Modeled and Observed Altitude Distributions of the Micrometeoroid Influx in Radar Detection

NASA Astrophysics Data System (ADS)

Swarnalingam, N.; Janches, D.; Plane, J. M. C.; Carrillo-Sánchez, J. D.; Sternovsky, Z.; Pokorny, P.; Nesvorny, D.

2017-12-01

The altitude distributions of the micrometeoroids are a representation of the radar response function of the incoming flux and thus can be utilized to calibrate radar measurements. These in turn, can be used to determine the rate of ablation and ionization of the meteoroids and ultimately the input flux. During the ablation process, electrons are created and subsequently these electrons produce backscatter signals when they encounter the transmitted signals from radar. In this work, we investigate the altitude distribution by exploring different sizes as well as the aspect sensitivity of the meteor head echoes. We apply an updated version of the Chemical Ablation Model (CABMOD), which includes results from laboratory simulation of meteor ablation for different metallic constituents. In particular, the updated version simulates the ablation of Na. It is observed in the updated version that electrons are produced to a wider altitude range with the peak production occurs at lower altitudes compared to the previous version. The results are compared to head echo meteor observations utilizing the Arecibo 430 MHz radar.

Teaching Adaptability of Object-Oriented Programming Language Curriculum

ERIC Educational Resources Information Center

Zhu, Xiao-dong

2012-01-01

The evolution of object-oriented programming languages includes update of their own versions, update of development environments, and reform of new languages upon old languages. In this paper, the evolution analysis of object-oriented programming languages is presented in term of the characters and development. The notion of adaptive teaching upon…

TRMM Microwave Imager (TMI) Updates for Final Data Version Release

NASA Technical Reports Server (NTRS)

Kroodsma, Rachael A; Bilanow, Stephen; Ji, Yimin; McKague, Darren

2017-01-01

The Tropical Rainfall Measuring Mission (TRMM) Microwave Imager (TMI) dataset released by the Precipitation Processing System (PPS) will be updated to a final version within the next year. These updates are based on increased knowledge in recent years of radiometer calibration and sensor performance issues. In particular, the Global Precipitation Measurement (GPM) Microwave Imager (GMI) is used as a model for many of the TMI version updates. This paper discusses four aspects of the TMI data product that will be improved: spacecraft attitude, calibration and quality control, along-scan bias corrections, and sensor pointing accuracy. These updates will be incorporated into the final TMI data version, improving the quality of the data product and ensuring accurate geophysical parameters can be derived from TMI.

Chemical transport model simulations of organic aerosol in ...

EPA Pesticide Factsheets

Gasoline- and diesel-fueled engines are ubiquitous sources of air pollution in urban environments. They emit both primary particulate matter and precursor gases that react to form secondary particulate matter in the atmosphere. In this work, we updated the organic aerosol module and organic emissions inventory of a three-dimensional chemical transport model, the Community Multiscale Air Quality Model (CMAQ), using recent, experimentally derived inputs and parameterizations for mobile sources. The updated model included a revised volatile organic compound (VOC) speciation for mobile sources and secondary organic aerosol (SOA) formation from unspeciated intermediate volatility organic compounds (IVOCs). The updated model was used to simulate air quality in southern California during May and June 2010, when the California Research at the Nexus of Air Quality and Climate Change (CalNex) study was conducted. Compared to the Traditional version of CMAQ, which is commonly used for regulatory applications, the updated model did not significantly alter the predicted organic aerosol (OA) mass concentrations but did substantially improve predictions of OA sources and composition (e.g., POA–SOA split), as well as ambient IVOC concentrations. The updated model, despite substantial differences in emissions and chemistry, performed similar to a recently released research version of CMAQ (Woody et al., 2016) that did not include the updated VOC and IVOC emissions and SOA data

Author Correction: Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions.

PubMed

Nardi-Schreiber, Atara; Gamliel, Ayelet; Harris, Talia; Sapir, Gal; Sosna, Jacob; Gomori, J Moshe; Katz-Brull, Rachel

2018-05-22

The original version of the Supplementary Information associated with this Article contained an error in Supplementary Figure 2 and Supplementary Figure 5 in which the 31 P NMR spectral lines were missing. The HTML has been updated to include a corrected version of the Supplementary Information.

Robo-Sensei's NLP-Based Error Detection and Feedback Generation

ERIC Educational Resources Information Center

Nagata, Noriko

2009-01-01

This paper presents a new version of Robo-Sensei's NLP (Natural Language Processing) system which updates the version currently available as the software package "ROBO-SENSEI: Personal Japanese Tutor" (Nagata, 2004). Robo-Sensei's NLP system includes a lexicon, a morphological generator, a word segmentor, a morphological parser, a syntactic…

Updates to the Demographic and Spatial Allocation Models to ...

EPA Pesticide Factsheets

EPA announced the availability of the draft report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) for a 30-day public comment period. The ICLUS version 2 (v2) modeling tool furthered land change modeling by providing nationwide housing development scenarios up to 2100. ICLUS V2 includes updated population and land use data sets and addressing limitations identified in ICLUS v1 in both the migration and spatial allocation models. The companion user guide describes the development of ICLUS v2 and the updates that were made to the original data sets and the demographic and spatial allocation models. [2017 UPDATE] Get the latest version of ICLUS and stay up-to-date by signing up to the ICLUS mailing list. The GIS tool enables users to run SERGoM with the population projections developed for the ICLUS project and allows users to modify the spatial allocation housing density across the landscape.

Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN.

PubMed

Wahlgren, Nils; Moreira, Tiago; Michel, Patrik; Steiner, Thorsten; Jansen, Olav; Cognard, Christophe; Mattle, Heinrich P; van Zwam, Wim; Holmin, Staffan; Tatlisumak, Turgut; Petersson, Jesper; Caso, Valeria; Hacke, Werner; Mazighi, Mikael; Arnold, Marcel; Fischer, Urs; Szikora, Istvan; Pierot, Laurent; Fiehler, Jens; Gralla, Jan; Fazekas, Franz; Lees, Kennedy R

2016-01-01

The original version of this consensus statement on mechanical thrombectomy was approved at the European Stroke Organisation (ESO)-Karolinska Stroke Update conference in Stockholm, 16-18 November 2014. The statement has later, during 2015, been updated with new clinical trials data in accordance with a decision made at the conference. Revisions have been made at a face-to-face meeting during the ESO Winter School in Berne in February, through email exchanges and the final version has then been approved by each society. The recommendations are identical to the original version with evidence level upgraded by 20 February 2015 and confirmed by 15 May 2015. The purpose of the ESO-Karolinska Stroke Update meetings is to provide updates on recent stroke therapy research and to discuss how the results may be implemented into clinical routine. Selected topics are discussed at consensus sessions, for which a consensus statement is prepared and discussed by the participants at the meeting. The statements are advisory to the ESO guidelines committee. This consensus statement includes recommendations on mechanical thrombectomy after acute stroke. The statement is supported by ESO, European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), and European Academy of Neurology (EAN). © 2016 World Stroke Organization.

Summary of Expansions, Updates, and Results in GREET 2017 Suite of Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Michael; Elgowainy, Amgad; Han, Jeongwoo

This report provides a technical summary of the expansions and updates to the 2017 release of Argonne National Laboratory’s Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET®) model, including references and links to key technical documents related to these expansions and updates. The GREET 2017 release includes an updated version of the GREET1 (the fuel-cycle GREET model) and GREET2 (the vehicle-cycle GREET model), both in the Microsoft Excel platform and in the GREET.net modeling platform. Figure 1 shows the structure of the GREET Excel modeling platform. The .net platform integrates all GREET modules together seamlessly.

SU-E-J-101: Retroactive Calculation of TLD and Film Dose in Anthropomorphic Phantom as Assessment of Updated TPS Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alkhatib, H; Oves, S

Purpose: To demonstrate a quick and comprehensive method verifying the accuracy of the updated dose model by recalculating dose distribution in an anthropomorphic phantom with a new version of the TPS and comparing the results to measured values. Methods: CT images and IMRT plan of an RPC anthropomorphic head phantom, previously calculated by Pinnacle 9.0, was re-computed using Pinnacle 9.2 and 9.6. The dosimeters within the phantom include four TLD capsules representing a primary PTV, two TLD capsules representing a secondary PTV, and two TLD capsules representing an organ at risk. Also included were three sheets of Gafchromic film. Performancemore » of the updated TPS version was assessed by recalculating point doses and dose profiles corresponding to TLD and film position respectively and then comparing the results to reported values by the RPC. Results: Comparing calculated doses to reported measured doses from the RPC yielded an average disagreement of 1.48%, 2.04% and 2.10% for versions 9.0, 9.2, 9.6 respectively. Computed doses points all meet the RPC's passing criteria with the exception of the point representing the superior organ at risk in version 9.6. However, qualitative analysis of the recalculated dose profiles showed improved agreement with those of the RPC, especially in the penumbra region. Conclusion: This work has demonstrated the calculation results of Pinnacle 9.2 and 9.6 vs 9.0 version. Additionally, this study illustrates a method for the user to gain confidence upgrade to a newer version of the treatment planning system.« less

NCCN Guidelines Insights: Multiple Myeloma, Version 3.2018.

PubMed

Kumar, Shaji K; Callander, Natalie S; Alsina, Melissa; Atanackovic, Djordje; Biermann, J Sybil; Castillo, Jorge; Chandler, Jason C; Costello, Caitlin; Faiman, Matthew; Fung, Henry C; Godby, Kelly; Hofmeister, Craig; Holmberg, Leona; Holstein, Sarah; Huff, Carol Ann; Kang, Yubin; Kassim, Adetola; Liedtke, Michaela; Malek, Ehsan; Martin, Thomas; Neppalli, Vishala T; Omel, James; Raje, Noopur; Singhal, Seema; Somlo, George; Stockerl-Goldstein, Keith; Weber, Donna; Yahalom, Joachim; Kumar, Rashmi; Shead, Dorothy A

2018-01-01

The NCCN Guidelines for Multiple Myeloma provide recommendations for diagnosis, evaluation, treatment, including supportive-care, and follow-up for patients with myeloma. These NCCN Guidelines Insights highlight the important updates/changes specific to the myeloma therapy options in the 2018 version of the NCCN Guidelines. Copyright © 2018 by the National Comprehensive Cancer Network.

JPSS-1 VIIRS Version 2 At-Launch Relative Spectral Response Characterization and Performance

NASA Technical Reports Server (NTRS)

Moeller, Chris; Schwarting, Thomas; McIntire, Jeff; Moyer, Dave; Zeng, Jinan

2017-01-01

The relative spectral response (RSR) characterization of the JPSS-1 VIIRS spectral bands has achieved at launch status in the VIIRS Data Analysis Working Group February 2016 Version 2 RSR release. The Version 2 release improves upon the June 2015 Version 1 release by including December 2014 NIST TSIRCUS spectral measurements of VIIRS VisNIR bands in the analysis plus correcting CO2 influence on the band M13 RSR. The T-SIRCUS based characterization is merged with the summer 2014 SpMA based characterization of VisNIR bands (Version 1 release) to yield a fused RSR for these bands, combining the strengths of the T-SIRCUS and the SpMA measurement systems. The M13 RSR is updated by applying a model-based correction to mitigate CO2 attenuation of the SpMA source signal that occurred during M13 spectral measurements. The Version 2 release carries forward the Version 1 RSR for those bands that were not updated (M8-M12, M14-M16AB, I3-I5, DNBMGS). The Version 2 release includes band average (overall detectors and subsamples) RSR plus supporting RSR for each detector and subsample. The at-launch band average RSR have been used to populate Look-Up Tables supporting the sensor data record and environmental data record at-launch science products. Spectral performance metrics show that JPSS-1VIIRS RSR are compliant on specifications with a few minor exceptions. The Version 2 release, which replaces the Version 1 release, is currently available on the password-protected NASA JPSS-1 eRooms under EAR99 control.

Energy 101: Wind Turbines - 2014 Update

ScienceCinema

None

2018-05-11

See how wind turbines generate clean electricity from the power of wind. The video highlights the basic principles at work in wind turbines, and illustrates how the various components work to capture and convert wind energy to electricity. This updated version also includes information on the Energy Department's efforts to advance offshore wind power. Offshore wind energy footage courtesy of Vestas.

UPEML Version 3.0: A machine-portable CDC update emulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mehlhorn, T.A.; Haill, T.A.

1992-04-01

UPEML is a machine-portable program that emulates a subset of the functions of the standard CDC Update. Machine-portability has been achieved by conforming to ANSI standards for Fortran-77. UPEML is compact and fairly efficient; however, it only allows a restricted syntax as compared with the CDC Update. This program was written primarily to facilitate the use of CDC-based scientific packages on alternate computer systems such as the VAX/VMS mainframes and UNIX workstations. UPEML has also been successfully used on the multiprocessor ELXSI, on CRAYs under both UNICOS and CTSS operating systems, and on Sun, HP, Stardent and IBM workstations. UPEMLmore » was originally released with the ITS electron/photon Monte Carlo transport package, which was developed on a CDC-7600 and makes extensive use of conditional file structure to combine several problem geometry and machine options into a single program file. UPEML 3.0 is an enhanced version of the original code and is being independently released for use at any installation or with any code package. Version 3.0 includes enhanced error checking, full ASCII character support, a program library audit capability, and a partial update option in which only selected or modified decks are written to the complete file. Version 3.0 also checks for overlapping corrections, allows processing of pested calls to common decks, and allows the use of alternate files in READ and ADDFILE commands. Finally, UPEML Version 3.0 allows the assignment of input and output files at runtime on the control line.« less

UPEML Version 3. 0: A machine-portable CDC update emulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mehlhorn, T.A.; Haill, T.A.

1992-04-01

UPEML is a machine-portable program that emulates a subset of the functions of the standard CDC Update. Machine-portability has been achieved by conforming to ANSI standards for Fortran-77. UPEML is compact and fairly efficient; however, it only allows a restricted syntax as compared with the CDC Update. This program was written primarily to facilitate the use of CDC-based scientific packages on alternate computer systems such as the VAX/VMS mainframes and UNIX workstations. UPEML has also been successfully used on the multiprocessor ELXSI, on CRAYs under both UNICOS and CTSS operating systems, and on Sun, HP, Stardent and IBM workstations. UPEMLmore » was originally released with the ITS electron/photon Monte Carlo transport package, which was developed on a CDC-7600 and makes extensive use of conditional file structure to combine several problem geometry and machine options into a single program file. UPEML 3.0 is an enhanced version of the original code and is being independently released for use at any installation or with any code package. Version 3.0 includes enhanced error checking, full ASCII character support, a program library audit capability, and a partial update option in which only selected or modified decks are written to the complete file. Version 3.0 also checks for overlapping corrections, allows processing of pested calls to common decks, and allows the use of alternate files in READ and ADDFILE commands. Finally, UPEML Version 3.0 allows the assignment of input and output files at runtime on the control line.« less

Standard interface files and procedures for reactor physics codes, version III

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carmichael, B.M.

Standards and procedures for promoting the exchange of reactor physics codes are updated to Version-III status. Standards covering program structure, interface files, file handling subroutines, and card input format are included. The implementation status of the standards in codes and the extension of the standards to new code areas are summarized. (15 references) (auth)

Author Correction: Atomic-resolution three-dimensional hydration structures on a heterogeneously charged surface.

PubMed

Umeda, Kenichi; Zivanovic, Lidija; Kobayashi, Kei; Ritala, Juha; Kominami, Hiroaki; Spijker, Peter; Foster, Adam S; Yamada, Hirofumi

2018-05-23

The original version of the Supplementary Information associated with this Article contained an error in Supplementary Figure 9e,f in which the y-axes were incorrectly labelled from '-40' to '40', rather than the correct '-400' to '400'. The HTML has been updated to include a corrected version of the Supplementary Information.

Completion of the 2006 National Land Cover Database Update for the Conterminous United States

EPA Science Inventory

Under the organization of the Multi-Resolution Land Characteristics (MRLC) Consortium, the National Land Cover Database (NLCD) has been updated to characterize both land cover and land cover change from 2001 to 2006. An updated version of NLCD 2001 (Version 2.0) is also provided....

CHOgenome.org 2.0: Genome resources and website updates.

PubMed

Kremkow, Benjamin G; Baik, Jong Youn; MacDonald, Madolyn L; Lee, Kelvin H

2015-07-01

Chinese hamster ovary (CHO) cells are a major host cell line for the production of therapeutic proteins, and CHO cell and Chinese hamster (CH) genomes have recently been sequenced using next-generation sequencing methods. CHOgenome.org was launched in 2011 (version 1.0) to serve as a database repository and to provide bioinformatics tools for the CHO community. CHOgenome.org (version 1.0) maintained GenBank CHO-K1 genome data, identified CHO-omics literature, and provided a CHO-specific BLAST service. Recent major updates to CHOgenome.org (version 2.0) include new sequence and annotation databases for both CHO and CH genomes, a more user-friendly website, and new research tools, including a proteome browser and a genome viewer. CHO cell-line specific sequences and annotations facilitate cell line development opportunities, several of which are discussed. Moving forward, CHOgenome.org will host the increasing amount of CHO-omics data and continue to make useful bioinformatics tools available to the CHO community. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

NCCN Guidelines Insights: Breast Cancer, Version 1.2017.

PubMed

Gradishar, William J; Anderson, Benjamin O; Balassanian, Ron; Blair, Sarah L; Burstein, Harold J; Cyr, Amy; Elias, Anthony D; Farrar, William B; Forero, Andres; Giordano, Sharon Hermes; Goetz, Matthew P; Goldstein, Lori J; Isakoff, Steven J; Lyons, Janice; Marcom, P Kelly; Mayer, Ingrid A; McCormick, Beryl; Moran, Meena S; O'Regan, Ruth M; Patel, Sameer A; Pierce, Lori J; Reed, Elizabeth C; Salerno, Kilian E; Schwartzberg, Lee S; Sitapati, Amy; Smith, Karen Lisa; Smith, Mary Lou; Soliman, Hatem; Somlo, George; Telli, Melinda; Ward, John H; Shead, Dorothy A; Kumar, Rashmi

2017-04-01

These NCCN Guidelines Insights highlight the important updates/changes to the surgical axillary staging, radiation therapy, and systemic therapy recommendations for hormone receptor-positive disease in the 1.2017 version of the NCCN Guidelines for Breast Cancer. This report summarizes these updates and discusses the rationale behind them. Updates on new drug approvals, not available at press time, can be found in the most recent version of these guidelines at NCCN.org. Copyright © 2017 by the National Comprehensive Cancer Network.

Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Final Report, Version 2)

EPA Science Inventory

EPA's announced the availability of the final report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Version 2). This update furthered land change modeling by providing nationwide housing developmen...

JPSS-1 VIIRS version 2 at-launch relative spectral response characterization and performance

NASA Astrophysics Data System (ADS)

Moeller, Chris; Schwarting, Tom; McIntire, Jeff; Moyer, David I.; Zeng, Jinan

2016-09-01

The relative spectral response (RSR) characterization of the JPSS-1 VIIRS spectral bands has achieved "at launch" status in the VIIRS Data Analysis Working Group February 2016 Version 2 RSR release. The Version 2 release improves upon the June 2015 Version 1 release by including December 2014 NIST TSIRCUS spectral measurements of VIIRS VisNIR bands in the analysis plus correcting CO2 influence on the band M13 RSR. The T-SIRCUS based characterization is merged with the summer 2014 SpMA based characterization of VisNIR bands (Version 1 release) to yield a "fused" RSR for these bands, combining the strengths of the T-SIRCUS and the SpMA measurement systems. The M13 RSR is updated by applying a model-based correction to mitigate CO2 attenuation of the SpMA source signal that occurred during M13 spectral measurements. The Version 2 release carries forward the Version 1 RSR for those bands that were not updated (M8-M12, M14-M16A/B, I3-I5, DNBMGS). The Version 2 release includes band average (over all detectors and subsamples) RSR plus supporting RSR for each detector and subsample. The at-launch band average RSR have been used to populate Look-Up Tables supporting the sensor data record and environmental data record at-launch science products. Spectral performance metrics show that JPSS-1 VIIRS RSR are compliant on specifications with a few minor exceptions. The Version 2 release, which replaces the Version 1 release, is currently available on the password-protected NASA JPSS-1 eRooms under EAR99 control.

Applying Modern Marketing Concepts to Military Recruiting

DTIC Science & Technology

2000-03-03

new to military recruiting or are an updated version of currently used concepts. The concepts and systems include social marketing, marketing ... research , market planning and product development, pricing and management. New simulated application including a strategic planning war game and a simulated

New Open-Source Version of FLORIS Released | News | NREL

Science.gov Websites

New Open-Source Version of FLORIS Released New Open-Source Version of FLORIS Released January 26 , 2018 National Renewable Energy Laboratory (NREL) researchers recently released an updated open-source simplified and documented. Because of the living, open-source nature of the newly updated utility, NREL

Key science issues in the central and eastern United States for the next version of the USGS National Seismic Hazard Maps

USGS Publications Warehouse

Peterson, M.D.; Mueller, C.S.

2011-01-01

The USGS National Seismic Hazard Maps are updated about every six years by incorporating newly vetted science on earthquakes and ground motions. The 2008 hazard maps for the central and eastern United States region (CEUS) were updated by using revised New Madrid and Charleston source models, an updated seismicity catalog and an estimate of magnitude uncertainties, a distribution of maximum magnitudes, and several new ground-motion prediction equations. The new models resulted in significant ground-motion changes at 5 Hz and 1 Hz spectral acceleration with 5% damping compared to the 2002 version of the hazard maps. The 2008 maps have now been incorporated into the 2009 NEHRP Recommended Provisions, the 2010 ASCE-7 Standard, and the 2012 International Building Code. The USGS is now planning the next update of the seismic hazard maps, which will be provided to the code committees in December 2013. Science issues that will be considered for introduction into the CEUS maps include: 1) updated recurrence models for New Madrid sources, including new geodetic models and magnitude estimates; 2) new earthquake sources and techniques considered in the 2010 model developed by the nuclear industry; 3) new NGA-East ground-motion models (currently under development); and 4) updated earthquake catalogs. We will hold a regional workshop in late 2011 or early 2012 to discuss these and other issues that will affect the seismic hazard evaluation in the CEUS.

S3 Guideline for the treatment of psoriasis vulgaris, update - Short version part 1 - Systemic treatment.

PubMed

Nast, Alexander; Amelunxen, Lasse; Augustin, Matthias; Boehncke, Wolf-Henning; Dressler, Corinna; Gaskins, Matthew; Härle, Peter; Hoffstadt, Bernd; Klaus, Joachim; Koza, Joachim; Mrowietz, Ulrich; Ockenfels, Hans-Michael; Philipp, Sandra; Reich, Kristian; Rosenbach, Thomas; Rzany, Berthold; Schlaeger, Martin; Schmid-Ott, Gerhard; Sebastian, Michael; von Kiedrowski, Ralph; Weberschock, Tobias

2018-05-01

The German guideline for the treatment of psoriasis vulgaris was updated using GRADE methodology. The guideline is based on a systematic literature review completed on December 1, 2016, and on a formal consensus and approval process. The first section of this short version of the guideline covers systemic treatment options considered relevant by the expert panel and approved in Germany at the time of the consensus conference (acitretin, adalimumab, apremilast, cyclosporine, etanercept, fumaric acid esters, infliximab, methotrexate, secukinumab and ustekinumab). Detailed information is provided on the management and monitoring of the included treatment options. © 2018 The Authors | Journal compilation © Blackwell Verlag GmbH, Berlin.

Summary: Update to ASTM Guide E 1523 to Charge Control and Charge Referencing Techniques in X-ray Photoelectron Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baer, Donald R.

2005-04-22

An updated version of the ASTM guide E1523 to the methods to charge control and charge referencing techniques in x-ray photoelectron spectroscopy has been released by ASTM. The guide is meant to acquaint x-ray photoelectron spectroscopy (XPS) users with the various charge control and charge referencing techniques that are and have been used in the acquisition and interpretation of XPS data from surfaces of insulating specimens. The current guide has been expanded to include new references as well as recommendations for reporting information on charge control and charge referencing. The previous version of the document had been published in 1997.

Rare Earth Geochemistry of Rock Core form WY Reservoirs

DOE Data Explorer

Quillinan, Scott; Bagdonnas, Davin; McLaughlin, J. Fred; Nye, Charles

2016-10-01

These data include major, minor, trace and rare earth element concentration of geologic formations in Wyoming oil and gas fields. *Note - Link below contains updated version of spreadsheet (6/14/2017)

SPECIATE Version 4.5 Database Development Documentation

EPA Science Inventory

This product updated SPECIATE 4.4 with new emission profiles to address high priority Agency data gaps and to included new, more accurate emission profiles generated by research underway within and outside the Agency.

Comparisons of ANS, ASME, AWS, and NFPA standards cited in the NRC standard review plan, NUREG-0800, and related documents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ankrum, A.R.; Bohlander, K.L.; Gilbert, E.R.

This report provides the results of comparisons of the cited and latest versions of ANS, ASME, AWS and NFPA standards cited in the NRC Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants (NUREG 0800) and related documents. The comparisons were performed by Battelle Pacific Northwest Laboratories in support of the NRC`s Standard Review Plan Update and Development Program. Significant changes to the standards, from the cited version to the latest version, are described and discussed in a tabular format for each standard. Recommendations for updating each citation in the Standard Review Plan are presented.more » Technical considerations and suggested changes are included for related regulatory documents (i.e., Regulatory Guides and the Code of Federal Regulations) citing the standard. The results and recommendations presented in this document have not been subjected to NRC staff review.« less

Ladtap XL Version 2017: A Spreadsheet For Estimating Dose Resulting From Aqueous Releases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minter, K.; Jannik, T.

LADTAP XL© is an EXCEL© spreadsheet used to estimate dose to offsite individuals and populations resulting from routine and accidental releases of radioactive materials to the Savannah River. LADTAP XL© contains two worksheets: LADTAP and IRRIDOSE. The LADTAP worksheet estimates dose for environmental pathways including external exposure resulting from recreational activities on the Savannah River and internal exposure resulting from ingestion of water, fish, and invertebrates originating from the Savannah River. IRRIDOSE estimates offsite dose to individuals and populations from irrigation of foodstuffs with contaminated water from the Savannah River. In 2004, a complete description of the LADTAP XL© codemore » and an associated user’s manual was documented in LADTAP XL©: A Spreadsheet for Estimating Dose Resulting from Aqueous Release (WSRC-TR-2004-00059) and revised input parameters, dose coefficients, and radionuclide decay constants were incorporated into LADTAP XL© Version 2013 (SRNL-STI-2011-00238). LADTAP XL© Version 2017 is a slight modification to Version 2013 with minor changes made for more user-friendly parameter inputs and organization, updates in the time conversion factors used within the dose calculations, and fixed an issue with the expected time build-up parameter referenced within the population shoreline dose calculations. This manual has been produced to update the code description, verification of the models, and provide an updated user’s manual. LADTAP XL© Version 2017 has been verified by Minter (2017) and is ready for use at the Savannah River Site (SRS).« less

ASPEN Version 3.0

NASA Technical Reports Server (NTRS)

Rabideau, Gregg; Chien, Steve; Knight, Russell; Schaffer, Steven; Tran, Daniel; Cichy, Benjamin; Sherwood, Robert

2006-01-01

The Automated Scheduling and Planning Environment (ASPEN) computer program has been updated to version 3.0. ASPEN is a modular, reconfigurable, application software framework for solving batch problems that involve reasoning about time, activities, states, and resources. Applications of ASPEN can include planning spacecraft missions, scheduling of personnel, and managing supply chains, inventories, and production lines. ASPEN 3.0 can be customized for a wide range of applications and for a variety of computing environments that include various central processing units and random access memories.

Land Boundary Conditions for the Goddard Earth Observing System Model Version 5 (GEOS-5) Climate Modeling System: Recent Updates and Data File Descriptions

NASA Technical Reports Server (NTRS)

Mahanama, Sarith P.; Koster, Randal D.; Walker, Gregory K.; Takacs, Lawrence L.; Reichle, Rolf H.; De Lannoy, Gabrielle; Liu, Qing; Zhao, Bin; Suarez, Max J.

2015-01-01

The Earths land surface boundary conditions in the Goddard Earth Observing System version 5 (GEOS-5) modeling system were updated using recent high spatial and temporal resolution global data products. The updates include: (i) construction of a global 10-arcsec land-ocean lakes-ice mask; (ii) incorporation of a 10-arcsec Globcover 2009 land cover dataset; (iii) implementation of Level 12 Pfafstetter hydrologic catchments; (iv) use of hybridized SRTM global topography data; (v) construction of the HWSDv1.21-STATSGO2 merged global 30 arc second soil mineral and carbon data in conjunction with a highly-refined soil classification system; (vi) production of diffuse visible and near-infrared 8-day MODIS albedo climatologies at 30-arcsec from the period 2001-2011; and (vii) production of the GEOLAND2 and MODIS merged 8-day LAI climatology at 30-arcsec for GEOS-5. The global data sets were preprocessed and used to construct global raster data files for the software (mkCatchParam) that computes parameters on catchment-tiles for various atmospheric grids. The updates also include a few bug fixes in mkCatchParam, as well as changes (improvements in algorithms, etc.) to mkCatchParam that allow it to produce tile-space parameters efficiently for high resolution AGCM grids. The update process also includes the construction of data files describing the vegetation type fractions, soil background albedo, nitrogen deposition and mean annual 2m air temperature to be used with the future Catchment CN model and the global stream channel network to be used with the future global runoff routing model. This report provides detailed descriptions of the data production process and data file format of each updated data set.

NCCN Guidelines® Insights Bladder Cancer, Version 2.2016 Featured Updates to the NCCN Guidelines

PubMed Central

Clark, Peter E.; Spiess, Philippe E.; Agarwal, Neeraj; Bangs, Rick; Boorjian, Stephen A.; Buyyounouski, Mark K.; Efstathiou, Jason A.; Flaig, Thomas W.; Friedlander, Terence; Greenberg, Richard E.; Guru, Khurshid A.; Hahn, Noah; Herr, Harry W.; Hoimes, Christopher; Inman, Brant A.; Kader, A. Karim; Kibel, Adam S.; Kuzel, Timothy M.; Lele, Subodh M.; Meeks, Joshua J.; Michalski, Jeff; Montgomery, Jeffrey S.; Pagliaro, Lance C.; Pal, Sumanta K.; Patterson, Anthony; Petrylak, Daniel; Plimack, Elizabeth R.; Pohar, Kamal S.; Porter, Michael P.; Sexton, Wade J.; Siefker-Radtke, Arlene O.; Sonpavde, Guru; Tward, Jonathan; Wile, Geoffrey; Dwyer, Mary A.; Smith, Courtney

2017-01-01

These NCCN Guidelines Insights discuss the major recent updates to the NCCN Guidelines for Bladder Cancer based on the review of the evidence in conjunction with the expert opinion of the panel. Recent updates include (1) refining the recommendation of intravesical bacillus Calmette-Guérin, (2) strengthening the recommendations for perioperative systemic chemotherapy, and (3) incorporating immunotherapy into second-line therapy for locally advanced or metastatic disease. These NCCN Guidelines Insights further discuss factors that affect integration of these recommendations into clinical practice. PMID:27697976

Update on PISCES

NASA Technical Reports Server (NTRS)

Pearson, Don; Hamm, Dustin; Kubena, Brian; Weaver, Jonathan K.

2010-01-01

An updated version of the Platform Independent Software Components for the Exploration of Space (PISCES) software library is available. A previous version was reported in Library for Developing Spacecraft-Mission-Planning Software (MSC-22983), NASA Tech Briefs, Vol. 25, No. 7 (July 2001), page 52. To recapitulate: This software provides for Web-based, collaborative development of computer programs for planning trajectories and trajectory- related aspects of spacecraft-mission design. The library was built using state-of-the-art object-oriented concepts and software-development methodologies. The components of PISCES include Java-language application programs arranged in a hierarchy of classes that facilitates the reuse of the components. As its full name suggests, the PISCES library affords platform-independence: The Java language makes it possible to use the classes and application programs with a Java virtual machine, which is available in most Web-browser programs. Another advantage is expandability: Object orientation facilitates expansion of the library through creation of a new class. Improvements in the library since the previous version include development of orbital-maneuver- planning and rendezvous-launch-window application programs, enhancement of capabilities for propagation of orbits, and development of a desktop user interface.

MedlinePlus FAQ: How Often MedlinePlus is Updated

MedlinePlus

... System Pharmacists is updated monthly. Natural Medicines Comprehensive Database Consumer Version is updated quarterly. Medical Encyclopedia: Updated monthly. ... Guidelines Viewers & Players MedlinePlus Connect for ...

GAMBIT: the global and modular beyond-the-standard-model inference tool. Addendum for GAMBIT 1.1: Mathematica backends, SUSYHD interface and updated likelihoods

NASA Astrophysics Data System (ADS)

Athron, Peter; Balazs, Csaba; Bringmann, Torsten; Buckley, Andy; Chrząszcz, Marcin; Conrad, Jan; Cornell, Jonathan M.; Dal, Lars A.; Dickinson, Hugh; Edsjö, Joakim; Farmer, Ben; Gonzalo, Tomás E.; Jackson, Paul; Krislock, Abram; Kvellestad, Anders; Lundberg, Johan; McKay, James; Mahmoudi, Farvah; Martinez, Gregory D.; Putze, Antje; Raklev, Are; Ripken, Joachim; Rogan, Christopher; Saavedra, Aldo; Savage, Christopher; Scott, Pat; Seo, Seon-Hee; Serra, Nicola; Weniger, Christoph; White, Martin; Wild, Sebastian

2018-02-01

In Ref. (GAMBIT Collaboration: Athron et. al., Eur. Phys. J. C. arXiv:1705.07908, 2017) we introduced the global-fitting framework GAMBIT. In this addendum, we describe a new minor version increment of this package. GAMBIT 1.1 includes full support for Mathematica backends, which we describe in some detail here. As an example, we backend SUSYHD (Vega and Villadoro, JHEP 07:159, 2015), which calculates the mass of the Higgs boson in the MSSM from effective field theory. We also describe updated likelihoods in PrecisionBit and DarkBit, and updated decay data included in DecayBit.

Evaluating the Effectiveness of an Undergraduate Multicultural Course

ERIC Educational Resources Information Center

Chappell, Charisse

2014-01-01

The American Psychological Association (APA) recently revised their "Guidelines for the undergraduate psychology major" in 2013. In this updated version diversity is included in the broad goal of ethical and social responsibility in a diverse world. Indicators associated with this goal include student awareness of prejudice within…

Updating sea spray aerosol emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2

NASA Astrophysics Data System (ADS)

Gantt, B.; Kelly, J. T.; Bash, J. O.

2015-11-01

Sea spray aerosols (SSAs) impact the particle mass concentration and gas-particle partitioning in coastal environments, with implications for human and ecosystem health. Model evaluations of SSA emissions have mainly focused on the global scale, but regional-scale evaluations are also important due to the localized impact of SSAs on atmospheric chemistry near the coast. In this study, SSA emissions in the Community Multiscale Air Quality (CMAQ) model were updated to enhance the fine-mode size distribution, include sea surface temperature (SST) dependency, and reduce surf-enhanced emissions. Predictions from the updated CMAQ model and those of the previous release version, CMAQv5.0.2, were evaluated using several coastal and national observational data sets in the continental US. The updated emissions generally reduced model underestimates of sodium, chloride, and nitrate surface concentrations for coastal sites in the Bay Regional Atmospheric Chemistry Experiment (BRACE) near Tampa, Florida. Including SST dependency to the SSA emission parameterization led to increased sodium concentrations in the southeastern US and decreased concentrations along parts of the Pacific coast and northeastern US. The influence of sodium on the gas-particle partitioning of nitrate resulted in higher nitrate particle concentrations in many coastal urban areas due to increased condensation of nitric acid in the updated simulations, potentially affecting the predicted nitrogen deposition in sensitive ecosystems. Application of the updated SSA emissions to the California Research at the Nexus of Air Quality and Climate Change (CalNex) study period resulted in a modest improvement in the predicted surface concentration of sodium and nitrate at several central and southern California coastal sites. This update of SSA emissions enabled a more realistic simulation of the atmospheric chemistry in coastal environments where marine air mixes with urban pollution.

Modular reweighting software for statistical mechanical analysis of biased equilibrium data

NASA Astrophysics Data System (ADS)

Sindhikara, Daniel J.

2012-07-01

Here a simple, useful, modular approach and software suite designed for statistical reweighting and analysis of equilibrium ensembles is presented. Statistical reweighting is useful and sometimes necessary for analysis of equilibrium enhanced sampling methods, such as umbrella sampling or replica exchange, and also in experimental cases where biasing factors are explicitly known. Essentially, statistical reweighting allows extrapolation of data from one or more equilibrium ensembles to another. Here, the fundamental separable steps of statistical reweighting are broken up into modules - allowing for application to the general case and avoiding the black-box nature of some “all-inclusive” reweighting programs. Additionally, the programs included are, by-design, written with little dependencies. The compilers required are either pre-installed on most systems, or freely available for download with minimal trouble. Examples of the use of this suite applied to umbrella sampling and replica exchange molecular dynamics simulations will be shown along with advice on how to apply it in the general case. New version program summaryProgram title: Modular reweighting version 2 Catalogue identifier: AEJH_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEJH_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License, version 3 No. of lines in distributed program, including test data, etc.: 179 118 No. of bytes in distributed program, including test data, etc.: 8 518 178 Distribution format: tar.gz Programming language: C++, Python 2.6+, Perl 5+ Computer: Any Operating system: Any RAM: 50-500 MB Supplementary material: An updated version of the original manuscript (Comput. Phys. Commun. 182 (2011) 2227) is available Classification: 4.13 Catalogue identifier of previous version: AEJH_v1_0 Journal reference of previous version: Comput. Phys. Commun. 182 (2011) 2227 Does the new version supersede the previous version?: Yes Nature of problem: While equilibrium reweighting is ubiquitous, there are no public programs available to perform the reweighting in the general case. Further, specific programs often suffer from many library dependencies and numerical instability. Solution method: This package is written in a modular format that allows for easy applicability of reweighting in the general case. Modules are small, numerically stable, and require minimal libraries. Reasons for new version: Some minor bugs, some upgrades needed, error analysis added. analyzeweight.py/analyzeweight.py2 has been replaced by “multihist.py”. This new program performs all the functions of its predecessor while being versatile enough to handle other types of histograms and probability analysis. “bootstrap.py” was added. This script performs basic bootstrap resampling allowing for error analysis of data. “avg_dev_distribution.py” was added. This program computes the averages and standard deviations of multiple distributions, making error analysis (e.g. from bootstrap resampling) easier to visualize. WRE.cpp was slightly modified purely for cosmetic reasons. The manual was updated for clarity and to reflect version updates. Examples were removed from the manual in favor of online tutorials (packaged examples remain). Examples were updated to reflect the new format. An additional example is included to demonstrate error analysis. Running time: Preprocessing scripts 1-5 minutes, WHAM engine <1 minute, postprocess script ∼1-5 minutes.

The 2006 Cape Canaveral Air Force Station Range Reference Atmosphere Model Validation Study and Sensitivity Analysis to the National Aeronautics and Space Administration's Space Shuttle

NASA Technical Reports Server (NTRS)

Burns, Lee; Merry, Carl; Decker, Ryan; Harrington, Brian

2008-01-01

The 2006 Cape Canaveral Air Force Station (CCAFS) Range Reference Atmosphere (RRA) is a statistical model summarizing the wind and thermodynamic atmospheric variability from surface to 70 kin. Launches of the National Aeronautics and Space Administration's (NASA) Space Shuttle from Kennedy Space Center utilize CCAFS RRA data to evaluate environmental constraints on various aspects of the vehicle during ascent. An update to the CCAFS RRA was recently completed. As part of the update, a validation study on the 2006 version was conducted as well as a comparison analysis of the 2006 version to the existing CCAFS RRA database version 1983. Assessments to the Space Shuttle vehicle ascent profile characteristics were performed to determine impacts of the updated model to the vehicle performance. Details on the model updates and the vehicle sensitivity analyses with the update model are presented.

Major Upgrades to the AIRS Version-6 Water Vapor Profile Methodology

NASA Technical Reports Server (NTRS)

Susskind, Joel; Blaisdell, John; Iredell, Lena; Lee, Jae N.

2015-01-01

Additional changes in Version-6.19 include all previous updates made to the q(p) retrieval since Version-6: Modified Neural-Net q0(p) guess above the tropopause Linearly tapers the neural net guess to match climatology at 70 mb, not at the top of the atmosphereChanged the 11 trapezoid q(p) perturbation functions used in Version-6 so as to match the 24 functions used in T(p) retrieval step. These modifications resulted in improved water vapor profiles in Version-6.19 compared to Version-6.Version-6.19 is tested for all of August 2013 and August 2014, as well for select other days. Before finalized and operational in 2016, the V-6.19 can be acquired upon request for limited time intervals.

Getting to 2014 (and beyond): The Choices and Challenges Ahead. A Collection of Essays to Encourage Constructive Dialogue among Policymakers, Educators, and Practitioners Engaged in School Reform

ERIC Educational Resources Information Center

Balfanz, Robert; Boer, Benjamin; Carey, Kevin; Cohen, Michael; Hassel, Bryan C.; Hassel, Emily Ayscue; Hyslop, Anne; Levin, Douglas A.; Fletcher, Geoffrey; Odden, Allan; Tucker, Bill; Vargas, Joel

2012-01-01

Education Sector commissioned an earlier version of this collection of essays in conjunction with a March 2012 event "Getting to 2014: The Choices and Challenges Ahead." This updated version includes new essays and a revised introduction. The aim of these essays is to present ideas, elicit feedback, and encourage productive dialogue…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurtz, S.

This report summarizes the current status of the CPV industry and is updated from previous versions to include information from the last year. New information presented at the CPV-8 conference is included along with the addition of new companies that have announced their interest in CPV, and estimates of production volumes for 2011 and 2012.

AeroDyn V15.04: Design tool for wind and MHK turbines

DOE Data Explorer

Murray, Robynne; Hayman, Greg; Jonkman, Jason

2017-04-28

AeroDyn is a time-domain wind and MHK turbine aerodynamics module that can be coupled into the FAST version 8 multi-physics engineering tool to enable aero-elastic simulation of horizontal-axis wind turbines. AeroDyn V15.04 has been updated to include a cavitation check for MHK turbines, and can be driven as a standalone code to compute wind turbine aerodynamic response uncoupled from FAST. Note that while AeroDyn has been updated to v15.04, FAST v8.16 has not yet been updated and still uses AeroDyn v15.03.

A System for Supporting Development and Update of the International Classification of Health Interventions (ICHI).

PubMed

Donada, Marc; Della Mea, Vincenzo; Cumerlato, Megan; Rankin, Nicole; Madden, Richard

2018-01-01

The International Classification of Health Interventions (ICHI) is a member of the WHO Family of International Classifications, being developed to provide a common tool for reporting and analysing health interventions for statistical purposes. A web-based platform for classification development and update has been specifically developed to support the initial development step and then, after final approval, the continuous revision and update of the classification. The platform provides features for classification editing, versioning, comment management and URI identifiers. During the last 12 months it has been used for developing the ICHI Beta version, replacing the previous process based on the exchange of Excel files. At November 2017, 90 users have provided input to the development of the classification, which has resulted in 2913 comments and 2971 changes in the classification, since June 2017. Further work includes the development of an URI API for machine to machine communication, following the model established for ICD-11.

Updated fracture incidence rates for the US version of FRAX (registered trademark)

USDA-ARS?s Scientific Manuscript database

Evaluation of results produced by the US version of FRAX (trademarked) indicates that this tool overestimates the likelihood of major osteoporotic fracture. In an attempt to correct this, we updated underlying baseline fracture rates for the model. We used US hospital discharge data from 2006 to ca...

An Update on Modifications to Water Treatment Plant Model

EPA Science Inventory

Water treatment plant (WTP) model is an EPA tool for informing regulatory options. WTP has a few versions: 1). WTP2.2 can help in regulatory analysis. An updated version (WTP3.0) will allow plant-specific analysis (WTP-ccam) and thus help meet plant-specific treatment objectives...

IMS Version 3 Student Data Base Maintenance Program.

ERIC Educational Resources Information Center

Brown, John R.

Computer routines that update the Instructional Management System (IMS) Version 3 student data base which supports the Southwest Regional Laboratory's (SWRL) student monitoring system are described. Written in IBM System 360 FORTRAN IV, the program updates the data base by adding, changing and deleting records, as well as adding and deleting…

Incremental Testing of the Community Multiscale Air Quality (CMAQ) Modeling System Version 4.7

EPA Science Inventory

This paper describes the scientific and structural updates to the latest release of the Community Multiscale Air Quality (CMAQ) modeling system version 4.7 (v4.7) and points the reader to additional resources for further details. The model updates were evaluated relative to obse...

DSS command software update

NASA Technical Reports Server (NTRS)

Stinnett, W. G.

1980-01-01

The modifications, additions, and testing results for a version of the Deep Space Station command software, generated for support of the Voyager Saturn encounter, are discussed. The software update requirements included efforts to: (1) recode portions of the software to permit recovery of approximately 2000 words of memory; (2) correct five Voyager Ground data System liens; (3) provide capability to automatically turn off the command processor assembly local printer during periods of low activity; and (4) correct anomalies existing in the software.

NACS Store Planning Manual.

ERIC Educational Resources Information Center

College Store Journal, 1979

1979-01-01

Topics discussed by the NACS Store Planning/Renovation Committees in this updated version of the college store renovation manual include: short- and long-range planning, financial considerations, professional planning assistance, the store's image and business character, location considerations, building requirements, space requirements, fixtures,…

Motivation and Design of the Sirocco Storage System Version 1.0.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Curry, Matthew Leon; Ward, H. Lee; Danielson, Geoffrey Charles

Sirocco is a massively parallel, high performance storage system for the exascale era. It emphasizes client-to-client coordination, low server-side coupling, and free data movement to improve resilience and performance. Its architecture is inspired by peer-to-peer and victim- cache architectures. By leveraging these ideas, Sirocco natively supports several media types, including RAM, flash, disk, and archival storage, with automatic migration between levels. Sirocco also includes storage interfaces and support that are more advanced than typical block storage. Sirocco enables clients to efficiently use key-value storage or block-based storage with the same interface. It also provides several levels of transactional data updatesmore » within a single storage command, including full ACID-compliant updates. This transaction support extends to updating several objects within a single transaction. Further support is provided for con- currency control, enabling greater performance for workloads while providing safe concurrent modification. By pioneering these and other technologies and techniques in the storage system, Sirocco is poised to fulfill a need for a massively scalable, write-optimized storage system for exascale systems. This is version 1.0 of a document reflecting the current and planned state of Sirocco. Further versions of this document will be accessible at http://www.cs.sandia.gov/Scalable_IO/ sirocco .« less

Evaluation of improved land use and canopy representation in ...

EPA Pesticide Factsheets

Biogenic volatile organic compounds (BVOC) participate in reactions that can lead to secondarily formed ozone and particulate matter (PM) impacting air quality and climate. BVOC emissions are important inputs to chemical transport models applied on local to global scales but considerable uncertainty remains in the representation of canopy parameterizations and emission algorithms from different vegetation species. The Biogenic Emission Inventory System (BEIS) has been used to support both scientific and regulatory model assessments for ozone and PM. Here we describe a new version of BEIS which includes updated input vegetation data and canopy model formulation for estimating leaf temperature and vegetation data on estimated BVOC. The Biogenic Emission Landuse Database (BELD) was revised to incorporate land use data from the Moderate Resolution Imaging Spectroradiometer (MODIS) land product and 2006 National Land Cover Database (NLCD) land coverage. Vegetation species data are based on the US Forest Service (USFS) Forest Inventory and Analysis (FIA) version 5.1 for 2002–2013 and US Department of Agriculture (USDA) 2007 census of agriculture data. This update results in generally higher BVOC emissions throughout California compared with the previous version of BEIS. Baseline and updated BVOC emission estimates are used in Community Multiscale Air Quality (CMAQ) Model simulations with 4 km grid resolution and evaluated with measurements of isoprene and monoterp

Documentation for the machine-readable version of the SAO-HD-GC-DM cross index version 1983

NASA Technical Reports Server (NTRS)

Roman, N. G.; Warren, W. H., Jr.; Schofield, N., Jr.

1983-01-01

An updated and extended machine readable version of the Smithsonian Astrophysical Observatory star catalog (SAO) is described. A correction of all errors which were found since preparation of the original catalog which resulted from misidentifications and omissions of components in multiple star systems and missing Durchmusterung numbers (the common identifier) in the SAO Catalog are included and component identifications from the Index of Visual Double Stars (IDS) are appended to all multiple SAO entries with the same DM numbers, and lower case letter identifiers for supplemental BD stars are added. A total of 11,398 individual corrections and data additions is incorporated into the present version of the cross index.

NEQAIRv14.0 Release Notes: Nonequilibrium and Equilibrium Radiative Transport Spectra Program

NASA Technical Reports Server (NTRS)

Brandis, Aaron Michael; Cruden, Brett A.

2014-01-01

NEQAIR v14.0 is the first parallelized version of NEQAIR. Starting from the last version of the code that went through the internal software release process at NASA Ames (NEQAIR 2008), there have been significant updates to the physics in the code and the computational efficiency. NEQAIR v14.0 supersedes NEQAIR v13.2, v13.1 and the suite of NEQAIR2009 versions. These updates have predominantly been performed by Brett Cruden and Aaron Brandis from ERC Inc at NASA Ames Research Center in 2013 and 2014. A new naming convention is being adopted with this current release. The current and future versions of the code will be named NEQAIR vY.X. The Y will refer to a major release increment. Minor revisions and update releases will involve incrementing X. This is to keep NEQAIR more in line with common software release practices. NEQAIR v14.0 is a standalone software tool for line-by-line spectral computation of radiative intensities and/or radiative heat flux, with one-dimensional transport of radiation. In order to accomplish this, NEQAIR v14.0, as in previous versions, requires the specification of distances (in cm), temperatures (in K) and number densities (in parts/cc) of constituent species along lines of sight. Therefore, it is assumed that flow quantities have been extracted from flow fields computed using other tools, such as CFD codes like DPLR or LAURA, and that lines of sight have been constructed and written out in the format required by NEQAIR v14.0. There are two principal modes for running NEQAIR v14.0. In the first mode NEQAIR v14.0 is used as a tool for creating synthetic spectra of any desired resolution (including convolution with a specified instrument/slit function). The first mode is typically exercised in simulating/interpreting spectroscopic measurements of different sources (e.g. shock tube data, plasma torches, etc.). In the second mode, NEQAIR v14.0 is used as a radiative heat flux prediction tool for flight projects. Correspondingly, NEQAIR has also been used to simulate the radiance measured on previous flight missions. This report summarizes the database updates, corrections that have been made to the code, changes to input files, parallelization, the current usage recommendations, including test cases, and an indication of the performance enhancements achieved.

Research and development for Onboard Navigation (ONAV) ground based expert/trainer system: ONAV entry knowledge requirements specification update

NASA Technical Reports Server (NTRS)

Bochsler, Daniel C.

1988-01-01

A revised version of expert knowledge for the onboard navigation (ONAV) entry system is given. Included is some brief background information together with information describing the knowledge that the system does contain.

RCBI-II: The Second Revision of the Revised Cyber Bullying Inventory

ERIC Educational Resources Information Center

Topcu, Çigdem; Erdur-Baker, Özgür

2018-01-01

The aim of this study is to update the Turkish version of the Revised Cyber Bullying Inventory (RCBI) and eliminate specific technology names. Validity and reliability tests were carried out with 1,803 high school students. The updated version of the RCBI yields valid and reliable scores measuring cyberbullying and victimization.

A new version of the ERICA tool to facilitate impact assessments of radioactivity on wild plants and animals.

PubMed

Brown, J E; Alfonso, B; Avila, R; Beresford, N A; Copplestone, D; Hosseini, A

2016-03-01

A new version of the ERICA Tool (version 1.2) was released in November 2014; this constitutes the first major update of the Tool since release in 2007. The key features of the update are presented in this article. Of particular note are new transfer databases extracted from an international compilation of concentration ratios (CRwo-media) and the modification of 'extrapolation' approaches used to select transfer data in cases where information is not available. Bayesian updating approaches have been used in some cases to draw on relevant information that would otherwise have been excluded in the process of deriving CRwo-media statistics. All of these efforts have in turn led to the requirement to update Environmental Media Concentration Limits (EMCLs) used in Tier 1 assessments. Some of the significant changes with regard to EMCLs are highlighted. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

The National Shipbuilding Research Program, Proceedings of the REAPS Technical Symposium (2nd) held in Palm Beach Shores, Florida, on 24-25 Jun 1975: Full Proceedings

DTIC Science & Technology

1975-06-01

AUTOKON-71 System. Her major tasks include processing Analysis Requests, releasing new system versions, and coordinating program modifications. Some past...for deformed meshes; improvement of crane boom analysis test data and a post-pro- cessing program. I. BACKGROUND 1. What is the AUTOKON System n? a...updates to either enhance or correct the capa- bilities has been generated. Two major sources contribute these updates: the REAPS Analysis Request (AR

A Comparison of Modeled Pollutant Profiles With MOZAIC Aircraft Measurements

EPA Science Inventory

In this study, we use measurements performed under the MOZAIC program to evaluate vertical profiles of meteorological parameters, CO, and ozone that were simulated for the year 2006 with several versions of the WRF/CMAQ modeling system. Model updates, including WRF nudging strate...

The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Short Version).

PubMed

Sidhu, Paul S; Cantisani, Vito; Dietrich, Christoph F; Gilja, Odd Helge; Saftoiu, Adrian; Bartels, Eva; Bertolotto, Michele; Calliada, Fabrizio; Clevert, Dirk-André; Cosgrove, David; Deganello, Annamaria; D'Onofrio, Mirko; Drudi, Francesco Maria; Freeman, Simon; Harvey, Christopher; Jenssen, Christian; Jung, Ernst-Michael; Klauser, Andrea Sabine; Lassau, Nathalie; Meloni, Maria Franca; Leen, Edward; Nicolau, Carlos; Nolsoe, Christian; Piscaglia, Fabio; Prada, Francesco; Prosch, Helmut; Radzina, Maija; Savelli, Luca; Weskott, Hans-Peter; Wijkstra, Hessel

2018-04-01

The updated version of the EFSUMB guidelines on the application of non-hepatic contrast-enhanced ultrasound (CEUS) deals with the use of microbubble ultrasound contrast outside the liver in the many established and emerging applications. © Georg Thieme Verlag KG Stuttgart · New York.

Description and evaluation of the Community Multiscale Air ...

EPA Pesticide Factsheets

The Community Multiscale Air Quality (CMAQ) model is a comprehensive multipollutant air quality modeling system developed and maintained by the US Environmental Protection Agency's (EPA) Office of Research and Development (ORD). Recently, version 5.1 of the CMAQ model (v5.1) was released to the public, incorporating a large number of science updates and extended capabilities over the previous release version of the model (v5.0.2). These updates include the following: improvements in the meteorological calculations in both CMAQ and the Weather Research and Forecast (WRF) model used to provide meteorological fields to CMAQ, updates to the gas and aerosol chemistry, revisions to the calculations of clouds and photolysis, and improvements to the dry and wet deposition in the model. Sensitivity simulations isolating several of the major updates to the modeling system show that changes to the meteorological calculations result in enhanced afternoon and early evening mixing in the model, periods when the model historically underestimates mixing. This enhanced mixing results in higher ozone (O3) mixing ratios on average due to reduced NO titration, and lower fine particulate matter (PM2. 5) concentrations due to greater dilution of primary pollutants (e.g., elemental and organic carbon). Updates to the clouds and photolysis calculations greatly improve consistency between the WRF and CMAQ models and result in generally higher O3 mixing ratios, primarily due to reduced

Second Generation Integrated Composite Analyzer (ICAN) Computer Code

NASA Technical Reports Server (NTRS)

Murthy, Pappu L. N.; Ginty, Carol A.; Sanfeliz, Jose G.

1993-01-01

This manual updates the original 1986 NASA TP-2515, Integrated Composite Analyzer (ICAN) Users and Programmers Manual. The various enhancements and newly added features are described to enable the user to prepare the appropriate input data to run this updated version of the ICAN code. For reference, the micromechanics equations are provided in an appendix and should be compared to those in the original manual for modifications. A complete output for a sample case is also provided in a separate appendix. The input to the code includes constituent material properties, factors reflecting the fabrication process, and laminate configuration. The code performs micromechanics, macromechanics, and laminate analyses, including the hygrothermal response of polymer-matrix-based fiber composites. The output includes the various ply and composite properties, the composite structural response, and the composite stress analysis results with details on failure. The code is written in FORTRAN 77 and can be used efficiently as a self-contained package (or as a module) in complex structural analysis programs. The input-output format has changed considerably from the original version of ICAN and is described extensively through the use of a sample problem.

Nuclear Engine System Simulation (NESS). Version 2.0: Program user's guide

NASA Technical Reports Server (NTRS)

Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman

1993-01-01

This Program User's Guide discusses the Nuclear Thermal Propulsion (NTP) engine system design features and capabilities modeled in the Nuclear Engine System Simulation (NESS): Version 2.0 program (referred to as NESS throughout the remainder of this document), as well as its operation. NESS was upgraded to include many new modeling capabilities not available in the original version delivered to NASA LeRC in Dec. 1991, NESS's new features include the following: (1) an improved input format; (2) an advanced solid-core NERVA-type reactor system model (ENABLER 2); (3) a bleed-cycle engine system option; (4) an axial-turbopump design option; (5) an automated pump-out turbopump assembly sizing option; (6) an off-design gas generator engine cycle design option; (7) updated hydrogen properties; (8) an improved output format; and (9) personal computer operation capability. Sample design cases are presented in the user's guide that demonstrate many of the new features associated with this upgraded version of NESS, as well as design modeling features associated with the original version of NESS.

An update to the Surface Ocean CO2 Atlas (SOCAT version 2)

NASA Astrophysics Data System (ADS)

Bakker, D. C. E.; Pfeil, B.; Smith, K.; Hankin, S.; Olsen, A.; Alin, S. R.; Cosca, C.; Harasawa, S.; Kozyr, A.; Nojiri, Y.; O'Brien, K. M.; Schuster, U.; Telszewski, M.; Tilbrook, B.; Wada, C.; Akl, J.; Barbero, L.; Bates, N. R.; Boutin, J.; Bozec, Y.; Cai, W.-J.; Castle, R. D.; Chavez, F. P.; Chen, L.; Chierici, M.; Currie, K.; de Baar, H. J. W.; Evans, W.; Feely, R. A.; Fransson, A.; Gao, Z.; Hales, B.; Hardman-Mountford, N. J.; Hoppema, M.; Huang, W.-J.; Hunt, C. W.; Huss, B.; Ichikawa, T.; Johannessen, T.; Jones, E. M.; Jones, S. D.; Jutterström, S.; Kitidis, V.; Körtzinger, A.; Landschützer, P.; Lauvset, S. K.; Lefèvre, N.; Manke, A. B.; Mathis, J. T.; Merlivat, L.; Metzl, N.; Murata, A.; Newberger, T.; Omar, A. M.; Ono, T.; Park, G.-H.; Paterson, K.; Pierrot, D.; Ríos, A. F.; Sabine, C. L.; Saito, S.; Salisbury, J.; Sarma, V. V. S. S.; Schlitzer, R.; Sieger, R.; Skjelvan, I.; Steinhoff, T.; Sullivan, K. F.; Sun, H.; Sutton, A. J.; Suzuki, T.; Sweeney, C.; Takahashi, T.; Tjiputra, J.; Tsurushima, N.; van Heuven, S. M. A. C.; Vandemark, D.; Vlahos, P.; Wallace, D. W. R.; Wanninkhof, R.; Watson, A. J.

2014-03-01

The Surface Ocean CO2 Atlas (SOCAT), an activity of the international marine carbon research community, provides access to synthesis and gridded fCO2 (fugacity of carbon dioxide) products for the surface oceans. Version 2 of SOCAT is an update of the previous release (version 1) with more data (increased from 6.3 million to 10.1 million surface water fCO2 values) and extended data coverage (from 1968-2007 to 1968-2011). The quality control criteria, while identical in both versions, have been applied more strictly in version 2 than in version 1. The SOCAT website (http://www.socat.info/) has links to quality control comments, metadata, individual data set files, and synthesis and gridded data products. Interactive online tools allow visitors to explore the richness of the data. Applications of SOCAT include process studies, quantification of the ocean carbon sink and its spatial, seasonal, year-to-year and longerterm variation, as well as initialisation or validation of ocean carbon models and coupled climate-carbon models. Data coverage Repository-References: Individual data set files and synthesis product: doi:10.1594/PANGAEA.811776 Gridded products: doi:10.3334/CDIAC/OTG.SOCAT_V2_GRID Available at: http://www.socat.info/ Coverage: 79° S to 90° N; 180° W to 180° E Location Name: Global Oceans and Coastal Seas Date/Time Start: 16 November 1968 ate/Time End: 26 December 2011

Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) (Version 2) (External Review Draft)

EPA Science Inventory

EPA announced the availability of the draft report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) for a 30-day public comment period. The ICLUS version 2 (v2) modeling tool furthered land change mod...

