, Enrique

2013-01-01

Managing bowel obstruction produced by colon cancer requires an emergency intervention to patients usually in poor conditions, and it requires creating an intestinal stoma in most cases. Regardless of that the tumor may be resectable, a two-stage surgery is mandatory. To avoid these disadvantages, endoscopic placement of self-expanding stents has been introduced more than 10 years ago, as an alternative to relieve colonic obstruction. It can be used as a bridge to elective single-stage surgery avoiding a stoma or as a definitive palliative solution in patients with irresectable tumor or poor estimated survival. Stents must be capable of exerting an adequate radial pressure on the stenosed wall, keeping in mind that stent must not move or be crushed, guaranteeing an adequate lumen when affected by peristaltic waves. A finite element simulation of bell-shaped nitinol stent functionality has been done. Catheter introduction, releasing at position, and the effect of peristaltic wave were simulated. To check the reliability of the simulation, a clinical experimentation with porcine specimens was carried out. The stent presented a good deployment and flexibility. Stent behavior was excellent, expanding from the very narrow lumen corresponding to the maximum peristaltic pressure to the complete recovery of operative lumen when the pressure disappears. PMID:23841067

Distributed mixed-integer fuzzy hierarchical programming for municipal solid waste management. Part II: scheme analysis and mechanism revelation.

PubMed

Cheng, Guanhui; Huang, Guohe; Dong, Cong; Xu, Ye; Chen, Jiapei; Chen, Xiujuan; Li, Kailong

2017-03-01

As presented in the first companion paper, distributed mixed-integer fuzzy hierarchical programming (DMIFHP) was developed for municipal solid waste management (MSWM) under complexities of heterogeneities, hierarchy, discreteness, and interactions. Beijing was selected as a representative case. This paper focuses on presenting the obtained schemes and the revealed mechanisms of the Beijing MSWM system. The optimal MSWM schemes for Beijing under various solid waste treatment policies and their differences are deliberated. The impacts of facility expansion, hierarchy, and spatial heterogeneities and potential extensions of DMIFHP are also discussed. A few of findings are revealed from the results and a series of comparisons and analyses. For instance, DMIFHP is capable of robustly reflecting these complexities in MSWM systems, especially for Beijing. The optimal MSWM schemes are of fragmented patterns due to the dominant role of the proximity principle in allocating solid waste treatment resources, and they are closely related to regulated ratios of landfilling, incineration, and composting. Communities without significant differences among distances to different types of treatment facilities are more sensitive to these ratios than others. The complexities of hierarchy and heterogeneities pose significant impacts on MSWM practices. Spatial dislocation of MSW generation rates and facility capacities caused by unreasonable planning in the past may result in insufficient utilization of treatment capacities under substantial influences of transportation costs. The problems of unreasonable MSWM planning, e.g., severe imbalance among different technologies and complete vacancy of ten facilities, should be gained deliberation of the public and the municipal or local governments in Beijing. These findings are helpful for gaining insights into MSWM systems under these complexities, mitigating key challenges in the planning of these systems, improving the related management practices, and eliminating potential socio-economic and eco-environmental issues resulting from unreasonable management.

DSM-IV and DSM-5 Prevalence of Social Anxiety Disorder in a Population Sample of Older People.

PubMed

Karlsson, Björn; Sigström, Robert; Östling, Svante; Waern, Margda; Börjesson-Hanson, Anne; Skoog, Ingmar

2016-12-01

To examine the prevalence of social anxiety disorders (SAD) with (DSM-IV) and without (DSM-5) the person's own assessment that the fear was unreasonable, in a population sample of older adults. Further, to determine whether clinical and sociodemographic correlates of SAD differ depending on the criteria applied. Cross-sectional. General population in Gothenburg, Sweden. A random population-based sample of 75- and 85-year olds (N = 1200) without dementia. Psychiatric research nurses carried out a semi-structured psychiatric examination including the Comprehensive Psychopathological Rating Scale. DSM-IV SAD was diagnosed with the Mini International Neuropsychiatric Interview. SAD was diagnosed according to DSM-IV and DSM-5 criteria. The 6-month duration criterion in DSM-5 was not applied because of lack of information. Other assessments included the Global Assessment of Functioning (GAF), the Brief Scale for Anxiety (BSA), and the Montgomery Åsberg Depression Rating Scale (MADRS). The 1-month prevalence of SAD was 2.5% (N = 30) when the unreasonable fear criterion was defined in accordance with DSM-IV and 5.1% (N = 61) when the DSM-5 criterion was applied. Clinical correlates (GAF, MADRS, and BSA) were worse in SAD cases identified by either procedure compared with all others, and ratings for those reporting unreasonable fear suggested greater (albeit nonsignificant) overall psychopathology. Shifting the judgment of how reasonable the fear was, from the individual to the clinician, doubled the prevalence of SAD. This indicates that the DSM-5 version might increase prevalence rates of SAD in the general population. Further studies strictly applying all DSM-5 criteria are needed in order to confirm these findings. Copyright © 2016 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.

A bridging stent to surgery in patients with esophageal and gastroesophageal junction cancer has a dramatic negative impact on patient survival: A retrospective cohort study through data acquired from a prospectively maintained national database.

PubMed

Kjaer, D W; Nassar, M; Jensen, L S; Svendsen, L B; Mortensen, F V

2017-02-01

This study aimed to assess the impact of esophageal stenting on postoperative complications and survival in patients with obstructing esophageal and gastroesophageal junction (GEJ) cancer. All patients treated without neoadjuvant therapy that had an R0-resection performed for esophageal and GEJ cancer between January 2003 and December 2010 were identified from a prospectively maintained database. Data on stenting, postoperative mortality, morbidity, recurrence-free survival, complications, and length of hospital stay were collected. Kaplan-Meier plots for survival and recurrence-free survival curves were constructed for R0 resected patients. Data were compared between the stent and no-stent group by nonparametric tests. Two hundred seventy three consecutive R0 resected patients with esophageal or GEJ cancer were identified. Of these patients, 63 had a stent as a bridge to surgery. The male/female ratio was 2.64 (198/75) with a median age in the stent group (SG) of 65.1 versus 64.3 in the no stent group (NSG). Patients were comparable with respect to gender, age, smoking, TNM-classification, oncological treatment, hospital stay, tumor location, and histology. The median survival in the SG was 11.6 months compared with 21.3 months for patients treated without a bridging stent (P < 0.001). There were no statistically significant differences in 30-day mortality between the two groups, but NSG patients exhibited a significantly better two-year survival (P = 0.017). The median recurrence-free survival was 9.1 months for the SG compared with 15.2 months for the NSG. The use of a stent as a bridging procedure to surgery in patients treated without neaoadjuvant therapy for an esophageal or GEJ cancer that later underwent R0 resection decreased the two year survival and the recurrence-free survival. © 2016 International Society for Diseases of the Esophagus.

29 CFR 500.265 - Implementation by the Secretary.

Code of Federal Regulations, 2011 CFR

2011-07-01

... MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Administrative Proceedings Modification Or Vacation of....), and the time within which such presentation shall be submitted. The Secretary shall closely limit the time within which the briefs must be filed or oral presentations made, so as to avoid unreasonable...

29 CFR 500.265 - Implementation by the Secretary.

Code of Federal Regulations, 2010 CFR

2010-07-01

... MIGRANT AND SEASONAL AGRICULTURAL WORKER PROTECTION Administrative Proceedings Modification Or Vacation of....), and the time within which such presentation shall be submitted. The Secretary shall closely limit the time within which the briefs must be filed or oral presentations made, so as to avoid unreasonable...

ASSESSING CONTAMINANT SENSITIVITY OF ENDANGERED AND THREATENED SPECIES: TOXICANT CLASSES

EPA Science Inventory

Under the Federal Insecticide, Fungicide and Rodenticide Act, the Toxic Substances Control Act and the Clean Water Act, the U.S. Environmental Protection Agency (EPA) is charged with determining if the manufacture, use, or disposal of a chemical will present an unreasonable risk ...

21 CFR 119.1 - Dietary supplements containing ephedrine alkaloids.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Dietary supplements containing ephedrine alkaloids... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION DIETARY SUPPLEMENTS THAT PRESENT A SIGNIFICANT OR UNREASONABLE RISK § 119.1 Dietary supplements containing ephedrine alkaloids. Dietary supplements containing...

21 CFR 119.1 - Dietary supplements containing ephedrine alkaloids.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Dietary supplements containing ephedrine alkaloids... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION DIETARY SUPPLEMENTS THAT PRESENT A SIGNIFICANT OR UNREASONABLE RISK § 119.1 Dietary supplements containing ephedrine alkaloids. Dietary supplements containing...

21 CFR 119.1 - Dietary supplements containing ephedrine alkaloids.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Dietary supplements containing ephedrine alkaloids... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION DIETARY SUPPLEMENTS THAT PRESENT A SIGNIFICANT OR UNREASONABLE RISK § 119.1 Dietary supplements containing ephedrine alkaloids. Dietary supplements containing...

21 CFR 119.1 - Dietary supplements containing ephedrine alkaloids.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Dietary supplements containing ephedrine alkaloids... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION DIETARY SUPPLEMENTS THAT PRESENT A SIGNIFICANT OR UNREASONABLE RISK § 119.1 Dietary supplements containing ephedrine alkaloids. Dietary supplements containing...

Race, Reason and Reasonableness: Toward an "Unreasonable" Pedagogy

ERIC Educational Resources Information Center

De Lissovoy, Noah

2016-01-01

Starting from the contemporary critical-theoretical notion of an "objective violence" that organizes social reality in capitalism, including processes of systemic racism, as well as from phenomenological inquiries into processes of race and identity, this article explores the relationship between racism and reasonableness in education…

15 CFR 923.12 - Uses of regional benefit.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT COASTAL ZONE MANAGEMENT PROGRAM REGULATIONS Uses Subject to Management § 923.12 Uses of regional... regulations within the coastal zone do not unreasonably restrict or exclude land uses and water uses of...

21 CFR 119.1 - Dietary supplements containing ephedrine alkaloids.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Dietary supplements containing ephedrine alkaloids... SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION DIETARY SUPPLEMENTS THAT PRESENT A SIGNIFICANT OR UNREASONABLE RISK § 119.1 Dietary supplements containing ephedrine alkaloids. Dietary supplements containing...

24 CFR 26.44 - Protective orders.

Code of Federal Regulations, 2010 CFR

2010-04-01

... HEARING PROCEDURES Hearings Pursuant to the Administrative Procedure Act Discovery § 26.44 Protective... respect to discovery sought by an opposing party or with respect to the hearing, seeking to limit the..., or undue burden or expense because: (1) The discovery sought is unreasonably cumulative or...

75 FR 44251 - Wood Oils and Gums, and Streptomyces

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-28

..., that the pesticide can perform its intended function without unreasonable adverse effects on human health or the environment. Through this program, EPA is ensuring that each pesticide's registration is based on current scientific and other knowledge, including its effects on human health and the...

75 FR 862 - Bacillus subtilis; Registration Review Proposed Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-06

... perform its intended function without unreasonable adverse effects on human health or the environment... and other knowledge, including its effects on human health and the environment. DATES: Comments must... stakeholders including environmental, human health, farm workers; agricultural advocates; the chemical industry...

77 FR 40880 - Agrobacterium radiobacter; Registration Review Proposed Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... perform its intended function without unreasonable adverse effects on human health or the environment... and other knowledge, including its effects on human health and the environment. DATES: Comments must... range of stakeholders including environmental, human health, farm worker, and agricultural advocates...

78 FR 26935 - Data Requirements for Antimicrobial Pesticides

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-08

... human health, and environmental fate and effects of antimicrobial pesticide products. These revisions are also expected to help protect human health and the environment by providing an up-to-date... prevent the registration of pesticide products that may have unreasonable adverse effects on human health...

26 CFR 1.150-1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... material to the plan of financing include the purposes for the bonds and the structure of the financing..., structures involving windows or unreasonable allocations of bonds). (3) Exception for certain bonds financing... functionally related capital projects, and financing any clearly discrete governmental purpose). Each of these...

26 CFR 1.150-1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... material to the plan of financing include the purposes for the bonds and the structure of the financing..., structures involving windows or unreasonable allocations of bonds). (3) Exception for certain bonds financing... functionally related capital projects, and financing any clearly discrete governmental purpose). Each of these...

49 CFR 1220.5 - Waiver of requirements of these regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... would impose an unreasonable burden on the company. ... regulations may be made by the Board upon its own initiative or upon submission of a written request by the company. Each request for waiver shall demonstrate that unusual circumstances warrant a departure from...

43 CFR 36.3 - Preapplication.

Code of Federal Regulations, 2010 CFR

2010-10-01

... obtaining approval of a TUS is encouraged to establish early contact with each appropriate Federal agency so... processing of an application may be tentatively scheduled. (b) Reasonable preapplication activities in areas... permanent damage to the values for which the area was established or unreasonably interfere with other...

