1986-08-01
SECURITY CLASSIFICATION AUTHORITY 3 DISTRIBUTIONAVAILABILITY OF REPORT N/A \\pproved for public release, 21b. OECLASS FI) CAT ) ON/OOWNGRAOING SCMEOLLE...from this set of projections. The Convolution Back-Projection (CBP) algorithm is widely used technique in Computer Aide Tomography ( CAT ). In this work...University of Illinois at Urbana-Champaign. 1985 Ac % DTICEl_ FCTE " AUG 1 11986 Urbana. Illinois U,) I A NEW METHOD OF SYNTHETIC APERTURE RADAR IMAGE
1992-11-01
Subharmonic Forced Traveling Waves in a Thin Perfect Circular Disk T. A. Nayfeh and A. F. Vakakis, University of Illinois at Urbana -Champaign, Urbana ...of Illinois at Urbana -Champaign, Urbana , IL and J. Awrejcewicz, The University of Tokyo, Tokyo, JAPAN 0830-1010 On the Nonlinear Parametric Excitation...and A. F. Vakakis, University of Illinois at Urbana -Champaign, Urbana , IL Thursday, June 11 Session 15. Multibody Dynamics I/ Chairmen: G. Anderson
Adaptive Incentive Controls for Stackelberg Games with Unknown Cost Functionals.
1984-01-01
APR EZT:: F I AN 73S e OsL:-: UNCLASSI?:-- Q4~.’~- .A.., 6, *~*i i~~*~~*.- U ADAPTIVE INCENTIVE CONTROLS FOR STACKELBERG GAMES WITH UNKNOWN COST...AD-A161 885 ADAPTIVE INCENTIVE CONTROLS FOR STACKELBERG GAMES WITH i/1 UNKNOWN COST FUNCTIONALSCU) ILLINOIS UNIV AT URBANA DECISION AND CONTROL LAB T...ORGANIZATION 6b. OFFICE SYMBOL 7.. NAME OF MONITORING ORGANIZATION CoriaeLcenef~pda~ Joint Services Electronics Program Laboratory, Univ. of Illinois N/A
An Assessment of Previous Archaeological Surveys at Fort Campbell, Kentucky/Tennessee
2006-04-01
Krejsa Public Service Archaeology Program Department of Anthropology University of Illinois Urbana , IL 61801 Michael L. Hargrave Construction...ii Abstract: From September 2003 through June 2004 the Public Service Archaeology Program (PSAP) of the University of Illinois at Urbana ...of this work was done by Dr. Paul Krejsa, Public Service Archaeological Program, University of Illinois at Urbana - Champaign, under contract DACA42-00
1982-03-01
Illinois Historical Survey Library ( Urbana ). Very little documentary material pertinent to the project area was found. The Scripps’ (1891) manuscript...within the project area. Illinois Archaeological Survey ( Urbana ). The IAS maintains the active site files for archaeological sites within the state of...should include consulting these site files. University of Illinois ( Urbana ). The most interest- ing documentary materials here were the Smithsonian Insti
Early Detection of Ovarian Cancer by Contrast-Enhanced Ultrasound-Targeted Imaging
2013-09-01
and Pam Utterback and Doug Hilgendorf, staff of the University of Illinois at 400 Urbana-Champaign Poultry Research Farm , for maintenance of the hens...Utterback and Doug Hilgendorf, staff of the University of Illinois at Urbana-Champaign Poultry Re- search Farm , for maintenance of the hens. The authors also...and Doug Hilgendorf, staff of the University of Illinois at Urbana- Champaign Poultry Research Farm , for maintenance of the hens. They also thank
Home school student visit and introduction to rail transportation and engineering.
DOT National Transportation Integrated Search
2016-06-22
This project consisted of hosting local Champaign-Urbana, Illinois home school students for a visit to : the Rail Transportation and Engineering Center (RailTEC) at the University of Illinois at Urbana- : Champaign (UIUC). Beyond visiting RailTEC, st...
Regis, Manuela Ferreira; Oliveira, Luciano Machado Ferreira Tenório de; Santos, Ana Raquel Mendes Dos; Leonidio, Ameliane da Conceição Reubens; Diniz, Paula Rejane Beserra; Freitas, Clara Maria Silvestre Monteiro de
2016-01-01
To analyze the levels of physical activity and sedentary behavior in adolescents living in urban and rural areas. An epidemiological, cross-section study with quantitative design, carried out at the regional level. The sample comprised 6,234 students aged 14 to 19 years, selected using random cluster sampling. The χ2 test and binary logistic regression were used in the analysis. A total of 74.5% of adolescents lived in urban areas. After adjustment, rural residents spent less time watching television (odds ratio - OR: 0.45; 95% confidence interval - 95%CI: 0.39-0.52), using a computer and/or playing video games (OR: 0.30; 95%CI: 0.22-0.42), or sitting down (OR: 0.66; 95%CI: 0.54-0.80); chose passive leisure less often (OR: 0.83; 95%IC: 0.72-0.95) and were less likely to be classified as insufficiently active (OR: 0.88; 95%IC: 0.78-0.99) when compared to urban residents, regardless of sex or age. The fact that adolescents living in rural areas who did not work were more likely to be classified as insufficiently active (OR: 2.59; 95%CI: 2.07-3.24) emphasized the significant role of occupation in physical activity levels in this group. Adolescents living in rural areas were less exposed to the sedentary behaviors, chose more active leisure, and had higher levels of physical activity. Place of residence and occupation may play a major role in youth lifestyle. Analisar os níveis de atividade física e o comportamento sedentário em adolescentes das áreas urbanas e rurais. Estudo epidemiológico, transversal, com abordagem quantitativa e abrangência estadual, cuja amostra foi constituída por 6.234 estudantes (14 a 19 anos), selecionados por meio de uma estratégia de amostragem aleatória de conglomerados. As análises foram realizadas por meio do teste χ2 e da regressão logística binária. Na amostra, 74,5% dos adolescentes eram residentes em área urbana. Após o ajuste, constatou-se que os adolescentes oriundos da área rural usavam menos televisão (odds ratio - OR: 0,45; intervalo de confiança de 95% - IC95%: 0,39-0,52), computador e/ou videogame (OR: 0,30; IC95%: 0,22-0,42), passavam menos tempo sentados (OR: 0,66; IC95%: 0,54-0,80), optaram menos pelo lazer passivo (OR: 0,83; IC95%: 0,72-0,95) e tinham menos chances de serem classificados como insuficientes ativos (OR: 0,88; IC95%: 0,78-0,99), quando comparados àqueles que residiam na área urbana, independentemente do sexo e da idade. Os adolescentes da área rural que não trabalhavam apresentaram mais chances de serem classificados como insuficientemente ativos (OR: 2,59; IC95%: 2,07-3,24), mostrando que a ocupação tinha um papel importante no nível de atividade física deste grupo. Os adolescentes residentes na área rural estiveram menos expostos aos comportamentos sedentários, optaram mais por um lazer ativo e apresentaram um melhor nível de atividade física, podendo a zona de domicílio e a ocupação influenciar no estilo de vida deles.
Surface Wave Attenuation in the Tibetan Plateau from Ambient Noise
2015-08-31
Urbana-Champaign Department of Geology 605 E. Springfield Ave. Champaign, IL 61820 31 August 2015 Final Report APPROVED FOR PUBLIC RELEASE...ADDRESS(ES) University of Illinois at Urbana-Champaign 1Los Alamos National Laboratory Department of Geology PO Box 1663 605 E
Environmental Biology Programs at the University of Illinois, Urbana-Champaign.
ERIC Educational Resources Information Center
Getz, Lowell L.
1987-01-01
Describes the programs of the Department of Ecology, Ethology, and Evolution at the University of Illinois (Urbana-Champaign). Focuses on the graduate degrees offered in environmental biology. Lists research interests and courses in plant biology, entomology, forestry, civil engineering, and landscape architecture. (TW)
Group A rotavirus gastroenteritis: post-vaccine era, genotypes and zoonotic transmission.
Luchs, Adriana; Timenetsky, Maria do Carmo Sampaio Tavares
2016-01-01
ABSTRACTThis article provides a review of immunity, diagnosis, and clinical aspects of rotavirus disease. It also informs about the changes in epidemiology of diarrheal disease and genetic diversity of circulating group A rotavirus strains following the introduction of vaccines. Group A rotavirus is the major pathogen causing gastroenteritis in animals. Its segmented RNA genome can lead to the emergence of new or unusual strains in human populations via interspecies transmission and/or reassortment events.RESUMOEste artigo fornece uma revisão sobre imunidade, diagnóstico e aspectos clínicos da doença causada por rotavírus. Também aponta as principais mudanças no perfil epidemiológico da doença diarreica e na diversidade genética das cepas circulantes de rotavírus do grupo A, após a introdução vacinal. O rotavírus do grupo A é o principal patógeno associado à gastroenterite em animais. Seu genoma RNA segmentado pode levar ao surgimento de cepas novas ou incomuns na população humana, por meio de transmissão entre espécies e eventos de rearranjo.
Properties of a Purified Halophilic Malic Dehydrogenase
Holmes, P. K.; Halvorson, H. Orin
1965-01-01
Holmes, P. K. (University of Illinois, Urbana), and H. Orin Halvorson. Properties of a purified halophilic malic dehydrogenase. J. Bacteriol. 90:316–326. 1965.—The malic dehydrogenase (MDH) from Halobacterium salinarium required high concentrations of monovalent ions for stability and activity. Studies of inactivation rates at different salt concentrations suggested that approximately 25% NaCl (w/v) is required to stabilize MDH. From 50 to 100% reactivation, depending on the salt concentration present during inactivation, could occur in 2.5 to 5 m NaCl or KCl. The optimal salt concentration for activity of MDH was a function of the pH, and ranged from 1 to 3 m NaCl or KCl. The effect of salt concentration on the pH-activity curves occurred chiefly below pH 7.0. Inactivation of MDH with heat or thiol reagents showed that the enzyme was more labile in the state induced by absence of salt. The activation of MDH by salts was attributed to a decreased rate of dissociation of MDH and reduced nicotinamide adenine dinucleotide (NADH2). The inactivation of the enzyme in the absence of salt could be largely prevented by the presence of NADH2. The S20.w of MDH decreased threefold at low salt concentrations. The enzyme was assumed to be in its native compact configuration only in the presence of a high concentration of salt. PMID:14329442
Content Area Reading: A Functional Approach.
ERIC Educational Resources Information Center
Plecki, Gerard D.
The implementation of a content reading program at Urbana High School, Urbana, Illinois, is discussed in this document. Reading staff hired with Title VII funds offered assistance to all teachers in the high school by working with classroom teachers in their classes for 60 minutes of class time per week. Free reading time devoted to high-interest…
Building Preservation: The University of Illinois at Urbana-Champaign's Stacks Assessment.
ERIC Educational Resources Information Center
Teper, Thomas H.; Atkins, Stephanie S.
2003-01-01
Discusses the results of two collection assessments conducted 13 years apart at the University of Illinois at Urbana-Champaign. Both assessments focused on the central stacks collection, a repository collection serving the institution's 42 branch and departmental libraries. Findings provide insight into the results of deferred collections care and…
The English Placement Test at the University of Illinois at Urbana-Champaign
ERIC Educational Resources Information Center
Chung, Sun Joo; Haider, Iftikhar; Boyd, Ryan
2015-01-01
At the University of Illinois at Urbana-Champaign (UIUC), the English Placement Test (EPT) is the institutional placement test that is used to place students into appropriate English as a second language (ESL) writing and/or pronunciation service courses. The EPT is used to assess the English ability of newly admitted international undergraduate…
Design and Demonstration of RSFQ Processor Datapath for High Performance Computing
2014-09-30
Date(f-2): 1 b. InQubit, Inc. 21143 Hawthorne Blvd. #459 Torrance CA 90503 SF Memory Development University oF Illinois-Urbana Champagne 00000 University...oF Illinois-Urbana Champagne 00000 1 a. 1 a. 1 a. Inventions (DD882) Scientific Progress See Attachment Technology Transfer N Patent Filed in US? (5d
ERIC Educational Resources Information Center
Sadayuki, Taisuke
2015-01-01
This paper empirically investigates the costs that arise from uncertainty in the college-town housing market in the Urbana-Champaign metropolitan area, the home of the University of Illinois. This research resulted in two principal findings. First, the rental price of housing owned by property owners having more than 10 claims filed against them…
Backlash over Enrollment Proposal at U. of Illinois Leads to Quick Retraction
ERIC Educational Resources Information Center
Kean, Sam
2006-01-01
The University of Illinois at Urbana-Champaign decided last spring to increase its enrollment of non-Illinois students, noting that the Urbana-Champaign campus has the lowest proportion of out-of-state students among the Big Ten universities, with 11 percent. Out-of-state applicants have ACT scores up to a point and a half higher than in-state…
Nonlinear Analysis of Mechanical Systems Under Combined Harmonic and Stochastic Excitation
1993-05-27
Namachchivaya and Naresh Malhotra Department of Aeronautical and Astronautical Engineering University of Illinois, Urbana-Champaign Urbana, Illinois...Aeronauticai and Astronautical Engineering, University of Illinois, 1991. 2. N. Sri Namachchivaya and N. Malhotra , Parametrically Excited Hopf Bifurcation...Namachchivaya and N. Malhotra , Parametrically Excited Hopf Bifurcation with Non-semisimple 1:1 Resonance, Nonlinear Vibrations, ASME-AMD, Vol. 114, 1992. 3
ERIC Educational Resources Information Center
Heiser, Linda M.; Abbed, Nejla
In 1989, a two-year study was completed comparing the academic progress of community college transfers, senior college transfers, and continuing juniors (natives) at the University of Illinois at Urbana-Champaign (UIUC). The study samples were comprised of 673 former community college students and 393 senior college transfers who entered UIUC in…
The Classification, Detection and Handling of Imperfect Theory Problems.
1987-04-20
Explanation-Based Learning: Failure-Driven Schema Refinement." Proceedings of the Third IEEE Conference on Artificial Intelligence Applications . Orlando...A. Rajamoney. Gerald F. DeJong Artificial Intelligence Research Group " . Coordinated Science Laboratory " University of Illinois at Urbana-Champaign...Urbana. IL 61801 . April 1987 ABSTRACT This paper also appears in the Proceedings of the Tenth International Conference on Artificial Intelligence
ERIC Educational Resources Information Center
Ferber, Marianne; Loeb, Jane
This report presents information on the employment status of women at the Urbana-Champaign campus of the University of Illinois. Discussed are: (1) the representation, rank, and pay of females on the faculty; (2) representation of women in administrative positions; (3) representation of women on the faculty versus representation in the labor…
Cryogenic Frequency Domain Optical Mass Memory.
1982-12-10
Schuster Dr. William M. Jackson Chemistry Department Department of Chemistry University of Illinois Howard University Urbana, Illinois 61801 Washington...DC 20059 Dr. A. Adamson Dr. George E. Walraffen Department of Chemistry Department of Chemistry University of Southern Howard University California...University of Illinois Howard University Urbana, Illinois 61801 1 Washixgton, DC 20059 Dr. A. Adamson Dr. George E. Walraffen Department of Chemistry
US-Europe Workshop on Impact of Multifunctionality on Damage Evolution in Composite Materials
2015-09-01
Inventions (DD882) Scientific Progress See Attachment Technology Transfer Not applicable UNIVERSITY OF ILLINOIS AEROSPACE ENGINEERING...Composite Materials PI: Ioannis Chasiotis Aerospace Engineering University of Illinois at Urbana-Champaign Talbot Lab, 104 S. Wright Street, Urbana, IL...focused on the current state of corporate research in the aerospace industry which is a major potential adopter of multifunctional composites. The two
ERIC Educational Resources Information Center
Konopasek, Katherine; O'Brien, Nancy Patricia
A survey was conducted from mid-January to mid-April 1980 in order to evaluate patterns of use for individual titles within the periodical section of the Undergraduate Library (UGL) of the University of Illinois at Urbana-Champaign. Bound volume usage was measured by affixing self-adhesive markers to volume spines when reshelving, and later…
ERIC Educational Resources Information Center
Sng, Dennis Cheng-Hong
The University of Illinois at Urbana-Champaign (UIUC) has a large campus computer network serving a community of about 20,000 users. With such a large network, it is inevitable that there are a wide variety of technologies co-existing in a multi-vendor environment. Effective network monitoring tools can help monitor traffic and link usage, as well…
ERIC Educational Resources Information Center
Stumpff, Julia C.
2003-01-01
College health center personnel are no different from other health practitioners in their need for medical information. To help meet this need, the McKinley Health Center, University of Illinois Urbana-Champaign, developed a partnership in 1997 with the Library of the Health Sciences-Urbana, a regional site library of the University of Illinois at…
Men's health: non-communicable chronic diseases and social vulnerability.
Bidinotto, Daniele Natália Pacharone Bertolini; Simonetti, Janete Pessuto; Bocchi, Silvia Cristina Mangini
2016-08-15
to evaluate the relationship between absences in scheduled appointments and the number of non-communicable chronic diseases and to investigate the relationship between spatial distribution of these diseases and social vulnerability, using geoprocessing. a quantitative study of sequential mixed approach by analyzing 158 medical records of male users to relate the absences and 1250 medical records for geoprocessing. the higher the number of absences in the scheduled medical appointments, the less were the number of non-communicable chronic diseases and the ones listed in the International Classification of Diseases in single men. There were 21 significant geostatistically cases of glucose intolerance in the urban area. Of these, 62% lived in a region with a social vulnerability rating of Very Low, Medium 19%, 14% Low and 5% High. it was observed that the older the men, the greater is the number of chronic diseases and the less they miss scheduled appointments. Regarding the use of geoprocessing, we obtained a significant number of cases of glucose intolerance in urban areas, the majority classified as Very Low social vulnerability. It was possible to relate the spatial distribution of these diseases with the social vulnerability classification; however, it was not possible to perceive a relationship of them with the higher rates of social vulnerability. avaliar a relação entre as faltas em consultas agendadas e o número de doenças crônicas não transmissíveis e averiguar a relação entre distribuição espacial dessas doenças e vulnerabilidade social, utilizando-se o geoprocessamento. estudo quantitativo, de abordagem mista sequencial, sendo analisados 158 prontuários de usuários do sexo masculino para se relacionar as faltas e 1250 prontuários para o geoprocessamento. quanto maior o número de faltas nas consultas médicas agendadas, menores foram a quantidade de doenças crônicas não transmissíveis e as listadas na Classificação Internacional de Doenças em homens solteiros. Obtiveram-se 21 casos geoestatisticamente significantes de intolerância à glicose na zona urbana. Desses, 62% moravam em região com a classificação de vulnerabilidade social Muito Baixa, 19% Média, 14% Baixa e 5% Alta. observou-se que quanto mais velhos os homens, maior é o número de doenças crônicas instaladas e menos eles faltam em consultas agendadas. Quanto ao uso do geoprocessamento, obteve-se número de casos significantes de intolerância à glicose na zona urbana, sendo a maioria classificada como vulnerabilidade social Muito Baixa. Pôde-se relacionar a distribuição espacial dessas doenças com a classificação de vulnerabilidade social, porém, não foi possível perceber uma relação delas com índices mais elevados de vulnerabilidade social. evaluar la relación entre las faltas en las citas programadas y el número de enfermedades crónicas y para investigar la relación entre la distribución espacial de estas enfermedades y la vulnerabilidad social, utilizando geoprocesamiento. estudio cuantitativo de enfoque mixto secuencial y siendo analizadas 158 historias clínicas de los usuarios masculinos para relacionar las faltas y 1250 registros de geoprocesamiento. cuanto mayor eran el número de ausencias en las citas médicas programadas, menores fueron el número, para los hombres solteiros, de enfermedades crónicas y de las incluídas en la Clasificación Internacional de Enfermedades. Se obtuvieron 21 casos de intolerancia a la glucosa geoestadísticamente significativos en el área urbana. De éstos, el 62% viven en una región con calificación de vulnerabilidad social muy baja 19%, media, 14% baja y 5% Alta. se observó que cuanta mayor la edad de los hombres, mayor es el número de enfermedades crónicas instaladas y menos faltas en las citas programadas. Respecto al uso de geoprocesamiento, obtuvimos número significativo de casos de intolerancia a la glucosa en las zonas urbanas, la mayoría clasificada como vulnerabilidad social Muy baja. Se podría relacionarse la distribución espacial de estas enfermedades con la clasificación de la vulnerabilidad social, sin embargo, no fue posible ver una relación de esto con mayores tasas de vulnerabilidad social.
2014-03-01
Pincas; Rush University Medical Center, Pathology, Obstetrics and Gynecology Basu, Sanjib; Rush University Medical Center, Preventive Medicine ...and Jacques S Abramowicz 2, 5 Departments of 1 Pharmacology, 2 Obstetrics and Gynecology, 3 Pathology, 5 Preventive Medicine (Biostatistics...Animal Sciences, University of Illinois at Urbana-Champaign, Urbana (Dr Bahr Obstetrics and Gynecology, Wayne State University School of Medicine
Understanding and Representing Natural Language Meaning.
1982-12-01
agent- controller ) (e.g. John hit Mary.) --subject of transitive ( non -agent) (e.g. John received a telegram.) -object-complement (e.g. They elected...UNIT NUMUERS Coordinated Science Laboratory University of Illinois at Urbana-Champaign Urbana, IL 61801 I1. CONTROLLING OFFICE NAME AND ADDRESS 12...REPORT DATE Office of Naval Research DECEMBER 1982 800 N. Quincy Street is. NUMBER OF PAQES Arlington, VA 22217 44 14. MONITORING AGENCY NAME & AODRESS
Observations of the upper troposphere and lower stratosphere using the urbana coherent-scatter radar
NASA Technical Reports Server (NTRS)
Goss, L. D.; Bowhill, S. A.
1983-01-01
The Urbana coherent-scatter radar was used to observe the upper troposphere and lower stratosphere, and 134 hours of data were collected. Horizontal wind measurements show good agreement with balloon-measured winds. Gravity waves were frequently observed, and were enhanced during convective activity. Updrafts and downdrafts were observed within thunderstorms. Power returns are related to hydrostatic stability, and changes in echo specularity are shown.
