78 FR 23224 - Fisheries of the South Atlantic; South Atlantic Fishery Management Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

... (AP); Coral AP; Joint Meeting of the Habitat & Environmental Protection AP and Coral AP; and Deepwater.... Coral AP Agenda, Tuesday, May 7, 2013, 1 p.m. Until 5 p.m. 1. Receive an update from NOAA Fisheries Habitat Conservation Division. 2. Receive an update on Coral Nursery Restoration Work and Utilization. 3...

77 FR 56590 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-13

... an information meeting in Seattle, WA on October 2, 2012 on pending rulemaking to revise and update... aisle. DATES: The information meeting will be held from 2:15 p.m. to 5:30 p.m. on October 2, 2012... and any updates to the meeting will be posted on the Access Board's Web site at http://www.access...

Psychophysiology of Delayed Extinction and Reconsolidation in Humans

DTIC Science & Technology

2014-02-01

M., & Soeter, M. (2013). Reconsolidation in a human fear conditioning study: a test of extinction as updating mechanism. Biological Psychology , 92(1...relative strengths of various pharmacological and behavioral, reconsolidation-blocking interventions can be tested . Thus far, we have completed data... test the relative strengths of various reconsolidation-blocking (or memory updating) interventions. In other words, if propranolol or delayed

78 FR 56871 - Environmental Management Site-Specific Advisory Board, Portsmouth

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-16

... Register. DATES: Wednesday, October 2, 2013, 6:00 p.m. ADDRESSES: Ohio State University, Endeavor Center...] Annual Executive Planning and Leadership Training Session Update Subcommittee Updates Election of Chair...

78 FR 69657 - Environmental Management Site-Specific Advisory Board, Portsmouth

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-20

... Register. DATES: Thursday, December 5, 2013, 6:00 p.m. ADDRESSES: Ohio State University, Endeavor Center...] Annual Executive Planning and Leadership Training Session Update [cir] EM National Chairs Meeting Update...

Alternative Fuels Data Center: Maps and Data

Science.gov Websites

acquisitions by fleet type from 1992-2014 Last update August 2016 View Graph Graph Download Data -m8i0e0 Trend of S&FP AFV acquisitions by fuel type from 1992-2015 Last update August 2016 View Graph transactions from 1997-2014 Last update August 2016 View Graph Graph Download Data Generated_thumb20160907

The Navy Precision Optical Interferometer: an update

NASA Astrophysics Data System (ADS)

Armstrong, J. T.; Baines, Ellyn K.; Schmitt, Henrique R.; Restaino, Sergio R.; Clark, James H.; Benson, James A.; Hutter, Donald J.; Zavala, Robert T.; van Belle, Gerard T.

2016-08-01

We describe the current status of the Navy Precision Optical Interferometer (NPOI), including developments since the last SPIE meeting. The NPOI group has added stations as far as 250m from the array center and added numerous infrastructure improvements. Science programs include stellar diameters and limb darkening, binary orbits, Be star disks, exoplanet host stars, and progress toward high-resolution stellar surface imaging. Technical and infrastructure projects include on-sky demonstrations of baseline bootstrapping with six array elements and of the VISION beam combiner, control system updates, integration of the long delay lines, and updated firmware for the Classic beam combiner. Our plans to add up to four 1.8 m telescopes are no longer viable, but we have recently acquired separate funding for adding three 1 m AO-equipped telescopes and an infrared beam combiner to the array.

The link between impaired theory of mind and executive function in children with cerebral palsy.

PubMed

Li, Xiaoming; Wang, Kai; Wu, Jianxian; Hong, Yongfeng; Zhao, Jingpu; Feng, Xiaojun; Xu, Mei; Wang, Min; Ndasauka, Yamikani; Zhang, Xiaochu

2014-07-01

The aim of the study was to explore the relationship between theory of mind (ToM) deficits and executive function (EF) impairments in children with cerebral palsy (CP), 42 CP with children and 42 typically developing (TD) children, acting as controls, were assessed on the tasks of ToM (false belief and faux pas) and EF (inhibition, updating and shifting). Results showed that CP children had deficits both in ToM and EF tasks. The correlation analyses showed that two EF components (inhibition and updating) were strongly related to false belief and faux pas in both two groups. We also found correlation between shifting and false belief and faux pas. However, this correlation was only found in TD children and not in children with CP. These findings suggest that children with CP lag behind TD children in both ToM and EF. Further, the results reveal, interestingly, that ToM deficits in CP children might be related to their inhibition and updating impairments, but not to shifting impairments. Copyright © 2014 Elsevier Ltd. All rights reserved.

77 FR 25686 - Malcolm Baldrige National Quality Award Board of Overseers and Panel of Judges

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-01

..., Baldrige Enterprise Update, Judges Panel Update, Baldrige Fellows Program Discussion, and Strategic Planning. DATES: The meeting will convene on Thursday, June 14, 2012, at 8:30 a.m. Eastern time and adjourn...

Wireless rake-receiver using adaptive filter with a family of partial update algorithms in noise cancellation applications

NASA Astrophysics Data System (ADS)

Fayadh, Rashid A.; Malek, F.; Fadhil, Hilal A.; Aldhaibani, Jaafar A.; Salman, M. K.; Abdullah, Farah Salwani

2015-05-01

For high data rate propagation in wireless ultra-wideband (UWB) communication systems, the inter-symbol interference (ISI), multiple-access interference (MAI), and multiple-users interference (MUI) are influencing the performance of the wireless systems. In this paper, the rake-receiver was presented with the spread signal by direct sequence spread spectrum (DS-SS) technique. The adaptive rake-receiver structure was shown with adjusting the receiver tap weights using least mean squares (LMS), normalized least mean squares (NLMS), and affine projection algorithms (APA) to support the weak signals by noise cancellation and mitigate the interferences. To minimize the data convergence speed and to reduce the computational complexity by the previous algorithms, a well-known approach of partial-updates (PU) adaptive filters were employed with algorithms, such as sequential-partial, periodic-partial, M-max-partial, and selective-partial updates (SPU) in the proposed system. The simulation results of bit error rate (BER) versus signal-to-noise ratio (SNR) are illustrated to show the performance of partial-update algorithms that have nearly comparable performance with the full update adaptive filters. Furthermore, the SPU-partial has closed performance to the full-NLMS and full-APA while the M-max-partial has closed performance to the full-LMS updates algorithms.

Application and Evaluation of MODIS LAI, FPAR, and Albedo ...

EPA Pesticide Factsheets

MODIS vegetation and albedo products provide a more realistic representation of surface conditions for input to the WRF/CMAQ modeling system. However, the initial evaluation of ingesting MODIS data into the system showed mixed results, with increased bias and error for 2-m temperature and reduced bias and error for 2-m mixing ratio. Recently, the WRF/CMAQ land surface and boundary laywer processes have been updated. In this study, MODIS vegetation and albedo data are input to the updated WRF/CMAQ meteorology and air quality simulations for 2006 over a North American (NA) 12-km domain. The evaluation of the simulation results shows that the updated WRF/CMAQ system improves 2-m temperature estimates over the pre-update base modeling system estimates. The MODIS vegetation input produces a realistic spring green-up that progresses through time from the south to north. Overall, MODIS input reduces 2-m mixing ration bias during the growing season. The NA west shows larger positive O3 bias during the growing season because of reduced gas phase deposition resulting from lower O3 deposition velocities driven by reduced vegetation cover. The O3 bias increase associated with the realistic vegetation representation indicates that further improvement may be needed in the WRF/CMAQ system. The National Exposure Research Laboratory’s Atmospheric Modeling Division (AMAD) conducts research in support of EPA’s mission to protect human health and the environment. AMAD’s rese

[Concordance of glomerular filtration rate with creatinine clearance in 24-hour urine and Schwartz and Schwartz updated].

PubMed

Salazar-Gutiérrez, María Luisa; Ochoa-Ponce, Cristina; Lona-Reyes, Juan Carlos; Gutiérrez-Íñiguez, Sara Ivonne

Reference methods for the quantification of the glomerular filtration rate (GFR) are difficult to use in clinical practice; formulas for evaluating GFR based on serum creatinine (SCr) and/or creatinine clearance are used. The aim of this study was to quantify the correlation and concordance of GFR with creatinine clearance in 24-hour urine (GFR24) and Schwartz and Schwartz updated formulas. Cross-sectional study involving healthy pediatric patients and with chronic kidney disease (CKD) from 5 to 16.9 years. Linear correlation between GFR 24 and two formulas was evaluated with the Pearson correlation coefficient (r) and intraclass correlation coefficient (ICC). We studied 134 patients, of which 59.7% were male. Mean age was 10.8 years. The average GFR24 was 140.34ml/min/1.73m 2 ; 34.3% (n=46) had GFR <90ml/min/1.73m 2 . Moderate linear correlation between GFR24 and Schwartz (r= 0.63) and Schwartz updated (r= 0.65) formulas was observed. There was good concordance between the GFR24 and Schwartz (ICC= 0.77) and updated Schwartz (ICC= 0.77) formulas. Schwartz classical formula in patients with GFR24 ≥ 90ml/min/1.73m 2 estimated higher values, while Schwartz updated underestimated values. There is moderate correlation and good concordance between the GFR24 and Schwartz and Schwartz updated formulas. The concordance was better in patients with obesity and lower in women, patients with hyperfiltration and normal weight. Copyright © 2016 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

76 FR 68225 - Corporate Administration Committee Board of Directors Meeting; Sunshine Act

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-03

... NEIGHBORHOOD REINVESTMENT CORPORATION Corporate Administration Committee Board of Directors Meeting; Sunshine Act Time and Date: 1 p.m., Monday, November 14, 2011. Place: 1325 G Street NW., Suite.... Update--Human Resources III. Benefits Activities IV. PeopleSoft Implementation Update V. Strategic...

Digital filtering and model updating methods for improving the robustness of near-infrared multivariate calibrations.

PubMed

Kramer, Kirsten E; Small, Gary W

2009-02-01

Fourier transform near-infrared (NIR) transmission spectra are used for quantitative analysis of glucose for 17 sets of prediction data sampled as much as six months outside the timeframe of the corresponding calibration data. Aqueous samples containing physiological levels of glucose in a matrix of bovine serum albumin and triacetin are used to simulate clinical samples such as blood plasma. Background spectra of a single analyte-free matrix sample acquired during the instrumental warm-up period on the prediction day are used for calibration updating and for determining the optimal frequency response of a preprocessing infinite impulse response time-domain digital filter. By tuning the filter and the calibration model to the specific instrumental response associated with the prediction day, the calibration model is given enhanced ability to operate over time. This methodology is demonstrated in conjunction with partial least squares calibration models built with a spectral range of 4700-4300 cm(-1). By using a subset of the background spectra to evaluate the prediction performance of the updated model, projections can be made regarding the success of subsequent glucose predictions. If a threshold standard error of prediction (SEP) of 1.5 mM is used to establish successful model performance with the glucose samples, the corresponding threshold for the SEP of the background spectra is found to be 1.3 mM. For calibration updating in conjunction with digital filtering, SEP values of all 17 prediction sets collected over 3-178 days displaced from the calibration data are below 1.5 mM. In addition, the diagnostic based on the background spectra correctly assesses the prediction performance in 16 of the 17 cases.

Promethazine overdose

MedlinePlus

Little M. Toxicology emergencies. In: Cameron P, Jelinek G, Kelly A-M, Brown A, Little M, eds. Textbook of Adult Emergency ... US National Library of Medicine; Specialized Information Services; ... Data Network. Promethazine. Updated January 4, 2011. toxnet. ...

75 FR 14589 - Combined Notice of Filings #1

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-26

... Triennial Market Power Update. Filed Date: 03/08/2010. Accession Number: 20100315-0088. Comment Date: 5 p.m....C. Description: PJM Interconnection, LLC submits Wholesale Market Participation Agreement designated... updates to the market based rate application filed 3/12/2010. Filed Date: 03/16/2010. Accession Number...

System for Continuous Delivery of MODIS Imagery to Internet Mapping Applications

NASA Technical Reports Server (NTRS)

Plesea, Lucian

2008-01-01

This software represents a complete, unsupervised processing chain that generates a continuously updating global image of the Earth from the most recent available MODIS Level 1B scenes. The software constantly updates a global image of the Earth at 250 m per pixel.

An Updated Performance Assessment For A New Low-Level Radioactive Waste Disposal Facility In West Texas - 12192

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dornsife, William P.; Kirk, J. Scott; Shaw, Chris G.

2012-07-01

This Performance Assessment (PA) submittal is an update to the original PA that was developed to support the licensing of the Waste Control Specialists LLC Low-Level Radioactive Waste (LLRW) disposal facility. This update includes both the Compact Waste Facility (CWF) and the Federal Waste Facility (FWF), in accordance with Radioactive Material License (RML) No. R04100, License Condition (LC) 87. While many of the baseline assumptions supporting the initial license application PA were incorporated in this update, a new transport code, GoldSim, and new deterministic groundwater flow codes, including HYDRUS and MODFLOWSURFACT{sup TM}, were employed to demonstrate compliance with the performancemore » objectives codified in the regulations and RML No. R04100, LC 87. A revised source term, provided by the Texas Commission on Environmental Quality staff, was used to match the initial 15 year license term. This updated PA clearly confirms and demonstrates the robustness of the characteristics of the site's geology and the advanced engineering design of the disposal units. Based on the simulations from fate and transport models, the radiation doses to members of the general public and site workers predicted in the initial and updated PA were a small fraction of the criterion doses of 0.25 mSv and 50 mSv, respectively. In a comparison between the results of the updated PA against the one developed in support of the initial license, both clearly demonstrated the robustness of the characteristics of the site's geology and engineering design of the disposal units. Based on the simulations from fate and transport models, the radiation doses to members of the general public predicted in the initial and updated PA were a fraction of the allowable 25 mrem/yr (0.25 m sievert/yr) dose standard for tens-of-thousands of years into the future. Draft Texas guidance on performance assessment (TCEQ, 2004) recommends a period of analysis equal to 1,000 years or until peak doses from the more mobile radionuclides occur. The EPA National Emissions Standards for Hazardous Air Pollutants limits radionuclide doses through the air pathway to 10 mrem/yr. Gaseous radionuclide doses from the CWF and the FWF, due to decomposition gases, are a small fraction of the dose limit. The radon flux from the CWF and FWF were compared to the flux limit of 20 pCi/m{sup 2}-s from 40 CFR 192. Because of the thick cover system, the calculated radon flux was a very small fraction of the limit. (authors)« less

Integration of Narrative Processing, Data Fusion, and Database Updating Techniques in an Automated System.

DTIC Science & Technology

1981-10-29

are implemented, respectively, in the files "W-Update," "W-combine" and RW-Copy," listed in the appendix. The appendix begins with a typescript of an...the typescript ) and the copying process (steps 45 and 46) are shown as human actions in the typescript , but can be performed easily by a "master...for Natural Language, M. Marcus, MIT Press, 1980. I 29 APPENDIX: DATABASE UPDATING EXPERIMENT 30 CONTENTS Typescript of an experiment in Rosie

Updates to the Demographic and Spatial Allocation Models to ...

EPA Pesticide Factsheets

EPA's announced the availability of the final report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Version 2). This update furthered land change modeling by providing nationwide housing development scenarios up to 2100. This newest version includes updated population and land use data sets and addresses limitations identified in ICLUS v1 in both the migration and spatial allocation models. The companion user guide (Final Report) describes the development of ICLUS v2 and the updates that were made to the original data sets and the demographic and spatial allocation models. The GIS tool enables users to run SERGoM with the population projections developed for the ICLUS project and allows users to modify the spatial allocation housing density across the landscape.

Landsat-7 ETM+ radiometric calibration status

USGS Publications Warehouse

Barsi, Julia A.; Markham, Brian L.; Czapla-Myers, J. S.; Helder, Dennis L.; Hook, Simon; Schott, John R.; Haque, Md. Obaidul

2016-01-01

Now in its 17th year of operation, the Enhanced Thematic Mapper + (ETM+), on board the Landsat-7 satellite, continues to systematically acquire imagery of the Earth to add to the 40+ year archive of Landsat data. Characterization of the ETM+ on-orbit radiometric performance has been on-going since its launch in 1999. The radiometric calibration of the reflective bands is still monitored using on-board calibration devices, though the Pseudo-Invariant Calibration Sites (PICS) method has proven to be an effective tool as well. The calibration gains were updated in April 2013 based primarily on PICS results, which corrected for a change of as much as -0.2%/year degradation in the worst case bands. A new comparison with the SADE database of PICS results indicates no additional degradation in the updated calibration. PICS data are still being tracked though the recent trends are not well understood. The thermal band calibration was updated last in October 2013 based on a continued calibration effort by NASA/Jet Propulsion Lab and Rochester Institute of Technology. The update accounted for a 0.036 W/m2 sr μm or 0.26K at 300K bias error. The updated lifetime trend is now stable to within +/- 0.4K.

A Routing Protocol for Packet Radio Networks

DTIC Science & Technology

1995-01-01

table of node K is a matrix containing, for each destination L and each neighbor of K (say M ), the distance to L ( NEOPRQ ) and the predecessor ( S OP Q...identifier T The distance to the destination ( N OP ) T The predecessor of the shortest path chosen toward L ( S OP ) T The successor ( U OP ) of the shortest...P and the predecessor is updated as S OP À ¾ S Q P . Thus, a node can determine whether or not an update received from M affects its other distance

Establishing an In-House Wind Maintenance Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2011-12-01

Update to the 2008 guidebook titled “Establishing an In-house Wind Maintenance Program”, which was developed to support utilities in developing O&M strategies. This update includes significant contributions from utilities and other stakeholders around the country, representing all perspectives and regardless of whether or not they own wind turbines or projects.

Assessment Update: Progress, Trends, and Practices in Higher Education. Volume 26, Issue 1, January-February 2014

ERIC Educational Resources Information Center

Banta, Trudy W., Ed.

2014-01-01

This issue of "Assessment Update" presents the following articles: (1) Expanding Assessment Perspectives: The Importance of Student Leadership in Student Learning Outcomes Assessment (Abraham J. Lauer and Jamie R. Korin); (2) Empowering Faculty and Students with Assessment Data (Jane M. Souza); (3) Including Faculty in Accreditation…

Assessment Update: Progress, Trends, and Practices in Higher Education. Volume 25, Issue 2, March-April 2013

ERIC Educational Resources Information Center

Banta, Trudy W., Ed.

2013-01-01

This issue of "Assessment Update" presents the following articles: (1) "Just Right" Outcomes Assessment: A Fable for Higher Education (Catherine M. Wehlburg); (2) Editor's Notes: Helping Faculty Members Learn (Linda Suskie); (3) Focus on the Bottom-Line: Assessing Business Writing (Michael Cherry and George Klemic); (4)…

Perception of 3-D location based on vision, touch, and extended touch

PubMed Central

Giudice, Nicholas A.; Klatzky, Roberta L.; Bennett, Christopher R.; Loomis, Jack M.

2012-01-01

Perception of the near environment gives rise to spatial images in working memory that continue to represent the spatial layout even after cessation of sensory input. As the observer moves, these spatial images are continuously updated.This research is concerned with (1) whether spatial images of targets are formed when they are sensed using extended touch (i.e., using a probe to extend the reach of the arm) and (2) the accuracy with which such targets are perceived. In Experiment 1, participants perceived the 3-D locations of individual targets from a fixed origin and were then tested with an updating task involving blindfolded walking followed by placement of the hand at the remembered target location. Twenty-four target locations, representing all combinations of two distances, two heights, and six azimuths, were perceived by vision or by blindfolded exploration with the bare hand, a 1-m probe, or a 2-m probe. Systematic errors in azimuth were observed for all targets, reflecting errors in representing the target locations and updating. Overall, updating after visual perception was best, but the quantitative differences between conditions were small. Experiment 2 demonstrated that auditory information signifying contact with the target was not a factor. Overall, the results indicate that 3-D spatial images can be formed of targets sensed by extended touch and that perception by extended touch, even out to 1.75 m, is surprisingly accurate. PMID:23070234

Cross-Talk in Comp Theory: A Reader. Second Edition, Revised and Updated.

ERIC Educational Resources Information Center

Villanueva, Victor, Ed.

This revised and updated resource contains a total of 43 essays that serve to initiate graduate students and more experienced teachers into the theories that inform composition studies. Under Section One--The Givens in Our Conversations: The Writing Process--are these essays: "Teach Writing as a Process Not Product" (Donald M. Murray);…

Updating Sensory "versus" Task Representations during Task-Switching: Insights from Cognitive Brain Potentials in Humans

ERIC Educational Resources Information Center

Perianez, Jose A.; Barcelo, Francisco

2009-01-01

Task-cueing studies suggest that the updating of sensory and task representations both contribute to behavioral task-switch costs [Forstmann, B. U., Brass, M., & Koch, I. (2007). "Methodological and empirical issues when dissociating cue-related from task-related processes in the explicit task-cuing procedure." "Psychological Research, 71"(4),…

Assessment Update: Progress, Trends, and Practices in Higher Education. Volume 24, Issue 3, May-June 2012

ERIC Educational Resources Information Center

Banta, Trudy W., Ed.

2012-01-01

This issue of "Assessment Update" presents the following articles: (1) A "Wisdom of Crowds" Approach to Outcomes Assessment (Gregory Burton); (2) Editor's Notes: Collective Assessment and DQP Follow-Up (Trudy W. Banta); (3) Satisfaction with Data Management Systems in Standards-Based Alignment (Brett Everhart and Jeanne M.…

Assessment Update: Progress, Trends, and Practices in Higher Education. Volume 29, Issue 6, November-December 2017

ERIC Educational Resources Information Center

Hundley, Stephen P., Ed.

2017-01-01

This issue of "Assessment Update" presents the following articles: (1) Lessons Learned: Graduate Student Assessment (Michael Cherry and Lesley Page); (2) Assessing the Assessor: A Response to Fulcher and Bashkov's "Do We Practice What We Preach? The Accountability of an Assessment Office" (Christine Robinson, John G. M.…

SPITZER 70 AND 160 {mu}m OBSERVATIONS OF THE COSMOS FIELD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frayer, D. T.; Huynh, M. T.; Bhattacharya, B.

2009-11-15

We present Spitzer 70 and 160 {mu}m observations of the COSMOS Spitzer survey (S-COSMOS). The data processing techniques are discussed for the publicly released products consisting of images and source catalogs. We present accurate 70 and 160 {mu}m source counts of the COSMOS field and find reasonable agreement with measurements in other fields and with model predictions. The previously reported counts for GOODS-North and the extragalactic First Look Survey are updated with the latest calibration, and counts are measured based on the large area SWIRE survey to constrain the bright source counts. We measure an extragalactic confusion noise level ofmore » {sigma} {sub c} = 9.4 {+-} 3.3 mJy (q = 5) for the MIPS 160 {mu}m band based on the deep S-COSMOS data and report an updated confusion noise level of {sigma} {sub c} = 0.35 {+-} 0.15 mJy (q = 5) for the MIPS 70 {mu}m band.« less

Erratum: Measurement of σ(e+e-→ψ(3770)→hadrons) at Ec.m.=3773MeV [Phys. Rev. Lett. 96, 092002 (2006)

NASA Astrophysics Data System (ADS)

Besson, D.; Pedlar, T. K.; Cronin-Hennessy, D.; Gao, K. Y.; Gong, D. T.; Hietala, J.; Kubota, Y.; Klein, T.; Lang, B. W.; Poling, R.; Scott, A. W.; Smith, A.; Dobbs, S.; Metreveli, Z.; Seth, K. K.; Tomaradze, A.; Zweber, P.; Ernst, J.; Arms, K.; Severini, H.; Dytman, S. A.; Love, W.; Mehrabyan, S.; Mueller, J. A.; Savinov, V.; Li, Z.; Lopez, A.; Mendez, H.; Ramirez, J.; Huang, G. S.; Miller, D. H.; Pavlunin, V.; Sanghi, B.; Shipsey, I. P. J.; Adams, G. S.; Anderson, M.; Cummings, J. P.; Danko, I.; Napolitano, J.; He, Q.; Muramatsu, H.; Park, C. S.; Thorndike, E. H.; Coan, T. E.; Gao, Y. S.; Liu, F.; Artuso, M.; Boulahouache, C.; Blusk, S.; Butt, J.; Li, J.; Menaa, N.; Mountain, R.; Nisar, S.; Randrianarivony, K.; Redjimi, R.; Sia, R.; Skwarnicki, T.; Stone, S.; Wang, J. C.; Zhang, K.; Csorna, S. E.; Bonvicini, G.; Cinabro, D.; Dubrovin, M.; Lincoln, A.; Briere, R. A.; Chen, G. P.; Chen, J.; Ferguson, T.; Tatishvili, G.; Vogel, H.; Watkins, M. E.; Rosner, J. L.; Adam, N. E.; Alexander, J. P.; Berkelman, K.; Cassel, D. G.; Duboscq, J. E.; Ecklund, K. M.; Ehrlich, R.; Fields, L.; Gibbons, L.; Gray, R.; Gray, S. W.; Hartill, D. L.; Heltsley, B. K.; Hertz, D.; Jones, C. D.; Kandaswamy, J.; Kreinick, D. L.; Kuznetsov, V. E.; Mahlke-Krüger, H.; Meyer, T. O.; Onyisi, P. U. E.; Patterson, J. R.; Peterson, D.; Phillips, E. A.; Pivarski, J.; Riley, D.; Ryd, A.; Sadoff, A. J.; Schwarthoff, H.; Shi, X.; Stroiney, S.; Sun, W. M.; Wilksen, T.; Weinberger, M.; Athar, S. B.; Avery, P.; Breva-Newell, L.; Patel, R.; Potlia, V.; Stoeck, H.; Yelton, J.; Rubin, P.; Cawlfield, C.; Eisenstein, B. I.; Karliner, I.; Kim, D.; Lowrey, N.; Naik, P.; Sedlack, C.; Selen, M.; White, E. J.; Wiss, J.; Shepherd, M. R.; Asner, D. M.; Edwards, K. W.

2010-04-01

We have updated our measurement of the cross section for e^+e^- -> psi(3770) -> hadrons, our publication "Measurement of sigma(e^+e^- -> psi(3770) -> hadrons) at E_{c.m.} = 3773 MeV", arXiv:hep-ex/0512038, Phys.Rev.Lett.96, 092002 (2006). Simultaneous with this arXiv update, we have published an erratum in Phys.Rev.Lett.104, 159901 (2010). There, and in this update, we have corrected a mistake in the computation of the error on the difference of the cross sections for e^+e^- -> psi(3770) -> hadrons and e^+e^- -> psi(3770) -> DDbar. We have also used a more recent CLEO measurement of cross section for e^+e^- -> psi(3770) -> DDbar. From this, we obtain an upper limit on the branching fraction for psi(3770) -> non-DDbar of 9% at 90% confidence level.

Updating of Aversive Memories after Temporal Error Detection Is Differentially Modulated by mTOR across Development

ERIC Educational Resources Information Center

Tallot, Lucille; Diaz-Mataix, Lorenzo; Perry, Rosemarie E.; Wood, Kira; LeDoux, Joseph E.; Mouly, Anne-Marie; Sullivan, Regina M.; Doyère, Valérie

2017-01-01

The updating of a memory is triggered whenever it is reactivated and a mismatch from what is expected (i.e., prediction error) is detected, a process that can be unraveled through the memory's sensitivity to protein synthesis inhibitors (i.e., reconsolidation). As noted in previous studies, in Pavlovian threat/aversive conditioning in adult rats,…

Updating of aversive memories after temporal error detection is differentially modulated by mTOR across development

PubMed Central

Tallot, Lucille; Diaz-Mataix, Lorenzo; Perry, Rosemarie E.; Wood, Kira; LeDoux, Joseph E.; Mouly, Anne-Marie; Sullivan, Regina M.; Doyère, Valérie

2017-01-01

The updating of a memory is triggered whenever it is reactivated and a mismatch from what is expected (i.e., prediction error) is detected, a process that can be unraveled through the memory's sensitivity to protein synthesis inhibitors (i.e., reconsolidation). As noted in previous studies, in Pavlovian threat/aversive conditioning in adult rats, prediction error detection and its associated protein synthesis-dependent reconsolidation can be triggered by reactivating the memory with the conditioned stimulus (CS), but without the unconditioned stimulus (US), or by presenting a CS–US pairing with a different CS–US interval than during the initial learning. Whether similar mechanisms underlie memory updating in the young is not known. Using similar paradigms with rapamycin (an mTORC1 inhibitor), we show that preweaning rats (PN18–20) do form a long-term memory of the CS–US interval, and detect a 10-sec versus 30-sec temporal prediction error. However, the resulting updating/reconsolidation processes become adult-like after adolescence (PN30–40). Our results thus show that while temporal prediction error detection exists in preweaning rats, specific infant-type mechanisms are at play for associative learning and memory. PMID:28202715

Who's Who? Memory updating and character reference in children's narratives.

PubMed

Whitely, Cristy; Colozzo, Paola

2013-10-01

The capacity to update and monitor the contents of working memory is an executive function presumed to play a critical role in language processing. The current study used an individual differences approach to consider the relationship between memory updating and accurate reference to story characters in the narratives of typically developing children. English-speaking children from kindergarten to grade 2 ( N = 63; M age = 7.0 years) completed updating tasks, short-term memory tasks, and narrative productions. The authors used multiple regression to test whether updating accounted for independent variability in referential adequacy. The capacity to update working memory was related to adequate character reference beyond the effects of age and of short-term memory capacity, with the strongest relationship emerging for maintaining reference over multiple utterances. This individual differences study is the first to show a link between updating and performance in a discourse production task for young school-age children. The findings contribute to the growing body of research investigating the role of working memory in shaping language production. This study invites extension to children of different ages and language abilities as well as to other language production tasks.

A Quantitative Analysis of the Soviet Economy. Volume 1. Expansion of the 1972 Soviet Input-Output Tables

DTIC Science & Technology

1982-12-15

Headquarters Defense Nuclear Agency Washington, D.C. 20305 91 1011 079 Suite 1000. 1901 North Moore Street. Arlington, Virginia 22209 (703) 243-2 0-7 7...1972 Soviet InQut-,Outut Tables I G. E. Pugh M. T. Nunenkamp IJ.C. Krupp prepared under Contract No, DNA001-79-C-0444 for: 1:eadquar- ers Defense Nuclear ...4-1 4.2 Extent and Scope of the Update 4-2 4.3 The Updating Methodology 4-3 4.4 Results of the Updating Process 4-10 REFERENCES R-1 APPENDICES A

77 FR 778 - Council Coordination Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-06

... meeting of the Council Coordination Committee (CCC), consisting of the Regional Fishery Management Council... this meeting and provide reports to the CCC for its information and discussion. All sessions are open...:45 p.m.--Other Business, updates, and next annual CCC Meeting. 4:45 p.m.-5:30 p.m.--Wrap-up. 5:30 p.m...

THE CALIFORNIA PLANET SURVEY IV: A PLANET ORBITING THE GIANT STAR HD 145934 AND UPDATES TO SEVEN SYSTEMS WITH LONG-PERIOD PLANETS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Katherina Feng, Y.; Wright, Jason T.; Nelson, Benjamin

2015-02-10

We present an update to seven stars with long-period planets or planetary candidates using new and archival radial velocities from Keck-HIRES and literature velocities from other telescopes. Our updated analysis better constrains orbital parameters for these planets, four of which are known multi-planet systems. HD 24040 b and HD 183263 c are super-Jupiters with circular orbits and periods longer than 8 yr. We present a previously unseen linear trend in the residuals of HD 66428 indicative of an additional planetary companion. We confirm that GJ 849 is a multi-planet system and find a good orbital solution for the c component: it is a 1more » M {sub Jup} planet in a 15 yr orbit (the longest known for a planet orbiting an M dwarf). We update the HD 74156 double-planet system. We also announce the detection of HD 145934 b, a 2 M {sub Jup} planet in a 7.5 yr orbit around a giant star. Two of our stars, HD 187123 and HD 217107, at present host the only known examples of systems comprising a hot Jupiter and a planet with a well constrained period greater than 5 yr, and with no evidence of giant planets in between. Our enlargement and improvement of long-period planet parameters will aid future analysis of origins, diversity, and evolution of planetary systems.« less

The reciprocal relationship between executive function and theory of mind in middle childhood: a 1-year longitudinal perspective.

PubMed

Austin, Gina; Groppe, Karoline; Elsner, Birgit

2014-01-01

There is robust evidence showing a link between executive function (EF) and theory of mind (ToM) in 3- to 5-year-olds. However, it is unclear whether this relationship extends to middle childhood. In addition, there has been much discussion about the nature of this relationship. Whereas some authors claim that ToM is needed for EF, others argue that ToM requires EF. To date, however, studies examining the longitudinal relationship between distinct subcomponents of EF [i.e., attention shifting, working memory (WM) updating, inhibition] and ToM in middle childhood are rare. The present study examined (1) the relationship between three EF subcomponents (attention shifting, WM updating, inhibition) and ToM in middle childhood, and (2) the longitudinal reciprocal relationships between the EF subcomponents and ToM across a 1-year period. EF and ToM measures were assessed experimentally in a sample of 1,657 children (aged 6-11 years) at time point one (t1) and 1 year later at time point two (t2). Results showed that the concurrent relationships between all three EF subcomponents and ToM pertained in middle childhood at t1 and t2, respectively, even when age, gender, and fluid intelligence were partialled out. Moreover, cross-lagged structural equation modeling (again, controlling for age, gender, and fluid intelligence, as well as for the earlier levels of the target variables), revealed partial support for the view that early ToM predicts later EF, but stronger evidence for the assumption that early EF predicts later ToM. The latter was found for attention shifting and WM updating, but not for inhibition. This reveals the importance of studying the exact interplay of ToM and EF across childhood development, especially with regard to different EF subcomponents. Most likely, understanding others' mental states at different levels of perspective-taking requires specific EF subcomponents, suggesting developmental change in the relations between EF and ToM across childhood.

Egocentric-updating during navigation facilitates episodic memory retrieval.

PubMed

Gomez, Alice; Rousset, Stéphane; Baciu, Monica

2009-11-01

Influential models suggest that spatial processing is essential for episodic memory [O'Keefe, J., & Nadel, L. (1978). The hippocampus as a cognitive map. London: Oxford University Press]. However, although several types of spatial relations exist, such as allocentric (i.e. object-to-object relations), egocentric (i.e. static object-to-self relations) or egocentric updated on navigation information (i.e. self-to-environment relations in a dynamic way), usually only allocentric representations are described as potentially subserving episodic memory [Nadel, L., & Moscovitch, M. (1998). Hippocampal contributions to cortical plasticity. Neuropharmacology, 37(4-5), 431-439]. This study proposes to confront the allocentric representation hypothesis with an egocentric updated with self-motion representation hypothesis. In the present study, we explored retrieval performance in relation to these two types of spatial processing levels during learning. Episodic remembering has been assessed through Remember responses in a recall and in a recognition task, combined with a "Remember-Know-Guess" paradigm [Gardiner, J. M. (2001). Episodic memory and autonoetic consciousness: A first-person approach. Philosophical Transactions of the Royal Society B: Biological Sciences, 356(1413), 1351-1361] to assess the autonoetic level of responses. Our results show that retrieval performance was significantly higher when encoding was performed in the egocentric-updated condition. Although egocentric updated with self-motion and allocentric representations are not mutually exclusive, these results suggest that egocentric updating processing facilitates remember responses more than allocentric processing. The results are discussed according to Burgess and colleagues' model of episodic memory [Burgess, N., Becker, S., King, J. A., & O'Keefe, J. (2001). Memory for events and their spatial context: models and experiments. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 356(1413), 1493-1503].

2014 Update of the Pacific Northwest portion of the U.S. National Seismic Hazard Maps

USGS Publications Warehouse

Frankel, Arthur; Chen, Rui; Petersen, Mark; Moschetti, Morgan P.; Sherrod, Brian

2015-01-01

Several aspects of the earthquake characterization were changed for the Pacific Northwest portion of the 2014 update of the national seismic hazard maps, reflecting recent scientific findings. New logic trees were developed for the recurrence parameters of M8-9 earthquakes on the Cascadia subduction zone (CSZ) and for the eastern edge of their rupture zones. These logic trees reflect recent findings of additional M8 CSZ earthquakes using offshore deposits of turbidity flows and onshore tsunami deposits and subsidence. These M8 earthquakes each rupture a portion of the CSZ and occur in the time periods between M9 earthquakes that have an average recurrence interval of about 500 years. The maximum magnitude was increased for deep intraslab earthquakes. An areal source zone to account for the possibility of deep earthquakes under western Oregon was expanded. The western portion of the Tacoma fault was added to the hazard maps.

An integrated approach for updating cadastral maps in Pakistan using satellite remote sensing data

NASA Astrophysics Data System (ADS)

Ali, Zahir; Tuladhar, Arbind; Zevenbergen, Jaap

2012-08-01

Updating cadastral information is crucial for recording land ownership and property division changes in a timely fashioned manner. In most cases, the existing cadastral maps do not provide up-to-date information on land parcel boundaries. Such a situation demands that all the cadastral data and parcel boundaries information in these maps to be updated in a timely fashion. The existing techniques for acquiring cadastral information are discipline-oriented based on different disciplines such as geodesy, surveying, and photogrammetry. All these techniques require a large number of manpower, time, and cost when they are carried out separately. There is a need to integrate these techniques for acquiring cadastral information to update the existing cadastral data and (re)produce cadastral maps in an efficient manner. To reduce the time and cost involved in cadastral data acquisition, this study develops an integrated approach by integrating global position system (GPS) data, remote sensing (RS) imagery, and existing cadastral maps. For this purpose, the panchromatic image with 0.6 m spatial resolution and the corresponding multi-spectral image with 2.4 m spatial resolution and 3 spectral bands from QuickBird satellite were used. A digital elevation model (DEM) was extracted from SPOT-5 stereopairs and some ground control points (GCPs) were also used for ortho-rectifying the QuickBird images. After ortho-rectifying these images and registering the multi-spectral image to the panchromatic image, fusion between them was attained to get good quality multi-spectral images of these two study areas with 0.6 m spatial resolution. Cadastral parcel boundaries were then identified on QuickBird images of the two study areas via visual interpretation using participatory-GIS (PGIS) technique. The regions of study are the urban and rural areas of Peshawar and Swabi districts in the Khyber Pakhtunkhwa province of Pakistan. The results are the creation of updated cadastral maps with a lot of cadastral information which can be used in updating the existing cadastral data with less time and cost.

Addendum to "Charm and bottom quark masses: An update"

NASA Astrophysics Data System (ADS)

Chetyrkin, Konstantin G.; Kühn, Johann H.; Maier, Andreas; Maierhöfer, Philipp; Marquard, Peter; Steinhauser, Matthias; Sturm, Christian

2017-12-01

We update the experimental moments for the charm quark as computed in [J. H. Kühn, M. Steinhauser, and C. Sturm, Nucl. Phys. B778, 192 (2007), 10.1016/j.nuclphysb.2007.04.036] and used in [K. G. Chetyrkin, J. H. Kühn, A. Maier, P. Maierhöfer, P. Marquard, M. Steinhauser, and C. Sturm, Phys. Rev. D 80, 074010 (2009),, 10.1103/PhysRevD.80.074010 K. Chetyrkin, J. H. Kühn, A. Maier, P. Maierhöfer, P. Marquard, M. Steinhauser, and C. Sturm, Theor. Math. Phys. 170, 217 (2012), 10.1007/s11232-012-0024-7] for the determination of the charm-quark mass. The new value for the MS ¯ charm-quark mass reads mc(3 GeV )=0.993 ±0.008 GeV .

76 FR 7881 - Advisory Committee for Environmental Research and Education; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

.... March 17 Update on NSF's Science, Engineering and Education for Sustainability portfolio (SEES). Dated... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... and Education, 9487. Dates: March 16, 2011, 8:30 a.m.-5 p.m. and March 17, 2011, 8:30 a.m.-2 p.m...

77 FR 6826 - Advisory Committee for Environmental Research and Education; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-09

... Thursday, March 15, 2012 Update on NSF's Science, Engineering and Education for Sustainability portfolio... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... and Education (9487). Dates: March 14, 2012, 8:30 a.m.- 5 p.m.; March 15, 2012, 8:30 a.m.-2 p.m. Place...

Updates to the Demographic and Spatial Allocation Models to ...

EPA Pesticide Factsheets

EPA announced the availability of the draft report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) for a 30-day public comment period. The ICLUS version 2 (v2) modeling tool furthered land change modeling by providing nationwide housing development scenarios up to 2100. ICLUS V2 includes updated population and land use data sets and addressing limitations identified in ICLUS v1 in both the migration and spatial allocation models. The companion user guide describes the development of ICLUS v2 and the updates that were made to the original data sets and the demographic and spatial allocation models. [2017 UPDATE] Get the latest version of ICLUS and stay up-to-date by signing up to the ICLUS mailing list. The GIS tool enables users to run SERGoM with the population projections developed for the ICLUS project and allows users to modify the spatial allocation housing density across the landscape.

5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex.

PubMed

Morici, Juan Facundo; Miranda, Magdalena; Gallo, Francisco Tomás; Zanoni, Belén; Bekinschtein, Pedro; Weisstaub, Noelia V

2018-05-02

Context-dependent memories may guide adaptive behavior relaying in previous experience while updating stored information through reconsolidation. Retrieval can be triggered by partial and shared cues. When the cue is presented, the most relevant memory should be updated. In a contextual version of the object recognition task, we examined the effect of medial PFC (mPFC) serotonin 2a receptor (5-HT2aR) blockade during retrieval in reconsolidation of competing objects memories. We found that mPFC 5-HT2aR controls retrieval and reconsolidation of object memories in the perirhinal cortex (PRH), but not in the dorsal hippocampus in rats. Also, reconsolidation of objects memories in PRH required a functional interaction between the ventral hippocampus and the mPFC. Our results indicate that in the presence of conflicting information at retrieval, mPFC 5-HT2aR may facilitate top-down context-guided control over PRH to control the behavioral response and object memory reconsolidation. © 2018, Morici et al.

5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex

PubMed Central

Morici, Juan Facundo; Miranda, Magdalena; Gallo, Francisco Tomás; Zanoni, Belén; Bekinschtein, Pedro

2018-01-01

Context-dependent memories may guide adaptive behavior relaying in previous experience while updating stored information through reconsolidation. Retrieval can be triggered by partial and shared cues. When the cue is presented, the most relevant memory should be updated. In a contextual version of the object recognition task, we examined the effect of medial PFC (mPFC) serotonin 2a receptor (5-HT2aR) blockade during retrieval in reconsolidation of competing objects memories. We found that mPFC 5-HT2aR controls retrieval and reconsolidation of object memories in the perirhinal cortex (PRH), but not in the dorsal hippocampus in rats. Also, reconsolidation of objects memories in PRH required a functional interaction between the ventral hippocampus and the mPFC. Our results indicate that in the presence of conflicting information at retrieval, mPFC 5-HT2aR may facilitate top-down context-guided control over PRH to control the behavioral response and object memory reconsolidation. PMID:29717980

M2e-Based Universal Influenza A Vaccines

PubMed Central

Deng, Lei; Cho, Ki Joon; Fiers, Walter; Saelens, Xavier

2015-01-01

The successful isolation of a human influenza virus in 1933 was soon followed by the first attempts to develop an influenza vaccine. Nowadays, vaccination is still the most effective method to prevent human influenza disease. However, licensed influenza vaccines offer protection against antigenically matching viruses, and the composition of these vaccines needs to be updated nearly every year. Vaccines that target conserved epitopes of influenza viruses would in principle not require such updating and would probably have a considerable positive impact on global human health in case of a pandemic outbreak. The extracellular domain of Matrix 2 (M2e) protein is an evolutionarily conserved region in influenza A viruses and a promising epitope for designing a universal influenza vaccine. Here we review the seminal and recent studies that focused on M2e as a vaccine antigen. We address the mechanism of action and the clinical development of M2e-vaccines. Finally, we try to foresee how M2e-based vaccines could be implemented clinically in the future. PMID:26344949

76 FR 7231 - Wild Horse and Burro Advisory Board; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-09

... Sheraton Phoenix Downtown Hotel, 340 N. 3rd Street, Phoenix, Arizona, 85004. The hotel phone number for... June 15, 2010 Minutes Program Updates Gathers Adoptions Budget Facilities Break (2:20 p.m.--2:45 p.m...

75 FR 61779 - National Science Board: Sunshine Act Meetings; Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-06

...:30 p.m. to 3 p.m. SUBJECT MATTER: Review of NSB Action Item (NSB/CPP-10-63) (Deep Underground Science... National Science Board Web site http://www.nsf.gov/nsb for additional information and schedule updates...

Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics: the PREVENCION study.

PubMed

Medina-Lezama, Josefina; Pastorius, Catherine A; Zea-Diaz, Humberto; Bernabe-Ortiz, Antonio; Corrales-Medina, Fernando; Morey-Vargas, Oscar Leopoldo; Chirinos, Diana Andrea; Muñoz-Atahualpa, Edgar; Chirinos-Pacheco, Julio; Chirinos, Julio Alonso

2010-06-01

We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults. Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD). Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 cm in men and women, respectively. With these cutoffs, there was substantial disagreement between the original American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) and the recently updated MetS definition, particularly among men (kappa = 0.85). Subjects with MetS identified by the updated definition but not meeting the original AHA/NHLBI MetS criteria demonstrated significantly increased cIMT (P < 0.001) compared with subjects who did not meet the MetS criteria by either definition. Our findings support the use of ethnic-specific waist circumference cutoffs and the updated MetS definition in Andean adults.

Impact of one's own mobile phone in stand-by mode on personal radiofrequency electromagnetic field exposure.

PubMed

Urbinello, Damiano; Röösli, Martin

2013-01-01

When moving around, mobile phones in stand-by mode periodically send data about their positions. The aim of this paper is to evaluate how personal radiofrequency electromagnetic field (RF-EMF) measurements are affected by such location updates. Exposure from a mobile phone handset (uplink) was measured during commuting by using a randomized cross-over study with three different scenarios: disabled mobile phone (reference), an activated dual-band phone and a quad-band phone. In the reference scenario, uplink exposure was highest during train rides (1.19 mW/m(2)) and lowest during car rides in rural areas (0.001 mW/m(2)). In public transports, the impact of one's own mobile phone on personal RF-EMF measurements was not observable because of high background uplink radiation from other people's mobile phone. In a car, uplink exposure with an activated phone was orders of magnitude higher compared with the reference scenario. This study demonstrates that personal RF-EMF exposure is affected by one's own mobile phone in stand-by mode because of its regular location update. Further dosimetric studies should quantify the contribution of location updates to the total RF-EMF exposure in order to clarify whether the duration of mobile phone use, the most common exposure surrogate in the epidemiological RF-EMF research, is actually an adequate exposure proxy.

Prophylaxis and treatment of HIV-1 infection in pregnancy - Swedish Recommendations 2017.

