Effects of adjuvants for human use in systemic lupus erythematosus (SLE)-prone (New Zealand black/New Zealand white) F1 mice.

PubMed

Favoino, E; Favia, E I; Digiglio, L; Racanelli, V; Shoenfeld, Y; Perosa, F

2014-01-01

The safety of four different adjuvants was assessed in lupus-prone New Zealand black/New Zealand white (BW)F1 mice. Four groups of mice were injected intraperitoneally with incomplete Freund's adjuvant (IFA), complete Freund's adjuvant (CFA), squalene (SQU) or aluminium hydroxide (ALU). An additional group received plain phosphate-buffered saline (PBS) (UNT group). Mice were primed at week 9 and boosted every other week up to week 15. Proteinuria became detectable at weeks 17 (IFA group), 24 (CFA group), 28 (SQU and ALU groups) and 32 (UNT group). Different mean values were obtained among the groups from weeks 17 to 21 [week 17: one-way analysis of variance (anova) P = 0·016; weeks 18 and 19: P = 0·048; weeks 20 and 21: P = 0·013] being higher in the IFA group than the others [Tukey's honestly significant difference (HSD) post-test P < 0·05]. No differences in anti-DNA antibody levels were observed among groups. Anti-RNP/Sm antibody developed at week 19 in only one CFA-treated mouse. Mean mouse weight at week 18 was lower in the ALU group than the IFA (Tukey's HSD post-test P = 0·04), CFA (P = 0·01) and SQU (P < 0·0001) groups, while the mean weight in the SQU group was higher than in the IFA (P = 0·009), CFA (P = 0·013) and UNT (P = 0·005) groups. The ALU group weight decreased by almost half between weeks 29 and 31, indicating some toxic effect of ALU in the late post-immunization period. Thus, SQU was the least toxic adjuvant as it did not (i) accelerate proteinuria onset compared to IFA; (ii) induce toxicity compared to ALU or (iii) elicit anti-RNP/Sm autoantibody, as occurred in the CFA group. © 2013 British Society for Immunology.

Basic Navigator Battery: An Experimental Selection Composite for Undergraduate Navigator Training.

ERIC Educational Resources Information Center

Shanahan, Frank M.; Kantor, Jeffrey E.

High rates of attrition among students in Undergraduate Navigator Training (UNT) is a major concern for Air Training Command. The main objective of this research was to evaluate the Basic Navigator Battery (BNB), a multi-test experimental selection instrument, for its potential to increase the validity of the Air Force Officer Qualifying Test…

Changes in Library Technology and Reference Desk Statistics: Is There a Relationship?

ERIC Educational Resources Information Center

Thomsett-Scott, Beth; Reese, Patricia E.

2006-01-01

The incorporation of technology into library processes has tremendously impacted staff and users alike. The University of North Texas (UNT) Libraries is no exception. Sixteen years of reference statistics are analyzed to examine the relationships between the implementation of CD-ROMs and web-based resources and the number of reference questions.…

Spray table evaluation of insecticidal mortality for southern green stink bug, Nezara viridula L. (Pentatomidae: Heteroptera) on greenhouse-grown cotton

USDA-ARS?s Scientific Manuscript database

Insecticidal mortality of southern green stink bug, Nezara viridula on greenhouse-grown cotton was investigated on a spray table. Treatments of synthetic pyrethroids and neoniconitoids were compared with those of dicrotophos at 8 oz formulated product per acre as the producer’s standard, and an unt...

Studying Distance Students: Methods, Findings, Actions

ERIC Educational Resources Information Center

Wahl, Diane; Avery, Beth; Henry, Lisa

2013-01-01

University of North Texas (UNT) Libraries began studying the library needs of distance learners in 2009 using a variety of approaches to explore and confirm these needs as well as obtain input into how to meet them. Approaches used to date include analysis of both quantitative and qualitative responses by online students to the LibQUAL+[R] surveys…

78 FR 25349 - Policy Clarification Concerning Designation of Adjacent Coastal States for Deepwater Port License...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

... and legislative history leads to the conclusion that Congress intended that for these purposes, where...\\ United Nations Convention on the Law of the Sea, Art. 2-3, Art. 33, Dec. 10, 1982, 1833 U.N.T.S. 397. \\13... legislative history, the court concluded that the SLA ``effectively grants each State on the Pacific coast all...

The '"[H]unt for New Canadians Begins in the Classroom": The Construction and Contradictions of Canadian Policy Discourse on International Education

ERIC Educational Resources Information Center

Trilokekar, Roopa Desai; El Masri, Amira

2017-01-01

In Canada's first-ever strategy, international education (IE) is linked to immigration policy with international students (IS) recruited as "ideal" immigrants. This paper engages in policy sociology and Ball's concepts of "policy as text" and "policy as discourse" (10). It follows three stages of critical policy…

Authentic Learning Experience Prepares Preservice Students to Teach Art to Children with Special Needs

ERIC Educational Resources Information Center

Bain, Christina; Hasio, Cindy

2011-01-01

Keifer-Boyd and Kraft's (2003) article "Inclusion Policy in Practice" inspired the creation of a new art education course as well as this article. In response to their claim that preservice training should provide greater exposure to experiences with students with special needs, during the summer of 2007 a group of University of North Texas (UNT)…

Background Document for Capacity Analysis for Newly Listed ...

EPA Pesticide Factsheets

... II II II M •i n". M " " It .1 tt It ..' I!' .. II .1 It \\ tl 0 4 . • • ' i ni process ois&s.F'iCH (It t ... Num&er fen!«r //cm p»s» T) A R Unt Nutnbt ' ' 1 . V 1 1 1 1 1 1 1 1 2 i 2 2 ...

Ensiling characteristics of distillers wet grains with corn stalks and determination of the feeding potential for dairy heifers

USDA-ARS?s Scientific Manuscript database

The characteristics and feeding potential of corn distillers wet grains with solubles (DWGS) ensiled with corn stalks (CS) were evaluated in a two-part experiment. A mix of 66.7 % DWGS and 33.3 % CS (as-fed) was ensiled in two plastic silage bags. One silage bag was left untreated (UNT) and the othe...

Sourcebook of Temporal Factors Affecting Information Transfer from Visual Displays

DTIC Science & Technology

1981-06-01

moving object and take appropriate action? Obviously, these behaviors are affected not only by motion perception but by memory and motor control as...Perf., 1975, 1, 383394. Layton, B. Perceptual Noise and Aging. Psych. Bull., 1975, 82, 875- 883. LeGrand, Y. Light, colour and vision. Ch. 13, time...ligkeit intermittierender lichtreize von der flimmerfreque (Brucke-effekt,,, brightness enchancement ): Unt!rsuchungen bei verschiedener leuchtdichte

3 CFR 13491 - Executive Order 13491 of January 22, 2009. Ensuring Lawful Interrogations

Code of Federal Regulations, 2010 CFR

2010-01-01

..., 18 U.S.C. 2261A; articles 93, 124, 128, and 134 of the Uniform Code of Military Justice, 10 U.S.C... and the laws of the United States of America, in order to improve the effectiveness of human... Degrading Treatment or Punishment, December 10, 1984, 1465 U.N.T.S. 85, S. Treaty Doc. No. 100-20 (1988). (e...

RFID Student Educational Experiences at the UNT College of Engineering: A Sequential Approach to Creating a Project-Based RFID Course

ERIC Educational Resources Information Center

Vaidyanathan, V. V.; Varanasi, M. R.; Kougianos, E.; Wang, Shuping; Raman, H.

2009-01-01

This paper describes radio frequency identification (RFID) projects, designed and implemented by students in the College of Engineering at the University of North Texas, as part of their senior-design project requirement. The paper also describes an RFID-based project implemented at Rice Middle School in Plano, TX, which went on to win multiple…

Time-Resolved Infrared Reflectance Studies of the Dehydration-Induced Transformation of Uranyl Nitrate Hexahydrate to the Trihydrate Form

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Timothy J.; Sweet, Lucas E.; Meier, David E.

Uranyl nitrate is a key species in the nuclear fuel cycle. However, this species is known to exist in different states of hydration, including the hexahydrate ([UO2(NO3)2(H2O)6] often called UNH), the trihydrate [UO2(NO3)2(H2O)3 or UNT], and in very dry environments the dihydrate form [UO2(NO3)2(H2O)2]. Their relative stabilities depend on both water vapor pressure and temperature. In the 1950s and 1960s the different phases were studied by infrared transmission spectroscopy, but were limited both by instrumental resolution and by the ability to prepare the samples for transmission. We have revisited this problem using time-resolved reflectance spectroscopy, which requires no sample preparationmore » and allows dynamic analysis while the sample is exposed to a flow of N2 gas. Samples of known hydration state were prepared and confirmed via X-ray diffraction patterns of known species. In reflectance mode the hexahydrate UO2(NO3)2(H2O)6 has a distinct uranyl asymmetric stretch band at 949.0 cm-1 that shifts to shorter wavelengths and broadens as the sample desiccates and recrystallizes to the trihydrate, first as a shoulder growing in on the blue edge but ultimately results in a doublet band with reflectance peaks at 966 and 957 cm-1. The data are consistent with transformation from UNH to UNT as UNT has two inequivalent UO22+ sites. The dehydration of UO2(NO3)2(H2O)6 to UO2(NO3)2(H2O)3 is both a structural and morphological change that has the lustrous lime green UO2(NO3)2(H2O)6 crystals changing to the matte greenish yellow of the trihydrate solid. The phase transformation and crystal structures were confirmed by density functional theory calculations and optical microscopy methods, both of which showed a transformation with two distinct sites for the uranyl cation in the trihydrate, with but one in the hexahydrate.« less

Time-resolved infrared reflectance studies of the dehydration-induced transformation of uranyl nitrate hexahydrate to the trihydrate form

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Timothy J.; Sweet, Lucas E.; Meier, David E.