P- and S-wave velocity models incorporating the Cascadia subduction zone for 3D earthquake ground motion simulations—Update for Open-File Report 2007–1348

USGS Publications Warehouse

Stephenson, William J.; Reitman, Nadine G.; Angster, Stephen J.

2017-12-20

In support of earthquake hazards studies and ground motion simulations in the Pacific Northwest, threedimensional (3D) P- and S-wave velocity (VP and VS , respectively) models incorporating the Cascadia subduction zone were previously developed for the region encompassed from about 40.2°N. to 50°N. latitude, and from about 122°W. to 129°W. longitude (fig. 1). This report describes updates to the Cascadia velocity property volumes of model version 1.3 ([V1.3]; Stephenson, 2007), herein called model version 1.6 (V1.6). As in model V1.3, the updated V1.6 model volume includes depths from 0 kilometers (km) (mean sea level) to 60 km, and it is intended to be a reference for researchers who have used, or are planning to use, this model in their earth science investigations. To this end, it is intended that the VP and VS property volumes of model V1.6 will be considered a template for a community velocity model of the Cascadia region as additional results become available. With the recent and ongoing development of the National Crustal Model (NCM; Boyd and Shah, 2016), we envision any future versions of this model will be directly integrated with that effort

Modelling the climate and surface mass balance of polar ice sheets using RACMO2 - Part 2: Antarctica (1979-2016)

NASA Astrophysics Data System (ADS)

Melchior van Wessem, Jan; van de Berg, Willem Jan; Noël, Brice P. Y.; van Meijgaard, Erik; Amory, Charles; Birnbaum, Gerit; Jakobs, Constantijn L.; Krüger, Konstantin; Lenaerts, Jan T. M.; Lhermitte, Stef; Ligtenberg, Stefan R. M.; Medley, Brooke; Reijmer, Carleen H.; van Tricht, Kristof; Trusel, Luke D.; van Ulft, Lambertus H.; Wouters, Bert; Wuite, Jan; van den Broeke, Michiel R.

2018-04-01

We evaluate modelled Antarctic ice sheet (AIS) near-surface climate, surface mass balance (SMB) and surface energy balance (SEB) from the updated polar version of the regional atmospheric climate model, RACMO2 (1979-2016). The updated model, referred to as RACMO2.3p2, incorporates upper-air relaxation, a revised topography, tuned parameters in the cloud scheme to generate more precipitation towards the AIS interior and modified snow properties reducing drifting snow sublimation and increasing surface snowmelt. Comparisons of RACMO2 model output with several independent observational data show that the existing biases in AIS temperature, radiative fluxes and SMB components are further reduced with respect to the previous model version. The model-integrated annual average SMB for the ice sheet including ice shelves (minus the Antarctic Peninsula, AP) now amounts to 2229 Gt y-1, with an interannual variability of 109 Gt y-1. The largest improvement is found in modelled surface snowmelt, which now compares well with satellite and weather station observations. For the high-resolution ( ˜ 5.5 km) AP simulation, results remain comparable to earlier studies. The updated model provides a new, high-resolution data set of the contemporary near-surface climate and SMB of the AIS; this model version will be used for future climate scenario projections in a forthcoming study.

Updated Chemical Kinetics and Sensitivity Analysis Code

NASA Technical Reports Server (NTRS)

Radhakrishnan, Krishnan

2005-01-01

An updated version of the General Chemical Kinetics and Sensitivity Analysis (LSENS) computer code has become available. A prior version of LSENS was described in "Program Helps to Determine Chemical-Reaction Mechanisms" (LEW-15758), NASA Tech Briefs, Vol. 19, No. 5 (May 1995), page 66. To recapitulate: LSENS solves complex, homogeneous, gas-phase, chemical-kinetics problems (e.g., combustion of fuels) that are represented by sets of many coupled, nonlinear, first-order ordinary differential equations. LSENS has been designed for flexibility, convenience, and computational efficiency. The present version of LSENS incorporates mathematical models for (1) a static system; (2) steady, one-dimensional inviscid flow; (3) reaction behind an incident shock wave, including boundary layer correction; (4) a perfectly stirred reactor; and (5) a perfectly stirred reactor followed by a plug-flow reactor. In addition, LSENS can compute equilibrium properties for the following assigned states: enthalpy and pressure, temperature and pressure, internal energy and volume, and temperature and volume. For static and one-dimensional-flow problems, including those behind an incident shock wave and following a perfectly stirred reactor calculation, LSENS can compute sensitivity coefficients of dependent variables and their derivatives, with respect to the initial values of dependent variables and/or the rate-coefficient parameters of the chemical reactions.

Practical Parenting Tips: Over 1,500 Helpful Hints for the First Five Years. Revised and Updated.

ERIC Educational Resources Information Center

Lansky, Vicki

Noting that other parents can be an excellent source of practical parenting advice, this book compiles over a thousand practical tips--those not generally found in baby care books or pediatrician's offices--with over 400 new tips compiled since the book's 1982 version. Major topics include: (1) new baby care, including cesarean deliveries,…

Focusing on Success: Examples of How the Universal Service Fund Is Helping Improve Connectivity across the Country

ERIC Educational Resources Information Center

Universal Service Administrative Company, 2008

2008-01-01

This report includes examples of how Universal Service Fund support is used by beneficiaries across the country. Included in this version are approximately 140 success stories of how the Universal Service Fund is helping to improve connectivity in the United States. This report is updated quarterly, as Universal Service Administrative Company…

Energy Efficiency: Transportation and Buildings

NASA Astrophysics Data System (ADS)

Lubell, Michael S.; Richter, Burton

2011-11-01

We present a condensed version of the American Physical Society's 2008 analysis of energy efficiency in the transportation and buildings sectors in the United States with updated numbers. In addition to presenting technical findings, we include the report's recommendations for policy makers that we believe are in the best interests of the nation.

NOAA's National Air Quality Prediction and Development of Aerosol and Atmospheric Composition Prediction Components for NGGPS

NASA Astrophysics Data System (ADS)

Stajner, I.; McQueen, J.; Lee, P.; Stein, A. F.; Wilczak, J. M.; Upadhayay, S.; daSilva, A.; Lu, C. H.; Grell, G. A.; Pierce, R. B.

2017-12-01

NOAA's operational air quality predictions of ozone, fine particulate matter (PM2.5) and wildfire smoke over the United States and airborne dust over the contiguous 48 states are distributed at http://airquality.weather.gov. The National Air Quality Forecast Capability (NAQFC) providing these predictions was updated in June 2017. Ozone and PM2.5 predictions are now produced using the system linking the Community Multiscale Air Quality model (CMAQ) version 5.0.2 with meteorological inputs from the North American Mesoscale Forecast System (NAM) version 4. Predictions of PM2.5 include intermittent dust emissions and wildfire emissions from an updated version of BlueSky system. For the latter, the CMAQ system is initialized by rerunning it over the previous 24 hours to include wildfire emissions at the time when they were observed from the satellites. Post processing to reduce the bias in PM2.5 prediction was updated using the Kalman filter analog (KFAN) technique. Dust related aerosol species at the CMAQ domain lateral boundaries now come from the NEMS Global Aerosol Component (NGAC) v2 predictions. Further development of NAQFC includes testing of CMAQ predictions to 72 hours, Canadian fire emissions data from Environment and Climate Change Canada (ECCC) and the KFAN technique to reduce bias in ozone predictions. NOAA is developing the Next Generation Global Predictions System (NGGPS) with an aerosol and gaseous atmospheric composition component to improve and integrate aerosol and ozone predictions and evaluate their impacts on physics, data assimilation and weather prediction. Efforts are underway to improve cloud microphysics, investigate aerosol effects and include representations of atmospheric composition of varying complexity into NGGPS: from the operational ozone parameterization, GOCART aerosols, with simplified ozone chemistry, to CMAQ chemistry with aerosol modules. We will present progress on community building, planning and development of NGGPS.

Additional development of the XTRAN3S computer program

NASA Technical Reports Server (NTRS)

Borland, C. J.

1989-01-01

Additional developments and enhancements to the XTRAN3S computer program, a code for calculation of steady and unsteady aerodynamics, and associated aeroelastic solutions, for 3-D wings in the transonic flow regime are described. Algorithm improvements for the XTRAN3S program were provided including an implicit finite difference scheme to enhance the allowable time step and vectorization for improved computational efficiency. The code was modified to treat configurations with a fuselage, multiple stores/nacelles/pylons, and winglets. Computer program changes (updates) for error corrections and updates for version control are provided.

NCCN Guidelines Insights: Bladder Cancer, Version 2.2016.

PubMed

Clark, Peter E; Spiess, Philippe E; Agarwal, Neeraj; Bangs, Rick; Boorjian, Stephen A; Buyyounouski, Mark K; Efstathiou, Jason A; Flaig, Thomas W; Friedlander, Terence; Greenberg, Richard E; Guru, Khurshid A; Hahn, Noah; Herr, Harry W; Hoimes, Christopher; Inman, Brant A; Kader, A Karim; Kibel, Adam S; Kuzel, Timothy M; Lele, Subodh M; Meeks, Joshua J; Michalski, Jeff; Montgomery, Jeffrey S; Pagliaro, Lance C; Pal, Sumanta K; Patterson, Anthony; Petrylak, Daniel; Plimack, Elizabeth R; Pohar, Kamal S; Porter, Michael P; Sexton, Wade J; Siefker-Radtke, Arlene O; Sonpavde, Guru; Tward, Jonathan; Wile, Geoffrey; Dwyer, Mary A; Smith, Courtney

2016-10-01

These NCCN Guidelines Insights discuss the major recent updates to the NCCN Guidelines for Bladder Cancer based on the review of the evidence in conjunction with the expert opinion of the panel. Recent updates include (1) refining the recommendation of intravesical bacillus Calmette-Guérin, (2) strengthening the recommendations for perioperative systemic chemotherapy, and (3) incorporating immunotherapy into second-line therapy for locally advanced or metastatic disease. These NCCN Guidelines Insights further discuss factors that affect integration of these recommendations into clinical practice. Copyright © 2016 by the National Comprehensive Cancer Network.

Cosmic-ray propagation with DRAGON2: I. numerical solver and astrophysical ingredients

NASA Astrophysics Data System (ADS)

Evoli, Carmelo; Gaggero, Daniele; Vittino, Andrea; Di Bernardo, Giuseppe; Di Mauro, Mattia; Ligorini, Arianna; Ullio, Piero; Grasso, Dario

2017-02-01

We present version 2 of the DRAGON code designed for computing realistic predictions of the CR densities in the Galaxy. The code numerically solves the interstellar CR transport equation (including inhomogeneous and anisotropic diffusion, either in space and momentum, advective transport and energy losses), under realistic conditions. The new version includes an updated numerical solver and several models for the astrophysical ingredients involved in the transport equation. Improvements in the accuracy of the numerical solution are proved against analytical solutions and in reference diffusion scenarios. The novel features implemented in the code allow to simulate the diverse scenarios proposed to reproduce the most recent measurements of local and diffuse CR fluxes, going beyond the limitations of the homogeneous galactic transport paradigm. To this end, several applications using DRAGON2 are presented as well. This new version facilitates the users to include their own physical models by means of a modular C++ structure.

THE NASA AMES PAH IR SPECTROSCOPIC DATABASE VERSION 2.00: UPDATED CONTENT, WEB SITE, AND ON(OFF)LINE TOOLS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boersma, C.; Mattioda, A. L.; Allamandola, L. J.

A significantly updated version of the NASA Ames PAH IR Spectroscopic Database, the first major revision since its release in 2010, is presented. The current version, version 2.00, contains 700 computational and 75 experimental spectra compared, respectively, with 583 and 60 in the initial release. The spectra span the 2.5-4000 μm (4000-2.5 cm{sup -1}) range. New tools are available on the site that allow one to analyze spectra in the database and compare them with imported astronomical spectra as well as a suite of IDL object classes (a collection of programs utilizing IDL's object-oriented programming capabilities) that permit offline analysismore » called the AmesPAHdbIDLSuite. Most noteworthy among the additions are the extension of the computational spectroscopic database to include a number of significantly larger polycyclic aromatic hydrocarbons (PAHs), the ability to visualize the molecular atomic motions corresponding to each vibrational mode, and a new tool that allows one to perform a non-negative least-squares fit of an imported astronomical spectrum with PAH spectra in the computational database. Finally, a methodology is described in the Appendix, and implemented using the AmesPAHdbIDLSuite, that allows the user to enforce charge balance during the fitting procedure.« less

Chemical transport model simulations of organic aerosol in southern California: model evaluation and gasoline and diesel source contributions

NASA Astrophysics Data System (ADS)

Jathar, Shantanu H.; Woody, Matthew; Pye, Havala O. T.; Baker, Kirk R.; Robinson, Allen L.

2017-03-01

Gasoline- and diesel-fueled engines are ubiquitous sources of air pollution in urban environments. They emit both primary particulate matter and precursor gases that react to form secondary particulate matter in the atmosphere. In this work, we updated the organic aerosol module and organic emissions inventory of a three-dimensional chemical transport model, the Community Multiscale Air Quality Model (CMAQ), using recent, experimentally derived inputs and parameterizations for mobile sources. The updated model included a revised volatile organic compound (VOC) speciation for mobile sources and secondary organic aerosol (SOA) formation from unspeciated intermediate volatility organic compounds (IVOCs). The updated model was used to simulate air quality in southern California during May and June 2010, when the California Research at the Nexus of Air Quality and Climate Change (CalNex) study was conducted. Compared to the Traditional version of CMAQ, which is commonly used for regulatory applications, the updated model did not significantly alter the predicted organic aerosol (OA) mass concentrations but did substantially improve predictions of OA sources and composition (e.g., POA-SOA split), as well as ambient IVOC concentrations. The updated model, despite substantial differences in emissions and chemistry, performed similar to a recently released research version of CMAQ (Woody et al., 2016) that did not include the updated VOC and IVOC emissions and SOA data. Mobile sources were predicted to contribute 30-40 % of the OA in southern California (half of which was SOA), making mobile sources the single largest source contributor to OA in southern California. The remainder of the OA was attributed to non-mobile anthropogenic sources (e.g., cooking, biomass burning) with biogenic sources contributing to less than 5 % to the total OA. Gasoline sources were predicted to contribute about 13 times more OA than diesel sources; this difference was driven by differences in SOA production. Model predictions highlighted the need to better constrain multi-generational oxidation reactions in chemical transport models.

Updating sea spray aerosol emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2

EPA Pesticide Factsheets

The uploaded data consists of the BRACE Na aerosol observations paired with CMAQ model output, the updated model's parameterization of sea salt aerosol emission size distribution, and the model's parameterization of the sea salt emission factor as a function of sea surface temperature. This dataset is associated with the following publication:Gantt , B., J. Kelly , and J. Bash. Updating sea spray aerosol emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2. Geoscientific Model Development. Copernicus Publications, Katlenburg-Lindau, GERMANY, 8: 3733-3746, (2015).

What's new in the Atmospheric Model Evaluation Tool (AMET) version 1.3

EPA Science Inventory

A new version of the Atmospheric Model Evaluation Tool (AMET) has been released. The new version of AMET, version 1.3 (AMETv1.3), contains a number of updates and changes from the previous of version of AMET (v1.2) released in 2012. First, the Perl scripts used in the previous ve...

Differences and discrepancies between 2005 and 2008 Abbreviated Injury Scale versions - time to standardise

PubMed Central

2012-01-01

The aim of this letter is to facilitate the standardisation of Abbreviated Injury Scale (AIS) codesets used to code injuries in trauma registries. We have compiled a definitive list of the changes which have been implemented between the AIS 2005 and Update 2008 versions. While the AIS 2008 codeset appears to have remained consistent since its release, we have identified discrepancies between the codesets in copies of AIS 2005 dictionaries. As a result, we recommend that use of the AIS 2005 should be discontinued in favour of the Update 2008 version. PMID:22301065

Differences and discrepancies between 2005 and 2008 Abbreviated Injury Scale versions - time to standardise.

PubMed

Ringdal, Kjetil G; Hestnes, Morten; Palmer, Cameron S

2012-02-02

The aim of this letter is to facilitate the standardisation of Abbreviated Injury Scale (AIS) codesets used to code injuries in trauma registries. We have compiled a definitive list of the changes which have been implemented between the AIS 2005 and Update 2008 versions. While the AIS 2008 codeset appears to have remained consistent since its release, we have identified discrepancies between the codesets in copies of AIS 2005 dictionaries. As a result, we recommend that use of the AIS 2005 should be discontinued in favour of the Update 2008 version.

An evaluation of Lake States STEMS85.

Treesearch

Margaret R. Holdaway

1986-01-01

An updated version of the Lake States variant of STEMS is evaluated and compared with the previous version. The new version is slightly more accurate and precise. The strengths and weaknesses of this tree growth projection system are also identified.

NASA Releases 'NASA App HD' for iPad

NASA Image and Video Library

2012-07-06

The NASA App HD invites you to discover a wealth of NASA information right on your iPad. The application collects, customizes and delivers an extensive selection of dynamically updated mission information, images, videos and Twitter feeds from various online NASA sources in a convenient mobile package. Come explore with NASA, now on your iPad. 2012 Updated Version - HD Resolution and new features. Original version published on Sept. 1, 2010.

VizieR Online Data Catalog: Spectroscopically identified white dwarfs (McCook+, 2014)

NASA Astrophysics Data System (ADS)

McCook, G. P.; Sion, E. M.

2016-10-01

This is an update of the Villanova catalog published in the ApJS paper, corresponding to the Web version of the catalog in Apr 2014 (see http://www.astronomy.villanova.edu/WDCatalog/index.html). The introduction to the 1999 catalog is in the file "preface.tex". This updated version lists 14294 unique white dwarfs for a total of 27975 rows (multiple observations). (5 data files).

Agentless Cloud-Wide Monitoring of Virtual Disk State

DTIC Science & Technology

2015-10-01

packages include Apache, MySQL , PHP, Ruby on Rails, Java Application Servers, and many others. Figure 2.12 shows the results of a run of the Software...Linux, Apache, MySQL , PHP (LAMP) set of applications. Thus, many file-level update logs will contain the same versions of files repeated across many

Using Novel Word Context Measures to Predict Human Ratings of Lexical Proficiency

ERIC Educational Resources Information Center

Berger, Cynthia M.; Crossley, Scott A.; Kyle, Kristopher

2017-01-01

This study introduces a model of lexical proficiency based on novel computational indices related to word context. The indices come from an updated version of the Tool for the Automatic Analysis of Lexical Sophistication (TAALES) and include associative, lexical, and semantic measures of word context. Human ratings of holistic lexical proficiency…

UCbase 2.0: ultraconserved sequences database (2014 update)

PubMed Central

Lomonaco, Vincenzo; Martoglia, Riccardo; Mandreoli, Federica; Anderlucci, Laura; Emmett, Warren; Bicciato, Silvio; Taccioli, Cristian

2014-01-01

UCbase 2.0 (http://ucbase.unimore.it) is an update, extension and evolution of UCbase, a Web tool dedicated to the analysis of ultraconserved sequences (UCRs). UCRs are 481 sequences >200 bases sharing 100% identity among human, mouse and rat genomes. They are frequently located in genomic regions known to be involved in cancer or differentially expressed in human leukemias and carcinomas. UCbase 2.0 is a platform-independent Web resource that includes the updated version of the human genome annotation (hg19), information linking disorders to chromosomal coordinates based on the Systematized Nomenclature of Medicine classification, a query tool to search for Single Nucleotide Polymorphisms (SNPs) and a new text box to directly interrogate the database using a MySQL interface. To facilitate the interactive visual interpretation of UCR chromosomal positioning, UCbase 2.0 now includes a graph visualization interface directly linked to UCSC genome browser. Database URL: http://ucbase.unimore.it PMID:24951797

Quick Overview Scout 2008 Version 1.0

EPA Science Inventory

The Scout 2008 version 1.0 statistical software package has been updated from past DOS and Windows versions to provide classical and robust univariate and multivariate graphical and statistical methods that are not typically available in commercial or freeware statistical softwar...

The UMIST database for astrochemistry 2006

NASA Astrophysics Data System (ADS)

Woodall, J.; Agúndez, M.; Markwick-Kemper, A. J.; Millar, T. J.

2007-05-01

Aims:We present a new version of the UMIST Database for Astrochemistry, the fourth such version to be released to the public. The current version contains some 4573 binary gas-phase reactions, an increase of 10% from the previous (1999) version, among 420 species, of which 23 are new to the database. Methods: Major updates have been made to ion-neutral reactions, neutral-neutral reactions, particularly at low temperature, and dissociative recombination reactions. We have included for the first time the interstellar chemistry of fluorine. In addition to the usual database, we have also released a reaction set in which the effects of dipole-enhanced ion-neutral rate coefficients are included. Results: These two reactions sets have been used in a dark cloud model and the results of these models are presented and discussed briefly. The database and associated software are available on the World Wide Web at www.udfa.net. Tables 1, 2, 4 and 9 are only available in electronic form at http://www.aanda.org

Comparison of updates to the Molly cow model to predict methane production from dairy cows fed pasture.

PubMed

Gregorini, P; Beukes, P C; Hanigan, M D; Waghorn, G; Muetzel, S; McNamara, J P

2013-08-01

Molly is a deterministic, mechanistic, dynamic model representing the digestion, metabolism, and production of a dairy cow. This study compared the predictions of enteric methane production from the original version of Molly (MollyOrigin) and 2 new versions of Molly. Updated versions included new ruminal fiber digestive parameters and animal hormonal parameters (Molly84) and a revised version of digestive and ruminal parameters (Molly85), using 3 different ruminal volatile fatty acid (VFA) stoichiometry constructs to describe the VFA pattern and methane (CH4) production (g of CH4/d). The VFA stoichiometry constructs were the original forage and mixed-diet VFA constructs and a new VFA stoichiometry based on a more recent and larger set of data that includes lactate and valerate production, amylolytic and cellulolytic bacteria, as well as protozoal pools. The models' outputs were challenged using data from 16 dairy cattle 26 mo old [standard error of the mean (SEM)=1.7], 82 (SEM=8.7) d in milk, producing 17 (SEM=0.2) kg of milk/d, and fed fresh-cut ryegrass [dry matter intake=12.3 (SEM=0.3) kg of DM/d] in respiration chambers. Mean observed CH4 production was 266±5.6 SEM (g/d). Mean predicted values for CH4 production were 287 and 258 g/d for MollyOrigin without and with the new VFA construct. Model Molly84 predicted 295 and 288 g of CH4/d with and without the new VFA settings. Model Molly85 predicted the same CH4 production (276 g/d) with or without the new VFA construct. The incorporation of the new VFA construct did not consistently reduce the low prediction error across the versions of Molly evaluated in the present study. The improvements in the Molly versions from MollyOrigin to Molly84 to Molly85 resulted in a decrease in mean square prediction error from 8.6 to 8.3 to 4.3% using the forage diet setting. The majority of the mean square prediction error was apportioned to random bias (e.g., 43, 65, and 70% in MollyOrigin, Molly84, and Molly85, respectively, on the forage setting, showing that with the updated versions a greater proportion of error was random). The slope bias was less than 2% in all cases. We concluded that, of the versions of Molly used for pastoral systems, Molly85 has the capability to predict CH4 production from grass-fed dairy cows with the highest accuracy. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

PRMS-IV, the precipitation-runoff modeling system, version 4

USGS Publications Warehouse

Markstrom, Steven L.; Regan, R. Steve; Hay, Lauren E.; Viger, Roland J.; Webb, Richard M.; Payn, Robert A.; LaFontaine, Jacob H.

2015-01-01

Computer models that simulate the hydrologic cycle at a watershed scale facilitate assessment of variability in climate, biota, geology, and human activities on water availability and flow. This report describes an updated version of the Precipitation-Runoff Modeling System. The Precipitation-Runoff Modeling System is a deterministic, distributed-parameter, physical-process-based modeling system developed to evaluate the response of various combinations of climate and land use on streamflow and general watershed hydrology. Several new model components were developed, and all existing components were updated, to enhance performance and supportability. This report describes the history, application, concepts, organization, and mathematical formulation of the Precipitation-Runoff Modeling System and its model components. This updated version provides improvements in (1) system flexibility for integrated science, (2) verification of conservation of water during simulation, (3) methods for spatial distribution of climate boundary conditions, and (4) methods for simulation of soil-water flow and storage.

European guidelines for workplace drug testing in urine.

PubMed

Taskinen, Sanna; Beck, Olof; Bosch, Tessa; Brcak, Michaela; Carmichael, Duncan; Fucci, Nadia; George, Claire; Piper, Mark; Salomone, Alberto; Schielen, Wim; Steinmeyer, Stefan; Weinmann, Wolfgang

2017-06-01

These European Guidelines for Workplace Drug Testing in Urine have been prepared and updated by the European Workplace Drug Testing Society (EWDTS). The first version of these urine guidelines was published in 2002. Since then, the guidelines have been followed by many laboratories in different European countries and their role has been essential particularly in countries lacking legislation for workplace drug testing. In 2014, the EWDTS started a guidelines updating project and published a new version of the urine guidelines in 2015. Here we represent this updated version of the urine guidelines. The European Guidelines are designed to establish best practice procedures whilst allowing individual countries to operate within the requirements of national customs and legislation. The EWDTS recommends that all European laboratories that undertake legally defensible workplace drug testing should use these guidelines as a template for accreditation. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Vectorized schemes for conical potential flow using the artificial density method

NASA Technical Reports Server (NTRS)

Bradley, P. F.; Dwoyer, D. L.; South, J. C., Jr.; Keen, J. M.

1984-01-01

A method is developed to determine solutions to the full-potential equation for steady supersonic conical flow using the artificial density method. Various update schemes used generally for transonic potential solutions are investigated. The schemes are compared for speed and robustness. All versions of the computer code have been vectorized and are currently running on the CYBER-203 computer. The update schemes are vectorized, where possible, either fully (explicit schemes) or partially (implicit schemes). Since each version of the code differs only by the update scheme and elements other than the update scheme are completely vectorizable, comparisons of computational effort and convergence rate among schemes are a measure of the specific scheme's performance. Results are presented for circular and elliptical cones at angle of attack for subcritical and supercritical crossflows.

Epi info - present and future.

PubMed

Su, Y; Yoon, S S

2003-01-01

Epi Info is a suite of public domain computer programs for public health professionals developed by the Centers for Disease Control and Prevention (CDC). Epi Info is used for rapid questionnaire design, data entry and validation, data analysis including mapping and graphing, and creation of reports. Epi Info was originally created in 1985 using Turbo Pascal. In 1998, the last version of Epi Info for DOS, version 6, was released. Epi Info for DOS is currently supported by CDC but is no longer updated. The current version, Epi Info 2002, is Windows-based software developed using Microsoft Visual Basic. Approximately 300,000 downloads of Epi Info software occurred in 2002 from approximately 130 countries. These numbers make Epi Info probably one of the most widely distributed and used public domain programs in the world. The DOS version of Epi Info was translated into 13 languages, and efforts are underway to translate the Windows version into other major languages. Versions already exist for Spanish, French, Portuguese, Chinese, Japanese, and Arabic.

The Fire INventory from NCAR (FINN): a high resolution global model to estimate the emissions from open burning

Treesearch

C. Wiedinmyer; S. K. Akagi; R. J. Yokelson; L. K. Emmons; J. A. Al-Saadi; J. J. Orlando; A. J. Soja

2010-01-01

The Fire INventory from NCAR version 1.0 (FINNv1) provides daily, 1 km resolution, global estimates of the trace gas and particle emissions from open burning of biomass, which includes wildfire, agricultural fires, and prescribed burning and does not include 5 biofuel use and trash burning. Emission factors used in the calculations have been updated with recent data,...

QDENSITY—A Mathematica quantum computer simulation

NASA Astrophysics Data System (ADS)

Juliá-Díaz, Bruno; Burdis, Joseph M.; Tabakin, Frank

2009-03-01

This Mathematica 6.0 package is a simulation of a Quantum Computer. The program provides a modular, instructive approach for generating the basic elements that make up a quantum circuit. The main emphasis is on using the density matrix, although an approach using state vectors is also implemented in the package. The package commands are defined in Qdensity.m which contains the tools needed in quantum circuits, e.g., multiqubit kets, projectors, gates, etc. New version program summaryProgram title: QDENSITY 2.0 Catalogue identifier: ADXH_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADXH_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 26 055 No. of bytes in distributed program, including test data, etc.: 227 540 Distribution format: tar.gz Programming language: Mathematica 6.0 Operating system: Any which supports Mathematica; tested under Microsoft Windows XP, Macintosh OS X, and Linux FC4 Catalogue identifier of previous version: ADXH_v1_0 Journal reference of previous version: Comput. Phys. Comm. 174 (2006) 914 Classification: 4.15 Does the new version supersede the previous version?: Offers an alternative, more up to date, implementation Nature of problem: Analysis and design of quantum circuits, quantum algorithms and quantum clusters. Solution method: A Mathematica package is provided which contains commands to create and analyze quantum circuits. Several Mathematica notebooks containing relevant examples: Teleportation, Shor's Algorithm and Grover's search are explained in detail. A tutorial, Tutorial.nb is also enclosed. Reasons for new version: The package has been updated to make it fully compatible with Mathematica 6.0 Summary of revisions: The package has been updated to make it fully compatible with Mathematica 6.0 Running time: Most examples included in the package, e.g., the tutorial, Shor's examples, Teleportation examples and Grover's search, run in less than a minute on a Pentium 4 processor (2.6 GHz). The running time for a quantum computation depends crucially on the number of qubits employed.

Documentation of the dynamic parameter, water-use, stream and lake flow routing, and two summary output modules and updates to surface-depression storage simulation and initial conditions specification options with the Precipitation-Runoff Modeling System (PRMS)

USGS Publications Warehouse

Regan, R. Steve; LaFontaine, Jacob H.

2017-10-05

This report documents seven enhancements to the U.S. Geological Survey (USGS) Precipitation-Runoff Modeling System (PRMS) hydrologic simulation code: two time-series input options, two new output options, and three updates of existing capabilities. The enhancements are (1) new dynamic parameter module, (2) new water-use module, (3) new Hydrologic Response Unit (HRU) summary output module, (4) new basin variables summary output module, (5) new stream and lake flow routing module, (6) update to surface-depression storage and flow simulation, and (7) update to the initial-conditions specification. This report relies heavily upon U.S. Geological Survey Techniques and Methods, book 6, chapter B7, which documents PRMS version 4 (PRMS-IV). A brief description of PRMS is included in this report.

Planetary Mission Entry Vehicles Quick Reference Guide. Version 3.0

NASA Technical Reports Server (NTRS)

Davies, Carol; Arcadi, Marla

2006-01-01

This is Version 3.0 of the planetary mission entry vehicle document. Three new missions, Re-entry F, Hayabusa, and ARD have been added to t he previously published edition (Version 2.1). In addition, the Huyge ns mission has been significantly updated and some Apollo data correc ted. Due to the changing nature of planetary vehicles during the desi gn, manufacture and mission phases, and to the variables involved in measurement and computation, please be aware that the data provided h erein cannot be guaranteed. Contact Carol Davies at cdavies@mail.arc. nasa.gov to correct or update the current data, or to suggest other missions.

Evaluating Surface Flux Results from CERES-FLASHFlux

NASA Technical Reports Server (NTRS)

Wilber, Anne C.; Stackhouse, Paul W., Jr.; Kratz, David P.; Gupta, Shashi K.; Sawaengphokhai, Parnchai K.

2015-01-01

The Fast Longwave and Shortwave Radiative Flux (FLASHFlux) data product was developed to provide a rapid release version of the Clouds and Earth's Radiant Energy System (CERES) results, which could be made available to the research and applications communities within one week of the satellite observations by exchanging some accuracy for speed of processing. Unlike standard CERES products, FLASHFlux does not maintain a long-term consistent record. Therefore the latest algorithm changes and input data can be incorporated into processing. FLASHFlux released Version3A (January 2013) and Version 3B (August 2014) which include the latest meteorological product from Global Modeling and Assimilation Office (GMAO), GEOS FP-IT (5.9.1), the latest spectral response functions and gains for the CERES instruments, and aerosol climatology based on the latest MATCH data. Version 3B included a slightly updated calibration and some changes to the surface albedo over snow/ice. Typically FLASHFlux does not reprocess earlier versions when a new version is released. The combined record of Time Interpolated Space Averaged (TISA) surface flux results from Versions3A and 3B for July 2012 to October 2015 have been compared to the ground-based measurements. The FLASHFlux results are also compared to two other CERES gridded products, SYN1deg and EBAF surface fluxes.

Investigating the Impact on Modeled Ozone Concentrations Using Meteorological Fields From WRF With and Updated Four-Dimensional Data Assimilation Approach”

EPA Science Inventory

The four-dimensional data assimilation (FDDA) technique in the Weather Research and Forecasting (WRF) meteorological model has recently undergone an important update from the original version. Previous evaluation results have demonstrated that the updated FDDA approach in WRF pr...

Updating national standards for drinking-water: a Philippine experience.

PubMed

Lomboy, M; Riego de Dios, J; Magtibay, B; Quizon, R; Molina, V; Fadrilan-Camacho, V; See, J; Enoveso, A; Barbosa, L; Agravante, A

2017-04-01

The latest version of the Philippine National Standards for Drinking-Water (PNSDW) was issued in 2007 by the Department of Health (DOH). Due to several issues and concerns, the DOH decided to make an update which is relevant and necessary to meet the needs of the stakeholders. As an output, the water quality parameters are now categorized into mandatory, primary, and secondary. The ten mandatory parameters are core parameters which all water service providers nationwide are obligated to test. These include thermotolerant coliforms or Escherichia coli, arsenic, cadmium, lead, nitrate, color, turbidity, pH, total dissolved solids, and disinfectant residual. The 55 primary parameters are site-specific and can be adopted as enforceable parameters when developing new water sources or when the existing source is at high risk of contamination. The 11 secondary parameters include operational parameters and those that affect the esthetic quality of drinking-water. In addition, the updated PNSDW include new sections: (1) reporting and interpretation of results and corrective actions; (2) emergency drinking-water parameters; (3) proposed Sustainable Development Goal parameters; and (4) standards for other drinking-water sources. The lessons learned and insights gained from the updating of standards are likewise incorporated in this paper.

Pesticide Electronic Application Submission Portal Updated with New Features

EPA Pesticide Factsheets

EPA has published an updated version of the Pesticide Submission Portal. This Web-based system for electronic submission of pesticide registration applications to EPA, with new features and functionality.

65 Years of Reprocessed GLDAS Version 2.0 Data and Their Exploration Using the NASA GES DISC Giovanni

NASA Technical Reports Server (NTRS)

Rui, Hualan; Vollmer, B.; Teng, W.; Beaudoing, H.; Rodell, M.; Silberstein, D.

2015-01-01

GLDAS-2.0 data have been reprocessed with updated Princeton meteorological forcing data within the Land Information System (LIS) Version 7, and temporal coverage have been extended to 1948-2012.Global Land Data Assimilation System Version 2 (GLDAS-2) has two components: GLDAS-2.0: entirely forced with the Princeton meteorological forcing data GLDAS-2.1: forced with atmospheric analysis and observation-based data after 2001In order to create more climatologically consistent data sets, NASA GSFC's Hydrological Sciences Laboratory (HSL) has recently reprocessed the GLDAS-2.0, by using updated Princeton meteorological forcing data within the LIS Version 7.GLDAS-2.0 data and data services are provided at NASA GES DISC Hydrology Data and Information Services Center (HDISC), in collaboration with HSL.

The Factor Structure of the CIBS-II-Readiness Assessment

ERIC Educational Resources Information Center

Gotch, Chad M.; French, Brian F.

2011-01-01

The Brigance Comprehensive Inventory of Basic Skills-II (CIBS-II)-Readiness form is a diagnostic battery intended for children aged 5 and 6 years. The CIBS-II-Readiness is a new version of the CIBS-Revised-Readiness and includes updated normative information on a larger representative sample in comparison to the CIBS-Revised-Readiness. Empirical…

76 FR 81437 - Proposed Significant New Use Rule for Phenol, 2,4-dimethyl-6-(1-methylpentadecyl)-

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-28

... Activity Relationships (EcoSAR) dataset for phenols has been significantly updated to include 203 chemicals... result, when the most recent version of EcoSAR was run for phenol, 2,4-dimethyl-6-(1-methylpentadecyl... the new EcoSAR prediction of no expected acute or chronic adverse ecological effects. Therefore, based...

Seafloor mapping and benthic habitat GIS for southern California, volume III

USGS Publications Warehouse

Cochrane, Guy R.; Golden, Nadine E.; Dartnell, Pete; Schroeder, Donna M.; Finlayson, David P.

2007-01-01

From August 8-27, 2005, more than 75 km of the continental shelf (Fig. 1) in water depths of 20-70m southeast of Santa Barbara, were surveyed during the USGS cruise S-1-05-SC (http://walrus.wr.usgs.gov/infobank/s/s105sc/html/s-1-05-sc.meta.html). Both Interferometric sonar and 14 hours of both vertical and oblique georeferenced submarine digital video were collected to (1) obtain geophysical data (bathymetry and acoustic reflectance), (2) examine and record geologic characteristics of the sea floor, and (3) construct maps of seafloor geomorphology and habitat distribution. Substrate distribution is predicted using a modified version of Cochrane and Lafferty (2002) video-supervised statistical classification of sonar data that includes derivatives of bathymetry data. Specific details of the methods can be found in the meatadata of the bathymetry data file. Substrates observed are predominantly sand with some rock. Rocky substrates were restricted primarily to an east-west trending bathymetric high 2,000 m north of oil platforms. This is an updated report (version 2.0) from the earlier 2007-1271 (version 1.0) open-file report. This updated report re-releases the data files in UTM, zone 11, WGS84 coordinates. Also, the bathymetry data has been corrected for a vertical offset discovered in the earlier 2007-1271 (version 1.0) report.

The Operation IceBridge Sea Ice Freeboard, Snow Septh and Thickness Product: An In-Depth Look at Past, Current and Future Versions

NASA Astrophysics Data System (ADS)

Harbeck, J.; Kurtz, N. T.; Studinger, M.; Onana, V.; Yi, D.

2015-12-01

The NASA Operation IceBridge Project Science Office has recently released an updated version of the sea ice freeboard, snow depth and thickness product (IDCSI4). This product is generated through the combination of multiple IceBridge instrument data, primarily the ATM laser altimeter, DMS georeferenced imagery and the CReSIS snow radar, and is available on a campaign-specific basis as all upstream data sets become available. Version 1 data (IDCSI2) was the initial data production; we have subsequently received community feedback that has now been incorporated, allowing us to provide an improved data product. All data now available to the public at the National Snow and Ice Data Center (NSIDC) have been homogeneously reprocessed using the new IDCSI4 algorithm. This algorithm contains significant upgrades that improve the quality and consistency of the dataset, including updated atmospheric and oceanic tidal models and replacement of the geoid with a more representative mean sea surface height product. Known errors with the IDCSI2 algorithm, identified by the Project Science Office as well as feedback from the scientific community, have been incorporated into the new algorithm as well. We will describe in detail the various steps of the IDCSI4 algorithm, show the improvements made over the IDCSI2 dataset and their beneficial impact and discuss future upgrades planned for the next version.

Author Correction: Re-examination of the relationship between marine virus and microbial cell abundances.

PubMed

Wigington, Charles H; Sonderegger, Derek; Brussaard, Corina P D; Buchan, Alison; Finke, Jan F; Fuhrman, Jed A; Lennon, Jay T; Middelboe, Mathias; Suttle, Curtis A; Stock, Charles; Wilson, William H; Wommack, K Eric; Wilhelm, Steven W; Weitz, Joshua S

2017-11-01

The original publication of this Article included analysis of virus and microbial cell abundances and virus-to-microbial cell ratios. Data in the Article came from 25 studies intended to be exclusively from marine sites. However, 3 of the studies included in the original unified dataset were erroneously classified as marine sites during compilation. The records with mis-recorded longitude and latitude values were, in fact, taken from inland, freshwater sources. The three inland, freshwater datasets are ELA, TROUT and SWAT. The data from these three studies represent 163 of the 5,671 records in the original publication. In the updated version of the Article, all analyses have been recalculated using the same statistical analysis pipeline released via GitHub as part of the original publication. Removal of the three studies reduces the unified dataset to 5,508 records. Analyses involving all grouped datasets have been updated with changes noted in each figure. All key results remain qualitatively unchanged. All data and scripts used in this correction have been made available as a new, updated GitHub release to reflect the updated dataset and figures.

Cosmic-ray propagation with DRAGON2: I. numerical solver and astrophysical ingredients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Evoli, Carmelo; Gaggero, Daniele; Vittino, Andrea

2017-02-01

We present version 2 of the DRAGON code designed for computing realistic predictions of the CR densities in the Galaxy. The code numerically solves the interstellar CR transport equation (including inhomogeneous and anisotropic diffusion, either in space and momentum, advective transport and energy losses), under realistic conditions. The new version includes an updated numerical solver and several models for the astrophysical ingredients involved in the transport equation. Improvements in the accuracy of the numerical solution are proved against analytical solutions and in reference diffusion scenarios. The novel features implemented in the code allow to simulate the diverse scenarios proposed tomore » reproduce the most recent measurements of local and diffuse CR fluxes, going beyond the limitations of the homogeneous galactic transport paradigm. To this end, several applications using DRAGON2 are presented as well. This new version facilitates the users to include their own physical models by means of a modular C++ structure.« less

KMCLib 1.1: Extended random number support and technical updates to the KMCLib general framework for kinetic Monte-Carlo simulations

NASA Astrophysics Data System (ADS)

Leetmaa, Mikael; Skorodumova, Natalia V.

2015-11-01

We here present a revised version, v1.1, of the KMCLib general framework for kinetic Monte-Carlo (KMC) simulations. The generation of random numbers in KMCLib now relies on the C++11 standard library implementation, and support has been added for the user to choose from a set of C++11 implemented random number generators. The Mersenne-twister, the 24 and 48 bit RANLUX and a 'minimal-standard' PRNG are supported. We have also included the possibility to use true random numbers via the C++11 std::random_device generator. This release also includes technical updates to support the use of an extended range of operating systems and compilers.

Austrian Lipid Consensus on the management of metabolic lipid disorders to prevent vascular complications: A joint position statement issued by eight medical societies. 2016 update.

PubMed

Toplak, Hermann; Ludvik, Bernhard; Lechleitner, Monika; Dieplinger, Hans; Föger, Bernhard; Paulweber, Bernhard; Weber, Thomas; Watschinger, Bruno; Horn, Sabine; Wascher, Thomas C; Drexel, Heinz; Brodmann, Marianne; Pilger, Ernst; Rosenkranz, Alexander; Pohanka, Erich; Oberbauer, Rainer; Traindl, Otto; Roithinger, Franz Xaver; Metzler, Bernhard; Haring, Hans-Peter; Kiechl, Stefan

2016-04-01

In 2010, eight Austrian medical societies proposed a joint position statement on the management of metabolic lipid disorders for the prevention of vascular complications. An updated and extended version of these recommendations according to the current literature is presented, referring to the primary and secondary prevention of vascular complications in adults, taking into consideration the guidelines of other societies. The "Austrian Lipid Consensus - 2016 update" provides guidance for individualized risk stratification and respective therapeutic targets, and discusses the evidence for reducing vascular endpoints with available lipid-lowering therapies. Furthermore, specific management in key patient groups is outlined, including subjects presenting with coronary, cerebrovascular, and/or peripheral atherosclerosis; diabetes mellitus and/or metabolic syndrome; nephropathy; and familial hypercholesterolemia.

Revisiting Southern Hemisphere polar stratospheric temperature trends in WACCM: The role of dynamical forcing

NASA Astrophysics Data System (ADS)

Calvo, N.; Garcia, R. R.; Kinnison, D. E.

2017-04-01

The latest version of the Whole Atmosphere Community Climate Model (WACCM), which includes a new chemistry scheme and an updated parameterization of orographic gravity waves, produces temperature trends in the Antarctic lower stratosphere in excellent agreement with radiosonde observations for 1969-1998 as regards magnitude, location, timing, and persistence. The maximum trend, reached in November at 100 hPa, is -4.4 ± 2.8 K decade-1, which is a third smaller than the largest trend in the previous version of WACCM. Comparison with a simulation without the updated orographic gravity wave parameterization, together with analysis of the model's thermodynamic budget, reveals that the reduced trend is due to the effects of a stronger Brewer-Dobson circulation in the new simulations, which warms the polar cap. The effects are both direct (a trend in adiabatic warming in late spring) and indirect (a smaller trend in ozone, hence a smaller reduction in shortwave heating, due to the warmer environment).

The Nombela 2.0 semantic battery: an updated Spanish instrument for the study of semantic processing.

PubMed

Moreno-Martínez, F Javier; Rodríguez-Rojo, Inmaculada C

2015-01-01

In this study, the Nombela 2.0 semantic battery is presented. This is a new version of its earlier precedent: the battery Nombela (I), in an attempt to improve it (dealing with ceiling effects) and reducing the application time by decreasing the number of tasks. The battery is constructed on a common set of 98 stimuli, including both living and nonliving semantic domains. It consists of five tasks designed to explore category specificity by tapping semantic production and comprehension, using both visual and verbal input. All of the items were rated according to Spanish norms, as stated in a previous study of our group, and all of the tasks were matched across domain on six nuisance variables. The present study has two goals: (i) to make available the updated version (2.0) of the Nombela semantic memory battery and (ii) to characterize and compare the neuropsychological profiles of two different patient groups: mild cognitive impairment and Alzheimer disease, with regard to normal controls.

ROBUS-2: A Fault-Tolerant Broadcast Communication System

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo; Malekpour, Mahyar R.; Miner, Paul S.

2005-01-01

The Reliable Optical Bus (ROBUS) is the core communication system of the Scalable Processor-Independent Design for Enhanced Reliability (SPIDER), a general-purpose fault-tolerant integrated modular architecture currently under development at NASA Langley Research Center. The ROBUS is a time-division multiple access (TDMA) broadcast communication system with medium access control by means of time-indexed communication schedule. ROBUS-2 is a developmental version of the ROBUS providing guaranteed fault-tolerant services to the attached processing elements (PEs), in the presence of a bounded number of faults. These services include message broadcast (Byzantine Agreement), dynamic communication schedule update, clock synchronization, and distributed diagnosis (group membership). The ROBUS also features fault-tolerant startup and restart capabilities. ROBUS-2 is tolerant to internal as well as PE faults, and incorporates a dynamic self-reconfiguration capability driven by the internal diagnostic system. This version of the ROBUS is intended for laboratory experimentation and demonstrations of the capability to reintegrate failed nodes, dynamically update the communication schedule, and tolerate and recover from correlated transient faults.

External RNA Controls Consortium Beta Version Update.

PubMed

Lee, Hangnoh; Pine, P Scott; McDaniel, Jennifer; Salit, Marc; Oliver, Brian

2016-01-01

Spike-in RNAs are valuable controls for a variety of gene expression measurements. The External RNA Controls Consortium developed test sets that were used in a number of published reports. Here we provide an authoritative table that summarizes, updates, and corrects errors in the test version that ultimately resulted in the certified Standard Reference Material 2374. We have noted existence of anti-sense RNA controls in the material, corrected sub-pool memberships, and commented on control RNAs that displayed inconsistent behavior.

A program for calculating photonic band structures, Green's functions and transmission/reflection coefficients using a non-orthogonal FDTD method

NASA Astrophysics Data System (ADS)

Ward, A. J.; Pendry, J. B.

2000-06-01

In this paper we present an updated version of our ONYX program for calculating photonic band structures using a non-orthogonal finite difference time domain method. This new version employs the same transparent formalism as the first version with the same capabilities for calculating photonic band structures or causal Green's functions but also includes extra subroutines for the calculation of transmission and reflection coefficients. Both the electric and magnetic fields are placed onto a discrete lattice by approximating the spacial and temporal derivatives with finite differences. This results in discrete versions of Maxwell's equations which can be used to integrate the fields forwards in time. The time required for a calculation using this method scales linearly with the number of real space points used in the discretization so the technique is ideally suited to handling systems with large and complicated unit cells.

RAID v2.0: an updated resource of RNA-associated interactions across organisms

PubMed Central

Yi, Ying; Zhao, Yue; Li, Chunhua; Zhang, Lin; Huang, Huiying; Li, Yana; Liu, Lanlan; Hou, Ping; Cui, Tianyu; Tan, Puwen; Hu, Yongfei; Zhang, Ting; Huang, Yan; Li, Xiaobo; Yu, Jia; Wang, Dong

2017-01-01

With the development of biotechnologies and computational prediction algorithms, the number of experimental and computational prediction RNA-associated interactions has grown rapidly in recent years. However, diverse RNA-associated interactions are scattered over a wide variety of resources and organisms, whereas a fully comprehensive view of diverse RNA-associated interactions is still not available for any species. Hence, we have updated the RAID database to version 2.0 (RAID v2.0, www.rna-society.org/raid/) by integrating experimental and computational prediction interactions from manually reading literature and other database resources under one common framework. The new developments in RAID v2.0 include (i) over 850-fold RNA-associated interactions, an enhancement compared to the previous version; (ii) numerous resources integrated with experimental or computational prediction evidence for each RNA-associated interaction; (iii) a reliability assessment for each RNA-associated interaction based on an integrative confidence score; and (iv) an increase of species coverage to 60. Consequently, RAID v2.0 recruits more than 5.27 million RNA-associated interactions, including more than 4 million RNA–RNA interactions and more than 1.2 million RNA–protein interactions, referring to nearly 130 000 RNA/protein symbols across 60 species. PMID:27899615

User's guide for mapIMG 3--Map image re-projection software package

USGS Publications Warehouse

Finn, Michael P.; Mattli, David M.

2012-01-01

Version 0.0 (1995), Dan Steinwand, U.S. Geological Survey (USGS)/Earth Resources Observation Systems (EROS) Data Center (EDC)--Version 0.0 was a command line version for UNIX that required four arguments: the input metadata, the output metadata, the input data file, and the output destination path. Version 1.0 (2003), Stephen Posch and Michael P. Finn, USGS/Mid-Continent Mapping Center (MCMC--Version 1.0 added a GUI interface that was built using the Qt library for cross platform development. Version 1.01 (2004), Jason Trent and Michael P. Finn, USGS/MCMC--Version 1.01 suggested bounds for the parameters of each projection. Support was added for larger input files, storage of the last used input and output folders, and for TIFF/ GeoTIFF input images. Version 2.0 (2005), Robert Buehler, Jason Trent, and Michael P. Finn, USGS/National Geospatial Technical Operations Center (NGTOC)--Version 2.0 added Resampling Methods (Mean, Mode, Min, Max, and Sum), updated the GUI design, and added the viewer/pre-viewer. The metadata style was changed to XML and was switched to a new naming convention. Version 3.0 (2009), David Mattli and Michael P. Finn, USGS/Center of Excellence for Geospatial Information Science (CEGIS)--Version 3.0 brings optimized resampling methods, an updated GUI, support for less than global datasets, UTM support and the whole codebase was ported to Qt4.

TA-13: Ground and Launch Systems, 2015 NASA Technology Roadmaps

NASA Technical Reports Server (NTRS)

Fox, Jack J.

2015-01-01

This presentation is a summary of new content contained in the 2015 update of Technology Area-13, Ground and Launch Systems technology roadmap beyond the content contained in the 2010 version. Also included are brief assessments of benefits, alignments, challenges, technical risk and reasonableness, sequencing and timing, and time and effort to achieve goals. This presentation is part of overall presentations of new content only for the 2015 update of the 15 NASA Technology Roadmaps that will be conducted in a public forum managed by the National Research Council on September 28-29, 2015. The 15 roadmaps have already been publically released via the STI process.

rSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks.

PubMed

Guo, Liyuan; Wang, Jing

2018-01-04

Here, we present the updated rSNPBase 3.0 database (http://rsnp3.psych.ac.cn), which provides human SNP-related regulatory elements, element-gene pairs and SNP-based regulatory networks. This database is the updated version of the SNP regulatory annotation database rSNPBase and rVarBase. In comparison to the last two versions, there are both structural and data adjustments in rSNPBase 3.0: (i) The most significant new feature is the expansion of analysis scope from SNP-related regulatory elements to include regulatory element-target gene pairs (E-G pairs), therefore it can provide SNP-based gene regulatory networks. (ii) Web function was modified according to data content and a new network search module is provided in the rSNPBase 3.0 in addition to the previous regulatory SNP (rSNP) search module. The two search modules support data query for detailed information (related-elements, element-gene pairs, and other extended annotations) on specific SNPs and SNP-related graphic networks constructed by interacting transcription factors (TFs), miRNAs and genes. (3) The type of regulatory elements was modified and enriched. To our best knowledge, the updated rSNPBase 3.0 is the first data tool supports SNP functional analysis from a regulatory network prospective, it will provide both a comprehensive understanding and concrete guidance for SNP-related regulatory studies. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

rSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks

PubMed Central

2018-01-01

Abstract Here, we present the updated rSNPBase 3.0 database (http://rsnp3.psych.ac.cn), which provides human SNP-related regulatory elements, element-gene pairs and SNP-based regulatory networks. This database is the updated version of the SNP regulatory annotation database rSNPBase and rVarBase. In comparison to the last two versions, there are both structural and data adjustments in rSNPBase 3.0: (i) The most significant new feature is the expansion of analysis scope from SNP-related regulatory elements to include regulatory element–target gene pairs (E–G pairs), therefore it can provide SNP-based gene regulatory networks. (ii) Web function was modified according to data content and a new network search module is provided in the rSNPBase 3.0 in addition to the previous regulatory SNP (rSNP) search module. The two search modules support data query for detailed information (related-elements, element-gene pairs, and other extended annotations) on specific SNPs and SNP-related graphic networks constructed by interacting transcription factors (TFs), miRNAs and genes. (3) The type of regulatory elements was modified and enriched. To our best knowledge, the updated rSNPBase 3.0 is the first data tool supports SNP functional analysis from a regulatory network prospective, it will provide both a comprehensive understanding and concrete guidance for SNP-related regulatory studies. PMID:29140525

ZCURVE 3.0: identify prokaryotic genes with higher accuracy as well as automatically and accurately select essential genes

PubMed Central

Hua, Zhi-Gang; Lin, Yan; Yuan, Ya-Zhou; Yang, De-Chang; Wei, Wen; Guo, Feng-Biao

2015-01-01

In 2003, we developed an ab initio program, ZCURVE 1.0, to find genes in bacterial and archaeal genomes. In this work, we present the updated version (i.e. ZCURVE 3.0). Using 422 prokaryotic genomes, the average accuracy was 93.7% with the updated version, compared with 88.7% with the original version. Such results also demonstrate that ZCURVE 3.0 is comparable with Glimmer 3.02 and may provide complementary predictions to it. In fact, the joint application of the two programs generated better results by correctly finding more annotated genes while also containing fewer false-positive predictions. As the exclusive function, ZCURVE 3.0 contains one post-processing program that can identify essential genes with high accuracy (generally >90%). We hope ZCURVE 3.0 will receive wide use with the web-based running mode. The updated ZCURVE can be freely accessed from http://cefg.uestc.edu.cn/zcurve/ or http://tubic.tju.edu.cn/zcurveb/ without any restrictions. PMID:25977299

Wild Fire Emissions for the NOAA Operational HYSPLIT Smoke Model

NASA Astrophysics Data System (ADS)

Huang, H. C.; ONeill, S. M.; Ruminski, M.; Shafran, P.; McQueen, J.; DiMego, G.; Kondragunta, S.; Gorline, J.; Huang, J. P.; Stunder, B.; Stein, A. F.; Stajner, I.; Upadhayay, S.; Larkin, N. K.

2015-12-01

Particulate Matter (PM) generated from forest fires often lead to degraded visibility and unhealthy air quality in nearby and downstream areas. To provide near-real time PM information to the state and local agencies, the NOAA/National Weather Service (NWS) operational HYSPLIT (Hybrid Single Particle Lagrangian Integrated Trajectory Model) smoke modeling system (NWS/HYSPLIT smoke) provides the forecast of smoke concentration resulting from fire emissions driven by the NWS North American Model 12 km weather predictions. The NWS/HYSPLIT smoke incorporates the U.S. Forest Service BlueSky Smoke Modeling Framework (BlueSky) to provide smoke fire emissions along with the input fire locations from the NOAA National Environmental Satellite, Data, and Information Service (NESDIS)'s Hazard Mapping System fire and smoke detection system. Experienced analysts inspect satellite imagery from multiple sensors onboard geostationary and orbital satellites to identify the location, size and duration of smoke emissions for the model. NWS/HYSPLIT smoke is being updated to use a newer version of USFS BlueSky. The updated BlueSky incorporates the Fuel Characteristic Classification System version 2 (FCCS2) over the continental U.S. and Alaska. FCCS2 includes a more detailed description of fuel loadings with additional plant type categories. The updated BlueSky also utilizes an improved fuel consumption model and fire emission production system. For the period of August 2014 and June 2015, NWS/HYSPLIT smoke simulations show that fire smoke emissions with updated BlueSky are stronger than the current operational BlueSky in the Northwest U.S. For the same comparisons, weaker fire smoke emissions from the updated BlueSky were observed over the middle and eastern part of the U.S. A statistical evaluation of NWS/HYSPLIT smoke predicted total column concentration compared to NOAA NESDIS GOES EAST Aerosol Smoke Product retrievals is underway. Preliminary results show that using the newer version of BlueSky leads to improved performance of NWS/HYSPLIT-smoke for June 2015. These results are partially due to the default fuel loading selected for Canadian fires that lead to stronger fire emissions there. The use of more realistic Canadian fuel loading may improve NWS/HYSPLIT smoke forecast.

Rare Earth Element Concentration of Wyoming Thermal Waters Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quillinan, Scott; Nye, Charles; Neupane, Hari

Updated version of data generated from rare earth element investigation of produced waters. These data represent major, minor, trace, isotopes, and rare earth element concentrations in geologic formations and water associated with oil and gas production.

UCbase 2.0: ultraconserved sequences database (2014 update).

PubMed

Lomonaco, Vincenzo; Martoglia, Riccardo; Mandreoli, Federica; Anderlucci, Laura; Emmett, Warren; Bicciato, Silvio; Taccioli, Cristian

2014-01-01

UCbase 2.0 (http://ucbase.unimore.it) is an update, extension and evolution of UCbase, a Web tool dedicated to the analysis of ultraconserved sequences (UCRs). UCRs are 481 sequences >200 bases sharing 100% identity among human, mouse and rat genomes. They are frequently located in genomic regions known to be involved in cancer or differentially expressed in human leukemias and carcinomas. UCbase 2.0 is a platform-independent Web resource that includes the updated version of the human genome annotation (hg19), information linking disorders to chromosomal coordinates based on the Systematized Nomenclature of Medicine classification, a query tool to search for Single Nucleotide Polymorphisms (SNPs) and a new text box to directly interrogate the database using a MySQL interface. To facilitate the interactive visual interpretation of UCR chromosomal positioning, UCbase 2.0 now includes a graph visualization interface directly linked to UCSC genome browser. Database URL: http://ucbase.unimore.it. © The Author(s) 2014. Published by Oxford University Press.

Update on Development of Mesh Generation Algorithms in MeshKit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, Rajeev; Vanderzee, Evan; Mahadevan, Vijay

2015-09-30

MeshKit uses a graph-based design for coding all its meshing algorithms, which includes the Reactor Geometry (and mesh) Generation (RGG) algorithms. This report highlights the developmental updates of all the algorithms, results and future work. Parallel versions of algorithms, documentation and performance results are reported. RGG GUI design was updated to incorporate new features requested by the users; boundary layer generation and parallel RGG support were added to the GUI. Key contributions to the release, upgrade and maintenance of other SIGMA1 libraries (CGM and MOAB) were made. Several fundamental meshing algorithms for creating a robust parallel meshing pipeline in MeshKitmore » are under development. Results and current status of automated, open-source and high quality nuclear reactor assembly mesh generation algorithms such as trimesher, quadmesher, interval matching and multi-sweeper are reported.« less

Assembly: a resource for assembled genomes at NCBI

PubMed Central

Kitts, Paul A.; Church, Deanna M.; Thibaud-Nissen, Françoise; Choi, Jinna; Hem, Vichet; Sapojnikov, Victor; Smith, Robert G.; Tatusova, Tatiana; Xiang, Charlie; Zherikov, Andrey; DiCuccio, Michael; Murphy, Terence D.; Pruitt, Kim D.; Kimchi, Avi

2016-01-01

The NCBI Assembly database (www.ncbi.nlm.nih.gov/assembly/) provides stable accessioning and data tracking for genome assembly data. The model underlying the database can accommodate a range of assembly structures, including sets of unordered contig or scaffold sequences, bacterial genomes consisting of a single complete chromosome, or complex structures such as a human genome with modeled allelic variation. The database provides an assembly accession and version to unambiguously identify the set of sequences that make up a particular version of an assembly, and tracks changes to updated genome assemblies. The Assembly database reports metadata such as assembly names, simple statistical reports of the assembly (number of contigs and scaffolds, contiguity metrics such as contig N50, total sequence length and total gap length) as well as the assembly update history. The Assembly database also tracks the relationship between an assembly submitted to the International Nucleotide Sequence Database Consortium (INSDC) and the assembly represented in the NCBI RefSeq project. Users can find assemblies of interest by querying the Assembly Resource directly or by browsing available assemblies for a particular organism. Links in the Assembly Resource allow users to easily download sequence and annotations for current versions of genome assemblies from the NCBI genomes FTP site. PMID:26578580

CRISPRCasFinder, an update of CRISRFinder, includes a portable version, enhanced performance and integrates search for Cas proteins.