Legal Forum: Drug Testing in Public Schools.

ERIC Educational Resources Information Center

White, Janet M; Thomas, Stephen B.

1987-01-01

This article reviews court decisions concerning drug testing among prisoners, military personnel, public employees, and school employees. Fourth Amendment considerations of unreasonable search and seizure are discussed. In developing drug testing policies school districts must review these decisions in order to both protect individual rights and…

16 CFR 1304.1 - Scope and application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... in commerce; (2) that they present an unreasonable risk of injury; and (3) that no feasible consumer... labeled as, marketed, and sold solely for industrial use in non-consumer environments are not subject to..., hospitals, public buildings or other areas where consumers have customary access. ...

34 CFR 80.36 - Procurement.

Code of Federal Regulations, 2011 CFR

2011-07-01

... policies and procedures it uses for procurements from its non-Federal funds. The State will ensure that... will be responsible, in accordance with good administrative practice and sound business judgment, for... unreasonable requirements on firms in order for them to qualify to do business, (ii) Requiring unnecessary...

FY2016 Enforcement Actions for the Lead Renovation, Repair and Painting Rule (RRP)

EPA Pesticide Factsheets

The Toxic Substances Control Act (TSCA) New and Existing Chemicals (NEC) Program is exclusively a federal program that provides for review of the risk of chemicals prior to their manufacture and importation to prevent unreasonable risk to human health

40 CFR 154.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS SPECIAL REVIEW PROCEDURES General Provisions § 154.1 Purpose and scope. (a) Purpose. The purpose of the Special Review... registration of a pesticide product because uses of that product may cause unreasonable adverse effects on the...

Chemicals Determined Not Likely to Present an Unreasonable Risk Following Pre-Manufacture Notification Review

EPA Pesticide Factsheets

This page describes the regulatory determination EPA has made following review of pre-manufacture notifications under section 5 of TSCA, as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century law, P.L. 114-182.

Torts.

ERIC Educational Resources Information Center

Evans, William J., Jr.

The purpose of tort law is to offer remedies to individuals for harm that resulted from the unreasonable conduct of others. This chapter examines those cases reported during 1989 that involved tort claims within the school context. Tort cases discussed in this chapter are organized under the following sections: (1) negligence in regard to…

32 CFR 169a.10 - Contracts.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Contracts. 169a.10 Section 169a.10 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING COMMERCIAL ACTIVITIES PROGRAM PROCEDURES Procedures § 169a.10 Contracts. When contract cost becomes unreasonable or performance...

32 CFR 169a.10 - Contracts.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 1 2013-07-01 2013-07-01 false Contracts. 169a.10 Section 169a.10 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING COMMERCIAL ACTIVITIES PROGRAM PROCEDURES Procedures § 169a.10 Contracts. When contract cost becomes unreasonable or performance...

32 CFR 169a.10 - Contracts.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 1 2011-07-01 2011-07-01 false Contracts. 169a.10 Section 169a.10 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DEFENSE CONTRACTING COMMERCIAL ACTIVITIES PROGRAM PROCEDURES Procedures § 169a.10 Contracts. When contract cost becomes unreasonable or performance...

Report: EPA Needs Policies and Procedures to Manage Public Pesticide Petitions in a Transparent and Efficient Manner

EPA Pesticide Factsheets

Report #16-P-0019, October 27, 2015. OPP’s lack of policies and procedures to manage public pesticide petitions in a transparent and efficient manner can result in unreasonable delay lawsuits costing the agency time and resources.

36 CFR 7.96 - National Capital Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Alexandria in Virginia and Prince Georges, Charles, Anne Arundel, and Montgomery Counties in Maryland and to... provision or will not unreasonably interfere with other demonstrations or special events. (ii... will be waived by the Regional Director if the size and nature of the activity will not reasonably...

7 CFR 1486.404 - What expenditures are not eligible for program funding?

Code of Federal Regulations, 2013 CFR

2013-01-01

... research or new product development; (11) Costs of developing technical assistance proposals submitted to... not reimburse expenditures made prior to approval of a Recipient's proposal, unreasonable expenditures... graduate programs at colleges and/or universities (salaries or fees for individual students who are...

7 CFR 1486.404 - What expenditures are not eligible for program funding?

Code of Federal Regulations, 2014 CFR

2014-01-01

... research or new product development; (11) Costs of developing technical assistance proposals submitted to... not reimburse expenditures made prior to approval of a Recipient's proposal, unreasonable expenditures... graduate programs at colleges and/or universities (salaries or fees for individual students who are...

7 CFR 1486.404 - What expenditures are not eligible for program funding?

Code of Federal Regulations, 2012 CFR

2012-01-01

... research or new product development; (11) Costs of developing technical assistance proposals submitted to... not reimburse expenditures made prior to approval of a Recipient's proposal, unreasonable expenditures... graduate programs at colleges and/or universities (salaries or fees for individual students who are...

21 CFR 1271.420 - HCT/Ps offered for import.

Code of Federal Regulations, 2010 CFR

2010-04-01

... recipient for reproductive use. (d) This section does not apply to peripheral blood stem/progenitor cells... peripheral blood stem/progenitor cells may present an unreasonable risk of communicable disease transmission...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES...

20 CFR 615.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... States, the District of Columbia, the Commonwealth of Puerto Rico, and the U. S. Virgin Islands. (2...)(3)(C), means work which the individual has the physical and mental capacity to perform and which... work, or which involves an unreasonable risk to the individual's health, safety or morals; and such...

14 CFR 139.111 - Exemptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... information, views, or arguments that demonstrate that the requirements of §§ 139.317 or 139.319 would be unreasonably costly, burdensome, or impractical. (2) Information, views, or arguments provided under paragraph... passenger enplanement data for the previous 12 calendar months; (v) The type and frequency of air carrier...

Tradeoffs Associated with Fighting Terrorism.

ERIC Educational Resources Information Center

Deming, Stuart H.

1997-01-01

Elucidates the inherent conflict between national security and public safety measures necessitated by terrorism and the Fourth Amendment protections against unreasonable search and seizure. Briefly discusses the rise in terrorist activity in the 1970s and the development of airline security. Identifies several areas where personal freedom has been…

75 FR 41484 - Methyl Parathion; Registration Review Proposed Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-16

... intended function without unreasonable adverse effects on human health or the environment. Through this... knowledge, including its effects on human health and the environment. DATES: Comments must be received on or... stakeholders including environmental, human health, farm worker, and agricultural advocates; the chemical...

75 FR 57945 - Atonik and Verbenone, Registration Review Proposed Decisions; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-23

... pesticide can perform its intended function without unreasonable adverse effects on human health or the... scientific and other knowledge, including its effects on human health and the environment. DATES: Comments... stakeholders including environmental, human health, farm worker, and agricultural advocates; the chemical...

75 FR 16117 - Registration Review; Pesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

..., human health, farmworker, and agricultural advocates; the chemical industry; pesticide users; and... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticides... can still be used without unreasonable adverse effects on human health or the environment. A pesticide...

75 FR 82011 - Web-Distributed Labeling of Pesticides

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-29

... with pesticide labeling, thereby improving protection of human health and the environment from risks... pesticide products will not pose unreasonable adverse effects to human health or the environment. EPA..., when EPA amends the labeling of a pesticide product to incorporate new protections for human health or...

75 FR 44253 - Methidathion; Registration Review Proposed Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-28

... intended function without unreasonable adverse effects on human health or the environment. Through this... knowledge, including its effects on human health and the environment. DATES: Comments must be received on or... interest to a wide range of stakeholders including environmental, human health, farmworkers, and...

78 FR 77122 - Registration Review; Pesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

... effects on human health or the environment. A pesticide's registration review begins when the Agency... its intended function without unreasonable adverse effects on human health or the environment... knowledge, including its effects on human health and the environment. This document also announces the...

75 FR 16104 - Bromine Registration Review Final Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... the pesticide can perform its intended function without causing unreasonable adverse effects on human health or the environment. Through this program, EPA is ensuring that each pesticide's registration is based on current scientific and other knowledge, including its effects on human health and the...

Campus Life and Government Investigations.

ERIC Educational Resources Information Center

Shekleton, James F.

This paper discusses the proper way to conduct official government investigations on college campuses within the framework of the Fourth Amendment to the United States Constitution which protects against unreasonable searches and seizures. The article emphasizes that this amendment lays the groundwork for the limitations on the exercise of…

Book Industry Trends: College

ERIC Educational Resources Information Center

Oda, Stephanie; Sanislo, Glenn

2009-01-01

With the cost of college said to be escalating at double the rate of inflation, parents and students have voiced frustration, some think unreasonably, about textbook prices. In 2007, higher-education publishers continued to grapple with price resistance to textbooks and competition from the used-book market. This article reports that…

10 CFR 110.42 - Export licensing criteria.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the common defense and security. (2) The receiving country, after being advised of the information... such material, will be retransferred to the jurisdiction of any other country or group of countries... the case of facility exports, does not constitute an unreasonable risk to the public health and safety...

10 CFR 110.42 - Export licensing criteria.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the common defense and security. (2) The receiving country, after being advised of the information... such material, will be retransferred to the jurisdiction of any other country or group of countries... the case of facility exports, does not constitute an unreasonable risk to the public health and safety...

Testing the Limits on Drug Limits.

ERIC Educational Resources Information Center

Dowling-Sendor, Benjamin

2001-01-01

In an Oklahoma case, absence of a documented drug problem among students in nonathletic extracurricular activities led the10th Circuit Court to strike down the district's policy as unreasonable and unconstitutional. Imposing random, suspicionless drug-testing policies for all students attending school might violate the Fourth Amendment. (MLH)

21 CFR 312.10 - Waivers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE... communication means. A waiver request is required to contain at least one of the following: (1) An explanation... noncompliance would not pose a significant and unreasonable risk to human subjects of the investigation and that...

21 CFR 1271.420 - HCT/Ps offered for import.

Code of Federal Regulations, 2011 CFR

2011-04-01

... recipient for reproductive use. (d) This section does not apply to peripheral blood stem/progenitor cells... peripheral blood stem/progenitor cells may present an unreasonable risk of communicable disease transmission...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES...

21 CFR 1271.420 - HCT/Ps offered for import.

Code of Federal Regulations, 2014 CFR

2014-04-01

... recipient for reproductive use. (d) This section does not apply to peripheral blood stem/progenitor cells... peripheral blood stem/progenitor cells may present an unreasonable risk of communicable disease transmission...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES...

21 CFR 1271.420 - HCT/Ps offered for import.

Code of Federal Regulations, 2013 CFR

2013-04-01

... recipient for reproductive use. (d) This section does not apply to peripheral blood stem/progenitor cells... peripheral blood stem/progenitor cells may present an unreasonable risk of communicable disease transmission...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES...

21 CFR 1271.420 - HCT/Ps offered for import.

Code of Federal Regulations, 2012 CFR

2012-04-01

... recipient for reproductive use. (d) This section does not apply to peripheral blood stem/progenitor cells... peripheral blood stem/progenitor cells may present an unreasonable risk of communicable disease transmission...) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES...

16 CFR 1115.6 - Reporting of unreasonable risk of serious injury or death.

Code of Federal Regulations, 2010 CFR

2010-01-01

... injury or death. 1115.6 Section 1115.6 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SUBSTANTIAL PRODUCT HAZARD REPORTS General Interpretation § 1115.6..., distributor, and retailer of a consumer product distributed in commerce who obtains information which...

Low Releases and Low Exposures (LoREX) Exemption for New Chemicals Review under TSCA

EPA Pesticide Factsheets

EPA established an exemption category for certain new chemical substances with low environmental releases and human exposures. To ensure that they will not present an unreasonable risk, EPA has included a 30-day review and other conditions in the exemption

47 CFR 76.1512 - Programming information.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1512 Programming information. (a) An open video system operator shall not unreasonably discriminate in favor of itself or its affiliates... for the purpose of selecting programming on the open video system, or in the way such material or...

47 CFR 76.1512 - Programming information.

Code of Federal Regulations, 2013 CFR

2013-10-01

... MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1512 Programming information. (a) An open video system operator shall not unreasonably discriminate in favor of itself or its affiliates... for the purpose of selecting programming on the open video system, or in the way such material or...

47 CFR 76.1512 - Programming information.

Code of Federal Regulations, 2012 CFR

2012-10-01

... MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1512 Programming information. (a) An open video system operator shall not unreasonably discriminate in favor of itself or its affiliates... for the purpose of selecting programming on the open video system, or in the way such material or...

47 CFR 76.1512 - Programming information.

Code of Federal Regulations, 2014 CFR

2014-10-01

... MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1512 Programming information. (a) An open video system operator shall not unreasonably discriminate in favor of itself or its affiliates... for the purpose of selecting programming on the open video system, or in the way such material or...