Incorporating Temporal Information in Microblog Retrieval
2012-11-01
Urbana-Champaign Urbana-Champaign, IL, USA willis8@illinois.edu Richard Medlin School of Information & Library Science University of North Carolina at...Chapel Hill Chapel Hill, NC, USA rich_medlin@med.unc.edu Jaime Arguello † School of Information & Library Science University of North Carolina at...published prior to time tQ. The School of Information and Library Science at the Uni- versity of Carolina at Chapel Hill submitted four runs to the Microblog
2006-11-01
Avenue Urbana , IL 61801-4797 Final report Approved for public release; distribution is unlimited. Prepared for U.S. Army Corps of Engineers...allow validation of each structure’s effectiveness. Approach A research team consisting of members from the University of Illinois, Urbana ...and preferential drainage channel. Furthermore, dry weather conditions on unimproved ERDC/CERL TR-06-31 4 roads generate large volumes of airborne
Effect of Woody Vegetation on Hydraulic Conductivity at Various Levee Systems Using Numerical Models
2012-06-01
XIX International Conference on Water Resources CMWR 2012 University of Illinois at Urbana -Champaign June 17-22, 2012 1 EFFECT OF WOODY...distribution unlimited 13. SUPPLEMENTARY NOTES Presented at the XIX International Conference on Water Resources CMWR 2012, Urbana -Champaign, IL, June...the Pocket and Burlington levees, the lower toe for the Portland levee, and the bottom of the dewatered drainage ditch for the Albuquerque levee
Solar flare ionization in the mesosphere observed by coherent-scatter radar
NASA Technical Reports Server (NTRS)
Parker, J. W.; Bowhill, S. A.
1986-01-01
The coherent-scatter technique, as used with the Urbana radar, is able to measure relative changes in electron density at one altitude during the progress of a solar flare when that altitude contains a statistically steady turbulent layer. This work describes the analysis of Urbana coherent-scatter data from the times of 13 solar flares in the period from 1978 to 1983. Previous methods of measuring electron density changes in the D-region are summarized. Models of X-ray spectra, photoionization rates, and ion-recombination reaction schemes are reviewed. The coherent-scatter technique is briefly described, and a model is developed which relates changes in scattered power to changes in electron density. An analysis technique is developed using X-ray flux data from geostationary satellites and coherent scatter data from the Urbana radar which empirically distinguishes between proposed D-region ion-chemical schemes, and estimates the nonflare ion-pair production rate.
2016-05-23
UNIVERSITY OF TEXAS AT AUSTIN Final Report 05/23/2016 DISTRIBUTION A: Distribution approved for public release. AF Office Of Scientific Research ...This project led by a team of researchers from the University of Texas at Austin and the University of Illinois, Urbana-Champaign has been engaged in...release. 2 Project Overview: This project led by a team of researchers from the University of Texas at Austin and the University of Illinois, Urbana
Buckler, Denny; Stefanov, Jim
2004-01-01
La region fronteriza de los Estados Unidos y Mexico abarca una gran diversidad de ambientes fisicos y habitaciones, entre los cuales estan los humedales, desiertos, pastos, montanas, y bosques. Estos a su vez son unicos en cuanto a su diversidad de recursos acuaticos minerales, y biologicos. La region se interconecta economica, politica, y socialmente debido a su herencia binacional. En 1995, cerca de 11 millones de habitantes vivian en la zona adyacente a la frontera. Un estudio sugiere que esa poblacion podria doblarse antes del ano 2020.
1993-10-01
Flammia 6, University of Central Florida 7.. . Orlando, Florida 6 UT 2 3 1993 Rebecca 0. Barclay Rensselaer Polytechnic Institute Troy, New York Thomas...of Illinois at Urbana-Champaign Urbana, Illinois John M. Kennedy T--:* i,-,-- -- n e Indiana University ! •o,,-o Cod sae itse!i di t-!1_-,_:’,1 • ; s ...Communication: American-Russian Collaboration Madelyn Flammia English Department Rebecca 0. Barclay University of Central Florida Thomas E. Pinelli
1998-01-01
Matagne1, Jean -Pierre Leburton1 Jacques Destine2, Guy Cantraine2 1Beckman Institute, University of Illinois at Urbana-Champaign , Urbana, IL 61820...PROCESSES R. Peter Smith, Suzanne C. Martin, Moonil Kim, Jean Bruston, Imran Mehdi, Dexter Humphrey, Michael Gaidis, Neal Erickson*, and Peter H...SEV/VSE, Feb. 1981 G. Galup-Montoro, M. Schneider, S. Acosta, R. Pinto , Proc. Brazilian Microelectronics Conference SBMICRO,1996. A. Cunha, O
ERIC Educational Resources Information Center
Abouserie, Hossam Eldin Mohamed Refaat
2007-01-01
The purpose of this study was to explore and investigate the ways faculty at the Graduate School of Library and Information Science at the University of Illinois at Urbana-Champaign use Networked Information Sources And Services to support their research task. Library and Information Sciences faculty at the University of Illinois were chosen as…
ERIC Educational Resources Information Center
Abouserie, Hossam Eldin Mohamed Refaat
2007-01-01
The purpose of this study was to explore and investigate the ways faculty at the Graduate School of Library and Information Science at the University of Illinois at Urbana-Champaign use Networked Information Sources and Services to support their research task. Library and Information Sciences faculty at the University of Illinois were chosen as…
Survey of Urban Meteorological Data.
1984-01-01
8217) 51 • TN Totawe Wayne Airort 4 r l ,4 35 74 14 ,4 I’% .. 14e taI 40 3,5S 14 Ic V- Memoria ! q-hool 40 40 I ’ 1 4 1 0( WF West End 40 46 175 1...Circulation Number of operations: 5--clear light winds 38 W. P. Lowry, 1973, Operational Report for Metromex," Illinois State Water Survey, Urbana , IL...39W. P. Lowry, 1973, Operational Report for Metromnx," Illinois State Water Survey, Urbana , IL T. J. Henderson and 0. W. Duckering, 1976
Secondary metabolites produced by Sardiniella urbana, a new emerging pathogen on European hackberry.
Cimmino, Alessio; Maddau, Lucia; Masi, Marco; Linaldeddu, Benedetto Teodoro; Evidente, Antonio
2018-05-30
In this study the production of secondary metabolites by a virulent strain of Sardiniella urbana, a recently described pathogen originally found on declining European hackberry trees in Italy, was investigated for the first time. Chemical analysis of the culture filtrate extracts led to the isolation of three well known compounds as R-(-)-mellein and (3R,4R)-and (3R,4S)-4-hydroxy melleins which were identified by spectroscopic methods (essentially NMR and ESIMS). The isolated compounds were tested for their phytotoxic, antifungal and zootoxic activities. Among them, only R-(-)-mellein was found to be active.
Aeronomy report no. 74: The Urbana meteor-radar system; design, development, and first observations
NASA Technical Reports Server (NTRS)
Hess, G. C.; Geller, M. A.
1976-01-01
The design, development, and first observations of a high power meteor-radar system located near Urbana, Illinois are described. The roughly five-fold increase in usable echo rate compared to other facilities, along with automated digital data processing and interferometry measurement of echo arrival angles, permits unsurpassed observations of tidal structure and shorter period waves. Such observations are discussed. The technique of using echo decay rates to infer density and scale height and the method of inferring wind shear from radial acceleration are examined. An original experiment to test a theory of the Delta-region winter anomaly is presented.
NASA Astrophysics Data System (ADS)
2014-09-01
Tami Bond, environmental engineer and professor in the Department of Civil and Environmental Engineering at the University of Illinois at Urbana-Champaign, has been selected as a 2014 MacArthur Fellow.
NASA Technical Reports Server (NTRS)
Edwards, B. (Editor)
1981-01-01
Progress in aeronomic research is reported. The following topics are discussed: ionospheric theory; rocket experiments; system development for Urbana measurements; meteor radar; coherent and incoherent scatter radar; and laser radar.
Vulnerability to the transmission of human visceral leishmaniasis in a Brazilian urban area.
Toledo, Celina Roma Sánchez de; Almeida, Andréa Sobral de; Chaves, Sergio Augusto de Miranda; Sabroza, Paulo Chagastelles; Toledo, Luciano Medeiros; Caldas, Jefferson Pereira
2017-05-15
To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We have carried out an analysis of the sociodemographic and urban infrastructure situation of the municipality. Normalized primary indicators were calculated and used to construct the indicators of vulnerability of the social structure, household structure, and urban infrastructure. From them, we have composed a vulnerability index. Kernel density estimation was used to evaluate the density of cases of human visceral leishmaniasis, based on the coordinates of the cases. Bivariate global Moran's I was used to verify the existence of spatial autocorrelation between the incidence of human visceral leishmaniasis and the indicators and index of vulnerability. Bivariate local Moran's I was used to identify spatial clusters. We have observed a pattern of centrifugal spread of human visceral leishmaniasis in the municipality, where outbreaks of the disease have progressively reached central and peri-urban areas. There has been no correlation between higher incidences of human visceral leishmaniasis and worse living conditions. Statistically significant clusters have been observed between the incidences of human visceral leishmaniasis in both periods analyzed (2007 to 2009 and 2010 to 2012) and the indicators and index of vulnerability. The environment in circumscribed areas helps as protection factor or increases the local vulnerability to the occurrence of human visceral leishmaniasis. The use of methodology that analyzes the conditions of life of the population and the spatial distribution of human visceral leishmaniasis is essential to identify the most vulnerable areas to the spread/maintenance of the disease. Analisar determinantes para a ocorrência da leishmaniose visceral humana vinculados às condições de vulnerabilidade. Estudo ecológico, cuja unidade de análise espacial foi a Unidade de Análise Territorial em Araguaína, TO, de 2007 a 2012. Foi realizada análise da situação sociodemográfica e de infraestrutura urbana no município. Indicadores primários normalizados foram calculados e utilizados na construção de indicadores de vulnerabilidade de estrutura social, de estrutura domiciliar e de infraestrutura urbana. A partir deles, foi composto um índice de vulnerabilidade. A estimativa de Kernel foi utilizada para avaliar a densidade de casos de leishmaniose visceral humana, com base nas coordenadas dos casos. O I-Moran Global Bivariado foi empregado para verificar a existência de autocorrelação espacial entre a incidência de leishmaniose visceral humana e os indicadores e índice de vulnerabilidade. I-Moran Local Bivariado foi utilizado para identificar clusters espaciais. Foi observado um padrão de disseminação centrífuga da leishmaniose visceral humana no município, em que surtos da doença atingiram progressivamente áreas centrais e periurbanas. Houve correlação entre maiores incidências de leishmaniose visceral humana e piores condições de vida. Foram observados clusters estatisticamente significativos entre as incidências de leishmaniose visceral humana nos dois períodos analisados (2007 a 2009 e 2010 a 2012) e os indicadores e índice de vulnerabilidade. O ambiente em áreas circunscritas contribui como fator de proteção ou aumenta a vulnerabilidade local à ocorrência de leishmaniose visceral humana. O uso de metodologia que analisa as condições de vida da população e distribuição espacial da leishmaniose visceral humana é essencial na identificação de áreas mais vulneráveis à disseminação/manutenção da doença.
... 1222 immediately. Name State American Association of Poison Control Centers Address AAPCC Central Office NOT A POISON ... not for emergency use. Arkansas ASPCA Animal Poison Control Center Address 1717 S. Philo Road, Suite 36 Urbana, ...
Style of Life and Student Personnel Policy in College Residence Halls
ERIC Educational Resources Information Center
White, Julie E.
1969-01-01
Doctoral dissertation, Dimensions of Conformity and Evasion in Residence Halls for University Women: A Sociological Analysis of Normative Behavior in a Large-Scale Social Organization, 1962, University of Illinois, Urbana.
Atmospheric Science Data Center
2013-04-16
... an immense wintertime pool of pollution over the northern Indian state of Bihar. The discovery was made by researchers analyzing four ... Urbana-Champaign . MISR was built and is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Science Mission ...
Hispanos en la EPA: Grace Robiou
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Hispanos en la EPA: Matthew Tejada
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Hispanos en la EPA: Fabiola Estrada
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Hispanos en la EPA: Joel Corona
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Ice Skating Instruction at the University of Illinois.
ERIC Educational Resources Information Center
Christensen, Char; And Others
1981-01-01
The University of Illinois at Urbana-Champaign conducts a instructional ice skating program for its students and the community. Activities include: a figure skating club; a speed skating club; ice hockey program; and ice skating classes. (CJ)
Investigation of railroad bridge approach problems along heavy haul freight lines.
DOT National Transportation Integrated Search
2015-05-01
Under a contract with the Federal Railroad : Administration (FRA), the University of Illinois at Urbana : Champaign (UIUC) is investigating different factors that : contribute to the problem of differential movement at : railroad track transitions Th...
Ballast degradation characterized through triaxial test : research results.
DOT National Transportation Integrated Search
2016-06-01
Transportation Technology Center, Inc. (TTCI) : has supported the development of a large-scale : triaxial test device (Figure 1) for testing ballast : size aggregate materials at the University of : Illinois at Urbana-Champaign (UIUC). This new : tes...
Railway project design and construction (CEE 411) course updates.
DOT National Transportation Integrated Search
2017-01-20
Course CEE 411 "Railway Project Design and Construction" is a cornerstone of the railway : engineering education program developed by the Rail Transportation and Engineering Center : (RailTEC) at the University of Illinois at Urbana-Champaign (UIUC)....
Hispanos en la EPA: Sally Gutiérrez
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Perfiles de hispanos en la EPA
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente de todos.
Hispanos en la EPA: Nadtya Y. Hong
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Hispanos en la EPA: Evelyn Rivera-Ocasio
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Hispanos en la EPA: Elias Rodríguez
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Sharing her passion with others.
Henze, Tonja Marie
2013-10-22
Tonja Marie Henze, MS, CMAR, RLATg, Facilities Coordinator, Division of Animal Resources, University of Illinois, Urbana, IL. Ms. Henze talks about the joys and challenges of her job and realizing the importance of speaking out about her passion for laboratory animal care.
UIUC concrete tie and fastener field testing at TTC.
DOT National Transportation Integrated Search
2014-07-01
In July 2012, the University of Illinois at Urbana-Champaign (UIUC) began an extensive : experimental program at the Transportation : Technology Center (TTC) in Pueblo, CO. The : field experimentation program was part of a : larger research program f...
Designing Educational Programs for Minority Entrepreneurs.
ERIC Educational Resources Information Center
Pride, Michelle L.; Stoffel, Bruce; van Es, J. C.
1997-01-01
When Urbana (Illinois) city government had difficulty recruiting minority contractors, extension educators interviewed 22 minority entrepreneurs, finding they had difficulty meeting requirements and learning about opportunities. Solutions included training for banking, legal, and insurance representatives; workshops to develop bidding skills; and…
NASA Astrophysics Data System (ADS)
Garcia, M. H.
2016-12-01
Modeling Sediment Transport Using a Lagrangian Particle Tracking Algorithm Coupled with High-Resolution Large Eddy Simulations: a Critical Analysis of Model Limits and Sensitivity Som Dutta1, Paul Fischer2, Marcelo H. Garcia11Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, Urbana, Il, 61801 2Department of Computer Science and Department of MechSE, University of Illinois at Urbana-Champaign, Urbana, Il, 61801 Since the seminal work of Niño and Garcia [1994], one-way coupled Lagrangian particle tracking has been used extensively for modeling sediment transport. Over time, the Lagrangian particle tracking method has been coupled with Eulerian flow simulations, ranging from Reynolds Averaged Navier-Stokes (RANS) based models to Detached Eddy Simulations (DES) [Escauriaza and Sotiropoulos, 2011]. Advent of high performance computing (HPC) platforms and faster algorithms have resulted in the work of Dutta et al. [2016], where Lagrangian particle tracking was coupled with high-resolution Large Eddy Simulations (LES) to model the complex and highly non-linear phenomenon of Bulle-Effect at diversions. Despite all the advancements in using Lagrangian particle tracking, there has not been a study that looks in detail at the limits of the model in the context of sediment transport, and also analyzes the sensitivity of the various force formulation in the force balance equation of the particles. Niño and Garcia [1994] did a similar analysis, but the vertical flow velocity distribution was modeled as the log-law. The current study extends the analysis by modeling the flow using high-resolution LES at a Reynolds number comparable to experiments of Niño et al. [1994]. Dutta et al., (2016), Large Eddy Simulation (LES) of flow and bedload transport at an idealized 90-degree diversion: insight into Bulle-Effect, River Flow 2016 - Constantinescu, Garcia & Hanes (Eds), Taylor & Francis Group, London, 101-109. Escauriaza and Sotiropoulos, (2011), Lagrangian model of bed-load transport in turbulent junction flows, Journal of Fluid Mechanics, 666,36-76. Niño and García, (1994), Gravel saltation: 2. Modeling, Water Resources Research, 30(6),1915-1924. Niño et al., (1994), Gravel saltation: 1. Experiments, Water Resources Research, 30(6), 1907-1914.
NASA Astrophysics Data System (ADS)
Zhao, Y.; Taylor, M.; Hagan, M. E.; Pautet, P. D.; Pugmire, J. R.; Pendleton, W. R., Jr.; Russell, J. M., III
2016-12-01
The Andes Lidar Observatory (ALO) is an upper atmospheric observatory located high in the Andes mountain range at Cerro Pachón, Chile (30.3°S, 70.7°W, 2530 m). The Utah State University (USU) Mesospheric Temperature Mapper (MTM) was deployed in August, 2009 collocated with a Na wind/temperature lidar and a meteor wind radar from University of Illinois at Urbana-Champaign (UIUC) as well as other optical instrumentation. In this presentation, we focus on the characteristics of a unique 90-day oscillation identified in the first 18 months in both the mesospheric wind and temperature data from ALO. This event appeared to be long-lived but transient, with similar amplitude to the AO and SAO at this location. Additional mesospheric temperature data from nearby El Leoncito Observatory (31.8°S, 69.3°W), Argentina also showed the same oscillation. The existence and extent of this oscillation are being further examined using SABER/TIMED temperature. The National Center for Atmosphere Research (NCAR) Thermosphere-ionosphere-mesosphere-electrodynamics general circulation model (TIME-GCM) simulation of 2009/10 results are utilized to investigate the possible source of this event and the spatial structures are compared with the results from the SABER temperature data.
Hispanos en la EPA: Neftalí Hernández-Santiago
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Hispanos en la EPA: Rafael DeLeón
La diversidad de la fuerza laboral es importante para la Agencia de Protección Ambiental de EE.UU. (EPA, por sus siglas en inglés). Los empleados hispanos de la EPA contribuyen diariamente hacia la protección de la salud y el medio ambiente.
Stormwater pollution, erosion, and sediment control products demonstration and training center.
DOT National Transportation Integrated Search
2013-04-01
The University of Illinois at Urbana-Champaign (UIUC), the Illinois Department of Transportation (IDOT), and the : Construction Engineering Research Laboratory (CERL) of the U.S. Army Corps of Engineers joined in a : partnership to develop a training...
Development of interdisciplinary undergraduate railroad engineering course.
DOT National Transportation Integrated Search
2016-02-29
Professor James McKinney was a participant in the AREMA 2008 Railroad Engineering Education Symposium (REES) held at the University of Illinois at Urbana-Champaign, as well as the AREMA 2010 REES held at the Johnson County Community College/BNSF's Tr...
Information Resources for Training: A Survey of Non-Military Sources
1975-03-05
Instructional and Research Materials in Vocational at.’’ Technical Education BatteRe Memoria ] Institute Catalog of National Institute of...Reading and Communication Skills National Council of Teachers of English 1111 Kenyon Road Urbana , Illinois 61801 Subject coverage: Areas of reading
Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)
Moose, Steve
2018-02-05
Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.
ERIC Educational Resources Information Center
Nugent, Timothy J.
1978-01-01
The article describes the growth and services of the rehabilitation program at the University of Illinois, Champaign-Urbana, for physically handicapped students. In addition to changing architectural and technological barriers, attitudinal barriers are overcome through pre-admission evaluation, early registration, and various kinds of supportive…
DOT National Transportation Integrated Search
2013-08-01
NURail hosted an REU Summer Program in Multimodal Freight Transportation Risk at the Rail Transportation and Engineering Center (RailTEC) in the Department of Civil and Environmental Engineering at the University of Illinois at Urbana-Champaign (UIUC...
Tackling the Triple-Threat Genome of Miscanthus x giganteus (2010 JGI User Meeting)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moose, Steve
2010-03-25
Steve Moose from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on "Tackling the Triple-Threat Genome of Miscanthus x giganteus" on March 25, 2010 at the 5th Annual DOE JGI User Meeting.
Resilient Localization for Sensor Networks in Outdoor Environments
2004-06-01
Sensor Networks in Outdoor Environments by YoungMin Kwon, Kirill Mechitov, Sameer Sundresh, Wooyoung Kim and Gul Agha June 2004 Report...Environments YoungMin Kwon, Kirill Mechitov, Sameer Sundresh, Wooyoung Kim and Gul Agha Department of Computer Science University of Illinois at Urbana
Two Photon Spectroscopy of UF6 in the Near Ultraviolet
1981-03-10
Chemistry Department Department of Chemistry University of Illinois Howard University Urbana, Illinois 61801 Washington, DC 20059 Dr. A. Adamson Dr. George...E. Walraffer Department of Chemistry Department of Chemistry University of Southern Howard University California Washington, DC 20059 Los Angeles
Grassland ecology and diversity (Ecologia y diversidad de pastizales)
Laurie B. Abbott
2006-01-01
Grasslands of the Chihuahuan Desert region are ecologically and economically important. These grasslands are valued for their rangeland, wildlife, watershed, and recreation resources. Biological diversity also raises the value of grassland communities. The potential for multiple uses within the region increases as the diversity of the resource base increases. In order...
USDA-ARS?s Scientific Manuscript database
Los ácaros constituyen un grupo abundante y diverso que ocupa diferentes hábitats en árboles frutales y la estructura y disposición del follaje y ramas del mango, contribuyen significativamente a que se presente gran diversidad de ácaros benéficos y dañinos asociados a esta especie frutal. En Colomb...