2015-09-08

Uranyl nitrate is a key species in the nuclear fuel cycle. However, this species is known to exist in different states of hydration, including the hexahydrate ([UO 2(NO 3) 2(H 2O) 6] often called UNH), the trihydrate [UO 2(NO 3) 2(H 2O) 3 or UNT], and in very dry environments the dihydrate form [UO 2(NO 3) 2(H 2O) 2]. Their relative stabilities depend on both water vapor pressure and temperature. In the 1950s and 1960s, the different phases were studied by infrared transmission spectroscopy but were limited both by instrumental resolution and by the ability to prepare the samples formore » transmission. We have revisited this problem using time-resolved reflectance spectroscopy, which requires no sample preparation and allows dynamic analysis while the sample is exposed to a flow of N 2 gas. Samples of known hydration state were prepared and confirmed via X-ray diffraction patterns of known species. In reflectance mode the hexahydrate UO 2(NO 3) 2(H 2O) 6 has a distinct uranyl asymmetric stretch band at 949.0 cm –1 that shifts to shorter wavelengths and broadens as the sample desiccates and recrystallizes to the trihydrate, first as a shoulder growing in on the blue edge but ultimately results in a doublet band with reflectance peaks at 966 and 957 cm –1. The data are consistent with transformation from UNH to UNT as UNT has two inequivalent UO 2 2+ sites. The dehydration of UO 2(NO 3) 2(H 2O) 6 to UO 2(NO 3) 2(H 2O) 3 is both a structural and morphological change that has the lustrous lime green UO 2(NO 3) 2(H 2O) 6 crystals changing to the matte greenish yellow of the trihydrate solid. As a result, the phase transformation and crystal structures were confirmed by density functional theory calculations and optical microscopy methods, both of which showed a transformation with two distinct sites for the uranyl cation in the trihydrate, with only one in the hexahydrate.« less

The Coast Artillery Journal. Volume 61, Number 3, September 1924

DTIC Science & Technology

1924-09-01

8217ild ""est, it was considered proper to shoot any gambler caught cheating at cards. Horse thieves were hanged without mercy. Fair play was demanded...rlo."ely uffiliuted u"’ill unt"u:n>l"(Jft e.rl’er:l1Ientul tl’orl..- in the Const Artillery fur tile PWoit .~ererul yenr.". ( Iud JUIS w:tlle.o;.:sed the

The Information Content of Picture-Text Assembly Instructions.

DTIC Science & Technology

1982-03-01

Mm *i ofsi big dart as tal hierarchy Of smu~assablle NO pa t~en,1 Is hirarchy the Produe Of a given vsamSSy hUNt PIem .1 about bere . ’" - A" W~*𔃾...I LCOL J. C. Fagnbarger , 3oulder. co .,03O9 DMRCWIIA.E CF PERSnIUMEL APPL !ED RESKARC r. John S. Drawn 101 CMOII BY DRMV XEIC PaleO Alto Research

Analysis of Antarctic Remote-Site Automatic Weather Station Data for Period January 1979 - February 1980.

DTIC Science & Technology

1982-06-01

usefulness to the Untted States Antarctic mission as managed by the National Science Foundation. Various statistical measures were applied to the reported... statistical procedures that would evolve a general meteorological picture of each of these remote sites. Primary texts used as a basis for...processed by station for monthly, seasonal and annual statistics , as appropriate. The following outlines the evaluations completed for both

Proceedings of the International Association for Development of the Information Society (IADIS) International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA) (Fort Worth, Texas, October 22-24, 2013)

ERIC Educational Resources Information Center

Sampson, Demetrios G., Ed.; Spector, J. Michael, Ed.; Ifenthaler, Dirk, Ed.; Isaias, Pedro, Ed.

2013-01-01

These proceedings contain the papers of the IADIS International Conference on Cognition and Exploratory Learning in the Digital Age (CELDA 2013), October 22-24, 2013, which has been organized by the International Association for Development of the Information Society (IADIS), co-organized by The University of North Texas (UNT), sponsored by the…

Establishing a Rational New Zealand/United States Defense Relationship

DTIC Science & Technology

1994-01-01

5500 Standard Form 298 (Rev. 2-89) Prescribed by ANSI Std. Z39-16 298-102 1~4CJC SRATGYESSAY WRCITING COMIPETITION ENTRY ESTABLISHING A RATIONAL NEW...AJBAvailability Codjes ALABAMA ABSTRACT TITLE: E lishng a Rational New Zealand/United States Defense Relationship AUTHOR.- Richard J. Newlands, Wing...Current Stetu of the New Zealand/United States Relationship 12 OutstandItg Issues .1 Toward a Rational New Zealan/Unted States Defense Relationship .16

U.S. Airline Transport Pilot International Flight Language Experiences, Report 1: Background Information and General/Pre-Flight Preparation

DTIC Science & Technology

2008-09-01

Organization Code 7 . Author(s) 8. Performing Organization Report No. Prinzo OV, Campbell A 9. Performing Organization Name and Address 10...Data Com Human Factors Workng Group. We thank all the people at Amercan, Contnental, Delta, and Unted Arlnes who were nstrumental n the...ng Plots, ( 7 ) Language Experences n Natve Englsh-Speakng Arspace/Ar- ports, (8) Natve Englsh-Speakng Controllers Com- muncatng Wth Non

Regenerative Simulation of Harris Recurrent Markov Chains.

DTIC Science & Technology

1982-07-01

Sutijle) S. TYPE OF REPORT A PERIOD COVERED REGENERATIVE SIMULATION OF HARRIS RECURRENT Technical Report MARKOV CHAINS 14. PERFORMING ORG. REPORT NUMBER...7 AD-Ag 251 STANFORD UNIV CA DEPT OF OPERATIONS RESEARCH /s i2/ REGENERATIVE SIMULATION OF HARRIS RECURRENT MARKOV CHAINS,(U) JUL 82 P W GLYNN N0001...76-C-0578 UNtLASSIFIED TR-62 NL EhhhIhEEEEEEI EEEEEIIIIIII REGENERATIVE SIMULATION OF HARRIS RECURRENT MARKOV CHAINS by Peter W. Glynn TECHNICAL

Overview of U.S. Navy Antisubmarine Warfare (ASW) Organization During the Cold War Era

DTIC Science & Technology

2008-08-12

ILLUSTRATIONS Figure Page 1 Historical Context for World War I ASW .................................................................... 2 2 Historical...positioned off the continental United States: they were engaged in anti-access tactics against our naval forces Unt d K n d mP o u to Figure 2 . Historical...President: ( 1 ) the extent and nature of the submarine threat, ( 2 ) the technical possibilities for coping with this threat, (3) the extent to which the

Semiconductor Alloy Theory.

DTIC Science & Technology

1985-09-27

REPORT & PERIOD COVERED -v Semiconductor Alloy Theory Annual 0) 84-9-1 to 85-8-31 M’) 6. PERFORMING O𔃾G. REPORT NUMBER 7. AUTHOR(@) 8. CONTRACT OR...GRANT NUMBER(s) An-Ban Chen AFOSR-84-0282 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK AREA & W R UNT NUMBERS Auburn...and the effective mass. We generalized the formula for indirect-gap alloys with multiple bands and applied it to SiGe alloy. Our results, correlated

A Study of Qualitative and Geometric Knowledge in Reasoning about Motion. Revision.

DTIC Science & Technology

1981-02-01

cpartinen of I)cfcnsc under Office of Naval Research contract N00014-80-C-0505 Acce’ Tin For F T" D/ c.,, i ’" d es -t A Stud’ of Qualitatise and...UNIT-VECTOR: ((number> (number>) UNtIT-NORMAL: ((number> (number>) PERPLNDtCULAR-EQUATIONS: ((equations>) PARABOLA REGION TYPE: PARABOLA TYPE: REGION...constraints. The mapping between domain objects and Metric Diagram elements is simple: Ball -> Point Surface -> Segment Trajectory -> Segment, Parabola

Influence of biochars, compost and iron grit, alone and in combination, on copper solubility and phytotoxicity in a Cu-contaminated soil from a wood preservation site.

PubMed

Oustriere, Nadège; Marchand, Lilian; Galland, William; Gabbon, Lunel; Lottier, Nathalie; Motelica, Mikael; Mench, Michel

2016-10-01

Two biochars, a green waste compost and iron grit were used, alone and in combination, as amendment to improve soil properties and in situ stabilize Cu in a contaminated soil (964mgCukg(-1)) from a wood preservation site. The pot experiment consisted in 9 soil treatments (% w/w): untreated Cu-contaminated soil (Unt); Unt soil amended respectively with compost (5%, C), iron grit (1%, Z), pine bark-derived biochar (1%, PB), poultry-manure-derived biochar (1%, AB), PB or AB+C (5%, PBC and ABC), and PB or AB+Z (1%, PBZ and ABZ). After a 3-month reaction period, the soil pore water (SPW) was sampled in potted soils and dwarf beans were grown for a 2-week period. In the SPW, all amendments decreased the Cu(2+) concentration, but total Cu concentration increased in all AB-amended soils due to high dissolved organic matter (DOM) concentration. No treatment improved root and shoot DW yields, which even decreased in the ABC and ABZ treatments. The PBZ treatment decreased total Cu concentration in the SPW while reducing the gap with common values for root and shoot yields of dwarf bean plants. A field trial is underway before any recommendation for the PB-based treatments. Copyright © 2016 Elsevier B.V. All rights reserved.