PubMed

Navér, Lars; Albert, Jan; Carlander, Christina; Flamholc, Leo; Gisslén, Magnus; Karlström, Olof; Svedhem-Johansson, Veronica; Sönnerborg, Anders; Westling, Katarina; Yilmaz, Aylin; Pettersson, Karin

2018-01-24

Prophylaxis and treatment with antiretroviral drugs have resulted in a very low rate of mother-to-child transmission (MTCT) of HIV during recent years. Registration of new antiretroviral drugs, modification of clinical praxis, updated general treatment guidelines and increasing knowledge about MTCT have necessitated regular revisions of the recommendations for 'Prophylaxis and treatment of HIV-1 infection in pregnancy'. The Swedish Reference Group for Antiviral Therapy (RAV) has updated the recommendations from 2013 at an expert meeting 19 September 2017. In the new text, current treatment guidelines for non-pregnant are considered. The most important revisions are that: (1) Caesarean section and infant prophylaxis with three drugs are recommended when maternal HIV RNA >150 copies/mL (previously >50 copies/mL). The treatment target of undetectable HIV RNA remains unchanged <50 copies/mL; (2) Obstetric management and mode of delivery at premature rupture of the membranes and rupture of the membranes at full term follow the same procedures as in HIV negative women; (3) Vaginal delivery is recommended to a well-treated woman with HIV RNA <150 copies/mL regardless of gestational age, if no obstetric contraindications are present; (4) Treatment during pregnancy should begin as soon as possible and should continue after delivery; (5) Ongoing well-functioning HIV treatment at pregnancy start should usually be retained; (6) Recommended drugs and drug combinations have been updated.

INDEPENDENT EVALUATION OF THE GAM EX5ALN MINIATURE LINE-NARROWED KRF EXCIMER LASER

DTIC Science & Technology

2017-06-01

software included the disabled tabs and buttons that clutter the panels. Information on these panels was not updated correctly (e.g., shots per fill and...total shots are not stored correctly and appear to contain random data, the lock function on the fill page does not update correctly, the time to...fill level after 7 M shots . .............................................................................. Error! Bookmark not defined. 7: Shelf-life

Thermodynamic characterization of tandem mismatches found in naturally occurring RNA

PubMed Central

Christiansen, Martha E.; Znosko, Brent M.

2009-01-01

Although all sequence symmetric tandem mismatches and some sequence asymmetric tandem mismatches have been thermodynamically characterized and a model has been proposed to predict the stability of previously unmeasured sequence asymmetric tandem mismatches [Christiansen,M.E. and Znosko,B.M. (2008) Biochemistry, 47, 4329–4336], experimental thermodynamic data for frequently occurring tandem mismatches is lacking. Since experimental data is preferred over a predictive model, the thermodynamic parameters for 25 frequently occurring tandem mismatches were determined. These new experimental values, on average, are 1.0 kcal/mol different from the values predicted for these mismatches using the previous model. The data for the sequence asymmetric tandem mismatches reported here were then combined with the data for 72 sequence asymmetric tandem mismatches that were published previously, and the parameters used to predict the thermodynamics of previously unmeasured sequence asymmetric tandem mismatches were updated. The average absolute difference between the measured values and the values predicted using these updated parameters is 0.5 kcal/mol. This updated model improves the prediction for tandem mismatches that were predicted rather poorly by the previous model. This new experimental data and updated predictive model allow for more accurate calculations of the free energy of RNA duplexes containing tandem mismatches, and, furthermore, should allow for improved prediction of secondary structure from sequence. PMID:19509311

SOP conservative (medical and mechanical) treatment of erectile dysfunction.

PubMed

Porst, Hartmut; Burnett, Arthur; Brock, Gerald; Ghanem, Hussein; Giuliano, Francois; Glina, Sidney; Hellstrom, Wayne; Martin-Morales, Antonio; Salonia, Andrea; Sharlip, Ira

2013-01-01

Erectile dysfunction (ED) is the most frequently treated male sexual dysfunction worldwide. ED is a chronic condition that exerts a negative impact on male self-esteem and nearly all life domains including interpersonal, family, and business relationships. The aim of this study is to provide an updated overview on currently used and available conservative treatment options for ED with a special focus on their efficacy, tolerability, safety, merits, and limitations including the role of combination therapies for monotherapy failures. The methods used were PubMed and MEDLINE searches using the following keywords: ED, phosphodiesterase type 5 (PDE5) inhibitors, oral drug therapy, intracavernosal injection therapy, transurethral therapy, topical therapy, and vacuum-erection therapy/constriction devices. Additionally, expert opinions by the authors of this article are included. Level 1 evidence exists that changes in sedentary lifestyle with weight loss and optimal treatment of concomitant diseases/risk factors (e.g., diabetes, hypertension, and dyslipidemia) can either improve ED or add to the efficacy of ED-specific therapies, e.g., PDE5 inhibitors. Level 1 evidence also exists that treatment of hypogonadism with total testosterone < 300 ng/dL (10.4 nmol/L) can either improve ED or add to the efficacy of PDE5 inhibitors. There is level 1 evidence regarding the efficacy and safety of the following monotherapies in a spectrum-wide range of ED populations: PDE5 inhibitors, intracavernosal injection therapy with prostaglandin E1 (PGE1, synonymous alprostadil) or vasoactive intestinal peptide (VIP)/phentolamine, and transurethral PGE1 therapy. There is level 2 evidence regarding the efficacy and safety of the following ED treatments: vacuum-erection therapy in a wide range of ED populations, oral L-arginine (3-5 g), topical PGE1 in special ED populations, intracavernosal injection therapy with papaverine/phentolamine (bimix), or papaverine/phentolamine/PGE1 (trimix) combination mixtures. There is level 3 evidence regarding the efficacy and safety of oral yohimbine in nonorganic ED. There is level 3 evidence that combination therapies of PDE5 inhibitors + either transurethral or intracavernosal injection therapy generate better efficacy rates than either monotherapy alone. There is level 4 evidence showing enhanced efficacy with the combination of vacuum-erection therapy + either PDE5 inhibitor or transurethral PGE1 or intracavernosal injection therapy. There is level 5 evidence (expert opinion) that combination therapy of PDE5 inhibitors + L-arginine or daily dosing of tadalafil + short-acting PDE5 inhibitors pro re nata may rescue PDE5 inhibitor monotherapy failures. There is level 5 evidence (expert opinion) that adding either PDE5 inhibitors or transurethral PGE1 may improve outcome of penile prosthetic surgery regarding soft (cold) glans syndrome. There is level 5 evidence (expert opinion) that the combination of PDE5 inhibitors and dapoxetine is effective and safe in patients suffering from both ED and premature ejaculation. © 2013 International Society for Sexual Medicine.

KSC 50-MHz Doppler Radar Wind Profiler (DRWP) Operational Acceptance Test (OAT) Report

NASA Technical Reports Server (NTRS)

Barbre, Robert E.

2015-01-01

This report documents analysis results of the Kennedy Space Center updated 50-MHz Doppler Radar Wind Profiler (DRWP) Operational Acceptance Test (OAT). This test was designed to demonstrate that the new DRWP operates in a similar manner to the previous DRWP for use as a situational awareness asset for mission operations at the Eastern Range to identify rapid changes in the wind environment that weather balloons cannot depict. Data examination and two analyses showed that the updated DRWP meets the specifications in the OAT test plan and performs at least as well as the previous DRWP. Data examination verified that the DRWP provides complete profiles every five minutes from 1.8-19.5 km in vertical increments of 150 m. Analysis of 5,426 wind component reports from 49 concurrent DRWP and balloon profiles presented root mean square (RMS) wind component differences around 2.0 m/s. The DRWP's effective vertical resolution (EVR) was found to be 300 m for both the westerly and southerly wind component, which the best EVR possible given the DRWP's vertical sampling interval. A third analysis quantified the sensitivity to rejecting data that do not have adequate signal by assessing the number of first-guess propagations at each altitude. This report documents the data, quality control procedures, methodology, and results of each analysis. It also shows that analysis of the updated DRWP produced results that were at least as good as the previous DRWP with proper rationale. The report recommends acceptance of the updated DRWP for situational awareness usage as per the OAT's intent.

Short philtrum

MedlinePlus

... Textbook of Pediatrics . 20th ed. Philadelphia, PA: Elsevier; 2016:chap 125. Jones KL, Jones MC, Del Campo M. Facial-limb defects as major feature. In: Jones KL, Jones MC, Del Campo M, eds. Smith's Recognizable Patterns of Human ... Updated by: Neil K. Kaneshiro, MD, MHA, Clinical ...

75 FR 13313 - Advisory Committee for International Science and Engineering; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... NATIONAL SCIENCE FOUNDATION Advisory Committee for International Science and Engineering; Notice... Science and Engineering ( 25104). Date/Time: April 19, 2010--8:30 a.m. to 5 p.m. April 20, 2010--8:30 a.m... Engineering. Agenda April 19, 2010 AM: Introductions and Updates--Presentation and Discussion of 2010...

76 FR 15055 - Advisory Committee on Minority Veterans; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

.... until 4:15 p.m.; and April 8, 8 a.m. until 3 p.m. VA Medical Center, 50 Irving Street, NW., Washington... whether VA compensation, medical and rehabilitation services, outreach, and other programs are meeting..., the Committee will receive briefings and updates on the roles of the advisory committee, ethics...

77 FR 15053 - Manual for Courts-Martial; Proposed Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-14

... the M.R.E. and a Word document using color-coded text and comments to explain amendments. Updated... evidence. f. Commenter recommended using the words ``pursuant to statutory authority'' in M.R.E. 807. JSC... the rule to findings. i. Commenter recommended removing the word ``allegedly'' from proposed M.R.E...

77 FR 75150 - Department of Defense Task Force on the Care, Management, and Transition of Recovering Wounded...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

... Research and Materiel Command TBI Research Efforts Briefing 10:30 a.m.-11:30 a.m. Veteran Affairs VR&E... Health Affairs (HA) 2:30 p.m.-2:45 p.m. Break 2:45 p.m.-4:45 p.m. Defense Centers of Health on Psychological Health and Traumatic Brain Injury (DCoE PH and TBI) Updates 4:45 p.m.-5:00 p.m. Wrap Up Public's...

Testing an Earthquake Prediction Algorithm: The 2016 New Zealand and Chile Earthquakes

NASA Astrophysics Data System (ADS)

Kossobokov, Vladimir G.

2017-05-01

The 13 November 2016, M7.8, 54 km NNE of Amberley, New Zealand and the 25 December 2016, M7.6, 42 km SW of Puerto Quellon, Chile earthquakes happened outside the area of the on-going real-time global testing of the intermediate-term middle-range earthquake prediction algorithm M8, accepted in 1992 for the M7.5+ range. Naturally, over the past two decades, the level of registration of earthquakes worldwide has grown significantly and by now is sufficient for diagnosis of times of increased probability (TIPs) by the M8 algorithm on the entire territory of New Zealand and Southern Chile as far as below 40°S. The mid-2016 update of the M8 predictions determines TIPs in the additional circles of investigation (CIs) where the two earthquakes have happened. Thus, after 50 semiannual updates in the real-time prediction mode, we (1) confirm statistically approved high confidence of the M8-MSc predictions and (2) conclude a possibility of expanding the territory of the Global Test of the algorithms M8 and MSc in an apparently necessary revision of the 1992 settings.

Recent advancements in photorefractive holographic imaging

NASA Astrophysics Data System (ADS)

Lynn, B.; Blanche, P.-A.; Bablumian, A.; Rankin, R.; Voorakaranam, R.; St. Hilaire, P.; LaComb, L., Jr.; Yamamoto, M.; Peyghambarian, N.

2013-02-01

We have recently demonstrated several improvements in material properties and optical design to increase the resolution, size, brightness, and color range of updatable holograms using photorefractive materials. A compact system has been developed that is capable of producing holograms with brightness in excess of 2,500 cd/m2 using less than 20mW of CW laser power. The size of the hologram has been increased to 300mm × 150mm with a writing time of less than 8 seconds using a 50 Hz pulse laser. Optical improvements have been implemented to reduce the hogel size to less than 200 μm. We have optimized the color gamut to extend beyond the NTSC CIE color space through a combination of spatial and polarization multiplexing. Further improvements could bring applications in telemedicine, prototyping, advertising, updatable 3D maps and entertainment.

Tamper-Resistant Mobile Health Using Blockchain Technology

PubMed Central

2017-01-01

Background Digital health technologies, including telemedicine, mobile health (mHealth), and remote monitoring, are playing a greater role in medical practice. Safe and accurate management of medical information leads to the advancement of digital health, which in turn results in a number of beneficial effects. Furthermore, mHealth can help lower costs by facilitating the delivery of care and connecting people to their health care providers. Mobile apps help empower patients and health care providers to proactively address medical conditions through near real-time monitoring and treatment, regardless of the location of the patient or the health care provider. Additionally, mHealth data are stored in servers, and consequently, data management that prevents all forms of manipulation is crucial for both medical practice and clinical trials. Objective The aim of this study was to develop and evaluate a tamper-resistant mHealth system using blockchain technology, which enables trusted and auditable computing using a decentralized network. Methods We developed an mHealth system for cognitive behavioral therapy for insomnia using a smartphone app. The volunteer data collected with the app were stored in JavaScript Object Notation format and sent to the blockchain network. Thereafter, we evaluated the tamper resistance of the data against the inconsistencies caused by artificial faults. Results Electronic medical records collected using smartphones were successfully sent to a private Hyperledger Fabric blockchain network. We verified the data update process under conditions where all the validating peers were running normally. The mHealth data were successfully updated under network faults. We further ensured that any electronic health record registered to the blockchain network was resistant to tampering and revision. The mHealth data update was compatible with tamper resistance in the blockchain network. Conclusions Blockchain serves as a tamperproof system for mHealth. Combining mHealth with blockchain technology may provide a novel solution that enables both accessibility and data transparency without a third party such as a contract research organization. PMID:28747296

78 FR 79471 - Discretionary Advisory Committee on Heritable Disorders in Newborns and Children; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-30

..., 2014, 10:00 a.m. to 3:30 p.m. Place: Virtual via Webinar. Status: The meeting is open to the public...) updates from the Committee's subcommittees and ad-hoc workgroups including Laboratory Standards and...

Autoimmune hepatitis

MedlinePlus

... and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 90. Pawlotsky J-M. Chronic viral and autoimmune hepatitis. In: Goldman L, ... Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 149. ... Updated by: Michael M. Phillips, MD, Clinical Professor of Medicine, The George ...

75 FR 10507 - Advisory Committee for Biological Sciences; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-08

....: Introductions and Updates, Presentation and Discussion-- 2011 Budget Report; Undergraduate Education; Collections; and Dimensions of Biodiversity. p.m.: Presentation and Discussion--The Future of Biology; Advances in Sequencing Technology; COV Report; Committee Discussion. March 18, 2010 a.m.: Presentation and...

Efficient reporting of the estimated glomerular filtration rate without height in pediatric patients with cancer.

PubMed

Jeong, Tae-Dong; Cho, Eun-Jung; Lee, Woochang; Chun, Sail; Hong, Ki-Sook; Min, Won-Ki

2017-10-26

The updated bedside Schwartz equation requires constant, serum creatinine concentration and height measurements to calculate the estimated glomerular filtration rate (eGFR) in pediatric patients. Unlike the serum creatinine levels, obtaining height information from the laboratory information system (LIS) is not always possible in a clinical laboratory. Recently, the height-independent eGFR equation, the full age spectrum (FAS) equation, has been introduced. We evaluated the performance of height-independent eGFR equation in Korean children with cancer. A total of 250 children who underwent chromium-51-ethylenediamine tetra acetic-acid (51Cr-EDTA)-based glomerular filtration rate (GFR) measurements were enrolled. The 51Cr-EDTA GFR was used as the reference GFR. The bias (eGFR - measured GFR), precision (root mean square error [RMSE]) and accuracy (P30) of the FAS equations were compared to those of the updated Schwartz equation. P30 was defined as the percentage of patients whose eGFR was within ±30% of the measured GFR. The FAS equation showed significantly lower bias (mL/min/1.73 m2) than the updated Schwartz equation (4.2 vs. 8.7, p<0.001). The RMSE and P30 were: updated Schwartz of 43.8 and 64.4%, respectively, and FAS of 42.7 and 66.8%, respectively. The height-independent eGFR-FAS equation was less biased and as accurate as the updated Schwartz equation in Korean children. The use of the height-independent eGFR equation will allow for efficient reporting of eGFR through the LIS in clinical laboratories.

Updated Eastern Interconnect Wind Power Output and Forecasts for ERGIS: July 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pennock, K.

AWS Truepower, LLC (AWST) was retained by the National Renewable Energy Laboratory (NREL) to update wind resource, plant output, and wind power forecasts originally produced by the Eastern Wind Integration and Transmission Study (EWITS). The new data set was to incorporate AWST's updated 200-m wind speed map, additional tall towers that were not included in the original study, and new turbine power curves. Additionally, a primary objective of this new study was to employ new data synthesis techniques developed for the PJM Renewable Integration Study (PRIS) to eliminate diurnal discontinuities resulting from the assimilation of observations into mesoscale model runs.more » The updated data set covers the same geographic area, 10-minute time resolution, and 2004?2006 study period for the same onshore and offshore (Great Lakes and Atlantic coast) sites as the original EWITS data set.« less

Updates on the Performance and Calibration of HST/STIS

NASA Astrophysics Data System (ADS)

Lockwood, Sean A.; Monroe, TalaWanda R.; Ogaz, Sara; Branton, Doug; Carlberg, Joleen K.; Debes, John H.; Jedrzejewski, Robert I.; Proffitt, Charles R.; Riley, Allyssa; Sohn, Sangmo Tony; Sonnentrucker, Paule; Walborn, Nolan R.; Welty, Daniel

2018-06-01

The Space Telescope Imaging Spectrograph (STIS) on the Hubble Space Telescope (HST) has been in orbit for 21 years and continues to produce high quality scientific results using a diverse complement of operating modes. These include spatially resolved spectroscopy in the UV and optical, high spatial resolution echelle spectroscopy in the UV, and solar-blind imaging in the UV. In addition, STIS possesses unique visible-light coronagraphic modes that keep the instrument at the forefront of exoplanet and debris-disk research. As the instrument's characteristics evolve over its lifetime, the instrument team at the Space Telescope Science Institute monitors its performance and works towards improving the quality of its data products. Here we present updates on the status of the STIS CCD and FUV & NUV MAMA detectors, as well as changes to the CalSTIS reduction pipeline. We also discuss progress toward the recalibration of the E140M/1425 echelle mode. The E140M grating blaze function shapes have changed since flux calibration was carried out following SM4, which limits the relative photometric flux accuracy of some spectral orders up to 5-10% at the edges. In Cycle 25 a special calibration program was executed to obtain updated sensitivity curves for the E140M/1425 setting.

76 FR 27375 - Medical Review Board Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-11

... Period 11:45A-12:45 p.m. Break for Lunch 12:45-2 p.m. Update on 2007 Evidence Report on Sleep Apnea; Overview of 2007 Medical Expert Panel Opinions on Sleep Apnea 2-2:30 p.m. Review on Previous MRB recommendations on Sleep Apnea 2:30 -4 p.m. Public Comment Period Breaks will be announced on meeting day and may...

76 FR 80915 - Environmental Management Site-Specific Advisory Board, Northern New Mexico

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-27

...), Ed Worth and Lee Bishop Welcome and Introductions, Ralph Phelps 3:15 p.m. Environmental Cleanup.... Consent Order Update 6 p.m. Public Comment Period, Ralph Phelps 7 p.m. Adjourn, Lee Bishop and Ed Worth... presentation in the agenda. The Deputy Designated Federal Officer is empowered to conduct the meeting in a...

78 FR 9743 - Advisory Committee for Environmental Research and Education; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... NSF's Science, Engineering and Education for Sustainability portfolio (SEES) March 14, 2013 Update on... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... and Education, 9487. Dates: March 13, 2013, 9:00 a.m.-5:00 p.m., and March 14, 2013, 9:00 a.m.-2:00 p...

77 FR 53192 - Environmental Management Site-Specific Advisory Board, Northern New Mexico

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-31

... Annual Self-Evaluation 2:30 p.m. Items from the DDFO, Ed Worth Update from DOE Other Items 2:45 p.m... Protection Agency (Region 6), Ed Worth for Rich Mayer Data Input and Validation and Verification Process 4:15...

"Big Data Assimilation" for 30-second-update 100-m-mesh Numerical Weather Prediction

NASA Astrophysics Data System (ADS)

Miyoshi, Takemasa; Lien, Guo-Yuan; Kunii, Masaru; Ruiz, Juan; Maejima, Yasumitsu; Otsuka, Shigenori; Kondo, Keiichi; Seko, Hiromu; Satoh, Shinsuke; Ushio, Tomoo; Bessho, Kotaro; Kamide, Kazumi; Tomita, Hirofumi; Nishizawa, Seiya; Yamaura, Tsuyoshi; Ishikawa, Yutaka

2017-04-01

A typical lifetime of a single cumulonimbus is within an hour, and radar observations often show rapid changes in only a 5-minute period. For precise prediction of such rapidly-changing local severe storms, we have developed what we call a "Big Data Assimilation" (BDA) system that performs 30-second-update data assimilation cycles at 100-m grid spacing. The concept shares that of NOAA's Warn-on-Forecast (WoF), in which rapidly-updated high-resolution NWP will play a central role in issuing severe-storm warnings even only minutes in advance. The 100-m resolution and 30-second update frequency are a leap above typical recent research settings, and it was possible by the fortunate combination of Japan's most advanced supercomputing and sensing technologies: the 10-petaflops K computer and the Phased Array Weather Radar (PAWR). The X-band PAWR is capable of a dense three-dimensional volume scan at 100-m range resolution with 100 elevation angles and 300 azimuth angles, up to 60-km range within 30 seconds. The PAWR data show temporally-smooth evolution of convective rainstorms. This gives us a hope that we may assume the Gaussian error distribution in 30-second forecasts before strong nonlinear dynamics distort the error distribution for rapidly-changing convective storms. With this in mind, we apply the Local Ensemble Transform Kalman Filter (LETKF) that considers flow-dependent error covariance explicitly under the Gaussian-error assumption. The flow-dependence would be particularly important in rapidly-changing convective weather. Using a 100-member ensemble at 100-m resolution, we have tested the Big Data Assimilation system in real-world cases of sudden local rainstorms, and obtained promising results. However, the real-time application is a big challenge, and currently it takes 10 minutes for a cycle. We explore approaches to accelerating the computations, such as using single-precision arrays in the model computation and developing an efficient I/O middleware for passing the large data between model and data assimilation as quickly as possible. In this presentation, we will present the most up-to-date progress of our Big Data Assimilation research.

An update on the study of high-gradient elliptical SRF cavities at 805 MHz for proton and other applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tajima, Tsuyoshi; Haynes, Brian; Krawczyk, Frank

2010-09-09

An update on the study of 805 MHz elliptical SRF cavities that have been optimized for high gradient will be presented. An optimized cell shape, which is still appropriate for easy high pressure water rinsing, has been designed with the ratios of peak magnetic and electric fields to accelerating gradient being 3.75 mT/(MV/m) and 1.82, respectively. A total of 3 single-cell cavities have been fabricated. Two of the 3 cavities have been tested so far. The second cavity achieved an E{sub acc} of {approx}50 MV/m at Q{sub 0} of 1.4 x 10{sup 10}. This result demonstrates that 805 MHz cavitiesmore » can, in principle, achieve as high as, or could even be better than, 1.3 GHz high-gradient cavities.« less

Optimisation of quantitative lung SPECT applied to mild COPD: a software phantom simulation study.

PubMed

Norberg, Pernilla; Olsson, Anna; Alm Carlsson, Gudrun; Sandborg, Michael; Gustafsson, Agnetha

2015-01-01

The amount of inhomogeneities in a (99m)Tc Technegas single-photon emission computed tomography (SPECT) lung image, caused by reduced ventilation in lung regions affected by chronic obstructive pulmonary disease (COPD), is correlated to disease advancement. A quantitative analysis method, the CVT method, measuring these inhomogeneities was proposed in earlier work. To detect mild COPD, which is a difficult task, optimised parameter values are needed. In this work, the CVT method was optimised with respect to the parameter values of acquisition, reconstruction and analysis. The ordered subset expectation maximisation (OSEM) algorithm was used for reconstructing the lung SPECT images. As a first step towards clinical application of the CVT method in detecting mild COPD, this study was based on simulated SPECT images of an advanced anthropomorphic lung software phantom including respiratory and cardiac motion, where the mild COPD lung had an overall ventilation reduction of 5%. The best separation between healthy and mild COPD lung images as determined using the CVT measure of ventilation inhomogeneity and 125 MBq (99m)Tc was obtained using a low-energy high-resolution collimator (LEHR) and a power 6 Butterworth post-filter with a cutoff frequency of 0.6 to 0.7 cm(-1). Sixty-four reconstruction updates and a small kernel size should be used when the whole lung is analysed, and for the reduced lung a greater number of updates and a larger kernel size are needed. A LEHR collimator and 125 (99m)Tc MBq together with an optimal combination of cutoff frequency, number of updates and kernel size, gave the best result. Suboptimal selections of either cutoff frequency, number of updates and kernel size will reduce the imaging system's ability to detect mild COPD in the lung phantom.

The 2018 and 2020 Updates of the U.S. National Seismic Hazard Models

NASA Astrophysics Data System (ADS)

Petersen, M. D.

2017-12-01

During 2018 the USGS will update the 2014 National Seismic Hazard Models by incorporating new seismicity models, ground motion models, site factors, fault inputs, and by improving weights to ground motion models using empirical and other data. We will update the earthquake catalog for the U.S. and introduce new rate models. Additional fault data will be used to improve rate estimates on active faults. New ground motion models (GMMs) and site factors for Vs30 have been released by the Pacific Earthquake Engineering Research Center (PEER) and we will consider these in assessing ground motions in craton and extended margin regions of the central and eastern U.S. The USGS will also include basin-depth terms for selected urban areas of the western United States to improve long-period shaking assessments using published depth estimates to 1.0 and 2.5 km/s shear wave velocities. We will produce hazard maps for input into the building codes that span a broad range of periods (0.1 to 5 s) and site classes (shear wave velocity from 2000 m/s to 200 m/s in the upper 30 m of the crust, Vs30). In the 2020 update we plan on including: a new national crustal model that defines basin depths required in the latest GMMs, new 3-D ground motion simulations for several urban areas, new magnitude-area equations, and new fault geodetic and geologic strain rate models. The USGS will also consider including new 3-D ground motion simulations for inclusion in these long-period maps. These new models are being evaluated and will be discussed at one or more regional and topical workshops held at the beginning of 2018.

Large-Area Visually Augmented Navigation for Autonomous Underwater Vehicles

DTIC Science & Technology

2005-06-01

constrain position drift . Correction of errors in position and orientation are made each time the mosaic is updated, which occurs every Lth video frame. They...are the greatest strength of a VAN methodology. It is these measurements which help to correct dead-reckoned drift error and enforce recovery of a...systems. [INSTRUMENT [VARIABLE I INTENAL? I UPDATE RATE PRECISION FRANGE J DRIFT Acoustic Altimeter Z - Altitude yes varies: 0.1-10 Hz 0.01-1.0 m varies

75 FR 60132 - National Cancer Institute; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... a.m. to 12 p.m. Agenda: Director's Update; Emerging Opportunities in Gen and Target-Based Research... Target-Based Research Approaches in the Research Paradigm. Place: National Institutes of Health, Building... Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399, Cancer Control...

The effect of ageing on recollection: the role of the binding updating process.

PubMed

Boujut, Arnaud; Clarys, David

2016-10-01

The aim of this study was to highlight the underlying process responsible for the age-related deficit in recollection. Through two experiments using the Remember-Know-Guess procedure (Gardiner, J. M., & Richardson-Klavehn, A. [2000]. Remembering and knowing. In The Oxford handbook of memory (pp. 229-244). New York, NY: Oxford University Press) in recognition, we manipulated the opportunity to update bindings between target items and their encoding context, in young and older adults. In the first experiment we impaired the binding updating process during the encoding of items, while in the second we supported this process. The results indicated that the "Remember" responses in the younger group were specifically reduced by the impairment of the binding updating process (Exp. 1), suggesting that this ability is useful for them to encode a specific episode. Conversely, only the "Remember" responses in the older group were improved in accuracy by supporting the binding updating process (Exp. 2), suggesting that their weakness in this ability is the source of their failure to improve the accuracy of their memories. The overall results support the hypothesis that the age-related decline in episodic memory is partly due to a greater vulnerability to interference on bindings, impairing the ability to update content-context bindings as and when events occur.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramuhalli, Pradeep; Hirt, Evelyn H.; Veeramany, Arun

This research report summaries the development and evaluation of a prototypic enhanced risk monitor (ERM) methodology (framework) that includes alternative risk metrics and uncertainty analysis. This updated ERM methodology accounts for uncertainty in the equipment condition assessment (ECA), the prognostic result, and the probabilistic risk assessment (PRA) model. It is anticipated that the ability to characterize uncertainty in the estimated risk and update the risk estimates in real time based on equipment condition assessment (ECA) will provide a mechanism for optimizing plant performance while staying within specified safety margins. These results (based on impacting active component O&M using real-time equipmentmore » condition information) are a step towards ERMs that, if integrated with AR supervisory plant control systems, can help control O&M costs and improve affordability of advanced reactors.« less

New Critical Compilations of Atomic Transition Probabilities for Neutral and Singly Ionized Carbon, Nitrogen, and Iron

NASA Technical Reports Server (NTRS)

Wiese, Wolfgang L.; Fuhr, J. R.

2006-01-01

We have undertaken new critical assessments and tabulations of the transition probabilities of important lines of these spectra. For Fe I and Fe II, we have carried out a complete re-assessment and update, and we have relied almost exclusively on the literature of the last 15 years. Our updates for C I, C II and N I, N II primarily address the persistent lower transitions as well as a greatly expanded number of forbidden lines (M1, M2, and E2). For these transitions, sophisticated multiconfiguration Hartree-Fock (MCHF) calculations have been recently carried out, which have yielded data considerably improved and often appreciably different from our 1996 NIST compilation.

Revised coordinates of the Mars Orbiter Laser Altimeter (MOLA) footprints

NASA Astrophysics Data System (ADS)

Annibali, S.; Stark, A.; Gwinner, K.; Hussmann, H.; Oberst, J.

2017-09-01

We revised the Mars Orbiter Laser Altimeter (MOLA) footprint locations (i.e. areocentric body-fixed latitude and longitude), using updated trajectory models for the Mars Global Surveyor and updated rotation parameters of Mars, including precession, nutation and length-of-day variation. We assess the impact of these updates on the gridded MOLA maps. A first comparison reveals that even slight corrections to the rotational state of Mars can lead to height differences up to 100 m (in particular in regions with high slopes, where large interpolation effects are expected). Ultimately, we aim at independent measurements of the rotation parameters of Mars. We co-register MOLA profiles to digital terrain models from stereo images (stereo DTMs) and measure offsets of the two data sets.

The pH-dependent surface charging and points of zero charge: V. Update.

PubMed

Kosmulski, Marek

2011-01-01

The points of zero charge (PZC) and isoelectric points (IEP) from the recent literature are discussed. This study is an update of the previous compilation [M. Kosmulski, Surface Charging and Points of Zero Charge, CRC, Boca Raton, FL, 2009] and of its previous update [J. Colloid Interface Sci. 337 (2009) 439]. In several recent publications, the terms PZC/IEP have been used outside their usual meaning. Only the PZC/IEP obtained according to the methods recommended by the present author are reported in this paper, and the other results are ignored. PZC/IEP of albite, sepiolite, and sericite, which have not been studied before, became available over the past 2 years. Copyright © 2010 Elsevier Inc. All rights reserved.

Improving the representation of secondary organic aerosol (SOA) in the MOZART-4 global chemical transport model

NASA Astrophysics Data System (ADS)

Mahmud, A.; Barsanti, K. C.

2012-12-01

The secondary organic aerosol (SOA) module in the Model for Ozone and Related chemical Tracers, version 4 (MOZART-4) has been updated by replacing existing two-product (2p) parameters with those obtained from two-product volatility basis set (2p-VBS) fits, and by treating SOA formation from the following volatile organic compounds (VOCs): isoprene, propene and lumped alkenes. Strong seasonal and spatial variations in global SOA distributions were demonstrated, with significant differences in the predicted concentrations between the base-case and updated model versions. The base-case MOZART-4 predicted annual average SOA of 0.36 ± 0.50 μg m-3 in South America, 0.31 ± 0.38 μg m-3 in Indonesia, 0.09 ± 0.05 μg m-3 in the USA, and 0.12 ± 0.07 μg m-3 in Europe. Concentrations from the updated versions of the model showed a~marked increase in annual average SOA. Using the updated set of parameters alone (MZ4-v1) increased annual average SOA by ~8%, ~16%, ~56%, and ~108% from the base-case in South America, Indonesia, USA, and Europe, respectively. Treatment of additional parent VOCs (MZ4-v2) resulted in an even more dramatic increase of ~178-406% in annual average SOA for these regions over the base-case. The increases in predicted SOA concentrations further resulted in increases in corresponding SOA contributions to annual average total aerosol optical depth (AOD) by <1% for MZ4-v1 and ~1-6% for MZ4-v2. Estimated global SOA production was ~6.6 Tg yr-1 and ~19.1 Tg yr-1 with corresponding burdens of ~0.24 Tg and ~0.59 Tg using MZ4-v1 and MZ4-v2, respectively. The SOA budgets predicted in the current study fall well within reported ranges for similar modeling studies, 6.7 to 96 Tg yr-1, but are lower than recently reported observationally-constrained values, 50 to 380 Tg yr-1. With MZ4-v2, simulated SOA concentrations at the surface were also in reasonable agreement with comparable modeling studies and observations. Concentrations of estimated organic aerosol (OA) at the surface, however, showed under-prediction in Europe and over-prediction in the Amazonian regions and Malaysian Borneo during certain months of the year. Overall, the updated version of MOZART-4, MZ4-v2, showed consistently better skill in predicting SOA and OA levels and spatial distributions as compared with unmodified MOZART-4. The MZ4-v2 updates may be particularly important when MOZART-4 output is used to generate boundary conditions for regional air quality simulations that require more accurate representation of SOA concentrations and distributions.

78 FR 31525 - National Security Education Board; Notice of Federal Advisory Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-24

... Security Education Program Service Requirements Updates. 4:45 p.m.--Board Discussion. 5:30 p.m.--Adjourn... DEPARTMENT OF DEFENSE Office of the Secretary National Security Education Board; Notice of Federal... and National Security Education Office (DLNSEO), DoD. ACTION: Meeting notice. SUMMARY: Under the...

75 FR 50009 - Advisory Committee for Environmental Research and Education; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-16

... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... and Education (9487). Dates: September 8, 2010-September 9, 2010, 8:30 a.m.-1 p.m. Place: Stafford I... support for environmental research and education. Agenda September 8, 2010 Update on recent NSF...

78 FR 40069 - Airworthiness Directives; Airbus Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-03

... and an updated fatigue and damage tolerance analysis that the risk for fatigue cracking on the front... and correct fatigue cracks in the bolt holes of the wing spars, which could result in reduced..., between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. For service information...

75 FR 39008 - Environmental Management Site-Specific Advisory Board, Idaho National Laboratory

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-07

... Dry Storage. Waste Area Group--7 Update. In-Situ Grouting. Comment Resolution--Environmental... meeting be announced in the Federal Register. DATES: Wednesday, July 14, 2010 8 a.m.-5 p.m. Opportunities... management in the areas of environmental restoration, waste management, and related activities. Tentative...

77 FR 11594 - Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-27

...: March 9, 2012, 9 a.m.-5 p.m. Location: 1177 Avenue of the Americas, New York, NY 10036. Status: The... several funding proposals including a project focused on the subminimum wage and competitive integrated... at Syracuse University, to provide an update on emerging issues in regards to disability law, policy...

Babinski reflex

MedlinePlus

... examination. In: Malanga GA, Mautner K, eds. Musculoskeletal Physical Examination: An Evidence-Based Approach . 2nd ed. Philadelphia, PA: Elsevier; 2017:chap 2. Review Date 2/23/2017 Updated by: Amit M. ...

Improved meteorology from an updated WRF/CMAQ modeling ...

EPA Pesticide Factsheets

Realistic vegetation characteristics and phenology from the Moderate Resolution Imaging Spectroradiometer (MODIS) products improve the simulation for the meteorology and air quality modeling system WRF/CMAQ (Weather Research and Forecasting model and Community Multiscale Air Quality model) that employs the Pleim-Xiu land surface model (PX LSM). Recently, PX LSM WRF/CMAQ has been updated in vegetation, soil, and boundary layer processes resulting in improved 2 m temperature (T) and mixing ratio (Q), 10 m wind speed, and surface ozone simulations across the domain compared to the previous version for a period around August 2006. Yearlong meteorology simulations with the updated system demonstrate that MODIS input helps reduce bias of the 2 m Q estimation during the growing season from April to September. Improvements follow the green-up in the southeast from April and move toward the west and north through August. From October to March, MODIS input does not have much influence on the system because vegetation is not as active. The greatest effects of MODIS input include more accurate phenology, better representation of leaf area index (LAI) for various forest ecosystems and agricultural areas, and realistically sparse vegetation coverage in the western drylands. Despite the improved meteorology, MODIS input causes higher bias for the surface O3 simulation in April, August, and October in areas where MODIS LAI is much less than the base LAI. Thus, improvement

Numbness and tingling

MedlinePlus

... nervous system. In: Swartz MH, ed. Textbook of Physical Diagnosis: History and Examination . 7th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 18. Review Date 5/15/2017 Updated by: Amit M. ...

Gallstones

MedlinePlus

... ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 155. Jackson PG, Evans SRT. Biliary system. In: Townsend CM ... 65. Review Date 4/19/2017 Updated by: Michael M. Phillips, MD, Clinical Professor of Medicine, The ...

Insomnia

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Schizophrenia

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Agoraphobia

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

75 FR 6699 - Boston Harbor Islands National Recreation Area Advisory Council; Notice of Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... on Wednesday, March 3, 2010, at 6 p.m. to 8 p.m. at the Boston Public Library, 700 Boylston Street... other council business, a park update, and public comment. The meeting will be open to the public. Any... guarantee that we will be able to do so. DATES: March 3, 2010 at 6 p.m. ADDRESSES: Boston Public Library...

78 FR 27256 - Meeting of the California Desert District Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-09

..., from 8 a.m. to 4:30 p.m. in Ridgecrest, Calif. at a location to be announced later. There also will be a DAC Business Meeting on Friday, June 7, from noon to 4:30 p.m. at the Jawbone Station Visitors... Saturday meeting will include a focus on the West Mojave Plan, as well as updates by council members, the...

Landsat-7 ETM+ Radiometric Calibration Status

NASA Technical Reports Server (NTRS)

Barsi, Julia A.; Markham, Brian L.; Czapla-Myers, Jeffrey S.; Helder, Dennis L.; Hook, Simon J.; Schott, John R; Haque, Md. Obaidul

2016-01-01

Now in its 17th year of operation, the Enhanced Thematic Mapper + (ETM+), on board the Landsat-7 satellite, continues to systematically acquire imagery of the Earth to add to the 40+ year archive of Landsat data. Characterization of the ETM+ on-orbit radiometric performance has been on-going since its launch in 1999. The radiometric calibration of the reflective bands is still monitored using on-board calibration devices, though the Pseudo-Invariant Calibration Sites (PICS) method has proven to be an effect tool as well. The calibration gains were updated in April 2013 based primarily on PICS results, which corrected for a change of as much as -0.2%/year degradation in the worst case bands. A new comparison with the SADE database of PICS results indicates no additional degradation in the updated calibration. PICS data are still being tracked though the recent trends are not well understood. The thermal band calibration was updated last in October 2013 based on a continued calibration effort by NASA/Jet Propulsion Lab and Rochester Institute of Technology. The update accounted for a 0.31 W/sq m/ sr/micron bias error. The updated lifetime trend is now stable to within + 0.4K.

Tamper-Resistant Mobile Health Using Blockchain Technology.

PubMed

Ichikawa, Daisuke; Kashiyama, Makiko; Ueno, Taro

2017-07-26

Digital health technologies, including telemedicine, mobile health (mHealth), and remote monitoring, are playing a greater role in medical practice. Safe and accurate management of medical information leads to the advancement of digital health, which in turn results in a number of beneficial effects. Furthermore, mHealth can help lower costs by facilitating the delivery of care and connecting people to their health care providers. Mobile apps help empower patients and health care providers to proactively address medical conditions through near real-time monitoring and treatment, regardless of the location of the patient or the health care provider. Additionally, mHealth data are stored in servers, and consequently, data management that prevents all forms of manipulation is crucial for both medical practice and clinical trials. The aim of this study was to develop and evaluate a tamper-resistant mHealth system using blockchain technology, which enables trusted and auditable computing using a decentralized network. We developed an mHealth system for cognitive behavioral therapy for insomnia using a smartphone app. The volunteer data collected with the app were stored in JavaScript Object Notation format and sent to the blockchain network. Thereafter, we evaluated the tamper resistance of the data against the inconsistencies caused by artificial faults. Electronic medical records collected using smartphones were successfully sent to a private Hyperledger Fabric blockchain network. We verified the data update process under conditions where all the validating peers were running normally. The mHealth data were successfully updated under network faults. We further ensured that any electronic health record registered to the blockchain network was resistant to tampering and revision. The mHealth data update was compatible with tamper resistance in the blockchain network. Blockchain serves as a tamperproof system for mHealth. Combining mHealth with blockchain technology may provide a novel solution that enables both accessibility and data transparency without a third party such as a contract research organization. ©Daisuke Ichikawa, Makiko Kashiyama, Taro Ueno. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 26.07.2017.

Comparison of two optimization algorithms for fuzzy finite element model updating for damage detection in a wind turbine blade

NASA Astrophysics Data System (ADS)

Turnbull, Heather; Omenzetter, Piotr

2018-03-01

vDifficulties associated with current health monitoring and inspection practices combined with harsh, often remote, operational environments of wind turbines highlight the requirement for a non-destructive evaluation system capable of remotely monitoring the current structural state of turbine blades. This research adopted a physics based structural health monitoring methodology through calibration of a finite element model using inverse techniques. A 2.36m blade from a 5kW turbine was used as an experimental specimen, with operational modal analysis techniques utilised to realize the modal properties of the system. Modelling the experimental responses as fuzzy numbers using the sub-level technique, uncertainty in the response parameters was propagated back through the model and into the updating parameters. Initially, experimental responses of the blade were obtained, with a numerical model of the blade created and updated. Deterministic updating was carried out through formulation and minimisation of a deterministic objective function using both firefly algorithm and virus optimisation algorithm. Uncertainty in experimental responses were modelled using triangular membership functions, allowing membership functions of updating parameters (Young's modulus and shear modulus) to be obtained. Firefly algorithm and virus optimisation algorithm were again utilised, however, this time in the solution of fuzzy objective functions. This enabled uncertainty associated with updating parameters to be quantified. Varying damage location and severity was simulated experimentally through addition of small masses to the structure intended to cause a structural alteration. A damaged model was created, modelling four variable magnitude nonstructural masses at predefined points and updated to provide a deterministic damage prediction and information in relation to the parameters uncertainty via fuzzy updating.

Gender dysphoria

MedlinePlus

... Psychiatry Committee on Quality Issues. Practice parameter on gay, lesbian, or bisexual sexual orientation, gender nonconformity, and ... M. Editorial team. Editorial update 08/15/2016. Gay, Lesbian, Bisexual, and Transgender Health Read more NIH ...

Hand or foot spasms

MedlinePlus

... deficiency states. In: Swartz MH, ed. Textbook of Physical Diagnosis: History and Examination . 7th ed. Philadelphia, PA: Elsevier Saunders; 2014:Appendix B. Review Date 2/27/2016 Updated by: Amit M. ...

Adjustment disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Drug abuse

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Conversion disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Panic disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Personality disorders

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Indoor localization using pedestrian dead reckoning updated with RFID-based fiducials.

PubMed

House, Samuel; Connell, Sean; Milligan, Ian; Austin, Daniel; Hayes, Tamara L; Chiang, Patrick

2011-01-01

We describe a low-cost wearable system that tracks the location of individuals indoors using commonly available inertial navigation sensors fused with radio frequency identification (RFID) tags placed around the smart environment. While conventional pedestrian dead reckoning (PDR) calculated with an inertial measurement unit (IMU) is susceptible to sensor drift inaccuracies, the proposed wearable prototype fuses the drift-sensitive IMU with a RFID tag reader. Passive RFID tags placed throughout the smart-building then act as fiducial markers that update the physical locations of each user, thereby correcting positional errors and sensor inaccuracy. Experimental measurements taken for a 55 m × 20 m 2D floor space indicate an over 1200% improvement in average error rate of the proposed RFID-fused system over dead reckoning alone.

The MEarth Project: Status Update and the Commissioning of a Brand New Telescope Array in the Southern Hemisphere

NASA Astrophysics Data System (ADS)

Berta-Thompson, Zachory K.; Irwin, Jonathan; Charbonneau, David; Newton, Elisabeth R.; Dittmann, Jason

2014-06-01

The MEarth Project is an ongoing all-sky survey for Earth-like planets transiting the closest, smallest M dwarfs. MEarth aims to find good targets for atmospheric characterization with JWST and the next generation of enormous ground-based telescopes. MEarth's yearly data releases, containing precise light curves of nearby mid-to-late M dwarfs, provide a unique window into the photometric variability of the stars that will forever be among the most interesting targets in the search for potentially habitable exoplanets. We present a status update on the MEarth Project, including a detailed map of the progress we’ve made so far with 8 telescopes in the Northern hemisphere and promising early results from our new installation of 8 more telescopes in the Southern hemisphere.

Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines.

PubMed

Stacul, Fulvio; van der Molen, Aart J; Reimer, Peter; Webb, Judith A W; Thomsen, Henrik S; Morcos, Sameh K; Almén, Torsten; Aspelin, Peter; Bellin, Marie-France; Clement, Olivier; Heinz-Peer, Gertraud

2011-12-01

The Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) has updated its 1999 guidelines on contrast medium-induced nephropathy (CIN). Topics reviewed include the definition of CIN, the choice of contrast medium, the prophylactic measures used to reduce the incidence of CIN, and the management of patients receiving metformin. Key Points • Definition, risk factors and prevention of contrast medium induced nephropathy are reviewed. • CIN risk is lower with intravenous than intra-arterial iodinated contrast medium. • eGFR of 45 ml/min/1.73 m (2) is CIN risk threshold for intravenous contrast medium. • Hydration with either saline or sodium bicarbonate reduces CIN incidence. • Patients with eGFR ≥ 60 ml/min/1.73 m (2) receiving contrast medium can continue metformin normally.

Combining Multi-Source Remotely Sensed Data and a Process-Based Model for Forest Aboveground Biomass Updating.

PubMed

Lu, Xiaoman; Zheng, Guang; Miller, Colton; Alvarado, Ernesto

2017-09-08

Monitoring and understanding the spatio-temporal variations of forest aboveground biomass (AGB) is a key basis to quantitatively assess the carbon sequestration capacity of a forest ecosystem. To map and update forest AGB in the Greater Khingan Mountains (GKM) of China, this work proposes a physical-based approach. Based on the baseline forest AGB from Landsat Enhanced Thematic Mapper Plus (ETM+) images in 2008, we dynamically updated the annual forest AGB from 2009 to 2012 by adding the annual AGB increment (ABI) obtained from the simulated daily and annual net primary productivity (NPP) using the Boreal Ecosystem Productivity Simulator (BEPS) model. The 2012 result was validated by both field- and aerial laser scanning (ALS)-based AGBs. The predicted forest AGB for 2012 estimated from the process-based model can explain 31% ( n = 35, p < 0.05, RMSE = 2.20 kg/m²) and 85% ( n = 100, p < 0.01, RMSE = 1.71 kg/m²) of variation in field- and ALS-based forest AGBs, respectively. However, due to the saturation of optical remote sensing-based spectral signals and contribution of understory vegetation, the BEPS-based AGB tended to underestimate/overestimate the AGB for dense/sparse forests. Generally, our results showed that the remotely sensed forest AGB estimates could serve as the initial carbon pool to parameterize the process-based model for NPP simulation, and the combination of the baseline forest AGB and BEPS model could effectively update the spatiotemporal distribution of forest AGB.

