77 FR 16270 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft..., ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components.'' This draft LR-ISG revises...

77 FR 23513 - Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-19

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0070] Updated Aging Management Criteria for Reactor Vessel Internal Components of Pressurized Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft...-ISG), LR-ISG-2011-04, ``Updated Aging Management Criteria for PWR Reactor Vessel Internal Components...

Fluids and Combustion Facility: Fluids Integrated Rack Modal Model Correlation

NASA Technical Reports Server (NTRS)

McNelis, Mark E.; Suarez, Vicente J.; Sullivan, Timothy L.; Otten, Kim D.; Akers, James C.

2005-01-01

The Fluids Integrated Rack (FIR) is one of two racks in the Fluids and Combustion Facility on the International Space Station. The FIR is dedicated to the scientific investigation of space system fluids management supporting NASA s Exploration of Space Initiative. The FIR hardware was modal tested and FIR finite element model updated to satisfy the International Space Station model correlation criteria. The final cross-orthogonality results between the correlated model and test mode shapes was greater than 90 percent for all primary target modes.

The Cancer Family Caregiving Experience: An Updated and Expanded Conceptual Model

PubMed Central

Fletcher, Barbara Swore; Miaskowski, Christine; Given, Barbara; Schumacher, Karen

2011-01-01

Objective The decade from 2000–2010 was an era of tremendous growth in family caregiving research specific to the cancer population. This research has implications for how cancer family caregiving is conceptualized, yet the most recent comprehensive model of cancer family caregiving was published ten years ago. Our objective was to develop an updated and expanded comprehensive model of the cancer family caregiving experience, derived from concepts and variables used in research during past ten years. Methods A conceptual model was developed based on cancer family caregiving research published from 2000–2010. Results Our updated and expanded model has three main elements: 1) the stress process, 2) contextual factors, and 3) the cancer trajectory. Emerging ways of conceptualizing the relationships between and within model elements are addressed, as well as an emerging focus on caregiver-patient dyads as the unit of analysis. Conclusions Cancer family caregiving research has grown dramatically since 2000 resulting in a greatly expanded conceptual landscape. This updated and expanded model of the cancer family caregiving experience synthesizes the conceptual implications of an international body of work and demonstrates tremendous progress in how cancer family caregiving research is conceptualized. PMID:22000812

Key science issues in the central and eastern United States for the next version of the USGS National Seismic Hazard Maps

USGS Publications Warehouse

Peterson, M.D.; Mueller, C.S.

2011-01-01

The USGS National Seismic Hazard Maps are updated about every six years by incorporating newly vetted science on earthquakes and ground motions. The 2008 hazard maps for the central and eastern United States region (CEUS) were updated by using revised New Madrid and Charleston source models, an updated seismicity catalog and an estimate of magnitude uncertainties, a distribution of maximum magnitudes, and several new ground-motion prediction equations. The new models resulted in significant ground-motion changes at 5 Hz and 1 Hz spectral acceleration with 5% damping compared to the 2002 version of the hazard maps. The 2008 maps have now been incorporated into the 2009 NEHRP Recommended Provisions, the 2010 ASCE-7 Standard, and the 2012 International Building Code. The USGS is now planning the next update of the seismic hazard maps, which will be provided to the code committees in December 2013. Science issues that will be considered for introduction into the CEUS maps include: 1) updated recurrence models for New Madrid sources, including new geodetic models and magnitude estimates; 2) new earthquake sources and techniques considered in the 2010 model developed by the nuclear industry; 3) new NGA-East ground-motion models (currently under development); and 4) updated earthquake catalogs. We will hold a regional workshop in late 2011 or early 2012 to discuss these and other issues that will affect the seismic hazard evaluation in the CEUS.

NONROAD2005 Training Presentation Slides, May 2006 15th International Emission Inventory Conference (New Orleans)

EPA Pesticide Factsheets

Learn about the 2005 update to the NONROAD emissions inventory model and its features and outputs, including hands-on exercises. Keep in mind that the most current model, approved for use in SIPs, is MOVES2014a which absorbed the latest NONROAD model.

COMPILATION OF SATURATED AND UNSATURATED ZONE MODELING SOFTWARE

EPA Science Inventory

The full report provides readers an overview of available ground-water modeling programs and related software. It is an update of EPA/600/R-93/118 and EPA/600/R-94/028, two previous reports from the same program at the International Ground Water Modeling Center (IGWMC) in Colora...

The International Geomagnetic Reference Field: the twelfth generation

NASA Astrophysics Data System (ADS)

Thebault, Erwan; Finlay, Christopher; The IGRF Working Group

2015-04-01

The IGRF is an internationally-agreed reference model of the Earth's magnetic field produced under the auspices of the International Association of Geomagnetism and Aeronomy. The IGRF-12 is the latest update of this well-known model which is used each year by many thousands of users for both industrial and scientific purposes. In October 2014, ten institutions worldwide have made contributions to the IGRF. These models were evaluated and the twelfth generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2014. In this presentation, we will report on the IGRF activities, briefly describe the candidate models, summarize the evaluation of models performed by different independent teams, show how the IGRF-12 models were calculated and finally discuss some of the main magnetic features of this new model.

A State Space Model for Spatial Updating of Remembered Visual Targets during Eye Movements

PubMed Central

Mohsenzadeh, Yalda; Dash, Suryadeep; Crawford, J. Douglas

2016-01-01

In the oculomotor system, spatial updating is the ability to aim a saccade toward a remembered visual target position despite intervening eye movements. Although this has been the subject of extensive experimental investigation, there is still no unifying theoretical framework to explain the neural mechanism for this phenomenon, and how it influences visual signals in the brain. Here, we propose a unified state-space model (SSM) to account for the dynamics of spatial updating during two types of eye movement; saccades and smooth pursuit. Our proposed model is a non-linear SSM and implemented through a recurrent radial-basis-function neural network in a dual Extended Kalman filter (EKF) structure. The model parameters and internal states (remembered target position) are estimated sequentially using the EKF method. The proposed model replicates two fundamental experimental observations: continuous gaze-centered updating of visual memory-related activity during smooth pursuit, and predictive remapping of visual memory activity before and during saccades. Moreover, our model makes the new prediction that, when uncertainty of input signals is incorporated in the model, neural population activity and receptive fields expand just before and during saccades. These results suggest that visual remapping and motor updating are part of a common visuomotor mechanism, and that subjective perceptual constancy arises in part from training the visual system on motor tasks. PMID:27242452

Recommendations for kidney disease guideline updating: a report by the KDIGO Methods Committee

PubMed Central

Uhlig, Katrin; Berns, Jeffrey S.; Carville, Serena; Chan, Wiley; Cheung, Michael; Guyatt, Gordon H.; Hart, Allyson; Lewis, Sandra Zelman; Tonelli, Marcello; Webster, Angela C.; Wilt, Timothy J.; Kasiske, Bertram L.

2017-01-01

Updating rather than de novo guideline development now accounts for the majority of guideline activities for many guideline development organizations, including Kidney Disease: Improving Global Outcomes (KDIGO), an international kidney disease guideline development entity that has produced guidelines on kidney diseases since 2008. Increasingly, guideline developers are moving away from updating at fixed intervals in favor of more flexible approaches that use periodic expert assessment of guideline currency (with or without an updated systematic review) to determine the need for updating. Determining the need for guideline updating in an efficient, transparent, and timely manner is challenging, and updating of systematic reviews and guidelines is labor intensive. Ideally, guidelines should be updated dynamically when new evidence indicates a need for a substantive change in the guideline based on a priori criteria. This dynamic updating (sometimes referred to as a living guideline model) can be facilitated with the use of integrated electronic platforms that allow updating of specific recommendations. This report summarizes consensus-based recommendations from a panel of guideline methodology professionals on how to keep KDIGO guidelines up to date. PMID:26994574

Recent trends in internal medicine education: a brief update.

PubMed

Flannery, Michael T

2014-03-01

This perspective attempts to bring graduate medical offices, residency programs and medical students interested in categorical internal medicine (CIM) a brief update on the American Board of Internal Medicine (ABIM), Accreditation Council for Graduate Medical Education (ACGME) and the National Registry for Medical Programs (NRMP) changes for the past 3-5 years in the United States (US). The US model for certification and recertification may serve as a homogenous example for other countries. This model will be described so that there is an understanding of the importance of such changes in the American system and its effect on resident education. This is critical knowledge for both teachers and learners in internal medicine in preparation for a lifetime career and requirements for certification/credentialing for both programs and their residents/fellows. Data from the review indicate a small increase in the number of applicants but a concordant decrease in ABIM initial certification exams. Programs should well be aware of the new focus on outcomes via the Next Accreditation System (NAS) being put forth by the ACGME. Copyright © 2014 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

Formation of an internal model of environment dynamics during upper limb reaching movements: a fuzzy approach.

PubMed

MacDonald, Chad; Moussavi, Zahra; Sarkodie-Gyan, Thompson

2007-01-01

This paper presents the development and simulation of a fuzzy logic based learning mechanism to emulate human motor learning. In particular, fuzzy inference was used to develop an internal model of a novel dynamic environment experienced during planar reaching movements with the upper limb. A dynamic model of the human arm was developed and a fuzzy if-then rule base was created to relate trajectory movement and velocity errors to internal model update parameters. An experimental simulation was performed to compare the fuzzy system's performance with that of human subjects. It was found that the dynamic model behaved as expected, and the fuzzy learning mechanism created an internal model that was capable of opposing the environmental force field to regain a trajectory closely resembling the desired ideal.

PSI Model Curriculum for Office Careers.

ERIC Educational Resources Information Center

Professional Secretaries International, Kansas City, MO.

The PSI [Professional Secretaries International] Model Curriculum for Office Careers provides a framework for the curriculum revision process, making it easier for schools to update, change, expand, or revise their office programs. Through a series of suggested courses, this curriculum develops the knowledge, skills, and attitudes office…

Single-Trial Event-Related Potential Correlates of Belief Updating

PubMed Central

Murawski, Carsten; Bode, Stefan

2015-01-01

Abstract Belief updating—the process by which an agent alters an internal model of its environment—is a core function of the CNS. Recent theory has proposed broad principles by which belief updating might operate, but more precise details of its implementation in the human brain remain unclear. In order to address this question, we studied how two components of the human event-related potential encoded different aspects of belief updating. Participants completed a novel perceptual learning task while electroencephalography was recorded. Participants learned the mapping between the contrast of a dynamic visual stimulus and a monetary reward and updated their beliefs about a target contrast on each trial. A Bayesian computational model was formulated to estimate belief states at each trial and was used to quantify the following two variables: belief update size and belief uncertainty. Robust single-trial regression was used to assess how these model-derived variables were related to the amplitudes of the P3 and the stimulus-preceding negativity (SPN), respectively. Results showed a positive relationship between belief update size and P3 amplitude at one fronto-central electrode, and a negative relationship between SPN amplitude and belief uncertainty at a left central and a right parietal electrode. These results provide evidence that belief update size and belief uncertainty have distinct neural signatures that can be tracked in single trials in specific ERP components. This, in turn, provides evidence that the cognitive mechanisms underlying belief updating in humans can be described well within a Bayesian framework. PMID:26473170

[Purity Detection Model Update of Maize Seeds Based on Active Learning].

PubMed

Tang, Jin-ya; Huang, Min; Zhu, Qi-bing

2015-08-01

Seed purity reflects the degree of seed varieties in typical consistent characteristics, so it is great important to improve the reliability and accuracy of seed purity detection to guarantee the quality of seeds. Hyperspectral imaging can reflect the internal and external characteristics of seeds at the same time, which has been widely used in nondestructive detection of agricultural products. The essence of nondestructive detection of agricultural products using hyperspectral imaging technique is to establish the mathematical model between the spectral information and the quality of agricultural products. Since the spectral information is easily affected by the sample growth environment, the stability and generalization of model would weaken when the test samples harvested from different origin and year. Active learning algorithm was investigated to add representative samples to expand the sample space for the original model, so as to implement the rapid update of the model's ability. Random selection (RS) and Kennard-Stone algorithm (KS) were performed to compare the model update effect with active learning algorithm. The experimental results indicated that in the division of different proportion of sample set (1:1, 3:1, 4:1), the updated purity detection model for maize seeds from 2010 year which was added 40 samples selected by active learning algorithm from 2011 year increased the prediction accuracy for 2011 new samples from 47%, 33.75%, 49% to 98.89%, 98.33%, 98.33%. For the updated purity detection model of 2011 year, its prediction accuracy for 2010 new samples increased by 50.83%, 54.58%, 53.75% to 94.57%, 94.02%, 94.57% after adding 56 new samples from 2010 year. Meanwhile the effect of model updated by active learning algorithm was better than that of RS and KS. Therefore, the update for purity detection model of maize seeds is feasible by active learning algorithm.

Automatic online and real-time tumour motion monitoring during stereotactic liver treatments on a conventional linac by combined optical and sparse monoscopic imaging with kilovoltage x-rays (COSMIK)

NASA Astrophysics Data System (ADS)

Bertholet, Jenny; Toftegaard, Jakob; Hansen, Rune; Worm, Esben S.; Wan, Hanlin; Parikh, Parag J.; Weber, Britta; Høyer, Morten; Poulsen, Per R.

2018-03-01

The purpose of this study was to develop, validate and clinically demonstrate fully automatic tumour motion monitoring on a conventional linear accelerator by combined optical and sparse monoscopic imaging with kilovoltage x-rays (COSMIK). COSMIK combines auto-segmentation of implanted fiducial markers in cone-beam computed tomography (CBCT) projections and intra-treatment kV images with simultaneous streaming of an external motion signal. A pre-treatment CBCT is acquired with simultaneous recording of the motion of an external marker block on the abdomen. The 3-dimensional (3D) marker motion during the CBCT is estimated from the auto-segmented positions in the projections and used to optimize an external correlation model (ECM) of internal motion as a function of external motion. During treatment, the ECM estimates the internal motion from the external motion at 20 Hz. KV images are acquired every 3 s, auto-segmented, and used to update the ECM for baseline shifts between internal and external motion. The COSMIK method was validated using Calypso-recorded internal tumour motion with simultaneous camera-recorded external motion for 15 liver stereotactic body radiotherapy (SBRT) patients. The validation included phantom experiments and simulations hereof for 12 fractions and further simulations for 42 fractions. The simulations compared the accuracy of COSMIK with ECM-based monitoring without model updates and with model updates based on stereoscopic imaging as well as continuous kilovoltage intrafraction monitoring (KIM) at 10 Hz without an external signal. Clinical real-time tumour motion monitoring with COSMIK was performed offline for 14 liver SBRT patients (41 fractions) and online for one patient (two fractions). The mean 3D root-mean-square error for the four monitoring methods was 1.61 mm (COSMIK), 2.31 mm (ECM without updates), 1.49 mm (ECM with stereoscopic updates) and 0.75 mm (KIM). COSMIK is the first combined kV/optical real-time motion monitoring method used clinically online on a conventional accelerator. COSMIK gives less imaging dose than KIM and is in addition applicable when the kV imager cannot be deployed such as during non-coplanar fields.

WGISS-45 International Directory Network (IDN) Report

NASA Technical Reports Server (NTRS)

Morahan, Michael

2018-01-01

The objective of this presentation is to provide IDN (International Directory Network) updates on features and activities to the Committee on Earth Observation Satellites (CEOS) Working Group on Information Systems and Services (WGISS) and provider community. The following topics will be will be discussed during the presentation: Transition of Providers DIF-9 (Directory Interchange Format-9) to DIF-10 Metadata Records in the Common Metadata Repository (CMR); GCMD (Global Change Master Directory) Keyword Update; DIF-10 and UMM-C (Unified Metadata Model-Collections) Schema Changes; Metadata Validation of Provider Metadata; docBUILDER for Submitting IDN Metadata to the CMR (i.e. Registration); and Mapping WGClimate Essential Climate Variable (ECV) Inventory to IDN Records.

Towards a more transparent HTA process in Poland: new Polish HTA methodological guidelines

PubMed Central

Lach, Krzysztof; Dziwisz, Michal; Rémuzat, Cécile; Toumi, Mondher

2017-01-01

ABSTRACT Introduction: Health technology assessment (HTA) in Poland supports reimbursement decisions via the Polish HTA Agency (AOTMiT), whose guidelines were updated in 2016. Methods: We identified key changes introduced by the update and, before guideline publication, analysed discrepancies between AOTMiT assessments and the submitting marketing authorisation holders (MAHs) to elucidate the context of the update. We compared the clarity and detail of the new guidelines versus those of the UK’s National Institute for Health and Care Excellence (NICE). Results: The update specified more precise requirements for items such as indirect comparison or input data for economic modelling. Agency–MAH discrepancies relating to the subjects of the HTA update were found in 14.6% of published documents. The new Polish HTA guidelines were as clear and detailed as NICE’s on topics such as assessing quality of evidence and economic modelling, but were less informative when describing (for example) pairwise meta-analysis. Conclusions: The Polish HTA guidelines update demonstrates lessons learned from internal and external experiences. The new guidelines adhere more closely to UK HTA standards, being clearer and more informative. While the update is expected to reduce Agency–MAH discrepancies, there remain areas for development, such as providing templates to aid HTA submissions. PMID:28804603

Disruption of the Right Temporoparietal Junction Impairs Probabilistic Belief Updating.

PubMed

Mengotti, Paola; Dombert, Pascasie L; Fink, Gereon R; Vossel, Simone

2017-05-31

Generating and updating probabilistic models of the environment is a fundamental modus operandi of the human brain. Although crucial for various cognitive functions, the neural mechanisms of these inference processes remain to be elucidated. Here, we show the causal involvement of the right temporoparietal junction (rTPJ) in updating probabilistic beliefs and we provide new insights into the chronometry of the process by combining online transcranial magnetic stimulation (TMS) with computational modeling of behavioral responses. Female and male participants performed a modified location-cueing paradigm, where false information about the percentage of cue validity (%CV) was provided in half of the experimental blocks to prompt updating of prior expectations. Online double-pulse TMS over rTPJ 300 ms (but not 50 ms) after target appearance selectively decreased participants' updating of false prior beliefs concerning %CV, reflected in a decreased learning rate of a Rescorla-Wagner model. Online TMS over rTPJ also impacted on participants' explicit beliefs, causing them to overestimate %CV. These results confirm the involvement of rTPJ in updating of probabilistic beliefs, thereby advancing our understanding of this area's function during cognitive processing. SIGNIFICANCE STATEMENT Contemporary views propose that the brain maintains probabilistic models of the world to minimize surprise about sensory inputs. Here, we provide evidence that the right temporoparietal junction (rTPJ) is causally involved in this process. Because neuroimaging has suggested that rTPJ is implicated in divergent cognitive domains, the demonstration of an involvement in updating internal models provides a novel unifying explanation for these findings. We used computational modeling to characterize how participants change their beliefs after new observations. By interfering with rTPJ activity through online transcranial magnetic stimulation, we showed that participants were less able to update prior beliefs with TMS delivered at 300 ms after target onset. Copyright © 2017 the authors 0270-6474/17/375419-10$15.00/0.

Gating based on internal/external signals with dynamic correlation updates.

PubMed

Wu, Huanmei; Zhao, Qingya; Berbeco, Ross I; Nishioka, Seiko; Shirato, Hiroki; Jiang, Steve B

2008-12-21

Precise localization of mobile tumor positions in real time is critical to the success of gated radiotherapy. Tumor positions are usually derived from either internal or external surrogates. Fluoroscopic gating based on internal surrogates, such as implanted fiducial markers, is accurate however requiring a large amount of imaging dose. Gating based on external surrogates, such as patient abdominal surface motion, is non-invasive however less accurate due to the uncertainty in the correlation between tumor location and external surrogates. To address these complications, we propose to investigate an approach based on hybrid gating with dynamic internal/external correlation updates. In this approach, the external signal is acquired at high frequency (such as 30 Hz) while the internal signal is sparsely acquired (such as 0.5 Hz or less). The internal signal is used to validate and update the internal/external correlation during treatment. Tumor positions are derived from the external signal based on the newly updated correlation. Two dynamic correlation updating algorithms are introduced. One is based on the motion amplitude and the other is based on the motion phase. Nine patients with synchronized internal/external motion signals are simulated retrospectively to evaluate the effectiveness of hybrid gating. The influences of different clinical conditions on hybrid gating, such as the size of gating windows, the optimal timing for internal signal acquisition and the acquisition frequency are investigated. The results demonstrate that dynamically updating the internal/external correlation in or around the gating window will reduce false positive with relatively diminished treatment efficiency. This improvement will benefit patients with mobile tumors, especially greater for early stage lung cancers, for which the tumors are less attached or freely floating in the lung.

“AQMEII Status Update”

EPA Science Inventory

“AQMEII Status Update”This presentation provided an overview and status update of the Air Quality Model Evaluation International Initative (AQMEII) to participants of a workshop of the Task Force on Hemispheric Transport of Air Pollution (TF-HTAP) . In addition, the p...

International Space Station (ISS) Plasma Contactor Unit (PCU) Utilization Plan Assessment Update

NASA Technical Reports Server (NTRS)

Hernandez-Pellerano, Amri; Iannello, Christopher J.; Wollack, Edward J.; Wright, Kenneth H.; Garrett, Henry B.; Ging, Andrew T.; Katz, Ira; Keith, R. Lloyd; Minow, Joseph I.; Willis, Emily M.;

Application of tissue time course data to elucidate mechanistic details of carbon tetrachloride (CC14) transport using an updated physiologically based pharmacokinetic (PBPK) model in rats

EPA Science Inventory

CCl4 is a common environmental contaminant in water and superfund sites, and a model liver toxicant. One application of PBPK models used in risk assessment is simulation of internal dose for the metric involved with toxicity, particularly for different routes of exposure. Time-co...

Updates to building-code maps for the 2015 NEHRP recommended seismic provisions

USGS Publications Warehouse

Luco, Nicolas; Bachman, Robert; Crouse, C.B; Harris, James R.; Hooper, John D.; Kircher, Charles A.; Caldwell, Phillp; Rukstales, Kenneth S.

2015-01-01

With the 2014 update of the U.S. Geological Survey (USGS) National Seismic Hazard Model (NSHM) as a basis, the Building Seismic Safety Council (BSSC) has updated the earthquake ground motion maps in the National Earthquake Hazards Reduction Program (NEHRP) Recommended Seismic Provisions for New Buildings and Other Structures, with partial funding from the Federal Emergency Management Agency. Anticipated adoption of the updated maps into the American Society of Civil Engineers Minimum Design Loads for Building and Other Structures and the International Building and Residential Codes is underway. Relative to the ground motions in the prior edition of each of these documents, most of the updated values are within a ±20% change. The larger changes are, in most cases, due to the USGS NSHM updates, reasons for which are given in companion publications. In some cases, the larger changes are partly due to a BSSC update of the slope of the fragility curve that is used to calculate the risk-targeted ground motions, and/or the introduction by BSSC of a quantitative definition of “active faults” used to calculate deterministic ground motions.

Use of distributed snow cover information to update snow storages of a lumped rainfall-runoff model operationally

NASA Astrophysics Data System (ADS)

Lisniak, D.; Meissner, D.; Klein, B.; Pinzinger, R.

2013-12-01

The German Federal Institute of Hydrology (BfG) offers navigational water-level forecasting services on the Federal Waterways, like the rivers Rhine and Danube. In cooperation with the Federal States this mandate also includes the forecasting of flood events. For the River Rhine, the most frequented inland waterway in Central Europe, the BfG employs a hydrological model (HBV) coupled to a hydraulic model (SOBEK) by the FEWS-framework to perform daily forecasts of water-levels operationally. Sensitivity studies have shown that the state of soil water storage in the hydrological model is a major factor of uncertainty when performing short- to medium-range forecasts some days ahead. Taking into account the various additional sources of uncertainty associated with hydrological modeling, including measurement uncertainties, it is essential to estimate an optimal initial state of the soil water storage before propagating it in time, forced by meteorological forecasts, and transforming it into discharge. We show, that using the Ensemble Kalman Filter these initial states can be updated straightforward under certain hydrologic conditions. However, this approach is not sufficient if the runoff is mainly generated by snow melt. Since the snow cover evolution is modeled rather poorly by the HBV-model in our operational setting, flood events caused by snow melt are consistently underestimated by the HBV-model, which has long term effects in basins characterized by a nival runoff regime. Thus, it appears beneficial to update the snow storage of the HBV-model with information derived from regionalized snow cover observations. We present a method to incorporate spatially distributed snow cover observations into the lumped HBV-model. We show the plausibility of this approach and asses the benefits of a coupled snow cover and soil water storage updating, which combine a direct insertion with an Ensemble Kalman Filter. The Ensemble Kalman Filter used here takes into account the internal routing mechanism of the HBV-model, which causes a delayed response of the simulated discharge at the catchment outlet to changes in internal states.

Path integration of head direction: updating a packet of neural activity at the correct speed using neuronal time constants.

PubMed

Walters, D M; Stringer, S M

2010-07-01

A key question in understanding the neural basis of path integration is how individual, spatially responsive, neurons may self-organize into networks that can, through learning, integrate velocity signals to update a continuous representation of location within an environment. It is of vital importance that this internal representation of position is updated at the correct speed, and in real time, to accurately reflect the motion of the animal. In this article, we present a biologically plausible model of velocity path integration of head direction that can solve this problem using neuronal time constants to effect natural time delays, over which associations can be learned through associative Hebbian learning rules. The model comprises a linked continuous attractor network and competitive network. In simulation, we show that the same model is able to learn two different speeds of rotation when implemented with two different values for the time constant, and without the need to alter any other model parameters. The proposed model could be extended to path integration of place in the environment, and path integration of spatial view.

International Update; November 1990-October 1991.

ERIC Educational Resources Information Center

Tokuyama, M. Yukie, Ed.; Walden, Shauna, Ed.

1991-01-01

"International Update" is a newsletter providing information on two-year college international education activities and on funding opportunities and governmental/legislative trends that will affect community and junior colleges' ability to expand their efforts in such areas as services for foreign students, bilingual education, and study abroad…

75 FR 5351 - Proposed Revisions to Accounting Guide for LSC Recipients

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... elements of an adequate accounting and financial reporting system, including the use of specific internal... checklist of accounting procedures and internal controls. The proposed revisions update the checklist to... accounting procedures and internal controls to reflect current best practices; (7) updated and new references...

The updating of clinical practice guidelines: insights from an international survey

PubMed Central

2011-01-01

Background Clinical practice guidelines (CPGs) have become increasingly popular, and the methodology to develop guidelines has evolved enormously. However, little attention has been given to the updating process, in contrast to the appraisal of the available literature. We conducted an international survey to identify current practices in CPG updating and explored the need to standardize and improve the methods. Methods We developed a questionnaire (28 items) based on a review of the existing literature about guideline updating and expert comments. We carried out the survey between March and July 2009, and it was sent by email to 106 institutions: 69 members of the Guidelines International Network who declared that they developed CPGs; 30 institutions included in the U.S. National Guideline Clearinghouse database that published more than 20 CPGs; and 7 institutions selected by an expert committee. Results Forty-four institutions answered the questionnaire (42% response rate). In the final analysis, 39 completed questionnaires were included. Thirty-six institutions (92%) reported that they update their guidelines. Thirty-one institutions (86%) have a formal procedure for updating their guidelines, and 19 (53%) have a formal procedure for deciding when a guideline becomes out of date. Institutions describe the process as moderately rigorous (36%) or acknowledge that it could certainly be more rigorous (36%). Twenty-two institutions (61%) alert guideline users on their website when a guideline is older than three to five years or when there is a risk of being outdated. Twenty-five institutions (64%) support the concept of "living guidelines," which are continuously monitored and updated. Eighteen institutions (46%) have plans to design a protocol to improve their guideline-updating process, and 21 (54%) are willing to share resources with other organizations. Conclusions Our study is the first to describe the process of updating CPGs among prominent guideline institutions across the world, providing a comprehensive picture of guideline updating. There is an urgent need to develop rigorous international standards for this process and to minimize duplication of effort internationally. PMID:21914177

Full Gradient Solution to Adaptive Hybrid Control

NASA Technical Reports Server (NTRS)

Bean, Jacob; Schiller, Noah H.; Fuller, Chris

2017-01-01

This paper focuses on the adaptation mechanisms in adaptive hybrid controllers. Most adaptive hybrid controllers update two filters individually according to the filtered reference least mean squares (FxLMS) algorithm. Because this algorithm was derived for feedforward control, it does not take into account the presence of a feedback loop in the gradient calculation. This paper provides a derivation of the proper weight vector gradient for hybrid (or feedback) controllers that takes into account the presence of feedback. In this formulation, a single weight vector is updated rather than two individually. An internal model structure is assumed for the feedback part of the controller. The full gradient is equivalent to that used in the standard FxLMS algorithm with the addition of a recursive term that is a function of the modeling error. Some simulations are provided to highlight the advantages of using the full gradient in the weight vector update rather than the approximation.

Full Gradient Solution to Adaptive Hybrid Control

NASA Technical Reports Server (NTRS)

Bean, Jacob; Schiller, Noah H.; Fuller, Chris

2016-01-01

This paper focuses on the adaptation mechanisms in adaptive hybrid controllers. Most adaptive hybrid controllers update two filters individually according to the filtered-reference least mean squares (FxLMS) algorithm. Because this algorithm was derived for feedforward control, it does not take into account the presence of a feedback loop in the gradient calculation. This paper provides a derivation of the proper weight vector gradient for hybrid (or feedback) controllers that takes into account the presence of feedback. In this formulation, a single weight vector is updated rather than two individually. An internal model structure is assumed for the feedback part of the controller. The full gradient is equivalent to that used in the standard FxLMS algorithm with the addition of a recursive term that is a function of the modeling error. Some simulations are provided to highlight the advantages of using the full gradient in the weight vector update rather than the approximation.

Primary Immunodeficiency Diseases: An Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency

PubMed Central

Al-Herz, Waleed; Bousfiha, Aziz; Casanova, Jean-Laurent; Chapel, Helen; Conley, Mary Ellen; Cunningham-Rundles, Charlotte; Etzioni, Amos; Fischer, Alain; Franco, Jose Luis; Geha, Raif S.; Hammarström, Lennart; Nonoyama, Shigeaki; Notarangelo, Luigi Daniele; Ochs, Hans Dieter; Puck, Jennifer M.; Roifman, Chaim M.; Seger, Reinhard; Tang, Mimi L. K.

2011-01-01

We report the updated classification of primary immunodeficiency diseases, compiled by the ad hoc Expert Committee of the International Union of Immunological Societies. As compared to the previous edition, more than 15 novel disease entities have been added in the updated version. For each disorders, the key clinical and laboratory features are provided. This updated classification is meant to help in the diagnostic approach to patients with these diseases. PMID:22566844

International river basins of the world

USGS Publications Warehouse

Wolf, Aaron T.; Natharius, Jeffrey A.; Danielson, Jeffrey J.; Ward, Brian S.; Pender, Jan K.

1999-01-01

It is becoming acknowledged that water is likely to be the most pressing environmental concern of the next century. Difficulties in river basin management are only exacerbated when the resource crosses international boundaries. One critical aid in the assessment of international waters has been the Register of International Rivers a compendium which listed 214 international waterways that cover 47% of the earth's continental land surface. The Register, though, was last updated in 1978 by the now defunct United Nations Department of Economic and Social Affairs. The purpose of this paper is to update the Register in order to reflect the quantum changes that have taken place over the last 22 years, both in global geopolitics and in map coverage and technology. By accessing digital elevation models at spatial resolutions of 30 arc seconds, corroborating at a unified global map coverage of at least 1:1 000 000, and superimposing the results over complete coverage of current political boundaries, we are able to provide a new register which lists 261 international rivers, covering 45.3% of the land surface of the earth (excluding Antarctica). This paper lists all international rivers with their watershed areas, the nations which share each watershed,their respective territorial percentages, and notes on changes in or disputes over international boundaries since 1978.

Teaching International Public Relations: An Update Report among Educators

ERIC Educational Resources Information Center

Mak, Angela Ka Ying

2017-01-01

Involvement in international and multicultural career-related practices is ever on the rise in a global economic and political society, especially in public relations. This article reported an update of examining the attributes of public relations educators and their institutions in teaching of international public relations (IPR) through an…

75 FR 17699 - Quarterly Update to Annual Listing of Foreign Government Subsidies on Articles of Cheese Subject...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-07

... DEPARTMENT OF COMMERCE International Trade Administration Quarterly Update to Annual Listing of... Administration, International Trade Administration, Department of Commerce. EFFECTIVE DATE: April 7, 2010. FOR..., International Trade Administration, U.S. Department of Commerce, 14th Street and Constitution Ave., NW...

76 FR 60805 - Quarterly Update to Annual Listing of Foreign Government Subsidies on Articles of Cheese Subject...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... DEPARTMENT OF COMMERCE International Trade Administration Quarterly Update to Annual Listing of... Administration, International Trade Administration, Department of Commerce. DATES: Effective Date: September 30... Administration, International Trade Administration, U.S. Department of Commerce, 14th Street and Constitution Ave...

Analysis of geomagnetic secular variation during 1980-1985 and 1985- 1990, and geomagnetic models proposed for the 1991 revision of the International Geomagnetic Reference Field

USGS Publications Warehouse

Peddie, N.W.

1992-01-01

The secular variation of the main geomagnetic field during the periods 1980-1985 and 1985-1990 was analyzed in terms of spherical harmonics up to the eighth degree and order. Data from worldwide magnetic observatories and the Navy's Project MAGNET aerial surveys were used. The resulting pair of secular-variation models was used to update the Definitive Geomagnetic Reference Field (DGRF) model for 1980, resulting in new mainfield models for 1985.0 and 1990.0. These, along with the secular-variation model for 1985-1990, were proposed for the 1991 revision of the International Geomagnetic Reference Field (IGRF). -Author

Building a Better Campus: An Update on Building Codes.

ERIC Educational Resources Information Center

Madden, Michael J.

2002-01-01

Discusses the implications for higher education institutions in terms of facility planning, design, construction, and renovation of the move from regionally-developed model-building codes to two international sets of codes. Also addresses the new performance-based design option within the codes. (EV)

Updating of states in operational hydrological models

NASA Astrophysics Data System (ADS)

Bruland, O.; Kolberg, S.; Engeland, K.; Gragne, A. S.; Liston, G.; Sand, K.; Tøfte, L.; Alfredsen, K.

2012-04-01

Operationally the main purpose of hydrological models is to provide runoff forecasts. The quality of the model state and the accuracy of the weather forecast together with the model quality define the runoff forecast quality. Input and model errors accumulate over time and may leave the model in a poor state. Usually model states can be related to observable conditions in the catchment. Updating of these states, knowing their relation to observable catchment conditions, influence directly the forecast quality. Norway is internationally in the forefront in hydropower scheduling both on short and long terms. The inflow forecasts are fundamental to this scheduling. Their quality directly influence the producers profit as they optimize hydropower production to market demand and at the same time minimize spill of water and maximize available hydraulic head. The quality of the inflow forecasts strongly depends on the quality of the models applied and the quality of the information they use. In this project the focus has been to improve the quality of the model states which the forecast is based upon. Runoff and snow storage are two observable quantities that reflect the model state and are used in this project for updating. Generally the methods used can be divided in three groups: The first re-estimates the forcing data in the updating period; the second alters the weights in the forecast ensemble; and the third directly changes the model states. The uncertainty related to the forcing data through the updating period is due to both uncertainty in the actual observation and to how well the gauging stations represent the catchment both in respect to temperatures and precipitation. The project looks at methodologies that automatically re-estimates the forcing data and tests the result against observed response. Model uncertainty is reflected in a joint distribution of model parameters estimated using the Dream algorithm.

Experimental liver fibrosis research: update on animal models, legal issues and translational aspects

PubMed Central

2013-01-01

Liver fibrosis is defined as excessive extracellular matrix deposition and is based on complex interactions between matrix-producing hepatic stellate cells and an abundance of liver-resident and infiltrating cells. Investigation of these processes requires in vitro and in vivo experimental work in animals. However, the use of animals in translational research will be increasingly challenged, at least in countries of the European Union, because of the adoption of new animal welfare rules in 2013. These rules will create an urgent need for optimized standard operating procedures regarding animal experimentation and improved international communication in the liver fibrosis community. This review gives an update on current animal models, techniques and underlying pathomechanisms with the aim of fostering a critical discussion of the limitations and potential of up-to-date animal experimentation. We discuss potential complications in experimental liver fibrosis and provide examples of how the findings of studies in which these models are used can be translated to human disease and therapy. In this review, we want to motivate the international community to design more standardized animal models which might help to address the legally requested replacement, refinement and reduction of animals in fibrosis research. PMID:24274743

Bio-fuels energy policy and grain transportation flows : implications for inland waterways and short sea shipping.

DOT National Transportation Integrated Search

2010-09-15

This project develops a foundation for analysis of the effects of U.S. biofuel energy policy on domestic : and international grain flows and patterns. The primary deliverable of this project is an updated and : expanded spatial equilibrium model of w...

AceTree: a major update and case study in the long term maintenance of open-source scientific software.

PubMed

Katzman, Braden; Tang, Doris; Santella, Anthony; Bao, Zhirong

2018-04-04

AceTree, a software application first released in 2006, facilitates exploration, curation and editing of tracked C. elegans nuclei in 4-dimensional (4D) fluorescence microscopy datasets. Since its initial release, AceTree has been continuously used to interact with, edit and interpret C. elegans lineage data. In its 11 year lifetime, AceTree has been periodically updated to meet the technical and research demands of its community of users. This paper presents the newest iteration of AceTree which contains extensive updates, demonstrates the new applicability of AceTree in other developmental contexts, and presents its evolutionary software development paradigm as a viable model for maintaining scientific software. Large scale updates have been made to the user interface for an improved user experience. Tools have been grouped according to functionality and obsolete methods have been removed. Internal requirements have been changed that enable greater flexibility of use both in C. elegans contexts and in other model organisms. Additionally, the original 3-dimensional (3D) viewing window has been completely reimplemented. The new window provides a new suite of tools for data exploration. By responding to technical advancements and research demands, AceTree has remained a useful tool for scientific research for over a decade. The updates made to the codebase have extended AceTree's applicability beyond its initial use in C. elegans and enabled its usage with other model organisms. The evolution of AceTree demonstrates a viable model for maintaining scientific software over long periods of time.

A Meteorological Model's Dependence on Radiation Update Frequency

NASA Technical Reports Server (NTRS)

Eastman, Joseph L.; Peters-Lidard, Christa; Tao, Wei-Kuo; Kumar, Sujay; Tian, Yudong; Lang, Stephen E.; Zeng, Xiping

2004-01-01

Numerical weather models are used to simulate circulations in the atmosphere including clouds and precipitation by applying a set of mathematical equations over a three-dimensional grid. The grid is composed of discrete points at which the meteorological variables are defined. As computing power continues to rise these models are being used at finer grid spacing, but they must still cover a wide range of scales. Some of the physics that must be accounted for in the model cannot be explicitly resolved, and their effects, therefore, must be estimated or "parameterized". Some of these parameterizations are computationally expensive. To alleviate the problem, they are not always updated at the time resolution of the model with the assumption being that the impact will be small. In this study, a coupled land-atmosphere model is used to assess the impact of less frequent updates of the computationally expensive radiation physics for a case on June 6, 2002, that occurred during a field experiment over the central plains known as International H20 Project (IHOP). The model was tested using both the original conditions, which were dry, and with modified conditions wherein moisture was added to the lower part of the atmosphere to produce clouds and precipitation (i.e., a wet case). For each of the conditions (i.e., dry and wet), four set of experiments were conducted wherein the model was run for a period of 24 hours and the radiation fields (including both incoming solar and outgoing longwave) were updated every 1, 3, 10, and 100 time steps. Statistical tests indicated that average quantities of surface variables for both the dry and wet cases were the same for the various update frequencies. However, spatially the results could be quite different especially in the wet case after it began to rain. The near-surface wind field was found to be different most of the time even for the dry case. In the wet case, rain intensities and average vertical profiles of heating associated with cloudy areas were found to differ for the various radiation update frequencies. The latter implies that the mean state of the model could be different as a result of not updating the radiation fields every time step and has important implications for longer term climate studies

Ares I-X First Stage Internal Aft Skirt Re-Entry Heating Data and Modeling

NASA Technical Reports Server (NTRS)

Schmitz, Craig P.; Tashakkor, Scott B.

2011-01-01

The CLVSTATE engineering code is being used to predict Ares-I launch vehicle first stage reentry aerodynamic heating. An engineering analysis is developed which yields reasonable predictions for the timing of the first stage aft skirt thermal curtain failure and the resulting internal gas temperatures. The analysis is based on correlations of the Ares I-X internal aft skirt gas temperatures and has been implemented into CLVSTATE. Validation of the thermal curtain opening models has been accomplished using additional Ares I-X thermocouple, calorimeter and pressure flight data. In addition, a technique which accounts for radiation losses at high altitudes has been developed which improves the gas temperature measurements obtained by the gas temperature probes (GTP). Updates to the CLVSTATE models are shown to improve the accuracy of the internal aft skirt heating predictions which will result in increased confidence in future vehicle designs

ISO Standards Update

EPA Science Inventory

This presentation provides a brief update on activities of ISO (International Organization for Standardization) TC (Technical Committee) 285, Clean Cooking Solutions. Slides include information on: (1) Working Group project status updates, (2) background on laboratory and field ...

48 CFR 52.216-7 - Allowable Cost and Payment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... last disclosure of internal audit reports to the Government. (J) Annual internal audit plan of...-contract cost allowability limitations, and billing limitations. (v) The Contractor shall update the billings on all contracts to reflect the final settled rates and update the schedule of cumulative direct...

Effective Solar Indices for Ionospheric Modeling: A Review and a Proposal for a Real-Time Regional IRI

NASA Astrophysics Data System (ADS)

Pignalberi, A.; Pezzopane, M.; Rizzi, R.; Galkin, I.

2018-01-01

The first part of this paper reviews methods using effective solar indices to update a background ionospheric model focusing on those employing the Kriging method to perform the spatial interpolation. Then, it proposes a method to update the International Reference Ionosphere (IRI) model through the assimilation of data collected by a European ionosonde network. The method, called International Reference Ionosphere UPdate (IRI UP), that can potentially operate in real time, is mathematically described and validated for the period 9-25 March 2015 (a time window including the well-known St. Patrick storm occurred on 17 March), using IRI and IRI Real Time Assimilative Model (IRTAM) models as the reference. It relies on foF2 and M(3000)F2 ionospheric characteristics, recorded routinely by a network of 12 European ionosonde stations, which are used to calculate for each station effective values of IRI indices IG_{12} and R_{12} (identified as IG_{{12{eff}}} and R_{{12{eff}}}); then, starting from this discrete dataset of values, two-dimensional (2D) maps of IG_{{12{eff}}} and R_{{12{eff}}} are generated through the universal Kriging method. Five variogram models are proposed and tested statistically to select the best performer for each effective index. Then, computed maps of IG_{{12{eff}}} and R_{{12{eff}}} are used in the IRI model to synthesize updated values of foF2 and hmF2. To evaluate the ability of the proposed method to reproduce rapid local changes that are common under disturbed conditions, quality metrics are calculated for two test stations whose measurements were not assimilated in IRI UP, Fairford (51.7°N, 1.5°W) and San Vito (40.6°N, 17.8°E), for IRI, IRI UP, and IRTAM models. The proposed method turns out to be very effective under highly disturbed conditions, with significant improvements of the foF2 representation and noticeable improvements of the hmF2 one. Important improvements have been verified also for quiet and moderately disturbed conditions. A visual analysis of foF2 and hmF2 maps highlights the ability of the IRI UP method to catch small-scale changes occurring under disturbed conditions which are not seen by IRI.

An Enrollment Marketing Plan for Institutions of Higher Learning: An Update.

ERIC Educational Resources Information Center

Bingham, Frank G., Jr.

1996-01-01

A college marketing model consisting of several strategies and contingency plans for decision-making under difficult conditions is outlined. The plan provides for orderly transition from one marketing stage to the next logical stage, allowing some control over both internal and external environments, and providing insight into the delicate…

Recent Updates to the MELCOR 1.8.2 Code for ITER Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Merrill, Brad J

This report documents recent changes made to the MELCOR 1.8.2 computer code for application to the International Thermonuclear Experimental Reactor (ITER), as required by ITER Task Agreement ITA 81-18. There are four areas of change documented by this report. The first area is the addition to this code of a model for transporting HTO. The second area is the updating of the material oxidation correlations to match those specified in the ITER Safety Analysis Data List (SADL). The third area replaces a modification to an aerosol tranpsort subroutine that specified the nominal aerosol density internally with one that now allowsmore » the user to specify this density through user input. The fourth area corrected an error that existed in an air condensation subroutine of previous versions of this modified MELCOR code. The appendices of this report contain FORTRAN listings of the coding for these modifications.« less

INTERNATIONAL REPORT: Practical realization of the definition of the metre, including recommended radiations of other optical frequency standards (2003)

NASA Astrophysics Data System (ADS)

Felder, R.

2005-08-01

In 2003, the International Committee for Weights and Measures (CIPM) recommended updated values of the frequency for certain optical frequency standards recommended for the practical realization of the definition of the metre. The text of this CIPM Recommendation and details of the updated radiations are given here. The complete updated set of recommended radiations, including frequencies, wavelengths, uncertainties and operating conditions where appropriate, is available on the BIPM website.

75 FR 79293 - Amendment and Revocation of Class E Airspace; Vero Beach, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-20

... geographic coordinates of the St. Lucie County International Airport to aid in the navigation of our National... the National Aeronautical Navigation Services to update the geographic coordinates of the St. Lucie.... Also, this action will update the geographic coordinates of the St. Lucie County International Airport...

WHO Expert Committee on Specifications for Pharmaceutical Preparations.

PubMed

2014-01-01

The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear, independent and practical standards and guidelines for the quality assurance of medicines. Standards are developed by the Committee through worldwide consultation and an international consensus-building process. The following new guidelines were adopted and recommended for use, in addition to 20 monographs and general texts for inclusion in The International Pharmacopoeia and 11 new International Chemical Reference Substances. The International Pharmacopoeia--updating mechanism for the section on radiopharmaceuticals; WHO good manufacturing practices for pharmaceutical products: main principles; Model quality assurance system for procurement agencies; Assessment tool based on the model quality assurance system for procurement agencies: aide-memoire for inspection; Guidelines on submission of documentation for prequalification of finished pharmaceutical products approved by stringent regulatory authorities; and Guidelines on submission of documentation for a multisource (generic) finished pharmaceutical product: quality part.

Adaptive System Modeling for Spacecraft Simulation

NASA Technical Reports Server (NTRS)

Thomas, Justin

2011-01-01

This invention introduces a methodology and associated software tools for automatically learning spacecraft system models without any assumptions regarding system behavior. Data stream mining techniques were used to learn models for critical portions of the International Space Station (ISS) Electrical Power System (EPS). Evaluation on historical ISS telemetry data shows that adaptive system modeling reduces simulation error anywhere from 50 to 90 percent over existing approaches. The purpose of the methodology is to outline how someone can create accurate system models from sensor (telemetry) data. The purpose of the software is to support the methodology. The software provides analysis tools to design the adaptive models. The software also provides the algorithms to initially build system models and continuously update them from the latest streaming sensor data. The main strengths are as follows: Creates accurate spacecraft system models without in-depth system knowledge or any assumptions about system behavior. Automatically updates/calibrates system models using the latest streaming sensor data. Creates device specific models that capture the exact behavior of devices of the same type. Adapts to evolving systems. Can reduce computational complexity (faster simulations).

Notification: FY 2017 Update of Proposed Key Management Challenges and Internal Control Weaknesses Confronting the U.S. Chemical Safety and Hazard Investigation Board

EPA Pesticide Factsheets

Jan 5, 2017. The EPA OIG is beginning work to update for fiscal year 2017 its list of proposed key management challenges and internal control weaknesses confronting the U.S. Chemical Safety and Hazard Investigation Board (CSB).

ISS Ambient Air Quality: Updated Inventory of Known Aerosol Sources

NASA Technical Reports Server (NTRS)

Meyer, Marit

2014-01-01

Spacecraft cabin air quality is of fundamental importance to crew health, with concerns encompassing both gaseous contaminants and particulate matter. Little opportunity exists for direct measurement of aerosol concentrations on the International Space Station (ISS), however, an aerosol source model was developed for the purpose of filtration and ventilation systems design. This model has successfully been applied, however, since the initial effort, an increase in the number of crewmembers from 3 to 6 and new processes on board the ISS necessitate an updated aerosol inventory to accurately reflect the current ambient aerosol conditions. Results from recent analyses of dust samples from ISS, combined with a literature review provide new predicted aerosol emission rates in terms of size-segregated mass and number concentration. Some new aerosol sources have been considered and added to the existing array of materials. The goal of this work is to provide updated filtration model inputs which can verify that the current ISS filtration system is adequate and filter lifetime targets are met. This inventory of aerosol sources is applicable to other spacecraft, and becomes more important as NASA considers future long term exploration missions, which will preclude the opportunity for resupply of filtration products.

NREL: International Activities - U.S.-China Renewable Energy Partnership

Science.gov Websites

Solar PV and TC88 Wind working groups. Renewable Energy Technology These projects enhance policies to Collaboration on innovative business models and financing solutions for solar PV deployment. Micrositing and O development. Current Projects Recommendations for photovoltaic (PV) and wind grid code updates. New energy

Internal models and prediction of visual gravitational motion.

PubMed

Zago, Myrka; McIntyre, Joseph; Senot, Patrice; Lacquaniti, Francesco

2008-06-01

Baurès et al. [Baurès, R., Benguigui, N., Amorim, M.-A., & Siegler, I. A. (2007). Intercepting free falling objects: Better use Occam's razor than internalize Newton's law. Vision Research, 47, 2982-2991] rejected the hypothesis that free-falling objects are intercepted using a predictive model of gravity. They argued instead for "a continuous guide for action timing" based on visual information updated till target capture. Here we show that their arguments are flawed, because they fail to consider the impact of sensori-motor delays on interception behaviour and the need for neural compensation of such delays. When intercepting a free-falling object, the delays can be overcome by a predictive model of the effects of gravity on target motion.

A heuristic mathematical model for the dynamics of sensory conflict and motion sickness

NASA Technical Reports Server (NTRS)

Oman, C. M.

1982-01-01

By consideration of the information processing task faced by the central nervous system in estimating body spatial orientation and in controlling active body movement using an internal model referenced control strategy, a mathematical model for sensory conflict generation is developed. The model postulates a major dynamic functional role for sensory conflict signals in movement control, as well as in sensory-motor adaptation. It accounts for the role of active movement in creating motion sickness symptoms in some experimental circumstance, and in alleviating them in others. The relationship between motion sickness produced by sensory rearrangement and that resulting from external motion disturbances is explicitly defined. A nonlinear conflict averaging model is proposed which describes dynamic aspects of experimentally observed subjective discomfort sensation, and suggests resulting behaviours. The model admits several possibilities for adaptive mechanisms which do not involve internal model updating. Further systematic efforts to experimentally refine and validate the model are indicated.

76 FR 60962 - Noise Exposure Map Update for Buffalo Niagara International Airport, Buffalo, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... International Airport, under the provisions of 49 U.S.C. 47501 et seq. (Aviation Safety and Noise Abatement Act...''), effective September 20, 2011. Under 49 U.S.C. section 47503 of the Aviation Safety and Noise Abatement Act... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Noise Exposure Map Update for Buffalo...

Update on the genomics and basic biology of Brachypodium: International Brachypodium Initiative (IBI).

PubMed

Catalan, Pilar; Chalhoub, Boulos; Chochois, Vincent; Garvin, David F; Hasterok, Robert; Manzaneda, Antonio J; Mur, Luis A J; Pecchioni, Nicola; Rasmussen, Søren K; Vogel, John P; Voxeur, Aline

2014-07-01

The scientific presentations at the First International Brachypodium Conference (abstracts available at http://www.brachy2013.unimore.it) are evidence of the widespread adoption of Brachypodium distachyon as a model system. Furthermore, the wide range of topics presented (genome evolution, roots, abiotic and biotic stress, comparative genomics, natural diversity, and cell walls) demonstrates that the Brachypodium research community has achieved a critical mass of tools and has transitioned from resource development to addressing biological questions, particularly those unique to grasses. Copyright © 2014 Elsevier Ltd. All rights reserved.

Modeling and Analysis of Target Echo and Clutter in Range-Dependent Bistatic Environments: FY13 Annual Report for ONR

DTIC Science & Technology

2013-09-30

Intergovernmental Oceanographic Commission (IOC) (of UNESCO ) and the International Hydrographic Organization (IHO), British Oceanographic Data... LA , USA, 27 Nov – 1 Dec 2007. [PT09] John S. Perkins and Eric I. Thorsos. Update on the reverberation modeling workshops. J. Acoust. Soc. Am...Undersea Research Centre, La Spezia, Italy, 2008. Conference held at Villa Marigola, Lerici, Italy, 9–12 September 2008. [ZAS10] Mario Zampolli

A Unified Approach to Joint Regional/Teleseismic Calibration and Event Location with a 3D Earth Model

DTIC Science & Technology

2010-09-01

raytracing and travel-time calculation in 3D Earth models, such as the finite-difference eikonal method (e.g., Podvin and Lecomte, 1991), fast...by Reiter and Rodi (2009) in constructing JWM. Two teleseismic data sets were considered, both extracted from the EHB database (Engdahl et al...extracted from the updated EHB database distributed by the International Seismological Centre (http://www.isc.ac.uk/EHB/index.html). The new database

76 FR 5825 - U.S.-Korea Free Trade Agreement: Passenger Vehicle Sector Update

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-02

...: Passenger Vehicle Sector Update AGENCY: United States International Trade Commission. ACTION: Institution of...) instituted investigation No. 332-523, U.S.-Korea Free Trade Agreement: Passenger Vehicle Sector Update. DATES... concluded negotiations to modify the FTA, including certain provisions relating to the passenger vehicle...

Interagency Report on Orbital Debris, 1995

NASA Technical Reports Server (NTRS)

1995-01-01

This 1995 report updates the findings and recommendations of the 1989 report and reflects the authors' progress in understanding and managing the orbital debris environment. It provides an up-to-date portrait of their measurement, modeling, and mitigation efforts; and a set of recommendations outlining specific steps they should pursue, both domestically and internationally, to minimize the potential hazard posed by orbital debris.

Synthesizing information-update functions using off-line symbolic processing

NASA Technical Reports Server (NTRS)

Rosenschein, Stanley J.

1990-01-01

This paper explores the synthesis of programs that track dynamic conditions in their environment. An approach is proposed in which the designer specifies, in a declarative language, aspects of the environment in which the program will be embedded. This specification is then automatically compiled into a program that, when executed, updates internal data structures so as to maintain as an invariant a desired correspondence between internal data structures and states of the external environment. This approach retains much of the flexibility of declarative programming while guaranteeing a hard bound on the execution time of information-update functions.

Earth Observing System Covariance Realism Updates

NASA Technical Reports Server (NTRS)

Ojeda Romero, Juan A.; Miguel, Fred

2017-01-01

This presentation will be given at the International Earth Science Constellation Mission Operations Working Group meetings June 13-15, 2017 to discuss the Earth Observing System Covariance Realism updates.

Anticipation from sensation: using anticipating synchronization to stabilize a system with inherent sensory delay.

PubMed

Eberle, Henry; Nasuto, Slawomir J; Hayashi, Yoshikatsu

2018-03-01

We present a novel way of using a dynamical model for predictive tracking control that can adapt to a wide range of delays without parameter update. This is achieved by incorporating the paradigm of anticipating synchronization (AS), where a 'slave' system predicts a 'master' via delayed self-feedback. By treating the delayed output of the plant as one half of a 'sensory' AS coupling, the plant and an internal dynamical model can be synchronized such that the plant consistently leads the target's motion. We use two simulated robotic systems with differing arrangements of the plant and internal model ('parallel' and 'serial') to demonstrate that this form of control adapts to a wide range of delays without requiring the parameters of the controller to be changed.