PubMed

Couvin, David; Bernheim, Aude; Toffano-Nioche, Claire; Touchon, Marie; Michalik, Juraj; Néron, Bertrand; C Rocha, Eduardo P; Vergnaud, Gilles; Gautheret, Daniel; Pourcel, Christine

2018-05-22

CRISPR (clustered regularly interspaced short palindromic repeats) arrays and their associated (Cas) proteins confer bacteria and archaea adaptive immunity against exogenous mobile genetic elements, such as phages or plasmids. CRISPRCasFinder allows the identification of both CRISPR arrays and Cas proteins. The program includes: (i) an improved CRISPR array detection tool facilitating expert validation based on a rating system, (ii) prediction of CRISPR orientation and (iii) a Cas protein detection and typing tool updated to match the latest classification scheme of these systems. CRISPRCasFinder can either be used online or as a standalone tool compatible with Linux operating system. All third-party software packages employed by the program are freely available. CRISPRCasFinder is available at https://crisprcas.i2bc.paris-saclay.fr.

NONCODE v2.0: decoding the non-coding.

PubMed

He, Shunmin; Liu, Changning; Skogerbø, Geir; Zhao, Haitao; Wang, Jie; Liu, Tao; Bai, Baoyan; Zhao, Yi; Chen, Runsheng

2008-01-01

The NONCODE database is an integrated knowledge database designed for the analysis of non-coding RNAs (ncRNAs). Since NONCODE was first released 3 years ago, the number of known ncRNAs has grown rapidly, and there is growing recognition that ncRNAs play important regulatory roles in most organisms. In the updated version of NONCODE (NONCODE v2.0), the number of collected ncRNAs has reached 206 226, including a wide range of microRNAs, Piwi-interacting RNAs and mRNA-like ncRNAs. The improvements brought to the database include not only new and updated ncRNA data sets, but also an incorporation of BLAST alignment search service and access through our custom UCSC Genome Browser. NONCODE can be found under http://www.noncode.org or http://noncode.bioinfo.org.cn.

Covariance Data File Formats for Whisper-1.0 & Whisper-1.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Forrest B.; Rising, Michael Evan

2017-01-09

Whisper is a statistical analysis package developed in 2014 to support nuclear criticality safety (NCS) validation. It uses the sensitivity profile data for an application as computed by MCNP6 along with covariance files for the nuclear data to determine a baseline upper-subcritical-limit (USL) for the application. Whisper version 1.0 was first developed and used at LANL in 2014. During 2015-2016, Whisper was updated to version 1.1 and is to be included with the upcoming release of MCNP6.2. This report describes the file formats used for the covariance data in both Whisper-1.0 and Whisper-1.1.

Proposal for an Update of the Definition and Scope of Behavioral Medicine.

PubMed

Dekker, Joost; Stauder, Adrienne; Penedo, Frank J

2017-02-01

We aim to provide an update of the definition and scope of behavioral medicine in the Charter of ISBM, as the present version was developed more than 25 years ago. We identify issues which need clarification or updating. This leads us to propose an update of the definition and scope of behavioral medicine. Issues in need of clarification or updating include the scope of behavioral medicine (biobehavioral mechanisms, clinical diagnosis and intervention, and prevention and health promotion); research as an essential characteristic of all three areas of behavioral medicine; the application of behavioral medicine; the terminology of behavioral medicine as a multidisciplinary field; and the relationship and distinction between behavioral medicine, mental health, health psychology, and psychosomatic medicine. We propose the following updated definition and scope of behavioral medicine: "Behavioral medicine can be defined as the multidisciplinary field concerned with the development and integration of biomedical and behavioral knowledge relevant to health and disease, and the application of this knowledge to prevention, health promotion, diagnosis, treatment, rehabilitation, and care. The scope of behavioral medicine extends from biobehavioral mechanisms (i.e., the interaction of biomedical processes with psychological, social, societal, cultural, and environmental processes), to clinical diagnosis and intervention, and to public health."

[Guideline for the Diagnosis and Treatment of Asthma - Guideline of the German Respiratory Society and the German Atemwegsliga in Cooperation with the Paediatric Respiratory Society and the Austrian Society of Pneumology].

PubMed

Buhl, R; Bals, R; Baur, X; Berdel, D; Criée, C-P; Gappa, M; Gillissen, A; Greulich, T; Haidl, P; Hamelmann, E; Kardos, P; Kenn, K; Klimek, L; Korn, S; Lommatzsch, M; Magnussen, H; Nicolai, T; Nowak, D; Pfaar, O; Rabe, K F; Riedler, J; Ritz, T; Schultz, K; Schuster, A; Spindler, T; Taube, C; Taube, K; Vogelmeier, C; von Leupold, A; Wantke, F; Weise, S; Wildhaber, J; Worth, H; Zacharasiewicz, A

2017-12-01

The present guideline is a new version and an update of the guideline for the diagnosis and treatment of asthma, which replaces the previous version for german speaking countries from the year 2006. The wealth of new data on the pathophysiology and the phenotypes of asthma, and the expanded spectrum of diagnostic and therapeutic options necessitated a new version and an update. This guideline presents the current, evidence-based recommendations for the diagnosis and treatment of asthma, for children and adolescents as well as for adults with asthma. © Georg Thieme Verlag KG Stuttgart · New York.

New version of 1 km global river flood hazard maps for the next generation of Aqueduct Global Flood Analyzer

NASA Astrophysics Data System (ADS)

Sutanudjaja, Edwin; van Beek, Rens; Winsemius, Hessel; Ward, Philip; Bierkens, Marc

2017-04-01

The Aqueduct Global Flood Analyzer, launched in 2015, is an open-access and free-of-charge web-based interactive platform which assesses and visualises current and future projections of river flood impacts across the globe. One of the key components in the Analyzer is a set of river flood inundation hazard maps derived from the global hydrological model simulation of PCR-GLOBWB. For the current version of the Analyzer, accessible on http://floods.wri.org/#/, the early generation of PCR-GLOBWB 1.0 was used and simulated at 30 arc-minute ( 50 km at the equator) resolution. In this presentation, we will show the new version of these hazard maps. This new version is based on the latest version of PCR-GLOBWB 2.0 (https://github.com/UU-Hydro/PCR-GLOBWB_model, Sutanudjaja et al., 2016, doi:10.5281/zenodo.60764) simulated at 5 arc-minute ( 10 km at the equator) resolution. The model simulates daily hydrological and water resource fluxes and storages, including the simulation of overbank volume that ends up on the floodplain (if flooding occurs). The simulation was performed for the present day situation (from 1960) and future climate projections (until 2099) using the climate forcing created in the ISI-MIP project. From the simulated flood inundation volume time series, we then extract annual maxima for each cell, and fit these maxima to a Gumbel extreme value distribution. This allows us to derive flood volume maps of any hazard magnitude (ranging from 2-year to 1000-year flood events) and for any time period (e.g. 1960-1999, 2010-2049, 2030-2069, and 2060-2099). The derived flood volumes (at 5 arc-minute resolution) are then spread over the high resolution terrain model using an updated GLOFRIS downscaling module (Winsemius et al., 2013, doi:10.5194/hess-17-1871-2013). The updated version performs a volume spreading sequentially from more upstream basins to downstream basins, hence enabling a better inclusion of smaller streams, and takes into account spreading of water over diverging deltaic regions. This results in a set of high resolution hazard maps of flood inundation depth at 30 arc-second ( 1 km at the equator) resolution. Together with many other updates and new features, the resulting flood hazard maps will be used in the next generation of the Aqueduct Global Flood Analyzer.

The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection.

PubMed

Fernández-Suárez, Xosé M; Rigden, Daniel J; Galperin, Michael Y

2014-01-01

The 2014 Nucleic Acids Research Database Issue includes descriptions of 58 new molecular biology databases and recent updates to 123 databases previously featured in NAR or other journals. For convenience, the issue is now divided into eight sections that reflect major subject categories. Among the highlights of this issue are six databases of the transcription factor binding sites in various organisms and updates on such popular databases as CAZy, Database of Genomic Variants (DGV), dbGaP, DrugBank, KEGG, miRBase, Pfam, Reactome, SEED, TCDB and UniProt. There is a strong block of structural databases, which includes, among others, the new RNA Bricks database, updates on PDBe, PDBsum, ArchDB, Gene3D, ModBase, Nucleic Acid Database and the recently revived iPfam database. An update on the NCBI's MMDB describes VAST+, an improved tool for protein structure comparison. Two articles highlight the development of the Structural Classification of Proteins (SCOP) database: one describes SCOPe, which automates assignment of new structures to the existing SCOP hierarchy; the other one describes the first version of SCOP2, with its more flexible approach to classifying protein structures. This issue also includes a collection of articles on bacterial taxonomy and metagenomics, which includes updates on the List of Prokaryotic Names with Standing in Nomenclature (LPSN), Ribosomal Database Project (RDP), the Silva/LTP project and several new metagenomics resources. The NAR online Molecular Biology Database Collection, http://www.oxfordjournals.org/nar/database/c/, has been expanded to 1552 databases. The entire Database Issue is freely available online on the Nucleic Acids Research website (http://nar.oxfordjournals.org/).

The digital geologic map of Colorado in ARC/INFO format, Part A. Documentation

USGS Publications Warehouse

Green, Gregory N.

1992-01-01

This geologic map was prepared as a part of a study of digital methods and techniques as applied to complex geologic maps. The geologic map was digitized from the original scribe sheets used to prepare the published Geologic Map of Colorado (Tweto 1979). Consequently the digital version is at 1:500,000 scale using the Lambert Conformal Conic map projection parameters of the state base map. Stable base contact prints of the scribe sheets were scanned on a Tektronix 4991 digital scanner. The scanner automatically converts the scanned image to an ASCII vector format. These vectors were transferred to a VAX minicomputer, where they were then loaded into ARC/INFO. Each vector and polygon was given attributes derived from the original 1979 geologic map. This database was developed on a MicroVAX computer system using VAX V 5.4 nd ARC/INFO 5.0 software. UPDATE: April 1995, The update was done solely for the purpose of adding the abilitly to plot to an HP650c plotter. Two new ARC/INFO plot AMLs along with a lineset and shadeset for the HP650C design jet printer have been included. These new files are COLORADO.650, INDEX.650, TWETOLIN.E00 and TWETOSHD.E00. These files were created on a UNIX platform with ARC/INFO 6.1.2. Updated versions of INDEX.E00, CONTACT.E00, LINE.E00, DECO.E00 and BORDER.E00 files that included the newly defined HP650c items are also included. * Any use of trade, product, or firm names is for descriptive purposes only and does not imply endorsement by the U.S. Government. Descriptors: The Digital Geologic Map of Colorado in ARC/INFO Format Open-File Report 92-050

The digital geologic map of Colorado in ARC/INFO format, Part B. Common files

USGS Publications Warehouse

Green, Gregory N.

1992-01-01

This geologic map was prepared as a part of a study of digital methods and techniques as applied to complex geologic maps. The geologic map was digitized from the original scribe sheets used to prepare the published Geologic Map of Colorado (Tweto 1979). Consequently the digital version is at 1:500,000 scale using the Lambert Conformal Conic map projection parameters of the state base map. Stable base contact prints of the scribe sheets were scanned on a Tektronix 4991 digital scanner. The scanner automatically converts the scanned image to an ASCII vector format. These vectors were transferred to a VAX minicomputer, where they were then loaded into ARC/INFO. Each vector and polygon was given attributes derived from the original 1979 geologic map. This database was developed on a MicroVAX computer system using VAX V 5.4 nd ARC/INFO 5.0 software. UPDATE: April 1995, The update was done solely for the purpose of adding the abilitly to plot to an HP650c plotter. Two new ARC/INFO plot AMLs along with a lineset and shadeset for the HP650C design jet printer have been included. These new files are COLORADO.650, INDEX.650, TWETOLIN.E00 and TWETOSHD.E00. These files were created on a UNIX platform with ARC/INFO 6.1.2. Updated versions of INDEX.E00, CONTACT.E00, LINE.E00, DECO.E00 and BORDER.E00 files that included the newly defined HP650c items are also included. * Any use of trade, product, or firm names is for descriptive purposes only and does not imply endorsement by the U.S. Government. Descriptors: The Digital Geologic Map of Colorado in ARC/INFO Format Open-File Report 92-050

The Influence of Computers and Informatics on Mathematics and Its Teaching. Science and Technology Education Series, 44.

ERIC Educational Resources Information Center

Cornu, Bernard, Ed.; Ralston, Anthony, Ed.

In 1985 the International Commission on Mathematical Instruction (ICMI) published the first edition of a book of studies on the topic of the influence of computers on mathematics and the teaching of mathematics. This document is an updated version of that book and includes five articles from the 1985 ICMI conference at Strasbourg, France; reports…

Southern Horticultural Lab Update

USDA-ARS?s Scientific Manuscript database

This publication is a new quarterly update for members of the Mississippi Nursery and Landscape Association that is published quarterly in their association newsletter. Two other versions of this newsletter are being submitted to the Louisiana Nursery and Landscape Association (LALNLA) and the Alaba...

OMI Global Tropospheric Bromine Oxide (BrO) Column Densities: Algorithm, Retrieval and Initial Validation

NASA Astrophysics Data System (ADS)

Suleiman, R. M.; Chance, K.; Liu, X.; Kurosu, T. P.; Gonzalez Abad, G.

2014-12-01

We present and discuss a detailed description of the retrieval algorithms for the OMI BrO product. The BrO algorithms are based on direct fitting of radiances from 319.0-347.5 nm. Radiances are modeled from the solar irradiance, attenuated and adjusted by contributions from the target gas and interfering gases, rotational Raman scattering, undersampling, additive and multiplicative closure polynomials and a common mode spectrum. The version of the algorithm used for both BrO includes relevant changes with respect to the operational code, including the fit of the O2-O2 collisional complex, updates in the high resolution solar reference spectrum, updates in spectroscopy, an updated Air Mass Factor (AMF) calculation scheme, and the inclusion of scattering weights and vertical profiles in the level 2 products. Updates to the algorithms include accurate scattering weights and air mass factor calculations, scattering weights and profiles in outputs and available cross sections. We include retrieval parameter and window optimization to reduce the interference from O3, HCHO, O2-O2, SO2, improve fitting accuracy and uncertainty, reduce striping, and improve the long-term stability. We validate OMI BrO with ground-based measurements from Harestua and with chemical transport model simulations. We analyze the global distribution and seasonal variation of BrO and investigate BrO emissions from volcanoes and salt lakes.

BehavePlus fire modeling system, version 5.0: Variables

Treesearch

Patricia L. Andrews

2009-01-01

This publication has been revised to reflect updates to version 4.0 of the BehavePlus software. It was originally published as the BehavePlus fire modeling system, version 4.0: Variables in July, 2008.The BehavePlus fire modeling system is a computer program based on mathematical models that describe wildland fire behavior and effects and the...

Source Update Capture in Information Agents

NASA Technical Reports Server (NTRS)

Ashish, Naveen; Kulkarni, Deepak; Wang, Yao

2003-01-01

In this paper we present strategies for successfully capturing updates at Web sources. Web-based information agents provide integrated access to autonomous Web sources that can get updated. For many information agent applications we are interested in knowing when a Web source to which the application provides access, has been updated. We may also be interested in capturing all the updates at a Web source over a period of time i.e., detecting the updates and, for each update retrieving and storing the new version of data. Previous work on update and change detection by polling does not adequately address this problem. We present strategies for intelligently polling a Web source for efficiently capturing changes at the source.

International Spinal Cord Injury Core Data Set (version 2.0)-including standardization of reporting.

PubMed

Biering-Sørensen, F; DeVivo, M J; Charlifue, S; Chen, Y; New, P W; Noonan, V; Post, M W M; Vogel, L

2017-08-01

The study design includes expert opinion, feedback, revisions and final consensus. The objective of the study was to present the new knowledge obtained since the International Spinal Cord Injury (SCI) Core Data Set (Version 1.0) published in 2006, and describe the adjustments made in Version 2.0, including standardization of data reporting. International. Comments received from the SCI community were discussed in a working group (WG); suggestions from the WG were reviewed and revisions were made. All suggested revisions were considered, and a final version was circulated for final approval. The International SCI Core Data Set (Version 2.0) consists of 25 variables. Changes made to this version include the deletion of one variable 'Total Days Hospitalized' and addition of two variables 'Date of Rehabilitation Admission' and 'Date of Death.' The variable 'Injury Etiology' was extended with six non-traumatic categories, and corresponding 'Date of Injury' for non-traumatic cases, was defined as the date of first physician visit for symptoms related to spinal cord dysfunction. A category reflecting transgender was added. A response category was added to the variable on utilization of ventilatory assistance to document the use of continuous positive airway pressure for sleep apnea. Other clarifications were made to the text. The reporting of the pediatric SCI population was updated as age groups 0-5, 6-12, 13-14, 15-17 and 18-21. Collection of the core data set should be a basic requirement of all studies of SCI to facilitate accurate descriptions of patient populations and comparison of results across published studies from around the world.

Modelling the climate and surface mass balance of polar ice sheets using RACMO2 - Part 1: Greenland (1958-2016)

NASA Astrophysics Data System (ADS)

Noël, Brice; van de Berg, Willem Jan; Melchior van Wessem, J.; van Meijgaard, Erik; van As, Dirk; Lenaerts, Jan T. M.; Lhermitte, Stef; Kuipers Munneke, Peter; Smeets, C. J. P. Paul; van Ulft, Lambertus H.; van de Wal, Roderik S. W.; van den Broeke, Michiel R.

2018-03-01

We evaluate modelled Greenland ice sheet (GrIS) near-surface climate, surface energy balance (SEB) and surface mass balance (SMB) from the updated regional climate model RACMO2 (1958-2016). The new model version, referred to as RACMO2.3p2, incorporates updated glacier outlines, topography and ice albedo fields. Parameters in the cloud scheme governing the conversion of cloud condensate into precipitation have been tuned to correct inland snowfall underestimation: snow properties are modified to reduce drifting snow and melt production in the ice sheet percolation zone. The ice albedo prescribed in the updated model is lower at the ice sheet margins, increasing ice melt locally. RACMO2.3p2 shows good agreement compared to in situ meteorological data and point SEB/SMB measurements, and better resolves the spatial patterns and temporal variability of SMB compared with the previous model version, notably in the north-east, south-east and along the K-transect in south-western Greenland. This new model version provides updated, high-resolution gridded fields of the GrIS present-day climate and SMB, and will be used for projections of the GrIS climate and SMB in response to a future climate scenario in a forthcoming study.

The Biomolecular Crystallization Database Version 4: expanded content and new features.

PubMed

Tung, Michael; Gallagher, D Travis

2009-01-01

The Biological Macromolecular Crystallization Database (BMCD) has been a publicly available resource since 1988, providing a curated archive of information on crystal growth for proteins and other biological macromolecules. The BMCD content has recently been expanded to include 14 372 crystal entries. The resource continues to be freely available at http://xpdb.nist.gov:8060/BMCD4. In addition, the software has been adapted to support the Java-based Lucene query language, enabling detailed searching over specific parameters, and explicit search of parameter ranges is offered for five numeric variables. Extensive tools have been developed for import and handling of data from the RCSB Protein Data Bank. The updated BMCD is called version 4.02 or BMCD4. BMCD4 entries have been expanded to include macromolecule sequence, enabling more elaborate analysis of relations among protein properties, crystal-growth conditions and the geometric and diffraction properties of the crystals. The BMCD version 4.02 contains greatly expanded content and enhanced search capabilities to facilitate scientific analysis and design of crystal-growth strategies.

Time Series Analysis of Photovoltaic Soiling Station Data: Version 1.0, August 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Micheli, Leonardo; Muller, Matthew T.; Deceglie, Michael G.

The time series data from PV soiling stations, operating in the USA, at different time periods are analyzed and presented. The current version of the paper includes twenty stations operating between 2013 and 2016, but the paper is intended to be periodically updated as more stations and more data become available. The challenges in working with soiling stations data are discussed, including measurement methodology, quality controls, and measurement uncertainty. The soiling profiles of the soiling stations are made available so that the PV community can make use of this data to guide operations and maintence decisions, estimate soiling derate inmore » performance models, and more generally come to a better understanding of the challenges associated with the variability of PV soiling.« less

The AMCP Format for Formulary Submissions: Welcome to Version 4.0.

PubMed

2016-05-01

Managed care pharmacists are increasingly presented with complex considerations related to prescription drug formulary management. As prescription drug spending soars, and new effective, but expensive drugs rush to the market, pharmacists and other health care decision makers must evaluate a myriad of important clinical and economic considerations in determining the relative value and, subsequently, the appropriate placement of a product within a formulary. The AMCP Format for Formulary Submissions, Version 4.0, is the next iteration of the Format, which was first released in 2000. Version 4.0, developed by pharmacists from health plan, manufacturer, and academic perspectives, provides updated recommendations on acquiring and evaluating clinical and economic evidence to inform formulary and medical policy decisions. It also includes new guidance related to emerging special topic considerations such as biosimilars, specialty pharmacy products, and companion diagnostic tests. Version 4.0 has been modified to improve the usability of the Format, with clarifying guidance related to logistical considerations such as a recommended time frame for implementation of Version 4.0, as well as dossier updates and ongoing communication between manufacturers and health care decision makers. The Format should be used as a framework for ongoing evidence-based dialogue between manufacturers and payers. The evolving health care landscape will require new levels of collaboration and communication among key stakeholders to successfully navigate the challenges of this new environment. The Format provides a framework to support these critical interactions related to product value by facilitating an evidence-based, transparent approach. This document was prepared by Jeff Lee, PharmD, FCCP, on behalf of the AMCP Format Executive Committee. Committee members reviewed and provided feedback on the final draft. No conflicts of interest, financial or otherwise, were reported.

Getting it right from birth to kindergarten: what's new in the Rourke Baby Record?

PubMed

Rourke, Leslie; Leduc, Denis; Constantin, Evelyn; Carsley, Sarah; Rourke, James; Li, Patricia

2013-04-01

To provide an overview of the 2011 edition of the Rourke Baby Record (RBR), which includes developments on its website and new related initiatives that incorporate recent literature on preventive health care for children aged 0 to 5 years. As in past RBR editions, recommendations are identified as supported by good, fair, or consensus evidence, according to the classifications adopted by the Canadian Task Force on Preventive Health Care in 2011. New information and recommendations are given for growth monitoring, nutrition, physical examination maneuvers, and immunizations for varicella, pneumococcus, meningococcus, and rotavirus. There is now good evidence for converting to the World Health Organization growth charts adapted for Canada, universal newborn hearing screening, and use of immunization pain reduction strategies. Anticipatory guidance has been updated for safe sleeping, health supervision of foster children, fetal alcohol spectrum disorder, lead and anemia screening risk factors, and dental care and oral health. New RBR website items include a parent resources section, modifications for unique populations such as those living in Nunavut, a version of the RBR that highlights what has changed from the 2009 version for quick viewing, and an expansion of the "Explore the RBR" feature with associated links to relevant information. A one-visit-per-page format is now available. The 2011 RBR is endorsed by the College of Family Physicians of Canada and the Canadian Paediatric Society, and is available in English and French in national and Ontario versions. The 2011 RBR is an updated, evidence-based, practical knowledge translation tool for preventive health care for infants from birth to age 5 years that includes extensive Web-based resources for health care professionals, students, residents, and parents.

Human Visuospatial Updating After Passive Translations In Three-Dimensional Space

PubMed Central

Klier, Eliana M.; Hess, Bernhard J. M.; Angelaki, Dora E.

2013-01-01

To maintain a stable representation of the visual environment as we move, the brain must update the locations of targets in space using extra-retinal signals. Humans can accurately update after intervening active whole-body translations. But can they also update for passive translations (i.e., without efference copy signals of an outgoing motor command)? We asked six head-fixed subjects to remember the location of a briefly flashed target (five possible targets were located at depths of 23, 33, 43, 63 and 150cm in front of the cyclopean eye) as they moved 10cm left, right, up, down, forward or backward, while fixating a head-fixed target at 53cm. After the movement, the subjects made a saccade to the remembered location of the flash with a combination of version and vergence eye movements. We computed an updating ratio where 0 indicates no updating and 1 indicates perfect updating. For lateral and vertical whole-body motion, where updating performance is judged by the size of the version movement, the updating ratios were similar for leftward and rightward translations, averaging 0.84±0.28 (mean±SD), as compared to 0.51±0.33 for downward and 1.05±0.50 for upward translations. For forward/backward movements, where updating performance is judged by the size of the vergence movement, the average updating ratio was 1.12±0.45. Updating ratios tended to be larger for far targets than near targets, although both intra- and inter-subject variabilities were smallest for near targets. Thus, in addition to self-generated movements, extra-retinal signals involving otolith and proprioceptive cues can also be used for spatial constancy. PMID:18256164

Computer virus information update CIAC-2301

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orvis, W.J.

1994-01-15

While CIAC periodically issues bulletins about specific computer viruses, these bulletins do not cover all the computer viruses that affect desktop computers. The purpose of this document is to identify most of the known viruses for the MS-DOS and Macintosh platforms and give an overview of the effects of each virus. The authors also include information on some windows, Atari, and Amiga viruses. This document is revised periodically as new virus information becomes available. This document replaces all earlier versions of the CIAC Computer virus Information Update. The date on the front cover indicates date on which the information inmore » this document was extracted from CIAC`s Virus database.« less

ZCURVE 3.0: identify prokaryotic genes with higher accuracy as well as automatically and accurately select essential genes.

PubMed

Hua, Zhi-Gang; Lin, Yan; Yuan, Ya-Zhou; Yang, De-Chang; Wei, Wen; Guo, Feng-Biao

2015-07-01

In 2003, we developed an ab initio program, ZCURVE 1.0, to find genes in bacterial and archaeal genomes. In this work, we present the updated version (i.e. ZCURVE 3.0). Using 422 prokaryotic genomes, the average accuracy was 93.7% with the updated version, compared with 88.7% with the original version. Such results also demonstrate that ZCURVE 3.0 is comparable with Glimmer 3.02 and may provide complementary predictions to it. In fact, the joint application of the two programs generated better results by correctly finding more annotated genes while also containing fewer false-positive predictions. As the exclusive function, ZCURVE 3.0 contains one post-processing program that can identify essential genes with high accuracy (generally >90%). We hope ZCURVE 3.0 will receive wide use with the web-based running mode. The updated ZCURVE can be freely accessed from http://cefg.uestc.edu.cn/zcurve/ or http://tubic.tju.edu.cn/zcurveb/ without any restrictions. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Primary Immunodeficiency Diseases: An Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency

PubMed Central

Al-Herz, Waleed; Bousfiha, Aziz; Casanova, Jean-Laurent; Chapel, Helen; Conley, Mary Ellen; Cunningham-Rundles, Charlotte; Etzioni, Amos; Fischer, Alain; Franco, Jose Luis; Geha, Raif S.; Hammarström, Lennart; Nonoyama, Shigeaki; Notarangelo, Luigi Daniele; Ochs, Hans Dieter; Puck, Jennifer M.; Roifman, Chaim M.; Seger, Reinhard; Tang, Mimi L. K.

2011-01-01

We report the updated classification of primary immunodeficiency diseases, compiled by the ad hoc Expert Committee of the International Union of Immunological Societies. As compared to the previous edition, more than 15 novel disease entities have been added in the updated version. For each disorders, the key clinical and laboratory features are provided. This updated classification is meant to help in the diagnostic approach to patients with these diseases. PMID:22566844

Recent Developments in the NIST Atomic Databases

NASA Astrophysics Data System (ADS)

Kramida, Alexander

2011-05-01

New versions of the NIST Atomic Spectra Database (ASD, v. 4.0) and three bibliographic databases (Atomic Energy Levels and Spectra, v. 2.0, Atomic Transition Probabilities, v. 9.0, and Atomic Line Broadening and Shapes, v. 3.0) have recently been released. In this contribution I will describe the main changes in the way users get the data through the Web. The contents of ASD have been significantly extended. In particular, the data on highly ionized tungsten (W III-LXXIV) have been added from a recently published NIST compilation. The tables for Fe I and Fe II have been replaced with newer, much more extensive lists (10000 lines for Fe I). The other updated or new spectra include H, D, T, He I-II, Li I-III, Be I-IV, B I-V, C I-II, N I-II, O I-II, Na I-X, K I-XIX, and Hg I. The new version of ASD now incorporates data on isotopes of several elements. I will describe some of the issues the NIST ASD Team faces when updating the data.

Recent Developments in the NIST Atomic Databases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kramida, Alexander

New versions of the NIST Atomic Spectra Database (ASD, v. 4.0) and three bibliographic databases (Atomic Energy Levels and Spectra, v. 2.0, Atomic Transition Probabilities, v. 9.0, and Atomic Line Broadening and Shapes, v. 3.0) have recently been released. In this contribution I will describe the main changes in the way users get the data through the Web. The contents of ASD have been significantly extended. In particular, the data on highly ionized tungsten (W III-LXXIV) have been added from a recently published NIST compilation. The tables for Fe I and Fe II have been replaced with newer, much moremore » extensive lists (10000 lines for Fe I). The other updated or new spectra include H, D, T, He I-II, Li I-III, Be I-IV, B I-V, C I-II, N I-II, O I-II, Na I-X, K I-XIX, and Hg I. The new version of ASD now incorporates data on isotopes of several elements. I will describe some of the issues the NIST ASD Team faces when updating the data.« less

76 FR 20249 - Update Station License Expiration Dates

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-12

... the expiration dates listed both in the Commission's data base and on the broadcast stations' most... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [DA 11-488] Update Station License Expiration... radio and television broadcast stations. The current version of the rule specifies license expiration...

EPA Releases Update to Popular School Integrated Pest Management Publication

EPA Pesticide Factsheets

An updated version reflects recent innovations in school IPM, provides links to new information, and has been redesigned into an easily printable format. It provides an overview of IPM and details the steps a school can follow to establish an IPM program.

The Mpi-M Aerosol Climatology (MAC)

NASA Astrophysics Data System (ADS)

Kinne, S.

2014-12-01

Monthly gridded global data-sets for aerosol optical properties (AOD, SSA and g) and for aerosol microphysical properties (CCN and IN) offer a (less complex) alternate path to include aerosol radiative effects and aerosol impacts on cloud-microphysics in global simulations. Based on merging AERONET sun-/sky-photometer data onto background maps provided by AeroCom phase 1 modeling output and AERONET sun-/the MPI-M Aerosol Climatology (MAC) version 1 was developed and applied in IPCC simulations with ECHAM and as ancillary data-set in satellite-based global data-sets. An updated version 2 of this climatology will be presented now applying central values from the more recent AeroCom phase 2 modeling and utilizing the better global coverage of trusted sun-photometer data - including statistics from the Marine Aerosol network (MAN). Applications include spatial distributions of estimates for aerosol direct and aerosol indirect radiative effects.

The NASA Ames PAH IR Spectroscopic Database: Computational Version 3.00 with Updated Content and the Introduction of Multiple Scaling Factors

NASA Astrophysics Data System (ADS)

Bauschlicher, Charles W., Jr.; Ricca, A.; Boersma, C.; Allamandola, L. J.

2018-02-01

Version 3.00 of the library of computed spectra in the NASA Ames PAH IR Spectroscopic Database (PAHdb) is described. Version 3.00 introduces the use of multiple scale factors, instead of the single scaling factor used previously, to align the theoretical harmonic frequencies with the experimental fundamentals. The use of multiple scale factors permits the use of a variety of basis sets; this allows new PAH species to be included in the database, such as those containing oxygen, and yields an improved treatment of strained species and those containing nitrogen. In addition, the computed spectra of 2439 new PAH species have been added. The impact of these changes on the analysis of an astronomical spectrum through database-fitting is considered and compared with a fit using Version 2.00 of the library of computed spectra. Finally, astronomical constraints are defined for the PAH spectral libraries in PAHdb.

SAM Photovoltaic Model Technical Reference 2016 Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gilman, Paul; DiOrio, Nicholas A; Freeman, Janine M

This manual describes the photovoltaic performance model in the System Advisor Model (SAM) software, Version 2016.3.14 Revision 4 (SSC Version 160). It is an update to the 2015 edition of the manual, which describes the photovoltaic model in SAM 2015.1.30 (SSC 41). This new edition includes corrections of errors in the 2015 edition and descriptions of new features introduced in SAM 2016.3.14, including: 3D shade calculator Battery storage model DC power optimizer loss inputs Snow loss model Plane-of-array irradiance input from weather file option Support for sub-hourly simulations Self-shading works with all four subarrays, and uses same algorithm for fixedmore » arrays and one-axis tracking Linear self-shading algorithm for thin-film modules Loss percentages replace derate factors. The photovoltaic performance model is one of the modules in the SAM Simulation Core (SSC), which is part of both SAM and the SAM SDK. SAM is a user-friedly desktop application for analysis of renewable energy projects. The SAM SDK (Software Development Kit) is for developers writing their own renewable energy analysis software based on SSC. This manual is written for users of both SAM and the SAM SDK wanting to learn more about the details of SAM's photovoltaic model.« less

RAID v2.0: an updated resource of RNA-associated interactions across organisms.

PubMed

Yi, Ying; Zhao, Yue; Li, Chunhua; Zhang, Lin; Huang, Huiying; Li, Yana; Liu, Lanlan; Hou, Ping; Cui, Tianyu; Tan, Puwen; Hu, Yongfei; Zhang, Ting; Huang, Yan; Li, Xiaobo; Yu, Jia; Wang, Dong

2017-01-04

With the development of biotechnologies and computational prediction algorithms, the number of experimental and computational prediction RNA-associated interactions has grown rapidly in recent years. However, diverse RNA-associated interactions are scattered over a wide variety of resources and organisms, whereas a fully comprehensive view of diverse RNA-associated interactions is still not available for any species. Hence, we have updated the RAID database to version 2.0 (RAID v2.0, www.rna-society.org/raid/) by integrating experimental and computational prediction interactions from manually reading literature and other database resources under one common framework. The new developments in RAID v2.0 include (i) over 850-fold RNA-associated interactions, an enhancement compared to the previous version; (ii) numerous resources integrated with experimental or computational prediction evidence for each RNA-associated interaction; (iii) a reliability assessment for each RNA-associated interaction based on an integrative confidence score; and (iv) an increase of species coverage to 60. Consequently, RAID v2.0 recruits more than 5.27 million RNA-associated interactions, including more than 4 million RNA-RNA interactions and more than 1.2 million RNA-protein interactions, referring to nearly 130 000 RNA/protein symbols across 60 species. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

The NASA Modern Era Reanalysis for Research and Applications, Version-2 (MERRA-2)

NASA Astrophysics Data System (ADS)

Gelaro, R.; McCarty, W.; Molod, A.; Suarez, M.; Takacs, L.; Todling, R.

2014-12-01

The NASA Modern Era Reanalysis for Research Applications Version-2 (MERRA-2) is a reanalysis for the satellite era using an updated version of the Goddard Earth Observing System Data Assimilation System Version-5 (GEOS-5) produced by the Global Modeling and Assimilation Office (GMAO). MERRA-2 will assimilate meteorological and aerosol observations not available to MERRA and includes improvements to the GEOS-5 model and analysis scheme so as to provide an ongoing climate analysis beyond MERRA's terminus. MERRA-2 will also serve as a development milestone for a future GMAO coupled Earth system analysis. Production of MERRA-2 began in June 2014 in four processing streams, with convergence to a single near-real time climate analysis expected by early 2015. This talk provides an overview of the MERRA-2 system developments and key science results. For example, compared with MERRA, MERRA-2 exhibits a well-balanced relationship between global precipitation and evaporation, with significantly reduced sensitivity to changes in the global observing system through time. Other notable improvements include reduced biases in the tropical middle- and upper-tropospheric wind and near-surface temperature over continents.

Implications of Version 8 TOMS and SBUV Data for Long-Term Trend Analysis

NASA Technical Reports Server (NTRS)

Frith, Stacey M.

2004-01-01

Total ozone data from the Total Ozone Mapping Spectrometer (TOMS) and profile/total ozone data from the Solar Backscatter Ultraviolet (SBUV; SBW/2) series of instruments have recently been reprocessed using new retrieval algorithms (referred to as Version 8 for both) and updated calibrations. In this paper, we incorporate the Version 8 data into a TOMS/SBW merged total ozone data set and an S B W merged profile ozone data set. The Total Merged Ozone Data (Total MOD) combines data from multiple TOMS and SBW instruments to form an internally consistent global data set with virtually complete time coverage from October 1978 through December 2003. Calibration differences between instruments are accounted for using external adjustments based on instrument intercomparisons during overlap periods. Previous results showed errors due to aerosol loading and sea glint are significantly reduced in the V8 TOMS retrievals. Using SBW as a transfer standard, calibration differences between V8 Nimbus 7 and Earth Probe TOMS data are approx. 1.3%, suggesting small errors in calibration remain. We will present updated total ozone long-term trends based on the Version 8 data. The Profile Merged Ozone Data (Profile MOD) data set is constructed using data from the SBUV series of instruments. In previous versions, SAGE data were used to establish the long-term external calibration of the combined data set. The SBW Version 8 we assess the V8 profile data through comparisons with SAGE and between SBW instruments in overlap periods. We then construct a consistently-calibrated long term time series. Updated zonal mean trends as a function of altitude and season from the new profile data set will be shown, and uncertainties in determining the best long-term calibration will be discussed.

The CAM-ICU has now a French "official" version. The translation process of the 2014 updated Complete Training Manual of the Confusion Assessment Method for the Intensive Care Unit in French (CAM-ICU.fr).

PubMed

Chanques, Gérald; Garnier, Océane; Carr, Julie; Conseil, Matthieu; de Jong, Audrey; Rowan, Christine M; Ely, E Wesley; Jaber, Samir

2017-10-01

Delirium is common in Intensive-Care-Unit (ICU) patients but under-recognized by bed-side clinicians when not using validated delirium-screening tools. The Confusion-Assessment-Method for the ICU (CAM-ICU) has demonstrated very good psychometric properties, and has been translated into many different languages though not into French. We undertook this opportunity to describe the translation process. The translation was performed following recommended guidelines. The updated method published in 2014 including introduction letters, worksheet and flowsheet for bed-side use, the method itself, case-scenarios for training and Frequently-Asked-Questions (32 pages) was translated into French language by a neuropsychological researcher who was not familiar with the original method. Then, the whole method was back-translated by a native English-French bilingual speaker. The new English version was compared to the original one by the Vanderbilt University ICU-delirium-team. Discrepancies were discussed between the two teams before final approval of the French version. The entire process took one year. Among the 3692 words of the back-translated version of the method itself, 18 discrepancies occurred. Eight (44%) lead to changes in the final version. Details of the translation process are provided. The French version of CAM-ICU is now available for French-speaking ICUs. The CAM-ICU is provided with its complete training-manual that was challenging to translate following recommended process. While many such translations have been done for other clinical tools, few have published the details of the process itself. We hope that the availability of such teaching material will now facilitate a large implementation of delirium-screening in French-speaking ICUs. Copyright © 2017 Société française d'anesthésie et de réanimation (Sfar). All rights reserved.

NPIDB: Nucleic acid-Protein Interaction DataBase.

PubMed

Kirsanov, Dmitry D; Zanegina, Olga N; Aksianov, Evgeniy A; Spirin, Sergei A; Karyagina, Anna S; Alexeevski, Andrei V

2013-01-01

The Nucleic acid-Protein Interaction DataBase (http://npidb.belozersky.msu.ru/) contains information derived from structures of DNA-protein and RNA-protein complexes extracted from the Protein Data Bank (3846 complexes in October 2012). It provides a web interface and a set of tools for extracting biologically meaningful characteristics of nucleoprotein complexes. The content of the database is updated weekly. The current version of the Nucleic acid-Protein Interaction DataBase is an upgrade of the version published in 2007. The improvements include a new web interface, new tools for calculation of intermolecular interactions, a classification of SCOP families that contains DNA-binding protein domains and data on conserved water molecules on the DNA-protein interface.

Pediatric complex chronic conditions classification system version 2: updated for ICD-10 and complex medical technology dependence and transplantation

PubMed Central

2014-01-01

Background The pediatric complex chronic conditions (CCC) classification system, developed in 2000, requires revision to accommodate the International Classification of Disease 10th Revision (ICD-10). To update the CCC classification system, we incorporated ICD-9 diagnostic codes that had been either omitted or incorrectly specified in the original system, and then translated between ICD-9 and ICD-10 using General Equivalence Mappings (GEMs). We further reviewed all codes in the ICD-9 and ICD-10 systems to include both diagnostic and procedural codes indicative of technology dependence or organ transplantation. We applied the provisional CCC version 2 (v2) system to death certificate information and 2 databases of health utilization, reviewed the resulting CCC classifications, and corrected any misclassifications. Finally, we evaluated performance of the CCC v2 system by assessing: 1) the stability of the system between ICD-9 and ICD-10 codes using data which included both ICD-9 codes and ICD-10 codes; 2) the year-to-year stability before and after ICD-10 implementation; and 3) the proportions of patients classified as having a CCC in both the v1 and v2 systems. Results The CCC v2 classification system consists of diagnostic and procedural codes that incorporate a new neonatal CCC category as well as domains of complexity arising from technology dependence or organ transplantation. CCC v2 demonstrated close comparability between ICD-9 and ICD-10 and did not detect significant discontinuity in temporal trends of death in the United States. Compared to the original system, CCC v2 resulted in a 1.0% absolute (10% relative) increase in the number of patients identified as having a CCC in national hospitalization dataset, and a 0.4% absolute (24% relative) increase in a national emergency department dataset. Conclusions The updated CCC v2 system is comprehensive and multidimensional, and provides a necessary update to accommodate widespread implementation of ICD-10. PMID:25102958

The 2014 updated version of the Confusion Assessment Method for the Intensive Care Unit compared to the 5th version of the Diagnostic and Statistical Manual of Mental Disorders and other current methods used by intensivists.

PubMed

Chanques, Gérald; Ely, E Wesley; Garnier, Océane; Perrigault, Fanny; Eloi, Anaïs; Carr, Julie; Rowan, Christine M; Prades, Albert; de Jong, Audrey; Moritz-Gasser, Sylvie; Molinari, Nicolas; Jaber, Samir

2018-03-01

One third of patients admitted to an intensive care unit (ICU) will develop delirium. However, delirium is under-recognized by bedside clinicians without the use of delirium screening tools, such as the Intensive Care Delirium Screening Checklist (ICDSC) or the Confusion Assessment Method for the ICU (CAM-ICU). The CAM-ICU was updated in 2014 to improve its use by clinicians throughout the world. It has never been validated compared to the new reference standard, the Diagnostic and Statistical Manual of Mental Disorders 5th version (DSM-5). We made a prospective psychometric study in a 16-bed medical-surgical ICU of a French academic hospital, to measure the diagnostic performance of the 2014 updated CAM-ICU compared to the DSM-5 as the reference standard. We included consecutive adult patients with a Richmond Agitation Sedation Scale (RASS) ≥ -3, without preexisting cognitive disorders, psychosis or cerebral injury. Delirium was independently assessed by neuropsychological experts using an operationalized approach to DSM-5, by investigators using the CAM-ICU and the ICDSC, by bedside clinicians and by ICU patients. The sensitivity, specificity, positive and negative predictive values were calculated considering neuropsychologist DSM-5 assessments as the reference standard (primary endpoint). CAM-ICU inter-observer agreement, as well as that between delirium diagnosis methods and the reference standard, was summarized using κ coefficients, which were subsequently compared using the Z-test. Delirium was diagnosed by experts in 38% of the 108 patients included for analysis. The CAM-ICU had a sensitivity of 83%, a specificity of 100%, a positive predictive value of 100% and a negative predictive value of 91%. Compared to the reference standard, the CAM-ICU had a significantly (p < 0.05) higher agreement (κ = 0.86 ± 0.05) than the physicians,' residents' and nurses' diagnoses (κ = 0.65 ± 0.09; 0.63 ± 0.09; 0.61 ± 0.09, respectively), as well as the patient's own impression of feeling delirious (κ = 0.02 ± 0.11). Differences between the ICDSC (κ = 0.69 ± 0.07) and CAM-ICU were not significant (p = 0.054). The CAM-ICU demonstrated a high reliability for inter-observer agreement (κ = 0.87 ± 0.06). The 2014 updated version of the CAM-ICU is valid according to DSM-5 criteria and reliable regarding inter-observer agreement in a research setting. Delirium remains under-recognized by bedside clinicians.

Documentation for the machine-readable version of A Catalogue of Extragalactic Radio Source Identifications (Veron-Cetty and Veron 1983)

NASA Technical Reports Server (NTRS)

Warren, W. H., Jr.

1983-01-01

Detailed descriptions of the data and reference files of the updated and final version of the machine-readable catalog are given. The computerized catalog has greatly expanded since the original published version (1974), and additional information is given. A separate reference file contains bibliographical citations ordered simultaneously by numerical reference and alphabetically by author.

Diffusive Public Goods and Coexistence of Cooperators and Cheaters on a 1D Lattice

PubMed Central

Scheuring, István

2014-01-01

Many populations of cells cooperate through the production of extracellular materials. These materials (enzymes, siderophores) spread by diffusion and can be applied by both the cooperator and cheater (non-producer) cells. In this paper the problem of coexistence of cooperator and cheater cells is studied on a 1D lattice where cooperator cells produce a diffusive material which is beneficial to the individuals according to the local concentration of this public good. The reproduction success of a cell increases linearly with the benefit in the first model version and increases non-linearly (saturates) in the second version. Two types of update rules are considered; either the cooperative cell stops producing material before death (death-production-birth, DpB) or it produces the common material before it is selected to die (production-death-birth, pDB). The empty space is occupied by its neighbors according to their replication rates. By using analytical and numerical methods I have shown that coexistence of the cooperator and cheater cells is possible although atypical in the linear version of this 1D model if either DpB or pDB update rule is assumed. While coexistence is impossible in the non-linear model with pDB update rule, it is one of the typical behaviors in case of the non-linear model with DpB update rule. PMID:25025985

Development and Validation of the Pediatric Medical Complexity Algorithm (PMCA) Version 3.0.

PubMed

Simon, Tamara D; Haaland, Wren; Hawley, Katherine; Lambka, Karen; Mangione-Smith, Rita

2018-02-26

To modify the Pediatric Medical Complexity Algorithm (PMCA) to include both International Classification of Diseases, Ninth and Tenth Revisions, Clinical Modification (ICD-9/10-CM) codes for classifying children with chronic disease (CD) by level of medical complexity and to assess the sensitivity and specificity of the new PMCA version 3.0 for correctly identifying level of medical complexity. To create version 3.0, PMCA version 2.0 was modified to include ICD-10-CM codes. We applied PMCA version 3.0 to Seattle Children's Hospital data for children with ≥1 emergency department (ED), day surgery, and/or inpatient encounter from January 1, 2016, to June 30, 2017. Starting with the encounter date, up to 3 years of retrospective discharge data were used to classify children as having complex chronic disease (C-CD), noncomplex chronic disease (NC-CD), and no CD. We then selected a random sample of 300 children (100 per CD group). Blinded medical record review was conducted to ascertain the levels of medical complexity for these 300 children. The sensitivity and specificity of PMCA version 3.0 was assessed. PMCA version 3.0 identified children with C-CD with 86% sensitivity and 86% specificity, children with NC-CD with 65% sensitivity and 84% specificity, and children without CD with 77% sensitivity and 93% specificity. PMCA version 3.0 is an updated publicly available algorithm that identifies children with C-CD, who have accessed tertiary hospital emergency department, day surgery, or inpatient care, with very good sensitivity and specificity when applied to hospital discharge data and with performance to earlier versions of PMCA. Copyright © 2018 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

Human factors design guide update (report number DOT/FAA/CT-96/01) : a revision to chapter 5--automation guidelines.

DOT National Transportation Integrated Search

2001-12-01

This document contains an updated and expanded version of the Automation chapter of the Human Factors Design Guide. A research : team of human factors experts evaluated the existing guidelines for relevance, clarity, and usability. The research team ...

BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface

PubMed Central

Lee, A J; Cunningham, A P; Kuchenbaecker, K B; Mavaddat, N; Easton, D F; Antoniou, A C

2014-01-01

Background: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA) is a risk prediction model that is used to compute probabilities of carrying mutations in the high-risk breast and ovarian cancer susceptibility genes BRCA1 and BRCA2, and to estimate the future risks of developing breast or ovarian cancer. In this paper, we describe updates to the BOADICEA model that extend its capabilities, make it easier to use in a clinical setting and yield more accurate predictions. Methods: We describe: (1) updates to the statistical model to include cancer incidences from multiple populations; (2) updates to the distributions of tumour pathology characteristics using new data on BRCA1 and BRCA2 mutation carriers and women with breast cancer from the general population; (3) improvements to the computational efficiency of the algorithm so that risk calculations now run substantially faster; and (4) updates to the model's web interface to accommodate these new features and to make it easier to use in a clinical setting. Results: We present results derived using the updated model, and demonstrate that the changes have a significant impact on risk predictions. Conclusion: All updates have been implemented in a new version of the BOADICEA web interface that is now available for general use: http://ccge.medschl.cam.ac.uk/boadicea/. PMID:24346285

National Hydropower Plant Dataset, Version 2 (FY18Q3)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samu, Nicole; Kao, Shih-Chieh; O'Connor, Patrick

The National Hydropower Plant Dataset, Version 2 (FY18Q3) is a geospatially comprehensive point-level dataset containing locations and key characteristics of U.S. hydropower plants that are currently either in the hydropower development pipeline (pre-operational), operational, withdrawn, or retired. These data are provided in GIS and tabular formats with corresponding metadata for each. In addition, we include access to download 2 versions of the National Hydropower Map, which was produced with these data (i.e. Map 1 displays the geospatial distribution and characteristics of all operational hydropower plants; Map 2 displays the geospatial distribution and characteristics of operational hydropower plants with pumped storagemore » and mixed capabilities only). This dataset is a subset of ORNL's Existing Hydropower Assets data series, updated quarterly as part of ORNL's National Hydropower Asset Assessment Program.« less

AN OVERVIEW OF EPANET VERSION 3.0

EPA Science Inventory

EPANET is a widely used public domain software package for modeling the hydraulic and water quality behavior of water distribution systems over an extended period of time. The last major update to the code was version 2.0 released in 2000 (Rossman, 2000). Since that time there ha...

Publisher Correction: Ticks parasitised feathered dinosaurs as revealed by Cretaceous amber assemblages.

PubMed

Peñalver, Enrique; Arillo, Antonio; Delclòs, Xavier; Peris, David; Grimaldi, David A; Anderson, Scott R; Nascimbene, Paul C; Fuente, Ricardo Pérez-de la

2018-01-30

The originally published version of this Article was updated shortly after publication to add the word 'Ticks' to the title, following its inadvertent removal during the production process. This has now been corrected in both the PDF and HTML versions of the Article.

TRMM Version 7 Near-Realtime Data Products

NASA Technical Reports Server (NTRS)

Tocker, Erich Franz; Kelley, Owen

2012-01-01

The TRMM data system has been providing near-realtime data products to the community since late 1999. While the TRMM project never had near-realtime production requirements, the science and applications communities had a great interest in receiving TRMM data as quickly as possible. As a result these NRT data are provided under a best-effort scenario but with the objective of having the swath data products available within three hours of data collection 90% of the time. In July of 2011 the Joint Precipitation Measurement Missions Science Team (JPST) authorized the reprocessing of TRMM mission data using the new version 7 algorithms. The reprocessing of the 14+ years of the mission was concluded within 30 days. Version 7 algorithms had substantial changes in the data product file formats both for data and metadata. In addition, the algorithms themselves had major modifications and improvements. The general approach to versioning up the NRT is to wait for the regular production algorithms to have run for a while and shake out any issues that might arise from the new version before updating the NRT products. Because of the substantial changes in data/metadata formats as well as the algorithm improvements themselves, the update of NRT to V7 followed an even more conservative path than usual. This was done to ensure that applications agencies and other users of the TRMM NRT would not be faces with short-timeframes for conversion to the new format. This paper will describe the process by which the TRMM NRT was updated to V7 and the V7 data products themselves.

Users manual for the improved NASA Lewis ice accretion code LEWICE 1.6

NASA Technical Reports Server (NTRS)

Wright, William B.

1995-01-01

This report is intended as an update/replacement to NASA CR 185129 'User's Manual for the NASALewis Ice Accretion Prediction Code (LEWICE)' and as an update to NASA CR 195387 'Update to the NASA Lewis Ice Accretion Code LEWICE'. In addition to describing the changes specifically made for this version, information from previous manuals will be duplicated so that the user will not need three manuals to use this code.

Resource Tracking Model Updates and Trade Studies

NASA Technical Reports Server (NTRS)

Chambliss, Joe; Stambaugh, Imelda; Moore, Michael

2016-01-01

The Resource Tracking Model has been updated to capture system manager and project manager inputs. Both the Trick/General Use Nodal Network Solver Resource Tracking Model (RTM) simulator and the RTM mass balance spreadsheet have been revised to address inputs from system managers and to refine the way mass balance is illustrated. The revisions to the RTM included the addition of a Plasma Pyrolysis Assembly (PPA) to recover hydrogen from Sabatier Reactor methane, which was vented in the prior version of the RTM. The effect of the PPA on the overall balance of resources in an exploration vehicle is illustrated in the increased recycle of vehicle oxygen. Case studies have been run to show the relative effect of performance changes on vehicle resources.

Toms, Coons, Mulattoes, Mammies, & Bucks: An Interpretive History of Blacks in American Films. New Expanded Edition.

ERIC Educational Resources Information Center

Bogle, Donald

This classic, definitive study of Black images in American movies has been completely revised and updated to include new chapters on the films of the 1970s and 1980s. This new version of the book reveals the way in which the image of Blacks in American movies has changed--and also the way in which it has remained the same. Following a preface to…

The LARSYS Educational Package: Instructor's Notes for Use with the Data 100

NASA Technical Reports Server (NTRS)

Lindenlaub, J. C.; Russell, J. D.

1977-01-01

The LARSYS Educational Package is a set of instructional materials developed to train people to analyze remotely sensed multispectral data using LARSYS, a computer software system. The materials included in this volume have been designed to assist LARSYS instructors as they guide students through the LARSYS Educational Package. All of the materials have been updated from the previous version to reflect the use of a Data 100 Remote Terminal.

Proposed modifications to the RCRA post-closure permit for the Upper East Fork Poplar Creek Hydrogeologic Regime at the U.S. Department of Energy Y-12 Plant, Oak Ridge, Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-05-01

This report presents proposed modifications to the Resource Conservation and Recovery Act (RCRA) Post-Closure Permit (PCP) for the Upper East Fork Poplar Creek Hydrogeologic Regime (permit number TNHW-088, EPA ID No. TN3 89 009 0001). The modifications are proposed to: (1) revise the current text for two of the Permit Conditions included in Permit Section II - General Facility Conditions, and (2) update the PCP with revised versions of the Y-12 Plant Groundwater Protection Program (GWPP) technical field procedures included in several of the Permit Attachments. The updated field procedures and editorial revisions are Class 1 permit modifications, as specifiedmore » in Title 40, Code of Federal Regulations (CFR) {section}270.42; Appendix I - Classification of Permit Modifications. These modifications are summarized below.« less

Coal Export Financing: methods and trends (from the series Market Guides for Steam-Coal Exports from Appalachia). Report for January 1982-December 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1984-05-01

The new 1984 version of Coal Export Financing is published as a joint effort of the ARC and the U.S. Department of Commerce. It was updated to include information on new trends and developments that have occurred since late 1982 in coal-export financing as a result of the intense price competition from other coal-exporting nations. This includes new information on developments under the Export Trading Company Act of 1982, reverse investments, and barter/countertrade. Information previously provided on political and commercial risk insurance and on governmental assistance has been expanded to reflect the increasing importance of these areas. Any information onmore » banks providing coal-export financing services has been updated, as well as expanded to encompass the entire United States, rather than just the Appalachian region.« less

Air Traffic Management Technology Demonstration-1 Concept of Operations (ATD-1 ConOps), Version 3.0

NASA Technical Reports Server (NTRS)

Baxley, Brian T.; Johnson, William C.; Scardina, John; Shay, Richard F.

2016-01-01

This document describes the goals, benefits, technologies, and procedures of the Concept of Operations (ConOps) for the Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1), and provides an update to the previous versions of the document [ref 1 and ref 2].

CET93 and CETPC: An interim updated version of the NASA Lewis computer program for calculating complex chemical equilibria with applications

NASA Technical Reports Server (NTRS)

Mcbride, Bonnie J.; Reno, Martin A.; Gordon, Sanford

1994-01-01

The NASA Lewis chemical equilibrium program with applications continues to be improved and updated. The latest version is CET93. This code, with smaller arrays, has been compiled for use on an IBM or IBM-compatible personal computer and is called CETPC. This report is intended to be primarily a users manual for CET93 and CETPC. It does not repeat the more complete documentation of earlier reports on the equilibrium program. Most of the discussion covers input and output files, two new options (ONLY and comments), example problems, and implementation of CETPC.

The CO5 configuration of the 7 km Atlantic Margin Model: large-scale biases and sensitivity to forcing, physics options and vertical resolution

NASA Astrophysics Data System (ADS)

O'Dea, Enda; Furner, Rachel; Wakelin, Sarah; Siddorn, John; While, James; Sykes, Peter; King, Robert; Holt, Jason; Hewitt, Helene

2017-08-01

We describe the physical model component of the standard Coastal Ocean version 5 configuration (CO5) of the European north-west shelf (NWS). CO5 was developed jointly between the Met Office and the National Oceanography Centre. CO5 is designed with the seamless approach in mind, which allows for modelling of multiple timescales for a variety of applications from short-range ocean forecasting to climate projections. The configuration constitutes the basis of the latest update to the ocean and data assimilation components of the Met Office's operational Forecast Ocean Assimilation Model (FOAM) for the NWS. A 30.5-year non-assimilating control hindcast of CO5 was integrated from January 1981 to June 2012. Sensitivity simulations were conducted with reference to the control run. The control run is compared against a previous non-assimilating Proudman Oceanographic Laboratory Coastal Ocean Modelling System (POLCOMS) hindcast of the NWS. The CO5 control hindcast is shown to have much reduced biases compared to POLCOMS. Emphasis in the system description is weighted to updates in CO5 over previous versions. Updates include an increase in vertical resolution, a new vertical coordinate stretching function, the replacement of climatological riverine sources with the pan-European hydrological model E-HYPE, a new Baltic boundary condition and switching from directly imposed atmospheric model boundary fluxes to calculating the fluxes within the model using a bulk formula. Sensitivity tests of the updates are detailed with a view toward attributing observed changes in the new system from the previous system and suggesting future directions of research to further improve the system.

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

PubMed Central

Schellenberger, Jan; Que, Richard; Fleming, Ronan M. T.; Thiele, Ines; Orth, Jeffrey D.; Feist, Adam M.; Zielinski, Daniel C.; Bordbar, Aarash; Lewis, Nathan E.; Rahmanian, Sorena; Kang, Joseph; Hyduke, Daniel R.; Palsson, Bernhard Ø.