Combining Multi-Source Remotely Sensed Data and a Process-Based Model for Forest Aboveground Biomass Updating

PubMed Central

Lu, Xiaoman; Zheng, Guang; Miller, Colton

2017-01-01

Monitoring and understanding the spatio-temporal variations of forest aboveground biomass (AGB) is a key basis to quantitatively assess the carbon sequestration capacity of a forest ecosystem. To map and update forest AGB in the Greater Khingan Mountains (GKM) of China, this work proposes a physical-based approach. Based on the baseline forest AGB from Landsat Enhanced Thematic Mapper Plus (ETM+) images in 2008, we dynamically updated the annual forest AGB from 2009 to 2012 by adding the annual AGB increment (ABI) obtained from the simulated daily and annual net primary productivity (NPP) using the Boreal Ecosystem Productivity Simulator (BEPS) model. The 2012 result was validated by both field- and aerial laser scanning (ALS)-based AGBs. The predicted forest AGB for 2012 estimated from the process-based model can explain 31% (n = 35, p < 0.05, RMSE = 2.20 kg/m2) and 85% (n = 100, p < 0.01, RMSE = 1.71 kg/m2) of variation in field- and ALS-based forest AGBs, respectively. However, due to the saturation of optical remote sensing-based spectral signals and contribution of understory vegetation, the BEPS-based AGB tended to underestimate/overestimate the AGB for dense/sparse forests. Generally, our results showed that the remotely sensed forest AGB estimates could serve as the initial carbon pool to parameterize the process-based model for NPP simulation, and the combination of the baseline forest AGB and BEPS model could effectively update the spatiotemporal distribution of forest AGB. PMID:28885556

The Making of the 1:3M Geological Map Series of Mercury: Status and Updates

NASA Astrophysics Data System (ADS)

Galluzzi, V.; Guzzetta, L.; Mancinelli, P.; Giacomini, L.; Lewang, A. M.; Malliband, C.; Mosca, A.; Pegg, D.; Wright, J.; Ferranti, L.; Hiesinger, H.; Massironi, M.; Pauselli, C.; Rothery, D. A.; Palumbo, P.

2018-05-01

A complete global series of 1:3M-scale maps of Mercury is being prepared in support to the ESA/JAXA BepiColombo mission. Currently, 35% of Mercury has been mapped and 55% of the planet will be covered soon by the maps in progress.

78 FR 48200 - Advisory Committee for Environmental Research and Education; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-07

... NATIONAL SCIENCE FOUNDATION Advisory Committee for Environmental Research and Education; Notice of... Research and Education, 9487. Dates: September 11, 2013, 9:00 a.m.-5:00 p.m., and September 12, 2013, 9:00... research and education. Agenda September 11, 2013 Update on NSF environmental research and education...

77 FR 31332 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-25

... consider changes to the 2013 quota specifications for surfclams and ocean quahogs and update PSP, data..., Mackerel, Squid, and Butterfish Committee, and its Surfclam, Ocean Quahog Committee will hold public... (Amendment 14) from 1 p.m. until 3 p.m. The Surfclam and Ocean Quahog Committee will meet as a Committee of...

75 FR 70904 - South Atlantic Fishery Management Council (Council); Public Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

... meetings. SUMMARY: The South Atlantic Fishery Management Council will hold a meeting of its Spiny Lobster....net . SUPPLEMENTARY INFORMATION: Meeting Dates 1. Spiny Lobster Committee: December 6, 2010, 1:30 p.m. Until 4:30 p.m. The Spiny Lobster Committee will review the SEDAR Spiny Lobster Update regarding the...

78 FR 28619 - Boston Harbor Islands Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-15

... DEPARTMENT OF THE INTERIOR [NPS-NER-BOHA-12921: PPMPSPD1Z.YM0000: PPNEBOHAS1] Boston Harbor.... SUMMARY: This notice announces a meeting of the Boston Harbor Islands Advisory Council. The agenda... park update. DATES: Date/Time: June 5, 2013, 4:00 p.m. to 6:00 p.m. (EASTERN). Location: Boston Society...

A data storage, retrieval and analysis system for endocrine research. [for Skylab

NASA Technical Reports Server (NTRS)

Newton, L. E.; Johnston, D. A.

1975-01-01

This retrieval system builds, updates, retrieves, and performs basic statistical analyses on blood, urine, and diet parameters for the M071 and M073 Skylab and Apollo experiments. This system permits data entry from cards to build an indexed sequential file. Programs are easily modified for specialized analyses.

75 FR 71465 - National Science Board; Sunshine Act Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-23

... Science Foundation, 4201 Wilson Blvd., Room 1235, Arlington, VA 22230. All visitors must report to the NSF... Session: 9:50 a.m.-11 a.m., Room 1235 Approval of Minutes. PCAST Report: Prepare and Inspire: K-12.... Update on NSF's Response to the STEM Innovators Report and Other Recent STEM Education Policy...

75 FR 44226 - Mid-Atlantic Fishery Management Council (MAFMC); Public Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-28

... the Interagency Ocean Policy Task Force. 10:45 a.m. to 1:30 p.m. - The Council will convene to conduct... the Ricks E Savage Award criteria and nomination process, excessive share project update, Scientific... recommendations of the Interagency Ocean Policy Task Force. The Council will hold its regular Business Session to...

77 FR 31330 - South Atlantic Fishery Management Council; Public Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-25

... Collection Committee; King and Spanish Mackerel Committee; Advisory Panel Selection Committee (Closed Session..., beginning at 5:30 p.m. 7. King and Spanish Mackerel Committee Meeting: June 14, 2012, 8:30 a.m. Until 12 Noon The King and Spanish Mackerel Committee will receive updates on the status of catches versus ACLs...

CMS MDS 3.0 Section M Skin Conditions in Long-term Care: Pressure Ulcers, Skin Tears, and Moisture-Associated Skin Damage Data Update.

PubMed

Ayello, Elizabeth A

2017-09-01

The purpose of this learning activity is to provide information about the updates to the Centers for Medicare & Medicaid Services (CMS) MDS 3.0 Section M, Skin Conditions documentation in long-term care. This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. After participating in this educational activity, the participant should be better able to:1. Explain the use of the CMS MDS 3.0 tool for documenting skin problems in long-term care.2. Demonstrate examples of proper documentation for specific skin problems. This manuscript reviews some of the key parts of the October 2016 revised Long-term Care Resident Assessment Instrument manual for Minimum Data Set (MDS) 3.0 Section M Skin Conditions. It also reports the Centers for Medicare & Medicaid's publicly reported frequency data in long-term care for selected items on the MDS 3.0 Section M Skin Conditions. Percentages and trends of pressure ulcers/injuries, skin tears, and moisture-associated skin damage are assessed.

Osteoarthritis

MedlinePlus

... Knee Osteoarthritis by DY Wen, M.D.(American Family Physician 08/01/00) Shoulder Osteoarthritis: Diagnosis and Management ... Gobezie, MD, and Robert E. Boykin, MD(American Family Physician 09/01/08) Last Updated: April 1, 2014 ...

Cholinesterase - blood

MedlinePlus

... ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 110. Review Date 5/15/2017 Updated by: Amit M. ... Stony Brook, School of Medicine, Stony Brook, NY. Review provided by VeriMed Healthcare Network. Also reviewed by ...

Illness anxiety disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Paranoid personality disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Avoidant personality disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Dependent personality disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Antisocial personality disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Generalized anxiety disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Phobia - simple/specific

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Schizotypal personality disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic Psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Testing the Model: A Phase 1/2 Randomized Double Blind Placebo Control Trial of Targeted Therapeutics: Liposomal Glutathione and Curcumin

DTIC Science & Technology

2016-10-01

Syndrome, P. Goodnik and N.G. Klimas, eds., American Psychiatric Press, Washington, D.C., 1993. 4 2. Clinical Management of Chronic...Klimas, N. and Fletcher, M.A. Stress Management Interventions and psychosocial predictors of progression in HIV-1 infection. in K.Goodkin, ed...Fletcher, M.A. Psychoimmunology and Stress Management in HIV-1 Infection. in Update in Psychoneuroimmunology, Gorman, J.M. and Kertzner, R.M., eds

An update on the role of daratumumab in the treatment of multiple myeloma

PubMed Central

Costello, Caitlin

2016-01-01

Monoclonal antibodies (mAbs) have emerged as a promising new drug class for the treatment of multiple myeloma (MM). Daratumumab (DARA), a CD38 mAb, has demonstrated safety, tolerability and activity in a range of clinical trials, both as monotherapy and in combination strategies for MM. The favorable efficacy results in heavily pretreated patients with advanced MM have provided the rationale for the investigation of DARA in a number of ongoing and future phase II and III trials. The general tolerability of mAbs has allowed for widespread investigation and use of DARA among a variety of MM patients, however their use requires special consideration. Infusion-related reactions (IRRs), interference with blood compatibility assays and response assessments are all unique factors related to the use of DARA. This review provides an update of the results from the DARA clinical trials conducted to date, its future plans for investigation, and practical management considerations for the use of DARA in daily practice. PMID:28042457

Update on extranodal lymphomas. Conclusions of the Workshop held by the EAHP and the SH in Thessaloniki, Greece

PubMed Central

Campo, E; Chott, A; Kinney, MC; Leoncini, L; Meijer, CJLM; Papadimitriou, CS; Piris, MA; Stein, H; Swerdlow, SH

2006-01-01

Campo E, Chott A, Kinney M C, Leoncini L, Meijer C J L M, Papadimitriou C S, Piris M A, Stein H & Swerdlow S H (2006) Histopathology48, 481–504 Update on extranodal lymphomas. Conclusions of the Workshop held by the EAHP and the SH in Thessaloniki, Greece Classification and proper treatment of extranodal lymphoma is hindered by the diversity of lymphoma types and the relative rarity of many of these tumour types. In order to review controversial issues in extranodal lymphoma diagnosis, a joint Workshop of the European Haematopathology Association (EAHP) and the Society for Hematopathology (SH) was held, where 99 selected cases were reviewed and discussed. This Workshop summary is focused on the most controversial aspect of cutaneous B-cell lymphoma, other extranodal B-cell lymphomas, plasmablastic lymphoma and anaplastic large-cell lymphoma in extranodal sites, and makes practical recommendations about diagnosis and therapeutic approaches. PMID:16623775

Muscle function loss

MedlinePlus

... ed. Philadelphia, PA: Elsevier Mosby; 2013:chap 35. Review Date 2/27/2016 Updated by: Amit M. ... Clinical Neurology, SUNY Stony Brook, School of Medicine. Review provided by VeriMed Healthcare Network. Also reviewed by ...

Intracranial pressure monitoring

MedlinePlus

... 22720148 www.ncbi.nlm.nih.gov/pubmed/22720148 . Review Date 5/15/2017 Updated by: Amit M. ... Stony Brook, School of Medicine, Stony Brook, NY. Review provided by VeriMed Healthcare Network. Also reviewed by ...

Obsessive-compulsive personality disorder

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Managing your depression - teens

MedlinePlus

... Updated by: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

Theory-of-mind in individuals with Alström syndrome is related to executive functions, and verbal ability.

PubMed

Frölander, Hans-Erik; Möller, Claes; Rudner, Mary; Mishra, Sushmit; Marshall, Jan D; Piacentini, Heather; Lyxell, Björn

2015-01-01

This study focuses on cognitive prerequisites for the development of theory-of-mind (ToM), the ability to impute mental states to self and others in young adults with Alström syndrome (AS). AS is a rare and quite recently described recessively inherited ciliopathic disorder which causes progressive sensorineural hearing loss and juvenile blindness, as well as many other organ dysfunctions. Two cognitive abilities were considered; Phonological working memory (WM) and executive functions (EF), both of importance in speech development. Ten individuals (18-37 years) diagnosed with AS, and 20 individuals with no known impairment matched for age, gender, and educational level participated. Sensory functions were measured. Information about motor functions and communicative skills was obtained from responses to a questionnaire. ToM was assessed using Happés strange stories, verbal ability by a vocabulary test, phonological WM by means of an auditory presented non-word serial recall task and EF by tests of updating and inhibition. The AS group performed at a significantly lower level than the control group in both the ToM task and the EF tasks. A significant correlation was observed between recall of non-words and EF in the AS group. Updating, but not inhibition, correlated significantly with verbal ability, whereas both updating and inhibition were significantly related to the ability to initiate and sustain communication. Poorer performance in the ToM and EF tasks were related to language perseverance and motor mannerisms. The AS group displayed a delayed ToM as well as reduced phonological WM, EF, and verbal ability. A significant association between ToM and EF, suggests a compensatory role of EF. This association may reflect the importance of EF to perceive and process input from the social environment when the social interaction is challenged by dual sensory loss. We argue that limitations in EF capacity in individuals with AS, to some extent, may be related to early blindness and progressive hearing loss, but maybe also to gene specific abnormalities.

Theory-of-mind in individuals with Alström syndrome is related to executive functions, and verbal ability

PubMed Central

Frölander, Hans-Erik; Möller, Claes; Rudner, Mary; Mishra, Sushmit; Marshall, Jan D.; Piacentini, Heather; Lyxell, Björn

2015-01-01

Objective: This study focuses on cognitive prerequisites for the development of theory-of-mind (ToM), the ability to impute mental states to self and others in young adults with Alström syndrome (AS). AS is a rare and quite recently described recessively inherited ciliopathic disorder which causes progressive sensorineural hearing loss and juvenile blindness, as well as many other organ dysfunctions. Two cognitive abilities were considered; Phonological working memory (WM) and executive functions (EF), both of importance in speech development. Methods: Ten individuals (18–37 years) diagnosed with AS, and 20 individuals with no known impairment matched for age, gender, and educational level participated. Sensory functions were measured. Information about motor functions and communicative skills was obtained from responses to a questionnaire. ToM was assessed using Happés strange stories, verbal ability by a vocabulary test, phonological WM by means of an auditory presented non-word serial recall task and EF by tests of updating and inhibition. Results: The AS group performed at a significantly lower level than the control group in both the ToM task and the EF tasks. A significant correlation was observed between recall of non-words and EF in the AS group. Updating, but not inhibition, correlated significantly with verbal ability, whereas both updating and inhibition were significantly related to the ability to initiate and sustain communication. Poorer performance in the ToM and EF tasks were related to language perseverance and motor mannerisms. Conclusion: The AS group displayed a delayed ToM as well as reduced phonological WM, EF, and verbal ability. A significant association between ToM and EF, suggests a compensatory role of EF. This association may reflect the importance of EF to perceive and process input from the social environment when the social interaction is challenged by dual sensory loss. We argue that limitations in EF capacity in individuals with AS, to some extent, may be related to early blindness and progressive hearing loss, but maybe also to gene specific abnormalities. PMID:26441796

Update on optical design of adaptive optics system at Lick Observatory

NASA Astrophysics Data System (ADS)

Bauman, Brian J.; Gavel, Donald T.; Waltjen, Kenneth E.; Freeze, Gary J.; Hurd, Randall L.; Gates, Elinor L.; Max, Claire E.; Olivier, Scot S.; Pennington, Deanna M.

2002-02-01

In 1999, we presented our plan to upgrade the adaptive optics (AO) system on the Lick Observatory Shane telescope (3m) from a prototype instrument pressed into field service to a facility instrument. This paper updates the progress of that plan and details several important improvements in the alignment and calibration of the AO bench. The paper also includes a discussion of the problems seen in the original design of the tip/tilt (t/t) sensor used in laser guide star mode, and how these problems were corrected with excellent results.

Update on Optical Design of Adaptive Optics System at Lick Observatory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bauman, B J; Gavel, D T; Waltjen, K E

2001-07-31

In 1999, we presented our plan to upgrade the adaptive optics (AO) system on the Lick Observatory Shane telescope (3m) from a prototype instrument pressed into field service to a facility instrument. This paper updates the progress of that plan and details several important improvements in the alignment and calibration of the AO bench. The paper also includes a discussion of the problems seen in the original design of the tip/tilt (t/t) sensor used in laser guide star mode, and how these problems were corrected with excellent results.

77 FR 19657 - Combined Notice of Filings #2

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-02

.... Applicants: Wolverine Power Supply Cooperative, Inc. Description: Amended Market Power Update of Wolverine Power Supply Cooperative, Inc. Filed Date: 3/9/12. Accession Number: 20120309-5160. Comments Due: 5 p.m...

Genetics Home Reference: Gaucher disease

MedlinePlus

... Campbell PE, Charrow J, Cohen IJ, Harris CM, Kaplan P, Mengel E, Pocovi M, Vellodi A. Pediatric ... Updated Pages Reviewed : September 2014 Published : June 19, 2018 The resources on this site should not be ...

Meclofenamate overdose

MedlinePlus

... RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 9th ed. Philadelphia, PA: ... 2017 Updated by: Jacob L. Heller, MD, MHA, Emergency Medicine, Emeritus, Virginia Mason Medical Center, Seattle, WA. Also ...

Ketoprofen overdose

MedlinePlus

... RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 9th ed. Philadelphia, PA: ... 2017 Updated by: Jacob L. Heller, MD, MHA, Emergency Medicine, Emeritus, Virginia Mason Medical Center, Seattle, WA. Also ...

Hydroxyzine overdose

MedlinePlus

... RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 9th ed. Philadelphia, PA: ... 2017 Updated by: Jacob L. Heller, MD, MHA, Emergency Medicine, Emeritus, Virginia Mason Medical Center, Seattle, WA. Also ...

Imaging of Prominent Carbon Stars: From CRIRES and NACO to MATISSE

NASA Astrophysics Data System (ADS)

Hron, Josef

2018-04-01

We present an update to the spectro-astrometry carried out with CRIRES for some prominent carbon stars in the L- and M-bands. For TX Psc additional NACO imaging is compared with the CRIRES results. We also discuss the prospects and plans for MATISSE, the second generation VLTI instrument to operate in L, M and N.

A Development of Learning Widget on M-Learning and E-Learning Environments

ERIC Educational Resources Information Center

Kim, SooHwan; Kim, HyeonCheol; Han, SeonKwan

2013-01-01

This article describes the development of learning widget on m-learning and e-learning environments. A widget is a small, simple and useful application supporting user-oriented contents. The user may select and install widgets that are convenient as well as an auto-updating application including weather or calendar. These widgets are especially…

77 FR 14828 - Notice of Public Meeting for the National Park Service (NPS) Alaska Region's Subsistence Resource...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-13

... the meeting will start at 9 a.m. and conclude at 5 p.m. or until business is completed. For Further... Other Agency Comments. 8. Old Business. a. Subsistence Collections and Uses of Shed or Discarded Animal & Plants Environmental Assessment Update. b. SRC Recommendations. 9. New Business. 10. Federal Subsistence...

75 FR 35446 - Environmental Management Site-Specific Advisory Board, Northern New Mexico

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-22

... Period. 1:30 p.m. Old Business. Written reports. Update on Fall EM SSAB Chairs' Meeting (Hosted by NNMCAB). Other items. 1:45 p.m. New Business. EM SSAB Chairs' Recommendation on Baseline Funding Support, Ralph... listed above. Written statements may be filed with the Board either before or after the meeting...

75 FR 55603 - Meeting of the California Desert District Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-13

..., October 2, 2010, from 8 a.m. to 4:30 p.m. at the BLM Needles Field Office, 1303 S Highway 95, Needles, CA 92363. Agenda topics will include updates by Council members and reports from the BLM District Manager and five field office managers. Final agenda items, including details of the field tour, will be...

78 FR 70318 - Meeting of the California Desert District Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-25

... an open work planning meeting on Friday, December 6, 2013 from 9 a.m. to 4 p.m. No field trip is... include updates by council members, the BLM California Desert District manager, five field office managers.... SUPPLEMENTARY INFORMATION: All DAC meetings are open to the public. Public comment for items not on the agenda...

75 FR 61768 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-06

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: October 28, 2010, 9 a.m. to 5 p.m. EDT. Place... meeting will include, but are not limited to: Updates from the Division of Vaccine Injury Compensation...

76 FR 27651 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-12

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: June 9, 2011, 1 p.m. to 5 p.m. EDT; June 10, 2011, 9... will include, but are not limited to: updates from the Division of Vaccine Injury Compensation (DVIC...

75 FR 27797 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-18

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: June 10, 2010, 1 p.m. to 5:30 p.m. EDT; June 11, 2010... meeting will include, but are not limited to: updates from the Division of Vaccine Injury Compensation...

77 FR 31624 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-29

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: June 14, 2012, 8:30 a.m. to 11:45 a.m. EDT. Place... will include, but are not limited to: updates from the Division of Vaccine Injury Compensation (DVIC...

76 FR 45583 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-29

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: September 1, 2011, 1 p.m. to 5 p.m. EDT, September 2... September meeting will include, but are not limited to: updates from the Division of Vaccine Injury...

78 FR 14311 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: March 07, 2013, 10:00 a.m. to 4:00 p.m. EDT. Place... for the March meeting will include, but are not limited to: Updates from the Division of Vaccine...

75 FR 46952 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-04

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: September 2, 2010, 1 p.m. to 5:30 p.m. EDT. September... for the September meeting will include, but are not limited to: updates from the Division of Vaccine...

77 FR 52041 - Advisory Commission on Childhood Vaccines, Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-28

... Commission on Childhood Vaccines, Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date and Time: September 06, 2012, 1:00 p.m. to 5:15 p.m. EDT. Place... September meeting will include, but are not limited to: Updates from the Division of Vaccine Injury...

76 FR 9030 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-16

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Date And Time: March 3, 2011, 9 a.m. to 5 p.m. EDT, March 4, 2011, 9... will include, but are not limited to: updates from the Division of Vaccine Injury Compensation (DVIC...

77 FR 10756 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV). Dates and Times: March 8, 2012, 9 a.m. to 5 p.m. EST. March 9, 2012... will include, but are not limited to: Updates from the Division of Vaccine Injury Compensation (DVIC...

75 FR 8727 - Advisory Commission on Childhood Vaccines; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-25

... Commission on Childhood Vaccines; Notice of Meeting In accordance with section 10(a)(2) of the Federal... Commission on Childhood Vaccines (ACCV) Date and Time: March 4, 2010, 1 p.m. to 5:30 p.m. EST. March 5, 2010... will include, but are not limited to: Updates from the Division of Vaccine Injury Compensation (DVIC...

The Smart Mine Simulator User’s Guide and Algorithm Description

DTIC Science & Technology

1993-12-01

meters control kill range tank 2 meters * APC 1.5 meters other ground 1 meter munition burst type projectile 105APDS detonator M739 155mm C-1 WAM...in range 15 meters munition launch burst type projectile TOW detonator M739 155mm WAM Sublet: component parameter Index value sublet regular update...detonator M739 155mm sensor detection range 50 meters control firing angle -55 degrees munition fire burst type projectile TOW detonator M739 155mm

Development status of the mid-infrared two-field camera and spectrograph MIMIZUKU for the TAO 6.5-m Telescope

NASA Astrophysics Data System (ADS)

Kamizuka, Takafumi; Miyata, Takashi; Sako, Shigeyuki; Ohsawa, Ryou; Okada, Kazushi; Uchiyama, Masahito S.; Mori, Kiyoshi; Yamaguchi, Jumpei; Asano, Kentaro; Uchiyama, Mizuho; Sakon, Itsuki; Onaka, Takashi; Kataza, Hirokazu; Hasegawa, Sunao; Usui, Fumihiko; Takato, Naruhisa; Aoki, Tsutomu; Doi, Mamoru; Kato, Natsuko M.; Kitagawa, Yutaro; Kobayakawa, Yutaka; Kohno, Kotaro; Konishi, Masahiro; Minezaki, Takeo; Morokuma, Tomoki; Motohara, Kentaro; Ohashi, Hirofumi; Soyano, Takao; Takahashi, Hidenori; Tamura, Yoichi; Tanabé, Toshihiko; Tanaka, Masuo; Tarusawa, Ken'ichi; Terao, Yasunori; Yoshii, Yuzuru

2016-08-01

MIMIZUKU is the first-generation mid-infrared instrument for the university of Tokyo Atacama Observatory (TAO) 6.5-m telescope. MIMIZUKU provides imaging and spectroscopic monitoring capabilities in a wide wavelength range from 2 to 38 μm, including unique bands like 2.7-μm and 30-μm band. Recently, we decided to add spectroscopic functions, KL-band mode (λ= 2.1-4.0 μm R =λ/Δλ 210) and 2.7-μm band mode ( λ= 2.4-2.95 μm R 620), and continuous spectroscopic coverage from 2.1 to 26 μm is realized by this update. Their optical designing is completed, and fabrications of optical elements are ongoing. As recent progress, we also report the completion of the cryogenic system and optics. The cryogenic system has been updated by changing materials and structures of thermal links, and the temperatures of the optical bench and detector mounting stages finally achieved required temperatures. Their stability against instrument attitude is also confirmed through an inclination test. As for the optics, its gold-plated mirrors have been recovered from galvanic corrosion by refabrication and reconstruction. Enough image quality and stability are confirmed by room-temperature tests. MIMIZUKU is intended to be completed in this autumn, and commissioning at the Subaru telescope and scientific operations on the TAO telescope are planned in 2017 and around 2019, respectively. In this paper, these development activities and future prospects of MIMIZUKU are reported.

76 FR 39862 - Combined Notice of Filings #1

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-07

...: ER10-3260-002. Applicants: Granite Ridge Energy, LLC. Description: Updated Market Power Analysis of Granite Ridge Energy, LLC. Filed Date: 06/28/2011. Accession Number: 20110628-5188. Comment Date: 5 p.m...

Common peroneal nerve dysfunction

MedlinePlus

... Silver JK, Rizzo TD Jr, eds. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation . 3rd ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 75. Review Date 8/7/2017 Updated by: Amit M. ...

Genetics Home Reference: mucopolysaccharidosis type I

MedlinePlus

... Arn P, Beck M, Clarke JT, Guffon N, Kaplan P, Muenzer J, Norato DY, Shapiro E, Thomas ... Updated Pages Reviewed : December 2012 Published : June 19, 2018 The resources on this site should not be ...

Genetics Home Reference: Alström syndrome

MedlinePlus

... Hoffman JD, Jacobson Z, Young TL, Marshall JD, Kaplan P. Familial variable expression of dilated cardiomyopathy in ... Updated Pages Reviewed : September 2014 Published : June 19, 2018 The resources on this site should not be ...

Prostate brachytherapy - discharge

MedlinePlus

... chap 84. Read More Prostate brachytherapy Prostate cancer Prostate-specific antigen (PSA) blood test Radical prostatectomy Review Date 2/21/2017 Updated by: Jennifer Sobol, DO, Urologist with the Michigan ... Cancer Browse the Encyclopedia A.D.A.M., ...

Exercises to help prevent falls

MedlinePlus

... A.D.A.M. Editorial team. Related MedlinePlus Health Topics Exercise and Physical Fitness Falls Browse the Encyclopedia A. ... of Health and Human Services National Institutes of Health Page last updated: 04 June 2018

Oral hypoglycemics overdose

MedlinePlus

... M. Hypoglycemic agent overdose. In: Adams JG, ed. Emergency Medicine: Clinical Essentials . 2nd ed. Philadelphia, PA: Elsevier Saunders; ... 2017 Updated by: Jacob L. Heller, MD, MHA, Emergency Medicine, Emeritus, Virginia Mason Medical Center, Seattle, WA. Also ...

Amitriptyline hydrochloride overdose

MedlinePlus

... RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice . 9th ed. Philadelphia, PA: ... 2017 Updated by: Jacob L. Heller, MD, MHA, Emergency Medicine, Emeritus, Virginia Mason Medical Center, Seattle, WA. Also ...

Update of potency factors for asbestos-related lung cancer and mesothelioma.

PubMed

Berman, D Wayne; Crump, Kenny S

2008-01-01

The most recent update of the U.S. Environmental Protection Agency (EPA) health assessment document for asbestos (Nicholson, 1986, referred to as "the EPA 1986 update") is now 20 years old. That document contains estimates of "potency factors" for asbestos in causing lung cancer (K(L)'s) and mesothelioma (K(M)'s) derived by fitting mathematical models to data from studies of occupational cohorts. The present paper provides a parallel analysis that incorporates data from studies published since the EPA 1986 update. The EPA lung cancer model assumes that the relative risk varies linearly with cumulative exposure lagged 10 years. This implies that the relative risk remains constant after 10 years from last exposure. The EPA mesothelioma model predicts that the mortality rate from mesothelioma increases linearly with the intensity of exposure and, for a given intensity, increases indefinitely after exposure ceases, approximately as the square of time since first exposure lagged 10 years. These assumptions were evaluated using raw data from cohorts where exposures were principally to chrysotile (South Carolina textile workers, Hein et al., 2007; mesothelioma only data from Quebec miners and millers, Liddell et al., 1997) and crocidolite (Wittenoom Gorge, Australia miners and millers, Berry et al., 2004) and using published data from a cohort exposed to amosite (Paterson, NJ, insulation manufacturers, Seidman et al., 1986). Although the linear EPA model generally provided a good description of exposure response for lung cancer, in some cases it did so only by estimating a large background risk relative to the comparison population. Some of these relative risks seem too large to be due to differences in smoking rates and are probably due at least in part to errors in exposure estimates. There was some equivocal evidence that the relative risk decreased with increasing time since last exposure in the Wittenoom cohort, but none either in the South Carolina cohort up to 50 years from last exposure or in the New Jersey cohort up to 35 years from last exposure. The mesothelioma model provided good descriptions of the observed patterns of mortality after exposure ends, with no evidence that risk increases with long times since last exposure at rates that vary from that predicted by the model (i.e., with the square of time). In particular, the model adequately described the mortality rate in Quebec chrysotile miners and millers up through >50 years from last exposure. There was statistically significant evidence in both the Wittenoom and Quebec cohorts that the exposure intensity-response is supralinear(1) rather than linear. The best-fitting models predicted that the mortality rate varies as [intensity](0.47) for Wittenoom and as [intensity](0.19) for Quebec and, in both cases, the exponent was significantly less than 1 (p< .0001). Using the EPA models, K(L)'s and K(M)'s were estimated from the three sets of raw data and also from published data covering a broader range of environments than those originally addressed in the EPA 1986 update. Uncertainty in these estimates was quantified using "uncertainty bounds" that reflect both statistical and nonstatistical uncertainties. Lung cancer potency factors (K(L)'s) were developed from 20 studies from 18 locations, compared to 13 locations covered in the EPA 1986 update. Mesothelioma potency factors (K(M)'s) were developed for 12 locations compared to four locations in the EPA 1986 update. Although the 4 locations used to calculate K(M) in the EPA 1986 update include one location with exposures to amosite and three with exposures to mixed fiber types, the 14 K(M)'s derived in the present analysis also include 6 locations in which exposures were predominantly to chrysotile and 1 where exposures were only to crocidolite. The K(M)'s showed evidence of a trend, with lowest K(M)'s obtained from cohorts exposed predominantly to chrysotile and highest K(M)'s from cohorts exposed only to amphibole asbestos, with K(M)'s from cohorts exposed to mixed fiber types being intermediate between the K(M)'s obtained from chrysotile and amphibole environments. Despite the considerable uncertainty in the K(M) estimates, the K(M) from the Quebec mines and mills was clearly smaller than those from several cohorts exposed to amphibole asbestos or a mixture of amphibole asbestos and chrysotile. For lung cancer, although there is some evidence of larger K(L)'s from amphibole asbestos exposure, there is a good deal of dispersion in the data, and one of the largest K(L)'s is from the South Carolina textile mill where exposures were almost exclusively to chrysotile. This K(L) is clearly inconsistent with the K(L) obtained from the cohort of Quebec chrysotile miners and millers. The K(L)'s and K(M)'s derived herein are defined in terms of concentrations of airborne fibers measured by phase-contrast microscopy (PCM), which only counts all structures longer than 5 microm, thicker than about 0.25 microm, and with an aspect ratio > or =3:1. Moreover, PCM does not distinguish between asbestos and nonasbestos particles. One possible reason for the discrepancies between the K(L)'s and K(M)'s from different studies is that the category of structures included in PCM counts does not correspond closely to biological activity. In the accompanying article (Berman and Crump, 2008) the K(L)'s and K(M)'s and related uncertainty bounds obtained in this article are paired with fiber size distributions from the literature obtained using transmission electron microscopy (TEM). The resulting database is used to define K(L)'s and K(M)'s that depend on both the size (e.g., length and width) and mineralogical type (e.g., chrysotile or crocidolite) of an asbestos structure. An analysis is conducted to determine how well different K(L) and K(M) definitions are able to reconcile the discrepancies observed herein among values obtained from different environments.

[Interpretation of the updates of NCCN 2017 version 1.0 guideline for colorectal cancer].

PubMed

Chen, Gong

2017-01-25

The NCCN has recently released its 2017 version 1.0 guideline for colorectal cancer. There are several updates from this new version guideline which are believed to change the current clinical practice. Update one, low-dose aspirin is recommended for patients with colorectal cancer after colectomy for secondary chemoprevention. Update two, biological agents are removed from the neoadjuvant treatment regimen for resectable metastatic colorectal cancer (mCRC). This update is based on lack of evidence to support benefits of biological agents including bevacizumab and cetuximab in the neoadjuvant setting. Both technical criteria and prognostic information should be considered for decision-making. Currently biological agents may not be excluded from the neoadjuvant setting for patients with resectable but poor prognostic disease. Update three, panitumumab and cetuximab combination therapy is only recommended for left-sided tumors in the first line therapy. The location of the primary tumor can be both prognostic and predictive in response to EGFR inhibitors in metastatic colorectal cancer. Cetuximab and panitumumab confer little benefit to patients with metastatic colorectal cancer in the primary tumor originated on the right side. On the other hand, EGFR inhibitors provide significant benefit compared with bevacizumab-containing therapy or chemotherapy alone for patients with left primary tumor. Update four, PD-1 immune checkpoint inhibitors including pembrolizumab or nivolumab are recommended as treatment options in patients with metastatic deficient mismatch repair (dMMR) colorectal cancer in second- or third-line therapy. dMMR tumors contain thousands of mutations, which can encode mutant proteins with the potential to be recognized and targeted by the immune system. It has therefore been hypothesized that dMMR tumors may be sensitive to PD-1 inhibitors.

77 FR 5004 - Combined Notice of Filings #1

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

.... Applicants: Granite Ridge Energy, LLC. Description: Additional Supplement to Updated Market Power Analysis of Granite Ridge Energy, LLC. Filed Date: 1/23/12. Accession Number: 20120123-5303. Comments Due: 5 p.m. ET 2...

Conjunctivitis

MedlinePlus

... 22. Review Date 8/20/2016 Updated by: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Pinkeye Read more NIH ...

Genetics Home Reference: hypomagnesemia with secondary hypocalcemia

MedlinePlus

... Pelken L, Lotan D, Syrrou M, Prebble JJ, Cole DE, Metzger DL, Rahman S, Tajima T, Shu SG, ... medicine? What is newborn screening? New Pages Lyme disease Fibromyalgia White-Sutton syndrome All New & Updated Pages ...

Pregnancy After Gastric Bypass: Is It Safe?

MedlinePlus

... M.D. Ouyang DW. Fertility and pregnancy after bariatric surgery. https://www.update.com/contents/search. Accessed April ... 3, 2018. Carreau AM, et al. Pregnancy after bariatric surgery: Balancing risks and benefits. Canadian Journal of Diabetes. ...

Nystagmus

MedlinePlus

... ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 919. Review Date 2/23/2017 Updated by: Amit M. Shelat, DO, FACP, Attending Neurologist and Assistant Professor of Clinical Neurology, SUNY Stony ... NY. Review provided by VeriMed Healthcare Network. Also reviewed by ...

What Is a Coronary Artery Spasm?

MedlinePlus

... by quitting smoking and controlling high cholesterol and high blood pressure. With Rekha Mankad, M.D. Hung MJ, et al. Coronary artery spasm: Review and update. International Journal of Medical Sciences. 2014;11:1161. Bonow RO, ...

Management of Mucosal Basal Cell Carcinoma of the Lip: An Update and Comprehensive Review of the Literature.

PubMed

Loh, Tiffany; Rubin, Ashley G; Brian Jiang, Shang I

2016-12-01

Basal cell carcinoma (BCC) is the most common malignancy in the United States. Most BCCs occur on cutaneous surfaces, but rare cases on the mucosal lip have also been documented. Because only a small number of mucosal BCC (mBCC) cases have been reported, data on their clinical characteristics and management are limited. To perform an updated literature review of the management of mBCCs on the lip. A comprehensive literature review was conducted through a search of the PubMed database with the key phrases "mucosal basal cell carcinoma," "basal cell carcinoma mucosa," and "basal cell carcinoma lip mucosa." Forty-eight cases of mBCCs have been reported, and 35 had sufficient data for analysis. The average age at presentation was 66.8 years, and 57% (n = 20) had a history of skin cancer. Most cases were treated with surgical excision or Mohs micrographic surgery (MMS), with only 1 recurrence in the literature. Furthermore, the authors present 8 additional cases of mBCCs successfully treated with MMS. Mucosal basal cell carcinomas are rare, and skin cancer history may be a risk factor. Because the lip is a cosmetically and functionally important area, MMS may be the preferred treatment method for mBCCs in this location.

Pathways of spread of Phytophthora ramorum in a simulated nursery setting: an update

Treesearch

Kurt Heungens; Bjorn Gehesqui& egrave; re; Kris Van Poucke; Annelies Vercauteren; Martine Maes

2013-01-01

European phytosanitary measures as applied to nurseries require that potential host plants within a radius of 2 m of a Phytophthora ramorum-infected plant must be destroyed and that remaining host plants within a radius of 10 m cannot be traded until they are inspected and found to be pest free at further specific inspections. Despite the wide...

76 FR 60582 - Notice of Meeting of the Industry Trade Advisory Committee on Small and Minority Business (ITAC-11)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

... Finance Update. --Trans-Atlantic Business Dialogue Activities. --U.S. Commercial Service National Export... Committee on Small and Minority Business (ITAC-11) AGENCY: Office of the United States Trade Representative... Business (ITAC-11) will hold a meeting on Wednesday, October 12, 2011, from 9 a.m. to 4 p.m. The meeting...

77 FR 47858 - Office of The Director, National Institutes of Health; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-10

...) and 552b(c)(9)(B), Title 5 U.S.C., as amended. The closed portion of the meeting is likely to include... Research Training Opportunities and Update on Working Group on Chimpanzees in NIH-Supported Research. Place...: 1:35 p.m. to 3:15 p.m. Agenda: Research Projects Involving Chimpanzees and Second-Level Review of...

USING IN VIVO GAS UPDATE STUDIES TO ESTIMATE METABOLIC RATE CONSTANTS FOR CCL CHEMICALS: 1,1-DICHLOROPROPANE AND 2,2-DICHLOROPROPANE

EPA Science Inventory

USING IN VIVO GAS UPTAKE STUDIES TO ESTIMATE METABOLIC RATE CONSTANTS FOR CCL CHEMICALS: 1,1-DICHLOROPROPENE AND 2,2-DICHLOROPROPANE.
Mitchell, C T, Evans, M V, Kenyon, E M. NHEERL, U.S. EPA, ORD, ETD, RTP, NC

The Safe Drinking Water Act Amendments of 1996 required ...

78 FR 9730 - Boston Harbor Islands Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

.... The agenda includes a presentation by Sally Snowman, 70th keeper of Boston Light, the election of officers, and a park update. Date/Time: March 6, 2013, 6:00 p.m. to 8:00 p.m. (Eastern). Location: Wilmer... information--may be made publicly available at any time. While you can ask us in your comment to withhold your...

Assessment and Rehabilitation of Central Sensory Impairments for Balance in mTBI

DTIC Science & Technology

2016-10-01

place; 95% complete. ● Purchasing and testing software of Opals ; awaiting release of newer, updated sensor from APDM to determine need for more sensors...2016. ● Develop new algorithm to automatically quantify head movements from Opal sensor; 100% complete 23-Sep-2016. ● Set up and test gait paradigm...Interaction in Balance (mCTSIB), Modified Balance Error Scoring System (mBESS) and walking tests, subjects wear five Opal inertial sensors (APDM, Inc

Runtime Support for Type-Safe Dynamic Java Classes

DTIC Science & Technology

2000-01-01

Section 4.3. For each dynamic class C, we create a proxy class, Cproxy, and an implementation class, Cimp . In order to wrap method calls, Cproxy...wrapper method (W) and a reference to the associated method body (M). W explicitly invokes M, which points to the corresponding method body in Cimp ...When C’s implementation Cimp is switched, M is updated to point to the corresponding method object in the new C imp. Cproxy also contains a reference

Light Nonaqueous-Phase Liquid Weathering at Various Fuel Release Sites, 2003 Update

DTIC Science & Technology

2003-08-01

the survival of most soil microbes; and • Requirements for microbial proliferation (e.g., nutrients, terminal electron acceptors, pH, moisture...P.D. Boehm, M. Marchand, R.M. Atlas , D.M. Ward, and D.A. Wolfe. 1993. The Fate of Amoco Cadiz Oil. Science, Vol. 221, pp 122-129. Groundwater...Migration of Organic Fluids Immiscible. Pollutants in Porous Media, Ecological Studies. Vol 47, pp. 27-48. Springer-Verlag. New York. Seagren, E

Low-Level Turbulence Forecasts From Fine-Scale Models

DTIC Science & Technology

2014-02-01

aircraft which often fly above 6097 m for much of the flight. Sharman et al. (35) have developed the Graphical Turbulence Guidance ( GTG ), which is a...original GTG was used above 6097-m AGL and is for MOD or greater CAT. The Rapid Refresh Model, which is an hourly updated assimilation model operational...applications and tactical decision aids. The recent version of GTG (V2.5) forecasts turbulence as low as 3354 m. Silberberg (36) notes that the Aviation

ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments

PubMed Central

Chèneby, Jeanne; Gheorghe, Marius; Artufel, Marie

2018-01-01

Abstract With this latest release of ReMap (http://remap.cisreg.eu), we present a unique collection of regulatory regions in human, as a result of a large-scale integrative analysis of ChIP-seq experiments for hundreds of transcriptional regulators (TRs) such as transcription factors, transcriptional co-activators and chromatin regulators. In 2015, we introduced the ReMap database to capture the genome regulatory space by integrating public ChIP-seq datasets, covering 237 TRs across 13 million (M) peaks. In this release, we have extended this catalog to constitute a unique collection of regulatory regions. Specifically, we have collected, analyzed and retained after quality control a total of 2829 ChIP-seq datasets available from public sources, covering a total of 485 TRs with a catalog of 80M peaks. Additionally, the updated database includes new search features for TR names as well as aliases, including cell line names and the ability to navigate the data directly within genome browsers via public track hubs. Finally, full access to this catalog is available online together with a TR binding enrichment analysis tool. ReMap 2018 provides a significant update of the ReMap database, providing an in depth view of the complexity of the regulatory landscape in human. PMID:29126285

M4FT-15OR03100415 - Update on COF-based Adsorbent Survey

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayes, Richard T.; Dai, Sheng

2015-02-01

This letter report provides an update on activities focused on generating nanoporous adsorbents involving covalent organic frameworks (COF) and zeolitic imidazolium frameworks (ZIF). The adsorbents have been generated and screened in a uranyl-spiked brine (6 ppm U) to understand uranyl-binding behavior. Porous organic polymers (POP) also qualify under this title and are similar to the COF PPN-6 that is discussed herein. Seven COF/POP and one 1 ZIF were synthesized and screened for uranyl adsorption. Seawater screening is on-going via batch testing while flow screening systems are being developed at PNNL.

Water-clover ferns, Marsilea, in the Southeastern United States

USGS Publications Warehouse

Jacono, Colette C.; Johnson, David M.

2006-01-01

A surge in the collection of exotic Marsilea, M. mutica, M. minuta and M. hirsuta in the southeastern United States has prompted the need for updated identification aids. This study provides an annotated key to all water-clover ferns occurring in the region. It describes and illustrates recently documented exotic species and a previously misidentified western introduction. It details the rediscovery of M. ancylopoda, presumed extinct, and confirms its identification as the western species M. oligospora. Finally it clarifies the status and distribution of two additional western North American species introduced to the southeast, M. vestita and M. macropoda.

Eyelid bump

MedlinePlus

... 423. Review Date 8/20/2016 Updated by: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Eyelid Disorders Read more ...

77 FR 22800 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-17

... meetings, topics will include: North and South Dakota Field Office manager updates, briefings by council.... M. Elaine Raper, Dakotas District Manager, Eastern Montana. [FR Doc. 2012-9207 Filed 4-16-12; 8:45...

Movement - unpredictable or jerky

MedlinePlus

... ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 410. Review Date 2/23/2017 Updated by: Amit M. Shelat, DO, FACP, Attending Neurologist and Assistant Professor of Clinical Neurology, SUNY Stony ... NY. Review provided by VeriMed Healthcare Network. Also reviewed by ...

Updated Reliability Evaluation of V730 Transmission

DOT National Transportation Integrated Search

1983-11-01

This report culminates a two-year review of factors concerning the reliability of the Detroit Diesel Allison V730 automatic three-speed transmission for urban transit buses. This report is a continuing examination of the transmission's reliability. M...

Correction: Update on VTE.

PubMed

Bartholomew, John R

2018-03-01

In the article, "Update on the management of venous thromboembolism" (Bartholomew JR, Cleve Clin J Med 2017; 84[suppl 3]:39-46), 2 sentences in the text regarding dose reduction for body weight have errors. The corrected sentences follow: On page 42, left column, the last 5 lines should read: "The recommended dose should be reduced to 2.5 mg twice daily in patients that meet 2 of the following criteria: age 80 or older; body weight of 60 kg or less; or with a serum creatinine 1.5 mg/dL or greater." And on page 42, right column, the sentence 10 lines from the top should read: "Edoxaban is given orally at 60 mg once daily but reduced to 30 mg once daily if the CrCL is 30 mL/min to 50 mL/min, if body weight is 60 kg or less, or with use of certain P-glycoprotein inhibitors."

a Model for Brand Competition Within a Social Network

NASA Astrophysics Data System (ADS)

Huerta-Quintanilla, R.; Canto-Lugo, E.; Rodríguez-Achach, M.

An agent-based model was built representing an economic environment in which m brands are competing for a product market. These agents represent companies that interact within a social network in which a certain agent persuades others to update or shift their brands; the brands of the products they are using. Decision rules were established that caused each agent to react according to the economic benefits it would receive; they updated/shifted only if it was beneficial. Each agent can have only one of the m possible brands, and she can interact with its two nearest neighbors and another set of agents which are chosen according to a particular set of rules in the network topology. An absorbing state was always reached in which a single brand monopolized the network (known as condensation). The condensation time varied as a function of model parameters is studied including an analysis of brand competition using different networks.