An International Survey of Maintenance Human Factors Programs

DTIC Science & Technology

2007-09-01

50 countres. not surprsngly, g en the orgn of the surey, many respondents (39.8%) worked wthn the unted States. howeer, respondents from...National Aviation Authority (O-NAA) 72 17.8 Transport Canada (TC) 36 8.9 Civil Aviation Safety Authority ( CASA )(Australia) 19 4.7 Airline Maint 35.0...results are splt by regulatory author- ty model (.e., cASA , eASA, FAA, Tc, and o-nAA). Keep n mnd that ths was the regulatory body that ther

Devils in the Dialogue: The Air Force and Congress

DTIC Science & Technology

2011-06-01

the United States, Article I, Section 8. 111th Cong., 1st sess., 2009, S . Doc 111-4. 118 John Haskell, Congress in Context (Philadelphia, PA...Congress. 12 January 2005. http://digital.library.unt.edu/ ark :/67531/metacrs7624/m1/1/high_res_d/98- 558_2005Jan12.pdf 141 HR 91-1570, FY71 DOD...February 2011 260 Shachtman, Noah . ―Pentagon Chief Rips Heart Out of Army‘s ‗Future‘,‖ Wired, 6 April 2009, http://www.wired.com/dangerroom/2009/04

A Comprehensive Management and Operational Study of the Cheyenne Police Department

DTIC Science & Technology

1985-10-01

Liquor law violations 4. Narcotic peddlers and addicts a. Opiates b. Marijuana c. Dangerous drugs 5. Relationship to organised crime XII. JUVENILE...WIA no comprmfise* for crime andwith relet 1460 proeecutw~n of criMinaA, 3will enf rce IL. la courteOeu4 unt approriately ’without fear or lavor, malice...Wyoming 5 The Police Department 9 Lrime Experience in Cheyenne 9 Crime Trends 13 ý.omparative Crime Rates 15 Traffic Accident Experience 17 Inplications of

Physical and Mechanical Characterization of a Nano Carbon Infused Aluminum-Matrix Composite

DTIC Science & Technology

2011-10-01

n (EBSD) a results are s f hardness correlation Vickers ha condition, opy and Im clusions in son 6061 ma num specim s and appe , which are... extrusi perties to po inum in the ference poin wever no s view of a ha ly a carbon image in ations of am rticular hea Electron B and covetic unted...as a n the were point ased veals rbon No atter ere metallogr significan grains in having g distributi area cov grains un

Exterior Ballistics of a Projectile in Vertical Flight

DTIC Science & Technology

1974-11-01

7900 1311 5.146 .0585 .18? 9 PROJECT:.i-XPIO1 MUZZLE VELCCTY-18CC(F/S) ALTITUDE VELOCITY TIME OF A:R DENSITY ORAC COUNT (FT) tF/S) -_i3HT (SrCS) tL3S...36o096 .0315 .106 277 27600 48 37.505 .0314 .106 14 I C’Z LE VELCC:TY-18CC(F/S) ALT:TU E VELCCITY TIIME OF AIR CENS:TY ORAC O UNT IT) (F/S) -LI3HT (Zt

A Retrospective Analysis of the Carter Koreanization Plan: A Case Study of a Blurred Vision

DTIC Science & Technology

1992-04-06

SS WD 0 A otrnD V19S9O WMAM Lietennt oloelHowrd .LIMEia Unte tae Am Best Available Copy UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE REPORT...long-standing, overriding aims of Kim Il Sung, the capricious and bellicose leader of the Democratic People’s Republic of Korea (DPRK), has been to...in Northeast Asia in gejneral and, given Kim Il Sung’s belligerence, on South Korean soil in particular. Since the outbreak of the Korean Wa-r the

Army Air Force Exchange Service Service (AAFES) Station Tyndall Air Force Base, Florida Final Tiered Environmental Assessment

DTIC Science & Technology

2010-04-20

Unts orl!i_gh t operations : t ~cr£_fore._l]~_i mpact~ to airspau: usc and management. Noise Increased noi se from construct ion and de mol it ion...DEP Northwest District Branch Office in Panama City confirms that a storm water managemen t system and storm water environmental resource permit...il ities and to construc t one bu ildi ng (7,320 square feet) to replace these old and inadequate fac iliti es. The new fac ili ty would include a

Assessing Man’s Impact on Wetlands,

DTIC Science & Technology

1980-12-01

AD-A94 652 ARMY MILITARY PERSONNEL CENTER ALEXANDRIA VA F/S 8/6 ASSESSZNG MAN’S IMPACT ON WE LANDS,(U) UNCLASSIFIED 0 GALLOWAY 1 A uhuhfuhfhumEIliE...EElliE mrhhmhhhhEEohE mmmmmmmmm Assessing Mns Impact on Wetlands By G.E. Galloway rpp fo f A.l - 5 UN RI pulcto N-RI7-3 D 1 i ILI ’!UNt’ Sea Grant...TITLE (and Subtitle) - - 5. TYPE OF REPORT & PERIOD COVERED /Assessing Man’s Impact on Wetlands December 1980 6. PERFORMING ORG. REPORT NUMBER 7- AU HOR

Skin Friction Measurements at a Mach Number of Three and Momentum Thickness Reynolds Numbers Up to a Half Million.

DTIC Science & Technology

1980-09-01

k ADAOGZ 826 ~~~~~~~~~AIR FORCE FLIGHT DNMC A RGTPTESNABO / / I SKIN FRICTION MEASUREMENTS AT A MACH NUMBER OF THREE AND MOMENT--ETCIU) UNCASSFIE...AT A MACH NUMBER OF THREE AND MOMENTUM THICKNESS REYNOLDS NUMEERS UP TO A HALF MILLION Anthony W. Fiore Aeromechanics Division DTIC September 1980...NOR(&) S. CONTRACT OR GRANT NUMBER (s) 9. PER ORMING ORGANIZATION NAME AND ADDRESS PROR UNT N WU Flight Dynamics Laboratory (AFWAL/FIMG)RA; WOKUNTU

Noise Control: Pile Driver Demonstration Project, Waterloo, Iowa.

DTIC Science & Technology

1981-07-01

SCHOMER CERL-08684--00-10 UNCLASSIFIED CERL-TR-N-111 Na MEuuIllllImN IiMMEIIMMMM . i ljj.25 fL l1. MICROCOP )IY RLSOUtiION TLSI CIIARi construction Unte...cycle the hammer is assisted by steam or air pressure, the hammer is called "double-acting," " compound ," or "differential" according to its specific... compound was applied in an unconstrained form in rings about 0.025 m (1 in.) thick at 2.4-m (8-ft.) intervals on the piles. As discussed in a later

Wood-derived-biochar combined with compost or iron grit for in situ stabilization of Cd, Pb, and Zn in a contaminated soil.

PubMed

Oustriere, Nadège; Marchand, Lilian; Rosette, Gabriel; Friesl-Hanl, Wolfgang; Mench, Michel

2017-03-01

In situ stabilization of Cd, Pb, and Zn in an Austrian agricultural soil contaminated by atmospheric depositions from a smelter plant was assessed with a pine bark chip-derived biochar, alone and in combination with either compost or iron grit. Biochar amendment was also trialed in an uncontaminated soil to detect any detrimental effect. The pot experiment consisted in ten soil treatments (% w/w): untreated contaminated soil (Unt); Unt soil amended with biochar alone (1%: B1; 2.5%: B2.5) and in combination: B1 and B2.5 + 5% compost (B1C and B2.5C), B1 and B2.5 + 1% iron grit (B1Z and B2.5Z); uncontaminated soil (Ctrl); Ctrl soil amended with 1 or 2.5% biochar (CtrlB1, CtrlB2.5). After a 3-month reaction period, the soil pore water (SPW) was sampled in potted soils and dwarf beans were grown for a 2-week period. The SPW Cd, Pb, and Zn concentrations decreased in all amended-contaminated soils. The biochar effects increased with its addition rate and its combination with either compost or iron grit. Shoot Cd and Zn removals by beans were reduced and shoot Cd, Pb, and Zn concentrations decreased to common values in all amended soils except the B1 soil. Decreases in the SPW Cd/Pb/Zn concentrations did not improve the root and shoot yields of plants as compared to the Ctrl soil.

Proceedings of The 1980 Army Numerical Analysis and Computers Conference (17th) Held at Moffett Field, California on 20-21 February 1980.

DTIC Science & Technology

1980-08-01

relationship would be the solution of ZIG(s) F(s)) z n u(nT) fg(t) u(t) f(nT-t) u(nT-t) dt na-to -W 1 (12) The mean value theorem of the integral...4.16) corresponds to a positive eigenvalue X of (2.12) and conversely via the relationships (4.17a) a - (4.17b) = Because a is a monotone increasing...statements show how the time dependent displacements for any location of the foundation can be found, this information is used with relationships for

Installation Restoration Program. Phase 2. Confirmation/Quantification. Stage 1. Air Force Plant 4, Fort Worth, Texas. Volume 5. Appendix A-2.

DTIC Science & Technology

1987-12-01

Limit Spiked Samale Samole ISailced C" auod R sIus’lt (SSR) esult. (SR) A-dded ( .SA) Iels: I. I 1. A.luminum 75-125 - I Z. Antimony - 3. Arsenic " I...UntKtarix *s %Control Limit Spiked Samale Sample SieiCm.,ound _ _R R esult (SSR) Re t,.- (SR) Added (SA) Z,10 1. AUlunu m 7 I I I 2. Antimonyj ____ 3...No. DATE Lab Sample) ;S4 No Katrix waot, " . n ...Central L imi Spiked Samale Samale Spiked Comnpound M Rsult: (SSR) Result (SR) jAdded (SA) XR

Al Gore did Not Invent the Internet, Hans Christian Oersted did in 1820

NASA Astrophysics Data System (ADS)

Roberts, James; Anand, Aman; Dahiya, Jai

2009-04-01

In this talk it will be shown how the simple process of a current in a wire producing ``action at a distance'' in a compass can lead to development of the telegraph, telephone, wireless communication and finally to the internet. This discovery led to the invention of a motor and an electric generator. Such simple discoveries often have profound effects on what we are able to do. A discussion of how activities based on this discovery are being used in the Regional Collaborative for Excellence in Science Teaching UNT to engage students and teachers in science activities. Hand out materials will be provided to the audience on these activities.