Flores, Yesica Yolanda Rangel
2016-09-01
to analyze the influence of sexual violence on the perception and management of the risk of HIV in women married to migrants. study with an ethnographic approach carried out in urban and rural communities. Data were obtained by methodological triangulation, with participant and non-participant observation, as well as interviews. The informants were 21 women married to international migrants. The interviews were transcribed and discourse analysis was applied to them. three categories emerged from the speeches to problematize the influence of sexual violence in the perception and management of the risk of HIV: "Characterization of sexual practices in the context of migration", "Experiences of sexual violence" and "Construction of the risk of HIV-AIDS". women have difficulty to recognize the acts of sexual violence in their daily lives, and their perceptions of risk are not decisive in the management of the threat to which they are exposed. Therefore, it is becoming increasingly urgent that nursing problematizes the sexual violence within "steady couples", as a challenge to the promotion of healthy lifestyles. analisar a influência que a violência sexual tem na percepção e gestão do risco de HIV em mulheres casadas com migrantes. estudo com enfoque etnográfico, em comunidades urbanas e rurais. Os dados foram obtidos por triangulação metodológica, observação participativa e não participativa, bem como entrevistas. As informantes foram 21 mulheres casadas com migrantes internacionais. As entrevistas foram transcritas e análise de discurso foi aplicada a elas. três categorias emergiram dos discursos, para problematizar a influência da violência sexual na percepção e gestão do risco de HIV: "Caracterização das práticas sexuais no âmbito da migração", "Experiências de violência sexual" e "Construção do risco de HIV-AIDS". as mulheres têm dificuldade para reconhecer os atos de violência sexual em seus cotidianos e as suas percepções de risco não são decisivas na gestão da ameaça a qual estão expostas. Por isso, torna-se urgente que a enfermagem problematize a violência sexual nos "relacionamentos estáveis", como um desafio para a promoção de estilos de vida saudáveis. analizar la influencia que la violencia sexual tiene en la percepción y gestión del riesgo frente al VIH en mujeres parejas de migrantes. estudio con enfoque etnográfico, en comunidades urbanas y rurales. Los datos fueron obtenidos por triangulación de métodos, observación participante y no participante, así como entrevistas. Las informantes fueron 21 mujeres parejas de migrantes internacionales. Las entrevistas se transcribieron y se aplicó sobre ellas análisis de discurso. de los discursos emergieron tres categorías para problematizar la influencia de la violencia sexual en la percepción y la gestión del riesgo frente al VIH: "Caracterización de las prácticas sexuales en el marco de la migración", "Experiencias de violencia sexual" y "Construcción del riesgo de VIH-sida". las mujeres tienen dificultad para reconocer los actos de violencia sexual en sus cotidianeidades y sus percepciones respecto al riesgo no son determinantes en la gestión que respecto a la amenaza asumen. Resulta urgente que enfermería problematice la violencia sexual al interior de las "parejas estables", como desafío en la promoción de estilos de vida saludables.
Clinic, hospital try to fulfill vision of coordinated care with joint venture company.
2000-09-01
Coordinated Care Services Inc., a joint venture of Carle Foundation and Carle Clinic Association in Urbana, IL, shares its initial successes and ongoing challenges after one year of operation. The biggest barrier to further improvements remains insufficient information management capability.
Lepidoptera associated with avocado fruit in Guatemala
USDA-ARS?s Scientific Manuscript database
A total of about 1,098 specimens representing 10 moth species from four families were reared from harvested avocado fruit in Guatemala. Two species were reared from small immature avocados and grown to maturity on unopened avocado flower clusters after small fruit desiccated: (1) Argyrotaenia urbana...
Serials Control System Procedures and Policies.
ERIC Educational Resources Information Center
Schlembach, Mary C.
This document includes procedures and policies for a networked serials control system originally developed at the Grainger Engineering Library Information Center at the University of Illinois at Urbana-Champaign (UIUC). The serials control systems encompass serials processing, public service, and end-user functions. The system employs a…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pitts, Kevin T.
This document is the program for the 6th Annual Midwest Conference for Undergraduate Women in Physics, which was held at the University of Illinois at Urbana-Champaign on January 18-20, 2013. The goals of the conference were to foster a culture in which undergraduate women are encouraged and supported to pursue, and also to succeed in, higher education in physics; to provide career information to students in physics and related fields; to give women the resources, motivation, and confidence to apply to graduate school and successfully complete a Ph.D. program in Physics; to provide information and dispel misconceptions about the applicationmore » process for graduate school and the diverse employment opportunities in physics and related fields, enabling women to make more informed decisions about their goals and attain them; and to connect female physics students with successful female physicists to whom they can relate and who can act as inspirational role models and mentors.« less
The Early Developments of the Theory of the Mössbauer Effect
NASA Astrophysics Data System (ADS)
Lipkin, Harry J.
I was at the University of Illinois at Urbana in the academic year 1958-1959 when I first heard about the Mössbauer effect. My contacts with Bardeen and his theory group taught me everything I needed to know about solid state physics to understand the Mössbauer effect. I also learned at Urbana from Fred Seitz that my old friend Kundan Singwi had done pioneering work in neutron scattering which was very relevant to the Mössbauer effect. I had met Kundan and his wife Helga in 1953 when we were both postdocs learning about nuclear energy at Saclay, lived in the same pension operated by the French Atomic Energy Commission, and had dinner together every evening. It was a pleasure to renew our contacts after their arrival at Argonne in 1959 when we were both involved in the Mössbauer effect, and during an extended period while he was at Argonne and we visited every summer. I shall miss both John and Kundan.
High Temperature Oxidation and Electrochemical Studies Related to Hot Corrosion.
1987-04-01
University of Illinois Martin Marietta Laboratories Urbana , Ill 61801 1450 South Rolling Rd. Baltimore, MD 21227-3898 Prof. H.W. Pickering Prof. P.J. Moran...N aval Facilities Engineering Defense Metals and Ceramics Com and :nfo-.a:ion Center Alexandria, VA 22331 Battelle Memoria
Planning for Preservation during Mass Digitization Projects
ERIC Educational Resources Information Center
Teper, Jennifer Hain; Shaw, Emily F.
2011-01-01
In anticipation of current and future mass digitization projects in which the University of Illinois at Urbana-Champaign's Library will participate, the Library's Conservation Unit began to gather data on the "scannability" of our general book collections to anticipate potential effects on conservation and preservation work flows. The…
Crime Scene Intelligence. An Experiment in Forensic Entomology
2006-11-01
Investigation (Boca Raton, FL: CRC Press, 1993), 72. 23 Smith, 86. 24 G. Bianchini, “La Biologia Del Cadaver, ” Archivic Antropologia...May R. Ninety-Nine More Maggots, Mites, and Munchers. Urbana and Chi- cago: University of Illinois Press, 1985. Bianchini, G. “La Biologia Del
The Student/Library Computer Science Collaborative
ERIC Educational Resources Information Center
Hahn, Jim
2015-01-01
With funding from an Institute of Museum and Library Services demonstration grant, librarians of the Undergraduate Library at the University of Illinois at Urbana-Champaign partnered with students in computer science courses to design and build student-centered mobile apps. The grant work called for demonstration of student collaboration…
Spring 2006. Industry Study. Environment Study
2006-01-01
sustainability. 91 On the positive side, a 2005 survey found that an increasing number of business schools are offering courses in ethics, corporate...Studies Journal. Urbana: 2000.Vol.28, Iss. 3; pg. 576, 21 pgs. 92 World Resource Institute (WRI) (2005, October 19) Business Schools Respond to New
Khanna, Madhu
2018-02-19
Madhu Khanna from the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute on Competitiveness of Second Generation Biofuel Feedstocks: Role of Technology and Policy on March 25, 2010 at the 5th Annual DOE JGI User Meeting.
Digital Primary Source Materials in the Classroom.
ERIC Educational Resources Information Center
Bennett, Nuala; Trofanenko, Brenda
Digital technologies bring museums, libraries, and archives together to enhance learning by providing access to digitized primary and secondary cultural resources along with the more traditional bibliographic materials. At the University of Illinois at Urbana-Champaign, the University Library and the College of Education are developing a…
Cobertura desarrollada de Puerto Rico
William A. Gould; Sebastian Martinuzzi; Olga M. Ramos Gonzalez
2008-01-01
Este mapa representa la cobertura desarrollada en Puerto Rico (Martinuzzi et al. 2007). Cobertura desarrollada se define aqui como areas urbanas, construidas y sin vegetacion, que resultan de actividad humana. Tipicamente, estas incluyen estructuras construidas, concreto, asfalto, u otra infraestructura. La cobertura desarrollada se creo mediante el analisis de...
User-Oriented Project Accounting System.
ERIC Educational Resources Information Center
Hess, Larry G.; Alcorn, Lisa S.
1990-01-01
The project accounting system used by the University of Illinois Urbana-Champaign School of Chemical Sciences exchanges financial data with the campus' central accounting system and allows integration of this information with user-entered data to produce an easily read, fully obligated project accounting statement for the budget and period…
At this center, researchers study the effects of two endocrine disruptors that are commonly used in pesticides, plastics and many other products and are also found in vehicle exhaust: bisphenol A (BPA) and phthalates.
Jesus Pacheco; Gerardo Ceballos; Georgina Santos; Rurik List; Patricia Manzano; Juan Cruzado
2006-01-01
Biodiversity loss is one of the most severe global environmental problems. Among other factors, it is fostered by the destruction and fragmentation of natural ecosystems. The Chihuahuan prairies merit no exception; a great number of its associated species are endangered by habitat fragmentation or deterioration. The prairie dog (Cynomys spp) illustrates this situation...
Understanding the Effect of Na in Improving the Performance of CuInSe 2 Based Photovoltaics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dobson, Kevin D.
Cu(In,Ga)Se 2 (CIGS) thin film photovoltaic technology is in the early stages of commercialization with an annual manufacturing capacity over 1 GW and has demonstrated the highest module efficiency of any of the thin film technologies. However there still is a lack of fundamental understanding of the relationship between the material properties and solar cell device operation. It is well known that the incorporation of a small amount of Na into the CIGS film during processing is essential for high efficiency devices. However, there are conflicting explanations for how Na behaves at the atomic scale. This report investigates how Namore » is incorporated into the CIGS device structure and evaluates the diffusion of Na into CIGS grain boundaries (GBs) and bulk crystallites. Participants: This project was carried out at the Institute of Energy Conversion at the University of Delaware, collaborating with the Rockett group at the University of Illinois Urbana-Champagne. Significant Findings: The significant outcomes of this project for each task include; Task 1.0: Effect of Na in Devices Fabricated on PVD Deposited CIGS; Na diffusion occurs through the Mo back contact via GBs driven by the presence of oxygen; Na reversibly compensates donor defects in CIGS GBs,Task 2.0: Na Incorporation in Single Crystal CIGS; and bulk Na diffusion proceeds rapidly such that grains are Na-saturated immediately following CIGS thin film manufacture. Industry Guidance: The presented results offer interesting concepts for modification of manufacturing processes of CIGS-based PV modules. Possible approaches to improve control of Na uptake and uniformly increase levels in CIGS films are highlighted for processes that employ either soda-lime glass or NaF as the Na source. Concepts include the potential of O 2 or oxidative based treatments of Mo back contacts to improve Na diffusion through the metal film and increase Na uptake into the growing CIGS. This project has also offered fundamental understanding of the behavior of Na in CIGS grains and GBs, particularly the confirmation that CIGS grains will be saturated with Na immediately following manufacture Summary of Results: Most commercially available CIGS modules are fabricated on soda-lime glass coated with Mo as the back electric contact, and Na in the glass diffuses through the Mo layer into the CIGS during film growth. In Task 1 the transport of Na through Mo was evaluated using x-ray photoelectron surface spectroscopy along with diffusion modeling to obtain diffusion coefficients at several temperatures. It was determined that Na diffusion in Mo only occurs along GBs and that oxygen provides an additional driving force to enhance Na transport. Device data revealed that older Mo substrates with a greater amount of surface oxide resulted in slightly higher efficiencies due to enhanced Na incorporation caused by the oxide. This finding shows that Mo substrates could potentially undergo an oxidation treatment prior to CIGS deposition to further improve and control the incorporation of Na. To determine if in-grain Na affects device performance, in Task 1 Na was selectively removed from GBs using heat/rinse cycles. Due to the low temperature of this treatment, Na at GBS remained mobile while diffusion within the bulk was too slow for Na removal from the grain interiors. Changes in electrical properties were evaluated using conductivity and Seebeck coefficient measurements, with both decreasing as Na was removed to reach values similar to Na-free controls samples. This can be explained by the compensation of donor defects by Na, causing an increase in the free carrier concentration. Devices showed a decrease in open-circuit voltage after Na removal confirming that the beneficial effects of GB Na. The findings of this project will provide guidance for rational optimization of Na incorporation procedures in the manufacturing of CIGS solar cells. While it is known that Na segregates at CIGS GBs, the nature and role of Na diffusion into grain interiors was less clear. In Task 2, single crystal CuInSe 2 was used as a model system to represent the grain interiors of CIGS. Crystals processed by two different methods of different compositions and dislocation densities, were evaluated. Diffusion coefficients were obtained at two temperatures after Na diffusion, giving near identical values, ~2x10 11 cm 2/s and ~6x10 11 cm2/s at 420°C and 480°C, respectively, for each crystal. Characterization confirmed that dislocation densities were too low to significantly impact the effective diffusion coefficient. The Cu-poor crystal had a higher solubility suggesting that Na diffusion is mediated by Cu-vacancies, but was not accompanied by an expected increase in diffusion coefficient. The activation energy for diffusion was similar to values expected for interstitial diffusion, but the large size of Na + ions should result in a solubility that is much lower than what was experimentally measured. A hybrid interstitial-substitutional mechanism is proposed that combines the fast diffusion of interstitial atoms with the high solubility common for substitutional impurities. Lattice diffusion of Na proceeds fast enough that CIGS grain interiors will have Na concentrations near the solubility limit of 1018 cm -3 when manufactured under standard conditions. Na and K treated epitaxial CIS films showed a significant increase in cathodoluminescence emission intensity, indicating a reduction of non-radiative recombination pathways, which is consistent with improvements in CIGS device performance, though the mechanism is not clear. Pathways forward: Despite the success of this project, there are a number of questions remaining related to further the understanding of the chemistry of Na in CIGS films and devices. These include further elucidation of the mechanisms of Na passivation in CIGS GBs, with identification of which defects are involved and confirmation of the possible effects of in-grain Na on device performance. To complete analysis of the cell structure, conformation of the presence and possible chemistries of Na at the CIGS/CdS junction and/or in the front transparent contacts, and its effects on device performance, is needed.« less
Talking and Thinking about Qualitative Research
ERIC Educational Resources Information Center
Ellis, Carolyn; Bochner, Arthur; Denzin, Norman; Lincoln, Yvonna; Morse, Janice; Pelias, Ronald; Richardson, Laurel
2008-01-01
This script comes from an edited transcript of a session titled "Talking and Thinking About Qualitative Research," which was part of the 2006 International Congress of Qualitative Inquiry, held at the University of Illinois at Urbana-Champaign on May 4-6, 2006. This special session featured scholars informally responding to questions about their…
The Public Image of the Military as Reflected in Leading Magazines, (1982-1983).
1984-06-01
a-I. n America Middle East Vietnam War POW s Vietnam Memoria ; -’-. -. -:-’u...Naw Es±laamaal.: Aamad Eozaa aa Amaa Soie.±, by Char]les C. Moskos, Jr. Peterson, Theodore. Mgzims.s .Lm ±.a I ±~*.~£~.~ Urbana : University of
High Temperature Oxidation and Electrochemical Studies Related to Hot Corrosion.
1987-12-01
Birnbaum Dept. of Metallurgy & Mining Eng. Dr. W. C. Moshier University of Illinois Martin Marietta Laboratories Urbana , Ill 61801 1450 South...Defense Metals and Ceramics Command Infor-r.ation Center Alexandria, VA 22331 Battelle Memoria !nsri~ure ATTn: Code 03 1 505 King Avenue Columbus, OH
CHOICES. A Resource for Literacy Providers and Homeless Families.
ERIC Educational Resources Information Center
Koehler, Gwen; And Others
CHOICES, a literacy program for homeless families, piloted a program at the Women's Emergency Shelter in Champaign, Illinois and later expanded its services to A Woman's Place, a domestic violence shelter, in Urbana, Illinois. The CHOICES program offered weekly language activities for the children and gave mothers information about developing…
ERIC Educational Resources Information Center
Stewart, Pearl
2011-01-01
In early 2010, Stig Lanesskog, associate dean for the MBA program at the University of Illinois at Urbana-Champaign, challenged a group of his students to venture beyond classroom polemics and into the lives of people in need. Lanesskog took them to South Dakota's Pine Ridge Reservation, a culturally rich and economically devastated area with…
Automated Interactive Storeroom Inventory System.
ERIC Educational Resources Information Center
Sapp, Albert L.; Hess, Larry G.
1989-01-01
The inventory system designed for six storerooms in three buildings at the University of Illinois at Urbana-Champaign's School of Chemical Sciences replaced an issue-slip and transactions record system with barcode technology. Data collection error reductions have been significant, making it easier to determine stock levels and plan purchases.…
DeLucia, Evan
2018-02-13
Evan DeLucia of the University of Illinois at Urbana-Champaign and the Energy Biosciences Institute talks about The Promise and Challenge of Producing Biofuel Feedstocks: An Ecological Perspective on March 25, 2010 at the 5th Annual DOE JGI User Meeting.
Illinois Tech Prep Planning Strategies.
ERIC Educational Resources Information Center
Illinois Univ., Urbana. Dept. of Vocational and Technical Education.
This tech prep planning handbook is based on the research conducted at the Office of Community College Research and Leadership, University of Illinois at Urbana-Champaign. The study involved information gathering procedures at each of the 17 tech prep pilot sites about their planning activities. Seven sections are included: (1) tech prep in…
A Solution Method for Large Deformation Contact Problems.
1984-10-01
15] Desai, C.S., Zaman, M.M., Lightner , J.G., and Siriwardane, H.J., "Thin Element for Interfaces and Joints," Int. J. Anal. and Num. Meth. in...Urbana, IL 61801 SMCCR-SPS-IL 1 Massachusetts Institute of Technology Aeroelastic and Structures Research Laboratory ATTN: Dr. E. A. Witmer Cambridge
Microcomputer Applications in Local Assessment Systems.
ERIC Educational Resources Information Center
Harnisch, Delwyn L.; And Others
The capabilities and hardware requirements of four microcomputer software packages produced by the Office of Educational Testing, Research and Service at the University of Illinois at Urbana-Champaign are described. These programs are: (1) the Scan-Tron Forms Analysis Package Version 2.0, an interface between an IBM-compatible and a Scan-Tron…
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Students Faculty & Staff Alumni Parents Campus Resources The Next 150 Strategic Plan Inclusive Illinois Search Directory Quicklinks A-Z Index & Directory Map Library Give Now Resources for Students Faculty & Staff Alumni Parents About About Links Overview Leadership Facts Research Milestones Nobels &
Virtual Service, Real Data: Results of a Pilot Study.
ERIC Educational Resources Information Center
Kibbee, Jo; Ward, David; Ma, Wei
2002-01-01
Describes a pilot project at the University of Illinois at Urbana-Champaign reference and undergraduate libraries to test the feasibility of offering real-time online reference service via their Web site. Discusses software selection, policies and procedures, promotion and marketing, user interface, training and staffing, data collection, and…
NSF Says It Will Support Supercomputer Centers in California and Illinois.
ERIC Educational Resources Information Center
Strosnider, Kim; Young, Jeffrey R.
1997-01-01
The National Science Foundation will increase support for supercomputer centers at the University of California, San Diego and the University of Illinois, Urbana-Champaign, while leaving unclear the status of the program at Cornell University (New York) and a cooperative Carnegie-Mellon University (Pennsylvania) and University of Pittsburgh…
Educational benefits of green chemistry
NASA Astrophysics Data System (ADS)
Desmond, Serenity; Ray, Christian; Andino Martínez, José G.
2017-08-01
In this article, we present our current state of affairs in the "greening" of general chemistry laboratories, at the University of Illinois at Urbana-Champaign. We recognize the need to quantify our environmental mark and what we plan to do to continue to strive to make our work more sustainable and educational.
Can Vet Schools Teach without Killing Animals?
ERIC Educational Resources Information Center
Mangan, Katherine S.
2000-01-01
Discusses a protest by students at the University of Illinois (Urbana) College of Veterinary Medicine over the killing of animals that led to temporary curtailing of lethal animal experiments. Examines the conflict between animal rights groups and some faculty who are openly skeptical about the effectiveness of alternatives to the hands-on…
STEM Leader from the Roeper School: An Interview with Nuclear Engineer Clair J. Sullivan
ERIC Educational Resources Information Center
Ambrose, Don
2016-01-01
Clair J. Sullivan is an assistant professor in the Department of Nuclear, Plasma and Radiological Engineering at the University of Illinois at Urbana-Champaign (UIUC). Her research interests include radiation detection and measurements; gamma-ray spectroscopy; automated isotope identification algorithms; nuclear forensics; nuclear security;…
Propagation of Regional Phases in the Basin and Range
1990-02-02
complex miultiple rupture, Bull. Seusmol. Soc. Am., 57, 1017 W i23 K un.rT~I, "aind G. S. Stew art, Seismologica aspects of she Gutemala 1967...Fred K. Lamb Prof. William Menke University of Illinois at Urbana-Champaign Lamont-Doherty Geological Observatory Department of Physics of Columbia
A Visual Construct on the Role of the Teacher in Multicultural Education.
ERIC Educational Resources Information Center
Stuckman, Ralph E.
This paper describes an undergraduate teacher education course offered at Urbana University (Ohio). The course introduces preservice teachers to the nature of multiculturalism in terms of economic, social, intellectual, age, and gender differences, leading participants to explore this educational process from sociological and psychological…
Over, Thomas M.; Soong, David T.; Holmes, Robert R.
2011-01-01
Boneyard Creek—which drains an urbanized watershed in the cities of Champaign and Urbana, Illinois, including part of the University of Illinois at Urbana-Champaign (UIUC) campus—has historically been prone to flooding. Using the Stormwater Management Model (SWMM), a hydrologic and hydraulic model of Boneyard Creek was developed for the design of the projects making up the first phase of a long-term plan for flood control on Boneyard Creek, and the construction of the projects was completed in May 2003. The U.S. Geological Survey, in cooperation with the Cities of Champaign and Urbana and UIUC, installed and operated stream and rain gages in order to obtain data for evaluation of the design-model simulations. In this study, design-model simulations were evaluated by using observed postconstruction precipitation and peak-discharge data. Between May 2003 and September 2008, five high-flow events on Boneyard Creek satisfied the study criterion. The five events were simulated with the design model by using observed precipitation. The simulations were run with two different values of the parameter controlling the soil moisture at the beginning of the storms and two different ways of spatially distributing the precipitation, making a total of four simulation scenarios. The simulated and observed peak discharges and stages were compared at gaged locations along the Creek. The discharge at one of these locations was deemed to be critical for evaluating the design model. The uncertainty of the measured peak discharge was also estimated at the critical location with a method based on linear regression of the stage and discharge relation, an estimate of the uncertainty of the acoustic Doppler velocity meter measurements, and the uncertainty of the stage measurements. For four of the five events, the simulated peak discharges lie within the 95-percent confidence interval of the observed peak discharges at the critical location; the fifth was just outside the upper end of this interval. For two of the four simulation scenarios, the simulation results for one event at the critical location were numerically unstable in the vicinity of the discharge peak. For the remaining scenarios, the simulated peak discharges over the five events at the critical location differ from the observed peak discharges (simulated minus observed) by an average of 7.7 and -1.5 percent, respectively. The simulated peak discharges over the four events for which all scenarios have numerically stable results at the critical location differs from the observed peak discharges (simulated minus observed) by an average of -6.8, 4.0, -5.4, and 1.5 percent, for the four scenarios, respectively. Overall, the discharge peaks simulated for this study at the critical location are approximately balanced between overprediction and underprediction and do not indicate significant model bias or inaccuracy. Additional comparisons were made by using peak stages at the critical location and two additional sites and using peak discharges at one additional site. These comparisons showed the same pattern of differences between observed and simulated values across events but varying biases depending on streamgage and measurement type (discharge or stage). Altogether, the results from this study show no clear evidence that the design model is significantly inaccurate or biased and, therefore, no clear evidence that the modeled flood-control projects in Champaign and on the University of Illinois campus have increased flood stages or discharges downstream in Urbana.