2012-01-01

Over the past decade, a growing community of researchers has emerged around the use of COnstraint-Based Reconstruction and Analysis (COBRA) methods to simulate, analyze and predict a variety of metabolic phenotypes using genome-scale models. The COBRA Toolbox, a MATLAB package for implementing COBRA methods, was presented earlier. Here we present a significant update of this in silico ToolBox. Version 2.0 of the COBRA Toolbox expands the scope of computations by including in silico analysis methods developed since its original release. New functions include: (1) network gap filling, (2) 13C analysis, (3) metabolic engineering, (4) omics-guided analysis, and (5) visualization. As with the first version, the COBRA Toolbox reads and writes Systems Biology Markup Language formatted models. In version 2.0, we improved performance, usability, and the level of documentation. A suite of test scripts can now be used to learn the core functionality of the Toolbox and validate results. This Toolbox lowers the barrier of entry to use powerful COBRA methods. PMID:21886097

Problematic Smartphone Use: Investigating Contemporary Experiences Using a Convergent Design

PubMed Central

Harkin, Lydia

2018-01-01

Internet-enabled smartphones are increasingly ubiquitous in the Western world. Research suggests a number of problems can result from mobile phone overuse, including dependence, dangerous and prohibited use. For over a decade, this has been measured by the Problematic Mobile Phone Use Questionnaire (PMPU-Q). Given the rapid developments in mobile technologies, changes of use patterns and possible problematic and addictive use, the aim of the present study was to investigate and validate an updated contemporary version of the PMPU-Q (PMPU-Q-R). A mixed methods convergent design was employed, including a psychometric survey (N = 512) alongside qualitative focus groups (N = 21), to elicit experiences and perceptions of problematic smartphone use. The results suggest the PMPU-Q-R factor structure can be updated to include smartphone dependence, dangerous driving, and antisocial smartphone use factors. Theories of problematic mobile phone use require consideration of the ubiquity and indispensability of smartphones in the present day and age, particularly regarding use whilst driving and in social interactions. PMID:29337883

Problematic Smartphone Use: Investigating Contemporary Experiences Using a Convergent Design.

PubMed

Kuss, Daria J; Harkin, Lydia; Kanjo, Eiman; Billieux, Joel

2018-01-16

Internet-enabled smartphones are increasingly ubiquitous in the Western world. Research suggests a number of problems can result from mobile phone overuse, including dependence, dangerous and prohibited use. For over a decade, this has been measured by the Problematic Mobile Phone Use Questionnaire (PMPU-Q). Given the rapid developments in mobile technologies, changes of use patterns and possible problematic and addictive use, the aim of the present study was to investigate and validate an updated contemporary version of the PMPU-Q (PMPU-Q-R). A mixed methods convergent design was employed, including a psychometric survey ( N = 512) alongside qualitative focus groups ( N = 21), to elicit experiences and perceptions of problematic smartphone use. The results suggest the PMPU-Q-R factor structure can be updated to include smartphone dependence, dangerous driving, and antisocial smartphone use factors. Theories of problematic mobile phone use require consideration of the ubiquity and indispensability of smartphones in the present day and age, particularly regarding use whilst driving and in social interactions.

The Partners in Flight handbook on species assessment Version 2017

USGS Publications Warehouse

Panjabi, Arvind O.; Blancher, Peter J.; Easton, Wendy E.; Stanton, Jessica C.; Demarest, Dean W.; Dettmers, Randy; Rosenberg, Kenneth V.; ,

2017-01-01

6. Evaluating success, making revisions, and setting new objectives for the future. The 2017 PIF Handbook on Species Assessment (2017 PIF Handbook) documents assessment rules and scores used in the Partners in Flight Landbird Conservation Plan: 2016 Revision for Canada and Continental United States (Rosenberg et al. 2016) and The State of North America’s Birds 2016 (NABCI 2016). It updates previous versions of the handbook (Panjabi et al. 2012, 2005, 2001) developed to accompany other PIF applications including Saving Our Shared Birds: Partners in Flight Tri-National Vision for Landbird Conservation (Berlanga et al. 2010) and the North American Landbird Conservation Plan (Rich et al. 2004). All current and past scores, data sources, and other related information are contained in databases hosted by the Bird Conservancy of the Rockies. Scores can be viewed online and downloaded as excel files, including archived versions (http://pif.birdconservancy.org/acad). The current accompanying Avian Conservation Assessment Database (ACAD) holds assessment scores and data for all 1585 native and 18 well-established non-native bird species found in mainland North America south to Panama plus adjacent islands and oceans. The taxonomy follows the American Ornithological Society’s 7th Edition Checklist of North and Middle American Birds, including updates though the 57th supplement, published in 2016 (http://checklist.aou.org/). The ACAD builds on archived PIF databases that hosted only data on the 882 landbirds native to Canada, USA and Mexico. This handbook is presented in two principal sections. Part I details the factors and scoring used by PIF to assess the vulnerability of species at continental and regional scales (i.e. step 1 of the planning approach above). Each assessment factor is based on biological criteria that evaluate distinct components of vulnerability throughout the life cycle of each species across its range. Part II describes the process of how the factors and the corresponding scores can be combined to highlight conservation needs (i.e. step 2 of the planning approach above). Both the scores and the process have evolved over time (Hunter et al. 1992, Carter et al. 2000, Panjabi et al. 2001, 2005, 2012) and continue to be updated in response to external review (Beissinger et al. 2000), broad partner expertise, and the emergence of new data and analytical tools.

Accelerated Leach Testing of GLASS: ALTGLASS Version 3.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trivelpiece, Cory L.; Jantzen, Carol M.; Crawford, Charles L.

The Accelerated Leach Testing of GLASS (ALTGLASS) database is a collection of data from short- and long-term product consistency tests (PCT, ASTM C1285 A and B) on high level waste (HLW) as well as low activity waste (LAW) glasses. The database provides both U.S. and international researchers with an archive of experimental data for the purpose of studying, modeling, or validating existing models of nuclear waste glass corrosion. The ALTGLASS database is maintained and updated by researchers at the Savannah River National Laboratory (SRNL). This newest version, ALTGLASS Version 3.0, has been updated with an additional 503 rows of datamore » representing PCT results from corrosion experiments conducted in the United States by the Savannah River National Laboratory, Pacific Northwest National Laboratory, Argonne National Laboratory, and the Vitreous State Laboratory (SRNL, PNNL, ANL, VSL, respectively) as well as the National Nuclear Laboratory (NNL) in the United Kingdom.« less

GeoGebra 3D from the Perspectives of Elementary Pre-Service Mathematics Teachers Who Are Familiar with a Number of Software Programs

ERIC Educational Resources Information Center

Baltaci, Serdal; Yildiz, Avni

2015-01-01

Each new version of the GeoGebra dynamic mathematics software goes through updates and innovations. One of these innovations is the GeoGebra 5.0 version. This version aims to facilitate 3D instruction by offering opportunities for students to analyze 3D objects. While scanning the previous studies of GeoGebra 3D, it is seen that they mainly focus…

The Community Climate System Model.

NASA Astrophysics Data System (ADS)

Blackmon, Maurice; Boville, Byron; Bryan, Frank; Dickinson, Robert; Gent, Peter; Kiehl, Jeffrey; Moritz, Richard; Randall, David; Shukla, Jagadish; Solomon, Susan; Bonan, Gordon; Doney, Scott; Fung, Inez; Hack, James; Hunke, Elizabeth; Hurrell, James; Kutzbach, John; Meehl, Jerry; Otto-Bliesner, Bette; Saravanan, R.; Schneider, Edwin K.; Sloan, Lisa; Spall, Michael; Taylor, Karl; Tribbia, Joseph; Washington, Warren

2001-11-01

The Community Climate System Model (CCSM) has been created to represent the principal components of the climate system and their interactions. Development and applications of the model are carried out by the U.S. climate research community, thus taking advantage of both wide intellectual participation and computing capabilities beyond those available to most individual U.S. institutions. This article outlines the history of the CCSM, its current capabilities, and plans for its future development and applications, with the goal of providing a summary useful to present and future users. The initial version of the CCSM included atmosphere and ocean general circulation models, a land surface model that was grafted onto the atmosphere model, a sea-ice model, and a flux coupler that facilitates information exchanges among the component models with their differing grids. This version of the model produced a successful 300-yr simulation of the current climate without artificial flux adjustments. The model was then used to perform a coupled simulation in which the atmospheric CO2 concentration increased by 1% per year. In this version of the coupled model, the ocean salinity and deep-ocean temperature slowly drifted away from observed values. A subsequent correction to the roughness length used for sea ice significantly reduced these errors. An updated version of the CCSM was used to perform three simulations of the twentieth century's climate, and several pro-jections of the climate of the twenty-first century. The CCSM's simulation of the tropical ocean circulation has been significantly improved by reducing the background vertical diffusivity and incorporating an anisotropic horizontal viscosity tensor. The meridional resolution of the ocean model was also refined near the equator. These changes have resulted in a greatly improved simulation of both the Pacific equatorial undercurrent and the surface countercurrents. The interannual variability of the sea surface temperature in the central and eastern tropical Pacific is also more realistic in simulations with the updated model. Scientific challenges to be addressed with future versions of the CCSM include realistic simulation of the whole atmosphere, including the middle and upper atmosphere, as well as the troposphere; simulation of changes in the chemical composition of the atmosphere through the incorporation of an integrated chemistry model; inclusion of global, prognostic biogeochemical components for land, ocean, and atmosphere; simulations of past climates, including times of extensive continental glaciation as well as times with little or no ice; studies of natural climate variability on seasonal-to-centennial timescales; and investigations of anthropogenic climate change. In order to make such studies possible, work is under way to improve all components of the model. Plans call for a new version of the CCSM to be released in 2002. Planned studies with the CCSM will require much more computer power than is currently available.

Ray-tracing 3D dust radiative transfer with DART-Ray: code upgrade and public release

NASA Astrophysics Data System (ADS)

Natale, Giovanni; Popescu, Cristina C.; Tuffs, Richard J.; Clarke, Adam J.; Debattista, Victor P.; Fischera, Jörg; Pasetto, Stefano; Rushton, Mark; Thirlwall, Jordan J.

2017-11-01

We present an extensively updated version of the purely ray-tracing 3D dust radiation transfer code DART-Ray. The new version includes five major upgrades: 1) a series of optimizations for the ray-angular density and the scattered radiation source function; 2) the implementation of several data and task parallelizations using hybrid MPI+OpenMP schemes; 3) the inclusion of dust self-heating; 4) the ability to produce surface brightness maps for observers within the models in HEALPix format; 5) the possibility to set the expected numerical accuracy already at the start of the calculation. We tested the updated code with benchmark models where the dust self-heating is not negligible. Furthermore, we performed a study of the extent of the source influence volumes, using galaxy models, which are critical in determining the efficiency of the DART-Ray algorithm. The new code is publicly available, documented for both users and developers, and accompanied by several programmes to create input grids for different model geometries and to import the results of N-body and SPH simulations. These programmes can be easily adapted to different input geometries, and for different dust models or stellar emission libraries.

Medicare program; prospective payment system and consolidated billing for skilled nursing facilities for FY 2010; minimum data set, version 3.0 for skilled nursing facilities and Medicaid nursing facilities. Final rule.

PubMed

2009-08-11

This final rule updates the payment rates used under the prospective payment system (PPS) for skilled nursing facilities (SNFs), for fiscal year (FY) 2010. In addition, it recalibrates the case-mix indexes so that they more accurately reflect parity in expenditures related to the implementation of case-mix refinements in January 2006. It also discusses the results of our ongoing analysis of nursing home staff time measurement data collected in the Staff Time and Resource Intensity Verification project, as well as a new Resource Utilization Groups, version 4 case-mix classification model for FY 2011 that will use the updated Minimum Data Set 3.0 resident assessment for case-mix classification. In addition, this final rule discusses the public comments that we have received on these and other issues, including a possible requirement for the quarterly reporting of nursing home staffing data, as well as on applying the quality monitoring mechanism in place for all other SNF PPS facilities to rural swing-bed hospitals. Finally, this final rule revises the regulations to incorporate certain technical corrections.

Aeroacoustic Analysis of Turbofan Noise Generation

NASA Technical Reports Server (NTRS)

Meyer, Harold D.; Envia, Edmane

1996-01-01

This report provides an updated version of analytical documentation for the V072 Rotor Wake/Stator Interaction Code. It presents the theoretical derivation of the equations used in the code and, where necessary, it documents the enhancements and changes made to the original code since its first release. V072 is a package of FORTRAN computer programs which calculate the in-duct acoustic modes excited by a fan/stator stage operating in a subsonic mean flow. Sound is generated by the stator vanes interacting with the mean wakes of the rotor blades. In this updated version, only the tonal noise produced at the blade passing frequency and its harmonics, is described. The broadband noise component analysis, which was part of the original report, is not included here. The code provides outputs of modal pressure and power amplitudes generated by the rotor-wake/stator interaction. The rotor/stator stage is modeled as an ensemble of blades and vanes of zero camber and thickness enclosed within an infinite hard-walled annular duct. The amplitude of each propagating mode is computed and summed to obtain the harmonics of sound power flux within the duct for both upstream and downstream propagating modes.

PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database.

PubMed

Wang, Xia; Shen, Yihang; Wang, Shiwei; Li, Shiliang; Zhang, Weilin; Liu, Xiaofeng; Lai, Luhua; Pei, Jianfeng; Li, Honglin

2017-07-03

The PharmMapper online tool is a web server for potential drug target identification by reversed pharmacophore matching the query compound against an in-house pharmacophore model database. The original version of PharmMapper includes more than 7000 target pharmacophores derived from complex crystal structures with corresponding protein target annotations. In this article, we present a new version of the PharmMapper web server, of which the backend pharmacophore database is six times larger than the earlier one, with a total of 23 236 proteins covering 16 159 druggable pharmacophore models and 51 431 ligandable pharmacophore models. The expanded target data cover 450 indications and 4800 molecular functions compared to 110 indications and 349 molecular functions in our last update. In addition, the new web server is united with the statistically meaningful ranking of the identified drug targets, which is achieved through the use of standard scores. It also features an improved user interface. The proposed web server is freely available at http://lilab.ecust.edu.cn/pharmmapper/. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Department of Defense Command and Control Implementation Plan, Version 1.0

DTIC Science & Technology

2009-10-01

needs • Be maintained by the C2 Capability Portfolio Manager ( CPM ) and updated every 2 years to address emerging C2 operational concepts, changing and...including sources managed by the C2 CPM as well as other CPMs (e.g., Net- Centric, Battlespace Awareness, and Logistics). C2 platforms and facilities with...incremental delivery of improved capabilities over time. Implementation planning is a C2 CPM -facilitated activity that involves identifying and

Automated and Assistive Tools for Accelerated Code migration of Scientific Computing on to Heterogeneous MultiCore Systems

DTIC Science & Technology

2017-04-13

modelling code, a parallel benchmark , and a communication avoiding version of the QR algorithm. Further, several improvements to the OmpSs model were...movement; and a port of the dynamic load balancing library to OmpSs. Finally, several updates to the tools infrastructure were accomplished, including: an...OmpSs: a basic algorithm on image processing applications, a mini application representative of an ocean modelling code, a parallel benchmark , and a

Using the Violence Risk Scale-Sexual Offense version in sexual violence risk assessments: Updated risk categories and recidivism estimates from a multisite sample of treated sexual offenders.

PubMed

Olver, Mark E; Mundt, James C; Thornton, David; Beggs Christofferson, Sarah M; Kingston, Drew A; Sowden, Justina N; Nicholaichuk, Terry P; Gordon, Audrey; Wong, Stephen C P

2018-04-30

The present study sought to develop updated risk categories and recidivism estimates for the Violence Risk Scale-Sexual Offense version (VRS-SO; Wong, Olver, Nicholaichuk, & Gordon, 2003-2017), a sexual offender risk assessment and treatment planning tool. The overarching purpose was to increase the clarity and accuracy of communicating risk assessment information that includes a systematic incorporation of new information (i.e., change) to modify risk estimates. Four treated samples of sexual offenders with VRS-SO pretreatment, posttreatment, and Static-99R ratings were combined with a minimum follow-up period of 10-years postrelease (N = 913). Logistic regression was used to model 5- and 10-year sexual and violent (including sexual) recidivism estimates across 6 different regression models employing specific risk and change score information from the VRS-SO and/or Static-99R. A rationale is presented for clinical applications of select models and the necessity of controlling for baseline risk when utilizing change information across repeated assessments. Information concerning relative risk (percentiles) and absolute risk (recidivism estimates) is integrated with common risk assessment language guidelines to generate new risk categories for the VRS-SO. Guidelines for model selection and forensic clinical application of the risk estimates are discussed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Update of the Healthy Eating Index: HEI-2010

PubMed Central

Guenther, Patricia M.; Kirkpatrick, Sharon I.; Reedy, Jill; Hiza, Hazel A.B.; Kuczynski, Kevin J.; Kahle, Lisa L.; Krebs-Smith, Susan M.

2013-01-01

The Healthy Eating Index (HEI) is a measure of diet quality in terms of conformance with federal dietary guidance. Publication of the Dietary Guidelines for Americans, 2010 prompted an interagency working group to update the HEI. The HEI-2010 retains several features of the 2005 version: (1) it has 12 components, many unchanged, including 9 adequacy and 3 moderation components; (2) it uses a density approach to set standards, e.g., per 1000 calories or as a percent of calories; and (3) it employs least-restrictive standards, i.e., those that are easiest to achieve among recommendations that vary by energy level, sex, and/or age. Changes to the index include: (1) Greens and Beans replaces Dark Green and Orange Vegetables and Legumes; (2) Seafood and Plant Proteins has been added to capture specific choices from the protein group; (3) Fatty Acids, a ratio of poly- and mono-unsaturated to saturated fatty acids, replaces Oils and Saturated Fat to acknowledge the recommendation to replace saturated fat with mono-and polyunsaturated fatty acids; and (4) a moderation component, Refined Grains, replaces the adequacy component, Total Grains, to assess over-consumption. The HEI-2010 captures the key recommendations of the 2010 Dietary Guidelines and, like earlier versions, will be used to assess the diet quality of the U.S. population and subpopulations, in evaluating interventions, in dietary patterns research, and to evaluate various aspects of the food environment. PMID:23415502

Evolving learning rules and emergence of cooperation in spatial prisoner's dilemma.

PubMed

Moyano, Luis G; Sánchez, Angel

2009-07-07

In the evolutionary Prisoner's dilemma (PD) game, agents play with each other and update their strategies in every generation according to some microscopic dynamical rule. In its spatial version, agents do not play with every other but, instead, interact only with their neighbours, thus mimicking the existing of a social or contact network that defines who interacts with whom. In this work, we explore evolutionary, spatial PD systems consisting of two types of agents, each with a certain update (reproduction, learning) rule. We investigate two different scenarios: in the first case, update rules remain fixed for the entire evolution of the system; in the second case, agents update both strategy and update rule in every generation. We show that in a well-mixed population the evolutionary outcome is always full defection. We subsequently focus on two-strategy competition with nearest-neighbour interactions on the contact network and synchronised update of strategies. Our results show that, for an important range of the parameters of the game, the final state of the system is largely different from that arising from the usual setup of a single, fixed dynamical rule. Furthermore, the results are also very different if update rules are fixed or evolve with the strategies. In these respect, we have studied representative update rules, finding that some of them may become extinct while others prevail. We describe the new and rich variety of final outcomes that arise from this co-evolutionary dynamics. We include examples of other neighbourhoods and asynchronous updating that confirm the robustness of our conclusions. Our results pave the way to an evolutionary rationale for modelling social interactions through game theory with a preferred set of update rules.

Normal response function method for mass and stiffness matrix updating using complex FRFs

NASA Astrophysics Data System (ADS)

Pradhan, S.; Modak, S. V.

2012-10-01

Quite often a structural dynamic finite element model is required to be updated so as to accurately predict the dynamic characteristics like natural frequencies and the mode shapes. Since in many situations undamped natural frequencies and mode shapes need to be predicted, it has generally been the practice in these situations to seek updating of only mass and stiffness matrix so as to obtain a reliable prediction model. Updating using frequency response functions (FRFs) has been one of the widely used approaches for updating, including updating of mass and stiffness matrices. However, the problem with FRF based methods, for updating mass and stiffness matrices, is that these methods are based on use of complex FRFs. Use of complex FRFs to update mass and stiffness matrices is not theoretically correct as complex FRFs are not only affected by these two matrices but also by the damping matrix. Therefore, in situations where updating of only mass and stiffness matrices using FRFs is required, the use of complex FRFs based updating formulation is not fully justified and would lead to inaccurate updated models. This paper addresses this difficulty and proposes an improved FRF based finite element model updating procedure using the concept of normal FRFs. The proposed method is a modified version of the existing response function method that is based on the complex FRFs. The effectiveness of the proposed method is validated through a numerical study of a simple but representative beam structure. The effect of coordinate incompleteness and robustness of method under presence of noise is investigated. The results of updating obtained by the improved method are compared with the existing response function method. The performance of the two approaches is compared for cases of light, medium and heavily damped structures. It is found that the proposed improved method is effective in updating of mass and stiffness matrices in all the cases of complete and incomplete data and with all levels and types of damping.

The GEOS Chemistry Climate Model: Implications of Climate Feedbacks on Ozone Depletion and Recovery

NASA Technical Reports Server (NTRS)

Stolarski, Richard S.; Pawson, Steven; Douglass, Anne R.; Newman, Paul A.; Kawa, S. Randy; Nielsen, J. Eric; Rodriquez, Jose; Strahan, Susan; Oman, Luke; Waugh, Darryn

2008-01-01

The Goddard Earth Observing System Chemistry Climate Model (GEOS CCM) has been developed by combining the atmospheric chemistry and transport modules developed over the years at Goddard and the GEOS general circulation model, also developed at Goddard. The first version of the model was used in the CCMVal intercomparison exercises that contributed to the 2006 WMO/UNEP Ozone Assessment. The second version incorporates the updated version of the GCM (GEOS 5) and will be used for the next round of CCMVal evaluations and the 2010 Ozone Assessment. The third version, now under development, incorporates the combined stratosphere and troposphere chemistry package developed under the Global Modeling Initiative (GMI). We will show comparison to past observations that indicate that we represent the ozone trends over the past 30 years. We will also show the basic temperature, composition, and dynamical structure of the simulations. We will further show projections into the future. We will show results from an ensemble of transient and time-slice simulations, including simulations with fixed 1960 chlorine, simulations with a best guess scenario (Al), and simulations with extremely high chlorine loadings. We will discuss planned extensions of the model to include emission-based boundary conditions for both anthropogenic and biogenic compounds.

USER'S GUIDE TO THE PERSONAL COMPUTER VERSION OF THE BIOGENIC EMISSIONS INVENTORY SYSTEM (PC-BEIS2)

EPA Science Inventory

The document is a user's guide for an updated Personal Computer version of the Biogenic Emissions Inventory System (PC-BEIS2), allowing users to estimate hourly emissions of biogenic volatile organic compounds (BVOCs) and soil nitrogen oxide emissions for any county in the contig...

Price Responsiveness in the AEO2003 NEMS Residential and Commercial Buildings Sector Models

EIA Publications

2003-01-01

This paper describes the demand responses to changes in energy prices in the Annual Energy Outlook 2003 versions of the Residential and Commercial Demand Modules of the National Energy Modeling System (NEMS). It updates a similar paper completed for the Annual Energy Outlook 1999 version of the NEMS.

Engineered materials characterization report, volume 3 - corrosion data and modeling update for viability assessments

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCright, R D

1998-06-30

This Engineered Materials Characterization Report (EMCR), Volume 3, discusses in considerable detail the work of the past 18 months on testing the candidate materials proposed for the waste-package (WP) container and on modeling the performance of those materials in the Yucca Mountain (YM) repository setting This report was prepared as an update of information and serves as one of the supporting documents to the Viability Assessment (VA) of the Yucca Mountain Project. Previous versions of the EMCR have provided a history and background of container-materials selection and evaluation (Volume I), a compilation of physical and mechanical properties for the WPmore » design effort (Volume 2), and corrosion-test data and performance-modeling activities (Volume 3). Because the information in Volumes 1 and 2 is still largely current, those volumes are not being revised. As new information becomes available in the testing and modeling efforts, Volume 3 is periodically updated to include that information.« less

A User''s Guide to the Zwikker-Kosten Transmission Line Code (ZKTL)

NASA Technical Reports Server (NTRS)

Kelly, J. J.; Abu-Khajeel, H.

1997-01-01

This user's guide documents updates to the Zwikker-Kosten Transmission Line Code (ZKTL). This code was developed for analyzing new liner concepts developed to provide increased sound absorption. Contiguous arrays of multi-degree-of-freedom (MDOF) liner elements serve as the model for these liner configurations, and Zwikker and Kosten's theory of sound propagation in channels is used to predict the surface impedance. Transmission matrices for the various liner elements incorporate both analytical and semi-empirical methods. This allows standard matrix techniques to be employed in the code to systematically calculate the composite impedance due to the individual liner elements. The ZKTL code consists of four independent subroutines: 1. Single channel impedance calculation - linear version (SCIC) 2. Single channel impedance calculation - nonlinear version (SCICNL) 3. Multi-channel, multi-segment, multi-layer impedance calculation - linear version (MCMSML) 4. Multi-channel, multi-segment, multi-layer impedance calculation - nonlinear version (MCMSMLNL) Detailed examples, comments, and explanations for each liner impedance computation module are included. Also contained in the guide are depictions of the interactive execution, input files and output files.

Updated recommendations: an assessment of NICE clinical guidelines

PubMed Central

2014-01-01

Background Updating is important to ensure clinical guideline (CG) recommendations remain valid. However, little research has been undertaken in this field. We assessed CGs produced by the National Institute for Health and Care Excellence (NICE) to identify and describe updated recommendations and to investigate potential factors associated with updating. Also, we evaluated the reporting and presentation of recommendation changes. Methods We performed a descriptive analysis of original and updated CGs and recommendations, and an assessment of presentation formats and methods for recording information. We conducted a case-control study, defining cases as original recommendations that were updated (‘new-replaced’ recommendations), and controls as original recommendations that were considered to remain valid (‘not changed’ recommendations). We performed a comparison of main characteristics between cases and controls, and we planned a multiple regression analysis to identify potential predictive factors for updating. Results We included nine updated CGs (1,306 recommendations) and their corresponding original versions (1,106 recommendations). Updated CGs included 812 (62%) recommendations ‘not reviewed’, 368 (28.1%) ‘new’ recommendations, 104 (7.9%) ‘amended’ recommendations, and 25 (1.9%) recommendations reviewed but unchanged. The presentation formats used to indicate the changes in recommendations varied widely across CGs. Changes in ‘amended’, ‘deleted’, and ‘new-replaced’ recommendations (n = 296) were reported infrequently, mostly in appendices. These changes were recorded in 167 (56.4%) recommendations; and were explained in 81 (27.4%) recommendations. We retrieved a total of 7.1% (n = 78) case recommendations (‘new-replaced’) and 2.4% (n = 27) control recommendations (‘not changed’) in original CGs. The updates were mainly from ‘Fertility CG’, about ‘gynaecology, pregnancy and birth’ topic, and ‘treatment’ or ‘prevention’ purposes. We did not perform the multiple regression analysis as originally planned due to the small sample of recommendations retrieved. Conclusion Our study is the first to describe and assess updated CGs and recommendations from a national guideline program. Our results highlight the pressing need to standardise the reporting and presentation of updated recommendations and the research gap about the optimal way to present updates to guideline users. Furthermore, there is a need to investigate updating predictive factors. PMID:24919856

A New More Accurate Calibration for TIMED/GUVI

NASA Astrophysics Data System (ADS)

Schaefer, R. K.; Aiello, J.; Wolven, B. C.; Paxton, L. J.; Romeo, G.; Zhang, Y.

2017-12-01

The Global UltraViolet Imager (GUVI - http://guvi.jhuapl.edu) on NASA's TIMED spacecraft has the longest continuous set of observations of the Earth's ionosphere and thermosphere, spanning more than one solar cycle (2001-2017). As such, it represents an important dataset for understanding the dynamics of the Ionosphere-Thermosphere system. The entire dataset has been reprocessed and released as a new version (13) of GUVI data products. This is a complete re-examination of the calibration elements, including better calibrated radiances, better geolocation, and better background subtraction. Details can be found on the GUVI website: http://guvitimed.jhuapl.edu/guvi-Calib_Prod The radiances (except for the LBH long band) in version 13 are within 10% of the original archival radiances and so most of the derived products are little changed from their original versions. The LBH long band was redefined in on-board instrument color tables on Nov., 2, 2004 to better limit contamination from Nitric Oxide emission but this was not updated in ground processing until now. Version 13 LBH Long has 19% smaller radiances than the old calibrated products for post 11/2/2004 data. GUVI auroral products are the only ones that use LBHL - (LBH long)/(LBH short) is used to gauge the amount of intervening oxygen absorption. We will show several examples of the difference between new and old auroral products. Overall version 13 represents a big improvement in the calibration, geolocation, and background of the GUVI UV data products, allowing for the cleanest UV data for analysis of the ionosphere-thermosphere-aurora. An updated "Using GUVI Data Tutorial" will be available from the GUVI webpage to help you navigate to the data you need. Data products are displayed as daily summary and Google Earth files that can be browsed through the Cesium tool on the GUVI website or the image files can be downloaded and viewed through the Google Earth app. The image below shows gridded 135.6 nm radiances from March 27, 2003 displayed in Google Earth.

Phylogenetic classification of bony fishes.

PubMed

Betancur-R, Ricardo; Wiley, Edward O; Arratia, Gloria; Acero, Arturo; Bailly, Nicolas; Miya, Masaki; Lecointre, Guillaume; Ortí, Guillermo

2017-07-06

Fish classifications, as those of most other taxonomic groups, are being transformed drastically as new molecular phylogenies provide support for natural groups that were unanticipated by previous studies. A brief review of the main criteria used by ichthyologists to define their classifications during the last 50 years, however, reveals slow progress towards using an explicit phylogenetic framework. Instead, the trend has been to rely, in varying degrees, on deep-rooted anatomical concepts and authority, often mixing taxa with explicit phylogenetic support with arbitrary groupings. Two leading sources in ichthyology frequently used for fish classifications (JS Nelson's volumes of Fishes of the World and W. Eschmeyer's Catalog of Fishes) fail to adopt a global phylogenetic framework despite much recent progress made towards the resolution of the fish Tree of Life. The first explicit phylogenetic classification of bony fishes was published in 2013, based on a comprehensive molecular phylogeny ( www.deepfin.org ). We here update the first version of that classification by incorporating the most recent phylogenetic results. The updated classification presented here is based on phylogenies inferred using molecular and genomic data for nearly 2000 fishes. A total of 72 orders (and 79 suborders) are recognized in this version, compared with 66 orders in version 1. The phylogeny resolves placement of 410 families, or ~80% of the total of 514 families of bony fishes currently recognized. The ordinal status of 30 percomorph families included in this study, however, remains uncertain (incertae sedis in the series Carangaria, Ovalentaria, or Eupercaria). Comments to support taxonomic decisions and comparisons with conflicting taxonomic groups proposed by others are presented. We also highlight cases were morphological support exist for the groups being classified. This version of the phylogenetic classification of bony fishes is substantially improved, providing resolution for more taxa than previous versions, based on more densely sampled phylogenetic trees. The classification presented in this study represents, unlike any other, the most up-to-date hypothesis of the Tree of Life of fishes.

Real World Cognitive Multi-Tasking and Problem Solving: A Large Scale Cognitive Architecture Simulation Through High Performance Computing-Project Casie

DTIC Science & Technology

2008-03-01

computational version of the CASIE architecture serves to demonstrate the functionality of our primary theories. However, implementation of several other...following facts. First, based on Theorem 3 and Theorem 5, the objective function is non -increasing under updating rule (6); second, by the criteria for...reassignment in updating rule (7), it is trivial to show that the objective function is non -increasing under updating rule (7). A Unified View to Graph

RESIS-II: An Updated Version of the Original Reservoir Sedimentation Survey Information System (RESIS) Database

USGS Publications Warehouse

Ackerman, Katherine V.; Mixon, David M.; Sundquist, Eric T.; Stallard, Robert F.; Schwarz, Gregory E.; Stewart, David W.

2009-01-01

The Reservoir Sedimentation Survey Information System (RESIS) database, originally compiled by the Soil Conservation Service (now the Natural Resources Conservation Service) in collaboration with the Texas Agricultural Experiment Station, is the most comprehensive compilation of data from reservoir sedimentation surveys throughout the conterminous United States (U.S.). The database is a cumulative historical archive that includes data from as early as 1755 and as late as 1993. The 1,823 reservoirs included in the database range in size from farm ponds to the largest U.S. reservoirs (such as Lake Mead). Results from 6,617 bathymetric surveys are available in the database. This Data Series provides an improved version of the original RESIS database, termed RESIS-II, and a report describing RESIS-II. The RESIS-II relational database is stored in Microsoft Access and includes more precise location coordinates for most of the reservoirs than the original database but excludes information on reservoir ownership. RESIS-II is anticipated to be a template for further improvements in the database.

Rubbertown NGEM Demonstration Project?Community Update Meeting 2, July 25, 2017

EPA Science Inventory

This is a slide deck for part of a community webinar held by LMAPCD to provide an update on the project. The slides will be delivered by team lead E. Thoma remotely by webinar. A draft version of the QAPP for the project will be provided to the community as part of this communi...

Complex Burn Region Module (CBRM) update

NASA Technical Reports Server (NTRS)

Adams, Carl L.; Jenkins, Billy

1991-01-01

Presented here is a Complex Burn Region Module (CBRM) update for the Solid Rocket Internal Ballistics Module (SRIBM) Program for the Advanced Solid Rocket Motor (ASRM) design/performance assessments. The goal was to develop an improved version of the solid rocket internal ballistics module program that contains a diversified complex region model for motor grain design, performance prediction, and evaluation.

Selected text of Atomic Energy Act, Executive Orders and other laws of general interest to safeguards and security executives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cadwell, J.J.; Ruger, C.J.

1995-12-01

This document is one of a three report set, BNL 52201 contains detailed information for use by executives. BNL 52202 is titled, U.S. Statutes of General Interest to Safeguards and Security Officers, and contains less detail than BNL 52201. It is intended for use by officers. BNL 52203 is titled, U.S.Statutes for Enforcement by Security Inspectors, and only contains statutes to be applied by uniformed security inspectors. These are a newly updated version of a set of documents of similar titles published in September 1988, which were an updated version of an original set of documents published in November 1983.

ChAMP: updated methylation analysis pipeline for Illumina BeadChips.

PubMed

Tian, Yuan; Morris, Tiffany J; Webster, Amy P; Yang, Zhen; Beck, Stephan; Feber, Andrew; Teschendorff, Andrew E

2017-12-15

The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for high-throughput DNA methylation analysis, effectively doubling the coverage compared to the older 450 K array. Here we present a significantly updated and improved version of the Bioconductor package ChAMP, which can be used to analyze EPIC and 450k data. Many enhanced functionalities have been added, including correction for cell-type heterogeneity, network analysis and a series of interactive graphical user interfaces. ChAMP is a BioC package available from https://bioconductor.org/packages/release/bioc/html/ChAMP.html. a.teschendorff@ucl.ac.uk or s.beck@ucl.ac.uk or a.feber@ucl.ac.uk. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

Wilderness Medical Society practice guidelines for the prevention and treatment of lightning injuries: 2014 update.

PubMed

Davis, Chris; Engeln, Anna; Johnson, Eric L; McIntosh, Scott E; Zafren, Ken; Islas, Arthur A; McStay, Christopher; Smith, William R; Cushing, Tracy

2014-12-01

To provide guidance to clinicians about best practices, the Wilderness Medical Society (WMS) convened an expert panel to develop evidence-based guidelines for the treatment and prevention of lightning injuries. These guidelines include a review of the epidemiology of lightning and recommendations for the prevention of lightning strikes, along with treatment recommendations organized by organ system. Recommendations are graded on the basis of the quality of supporting evidence according to criteria put forth by the American College of Chest Physicians. This is an updated version of the original WMS Practice Guidelines for Prevention and Treatment of Lightning Injuries published in Wilderness & Environmental Medicine 2012;23(3):260-269. Copyright © 2014 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

Sandia Advanced MEMS Design Tools, Version 2.2.5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yarberry, Victor; Allen, James; Lantz, Jeffery

2010-01-19

The Sandia National Laboratories Advanced MEMS Design Tools, Version 2.2.5, is a collection of menus, prototype drawings, and executables that provide significant productivity enhancements when using AutoCAD to design MEMS components. This release is designed for AutoCAD 2000i, 2002, or 2004 and is supported under Windows NT 4.0, Windows 2000, or XP. SUMMiT V (Sandia Ultra planar Multi level MEMS Technology) is a 5 level surface micromachine fabrication technology, which customers internal and external to Sandia can access to fabricate prototype MEMS devices. This CD contains an integrated set of electronic files that: a) Describe the SUMMiT V fabrication processmore » b) Facilitate the process of designing MEMS with the SUMMiT process (prototype file, Design Rule Checker, Standard Parts Library) New features in this version: AutoCAD 2004 support has been added. SafeExplode ? a new feature that explodes blocks without affecting polylines (avoids exploding polylines into objects that are ignored by the DRC and Visualization tools). Layer control menu ? a pull-down menu for selecting layers to isolate, freeze, or thaw. Updated tools: A check has been added to catch invalid block names. DRC features: Added username/password validation, added a method to update the user?s password. SNL_DRC_WIDTH ? a value to control the width of the DRC error lines. SNL_BIAS_VALUE ? a value use to offset selected geometry SNL_PROCESS_NAME ? a value to specify the process name Documentation changes: The documentation has been updated to include the new features. While there exist some files on the CD that are used in conjunction with software package AutoCAD, these files are not intended for use independent of the CD. Note that the customer must purchase his/her own copy of AutoCAD to use with these files.« less

Documentation for the machine-readable version of the Henry Draper Catalogue (edition 1985)

NASA Technical Reports Server (NTRS)

Roman, N. G.; Warren, W. H., Jr.

1985-01-01

An updated, corrected and extended machine-readable version of the catalog is described. Published and unpublished errors discovered in the previous version was corrected; letters indicating supplemental stars in the BD have been moved to a new byte to distinguish them from double-star components; and the machine readable portion of The Henry Draper Extension (HDE) (HA 100) was converted to the same format as the main catalog, with additional data added as necessary.

Improving Earth Science Metadata: Modernizing ncISO

NASA Astrophysics Data System (ADS)

O'Brien, K.; Schweitzer, R.; Neufeld, D.; Burger, E. F.; Signell, R. P.; Arms, S. C.; Wilcox, K.

2016-12-01

ncISO is a package of tools developed at NOAA's National Center for Environmental Information (NCEI) that facilitates the generation of ISO 19115-2 metadata from NetCDF data sources. The tool currently exists in two iterations: a command line utility and a web-accessible service within the THREDDS Data Server (TDS). Several projects, including NOAA's Unified Access Framework (UAF), depend upon ncISO to generate the ISO-compliant metadata from their data holdings and use the resulting information to populate discovery tools such as NCEI's ESRI Geoportal and NOAA's data.noaa.gov CKAN system. In addition to generating ISO 19115-2 metadata, the tool calculates a rubric score based on how well the dataset follows the Attribute Conventions for Dataset Discovery (ACDD). The result of this rubric calculation, along with information about what has been included and what is missing is displayed in an HTML document generated by the ncISO software package. Recently ncISO has fallen behind in terms of supporting updates to conventions such updates to the ACDD. With the blessing of the original programmer, NOAA's UAF has been working to modernize the ncISO software base. In addition to upgrading ncISO to utilize version1.3 of the ACDD, we have been working with partners at Unidata and IOOS to unify the tool's code base. In essence, we are merging the command line capabilities into the same software that will now be used by the TDS service, allowing easier updates when conventions such as ACDD are updated in the future. In this presentation, we will discuss the work the UAF project has done to support updated conventions within ncISO, as well as describe how the updated tool is helping to improve metadata throughout the earth and ocean sciences.

DFN Modeling for the Safety Case of the Final Disposal of Spent Nuclear Fuel in Olkiluoto, Finland

NASA Astrophysics Data System (ADS)

Vanhanarkaus, O.

2017-12-01

Olkiluoto Island is a site in SW Finland chosen to host a deep geological repository for high-level nuclear waste generated by nuclear power plants of power companies TVO and Fortum. Posiva, a nuclear waste management organization, submitted a construction license application for the Olkiluoto repository to the Finnish government in 2012. A key component of the license application was an integrated geological, hydrological and biological description of the Olkiluoto site. After the safety case was reviewed in 2015 by the Radiation and Nuclear Safety Authority in Finland, Posiva was granted a construction license. Posiva is now preparing an updated safety case for the operating license application to be submitted in 2022, and an update of the discrete fracture network (DFN) model used for site characterization is part of that. The first step describing and modelling the network of fractures in the Olkiluoto bedrock was DFN model version 1 (2009), which presented an initial understanding of the relationships between rock fracturing and geology at the site and identified the important primary controls on fracturing. DFN model version 2 (2012) utilized new subsurface data from additional drillholes, tunnels and excavated underground facilities in ONKALO to better understand spatial variability of the geological controls on geological and hydrogeological fracture properties. DFN version 2 connected fracture geometric and hydraulic properties to distinct tectonic domains and to larger-scale hydraulically conductive fault zones. In the version 2 DFN model, geological and hydrogeological models were developed along separate parallel tracks. The version 3 (2017) DFN model for the Olkiluoto site integrates geological and hydrogeological elements into a single consistent model used for geological, rock mechanical, hydrogeological and hydrogeochemical studies. New elements in the version 3 DFN model include a stochastic description of fractures within Brittle Fault Zones (BFZ), integration of geological and hydrostructural interpretations of BFZ, greater use of 3D geological models to better constrain the spatial variability of fracturing and fractures using hydromechanical principles to account for material behavior and in-situ stresses.

Records and Reports Guide

DTIC Science & Technology

2017-07-01

2017 to incorporate revised factors from the DEOMI Organizational Climate Survey (DEOCS) version 4.0 to version 4.1. This update primarily effects...begins with a survey , such as the DEOMI Organizational Climate Survey (DEOCS). Once survey themes, indicators, or concerns are identified, other...climate assessment to verify indicators and concerns identified through other assessment methods ( surveys , observations, and interviews

Student Attitudes toward Web-Enhanced and Web-Based Versions of a Learning Tools Course

ERIC Educational Resources Information Center

Davidson-Shivers, Gayle V.; Wimberg, Jane E.; Jackson, M. Katherine

2004-01-01

The presentation describes the revisions to a course and the resulting student attitudes and learning. Learning Tools was revised in 2003 from oncampus only to both oncampus and online delivery. Revisions were made by standardizing the two versions, updating the technology applications presented, and modifying the instructional strategies used.…

Annual Report: Carbon Capture Simulation Initiative (CCSI) (30 September 2013)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, David C.; Syamlal, Madhava; Cottrell, Roger

2013-09-30

The Carbon Capture Simulation Initiative (CCSI) is a partnership among national laboratories, industry and academic institutions that is developing and deploying state-of-the-art computational modeling and simulation tools to accelerate the commercialization of carbon capture technologies from discovery to development, demonstration, and ultimately the widespread deployment to hundreds of power plants. The CCSI Toolset will provide end users in industry with a comprehensive, integrated suite of scientifically validated models, with uncertainty quantification (UQ), optimization, risk analysis and decision making capabilities. The CCSI Toolset incorporates commercial and open-source software currently in use by industry and is also developing new software tools asmore » necessary to fill technology gaps identified during execution of the project. Ultimately, the CCSI Toolset will (1) enable promising concepts to be more quickly identified through rapid computational screening of devices and processes; (2) reduce the time to design and troubleshoot new devices and processes; (3) quantify the technical risk in taking technology from laboratory-scale to commercial-scale; and (4) stabilize deployment costs more quickly by replacing some of the physical operational tests with virtual power plant simulations. CCSI is led by the National Energy Technology Laboratory (NETL) and leverages the Department of Energy (DOE) national laboratories’ core strengths in modeling and simulation, bringing together the best capabilities at NETL, Los Alamos National Laboratory (LANL), Lawrence Berkeley National Laboratory (LBNL), Lawrence Livermore National Laboratory (LLNL), and Pacific Northwest National Laboratory (PNNL). The CCSI’s industrial partners provide representation from the power generation industry, equipment manufacturers, technology providers and engineering and construction firms. The CCSI’s academic participants (Carnegie Mellon University, Princeton University, West Virginia University, Boston University and the University of Texas at Austin) bring unparalleled expertise in multiphase flow reactors, combustion, process synthesis and optimization, planning and scheduling, and process control techniques for energy processes. During Fiscal Year (FY) 13, CCSI announced the initial release of its first set of computational tools and models during the October 2012 meeting of its Industry Advisory Board. This initial release led to five companies licensing the CCSI Toolset under a Test and Evaluation Agreement this year. By the end of FY13, the CCSI Technical Team had completed development of an updated suite of computational tools and models. The list below summarizes the new and enhanced toolset components that were released following comprehensive testing during October 2013. 1. FOQUS. Framework for Optimization and Quantification of Uncertainty and Sensitivity. Package includes: FOQUS Graphic User Interface (GUI), simulation-based optimization engine, Turbine Client, and heat integration capabilities. There is also an updated simulation interface and new configuration GUI for connecting Aspen Plus or Aspen Custom Modeler (ACM) simulations to FOQUS and the Turbine Science Gateway. 2. A new MFIX-based Computational Fluid Dynamics (CFD) model to predict particle attrition. 3. A new dynamic reduced model (RM) builder, which generates computationally efficient RMs of the behavior of a dynamic system. 4. A completely re-written version of the algebraic surrogate model builder for optimization (ALAMO). The new version is several orders of magnitude faster than the initial release and eliminates the MATLAB dependency. 5. A new suite of high resolution filtered models for the hydrodynamics associated with horizontal cylindrical objects in a flow path. 6. The new Turbine Science Gateway (Cluster), which supports FOQUS for running multiple simulations for optimization or UQ using a local computer or cluster. 7. A new statistical tool (BSS-ANOVA-UQ) for calibration and validation of CFD models. 8. A new basic data submodel in Aspen Plus format for a representative high viscosity capture solvent, 2-MPZ system. 9. An updated RM tool for CFD (REVEAL) that can create a RM from MFIX. A new lightweight, stand-alone version will be available in late 2013. 10. An updated RM integration tool to convert the RM from REVEAL into a CAPE-OPEN or ACM model for use in a process simulator. 11. An updated suite of unified steady-state and dynamic process models for solid sorbent carbon capture included bubbling fluidized bed and moving bed reactors. 12. An updated and unified set of compressor models including steady-state design point model and dynamic model with surge detection. 13. A new framework for the synthesis and optimization of coal oxycombustion power plants using advanced optimization algorithms. This release focuses on modeling and optimization of a cryogenic air separation unit (ASU). 14. A new technical risk model in spreadsheet format. 15. An updated version of the sorbent kinetic/equilibrium model for parameter estimation for the 1st generation sorbent model. 16. An updated process synthesis superstructure model to determine optimal process configurations utilizing surrogate models from ALAMO for adsorption and regeneration in a solid sorbent process. 17. Validation models for NETL Carbon Capture Unit utilizing sorbent AX. Additional validation models will be available for sorbent 32D in 2014. 18. An updated hollow fiber membrane model and system example for carbon capture. 19. An updated reference power plant model in Thermoflex that includes additional steam extraction and reinjection points to enable heat integration module. 20. An updated financial risk model in spreadsheet format.« less

Fleischner Society: glossary of terms for thoracic imaging.

PubMed

Hansell, David M; Bankier, Alexander A; MacMahon, Heber; McLoud, Theresa C; Müller, Nestor L; Remy, Jacques

2008-03-01

Members of the Fleischner Society compiled a glossary of terms for thoracic imaging that replaces previous glossaries published in 1984 and 1996 for thoracic radiography and computed tomography (CT), respectively. The need to update the previous versions came from the recognition that new words have emerged, others have become obsolete, and the meaning of some terms has changed. Brief descriptions of some diseases are included, and pictorial examples (chest radiographs and CT scans) are provided for the majority of terms. (c) RSNA, 2008.

The Totality App — General Lessons and Future Eclipses

NASA Astrophysics Data System (ADS)

Bennett, Jeffrey

2018-06-01

With the excitement around the 2017 eclipse, I worked with an app development company to create the Totality app, which featured eclipse predictions from the code of Xavier Jubier. We have since updated the app for future eclipses, including a Spanish version given the upcoming eclipses in Chile/Argentina. I will briefly discuss the current app, the process through which we developed it, and relevant lessons learned along the way that may be useful to others interested in developing apps for astronomy education.

Calibration of the Total and Static Pressure Transducers in the DSTO Transonic Wind Tunnel

DTIC Science & Technology

2010-08-01

handled by the ActiveX control MSCOMM32.OCX which is not part of the Microsoft Windows operating system. It is, however, included as part of the...implemented new measures to register ActiveX controls in its Windows suite of operating systems, which has made the above file obsolete and it could no...longer be used if the Windows operating system were updated. If this is the case, then the new version of ActiveX control files can be installed using

150 years of Sigmund Freud: What would Freud have said about the obesity epidemic?

PubMed

Bornstein, S R; Wong, M-L; Licinio, J

2006-12-01

The 150th birthday of Sigmund Freud has triggered widespread interest and media coverage on his unique contribution and impact on society. Recent evidence from neuroscience and advanced imaging technology has provided support for some of his major concepts including the unconscious and the key role of early life events. In this perspective, we attempt to write on his behalf an updated version of a Freudian way of thinking focused on the current high rates of obesity and depression.

78 FR 26437 - Medicare Program; Prospective Payment System and Consolidated Billing for Skilled Nursing...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-06

...This proposed rule would update the payment rates used under the prospective payment system (PPS) for skilled nursing facilities (SNFs) for fiscal year (FY) 2014, would revise and rebase the SNF market basket, and would make certain technical and conforming revisions in the regulations text. This proposed rule also includes a proposed policy for reporting the SNF market basket forecast error correction in certain limited circumstances and a proposed new item for the Minimum Data Set (MDS), Version 3.0.

A New Architecture for Extending the Capabilities of the Copernicus Trajectory Optimization Program

NASA Technical Reports Server (NTRS)

Williams, Jacob

2015-01-01

This paper describes a new plugin architecture developed for the Copernicus spacecraft trajectory optimization program. Details of the software architecture design and development are described, as well as examples of how the capability can be used to extend the tool in order to expand the type of trajectory optimization problems that can be solved. The inclusion of plugins is a significant update to Copernicus, allowing user-created algorithms to be incorporated into the tool for the first time. The initial version of the new capability was released to the Copernicus user community with version 4.1 in March 2015, and additional refinements and improvements were included in the recent 4.2 release. It is proving quite useful, enabling Copernicus to solve problems that it was not able to solve before.

Cutting through the Hype: The Essential Guide to School Reform. Revised, Expanded, and Updated Edition

ERIC Educational Resources Information Center

David, Jane L.; Cuban, Larry

2010-01-01

"Cutting Through the Hype: The Essential Guide to School Reform" is a revised, expanded, and updated version of the classic work by Jane L. David and Larry Cuban. It offers balanced analyses of 23 currently popular school reform strategies, from teacher performance pay and putting mayors in charge to turnaround schools and data-driven instruction.…

National Drug Control Strategy. Update

ERIC Educational Resources Information Center

Office of National Drug Control Policy, 2005

2005-01-01

The first National Drug Control Strategy set ambitious two and five-year performance based goals: (1) to lower the rate of drug use by 10 percent over 2 years among both youth and adults; and (2) to lower the rate by 25 percent over 5 years. The chapters in this updated version are keyed to the strategies three priorities: (1) Stopping Use Before…

Spanish consensus on the use of natalizumab (Tysabri®)-2013.

PubMed

Fernández, O; García-Merino, J A; Arroyo, R; Álvarez-Cermeño, J C; Izquierdo, G; Saiz, A; Olascoaga, J; Rodríguez-Antigüedad, A; Prieto, J M; Oreja-Guevara, C; Hernández, M A; Moral, E; Meca, J; Montalbán, X

2015-06-01

Natalizumab treatment has been shown to be very efficacious in clinical trials and very effective in clinical practice in patients with relapsing-remitting multiple sclerosis, by reducing relapses, slowing disease progression, and improving magnetic resonance imaging patterns. However, the drug has also been associated with a risk of progressive multifocal leukoencephalopathy (PML). The first consensus statement on natalizumab use, published in 2011, has been updated to include new data on diagnostic procedures, monitoring for patients undergoing treatment, PML management, and other topics of interest including the management of patients discontinuing natalizumab. This updated version followed the method used in the first consensus. A group of Spanish experts in multiple sclerosis (the authors of the present document) reviewed all currently available literature on natalizumab and identified the relevant topics would need updating based on their clinical experience. The initial draft passed through review cycles until the final version was completed. Studies in clinical practice have demonstrated that changing to natalizumab is more effective than switching between immunomodulators. They favour early treatment with natalizumab rather than using natalizumab in a later stage as a rescue therapy. Although the drug is very effective, its potential adverse effects need to be considered, with particular attention to the patient's likelihood of developing PML. The neurologist should carefully explain the risks and benefits of the treatment, comparing them to the risks of multiple sclerosis in terms the patient can understand. Before treatment is started, laboratory tests and magnetic resonance images should be available to permit proper follow-up. The risk of PML should be stratified as high, medium, or low according to presence or absence of anti-JC virus antibodies, history of immunosuppressive therapy, and treatment duration. Although the presence of anti-JC virus antibodies is a significant finding, it should not be considered an absolute contraindication for natalizumab. This update provides general recommendations, but neurologists must use their clinical expertise to provide personalised follow-up for each patient. Copyright © 2013 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.

PlantTFDB 3.0: a portal for the functional and evolutionary study of plant transcription factors

PubMed Central

Jin, Jinpu; Zhang, He; Kong, Lei; Gao, Ge; Luo, Jingchu

2014-01-01

With the aim to provide a resource for functional and evolutionary study of plant transcription factors (TFs), we updated the plant TF database PlantTFDB to version 3.0 (http://planttfdb.cbi.pku.edu.cn). After refining the TF classification pipeline, we systematically identified 129 288 TFs from 83 species, of which 67 species have genome sequences, covering main lineages of green plants. Besides the abundant annotation provided in the previous version, we generated more annotations for identified TFs, including expression, regulation, interaction, conserved elements, phenotype information, expert-curated descriptions derived from UniProt, TAIR and NCBI GeneRIF, as well as references to provide clues for functional studies of TFs. To help identify evolutionary relationship among identified TFs, we assigned 69 450 TFs into 3924 orthologous groups, and constructed 9217 phylogenetic trees for TFs within the same families or same orthologous groups, respectively. In addition, we set up a TF prediction server in this version for users to identify TFs from their own sequences. PMID:24174544

The development of MML (Medical Markup Language) version 3.0 as a medical document exchange format for HL7 messages.

PubMed

Guo, Jinqiu; Takada, Akira; Tanaka, Koji; Sato, Junzo; Suzuki, Muneou; Suzuki, Toshiaki; Nakashima, Yusei; Araki, Kenji; Yoshihara, Hiroyuki

2004-12-01

Medical Markup Language (MML), as a set of standards, has been developed over the last 8 years to allow the exchange of medical data between different medical information providers. MML Version 2.21 used XML as a metalanguage and was announced in 1999. In 2001, MML was updated to Version 2.3, which contained 12 modules. The latest version--Version 3.0--is based on the HL7 Clinical Document Architecture (CDA). During the development of this new version, the structure of MML Version 2.3 was analyzed, subdivided into several categories, and redefined so the information defined in MML could be described in HL7 CDA Level One. As a result of this development, it has become possible to exchange MML Version 3.0 medical documents via HL7 messages.

TSARINA: A Computer Model for Assessing Conventional and Chemical Attacks on Airbases

DTIC Science & Technology

1990-09-01

IV, and has been updated to FORTRAN 77; it has been adapted to various computer systems, as was the widely used AIDA model and the previous versions of...conventional and chemical attacks on sortie generation. In the first version of TSARINA [1 2], several key additions were made to the AIDA model so that (1...various on-base resources, in addition to the estimates of hits and facility damage that are generated by the original AIDA model . The second version

Connectionist Models: Proceedings of the Summer School Held in San Diego, California on 1990

DTIC Science & Technology

1990-01-01

modes: control network continues activation spreading based There is the sequential version and the parallel version on the actual inputs instead of...ent). 2. Execute all motoric actions based on activations of r a ent.The parallel version of the algorithm is local in time, units in A. Update the...a- movements that help o recognize an entering person.) tions like ’move focus left’, ’rotate focus’ are based on the activations of the C’s output

Tool for Analysis and Reduction of Scientific Data

NASA Technical Reports Server (NTRS)

James, Mark

2006-01-01

The Automated Scheduling and Planning Environment (ASPEN) computer program has been updated to version 3.0. ASPEN as a whole (up to version 2.0) has been summarized, and selected aspects of ASPEN have been discussed in several previous NASA Tech Briefs articles. Restated briefly, ASPEN is a modular, reconfigurable, application software framework for solving batch problems that involve reasoning about time, activities, states, and resources. Applications of ASPEN can include planning spacecraft missions, scheduling of personnel, and managing supply chains, inventories, and production lines. ASPEN 3.0 can be customized for a wide range of applications and for a variety of computing environments that include various central processing units and randomaccess memories. Domain-specific reasoning modules (e.g., modules for determining orbits for spacecraft) can easily be plugged into ASPEN 3.0. Improvements over other, similar software that have been incorporated into ASPEN 3.0 include a provision for more expressive time-line values, new parsing capabilities afforded by an ASPEN language based on Extensible Markup Language, improved search capabilities, and improved interfaces to other, utility-type software (notably including MATLAB).

Earth observing system. Output data products and input requirements, version 2.0. Volume 1: Instrument data product characteristics

NASA Technical Reports Server (NTRS)

Lu, Yun-Chi; Chang, Hyo Duck; Krupp, Brian; Kumar, Ravindra; Swaroop, Anand

1992-01-01

Information on Earth Observing System (EOS) output data products and input data requirements that has been compiled by the Science Processing Support Office (SPSO) at GSFC is presented. Since Version 1.0 of the SPSO Report was released in August 1991, there have been significant changes in the EOS program. In anticipation of a likely budget cut for the EOS Project, NASA HQ restructured the EOS program. An initial program consisting of two large platforms was replaced by plans for multiple, smaller platforms, and some EOS instruments were either deselected or descoped. Updated payload information reflecting the restructured EOS program superseding the August 1991 version of the SPSO report is included. This report has been expanded to cover information on non-EOS data products, and consists of three volumes (Volumes 1, 2, and 3). Volume 1 provides information on instrument outputs and input requirements. Volume 2 is devoted to Interdisciplinary Science (IDS) outputs and input requirements, including the 'best' and 'alternative' match analysis. Volume 3 provides information about retrieval algorithms, non-EOS input requirements of instrument teams and IDS investigators, and availability of non-EOS data products at seven primary Distributed Active Archive Centers (DAAC's).

An Update of the Bodeker Scientific Vertically Resolved, Global, Gap-Free Ozone Database

NASA Astrophysics Data System (ADS)

Kremser, S.; Bodeker, G. E.; Lewis, J.; Hassler, B.

2016-12-01

High vertical resolution ozone measurements from multiple satellite-based instruments have been merged with measurements from the global ozonesonde network to calculate monthly mean ozone values in 5º latitude zones. Ozone number densities and ozone mixing ratios are provided on 70 altitude levels (1 to 70 km) and on 70 pressure levels spaced approximately 1 km apart (878.4 hPa to 0.046 hPa). These data are sparse and do not cover the entire globe or altitude range. To provide a gap-free database, a least squares regression model is fitted to these data and then evaluated globally. By applying a single fit at each level, and using the approach of allowing the regression fits to change only slightly from one level to the next, the regression is less sensitive to measurement anomalies at individual stations or to individual satellite-based instruments. Particular attention is paid to ensuring that the low ozone abundances in the polar regions are captured. This presentation reports on updates to an earlier version of the vertically resolved ozone database, including the incorporation of new ozone measurements and new techniques for combining the data. Compared to previous versions of the database, particular attention is paid to avoiding spatial and temporal sampling biases and tracing uncertainties through to the final product. This updated database, developed within the New Zealand Deep South National Science Challenge, is suitable for assessing ozone fields from chemistry-climate model simulations or for providing the ozone boundary conditions for global climate model simulations that do not treat stratospheric chemistry interactively.

TOUGH3 v1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

PAU, GEORGE; JUNG, YOOJIN; FINSTERLE, STEFAN

2016-09-14

TOUGH3 V1.0 capabilities to simulate multi-dimensional, multi-phase, multi-component, non-isothermal flow and transport in fractured porous media, with applications geosciences and reservoir engineering and other application areas. TOUGH3 V1.0 supports a number of different combinations of fluids and components (updated equation-of-state (EOS) modules from previous versions of TOUGH, including EOS1, EOS2, EOS3, EOS4, EOS5, EOS7, EOS7R, EOS7C, EOS7CA, EOS8, EOS9, EWASG, TMVOC, ECO2N, and ECO2M). This upgrade includes (a) expanded list of updated equation-of-state (EOS) modules, (b) new hysteresis models, (c) new implementation of parallel and solver functionalities, (d) new linear solver options based on PETSc libraries, (e) new automatic buildmore » system that automatically downloads and builds third-party libraries and TOUGH3, (f) new printout in CSV format, (g) dynamic memory allocation, (h) various user features, and (i) bug fixes.« less

SOLID WASTE INTEGRATED FORECAST TECHNICAL (SWIFT) REPORT FY2005 THRU FY2035 2005.0 VOLUME 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

BARCOT, R.A.