The Galactic O-Star Catalog (GOSC) and the Galactic O-Star Spectroscopic Survey (GOSSS): current status

NASA Astrophysics Data System (ADS)

Maíz Apellániz, J.; Alonso Moragón, A.; Ortiz de Zárate Alcarazo, L.; The Gosss Team

2017-03-01

We present the updates of the Galactic O-Star Catalog (GOSC) that we have undertaken in the last two years: new spectral types, more objects, additional information, and coordination with CDS. We also present updates for the Galactic O-Star Spectroscopic Survey (GOSSS). A new paper (GOSSS-III) has been published and ˜ 1000 targets have been observed since 2014. Four new setups have been added to our lineup and for two of them we have already obtained over 100 spectra: with OSIRIS at the 10.4 m GTC we are observing northern dim stars and with FRODOspec at the 2.0 m Liverpool Telescope we are observing northern bright stars. Finally, we also make available new versions of MGB, the spectral classification tool associated with the project, and of the GOSSS grid of spectroscopic standards.

Spatially correlated heterogeneous aspirations to enhance network reciprocity

NASA Astrophysics Data System (ADS)

Tanimoto, Jun; Nakata, Makoto; Hagishima, Aya; Ikegaya, Naoki

2012-02-01

Perc & Wang demonstrated that aspiring to be the fittest under conditions of pairwise strategy updating enhances network reciprocity in structured populations playing 2×2 Prisoner's Dilemma games (Z. Wang, M. Perc, Aspiring to the fittest and promoted of cooperation in the Prisoner's Dilemma game, Physical Review E 82 (2010) 021115; M. Perc, Z. Wang, Heterogeneous aspiration promotes cooperation in the Prisoner's Dilemma game, PLOS one 5 (12) (2010) e15117). Through numerical simulations, this paper shows that network reciprocity is even greater if heterogeneous aspirations are imposed. We also suggest why heterogeneous aspiration fosters network reciprocity. It distributes strategy updating speed among agents in a manner that fortifies the initially allocated cooperators' clusters against invasion. This finding prompted us to further enhance the usual heterogeneous aspiration cases for heterogeneous network topologies. We find that a negative correlation between degree and aspiration level does extend cooperation among heterogeneously structured agents.

Guide to Modelling & Simulation (M&S) for NATO Network-Enabled Capability (M&S for NNEC) (Guide de la modelisation et de la simulation (M&S) pour las NATO network-enabled capability (M&S de la NNEC))

DTIC Science & Technology

2010-02-01

interdependencies, and then modifying plans according to updated projections. This is currently an immature area where further research is required. The...crosscutting.html. [7] Zeigler, B.P. and Hammonds, P. (2007). “Modelling and Simulation- Based Data Engineering: Introducing Pragmatics and Ontologies for...the optimum benefit to be obtained and while immature , ongoing research needs to be maintained. 20) Use of M&S to support complex operations needs

The Economic Impact of Texas A&M University-Corpus Christi on the Corpus Christi Metropolitan Statistical Areas: 1998 Update.

ERIC Educational Resources Information Center

Texas A and M Univ., Corpus Christi.

A study was conducted to examine the socioeconomic impact of Texas A&M University-Corpus Christi (TAMU-CC) on the surrounding community. This study was a follow-up to a previous examination of the economic relationship between the university and the community. The current study examined the short-term measurable economic impact of university…

Short-Term Memory after All: Comment on Sederberg, Howard, and Kahana (2008)

ERIC Educational Resources Information Center

Usher, Marius; Davelaar, Eddy J.; Haarmann, Henk J.; Goshen-Gottstein, Yonatan

2008-01-01

P. B. Sederberg, M. W. Howard, and M. J. Kahana have proposed an updated version of the temporal-context model (TCM-A). In doing so, they accepted the challenge of developing a single-store model to account for the dissociations between short- and long-term recency effects that were reviewed by E. J. Davelaar, Y. Goshen-Gottstein, A. Ashkenazi, H.…

ST Elevation in AVR: When Time May Not Mean Muscle

DTIC Science & Technology

2017-10-31

for Cardiovascular Angiography and Interventions (/) --1 m (/) ~ --1 ) • ::J CD z Q) 0 0... :J Q) I < (/) --1 ;a m ~ L..-. __ - c... disease in patients with non-ST-segment elevation acute coronary syndrome. Am J Cardiol 2011;107(4):495-500. • Smith SW. Updates on the electrocardiogram in acute coronary syndromes. Curr Emerg Hosp Med Rep 2012;1{1):43-52.

Transitioning the Tactical Marine Corps to IPv6

DTIC Science & Technology

2011-09-01

SUT System Under Test SYSCOM Systems Command (synonymous with MCSC) TCP Transmission Control Protocol TDS Tactical Data Systems TDN...capability to provide services to the Marine Corps Tactical Data Systems ( TDS ) and other DDS-M systems. The 2 DDS-M can function as the file server...Intelligence ( ATI ) program provides comprehensive application protocols and attacks, as well as feature updates and responsive service and support with

75 FR 13344 - Revised Meeting Time for Citizens Coinage Advisory Committee March 2010 Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... DEPARTMENT OF THE TREASURY United States Mint Revised Meeting Time for Citizens Coinage Advisory...: March 23, 2010. Time: 2:30 p.m. to 5 p.m. Location: 8th Floor Boardroom, United States Mint, 801 9th... call 202-354-7502 for the latest update on meeting time and room location. In accordance with 31 U.S.C...

Subconjunctival hemorrhage

MedlinePlus

... 22. Review Date 5/10/2017 Updated by: Franklin W. Lusby, MD, ophthalmologist, Lusby Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Bleeding Read more Eye ...

75 FR 3489 - Notice of Public Meeting, Eastern Montana Resource Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-21

...: Miles City and Billings Field Office manager updates, subcommittee briefings, work sessions and other... provided above. Dated: January 8, 2010. M. Elaine Raper, District Manager. [FR Doc. 2010-1104 Filed 1-20-10...

77 FR 13621 - Notice of Public Meeting, Eastern Montana Resource Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-07

... Office manager updates, subcommittee briefings, work sessions and other issues that the council may raise..., 2012. M. Elaine Raper, Eastern Montana--Dakotas District Manager. [FR Doc. 2012-5492 Filed 3-6-12; 8:45...

Genetics Home Reference: congenital afibrinogenemia

MedlinePlus

... Neerman-Arbez M. FGB mutations leading to congenital quantitative fibrinogen deficiencies: an update and report of four ... R, Staeger P, Antonarakis SE, Morris MA. Molecular analysis of the fibrinogen gene cluster in 16 patients with congenital afibrinogenemia: novel truncating ... Support USA. ...

C-130J Human Vibration

DTIC Science & Technology

2005-08-01

Hulshof , 1999; Dupuis & Zerlett, 1986; Kittusamy & Buchholz, 2004; Seidel, 1993). There is also evidence of intervertebral disc problems and...Bovenzi, M., & Hulshof , C.T.J. (1999). An updated review of epidemiologic studies on the relationship between exposure to whole-body vibration and

Update on High-Resolution Geodetically Controlled LROC Polar Mosaics

NASA Astrophysics Data System (ADS)

Archinal, B.; Lee, E.; Weller, L.; Richie, J.; Edmundson, K.; Laura, J.; Robinson, M.; Speyerer, E.; Boyd, A.; Bowman-Cisneros, E.; Wagner, R.; Nefian, A.

2015-10-01

We describe progress on high-resolution (1 m/pixel) geodetically controlled LROC mosaics of the lunar poles, which can be used for locating illumination resources (for solar power or cold traps) or landing site and surface operations planning.

An updated review of the genus Martensopoda Jäger, 2006 (Araneae: Sparassidae: Heteropodinae).

PubMed

Sankaran, Pradeep M; Malamel, Jobi J; Joseph, Mathew M; Sebastian, Pothalil A

2015-03-26

A new species of the huntsman spider genus Martensopoda Jäger, 2006, M. sanctor sp. nov., is described and illustrated from the southern Western Ghats of India. Detailed first description and illustration of the male of M. minuscula (Reimoser, 1934) with a redescription and illustration of its female are provided. The female of M. transversa Jäger, 2006 is redescribed and illustrated. An identification key and a distribution map of all three Martensopoda species are presented.

Updated methods for traffic impact analysis, including evaluation of innovative intersection designs.

DOT National Transportation Integrated Search

2013-12-01

In 1992, an Applicants Guide and a Reviewers Guide to Traffic Impact Analyses to standardize the methodologies for conducting traffic : impact analyses (TIAs) in Indiana were developed for the Indiana Department of Transportation (INDOT). The m...

House Committee on Veterans' Affairs

MedlinePlus

... Phil Roe, M.D. Visit Chairman Roe's Website Twitter Updates Follow @HouseVetAffairs HouseVetAffairs @HouseVetAffairs a minute ago ... FRI 11/17) at 2pm ET for a Twitter Q&A. Ask questions using #askVBA . h… HouseVetAffairs @ ...

Improving Inspection and Maintenance Performance and On-board Diagnostics Monitor Readiness Memo

EPA Pesticide Factsheets

This EPA memorandum transmits an updated list of vehicles that exhibit issues related to OBD (on board diagnostics) monitor readiness and makes suggestions for how Inspection/Maintenance (I/M) programs can improve operational performance by addressing

Lung transplant

MedlinePlus

... ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 106. Solomon M, Grasemann H, Keshavjee S. Pediatric lung transplantation. Pediatr Clin North Am . 2010;57(2):375-391. PMID: 20371042 www.ncbi.nlm.nih.gov/pubmed/20371042 . Review Date 4/12/2017 Updated by: Mary C. Mancini, MD, ...

Sweet clover poisoning

USDA-ARS?s Scientific Manuscript database

Sweet clover poisoning occurs when spoiled sweet clover (Melilotus officinalis and M. alva) hay or silage that contain dicumarol are consumed by livestock. This updated chapter is a succinct review of the clinical disease and pathologic lesions of poisoning. It also reviews current strategies and ...

Update on Comparative Genomics of Legumes

USDA-ARS?s Scientific Manuscript database

This year marks the essential completion of the genome sequences of Glycine max, Medicago truncatula, and Lotus japonicus (soybean, barrel medic, and birdsfoot trefoil, respectively). The impact of these assembled, annotated genomes will be enormous. L. japonicus and M. truncatula, both forage crop...

When you need to gain more weight during pregnancy

MedlinePlus

... chap 10. West EH, Hark L, Catalano PM. Nutrition during pregnancy. In: Gabbe SG, Niebyl JR, Simpson JL, et ... update 03/09/2017. Related MedlinePlus Health Topics Pregnancy and Nutrition Browse the Encyclopedia A.D.A.M., Inc. ...

Staging Lung Cancer: Metastasis.

PubMed

Shroff, Girish S; Viswanathan, Chitra; Carter, Brett W; Benveniste, Marcelo F; Truong, Mylene T; Sabloff, Bradley S

2018-05-01

The updated eighth edition of the tumor, node, metastasis (TNM) classification for lung cancer includes revisions to T and M descriptors. In terms of the M descriptor, the classification of intrathoracic metastatic disease as M1a is unchanged from TNM-7. Extrathoracic metastatic disease, which was classified as M1b in TNM-7, is now subdivided into M1b (single metastasis, single organ) and M1c (multiple metastases in one or multiple organs) descriptors. In this article, the rationale for changes in the M descriptors, the utility of preoperative staging with PET/computed tomography, and the treatment options available for patients with oligometastatic disease are discussed. Copyright © 2018 Elsevier Inc. All rights reserved.

KEY COMPARISON Update of the BIPM.RI(II)-K1.Tc-99m comparison of activity measurements for the radionuclide 99mTc to include new results for the LNE-LNHB and the NPL

NASA Astrophysics Data System (ADS)

Michotte, C.; Courte, S.; Ratel, G.; Moune, M.; Johansson, L.; Keightley, J.

2010-01-01

In 2007 and 2008 respectively, the Laboratoire national de métrologie et d'essais-Laboratoire national Henri Becquerel (LNE-LNHB), France and the National Physical Laboratory (NPL), UK, submitted ampoules with between 10 MBq and 130 MBq activity of 99mTc to the International Reference System (SIR), to update their results in the BIPM.RI(II)-K1.Tc-99m comparison. Together with the four other national metrology institutes (NMI) that are participants, thirteen samples have been submitted since 1983. The key comparison reference value (KCRV) has been recalculated to include the latest primary results of the PTB and the LNE-LNHB as this makes the evaluation more robust. The degrees of equivalence between each equivalent activity measured in the SIR are given in the form of a matrix for all six NMIs. A graphical presentation is also given. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section II, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Vapor Intrusion Assessment and Mitigation 2012

DTIC Science & Technology

2012-03-26

1 Geosyntec 0 consultants Vapor Intrusion Assessment and Mitigation 2012 Robert Ettinger, M.S., P.E., Todd McAiary, M.Sc., P.Eng., P.G...REPORT DATE 26 MAR 2012 2. REPORT TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Vapor Intrusion Assessment and...Updates • Typical Assessment Approaches and Common Challenges • Methods to Distinguish Background Sources (McHugh) • Significance • Compound

Coordinating Learning Agents for Active Information Collection

DTIC Science & Technology

2011-06-30

the experiments were not particularly sensitive to this parameter. By limiting the number of actions that are updated (DANT-L in black/ dark ), the...Bazzan, A. and Ossowski, S. (eds.), Applications of Agent Technology in Traffic and Transportation (Springer, 2005). [19] Mataric , M. J., Coordination...organizing market (1998), preprint cond- mat/9802177. [19] Jones, C. and Mataric , M. J., Adaptive division of labor in large-scale multi-robot systems, in IEEE

psRNATarget: a plant small RNA target analysis server (2017 release).

PubMed

Dai, Xinbin; Zhuang, Zhaohong; Zhao, Patrick Xuechun

2018-04-30

Plant regulatory small RNAs (sRNAs), which include most microRNAs (miRNAs) and a subset of small interfering RNAs (siRNAs), such as the phased siRNAs (phasiRNAs), play important roles in regulating gene expression. Although generated from genetically distinct biogenesis pathways, these regulatory sRNAs share the same mechanisms for post-translational gene silencing and translational inhibition. psRNATarget was developed to identify plant sRNA targets by (i) analyzing complementary matching between the sRNA sequence and target mRNA sequence using a predefined scoring schema and (ii) by evaluating target site accessibility. This update enhances its analytical performance by developing a new scoring schema that is capable of discovering miRNA-mRNA interactions at higher 'recall rates' without significantly increasing total prediction output. The scoring procedure is customizable for the users to search both canonical and non-canonical targets. This update also enables transmitting and analyzing 'big' data empowered by (a) the implementation of multi-threading chunked file uploading, which can be paused and resumed, using HTML5 APIs and (b) the allocation of significantly more computing nodes to its back-end Linux cluster. The updated psRNATarget server has clear, compelling and user-friendly interfaces that enhance user experiences and present data clearly and concisely. The psRNATarget is freely available at http://plantgrn.noble.org/psRNATarget/.

ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments.

PubMed

Chèneby, Jeanne; Gheorghe, Marius; Artufel, Marie; Mathelier, Anthony; Ballester, Benoit

2018-01-04

With this latest release of ReMap (http://remap.cisreg.eu), we present a unique collection of regulatory regions in human, as a result of a large-scale integrative analysis of ChIP-seq experiments for hundreds of transcriptional regulators (TRs) such as transcription factors, transcriptional co-activators and chromatin regulators. In 2015, we introduced the ReMap database to capture the genome regulatory space by integrating public ChIP-seq datasets, covering 237 TRs across 13 million (M) peaks. In this release, we have extended this catalog to constitute a unique collection of regulatory regions. Specifically, we have collected, analyzed and retained after quality control a total of 2829 ChIP-seq datasets available from public sources, covering a total of 485 TRs with a catalog of 80M peaks. Additionally, the updated database includes new search features for TR names as well as aliases, including cell line names and the ability to navigate the data directly within genome browsers via public track hubs. Finally, full access to this catalog is available online together with a TR binding enrichment analysis tool. ReMap 2018 provides a significant update of the ReMap database, providing an in depth view of the complexity of the regulatory landscape in human. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

A comparative evaluation of two decompression procedures for technical diving using inflammatory responses: compartmental versus ratio deco.

PubMed

Spisni, Enzo; Marabotti, Claudio; De Fazio, Luigia; Valerii, Maria Chiara; Cavazza, Elena; Brambilla, Stefano; Hoxha, Klarida; L'Abbate, Antonio; Longobardi, Pasquale

2017-03-01

The aim of this study was to compare two decompression procedures commonly adopted by technical divers: the ZH-L16 algorithm modified by 30/85 gradient factors (compartmental decompression model, CDM) versus the 'ratio decompression strategy' (RDS). The comparison was based on an analysis of changes in diver circulating inflammatory profiles caused by decompression from a single dive. Fifty-one technical divers performed a single trimix dive to 50 metres' sea water (msw) for 25 minutes followed by enriched air (EAN50) and oxygen decompression. Twenty-three divers decompressed according to a CDM schedule and 28 divers decompressed according to a RDS schedule. Peripheral blood for detection of inflammatory markers was collected before and 90 min after diving. Venous gas emboli were measured 30 min after diving using 2D echocardiography. Matched groups of 23 recreational divers (dive to 30 msw; 25 min) and 25 swimmers were also enrolled as control groups to assess the effects of decompression from a standard air dive or of exercise alone on the inflammatory profile. Echocardiography at the single 30 min observation post dive showed no significant differences between the two decompression procedures. Divers adopting the RDS showed a worsening of post-dive inflammatory profile compared to the CDM group, with significant increases in circulating chemokines CCL2 (P = 0.001) and CCL5 (P = 0.006) levels. There was no increase in chemokines following the CDM decompression. The air scuba group also showed a statistically significant increase in CCL2 (P < 0.001) and CCL5 (P = 0.003) levels post dive. No cases of decompression sickness occurred. The ratio deco strategy did not confer any benefit in terms of bubbles but showed the disadvantage of increased decompression-associated secretion of inflammatory chemokines involved in the development of vascular damage.

Land Boundary Conditions for the Goddard Earth Observing System Model Version 5 (GEOS-5) Climate Modeling System: Recent Updates and Data File Descriptions

NASA Technical Reports Server (NTRS)

Mahanama, Sarith P.; Koster, Randal D.; Walker, Gregory K.; Takacs, Lawrence L.; Reichle, Rolf H.; De Lannoy, Gabrielle; Liu, Qing; Zhao, Bin; Suarez, Max J.

2015-01-01

The Earths land surface boundary conditions in the Goddard Earth Observing System version 5 (GEOS-5) modeling system were updated using recent high spatial and temporal resolution global data products. The updates include: (i) construction of a global 10-arcsec land-ocean lakes-ice mask; (ii) incorporation of a 10-arcsec Globcover 2009 land cover dataset; (iii) implementation of Level 12 Pfafstetter hydrologic catchments; (iv) use of hybridized SRTM global topography data; (v) construction of the HWSDv1.21-STATSGO2 merged global 30 arc second soil mineral and carbon data in conjunction with a highly-refined soil classification system; (vi) production of diffuse visible and near-infrared 8-day MODIS albedo climatologies at 30-arcsec from the period 2001-2011; and (vii) production of the GEOLAND2 and MODIS merged 8-day LAI climatology at 30-arcsec for GEOS-5. The global data sets were preprocessed and used to construct global raster data files for the software (mkCatchParam) that computes parameters on catchment-tiles for various atmospheric grids. The updates also include a few bug fixes in mkCatchParam, as well as changes (improvements in algorithms, etc.) to mkCatchParam that allow it to produce tile-space parameters efficiently for high resolution AGCM grids. The update process also includes the construction of data files describing the vegetation type fractions, soil background albedo, nitrogen deposition and mean annual 2m air temperature to be used with the future Catchment CN model and the global stream channel network to be used with the future global runoff routing model. This report provides detailed descriptions of the data production process and data file format of each updated data set.

Systemic Therapy for Stage IV Non-Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update.

PubMed

Hanna, Nasser; Johnson, David; Temin, Sarah; Baker, Sherman; Brahmer, Julie; Ellis, Peter M; Giaccone, Giuseppe; Hesketh, Paul J; Jaiyesimi, Ishmael; Leighl, Natasha B; Riely, Gregory J; Schiller, Joan H; Schneider, Bryan J; Smith, Thomas J; Tashbar, Joan; Biermann, William A; Masters, Gregory

2017-10-20

Purpose Provide evidence-based recommendations updating the 2015 ASCO guideline on systemic therapy for patients with stage IV non-small-cell lung cancer (NSCLC). Methods The ASCO NSCLC Expert Panel made recommendations based on a systematic review of randomized controlled trials from February 2014 to December 2016 plus the Cancer Care Ontario Program in Evidence-Based Care's update of a previous ASCO search. Results This guideline update reflects changes in evidence since the previous guideline update. Fourteen randomized controlled trials provide the evidence base; earlier phase trials also informed recommendation development. Recommendations New or revised recommendations include the following. Regarding first-line treatment for patients with non-squamous cell carcinoma or squamous cell carcinoma (without positive markers, eg, EGFR/ALK /ROS1), if the patient has high programmed death ligand 1 (PD-L1) expression, pembrolizumab should be used alone; if the patient has low PD-L1 expression, clinicians should offer standard chemotherapy. All other clinical scenarios follow 2015 recommendations. Regarding second-line treatment in patients who received first-line chemotherapy, without prior immune checkpoint therapy, if NSCLC tumor is positive for PD-L1 expression, clinicians should use single-agent nivolumab, pembrolizumab, or atezolizumab; if tumor has negative or unknown PD-L1 expression, clinicians should use nivolumab or atezolizumab. All immune checkpoint therapy is recommended alone plus in the absence of contraindications. For patients who received a prior first-line immune checkpoint inhibitor, clinicians should offer standard chemotherapy. For patients who cannot receive immune checkpoint inhibitor after chemotherapy, docetaxel is recommended; in patients with nonsquamous NSCLC, pemetrexed is recommended. In patients with a sensitizing EGFR mutation, disease progression after first-line epidermal growth factor receptor tyrosine kinase inhibitor therapy, and T790M mutation, osimertinib is recommended; if NSCLC lacks the T790M mutation, then chemotherapy is recommended. Patients with ROS1 gene rearrangement without prior crizotinib may be offered crizotinib, or if they previously received crizotinib, they may be offered chemotherapy.

Status of Fundamental Physics Program

NASA Technical Reports Server (NTRS)

Lee, Mark C.

2003-01-01

Update of the Fundamental Physics Program. JEM/EF Slip. 2 years delay. Reduced budget. Community support and advocacy led by Professor Nick Bigelow. Reprogramming led by Fred O Callaghan/JPL team. LTMPF M1 mission (DYNAMX and SUMO). PARCS. Carrier re baselined on JEM/EF.

77 FR 10529 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-22

... Current Investment Management Contract 8. Board Meeting Calendar Review 9. FRTIB Move Update 10. Roth... FEDERAL RETIREMENT THRIFT INVESTMENT BOARD Sunshine Act Meeting TIME AND DATE: 9 a.m. (Eastern.... Investment Performance Report c. Legislative Report 3. Review of Audit Recommendations 4. Audit Reports 5...

Synovial biopsy

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Autoimmune Diseases Read more Biopsy Read more Fungal ...

Carpal tunnel biopsy

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Amyloidosis Read more Biopsy Read more Carpal Tunnel ...

Metatarsus adductus

MedlinePlus

... 2016 Updated by: C. Benjamin Ma, MD, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Foot Injuries and Disorders Read more NIH MedlinePlus ...

Tendon repair

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Sprains and Strains Read more NIH MedlinePlus Magazine ...

Compartment syndrome

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Muscle Disorders Read more NIH MedlinePlus Magazine Read ...

Kyphosis

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Spine Injuries and Disorders Read more NIH MedlinePlus ...

Tenosynovitis

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Tendinitis Read more NIH MedlinePlus Magazine Read more ...

Bunion removal

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Toe Injuries and Disorders Read more NIH MedlinePlus ...

Replantation of digits

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Finger Injuries and Disorders Read more Toe Injuries ...

The Opioid Crisis | NIH MedlinePlus the Magazine

MedlinePlus

... disorder. Millions more suffer from chronic pain. Earlier this year, NIH Director Francis S. Collins, M.D., Ph.D., ... to manage pain. Stay tuned for updates on this important initiative from ... within the past year. More than 1.2 million emergency department visits ...

Utilizing topobathy LIDAR datasets to identify shoreline variations and to direct charting updates in the northern Gulf of Mexico

NASA Astrophysics Data System (ADS)

Gremillion, S. L.; Wright, S. L.

2017-12-01

Topographic and bathymetric light detection and ranging (LIDAR), remote sensing tools used to measure vertical elevations, are commonly employed to monitor shoreline fluctuations. Many of these publicly available datasets provide wide-swath, nearshore topobathy which can be used to extract shoreline positions and analyze coastlines experiencing the greatest temporal and spatial variability. This study focused on the shorelines of Mississippi's Jackson County to determine the minimum time for significant positional changes to occur, relative to currently published NOAA navigational charts. Many of these dynamic shorelines are vulnerable to relative sea level rise, storm surge, and coastal erosion. Utilizing LIDAR datasets from 1998-2015, shoreline positions were derived and analyzed against NOAA's Continually Updated Shoreline Product (CUSP) to recommend the frequency at which future surveys should be conducted. Advisement of charting updates were based upon the resolution of published charts, and the magnitude of observed variances. Jackson County shorelines were divided into four areas for analysis; the mainland, Horn Island, Petit Bois Island (PBI), and a dredge spoil area west of PBI. The mainland shoreline experienced an average change rate of +0.57 m/yr during the study period. This stability was due to engineering structures implemented in the early 1920's to protect against tropical storms. Horn Island, the most stable barrier island, changed an average of -1.34 m/yr, while PBI had an average change of -2.70 m/yr throughout. Lastly, the dredge spoil area changed by +9.06 m/yr. Based on these results, it is recommended that LIDAR surveys for Jackson County's mainland be conducted at least every two years, while surveys of the offshore barrier islands be conducted annually. Furthermore, insufficient LIDAR data for Round Island and the Round Island Marsh Restoration Project highlight these two areas as priority targets for future surveys.

Effects of efforts to optimise morbidity and mortality rounds to serve contemporary quality improvement and educational goals: a systematic review.

PubMed

Smaggus, Andrew; Mrkobrada, Marko; Marson, Alanna; Appleton, Andrew

2018-01-01

The quality and safety movement has reinvigorated interest in optimising morbidity and mortality (M&M) rounds. We performed a systematic review to identify effective means of updating M&M rounds to (1) identify and address quality and safety issues, and (2) address contemporary educational goals. Relevant databases (Medline, Embase, PubMed, Education Resource Information Centre, Cumulative Index to Nursing and Allied Health Literature, Healthstar, and Global Health) were searched to identify primary sources. Studies were included if they (1) investigated an intervention applied to M&M rounds, (2) reported outcomes relevant to the identification of quality and safety issues, or educational outcomes relevant to quality improvement (QI), patient safety or general medical education and (3) included a control group. Study quality was assessed using the Medical Education Research Study Quality Instrument and Newcastle-Ottawa Scale-Education instruments. Given the heterogeneity of interventions and outcome measures, results were analysed thematically. The final analysis included 19 studies. We identified multiple effective strategies (updating objectives, standardising elements of rounds and attaching rounds to a formal quality committee) to optimise M&M rounds for a QI/safety purpose. These efforts were associated with successful integration of quality and safety content into rounds, and increased implementation of QI interventions. Consistent effects on educational outcomes were difficult to identify, likely due to the use of methodologies ill-fitted for educational research. These results are encouraging for those seeking to optimise the quality and safety mission of M&M rounds. However, the inability to identify consistent educational effects suggests the investigation of M&M rounds could benefit from additional methodologies (qualitative, mixed methods) in order to understand the complex mechanisms driving learning at M&M rounds. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

JPSS-1 VIIRS Version 2 At-Launch Relative Spectral Response Characterization and Performance

NASA Technical Reports Server (NTRS)

Moeller, Chris; Schwarting, Thomas; McIntire, Jeff; Moyer, Dave; Zeng, Jinan

2017-01-01

The relative spectral response (RSR) characterization of the JPSS-1 VIIRS spectral bands has achieved at launch status in the VIIRS Data Analysis Working Group February 2016 Version 2 RSR release. The Version 2 release improves upon the June 2015 Version 1 release by including December 2014 NIST TSIRCUS spectral measurements of VIIRS VisNIR bands in the analysis plus correcting CO2 influence on the band M13 RSR. The T-SIRCUS based characterization is merged with the summer 2014 SpMA based characterization of VisNIR bands (Version 1 release) to yield a fused RSR for these bands, combining the strengths of the T-SIRCUS and the SpMA measurement systems. The M13 RSR is updated by applying a model-based correction to mitigate CO2 attenuation of the SpMA source signal that occurred during M13 spectral measurements. The Version 2 release carries forward the Version 1 RSR for those bands that were not updated (M8-M12, M14-M16AB, I3-I5, DNBMGS). The Version 2 release includes band average (overall detectors and subsamples) RSR plus supporting RSR for each detector and subsample. The at-launch band average RSR have been used to populate Look-Up Tables supporting the sensor data record and environmental data record at-launch science products. Spectral performance metrics show that JPSS-1VIIRS RSR are compliant on specifications with a few minor exceptions. The Version 2 release, which replaces the Version 1 release, is currently available on the password-protected NASA JPSS-1 eRooms under EAR99 control.

Implications of next generation attenuation ground motion prediction equations for site coefficients used in earthquake resistant design

USGS Publications Warehouse

Borcherdt, Roger D.

2014-01-01

Proposals are developed to update Tables 11.4-1 and 11.4-2 of Minimum Design Loads for Buildings and Other Structures published as American Society of Civil Engineers Structural Engineering Institute standard 7-10 (ASCE/SEI 7–10). The updates are mean next generation attenuation (NGA) site coefficients inferred directly from the four NGA ground motion prediction equations used to derive the maximum considered earthquake response maps adopted in ASCE/SEI 7–10. Proposals include the recommendation to use straight-line interpolation to infer site coefficients at intermediate values of (average shear velocity to 30-m depth). The NGA coefficients are shown to agree well with adopted site coefficients at low levels of input motion (0.1 g) and those observed from the Loma Prieta earthquake. For higher levels of input motion, the majority of the adopted values are within the 95% epistemic-uncertainty limits implied by the NGA estimates with the exceptions being the mid-period site coefficient, Fv, for site class D and the short-period coefficient, Fa, for site class C, both of which are slightly less than the corresponding 95% limit. The NGA data base shows that the median value  of 913 m/s for site class B is more typical than 760 m/s as a value to characterize firm to hard rock sites as the uniform ground condition for future maximum considered earthquake response ground motion estimates. Future updates of NGA ground motion prediction equations can be incorporated easily into future adjustments of adopted site coefficients using procedures presented herein. 

Update of Ireland's national average indoor radon concentration - Application of a new survey protocol.

PubMed

Dowdall, A; Murphy, P; Pollard, D; Fenton, D

2017-04-01

In 2002, a National Radon Survey (NRS) in Ireland established that the geographically weighted national average indoor radon concentration was 89 Bq m -3 . Since then a number of developments have taken place which are likely to have impacted on the national average radon level. Key among these was the introduction of amending Building Regulations in 1998 requiring radon preventive measures in new buildings in High Radon Areas (HRAs). In 2014, the Irish Government adopted the National Radon Control Strategy (NRCS) for Ireland. A knowledge gap identified in the NRCS was to update the national average for Ireland given the developments since 2002. The updated national average would also be used as a baseline metric to assess the effectiveness of the NRCS over time. A new national survey protocol was required that would measure radon in a sample of homes representative of radon risk and geographical location. The design of the survey protocol took into account that it is not feasible to repeat the 11,319 measurements carried out for the 2002 NRS due to time and resource constraints. However, the existence of that comprehensive survey allowed for a new protocol to be developed, involving measurements carried out in unbiased randomly selected volunteer homes. This paper sets out the development and application of that survey protocol. The results of the 2015 survey showed that the current national average indoor radon concentration for homes in Ireland is 77 Bq m -3 , a decrease from the 89 Bq m -3 reported in the 2002 NRS. Analysis of the results by build date demonstrate that the introduction of the amending Building Regulations in 1998 have led to a reduction in the average indoor radon level in Ireland. Copyright © 2016 Elsevier Ltd. All rights reserved.

Geostatistics and Bayesian updating for transmissivity estimation in a multiaquifer system in Manitoba, Canada.

PubMed

Kennedy, Paula L; Woodbury, Allan D

2002-01-01

In ground water flow and transport modeling, the heterogeneous nature of porous media has a considerable effect on the resulting flow and solute transport. Some method of generating the heterogeneous field from a limited dataset of uncertain measurements is required. Bayesian updating is one method that interpolates from an uncertain dataset using the statistics of the underlying probability distribution function. In this paper, Bayesian updating was used to determine the heterogeneous natural log transmissivity field for a carbonate and a sandstone aquifer in southern Manitoba. It was determined that the transmissivity in m2/sec followed a natural log normal distribution for both aquifers with a mean of -7.2 and - 8.0 for the carbonate and sandstone aquifers, respectively. The variograms were calculated using an estimator developed by Li and Lake (1994). Fractal nature was not evident in the variogram from either aquifer. The Bayesian updating heterogeneous field provided good results even in cases where little data was available. A large transmissivity zone in the sandstone aquifer was created by the Bayesian procedure, which is not a reflection of any deterministic consideration, but is a natural outcome of updating a prior probability distribution function with observations. The statistical model returns a result that is very reasonable; that is homogeneous in regions where little or no information is available to alter an initial state. No long range correlation trends or fractal behavior of the log-transmissivity field was observed in either aquifer over a distance of about 300 km.

Free Molecular Heat Transfer Programs for Setup and Dynamic Updating the Conductors in Thermal Desktop

NASA Technical Reports Server (NTRS)

Malroy, Eric T.

2007-01-01

The programs, arrays and logic structure were developed to enable the dynamic update of conductors in thermal desktop. The MatLab program FMHTPRE.m processes the Thermal Desktop conductors and sets up the arrays. The user needs to manually copy portions of the output to different input regions in Thermal Desktop. Also, Fortran subroutines are provided that perform the actual updates to the conductors. The subroutines are setup for helium gas, but the equations can be modified for other gases. The maximum number of free molecular conductors allowed is 10,000 for a given radiation task. Additional radiation tasks for FMHT can be generated to account for more conductors. Modifications to the Fortran subroutines may be warranted, when the mode of heat transfer is in the mixed or continuum mode. The FMHT Thermal Desktop model should be activated by using the "Case Set Manager" once the model is setup. Careful setup of the model is needed to avoid excessive solve times.

Left‐right asymmetry in the light of TOR: An update on what we know so far

PubMed Central

Casar Tena, Teresa

2015-01-01

The internal left‐right (LR) asymmetry is a characteristic that exists throughout the animal kingdom from roundworms over flies and fish to mammals. Cilia, which are antenna‐like structures protruding into the extracellular space, are involved in establishing LR asymmetry during early development. Humans who suffer from dysfunctional cilia often develop conditions such as heterotaxy, where internal organs appear to be placed randomly. As a consequence to this failure in asymmetry development, serious complications such as congenital heart defects (CHD) occur. The mammalian (or mechanistic) target of rapamycin (mTOR) pathway has recently emerged as an important regulator regarding symmetry breaking. The mTOR pathway governs fundamental processes such as protein translation or metabolism. Its activity can be transduced by two complexes, which are called TORC1 and TORC2, respectively. So far, only TORC1 has been implicated with asymmetry development and appears to require very precise regulation. A number of recent papers provided evidence that dysregulated TORC1 results in alterations of motile cilia and asymmetry defects. In here, we give an update on what we know so far of mTORC1 in LR asymmetry development. PMID:25943139

Z-Earth: 4D topography from space combining short-baseline stereo and lidar

NASA Astrophysics Data System (ADS)

Dewez, T. J.; Akkari, H.; Kaab, A. M.; Lamare, M. L.; Doyon, G.; Costeraste, J.

2013-12-01

The advent of free-of-charge global topographic data sets SRTM and Aster GDEM have enabled testing a host of geoscience hypotheses. Availability of such data is now considered standard, and though resolved at 30-m to 90-m pixel size, they are today regarded as obsolete and inappropriate given the regularly updated sub-meter imagery coming through web services like Google Earth. Two features will thus help meet the current topographic data needs of the Geoscience communities: field-scale-compatible elevation datasets (i.e. meter-scale digital models and sub-meter elevation precision) and provision for regularly updated topography to tackle earth surface changes in 4D, while retaining the key for success: data availability at no charge. A new space borne instrumental concept called Z-Earth has undergone phase 0 study at CNES, the French space agency to fulfill these aims. The scientific communities backing this proposal are that of natural hazards, glaciology and biomass. The system under study combines a short-baseline native stereo imager and a lidar profiler. This combination provides spatially resolved elevation swaths together with absolute along-track elevation control point profiles. Acquisition is designed for revisit time better than a year. Intended products not only target single pass digital surface models, color orthoimages and small footprint full-wave-form lidar profiles to update existing topographic coverage, but also time series of them. 3D change detection targets centimetre-scale horizontal precision and metric vertical precision, in complement of -now traditional- spectral change detection. To assess the actual concept value, two real-size experiments were carried out. We used sub-meter-scale Pleiades panchromatic stereo-images to generate digital surface models and check them against dense airborne lidar coverages, one heliborne set purposely flown in Corsica (50-100pts/sq.m) and a second one retrieved from OpenTopography.org (~10pts/sq.m.). In Corsica, over a challenging 45-degree-grade tree-covered mountain side, the Pleiades 2-m-grid-posting digital surface model described the topography with a median error of -4.75m +/-2.59m (NMAD). A planimetric bias between both datasets was found to be about 7m to the South. This planimetric misregistration, though well within Pleiades specifications, partly explains the dramatic effect on elevation difference. In the Redmond area (eastern Oregon), a very gentle desert landscape, elevation differences also contained a vertical median bias of -4.02m+/-1.22m (NMAD). Though here, sub-pixel planimetric registration between stereo DSM and lidar coverage was enforced. This real-size experiment hints that sub-meter accuracy for 2-m-grid-posting DSM is an achievable goal when combining stereoimaging and lidar.

78 FR 14521 - Agency Information Collection Extension With Changes

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

...-411, ``Coordinated Bulk Power Supply Program Report,'' Form EIA-826, ``Monthly Electric Utility Sales and Revenue Report with State Distributions,'' Form EIA-860, ``Annual Electric Generator Report,'' Form EIA-860M, ``Monthly Update to the Annual Electric Generator Report,'' Form EIA-861, ``Annual...

Limited range of motion

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Joint Disorders Read more NIH MedlinePlus Magazine Read ...

Liquid belt radiator design study

NASA Technical Reports Server (NTRS)

Teagan, W. P.; Fitzgerald, K. F.

1986-01-01

The Liquid Belt Radiator (LBR) is an advanced concept developed to meet the needs of anticipated future space missions. A previous study documented the advantages of this concept as a lightweight, easily deployable alternative to present day space heat rejection systems. The technical efforts associated with this study concentrate on refining the concept of the LBR as well as examining the issues of belt dynamics and potential application of the LBR to intermediate and high temperature heat rejection applications. A low temperature point design developed in previous work is updated assuming the use of diffusion pump oil, Santovac-6, as the heat transfer media. Additional analytical and design effort is directed toward determining the impact of interface heat exchanger, fluid bath sealing, and belt drive mechanism designs on system performance and mass. The updated design supports the earlier result by indicating a significant reduction in system specific system mass as compared to heat pipe or pumped fluid radiator concepts currently under consideration (1.3 kg/sq m versus 5 kg/sq m).

miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions.

PubMed

Chou, Chih-Hung; Shrestha, Sirjana; Yang, Chi-Dung; Chang, Nai-Wen; Lin, Yu-Ling; Liao, Kuang-Wen; Huang, Wei-Chi; Sun, Ting-Hsuan; Tu, Siang-Jyun; Lee, Wei-Hsiang; Chiew, Men-Yee; Tai, Chun-San; Wei, Ting-Yen; Tsai, Tzi-Ren; Huang, Hsin-Tzu; Wang, Chung-Yu; Wu, Hsin-Yi; Ho, Shu-Yi; Chen, Pin-Rong; Chuang, Cheng-Hsun; Hsieh, Pei-Jung; Wu, Yi-Shin; Chen, Wen-Liang; Li, Meng-Ju; Wu, Yu-Chun; Huang, Xin-Yi; Ng, Fung Ling; Buddhakosai, Waradee; Huang, Pei-Chun; Lan, Kuan-Chun; Huang, Chia-Yen; Weng, Shun-Long; Cheng, Yeong-Nan; Liang, Chao; Hsu, Wen-Lian; Huang, Hsien-Da

2018-01-04

MicroRNAs (miRNAs) are small non-coding RNAs of ∼ 22 nucleotides that are involved in negative regulation of mRNA at the post-transcriptional level. Previously, we developed miRTarBase which provides information about experimentally validated miRNA-target interactions (MTIs). Here, we describe an updated database containing 422 517 curated MTIs from 4076 miRNAs and 23 054 target genes collected from over 8500 articles. The number of MTIs curated by strong evidence has increased ∼1.4-fold since the last update in 2016. In this updated version, target sites validated by reporter assay that are available in the literature can be downloaded. The target site sequence can extract new features for analysis via a machine learning approach which can help to evaluate the performance of miRNA-target prediction tools. Furthermore, different ways of browsing enhance user browsing specific MTIs. With these improvements, miRTarBase serves as more comprehensively annotated, experimentally validated miRNA-target interactions databases in the field of miRNA related research. miRTarBase is available at http://miRTarBase.mbc.nctu.edu.tw/. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Service update

NASA Astrophysics Data System (ADS)

Zhang, Changjun

2018-04-01

Professor M Stanley Whittingham is a pioneering researcher in the development of lithium-ion batteries at Binghamton University and Kent Snyder leads battery research and development at Ford Motor Company. Nature Energy caught up with both during the Nature Conference on Materials Electrochemistry: Fundamentals and Applications held in China in January 2018.

Update: Our morels are named!

USDA-ARS?s Scientific Manuscript database

Preliminary investigations revealed that at least three morel species grow in Newfoundland and Labrador: Morchella importuna and two undescribed species, Mel-19 and Mel-36.1 M. importuna, the mulch morel, is known from Europe, Asia and North America.2,3 Mel-19 is cosmopolitan, known from Asia, Europ...

76 FR 77543 - Clinical Center; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Clinical Center; Notice of... Operating Plan and provide updates on selected organizational initiatives. Place: National Institutes of Health, Building 10, 10 Center Drive, CRC Medical Board Room 4-2551, Bethesda, MD 20892. Closed: 1:15 p.m...

Repair of webbed fingers or toes

MedlinePlus

... Updated by: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team. Finger Injuries and Disorders Read more Toe Injuries ...

78 FR 4166 - Notice of Public Meeting, Farmington District Resource Advisory Council Meeting, New Mexico

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-18

... Office manages the BLM Glade Run Recreation Area. The RAC also will receive an update on a delayed wild... fire season. At 1:30 p.m. on Thursday, February 21, there will be a one-hour public comment period. In...

77 FR 273 - Combined Notice of Filings #1

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-04

.... Applicants: Wolverine Power Supply Cooperative, Inc. Description: Market Power Update of Wolverine Power Supply Cooperative, Inc. Filed Date: 12/21/11. Accession Number: 20111221-5251. Comments Due: 5 p.m. ET 2...; ER10-2675-004. Applicants: Choctaw Generation Limited Partnership, Hot Spring Power Company, LLC,GDF...

Spleen removal - slideshow

MedlinePlus

... certain circulating white blood cells, as a part of the lymph system, and as a part of the immune system. Review Date 1/31/2017 Updated by: Mary ... urac.org). URAC's accreditation program is an independent audit to verify that ... follows rigorous standards of quality and accountability. A.D.A.M. is ...

The nurse theorists: 21st-century updates--Madeleine M. Leininger.

PubMed

Fawcett, Jacqueline

2002-04-01

This edited transcript of an interview with Madeleine Leininger presents Leininger's recent thoughts about the development and current state of the discipline of nursing, the development of the theory of culture care diversity and universality, methods for nursing research, mentorship, and transcultural nursing practice.

jsc2017m000462_Space-to-Ground_186_170727

NASA Image and Video Library

2017-07-27

Three new crew members are scheduled to launch to the ISS. The crew worked on the Capillary Structures Experiment. And what do astronauts do when they're not working? NASA's Space to Ground is your weekly update on what's happening aboard the International Space Station.

Overview of Suomi National Polar-Orbiting Partnership (NPP) Satellite Instrument Calibration and Validation

NASA Astrophysics Data System (ADS)

Weng, F.

2015-12-01

The Suomi National Polar-Orbiting Partnership (SNPP) satellite carries five instruments on board including ATMS, CrIS, VIIRS, OMPS and CERES. During the SNPP intensive calval, ATMS was pitched over to observe the cold space radiation. This unique data set was used for diagnostics of the ATMS scan-angle dependent bias and a scan-to-scan variation. A new algorithm is proposed to correct the ATMS scan angle dependent bias related to the reflector emission. ATMS radiometric calibration is also revised in IDPS with the full radiance processing (FRP). CrIS is the first Fourier transform Michelson interferometer and measures three infrared spectral bands from 650 to 1095, 1210 to 1750 and 2155 to 2550 cm-1 with spectral resolutions of 0.625 cm-1, respectively. Its spectral calibration is with an accuracy of better than 2 ppm and its noise is also well characterized with the Allan variance. Since CrIS was switched to the transmission of full spectral resolution (FSR) of RDR data to the ground in January 2015. The CrIS FSR SDR data are also produced offline at NOAA STAR. VIIRS has 22 spectral bands covering the spectrum between 0.412 μm and 12.01 μm, including 16 moderate resolution bands (M-bands) with a spatial resolution of 750 m at nadir, five imaging resolution bands (I-bands) with a spatial resolution of 375 m at nadir, and one day-night band (DNB) with a nearly-constant 750 m spatial resolution throughout the scan. The calibration of VIIRS reflective solar bands (RSB) requires a solar diffuser (SD) and a solar diffuser stability monitor (SDSM). Using the SNPP yaw maneuver data, SDSM screen transmission function can be updated to better capture the fine structures of the vignetting function. For OMPS nadir mapper (NM) and nadir profiler (NP), the detector signal-to-noise ratio, and sensor signal-to-noise ratio meet the system requirement. Detector gain and bias performance trends are generally stable. System linearity performance is stable and highly consistent with the prelaunch values. The recent updates on OMPS wavelength, solar flux and radiance coefficients have resulted in viewing angle dependent bias in the earth view observations. OMPS dark currents are updated weekly and monitored for further improving the radiometric calibration.

Accuracy assessment of building point clouds automatically generated from iphone images

NASA Astrophysics Data System (ADS)

Sirmacek, B.; Lindenbergh, R.

2014-06-01

Low-cost sensor generated 3D models can be useful for quick 3D urban model updating, yet the quality of the models is questionable. In this article, we evaluate the reliability of an automatic point cloud generation method using multi-view iPhone images or an iPhone video file as an input. We register such automatically generated point cloud on a TLS point cloud of the same object to discuss accuracy, advantages and limitations of the iPhone generated point clouds. For the chosen example showcase, we have classified 1.23% of the iPhone point cloud points as outliers, and calculated the mean of the point to point distances to the TLS point cloud as 0.11 m. Since a TLS point cloud might also include measurement errors and noise, we computed local noise values for the point clouds from both sources. Mean (μ) and standard deviation (σ) of roughness histograms are calculated as (μ1 = 0.44 m., σ1 = 0.071 m.) and (μ2 = 0.025 m., σ2 = 0.037 m.) for the iPhone and TLS point clouds respectively. Our experimental results indicate possible usage of the proposed automatic 3D model generation framework for 3D urban map updating, fusion and detail enhancing, quick and real-time change detection purposes. However, further insights should be obtained first on the circumstances that are needed to guarantee a successful point cloud generation from smartphone images.