Impact of aircraft emissions on air quality in the vicinity of airports. Volume II. An updated model assessment of aircraft generated air pollution at LAX, JFK, and ORD. Final report Jan 1978-Jul 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamartino, R.J.; Smith, D.G.; Bremer, S.A.

1980-07-01

This report documents the results of the Federal Aviation Administration (FAA)/Environmental Protection Agency (EPA) air quality study which has been conducted to assess the impact of aircraft emissions of carbon monoxide (CO), hydrocarbons (HC), and oxides of nitrogen (NOx) in the vicinity of airports. This assessment includes the results of recent modeling and monitoring efforts at Washington National (DCA), Los Angeles International (LAX), Dulles International (IAD), and Lakeland, Florida airports and an updated modeling of aircraft generated pollution at LAX, John F. Kennedy (JFK) and Chicago O'Hare (ORD) airports. The Airport Vicinity Air Pollution (AVAP) model which was designed formore » use at civil airports was used in this assessment. In addition the results of the application of the military version of the AVAP model the Air Quality Assessment Model (AQAM), are summarized. Both the results of the pollution monitoring analyses in Volume I and the modeling studies in Volume II suggest that: maximum hourly average CO concentrations from aircraft are unlikely to exceed 5 parts per million (ppm) in areas of public exposure and are thus small in comparison to the National Ambient Air Quality Standard of 35 ppm; maximum hourly HC concentrations from aircraft can exceed 0.25 ppm over an area several times the size of the airport; and annual average NO2 concentrations from aircraft are estimated to contribute only 10 to 20 percent of the NAAQS limit level.« less

Impact of state updating and multi-parametric ensemble for streamflow hindcasting in European river basins

NASA Astrophysics Data System (ADS)

Noh, S. J.; Rakovec, O.; Kumar, R.; Samaniego, L. E.

2015-12-01

Accurate and reliable streamflow prediction is essential to mitigate social and economic damage coming from water-related disasters such as flood and drought. Sequential data assimilation (DA) may facilitate improved streamflow prediction using real-time observations to correct internal model states. In conventional DA methods such as state updating, parametric uncertainty is often ignored mainly due to practical limitations of methodology to specify modeling uncertainty with limited ensemble members. However, if parametric uncertainty related with routing and runoff components is not incorporated properly, predictive uncertainty by model ensemble may be insufficient to capture dynamics of observations, which may deteriorate predictability. Recently, a multi-scale parameter regionalization (MPR) method was proposed to make hydrologic predictions at different scales using a same set of model parameters without losing much of the model performance. The MPR method incorporated within the mesoscale hydrologic model (mHM, http://www.ufz.de/mhm) could effectively represent and control uncertainty of high-dimensional parameters in a distributed model using global parameters. In this study, we evaluate impacts of streamflow data assimilation over European river basins. Especially, a multi-parametric ensemble approach is tested to consider the effects of parametric uncertainty in DA. Because augmentation of parameters is not required within an assimilation window, the approach could be more stable with limited ensemble members and have potential for operational uses. To consider the response times and non-Gaussian characteristics of internal hydrologic processes, lagged particle filtering is utilized. The presentation will be focused on gains and limitations of streamflow data assimilation and multi-parametric ensemble method over large-scale basins.

Advanced Test Reactor Core Modeling Update Project Annual Report for Fiscal Year 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

David W. Nigg; Devin A. Steuhm

2011-09-01

Legacy computational reactor physics software tools and protocols currently used for support of Advanced Test Reactor (ATR) core fuel management and safety assurance and, to some extent, experiment management are obsolete, inconsistent with the state of modern nuclear engineering practice, and are becoming increasingly difficult to properly verify and validate (V&V). Furthermore, the legacy staff knowledge required for application of these tools and protocols from the 1960s and 1970s is rapidly being lost due to staff turnover and retirements. In 2009 the Idaho National Laboratory (INL) initiated a focused effort to address this situation through the introduction of modern high-fidelitymore » computational software and protocols, with appropriate V&V, within the next 3-4 years via the ATR Core Modeling and Simulation and V&V Update (or 'Core Modeling Update') Project. This aggressive computational and experimental campaign will have a broad strategic impact on the operation of the ATR, both in terms of improved computational efficiency and accuracy for support of ongoing DOE programs as well as in terms of national and international recognition of the ATR National Scientific User Facility (NSUF). The ATR Core Modeling Update Project, targeted for full implementation in phase with the anticipated ATR Core Internals Changeout (CIC) in the 2014 time frame, began during the last quarter of Fiscal Year 2009, and has just completed its first full year. Key accomplishments so far have encompassed both computational as well as experimental work. A new suite of stochastic and deterministic transport theory based reactor physics codes and their supporting nuclear data libraries (SCALE, KENO-6, HELIOS, NEWT, and ATTILA) have been installed at the INL under various permanent sitewide license agreements and corresponding baseline models of the ATR and ATRC are now operational, demonstrating the basic feasibility of these code packages for their intended purpose. Furthermore, a capability for rigorous sensitivity analysis and uncertainty quantification based on the TSUNAMI system is being implemented and initial computational results have been obtained. This capability will have many applications in 2011 and beyond as a tool for understanding the margins of uncertainty in the new models as well as for validation experiment design and interpretation. Finally we note that although full implementation of the new computational models and protocols will extend over a period 3-4 years as noted above, interim applications in the much nearer term have already been demonstrated. In particular, these demonstrations included an analysis that was useful for understanding the cause of some issues in December 2009 that were triggered by a larger than acceptable discrepancy between the measured excess core reactivity and a calculated value that was based on the legacy computational methods. As the Modeling Update project proceeds we anticipate further such interim, informal, applications in parallel with formal qualification of the system under the applicable INL Quality Assurance procedures and standards.« less

Generalized role for the cerebellum in encoding internal models: evidence from semantic processing.

PubMed

Moberget, Torgeir; Gullesen, Eva Hilland; Andersson, Stein; Ivry, Richard B; Endestad, Tor

2014-02-19

The striking homogeneity of cerebellar microanatomy is strongly suggestive of a corresponding uniformity of function. Consequently, theoretical models of the cerebellum's role in motor control should offer important clues regarding cerebellar contributions to cognition. One such influential theory holds that the cerebellum encodes internal models, neural representations of the context-specific dynamic properties of an object, to facilitate predictive control when manipulating the object. The present study examined whether this theoretical construct can shed light on the contribution of the cerebellum to language processing. We reasoned that the cerebellum might perform a similar coordinative function when the context provided by the initial part of a sentence can be highly predictive of the end of the sentence. Using functional MRI in humans we tested two predictions derived from this hypothesis, building on previous neuroimaging studies of internal models in motor control. First, focal cerebellar activation-reflecting the operation of acquired internal models-should be enhanced when the linguistic context leads terminal words to be predictable. Second, more widespread activation should be observed when such predictions are violated, reflecting the processing of error signals that can be used to update internal models. Both predictions were confirmed, with predictability and prediction violations associated with increased blood oxygenation level-dependent signal in the posterior cerebellum (Crus I/II). Our results provide further evidence for cerebellar involvement in predictive language processing and suggest that the notion of cerebellar internal models may be extended to the language domain.

Accelerated Leach Testing of GLASS: ALTGLASS Version 3.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trivelpiece, Cory L.; Jantzen, Carol M.; Crawford, Charles L.

The Accelerated Leach Testing of GLASS (ALTGLASS) database is a collection of data from short- and long-term product consistency tests (PCT, ASTM C1285 A and B) on high level waste (HLW) as well as low activity waste (LAW) glasses. The database provides both U.S. and international researchers with an archive of experimental data for the purpose of studying, modeling, or validating existing models of nuclear waste glass corrosion. The ALTGLASS database is maintained and updated by researchers at the Savannah River National Laboratory (SRNL). This newest version, ALTGLASS Version 3.0, has been updated with an additional 503 rows of datamore » representing PCT results from corrosion experiments conducted in the United States by the Savannah River National Laboratory, Pacific Northwest National Laboratory, Argonne National Laboratory, and the Vitreous State Laboratory (SRNL, PNNL, ANL, VSL, respectively) as well as the National Nuclear Laboratory (NNL) in the United Kingdom.« less

Automating a human factors evaluation of graphical user interfaces for NASA applications: An update on CHIMES

NASA Technical Reports Server (NTRS)

Jiang, Jian-Ping; Murphy, Elizabeth D.; Bailin, Sidney C.; Truszkowski, Walter F.

1993-01-01

Capturing human factors knowledge about the design of graphical user interfaces (GUI's) and applying this knowledge on-line are the primary objectives of the Computer-Human Interaction Models (CHIMES) project. The current CHIMES prototype is designed to check a GUI's compliance with industry-standard guidelines, general human factors guidelines, and human factors recommendations on color usage. Following the evaluation, CHIMES presents human factors feedback and advice to the GUI designer. The paper describes the approach to modeling human factors guidelines, the system architecture, a new method developed to convert quantitative RGB primaries into qualitative color representations, and the potential for integrating CHIMES with user interface management systems (UIMS). Both the conceptual approach and its implementation are discussed. This paper updates the presentation on CHIMES at the first International Symposium on Ground Data Systems for Spacecraft Control.

Tribute to the contribution of Gerard Lallenment to structural dynamics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Los Alamos National Laboratory

The Society for Experimental Mechanics and the International Modal Analysis Conference recognize the remarkable contribution to experimental mechanics, mechanical engineering and structural dynamics of Professor Gerard Lallement, from the University of Franche-Comte, France. A special session is organized during the IMAC-XX to outline the many achievements of Gerard Lallement in the fields of modal analysis, structural system identification, the theory and practice of structural modification, component mode synthesis and finite element model updating. The purpose of this publication is not to provide an exhaustive account of Gerard Lallement's contribution to structural dynamics. Numerous references are provided that should help themore » interested reader learn more about the many aspects of his work. Instead, the significance of this work is illustrated by discussing the role of structural dynamics in industrial applications and its future challenges. The technical aspects of Gerard Lallement's work are illustrated with a discussion of structural modification, modeling error localization and model updating.« less

Benefits to the Simulation Training Community of a New ANSI Standard for the Exchange of Aero Simulation Models

NASA Technical Reports Server (NTRS)

Hildreth, Bruce L.; Jackson, E. Bruce

2009-01-01

The American Institute of Aeronautics Astronautics (AIAA) Modeling and Simulation Technical Committee is in final preparation of a new standard for the exchange of flight dynamics models. The standard will become an ANSI standard and is under consideration for submission to ISO for acceptance by the international community. The standard has some a spects that should provide benefits to the simulation training community. Use of the new standard by the training simulation community will reduce development, maintenance and technical refresh investment on each device. Furthermore, it will significantly lower the cost of performing model updates to improve fidelity or expand the envelope of the training device. Higher flight fidelity should result in better transfer of training, a direct benefit to the pilots under instruction. Costs of adopting the standard are minimal and should be paid back within the cost of the first use for that training device. The standard achie ves these advantages by making it easier to update the aerodynamic model. It provides a standard format for the model in a custom eXtensible Markup Language (XML) grammar, the Dynamic Aerospace Vehicle Exchange Markup Language (DAVE-ML). It employs an existing XML grammar, MathML, to describe the aerodynamic model in an input data file, eliminating the requirement for actual software compilation. The major components of the aero model become simply an input data file, and updates are simply new XML input files. It includes naming and axis system conventions to further simplify the exchange of information.

78 FR 73456 - List of Approved Spent Fuel Storage Casks: HI-STORM 100 Cask System; Amendment No. 9

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-06

...-2012-0052] RIN 3150-AJ12 List of Approved Spent Fuel Storage Casks: HI-STORM 100 Cask System; Amendment... International HI-STORM 100 Cask System listing within the ``List of Approved Spent Fuel Storage Casks'' to... requirements for the HI-STORM 100U part of the HI-STORM 100 Cask System and updates the thermal model and...

Trial-by-Trial Motor Cortical Correlates of a Rapidly Adapting Visuomotor Internal Model

PubMed Central

Ryu, Stephen I.

2017-01-01

Accurate motor control is mediated by internal models of how neural activity generates movement. We examined neural correlates of an adapting internal model of visuomotor gain in motor cortex while two macaques performed a reaching task in which the gain scaling between the hand and a presented cursor was varied. Previous studies of cortical changes during visuomotor adaptation focused on preparatory and perimovement epochs and analyzed trial-averaged neural data. Here, we recorded simultaneous neural population activity using multielectrode arrays and focused our analysis on neural differences in the period before the target appeared. We found that we could estimate the monkey's internal model of the gain using the neural population state during this pretarget epoch. This neural correlate depended on the gain experienced during recent trials and it predicted the speed of the subsequent reach. To explore the utility of this internal model estimate for brain–machine interfaces, we performed an offline analysis showing that it can be used to compensate for upcoming reach extent errors. Together, these results demonstrate that pretarget neural activity in motor cortex reflects the monkey's internal model of visuomotor gain on single trials and can potentially be used to improve neural prostheses. SIGNIFICANCE STATEMENT When generating movement commands, the brain is believed to use internal models of the relationship between neural activity and the body's movement. Visuomotor adaptation tasks have revealed neural correlates of these computations in multiple brain areas during movement preparation and execution. Here, we describe motor cortical changes in a visuomotor gain change task even before a specific movement is cued. We were able to estimate the gain internal model from these pretarget neural correlates and relate it to single-trial behavior. This is an important step toward understanding the sensorimotor system's algorithms for updating its internal models after specific movements and errors. Furthermore, the ability to estimate the internal model before movement could improve motor neural prostheses being developed for people with paralysis. PMID:28087767

Development of landsat-5 thematic mapper internal calibrator gain and offset table

USGS Publications Warehouse

Barsi, J.A.; Chander, G.; Micijevic, E.; Markham, B.L.; Haque, Md. O.

2008-01-01

The National Landsat Archive Production System (NLAPS) has been the primary processing system for Landsat data since U.S. Geological Survey (USGS) Earth Resources Observation and Science Center (EROS) started archiving Landsat data. NLAPS converts raw satellite data into radiometrically and geometrically calibrated products. NLAPS has historically used the Internal Calibrator (IC) to calibrate the reflective bands of the Landsat-5 Thematic Mapper (TM), even though the lamps in the IC were less stable than the TM detectors, as evidenced by vicarious calibration results. In 2003, a major effort was made to model the actual TM gain change and to update NLAPS to use this model rather than the unstable IC data for radiometric calibration. The model coefficients were revised in 2007 to reflect greater understanding of the changes in the TM responsivity. While the calibration updates are important to users with recently processed data, the processing system no longer calculates the original IC gain or offset. For specific applications, it is useful to have a record of the gain and offset actually applied to the older data. Thus, the NLAPS calibration database was used to generate estimated daily values for the radiometric gain and offset that might have been applied to TM data. This paper discusses the need for and generation of the NLAPSIC gain and offset tables. A companion paper covers the application of and errors associated with using these tables.

'DIRTMAP2': Dust and Palaeoclimate.

NASA Astrophysics Data System (ADS)

Maher, B.

2008-12-01

The influence of dust on climate, through changes in the radiative properties of the atmosphere and/or the CO2 content of the oceans and atmosphere (through iron fertilisation of high nutrient, low chlorophyll, HNLC, regions of the world's oceans), remains a poorly quantified and actively changing element of the Earth's climate system. Dust-cycle models presently employ a relatively simple representation of dust properties; these simplifications may severely limit the realism of simulations of the impact of changes in dust loading on either or both radiative forcing and biogeochemical cycling. Further, whilst state-of-the-art models achieve reasonable estimates of dust deposition in the far-field (i.e. at ocean locations), they under-estimate - by an order of magnitude - levels of dust deposition over the continents, unless glacigenic dust production is explicitly and spatially represented. The 'DIRTMAP2' working group aims to address these problems directly, through a series of explicitly interacting contributions from the international modelling and palaeo-data communities. A key aim of the project is to produce an updated version of the DIRTMAP database ('DIRTMAP2'), incorporating (a) records and age models newly available since ~ 2001, (b) longer records, and especially high-resolution records, that will target time windows also focused on by other international research programs (e.g. DO8/9, MIS5), (c) metadata to allow quality-control issues to be dealt with objectively, (d) information on mineralogy and isotopes relevant to provenancing, radiative forcing and iron bioavailability, and (e) enhanced characterisation of the aeolian component of existing records. This update will be coordinated with work (led by Karen Kohfeld) to expand the DIRTMAP database to incorporate information on marine productivity and improved sedimentation rate estimation techniques. It will also build upon a recently-developed dust model evaluation tool for current climate (e.g. Miller et al. 2006) to enable application of this and other evaluative models to palaeoclimate simulations. We invite colleagues to contribute to this update; the DIRTMAP2 database will shortly be accessible from the University of Lancaster website.

Update in the methodology of the chronic stress paradigm: internal control matters

PubMed Central

2011-01-01

To date, the reliability of induction of a depressive-like state using chronic stress models is confronted by many methodological limitations. We believe that the modifications to the stress paradigm in mice proposed herein allow some of these limitations to be overcome. Here, we discuss a variant of the standard stress paradigm, which results in anhedonia. This anhedonic state was defined by a decrease in sucrose preference that was not exhibited by all animals. As such, we propose the use of non-anhedonic, stressed mice as an internal control in experimental mouse models of depression. The application of an internal control for the effects of stress, along with optimized behavioural testing, can enable the analysis of biological correlates of stress-induced anhedonia versus the consequences of stress alone in a chronic-stress depression model. This is illustrated, for instance, by distinct physiological and molecular profiles in anhedonic and non-anhedonic groups subjected to stress. These results argue for the use of a subgroup of individuals who are negative for the induction of a depressive phenotype during experimental paradigms of depression as an internal control, for more refined modeling of this disorder in animals. PMID:21524310

Update in the methodology of the chronic stress paradigm: internal control matters.

PubMed

Strekalova, Tatyana; Couch, Yvonne; Kholod, Natalia; Boyks, Marco; Malin, Dmitry; Leprince, Pierre; Steinbusch, Harry Mw

2011-04-27

To date, the reliability of induction of a depressive-like state using chronic stress models is confronted by many methodological limitations. We believe that the modifications to the stress paradigm in mice proposed herein allow some of these limitations to be overcome. Here, we discuss a variant of the standard stress paradigm, which results in anhedonia. This anhedonic state was defined by a decrease in sucrose preference that was not exhibited by all animals. As such, we propose the use of non-anhedonic, stressed mice as an internal control in experimental mouse models of depression. The application of an internal control for the effects of stress, along with optimized behavioural testing, can enable the analysis of biological correlates of stress-induced anhedonia versus the consequences of stress alone in a chronic-stress depression model. This is illustrated, for instance, by distinct physiological and molecular profiles in anhedonic and non-anhedonic groups subjected to stress. These results argue for the use of a subgroup of individuals who are negative for the induction of a depressive phenotype during experimental paradigms of depression as an internal control, for more refined modeling of this disorder in animals.

76 FR 22618 - Product List Update

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-22

... Postage International Reply Coupon Service International Business Reply Mail Service Money Orders Post... International Reply Coupon Service International Business Reply Mail Service Money Orders Post Office Box... and CP2009-62) International Business Reply Service Competitive Contract 1 (MC2009-14 and CP2009-20...

Piloting a Structured Practice Audit to Assess ACGME Milestones in Written Handoff Communication in Internal Medicine.

PubMed

Martin, Shannon K; Farnan, Jeanne M; McConville, John F; Arora, Vineet M

2015-06-01

Written communication skills are integral to patient care handoffs. Residency programs require feasible assessment tools that provide timely formative and summative feedback, ideally linked to the Accreditation Council for Graduate Medical Education Milestones. We describe the use of 1 such tool-UPDATED-to assess written handoff communication skills in internal medicine interns. During 2012-2013, the authors piloted a structured practice audit at 1 academic institution to audit written sign-outs completed by 45 interns, using the UPDATED tool, which scores 7 aspects of sign-out communication linked to milestones. Intern sign-outs were audited by trained faculty members throughout the year. Results were incorporated into intern performance reviews and Clinical Competency Committees. A total of 136 sign-outs were audited (averaging 3.1 audits per intern). In the first trimester, 14 interns (31%) had satisfactory audit results. Five interns (11%) had critical deficiencies and received immediate feedback, and the remaining 26 (58%) were assigned future audits due to missing audits or unsatisfactory scores. In the second trimester, 21 interns (68%) had satisfactory results, 1 had critical deficiencies, and 9 (29%) required future audits. Nine of the 10 remaining interns in the final trimester had satisfactory audits. Faculty time was estimated at 10 to 15 minutes per sign-out audited. The UPDATED audit is a milestone-based tool that can be used to assess written sign-out communication skills in internal medicine residency programs. Future work is planned to adapt the tool for use by senior supervisory residents to appraise sign-outs in real time.

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update

PubMed Central

Duff, Anthony P.; Durand, Dominique; Gabel, Frank; Hendrickson, Wayne A.; Hura, Greg L.; Jacques, David A.; Kirby, Nigel M.; Kwan, Ann H.; Pérez, Javier; Pollack, Lois; Ryan, Timothy M.; Sali, Andrej; Schneidman-Duhovny, Dina; Vachette, Patrice; Westbrook, John

2017-01-01

In 2012, preliminary guidelines were published addressing sample quality, data acquisition and reduction, presentation of scattering data and validation, and modelling for biomolecular small-angle scattering (SAS) experiments. Bio­molecular SAS has since continued to grow and authors have increasingly adopted the preliminary guidelines. In parallel, integrative/hybrid determination of biomolecular structures is a rapidly growing field that is expanding the scope of structural biology. For SAS to contribute maximally to this field, it is essential to ensure open access to the information required for evaluation of the quality of SAS samples and data, as well as the validity of SAS-based structural models. To this end, the preliminary guidelines for data presentation in a publication are reviewed and updated, and the deposition of data and associated models in a public archive is recommended. These guidelines and recommendations have been prepared in consultation with the members of the International Union of Crystallography (IUCr) Small-Angle Scattering and Journals Commissions, the Worldwide Protein Data Bank (wwPDB) Small-Angle Scattering Validation Task Force and additional experts in the field. PMID:28876235

A neural network simulating human reach-grasp coordination by continuous updating of vector positioning commands.

PubMed

Ulloa, Antonio; Bullock, Daniel

2003-10-01

We developed a neural network model to simulate temporal coordination of human reaching and grasping under variable initial grip apertures and perturbations of object size and object location/orientation. The proposed model computes reach-grasp trajectories by continuously updating vector positioning commands. The model hypotheses are (1) hand/wrist transport, grip aperture, and hand orientation control modules are coupled by a gating signal that fosters synchronous completion of the three sub-goals. (2) Coupling from transport and orientation velocities to aperture control causes maximum grip apertures that scale with these velocities and exceed object size. (3) Part of the aperture trajectory is attributable to an aperture-reducing passive biomechanical effect that is stronger for larger apertures. (4) Discrepancies between internal representations of targets partially inhibit the gating signal, leading to movement time increases that compensate for perturbations. Simulations of the model replicate key features of human reach-grasp kinematics observed under three experimental protocols. Our results indicate that no precomputation of component movement times is necessary for online temporal coordination of the components of reaching and grasping.

Recent Updates of A Multi-Phase Transport (AMPT) Model

NASA Astrophysics Data System (ADS)

Lin, Zi-Wei

2008-10-01

We will present recent updates to the AMPT model, a Monte Carlo transport model for high energy heavy ion collisions, since its first public release in 2004 and the corresponding detailed descriptions in Phys. Rev. C 72, 064901 (2005). The updates often result from user requests. Some of these updates expand the physics processes or descriptions in the model, while some updates improve the usability of the model such as providing the initial parton distributions or help avoid crashes on some operating systems. We will also explain how the AMPT model is being maintained and updated.

Anticipation from sensation: using anticipating synchronization to stabilize a system with inherent sensory delay

PubMed Central

Nasuto, Slawomir J.; Hayashi, Yoshikatsu

2018-01-01

We present a novel way of using a dynamical model for predictive tracking control that can adapt to a wide range of delays without parameter update. This is achieved by incorporating the paradigm of anticipating synchronization (AS), where a ‘slave’ system predicts a ‘master’ via delayed self-feedback. By treating the delayed output of the plant as one half of a ‘sensory’ AS coupling, the plant and an internal dynamical model can be synchronized such that the plant consistently leads the target’s motion. We use two simulated robotic systems with differing arrangements of the plant and internal model (‘parallel’ and ‘serial’) to demonstrate that this form of control adapts to a wide range of delays without requiring the parameters of the controller to be changed. PMID:29657750

Improving Hall Thruster Plume Simulation through Refined Characterization of Near-field Plasma Properties

NASA Astrophysics Data System (ADS)

Huismann, Tyler D.

Due to the rapidly expanding role of electric propulsion (EP) devices, it is important to evaluate their integration with other spacecraft systems. Specifically, EP device plumes can play a major role in spacecraft integration, and as such, accurate characterization of plume structure bears on mission success. This dissertation addresses issues related to accurate prediction of plume structure in a particular type of EP device, a Hall thruster. This is done in two ways: first, by coupling current plume simulation models with current models that simulate a Hall thruster's internal plasma behavior; second, by improving plume simulation models and thereby increasing physical fidelity. These methods are assessed by comparing simulated results to experimental measurements. Assessment indicates the two methods improve plume modeling capabilities significantly: using far-field ion current density as a metric, these approaches used in conjunction improve agreement with measurements by a factor of 2.5, as compared to previous methods. Based on comparison to experimental measurements, recent computational work on discharge chamber modeling has been largely successful in predicting properties of internal thruster plasmas. This model can provide detailed information on plasma properties at a variety of locations. Frequently, experimental data is not available at many locations that are of interest regarding computational models. Excepting the presence of experimental data, there are limited alternatives for scientifically determining plasma properties that are necessary as inputs into plume simulations. Therefore, this dissertation focuses on coupling current models that simulate internal thruster plasma behavior with plume simulation models. Further, recent experimental work on atom-ion interactions has provided a better understanding of particle collisions within plasmas. This experimental work is used to update collision models in a current plume simulation code. Previous versions of the code assume an unknown dependence between particles' pre-collision velocities and post-collision scattering angles. This dissertation focuses on updating several of these types of collisions by assuming a curve fit based on the measurements of atom-ion interactions, such that previously unknown angular dependences are well-characterized.

Survey Geometry and the Internal Consistency of Recent Cosmic Shear Measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Troxel, M.A.; et al.

We explore the impact of an update to the typical approximation for the shape noise term in the analytic covariance matrix for cosmic shear experiments that assumes the absence of survey boundary and mask effects. We present an exact expression for the number of galaxy pairs in this term based on the the survey mask, which leads to more than a factor of three increase in the shape noise on the largest measured scales for the Kilo-Degree Survey (KIDS-450) real-space cosmic shear data. We compare the result of this analytic expression to several alternative methods for measuring the shape noise from the data and find excellent agreement. This update to the covariance resolves any internal model tension evidenced by the previously large cosmological best-fitmore » $$\\chi^2$$ for the KiDS-450 cosmic shear data. The best-fit $$\\chi^2$$ is reduced from 161 to 121 for 118 degrees of freedom. We also apply a correction to how the multiplicative shear calibration uncertainty is included in the covariance. This change, along with a previously known update to the reported effective angular values of the data vector, jointly shift the inferred amplitude of the correlation function to higher values. We find that this improves agreement of the KiDS-450 cosmic shear results with Dark Energy Survey Year 1 and Planck results.« less

Application of IRI-Plas in Ionospheric Tomography and HF Communication Studies with Assimilation of GPS-TEC

NASA Astrophysics Data System (ADS)

Arikan, Feza; Gulyaeva, Tamara; Sezen, Umut; Arikan, Orhan; Toker, Cenk; Hakan Tuna, MR.; Erdem, Esra

2016-07-01

International Reference Ionosphere is the most acknowledged climatic model of ionosphere that provides electron density profile and hourly, monthly median values of critical layer parameters of the ionosphere for a desired location, date and time between 60 to 2,000 km altitude. IRI is also accepted as the International Standard Ionosphere model. Recently, the IRI model is extended to the Global Positioning System (GPS) satellite orbital range of 20,000 km. The new version is called IRI-Plas and it can be obtained from http://ftp.izmiran.ru/pub/izmiran /SPIM/. A user-friendly online version is also provided at www.ionolab.org as a space weather service. Total Electron Content (TEC), which is defined as the line integral of electron density on a given ray path, is an observable parameter that can be estimated from earth based GPS receivers in a cost-effective manner as GPS-TEC. One of the most important advantages of IRI-Plas is the possible input of GPS-TEC to update the background deterministic ionospheric model to the current ionospheric state. This option is highly useful in regional and global tomography studies and HF link assessments. IONOLAB group currently implements IRI-Plas as a background model and updates the ionospheric state using GPS-TEC in IONOLAB-CIT and IONOLAB-RAY algorithms. The improved state of ionosphere allows the most reliable 4-D imaging of electron density profiles and HF and satellite communication link simulations.This study is supported by TUBITAK 115E915 and joint TUBITAK 114E092 and AS CR 14/001.

Medical Updates Number 5 to the International Space Station Probability Risk Assessment (PRA) Model Using the Integrated Medical Model

NASA Technical Reports Server (NTRS)

Butler, Doug; Bauman, David; Johnson-Throop, Kathy

2011-01-01

The Integrated Medical Model (IMM) Project has been developing a probabilistic risk assessment tool, the IMM, to help evaluate in-flight crew health needs and impacts to the mission due to medical events. This package is a follow-up to a data package provided in June 2009. The IMM currently represents 83 medical conditions and associated ISS resources required to mitigate medical events. IMM end state forecasts relevant to the ISS PRA model include evacuation (EVAC) and loss of crew life (LOCL). The current version of the IMM provides the basis for the operational version of IMM expected in the January 2011 timeframe. The objectives of this data package are: 1. To provide a preliminary understanding of medical risk data used to update the ISS PRA Model. The IMM has had limited validation and an initial characterization of maturity has been completed using NASA STD 7009 Standard for Models and Simulation. The IMM has been internally validated by IMM personnel but has not been validated by an independent body external to the IMM Project. 2. To support a continued dialogue between the ISS PRA and IMM teams. To ensure accurate data interpretation, and that IMM output format and content meets the needs of the ISS Risk Management Office and ISS PRA Model, periodic discussions are anticipated between the risk teams. 3. To help assess the differences between the current ISS PRA and IMM medical risk forecasts of EVAC and LOCL. Follow-on activities are anticipated based on the differences between the current ISS PRA medical risk data and the latest medical risk data produced by IMM.

Situation Model Updating in Young and Older Adults: Global versus Incremental Mechanisms

PubMed Central

Bailey, Heather R.; Zacks, Jeffrey M.

2015-01-01

Readers construct mental models of situations described by text. Activity in narrative text is dynamic, so readers must frequently update their situation models when dimensions of the situation change. Updating can be incremental, such that a change leads to updating just the dimension that changed, or global, such that the entire model is updated. Here, we asked whether older and young adults make differential use of incremental and global updating. Participants read narratives containing changes in characters and spatial location and responded to recognition probes throughout the texts. Responses were slower when probes followed a change, suggesting that situation models were updated at changes. When either dimension changed, responses to probes for both dimensions were slowed; this provides evidence for global updating. Moreover, older adults showed stronger evidence of global updating than did young adults. One possibility is that older adults perform more global updating to offset reduced ability to manipulate information in working memory. PMID:25938248

Impact of aircraft emissions on air quality in the vicinity of airports. Volume I. Recent airport measurement programs, data analyses, and sub-model development. Final report Jan78-Jul 80

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamartino, R.J.; Smith, D.G.; Bremer, S.A.

1980-07-01

This report documents the results of the Federal Aviation Administration (FAA)/Environmental Protection Agency (EPA) air quality study which has been conducted to assess the impact of aircraft emissions of carbon monoxide (CO), hydrocarbons (HC), and oxides of nitrogen (NOx) in the vicinity of airports. This assessment includes the results of recent modeling and monitoring efforts at Washington National (DCA), Los Angeles International (LAX), Dulles International (IAD), and Lakeland, Florida airports and an updated modeling of aircraft generated pollution at LAX, John F. Kennedy (JFK) and Chicago O'Hare (ORD) airports. The Airport Vicinity Air Pollution (AVAP) model which was designed formore » use at civil airports was used in this assessment. In addition the results of the application of the military version of the AVAP model the Air Quality Assessment Model (AQAM), are summarized.« less

75 FR 62501 - Senior Executive Service Performance Review Board: Update

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

... AGENCY FOR INTERNATIONAL DEVELOPMENT Senior Executive Service Performance Review Board: Update... Development, Office of Inspector General's Senior Executive Service Performance Review Board. DATES: September... reference-- USAID OIG Senior Executive Service (SES) Performance Review Board). SUPPLEMENTARY INFORMATION: 5...

Marshburn updates software on the WHC UPA in the Node 3

NASA Image and Video Library

2013-01-17

ISS034-E-031133 (17 Jan. 2013) --- NASA astronaut Tom Marshburn, Expedition 34 flight engineer, updates software on the Waste and Hygiene Compartment?s Urine Processor Assembly in the Tranquility node of the International Space Station.

Marshburn updates software on the WHC UPA in the Node 3

NASA Image and Video Library

2013-01-17

ISS034-E-031130 (17 Jan. 2013) --- NASA astronaut Tom Marshburn, Expedition 34 flight engineer, updates software on the Waste and Hygiene Compartment?s Urine Processor Assembly in the Tranquility node of the International Space Station.

Finite element modelling and updating of a lively footbridge: The complete process

NASA Astrophysics Data System (ADS)

Živanović, Stana; Pavic, Aleksandar; Reynolds, Paul

2007-03-01

The finite element (FE) model updating technology was originally developed in the aerospace and mechanical engineering disciplines to automatically update numerical models of structures to match their experimentally measured counterparts. The process of updating identifies the drawbacks in the FE modelling and the updated FE model could be used to produce more reliable results in further dynamic analysis. In the last decade, the updating technology has been introduced into civil structural engineering. It can serve as an advanced tool for getting reliable modal properties of large structures. The updating process has four key phases: initial FE modelling, modal testing, manual model tuning and automatic updating (conducted using specialist software). However, the published literature does not connect well these phases, although this is crucial when implementing the updating technology. This paper therefore aims to clarify the importance of this linking and to describe the complete model updating process as applicable in civil structural engineering. The complete process consisting the four phases is outlined and brief theory is presented as appropriate. Then, the procedure is implemented on a lively steel box girder footbridge. It was found that even a very detailed initial FE model underestimated the natural frequencies of all seven experimentally identified modes of vibration, with the maximum error being almost 30%. Manual FE model tuning by trial and error found that flexible supports in the longitudinal direction should be introduced at the girder ends to improve correlation between the measured and FE-calculated modes. This significantly reduced the maximum frequency error to only 4%. It was demonstrated that only then could the FE model be automatically updated in a meaningful way. The automatic updating was successfully conducted by updating 22 uncertain structural parameters. Finally, a physical interpretation of all parameter changes is discussed. This interpretation is often missing in the published literature. It was found that the composite slabs were less stiff than originally assumed and that the asphalt layer contributed considerably to the deck stiffness.

Network of European regions using space technologies an update on the NEREUS constitution

NASA Astrophysics Data System (ADS)

Morelli, Marianna; Campostrini, Pierpaolo

2010-01-01

The EU and ESA space research and development programmes give a consolidated model for international cooperation. They represent a good framework to develop and enhance different initiatives at global, regional and local level. The impact of space activities covers different areas of interest such as: the development of Earth observation applications for environment monitoring and risk prevention and management, the development of satellite communications and information systems, the exploitation of global satellite positioning and navigation systems, the knowledge of the Universe, the utilisation of ground segment engineering. These activities involve also the regional and local governments. This is particularly evident if we look at the competences of the European regional governments. Several European regions deal with a number of issues in areas linked to space activities. In line with these reflections a number of European regional governments supported by the Committee of the Regions launched the idea to create a Network of European Regions Using Space technologies—NEREUS. This Network is an International non-profit association (AISBL— Association International Sans But Lucratif) under Belgian law. The aim of this paper is to review the course of the initiative since its launch in April 2006, giving an update of the work done for its constitution.

Efficient Ensemble State-Parameters Estimation Techniques in Ocean Ecosystem Models: Application to the North Atlantic

NASA Astrophysics Data System (ADS)

El Gharamti, M.; Bethke, I.; Tjiputra, J.; Bertino, L.

2016-02-01

Given the recent strong international focus on developing new data assimilation systems for biological models, we present in this comparative study the application of newly developed state-parameters estimation tools to an ocean ecosystem model. It is quite known that the available physical models are still too simple compared to the complexity of the ocean biology. Furthermore, various biological parameters remain poorly unknown and hence wrong specifications of such parameters can lead to large model errors. Standard joint state-parameters augmentation technique using the ensemble Kalman filter (Stochastic EnKF) has been extensively tested in many geophysical applications. Some of these assimilation studies reported that jointly updating the state and the parameters might introduce significant inconsistency especially for strongly nonlinear models. This is usually the case for ecosystem models particularly during the period of the spring bloom. A better handling of the estimation problem is often carried out by separating the update of the state and the parameters using the so-called Dual EnKF. The dual filter is computationally more expensive than the Joint EnKF but is expected to perform more accurately. Using a similar separation strategy, we propose a new EnKF estimation algorithm in which we apply a one-step-ahead smoothing to the state. The new state-parameters estimation scheme is derived in a consistent Bayesian filtering framework and results in separate update steps for the state and the parameters. Unlike the classical filtering path, the new scheme starts with an update step and later a model propagation step is performed. We test the performance of the new smoothing-based schemes against the standard EnKF in a one-dimensional configuration of the Norwegian Earth System Model (NorESM) in the North Atlantic. We use nutrients profile (up to 2000 m deep) data and surface partial CO2 measurements from Mike weather station (66o N, 2o E) to estimate different biological parameters of phytoplanktons and zooplanktons. We analyze the performance of the filters in terms of complexity and accuracy of the state and parameters estimates.

78 FR 18321 - International Code Council: The Update Process for the International Codes and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

... for Residential Construction in High Wind Regions. ICC 700: National Green Building Standard The..., coordinated, and necessary to regulate the built environment. Federal agencies frequently use these codes and... International Codes and Standards consist of the following: ICC Codes International Building Code. International...

75 FR 19944 - International Code Council: The Update Process for the International Codes and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-16

... for Residential Construction in High Wind Areas. ICC 700: National Green Building Standard. The... Codes and Standards that are comprehensive, coordinated, and necessary to regulate the built environment... International Codes and Standards consist of the following: ICC Codes International Building Code. International...

First Update of the Criteria for Certification of Chest Pain Units in Germany: Facelift or New Model?

PubMed

Breuckmann, Frank; Rassaf, Tienush

2016-03-01

In an effort to provide a systematic and specific standard-of-care for patients with acute chest pain, the German Cardiac Society introduced criteria for certification of specialized chest pain units (CPUs) in 2008, which have been replaced by a recent update published in 2015. We reviewed the development of CPU establishment in Germany during the past 7 years and compared and commented the current update of the certification criteria. As of October 2015, 228 CPUs in Germany have been successfully certified by the German Cardiac Society; 300 CPUs are needed for full coverage closing gaps in rural regions. Current changes of the criteria mainly affect guideline-adherent adaptions of diagnostic work-ups, therapeutic strategies, risk stratification, in-hospital timing and education, and quality measures, whereas the overall structure remained unchanged. Benchmarking by participation within the German CPU registry is encouraged. Even though the history is short, the concept of certified CPUs in Germany is accepted and successful underlined by its recent implementation in national and international guidelines. First registry data demonstrated a high standard of quality-of-care. The current update provides rational adaptions to new guidelines and developments without raising the level for successful certifications. A periodic release of fast-track updates with shorter time frames and an increase of minimum requirements should be considered.

Numerical model updating technique for structures using firefly algorithm

NASA Astrophysics Data System (ADS)

Sai Kubair, K.; Mohan, S. C.

2018-03-01

Numerical model updating is a technique used for updating the existing experimental models for any structures related to civil, mechanical, automobiles, marine, aerospace engineering, etc. The basic concept behind this technique is updating the numerical models to closely match with experimental data obtained from real or prototype test structures. The present work involves the development of numerical model using MATLAB as a computational tool and with mathematical equations that define the experimental model. Firefly algorithm is used as an optimization tool in this study. In this updating process a response parameter of the structure has to be chosen, which helps to correlate the numerical model developed with the experimental results obtained. The variables for the updating can be either material or geometrical properties of the model or both. In this study, to verify the proposed technique, a cantilever beam is analyzed for its tip deflection and a space frame has been analyzed for its natural frequencies. Both the models are updated with their respective response values obtained from experimental results. The numerical results after updating show that there is a close relationship that can be brought between the experimental and the numerical models.

Between universalism and relativism: a conceptual exploration of problems in formulating and applying international biomedical ethical guidelines.

PubMed

Tangwa, G B

2004-02-01

In this paper, the author attempts to explore some of the problems connected with the formulation and application of international biomedical ethical guidelines, with particular reference to Africa. Recent attempts at revising and updating some international medical ethical guidelines have been bedevilled by intractable controversies and wrangling regarding both the content and formulation. From the vantage position of relative familiarity with both African and Western contexts, and the privilege of having been involved in the revision and updating of one of the international ethical guidelines, the author reflects broadly on these issues and attempts prescribing an approach from both the theoretical and practical angles liable to mitigate, if not completely eliminate, some of the problems and difficulties.

77 FR 15019 - Revision of Regulations Implementing the Convention on International Trade in Endangered Species...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-14

... Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES); Updates Following... Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) by incorporating...

Proposed Reference Spectral Irradiance Standards to Improve Photovoltaic Concentrating System Design and Performance Evaluation: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Myers, D. R.; Emery, K. E.; Gueymard, C.

2002-05-01

This conference paper describes the American Society for Testing and Materials (ASTM), the International Electrotechnical Commission (IEC), and the International Standards Organization (ISO) standard solar terrestrial spectra (ASTM G-159, IEC-904-3, ISO 9845-1) provide standard spectra for photovoltaic performance applications. Modern terrestrial spectral radiation models and knowledge of atmospheric physics are applied to develop suggested revisions to update the reference spectra. We use a moderately complex radiative transfer model (SMARTS2) to produce the revised spectra. SMARTS2 has been validated against the complex MODTRAN radiative transfer code and spectral measurements. The model is proposed as an adjunct standard to reproduce the referencemore » spectra. The proposed spectra represent typical clear sky spectral conditions associated with sites representing reasonable photovoltaic energy production and weathering and durability climates. The proposed spectra are under consideration by ASTM.« less

Development of a Geomagnetic Storm Correction to the International Reference Ionosphere E-Region Electron Densities Using TIMED/SABER Observations

NASA Technical Reports Server (NTRS)

Mertens, C. J.; Xu, X.; Fernandez, J. R.; Bilitza, D.; Russell, J. M., III; Mlynczak, M. G.

2009-01-01

Auroral infrared emission observed from the TIMED/SABER broadband 4.3 micron channel is used to develop an empirical geomagnetic storm correction to the International Reference Ionosphere (IRI) E-region electron densities. The observation-based proxy used to develop the storm model is SABER-derived NO+(v) 4.3 micron volume emission rates (VER). A correction factor is defined as the ratio of storm-time NO+(v) 4.3 micron VER to a quiet-time climatological averaged NO+(v) 4.3 micron VER, which is linearly fit to available geomagnetic activity indices. The initial version of the E-region storm model, called STORM-E, is most applicable within the auroral oval region. The STORM-E predictions of E-region electron densities are compared to incoherent scatter radar electron density measurements during the Halloween 2003 storm events. Future STORM-E updates will extend the model outside the auroral oval.

Modeling The Skeleton Weight of an Adult Caucasian Man.

PubMed

Avtandilashvili, Maia; Tolmachev, Sergei Y

2018-05-17

The reference value for the skeleton weight of an adult male (10.5 kg) recommended by the International Commission on Radiological Protection in Publication 70 is based on weights of dissected skeletons from 44 individuals, including two U.S. Transuranium and Uranium Registries whole-body donors. The International Commission on Radiological Protection analysis of anatomical data from 31 individuals with known values of body height demonstrated significant correlation between skeleton weight and body height. The corresponding regression equation, Wskel (kg) = -10.7 + 0.119 × H (cm), published in International Commission on Radiological Protection Publication 70 is typically used to estimate the skeleton weight from body height. Currently, the U.S. Transuranium and Uranium Registries holds data on individual bone weights from a total of 40 male whole-body donors, which has provided a unique opportunity to update the International Commission on Radiological Protection skeleton weight vs. body height equation. The original International Commission on Radiological Protection Publication 70 and the new U.S. Transuranium and Uranium Registries data were combined in a set of 69 data points representing a group of 33- to 95-y-old individuals with body heights and skeleton weights ranging from 155 to 188 cm and 6.5 to 13.4 kg, respectively. Data were fitted with a linear least-squares regression. A significant correlation between the two parameters was observed (r = 0.28), and an updated skeleton weight vs. body height equation was derived: Wskel (kg) = -6.5 + 0.093 × H (cm). In addition, a correlation of skeleton weight with multiple variables including body height, body weight, and age was evaluated using multiple regression analysis, and a corresponding fit equation was derived: Wskel (kg) = -0.25 + 0.046 × H (cm) + 0.036 × Wbody (kg) - 0.012 × A (y). These equations will be used to estimate skeleton weights and, ultimately, total skeletal actinide activities for biokinetic modeling of U.S. Transuranium and Uranium Registries partial-body donation cases.

International Federation of Head Neck Oncology Society 5(th) World Congress/American Head Neck Society 2014 update.

PubMed

Sharma, Shilpi; Chaukar, Devendra A

2014-07-01

Head neck cancer is an important health problem with high morbidity and mortality. Early detection and adequate treatment improve prognosis significantly. Thus creating awareness among clinicians is an important step toward control of head neck cancer and reducing its overall burden. We here provide an update on the International Federation of Head Neck Oncology Society/American Head Neck Society 2014 held between July 26, 2014 and July 30, 2014 in New York.

Updating and improving methodology for prioritizing highway project locations on the strategic intermodal system : [summary].

DOT National Transportation Integrated Search

2016-05-01

Florida International University researchers examined the existing performance measures and the project prioritization method in the CMP and updated them to better reflect the current conditions and strategic goals of FDOT. They also developed visual...

Using EEG and stimulus context to probe the modelling of auditory-visual speech.

PubMed

Paris, Tim; Kim, Jeesun; Davis, Chris

2016-02-01

We investigated whether internal models of the relationship between lip movements and corresponding speech sounds [Auditory-Visual (AV) speech] could be updated via experience. AV associations were indexed by early and late event related potentials (ERPs) and by oscillatory power and phase locking. Different AV experience was produced via a context manipulation. Participants were presented with valid (the conventional pairing) and invalid AV speech items in either a 'reliable' context (80% AVvalid items) or an 'unreliable' context (80% AVinvalid items). The results showed that for the reliable context, there was N1 facilitation for AV compared to auditory only speech. This N1 facilitation was not affected by AV validity. Later ERPs showed a difference in amplitude between valid and invalid AV speech and there was significant enhancement of power for valid versus invalid AV speech. These response patterns did not change over the context manipulation, suggesting that the internal models of AV speech were not updated by experience. The results also showed that the facilitation of N1 responses did not vary as a function of the salience of visual speech (as previously reported); in post-hoc analyses, it appeared instead that N1 facilitation varied according to the relative time of the acoustic onset, suggesting for AV events N1 may be more sensitive to the relationship of AV timing than form. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

Guideline on terminology and definitions of updating clinical guidelines: The Updating Glossary.

PubMed

Martínez García, Laura; Pardo-Hernández, Hector; Sanabria, Andrea Juliana; Alonso-Coello, Pablo; Penman, Katrina; McFarlane, Emma

2018-03-01

The Guidelines International Network (G-I-N) Updating Guidelines Working Group launched an initiative to develop a glossary (the Updating Glossary) with domains, terms, definitions, and synonyms related to updating of clinical guidelines (CGs). The steering committee developed an initial list of domains, terms, definitions, and synonyms through brainstorming and discussion. The panel members participated in three rounds of feedback to discuss, refine, and clarify the proposed terms, definitions, and synonyms. Finally, the panel members were surveyed to assess their level of agreement regarding the glossary. Eighteen terms were identified and defined: (1) continuous updating, (2) decision to update, (3) fixed updating, (4) full updating, (5) impact of the new evidence, (6) partial updating, (7) prioritization process, (8) reporting process, (9) signal for an update, (10) surveillance process, (11) time of validity, (12) timeframe, (13) tools and resources, (14) up to date, (15) update cycle, (16) update unit, (17) updated version, and (18) updating strategy. Consensus was reached for all terms, definitions, and synonyms (median agreement scores ≥ 6); except for one term. The G-I-N Updating Guidelines Working Group assembled the Updating Glossary to facilitate and improve the knowledge exchange among CGs developers, researchers, and users. Copyright © 2017 Elsevier Inc. All rights reserved.

Challenges in Managing Trustworthy Large-scale Digital Science

NASA Astrophysics Data System (ADS)

Evans, B. J. K.

2017-12-01

The increased use of large-scale international digital science has opened a number of challenges for managing, handling, using and preserving scientific information. The large volumes of information are driven by three main categories - model outputs including coupled models and ensembles, data products that have been processing to a level of usability, and increasingly heuristically driven data analysis. These data products are increasingly the ones that are usable by the broad communities, and far in excess of the raw instruments data outputs. The data, software and workflows are then shared and replicated to allow broad use at an international scale, which places further demands of infrastructure to support how the information is managed reliably across distributed resources. Users necessarily rely on these underlying "black boxes" so that they are productive to produce new scientific outcomes. The software for these systems depend on computational infrastructure, software interconnected systems, and information capture systems. This ranges from the fundamentals of the reliability of the compute hardware, system software stacks and libraries, and the model software. Due to these complexities and capacity of the infrastructure, there is an increased emphasis of transparency of the approach and robustness of the methods over the full reproducibility. Furthermore, with large volume data management, it is increasingly difficult to store the historical versions of all model and derived data. Instead, the emphasis is on the ability to access the updated products and the reliability by which both previous outcomes are still relevant and can be updated for the new information. We will discuss these challenges and some of the approaches underway that are being used to address these issues.

76 FR 50414 - International Mail Manual; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-15

... POSTAL SERVICE 39 CFR Part 20 International Mail Manual; Incorporation by Reference AGENCY: Postal... Standards of the United States Postal Service, International Mail Manual (IMM[supreg]) dated April 17, 2011.... SUPPLEMENTARY INFORMATION: The International Mail Manual was issued on April 17, 2011, and was updated with...

Updated Results for the Wake Vortex Inverse Model

NASA Technical Reports Server (NTRS)

Robins, Robert E.; Lai, David Y.; Delisi, Donald P.; Mellman, George R.

2008-01-01

NorthWest Research Associates (NWRA) has developed an Inverse Model for inverting aircraft wake vortex data. The objective of the inverse modeling is to obtain estimates of the vortex circulation decay and crosswind vertical profiles, using time history measurements of the lateral and vertical position of aircraft vortices. The Inverse Model performs iterative forward model runs using estimates of vortex parameters, vertical crosswind profiles, and vortex circulation as a function of wake age. Iterations are performed until a user-defined criterion is satisfied. Outputs from an Inverse Model run are the best estimates of the time history of the vortex circulation derived from the observed data, the vertical crosswind profile, and several vortex parameters. The forward model, named SHRAPA, used in this inverse modeling is a modified version of the Shear-APA model, and it is described in Section 2 of this document. Details of the Inverse Model are presented in Section 3. The Inverse Model was applied to lidar-observed vortex data at three airports: FAA acquired data from San Francisco International Airport (SFO) and Denver International Airport (DEN), and NASA acquired data from Memphis International Airport (MEM). The results are compared with observed data. This Inverse Model validation is documented in Section 4. A summary is given in Section 5. A user's guide for the inverse wake vortex model is presented in a separate NorthWest Research Associates technical report (Lai and Delisi, 2007a).

2017 American Heart Association Focused Update on Pediatric Basic Life Support and Cardiopulmonary Resuscitation Quality: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

PubMed

Atkins, Dianne L; de Caen, Allan R; Berger, Stuart; Samson, Ricardo A; Schexnayder, Stephen M; Joyner, Benny L; Bigham, Blair L; Niles, Dana E; Duff, Jonathan P; Hunt, Elizabeth A; Meaney, Peter A

2018-01-02

This focused update to the American Heart Association guidelines for cardiopulmonary resuscitation (CPR) and emergency cardiovascular care follows the Pediatric Task Force of the International Liaison Committee on Resuscitation evidence review. It aligns with the International Liaison Committee on Resuscitation's continuous evidence review process, and updates are published when the International Liaison Committee on Resuscitation completes a literature review based on new science. This update provides the evidence review and treatment recommendation for chest compression-only CPR versus CPR using chest compressions with rescue breaths for children <18 years of age. Four large database studies were available for review, including 2 published after the "2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care." Two demonstrated worse 30-day outcomes with chest compression-only CPR for children 1 through 18 years of age, whereas 2 studies documented no difference between chest compression-only CPR and CPR using chest compressions with rescue breaths. When the results were analyzed for infants <1 year of age, CPR using chest compressions with rescue breaths was better than no CPR but was no different from chest compression-only CPR in 1 study, whereas another study observed no differences among chest compression-only CPR, CPR using chest compressions with rescue breaths, and no CPR. CPR using chest compressions with rescue breaths should be provided for infants and children in cardiac arrest. If bystanders are unwilling or unable to deliver rescue breaths, we recommend that rescuers provide chest compressions for infants and children. © 2017 American Heart Association, Inc.

Timing Interactions in Social Simulations: The Voter Model

NASA Astrophysics Data System (ADS)

Fernández-Gracia, Juan; Eguíluz, Víctor M.; Miguel, Maxi San

The recent availability of huge high resolution datasets on human activities has revealed the heavy-tailed nature of the interevent time distributions. In social simulations of interacting agents the standard approach has been to use Poisson processes to update the state of the agents, which gives rise to very homogeneous activity patterns with a well defined characteristic interevent time. As a paradigmatic opinion model we investigate the voter model and review the standard update rules and propose two new update rules which are able to account for heterogeneous activity patterns. For the new update rules each node gets updated with a probability that depends on the time since the last event of the node, where an event can be an update attempt (exogenous update) or a change of state (endogenous update). We find that both update rules can give rise to power law interevent time distributions, although the endogenous one more robustly. Apart from that for the exogenous update rule and the standard update rules the voter model does not reach consensus in the infinite size limit, while for the endogenous update there exist a coarsening process that drives the system toward consensus configurations.

Trial-by-Trial Motor Cortical Correlates of a Rapidly Adapting Visuomotor Internal Model.

PubMed

Stavisky, Sergey D; Kao, Jonathan C; Ryu, Stephen I; Shenoy, Krishna V

2017-02-15

Accurate motor control is mediated by internal models of how neural activity generates movement. We examined neural correlates of an adapting internal model of visuomotor gain in motor cortex while two macaques performed a reaching task in which the gain scaling between the hand and a presented cursor was varied. Previous studies of cortical changes during visuomotor adaptation focused on preparatory and perimovement epochs and analyzed trial-averaged neural data. Here, we recorded simultaneous neural population activity using multielectrode arrays and focused our analysis on neural differences in the period before the target appeared. We found that we could estimate the monkey's internal model of the gain using the neural population state during this pretarget epoch. This neural correlate depended on the gain experienced during recent trials and it predicted the speed of the subsequent reach. To explore the utility of this internal model estimate for brain-machine interfaces, we performed an offline analysis showing that it can be used to compensate for upcoming reach extent errors. Together, these results demonstrate that pretarget neural activity in motor cortex reflects the monkey's internal model of visuomotor gain on single trials and can potentially be used to improve neural prostheses. SIGNIFICANCE STATEMENT When generating movement commands, the brain is believed to use internal models of the relationship between neural activity and the body's movement. Visuomotor adaptation tasks have revealed neural correlates of these computations in multiple brain areas during movement preparation and execution. Here, we describe motor cortical changes in a visuomotor gain change task even before a specific movement is cued. We were able to estimate the gain internal model from these pretarget neural correlates and relate it to single-trial behavior. This is an important step toward understanding the sensorimotor system's algorithms for updating its internal models after specific movements and errors. Furthermore, the ability to estimate the internal model before movement could improve motor neural prostheses being developed for people with paralysis. Copyright © 2017 the authors 0270-6474/17/371721-12$15.00/0.