Technological Change and Rural Development: A Case Example from Illinois.
ERIC Educational Resources Information Center
Hoke, Gordon
In 1980, the Office of Continuing Education and Public Service at the University of Illinois at Urbana-Champaign acquired a W. K. Kellogg Foundation grant to establish a 4-year model Community Information and Education Service (CIES). Working with the university's Cooperative Extension Service and five community colleges, CIES initially focused on…
Problems and Failures in Library Automation.
ERIC Educational Resources Information Center
Lancaster, F. Wilfrid, Ed.
Drawn from the 15th Annual Clinic on Library Applications of Data Processing, held at the University of Illinois at Urbana-Champaign, the nine papers presented in this volume deal with problems--or, in some cases, downright failures--in the automation of various facets of library service. They range from a general survey of failures or limitations…
Policing the New World Disorder: Peace Operations and Public Security
1998-01-01
Ministerio de Justicia, 1993). 25IUDOP, "La delincuencia urbana," Estudios Centroamericanos 534-545 (April/May 1993), 471-79. "Report of the Director...and Special Forces were used for urgently needed repairs. A special prison was established for women and juveniles in Port-au-Prince to separate them
Using and Evaluating Differential Modeling in Intelligent Tutoring and Apprentice Learning Systems.
1987-01-01
medical diagnosis (Buchanan and Shortliffe, 1984); student hypothesis errors are discovered in the process of conducting a Socratic dialogue. Recent... Jose Mestre Pit-sb r h, PA 15213 Urbana, IL 61801 Department of Physics D- %iDHasbrouck Laboratory A; Jilr ieLaKin Dr. Don Lyon University of
ERIC Educational Resources Information Center
Lenkart, Joe; Teper, Thomas H.; Thacker, Mara; Witt, Steven W.
2015-01-01
To evaluate the current state of resource sharing and cooperative collection development, this paper examines the relationship between less commonly taught language collections (LCTL) and ILL services. The study examined multiple years of the University of Illinois at Urbana-Champaign's resource-sharing data. This paper provides a historical…
ERIC Educational Resources Information Center
Searing, Susan E.
2007-01-01
Information literacy instruction is integrated into the distance education program in library and information science (LEEP) at the University of Illinois, Urbana-Champaign (UIUC). This article describes the LEEP program and the library services provided to its students. Published research on LEEP and related topics in librarianship is reviewed.…
Sediment Budget on the Indiana Shore at Burns Harbor, Lake Michigan
2015-05-15
formation of the Indiana Dunes 146 20/03/2015 16 pp 3 National Lakeshore (Engel 1983, Franklin and Schaeffer 1983, Higgs 1995). The Harbor is a...shores of Lake Michigan,” University of Illinois Press, Urbana, IL, 278 p. Higgs , S. (1995). “Eternal Vigilance: Nine Tales of Environmental
The Age of the Supercomputer Gives Way to the Age of the Super Infrastructure.
ERIC Educational Resources Information Center
Young, Jeffrey R.
1997-01-01
In October 1997, the National Science Foundation will discontinue financial support for two university-based supercomputer facilities to concentrate resources on partnerships led by facilities at the University of California, San Diego and the University of Illinois, Urbana-Champaign. The reconfigured program will develop more user-friendly and…
Assessing Digital Humanities Tools: Use of Scalar at a Research University
ERIC Educational Resources Information Center
Tracy, Daniel G.
2016-01-01
As librarians increasingly support digital publication platforms, they must also understand the user experience of these tools. This case study assesses use of Scalar, a digital humanities publishing platform for media-rich projects, at the University of Illinois at Urbana-Champaign. Based on a survey, interviews, and content analysis, the study…
ERIC Educational Resources Information Center
Levin, Sandra R.; Levin, James A.; Guell, James G.; Waddoups, Gregory L.
2002-01-01
Describes a Master of Education program at the University of Illinois, Urbana-Champaign called Curriculum, Technology, and Education Reform OnLine (CTER) that is aimed at K-12 teachers. The evaluation based on program stakeholders includes interface design; instructional design; faculty satisfaction; student attitudes; economic viability;…
Massive Open Online Courses (MOOCs): Participant Activity, Demographics, and Satisfaction
ERIC Educational Resources Information Center
Shrader, Sara; Wu, Maryalice; Owens, Dawn; Santa Ana, Kathleen
2016-01-01
This paper examines activity patterns, participant demographics, and levels of satisfaction in multiple MOOC offerings at the University of Illinois at Urbana-Champaign from August 2012-December 2013. Using the following guiding questions: "Who are MOOC participants, how do they participate, and were they able to get what they wanted out of…
A Teaching Artist in Rural Schools: Sowing Seeds for Creative Expression
ERIC Educational Resources Information Center
Kuper, Kate
2006-01-01
For nearly 25 years, the author has driven the highways and back roads of Illinois, teaching dance to school children, leading family programs, performing lecture/demonstrations, and choreographing technically simple, conceptually complex pieces with and for young dancers. The author's home base is Champaign/Urbana (C/U), twin cities with a…
Data Management Practices and Perspectives of Atmospheric Scientists and Engineering Faculty
ERIC Educational Resources Information Center
Wiley, Christie; Mischo, William H.
2016-01-01
This article analyzes 21 in-depth interviews of engineering and atmospheric science faculty at the University of Illinois Urbana-Champaign (UIUC) to determine faculty data management practices and needs within the context of their research activities. A detailed literature review of previous large-scale and institutional surveys and interviews…
Microwave Processing of Materials
1994-01-01
up to many meters in electrically insulating materials, such as ceramics, polymers, and certain composite materials. As discussed in Chapter 2, the...for University of Illinois, Urbana Center: High Performance Polymeric Materials Technology 1206 West Green Street Adhesives & Composites United...Michigan State University, application of microwave processing to polymers and polymer composites Dr. Raymond Decker, University Science Partners
A Wireless Platform for Energy Efficient Building Control Retrofits
2012-08-01
University of Illinois at Urbana Champaign UTRC United Technologies Research Center VFD variable frequency drive WSN wireless sensor network ...demonstration area. .............................................................. 16 Table 4. Cost model for wireless sensor network ...buildings with MPC-based whole-building optimal control and (2) reduction in first costs achievable with a wireless sensor network (WSN)-based
Creating Fee-Based Online Services: A New Role for Academic Librarians.
ERIC Educational Resources Information Center
Trehub, Aaron
1999-01-01
Discussion of the impact of the Internet on libraries focuses on librarians as creators and marketers of new online services. Describes two fee-based online services at the University of Illinois at Urbana-Champaign and concludes that academic libraries have the ability to create new online services, especially reference services. (Author/LRW)
ERIC Educational Resources Information Center
Chang, May
2000-01-01
Describes the development of electronic finding aids for archives at the University of Illinois, Urbana-Champaign that used XML (extensible markup language) and EAD (encoded archival description) to enable more flexible information management and retrieval than using MARC or a relational database management system. EAD template is appended.…
Albertson, Justin P; Clegg, Whitney J; Reid, Heather D; Arbise, Benjamin S; Pryde, Julie; Vaid, Awais; Thompson-Brown, Rachella; Echols, Fredrick
2016-07-29
Mumps is an acute viral disease characterized by fever and swelling of the parotid or other salivary glands. On May 1, 2015, the Illinois Department of Public Health (IDPH) confirmed a mumps outbreak at the University of Illinois at Urbana-Champaign. IDPH and the Champaign-Urbana Public Health District (C-UPHD) conducted an investigation and identified 317 cases of mumps during April 2015-May 2016. Because of sustained transmission in a population with high 2-dose coverage with measles-mumps-rubella (MMR) vaccine, a third MMR dose was recommended by IDPH, C-UPHD, and the university's McKinley Health Center. No formal recommendation for or against the use of a third MMR dose has been issued by the Advisory Committee on Immunization Practices (ACIP) (1). However, CDC has provided guidelines for use of a third dose as a control measure during mumps outbreaks in settings in which persons are in close contact with one another, where transmission is sustained despite high 2-dose MMR coverage, and when traditional control measures fail to slow transmission (2).
Sosa-Rubí, Sandra G; Salinas-Rodríguez, Aarón; Galárraga, Omar
2016-01-01
Objetivo Estimar el efecto del Seguro Popular (SP) sobre la incidencia del gasto catastrófico en salud (GCS) y sobre el gasto de bolsillo en salud (GBS) en el mediano plazo. Material y métodos Con base en la Encuesta de Evaluación del Seguro Popular (2005–2008), se analizaron los resultados del efecto del SP en la cohorte rural para dos años de seguimiento (2006 y 2008) y en la cohorte urbana para un año (2008). Resultados A nivel conglomerado no se detectaron efectos del SP. A nivel hogar se encontró que el SP tiene un efecto protector en el GCS y en el GBS en consulta externa y hospitalización en zonas rurales; y efectos significativos en la reducción de GBS en consulta externa en zonas urbanas. Conclusiones El SP se muestra como un programa efectivo para proteger a los hogares contra gastos de bolsillo por motivos de salud en el mediano plazo. PMID:22282205
NASA Technical Reports Server (NTRS)
Weiland, R. M.; Bowhill, S. A.
1981-01-01
The development and first observations of the partial-reflection drifts experiment at Urbana, Illinois (40 N) are described. The winds data from the drifts experiment are compared with electron concentration data obtained by the differential-absorption technique to study the possible meteorological causes of the winter anomaly in the mesosphere at midlatitudes. winds data obtained by the meteor-radar experiment at Urbana are also compared with electron concentration data measured at Urban. A significant correlation is shown is both cases between southward winds and increasing electron concentration measured at the same location during winter. The possibility of stratospheric/mesospheric coupling is investigated by comparing satellite-measured 0.4 mbar geopotential data with mesospheric electron concentration data. No significant coupling was observed. The winds measured at Saskatoon, Saskatchewan (52 N) are compared with the electron concentrations measured at Urban, yielding constant fixed relationship, but significant correlations for short segments of the winter. A significant coherence is observed at discrete frequencies during segments of the winter.
Transmission scenarios of major vector-borne diseases in Colombia, 1990-2016.
Padilla, Julio César; Lizarazo, Fredy Eberto; Murillo, Olga Lucía; Mendigaña, Fernando Antonio; Pachón, Edwin; Vera, Mauricio Javier
2017-03-29
Introducción. Las enfermedades transmitidas por vectores representan más de 17 % de todas las enfermedades infecciosas y causan anualmente un millón de defunciones a nivel mundial. En Colombia, la malaria, el dengue, la enfermedad de Chagas y las leishmaniasis son condiciones endemoepidémicas persistentes.Objetivo. Determinar el comportamiento epidemiológico de las enfermedades transmitidas por vectores en zonas urbanas y rurales de Colombia entre 1990 y 2016.Materiales y métodos. Se hizo un estudio descriptivo del comportamiento epidemiológico de las principales enfermedades transmitidas por vectores en zonas urbanas y rurales de Colombia entre 1990 y 2016, con la información proveniente de fuentes oficiales secundarias.Resultados. En el periodo estudiado se registraron 5'360.134 casos de enfermedades transmitidas por vectores, de los cuales 54,7 % fueron de malaria y 24,9 % de dengue. Estos casos concentraron el 80 % de la carga acumulada de casos de enfermedades transmitidas por vectores. Las medianas de las tasas de incidencia fueron 1.371 y 188 por 100.00 habitantes para malaria y dengue, respectivamente. Además, los casos de chikungunya fueron 774.831 desde su introducción en el 2014 y, los de Zika, 117.674 desde su aparición en 2015. En las zonas rurales predominaron las enfermedades parasitarias transmitidas por vectores como la malaria, las leishmaniasis y la enfermedad de Chagas. A nivel urbano, predominaron el dengue, el chikungunya y el Zika.Conclusiones. La transmisión en Colombia de estas enfermedades es persistente en las zonas urbanas y en las rurales, y de tipo endemoepidémico en los casos de malaria, dengue, leishmaniasis y enfermedad de Chagas. Dicha transmisión se ha dado de manera focalizada y con patrones variables de intensidad. Asimismo, se mantienen las condiciones que han favorecido la transmisión emergente de nuevas arbovirosis.
Diversidad de aves en agropaisajes en la region norte de Nicaragua
Wayne J. Arendt; Marvin Tórrez; Sergio Vílchez
2012-01-01
Avian diversity in agroscapes in Nicaraguaâs north highlands. â Nicaraguaâs highland forests are threatened by continual wood extraction and encroaching agriculture. Still, the effects of forest loss and fragmentation on avian communities remain little known. We used fixed-width point counts (distance sampling: 4843 detections during 86 h of observation) to...
ERIC Educational Resources Information Center
Office of English Language Acquisition, Language Enhancement, and Academic Achievement for Limited English Proficient Students (ED), Washington, DC.
The brochure, written in Spanish, briefly outlines the U.S. Department of Education's most recent policy on educating students with diverse linguistic and cultural backgrounds. It states the Department's mission, describes today's student population, and outlines the role of the Office of English Language Acquisition, Language Enhancement and…
Connecting Families through Innovative Technology in an Early Childhood Gifted Program.
ERIC Educational Resources Information Center
Kristovich, Sharon; Hertzog, Nancy B.; Klein, Marjorie
University Primary School (UPS) is an early childhood gifted program affiliated with the University of Illinois at Urbana-Champaign. This paper highlights three innovative uses of technology at UPS: Knowledge Web pages, photo portfolios, and Chickscope. The Knowledge Web pages are a collection of Web pages that serve as a virtual bulletin board…
Investigating Textbook Reserves: A Case Study of Two Models for Reserves Collections
ERIC Educational Resources Information Center
Pitts-Noggle, Stephanie; Rafferty, Ryan
2017-01-01
This article examines the behaviors and preferences of medical and nursing students in relation to their required textbooks and library reserves. The findings are based on an April 2015 survey at the University of Illinois-Chicago satellite Library of the Health Sciences in Urbana, where the library provides access to textbooks through traditional…
1991-05-01
Plant Biology); Carol Augspurger 376 INSTITUTION; COOPERATOR University of Illinois, Urbana ( Ecology , Ethology & Evolution ...43 Ph.D. 33 33 33 1 STRENGTHS AND SPECIALTIES Subject Matter Strengths: Biogeography, community ecology , vertebrate ecology , plant /insect interactions ... ecology , population ecology of small mammals, avian ecology , plant /animal interactions . Formal Teaching/Research Arrangements With Other
Symposium on Early Childhood Education (Urbana-Champaign, Illinois, November 9-10, 1997). Abstracts.
ERIC Educational Resources Information Center
Illinois Univ., Champaign. Coll. of Education.
This book compiles abstracts of presentations from a symposium held in honor of Dr. Bernard Spodek, a leading scholar in early childhood education, on the occasion of his retirement. Topics addressed are as follows: (1) culture in early childhood curriculum; (2) developmental and cultural appropriateness; (3) kindergarten in Japan; (4) pressure…
Instructivo del Alfabetizador: Poblacion Urbana (Reading and Writing Instruction: Urban Population).
ERIC Educational Resources Information Center
Instituto Nacional para la Educacion de los Adultos, Mexico City (Mexico).
This series of instructional materials is designed for Spanish speaking adults in Mexico who are in the process of becoming literate or have recently become literate in their native language. The reading/writing workbook is presented in two volumes along with a teacher's manual for an adult literacy program directed at urban inhabitants of Mexico.…
1980-09-01
University, Department of Electrical Engineering, Sept. 1975. 18 9. J. L. Bogdanor , R. A. Rearlman, and M. D. Siegel, "Intrasystem Electromagnetic...34 IRE Transactions on Antennas and Propa- gation, May 1962, pp. 264-273. 11. J. L. Bogdanor , R. A. Pearlman, and M. D. Siegel, "Intrasystem
Solid State Cooling with Advanced Oxide Materials
2014-06-03
Department of Materials Science and Engineering , Department of Mechanical Science and Engineering , and Department of Electrical and Computer... Engineering University of Illinois, Urbana-Champaign Program Overview The focus of this program was to probe electro-(magneto-)caloric materials for... engineering systems by developing theoretical and experimental approaches to study thermodynamic properties and effects in thin film systems. Despite
Papers in African Linguistics. Current Inquiry into Language and Linguistics I.
ERIC Educational Resources Information Center
Kim, Chin-Wu, Ed.; Stahlke, Herbert, Ed.
This volume, a collection of selected papers from the Conference on African Languages and Linguistics organized by the Department of Linguistics of the University of Illinois and held at Urbana-Champaign on April 24-25, 1970, contains: W. E. Welmers, "The Typology of the Proto-Niger-Kordofanian Noun Class System"; D. Dalby, "A…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-22
...) to provide official services under the United States Grain Standards Act (USGSA), as amended. In... March 31, 2016. Interested persons may obtain official services by contacting these agencies at the... Designation end Champaign Urbana, IL, (217) 344-9306..... 4/1/2013 3/31/2016 Section 79(f) of the USGSA...
Training the Future - Swamp Work Activities
2017-07-19
In the Swamp Works laboratory at NASA's Kennedy Space Center in Florida, student interns such as Kevin Murphy are joining agency scientists, contributing in the area of Exploration Research and Technology. Murphy is majoring in mechanical engineering at the University of Illinois at Urbana-Champaign. The agency attracts its future workforce through the NASA Internship, Fellowships and Scholarships, or NIFS, Program.
AACR2 Impact and OCLC Cataloging.
ERIC Educational Resources Information Center
Clark, Sharon E.; Lenzini, Rebecca T.
This paper analyzes the impact of adopting the Anglo-American Cataloging Rules, second edition (AACR2), upon cataloging at the library of the University of Illinois at Urbana-Champaign. The staffing and workflow of the OCLC unit which incorporated AACR2 is described and figures are reported on the effects of AACR2 application as measured on the…
Integral Manifold in System Design with Application to Flexible Link Robot Control
1988-06-01
environment. I am very grateful to my advisor . Professor Kokotovic. whose insight and guidance in my research work led me to the beginning of my...MANIFOLD IN SVSTEM DESIGN WITH RPLICATION TT 2Z2 FLEXIBLE LINK ROBO (U) ILLINOIS UNIV AT URBANA DECISION AND CONTROL LAB H C TSENG JUN 98
ERIC Educational Resources Information Center
Tworek, Richard K.; Campbell, Edward L.
A study was conducted in the Champaign-Urbana area to evaluate the relationship of the educational preparation of medical transcriptionists to their on-the-job requirements. Personal interviews were conducted with three hospital medical records administrators and with the appropriate department head of an area community college that offered a…
O Universo das Sociedades Numa Perspectiva Relativa: Exercícios de Etnoastronomia
NASA Astrophysics Data System (ADS)
Fares, Érika Akel; Pessoa Martins, Karla; Maciel Araujo, Lidiane; Sauma Filho, Michel
2004-12-01
This work developed at the Planetarium of Pará employing workshops designed for visitor schools (public, private, specials groups), promotes the popularization of the Ethnoastronomy with the aim of diffusing values based on a cultural diversity tolerance and the need of harmonic interplay between people and environment. Using stories and debates, the relationship between humans and the Cosmos is traced from antiquity until today, with the help of slides as a didactic resource. Thus, many conceptions about the origin of the Universe are shown; as well as some constellations created along the History, ending with the present scientific manner of know and explain the World. We then demonstrate the links between space, time and culture with the Cosmos vision. The need to think the World within a plural context to create respect for other different persons is emphasized. Este trabalho, desenvolvido no Planetário do Pará através de oficinas com escolas visitantes (públicas, privadas e grupos especiais), promove a popularização da Etnoastronomia, com o objetivo de difundir valores pautados na tolerância à diversidade cultural e na necessidade da convivência harmônica entre o ser humano e o meio ambiente. Através da contação de histórias e promoção de debate, é tratada a relação dos humanos com o céu desde a antiguidade até os dias atuais, tendo como apoio didático o uso de slides. Assim, são mostradas diversas concepções de origem do Universo; algumas constelações criadas no decorrer da História; e a atual forma científica de conhecer e explicar o mundo. Demonstrando-se, então, a interligação entre espaço, tempo e cultura com a visão do Cosmo. Enfatiza-se a necessidade de se pensar o mundo numa perspectiva relativa ou plural, de forma a propiciar o respeito ao ser diferente.
ERIC Educational Resources Information Center
Divilbiss, J. L., Ed.
Eight studies by experts in the field of information retrieval examine aspects of public use of such automated systems as online catalogs in libraries. Ward Shaw discusses "Design Principles for Public Access," outlining desirable characteristics of an information retrieval system. Allen Avner and H. George Friedman, Jr. treat problems…
Formation of Silicon Nitride Structures by Direct Electron-Beam Writing.
1982-02-01
Urbana, Illinois 73 ii To My Very Own Sivvy ...We have come so far, it is over... from "Edge" by Sylvia Plath I p2" -,i ’- ’.’ . --’ -o . o...1 bellows custom fabricated from type 304 LN stainless steel, which is fully rated for cryogenic service. On the subject of service life , we should
ERIC Educational Resources Information Center
Katz, Lilian G., Ed.; Rothenberg, Dianne, Ed.; Preece, Laurel
2003-01-01
Early Childhood Research and Practice (ECRP), a peer-reviewed Internet-only journal sponsored by the Early Childhood and Parenting (ECAP) Collaborative at the University of Illinois at Urbana-Champaign, covers topics related to the development, care, and education of children from birth to approximately age 8. The journal emphasizes articles…
ERIC Educational Resources Information Center
Groppel, Jack L., Ed.; Sears, Ronald G., Ed.