Report: EPA’s Oversight of State Pesticide Inspections Needs Improvement to Better Ensure Safeguards for Workers, Public and Environment Are Enforced

EPA Pesticide Factsheets

Report #15-P-0156, May 15, 2015. Improvements in the EPA's inspection report review process will increase assurance that state inspections are preventing unreasonable risk to human health and the environment from pesticides.

40 CFR 720.65 - Acknowledgement of receipt of a notice; errors in the notice; incomplete submissions; and false...

Code of Federal Regulations, 2010 CFR

2010-07-01

... will not present an unreasonable risk of injury to health or the environment, if EPA has listed the... his or her delegate, may inform the submitter that the running of the review period will resume on the...

21 CFR 895.30 - Special effective date.

Code of Federal Regulations, 2010 CFR

2010-04-01

... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... unreasonable, direct, and substantial danger to the health of individuals, and (2) Before the date of the... injury involved is a serious one that the Commissioner believes will endanger the health of individuals...

Current and Emerging Water Distribution Main Renewal Technologies

EPA Science Inventory

The funding needed to address aging underground infrastructure renewals range as high as $325 billion over the next 20 years and with the current annual replacement rate at 0.5%, pipes are being expected to last for 200 years, which is unreasonable considering most pipes are desi...

Perl One-Liners: Bridging the Gap Between Large Data Sets and Analysis Tools.

PubMed

Hokamp, Karsten

2015-01-01

Computational analyses of biological data are becoming increasingly powerful, and researchers intending on carrying out their own analyses can often choose from a wide array of tools and resources. However, their application might be obstructed by the wide variety of different data formats that are in use, from standard, commonly used formats to output files from high-throughput analysis platforms. The latter are often too large to be opened, viewed, or edited by standard programs, potentially leading to a bottleneck in the analysis. Perl one-liners provide a simple solution to quickly reformat, filter, and merge data sets in preparation for downstream analyses. This chapter presents example code that can be easily adjusted to meet individual requirements. An online version is available at http://bioinf.gen.tcd.ie/pol.

Spectrum of histopathological changes encountered in stented colorectal carcinomas.

PubMed

Fryer, Eve; Gorissen, Kim J; Wang, Lai Mun; Guy, Richard; Chetty, Runjan

2015-03-01

Self-expanding metallic stents (SEMS) are increasingly being used in obstructing colorectal cancer (CRC) as a 'bridge to surgery', allowing conversion of potentially high-risk emergency resections to elective procedures. Stenting may cause a wide array of histological changes. We present the largest series to date of stented CRC, performed and reported at a single institution. Stented CRC specimens received in January 2006 to December 2011 were identified from our pathology database. Slides for each case were independently reviewed by two pathologists, and a consensus was reached. A total of 72 CRCs were identified, 15 at or proximal to the splenic flexure, and 57 left-sided. Thirty-six were stage pT3 and 36 were stage pT4. Perforation was observed in 14 cases. The effects of stenting on the tumour included tumour necrosis (100%) and flat ulceration (77.8%). The spectrum of changes in the background bowel included mimics of inflammatory bowel disease, tumour regression post-neoadjuvant therapy, and ischaemia. Given the inclusion of stenting of CRC as a bridge to surgery in the current NICE guidelines, we expect to see increasing numbers of such cases. In our study, a range of changes were encountered that mimic other bowel diseases, from simple fissuring to chronic inflammatory bowel disease and neoadjuvant regression change. © 2014 John Wiley & Sons Ltd.

40 CFR 162.154 - Disapproval of State registrations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... unreasonable adverse effects on man or the environment by the registered use. (ii) Refusal of the registering... (b)(1) of this section, the Administrator will make a final decision on disapproval of a State... days of its effective date, then the Administrator will make a final decision on disapproval within 90...

20 CFR 655.310 - Attestations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... school, and the course of study shall be one accredited by a State Board of Nursing (or its equivalent... 4-year college, or a diploma school. See § 655.350(b) of this part. Financing by the facility... or pay-back programs) to such persons. (ii) Unreasonableness of second step. The steps described in...

20 CFR 655.310 - Attestations.

Code of Federal Regulations, 2012 CFR

2012-04-01

... school, and the course of study shall be one accredited by a State Board of Nursing (or its equivalent... 4-year college, or a diploma school. See § 655.350(b) of this part. Financing by the facility... or pay-back programs) to such persons. (ii) Unreasonableness of second step. The steps described in...

12 CFR 509.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PRACTICE AND PROCEDURE IN ADJUDICATORY PROCEEDINGS Uniform Rules of Practice and Procedure § 509.22... administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes... common question of law or fact, unless such consolidation would cause unreasonable delay or injustice. (2...

47 CFR 76.960 - Prospective rate reductions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Prospective rate reductions. 76.960 Section 76.... Upon a finding that a rate for cable programming service or associated equipment is unreasonable, the... subscribing to the cable programming service at issue. (a) For an operator that adjusts its rates using the...

49 CFR 91.5 - Findings and recommendations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Findings and recommendations. 91.5 Section 91.5... PRACTICES § 91.5 Findings and recommendations. (a) Upon finding that a foreign government or entity imposes... review of the report and recommendations made under paragraph (b) of this section, that unreasonably...

76 FR 29963 - Rate Increase Disclosure and Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-23

... be subject to review based on the analysis of the trend in health care costs and rate increases... health insurance issuers regarding disclosure and review of unreasonable premium increases under section... Affordable Care Act (Pub. L. 111-148) was enacted on March 23, 2010; the Health Care and Education...

40 CFR 52.741 - Control strategy: Ozone control measures for Cook, DuPage, Kane, Lake, McHenry and Will Counties.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., plant, or animal life, to health, or to property, or to unreasonably interfere with the enjoyment of... designed to protect the public health and welfare codified in 40 CFR part 50 and promulgated from time to...

77 FR 43665 - Requirements for Distribution of Byproduct Material

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-25

... will not constitute an unreasonable risk to the common defense and security and to the health and... adequately ensured that the health and safety of the public were protected consistent with NRC policies... sources or devices are inherently adequate to protect health and minimize danger to life and property. The...

49 CFR 1155.27 - Board determinations under 49 U.S.C. 10909.

Code of Federal Regulations, 2010 CFR

2010-10-01

... determines that the facility at the existing or proposed location would not pose an unreasonable risk to... risk to public health, safety, or the environment, the Board shall weigh the particular facility's... comply with an environmental, public health, or public safety standard that falls under the traditional...

Blessed Unrest: The Power of Unreasonable People to Change the World

ERIC Educational Resources Information Center

Marshall, Stephanie Pace

2008-01-01

In this keynote address presented at the 2008 National Consortium for Specialized Secondary Schools of Mathematics, Science and Technology (NCSSSMST) Professional Conference, Stephanie Marshall describes what is needed to transform STEM education in today's world. While such an endeavor will take multiple systemic actions, here Marshall focuses on…

24 CFR 290.19 - Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders.

Code of Federal Regulations, 2011 CFR

2011-04-01

... PROPERTIES DISPOSITION OF MULTIFAMILY PROJECTS AND SALE OF HUD-HELD MULTIFAMILY MORTGAGES Disposition of Multifamily Projects § 290.19 Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders. The purchaser of any multifamily housing project shall not refuse unreasonably to...

24 CFR 290.19 - Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders.

Code of Federal Regulations, 2014 CFR

2014-04-01

... PROPERTIES DISPOSITION OF MULTIFAMILY PROJECTS AND SALE OF HUD-HELD MULTIFAMILY MORTGAGES Disposition of Multifamily Projects § 290.19 Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders. The purchaser of any multifamily housing project shall not refuse unreasonably to...

24 CFR 290.19 - Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders.

Code of Federal Regulations, 2010 CFR

2010-04-01

... PROPERTIES DISPOSITION OF MULTIFAMILY PROJECTS AND SALE OF HUD-HELD MULTIFAMILY MORTGAGES Disposition of Multifamily Projects § 290.19 Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders. The purchaser of any multifamily housing project shall not refuse unreasonably to...

24 CFR 290.19 - Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders.

Code of Federal Regulations, 2012 CFR

2012-04-01

... PROPERTIES DISPOSITION OF MULTIFAMILY PROJECTS AND SALE OF HUD-HELD MULTIFAMILY MORTGAGES Disposition of Multifamily Projects § 290.19 Restrictions concerning nondiscrimination against Section 8 certificate holders and voucher holders. The purchaser of any multifamily housing project shall not refuse unreasonably to...

Cognitive Neuroimaging: Cognitive Science out of the Armchair

ERIC Educational Resources Information Center

de Zubicaray, Greig I.

2006-01-01

Cognitive scientists were not quick to embrace the functional neuroimaging technologies that emerged during the late 20th century. In this new century, cognitive scientists continue to question, not unreasonably, the relevance of functional neuroimaging investigations that fail to address questions of interest to cognitive science. However, some…

10 CFR 503.35 - Inability to obtain adequate capital.

Code of Federal Regulations, 2010 CFR

2010-01-01

... capital investment, through tariffs, without unreasonably adverse economic effect on its service area... 10 Energy 4 2010-01-01 2010-01-01 false Inability to obtain adequate capital. 503.35 Section 503... New Facilities § 503.35 Inability to obtain adequate capital. (a) Eligibility. Section 212(a)(1)(D) of...

39 CFR 3050.21 - Content of the Postal Service's section 3652 report.

Code of Federal Regulations, 2011 CFR

2011-07-01

... competitive advantage for the Postal Service or any mailer. (i) For each nonpostal service, estimate its costs... unreasonable. (g) For each competitive negotiated service agreement: (1) Identify its rates and service... and by competitive product group; (2) Estimate the quality of service of each individual experimental...

19 CFR 10.213 - Articles eligible for preferential treatment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Articles Under the African Growth and Opportunity Act § 10.213 Articles eligible for preferential treatment... coarse animal hair or man-made filaments; (iii) Any combination of findings and trimmings of foreign... Customs finds that price to be unreasonable, all reasonable expenses incurred in the growth, production...

19 CFR 10.213 - Articles eligible for preferential treatment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Articles Under the African Growth and Opportunity Act § 10.213 Articles eligible for preferential treatment... coarse animal hair or man-made filaments; (iii) Any combination of findings and trimmings of foreign... Customs finds that price to be unreasonable, all reasonable expenses incurred in the growth, production...

19 CFR 10.213 - Articles eligible for preferential treatment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Articles Under the African Growth and Opportunity Act § 10.213 Articles eligible for preferential treatment... coarse animal hair or man-made filaments; (iii) Any combination of findings and trimmings of foreign... Customs finds that price to be unreasonable, all reasonable expenses incurred in the growth, production...

19 CFR 10.213 - Articles eligible for preferential treatment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Articles Under the African Growth and Opportunity Act § 10.213 Articles eligible for preferential treatment... coarse animal hair or man-made filaments; (iii) Any combination of findings and trimmings of foreign... Customs finds that price to be unreasonable, all reasonable expenses incurred in the growth, production...

19 CFR 10.213 - Articles eligible for preferential treatment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Articles Under the African Growth and Opportunity Act § 10.213 Articles eligible for preferential treatment... coarse animal hair or man-made filaments; (iii) Any combination of findings and trimmings of foreign... Customs finds that price to be unreasonable, all reasonable expenses incurred in the growth, production...

Permissive Parenting and Mental Health in College Students: Mediating Effects of Academic Entitlement

ERIC Educational Resources Information Center

Barton, Alison L.; Hirsch, Jameson K.

2016-01-01

Objective: Student mental health may suffer due to unreasonable expectations associated with academic entitlement; permissive parenting may be one source of these expectations. The authors examined the role of academic entitlement as a mediator of the relationship between permissive parenting and psychological functioning. Participants:…

25 CFR 166.910 - What happens if I do not fulfill my obligation to the BIA?

Code of Federal Regulations, 2010 CFR

2010-04-01

... GRAZING PERMITS Agriculture Education, Education Assistance, Recruitment, and Training § 166.910 What... under agriculture education programs with an obligated service requirement, and who does not accept employment or unreasonably terminates employment must repay us in accordance with the following table: If you...

32 CFR 144.6 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... OF THE ARMED FORCES ON STATE AND LOCAL JURIES § 144.6 Procedures. The Secretaries of the Military... summoned to perform State or local jury duty, the Secretary concerned, or the official to whom such authority has been delegated, shall decide if such jury duty would: (1) Interfere unreasonably with the...

40 CFR 761.20 - Prohibitions and exceptions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... present an unreasonable risk of injury to health within the United States. This finding is based upon the... any scientifically acceptable analytical method, may be significant, depending on such factors as the... burners in the automotive industry may burn used oil generated from automotive sources in used oil-fired...

40 CFR 761.20 - Prohibitions and exceptions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... present an unreasonable risk of injury to health within the United States. This finding is based upon the... any scientifically acceptable analytical method, may be significant, depending on such factors as the... burners in the automotive industry may burn used oil generated from automotive sources in used oil-fired...