A Simulation Model of the Common Strategic Rotary Launcher for Availability.

DTIC Science & Technology

1984-11-01

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Jerome Lewis Duggan: A Nuclear Physicist and a Well-Known, Six-Decade Accelerator Application Conference (CAARI) Organizer

NASA Astrophysics Data System (ADS)

Del McDaniel, Floyd; Doyle, Barney L.

Jerry Duggan was an experimental MeV-accelerator-based nuclear and atomic physicist who, over the past few decades, played a key role in the important transition of this field from basic to applied physics. His fascination for and application of particle accelerators spanned almost 60 years, and led to important discoveries in the following fields: accelerator-based analysis (accelerator mass spectrometry, ion beam techniques, nuclear-based analysis, nuclear microprobes, neutron techniques); accelerator facilities, stewardship, and technology development; accelerator applications (industrial, medical, security and defense, and teaching with accelerators); applied research with accelerators (advanced synthesis and modification, radiation effects, nanosciences and technology); physics research (atomic and molecular physics, and nuclear physics); and many other areas and applications. Here we describe Jerry’s physics education at the University of North Texas (B. S. and M. S.) and Louisiana State University (Ph.D.). We also discuss his research at UNT, LSU, and Oak Ridge National Laboratory, his involvement with the industrial aspects of accelerators, and his impact on many graduate students, colleagues at UNT and other universities, national laboratories, and industry and acquaintances around the world. Along the way, we found it hard not to also talk about his love of family, sports, fishing, and other recreational activities. While these were significant accomplishments in his life, Jerry will be most remembered for his insight in starting and his industry in maintaining and growing what became one of the most diverse accelerator conferences in the world — the International Conference on the Application of Accelerators in Research and Industry, or what we all know as CAARI. Through this conference, which he ran almost single-handed for decades, Jerry came to know, and became well known by, literally thousands of atomic and nuclear physicists, accelerator engineers and vendors, medical doctors, cultural heritage experts... the list goes on and on. While thousands of his acquaintances already miss Jerry, this is being felt most by his family and us (B.D. and F.D.M).

Jerome Lewis Duggan: A Nuclear Physicist and a Well-Known, Six-Decade Accelerator Application Conference (CAARI) Organizer

NASA Astrophysics Data System (ADS)

Del McDaniel, Floyd; Doyle, Barney L.

Jerry Duggan was an experimental MeV-accelerator-based nuclear and atomic physicist who, over the past few decades, played a key role in the important transition of this field from basic to applied physics. His fascination for and application of particle accelerators spanned almost 60 years, and led to important discoveries in the following fields: accelerator-based analysis (accelerator mass spectrometry, ion beam techniques, nuclear-based analysis, nuclear microprobes, neutron techniques); accelerator facilities, stewardship, and technology development; accelerator applications (industrial, medical, security and defense, and teaching with accelerators); applied research with accelerators (advanced synthesis and modification, radiation effects, nanosciences and technology); physics research (atomic and molecular physics, and nuclear physics); and many other areas and applications. Here we describe Jerry's physics education at the University of North Texas (B. S. and M. S.) and Louisiana State University (Ph.D.). We also discuss his research at UNT, LSU, and Oak Ridge National Laboratory, his involvement with the industrial aspects of accelerators, and his impact on many graduate students, colleagues at UNT and other universities, national laboratories, and industry and acquaintances around the world. Along the way, we found it hard not to also talk about his love of family, sports, fishing, and other recreational activities. While these were significant accomplishments in his life, Jerry will be most remembered for his insight in starting and his industry in maintaining and growing what became one of the most diverse accelerator conferences in the world — the International Conference on the Application of Accelerators in Research and Industry, or what we all know as CAARI. Through this conference, which he ran almost single-handed for decades, Jerry came to know, and became well known by, literally thousands of atomic and nuclear physicists, accelerator engineers and vendors, medical doctors, cultural heritage experts... the list goes on and on. While thousands of his acquaintances already miss Jerry, this is being felt most by his family and us (B.D. and F.D.M).

Energy usage while maintaining thermal comfort: A case study of a UNT dormitory

NASA Astrophysics Data System (ADS)

Gambrell, Dusten

Campus dormitories for the University of North Texas house over 5500 students per year; each one of them requires certain comfortable living conditions while they live there. There is an inherit amount of money required in order to achieve minimal comfort levels; the cost is mostly natural gas for water and room heating and electricity for cooling, lighting and peripherals. The US Department of Energy has developed several programs to aid in performing energy simulations to help those interested design more cost effective building designs. Energy-10 is such a program that allows users to conduct whole house evaluations by reviewing and altering a few parameters such as building materials, solar heating, energy efficient windows etc. The idea of this project was to recreate a campus dormitory and try to emulate existent energy consumption then try to find ways of lowering that usage while maintaining a high level of personal comfort.

Exercise training decreases NADPH oxidase activity and restores skeletal muscle mass in heart failure rats.

PubMed

Cunha, Telma F; Bechara, Luiz R G; Bacurau, Aline V N; Jannig, Paulo R; Voltarelli, Vanessa A; Dourado, Paulo M; Vasconcelos, Andrea R; Scavone, Cristóforo; Ferreira, Júlio C B; Brum, Patricia C

2017-04-01

We have recently demonstrated that NADPH oxidase hyperactivity, NF-κB activation, and increased p38 phosphorylation lead to atrophy of glycolytic muscle in heart failure (HF). Aerobic exercise training (AET) is an efficient strategy to counteract skeletal muscle atrophy in this syndrome. Therefore, we tested whether AET would regulate muscle redox balance and protein degradation by decreasing NADPH oxidase hyperactivity and reestablishing NF-κB signaling, p38 phosphorylation, and proteasome activity in plantaris muscle of myocardial infarcted-induced HF (MI) rats. Thirty-two male Wistar rats underwent MI or fictitious surgery (SHAM) and were randomly assigned into untrained (UNT) and trained (T; 8 wk of AET on treadmill) groups. AET prevented HF signals and skeletal muscle atrophy in MI-T, which showed an improved exercise tolerance, attenuated cardiac dysfunction and increased plantaris fiber cross-sectional area. To verify the role of inflammation and redox imbalance in triggering protein degradation, circulating TNF-α levels, NADPH oxidase profile, NF-κB signaling, p38 protein levels, and proteasome activity were assessed. MI-T showed a reduced TNF-α levels, NADPH oxidase activity, and Nox2 mRNA expression toward SHAM-UNT levels. The rescue of NADPH oxidase activity induced by AET in MI rats was paralleled by reducing nuclear binding activity of the NF-κB, p38 phosphorylation, atrogin-1, mRNA levels, and 26S chymotrypsin-like proteasome activity. Taken together our data provide evidence for AET improving plantaris redox homeostasis in HF associated with a decreased NADPH oxidase, redox-sensitive proteins activation, and proteasome hyperactivity further preventing atrophy. These data reinforce the role of AET as an efficient therapy for muscle wasting in HF. NEW & NOTEWORTHY This study demonstrates, for the first time, the contribution of aerobic exercise training (AET) in decreasing muscle NADPH oxidase activity associated with reduced reactive oxygen species production and systemic inflammation, which diminish NF-κB overactivation, p38 phosphorylation, and ubiquitin proteasome system hyperactivity. These molecular changes counteract plantaris atrophy in trained myocardial infarction-induced heart failure rats. Our data provide new evidence into how AET may regulate protein degradation and thus prevent skeletal muscle atrophy. Copyright © 2017 the American Physiological Society.

The New Web Outreach Program fy the Regional Collaborative for Excellence in Science Teaching at the University of North Texas

NASA Astrophysics Data System (ADS)

Imholt, Timothy; Roberts, Jim

2001-10-01

A new effort is being undertaken by the Regional Collaborative for Excellence in Science Teaching UNT, under the direction of Dr. James A. Roberts is underway. This effort includes the utilization of the multi-media capabilities of the world wide web, and a little ingenuity to attempt to pass on information to students that not only attempts to capture their attention, but perhaps spark an interest in them about the broad realm of science. Science to students is occasionally a frightening subject. This web based approach attempts to remove the fear and anxiety, while still passing on interesting, and useful information. The website will be regularly previewed and requests for contributions of exercises that might be added and shared will be solicited. Area teachers are invited to make contributions to the effort that will enhance the learning of science and mathematics by their students through the use of the web distribution.

Charge Exchange of Ne^9+ for X-ray Emission

NASA Astrophysics Data System (ADS)

Lyons, David

2016-01-01

Using the molecular-orbital close-coupling (MOCC) method, single electron capture (SEC) cross sections were computed for Ne^9+ colliding with H.Potential energies and nonadiabatic couplings were calculated and used to obtain the MOCC cross sections which are final-quantum-state-resolved including a separation of singlet and triplet states. Atomic-orbital close-coupling, classical trajectory Monte Carlo, and multichannel Landau-Zener (MCLZ) calculations are also performed. Cross sections for more complicated targets including He, H2, N2, H2O, CO, and CO2, were obtained with the MCLZ method. The SEC results are compared with experimental and other theoretical data, where available. The SEC cross sections are being used in cascade models to predict X-ray emission spectra relevant to solar systemand astrophysical environments.D. Lyons, R. S. Cumbee, P. D. Mullen, P. C. Stancil (UGA), D. R. Schultz (UNT), P. Liebermann (Wuppertal Univ.),R. Buenker (NCSU).This work was partially supported by NASA grant NNX09AC46G.