Researchers, coaches, and players of racquet sports were brought together for this symposium on four racquet sports. Although most of the papers presented at the symposium were written by Americans, one of the speakers was from Canada, and another was from Australia. The sports represented were badminton, racquetball, tennis, and squash. In Part…
ERIC Educational Resources Information Center
Groppel, Jack L., Ed.
Conference proceedings from this national symposium on hard scientific research and developments in teaching tennis, squash, racquetball, and badminton are divided into several sections. The first deals with sports medicine and the biomechanics of the racquet sports. The second part discusses the pyschological and sociological aspects of…
NASA Technical Reports Server (NTRS)
Goodman, Jerry Ronald
2006-01-01
This thesis presents a frame work for a crew station handbook and includes samples of the broader areas which such a handbook should cover. The completed sections of this thesis serve as extensive treatments of the topics covered. The content of the individual sections of Chapters I and II varied with my experience and knowledge.
ERIC Educational Resources Information Center
Instituto Nacional para la Educacion de los Adultos, Mexico City (Mexico).
This document describes literacy models for urban and rural populations in Mexico. It contains four sections. The first two sections (generalizations about the population and considerations about the teaching of adults) discuss the environment that creates illiterate adults and also describe some of the conditions under which learning takes place…
Side by Side: What a Comparative Usability Study Told Us about a Web Site Redesign
ERIC Educational Resources Information Center
Dougan, Kirstin; Fulton, Camilla
2009-01-01
Library Web sites must compete against easy-to-use sites, such as Google Scholar, Google Books, and Wikipedia, for students' time and attention. Library Web sites must therefore be designed with aesthetics and user perceptions at the forefront. The Music and Performing Arts Library at Urbana-Champaign's Web site was overcrowded and in much need of…
Uso de terreno urbano y rural en Puerto Rico
Sebastian Martinuzzi; William A. Gould; Olga M. Ramos Gonzalez; Maya Quinones; Michael E. Jimenez
2008-01-01
El Proyecto de Analisis de Gap de Puerto Rico (PRGAP) (Gould et al. 2008) desarrollo tres usos de terrenos para Puerto Rico: Urbano, Suburbano, y Rural (Martinuzzi et al. 2007). Estas regiones tambien pueden ser consideradas como urbano, densamente-poblado rural, y escasamente-poblado rural, o como urbano y area silvestre con una interfase de area silvestre-urbana. La...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-07-01
This interdisciplinary laboratory in the College of Engineering support research in areas of condensed matter physics, solid state chemistry, and materials science. These research programs are developed with the assistance of faculty, students, and research associates in the departments of Physics, Materials Science and Engineering, chemistry, Chemical Engineering, Electrical Engineering, Mechanical Engineering, and Nuclear Engineering.
Dimensions of Familism among Hispanic and Mainstream Navy Recruits
1982-04-01
Speaking Mental Health Research Center Urbana-Champaign University of California, Los Angeles Judith Lisansky & Bei-Hung Chang University of Illinois...Culture, disease, and stress among Latino immigEants. Washington: Research Institute on Immigration and Ethnic Studies, Smithsonian Institute, 1979...D.C.: Institute of Comparative Social & Cultural Studies, Inc., 1978. Szapocznik, j. A prograumatic mental health approach to enhancing the meaning of
Practical Techniques for Language Design and Prototyping
2005-01-01
Practical Techniques for Language Design and Prototyping Mark-Oliver Stehr1 and Carolyn L. Talcott2 1 University of Illinois at Urbana-Champaign...cs.stanford.edu Abstract. Global computing involves the interplay of a vast variety of languages , but practially useful foundations for language ...framework, namely rewriting logic, that allows us to express (1) and (2) and, in addition, language aspects such as concurrency and non-determinism. We
ERIC Educational Resources Information Center
Kibbee, Douglas A. Ed.
This edited volume of conference papers contains the following titles: "Presentation: Realism and Idealism in Language Conflict and Their Resolution" (Douglas A. Kibbee); "Legal and Linguistic Perspectives on Language Legislation" (Douglas A. Kibbee); "The Linguistic Rights of Non-English Speaking Suspects, Witnesses,…
Bug Distribution and Pattern Classification.
1985-07-15
Center Educational Psychology University of Leyden San Diego. CA 92152 Urbana. IL 61801 Education Research Center oernaavelaan 2 Dr. Erling B. Andersen...Dr. Dattprasad rlivgi 23314 EN Leyden Department of Statistics Syracuse University The NETHERLANDS 3tudiestraede 6 Department of Psychology 1455...Rebecca Hetter Learning R&D Center Navy Personnel R&D Center University of Pittsburgh Ms. Kathleen Moreno Code 62 Pittsburgh, PA 15260 Navy Personnel R
ERIC Educational Resources Information Center
Henderson, Kathryn Luther, Ed.; Henderson, William T., Ed.
Papers presented at the 1981 Allerton Park Institute include: (1) "Conservation: What We should Do Until the Conservator and the Twenty-first Century Arrive," by Robert H. Patterson; (2) "Expanding Preservation Resources: The Corps of Practitioners and the Core of Knowledge," by Pamela W. Darling; (3) "National Preservation Planning and Regional…
ERIC Educational Resources Information Center
Kokhan, Kateryna
2012-01-01
The English Placement Test (EPT) at the University of Illinois at Urbana-Champaign (UIUC) is designed to provide an accurate placement (or exemption) of international students into the ESL writing and pronunciation classes. Over the last five years, UIUC has experienced an increase in the number of international students taking the EPT. Because of…
ERIC Educational Resources Information Center
DeVol, Dave
2014-01-01
When the Illinois Mathematics and Science Academy (IMSA) was founded in 1985, the state of Illinois charged IMSA with two mandates: (1) "The primary role of the Academy shall be to offer a uniquely challenging education for students talented in the areas of mathematics and science." (2) "The Academy shall also carry a responsibility…
The Perfect Career: Jennifer Hain-Teper--University of Illinois Library, Urbana-Champaign
ERIC Educational Resources Information Center
Library Journal, 2004
2004-01-01
This article details the work of Jennifer Hain-Teper, from the University of Illinois Library. For Jennifer Hain Teper, it all began with a simple question: "If you could do anything at all, regardless of pay, what would it be?" This was posed by a friend when Hain Teper was a volunteer at the wildflower research center in Austin, TX.…
Neuropsychological Component of Imagery Processing
1991-01-25
and von Bonin, G. (1951). The Isocortex of Man. Urbana, IL: University of Illinois Press. Bauer, R. M., and Rubens, A. B. (1985). Agnosia . In K. M...Apperceptive agnosia : the specification and description of constructs. In Humphreys, G. W., and Riddoch, M. J. (1987a) (Eds.). Visual Object Processing: A...visual processing: agnosias , achromatopsia, Balint’s syndrome and related difficulties of orientation and construction. In M.-M. Mesulam (Ed
Neuropsychological Components of Object Identification
1992-01-10
Man. Urbana, IL: University of Illinois Press. Bauer, R. M., and Rubens, A. B. (1985). Agnosia . In K. M. Heilman and E. Valenstein (Eds.), Clinical...J. (1987). Apperceptive agnosia : the specification and description of constructs. In Humphreys, G. W., and Riddoch, M. J. (1987a) (Eds.). Visual... agnosias , achromatopsia, Balint’s syndrome and related difficulties of orientation and construction. In M.-M. Mesulam (Ed.), Principles of Behavioral
Bombardment of Thin Lithium Films with Energetic Plasma Flows
ERIC Educational Resources Information Center
Gray, Travis Kelly
2009-01-01
The Divertor Erosion and Vapor Shielding Experiment (DEVEX) has been constructed in the Center for Plasma-Material Interactions at the University of Illinois at Urbana-Champaign. It consists of a conical theta-pinch connected to a 60 kV, 36 [mu]F capacitor bank which is switched with a rise time of 3.5 [mu]s. This results in a peak current of 300…
ERIC Educational Resources Information Center
Cochrane, Pauline Atherton, Ed.; Johnson, Eric H., Ed.
This proceedings represents and documents in part the 16 presentations made at the 34th Annual Clinic on Library Applications of Data Processing. World Wide Web URLs that provide insight into each presentation are included. Presentations include: (1) "Hypostatizing Data Collections, Especially Bibliographic: Abstractions, Representations,…
Data Sharing Interviews with Crop Sciences Faculty: Why They Share Data and How the Library Can Help
ERIC Educational Resources Information Center
Williams, Sarah C.
2013-01-01
This study was designed to generate a deeper understanding of data sharing by targeting faculty members who had already made data publicly available. During interviews, crop scientists at the University of Illinois at Urbana-Champaign were asked why they decided to share data, why they chose a data sharing method (e. g., supplementary file,…
Validation of the Noncommissioned Officer Special Assignment Battery
2013-03-01
scoring designed to reduce the effects of faking in personality assessment [ Doctoral Dissertation]. University of Illinois at Urbana-Champaign. Stark, S...conducted factor analyses to determine whether these scales could be reasonably combined to create a reduced number of criteria for examining WAI and NSAB...has been that previously validated instruments for this purpose required proctored testing. To make it easier for Soldiers to be tested, reduce
Development of Laboratory Model Ecosystems as Early Warning Elements of Environmental Pollution
1974-12-01
AD-AOll 851 DEVELOPMENT OF LABORATORY MODEL ECOSYSTEMS AS EARLY WARNING ELEMENTS OF ENVIRONMENTAL POLLUTION Robert L. Metcalf... ENVIRONMENTAL POLLUTION Robert L. Metcalf, Ph. D. University of Illinois Urbana-Champaign, Illinois INTRODUCTION Problems of environmental pollution with...house dust is unsafe to breathe (Ewing and Pearson, 1974). Most of the source of our concern about environmental pollution by trace substances relates
Georgina Santos-Barrera; Jesus Pacheco-Rodriguez
2006-01-01
Prairie-dog (Cynomys ludovicianus) colonies in northwest Chihuahua, Mexico, have been of great significance not only in initiating protection programs for the species but also in learning about the biological diversity (flora and fauna) of the natural grasslands of Janos-Casas Grandes, Chihuahua. Therefore a study of the herpetological fauna within the prairie-dog...
Exploiting Auxiliary Information about Examinees in the Estimation of Item Parameters.
1986-05-01
Research. The author is grateful to Kathleen Sheehan and Martha Stocking for their comments and suggestions. a, • ... Am -. ,** . Exploiting...Research Laboratory Dr. Hans Crombag 103 South Mathews Street University of Leyden Urbana, IL 61801 Education Research Center Boerhaavelaan 2 Dr. Susan...Embretson 23-4 EN Leyden University of Kansas The NETHERLANDS Psychology Department Lawrence, KS 66045 CTR/McGraw-Hill Library 2500 Garden Road ERIC
The Third Data Release of the Sloan Digital Sky Survey
2005-03-01
Astronomy, MSC 4500, New Mexico State University, P.O. Box 30001, Las Cruces, NM 88003. 6 Department of Astrophysical Sciences, Princeton University... Mexico Institute of Technology, 801 Leroy Place, Socorro, NM 87801. 14 Department of Astronomy, University of Illinois, 1002 West Green Street, Urbana...NJ 08544. 49 FNRS Institut d’Astronomie et d’Astrophysique, Université Libre de Bruxelles, CP. 226, Boulevard du Triomphe, B-1050 Bruxelles, Belgium
The Computer as a Tool for Learning through Reflection.
1986-03-01
different accents and backgrounds (e.g., Vanessa Redgrave, Martin Luther King, and Ricardo Montalban). Thus students can compare how they read the...Coordinated Science Laboratory Santa Barbara, CA 93106 University of Illinois Urbana, IL 61801 Edward E. Eddowes CNATRA N301 Goery Delacote Naval Air Station...DC 20052 Dr. James G. Greeno University of California Dr Jim Hollan Berkeley. CA 94720 Intelligent Systems Group Institute for Prof Edward Haertel
An Adaptive Multiscale Finite Element Method for Large Scale Simulations
2015-09-28
Illinois at Urbana-Champaign Abstract Hypersonic vehicles are subjected to extreme acoustic, thermal and mechanical loading with strong spatial and temporal...07/15/2012 Reporting Period End Date 07/14/2015 Abstract Hypersonic vehicles are subjected to extreme acoustic, thermal and mechanical loading with...gradients and for extended periods of time. Long duration, 3-D simulations of non-linear response of these vehicles , is prohibitively expensive using
Chemically Initiated Electron-Exchange Luminescence.
1980-11-14
CONTROLLING OFFICE NAME AND ADDRESS IQ. REPORT DATE Chemistry Program, raterials Science Division, November 14, 1980 Office of Naval Research, 800 N. Quincy...A./IHorn Prepared for Publication in9 z Chemi- and Bio-Energized Processes School of Chemical Sciences University of Illinois Urbana, Illinois 61801...National Science Foundation and in part by the Office of Naval Research. GBS is a Fellow of the Alfred P. Sloan Foundation (1977-79) and The Dreyfus
ERIC Educational Resources Information Center
Allen, Bryce L., Ed.; Weech, Terry L., Ed.
This is a collection of six papers on critical issues in library management presented at the annual Allerton Park Conference (35th, October 24-26, 1993) sponsored by the University of Illinois at Urbana-Champaign, Graduate School of Library and Information Science. The first paper, "Learning about Leadership: What Works in Modern Organizations"…
ERIC Educational Resources Information Center
Ramspott, Becca
2013-01-01
As one of the top U.S. choices for international students, the University of Illinois at Urbana-Champaign has a solid reputation in China and a history of educating Chinese students that goes back more than a century. But the university did not realize until last June that its nickname in China is the "Cornfield Ivy" and that Chinese…
1982-12-01
AD-A125 858 EXPERIMENTAL STUDIES OF LATERAL ELECTRON TRANSPORT IN 1/3 GALLIUM ARSENIDE-RL..(U) ILLINOIS UNIV AT URBANA COORDINATED SCIENCE LAB N R...EXPERIMENTAL STUDIES OF LATERALXILECTRON TRANSPORT ,:g IN GALLIUM ARSENIDE -ALUMINUM GALLIUM ARSENIDE- -HETEROSTRUCTURES APRVE O PUBLICRLEAS.DSRBUINULMTE. 2...EXPERIMENTAL STUDIES OF LATERAL ELECTRON TRANSPORT IN GALLIUM ARSENIDE-ALUMINUM GALLIUM ARSENIDE Technical Report R-975 HETEROSTRUCTURES 6. PERFORMING ONG
ERIC Educational Resources Information Center
Spitze, Hazel Taylor, Ed.
These conference proceedings examine the interrelationships between work life and family life and explore ways in which home economics education can contribute to the solution of attendant problems. The opening session includes a welcome and an introduction to the topic. Other papers address (1) the evolution of the role of women; (2) inflation…
NASA Technical Reports Server (NTRS)
1999-01-01
Dr. Donald Gilles, the Discipline Scientist for Materials Science in NASA's Microgravity Materials Science and Applications Department, demonstrates to Carl Dohrman a model of dendrites, the branch-like structures found in many metals and alloys. Dohrman was recently selected by the American Society for Metals International as their 1999 ASM International Foundation National Merit Scholar. The University of Illinois at Urbana-Champaign freshman recently toured NASA's materials science facilities at the Marshall Space Flight Center.
Psychometric Approach to Error Analysis on Response Patterns of Achievement Tests.
1980-02-01
Maxwell Dr. Richard L. Ferguson I Dr. Earl Hunt Department of Psychology The American Collage Testing Program Dept. of Psychology University of Houston...South Carolina Educational Testing Service Columbia. SC 29208 Princeton. NJ 08541 PROF. FiFIIKO SAMEJIMA 1 Dr. Kikumi Tatsuoka DEPT. OF PSYCHOLOGY ...Illinois Urbana Illinois PSYCHOMETRIC APPROACH TO ERROR ANALYSIS ON RESPONSE PATTERNS OF ACHIEVEMENT TESTS -.C, 0 ~KIKUMI K. TATSUOKA -’- MENUCHA
Diligence in front-end processes is critical: an interview with Cheryl A. Harmon.
Harmon, Cheryl A
2002-12-01
Cheryl Harmon's position reflects her organization's emphasis on an expanded role for the CFO. Harmon was hired recently to serve as CFO of Provena Covenant Medical Center, (PCMC) in Urbana, Illinois. Her mission as CFO is to help develop strategies to ensure that Provena Covenant maintains its financial stability. Harmon appreciates Povena Covenant's creative approaches to challenges faced by many healthcare organizations, such as workforce shortages.
ERIC Educational Resources Information Center
Kachru, Braj B., Ed.
1992-01-01
A special issue of the journal, dedicated to Henry B. Kahane, the late founder of the Department of Linguistics at the University of Illinois at Champaign, celebrates the department's first 25 years. It contains three parts. The first consists of specifically commissioned papers originally written in 1973-74 and meant for a specific project,…
Summary of Literature Describing the Functional Ability of Wetlands to Enhance Wastewater Quality
1993-08-01
may be used with these plants. Duckweed ( Lemna minor ), reed canarygrass (Phalaris arundinacea), water lily (Nymphaea sp., Nuphar sp.), and others may...sition shifted to cattail (Typha latifolia) and duck weed ( Lemna minor ), and above ground biomass increased by a factor of four. Sediment deposition in...Macrophytes: Biochemical Study And Mathematical Modelling (Artificial Wetland, Ecological Modelling, depurmodelling Dcion De Aguas Residuales Urbanas De
1999-12-01
Dr. Donald Gilles, the Discipline Scientist for Materials Science in NASA's Microgravity Materials Science and Applications Department, demonstrates to Carl Dohrman a model of dendrites, the branch-like structures found in many metals and alloys. Dohrman was recently selected by the American Society for Metals International as their 1999 ASM International Foundation National Merit Scholar. The University of Illinois at Urbana-Champaign freshman recently toured NASA's materials science facilities at the Marshall Space Flight Center.
Forth system for coherent-scatter radar data acquisition and processing
NASA Technical Reports Server (NTRS)
Rennier, A. D.; Bowhill, S. A.
1985-01-01
A real time collection system was developed for the Urbana coherent scatter radar system. The new system, designed for use with a microcomputer, has several advantages over the old system implemented with a minicomputer. The software used to collect the data is described as well as the processing software used to analyze the data. In addition a magnetic tape format for coherent scatter data exchange is given.
Supplement request for Support of MRS Symposium (PECASE: Active Microstructured Polymer Systems)
2015-07-06
materials (e.g., gels, polymers, liquids , liquid crystals and photosensitive materials) that can change shape in a controlled response to stimuli. These...Rogers1. 1, , University of Illinois, Urbana, Illinois, USA. Show Abstract 8:45 AM - *XX1.02 New Wonders of Nafion : Shape Memory, Temperature Memory... Liquid Crystal Institute, Kent State University, Kent, Ohio, USA; 5, Department of Electrical and Computer Engineering, University of Idaho, Moscow
Brain Region and Cell Type Transcripts for Informative Diagnostics
2010-09-01
cerebral cortex region, the caudoputamen region GPi, GPe CTX PIR TH CP TRS CP PVT CP PVT BST Fx CP 17 distinctly comes out. This...oligodendrocytes and astrocytes cell- specific genes (marked with white arrow in Table 5). The columns of the fornix ( Fx ) region are also clustered with...Invited talks this year: NP: Seminar, Department of Bioengineering, University of Illinois, Urbana-Champaign, IL, September 2, 2010 oligo > astro
Antimony-Based Type-II Superlattice Photodetectors
2010-09-06
photodetectors, antimony-based mid- infrared detectors Shun L. Chuang, Russell D. Dupuis University of Illinois - Urbana Grants and Contracts Office...Q. Yang, Interband Cascade Detectors , US Patent #7,282,777, October 16, 2007. Graduate Students PERCENT_SUPPORTEDNAME Shin Mou 0.25 Adam Petschke...DD882) Inventions (DD882) Interband Cascade Detectors Patent Filed in US? (5d-1) Y NPatent Filed in Foreign Countries? (5d-2) Was the assignment
Pre-Engineering Program: Science, Technology, Engineering and Mathematics (STEM)
2013-08-29
educators in the Urbana-Champaign area. 15. SUBJECT TERMS STEM: science, technology , engineering, mathematics 16. SECURITY CLASSIFICATION OF: 19a. NAME...9132T-13-1-0002 4. TITLE AND SUBTITLE Pre-Engineering Program: Science, Technology , Engineering and Mathematics (STEM) 5c. PROGRAM ELEMENT NUMBER N...project was focused on underserved children in grades 1-6 who need, but have limited access to, out-of-school time STEM (science, technology
ILLIAC IV Applications Research
1974-12-31
Reducino a Real Matrix to the Unper-Hessenbern Form," CAC Document Ko . 11: Center for Advanced Computation, Pniversitv of Illinois at Urbana...Complex for small-scale interactive imane analysis; (4) The APPA Network for decentrali7ed user access Ko t.hp system; -11- APPA FINAL REPORT (5...Grossman David M. Grothe Bruce P. Hanna Bruce M. Hannon James H. Hansen David C. Healy Steven F, Holmgren Dorothy J. Hopkin Robert J. Husby Renato
Being There is Only the Beginning: Toward More Effective Web 2.0 Use in Academic Libraries
2010-01-02
Google is Our Friend,” and “ Plagiarism 101.” Also unlike the hard-to-find blogs, many academic libraries, including both Hollins University and Urbana...Effective Web 2.0 Use in Academic Libraries by Hanna C. Bachrach Pratt Institute...5a. CONTRACT NUMBER 2.0 Use in Academic Libraries 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Bachrach
Switched Systems With Multiple Invariant Sets
2015-05-06
LaSalle’s invariant set theorem [10] allow us to analyze asymptotic stability of this larger class of systems . LaSalle’s theorem and much of the... Stability and conver- gence for systems with switching equilibria, in: Proc. of the 46th IEEE Conference on Decision and Control , 2007. [8] X. Xu, G...Champaign, Urbana, Illinois 61801 Abstract This paper explores dwell time constraints on switched systems with mul- tiple, possibly disparate
Rayleigh lidar observations of gravity wave activity in the upper stratosphere at Urbana, Ill.
NASA Technical Reports Server (NTRS)
Gardner, C. S.; Miller, M. S.; Liu, C. H.