Experimental Validation of Model Updating and Damage Detection via Eigenvalue Sensitivity Methods with Artificial Boundary Conditions

DTIC Science & Technology

2017-09-01

VALIDATION OF MODEL UPDATING AND DAMAGE DETECTION VIA EIGENVALUE SENSITIVITY METHODS WITH ARTIFICIAL BOUNDARY CONDITIONS by Matthew D. Bouwense...VALIDATION OF MODEL UPDATING AND DAMAGE DETECTION VIA EIGENVALUE SENSITIVITY METHODS WITH ARTIFICIAL BOUNDARY CONDITIONS 5. FUNDING NUMBERS 6. AUTHOR...unlimited. EXPERIMENTAL VALIDATION OF MODEL UPDATING AND DAMAGE DETECTION VIA EIGENVALUE SENSITIVITY METHODS WITH ARTIFICIAL BOUNDARY

ERM model analysis for adaptation to hydrological model errors

NASA Astrophysics Data System (ADS)

Baymani-Nezhad, M.; Han, D.

2018-05-01

Hydrological conditions are changed continuously and these phenomenons generate errors on flood forecasting models and will lead to get unrealistic results. Therefore, to overcome these difficulties, a concept called model updating is proposed in hydrological studies. Real-time model updating is one of the challenging processes in hydrological sciences and has not been entirely solved due to lack of knowledge about the future state of the catchment under study. Basically, in terms of flood forecasting process, errors propagated from the rainfall-runoff model are enumerated as the main source of uncertainty in the forecasting model. Hence, to dominate the exciting errors, several methods have been proposed by researchers to update the rainfall-runoff models such as parameter updating, model state updating, and correction on input data. The current study focuses on investigations about the ability of rainfall-runoff model parameters to cope with three types of existing errors, timing, shape and volume as the common errors in hydrological modelling. The new lumped model, the ERM model, has been selected for this study to evaluate its parameters for its use in model updating to cope with the stated errors. Investigation about ten events proves that the ERM model parameters can be updated to cope with the errors without the need to recalibrate the model.

77 FR 64724 - International Mail Manual; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... POSTAL SERVICE 39 CFR Part 20 International Mail Manual; Incorporation by Reference AGENCY: Postal... Standards of the United States Postal Service, International Mail Manual (IMM[supreg]) dated June 24, 2012... International Mail Manual was issued on June 24, 2012, and was updated with postal bulletin revisions through...

Ocean regional circulation model sensitizes to resolution of the lateral boundary conditions

NASA Astrophysics Data System (ADS)

Pham, Van Sy; Hwang, Jin Hwan

2017-04-01

Dynamical downscaling with nested regional oceanographic models is an effective approach for forecasting operationally coastal weather and projecting long term climate on the ocean. Nesting procedures deliver the unwanted in dynamic downscaling due to the differences of numerical grid sizes and updating steps. Therefore, such unavoidable errors restrict the application of the Ocean Regional Circulation Model (ORCMs) in both short-term forecasts and long-term projections. The current work identifies the effects of errors induced by computational limitations during nesting procedures on the downscaled results of the ORCMs. The errors are quantitatively evaluated for each error source and its characteristics by the Big-Brother Experiments (BBE). The BBE separates identified errors from each other and quantitatively assess the amount of uncertainties employing the same model to simulate for both nesting and nested model. Here, we focus on discussing errors resulting from two main matters associated with nesting procedures. They should be the spatial grids' differences and the temporal updating steps. After the diverse cases from separately running of the BBE, a Taylor diagram was adopted to analyze the results and suggest an optimization intern of grid size and updating period and domain sizes. Key words: lateral boundary condition, error, ocean regional circulation model, Big-Brother Experiment. Acknowledgement: This research was supported by grants from the Korean Ministry of Oceans and Fisheries entitled "Development of integrated estuarine management system" and a National Research Foundation of Korea (NRF) Grant (No. 2015R1A5A 7037372) funded by MSIP of Korea. The authors thank the Integrated Research Institute of Construction and Environmental Engineering of Seoul National University for administrative support.

Contextual cuing contributes to the independent modification of multiple internal models for vocal control

PubMed Central

Keough, Dwayne

2011-01-01

Research on the control of visually guided limb movements indicates that the brain learns and continuously updates an internal model that maps the relationship between motor commands and sensory feedback. A growing body of work suggests that an internal model that relates motor commands to sensory feedback also supports vocal control. There is evidence from arm-reaching studies that shows that when provided with a contextual cue, the motor system can acquire multiple internal models, which allows an animal to adapt to different perturbations in diverse contexts. In this study we show that trained singers can rapidly acquire multiple internal models regarding voice fundamental frequency (F0). These models accommodate different perturbations to ongoing auditory feedback. Participants heard three musical notes and reproduced each one in succession. The musical targets could serve as a contextual cue to indicate which direction (up or down) feedback would be altered on each trial; however, participants were not explicitly instructed to use this strategy. When participants were gradually exposed to altered feedback adaptation was observed immediately following vocal onset. Aftereffects were target specific and did not influence vocal productions on subsequent trials. When target notes were no longer a contextual cue, adaptation occurred during altered feedback trials and evidence for trial-by-trial adaptation was found. These findings indicate that the brain is exceptionally sensitive to the deviations between auditory feedback and the predicted consequence of a motor command during vocalization. Moreover, these results indicate that, with contextual cues, the vocal control system may maintain multiple internal models that are capable of independent modification during different tasks or environments. PMID:21346208

A review of statistical updating methods for clinical prediction models.

PubMed

Su, Ting-Li; Jaki, Thomas; Hickey, Graeme L; Buchan, Iain; Sperrin, Matthew

2018-01-01

A clinical prediction model is a tool for predicting healthcare outcomes, usually within a specific population and context. A common approach is to develop a new clinical prediction model for each population and context; however, this wastes potentially useful historical information. A better approach is to update or incorporate the existing clinical prediction models already developed for use in similar contexts or populations. In addition, clinical prediction models commonly become miscalibrated over time, and need replacing or updating. In this article, we review a range of approaches for re-using and updating clinical prediction models; these fall in into three main categories: simple coefficient updating, combining multiple previous clinical prediction models in a meta-model and dynamic updating of models. We evaluated the performance (discrimination and calibration) of the different strategies using data on mortality following cardiac surgery in the United Kingdom: We found that no single strategy performed sufficiently well to be used to the exclusion of the others. In conclusion, useful tools exist for updating existing clinical prediction models to a new population or context, and these should be implemented rather than developing a new clinical prediction model from scratch, using a breadth of complementary statistical methods.

Between universalism and relativism: a conceptual exploration of problems in formulating and applying international biomedical ethical guidelines

PubMed Central

Tangwa, G

2004-01-01

In this paper, the author attempts to explore some of the problems connected with the formulation and application of international biomedical ethical guidelines, with particular reference to Africa. Recent attempts at revising and updating some international medical ethical guidelines have been bedevilled by intractable controversies and wrangling regarding both the content and formulation. From the vantage position of relative familiarity with both African and Western contexts, and the privilege of having been involved in the revision and updating of one of the international ethical guidelines, the author reflects broadly on these issues and attempts prescribing an approach from both the theoretical and practical angles liable to mitigate, if not completely eliminate, some of the problems and difficulties. PMID:14872078

Recommendations on the diagnosis, treatment and monitoring of late-onset hypogonadism in men - a suggested update.

PubMed

Lunenfeld, Bruno; Mskhalaya, George; Kalinchenko, Svetlana; Tishova, Yulia

2013-12-01

Recommendations on the diagnosis, treatment and monitoring of late-onset hypogonadism (LOH) in men were first published by ISSAM in 2002 In 2005, and, in 2008, updated recommendations were published in the International Journal of Andrology, the Journal of Andrology, the Aging Male and European Urology. Towards discussions at the next ISSAM/ESSAM meeting in Moscow, 29 November 2013, we suggest the following update.

An Update to the NASA Reference Solar Sail Thrust Model

NASA Technical Reports Server (NTRS)

Heaton, Andrew F.; Artusio-Glimpse, Alexandra B.

2015-01-01

An optical model of solar sail material originally derived at JPL in 1978 has since served as the de facto standard for NASA and other solar sail researchers. The optical model includes terms for specular and diffuse reflection, thermal emission, and non-Lambertian diffuse reflection. The standard coefficients for these terms are based on tests of 2.5 micrometer Kapton sail material coated with 100 nm of aluminum on the front side and chromium on the back side. The original derivation of these coefficients was documented in an internal JPL technical memorandum that is no longer available. Additionally more recent optical testing has taken place and different materials have been used or are under consideration by various researchers for solar sails. Here, where possible, we re-derive the optical coefficients from the 1978 model and update them to accommodate newer test results and sail material. The source of the commonly used value for the front side non-Lambertian coefficient is not clear, so we investigate that coefficient in detail. Although this research is primarily designed to support the upcoming NASA NEA Scout and Lunar Flashlight solar sail missions, the results are also of interest to the wider solar sail community.

WHO expert committee on specifications for pharmaceutical preparations. Fortieth report.

PubMed

2006-01-01

This report presents the recommendations of an international group of experts convened by the World Health Organization to consider matters concerning the quality assurance of pharmaceuticals and specifications for drug substances and dosage forms. The report is complemented by a number of annexes. These include: a list of available International Chemical Reference Substances and International Infrared Spectra; supplementary guidelines on good manufacturing practices for heating, ventilation and air-conditioning systems for non-sterile pharmaceutical dosage forms; updated supplementary guidelines on good manufacturing practices for the manufacture of herbal medicines; supplementary guidelines on good manufacturing practices for validation; good distribution practices for pharmaceutical products; a model quality assurance system for procurement agencies (recommendations for quality assurance systems focusing on prequalification of products and manufacturers, purchasing, storage and distribution of pharmaceutical products); multisource (generic) pharmaceutical products: guidelines on registration requirements to establish interchangeability; a proposal to waive in vivo bioequivalence requirements for WHO Model List of Essential Medicines immediate-release, solid oral dosage forms; and additional guidance for organizations performing in vivo bioequivalence studies.

Soft sensor modelling by time difference, recursive partial least squares and adaptive model updating

NASA Astrophysics Data System (ADS)

Fu, Y.; Yang, W.; Xu, O.; Zhou, L.; Wang, J.

2017-04-01

To investigate time-variant and nonlinear characteristics in industrial processes, a soft sensor modelling method based on time difference, moving-window recursive partial least square (PLS) and adaptive model updating is proposed. In this method, time difference values of input and output variables are used as training samples to construct the model, which can reduce the effects of the nonlinear characteristic on modelling accuracy and retain the advantages of recursive PLS algorithm. To solve the high updating frequency of the model, a confidence value is introduced, which can be updated adaptively according to the results of the model performance assessment. Once the confidence value is updated, the model can be updated. The proposed method has been used to predict the 4-carboxy-benz-aldehyde (CBA) content in the purified terephthalic acid (PTA) oxidation reaction process. The results show that the proposed soft sensor modelling method can reduce computation effectively, improve prediction accuracy by making use of process information and reflect the process characteristics accurately.

Space-to-Ground: Quick Work: 10/13/2017

NASA Image and Video Library

2017-10-12

Astronauts continue maintenance outside the International Space Station...and artificial gravity on the station? Space to Ground is your weekly update on what's happening aboard the International Space Station.

Update rules and interevent time distributions: slow ordering versus no ordering in the voter model.

PubMed

Fernández-Gracia, J; Eguíluz, V M; San Miguel, M

2011-07-01

We introduce a general methodology of update rules accounting for arbitrary interevent time (IET) distributions in simulations of interacting agents. We consider in particular update rules that depend on the state of the agent, so that the update becomes part of the dynamical model. As an illustration we consider the voter model in fully connected, random, and scale-free networks with an activation probability inversely proportional to the time since the last action, where an action can be an update attempt (an exogenous update) or a change of state (an endogenous update). We find that in the thermodynamic limit, at variance with standard updates and the exogenous update, the system orders slowly for the endogenous update. The approach to the absorbing state is characterized by a power-law decay of the density of interfaces, observing that the mean time to reach the absorbing state might be not well defined. The IET distributions resulting from both update schemes show power-law tails.

Energy Savings Modeling and Inspection Guidelines for Commercial Building Federal Tax Deductions for Buildings in 2016 and Later

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deru, Michael; Field-Macumber, Kristin

This document provides guidance for modeling and inspecting energy-efficient property in commercial buildings for certification of the energy and power cost savings related to Section 179D of the Internal Revenue Code (IRC) enacted in Section 1331 of the 2005 Energy Policy Act (EPAct) of 2005, noted in Internal Revenue Service (IRS) Notices 2006-52 (IRS 2006), 2008-40 (IRS 2008) and 2012-26 (IRS 2012), and updated by the Protecting Americans from Tax Hikes (PATH) Act of 2015. Specifically, Section 179D provides federal tax deductions for energy-efficient property related to a commercial building's envelope; interior lighting; heating, ventilating, and air conditioning (HVAC); andmore » service hot water (SHW) systems. This document applies to buildings placed in service on or after January 1, 2016.« less

Soil erosion assessment - Mind the gap

NASA Astrophysics Data System (ADS)

Kim, Jongho; Ivanov, Valeriy Y.; Fatichi, Simone

2016-12-01

Accurate assessment of erosion rates remains an elusive problem because soil loss is strongly nonunique with respect to the main drivers. In addressing the mechanistic causes of erosion responses, we discriminate between macroscale effects of external factors - long studied and referred to as "geomorphic external variability", and microscale effects, introduced as "geomorphic internal variability." The latter source of erosion variations represents the knowledge gap, an overlooked but vital element of geomorphic response, significantly impacting the low predictability skill of deterministic models at field-catchment scales. This is corroborated with experiments using a comprehensive physical model that dynamically updates the soil mass and particle composition. As complete knowledge of microscale conditions for arbitrary location and time is infeasible, we propose that new predictive frameworks of soil erosion should embed stochastic components in deterministic assessments of external and internal types of geomorphic variability.

Updated Mortality Analysis of Radiation Workers at Rocketdyne (Atomics International), 1948-2008

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boice Jr JD, Colen SS, Mumma MT, Ellis ED, Eckerman DF, Leggett RW, Boecker BB, Brill B, Henderson BE

Updated analyses of mortality data are presented on 46,970 workers employed 1948-1999 at Rocketdyne (Atomics International). Overall, 5,801 workers were involved in radiation activities, including 2,232 who were monitored for intakes of radionuclides, and 41,169 workers were engaged in rocket testing or other non-radiation activities. The worker population is unique in that lifetime occupational doses from all places of employment were sought, updated and incorporated into the analyses. Further, radiation doses from intakes of 14 different radionuclides were calculated for 16 organs or tissues using biokinetic models of the International Commission on Radiation Protection (ICRP). Because only negligible exposures weremore » received by the 247 workers monitored for radiation activities after 1999, the mean dose from external radiation remained essentially the same at 13.5 mSv (maximum 1 Sv) as reported previously, as did the mean lung dose from external and internal radiation combined at 19.0 mSv (maximum 3.6 Sv). An additional 9 years of follow-up, from December 31,1999 through 2008, increased the person-years of observation for the radiation workers by 21.7% to 196,674 (mean 33.9 years) and the number of cancer deaths by 50% to 684. Analyses included external comparisons with the general population and the computation of standardized mortality ratios (SMRs) and internal comparisons using proportional hazards models and the computation of relative risks (RRs). A low SMR for all causes of death (SMR 0.82; 95% CI 0.78-0.85) continued to indicate that the Rocketdyne radiation workers were healthier than the general population and were less likely to die. The SMRs for all cancers taken together (SMR 0.88; 95% CI 0.81-0.95), lung cancer (SMR 0.87; 95% CI 0.76-1.00) and leukemia other than chronic lymphocytic leukemia (CLL) (SMR 1.04; 95% 0.67-1.53) were not significantly elevated. Cox regression analyses revealed no significant dose-response trends for any cancer. For all cancers excluding leukemia, the RR at 100 mSv was estimated as 0.98 (95% CI 0.82-1.17), and for all leukemia other than CLL it was 1.06 (95% CI 0.50-2.23). Uranium was the primary radionuclide contributing to internal exposures, but no significant increases in lung and kidney disease were seen. The extended follow-up reinforces the findings in the previous study in failing to observe a detectable increase in cancer deaths associated with radiation, but strong conclusions still cannot be drawn because of small numbers and relatively low career doses. Larger combined studies of early workers in the United States using similar methodologies are warranted to refine and clarify radiation risks after protracted exposures.« less

U.S. international travel and transportation trends : 2006 update

DOT National Transportation Integrated Search

2006-09-01

This report presents data on international travel to and from the United States. It combines data from a variety of sources (see box) to provide a more complete picture of U.S.-international travel than is available from individual sources. This repo...

COSPAR/PRBEM international working group activities report

NASA Astrophysics Data System (ADS)

Bourdarie, S.; Blake, B.; Cao, J. B.; Friedel, R.; Miyoshi, Y.; Panasyuk, M.; Underwood, C.

It is now clear to everybody that the current standard AE8 AP8 model for ionising particle specification in the radiation belts must be updated But such an objective is quite difficult to reach just as a reminder to develop AE8 AP8 model in the seventies was 10 persons full time for ten years It is clear that world-wide efforts must be combined because not any individual group has the human resource to perform these new models by themselves Under COSPAR umbrella an international group of expert well distributed around the world has been created to set up a common framework for everybody involved in this field Planned activities of the international group of experts are to - Define users needs - Provide guidelines for standard file format for ionising measurements - Set up guidelines to process in-situ data on a common basis - Decide in which form the new models will have to be - Centralise all progress done world-wide to advise the community - Try to organise world-wide activities as a project to ensure complementarities and more efficiencies between all efforts done Activities of this working group since its creation will be reported as well as future plans

Do we have an internal model of the outside world?

PubMed Central

Land, Michael F.

2014-01-01

Our phenomenal world remains stationary in spite of movements of the eyes, head and body. In addition, we can point or turn to objects in the surroundings whether or not they are in the field of view. In this review, I argue that these two features of experience and behaviour are related. The ability to interact with objects we cannot see implies an internal memory model of the surroundings, available to the motor system. And, because we maintain this ability when we move around, the model must be updated, so that the locations of object memories change continuously to provide accurate directional information. The model thus contains an internal representation of both the surroundings and the motions of the head and body: in other words, a stable representation of space. Recent functional MRI studies have provided strong evidence that this egocentric representation has a location in the precuneus, on the medial surface of the superior parietal cortex. This is a region previously identified with ‘self-centred mental imagery’, so it seems likely that the stable egocentric representation, required by the motor system, is also the source of our conscious percept of a stable world. PMID:24395972

Updated mortality analysis of radiation workers at Rocketdyne (Atomics International), 1948-2008

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boice, John; Cohen, Sarah; Mumma, Michael

Updated analyses of mortality data are presented on 5,801 radiation workers, including 2,232 monitored for radionuclide intakes, and 41,169 non-radiation workers employed 1948-1999 at Rocketdyne (Atomics International). The worker population is unique in that lifetime occupational doses from all places of employment were sought and incorporated into the analyses. Further, radiation doses from intakes of 14 different radionuclides were calculated for 16 organs or tissues using biokinetic models of the International Commission on Radiation Protection (ICRP). The mean dose from external radiation was 13.5 mSv (maximum 1 Sv), and the mean lung dose from external and internal radiation combined wasmore » 19.0 mSv (maximum 3.6 Sv). An additional nine years of follow-up, from December 31,1999 through 2008, increased the person-years of observation by 21.7% to 196,674 (mean 33.9 years) and the number of cancer deaths by 50% to 684. Analyses included comparisons with the general population and the computation of standardized mortality ratios (SMRs), and internal comparisons using proportional hazards models. All cancers taken together (SMR 0.88; 95% CI 0.81-0.95), lung cancer (SMR 0.87; 95% CI 0.76-1.00) and leukemia other than chronic lymphocytic leukemia (CLL) (SMR 1.04; 95% 0.67-1.53) were not significantly elevated. Cox regression analyses revealed no significant dose-response trends for any cancer. For all cancers excluding leukemia, the relative risk (RR) at 100 mSv was estimated as 0.98 (95% CI 0.82-1.17) and for all leukemia other than CLL it was 1.06 (95% CI 0.50-2.23). Uranium was the primary radionuclide contributing to internal exposures, but significant increases in lung and kidney disease were not seen. The extended follow-up re-enforces the findings in the previous study in failing to observe a detectable increase in cancer deaths associated with radiation, but strong conclusions still cannot be drawn because of small numbers and relatively low career doses. Larger combined studies of early workers in the United States following similar methodologies are warranted to refine and clarify radiation risks following protracted exposures.« less

Comparison of international guideline programs to evaluate and update the Dutch program for clinical guideline development in physical therapy

PubMed Central

Van der Wees, Philip J; Hendriks, Erik JM; Custers, Jan WH; Burgers, Jako S; Dekker, Joost; de Bie, Rob A

2007-01-01

Background Clinical guidelines are considered important instruments to improve quality in health care. Since 1998 the Royal Dutch Society for Physical Therapy (KNGF) produced evidence-based clinical guidelines, based on a standardized program. New developments in the field of guideline research raised the need to evaluate and update the KNGF guideline program. Purpose of this study is to compare different guideline development programs and review the KNGF guideline program for physical therapy in the Netherlands, in order to update the program. Method Six international guideline development programs were selected, and the 23 criteria of the AGREE Instrument were used to evaluate the guideline programs. Information about the programs was retrieved from published handbooks of the organizations. Also, the Dutch program for guideline development in physical therapy was evaluated using the AGREE criteria. Further comparison the six guideline programs was carried out using the following elements of the guideline development processes: Structure and organization; Preparation and initiation; Development; Validation; Dissemination and implementation; Evaluation and update. Results Compliance with the AGREE criteria of the guideline programs was high. Four programs addressed 22 AGREE criteria, and two programs addressed 20 AGREE criteria. The previous Dutch program for guideline development in physical therapy lacked in compliance with the AGREE criteria, meeting only 13 criteria. Further comparison showed that all guideline programs perform systematic literature searches to identify the available evidence. Recommendations are formulated and graded, based on evidence and other relevant factors. It is not clear how decisions in the development process are made. In particular, the process of translating evidence into practice recommendations can be improved. Conclusion As a result of international developments and consensus, the described processes for developing clinical practice guidelines have much in common. The AGREE criteria are common basis for the development of guidelines, although it is not clear how final decisions are made. Detailed comparison of the different guideline programs was used for updating the Dutch program. As a result the updated KNGF program complied with 22 AGREE criteria. International discussion is continuing and will be used for further improvement of the program. PMID:18036215

Comparison of international guideline programs to evaluate and update the Dutch program for clinical guideline development in physical therapy.

PubMed

Van der Wees, Philip J; Hendriks, Erik J M; Custers, Jan W H; Burgers, Jako S; Dekker, Joost; de Bie, Rob A

2007-11-23

Clinical guidelines are considered important instruments to improve quality in health care. Since 1998 the Royal Dutch Society for Physical Therapy (KNGF) produced evidence-based clinical guidelines, based on a standardized program. New developments in the field of guideline research raised the need to evaluate and update the KNGF guideline program. Purpose of this study is to compare different guideline development programs and review the KNGF guideline program for physical therapy in the Netherlands, in order to update the program. Six international guideline development programs were selected, and the 23 criteria of the AGREE Instrument were used to evaluate the guideline programs. Information about the programs was retrieved from published handbooks of the organizations. Also, the Dutch program for guideline development in physical therapy was evaluated using the AGREE criteria. Further comparison the six guideline programs was carried out using the following elements of the guideline development processes: Structure and organization; Preparation and initiation; Development; Validation; Dissemination and implementation; Evaluation and update. Compliance with the AGREE criteria of the guideline programs was high. Four programs addressed 22 AGREE criteria, and two programs addressed 20 AGREE criteria. The previous Dutch program for guideline development in physical therapy lacked in compliance with the AGREE criteria, meeting only 13 criteria. Further comparison showed that all guideline programs perform systematic literature searches to identify the available evidence. Recommendations are formulated and graded, based on evidence and other relevant factors. It is not clear how decisions in the development process are made. In particular, the process of translating evidence into practice recommendations can be improved. As a result of international developments and consensus, the described processes for developing clinical practice guidelines have much in common. The AGREE criteria are common basis for the development of guidelines, although it is not clear how final decisions are made. Detailed comparison of the different guideline programs was used for updating the Dutch program. As a result the updated KNGF program complied with 22 AGREE criteria. International discussion is continuing and will be used for further improvement of the program.

A Probabilistic Approach to Model Update

NASA Technical Reports Server (NTRS)

Horta, Lucas G.; Reaves, Mercedes C.; Voracek, David F.

2001-01-01

Finite element models are often developed for load validation, structural certification, response predictions, and to study alternate design concepts. In rare occasions, models developed with a nominal set of parameters agree with experimental data without the need to update parameter values. Today, model updating is generally heuristic and often performed by a skilled analyst with in-depth understanding of the model assumptions. Parameter uncertainties play a key role in understanding the model update problem and therefore probabilistic analysis tools, developed for reliability and risk analysis, may be used to incorporate uncertainty in the analysis. In this work, probability analysis (PA) tools are used to aid the parameter update task using experimental data and some basic knowledge of potential error sources. Discussed here is the first application of PA tools to update parameters of a finite element model for a composite wing structure. Static deflection data at six locations are used to update five parameters. It is shown that while prediction of individual response values may not be matched identically, the system response is significantly improved with moderate changes in parameter values.

Center Director's Update

NASA Image and Video Library

2016-03-01

In the Space Shuttle Atlantis exhibit facility at the Kennedy Space Center's Visitor Complex, guests get a close-up look at a plant growth experiment similar to one aboard the International Space Station. This followed a presentation by center director Bob Cabana who updated community leaders on current and future activities at the space center.

78 FR 68501 - International Standards on the Transport of Dangerous Goods

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-14

... include: Review of Working papers Working Group updates Regulatory Cooperation Council (RCC) Update... sessions, can be found on the United Nations Economic Commission for Europe (UNECE) Transport Division Web... its decisions on Working Papers. The Working Papers for the 26th session of the UNSCEGHS are located...

19 CFR 351.601 - Annual list and quarterly update of subsidies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 3 2011-04-01 2011-04-01 false Annual list and quarterly update of subsidies. 351.601 Section 351.601 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Subsidy Determinations Regarding Cheese Subject to an In-Quota Rate of...

19 CFR 351.601 - Annual list and quarterly update of subsidies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Annual list and quarterly update of subsidies. 351.601 Section 351.601 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE ANTIDUMPING AND COUNTERVAILING DUTIES Subsidy Determinations Regarding Cheese Subject to an In-Quota Rate of...

International Rett Syndrome Foundation

MedlinePlus

... of families and professionals. Sign up Join RettSyndrome.org Join our community to receive updates from the ... 2520 International: 1-513-874-3020 admin@rettsyndrome.org EIN 31-1682518 CFC 11046 Newsroom PSA Press ...

International ITS Program Assessment

DOT National Transportation Integrated Search

1995-08-01

THIS PAPER ATTEMPTS TO MAKE AN UPDATED COMPARISON OF WORLDWIDE ACTIVITIES IN INTELLIGENT TRANSPORTATION SYSTEMS (ITS) AND TO RECOMMEND A STRATEGY FOR CONTINUING INTERNATIONAL PROGRAM ASSESSMENT FOR DISCUSSION AT THE BENEFITS, EVALUATION AND COSTS (BE...

A technique for routinely updating the ITU-R database using radio occultation electron density profiles

NASA Astrophysics Data System (ADS)

Brunini, Claudio; Azpilicueta, Francisco; Nava, Bruno

2013-09-01

Well credited and widely used ionospheric models, such as the International Reference Ionosphere or NeQuick, describe the variation of the electron density with height by means of a piecewise profile tied to the F2-peak parameters: the electron density,, and the height, . Accurate values of these parameters are crucial for retrieving reliable electron density estimations from those models. When direct measurements of these parameters are not available, the models compute the parameters using the so-called ITU-R database, which was established in the early 1960s. This paper presents a technique aimed at routinely updating the ITU-R database using radio occultation electron density profiles derived from GPS measurements gathered from low Earth orbit satellites. Before being used, these radio occultation profiles are validated by fitting to them an electron density model. A re-weighted Least Squares algorithm is used for down-weighting unreliable measurements (occasionally, entire profiles) and to retrieve and values—together with their error estimates—from the profiles. These values are used to monthly update the database, which consists of two sets of ITU-R-like coefficients that could easily be implemented in the IRI or NeQuick models. The technique was tested with radio occultation electron density profiles that are delivered to the community by the COSMIC/FORMOSAT-3 mission team. Tests were performed for solstices and equinoxes seasons in high and low-solar activity conditions. The global mean error of the resulting maps—estimated by the Least Squares technique—is between and elec/m for the F2-peak electron density (which is equivalent to 7 % of the value of the estimated parameter) and from 2.0 to 5.6 km for the height (2 %).

Modeling stroke rehabilitation processes using the Unified Modeling Language (UML).

PubMed

Ferrante, Simona; Bonacina, Stefano; Pinciroli, Francesco

2013-10-01

In organising and providing rehabilitation procedures for stroke patients, the usual need for many refinements makes it inappropriate to attempt rigid standardisation, but greater detail is required concerning workflow. The aim of this study was to build a model of the post-stroke rehabilitation process. The model, implemented in the Unified Modeling Language, was grounded on international guidelines and refined following the clinical pathway adopted at local level by a specialized rehabilitation centre. The model describes the organisation of the rehabilitation delivery and it facilitates the monitoring of recovery during the process. Indeed, a system software was developed and tested to support clinicians in the digital administration of clinical scales. The model flexibility assures easy updating after process evolution. Copyright © 2013 Elsevier Ltd. All rights reserved.

Space to Ground: Launches and Landings: 06/08/2018

NASA Image and Video Library

2018-06-08

This week, one crew launched to the International Space Station, while another returned to Earth. NASA's Space to Ground is your weekly update on what's happening aboard the International Space Station.

Space-to-Ground: Genes in Space: 04/13/2018

NASA Image and Video Library

2018-04-12

Can the Polymerase Chain Reaction be used to study DNA alterations on the International Space Station? NASA's Space to Ground is your weekly update on what's happening aboard the International Space Station.

Arctic freshwater synthesis: Introduction

NASA Astrophysics Data System (ADS)

Prowse, T.; Bring, A.; Mârd, J.; Carmack, E.

2015-11-01

In response to a joint request from the World Climate Research Program's Climate and Cryosphere Project, the International Arctic Science Committee, and the Arctic Council's Arctic Monitoring and Assessment Program, an updated scientific assessment has been conducted of the Arctic Freshwater System (AFS), entitled the Arctic Freshwater Synthesis (AFSΣ). The major reason for joint request was an increasing concern that changes to the AFS have produced, and could produce even greater, changes to biogeophysical and socioeconomic systems of special importance to northern residents and also produce extra-Arctic climatic effects that will have global consequences. Hence, the key objective of the AFSΣ was to produce an updated, comprehensive, and integrated review of the structure and function of the entire AFS. The AFSΣ was organized around six key thematic areas: atmosphere, oceans, terrestrial hydrology, terrestrial ecology, resources and modeling, and the review of each coauthored by an international group of scientists and published as separate manuscripts in this special issue of Journal of Geophysical Research-Biogeosciences. This AFSΣ—Introduction reviews the motivations for, and foci of, previous studies of the AFS, discusses criteria used to define the domain of the AFS, and details key characteristics of the definition adopted for the AFSΣ.

Urinary incontinence in frail elderly persons: Report from the 5th International Consultation on Incontinence.

PubMed

Wagg, Adrian; Gibson, William; Ostaszkiewicz, Joan; Johnson, Theodore; Markland, Alayne; Palmer, Mary H; Kuchel, George; Szonyi, George; Kirschner-Hermanns, Ruth

2015-06-01

Evidence based guidelines for the management of frail older persons with urinary incontinence are rare. Those produced by the International Consultation on Incontinence represent an authoritative set of recommendations spanning all aspects of management. To update the recommendations of the 4th ICI. A series of systematic reviews and evidence updates were performed by members of the working group in order to update the 2009 recommendations. The resulting guidelines were presented at the 2012 meeting of the European Associatioon of Urology. Along with the revision of the treatment algorithm and accompanying text. There have been significant advances in several areas including pharmacological treatment of overactive bladder. The committee continue to notes the relative paucity of data concerning frail older persons and draw attention to knowledge gaps in this area. © 2014 Wiley Periodicals, Inc.

Dynamic model updating based on strain mode shape and natural frequency using hybrid pattern search technique

NASA Astrophysics Data System (ADS)

Guo, Ning; Yang, Zhichun; Wang, Le; Ouyang, Yan; Zhang, Xinping

2018-05-01

Aiming at providing a precise dynamic structural finite element (FE) model for dynamic strength evaluation in addition to dynamic analysis. A dynamic FE model updating method is presented to correct the uncertain parameters of the FE model of a structure using strain mode shapes and natural frequencies. The strain mode shape, which is sensitive to local changes in structure, is used instead of the displacement mode for enhancing model updating. The coordinate strain modal assurance criterion is developed to evaluate the correlation level at each coordinate over the experimental and the analytical strain mode shapes. Moreover, the natural frequencies which provide the global information of the structure are used to guarantee the accuracy of modal properties of the global model. Then, the weighted summation of the natural frequency residual and the coordinate strain modal assurance criterion residual is used as the objective function in the proposed dynamic FE model updating procedure. The hybrid genetic/pattern-search optimization algorithm is adopted to perform the dynamic FE model updating procedure. Numerical simulation and model updating experiment for a clamped-clamped beam are performed to validate the feasibility and effectiveness of the present method. The results show that the proposed method can be used to update the uncertain parameters with good robustness. And the updated dynamic FE model of the beam structure, which can correctly predict both the natural frequencies and the local dynamic strains, is reliable for the following dynamic analysis and dynamic strength evaluation.

Static and Dynamic Model Update of an Inflatable/Rigidizable Torus Structure

NASA Technical Reports Server (NTRS)

Horta, Lucas G.; Reaves, mercedes C.

2006-01-01

The present work addresses the development of an experimental and computational procedure for validating finite element models. A torus structure, part of an inflatable/rigidizable Hexapod, is used to demonstrate the approach. Because of fabrication, materials, and geometric uncertainties, a statistical approach combined with optimization is used to modify key model parameters. Static test results are used to update stiffness parameters and dynamic test results are used to update the mass distribution. Updated parameters are computed using gradient and non-gradient based optimization algorithms. Results show significant improvements in model predictions after parameters are updated. Lessons learned in the areas of test procedures, modeling approaches, and uncertainties quantification are presented.

77 FR 13198 - Product List Update

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-06

... Service International Business Reply Mail Service Money Orders Post Office Box Service Stamp Fulfillment... International Business Reply Mail Service Money Orders Post Office Box Service [Reserved for Product Description... Administrations 1 (MC2008-6 and CP2009-62) International Business Reply Service Competitive Contract 1 (MC2009-14...

Application of Artificial Boundary Conditions in Sensitivity-Based Updating of Finite Element Models

DTIC Science & Technology

2007-06-01

is known as the impedance matrix[ ]( )Z Ω . [ ] [ ] 1( ) ( )Z H −Ω = Ω (12) where [ ] 2( )Z K M j C ⎡ ⎤Ω = −Ω + Ω⎣ ⎦ (13) A. REDUCED ORDER...D.L. A correlation coefficient for modal vector analysis. Proceedings of 1st International Modal Analysis Conference, 1982, 110-116. Anton , H ... Rorres , C ., (2005). Elementary Linear Algebra. New York: John Wiley and Sons. Avitable, Peter (2001, January) Experimental Modal Analysis, A Simple

Human spaceflight and space adaptations: Computational simulation of gravitational unloading on the spine

NASA Astrophysics Data System (ADS)

Townsend, Molly T.; Sarigul-Klijn, Nesrin

2018-04-01

Living in reduced gravitational environments for a prolonged duration such, as a fly by mission to Mars or an extended stay at the international space station, affects the human body - in particular, the spine. As the spine adapts to spaceflight, morphological and physiological changes cause the mechanical integrity of the spinal column to be compromised, potentially endangering internal organs, nervous health, and human body mechanical function. Therefore, a high fidelity computational model and simulation of the whole human spine was created and validated for the purpose of investigating the mechanical integrity of the spine in crew members during exploratory space missions. A spaceflight exposed spine has been developed through the adaptation of a three-dimensional nonlinear finite element model with the updated Lagrangian formulation of a healthy ground-based human spine in vivo. Simulation of the porohyperelastic response of the intervertebral disc to mechanical unloading resulted in a model capable of accurately predicting spinal swelling/lengthening, spinal motion, and internal stress distribution. The curvature of this space adaptation exposed spine model was compared to a control terrestrial-based finite element model, indicating how the shape changed. Finally, the potential of injury sites to crew members are predicted for a typical 9 day mission.

ACVIM consensus update on Lyme borreliosis in dogs and cats

PubMed Central

Gerber, Bernhard; Goldstein, Richard E.; Labato, Mary Anna; Lappin, Michael R.; Moore, George E.

2018-01-01

An update of the 2006 American College of Veterinary Internal Medicine (ACVIM) Small Animal Consensus Statement on Lyme Disease in Dogs: Diagnosis, Treatment, and Prevention was presented at the 2016 ACVIM Forum in Denver, CO, followed by panel and audience discussion and a drafted consensus statement distributed online to diplomates for comment. The updated consensus statement is presented below. The consensus statement aims to provide guidance on the diagnosis, treatment, and prevention of Lyme borreliosis in dogs and cats. PMID:29566442

Modeling of Bulk Evaporation and Condensation

NASA Technical Reports Server (NTRS)

Anghaie, S.; Ding, Z.

1996-01-01

This report describes the modeling and mathematical formulation of the bulk evaporation and condensation involved in liquid-vapor phase change processes. An internal energy formulation, for these phase change processes that occur under the constraint of constant volume, was studied. Compared to the enthalpy formulation, the internal energy formulation has a more concise and compact form. The velocity and time scales of the interface movement were obtained through scaling analysis and verified by performing detailed numerical experiments. The convection effect induced by the density change was analyzed and found to be negligible compared to the conduction effect. Two iterative methods for updating the value of the vapor phase fraction, the energy based (E-based) and temperature based (T-based) methods, were investigated. Numerical experiments revealed that for the evaporation and condensation problems the E-based method is superior to the T-based method in terms of computational efficiency. The internal energy formulation and the E-based method were used to compute the bulk evaporation and condensation processes under different conditions. The evolution of the phase change processes was investigated. This work provided a basis for the modeling of thermal performance of multi-phase nuclear fuel elements under variable gravity conditions, in which the buoyancy convection due to gravity effects and internal heating are involved.

International Association for Promoting Geoethics (IAPG): an update on activities

NASA Astrophysics Data System (ADS)

Di Capua, Giuseppe; Bobrowsky, Peter; Kieffer, Susan; Peppoloni, Silvia; Tinti, Stefano

2016-04-01

The International Association for Promoting Geoethics (IAPG: http://www.geoethics.org) was founded on August 2012 to unite global geoscientists to raise the awareness of the scientific community regarding the importance of the ethical, social and cultural implications of geoscience research, education, and practice. IAPG is an international, multidisciplinary and scientific platform for discussion on ethical problems and dilemmas in Earth Sciences, promoting geoethical themes through scientific publications and conferences, strengthening the research base on geoethics, and focusing on case-studies as models for the development of effective and operative strategies. IAPG is legally recognized as a not-for-profit organization. It is a non-governmental, non-political, non-party institution, at all times free from racial, gender, religious or national prejudices. Its network continues to grow with more than 900 members in 103 countries, including 20 national sections. IAPG operates exclusively through donations and personal funds of its members. The results achieved since inception have been recognized by numerous international organizations. In particular, IAPG has obtained the status of affiliated organization by the International Union of Geological Sciences (IUGS), American Geosciences Institute (AGI), Geological Society of America (GSA), and the Geological Society of London (GSL). IAPG has enlarged its official relationships also through agreements on collaboration with other organizations, such as the American Geophysical Union (AGU), EuroGeoSurveys (EGS), European Federation of Geologists (EFG), Association of Environmental & Engineering Geologists (AEG), International Geoscience Education Organisation (IGEO), African Association of Women in Geosciences (AAWG), and others. IAPG considers publications as an indispensable activity to strengthen geoethics from a scientific point of view, so members are active in the publication of articles and editing of books on Geoethics with a peer-review process. Moreover, IAPG organizes sessions/symposia on geoethics in national and international congresses, thus encouraging a wide participation of the scientific community in the discussion on geoethical topics. This presentation provides an update on new results and numerous ongoing activities carried out by the IAPG with a brief look to future initiatives.

Sentry: An Automated Close Approach Monitoring System for Near-Earth Objects

NASA Astrophysics Data System (ADS)

Chamberlin, A. B.; Chesley, S. R.; Chodas, P. W.; Giorgini, J. D.; Keesey, M. S.; Wimberly, R. N.; Yeomans, D. K.

2001-11-01

In response to international concern about potential asteroid impacts on Earth, NASA's Near-Earth Object (NEO) Program Office has implemented a new system called ``Sentry'' to automatically update the orbits of all NEOs on a daily basis and compute Earth close approaches up to 100 years into the future. Results are published on our web site (http://neo.jpl.nasa.gov/) and updated orbits and ephemerides made available via the JPL Horizons ephemeris service (http://ssd.jpl.nasa.gov/horizons.html). Sentry collects new and revised astrometric observations from the Minor Planet Center (MPC) via their electronic circulars (MPECs) in near real time as well as radar and optical astrometry sent directly from observers. NEO discoveries and identifications are detected in MPECs and processed appropriately. In addition to these daily updates, Sentry synchronizes with each monthly batch of MPC astrometry and automatically updates all NEO observation files. Daily and monthly processing of NEO astrometry is managed using a queuing system which allows for manual intervention of selected NEOs without interfering with the automatic system. At the heart of Sentry is a fully automatic orbit determination program which handles outlier rejection and ensures convergence in the new solution. Updated orbital elements and their covariances are published via Horizons and our NEO web site, typically within 24 hours. A new version of Horizons, in development, will allow computation of ephemeris uncertainties using covariance data. The positions of NEOs with updated orbits are numerically integrated up to 100 years into the future and each close approach to any perturbing body in our dynamic model (all planets, Moon, Ceres, Pallas, Vesta) is recorded. Significant approaches are flagged for extended analysis including Monte Carlo studies. Results, such as minimum encounter distances and future Earth impact probabilities, are published on our NEO web site.

Central Heat Plant Modernization: FY98 Update and Recommendations.

DTIC Science & Technology

1999-12-01

Boiler and Pressure Vessel Code suggests an inspection frequency of 12 months for...28 April 1997). ASME International, Boiler and Pressure Vessel Code (ASME International, New York, NY, 1995). Bloomquist, R.G., J.D. Nimmons, and K...Services (HQDA, 28 April 1997). ASME International, Boiler and Pressure Vessel Code (ASME International, New York, NY, 1995). Bloomquist, R.G.,

Space-to-Ground: Some Serious Science: 02/08/2018

NASA Image and Video Library

2018-02-08

With a breather between spacewalks, it was time for some serious science on the International Space Station. NASA's Space to Ground is your weekly update on what's happening aboard the International Space Station.

Update on GPS Modernization Efforts

DTIC Science & Technology

2015-06-11

International Committee On Global Navigation Satellite Systems ( GNSS ) Department of Transportation • Federal Aviation Administration Satellite Block...90 for GNSS International Cooperation • 57 Authorized Allied Users - 25+ Years of Cooperation • GNSS - Europe - Galilee - China - COMPASS

DORIS Starec ground antenna characterization and impact on positioning

NASA Astrophysics Data System (ADS)

Tourain, C.; Moreaux, G.; Auriol, A.; Saunier, J.

2016-12-01

In a geodetic radio frequency observing system the phase center offsets and phase center variations of ground antennae are a fundamental component of mathematical models of the system observables. In this paper we describe work aimed at improving the DORIS Starec ground antenna phase center definition model. Seven antennas were analyzed in the Compact Antenna Test Range (CATR), a dedicated CNES facility. With respect to the manufacturer specified phase center offset, the measured antennae varied between -6 mm and +4 mm due to manufacturing variations. To solve this problem, discussions were held with the manufacturer, leading to an improvement of the manufacturing process. This work results in a reduction in the scatter to ±1 mm. The phase center position has been kept unchanged and associated phase law has been updated and provided to users of the International DORIS Service (IDS). This phase law is applicable to all Starec antennas (before and after manufacturing process consolidation) and is azimuth independent. An error budget taking into account these updated characteristics has been established for the antenna alone: ±2 mm on the horizontal plane and ±3 mm on the up component, maximum error values for antennas named type C (Saunier et al., 2016) produced with consolidated manufacturing process. Finally the impact of this updated characterization on positioning results has been analyzed and shows a scale offset only of the order of +12 mm for the Terrestrial Reference Frame.

A biokinetic model for systemic technetium in adult humans

DOE PAGES

Leggett, Richard Wayne; Giussani, Augusto

2015-04-10

The International Commission on Radiological Protection (ICRP) currently is updating its biokinetic and dosimetric models for internally deposited radionuclides. Technetium (Tc), the lightest element that exists only in radioactive form, has two important isotopes from the standpoint of potential risk to humans: the long-lived isotope 99Tm(T 1/2=2.1x10 5 y) is present in high concentration in nuclear waste, and the short-lived isotope 99mTc (T 1/2=6.02 h) is the most commonly used radionuclide in diagnostic nuclear medicine. This paper reviews data on the biological behavior of technetium and proposes a biokinetic model for systemic technetium in the adult human body formore » use in radiation protection. Compared with the ICRP s current occupational model for systemic technetium, the proposed model provides a more realistic description of the paths of movement of technetium in the body; provides greater consistency with experimental and medical data; and, for most radiosensitive organs, yields substantially different estimates of cumulative activity (total radioactive decays within the organ) following uptake of 99Tm or 99mTc to blood.« less

New Approaches in International Guidelines for Genetic Toxicology Assays: Latest Updates on OECD Guidelines

EPA Science Inventory

In March 2010, the 22nd meeting of the Working Group of National Coordinators of the OECD Test Guidelines Programme (WNT) approved a project for updating the Test Guidelines on genotoxicity, with Canada, the Netherlands, France and the USA identified as lead countries for this wo...

Taxonomy of the order Mononegavirales: update 2018.

PubMed

Amarasinghe, Gaya K; Aréchiga Ceballos, Nidia G; Banyard, Ashley C; Basler, Christopher F; Bavari, Sina; Bennett, Andrew J; Blasdell, Kim R; Briese, Thomas; Bukreyev, Alexander; Caì, Yíngyún; Calisher, Charles H; Campos Lawson, Cristine; Chandran, Kartik; Chapman, Colin A; Chiu, Charles Y; Choi, Kang-Seuk; Collins, Peter L; Dietzgen, Ralf G; Dolja, Valerian V; Dolnik, Olga; Domier, Leslie L; Dürrwald, Ralf; Dye, John M; Easton, Andrew J; Ebihara, Hideki; Echevarría, Juan E; Fooks, Anthony R; Formenty, Pierre B H; Fouchier, Ron A M; Freuling, Conrad M; Ghedin, Elodie; Goldberg, Tony L; Hewson, Roger; Horie, Masayuki; Hyndman, Timothy H; Jiāng, Dàohóng; Kityo, Robert; Kobinger, Gary P; Kondō, Hideki; Koonin, Eugene V; Krupovic, Mart; Kurath, Gael; Lamb, Robert A; Lee, Benhur; Leroy, Eric M; Maes, Piet; Maisner, Andrea; Marston, Denise A; Mor, Sunil Kumar; Müller, Thomas; Mühlberger, Elke; Ramírez, Víctor Manuel Neira; Netesov, Sergey V; Ng, Terry Fei Fan; Nowotny, Norbert; Palacios, Gustavo; Patterson, Jean L; Pawęska, Janusz T; Payne, Susan L; Prieto, Karla; Rima, Bertus K; Rota, Paul; Rubbenstroth, Dennis; Schwemmle, Martin; Siddell, Stuart; Smither, Sophie J; Song, Qisheng; Song, Timothy; Stenglein, Mark D; Stone, David M; Takada, Ayato; Tesh, Robert B; Thomazelli, Luciano Matsumiya; Tomonaga, Keizō; Tordo, Noël; Towner, Jonathan S; Vasilakis, Nikos; Vázquez-Morón, Sonia; Verdugo, Claudio; Volchkov, Viktor E; Wahl, Victoria; Walker, Peter J; Wang, David; Wang, Lin-Fa; Wellehan, James F X; Wiley, Michael R; Whitfield, Anna E; Wolf, Yuri I; Yè, Gōngyín; Zhāng, Yǒng-Zhèn; Kuhn, Jens H

2018-04-11

In 2018, the order Mononegavirales was expanded by inclusion of 1 new genus and 12 novel species. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV) and summarizes additional taxonomic proposals that may affect the order in the near future.

77 FR 21782 - International Conference on Harmonisation; Draft Guidance for Industry on E2C(R2) Periodic...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... electronic submission of individual case safety reports to regulatory authorities, automated data mining... Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (E2C guidance) and ``Addendum to E2C Clinical Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (addendum...

Off-Highway Gasoline Consuption Estimation Models Used in the Federal Highway Administration Attribution Process: 2008 Updates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hwang, Ho-Ling; Davis, Stacy Cagle

2009-12-01

This report is designed to document the analysis process and estimation models currently used by the Federal Highway Administration (FHWA) to estimate the off-highway gasoline consumption and public sector fuel consumption. An overview of the entire FHWA attribution process is provided along with specifics related to the latest update (2008) on the Off-Highway Gasoline Use Model and the Public Use of Gasoline Model. The Off-Highway Gasoline Use Model is made up of five individual modules, one for each of the off-highway categories: agricultural, industrial and commercial, construction, aviation, and marine. This 2008 update of the off-highway models was the secondmore » major update (the first model update was conducted during 2002-2003) after they were originally developed in mid-1990. The agricultural model methodology, specifically, underwent a significant revision because of changes in data availability since 2003. Some revision to the model was necessary due to removal of certain data elements used in the original estimation method. The revised agricultural model also made use of some newly available information, published by the data source agency in recent years. The other model methodologies were not drastically changed, though many data elements were updated to improve the accuracy of these models. Note that components in the Public Use of Gasoline Model were not updated in 2008. A major challenge in updating estimation methods applied by the public-use model is that they would have to rely on significant new data collection efforts. In addition, due to resource limitation, several components of the models (both off-highway and public-us models) that utilized regression modeling approaches were not recalibrated under the 2008 study. An investigation of the Environmental Protection Agency's NONROAD2005 model was also carried out under the 2008 model update. Results generated from the NONROAD2005 model were analyzed, examined, and compared, to the extent that is possible on the overall totals, to the current FHWA estimates. Because NONROAD2005 model was designed for emission estimation purposes (i.e., not for measuring fuel consumption), it covers different equipment populations from those the FHWA models were based on. Thus, a direct comparison generally was not possible in most sectors. As a result, NONROAD2005 data were not used in the 2008 update of the FHWA off-highway models. The quality of fuel use estimates directly affect the data quality in many tables published in the Highway Statistics. Although updates have been made to the Off-Highway Gasoline Use Model and the Public Use Gasoline Model, some challenges remain due to aging model equations and discontinuation of data sources.« less

Prediction-error variance in Bayesian model updating: a comparative study

NASA Astrophysics Data System (ADS)

Asadollahi, Parisa; Li, Jian; Huang, Yong

2017-04-01

In Bayesian model updating, the likelihood function is commonly formulated by stochastic embedding in which the maximum information entropy probability model of prediction error variances plays an important role and it is Gaussian distribution subject to the first two moments as constraints. The selection of prediction error variances can be formulated as a model class selection problem, which automatically involves a trade-off between the average data-fit of the model class and the information it extracts from the data. Therefore, it is critical for the robustness in the updating of the structural model especially in the presence of modeling errors. To date, three ways of considering prediction error variances have been seem in the literature: 1) setting constant values empirically, 2) estimating them based on the goodness-of-fit of the measured data, and 3) updating them as uncertain parameters by applying Bayes' Theorem at the model class level. In this paper, the effect of different strategies to deal with the prediction error variances on the model updating performance is investigated explicitly. A six-story shear building model with six uncertain stiffness parameters is employed as an illustrative example. Transitional Markov Chain Monte Carlo is used to draw samples of the posterior probability density function of the structure model parameters as well as the uncertain prediction variances. The different levels of modeling uncertainty and complexity are modeled through three FE models, including a true model, a model with more complexity, and a model with modeling error. Bayesian updating is performed for the three FE models considering the three aforementioned treatments of the prediction error variances. The effect of number of measurements on the model updating performance is also examined in the study. The results are compared based on model class assessment and indicate that updating the prediction error variances as uncertain parameters at the model class level produces more robust results especially when the number of measurement is small.

International Education: A Tertiary-Level Industry Update

ERIC Educational Resources Information Center

Naidoo, Vikash

2006-01-01

Recent developments in the international education industry are notable in three respects. First, international student mobility has more than doubled in the last two decades or so. Second, programme mobility encompassing distance education has also led to new forms of cross-border education. Third, institution mobility through such commercial…

Probabilistic Nowcasting of Low-Visibility Procedure States at Vienna International Airport During Cold Season

NASA Astrophysics Data System (ADS)

Kneringer, Philipp; Dietz, Sebastian J.; Mayr, Georg J.; Zeileis, Achim

2018-04-01

Airport operations are sensitive to visibility conditions. Low-visibility events may lead to capacity reduction, delays and economic losses. Different levels of low-visibility procedures (lvp) are enacted to ensure aviation safety. A nowcast of the probabilities for each of the lvp categories helps decision makers to optimally schedule their operations. An ordered logistic regression (OLR) model is used to forecast these probabilities directly. It is applied to cold season forecasts at Vienna International Airport for lead times of 30-min out to 2 h. Model inputs are standard meteorological measurements. The skill of the forecasts is accessed by the ranked probability score. OLR outperforms persistence, which is a strong contender at the shortest lead times. The ranked probability score of the OLR is even better than the one of nowcasts from human forecasters. The OLR-based nowcasting system is computationally fast and can be updated instantaneously when new data become available.

Neural correlates of sensory prediction errors in monkeys: evidence for internal models of voluntary self-motion in the cerebellum.