TNR and conservation on a university campus: a political ecological perspective.

PubMed

Dombrosky, Jonathan; Wolverton, Steve

2014-01-01

How to manage the impact of free-ranging cats on native wildlife is a polarizing issue. Conservation biologists largely support domestic cat euthanasia to mitigate impacts of free-ranging cat predation on small animal populations. Above all else, animal welfare activists support the humane treatment of free-ranging cats, objecting to euthanasia. Clearly, this issue of how to control free-ranging cat predation on small animals is value laden, and both positions must be considered and comprehended to promote effective conservation. Here, two gaps in the free-ranging cat-small-animal conservation literature are addressed. First, the importance of understanding the processes of domestication and evolution and how each relates to felid behavioral ecology is discussed. The leading hypothesis to explain domestication of wildcats (Felis silvestris) relates to their behavioral ecology as a solitary predator, which made them suited for pest control in early agricultural villages of the Old World. The relationship humans once had with cats, however, has changed because today domesticated cats are usually household pets. As a result, concerns of conservation biologists may relate to cats as predators, but cat welfare proponents come from the position of assuming responsibility for free-ranging household pets (and their feral offspring). Thus, the perceptions of pet owners and other members of the general public provide an important context that frames the relationship between free-ranging cats and small animal conservation. The second part of this paper assesses the effects of an information-based conservation approach on shifting student's perception of a local Trap-Neuter-Return (TNR) program in introductory core science classes at the University of North Texas (UNT). UNT students are (knowingly or unknowingly) regularly in close proximity to a TNR program on campus that supports cat houses and feeding stations. A survey design implementing a tailored-information approach was used to communicate what TNR programs are, their goals, and the "conservationist" view of TNR programs. We gauged favorability of student responses to the goals of TNR programs prior to and after exposure to tailored information on conservation concerns related to free-ranging cats. Although these results are from a preliminary study, we suggest that an information-based approach may only be marginally effective at shifting perceptions about the conservation implications of free-ranging cats. Our position is that small animal conservation in Western societies occurs in the context of pet ownership, thus broader approaches that promote ecological understanding via environmental education are more likely to be successful than information-based approaches.

TNR and conservation on a university campus: a political ecological perspective

PubMed Central

Wolverton, Steve

2014-01-01

How to manage the impact of free-ranging cats on native wildlife is a polarizing issue. Conservation biologists largely support domestic cat euthanasia to mitigate impacts of free-ranging cat predation on small animal populations. Above all else, animal welfare activists support the humane treatment of free-ranging cats, objecting to euthanasia. Clearly, this issue of how to control free-ranging cat predation on small animals is value laden, and both positions must be considered and comprehended to promote effective conservation. Here, two gaps in the free-ranging cat—small-animal conservation literature are addressed. First, the importance of understanding the processes of domestication and evolution and how each relates to felid behavioral ecology is discussed. The leading hypothesis to explain domestication of wildcats (Felis silvestris) relates to their behavioral ecology as a solitary predator, which made them suited for pest control in early agricultural villages of the Old World. The relationship humans once had with cats, however, has changed because today domesticated cats are usually household pets. As a result, concerns of conservation biologists may relate to cats as predators, but cat welfare proponents come from the position of assuming responsibility for free-ranging household pets (and their feral offspring). Thus, the perceptions of pet owners and other members of the general public provide an important context that frames the relationship between free-ranging cats and small animal conservation. The second part of this paper assesses the effects of an information-based conservation approach on shifting student’s perception of a local Trap–Neuter–Return (TNR) program in introductory core science classes at the University of North Texas (UNT). UNT students are (knowingly or unknowingly) regularly in close proximity to a TNR program on campus that supports cat houses and feeding stations. A survey design implementing a tailored-information approach was used to communicate what TNR programs are, their goals, and the “conservationist” view of TNR programs. We gauged favorability of student responses to the goals of TNR programs prior to and after exposure to tailored information on conservation concerns related to free-ranging cats. Although these results are from a preliminary study, we suggest that an information-based approach may only be marginally effective at shifting perceptions about the conservation implications of free-ranging cats. Our position is that small animal conservation in Western societies occurs in the context of pet ownership, thus broader approaches that promote ecological understanding via environmental education are more likely to be successful than information-based approaches. PMID:24711965

High Frequency High Spectral Resolution Focal Plane Arrays for AtLAST

NASA Astrophysics Data System (ADS)

Baryshev, Andrey

2018-01-01

Large collecting area single dish telescope such as ATLAST will be especially effective for medium (R 1000) and high (R 50000) spectral resolution observations. Large focal plane array is a natural solution to increase mapping speed. For medium resolution direct detectors with filter banks (KIDs) and or heterodyne technology can be employed. We will analyze performance limits of comparable KID and SIS focal plane array taking into account quantum limit and high background condition of terrestrial observing site. For large heterodyne focal plane arrays, a high current density AlN junctions open possibility of large instantaneous bandwidth >40%. This and possible multi frequency band FPSs presents a practical challenge for spatial sampling and scanning strategies. We will discuss phase array feeds as a possible solution, including a modular back-end system, which can be shared between KID and SIS based FPA. Finally we will discuss achievable sensitivities and pixel co unts for a high frequency (>500 GHz) FPAs and address main technical challenges: LO distribution, wire counts, bias line multiplexing, and monolithic vs. discrete mixer component integration.

From Constructive Field Theory to Fractional Stochastic Calculus. (II) Constructive Proof of Convergence for the Lévy Area of Fractional Brownian Motion with Hurst Index {{alpha} {in} ((1)/(8),(1)/(4))}

NASA Astrophysics Data System (ADS)

Magnen, Jacques; Unterberger, Jérémie

2012-03-01

{Let $B=(B_1(t),...,B_d(t))$ be a $d$-dimensional fractional Brownian motion with Hurst index $\\alpha<1/4$, or more generally a Gaussian process whose paths have the same local regularity. Defining properly iterated integrals of $B$ is a difficult task because of the low H\\"older regularity index of its paths. Yet rough path theory shows it is the key to the construction of a stochastic calculus with respect to $B$, or to solving differential equations driven by $B$. We intend to show in a series of papers how to desingularize iterated integrals by a weak, singular non-Gaussian perturbation of the Gaussian measure defined by a limit in law procedure. Convergence is proved by using "standard" tools of constructive field theory, in particular cluster expansions and renormalization. These powerful tools allow optimal estimates, and call for an extension of Gaussian tools such as for instance the Malliavin calculus. After a first introductory paper \\cite{MagUnt1}, this one concentrates on the details of the constructive proof of convergence for second-order iterated integrals, also known as L\\'evy area.

Repeatability Evaluation of a Contrast Sensitivity System for Transfer to the Eye Clinic

NASA Astrophysics Data System (ADS)

Alcalde, N. G.; Castillo, L. R.; Filgueira, C. Paz; Colombo, E. M.

2016-04-01

The Contrast Sensitivity Function (CSF) is a valuable tool which can be used to characterize functional vision and also for the diagnosis and management of patients with different eye diseases. In spite of its usefulness, the CSF is currently hardly ever used in clinical practice. The aim of this study was to validate the use of the system called FVC-100 (Tecnovinc-UNT-CONICET, Argentina), which calculates the CSF, in order to transfer this important tool to ophthalmological clinics. The validation was carried out through the design of a repeatability test and the subsequent analysis of the results. Furthermore, we evaluated the impact of different factors influencing the repeatability of the measurements such as age and previous training. The tests were based on the discrimination of sinusoidal gratings for different spatial frequencies (1, 4 and 12 c/°) in both eyes of 12 people, aged between 20 and 70. The results show that the calculated values of SC of each subject have a high repeatability and are not dependent on age or training. These results allow us to conclude positively regarding the effectiveness of the FVC-100, and to validate its use in clinics for the calculation of the FSC as a standard measure of functional vision quality.

Ion Beam Materials Analysis and Modifications at keV to MeV Energies at the University of North Texas

NASA Astrophysics Data System (ADS)

Rout, Bibhudutta; Dhoubhadel, Mangal S.; Poudel, Prakash R.; Kummari, Venkata C.; Lakshantha, Wickramaarachchige J.; Manuel, Jack E.; Bohara, Gyanendra; Szilasi, Szabolcs Z.; Glass, Gary A.; McDaniel, Floyd D.

2014-02-01

The University of North Texas (UNT) Ion Beam Modification and Analysis Laboratory (IBMAL) has four particle accelerators including a National Electrostatics Corporation (NEC) 9SDH-2 3 MV tandem Pelletron, a NEC 9SH 3 MV single-ended Pelletron, and a 200 kV Cockcroft-Walton. A fourth HVEC AK 2.5 MV Van de Graaff accelerator is presently being refurbished as an educational training facility. These accelerators can produce and accelerate almost any ion in the periodic table at energies from a few keV to tens of MeV. They are used to modify materials by ion implantation and to analyze materials by numerous atomic and nuclear physics techniques. The NEC 9SH accelerator was recently installed in the IBMAL and subsequently upgraded with the addition of a capacitive-liner and terminal potential stabilization system to reduce ion energy spread and therefore improve spatial resolution of the probing ion beam to hundreds of nanometers. Research involves materials modification and synthesis by ion implantation for photonic, electronic, and magnetic applications, micro-fabrication by high energy (MeV) ion beam lithography, microanalysis of biomedical and semiconductor materials, development of highenergy ion nanoprobe focusing systems, and educational and outreach activities. An overview of the IBMAL facilities and some of the current research projects are discussed.