This report provides up-to-date life cycle information about the radioactive solid waste expected to be managed by Hanford's Waste Management (WM) Project from onsite and offsite generators. It includes: (1) an overview of Hanford-wide solid waste to be managed by the WM Project; (2) multi-level and waste class-specific estimates; (3) background information on waste sources; and (4) comparisons to previous forecasts and other national data sources. The focus of this report is low-level waste (LLW), mixed low-level waste (MLLW), and transuranic waste, both non-mixed and mixed (TRU(M)). Some details on hazardous waste are also provided, however, this information is notmore » considered comprehensive. This report includes data requested in December, 2004 with updates through March 31,2005. The data represent a life cycle forecast covering all reported activities from FY2005 through the end of each program's life cycle and are an update of the previous FY2004.1 data version.« less

PCoM-DB Update: A Protein Co-Migration Database for Photosynthetic Organisms.

PubMed

Takabayashi, Atsushi; Takabayashi, Saeka; Takahashi, Kaori; Watanabe, Mai; Uchida, Hiroko; Murakami, Akio; Fujita, Tomomichi; Ikeuchi, Masahiko; Tanaka, Ayumi

2017-01-01

The identification of protein complexes is important for the understanding of protein structure and function and the regulation of cellular processes. We used blue-native PAGE and tandem mass spectrometry to identify protein complexes systematically, and built a web database, the protein co-migration database (PCoM-DB, http://pcomdb.lowtem.hokudai.ac.jp/proteins/top), to provide prediction tools for protein complexes. PCoM-DB provides migration profiles for any given protein of interest, and allows users to compare them with migration profiles of other proteins, showing the oligomeric states of proteins and thus identifying potential interaction partners. The initial version of PCoM-DB (launched in January 2013) included protein complex data for Synechocystis whole cells and Arabidopsis thaliana thylakoid membranes. Here we report PCoM-DB version 2.0, which includes new data sets and analytical tools. Additional data are included from whole cells of the pelagic marine picocyanobacterium Prochlorococcus marinus, the thermophilic cyanobacterium Thermosynechococcus elongatus, the unicellular green alga Chlamydomonas reinhardtii and the bryophyte Physcomitrella patens. The Arabidopsis protein data now include data for intact mitochondria, intact chloroplasts, chloroplast stroma and chloroplast envelopes. The new tools comprise a multiple-protein search form and a heat map viewer for protein migration profiles. Users can compare migration profiles of a protein of interest among different organelles or compare migration profiles among different proteins within the same sample. For Arabidopsis proteins, users can compare migration profiles of a protein of interest with putative homologous proteins from non-Arabidopsis organisms. The updated PCoM-DB will help researchers find novel protein complexes and estimate their evolutionary changes in the green lineage. © The Author 2017. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Guideline on terminology and definitions of updating clinical guidelines: The Updating Glossary.

PubMed

Martínez García, Laura; Pardo-Hernández, Hector; Sanabria, Andrea Juliana; Alonso-Coello, Pablo; Penman, Katrina; McFarlane, Emma

2018-03-01

The Guidelines International Network (G-I-N) Updating Guidelines Working Group launched an initiative to develop a glossary (the Updating Glossary) with domains, terms, definitions, and synonyms related to updating of clinical guidelines (CGs). The steering committee developed an initial list of domains, terms, definitions, and synonyms through brainstorming and discussion. The panel members participated in three rounds of feedback to discuss, refine, and clarify the proposed terms, definitions, and synonyms. Finally, the panel members were surveyed to assess their level of agreement regarding the glossary. Eighteen terms were identified and defined: (1) continuous updating, (2) decision to update, (3) fixed updating, (4) full updating, (5) impact of the new evidence, (6) partial updating, (7) prioritization process, (8) reporting process, (9) signal for an update, (10) surveillance process, (11) time of validity, (12) timeframe, (13) tools and resources, (14) up to date, (15) update cycle, (16) update unit, (17) updated version, and (18) updating strategy. Consensus was reached for all terms, definitions, and synonyms (median agreement scores ≥ 6); except for one term. The G-I-N Updating Guidelines Working Group assembled the Updating Glossary to facilitate and improve the knowledge exchange among CGs developers, researchers, and users. Copyright © 2017 Elsevier Inc. All rights reserved.

An update to the Surface Ocean CO2 Atlas (SOCAT version 2)

NASA Astrophysics Data System (ADS)

Bakker, D. C. E.; Pfeil, B.; Smith, K.; Hankin, S.; Olsen, A.; Alin, S. R.; Cosca, C.; Harasawa, S.; Kozyr, A.; Nojiri, Y.; O'Brien, K. M.; Schuster, U.; Telszewski, M.; Tilbrook, B.; Wada, C.; Akl, J.; Barbero, L.; Bates, N.; Boutin, J.; Cai, W.-J.; Castle, R. D.; Chavez, F. P.; Chen, L.; Chierici, M.; Currie, K.; de Baar, H. J. W.; Evans, W.; Feely, R. A.; Fransson, A.; Gao, Z.; Hales, B.; Hardman-Mountford, N.; Hoppema, M.; Huang, W.-J.; Hunt, C. W.; Huss, B.; Ichikawa, T.; Johannessen, T.; Jones, E. M.; Jones, S. D.; Jutterström, S.; Kitidis, V.; Körtzinger, A.; Landschtzer, P.; Lauvset, S. K.; Lefèvre, N.; Manke, A. B.; Mathis, J. T.; Merlivat, L.; Metzl, N.; Murata, A.; Newberger, T.; Ono, T.; Park, G.-H.; Paterson, K.; Pierrot, D.; Ríos, A. F.; Sabine, C. L.; Saito, S.; Salisbury, J.; Sarma, V. V. S. S.; Schlitzer, R.; Sieger, R.; Skjelvan, I.; Steinhoff, T.; Sullivan, K.; Sun, H.; Sutton, A. J.; Suzuki, T.; Sweeney, C.; Takahashi, T.; Tjiputra, J.; Tsurushima, N.; van Heuven, S. M. A. C.; Vandemark, D.; Vlahos, P.; Wallace, D. W. R.; Wanninkhof, R.; Watson, A. J.

2013-08-01

The Surface Ocean CO2 Atlas (SOCAT) is an effort by the international marine carbon research community. It aims to improve access to carbon dioxide measurements in the surface oceans by regular releases of quality controlled and fully documented synthesis and gridded fCO2 (fugacity of carbon dioxide) products. SOCAT version 2 presented here extends the data set for the global oceans and coastal seas by four years and has 10.1 million surface water fCO2 values from 2660 cruises between 1968 and 2011. The procedures for creating version 2 have been comparable to those for version 1. The SOCAT website (http://www.socat.info/) provides access to the individual cruise data files, as well as to the synthesis and gridded data products. Interactive online tools allow visitors to explore the richness of the data. Scientific users can also retrieve the data as downloadable files or via Ocean Data View. Version 2 enables carbon specialists to expand their studies until 2011. Applications of SOCAT include process studies, quantification of the ocean carbon sink and its spatial, seasonal, year-to-year and longer-term variation, as well as initialisation or validation of ocean carbon models and coupled-climate carbon models.

ALSSAT Version 6.0

NASA Technical Reports Server (NTRS)

Yeh, Hue-Hsia; Brown, Cheryl; Jeng, Frank

2012-01-01

Advanced Life Support Sizing Analysis Tool (ALSSAT) at the time of this reporting has been updated to version 6.0. A previous version was described in Tool for Sizing Analysis of the Advanced Life Support System (MSC- 23506), NASA Tech Briefs, Vol. 29, No. 12 (December 2005), page 43. To recapitulate: ALSSAT is a computer program for sizing and analyzing designs of environmental-control and life-support systems for spacecraft and surface habitats to be involved in exploration of Mars and the Moon. Of particular interest for analysis by ALSSAT are conceptual designs of advanced life-support (ALS) subsystems that utilize physicochemical and biological processes to recycle air and water and process human wastes to reduce the need of resource resupply. ALSSAT is a means of investigating combinations of such subsystems technologies featuring various alternative conceptual designs and thereby assisting in determining which combination is most cost-effective. ALSSAT version 6.0 has been improved over previous versions in several respects, including the following additions: an interface for reading sizing data from an ALS database, computational models of a redundant regenerative CO2 and Moisture Removal Amine Swing Beds (CAMRAS) for CO2 removal, upgrade of the Temperature & Humidity Control's Common Cabin Air Assembly to a detailed sizing model, and upgrade of the Food-management subsystem.

Translational MRI volumetry with NeuroQuant: Effects of version and normative data on relationships with memory performance in healthy older adults and patients with mild cognitive impairment

PubMed Central

Stelmokas, Julija; Yassay, Lance; Giordani, Bruno; Dodge, Hiroko H.; Dinov, Ivo D.; Bhaumik, Arijit; Sathian, K.; Hampstead, Benjamin M.

2018-01-01

NeuroQuant (NQ) is a fully-automated program that overcomes several existing limitations in the clinical translation of MRI-derived volumetry. The current study characterized differences between the original (NQ1) and an updated NQ version (NQ2) by (i) replicating previously identified relationships between neuropsychological test performance and medial temporal lobe volumes, (ii) evaluating the level of agreement between NQ versions, and (iii) determining if the addition of NQ2 age-/sex-based z-scores hold greater clinical utility for prediction of memory impairment than standard percent of intracranial volume (%ICV) values. Sixty-seven healthy older adults and 65 MCI patients underwent structural MRI and completed cognitive testing, including the Immediate and Delayed Memory indices from the RBANS. Results generally replicated previous relationships between key medial temporal lobe regions and memory test performance, though comparison of NQ regions revealed statistically different values that were biased toward one version or the other depending on the region. NQ2 hippocampal z-scores explained additional variance in memory performance relative to %ICV values. Findings indicate that NQ1/2 medial temporal lobe volumes, especially age- and sex-based z-scores, hold clinical value, though caution is warranted when directly comparing volumes across NQ versions. PMID:29060939

Useful References in Pediatric Cardiac Intensive Care: The 2017 Update.

PubMed

Uzark, Karen C; Costello, John M; DeSena, Holly C; Thiagajaran, Ravi; Smith-Parrish, Melissa; Gist, Katja M

2018-03-10

Pediatric cardiac intensive care continues to evolve, with rapid advances in knowledge and improvement in clinical outcomes. In the past, the Board of Directors of the Pediatric Cardiac Intensive Care Society created and subsequently updated a list of sentinel references focused on the care of critically ill children with congenital and acquired heart disease. The objective of this article is to provide clinicians with a compilation and brief summary of updated and useful references that have been published since 2012. Pediatric Cardiac Intensive Care Society members were solicited via a survey sent out between March 20, 2017, and April 28, 2017, to provide important references that have impacted clinical care. The survey was sent to approximately 523 members. Responses were received from 45 members, of which some included multiple references. Following review of the list of references, and removing editorials, references were compiled by the first and last author. The final list was submitted to members of the society's Research Briefs Committee, who ranked each publication. Rankings were compiled and the references with the highest scores included. Research Briefs Committee members ranked the articles from 1 to 3, with one being highly relevant and should be included and 3 being less important and should be excluded. Averages were computed, and the top articles included in this article. The first (K.C.U.) and last author (K.M.G.) reviewed and developed summaries of each article. This article contains a compilation of useful references for the critical care of children with congenital and acquired heart disease published in the last 5 years. In conjunction with the prior version of this update in 2012, this article may be used as an educational reference in pediatric cardiac intensive care.

Medicare program; prospective payment system and consolidated billing for skilled nursing facilities for FY 2014. Final rule.

PubMed

2013-08-06

This final rule updates the payment rates used under the prospective payment system for skilled nursing facilities (SNFs) for fiscal year (FY) 2014. In addition, it revises and rebases the SNF market basket, revises and updates the labor related share, and makes certain technical and conforming revisions in the regulations text. This final rule also includes a policy for reporting the SNF market basket forecast error in certain limited circumstances and adds a new item to the Minimum Data Set (MDS), Version 3.0 for reporting the number of distinct therapy days. Finally, this final rule adopts a change to the diagnosis code used to determine which residents will receive the AIDS add-on payment, effective for services provided on or after the October 1, 2014 implementation date for conversion to ICD-10-CM.

docBUILDER - Building Your Useful Metadata for Earth Science Data and Services.

NASA Astrophysics Data System (ADS)

Weir, H. M.; Pollack, J.; Olsen, L. M.; Major, G. R.

2005-12-01

The docBUILDER tool, created by NASA's Global Change Master Directory (GCMD), assists the scientific community in efficiently creating quality data and services metadata. Metadata authors are asked to complete five required fields to ensure enough information is provided for users to discover the data and related services they seek. After the metadata record is submitted to the GCMD, it is reviewed for semantic and syntactic consistency. Currently, two versions are available - a Web-based tool accessible with most browsers (docBUILDERweb) and a stand-alone desktop application (docBUILDERsolo). The Web version is available through the GCMD website, at http://gcmd.nasa.gov/User/authoring.html. This version has been updated and now offers: personalized templates to ease entering similar information for multiple data sets/services; automatic population of Data Center/Service Provider URLs based on the selected center/provider; three-color support to indicate required, recommended, and optional fields; an editable text window containing the XML record, to allow for quick editing; and improved overall performance and presentation. The docBUILDERsolo version offers the ability to create metadata records on a computer wherever you are. Except for installation and the occasional update of keywords, data/service providers are not required to have an Internet connection. This freedom will allow users with portable computers (Windows, Mac, and Linux) to create records in field campaigns, whether in Antarctica or the Australian Outback. This version also offers a spell-checker, in addition to all of the features found in the Web version.

Activities for Teaching Russian and Soviet Studies in the High School. Updated Edition.

ERIC Educational Resources Information Center

Cole, Robert A., Ed.; Vaillant, Janet G., Ed.

These teacher-developed activities help the student to gain a greater awareness of the richness of Russian history and the Soviet past. New materials have been added from the original version and much has been updated. The volume is not a full curriculum but can be integrated into existing study of the world region. The book is divided into five…

iTree-Hydro: Snow hydrology update for the urban forest hydrology model

Treesearch

Yang Yang; Theodore A. Endreny; David J. Nowak

2011-01-01

This article presents snow hydrology updates made to iTree-Hydro, previously called the Urban Forest Effects—Hydrology model. iTree-Hydro Version 1 was a warm climate model developed by the USDA Forest Service to provide a process-based planning tool with robust water quantity and quality predictions given data limitations common to most urban areas. Cold climate...

The Plant Genome Integrative Explorer Resource: PlantGenIE.org.

PubMed

Sundell, David; Mannapperuma, Chanaka; Netotea, Sergiu; Delhomme, Nicolas; Lin, Yao-Cheng; Sjödin, Andreas; Van de Peer, Yves; Jansson, Stefan; Hvidsten, Torgeir R; Street, Nathaniel R

2015-12-01

Accessing and exploring large-scale genomics data sets remains a significant challenge to researchers without specialist bioinformatics training. We present the integrated PlantGenIE.org platform for exploration of Populus, conifer and Arabidopsis genomics data, which includes expression networks and associated visualization tools. Standard features of a model organism database are provided, including genome browsers, gene list annotation, Blast homology searches and gene information pages. Community annotation updating is supported via integration of WebApollo. We have produced an RNA-sequencing (RNA-Seq) expression atlas for Populus tremula and have integrated these data within the expression tools. An updated version of the ComPlEx resource for performing comparative plant expression analyses of gene coexpression network conservation between species has also been integrated. The PlantGenIE.org platform provides intuitive access to large-scale and genome-wide genomics data from model forest tree species, facilitating both community contributions to annotation improvement and tools supporting use of the included data resources to inform biological insight. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

The Lagrangian particle dispersion model FLEXPART version 10

NASA Astrophysics Data System (ADS)

Pisso, Ignacio; Sollum, Espen; Grythe, Henrik; Kristiansen, Nina; Cassiani, Massimo; Eckhardt, Sabine; Thompson, Rona; Groot Zwaaftnik, Christine; Evangeliou, Nikolaos; Hamburger, Thomas; Sodemann, Harald; Haimberger, Leopold; Henne, Stephan; Brunner, Dominik; Burkhart, John; Fouilloux, Anne; Fang, Xuekun; Phillip, Anne; Seibert, Petra; Stohl, Andreas

2017-04-01

The Lagrangian particle dispersion model FLEXPART was in its first original release in 1998 designed for calculating the long-range and mesoscale dispersion of air pollutants from point sources, such as after an accident in a nuclear power plant. The model has now evolved into a comprehensive tool for atmospheric transport modelling and analysis. Its application fields are extended to a range of atmospheric transport processes for both atmospheric gases and aerosols, e.g. greenhouse gases, short-lived climate forces like black carbon, volcanic ash and gases as well as studies of the water cycle. We present the newest release, FLEXPART version 10. Since the last publication fully describing FLEXPART (version 6.2), the model code has been parallelised in order to allow for the possibility to speed up computation. A new, more detailed gravitational settling parametrisation for aerosols was implemented, and the wet deposition scheme for aerosols has been heavily modified and updated to provide a more accurate representation of this physical process. In addition, an optional new turbulence scheme for the convective boundary layer is available, that considers the skewness in the vertical velocity distribution. Also, temporal variation and temperature dependence of the OH-reaction are included. Finally, user input files are updated to a more convenient and user-friendly namelist format, and the option to produce the output-files in netCDF-format instead of binary format is implemented. We present these new developments and show recent model applications. Moreover, we also introduce some tools for the preparation of the meteorological input data, as well as for the processing of FLEXPART output data.

GLEAM v3: updated land evaporation and root-zone soil moisture datasets

NASA Astrophysics Data System (ADS)

Martens, Brecht; Miralles, Diego; Lievens, Hans; van der Schalie, Robin; de Jeu, Richard; Fernández-Prieto, Diego; Verhoest, Niko

2016-04-01

Evaporation determines the availability of surface water resources and the requirements for irrigation. In addition, through its impacts on the water, carbon and energy budgets, evaporation influences the occurrence of rainfall and the dynamics of air temperature. Therefore, reliable estimates of this flux at regional to global scales are of major importance for water management and meteorological forecasting of extreme events. However, the global-scale magnitude and variability of the flux, and the sensitivity of the underlying physical process to changes in environmental factors, are still poorly understood due to the limited global coverage of in situ measurements. Remote sensing techniques can help to overcome the lack of ground data. However, evaporation is not directly observable from satellite systems. As a result, recent efforts have focussed on combining the observable drivers of evaporation within process-based models. The Global Land Evaporation Amsterdam Model (GLEAM, www.gleam.eu) estimates terrestrial evaporation based on daily satellite observations of meteorological drivers of terrestrial evaporation, vegetation characteristics and soil moisture. Since the publication of the first version of the model in 2011, GLEAM has been widely applied for the study of trends in the water cycle, interactions between land and atmosphere and hydrometeorological extreme events. A third version of the GLEAM global datasets will be available from the beginning of 2016 and will be distributed using www.gleam.eu as gateway. The updated datasets include separate estimates for the different components of the evaporative flux (i.e. transpiration, bare-soil evaporation, interception loss, open-water evaporation and snow sublimation), as well as variables like the evaporative stress, potential evaporation, root-zone soil moisture and surface soil moisture. A new dataset using SMOS-based input data of surface soil moisture and vegetation optical depth will also be distributed. The most important updates in GLEAM include the revision of the soil moisture data assimilation system, the evaporative stress functions and the infiltration of rainfall. In this presentation, we will highlight the changes of the methodology and present the new datasets, their validation against in situ observations and the comparisons against alternative datasets of terrestrial evaporation, such as GLDAS-Noah, ERA-Interim and previous GLEAM datasets. Preliminary results indicate that the magnitude and the spatio-temporal variability of the evaporation estimates have been slightly improved upon previous versions of the datasets.

Management of bleeding following major trauma: an updated European guideline

PubMed Central

2010-01-01

Introduction Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes. Methods The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document presents an updated version of the guideline published by the group in 2007. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature. Results Key changes encompassed in this version of the guideline include new recommendations on coagulation support and monitoring and the appropriate use of local haemostatic measures, tourniquets, calcium and desmopressin in the bleeding trauma patient. The remaining recommendations have been reevaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies. Conclusions This guideline provides an evidence-based multidisciplinary approach to the management of critically injured bleeding trauma patients. PMID:20370902

HGVS Recommendations for the Description of Sequence Variants: 2016 Update.

PubMed

den Dunnen, Johan T; Dalgleish, Raymond; Maglott, Donna R; Hart, Reece K; Greenblatt, Marc S; McGowan-Jordan, Jean; Roux, Anne-Francoise; Smith, Timothy; Antonarakis, Stylianos E; Taschner, Peter E M

2016-06-01

The consistent and unambiguous description of sequence variants is essential to report and exchange information on the analysis of a genome. In particular, DNA diagnostics critically depends on accurate and standardized description and sharing of the variants detected. The sequence variant nomenclature system proposed in 2000 by the Human Genome Variation Society has been widely adopted and has developed into an internationally accepted standard. The recommendations are currently commissioned through a Sequence Variant Description Working Group (SVD-WG) operating under the auspices of three international organizations: the Human Genome Variation Society (HGVS), the Human Variome Project (HVP), and the Human Genome Organization (HUGO). Requests for modifications and extensions go through the SVD-WG following a standard procedure including a community consultation step. Version numbers are assigned to the nomenclature system to allow users to specify the version used in their variant descriptions. Here, we present the current recommendations, HGVS version 15.11, and briefly summarize the changes that were made since the 2000 publication. Most focus has been on removing inconsistencies and tightening definitions allowing automatic data processing. An extensive version of the recommendations is available online, at http://www.HGVS.org/varnomen. © 2016 WILEY PERIODICALS, INC.

DYNA3D Code Practices and Developments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, L.; Zywicz, E.; Raboin, P.

2000-04-21

DYNA3D is an explicit, finite element code developed to solve high rate dynamic simulations for problems of interest to the engineering mechanics community. The DYNA3D code has been under continuous development since 1976[1] by the Methods Development Group in the Mechanical Engineering Department of Lawrence Livermore National Laboratory. The pace of code development activities has substantially increased in the past five years, growing from one to between four and six code developers. This has necessitated the use of software tools such as CVS (Concurrent Versions System) to help manage multiple version updates. While on-line documentation with an Adobe PDF manualmore » helps to communicate software developments, periodically a summary document describing recent changes and improvements in DYNA3D software is needed. The first part of this report describes issues surrounding software versions and source control. The remainder of this report details the major capability improvements since the last publicly released version of DYNA3D in 1996. Not included here are the many hundreds of bug corrections and minor enhancements, nor the development in DYNA3D between the manual release in 1993[2] and the public code release in 1996.« less

Space Van system update

NASA Astrophysics Data System (ADS)

Cormier, Len

1992-07-01

The Space Van is a proposed commercial launch vehicle that is designed to carry 1150 kg to a space-station orbit for a price of $1,900,000 per flight in 1992 dollars. This price includes return on preoperational investment. Recurring costs are expected to be about $840,000 per flight. The Space Van is a fully reusable, assisted-single-stage-to orbit system. The most innovative new feature of the Space Van system is the assist-stage concept. The assist stage uses only airbreathing engines for vertical takeoff and vertical landing in the horizontal attitude and for launching the rocket-powered orbiter stage at mach 0.8 and an altitude of about 12 km. The primary version of the orbiter is designed for cargo-only without a crew. However, a passenger version of the Space Van should be able to carry a crew of two plus six passengers to a space-station orbit. Since the Space Van is nearly single-stage, performance to polar orbit drops off significantly. The cargo version should be capable of carrying 350 kg to a 400-km polar orbit. In the passenger version, the Space Van should be able to carry two crew members - or one crew member plus a passenger.

Optimization and Control of Burning Plasmas Through High Performance Computing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pankin, Alexei

This project has revived the FACETS code, that has been developed under SciDAC fund- ing in 2008-2012. The code has been dormant for a number of years after the SciDAC funding stopped. FACETS depends on external packages. The external packages and libraries such as PETSc, FFTW, HDF5 and NETCDF that are included in FACETS have evolved during these years. Some packages in FACETS are also parts of other codes such as PlasmaState, NUBEAM, GACODES, and UEDGE. These packages have been also evolved together with their host codes which include TRANSP, TGYRO and XPTOR. Finally, there is also a set ofmore » packages in FACETS that are being developed and maintained by Tech-X. These packages include BILDER, SciMake, and FcioWrappers. Many of these packages evolved significantly during the last several years and FACETS had to be updated to synchronize with the re- cent progress in the external packages. The PI has introduced new changes to the BILDER package to support the updated interfaces to the external modules. During the last year of the project, the FACETS version of the UEDGE code has been extracted from FACETS as a standalone package. The PI collaborates with the scientists from LLNL on the updated UEDGE model in FACETS. Drs. T. Rognlien, M. Umansky and A. Dimits from LLNL are contributing to this task.« less

HALE UAS Concept of Operations. Version 3.0

NASA Technical Reports Server (NTRS)

2006-01-01

This document is a system level Concept of Operations (CONOPS) from the perspective of future High Altitude Long Endurance (HALE) Unmanned Aircraft Systems (UAS) service providers and National Airspace System (NAS) users. It describes current systems (existing UAS), describes HALE UAS functions and operations to be performed (via sample missions), and offers insight into the user s environment (i.e., the UAS as a system of systems). It is intended to be a source document for NAS UAS operational requirements, and provides a construct for government agencies to use in guiding their regulatory decisions, architecture requirements, and investment strategies. Although it does not describe the technical capabilities of a specific HALE UAS system (which do, and will vary widely), it is intended to aid in requirements capture and to be used as input to the functional requirements and analysis process. The document provides a basis for development of functional requirements and operational guidelines to achieve unrestricted access into the NAS. This document is an FY06 update to the FY05 Access 5 Project-approved Concept of Operations document previously published in the Public Domain on the Access 5 open website. This version is recommended to be approved for public release also. The updates are a reorganization of materials from the previous version with the addition of an updated set of operational requirements, inclusion of sample mission scenarios, and identification of roles and responsibilities of interfaces within flight phases.

LANDFIRE 2015 Remap – Utilization of Remotely Sensed Data to Classify Existing Vegetation Type and Structure to Support Strategic Planning and Tactical Response

USGS Publications Warehouse

Picotte, Joshua J.; Long, Jordan; Peterson, Birgit; Nelson, Kurtis

2017-01-01

The LANDFIRE Program produces national scale vegetation, fuels, fire regimes, and landscape disturbance data for the entire U.S. These data products have been used to model the potential impacts of fire on the landscape [1], the wildfire risks associated with land and resource management [2, 3], and those near population centers and accompanying Wildland Urban Interface zones [4], as well as many other applications. The initial LANDFIRE National Existing Vegetation Type (EVT) and vegetation structure layers, including vegetation percent cover and height, were mapped circa 2001 and released in 2009 [5]. Each EVT is representative of the dominant plant community within a given area. The EVT layer has since been updated by identifying areas of landscape change and modifying the vegetation types utilizing a series of rules that consider the disturbance type, severity of disturbance, and time since disturbance [6, 7]. Non-disturbed areas were adjusted for vegetation growth and succession. LANDFIRE vegetation structure layers also have been updated by using data modeling techniques [see 6 for a full description]. The subsequent updated versions of LANDFIRE include LANDFIRE 2008, 2010, 2012, and LANDFIRE 2014 is being incrementally released, with all data being released in early 2017. Additionally, a comprehensive remap of the baseline data, LANDFIRE 2015 Remap, is being prototyped, and production is tentatively planned to begin in early 2017 to provide a more current baseline for future updates.

The CEOS International Directory Network: Progress and Plans, Spring, 1999

NASA Technical Reports Server (NTRS)

Olsen, Lola M.

1999-01-01

The Global Change Master Directory (GCMD) serves as the software development hub for the Committee on Earth observation Satellites' (CEOS) International Directory Network (IDN). The GCMD has upgraded the software for the IDN nodes as Version 7 of the GCMD: MD7-Oracle and MD7-Isite, as well as three other MD7 experimental interfaces. The contribution by DLR representatives (Germany) of the DLR Thesaurus will be demonstrated as an educational tool for use with MD7-Isite. The software will be installed at twelve nodes around the world: Brazil, Argentina, the Netherlands, Canada, France, Germany, Italy, Japan, Australia, New Zealand, Switzerland, and several sites in the United States. Representing NASA for the International Directory Network and the CEOS Data Access Subgroup, NASA's contribution to this international interoperability effort will be updated. Discussion will include interoperability with the CEOS Interoperability Protocol (CIP), features of the latest version of the software, including upgraded capabilities for distributed input by the IDN nodes, installation logistics, "mirroring", population objectives, and future plans.

The CEOS International Directory Network Progress and Plans: Spring, 1999

NASA Technical Reports Server (NTRS)

Olsen, Lola M.

1999-01-01

The Global Change Master Directory (GCMD) serves as the software development hub for the Committee on Earth Observation Satellites' (CEOS) International Directory Network (IDN). The GCMD has upgraded the software for the IDN nodes as Version 7 of the GCMD: MD7-Oracle and MD7-Isite, as well as three other MD7 experimental interfaces. The contribution by DLR representatives (Germany) of the DLR Thesaurus will be demonstrated as an educational tool for use with MD7-Isite. The software will be installed at twelve nodes around the world: Brazil, Argentina, the Netherlands, Canada, France, Germany, Italy, Japan, Australia, New Zealand, Switzerland, and several sites in the United States. Representing NASA for the International Directory Network and the CEOS Data Access Subgroup, NASA's contribution to this international interoperability effort will be updated. Discussion will include interoperability with the CEOS Interoperability Protocol (CIP), features of the latest version of the software, including upgraded capabilities for distributed input by the IDN nodes, installation logistics, "mirroring', population objectives, and future plans.

User Manual for Whisper-1.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Forrest B.; Rising, Michael Evan; Alwin, Jennifer Louise

2017-01-26

Whisper is a statistical analysis package developed in 2014 to support nuclear criticality safety (NCS) validation [1-3]. It uses the sensitivity profile data for an application as computed by MCNP6 [4-6] along with covariance files [7,8] for the nuclear data to determine a baseline upper-subcritical-limit (USL) for the application. Whisper version 1.0 was first developed and used at LANL in 2014 [3]. During 2015- 2016, Whisper was updated to version 1.1 and is to be included with the upcoming release of MCNP6.2. This document describes the user input and options for running whisper-1.1, including 2 perl utility scripts that simplifymore » ordinary NCS work, whisper_mcnp.pl and whisper_usl.pl. For many detailed references on the theory, applications, nuclear data & covariances, SQA, verification-validation, adjointbased methods for sensitivity-uncertainty analysis, and more – see the Whisper – NCS Validation section of the MCNP Reference Collection at mcnp.lanl.gov. There are currently over 50 Whisper reference documents available.« less

oPOSSUM: integrated tools for analysis of regulatory motif over-representation

PubMed Central

Ho Sui, Shannan J.; Fulton, Debra L.; Arenillas, David J.; Kwon, Andrew T.; Wasserman, Wyeth W.

2007-01-01

The identification of over-represented transcription factor binding sites from sets of co-expressed genes provides insights into the mechanisms of regulation for diverse biological contexts. oPOSSUM, an internet-based system for such studies of regulation, has been improved and expanded in this new release. New features include a worm-specific version for investigating binding sites conserved between Caenorhabditis elegans and C. briggsae, as well as a yeast-specific version for the analysis of co-expressed sets of Saccharomyces cerevisiae genes. The human and mouse applications feature improvements in ortholog mapping, sequence alignments and the delineation of multiple alternative promoters. oPOSSUM2, introduced for the analysis of over-represented combinations of motifs in human and mouse genes, has been integrated with the original oPOSSUM system. Analysis using user-defined background gene sets is now supported. The transcription factor binding site models have been updated to include new profiles from the JASPAR database. oPOSSUM is available at http://www.cisreg.ca/oPOSSUM/ PMID:17576675

Inertial sensors to quantify the pivot shift test in the treatment of anterior cruciate ligament injury

PubMed Central

ZAFFAGNINI, STEFANO; LOPOMO, NICOLA; SIGNORELLI, CECILIA; MUCCIOLI, GIULIO MARIA MARCHEGGIANI; BONANZINGA, TOMMASO; GRASSI, ALBERTO; RAGGI, FEDERICO; VISANI, ANDREA; MARCACCI, MAURILIO

2014-01-01

The main purpose of this article was to describe in detail, from the perspective of the clinical end user, a previously presented non-invasive methodology, applied in the treatment of anterior cruciate ligament injury, in which inertial sensors are used to quantify the pivot shift test. The outcomes obtained and relative considerations were compared with findings emerging from a review of the relevant updated literature. The detailed description here provided covers the system, the parameters identified and the testing procedure; it also includes the technical specifications of the hardware, the features introduced in the updated version of the software and the application of the system in clinical practice. The comparison of the technical considerations and clinical results with the updated literature confirmed the system’s optimal ergonomics, good reproducibility and clinical reliability. The novel approach here analyzed has been shown to overcome the weaknesses of other available devices and systems. Therefore, since it can be considered a new paradigm in the quantification of pivot shift test, we can recommend its routine use in clinical practice. PMID:25606555

Ecological Census Techniques - 2nd Edition

NASA Astrophysics Data System (ADS)

Sutherland, Edited By William J.

2006-08-01

This is an updated version of the best selling first edition, Ecological Census Techniques, with updating, some new chapters and authors. Almost all ecological and conservation work involves carrying out a census or survey. This practically focussed book describes how to plan a census, the practical details and shows with worked examples how to analyse the results. The first three chapters describe planning, sampling and the basic theory necessary for carrying out a census. In the subsequent chapters international experts describe the appropriate methods for counting plants, insects, fish, amphibians, reptiles, mammals and birds. As many censuses also relate the results to environmental variability, there is a chapter explaining the main methods. Finally, there is a list of the most common mistakes encountered when carrying out a census. Gives worked examples and describes practical details The chapter on research planning provides an approach for planning any research, not just those relating to census techniques Latest edition of a very highly-regarded book. Includes new authors, each chapter has been updated, and additional chapters on sampling and designing research programmes have been added

Management of bleeding and coagulopathy following major trauma: an updated European guideline

PubMed Central

2013-01-01

Introduction Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient. When these recommendations are implemented patient outcomes may be improved. Methods The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document represents an updated version of the guideline published by the group in 2007 and updated in 2010. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature. Results Key changes encompassed in this version of the guideline include new recommendations on the appropriate use of vasopressors and inotropic agents, and reflect an awareness of the growing number of patients in the population at large treated with antiplatelet agents and/or oral anticoagulants. The current guideline also includes recommendations and a discussion of thromboprophylactic strategies for all patients following traumatic injury. The most significant addition is a new section that discusses the need for every institution to develop, implement and adhere to an evidence-based clinical protocol to manage traumatically injured patients. The remaining recommendations have been re-evaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies. Conclusions A comprehensive, multidisciplinary approach to trauma care and mechanisms with which to ensure that established protocols are consistently implemented will ensure a uniform and high standard of care across Europe and beyond. Please see related letter by Morel et alhttp://ccforum.com/content/17/4/442 PMID:23601765

Calibrating and Updating the Global Forest Products Model (GFPM version 2014 with BPMPD)

Treesearch

Joseph Buongiorno; Shushuai Zhu

2014-01-01

The Global Forest Products Model (GFPM) is an economic model of global production, consumption, and trade of forest products. An earlier version of the model is described in Buongiorno et al. (2003). The GFPM 2014 has data and parameters to simulate changes of the forest sector from 2010 to 2030. Buongiorno and Zhu (2014) describe how to use the model for simulation....

Calibrating and updating the Global Forest Products Model (GFPM version 2016 with BPMPD)

Treesearch

Joseph Buongiorno; Shushuai  Zhu

2016-01-01

The Global Forest Products Model (GFPM) is an economic model of global production, consumption, and trade of forest products. An earlier version of the model is described in Buongiorno et al. (2003). The GFPM 2016 has data and parameters to simulate changes of the forest sector from 2013 to 2030. Buongiorno and Zhu (2015) describe how to use the model for...

Results from CrIS/ATMS Obtained Using an "AIRS Version-6 Like" Retrieval Algorithm

NASA Technical Reports Server (NTRS)

Susskind, Joel; Kouvaris, Louis; Iredell, Lena; Blaisdell, John

2015-01-01

AIRS and CrIS Version-6.22 O3(p) and q(p) products are both superior to those of AIRS Version-6.Monthly mean August 2014 Version-6.22 AIRS and CrIS products agree reasonably well with OMPS, CERES, and witheach other. JPL plans to process AIRS and CrIS for many months and compare interannual differences. Updates to thecalibration of both CrIS and ATMS are still being finalized. We are also working with JPL to develop a joint AIRS/CrISlevel-1 to level-3 processing system using a still to be finalized Version-7 retrieval algorithm. The NASA Goddard DISCwill eventually use this system to reprocess all AIRS and recalibrated CrIS/ATMS. .

Soilcrust References

Science.gov Websites

Soil Crust Home Crust 101 Advanced Gallery References CCERS Site Links Updated: April 24, 2006 References The complete biological soil crust reference list is available in three formats: HTML Version

Update of global TC simulations using a variable resolution non-hydrostatic model

NASA Astrophysics Data System (ADS)

Park, S. H.

2017-12-01

Using in a variable resolution meshes in MPAS during 2017 summer., Tropical cyclone (TC) forecasts are simulated. Two physics suite are tested to explore performance and bias of each physics suite for TC forecasting. A WRF physics suite is selected from experience on weather forecasting and CAM (Community Atmosphere Model) physics is taken from a AMIP type climate simulation. Based on the last year results from CAM5 physical parameterization package and comparing with WRF physics, we investigated a issue with intensity bias using updated version of CAM physics (CAM6). We also compared these results with coupled version of TC simulations. During this talk, TC structure will be compared specially around of boundary layer and investigate their relationship between TC intensity and different physics package.

MODFLOW-OWHM v2: New Features and Improvements; The Next Generation of MODFLOW Conjunctive Use Simulation

NASA Astrophysics Data System (ADS)

Boyce, S. E.; Hanson, R. T.; Henson, W.; Ferguson, I. M.; Schmid, W.; Reimann, T.; Mehl, S.

2017-12-01

The One-Water Hydrologic Flow Model (One-Water) is a MODFLOW-based integrated hydrologic flow model designed for the analysis of a broad range of conjunctive-use and sustainability issues. It was motivated by the need to merge the multiple variants of MODFLOW-2005 to yield an enhanced unified version capable of simulating conjunctive use and management, sustainability, climate-related issues, and managing the relationships between groundwater, surface water, and land usage. One-Water links the movement and use of groundwater, surface water, and imported water for consumption by agriculture and natural vegetation on the landscape, and for potable and other uses within a supply-and-demand framework. The first version, released in 2014, was selected by The World Bank Water Resource Software Review in 2016 as one of three recommended simulation programs for conjunctive use and management modeling. One-Water is also being used as the primary simulation engine for FREEWAT, a European Union sponsored open-source water management software environment. The next version of One-Water will include a new surface-water operations module that simulates dynamic reservoir operations and a conduit-flow process for karst aquifers and leaky pipe networks. It will also include enhancements to local grid refinement, and additional features to facilitate easier model updates, faster execution, better error messages, and more integration/cross communication between the traditional MODFLOW packages. The new structure also helps facilitate the new integration into a "Self-Updating" structure of data streams, simulation, and analysis needed for modern water resource management. By retaining and tracking the water within the hydrosphere, One-Water accounts for "all of the water everywhere and all of the time." This philosophy provides more confidence in the water accounting to the scientific community and provides the public a foundation needed to address wider classes of problems. Ultimately, more complex questions are being asked about water resources, requiring tools that more completely answer conjunctive-use management questions.

Photoionization and High Density Gas

NASA Technical Reports Server (NTRS)

Kallman, T.; Bautista, M.; White, Nicholas E. (Technical Monitor)

2002-01-01

We present results of calculations using the XSTAR version 2 computer code. This code is loosely based on the XSTAR v.1 code which has been available for public use for some time. However it represents an improvement and update in several major respects, including atomic data, code structure, user interface, and improved physical description of ionization/excitation. In particular, it now is applicable to high density situations in which significant excited atomic level populations are likely to occur. We describe the computational techniques and assumptions, and present sample runs with particular emphasis on high density situations.

Reliability analysis of laminated CMC components through shell subelement techniques

NASA Technical Reports Server (NTRS)

Starlinger, A.; Duffy, S. F.; Gyekenyesi, J. P.

1992-01-01

An updated version of the integrated design program C/CARES (composite ceramic analysis and reliability evaluation of structures) was developed for the reliability evaluation of CMC laminated shell components. The algorithm is now split in two modules: a finite-element data interface program and a reliability evaluation algorithm. More flexibility is achieved, allowing for easy implementation with various finite-element programs. The new interface program from the finite-element code MARC also includes the option of using hybrid laminates and allows for variations in temperature fields throughout the component.

The EFSUMB website, a great source for ultrasound information and education.

PubMed

Dietrich, Christoph F; Rudd, Lynne; Saftiou, Adrian; Gilja, Odd Helge

2017-01-31

The aim of this updated EFSUMB-website guide is to introduce readers to EFSUMB's wide ranging activities. The most recent are the guidelines on interventional ultrasound and intestinal ultrasound and updated CEUS Non-Liver and Elastography Liver Guidelines which can be freely downloaded. Hosting eBooks on our website is another new departure, most importantly the EFSUMB Course Book on Ultrasound available in a second edition as an eReader and an online Student Edition of the ECB. EFSUMB has been active with updating Guidelines; those mentioned above have all been revised or written in thelast two years. Webinars have been introduced and participation is possible online but can be reviewed later along with recent recordings of Euroson Schools. The EFSUMB Newsletter in the EJU promotes our activities and topical articles intended to reach all our members with the online version hosted on our website. The Case of the Month continues to be one of EFSUMB's most visited sites and in the last few years has been translated into 14 different languages including Chinese. In conclusion, this article aims to provide an updated guide to the website educational sites of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB).

COS Target Acquisition Guidelines, Recommendations, and Interpretation

NASA Astrophysics Data System (ADS)

Keyes, Charles (Tony) D.; Penton, Steven V.

2010-06-01

Based upon analysis of SMOV and Cycle 17 observations through April 2010, this ISR expands, updates, and supersedes recommendations and information provided about target acquisitions (TA) in the COS Instrument Handbook version 2. This ISR provides an overview of COS TA, presents general guidelines and recommendations for crafting COS TAs, establishes COS TA centering accuracy requirements to achieve COS photometric, velocity, and resolution objectives, and summarizes the performance of the COS on-board TA modes as compared to these centering requirements. Updated TA strategy recommendations are given where appropriate, a user-oriented table lists where to find important quantities for the analysis and interpretation of COS TAs, and a brief appendix with additional supporting information is included. An overview of COS TA strategies is provided in Section 2 and Table 1; important updates to ACQ/SEARCH requirements and SEARCH-SIZE recommendations as a function of target coordinate accuracy are given in Tables 2 and 3; COS TA performance by mode is described in Section 5; important header keywords that are useful for evaluating the quality of COS TAs are listed in Table 5 along with where to find them; Table 6 gives a summary of COS TA modes, options, and recommended values; Section 7 summarizes updated recommendations and guidelines for COS TA; and Appendix A provides additional useful COS TA information.

Simulated and observed 2010 floodwater elevations in selected river reaches in the Pawtuxet River Basin, Rhode Island

USGS Publications Warehouse

Zarriello, Phillip J.; Olson, Scott A.; Flynn, Robert H.; Strauch, Kellan R.; Murphy, Elizabeth A.

2014-01-01

Heavy, persistent rains from late February through March 2010 caused severe flooding that set, or nearly set, peaks of record for streamflows and water levels at many long-term streamgages in Rhode Island. In response to this event, hydraulic models were updated for selected reaches covering about 56 river miles in the Pawtuxet River Basin to simulate water-surface elevations (WSEs) at specified flows and boundary conditions. Reaches modeled included the main stem of the Pawtuxet River, the North and South Branches of the Pawtuxet River, Pocasset River, Simmons Brook, Dry Brook, Meshanticut Brook, Furnace Hill Brook, Flat River, Quidneck Brook, and two unnamed tributaries referred to as South Branch Pawtuxet River Tributary A1 and Tributary A2. All the hydraulic models were updated to Hydrologic Engineering Center-River Analysis System (HEC-RAS) version 4.1.0 using steady-state simulations. Updates to the models included incorporation of new field-survey data at structures, high resolution land-surface elevation data, and updated flood flows from a related study. The models were assessed using high-water marks (HWMs) obtained in a related study following the March– April 2010 flood and the simulated water levels at the 0.2-percent annual exceedance probability (AEP), which is the estimated AEP of the 2010 flood in the basin. HWMs were obtained at 110 sites along the main stem of the Pawtuxet River, the North and South Branches of the Pawtuxet River, Pocasset River, Simmons Brook, Furnace Hill Brook, Flat River, and Quidneck Brook. Differences between the 2010 HWM elevations and the simulated 0.2-percent AEP WSEs from flood insurance studies (FISs) and the updated models developed in this study varied with most differences attributed to the magnitude of the 0.2-percent AEP flows. WSEs from the updated models generally are in closer agreement with the observed 2010 HWMs than with the FIS WSEs. The improved agreement of the updated simulated water elevations to observed 2010 HWMs provides a measure of the hydraulic model performance, which indicates the updated models better represent flooding at other AEPs than the existing FIS models.

Does updating improve the methodological and reporting quality of systematic reviews?

PubMed

Shea, Beverley; Boers, Maarten; Grimshaw, Jeremy M; Hamel, Candyce; Bouter, Lex M

2006-06-13

Systematic reviews (SRs) must be of high quality. The purpose of our research was to compare the methodological and reporting quality of original versus updated Cochrane SRs to determine whether updating had improved these two quality dimensions. We identified updated Cochrane SRs published in issue 4, 2002 of the Cochrane Library. We assessed the updated and original versions of the SRs using two instruments: the 10 item enhanced Overview Quality Assessment Questionnaire (OQAQ), and an 18-item reporting quality checklist and flow chart based upon the Quality of Reporting of Meta-analyses (QUOROM) statement. At least two reviewers extracted data and assessed quality. We calculated the percentage (with a 95% confidence interval) of 'yes' answers to each question. We calculated mean differences in percentage, 95% confidence intervals and p-values for each of the individual items and the overall methodological quality score of the updated and pre-updated versions using OQAQ. We assessed 53 SRs. There was no significant improvement in the global quality score of the OQAQ (mean difference 0.11 (-0.28; 0.70 p = 0.52)). Updated reviews showed a significant improvement of 18.9 (7.2; 30.6 p < .01) on the OQAQ item assessing whether the conclusions drawn by the author(s) were supported by the data and/or analysis presented in the SR. The QUOROM statement showed that the quality of reporting of Cochrane reviews improved in some areas with updating. Improvements were seen on the items relating to data sources reported in the abstract, with a significant difference of 17.0 (9.8; 28.7 p = 0.01), review methods, reported in the abstract 35 (24.1; 49.1 p = 0.00), searching methods 18.9 (9.7; 31.6 p = 0.01), and data abstraction 18.9 (11.7; 30.9 p = 0.00). The overall quality of Cochrane SRs is fair-to-good. Although reporting quality improved on certain individual items there was no overall improvement seen with updating and methodological quality remained unchanged. Further improvement of quality of reporting is possible. There is room for improvement of methodological quality as well. Authors updating reviews should address identified methodological or reporting weaknesses. We recommend to give full attention to both quality domains when updating SRs.

Status of the NASA GMAO Observing System Simulation Experiment

NASA Technical Reports Server (NTRS)

Prive, Nikki C.; Errico, Ronald M.

2014-01-01

An Observing System Simulation Experiment (OSSE) is a pure modeling study used when actual observations are too expensive or difficult to obtain. OSSEs are valuable tools for determining the potential impact of new observing systems on numerical weather forecasts and for evaluation of data assimilation systems (DAS). An OSSE has been developed at the NASA Global Modeling and Assimilation Office (GMAO, Errico et al 2013). The GMAO OSSE uses a 13-month integration of the European Centre for Medium- Range Weather Forecasts 2005 operational model at T511/L91 resolution for the Nature Run (NR). Synthetic observations have been updated so that they are based on real observations during the summer of 2013. The emulated observation types include AMSU-A, MHS, IASI, AIRS, and HIRS4 radiance data, GPS-RO, and conventional types including aircraft, rawinsonde, profiler, surface, and satellite winds. The synthetic satellite wind observations are colocated with the NR cloud fields, and the rawinsondes are advected during ascent using the NR wind fields. Data counts for the synthetic observations are matched as closely as possible to real data counts, as shown in Figure 2. Errors are added to the synthetic observations to emulate representativeness and instrument errors. The synthetic errors are calibrated so that the statistics of observation innovation and analysis increments in the OSSE are similar to the same statistics for assimilation of real observations, in an iterative method described by Errico et al (2013). The standard deviations of observation minus forecast (xo-H(xb)) are compared for the OSSE and real data in Figure 3. The synthetic errors include both random, uncorrelated errors, and an additional correlated error component for some observational types. Vertically correlated errors are included for conventional sounding data and GPS-RO, and channel correlated errors are introduced to AIRS and IASI (Figure 4). HIRS, AMSU-A, and MHS have a component of horizontally correlated error. The forecast model used by the GMAO OSSE is the Goddard Earth Observing System Model, Version 5 (GEOS-5) with Gridpoint Statistical Interpolation (GSI) DAS. The model version has been updated to v. 5.13.3, corresponding to the current operational model. Forecasts are run on a cube-sphere grid with 180 points along each edge of the cube (approximately 0.5 degree horizontal resolution) with 72 vertical levels. The DAS is cycled at 6-hour intervals, with 240 hour forecasts launched daily at 0000 UTC. Evaluation of the forecasting skill for July and August is currently underway. Prior versions of the GMAO OSSE have been found to have greater forecasting skill than real world forecasts. It is anticipated that similar forecast skill will be found in the updated OSSE.

How updating textual clinical practice guidelines impacts clinical decision support systems: a case study with bladder cancer management.

PubMed

Bouaud, Jacques; Séroussi, Brigitte; Brizon, Ambre; Culty, Thibault; Mentré, France; Ravery, Vincent

2007-01-01

Guideline-based clinical decision support systems (CDSSs) can be effective in increasing physician compliance with recommendations. However, the ever growing pace at which medical knowledge is produced requires that clinical practice guidelines (CPGs) be updated regularly. It is therefore mandatory that CDSSs be revised accordingly. The French Association for Urology publishes CPGs on bladder cancer management every 2 years. We studied the impact of the 2004 revision of these guidelines, with respect to the 2002 version with a CDSS, UroDoc. We proposed a typology of knowledge base modifications resulting from the update of CPGs making the difference between practice, clinical conditions and recommendations refinement as opposed to new practice and new recommendations. The number of formalized recommendations increased from 577 in 2002 to 1,081 in 2004. We evaluated the two versions of UroDoc on a randomized sample of patient records. A single new practice that modifies a decision taken in 49% of all recorded decisions leads to a fall from 67% to 46% of the compliance rate of decisions.

Risk Assessment Update: Russian Segment

NASA Technical Reports Server (NTRS)

Christiansen, Eric; Lear, Dana; Hyde, James; Bjorkman, Michael; Hoffman, Kevin

2012-01-01

BUMPER-II version 1.95j source code was provided to RSC-E- and Khrunichev at January 2012 MMOD TIM in Moscow. MEMCxP and ORDEM 3.0 environments implemented as external data files. NASA provided a sample ORDEM 3.0 g."key" & "daf" environment file set for demonstration and benchmarking BUMPER -II v1.95j installation at the Jan-12 TIM. ORDEM 3.0 has been completed and is currently in beta testing. NASA will provide a preliminary set of ORDEM 3.0 ".key" & ".daf" environment files for the years 2012 through 2028. Bumper output files produced using the new ORDEM 3.0 data files are intended for internal use only, not for requirements verification. Output files will contain these words ORDEM FILE DESCRIPTION = PRELIMINARY VERSION: not for production. The projectile density term in many BUMPER-II ballistic limit equations will need to be updated. Cube demo scripts and output files delivered at the Jan-12 TIM have been updated for the new ORDEM 3.0 data files. Risk assessment results based on ORDEM 3.0 and MEM will be presented for the Russian Segment (RS) of ISS.

Compendium of Experimental Cetane Numbers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yanowitz, Janet; Ratcliff, Matthew A.; McCormick, Robert L.

This report is an updated version of the 2014 Compendium of Experimental Cetane Number Data and presents a compilation of measured cetane numbers for pure chemical compounds. It includes all available single-compound cetane number data found in the scientific literature up until December 2016 as well as a number of previously unpublished values, most measured over the past decade at the National Renewable Energy Laboratory. This version of the compendium contains cetane values for 496 pure compounds, including 204 hydrocarbons and 292 oxygenates. 176 individual measurements are new to this version of the compendium, all of them collected using ASTMmore » Method D6890, which utilizes an Ignition Quality Tester (IQT) a type of constant-volume combustion chamber. For many compounds, numerous measurements are included, often collected by different researchers using different methods. The text of this document is unchanged from the 2014 version, except for the numbers of compounds in Section 3.1, the Appendices, Table 1. Primary Cetane Number Data Sources and Table 2. Number of Measurements Included in Compendium. Cetane number is a relative ranking of a fuel's autoignition characteristics for use in compression ignition engines. It is based on the amount of time between fuel injection and ignition, also known as ignition delay. The cetane number is typically measured either in a single-cylinder engine or a constant-volume combustion chamber. Values in the previous compendium derived from octane numbers have been removed and replaced with a brief analysis of the correlation between cetane numbers and octane numbers. The discussion on the accuracy and precision of the most commonly used methods for measuring cetane number has been expanded, and the data have been annotated extensively to provide additional information that will help the reader judge the relative reliability of individual results.« less

EnergyPlus™

DOE Office of Scientific and Technical Information (OSTI.GOV)

Originally developed in 1999, an updated version 8.8.0 with bug fixes was released on September 30th, 2017. EnergyPlus™ is a whole building energy simulation program that engineers, architects, and researchers use to model both energy consumption—for heating, cooling, ventilation, lighting and plug and process loads—and water use in buildings. EnergyPlus is a console-based program that reads input and writes output to text files. It ships with a number of utilities including IDF-Editor for creating input files using a simple spreadsheet-like interface, EP-Launch for managing input and output files and performing batch simulations, and EP-Compare for graphically comparing the results ofmore » two or more simulations. Several comprehensive graphical interfaces for EnergyPlus are also available. DOE does most of its work with EnergyPlus using the OpenStudio® software development kit and suite of applications. DOE releases major updates to EnergyPlus twice annually.« less

HEPLIB `91: International users meeting on the support and environments of high energy physics computing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnstad, H.

The purpose of this meeting is to discuss the current and future HEP computing support and environments from the perspective of new horizons in accelerator, physics, and computing technologies. Topics of interest to the Meeting include (but are limited to): the forming of the HEPLIB world user group for High Energy Physic computing; mandate, desirables, coordination, organization, funding; user experience, international collaboration; the roles of national labs, universities, and industry; range of software, Monte Carlo, mathematics, physics, interactive analysis, text processors, editors, graphics, data base systems, code management tools; program libraries, frequency of updates, distribution; distributed and interactive computing, datamore » base systems, user interface, UNIX operating systems, networking, compilers, Xlib, X-Graphics; documentation, updates, availability, distribution; code management in large collaborations, keeping track of program versions; and quality assurance, testing, conventions, standards.« less

HEPLIB 91: International users meeting on the support and environments of high energy physics computing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnstad, H.

The purpose of this meeting is to discuss the current and future HEP computing support and environments from the perspective of new horizons in accelerator, physics, and computing technologies. Topics of interest to the Meeting include (but are limited to): the forming of the HEPLIB world user group for High Energy Physic computing; mandate, desirables, coordination, organization, funding; user experience, international collaboration; the roles of national labs, universities, and industry; range of software, Monte Carlo, mathematics, physics, interactive analysis, text processors, editors, graphics, data base systems, code management tools; program libraries, frequency of updates, distribution; distributed and interactive computing, datamore » base systems, user interface, UNIX operating systems, networking, compilers, Xlib, X-Graphics; documentation, updates, availability, distribution; code management in large collaborations, keeping track of program versions; and quality assurance, testing, conventions, standards.« less

Update Direct-Strike Lightning Environment for Stockpile-to-Target Sequence (Second Revision)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uman, Martin A.; Rakov, V. A.; Elisme, J. O.

2010-10-05

The University of Florida has surveyed all relevant publications reporting lightning characteristics and presents here an up-to-date version of the direct-strike lightning environment specifications for nuclear weapons published in 1989 by R. J. Fisher and M. A. Uman. Further, we present functional expressions for current vs. time, current derivative vs. time, second current derivative vs. time, charge transfer vs. time, and action integral (specific energy) vs. time for positive and negative first return strokes, for negative subsequent return strokes, and for positive and negative continuing currents; and we give sets of constants for these functional expressions so that the resultantmore » waveforms exhibit approximately the median and extreme lightning parameters presented in the updated direct strike environment. Fourier transforms of the return stroke current waveforms are presented. The results of our literature survey are included in three Appendices entitled Return Stroke Current, Continuing Current, and Positive Lightning.« less

DOT2: Macromolecular Docking With Improved Biophysical Models

PubMed Central

Roberts, Victoria A.; Thompson, Elaine E.; Pique, Michael E.; Perez, Martin S.; Eyck, Lynn Ten

2015-01-01

Computational docking is a useful tool for predicting macromolecular complexes, which are often difficult to determine experimentally. Here we present the DOT2 software suite, an updated version of the DOT intermolecular docking program. DOT2 provides straightforward, automated construction of improved biophysical models based on molecular coordinates, offering checkpoints that guide the user to include critical features. DOT has been updated to run more quickly, allow flexibility in grid size and spacing, and generate a complete list of favorable candidate configu-rations. Output can be filtered by experimental data and rescored by the sum of electrostatic and atomic desolvation energies. We show that this rescoring method improves the ranking of correct complexes for a wide range of macromolecular interactions, and demonstrate that biologically relevant models are essential for biologically relevant results. The flexibility and versatility of DOT2 accommodate realistic models of complex biological systems, improving the likelihood of a successful docking outcome. PMID:23695987

Resource Tracking Model Updates and Trade Studies

NASA Technical Reports Server (NTRS)

Chambliss, Joe; Stambaugh, Imelda; Moore, Michael

2016-01-01

The Resource tracking model has been updated to capture system manager and project manager inputs. Both the Trick/GUNNS RTM simulator and the RTM mass balance spreadsheet have been revised to address inputs from system managers and to refine the way mass balance is illustrated. The revisions to the RTM included addition of a Plasma Pyrolysis Assembly (PPA) to recover hydrogen from Sabatier reactor methane which was vented in the prior version of the RTM. The effect of the PPA on the overall balance of resources in an exploration vehicle is illustrated in the increased recycle of vehicle oxygen. Additionally simulation of EVAs conducted from the exploration module was added. Since the focus of the exploration module is to provide a habitat during deep space operations the EVA simulation approach to EVA is based on ISS EVA protocol and processes. Case studies have been run to show the relative effect of performance changes on vehicle resources.

Satellite Power Systems (SPS) concept definition study (Exhibit D). Volume 7: System/subsystems requirements databook

NASA Technical Reports Server (NTRS)

Hanley, G. M.

1981-01-01

This volume summarizes the basic requirements used as a guide to systems analysis, and is a basis for the selection of candidate Satellite Power Systems (SPS) point designs. Initially, these collected data reflected the level of definition resulting from the evaluation of a broad spectrum of SPS concepts. As the various concepts matured, these requirements were updated to reflect the requirements identified for the projected satellite system/subsystem point designs. Included is an updated version of earlier Rockwell concepts using klystrons as the specific microwave power amplification approach, as well as a more in-depth definition, analysis and preliminary point design on two concepts based on the use of advanced solid state technology to accomplish the task of high power amplification of the 2.45 GHz transmitted power beam to the Earth receiver. Finally, a preliminary definition of a concept using magnetrons as the microwave power amplifiers is presented.

The NTCIP guide : updated version 3

DOT National Transportation Integrated Search

2002-10-01

The transportation community has long needed transportation systems that could be built using devices and components that were interchangeable and interoperable. The National Transportation Communications for ITS Protocol (NTCIP) family of standards ...

Evaluation of the Community Multi-scale Air Quality (CMAQ) ...

EPA Pesticide Factsheets

The Community Multiscale Air Quality (CMAQ) model is a state-of-the-science air quality model that simulates the emission, transport and fate of numerous air pollutants, including ozone and particulate matter. The Computational Exposure Division (CED) of the U.S. Environmental Protection Agency develops the CMAQ model and periodically releases new versions of the model that include bug fixes and various other improvements to the modeling system. In the fall of 2015, CMAQ version 5.1 was released. This new version of CMAQ will contain important bug fixes to several issues that were identified in CMAQv5.0.2 and additionally include updates to other portions of the code. Several annual, and numerous episodic, CMAQv5.1 simulations were performed to assess the impact of these improvements on the model results. These results will be presented, along with a base evaluation of the performance of the CMAQv5.1 modeling system against available surface and upper-air measurements available during the time period simulated. The National Exposure Research Laboratory (NERL) Computational Exposure Division (CED) develops and evaluates data, decision-support tools, and models to be applied to media-specific or receptor-specific problem areas. CED uses modeling-based approaches to characterize exposures, evaluate fate and transport, and support environmental diagnostics/forensics with input from multiple data sources. It also develops media- and receptor-specific models, proces

Earthquake Hazard and Risk in New Zealand

NASA Astrophysics Data System (ADS)

Apel, E. V.; Nyst, M.; Fitzenz, D. D.; Molas, G.