PubMed

Cullen, Kathleen E; Brooks, Jessica X

2015-02-01

During self-motion, the vestibular system makes essential contributions to postural stability and self-motion perception. To ensure accurate perception and motor control, it is critical to distinguish between vestibular sensory inputs that are the result of externally applied motion (exafference) and that are the result of our own actions (reafference). Indeed, although the vestibular sensors encode vestibular afference and reafference with equal fidelity, neurons at the first central stage of sensory processing selectively encode vestibular exafference. The mechanism underlying this reafferent suppression compares the brain's motor-based expectation of sensory feedback with the actual sensory consequences of voluntary self-motion, effectively computing the sensory prediction error (i.e., exafference). It is generally thought that sensory prediction errors are computed in the cerebellum, yet it has been challenging to explicitly demonstrate this. We have recently addressed this question and found that deep cerebellar nuclei neurons explicitly encode sensory prediction errors during self-motion. Importantly, in everyday life, sensory prediction errors occur in response to changes in the effector or world (muscle strength, load, etc.), as well as in response to externally applied sensory stimulation. Accordingly, we hypothesize that altering the relationship between motor commands and the actual movement parameters will result in the updating in the cerebellum-based computation of exafference. If our hypothesis is correct, under these conditions, neuronal responses should initially be increased--consistent with a sudden increase in the sensory prediction error. Then, over time, as the internal model is updated, response modulation should decrease in parallel with a reduction in sensory prediction error, until vestibular reafference is again suppressed. The finding that the internal model predicting the sensory consequences of motor commands adapts for new relationships would have important implications for understanding how responses to passive stimulation endure despite the cerebellum's ability to learn new relationships between motor commands and sensory feedback.

Assessing the performance of eight real-time updating models and procedures for the Brosna River

NASA Astrophysics Data System (ADS)

Goswami, M.; O'Connor, K. M.; Bhattarai, K. P.; Shamseldin, A. Y.

2005-10-01

The flow forecasting performance of eight updating models, incorporated in the Galway River Flow Modelling and Forecasting System (GFMFS), was assessed using daily data (rainfall, evaporation and discharge) of the Irish Brosna catchment (1207 km2), considering their one to six days lead-time discharge forecasts. The Perfect Forecast of Input over the Forecast Lead-time scenario was adopted, where required, in place of actual rainfall forecasts. The eight updating models were: (i) the standard linear Auto-Regressive (AR) model, applied to the forecast errors (residuals) of a simulation (non-updating) rainfall-runoff model; (ii) the Neural Network Updating (NNU) model, also using such residuals as input; (iii) the Linear Transfer Function (LTF) model, applied to the simulated and the recently observed discharges; (iv) the Non-linear Auto-Regressive eXogenous-Input Model (NARXM), also a neural network-type structure, but having wide options of using recently observed values of one or more of the three data series, together with non-updated simulated outflows, as inputs; (v) the Parametric Simple Linear Model (PSLM), of LTF-type, using recent rainfall and observed discharge data; (vi) the Parametric Linear perturbation Model (PLPM), also of LTF-type, using recent rainfall and observed discharge data, (vii) n-AR, an AR model applied to the observed discharge series only, as a naïve updating model; and (viii) n-NARXM, a naive form of the NARXM, using only the observed discharge data, excluding exogenous inputs. The five GFMFS simulation (non-updating) models used were the non-parametric and parametric forms of the Simple Linear Model and of the Linear Perturbation Model, the Linearly-Varying Gain Factor Model, the Artificial Neural Network Model, and the conceptual Soil Moisture Accounting and Routing (SMAR) model. As the SMAR model performance was found to be the best among these models, in terms of the Nash-Sutcliffe R2 value, both in calibration and in verification, the simulated outflows of this model only were selected for the subsequent exercise of producing updated discharge forecasts. All the eight forms of updating models for producing lead-time discharge forecasts were found to be capable of producing relatively good lead-1 (1-day ahead) forecasts, with R2 values almost 90% or above. However, for higher lead time forecasts, only three updating models, viz., NARXM, LTF, and NNU, were found to be suitable, with lead-6 values of R2 about 90% or higher. Graphical comparisons were made of the lead-time forecasts for the two largest floods, one in the calibration period and the other in the verification period.

Geomagnetic Jerks in the Swarm Era

NASA Astrophysics Data System (ADS)

Brown, William; Beggan, Ciaran; Macmillan, Susan

2016-08-01

The timely provision of geomagnetic observations as part of the European Space Agency (ESA) Swarm mission means up-to-date analysis and modelling of the Earth's magnetic field can be conducted rapidly in a manner not possible before. Observations from each of the three Swarm constellation satellites are available within 4 days and a database of close-to-definitive ground observatory measurements is updated every 3 months. This makes it possible to study very recent variations of the core magnetic field. Here we investigate rapid, unpredictable internal field variations known as geomagnetic jerks. Given that jerks represent (currently) unpredictable changes in the core field and have been identified to have happened in 2014 since Swarm was launched, we ask what impact this might have on the future accuracy of the International Geomagnetic Reference Field (IGRF). We assess the performance of each of the IGRF-12 secular variation model candidates in light of recent jerks, given that four of the nine candidates are novel physics-based predictive models.

Computational simulation of the creep-rupture process in filamentary composite materials

NASA Technical Reports Server (NTRS)

Slattery, Kerry T.; Hackett, Robert M.

1991-01-01

A computational simulation of the internal damage accumulation which causes the creep-rupture phenomenon in filamentary composite materials is developed. The creep-rupture process involves complex interactions between several damage mechanisms. A statistically-based computational simulation using a time-differencing approach is employed to model these progressive interactions. The finite element method is used to calculate the internal stresses. The fibers are modeled as a series of bar elements which are connected transversely by matrix elements. Flaws are distributed randomly throughout the elements in the model. Load is applied, and the properties of the individual elements are updated at the end of each time step as a function of the stress history. The simulation is continued until failure occurs. Several cases, with different initial flaw dispersions, are run to establish a statistical distribution of the time-to-failure. The calculations are performed on a supercomputer. The simulation results compare favorably with the results of creep-rupture experiments conducted at the Lawrence Livermore National Laboratory.

Measuring and Benchmarking Technical Efficiency of Public Hospitals in Tianjin, China

PubMed Central

Li, Hao; Dong, Siping

2015-01-01

China has long been stuck in applying traditional data envelopment analysis (DEA) models to measure technical efficiency of public hospitals without bias correction of efficiency scores. In this article, we have introduced the Bootstrap-DEA approach from the international literature to analyze the technical efficiency of public hospitals in Tianjin (China) and tried to improve the application of this method for benchmarking and inter-organizational learning. It is found that the bias corrected efficiency scores of Bootstrap-DEA differ significantly from those of the traditional Banker, Charnes, and Cooper (BCC) model, which means that Chinese researchers need to update their DEA models for more scientific calculation of hospital efficiency scores. Our research has helped shorten the gap between China and the international world in relative efficiency measurement and improvement of hospitals. It is suggested that Bootstrap-DEA be widely applied into afterward research to measure relative efficiency and productivity of Chinese hospitals so as to better serve for efficiency improvement and related decision making. PMID:26396090

An Online Risk Monitor System (ORMS) to Increase Safety and Security Levels in Industry

NASA Astrophysics Data System (ADS)

Zubair, M.; Rahman, Khalil Ur; Hassan, Mehmood Ul

2013-12-01

The main idea of this research is to develop an Online Risk Monitor System (ORMS) based on Living Probabilistic Safety Assessment (LPSA). The article highlights the essential features and functions of ORMS. The basic models and modules such as, Reliability Data Update Model (RDUM), running time update, redundant system unavailability update, Engineered Safety Features (ESF) unavailability update and general system update have been described in this study. ORMS not only provides quantitative analysis but also highlights qualitative aspects of risk measures. ORMS is capable of automatically updating the online risk models and reliability parameters of equipment. ORMS can support in the decision making process of operators and managers in Nuclear Power Plants.

Planned updates and refinements to the central valley hydrologic model, with an emphasis on improving the simulation of land subsidence in the San Joaquin Valley

USGS Publications Warehouse

Faunt, C.C.; Hanson, R.T.; Martin, P.; Schmid, W.

2011-01-01

California's Central Valley has been one of the most productive agricultural regions in the world for more than 50 years. To better understand the groundwater availability in the valley, the U.S. Geological Survey (USGS) developed the Central Valley hydrologic model (CVHM). Because of recent water-level declines and renewed subsidence, the CVHM is being updated to better simulate the geohydrologic system. The CVHM updates and refinements can be grouped into two general categories: (1) model code changes and (2) data updates. The CVHM updates and refinements will require that the model be recalibrated. The updated CVHM will provide a detailed transient analysis of changes in groundwater availability and flow paths in relation to climatic variability, urbanization, stream flow, and changes in irrigated agricultural practices and crops. The updated CVHM is particularly focused on more accurately simulating the locations and magnitudes of land subsidence. The intent of the updated CVHM is to help scientists better understand the availability and sustainability of water resources and the interaction of groundwater levels with land subsidence. ?? 2011 ASCE.

Planned updates and refinements to the Central Valley hydrologic model with an emphasis on improving the simulation of land subsidence in the San Joaquin Valley

USGS Publications Warehouse

Faunt, Claudia C.; Hanson, Randall T.; Martin, Peter; Schmid, Wolfgang

2011-01-01

California's Central Valley has been one of the most productive agricultural regions in the world for more than 50 years. To better understand the groundwater availability in the valley, the U.S. Geological Survey (USGS) developed the Central Valley hydrologic model (CVHM). Because of recent water-level declines and renewed subsidence, the CVHM is being updated to better simulate the geohydrologic system. The CVHM updates and refinements can be grouped into two general categories: (1) model code changes and (2) data updates. The CVHM updates and refinements will require that the model be recalibrated. The updated CVHM will provide a detailed transient analysis of changes in groundwater availability and flow paths in relation to climatic variability, urbanization, stream flow, and changes in irrigated agricultural practices and crops. The updated CVHM is particularly focused on more accurately simulating the locations and magnitudes of land subsidence. The intent of the updated CVHM is to help scientists better understand the availability and sustainability of water resources and the interaction of groundwater levels with land subsidence.

Hazardous properties and toxicological update of mercury: From fish food to human health safety perspective.

PubMed

Okpala, Charles Odilichukwu R; Sardo, Giacomo; Vitale, Sergio; Bono, Gioacchino; Arukwe, Augustine

2017-04-10

The mercury (Hg) poisoning of Minamata Bay of Japan widely activated a global attention to Hg toxicity and its potential consequences to the aquatic ecosystem and human health. This has resulted to an increased need for a dynamic assembly, contextualization, and quantification of both the current state-of-the-art and approaches for understanding the cause-and-effect relationships of Hg exposure. Thus, the objective of this present review is to provide both hazardous toxic properties and toxicological update of Hg, focusing on how it ultimately affects the aquatic biota to potentially produce human health effects. Primarily, we discussed processes that relate to Hg exposure, including immunological aspects and risk assessment, vulnerability, toxicokinetics, and toxicodynamics, using edible fish, swordfish (Xiphias gladius), as a model. In addition, we summarized available information about Hg concentration limits set by different governmental agencies, as recognized by national and international standardization authorities.

Obtaining manufactured geometries of deep-drawn components through a model updating procedure using geometric shape parameters

NASA Astrophysics Data System (ADS)

Balla, Vamsi Krishna; Coox, Laurens; Deckers, Elke; Plyumers, Bert; Desmet, Wim; Marudachalam, Kannan

2018-01-01

The vibration response of a component or system can be predicted using the finite element method after ensuring numerical models represent realistic behaviour of the actual system under study. One of the methods to build high-fidelity finite element models is through a model updating procedure. In this work, a novel model updating method of deep-drawn components is demonstrated. Since the component is manufactured with a high draw ratio, significant deviations in both profile and thickness distributions occurred in the manufacturing process. A conventional model updating, involving Young's modulus, density and damping ratios, does not lead to a satisfactory match between simulated and experimental results. Hence a new model updating process is proposed, where geometry shape variables are incorporated, by carrying out morphing of the finite element model. This morphing process imitates the changes that occurred during the deep drawing process. An optimization procedure that uses the Global Response Surface Method (GRSM) algorithm to maximize diagonal terms of the Modal Assurance Criterion (MAC) matrix is presented. This optimization results in a more accurate finite element model. The advantage of the proposed methodology is that the CAD surface of the updated finite element model can be readily obtained after optimization. This CAD model can be used for carrying out analysis, as it represents the manufactured part more accurately. Hence, simulations performed using this updated model with an accurate geometry, will therefore yield more reliable results.

Review of the International Society for Heart and Lung Transplantation Practice guidelines for management of heart failure in children.

PubMed

Colan, Steven D

2015-08-01

In 2004, practice guidelines for the management of heart failure in children by Rosenthal and colleagues were published in conjunction with the International Society for Heart and Lung Transplantation. These guidelines have not been updated or reviewed since that time. In general, there has been considerable controversy as to the utility and purpose of clinical practice guidelines, but there is general recognition that the relentless progress of medicine leads to the progressive irrelevance of clinical practice guidelines that do not undergo periodic review and updating. Paediatrics and paediatric cardiology, in particular, have had comparatively minimal participation in the clinical practice guidelines realm. As a result, most clinical practice guidelines either specifically exclude paediatrics from consideration, as has been the case for the guidelines related to cardiac failure in adults, or else involve clinical practice guidelines committees that include one or two paediatric cardiologists and produce guidelines that cannot reasonably be considered a consensus paediatric opinion. These circumstances raise a legitimate question as to whether the International Society for Heart and Lung Transplantation paediatric heart failure guidelines should be re-reviewed. The time, effort, and expense involved in producing clinical practice guidelines should be considered before recommending an update to the International Society for Heart and Lung Transplantation Paediatric Heart Failure guidelines. There are specific areas of rapid change in the evaluation and management of heart failure in children that are undoubtedly worthy of updating. These domains include areas such as use of serum and imaging biomarkers, wearable and implantable monitoring devices, and acute heart failure management and mechanical circulatory support. At the time the International Society for Heart and Lung Transplantation guidelines were published, echocardiographic tissue Doppler, 3 dimensional imaging, and strain and strain rate were either novel or non-existent and have now moved into the main stream. Cardiac magnetic resonance imaging (MRI) had very limited availability, and since that time imaging and assessment of myocardial iron content, delayed gadolinium enhancement, and extracellular volume have moved into the mainstream. The only devices discussed in the International Society for Heart and Lung Transplantation guidelines were extracorporeal membrane oxygenators, pacemakers, and defibrillators. Since that time, ventricular assist devices have become mainstream. Despite the relative lack of randomised controlled trials in paediatric heart failure, advances continue to occur. These advances warrant implementation of an update and review process, something that is best done under the auspices of the national and international cardiology societies. A joint activity that includes the International Society for Heart and Lung Transplantation, American College of Cardiology/American Heart Association, the Association for European Paediatric and Congenital Cardiology (AEPC), European Society of Cardiology, Canadian Cardiovascular Society, and others will have more credibility than independent efforts by any of these organisations.

Updated Histologic Classification of Adenomas and Carcinomas in the Colon of Carcinogen-treated Sprague-Dawley Rats.

PubMed

Rubio, Carlos A

2017-12-01

Recent studies have disclosed novel histological phenotypes of colon tumours in carcinogen-treated rats. The aim of this study was to update the current histological classification of colonic neoplasias in Sprague-Dawley (SD) rats. Archival sections from 398 SD rats having 408 neoplasias in previous experiments were re-evaluated. Of the 408 colonic neoplasias, 11% (44/408) were adenomas without invasive growth and 89% (364/408) invasive carcinomas. Out of the 44 adenomas, 82% were conventional (tubular or villous), 14% traditional serrated (TSA; with unlocked serrations or with closed microtubules) and 5% gut-associated lymphoid tissue (GALT)-associated adenomas. Out of 364 carcinomas, 57% were conventional carcinomas, 26% GALT carcinomas, 8% undifferentiated, 6% signet-ring cell carcinomas, and 4% traditional serrated carcinomas (TSC). Thus, conventional adenomas, conventional carcinomas and GALT-associated carcinomas predominated (p<0.05). The updated classification of colonic tumours in SD rats includes conventional adenomas, TSA, GALT-associated adenomas, conventional carcinomas, TSC, GALT-associated carcinomas, signet-ring cell carcinomas and undifferentiated carcinomas. Several of the histological phenotypes reported here are not included in any of the current classifications of colonic tumours in rodents. This updated classification fulfils the requirements for an animal model of human disease, inasmuch as similar histological phenotypes of colon neoplasias have been documented in humans. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops

PubMed Central

Phan, Andy; Mailey, Katherine; Saeki, Jessica; Gu, Xiaobo

2017-01-01

Accurate thermodynamic parameters improve RNA structure predictions and thus accelerate understanding of RNA function and the identification of RNA drug binding sites. Many viral RNA structures, such as internal ribosome entry sites, have internal loops and bulges that are potential drug target sites. Current models used to predict internal loops are biased toward small, symmetric purine loops, and thus poorly predict asymmetric, pyrimidine-rich loops with >6 nucleotides (nt) that occur frequently in viral RNA. This article presents new thermodynamic data for 40 pyrimidine loops, many of which can form UU or protonated CC base pairs. Uracil and protonated cytosine base pairs stabilize asymmetric internal loops. Accurate prediction rules are presented that account for all thermodynamic measurements of RNA asymmetric internal loops. New loop initiation terms for loops with >6 nt are presented that do not follow previous assumptions that increasing asymmetry destabilizes loops. Since the last 2004 update, 126 new loops with asymmetry or sizes greater than 2 × 2 have been measured. These new measurements significantly deepen and diversify the thermodynamic database for RNA. These results will help better predict internal loops that are larger, pyrimidine-rich, and occur within viral structures such as internal ribosome entry sites. PMID:28213527

Webmail: an Automated Web Publishing System

NASA Astrophysics Data System (ADS)

Bell, David

A system for publishing frequently updated information to the World Wide Web will be described. Many documents now hosted by the NOAO Web server require timely posting and frequent updates, but need only minor changes in markup or are in a standard format requiring only conversion to HTML. These include information from outside the organization, such as electronic bulletins, and a number of internal reports, both human and machine generated. Webmail uses procmail and Perl scripts to process incoming email messages in a variety of ways. This processing may include wrapping or conversion to HTML, posting to the Web or internal newsgroups, updating search indices or links on related pages, and sending email notification of the new pages to interested parties. The Webmail system has been in use at NOAO since early 1997 and has steadily grown to include fourteen recipes that together handle about fifty messages per week.

Quality Analysis on 3d Buidling Models Reconstructed from Uav Imagery

NASA Astrophysics Data System (ADS)

Jarzabek-Rychard, M.; Karpina, M.

2016-06-01

Recent developments in UAV technology and structure from motion techniques have effected that UAVs are becoming standard platforms for 3D data collection. Because of their flexibility and ability to reach inaccessible urban parts, drones appear as optimal solution for urban applications. Building reconstruction from the data collected with UAV has the important potential to reduce labour cost for fast update of already reconstructed 3D cities. However, especially for updating of existing scenes derived from different sensors (e.g. airborne laser scanning), a proper quality assessment is necessary. The objective of this paper is thus to evaluate the potential of UAV imagery as an information source for automatic 3D building modeling at LOD2. The investigation process is conducted threefold: (1) comparing generated SfM point cloud to ALS data; (2) computing internal consistency measures of the reconstruction process; (3) analysing the deviation of Check Points identified on building roofs and measured with a tacheometer. In order to gain deep insight in the modeling performance, various quality indicators are computed and analysed. The assessment performed according to the ground truth shows that the building models acquired with UAV-photogrammetry have the accuracy of less than 18 cm for the plannimetric position and about 15 cm for the height component.

Estimation of beam material random field properties via sensitivity-based model updating using experimental frequency response functions

NASA Astrophysics Data System (ADS)

Machado, M. R.; Adhikari, S.; Dos Santos, J. M. C.; Arruda, J. R. F.

2018-03-01

Structural parameter estimation is affected not only by measurement noise but also by unknown uncertainties which are present in the system. Deterministic structural model updating methods minimise the difference between experimentally measured data and computational prediction. Sensitivity-based methods are very efficient in solving structural model updating problems. Material and geometrical parameters of the structure such as Poisson's ratio, Young's modulus, mass density, modal damping, etc. are usually considered deterministic and homogeneous. In this paper, the distributed and non-homogeneous characteristics of these parameters are considered in the model updating. The parameters are taken as spatially correlated random fields and are expanded in a spectral Karhunen-Loève (KL) decomposition. Using the KL expansion, the spectral dynamic stiffness matrix of the beam is expanded as a series in terms of discretized parameters, which can be estimated using sensitivity-based model updating techniques. Numerical and experimental tests involving a beam with distributed bending rigidity and mass density are used to verify the proposed method. This extension of standard model updating procedures can enhance the dynamic description of structural dynamic models.

Summary of Expansions, Updates, and Results in GREET 2017 Suite of Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Michael; Elgowainy, Amgad; Han, Jeongwoo

This report provides a technical summary of the expansions and updates to the 2017 release of Argonne National Laboratory’s Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET®) model, including references and links to key technical documents related to these expansions and updates. The GREET 2017 release includes an updated version of the GREET1 (the fuel-cycle GREET model) and GREET2 (the vehicle-cycle GREET model), both in the Microsoft Excel platform and in the GREET.net modeling platform. Figure 1 shows the structure of the GREET Excel modeling platform. The .net platform integrates all GREET modules together seamlessly.

Updates to the Demographic and Spatial Allocation Models to ...

EPA Pesticide Factsheets

EPA's announced the availability of the final report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Version 2). This update furthered land change modeling by providing nationwide housing development scenarios up to 2100. This newest version includes updated population and land use data sets and addresses limitations identified in ICLUS v1 in both the migration and spatial allocation models. The companion user guide (Final Report) describes the development of ICLUS v2 and the updates that were made to the original data sets and the demographic and spatial allocation models. The GIS tool enables users to run SERGoM with the population projections developed for the ICLUS project and allows users to modify the spatial allocation housing density across the landscape.

Model Update of a Micro Air Vehicle (MAV) Flexible Wing Frame with Uncertainty Quantification

NASA Technical Reports Server (NTRS)

Reaves, Mercedes C.; Horta, Lucas G.; Waszak, Martin R.; Morgan, Benjamin G.

2004-01-01

This paper describes a procedure to update parameters in the finite element model of a Micro Air Vehicle (MAV) to improve displacement predictions under aerodynamics loads. Because of fabrication, materials, and geometric uncertainties, a statistical approach combined with Multidisciplinary Design Optimization (MDO) is used to modify key model parameters. Static test data collected using photogrammetry are used to correlate with model predictions. Results show significant improvements in model predictions after parameters are updated; however, computed probabilities values indicate low confidence in updated values and/or model structure errors. Lessons learned in the areas of wing design, test procedures, modeling approaches with geometric nonlinearities, and uncertainties quantification are all documented.

To Your Health: NLM update transcript - Improving the international response to infectious illness

MedlinePlus

... international responses to the bird flu, Ebola, and Zika viruses are a byproduct of how public health ... in 2009, Ebola in 2014-15, and the Zika virus in 2015-16 suggest similar operational difficulties ...

78 FR 44329 - Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

... regulations previously reported. ADDRESSES: Acting Assistant Administrator for Office of Internal Controls and... Internal Controls and Management Systems. National Aeronautics and Space Administration--Proposed Rule... amendments include updates to organizational information, use of the term ``disability'' in lieu of the term...

Notification: FY 2018 CSB Management Challenges and Internal Control Weaknesses

EPA Pesticide Factsheets

December 26, 2017. The OIG is beginning work to update for fiscal year 2018 its list of proposed key management challenges and internal control weaknesses confronting the U.S. Chemical Safety and Hazard Investigation Board (CSB).

76 FR 55869 - Notice of Funding Availability: Inviting Applications for the McGovern-Dole International Food...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... Applications for the McGovern-Dole International Food for Education and Child Nutrition Program; Correction... Federal Register on July 28, 2011, inviting proposals for the McGovern-Dole International Food for... eligibility requirements, makes minor changes to the application and review process, and provides updates to...

76 FR 63658 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; ASTM International

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-13

... Production Act of 1993; ASTM International Notice is hereby given that, on August 31, 2011, pursuant to.... (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with the..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between May...

75 FR 11196 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM International

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-10

... Production Act of 1993--ASTM International Notice is hereby given that, on February 16, 2010, pursuant to.... (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with the..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between May...

77 FR 1085 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM International

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-09

... Production Act of 1993--ASTM International Notice is hereby given that, on December 5, 2011, pursuant to.... (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with the..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between...

75 FR 65657 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM International

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... Production Act of 1993--ASTM International Notice is hereby given that, on September 23, 2010, pursuant to.... (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with the..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between May...

Practical Skills in International Business: Training Needs for Workforce Competence by Minnesota Companies

ERIC Educational Resources Information Center

Prestwich, Roger; Ho-Kim, Thu-Mai

2009-01-01

Companies doing business internationally face the competitive challenges of a constantly changing operational environment. Employees need to update their international knowledge, skills, and abilities (KSA) frequently by attending training programs. A survey of Minnesota firms indicate that almost all companies are willing to cover the time and…

Detection of Earthquake-Induced Damage in a Framed Structure Using a Finite Element Model Updating Procedure

PubMed Central

Kim, Seung-Nam; Park, Taewon; Lee, Sang-Hyun

2014-01-01

Damage of a 5-story framed structure was identified from two types of measured data, which are frequency response functions (FRF) and natural frequencies, using a finite element (FE) model updating procedure. In this study, a procedure to determine the appropriate weightings for different groups of observations was proposed. In addition, a modified frame element which included rotational springs was used to construct the FE model for updating to represent concentrated damage at the member ends (a formulation for plastic hinges in framed structures subjected to strong earthquakes). The results of the model updating and subsequent damage detection when the rotational springs (RS model) were used were compared with those obtained using the conventional frame elements (FS model). Comparisons indicated that the RS model gave more accurate results than the FS model. That is, the errors in the natural frequencies of the updated models were smaller, and the identified damage showed clearer distinctions between damaged and undamaged members and was more consistent with observed damage. PMID:24574888

Streaming parallel GPU acceleration of large-scale filter-based spiking neural networks.

PubMed

Slażyński, Leszek; Bohte, Sander

2012-01-01

The arrival of graphics processing (GPU) cards suitable for massively parallel computing promises affordable large-scale neural network simulation previously only available at supercomputing facilities. While the raw numbers suggest that GPUs may outperform CPUs by at least an order of magnitude, the challenge is to develop fine-grained parallel algorithms to fully exploit the particulars of GPUs. Computation in a neural network is inherently parallel and thus a natural match for GPU architectures: given inputs, the internal state for each neuron can be updated in parallel. We show that for filter-based spiking neurons, like the Spike Response Model, the additive nature of membrane potential dynamics enables additional update parallelism. This also reduces the accumulation of numerical errors when using single precision computation, the native precision of GPUs. We further show that optimizing simulation algorithms and data structures to the GPU's architecture has a large pay-off: for example, matching iterative neural updating to the memory architecture of the GPU speeds up this simulation step by a factor of three to five. With such optimizations, we can simulate in better-than-realtime plausible spiking neural networks of up to 50 000 neurons, processing over 35 million spiking events per second.

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during KSC Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Updated atomic weights: Time to review our table

USGS Publications Warehouse

Coplen, Tyler B.; Meyers, Fabienne; Holden, Norman E.

2016-01-01

Despite common belief, atomic weights are not necessarily constants of nature. Scientists’ ability to measure these values is regularly improving, so one would expect that the accuracy of these values should be improving with time. It is the task of the IUPAC (International Union of Pure and Applied Chemistry) Commission on Isotopic Abundances and Atomic Weights (CIAAW) to regularly review atomic-weight determinations and release updated values.According to an evaluation published in Pure and Applied Chemistry [1], even the most simplified table abridged to four significant digits needs to be updated for the elements selenium and molybdenum. According to the most recent 2015 release of "Atomic Weights of the Elements" [2], another update is needed for ytterbium.

Anger, Hostility, Internalizing Negative Emotions, and Intimate Partner Violence Perpetration: A Meta-Analytic Review

PubMed Central

Birkley, Erica; Eckhardt, Christopher I.

2015-01-01

Prior reviews have identified elevated trait anger as a risk factor for intimate partner violence (IPV) perpetration. Given that 10 years have passed since the last comprehensive review of this literature, we provide an updated meta-analytic review examining associations among anger, hostility, internalizing negative emotions, and IPV for male and female perpetrators. One hundred and five effect sizes from 64 independent samples (61 studies) were included for analysis. IPV perpetration was moderately associated with the constructs of anger, hostility, and internalizing negative emotions. This association appeared stronger for those who perpetrated moderate to severe IPV compared to those who perpetrated low to moderate IPV, and did not vary across perpetrator sex, measurement method, relationship type, or perpetrator population. Implications and limitations of findings were reviewed in the context of theoretical models of IPV, and future directions for empirical and clinical endeavors were proposed. PMID:25752947

Anger, hostility, internalizing negative emotions, and intimate partner violence perpetration: A meta-analytic review.

PubMed

Birkley, Erica L; Eckhardt, Christopher I

2015-04-01

Prior reviews have identified elevated trait anger as a risk factor for intimate partner violence (IPV) perpetration. Given that 10 years have passed since the last comprehensive review of this literature, we provide an updated meta-analytic review examining associations among anger, hostility, internalizing negative emotions, and IPV for male and female perpetrators. One hundred and five effect sizes from 64 independent samples (61 studies) were included for analysis. IPV perpetration was moderately associated with the constructs of anger, hostility, and internalizing negative emotions. This association appeared stronger for those who perpetrated moderate to severe IPV compared to those who perpetrated low to moderate IPV, and did not vary across perpetrator sex, measurement method, relationship type, or perpetrator population. Implications and limitations of findings were reviewed in the context of theoretical models of IPV, and future directions for empirical and clinical endeavors were proposed. Copyright © 2015 Elsevier Ltd. All rights reserved.

Harvesting NASA's Common Metadata Repository (CMR)

NASA Technical Reports Server (NTRS)

Shum, Dana; Durbin, Chris; Norton, James; Mitchell, Andrew

2017-01-01

As part of NASA's Earth Observing System Data and Information System (EOSDIS), the Common Metadata Repository (CMR) stores metadata for over 30,000 datasets from both NASA and international providers along with over 300M granules. This metadata enables sub-second discovery and facilitates data access. While the CMR offers a robust temporal, spatial and keyword search functionality to the general public and international community, it is sometimes more desirable for international partners to harvest the CMR metadata and merge the CMR metadata into a partner's existing metadata repository. This poster will focus on best practices to follow when harvesting CMR metadata to ensure that any changes made to the CMR can also be updated in a partner's own repository. Additionally, since each partner has distinct metadata formats they are able to consume, the best practices will also include guidance on retrieving the metadata in the desired metadata format using CMR's Unified Metadata Model translation software.

Harvesting NASA's Common Metadata Repository

NASA Astrophysics Data System (ADS)

Shum, D.; Mitchell, A. E.; Durbin, C.; Norton, J.

2017-12-01

As part of NASA's Earth Observing System Data and Information System (EOSDIS), the Common Metadata Repository (CMR) stores metadata for over 30,000 datasets from both NASA and international providers along with over 300M granules. This metadata enables sub-second discovery and facilitates data access. While the CMR offers a robust temporal, spatial and keyword search functionality to the general public and international community, it is sometimes more desirable for international partners to harvest the CMR metadata and merge the CMR metadata into a partner's existing metadata repository. This poster will focus on best practices to follow when harvesting CMR metadata to ensure that any changes made to the CMR can also be updated in a partner's own repository. Additionally, since each partner has distinct metadata formats they are able to consume, the best practices will also include guidance on retrieving the metadata in the desired metadata format using CMR's Unified Metadata Model translation software.

Development and Psychometric Analysis of a Nurses’ Attitudes and Skills Safety Scale: Initial Results

PubMed Central

Armstrong, Gail E.; Dietrich, Mary; Norman, Linda; Barnsteiner, Jane; Mion, Lorraine

2016-01-01

Health care organizations have incorporated updated safety principles in the analysis of errors and in norms and standards. Yet no research exists that assesses bedside nurses’ perceived skills or attitudes toward updated safety concepts. The aims of this study were to develop a scale assessing nurses’ perceived skills and attitudes toward updated safety concepts, determine content validity, and examine internal consistency of the scale and subscales. Understanding nurses’ perceived skills and attitudes about safety concepts can be used in targeting strategies to enhance their safety practices. PMID:27479518

Development and Psychometric Analysis of a Nurses' Attitudes and Skills Safety Scale: Initial Results.

PubMed

Armstrong, Gail E; Dietrich, Mary; Norman, Linda; Barnsteiner, Jane; Mion, Lorraine

Health care organizations have incorporated updated safety principles in the analysis of errors and in norms and standards. Yet no research exists that assesses bedside nurses' perceived skills or attitudes toward updated safety concepts. The aims of this study were to develop a scale assessing nurses' perceived skills and attitudes toward updated safety concepts, determine content validity, and examine internal consistency of the scale and subscales. Understanding nurses' perceived skills and attitudes about safety concepts can be used in targeting strategies to enhance their safety practices.

A Data-Driven Framework for Incorporating New Tools for ...

EPA Pesticide Factsheets

This talk was given during the “Exposure-Based Toxicity Testing” session at the annual meeting of the International Society for Exposure Science. It provided an update on the state of the science and tools that may be employed in risk-based prioritization efforts. It outlined knowledge gained from the data provided using these high-throughput tools to assess chemical bioactivity and to predict chemical exposures and also identified future needs. It provided an opportunity to showcase ongoing research efforts within the National Exposure Research Laboratory and the National Center for Computational Toxicology within the Office of Research and Development to an international audience. The National Exposure Research Laboratory (NERL) Computational Exposure Division (CED) develops and evaluates data, decision-support tools, and models to be applied to media-specific or receptor-specific problem areas. CED uses modeling-based approaches to characterize exposures, evaluate fate and transport, and support environmental diagnostics/forensics with input from multiple data sources. It also develops media- and receptor-specific models, process models, and decision support tools for use both within and outside of EPA.

Model updating strategy for structures with localised nonlinearities using frequency response measurements

NASA Astrophysics Data System (ADS)

Wang, Xing; Hill, Thomas L.; Neild, Simon A.; Shaw, Alexander D.; Haddad Khodaparast, Hamed; Friswell, Michael I.

2018-02-01

This paper proposes a model updating strategy for localised nonlinear structures. It utilises an initial finite-element (FE) model of the structure and primary harmonic response data taken from low and high amplitude excitations. The underlying linear part of the FE model is first updated using low-amplitude test data with established techniques. Then, using this linear FE model, the nonlinear elements are localised, characterised, and quantified with primary harmonic response data measured under stepped-sine or swept-sine excitations. Finally, the resulting model is validated by comparing the analytical predictions with both the measured responses used in the updating and with additional test data. The proposed strategy is applied to a clamped beam with a nonlinear mechanism and good agreements between the analytical predictions and measured responses are achieved. Discussions on issues of damping estimation and dealing with data from amplitude-varying force input in the updating process are also provided.

Utilizing Flight Data to Update Aeroelastic Stability Estimates

NASA Technical Reports Server (NTRS)

Lind, Rick; Brenner, Marty

1997-01-01

Stability analysis of high performance aircraft must account for errors in the system model. A method for computing flutter margins that incorporates flight data has been developed using robust stability theory. This paper considers applying this method to update flutter margins during a post-flight or on-line analysis. Areas of modeling uncertainty that arise when using flight data with this method are investigated. The amount of conservatism in the resulting flutter margins depends on the flight data sets used to update the model. Post-flight updates of flutter margins for an F/A-18 are presented along with a simulation of on-line updates during a flight test.

Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Final Report, Version 2)

EPA Science Inventory

EPA's announced the availability of the final report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Version 2). This update furthered land change modeling by providing nationwide housing developmen...

Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee.

PubMed

Rossini, P M; Burke, D; Chen, R; Cohen, L G; Daskalakis, Z; Di Iorio, R; Di Lazzaro, V; Ferreri, F; Fitzgerald, P B; George, M S; Hallett, M; Lefaucheur, J P; Langguth, B; Matsumoto, H; Miniussi, C; Nitsche, M A; Pascual-Leone, A; Paulus, W; Rossi, S; Rothwell, J C; Siebner, H R; Ugawa, Y; Walsh, V; Ziemann, U

2015-06-01

These guidelines provide an up-date of previous IFCN report on "Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application" (Rossini et al., 1994). A new Committee, composed of international experts, some of whom were in the panel of the 1994 "Report", was selected to produce a current state-of-the-art review of non-invasive stimulation both for clinical application and research in neuroscience. Since 1994, the international scientific community has seen a rapid increase in non-invasive brain stimulation in studying cognition, brain-behavior relationship and pathophysiology of various neurologic and psychiatric disorders. New paradigms of stimulation and new techniques have been developed. Furthermore, a large number of studies and clinical trials have demonstrated potential therapeutic applications of non-invasive brain stimulation, especially for TMS. Recent guidelines can be found in the literature covering specific aspects of non-invasive brain stimulation, such as safety (Rossi et al., 2009), methodology (Groppa et al., 2012) and therapeutic applications (Lefaucheur et al., 2014). This up-dated review covers theoretical, physiological and practical aspects of non-invasive stimulation of brain, spinal cord, nerve roots and peripheral nerves in the light of more updated knowledge, and include some recent extensions and developments. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

International Resource Book for Libraries Serving Disadvantaged Persons: 2001-2008. An Update to the International Resource Book for Libraries Serving Disadvantaged Persons: 1931-2001

ERIC Educational Resources Information Center

Locke, Joanne; Panella, Nancy M.

2010-01-01

In 2001, the Libraries Serving Disadvantaged Persons (LSDP) Section of the International Federation of Library Associations and Institutions (IFLA), published the "International Resource Book for Libraries Serving Disadvantaged Persons." This publication is a seventy year retrospective which chronicles the history of the Section from 1931 to 2001.…

Application of Artificial Intelligence for Bridge Deterioration Model.

PubMed

Chen, Zhang; Wu, Yangyang; Li, Li; Sun, Lijun

2015-01-01

The deterministic bridge deterioration model updating problem is well established in bridge management, while the traditional methods and approaches for this problem require manual intervention. An artificial-intelligence-based approach was presented to self-updated parameters of the bridge deterioration model in this paper. When new information and data are collected, a posterior distribution was constructed to describe the integrated result of historical information and the new gained information according to Bayesian theorem, which was used to update model parameters. This AI-based approach is applied to the case of updating parameters of bridge deterioration model, which is the data collected from bridges of 12 districts in Shanghai from 2004 to 2013, and the results showed that it is an accurate, effective, and satisfactory approach to deal with the problem of the parameter updating without manual intervention.

Application of Artificial Intelligence for Bridge Deterioration Model

PubMed Central

Chen, Zhang; Wu, Yangyang; Sun, Lijun

2015-01-01

The deterministic bridge deterioration model updating problem is well established in bridge management, while the traditional methods and approaches for this problem require manual intervention. An artificial-intelligence-based approach was presented to self-updated parameters of the bridge deterioration model in this paper. When new information and data are collected, a posterior distribution was constructed to describe the integrated result of historical information and the new gained information according to Bayesian theorem, which was used to update model parameters. This AI-based approach is applied to the case of updating parameters of bridge deterioration model, which is the data collected from bridges of 12 districts in Shanghai from 2004 to 2013, and the results showed that it is an accurate, effective, and satisfactory approach to deal with the problem of the parameter updating without manual intervention. PMID:26601121

EVALUATED NUCLEAR STRUCTURE DATA FILE AND RELATED PRODUCTS.

DOE Office of Scientific and Technical Information (OSTI.GOV)

TULI,J.K.

The Evaluated Nuclear Structure Data File (ENSDF) is a leading resource for the experimental nuclear data. It is maintained and distributed by the National Nuclear Data Center, Brookhaven National Laboratory. The file is mainly contributed to by an international network of evaluators under the auspice of the International Atomic Energy Agency. The ENSDF is updated, generally by mass number, i.e., evaluating together all isobars for a given mass number. If, however, experimental activity in an isobaric chain is limited to a particular nuclide then only that nuclide is updated. The evaluations are published in the journal Nuclear Data Sheets, Academicmore » Press, a division of Elsevier.« less

InterLymph hierarchical classification of lymphoid neoplasms for epidemiologic research based on the WHO classification (2008): update and future directions

PubMed Central

Morton, Lindsay M.; Linet, Martha S.; Clarke, Christina A.; Kadin, Marshall E.; Vajdic, Claire M.; Monnereau, Alain; Maynadié, Marc; Chiu, Brian C.-H.; Marcos-Gragera, Rafael; Costantini, Adele Seniori; Cerhan, James R.; Weisenburger, Dennis D.

2010-01-01

After publication of the updated World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues in 2008, the Pathology Working Group of the International Lymphoma Epidemiology Consortium (InterLymph) now presents an update of the hierarchical classification of lymphoid neoplasms for epidemiologic research based on the 2001 WHO classification, which we published in 2007. The updated hierarchical classification incorporates all of the major and provisional entities in the 2008 WHO classification, including newly defined entities based on age, site, certain infections, and molecular characteristics, as well as borderline categories, early and “in situ” lesions, disorders with limited capacity for clinical progression, lesions without current International Classification of Diseases for Oncology, 3rd Edition codes, and immunodeficiency-associated lymphoproliferative disorders. WHO subtypes are defined in hierarchical groupings, with newly defined groups for small B-cell lymphomas with plasmacytic differentiation and for primary cutaneous T-cell lymphomas. We suggest approaches for applying the hierarchical classification in various epidemiologic settings, including strategies for dealing with multiple coexisting lymphoma subtypes in one patient, and cases with incomplete pathologic information. The pathology materials useful for state-of-the-art epidemiology studies are also discussed. We encourage epidemiologists to adopt the updated InterLymph hierarchical classification, which incorporates the most recent WHO entities while demonstrating their relationship to older classifications. PMID:20699439

InterLymph hierarchical classification of lymphoid neoplasms for epidemiologic research based on the WHO classification (2008): update and future directions.

PubMed

Turner, Jennifer J; Morton, Lindsay M; Linet, Martha S; Clarke, Christina A; Kadin, Marshall E; Vajdic, Claire M; Monnereau, Alain; Maynadié, Marc; Chiu, Brian C-H; Marcos-Gragera, Rafael; Costantini, Adele Seniori; Cerhan, James R; Weisenburger, Dennis D

2010-11-18

After publication of the updated World Health Organization (WHO) classification of tumors of hematopoietic and lymphoid tissues in 2008, the Pathology Working Group of the International Lymphoma Epidemiology Consortium (InterLymph) now presents an update of the hierarchical classification of lymphoid neoplasms for epidemiologic research based on the 2001 WHO classification, which we published in 2007. The updated hierarchical classification incorporates all of the major and provisional entities in the 2008 WHO classification, including newly defined entities based on age, site, certain infections, and molecular characteristics, as well as borderline categories, early and "in situ" lesions, disorders with limited capacity for clinical progression, lesions without current International Classification of Diseases for Oncology, 3rd Edition codes, and immunodeficiency-associated lymphoproliferative disorders. WHO subtypes are defined in hierarchical groupings, with newly defined groups for small B-cell lymphomas with plasmacytic differentiation and for primary cutaneous T-cell lymphomas. We suggest approaches for applying the hierarchical classification in various epidemiologic settings, including strategies for dealing with multiple coexisting lymphoma subtypes in one patient, and cases with incomplete pathologic information. The pathology materials useful for state-of-the-art epidemiology studies are also discussed. We encourage epidemiologists to adopt the updated InterLymph hierarchical classification, which incorporates the most recent WHO entities while demonstrating their relationship to older classifications.

Overview and Evaluation of the Community Multiscale Air ...

EPA Pesticide Factsheets

The Community Multiscale Air Quality (CMAQ) model is a state-of-the-science air quality model that simulates the emission, transport and fate of numerous air pollutants, including ozone and particulate matter. The Computational Exposure Division (CED) of the U.S. Environmental Protection Agency develops the CMAQ model and periodically releases new versions of the model that include bug fixes and various other improvements to the modeling system. In late 2016 or early 2017, CMAQ version 5.2 will be released. This new version of CMAQ will contain important updates from the current CMAQv5.1 modeling system, along with several instrumented versions of the model (e.g. decoupled direct method and sulfur tracking). Some specific model updates include the implementation of a new wind-blown dust treatment in CMAQv5.2, a significant improvement over the treatment in v5.1 which can severely overestimate wind-blown dust under certain conditions. Several other major updates to the modeling system include an update to the calculation of aerosols; implementation of full halogen chemistry (CMAQv5.1 contains a partial implementation of halogen chemistry); the new carbon bond 6 (CB6) chemical mechanism; updates to cloud model in CMAQ; and a new lightning assimilation scheme for the WRF model which significant improves the placement and timing of convective precipitation in the WRF precipitation fields. Numerous other updates to the modeling system will also be available in v5.2.

SHM-Based Probabilistic Fatigue Life Prediction for Bridges Based on FE Model Updating

PubMed Central

Lee, Young-Joo; Cho, Soojin

2016-01-01

Fatigue life prediction for a bridge should be based on the current condition of the bridge, and various sources of uncertainty, such as material properties, anticipated vehicle loads and environmental conditions, make the prediction very challenging. This paper presents a new approach for probabilistic fatigue life prediction for bridges using finite element (FE) model updating based on structural health monitoring (SHM) data. Recently, various types of SHM systems have been used to monitor and evaluate the long-term structural performance of bridges. For example, SHM data can be used to estimate the degradation of an in-service bridge, which makes it possible to update the initial FE model. The proposed method consists of three steps: (1) identifying the modal properties of a bridge, such as mode shapes and natural frequencies, based on the ambient vibration under passing vehicles; (2) updating the structural parameters of an initial FE model using the identified modal properties; and (3) predicting the probabilistic fatigue life using the updated FE model. The proposed method is demonstrated by application to a numerical model of a bridge, and the impact of FE model updating on the bridge fatigue life is discussed. PMID:26950125

Normal response function method for mass and stiffness matrix updating using complex FRFs

NASA Astrophysics Data System (ADS)

Pradhan, S.; Modak, S. V.

2012-10-01

Quite often a structural dynamic finite element model is required to be updated so as to accurately predict the dynamic characteristics like natural frequencies and the mode shapes. Since in many situations undamped natural frequencies and mode shapes need to be predicted, it has generally been the practice in these situations to seek updating of only mass and stiffness matrix so as to obtain a reliable prediction model. Updating using frequency response functions (FRFs) has been one of the widely used approaches for updating, including updating of mass and stiffness matrices. However, the problem with FRF based methods, for updating mass and stiffness matrices, is that these methods are based on use of complex FRFs. Use of complex FRFs to update mass and stiffness matrices is not theoretically correct as complex FRFs are not only affected by these two matrices but also by the damping matrix. Therefore, in situations where updating of only mass and stiffness matrices using FRFs is required, the use of complex FRFs based updating formulation is not fully justified and would lead to inaccurate updated models. This paper addresses this difficulty and proposes an improved FRF based finite element model updating procedure using the concept of normal FRFs. The proposed method is a modified version of the existing response function method that is based on the complex FRFs. The effectiveness of the proposed method is validated through a numerical study of a simple but representative beam structure. The effect of coordinate incompleteness and robustness of method under presence of noise is investigated. The results of updating obtained by the improved method are compared with the existing response function method. The performance of the two approaches is compared for cases of light, medium and heavily damped structures. It is found that the proposed improved method is effective in updating of mass and stiffness matrices in all the cases of complete and incomplete data and with all levels and types of damping.

Proceedings of the NASTRAN (Tradename) Users’ Colloquium (8th) Held in Greenbelt, Maryland on 30-31 October 1979

DTIC Science & Technology

1980-05-01

36 wing were replaced by a six foot extension and winglet on the 28/29 wing (see Figures 1 & 2). The outward appearance of the 28/29 wing in the...in NASA TMX-3428 (Ref. 1). This model was later updated in the outboard section with the six foot extension and winglet attachment structure. Sizing...incorporated to provide stiffness and an internal lo3d path for forces developed by the winglet , since the winglet was mounted very near the trailing

A pressure relaxation closure model for one-dimensional, two-material Lagrangian hydrodynamics based on the Riemann problem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamm, James R; Shashkov, Mikhail J

2009-01-01

Despite decades of development, Lagrangian hydrodynamics of strengthfree materials presents numerous open issues, even in one dimension. We focus on the problem of closing a system of equations for a two-material cell under the assumption of a single velocity model. There are several existing models and approaches, each possessing different levels of fidelity to the underlying physics and each exhibiting unique features in the computed solutions. We consider the case in which the change in heat in the constituent materials in the mixed cell is assumed equal. An instantaneous pressure equilibration model for a mixed cell can be cast asmore » four equations in four unknowns, comprised of the updated values of the specific internal energy and the specific volume for each of the two materials in the mixed cell. The unique contribution of our approach is a physics-inspired, geometry-based model in which the updated values of the sub-cell, relaxing-toward-equilibrium constituent pressures are related to a local Riemann problem through an optimization principle. This approach couples the modeling problem of assigning sub-cell pressures to the physics associated with the local, dynamic evolution. We package our approach in the framework of a standard predictor-corrector time integration scheme. We evaluate our model using idealized, two material problems using either ideal-gas or stiffened-gas equations of state and compare these results to those computed with the method of Tipton and with corresponding pure-material calculations.« less

Survey geometry and the internal consistency of recent cosmic shear measurements

NASA Astrophysics Data System (ADS)

Troxel, M. A.; Krause, E.; Chang, C.; Eifler, T. F.; Friedrich, O.; Gruen, D.; MacCrann, N.; Chen, A.; Davis, C.; DeRose, J.; Dodelson, S.; Gatti, M.; Hoyle, B.; Huterer, D.; Jarvis, M.; Lacasa, F.; Lemos, P.; Peiris, H. V.; Prat, J.; Samuroff, S.; Sánchez, C.; Sheldon, E.; Vielzeuf, P.; Wang, M.; Zuntz, J.; Lahav, O.; Abdalla, F. B.; Allam, S.; Annis, J.; Avila, S.; Bertin, E.; Brooks, D.; Burke, D. L.; Rosell, A. Carnero; Kind, M. Carrasco; Carretero, J.; Crocce, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; De Vicente, J.; Diehl, H. T.; Doel, P.; Evrard, A. E.; Flaugher, B.; Fosalba, P.; Frieman, J.; García-Bellido, J.; Gaztanaga, E.; Gerdes, D. W.; Gruendl, R. A.; Gschwend, J.; Gutierrez, G.; Hartley, W. G.; Hollowood, D. L.; Honscheid, K.; James, D. J.; Kirk, D.; Kuehn, K.; Kuropatkin, N.; Li, T. S.; Lima, M.; March, M.; Menanteau, F.; Miquel, R.; Mohr, J. J.; Ogando, R. L. C.; Plazas, A. A.; Roodman, A.; Sanchez, E.; Scarpine, V.; Schindler, R.; Sevilla-Noarbe, I.; Smith, M.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Thomas, D.; Walker, A. R.; Wechsler, R. H.

2018-06-01

We explore the impact of an update to the typical approximation for the shape noise term in the analytic covariance matrix for cosmic shear experiments that assumes the absence of survey boundary and mask effects. We present an exact expression for the number of galaxy pairs in this term based on the survey mask, which leads to more than a factor of three increase in the shape noise on the largest measured scales for the Kilo-Degree Survey (KIDS-450) real-space cosmic shear data. We compare the result of this analytic expression to several alternative methods for measuring the shape noise from the data and find excellent agreement. This update to the covariance resolves any internal model tension evidenced by the previously large cosmological best-fit χ2 for the KiDS-450 cosmic shear data. The best-fit χ2 is reduced from 161 to 121 for 118 degrees of freedom. We also apply a correction to how the multiplicative shear calibration uncertainty is included in the covariance. This change shifts the inferred amplitude of the correlation function to higher values. We find that this improves agreement of the KiDS-450 cosmic shear results with Dark Energy Survey Year 1 and Planck results.

77 FR 62211 - Senior Executive Services (SES) Performance Review Board: Update

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-12

... AGENCY FOR INTERNATIONAL DEVELOPMENT Senior Executive Services (SES) Performance Review Board... International Development, Office of Inspector General's Senior Executive Service Performance Review Board... Performance Review Boards. The board shall review and evaluate the initial appraisal of each USAID OIG senior...

14 CFR 293.10 - Exemption.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Secretary for Aviation and International Affairs will, by notice, issue and periodically update a list... REGULATIONS INTERNATIONAL PASSENGER TRANSPORTATION Exemption From Filing Tariffs § 293.10 Exemption. (a) Air... carriers of the Parties; (ii) Whether the country's Government has disapproved or deterred U.S. carrier...

14 CFR 293.10 - Exemption.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Secretary for Aviation and International Affairs will, by notice, issue and periodically update a list... REGULATIONS INTERNATIONAL PASSENGER TRANSPORTATION Exemption From Filing Tariffs § 293.10 Exemption. (a) Air... carriers of the Parties; (ii) Whether the country's Government has disapproved or deterred U.S. carrier...

14 CFR 293.10 - Exemption.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Secretary for Aviation and International Affairs will, by notice, issue and periodically update a list... REGULATIONS INTERNATIONAL PASSENGER TRANSPORTATION Exemption From Filing Tariffs § 293.10 Exemption. (a) Air... carriers of the Parties; (ii) Whether the country's Government has disapproved or deterred U.S. carrier...

14 CFR 293.10 - Exemption.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Secretary for Aviation and International Affairs will, by notice, issue and periodically update a list... REGULATIONS INTERNATIONAL PASSENGER TRANSPORTATION Exemption From Filing Tariffs § 293.10 Exemption. (a) Air... carriers of the Parties; (ii) Whether the country's Government has disapproved or deterred U.S. carrier...

Progress report to the International Fruit Tree Association

USDA-ARS?s Scientific Manuscript database

This report provides an update on several projects that are fostered by the International Fruit Tree Association which covers some aspects of rootstock development, performance in the orchard and to address nursery industry needs. The report highlights results from graft union strength experiments,...

Space-to-Ground: Night Launch: 03/23/2018

NASA Image and Video Library

2018-03-22

Three more crewmembers are on their way to the International Space Station...the crew readies for a spacewalk...and can an astronaut's movement affect the station's orbit? NASA's Space to Ground is your weekly update on what's happening aboard the International Space Station.

Comparison of two optimization algorithms for fuzzy finite element model updating for damage detection in a wind turbine blade

NASA Astrophysics Data System (ADS)

Turnbull, Heather; Omenzetter, Piotr

2018-03-01

vDifficulties associated with current health monitoring and inspection practices combined with harsh, often remote, operational environments of wind turbines highlight the requirement for a non-destructive evaluation system capable of remotely monitoring the current structural state of turbine blades. This research adopted a physics based structural health monitoring methodology through calibration of a finite element model using inverse techniques. A 2.36m blade from a 5kW turbine was used as an experimental specimen, with operational modal analysis techniques utilised to realize the modal properties of the system. Modelling the experimental responses as fuzzy numbers using the sub-level technique, uncertainty in the response parameters was propagated back through the model and into the updating parameters. Initially, experimental responses of the blade were obtained, with a numerical model of the blade created and updated. Deterministic updating was carried out through formulation and minimisation of a deterministic objective function using both firefly algorithm and virus optimisation algorithm. Uncertainty in experimental responses were modelled using triangular membership functions, allowing membership functions of updating parameters (Young's modulus and shear modulus) to be obtained. Firefly algorithm and virus optimisation algorithm were again utilised, however, this time in the solution of fuzzy objective functions. This enabled uncertainty associated with updating parameters to be quantified. Varying damage location and severity was simulated experimentally through addition of small masses to the structure intended to cause a structural alteration. A damaged model was created, modelling four variable magnitude nonstructural masses at predefined points and updated to provide a deterministic damage prediction and information in relation to the parameters uncertainty via fuzzy updating.

Comparative Study of foF2 Measurements with IRI-2007 Model Predictions During Extended Solar Minimum

NASA Technical Reports Server (NTRS)

Zakharenkova, I. E.; Krankowski, A.; Bilitza, D.; Cherniak, Iu.V.; Shagimuratov, I.I.; Sieradzki, R.