Planetary protection requirements for orbiter and netlander elements of the CNES/NASA Mars sample return mission

NASA Astrophysics Data System (ADS)

Debus, A.

In the framework of Mars exploration, particularly for missions dedicated to the search for life or for traces of ancient forms of life, NASA and CNES have decided to join their efforts in order to build a Mars sample return mission. Taking into account article IX of the OUTER SPACE TREATY (Treaty on principles governing the activities of states in the exploration and use of outer space, including the Moon and other celestial, referenced 610 UNTS 205 - resolution 2222(XXI) of December 1966, ratified in London / Washington January 27, 1967) and in order to comply with the COSPAR planetary protection recommendations, a common planetary protection program has to be established. Mars in-situ experimentations are limited by the size and the mass of the instruments necessary to perform exobiology investigations and, consequently, it appears that the best way to conduct such experiments is to bring back Mars samples to Earth. A sample return mission enables the use of a very large number of instruments and analysis protocols, giving exobiologists the best chance to find living entities or organic compounds related to life. Such a mission is complicated from a planetary protection point of view, it combines constraints for the protection of both the Mars environment as well as Earth, including the preservation of samples to ensure the validity of exobiological experiments.

Vegetation cover, avoided erosion and water quality in high Andean wetlands, Yeso River Basin

NASA Astrophysics Data System (ADS)

León, Alejandro; Soto, Jorge; Seguel, Oscar; Pérez, Javier; Osses, Daniela; Leiva, Nicolás; Zerega, Linka

2017-04-01

Wetlands on the high Andes mountains near Santiago de Chile have been impacted by overgrazing and off-road tourists. We studied wetlands in El Yeso River basin. In February 2015 we established 36 exclusions and measured vegetation cover and height, biomass production in and out the exclusions starting in October. Water and undisturbed soil samples were collected. Data were analyzed statistically to estimate i) the recovery of vegetation, and ii) the influence of grazing and vehicle traffic on vegetation loss, and iii) impacts on soil and water quality. In areas with less intense traffic, the difference in vegetation coverage in and out the exclusions is 22% (± 11.4%); in areas with more intense traffic this difference is 16% (± 16%). Height of vegetation, in the less intense traffic areas, ranges from 6.25 cm (± 2.8) to 13.32 cm (± 6.3). With higher traffic it varies between 6.9 cm (± 3.1) and 13.6 cm (± 5.4). Biomass varies between 0.06 kg DM/m2 to 0.57 kg DM/m2 depending on botanical composition and date. After water circulates through the wetlands its content of nitrogen increases 37.33% to 0.37 mg N/l and the fecal coliforms 66.67% to 0.67 MPN/100 ml, because of cattle. On the contrary, turbidity decreases 20.67% to 0.21 UNT because sediments are captured by vegetation. We also estimated an avoided erosion rate, ranging between 1.23% and 31.87% (depending on the slope) due to the increase in coverage within the exclusions.

Leucocytosis, Thrombocytosis, and Plasma Osmolality During Rest and Exercise: A Hypothesis

NASA Technical Reports Server (NTRS)

McKenzie, M. A.; Greenleaf, John E.; Looft-Wilson, R.; Barnes, P. R.

1999-01-01

The mechanism for inducing leucocytosis (increase in white blood cells) and thrombocytosis (increase in platelets) during exercise is unclear. Because plasma osmolality (Osm) may influence T-cell proliferation, Osm and the number of leucocytes (WBC) and platelets in blood were measured periodically during a 90 min rest period, and were compared with those during upright sitting ergometer exercise in six unt.rained, healthy men who cycled for 70 min at 71% of their maximal oxygen uptake (V prime O(sub 2(sub max)). There were 6 experiments in which the subjects drank different fluid formula-t4ilons (10 ml/kg) of various ionic and osmotic concentrations intermittently during 60 min of the rest period and during the exercise period. Osmolality, and WBC and platelet counts increased significantly (p<0.05) within the first 10 min of exercise, but the additional 60 min of exercise did not significantly change the leucocytosis or thrombocytosis. There were low but significant correlations between individual values of total WBC and total Osm during exercise (r(sub 0.001(2),284) = 0.39) and during rest plus exercise (r(sub 0.001(2),499) = 0.43). With combined data from the six experiments, mean Osm correlated highly and significantly with both mean WBC (r(sub 0.001(2),6) = 0.95, p < 0.001) and mean platelets (r(sub 0.001(2),6) = 0.94, p < 0.01) during the exercise phase. These data indicate that increases in leucocytes, thrombocytes, and osmolality occur primarily within the first 10 min of high-intensity exercise, but neither hypovolemia nor hyperthermia during exercise contributed to the leucocytosis, thrombocytosis, or hyperosmolality. The high correlations between plasma Osm and WBC or platelet counts suggest changes in osmolality may contribute to the mechanism of leucocytosis and thrombocytosis induced by exercise.

Peroxynitrite induces apoptosis of mouse cochlear hair cells via a Caspase-independent pathway in vitro.

PubMed

Cao, Zhixin; Yang, Qianqian; Yin, Haiyan; Qi, Qi; Li, Hongrui; Sun, Gaoying; Wang, Hongliang; Liu, Wenwen; Li, Jianfeng

2017-11-01

Peroxynitrite (ONOO - ) is a potent and versatile oxidant implicated in a number of pathophysiological processes. The present study was designed to investigate the effect of ONOO - on the cultured cochlear hair cells (HCs) of C57BL/6 mice in vitro as well as the possible mechanism underlying the action of such an oxidative stress. The in vitro primary cultured cochlear HCs were subjected to different concentrations of ONOO - , then, the cell survival and morphological changes were examined by immunofluorescence and transmission electron microscopy (TEM), the apoptosis was determined by Terminal deoxynucleotidyl transferase dUNT nick end labeling (TUNEL) assay, the mRNA expressions of Caspase-3, Caspase-8, Caspase-9, Apaf1, Bcl-2, and Bax were analyzed by RT-PCR, and the protein expressions of Caspase-3 and AIF were assessed by immunofluorescence. This work demonstrated that direct exposure of primary cultured cochlear HCs to ONOO - could result in a base-to-apex gradient injury of HCs in a concentration-dependent manner. Furthermore, ONOO - led to much more losses of outer hair cells than inner hair cells mainly through the induction of apoptosis of HCs as evidenced by TEM and TUNEL assays. The mRNA expressions of Caspase-8, Caspase-9, Apaf1, and Bax were increased and, meanwhile, the mRNA expression of Bcl-2 was decreased in response to ONOO - treatment. Of interesting, the expression of Caspase-3 had no significant change, whereas, the expression alteration of AIF was observed. These results suggested that ONOO - can effectively damage the survival of cochlear HCs via triggering the apoptotic pathway. The findings from this work suggest that ONOO - -induced apoptosis is mediated, at least in part, via a Caspase-independent pathway in cochlear HCs.

Estimation and assessment of Mars contamination.

PubMed

Debus, A

2005-01-01

Since the beginning of the exploration of Mars, more than fourty years ago, thirty-six missions have been launched, including fifty-nine different space systems such as fly-by spacecraft, orbiters, cruise modules, landing or penetrating systems. Taking into account failures at launch, about three missions out of four have been successfully sent toward the Red Planet. The fact today is that Mars orbital environment includes orbiters and perhaps debris, and that its atmosphere and its surface include terrestrial compounds and dormant microorganisms. Coming from the UN Outer Space Treaty [United Nations Treaty on Principles Governing the Activities of States in the Exploration and Use of Outer Space, including the Moon and Other Celestial Bodies (the "Outer Space Treaty") referenced 610 UNTS 205 - resolution 2222(XXI) of December 1966] and according to the COSPAR planetary protection policy recommendations [COSPAR Planetary Protection Policy (20 October 2002), accepted by the Council and Bureau, as moved for adoption by SC F and PPP, prepared by the COSPAR/IAU Workshop on Planetary Protection, 4/02 with updates 10/0, 2002], Mars environment has to be preserved so as not to jeopardize the scientific investigations, and the level of terrestrial material brought on and around Mars theoretically has to comply with this policy. It is useful to evaluate what and how many materials, compounds and microorganisms are on Mars, to list what is in orbit and to identify where all these items are. Considering assumptions about materials, spores and gas location and dispersion on Mars, average contamination levels can be estimated. It is clear now that as long as missions are sent to other extraterrestrial bodies, it is not possible to keep them perfectly clean. Mars is one of the most concerned body, and the large number of missions achieved, on-going and planned now raise the question about its possible contamination, not necessarily from a biological point of view, but with respect to all types of contamination. Answering this question, will help to assess the potential effects of such contamination on scientific results and will address concerns relative to any ethical considerations about the contamination of other planets. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

A Planetary Park system for the Moon and beyond

NASA Astrophysics Data System (ADS)

Cockell, Charles; Horneck, Gerda

Deutschland International space exploration programs foresee the establishment of human settlements on the Moon and on Mars within the next decades, following a series of robotic precursor missions. These increasing robotic visits and eventual human exploration and settlements may have an environmental impact on scientifically important sites and sites of natural beauty in the form of contamination with microorganisms and spacecraft parts, or even pollution as a consequence of in situ resource use. This concern has already been reflected in the Moon Treaty, "The Agreement Governing the Activities of States on the Moon and Other Celestial Bodies" of the United Nations, which follows the Outer Space Treaty of the UN. However, so far, the Moon Treaty has not been ratified by any nation which engages in human space programs or has plans to do so. Planetary protection guidelines as formulated by the Committee on Space Research (COSPAR) are based on the Outer Space Treaty and follow the objectives: (i) to prevent contamination by terrestrial microorganisms if this might jeopardize scientific investi-gations of possible extraterrestrial life forms, and (ii) to protect the Earth from the potential hazard posed by extraterrestrial material brought back to the Earth. As a consequence, they group exploratory missions according to the type of mission and target body in five different categories, requesting specific means of cleaning and sterilization. However, the protection of extraterrestrial environments might also encompass ethical and other non-instrumental reasons. In order to allow intense scientific research and exploitation, and on the other hand to preserve regions of the Moon for research and use by future generations, we proposed the introduction of a planetary (or lunar) park system, which would protect areas of scientific, historic and intrinsic value under a common scheme. A similar placePlaceNamePlanetary PlaceTypePark system could be established on Mars well ahead of human settlement. References: United Nations. Treaty on Principles Governing the Activities of States in the Exploration and Use of Outer Space, including the Moon and Other Celestial Bodies (the "Outer Space Treaty") referenced 610 UNTS 205 -resolution 2222(XXI) of December 1966. Cockell C.S. and Hor-neck G. (2004) A Planetary Park system for Mars. Space Policy 20, 291-295. Cockell, C.S. and PersonNameHorneck G. (2006) PlaceNameplacePlanetary PlaceTypeParks -formulating a wilderness policy for planetary bodies. Space Policy 22, 256-261.