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

PubMed Central

Rőszer, Tamás

2015-01-01

The alternatively activated or M2 macrophages are immune cells with high phenotypic heterogeneity and are governing functions at the interface of immunity, tissue homeostasis, metabolism, and endocrine signaling. Today the M2 macrophages are identified based on the expression pattern of a set of M2 markers. These markers are transmembrane glycoproteins, scavenger receptors, enzymes, growth factors, hormones, cytokines, and cytokine receptors with diverse and often yet unexplored functions. This review discusses whether these M2 markers can be reliably used to identify M2 macrophages and define their functional subdivisions. Also, it provides an update on the novel signals of the tissue environment and the neuroendocrine system which shape the M2 activation. The possible evolutionary roots of the M2 macrophage functions are also discussed. PMID:26089604

Best Value Acquisition Symposium and Continuous Acquisition and Life Cycle Support (CALS) Update Held in Eatontown, New Jersey on November 17-18, 1993

DTIC Science & Technology

1993-11-18

Satellite Commications/Milstar AMSEL- ACCA -A-AE Fort Mcimicth, New Jersey 07703 (908) 532-5486 MR. ROGER S. BERGE HQ, US Amy Ccauunicaticns-Electranics...o 0 0m IL W 0 0 2o Z 0 x0 0~LI 0i- 1 0 F8 20 (A ZI-m 0. WO 0 L 0>11 Z 0 0 A ’o m0J X I-z 4wE 0z. z 0OOL~( WZZ c Wx1>- MiAi Oz OMOXzO ILCl) 0>M CO)( 0

Update: Interim Guidance for Health Care Providers Caring for Pregnant Women with Possible Zika Virus Exposure - United States, July 2016.

PubMed

Oduyebo, Titilope; Igbinosa, Irogue; Petersen, Emily E; Polen, Kara N D; Pillai, Satish K; Ailes, Elizabeth C; Villanueva, Julie M; Newsome, Kim; Fischer, Marc; Gupta, Priya M; Powers, Ann M; Lampe, Margaret; Hills, Susan; Arnold, Kathryn E; Rose, Laura E; Shapiro-Mendoza, Carrie K; Beard, Charles B; Muñoz, Jorge L; Rao, Carol Y; Meaney-Delman, Dana; Jamieson, Denise J; Honein, Margaret A

2016-07-25

CDC has updated its interim guidance for U.S. health care providers caring for pregnant women with possible Zika virus exposure, to include the emerging data indicating that Zika virus RNA can be detected for prolonged periods in some pregnant women. To increase the proportion of pregnant women with Zika virus infection who receive a definitive diagnosis, CDC recommends expanding real-time reverse transcription-polymerase chain reaction (rRT-PCR) testing. Possible exposures to Zika virus include travel to or residence in an area with active Zika virus transmission, or sex* with a partner who has traveled to or resides in an area with active Zika virus transmission without using condoms or other barrier methods to prevent infection.(†) Testing recommendations for pregnant women with possible Zika virus exposure who report clinical illness consistent with Zika virus disease(§) (symptomatic pregnant women) are the same, regardless of their level of exposure (i.e., women with ongoing risk for possible exposure, including residence in or frequent travel to an area with active Zika virus transmission, as well as women living in areas without Zika virus transmission who travel to an area with active Zika virus transmission, or have unprotected sex with a partner who traveled to or resides in an area with active Zika virus transmission). Symptomatic pregnant women who are evaluated <2 weeks after symptom onset should receive serum and urine Zika virus rRT-PCR testing. Symptomatic pregnant women who are evaluated 2-12 weeks after symptom onset should first receive a Zika virus immunoglobulin (IgM) antibody test; if the IgM antibody test result is positive or equivocal, serum and urine rRT-PCR testing should be performed. Testing recommendations for pregnant women with possible Zika virus exposure who do not report clinical illness consistent with Zika virus disease (asymptomatic pregnant women) differ based on the circumstances of possible exposure. For asymptomatic pregnant women who live in areas without active Zika virus transmission and who are evaluated <2 weeks after last possible exposure, rRT-PCR testing should be performed. If the rRT-PCR result is negative, a Zika virus IgM antibody test should be performed 2-12 weeks after the exposure. Asymptomatic pregnant women who do not live in an area with active Zika virus transmission, who are first evaluated 2-12 weeks after their last possible exposure should first receive a Zika virus IgM antibody test; if the IgM antibody test result is positive or equivocal, serum and urine rRT-PCR should be performed. Asymptomatic pregnant women with ongoing risk for exposure to Zika virus should receive Zika virus IgM antibody testing as part of routine obstetric care during the first and second trimesters; immediate rRT-PCR testing should be performed when IgM antibody test results are positive or equivocal. This guidance also provides updated recommendations for the clinical management of pregnant women with confirmed or possible Zika virus infection. These recommendations will be updated when additional data become available.

JPSS-1 VIIRS version 2 at-launch relative spectral response characterization and performance

NASA Astrophysics Data System (ADS)

Moeller, Chris; Schwarting, Tom; McIntire, Jeff; Moyer, David I.; Zeng, Jinan

2016-09-01

The relative spectral response (RSR) characterization of the JPSS-1 VIIRS spectral bands has achieved "at launch" status in the VIIRS Data Analysis Working Group February 2016 Version 2 RSR release. The Version 2 release improves upon the June 2015 Version 1 release by including December 2014 NIST TSIRCUS spectral measurements of VIIRS VisNIR bands in the analysis plus correcting CO2 influence on the band M13 RSR. The T-SIRCUS based characterization is merged with the summer 2014 SpMA based characterization of VisNIR bands (Version 1 release) to yield a "fused" RSR for these bands, combining the strengths of the T-SIRCUS and the SpMA measurement systems. The M13 RSR is updated by applying a model-based correction to mitigate CO2 attenuation of the SpMA source signal that occurred during M13 spectral measurements. The Version 2 release carries forward the Version 1 RSR for those bands that were not updated (M8-M12, M14-M16A/B, I3-I5, DNBMGS). The Version 2 release includes band average (over all detectors and subsamples) RSR plus supporting RSR for each detector and subsample. The at-launch band average RSR have been used to populate Look-Up Tables supporting the sensor data record and environmental data record at-launch science products. Spectral performance metrics show that JPSS-1 VIIRS RSR are compliant on specifications with a few minor exceptions. The Version 2 release, which replaces the Version 1 release, is currently available on the password-protected NASA JPSS-1 eRooms under EAR99 control.

77 FR 486 - Combined Notice of Filings #1

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Combined Notice of Filings 1 Take notice... Updated Market Power Analysis and Request for Category 1 Seller Status of Portsmouth Genco, LLC, et al. Filed Date: 12/28/11. Accession Number: 20111228-5033. Comments Due: 5 p.m. ET 1/18/12. Docket Numbers...

76 FR 53896 - Combined Notice of Filings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

...: 5 p.m. Eastern Time on Tuesday, September 06, 2011. Docket Numbers: RP11-2410-000. Applicants: Gulf States Transmission LLC. Description: Gulf States Transmission LLC submits tariff filing per 154.402: Gulf States Transmission LLC ACA Tariff Update to be effective 10/1/2011. Filed Date: 08/22/2011...

Updating The Navy’s Recruit Quality Matrix: An Analysis of Educational Credentials and the Success of First-Term Sailors

DTIC Science & Technology

2004-03-01

Allison , Logistic Regression: Using the SAS System (Cary, NC: SAS Institute, Inc, 2001), 57. 23 using the likelihood ratio that SAS generates...21, respectively. 33 Jesse M. Rothstein, College Performance Predictions and the SAT ( Berkely , CA: UC

Canyon Country Ecosystems Research Site

Science.gov Websites

Soil Crust Home Crust 101 Advanced Gallery References CCERS Site Links updated: April 24, 2006 cyanobacteria, algae, lichens and mosses, that stabilize soil against wind and water erosion, enhance water 3400 m, and features a range of climates on both the same and different soil and bedrock substrates

75 FR 67393 - Notice of Public Meeting, Eastern Montana Resource Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-02

... Field Office manager updates, subcommittee briefings, work sessions and other issues that the council..., Interior, Montana, Billings and Miles City Field Offices. ACTION: Notice of public meeting. SUMMARY: In.... Dated: October 25, 2010. M. Elaine Raper, Manager, Eastern Montana--Dakotas District. [FR Doc. 2010...

76 FR 9049 - Notice of Public Meeting, Eastern Montana Resource Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-16

... Billings Field Office manager updates, subcommittee briefings, work sessions and other issues that the..., Interior, Montana, Billings and Miles City Field Offices. ACTION: Notice of public meeting. SUMMARY: In.... Dated: February 8, 2011. M. Elaine Raper, Manager, Eastern Montana--Dakotas District. [FR Doc. 2011-3545...

76 FR 43705 - Notice of Public Meeting, Eastern Montana Resource Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

... Field Office manager updates, subcommittee briefings, work sessions and other issues that the council..., Interior, Montana, Billings and Miles City Field Offices. ACTION: Notice of public meeting. SUMMARY: In.... Dated: July 8, 2011. M. Elaine Raper, Manager, Eastern Montana--Dakotas District. [FR Doc. 2011-18382...

Creative Thinking for Individuals and Teams. An Essay on Creative Thinking for Military Professionals

DTIC Science & Technology

2009-01-01

to creativity that are posited by Teresa Amabile in Creativity in Context. 11 The Amabile model of creativity presents a framework composed of...Associates, 2003), 396–429. 11 Teresa M. Amabile , Creativity in Context: Update to the Social Psychology of Creativity (Boulder, CO: Westview

78 FR 2978 - Combined Notice of Filings #2

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-15

.... Applicants: Lea Power Partners, LLC. Description: Lea Power Partners, LLC's Updated Market Power Analysis and....m. ET 1/28/13. Docket Numbers: ER12-72-002. Applicants: Public Service Company of New Mexico. Description: Public Service Company of New Mexico submits tariff filing per 35: PNM Filing of Former NITSA and...

77 FR 55799 - Sunshine Act Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-11

... Statutory Report Topic Approval and Scheduling of 2013 Briefings Adoption and Vote on 2013 USCCR Business Meeting Calendar Update on the Sex-Trafficking Briefing III. Management and Operations Chief of Regional.... ACTION: Notice of business meeting. DATE AND TIME: Friday, September 21, 2012; 9:30 a.m. EDT. PLACE: 1331...

75 FR 52799 - Notice of Public Hearing and Commission Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-27

... certain water resources projects; (2) compliance matters involving three projects; (3) action on a project... the following items: (1) Update on the SRBC Remote Water Quality Monitoring Network; (2) hydrologic..., Susquehanna County, Pa. 3. Project Sponsor: Seneca Resources Corporation. Pad ID: M. Pino H (ABR-20090933...

The Medicina Station Status Report

NASA Technical Reports Server (NTRS)

Orfei, Alessandro; Orlati, Andrea; Maccaferri, Giuseppe

2013-01-01

General information about the Medicina Radio Astronomy Station, the 32-m antenna status, and the staff in charge of the VLBI observations is provided. In 2012, the data from geodetic VLBI observations were acquired using the Mark 5A recording system with good results. Updates of the hardware were performed and are briefly described.

US Geological Survey customers speak out

USGS Publications Warehouse

Gillespie, S.; Snyder, G.

1995-01-01

Provides results of a customer survey carried out in 1994 by the US Geological Survey. Uses of cartographic products are classified, as are application areas, accuracy satisfaction, media, Digital Line Graph requirements in update, and frequency of product use. USGS responses and plans for the future are noted. -M.Blakemore

78 FR 40426 - Sunshine Act Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

... COMMISSION ON CIVIL RIGHTS Sunshine Act Notice AGENCY: United States Commission on Civil Rights. ACTION: Notice of Business Meeting. DATE AND TIME: Friday, July 12, 2013; 9:30 a.m. EST PLACE: 1331... Violation of Civil Rights Report Status Update on the Federal Civil Rights Engagement with Arab and Muslim...

STAR CLUSTERS IN M33: UPDATED UBVRI PHOTOMETRY, AGES, METALLICITIES, AND MASSES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fan, Zhou; De Grijs, Richard, E-mail: zfan@bao.ac.cn, E-mail: grijs@pku.edu.cn

2014-04-01

The photometric characterization of M33 star clusters is far from complete. In this paper, we present homogeneous UBVRI photometry of 708 star clusters and cluster candidates in M33 based on archival images from the Local Group Galaxies Survey, which covers 0.8 deg{sup 2} along the galaxy's major axis. Our photometry includes 387, 563, 616, 580, and 478 objects in the UBVRI bands, respectively, of which 276, 405, 430, 457, and 363 do not have previously published UBVRI photometry. Our photometry is consistent with previous measurements (where available) in all filters. We adopted Sloan Digital Sky Survey ugriz photometry for complementarymore » purposes, as well as Two Micron All Sky Survey near-infrared JHK photometry where available. We fitted the spectral-energy distributions of 671 star clusters and candidates to derive their ages, metallicities, and masses based on the updated PARSEC simple stellar populations synthesis models. The results of our χ{sup 2} minimization routines show that only 205 of the 671 clusters (31%) are older than 2 Gyr, which represents a much smaller fraction of the cluster population than that in M31 (56%), suggesting that M33 is dominated by young star clusters (<1 Gyr). We investigate the mass distributions of the star clusters—both open and globular clusters—in M33, M31, the Milky Way, and the Large Magellanic Cloud. Their mean values are log (M {sub cl}/M {sub ☉}) = 4.25, 5.43, 2.72, and 4.18, respectively. The fraction of open to globular clusters is highest in the Milky Way and lowest in M31. Our comparisons of the cluster ages, masses, and metallicities show that our results are basically in agreement with previous studies (where objects in common are available); differences can be traced back to differences in the models adopted, the fitting methods used, and stochastic sampling effects.« less

Updating the Skating Multistage Aerobic Test and Correction for V[Combining Dot Above]O2max Prediction Using a New Skating Economy Index in Elite Youth Ice Hockey Players.

PubMed

Allisse, Maxime; Bui, Hung Tien; Léger, Luc; Comtois, Alain-Steve; Leone, Mario

2018-05-07

Allisse, M, Bui, HT, Léger, L, Comtois, A-S, and Leone, M. Updating the skating multistage aerobic test and correction for V[Combining Dot Above]O2max prediction using a new skating economy index in elite youth ice hockey players. J Strength Cond Res XX(X): 000-000, 2018-A number of field tests, including the skating multistage aerobic test (SMAT), have been developed to predict V[Combining Dot Above]O2max in ice hockey players. The SMAT, like most field tests, assumes that participants who reach a given stage have the same oxygen uptake, which is not usually true. Thus, the objectives of this research are to update the V[Combining Dot Above]O2 values during the SMAT using a portable breath-by-breath metabolic analyzer and to propose a simple index of skating economy to improve the prediction of oxygen uptake. Twenty-six elite hockey players (age 15.8 ± 1.3 years) participated in this study. The oxygen uptake was assessed using a portable metabolic analyzer (K4b) during an on-ice maximal shuttle skate test. To develop an index of skating economy called the skating stride index (SSI), the number of skating strides was compiled for each stage of the test. The SMAT enabled the prediction of the V[Combining Dot Above]O2max (ml·kg·min) from the maximal velocity (m·s) and the SSI (skating strides·kg) using the following regression equation: V[Combining Dot Above]O2max = (14.94 × maximal velocity) + (3.68 × SSI) - 24.98 (r = 0.95, SEE = 1.92). This research allowed for the update of the oxygen uptake values of the SMAT and proposed a simple measure of skating efficiency for a more accurate evaluation of V[Combining Dot Above]O2max in elite youth hockey players. By comparing the highest and lowest observed SSI scores in our sample, it was noted that the V[Combining Dot Above]O2 values can vary by up to 5 ml·kg·min. Our results suggest that skating economy should be included in the prediction of V[Combining Dot Above]O2max to improve prediction accuracy.

A land cover change detection and classification protocol for updating Alaska NLCD 2001 to 2011

USGS Publications Warehouse

Jin, Suming; Yang, Limin; Zhu, Zhe; Homer, Collin G.

2017-01-01

Monitoring and mapping land cover changes are important ways to support evaluation of the status and transition of ecosystems. The Alaska National Land Cover Database (NLCD) 2001 was the first 30-m resolution baseline land cover product of the entire state derived from circa 2001 Landsat imagery and geospatial ancillary data. We developed a comprehensive approach named AKUP11 to update Alaska NLCD from 2001 to 2011 and provide a 10-year cyclical update of the state's land cover and land cover changes. Our method is designed to characterize the main land cover changes associated with different drivers, including the conversion of forests to shrub and grassland primarily as a result of wildland fire and forest harvest, the vegetation successional processes after disturbance, and changes of surface water extent and glacier ice/snow associated with weather and climate changes. For natural vegetated areas, a component named AKUP11-VEG was developed for updating the land cover that involves four major steps: 1) identify the disturbed and successional areas using Landsat images and ancillary datasets; 2) update the land cover status for these areas using a SKILL model (System of Knowledge-based Integrated-trajectory Land cover Labeling); 3) perform decision tree classification; and 4) develop a final land cover and land cover change product through the postprocessing modeling. For water and ice/snow areas, another component named AKUP11-WIS was developed for initial land cover change detection, removal of the terrain shadow effects, and exclusion of ephemeral snow changes using a 3-year MODIS snow extent dataset from 2010 to 2012. The overall approach was tested in three pilot study areas in Alaska, with each area consisting of four Landsat image footprints. The results from the pilot study show that the overall accuracy in detecting change and no-change is 90% and the overall accuracy of the updated land cover label for 2011 is 86%. The method provided a robust, consistent, and efficient means for capturing major disturbance events and updating land cover for Alaska. The method has subsequently been applied to generate the land cover and land cover change products for the entire state of Alaska.

Prop-fan data support study

NASA Technical Reports Server (NTRS)

Baum, J. A.; Dumais, P. J.; Mayo, M. G.; Metzger, F. B.; Shenkman, A. M.; Walker, G. G.

1978-01-01

Updated parametric prop-fan data packages are presented and the rationale used in developing the new prop-fan data is detailed. These data represent Hamilton Standard's projections of prop-fan characteristics for aircraft that are expected to be in-service in the 1985 to 1990 time frame. The basic prop-fan configuration was designed for efficient cruise operation at 0.8 Mach number and 10,668M altitude. The design blade tip speed is 244 mps and the design power loading is 301 KW/M squared.

Combining Multiple Types of Intelligence to Generate Probability Maps of Moving Targets

DTIC Science & Technology

2013-09-01

normalization coefficient k similar to Demspter-Shafer’s combination rule. d. Mass Mean This rule of combination is the most straightforward one... coefficient , we can state that without normalizing, the updated distribution is: fupdate t   qk k t M 1 qk n k t M        (3.3) 36...Lawrence, KS. Chen, Z. (2003). Bayesian filtering: From Kalman filters to particle filters and beyond. Technical report, McMaster University. Dempster

Development of a 30 m Spatial Resolution Land Cover of Canada: Contribution to the Harmonized North America Land Cover Dataset

NASA Astrophysics Data System (ADS)

Pouliot, D.; Latifovic, R.; Olthof, I.

2017-12-01

Land cover is needed for a large range of environmental applications regarding climate impacts and adaption, emergency response, wildlife habitat, air quality, water yield, etc. In Canada a 2008 user survey revealed that the most practical scale for provision of land cover data is 30 m, nationwide, with an update frequency of five years (Ball, 2008). In response to this need the Canada Centre for Remote Sensing has generated a 30 m land cover of Canada for the base year 2010 as part of a planned series of maps at the recommended five year update frequency. This land cover is the Canadian contribution to the North American Land Change Monitoring System initiative, which seeks to provide harmonized land cover across Canada, the United States, and Mexico. The methodology developed in this research utilized a combination of unsupervised and machine learning techniques to map land cover, blend results between mapping units, locally optimize results, and process some thematic attributes with specific features sets. Accuracy assessment with available field data shows it was on average 75% for the five study areas assessed. In this presentation an overview of the unique processing aspects, example results, and initial accuracy assessment will be discussed.

Measurement and Characterization of Space Shuttle Solid Rocket Motor Plume Acoustics

NASA Technical Reports Server (NTRS)

Kenny, Robert Jeremy

2009-01-01

NASA's current models to predict lift-off acoustics for launch vehicles are currently being updated using several numerical and empirical inputs. One empirical input comes from free-field acoustic data measured at three Space Shuttle Reusable Solid Rocket Motor (RSRM) static firings. The measurements were collected by a joint collaboration between NASA - Marshall Space Flight Center, Wyle Labs, and ATK Launch Systems. For the first time NASA measured large-thrust solid rocket motor plume acoustics for evaluation of both noise sources and acoustic radiation properties. Over sixty acoustic free-field measurements were taken over the three static firings to support evaluation of acoustic radiation near the rocket plume, far-field acoustic radiation patterns, plume acoustic power efficiencies, and apparent noise source locations within the plume. At approximately 67 m off nozzle centerline and 70 m downstream of the nozzle exit plan, the measured overall sound pressure level of the RSRM was 155 dB. Peak overall levels in the far field were over 140 dB at 300 m and 50-deg off of the RSRM thrust centerline. The successful collaboration has yielded valuable data that are being implemented into NASA's lift-off acoustic models, which will then be used to update predictions for Ares I and Ares V liftoff acoustic environments.

Documentation for the 2014 update of the United States national seismic hazard maps

USGS Publications Warehouse

Petersen, Mark D.; Moschetti, Morgan P.; Powers, Peter M.; Mueller, Charles S.; Haller, Kathleen M.; Frankel, Arthur D.; Zeng, Yuehua; Rezaeian, Sanaz; Harmsen, Stephen C.; Boyd, Oliver S.; Field, Edward; Chen, Rui; Rukstales, Kenneth S.; Luco, Nico; Wheeler, Russell L.; Williams, Robert A.; Olsen, Anna H.

2014-01-01

The national seismic hazard maps for the conterminous United States have been updated to account for new methods, models, and data that have been obtained since the 2008 maps were released (Petersen and others, 2008). The input models are improved from those implemented in 2008 by using new ground motion models that have incorporated about twice as many earthquake strong ground shaking data and by incorporating many additional scientific studies that indicate broader ranges of earthquake source and ground motion models. These time-independent maps are shown for 2-percent and 10-percent probability of exceedance in 50 years for peak horizontal ground acceleration as well as 5-hertz and 1-hertz spectral accelerations with 5-percent damping on a uniform firm rock site condition (760 meters per second shear wave velocity in the upper 30 m, VS30). In this report, the 2014 updated maps are compared with the 2008 version of the maps and indicate changes of plus or minus 20 percent over wide areas, with larger changes locally, caused by the modifications to the seismic source and ground motion inputs.

Closure Plan for the Area 5 Radioactive Waste Management Site at the Nevada Test Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Management

The Area 5 Radioactive Waste Management Site (RMWS) at the Nevada Test Site (NTS) is managed and operated by National Security Technologies, LLC (NSTec), for the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO). This document is the first update of the preliminary closure plan for the Area 5 RWMS at the NTS that was presented in the Integrated Closure and Monitoring Plan (DOE, 2005a). The major updates to the plan include a new closure schedule, updated closure inventory, updated site and facility characterization data, the Title II engineering cover design, and the closure processmore » for the 92-Acre Area of the RWMS. The format and content of this site-specific plan follows the Format and Content Guide for U.S. Department of Energy Low-Level Waste Disposal Facility Closure Plans (DOE, 1999a). This interim closure plan meets closure and post-closure monitoring requirements of the order DOE O 435.1, manual DOE M 435.1-1, Title 40 Code of Federal Regulations (CFR) Part 191, 40 CFR 265, Nevada Administrative Code (NAC) 444.743, and Resource Conservation and Recovery Act (RCRA) requirements as incorporated into NAC 444.8632. The Area 5 RWMS accepts primarily packaged low-level waste (LLW), low-level mixed waste (LLMW), and asbestiform low-level waste (ALLW) for disposal in excavated disposal cells.« less

QWIPs at IRnova, a status update

NASA Astrophysics Data System (ADS)

Martijn, Henk; Gamfeldt, Anders; Asplund, Carl; Smuk, Sergiy; Kataria, Himanshu; Costard, Eric

2016-05-01

IRnova has a long history of producing QWIPs for the LWIR band. In this paper we give an overview of the current products (FPAs with 640x480 and 384x288 pixels respectively, and 25 μm pitch) and their performance. Their superior stability and uniformity inherent to detectors based on III/V material system will be demonstrated. Furthermore, an IDCA specifically designed for hand-held systems used for the detection of SF6 gas using a 0.5 W cooler will be presented. The detector format is 320x256 pixels with 30 μm pitch using the ISC9705 read out circuit. The peak wavelength is at 10.55 μm and the NETD is 22 mK.

Simulation of SOA formation and composition from oxidation of toluene and m-xylene in chamber experiments

NASA Astrophysics Data System (ADS)

Xu, J.; Liu, Y.; Nakao, S.; Cocker, D.; Griffin, R. J.

2013-12-01

Aromatic hydrocarbons contribute an important fraction of anthropogenic reactive volatile organic compounds (VOCs) in the urban atmosphere. Photo-oxidation of aromatic hydrocarbons leads to secondary organic products that have decreased volatilities or increased solubilities and can form secondary organic aerosol (SOA). Despite the crucial role of aromatic-derived SOA in deteriorating air quality and harming human health, its formation mechanism is not well understood and model simulation of SOA formation still remains difficult. The dependence of aromatic SOA formation on nitrogen oxides (NOx) is not captured fully by most SOA formation models. Most models predict SOA formation under high NOx levels well but underestimate SOA formation under low NOx levels more representative of the ambient atmosphere. Thus, it is crucial to investigate the NOx-dependent chemistry in aromatic photo-oxidation systems and correspondingly update SOA formation models. In this study, NOx-dependent mechanisms of toluene and m-xylene SOA formation are updated using the gas-phase Caltech Atmospheric Chemistry Mechanism (CACM) coupled to a gas/aerosol partitioning model. The updated models were optimized by comparing to eighteen University of California, Riverside United States Environmental Protection Agency (EPA) chamber experiment runs under both high and low NOx conditions. Correction factors for vapor pressures imply uncharacterized aerosol-phase association chemistry. Simulated SOA speciation implies the importance of ring-opening products in governing SOA formation (up to 40%~60% for both aromatics). The newly developed model can predict strong decreases of m-xylene SOA yield with increasing NOx. Speciation distributions under varied NOx levels implies that the well-known competition between RO2 + HO2 and RO2 + NO (RO2 = peroxide bicyclic radical) may not be the only factor influencing SOA formation. The reaction of aromatic peroxy radicals with NO competing with its self-cyclization also affects NOx-dependence of SOA formation. Comparison of SOA formation yield and composition between two aromatics implies aldehyde/ketone chemistry from ring-opening route and chemistry for phenolic route play important roles in governing SOA formation and that ring-opening aldehydes and phenolic nitrates are produced to a greater extent in the toluene system, leading to higher SOA yields for toluene than for m-xylene.

Historical Review of Atomic Frequency Standards Used in Space Systems - 10 Year Update

DTIC Science & Technology

2007-01-01

section on 2006 predictions. The authors would like to thank Peter Cash, Bernardo Jaduszliwer, Bob Kern, Robert Lutwak , John Prestage, Bill Riley, and...258- 262. [17] R. Lutwak , D. Emmons, R. M. Garvey, and P. Vlitas, 2003, “Optically pumped cesium-beam frequency standard for GPS-III,” in

Captions, Consistency, Creativity, and the Consensual Assessment Technique: New Evidence of Reliability

ERIC Educational Resources Information Center

Kaufman, James C.; Lee, Joohyun; Baer, John; Lee, Soonmook

2007-01-01

The consensual assessment technique (CAT) is a measurement tool for creativity research in which appropriate experts evaluate creative products [Amabile, T. M. (1996). "Creativity in context: Update to the social psychology of creativity." Boulder, CO: Westview]. However, the CAT is hampered by the time-consuming nature of the products (asking…

78 FR 21123 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-09

... Corporation's Board of Directors will meet in open session at 3:00 p.m. on Thursday, April 11, 2013, to... anticipated. These matters will be resolved with a single vote unless a member of the Board of Directors... Directors' Meetings. Memorandum re: Update to the Statement of Policy on Development and Review of FDIC...

75 FR 8689 - Combined Notice of Filings #1

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-25

... updated market power analysis for study period of 12/1/06-11/ 30/07. Filed Date: 02/01/2010. Accession... Power & Light Company and KCP & L Greater Missouri Operations Company. Filed Date: 01/29/2010 Accession... Date: 01/29/2010 Accession Number: 20100129-5115 Comment Date: 5 p.m. Eastern Time on Friday, February...

78 FR 65960 - Sunshine Act Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-04

... MORRIS K. UDALL AND STEWART L. UDALL FOUNDATION Sunshine Act Meetings TIME AND DATE: 9:00 a.m. to... section has been updated.) PLACE: The offices of the Morris K. Udall and Stewart L. Udall Foundation, 130... David J. Hayes the position of Trustee Emeritus of the Morris K. Udall and Stewart L. Udall Foundation...

76 FR 43705 - Notice of Public Meeting, Dakotas Resource Advisory Council Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

... in the Dakotas. At these meetings, topics will include: North Dakota and South Dakota Field Office manager updates, subcommittee briefings, work sessions and other issues that the council may raise. All.... M. Elaine Raper, Manager, Eastern Montana, Dakotas District . [FR Doc. 2011-18376 Filed 7-20-11; 8...

Executive Functions Underlying Multiplicative Reasoning: Problem Type Matters

ERIC Educational Resources Information Center

Agostino, Alba; Johnson, Janice; Pascual-Leone, Juan

2010-01-01

We investigated the extent to which inhibition, updating, shifting, and mental-attentional capacity ("M"-capacity) contribute to children's ability to solve multiplication word problems. A total of 155 children in Grades 3-6 (8- to 13-year-olds) completed a set of multiplication word problems at two levels of difficulty: one-step and multiple-step…

75 FR 51242 - Fisheries of the South Atlantic; Southeast Data, Assessment, and Review (SEDAR); Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-19

... benchmarks, projects future population conditions, and recommends research and monitoring needs. Participants....--4 p.m. Assessment panelists will discuss data inputs to the stock assessment model and make recommendations for additional years of data to be updated in the model. New information on black sea bass life...

Ethnography, Step by Step (2nd Edition), by David M. Fetterman, Thousand Oaks, Ca: Sage, 1998..

ERIC Educational Resources Information Center

Green, Jennifer C.; Buell, James

2000-01-01

Reviews this edition, which like the first is primarily an organized presentation of fieldwork vignettes and instructive examples from research and evaluation contexts. The presentation is organized by the steps involved in ethnographic fieldwork. This edition is updated with references to electronic technology. (SLD)

Updated earthquake catalogue for seismic hazard analysis in Pakistan

NASA Astrophysics Data System (ADS)

Khan, Sarfraz; Waseem, Muhammad; Khan, Muhammad Asif; Ahmed, Waqas

2018-03-01

A reliable and homogenized earthquake catalogue is essential for seismic hazard assessment in any area. This article describes the compilation and processing of an updated earthquake catalogue for Pakistan. The earthquake catalogue compiled in this study for the region (quadrangle bounded by the geographical limits 40-83° N and 20-40° E) includes 36,563 earthquake events, which are reported as 4.0-8.3 moment magnitude (M W) and span from 25 AD to 2016. Relationships are developed between the moment magnitude and body, and surface wave magnitude scales to unify the catalogue in terms of magnitude M W. The catalogue includes earthquakes from Pakistan and neighbouring countries to minimize the effects of geopolitical boundaries in seismic hazard assessment studies. Earthquakes reported by local and international agencies as well as individual catalogues are included. The proposed catalogue is further used to obtain magnitude of completeness after removal of dependent events by using four different algorithms. Finally, seismicity parameters of the seismic sources are reported, and recommendations are made for seismic hazard assessment studies in Pakistan.

Catalyzed D-D stellarator reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sheffield, John; Spong, Donald A.

The advantages of using the catalyzed deuterium-deuterium (D-D) approach for a fusion reactor—lower and less energetic neutron flux and no need for a tritium breeding blanket—have been evaluated in previous papers, giving examples of both tokamak and stellarator reactors. This paper presents an update for the stellarator example, taking account of more recent empirical transport scaling results and design studies of lower-aspect-ratio stellarators. We use a modified version of the Generic Magnetic Fusion Reactor model to cost a stellarator-type reactor. Recently, this model has been updated to reflect the improved science and technology base and costs in the magnetic fusionmore » program. Furthermore, it is shown that an interesting catalyzed D-D, stellarator power plant might be possible if the following parameters could be achieved: R/ ≈ 4, required improvement factor to ISS04 scaling, F R = 0.9 to 1.15, ≈ 8.0% to 11.5%, Z eff ≈ 1.45 plus a relativistic temperature correction, fraction of fast ions lost ≈ 0.07, B m ≈ 14 to 16 T, and R ≈ 18 to 24 m.« less

CCD Parallaxes for 309 Late-type Dwarfs and Subdwarfs

NASA Astrophysics Data System (ADS)

Dahn, Conard C.; Harris, Hugh C.; Subasavage, John P.; Ables, Harold D.; Canzian, Blaise J.; Guetter, Harry H.; Harris, Fred H.; Henden, Arne H.; Leggett, S. K.; Levine, Stephen E.; Luginbuhl, Christian B.; Monet, Alice B.; Monet, David G.; Munn, Jeffrey A.; Pier, Jeffrey R.; Stone, Ronald C.; Vrba, Frederick J.; Walker, Richard L.; Tilleman, Trudy M.

2017-10-01

New, updated, and/or revised CCD parallaxes determined with the Strand Astrometric Reflector at the Naval Observatory Flagstaff Station are presented. Included are results for 309 late-type dwarf and subdwarf stars observed over the 30+ years that the program operated. For 124 of the stars, parallax determinations from other investigators have already appeared in the literature and we compare the different results. Also included here are new or updated VI photometry on the Johnson-Kron-Cousins system for all but a few of the faintest targets. Together with 2MASS JHK s near-infrared photometry, a sample of absolute magnitude versus color and color versus color diagrams are constructed. Because large proper motion was a prime criterion for targeting the stars, the majority turn out to be either M-type subdwarfs or late M-type dwarfs. The sample also includes 50 dwarf or subdwarf L-type stars, and four T dwarfs. Possible halo subdwarfs are identified in the sample based on tangential velocity, subluminosity, and spectral type. Residuals from the solutions for parallax and proper motion for several stars show evidence of astrometric perturbations.

Catalyzed D-D stellarator reactor

DOE PAGES

Sheffield, John; Spong, Donald A.

2016-05-12

The advantages of using the catalyzed deuterium-deuterium (D-D) approach for a fusion reactor—lower and less energetic neutron flux and no need for a tritium breeding blanket—have been evaluated in previous papers, giving examples of both tokamak and stellarator reactors. This paper presents an update for the stellarator example, taking account of more recent empirical transport scaling results and design studies of lower-aspect-ratio stellarators. We use a modified version of the Generic Magnetic Fusion Reactor model to cost a stellarator-type reactor. Recently, this model has been updated to reflect the improved science and technology base and costs in the magnetic fusionmore » program. Furthermore, it is shown that an interesting catalyzed D-D, stellarator power plant might be possible if the following parameters could be achieved: R/ ≈ 4, required improvement factor to ISS04 scaling, F R = 0.9 to 1.15, ≈ 8.0% to 11.5%, Z eff ≈ 1.45 plus a relativistic temperature correction, fraction of fast ions lost ≈ 0.07, B m ≈ 14 to 16 T, and R ≈ 18 to 24 m.« less

SEEDS Moving Groups and CHARIS Status Updates

NASA Technical Reports Server (NTRS)

McElwain, Michael

2012-01-01

We present the status update for the SEEDS Moving Groups category. To date, we have observed 59 targets and currently have more than 20 candidates. We also present the expected scientific capabilities of CHARIS, the Coronagraphic High Angular Resolution Imaging Spectrograph, which is being built for the Subaru 8.2 m telescope of the National Astronomical Observatory of Japan. CHARIS will be implemented behind the new extreme adaptive optics system at Subaru, SCExAO, and the existing 188-actuator system AO188. CHARIS will offer three observing modes over nearinfrared wavelengths from 0.9 to 2.4 microns (the y-, J-, H-, and K-bands), including a low-spectral-resolution mode covering this entire wavelength range and a high-resolution mode within a single band. With these capabilities, CHARIS will offer exceptional sensitivity for discovering giant exoplanets, and will enable detailed characterization of their atmospheres, CHARIS, the only planned high-contrast integral field spectrograph on an 8m-class telescope in the Northern Hemisphere, will complement the similar instruments such as Project 1640 at Palomar, and GPI and SPHERE in Chile.

Visual Target Tracking on the Mars Exploration Rovers

NASA Technical Reports Server (NTRS)

Kim, Won S.; Biesiadecki, Jeffrey J.; Ali, Khaled S.

2008-01-01

Visual Target Tracking (VTT) has been implemented in the new Mars Exploration Rover (MER) Flight Software (FSW) R9.2 release, which is now running on both Spirit and Opportunity rovers. Applying the normalized cross-correlation (NCC) algorithm with template image magnification and roll compensation on MER Navcam images, VTT tracks the target and enables the rover to approach the target within a few cm over a 10 m traverse. Each VTT update takes 1/2 to 1 minute on the rovers, 2-3 times faster than one Visual Odometry (Visodom) update. VTT is a key element to achieve a target approach and instrument placement over a 10-m run in a single sol in contrast to the original baseline of 3 sols. VTT has been integrated into the MER FSW so that it can operate with any combination of blind driving, Autonomous Navigation (Autonav) with hazard avoidance, and Visodom. VTT can either guide the rover towards the target or simply image the target as the rover drives by. Three recent VTT operational checkouts on Opportunity were all successful, tracking the selected target reliably within a few pixels.

Cost-effective handoff scheme based on mobility-aware dual pointer forwarding in proxy mobile IPv6 networks.

PubMed

Son, Seungsik; Jeong, Jongpil

2014-01-01

In this paper, a mobility-aware Dual Pointer Forwarding scheme (mDPF) is applied in Proxy Mobile IPv6 (PMIPv6) networks. The movement of a Mobile Node (MN) is classified as intra-domain and inter-domain handoff. When the MN moves, this scheme can reduce the high signaling overhead for intra-handoff/inter-handoff, because the Local Mobility Anchor (LMA) and Mobile Access Gateway (MAG) are connected by pointer chains. In other words, a handoff is aware of low mobility between the previously attached MAG (pMAG) and newly attached MAG (nMAG), and another handoff between the previously attached LMA (pLMA) and newly attached LMA (nLMA) is aware of high mobility. Based on these mobility-aware binding updates, the overhead of the packet delivery can be reduced. Also, we analyse the binding update cost and packet delivery cost for route optimization, based on the mathematical analytic model. Analytical results show that our mDPF outperforms the PMIPv6 and the other pointer forwarding schemes, in terms of reducing the total cost of signaling.

Retired A Stars Revisited: An Updated Giant Planet Occurrence Rate as a Function of Stellar Metallicity and Mass

NASA Astrophysics Data System (ADS)

Ghezzi, Luan; Montet, Benjamin T.; Johnson, John Asher

2018-06-01

Exoplanet surveys of evolved stars have provided increasing evidence that the formation of giant planets depends not only on stellar metallicity ([Fe/H]) but also on the mass ({M}\\star ). However, measuring accurate masses for subgiants and giants is far more challenging than it is for their main-sequence counterparts, which has led to recent concerns regarding the veracity of the correlation between stellar mass and planet occurrence. In order to address these concerns, we use HIRES spectra to perform a spectroscopic analysis on a sample of 245 subgiants and derive new atmospheric and physical parameters. We also calculate the space velocities of this sample in a homogeneous manner for the first time. When reddening corrections are considered in the calculations of stellar masses and a ‑0.12 {M}ȯ offset is applied to the results, the masses of the subgiants are consistent with their space velocity distributions, contrary to claims in the literature. Similarly, our measurements of their rotational velocities provide additional confirmation that the masses of subgiants with {M}\\star ≥slant 1.6 M ⊙ (the “retired A stars”) have not been overestimated in previous analyses. Using these new results for our sample of evolved stars, together with an updated sample of FGKM dwarfs, we confirm that giant planet occurrence increases with both stellar mass and metallicity up to 2.0 M ⊙. We show that the probability of formation of a giant planet is approximately a one-to-one function of the total amount of metals in the protoplanetary disk {M}\\star {10}[{Fe/{{H}}]}. This correlation provides additional support for the core accretion mechanism of planet formation.

Validation of electronic structure methods for isomerization reactions of large organic molecules.

PubMed

Luo, Sijie; Zhao, Yan; Truhlar, Donald G

2011-08-14

In this work the ISOL24 database of isomerization energies of large organic molecules presented by Huenerbein et al. [Phys. Chem. Chem. Phys., 2010, 12, 6940] is updated, resulting in the new benchmark database called ISOL24/11, and this database is used to test 50 electronic model chemistries. To accomplish the update, the very expensive and highly accurate CCSD(T)-F12a/aug-cc-pVDZ method is first exploited to investigate a six-reaction subset of the 24 reactions, and by comparison of various methods with the benchmark, MCQCISD-MPW is confirmed to be of high accuracy. The final ISOL24/11 database is composed of six reaction energies calculated by CCSD(T)-F12a/aug-cc-pVDZ and 18 calculated by MCQCISD-MPW. We then tested 40 single-component density functionals (both local and hybrid), eight doubly hybrid functionals, and two other methods against ISOL24/11. It is found that the SCS-MP3/CBS method, which is used as benchmark for the original ISOL24, has an MUE of 1.68 kcal mol(-1), which is close to or larger than some of the best tested DFT methods. Using the new benchmark, we find ωB97X-D and MC3MPWB to be the best single-component and doubly hybrid functionals respectively, with PBE0-D3 and MC3MPW performing almost as well. The best single-component density functionals without molecular mechanics dispersion-like terms are M08-SO, M08-HX, M05-2X, and M06-2X. The best single-component density functionals without Hartree-Fock exchange are M06-L-D3 when MM terms are included and M06-L when they are not.

Microbial Communities Model Parameter Calculation for TSPA/SR

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. Jolley

2001-07-16

This calculation has several purposes. First the calculation reduces the information contained in ''Committed Materials in Repository Drifts'' (BSC 2001a) to useable parameters required as input to MING V1.O (CRWMS M&O 1998, CSCI 30018 V1.O) for calculation of the effects of potential in-drift microbial communities as part of the microbial communities model. The calculation is intended to replace the parameters found in Attachment II of the current In-Drift Microbial Communities Model revision (CRWMS M&O 2000c) with the exception of Section 11-5.3. Second, this calculation provides the information necessary to supercede the following DTN: M09909SPAMING1.003 and replace it with a newmore » qualified dataset (see Table 6.2-1). The purpose of this calculation is to create the revised qualified parameter input for MING that will allow {Delta}G (Gibbs Free Energy) to be corrected for long-term changes to the temperature of the near-field environment. Calculated herein are the quadratic or second order regression relationships that are used in the energy limiting calculations to potential growth of microbial communities in the in-drift geochemical environment. Third, the calculation performs an impact review of a new DTN: M00012MAJIONIS.000 that is intended to replace the currently cited DTN: GS9809083 12322.008 for water chemistry data used in the current ''In-Drift Microbial Communities Model'' revision (CRWMS M&O 2000c). Finally, the calculation updates the material lifetimes reported on Table 32 in section 6.5.2.3 of the ''In-Drift Microbial Communities'' AMR (CRWMS M&O 2000c) based on the inputs reported in BSC (2001a). Changes include adding new specified materials and updating old materials information that has changed.« less

PCoM-DB Update: A Protein Co-Migration Database for Photosynthetic Organisms.

PubMed

Takabayashi, Atsushi; Takabayashi, Saeka; Takahashi, Kaori; Watanabe, Mai; Uchida, Hiroko; Murakami, Akio; Fujita, Tomomichi; Ikeuchi, Masahiko; Tanaka, Ayumi

2017-01-01

The identification of protein complexes is important for the understanding of protein structure and function and the regulation of cellular processes. We used blue-native PAGE and tandem mass spectrometry to identify protein complexes systematically, and built a web database, the protein co-migration database (PCoM-DB, http://pcomdb.lowtem.hokudai.ac.jp/proteins/top), to provide prediction tools for protein complexes. PCoM-DB provides migration profiles for any given protein of interest, and allows users to compare them with migration profiles of other proteins, showing the oligomeric states of proteins and thus identifying potential interaction partners. The initial version of PCoM-DB (launched in January 2013) included protein complex data for Synechocystis whole cells and Arabidopsis thaliana thylakoid membranes. Here we report PCoM-DB version 2.0, which includes new data sets and analytical tools. Additional data are included from whole cells of the pelagic marine picocyanobacterium Prochlorococcus marinus, the thermophilic cyanobacterium Thermosynechococcus elongatus, the unicellular green alga Chlamydomonas reinhardtii and the bryophyte Physcomitrella patens. The Arabidopsis protein data now include data for intact mitochondria, intact chloroplasts, chloroplast stroma and chloroplast envelopes. The new tools comprise a multiple-protein search form and a heat map viewer for protein migration profiles. Users can compare migration profiles of a protein of interest among different organelles or compare migration profiles among different proteins within the same sample. For Arabidopsis proteins, users can compare migration profiles of a protein of interest with putative homologous proteins from non-Arabidopsis organisms. The updated PCoM-DB will help researchers find novel protein complexes and estimate their evolutionary changes in the green lineage. © The Author 2017. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Convolutional Dictionary Learning: Acceleration and Convergence

NASA Astrophysics Data System (ADS)

Chun, Il Yong; Fessler, Jeffrey A.

2018-04-01

Convolutional dictionary learning (CDL or sparsifying CDL) has many applications in image processing and computer vision. There has been growing interest in developing efficient algorithms for CDL, mostly relying on the augmented Lagrangian (AL) method or the variant alternating direction method of multipliers (ADMM). When their parameters are properly tuned, AL methods have shown fast convergence in CDL. However, the parameter tuning process is not trivial due to its data dependence and, in practice, the convergence of AL methods depends on the AL parameters for nonconvex CDL problems. To moderate these problems, this paper proposes a new practically feasible and convergent Block Proximal Gradient method using a Majorizer (BPG-M) for CDL. The BPG-M-based CDL is investigated with different block updating schemes and majorization matrix designs, and further accelerated by incorporating some momentum coefficient formulas and restarting techniques. All of the methods investigated incorporate a boundary artifacts removal (or, more generally, sampling) operator in the learning model. Numerical experiments show that, without needing any parameter tuning process, the proposed BPG-M approach converges more stably to desirable solutions of lower objective values than the existing state-of-the-art ADMM algorithm and its memory-efficient variant do. Compared to the ADMM approaches, the BPG-M method using a multi-block updating scheme is particularly useful in single-threaded CDL algorithm handling large datasets, due to its lower memory requirement and no polynomial computational complexity. Image denoising experiments show that, for relatively strong additive white Gaussian noise, the filters learned by BPG-M-based CDL outperform those trained by the ADMM approach.