1988-01-01
During 13 nights of Rayleigh lidar measurements at Urbana, Ill. in 1984 to 1986, thirty-six quasi-monochromatic gravity waves were observed in the 35 to 50 km altitude region of the stratosphere. The characteristics of the waves are compared with other lidar and radar measurements of gravity waves and the theoretical models of wave saturation and dissipation phenomena. The measured vertical wavelengths ranged from 2 to 11.5 km and the measured vertical phase velocities ranged from 10 to 85 cm/s. The vertical wavelengths and vertical phase velocities were used to infer observed wave periods which ranged from 100 to 1000 min and horizontal wavelengths which ranged from 70 to 2000 km. Dominant wave activity was found at vertical wavelengths between 2 to 4 km and 7 to 10 km. No significant seasonal variations were evident in the observed parameters. Vertical and horizontal wavelengths showed a clear tendency to increase with wave periods, which is consistent with recent sodium lidar studies of quasi-monochromatic waves near the mesopause. An average amplitude growth length of 20.9 km for the rms wind perturbations was estimated from the data. Kinetic energy density associated with the waves decreased with height, suggesting that waves in this altitude region were subject to dissipation or saturation effects.
Intrinsic Charge Transport in Organic Field-Effect Transistors
NASA Astrophysics Data System (ADS)
Podzorov, Vitaly
2005-03-01
Organic field-effect transistors (OFETs) are essential components of modern electronics. Despite the rapid progress of organic electronics, understanding of fundamental aspects of the charge transport in organic devices is still lacking. Recently, the OFETs based on highly ordered organic crystals have been fabricated with innovative techniques that preserve the high quality of single-crystal organic surfaces. This technological progress facilitated the study of transport mechanisms in organic semiconductors [1-4]. It has been demonstrated that the intrinsic polaronic transport, not dominated by disorder, with a remarkably high mobility of ``holes'' μ = 20 cm^2/Vs can be achieved in these devices at room temperature [4]. The signatures of the intrinsic polaronic transport are the anisotropy of the carrier mobility and an increase of μ with cooling. These and other aspects of the charge transport in organic single-crystal FETs will be discussed. Co-authors are Etienne Menard, University of Illinois at Urbana Champaign; Valery Kiryukhin, Rutgers University; John Rogers, University of Illinois at Urbana Champaign; Michael Gershenson, Rutgers University. [1] V. Podzorov et al., Appl. Phys. Lett. 82, 1739 (2003); ibid. 83, 3504 (2003). [2] V. C. Sundar et al., Science 303, 1644 (2004). [3] R. W. I. de Boer et al., Phys. Stat. Sol. (a) 201, 1302 (2004). [4] V. Podzorov et al., Phys. Rev. Lett. 93, 086602 (2004).
Study of 11Li+p elastic scattering using BHF formalism with three body force
NASA Astrophysics Data System (ADS)
Sharma, Manjari; Haider, W.
2018-04-01
In the present work we have analyzed the elastic scattering data of 11Li + p at 62, 68.4 and 75 MeV/nucleon, using the microscopic optical potential calculated within the framework of Brueckner-Hartree-Fock formalism (BHF). The calculation uses Argonne v18 and Urbana v14 inter-nucleon potentials and the Urbana IX (UVIX) model of three body force. The required nucleon-density distributions for 11Li are obtained using the semi-phenomenological model for nuclear density distributions. The optical potential has been obtained by folding the g-matrices as calculated in BHF (with and without three body forces) over the nucleon density distributions. We have used the exact method for calculating both the direct and the exchange parts of the spin-orbit potential. Our results reveal that the spin-orbit potential significantly contributes to 11Li+p elastic scattering at all three incident energies. Further, the calculated spin-orbit potential in BHF is much smaller and more diffused as compared with the phenomenological spin-orbit potential. The analysis reveals that the calculated microscopic optical potentials, with and without three body force using BHF approach with phenomenological form of density distribution, provides satisfactory agreement with the elastic scattering data for 11Li+p.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cooper, T.C.
A visit was made to the Frit Bagging Operation at the Chi-Vit Corporation located at Urbana, Ohio for the purpose of examining methods used at this facility to control worker exposure to hazardous materials during the production of various frits. Frit was the basic material for porcelain enamel used in major appliance finishes. The three major raw materials used to produce frit were soda-ash, borax, and silica-flour. In the manufacturing area batching, mixing, smelting, and bagging take place. All new employees were given a preemployment physical. An annual hearing evaluation was performed for all workers. Ventilation was provided throughout themore » operation. Each weight bin in the batching area was equipped with exhaust ventilation. The frit was moved by a vibration conveyor between smelter and bagger and passed under three exhaust hoods to remove airborne dust during this last portion of this transfer. A small capture hood at the packer unit removed airborne dust generated as material falls from the slide gate to the packer spout. The disposal of the bags was carried out in a very satisfactory manner. The author concludes that the controls used provided an exemplary work environment. The author recommends that an in-depth survey be conducted at this site.« less
Diversidad de Sistemas Planetarios en Discos de Baja Masa
NASA Astrophysics Data System (ADS)
Ronco, M. P.; de Elía, G. C.
The accretion process that allows the formation of terrestrial planets is strongly dependent on the mass distribution in the system and the presence of gas giant planets. Several studies suggest that planetary systems formed only by terrestrial planets are the most common in the Universe. In this work we study the diversity of planetary systems that could form around solar-type stars in low mass disks in absence of gas giants planets and search wich ones are targets of particular interest. FULL TEXT IN SPANISH
Sharing to Succeed: Lessons from Open Information-sharing Projects in Afghanistan
2013-07-01
initiative. rebecca linder Blachly is di- rector of advancement, international Programs, and Studies at the univer- sity of illinois at urbana...learned. July 2013 by Linton Wells II, James Bosworth, John Crowley, and Rebecca Linder Blachly Report Documentation Page Form ApprovedOMB No. 0704-0188...been de - veloping personal relationships early with actors who are www.ndu.edu/inss dh No. 76 5 seen as working in the local community’s best
ERIC Educational Resources Information Center
Lancaster, F. W., Ed.; Smith, Linda C., Ed.
Some of the 12 conference papers presented in this proceedings focus on the present and potential capabilities of artificial intelligence and expert systems as they relate to a wide range of library applications, including descriptive cataloging, technical services, collection development, subject indexing, reference services, database searching,…
ERIC Educational Resources Information Center
Harum, Susan, Ed.; Twidale, Michael, Ed.
This clinic's goal was to address questions arising during the process of transition from theory and research development to deployed useful and usable (and used) digital library systems. The idea was to use the Digital Libraries Initiative (DLI) based at the University of Illinois at Urbana-Champaign and entering its final year, as a detailed…
Potential Improvements for HEC-HMS Automated Parameter Estimation
2006-08-01
and is now a graduate student in the Department of Civil and Environmental Engineering at the University of Illinois at Urbana /Champaign. Daniel...divided into 14 nested subwatersheds with a flow measuring flume constructed at each of the subwatershed outlets. The drainage areas above the...boundaries and stream network, and rain and stream gauge locations are shown in Figure 1. The first HEC-HMS model was applied to the 39.8-acre drainage
1983-01-01
Springfield Ave. Urbana. IL 61801 11. CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE January 1983 13. NUMBER OF PAGES 163 14. MONITORING AGENCY NAME...AOORESS(II different from Controlling Office) IS. SECURITY CLASS. (of this report) IUnclassified ISa. DECLASSIFICATION OOWNGRADING 16. OIST IUTIO...understood and quantitatively calculated by the same approach: A Monte Carlo simulation inclu g a pseudopotential band structure. The Monte Carlo simulation
1975-08-15
Heckscher T. F. Deutsch H. Kildal D. L. Spears I. Melngailis T. C. Haiman P. L. Kelley R. S. Eng D. L. Spears H. R. Fetterman H. R... Fetterman H. R. Schlossberg* W. E. Barch 1975 International IEEE/APS Symposium and USNC/URSI Meeting, Urbana, Illinois, 4 June 1975 * Author not...ft. Chinn, S. R. Del-eo, ft. E. Deutsch, T. F. Fetterman , II. R. Hancock, R. C. II. Ileckscher, Kildal, II. Larsen, D. M. Mandel, P
Glycemic control strategies and the occurrence of surgical site infection: a systematic review.
Domingos, Caroline Maria Herrero; Iida, Luciana Inaba Senyer; Poveda, Vanessa de Brito
2016-01-01
To analyze the evidence available in the scientific literature regarding the relationship between the glycemic control strategies used and the occurrence of surgical site infection in adult patients undergoing surgery. This is a systematic review performed through search on the databases of CINAHL, MEDLINE, LILACS, Cochrane Database of Systematic Reviews and EMBASE. Eight randomized controlled trials were selected. Despite the diversity of tested interventions, studies agree that glycemic control is essential to reduce rates of surgical site infection, and should be maintained between 80 and 120 mg/dL during the perioperative period. Compared to other strategies, insulin continuous infusion during surgery was the most tested and seems to get better results in reducing rates of surgical site infection and achieving success in glycemic control. Tight glycemic control during the perioperative period benefits the recovery of surgical patients, and the role of the nursing team is key for the successful implementation of the measure. Analisar as evidências disponíveis na literatura científica sobre a relação entre as estratégias de controle glicêmico efetuadas e a ocorrência de infecção do sítio cirúrgico em pacientes adultos submetidos à cirurgia. Trata-se de revisão sistemática, por meio das bases de dados CINAHL, MEDLINE, LILACS, Cochrane Database of Systematic Reviews e EMBASE. Foram selecionados oito ensaios clínicos randomizados. Apesar da diversidade de intervenções testadas, os estudos concordam que o controle glicêmico é essencial para a redução das taxas de infecção do sítio cirúrgico e deve ser mantido entre 80 e 120 mg/dL durante o perioperatório. A infusão contínua de insulina no transoperatório foi a mais testada e parece obter melhores resultados na redução das taxas de infecção do sítio cirúrgico e sucesso no controle glicêmico comparada às demais estratégias. O controle glicêmico rigoroso durante o perioperatório beneficia a recuperação do paciente cirúrgico, destacando-se a atuação da equipe de enfermagem para a implantação bem-sucedida da medida.
ERIC Educational Resources Information Center
Shaw, Debora, Ed.
This collection explores the human aspect of the automation and reautomation of library functions as both library staff and library users are expected to adapt to and use computers. A brief introduction by Debora Shaw sets the stage for the following papers: (1) "Terminal Paralysis, or Showdown at the Interface" (Sara Fine); (2)…
1988-03-01
February 1986. Kotler , Philip , Bobby J. Calder, Brian Sternthal, and Alice Tybout. "A Marketing Approach to the Development and Dissemination of...intended to cause a particular acquirer, or class of acquirers, to initiate a transfer. In the business world, this operation is called marketing . The... marketing operation and the transfer operation make up the active mode of technology transfer. When operating in the *active mode, the providing
Toxicologic and Analytical Studies with T-2 and Related Trichothecene Mycotoxins
1985-08-20
Diagnostic Lab, Urbana, IL ’ Modulus anesthetic machinf with Vernitrol vaporizer, Ohio Med Prod, Madison , WI Bird Mark 4A ventilator, 3M Corp., Minneapolis...advanced into the lumbar region of the descending’ Aorta via the right femoral artery. These catheters were then heparinized to maintain patency and the...over the caudal lumbar region (Fig. 1). In addition, the limbs are hobbled to decrease their range of nmction and minimize the possibility of injury
Application of Component Scoring to a Complicated Cognitive Domain
1985-05-15
Command (N-5) NAS Pensacola, FL 32508 Dr. John M. Eddins S..""*University of IllinoisDr. Hans Crombag 252 Engineering Research University of Leyden ...Laboratory Education Research Center 103 South Mathews Street Boerhaavelaan 2 Urbana, IL 61801 2334 EN Leyden The NETHERLANDS V.- University of Illinois...Naval Air Station Pensacola, FL 32508 Ms. Kathleen Moreno Navy Personnel R&D Center Dr. Gary Marco Code 62 Stop 31-E San Diego, CA 92152 Educational
Deflagration to Shock to Detonation Transition of Energetic Propellants.
1984-07-01
Champaign Urbana, IL 61801 Prepared for: Air Force Office of Scientific Research Aerospace Sciences Directorate: Bldg. 410 Boiling Air Force Base, DC 20332...Program Manager: Dr. Henry R. Radoski For Research Performed under ()Grant AFOSR 81-0145 During Period I June 1983 through 30 May 1984 AIR ,,1 C~i...ADDRESS 12. REPORT DATE / Air Force Office of Scientific Research/Q July 1984 Building 410; ATTN: Henry R. Radoski 13. NUMBER OF AGES Bolling Air Force
Study of Antenna Radome Problems
1981-04-01
115 DISTRIBUTION LIST .... ......................... 117 4 - #iE MU aM . a--. LIST 01 FICURZS Figure Page 1. Antenna A end radoe E...coetficiente at points 1 and 2 (Figure 26a) T -T n1E + (1/0) (5.18) In a sitmitar manner, we can calculate the field on the multiply refracted rays (t. twice...34 Differential geometry for GTD applications," ElectromagneticsLaboratory Report 77-21, University of Illinois, Urbana, IL, 1977. (lij F. W. Sears, M. W
Symposium on Animal Retroviruses: Abstracts. Held in Denver, Colorado on 10 December 1986
1986-12-10
Ogilvie, M. B. Tompkins, W. A. F. Tompkins and S. Daniel, University of Illinois, Urbana, IL. 3:15 Coffee Break 3:45 MOLECULAR BIOLOGY OF BOVINE ...secretion, or by altering cell functions through cell surface receptors. MOLECULAR BIOLOGY OF BOVINE LEUKEMIA VIRUS. A. Burny, Y. Cleuter, R. Kettmann, M...Mammerickx, G. Marbaix, D. Portetelle, A. Van Den Broeke and L. Willems, University of Brussels, Rhode-Saint-Genese, Belgium. Bovine leukemia virus (BLV
American Military Ethics: Stalwart in a Changing Society
2011-05-19
73 Raymond B. Lech , Broken Soldiers (Urbana, IL: University of Illinois Press, 2000), 215. 74 Gaddis, The Landscape of History, 4. 75 Edwards, The...communist 78 Ibid., 167. 79 Ibid., 168. Korea saw ten times the POW deaths then World War II. 80 Lech , Broken Soldiers, 2. 81 John A. Lynn, Battle...1953; April 24, 1953; April 29, 1953; August 10, 1953; August 16, 1953; August 20, 1953. 83 Lech , Broken Soldiers, 298. 84 Richard A. Gabriel, To
Effects of Strong Local Sporadic E on ELF Propagation.
1978-08-15
Huygens diffraction model (e.g., Marcuse , 1972). The model is similar to that used by Crombie. Unlike Crombie’s work however , the Fresnel approximation...40. Marcuse , D., “Light transmission optics ,” Van Nostrand Reinhold Co., New York , 1972. Papper t , R. A. & Moler , W. F., “A theoretica’ study of...ATTN Donald Dubbert O1 CY ATTN Herbert Rend University of IllinoisDepartment of Electrical Engineering Develco Urbana , IL 61803 530 Logue Avenue O2CY
The Bat Tick Carios Azteci (Acari: Argasidae) From Belize, With An Endosymbiotic Coxiellaceae
2016-12-01
ADDRESS(ES) USAF School of Aerospace Medicine Aeromedical Research Dept/FHT 2510 Fifth St., Bldg. 840 Wright-Patterson AFB, OH 45433-7913 8...Durden2, Elizabeth H. Foley3 & Will K. Reeves4 1Illinois Natural History Survey, Prairie Research Institute, University of Illinois at Urbana...the taxonomic level. Further research into the pathogens and diversity of bat parasites and diseases is an open field of research in the tropics. Some
Progress Report for Grant Number W911NF-09-1-0347 (University of Illinois - Urbana)
2012-11-06
critical tunneling current is proportional to mexc, we find good agreement with this explanation via the approximate square-root dependence seen in Fig...can occur near the contact, reducing interlayer conductivity significantly. As critical tunneling current is linearly dependent on the width of the...studied the possibility of finding the same type of condensation in a 3D topological insulator, and started our work on a time- dependent theory to
Proceedings of the 1985 Antenna Applications Symposium. Volume 2.
1985-12-01
in reflector antenna systems. In the first, -. suppression of a high power mobile S-band source was accomplished while maintaining a continuous link...substrates. Ph.D. thesis . University of Illinois at Urbana- Champaign. [71 Harrington. R+F. (1961) Tinze-farmo~ntc Electromnagn~etic Fields, McGraw-Hill. New...to be adequate for the 102’ range spacing. From this analysis, and the weight limitation of the mobile tower, a non-backplaned array with non-resonant
1987-02-01
apply here. The primary negative effect of the inclusion of test ports into the package is to increase its size and complexity. In summary, the...FORCE SYSTEMS COMMAND APPROVED FOR PUBLIC RELEMSE DISTRIBUTION UNLIMITED .i ROME AIR DEVELOPMENT CENTER Air Force Systems Command Griffiss Air Force...ORGANIZATION b. OPFICE SYMBOL 7&. NAME OP MONITORING OAGANIZATION 10I11110111blep Rome Air Development Center EEMA 4116 A00101163 (City. Sfte *Ad ZIP C4,40
1992-11-01
total-energy calculations that this complex mechanism for diffusion can be invoked for surface self-diffusion on the (100) surface ( Kellog and...Woodland Hills, CA 91364 National Science Foundation 3 SRI International ATIN: A.B. Harvey ATIN: G. Smith Washington, DC 20550 D. Crosley D. Golden...Aeronautics and Astronautics ATTN: H. Krier ATfN: J.R. Osborn 144MEB, 1206 W. Green St. Grissom Hall Urbana, IL 61801 West Lafayette, IN 47906 The Johns
ERIC Educational Resources Information Center
Lopez, Maria I. Hernandez; And Others
In 1962 and again in 1965, a group of sixth and ninth grade students in selected schools in four Puerto Rican communities were interviewed to investigate the factors influencing students' decision to withdraw from school before completing twelfth grade and to identify some characteristics of dropouts. Of 616 students interviewed in 1962, 20.9% of…
Army Installations Water Sustainability Assessment: An Evaluation of Vulnerability to Water Supply
2009-09-01
del Norte Water Task Force PM particulate matter PNNL Pacific Northwest National Laboratory PWC Public Works Commission PWD RFTA RSC Regional...ct io n E n gi n ee ri n g R es ea rc h L ab or at or y Approved for public release; distribution is unlimited. ERDC/CERL TR-09-38...and Ryan Holmes University of Illinois at Urbana-Champaign Final Report Approved for public release; distribution is unlimited. Prepared for U.S
Low-Level Convergence and the Prediction of Convective Precipitation in South Florida.
1981-02-01
Af" -Ao97 55 ILLINOIS STATE WATER SURVEY URBANA F/6 4/2 LOWLEVEL CONVERGENCE AND THE PREDICTION OF CONVECTIVE PRECIPIT-ETC(U) FEB 81 A I WATSON. R L...varying meteorological cond’tions and ti: == UNCLASSIFIED of day. SECURITY CLASSIFICATIOR OF TNIS PAGE (Whven Data Etered) State Water Survey...1981 1: 4. i0 The project "Low-level Convergence and the Prediction of Convective Precipitation" is a coordinated research effort by the State Water
A DoD/DESAT Phase I Final Report,
1982-06-30
19-22, 1982 in Albuquerque, New Mexico: 1) Spatially Correlated Redistribution of Mn and Ge in Inl.x Gax As MBE layers, E. Silberg , T.Y. Chang, and...Urbana-Champaign. 2) Spatially correlated redistribution of Mn and Ge in InGaAs MBE layers in conjunction with E. Silberg , T.Y. Chang and E.A. Caridi at...AlGaAs MBE layers. 2) A group headed by Ors. T. Chang and E. Silberg of Bell Laboratories in Holmdel, New Jersey, have been involved in growing Mn and
1990-06-30
since the projected ion range is of the order of lattice constants. Thus, we have extended our thermal-dopant incorporation model and have developed...bombardment results in residual lattice damage, which degrades electrical and optical properties. Obviously, at sufficiently high acceleration energies...understand the details of collisional lattice dynamics and ion-induced defect for- mation and annihilation. In addition, the simulations are providing, for
Environmental Impact Statement. Disposal and Reuse of Chanute Air Force Base, Illinois
1991-07-01
lines characteristic of the Midwest . The nearest major urban area is Champaign-Urbana, 15 miles south of Rantoul (see Figure 3.2-1). Village of Rantoul...and 70 tons per day during the summer. Coal Is delivered by truck from southern Indiana . The second heating plant is in Building 998, In the southeast...grasses, trees, and shrubs have been used for landscaping the base. Trees have been planted along streets and walkways as well as in lawns, and shrubs
1985-03-01
Order Perturbation Theory for Assessment" Authors: James T. hlaber. Asok Ray , A. B. Kunz and R. Weidman Place: Eight Canadian Symposium on Theoreticai...Urbana, I 61801 ASOK K. RAY * and ROBERT WEIDMAN Physics Department, Michigan Technological University Houghton, MI 49931 and JAMES T. WABER Department...PERTURBATION THEORY FOR ASSESSMENT by James T. Waber NorthNestern University, Evanston ZL 60201 Asok Ray University of Texas at Arlington, Arlington TX 76019 A
2008-12-21
celled Nitinol has recently become possiblevia a (newly discovered by Profs. D. Grummon at Michigan State Univ. and J.Shaw at Univ. of Michigan...transient-liquid reactive brazing system for creating robust metallurgical Nitinol Nitinol bonds. With this technique, prototype sparse cellularhoneycomb...Brian.Berg@bsci.com Nitinol has become a frequently used medical implant material despite its notorious complexity; especiallywith respect to fatigue [1
2007-02-15
fibre interaction are areas that require further research. Experimental and modelling studies undertaken at UIUC on individual microcapsules have many... Microcapsules : Work at UIUC has shown microcapsules to be a very effective method of self- healing to recover fracture toughness. In particular... microcapsule , cleaving it and initiating the release of monomer. A potential limitation of the microcapsule system is the limited volume of self-healing
1983-01-01
1980 (this conference) attests to method , that in admittedly a phased b array context, and to method being a bit complex. Polarization control...Computation of the phase shift was made by two methods . The first used equations in Marcuvitz 4 for an E-plane waveguide bend, with changes in e i...made by adjustment of the waveguide width. The second method (Bahar-) requi-edi solving the wave equation in cylindrical coordinates. 28 Because the
Crenshaw, Tanya L.; Chambers, Erin W.; Heeren, Cinda; Metcalf, Heather E.