2014-12-01

To quantify risk in New Zealand we examine the impact of updating the seismic hazard model. The previous RMS New Zealand hazard model is based on the 2002 probabilistic seismic hazard maps for New Zealand (Stirling et al., 2002). The 2015 RMS model, based on Stirling et al., (2012) will update several key source parameters. These updates include: implementation a new set of crustal faults including multi-segment ruptures, updating the subduction zone geometry and reccurrence rate and implementing new background rates and a robust methodology for modeling background earthquake sources. The number of crustal faults has increased by over 200 from the 2002 model, to the 2012 model which now includes over 500 individual fault sources. This includes the additions of many offshore faults in northern, east-central, and southwest regions. We also use the recent data to update the source geometry of the Hikurangi subduction zone (Wallace, 2009; Williams et al., 2013). We compare hazard changes in our updated model with those from the previous version. Changes between the two maps are discussed as well as the drivers for these changes. We examine the impact the hazard model changes have on New Zealand earthquake risk. Considered risk metrics include average annual loss, an annualized expected loss level used by insurers to determine the costs of earthquake insurance (and premium levels), and the loss exceedance probability curve used by insurers to address their solvency and manage their portfolio risk. We analyze risk profile changes in areas with large population density and for structures of economic and financial importance. New Zealand is interesting in that the city with the majority of the risk exposure in the country (Auckland) lies in the region of lowest hazard, where we don't have a lot of information about the location of faults and distributed seismicity is modeled by averaged Mw-frequency relationships on area sources. Thus small changes to the background rates can have a large impact on the risk profile for the area. Wellington, another area of high exposure is particularly sensitive to how the Hikurangi subduction zone and the Wellington fault are modeled. Minor changes on these sources have substantial impacts for the risk profile of the city and the country at large.

Documentation for the machine-readable version of the Smithsonian Astrophysical Observatory Star catalogue (SAO) version 1984

NASA Technical Reports Server (NTRS)

Roman, N. G.; Warren, W. H., Jr.

1984-01-01

An updated, corrected and extended machine readable version of the Smithsonian Astrophysical Observatory star catalog (SAO) is described. Published and unpublished errors discovered in the previous version have been corrected, and multiple star and supplemental BD identifications added to stars where more than one SAO entry has the same Durchmusterung number. Henry Draper Extension (HDE) numbers have been added for stars found in both volumes of the extension. Data for duplicate SAO entries (those referring to the same star) have been blanked out, but the records themselves have been retained and flagged so that sequencing and record count are identical to the published catalog.

Publisher Correction: Western US volcanism due to intruding oceanic mantle driven by ancient Farallon slabs

NASA Astrophysics Data System (ADS)

Zhou, Quan; Liu, Lijun; Hu, Jiashun

2018-05-01

In the version of this Article originally published, data points representing mafic eruptions were missing from Fig. 4b, the corrected version is shown below. Furthermore, the authors omitted to include the following acknowledgements to the provider of the computational resources: "This research is part of the Blue Waters sustained-petascale computing project, which is supported by the National Science Foundation (awards OCI-0725070 and ACI-1238993) and the state of Illinois. Blue Waters is a joint effort of the University of Illinois at Urbana-Champaign and its National Center for Supercomputing Applications. This work is also part of the `PRAC Title 4-D Geodynamic Modeling With Data Assimilation: Origin Of Intra-Plate Volcanism In The Pacific Northwest' PRAC allocation support by the National Science Foundation (award number ACI 1516586). This work also used the Extreme Science and Engineering Discovery Environment (XSEDE), which is supported by National Science Foundation grant number ACI-1548562." Figure 4 and the Acknowledgements section have been updated in the online version of the Article.

Mi-DISCOVERER: A bioinformatics tool for the detection of mi-RNA in human genome.

PubMed

Arshad, Saadia; Mumtaz, Asia; Ahmad, Freed; Liaquat, Sadia; Nadeem, Shahid; Mehboob, Shahid; Afzal, Muhammad

2010-11-27

MicroRNAs (miRNAs) are 22 nucleotides non-coding RNAs that play pivotal regulatory roles in diverse organisms including the humans and are difficult to be identified due to lack of either sequence features or robust algorithms to efficiently identify. Therefore, we made a tool that is Mi-Discoverer for the detection of miRNAs in human genome. The tools used for the development of software are Microsoft Office Access 2003, the JDK version 1.6.0, BioJava version 1.0, and the NetBeans IDE version 6.0. All already made miRNAs softwares were web based; so the advantage of our project was to make a desktop facility to the user for sequence alignment search with already identified miRNAs of human genome present in the database. The user can also insert and update the newly discovered human miRNA in the database. Mi-Discoverer, a bioinformatics tool successfully identifies human miRNAs based on multiple sequence alignment searches. It's a non redundant database containing a large collection of publicly available human miRNAs.

Mi-DISCOVERER: A bioinformatics tool for the detection of mi-RNA in human genome

PubMed Central

Arshad, Saadia; Mumtaz, Asia; Ahmad, Freed; Liaquat, Sadia; Nadeem, Shahid; Mehboob, Shahid; Afzal, Muhammad

2010-01-01

MicroRNAs (miRNAs) are 22 nucleotides non-coding RNAs that play pivotal regulatory roles in diverse organisms including the humans and are difficult to be identified due to lack of either sequence features or robust algorithms to efficiently identify. Therefore, we made a tool that is Mi-Discoverer for the detection of miRNAs in human genome. The tools used for the development of software are Microsoft Office Access 2003, the JDK version 1.6.0, BioJava version 1.0, and the NetBeans IDE version 6.0. All already made miRNAs softwares were web based; so the advantage of our project was to make a desktop facility to the user for sequence alignment search with already identified miRNAs of human genome present in the database. The user can also insert and update the newly discovered human miRNA in the database. Mi-Discoverer, a bioinformatics tool successfully identifies human miRNAs based on multiple sequence alignment searches. It's a non redundant database containing a large collection of publicly available human miRNAs. PMID:21364831

An updated rate-of-spread clock

USGS Publications Warehouse

Kolaks, Jeremy; Grabner, Keith W.; Hartman, George; Cutter, Bruce E.; Loewenstein, Edward F.

2005-01-01

Several years ago, Blank and Simard (1983) described an electronic timer, frequently referred to as a rate-of-spread (ROS) clock—a relatively simple instrument used in measuring fire spread. Although other techniques for measuring rate of spread are available (such as data loggers), the basic ROS clock remains a valuable and relatively inexpensive tool. However, several items described in the original article have changed. Therefore, we are describing an updated version of the ROS clock.

A Performance Evaluation of Online Warehouse Update Algorithms

DTIC Science & Technology

1998-01-01

present one possible implementation of this coordination through a relational table, veta (short for VErsion TAble), but it should be fairly...straightforward to implement it in main memory instead5 . In order to store both Tsafe and the Tquery variables of all active readers, table veta has two...Tsafe, otherwise vn = Tquery of one reader. After describing the schema for veta , we will present in detail the steps the Updater, Reader, Garbage

Editorial: The publication of geoscientific model developments v1.1

NASA Astrophysics Data System (ADS)

Executive Editors, GMD

2015-10-01

Version 1.0 of the editorial of the EGU (European Geosciences Union) journal, Geoscientific Model Development (GMD), was published in 2013. In that editorial an assessment was made of the progress the journal had made since it started, and some revisions to the editorial policy were introduced. After 2 years of experience with this revised editorial policy there are a few required updates, refinements and clarifications, so here we present version 1.1 of the editorial. The most significant amendments relate to the peer-review criteria as presented in the Framework for GMD manuscript types, which is published as an appendix to this paper and also available on the GMD manuscript types webpage. We also slightly refine and update the Publication guide and introduce a self-contained code and data policy. The changes are summarised as follows: - All manuscript types are now required to include code or data availability paragraphs, and model code must always be made available (in the case of copyright or other legal issues, to the editor at a minimum). - The role of evaluation in GMD papers is clarified, and a separate evaluation paper type is introduced. Model descriptions must already be published or in peer review when separate evaluation papers are submitted. - Observationally derived data should normally be published in a data journal rather than in GMD. Syntheses of data which were specifically designed for tasks such as model boundary conditions or direct evaluation of model output may, however, be published in GMD. - GMD publishes a broad range of different kinds of models, and this fact is now more explicitly acknowledged. - The main changes to the Publication guide are the addition of guidelines for editors when assessing papers at the initial review stage. Before sending papers for peer review, editors are required to make sure that papers comply with the Framework for GMD paper types and to carefully consider the topic of plagiarism. - A new appendix, the GMD code and data policy, is included. Version 1.1 of the manuscript types and Publication guide are included in the appendices with changed sentences marked in bold font.

Gerson Therapy (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about Gerson therapy as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

Gonzalez Regimen (PDQ®)—Patient Version

Cancer.gov

Expert-reviewed information summary about the Gonzalez regimen as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

2002 Construction manual

DOT National Transportation Integrated Search

2002-01-01

The Illinois Department of Transportation's Highway Construction Manual has been updated from its previous version. All previous editions of this manual are now obsolete and changes in content have been marked. The Construction Manual provides inform...

Improving the representation of secondary organic aerosol (SOA) in the MOZART-4 global chemical transport model

NASA Astrophysics Data System (ADS)

Mahmud, A.; Barsanti, K. C.

2012-12-01

The secondary organic aerosol (SOA) module in the Model for Ozone and Related chemical Tracers, version 4 (MOZART-4) has been updated by replacing existing two-product (2p) parameters with those obtained from two-product volatility basis set (2p-VBS) fits, and by treating SOA formation from the following volatile organic compounds (VOCs): isoprene, propene and lumped alkenes. Strong seasonal and spatial variations in global SOA distributions were demonstrated, with significant differences in the predicted concentrations between the base-case and updated model versions. The base-case MOZART-4 predicted annual average SOA of 0.36 ± 0.50 μg m-3 in South America, 0.31 ± 0.38 μg m-3 in Indonesia, 0.09 ± 0.05 μg m-3 in the USA, and 0.12 ± 0.07 μg m-3 in Europe. Concentrations from the updated versions of the model showed a~marked increase in annual average SOA. Using the updated set of parameters alone (MZ4-v1) increased annual average SOA by ~8%, ~16%, ~56%, and ~108% from the base-case in South America, Indonesia, USA, and Europe, respectively. Treatment of additional parent VOCs (MZ4-v2) resulted in an even more dramatic increase of ~178-406% in annual average SOA for these regions over the base-case. The increases in predicted SOA concentrations further resulted in increases in corresponding SOA contributions to annual average total aerosol optical depth (AOD) by <1% for MZ4-v1 and ~1-6% for MZ4-v2. Estimated global SOA production was ~6.6 Tg yr-1 and ~19.1 Tg yr-1 with corresponding burdens of ~0.24 Tg and ~0.59 Tg using MZ4-v1 and MZ4-v2, respectively. The SOA budgets predicted in the current study fall well within reported ranges for similar modeling studies, 6.7 to 96 Tg yr-1, but are lower than recently reported observationally-constrained values, 50 to 380 Tg yr-1. With MZ4-v2, simulated SOA concentrations at the surface were also in reasonable agreement with comparable modeling studies and observations. Concentrations of estimated organic aerosol (OA) at the surface, however, showed under-prediction in Europe and over-prediction in the Amazonian regions and Malaysian Borneo during certain months of the year. Overall, the updated version of MOZART-4, MZ4-v2, showed consistently better skill in predicting SOA and OA levels and spatial distributions as compared with unmodified MOZART-4. The MZ4-v2 updates may be particularly important when MOZART-4 output is used to generate boundary conditions for regional air quality simulations that require more accurate representation of SOA concentrations and distributions.

CERES Fast Longwave And SHortwave Radiative Flux (FLASHFlux) Version4A.

NASA Astrophysics Data System (ADS)

Sawaengphokhai, P.; Stackhouse, P. W., Jr.; Kratz, D. P.; Gupta, S. K.

2017-12-01

The agricultural, renewable energy management, and science communities need global surface and top-of-atmosphere (TOA) radiative fluxes on a low latency basis. The Clouds and Earth's Radiant Energy System (CERES) FLASHFlux (Fast Longwave and SHortwave radiative Flux) data products address this need by enhancing the speed of CERES processing using simplified calibration and parameterized model of surface fluxes to provide a daily global radiative fluxes data set within one week of satellite observations. The CERES FLASHFlux provides two data products: 1) an overpass swath Level 2 Single Scanner Footprint (SSF) data products separately for both Aqua and Terra observations, and 2) a daily Level 3 Time Interpolated and Spatially Averaged (TISA) 1o x 1o gridded data that combines Aqua and Terra observations. The CERES FLASHFlux data product is being promoted to Version4A. Updates to FLASHFlux Version4A include a new cloud retrieval algorithm and an improved shortwave surface flux parameterization. We inter-compared FLASHFlux Version4A, FLASHFlux Version3C, CERES Edition 4 Syn1Deg and at the monthly scale CERES Edition4 EBAF (Energy Balanced and Filled) Top-of-Atmosphere and Edition 4 Surface EBAF fluxes to evaluate these improvements. We also analyze the impact of the new inputs and cloud algorithm to the surface shortwave and longwave radiative fluxes using ground sites measurement provided by CAVE (CERES/ARM Validation Experiment).

Translational MRI Volumetry with NeuroQuant: Effects of Version and Normative Data on Relationships with Memory Performance in Healthy Older Adults and Patients with Mild Cognitive Impairment.

PubMed

Stelmokas, Julija; Yassay, Lance; Giordani, Bruno; Dodge, Hiroko H; Dinov, Ivo D; Bhaumik, Arijit; Sathian, K; Hampstead, Benjamin M

2017-01-01

NeuroQuant (NQ) is a fully-automated program that overcomes several existing limitations in the clinical translation of MRI-derived volumetry. The current study characterized differences between the original (NQ1) and an updated NQ version (NQ2) by 1) replicating previously identified relationships between neuropsychological test performance and medial temporal lobe volumes, 2) evaluating the level of agreement between NQ versions, and 3) determining if the addition of NQ2 age-/sex-based z-scores hold greater clinical utility for prediction of memory impairment than standard percent of intracranial volume (% ICV) values. Sixty-seven healthy older adults and 65 mild cognitive impairment patients underwent structural MRI and completed cognitive testing, including the Immediate and Delayed Memory indices from the Repeatable Battery for the Assessment of Neuropsychological Status. Results generally replicated previous relationships between key medial temporal lobe regions and memory test performance, though comparison of NQ regions revealed statistically different values that were biased toward one version or the other depending on the region. NQ2 hippocampal z-scores explained additional variance in memory performance relative to % ICV values. Findings indicate that NQ1/2 medial temporal lobe volumes, especially age- and sex-based z-scores, hold clinical value, though caution is warranted when directly comparing volumes across NQ versions.

Simulation of modern climate with the new version of the INM RAS climate model

NASA Astrophysics Data System (ADS)

Volodin, E. M.; Mortikov, E. V.; Kostrykin, S. V.; Galin, V. Ya.; Lykosov, V. N.; Gritsun, A. S.; Diansky, N. A.; Gusev, A. V.; Yakovlev, N. G.

2017-03-01

The INMCM5.0 numerical model of the Earth's climate system is presented, which is an evolution from the previous version, INMCM4.0. A higher vertical resolution for the stratosphere is applied in the atmospheric block. Also, we raised the upper boundary of the calculating area, added the aerosol block, modified parameterization of clouds and condensation, and increased the horizontal resolution in the ocean block. The program implementation of the model was also updated. We consider the simulation of the current climate using the new version of the model. Attention is focused on reducing systematic errors as compared to the previous version, reproducing phenomena that could not be simulated correctly in the previous version, and modeling the problems that remain unresolved.

Guidelines for chemical peeling in Japan (3rd edition).

PubMed

2012-04-01

Chemical peeling may be defined as the therapies, procedures and techniques used for the treatment of certain cutaneous diseases or conditions, and for aesthetic improvement. The procedures include the application of one or more chemical agents to the skin. Chemical peeling has been very popular in both medical and aesthetic fields. Because neither its scientific background is well understood nor a systematic approach established, medical and social problems have taken place. This prompted us to establish and distribute a standard guideline of care for chemical peeling. Previous guidelines such as the 2001 and 2004 versions included minimum standards of care such as indications, chemicals, applications, and any associated precautions, including post-peeling care. The principles in this updated version of chemical peeling are as follows: (i) chemical peeling should be performed under the strict technical control and responsibility of a physician; (ii) the physician should have sufficient knowledge of the structure and physiology of the skin and subcutaneous tissues, and understand the mechanisms of wound-healing induced by chemical peeling; (iii) the physician should be board-certified in an appropriate specialty such as dermatology; and (iv) the ultimate judgment regarding the appropriateness of any specific chemical peeling procedure must be made by the physician while considering all standard therapeutic protocols, which should be presented to each individual patient. Keeping these concepts in mind, this new version of the guidelines includes a more scientific and detailed approach from the viewpoint of evidence-based medicine. © 2011 Japanese Dermatological Association.

Measuring attachment to life in old age: the Portuguese version of the Positive Valuation of Life Scale (Positive VOL).

PubMed

Araújo, Lia; Ribeiro, Oscar; Teixeira, Laetitia; Azevedo, Maria João; Jopp, Daniela S; Rott, Christoph; Paúl, Constança

2015-10-01

This study aims to present the psychometric properties of the Portuguese version of the Positive Valuation of Life Scale (Lawton et al. in J Aging Ment Healt 13:3-31, 2001). Sample included 207 community-dwelling elders (129 women; M Age = 77.2 years, SD = 7.5). The data collection included the translated and adapted Portuguese version of Positive Valuation of Life Scale, Life Satisfaction Index Z, Meaning in Life Questionnaire and Geriatric Depression Scale. From exploratory factor analysis, two factors emerged, existential beliefs and perceived control, explaining 49 % of the total variance. Both factors were positively related with meaning in life and life satisfaction and negatively related with depression (p < 0.05). The values obtained for internal consistency for the total scale and for each subscale were good (α > 0.75). The Portuguese version of Positive VOL Scale represents a reliable and valid measure to capture the subjective experience of attachment to one's life. The two-factor structure is an update to Lawton's previous work and in line with findings obtained in the USA (Dennis et al. in What is valuation of life for frail community-dwelling older adults: factor structure and criterion validity of the VOL, Thomas Jefferson University, Center for Applied Research on Aging and Health Research, 2005) and Japan (Nakagawa et al. in Shinrigaku Kenkyu 84:37-46, 2013). Future research is required to investigate VOL predictors and the potential changes toward the end of the life span.

Past Changes in the Vertical Distribution of Ozone Part 1: Measurement Techniques, Uncertainties and Availability

NASA Technical Reports Server (NTRS)

Hassler, B.; Petropavlovskikh, I.; Staehelin, J.; August, T.; Bhartia, P. K.; Clerbaux, C.; Degenstein, D.; Maziere, M. De; Dinelli, B. M.; Dudhia, A.;

Updating the Hippocratic Oath to include medicine's social contract.

PubMed

Cruess, Richard; Cruess, Sylvia

2014-01-01

It is widely understood that reciting a contemporary version of the Hippocratic Oath has two purposes. It constitutes a public commitment on the part of the prospective doctor to preserving the traditional values of the medical profession and to meeting the obligations expected of a doctor. It is also an important symbolic ritual in the process of professional identity formation. A portion of the 1964 version of the Hippocratic Oath is examined for its relevance to the current practice of medicine. Its closing paragraph reads: 'If I do not violate this oath, may I enjoy life and art, be respected while I live and remembered with affection thereafter. May I always act to preserve the finest traditions of my calling and may I long experience the joy of healing those who seek my help.' This is interpreted as representing the doctor's expectations of the practice of medicine: job satisfaction; status, and prestige. It also conveys the understanding that enjoying these benefits is contingent upon the doctor's adherence to the terms of the Oath. Our current understanding of the relationship between medicine and society is that a social contract exists under which members of the profession are granted a privileged position in society on the understanding that they will meet society's reasonable expectations. These expectations entail obligations not only to patients and to the profession, but to wider society. The Oath under consideration, which concentrates on medicine's obligations to patients and to the profession, does not adequately reflect its obligations to society. It is suggested that versions of the Hippocratic Oath used in the future should be updated to better reflect the obligations of both individual doctors and the medical profession to society. © 2013 John Wiley & Sons Ltd.

The study of isochoric subcritical water using power series: A potential of energy generation with ISCW reactor

NASA Astrophysics Data System (ADS)

Sangian, Hanny F.; Tunena, Mercyas; Pani, Sutaryono

2017-09-01

The present study was aimed to analyze the behaviors of PVT and Z of ISCW (isochoric subcritical water) condition using mathematical series. The data showed that the pressure extremely increased from 15 bars until 80 bars taking only a few seconds that was probably to generate energy. The study was initiated by formulating power series in term of P and T with parameters, a0, a1, a2, a3, a4, a5, a6, and a7 whereas they were solved by performing the fitting method. By employing that technique, parameters were obtained as follows: a0= 7.63x-6, a1=0.23K/bar, a2=0.0035K2/bar2, a3=0.0068 K3/bar3, a4=8.27x10-7K4/bar4, a5=1.33x10-7K5/bar5, a6=2.18x10-8K6/bar6, and a7=3.64x10-9K7/bar7. Compressibility factor increased as pressure and temperature improved. In an isochoric condition, there was extremity that was located at a temperature above 450K in which compressibility factor abruptly increased with the tangent of the line was infinity. All parameters attaching on terms of a mathematical model proposed were assumed constant during P and T increase. At the request of the authors of the paper and with the agreement of the proceedings editor, an updated version of this article was published on 4 October 2017. The original version supplied to AIP Publishing included an incorrect spelling in the name of the first author. This has been corrected in the updated and re-published version.

The Canadian critical care nutrition guidelines in 2013: an update on current recommendations and implementation strategies.

PubMed

Dhaliwal, Rupinder; Cahill, Naomi; Lemieux, Margot; Heyland, Daren K

2014-02-01

Clinical practice guidelines (CPGs) are systematically developed statements to assist practitioners and patient decisions about appropriate healthcare for specific clinical circumstances, and are designed to minimize practice variation, improve costs, and improve clinical outcomes. The Canadian Critical Care Practice Guidelines (CCPGs) were first published in 2003 and most recently updated in 2013. A total of 68 new randomized controlled trials were identified since the last version in 2009, 50 of them published between 2009 and 2013. The remaining articles were trials published before 2009 but were not identified in previous iterations of the CCPGs. For clinical practice guidelines to be useful to practitioners, they need to be up-to-date and be reflective of the current body of evidence. Herein we describe the process by which the CCPGs were updated. This process resulted in 10 new sections or clinical topics. Of the old clinical topics, 3 recommendations were upgraded, 4 were downgraded, and 27 remained the same. To influence decision making at the bedside, these updated guidelines need to be accompanied by active guideline implementation strategies. Optimal implementation strategies should be guided by local contextual factors including barriers and facilitators to best practice recommendations. Moreover, evaluating and monitoring performance, such as participating in the International Nutrition Survey of practice, should be part of any intensive care unit's performance improvement strategy. The active implementation of the updated CCPGs may lead to better nutrition care and improved patient outcomes in the critical care setting.

Update of the Dutch manual for costing studies in health care

PubMed Central

Kanters, Tim A.; Bouwmans, Clazien A. M.; van der Linden, Naomi; Tan, Siok Swan; Hakkaart-van Roijen, Leona

2017-01-01

Objectives Dutch health economic guidelines include a costing manual, which describes preferred research methodology for costing studies and reference prices to ensure high quality studies and comparability between study outcomes. This paper describes the most important revisions of the costing manual compared to the previous version. Methods An online survey was sent out to potential users of the costing manual to identify topics for improvement. The costing manual was aligned with contemporary health economic guidelines. All methodology sections and parameter values needed for costing studies, particularly reference prices, were updated. An expert panel of health economists was consulted several times during the review process. The revised manual was reviewed by two members of the expert panel and by reviewers of the Dutch Health Care Institute. Results The majority of survey respondents was satisfied with content and usability of the existing costing manual. Respondents recommended updating reference prices and adding some particular commonly needed reference prices. Costs categories were adjusted to the international standard: 1) costs within the health care sector; 2) patient and family costs; and 3) costs in other sectors. Reference prices were updated to reflect 2014 values. The methodology chapter was rewritten to match the requirements of the costing manual and preferences of the users. Reference prices for nursing days of specific wards, for diagnostic procedures and nurse practitioners were added. Conclusions The usability of the costing manual was increased and parameter values were updated. The costing manual became integrated in the new health economic guidelines. PMID:29121647

Update of the Dutch manual for costing studies in health care.

PubMed

Kanters, Tim A; Bouwmans, Clazien A M; van der Linden, Naomi; Tan, Siok Swan; Hakkaart-van Roijen, Leona

2017-01-01

Dutch health economic guidelines include a costing manual, which describes preferred research methodology for costing studies and reference prices to ensure high quality studies and comparability between study outcomes. This paper describes the most important revisions of the costing manual compared to the previous version. An online survey was sent out to potential users of the costing manual to identify topics for improvement. The costing manual was aligned with contemporary health economic guidelines. All methodology sections and parameter values needed for costing studies, particularly reference prices, were updated. An expert panel of health economists was consulted several times during the review process. The revised manual was reviewed by two members of the expert panel and by reviewers of the Dutch Health Care Institute. The majority of survey respondents was satisfied with content and usability of the existing costing manual. Respondents recommended updating reference prices and adding some particular commonly needed reference prices. Costs categories were adjusted to the international standard: 1) costs within the health care sector; 2) patient and family costs; and 3) costs in other sectors. Reference prices were updated to reflect 2014 values. The methodology chapter was rewritten to match the requirements of the costing manual and preferences of the users. Reference prices for nursing days of specific wards, for diagnostic procedures and nurse practitioners were added. The usability of the costing manual was increased and parameter values were updated. The costing manual became integrated in the new health economic guidelines.

PC-SPES (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about the use of PC-SPES as a treatment for prostate cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

Hydrazine Sulfate (PDQ®)—Patient Version

Cancer.gov

Expert-reviewed information summary about the use of hydrazine sulfate as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

PC-SPES (PDQ®)—Patient Version

Cancer.gov

Expert-reviewed information summary about the use of PC-SPES as a treatment for prostate cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

2005 v4.2 Technical Support Document

EPA Pesticide Factsheets

Technical Support Document for the Final Transport Rule describes how updated 2005 NEI, version 2 emissions and were processed for air quality modeling in support of the Cross-state Air Pollution Rule (CSAPR).

SAGE II Version 7.00 Release

Atmospheric Science Data Center

2013-07-10

... channel due to uncertainty in the H2O spectroscopy in this spectral band Updated our estimation of the SAGE II water vapor channel filter location drift resulting in better agreement with more modern datasets ...

Salivary gland tumors

MedlinePlus

... BH, Lund V, et al, eds. Cummings Otolaryngology: Head & Neck Surgery . 6th ed. Philadelphia, PA: Elsevier Saunders; 2015: ... PDQ) - health professional version. www.cancer.gov/types/head-and-neck/hp/adult/salivary-gland-treatment-pdq . Updated January ...

The Pfam protein families database

PubMed Central

Finn, Robert D.; Mistry, Jaina; Tate, John; Coggill, Penny; Heger, Andreas; Pollington, Joanne E.; Gavin, O. Luke; Gunasekaran, Prasad; Ceric, Goran; Forslund, Kristoffer; Holm, Liisa; Sonnhammer, Erik L. L.; Eddy, Sean R.; Bateman, Alex

2010-01-01

Pfam is a widely used database of protein families and domains. This article describes a set of major updates that we have implemented in the latest release (version 24.0). The most important change is that we now use HMMER3, the latest version of the popular profile hidden Markov model package. This software is ∼100 times faster than HMMER2 and is more sensitive due to the routine use of the forward algorithm. The move to HMMER3 has necessitated numerous changes to Pfam that are described in detail. Pfam release 24.0 contains 11 912 families, of which a large number have been significantly updated during the past two years. Pfam is available via servers in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/). PMID:19920124

LARCRIM user's guide, version 1.0

NASA Technical Reports Server (NTRS)

Davis, John S.; Heaphy, William J.

1993-01-01

LARCRIM is a relational database management system (RDBMS) which performs the conventional duties of an RDBMS with the added feature that it can store attributes which consist of arrays or matrices. This makes it particularly valuable for scientific data management. It is accessible as a stand-alone system and through an application program interface. The stand-alone system may be executed in two modes: menu or command. The menu mode prompts the user for the input required to create, update, and/or query the database. The command mode requires the direct input of LARCRIM commands. Although LARCRIM is an update of an old database family, its performance on modern computers is quite satisfactory. LARCRIM is written in FORTRAN 77 and runs under the UNIX operating system. Versions have been released for the following computers: SUN (3 & 4), Convex, IRIS, Hewlett-Packard, CRAY 2 & Y-MP.

The Community WRF-Hydro Modeling System Version 4 Updates: Merging Toward Capabilities of the National Water Model

NASA Astrophysics Data System (ADS)

McAllister, M.; Gochis, D.; Dugger, A. L.; Karsten, L. R.; McCreight, J. L.; Pan, L.; Rafieeinasab, A.; Read, L. K.; Sampson, K. M.; Yu, W.

2017-12-01

The community WRF-Hydro modeling system is publicly available and provides researchers and operational forecasters a flexible and extensible capability for performing multi-scale, multi-physics options for hydrologic modeling that can be run independent or fully-interactive with the WRF atmospheric model. The core WRF-Hydro physics model contains very high-resolution descriptions of terrestrial hydrologic process representations such as land-atmosphere exchanges of energy and moisture, snowpack evolution, infiltration, terrain routing, channel routing, basic reservoir representation and hydrologic data assimilation. Complementing the core physics components of WRF-Hydro are an ecosystem of pre- and post-processing tools that facilitate the preparation of terrain and meteorological input data, an open-source hydrologic model evaluation toolset (Rwrfhydro), hydrologic data assimilation capabilities with DART and advanced model visualization capabilities. The National Center for Atmospheric Research (NCAR), through collaborative support from the National Science Foundation and other funding partners, provides community support for the entire WRF-Hydro system through a variety of mechanisms. This presentation summarizes the enhanced user support capabilities that are being developed for the community WRF-Hydro modeling system. These products and services include a new website, open-source code repositories, documentation and user guides, test cases, online training materials, live, hands-on training sessions, an email list serve, and individual user support via email through a new help desk ticketing system. The WRF-Hydro modeling system and supporting tools which now include re-gridding scripts and model calibration have recently been updated to Version 4 and are merging toward capabilities of the National Water Model.

Smithsonian Astrophysical Observatory (SAO) star catalog (Sao staff 1966, edition ADC 1989): Documentation for the machine-readable version

NASA Technical Reports Server (NTRS)

Roman, Nancy G.; Warren, Wayne H., Jr.

1989-01-01

An updated, corrected, and extended machine readable version of the catalog is described. Published and unpublished errors discovered in the previous version were corrected, and multiple star and supplemental BD identifications were added to stars where more than one SAO entry has the same Durchmusterung number. Henry Draper Extension (HDE) numbers were added for stars found in both volumes of the extension. Data for duplicate SAO entries (those referring to the same star) were flagged. J2000 positions in usual units and in radians were added.

Static Chemistry in Disks or Clouds

NASA Astrophysics Data System (ADS)

Semenov, D.; Wiebe, D.

2006-11-01

This FORTRAN77 code can be used to model static, time-dependent chemistry in ISM and circumstellar disks. Current version is based on the OSU'06 gas-grain astrochemical network with all updates to the reaction rates, and includes surface chemistry from Hasegawa & Herbst (1993) and Hasegawa, Herbst, and Leung (1992). Surface chemistry can be modeled either with the standard rate equation approach or modified rate equation approach (useful in disks). Gas-grain interactions include sticking of neutral molecules to grains, dissociative recombination of ions on grains as well as thermal, UV, X-ray, and CRP-induced desorption of frozen species. An advanced X-ray chemistry and 3 grain sizes with power-law size distribution are also included. An deuterium extension to this chemical model is available.

GRID3D-v2: An updated version of the GRID2D/3D computer program for generating grid systems in complex-shaped three-dimensional spatial domains

NASA Technical Reports Server (NTRS)

Steinthorsson, E.; Shih, T. I-P.; Roelke, R. J.

1991-01-01

In order to generate good quality systems for complicated three-dimensional spatial domains, the grid-generation method used must be able to exert rather precise controls over grid-point distributions. Several techniques are presented that enhance control of grid-point distribution for a class of algebraic grid-generation methods known as the two-, four-, and six-boundary methods. These techniques include variable stretching functions from bilinear interpolation, interpolating functions based on tension splines, and normalized K-factors. The techniques developed in this study were incorporated into a new version of GRID3D called GRID3D-v2. The usefulness of GRID3D-v2 was demonstrated by using it to generate a three-dimensional grid system in the coolent passage of a radial turbine blade with serpentine channels and pin fins.

ChEMBL web services: streamlining access to drug discovery data and utilities

PubMed Central

Davies, Mark; Nowotka, Michał; Papadatos, George; Dedman, Nathan; Gaulton, Anna; Atkinson, Francis; Bellis, Louisa; Overington, John P.

2015-01-01

ChEMBL is now a well-established resource in the fields of drug discovery and medicinal chemistry research. The ChEMBL database curates and stores standardized bioactivity, molecule, target and drug data extracted from multiple sources, including the primary medicinal chemistry literature. Programmatic access to ChEMBL data has been improved by a recent update to the ChEMBL web services (version 2.0.x, https://www.ebi.ac.uk/chembl/api/data/docs), which exposes significantly more data from the underlying database and introduces new functionality. To complement the data-focused services, a utility service (version 1.0.x, https://www.ebi.ac.uk/chembl/api/utils/docs), which provides RESTful access to commonly used cheminformatics methods, has also been concurrently developed. The ChEMBL web services can be used together or independently to build applications and data processing workflows relevant to drug discovery and chemical biology. PMID:25883136

Software for biomedical engineering signal processing laboratory experiments.

PubMed

Tompkins, Willis J; Wilson, J

2009-01-01

In the early 1990's we developed a special computer program called UW DigiScope to provide a mechanism for anyone interested in biomedical digital signal processing to study the field without requiring any other instrument except a personal computer. There are many digital filtering and pattern recognition algorithms used in processing biomedical signals. In general, students have very limited opportunity to have hands-on access to the mechanisms of digital signal processing. In a typical course, the filters are designed non-interactively, which does not provide the student with significant understanding of the design constraints of such filters nor their actual performance characteristics. UW DigiScope 3.0 is the first major update since version 2.0 was released in 1994. This paper provides details on how the new version based on MATLAB! works with signals, including the filter design tool that is the programming interface between UW DigiScope and processing algorithms.

Enhancements to the caliop aerosol subtyping and lidar ratio selection algorithms for level II version 4

NASA Astrophysics Data System (ADS)

Omar, A.; Tackett, J.; Kim, M.-H.; Vaughan, M.; Kar, J.; Trepte, C.; Winker, D.

2018-04-01

Several enhancements have been implemented for the version 4 aerosol subtyping and lidar ratio selection algorithms of Cloud Aerosol Lidar with Orthogonal Polarization (CALIOP). Version 4 eliminates the confusion between smoke and clean marine aerosols seen in version 3 by modifications to the elevated layer flag definitions used to identify smoke aerosols over the ocean. To differentiate between mixtures of dust and smoke, and dust and marine aerosols, a new aerosol type will be added in the version 4 data products. In the marine boundary layer, moderately depolarizing aerosols are no longer modeled as mixtures of dust and smoke (polluted dust) but rather as mixtures of dust and seasalt (dusty marine). Some lidar ratios have been updated in the version 4 algorithms. In particular, the dust lidar ratios have been adjusted to reflect the latest measurements and model studies.

Updated System-Availability and Resource-Allocation Program

NASA Technical Reports Server (NTRS)

Viterna, Larry

2004-01-01

A second version of the Availability, Cost and Resource Allocation (ACARA) computer program has become available. The first version was reported in an earlier tech brief. To recapitulate: ACARA analyzes the availability, mean-time-between-failures of components, life-cycle costs, and scheduling of resources of a complex system of equipment. ACARA uses a statistical Monte Carlo method to simulate the failure and repair of components while complying with user-specified constraints on spare parts and resources. ACARA evaluates the performance of the system on the basis of a mathematical model developed from a block-diagram representation. The previous version utilized the MS-DOS operating system and could not be run by use of the most recent versions of the Windows operating system. The current version incorporates the algorithms of the previous version but is compatible with Windows and utilizes menus and a file-management approach typical of Windows-based software.

Child-rearing ability and the provision of fertility services: an Ethics Committee opinion.

PubMed

2017-12-01

Fertility programs may withhold services from prospective patients on the basis of well-grounded reasons that those patients will be unable to provide minimally adequate or safe care for offspring. This document was reviewed and updated; this version replaces the previous version of this document, last published July 2013 (Fertil Steril 2013;100:50-53). Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

NASA Glenn Steady-State Heat Pipe Code GLENHP: Compilation for 64- and 32-Bit Windows Platforms

NASA Technical Reports Server (NTRS)

Tower, Leonard K.; Geng, Steven M.

2016-01-01

A new version of the NASA Glenn Steady State Heat Pipe Code, designated "GLENHP," is introduced here. This represents an update to the disk operating system (DOS) version LERCHP reported in NASA/TM-2000-209807. The new code operates on 32- and 64-bit Windows-based platforms from within the 32-bit command prompt window. An additional evaporator boundary condition and other features are provided.

Avionics Tether Operations Control

NASA Technical Reports Server (NTRS)

Glaese, John R.

2001-01-01

The activities described in this Final Report were authorized and performed under Purchase Order Number H32835D, issued as part of NASA contract number NAS8-00114. The period of performance of this PO was from March 1 to September 30, 2001. The primary work activity was the continued development and updating of the tether dynamic simulation tools GTOSS (Generalized Tethered Object System Simulation) and TSSIM (Tethered Satellite System) and use of these and other tools in the analysis of various tether dynamics problems. Several updated versions of GTOSS were delivered during the period of performance by the author of the simulation, Lang Associates' David Lang. These updates had mainly to do with updated documentation and an updated coordinate system definition to the J2000 standards. This Final Report is organized by the months in which the activities described were performed. The following sections review the Statement of Work (SOW) and activities performed to satisfy it.

FreeSolv: A database of experimental and calculated hydration free energies, with input files

PubMed Central

Mobley, David L.; Guthrie, J. Peter

2014-01-01

This work provides a curated database of experimental and calculated hydration free energies for small neutral molecules in water, along with molecular structures, input files, references, and annotations. We call this the Free Solvation Database, or FreeSolv. Experimental values were taken from prior literature and will continue to be curated, with updated experimental references and data added as they become available. Calculated values are based on alchemical free energy calculations using molecular dynamics simulations. These used the GAFF small molecule force field in TIP3P water with AM1-BCC charges. Values were calculated with the GROMACS simulation package, with full details given in references cited within the database itself. This database builds in part on a previous, 504-molecule database containing similar information. However, additional curation of both experimental data and calculated values has been done here, and the total number of molecules is now up to 643. Additional information is now included in the database, such as SMILES strings, PubChem compound IDs, accurate reference DOIs, and others. One version of the database is provided in the Supporting Information of this article, but as ongoing updates are envisioned, the database is now versioned and hosted online. In addition to providing the database, this work describes its construction process. The database is available free-of-charge via http://www.escholarship.org/uc/item/6sd403pz. PMID:24928188

Update of GRASP/Ada reverse engineering tools for Ada

NASA Technical Reports Server (NTRS)

Cross, James H., II

1993-01-01

The GRASP/Ada project (Graphical Representations of Algorithms, Structures, and Processes for Ada) successfully created and prototyped a new algorithmic level graphical representation for Ada software, the Control Structure Diagram (CSD). The primary impetus for creation of the CSD was to improve the comprehension efficiency of Ada software and, as a result, improve reliability and reduce costs. The emphasis was on the automatic generation of the CSD from Ada PDL or source code to support reverse engineering and maintenance. The CSD has the potential to replace traditional pretty printed Ada source code. In Phase 1 of the GRASP/Ada project, the CSD graphical constructs were created and applied manually to several small Ada programs. A prototype CSD generator (Version 1) was designed and implemented using FLEX and BISON running under VMS on a VAX 11-780. In Phase 2, the prototype was improved and ported to the Sun 4 platform under UNIX. A user interface was designed and partially implemented using the HP widget toolkit and the X Windows System. In Phase 3, the user interface was extensively reworked using the Athena widget toolkit and X Windows. The prototype was applied successfully to numerous Ada programs ranging in size from several hundred to several thousand lines of source code. Following Phase 3,e two update phases were completed. Update'92 focused on the initial analysis of evaluation data collected from software engineering students at Auburn University and the addition of significant enhancements to the user interface. Update'93 (the current update) focused on the statistical analysis of the data collected in the previous update and preparation of Version 3.4 of the prototype for limited distribution to facilitate further evaluation. The current prototype provides the capability for the user to generate CSD's from Ada PDL or source code in a reverse engineering as well as forward engineering mode with a level of flexibility suitable for practical application. An overview of the GRASP/Ada project with an emphasis on the current update is provided.

miRanalyzer: an update on the detection and analysis of microRNAs in high-throughput sequencing experiments

PubMed Central

Hackenberg, Michael; Rodríguez-Ezpeleta, Naiara; Aransay, Ana M.

2011-01-01

We present a new version of miRanalyzer, a web server and stand-alone tool for the detection of known and prediction of new microRNAs in high-throughput sequencing experiments. The new version has been notably improved regarding speed, scope and available features. Alignments are now based on the ultrafast short-read aligner Bowtie (granting also colour space support, allowing mismatches and improving speed) and 31 genomes, including 6 plant genomes, can now be analysed (previous version contained only 7). Differences between plant and animal microRNAs have been taken into account for the prediction models and differential expression of both, known and predicted microRNAs, between two conditions can be calculated. Additionally, consensus sequences of predicted mature and precursor microRNAs can be obtained from multiple samples, which increases the reliability of the predicted microRNAs. Finally, a stand-alone version of the miRanalyzer that is based on a local and easily customized database is also available; this allows the user to have more control on certain parameters as well as to use specific data such as unpublished assemblies or other libraries that are not available in the web server. miRanalyzer is available at http://bioinfo2.ugr.es/miRanalyzer/miRanalyzer.php. PMID:21515631

DIY Solar Market Analysis Webinar Series: PVWatts® | State, Local, and

Science.gov Websites

, and updates the energy prediction algorithms to be in line with the actual performance of modern the latest update." In this webinar, one of the tool's developers explains how the new version of ® Wednesday, July 9, 2014 As part of a Do-It-Yourself Solar Market Analysis summer series, NREL's Solar

CyanoBase: the cyanobacteria genome database update 2010.

PubMed

Nakao, Mitsuteru; Okamoto, Shinobu; Kohara, Mitsuyo; Fujishiro, Tsunakazu; Fujisawa, Takatomo; Sato, Shusei; Tabata, Satoshi; Kaneko, Takakazu; Nakamura, Yasukazu

2010-01-01

CyanoBase (http://genome.kazusa.or.jp/cyanobase) is the genome database for cyanobacteria, which are model organisms for photosynthesis. The database houses cyanobacteria species information, complete genome sequences, genome-scale experiment data, gene information, gene annotations and mutant information. In this version, we updated these datasets and improved the navigation and the visual display of the data views. In addition, a web service API now enables users to retrieve the data in various formats with other tools, seamlessly.

Cancell/Cantron/Protocel (PDQ®)—Patient Version

Cancer.gov

Expert-reviewed information summary about the use of Cancell/Entelev as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

714-X (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about the use of 714-X as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

NONROAD Emissions Inventory Model Installation

EPA Pesticide Factsheets

This release and the very limited documentation presented here are intended for users already familiar with an earlier release of the NONROAD model. NONROAD2008 is major update and it supersedes all previous versions, most recently NONROAD2005.

Rare Earth Element Geochemistry for Produced Waters, WY

DOE Data Explorer

Quillinan, Scott; Nye, Charles; McLing, Travis; Neupane, Hari

2016-06-30

These data represent major, minor, trace, isotopes, and rare earth element concentrations in geologic formations and water associated with oil and gas production. *Note - Link below contains updated version of spreadsheet (6/14/2017)

Cargo liability regimes

DOT National Transportation Integrated Search

2001-01-01

There are at present at least three international regimes of maritime cargo liability in force in different countries of the world - the original Hague rules (1924), the updated version known as the Hague-Visby rules (1968, further amended 1979), and...

RMP*eSubmit User's Manual

EPA Pesticide Factsheets

RMP*eSubmit facilitates secure online Risk Management Plan updates/resubmissions, required at least every 5 years. Reporting requirements have not changed since 2004, but the 2012 version of North American Industry Classification System has been integrated

Gerson Therapy (PDQ®)—Patient Version

Cancer.gov

Expert-reviewed information summary about the use of the Gerson therapy as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

--No Title--

Science.gov Websites

Version] Short Range Forecast Discussion NWS Weather Prediction Center College Park MD 337 PM EDT Sun May available at www.wpc.ncep.noaa.gov/basicwx/basicwx_ndfd.php Last Updated: 337 PM EDT Sun May 27 2018

Hydrazine Sulfate (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about the use of hydrazine sulfate as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

National Counterdrug Center (NCC) Simulation System Operational Requirements Document (ORD) Version 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holter, Gregory M

2001-01-26

This Operational Requirements Document (ORD) describes the capabilities that need to be incorporated in the NCC interactive simulation system being developed under the auspices of the NCC development program. The ORD addresses the necessary capabilities (i.e. what the system needs to be able to do); it defines the envelope of situations and circumstances that the NCC system must be able to represent and operate within. The NCC system will be developed in modules over a period of several years. This ORD, Version 2, supersedes the previous version. Future updates of this ORD are anticipated to be issued as needed tomore » guide the development of later versions of the NCC system.« less

A user's guide to Sandia's latin hypercube sampling software : LHS UNIX library/standalone version.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swiler, Laura Painton; Wyss, Gregory Dane

2004-07-01

This document is a reference guide for the UNIX Library/Standalone version of the Latin Hypercube Sampling Software. This software has been developed to generate Latin hypercube multivariate samples. This version runs on Linux or UNIX platforms. This manual covers the use of the LHS code in a UNIX environment, run either as a standalone program or as a callable library. The underlying code in the UNIX Library/Standalone version of LHS is almost identical to the updated Windows version of LHS released in 1998 (SAND98-0210). However, some modifications were made to customize it for a UNIX environment and as a librarymore » that is called from the DAKOTA environment. This manual covers the use of the LHS code as a library and in the standalone mode under UNIX.« less

Subsonic Ultra Green Aircraft Research. Phase II - Volume I; Truss Braced Wing Design Exploration

NASA Technical Reports Server (NTRS)

Bradley, Marty K.; Droney, Christopher K.; Allen, Timothy J.

2015-01-01

This report summarizes the Truss Braced Wing (TBW) work accomplished by the Boeing Subsonic Ultra Green Aircraft Research (SUGAR) team, consisting of Boeing Research and Technology, Boeing Commercial Airplanes, General Electric, Georgia Tech, Virginia Tech, NextGen Aeronautics, and Microcraft. A multi-disciplinary optimization (MDO) environment defined the geometry that was further refined for the updated SUGAR High TBW configuration. Airfoil shapes were tested in the NASA TCT facility, and an aeroelastic model was tested in the NASA TDT facility. Flutter suppression was successfully demonstrated using control laws derived from test system ID data and analysis models. Aeroelastic impacts for the TBW design are manageable and smaller than assumed in Phase I. Flutter analysis of TBW designs need to include pre-load and large displacement non-linear effects to obtain a reasonable match to test data. With the updated performance and sizing, fuel burn and energy use is reduced by 54% compared to the SUGAR Free current technology Baseline (Goal 60%). Use of the unducted fan version of the engine reduces fuel burn and energy by 56% compared to the Baseline. Technology development roadmaps were updated, and an airport compatibility analysis established feasibility of a folding wing aircraft at existing airports.

Evolution of cooperation driven by incremental learning

NASA Astrophysics Data System (ADS)

Li, Pei; Duan, Haibin

2015-02-01

It has been shown that the details of microscopic rules in structured populations can have a crucial impact on the ultimate outcome in evolutionary games. So alternative formulations of strategies and their revision processes exploring how strategies are actually adopted and spread within the interaction network need to be studied. In the present work, we formulate the strategy update rule as an incremental learning process, wherein knowledge is refreshed according to one's own experience learned from the past (self-learning) and that gained from social interaction (social-learning). More precisely, we propose a continuous version of strategy update rules, by introducing the willingness to cooperate W, to better capture the flexibility of decision making behavior. Importantly, the newly gained knowledge including self-learning and social learning is weighted by the parameter ω, establishing a strategy update rule involving innovative element. Moreover, we quantify the macroscopic features of the emerging patterns to inspect the underlying mechanisms of the evolutionary process using six cluster characteristics. In order to further support our results, we examine the time evolution course for these characteristics. Our results might provide insights for understanding cooperative behaviors and have several important implications for understanding how individuals adjust their strategies under real-life conditions.

Bernese motive and goal inventory in exercise and sport: Validation of an updated version of the questionnaire.

PubMed

Schmid, Julia; Gut, Vanessa; Conzelmann, Achim; Sudeck, Gorden

2018-01-01

Target group-specific intervention strategies are often called for in order to effectively promote exercise and sport. Currently, motives and goals are rarely included systematically in the design of interventions, despite the key role they play in well-being and adherence to exercise. The Bernese motive and goal inventory (BMZI) allows an individual diagnosis of motives and goals in exercise and sport in people in middle adulthood. The purpose of the present study was to elaborate on the original BMZI and to modify the questionnaire in order to improve its psychometric properties. The study is based on data from two samples (sample A: 448 employees of companies and authorities; sample B: 853 patients of a medical rehabilitation programme). We applied confirmatory factor analysis and exploratory structural equation modelling. Overall, both the original and the updated BMZI had an acceptable to good validity and a good reliability. However, the revised questionnaire had slightly better reliability. The updated BMZI consists of 23 items and covers the following motives and goals: Body/Appearance, Contact, Competition/Performance, Aesthetics, Distraction/Catharsis, Fitness and Health. It is recommended as an economical inventory for the individual diagnosis of important psychological conditions for exercise and sport.

Results from CrIS/ATMS Obtained Using an AIRS "Version-6 Like" Retrieval Algorithm

NASA Technical Reports Server (NTRS)

Susskind, Joel; Kouvaris, Louis; Iredell, Lena

2015-01-01

We have tested and evaluated Version-6.22 AIRS and Version-6.22 CrIS products on a single day, December 4, 2013, and compared results to those derived using AIRS Version-6. AIRS and CrIS Version-6.22 O3(p) and q(p) products are both superior to those of AIRS Version-6All AIRS and CrIS products agree reasonably well with each other CrIS Version-6.22 T(p) and q(p) results are slightly poorer than AIRS under very cloudy conditions. Both AIRS and CrIS Version-6.22 run now at JPL. Our short term plans are to analyze many common months at JPL in the near future using Version-6.22 or a further improved algorithm to assess the compatibility of AIRS and CrIS monthly mean products and their interannual differencesUpdates to the calibration of both CrIS and ATMS are still being finalized. JPL plans, in collaboration with the Goddard DISC, to reprocess all AIRS data using a still to be finalized Version-7 retrieval algorithm, and to reprocess all recalibrated CrISATMS data using Version-7 as well.

Results from CrIS/ATMS Obtained Using an AIRS "Version-6 like" Retrieval Algorithm

NASA Technical Reports Server (NTRS)

Susskind, Joel; Kouvaris, Louis; Iredell, Lena

2015-01-01

We tested and evaluated Version-6.22 AIRS and Version-6.22 CrIS products on a single day, December 4, 2013, and compared results to those derived using AIRS Version-6. AIRS and CrIS Version-6.22 O3(p) and q(p) products are both superior to those of AIRS Version-6All AIRS and CrIS products agree reasonably well with each other. CrIS Version-6.22 T(p) and q(p) results are slightly poorer than AIRS over land, especially under very cloudy conditions. Both AIRS and CrIS Version-6.22 run now at JPL. Our short term plans are to analyze many common months at JPL in the near future using Version-6.22 or a further improved algorithm to assess the compatibility of AIRS and CrIS monthly mean products and their interannual differences. Updates to the calibration of both CrIS and ATMS are still being finalized. JPL plans, in collaboration with the Goddard DISC, to reprocess all AIRS data using a still to be finalized Version-7 retrieval algorithm, and to reprocess all recalibrated CrISATMS data using Version-7 as well.

SMMP v. 3.0—Simulating proteins and protein interactions in Python and Fortran

NASA Astrophysics Data System (ADS)

Meinke, Jan H.; Mohanty, Sandipan; Eisenmenger, Frank; Hansmann, Ulrich H. E.

2008-03-01

We describe a revised and updated version of the program package SMMP. SMMP is an open-source FORTRAN package for molecular simulation of proteins within the standard geometry model. It is designed as a simple and inexpensive tool for researchers and students to become familiar with protein simulation techniques. SMMP 3.0 sports a revised API increasing its flexibility, an implementation of the Lund force field, multi-molecule simulations, a parallel implementation of the energy function, Python bindings, and more. Program summaryTitle of program:SMMP Catalogue identifier:ADOJ_v3_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADOJ_v3_0.html Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Licensing provisions:Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html Programming language used:FORTRAN, Python No. of lines in distributed program, including test data, etc.:52 105 No. of bytes in distributed program, including test data, etc.:599 150 Distribution format:tar.gz Computer:Platform independent Operating system:OS independent RAM:2 Mbytes Classification:3 Does the new version supersede the previous version?:Yes Nature of problem:Molecular mechanics computations and Monte Carlo simulation of proteins. Solution method:Utilizes ECEPP2/3, FLEX, and Lund potentials. Includes Monte Carlo simulation algorithms for canonical, as well as for generalized ensembles. Reasons for new version:API changes and increased functionality. Summary of revisions:Added Lund potential; parameters used in subroutines are now passed as arguments; multi-molecule simulations; parallelized energy calculation for ECEPP; Python bindings. Restrictions:The consumed CPU time increases with the size of protein molecule. Running time:Depends on the size of the simulated molecule.

Online Particle Physics Information

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kreitz, Patricia A

2003-04-24

This list describes a broad set of online resources that are of value to the particle physics community. It is prescreened and highly selective. It describes the scope, size, and organization of the resources so that efficient choices can be made amongst many sites which may appear similar. A resource is excluded if it provides information primarily of interest to only one institution. Because this list must be fixed in print, it is important to consult the updated version of this compilation which includes newly added resources and hypertext links to more complete information at: http://www.slac.stanford.edu/library/pdg/.

Performance study of SKIROC2/A ASIC for ILD Si-W ECAL

NASA Astrophysics Data System (ADS)

Suehara, T.; Sekiya, I.; Callier, S.; Balagura, V.; Boudry, V.; Brient, J.-C.; de la Taille, C.; Kawagoe, K.; Irles, A.; Magniette, F.; Nanni, J.; Pöschl, R.; Yoshioka, T.

2018-03-01

The ILD Si-W ECAL is a sampling calorimeter with tungsten absorber and highly segmented silicon layers for the International Large Detector (ILD), one of the two detector concepts for the International Linear Collider. SKIROC2 is an ASIC for the ILD Si-W ECAL. To investigate the issues found in prototype detectors, we prepared dedicated ASIC evaluation boards with either BGA sockets or directly soldered SKIROC2. We report a performance study with the evaluation boards, including signal-to-noise ratio and TDC performance with comparing SKIROC2 and an updated version, SKIROC2A.

Glossary on the environmental impact of a nuclear war. Technical note

DOE Office of Scientific and Technical Information (OSTI.GOV)

Verstraete, M.M.

1986-02-01

The glossary defines a number of words, expressions, and acronyms used in the description of the impact of nuclear war on the environment, and associated issues. Selected additional words related to the problems of armaments, disarmament, and nuclear war in general were also added for convenience, although terms and expressions specifically related to the medical aspects of the problem were not included. The glossary is an enlarged and updated version of the glossary that was published as part of the SCOPE-Enuwar study on the same subject, and published by Wiley (Pittock et al., 1986).

5S ribosomal RNA database Y2K

PubMed Central

Szymanski, Maciej; Barciszewska, Miroslawa Z.; Barciszewski, Jan; Erdmann, Volker A.

2000-01-01

This paper presents the updated version (Y2K) of the database of ribosomal 5S ribonucleic acids (5S rRNA) and their genes (5S rDNA), http://rose.man/poznan. pl/5SData/index.html . This edition of the database contains 1985 primary structures of 5S rRNA and 5S rDNA. They include 60 archaebacterial, 470 eubacterial, 63 plastid, nine mitochondrial and 1383 eukaryotic sequences. The nucleotide sequences of the 5S rRNAs or 5S rDNAs are divided according to the taxonomic position of the source organisms. PMID:10592212

5S ribosomal RNA database Y2K.

PubMed

Szymanski, M; Barciszewska, M Z; Barciszewski, J; Erdmann, V A

2000-01-01

This paper presents the updated version (Y2K) of the database of ribosomal 5S ribonucleic acids (5S rRNA) and their genes (5S rDNA), http://rose.man/poznan.pl/5SData/index.html. This edition of the database contains 1985primary structures of 5S rRNA and 5S rDNA. They include 60 archaebacterial, 470 eubacterial, 63 plastid, nine mitochondrial and 1383 eukaryotic sequences. The nucleotide sequences of the 5S rRNAs or 5S rDNAs are divided according to the taxonomic position of the source organisms.

Perturbation theory of nuclear matter with a microscopic effective interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benhar, Omar; Lovato, Alessandro

Here, an updated and improved version of the effective interaction based on the Argonne-Urbana nuclear Hamiltonian, derived using the formalism of correlated basis functions and the cluster expansion technique, is employed to obtain a number of properties of cold nuclear matter at arbitrary neutron excess within the formalism of many-body perturbation theory. The numerical results, including the ground-state energy per nucleon, the symmetry energy, the pressure, the compressibility, and the single-particle spectrum, are discussed in the context of the available empirical information, obtained from measured nuclear properties and heavy-ion collisions.

Perturbation theory of nuclear matter with a microscopic effective interaction

DOE PAGES

Benhar, Omar; Lovato, Alessandro

2017-11-01

Here, an updated and improved version of the effective interaction based on the Argonne-Urbana nuclear Hamiltonian, derived using the formalism of correlated basis functions and the cluster expansion technique, is employed to obtain a number of properties of cold nuclear matter at arbitrary neutron excess within the formalism of many-body perturbation theory. The numerical results, including the ground-state energy per nucleon, the symmetry energy, the pressure, the compressibility, and the single-particle spectrum, are discussed in the context of the available empirical information, obtained from measured nuclear properties and heavy-ion collisions.

In Situ Dating Experiments of Igneous Rocks Using the KArLE Instrument: A Case Study for Approximately 380 Ma Basaltic Rocks

NASA Technical Reports Server (NTRS)

Cho, Yuichiro; Cohen, Barbara A.

2018-01-01

We report new K-Ar isochron data for two approximately 380 Ma basaltic rocks, using an updated version of the Potassium-Argon Laser Experiment (KArLE). These basalts have K contents comparable to lunar KREEP basalts or igneous lithologies found by Mars rovers, whereas previous proof-of-concept studies focused primarily on more K-rich rocks. We continue to measure these analogue samples to show the advancing capability of in situ K-Ar geochronology. KArLE is applicable to other bodies including the Moon or asteroids.

VizieR Online Data Catalog: OCARS catalog second version (Malkin, 2016)

NASA Astrophysics Data System (ADS)

Malkin, Z. M.