Forecasting the (un)productivity of the 2014 M 6.0 South Napa aftershock sequence

USGS Publications Warehouse

Llenos, Andrea L.; Michael, Andrew J.

2017-01-01

The 24 August 2014 Mw 6.0 South Napa mainshock produced fewer aftershocks than expected for a California earthquake of its magnitude. In the first 4.5 days, only 59 M≥1.8 aftershocks occurred, the largest of which was an M 3.9 that happened a little over two days after the mainshock. We investigate the aftershock productivity of the South Napa sequence and compare it with other M≥5.5 California strike‐slip mainshock–aftershock sequences. While the productivity of the South Napa sequence is among the lowest, northern California mainshocks generally have fewer aftershocks than mainshocks further south, although the productivities vary widely in both regions. An epidemic‐type aftershock sequence (ETAS) model (Ogata, 1988) fit to Napa seismicity from 1980 to 23 August 2014 fits the sequence well and suggests that low‐productivity sequences are typical of this area. Utilizing regional variations in productivity could improve operational earthquake forecasting (OEF) by improving the model used immediately after the mainshock. We show this by comparing the daily rate of M≥2 aftershocks to forecasts made with the generic California model (Reasenberg and Jones, 1989; hereafter, RJ89), RJ89 models with productivity updated daily, a generic California ETAS model, an ETAS model based on premainshock seismicity, and ETAS models updated daily following the mainshock. RJ89 models for which only the productivity is updated provide better forecasts than the generic RJ89 California model, and the Napa‐specific ETAS models forecast the aftershock rates more accurately than either generic model. Therefore, forecasts that use localized initial parameters and that rapidly update the productivity may be better for OEF than using a generic model and/or updating all parameters.

Updated Prognostic Model for Predicting Overall Survival in First-Line Chemotherapy for Patients With Metastatic Castration-Resistant Prostate Cancer

PubMed Central

Halabi, Susan; Lin, Chen-Yen; Kelly, W. Kevin; Fizazi, Karim S.; Moul, Judd W.; Kaplan, Ellen B.; Morris, Michael J.; Small, Eric J.

2014-01-01

Purpose Prognostic models for overall survival (OS) for patients with metastatic castration-resistant prostate cancer (mCRPC) are dated and do not reflect significant advances in treatment options available for these patients. This work developed and validated an updated prognostic model to predict OS in patients receiving first-line chemotherapy. Methods Data from a phase III trial of 1,050 patients with mCRPC were used (Cancer and Leukemia Group B CALGB-90401 [Alliance]). The data were randomly split into training and testing sets. A separate phase III trial served as an independent validation set. Adaptive least absolute shrinkage and selection operator selected eight factors prognostic for OS. A predictive score was computed from the regression coefficients and used to classify patients into low- and high-risk groups. The model was assessed for its predictive accuracy using the time-dependent area under the curve (tAUC). Results The model included Eastern Cooperative Oncology Group performance status, disease site, lactate dehydrogenase, opioid analgesic use, albumin, hemoglobin, prostate-specific antigen, and alkaline phosphatase. Median OS values in the high- and low-risk groups, respectively, in the testing set were 17 and 30 months (hazard ratio [HR], 2.2; P < .001); in the validation set they were 14 and 26 months (HR, 2.9; P < .001). The tAUCs were 0.73 (95% CI, 0.70 to 0.73) and 0.76 (95% CI, 0.72 to 0.76) in the testing and validation sets, respectively. Conclusion An updated prognostic model for OS in patients with mCRPC receiving first-line chemotherapy was developed and validated on an external set. This model can be used to predict OS, as well as to better select patients to participate in trials on the basis of their prognosis. PMID:24449231

Orientation Modeling for Amateur Cameras by Matching Image Line Features and Building Vector Data

NASA Astrophysics Data System (ADS)

Hung, C. H.; Chang, W. C.; Chen, L. C.

2016-06-01

With the popularity of geospatial applications, database updating is getting important due to the environmental changes over time. Imagery provides a lower cost and efficient way to update the database. Three dimensional objects can be measured by space intersection using conjugate image points and orientation parameters of cameras. However, precise orientation parameters of light amateur cameras are not always available due to their costliness and heaviness of precision GPS and IMU. To automatize data updating, the correspondence of object vector data and image may be built to improve the accuracy of direct georeferencing. This study contains four major parts, (1) back-projection of object vector data, (2) extraction of image feature lines, (3) object-image feature line matching, and (4) line-based orientation modeling. In order to construct the correspondence of features between an image and a building model, the building vector features were back-projected onto the image using the initial camera orientation from GPS and IMU. Image line features were extracted from the imagery. Afterwards, the matching procedure was done by assessing the similarity between the extracted image features and the back-projected ones. Then, the fourth part utilized line features in orientation modeling. The line-based orientation modeling was performed by the integration of line parametric equations into collinearity condition equations. The experiment data included images with 0.06 m resolution acquired by Canon EOS Mark 5D II camera on a Microdrones MD4-1000 UAV. Experimental results indicate that 2.1 pixel accuracy may be reached, which is equivalent to 0.12 m in the object space.

Update: Mechanisms underlying N6-methyladenosine modification of eukaryotic mRNA

PubMed Central

Wang, Yang; Zhao, Jing Crystal

2016-01-01

Summary Eukaryotic messenger RNA (mRNA) undergoes chemical modification both at the 5′cap [1, 2] and internally [3–14]. Among internal modifications, m6A, by far the most abundant, is present in all eukaryotes examined, including mammals [3–6], flies [15], plants [16, 17] and yeast [18, 19]. m6A modification plays an essential role in diverse biological processes. Over the past few years, our knowledge relevant to establishment and function of this modification has grown rapidly. This review focuses on technologies that have facilitated m6A detection in mRNAs, identification of m6A methylation enzymes and binding proteins, and potential functions of the modification at the molecular level. Regarding m6A function at cellular or organismal levels or in disease, please refer to other recent reviews [20–23]. PMID:27793360

An update on minding the gap in cancer.

PubMed

Mesnil, Marc; Aasen, Trond; Boucher, Jonathan; Chépied, Amandine; Cronier, Laurent; Defamie, Norah; Kameritsch, Petra; Laird, Dale W; Lampe, Paul D; Lathia, Justin D; Leithe, Edward; Mehta, Parmender P; Monvoisin, Arnaud; Pogoda, Kristin; Sin, Wun-Chey; Tabernero, Arantxa; Yamasaki, Hiroshi; Yeh, Elizabeth S; Dagli, Maria Lucia Zaidan; Naus, Christian C

2018-01-01

This article is a report of the "International Colloquium on Gap junctions: 50Years of Impact on Cancer" that was held 8-9 September 2016, at the Amphitheater "Pôle Biologie Santé" of the University of Poitiers (Poitiers, France). The colloquium was organized by M Mesnil (Université de Poitiers, Poitiers, France) and C Naus (University of British Columbia, Vancouver, Canada) to celebrate the 50th anniversary of the seminal work published in 1966 by Loewenstein and Kanno [Intercellular communication and the control of tissue growth: lack of communication between cancer cells, Nature, 116 (1966) 1248-1249] which initiated studies on the involvement of gap junctions in carcinogenesis. During the colloquium, 15 participants presented reviews or research updates in the field which are summarized below. Copyright © 2017 Elsevier B.V. All rights reserved.

The Next-Generation Infrared Space Mission Spica: Project Updates

NASA Astrophysics Data System (ADS)

Nakagawa, Takao; Shibai, Hiroshi; Kaneda, Hidehiro; Kohno, Kotaro; Matsuhara, Hideo; Ogawa, Hiroyuki; Onaka, Takashi; Roelfsema, Peter; SPICA Team

2017-03-01

We present project updates of the next-generation infrared space mission SPICA (Space Infrared Telescope for Cosmology and Astrophysics) as of November 2015. SPICA is optimized for mid- and far-infrared astronomy with unprecedented sensitivity, which will be achieved with a cryogenically cooled (below 8 K), large (2.5~m) telescope. SPICA is expected to address a number of key questions in various fields of astrophysics, ranging from studies of the star-formation history in the universe to the formation and evolution of planetary systems. The international collaboration framework of SPICA has been revisited. SPICA under the new framework passed the Mission Definition Review by JAXA in 2015. A proposal under the new framework to ESA is being prepared. The target launch year in the new framework is 2027/28.

Learning Rate Updating Methods Applied to Adaptive Fuzzy Equalizers for Broadband Power Line Communications

NASA Astrophysics Data System (ADS)

Ribeiro, Moisés V.

2004-12-01

This paper introduces adaptive fuzzy equalizers with variable step size for broadband power line (PL) communications. Based on delta-bar-delta and local Lipschitz estimation updating rules, feedforward, and decision feedback approaches, we propose singleton and nonsingleton fuzzy equalizers with variable step size to cope with the intersymbol interference (ISI) effects of PL channels and the hardness of the impulse noises generated by appliances and nonlinear loads connected to low-voltage power grids. The computed results show that the convergence rates of the proposed equalizers are higher than the ones attained by the traditional adaptive fuzzy equalizers introduced by J. M. Mendel and his students. Additionally, some interesting BER curves reveal that the proposed techniques are efficient for mitigating the above-mentioned impairments.

NONCODE v2.0: decoding the non-coding.

PubMed

He, Shunmin; Liu, Changning; Skogerbø, Geir; Zhao, Haitao; Wang, Jie; Liu, Tao; Bai, Baoyan; Zhao, Yi; Chen, Runsheng

2008-01-01

The NONCODE database is an integrated knowledge database designed for the analysis of non-coding RNAs (ncRNAs). Since NONCODE was first released 3 years ago, the number of known ncRNAs has grown rapidly, and there is growing recognition that ncRNAs play important regulatory roles in most organisms. In the updated version of NONCODE (NONCODE v2.0), the number of collected ncRNAs has reached 206 226, including a wide range of microRNAs, Piwi-interacting RNAs and mRNA-like ncRNAs. The improvements brought to the database include not only new and updated ncRNA data sets, but also an incorporation of BLAST alignment search service and access through our custom UCSC Genome Browser. NONCODE can be found under http://www.noncode.org or http://noncode.bioinfo.org.cn.

Comparative regional-scale soil salinity assessment with near-ground apparent electrical conductivity and remote sensing canopy reflectance

USDA-ARS?s Scientific Manuscript database

Soil salinity is recognized worldwide as a major threat to agriculture, particularly in arid and semi-arid regions. Farmers and decision makers need updated and accurate maps of salinity in agronomically and environmentally relevant ranges (i.e., <20 dS m/1, when salinity is measured as electrical...

Forests of east Texas, 2013

Treesearch

K.J.W. Dooley; T.J. Brandeis

2014-01-01

This resource update provides an overview of forest resources in east Texas based on an inventory conducted by the U.S. Forest Service, Forest Inventory and Analysis (FIA) program at the Southern Research Station in cooperation with the Texas A&M Forest Service. Forest resource estimates are based on field data collected using the FIA annualized sample design and...

75 FR 69472 - Preparations for December UN Meetings on the Globally Harmonized System of Classification and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... 30, 2010, from 1-3 p.m., in Washington, DC. ADDRESSES: The location for the public meeting is as..., physical, and environmental effects. It also provides harmonized communication elements, including labels... explanatory text. The UNSCEGHS is responsible for maintaining and updating the GHS. The U.S has been an active...

Forests of east Texas, 2016

Treesearch

Kerry Dooley

2018-01-01

This resource update provides an overview of forest resources in east Texas based on an inventory conducted by the U.S. Forest Service, Forest Inventory and Analysis (FIA) program at the Southern Research Station (SRS) in cooperation with Texas A&M Forest Service. The 254 counties of Texas are consolidated into seven FIA survey units—Southeast (unit 1),...

AR Alternative Splicing and Prostate Cancer Progression

DTIC Science & Technology

2012-07-01

database (ARDB): update. Human Mutation 23 527–533. (doi:10.1002/ humu .20044) Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Kong X, Melamed J, Tepper...doi:10.1002/ humu .21138) Matias PM, Donner P, Coelho R, Thomaz M, Peixoto C, Macedo S, Otto N, Joschko S, Scholz P, Wegg A et al. 2000 Structural

(Update) HIV Conference to Be Held on February 25 at NCI at Frederick | Poster

Cancer.gov

By Anne Arthur, Guest Writer The HIV Drug Resistance Program (HIV DRP), Center for Cancer Research (CCR), will hold a conference on “Host Factors and Cofactors in HIV Infection” at the National Cancer Institute (NCI) campus in Frederick, Md., on Feb. 25, from 1:00 to 5:35 p.m.

75 FR 5091 - Office of the Director, National Institutes of Health; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-01

... available. Individuals who plan to attend and need special assistance, such as sign language interpretation.... to 5 p.m. Agenda: The theme of the meeting will be ``HIV/AIDS and Aging.'' The meeting will address... antiretroviral therapies in HIV-infected individuals; and premature aging in HIV-infected individuals. An update...

Forests of East Texas, 2014

Treesearch

Thomas J. Brandeis

2015-01-01

This resource update provides an overview of forest resources in east Texas derived from an inventory conducted by the U.S. Forest Service, Forest Inventory and Analysis (FIA) Program at the Southern Research Station in cooperation with the Texas A&M Forest Service. These estimates are based on field data collected using the FIA annualized sample design and are...

The U.S. Salinity Laboratory (USDA-ARS) guidelines for assessing multi-scale soil salinity with proximal and remote sensing

USDA-ARS?s Scientific Manuscript database

Soil salinity is a major threat to sustainable agriculture, especially in arid and semi-arid regions. Updated and accurate inventories of salinity in agronomically and environmentally relevant ranges (i.e., <20 dS/m, when salinity is measured as electrical conductivity of the saturation extract, ECe...

Sustained mahogany (Swietenia macrophylla) plantation heartwood increment.

Treesearch

Frank H. Wadsworth; Edgardo. Gonzalez

2008-01-01

In a search for an increment-based rotation for plantation mahogany(Swietenia macrophylla King), heartwood volume per tree was regressed on DBH (trunk diameter outside bark at 1.4 m above the ground) and merchantable height measurements. We updated a previous study [Wadsworth, F.H., González González, E., Figuera Colón, J.C., Lugo P...

78 FR 70076 - Large Scale Networking (LSN)-Middleware and Grid Interagency Coordination (MAGIC) Team

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-22

... Coordination (MAGIC) Team AGENCY: The Networking and Information Technology Research and Development (NITRD... MAGIC Team meetings are held on the first Wednesday of each month, 2:00-4:00 p.m., at the National... for each meeting. Please reference the MAGIC Team Web site for updates. Magic Web site: The agendas...

Forests of east Texas, 2015

Treesearch

Kerry J.W. Dooley

2017-01-01

This resource update provides an overview of forest resources in east Texas based on an inventory conducted by the U.S. Forest Service, Forest Inventory and Analysis (FIA) program at the Southern Research Station (SRS) in cooperation with Texas A&M Forest Service. The 254 counties of Texas are consolidated into seven FIA survey units—Southeast (unit 1),...

In the Era of Limits: A Galveston District History Update, 1976-1986

DTIC Science & Technology

1990-08-01

Sierra Club vs. Marsh. 34Maass, Muddy Waters, p. 23; Thomas M. Clement, Jr., Glenn Lopez, and Pamela T. Mountain , "Engineering a Victory for Our...great land, I’m sure. It’s got ever-thin’ a man might want-free land, free cattle, beautiful rivers, and mountains too, I hear, in the west. But...meteorologist compared it to "a gorilla with a machine gun. It goes where it wants to.൨ As sus- tained winds increased to 7 4 miles per hour, the

Larva and pupa of Megatoma (s. str.) undata (Linnaeus, 1758) with remarks on biology and economic importance (Coleoptera, Dermestidae).

PubMed

Kadej, Marcin

2017-01-01

An updated description of the final larval instar and pupa of Megatoma (s. str.) undata (Linnaeus, 1758) (Coleoptera: Dermestidae) is presented. Several morphological characteristics of M. undata larvae are documented and discussed: antenna, epipharynx, mandibula, maxilla, ligula with labial palpi, hastisetae, terga, and condition of the antecostal suture. The paper is fully illustrated and includes some important additions to extend notes on this species available in the references. Summarised data about biology, economic importance, and distribution of M. undata are also provided.

Predictive monitoring of actions, EEG recordings in virtual reality.

PubMed

Ozkan, Duru G; Pezzetta, Rachele

2018-04-01

Error-related negativity (ERN) is a signal that is associated with error detection. Joch and colleagues (Joch M, Hegele M, Maurer H, Müller H, Maurer LK. J Neurophysiol 118: 486-495, 2017) successfully separated the ERN as a response to online prediction error from feedback updates. We discuss the role of ERN in action and suggest insights from virtual reality techniques; we consider the potential benefit of self-evaluation in determining the mechanisms of ERN amplitude; finally, we review the oscillatory activity that has been claimed to accompany ERN.

Munitions Classification Library Update and Expansion Data Collection Report: Camp Lejeune and Eglin

DTIC Science & Technology

2015-10-09

Motor 4.5-in T160ES HE R N N N N W without Motor Rocket Motor R N N N N W 66mm M72A1 R Y Y N N U with Coupler and Motor ...66mm M74 R N Y N N W with Motor 3.5-in M30A1 R Y Y N N W WP Smoke with M405 Dummy Fuze and Motor Rocket Motor R Y N N N W 3.5-in M30A1 R N Y N N...N U/P with Motor without Fins 2.36-in M6 R Y Y N N U/P with Motor with Fins Rocket Motor R Y Y N N U/P 2.36-in M6 R N N N N U/P Rifle

Land cover classification of VHR airborne images for citrus grove identification

NASA Astrophysics Data System (ADS)

Amorós López, J.; Izquierdo Verdiguier, E.; Gómez Chova, L.; Muñoz Marí, J.; Rodríguez Barreiro, J. Z.; Camps Valls, G.; Calpe Maravilla, J.

Managing land resources using remote sensing techniques is becoming a common practice. However, data analysis procedures should satisfy the high accuracy levels demanded by users (public or private companies and governments) in order to be extensively used. This paper presents a multi-stage classification scheme to update the citrus Geographical Information System (GIS) of the Comunidad Valenciana region (Spain). Spain is the first citrus fruit producer in Europe and the fourth in the world. In particular, citrus fruits represent 67% of the agricultural production in this region, with a total production of 4.24 million tons (campaign 2006-2007). The citrus GIS inventory, created in 2001, needs to be regularly updated in order to monitor changes quickly enough, and allow appropriate policy making and citrus production forecasting. Automatic methods are proposed in this work to facilitate this update, whose processing scheme is summarized as follows. First, an object-oriented feature extraction process is carried out for each cadastral parcel from very high spatial resolution aerial images (0.5 m). Next, several automatic classifiers (decision trees, artificial neural networks, and support vector machines) are trained and combined to improve the final classification accuracy. Finally, the citrus GIS is automatically updated if a high enough level of confidence, based on the agreement between classifiers, is achieved. This is the case for 85% of the parcels and accuracy results exceed 94%. The remaining parcels are classified by expert photo-interpreters in order to guarantee the high accuracy demanded by policy makers.

Is 30-second update fast enough for convection-resolving data assimilation?

NASA Astrophysics Data System (ADS)

Miyoshi, Takemasa; Ruiz, Juan; Lien, Guo-Yuan; Teramura, Toshiki; Kondo, Keiichi; Maejima, Yasumitsu; Honda, Takumi; Otsuka, Shigenori

2017-04-01

For local severe weather forecasting at 100-m resolution with 30-minute lead time, we have been working on the "Big Data Assimilation" (BDA) effort for super-rapid 30-second cycle of an ensemble Kalman filter. We have presented two papers with the concept and case studies (Miyoshi et al. 2016, BAMS; Proceedings of the IEEE). We focus on the non-Gaussian PDF in this study. We were hoping that we could assume the Gaussian error distribution in 30-second forecasts before strong nonlinear dynamics distort the error distribution for rapidly-changing convective storms. However, using 1000 ensemble members, the reduced-resolution version of the BDA system at 1-km grid spacing with 30-second updates showed ubiquity of highly non-Gaussian PDF. Although our results so far with multiple case studies were quite successful, this gives us a doubt about our Gaussian assumption even if the data assimilation interval is short enough compared with the system's chaotic time scale. We therefore pose a question if the 30-second update is fast enough for convection-resolving data assimilation under the Gaussian assumption. To answer this question, we aim to gain combined knowledge from BDA case studies, 1000-member experiments, 30-second breeding experiments, and toy-model experiments with dense and frequent observations. In this presentation, we will show the most up-to-date results of the BDA research, and will discuss about the question if the 30-second update is fast enough for convective-scale data assimilation.

Refinement of late-Early and Middle Miocene diatom biostratigraphy for the east coast of the United States

USGS Publications Warehouse

Barron, John A.; Browning, James; Sugarman, Peter; Miller, Kenneth G.

2013-01-01

Integrated Ocean Drilling Program (IODP) Expedition 313 continuously cored Lower to Middle Miocene sequences at three continental shelf sites off New Jersey, USA. The most seaward of these, Site M29, contains a well-preserved Early and Middle Miocene succession of planktonic diatoms that have been independently correlated with the geomagnetic polarity time scale derived in studies from the equatorial and North Pacific. Shallow water diatoms (species of Delphineis, Rhaphoneis, and Sceptroneis) dominate in onshore sequences in Maryland and Virginia, forming the basis for the East Coast Diatom Zones (ECDZ). Integrated study of both planktonic and shallow water diatoms in Hole M29A as well as in onshore sequences in Maryland (the Baltimore Gas and Electric Company well) and Delaware (the Ocean Drilling Program Bethany Beach corehole) allows the refinement of ECDZ zones into a high-resolution biochronology that can be successfully applied in both onshore and offshore regions of the East Coast of the United States. Strontium isotope stratigraphy supports the diatom biochronology, although for much of the Middle Miocene it suggests ages that are on average 0.4 m.y. older. The ECDZ zonal definitions are updated to include evolutionary events of Delphineis species, and regional occurrences of important planktonic diatom marker taxa are included. Updated taxonomy, reference to published figures, and photographic images are provided that will aid in the application of this diatom biostratigraphy.

Left-right asymmetry in the light of TOR: An update on what we know so far.

PubMed

Casar Tena, Teresa; Burkhalter, Martin D; Philipp, Melanie

2015-09-01

The internal left-right (LR) asymmetry is a characteristic that exists throughout the animal kingdom from roundworms over flies and fish to mammals. Cilia, which are antenna-like structures protruding into the extracellular space, are involved in establishing LR asymmetry during early development. Humans who suffer from dysfunctional cilia often develop conditions such as heterotaxy, where internal organs appear to be placed randomly. As a consequence to this failure in asymmetry development, serious complications such as congenital heart defects (CHD) occur. The mammalian (or mechanistic) target of rapamycin (mTOR) pathway has recently emerged as an important regulator regarding symmetry breaking. The mTOR pathway governs fundamental processes such as protein translation or metabolism. Its activity can be transduced by two complexes, which are called TORC1 and TORC2, respectively. So far, only TORC1 has been implicated with asymmetry development and appears to require very precise regulation. A number of recent papers provided evidence that dysregulated TORC1 results in alterations of motile cilia and asymmetry defects. In here, we give an update on what we know so far of mTORC1 in LR asymmetry development. © 2015 The Authors. Biology of the Cell published by John Wiley & Sons Ltd on behalf of Société Française des Microscopies and Société de Biologie Cellulaire de France.

Attenuating fearful memories: effect of cued extinction on intrusions.

PubMed

Marks, Elizabeth H; Zoellner, Lori A

2014-12-01

Exposure-based therapies for posttraumatic stress disorder are thought to reduce intrusive memories through extinction processes. Methods that enhance extinction may translate to improved treatment. Rat research suggests retrieving a memory via a conditioned stimulus (CS) cue, and then modifying the retrieved memory within a specific reconsolidation window may enhance extinction. In humans, studies (e.g., Kindt & Soeter, 2013; Schiller et al., 2010) using basic learning paradigms show discrepant findings. Using a distressing film paradigm, participants (N = 148) completed fear acquisition and extinction. At extinction, they were randomized to 1 of 3 groups: CS cue within reconsolidation window, CS cue outside window, or non-CS cue within window. Intrusions were assessed 24 hr after extinction. Participants receiving the CS cue and completing extinction within the reconsolidation window had more intrusions (M = 2.40, SD = 2.54) than those cued outside (M = 1.65, SD = 1.70) or those receiving a non-CS cue (M = 1.24, SD = 1.26), F(2, 145) = 4.52, p = .01, d = 0.55. Consistent with the reconsolidation hypothesis, presenting a CS cue does appear to activate a specific period of time during which a memory can be updated. However, the CS cue caused increased, rather than decreased, frequency of intrusions. Understanding parameters of preextinction cueing may help us better understand reconsolidation as a potential memory updating mechanism.

Do your extractable TPH concentrations represent dissolved petroleum? An update on applied research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zemo, D.A.

1997-12-31

Elevated concentrations of {open_quotes}dissolved-phase{close_quotes} extractable total petroleum hydrocarbons (TPH) in groundwater samples can be a significant impediment to site closure in states that regulate groundwater using TPH criteria. These analytical results are inconsistent with petroleum chemistry because of the relatively low water solubility of petroleum products. This paper presents an update of our research into the source of medium- to high-boiling TPH detections in groundwater samples and application of the results to multiple projects. This work follows from a 1995 publication in which positive interferences to the Method 8015M (GC-FID) TPH measurement by soluble, non-petroleum hydrocarbons resulting from intrinsic bioremediationmore » or non-dissolved petroleum adhered to particulates was described. The 1995 paper was largely theoretical and focused on one case study. Since 1995, we have evaluated the source of TPH detections in groundwater at numerous petroleum sites and have demonstrated the significance of interferences to the Method 8015M measurement to the California regulatory community. Our work has shown conclusively that elevated concentrations of extractable TPH are not representative of dissolved petroleum constituents. We have shown that a sample cleanup prior to analysis using silica gel cleanup (to remove polar non-petroleum hydrocarbons) and/or laboratory filtration (to reduce petroleum-affected particulates) is required to overcome the false positives caused by interferences to the Method 8015M measurement.« less

Technical Note: spektr 3.0-A computational tool for x-ray spectrum modeling and analysis.

PubMed

Punnoose, J; Xu, J; Sisniega, A; Zbijewski, W; Siewerdsen, J H

2016-08-01

A computational toolkit (spektr 3.0) has been developed to calculate x-ray spectra based on the tungsten anode spectral model using interpolating cubic splines (TASMICS) algorithm, updating previous work based on the tungsten anode spectral model using interpolating polynomials (TASMIP) spectral model. The toolkit includes a matlab (The Mathworks, Natick, MA) function library and improved user interface (UI) along with an optimization algorithm to match calculated beam quality with measurements. The spektr code generates x-ray spectra (photons/mm(2)/mAs at 100 cm from the source) using TASMICS as default (with TASMIP as an option) in 1 keV energy bins over beam energies 20-150 kV, extensible to 640 kV using the TASMICS spectra. An optimization tool was implemented to compute the added filtration (Al and W) that provides a best match between calculated and measured x-ray tube output (mGy/mAs or mR/mAs) for individual x-ray tubes that may differ from that assumed in TASMICS or TASMIP and to account for factors such as anode angle. The median percent difference in photon counts for a TASMICS and TASMIP spectrum was 4.15% for tube potentials in the range 30-140 kV with the largest percentage difference arising in the low and high energy bins due to measurement errors in the empirically based TASMIP model and inaccurate polynomial fitting. The optimization tool reported a close agreement between measured and calculated spectra with a Pearson coefficient of 0.98. The computational toolkit, spektr, has been updated to version 3.0, validated against measurements and existing models, and made available as open source code. Video tutorials for the spektr function library, UI, and optimization tool are available.

Aging of theory of mind: the influence of educational level and cognitive processing.

PubMed

Li, Xiaoming; Wang, Kai; Wang, Fan; Tao, Qian; Xie, Yu; Cheng, Qi

2013-01-01

Previous studies of theory of mind (ToM) in old age have provided mixed results. We predicted that educational level and cognitive processing are two factors influencing the pattern of the aging of ToM. To test this hypothesis, a younger group who received higher education (mean age 20.46 years), an older group with an education level equal to that of the young group (mean age 76.29 years), and an older group with less education (mean age 73.52 years) were recruited. ToM tasks included the following tests: the second-order false-belief task, the faux-pas task, the eyes test, and tests of fundamental aspects of cognitive function that included two background tests (memory span and processing speed) and three subcomponents of executive function (inhibition, updating, and shifting). We found that the younger group and the older group with equally high education outperformed the older group with less education in false-belief and faux-pas tasks. However, there was no significant difference between the two former groups. The three groups of participants performed equivalently in the eyes test as well as in control tasks (false-belief control question, faux-pas control question, faux-pas control story, and Eyes Test control task). The younger group outperformed the other two groups in the cognitive processing tasks. Mediation analyses showed that difficulties in inhibition, memory span, and processing speed mediated the age differences in false-belief reasoning. Also, the variables of inhibition, updating, memory span, and processing speed mediated age-related variance in faux-pas. Discussion focused on the links between ToM aging, educational level, and cognitive processing. Supported by Chinese National Natural Science Foundation (number: 30870766) and Anhui Province Natural Science Foundation (number: 11040606M166).

Clinical trial considerations on male contraception and collection of pregnancy information from female partner: update.

PubMed

Banholzer, Maria Longauer; Wandel, Christoph; Barrow, Paul; Mannino, Marie; Schmitt, Georg; Guérard, Melanie; Müller, Lutz; Greig, Gerard; Amemiya, Kenjie; Peck, Richard; Singer, Thomas; Doessegger, Lucette

2016-12-01

This is an update to our 2012 publication on clinical trial considerations on male contraception and collection of pregnancy information from female partner, after critical review of recent (draft) guidances released by the International Council for Harmonisation [ICH] the Clinical Trial Facilitation Group [CTFG] and the US Food & Drug Administration [FDA]. Relevant aspects of the new guidance documents are discussed in the context of male contraception and pregnancy reporting from female partner in clinical trials and the approach is updated accordingly. Genotoxicity The concept of a threshold is introduced using acceptable daily intake/permissible daily exposure to define genotoxicity requirements, hence highly effective contraception in order to avoid conception. The duration for highly effective contraception has been extended from 74 to 90 days from the end of relevant systemic exposure. Teratogenicity Pharmacokinetic considerations to estimate safety margins have been contextualized with regard to over- and underestimation of the risk of teratogenicity transmitted by a vaginal dose. The duration of male contraception after the last dose takes into account the end of relevant systemic exposure if measured, or a default period of five half-lives after last dose for small molecules and two half-lives for immunoglobulins (mAbs). Measures to prevent exposure of the conceptus via a vaginal dose apply to reproductively competent or vasectomized men, unless measurements fail to detect the compound in seminal fluid. Critical review of new guidance documents provides a comparison across approaches and resulted in an update of our previous publication. Separate algorithms for small molecules and monoclonal antibodies are proposed to guide the recommendations for contraception for male trial participants and pregnancy reporting from female partners. No male contraception is required if the dose is below a defined threshold for genotoxic concern applicable to small molecules. For men treated with teratogenic mAbs, condom use to prevent exposure of a potentially pregnant partner is unlikely to be recommended because of the minimal female exposure anticipated following a vaginal dose. The proposed safety margins for teratogenicity may evolve with further knowledge.

Quickly updatable hologram images with high performance photorefractive polymer composites

NASA Astrophysics Data System (ADS)

Tsutsumi, Naoto; Kinashi, Kenji; Nonomura, Asato; Sakai, Wataru

2012-02-01

We present here quickly updatable hologram images using high performance photorefractive (PR) polymer composite based on poly(N-vinyl carbazole) (PVCz). PVCz is one of the pioneer materials for photoconductive polymer. PVCz/7- DCST/CzEPA/TNF (44/35/20/1 by wt) gives high diffraction efficiency of 68 % at E = 45 V/μm with fast response speed. Response speed of optical diffraction is the key parameter for real-time 3D holographic display. Key parameter for obtaining quickly updatable hologram images is to control the glass transition temperature lower enough to enhance chromophore orientation. Object image of the reflected coin surface recorded with reference beam at 532 nm (green beam) in the PR polymer composite is simultaneously reconstructed using a red probe beam at 642 nm. Instead of using coin object, object image produced by a computer was displayed on a spatial light modulator (SLM) is used as an object for hologram. Reflected object beam from a SLM interfered with reference beam on PR polymer composite to record a hologram and simultaneously reconstructed by a red probe beam. Movie produced in a computer was recorded as a realtime hologram in the PR polymer composite and simultaneously clearly reconstructed with a video rate.

miRWalk--database: prediction of possible miRNA binding sites by "walking" the genes of three genomes.

PubMed

Dweep, Harsh; Sticht, Carsten; Pandey, Priyanka; Gretz, Norbert

2011-10-01

MicroRNAs are small, non-coding RNA molecules that can complementarily bind to the mRNA 3'-UTR region to regulate the gene expression by transcriptional repression or induction of mRNA degradation. Increasing evidence suggests a new mechanism by which miRNAs may regulate target gene expression by binding in promoter and amino acid coding regions. Most of the existing databases on miRNAs are restricted to mRNA 3'-UTR region. To address this issue, we present miRWalk, a comprehensive database on miRNAs, which hosts predicted as well as validated miRNA binding sites, information on all known genes of human, mouse and rat. All mRNAs, mitochondrial genes and 10 kb upstream flanking regions of all known genes of human, mouse and rat were analyzed by using a newly developed algorithm named 'miRWalk' as well as with eight already established programs for putative miRNA binding sites. An automated and extensive text-mining search was performed on PubMed database to extract validated information on miRNAs. Combined information was put into a MySQL database. miRWalk presents predicted and validated information on miRNA-target interaction. Such a resource enables researchers to validate new targets of miRNA not only on 3'-UTR, but also on the other regions of all known genes. The 'Validated Target module' is updated every month and the 'Predicted Target module' is updated every 6 months. miRWalk is freely available at http://mirwalk.uni-hd.de/. Copyright © 2011 Elsevier Inc. All rights reserved.

Update on Aire and thymic negative selection.

PubMed

Passos, Geraldo A; Speck-Hernandez, Cesar A; Assis, Amanda F; Mendes-da-Cruz, Daniella A

2018-01-01

Twenty years ago, the autoimmune regulator (Aire) gene was associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, and was cloned and sequenced. Its importance goes beyond its abstract link with human autoimmune disease. Aire identification opened new perspectives to better understand the molecular basis of central tolerance and self-non-self distinction, the main properties of the immune system. Since 1997, a growing number of immunologists and molecular geneticists have made important discoveries about the function of Aire, which is essentially a pleiotropic gene. Aire is one of the functional markers in medullary thymic epithelial cells (mTECs), controlling their differentiation and expression of peripheral tissue antigens (PTAs), mTEC-thymocyte adhesion and the expression of microRNAs, among other functions. With Aire, the immunological tolerance became even more apparent from the molecular genetics point of view. Currently, mTECs represent the most unusual cells because they express almost the entire functional genome but still maintain their identity. Due to the enormous diversity of PTAs, this uncommon gene expression pattern was termed promiscuous gene expression, the interpretation of which is essentially immunological - i.e. it is related to self-representation in the thymus. Therefore, this knowledge is strongly linked to the negative selection of autoreactive thymocytes. In this update, we focus on the most relevant results of Aire as a transcriptional and post-transcriptional controller of PTAs in mTECs, its mechanism of action, and its influence on the negative selection of autoreactive thymocytes as the bases of the induction of central tolerance and prevention of autoimmune diseases. © 2017 John Wiley & Sons Ltd.

Assimilating every-30-second 100-m-mesh radar observations for convective weather: implications to non-Gaussian PDF

NASA Astrophysics Data System (ADS)

Miyoshi, T.; Teramura, T.; Ruiz, J.; Kondo, K.; Lien, G. Y.

2016-12-01

Convective weather is known to be highly nonlinear and chaotic, and it is hard to predict their location and timing precisely. Our Big Data Assimilation (BDA) effort has been exploring to use dense and frequent observations to avoid non-Gaussian probability density function (PDF) and to apply an ensemble Kalman filter under the Gaussian error assumption. The phased array weather radar (PAWR) can observe a dense three-dimensional volume scan with 100-m range resolution and 100 elevation angles in only 30 seconds. The BDA system assimilates the PAWR reflectivity and Doppler velocity observations every 30 seconds into 100 ensemble members of storm-scale numerical weather prediction (NWP) model at 100-m grid spacing. The 30-second-update, 100-m-mesh BDA system has been quite successful in multiple case studies of local severe rainfall events. However, with 1000 ensemble members, the reduced-resolution BDA system at 1-km grid spacing showed significant non-Gaussian PDF with every-30-second updates. With a 10240-member ensemble Kalman filter with a global NWP model at 112-km grid spacing, we found roughly 1000 members satisfactory to capture the non-Gaussian error structures. With these in mind, we explore how the density of observations in space and time affects the non-Gaussianity in an ensemble Kalman filter with a simple toy model. In this presentation, we will present the most up-to-date results of the BDA research, as well as the investigation with the toy model on the non-Gaussianity with dense and frequent observations.

Stellar Parameters for Trappist-1

NASA Astrophysics Data System (ADS)

Van Grootel, Valérie; Fernandes, Catarina S.; Gillon, Michael; Jehin, Emmanuel; Manfroid, Jean; Scuflaire, Richard; Burgasser, Adam J.; Barkaoui, Khalid; Benkhaldoun, Zouhair; Burdanov, Artem; Delrez, Laetitia; Demory, Brice-Olivier; de Wit, Julien; Queloz, Didier; Triaud, Amaury H. M. J.

2018-01-01

TRAPPIST-1 is an ultracool dwarf star transited by seven Earth-sized planets, for which thorough characterization of atmospheric properties, surface conditions encompassing habitability, and internal compositions is possible with current and next-generation telescopes. Accurate modeling of the star is essential to achieve this goal. We aim to obtain updated stellar parameters for TRAPPIST-1 based on new measurements and evolutionary models, compared to those used in discovery studies. We present a new measurement for the parallax of TRAPPIST-1, 82.4 ± 0.8 mas, based on 188 epochs of observations with the TRAPPIST and Liverpool Telescopes from 2013 to 2016. This revised parallax yields an updated luminosity of {L}* =(5.22+/- 0.19)× {10}-4 {L}ȯ , which is very close to the previous estimate but almost two times more precise. We next present an updated estimate for TRAPPIST-1 stellar mass, based on two approaches: mass from stellar evolution modeling, and empirical mass derived from dynamical masses of equivalently classified ultracool dwarfs in astrometric binaries. We combine them using a Monte-Carlo approach to derive a semi-empirical estimate for the mass of TRAPPIST-1. We also derive estimate for the radius by combining this mass with stellar density inferred from transits, as well as an estimate for the effective temperature from our revised luminosity and radius. Our final results are {M}* =0.089+/- 0.006 {M}ȯ , {R}* =0.121+/- 0.003 {R}ȯ , and {T}{eff} = 2516 ± 41 K. Considering the degree to which the TRAPPIST-1 system will be scrutinized in coming years, these revised and more precise stellar parameters should be considered when assessing the properties of TRAPPIST-1 planets.

Updated neutronics analyses of a water cooled ceramic breeder blanket for the CFETR

NASA Astrophysics Data System (ADS)

Xiaokang, ZHANG; Songlin, LIU; Xia, LI; Qingjun, ZHU; Jia, LI

2017-11-01

The water cooled ceramic breeder (WCCB) blanket employing pressurized water as a coolant is one of the breeding blanket candidates for the China Fusion Engineering Test Reactor (CFETR). Some updating of neutronics analyses was needed, because there were changes in the neutronics performance of the blanket as several significant modifications and improvements have been adopted for the WCCB blanket, including the optimization of radial build-up and customized structure for each blanket module. A 22.5 degree toroidal symmetrical torus sector 3D neutronics model containing the updated design of the WCCB blanket modules was developed for the neutronics analyses. The tritium breeding capability, nuclear heating power, radiation damage, and decay heat were calculated by the MCNP and FISPACT code. The results show that the packing factor and 6Li enrichment of the breeder should both be no less than 0.8 to ensure tritium self-sufficiency. The nuclear heating power of the blanket under 200 MW fusion power reaches 201.23 MW. The displacement per atom per full power year (FPY) of the plasma-facing component and first wall reach 0.90 and 2.60, respectively. The peak H production rate reaches 150.79 appm/FPY and the peak He production reaches 29.09 appm/FPY in blanket module #3. The total decay heat of the blanket modules is 2.64 MW at 1 s after shutdown and the average decay heat density can reach 11.09 kW m-3 at that time. The decay heat density of the blanket modules slowly decreases to lower than 10 W m-3 in more than ten years.

Verification and Updating of the Database of Topographic Objects with Geometric Information About Buildings by Means of Airborne Laser Scanning Data

NASA Astrophysics Data System (ADS)

Mendela-Anzlik, Małgorzata; Borkowski, Andrzej

2017-06-01

Airborne laser scanning data (ALS) are used mainly for creation of precise digital elevation models. However, it appears that the informative potential stored in ALS data can be also used for updating spatial databases, including the Database of Topographic Objects (BDOT10k). Typically, geometric representations of buildings in the BDOT10k are equal to their entities in the Land and Property Register (EGiB). In this study ALS is considered as supporting data source. The thresholding method of original ALS data with the use of the alpha shape algorithm, proposed in this paper, allows for extraction of points that represent horizontal cross section of building walls, leading to creation of vector, geometric models of buildings that can be then used for updating the BDOT10k. This method gives also the possibility of an easy verification of up-to-dateness of both the BDOT10k and the district EGiB databases within geometric information about buildings. For verification of the proposed methodology there have been used the classified ALS data acquired with a density of 4 points/m2. The accuracy assessment of the identified building outlines has been carried out by their comparison to the corresponding EGiB objects. The RMSE values for 78 buildings are from a few to tens of centimeters and the average value is about 0,5 m. At the same time for several objects there have been revealed huge geometric discrepancies. Further analyses have shown that these discrepancies could be resulted from incorrect representations of buildings in the EGiB database.

Evaluation and Validation of Updated MODIS C6 and VIIRS LAI/FPAR

NASA Astrophysics Data System (ADS)

Yan, K.; Park, T.; Chen, C.; Yang, B.; Yan, G.; Knyazikhin, Y.; Myneni, R. B.; CHOI, S.

2015-12-01

Leaf Area Index (LAI) and Fraction of Photosynthetically Active Radiation (0.4-0.7 μm) absorbed by vegetation (FPAR) play a key role in characterizing vegetation canopy functioning and energy absorption capacity. With radiative transfer realization, MODIS onboard NASA EOS Terra and Aqua satellites has provided globally continuous LAI/FPAR since 2000 and continuously updated the products with better quality. And NPP VIIRS shows the measurement capability to extend high-quality LAI/FPAR time series data records as a successor of MODIS. The primary objectives of this study are 1) to evaluate and validate newly updated MODIS Collection 6 (C6) LAI/FPAR product which has finer resolution (500m) and improved biome type input, and 2) to examine and adjust VIIRS LAI/FPAR algorithm for continuity with MODIS'. For MODIS C6 investigation, we basically measure the spatial coverage (i.e., main radiative transfer algorithm execution), continuity and consistency with Collection 5 (C5), and accuracy with field measured LAI/FPAR. And we also validate C6 LAI/FPAR via comparing other possible global LAI/FPAR products (e.g., GLASS and CYCLOPES) and capturing co-varying seasonal signatures with climatic variables (e.g., temperature and precipitation). For VIIRS evaluation and adjustment, we first quantify possible difference between C5 and MODIS heritage based VIIRS LAI/FPAR. Then based on the radiative transfer theory of canopy spectral invariants, we find VIIRS- and biome-specific configurable parameters (single scattering albedo and uncertainty). These two practices for MODIS C6 and VIIRS LAI/FPAR products clearly suggest that (a) MODIS C6 has better coverage and accuracy than C5, (b) C6 shows consistent spatiotemporal pattern with C5, (c) VIIRS has the potential for producing MODIS-like global LAI/FPAR Earth System Data Records.

75 FR 52355 - A Review of Information Published Since 1995 on Coal Mine Dust Exposures and Associated Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-25

... NIOSH-210] A Review of Information Published Since 1995 on Coal Mine Dust Exposures and Associated... Intelligence Bulletin entitled ``A Review of Information Published Since 1995 on Coal Mine Dust Exposures and... document updates and supports the coal mine dust Recommended Exposure Limit (REL) of 1 mg/m\\3\\ that was...

Foreign Language Analysis and Recognition (FLARe) Initial Progress

DTIC Science & Technology

2012-11-29

University Language Modeling ToolKit CoMMA Count Mediated Morphological Analysis CRUD Create, Read , Update & Delete CPAN Comprehensive Perl Archive...DATES COVERED (From - To) 1 October 2010 – 30 September 2012 4. TITLE AND SUBTITLE Foreign Language Analysis and Recognition (FLARe) Initial Progress...AFRL-RH-WP-TR-2012-0165 FOREIGN LANGUAGE ANALYSIS AND RECOGNITION (FLARE) INITIAL PROGRESS Brian M. Ore

75 FR 28057 - Notice of Public Meeting: Resource Advisory Council to the Boise District, Bureau of Land...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-19

... implementation of the Owyhee Public Lands Management Act (OMA) will be provided. Field Office managers will.... DATES: The meeting will be held June 9, 2010 at the Boise District Offices beginning at 9 a.m. and... the Field Office Updates. FOR FURTHER INFORMATION CONTACT: MJ Byrne, Public Affairs Officer and RAC...

DCSS Semi-Annual Tire Conference. CATL Update

DTIC Science & Technology

2009-03-25

1 a/s, AP, PS X1.3.41 ACTS-CATL-T1-1/98-053 Durango All Terrain...1 a/s, A/t, AP, PS X1.3.109 ACTS-CATL-T1-1/98-053 Durango Radial XTR 1...a/s, a/t, AP, PS X1.3.110 ACTS-CATL-T1-1/98-053 Durango M/T 1 a/t

Functional Characterization of a Novel Pro-Apoptotic Transcription Regulatory Protein in Ovarian Cancer

DTIC Science & Technology

2006-12-01

increasing age ( Waki et al., 2003; Hatakeyama et al., 2004). We did not see a strong correlation to increasing age as a factor in biallelic methylation...Strathdee G and Brown R. (2004). Drug Resist. Update, 7, 267–278. Waki T, Tamura G, Sato M and Motoyama T. (2003). Oncogene, 22, 4128–4133. Williams JW, Hawes

Working Memory and Mental Arithmetic: A Case for Dual Central Executive Resources

ERIC Educational Resources Information Center

Ketelsen, Kirk; Welsh, Marilyn

2010-01-01

The current study was designed to examine the possible existence of two limited-capacity pools of central executive resources: one each for verbal and visuospatial processing. Ninety-one college students (M age = 19.0, SD = 2.2) were administered a verbal working memory task that involved updating numbers in 2-, 3-, and 4-load conditions. The task…

East Texas, 2012—Forest Inventory and Analysis Factsheet

Treesearch

Thomas J. Brandeis; Jason A. Cooper; James W. Bentley

2014-01-01

This science update summarizes the findings of the statewide annual inventory of the forest resource attributes in Texas conducted by the Southern Forest Inventory and Analysis (FIA) Program in cooperation with the Texas A&M Forest Service. The 254 counties of Texas are consolidated into seven FIA survey units—southeast (unit 1), northeast (unit 2), north central (...