75 FR 78243 - Propionic Acid and Salts, Urea Sulfate, Methidathion, and Methyl Parathion; Registration Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-15

... intended function without causing unreasonable adverse effects on human health or the environment. Through... other knowledge, including its effects on human health and the environment. FOR FURTHER INFORMATION... general, and may be of interest to a wide range of stakeholders including environmental, human health...

76 FR 17646 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-30

... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... adverse effects on human health or the environment. Registration review dockets contain information that... pesticide's registration is based on current scientific and other knowledge, including its effects on human...

76 FR 20666 - Streptomyces Strain K61, and Wood Oils and Gums; Registration Review Final Decisions; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... on human health and the environment. FOR FURTHER INFORMATION CONTACT: For pesticide specific... unreasonable adverse effects on human health or the environment. Through this program, EPA is ensuring that... stakeholders including environmental, human health, farm worker, and agricultural advocates; the chemical...

75 FR 57782 - Registration Review; Pesticide Dockets Opened for Review and Comment; Amended Work Plan for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-22

... perform its intended function without unreasonable adverse effects on human health or the environment... and other knowledge, including its effects on human health and the environment. This document also... range of stakeholders including environmental, human health, farmworker, and agricultural advocates; the...

40 CFR 1.43 - Office of Prevention, Pesticides and Toxic Substances.

Code of Federal Regulations, 2012 CFR

2012-07-01

... pesticides; special review of pesticides suspected of posing unreasonable risks to human health or the environment; monitoring of pesticide residue levels in food, humans, and nontarget fish and wildlife... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Office of Prevention, Pesticides and...

75 FR 19391 - Methamidophos; Registration Review Proposed Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-14

... intended function without unreasonable adverse effects on human health or the environment. Through this... knowledge, including its effects on human health and the environment. DATES: Comments must be received on or... general, and may be of interest to a wide range of stakeholders including environmental; human health...

76 FR 11456 - Pesticide Reregistration Performance Measures and Goals

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-02

...--a complete review of the human health and environmental effects of older pesticides originally... complete data base, and must not cause unreasonable adverse effects to human health or the environment when... health pesticide uses. During FY 2009 and FY 2010, EPA considered and approved the numbers of...

76 FR 46796 - Butylate; Registration Review Proposed Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-03

... unreasonable adverse effects on human health or the environment. Through this program, EPA is ensuring that... on human health and the environment. DATES: Comments must be received on or before October 3, 2011... stakeholders including environmental, human health, farm worker, and agricultural advocates; the chemical...

78 FR 17201 - Pesticide Chemicals; Registration Review; Draft Human Health and Ecological Risk Assessments...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-20

... these pesticides can still be used without unreasonable adverse effects on human health or the...; Registration Review; Draft Human Health and Ecological Risk Assessments; Notice of Availability AGENCY... draft human health and ecological risk assessments for the registration review of ancymidol, fosthiazate...

78 FR 8522 - Chlorpyrifos Registration Review; Preliminary Evaluation of the Potential Risk From...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... pesticide can perform its intended function without unreasonable adverse effects on human health or the... high and adverse human health impacts or environmental effects from exposure to the pesticides... knowledge, including its effects on human health and the environment. DATES: Comments must be received on or...

75 FR 80494 - Busan 74 (HPMTS); and Nithiazine; Registration Review Proposed Decisions; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-22

..., that the pesticide can perform its intended function without unreasonable adverse effects on human health or the environment. Through this program, EPA is ensuring that each pesticide's registration is based on current scientific and other knowledge, including its effects on human health and the...

75 FR 16114 - Registration Review; Biopesticides Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticide(s... its intended function without unreasonable adverse effects on human health or the environment... and other knowledge, including its effects on human health and the environment. DATES: Comments must...

75 FR 6655 - Disulfoton Registration Review Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... pesticide can perform its intended function without causing unreasonable adverse effects on human health or... current scientific and other knowledge, including its effects on human health and the environment. FOR... general, and may be of interest to a wide range of stakeholders including environmental, human health...

78 FR 38328 - Registration Review; Pesticide Dockets Opened for Review and Comment; Announcement of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-26

... high and adverse human health impacts or environmental effects from exposure to the pesticide(s... is, the pesticide can perform its intended function without unreasonable adverse effects on human... scientific and other knowledge, including its effects on human health and the environment. This document also...

75 FR 16100 - Antimicrobial Pesticide Registration Review Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticide(s... its intended function without unreasonable adverse effects on human health or the environment... knowledge, including its effects on human health and the environment. DATES: Comments must be received on or...

40 CFR 1.43 - Office of Prevention, Pesticides and Toxic Substances.

Code of Federal Regulations, 2010 CFR

2010-07-01

... pesticides; special review of pesticides suspected of posing unreasonable risks to human health or the environment; monitoring of pesticide residue levels in food, humans, and nontarget fish and wildlife... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Office of Prevention, Pesticides and...

40 CFR 1.43 - Office of Chemical Safety and Pollution Prevention.

Code of Federal Regulations, 2014 CFR

2014-07-01

... pesticides suspected of posing unreasonable risks to human health or the environment; monitoring of pesticide residue levels in food, humans, and non-target fish and wildlife; preparation of pesticide registration... principal adviser to the Administrator in matters pertaining to assessment and regulation of pesticides and...

75 FR 22788 - Garlic Oil and Capsaicin; Registration Review Proposed Decisions; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

... pesticide can perform its intended function without unreasonable adverse effects on human health or the...; human health; farm worker; agricultural advocates; the chemical industry; pesticide users; and members... scientific and other knowledge, including its effects on human health and the environment. DATES: Comments...

76 FR 79173 - Registration Review; Pesticide Dockets Opened for Review and Comment, and Notice of Availability...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... adverse human health impacts or environmental effects from exposure to the pesticides discussed in this... without unreasonable adverse effects on human health or the environment. A pesticide's registration review... adverse effects on human health or the environment. Registration review dockets contain information that...

40 CFR 1.43 - Office of Chemical Safety and Pollution Prevention.

Code of Federal Regulations, 2013 CFR

2013-07-01

... pesticides suspected of posing unreasonable risks to human health or the environment; monitoring of pesticide residue levels in food, humans, and non-target fish and wildlife; preparation of pesticide registration... principal adviser to the Administrator in matters pertaining to assessment and regulation of pesticides and...

76 FR 39399 - Chlorpyrifos Registration Review; Preliminary Human Health Risk Assessment; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-06

... Review; Preliminary Human Health Risk Assessment; Notice of Availability AGENCY: Environmental Protection... perform its intended function without unreasonable adverse effects on human health or the environment. As... pesticide's registration is based on current scientific and other knowledge, including its effects on human...

76 FR 4690 - Menthol and Propetamphos; Registration Review Proposed Decisions; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-26

... pesticide can perform its intended function without unreasonable adverse effects on human health or the... scientific and other knowledge, including its effects on human health and the environment. DATES: Comments... may be of interest to a wide range of stakeholders including environmental, human health, farm worker...

77 FR 60431 - Agrobacterium radiobacter strains K84/Kerr-84 and K1026; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

... function without causing unreasonable adverse effects on human health or the environment. Through this... knowledge, including its effects on human health and the environment. FOR FURTHER INFORMATION CONTACT: For... range of stakeholders including environmental, human health, farm worker, and agricultural advocates...

78 FR 59021 - Registration Review; Pesticide Dockets Opened for Review and Comment

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-25

... function without unreasonable adverse effects on human health or the environment. Registration review..., including its effects on human health and the environment. This document announces the Agency's intent not... general, and may be of interest to a wide range of stakeholders including environmental, human health...

40 CFR 1.43 - Office of Prevention, Pesticides and Toxic Substances.

Code of Federal Regulations, 2011 CFR

2011-07-01

... pesticides; special review of pesticides suspected of posing unreasonable risks to human health or the environment; monitoring of pesticide residue levels in food, humans, and nontarget fish and wildlife... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Office of Prevention, Pesticides and...

75 FR 56101 - Lauryl Sulfate Salts Registration Review Final Decision; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-15

... intended function without causing unreasonable adverse effects on human health or the environment. Through... other knowledge, including its effects on human health and the environment. FOR FURTHER INFORMATION... may be of interest to a wide range of stakeholders including environmental, human health, farm worker...

40 CFR 725.450 - Procedural requirements for the Tier II exemption.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ascertainable by the person that would permit EPA to determine that use of the microorganism, under the conditions specified in the request, will not present an unreasonable risk of injury to health or the... microorganism, the introduced genetic material, the physical containment and control technologies. ...

75 FR 2457 - Defense Federal Acquisition Regulation Supplement; Business Systems-Definition and Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-15

... INFORMATION: A. Background Contractor business systems and internal controls are the first line of defense against waste, fraud, and abuse. Weak control systems increase the risk of unallowable and unreasonable... Office of Management and Budget (OMB) as follows: (1) Accounting Systems--OMB Clearance 9000-0011; (2...

76 FR 28855 - Defense Federal Acquisition Regulation Supplement; Business Systems-Definition and Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... business systems and internal controls are the first line of defense against waste, fraud, and abuse. Weak control systems increase the risk of unallowable and unreasonable costs on Government contracts. To...'s accounting system rather than the adequacy of the contractor's control environment and overall...

75 FR 9599 - Notice of Public Information Collection Being Reviewed by the Federal Communications Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-03

..., Franchise Application Process. Type of Review: Extension of a currently approved collection. Form Number: N... franchising authorities from unreasonably refusing to award competitive franchises for the provision of cable... 76.41(b) requires a competitive franchise applicant to include the following information in writing...

Unreasonable Expectations: The Dilemma for Pedagogues in Delivering Policy Objectives

ERIC Educational Resources Information Center

Moloney, Mary

2010-01-01

Internationally, early childhood care and education policy is increasingly informed by the United Nations Convention on the Rights of the Child (UNCRC) (1989). In the Republic of Ireland, the importance of this convention was reflected in the National Children's Strategy (2000), espousing a "whole child perspective". This strategy served…

24 CFR 100.203 - Reasonable modifications of existing premises.

Code of Federal Regulations, 2010 CFR

2010-04-01

... before the modification, reasonable wear and tear excepted. The landlord may not increase for handicapped... before the modification, reasonable wear and tear excepted. It would be reasonable for the landlord to... condition, reasonable wear and tear excepted. However, it would be unreasonable for the landlord to require...

21 CFR 895.21 - Procedures for banning a device.

Code of Federal Regulations, 2010 CFR

2010-04-01

... continued marketing of the device as presently labeled, is important, material, or significant in relation to the benefit to the public health from its continued marketing. (2) In determining whether a device... marketing of the device presents a substantial deception or an unreasonable and substantial risk of illness...

77 FR 12299 - Notice of Receipt of Requests To Voluntarily Cancel Certain Pesticide Registrations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-29

......... Octhilinone. 002829-00139 Vinyzene DP 7000 Triclosan. 002829-00145 Vinyzene SB-30 Triclosan. 004822-00429 Waste Minders with Stangard/ Triclosan. 4. 007313-00006 Olympic Clear Wood Tributyltin oxide, Folpet... continued use of the pesticide would pose an unreasonable adverse effect on the environment. The registrants...

40 CFR 725.370 - EPA review of the TME application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... unreasonable risk of injury to health and the environment as a result of test marketing. ... Marketing § 725.370 EPA review of the TME application. General procedures for review of all submissions... with test marketing activities after receipt of EPA approval. (c) In approving a TME application, EPA...

Treatment Controversies in Autism

ERIC Educational Resources Information Center

Schreibman, Laura

2008-01-01

With the increasing numbers of children who are being diagnosed with an autism spectrum disorder there are a wide variety of treatment approaches being marketed to vulnerable parents who are desperate to help their child. However, many of these approaches have not been rigorously evaluated and can lead to false hopes, unreasonable fears, or…

Search and Seizure in the Schools

ERIC Educational Resources Information Center

Staros, Kari; Williams, Charles F.

2007-01-01

The Fourth Amendment to the U.S. Constitution protects the people of the United States from unreasonable searches and seizures. On first reading, these protections seem clearly defined. The amendment was meant to protect Americans from the kinds of random searches and seizures that the colonists experienced under British colonial rule. Under…

12 CFR 563.47 - Pension plans.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Pension plans. 563.47 Section 563.47 Banks and... and Structure § 563.47 Pension plans. (a) General. No savings association or service corporation thereof shall sponsor an employee pension plan which, because of unreasonable costs or any other reason...

Options for Replacing and Reformatting Deteriorated Materials.

ERIC Educational Resources Information Center

Banks, Jennifer

This resource guide focuses on handling library materials that are too deteriorated to benefit from other preservation treatments. Hopeless case items, that would require an unreasonable amount of conservation work to fix, can be resolved through a process of reselecting items by replacing them or reformatting them. The reselection integrates…

Performativity and Affect in Education

ERIC Educational Resources Information Center

Ruitenberg, Claudia W.