2013-01-01

The unusually deep and extended solar minimum of cycle 2324 made it very difficult to predict the solar indices 1 or 2 years into the future. Most of the predictions were proven wrong by the actual observed indices. IRI gets its solar, magnetic, and ionospheric indices from an indices file that is updated twice a year. In recent years, due to the unusual solar minimum, predictions had to be corrected downward with every new indices update. In this paper we analyse how much the uncertainties in the predictability of solar activity indices affect the IRI outcome and how the IRI values calculated with predicted and observed indices compared to the actual measurements.Monthly median values of F2 layer critical frequency (foF2) derived from the ionosonde measurements at the mid-latitude ionospheric station Juliusruh were compared with the International Reference Ionosphere (IRI-2007) model predictions. The analysis found that IRIprovides reliable results that compare well with actual measurements, when the definite (observed and adjusted) indices of solar activityare used, while IRI values based on earlier predictions of these indices noticeably overestimated the measurements during the solar minimum.One of the principal objectives of this paper is to direct attention of IRI users to update their solar activity indices files regularly.Use of an older index file can lead to serious IRI overestimations of F-region electron density during the recent extended solar minimum.

Numerical modeling and model updating for smart laminated structures with viscoelastic damping

NASA Astrophysics Data System (ADS)

Lu, Jun; Zhan, Zhenfei; Liu, Xu; Wang, Pan

2018-07-01

This paper presents a numerical modeling method combined with model updating techniques for the analysis of smart laminated structures with viscoelastic damping. Starting with finite element formulation, the dynamics model with piezoelectric actuators is derived based on the constitutive law of the multilayer plate structure. The frequency-dependent characteristics of the viscoelastic core are represented utilizing the anelastic displacement fields (ADF) parametric model in the time domain. The analytical model is validated experimentally and used to analyze the influencing factors of kinetic parameters under parametric variations. Emphasis is placed upon model updating for smart laminated structures to improve the accuracy of the numerical model. Key design variables are selected through the smoothing spline ANOVA statistical technique to mitigate the computational cost. This updating strategy not only corrects the natural frequencies but also improves the accuracy of damping prediction. The effectiveness of the approach is examined through an application problem of a smart laminated plate. It is shown that a good consistency can be achieved between updated results and measurements. The proposed method is computationally efficient.

Adapting to change: The role of the right hemisphere in mental model building and updating.

PubMed

Filipowicz, Alex; Anderson, Britt; Danckert, James

2016-09-01

We recently proposed that the right hemisphere plays a crucial role in the processes underlying mental model building and updating. Here, we review the evidence we and others have garnered to support this novel account of right hemisphere function. We begin by presenting evidence from patient work that suggests a critical role for the right hemisphere in the ability to learn from the statistics in the environment (model building) and adapt to environmental change (model updating). We then provide a review of neuroimaging research that highlights a network of brain regions involved in mental model updating. Next, we outline specific roles for particular regions within the network such that the anterior insula is purported to maintain the current model of the environment, the medial prefrontal cortex determines when to explore new or alternative models, and the inferior parietal lobule represents salient and surprising information with respect to the current model. We conclude by proposing some future directions that address some of the outstanding questions in the field of mental model building and updating. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

The 2006 Cape Canaveral Air Force Station Range Reference Atmosphere Model Validation Study and Sensitivity Analysis to the National Aeronautics and Space Administration's Space Shuttle

NASA Technical Reports Server (NTRS)

Burns, Lee; Merry, Carl; Decker, Ryan; Harrington, Brian

2008-01-01

The 2006 Cape Canaveral Air Force Station (CCAFS) Range Reference Atmosphere (RRA) is a statistical model summarizing the wind and thermodynamic atmospheric variability from surface to 70 kin. Launches of the National Aeronautics and Space Administration's (NASA) Space Shuttle from Kennedy Space Center utilize CCAFS RRA data to evaluate environmental constraints on various aspects of the vehicle during ascent. An update to the CCAFS RRA was recently completed. As part of the update, a validation study on the 2006 version was conducted as well as a comparison analysis of the 2006 version to the existing CCAFS RRA database version 1983. Assessments to the Space Shuttle vehicle ascent profile characteristics were performed to determine impacts of the updated model to the vehicle performance. Details on the model updates and the vehicle sensitivity analyses with the update model are presented.

Artificial Boundary Conditions for Finite Element Model Update and Damage Detection

DTIC Science & Technology

2017-03-01

BOUNDARY CONDITIONS FOR FINITE ELEMENT MODEL UPDATE AND DAMAGE DETECTION by Emmanouil Damanakis March 2017 Thesis Advisor: Joshua H. Gordis...REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE ARTIFICIAL BOUNDARY CONDITIONS FOR FINITE ELEMENT MODEL UPDATE AND DAMAGE DETECTION...release. Distribution is unlimited. 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) In structural engineering, a finite element model is often

An Investigation Into the Effects of Frequency Response Function Estimators on Model Updating

NASA Astrophysics Data System (ADS)

Ratcliffe, M. J.; Lieven, N. A. J.

1999-03-01

Model updating is a very active research field, in which significant effort has been invested in recent years. Model updating methodologies are invariably successful when used on noise-free simulated data, but tend to be unpredictable when presented with real experimental data that are—unavoidably—corrupted with uncorrelated noise content. In the development and validation of model-updating strategies, a random zero-mean Gaussian variable is added to simulated test data to tax the updating routines more fully. This paper proposes a more sophisticated model for experimental measurement noise, and this is used in conjunction with several different frequency response function estimators, from the classical H1and H2to more refined estimators that purport to be unbiased. Finite-element model case studies, in conjunction with a genuine experimental test, suggest that the proposed noise model is a more realistic representation of experimental noise phenomena. The choice of estimator is shown to have a significant influence on the viability of the FRF sensitivity method. These test cases find that the use of the H2estimator for model updating purposes is contraindicated, and that there is no advantage to be gained by using the sophisticated estimators over the classical H1estimator.

An updated Lagrangian particle hydrodynamics (ULPH) for Newtonian fluids

NASA Astrophysics Data System (ADS)

Tu, Qingsong; Li, Shaofan

2017-11-01

In this work, we have developed an updated Lagrangian particle hydrodynamics (ULPH) for Newtonian fluid. Unlike the smoothed particle hydrodynamics, the non-local particle hydrodynamics formulation proposed here is consistent and convergence. Unlike the state-based peridynamics, the discrete particle dynamics proposed here has no internal material bond between particles, and it is not formulated with respect to initial or a fixed referential configuration. In specific, we have shown that (1) the non-local update Lagrangian particle hydrodynamics formulation converges to the conventional local fluid mechanics formulation; (2) the non-local updated Lagrangian particle hydrodynamics can capture arbitrary flow discontinuities without any changes in the formulation, and (3) the proposed non-local particle hydrodynamics is computationally efficient and robust.

Adaptation of clinical prediction models for application in local settings.

PubMed

Kappen, Teus H; Vergouwe, Yvonne; van Klei, Wilton A; van Wolfswinkel, Leo; Kalkman, Cor J; Moons, Karel G M

2012-01-01

When planning to use a validated prediction model in new patients, adequate performance is not guaranteed. For example, changes in clinical practice over time or a different case mix than the original validation population may result in inaccurate risk predictions. To demonstrate how clinical information can direct updating a prediction model and development of a strategy for handling missing predictor values in clinical practice. A previously derived and validated prediction model for postoperative nausea and vomiting was updated using a data set of 1847 patients. The update consisted of 1) changing the definition of an existing predictor, 2) reestimating the regression coefficient of a predictor, and 3) adding a new predictor to the model. The updated model was then validated in a new series of 3822 patients. Furthermore, several imputation models were considered to handle real-time missing values, so that possible missing predictor values could be anticipated during actual model use. Differences in clinical practice between our local population and the original derivation population guided the update strategy of the prediction model. The predictive accuracy of the updated model was better (c statistic, 0.68; calibration slope, 1.0) than the original model (c statistic, 0.62; calibration slope, 0.57). Inclusion of logistical variables in the imputation models, besides observed patient characteristics, contributed to a strategy to deal with missing predictor values at the time of risk calculation. Extensive knowledge of local, clinical processes provides crucial information to guide the process of adapting a prediction model to new clinical practices.

A review and update of the Virginia Department of Transportation cash flow forecasting model.

DOT National Transportation Integrated Search

1996-01-01

This report details the research done to review and update components of the VDOT cash flow forecasting model. Specifically, the study updated the monthly factors submodel used to predict payments on construction contracts. For the other submodel rev...

Guidance for updating clinical practice guidelines: a systematic review of methodological handbooks.

PubMed

Vernooij, Robin W M; Sanabria, Andrea Juliana; Solà, Ivan; Alonso-Coello, Pablo; Martínez García, Laura

2014-01-02

Updating clinical practice guidelines (CPGs) is a crucial process for maintaining the validity of recommendations. Methodological handbooks should provide guidance on both developing and updating CPGs. However, little is known about the updating guidance provided by these handbooks. We conducted a systematic review to identify and describe the updating guidance provided by CPG methodological handbooks and included handbooks that provide updating guidance for CPGs. We searched in the Guidelines International Network library, US National Guidelines Clearinghouse and MEDLINE (PubMed) from 1966 to September 2013. Two authors independently selected the handbooks and extracted the data. We used descriptive statistics to analyze the extracted data and conducted a narrative synthesis. We included 35 handbooks. Most handbooks (97.1%) focus mainly on developing CPGs, including variable degrees of information about updating. Guidance on identifying new evidence and the methodology of assessing the need for an update is described in 11 (31.4%) and eight handbooks (22.8%), respectively. The period of time between two updates is described in 25 handbooks (71.4%), two to three years being the most frequent (40.0%). The majority of handbooks do not provide guidance for the literature search, evidence selection, assessment, synthesis, and external review of the updating process. Guidance for updating CPGs is poorly described in methodological handbooks. This guidance should be more rigorous and explicit. This could lead to a more optimal updating process, and, ultimately to valid trustworthy guidelines.

General Separations Area (GSA) Groundwater Flow Model Update: Hydrostratigraphic Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bagwell, L.; Bennett, P.; Flach, G.

2017-02-21

This document describes the assembly, selection, and interpretation of hydrostratigraphic data for input to an updated groundwater flow model for the General Separations Area (GSA; Figure 1) at the Department of Energy’s (DOE) Savannah River Site (SRS). This report is one of several discrete but interrelated tasks that support development of an updated groundwater model (Bagwell and Flach, 2016).

Update in Outpatient General Internal Medicine: Practice-Changing Evidence Published in 2015.

PubMed

Szostek, Jason H; Wieland, Mark L; Post, Jason A; Sundsted, Karna K; Mauck, Karen F

2016-08-01

Identifying new practice-changing articles is challenging. To determine the 2015 practice-changing articles most relevant to outpatient general internal medicine, 3 internists independently reviewed the titles and abstracts of original articles, synopses of single studies and syntheses, and databases of syntheses. For original articles, internal medicine journals with the 7 highest impact factors were reviewed: New England Journal of Medicine, Lancet, Journal of the American Medical Association (JAMA), British Medical Journal, Public Library of Science Medicine, Annals of Internal Medicine, and JAMA Internal Medicine. For synopses of single studies and syntheses, collections in American College of Physicians Journal Club, Journal Watch, and Evidence-Based Medicine were reviewed. For databases of synthesis, Evidence Updates and the Cochrane Library were reviewed. More than 100 articles were identified. Criteria for inclusion were as follows: clinical relevance, potential for practice change, and strength of evidence. Clusters of important articles around one topic were considered as a single-candidate series. The 5 authors used a modified Delphi method to reach consensus on inclusion of 7 topics for in-depth appraisal. Copyright © 2016 Elsevier Inc. All rights reserved.

Update in Outpatient General Internal Medicine: Practice-Changing Evidence Published in 2017.

PubMed

Wieland, Mark L; Szostek, Jason H; Wingo, Majken T; Post, Jason A; Mauck, Karen F

2018-02-26

Clinicians are challenged to identify new practice-changing articles in the medical literature. To identify the practice-changing articles published in 2017 most relevant to outpatient general internal medicine, 5 internists reviewed the following sources: 1) titles and abstracts from internal medicine journals with the 7 highest impact factors, including New England Journal of Medicine, Lancet, Journal of the American Medical Association, British Medical Journal, Public Library of Science Medicine, Annals of Internal Medicine, and JAMA Internal Medicine; 2) synopses and syntheses of individual studies, including collections in the American College of Physicians Journal Club, Journal Watch, and Evidence-Based Medicine; 3) databases of synthesis, including Evidence Updates and the Cochrane Library. Inclusion criteria were perceived clinical relevance to outpatient general medicine, potential for practice change, and strength of evidence. This process yielded 140 articles. Clusters of important articles around one topic were considered as a single-candidate series. A modified Delphi method was utilized by the 5 authors to reach consensus on 7 topics to highlight and appraise from the 2017 literature. Copyright © 2018 Elsevier Inc. All rights reserved.

Dynamic analysis of I cross beam section dissimilar plate joined by TIG welding

NASA Astrophysics Data System (ADS)

Sani, M. S. M.; Nazri, N. A.; Rani, M. N. Abdul; Yunus, M. A.

2018-04-01

In this paper, finite element (FE) joint modelling technique for prediction of dynamic properties of sheet metal jointed by tungsten inert gas (TTG) will be presented. I cross section dissimilar flat plate with different series of aluminium alloy; AA7075 and AA6061 joined by TTG are used. In order to find the most optimum set of TTG welding dissimilar plate, the finite element model with three types of joint modelling were engaged in this study; bar element (CBAR), beam element and spot weld element connector (CWELD). Experimental modal analysis (EMA) was carried out by impact hammer excitation on the dissimilar plates that welding by TTG method. Modal properties of FE model with joints were compared and validated with model testing. CWELD element was chosen to represent weld model for TTG joints due to its accurate prediction of mode shapes and contains an updating parameter for weld modelling compare to other weld modelling. Model updating was performed to improve correlation between EMA and FEA and before proceeds to updating, sensitivity analysis was done to select the most sensitive updating parameter. After perform model updating, average percentage of error of the natural frequencies for CWELD model is improved significantly.

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update.

PubMed

Johnson, J A; Caudle, K E; Gong, L; Whirl-Carrillo, M; Stein, C M; Scott, S A; Lee, M T; Gage, B F; Kimmel, S E; Perera, M A; Anderson, J L; Pirmohamed, M; Klein, T E; Limdi, N A; Cavallari, L H; Wadelius, M

2017-09-01

This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing. Evidence from the published literature is presented for CYP2C9, VKORC1, CYP4F2, and rs12777823 genotype-guided warfarin dosing to achieve a target international normalized ratio of 2-3 when clinical genotype results are available. In addition, this updated guideline incorporates recommendations for adult and pediatric patients that are specific to continental ancestry. © 2017 American Society for Clinical Pharmacology and Therapeutics.

Guidelines for stem cell science and clinical translation.

PubMed

Pandya, Sunil K

2016-01-01

The International Society for Stem Cell Research has released its updated guidelines for stem cell research in order to provide "assurance that stem cell research is conducted with scientific and ethical integrity and that new therapies are evidence-based." The guidelines were updated by a Guidelines Update Task Force consisting of twenty-five scientists, ethicists and experts in health care policy from nine countries. The chairpersons of this task force are Jonathan Kimmelman, George Daley and Insoo Hyun. There is no representative from India; the only person of Indian origin on it, Mahendra Rao, represents The New York Stem Cell Foundation.

Test and analysis procedures for updating math models of Space Shuttle payloads

NASA Technical Reports Server (NTRS)

Craig, Roy R., Jr.

1991-01-01

Over the next decade or more, the Space Shuttle will continue to be the primary transportation system for delivering payloads to Earth orbit. Although a number of payloads have already been successfully carried by the Space Shuttle in the payload bay of the Orbiter vehicle, there continues to be a need for evaluation of the procedures used for verifying and updating the math models of the payloads. The verified payload math models is combined with an Orbiter math model for the coupled-loads analysis, which is required before any payload can fly. Several test procedures were employed for obtaining data for use in verifying payload math models and for carrying out the updating of the payload math models. Research was directed at the evaluation of test/update procedures for use in the verification of Space Shuttle payload math models. The following research tasks are summarized: (1) a study of free-interface test procedures; (2) a literature survey and evaluation of model update procedures; and (3) the design and construction of a laboratory payload simulator.

Build-up Approach to Updating the Mock Quiet Spike(TradeMark) Beam Model

NASA Technical Reports Server (NTRS)

Herrera, Claudia Y.; Pak, Chan-gi

2007-01-01

A crucial part of aircraft design is ensuring that the required margin for flutter is satisfied. A trustworthy flutter analysis, which begins by possessing an accurate dynamics model, is necessary for this task. Traditionally, a model was updated manually by fine tuning specific stiffness parameters until the analytical results matched test data. This is a time consuming iterative process. NASA Dryden Flight Research Center has developed a mode matching code to execute this process in a more efficient manner. Recently, this code was implemented in the F-15B/Quiet Spike(TradeMark) (Gulfstream Aerospace Corporation, Savannah, Georgia) model update. A build-up approach requiring several ground vibration test configurations and a series of model updates was implemented in order to determine the connection stiffness between aircraft and test article. The mode matching code successfully updated various models for the F-15B/Quiet Spike(TradeMark) project to within 1 percent error in frequency and the modal assurance criteria values ranged from 88.51-99.42 percent.

Build-up Approach to Updating the Mock Quiet Spike(TM)Beam Model

NASA Technical Reports Server (NTRS)

Herrera, Claudia Y.; Pak, Chan-gi

2007-01-01

A crucial part of aircraft design is ensuring that the required margin for flutter is satisfied. A trustworthy flutter analysis, which begins by possessing an accurate dynamics model, is necessary for this task. Traditionally, a model was updated manually by fine tuning specific stiffness parameters until the analytical results matched test data. This is a time consuming iterative process. The NASA Dryden Flight Research Center has developed a mode matching code to execute this process in a more efficient manner. Recently, this code was implemented in the F-15B/Quiet Spike (Gulfstream Aerospace Corporation, Savannah, Georgia) model update. A build-up approach requiring several ground vibration test configurations and a series of model updates was implemented to determine the connection stiffness between aircraft and test article. The mode matching code successfully updated various models for the F-15B/Quiet Spike project to within 1 percent error in frequency and the modal assurance criteria values ranged from 88.51-99.42 percent.

Updates to the Demographic and Spatial Allocation Models to ...

EPA Pesticide Factsheets

EPA announced the availability of the draft report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) for a 30-day public comment period. The ICLUS version 2 (v2) modeling tool furthered land change modeling by providing nationwide housing development scenarios up to 2100. ICLUS V2 includes updated population and land use data sets and addressing limitations identified in ICLUS v1 in both the migration and spatial allocation models. The companion user guide describes the development of ICLUS v2 and the updates that were made to the original data sets and the demographic and spatial allocation models. [2017 UPDATE] Get the latest version of ICLUS and stay up-to-date by signing up to the ICLUS mailing list. The GIS tool enables users to run SERGoM with the population projections developed for the ICLUS project and allows users to modify the spatial allocation housing density across the landscape.

BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface

PubMed Central

Lee, A J; Cunningham, A P; Kuchenbaecker, K B; Mavaddat, N; Easton, D F; Antoniou, A C

2014-01-01

Background: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) is a risk prediction model that is used to compute probabilities of carrying mutations in the high-risk breast and ovarian cancer susceptibility genes BRCA1 and BRCA2, and to estimate the future risks of developing breast or ovarian cancer. In this paper, we describe updates to the BOADICEA model that extend its capabilities, make it easier to use in a clinical setting and yield more accurate predictions. Methods: We describe: (1) updates to the statistical model to include cancer incidences from multiple populations; (2) updates to the distributions of tumour pathology characteristics using new data on BRCA1 and BRCA2 mutation carriers and women with breast cancer from the general population; (3) improvements to the computational efficiency of the algorithm so that risk calculations now run substantially faster; and (4) updates to the model's web interface to accommodate these new features and to make it easier to use in a clinical setting. Results: We present results derived using the updated model, and demonstrate that the changes have a significant impact on risk predictions. Conclusion: All updates have been implemented in a new version of the BOADICEA web interface that is now available for general use: http://ccge.medschl.cam.ac.uk/boadicea/. PMID:24346285

Ionosonde-based indices for improved representation of solar cycle variation in the International Reference Ionosphere model

NASA Astrophysics Data System (ADS)

Brown, Steven; Bilitza, Dieter; Yiǧit, Erdal

2018-06-01

A new monthly ionospheric index, IGNS, is presented to improve the representation of the solar cycle variation of the ionospheric F2 peak plasma frequency, foF2. IGNS is calculated using a methodology similar to the construction of the "global effective sunspot number", IG, given by Liu et al. (1983) but selects ionosonde observations based on hemispheres. We incorporated the updated index into the International Reference Ionosphere (IRI) model and compared the foF2 model predictions with global ionospheric observations. We also investigated the influence of the underlying foF2 model on the IG index. IRI has two options for foF2 specification, the CCIR-66 and URSI-88 foF2 models. For the first time, we have calculated IG using URSI-88 and assessed the impact on model predictions. Through a retrospective model-data comparison, results show that the inclusion of the new monthly IGNS index in place of the current 12-month smoothed IG index reduce the foF2 model prediction errors by nearly a factor of two. These results apply to both day-time and nightime predictions. This is due to an overall improved prediction of foF2 seasonal and solar cycle variations in the different hemispheres.

Prescription Opioids

MedlinePlus

... also often involve benzodiazepines. Benzodiazepines are central nervous system depressants used to sedate, ... Health, National Prescription Audit (NPATM). Cited in internal document: Preliminary Update on ...

Pneumonia

MedlinePlus

... 2015 Updated by: Denis Hadjiliadis, MD, MHS, Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Internal ...

TEMPUS: Simulating personnel and tasks in a 3-D environment

NASA Technical Reports Server (NTRS)

Badler, N. I.; Korein, J. D.

1985-01-01

The latest TEMPUS installation occurred in March, 1985. Another update is slated for early June, 1985. An updated User's Manual is in preparation and will be delivered approximately mid-June, 1985. NASA JSC has full source code listings and internal documentation for installed software. NASA JSC staff has received instruction in the use of TEMPUS. Telephone consultations have augmented on-site instruction.

Report of Accomplishments under the Airport Improvement Program.

DTIC Science & Technology

1982-09-30

Acquire snow removal equipment; conduct City of Portland feasibility study. Portland International (PRIMARY) Presque Isle 01 $ 15,840 Airport Master Plan...update to terminal City of Presque Isle area plan). Northern Maine Regional (PRIMARY) Presque Isle 02 $ 118,869 Rehabilitate terminal access road...City of Presque Isle Northern Maine Regional (PRIMARY) Rockland 01 $ 40,252 Airport Master Plan (update). Knox County Knox County Regional (COMMERCIAL

Eleventh Annual Report of Accomplishments Under the Airport Improvement Program

DTIC Science & Technology

1992-01-01

552,860 INSTALL SECURITY SYSTEM PORTLAND INTERNATIONAL JETPORT (PRIMARY) 25 $255, 195 CONSTRUCT ACCESS ROAD PRESQUE ISLE 09 $988,548 CONSTRUCT AIRCRAFT...TAXIWAYS; INSTALL VISUAL APPROACH AIDS PENNSYLVANIA COMMONWEALTH OF PENNSYLVANIA S7 $89,050 CONDUCT STATE SYSTEM PLAN UPDATE (SYSTEM PLAN) DELAWARE...VALLEY REGION RA $195,030 CONDUCT STATE SYSTEM PLAN UPDATE (SYSTEM PLAN) SOUTHWESTERN PENNSYLVANIA REGION RA $310,950 CONDUCT REGIONAL SYSTEM PLAN

Steps towards Improving GNSS Systematic Errors and Biases

NASA Astrophysics Data System (ADS)

Herring, T.; Moore, M.

2017-12-01

Four general areas of analysis method improvements, three related to data analysis models and the fourth to calibration methods, have been recommended at the recent unified analysis workshop (UAW) and we discuss aspects of these areas for improvement. The gravity fields used in the GNSS orbit integrations should be updated to match modern fields to make them consistent with the fields being used by the other IAG services. The update would include the static part of the field and a time variable component. The force models associated with radiation forces are the most uncertain and modeling of these forces can be made more consistent with the exchange of attitude information. The international GNSS service (IGS) will develop an attitude format and make attitude information available so that analysis centers can validate their models. The IGS has noted the appearance of the GPS draconitic period and harmonics of this period in time series of various geodetic products (e.g., positions and Earth orientation parameters). An updated short-period (diurnal and semidiurnal) model is needed and a method to determine the best model developed. The final area, not directly related to analysis models, is the recommendation that site dependent calibration of GNSS antennas are needed since these have a direct effect on the ITRF realization and position offsets when antennas are changed. Evaluation of the effects of the use of antenna specific phase center models will be investigated for those sites where these values are available without disturbing an existing antenna installation. Potential development of an in-situ antenna calibration system is strongly encouraged. In-situ calibration would be deployed at core sites where GNSS sites are tied to other geodetic systems. With recent expansion of the number of GPS satellites transmitting unencrypted codes on the GPS L2 frequency and the availability of software GNSS receivers in-situ calibration between an existing installation and a movable directional antenna is now more likely to generate accurate results than earlier analog switching systems. With all of these improvements, there is the expectation that there will be better agreement between the space geodetic methods thus allowing more definitive assessment and modeling of the Earth's time variable shape and gravity field.

Dissociable effects of surprise and model update in parietal and anterior cingulate cortex

PubMed Central

O’Reilly, Jill X.; Schüffelgen, Urs; Cuell, Steven F.; Behrens, Timothy E. J.; Mars, Rogier B.; Rushworth, Matthew F. S.

2013-01-01

Brains use predictive models to facilitate the processing of expected stimuli or planned actions. Under a predictive model, surprising (low probability) stimuli or actions necessitate the immediate reallocation of processing resources, but they can also signal the need to update the underlying predictive model to reflect changes in the environment. Surprise and updating are often correlated in experimental paradigms but are, in fact, distinct constructs that can be formally defined as the Shannon information (IS) and Kullback–Leibler divergence (DKL) associated with an observation. In a saccadic planning task, we observed that distinct behaviors and brain regions are associated with surprise/IS and updating/DKL. Although surprise/IS was associated with behavioral reprogramming as indexed by slower reaction times, as well as with activity in the posterior parietal cortex [human lateral intraparietal area (LIP)], the anterior cingulate cortex (ACC) was specifically activated during updating of the predictive model (DKL). A second saccade-sensitive region in the inferior posterior parietal cortex (human 7a), which has connections to both LIP and ACC, was activated by surprise and modulated by updating. Pupillometry revealed a further dissociation between surprise and updating with an early positive effect of surprise and late negative effect of updating on pupil area. These results give a computational account of the roles of the ACC and two parietal saccade regions, LIP and 7a, by which their involvement in diverse tasks can be understood mechanistically. The dissociation of functional roles between regions within the reorienting/reprogramming network may also inform models of neurological phenomena, such as extinction and Balint syndrome, and neglect. PMID:23986499

2017 Updates: Earth Gravitational Model 2020

NASA Astrophysics Data System (ADS)

Barnes, D. E.; Holmes, S. A.; Ingalls, S.; Beale, J.; Presicci, M. R.; Minter, C.

2017-12-01

The National Geospatial-Intelligence Agency [NGA], in conjunction with its U.S. and international partners, has begun preliminary work on its next Earth Gravitational Model, to replace EGM2008. The new `Earth Gravitational Model 2020' [EGM2020] has an expected public release date of 2020, and will retain the same harmonic basis and resolution as EGM2008. As such, EGM2020 will be essentially an ellipsoidal harmonic model up to degree (n) and order (m) 2159, but will be released as a spherical harmonic model to degree 2190 and order 2159. EGM2020 will benefit from new data sources and procedures. Updated satellite gravity information from the GOCE and GRACE mission, will better support the lower harmonics, globally. Multiple new acquisitions (terrestrial, airborne and shipborne) of gravimetric data over specific geographical areas (Antarctica, Greenland …), will provide improved global coverage and resolution over the land, as well as for coastal and some ocean areas. Ongoing accumulation of satellite altimetry data as well as improvements in the treatment of this data, will better define the marine gravity field, most notably in polar and near-coastal regions. NGA and partners are evaluating different approaches for optimally combining the new GOCE/GRACE satellite gravity models with the terrestrial data. These include the latest methods employing a full covariance adjustment. NGA is also working to assess systematically the quality of its entire gravimetry database, towards correcting biases and other egregious errors. Public release number 15-564

Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops.

PubMed

Phan, Andy; Mailey, Katherine; Saeki, Jessica; Gu, Xiaobo; Schroeder, Susan J

2017-05-01

Accurate thermodynamic parameters improve RNA structure predictions and thus accelerate understanding of RNA function and the identification of RNA drug binding sites. Many viral RNA structures, such as internal ribosome entry sites, have internal loops and bulges that are potential drug target sites. Current models used to predict internal loops are biased toward small, symmetric purine loops, and thus poorly predict asymmetric, pyrimidine-rich loops with >6 nucleotides (nt) that occur frequently in viral RNA. This article presents new thermodynamic data for 40 pyrimidine loops, many of which can form UU or protonated CC base pairs. Uracil and protonated cytosine base pairs stabilize asymmetric internal loops. Accurate prediction rules are presented that account for all thermodynamic measurements of RNA asymmetric internal loops. New loop initiation terms for loops with >6 nt are presented that do not follow previous assumptions that increasing asymmetry destabilizes loops. Since the last 2004 update, 126 new loops with asymmetry or sizes greater than 2 × 2 have been measured. These new measurements significantly deepen and diversify the thermodynamic database for RNA. These results will help better predict internal loops that are larger, pyrimidine-rich, and occur within viral structures such as internal ribosome entry sites. © 2017 Phan et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

International News Flows in the Post-Cold War World: Mapping the News and the News Producers.

ERIC Educational Resources Information Center

Sreberny-Mohammadi, Annabelle

1995-01-01

Reviews the global political environment, major global news providers, and technologies of global news production. Argues for a multinational comparative mapping of international news representation in the 1990s. Outlines a major international venture to update and elaborate the 1979 UNESCO/IAMCR study of foreign news in the media of 29 countries,…

The Organisation for Economic Co-Operation and Development's International Early Learning Study: What Happened Next

ERIC Educational Resources Information Center

Moss, Peter; Urban, Mathias

2017-01-01

In this article, the authors provide an update on what has happened over recent months with the Organisation for Economic Co-operation and Development's proposal for an International Early Learning Study, and review responses to the proposed International Early Learning Study, including the concerns that have been raised about this new venture in…

Chemical transport model simulations of organic aerosol in ...

EPA Pesticide Factsheets

Gasoline- and diesel-fueled engines are ubiquitous sources of air pollution in urban environments. They emit both primary particulate matter and precursor gases that react to form secondary particulate matter in the atmosphere. In this work, we updated the organic aerosol module and organic emissions inventory of a three-dimensional chemical transport model, the Community Multiscale Air Quality Model (CMAQ), using recent, experimentally derived inputs and parameterizations for mobile sources. The updated model included a revised volatile organic compound (VOC) speciation for mobile sources and secondary organic aerosol (SOA) formation from unspeciated intermediate volatility organic compounds (IVOCs). The updated model was used to simulate air quality in southern California during May and June 2010, when the California Research at the Nexus of Air Quality and Climate Change (CalNex) study was conducted. Compared to the Traditional version of CMAQ, which is commonly used for regulatory applications, the updated model did not significantly alter the predicted organic aerosol (OA) mass concentrations but did substantially improve predictions of OA sources and composition (e.g., POA–SOA split), as well as ambient IVOC concentrations. The updated model, despite substantial differences in emissions and chemistry, performed similar to a recently released research version of CMAQ (Woody et al., 2016) that did not include the updated VOC and IVOC emissions and SOA data

Insights on multivariate updates of physical and biogeochemical ocean variables using an Ensemble Kalman Filter and an idealized model of upwelling

NASA Astrophysics Data System (ADS)

Yu, Liuqian; Fennel, Katja; Bertino, Laurent; Gharamti, Mohamad El; Thompson, Keith R.

2018-06-01

Effective data assimilation methods for incorporating observations into marine biogeochemical models are required to improve hindcasts, nowcasts and forecasts of the ocean's biogeochemical state. Recent assimilation efforts have shown that updating model physics alone can degrade biogeochemical fields while only updating biogeochemical variables may not improve a model's predictive skill when the physical fields are inaccurate. Here we systematically investigate whether multivariate updates of physical and biogeochemical model states are superior to only updating either physical or biogeochemical variables. We conducted a series of twin experiments in an idealized ocean channel that experiences wind-driven upwelling. The forecast model was forced with biased wind stress and perturbed biogeochemical model parameters compared to the model run representing the "truth". Taking advantage of the multivariate nature of the deterministic Ensemble Kalman Filter (DEnKF), we assimilated different combinations of synthetic physical (sea surface height, sea surface temperature and temperature profiles) and biogeochemical (surface chlorophyll and nitrate profiles) observations. We show that when biogeochemical and physical properties are highly correlated (e.g., thermocline and nutricline), multivariate updates of both are essential for improving model skill and can be accomplished by assimilating either physical (e.g., temperature profiles) or biogeochemical (e.g., nutrient profiles) observations. In our idealized domain, the improvement is largely due to a better representation of nutrient upwelling, which results in a more accurate nutrient input into the euphotic zone. In contrast, assimilating surface chlorophyll improves the model state only slightly, because surface chlorophyll contains little information about the vertical density structure. We also show that a degradation of the correlation between observed subsurface temperature and nutrient fields, which has been an issue in several previous assimilation studies, can be reduced by multivariate updates of physical and biogeochemical fields.

Model updating in flexible-link multibody systems

NASA Astrophysics Data System (ADS)

Belotti, R.; Caneva, G.; Palomba, I.; Richiedei, D.; Trevisani, A.

2016-09-01

The dynamic response of flexible-link multibody systems (FLMSs) can be predicted through nonlinear models based on finite elements, to describe the coupling between rigid- body and elastic behaviour. Their accuracy should be as high as possible to synthesize controllers and observers. Model updating based on experimental measurements is hence necessary. By taking advantage of the experimental modal analysis, this work proposes a model updating procedure for FLMSs and applies it experimentally to a planar robot. Indeed, several peculiarities of the model of FLMS should be carefully tackled. On the one hand, nonlinear models of a FLMS should be linearized about static equilibrium configurations. On the other, the experimental mode shapes should be corrected to be consistent with the elastic displacements represented in the model, which are defined with respect to a fictitious moving reference (the equivalent rigid link system). Then, since rotational degrees of freedom are also represented in the model, interpolation of the experimental data should be performed to match the model displacement vector. Model updating has been finally cast as an optimization problem in the presence of bounds on the feasible values, by also adopting methods to improve the numerical conditioning and to compute meaningful updated inertial and elastic parameters.

Stellar Parameters for Trappist-1

NASA Astrophysics Data System (ADS)

Van Grootel, Valérie; Fernandes, Catarina S.; Gillon, Michael; Jehin, Emmanuel; Manfroid, Jean; Scuflaire, Richard; Burgasser, Adam J.; Barkaoui, Khalid; Benkhaldoun, Zouhair; Burdanov, Artem; Delrez, Laetitia; Demory, Brice-Olivier; de Wit, Julien; Queloz, Didier; Triaud, Amaury H. M. J.

2018-01-01

TRAPPIST-1 is an ultracool dwarf star transited by seven Earth-sized planets, for which thorough characterization of atmospheric properties, surface conditions encompassing habitability, and internal compositions is possible with current and next-generation telescopes. Accurate modeling of the star is essential to achieve this goal. We aim to obtain updated stellar parameters for TRAPPIST-1 based on new measurements and evolutionary models, compared to those used in discovery studies. We present a new measurement for the parallax of TRAPPIST-1, 82.4 ± 0.8 mas, based on 188 epochs of observations with the TRAPPIST and Liverpool Telescopes from 2013 to 2016. This revised parallax yields an updated luminosity of {L}* =(5.22+/- 0.19)× {10}-4 {L}ȯ , which is very close to the previous estimate but almost two times more precise. We next present an updated estimate for TRAPPIST-1 stellar mass, based on two approaches: mass from stellar evolution modeling, and empirical mass derived from dynamical masses of equivalently classified ultracool dwarfs in astrometric binaries. We combine them using a Monte-Carlo approach to derive a semi-empirical estimate for the mass of TRAPPIST-1. We also derive estimate for the radius by combining this mass with stellar density inferred from transits, as well as an estimate for the effective temperature from our revised luminosity and radius. Our final results are {M}* =0.089+/- 0.006 {M}ȯ , {R}* =0.121+/- 0.003 {R}ȯ , and {T}{eff} = 2516 ± 41 K. Considering the degree to which the TRAPPIST-1 system will be scrutinized in coming years, these revised and more precise stellar parameters should be considered when assessing the properties of TRAPPIST-1 planets.

Fairbairn's Theory of Change.

PubMed

Celani, David P

2016-06-01

Fairbairn's unique structural theory with its three pairs of selves and objects has proven to be a highly usable and practical model of the human psyche, yet it has remained a minor player in the world of psychoanalysis. There are a number of factors that account for its lack of popularity, foremost among them the timing of the model's introduction to the analytic community. Fairbairn's four successive papers that described his metapsychology (1940, 1941, 1943, and 1944) were published just after Freud's death, when his theory was the dominant model of psychoanalysis. Additionally, Fairbairn's model was incomplete, used unfamiliar terminology, and, in its singularity, forced the analyst to abandon drive theory, the heart of Freud's metapsychology. This paper will examine and update Fairbairn's unique model of change-from the outset of pathology that begins with attachment to bad objects, to their metamorphosis into internal structures and finally to techniques of treatment that reduce their influence on the patients' internal world. The treatment section carefully follows Fairbairn's metapsychology, and focuses first on the analyst becoming a good object in the eyes of the patient, then unearthing bad object memories in a safe and compassionate interpersonal environment, engaging the patient's substructures in a manner that does not intensify preexisting internal templates, and finally aiding the patient in resuming his or her stalled emotional development. This exegesis of Fairbairn original model, along with recent modifications that have been made to it, demonstrates the consistency, clear focus, and utility of this little-known metapsychology.

Investigating the Impact on Modeled Ozone Concentrations Using Meteorological Fields From WRF With and Updated Four-Dimensional Data Assimilation Approach”

EPA Science Inventory

The four-dimensional data assimilation (FDDA) technique in the Weather Research and Forecasting (WRF) meteorological model has recently undergone an important update from the original version. Previous evaluation results have demonstrated that the updated FDDA approach in WRF pr...

Aqua/Aura Updated Inclination Adjust Maneuver Performance Prediction Model

NASA Technical Reports Server (NTRS)

Boone, Spencer

2017-01-01

This presentation will discuss the updated Inclination Adjust Maneuver (IAM) performance prediction model that was developed for Aqua and Aura following the 2017 IAM series. This updated model uses statistical regression methods to identify potential long-term trends in maneuver parameters, yielding improved predictions when re-planning past maneuvers. The presentation has been reviewed and approved by Eric Moyer, ESMO Deputy Project Manager.

The Effect of Improved Sub-Daily Earth Rotation Models on Global GPS Data Processing

NASA Astrophysics Data System (ADS)

Yoon, S.; Choi, K. K.

2017-12-01

Throughout the various International GNSS Service (IGS) products, strong periodic signals have been observed around the 14 day period. This signal is clearly visible in all IGS time-series such as those related to orbit ephemerides, Earth rotation parameters (ERP) and ground station coordinates. Recent studies show that errors in the sub-daily Earth rotation models are the main factors that induce such noise. Current IGS orbit processing standards adopted the IERS 2010 convention and its sub-daily Earth rotation model. Since the IERS convention had published, recent advances in the VLBI analysis have made contributions to update the sub-daily Earth rotation models. We have compared several proposed sub-daily Earth rotation models and show the effect of using those models on orbit ephemeris, Earth rotation parameters and ground station coordinates generated by the NGS global GPS data processing strategy.

77 FR 35410 - Fogarty International Center 2013 Strategic Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... needs. The Fogarty International Center supports basic, clinical and applied research and training for U...) is updating its strategic plan. To anticipate and set priorities for global health research and research training, FIC requests input from scientists, the general public, and interested parties. The goal...

STATE-OF-THE-ART PROCEDURES AND EQUIPMENT FOR INTERNAL INSPECTION AND UPGRADING OF UNDERGROUND STORAGE TANKS

EPA Science Inventory

This report supplements the previous State-of-the-Art Procedures and Equipment for Internal Inspection of Underground Storage Tanks published in 1991 by the EPA. The present report updates and provides descriptions of additional tank inspection technologies, specifically, noninva...

Measuring and Benchmarking Technical Efficiency of Public Hospitals in Tianjin, China: A Bootstrap-Data Envelopment Analysis Approach.

PubMed

Li, Hao; Dong, Siping

2015-01-01

China has long been stuck in applying traditional data envelopment analysis (DEA) models to measure technical efficiency of public hospitals without bias correction of efficiency scores. In this article, we have introduced the Bootstrap-DEA approach from the international literature to analyze the technical efficiency of public hospitals in Tianjin (China) and tried to improve the application of this method for benchmarking and inter-organizational learning. It is found that the bias corrected efficiency scores of Bootstrap-DEA differ significantly from those of the traditional Banker, Charnes, and Cooper (BCC) model, which means that Chinese researchers need to update their DEA models for more scientific calculation of hospital efficiency scores. Our research has helped shorten the gap between China and the international world in relative efficiency measurement and improvement of hospitals. It is suggested that Bootstrap-DEA be widely applied into afterward research to measure relative efficiency and productivity of Chinese hospitals so as to better serve for efficiency improvement and related decision making. © The Author(s) 2015.

Support time-dependent transformations for surveying and GIS : current status and upcoming challenges

NASA Astrophysics Data System (ADS)

Mahmoudabadi, H.; Lercier, D.; Vielliard, S.; Mein, N.; Briggs, G.

2016-12-01

The support of time-dependent transformations for surveying and GIS is becoming a critical issue. We need to convert positions from the realizations of the International Terrestrial Reference Frame to any national reference frame. This problem is easy to solve when all of the required information is available. But it becomes really complicated in a worldwide context. We propose an overview of the current ITRF-aligned reference frames and we describe a global solution to support time-dependent transformations between them and the International Terrestrial Reference Frame. We focus on the uncertainties of station velocities used. In a first approximation, we use a global tectonic plate model to calculate point velocities. We show the impact of the velocity model on the coordinate accuracies. Several countries, particularly in active regions, are developing semi-dynamic reference frames. These frames include local displacement models updated regularly and/or after major events (such as earthquakes). Their integration into surveying or GIS applications is an upcoming challenge. We want to encourage the geodetic community to develop and use standard formats.

The influence of an uncertain force environment on reshaping trial-to-trial motor variability.

PubMed

Izawa, Jun; Yoshioka, Toshinori; Osu, Rieko

2014-09-10

Motor memory is updated to generate ideal movements in a novel environment. When the environment changes every trial randomly, how does the brain incorporate this uncertainty into motor memory? To investigate how the brain adapts to an uncertain environment, we considered a reach adaptation protocol where individuals practiced moving in a force field where a noise was injected. After they had adapted, we measured the trial-to-trial variability in the temporal profiles of the produced hand force. We found that the motor variability was significantly magnified by the adaptation to the random force field. Temporal profiles of the motor variance were significantly dissociable between two different types of random force fields experienced. A model-based analysis suggests that the variability is generated by noise in the gains of the internal model. It further suggests that the trial-to-trial motor variability magnified by the adaptation in a random force field is generated by the uncertainty of the internal model formed in the brain as a result of the adaptation.

Valence-Dependent Belief Updating: Computational Validation

PubMed Central

Kuzmanovic, Bojana; Rigoux, Lionel

2017-01-01

People tend to update beliefs about their future outcomes in a valence-dependent way: they are likely to incorporate good news and to neglect bad news. However, belief formation is a complex process which depends not only on motivational factors such as the desire for favorable conclusions, but also on multiple cognitive variables such as prior beliefs, knowledge about personal vulnerabilities and resources, and the size of the probabilities and estimation errors. Thus, we applied computational modeling in order to test for valence-induced biases in updating while formally controlling for relevant cognitive factors. We compared biased and unbiased Bayesian models of belief updating, and specified alternative models based on reinforcement learning. The experiment consisted of 80 trials with 80 different adverse future life events. In each trial, participants estimated the base rate of one of these events and estimated their own risk of experiencing the event before and after being confronted with the actual base rate. Belief updates corresponded to the difference between the two self-risk estimates. Valence-dependent updating was assessed by comparing trials with good news (better-than-expected base rates) with trials with bad news (worse-than-expected base rates). After receiving bad relative to good news, participants' updates were smaller and deviated more strongly from rational Bayesian predictions, indicating a valence-induced bias. Model comparison revealed that the biased (i.e., optimistic) Bayesian model of belief updating better accounted for data than the unbiased (i.e., rational) Bayesian model, confirming that the valence of the new information influenced the amount of updating. Moreover, alternative computational modeling based on reinforcement learning demonstrated higher learning rates for good than for bad news, as well as a moderating role of personal knowledge. Finally, in this specific experimental context, the approach based on reinforcement learning was superior to the Bayesian approach. The computational validation of valence-dependent belief updating represents a novel support for a genuine optimism bias in human belief formation. Moreover, the precise control of relevant cognitive variables justifies the conclusion that the motivation to adopt the most favorable self-referential conclusions biases human judgments. PMID:28706499

Valence-Dependent Belief Updating: Computational Validation.

PubMed

Kuzmanovic, Bojana; Rigoux, Lionel

2017-01-01

People tend to update beliefs about their future outcomes in a valence-dependent way: they are likely to incorporate good news and to neglect bad news. However, belief formation is a complex process which depends not only on motivational factors such as the desire for favorable conclusions, but also on multiple cognitive variables such as prior beliefs, knowledge about personal vulnerabilities and resources, and the size of the probabilities and estimation errors. Thus, we applied computational modeling in order to test for valence-induced biases in updating while formally controlling for relevant cognitive factors. We compared biased and unbiased Bayesian models of belief updating, and specified alternative models based on reinforcement learning. The experiment consisted of 80 trials with 80 different adverse future life events. In each trial, participants estimated the base rate of one of these events and estimated their own risk of experiencing the event before and after being confronted with the actual base rate. Belief updates corresponded to the difference between the two self-risk estimates. Valence-dependent updating was assessed by comparing trials with good news (better-than-expected base rates) with trials with bad news (worse-than-expected base rates). After receiving bad relative to good news, participants' updates were smaller and deviated more strongly from rational Bayesian predictions, indicating a valence-induced bias. Model comparison revealed that the biased (i.e., optimistic) Bayesian model of belief updating better accounted for data than the unbiased (i.e., rational) Bayesian model, confirming that the valence of the new information influenced the amount of updating. Moreover, alternative computational modeling based on reinforcement learning demonstrated higher learning rates for good than for bad news, as well as a moderating role of personal knowledge. Finally, in this specific experimental context, the approach based on reinforcement learning was superior to the Bayesian approach. The computational validation of valence-dependent belief updating represents a novel support for a genuine optimism bias in human belief formation. Moreover, the precise control of relevant cognitive variables justifies the conclusion that the motivation to adopt the most favorable self-referential conclusions biases human judgments.

The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After.

PubMed

Bassi, Claudio; Marchegiani, Giovanni; Dervenis, Christos; Sarr, Micheal; Abu Hilal, Mohammad; Adham, Mustapha; Allen, Peter; Andersson, Roland; Asbun, Horacio J; Besselink, Marc G; Conlon, Kevin; Del Chiaro, Marco; Falconi, Massimo; Fernandez-Cruz, Laureano; Fernandez-Del Castillo, Carlos; Fingerhut, Abe; Friess, Helmut; Gouma, Dirk J; Hackert, Thilo; Izbicki, Jakob; Lillemoe, Keith D; Neoptolemos, John P; Olah, Attila; Schulick, Richard; Shrikhande, Shailesh V; Takada, Tadahiro; Takaori, Kyoichi; Traverso, William; Vollmer, Charles R; Wolfgang, Christopher L; Yeo, Charles J; Salvia, Roberto; Buchler, Marcus

2017-03-01

In 2005, the International Study Group of Pancreatic Fistula developed a definition and grading of postoperative pancreatic fistula that has been accepted universally. Eleven years later, because postoperative pancreatic fistula remains one of the most relevant and harmful complications of pancreatic operation, the International Study Group of Pancreatic Fistula classification has become the gold standard in defining postoperative pancreatic fistula in clinical practice. The aim of the present report is to verify the value of the International Study Group of Pancreatic Fistula definition and grading of postoperative pancreatic fistula and to update the International Study Group of Pancreatic Fistula classification in light of recent evidence that has emerged, as well as to address the lingering controversies about the original definition and grading of postoperative pancreatic fistula. The International Study Group of Pancreatic Fistula reconvened as the International Study Group in Pancreatic Surgery in order to perform a review of the recent literature and consequently to update and revise the grading system of postoperative pancreatic fistula. Based on the literature since 2005 investigating the validity and clinical use of the original International Study Group of Pancreatic Fistula classification, a clinically relevant postoperative pancreatic fistula is now redefined as a drain output of any measurable volume of fluid with an amylase level >3 times the upper limit of institutional normal serum amylase activity, associated with a clinically relevant development/condition related directly to the postoperative pancreatic fistula. Consequently, the former "grade A postoperative pancreatic fistula" is now redefined and called a "biochemical leak," because it has no clinical importance and is no longer referred to a true pancreatic fistula. Postoperative pancreatic fistula grades B and C are confirmed but defined more strictly. In particular, grade B requires a change in the postoperative management; drains are either left in place >3 weeks or repositioned through endoscopic or percutaneous procedures. Grade C postoperative pancreatic fistula refers to those postoperative pancreatic fistula that require reoperation or lead to single or multiple organ failure and/or mortality attributable to the pancreatic fistula. This new definition and grading system of postoperative pancreatic fistula should lead to a more universally consistent evaluation of operative outcomes after pancreatic operation and will allow for a better comparison of techniques used to mitigate the rate and clinical impact of a pancreatic fistula. Use of this updated classification will also allow for more precise comparisons of surgical quality between surgeons and units who perform pancreatic surgery. Copyright © 2016 Elsevier Inc. All rights reserved.

Attentional focus affects how events are segmented and updated in narrative reading.

PubMed

Bailey, Heather R; Kurby, Christopher A; Sargent, Jesse Q; Zacks, Jeffrey M

2017-08-01

Readers generate situation models representing described events, but the nature of these representations may differ depending on the reading goals. We assessed whether instructions to pay attention to different situational dimensions affect how individuals structure their situation models (Exp. 1) and how they update these models when situations change (Exp. 2). In Experiment 1, participants read and segmented narrative texts into events. Some readers were oriented to pay specific attention to characters or space. Sentences containing character or spatial-location changes were perceived as event boundaries-particularly if the reader was oriented to characters or space, respectively. In Experiment 2, participants read narratives and responded to recognition probes throughout the texts. Readers who were oriented to the spatial dimension were more likely to update their situation models at spatial changes; all readers tracked the character dimension. The results from both experiments indicated that attention to individual situational dimensions influences how readers segment and update their situation models. More broadly, the results provide evidence for a global situation model updating mechanism that serves to set up new models at important narrative changes.

Evaluation of the groundwater-flow model for the Ohio River alluvial aquifer near Carrollton, Kentucky, updated to conditions in September 2010

USGS Publications Warehouse

Unthank, Michael D.

2013-01-01

The Ohio River alluvial aquifer near Carrollton, Ky., is an important water resource for the cities of Carrollton and Ghent, as well as for several industries in the area. The groundwater of the aquifer is the primary source of drinking water in the region and a highly valued natural resource that attracts various water-dependent industries because of its quantity and quality. This report evaluates the performance of a numerical model of the groundwater-flow system in the Ohio River alluvial aquifer near Carrollton, Ky., published by the U.S. Geological Survey in 1999. The original model simulated conditions in November 1995 and was updated to simulate groundwater conditions estimated for September 2010. The files from the calibrated steady-state model of November 1995 conditions were imported into MODFLOW-2005 to update the model to conditions in September 2010. The model input files modified as part of this update were the well and recharge files. The design of the updated model and other input files are the same as the original model. The ability of the updated model to match hydrologic conditions for September 2010 was evaluated by comparing water levels measured in wells to those computed by the model. Water-level measurements were available for 48 wells in September 2010. Overall, the updated model underestimated the water levels at 36 of the 48 measured wells. The average difference between measured water levels and model-computed water levels was 3.4 feet and the maximum difference was 10.9 feet. The root-mean-square error of the simulation was 4.45 for all 48 measured water levels. The updated steady-state model could be improved by introducing more accurate and site-specific estimates of selected field parameters, refined model geometry, and additional numerical methods. Collection of field data to better estimate hydraulic parameters, together with continued review of available data and information from area well operators, could provide the model with revised estimates of conductance values for the riverbed and valley wall, hydraulic conductivities for the model layer, and target water levels for future simulations. Additional model layers, a redesigned model grid, and revised boundary conditions could provide a better framework for more accurate simulations. Additional numerical methods would identify possible parameter estimates and determine parameter sensitivities.

The social psychology of seismic hazard adjustment: re-evaluating the international literature

NASA Astrophysics Data System (ADS)

Solberg, C.; Rossetto, T.; Joffe, H.

2010-08-01

The majority of people at risk from earthquakes do little or nothing to reduce their vulnerability. Over the past 40 years social scientists have tried to predict and explain levels of seismic hazard adjustment using models from behavioural sciences such as psychology. The present paper is the first to synthesise the major findings from the international literature on psychological correlates and causes of seismic adjustment at the level of the individual and the household. It starts by reviewing research on seismic risk perception. Next, it looks at norms and normative beliefs, focusing particularly on issues of earthquake protection responsibility and trust between risk stakeholders. It then considers research on attitudes towards seismic adjustment attributes, specifically beliefs about efficacy, control and fate. It concludes that an updated model of seismic adjustment must give the issues of norms, trust, power and identity a more prominent role. These have been only sparsely represented in the social psychological literature to date.

Adherence of preventive oral care products in the Syrian market to evidence-based international recommendations.

PubMed

Habes, D; Mahzia, R; Nakhleh, K; Joury, E

2016-09-25

No study has investigated the availability and adherence of preventive oral care products on the Syrian market to evidence-based international recommendations. Data were collected in 2012, and updated in 2016, in terms of availability, characteristics and adherence to evidence-based international recommendations. Few preventive products adhered to the recommendations. Despite the large decrease in the number of oral care products on the Syrian market, due to the Syrian crisis, nonadherence of some of the available products is still present. A multisectorial approach at a policy level is needed to address such important limitations. The Syrian Ministry of Health should reform regulations for fluoride products to become subject to drug monitoring systems; the Syrian Arab Committee for Measurements and Standards needs to update its standards; and the Syrian General Dental Association should distribute a preventive booklet to dental practitioners.

Preface: International Reference Ionosphere - Progress in Ionospheric Modelling

NASA Technical Reports Server (NTRS)

Bilitza Dieter; Reinisch, Bodo

2010-01-01

The international reference ionosphere (lRI) is the internationally recommended empirical model for the specification of ionospheric parameters supported by the Committee on Space Research (COSPAR) and the International Union of Radio Science (URSI) and recognized by the International Standardization Organization (ISO). IRI is being continually improved by a team of international experts as new data become available and better models are being developed. This issue chronicles the latest phase of model updates as reported during two IRI-related meetings. The first was a special session during the Scientific Assembly of the Committee of Space Research (COSPAR) in Montreal, Canada in July 2008 and the second was an IRI Task Force Activity at the US Air Force Academy in Colorado Springs in May 2009. This work led to several improvements and additions of the model which will be included in the next version, IRI-201O. The issue is divided into three sections focusing on the improvements made in the topside ionosphere, the F-peak, and the lower ionosphere, respectively. This issue would not have been possible without the reviewing efforts of many individuals. Each paper was reviewed by two referees. We thankfully acknowledge the contribution to this issue made by the following reviewers: Jacob Adeniyi, David Altadill, Eduardo Araujo, Feza Arikan, Dieter Bilitza, Jilijana Cander, Bela Fejer, Tamara Gulyaeva, Manuel Hermindez-Pajares, Ivan Kutiev, John MacDougal, Leo McNamara, Bruno Nava, Olivier Obrou, Elijah Oyeyemi, Vadym Paznukhov, Bodo Reinisch, John Retterer, Phil Richards, Gary Sales, J.H. Sastri, Ludger Scherliess, Iwona Stanislavska, Stamir Stankov, Shin-Yi Su, Manlian Zhang, Y ongliang Zhang, and Irina Zakharenkova. We are grateful to Peggy Ann Shea for her final review and guidance as the editor-in-chief for special issues of Advances in Space Research. We thank the authors for their timely submission and their quick response to the reviewer comments and humbly apologize for any delays in the editing process.