77 FR 56563 - Snapper-Grouper Fishery of the South Atlantic; Reopening of the 2012 Commercial Sector for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-13

... exclusive economic zone (EEZ). NMFS previously determined the commercial ACL for yellowtail snapper would be... Atlantic EEZ at 12:01 a.m. on September 11, 2012. Updated landings estimates indicate the ACL will not be..., September 11, 2012, through December 31, 2012, the end of the fishing season, unless the ACL is reached...

78 FR 64888 - Coastal Migratory Pelagic Resources of the Gulf of Mexico and South Atlantic; Reopening of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-30

... the commercial annual catch limit (ACL) (equal to the commercial quota) for king mackerel in the...:01 a.m., local time, on July 1, 2014. However, updated landings estimates indicate the commercial ACL...-Stevens Act) by regulations at 50 CFR part 622. NMFS projected that the commercial annual catch limit (ACL...

New Technology Tools: Using Social Media for Alcohol, Drug Abuse, and Violence Prevention. Prevention Update

ERIC Educational Resources Information Center

Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2011

2011-01-01

When it comes to using social media technology for alcohol, drug abuse, and violence prevention, Thomas Workman, at Baylor College of Medicine's John M. Eisenberg Center for Clinical Decisions and Communications Science, points out that social media is interactive. This means that a person is entering a conversation rather than a declaration, and…

Completion of the 2011 National Land Cover Database for the Conterminous United States – Representing a Decade of Land Cover Change Information

EPA Science Inventory

The National Land Cover Database (NLCD) provides nationwide data on land cover and land cover change at the native 30-m spatial resolution of the Landsat Thematic Mapper (TM). The database is designed to provide five-year cyclical updating of United States land cover and associat...

An update of the Near-Earth Asteroid Tracking/Maui Space Surveillance System (NEAT/MSSS) collaboration

NASA Technical Reports Server (NTRS)

Bambery, R. J.; Helin, E. F.; Pravdo, S. H.; Lawrence, K. J.; Hicks, M. D.

2002-01-01

Jet Propulsion Laboratory's (JPL) Near-Earth Asteroid Tracking (NEAT) program has two simultaneously-operating, autonomous search systems on two geographically-separated 1.2-m telescopes; one at the Maui Space Surveillance System (NEAT/MSSS) and the other on the Palomar Observatory's Oschin telescope (NEAT/Palomar). This paper will focus exclusively on the NEAT/MSSS system.

CCD Parallaxes for 309 Late-type Dwarfs and Subdwarfs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dahn, Conard C.; Harris, Hugh C.; Subasavage, John P.

2017-10-01

New, updated, and/or revised CCD parallaxes determined with the Strand Astrometric Reflector at the Naval Observatory Flagstaff Station are presented. Included are results for 309 late-type dwarf and subdwarf stars observed over the 30+ years that the program operated. For 124 of the stars, parallax determinations from other investigators have already appeared in the literature and we compare the different results. Also included here are new or updated VI photometry on the Johnson–Kron-Cousins system for all but a few of the faintest targets. Together with 2MASS JHK{sub s} near-infrared photometry, a sample of absolute magnitude versus color and color versusmore » color diagrams are constructed. Because large proper motion was a prime criterion for targeting the stars, the majority turn out to be either M-type subdwarfs or late M-type dwarfs. The sample also includes 50 dwarf or subdwarf L-type stars, and four T dwarfs. Possible halo subdwarfs are identified in the sample based on tangential velocity, subluminosity, and spectral type. Residuals from the solutions for parallax and proper motion for several stars show evidence of astrometric perturbations.« less

Updating the distribution and habitat pattern of Maurolicus stehmanni (Sternoptychidae, Stomiformes) in the Southwest Atlantic Ocean

NASA Astrophysics Data System (ADS)

Belleggia, Mauro; Villanueva-Gomila, Gabriela Lujan; Buratti, Claudio; Colombo, Gustavo Alvarez; Figueroa, Daniel Enrique; Venerus, Leonardo Ariel

2018-06-01

We updated the distribution and habitat patterns of Maurolicus stehmanni in the Southwest Atlantic Ocean by compiling data obtained from research surveys conducted on the Argentinean continental shelf, as well as from opportunistic records. This paper confirms the presence of M. stehmanni in the Argentinean continental shelf, extending its southernmost distributional limit by ca. 1000 km (from 43.0°S to 52.2°S). Adult specimens of M. stehmanni were collected in various locations from 2004 to 2016. Eggs and larvae of Maurolicus spp. were caught during ichthyoplankton tows carried out from 2003 to 2013. The present paper furthermore extends the habitat type in which this species was recorded: specimens were found in the inner continental shelf (between 46.2°S and 52.2°S) instead of the shelf break and continental slope. Two specimens were found lying dead upon the beach of Puerto Madryn, Nuevo Gulf (42.8°S). The presence of eggs and larvae in coastal embayments (San Matías and San José gulfs), in concomitant occurrence with adults, may suggest the establishment of this species in the region.

Fixed interval smoothing with discrete measurements.

NASA Technical Reports Server (NTRS)

Bierman, G. J.

1972-01-01

Smoothing equations for a linear continuous dynamic system with linear discrete measurements, derived from the discrete results of Rauch, Tung, and Striebel (1965), (R-T-S), are used to extend, through recursive updating, the previously published results of Bryson and Frazier (1963), (B-F), and yield a modified Bryson and Frazier, (M-B-F), algorithm. A comparison of the (M-B-F) and (R-T-S) algorithms leads to the conclusion that the former is to be preferred because it entails less computation, less storage, and less instability. It is felt that the presented (M-B-F) smoothing algorithm is a practical mechanization and should be of value in smoothing discretely observed dynamic linear systems.

PIP-II Injector Test Warm Front End: Commissioning Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prost, Lionel R.; et al.

The Warm Front End (WFE) of the Proton Improvement Plan II Injector Test [1] at Fermilab has been constructed to its full length. It includes a 15-mA DC, 30-keV H- ion source, a 2 m-long Low Energy Beam Transport (LEBT) with a switching dipole magnet, a 2.1 MeV CW RFQ, followed by a Medium Energy Beam Transport (MEBT) with various diagnostics and a dump. This report presents the commissioning status, focusing on beam measurements in the MEBT. In particular, a beam with the parameters required for injection into the Booster (5 mA, 0.55 ms macro-pulse at 20 Hz) was transportedmore » through the WFE.« less

Guideline on terminology and definitions of updating clinical guidelines: The Updating Glossary.

PubMed

Martínez García, Laura; Pardo-Hernández, Hector; Sanabria, Andrea Juliana; Alonso-Coello, Pablo; Penman, Katrina; McFarlane, Emma

2018-03-01

The Guidelines International Network (G-I-N) Updating Guidelines Working Group launched an initiative to develop a glossary (the Updating Glossary) with domains, terms, definitions, and synonyms related to updating of clinical guidelines (CGs). The steering committee developed an initial list of domains, terms, definitions, and synonyms through brainstorming and discussion. The panel members participated in three rounds of feedback to discuss, refine, and clarify the proposed terms, definitions, and synonyms. Finally, the panel members were surveyed to assess their level of agreement regarding the glossary. Eighteen terms were identified and defined: (1) continuous updating, (2) decision to update, (3) fixed updating, (4) full updating, (5) impact of the new evidence, (6) partial updating, (7) prioritization process, (8) reporting process, (9) signal for an update, (10) surveillance process, (11) time of validity, (12) timeframe, (13) tools and resources, (14) up to date, (15) update cycle, (16) update unit, (17) updated version, and (18) updating strategy. Consensus was reached for all terms, definitions, and synonyms (median agreement scores ≥ 6); except for one term. The G-I-N Updating Guidelines Working Group assembled the Updating Glossary to facilitate and improve the knowledge exchange among CGs developers, researchers, and users. Copyright © 2017 Elsevier Inc. All rights reserved.

Update on radionuclide imaging in hepatobiliary disease. [/sup 99m/Tc-labelled acetanilide iminodracetic acid analogues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenthall, L.

1981-05-01

The recent introduction of technetium Tc 99m-labeled acetanilide iminodiacetic acid (/sup 99m/Tc-IDA) analogues has facilitated the clincal study of the bile flow pathways. A variety of /sup 99m/Tc-IDA derivaties are under investigation. Basically all are metabolized by the hepatocyte and immediately thereafter excreted unconjugated into the biliary tract. Of the various derivatives tested, e.g., dimethyl (lidofenin), diethyl, paraisopropyl (iprofenin), parabutyl (butilfenin), and diisopropyl (disofenin), the last named is the best universal agent at this time. By serial liver imaging the patency of the cystic duct and the integrity of altered cholangiointestinal anatomy can be assessed, leakage of bile and gastricmore » reflux can be disclosed, and medical and surgical jaundice can be distinguished.« less

Working Memory Updating Latency Reflects the Cost of Switching between Maintenance and Updating Modes of Operation

ERIC Educational Resources Information Center

Kessler, Yoav; Oberauer, Klaus

2014-01-01

Updating and maintenance of information are 2 conflicting demands on working memory (WM). We examined the time required to update WM (updating latency) as a function of the sequence of updated and not-updated items within a list. Participants held a list of items in WM and updated a variable subset of them in each trial. Four experiments that vary…

The Modeling and Simulation Catalog for Discovery, Knowledge and Reuse

NASA Technical Reports Server (NTRS)

Stone, George F. III; Greenberg, Brandi; Daehler-Wilking, Richard; Hunt, Steven

2011-01-01

The DoD M&S Steering Committee has noted that the current DoD and Service's modeling and simulation resource repository (MSRR) services are not up-to-date limiting their value to the using communities. However, M&S leaders and managers also determined that the Department needs a functional M&S registry card catalog to facilitate M&S tool and data visibility to support M&S activities across the DoD. The M&S Catalog will discover and access M&S metadata maintained at nodes distributed across DoD networks in a centrally managed, decentralized process that employs metadata collection and management. The intent is to link information stores, precluding redundant location updating. The M&S Catalog uses a standard metadata schemas based on the DoD's Net-Centric Data Strategy Community of Interest metadata specification. The Air Force, Navy and OSD (CAPE) have provided initial information to participating DoD nodes, but plans on the horizon are being made to bring in hundreds of source providers.

Long-term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: final update of the pivotal ERIVANCE BCC study.

PubMed

Sekulic, Aleksandar; Migden, Michael R; Basset-Seguin, Nicole; Garbe, Claus; Gesierich, Anja; Lao, Christopher D; Miller, Chris; Mortier, Laurent; Murrell, Dedee F; Hamid, Omid; Quevedo, Jorge F; Hou, Jeannie; McKenna, Edward; Dimier, Natalie; Williams, Sarah; Schadendorf, Dirk; Hauschild, Axel

2017-05-16

In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration-approved Hedgehog pathway inhibitor, showed objective response rates (ORRs) by independent review facility (IRF) of 30% and 43% in metastatic basal cell carcinoma (mBCC) and locally advanced BCC (laBCC), respectively. ORRs by investigator review were 45% (mBCC) and 60% (laBCC). Herein, we present long-term safety and final investigator-assessed efficacy results in patients with mBCC or laBCC. One hundred four patients with measurable advanced BCC received oral vismodegib 150 mg once daily until disease progression or intolerable toxicity. The primary end point was IRF-assessed ORR. Secondary end points included ORR, duration of response (DOR), progression-free survival, overall survival (OS), and safety. At data cutoff (39 months after completion of accrual), 8 patients were receiving the study drug (69 patients in survival follow-up). Investigator-assessed ORR was 48.5% in the mBCC group (all partial responses) and 60.3% in the laBCC group (20 patients had complete response and 18 patients had partial response). ORRs were comparable across patient subgroups, including aggressive histologic subtypes (eg, infiltrative BCC). Median DOR was 14.8 months (mBCC) and 26.2 months (laBCC). Median OS was 33.4 months in the mBCC cohort and not estimable in the laBCC cohort. Adverse events remained consistent with clinical experience. Thirty-three deaths (31.7%) were reported; none were related to vismodegib. This long-term update of the ERIVANCE BCC trial demonstrated durability of response, efficacy across patient subgroups, and manageable long-term safety of vismodegib in patients with advanced BCC. This study was registered prospectively with Clinicaltrials.gov , number NCT00833417 on January 30, 2009.

Efficient Synthesis of Network Updates

DTIC Science & Technology

2015-06-17

model include switches S i , links L j , and a single controller element C, and a network N is a tuple containing these. Each switch S i is encoded as a...and the ports they should be forwarded to respec- tively. Each link L j is represented by a record consisting of two locations loc and loc0 and a list...the union of multisets m1 and m2. We write [x] for a singleton list, and l1@l2 for concatenation of l1 and l2. Each transition N o ! N 0 is anno - tated

Larva and pupa of Megatoma (s. str.) undata (Linnaeus, 1758) with remarks on biology and economic importance (Coleoptera, Dermestidae)

PubMed Central

Kadej, Marcin

2017-01-01

Abstract An updated description of the final larval instar and pupa of Megatoma (s. str.) undata (Linnaeus, 1758) (Coleoptera: Dermestidae) is presented. Several morphological characteristics of M. undata larvae are documented and discussed: antenna, epipharynx, mandibula, maxilla, ligula with labial palpi, hastisetae, terga, and condition of the antecostal suture. The paper is fully illustrated and includes some important additions to extend notes on this species available in the references. Summarised data about biology, economic importance, and distribution of M. undata are also provided. PMID:29134022

New results from RENO & prospects with RENO-50

NASA Astrophysics Data System (ADS)

Joo, K. K.

2017-09-01

This paper briefly describes recent progress of RENO and next generation future prospect of the reactor neutrino oscillation experiment, RENO-50. Recently the RENO experiment has updated its latest value on sin22θ 13 and provided new results on 5 MeV excess, Δm2 ee, θ 13 with n-H analysis, absolute antineutrino flux measurement, and sterile neutrino search. It gives rich programs of neutrino properties, detector development, nuclear monitoring and application. Using reactor neutrinos, the future RENO-50 experiment will search for more precise measurement of θ 12, Δm 2 12 and mass hierarchy.

Development of a Low-Cost Method for Whole-Spacecraft Isolation of Small Satellites

DTIC Science & Technology

2017-01-10

c*m1* omega (i)^ 3 *j + c*m2* omega (i)^ 3 *j); % Sff(i)=(1+( omega (i)/w2/Q)^2)/((1-( omega (i)/w2)^2)^2+( omega (i)/... w2/Q)^2)*ABC_MPE_full(i)*abs(H2(i))^2...Paperwork Reduction Project (0704-0188) Washington DC 20503. 1. AGENCY USE ONLY (Leave Blank) 2. REPORT DATE December 2015 3 . REPORT TYPE AND DATES COVERED... 3 Incorporating Isolators on NPSCuL 41 3.1 Design Updates to NPSCuL . . . . . . . . . . . . . . . . . . . . 41 3.2 Test Set-Up and Configurations

Data update in a land information network

NASA Astrophysics Data System (ADS)

Mullin, Robin C.

1988-01-01

The on-going update of data exchanged in a land information network is examined. In the past, major developments have been undertaken to enable the exchange of data between land information systems. A model of a land information network and the data update process have been developed. Based on these, a functional description of the database and software to perform data updating is presented. A prototype of the data update process was implemented using the ARC/INFO geographic information system. This was used to test four approaches to data updating, i.e., bulk, block, incremental, and alert updates. A bulk update is performed by replacing a complete file with an updated file. A block update requires that the data set be partitioned into blocks. When an update occurs, only the blocks which are affected need to be transferred. An incremental update approach records each feature which is added or deleted and transmits only the features needed to update the copy of the file. An alert is a marker indicating that an update has occurred. It can be placed in a file to warn a user that if he is active in an area containing markers, updated data is available. The four approaches have been tested using a cadastral data set.

NEPSY-II Review: Korkman, M., Kirk, U., & Kemp, S. (2007). "NEPSY--Second Edition" (NEPSY-II). San Antonio, TX: Harcourt Assessment

ERIC Educational Resources Information Center

Davis, John L.; Matthews, Robb N.

2010-01-01

This article presents a review of the "NEPSY-Second Edition" (NEPSY-II), an updated and modified version of the NEPSY (Korkman, Kirk, & Kemp, 1998). The NEPSY-II is an individually administered compendium of tests designed to assess neuropsychological development in children ranging from 3 to 16.11 years old. The authors of the…

Determinants of Success for Online Communities: An Analysis of Three Communities in Terms of Members' Perceived Professional Development

ERIC Educational Resources Information Center

Hew, Khe Foon

2009-01-01

Recent empirical evidence suggests that the updated DeLone and McLean's information systems (D&M IS) model can identify the determinants of success of online communities in terms of member loyalty (Lin and Lee 2006). This study is similarly concerned with the challenge of identifying the determinants of success of online communities, but it…

Sexual Orientation and U.S. Military Personnel Policy: An Update of RAND’s 1993 Study

DTIC Science & Technology

2010-01-01

Klepinger, “The Sexual Behavior of Men in the United States,” Family Planning Perspectives, Vol. 25, No. 2, 1993, pp. 52–60. Black, D., Gary Gates, Seth ...Kestnbaum, “Professional Closure in the Military Labor Market: A Critique of Pure Cohesion,” in D. M. Snider and G. L. Watkins , eds., The Future of

Optimal uneven-aged stocking guides: an application to spruce-fir stands in New England

Treesearch

Jeffrey H. Gove; Mark J. Ducey

2014-01-01

Management guides for uneven-aged forest stands periodically need to be revisited and updated based on new information and methods. The current silvicultural guide for uneven-aged spruce-fir management in Maine and the northeast (Frank, R.M. and Bjorkbom, J.C. 1973 A silvicultural guide for spruce-fir in the northeast. General Technical Report NE-6, Forest Service. U.S...

NIH–Lacks Family Partnership Gives Henrietta Lacks’ Descendants a Seat at the Table | Poster

Cancer.gov

The NIH Bethesda campus recently welcomed several special guests for a presentation titled Given a Voice: Update on the NIH–Lacks Family Partnership. Henrietta Lacks’ grandchildren Jeri Lacks-Whye (who is also the Lacks family spokesperson) and David Lacks, Jr. came to speak with NIH Director Francis S. Collins, Ph.D., M.D. about the importance of protecting patients and their

75 FR 73014 - Notice of Public Meeting: Updating the Flight Instructor Renewal Process To Enhance Safety of Flight

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

... capacity, we may request that those who are planning on sending more than a single representative reduce... accommodate all persons wishing to attend. The FAA asks that participants sign in at 9 a.m. on each day of the... information gathering meeting. DATES: The public meetings will be held on the following dates. December 6...

A Search for Astrometric Companions to Stars in the Southern Hemisphere

DTIC Science & Technology

2009-05-05

18 52 00.17 −60 46 11.3 M3.5 V 13.4 … 6, 8 a 2MASS coordinates (Skrutskie et al. 2006) were updated with Begam et al. (2009, in preparation) relative...behalf of the Particle Physics and Astronomy Re- search Council (PPARC). This research made use of data products from 2MASS , which is a joint project

Principled Design of an Augmented Reality Trainer for Medics

DTIC Science & Technology

2018-04-13

retake test is scheduled. In addition, extensive simulation capstone scenarios are run with a full body manikin that includes airway management...platform so they could run with high quality graphical resolution. We updated the underlying data models to reflect the training scenario parameters...Sedeh, P., Schumann, M., & Groeben, H. (2009). Laryngoscopy via Macintosh blade versus GlideScope: Success rate and time for endotracheal intubation

Electronic Warfare and Radar Systems Engineering Handbook

DTIC Science & Technology

2012-06-01

Airframe Missile, or Reliability, Availability, and Maintainability R&M Reliability and Maintainability RAT Ram Air Turbine RBOC Rapid Blooming...the Doppler shifted return (see Figure 10). Reflections off rotating jet engine compressor blades, aircraft propellers, ram air turbine (RAT...predict aircraft ground speed and direction of motion. Wind influences are taken into account, such that the radar can also be used to update the aircraft

Cost Analysis Sources and Documents Data Base Reference Manual (Update)

DTIC Science & Technology

1989-06-01

M: Refcrence Manual PRICE H: Training Course Workbook 11. Use in Cost Analysis. Important source of cost estimates for electronic and mechanical...Nature of Data. Contains many microeconomic time series by month or quarter. 5. Level of Detail. Very detailed. 6. Normalization Processes Required...Reference Manual. Moorestown, N.J,: GE Corporation, September 1986. 64. PRICE Training Course Workbook . Moorestown, N.J.: GE Corporation, February 1986

Rochester Connectionist Papers. 1979-1985

DTIC Science & Technology

1985-12-01

updated and improved version of the thesis account of recent neurolinguistic data. Fanty, M., "Context-free parsing in connectionist networks." TR 174...April 1982. Our first large program in the connectionist paradigm. It simulates a multi- layer network for recognizing line drawings of Origami figures...The program successfully deals with noise and simple occlusion and the thesis incorporates many key ideas on designing and running large models. Small

Evolution of Languages for Specific Purposes Programs in the United States: 1990-2011

ERIC Educational Resources Information Center

Long, Mary K.; Uscinski, Izabela

2012-01-01

This article reports the results of a national survey of LSP offerings in U.S. higher education conducted during 2011. The survey updates one carried out by Christine Uber-Grosse and Geoffrey M. Voght in 1990. The data provide: (a) a profile of institutions that offer LSP; (b) an overview of the number, type, level, and enrollment in LSP courses;…

Using Optical Interferometry for GEO Satellites Imaging: An Update

DTIC Science & Technology

2016-05-27

of a geostationary satellite using the Navy Precision Optical Inter- ferometer (NPOI) during the glint season of March 2015. We succeeded in detecting...night. These baseline lengths correspond to a resolution of ∼4 m at geostationary altitude. This is the first multiple-baseline interferometric...detection of a satellite. Keywords: geostationary satellites, optical interferometry, imaging, telescope arrays 1. INTRODUCTION Developing the ability to

DNA Vaccination Against Metastatic Breast Cancer

DTIC Science & Technology

2002-07-01

Although DNA vaccines have shown effectiveness in clinical trials , it is essential to demonstrate pre- clinical effectiveness for anti-tumor DNA vaccines...been shown to induce strong anti-tumor immunity in mice (3). Although gene vaccines have shown effectiveness in clinical trials for infectious...stronger justification for a clinical trial . REFERENCES: 1. Fornier, M., P. Munster, and A. D. Seidman. 1999. Update on the management of advanced breast

Airborne Network Optimization with Dynamic Network Update

DTIC Science & Technology

2015-03-26

Faculty Department of Electrical and Computer Engineering Graduate School of Engineering and Management Air Force Institute of Technology Air University...Member Dr. Barry E. Mullins Member AFIT-ENG-MS-15-M-030 Abstract Modern networks employ congestion and routing management algorithms that can perform...airborne networks. Intelligent agents can make use of Kalman filter predictions to make informed decisions to manage communication in airborne networks. The

Updating of Safety Criteria for Basic Diagnostic Indicators of Dam at the Sayano-Shushenskaya HPP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gordon, L. A.; Skvortsova, A. E.

2013-09-15

Values of diagnostic indicators [K]-limitations placed on radial displacements and turn angles of horizontal sections of the dam - which are permitted for each upper-pool level within the range from 520 to 539 m are determined and proposed for inclusion in the Declaration of Safety. Empirical relationships used to develop safety criteria K1 and K2 are modified.

Mini-dome Fresnel lens photovoltaic concentrator development

NASA Technical Reports Server (NTRS)

Oneill, Mark J.; Piszczor, Michael F., Jr.

1991-01-01

Since 1986 work on a new high-performance, light-weight space photovoltaic concentration array has been conducted. An update on the mini-dome lens concentrator array development program is provided. Recent prototype cell and lens test results indicate that near-term array performance goals of 300 w/sq m and 100 w/kg are feasible, and that a longer-term goal of 200 w/kg is reasonable.

Numerical modeling of flow and transport in the far-field of a generic nuclear waste repository in fractured crystalline rock using updated fracture continuum model

NASA Astrophysics Data System (ADS)

Hadgu, T.; Kalinina, E.; Klise, K. A.; Wang, Y.

2016-12-01

Disposal of high-level radioactive waste in a deep geological repository in crystalline host rock is one of the potential options for long term isolation. Characterization of the natural barrier system is an important component of the disposal option. In this study we present numerical modeling of flow and transport in fractured crystalline rock using an updated fracture continuum model (FCM). The FCM is a stochastic method that maps the permeability of discrete fractures onto a regular grid. The original method by McKenna and Reeves (2005) has been updated to provide capabilities that enhance representation of fractured rock. As reported in Hadgu et al. (2015) the method was first modified to include fully three-dimensional representations of anisotropic permeability, multiple independent fracture sets, and arbitrary fracture dips and orientations, and spatial correlation. More recently the FCM has been extended to include three different methods. (1) The Sequential Gaussian Simulation (SGSIM) method uses spatial correlation to generate fractures and define their properties for FCM (2) The ELLIPSIM method randomly generates a specified number of ellipses with properties defined by probability distributions. Each ellipse represents a single fracture. (3) Direct conversion of discrete fracture network (DFN) output. Test simulations were conducted to simulate flow and transport using ELLIPSIM and direct conversion of DFN methods. The simulations used a 1 km x 1km x 1km model domain and a structured with grid block of size of 10 m x 10m x 10m, resulting in a total of 106 grid blocks. Distributions of fracture parameters were used to generate a selected number of realizations. For each realization, the different methods were applied to generate representative permeability fields. The PFLOTRAN (Hammond et al., 2014) code was used to simulate flow and transport in the domain. Simulation results and analysis are presented. The results indicate that the FCM approach is a viable method to model fractured crystalline rocks. The FCM is a computationally efficient way to generate realistic representation of complex fracture systems. This approach is of interest for nuclear waste disposal models applied over large domains. SAND2016-7509 A

Updates to a 13C metabolic flux analysis model for evaluating energy metabolism in cultured cerebellar granule neurons from neonatal rats.

PubMed

Jekabsons, Mika B; Gebril, Hoda M; Wang, Yan-Hong; Avula, Bharathi; Khan, Ikhlas A

2017-10-01

A hexose phosphate recycling model previously developed to infer fluxes through the major glucose consuming pathways in cultured cerebellar granule neurons (CGNs) from neonatal rats metabolizing [1,2- 13 C 2 ]glucose was revised by considering reverse flux through the non-oxidative pentose phosphate pathway (PPP) and symmetrical succinate oxidation within the tricarboxylic acid (TCA) cycle. The model adjusts three flux ratios to effect 13 C distribution in the hexose, pentose, and triose phosphate pools, and in TCA cycle malate to minimize the error between predicted and measured 13 C labeling in exported lactate (i.e., unlabeled, single-, double-, and triple-labeled; M, M1, M2, and M3, respectively). Inclusion of reverse non-oxidative PPP flux substantially increased the number of calculations but ultimately had relatively minor effects on the labeling of glycolytic metabolites. From the error-minimized solution in which the predicted M-M3 lactate differed by 0.49% from that measured by liquid chromatography-triple quadrupole mass spectrometry, the neurons exhibited negligible forward non-oxidative PPP flux. Thus, no glucose was used by the pentose cycle despite explicit consideration of hexose phosphate recycling. Mitochondria consumed only 16% of glucose while 45% was exported as lactate by aerobic glycolysis. The remaining 39% of glucose was shunted to pentose phosphates presumably for de novo nucleotide synthesis, but the proportion metabolized through the oxidative PPP vs. the reverse non-oxidative PPP could not be determined. The lactate exported as M1 (2.5%) and M3 (1.2%) was attributed to malic enzyme, which was responsible for 7.8% of pyruvate production (vs. 92.2% by glycolysis). The updated model is more broadly applicable to different cell types by considering bi-directional flux through the non-oxidative PPP. Its application to cultured neurons utilizing glucose as the sole exogenous substrate has demonstrated substantial oxygen-independent glucose utilization by aerobic glycolysis as well as the oxidative PPP and/or reverse non-oxidative PPP, but negligible glucose consumption by the pentose cycle. Copyright © 2017 Elsevier Ltd. All rights reserved.

Methane emissions from tundra environments in the Yukon-Kuskokwin Delta, Alaska

NASA Technical Reports Server (NTRS)

Bartlett, Karen B.; Crill, Patrick M.; Sass, Ronald L.; Harriss, Robert C.; Dise, Nancy B.

1992-01-01

This paper reports CH4 flux to the atmosphere from a variety of tundra environments near Bethel, Alaska during the summer months of 1988. Emissions from wet meadow tundra averaged 144 +/- 31 mg/sq m/d and ranged from 15.6 to 426 mg/sq m/d varying with soil moisture and temperature. Flux from the drier upland tundra was about two orders of magnitude lower and averaged 2.3 +/- 1.1 mg/sq m/d. Tundra lakes emit CH4 from the open water surface as well as from fringing aquatic vegetation; the presence of vegetation significantly enhanced flux over open water rates. Calculated diffusive fluxes from open water varied with lake size, the large lakes emitting 3.8 mg/sq m/d and small lakes emitting an average of 77 mg/sq m/d. An updated estimate of global emissions from tundra indicates an annual fluxes of approximately 11 +/- 3 Tg CH4.

Exploration of the West Florida Shelf Blue Holes Investigation of Physical and Biological Characteristics and Archaeological Implications of Unique Karst Features

NASA Astrophysics Data System (ADS)

Culter, J. K.

2006-12-01

The west Florida continental shelf is nearly as large as peninsular Florida and embraces a vast mosaic of marine habitats. The dominant shelf habitats have been described and studied to some degree. However, the offshore submerged sinkhole and spring features (blue holes) have not been scientifically described or studied, with the exception of one site called the Mudhole, a saltwater spring off Ft. Myers Beach. These features are relatively small habitats by standards of aerial coverage, but are probably more common than previously thought. These habitats are very unique shelf features, a reef in reverse, representing island habitats on the Florida shelf. This study was initiated in summer 2005 to describe the biota associated with the offshore blue hole features of this region and search for new sites. Eleven sites off the west central Florida coast have been verified and data has been collected at eight locations, all greater than 30 miles offshore. Most blue holes exhibit similar structural features, which divide the biota into zones. Pelagic species, such as amberjack, occupy the water column above the holes and reef species populate the rim. All of the sites investigated harbor one or more goliath grouper (Epinephelus itajara) and most of the features have resident nurse sharks (Ginglymostoma cirratum). Pelagic sharks periodically visit the sites and sea turtles are frequently observed at or near the holes. Whale sharks (Rhincodon typus) also seem to have an affinity for these features. The reef fauna that occupy the rim rapidly decline in abundance and diversity deeper into the holes with the deepest fauna being calcareous tube dwelling polychaetes that grow down to the edges of the hydrogen sulfide layer. There is pronounced temperature stratification within all holes. All of the sites investigated to date are relatively deep, by standards of recreational scuba diving, and divers utilized open circuit trimix to conduct the investigations. The key components of the documentation of the features included; vertical video transects, still photography, collections of biota, placement of recording thermographs and conductivity meters, collection of bottom sediment and rocks. During the course of the investigation a previously unknown cave feature over 45 meters in height and 76 meters in bottom diameter was discovered and dubbed Megadome. The cave is connected to the Gulf by a circular shaft approximately 0.75 meters in diameter and 11 meters in length. Instrumentation placed at Megadome revealed lunar tidal period water exchange, possible freshwater outflow and water movement in response to hurricanes. The upper portion of the cave contains a fouling community of sponges worms, tunicates and other organisms. A sink hole off the mouth of Tampa Bay was shown to contain a saltwater spring, venting at 72 m (235 fsw). Research is continuing. This research has been supported by a grant from NOAA, Ocean Exploration Program and Mote Marine Laboratory.

Individual differences in executive processing predict susceptibility to interference in verbal working memory.

PubMed

Hedden, Trey; Yoon, Carolyn

2006-09-01

Recent theories have suggested that resistance to interference is a unifying principle of executive function and that individual differences in interference may be explained by executive function (M. J. Kane & R. W. Engle, 2002). Measures of executive function, memory, and perceptual speed were obtained from 121 older adults (ages 63-82). We used structural equation modeling to investigate the relationships of these constructs with interference in a working memory task. Executive function was best described as two related subcomponent processes: shifting and updating goal-relevant representations and inhibition of proactive interference. These subcomponents were distinct from verbal and visual memory and speed. Individual differences in interference susceptibility and recollection were best predicted by shifting and updating and by resistance to proactive interference, and variability in familiarity was predicted by resistance to proactive interference and speed. ((c) 2006 APA, all rights reserved).

Update Direct-Strike Lightning Environment for Stockpile-to-Target Sequence (Second Revision)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uman, Martin A.; Rakov, V. A.; Elisme, J. O.

2010-10-05

The University of Florida has surveyed all relevant publications reporting lightning characteristics and presents here an up-to-date version of the direct-strike lightning environment specifications for nuclear weapons published in 1989 by R. J. Fisher and M. A. Uman. Further, we present functional expressions for current vs. time, current derivative vs. time, second current derivative vs. time, charge transfer vs. time, and action integral (specific energy) vs. time for positive and negative first return strokes, for negative subsequent return strokes, and for positive and negative continuing currents; and we give sets of constants for these functional expressions so that the resultantmore » waveforms exhibit approximately the median and extreme lightning parameters presented in the updated direct strike environment. Fourier transforms of the return stroke current waveforms are presented. The results of our literature survey are included in three Appendices entitled Return Stroke Current, Continuing Current, and Positive Lightning.« less

Progress on development of an airborne two-micron IPDA lidar for water vapor and carbon dioxide column measurements

NASA Astrophysics Data System (ADS)

Singh, Upendra N.; Petros, Mulugeta; Refaat, Tamer F.; Yu, Jirong; Antill, Charles W.; Taylor, Bryant D.; Bowen, Stephen C.; Welters, Angela M.; Remus, Ruben G.; Wong, Teh-Hwa; Reithmaier, Karl; Lee, Jane; Ismail, Syed

2017-09-01

An airborne 2-μm triple-pulse integrated path differential absorption (IPDA) lidar is currently under development at NASA Langley Research Center (LaRC). This lidar targets both atmospheric carbon dioxide (CO2) and water vapor (H2O) column measurements, simultaneously. Advancements in the development of this IPDA lidar are presented in this paper. Updates on advanced two-micron triple-pulse high-energy laser transmitter will be given including packaging and lidar integration status. In addition, receiver development updates will also be presented. This includes a state-of-the-art detection system integrated at NASA Goddard Space Flight Center. This detection system is based on a newly developed HgCdTe (MCT) electron-initiated avalanche photodiode (e-APD) array. Future plan for IPDA lidar system for ground integration, testing and flight validation will be discussed.

Scientific goals of Nano-JASMINE

NASA Astrophysics Data System (ADS)

Yamada, Yoshiyuki; Fujita, Sho; Gouda, Naoteru; Kobayashi, Yukiyasu; Hara, Takuji; Nishi, Ryoichi; Yoshioka, Satoshi; Hozumi, Shunsuke

2013-02-01

Nano-JASMINE is an ultrasmall Japanese satellite (with a weight of 35 kg), designed to carry out an astrometric mission. The target accuracy is 3 milliarcseconds (mas) for stars brighter than magnitude 7.5 at zw-band wavelengths of 0.6-1.0 μm. The observational strategy is the same as that of Gaia and Hipparcos. The time span of 20 years since the Hipparcos mission will enable us to update the proper motion data obtained at that time. With the help of these updated measurements, we expect that some stars will be resolved into multiple stars. In addition, taking advantage of the small primary mirror (with a diameter of 5 cm), we can measure bright stars which cannot be observed with Gaia because of saturation limits. The core data reduction for the Nano-JASMINE mission will use Gaia's Astrometric Global Iterative Solution (agis). A collaboration between the Gaia agis and Nano-JASMINE teams was initiated in 2007.

Hadron spectrum of quenched QCD on a 32{sup 3} {times} 64 lattice

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Seyong; Sinclair, D.K.

1992-10-01

Preliminary results from a hadron spectrum calculation of quenched Quantumchromodynamics on a 32{sup 3} {times} 64 lattice at {beta} = 6.5 are reported. The hadron spectrum calculation is done with staggered quarks of masses, m{sub q}a = 0.001, 0.005 and 0.0025. We use two different sources in order to be able to extract the {Delta} mass in addition to the usual local light hadron masses. The numerical simulation is executed on the Intel Touchstone Delta computer. The peak speed of the Delta for a 16 {times} 32 mesh configuration is 41 Gflops for 32 bit precision. The sustained speed formore » our updating code is 9.5 Gflops. A multihit metropolis algorithm combined with an over-relaxation method is used in the updating and the conjugate gradient method is employed for Dirac matrix inversion. Configurations are stored every 1000 sweeps.« less

Hadron spectrum of quenched QCD on a 32[sup 3] [times] 64 lattice

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Seyong; Sinclair, D.K.

1992-10-01

Preliminary results from a hadron spectrum calculation of quenched Quantumchromodynamics on a 32[sup 3] [times] 64 lattice at [beta] = 6.5 are reported. The hadron spectrum calculation is done with staggered quarks of masses, m[sub q]a = 0.001, 0.005 and 0.0025. We use two different sources in order to be able to extract the [Delta] mass in addition to the usual local light hadron masses. The numerical simulation is executed on the Intel Touchstone Delta computer. The peak speed of the Delta for a 16 [times] 32 mesh configuration is 41 Gflops for 32 bit precision. The sustained speed formore » our updating code is 9.5 Gflops. A multihit metropolis algorithm combined with an over-relaxation method is used in the updating and the conjugate gradient method is employed for Dirac matrix inversion. Configurations are stored every 1000 sweeps.« less

Four-body decays of B meson with lepton number violation

NASA Astrophysics Data System (ADS)

Yuan, Han; Wang, Tianhong; Jiang, Yue; Li, Qiang; Wang, Guo-Li

2018-06-01

The existence of heavy meson lepton number violating (LNV) processes shows the Majorana nature of the neutrino. Much of this theoretical and experimental researche focuses on this type of decay. Four-body epton-number violation (LNV) processes of the B meson may have sizable branching ratios as they share the same vertex and mixing parameters with the three-body case. Mixing parameters between the heavy Majorana neutrino and charged leptons extracted from the three-body case can be used to constrain the branching ratios of four-body decays of the B meson. So we can update the upper limits of these mixing parameters with new experimental data of the three-body LNV decays. We also analyze {B}0\\to {D}* -{{\\ell }}1+{{\\ell }}2+{M}2- using the updated parameters and estimate some channels’ reconstruction events using current experimental data from Belle.

Update on Heavy-Meson Spectrum Tests of the Oktay--Kronfeld Action

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bailey, Jon A.; Jang, Yong-Chull; Lee, Weonjong

2016-01-18

We present updated results of a numerical improvement test with heavy-meson spectrum for the Oktay--Kronfeld (OK) action. The OK action is an extension of the Fermilab improvement program for massive Wilson fermions including all dimension-six and some dimension-seven bilinear terms. Improvement terms are truncated by HQET power counting atmore » $$\\mathrm{O}(\\Lambda^3/m_Q^3)$$ for heavy-light systems, and by NRQCD power counting at $$\\mathrm{O}(v^6)$$ for quarkonium. They suffice for tree-level matching to QCD to the given order in the power-counting schemes. To assess the improvement, we generate new data with the OK and Fermilab action that covers both charm and bottom quark mass regions on a MILC coarse $$(a \\approx 0.12~\\text{fm})$$ $2+1$ flavor, asqtad-staggered ensemble. We update the analyses of the inconsistency quantity and the hyperfine splittings for the rest and kinetic masses. With one exception, the results clearly show that the OK action significantly reduces heavy-quark discretization effects in the meson spectrum. The exception is the hyperfine splitting of the heavy-light system near the $$B_s$$ meson mass, where statistics are too low to draw a firm conclusion, despite promising results.« less

Parabolic Trough Collector Cost Update for the System Advisor Model (SAM)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurup, Parthiv; Turchi, Craig S.

2015-11-01

This report updates the baseline cost for parabolic trough solar fields in the United States within NREL's System Advisor Model (SAM). SAM, available at no cost at https://sam.nrel.gov/, is a performance and financial model designed to facilitate decision making for people involved in the renewable energy industry. SAM is the primary tool used by NREL and the U.S. Department of Energy (DOE) for estimating the performance and cost of concentrating solar power (CSP) technologies and projects. The study performed a bottom-up build and cost estimate for two state-of-the-art parabolic trough designs -- the SkyTrough and the Ultimate Trough. The SkyTroughmore » analysis estimated the potential installed cost for a solar field of 1500 SCAs as $170/m 2 +/- $6/m 2. The investigation found that SkyTrough installed costs were sensitive to factors such as raw aluminum alloy cost and production volume. For example, in the case of the SkyTrough, the installed cost would rise to nearly $210/m 2 if the aluminum alloy cost was $1.70/lb instead of $1.03/lb. Accordingly, one must be aware of fluctuations in the relevant commodities markets to track system cost over time. The estimated installed cost for the Ultimate Trough was only slightly higher at $178/m 2, which includes an assembly facility of $11.6 million amortized over the required production volume. Considering the size and overall cost of a 700 SCA Ultimate Trough solar field, two parallel production lines in a fully covered assembly facility, each with the specific torque box, module and mirror jigs, would be justified for a full CSP plant.« less

The distribution of the bats of South Carolina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Menzel, Jennifer M.; Menzel, Michael A.; Ford, W. Mark

Menzel. J.M., M.A. Menzel, W.M. Ford, J.W. Edwards, S.R. Sheffield, J.C. Kilgo, and M.S. Bunch. 2003. The distribution of the bats of South Carolina. Southeastern Nat. 2(1): 121-152. There is a paucity of information available about the distribution of bats in the southeastern United States. We synthesized records from museums, bat captures, and bats submitted for rabies testing to provide a more accurate and useful distribution for natural resource managers and those planning to research bats in South Carolina. Distributional information, including maps, collection localities within counties, and literature references, for all 14 species of bats that occur in Southmore » Carolina, has never been synthesized. To provide better information on the state's bat fauna, we have updated distributions for all species that occur in South Carolina.« less

Update rules and interevent time distributions: slow ordering versus no ordering in the voter model.

PubMed

Fernández-Gracia, J; Eguíluz, V M; San Miguel, M

2011-07-01

We introduce a general methodology of update rules accounting for arbitrary interevent time (IET) distributions in simulations of interacting agents. We consider in particular update rules that depend on the state of the agent, so that the update becomes part of the dynamical model. As an illustration we consider the voter model in fully connected, random, and scale-free networks with an activation probability inversely proportional to the time since the last action, where an action can be an update attempt (an exogenous update) or a change of state (an endogenous update). We find that in the thermodynamic limit, at variance with standard updates and the exogenous update, the system orders slowly for the endogenous update. The approach to the absorbing state is characterized by a power-law decay of the density of interfaces, observing that the mean time to reach the absorbing state might be not well defined. The IET distributions resulting from both update schemes show power-law tails.

Progress Report on the University of Arizona NGST Mirror System Demonstrator

NASA Technical Reports Server (NTRS)

Baiocchi, Dave; Burge, Jim; Cuerden, Brian; Stahl, Philip (Technical Monitor)

2002-01-01

We will present an update for the University of Arizona NGST (Next Generation Space Telescope) Mirror System Demonstrator (NMSD). The 2-m, f/5 NMSD mirror uses a 2 mm thick glass substrate and an actuated lightweight structure for surface accuracy and support. We will review the mirror's basic design and summarize the fabrication process. We will also discuss the current results from system integration and testing.

Low-Frequency Surface Backscattering Strengths Measured in the Critical Sea Test Experiments

DTIC Science & Technology

2017-01-19

Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/7160--17-9702 Low-Frequency Surface Backscattering Strengths Measured in the Critical Sea ...LIMITATION OF ABSTRACT Low-Frequency Surface Backscattering Strengths Measured in the Critical Sea Test Experiments Roger C. Gauss1 and Joseph M...significantly- updated results from 55 broadband SUS SSS measurements in 6 Critical Sea Test (CST) experiments. Since the time of the previously

Model-Based Compositional Reasoning for Complex Systems of Systems (SoS)

DTIC Science & Technology

2016-11-01

more structured approach for finding flaws /weaknesses in the systems . As the system is updated, either in response to a found flaw or new...AFRL-RQ-WP-TR-2016-0172 MODEL-BASED COMPOSITIONAL REASONING FOR COMPLEX SYSTEMS OF SYSTEMS (SoS) M. Anthony Aiello, Benjamin D. Rodes...LABORATORY AEROSPACE SYSTEMS DIRECTORATE WRIGHT-PATTERSON AIR FORCE BASE, OH 45433-7541 AIR FORCE MATERIEL COMMAND UNITED STATES AIR FORCE NOTICE

Potential Misclassification of Urinary Tract-Related Bacteremia Upon Applying the 2015 Catheter-Associated Urinary Tract Infection Surveillance Definition From the National Healthcare Safety Network.

PubMed

Greene, M Todd; Ratz, David; Meddings, Jennifer; Fakih, Mohamad G; Saint, Sanjay

2016-04-01

The Centers for Disease Control and Prevention recently updated the surveillance definition of catheter-associated urinary tract infection to include only urine culture bacteria of at least 1 × 10(5) colony-forming units/mL. Our findings suggest that the new surveillance definition may fail to capture clinically meaningful catheter-associated urinary tract infections.

Spent nuclear fuel canister storage building conceptual design report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swenson, C.E.

This Conceptual Design Report provides the technical basis for the Spent Nuclear Fuels Project, Canister Storage Building, and as amended by letter (correspondence number 9555700, M.E. Witherspoon to E.B. Sellers, ``Technical Baseline and Updated Cost Estimate for the Canister Storage Building``, dated October 24, 1995), includes the project cost baseline and Criteria to be used as the basis for starting detailed design in fiscal year 1995.

The Development of Methodologies for Determining Non-Linear Effects in Infrasound Sensors

DTIC Science & Technology

2010-09-01

THE DEVELOPMENT OF METHODOLOGIES FOR DETERMINING NON-LINEAR EFFECTS IN INFRASOUND SENSORS Darren M. Hart, Harold V. Parks, and Randy K. Rembold...the past year, four new infrasound sensor designs were evaluated for common performance characteristics, i.e., power consumption, response (amplitude...and phase), noise, full-scale, and dynamic range. In the process of evaluating a fifth infrasound sensor, which is an update of an original design

Brief Report: Preliminary Evaluation of the Theory of Mind Inventory and Its Relationship to Measures of Social Skills

ERIC Educational Resources Information Center

Lerner, Matthew D.; Hutchins, Tiffany L.; Prelock, Patricia A.