2015-01-01

This essay examines the concept of performativity in relation to what are perceived to be reasonable and unreasonable affective responses to discourse. It considers how discourse, especially in classrooms and other educational contexts, produces effects, and how it is that those effects are sometimes seen as attached to the discourse, and…

14 CFR 23.771 - Pilot compartment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Pilot compartment. 23.771 Section 23.771... Cargo Accommodations § 23.771 Pilot compartment. For each pilot compartment— (a) The compartment and its equipment must allow each pilot to perform his duties without unreasonable concentration or fatigue; (b...

14 CFR 29.771 - Pilot compartment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Pilot compartment. 29.771 Section 29.771... Pilot compartment. For each pilot compartment— (a) The compartment and its equipment must allow each pilot to perform his duties without unreasonable concentration or fatigue; (b) If there is provision for...

14 CFR 29.771 - Pilot compartment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Pilot compartment. 29.771 Section 29.771... Pilot compartment. For each pilot compartment— (a) The compartment and its equipment must allow each pilot to perform his duties without unreasonable concentration or fatigue; (b) If there is provision for...

48 CFR 52.225-10 - Notice of Buy American Act Requirement-Construction Materials.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials. 52.225-10 Section 52.225-10 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.225-10 Notice of Buy American Act Requirement—Construction Materials. As prescribed...

48 CFR 52.225-10 - Notice of Buy American Act Requirement-Construction Materials.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials. 52.225-10 Section 52.225-10 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.225-10 Notice of Buy American Act Requirement—Construction Materials. As prescribed...

48 CFR 52.225-10 - Notice of Buy American Act Requirement-Construction Materials.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials. 52.225-10 Section 52.225-10 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.225-10 Notice of Buy American Act Requirement—Construction Materials. As prescribed...

48 CFR 52.225-10 - Notice of Buy American Act Requirement-Construction Materials.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials. 52.225-10 Section 52.225-10 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.225-10 Notice of Buy American Act Requirement—Construction Materials. As prescribed...

Faculty and Student Affairs Collaboration in the Corporate University

ERIC Educational Resources Information Center

Harrison, Laura M.

2013-01-01

Faculty, student affairs professionals, and most importantly, students, are paying the price as institutions of higher education increasingly operate in a top-down manner with an over-emphasis on the bottom line. The corporatization of higher education creates lopsided reward (and punishment) systems for faculty, unreasonably stressful…

The Pogo Principle: We Have Met the Enemy, and Guess Who It Is?

ERIC Educational Resources Information Center

Blaine, Robert

1994-01-01

Despite recent criticisms, U.S. society is getting a good value for its education dollar. High schools are beset by college influences on the curriculum; special education requirements; overemphasis on student activities; unreasonable international comparisons; the influences of TV, teenage employment, and pathological behaviors; and the…

40 CFR 247.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... apply to purchases made by private party recipients (e.g., individuals, non-profit organizations) of... competition, considering such guidelines. Procuring agencies may decide not to procure such items if they are...; or are only available at an unreasonable price. [60 FR 21381, May 1, 1995, as amended at 62 FR 60973...

Minimizing Accidents and Risks in High Adventure Outdoor Pursuits.

ERIC Educational Resources Information Center

Meier, Joel

The fundamental dilemma in adventure programming is eliminating unreasonable risks to participants without also reducing levels of excitement, challenge, and stress. Most accidents are caused by a combination of unsafe conditions, unsafe acts, and error judgments. The best and only way to minimize critical human error in adventure programs is…

A Note on Causes of Effects

DTIC Science & Technology

2014-09-29

gone. Is it because I took aspirin ?”], let alone formulate conditions for its estimation in a counterfactual-free language (Pearl, 2000b, p. 429). 1...to take aspirin was unrelated to the (then hidden) values of the potential responses.” Now this additional assumption is unreasonable unless the joint

Cerebrovascular Accidents During Mechanical Circulatory Support: New Predictors of Ischemic and Hemorrhagic Strokes and Outcome.

PubMed

Izzy, Saef; Rubin, Daniel B; Ahmed, Firas S; Akbik, Feras; Renault, Simone; Sylvester, Katelyn W; Vaitkevicius, Henrikas; Smallwood, Jennifer A; Givertz, Michael M; Feske, Steven K

2018-05-01

Left ventricular assist devices (LVADs) have emerged as an effective treatment for patients with advanced heart failure refractory to medical therapy. Post-LVAD strokes are an important cause of morbidity and reduced quality of life. Data on risks that distinguish between ischemic and hemorrhagic post-LVAD strokes are limited. The aim of this study was to determine the incidence of post-LVAD ischemic and hemorrhagic strokes, their association with stroke risk factors, and their effect on mortality. Data are collected prospectively on all patients with LVADs implanted at Brigham and Women's Hospital. We added retrospectively collected clinical data for these analyses. From 2007 to 2016, 183 patients (median age, 57; 80% male) underwent implantation of HeartMate II LVAD as a bridge to transplant (52%), destination therapy (39%), or bridge to transplant candidacy (8%). A total of 48 strokes occurred in 39 patients (21%): 28 acute ischemic strokes in 24 patients (13%) and 20 intracerebral hemorrhages in 19 patients (10.3%). First events occurred at a median of 238 days from implantation (interquartile range, 93-515) among those who developed post-LVAD stroke. All but 9 patients (4.9%) were on warfarin (goal international normalized ratio, 2-3.5) and all received aspirin (81-325 mg). Patients with chronic obstructive pulmonary disease were more likely to have an ischemic stroke (odds ratio, 2.96; 95% confidence interval, 1.14-7.70). Dialysis-dependent patients showed a trend toward a higher risk of hemorrhagic stroke (odds ratio, 6.31; 95% confidence interval, 0.99-40.47). Hemorrhagic stroke was associated with higher mortality (odds ratio, 3.92; 95% confidence interval, 1.34-11.45) than ischemic stroke (odds ratio, 3.17; 95% confidence interval, 1.13-8.85). Stroke is a major cause of morbidity and mortality in patients on LVAD support. Chronic obstructive pulmonary disease increases the risk of ischemic stroke, whereas dialysis may increase the risk of hemorrhagic stroke. Although any stroke increases mortality, post-LVAD hemorrhagic stroke was associated with higher mortality compared with ischemic stroke. © 2018 American Heart Association, Inc.

Liver enzymes and histology in obese patients with obstructive sleep apnea.

PubMed

Kallwitz, Eric R; Herdegen, James; Madura, James; Jakate, Shriram; Cotler, Scott J

2007-01-01

Recent studies have shown an association between obstructive sleep apnea (OSA) and elevated liver enzymes in patients with nonalcoholic fatty liver disease (NAFLD). The aim of the current study was to compare biochemical and histologic findings in patients with NAFLD as a function of OSA status. Subjects consisted of 85 patients who had a sleep study followed by a liver biopsy performed at the time of obesity surgery. The diagnosis of OSA was based on an apnea hypopnea index of >/=15. Demographic and laboratory data were collected retrospectively. Liver biopsies were systematically evaluated for features of NAFLD including degree of steatosis, inflammation, and fibrosis. All but one patient had histologic evidence of NAFLD and 51% of the study population had OSA. A higher proportion of patients with OSA had elevated alanine aminotransferase levels (13/39) compared with those without OSA (3/34) (P=0.01). Only 19% of subjects had fibrosis on liver biopsy and still fewer (5%) had bridging fibrosis or cirrhosis. There was a trend toward a higher prevalence of OSA in patients with evidence of progressive liver disease, as indicated by inflammation plus fibrosis (11/15), compared with those with inflammation alone (22/48) (P=0.06). In obese patients with NAFLD, OSA was associated with elevated alanine aminotransferase levels and a trend toward histologic evidence of progressive liver disease.

SBAR Panel: Regulation of N-Methylpyrrolidone and Methylene Chloride in Paint and Coating Removal under Section 6(a) of the Toxic Substances Control Act

EPA Pesticide Factsheets

SBAR panel related to a rule that proposes to determine whether the continued use of NMP and methylene chloride in commercial and consumer paint and coating removers poses an unreasonable risk to human health and the environment

Unfair "Housing Regulation of Major Construction" in the Russian Federation

ERIC Educational Resources Information Center

Goncharov, Alexander I.; Inshakova, Agnessa O.; Kazachenok, Olesya P.; Dikarev, Ilya S.

2016-01-01

This research analyzes the illegal and unreasonable practice of court rulings that aim to accelerate the major construction of problematic long-delayed apartment blocks in the Russian Federation. The authors express their critical attitude to the widespread wrongful approach that violates the laws in effect and allows courts to apply…

75 FR 77869 - Notice of a Regional Waiver of Section 1605 (Buy American Requirement) of the American Recovery...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-14

... Office of Administration and Resources Management has concurred on this decision to make an exception to... ARRA Program Management Analyst, Grants and Strategic Planning Unit, Office of Water & Watersheds (OWW... unreasonable delay in its completion. Such delay would also directly conflict with a fundamental economic...

78 FR 28222 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... Insurance Rate Review and Pricing Transparency--Cycles I, II, and III; Use: Under the Section 1003 of the... the 2010 plan year, of unreasonable increases in premiums for health insurance coverage. Section 2794... health care pricing data to the public. The U.S. Department of Health and Human Services (HHS) released...

76 FR 80249 - Use of Differential Income Stream as a Consideration in Assessing the Best Method

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-23

... Differential Income Stream as a Consideration in Assessing the Best Method AGENCY: Internal Revenue Service... method in connection with a cost sharing arrangement. The text of these temporary regulations also serves... unreasonable positions in applying the income method by using relatively low licensing discount rates, and...

26 CFR 1.6694-2 - Penalty for understatement due to an unreasonable position.

Code of Federal Regulations, 2010 CFR

2010-04-01

... following examples: Example 1. An individual taxpayer hires Accountant R to prepare its income tax return. A... TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Additions to the Tax, Additional Amounts, and...) Proscribed conduct. Except as otherwise provided in this section, a tax return preparer is liable for a...

2 CFR 176.80 - Exceptions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Exceptions. 176.80 Section 176.80 Grants and... manufactured goods needed in the project. (2) Unreasonable cost. The head of the Federal department or agency... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and (2...

2 CFR 176.80 - Exceptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Exceptions. 176.80 Section 176.80 Grants and... manufactured goods needed in the project. (2) Unreasonable cost. The head of the Federal department or agency... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and (2...

2 CFR 176.80 - Exceptions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Exceptions. 176.80 Section 176.80 Grants and... project. (2) Unreasonable cost. The head of the Federal department or agency may determine that the cost... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and (2...

2 CFR 176.80 - Exceptions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Exceptions. 176.80 Section 176.80 Grants and... manufactured goods needed in the project. (2) Unreasonable cost. The head of the Federal department or agency... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and (2...

77 FR 10767 - Rate Adjustments for Indian Irrigation Projects

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

... Irrigation Project on the proposed rates about the following issues: (1) The methodology for O&M rate setting... BIA's responses are provided below. Comment: The BIA's methodology for setting the 2013 O&M assessment rate was unreasonable. Response: The methodology used by the BIA to determine the 2013 O&M assessment...

2 CFR 176.80 - Exceptions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Exceptions. 176.80 Section 176.80 Grants and... project. (2) Unreasonable cost. The head of the Federal department or agency may determine that the cost... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and (2...

13 CFR 107.1120 - General eligibility requirements for Leverage.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Enterprises in § 107.710(b). (h) Show, to the satisfaction of SBA, that your management is qualified and has..., 1996 will be provided to Smaller Enterprises (as defined in § 107.710(a)); and (ii) You must... unreasonable risk of default or loss to the United States government, based on such measurements of...

76 FR 65723 - Proposed Reissuance of the NPDES General Permit for Facilities Related to Oil and Gas Extraction...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... that regulated discharges will not cause unreasonable degradation of the marine environment, as... human health. EPA is also soliciting comments on whether or not to prohibit the discharge of produced... determining potential degradation of the marine environment in issuance of NPDES permits. These Ocean...

40 CFR 91.110 - Requirement of certification-prohibited controls.

Code of Federal Regulations, 2014 CFR

2014-07-01

... risk to public health, welfare, or safety in its operation or function. (b) You may not design your... unreasonable risk to public health, welfare, or safety while operating. For example, this would apply if the... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Requirement of certification-prohibited...

Risk and Hazard Management in High Adventure Outdoor Pursuits.

ERIC Educational Resources Information Center

Meier, Joel

The dilemma in adventure education is to eliminate unreasonable risks to participants without reducing the levels of excitement, challenge, and stress that are inherent in adventure programming. Most accidents in outdoor pursuits are caused by a combination of unsafe conditions; unsafe acts (usually on the part of the student); and error judgments…

3 CFR 8482 - Proclamation 8482 of March 5, 2010. National Consumer Protection Week, 2010

Code of Federal Regulations, 2011 CFR

2011-01-01

... responsible consumers with unreasonable costs. However, consumers must also learn to avoid predatory practices... Americans of all ages the resources they need to make wise buying decisions is the responsibility of Federal... to share information about consumer protection; and I encourage all Americans to learn more about...