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. Attendees mingled and visited various displays, including Ground Systems Development and Operations Program and Education Office displays. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. An attendee talks with engineers Jason Hopkins and Lisa Lutz, at the Ground Systems Development and Operations display. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. Rob Mueller, senior technologist, talks with attendees at the Swamp Works display. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. An attendee talks with Scott Thurston, Kennedy deputy of the spacecraft office at the Commercial Crew Program display. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. Rob Mueller, a senior technologist, talks to an attendee about Kennedy’s Swamp Works Laboratory. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Comparative Performance Evaluation of Rainfall-runoff Models, Six of Black-box Type and One of Conceptual Type, From The Galway Flow Forecasting System (gffs) Package, Applied On Two Irish Catchments

NASA Astrophysics Data System (ADS)

Goswami, M.; O'Connor, K. M.; Shamseldin, A. Y.

The "Galway Real-Time River Flow Forecasting System" (GFFS) is a software pack- age developed at the Department of Engineering Hydrology, of the National University of Ireland, Galway, Ireland. It is based on a selection of lumped black-box and con- ceptual rainfall-runoff models, all developed in Galway, consisting primarily of both the non-parametric (NP) and parametric (P) forms of two black-box-type rainfall- runoff models, namely, the Simple Linear Model (SLM-NP and SLM-P) and the seasonally-based Linear Perturbation Model (LPM-NP and LPM-P), together with the non-parametric wetness-index-based Linearly Varying Gain Factor Model (LVGFM), the black-box Artificial Neural Network (ANN) Model, and the conceptual Soil Mois- ture Accounting and Routing (SMAR) Model. Comprised of the above suite of mod- els, the system enables the user to calibrate each model individually, initially without updating, and it is capable also of producing combined (i.e. consensus) forecasts us- ing the Simple Average Method (SAM), the Weighted Average Method (WAM), or the Artificial Neural Network Method (NNM). The updating of each model output is achieved using one of four different techniques, namely, simple Auto-Regressive (AR) updating, Linear Transfer Function (LTF) updating, Artificial Neural Network updating (NNU), and updating by the Non-linear Auto-Regressive Exogenous-input method (NARXM). The models exhibit a considerable range of variation in degree of complexity of structure, with corresponding degrees of complication in objective func- tion evaluation. Operating in continuous river-flow simulation and updating modes, these models and techniques have been applied to two Irish catchments, namely, the Fergus and the Brosna. A number of performance evaluation criteria have been used to comparatively assess the model discharge forecast efficiency.

Improved Airport Noise Modeling for High Altitudes and Flexible Flight Operations

NASA Technical Reports Server (NTRS)

Forsyth, David W.; Follet, Jesse I.

2006-01-01

The FAA's Integrated Noise Model (INM) is widely used to estimate noise in the vicinity of airports. This study supports the development of standards by which the fleet data in the INM can be updated. A comparison of weather corrections to noise data using INM Spectral Classes is made with the Boeing integrated method. The INM spectral class method is shown to work well, capturing noise level differences due to weather especially at long distances. Two studies conducted at the Denver International Airport are included in the appendices. The two studies adopted different approaches to modeling flight operations at the airport. When compared to the original, year 2000, results, it is apparent that changes made to the INM in terms of modeling processes and databases have resulted in improved agreement between predicted and measured noise levels.

Update of the International Consensus on Palliative Radiotherapy Endpoints for Future Clinical Trials in Bone Metastases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chow, Edward, E-mail: Edward.Chow@sunnybrook.ca; Hoskin, Peter; Mitera, Gunita

2012-04-01

Purpose: To update the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases by surveying international experts regarding previous uncertainties within the 2002 consensus, changes that may be necessary based on practice pattern changes and research findings since that time. Methods and Materials: A two-phase survey was used to determine revisions and new additions to the 2002 consensus. A total of 49 experts from the American Society for Radiation Oncology, the European Society for Therapeutic Radiology and Oncology, the Faculty of Radiation Oncology of the Royal Australian and New Zealand College of Radiologists, and the Canadianmore » Association of Radiation Oncology who are directly involved in the care of patients with bone metastases participated in this survey. Results: Consensus was established in areas involving response definitions, eligibility criteria for future trials, reirradiation, changes in systemic therapy, radiation techniques, parameters at follow-up, and timing of assessments. Conclusion: An outline for trials in bone metastases was updated based on survey and consensus. Investigators leading trials in bone metastases are encouraged to adopt the revised guideline to promote consistent reporting. Areas for future research were identified. It is intended for the consensus to be re-examined in the future on a regular basis.« less

E2C(R2) Periodic Benefit-Risk Evaluation Report and E2C(R2) Periodic Benefit-Risk Evaluation Report--Questions and Answers; International Council for Harmonisation; Guidances for Industry; Availability. Notice.

PubMed

2016-07-19

The Food and Drug Administration (FDA or Agency) is announcing the availability of guidances for industry entitled ``E2C(R2) Periodic Benefit-Risk Evaluation'' (E2C(R2) guidance) and ``E2C(R2) Periodic Benefit-Risk Evaluation Report--Questions and Answers'' (E2C(R2) Q&A guidance). These guidances were prepared under the auspices of the International Council for Harmonisation (ICH), formerly the International Conference on Harmonisation. The E2C(R2) draft guidance, issued April 11, 2012, updated and combined two ICH guidances, ``E2C Clinical Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (E2C guidance) and ``Addendum to E2C Clinical Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (addendum to the E2C guidance). The E2C(R2) guidance is intended to describe the format, content, and timing of a Periodic Benefit-Risk Evaluation Report (PBRER) for an approved drug or biologic, and it finalizes the draft guidance. The E2C(R2) Q&A guidance is a supplementary guidance that is intended to clarify key issues in the E2C(R2) guidance.

The 2006 Kennedy Space Center Range Reference Atmosphere Model Validation Study and Sensitivity Analysis to the Performance of the National Aeronautics and Space Administration's Space Shuttle Vehicle

NASA Technical Reports Server (NTRS)

Burns, Lee; Decker, Ryan; Harrington, Brian; Merry, Carl

2008-01-01

The Kennedy Space Center (KSC) Range Reference Atmosphere (RRA) is a statistical model that summarizes wind and thermodynamic atmospheric variability from surface to 70 km. The National Aeronautics and Space Administration's (NASA) Space Shuttle program, which launches from KSC, utilizes the KSC RRA data to evaluate environmental constraints on various aspects of the vehicle during ascent. An update to the KSC RRA was recently completed. As part of the update, the Natural Environments Branch at NASA's Marshall Space Flight Center (MSFC) conducted a validation study and a comparison analysis to the existing KSC RRA database version 1983. Assessments to the Space Shuttle vehicle ascent profile characteristics were performed by JSC/Ascent Flight Design Division to determine impacts of the updated model to the vehicle performance. Details on the model updates and the vehicle sensitivity analyses with the update model are presented.

Internal ballistics model update for ASRM dome

NASA Technical Reports Server (NTRS)

Bowden, Mark H.; Jenkins, Billy Z.

1991-01-01

A previous report (no. 5-32279, contract NAS8-36955, DO 51) describes the measures taken to adapt the NASA Complex Burning Region Model and code so that is was applicable to the Advanced Solid Rocket Motor as envisioned at that time. The code so modified was called the CBRM-A. CBRM-A could calculate the port volume and burning area for the star, transition, and cylindrically perforated regions of the motor. Described here is a subsequent effort to add computation of port volume and burning area for the Advanced Solid Rocket Motor head dome. Sample output, input, and overview of the models are included. The software was configured in two forms - a stand alone head dome code and a code integrating the head dome solution with the CBRM-A.

Update in women's health.

PubMed

Ganschow, Pamela S; Jacobs, Elizabeth A; Mackinnon, Jennifer; Charney, Pamela

2009-06-01

The aim of this clinical update is to summarize articles and guidelines published in the last year with the potential to change current clinical practice as it relates to women's health. We used two independent search strategies to identify articles relevant to women's health published between March 1, 2007 and February 29, 2008. First, we reviewed the Cochrane Database of Systematic Reviews and journal indices from the ACP Journal Club, Annals of Internal Medicine, Archives of Internal Medicine, British Medical Journal, Circulation, Diabetes, JAMA, JGIM, Journal of Women's Health, Lancet, NEJM, Obstetrics and Gynecology, and Women's Health Journal Watch. Second, we performed a MEDLINE search using the medical subject heading term "sex factors." The authors, who all have clinical and/or research experience in the area of women's health, reviewed all article titles, abstracts, and, when indicated, full publications. We excluded articles related to obstetrical aspects of women's health focusing on those relevant to general internists. We had two acceptance criteria, scientific rigor and potential to impact women's health. We also identified new and/or updated women's health guidelines released during the same time period. We identified over 250 publications with potential relevance to women's health. Forty-six articles were selected for presentation as part of the Clinical Update, and nine were selected for a more detailed discussion in this paper. Evidence-based women's health guidelines are listed in Table 1. Table 1 Important Women's Health Guidelines in 2007-2008: New or Updated Topic Issuing organization Updated recommendations and comments Mammography screening in women 40-4917 ACP Individualized risk assessment and informed decision making should be used to guide decisions about mammography screening in this age group. To aid in the risk assessment, a discussion of the risk factors, which if present in a woman in her 40s increases her risk to above that of an average 50-year-old woman, is provided in the guidelines. In addition, available risk prediction models, such as the NIH Web site calculator (http://www.cancer.gov/bcrisktool/) can also be used to estimate quantitative breast cancer risk. This model was updated in 2008 with race-specific data for calculating risk in African-American women.18 The harms and benefits of mammography should be discussed and incorporated along with a woman's preferences and breast cancer risk profile into the decision on when to begin screening. If a woman decides to forgo mammography, the decision should be readdressed every 1 to 2 years. STD screening guidelines19 USPSTF and CDC Routine screening for this infection is now recommended for ALL sexually active women age 24 and under, based on the recent high prevalence estimates for chlamydia It is not recommended for women (pregnant or nonpregnant) age 25 and older, unless they are at increased risk for infection. STD treatment guidelines20 CDC Flouroquinolones are NO longer recommended for treatment of N. gonorrhea, due to increasing resistance (as high as 15% of isolates in 2006). For uncomplicated infections, treatment of gonorrhea should be initiated with ceftriaxone 125 mg IM or cefixime 400 mg PO and co-treatment for chlamydia infection (unless ruled out with testing). Recent estimates demonstrate that almost 50% of persons with gonorrhea have concomitant chlamydia infection21. STD = sexually transmitted disease, NIH = National Institutes of Health, ACP = American College of Physicians, USPSTF = United States Prevention Services Task Force, CDC = Centers for Disease Control.

Accomplishments Under the Airport Improvement Program. Fiscal year 1987.

DTIC Science & Technology

1987-01-01

APRON PORTLAND INTERNATIONAL JETPORT (PRIMARY) 17 $312,300 INSTALL RUNWAY LIGHTING SYSTEM 1B $1,481,738 EXTENDAPRON PRESQUE ISLE 06 $99,000 RECONSTRUCT...LOCATION AND PROJECT FEDERAL NAME OF AIRPORT NUMBER FUNDS DESCRIPTION OF WORK o PENNSYLVANIA S4 $198,000 CONDUCT STATE SYSTEM PLAN UPDATE COMMONWEALTH...OF PENNSYLVANIA (CONTINUOUS) (SYSTEM PLAN) R5 $200,000 CONDUCT REGIONAL SYSTEM PLAN UPDATE DELAWARE VALLEY REGION (CONTINUOUS) (SYSTEM PLAN) RS

32 CFR 2004.11 - Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)].

Code of Federal Regulations, 2014 CFR

2014-07-01

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2012-07-01

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2013-07-01

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2011-07-01

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Post-Launch Status of Orbital ATK’s Mission to the International Space Station

NASA Image and Video Library

2017-11-12

On Nov. 12, Orbital ATK launched its Cygnus cargo spacecraft atop an Antares rocket to the International Space Station, from the Mid-Atlantic Regional Spaceport at NASA’s Wallops Flight Facility in Virginia. Following the launch mission managers provided a status update on the mission.

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Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

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Code of Federal Regulations, 2010 CFR

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Key algorithms used in GR02: A computer simulation model for predicting tree and stand growth

Treesearch

Garrett A. Hughes; Paul E. Sendak; Paul E. Sendak

1985-01-01

GR02 is an individual tree, distance-independent simulation model for predicting tree and stand growth over time. It performs five major functions during each run: (1) updates diameter at breast height, (2) updates total height, (3) estimates mortality, (4) determines regeneration, and (5) updates crown class.

User's guide to the MESOI diffusion model and to the utility programs UPDATE and LOGRVU

DOE Office of Scientific and Technical Information (OSTI.GOV)

Athey, G.F.; Allwine, K.J.; Ramsdell, J.V.

MESOI is an interactive, Lagrangian puff trajectory diffusion model. The model is documented separately (Ramsdell and Athey, 1981); this report is intended to provide MESOI users with the information needed to successfully conduct model simulations. The user is also provided with guidance in the use of the data file maintenance and review programs; UPDATE and LOGRVU. Complete examples are given for the operaton of all three programs and an appendix documents UPDATE and LOGRVU.

The Construction of Visual-spatial Situation Models in Children's Reading and Their Relation to Reading Comprehension

PubMed Central

Barnes, Marcia A.; Raghubar, Kimberly P.; Faulkner, Heather; Denton, Carolyn A.

2014-01-01

Readers construct mental models of situations described by text to comprehend what they read, updating these situation models based on explicitly described and inferred information about causal, temporal, and spatial relations. Fluent adult readers update their situation models while reading narrative text based in part on spatial location information that is consistent with the perspective of the protagonist. The current study investigates whether children update spatial situation models in a similar way, whether there are age-related changes in children's formation of spatial situation models during reading, and whether measures of the ability to construct and update spatial situation models are predictive of reading comprehension. Typically-developing children from ages 9 through 16 years (n=81) were familiarized with a physical model of a marketplace. Then the model was covered, and children read stories that described the movement of a protagonist through the marketplace and were administered items requiring memory for both explicitly stated and inferred information about the character's movements. Accuracy of responses and response times were evaluated. Results indicated that: (a) location and object information during reading appeared to be activated and updated not simply from explicit text-based information but from a mental model of the real world situation described by the text; (b) this pattern showed no age-related differences; and (c) the ability to update the situation model of the text based on inferred information, but not explicitly stated information, was uniquely predictive of reading comprehension after accounting for word decoding. PMID:24315376

A groundwater data assimilation application study in the Heihe mid-reach

NASA Astrophysics Data System (ADS)

Ragettli, S.; Marti, B. S.; Wolfgang, K.; Li, N.

2017-12-01

The present work focuses on modelling of the groundwater flow in the mid-reach of the endorheic river Heihe in the Zhangye oasis (Gansu province) in arid north-west China. In order to optimise the water resources management in the oasis, reliable forecasts of groundwater level development under different management options and environmental boundary conditions have to be produced. For this means, groundwater flow is modelled with Modflow and coupled to an Ensemble Kalman Filter programmed in Matlab. The model is updated with monthly time steps, featuring perturbed boundary conditions to account for uncertainty in model forcing. Constant biases between model and observations have been corrected prior to updating and compared to model runs without bias correction. Different options for data assimilation (states and/or parameters), updating frequency, and measures against filter inbreeding (damping factor, covariance inflation, spatial localization) have been tested against each other. Results show a high dependency of the Ensemble Kalman filter performance on the selection of observations for data assimilation. For the present regional model, bias correction is necessary for a good filter performance. A combination of spatial localization and covariance inflation is further advisable to reduce filter inbreeding problems. Best performance is achieved if parameter updates are not large, an indication for good prior model calibration. Asynchronous updating of parameter values once every five years (with data of the past five years) and synchronous updating of the groundwater levels is better suited for this groundwater system with not or slow changing parameter values than synchronous updating of both groundwater levels and parameters at every time step applying a damping factor. The filter is not able to correct time lags of signals.

Update: Advancement of Contact Dynamics Modeling for Human Spaceflight Simulation Applications

NASA Technical Reports Server (NTRS)

Brain, Thomas A.; Kovel, Erik B.; MacLean, John R.; Quiocho, Leslie J.

2017-01-01

Pong is a new software tool developed at the NASA Johnson Space Center that advances interference-based geometric contact dynamics based on 3D graphics models. The Pong software consists of three parts: a set of scripts to extract geometric data from 3D graphics models, a contact dynamics engine that provides collision detection and force calculations based on the extracted geometric data, and a set of scripts for visualizing the dynamics response with the 3D graphics models. The contact dynamics engine can be linked with an external multibody dynamics engine to provide an integrated multibody contact dynamics simulation. This paper provides a detailed overview of Pong including the overall approach and modeling capabilities, which encompasses force generation from contact primitives and friction to computational performance. Two specific Pong-based examples of International Space Station applications are discussed, and the related verification and validation using this new tool are also addressed.

A model of geomagnetic secular variation for 1980-1983

USGS Publications Warehouse

Peddie, N.W.; Zunde, A.K.

1987-01-01

We developed an updated model of the secular variation of the main geomagnetic field during 1980 through 1983 based on annual mean values for that interval from 148 worldwide magnetic observatories. The model consists of a series of 80 spherical harmonics, up to and including those of degree and order 8. We used it to form a proposal for the 1985 revision of the International Geomagnetic Reference Field (IGRF). Comparison of the new model, whose mean epoch is approximately 1982.0, with the Provisional Geomagnetic Reference Field for 1975-1980 (PGRF 1975), indicates that the moment of the centered-dipole part of the geomagnetic field is now decreasing faster than it was 5 years ago. The rate (in field units) indicated by PGRF 1975 was about -25 nT a-1, while for the new model it is -28 nT a-1. ?? 1987.

Risk prediction models for graft failure in kidney transplantation: a systematic review.

PubMed

Kaboré, Rémi; Haller, Maria C; Harambat, Jérôme; Heinze, Georg; Leffondré, Karen

2017-04-01

Risk prediction models are useful for identifying kidney recipients at high risk of graft failure, thus optimizing clinical care. Our objective was to systematically review the models that have been recently developed and validated to predict graft failure in kidney transplantation recipients. We used PubMed and Scopus to search for English, German and French language articles published in 2005-15. We selected studies that developed and validated a new risk prediction model for graft failure after kidney transplantation, or validated an existing model with or without updating the model. Data on recipient characteristics and predictors, as well as modelling and validation methods were extracted. In total, 39 articles met the inclusion criteria. Of these, 34 developed and validated a new risk prediction model and 5 validated an existing one with or without updating the model. The most frequently predicted outcome was graft failure, defined as dialysis, re-transplantation or death with functioning graft. Most studies used the Cox model. There was substantial variability in predictors used. In total, 25 studies used predictors measured at transplantation only, and 14 studies used predictors also measured after transplantation. Discrimination performance was reported in 87% of studies, while calibration was reported in 56%. Performance indicators were estimated using both internal and external validation in 13 studies, and using external validation only in 6 studies. Several prediction models for kidney graft failure in adults have been published. Our study highlights the need to better account for competing risks when applicable in such studies, and to adequately account for post-transplant measures of predictors in studies aiming at improving monitoring of kidney transplant recipients. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Design of Firmware Update Strategy in Tower Mounted Amplifier

NASA Astrophysics Data System (ADS)

Lv, Yi; Han, Shuqin

With rapid development of radio communication, Tower mounted amplifier (TMA) that conform to AISG protocol will be increasingly applied. Remote firmware update function is essential for TMA. In this paper, a method about remote firmware update that conforms to AISG2.0 is proposed. In this paper, defect of traditional firmware storage is given, and the implementation procedure of firmware storing that based on internal flash of STR755 was introduced. According to corresponding specification in aisg2.0, the process of firmware download and activation are provided in detail. The key point of bootloader was given. Application result shows that the strategy is reliable and highly secure.

Updating sea spray aerosol emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2

EPA Pesticide Factsheets

The uploaded data consists of the BRACE Na aerosol observations paired with CMAQ model output, the updated model's parameterization of sea salt aerosol emission size distribution, and the model's parameterization of the sea salt emission factor as a function of sea surface temperature. This dataset is associated with the following publication:Gantt , B., J. Kelly , and J. Bash. Updating sea spray aerosol emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2. Geoscientific Model Development. Copernicus Publications, Katlenburg-Lindau, GERMANY, 8: 3733-3746, (2015).

A generic biokinetic model for carbon-14 labelled compounds

NASA Astrophysics Data System (ADS)

Manger, Ryan Paul

Carbon-14, a radioactive nuclide, is used in many industrial applications. Due to its wide range of uses in industry, many workers are at risk of accidental internal exposure to 14C. Being a low energy beta emitter, 14C is not a significant external radiation hazard, but the internal consequences posed by 14C are important, especially because of its long half life of 5730 years [46]. The current biokinetic model recommended by the International Commission on Radiological Protection (ICRP) is a conservative estimate of how radiocarbon is treated by the human body. The ICRP generic radiocarbon model consists of a single compartment representing the entire human body. This compartment has a biological half life of 40 days yielding an effective dose coefficient of 5.8x10-10 Sv B q-1 [44, 45, 49, 53, 54]. This overestimates the dose of all radiocarbon compounds that have been studied [96]. An improved model has been developed that includes and alimentary tract, a urinary bladder, CO2 model, and an "Other" compartment used to model systemic tissues. The model can be adapted to replicate any excretion curve and excretion pattern. In addition, the effective dose coefficient produced by the updated model is near the mean effective dose coefficient of carbon compounds that have been considered in this research. The major areas of improvement are: more anatomically significant, a less conservative dose coefficient, and the ability to manipulate the model for known excretion data. Due to the wide variety of carbon compounds, it is suggested that specific biokinetic models be implemented for known radiocarbon substances. If the source of radiocarbon is dietary, then the physiologically based model proposed by Whillans [102] that splits all ingested radiocarbon compounds into carbohydrates, fats, and proteins should be used.

Finite Element Modeling of the NASA Langley Aluminum Testbed Cylinder

NASA Technical Reports Server (NTRS)

Grosveld, Ferdinand W.; Pritchard, Joselyn I.; Buehrle, Ralph D.; Pappa, Richard S.

2002-01-01

The NASA Langley Aluminum Testbed Cylinder (ATC) was designed to serve as a universal structure for evaluating structural acoustic codes, modeling techniques and optimization methods used in the prediction of aircraft interior noise. Finite element models were developed for the components of the ATC based on the geometric, structural and material properties of the physical test structure. Numerically predicted modal frequencies for the longitudinal stringer, ring frame and dome component models, and six assembled ATC configurations were compared with experimental modal survey data. The finite element models were updated and refined, using physical parameters, to increase correlation with the measured modal data. Excellent agreement, within an average 1.5% to 2.9%, was obtained between the predicted and measured modal frequencies of the stringer, frame and dome components. The predictions for the modal frequencies of the assembled component Configurations I through V were within an average 2.9% and 9.1%. Finite element modal analyses were performed for comparison with 3 psi and 6 psi internal pressurization conditions in Configuration VI. The modal frequencies were predicted by applying differential stiffness to the elements with pressure loading and creating reduced matrices for beam elements with offsets inside external superelements. The average disagreement between the measured and predicted differences for the 0 psi and 6 psi internal pressure conditions was less than 0.5%. Comparably good agreement was obtained for the differences between the 0 psi and 3 psi measured and predicted internal pressure conditions.

Overview of the CLIC detector and its physics potential

NASA Astrophysics Data System (ADS)

Ström, Rickard

2017-12-01

The CLIC detector and physics study (CLICdp) is an international collaboration that investigates the physics potential of the Compact Linear Collider (CLIC). CLIC is a high-energy electron-positron collider under development, aiming for centre-of-mass energies from a few hundred GeV to 3 TeV. In addition to physics studies based on full Monte Carlo simulations of signal and background processes, CLICdp performs cuttingedge hardware R&D. In this contribution CLICdp will present recent results from physics prospect studies, emphasising Higgs studies. Additionally the new CLIC detector model and the recently updated CLIC baseline staging scenario will be presented.

Aeromedical Disposition and Waiver Consideration for ISS Crewmembers

NASA Technical Reports Server (NTRS)

Taddeo, Terrance

2012-01-01

Aeromedical certification of astronauts and cosmonauts traveling to the International Space Station is a multi?-tiered process that involv es standards agreed to by the partner agencies, and participation by the individual agency aeromedical boards and a multilateral space medi cine board. Medical standards are updated continually by a multilater al working group. The boards operate by consensus and strive to achie ve effective decision making through experience, medical judgment, medical evidence and risk modeling. The aim of the certification process is to minimize the risk to the ISS program of loss of mission object ives due to human health issues.

Summary of 2016 Light Microscopy Module (LMM) Physical Science Experiments on ISS. Update of LMM Science Experiments and Facility Capabilities

NASA Technical Reports Server (NTRS)

Sicker, Ronald J.; Meyer, William V.; Foster, William M.; Fletcher, William A.; Williams, Stuart J.; Lee, Chang-Soo

2016-01-01

This presentation will feature a series of short, entertaining, and informative videos that describe the current status and science support for the Light Microscopy Module (LMM) facility on the International Space Station. These interviews will focus on current experiments and provide an overview of future capabilities. The recently completed experiments include nano-particle haloing, 3-D self-assembly with Janus particles and a model system for nano-particle drug delivery. The videos will share perspectives from the scientists, engineers, and managers working with the NASA Light Microscopy program.

Handbook of ecotoxicology, second edition

USGS Publications Warehouse

Hoffman, David J.; Rattner, Barnett A.; Burton, G. Allen; Cairns, John

2003-01-01

Handbook of Ecotoxicology, Second Edition focuses on toxic substances and how they affect ecosystems worldwide. It presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. This authoritative work is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

Simulated and observed 2010 floodwater elevations in selected river reaches in the Pawtuxet River Basin, Rhode Island

USGS Publications Warehouse

Zarriello, Phillip J.; Olson, Scott A.; Flynn, Robert H.; Strauch, Kellan R.; Murphy, Elizabeth A.

2014-01-01

Heavy, persistent rains from late February through March 2010 caused severe flooding that set, or nearly set, peaks of record for streamflows and water levels at many long-term streamgages in Rhode Island. In response to this event, hydraulic models were updated for selected reaches covering about 56 river miles in the Pawtuxet River Basin to simulate water-surface elevations (WSEs) at specified flows and boundary conditions. Reaches modeled included the main stem of the Pawtuxet River, the North and South Branches of the Pawtuxet River, Pocasset River, Simmons Brook, Dry Brook, Meshanticut Brook, Furnace Hill Brook, Flat River, Quidneck Brook, and two unnamed tributaries referred to as South Branch Pawtuxet River Tributary A1 and Tributary A2. All the hydraulic models were updated to Hydrologic Engineering Center-River Analysis System (HEC-RAS) version 4.1.0 using steady-state simulations. Updates to the models included incorporation of new field-survey data at structures, high resolution land-surface elevation data, and updated flood flows from a related study. The models were assessed using high-water marks (HWMs) obtained in a related study following the March– April 2010 flood and the simulated water levels at the 0.2-percent annual exceedance probability (AEP), which is the estimated AEP of the 2010 flood in the basin. HWMs were obtained at 110 sites along the main stem of the Pawtuxet River, the North and South Branches of the Pawtuxet River, Pocasset River, Simmons Brook, Furnace Hill Brook, Flat River, and Quidneck Brook. Differences between the 2010 HWM elevations and the simulated 0.2-percent AEP WSEs from flood insurance studies (FISs) and the updated models developed in this study varied with most differences attributed to the magnitude of the 0.2-percent AEP flows. WSEs from the updated models generally are in closer agreement with the observed 2010 HWMs than with the FIS WSEs. The improved agreement of the updated simulated water elevations to observed 2010 HWMs provides a measure of the hydraulic model performance, which indicates the updated models better represent flooding at other AEPs than the existing FIS models.

Linearized inversion of multiple scattering seismic energy

NASA Astrophysics Data System (ADS)

Aldawood, Ali; Hoteit, Ibrahim; Zuberi, Mohammad

2014-05-01

Internal multiples deteriorate the quality of the migrated image obtained conventionally by imaging single scattering energy. So, imaging seismic data with the single-scattering assumption does not locate multiple bounces events in their actual subsurface positions. However, imaging internal multiples properly has the potential to enhance the migrated image because they illuminate zones in the subsurface that are poorly illuminated by single scattering energy such as nearly vertical faults. Standard migration of these multiples provides subsurface reflectivity distributions with low spatial resolution and migration artifacts due to the limited recording aperture, coarse sources and receivers sampling, and the band-limited nature of the source wavelet. The resultant image obtained by the adjoint operator is a smoothed depiction of the true subsurface reflectivity model and is heavily masked by migration artifacts and the source wavelet fingerprint that needs to be properly deconvolved. Hence, we proposed a linearized least-square inversion scheme to mitigate the effect of the migration artifacts, enhance the spatial resolution, and provide more accurate amplitude information when imaging internal multiples. The proposed algorithm uses the least-square image based on single-scattering assumption as a constraint to invert for the part of the image that is illuminated by internal scattering energy. Then, we posed the problem of imaging double-scattering energy as a least-square minimization problem that requires solving the normal equation of the following form: GTGv = GTd, (1) where G is a linearized forward modeling operator that predicts double-scattered seismic data. Also, GT is a linearized adjoint operator that image double-scattered seismic data. Gradient-based optimization algorithms solve this linear system. Hence, we used a quasi-Newton optimization technique to find the least-square minimizer. In this approach, an estimate of the Hessian matrix that contains curvature information is modified at every iteration by a low-rank update based on gradient changes at every step. At each iteration, the data residual is imaged using GT to determine the model update. Application of the linearized inversion to synthetic data to image a vertical fault plane demonstrate the effectiveness of this methodology to properly delineate the vertical fault plane and give better amplitude information than the standard migrated image using the adjoint operator that takes into account internal multiples. Thus, least-square imaging of multiple scattering enhances the spatial resolution of the events illuminated by internal scattering energy. It also deconvolves the source signature and helps remove the fingerprint of the acquisition geometry. The final image is obtained by the superposition of the least-square solution based on single scattering assumption and the least-square solution based on double scattering assumption.

Imputatoin and Model-Based Updating Technique for Annual Forest Inventories

Treesearch

Ronald E. McRoberts

2001-01-01

The USDA Forest Service is developing an annual inventory system to establish the capability of producing annual estimates of timber volume and related variables. The inventory system features measurement of an annual sample of field plots with options for updating data for plots measured in previous years. One imputation and two model-based updating techniques are...

Quality Analysis of Open Street Map Data

NASA Astrophysics Data System (ADS)

Wang, M.; Li, Q.; Hu, Q.; Zhou, M.

2013-05-01

Crowd sourcing geographic data is an opensource geographic data which is contributed by lots of non-professionals and provided to the public. The typical crowd sourcing geographic data contains GPS track data like OpenStreetMap, collaborative map data like Wikimapia, social websites like Twitter and Facebook, POI signed by Jiepang user and so on. These data will provide canonical geographic information for pubic after treatment. As compared with conventional geographic data collection and update method, the crowd sourcing geographic data from the non-professional has characteristics or advantages of large data volume, high currency, abundance information and low cost and becomes a research hotspot of international geographic information science in the recent years. Large volume crowd sourcing geographic data with high currency provides a new solution for geospatial database updating while it need to solve the quality problem of crowd sourcing geographic data obtained from the non-professionals. In this paper, a quality analysis model for OpenStreetMap crowd sourcing geographic data is proposed. Firstly, a quality analysis framework is designed based on data characteristic analysis of OSM data. Secondly, a quality assessment model for OSM data by three different quality elements: completeness, thematic accuracy and positional accuracy is presented. Finally, take the OSM data of Wuhan for instance, the paper analyses and assesses the quality of OSM data with 2011 version of navigation map for reference. The result shows that the high-level roads and urban traffic network of OSM data has a high positional accuracy and completeness so that these OSM data can be used for updating of urban road network database.

Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria.

PubMed

Plotkin, Scott R; Blakeley, Jaishri O; Evans, D Gareth; Hanemann, C Oliver; Hulsebos, Theo J M; Hunter-Schaedle, Kim; Kalpana, Ganjam V; Korf, Bruce; Messiaen, Ludwine; Papi, Laura; Ratner, Nancy; Sherman, Larry S; Smith, Miriam J; Stemmer-Rachamimov, Anat O; Vitte, Jeremie; Giovannini, Marco

2013-03-01

Schwannomatosis is the third major form of neurofibromatosis and is characterized by the development of multiple schwannomas in the absence of bilateral vestibular schwannomas. The 2011 Schwannomatosis Update was organized by the Children's Tumor Foundation (www.ctf.org) and held in Los Angeles, CA, from June 5-8, 2011. This article summarizes the highlights presented at the Conference and represents the "state-of-the-field" in 2011. Genetic studies indicate that constitutional mutations in the SMARCB1 tumor suppressor gene occur in 40-50% of familial cases and in 8-10% of sporadic cases of schwannomatosis. Tumorigenesis is thought to occur through a four-hit, three-step model, beginning with a germline mutation in SMARCB1 (hit 1), followed by loss of a portion of chromosome 22 that contains the second SMARCB1 allele and one NF2 allele (hits 2 and 3), followed by mutation of the remaining wild-type NF2 allele (hit 4). Insights from research on HIV and pediatric rhabdoid tumors have shed light on potential molecular pathways that are dysregulated in schwannomatosis-related schwannomas. Mouse models of schwannomatosis have been developed and promise to further expand our understanding of tumorigenesis and the tumor microenvironment. Clinical reports have described the occurrence of intracranial meningiomas in schwannomatosis patients and in families with germline SMARCB1 mutations. The authors propose updated diagnostic criteria to incorporate new clinical and genetic findings since 2005. In the next 5 years, the authors expect that advances in basic research in the pathogenesis of schwannomatosis will lead toward clinical investigations of potential drug therapies. Copyright © 2013 Wiley Periodicals, Inc.

Piloting a Structured Practice Audit to Assess ACGME Milestones in Written Handoff Communication in Internal Medicine

PubMed Central

Martin, Shannon K.; Farnan, Jeanne M.; McConville, John F.; Arora, Vineet M.

2015-01-01

Background Written communication skills are integral to patient care handoffs. Residency programs require feasible assessment tools that provide timely formative and summative feedback, ideally linked to the Accreditation Council for Graduate Medical Education Milestones. Objective We describe the use of 1 such tool—UPDATED—to assess written handoff communication skills in internal medicine interns. Methods During 2012–2013, the authors piloted a structured practice audit at 1 academic institution to audit written sign-outs completed by 45 interns, using the UPDATED tool, which scores 7 aspects of sign-out communication linked to milestones. Intern sign-outs were audited by trained faculty members throughout the year. Results were incorporated into intern performance reviews and Clinical Competency Committees. Results A total of 136 sign-outs were audited (averaging 3.1 audits per intern). In the first trimester, 14 interns (31%) had satisfactory audit results. Five interns (11%) had critical deficiencies and received immediate feedback, and the remaining 26 (58%) were assigned future audits due to missing audits or unsatisfactory scores. In the second trimester, 21 interns (68%) had satisfactory results, 1 had critical deficiencies, and 9 (29%) required future audits. Nine of the 10 remaining interns in the final trimester had satisfactory audits. Faculty time was estimated at 10 to 15 minutes per sign-out audited. Conclusions The UPDATED audit is a milestone-based tool that can be used to assess written sign-out communication skills in internal medicine residency programs. Future work is planned to adapt the tool for use by senior supervisory residents to appraise sign-outs in real time. PMID:26221442

Do executive functions explain the covariance between internalizing and externalizing behaviors?

PubMed

Hatoum, Alexander S; Rhee, Soo Hyun; Corley, Robin P; Hewitt, John K; Friedman, Naomi P

2017-11-16

This study examined whether executive functions (EFs) might be common features of internalizing and externalizing behavior problems across development. We examined relations between three EF latent variables (a common EF factor and factors specific to updating working memory and shifting sets), constructed from nine laboratory tasks administered at age 17, to latent growth intercept (capturing stability) and slope (capturing change) factors of teacher- and parent-reported internalizing and externalizing behaviors in 885 individual twins aged 7 to 16 years. We then estimated the proportion of intercept-intercept and slope-slope correlations predicted by EF as well as the association between EFs and a common psychopathology factor (P factor) estimated from all 9 years of internalizing and externalizing measures. Common EF was negatively associated with the intercepts of teacher-rated internalizing and externalizing behavior in males, and explained 32% of their covariance; in the P factor model, common EF was associated with the P factor in males. Shifting-specific was positively associated with the externalizing slope across sex. EFs did not explain covariation between parent-rated behaviors. These results suggest that EFs are associated with stable problem behavior variation, explain small proportions of covariance, and are a risk factor that that may depend on gender.

Prioritizing Information during Working Memory: Beyond Sustained Internal Attention.

PubMed

Myers, Nicholas E; Stokes, Mark G; Nobre, Anna C

2017-06-01

Working memory (WM) has limited capacity. This leaves attention with the important role of allowing into storage only the most relevant information. It is increasingly evident that attention is equally crucial for prioritizing representations within WM as the importance of individual items changes. Retrospective prioritization has been proposed to result from a focus of internal attention highlighting one of several representations. Here, we suggest an updated model, in which prioritization acts in multiple steps: first orienting towards and selecting a memory, and then reconfiguring its representational state in the service of upcoming task demands. Reconfiguration sets up an optimized perception-action mapping, obviating the need for sustained attention. This view is consistent with recent literature, makes testable predictions, and links WM with task switching and action preparation. Copyright © 2017 Elsevier Ltd. All rights reserved.

GHRS Cycle 5 Echelle Wavelength Monitor

NASA Astrophysics Data System (ADS)

Soderblom, David

1995-07-01

This proposal defines the spectral lamp test for Echelle A. It is an internal test which makes measurements of the wavelength lamp SC2. It calibrates the carrousel function, Y deflections, resolving power, sensitivity, and scattered light. The wavelength calibration dispersion constants will be updated in the PODPS calibration data base. This proposal defines the spectral lamp test for Echelle B. It is an internal test which makes measurements of the wavelength lamp SC2. It calibrates the carrousel function, Y deflections, resolving power, sensitivity, and scattered light. The wavelength calibration dispersion constants will be updated in the PODPS calibration data base. It will be run every 4 months. The wavelengths may be out of range according to PEPSI or TRANS. Please ignore the errors.

Benefits of Model Updating: A Case Study Using the Micro-Precision Interferometer Testbed

NASA Technical Reports Server (NTRS)

Neat, Gregory W.; Kissil, Andrew; Joshi, Sanjay S.

1997-01-01

This paper presents a case study on the benefits of model updating using the Micro-Precision Interferometer (MPI) testbed, a full-scale model of a future spaceborne optical interferometer located at JPL.

Preliminary Model of Porphyry Copper Deposits

USGS Publications Warehouse

Berger, Byron R.; Ayuso, Robert A.; Wynn, Jeffrey C.; Seal, Robert R.

2008-01-01

The U.S. Geological Survey (USGS) Mineral Resources Program develops mineral-deposit models for application in USGS mineral-resource assessments and other mineral resource-related activities within the USGS as well as for nongovernmental applications. Periodic updates of models are published in order to incorporate new concepts and findings on the occurrence, nature, and origin of specific mineral deposit types. This update is a preliminary model of porphyry copper deposits that begins an update process of porphyry copper models published in USGS Bulletin 1693 in 1986. This update includes a greater variety of deposit attributes than were included in the 1986 model as well as more information about each attribute. It also includes an expanded discussion of geophysical and remote sensing attributes and tools useful in resource evaluations, a summary of current theoretical concepts of porphyry copper deposit genesis, and a summary of the environmental attributes of unmined and mined deposits.

Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018.

PubMed

Maes, Piet; Alkhovsky, Sergey V; Bào, Yīmíng; Beer, Martin; Birkhead, Monica; Briese, Thomas; Buchmeier, Michael J; Calisher, Charles H; Charrel, Rémi N; Choi, Il Ryong; Clegg, Christopher S; de la Torre, Juan Carlos; Delwart, Eric; DeRisi, Joseph L; Di Bello, Patrick L; Di Serio, Francesco; Digiaro, Michele; Dolja, Valerian V; Drosten, Christian; Druciarek, Tobiasz Z; Du, Jiang; Ebihara, Hideki; Elbeaino, Toufic; Gergerich, Rose C; Gillis, Amethyst N; Gonzalez, Jean-Paul J; Haenni, Anne-Lise; Hepojoki, Jussi; Hetzel, Udo; Hồ, Thiện; Hóng, Ní; Jain, Rakesh K; Jansen van Vuren, Petrus; Jin, Qi; Jonson, Miranda Gilda; Junglen, Sandra; Keller, Karen E; Kemp, Alan; Kipar, Anja; Kondov, Nikola O; Koonin, Eugene V; Kormelink, Richard; Korzyukov, Yegor; Krupovic, Mart; Lambert, Amy J; Laney, Alma G; LeBreton, Matthew; Lukashevich, Igor S; Marklewitz, Marco; Markotter, Wanda; Martelli, Giovanni P; Martin, Robert R; Mielke-Ehret, Nicole; Mühlbach, Hans-Peter; Navarro, Beatriz; Ng, Terry Fei Fan; Nunes, Márcio Roberto Teixeira; Palacios, Gustavo; Pawęska, Janusz T; Peters, Clarence J; Plyusnin, Alexander; Radoshitzky, Sheli R; Romanowski, Víctor; Salmenperä, Pertteli; Salvato, Maria S; Sanfaçon, Hélène; Sasaya, Takahide; Schmaljohn, Connie; Schneider, Bradley S; Shirako, Yukio; Siddell, Stuart; Sironen, Tarja A; Stenglein, Mark D; Storm, Nadia; Sudini, Harikishan; Tesh, Robert B; Tzanetakis, Ioannis E; Uppala, Mangala; Vapalahti, Olli; Vasilakis, Nikos; Walker, Peter J; Wáng, Guópíng; Wáng, Lìpíng; Wáng, Yànxiăng; Wèi, Tàiyún; Wiley, Michael R; Wolf, Yuri I; Wolfe, Nathan D; Wú, Zhìqiáng; Xú, Wénxìng; Yang, Li; Yāng, Zuòkūn; Yeh, Shyi-Dong; Zhāng, Yǒng-Zhèn; Zhèng, Yàzhōu; Zhou, Xueping; Zhū, Chénxī; Zirkel, Florian; Kuhn, Jens H

2018-04-21

In 2018, the family Arenaviridae was expanded by inclusion of 1 new genus and 5 novel species. At the same time, the recently established order Bunyavirales was expanded by 3 species. This article presents the updated taxonomy of the family Arenaviridae and the order Bunyavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV) and summarizes additional taxonomic proposals that may affect the order in the near future.

Taxonomy of the order Mononegavirales: update 2016.

PubMed

Afonso, Claudio L; Amarasinghe, Gaya K; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R; Briand, François-Xavier; Briese, Thomas; Bukreyev, Alexander; Calisher, Charles H; Chandran, Kartik; Chéng, Jiāsēn; Clawson, Anna N; Collins, Peter L; Dietzgen, Ralf G; Dolnik, Olga; Domier, Leslie L; Dürrwald, Ralf; Dye, John M; Easton, Andrew J; Ebihara, Hideki; Farkas, Szilvia L; Freitas-Astúa, Juliana; Formenty, Pierre; Fouchier, Ron A M; Fù, Yànpíng; Ghedin, Elodie; Goodin, Michael M; Hewson, Roger; Horie, Masayuki; Hyndman, Timothy H; Jiāng, Dàohóng; Kitajima, Elliot W; Kobinger, Gary P; Kondo, Hideki; Kurath, Gael; Lamb, Robert A; Lenardon, Sergio; Leroy, Eric M; Li, Ci-Xiu; Lin, Xian-Dan; Liú, Lìjiāng; Longdon, Ben; Marton, Szilvia; Maisner, Andrea; Mühlberger, Elke; Netesov, Sergey V; Nowotny, Norbert; Patterson, Jean L; Payne, Susan L; Paweska, Janusz T; Randall, Rick E; Rima, Bertus K; Rota, Paul; Rubbenstroth, Dennis; Schwemmle, Martin; Shi, Mang; Smither, Sophie J; Stenglein, Mark D; Stone, David M; Takada, Ayato; Terregino, Calogero; Tesh, Robert B; Tian, Jun-Hua; Tomonaga, Keizo; Tordo, Noël; Towner, Jonathan S; Vasilakis, Nikos; Verbeek, Martin; Volchkov, Viktor E; Wahl-Jensen, Victoria; Walsh, John A; Walker, Peter J; Wang, David; Wang, Lin-Fa; Wetzel, Thierry; Whitfield, Anna E; Xiè, Ji Tāo; Yuen, Kwok-Yung; Zhang, Yong-Zhen; Kuhn, Jens H

2016-08-01

In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera (Anphevirus, Arlivirus, Chengtivirus, Crustavirus, and Wastrivirus), and several other changes at the genus and species levels. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV).

Taxonomy of the order Mononegavirales: update 2016

USGS Publications Warehouse

Afonso, C.L.; Kurath, Gael; 82 Additional Authors,

2016-01-01

In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera (Anphevirus, Arlivirus, Chengtivirus, Crustavirus, and Wastrivirus), and several other changes at the genus and species levels. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV).

Taxonomy of the order Mononegavirales: update 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián

2016-05-23

In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera (Anphevirus, Arlivirus, Chengtivirus, Crustavirus, and Wastrivirus), and several other changes at the genus and species levels. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV).

TAXONOMY OF THE ORDER MONONEGAVIRALES: UPDATE 2016

PubMed Central

Afonso, Claudio L.; Amarasinghe, Gaya K.; Bányai, Krisztián; Bào, Yīmíng; Basler, Christopher F.; Bavari, Sina; Bejerman, Nicolás; Blasdell, Kim R.; Briand, François-Xavier; Briese, Thomas; Bukreyev, Alexander; Calisher, Charles H.; Chandran, Kartik; Chéng, Jiāsēn; Clawson, Anna N.; Collins, Peter L.; Dietzgen, Ralf G.; Dolnik, Olga; Domier, Leslie L.; Dürrwald, Ralf; Dye, John M.; Easton, Andrew J.; Ebihara, Hideki; Farkas, Szilvia L.; Freitas-Astúa, Juliana; Formenty, Pierre; Fouchier, Ron A. M.; Fù, Yànpíng; Ghedin, Elodie; Goodin, Michael M.; Hewson, Roger; Horie, Masayuki; Hyndman, Timothy H.; Jiāng, Dàohóng; Kitajima, Elliot W.; Kobinger, Gary P.; Kondo, Hideki; Kurath, Gael; Lamb, Robert A.; Lenardon, Sergio; Leroy, Eric M.; Li, Ci-Xiu; Lin, Xian-Dan; Liú, Lìjiāng; Longdon, Ben; Marton, Szilvia; Maisner, Andrea; Mühlberger, Elke; Netesov, Sergey V.; Nowotny, Norbert; Patterson, Jean L.; Payne, Susan L.; Paweska, Janusz T.; Randall, Rick E.; Rima, Bertus K.; Rota, Paul; Rubbenstroth, Dennis; Schwemmle, Martin; Shi, Mang; Smither, Sophie J.; Stenglein, Mark D.; Stone, David M.; Takada, Ayato; Terregino, Calogero; Tesh, Robert B.; Tian, Jun-Hua; Tomonaga, Keizo; Tordo, Noël; Towner, Jonathan S.; Vasilakis, Nikos; Verbeek, Martin; Volchkov, Viktor E.; Wahl-Jensen, Victoria; Walsh, John A.; Walker, Peter J.; Wang, David; Wang, Lin-Fa; Wetzel, Thierry; Whitfield, Anna E.; Xiè, Jiǎtāo; Yuen, Kwok-Yung; Zhang, Yong-Zhen; Kuhn, Jens H.

2016-01-01

In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae and Sunviridae), the elevation of the paramyxoviral subfamily Pneumovirinae to family status (Pneumoviridae), the addition of five free-floating genera (Anphevirus, Arlivirus, Chengtivirus, Crustavirus, and Wastrivirus), and several other changes at the genus and species levels. This article presents the updated taxonomy of the order Mononegavirales as now accepted by the International Committee on Taxonomy of Viruses (ICTV). PMID:27216929

Global Deployment Anaylsis System Algorithm Description (With Updates)

DTIC Science & Technology

1998-09-01

Global Deployment Analysis System Algorithm Description (with Updates) By Noetics , Inc. For U.S. Army Concepts Analysis Agency Contract...t "O -Q £5.3 Q 20000224 107 aQU’no-bi-o^f r This Algorithm Description for the Global Deployment Analysis System (GDAS) was prepared by Noetics ...support for Paradox Runtime will be provided by the GDAS developers, CAA and Noetics Inc., and not by Borland International. GDAS for Windows has

Modeling good research practices--overview: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force--1.

PubMed

Caro, J Jaime; Briggs, Andrew H; Siebert, Uwe; Kuntz, Karen M

2012-01-01

Models--mathematical frameworks that facilitate estimation of the consequences of health care decisions--have become essential tools for health technology assessment. Evolution of the methods since the first ISPOR Modeling Task Force reported in 2003 has led to a new Task Force, jointly convened with the Society for Medical Decision Making, and this series of seven articles presents the updated recommendations for best practices in conceptualizing models; implementing state-transition approaches, discrete event simulations, or dynamic transmission models; and dealing with uncertainty and validating and reporting models transparently. This overview article introduces the work of the Task Force, provides all the recommendations, and discusses some quandaries that require further elucidation. The audience for these articles includes those who build models, stakeholders who utilize their results, and, indeed, anyone concerned with the use of models to support decision making. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Updating older forest inventory data with a growth model and satellite records to improve the responsiveness and currency of national carbon monitoring

NASA Astrophysics Data System (ADS)

Healey, S. P.; Zhao, F. R.; McCarter, J. B.; Frescino, T.; Goeking, S.

2017-12-01

International reporting of American forest carbon trends depends upon the Forest Service's nationally consistent network of inventory plots. Plots are measured on a rolling basis over a 5- to 10-year cycle, so estimates related to any variable, including carbon storage, reflect conditions over a 5- to 10-year window. This makes it difficult to identify the carbon impact of discrete events (e.g., a bad fire year; extraction rates related to home-building trends), particularly if the events are recent.We report an approach to make inventory estimates more sensitive to discrete and recent events. We use a growth model (the Forest Vegetation Simulator - FVS) that is maintained by the Forest Service to annually update the tree list for every plot, allowing all plots to contribute to a series of single-year estimates. Satellite imagery from the Landsat platform guides the FVS simulations by providing information about which plots have been disturbed, which are recovering from disturbance, and which are undergoing undisturbed growth. The FVS model is only used to "update" plot tree lists until the next field measurement is made (maximum of 9 years). As a result, predicted changes are usually small and error rates are low. We present a pilot study of this system in Idaho, which has experienced several major fire events in the last decade. Empirical estimates of uncertainty, accounting for both plot sampling error and FVS model error, suggest that this approach greatly increases temporal specificity and sensitivity to discrete events without sacrificing much estimate precision at the level of a US state. This approach has the potential to take better advantage of the Forest Service's rolling plot measurement schedule to report carbon storage in the US, and it offers the basis of a system that might allow near-term, forward-looking analysis of the effects of hypothetical forest disturbance patterns.

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. At left, Susan Fernandez from the Office of Senator Marco Rubio talks with another attendee near the Education display. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. An attendee talks with Trent Smith, program manager, and Tammy Belk, a program specialist, at the ISS Ground Processing and Research Office display. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Build-Up Approach to Updating the Mock Quiet Spike Beam Model

NASA Technical Reports Server (NTRS)

Herrera, Claudia Y.; Pak, Chan-gi

2007-01-01

When a new aircraft is designed or a modification is done to an existing aircraft, the aeroelastic properties of the aircraft should be examined to ensure the aircraft is flight worthy. Evaluating the aeroelastic properties of a new or modified aircraft can include performing a variety of analyses, such as modal and flutter analyses. In order to produce accurate results from these analyses, it is imperative to work with finite element models (FEM) that have been validated by or correlated to ground vibration test (GVT) data, Updating an analytical model using measured data is a challenge in the area of structural dynamics. The analytical model update process encompasses a series of optimizations that match analytical frequencies and mode shapes to the measured modal characteristics of structure. In the past, the method used to update a model to test data was "trial and error." This is an inefficient method - running a modal analysis, comparing the analytical results to the GVT data, manually modifying one or more structural parameters (mass, CG, inertia, area, etc.), rerunning the analysis, and comparing the new analytical modal characteristics to the GVT modal data. If the match is close enough (close enough defined by analyst's updating requirements), then the updating process is completed. If the match does not meet updating-requirements, then the parameters are changed again and the process is repeated. Clearly, this manual optimization process is highly inefficient for large FEM's and/or a large number of structural parameters. NASA Dryden Flight Research Center (DFRC) has developed, in-house, a Mode Matching Code that automates the above-mentioned optimization process, DFRC's in-house Mode Matching Code reads mode shapes and frequencies acquired from GVT to create the target model. It also reads the current analytical model, as we11 as the design variables and their upper and lower limits. It performs a modal analysis on this model and modifies it to create an updated model that has similar mode shapes and frequencies as those of the target model. The Mode Matching Code output frequencies and modal assurance criteria (MAC) values that allow for the quantified comparison of the updated model versus the target model. A recent application of this code is the F453 supersonic flight testing platform, NASA DFRC possesses a modified F-15B that is used as a test bed aircraft for supersonic flight experiments. Traditionally, the finite element model of the test article is generated. A GVT is done on the test article ta validate and update its FEM. This FEM is then mated to the F-15B model, which was correlated to GVT data in fall of 2004, A GVT is conducted with the test article mated to the aircraft, and this mated F-15B/ test article FEM is correlated to this final GVT.

BC International-Student K-12 Enrolment and Tuition Fees in Decline: Update, 2009-10. BCTF Research Report. Section V. 2011-EF-01

ERIC Educational Resources Information Center

Kuehn, Larry; Field, Anne

2011-01-01

The years of ever-increasing revenue from international students appear to have come to an end. Data show that the number of international students and the revenue they generated rose annually throughout the first years of the past decade; however, enrolment and associated fee revenue for school districts reached its highest level in 2007-2008,…

77 FR 14046 - Amended Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

... Research and Production Act of 1993--ASTM International Standards Notice is hereby given that, on February..., 15 U.S.C. 4301 et seq. (``the Act''), ASTM International Standards (``ASTM'') has filed written... circumstances. Specifically, ASTM has provided an updated list of current, ongoing ASTM standards activities...

75 FR 13313 - Advisory Committee for International Science and Engineering; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... NATIONAL SCIENCE FOUNDATION Advisory Committee for International Science and Engineering; Notice... Science and Engineering ( 25104). Date/Time: April 19, 2010--8:30 a.m. to 5 p.m. April 20, 2010--8:30 a.m... Engineering. Agenda April 19, 2010 AM: Introductions and Updates--Presentation and Discussion of 2010...