Might astronauts one day be treated like return samples?

NASA Astrophysics Data System (ADS)

Arnould, Jacques; Debus, André

2008-09-01

The next time humans set foot on the Moon or another planet, will we treat the crew like we would a sample return mission when they come back to Earth? This may seem a surprising or even provocative question, but it is one we need to address. The hurdles and hazards of sending humans to Mars for example, the technology constraints and physiological and psychological challenges are many; but let us not forget the need to protect populations and environments from the risk of contamination [United Nations, treaty on principles governing the activities of states in the exploration and use of outer space, including the Moon and other celestial bodies (the “Outer Space Treaty”) referenced 610 UNTS 205 - resolution 2222(XXI) of December 1966]. The first hurdle is the size of crew modules. It is hard to envisage being able to decontaminate a crew module as thoroughly as we can interplanetary probes at launch. And once a crew arrives on Mars, it will not be easy either to break the chain of contact between their habitat and the Martian environment. How will astronauts avoid coming into direct contact with Mars dust when they remove their spacesuits in the airlock? How will they avoid bringing it into the crew module, and then back to Earth? At this stage, it would seem vital to do preliminary research on unmanned exobiology missions to identify zones that do not, a priori, pose a contamination hazard for astronauts. However, this precaution will not dispense with the need to perfect methods to chemically sterilize Mars dust inside airlocks, and quarantine procedures for the return to Earth. While the technology challenges of protecting astronauts and their habitat are considerable, the ethical issues are not to be underestimated either. They must be addressed alongside all the other issues bound up with human spaceflight, chief among them astronauts’ acceptance of the risk of a launch failure and other accidents, exposure to cosmic radiation and so on. For missions to another planet, it is not unreasonable to wonder whether the slightest sign of fatigue or faintness exhibited by returning astronauts might be interpreted as a possible symptom of extraterrestrial contamination. How should we handle such an eventuality? What precautions should we take? What checks should we perform? If a crew was infected, what would we do? Might they have to stay in space ad vitam aeternam if no treatment could be found? In other words, what would be the status of astronauts as both contaminated victims and vectors of contamination? How would we avoid turning such “envoys of mankind” into human guinea pigs? We do not claim to have all the answers, but we think the questions should at least be clearly aired.

Effect of surface modifications on the bond strength of zirconia ceramic with resin cement resin.

PubMed

Hallmann, Lubica; Ulmer, Peter; Lehmann, Frank; Wille, Sebastian; Polonskyi, Oleksander; Johannes, Martina; Köbel, Stefan; Trottenberg, Thomas; Bornholdt, Sven; Haase, Fabian; Kersten, Holger; Kern, Matthias

2016-05-01

Purpose of this in vitro study was to evaluate the effect of surface modifications on the tensile bond strength between zirconia ceramic and resin. Zirconia ceramic surfaces were treated with 150-μm abrasive alumina particles, 150-μm abrasive zirconia particles, argon-ion bombardment, gas plasma, and piranha solution (H2SO4:H2O2=3:1). In addition, slip casting surfaces were examined. Untreated surfaces were used as the control group. Tensile bond strengths (TBS) were measured after water storage for 3 days or 150 days with additional 37,500 thermal cycling for artificial aging. Statistical analyses were performed with 1-way and 3-way ANOVA, followed by comparison of means with the Tukey HSD test. After storage in distilled water for three days at 37 °C, the highest mean tensile bond strengths (TBS) were observed for zirconia ceramic surfaces abraded with 150-μm abrasive alumina particles (TBS(AAP)=37.3 MPa, TBS(CAAP)=40.4 MPa), and 150-μm abrasive zirconia particles (TBS(AZP)=34.8 MPa, TBS(CAZP)=35.8 MPa). Also a high TBS was observed for specimens treated with argon-ion bombardment (TBS(BAI)=37.8 MPa). After 150 days of storage, specimens abraded with 150-μm abrasive alumina particles and 150-μm abrasive zirconia particles revealed high TBS (TBS(AAP)=37.6 MPa, TBS(CAAP)=33.0 MPa, TBS(AZP)=22.1 MPa and TBS(CAZP)=22.8 MPa). A high TBS was observed also for specimens prepared with slip casting (TBS(SC)=30.0 MPa). A decrease of TBS was observed for control specimens (TBS(UNT)=12.5 MPa, TBS(CUNT)=9.0 MPa), specimens treated with argon-ion bombardment (TBS(BAI)=10.3 MPa) and gas plasma (TBS(GP)=11.0 MPa). A decrease of TBS was observed also for specimens treated with piranha solution (TBS(PS)=3.9 MPa, TBS(CPS)=4.1 MPa). A significant difference in TBS after three days storage was observed for specimens treated with different methods (p<0.001). Thermal cycling significantly reduced TBS for all groups (p<0.001) excluding groups: AAP(p>0.05), CAAP(p>0.05) and SC(p>0.05). However, the failure patterns of debonded specimens prepared with 150-μm abrasive zirconia particles were 96.7% cohesive. Treatment of zirconia ceramic surfaces with abrasive zirconia particles is a promising method to increase the tensile bond strength without significant damage of the ceramic surface itself. An alternative promising method is slip casting. Copyright © 2016 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

The member of the Academy H.P. Keres and the Relativity theory in Estonia

NASA Astrophysics Data System (ADS)

Kuusk, P.; Muursepp, P. V.; Piir, Ivar

1987-10-01

The first popular lecture on the Einstein theory of relativity was given in Estonia already in 1914 by Jaan Sarv (1877-1954)[1],afterwards a professor of mathematics at the Tartu University. The first student courses on special relativity were delivered by Professor of Mathematics Juri Nuut (1892-1952): non-Euclidean geometry (1930), the mathematical theory of relativity (1932/1933),the Lorenz transformations (1937). His own research work concerned the Lobachevsky geometry [7] and its application to cosmology [6]. Harald Keres qraguated from the Tartu University in 1936. He gave the first student course on general relativity (based on books [11-14]in 1940.In 1942,he got the dr.phil.nat degree form the Tartu University for his theses "Raum und Zeit in der allgemeinen Relativitatstheorie". The degree of the doctor of mathematical and physical sciences was confirmed by VAK (the All-Union Higher Attestation Commission) in 1949.In this period, he got aquainted with the leading Soviet scientists working on General Relativity, prof.V.A.Fock,Prof.D.D.Ivanenko,Prof.A.Z.Petrov,and Prof.M.F.Shirokov. After World War two all-union university courses were introduced in Tartu State University. According to the curriculum of the course the special theory of relativity is a part of electrodynamics obligatory for all students of the department of Physics. From 1947 till 1985 this course was delivered by Prof.PaulKard(1914-1985).He also published a number of text-books on the subject [15-19]. The general theory of relativity was read by Prof.H.Keres in 1951-1960 and later by his pupils R.Lias and A.Koppel [20-23] as a special course for students specializing in theoretical Physics. The first PHD-s in general relativity were made by R.Lias [27](1954) and I.Piir [28] (1955). In 1961, Prof.H.Keres was elected a member of the Academy of Sciences of the Estonian S.S.R. He left the TArtu State University and began to work in the Institute of Physics as the head of the Department of THeoretical Physics.His main scientific works [35-40]were made in the sixties.In his works he introduced inertial systems that can be used in the Einstein theory as well as in the Newton theory of gravitation.these systems are determined by freely falling particles and clocks and cannot be realized as a rigid frame of references. In these frames, the non-relativistic Newtonian theory can be considered as a limit of the relativistic Einstein theory. Currently the main directions of the research on general relativity in Tartu are the following: 1) connections between the relativistic and non-relativistic theories of gravitation and the corresponding exact solutions (A.Koppel), 2) radiation fields fields in a curved space-time,especially the propagation and detection of gravitational waves (I.Piir,V.Unt, R.Tamello, R.Mankin). The modern trends in theoretical physics are represented by the investigations in supergravity,curved superspace and superstrings (P.Kuusk). A detailed history of the research work on cosmology in Estonia is the subject of a subsequent paper.