The Internet's impact on EDI.

PubMed

Cummings, D; Kennedy, R; Moore, C

1997-01-01

Explosive growth of the Internet in a number of industries has created an information distribution channel that is likely to alter and leverage every aspect of electronic commerce. With the levels of IS integration and technological innovations in development in healthcare today, it is not unreasonable to predict that this industry soon will be similarly driven.

When a High Distinction Isn't Good Enough: A Review of Perfectionism and Self-Handicapping

ERIC Educational Resources Information Center

Kearns, Hugh; Forbes, Angus; Gardiner, Maria; Marshall, Kelly

2008-01-01

This paper addresses two problems which are common amongst university students, namely perfectionism and self-handicapping. Perfectionism deals with setting unreasonably high standards for one's own performance, while self-handicapping behaviours provide a possible excuse for poor performance, for example putting tasks off until the last minute.…

The Open-Door Policy: Transparency Minimizes Conflicts between School Principals and Staff

ERIC Educational Resources Information Center

Klein, Joseph

2012-01-01

Purpose: Little has been written about the contribution of organizational transparency to reduction of conflict between principals and teachers, especially when clarification justifies seemingly unreasonable demands by the administration. The purpose of this paper is to fill this gap. Design/methodology/approach: In total, 294 teachers from 59…

An Unreasonable Argument against Student Free Speech

ERIC Educational Resources Information Center

Blacker, David

2009-01-01

The U.S. Supreme Court's recent opinion in "Morse v. Frederick" (2007), perhaps better known as the "Bong Hits 4 Jesus" case, contains a widely reported concurrence by Justice Clarence Thomas. Challenging well-established precedent, Thomas argues that students should have no constitutional rights in school. In this essay David Blacker argues that,…

Application of Advanced Technology to Undergraduate Medical Education. Memorandum.

ERIC Educational Resources Information Center

Farquhar, J. A.; And Others

Advanced technology will have a great effect on medical education because it can speed up medical education and boost the quality of instruction without straining the capacity of medical schools to expand or driving costs to unreasonable levels. Six examples of an application of advanced technology to medical education are described in this…

32 CFR 144.4 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... OF THE ARMED FORCES ON STATE AND LOCAL JURIES § 144.4 Policy. It is DoD policy to permit members of... duties. For Service members stationed in the United States, serving on a State or local jury is one such civic obligation. Service members are exempt from jury duty, when it unreasonably would interfere with...

77 FR 58098 - Haier America Trading, LLC, Provisional Acceptance of a Settlement Agreement and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

... unreasonable risk of serious injury or death. Haier America was required to inform the Commission immediately... death, and that Haier America failed to timely notify the Commission in accordance with Section 15(b) of.... 23. The Agreement may be used in interpreting the Order. Understandings, agreements, representations...

76 FR 60822 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticides... perform its intended function without unreasonable adverse effects on human health or the environment... knowledge, including its effects on human health and the environment. EPA is also announcing that the docket...

75 FR 62323 - Pesticide Management and Disposal; Standards for Pesticide Containers and Containment; Change to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

... reduce the likelihood of unreasonable adverse effects on human health and the environment. The container... significant number of pesticides important to the protection of public health and the nation's food supply... achieve the environmental and human health protection goals of the statute and the Agency. EPA solicits...

75 FR 37790 - Lauryl Sulfate Salts; Antimicrobial Registration Review Final Work Plan and Proposed Registration...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-30

... function without unreasonable adverse effects on human health or the environment. Through this program, EPA..., including its effects on human health and the environment. DATES: Comments must be received on or before... interest to a wide range of stakeholders including environmental, human health, farm worker, and...

76 FR 68750 - Final National Pollutant Discharge Elimination System (NPDES) Pesticide General Permit for Point...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-07

..., pesticides will not pose unreasonable risks to human health and the environment. All new pesticides must... human health and environmental effects associated with use of the product. Under FIFRA, EPA is required... health and environmental effects and exposures. The applicant for registration of the pesticide must...

75 FR 35796 - Busan 74 (2-hydroxypropyl methanethiosulfonate); Chlorine Gas; and Dichromic Acid, et al...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

... disproportionately high and adverse human health impacts or environmental effects from exposure to the pesticide(s... without unreasonable adverse effects on human health or the environment. Registration review dockets... its effects on human health and the environment. DATES: Comments must be received on or before August...

77 FR 53781 - Safety Standard for Magnet Sets

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-04

... preliminarily that there may be an unreasonable risk of injury associated with children ingesting high-powered... during the eight months after it. A high percentage of the injuries resulted in surgeries or other... exception of the smaller sets, are sold with a container, such as a square plastic cube, a metal tin, and/or...

26 CFR 301.6404-2 - Abatement of interest.

Code of Federal Regulations, 2010 CFR

2010-04-01

... taxes) attributable in whole or in part to any unreasonable error or delay by an officer or employee of... is attributable to an officer or employee of the IRS (acting in an official capacity) being erroneous... taxpayer and the IRS. Before the notice of deficiency is prepared and reviewed, a clerical employee...

When Innovation Holds Learning and Undertaking in a Close Embrace

ERIC Educational Resources Information Center

Formica, Piero

2015-01-01

In this article, Piero Formica considers how new approaches to the notion of the university exemplify the value of creative ignorance in driving entrepreneurship and promoting a new culture of innovation based on blue sky science and open-mindedness. He takes the examples of the Minerva Schools, the Unreasonable Institute and the Singularity…

In Addition Afterschool Mathematics Program: Principles, Practice, and Pitfalls

ERIC Educational Resources Information Center

McVarish, Judith; Birkmeier, Patricia

2004-01-01

Afterschool math hours are most often spent on homework help, tutoring, drill, and test-preparation with instructors who may not be certified teachers or mathematics educators. While such "extra math help" may be of value, it is unreasonable to expect students to enjoy learning experiences based on workbook-style exercises. The In…

26 CFR 1.6694-2 - Penalty for understatement due to an unreasonable position.

Code of Federal Regulations, 2011 CFR

2011-04-01

... time the advice was given. (6) Reliance on generally accepted administrative or industry practice. The... investigate or ascertain) in the formulation of the advice, or the preparation of the return or claim for... upon information furnished by the taxpayer and information and advice furnished by another advisor...

How to Handle the Paper Load. Classroom Practices in Teaching English, 1979-1980.

ERIC Educational Resources Information Center

Stanford, Gene; And Others

This collection of 27 articles written by educators suggests to classroom teachers creative ways of teaching writing well even when confronted with unreasonably large classes. The articles are presented under six main headings: ungraded writing, teacher involvement--not evaluation, student self-editing, practice with parts, focused feedback, and…

Giving the Left Somewhere to Go

ERIC Educational Resources Information Center

Nelson, Michael

2007-01-01

This article talks about a new film entitled "An Unreasonable Man" that features the political activist Ralph Nader. The film rightly claims to be a documentary, but as the title hints, it's also a suspense movie. The film's first sequence briefly recounts Nader's much-maligned independent campaign for president in 2004. Although it shows him…

Urine Trouble: Drug Testing of Students and Teachers in Public Schools

ERIC Educational Resources Information Center

Butler, Frank

2012-01-01

Non-individualized (so-called "random") drug testing in public schools presents issues of Constitutional law on both the federal and state levels, particularly with regard to citizens' freedom from "unreasonable searches and seizures." The trend toward increasing acceptance of such testing by the courts (and particularly the U.S. Supreme Court)…

Effects of Home Care on the Quality of Circumstances of the Elderly.

ERIC Educational Resources Information Center

Caro, Francis G.; Blank, Arthur E.

Home care has not consistently proven to prevent institutionalization, reduce mortality rates, reduce hospital use, or improve functional status and morale; and indeed, these objectives may be unreasonable. Rather, the purpose of home care should be to meet immediate needs of recipients which they can no longer meet themselves. Publicly-funded…

Teacher Evaluation Ratings and Student Achievement: What's the Connection?

ERIC Educational Resources Information Center

Medlock, Ingrid Yvonne Williams

2017-01-01

Many public school districts struggle with the federal and state charge to increase student achievement while continuing to build the instructional capacity of classroom teachers. While this charge may not seem to be unreasonable, the widening achievement gap between various student subgroups as evidenced in standardized testing results presents…

48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials Under Trade Agreements. 52.225-12 Section 52.225-12 Federal Acquisition...—Construction Materials Under Trade Agreements. As prescribed in 25.1102(d)(1), insert the following provision...

48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials Under Trade Agreements. 52.225-12 Section 52.225-12 Federal Acquisition...—Construction Materials Under Trade Agreements. As prescribed in 25.1102(d)(1), insert the following provision...

48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials Under Trade Agreements. 52.225-12 Section 52.225-12 Federal Acquisition...—Construction Materials Under Trade Agreements. As prescribed in 25.1102(d)(1), insert the following provision...

48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the requirements of the Buy American Act, based on claimed unreasonable cost of domestic construction... Requirement-Construction Materials Under Trade Agreements. 52.225-12 Section 52.225-12 Federal Acquisition...—Construction Materials Under Trade Agreements. As prescribed in 25.1102(d)(1), insert the following provision...

On the Unreasonable Effectiveness of post-Newtonian Theory in Gravitational-Wave Physics

ScienceCinema

Will, Clifford M.

2017-12-22

The first indirect detection of gravitational waves involved a binary system of neutron stars.  In the future, the first direct detection may also involve binary systems -- inspiralling and merging binary neutron stars or black holes. This means that it is essential to understand in full detail the two-body system in general relativity, a notoriously difficult problem with a long history. Post-Newtonian approximation methods are thought to work only under slow motion and weak field conditions, while numerical solutions of Einstein's equations are thought to be limited to the final merger phase.  Recent results have shown that post-Newtonian approximations seem to remain unreasonably valid well into the relativistic regime, while advances in numerical relativity now permit solutions for numerous orbits before merger.  It is now possible to envision linking post-Newtonian theory and numerical relativity to obtain a complete "solution" of the general relativistic two-body problem.  These solutions will play a central role in detecting and understanding gravitational wave signals received by interferometric observatories on Earth and in space.

Mirror Numbers and Wigner's ``Unreasonable Effectiveness''

NASA Astrophysics Data System (ADS)

Berezin, Alexander

2006-04-01

Wigner's ``unreasonable effectiveness of mathematics in physics'' can be augmented by concept of mirror number (MN). It is defined as digital string infinite in both directions. Example is ()5141327182() where first 5 digits is Pi ``spelled'' backward (``mirrored'') and last 5 digits is the beginning of decimal exp1 string. Let MN be constructed from two different transcendental (or algebraically irrational) numbers, set of such MNs is Cantor-uncountable. Most MNs have contain any finite digital sequence repeated infinitely many times. In spirit of ``Contact'' (C.Sagan) each normal MN contains ``Library of Babel'' of all possible texts and patterns (J.L.Borges). Infinite at both ends, MN do not have any numerical values and, contrary to numbers written in positional systems, all digits in MNs have equal weight -- sort of ``numerological democracy''. In Pythagorean-Platonic models (space-time and physical world originating from pure numbers) idea of MN resolves paradox of ``beginning'' (or ``end'') of time. Because in MNs all digits have equal status, (quantum) randomness leads to more uniform and fully ergodic phase trajectories (cf. F.Dyson, Infinite in All Directions) .

The “unreasonable effectiveness” of stratigraphic and geomorphic experiments

NASA Astrophysics Data System (ADS)

Paola, Chris; Straub, Kyle; Mohrig, David; Reinhardt, Liam

2009-12-01

The growth of quantitative analysis and prediction in Earth-surface science has been accompanied by growth in experimental stratigraphy and geomorphology. Experimenters have grown increasingly bold in targeting landscape elements from channel reaches up to the entire erosional networks and depositional basins, often using very small facilities. The experiments produce spatial structure and kinematics that, although imperfect, compare well with natural systems despite differences of spatial scale, time scale, material properties, and number of active processes. Experiments have been particularly useful in studying a wide range of forms of self-organized (autogenic) complexity that occur in morphodynamic systems. Autogenic dynamics creates much of the spatial structure we see in the landscape and in preserved strata, and is strongly associated with sediment storage and release. The observed consistency between experimental and field systems despite large differences in governing dimensionless numbers is what we mean by "unreasonable effectiveness". We suggest that unreasonable experimental effectiveness arises from natural scale independence. We generalize existing ideas to relate internal similarity, in which a small part of a system is similar to the larger system, to external similarity, in which a small copy of a system is similar to the larger system. We propose that internal similarity implies external similarity, though not the converse. The external similarity of landscape experiments to natural landscapes suggests that natural scale independence may be even more characteristic of morphodynamics than it is of better studied cases such as turbulence. We urge a shift in emphasis in experimental stratigraphy and geomorphology away from classical dynamical scaling and towards a quantitative understanding of the origins and limits of scale independence. Other research areas with strong growth potential in experimental surface dynamics include physical-biotic interactions, cohesive effects, stochastic processes, the interplay of structural and geomorphic self-organization, extraction of quantitative process information from landscape and stratigraphic records, and closer interaction between experimentation and theory.