77 FR 834 - Noise Exposure Map Update for Albany International Airport, Albany, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-06

... International Airport, under the provisions of 49 U.S.C. 47501 et. seq (Aviation Safety and Noise Abatement Act... December 19, 2011. Under 49 U.S.C. section 47503 of the Aviation Safety and Noise Abatement Act... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration [Docket No. 4910-13] Noise Exposure...

Nonlinear structural joint model updating based on instantaneous characteristics of dynamic responses

NASA Astrophysics Data System (ADS)

Wang, Zuo-Cai; Xin, Yu; Ren, Wei-Xin

2016-08-01

This paper proposes a new nonlinear joint model updating method for shear type structures based on the instantaneous characteristics of the decomposed structural dynamic responses. To obtain an accurate representation of a nonlinear system's dynamics, the nonlinear joint model is described as the nonlinear spring element with bilinear stiffness. The instantaneous frequencies and amplitudes of the decomposed mono-component are first extracted by the analytical mode decomposition (AMD) method. Then, an objective function based on the residuals of the instantaneous frequencies and amplitudes between the experimental structure and the nonlinear model is created for the nonlinear joint model updating. The optimal values of the nonlinear joint model parameters are obtained by minimizing the objective function using the simulated annealing global optimization method. To validate the effectiveness of the proposed method, a single-story shear type structure subjected to earthquake and harmonic excitations is simulated as a numerical example. Then, a beam structure with multiple local nonlinear elements subjected to earthquake excitation is also simulated. The nonlinear beam structure is updated based on the global and local model using the proposed method. The results show that the proposed local nonlinear model updating method is more effective for structures with multiple local nonlinear elements. Finally, the proposed method is verified by the shake table test of a real high voltage switch structure. The accuracy of the proposed method is quantified both in numerical and experimental applications using the defined error indices. Both the numerical and experimental results have shown that the proposed method can effectively update the nonlinear joint model.

Simulated and observed 2010 floodwater elevations in the Pawcatuck and Wood Rivers, Rhode Island

USGS Publications Warehouse

Zarriello, Phillip J.; Straub, David E.; Smith, Thor E.

2014-01-01

Heavy, persistent rains from late February through March 2010 caused severe flooding that set, or nearly set, peaks of record for streamflows and water levels at many long-term U.S. Geological Survey streamgages in Rhode Island. In response to this flood, hydraulic models of Pawcatuck River (26.9 miles) and Wood River (11.6 miles) were updated from the most recent approved U.S. Department of Homeland Security-Federal Emergency Management Agency flood insurance study (FIS) to simulate water-surface elevations (WSEs) for specified flows and boundary conditions. The hydraulic models were updated to Hydrologic Engineering Center-River Analysis System (HEC-RAS) using steady-state simulations and incorporate new field-survey data at structures, high resolution land-surface elevation data, and updated flood flows from a related study. The models were used to simulate the 0.2-percent annual exceedance probability (AEP) flood, which is the AEP determined for the 2010 flood in the Pawcatuck and Wood Rivers. The simulated WSEs were compared to high-water mark (HWM) elevation data obtained in a related study following the March–April 2010 flood, which included 39 HWMs along the Pawcatuck River and 11 HWMs along the Wood River. The 2010 peak flow generally was larger than the 0.2-percent AEP flow, which, in part, resulted in the FIS and updated model WSEs to be lower than the 2010 HWMs. The 2010 HWMs for the Pawcatuck River averaged about 1.6 feet (ft) higher than the 0.2-percent AEP WSEs simulated in the updated model and 2.5 ft higher than the WSEs in the FIS. The 2010 HWMs for the Wood River averaged about 1.3 ft higher than the WSEs simulated in the updated model and 2.5 ft higher than the WSEs in the FIS. The improved agreement of the updated simulated water elevations to observed 2010 HWMs provides a measure of the hydraulic model performance, which indicates the updated models better represent flooding at other AEPs than the existing FIS models.

Management of undescended testis may be improved with educational updates and new transferring model.

PubMed

Yi, Wei; Sheng-de, Wu; Lian-Ju, Shen; Tao, Lin; Da-Wei, He; Guang-Hui, Wei

2018-05-24

To investigate whether management of undescended testis (UDT) may be improved with educational updates and new transferring model among referring providers (RPs). The age of orchidopexies performed in Children's Hospital of Chongqing Medical University were reviewed. We then proposed educational updates and new transferring model among RPs. The age of orchidopexies performed after our intervention were collected. Data were represented graphically and statistical analysis Chi-square for trend were used. A total of 1543 orchidopexies were performed. The median age of orchidopexy did not matched the target age of 6-12 months in any subsequent year. Survey of the RPs showed that 48.85% of their recommended age was below 12 months. However, only 25.50% of them would directly make a surgical referral to pediatric surgery specifically at this point. After we proposed educational updates, tracking the age of orchidopexy revealed a statistically significant trend downward. The management of undescended testis may be improved with educational updates and new transferring model among primary healthcare practitioners.

The international WAO/EAACI guideline for the management of hereditary angioedema-The 2017 revision and update.

PubMed

Maurer, M; Magerl, M; Ansotegui, I; Aygören-Pürsün, E; Betschel, S; Bork, K; Bowen, T; Balle Boysen, H; Farkas, H; Grumach, A S; Hide, M; Katelaris, C; Lockey, R; Longhurst, H; Lumry, W R; Martinez-Saguer, I; Moldovan, D; Nast, A; Pawankar, R; Potter, P; Riedl, M; Ritchie, B; Rosenwasser, L; Sánchez-Borges, M; Zhi, Y; Zuraw, B; Craig, T

2018-01-10

Hereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and appropriate therapy are essential. This update and revision of the global guideline for HAE provides up-to-date consensus recommendations for the management of HAE. In the development of this update and revision of the guideline, an international expert panel reviewed the existing evidence and developed 20 recommendations that were discussed, finalized and consented during the guideline consensus conference in June 2016 in Vienna. The final version of this update and revision of the guideline incorporates the contributions of a board of expert reviewers and the endorsing societies. The goal of this guideline update and revision is to provide clinicians and their patients with guidance that will assist them in making rational decisions in the management of HAE with deficient C1-inhibitor (type 1) and HAE with dysfunctional C1-inhibitor (type 2). The key clinical questions covered by these recommendations are: (1) How should HAE-1/2 be defined and classified?, (2) How should HAE-1/2 be diagnosed?, (3) Should HAE-1/2 patients receive prophylactic and/or on-demand treatment and what treatment options should be used?, (4) Should HAE-1/2 management be different for special HAE-1/2 patient groups such as pregnant/lactating women or children?, and (5) Should HAE-1/2 management incorporate self-administration of therapies and patient support measures? © 2018 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Formulation of consumables management models: Consumables flight planning worksheet update. [space shuttles

NASA Technical Reports Server (NTRS)

Newman, C. M.

1977-01-01

The updated consumables flight planning worksheet (CFPWS) is documented. The update includes: (1) additional consumables: ECLSS ammonia, APU propellant, HYD water; (2) additional on orbit activity for development flight instrumentation (DFI); (3) updated use factors for all consumables; and (4) sources and derivations of the use factors.

Nonequivalence of updating rules in evolutionary games under high mutation rates.

PubMed

Kaiping, G A; Jacobs, G S; Cox, S J; Sluckin, T J

2014-10-01

Moran processes are often used to model selection in evolutionary simulations. The updating rule in Moran processes is a birth-death process, i. e., selection according to fitness of an individual to give birth, followed by the death of a random individual. For well-mixed populations with only two strategies this updating rule is known to be equivalent to selecting unfit individuals for death and then selecting randomly for procreation (biased death-birth process). It is, however, known that this equivalence does not hold when considering structured populations. Here we study whether changing the updating rule can also have an effect in well-mixed populations in the presence of more than two strategies and high mutation rates. We find, using three models from different areas of evolutionary simulation, that the choice of updating rule can change model results. We show, e. g., that going from the birth-death process to the death-birth process can change a public goods game with punishment from containing mostly defectors to having a majority of cooperative strategies. From the examples given we derive guidelines indicating when the choice of the updating rule can be expected to have an impact on the results of the model.

Nonequivalence of updating rules in evolutionary games under high mutation rates

NASA Astrophysics Data System (ADS)

Kaiping, G. A.; Jacobs, G. S.; Cox, S. J.; Sluckin, T. J.

2014-10-01

Moran processes are often used to model selection in evolutionary simulations. The updating rule in Moran processes is a birth-death process, i. e., selection according to fitness of an individual to give birth, followed by the death of a random individual. For well-mixed populations with only two strategies this updating rule is known to be equivalent to selecting unfit individuals for death and then selecting randomly for procreation (biased death-birth process). It is, however, known that this equivalence does not hold when considering structured populations. Here we study whether changing the updating rule can also have an effect in well-mixed populations in the presence of more than two strategies and high mutation rates. We find, using three models from different areas of evolutionary simulation, that the choice of updating rule can change model results. We show, e. g., that going from the birth-death process to the death-birth process can change a public goods game with punishment from containing mostly defectors to having a majority of cooperative strategies. From the examples given we derive guidelines indicating when the choice of the updating rule can be expected to have an impact on the results of the model.

Using a neural network approach and time series data from an international monitoring station in the Yellow Sea for modeling marine ecosystems.

PubMed

Zhang, Yingying; Wang, Juncheng; Vorontsov, A M; Hou, Guangli; Nikanorova, M N; Wang, Hongliang

2014-01-01

The international marine ecological safety monitoring demonstration station in the Yellow Sea was developed as a collaborative project between China and Russia. It is a nonprofit technical workstation designed as a facility for marine scientific research for public welfare. By undertaking long-term monitoring of the marine environment and automatic data collection, this station will provide valuable information for marine ecological protection and disaster prevention and reduction. The results of some initial research by scientists at the research station into predictive modeling of marine ecological environments and early warning are described in this paper. Marine ecological processes are influenced by many factors including hydrological and meteorological conditions, biological factors, and human activities. Consequently, it is very difficult to incorporate all these influences and their interactions in a deterministic or analysis model. A prediction model integrating a time series prediction approach with neural network nonlinear modeling is proposed for marine ecological parameters. The model explores the natural fluctuations in marine ecological parameters by learning from the latest observed data automatically, and then predicting future values of the parameter. The model is updated in a "rolling" fashion with new observed data from the monitoring station. Prediction experiments results showed that the neural network prediction model based on time series data is effective for marine ecological prediction and can be used for the development of early warning systems.

An updated concept of coagulation with clinical implications.

PubMed

Romney, Gregory; Glick, Michael

2009-05-01

Over the past century, a series of models have been put forth to explain the coagulation mechanism. The coagulation cascade/waterfall model has gained the most widespread acceptance. This model, however, has problems when it is used in different clinical scenarios. A more recently proposed cell-based model better describes the coagulation process in vivo and provides oral health care professionals (OHCPs) with a better understanding of the clinical implications of providing dental care to patients with potentially increased bleeding tendencies. The authors conducted a literature search using the PubMed database. They searched for key words including "coagulation," "hemostasis," "bleeding," "coagulation factors," "models," "prothrombin time," "activated partial thromboplastin time," "international normalized ratio," "anticoagulation therapy" and "hemophilia" separately and in combination. The coagulation cascade/waterfall model is insufficient to explain coagulation in vivo, predict a patient's bleeding tendency, or correlate clinical outcomes with specific laboratory screening tests such as prothrombin time, activated partial thromboplastin time and international normalized ratio. However, the cell-based model of coagulation that reflects the in vivo process of coagulation provides insight into the clinical ramifications of treating dental patients with specific coagulation factor deficiencies. Understanding the in vivo coagulation process will help OHCPs better predict a patient's bleeding tendency. In addition, applying the theoretical concept of the cell-based model of coagulation to commonly used laboratory screening tests for coagulation and bleeding will result in safer and more appropriate dental care.

OSATE Overview & Community Updates

DTIC Science & Technology

2015-02-15

update 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Delange /Julien 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...main language capabilities Modeling patterns & model samples for beginners Error-Model examples EMV2 model constructs Demonstration of tools Case

The diagnostic value of specific IgE to Ara h 2 to predict peanut allergy in children is comparable to a validated and updated diagnostic prediction model.

PubMed

Klemans, Rob J B; Otte, Dianne; Knol, Mirjam; Knol, Edward F; Meijer, Yolanda; Gmelig-Meyling, Frits H J; Bruijnzeel-Koomen, Carla A F M; Knulst, André C; Pasmans, Suzanne G M A

2013-01-01

A diagnostic prediction model for peanut allergy in children was recently published, using 6 predictors: sex, age, history, skin prick test, peanut specific immunoglobulin E (sIgE), and total IgE minus peanut sIgE. To validate this model and update it by adding allergic rhinitis, atopic dermatitis, and sIgE to peanut components Ara h 1, 2, 3, and 8 as candidate predictors. To develop a new model based only on sIgE to peanut components. Validation was performed by testing discrimination (diagnostic value) with an area under the receiver operating characteristic curve and calibration (agreement between predicted and observed frequencies of peanut allergy) with the Hosmer-Lemeshow test and a calibration plot. The performance of the (updated) models was similarly analyzed. Validation of the model in 100 patients showed good discrimination (88%) but poor calibration (P < .001). In the updating process, age, history, and additional candidate predictors did not significantly increase discrimination, being 94%, and leaving only 4 predictors of the original model: sex, skin prick test, peanut sIgE, and total IgE minus sIgE. When building a model with sIgE to peanut components, Ara h 2 was the only predictor, with a discriminative ability of 90%. Cutoff values with 100% positive and negative predictive values could be calculated for both the updated model and sIgE to Ara h 2. In this way, the outcome of the food challenge could be predicted with 100% accuracy in 59% (updated model) and 50% (Ara h 2) of the patients. Discrimination of the validated model was good; however, calibration was poor. The discriminative ability of Ara h 2 was almost comparable to that of the updated model, containing 4 predictors. With both models, the need for peanut challenges could be reduced by at least 50%. Copyright © 2012 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

Description and evaluation of the Community Multiscale Air ...

EPA Pesticide Factsheets

The Community Multiscale Air Quality (CMAQ) model is a comprehensive multipollutant air quality modeling system developed and maintained by the US Environmental Protection Agency's (EPA) Office of Research and Development (ORD). Recently, version 5.1 of the CMAQ model (v5.1) was released to the public, incorporating a large number of science updates and extended capabilities over the previous release version of the model (v5.0.2). These updates include the following: improvements in the meteorological calculations in both CMAQ and the Weather Research and Forecast (WRF) model used to provide meteorological fields to CMAQ, updates to the gas and aerosol chemistry, revisions to the calculations of clouds and photolysis, and improvements to the dry and wet deposition in the model. Sensitivity simulations isolating several of the major updates to the modeling system show that changes to the meteorological calculations result in enhanced afternoon and early evening mixing in the model, periods when the model historically underestimates mixing. This enhanced mixing results in higher ozone (O3) mixing ratios on average due to reduced NO titration, and lower fine particulate matter (PM2. 5) concentrations due to greater dilution of primary pollutants (e.g., elemental and organic carbon). Updates to the clouds and photolysis calculations greatly improve consistency between the WRF and CMAQ models and result in generally higher O3 mixing ratios, primarily due to reduced

Enhancement of ELDA Tracker Based on CNN Features and Adaptive Model Update.

PubMed

Gao, Changxin; Shi, Huizhang; Yu, Jin-Gang; Sang, Nong

2016-04-15

Appearance representation and the observation model are the most important components in designing a robust visual tracking algorithm for video-based sensors. Additionally, the exemplar-based linear discriminant analysis (ELDA) model has shown good performance in object tracking. Based on that, we improve the ELDA tracking algorithm by deep convolutional neural network (CNN) features and adaptive model update. Deep CNN features have been successfully used in various computer vision tasks. Extracting CNN features on all of the candidate windows is time consuming. To address this problem, a two-step CNN feature extraction method is proposed by separately computing convolutional layers and fully-connected layers. Due to the strong discriminative ability of CNN features and the exemplar-based model, we update both object and background models to improve their adaptivity and to deal with the tradeoff between discriminative ability and adaptivity. An object updating method is proposed to select the "good" models (detectors), which are quite discriminative and uncorrelated to other selected models. Meanwhile, we build the background model as a Gaussian mixture model (GMM) to adapt to complex scenes, which is initialized offline and updated online. The proposed tracker is evaluated on a benchmark dataset of 50 video sequences with various challenges. It achieves the best overall performance among the compared state-of-the-art trackers, which demonstrates the effectiveness and robustness of our tracking algorithm.

Enhancement of ELDA Tracker Based on CNN Features and Adaptive Model Update

PubMed Central

Gao, Changxin; Shi, Huizhang; Yu, Jin-Gang; Sang, Nong

2016-01-01

Appearance representation and the observation model are the most important components in designing a robust visual tracking algorithm for video-based sensors. Additionally, the exemplar-based linear discriminant analysis (ELDA) model has shown good performance in object tracking. Based on that, we improve the ELDA tracking algorithm by deep convolutional neural network (CNN) features and adaptive model update. Deep CNN features have been successfully used in various computer vision tasks. Extracting CNN features on all of the candidate windows is time consuming. To address this problem, a two-step CNN feature extraction method is proposed by separately computing convolutional layers and fully-connected layers. Due to the strong discriminative ability of CNN features and the exemplar-based model, we update both object and background models to improve their adaptivity and to deal with the tradeoff between discriminative ability and adaptivity. An object updating method is proposed to select the “good” models (detectors), which are quite discriminative and uncorrelated to other selected models. Meanwhile, we build the background model as a Gaussian mixture model (GMM) to adapt to complex scenes, which is initialized offline and updated online. The proposed tracker is evaluated on a benchmark dataset of 50 video sequences with various challenges. It achieves the best overall performance among the compared state-of-the-art trackers, which demonstrates the effectiveness and robustness of our tracking algorithm. PMID:27092505

An interval model updating strategy using interval response surface models

NASA Astrophysics Data System (ADS)

Fang, Sheng-En; Zhang, Qiu-Hu; Ren, Wei-Xin

2015-08-01

Stochastic model updating provides an effective way of handling uncertainties existing in real-world structures. In general, probabilistic theories, fuzzy mathematics or interval analyses are involved in the solution of inverse problems. However in practice, probability distributions or membership functions of structural parameters are often unavailable due to insufficient information of a structure. At this moment an interval model updating procedure shows its superiority in the aspect of problem simplification since only the upper and lower bounds of parameters and responses are sought. To this end, this study develops a new concept of interval response surface models for the purpose of efficiently implementing the interval model updating procedure. The frequent interval overestimation due to the use of interval arithmetic can be maximally avoided leading to accurate estimation of parameter intervals. Meanwhile, the establishment of an interval inverse problem is highly simplified, accompanied by a saving of computational costs. By this means a relatively simple and cost-efficient interval updating process can be achieved. Lastly, the feasibility and reliability of the developed method have been verified against a numerical mass-spring system and also against a set of experimentally tested steel plates.

Maintaining tumor targeting accuracy in real-time motion compensation systems for respiration-induced tumor motion.

PubMed

Malinowski, Kathleen; McAvoy, Thomas J; George, Rohini; Dieterich, Sonja; D'Souza, Warren D

2013-07-01

To determine how best to time respiratory surrogate-based tumor motion model updates by comparing a novel technique based on external measurements alone to three direct measurement methods. Concurrently measured tumor and respiratory surrogate positions from 166 treatment fractions for lung or pancreas lesions were analyzed. Partial-least-squares regression models of tumor position from marker motion were created from the first six measurements in each dataset. Successive tumor localizations were obtained at a rate of once per minute on average. Model updates were timed according to four methods: never, respiratory surrogate-based (when metrics based on respiratory surrogate measurements exceeded confidence limits), error-based (when localization error ≥ 3 mm), and always (approximately once per minute). Radial tumor displacement prediction errors (mean ± standard deviation) for the four schema described above were 2.4 ± 1.2, 1.9 ± 0.9, 1.9 ± 0.8, and 1.7 ± 0.8 mm, respectively. The never-update error was significantly larger than errors of the other methods. Mean update counts over 20 min were 0, 4, 9, and 24, respectively. The same improvement in tumor localization accuracy could be achieved through any of the three update methods, but significantly fewer updates were required when the respiratory surrogate method was utilized. This study establishes the feasibility of timing image acquisitions for updating respiratory surrogate models without direct tumor localization.

Cellular automaton model for molecular traffic jams

NASA Astrophysics Data System (ADS)

Belitsky, V.; Schütz, G. M.

2011-07-01

We consider the time evolution of an exactly solvable cellular automaton with random initial conditions both in the large-scale hydrodynamic limit and on the microscopic level. This model is a version of the totally asymmetric simple exclusion process with sublattice parallel update and thus may serve as a model for studying traffic jams in systems of self-driven particles. We study the emergence of shocks from the microscopic dynamics of the model. In particular, we introduce shock measures whose time evolution we can compute explicitly, both in the thermodynamic limit and for open boundaries where a boundary-induced phase transition driven by the motion of a shock occurs. The motion of the shock, which results from the collective dynamics of the exclusion particles, is a random walk with an internal degree of freedom that determines the jump direction. This type of hopping dynamics is reminiscent of some transport phenomena in biological systems.

Updating the Behavior Engineering Model.

ERIC Educational Resources Information Center

Chevalier, Roger

2003-01-01

Considers Thomas Gilbert's Behavior Engineering Model as a tool for systematically identifying barriers to individual and organizational performance. Includes a detailed case study and a performance aid that incorporates gap analysis, cause analysis, and force field analysis to update the original model. (Author/LRW)

What drives the perceptual change resulting from speech motor adaptation? Evaluation of hypotheses in a Bayesian modeling framework

PubMed Central

Perrier, Pascal; Schwartz, Jean-Luc; Diard, Julien

2018-01-01

Shifts in perceptual boundaries resulting from speech motor learning induced by perturbations of the auditory feedback were taken as evidence for the involvement of motor functions in auditory speech perception. Beyond this general statement, the precise mechanisms underlying this involvement are not yet fully understood. In this paper we propose a quantitative evaluation of some hypotheses concerning the motor and auditory updates that could result from motor learning, in the context of various assumptions about the roles of the auditory and somatosensory pathways in speech perception. This analysis was made possible thanks to the use of a Bayesian model that implements these hypotheses by expressing the relationships between speech production and speech perception in a joint probability distribution. The evaluation focuses on how the hypotheses can (1) predict the location of perceptual boundary shifts once the perturbation has been removed, (2) account for the magnitude of the compensation in presence of the perturbation, and (3) describe the correlation between these two behavioral characteristics. Experimental findings about changes in speech perception following adaptation to auditory feedback perturbations serve as reference. Simulations suggest that they are compatible with a framework in which motor adaptation updates both the auditory-motor internal model and the auditory characterization of the perturbed phoneme, and where perception involves both auditory and somatosensory pathways. PMID:29357357

Seismic source characterization for the 2014 update of the U.S. National Seismic Hazard Model

USGS Publications Warehouse

Moschetti, Morgan P.; Powers, Peter; Petersen, Mark D.; Boyd, Oliver; Chen, Rui; Field, Edward H.; Frankel, Arthur; Haller, Kathleen; Harmsen, Stephen; Mueller, Charles S.; Wheeler, Russell; Zeng, Yuehua

2015-01-01

We present the updated seismic source characterization (SSC) for the 2014 update of the National Seismic Hazard Model (NSHM) for the conterminous United States. Construction of the seismic source models employs the methodology that was developed for the 1996 NSHM but includes new and updated data, data types, source models, and source parameters that reflect the current state of knowledge of earthquake occurrence and state of practice for seismic hazard analyses. We review the SSC parameterization and describe the methods used to estimate earthquake rates, magnitudes, locations, and geometries for all seismic source models, with an emphasis on new source model components. We highlight the effects that two new model components—incorporation of slip rates from combined geodetic-geologic inversions and the incorporation of adaptively smoothed seismicity models—have on probabilistic ground motions, because these sources span multiple regions of the conterminous United States and provide important additional epistemic uncertainty for the 2014 NSHM.

Model Updating of Complex Structures Using the Combination of Component Mode Synthesis and Kriging Predictor

PubMed Central

Li, Yan; Wang, Dejun; Zhang, Shaoyi

2014-01-01

Updating the structural model of complex structures is time-consuming due to the large size of the finite element model (FEM). Using conventional methods for these cases is computationally expensive or even impossible. A two-level method, which combined the Kriging predictor and the component mode synthesis (CMS) technique, was proposed to ensure the successful implementing of FEM updating of large-scale structures. In the first level, the CMS was applied to build a reasonable condensed FEM of complex structures. In the second level, the Kriging predictor that was deemed as a surrogate FEM in structural dynamics was generated based on the condensed FEM. Some key issues of the application of the metamodel (surrogate FEM) to FEM updating were also discussed. Finally, the effectiveness of the proposed method was demonstrated by updating the FEM of a real arch bridge with the measured modal parameters. PMID:24634612

Updated Panel-Method Computer Program

NASA Technical Reports Server (NTRS)

Ashby, Dale L.

1995-01-01

Panel code PMARC_12 (Panel Method Ames Research Center, version 12) computes potential-flow fields around complex three-dimensional bodies such as complete aircraft models. Contains several advanced features, including internal mathematical modeling of flow, time-stepping wake model for simulating either steady or unsteady motions, capability for Trefftz computation of drag induced by plane, and capability for computation of off-body and on-body streamlines, and capability of computation of boundary-layer parameters by use of two-dimensional integral boundary-layer method along surface streamlines. Investigators interested in visual representations of phenomena, may want to consider obtaining program GVS (ARC-13361), General visualization System. GVS is Silicon Graphics IRIS program created to support scientific-visualization needs of PMARC_12. GVS available separately from COSMIC. PMARC_12 written in standard FORTRAN 77, with exception of NAMELIST extension used for input.

L5 TM radiometric recalibration procedure using the internal calibration trends from the NLAPS trending database

USGS Publications Warehouse

Chander, G.; Haque, Md. O.; Micijevic, E.; Barsi, J.A.

2008-01-01

From the Landsat program's inception in 1972 to the present, the earth science user community has benefited from a historical record of remotely sensed data. The multispectral data from the Landsat 5 (L5) Thematic Mapper (TM) sensor provide the backbone for this extensive archive. Historically, the radiometric calibration procedure for this imagery used the instrument's response to the Internal Calibrator (IC) on a scene-by-scene basis to determine the gain and offset for each detector. The IC system degraded with time causing radiometric calibration errors up to 20 percent. In May 2003 the National Landsat Archive Production System (NLAPS) was updated to use a gain model rather than the scene acquisition specific IC gains to calibrate TM data processed in the United States. Further modification of the gain model was performed in 2007. L5 TM data that were processed using IC prior to the calibration update do not benefit from the recent calibration revisions. A procedure has been developed to give users the ability to recalibrate their existing Level-1 products. The best recalibration results are obtained if the work order report that was originally included in the standard data product delivery is available. However, many users may not have the original work order report. In such cases, the IC gain look-up table that was generated using the radiometric gain trends recorded in the NLAPS database can be used for recalibration. This paper discusses the procedure to recalibrate L5 TM data when the work order report originally used in processing is not available. A companion paper discusses the generation of the NLAPS IC gain and bias look-up tables required to perform the recalibration.

Impact of Cancer and Its Treatments on Cognitive Function: Advances in Research From the Paris International Cognition and Cancer Task Force Symposium and Update Since 2012.

PubMed

Joly, Florence; Giffard, Bénédicte; Rigal, Olivier; De Ruiter, Michiel B; Small, Brent J; Dubois, Martine; LeFel, Johan; Schagen, Sanne B; Ahles, Tim A; Wefel, Jeffrey S; Vardy, Janette L; Pancré, Véronique; Lange, Marie; Castel, Hélène

2015-12-01

Although cognitive impairments have been identified in patients with non-central nervous system cancer, especially breast cancer, the respective roles of cancer and therapies, and the mechanisms involved in cognitive dysfunction remain unclear. To report a state-of-the-art update from the International Cognitive and Cancer Task Force conference held in 2012. A report of the meeting and recent new perspectives are presented. Recent clinical data support that non-central nervous system cancer per se may be involved in cognitive dysfunctions associated with inflammation parameters. The role of chemotherapy on cognitive decline was confirmed in colorectal and testicular cancers. Whereas the impact of hormone therapy remains debatable, some studies support a negative impact of targeted therapies on cognition. Regarding interventions, preliminary results of cognitive rehabilitation showed encouraging results. The methodology of future longitudinal studies has to be optimized by a priori end points, the use of validated test batteries, and the inclusion of control groups. Comorbidities and aging are important factors to be taken into account in future studies. Preclinical studies in animal models highlighted the role of cancer itself on cognition and support the possible benefits of prevention/care during chemotherapy. Progress in neuroimaging will help specify neural processes affected by treatments. Clinical data and animal models confirmed that chemotherapy induces direct cognitive deficit. The benefits of cognitive rehabilitation are still to be confirmed. Studies evaluating the mechanisms underlying cognitive impairments using advanced neuroimaging techniques integrating the evaluation of genetic factors are ongoing. Copyright © 2015 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

EoC Study Update to Examine the Cost, Schedule and Technical Changes to NASA Projects

NASA Technical Reports Server (NTRS)

Bitten, Bob; Emmons, Debra; Shinn, Stephen; Scolese, Chris

2018-01-01

The original National Aeronautics and Space Administration (NASA) Explanation of Change (EoC) study was conducted in 2010 to understand the underlying causes of cost and schedule growth. The first study consisted of 25 missions launched from 2000 to 2010 and looked at the events that led to growth. These events were categorized into different bins that were rolled up to quantify whether the growth was due to internal planning, or internal execution, or from external forces and found that the growth was evenly distributed among those three categories. The result of the study presented nine considerations focused at reducing growth due to project external events and internal planning events. Although no one 'magic bullet' consideration was discovered in the previous work, the nine considerations taken as a whole were postulated to help reduce cost and schedule change in future NASA missions. A recent update was conducted that included investigating 8 missions developed since the previous study to determine if the results were different. Cost, schedule, and mass increases were analyzed from the start of Phase B through Preliminary Design Review and Critical Design Review to Launch. As shown in this paper, the results are better with overall cost and schedule growth being reduced. The paper will show a comparison of the previous results to the updated results to show specific reductions and provide an explanation of which recommendations were followed.

Information dissemination model for social media with constant updates

NASA Astrophysics Data System (ADS)

Zhu, Hui; Wu, Heng; Cao, Jin; Fu, Gang; Li, Hui

2018-07-01

With the development of social media tools and the pervasiveness of smart terminals, social media has become a significant source of information for many individuals. However, false information can spread rapidly, which may result in negative social impacts and serious economic losses. Thus, reducing the unfavorable effects of false information has become an urgent challenge. In this paper, a new competitive model called DMCU is proposed to describe the dissemination of information with constant updates in social media. In the model, we focus on the competitive relationship between the original false information and updated information, and then propose the priority of related information. To more effectively evaluate the effectiveness of the proposed model, data sets containing actual social media activity are utilized in experiments. Simulation results demonstrate that the DMCU model can precisely describe the process of information dissemination with constant updates, and that it can be used to forecast information dissemination trends on social media.

Seismic hazard in the eastern United States

USGS Publications Warehouse

Mueller, Charles; Boyd, Oliver; Petersen, Mark D.; Moschetti, Morgan P.; Rezaeian, Sanaz; Shumway, Allison

2015-01-01

The U.S. Geological Survey seismic hazard maps for the central and eastern United States were updated in 2014. We analyze results and changes for the eastern part of the region. Ratio maps are presented, along with tables of ground motions and deaggregations for selected cities. The Charleston fault model was revised, and a new fault source for Charlevoix was added. Background seismicity sources utilized an updated catalog, revised completeness and recurrence models, and a new adaptive smoothing procedure. Maximum-magnitude models and ground motion models were also updated. Broad, regional hazard reductions of 5%–20% are mostly attributed to new ground motion models with stronger near-source attenuation. The revised Charleston fault geometry redistributes local hazard, and the new Charlevoix source increases hazard in northern New England. Strong increases in mid- to high-frequency hazard at some locations—for example, southern New Hampshire, central Virginia, and eastern Tennessee—are attributed to updated catalogs and/or smoothing.

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. – NASA Kennedy Space Center Director Robert Cabana welcomes community leaders, business executives, educators, community organizers, and state and local government leaders to the Kennedy Space Center Visitor Complex Debus Center for the Kennedy Space Center Director Update. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Updating of visual orientation in a gravity-based reference frame.

PubMed

Niehof, Nynke; Tramper, Julian J; Doeller, Christian F; Medendorp, W Pieter

2017-10-01

The brain can use multiple reference frames to code line orientation, including head-, object-, and gravity-centered references. If these frames change orientation, their representations must be updated to keep register with actual line orientation. We tested this internal updating during head rotation in roll, exploiting the rod-and-frame effect: The illusory tilt of a vertical line surrounded by a tilted visual frame. If line orientation is stored relative to gravity, these distortions should also affect the updating process. Alternatively, if coding is head- or frame-centered, updating errors should be related to the changes in their orientation. Ten subjects were instructed to memorize the orientation of a briefly flashed line, surrounded by a tilted visual frame, then rotate their head, and subsequently judge the orientation of a second line relative to the memorized first while the frame was upright. Results showed that updating errors were mostly related to the amount of subjective distortion of gravity at both the initial and final head orientation, rather than to the amount of intervening head rotation. In some subjects, a smaller part of the updating error was also related to the change of visual frame orientation. We conclude that the brain relies primarily on a gravity-based reference to remember line orientation during head roll.

FORCARB2: An updated version of the U.S. Forest Carbon Budget Model

Treesearch

Linda S. Heath; Michael C. Nichols; James E. Smith; John R. Mills

2010-01-01

FORCARB2, an updated version of the U.S. FORest CARBon Budget Model (FORCARB), produces estimates of carbon stocks and stock changes for forest ecosystems and forest products at 5-year intervals. FORCARB2 includes a new methodology for carbon in harvested wood products, updated initial inventory data, a revised algorithm for dead wood, and now includes public forest...

Sequential updating of a new dynamic pharmacokinetic model for caffeine in premature neonates.

PubMed

Micallef, Sandrine; Amzal, Billy; Bach, Véronique; Chardon, Karen; Tourneux, Pierre; Bois, Frédéric Y

2007-01-01

Caffeine treatment is widely used in nursing care to reduce the risk of apnoea in premature neonates. To check the therapeutic efficacy of the treatment against apnoea, caffeine concentration in blood is an important indicator. The present study was aimed at building a pharmacokinetic model as a basis for a medical decision support tool. In the proposed model, time dependence of physiological parameters is introduced to describe rapid growth of neonates. To take into account the large variability in the population, the pharmacokinetic model is embedded in a population structure. The whole model is inferred within a Bayesian framework. To update caffeine concentration predictions as data of an incoming patient are collected, we propose a fast method that can be used in a medical context. This involves the sequential updating of model parameters (at individual and population levels) via a stochastic particle algorithm. Our model provides better predictions than the ones obtained with models previously published. We show, through an example, that sequential updating improves predictions of caffeine concentration in blood (reduce bias and length of credibility intervals). The update of the pharmacokinetic model using body mass and caffeine concentration data is studied. It shows how informative caffeine concentration data are in contrast to body mass data. This study provides the methodological basis to predict caffeine concentration in blood, after a given treatment if data are collected on the treated neonate.

Highly efficient model updating for structural condition assessment of large-scale bridges.

DOT National Transportation Integrated Search

2015-02-01

For eciently updating models of large-scale structures, the response surface (RS) method based on radial basis : functions (RBFs) is proposed to model the input-output relationship of structures. The key issues for applying : the proposed method a...

UPDATE ON EPA'S URBAN WATERSHED MANAGEMENT BRANCH MODELING ACTIVITIES

EPA Science Inventory

This paper provides the Stormwater Management Model (SWMM) user community with a description of the Environmental Protection Agency (EPA's) Office of Research and Development (ORD) approach to urban watershed modeling research and provides an update on current ORD SWMM-related pr...

Nursing care update: Internal radiation therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowdermilk, D.L.

Internal radiation therapy has been used in treating gynecological cancers for over 100 years. A variety of radioactive sources are currently used alone and in combination with other cancer treatments. Nurses need to be able to provide safe, comprehensive care to patients receiving internal radiation therapy while using precautions to keep the risks of exposure to a minimum. This article discusses current trends and issues related to such treatment for gynecological cancers.20 references.

Children's Well-Being: An International Comparison. A Report of the Select Committee on Children, Youth, and Families. One Hundred First Congress, Second Session together with Additional Minority Views. Committee Print.

ERIC Educational Resources Information Center

Hobbs, Frank; Lippman, Laura

This report presents international statistics on the status of children and families, and thus updates a 1988 fact sheet containing international comparisons of public policies promoting the well-being of children and families. Included in the report are data on basic demographic trends, family composition and marital dissolution, the economic…

Update schemes of multi-velocity floor field cellular automaton for pedestrian dynamics

NASA Astrophysics Data System (ADS)

Luo, Lin; Fu, Zhijian; Cheng, Han; Yang, Lizhong

2018-02-01

Modeling pedestrian movement is an interesting problem both in statistical physics and in computational physics. Update schemes of cellular automaton (CA) models for pedestrian dynamics govern the schedule of pedestrian movement. Usually, different update schemes make the models behave in different ways, which should be carefully recalibrated. Thus, in this paper, we investigated the influence of four different update schemes, namely parallel/synchronous scheme, random scheme, order-sequential scheme and shuffled scheme, on pedestrian dynamics. The multi-velocity floor field cellular automaton (FFCA) considering the changes of pedestrians' moving properties along walking paths and heterogeneity of pedestrians' walking abilities was used. As for parallel scheme only, the collisions detection and resolution should be considered, resulting in a great difference from any other update schemes. For pedestrian evacuation, the evacuation time is enlarged, and the difference in pedestrians' walking abilities is better reflected, under parallel scheme. In face of a bottleneck, for example a exit, using a parallel scheme leads to a longer congestion period and a more dispersive density distribution. The exit flow and the space-time distribution of density and velocity have significant discrepancies under four different update schemes when we simulate pedestrian flow with high desired velocity. Update schemes may have no influence on pedestrians in simulation to create tendency to follow others, but sequential and shuffled update scheme may enhance the effect of pedestrians' familiarity with environments.

Selective updating of working memory content modulates meso-cortico-striatal activity.

PubMed

Murty, Vishnu P; Sambataro, Fabio; Radulescu, Eugenia; Altamura, Mario; Iudicello, Jennifer; Zoltick, Bradley; Weinberger, Daniel R; Goldberg, Terry E; Mattay, Venkata S

2011-08-01

Accumulating evidence from non-human primates and computational modeling suggests that dopaminergic signals arising from the midbrain (substantia nigra/ventral tegmental area) mediate striatal gating of the prefrontal cortex during the selective updating of working memory. Using event-related functional magnetic resonance imaging, we explored the neural mechanisms underlying the selective updating of information stored in working memory. Participants were scanned during a novel working memory task that parses the neurophysiology underlying working memory maintenance, overwriting, and selective updating. Analyses revealed a functionally coupled network consisting of a midbrain region encompassing the substantia nigra/ventral tegmental area, caudate, and dorsolateral prefrontal cortex that was selectively engaged during working memory updating compared to the overwriting and maintenance of working memory content. Further analysis revealed differential midbrain-dorsolateral prefrontal interactions during selective updating between low-performing and high-performing individuals. These findings highlight the role of this meso-cortico-striatal circuitry during the selective updating of working memory in humans, which complements previous research in behavioral neuroscience and computational modeling. Published by Elsevier Inc.

Summary Report of Summer 2009 NGSI Human Capital Development Efforts at Lawrence Livermore National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dougan, A; Dreicer, M; Essner, J

2009-11-16

In 2009, Lawrence Livermore National Laboratory (LLNL) engaged in several activities to support NA-24's Next Generation Safeguards Initiative (NGSI). This report outlines LLNL's efforts to support Human Capital Development (HCD), one of five key components of NGSI managed by Dunbar Lockwood in the Office of International Regimes and Agreements (NA-243). There were five main LLNL summer safeguards HCD efforts sponsored by NGSI: (1) A joint Monterey Institute of International Studies/Center for Nonproliferation Studies-LLNL International Safeguards Policy and Information Analysis Course; (2) A Summer Safeguards Policy Internship Program at LLNL; (3) A Training in Environmental Sample Analysis for IAEA Safeguards Internship;more » (4) Safeguards Technology Internships; and (5) A joint LLNL-INL Summer Safeguards Lecture Series. In this report, we provide an overview of these five initiatives, an analysis of lessons learned, an update on the NGSI FY09 post-doc, and an update on students who participated in previous NGSI-sponsored LLNL safeguards HCD efforts.« less

DPOD2014: a new DORIS extension of ITRF2014 for Precise Orbit Determination

NASA Astrophysics Data System (ADS)

Moreaux, G.; Willis, P.; Lemoine, F. G.; Zelensky, N. P.

2016-12-01

As one of the tracking systems used to determine orbits of the altimeter mission satellites (such as TOPEX/Poseidon, Envisat, Jason-1/2/3 & Cryosat-2), the position of the DORIS tracking stations provides a fundamental reference for the estimation of the precise orbits and so, by extension is fundamental for the quality of the altimeter data and derived products. Therefore, the time evolution of the position of both the existing and the newest DORIS stations must be precisely modeled and regularly updated. To satisfy operational requirements for precise orbit determination and routine delivery of geodetic products, the International DORIS Service maintains the so-called DPOD solutions, which can be seen as extensions of the latest available ITRF solution from the International Earth Rotation and Reference Systems Service (IERS). In mid-2016, the IDS agreed to change the processing strategy of the DPOD solution. The new solution from the IDS Combination Center (CC) consists of a DORIS cumulative position and velocity solution using the latest IDS combined weekly solutions. The first objective of this study is to describe the new DPOD elaboration scheme and to show the IDS CC internal validation steps. The second purpose is to present the external validation process made by an external team before the new DPOD is made available to all the users. The elaboration and validation procedures will be illustrated by the presentation of first version of the DPOD2014 (ITRF2014 DORIS extension) and focus will be given on the update of the position and velocity of two DORIS sites: Everest (after Gorkha earthquake M7.8 in April 2015) and Thule (Greenland).

Higher Education and International Student Mobility in the Global Knowledge Economy: Revised and Updated Second Edition

ERIC Educational Resources Information Center

Guruz, Kemal

2011-01-01

Students and scholars leaving their homes in search of education and knowledge is not a new phenomenon. An indispensable resource for understanding the international mobility of students, this book reveals how the global mobility of such students, scholars, programs, and institutions of higher education have evolved over time. Kemal Guruz explores…

Rejoinder and an Update: Recent Advances in Correlates of Internalized Heterosexism

ERIC Educational Resources Information Center

Szymanski, Dawn M.; Kashubeck-West, Susan

2008-01-01

Three themes found across the reactions to the Major Contribution are discussed: agreement on the destructive nature of internalized heterosexism; the importance of focusing on resilience and other strengths shown by lesbian, gay, and bisexual individuals that enable them to be healthy in the face of oppression; and the need for further research…

Update on GPS Modernization Efforts

DTIC Science & Technology

2015-06-02

Bilateral Agreements • Adjacent Band Interference • International Committee On Global Navigation Satellite Systems ( GNSS ) Department of...Receivers • Distribute PRNs for the World - 120 for US and 90 for GNSS International Cooperation • 57 Authorized Allied Users - 25+ Years of...Cooperation • GNSS -Europe - Galilee - China - COMPASS -Russia - GLONASS - Japan - QZSS - India- IRNSS 5 GPS Modernization Program SPACE AND MISSILE

Internationalizing the Curriculum: Improving Learning through International Education-- Preparing Students for Success in a Global Society

ERIC Educational Resources Information Center

Guerin, Stephen H.

2009-01-01

In the expanded and updated version of "The World is Flat: A Brief History of the Twenty-First Century" (Friedman, 2006), Thomas Friedman cogently describes the promise and peril of an economic and geopolitical future shaped by the forces of globalization wrought by technologically driven global connectivity, international commerce, and…

ARED (Advanced-Resistive Exercise Device) Update

NASA Technical Reports Server (NTRS)

Ploutz-Snyder, Lori

2009-01-01

This viewgraph presentation describes ARED which is a new hardware exercise device for use on the International Space Station. Astronaut physiological adaptations, muscle parameters, and cardiovascular parameters are also reviewed.

Bilirubin - urine

MedlinePlus

... Direct bilirubin - urine Images Male urinary system References Berk PD, Korenblat KM. Approach to the patient with ... Review Date 5/21/2017 Updated by: Laura J. Martin, MD, MPH, ABIM Board Certified in Internal ...

75 FR 39089 - Shipping Coordinating Committee; Notice of Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-07

... for updating shipborne navigation and communications equipment --International Telecommunication Union... Classification Societies (IACS) unified interpretations Members of the public may attend this meeting up to the...

75 FR 31760 - Advisory Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

...'s agenda will include updates on international affairs, wheat standards, the Yamamoto sheller study, wheat functionality, and an overview of Federal Grain Inspection Service 2010 operations. For a copy of...

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. From left, Scott Thurston, Kennedy deputy of the spacecraft office of the Commercial Crew Program, talks with Scott Colloredo, director of the Center Planning and Development Directorate. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - Community leaders, business executives, educators, and state and local government leaders were updated on NASA Kennedy Space Center programs and accomplishments during Center Director Bob Cabana’s Center Director Update at the Debus Center at the Kennedy Space Center Visitor Complex in Florida. Attendees talk with Trey Carlson, Kennedy Master Planner, at the Center Planning and Development Directorate, or CPDD, display. In the background is Mario Busacca, chief of CPDD’s Spaceport Planning Office. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

A new version of the ERICA tool to facilitate impact assessments of radioactivity on wild plants and animals.

PubMed

Brown, J E; Alfonso, B; Avila, R; Beresford, N A; Copplestone, D; Hosseini, A

2016-03-01

A new version of the ERICA Tool (version 1.2) was released in November 2014; this constitutes the first major update of the Tool since release in 2007. The key features of the update are presented in this article. Of particular note are new transfer databases extracted from an international compilation of concentration ratios (CRwo-media) and the modification of 'extrapolation' approaches used to select transfer data in cases where information is not available. Bayesian updating approaches have been used in some cases to draw on relevant information that would otherwise have been excluded in the process of deriving CRwo-media statistics. All of these efforts have in turn led to the requirement to update Environmental Media Concentration Limits (EMCLs) used in Tier 1 assessments. Some of the significant changes with regard to EMCLs are highlighted. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

VizieR Online Data Catalog: AAVSO International Variable Star Index VSX (Watson+, 2006-2014)

NASA Astrophysics Data System (ADS)

Watson, C.; Henden, A. A.; Price, A.

2017-05-01

This file contains Galactic stars known or suspected to be variable. It lists all stars that have an entry in the AAVSO International Variable Star Index (VSX; http://www.aavso.org/vsx). The database consisted initially of the General Catalogue of Variable Stars (GCVS) and the New Catalogue of Suspected Variables (NSV) and was then supplemented with a large number of variable star catalogues, as well as individual variable star discoveries or variables found in the literature. Effort has also been invested to update the entries with the latest information regarding position, type and period and to remove duplicates. The VSX database is being continually updated and maintained. For historical reasons some objects outside of the Galaxy have been included. (3 data files).

Evolution of robot-assisted orthotopic ileal neobladder formation: a step-by-step update to the University of Southern California (USC) technique.

PubMed

Chopra, Sameer; de Castro Abreu, Andre Luis; Berger, Andre K; Sehgal, Shuchi; Gill, Inderbir; Aron, Monish; Desai, Mihir M

2017-01-01

To describe our, step-by-step, technique for robotic intracorporeal neobladder formation. The main surgical steps to forming the intracorporeal orthotopic ileal neobladder are: isolation of 65 cm of small bowel; small bowel anastomosis; bowel detubularisation; suture of the posterior wall of the neobladder; neobladder-urethral anastomosis and cross folding of the pouch; and uretero-enteral anastomosis. Improvements have been made to these steps to enhance time efficiency without compromising neobladder configuration. Our technical improvements have resulted in an improvement in operative time from 450 to 360 min. We describe an updated step-by-step technique of robot-assisted intracorporeal orthotopic ileal neobladder formation. © 2016 The Authors BJU International © 2016 BJU International Published by John Wiley & Sons Ltd.

VizieR Online Data Catalog: AAVSO International Variable Star Index VSX (Watson+, 2006-2014)

NASA Astrophysics Data System (ADS)

Watson, C.; Henden, A. A.; Price, A.

2018-05-01

This file contains Galactic stars known or suspected to be variable. It lists all stars that have an entry in the AAVSO International Variable Star Index (VSX; http://www.aavso.org/vsx). The database consisted initially of the General Catalogue of Variable Stars (GCVS) and the New Catalogue of Suspected Variables (NSV) and was then supplemented with a large number of variable star catalogues, as well as individual variable star discoveries or variables found in the literature. Effort has also been invested to update the entries with the latest information regarding position, type and period and to remove duplicates. The VSX database is being continually updated and maintained. For historical reasons some objects outside of the Galaxy have been included. (3 data files).

The reference individual of radiation protection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eckerman, K.F.; Cristy, M.

1995-12-31

The 70-kg {open_quotes}standard man{close_quotes} representing a typical Western adult male has been used in physiological models since at least the 1920s. In 1949 at the Chalk River conference, health physicists from the U.S., UK, and Canada agreed on the concept of a standard man to facilitate comparison of internal dose estimates. The 70-kg standard man included specifications of the masses of 25 organs and tissues, total body content of 15 elements, total water intake and output, water content of the body, and some anatomical and physiological data for the respiratory and gastrointestinal tracts. In 1959, in its Publication 2{sup 2}more » on permissible doses for internal radiation the International Commission on Radiological Protection (ICRP) modified standard man. In 1963 the ICRP established a task group to revise and extend the standard man concept. The name was changed later to Reference Man and the task group`s work was published in 1975 as ICRP Publication 23{sup 3}. Publication 23 similar to Publication 2, updates and documents the sources of the data. Data on women, children, and fetuses were also collected, where available, but these data were limited primarily to anatomical data and only a few reference values were established for these groups. Information assembled during the course of the effort on the Reference Man report was used at Oak Ridge National Laboratory (ORNL) to construct a mathematical representation of the body (a phantom) that was suitable for use with Monte Carlo methods in the calculation of organ doses. That effort was undertaken to improve estimates of dose from photon-emitting radionuclides residing within organs, so-called internal emitters. The phantom, although updated throughout the years, remains today as the basis for organ dose estimates in nuclear medicine and radiation protection and underlies the radiation risk data derived from the epidemiologic studies of the atomic bomb survivors of Hiroshima and Nagasaki.« less

SysML model of exoplanet archive functionality and activities

NASA Astrophysics Data System (ADS)

Ramirez, Solange

2016-08-01

The NASA Exoplanet Archive is an online service that serves data and information on exoplanets and their host stars to help astronomical research related to search for and characterization of extra-solar planetary systems. In order to provide the most up to date data sets to the users, the exoplanet archive performs weekly updates that include additions into the database and updates to the services as needed. These weekly updates are complex due to interfaces within the archive. I will be presenting a SysML model that helps us perform these update activities in a weekly basis.

Structural Finite Element Model Updating Using Vibration Tests and Modal Analysis for NPL footbridge - SHM demonstrator

NASA Astrophysics Data System (ADS)

Barton, E.; Middleton, C.; Koo, K.; Crocker, L.; Brownjohn, J.

2011-07-01

This paper presents the results from collaboration between the National Physical Laboratory (NPL) and the University of Sheffield on an ongoing research project at NPL. A 50 year old reinforced concrete footbridge has been converted to a full scale structural health monitoring (SHM) demonstrator. The structure is monitored using a variety of techniques; however, interrelating results and converting data to knowledge are not possible without a reliable numerical model. During the first stage of the project, the work concentrated on static loading and an FE model of the undamaged bridge was created, and updated, under specified static loading and temperature conditions. This model was found to accurately represent the response under static loading and it was used to identify locations for sensor installation. The next stage involves the evaluation of repair/strengthening patches under both static and dynamic loading. Therefore, before deliberately introducing significant damage, the first set of dynamic tests was conducted and modal properties were estimated. The measured modal properties did not match the modal analysis from the statically updated FE model; it was clear that the existing model required updating. This paper introduces the results of the dynamic testing and model updating. It is shown that the structure exhibits large non-linear, amplitude dependant characteristics. This creates a difficult updating process, but we attempt to produce the best linear representation of the structure. A sensitivity analysis is performed to determine the most sensitive locations for planned damage/repair scenarios and is used to decide whether additional sensors will be necessary.

An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE)

PubMed Central

Althof, Stanley E; McMahon, Chris G; Waldinger, Marcel D; Serefoglu, Ege Can; Shindel, Alan W; Adaikan, P Ganesan; Becher, Edgardo; Dean, John; Giuliano, Francois; Hellstrom, Wayne JG; Giraldi, Annamaria; Glina, Sidney; Incrocci, Luca; Jannini, Emmanuele; McCabe, Marita; Parish, Sharon; Rowland, David; Segraves, R Taylor; Sharlip, Ira; Torres, Luiz Otavio

2014-01-01

Introduction In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts. Aim The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts. Method A comprehensive literature review was performed. Results This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients. Conclusion Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years. Althof SE, McMahon CG, Waldinger MD, Serefoglu EC, Shindel AW, Adaikan PG, Becher E, Dean J, Giuliano F, Hellstrom WJG, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, and Torres LO. An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE). Sex Med 2014;2:60–90. PMID:25356302

Summary of Expansions, Updates, and Results in GREET® 2016 Suite of Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2016-10-01

This report documents the technical content of the expansions and updates in Argonne National Laboratory’s GREET® 2016 release and provides references and links to key documents related to these expansions and updates.

Electronic Education System Model-2

ERIC Educational Resources Information Center

Güllü, Fatih; Kuusik, Rein; Laanpere, Mart

2015-01-01

In this study we presented new EES Model-2 extended from EES model for more productive implementation in e-learning process design and modelling in higher education. The most updates were related to uppermost instructional layer. We updated learning processes object of the layer for adaptation of educational process for young and old people,…

Update of the Accounting Surface Along the Lower Colorado River

USGS Publications Warehouse

Wiele, Stephen M.; Leake, Stanley A.; Owen-Joyce, Sandra J.; McGuire, Emmet H.

2008-01-01

The accounting-surface method was developed in the 1990s by the U.S. Geological Survey, in cooperation with the Bureau of Reclamation, to identify wells outside the flood plain of the lower Colorado River that yield water that will be replaced by water from the river. This method was needed to identify which wells require an entitlement for diversion of water from the Colorado River and need to be included in accounting for consumptive use of Colorado River water as outlined in the Consolidated Decree of the United States Supreme Court in Arizona v. California. The method is based on the concept of a river aquifer and an accounting surface within the river aquifer. The study area includes the valley adjacent to the lower Colorado River and parts of some adjacent valleys in Arizona, California, Nevada, and Utah and extends from the east end of Lake Mead south to the southerly international boundary with Mexico. Contours for the original accounting surface were hand drawn based on the shape of the aquifer, water-surface elevations in the Colorado River and drainage ditches, and hydrologic judgment. This report documents an update of the original accounting surface based on updated water-surface elevations in the Colorado River and drainage ditches and the use of simple, physically based ground-water flow models to calculate the accounting surface in four areas adjacent to the free-flowing river.

Priors Engaged in Long-Latency Responses to Mechanical Perturbations Suggest a Rapid Update in State Estimation

PubMed Central

Crevecoeur, Frédéric; Scott, Stephen H.