Effects of the Web Behavior Change Program for Activity and Multimodal Pain Rehabilitation: Randomized Controlled Trial

PubMed Central

Michaelson, Peter; Gard, Gunvor; Eriksson, Margareta K

2016-01-01

Background Web-based interventions with a focus on behavior change have been used for pain management, but studies of Web-based interventions integrated in clinical practice are lacking. To emphasize the development of cognitive skills and behavior, and to increase activity and self-care in rehabilitation, the Web Behavior Change Program for Activity (Web-BCPA) was developed and added to multimodal pain rehabilitation (MMR). Objective The objective of our study was to evaluate the effects of MMR in combination with the Web-BCPA compared with MMR among persons with persistent musculoskeletal pain in primary health care on pain intensity, self-efficacy, and copying, as part of a larger collection of data. Web-BCPA adherence and feasibility, as well as treatment satisfaction, were also investigated. Methods A total of 109 participants, mean age 43 (SD 11) years, with persistent pain in the back, neck, shoulder, and/or generalized pain were recruited to a randomized controlled trial with two intervention arms: (1) MMR+WEB (n=60) and (2) MMR (n=49). Participants in the MMR+WEB group self-guided through the eight modules of the Web-BCPA: pain, activity, behavior, stress and thoughts, sleep and negative thoughts, communication and self-esteem, solutions, and maintenance and progress. Data were collected with a questionnaire at baseline and at 4 and 12 months. Outcome measures were pain intensity (Visual Analog Scale), self-efficacy to control pain and to control other symptoms (Arthritis Self-Efficacy Scale), general self-efficacy (General Self-Efficacy Scale), and coping (two-item Coping Strategies Questionnaire; CSQ). Web-BCPA adherence was measured as minutes spent in the program. Satisfaction and Web-BCPA feasibility were assessed by a set of items. Results Of 109 participants, 99 received the allocated intervention (MMR+WEB: n=55; MMR: n=44); 88 of 99 (82%) completed the baseline and follow-up questionnaires. Intention-to-treat analyses were performed with a sample size of 99. The MMR+WEB intervention was effective over time (time*group) compared to MMR for the two-item CSQ catastrophizing subscale (P=.003), with an effect size of 0.61 (Cohen d) at 12 months. There were no significant between-group differences over time (time*group) regarding pain intensity, self-efficacy (pain, other symptoms, and general), or regarding six subscales of the two-item CSQ. Improvements over time (time) for the whole study group were found regarding mean (P<.001) and maximum (P=.002) pain intensity. The mean time spent in the Web-based program was 304 minutes (range 0-1142). Participants rated the items of Web-BCPA feasibility between 68/100 and 90/100. Participants in the MMR+WEB group were more satisfied with their MMR at 4 months (P<.001) and at 12 months (P=.003). Conclusions Adding a self-guided Web-based intervention with a focus on behavioral change for activity to MMR can reduce catastrophizing and increase satisfaction with MMR. Patients in MMR may need more supportive coaching to increase adherence in the Web-BCPA to find it valuable. ClinicalTrial Clinicaltrials.gov NCT01475591; https://clinicaltrials.gov/ct2/show/NCT01475591 (Archived by WebCite at http://www.webcitation.org/6kUnt7VQh) PMID:27707686

Effects of the Web Behavior Change Program for Activity and Multimodal Pain Rehabilitation: Randomized Controlled Trial.

PubMed

Nordin, Catharina A; Michaelson, Peter; Gard, Gunvor; Eriksson, Margareta K

2016-10-05

Web-based interventions with a focus on behavior change have been used for pain management, but studies of Web-based interventions integrated in clinical practice are lacking. To emphasize the development of cognitive skills and behavior, and to increase activity and self-care in rehabilitation, the Web Behavior Change Program for Activity (Web-BCPA) was developed and added to multimodal pain rehabilitation (MMR). The objective of our study was to evaluate the effects of MMR in combination with the Web-BCPA compared with MMR among persons with persistent musculoskeletal pain in primary health care on pain intensity, self-efficacy, and copying, as part of a larger collection of data. Web-BCPA adherence and feasibility, as well as treatment satisfaction, were also investigated. A total of 109 participants, mean age 43 (SD 11) years, with persistent pain in the back, neck, shoulder, and/or generalized pain were recruited to a randomized controlled trial with two intervention arms: (1) MMR+WEB (n=60) and (2) MMR (n=49). Participants in the MMR+WEB group self-guided through the eight modules of the Web-BCPA: pain, activity, behavior, stress and thoughts, sleep and negative thoughts, communication and self-esteem, solutions, and maintenance and progress. Data were collected with a questionnaire at baseline and at 4 and 12 months. Outcome measures were pain intensity (Visual Analog Scale), self-efficacy to control pain and to control other symptoms (Arthritis Self-Efficacy Scale), general self-efficacy (General Self-Efficacy Scale), and coping (two-item Coping Strategies Questionnaire; CSQ). Web-BCPA adherence was measured as minutes spent in the program. Satisfaction and Web-BCPA feasibility were assessed by a set of items. Of 109 participants, 99 received the allocated intervention (MMR+WEB: n=55; MMR: n=44); 88 of 99 (82%) completed the baseline and follow-up questionnaires. Intention-to-treat analyses were performed with a sample size of 99. The MMR+WEB intervention was effective over time (time*group) compared to MMR for the two-item CSQ catastrophizing subscale (P=.003), with an effect size of 0.61 (Cohen d) at 12 months. There were no significant between-group differences over time (time*group) regarding pain intensity, self-efficacy (pain, other symptoms, and general), or regarding six subscales of the two-item CSQ. Improvements over time (time) for the whole study group were found regarding mean (P<.001) and maximum (P=.002) pain intensity. The mean time spent in the Web-based program was 304 minutes (range 0-1142). Participants rated the items of Web-BCPA feasibility between 68/100 and 90/100. Participants in the MMR+WEB group were more satisfied with their MMR at 4 months (P<.001) and at 12 months (P=.003). Adding a self-guided Web-based intervention with a focus on behavioral change for activity to MMR can reduce catastrophizing and increase satisfaction with MMR. Patients in MMR may need more supportive coaching to increase adherence in the Web-BCPA to find it valuable. Clinicaltrials.gov NCT01475591; https://clinicaltrials.gov/ct2/show/NCT01475591 (Archived by WebCite at http://www.webcitation.org/6kUnt7VQh).

Geologic map of the Yucca Mountain region, Nye County, Nevada

USGS Publications Warehouse

Potter, Christopher J.; Dickerson, Robert P.; Sweetkind, Donald S.; Drake II, Ronald M.; Taylor, Emily M.; Fridrich, Christopher J.; San Juan, Carma A.; Day, Warren C.

2002-01-01

Yucca Mountain, Nye County, Nev., has been identified as a potential site for underground storage of high-level radioactive waste. This geologic map compilation, including all of Yucca Mountain and Crater Flat, most of the Calico Hills, western Jackass Flats, Little Skull Mountain, the Striped Hills, the Skeleton Hills, and the northeastern Amargosa Desert, portrays the geologic framework for a saturated-zone hydrologic flow model of the Yucca Mountain site. Key geologic features shown on the geologic map and accompanying cross sections include: (1) exposures of Proterozoic through Devonian strata inferred to have been deformed by regional thrust faulting and folding, in the Skeleton Hills, Striped Hills, and Amargosa Desert near Big Dune; (2) folded and thrust-faulted Devonian and Mississippian strata, unconformably overlain by Miocene tuffs and lavas and cut by complex Neogene fault patterns, in the Calico Hills; (3) the Claim Canyon caldera, a segment of which is exposed north of Yucca Mountain and Crater Flat; (4) thick densely welded to nonwelded ash-flow sheets of the Miocene southwest Nevada volcanic field exposed in normal-fault-bounded blocks at Yucca Mountain; (5) upper Tertiary and Quaternary basaltic cinder cones and lava flows in Crater Flat and at southernmost Yucca Mountain; and (6) broad basins covered by Quaternary and upper Tertiary surficial deposits in Jackass Flats, Crater Flat, and the northeastern Amargosa Desert, beneath which Neogene normal and strike-slip faults are inferred to be present on the basis of geophysical data and geologic map patterns. A regional thrust belt of late Paleozoic or Mesozoic age affected all pre-Tertiary rocks in the region; main thrust faults, not exposed in the map area, are interpreted to underlie the map area in an arcuate pattern, striking north, northeast, and east. The predominant vergence of thrust faults exposed elsewhere in the region, including the Belted Range and Specter Range thrusts, was to the east, southeast, and south. The vertical to overturned strata of the Striped Hills are hypothesized to result from successive stacking of three south-vergent thrust ramps, the lowest of which is the Specter Range thrust. The CP thrust is interpreted as a north-vergent backthrust that may have been roughly contemporaneous with the Belted Range and Specter Range thrusts. The southwest Nevada volcanic field consists predominantly of a series of silicic tuffs and lava flows ranging in age from 15 to 8 Ma. The map area is in the southwestern quadrant of the southwest Nevada volcanic field, just south of the Timber Mountain caldera complex. The Claim Canyon caldera, exposed in the northern part of the map area, contains thick deposits of the 12.7-Ma Tiva Canyon Tuff, along with widespread megabreccia deposits of similar age, and subordinate thick exposures of other 12.8- to 12.7-Ma Paintbrush Group rocks. An irregular, blocky fault array, which affects parts of the caldera and much of the nearby area, includes several large-displacement, steeply dipping faults that strike radially to the caldera and bound south-dipping blocks of volcanic rock. South and southeast of the Claim Canyon caldera, in the area that includes Yucca Mountain, the Neogene fault pattern is dominated by closely spaced, north-northwest- to north-northeast-striking normal faults that lie within a north-trending graben. This 20- to 25-km-wide graben includes Crater Flat, Yucca Mountain, and Fortymile Wash, and is bounded on the east by the 'gravity fault' and on the west by the Bare Mountain fault. Both of these faults separate Proterozoic and Paleozoic sedimentary rocks in their footwalls from Miocene volcanic rocks in their hanging walls. Stratigraphic and structural relations at Yucca Mountain demonstrate that block-bounding faults were active before and during eruption of the 12.8- to 12.7-Ma Paintbrush Group, and significant motion on these faults continued unt