Prostatron 30-minute update: where do we stand

NASA Astrophysics Data System (ADS)

Ulchaker, James C.; Albani, Justin

2003-06-01

The urologic management of benign prostatic hyperplasia (BPH) beyond pharmaco-therapy has changed dramatically over the last decade. Open prostatectomy and transurethral resection of the prostate (TURP) have been the mainstays of surgical intervention for BPH. These procedures were initially reserved for patients with obstructive uropathy, prostatic bleeding, or bladder calculi. With improved techniques and lower morbidity, TURP is currently the "gold standard" of treatment for patients with BPH and troubling lower urinary tract symptoms (LUTS), and patients are being treated prior to the development of these adverse sequelae. Nevertheless, TURP is still major surgery, requiring either a spinal or general anesthetic and an inpatient hospital stay. Furthermore, TURP is not uniformly successful. Up to 30% of patients report dissatisfaction from the procedure. Complications have been well described and include bleeding, bladder-neck contracture, erectile dysfunction retrograde ejaculation, urinary incontinence, and fluid/electrolyte imbalance (post-TUR syndrome). The mortality rate for TURP is approx. 2 - 10/1000 cases. Over the past decade, the number of TURPs being performed has been decreasing as minimally invasive therapies, including alpha-adrenergic blockers, are being used as "first-line" management with increasing frequency and success. In addition, urologists no longer just treat ill patients in urinary retention. The treatment paradigm has evolved to include patients with persistently troubling symptoms of bladder-outlet obstruction, prior to the development of such adverse sequelae. Furthermore, patients see the care of a urologist on an elective basis, and they frequently wish to avoid surgery. As described in prior chapters, advancements in our understanding of the pathophysiology of BPH have led toimprovements in its medical management and have delayed or precluded surgery in many patients. However, when pharmacotherapy fails, further treatment options need to be discussed. Minimally invasive therapies for BPH have evolved out of this need to "bridge the gap" between medical and surgical managment. This chapter describes the current modalities of minimally invasive treatment for benign prostatic obstruction caused by prostatic lobar hyperplasia, and their respective roles in our office practice.

A novel method of edema fluid drainage in obstructive lymphedema of limbs by implantation of hydrophobic silicone tubes.

PubMed

Olszewski, Waldemar L; Zaleska, Marzanna

2015-10-01

Lymphedema of limbs is caused by partial or total obstruction of lymphatic collectors as a consequence of skin and deep soft tissue inflammation, trauma of soft tissues and bones, lymphadenectomy, and irradiation in cancer therapy. According to the statistics of the World Health Organization, around 300 million people are affected by pathologic edema of limbs. Effective treatment of such large cohorts has been a challenge for centuries. However, none of the conservative and surgical methods applied so far proved to restore the shape and function of limbs to normal conditions. Actually, physiotherapy is the therapy of choice as a main modality or supplementary to surgical procedures divided into two groups: the bridging drainage and excisional techniques. The microsurgical operations can be performed if some parts of the peripheral collecting lymphatics remain patent and partially drain edematous regions. However, in advanced cases of lymphedema, all main lymphatics are obstructed and tissue fluid accumulates in the interstitial spaces, spontaneously forming "blind channels" or "lakes." The only solution would be to create artificial pathways for edema fluid flow away to the nonobstructed regions where absorption of fluid can take place. The aim of this study was to form artificial pathways for edema fluid flow by subcutaneous implantation of silicone tubes placed along the limb from the lower leg to the lumbar or hypogastric region. In a group of 20 patients with obstructive lymphedema of the lower limbs that developed after lymphadenectomy and irradiation of the pelvis because of uterine cancer with unsuccessful conservative therapy, implantation was done, followed by external compression as intermittent pneumatic compression and elastic support of tissues. Postoperative circumference measurements, lymphoscintigraphy, and ultrasonography of tissues were carried out during 2 years of follow-up. There was a fast decrease of calf circumference since the day of implantation during weeks by a mean 3% with stabilization afterward. Patency of tubes and accumulation of fluid around them were seen on ultrasonography and lymphoscintigraphy in all cases. No tissue cellular reaction to silicone tubes was noted. The simplicity of the surgical procedure, decrease of limb edema, and lack of tissue reaction to the implant make the method worth applying in advanced stages of lymphedema with large volumes of accumulated tissue edema fluid. Copyright © 2015 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

14 CFR 399.32 - Zone of limited suspension for domestic passenger fares.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Zone of limited suspension for domestic... and Tariffs § 399.32 Zone of limited suspension for domestic passenger fares. (a) Applicability. This... unreasonable except upon a clear showing of abuse of market power that the Board does not expect to be...

Searches of Students' Cell Phones: Case Analysis and Best Practices

ERIC Educational Resources Information Center

Nowak, Benjamin; Glenn, William J.

2017-01-01

Lower courts are beginning to grapple with challenges to students' Fourth Amendment right to be free from unreasonable search and seizure as it relates to the digital environment, cell phones in particular. Recently, lower courts in several states have applied standards set forth decades ago to decide cases involving searches of students' mobile…

Reason, Liberalism, and Democratic Education: A Deweyan Approach to Teaching about Homosexuality

ERIC Educational Resources Information Center

Petrovic, John E.

2013-01-01

Teaching about homosexuality, especially in a positive light, has long been held to be a controversial issue. There is, however, a view of the capacity for reason that finds that those who deem homosexuality to be controversial will ultimately contradict themselves, becoming unreasonable. By this standard of reason, homosexuality should be treated…

A resolution expressing the sense of the Senate that telephone service must be improved in rural areas of the United States and that no entity may unreasonably discriminate against telephone users in those areas.

THOMAS, 113th Congress

Sen. Klobuchar, Amy [D-MN

2013-05-23

Senate - 12/19/2013 Placed on Senate Legislative Calendar under General Orders. Calendar No. 276. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

20 CFR 725.702 - Claims for medical benefits only under section 11 of the Reform Act.

Code of Federal Regulations, 2011 CFR

2011-04-01

... to submit to a medical examination requested by an identified operator. The unreasonable refusal to..., to the date of filing which are attributable to medical care required as a result of the miner's... securing third party liability for medical care costs is authorized by this section. If a miner seeks...

20 CFR 725.702 - Claims for medical benefits only under section 11 of the Reform Act.

Code of Federal Regulations, 2010 CFR

2010-04-01

... to submit to a medical examination requested by an identified operator. The unreasonable refusal to..., to the date of filing which are attributable to medical care required as a result of the miner's... securing third party liability for medical care costs is authorized by this section. If a miner seeks...

Genetically Modified Crops and Nuisance: Exploring the Role of Precaution in Private Law

ERIC Educational Resources Information Center

Craik, Neil; Culver, Keith; Siebrasse, Norman

2007-01-01

This article critically considers calls for the precautionary principle to inform judicial decision making in a private law context in light of the Hoffman litigation, where it is alleged that the potential for genetic contamination from genetically modified (GM) crops causes an unreasonable interference with the rights of organic farmers to use…

75 FR 33744 - Pesticide Management and Disposal; Standards for Pesticide Containers and Containment; Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

... the likelihood of unreasonable adverse effects on human health and the environment. The container and... submitted soon. This is based on an evaluation of the resources and the time it would take for EPA to..., and the FIFRA Scientific Advisory Panel (SAP). The SAP and the Secretary of Agriculture waived review...

76 FR 20655 - American Electric Power Service Corporation v. PJM Interconnection, L.L.C.; Notice of Complaint

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... Electric Power Service Corporation v. PJM Interconnection, L.L.C.; Notice of Complaint Take notice that on... complaint against PJM Interconnection, L.L.C. (Respondent), alleging that Schedule 8.1, section D.8 to the PJM Interconnection, L.L.C. Reliability Assurance Agreement is unjust, unreasonable, and unduly...

The Caring Teacher's Guide to Discipline: Helping Young Students Learn Self-Control, Responsibility, and Respect. Second Edition.

ERIC Educational Resources Information Center

Gootman, Marilyn E.

This book provides a comprehensive guide to teaching students to do the right thing. After "Introduction: Caring Teachers Can Make a Difference," 11 chapters include: (1) "Setting the Stage for Appropriate Behavior"; (2) "Expectations, Limits, and Rules" (unreasonable barricades and how to build moderate fences); (3)…

78 FR 69472 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

... a Customer order is resting on the Exchange book at the same price. A QCC Order shall only be... unreasonably discriminatory.\\15\\ NASDAQ [sic] believes that the analytical framework adopted in the ArcaBook...), 73 FR 74770 (December 9, 2008) (SR-NYSEArca-2006-21) (``ArcaBook Order''), vacated on other grounds...

77 FR 24385 - Approval and Promulgation of Air Quality Implementation Plans; Maine; Regional Haze

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-24

... Maine's low sulfur fuel oil legislation, 38 MRSA Sec. 603-A, sub-Sec. 2(A), and to incorporate this... technology option of new Low NO X Burners with modified over-fire air (NLNB/MOFA) plus selective non... unreasonable. Comment: NPS commented that the analysis of lower sulfur fuel oil for Verso Androscoggin Power...

33 CFR 117.9 - Delaying opening of a draw.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Delaying opening of a draw. 117.9... DRAWBRIDGE OPERATION REGULATIONS General Requirements § 117.9 Delaying opening of a draw. No person shall unreasonably delay the opening of a draw after the signals required by § 117.15 have been given. Note: Trains...

Comics as Art Therapy

ERIC Educational Resources Information Center

Mulholland, Matthew J.

2004-01-01

Spider Man and the Green Lantern are not the first images that most people conjure up when someone mentions "important art." In the world of fine art, comic books are often viewed as the bottom rung of the artistic ladder. In the early half of the 1900s, such an assessment would not have been unreasonable. With their rudimentary visuals and…

24 CFR 15.204 - Consideration of demands for production of material or provision of testimony.

Code of Federal Regulations, 2010 CFR

2010-04-01

... unreasonable; (vii) Production of the material or provision of the testimony would not be required under the... production of material or provision of testimony. 15.204 Section 15.204 Housing and Urban Development Office... FREEDOM OF INFORMATION ACT AND TESTIMONY AND PRODUCTION OF INFORMATION BY HUD EMPLOYEES Production of...

New CPSC Standards Require Replacing All Cribs in Child Care Programs

ERIC Educational Resources Information Center

Karolak, Eric

2011-01-01

Consumer Product Safety Commission (CPSC) is charged with protecting the public from unreasonable risks of injury or death from some 15,000 products, including cribs, toys, and a host of other products used in early childhood and school-age programs. Smart early childhood professionals act on those recalls promptly, working in partnership with the…

41 CFR 301-70.701 - Who has the authority to grant exemptions to mandatory use of Government contractor-issued travel...

Code of Federal Regulations, 2011 CFR

2011-07-01

... through a travel charge card is impractical or imposes unreasonable burdens or costs on Federal employees... grant exemptions to mandatory use of Government contractor-issued travel charge card for official travel? 301-70.701 Section 301-70.701 Public Contracts and Property Management Federal Travel Regulation...

77 FR 74845 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-18

... pesticide product will not cause ``unreasonable adverse effects'' on humans or to the environment. Under the... registrant, that the level of pesticide residues in food and feed will be safe for human consumption, defined... requires EPA to re- assess the health and safety data for all pesticide active ingredients registered...

Participatory Technologies as Workplace Learning Tools: Employees' Perceptions and Use

ERIC Educational Resources Information Center

Francone, Mary Marada

2010-01-01

Corporate Learning and Development must align learning goals with the needs of the business it serves. In times of rapid change and limitless information, it becomes unreasonable to expect a Learning and Development group to design for and deliver all the learning its workforce needs. In response, corporate learning leaders are exploring if and…

To amend the executive compensation provisions of the Emergency Economic Stabilization Act of 2008 to prohibit unreasonable and excessive compensation and compensation not based on performance standards.

THOMAS, 111th Congress

Rep. Grayson, Alan [D-FL-8

2009-03-23

Senate - 04/23/2009 Read the second time. Placed on Senate Legislative Calendar under General Orders. Calendar No. 50. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

16 CFR 1500.18 - Banned toys and other banned articles intended for use by children.

Code of Federal Regulations, 2012 CFR

2012-01-01

.... This includes products that are pre-weighted to sink to the bottom and products that are designed to... foreseeable damage or abuse, the design or manufacture presents an unreasonable risk of personal injury or... young children while sitting, bouncing, jumping, and/or reclining, and which because of its design has...