2011-01-01

This study presents updated information on a parent-report measure of Theory of Mind (ToM), formerly called the Perception of Children's Theory of Mind Measure (Hutchins et al., "J Autism Dev Disord" 38:143-155, 2008), renamed the Theory of Mind Inventory (ToMI), for use with parents of children with autism spectrum disorder (ASD). This study…

Recent and past Saharan dust deposition in the Carpathian Basin and its possible effects on interglacial soil formation

NASA Astrophysics Data System (ADS)

Varga, György

2016-04-01

Several hundred tons of windblown dust material are transported every year from Saharan dust source areas into direction of Europe, modifying important climatic and other environmental processes of distant areas. North African aerosols have been also identified several times a year in the Carpathian Basin, where under the influence of certain synoptic meteorological conditions Saharan dust accumulation can clearly be observed. Previous satellite based studies were suitable to estimate the frequency and magnitude of Saharan dust episodes in the investigation area, however, the assessment of North African dust deposition can be done with model simulations. In this study, calculations were made by using the data of BSC-DREAM8b (Barcelona Supercomputing Center's Dust REgional Atmospheric Model) v1.0 and v2.0 database. Simulation results of the BSC-DREAM8b v1.0 are available from 1 January 2000 to 31 December 2012, while the results of the updated v2.0 calculations are ready for the period between 1 January 2006 and 31 December 2014. BSC DREAM8b v1.0 model simulations for the period between 2000 and 2012 provided an annual mean of 0.0285 g/m2/y dry and 0.034 g/m2/y wet deposition values in the Carpathian Basin, which is equivalent to a total of 0.0636 g/m2/y. The updated v2.0 version for the period of 2006-2014 gave significantly larger values: 0.133 g/m2/y dry; 0.085 g/m2/y wet and 0.219 g/m2/y total annual dust deposition. By comparing the results of the overlapping period between 2006 and 2012 of the v1.0 and v2.0 simulations, the updated depositional scheme of the newer version provided ˜3.7-fold values in case of dry deposition and ˜1.9-fold increase in results of the wet deposition. Information available from individual events showed that the simulated wet and dry dust deposition rates are significantly underestimated. This is also suggested by previous model calculations which reported values between 5 and 10 g/m2/y for modern dust flux in the investigated area. According to our deposition adjustment estimations the annual amount of deposited Saharan dust can be set into the range between 3 and 5 g/m2/y. This study is also aimed at providing an estimate on the Saharan dust sedimentation in past interglacials based on stratigraphic and sedimentary data of loess-paleosoil sequences and by using the values of recent dust accumulation simulations. The possible influence of accumulated aeolian material on soil properties and on paleoenvironmental interpretation of paleosoils (modified by syngenetic, external dust addition) will also be discussed. Support of the Hungarian Research Fund OTKA under contract PD108708 (for G. Varga) is gratefully acknowledged. It was additionally supported (for G. Varga) by the Bolyai János Research Scholarship of the Hungarian Academy of Sciences.

Seafood workers and respiratory disease: an update.

PubMed

Jeebhay, Mohamed F; Cartier, André

2010-04-01

This review focuses on seafood workers engaged in harvesting, processing and food preparation. These groups are increasingly at risk of developing occupational allergy and respiratory disease as a result of seafood handling and processing activities. This review provides an update of a previous review conducted a decade ago. Exposure characterization studies have demonstrated that aerosolization of seafood (muscle, visceral organs, skin/mucin) during canning and fishmeal operations result in highly variable levels of airborne particulate (0.001-11.293 mg/m3) and allergens (0.001-75.748 ug/m3). Occupational asthma is more commonly associated with shellfish (4-36%) than with bony fish (2-8%). Other seafood-associated biological (Anisakis) and chemical agents (protease enzymes, toxins and preservatives) have also been implicated. Atopy, smoking and level of exposure to allergens are significant risk factors for sensitization and the development of occupational asthma. Molecular studies of the allergens suggest that aside from tropomyosin and parvalbumin, other as yet uncharacterized allergens are important. Future research needs to focus on detailed characterization of allergens in order to standardize exposure assessment techniques, which are key to assessing the impact of interventions. The clinical relevance of agents such as serine proteases and endotoxins in causing asthma through nonallergic mechanisms needs further epidemiological investigation.

VisNAV 100: a robust, compact imaging sensor for enabling autonomous air-to-air refueling of aircraft and unmanned aerial vehicles

NASA Astrophysics Data System (ADS)

Katake, Anup; Choi, Heeyoul

2010-01-01

To enable autonomous air-to-refueling of manned and unmanned vehicles a robust high speed relative navigation sensor capable of proving high accuracy 3DOF information in diverse operating conditions is required. To help address this problem, StarVision Technologies Inc. has been developing a compact, high update rate (100Hz), wide field-of-view (90deg) direction and range estimation imaging sensor called VisNAV 100. The sensor is fully autonomous requiring no communication from the tanker aircraft and contains high reliability embedded avionics to provide range, azimuth, elevation (3 degrees of freedom solution 3DOF) and closing speed relative to the tanker aircraft. The sensor is capable of providing 3DOF with an error of 1% in range and 0.1deg in azimuth/elevation up to a range of 30m and 1 deg error in direction for ranges up to 200m at 100Hz update rates. In this paper we will discuss the algorithms that were developed in-house to enable robust beacon pattern detection, outlier rejection and 3DOF estimation in adverse conditions and present the results of several outdoor tests. Results from the long range single beacon detection tests will also be discussed.

Relativistic tests with lunar laser ranging

NASA Astrophysics Data System (ADS)

Hofmann, F.; Müller, J.

2018-02-01

This paper presents the recent version of the lunar laser ranging (LLR) analysis model at the Institut für Erdmessung (IfE), Leibniz Universität Hannover and highlights a few tests of Einstein’s theory of gravitation using LLR data. Investigations related to a possible temporal variation of the gravitational constant, the equivalence principle, the PPN parameters β and γ as well as the geodetic precession were carried out. The LLR analysis model was updated by gravitational effects of the Sun and planets with the Moon as extended body. The higher-order gravitational interaction between Earth and Moon as well as effects of the solid Earth tides on the lunar motion were refined. The basis for the modeled lunar rotation is now a 2-layer core/mantle model according to the DE430 ephemeris. The validity of Einstein’s theory was studied using this updated analysis model and an LLR data set from 1970 to January 2015. Within the estimated accuracies, no deviations from Einstein’s theory are detected. A relative temporal variation of the gravitational constant is estimated as \\dot{G}/G_0=(7.1+/-7.6)×10-14~yr-1 , the test of the equivalence principle gives Δ(m_g/m_i)EM=(-3+/-5)×10-14 and the Nordtvedt parameter \

Reexamination of Total Fluid Intake and Bladder Cancer in the Health Professionals Follow-Up Study Cohort

PubMed Central

Zhou, Jiachen; Smith, Scott; Giovannucci, Edward; Michaud, Dominique S.

2012-01-01

It has been hypothesized that high fluid intake may reduce contact time between carcinogens and bladder epithelium and consequently reduce carcinogenesis. Epidemiologic studies examining fluid intake and bladder cancer have been extremely inconsistent, ranging from strong inverse to strong positive associations. The authors reevaluated the association between fluid intake and bladder cancer among 47,909 participants in the prospective Health Professionals Follow-up Study over a period of 22 years. During follow-up (1986–2008), 823 incident bladder cancer cases were diagnosed. Information on fluid intake was collected by using the food frequency questionnaire at baseline and every 4 years thereafter. Cox proportional hazard regression analysis was used to adjust for risk factors for bladder cancer. Total fluid intake was inversely associated with bladder cancer when the analysis was based on the baseline diet (relative risk = 0.76, 95% confidence interval: 0.60, 0.97), comparing the highest total daily fluid intake quintile (>2,531 mL/day) with the lowest quintile (<1,290 mL/day) (Ptrend = 0.01). However, no association was detected when the analysis was based on recent diet or cumulative updated diet. The updated analysis for total fluid intake and bladder cancer was attenuated compared with the original findings from the first 10-year follow-up period. PMID:22355034

2000 Montana state rail plan update

DOT National Transportation Integrated Search

2000-01-01

This 2000 Montana Rail Plan Update is a comprehensive update of the State Rail Plan. The purpose of this update is to review the State's role in rail planning, retain eligibility for Local Rail Freight Assistance (LRFA) funding, update the descriptio...

Timing Interactions in Social Simulations: The Voter Model

NASA Astrophysics Data System (ADS)

Fernández-Gracia, Juan; Eguíluz, Víctor M.; Miguel, Maxi San

The recent availability of huge high resolution datasets on human activities has revealed the heavy-tailed nature of the interevent time distributions. In social simulations of interacting agents the standard approach has been to use Poisson processes to update the state of the agents, which gives rise to very homogeneous activity patterns with a well defined characteristic interevent time. As a paradigmatic opinion model we investigate the voter model and review the standard update rules and propose two new update rules which are able to account for heterogeneous activity patterns. For the new update rules each node gets updated with a probability that depends on the time since the last event of the node, where an event can be an update attempt (exogenous update) or a change of state (endogenous update). We find that both update rules can give rise to power law interevent time distributions, although the endogenous one more robustly. Apart from that for the exogenous update rule and the standard update rules the voter model does not reach consensus in the infinite size limit, while for the endogenous update there exist a coarsening process that drives the system toward consensus configurations.

Fishes of the hadal zone including new species, in situ observations and depth records of Liparidae

NASA Astrophysics Data System (ADS)

Linley, Thomas D.; Gerringer, Mackenzie E.; Yancey, Paul H.; Drazen, Jeffrey C.; Weinstock, Chloe L.; Jamieson, Alan J.

2016-08-01

Observations and records for fish exceeding 6000 m deep are few and often spurious. Recent developments in accessing and sampling the hadal zone 6000-11,000 m) have led to an acceleration in new findings in the deep subduction trenches, particularly in the Pacific Ocean. This study describes the discovery of two new species of snailfish (Liparidae) from the Mariana Trench; the 'Mariana snailfish' (6198-8076 m) and the 'Ethereal snailfish' (7939-8145 m). These new findings represent respectively the deepest known specimen caught with corroborating depth data, and the deepest fish seen alive. Further specimens and observations of the Kermadec Trench snailfish, Notoliparis kermadecensis, are also presented, as well as the first hadal records of Synaphobranchidae and Zoarcidae (6068 and 6145 m respectively) and a depth extension for the Macrouridae (maximum depth now 7012 m). Details of these new snailfish specimens caught by baited trap and behaviour observations filmed by baited cameras are presented. An updated assessment of fishes from hadal depths is also reported.

Comprehensive update of dalbavancin activity when tested against uncommonly isolated streptococci, Corynebacterium spp., Listeria monocytogenes, and Micrococcus spp. (1357 strains).

PubMed

Jones, Ronald N; Stilwell, Matthew G

2013-06-01

Dalbavancin is an investigational lipoglycopeptide having an extended serum elimination half-life allowing once-weekly dosing. Data from testing 1357 strains of uncommonly isolated species expand the dalbavancin spectrum details as follows (MIC50/90): β-haemolytic streptococcal serogroups C, F, and G (≤0.03/≤0.03 μg/mL), 7 viridans group of streptococci (≤0.03/≤0.03-0.06 μg/mL), 5 Corynebacterium spp. (0.06/0.12 μg/mL), Listeria monocytogenes (0.06/0.12 μg/mL), and Micrococcus spp. (≤0.03/≤0.03 μg/mL). Among all reported isolates, 99.8% of tested strains were inhibited at dalbavancin MIC values at ≤0.12 μg/mL. Dalbavancin remains very potent against rarer Gram-positive pathogens, using in vitro test experience with organisms cultured through 2011. Copyright © 2013 Elsevier Inc. All rights reserved.

Time to Update and Quantitative Changes in the Results of Cochrane Pregnancy and Childbirth Reviews

PubMed Central

Jaidee, Wanlop; Moher, David; Laopaiboon, Malinee

2010-01-01

Background The recommended interval between updates for systematic reviews included in The Cochrane Library is 2 years. However, it is unclear whether this interval is always appropriate. Whereas excessive updating wastes time and resources, insufficient updating allows out-of-date or incomplete evidence to guide clinical decision-making. We set out to determine, for Cochrane pregnancy and childbirth reviews, the frequency of updates, factors associated with updating, and whether updating frequency was appropriate. Methodology/Principal Findings Cochrane pregnancy and childbirth reviews published in Issue 3, 2007 of the Cochrane Database of Systematic Reviews were retrieved, and data were collected from their original and updated versions. Quantitative changes were determined for one of the primary outcomes (mortality, or the outcome of greatest clinical significance). Potential factors associated with time to update were assessed using the Cox proportional hazard model. Among the 101 reviews in our final sample, the median time before the first update was 3.3 years (95% CI 2.7–3.8). Only 32.7% had been updated within the recommended interval of 2 years. In 75.3% (76/101), a median of 3 new trials with a median of 576 additional participants were included in the updated versions. There were quantitative changes in 71% of the reviews that included new trials (54/76): the median change in effect size was 18.2%, and the median change in 95% CI width was 30.8%. Statistical significance changed in 18.5% (10/54) of these reviews, but conclusions were revised in only 3.7% (2/54). A shorter time to update was associated with the same original review team at updating. Conclusions/Significance Most reviews were updated less frequently than recommended by Cochrane policy, but few updates had revised conclusions. Prescribed time to update should be reconsidered to support improved decision-making while making efficient use of limited resources. PMID:20644625

Useful References in Pediatric Cardiac Intensive Care: The 2017 Update.

PubMed

Uzark, Karen C; Costello, John M; DeSena, Holly C; Thiagajaran, Ravi; Smith-Parrish, Melissa; Gist, Katja M

2018-03-10

Pediatric cardiac intensive care continues to evolve, with rapid advances in knowledge and improvement in clinical outcomes. In the past, the Board of Directors of the Pediatric Cardiac Intensive Care Society created and subsequently updated a list of sentinel references focused on the care of critically ill children with congenital and acquired heart disease. The objective of this article is to provide clinicians with a compilation and brief summary of updated and useful references that have been published since 2012. Pediatric Cardiac Intensive Care Society members were solicited via a survey sent out between March 20, 2017, and April 28, 2017, to provide important references that have impacted clinical care. The survey was sent to approximately 523 members. Responses were received from 45 members, of which some included multiple references. Following review of the list of references, and removing editorials, references were compiled by the first and last author. The final list was submitted to members of the society's Research Briefs Committee, who ranked each publication. Rankings were compiled and the references with the highest scores included. Research Briefs Committee members ranked the articles from 1 to 3, with one being highly relevant and should be included and 3 being less important and should be excluded. Averages were computed, and the top articles included in this article. The first (K.C.U.) and last author (K.M.G.) reviewed and developed summaries of each article. This article contains a compilation of useful references for the critical care of children with congenital and acquired heart disease published in the last 5 years. In conjunction with the prior version of this update in 2012, this article may be used as an educational reference in pediatric cardiac intensive care.

NSLS II Vacuum System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferreira, M.; Doom, L.; Hseuh, H.

2009-09-13

National Synchrotron Light Source II, being constructed at Brookhaven, is a 3-GeV, 500 mA, 3rd generation synchrotron radiation facility with ultra low emittance electron beams. The storage ring vacuum system has a circumference of 792 m and consists of over 250 vacuum chambers with a simulated average operating pressure of less than 1 x 10{sup -9} mbar. A summary of the update design of the vacuum system including girder supports of the chambers, gauges, vacuum pumps, bellows, beam position monitors and simulation of the average pressure will be shown. A brief description of the techniques and procedures for cleaning andmore » mounting the chambers are given.« less

M4FT-16LL080302052-Update to Thermodynamic Database Development and Sorption Database Integration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zavarin, Mavrik; Wolery, T. J.; Atkins-Duffin, C.

2016-08-16

This progress report (Level 4 Milestone Number M4FT-16LL080302052) summarizes research conducted at Lawrence Livermore National Laboratory (LLNL) within the Argillite Disposal R&D Work Package Number FT-16LL08030205. The focus of this research is the thermodynamic modeling of Engineered Barrier System (EBS) materials and properties and development of thermodynamic databases and models to evaluate the stability of EBS materials and their interactions with fluids at various physico-chemical conditions relevant to subsurface repository environments. The development and implementation of equilibrium thermodynamic models are intended to describe chemical and physical processes such as solubility, sorption, and diffusion.

Update on Risk Reduction Activities for a Liquid Advanced Booster for NASA's Space Launch System

NASA Technical Reports Server (NTRS)

Crocker, Andy; Greene, William D.

2017-01-01

Goals of NASA's Advanced Booster Engineering Demonstration and/or Risk Reduction (ABEDRR) are to: (1) Reduce risks leading to an affordable Advanced Booster that meets the evolved capabilities of SLS. (2) Enable competition by mitigating targeted Advanced Booster risks to enhance SLS affordability. SLS Block 1 vehicle is being designed to carry 70 mT to LEO: (1) Uses two five-segment solid rocket boosters (SRBs) similar to the boosters that helped power the space shuttle to orbit. Evolved 130 mT payload class rocket requires an advanced booster with more thrust than any existing U.S. liquid-or solid-fueled boosters

Oxygen potentials, oxygen diffusion coefficients and defect equilibria of nonstoichiometric (U,Pu)O2±x

NASA Astrophysics Data System (ADS)

Kato, Masato; Watanabe, Masashi; Matsumoto, Taku; Hirooka, Shun; Akashi, Masatoshi

2017-04-01

Oxygen potential of (U,Pu)O2±x was evaluated based on defect chemistry using an updated experimental data set. The relationship between oxygen partial pressure and deviation x in (U,Pu)O2±x was analyzed, and equilibrium constants of defect formation were determined as functions of Pu content and temperature. Brouwer's diagrams were constructed using the determined equilibrium constants, and a relational equation to determine O/M ratio was derived as functions of O/M ratio, Pu content and temperature. In addition, relationship between oxygen potential and oxygen diffusion coefficients were described.

Technical Note: spektr 3.0—A computational tool for x-ray spectrum modeling and analysis

PubMed Central

Punnoose, J.; Xu, J.; Sisniega, A.; Zbijewski, W.; Siewerdsen, J. H.

2016-01-01

Purpose: A computational toolkit (spektr 3.0) has been developed to calculate x-ray spectra based on the tungsten anode spectral model using interpolating cubic splines (TASMICS) algorithm, updating previous work based on the tungsten anode spectral model using interpolating polynomials (TASMIP) spectral model. The toolkit includes a matlab (The Mathworks, Natick, MA) function library and improved user interface (UI) along with an optimization algorithm to match calculated beam quality with measurements. Methods: The spektr code generates x-ray spectra (photons/mm2/mAs at 100 cm from the source) using TASMICS as default (with TASMIP as an option) in 1 keV energy bins over beam energies 20–150 kV, extensible to 640 kV using the TASMICS spectra. An optimization tool was implemented to compute the added filtration (Al and W) that provides a best match between calculated and measured x-ray tube output (mGy/mAs or mR/mAs) for individual x-ray tubes that may differ from that assumed in TASMICS or TASMIP and to account for factors such as anode angle. Results: The median percent difference in photon counts for a TASMICS and TASMIP spectrum was 4.15% for tube potentials in the range 30–140 kV with the largest percentage difference arising in the low and high energy bins due to measurement errors in the empirically based TASMIP model and inaccurate polynomial fitting. The optimization tool reported a close agreement between measured and calculated spectra with a Pearson coefficient of 0.98. Conclusions: The computational toolkit, spektr, has been updated to version 3.0, validated against measurements and existing models, and made available as open source code. Video tutorials for the spektr function library, UI, and optimization tool are available. PMID:27487888

Technical Note: SPEKTR 3.0—A computational tool for x-ray spectrum modeling and analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Punnoose, J.; Xu, J.; Sisniega, A.

2016-08-15

Purpose: A computational toolkit (SPEKTR 3.0) has been developed to calculate x-ray spectra based on the tungsten anode spectral model using interpolating cubic splines (TASMICS) algorithm, updating previous work based on the tungsten anode spectral model using interpolating polynomials (TASMIP) spectral model. The toolkit includes a MATLAB (The Mathworks, Natick, MA) function library and improved user interface (UI) along with an optimization algorithm to match calculated beam quality with measurements. Methods: The SPEKTR code generates x-ray spectra (photons/mm{sup 2}/mAs at 100 cm from the source) using TASMICS as default (with TASMIP as an option) in 1 keV energy bins overmore » beam energies 20–150 kV, extensible to 640 kV using the TASMICS spectra. An optimization tool was implemented to compute the added filtration (Al and W) that provides a best match between calculated and measured x-ray tube output (mGy/mAs or mR/mAs) for individual x-ray tubes that may differ from that assumed in TASMICS or TASMIP and to account for factors such as anode angle. Results: The median percent difference in photon counts for a TASMICS and TASMIP spectrum was 4.15% for tube potentials in the range 30–140 kV with the largest percentage difference arising in the low and high energy bins due to measurement errors in the empirically based TASMIP model and inaccurate polynomial fitting. The optimization tool reported a close agreement between measured and calculated spectra with a Pearson coefficient of 0.98. Conclusions: The computational toolkit, SPEKTR, has been updated to version 3.0, validated against measurements and existing models, and made available as open source code. Video tutorials for the SPEKTR function library, UI, and optimization tool are available.« less

Source Update Capture in Information Agents

NASA Technical Reports Server (NTRS)

Ashish, Naveen; Kulkarni, Deepak; Wang, Yao

2003-01-01

In this paper we present strategies for successfully capturing updates at Web sources. Web-based information agents provide integrated access to autonomous Web sources that can get updated. For many information agent applications we are interested in knowing when a Web source to which the application provides access, has been updated. We may also be interested in capturing all the updates at a Web source over a period of time i.e., detecting the updates and, for each update retrieving and storing the new version of data. Previous work on update and change detection by polling does not adequately address this problem. We present strategies for intelligently polling a Web source for efficiently capturing changes at the source.

Situation Model Updating in Young and Older Adults: Global versus Incremental Mechanisms

PubMed Central

Bailey, Heather R.; Zacks, Jeffrey M.

2015-01-01

Readers construct mental models of situations described by text. Activity in narrative text is dynamic, so readers must frequently update their situation models when dimensions of the situation change. Updating can be incremental, such that a change leads to updating just the dimension that changed, or global, such that the entire model is updated. Here, we asked whether older and young adults make differential use of incremental and global updating. Participants read narratives containing changes in characters and spatial location and responded to recognition probes throughout the texts. Responses were slower when probes followed a change, suggesting that situation models were updated at changes. When either dimension changed, responses to probes for both dimensions were slowed; this provides evidence for global updating. Moreover, older adults showed stronger evidence of global updating than did young adults. One possibility is that older adults perform more global updating to offset reduced ability to manipulate information in working memory. PMID:25938248

20th Annual Systems Engineering Conference. Volume 3, Thursday

DTIC Science & Technology

2017-10-26

Assurance Center (JFAC) 2017 Update u Mr. Thomas Hurt, Department of Defense 4B1 Tr a c k 2 m il le r Education & Training 19813 Shaping the...k s a n d r a M a r k i n a - K h u s i d amk@mitre.org D r. R ya n J a c o b s r j a c o b s @mitre.org October 2017 NDIA 20th Annual Systems...A n t u l lantul@mitre.org D r. A l e k s a n d r a M a r k i n a - K h u s i d amk@mitre.org D r. R y a n J a c o b s rjacobs@mitre.org J a

Working Memory Updating as a Predictor of Academic Attainment

ERIC Educational Resources Information Center

Lechuga, M. Teresa; Pelegrina, Santiago; Pelaez, Jose L.; Martin-Puga, M. Eva; Justicia, M. Jose

2016-01-01

There is growing evidence supporting the importance of executive functions, and specifically working memory updating (WMU), for children's academic achievement. This study aimed to assess the specific contribution of updating to the prediction of academic performance. Two updating tasks, which included different updating components, were…

Targeting striatal metabotropic glutamate receptor type 5 in Parkinson's disease: bridging molecular studies and clinical trials.

PubMed

Vallano, A; Fernandez-Duenas, V; Garcia-Negredo, G; Quijada, M A; Simon, C P; Cuffí, M L; Carbonell, L; Sanchez, S; Arnau, J M; Ciruela, F

2013-12-01

Metabotropic glutamate (mGlu) receptors are G protein-coupled receptors expressed primarily on neurons and glial cells modulating the effects of glutamatergic neurotransmission. The pharmacological manipulation of these receptors has been postulated to be valuable in the management of some neurological disorders. Accordingly, the targeting of mGlu5 receptors as a therapeutic approach for Parkinson's disease (PD) has been proposed, especially to manage the adverse symptoms associated to chronic treatment with classical PD drugs. Thus, the specific pharmacological blocking of mGlu5 receptors constitutes one of the most attractive non-dopaminergic-based strategies for PD management in general and for the L-DOPA-induced dyskinesia (LID) in particular. Overall, we provide here an update of the current state of the art of these mGlu5 receptor-based approaches that are under clinical study as agents devoted to alleviate PD symptoms.

NASA/Cousteau ocean bathymetry experiment. Remote bathymetry using high gain LANDSAT data

NASA Technical Reports Server (NTRS)

Polcyn, F. C.

1976-01-01

Satellite remote bathymetry was varified to 22 m depths where water clarity was defined by alpha = .058 1/m and bottom reflection, r(b), was 26%. High gain band 4 and band 5 CCT data from LANDSAT 1 was used for a test site in the Bahama Islands and near Florida. Near Florida where alpha = .11 1/m and r(b) = 20%, depths to 10 m were verified. Depth accuracies within 10% rms were achieved. Position accuracies within one LANDSAT pixel were obtained by reference to the Transit navigation satellites. The Calypso and the Beayondan, two ships, were at anchor on each of the seven days during LANDSAT 1 and 2 overpasses: LORAN C position information was used when the ships were underway making depth transects. Results are expected to be useful for updating charts showing shoals hazardous to navigation or in monitoring changes in nearshore topography.

First Zenith Total Delay and Integrated Water Vapour Estimates from the Near Real-Time GNSS Data Processing Systems at the University of Luxembourg

NASA Astrophysics Data System (ADS)

Ahmed, F.; Teferle, F. N.; Bingley, R. M.

2012-04-01

Since September 2011 the University of Luxembourg in collaboration with the University of Nottingham has been setting up two near real-time processing systems for ground-based GNSS data for the provision of zenith total delay (ZTD) and integrated water vapour (IWV) estimates. Both systems are based on Bernese v5.0, use the double-differenced network processing strategy and operate with a 1-hour (NRT1h) and 15-minutes (NRT15m) update cycle. Furthermore, the systems follow the approach of the E-GVAP METO and IES2 systems in that the normal equations for the latest data are combined with those from the previous four updates during the estimation of the ZTDs. NRT1h currently takes the hourly data from over 130 GNSS stations in Europe whereas NRT15m is primarily using the real-time streams of EUREF-IP. Both networks include additional GNSS stations in Luxembourg, Belgium and France. The a priori station coordinates for all of these stem from a moving average computed over the last 20 to 50 days and are based on the precise point positioning processing strategy. In this study we present the first ZTD and IWV estimates obtained from the NRT1h and NRT15m systems in development at the University of Luxembourg. In a preliminary evaluation we compare their performance to the IES2 system at the University of Nottingham and find the IWV estimates to agree at the sub-millimetre level.

Quantifying Shoreline Change on Oahu, Hawaii using Aerial Orthophotogrammetry in a Regime of Rising Sea-level

NASA Astrophysics Data System (ADS)

Over, J. S. R.; Fletcher, C. H., II; Barbee, M.; Anderson, T. R.

2016-12-01

Shoreline change data has become a significant coastal management tool in the effort to protect beaches for recreation, tourism, and environmental conservation. The Hawaii Shoreline Study uses historical aerial photographs (1928-2006) to delineate long-term trends of coastal accretion and erosion. Data are provided to public and government partners to assist with coastal zone management. In a preliminary effort to update the database for Oahu, aerial images taken in 2015 along the coasts at Makalii, Waikiki, and Sunset Beach, were orthorectified and mosaicked at 0.5 m resolution in PCI Geomatica Orthoengine. Changes in the position of the shoreline were mapped across 478 shore-perpendicular transects (spaced 20 m alongshore) using the low water mark as a shoreline proxy. Analysis of shoreline movement reveals localized variation in rates of change controlled by, but not limited to, differences in wave regimes, armoring, sea level rise, and fluctuations in sediment availability. Updated rates have a mean of -0.073 ± 0.07 m/yr, an indication that they are roughly stable. However, distinct patterns emerge locally. Erosion dominated the period between 2006 and 2015, where 53% of transects lost beach width, 37% showed accretion, and 10% did not change. Sunset Beach and Makalii saw (resp.) 12% and 24% increases in new construction on beachfront parcels in areas with known erosion regimes. These results warrant continued assessment of shoreline change to (1) monitor vulnerability to erosion; likely a result of long-term sea level rise, and (2) improve understanding of localized processes driving erosion and accretion.

Wide Swath Stereo Mapping from Gaofen-1 Wide-Field-View (WFV) Images Using Calibration

PubMed Central

Chen, Shoubin; Liu, Jingbin; Huang, Wenchao

2018-01-01

The development of Earth observation systems has changed the nature of survey and mapping products, as well as the methods for updating maps. Among optical satellite mapping methods, the multiline array stereo and agile stereo modes are the most common methods for acquiring stereo images. However, differences in temporal resolution and spatial coverage limit their application. In terms of this issue, our study takes advantage of the wide spatial coverage and high revisit frequencies of wide swath images and aims at verifying the feasibility of stereo mapping with the wide swath stereo mode and reaching a reliable stereo accuracy level using calibration. In contrast with classic stereo modes, the wide swath stereo mode is characterized by both a wide spatial coverage and high-temporal resolution and is capable of obtaining a wide range of stereo images over a short period. In this study, Gaofen-1 (GF-1) wide-field-view (WFV) images, with total imaging widths of 800 km, multispectral resolutions of 16 m and revisit periods of four days, are used for wide swath stereo mapping. To acquire a high-accuracy digital surface model (DSM), the nonlinear system distortion in the GF-1 WFV images is detected and compensated for in advance. The elevation accuracy of the wide swath stereo mode of the GF-1 WFV images can be improved from 103 m to 30 m for a DSM with proper calibration, meeting the demands for 1:250,000 scale mapping and rapid topographic map updates and showing improved efficacy for satellite imaging. PMID:29494540

10 CFR 72.70 - Safety analysis report updating.

Code of Federal Regulations, 2011 CFR

2011-01-01

... original FSAR or, as appropriate, the last update to the FSAR under this section. The update shall include... for an ISFSI or MRS shall update periodically, as provided in paragraphs (b) and (c) of this section... applicant commitments developed during the license approval and/or hearing process. (b) Each update shall...

10 CFR 72.70 - Safety analysis report updating.

Code of Federal Regulations, 2014 CFR

2014-01-01

... original FSAR or, as appropriate, the last update to the FSAR under this section. The update shall include... for an ISFSI or MRS shall update periodically, as provided in paragraphs (b) and (c) of this section... applicant commitments developed during the license approval and/or hearing process. (b) Each update shall...

10 CFR 72.70 - Safety analysis report updating.

Code of Federal Regulations, 2013 CFR

2013-01-01

... original FSAR or, as appropriate, the last update to the FSAR under this section. The update shall include... for an ISFSI or MRS shall update periodically, as provided in paragraphs (b) and (c) of this section... applicant commitments developed during the license approval and/or hearing process. (b) Each update shall...

10 CFR 72.70 - Safety analysis report updating.

Code of Federal Regulations, 2012 CFR

2012-01-01

... original FSAR or, as appropriate, the last update to the FSAR under this section. The update shall include... for an ISFSI or MRS shall update periodically, as provided in paragraphs (b) and (c) of this section... applicant commitments developed during the license approval and/or hearing process. (b) Each update shall...

49 CFR 1002.3 - Updating user fees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... updating fees. Each fee shall be updated by updating the cost components comprising the fee. Cost... direct labor costs are direct labor costs determined by the cost study set forth in Revision of Fees For... by total office costs for the Offices directly associated with user fee activity. Actual updating of...

Assessment and Optimization of Lidar Measurement Availability for Wind Turbine Control (Poster)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scholbrock, F. A.; Fleming, P.; Wright, A.

2014-02-01

Integrating Lidar to improve wind turbine controls is a potential breakthrough for reducing the cost of wind energy. By providing undisturbed wind measurements up to 400m in front of the rotor, Lidar may provide an accurate update of the turbine inflow with a preview time of several seconds. Focusing on loads, several studies have evaluated potential reductions using integrated Lidar, either by simulation or full scale field testing.

Speckle interferometry at SOAR in 2012 and 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tokovinin, Andrei; Mason, Brian D.; Hartkopf, William I., E-mail: atokovinin@ctio.noao.edu, E-mail: bdm@usno.navy.mil, E-mail: wih@usno.navy.mil

2014-05-01

We report the results of speckle runs at the 4.1 m Southern Astronomical Research telescope in 2012 and 2013. A total of 586 objects were observed. We give 699 measurements of 487 resolved binaries and upper detection limits for 112 unresolved stars. Eleven pairs (including one triple) were resolved for the first time. Orbital elements have been determined for the first time for 13 pairs; orbits of another 45 binaries are revised or updated.

Using the immune system to fight, and win, the battle against cervical cancer | Center for Cancer Research

Cancer.gov

Aricca Wallace and Christian Hinrichs, M.D., catch up like old friends each time she comes to the National Institutes of Health Clinical Center for follow-up appointments. She updates him on her two boys’ wrestling competitions and state titles. He shows her pictures of the new puppy that is terrorizing his house. So far, they’ve finished each visit with Dr. Hinrichs telling

Invited Parallel Talk: Lattice results on nucleon/roper properties

NASA Astrophysics Data System (ADS)

Lin, Huey-Wen

2009-12-01

In this proceeding, I review the attempts to calculate the Nucleon resonance (including Roper as first radially excited state of nucleon and other excited states) using lattice quantum chromodynamics (QCD). The latest preliminary results from Hadron Spectrum Collaboration (HSC) with mπ thickapprox 380 MeV are reported. The Sachs electric form factor of the proton and neutron and their transition with the Roper at large Q2 are also updated in this work.

Options for Educating Students Attending Department of Defense Schools in the United States

DTIC Science & Technology

2016-01-01

Middlemiss, Martha Brown, Stephen F. Hovanic, Joel Hansen, Frank O’Gara, Elaine Kanellis, Robert M. Brady, Claudia Shaw , Jessica Ray Huffman, Rita...could receive students. Chapter Three explains our methods and data sources for assessing options, including the business case analysis approach...account for these analyses. We also identify implementation issues and barriers for each option, based on work of previous studies with updates to

Low Back Pain: Considerations for Rotary-Wing Aircrew (Reprint)

DTIC Science & Technology

2012-12-01

1985 . Report No: DCIEM-85-R-49 . 8. Bongers PM, Hulshof CTJ, Dukstra L, Boshuizen HC . Back pain and exposure to whole body vibration...in helicopter pilots . Ergonomics 1990 ; 33 : 1007 – 26 . 9. Bovenzi M, Hulshof CT . An updated review of epidemiologic studies on the...injuries. In: LaDou J, ed. Current occupational and environmental medicine, 4th ed. New York: McGraw-Hill, Inc.; 2007 . 42. Hulshof C, van Zanten

National Insect and Disease Risk Map (NIDRM)--cutting edge software for rapid insect and disease risk model development

Treesearch

Frank J. Krist

2010-01-01

The Forest Health Technology Enterprise Team (FHTET) of the U.S. Forest Service is leading an effort to produce the next version of the National Insect and Disease Risk Map (NIDRM) for targeted release in 2011. The goal of this effort is to update spatial depictions of risk of tree mortality based on: (1) newly derived 240-m geospatial information depicting the...

Interoperable Open-Source Sensor-Net Frameworks with Sensor-Package Workbench Capabilities: Motivation, Survey of Resources, and Exploratory Results

DTIC Science & Technology

2010-06-01

Military Scenario Definition Language (MSDL) for Nontraditional Warfare Scenarios," Paper 09S- SIW -001, Proceedings of the Spring Simulation...Update to the M&S Community," Paper 09S- SIW -002, Proceedings of the Spring Simulation Interoperability Workshop, Simulation Interoperability...Multiple Simulations: An Application of the Military Scenario Definition Language (MSDL)," Paper 09S- SIW -003, Proc. of the Spring Simulation

The AMANDA neutrino telescope: Science prospects and performance at first light

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halzen, Francis

1998-02-05

We update the science prospects for the recently completed AMANDA South Pole neutrino detector. With an effective telescope area of order 10{sup 4} m{sup 2} and a threshold of {approx}50 GeV, it represents the first instrument of a new generation of high energy neutrino detectors, envisaged over 25 years ago. We describe the instrument and its performance, and map its expansion to a detector of kilometer dimension.

Titan's surface and atmosphere from Cassini/VIMS data with updated methane opacity

NASA Astrophysics Data System (ADS)

Hirtzig, M.; Bézard, B.; Coustenis, A.; Lellouch, E.; Drossart, P.; deBergh, C.; Campargue, A.; Boudon, V.; Tyuterev, V.; Rannou, P.; Cours, T.; Kassi, S.; Nikitin, A.; Wang, L.; Solomonidou, A.; Schmitt, B.; Rodriguez, S.

2012-04-01

In this paper we present an updated analysis of VIMS data in view of recent developments on the methane opacity in the 1.3-5.2 µm region, a very important parameter in simulating Titan's spectrum. We use a multi-stream radiative transfer model, benefitting from the latest methane absorption coefficients available [1], which allows us to determine more accurately the haze and surface contributions. This code is applied to Cassini/VIMS spectro-imaging data of various regions with very different spectral responses to extract information on the content of the lower atmosphere (0-200 km) as well as on the surface properties. In particular, we update the DISR aerosol model [2] for the Huygens landing site that we then adjust to fit the data for other locations on Titan's disk. Fitting VIMS data taken from 2004 to 2010 (TA to T70), around Titan's mid-latitudes (40°S-40°N), we determine the latitudinal and temporal evolution of the aerosol population, monitoring the North-South Asymmetry. While around the equinox [3] witnessed the collapse of the detached haze layer, we measure a continuous depletion of the aerosols throughout the atmosphere, although the NSA remains with a brighter northern hemisphere. Using this improved atmospheric model, we also retrieve surface albedos simultaneously for all the seven windows in the whole VIMS range for these regions, also recovering the shape of the surface albedo within each window. Eventually, we look for Titan's surface probable chemical composition, using mixtures of dark and complex hydrocarbons like bitumens and tholins, as well as bright CH4, CO2, NH3 and H2O ices of various grain sizes. [4] [1] Campargue, A. et al., (2012) Icarus, submitted. [2] Tomasko, M. et al., (2008) Planetary and Space Science, 56, 669. [3] West, R.A. et al., (2011) Geophysical Research Letters, 38, L06204. [4] Hirtzig, M. et al., (2012) Planetary and Space Science, submitted.

Differentiated thyroid cancer: A retrospective evaluation of the impact of changes to disease management guidelines on patients in South East Scotland.

PubMed

Williamson, A G; Wilmot, V; Ntala, C; Gibb, F W; Conn, B; Nixon, I J

2018-06-05

The British Thyroid Association (BTA) updated guidelines for the management of differentiated thyroid cancer (DTC) in 2014. A key update was that patients with unifocal disease >10-≤40 mm in diameter, aged <45 years and with no other risk factors could be considered for lobectomy alone. The aim of this study was to retrospectively evaluate the potential impact of these changes on the management of DTC in South East Scotland, and to analyse the characteristics of lobes now potentially considered for observation rather than resection. Consecutive patients were identified through prospectively held regional MDT minutes from 2009 to 13. Data included age, pT, pN, M stage, tumour size, vascular invasion and extra-thyroidal extension. From a cohort of 281 patients, 22 (8%) could now be considered for lobectomy alone. Of these, 4 had disease in the contralateral lobe (18%), all of which were low-risk tumours with no influence on recommendation for radioactive remnant ablation (RRA). Analysis of all patients, regardless of age, with pT1-2N0M0 disease (n = 50) revealed 11 (22%) had contralateral disease. The presence of index multifocal disease was predictive of disease in the contralateral lobe. One patient (2%) had a finding in the contralateral lobe which may potentially influence the recommendation for RRA. In no cases did findings in the contralateral lobe elevate a patient to a group where RRA was routinely recommended by BTA guidelines. The updated BTA guidelines are likely to affect only 8% of our cohort. Further analysis questions the role of age in excluding patients from a conservative approach. Copyright © 2018 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

Digital representation of oil and natural gas well pad scars in southwest Wyoming: 2012 update

USGS Publications Warehouse

Garman, Steven L.; McBeth, Jamie L.

2015-01-01

The recent proliferation of oil and natural gas energy development in the Greater Green River Basin of southwest Wyoming has accentuated the need to understand wildlife responses to this development. The location and extent of surface disturbance that is created by oil and natural gas well pad scars are key pieces of information used to assess the effects of energy infrastructure on wildlife populations and habitat. A digital database of oil and natural gas pad scars had previously been generated from 1-meter (m) National Agriculture Imagery Program imagery (NAIP) acquired in 2009 for a 7.7-million hectare (ha) (19,026,700 acres) region of southwest Wyoming. Scars included the pad area where wellheads, pumps, and storage facilities reside and the surrounding area that was scraped and denuded of vegetation during the establishment of the pad. Scars containing tanks, compressors, the storage of oil and gas related equipment, and produced-water ponds were also collected on occasion. This report updates the digital database for the five counties of southwest Wyoming (Carbon, Lincoln, Sublette, Sweetwater, Uinta) within the Wyoming Landscape Conservation Initiative (WLCI) study area and for a limited portion of Fremont, Natrona, and Albany Counties using 2012 1-m NAIP imagery and 2012 oil and natural gas well permit information. This report adds pad scars created since 2009, and updates attributes of all pad scars using the 2012 well permit information. These attributes include the origination year of the pad scar, the number of active and inactive wells on or near each pad scar in 2012, and the overall status of the pad scar (active or inactive). The new 2012 database contains 17,404 pad scars of which 15,532 are attributed as oil and natural gas well pads. Digital data are stored as shapefiles projected to the Universal Transverse Mercator (zones 12 and 13) coordinate system. These data are available from the U.S. Geological Survey (USGS) at http://dx.doi.org/10.3133/ds934.

Reducing Contingency through Sampling at the Luckey FUSRAP Site - 13186

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frothingham, David; Barker, Michelle; Buechi, Steve

2013-07-01

Typically, the greatest risk in developing accurate cost estimates for the remediation of hazardous, toxic, and radioactive waste sites is the uncertainty in the estimated volume of contaminated media requiring remediation. Efforts to address this risk in the remediation cost estimate can result in large cost contingencies that are often considered unacceptable when budgeting for site cleanups. Such was the case for the Luckey Formerly Utilized Sites Remedial Action Program (FUSRAP) site near Luckey, Ohio, which had significant uncertainty surrounding the estimated volume of site soils contaminated with radium, uranium, thorium, beryllium, and lead. Funding provided by the American Recoverymore » and Reinvestment Act (ARRA) allowed the U.S. Army Corps of Engineers (USACE) to conduct additional environmental sampling and analysis at the Luckey Site between November 2009 and April 2010, with the objective to further delineate the horizontal and vertical extent of contaminated soils in order to reduce the uncertainty in the soil volume estimate. Investigative work included radiological, geophysical, and topographic field surveys, subsurface borings, and soil sampling. Results from the investigative sampling were used in conjunction with Argonne National Laboratory's Bayesian Approaches for Adaptive Spatial Sampling (BAASS) software to update the contaminated soil volume estimate for the site. This updated volume estimate was then used to update the project cost-to-complete estimate using the USACE Cost and Schedule Risk Analysis process, which develops cost contingencies based on project risks. An investment of $1.1 M of ARRA funds for additional investigative work resulted in a reduction of 135,000 in-situ cubic meters (177,000 in-situ cubic yards) in the estimated base volume estimate. This refinement of the estimated soil volume resulted in a $64.3 M reduction in the estimated project cost-to-complete, through a reduction in the uncertainty in the contaminated soil volume estimate and the associated contingency costs. (authors)« less

MedlinePlus FAQ: How Often MedlinePlus is Updated

MedlinePlus

... System Pharmacists is updated monthly. Natural Medicines Comprehensive Database Consumer Version is updated quarterly. Medical Encyclopedia: Updated monthly. ... Guidelines Viewers & Players MedlinePlus Connect for ...

An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE)

PubMed Central

Althof, Stanley E; McMahon, Chris G; Waldinger, Marcel D; Serefoglu, Ege Can; Shindel, Alan W; Adaikan, P Ganesan; Becher, Edgardo; Dean, John; Giuliano, Francois; Hellstrom, Wayne JG; Giraldi, Annamaria; Glina, Sidney; Incrocci, Luca; Jannini, Emmanuele; McCabe, Marita; Parish, Sharon; Rowland, David; Segraves, R Taylor; Sharlip, Ira; Torres, Luiz Otavio

2014-01-01

Introduction In 2009, the International Society for Sexual Medicine (ISSM) convened a select panel of experts to develop an evidence-based set of guidelines for patients suffering from lifelong premature ejaculation (PE). That document reviewed definitions, etiology, impact on the patient and partner, assessment, and pharmacological, psychological, and combined treatments. It concluded by recognizing the continually evolving nature of clinical research and recommended a subsequent guideline review and revision every fourth year. Consistent with that recommendation, the ISSM organized a second multidisciplinary panel of experts in April 2013, which met for 2 days in Bangalore, India. This manuscript updates the previous guidelines and reports on the recommendations of the panel of experts. Aim The aim of this study was to develop clearly worded, practical, evidenced-based recommendations for the diagnosis and treatment of PE for family practice clinicians as well as sexual medicine experts. Method A comprehensive literature review was performed. Results This article contains the report of the second ISSM PE Guidelines Committee. It offers a new unified definition of PE and updates the previous treatment recommendations. Brief assessment procedures are delineated, and validated diagnostic and treatment questionnaires are reviewed. Finally, the best practices treatment recommendations are presented to guide clinicians, both familiar and unfamiliar with PE, in facilitating treatment of their patients. Conclusion Development of guidelines is an evolutionary process that continually reviews data and incorporates the best new research. We expect that ongoing research will lead to a more complete understanding of the pathophysiology as well as new efficacious and safe treatments for this sexual dysfunction. We again recommend that these guidelines be reevaluated and updated by the ISSM in 4 years. Althof SE, McMahon CG, Waldinger MD, Serefoglu EC, Shindel AW, Adaikan PG, Becher E, Dean J, Giuliano F, Hellstrom WJG, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, and Torres LO. An update of the International Society of Sexual Medicine's guidelines for the diagnosis and treatment of premature ejaculation (PE). Sex Med 2014;2:60–90. PMID:25356302

10 CFR 72.248 - Safety analysis report updating.

Code of Federal Regulations, 2014 CFR

2014-01-01

... appropriate, the last update to the FSAR under this section. The update shall include the effects 1 of: 1... for a spent fuel storage cask design shall update periodically, as provided in paragraph (b) of this... the issued Certificate of Compliance (CoC). (b) Each update shall contain all the changes necessary to...

10 CFR 72.248 - Safety analysis report updating.

Code of Federal Regulations, 2013 CFR

2013-01-01

... appropriate, the last update to the FSAR under this section. The update shall include the effects 1 of: 1... for a spent fuel storage cask design shall update periodically, as provided in paragraph (b) of this... the issued Certificate of Compliance (CoC). (b) Each update shall contain all the changes necessary to...

10 CFR 72.248 - Safety analysis report updating.

Code of Federal Regulations, 2012 CFR

2012-01-01

... appropriate, the last update to the FSAR under this section. The update shall include the effects 1 of: 1... for a spent fuel storage cask design shall update periodically, as provided in paragraph (b) of this... the issued Certificate of Compliance (CoC). (b) Each update shall contain all the changes necessary to...

10 CFR 72.248 - Safety analysis report updating.

Code of Federal Regulations, 2011 CFR

2011-01-01

... appropriate, the last update to the FSAR under this section. The update shall include the effects 1 of: 1... for a spent fuel storage cask design shall update periodically, as provided in paragraph (b) of this... the issued Certificate of Compliance (CoC). (b) Each update shall contain all the changes necessary to...