2017-01-01
Just over 10 years ago, we conducted a culture study of the Computer Science Department at the flagship University of Illinois at Urbana-Champaign, one of the top five computing departments in the country. The study found that while the department placed an emphasis on research, it did so in a way that, in conjunction with a lack of communication and transparency, devalued teaching and mentoring, and negatively impacted the professional development, education, and sense of belonging of the students. As one part of a multi-phase case study spanning over a decade, this manuscript presents preliminary findings from our latest work at the university. We detail early comparisons between data gathered at the Department of Computer Science at the University of Illinois at Urbana-Champaign in 2005 and our most recent pilot case study, a follow-up research project completed in 2016. Though we have not yet completed the full data collection, we find it worthwhile to reflect on the pilot case study data we have collected thus far. Our data reveals improvements in the perceptions of undergraduate teaching quality and undergraduate peer mentoring networks. However, we also found evidence of continuing feelings of isolation, incidents of bias, policy opacity, and uneven policy implementation that are areas of concern, particularly with respect to historically underrepresented groups. We discuss these preliminary follow-up findings, offer research and methodological reflections, and share next steps for applied research that aims to create positive cultural change in computing. PMID:28579969
M. Torrez; W. Arendt; J. M. Maes
2013-01-01
Para evaluar la diversidad de aves y mariposas ninfálidas visitamos la Estación Biológica Juan Roberto Zarruk en Jinotega, donde colectamos datos en todos los hábitats presentes en la finca. Obtuvimos 123 especies de aves y 29 especies de ninfálidos. El hábitat con mayor riqueza para aves fue el cafetal y para ninfálidos el tacotal. Entre las especies más comunes...
Analyzing Infrequent Events: Once You Find Them Your Troubles Begin.
1980-04-01
e €ical kepmt. 80-3 /J,, p r - ...... Running Head: Analyzing Infrequent Events -_ Prepared with the support of the Organizatio-Effec-Uanasa Research...of post hoc groups defines after the occurrences of the event - , 1473 ,FI ,, o , ov 5 IS 0:, l.FTr , • . IS i N , { I , ; 0 1 4 - 0& E ct U m I r Y...AA8 048 ILLINOIS WdIV AT URBANA-CHAMPAIGN DEPT OP PSYCHOLOGY F/B 5/10 ANALYZING INFREQUENT EVENTS: ONCE YOU FIND THEN YOUR TROUBLES B-ETC(U) APR 80 C
A preprocessor for the Urbana coherent-scatter radar
NASA Technical Reports Server (NTRS)
Zendt, F. T.; Bowhill, S. A.
1982-01-01
The design, interfacing, testing, and operation of a preprocessor to increase the altitude and temporal resolution of the present coherent-scatter system are described. This system upgrade requires an increase in the data collection rate. Replacing the present, relatively slow, ADC with two high speed ADCs achieves the increased echo sampling rate desired. To stay within the capabilities of the main computer's I/O and processing rate the data must be reduced before transfer to the main computer. Thus the preprocessor also coherently integrates the data before transfer.
2012-07-01
population. The amount of information on Facebook doubles every 6 months. This under- scores the nation’s need to understand what is happening on a ...QL—Russia: Emerging Insight Into Muslim Populations (October 2011) • QL— A Trend Toward Increased Information Communication Technol- ogy (ICT...Hendrix ( College of William & Mary), Mr. Eric A . Knudson (PACOM), Mr. Joseph T. Lee (PACOM), Mr. Kalev Leetaru (University of Illinois at Urbana), Lt
NASA Technical Reports Server (NTRS)
Green, J. L.; Gage, K. S.; Vanzandt, T. E.; Nastrom, G. D.
1986-01-01
A flexible very high frequency (VHF) stratosphere-troposphere (ST) radar configured for meteorological research is to be constructed near Urbana, Illinois. Measurement of small vertical velocities associated with synoptic-scale meteorology can be performed. A large Doppler microwave radar (CHILL) is located a few km from the site of the proposed ST radar. Since the microwave radar can measure the location and velocity of hydrometeors and the VHF ST radar can measure clear (or cloudy) air velocities, simultaneous observations by these two radars of stratiform or convective weather systems would provide valuable meteorological information.
Acute Respiratory Tract Toxicity of the Trichothecene Mycotoxin, T-2 Toxin.
1987-03-31
to 10-week-old, castrated , e male, cross-bred, specific pathogen-free pigs were exposed to an aerosol of T-2 toxin for 45 to 61 minutes with 8 mg of... castrated , crossbred, specific pathogen-free swine to aerosols of T-2 toxin for 42 to 65 minutes with 9 mg of the toxin nebulized per kilogram of body... cattle , Ph.D. Thesis, University of Illinois, Urbana, IL, 1983. 28. Lorenzana, R.M., Beasley, V.R., Buck, W.B., Ghent, A.W., Lundeen, G.R., and
1991-06-30
AND TITLES: 0. Arikan , Research Assistant I W. Chuang, Research Assistant A. Krone, Research Assistant M, Leung, Research Assistant I Y. Liu, Research...P. Willis and Y. Bresler, "Norm invariance of minimax-optimal interpolation," submitted to3 IEEE Trans. Inform. Theory. (JSEP/NSF) [5] 0. Arikan and...imaging of time varying distributions," in Proc. Int. Syrup. Circuits and Syst., Singapore, Jun. 1991 (to appear). (JSEP/NSF) [101 0. Arikan and 1). C
1981-09-01
reflectivity near 9.0 GHz and relative transparency above 10.5 GHz and below 7.5 GHz. The frequency-selective response of the FSS, as tested in the...FREQUENCY (GHz) Figure 6. Frequency Selective Responses of FSS U.~I noU 0 .jj 7 41 IN J43 cH-’ AI 4c!,) ---------- -- ,-7 -7 2Z~Zf -~44 -- t 4qpi V...assumes no responsibility for the information presented." -2- quiescent (before adaption) radiation pattern of the adaptive antenna affects the initial
The Urbana coherent-scatter radar: Synthesis and first results
NASA Technical Reports Server (NTRS)
Gibbs, K. P.; Bowhill, S. A.
1979-01-01
A coherent scatter radar system was synthesized and several hundred hours of echo power and line of sight velocity data obtained. The coherent scatter radar utilizes a diode array and components from meteor radar. The receiving system permits a time resolution of one minute in the data. Echo power from the D region shows a high degree of variability from day to day. Examples of changes in power level at shorter time scales are observed. Velocity data show the existence of gravity waves and occasionally exhibit vertical standing wave characteristics.
ERIC Educational Resources Information Center
Tedesco, Juan Carlos
Forty percent of the families in Latin America have an income which does not provide essential necessities. Two-thirds of poor families live in the countryside, while the remainder reside in urban slums. The key variable in explaining poverty is education. Without education these families have irregular, unstable, and low paying employment…
NASA Technical Reports Server (NTRS)
Loane, J. T.; Bowhill, S. A.; Mayes, P. E.
1982-01-01
The effects of atmospheric turbulence and the basis for the coherent scatter radar techniques are discussed. The reasons are given for upgrading the Radar system to a larger steerable array. Phase array theory pertinent to the system design is reviewed, along with approximations for maximum directive gain and blind angles due to mutual coupling. The methods and construction techniques employed in the UHF model study are explained. The antenna range is described, with a block diagram for the mode of operation used.
Koltun, G.F.
1995-01-01
This report describes the results of a study to estimate characteristics of base flow and sustained ground-water discharge at five streamflow-gaging stations on the Mad River in Ohio. The five streamflow-gaging stations are located at Zanesfield, near Urbana, at St. Paris Pike (at Eagle City), near Springfield, and near Dayton. The median of the annual-mean base flows, determined by means of hydrograph separation, ranged from 0.64 (ft3/s)/mi2 (cubic feet per second per square mile) at Zanesfield to 0.74 (ft3/s)/mi2 at St. Paris Pike. The median percentage of annual total streamflow attributed to base flow ranged from 61.8 percent at Zanesfield to 76.1 percent near Urbana. Estimates of an upper limit (or threshold) at which base flows can be considered to be composed predominately of sustained ground-water discharge were made by constructing and analyzing base- flow-duration curves. The sustained ground-water discharges (base flows less than or equal to the estimated sustained ground-water-discharge thresholds) are assumed to originate from ground-water- flow systems that are minimally affected by seasonal climatic changes. The median sustained ground- water discharge ranged from 0.11 (ft3/s)/mi2 at Zanesfield to 0.26 (ft3/s)/mi2 at St. Paris Pike (at Eagle City) and near Springfield. The median sustained ground-water discharge, expressed as a percentage of the median annual-mean base flow, ranged from 17.2 percent at Zanesfield to 38.6 percent near Springfield.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, M.M.; Chao, B.T.
This technical progress report covers the progress made during the fifth quarter of the project entitled Measurements of Solids Motion in Gas Fluidized Beds under Grant No. DOE-F22-81PC40804 during the period 1 October through 31 December 1982. The research concerns the measurement of solids particle velocity distribution and residence time distribution using the Computer-Aided Particle Tracking Facility (CAPTF) at the University of Illinois at Urbana-Champaign. The experimental equipment and measuring methods used to determine particle size distribution and particle motion and the results obtained are presented.
Perturbation theory of nuclear matter with a microscopic effective interaction
DOE Office of Scientific and Technical Information (OSTI.GOV)
Benhar, Omar; Lovato, Alessandro
Here, an updated and improved version of the effective interaction based on the Argonne-Urbana nuclear Hamiltonian, derived using the formalism of correlated basis functions and the cluster expansion technique, is employed to obtain a number of properties of cold nuclear matter at arbitrary neutron excess within the formalism of many-body perturbation theory. The numerical results, including the ground-state energy per nucleon, the symmetry energy, the pressure, the compressibility, and the single-particle spectrum, are discussed in the context of the available empirical information, obtained from measured nuclear properties and heavy-ion collisions.
Perturbation theory of nuclear matter with a microscopic effective interaction
Benhar, Omar; Lovato, Alessandro
2017-11-01
Here, an updated and improved version of the effective interaction based on the Argonne-Urbana nuclear Hamiltonian, derived using the formalism of correlated basis functions and the cluster expansion technique, is employed to obtain a number of properties of cold nuclear matter at arbitrary neutron excess within the formalism of many-body perturbation theory. The numerical results, including the ground-state energy per nucleon, the symmetry energy, the pressure, the compressibility, and the single-particle spectrum, are discussed in the context of the available empirical information, obtained from measured nuclear properties and heavy-ion collisions.
NASA Astrophysics Data System (ADS)
Zhang, Hongmei; Wang, Yue; Fatemi, Mostafa; Insana, Michael F.
2017-03-01
Kelvin-Voigt fractional derivative (KVFD) model parameters have been used to describe viscoelastic properties of soft tissues. However, translating model parameters into a concise set of intrinsic mechanical properties related to tissue composition and structure remains challenging. This paper begins by exploring these relationships using a biphasic emulsion materials with known composition. Mechanical properties are measured by analyzing data from two indentation techniques—ramp-stress relaxation and load-unload hysteresis tests. Material composition is predictably correlated with viscoelastic model parameters. Model parameters estimated from the tests reveal that elastic modulus E 0 closely approximates the shear modulus for pure gelatin. Fractional-order parameter α and time constant τ vary monotonically with the volume fraction of the material’s fluid component. α characterizes medium fluidity and the rate of energy dissipation, and τ is a viscous time constant. Numerical simulations suggest that the viscous coefficient η is proportional to the energy lost during quasi-static force-displacement cycles, E A . The slope of E A versus η is determined by α and the applied indentation ramp time T r. Experimental measurements from phantom and ex vivo liver data show close agreement with theoretical predictions of the η -{{E}A} relation. The relative error is less than 20% for emulsions 22% for liver. We find that KVFD model parameters form a concise features space for biphasic medium characterization that described time-varying mechanical properties. The experimental work was carried out at the Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Methodological development, including numerical simulation and all data analysis, were carried out at the school of Life Science and Technology, Xi’an JiaoTong University, 710049, China.
New Editors Appointed for Water Resources Research
NASA Astrophysics Data System (ADS)
2009-03-01
Praveen Kumar (University of Illinois at Urbana-Champaign), the newly appointed editor in chief of Water Resources Research (WRR), heads the new team of editors for the journal. The other editors are Tom Torgersen (University of Connecticut, Groton), who continues his editorship; Tissa Illangasekare (Colorado School of Mines, Golden); Graham Sander (Loughborough University, Loughborough, UK); and John Selker (Oregon State University, Corvallis). Hoshin Gupta (University of Arizona, Tucson) will join WRR at the end of 2009. The new editors will begin receiving submissions immediately. The incoming editorial board thanks outgoing editors Marc Parlange, Brian Berkowitz, Amilcare Porporato, and Scott Tyler, all of whom will assist during the transition.
1987-02-01
J.R. Pickens Dept. of Metallurgy & Mining Eng. Martin Marietta Laboratories % University of Illinois 1450 South Rolling Rd. Urbana, EIl 61801...AND MINERAL DEPARTMENT OF MATERIALS SCIENCE SCIENCES METALLURGY PROGRAM 00 00 TECHNICAL REPORT February 1987 OFFICE OF NAVAL RESEARCH IContract No...725 % ~ ~ ’. -~ ~AS~~jX.%......... !1CUlnITY CLASSIFICATION OF THIS PAGE (When n#e& Entered) REPORT DOCUMENTATION PAGE READ INSTRUCTIONS
An accelerated forth data-acquisition system
NASA Technical Reports Server (NTRS)
Bowhill, S. A.; Rennier, A. D.
1986-01-01
A new data acquisition system was put into operation at Urbana in August 1984. It uses a standard Apple 2 microcomputer with 48 k RAM and a standard 5 1/4 inch floppy disk. Design criteria for the system is given. The system was implemented using fig-FORTH, a threaded interpretive language which permits easy interfacing to machine code. The throughput of this system is better by a factor of 6 than the PDP-15 minicomputer system previously used, and it has the real time display feature and provides the data in much more convenient form. The features which contribute to this improved performance is listed.
Bryant-Lukosius, Denise; Valaitis, Ruta; Martin-Misener, Ruth; Donald, Faith; Peña, Laura Morán; Brousseau, Linda
2017-01-30
to examine advanced practice nursing (APN) roles internationally to inform role development in Latin America and the Caribbean to support universal health coverage and universal access to health. we examined literature related to APN roles, their global deployment, and APN effectiveness in relation to universal health coverage and access to health. given evidence of their effectiveness in many countries, APN roles are ideally suited as part of a primary health care workforce strategy in Latin America to enhance universal health coverage and access to health. Brazil, Chile, Colombia, and Mexico are well positioned to build this workforce. Role implementation barriers include lack of role clarity, legislation/regulation, education, funding, and physician resistance. Strong nursing leadership to align APN roles with policy priorities, and to work in partnership with primary care providers and policy makers is needed for successful role implementation. given the diversity of contexts across nations, it is important to systematically assess country and population health needs to introduce the most appropriate complement and mix of APN roles and inform implementation. Successful APN role introduction in Latin America and the Caribbean could provide a roadmap for similar roles in other low/middle income countries. analisar o papel da enfermagem com prática avançada (EPA) a nível internacional para um relatório do seu desenvolvimento na América Latina e no Caribe, para apoiar a cobertura universal de saúde e o acesso universal à saúde. análise da bibliografia relacionada com os papéis da EPA, sua implantação no mundo e a eficácia da EPA em relação à cobertura universal de saúde e acesso à saúde. dada a evidência da sua eficácia em muitos países, as funções da EPA são ideais como parte de uma estratégia de recursos humanos de atenção primária de saúde na América Latina para melhorar a cobertura universal de saúde e o acesso à saúde. Brasil, Chile, Colômbia e México estão bem posicionados para construir esta força de trabalho. Barreiras à implementação destas funções incluem: a falta de clareza do seu papel, a legislação/regulamentação, educação, financiamento, e a resistência médica. Uma liderança forte de enfermagem é necessária para alinhar o papel da EPA com as prioridades políticas e trabalhar em colaboração com os profissionais de atenção primária e os decisores políticos para a implementação bem sucedida das suas funções. dada a diversidade de contextos dos diferentes países, é importante avaliar sistematicamente as necessidades de saúde do país e da população para introduzir a combinação mais adequada e complementar dos papéis da EPA e formatar sua aplicação. A introdução bem sucedida do papel da EPA na América Latina e no Caribe poderia fornecer um roteiro para funções semelhantes noutros países de baixa/média renda. examinar el rol de la enfermería con práctica avanzada (EPA) a nivel internacional para informar de su desarrollo en América Latina y el Caribe, en apoyo a la cobertura de salud universal y el acceso universal a la salud. se analizó la literatura relacionada con los roles de la EPA, su despliegue en el mundo y la eficacia de EPA en relación con la cobertura de salud universal y el acceso a la salud. dada la evidencia de su eficacia en muchos países, las funciones de la EPA son ideales como parte de una estrategia de recursos humanos de atención primaria de salud en América Latina para mejorar la cobertura de salud universal y el acceso a la salud. Brasil, Chile, Colombia y México están bien posicionados para construir esta fuerza de trabajo. Las barreras a la implementación de estas funciones incluyen: la falta de claridad de su rol, la legislación/regulación, educación, financiamiento, y la resistencia de los médicos. Se necesita un liderazgo fuerte de enfermería para alinear los roles de la EPA con las políticas prioritarias, y trabajar en colaboración con los profesionales de atención primaria y los responsables de las políticas para la implementación exitosa de sus funciones. teniendo en cuenta la diversidad de los contextos en diferentes naciones, es importante evaluar sistemáticamente las necesidades de salud del país y de la población para introducir la combinación más adecuada y complementaria de los papeles de la EPA y dar un formato a su aplicación. La introducción con éxito del papel de la EPA en América Latina y el Caribe podría proporcionar una hoja de ruta para funciones similares en otros países de bajos/medios ingresos.
Sociodemographic and health factors associated with mortality in community-dwelling elderly.
Borim, Flávia Silva Arbex; Francisco, Priscila Maria Stolses Bergamo; Neri, Anita Liberalesso
2017-05-04
The objective of this study is to identify factors associated with mortality, with emphasis on gender and age differences. This is a cross-sectional study, which uses data from the FIBRA-2008-2009 network in Campinas, State of São Paulo, Brazil, with information on non-institutionalized residents of the urban area and the Mortality Information System. The dependent variable has been death, in 2013. The associations have been tested by odds ratio (OR) and their 95% confidence intervals, and the analyses have been conducted using the program Stata 12.0. Average age has been 72.3 years, 69.3% have been women, and 8.9% have died. We have found greater OR for mortality in individuals aged ≥ 75 years, classified as pre-frail or frail, and in those who have reported heart disease. In this study, the analysis of specific subgroups has allowed us to better understand the relationship between the factors associated with death in the elderly. With the exception of age, strategies based on primary and secondary care, focused on priority groups, can have a positive impact on the reduction of mortality among the elderly. Identificar fatores associados à mortalidade, com ênfase nas diferenças de gênero e idade. Trata-se de estudo transversal, utilizando dados provenientes da rede FIBRA-2008-2009 em Campinas, SP, com informações de pessoas não institucionalizadas residentes na área urbana e pelo Sistema de Informações de Mortalidade. A variável dependente foi a ocorrência de óbito, verificada em 2013. As associações foram testadas pelas razões de chances (OR) e respectivos intervalos de confiança de 95%, e as análises conduzidas no programa Stata 12.0. A média de idade foi 72,3 anos, 69,3% eram mulheres e 8,9% foram a óbito. Encontrou-se maior OR para mortalidade nos indivíduos com idade ≥ 75 anos, nos classificados como pré-frágil ou frágil e naqueles que referiram doença do coração. Neste estudo, a análise para os subgrupos específicos permitiu melhor compreender a relação entre fatores que se associam ao óbito no idoso. Com exceção da idade, estratégias baseadas no cuidado específico de atenção primária e secundária, direcionadas a grupos prioritários, podem ter um impacto positivo na redução da mortalidade entre os idosos.
1985-01-01
lbs. at STA 117. Rlando Vibration MIL-STD-1SOC. Method. 514.2, 20-2w000 z at Wo a .04S2/Rz, I bour each axis. lhock NIL4- TD -8IOC, Method 516.2...day-. FULL FAR FIELD O-NE CUT INFAR FIELD 0 NBS BENCHMARK TIME 1000sm 0 TD 13ENCHMARK TIME __ 1 hou .j SPHERICAL OR PLANE, POLAR 1000 sec 20 60 100...for the coupling: bBd h ’(kd)IO d> 6 + (4) "-.(4) a2 nnedd an 32 1), i) fljfi f*f P(cose) si d do (5) 630 The spherical Hankel function of the first
NASA/USRA University advanced design program
NASA Technical Reports Server (NTRS)
Lembeck, Michael F.; Prussing, John
1989-01-01
The participation of the University of Illinois at Urbana-Champaign in the NASA/USRA University Advanced Design Program for the 1988 to 1989 academic year is reviewed. The University's design project was the Logistics Resupply and Emergency Crew Return System for Space Station Freedom. Sixty-one students divided into eight groups, participated in the spring 1989 semester. A presentation prepared by three students and a graduate teaching assistant for the program's summer conference summarized the project results. Teamed with the NASA Marshall Space Flight Center (MSFC), the University received support in the form of remote telecon lectures, reference material, and previously acquired applications software. In addition, a graduate teaching assistant was awarded a summer 1989 internship at MSFC.
Inertial-Electrostatic Confinement (IEC) Fusion for Space Propulsion
NASA Technical Reports Server (NTRS)
Nadler, Jon
1999-01-01
An Inertial-Electrostatic Confinement (IEC) device was assembled at the Marshall Space Flight Center (MSFC) Propulsion Research Center (PRC) to study the possibility of using EEC technology for deep space propulsion and power. Inertial-Electrostatic Confinement is capable of containing a nuclear fusion plasma in a series of virtual potential wells. These wells would substantially increase plasma confinement, possibly leading towards a high-gain, breakthrough fusion device. A one-foot in diameter IEC vessel was borrowed from the Fusion Studies Laboratory at the University of Illinois@Urbana-Champaign for the summer. This device was used in initial parameterization studies in order to design a larger, actively cooled device for permanent use at the PRC.
Inertial-Electrostatic Confinement (IEC) Fusion For Space Propulsion
NASA Technical Reports Server (NTRS)
Nadler, Jon
1999-01-01
An Inertial-Electrostatic Confinement (IEC) device was assembled at the Marshall Space Flight Center (MSFC) Propulsion Research Center (PRC) to study the possibility of using IEC technology for deep space propulsion and power. Inertial-Electrostatic Confinement is capable of containing a nuclear fusion plasma in a series of virtual potential wells. These wells would substantially increase plasma confinement, possibly leading towards a high-gain, breakthrough fusion device. A one-foot in diameter IEC vessel was borrowed from the Fusion Studies Laboratory at the University of Illinois @ Urbana-Champaign for the summer. This device was used in initial parameterization studies in order to design a larger, actively cooled device for permanent use at the PRC.