Drugs, Strip Searches, and Educator Liability: Implications of "Safford v. Redding"

ERIC Educational Resources Information Center

Stader, David L.; Greicar, Margo B.; Stevens, David W.; Dowdy, Ray

2010-01-01

School administrators are expected to balance the need for school safety and good order with the rights of students to be free of unreasonable search of their person and property. This balance can be particularly difficult when over-the-counter or prescription drugs are involved. This article summarizes a recent U.S. Supreme Court decision that…

Urineschool: A Study of the Impact of the Earls Decision on High School Random Drug Testing Policies.

ERIC Educational Resources Information Center

Conlon, Cynthia Kelly

2003-01-01

Examines impact of Supreme Court's 2002 decision in "Board of Education v. Earls" on high school random drug-testing policies and practices. Court held that random drug-testing policy at Tecumseh, Oklahoma, school district did not violate students' Fourth Amendment right against unreasonable searches. (Contains 46 references.) (PKP)

DoD and DOS Need Better Procedures to Monitor and Expend DoD Funds for the Afghan National Police Training Program

DTIC Science & Technology

2011-07-07

charged the Government for unreasonable roundtrip airline tickets, a one day rental car and parking fees of $104 even though other transportation...purchases was based on high dollar values, and the items included equipment, parts, cell phones, catered meals, fuel, and rental vehicles listed on 10

To amend the Immigration and Nationality Act with respect to a country that denies or unreasonably delays accepting the country's nationals upon the request of the Secretary of Homeland Security.

THOMAS, 111th Congress

Rep. Castle, Michael N. [R-DE-At Large

2010-07-30

House - 09/20/2010 Referred to the Subcommittee on Immigration, Citizenship, Refugees, Border Security, and International Law. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

10 CFR 63.101 - Purpose and nature of findings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Purpose and nature of findings. 63.101 Section 63.101... REPOSITORY AT YUCCA MOUNTAIN, NEVADA Technical Criteria § 63.101 Purpose and nature of findings. (a)(1... particular, § 63.41(c) requires a finding that the issuance of a license will not constitute an unreasonable...

76 FR 28766 - Flint Hills Resources Alaska, LLC; Notice of Petition for Declaratory Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... governing transportation of crude oil on the Trans Alaskan Pipeline System (TAPS) is unjust, unreasonable... returns to TAPS after the oil has been shipped 300 miles from Prudhoe Bay to Flint Hills' North Pole... returned to TAPS for resumption of its transportation to Valdez, Alaska. Any person desiring to intervene...

The hot breath of the IRS: how trustees can avoid intermediate sanctions.

PubMed

Shifman, J C

1999-06-01

New regulations from the IRS, called "intermediate sanctions," impose stiff taxes and penalties on members of not-for-profit organizations responsible for "unreasonable" compensation. That means administrators, physicians, trustees, and others must be careful to comply with the letter of the law or risk having the IRS breathing heavily down your neck.

2 CFR 176.110 - Evaluating proposals of foreign iron, steel, and/or manufactured goods.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Evaluating proposals of foreign iron, steel... iron, steel, and/or manufactured goods. (a) If the award official receives a request for an exception based on the cost of certain domestic iron, steel, and/or manufactured goods being unreasonable, in...

2 CFR 176.110 - Evaluating proposals of foreign iron, steel, and/or manufactured goods.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Evaluating proposals of foreign iron, steel... iron, steel, and/or manufactured goods. (a) If the award official receives a request for an exception based on the cost of certain domestic iron, steel, and/or manufactured goods being unreasonable, in...

Multi-level obstruction in obstructive sleep apnoea: prevalence, severity and predictive factors.

PubMed

Phua, C Q; Yeo, W X; Su, C; Mok, P K H

2017-11-01

To characterise multi-level obstruction in terms of prevalence, obstructive sleep apnoea severity and predictive factors, and to collect epidemiological data on upper airway morphology in obstructive sleep apnoea patients. Retrospective review of 250 obstructive sleep apnoea patients. On clinical examination, 171 patients (68.4 per cent) had multi-level obstruction, 49 (19.6 per cent) had single-level obstruction and 30 (12 per cent) showed no obstruction. Within each category of obstructive sleep apnoea severity, multi-level obstruction was more prevalent. Multi-level obstruction was associated with severe obstructive sleep apnoea (more than 30 events per hour) (p = 0.001). Obstructive sleep apnoea severity increased with the number of obstruction sites (correlation coefficient = 0.303, p < 0.001). Multi-level obstruction was more likely in younger (p = 0.042), male (p = 0.045) patients, with high body mass index (more than 30 kg/m2) (p < 0.001). Palatal (p = 0.004), tongue (p = 0.026) and lateral pharyngeal wall obstructions (p = 0.006) were associated with severe obstructive sleep apnoea. Multi-level obstruction is more prevalent in obstructive sleep apnoea and is associated with increased severity. Obstruction at certain anatomical levels contributes more towards obstructive sleep apnoea severity.

Antarctic field tests of SARSAT personal locater beacons

NASA Technical Reports Server (NTRS)

Bindschadler, Robert

1987-01-01

Field tests of SARSAT personal locater beacons were conducted in the Antarctic to assess the viability of using these beacons to increase the safety of Antarctic field parties. Data were collected on the extent to which dry or wet snow, melting conditions, crevasse walls and snow bridges affected the ability of the SARSAT satellite to calculate an accurate position of the beacon. Average response time between beacon turn on and alert reception in McMurdo was between 4 and 5 hours for these tests. It is concluded that the SARSAT system is viable for Antarctic operations and it is recommended that it be implemented for future field operations. Because of obstruction of line-of-sight between beacon and satellite degrades the accuracy of the location calculation (particularly in wet snow), it is further recommended that field parties have sufficient numbers of beacons to insure that in an emergency, one will be able to operate from the surface.

Health coaching to improve self-management and quality of life for low income patients with chronic obstructive pulmonary disease (COPD): protocol for a randomized controlled trial.

PubMed

Huang, Beatrice; Willard-Grace, Rachel; De Vore, Denise; Wolf, Jessica; Chirinos, Chris; Tsao, Stephanie; Hessler, Danielle; Su, George; Thom, David H

2017-06-09

Chronic obstructive pulmonary disease (COPD) severely hinders quality of life for those affected and is costly to the health care system. Care gaps in areas such as pharmacotherapy, inhaler technique, and knowledge of disease are prevalent, particularly for vulnerable populations served by community clinics. Non-professionally licensed health coaches have been shown to be an effective and cost-efficient solution in bridging care gaps and facilitating self-management for patients with other chronic diseases, but no research to date has explored their efficacy in improving care for people living with COPD. This is multi-site, single blinded, randomized controlled trial evaluates the efficacy of health coaches to facilitate patient self-management of disease and improve quality of life for patients with moderate to severe COPD. Spirometry, survey, and an exercise capacity test are conducted at baseline and at 9 months. A short survey is administered by phone at 3 and 6 months post-enrollment. The nine month health coaching intervention focuses on enhancing disease understanding and symptom awareness, improving use of inhalers; making personalized plans to increase physical activity, smoking cessation, or otherwise improve disease management; and facilitating care coordination. The results of this study will provide evidence regarding the efficacy and feasibility of health coaching to improve self-management and quality of life for urban underserved patients with moderate to severe COPD. ClinicalTrials.gov identifier NCT02234284 . Registered 12 August 2014.

Toward a Unified Knowledge-based Society for Sustainability -- Developing a Synthesis on the Methodological Level

Treesearch

Alec A. Schaerer

2006-01-01

The debates on development manifest an increasing concern for sustainability, but as yet little awareness of the hierarchy in the ideas through which humans contribute to the problem. This gap is widened by a widespread but nevertheless unnecessary acceptance of unreasonable elements such as paradoxes, or the general fragmentation in knowledge, or allegedly general...

45 CFR 154.230 - Submission and posting of Final Justifications for unreasonable rate increases.

Code of Federal Regulations, 2011 CFR

2011-10-01

... information available to the public on its Web site for at least three years. (d) CMS will post all Final Justifications on the CMS Web site. This information will remain available to the public on the CMS Web site for... submitted in the Preliminary Justification supporting the rate increase; and (2) Prominently post on its Web...

20 CFR 725.367 - Payment of a claimant's attorney's fee by responsible operator or fund.

Code of Federal Regulations, 2012 CFR

2012-04-01

... submits a bill for medical treatment, and the party liable for the payment of benefits declines to pay the bill on the grounds that the treatment is unreasonable, or is for a condition that is not compensable... order, by the district director, administrative law judge, Board or court, before whom the work was...

20 CFR 725.367 - Payment of a claimant's attorney's fee by responsible operator or fund.

Code of Federal Regulations, 2011 CFR

2011-04-01

... submits a bill for medical treatment, and the party liable for the payment of benefits declines to pay the bill on the grounds that the treatment is unreasonable, or is for a condition that is not compensable... order, by the district director, administrative law judge, Board or court, before whom the work was...

20 CFR 725.367 - Payment of a claimant's attorney's fee by responsible operator or fund.

Code of Federal Regulations, 2014 CFR

2014-04-01

... submits a bill for medical treatment, and the party liable for the payment of benefits declines to pay the bill on the grounds that the treatment is unreasonable, or is for a condition that is not compensable... order, by the district director, administrative law judge, Board or court, before whom the work was...

20 CFR 725.367 - Payment of a claimant's attorney's fee by responsible operator or fund.

Code of Federal Regulations, 2010 CFR

2010-04-01

... submits a bill for medical treatment, and the party liable for the payment of benefits declines to pay the bill on the grounds that the treatment is unreasonable, or is for a condition that is not compensable... order, by the district director, administrative law judge, Board or court, before whom the work was...

20 CFR 725.367 - Payment of a claimant's attorney's fee by responsible operator or fund.

Code of Federal Regulations, 2013 CFR

2013-04-01

... submits a bill for medical treatment, and the party liable for the payment of benefits declines to pay the bill on the grounds that the treatment is unreasonable, or is for a condition that is not compensable... order, by the district director, administrative law judge, Board or court, before whom the work was...

78 FR 72099 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-02

... from leases in California or Alaska. Value is the average of the daily mean ANS spot prices published.... . . . (1) To calculate the daily mean spot price . . . (2) Use only the days . . . (3) You must adjust the... to your refinery and the NYMEX 330 2 660 price or ANS spot price is an unreasonable value. (1...

78 FR 14824 - Agency Information Collection Activities: Submitted for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-07

... Alaska. Value is the average of the daily mean ANS spot prices published in any ONRR-approved publication during the trading month most concurrent with the production month. (1) To calculate the daily mean spot... ANS spot price is an unreasonable value. (1) . . . you may apply to the ONRR Director to establish a...

20 CFR Appendix A to Part 617 - Standard for Claim Filing, Claimant Reporting, Job Finding, and Employment Services

Code of Federal Regulations, 2010 CFR

2010-04-01

... for: “Expenditure of all money withdrawn from an unemployment fund of such State, in the payment of... of understanding of the applicable requirements; or (4) The claimant's record shows that he has... expenditure of an unreasonable amount of time or money in traveling to the nearest facility established by the...

Employment Discrimination--Age Discrimination in Employment Act of 1967--Bona Fide Occupational Qualification--Hodgson v. Greyhound Lines, Inc.

ERIC Educational Resources Information Center

Champion, Susan Elizabeth

1975-01-01

Examines the circuit court's decision in favor of Greyhound in a suit alleging that the company's refusal to accept applications for bus driver from persons under 35 violated the Age Discrimination in Employment Act (ADEA). Submits that the decision frustrates congressional intent by permitting arbitrary and unreasonable age discrimination. (JT)

41 CFR 301-50.4 - May I be granted an exception to the required use of TMS or ETS once my agency has fully deployed...

Code of Federal Regulations, 2010 CFR

2010-07-01

... an unreasonable burden on mission accomplishment (e.g., emergency travel is involved and TMS/ETS is... Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ARRANGING FOR TRAVEL SERVICES, PAYING TRAVEL EXPENSES, AND CLAIMING REIMBURSEMENT 50-ARRANGING FOR...

41 CFR 301-50.4 - May I be granted an exception to the required use of TMS or ETS once my agency has fully deployed...

Code of Federal Regulations, 2011 CFR

2011-07-01

... an unreasonable burden on mission accomplishment (e.g., emergency travel is involved and TMS/ETS is... Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ARRANGING FOR TRAVEL SERVICES, PAYING TRAVEL EXPENSES, AND CLAIMING REIMBURSEMENT 50-ARRANGING FOR...

41 CFR 301-73.102 - May we grant a traveler an exception from required use of TMS or ETS once we have fully deployed...

Code of Federal Regulations, 2010 CFR

2010-07-01

...: (1) Such use would result in an unreasonable burden on mission accomplishment (e.g., emergency travel...-73.102 Section 301-73.102 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 73-TRAVEL PROGRAMS eTravel Service and Travel...