2016-11-01

Unlike the first version, supported in 2007-2015, the second version of the OCARS catalog includes three files: ocars.txt is the main file containing the source coordinates, source types, redshifts, and approximate magnitudes, together with commentary; this file corresponds to the first version of the OCARS catalog; ocars_m.txt contains photometric data in the 13 uUBgV rRiIzJHK bands; ocars_n.txt contains a table of corresponding source names in various catalogs; currently, only cross-identifications with IVS programs4 and the LQAC catalog [9] are included; The list of objects included in the OCARS catalog is formed from various astrometric and geodeticVLBI programs and catalogs in the following order: - sources in the ICRF2 [2]; - other sources observed in the framework of IVS programs; - sources from the NASA Goddard VLBI group catalog5 ; - sources from the RFC catalog,6 which is the most complete astrometric catalog of radio sources, is updated each quarter, and contributed more than half the OCARS objects; the latest version of OCARS used the RFC-2016a catalog based on observations obtained in 1980-2015 as part of IVS and other radio astrometric programs [19-31]; - sources from the literature. Optical Characteristics of Astrometric Radio Sources (OCARS) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Last revised: 27-NOV-2016 Latest update: - removed 30+ RFC sources not identified in NED and optics - removed rather long detailed statistics table, which seems to be not interested for most of users; it is always available on request - a few additions and amendments E-mail alerts about updates are available on request. URL of this file is http://www.gao.spb.ru/english/as/ac_vlbi/ocars.txt Supplement files: Optical and IR magnitudes: http://www.gao.spb.ru/english/as/acvlbi/ocarsm.txt Cross-identification table: http://www.gao.spb.ru/english/as/acvlbi/ocarsn.txt OCARS catalog in CSV format: http://www.gao.spb.ru/english/as/ac_vlbi/ocars.csv Please send comments and requests to Zinovy Malkin, malkin(at)gao.spb.ru ---------------------------------------------------------------------------- The Second Version of the OCARS Catalog of Optical Characteristics of Astrometric Radio Sources. Astronomy Reports, 2016, Vol. 60, No. 11, pp. 996-1005. DOI: 10.1134/S1063772916110032 If you use OCARS catalog in your work, please cite this publication. ---------------------------------------------------------------------- Brief OCARS statistics (detailed statistics is available on request) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Total number of sources 11375 +30...+90 3320 ( 29.2%) -30...+30 6233 ( 54.8%) -90...-30 1822 ( 16.0%) Number of sources with known type 6284 ( 55.2%) AGN 4704 ( 74.9%) quasars 3027 ( 64.3%) BL Lac 992 ( 21.1%) Seyfert 384 ( 8.2%) blazars 89 ( 1.9%) radio galaxies 1580 ( 25.1%) Number of sources with redshift info 5845 ( 51.4%) +30...+90 1803 ( 30.8%) -30...+30 3329 ( 57.0%) -90...-30 713 ( 12.2%) unreliable 868 ( 14.9%) Number of sources with known magnitude 8133 ( 71.5%) +30...+90 2380 ( 29.3%) -30...+30 4481 ( 55.1%) -90...-30 1272 ( 15.6%) Number of sources with both z and magnitude info 5803 ( 51.0%) (3 data files).

The hourly updated US High-Resolution Rapid Refresh (HRRR) storm-scale forecast model

NASA Astrophysics Data System (ADS)

Alexander, Curtis; Dowell, David; Benjamin, Stan; Weygandt, Stephen; Olson, Joseph; Kenyon, Jaymes; Grell, Georg; Smirnova, Tanya; Ladwig, Terra; Brown, John; James, Eric; Hu, Ming

2016-04-01

The 3-km convective-allowing High-Resolution Rapid Refresh (HRRR) is a US NOAA hourly updating weather forecast model that use a specially configured version of the Advanced Research WRF (ARW) model and assimilate many novel and most conventional observation types on an hourly basis using Gridpoint Statistical Interpolation (GSI). Included in this assimilation is a procedure for initializing ongoing precipitation systems from observed radar reflectivity data (and proxy reflectivity from lightning and satellite data), a cloud analysis to initialize stable layer clouds from METAR and satellite observations, and special techniques to enhance retention of surface observation information. The HRRR is run hourly out to 15 forecast hours over a domain covering the entire conterminous United States using initial and boundary conditions from the hourly-cycled 13km Rapid Refresh (RAP, using similar physics and data assimilation) covering North America and a significant part of the Northern Hemisphere. The HRRR is continually developed and refined at NOAA's Earth System Research Laboratory, and an initial version was implemented into the operational NOAA/NCEP production suite in September 2014. Ongoing experimental RAP and HRRR model development throughout 2014 and 2015 has culminated in a set of data assimilation and model enhancements that will be incorporated into the first simultaneous upgrade of both the operational RAP and HRRR that is scheduled for spring 2016 at NCEP. This presentation will discuss the operational RAP and HRRR changes contained in this upgrade. The RAP domain is being expanded to encompass the NAM domain and the forecast lengths of both the RAP and HRRR are being extended. RAP and HRRR assimilation enhancements have focused on (1) extending surface data assimilation to include mesonet observations and improved use of all surface observations through better background estimates of 2-m temperature and dewpoint including projection of 2-m temperature observations through the model boundary layer and (2) extending the use of radar observations to include both radial velocity and 3-D retrieval of rain hydrometeors from observed radar reflectivities in the warm-season. The RAP hybrid EnKF 3D-variational data assimilation will increase weighting of GFS ensemble-based background error covariance estimation and introduce this hybrid data assimilation configuration in the HRRR. Enhancement of RAP and HRRR model physics include improved land surface and boundary layer prediction using the updated Mellor-Yamada-Nakanishi-Niino (MYNN) parameterization scheme, Grell-Freitas-Olson (GFO) shallow and deep convective parameterization, aerosol-aware Thompson microphysics and upgraded Rapid Update Cycle (RUC) land-surface model. The presentation will highlight improvements in the RAP and HRRR model physics to reduce certain systematic forecast biases including a warm and dry daytime bias over the central and eastern CONUS during the warm season along with improved convective forecasts in more weakly-forced diurnally-driven events. Examples of RAP and HRRR forecast improvements will be demonstrated through both retrospective and real-time verification statistics and case-study examples.

Representing Plant Hydraulics in a Global Model: Updates to the Community Land Model

NASA Astrophysics Data System (ADS)

Kennedy, D.; Swenson, S. C.; Oleson, K. W.; Lawrence, D. M.; Fisher, R.; Gentine, P.

2017-12-01

In previous versions, the Community Land Model has used soil moisture to stand in for plant water status, with transpiration and photosynthesis driven directly by soil water potential. This eschews significant literature demonstrating the importance of plant hydraulic traits in the dynamics of water flow through the soil-plant-atmosphere continuum and in the regulation of stomatal aperture. In this study we install a simplified hydraulic framework to represent vegetation water potential and to regulate root water uptake and turbulent fluxes. Plant hydraulics allow for a more explicit representation of plant water status, which improves the physical basis for many processes represented in CLM. This includes root water uptake and the attenuation of photosynthesis and transpiration with drought. Model description is accompanied by results from a point simulation based at the Caxiuanã flux tower site in Eastern Amazonia, covering a throughfall exclusion experiment from 2001-2003. Including plant hydraulics improves the response to drought forcing compared to previous versions of CLM. Parameter sensitivity is examined at the same site and presented in the context of estimating hydraulic parameters in a global model.

ShakeMap Atlas 2.0: an improved suite of recent historical earthquake ShakeMaps for global hazard analyses and loss model calibration

USGS Publications Warehouse

Garcia, D.; Mah, R.T.; Johnson, K.L.; Hearne, M.G.; Marano, K.D.; Lin, K.-W.; Wald, D.J.

2012-01-01

We introduce the second version of the U.S. Geological Survey ShakeMap Atlas, which is an openly-available compilation of nearly 8,000 ShakeMaps of the most significant global earthquakes between 1973 and 2011. This revision of the Atlas includes: (1) a new version of the ShakeMap software that improves data usage and uncertainty estimations; (2) an updated earthquake source catalogue that includes regional locations and finite fault models; (3) a refined strategy to select prediction and conversion equations based on a new seismotectonic regionalization scheme; and (4) vastly more macroseismic intensity and ground-motion data from regional agencies All these changes make the new Atlas a self-consistent, calibrated ShakeMap catalogue that constitutes an invaluable resource for investigating near-source strong ground-motion, as well as for seismic hazard, scenario, risk, and loss-model development. To this end, the Atlas will provide a hazard base layer for PAGER loss calibration and for the Earthquake Consequences Database within the Global Earthquake Model initiative.

Defining Geodetic Reference Frame using Matlab®: PlatEMotion 2.0

NASA Astrophysics Data System (ADS)

Cannavò, Flavio; Palano, Mimmo

2016-03-01

We describe the main features of the developed software tool, namely PlatE-Motion 2.0 (PEM2), which allows inferring the Euler pole parameters by inverting the observed velocities at a set of sites located on a rigid block (inverse problem). PEM2 allows also calculating the expected velocity value for any point located on the Earth providing an Euler pole (direct problem). PEM2 is the updated version of a previous software tool initially developed for easy-to-use file exchange with the GAMIT/GLOBK software package. The software tool is developed in Matlab® framework and, as the previous version, includes a set of MATLAB functions (m-files), GUIs (fig-files), map data files (mat-files) and user's manual as well as some example input files. New changes in PEM2 include (1) some bugs fixed, (2) improvements in the code, (3) improvements in statistical analysis, (4) new input/output file formats. In addition, PEM2 can be now run under the majority of operating systems. The tool is open source and freely available for the scientific community.

Sentry: An Automated Close Approach Monitoring System for Near-Earth Objects

NASA Astrophysics Data System (ADS)

Chamberlin, A. B.; Chesley, S. R.; Chodas, P. W.; Giorgini, J. D.; Keesey, M. S.; Wimberly, R. N.; Yeomans, D. K.

2001-11-01

In response to international concern about potential asteroid impacts on Earth, NASA's Near-Earth Object (NEO) Program Office has implemented a new system called ``Sentry'' to automatically update the orbits of all NEOs on a daily basis and compute Earth close approaches up to 100 years into the future. Results are published on our web site (http://neo.jpl.nasa.gov/) and updated orbits and ephemerides made available via the JPL Horizons ephemeris service (http://ssd.jpl.nasa.gov/horizons.html). Sentry collects new and revised astrometric observations from the Minor Planet Center (MPC) via their electronic circulars (MPECs) in near real time as well as radar and optical astrometry sent directly from observers. NEO discoveries and identifications are detected in MPECs and processed appropriately. In addition to these daily updates, Sentry synchronizes with each monthly batch of MPC astrometry and automatically updates all NEO observation files. Daily and monthly processing of NEO astrometry is managed using a queuing system which allows for manual intervention of selected NEOs without interfering with the automatic system. At the heart of Sentry is a fully automatic orbit determination program which handles outlier rejection and ensures convergence in the new solution. Updated orbital elements and their covariances are published via Horizons and our NEO web site, typically within 24 hours. A new version of Horizons, in development, will allow computation of ephemeris uncertainties using covariance data. The positions of NEOs with updated orbits are numerically integrated up to 100 years into the future and each close approach to any perturbing body in our dynamic model (all planets, Moon, Ceres, Pallas, Vesta) is recorded. Significant approaches are flagged for extended analysis including Monte Carlo studies. Results, such as minimum encounter distances and future Earth impact probabilities, are published on our NEO web site.

UTM TCL 2.0 Software Version Description (SVD) Document

NASA Technical Reports Server (NTRS)

Mcguirk, Patrick

2017-01-01

This is the Unmanned Aircraft Systems (UAS) Traffic Management (UTM) Technical Capability Level(TCL) 2.0 Software Version Description (SVD) document. This UTM TCL 2.0 SVD describes the following four topics: 1. Software Release Contents: A listing of the files comprising this release 2. Installation Instructions: How to install the release and get it running 3. Changes Since Previous Release: General updates since the previous UTM release 4. Known Issues: Known issues and limitations in this release

Selected Vegetables/Sun's Soup (PDQ®)—Patient Version

Cancer.gov

Expert-reviewed information summary about the use of selected vegetables/Sun's soup as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

Cartilage (Bovine and Shark) (PDQ®)—Patient Version

Cancer.gov

Expert-reviewed information summary about the use of bovine and shark cartilage as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

Essiac/Flor Essence (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about the use of Essiac/Flor Essence as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

2005 v4.3 Technical Support Document

EPA Pesticide Factsheets

Emissions Modeling for the Final Mercury and Air Toxics Standards Technical Support Document describes how updated 2005 NEI, version 2 emissions were processed for air quality modeling in support of the final Mercury and Air Toxics Standards (MATS).

The Theory of Rhetorical Criticism: A Bibliography.

ERIC Educational Resources Information Center

Benoit, William L.; Moeder, Michael D.

An updated version of a bibliography which appeared in a 1982 edition of "Rhetoric Society Quarterly," this 132-item bibliography is divided into books and articles and book chapters. The selections date from 1933 through 1989. (NKA)

Cancell/Cantron/Protocel (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about the use of Cancell/Cantron/Protocel as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

Improved version of the PHOBOS Glauber Monte Carlo

DOE PAGES

Loizides, C.; Nagle, J.; Steinberg, P.

2015-09-01

“Glauber” models are used to calculate geometric quantities in the initial state of heavy ion collisions, such as impact parameter, number of participating nucleons and initial eccentricity. Experimental heavy-ion collaborations, in particular at RHIC and LHC, use Glauber Model calculations for various geometric observables for determination of the collision centrality. In this document, we describe the assumptions inherent to the approach, and provide an updated implementation (v2) of the Monte Carlo based Glauber Model calculation, which originally was used by the PHOBOS collaboration. The main improvement w.r.t. the earlier version (v1) (Alver et al. 2008) is the inclusion of Tritium,more » Helium-3, and Uranium, as well as the treatment of deformed nuclei and Glauber–Gribov fluctuations of the proton in p +A collisions. A users’ guide (updated to reflect changes in v2) is provided for running various calculations.« less

Molcas 8: New capabilities for multiconfigurational quantum chemical calculations across the periodic table.

PubMed

Aquilante, Francesco; Autschbach, Jochen; Carlson, Rebecca K; Chibotaru, Liviu F; Delcey, Mickaël G; De Vico, Luca; Fdez Galván, Ignacio; Ferré, Nicolas; Frutos, Luis Manuel; Gagliardi, Laura; Garavelli, Marco; Giussani, Angelo; Hoyer, Chad E; Li Manni, Giovanni; Lischka, Hans; Ma, Dongxia; Malmqvist, Per Åke; Müller, Thomas; Nenov, Artur; Olivucci, Massimo; Pedersen, Thomas Bondo; Peng, Daoling; Plasser, Felix; Pritchard, Ben; Reiher, Markus; Rivalta, Ivan; Schapiro, Igor; Segarra-Martí, Javier; Stenrup, Michael; Truhlar, Donald G; Ungur, Liviu; Valentini, Alessio; Vancoillie, Steven; Veryazov, Valera; Vysotskiy, Victor P; Weingart, Oliver; Zapata, Felipe; Lindh, Roland

2016-02-15

In this report, we summarize and describe the recent unique updates and additions to the Molcas quantum chemistry program suite as contained in release version 8. These updates include natural and spin orbitals for studies of magnetic properties, local and linear scaling methods for the Douglas-Kroll-Hess transformation, the generalized active space concept in MCSCF methods, a combination of multiconfigurational wave functions with density functional theory in the MC-PDFT method, additional methods for computation of magnetic properties, methods for diabatization, analytical gradients of state average complete active space SCF in association with density fitting, methods for constrained fragment optimization, large-scale parallel multireference configuration interaction including analytic gradients via the interface to the Columbus package, and approximations of the CASPT2 method to be used for computations of large systems. In addition, the report includes the description of a computational machinery for nonlinear optical spectroscopy through an interface to the QM/MM package Cobramm. Further, a module to run molecular dynamics simulations is added, two surface hopping algorithms are included to enable nonadiabatic calculations, and the DQ method for diabatization is added. Finally, we report on the subject of improvements with respects to alternative file options and parallelization. © 2015 Wiley Periodicals, Inc.

SecPop Version 4: Sector Population Land Fraction and Economic Estimation Program: Users? Guide Model Manual and Verification Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weber, Scott; Bixler, Nathan E.; McFadden, Katherine Letizia

In 1973 the U.S. Environmental Protection Agency (EPA) developed SecPop to calculate population estimates to support a study on air quality. The Nuclear Regulatory Commission (NRC) adopted this program to support siting reviews for nuclear power plant construction and license applications. Currently SecPop is used to prepare site data input files for offsite consequence calculations with the MELCOR Accident Consequence Code System (MACCS). SecPop enables the use of site-specific population, land use, and economic data for a polar grid defined by the user. Updated versions of SecPop have been released to use U.S. decennial census population data. SECPOP90 was releasedmore » in 1997 to use 1990 population and economic data. SECPOP2000 was released in 2003 to use 2000 population data and 1997 economic data. This report describes the current code version, SecPop version 4.3, which uses 2010 population data and both 2007 and 2012 economic data. It is also compatible with 2000 census and 2002 economic data. At the time of this writing, the current version of SecPop is 4.3.0, and that version is described herein. This report contains guidance for the installation and use of the code as well as a description of the theory, models, and algorithms involved. This report contains appendices which describe the development of the 2010 census file, 2007 county file, and 2012 county file. Finally, an appendix is included that describes the validation assessments performed.« less

CyanoBase: the cyanobacteria genome database update 2010

PubMed Central

Nakao, Mitsuteru; Okamoto, Shinobu; Kohara, Mitsuyo; Fujishiro, Tsunakazu; Fujisawa, Takatomo; Sato, Shusei; Tabata, Satoshi; Kaneko, Takakazu; Nakamura, Yasukazu

2010-01-01

CyanoBase (http://genome.kazusa.or.jp/cyanobase) is the genome database for cyanobacteria, which are model organisms for photosynthesis. The database houses cyanobacteria species information, complete genome sequences, genome-scale experiment data, gene information, gene annotations and mutant information. In this version, we updated these datasets and improved the navigation and the visual display of the data views. In addition, a web service API now enables users to retrieve the data in various formats with other tools, seamlessly. PMID:19880388

Highlights of the 2017 European AIDS Clinical Society (EACS) Guidelines for the treatment of adult HIV-positive persons version 9.0.

PubMed

Ryom, L; Boesecke, C; Bracchi, M; Ambrosioni, J; Pozniak, A; Arribas, J; Behrens, G; Mallon, Pgm; Puoti, M; Rauch, A; Miro, J M; Kirk, O; Marzolini, C; Lundgren, J D; Battegay, M

2018-05-01

The European AIDS Clinical Society (EACS) Guidelines have since 2005 provided multidisciplinary recommendations for the care of HIV-positive persons in geographically diverse areas. Major revisions have been made in all sections of the 2017 Guidelines: antiretroviral treatment (ART), comorbidities, coinfections and opportunistic diseases. Newly added are also a summary of the main changes made, and direct video links to the EACS online course on HIV Management. Recommendations on the clinical situations in which tenofovir alafenamide may be considered over tenofovir disoproxil fumarate are provided, and recommendations on which antiretrovirals can be used safely during pregnancy have been revised. Renal and bone toxicity and hepatitis C virus (HCV) treatment have been added as potential reasons for ART switches in fully virologically suppressed individuals, and dolutegravir/rilpivirine has been included as a treatment option. In contrast, dolutegravir monotherapy is not recommended. New recommendations on non-alcoholic fatty liver disease, chronic lung disease, solid organ transplantation, and prescribing in elderly are included, and human papilloma virus (HPV) vaccination recommendations have been expanded. All drug-drug interaction tables have been updated and new tables are included. Treatment options for direct-acting antivirals (DAAs) have been updated and include the latest combinations of sofosbuvir/velpatasvir/voxilaprevir and glecaprevir/pibrentasvir. Recommendations on management of DAA failure and acute HCV infection have been expanded. For treatment of tuberculosis (TB), it is underlined that intermittent treatment is contraindicated, and for resistant TB new data suggest that using a three-drug combination may be as effective as a five-drug regimen, and may reduce treatment duration from 18-24 to 6-10 months. Version 9.0 of the EACS Guidelines provides a holistic approach to HIV care and is translated into the six most commonly spoken languages. © 2018 The Authors. HIV Medicine Published by John Wiley & Sons Ltd on behalf of British HIV Association.

VizieR Online Data Catalog: SKY2000 Master Catalog, Version 5 (Myers+ 2006)

NASA Astrophysics Data System (ADS)

Myers, J. R.; Sande, C. B.; Miller, A. C.; Warren, W. H., Jr.; Tracewell, D. A.

2015-02-01

The SKYMAP Star Catalog System consists of a Master Catalog stellar database and a collection of utility software designed to create and maintain the database and to generate derivative mission star catalogs (run catalogs). It contains an extensive compilation of information on almost 300000 stars brighter than 8.0mag. The original SKYMAP Master Catalog was generated in the early 1970's. Incremental updates and corrections were made over the following years but the first complete revision of the source data occurred with Version 4.0. This revision also produced a unique, consolidated source of astrometric information which can be used by the astronomical community. The derived quantities were removed and wideband and photometric data in the R (red) and I (infrared) systems were added. Version 4 of the SKY2000 Master Catalog was completed in April 2002; it marks the global replacement of the variability identifier and variability data fields. More details can be found in the description file sky2kv4.pdf. The SKY2000 Version 5 Revision 4 Master Catalog differs from Revision 3 in that MK and HD spectral types have been added from the Catalogue of Stellar Spectral Classifications (B. A. Skiff of Lowell Observatory, 2005), which has been assigned source code 50 in this process. 9622 entries now have MK types from this source, while 3976 entries have HD types from this source. SKY2000 V5 R4 also differs globally from preceding MC versions in that the Galactic coordinate computations performed by UPDATE have been increased in accuracy, so that differences from the same quantities from other sources are now typically in the last decimal places carried in the MC. This version supersedes the previous versions 1(V/95), 2(V/102), 3(V/105) and 4(V/109). (6 data files).

OLS Client and OLS Dialog: Open Source Tools to Annotate Public Omics Datasets.

PubMed

Perez-Riverol, Yasset; Ternent, Tobias; Koch, Maximilian; Barsnes, Harald; Vrousgou, Olga; Jupp, Simon; Vizcaíno, Juan Antonio

2017-10-01

The availability of user-friendly software to annotate biological datasets and experimental details is becoming essential in data management practices, both in local storage systems and in public databases. The Ontology Lookup Service (OLS, http://www.ebi.ac.uk/ols) is a popular centralized service to query, browse and navigate biomedical ontologies and controlled vocabularies. Recently, the OLS framework has been completely redeveloped (version 3.0), including enhancements in the data model, like the added support for Web Ontology Language based ontologies, among many other improvements. However, the new OLS is not backwards compatible and new software tools are needed to enable access to this widely used framework now that the previous version is no longer available. We here present the OLS Client as a free, open-source Java library to retrieve information from the new version of the OLS. It enables rapid tool creation by providing a robust, pluggable programming interface and common data model to programmatically access the OLS. The library has already been integrated and is routinely used by several bioinformatics resources and related data annotation tools. Secondly, we also introduce an updated version of the OLS Dialog (version 2.0), a Java graphical user interface that can be easily plugged into Java desktop applications to access the OLS. The software and related documentation are freely available at https://github.com/PRIDE-Utilities/ols-client and https://github.com/PRIDE-Toolsuite/ols-dialog. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Metallic Fuels Handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Janney, Dawn E.; Papesch, Cynthia A.; Burkes, Douglas E.

This is not a typical External Report--It is a Handbook. No Abstract is involved. This includes both Parts 1 and 2. The Metallic Fuels Handbook summarizes currently available information about phases and phase diagrams, heat capacity, thermal expansion, and thermal conductivity of elements and alloys in the U-Pu-Zr-Np-Am-La-Ce-Pr-Nd system. Although many sections are reviews and updates of material in previous versions of the Handbook [1, 2], this revision is the first to include alloys with four or more elements. In addition to presenting information about materials properties, the handbook attempts to provide information about how well each property is knownmore » and how much variation exists between measurements. Although it includes some results from models, its primary focus is experimental data.« less

Selected Vegetables/Sun's Soup (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about the use of selected vegetables/Sun's soup as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

Galactic cosmic radiation exposure of pregnant aircrew members II

DOT National Transportation Integrated Search

2000-10-01

This report is an updated version of a previously published Technical Note in the journal Aviation, Space, and Environmental Medicine. The main change is that improved computer programs were used to estimate galactic cosmic radiation. The calculation...

Response Surface Model (RSM)-based Benefit Per Ton Estimates

EPA Pesticide Factsheets

The tables below are updated versions of the tables appearing in The influence of location, source, and emission type in estimates of the human health benefits of reducing a ton of air pollution (Fann, Fulcher and Hubbell 2009).

MISR Data Product Specifications

Atmospheric Science Data Center

2016-11-25

... and usage of metadata. Improvements to MISR algorithmic software occasionally result in changes to file formats. While these changes ...  (DPS).   DPS Revision:   Rev. S Software Version:  5.0.9 Date:  September 20, 2010, updated April ...

Cartilage (Bovine and Shark) (PDQ®)—Health Professional Version

Cancer.gov

Expert-reviewed information summary about the use of bovine and shark cartilage as a treatment for people with cancer. Note: The information in this summary is no longer being updated and is provided for reference purposes only.

2015 U.S. Lighting Market Characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The latest version of the U.S. Lighting Market Characterization estimates the installed stock, energy use, and lumen production of all general-illumination lighting products operating in the U.S. in 2015. Latest update in an ongoing series of reports.

The Radio Sky and the Echo of Creation.

ERIC Educational Resources Information Center

Ferris, Timothy

1984-01-01

Presents a selection from a revised and updated version of "The Red Limit" by Timothy Ferris. The book is a completely nontechnical introduction to 20th century cosmology, the study of the large-scale properties of the universe. (JN)

What Is Vocal Cord Dysfunction (VCD)?

MedlinePlus

... from asthma, VCD, or both at the same time. Am J Respir Crit Care Med Vol. 180, P5-P6, 2009. Online Version Updated September 2013 ATS Patient Education Series © 2009 American Thoracic Society www.thoracic.org ATS ...

Installing the Unix Starlink Software

NASA Astrophysics Data System (ADS)

Bly, M. J.

This note is the release note and installation instructions for the DEC Alpha AXP / Digital UNIX, Sun Sparc / Solaris v2.x, and Sun Sparc / SunOS 4.1.x versions of the Starlink Software Collection (USSC). You will be supplied with pre-built (and installed) versions on tape and will just need to copy the tape to disk to have a working version. The tapes (where appropriate) will contain in addition, copies of the NAG and MEMSYS libraries, and Tcl, Tk, Expect, Mosaic, TeX, Pine, Perl, Jed, Ispell, Ghostscript, LaXeX2html and Ftnchek for the relevant system. The Sun Sparc SunOS 4.1.x version of the USSC was frozen at USSC111 and no further updates are available. The instructions for installing the main section of the USSC may continue to be used for installing Sun Sparc SunOS 4.1.x version.

The Snow Data System at NASA JPL

NASA Astrophysics Data System (ADS)

Laidlaw, R.; Painter, T. H.; Mattmann, C. A.; Ramirez, P.; Brodzik, M. J.; Rittger, K.; Bormann, K. J.; Burgess, A. B.; Zimdars, P.; McGibbney, L. J.; Goodale, C. E.; Joyce, M.

2015-12-01

The Snow Data System at NASA JPL includes a data processing pipeline built with open source software, Apache 'Object Oriented Data Technology' (OODT). It produces a variety of data products using inputs from satellites such as MODIS, VIIRS and Landsat. Processing is carried out in parallel across a high-powered computing cluster. Algorithms such as 'Snow Covered Area and Grain-size' (SCAG) and 'Dust Radiative Forcing in Snow' (DRFS) are applied to satellite inputs to produce output images that are used by many scientists and institutions around the world. This poster will describe the Snow Data System, its outputs and their uses and applications, along with recent advancements to the system and plans for the future. Advancements for 2015 include automated daily processing of historic MODIS data for SCAG (MODSCAG) and DRFS (MODDRFS), automation of SCAG processing for VIIRS satellite inputs (VIIRSCAG) and an updated version of SCAG for Landsat Thematic Mapper inputs (TMSCAG) that takes advantage of Graphics Processing Units (GPUs) for faster processing speeds. The pipeline has been upgraded to use the latest version of OODT and its workflows have been streamlined to enable computer operators to process data on demand. Additional products have been added, such as rolling 8-day composites of MODSCAG data, a new version of the MODSCAG 'annual minimum ice and snow extent' (MODICE) product, and recoded MODSCAG data for the 'Satellite Snow Product Intercomparison and Evaluation Experiment' (SnowPEx) project.

Gene Ontology annotation of the rice blast fungus, Magnaporthe oryzae

PubMed Central

Meng, Shaowu; Brown, Douglas E; Ebbole, Daniel J; Torto-Alalibo, Trudy; Oh, Yeon Yee; Deng, Jixin; Mitchell, Thomas K; Dean, Ralph A

2009-01-01

Background Magnaporthe oryzae, the causal agent of blast disease of rice, is the most destructive disease of rice worldwide. The genome of this fungal pathogen has been sequenced and an automated annotation has recently been updated to Version 6 . However, a comprehensive manual curation remains to be performed. Gene Ontology (GO) annotation is a valuable means of assigning functional information using standardized vocabulary. We report an overview of the GO annotation for Version 5 of M. oryzae genome assembly. Methods A similarity-based (i.e., computational) GO annotation with manual review was conducted, which was then integrated with a literature-based GO annotation with computational assistance. For similarity-based GO annotation a stringent reciprocal best hits method was used to identify similarity between predicted proteins of M. oryzae and GO proteins from multiple organisms with published associations to GO terms. Significant alignment pairs were manually reviewed. Functional assignments were further cross-validated with manually reviewed data, conserved domains, or data determined by wet lab experiments. Additionally, biological appropriateness of the functional assignments was manually checked. Results In total, 6,286 proteins received GO term assignment via the homology-based annotation, including 2,870 hypothetical proteins. Literature-based experimental evidence, such as microarray, MPSS, T-DNA insertion mutation, or gene knockout mutation, resulted in 2,810 proteins being annotated with GO terms. Of these, 1,673 proteins were annotated with new terms developed for Plant-Associated Microbe Gene Ontology (PAMGO). In addition, 67 experiment-determined secreted proteins were annotated with PAMGO terms. Integration of the two data sets resulted in 7,412 proteins (57%) being annotated with 1,957 distinct and specific GO terms. Unannotated proteins were assigned to the 3 root terms. The Version 5 GO annotation is publically queryable via the GO site . Additionally, the genome of M. oryzae is constantly being refined and updated as new information is incorporated. For the latest GO annotation of Version 6 genome, please visit our website . The preliminary GO annotation of Version 6 genome is placed at a local MySql database that is publically queryable via a user-friendly interface Adhoc Query System. Conclusion Our analysis provides comprehensive and robust GO annotations of the M. oryzae genome assemblies that will be solid foundations for further functional interrogation of M. oryzae. PMID:19278556

Signaling through the PI 3-K, Akt and SGK Pathway in Breast Cancer Progression

DTIC Science & Technology

2013-12-01

Cancer Cell Migration The Adherens Junction Protein Afadin is an Akt substrate that Updated version 10.1158/1541-7786. MCR -13-0398doi: Access...the most recent version of this article at: Material Supplementary http://mcr.aacrjournals.org/content/suppl/2013/11/22/1541-7786. MCR -13-0398.DC1...accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on November 22, 2013; DOI: 10.1158/1541-7786. MCR -13-0398

Fine-Root Ecology Database (FRED): A Global Collection of Root Trait Data with Coincident Site, Vegetation, Edaphic, and Climatic Data, Version 2.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Iversen, C.M.; Powell, A.S.; McCormack, M.L.

The second version of the Fine-Root Ecology Database is available for download! Download the full FRED 2.0 data set, user guidance document, map, and list of data sources here. Prior to downloading the data, please read and follow the Data Use Guidelines, and it's worth checking out some tips for using FRED before you begin your analyses. Also, see here for an updating list of corrections to FRED 2.0.

Refinements to the Graves and Pitarka (2010) Broadband Ground-Motion Simulation Method

DOE PAGES

Graves, Robert; Pitarka, Arben

2014-12-17

This brief article describes refinements to the Graves and Pitarka (2010) broadband ground-motion simulation methodology (GP2010 hereafter) that have been implemented in version 14.3 of the Southern California Earthquake Center (SCEC) Broadband Platform (BBP). The updated version of our method on the current SCEC BBP is referred to as GP14.3. Here, our simulation technique is a hybrid approach that combines low- and high-frequency motions computed with different methods into a single broadband response.

Improvements to NASA's Debris Assessment Software

NASA Technical Reports Server (NTRS)

Opiela, J.; Johnson, Nicholas L.

2007-01-01

NASA's Debris Assessment Software (DAS) has been substantially revised and expanded. DAS is designed to assist NASA programs in performing orbital debris assessments, as described in NASA s Guidelines and Assessment Procedures for Limiting Orbital Debris. The extensive upgrade of DAS was undertaken to reflect changes in the debris mitigation guidelines, to incorporate recommendations from DAS users, and to take advantage of recent software capabilities for greater user utility. DAS 2.0 includes an updated environment model and enhanced orbital propagators and reentry-survivability models. The ORDEM96 debris environment model has been replaced by ORDEM2000 in DAS 2.0, which is also designed to accept anticipated revisions to the environment definition. Numerous upgrades have also been applied to the assessment of human casualty potential due to reentering debris. Routines derived from the Object Reentry Survival Analysis Tool, Version 6 (ORSAT 6), determine which objects are assessed to survive reentry, and the resulting risk of human casualty is calculated directly based upon the orbital inclination and a future world population database. When evaluating reentry risks, the user may enter up to 200 unique hardware components for each launched object, in up to four nested levels. This last feature allows the software to more accurately model components that are exposed below the initial breakup altitude. The new DAS 2.0 provides an updated set of tools for users to assess their mission s compliance with the NASA Safety Standard and does so with a clear and easy-to-understand interface. The new native Microsoft Windows graphical user interface (GUI) is a vast improvement over the previous DOS-based interface. In the new version, functions are more-clearly laid out, and the GUI includes the standard Windows-style Help functions. The underlying routines within the DAS code are also improved.

Representation of the Community Earth System Model (CESM1) CAM4-chem within the Chemistry-Climate Model Initiative (CCMI)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tilmes, Simone; Lamarque, Jean -Francois; Emmons, Louisa K.

The Community Earth System Model (CESM1) CAM4-chem has been used to perform the Chemistry Climate Model Initiative (CCMI) reference and sensitivity simulations. In this model, the Community Atmospheric Model version 4 (CAM4) is fully coupled to tropospheric and stratospheric chemistry. Details and specifics of each configuration, including new developments and improvements are described. CESM1 CAM4-chem is a low-top model that reaches up to approximately 40 km and uses a horizontal resolution of 1.9° latitude and 2.5° longitude. For the specified dynamics experiments, the model is nudged to Modern-Era Retrospective Analysis for Research and Applications (MERRA) reanalysis. We summarize the performance ofmore » the three reference simulations suggested by CCMI, with a focus on the last 15 years of the simulation when most observations are available. Comparisons with selected data sets are employed to demonstrate the general performance of the model. We highlight new data sets that are suited for multi-model evaluation studies. Most important improvements of the model are the treatment of stratospheric aerosols and the corresponding adjustments for radiation and optics, the updated chemistry scheme including improved polar chemistry and stratospheric dynamics and improved dry deposition rates. These updates lead to a very good representation of tropospheric ozone within 20 % of values from available observations for most regions. In particular, the trend and magnitude of surface ozone is much improved compared to earlier versions of the model. Furthermore, stratospheric column ozone of the Southern Hemisphere in winter and spring is reasonably well represented. In conclusion, all experiments still underestimate CO most significantly in Northern Hemisphere spring and show a significant underestimation of hydrocarbons based on surface observations.« less

Representation of the Community Earth System Model (CESM1) CAM4-chem within the Chemistry-Climate Model Initiative (CCMI)

DOE PAGES

Tilmes, Simone; Lamarque, Jean -Francois; Emmons, Louisa K.; ...

2016-05-20

The Community Earth System Model (CESM1) CAM4-chem has been used to perform the Chemistry Climate Model Initiative (CCMI) reference and sensitivity simulations. In this model, the Community Atmospheric Model version 4 (CAM4) is fully coupled to tropospheric and stratospheric chemistry. Details and specifics of each configuration, including new developments and improvements are described. CESM1 CAM4-chem is a low-top model that reaches up to approximately 40 km and uses a horizontal resolution of 1.9° latitude and 2.5° longitude. For the specified dynamics experiments, the model is nudged to Modern-Era Retrospective Analysis for Research and Applications (MERRA) reanalysis. We summarize the performance ofmore » the three reference simulations suggested by CCMI, with a focus on the last 15 years of the simulation when most observations are available. Comparisons with selected data sets are employed to demonstrate the general performance of the model. We highlight new data sets that are suited for multi-model evaluation studies. Most important improvements of the model are the treatment of stratospheric aerosols and the corresponding adjustments for radiation and optics, the updated chemistry scheme including improved polar chemistry and stratospheric dynamics and improved dry deposition rates. These updates lead to a very good representation of tropospheric ozone within 20 % of values from available observations for most regions. In particular, the trend and magnitude of surface ozone is much improved compared to earlier versions of the model. Furthermore, stratospheric column ozone of the Southern Hemisphere in winter and spring is reasonably well represented. In conclusion, all experiments still underestimate CO most significantly in Northern Hemisphere spring and show a significant underestimation of hydrocarbons based on surface observations.« less

Portuguese recommendations for the prevention, diagnosis and management of primary osteoporosis - 2018 update.

PubMed

Rodrigues, A M; Canhão, H; Marques, A; Ambrósio, C; Borges, J; Coelho, P; Costa, L; Fernandes, S; Gonçalves, I; Gonçalves, M; Guerra, M; Marques, M L; Pimenta, S; Pinto, P; Sequeira, G; Simões, E; Teixeira, L; Vaz, C; Vieira-Sousa, E; Vieira, R; Alvarenga, F; Araújo, F; Barcelos, A; Barcelos, F; Barros, R; Bernardes, M; Canas da Silva, J; Cordeiro, A; Costa, M; Cunha-Miranda, L; Cruz, M; Duarte, A C; Duarte, C; Faustino, A; Figueiredo, G; Fonseca, J E; Furtado, C; Gomes, J; Lopes, C; Mourão, A F; Oliveira, M; Pimentel-Santos, F M; Ribeiro, A; Sampaio da Nóvoa, T; Santiago, M; Silva, C; Silva-Dinis, A; Sousa, S; Tavares-Costa, J; Terroso, G; Vilar, A; Branco, J C; Tavares, V; Romeu, J C; da Silva, Jap

2018-01-01

Advances in osteoporosis (OP)case definition, treatment options, optimal therapy duration and pharmacoeconomic evidence in the national context motivated the Portuguese Society of Rheumatology (SPR) to update the Portuguese recommendations for the diagnosis and management of osteoporosis published in 2007. SPR bone diseases' working group organized meetings involving 55 participants (rheumatologists, rheumatology fellows and one OP specialist nurse) to debate and develop the document. First, the working group selected 11 pertinent clinical questions for the diagnosis and management of osteoporosis in standard clinical practice. Then, each question was investigated through literature review and draft recommendations were built through consensus. When insufficient evidence was available, recommendations were based on experts' opinion and on good clinical practice. At two national meetings, the recommendations were discussed and updated. A draft of the recommendations full text was submitted to critical review among the working group and suggestions were incorporated. A final version was circulated among all Portuguese rheumatologists before publication and the level of agreement was anonymously assessed using an online survey. The 2018 SPR recommendations provide comprehensive guidance on osteoporosis prevention, diagnosis, fracture risk assessment, pharmacological treatment initiation, therapy options and duration of treatment, based on the best available evidence. They attained desirable agreement among Portuguese rheumatologists. As more evidence becomes available, periodic revisions will be performed. Target audience and patient population: The target audience for these guidelines includes all clinicians. The target patient population includes adult Portuguese people. Intended use: These recommendations provide general guidance for typical cases. They may not be appropriate in all situations - clinicians are encouraged to consider this information together with updated evidence and their best clinical judgment in individual cases.

2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines.

PubMed

Ferraris, Victor A; Brown, Jeremiah R; Despotis, George J; Hammon, John W; Reece, T Brett; Saha, Sibu P; Song, Howard K; Clough, Ellen R; Shore-Lesserson, Linda J; Goodnough, Lawrence T; Mazer, C David; Shander, Aryeh; Stafford-Smith, Mark; Waters, Jonathan; Baker, Robert A; Dickinson, Timothy A; FitzGerald, Daniel J; Likosky, Donald S; Shann, Kenneth G

2011-03-01

Practice guidelines reflect published literature. Because of the ever changing literature base, it is necessary to update and revise guideline recommendations from time to time. The Society of Thoracic Surgeons recommends review and possible update of previously published guidelines at least every three years. This summary is an update of the blood conservation guideline published in 2007. The search methods used in the current version differ compared to the previously published guideline. Literature searches were conducted using standardized MeSH terms from the National Library of Medicine PUBMED database list of search terms. The following terms comprised the standard baseline search terms for all topics and were connected with the logical 'OR' connector--Extracorporeal circulation (MeSH number E04.292), cardiovascular surgical procedures (MeSH number E04.100), and vascular diseases (MeSH number C14.907). Use of these broad search terms allowed specific topics to be added to the search with the logical 'AND' connector. In this 2011 guideline update, areas of major revision include: 1) management of dual anti-platelet therapy before operation, 2) use of drugs that augment red blood cell volume or limit blood loss, 3) use of blood derivatives including fresh frozen plasma, Factor XIII, leukoreduced red blood cells, platelet plasmapheresis, recombinant Factor VII, antithrombin III, and Factor IX concentrates, 4) changes in management of blood salvage, 5) use of minimally invasive procedures to limit perioperative bleeding and blood transfusion, 6) recommendations for blood conservation related to extracorporeal membrane oxygenation and cardiopulmonary perfusion, 7) use of topical hemostatic agents, and 8) new insights into the value of team interventions in blood management. Much has changed since the previously published 2007 STS blood management guidelines and this document contains new and revised recommendations. Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Communication Services and Supports for Individuals With Severe Disabilities: Guidance for Assessment and Intervention.

PubMed

Brady, Nancy C; Bruce, Susan; Goldman, Amy; Erickson, Karen; Mineo, Beth; Ogletree, Bill T; Paul, Diane; Romski, Mary Ann; Sevcik, Rose; Siegel, Ellin; Schoonover, Judith; Snell, Marti; Sylvester, Lorraine; Wilkinson, Krista

2016-03-01

The National Joint Committee for the Communication Needs of People With Severe Disabilities (NJC) reviewed literature regarding practices for people with severe disabilities in order to update guidance provided in documents originally published in 1992. Changes in laws, definitions, and policies that affect communication attainments by persons with severe disabilities are presented, along with guidance regarding assessment and intervention practices. A revised version of the Communication Bill of Rights, a powerful document that describes the communication rights of all individuals, including those with severe disabilities is included in this article. The information contained within this article is intended to be used by professionals, family members, and individuals with severe disabilities to inform and advocate for effective communication services and opportunities.

Wilbur and Orville Wright: A Bibliography Commemorating the One-Hundredth Anniversary of the First Powered Flight, December 17, 1903. Revised

NASA Technical Reports Server (NTRS)

Renstrom, Arthur G. (Compiler); Goldblatt, Roberta W.; Minkus, Carl; Berube, Karen L.; Launius, Roger (Technical Monitor)

2002-01-01

This annotated bibliography of material about Wilbur and Orville Wright and the first powered flight, commemorates the one hundredth anniversary of the event. This publication represents an updated version of the classic, "Wilbur and Orville Wright: A Bibliography Commemorating the Hundredth Anniversary of the Birth of Wilbur Wright, April 16, 1867" which was originally published in 1968. Aspects of the Wright brothers' lives covered include: their published writings, biographical references, airplanes used and flight records, airplane components, patents, court records, Wright companies and schools, the Wright-Smithsonian controversy, monuments and museums, memorials, medals and honors, memorabilia, art, poetry, music, motion pictures and juvenile publications. An index is included.

Simulation of ultra-high energy photon propagation with PRESHOWER 2.0

NASA Astrophysics Data System (ADS)

Homola, P.; Engel, R.; Pysz, A.; Wilczyński, H.

2013-05-01

In this paper we describe a new release of the PRESHOWER program, a tool for Monte Carlo simulation of propagation of ultra-high energy photons in the magnetic field of the Earth. The PRESHOWER program is designed to calculate magnetic pair production and bremsstrahlung and should be used together with other programs to simulate extensive air showers induced by photons. The main new features of the PRESHOWER code include a much faster algorithm applied in the procedures of simulating the processes of gamma conversion and bremsstrahlung, update of the geomagnetic field model, and a minor correction. The new simulation procedure increases the flexibility of the code so that it can also be applied to other magnetic field configurations such as, for example, encountered in the vicinity of the sun or neutron stars. Program summaryProgram title: PRESHOWER 2.0 Catalog identifier: ADWG_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADWG_v2_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 3968 No. of bytes in distributed program, including test data, etc.: 37198 Distribution format: tar.gz Programming language: C, FORTRAN 77. Computer: Intel-Pentium based PC. Operating system: Linux or Unix. RAM:< 100 kB Classification: 1.1. Does the new version supercede the previous version?: Yes Catalog identifier of previous version: ADWG_v1_0 Journal reference of previous version: Comput. Phys. Comm. 173 (2005) 71 Nature of problem: Simulation of a cascade of particles initiated by UHE photon in magnetic field. Solution method: The primary photon is tracked until its conversion into an e+ e- pair. If conversion occurs each individual particle in the resultant preshower is checked for either bremsstrahlung radiation (electrons) or secondary gamma conversion (photons). Reasons for new version: Slow and outdated algorithm in the old version (a significant speed up is possible); Extension of the program to allow simulations also for extraterrestrial magnetic field configurations (e.g. neutron stars) and very long path lengths. Summary of revisions: A veto algorithm was introduced in the gamma conversion and bremsstrahlung tracking procedures. The length of the tracking step is now variable along the track and depends on the probability of the process expected to occur. The new algorithm reduces significantly the number of tracking steps and speeds up the execution of the program. The geomagnetic field model has been updated to IGRF-11, allowing for interpolations up to the year 2015. Numerical Recipes procedures to calculate modified Bessel functions have been replaced with an open source CERN routine DBSKA. One minor bug has been fixed. Restrictions: Gamma conversion into particles other than an electron pair is not considered. Spatial structure of the cascade is neglected. Additional comments: The following routines are supplied in the package, IGRF [1, 2], DBSKA [3], ran2 [4] Running time: 100 preshower events with primary energy 1020 eV require a 2.66 GHz CPU time of about 200 sec.; at the energy of 1021 eV, 600 sec.

Improving the Amazonian Hydrologic Cycle in a Coupled Land-Atmosphere, Single Column Model

NASA Astrophysics Data System (ADS)

Harper, A. B.; Denning, S.; Baker, I.; Prihodko, L.; Branson, M.

2006-12-01

We have coupled a land-surface model, the Simple Biosphere Model (SiB3), to a single column of the Colorado State University General Circulation Model (CSU-GCM) in the Amazon River Basin. This is a preliminary step in the broader goal of improved simulation of Basin-wide hydrology. A previous version of the coupled model (SiB2) showed drought and catastrophic dieback of the Amazon rain forest. SiB3 includes updated soil hydrology and root physiology. Our test area for the coupled single column model is near Santarem, Brazil, where measurements from the km 83 flux tower in the Tapajos National Forest can be used to evaluate model output. The model was run for 2001 using NCEP2 Reanalysis as driver data. Preliminary results show that the updated biosphere model coupled to the GCM produces improved simulations of the seasonal cycle of surface water balance and precipitation. Comparisons of the diurnal and seasonal cycles of surface fluxes are also being made.

Core informatics competencies for clinical and translational scientists: what do our customers and collaborators need to know?

PubMed Central

Valenta, Annette L; Meagher, Emma A; Tachinardi, Umberto

2016-01-01

Since the inception of the Clinical and Translational Science Award (CTSA) program in 2006, leaders in education across CTSA sites have been developing and updating core competencies for Clinical and Translational Science (CTS) trainees. By 2009, 14 competency domains, including biomedical informatics, had been identified and published. Since that time, the evolution of the CTSA program, changes in the practice of CTS, the rapid adoption of electronic health records (EHRs), the growth of biomedical informatics, the explosion of big data, and the realization that some of the competencies had proven to be difficult to apply in practice have made it clear that the competencies should be updated. This paper describes the process undertaken and puts forth a new set of competencies that has been recently endorsed by the Clinical Research Informatics Workgroup of AMIA. In addition to providing context and background for the current version of the competencies, we hope this will serve as a model for revision of competencies over time. PMID:27121608

Update of the androgen receptor gene mutations database.

PubMed

Gottlieb, B; Beitel, L K; Lumbroso, R; Pinsky, L; Trifiro, M

1999-01-01

The current version of the androgen receptor (AR) gene mutations database is described. The total number of reported mutations has risen from 309 to 374 during the past year. We have expanded the database by adding information on AR-interacting proteins; and we have improved the database by identifying those mutation entries that have been updated. Mutations of unknown significance have now been reported in both the 5' and 3' untranslated regions of the AR gene, and in individuals who are somatic mosaics constitutionally. In addition, single nucleotide polymorphisms, including silent mutations, have been discovered in normal individuals and in individuals with male infertility. A mutation hotspot associated with prostatic cancer has been identified in exon 5. The database is available on the internet (http://www.mcgill.ca/androgendb/), from EMBL-European Bioinformatics Institute (ftp.ebi.ac.uk/pub/databases/androgen), or as a Macintosh FilemakerPro or Word file (MC33@musica.mcgill.ca). Copyright 1999 Wiley-Liss, Inc.

ADVISORY ON UPDATED METHODOLOGY FOR ...

EPA Pesticide Factsheets

The National Academy of Sciences (NAS) published the Biological Effects of Ionizing Radiation (BEIR) committee's report (BEIR VII) on risks from ionizing radiation exposures in 2006. The Committee analyzed the most recent epidemiology from the important exposed cohorts and factored in changes resulting from the updated analysis of dosimetry for the Japanese atomic bomb survivors. To the extent practical, the Committee also considered relevant radiobiological data, including that from the Department of Energy's low dose effects research program. Based on the review of this information, the Committee proposed a set of models for estimating risks from low-dose ionizing radiation. ORIA then prepared a white paper revising the Agency's methodology for estimating cancer risks from exposure to ionizing radiation in light of this report and other relevant information. This is the first product to be developed as a result of the BEIR VII report. We requested that the SAB conduct an advisory during the development of this methodology. The second product to be prepared will be a revised version of the document,

The Next-generation Berkeley High Resolution NO2 (BEHR NO2) Retrieval: Design and Preliminary Emissions Constraints

NASA Astrophysics Data System (ADS)

Laughner, J.; Cohen, R. C.

2017-12-01

Recent work has identified a number of assumptions made in NO2 retrievals that lead to biases in the retrieved NO2 column density. These include the treatment of the surface as an isotropic reflector, the absence of lightning NO2 in high resolution a priori profiles, and the use of monthly averaged a priori profiles. We present a new release of the Berkeley High Resolution (BEHR) OMI NO2 retrieval based on the new NASA Standard Product (version 3) that addresses these assumptions by: accounting for surface anisotropy by using a BRDF albedo product, using an updated method of regridding NO2 data, and revised NO2 a priori profiles that better account for lightning NO2 and daily variation in the profile shape. We quantify the effect these changes have on the retrieved NO2 column densities and the resultant impact these updates have on constraints of urban NOx emissions for select cities throughout the United States.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dai, Qiang; Kelly, Jarod C.; Burnham, Andrew

This report serves as an update for the life-cycle analysis (LCA) of aluminum production based on the most recent data representing the state-of-the-art of the industry in North America. The 2013 Aluminum Association (AA) LCA report on the environmental footprint of semifinished aluminum products in North America provides the basis for the update (The Aluminum Association, 2013). The scope of this study covers primary aluminum production, secondary aluminum production, as well as aluminum semi-fabrication processes including hot rolling, cold rolling, extrusion and shape casting. This report focuses on energy consumptions, material inputs and criteria air pollutant emissions for each processmore » from the cradle-to-gate of aluminum, which starts from bauxite extraction, and ends with manufacturing of semi-fabricated aluminum products. The life-cycle inventory (LCI) tables compiled are to be incorporated into the vehicle cycle model of Argonne National Laboratory’s Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET) Model for the release of its 2015 version.« less

Update of the trauma risk adjustment model of the TraumaRegister DGU™: the Revised Injury Severity Classification, version II.

PubMed

Lefering, Rolf; Huber-Wagner, Stefan; Nienaber, Ulrike; Maegele, Marc; Bouillon, Bertil

2014-09-05

The TraumaRegister DGU™ (TR-DGU) has used the Revised Injury Severity Classification (RISC) score for outcome adjustment since 2003. In recent years, however, the observed mortality rate has fallen to about 2% below the prognosis, and it was felt that further prognostic factors, like pupil size and reaction, should be included as well. Finally, an increasing number of cases did not receive a RISC prognosis due to the missing values. Therefore, there was a need for an updated model for risk of death prediction in severely injured patients to be developed and validated using the most recent data. The TR-DGU has been collecting data from severely injured patients since 1993. All injuries are coded according to the Abbreviated Injury Scale (AIS, version 2008). Severely injured patients from Europe (ISS ≥ 4) documented between 2010 and 2011 were selected for developing the new score (n = 30,866), and 21,918 patients from 2012 were used for validation. Age and injury codes were required, and transferred patients were excluded. Logistic regression analysis was applied with hospital mortality as the dependent variable. Results were evaluated in terms of discrimination (area under the receiver operating characteristic curve, AUC), precision (observed versus predicted mortality), and calibration (Hosmer-Lemeshow goodness-of-fit statistic). The mean age of the development population was 47.3 years; 71.6% were males, and the average ISS was 19.3 points. Hospital mortality rate was 11.5% in this group. The new RISC II model consists of the following predictors: worst and second-worst injury (AIS severity level), head injury, age, sex, pupil reactivity and size, pre-injury health status, blood pressure, acidosis (base deficit), coagulation, haemoglobin, and cardiopulmonary resuscitation. Missing values are included as a separate category for every variable. In the development and the validation dataset, the new RISC II outperformed the original RISC score, for example AUC in the development dataset 0.953 versus 0.939. The updated RISC II prognostic score has several advantages over the previous RISC model. Discrimination, precision and calibration are improved, and patients with partial missing values could now be included. Results were confirmed in a validation dataset.

The CMIP5 archive architecture: A system for petabyte-scale distributed archival of climate model data

NASA Astrophysics Data System (ADS)

Pascoe, Stephen; Cinquini, Luca; Lawrence, Bryan

2010-05-01

The Phase 5 Coupled Model Intercomparison Project (CMIP5) will produce a petabyte scale archive of climate data relevant to future international assessments of climate science (e.g., the IPCC's 5th Assessment Report scheduled for publication in 2013). The infrastructure for the CMIP5 archive must meet many challenges to support this ambitious international project. We describe here the distributed software architecture being deployed worldwide to meet these challenges. The CMIP5 architecture extends the Earth System Grid (ESG) distributed architecture of Datanodes, providing data access and visualisation services, and Gateways providing the user interface including registration, search and browse services. Additional features developed for CMIP5 include a publication workflow incorporating quality control and metadata submission, data replication, version control, update notification and production of citable metadata records. Implementation of these features have been driven by the requirements of reliable global access to over 1Pb of data and consistent citability of data and metadata. Central to the implementation is the concept of Atomic Datasets that are identifiable through a Data Reference Syntax (DRS). Atomic Datasets are immutable to allow them to be replicated and tracked whilst maintaining data consistency. However, since occasional errors in data production and processing is inevitable, new versions can be published and users notified of these updates. As deprecated datasets may be the target of existing citations they can remain visible in the system. Replication of Atomic Datasets is designed to improve regional access and provide fault tolerance. Several datanodes in the system are designated replicating nodes and hold replicas of a portion of the archive expected to be of broad interest to the community. Gateways provide a system-wide interface to users where they can track the version history and location of replicas to select the most appropriate location for download. In addition to meeting the immediate needs of CMIP5 this architecture provides a basis for the Earth System Modeling e-infrastructure being further developed within the EU FP7 IS-ENES project.

Advanced Science.

ERIC Educational Resources Information Center

Coles, Mike; Nelms, Rick

1996-01-01

Describes a study that explores the depth and breadth of scientific facts, principles, and procedures which are required in the Advanced General National Vocational Qualifications (GNVQ) science through comparison with GCE Advanced level. The final report takes account of the updated 1996 version of GNVQ science. (DDR)

Description of Updates for MCCEM Version 1.2 (February 2001)

EPA Pesticide Factsheets

The EPA Office of Pollution Prevention and Toxics, Economics, Exposure, and Technology Division has developed several exposure assessment tools and models. A description of the models and tools and the definition of exposure are given in separate web page

Detailed weather and terrain analysis for aircraft noise modeling

DOT National Transportation Integrated Search

2013-04-30

A study has been conducted supporting refinement and development of FAAs airport environmental analysis tools. Tasks conducted in this study are: (1) updated analysis of the 1997 KDEN noise model validation study with newer versions of INM and rel...

The 2006 Kennedy Space Center Range Reference Atmosphere Model Validation Study and Sensitivity Analysis to the Performance of the National Aeronautics and Space Administration's Space Shuttle Vehicle

NASA Technical Reports Server (NTRS)

Burns, Lee; Decker, Ryan; Harrington, Brian; Merry, Carl

2008-01-01

The Kennedy Space Center (KSC) Range Reference Atmosphere (RRA) is a statistical model that summarizes wind and thermodynamic atmospheric variability from surface to 70 km. The National Aeronautics and Space Administration's (NASA) Space Shuttle program, which launches from KSC, utilizes the KSC RRA data to evaluate environmental constraints on various aspects of the vehicle during ascent. An update to the KSC RRA was recently completed. As part of the update, the Natural Environments Branch at NASA's Marshall Space Flight Center (MSFC) conducted a validation study and a comparison analysis to the existing KSC RRA database version 1983. Assessments to the Space Shuttle vehicle ascent profile characteristics were performed by JSC/Ascent Flight Design Division to determine impacts of the updated model to the vehicle performance. Details on the model updates and the vehicle sensitivity analyses with the update model are presented.

GOMMA: a component-based infrastructure for managing and analyzing life science ontologies and their evolution

PubMed Central

2011-01-01

Background Ontologies are increasingly used to structure and semantically describe entities of domains, such as genes and proteins in life sciences. Their increasing size and the high frequency of updates resulting in a large set of ontology versions necessitates efficient management and analysis of this data. Results We present GOMMA, a generic infrastructure for managing and analyzing life science ontologies and their evolution. GOMMA utilizes a generic repository to uniformly and efficiently manage ontology versions and different kinds of mappings. Furthermore, it provides components for ontology matching, and determining evolutionary ontology changes. These components are used by analysis tools, such as the Ontology Evolution Explorer (OnEX) and the detection of unstable ontology regions. We introduce the component-based infrastructure and show analysis results for selected components and life science applications. GOMMA is available at http://dbs.uni-leipzig.de/GOMMA. Conclusions GOMMA provides a comprehensive and scalable infrastructure to manage large life science ontologies and analyze their evolution. Key functions include a generic storage of ontology versions and mappings, support for ontology matching and determining ontology changes. The supported features for analyzing ontology changes are helpful to assess their impact on ontology-dependent applications such as for term enrichment. GOMMA complements OnEX by providing functionalities to manage various versions of mappings between two ontologies and allows combining different match approaches. PMID:21914205

International MODIS and AIRS Processing Package (IMAPP) Implementation of Infusion of Satellite Data into Environmental Applications-International (IDEA-I) for Air Quality Forecasts using Suomi-NPP, Terra and Aqua Aerosol Retrievals

NASA Astrophysics Data System (ADS)

Davies, J. E.; Strabala, K.; Pierce, R. B.; Huang, A.

2016-12-01

Fine mode aerosols play a significant role in public health through their impact on respiratory and cardiovascular disease. IDEA-I (Infusion of Satellite Data into Environmental Applications-International) is a real-time system for trajectory-based forecasts of aerosol dispersion that can assist in the prediction of poor air quality events. We released a direct broadcast version of IDEA-I for aerosol trajectory forecasts in June 2012 under the International MODIS and AIRS Processing Package (IMAPP). In January 2014 we updated this application with website software to display multi-satellite products. Now we have added VIIRS aerosols from Suomi National Polar-orbiting Partnership (S-NPP). IMAPP is a NASA-funded and freely-distributed software package developed at Space Science and Engineering Center of University of Wisconsin-Madison that has over 2,300 registered users worldwide. With IMAPP, any ground station capable of receiving direct broadcast from Terra or Aqua can produce calibrated and geolocated radiances and a suite of environmental products. These products include MODIS AOD required for IDEA-I. VIIRS AOD for IDEA-I can be generated by Community Satellite Processing Package (CSPP) VIIRS EDR Version 2.0 Software for Suomi NPP. CSPP is also developed and distributed by Space Science & Engineering Center. This presentation describes our updated IMAPP implementation of IDEA-I through an example of its operation in a region known for episodic poor air quality events.