2013-01-01

In every motor task, our brain must handle external forces acting on the body. For example, riding a bike on cobblestones or skating on irregular surface requires us to appropriately respond to external perturbations. In these situations, motor predictions cannot help anticipate the motion of the body induced by external factors, and direct use of delayed sensory feedback will tend to generate instability. Here, we show that to solve this problem the motor system uses a rapid sensory prediction to correct the estimated state of the limb. We used a postural task with mechanical perturbations to address whether sensory predictions were engaged in upper-limb corrective movements. Subjects altered their initial motor response in ∼60 ms, depending on the expected perturbation profile, suggesting the use of an internal model, or prior, in this corrective process. Further, we found trial-to-trial changes in corrective responses indicating a rapid update of these perturbation priors. We used a computational model based on Kalman filtering to show that the response modulation was compatible with a rapid correction of the estimated state engaged in the feedback response. Such a process may allow us to handle external disturbances encountered in virtually every physical activity, which is likely an important feature of skilled motor behaviour. PMID:23966846

Assembly: a resource for assembled genomes at NCBI

PubMed Central

Kitts, Paul A.; Church, Deanna M.; Thibaud-Nissen, Françoise; Choi, Jinna; Hem, Vichet; Sapojnikov, Victor; Smith, Robert G.; Tatusova, Tatiana; Xiang, Charlie; Zherikov, Andrey; DiCuccio, Michael; Murphy, Terence D.; Pruitt, Kim D.; Kimchi, Avi

2016-01-01

The NCBI Assembly database (www.ncbi.nlm.nih.gov/assembly/) provides stable accessioning and data tracking for genome assembly data. The model underlying the database can accommodate a range of assembly structures, including sets of unordered contig or scaffold sequences, bacterial genomes consisting of a single complete chromosome, or complex structures such as a human genome with modeled allelic variation. The database provides an assembly accession and version to unambiguously identify the set of sequences that make up a particular version of an assembly, and tracks changes to updated genome assemblies. The Assembly database reports metadata such as assembly names, simple statistical reports of the assembly (number of contigs and scaffolds, contiguity metrics such as contig N50, total sequence length and total gap length) as well as the assembly update history. The Assembly database also tracks the relationship between an assembly submitted to the International Nucleotide Sequence Database Consortium (INSDC) and the assembly represented in the NCBI RefSeq project. Users can find assemblies of interest by querying the Assembly Resource directly or by browsing available assemblies for a particular organism. Links in the Assembly Resource allow users to easily download sequence and annotations for current versions of genome assemblies from the NCBI genomes FTP site. PMID:26578580

Capital update factor: a new era approaches.

PubMed

Grimaldi, P L

1993-02-01

The Health Care Financing Administration (HCFA) has constructed a preliminary model of a new capital update method which is consistent with the framework being developed to refine the update method for PPS operating costs. HCFA's eventual goal is to develop a single update framework for operating and capital costs. Initial results suggest that adopting the new capital update method would reduce capital payments substantially, which might intensify creditor's concerns about extending loans to hospitals.

Proposed reporting model update creates dialogue between FASB and not-for-profits.

PubMed

Mosrie, Norman C

2016-04-01

Seeing a need to refresh the current guidelines, the Financial Accounting Standards Board (FASB) proposed an update to the financial accounting and reporting model for not-for-profit entities. In a response to solicited feedback, the board is now revisiting its proposed update and has set forth a plan to finalize its new guidelines. The FASB continues to solicit and respond to feedback as the process progresses.

Carotid duplex

MedlinePlus

... ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 5. Review Date 6/1/2015 Updated by: Daniel Kantor, ... the Florida Society of Neurology (FSN), Gainesville, FL. Review provided by VeriMed Healthcare Network. Internal review and ...

ALP - blood test

MedlinePlus

... Renal cell carcinoma Alternative Names Alkaline phosphatase References Berk PD, Korenblat KM. Approach to the patient with ... Review Date 5/21/2017 Updated by: Laura J. Martin, MD, MPH, ABIM Board Certified in Internal ...

ALP isoenzyme test

MedlinePlus

... Alkaline phosphatase isoenzyme test Images Blood test References Berk PD, Korenblat KM. Approach to the patient with ... Review Date 5/21/2017 Updated by: Laura J. Martin, MD, MPH, ABIM Board Certified in Internal ...

Nuclear Data Networks

Science.gov Websites

calibrations. NSDD The international network of Nuclear Structure and Decay Data evaluators Group of and updating of nuclear structure data contained in Evaluated Nuclear Structure Data File (ENSDF

Vibration analysis of resistance spot welding joint for dissimilar plate structure (mild steel 1010 and stainless steel 304)

NASA Astrophysics Data System (ADS)

Sani, M. S. M.; Nazri, N. A.; Alawi, D. A. J.

2017-09-01

Resistance spot welding (RSW) is a proficient joining method commonly used for sheet metal joining and become one of the oldest spot welding processes use in industry especially in the automotive. RSW involves the application of heat and pressure without neglecting time taken when joining two or more metal sheets at a localized area which is claimed as the most efficient welding process in metal fabrication. The purpose of this project is to perform model updating of RSW plate structure between mild steel 1010 and stainless steel 304. In order to do the updating, normal mode finite element analysis (FEA) and experimental modal analysis (EMA) have been carried out. Result shows that the discrepancies of natural frequency between FEA and EMA are below than 10 %. Sensitivity model updating is evaluated in order to make sure which parameters are influences in this structural dynamic modification. Young’s modulus and density both materials are indicate significant parameters to do model updating. As a conclusion, after perform model updating, total average error of dissimilar RSW plate is improved significantly.

NODA for EPA's Updated Ozone Transport Modeling

EPA Pesticide Factsheets

Find EPA's NODA for the Updated Ozone Transport Modeling Data for the 2008 Ozone National Ambient Air Quality Standard (NAAQS) along with the ExitExtension of Public Comment Period on CSAPR for the 2008 NAAQS.

A novel model of motor learning capable of developing an optimal movement control law online from scratch.

PubMed

Shimansky, Yury P; Kang, Tao; He, Jiping

2004-02-01

A computational model of a learning system (LS) is described that acquires knowledge and skill necessary for optimal control of a multisegmental limb dynamics (controlled object or CO), starting from "knowing" only the dimensionality of the object's state space. It is based on an optimal control problem setup different from that of reinforcement learning. The LS solves the optimal control problem online while practicing the manipulation of CO. The system's functional architecture comprises several adaptive components, each of which incorporates a number of mapping functions approximated based on artificial neural nets. Besides the internal model of the CO's dynamics and adaptive controller that computes the control law, the LS includes a new type of internal model, the minimal cost (IM(mc)) of moving the controlled object between a pair of states. That internal model appears critical for the LS's capacity to develop an optimal movement trajectory. The IM(mc) interacts with the adaptive controller in a cooperative manner. The controller provides an initial approximation of an optimal control action, which is further optimized in real time based on the IM(mc). The IM(mc) in turn provides information for updating the controller. The LS's performance was tested on the task of center-out reaching to eight randomly selected targets with a 2DOF limb model. The LS reached an optimal level of performance in a few tens of trials. It also quickly adapted to movement perturbations produced by two different types of external force field. The results suggest that the proposed design of a self-optimized control system can serve as a basis for the modeling of motor learning that includes the formation and adaptive modification of the plan of a goal-directed movement.

Maintaining tumor targeting accuracy in real-time motion compensation systems for respiration-induced tumor motion

PubMed Central

Malinowski, Kathleen; McAvoy, Thomas J.; George, Rohini; Dieterich, Sonja; D’Souza, Warren D.

2013-01-01

Purpose: To determine how best to time respiratory surrogate-based tumor motion model updates by comparing a novel technique based on external measurements alone to three direct measurement methods. Methods: Concurrently measured tumor and respiratory surrogate positions from 166 treatment fractions for lung or pancreas lesions were analyzed. Partial-least-squares regression models of tumor position from marker motion were created from the first six measurements in each dataset. Successive tumor localizations were obtained at a rate of once per minute on average. Model updates were timed according to four methods: never, respiratory surrogate-based (when metrics based on respiratory surrogate measurements exceeded confidence limits), error-based (when localization error ≥3 mm), and always (approximately once per minute). Results: Radial tumor displacement prediction errors (mean ± standard deviation) for the four schema described above were 2.4 ± 1.2, 1.9 ± 0.9, 1.9 ± 0.8, and 1.7 ± 0.8 mm, respectively. The never-update error was significantly larger than errors of the other methods. Mean update counts over 20 min were 0, 4, 9, and 24, respectively. Conclusions: The same improvement in tumor localization accuracy could be achieved through any of the three update methods, but significantly fewer updates were required when the respiratory surrogate method was utilized. This study establishes the feasibility of timing image acquisitions for updating respiratory surrogate models without direct tumor localization. PMID:23822413

Update to the USDA-ARS fixed-wing spray nozzle models

USDA-ARS?s Scientific Manuscript database

The current USDA ARS Aerial Spray Nozzle Models were updated to reflect both new standardized measurement methods and systems, as well as, to increase operational spray pressure, aircraft airspeed and nozzle orientation angle limits. The new models were developed using both Central Composite Design...

Lazy Updating of hubs can enable more realistic models by speeding up stochastic simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ehlert, Kurt; Loewe, Laurence, E-mail: loewe@wisc.edu; Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, Wisconsin 53715

2014-11-28

To respect the nature of discrete parts in a system, stochastic simulation algorithms (SSAs) must update for each action (i) all part counts and (ii) each action's probability of occurring next and its timing. This makes it expensive to simulate biological networks with well-connected “hubs” such as ATP that affect many actions. Temperature and volume also affect many actions and may be changed significantly in small steps by the network itself during fever and cell growth, respectively. Such trends matter for evolutionary questions, as cell volume determines doubling times and fever may affect survival, both key traits for biological evolution.more » Yet simulations often ignore such trends and assume constant environments to avoid many costly probability updates. Such computational convenience precludes analyses of important aspects of evolution. Here we present “Lazy Updating,” an add-on for SSAs designed to reduce the cost of simulating hubs. When a hub changes, Lazy Updating postpones all probability updates for reactions depending on this hub, until a threshold is crossed. Speedup is substantial if most computing time is spent on such updates. We implemented Lazy Updating for the Sorting Direct Method and it is easily integrated into other SSAs such as Gillespie's Direct Method or the Next Reaction Method. Testing on several toy models and a cellular metabolism model showed >10× faster simulations for its use-cases—with a small loss of accuracy. Thus we see Lazy Updating as a valuable tool for some special but important simulation problems that are difficult to address efficiently otherwise.« less

Occupational asthma in maritime environments: an update.

PubMed

Lucas, David; Lodde, Brice; Jepsen, Jørgen Riis; Dewitte, Jean-Dominique; Jegaden, Dominique

2016-01-01

In 2006 we published our first review based on the available literature on occupational asthma in maritime environments in the "International Maritime Health" journal. Since then, we have obtained a great deal of new knowledge on asthma in seafood workers and fishermen and on the impact of exposures from sulphites preservatives, container fumigants etc. in maritime workers. This review aims to provide an update of the current knowledge base about occupational asthma in a maritime context and to provide recommendations regarding medical surveillance of workers at risk.

Occupational Therapy and Primary Care: Updates and Trends

PubMed Central

Mroz, Tracy M.; Fogelberg, Donald J.; Leland, Natalie E.

2018-01-01

As our health care system continues to change, so do the opportunities for occupational therapy. This article provides an update to a 2012 Health Policy Perspectives on this topic. We identify new initiatives and opportunities in primary care, explore common challenges to integrating occupational therapy in primary care environments, and highlight international works that can support our efforts. We conclude by discussing next steps for occupational therapy practitioners in order to continue to progress our efforts in primary care. PMID:29689169

New Method for Updating Mean Time Between Failure for ISS Orbital Replaceable Units Consultation Report

NASA Technical Reports Server (NTRS)

Parsons, Vickie S.

2009-01-01

A request to conduct a peer review of the International Space Station (ISS) proposal to use Bayesian methodology for updating Mean Time Between Failure (MTBF) for ISS Orbital Replaceable Units (ORU) was submitted to the NASA Engineering and Safety Center (NESC) on September 20, 2005. The results were requested by October 20, 2005 in order to be available during the process of reworking the current ISS flight manifest. The results are included in this report.

Determination of replicate composite bone material properties using modal analysis.

PubMed

Leuridan, Steven; Goossens, Quentin; Pastrav, Leonard; Roosen, Jorg; Mulier, Michiel; Denis, Kathleen; Desmet, Wim; Sloten, Jos Vander

2017-02-01

Replicate composite bones are used extensively for in vitro testing of new orthopedic devices. Contrary to tests with cadaveric bone material, which inherently exhibits large variability, they offer a standardized alternative with limited variability. Accurate knowledge of the composite's material properties is important when interpreting in vitro test results and when using them in FE models of biomechanical constructs. The cortical bone analogue material properties of three different fourth-generation composite bone models were determined by updating FE bone models using experimental and numerical modal analyses results. The influence of the cortical bone analogue material model (isotropic or transversely isotropic) and the inter- and intra-specimen variability were assessed. Isotropic cortical bone analogue material models failed to represent the experimental behavior in a satisfactory way even after updating the elastic material constants. When transversely isotropic material models were used, the updating procedure resulted in a reduction of the longitudinal Young's modulus from 16.00GPa before updating to an average of 13.96 GPa after updating. The shear modulus was increased from 3.30GPa to an average value of 3.92GPa. The transverse Young's modulus was lowered from an initial value of 10.00GPa to 9.89GPa. Low inter- and intra-specimen variability was found. Copyright © 2016 Elsevier Ltd. All rights reserved.

FY2017 Updates to the SAS4A/SASSYS-1 Safety Analysis Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fanning, T. H.

The SAS4A/SASSYS-1 safety analysis software is used to perform deterministic analysis of anticipated events as well as design-basis and beyond-design-basis accidents for advanced fast reactors. It plays a central role in the analysis of U.S. DOE conceptual designs, proposed test and demonstration reactors, and in domestic and international collaborations. This report summarizes the code development activities that have taken place during FY2017. Extensions to the void and cladding reactivity feedback models have been implemented, and Control System capabilities have been improved through a new virtual data acquisition system for plant state variables and an additional Block Signal for a variablemore » lag compensator to represent reactivity feedback for novel shutdown devices. Current code development and maintenance needs are also summarized in three key areas: software quality assurance, modeling improvements, and maintenance of related tools. With ongoing support, SAS4A/SASSYS-1 can continue to fulfill its growing role in fast reactor safety analysis and help solidify DOE’s leadership role in fast reactor safety both domestically and in international collaborations.« less

Approximating Fluid Flow from Ambient to Very Low Pressures: Modeling ISS Experiments that Vent to Vacuum

NASA Technical Reports Server (NTRS)

Minor, Robert

2002-01-01

Two ISS (International Space Station) experiment payloads will vent a volume of gas overboard via either the ISS Vacuum Exhaust System or the Vacuum Resource System. A system of ducts, valves and sensors, under design, will connect the experiments to the ISS systems. The following tasks are required: Create an analysis tool that will verify the rack vacuum system design with respect to design requirements, more specifically approximate pressure at given locations within the vacuum systems; Determine the vent duration required to achieve desired pressure within the experiment modules; Update the analysis as systems and operations definitions mature.

Cortical oscillations and sensory predictions.

PubMed

Arnal, Luc H; Giraud, Anne-Lise

2012-07-01

Many theories of perception are anchored in the central notion that the brain continuously updates an internal model of the world to infer the probable causes of sensory events. In this framework, the brain needs not only to predict the causes of sensory input, but also when they are most likely to happen. In this article, we review the neurophysiological bases of sensory predictions of "what' (predictive coding) and 'when' (predictive timing), with an emphasis on low-level oscillatory mechanisms. We argue that neural rhythms offer distinct and adapted computational solutions to predicting 'what' is going to happen in the sensory environment and 'when'. Copyright © 2012 Elsevier Ltd. All rights reserved.

Estimates of internal-dose equivalent from inhalation and ingestion of selected radionuclides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunning, D.E.

1982-01-01

This report presents internal radiation dose conversion factors for radionuclides of interest in environmental assessments of nuclear fuel cycles. This volume provides an updated summary of estimates of committed dose equivalent for radionuclides considered in three previous Oak Ridge National Laboratory (ORNL) reports. Intakes by inhalation and ingestion are considered. The International Commission on Radiological Protection (ICRP) Task Group Lung Model has been used to simulate the deposition and retention of particulate matter in the respiratory tract. Results corresponding to activity median aerodynamic diameters (AMAD) of 0.3, 1.0, and 5.0 ..mu..m are given. The gastorintestinal (GI) tract has been representedmore » by a four-segment catenary model with exponential transfer of radioactivity from one segment to the next. Retention of radionuclides in systemic organs is characterized by linear combinations of decaying exponential functions, recommended in ICRP Publication 30. The first-year annual dose rate, maximum annual dose rate, and fifty-year dose commitment per microcurie intake of each radionuclide is given for selected target organs and the effective dose equivalent. These estimates include contributions from specified source organs plus the systemic activity residing in the rest of the body; cross irradiation due to penetrating radiations has been incorporated into these estimates. 15 references.« less

Vestibular stimulation interferes with the dynamics of an internal representation of gravity.

PubMed

De Sá Teixeira, Nuno Alexandre; Hecht, Heiko; Diaz Artiles, Ana; Seyedmadani, Kimia; Sherwood, David P; Young, Laurence R

2017-11-01

The remembered vanishing location of a moving target has been found to be displaced downward in the direction of gravity (representational gravity) and more so with increasing retention intervals, suggesting that the visual spatial updating recruits an internal model of gravity. Despite being consistently linked with gravity, few inquiries have been made about the role of vestibular information in these trends. Previous experiments with static tilting of observers' bodies suggest that under conflicting cues between the idiotropic vector and vestibular signals, the dynamic drift in memory is reduced to a constant displacement along the body's main axis. The present experiment aims to replicate and extend these outcomes while keeping the observers' bodies unchanged in relation to physical gravity by varying the gravito-inertial acceleration using a short-radius centrifuge. Observers were shown, while accelerated to varying degrees, targets moving along several directions and were required to indicate the perceived vanishing location after a variable interval. Increases of the gravito-inertial force (up to 1.4G), orthogonal to the idiotropic vector, did not affect the direction of representational gravity, but significantly disrupted its time course. The role and functioning of an internal model of gravity for spatial perception and orientation are discussed in light of the results.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peter H. Israelsson; E. Eric Adams

On December 4, 1997, the US Department of Energy (USDOE), the New Energy and Industrial Technology Development Organization of Japan (NEDO), and the Norwegian Research Council (NRC) entered into a Project Agreement for International Collaboration on CO{sub 2} Ocean Sequestration. Government organizations from Japan, Canada, and Australia, and a Swiss/Swedish engineering firm later joined the agreement, which outlined a research strategy for ocean carbon sequestration via direct injection. The members agreed to an initial field experiment, with the hope that if the initial experiment was successful, there would be subsequent field evaluations of increasingly larger scale to evaluate environmental impactsmore » of sequestration and the potential for commercialization. The evolution of the collaborative effort, the supporting research, and results for the International Collaboration on CO{sub 2} Ocean Sequestration were documented in almost 100 papers and reports, including 18 peer-reviewed journal articles, 46 papers, 28 reports, and 4 graduate theses. These efforts were summarized in our project report issued January 2005 and covering the period August 23, 1998-October 23, 2004. An accompanying CD contained electronic copies of all the papers and reports. This report focuses on results of a two-year sub-task to update an environmental assessment of acute marine impacts resulting from direct ocean sequestration. The approach is based on the work of Auerbach et al. [6] and Caulfield et al. [20] to assess mortality to zooplankton, but uses updated information concerning bioassays, an updated modeling approach and three modified injection scenarios: a point release of negatively buoyant solid CO{sub 2} hydrate particles from a moving ship; a long, bottom-mounted diffuser discharging buoyant liquid CO{sub 2} droplets; and a stationary point release of hydrate particles forming a sinking plume. Results suggest that in particular the first two discharge modes could be successfully designed to largely avoid zooplankton mortality. Sub-lethal and ecosystem effects are discussed qualitatively, but not analyzed quantitatively.« less

Highlights from the 10th Breast, Gynaecological and Immunotherapy International Cancer Conference (BGICC), 18-19 January 2018, Cairo, Egypt.

PubMed

El-Ghazaly, Hesham; Aref, Adel; Bahie-Eldin, Nermeen

2018-01-01

During the 10th Breast, Gynaecological and Immunotherapy International Cancer Conference (BGICC), which was held on 18 and 19 of January, 2018, in Cairo, Egypt, around 100 international, regional and national experts presented the latest updates in breast cancer, gynaecological cancers and immunotherapy in oncology. Through this report, we will try to highlight the important data and consensus issues that were discussed during the conference.

Iraq’s Debt Relief: Procedure and Potential Implications for International Debt Relief

DTIC Science & Technology

2008-10-02

Order Code RL33376 Iraq’s Debt Relief: Procedure and Potential Implications for International Debt Relief Updated October 2, 2008 Martin A. Weiss...4. TITLE AND SUBTITLE Iraq?s Debt Relief: Procedure and Potential Implications for International Debt Relief 5a. CONTRACT NUMBER 5b. GRANT NUMBER...b. ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 Iraq’s Debt Relief: Procedure

Canadian Naval Fire Support for Land Operations Conceptual Overview

DTIC Science & Technology

2014-09-08

wide variety of domestic and international operations.”2 In the 1990s, the Iroquois class mid-life conversion through the Tribal Update and...defence on the other.”7 Within the context of an ever-changing international environment, the CFDS outlines six core missions for the CAF. Of...particular interest to NFS is mission 5: “Lead and/or conduct a major international operation for an extended period.”8 The Government has indicated that

Update From the 2011 International Schwannomatosis Workshop: From Genetics to Diagnostic Criteria

PubMed Central

Plotkin, Scott R.; Blakeley, Jaishri O.; Evans, D. Gareth; Hanemann, C. Oliver; Hulsebos, Theo J.M.; Hunter-Schaedle, Kim; Kalpana, Ganjam V.; Korf, Bruce; Messiaen, Ludwine; Papi, Laura; Ratner, Nancy; Sherman, Larry S.; Smith, Miriam J.; Stemmer-Rachamimov, Anat O.; Vitte, Jeremie; Giovannini, Marco

2014-01-01

Schwannomatosis is the third major form of neurofibromatosis and is characterized by the development of multiple schwannomas in the absence of bilateral vestibular schwannomas. The 2011 Schwannomatosis Update was organized by the Children’s Tumor Foundation (www.ctf.org) and held in Los Angeles, CA, from June 5–8, 2011. This article summarizes the highlights presented at the Conference and represents the “state-of-the-field” in 2011. Genetic studies indicate that constitutional mutations in the SMARCB1 tumor suppressor gene occur in 40–50% of familial cases and in 8–10% of sporadic cases of schwannomatosis. Tumorigenesis is thought to occur through a four-hit, three-step model, beginning with a germline mutation in SMARCB1 (hit 1), followed by loss of a portion of chromosome 22 that contains the second SMARCB1 allele and one NF2 allele (hits 2 and 3), followed by mutation of the remaining wild-type NF2 allele (hit 4). Insights from research on HIV and pediatric rhabdoid tumors have shed light on potential molecular pathways that are dysregulated in schwannomatosis-related schwannomas. Mouse models of schwannomatosis have been developed and promise to further expand our understanding of tumorigenesis and the tumor microenvironment. Clinical reports have described the occurrence of intracranial meningiomas in schwannomatosis patients and in families with germline SMARCB1 mutations. The authors propose updated diagnostic criteria to incorporate new clinical and genetic findings since 2005. In the next 5 years, the authors expect that advances in basic research in the pathogenesis of schwannomatosis will lead toward clinical investigations of potential drug therapies. PMID:23401320

The AFIS tree growth model for updating annual forest inventories in Minnesota

Treesearch

Margaret R. Holdaway

2000-01-01

As the Forest Service moves towards annual inventories, states may use model predictions of growth to update unmeasured plots. A tree growth model (AFIS) based on the scaled Weibull function and using the average-adjusted model form is presented. Annual diameter growth for four species was modeled using undisturbed plots from Minnesota's Aspen-Birch and Northern...

Uncertainty aggregation and reduction in structure-material performance prediction

NASA Astrophysics Data System (ADS)

Hu, Zhen; Mahadevan, Sankaran; Ao, Dan

2018-02-01

An uncertainty aggregation and reduction framework is presented for structure-material performance prediction. Different types of uncertainty sources, structural analysis model, and material performance prediction model are connected through a Bayesian network for systematic uncertainty aggregation analysis. To reduce the uncertainty in the computational structure-material performance prediction model, Bayesian updating using experimental observation data is investigated based on the Bayesian network. It is observed that the Bayesian updating results will have large error if the model cannot accurately represent the actual physics, and that this error will be propagated to the predicted performance distribution. To address this issue, this paper proposes a novel uncertainty reduction method by integrating Bayesian calibration with model validation adaptively. The observation domain of the quantity of interest is first discretized into multiple segments. An adaptive algorithm is then developed to perform model validation and Bayesian updating over these observation segments sequentially. Only information from observation segments where the model prediction is highly reliable is used for Bayesian updating; this is found to increase the effectiveness and efficiency of uncertainty reduction. A composite rotorcraft hub component fatigue life prediction model, which combines a finite element structural analysis model and a material damage model, is used to demonstrate the proposed method.

Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology

PubMed Central

Brudey, Karine; Driscoll, Jeffrey R; Rigouts, Leen; Prodinger, Wolfgang M; Gori, Andrea; Al-Hajoj, Sahal A; Allix, Caroline; Aristimuño, Liselotte; Arora, Jyoti; Baumanis, Viesturs; Binder, Lothar; Cafrune, Patricia; Cataldi, Angel; Cheong, Soonfatt; Diel, Roland; Ellermeier, Christopher; Evans, Jason T; Fauville-Dufaux, Maryse; Ferdinand, Séverine; de Viedma, Dario Garcia; Garzelli, Carlo; Gazzola, Lidia; Gomes, Harrison M; Guttierez, M Cristina; Hawkey, Peter M; van Helden, Paul D; Kadival, Gurujaj V; Kreiswirth, Barry N; Kremer, Kristin; Kubin, Milan; Kulkarni, Savita P; Liens, Benjamin; Lillebaek, Troels; Ly, Ho Minh; Martin, Carlos; Martin, Christian; Mokrousov, Igor; Narvskaïa, Olga; Ngeow, Yun Fong; Naumann, Ludmilla; Niemann, Stefan; Parwati, Ida; Rahim, Zeaur; Rasolofo-Razanamparany, Voahangy; Rasolonavalona, Tiana; Rossetti, M Lucia; Rüsch-Gerdes, Sabine; Sajduda, Anna; Samper, Sofia; Shemyakin, Igor G; Singh, Urvashi B; Somoskovi, Akos; Skuce, Robin A; van Soolingen, Dick; Streicher, Elisabeth M; Suffys, Philip N; Tortoli, Enrico; Tracevska, Tatjana; Vincent, Véronique; Victor, Tommie C; Warren, Robin M; Yap, Sook Fan; Zaman, Khadiza; Portaels, Françoise; Rastogi, Nalin; Sola, Christophe

2006-01-01

Background The Direct Repeat locus of the Mycobacterium tuberculosis complex (MTC) is a member of the CRISPR (Clustered regularly interspaced short palindromic repeats) sequences family. Spoligotyping is the widely used PCR-based reverse-hybridization blotting technique that assays the genetic diversity of this locus and is useful both for clinical laboratory, molecular epidemiology, evolutionary and population genetics. It is easy, robust, cheap, and produces highly diverse portable numerical results, as the result of the combination of (1) Unique Events Polymorphism (UEP) (2) Insertion-Sequence-mediated genetic recombination. Genetic convergence, although rare, was also previously demonstrated. Three previous international spoligotype databases had partly revealed the global and local geographical structures of MTC bacilli populations, however, there was a need for the release of a new, more representative and extended, international spoligotyping database. Results The fourth international spoligotyping database, SpolDB4, describes 1939 shared-types (STs) representative of a total of 39,295 strains from 122 countries, which are tentatively classified into 62 clades/lineages using a mixed expert-based and bioinformatical approach. The SpolDB4 update adds 26 new potentially phylogeographically-specific MTC genotype families. It provides a clearer picture of the current MTC genomes diversity as well as on the relationships between the genetic attributes investigated (spoligotypes) and the infra-species classification and evolutionary history of the species. Indeed, an independent Naïve-Bayes mixture-model analysis has validated main of the previous supervised SpolDB3 classification results, confirming the usefulness of both supervised and unsupervised models as an approach to understand MTC population structure. Updated results on the epidemiological status of spoligotypes, as well as genetic prevalence maps on six main lineages are also shown. Our results suggests the existence of fine geographical genetic clines within MTC populations, that could mirror the passed and present Homo sapiens sapiens demographical and mycobacterial co-evolutionary history whose structure could be further reconstructed and modelled, thereby providing a large-scale conceptual framework of the global TB Epidemiologic Network. Conclusion Our results broaden the knowledge of the global phylogeography of the MTC complex. SpolDB4 should be a very useful tool to better define the identity of a given MTC clinical isolate, and to better analyze the links between its current spreading and previous evolutionary history. The building and mining of extended MTC polymorphic genetic databases is in progress. PMID:16519816

NRL/VOA Modifications to IONCAP as of 12 July 1988

DTIC Science & Technology

1989-08-02

suitable for wide-area coverage studies), to incorporate a newer noise model , to improve the accuracy of some calculations, to correct a few...with IONANT ............................................................... 13 C. Incorporation of an Updated Noise Model into IONCAP...LISTINGS OF FOUR IONCAP SUBROUTINES SUPPORTING THE UPDATED NOISE MODEL ................................................................... 42 VI. LISTING

Incremental Testing of the Community Multiscale Air Quality (CMAQ) Modeling System Version 4.7

EPA Science Inventory

This paper describes the scientific and structural updates to the latest release of the Community Multiscale Air Quality (CMAQ) modeling system version 4.7 (v4.7) and points the reader to additional resources for further details. The model updates were evaluated relative to obse...

Enumeration and extension of non-equivalent deterministic update schedules in Boolean networks.

PubMed

Palma, Eduardo; Salinas, Lilian; Aracena, Julio

2016-03-01

Boolean networks (BNs) are commonly used to model genetic regulatory networks (GRNs). Due to the sensibility of the dynamical behavior to changes in the updating scheme (order in which the nodes of a network update their state values), it is increasingly common to use different updating rules in the modeling of GRNs to better capture an observed biological phenomenon and thus to obtain more realistic models.In Aracena et al. equivalence classes of deterministic update schedules in BNs, that yield exactly the same dynamical behavior of the network, were defined according to a certain label function on the arcs of the interaction digraph defined for each scheme. Thus, the interaction digraph so labeled (update digraphs) encode the non-equivalent schemes. We address the problem of enumerating all non-equivalent deterministic update schedules of a given BN. First, we show that it is an intractable problem in general. To solve it, we first construct an algorithm that determines the set of update digraphs of a BN. For that, we use divide and conquer methodology based on the structural characteristics of the interaction digraph. Next, for each update digraph we determine a scheme associated. This algorithm also works in the case where there is a partial knowledge about the relative order of the updating of the states of the nodes. We exhibit some examples of how the algorithm works on some GRNs published in the literature. An executable file of the UpdateLabel algorithm made in Java and the files with the outputs of the algorithms used with the GRNs are available at: www.inf.udec.cl/ ∼lilian/UDE/ CONTACT: lilisalinas@udec.cl Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Visiting Vehicle Ground Trajectory Tool

NASA Technical Reports Server (NTRS)

Hamm, Dustin

2013-01-01

The International Space Station (ISS) Visiting Vehicle Group needed a targeting tool for vehicles that rendezvous with the ISS. The Visiting Vehicle Ground Trajectory targeting tool provides the ability to perform both realtime and planning operations for the Visiting Vehicle Group. This tool provides a highly reconfigurable base, which allows the Visiting Vehicle Group to perform their work. The application is composed of a telemetry processing function, a relative motion function, a targeting function, a vector view, and 2D/3D world map type graphics. The software tool provides the ability to plan a rendezvous trajectory for vehicles that visit the ISS. It models these relative trajectories using planned and realtime data from the vehicle. The tool monitors ongoing rendezvous trajectory relative motion, and ensures visiting vehicles stay within agreed corridors. The software provides the ability to update or re-plan a rendezvous to support contingency operations. Adding new parameters and incorporating them into the system was previously not available on-the-fly. If an unanticipated capability wasn't discovered until the vehicle was flying, there was no way to update things.

Overview and Evaluation of the Community Multiscale Air Quality (CMAQ) Modeling System Version 5.2

EPA Science Inventory

A new version of the Community Multiscale Air Quality (CMAQ) model, version 5.2 (CMAQv5.2), is currently being developed, with a planned release date in 2017. The new model includes numerous updates from the previous version of the model (CMAQv5.1). Specific updates include a new...

Application of firefly algorithm to the dynamic model updating problem

NASA Astrophysics Data System (ADS)

Shabbir, Faisal; Omenzetter, Piotr

2015-04-01

Model updating can be considered as a branch of optimization problems in which calibration of the finite element (FE) model is undertaken by comparing the modal properties of the actual structure with these of the FE predictions. The attainment of a global solution in a multi dimensional search space is a challenging problem. The nature-inspired algorithms have gained increasing attention in the previous decade for solving such complex optimization problems. This study applies the novel Firefly Algorithm (FA), a global optimization search technique, to a dynamic model updating problem. This is to the authors' best knowledge the first time FA is applied to model updating. The working of FA is inspired by the flashing characteristics of fireflies. Each firefly represents a randomly generated solution which is assigned brightness according to the value of the objective function. The physical structure under consideration is a full scale cable stayed pedestrian bridge with composite bridge deck. Data from dynamic testing of the bridge was used to correlate and update the initial model by using FA. The algorithm aimed at minimizing the difference between the natural frequencies and mode shapes of the structure. The performance of the algorithm is analyzed in finding the optimal solution in a multi dimensional search space. The paper concludes with an investigation of the efficacy of the algorithm in obtaining a reference finite element model which correctly represents the as-built original structure.

A model-updating procedure to stimulate piezoelectric transducers accurately.

PubMed

Piranda, B; Ballandras, S; Steichen, W; Hecart, B

2001-09-01

The use of numerical calculations based on finite element methods (FEM) has yielded significant improvements in the simulation and design of piezoelectric transducers piezoelectric transducer utilized in acoustic imaging. However, the ultimate precision of such models is directly controlled by the accuracy of material characterization. The present work is dedicated to the development of a model-updating technique adapted to the problem of piezoelectric transducer. The updating process is applied using the experimental admittance of a given structure for which a finite element analysis is performed. The mathematical developments are reported and then applied to update the entries of a FEM of a two-layer structure (a PbZrTi-PZT-ridge glued on a backing) for which measurements were available. The efficiency of the proposed approach is demonstrated, yielding the definition of a new set of constants well adapted to predict the structure response accurately. Improvement of the proposed approach, consisting of the updating of material coefficients not only on the admittance but also on the impedance data, is finally discussed.

Updating sea spray aerosol emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2

NASA Astrophysics Data System (ADS)

Gantt, B.; Kelly, J. T.; Bash, J. O.

2015-11-01

Sea spray aerosols (SSAs) impact the particle mass concentration and gas-particle partitioning in coastal environments, with implications for human and ecosystem health. Model evaluations of SSA emissions have mainly focused on the global scale, but regional-scale evaluations are also important due to the localized impact of SSAs on atmospheric chemistry near the coast. In this study, SSA emissions in the Community Multiscale Air Quality (CMAQ) model were updated to enhance the fine-mode size distribution, include sea surface temperature (SST) dependency, and reduce surf-enhanced emissions. Predictions from the updated CMAQ model and those of the previous release version, CMAQv5.0.2, were evaluated using several coastal and national observational data sets in the continental US. The updated emissions generally reduced model underestimates of sodium, chloride, and nitrate surface concentrations for coastal sites in the Bay Regional Atmospheric Chemistry Experiment (BRACE) near Tampa, Florida. Including SST dependency to the SSA emission parameterization led to increased sodium concentrations in the southeastern US and decreased concentrations along parts of the Pacific coast and northeastern US. The influence of sodium on the gas-particle partitioning of nitrate resulted in higher nitrate particle concentrations in many coastal urban areas due to increased condensation of nitric acid in the updated simulations, potentially affecting the predicted nitrogen deposition in sensitive ecosystems. Application of the updated SSA emissions to the California Research at the Nexus of Air Quality and Climate Change (CalNex) study period resulted in a modest improvement in the predicted surface concentration of sodium and nitrate at several central and southern California coastal sites. This update of SSA emissions enabled a more realistic simulation of the atmospheric chemistry in coastal environments where marine air mixes with urban pollution.

Kennedy Space Center Director Update

NASA Image and Video Library

2014-03-06

CAPE CANAVERAL, Fla. - NASA Kennedy Space Center Director Robert Cabana, second from right, welcomes community leaders, business executives, educators, community organizers, and state and local government leaders to the Kennedy Space Center Visitor Complex Debus Center for the Kennedy Space Center Director Update. At far right is Brevard County District 1 Commissioner Robin Fisher. Attendees talked with Cabana and other senior Kennedy managers and visited displays featuring updates on Kennedy programs and projects, including International Space Station, Commercial Crew, Ground System Development and Operations, Launch Services, Center Planning and Development, Technology, KSC Swamp Works and NASA Education. The morning concluded with a tour of the new Space Shuttle Atlantis exhibit at the visitor complex. For more information, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Daniel Casper

Nuclear Decay Data for the International Reactor Dosimetry Library for Fission and Fusion (IRDFF): Updated Evaluations of the Half-Lives and Gamma Ray Intensities

NASA Astrophysics Data System (ADS)

Chechev, Valery P.; Kuzmenko, Nikolay K.

2016-02-01

Updated evaluations of the half-lives and prominent gamma ray intensities have been presented for 20 radionuclides - dosimetry reaction residuals. The new values of these decay characteristics recommended for the IRDFF library were obtained using the approaches and methodology adopted by the working group of the Decay Data Evaluation Project (DDEP) cooperation. The experimental data published up to 2014 were taken into account in updated evaluations. The list of radionuclides includes 3H, 18F, 22Na, 24Na, 46Sc, 51Cr, 54Mn, 59Fe, 57Co, 60Co, 57Ni, 64Cu, 88Y, 132Te, 131I, 140Ba, 140La, 141Ce, 182Ta, 198Au.

Wisconsin's forest statistics, 1987: an inventory update.

Treesearch

W. Brad Smith; Jerold T. Hahn

1989-01-01

The Wisconsin 1987 inventory update, derived by using tree growth models, reports 14.7 million acres of timberland, a decline of less than 1% since 1983. This bulletin presents findings from the inventory update in tables detailing timberland area, volume, and biomass.

Stabilizing Motifs in Autonomous Boolean Networks and the Yeast Cell Cycle Oscillator

NASA Astrophysics Data System (ADS)

Sevim, Volkan; Gong, Xinwei; Socolar, Joshua

2009-03-01

Synchronously updated Boolean networks are widely used to model gene regulation. Some properties of these model networks are known to be artifacts of the clocking in the update scheme. Autonomous updating is a less artificial scheme that allows one to introduce small timing perturbations and study stability of the attractors. We argue that the stabilization of a limit cycle in an autonomous Boolean network requires a combination of motifs such as feed-forward loops and auto-repressive links that can correct small fluctuations in the timing of switching events. A recently published model of the transcriptional cell-cycle oscillator in yeast contains the motifs necessary for stability under autonomous updating [1]. [1] D. A. Orlando, et al. Nature (London), 4530 (7197):0 944--947, 2008.

International Approaches to Renewable Energy Education--A Faculty Professional Development Case Study with Recommended Practices for STEM Educators

ERIC Educational Resources Information Center

Walz, Kenneth A.; Slowinski, Mary; Alfano, Kathleen

2016-01-01

Calls for increased international competency in U.S. college graduates and the global nature of the renewable energy industry require an exploration of how to incorporate a global perspective in STEM curricula, and how to best develop faculty providing them with global knowledge and skills necessary to update and improve existing teaching…

NIST/ASME Steam Properties Database

National Institute of Standards and Technology Data Gateway

SRD 10 NIST/ASME Steam Properties Database (PC database for purchase)   Based upon the International Association for the Properties of Water and Steam (IAPWS) 1995 formulation for the thermodynamic properties of water and the most recent IAPWS formulations for transport and other properties, this updated version provides water properties over a wide range of conditions according to the accepted international standards.

Beyond the Mincer Equation: The Internal Rate of Return to Higher Education in Colombia

ERIC Educational Resources Information Center

García-Suaza, Andrés Felipe; Guataquí, Juan Carlos; Guerra, José Alberto; Maldonado, Darío

2014-01-01

In order to present an estimation of the internal rate of return (IRR) to higher education in Colombia, we take advantage of recent updates on the methodological approach towards earnings equations. In order to overcome the criticism that surrounds interpretations of the education coefficient of Mincer equations as being the rate of return to…

A Current Analysis of the Treatment of Japanese Americans and Internment in United States History Textbooks

ERIC Educational Resources Information Center

Hawkins, Jeffrey M.; Buckendorf, Michael

2010-01-01

A content analysis of ten United States history textbooks (2005-2008) was conducted by the researchers to determine the current depiction of Japanese Americans and internment during the World War II era. This study updates and expands upon the textbooks used in prior research by Romanowski (1995), Harada (2000), and Ogawa (2004) that had numerous…

Ear infection - acute

MedlinePlus

... more than 6 children) Changes in altitude or climate Cold climate Exposure to smoke Family history of ear infections ... Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Internal review and update ...

Using Four Downscaling Techniques to Characterize Uncertainty in Updating Intensity-Duration-Frequency Curves Under Climate Change

NASA Astrophysics Data System (ADS)

Cook, L. M.; Samaras, C.; McGinnis, S. A.

2017-12-01

Intensity-duration-frequency (IDF) curves are a common input to urban drainage design, and are used to represent extreme rainfall in a region. As rainfall patterns shift into a non-stationary regime as a result of climate change, these curves will need to be updated with future projections of extreme precipitation. Many regions have begun to update these curves to reflect the trends from downscaled climate models; however, few studies have compared the methods for doing so, as well as the uncertainty that results from the selection of the native grid scale and temporal resolution of the climate model. This study examines the variability in updated IDF curves for Pittsburgh using four different methods for adjusting gridded regional climate model (RCM) outputs into station scale precipitation extremes: (1) a simple change factor applied to observed return levels, (2) a naïve adjustment of stationary and non-stationary Generalized Extreme Value (GEV) distribution parameters, (3) a transfer function of the GEV parameters from the annual maximum series, and (4) kernel density distribution mapping bias correction of the RCM time series. Return level estimates (rainfall intensities) and confidence intervals from these methods for the 1-hour to 48-hour duration are tested for sensitivity to the underlying spatial and temporal resolution of the climate ensemble from the NA-CORDEX project, as well as, the future time period for updating. The first goal is to determine if uncertainty is highest for: (i) the downscaling method, (ii) the climate model resolution, (iii) the climate model simulation, (iv) the GEV parameters, or (v) the future time period examined. Initial results of the 6-hour, 10-year return level adjusted with the simple change factor method using four climate model simulations of two different spatial resolutions show that uncertainty is highest in the estimation of the GEV parameters. The second goal is to determine if complex downscaling methods and high-resolution climate models are necessary for updating, or if simpler methods and lower resolution climate models will suffice. The final results can be used to inform the most appropriate method and climate model resolutions to use for updating IDF curves for urban drainage design.

The International DORIS Service (IDS) - Recent Developments in Preparation for ITRF2013

NASA Technical Reports Server (NTRS)

Willis, Pascal; Lemoine, Frank G.; Moreaux, Guilhem; Soudarin, Laurent; Ferrage, Pascale; Ries, John; Otten, Michiel; Saunier, Jerome; Noll, Carey E.; Biancale, Richard;

Updated aerosol module and its application to simulate secondary organic aerosols during IMPACT campaign May 2008

NASA Astrophysics Data System (ADS)

Li, Y. P.; Elbern, H.; Lu, K. D.; Friese, E.; Kiendler-Scharr, A.; Mentel, Th. F.; Wang, X. S.; Wahner, A.; Zhang, Y. H.

2013-03-01

The formation of Secondary organic aerosol (SOA) was simulated with the Secondary ORGanic Aerosol Model (SORGAM) by a classical gas-particle partitioning concept, using the two-product model approach, which is widely used in chemical transport models. In this study, we extensively updated SORGAM including three major modifications: firstly, we derived temperature dependence functions of the SOA yields for aromatics and biogenic VOCs, based on recent chamber studies within a sophisticated mathematic optimization framework; secondly, we implemented the SOA formation pathways from photo oxidation (OH initiated) of isoprene; thirdly, we implemented the SOA formation channel from NO3-initiated oxidation of reactive biogenic hydrocarbons (isoprene and monoterpenes). The temperature dependence functions of the SOA yields were validated against available chamber experiments. Moreover, the whole updated SORGAM module was validated against ambient SOA observations represented by the summed oxygenated organic aerosol (OOA) concentrations abstracted from Aerosol Mass Spectrometer (AMS) measurements at a rural site near Rotterdam, the Netherlands, performed during the IMPACT campaign in May 2008. In this case, we embedded both the original and the updated SORGAM module into the EURopean Air pollution and Dispersion-Inverse Model (EURAD-IM), which showed general good agreements with the observed meteorological parameters and several secondary products such as O3, sulfate and nitrate. With the updated SORGAM module, the EURAD-IM model also captured the observed SOA concentrations reasonably well especially those during nighttime. In contrast, the EURAD-IM model before update underestimated the observations by a factor of up to 5. The large improvements of the modeled SOA concentrations by updated SORGAM were attributed to the mentioned three modifications. Embedding the temperature dependence functions of the SOA yields, including the new pathways from isoprene photo oxidations, and switching on the SOA formation from NO3 initiated biogenic VOCs oxidations contributed to this enhancement by 10%, 22% and 47%, respectively. However, the EURAD-IM model with updated SORGAM still clearly underestimated the afternoon SOA observations up to a factor of two. More work such as to improve the simulated OH concentrations under high VOCs and low NOx concentrations, further including the SOA formation from semi-volatile organic compounds, the correct aging process of aerosols, oligomerization process and the influence on the biogenic SOA by the anthropogenic SOA, are still required to fill the gap.

Crucial role of strategy updating for coexistence of strategies in interaction networks.

PubMed

Zhang, Jianlei; Zhang, Chunyan; Cao, Ming; Weissing, Franz J

2015-04-01

Network models are useful tools for studying the dynamics of social interactions in a structured population. After a round of interactions with the players in their local neighborhood, players update their strategy based on the comparison of their own payoff with the payoff of one of their neighbors. Here we show that the assumptions made on strategy updating are of crucial importance for the strategy dynamics. In the first step, we demonstrate that seemingly small deviations from the standard assumptions on updating have major implications for the evolutionary outcome of two cooperation games: cooperation can more easily persist in a Prisoner's Dilemma game, while it can go more easily extinct in a Snowdrift game. To explain these outcomes, we develop a general model for the updating of states in a network that allows us to derive conditions for the steady-state coexistence of states (or strategies). The analysis reveals that coexistence crucially depends on the number of agents consulted for updating. We conclude that updating rules are as important for evolution on a network as network structure and the nature of the interaction.

Crucial role of strategy updating for coexistence of strategies in interaction networks

NASA Astrophysics Data System (ADS)

Zhang, Jianlei; Zhang, Chunyan; Cao, Ming; Weissing, Franz J.

2015-04-01

Network models are useful tools for studying the dynamics of social interactions in a structured population. After a round of interactions with the players in their local neighborhood, players update their strategy based on the comparison of their own payoff with the payoff of one of their neighbors. Here we show that the assumptions made on strategy updating are of crucial importance for the strategy dynamics. In the first step, we demonstrate that seemingly small deviations from the standard assumptions on updating have major implications for the evolutionary outcome of two cooperation games: cooperation can more easily persist in a Prisoner's Dilemma game, while it can go more easily extinct in a Snowdrift game. To explain these outcomes, we develop a general model for the updating of states in a network that allows us to derive conditions for the steady-state coexistence of states (or strategies). The analysis reveals that coexistence crucially depends on the number of agents consulted for updating. We conclude that updating rules are as important for evolution on a network as network structure and the nature of the interaction.

Preface: Current perspectives in modelling, monitoring, and predicting geophysical fluid dynamics

NASA Astrophysics Data System (ADS)

Mancho, Ana M.; Hernández-García, Emilio; López, Cristóbal; Turiel, Antonio; Wiggins, Stephen; Pérez-Muñuzuri, Vicente

2018-02-01

The third edition of the international workshop Nonlinear Processes in Oceanic and Atmospheric Flows was held at the Institute of Mathematical Sciences (ICMAT) in Madrid from 6 to 8 July 2016. The event gathered oceanographers, atmospheric scientists, physicists, and applied mathematicians sharing a common interest in the nonlinear dynamics of geophysical fluid flows. The philosophy of this meeting was to bring together researchers from a variety of backgrounds into an environment that favoured a vigorous discussion of concepts across different disciplines. The present Special Issue on Current perspectives in modelling, monitoring, and predicting geophysical fluid dynamics contains selected contributions, mainly from attendants of the workshop, providing an updated perspective on modelling aspects of geophysical flows as well as issues on prediction and assimilation of observational data and novel tools for describing transport and mixing processes in these contexts. More details on these aspects are discussed in this preface.

Space Weather Models and Their Validation and Verification at the CCMC

NASA Technical Reports Server (NTRS)

Hesse, Michael

2010-01-01

The Community Coordinated l\\lodeling Center (CCMC) is a US multi-agency activity with a dual mission. With equal emphasis, CCMC strives to provide science support to the international space research community through the execution of advanced space plasma simulations, and it endeavors to support the space weather needs of the CS and partners. Space weather support involves a broad spectrum, from designing robust forecasting systems and transitioning them to forecasters, to providing space weather updates and forecasts to NASA's robotic mission operators. All of these activities have to rely on validation and verification of models and their products, so users and forecasters have the means to assign confidence levels to the space weather information. In this presentation, we provide an overview of space weather models resident at CCMC, as well as of validation and verification activities undertaken at CCMC or through the use of CCMC services.

The Global Tsunami Model (GTM)

NASA Astrophysics Data System (ADS)

Thio, H. K.; Løvholt, F.; Harbitz, C. B.; Polet, J.; Lorito, S.; Basili, R.; Volpe, M.; Romano, F.; Selva, J.; Piatanesi, A.; Davies, G.; Griffin, J.; Baptista, M. A.; Omira, R.; Babeyko, A. Y.; Power, W. L.; Salgado Gálvez, M.; Behrens, J.; Yalciner, A. C.; Kanoglu, U.; Pekcan, O.; Ross, S.; Parsons, T.; LeVeque, R. J.; Gonzalez, F. I.; Paris, R.; Shäfer, A.; Canals, M.; Fraser, S. A.; Wei, Y.; Weiss, R.; Zaniboni, F.; Papadopoulos, G. A.; Didenkulova, I.; Necmioglu, O.; Suppasri, A.; Lynett, P. J.; Mokhtari, M.; Sørensen, M.; von Hillebrandt-Andrade, C.; Aguirre Ayerbe, I.; Aniel-Quiroga, Í.; Guillas, S.; Macias, J.

2016-12-01

The large tsunami disasters of the last two decades have highlighted the need for a thorough understanding of the risk posed by relatively infrequent but disastrous tsunamis and the importance of a comprehensive and consistent methodology for quantifying the hazard. In the last few years, several methods for probabilistic tsunami hazard analysis have been developed and applied to different parts of the world. In an effort to coordinate and streamline these activities and make progress towards implementing the Sendai Framework of Disaster Risk Reduction (SFDRR) we have initiated a Global Tsunami Model (GTM) working group with the aim of i) enhancing our understanding of tsunami hazard and risk on a global scale and developing standards and guidelines for it, ii) providing a portfolio of validated tools for probabilistic tsunami hazard and risk assessment at a range of scales, and iii) developing a global tsunami hazard reference model. This GTM initiative has grown out of the tsunami component of the Global Assessment of Risk (GAR15), which has resulted in an initial global model of probabilistic tsunami hazard and risk. Started as an informal gathering of scientists interested in advancing tsunami hazard analysis, the GTM is currently in the process of being formalized through letters of interest from participating institutions. The initiative has now been endorsed by the United Nations International Strategy for Disaster Reduction (UNISDR) and the World Bank's Global Facility for Disaster Reduction and Recovery (GFDRR). We will provide an update on the state of the project and the overall technical framework, and discuss the technical issues that are currently being addressed, including earthquake source recurrence models, the use of aleatory variability and epistemic uncertainty, and preliminary results for a probabilistic global hazard assessment, which is an update of the model included in UNISDR GAR15.

The Global Tsunami Model (GTM)

NASA Astrophysics Data System (ADS)

Lorito, S.; Basili, R.; Harbitz, C. B.; Løvholt, F.; Polet, J.; Thio, H. K.

2017-12-01

The tsunamis occurred worldwide in the last two decades have highlighted the need for a thorough understanding of the risk posed by relatively infrequent but often disastrous tsunamis and the importance of a comprehensive and consistent methodology for quantifying the hazard. In the last few years, several methods for probabilistic tsunami hazard analysis have been developed and applied to different parts of the world. In an effort to coordinate and streamline these activities and make progress towards implementing the Sendai Framework of Disaster Risk Reduction (SFDRR) we have initiated a Global Tsunami Model (GTM) working group with the aim of i) enhancing our understanding of tsunami hazard and risk on a global scale and developing standards and guidelines for it, ii) providing a portfolio of validated tools for probabilistic tsunami hazard and risk assessment at a range of scales, and iii) developing a global tsunami hazard reference model. This GTM initiative has grown out of the tsunami component of the Global Assessment of Risk (GAR15), which has resulted in an initial global model of probabilistic tsunami hazard and risk. Started as an informal gathering of scientists interested in advancing tsunami hazard analysis, the GTM is currently in the process of being formalized through letters of interest from participating institutions. The initiative has now been endorsed by the United Nations International Strategy for Disaster Reduction (UNISDR) and the World Bank's Global Facility for Disaster Reduction and Recovery (GFDRR). We will provide an update on the state of the project and the overall technical framework, and discuss the technical issues that are currently being addressed, including earthquake source recurrence models, the use of aleatory variability and epistemic uncertainty, and preliminary results for a probabilistic global hazard assessment, which is an update of the model included in UNISDR GAR15.

The Global Tsunami Model (GTM)

NASA Astrophysics Data System (ADS)

Løvholt, Finn

2017-04-01

The large tsunami disasters of the last two decades have highlighted the need for a thorough understanding of the risk posed by relatively infrequent but disastrous tsunamis and the importance of a comprehensive and consistent methodology for quantifying the hazard. In the last few years, several methods for probabilistic tsunami hazard analysis have been developed and applied to different parts of the world. In an effort to coordinate and streamline these activities and make progress towards implementing the Sendai Framework of Disaster Risk Reduction (SFDRR) we have initiated a Global Tsunami Model (GTM) working group with the aim of i) enhancing our understanding of tsunami hazard and risk on a global scale and developing standards and guidelines for it, ii) providing a portfolio of validated tools for probabilistic tsunami hazard and risk assessment at a range of scales, and iii) developing a global tsunami hazard reference model. This GTM initiative has grown out of the tsunami component of the Global Assessment of Risk (GAR15), which has resulted in an initial global model of probabilistic tsunami hazard and risk. Started as an informal gathering of scientists interested in advancing tsunami hazard analysis, the GTM is currently in the process of being formalized through letters of interest from participating institutions. The initiative has now been endorsed by the United Nations International Strategy for Disaster Reduction (UNISDR) and the World Bank's Global Facility for Disaster Reduction and Recovery (GFDRR). We will provide an update on the state of the project and the overall technical framework, and discuss the technical issues that are currently being addressed, including earthquake source recurrence models, the use of aleatory variability and epistemic uncertainty, and preliminary results for a probabilistic global hazard assessment, which is an update of the model included in UNISDR GAR15.