VizieR Online Data Catalog: GOODS-MUSIC catalog updated version (Santini+, 2009)

NASA Astrophysics Data System (ADS)

Santini, P.; Fontana, A.; Grazian, A.; Salimbeni, S.; Fiore, F.; Fontanot, F.; Boutsia, K.; Castelllano, M.; Cristiani, S.; de Santis, C.; Gallozzi, S.; Giallongo, E.; Nonino, M.; Menci, N.; Paris, D.; Pentericci, L.; Vanzella, E.

2009-06-01

The GOODS-MUSIC multiwavelength catalog provides photometric and spectroscopic information for galaxies in the GOODS Southern field. It includes two U images obtained with the ESO 2.2m telescope and one U band image from VLT-VIMOS, the ACS-HST images in four optical (B,V,i,z) bands, the VLT-ISAAC J, H, and Ks bands as well as the Spitzer images at 3.6, 4.5, 5.8, and 8 micron (IRAC) and 24 micron (MIPS). Most of these images have been made publicly available in the coadded version by the GOODS team, while the U band data were retrieved in raw format and reduced by our team. We also collected all the available spectroscopic information from public spectroscopic surveys and cross-correlated the spectroscopic redshifts with our photometric catalog. For the unobserved fraction of the objects, we applied our photometric redshift code to obtain well-calibrated photometric redshifts. The final catalog is made up of 15208 objects, with 209 known stars and 61 AGNs. The major new feature of this updated release is the inclusion of 24 micron photometry. Further improvements concern a revised photometry in the four IRAC bands (mainly based on the use of new PSF-matching kernerls and on a revised procedure for estimating the background), the enlargement of the sample of galaxies with spectroscopic redshifts, the addition of objects selected on the IRAC 4.5 micron image and a more careful selection of AGN sources. (1 data file).

Towards improving the efficiency of blowing through a permeable wall and prospects of its use for a flow control

NASA Astrophysics Data System (ADS)

Kornilov, V. I.; Boiko, A. V.

2016-10-01

Modern achievements, status, and prospects of studies on reducing the turbulent friction and aerodynamic drag with the help of the blowing through a permeable wall are discussed. The main focus is placed upon a physical modeling of the process of boundary layer blowing in the framework of the dimensional theory, a critical analysis of experimental and numerical results for different conditions of air blowing through a high-tech finely perforated wall including the case of external-pressure-flow air supply in wind tunnel, and elicitation of the physical mechanisms responsible for the reduction of turbulent friction at flow-exposed surfaces. It is shown that the use of air supply through the micro-perforated wall with low effective roughness, which is manufactured in compliance with the highest necessary requirements to quality and geometry of orifices, is quite a justified means for easy, affordable, and reliable control of near-wall turbulent flows in laboratory experiment and numerical simulation. This approach can provide a sustained reduction of local skin friction coefficient along flat plate, which in some cases reaches 90%. At the request of all authors of the paper and with the agreement of the Proceedings Editor, an updated version of this article was published on 26 October 2016. The original version supplied to AIP Publishing contained a misrepresentation in Figure 1. This has been corrected in the updated and republished article.

DEC/SOL: solution of dense systems of linear algebraic equations. [In Fortran IV and compass for CDC 7600; DECST and SOLST for CDC STAR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hindmarsh, A.C.; Sloan, L.J.; Dubois, P.F.

1978-12-01

This report supersedes the original version, dated June 1976. It describes four versions of a pair of subroutines for solving N x N systems of linear algebraic equations. In each case, the first routine, DEC, performs an LU decomposition of the matrix with partial pivoting, and the second, SOL, computes the solution vector by back-substitution. The first version is in Fortran IV, and is derived from routines DECOMP and SOLVE written by C.B. Moler. The second is a version for the CDC 7600 computer using STACKLIB. The third is a hand-coded (Compass) version for the 7600. The fourth is amore » vectorized version for the CDC STAR, renamed DECST and SOLST. Comparative tests on these routines are also described. The Compass version is faster than the others on the 7600 by factors of up to 5. The major revisions to the original report, and to the subroutines described, are an updated description of the availability of each version of DEC/SOL; correction of some errors in the Compass version, as altered so as to be compatible with FTN; and a new STAR version, which runs much faster than the earlier one. The standard Fortran version, the Fortran/STACKLIB version, and the object code generated from the Compass version and available in STACKLIB have not been changed.« less

Haloperidol for the treatment of nausea and vomiting in palliative care patients.

PubMed

Murray-Brown, Fay; Dorman, Saskie

2015-11-02

Nausea and vomiting are common symptoms in patients with terminal, incurable illnesses. Both nausea and vomiting can be distressing. Haloperidol is commonly prescribed to relieve these symptoms. This is an updated version of the original Cochrane review published in Issue 2, 2009, of Haloperidol for the treatment of nausea and vomiting in palliative care patients. To evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients. For this updated review, we performed updated searches of CENTRAL, EMBASE and MEDLINE in November 2013 and in November 2014. We searched controlled trials registers in March 2015 to identify any ongoing or unpublished trials. We imposed no language restrictions. For the original review, we performed database searching in August 2007, including CENTRAL, MEDLINE, EMBASE, CINAHL and AMED, using relevant search terms and synonyms. Handsearching complemented the electronic searches (using reference lists of included studies, relevant chapters and review articles) for the original review. We considered randomised controlled trials (RCTs) of haloperidol for the treatment of nausea or vomiting, or both, in any setting, for inclusion. The studies had to be conducted with adults receiving palliative care or suffering from an incurable progressive medical condition. We excluded studies where nausea or vomiting, or both, were thought to be secondary to pregnancy or surgery. We imported records from each of the electronic databases into a bibliographic package and merged them into a core database where we inspected titles, keywords and abstracts for relevance. If it was not possible to accept or reject an abstract with certainty, we obtained the full text of the article for further evaluation. The two review authors independently assessed studies in accordance with the inclusion criteria. There were no differences in opinion between the authors with regard to the assessment of studies. We considered 27 studies from the 2007 search. In this update we considered a further 38 studies from the 2013 search, and two in the 2014 search. We identified one RCT of moderate quality with low risk of bias overall which met the inclusion criteria for this update, comparing ABH (Ativan®, Benadryl®, Haldol®) gel, applied to the wrist, with placebo for the relief of nausea in 22 participants. ABH gel includes haloperidol as well as diphenhydramine and lorazepam. The gel was not significantly better than placebo in this small study; however haloperidol is reported not to be absorbed significantly when applied topically, therefore the trial does not address the issue of whether haloperidol is effective or well-tolerated when administered by other routes (e.g. by mouth, subcutaneously or intravenously). We identified one ongoing trial of haloperidol for the management of nausea and vomiting in patients with cancer, with initial results published in a conference abstract suggesting that haloperidol is effective for 65% of patients. The trial had not been fully published at the time of our review. A further trial has opened, comparing oral haloperidol with oral methotrimeprazine (levomepromazine) for patients with cancer and nausea unrelated to their treatment, which we aim to include in the next review update. Since the last version of this review, we found one new study for inclusion but the conclusion remains unchanged. There is incomplete evidence from published RCTs to determine the effectiveness of haloperidol for nausea and vomiting in palliative care. Other than the trial of ABH gel vs placebo, we did not identify any fully published RCTs exploring the effectiveness of haloperidol for nausea and vomiting in palliative care patients for this update, but two trials are underway.

An update of Quaternary faults of central and eastern Oregon

USGS Publications Warehouse

Weldon, Ray J.; Fletcher, D.K.; Weldon, E.M.; Scharer, K.M.; McCrory, P.A.

2002-01-01

This is the online version of a CD-ROM publication. We have updated the eastern portion of our previous active fault map of Oregon (Pezzopane, Nakata, and Weldon, 1992) as a contribution to the larger USGS effort to produce digital maps of active faults in the Pacific Northwest region. The 1992 fault map has seen wide distribution and has been reproduced in essentially all subsequent compilations of active faults of Oregon. The new map provides a substantial update of known active or suspected active faults east of the Cascades. Improvements in the new map include (1) many newly recognized active faults, (2) a linked ArcInfo map and reference database, (3) more precise locations for previously recognized faults on shaded relief quadrangles generated from USGS 30-m digital elevations models (DEM), (4) more uniform coverage resulting in more consistent grouping of the ages of active faults, and (5) a new category of 'possibly' active faults that share characteristics with known active faults, but have not been studied adequately to assess their activity. The distribution of active faults has not changed substantially from the original Pezzopane, Nakata and Weldon map. Most faults occur in the south-central Basin and Range tectonic province that is located in the backarc portion of the Cascadia subduction margin. These faults occur in zones consisting of numerous short faults with similar rates, ages, and styles of movement. Many active faults strongly correlate with the most active volcanic centers of Oregon, including Newberry Craters and Crater Lake.

A new version of the RDP (Ribosomal Database Project)

NASA Technical Reports Server (NTRS)

Maidak, B. L.; Cole, J. R.; Parker, C. T. Jr; Garrity, G. M.; Larsen, N.; Li, B.; Lilburn, T. G.; McCaughey, M. J.; Olsen, G. J.; Overbeek, R.;

Reference coordinate systems: An update. Supplement 11

NASA Technical Reports Server (NTRS)

Mueller, Ivan I.

1988-01-01

A common requirement for all geodetic investigations is a well-defined coordinate system attached to the earth in some prescribed way, as well as a well-defined inertial coordinate system in which the motions of the terrestrial frame can be monitored. The paper deals with the problems encountered when establishing such coordinate systems and the transformations between them. In addition, problems related to the modeling of the deformable earth are discussed. This paper is an updated version of the earlier work, Reference Coordinate Systems for Earth Dynamics: A Preview, by the author.

An update of input instructions to TEMOD

NASA Technical Reports Server (NTRS)

1973-01-01

The theory and operation of a FORTRAN 4 computer code, designated as TEMOD, used to calcuate tubular thermoelectric generator performance is described in WANL-TME-1906. The original version of TEMOD was developed in 1969. A description is given of additions to the mathematical model and an update of the input instructions to the code. Although the basic mathematical model described in WANL-TME-1906 has remained unchanged, a substantial number of input/output options were added to allow completion of module performance parametrics as required in support of the compact thermoelectric converter system technology program.

Organic aerosol sources an partitioning in CMAQv5.2

EPA Science Inventory

We describe a major CMAQ update, available in version 5.2, which explicitly treats the semivolatile mass transfer of primary organic aerosol compounds, in agreement with available field and laboratory observations. Until this model release, CMAQ has considered these compounds to ...

Health Assessment Document for Diesel Exhaust (Revised External Review Draft)

EPA Science Inventory

This External Review Draft version of this assessment updates three earlier drafts (1999, 1998 and 1994) that were reviewed by the Clean Air Scientific Advisory Committee (CASAC) of the Agency's Science Advisory Board (SAB). The assessment characterizes the possible human healt...

Patriot Script 1.0.13 User Guide for PEM 1.3.2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cleland, Timothy James; Kubicek, Deborah Ann; Stroud, Phillip David

2015-11-02

This document provides an updated user guide for Patriot Script Version 1.0.13, for release with PEM 1.3.1 (LAUR-1422817) that adds description and instructions for the new excursion capability (see section 4.5.1).

Long-term pavement performance maintenance and rehabilitation data collection guide

DOT National Transportation Integrated Search

2006-03-01

This document provides guidelines and forms for documenting maintenance and rehabilitation treatments on test sections in the Long-Term Pavement Performance (LTPP) program and is an update to chapters 6 and 7 of the 1993 version of the LTPP Data Coll...

Evaluation of an updated version of the risk awareness and perception training program for young drivers.

DOT National Transportation Integrated Search

2017-03-01

Previous research suggests newly licensed teen drivers often fail to anticipate where unexpected hazards might materialize. One : training program designed to address these apparent deficiencies in knowledge and skills that has shown promise in previ...

MISR Level 3 Radiance Versioning

Atmospheric Science Data Center

2016-11-04

... ESDT Product File Name Prefix Current Quality Designations MIL3DRD, MIL3MRD, MIL3QRD, and MIL3YRD ... Data Product Specification Rev K  (PDF). Update to work with new format of the input PGE 1 files.   F02_0007 ...

Circuit For Control Of Electromechanical Prosthetic Hand

NASA Technical Reports Server (NTRS)

Bozeman, Richard J., Jr.

1995-01-01

Proposed circuit for control of electromechanical prosthetic hand derives electrical control signals from shoulder movements. Updated, electronic version of prosthesis, that includes two hooklike fingers actuated via cables from shoulder harness. Circuit built around favored shoulder harness, provides more dexterous movement, without incurring complexity of computer-controlled "bionic" or hydraulically actuated devices. Additional harness and potentiometer connected to similar control circuit mounted on other shoulder. Used to control stepping motor rotating hand about prosthetic wrist to one of number of angles consistent with number of digital outputs. Finger-control signals developed by circuit connected to first shoulder harness transmitted to prosthetic hand via sliprings at prosthetic wrist joint.

SAMICS: Input data preparation. [Solar Array Manufacturing Industry Costing Standards

NASA Technical Reports Server (NTRS)

Chamberlain, R. G.; Aster, R. W.

1979-01-01

The Solar Array Manufacturing Industry Costing Standards (SAMICS) provide standard formats, data, assumptions, and procedures for estimating the price that a manufacturer would have to charge for the product of a specified manufacturing process sequence. A line-by-line explanation is given of those standard formats which describe the economically important characteristics of the manufacturing processes and the technological structure of the companies and the industry. This revision provides an updated presentation of Format A Process Description, consistent with the October 1978 version of that form. A checklist of items which should be entered on Format A as direct expenses is included.

MOD06 Optical and Microphysical Retrievals

NASA Technical Reports Server (NTRS)

King, Michael D.; Platnick, Steven; Arnold, G. T.; Dinsick, J.; Gatebe, C. K.; Gray, M. A.; Hubanks, P. A.; Moody, E. G.; Wind, B.; Wind, G.

2003-01-01

Major efforts over the past six months included: (1) submission of MOD06 Optical and Microphysical Retrieval recompetition proposal, (2) delivery of a MODIS Atmosphere Level-3 update, (3) delivery of the MODIS Atmosphere s new combined Level-2 product, (4) development of an above-cloud precipitable water research algorithm and a multi-layer cloud detection algorithm, (5) continued development of a Fortran 90 version of the retrieval code for use with MAS as well as operational MODIS processing, (6) preliminary analysis of CRYSTAL-FACE field experiment in July 2002, (7) continued analysis of data obtained during the SAFARI 2000 dry season campaign in southern Africa, and the Arctic FIRE-ACE experiment.

Applying modern psychometric techniques to melodic discrimination testing: Item response theory, computerised adaptive testing, and automatic item generation.

PubMed

Harrison, Peter M C; Collins, Tom; Müllensiefen, Daniel

2017-06-15

Modern psychometric theory provides many useful tools for ability testing, such as item response theory, computerised adaptive testing, and automatic item generation. However, these techniques have yet to be integrated into mainstream psychological practice. This is unfortunate, because modern psychometric techniques can bring many benefits, including sophisticated reliability measures, improved construct validity, avoidance of exposure effects, and improved efficiency. In the present research we therefore use these techniques to develop a new test of a well-studied psychological capacity: melodic discrimination, the ability to detect differences between melodies. We calibrate and validate this test in a series of studies. Studies 1 and 2 respectively calibrate and validate an initial test version, while Studies 3 and 4 calibrate and validate an updated test version incorporating additional easy items. The results support the new test's viability, with evidence for strong reliability and construct validity. We discuss how these modern psychometric techniques may also be profitably applied to other areas of music psychology and psychological science in general.

The Lunar Mapping and Modeling Project Update

NASA Technical Reports Server (NTRS)

Noble, S.; French, R.; Nall, M.; Muery, K.

2010-01-01

The Lunar Mapping and Modeling Project (LMMP) is managing the development of a suite of lunar mapping and modeling tools and data products that support lunar exploration activities, including the planning, design, development, test, and operations associated with crewed and/or robotic operations on the lunar surface. In addition, LMMP should prove to be a convenient and useful tool for scientific analysis and for education and public outreach (E/PO) activities. LMMP will utilize data predominately from the Lunar Reconnaissance Orbiter, but also historical and international lunar mission data (e.g. Lunar Prospector, Clementine, Apollo, Lunar Orbiter, Kaguya, and Chandrayaan-1) as available and appropriate. LMMP will provide such products as image mosaics, DEMs, hazard assessment maps, temperature maps, lighting maps and models, gravity models, and resource maps. We are working closely with the LRO team to prevent duplication of efforts and ensure the highest quality data products. A beta version of the LMMP software was released for limited distribution in December 2009, with the public release of version 1 expected in the Fall of 2010.

A review and update of the NASA aircraft noise prediction program propeller analysis system

NASA Technical Reports Server (NTRS)

Golub, Robert A.; Nguyen, L. Cathy

1989-01-01

The National Aeronautics and Space Administration (NASA) Aircraft Noise Prediction Program (ANOPP) Propeller Analysis System (PAS) is a set of computational modules for predicting the aerodynamics, performance, and noise of propellers. The ANOPP PAS has the capability to predict noise levels for propeller aircraft certification and produce parametric scaling laws for the adjustment of measured data to reference conditions. A technical overview of the prediction techniques incorporated into the system is presented. The prediction system has been applied to predict the noise signature of a variety of propeller configurations including the effects of propeller angle of attack. A summary of these validation studies is discussed with emphasis being placed on the wind tunnel and flight test programs sponsored by the Federal Aviation Administration (FAA) for the Piper Cherokee Lance aircraft. A number of modifications and improvements have been made to the system and both DEC VAX and IBM-PC versions of the system have been added to the original CDC NOS version.

HELAC-Onia 2.0: An upgraded matrix-element and event generator for heavy quarkonium physics

NASA Astrophysics Data System (ADS)

Shao, Hua-Sheng

2016-01-01

We present an upgraded version (denoted as version 2.0) of the program HELAC-ONIA for the automated computation of heavy-quarkonium helicity amplitudes within non-relativistic QCD framework. The new code has been designed to include many new and useful features for practical phenomenological simulations. It is designed for job submissions under cluster environment for parallel computations via PYTHON scripts. We have interfaced HELAC-ONIA to the parton shower Monte Carlo programs PYTHIA 8 and QEDPS to take into account the parton-shower effects. Moreover, the decay module guarantees that the program can perform the spin-entangled (cascade-)decay of heavy quarkonium after its generation. We have also implemented a reweighting method to automatically estimate the uncertainties from renormalization and/or factorization scales as well as parton-distribution functions to weighted or unweighted events. A further update is the possibility to generate one-dimensional or two-dimensional plots encoded in the analysis files on the fly. Some dedicated examples are given at the end of the writeup.

ChEMBL web services: streamlining access to drug discovery data and utilities.

PubMed

Davies, Mark; Nowotka, Michał; Papadatos, George; Dedman, Nathan; Gaulton, Anna; Atkinson, Francis; Bellis, Louisa; Overington, John P

2015-07-01

ChEMBL is now a well-established resource in the fields of drug discovery and medicinal chemistry research. The ChEMBL database curates and stores standardized bioactivity, molecule, target and drug data extracted from multiple sources, including the primary medicinal chemistry literature. Programmatic access to ChEMBL data has been improved by a recent update to the ChEMBL web services (version 2.0.x, https://www.ebi.ac.uk/chembl/api/data/docs), which exposes significantly more data from the underlying database and introduces new functionality. To complement the data-focused services, a utility service (version 1.0.x, https://www.ebi.ac.uk/chembl/api/utils/docs), which provides RESTful access to commonly used cheminformatics methods, has also been concurrently developed. The ChEMBL web services can be used together or independently to build applications and data processing workflows relevant to drug discovery and chemical biology. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

Geodesy- and geology-based slip-rate models for the Western United States (excluding California) national seismic hazard maps

USGS Publications Warehouse

Petersen, Mark D.; Zeng, Yuehua; Haller, Kathleen M.; McCaffrey, Robert; Hammond, William C.; Bird, Peter; Moschetti, Morgan; Shen, Zhengkang; Bormann, Jayne; Thatcher, Wayne

2014-01-01

The 2014 National Seismic Hazard Maps for the conterminous United States incorporate additional uncertainty in fault slip-rate parameter that controls the earthquake-activity rates than was applied in previous versions of the hazard maps. This additional uncertainty is accounted for by new geodesy- and geology-based slip-rate models for the Western United States. Models that were considered include an updated geologic model based on expert opinion and four combined inversion models informed by both geologic and geodetic input. The two block models considered indicate significantly higher slip rates than the expert opinion and the two fault-based combined inversion models. For the hazard maps, we apply 20 percent weight with equal weighting for the two fault-based models. Off-fault geodetic-based models were not considered in this version of the maps. Resulting changes to the hazard maps are generally less than 0.05 g (acceleration of gravity). Future research will improve the maps and interpret differences between the new models.

A Case Study in Flight Computer Software Redesign

NASA Astrophysics Data System (ADS)

Shimoni, R.; Ben-Zur, Y.

2004-06-01

Historically many real-time systems were developed using technologies that are now obsolete. There is a need for upgrading these systems. A good development process is essential to achieve a well-designed software product. We, at MLM, a subsidary of Israel Aircraft Industries, faced a similar situation in the Flight Mission Computer (Main Airborne Computer-MAC) of the SHAVIT launcher. It was necessary to upgrade the computer hardware and we decided to update the software as well. During the last two years, we have designed and implemented and new version of the MAC software, to be run on a new and stronger target platform. We undertook to create a new version of the MAC program using modern software development techniques. The process included Object-Oriented design using a CASE tool suitable for embedded real-time systems. We have partially implemented the ROPES development process. In this article we present the difficulties and challenges we faced in the software development process.

Dual nozzle design update. [on liquid rocket engines for advanced earth-to-orbit transportation systems

NASA Technical Reports Server (NTRS)

Obrien, C. J.

1982-01-01

Dual-nozzle engines, such as the dual-throat and dual-expander engines, are being evaluated for advanced earth-to-orbit transportation systems. Potential derivatives of the Space Shuttle and completely new vehicles might benefit from these advanced engines. In this paper, progress in the design of single-fuel and dual-fuel dual-nozzle engines is summarized. Dual-nozzle engines include those burning propellants such as LOX/RP-1/LH2, LOX/LC3H8/LH2, LOX/LCH4/LH2, LOX/LH2/LH2, LOX/LCH4/LCH4, LOX/LC3H8/C3H8 and N2O4/MMH/LH2. Engine data are applicable for thrust levels from 200,000 through 670,000 lbF. The results indicate that several versions of these engines utilize state-of-the-art technology and that even advanced versions of these engines do not require a major breakthrough in technology.

Sickle cell disease

PubMed Central

2016-01-01

Introduction Sickle cell disease causes chronic haemolytic anaemia, dactylitis, and painful acute crises. It also increases the risk of stroke, organ damage, bacterial infections, and complications of blood transfusion. In sub-Saharan Africa, up to one third of adults are carriers of the defective sickle cell gene, and 1% to 2% of babies are born with the disease. Methods and outcomes We conducted a systematic overview, aiming to answer the following clinical question: What are the effects of pharmaceutical interventions to prevent sickle cell crisis and other acute complications in people with sickle cell disease? We searched: Medline, Embase, The Cochrane Library, and other important databases up to January 2015 (BMJ Clinical Evidence overviews are updated periodically; please check our website for the most up-to-date version of this overview). Results At this update, searching of electronic databases retrieved 369 studies. After deduplication and removal of conference abstracts, 136 records were screened for inclusion in the overview. Appraisal of titles and abstracts led to the exclusion of 99 studies and the further review of 37 full publications. Of the 37 full articles evaluated, three already included systematic reviews were updated, two systematic reviews, two RCTs, and one subsequent RCT were added at this update. We performed a GRADE evaluation for 12 PICO combinations. Conclusions In this systematic overview, we categorised the efficacy for five interventions based on information about the effectiveness and safety of antibiotic prophylaxis in children aged under 5 years, antibiotic prophylaxis in children aged 5 years or older, hydroxyurea, malaria chemoprophylaxis, and pneumococcal vaccines. PMID:26808098

Compilation of streamflow statistics calculated from daily mean streamflow data collected during water years 1901–2015 for selected U.S. Geological Survey streamgages

USGS Publications Warehouse

Granato, Gregory E.; Ries, Kernell G.; Steeves, Peter A.

2017-10-16

Streamflow statistics are needed by decision makers for many planning, management, and design activities. The U.S. Geological Survey (USGS) StreamStats Web application provides convenient access to streamflow statistics for many streamgages by accessing the underlying StreamStatsDB database. In 2016, non-interpretive streamflow statistics were compiled for streamgages located throughout the Nation and stored in StreamStatsDB for use with StreamStats and other applications. Two previously published USGS computer programs that were designed to help calculate streamflow statistics were updated to better support StreamStats as part of this effort. These programs are named “GNWISQ” (Get National Water Information System Streamflow (Q) files), updated to version 1.1.1, and “QSTATS” (Streamflow (Q) Statistics), updated to version 1.1.2.Statistics for 20,438 streamgages that had 1 or more complete years of record during water years 1901 through 2015 were calculated from daily mean streamflow data; 19,415 of these streamgages were within the conterminous United States. About 89 percent of the 20,438 streamgages had 3 or more years of record, and about 65 percent had 10 or more years of record. Drainage areas of the 20,438 streamgages ranged from 0.01 to 1,144,500 square miles. The magnitude of annual average streamflow yields (streamflow per square mile) for these streamgages varied by almost six orders of magnitude, from 0.000029 to 34 cubic feet per second per square mile. About 64 percent of these streamgages did not have any zero-flow days during their available period of record. The 18,122 streamgages with 3 or more years of record were included in the StreamStatsDB compilation so they would be available via the StreamStats interface for user-selected streamgages. All the statistics are available in a USGS ScienceBase data release.

Global Soil Moisture Estimation through a Coupled CLM4-RTM-DART Land Data Assimilation System

NASA Astrophysics Data System (ADS)

Zhao, L.; Yang, Z. L.; Hoar, T. J.

2016-12-01

Very few frameworks exist that estimate global-scale soil moisture through microwave land data assimilation (DA). Toward this goal, we have developed such a framework by linking the Community Land Model version 4 (CLM4) and a microwave radiative transfer model (RTM) with the Data Assimilation Research Testbed (DART). The deterministic Ensemble Adjustment Kalman Filter (EAKF) within the DART is utilized to estimate global multi-layer soil moisture by assimilating brightness temperature observations from the Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E). A 40-member of Community Atmosphere Model version 4 (CAM4) reanalysis is adopted to drive CLM4 simulations. Spatial-specific time-invariant microwave parameters are pre-calibrated to minimize uncertainties in RTM. Besides, various methods are designed in consideration of computational efficiency. A series of experiments are conducted to quantify the DA sensitivity to microwave parameters, choice of assimilated observations, and different CLM4 updating schemes. Evaluation results indicate that the newly established CLM4-RTM-DART framework improves the open-loop CLM4 simulated soil moisture. Pre-calibrated microwave parameters, rather than their default values, can ensure a more robust global-scale performance. In addition, updating near-surface soil moisture is capable of improving soil moisture in deeper layers, while simultaneously updating multi-layer soil moisture fails to obtain intended improvements. We will show in this presentation the architecture of the CLM4-RTM-DART system and the evaluations on AMSR-E DA. Preliminary results on multi-sensor DA that integrates various satellite observations including GRACE, MODIS, and AMSR-E will also be presented. ReferenceZhao, L., Z.-L. Yang, and T. J. Hoar, 2016. Global Soil Moisture Estimation by Assimilating AMSR-E Brightness Temperatures in a Coupled CLM4-RTM-DART System. Journal of Hydrometeorology, DOI: 10.1175/JHM-D-15-0218.1.

Performance of the G4 Xpert® MTB/RIF assay for the detection of Mycobacterium tuberculosis and rifampin resistance: a retrospective case-control study of analytical and clinical samples from high- and low-tuberculosis prevalence settings.

PubMed

Dharan, Nila J; Blakemore, Robert; Sloutsky, Alex; Kaur, Devinder; Alexander, Richard C; Ghajar, Minoo; Musser, Kimberlee A; Escuyer, Vincent E; Rowlinson, Marie-Claire; Crowe, Susanne; Laniado-Laborin, Rafael; Valli, Eloise; Nabeta, Pamela; Johnson, Pamela; Alland, David

2016-12-20

The Xpert ® MTB/RIF (Xpert) assay is a rapid PCR-based assay for the detection of Mycobacterium tuberculosis complex DNA (MTBc) and mutations associated with rifampin resistance (RIF). An updated version introduced in 2011, the G4 Xpert, included modifications to probe B and updated analytic software. An analytical study was performed to assess Xpert detection of mutations associated with rifampin resistance in rifampin-susceptible and -resistant isolates. A clinical study was performed in which specimens from US and non-US persons suspected of tuberculosis (TB) were tested to determine Xpert performance characteristics. All specimens underwent smear microscopy, mycobacterial culture, conventional drug-susceptibility testing and Xpert testing; DNA from isolates with discordant rifampin resistance results was sequenced. Among 191 laboratory-prepared isolates in the analytical study, Xpert sensitivity for detection of rifampin resistance associated mutations was 97.7% and specificity was 90.8%, which increased to 99.0% after DNA sequencing analysis of the discordant samples. Of the 1,096 subjects in the four clinical studies, 49% were from the US. Overall, Xpert detected MTBc in 439 of 468 culture-positive specimens for a sensitivity of 93.8% (95% confidence interval [CI]: 91.2%-95.7%) and did not detect MTBc in 620 of 628 culture-negative specimens for a specificity of 98.7% (95% CI: 97.5%-99.4%). Sensitivity was 99.7% among smear-positive cases, and 76.1% among smear-negative cases. Non-determinate MTBc detection and false-positive RIF resistance results were low (1.2 and 0.9%, respectively). The updated Xpert assay retained the high sensitivity and specificity of the previous assay versions and demonstrated low rates of non-determinate and RIF resistance false positive results.

Argonne's Michael Wang talks about the GREET Model for reducing vehicle emi

ScienceCinema

Wang, Michael

2018-05-11

To fully evaluate energy and emission impacts of advanced vehicle technologies and new transportation fuels, the fuel cycle from wells to wheels and the vehicle cycle through material recovery and vehicle disposal need to be considered. Sponsored by the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy (EERE), Argonne has developed a full life-cycle model called GREET (Greenhouse gases, Regulated Emissions, and Energy use in Transportation). It allows researchers and analysts to evaluate various vehicle and fuel combinations on a full fuel-cycle/vehicle-cycle basis. The first version of GREET was released in 1996. Since then, Argonne has continued to update and expand the model. The most recent GREET versions are the GREET 1 2012 version for fuel-cycle analysis and GREET 2.7 version for vehicle-cycle analysis.

RADS Version 4: An Efficient Way to Analyse the Multi-Mission Altimeter Database

NASA Astrophysics Data System (ADS)

Scharroo, Remko; Leuliette, Eric; Naeije, Marc; Martin-Puig, Cristina; Pires, Nelson

2016-08-01

The Radar Altimeter Database System (RADS) has grown to become a mature altimeter database. Over the last 18 years it is continuously being developed, first at Delft University of Technology, now also at the National Oceanic and Atmospheric Administration (NOAA) and the European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT).RADS now serves as a fundamental Climate Data Record for sea level. Because of the multiple users involved in vetting the data and the regular updates to the database, RADS is one of the most accurate and complete databases of satellite altimeter data around.RADS version 4 is a major change from the previous version. While the database is compatible with both software versions, the new software provides new tools, allows easier expansion, and has a better and more standardised interface.

Extended Reconstructed Sea Surface Temperature Version 5 (ERSSTv5): Upgrades, Validations, and Intercomparisons

NASA Astrophysics Data System (ADS)

Huang, B.; Thorne, P.; Banzon, P. V. F.; Chepurin, G. A.; Lawrimore, J. H.; Menne, M. J.; Vose, R. S.; Smith, T. M.; Zhang, H. M.

2017-12-01

The monthly global 2°×2° Extended Reconstructed Sea Surface Temperature (ERSST) has been revised and updated from version 4 to version 5. This update incorporates a new release of ICOADS R3.0, a decade of near-surface data from Argo floats, and a new estimate of centennial sea-ice from HadISST2. A number of choices in aspects of quality control, bias adjustment and interpolation have been substantively revised. The resulting ERSST estimates have more realistic spatio-temporal variations, better representation of high latitude SSTs, and ship SST biases are now calculated relative to more accurate buoy measurements, while the global long-term trend remains about the same. Progressive experiments have been undertaken to highlight the effects of each change in data source and analysis technique upon the final product. The reconstructed SST is systematically decreased by 0.077°C, as the reference data source is switched from ship SST in v4 to modern buoy SST in v5. Furthermore, high latitude SSTs are decreased by 0.1°-0.2°C by using sea-ice concentration from HadISST2 over HadISST1. Changes arising from remaining innovations are mostly important at small space and time scales, primarily having an impact where and when input observations are sparse. Cross-validations and verifications with independent modern observations show that the updates incorporated in ERSSTv5 have improved the representation of spatial variability over the global oceans, the magnitude of El Niño and La Niña events, and the decadal nature of SST changes over 1930s-40s when observation instruments changed rapidly. Both long (1900-2015) and short (2000-2015) term SST trends in ERSSTv5 remain significant as in ERSSTv4.

ADAS Update and Maintainability

NASA Technical Reports Server (NTRS)

Watson, Leela R.

2010-01-01

Since 2000, both the National Weather Service Melbourne (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LOIS) as part of their forecast and warning operations. The original LOIS was developed by the Applied Meteorology Unit (AMU) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (AD AS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features. Over the years, the LDIS has become problematic to maintain since it depends on AMU-developed shell scripts that were written for an earlier version of the ADAS software. The goals of this task were to update the NWS MLB/SMG LDIS with the latest version of ADAS, incorporate new sources of observational data, and upgrade and modify the AMU-developed shell scripts written to govern the system. In addition, the previously developed ADAS graphical user interface (GUI) was updated. Operationally, these upgrades will result in more accurate depictions of the current local environment to help with short-range weather forecasting applications, while also offering an improved initialization for local versions of the Weather Research and Forecasting (WRF) model used by both groups.

Current Status of Japan's Activity for GPM/DPR and Global Rainfall Map algorithm development

NASA Astrophysics Data System (ADS)

Kachi, M.; Kubota, T.; Yoshida, N.; Kida, S.; Oki, R.; Iguchi, T.; Nakamura, K.

2012-04-01

The Global Precipitation Measurement (GPM) mission is composed of two categories of satellites; 1) a Tropical Rainfall Measuring Mission (TRMM)-like non-sun-synchronous orbit satellite (GPM Core Observatory); and 2) constellation of satellites carrying microwave radiometer instruments. The GPM Core Observatory carries the Dual-frequency Precipitation Radar (DPR), which is being developed by the Japan Aerospace Exploration Agency (JAXA) and the National Institute of Information and Communications Technology (NICT), and microwave radiometer provided by the National Aeronautics and Space Administration (NASA). GPM Core Observatory will be launched in February 2014, and development of algorithms is underway. DPR Level 1 algorithm, which provides DPR L1B product including received power, will be developed by the JAXA. The first version was submitted in March 2011. Development of the second version of DPR L1B algorithm (Version 2) will complete in March 2012. Version 2 algorithm includes all basic functions, preliminary database, HDF5 I/F, and minimum error handling. Pre-launch code will be developed by the end of October 2012. DPR Level 2 algorithm has been developing by the DPR Algorithm Team led by Japan, which is under the NASA-JAXA Joint Algorithm Team. The first version of GPM/DPR Level-2 Algorithm Theoretical Basis Document was completed on November 2010. The second version, "Baseline code", was completed in January 2012. Baseline code includes main module, and eight basic sub-modules (Preparation module, Vertical Profile module, Classification module, SRT module, DSD module, Solver module, Input module, and Output module.) The Level-2 algorithms will provide KuPR only products, KaPR only products, and Dual-frequency Precipitation products, with estimated precipitation rate, radar reflectivity, and precipitation information such as drop size distribution and bright band height. It is important to develop algorithm applicable to both TRMM/PR and KuPR in order to produce long-term continuous data set. Pre-launch code will be developed by autumn 2012. Global Rainfall Map algorithm has been developed by the Global Rainfall Map Algorithm Development Team in Japan. The algorithm succeeded heritages of the Global Satellite Mapping for Precipitation (GSMaP) project between 2002 and 2007, and near-real-time version operating at JAXA since 2007. "Baseline code" used current operational GSMaP code (V5.222,) and development completed in January 2012. Pre-launch code will be developed by autumn 2012, including update of database for rain type classification and rain/no-rain classification, and introduction of rain-gauge correction.

Implementation of NGA-West2 ground motion models in the 2014 U.S. National Seismic Hazard Maps

USGS Publications Warehouse

Rezaeian, Sanaz; Petersen, Mark D.; Moschetti, Morgan P.; Powers, Peter; Harmsen, Stephen C.; Frankel, Arthur D.

2014-01-01

The U.S. National Seismic Hazard Maps (NSHMs) have been an important component of seismic design regulations in the United States for the past several decades. These maps present earthquake ground shaking intensities at specified probabilities of being exceeded over a 50-year time period. The previous version of the NSHMs was developed in 2008; during 2012 and 2013, scientists at the U.S. Geological Survey have been updating the maps based on their assessment of the “best available science,” resulting in the 2014 NSHMs. The update includes modifications to the seismic source models and the ground motion models (GMMs) for sites across the conterminous United States. This paper focuses on updates in the Western United States (WUS) due to the use of new GMMs for shallow crustal earthquakes in active tectonic regions developed by the Next Generation Attenuation (NGA-West2) project. Individual GMMs, their weighted combination, and their impact on the hazard maps relative to 2008 are discussed. In general, the combined effects of lower medians and increased standard deviations in the new GMMs have caused only small changes, within 5–20%, in the probabilistic ground motions for most sites across the WUS compared to the 2008 NSHMs.

Update on the Health Services Research Doctoral Core Competencies.

PubMed

Burgess, James F; Menachemi, Nir; Maciejewski, Matthew L

2018-03-13

To present revised core competencies for doctoral programs in health services research (HSR), modalities to deliver these competencies, and suggested methods for assessing mastery of these competencies. Core competencies were originally developed in 2005, updated (but unpublished) in 2008, modestly updated for a 2016 HSR workforce conference, and revised based on feedback from attendees. Additional feedback was obtained from doctoral program directors, employer/workforce experts and attendees of presentation on these competencies at the AcademyHealth's June 2017 Annual Research Meeting. The current version (V2.1) competencies include the ethical conduct of research, conceptual models, development of research questions, study designs, data measurement and collection methods, statistical methods for analyzing data, professional collaboration, and knowledge dissemination. These competencies represent a core that defines what HSR researchers should master in order to address the complexities of microsystem to macro-system research that HSR entails. There are opportunities to conduct formal evaluation of newer delivery modalities (e.g., flipped classrooms) and to integrate new Learning Health System Researcher Core Competencies, developed by AHRQ, into the HSR core competencies. Core competencies in HSR are a continually evolving work in progress because new research questions arise, new methods are developed, and the trans-disciplinary nature of the field leads to new multidisciplinary and team building needs. © Health Research and Educational Trust.

DNAStat, version 2.1--a computer program for processing genetic profile databases and biostatistical calculations.

PubMed

Berent, Jarosław

2010-01-01

This paper presents the new DNAStat version 2.1 for processing genetic profile databases and biostatistical calculations. The popularization of DNA studies employed in the judicial system has led to the necessity of developing appropriate computer programs. Such programs must, above all, address two critical problems, i.e. the broadly understood data processing and data storage, and biostatistical calculations. Moreover, in case of terrorist attacks and mass natural disasters, the ability to identify victims by searching related individuals is very important. DNAStat version 2.1 is an adequate program for such purposes. The DNAStat version 1.0 was launched in 2005. In 2006, the program was updated to 1.1 and 1.2 versions. There were, however, slight differences between those versions and the original one. The DNAStat version 2.0 was launched in 2007 and the major program improvement was an introduction of the group calculation options with the potential application to personal identification of mass disasters and terrorism victims. The last 2.1 version has the option of language selection--Polish or English, which will enhance the usage and application of the program also in other countries.

LANDFIRE 2010 - updated data to support wildfire and ecological management

USGS Publications Warehouse

Nelson, Kurtis J.; Connot, Joel A.; Peterson, Birgit E.; Picotte, Joshua J.

2013-01-01

Wildfire is a global phenomenon that affects human populations and ecosystems. Wildfire effects occur at local to global scales impacting many people in different ways (Figure 1). Ecological concerns due to land use, fragmentation, and climate change impact natural resource use, allocation, and conservation. Access to consistent and current environmental data is a constant challenge, yet necessary for understanding the complexities of wildfire and ecological management. Data products and tools from the LANDFIRE Program help decision-makers to clarify problems and identify possible solutions when managing fires and natural resources. LANDFIRE supports the reduction of risk from wildfire to human lives and property, monitoring of fire danger, prediction of fire behavior on active incidents, and assessment of fire severity and impacts on natural systems [1] [2] [3]. LANDFIRE products are unique in that they are nationally consistent and provide the only complete geospatial dataset describing vegetation and wildland fuel information for the entire U.S. As such, LANDFIRE data are useful for many ecological applications [3]. For example, LANDFIRE data were recently integrated into a decision-support system for resource management and conservation decision-making along the Appalachian Trail. LANDFIRE is a joint effort between the U.S. Department of the Interior Office of Wildland Fire, U.S. Department of Agriculture Forest Service Fire & Aviation Management, and The Nature Conservancy. To date, seven versions of LANDFIRE data have been released, with each successive version improving the quality of the data, adding additional features, and/or updating the time period represented by the data. The latest version, LANDFIRE 2010 (LF 2010), released mid-2013, represents circa 2010 landscape conditions and succeeds LANDFIRE 2008 (LF 2008), which represented circa 2008 landscape conditions. LF 2010 used many of the same processes developed for the LF 2008 effort [3]. Ongoing refinement of the LANDFIRE vegetation and fuel data is necessary to improve the quality and usability of the data and to capture landscape disturbance. LANDFIRE relies on Landsat multi-spectral imagery to produce and update vegetation and fuel data. The deep Landsat archive provides data needed for vegetation classification, change analysis, and historical disturbance characterization, for which LANDFIRE has used more than 24,000 image scenes since the program’s inception. In addition, LF 2010 used airborne and spaceborne lidar, and spaceborne synthetic aperture radar (SAR) to map vegetation structure in areas where ground-based field information was lacking, including Alaska and U.S.-affiliated islands in the Caribbean and the Pacific. The mapping of insular areas is new for the 2010 data release; previous versions of LANDFIRE were limited to the conterminous U.S., Alaska, and Hawaii.

Situation awareness in airway facilities : replacement of maintenance control centers with operations control centers.

DOT National Transportation Integrated Search

2000-01-01

This document contains an updated and expanded version of the Automation chapter of the Human Factors Design Guide. A research team of human factors experts evaluated the existing guidelines for relevance, clarity, and usability. The research team dr...

Repair and protection of hydraulic cement concrete bridge decks.

DOT National Transportation Integrated Search

1994-01-01

The report is an updated version of "A Manual for the Repair and Protection of Hydraulic Cement Concrete Bridge Decks" (VTRC 90-TAR2). The report was prepared for Chapter 2 of the Hydraulic Cement Concrete Construction School Study Guide which is dis...

Open Source Surrogate Safety Assessment Model, 2017 Enhancement and Update: SSAM Version 3.0 [Tech Brief

DOT National Transportation Integrated Search

2016-11-17

The ETFOMM (Enhanced Transportation Flow Open Source Microscopic Model) Cloud Service (ECS) is a software product sponsored by the U.S. Department of Transportation in conjunction with the Microscopic Traffic Simulation Models and SoftwareAn Op...

The PTA TV Trainer's Manual.

ERIC Educational Resources Information Center

National PTA, Chicago, IL.

This updated version of a 1977 manual provides information about the television industry, communications regulations, and citizen recourse to improper broadcasting procedures for use in training Parent Teacher Association (PTA) volunteers to work for effective change within the television industry. The first section discusses the operations of the…

Impact of edge lines on safety of rural two-lane highways.

DOT National Transportation Integrated Search

2005-10-01

This report documents the results of the project for Impact of Edge Lines on Safety of Rural Two Lane Highways. This research project was initiated in the effort of compliance with the updated version of the Manual on Uniform Traffic Control De...

Road weather information system environmental sensor station siting guide, version 2.0

DOT National Transportation Integrated Search

2008-11-01

FHWA initiated an effort in 2007 to evaluate and update, as necessary the ESS Guidelines first published in 2004 (FHWA-HOP-05-026). This effort is summarized in a companion report Implementation and Evaluation of RWIS ESS Siting Guidelines. The...

An ocean data assimilation system and reanalysis of the World Ocean hydrophysical fields

NASA Astrophysics Data System (ADS)

Zelenko, A. A.; Vil'fand, R. M.; Resnyanskii, Yu. D.; Strukov, B. S.; Tsyrulnikov, M. D.; Svirenko, P. I.

2016-07-01

A new version of the ocean data assimilation system (ODAS) developed at the Hydrometcentre of Russia is presented. The assimilation is performed following the sequential scheme analysis-forecast-analysis. The main components of the ODAS are procedures for operational observation data processing, a variational analysis scheme, and an ocean general circulation model used to estimate the first guess fields involved in the analysis. In situ observations of temperature and salinity in the upper 1400-m ocean layer obtained from various observational platforms are used as input data. In the new ODAS version, the horizontal resolution of the assimilating model and of the output products is increased, the previous 2D-Var analysis scheme is replaced by a more general 3D-Var scheme, and a more flexible incremental analysis updating procedure is introduced to correct the model calculations. A reanalysis of the main World Ocean hydrophysical fields over the 2005-2015 period has been performed using the updated ODAS. The reanalysis results are compared with data from independent sources.

The European Federation of Organisations for Medical Physics Policy Statement No. 6.1: Recommended Guidelines on National Registration Schemes for Medical Physicists.

PubMed

Christofides, Stelios; Isidoro, Jorge; Pesznyak, Csilla; Bumbure, Lada; Cremers, Florian; Schmidt, Werner F O

2016-01-01

This EFOMP Policy Statement is an update of Policy Statement No. 6 first published in 1994. The present version takes into account the European Union Parliament and Council Directive 2013/55/EU that amends Directive 2005/36/EU on the recognition of professional qualifications and the European Union Council Directive 2013/59/EURATOM laying down the basic safety standards for protection against the dangers arising from exposure to ionising radiation. The European Commission Radiation Protection Report No. 174, Guidelines on Medical Physics Expert and the EFOMP Policy Statement No. 12.1, Recommendations on Medical Physics Education and Training in Europe 2014, are also taken into consideration. The EFOMP National Member Organisations are encouraged to update their Medical Physics registration schemes where these exist or to develop registration schemes taking into account the present version of this EFOMP Policy Statement (Policy Statement No. 6.1"Recommended Guidelines on National Registration Schemes for Medical Physicists"). Copyright © 2016. Published by Elsevier Ltd.

Summary: Update to ASTM guide E 1523 to charge control and charge referencing techniques in x-ray photoelectron spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baer, D.R.

2005-05-01

An updated version of the American Society for Testing and Materials (ASTM) guide E 1523 to the methods to charge control and charge referencing techniques in x-ray photoelectron spectroscopy has been released by ASTM [Annual Book of ASTM Standards Surface Analysis (American Society for Testing and Materials, West Conshohocken, PA, 2004), Vol. 03.06]. The guide is meant to acquaint x-ray photoelectron spectroscopy (XPS) users with the various charge control and charge referencing techniques that are and have been used in the acquisition and interpretation of XPS data from surfaces of insulating specimens. The current guide has been expanded to includemore » new references as well as recommendations for reporting information on charge control and charge referencing. The previous version of the document had been published in 1997 [D. R. Baer and K. D. Bomben, J. Vac. Sci. Technol. A 16, 754 (1998)].« less

Using PIDs to Support the Full Research Data Publishing Lifecycle

NASA Astrophysics Data System (ADS)

Waard, A. D.

2016-12-01

Persistent identifiers can help support scientific research, track scientific impact and let researchers achieve recognition for their work. We discuss a number of ways in which Elsevier utilizes PIDs to support the scholarly lifecycle: To improve the process of storing and sharing data, Mendeley Data (http://data.mendeley.com) makes use of persistent identifiers to support the dynamic nature of data and software, by tracking and recording the provenance and versioning of datasets. This system now allows the comparison of different versions of a dataset, to see precisely what was changed during a versioning update. To present research data in context for the reader, we include PIDs in research articles as hyperlinks: https://www.elsevier.com/books-and-journals/content-innovation/data-base-linking. In some cases, PIDs fetch data files from the repositories provide that allow the embedding of visualizations, e.g. with PANGAEA and PubChem: https://www.elsevier.com/books-and-journals/content-innovation/protein-viewer; https://www.elsevier.com/books-and-journals/content-innovation/pubchem. To normalize referenced data elements, the Resource Identification Initiative - which we developed together with members of the Force11 RRID group - introduces a unified standard for resource identifiers (RRIDs) that can easily be interpreted by both humans and text mining tools. https://www.force11.org/group/resource-identification-initiative/update-resource-identification-initiative, as can be seen in our Antibody Data app: https://www.elsevier.com/books-and-journals/content-innovation/antibody-data To enable better citation practices and support robust metrics system for sharing research data, we have helped develop, and are early adopters of the Force11 Data Citation Principles and Implementation groups (https://www.force11.org/group/dcip) Lastly, through our work with the Research Data Alliance Publishing Data Services group, we helped create a set of guidelines (http://www.scholix.org/guidelines) and a demonstrator service (http://dliservice.research-infrastructures.eu/#/) for a linked data network connecting datasets, articles, and individuals, which all rely on robust PIDs.

Using Mobile App Development Tools to Build a GIS Application

NASA Astrophysics Data System (ADS)

Mital, A.; Catchen, M.; Mital, K.

2014-12-01

Our group designed and built working web, android, and IOS applications using different mapping libraries as bases on which to overlay fire data from NASA. The group originally planned to make app versions for Google Maps, Leaflet, and OpenLayers. However, because the Leaflet library did not properly load on Android, the group focused efforts on the other two mapping libraries. For Google Maps, the group first designed a UI for the web app and made a working version of the app. After updating the source of fire data to one which also provided historical fire data, the design had to be modified to include the extra data. After completing a working version of the web app, the group used webview in android, a built in resource which allowed porting the web app to android without rewriting the code for android. Upon completing this, the group found Apple IOS devices had a similar capability, and so decided to add an IOS app to the project using a function similar to webview. Alongside this effort, the group began implementing an OpenLayers fire map using a simpler UI. This web app was completed fairly quickly relative to Google Maps; however, it did not include functionality such as satellite imagery or searchable locations. The group finished the project with a working android version of the Google Maps based app supporting API levels 14-19 and an OpenLayers based app supporting API levels 8-19, as well as a Google Maps based IOS app supporting both old and new screen formats. This project was implemented by high school and college students under an SGT Inc. STEM internship program

Synchronizing files or images among several computers or removable devices. A utility to avoid frequent back-ups.

PubMed

Leonardi, Rosalia; Maiorana, Francesco; Giordano, Daniela

2008-06-01

Many of us use and maintain files on more than 1 computer--a desktop part of the time, and a notebook, a palmtop, or removable devices at other times. It can be easy to forget which device contains the latest version of a particular file, and time-consuming searches often ensue. One way to solve this problem is to use software that synchronizes the files. This allows users to maintain updated versions of the same file in several locations.

The ChEMBL database as linked open data

PubMed Central

2013-01-01

Background Making data available as Linked Data using Resource Description Framework (RDF) promotes integration with other web resources. RDF documents can natively link to related data, and others can link back using Uniform Resource Identifiers (URIs). RDF makes the data machine-readable and uses extensible vocabularies for additional information, making it easier to scale up inference and data analysis. Results This paper describes recent developments in an ongoing project converting data from the ChEMBL database into RDF triples. Relative to earlier versions, this updated version of ChEMBL-RDF uses recently introduced ontologies, including CHEMINF and CiTO; exposes more information from the database; and is now available as dereferencable, linked data. To demonstrate these new features, we present novel use cases showing further integration with other web resources, including Bio2RDF, Chem2Bio2RDF, and ChemSpider, and showing the use of standard ontologies for querying. Conclusions We have illustrated the advantages of using open standards and ontologies to link the ChEMBL database to other databases. Using those links and the knowledge encoded in standards and ontologies, the ChEMBL-RDF resource creates a foundation for integrated semantic web cheminformatics applications, such as the presented decision support. PMID:23657106

EAU Guidelines on Non-Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016.

PubMed

Babjuk, Marko; Böhle, Andreas; Burger, Maximilian; Capoun, Otakar; Cohen, Daniel; Compérat, Eva M; Hernández, Virginia; Kaasinen, Eero; Palou, Joan; Rouprêt, Morgan; van Rhijn, Bas W G; Shariat, Shahrokh F; Soukup, Viktor; Sylvester, Richard J; Zigeuner, Richard

2017-03-01

The European Association of Urology (EAU) panel on Non-muscle-invasive Bladder Cancer (NMIBC) released an updated version of the guidelines on Non-muscle-invasive Bladder Cancer. To present the 2016 EAU guidelines on NMIBC. A broad and comprehensive scoping exercise covering all areas of the NMIBC guidelines published between April 1, 2014, and May 31, 2015, was performed. Databases covered by the search included Medline, Embase, and the Cochrane Libraries. Previous guidelines were updated, and levels of evidence and grades of recommendation were assigned. Tumours staged as TaT1 or carcinoma in situ (CIS) are grouped as NMIBC. Diagnosis depends on cystoscopy and histologic evaluation of the tissue obtained by transurethral resection of the bladder (TURB) in papillary tumours or by multiple bladder biopsies in CIS. In papillary lesions, a complete TURB is essential for the patient's prognosis. If the initial resection is incomplete, there is no muscle in the specimen, or a high-grade or T1 tumour is detected, a second TURB should be performed within 2-6 wk. The risks of both recurrence and progression may be estimated for individual patients using the European Organisation for Research and Treatment of Cancer (EORTC) scoring system and risk tables. The stratification of patients into low-, intermediate-, and high-risk groups is pivotal to recommending adjuvant treatment. For patients with a low-risk tumour and intermediate-risk patients at a lower risk of recurrence, one immediate instillation of chemotherapy is recommended. Patients with an intermediate-risk tumour should receive 1 yr of full-dose bacillus Calmette-Guérin (BCG) intravesical immunotherapy or instillations of chemotherapy for a maximum of 1 yr. In patients with high-risk tumours, full-dose intravesical BCG for 1-3 yr is indicated. In patients at highest risk of tumour progression, immediate radical cystectomy (RC) should be considered. RC is recommended in BCG-refractory tumours. The long version of the guidelines is available at the EAU Web site (www.uroweb.org/guidelines). These abridged EAU guidelines present updated information on the diagnosis and treatment of NMIBC for incorporation into clinical practice. The European Association of Urology has released updated guidelines on Non-muscle-invasive Bladder Cancer (NMIBC). Stratification of patients into low-, intermediate-, and high-risk groups is essential for decisions about adjuvant intravesical instillations. Risk tables can be used to estimate risks of recurrence and progression. Radical cystectomy should be considered only in case of failure of instillations or in NMIBC with the highest risk of progression. Copyright © 2016. Published by Elsevier B.V.

The validity and reliability of the Persian version of the Revised Fibromyalgia Impact Questionnaire.

PubMed

Ghavidel Parsa, Banafsheh; Amir Maafi, Alireza; Haghdoost, Afrooz; Arabi, Yasaman; Khojamli, Monire; Chatrnour, Gelayol; Bidari, Ali

2014-02-01

The Revised Fibromyalgia Impact Questionnaire (FIQR), an updated version of the Fibromyalgia Impact Questionnaire (FIQ) achieved a better balance among different domains (i.e., function, overall impact, and symptom severity) and attempts to address the limitations of FIQ. As there is no Persian version of the FIQR available, we aimed to investigate the validity and reliability of a Persian translation of the FIQR in Iranian patients. After translating the FIQR into Persian, it was administered to 77 female patients with fibromyalgia syndrome. All of the patients filled out the questionnaire together with a Persian version of the FIQ, short form-12 (SF-12). The tender-point count was also calculated. One week later, FM patients filled out the Persian FIQR at their second visit. Reliability was analyzed by internal consistency and reproducibility including Cronbach's α coefficient and intra-class correlation coefficient. Construct validity was evaluated by Spearman's correlation coefficient and Pearson's correlation coefficient. Statistical analysis was performed using SPSS for Windows version 17.0. All patients included in this study were female, and the mean age was 38.23 ± 10.68 years. The total scores of the FIQR and FIQ were 49.77 ± 18.27 and 54.05 ± 14.00 that were closely correlated (r = 0.63, p < 0.01), and each of the three domains of the Persian FIQR was also correlated well with the three related FIQ domains (r = 0.36-0.63, p < 0.01). Also some significant inverse correlations of FIQR with quality-of-life (assessed by SF-12) domains and items were found. Cronbach's α was 0.87 for FIQR in the first visit. The Persian FIQR showed adequate reliability and validity. This instrument can be used in the clinical evaluation of Iranian patients with fibromyalgia.

Communication Services and Supports for Individuals with Severe Disabilities: Guidance for Assessment and Intervention

PubMed Central

Brady, Nancy C.; Bruce, Susan; Goldman, Amy; Erickson, Karen; Mineo, Beth; Ogletree, Bill T.; Paul, Diane; Romski, Mary Ann; Sevcik, Rose; Siegel, Ellin; Schoonover, Judith; Snell, Marti; Sylvester, Lorraine; Wilkinson, Krista

2015-01-01

The National Joint Committee for the Communication Needs of People with Severe Disabilities (NJC) reviewed literature regarding practices for people with severe disabilities in order to update guidance provided in documents originally published in 1992. Changes in laws, definitions, and policies that affect communication attainments by persons with severe disabilities are presented, along with guidance regarding assessment and intervention practices. A revised version of the Communication Bill of Rights, a powerful document that describes the communication rights of all individuals, including those with severe disabilities is included in this article. The information contained within this article is intended to be used by professionals, family members, and individuals with severe disabilities to inform and advocate for effective communication services and opportunities. PMID:26914467

An event-version-based spatio-temporal modeling approach and its application in the cadastral management

NASA Astrophysics Data System (ADS)

Li, Yangdong; Han, Zhen; Liao, Zhongping

2009-10-01

Spatiality, temporality, legality, accuracy and continuality are characteristic of cadastral information, and the cadastral management demands that the cadastral data should be accurate, integrated and updated timely. It's a good idea to build an effective GIS management system to manage the cadastral data which are characterized by spatiality and temporality. Because no sound spatio-temporal data models have been adopted, however, the spatio-temporal characteristics of cadastral data are not well expressed in the existing cadastral management systems. An event-version-based spatio-temporal modeling approach is first proposed from the angle of event and version. Then with the help of it, an event-version-based spatio-temporal cadastral data model is built to represent spatio-temporal cadastral data. At last, the previous model is used in the design and implementation of a spatio-temporal cadastral management system. The result of the application of the system shows that the event-version-based spatio-temporal data model is very suitable for the representation and organization of cadastral data.

An integrated approach to conjunctive-use analysis with the one-water hydrologic flow model, MODFLOW-OWHM

USGS Publications Warehouse

Boyce, Scott E.; Hanson, Randall T.

2015-01-01

The MODFLOW-2005 (MF) family of hydrologic simulators has diverged into multiple versions designed for specific needs, thus limiting their use to their respective designs. The One-Water Hydrologic Flow Model (MF-OWHM v1.0) is an integrated hydrologic flow model that is an enhanced fusion of multiple MF versions. While maintaining compatibility with existing MF versions, MF-OWHM includes: linkages for coupled heads, flows, and deformation; facilitation of self-updating models, additional observation and parameter options for higher-order calibrations; and redesigned code for faster simulations. This first release of MF-OWHM incorporates MODFLOW-2005 and the Farm Process (MF-FMP2), with new features (FMP3), combined with Local Grid Refinement (MF-LGR), Streamflow Routing (SFR), Surfacewater Routing Process (SWR), Seawater Intrusion (SWI), Riparian Evapotranspiration (RIP-ET), the Newton Formulation (MF-NWT), and more. MF-OWHM represents a complete integrated hydrologic model that fully links the movement and use of groundwater, surface water, and imported water for consumption by agriculture and natural vegetation on the landscape, and for potable and other uses. By retaining and keeping track of the water during simulation of the hydrosphere, MF-OWHM accounts for “all of the water everywhere and all of the time.” This provides the foundation needed to address integrated hydrologic problems such as evaluation of conjunctive-use alternatives and sustainability analysis, including potential adaptation and mitigation strategies, and best management practices.

2004 GUIDELINES FOR WATER REUSE

EPA Science Inventory

The Guidelines for Water Reuse is an update of a similar document developed jointly by EPA and Camp, Dresser & McKee, Inc. in 1992. As with the earlier version, a committee of national and international experts in the field of water reclamation was established to draft new text a...