NASA Astrophysics Data System (ADS)
The Third International Conference on Urban Storm Drainage will be held in Goteborg, Sweden, June 4-8, 1984. Contact A. Sjoborg, Chalmers Univ. of Technology, Goteborg, Sweden, for more information. The Fourth Conference will be in late August 1987 in Lausanne, Switzerland, and the Fifth Conference is planned for Tokyo in 1990. The proceedings of the First International Conference, held in Southampton, England, in April 1978, are available from Wiley-Interscience under the title “Urban Storm Drainage.”The proceedings of the Second International Conference, held in Urbana, Illinois, in June 1981, are available from Water Resources Publications, Littleton, Colo., under the title, “Urban Stormwater Hydraulics and Hydrology” and “Urban Stormwater Quality, Management, and Planning.”
Photonuclear sum rules and the tetrahedral configuration of He4
NASA Astrophysics Data System (ADS)
Gazit, Doron; Barnea, Nir; Bacca, Sonia; Leidemann, Winfried; Orlandini, Giuseppina
2006-12-01
Three well-known photonuclear sum rules (SR), i.e., the Thomas-Reiche-Kuhn, the bremsstrahlungs and the polarizability SR are calculated for He4 with the realistic nucleon-nucleon potential Argonne V18 and the three-nucleon force Urbana IX. The relation between these sum rules and the corresponding energy weighted integrals of the cross section is discussed. Two additional equivalences for the bremsstrahlungs SR are given, which connect it to the proton-neutron and neutron-neutron distances. Using them, together with our result for the bremsstrahlungs SR, we find a deviation from the tetrahedral symmetry of the spatial configuration of He4. The possibility to access this deviation experimentally is discussed.
Historical anthropogenic and biofuel burning emissions of carbon monoxide, 1850-2000
NASA Astrophysics Data System (ADS)
Liu, L.; Zarzycki, C. M.; Winijkul, E.; Bond, T. C.
2011-12-01
Liang Liu, Colin Zarzycki, Ekbordin Winijkul, Tami C. Bond Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA Carbon monoxide (CO) plays an important role in atmospheric chemistry by acting as the primary sink of the most important atmospheric oxidizer, hydroxyl radicals (OH), and participating in the cycle of tropospheric ozone. CO can also provide constraints on model prediction of black carbon (BC) and vice versa due to their common sources of incomplete combustion. A well developed historical emission inventory of CO would serve the purpose of various global atmospheric models over the historical record. Only a few attempts have been made to represent the time dependence of CO emissions. In this study, we present the first technology based global historical trend of anthropogenic and biofuel emissions of CO from 1850 to 2000. The essential components of a bottom-up emission inventory are technology divisions, fuel consumptions for each technology, and emission factors for each combination of fuel and technology. Previous research done by Bond et al., [2007] has provided this study with technology breakdowns for different combinations of fuel and usage and the time trends of fuel-use for each specific technology in activities that contribute to BC emissions. This work reconstructs the fuel-use trend of the brick and cement industries which were not included in the historical BC emission inventory but play an important role in CO emission. Emission factors are developed for past and present CO emitters. Fuel consumption and emission factors are then combined to estimate global CO emissions at the country level. Uncertainty analysis in activity data, technology splits, and emission factors are performed. The developed historical CO emission trend is compared with the historical BC emission trend to provide more insight into the relationship of the two pollutants.
Advanced engineering design program at the University of Illinois for the 1987-1988 academic year
NASA Technical Reports Server (NTRS)
Sivier, Kenneth R.; Lembeck, Michael F.
1988-01-01
The participation of the University of Illinois at Urbana-Champaign in the NASA/USRA Universities Advanced Engineering Design Program (Space) is reviewed for the 1987 to 88 academic year. The University's design project was the Manned Marsplane and Delivery System. In the spring of 1988 semester, 107 students were enrolled in the Aeronautical and Astronautical Engineering Departments' undergraduate Aerospace Vehicle Design course. These students were divided into an aircraft section (responsible for the Marsplane design), and a spacecraft section (responsible for the Delivery System Design). The design results are presented in Final Design Reports, copies of which are attached. In addition, five students presented a summary of the design results at the Program's Summer Conference.
Code of Federal Regulations, 2012 CFR
2012-07-01
... NA NA NA NA NA NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui NA NA NA NA NA NA 0.23... NA NA NA NA NA In Situ Thermal Cleaning: 1-Ui NA NA NA NA NA NA 0.28 NA NA NA NA BCF4 NA NA NA NA NA...
Calibration of the Urbana lidar system
NASA Technical Reports Server (NTRS)
Cerny, T.; Sechrist, C. F., Jr.
1980-01-01
A method for calibrating data obtained by the Urban sodium lidar system is presented. First, an expression relating the number of photocounts originating from a specific altitude range to the soodium concentration is developed. This relation is then simplified by normalizing the sodium photocounts with photocounts originating from the Rayleigh region of the atmosphere. To evaluate the calibration expression, the laser linewidth must be known. Therefore, a method for measuring the laser linewidth using a Fabry-Perot interferometer is given. The laser linewidth was found to be 6 + or - 2.5 pm. Problems due to photomultiplier tube overloading are discussed. Finally, calibrated data is presented. The sodium column abundance exhibits something close to a sinusoidal variation throughout the year with the winter months showing an enhancement of a factor of 5 to 7 over the summer months.
NASA Astrophysics Data System (ADS)
Representatives of 69 countries, five United Nations organizations, and eight international non-governmental organizations (NGO) met March 19-24, 1990, in Paris, France, at the headquarters of the United Nations Educational, Scientific and Cultural Organization to evaluate and approve projects for the fourth phase of the International Hydrological Program (IHP-IV), which will be active during 1990-1995. The International Association of Hydrological Sciences was represented by AGU members and IAHS officers Vit Klemes, President, University of Victoria, Victoria, Canada; Henny Colenbrander, Secretary General, TNO, The Hague, The Netherlands; and Ivan Johnson, Honorary President, A. Ivan Johnson, Inc., Arvada, Colo. The International Water Resources Association was represented by AGU member and IWRA Secretary General Glenn Stout, IWRA, Urbana, 111. The U.S. representatives (observer status) were David Rickert, U.S. Geological Survey, Reston, Va., and Glenn Stout.
Code of Federal Regulations, 2013 CFR
2013-07-01
... C5F8 C4F8O Plasma Etching 1-Ui 0.80 0.80 0.48 0.14 NA 0.29 0.32 0.37 0.09 NA NA BCF4 NA NA 0.0018 0... NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui NA NA NA NA NA NA 0.23 NA NA NA NA BCF4... NA NA NA NA NA Remote Plasma Cleaning: 1-Ui NA NA NA NA 0.063 NA 0.018 NA NA NA NA BCF4 NA NA NA NA...
Use of medicines and other products for therapeutic purposes among children in Brazil.
Pizzol, Tatiane da Silva Dal; Tavares, Noemia Urruth Leão; Bertoldi, Andréa Dâmaso; Farias, Mareni Rocha; Arrais, Paulo Sergio Dourado; Ramos, Luiz Roberto; Oliveira, Maria Auxiliadora; Luiza, Vera Lucia; Mengue, Sotero Serrate
2016-12-01
To assess the prevalence of the use of medicines and other products for therapeutic purposes in the Brazilian pediatric population and test whether demographic, socioeconomic and health factors are associated with use. A cross-sectional population-based study (National Survey on Access, Use and Promotion of Rational Use of Medicines - PNAUM), including 7,528 children aged 12 or younger, living in urban areas in Brazil. Medicine use to treat chronic or acute diseases was reported by the primary caregiver present at the household interview. Associations between independent variables and medicine use were investigated by Poisson regression. The overall prevalence of medicine use was 30.7% (95%CI 28.3-33.1). The prevalence of medicine use for chronic diseases was 5.6% (95%CI 4.7-6.7) and for acute conditions, 27.1% (95%CI 24.8-29.4). The factors significantly associated with overall use were five years old or under, living in the Northeast region, having health insurance and using health services in the last 12 months (emergency visits and hospitalizations). The following were associated with drug use for chronic diseases: age ≥ 2 years, Southeast and South regions, and use of health services. For drug use in treating acute conditions, the following associated factors were identified: ≤ 5 years, North, Northeast or Midwest regions, health insurance, and one or more emergency visits. The most commonly used drugs among children under two years of age were paracetamol, ascorbic acid, and dipyrone; for children aged two years or over they were dipyrone, paracetamol, and amoxicillin. The use of medicine by children is considerable, especially in treating acute medical conditions. Children using drugs for chronic diseases have a different demographic profile from those using drugs for acute conditions in relation to gender, age, and geographic region. Estimar a prevalência de uso de medicamentos e outros produtos com finalidade terapêutica na população pediátrica brasileira e testar se fatores demográficos, socioeconômicos e médicos estão associados ao uso. Estudo transversal de base populacional (Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - PNAUM), incluindo 7.528 crianças com 12 anos ou menos de idade, residentes na zona urbana do território brasileiro. O uso de medicamentos para tratar doenças crônicas ou agudas foi referido pelo principal cuidador da criança presente na entrevista domiciliar. Associações entre as variáveis independentes e o uso de medicamentos foram investigadas por meio de regressão de Poisson. A prevalência de uso global de medicamentos foi de 30,7% (IC95% 28,3-33,1). A prevalência de uso de medicamentos para doenças crônicas foi de 5,6% (IC95% 4,7-6,7) e para condições agudas, 27,1% (IC95% 24,8-29,4). Os fatores significativamente associados com o uso global foram ter no máximo cinco anos de idade, residir na região Nordeste, ter plano de saúde e utilizar serviços de saúde nos últimos 12 meses (consultas de emergência e internações). Associaram-se ao uso de medicamentos para doenças crônicas: idade ≥ 2 anos, regiões Sudeste e Sul e utilização de serviços de saúde. Para o uso de medicamentos em condições agudas, foram identificados os seguintes fatores associados: ≤ 5 anos, Norte, Nordeste ou Centro-Oeste, plano de saúde e uma ou mais consultas de emergência. Os medicamentos com maior prevalência de uso pelas crianças menores de dois anos foram paracetamol, ácido ascórbico e dipirona; nas crianças com 2 ou mais anos, foram dipirona, paracetamol e amoxicilina. O uso de medicamentos na população infantil é substancial, principalmente no tratamento de condições médicas agudas. As crianças usuárias de medicamentos para doenças crônicas apresentam perfil demográfico diferente das usuárias de medicamentos para condições agudas, em relação ao sexo, à idade e à região geográfica.
Code of Federal Regulations, 2012 CFR
2012-07-01
... C4F6 C5F8 C4F8O Plasma Etching 1-Ui 0.69 0.56 0.38 0.093 NA 0.25 0.038 0.20 0.14 NA NA BCF4 NA 0.23 0... NA NA NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui 0.92 0.55 NA NA 0.40 0.10 0.18 NA... BC3F8 NA NA NA NA NA NA NA NA NA NA NA Remote plasma cleaning: 1-Ui NA NA NA NA NA NA 0.018 NA NA NA NA...
Code of Federal Regulations, 2013 CFR
2013-07-01
... C4F6 C5F8 C4F8O Plasma Etching 1-Ui 0.69 0.56 0.38 0.093 NA 0.25 0.038 0.20 0.14 NA NA BCF4 NA 0.23 0... NA NA NA NA NA NA NA Chamber Cleaning In situ plasma cleaning: 1-Ui 0.92 0.55 NA NA 0.40 0.10 0.18 NA... BC3F8 NA NA NA NA NA NA NA NA NA NA NA Remote plasma cleaning: 1-Ui NA NA NA NA NA NA 0.018 NA NA NA NA...
Daytime lidar measurements of tidal winds in the mesospheric sodium layer at Urbana, Illinois
NASA Technical Reports Server (NTRS)
Kwon, K. H.; Senft, D. C.; Gardner, C. S.; Voelz, D. G.; Sechrist, C. F., Jr.; Roesler, F. L.
1986-01-01
For more than 15 years lidar systems have been used to study the chemistry and dynamics of the mesospheric sodium layer. Because the layer is an excellent tracer of atmospheric wave motions, sodium lidar has proven to be particularly useful for studying the influence of gravity waves and tides on mesospheric dynamics. These waves, which originate in the troposphere and stratosphere, propagate through the mesosphere and dissipate their energy near the mesopause making important contributions to the momentum and turbulence budget in this region of the atmosphere. Recently, the sodium lidar was modified for daytime operation so that wave phenomena and chemical effects could be monitored throughout the complete diurnal cycle. The results of continuous 24 hour lidar observations of the sodium layer structure are presented alond with measurement of the semidiurnal tidal winds.
2006-04-01
b. Principles of Decontamination Operations. Decontaminate immediately for an agent on the skin . Perform higher levels of decontamination as a...the mask and hood with paper towels or rags. NOTE: Cool, soapy water is not as effective for removing contamination, but it can be used if you scrub ...N/A N/A 5 N/A Sponge, cellulose II Each As required N/A N/A N/A N/A 2 N/A 4 6 Brush, scrub II Each As required N/A N/A N/A N/A 2 N/A 2 N/A Towels
Overby, L. R.; Barlow, G. H.; Doi, R. H.; Jacob, Monique; Spiegelman, S.
1966-01-01
Overby, L. R. (University of Illinois, Urbana), G. H. Barlow, R. H. Doi, Monique Jacob, and S. Spiegelman. Comparison of two serologically distinct ribonucleic acid bacteriophages. I. Properties of the viral particle. J. Bacteriol. 91:442–448. 1966.—Two ribonucleic acid (RNA) coliphages, MS-2 and Qβ, have been characterized physically and serologically. MS-2 has an S20, w value of 79, a molecular weight of 3.6 × 106, a density of 1.422, and pH 3.9 as its isoelectric point. Qβ has an S20, w of 84, a molecular weight of 4.2 × 106, a density of 1.439, and an isoelectric point at pH 5.3. One host (Escherichia coli A-19) permits a distinction between the two on the basis of a marked difference in plaque size. They are distinct immunochemically, no serological cross-reaction being detectable. Images PMID:5903109
JCESR Scientific Sprints – Better Polymers for Better Batteries
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brushett, Fikile; Moore, Jeff; Zhang, Lu
2016-02-19
Argonne National Laboratory leads the Joint Center for Energy Storage Research (JCESR), a major collaborative research partnership with the goal of developing next-generation energy storage technologies. JCESR supplements its traditional project management approach with scientific “Sprints.” The Sprint described in this video involved a multidisciplinary team from Argonne, the University of Illinois at Urbana-Champaign, Massachusetts Institute of Technology, and the University of Michigan. As they studied how polymers in solution can react electrochemically to store energy, the team solved a crucial battery problem: “crossover,” which is caused by molecules mixing together when they should not, resulting in reduced performance. Manymore » possible materials were tested, and a set of candidate polymers were chosen that are stable, cheap to make, and suitable for conditions required in batteries. The collaboration allowed timely development that would have taken much longer had the groups been working independently.« less
The Effects of the Critical Ice Accretion on Airfoil and Wing Performance
NASA Technical Reports Server (NTRS)
Selig, Michael S.; Bragg, Michael B.; Saeed, Farooq
1998-01-01
In support of the NASA Lewis Modern Airfoils Ice Accretion Test Program, the University of Illinois at Urbana-Champaign provided expertise in airfoil design and aerodynamic analysis to determine the aerodynamic effect of ice accretion on modern airfoil sections. The effort has concentrated on establishing a design/testing methodology for "hybrid airfoils" or "sub-scale airfoils," that is, airfoils having a full-scale leading edge together with a specially designed and foreshortened aft section. The basic approach of using a full-scale leading edge with a foreshortened aft section was considered to a limited extent over 40 years ago. However, it was believed that the range of application of the method had not been fully exploited. Thus a systematic study was being undertaken to investigate and explore the range of application of the method so as to determine its overall potential.
Lidar observations of wave-like structure in the atmospheric sodium layer
NASA Technical Reports Server (NTRS)
Rowlett, J. R.; Gardner, C. S.; Richter, E. S.; Sechrist, C. F., Jr.
1978-01-01
The University of Illinois (Urbana) lidar system has been developed to study the atmospheric sodium layer near 90 km altitude through the mechanism of resonance scattering. The photocount data are processed using digital smoothing filters to obtain continuous estimates of the sodium density versus altitude. The filter cutoff frequency is related to the height resolution and accuracy of the estimated profile. Lidar photocount data processed using this filtering technique show wave-like structures in the sodium layer which move downward with time. The waves have typical wavelengths of 3-15 km and phase velocities of less than 1 m/sec. The movement of these structures seems to be independent of the motion of the bottomside of the layer, which also has been observed to move up or down by as much as 2 km over a period of a few hours.
NASA Astrophysics Data System (ADS)
Parsons, Matthew; Tang, William; Feibush, Eliot
2016-10-01
Plasma disruptions pose a major threat to the operation of tokamaks which confine a large amount of stored energy. In order to effectively mitigate this damage it is necessary to predict an oncoming disruption with sufficient warning time to take mitigative action. Machine learning approaches to this problem have shown promise but require further developments to address (1) the need for machine-portable predictors and (2) the availability of multi-dimensional signal inputs. Here we demonstrate progress in these two areas by applying the Disruption Predictor Feature Developer to data from JET and NSTX, and discuss topics of focus for ongoing work in support of ITER. The author is also supported under the Fulbright U.S. Student Program as a graduate student in the department of Nuclear, Plasma and Radiological Engineering at the University of Illinois at Urbana-Champaign.
Progress on the Development of the hPIC Particle-in-Cell Code
NASA Astrophysics Data System (ADS)
Dart, Cameron; Hayes, Alyssa; Khaziev, Rinat; Marcinko, Stephen; Curreli, Davide; Laboratory of Computational Plasma Physics Team
2017-10-01
Advancements were made in the development of the kinetic-kinetic electrostatic Particle-in-Cell code, hPIC, designed for large-scale simulation of the Plasma-Material Interface. hPIC achieved a weak scaling efficiency of 87% using the Algebraic Multigrid Solver BoomerAMG from the PETSc library on more than 64,000 cores of the Blue Waters supercomputer at the University of Illinois at Urbana-Champaign. The code successfully simulates two-stream instability and a volume of plasma over several square centimeters of surface extending out to the presheath in kinetic-kinetic mode. Results from a parametric study of the plasma sheath in strongly magnetized conditions will be presented, as well as a detailed analysis of the plasma sheath structure at grazing magnetic angles. The distribution function and its moments will be reported for plasma species in the simulation domain and at the material surface for plasma sheath simulations. Membership Pending.
History society launches journal
NASA Astrophysics Data System (ADS)
Richman, Barbara T.
A fledgling international organization plans to launch, in the next few months, a journal devoted to the study of the history of the earth sciences. The journal, to be published by the History of Earth Sciences Society (HESS), will be edited by Gerald M. Friedman ot the Rensselaer Polytechnic Institute.HESS will promote interest and scholarship in the history of the earth sciences by publishing the semiannual journal, by organizing meetings about the history of earth sciences, and by supporting the efforts of other associations displaying similar interests, according to the society's draft constitution. An organizational meeting to ratify the constitution and to elect officers will be held in conjunction with the annual meeting of the Geological Society of America in October. The interim officers and the proposed slate for 1983 include David B. Kitts (University of Oklahoma, Norman), president; Albert V. Carrozi (University of Illinois, Urbana), president-elect; and Ellis L. Yochelson (U.S. Geological Survey, National Museum of Natural History), secretary.
Data harmonization and model performance
NASA Astrophysics Data System (ADS)
The Joint Committee on Urban Storm Drainage of the International Association for Hydraulic Research (IAHR) and International Association on Water Pollution Research and Control (IAWPRC) was formed in 1982. The current committee members are (no more than two from a country): B. C. Yen, Chairman (USA); P. Harremoes, Vice Chairman (Denmark); R. K. Price, Secretary (UK); P. J. Colyer (UK), M. Desbordes (France), W. C. Huber (USA), K. Krauth (FRG), A. Sjoberg (Sweden), and T. Sueishi (Japan).The IAHR/IAWPRC Joint Committee is forming a Task Group on Data Harmonization and Model Performance. One objective is to promote international urban drainage data harmonization for easy data and information exchange. Another objective is to publicize available models and data internationally. Comments and suggestions concerning the formation and charge of the Task Group are welcome and should be sent to: B. C. Yen, Dept. of Civil Engineering, Univ. of Illinois, 208 N. Romine St., Urbana, IL 61801.
JCESR Scientific Sprints â Better Polymers for Better Batteries
Brushett, Fikile; Moore, Jeff; Zhang, Lu; Rodriguez-Lopez, Joaquin; Sevov, Christo; Gavvalapalli, Nagarjuna; Montoto, Elena
2018-06-25
Argonne National Laboratory leads the Joint Center for Energy Storage Research (JCESR), a major collaborative research partnership with the goal of developing next-generation energy storage technologies. JCESR supplements its traditional project management approach with scientific âSprints.â The Sprint described in this video involved a multidisciplinary team from Argonne, the University of Illinois at Urbana-Champaign, Massachusetts Institute of Technology, and the University of Michigan. As they studied how polymers in solution can react electrochemically to store energy, the team solved a crucial battery problem: âcrossover,â which is caused by molecules mixing together when they should not, resulting in reduced performance. Many possible materials were tested, and a set of candidate polymers were chosen that are stable, cheap to make, and suitable for conditions required in batteries. The collaboration allowed timely development that would have taken much longer had the groups been working independently.
100 years of Pb deposition and transport in soils in Champaign, Illinois, U.S.A
Zhang, Y.
2003-01-01
In Illinois, atmospheric deposition is one major source of heavy metal inputs to agricultural land. The atmospheric Pb deposition and transport record in agricultural soils in Champaign, Illinois, was established by studying surface and subsurface soil samples collected during the past 100 years from the Morrow Plots on the campus of the University of Illinois at Urbana-Champaign. The Pb content in the soil samples was measured and the Ph deposition fluxes were calculated. The Pb content in surface soils increased sharply in the first half of the 20th century, and stayed invariant since. The maximum Pb flux from the atmosphere was estimated to be 27 (??14) ??g cm-2 yr-1 around 1940. The major pollution source for this increase probably was residential coal burning. It was estimated that in 50 yr, more than 50% of the Pb input had been lost from the surface soils.
Using multimedia learning modules in a hybrid-online course in electricity and magnetism
NASA Astrophysics Data System (ADS)
Sadaghiani, Homeyra R.
2011-06-01
We have been piloting web-based multimedia learning modules (MLMs), developed by the Physics Education Research Group at the University of Illinois at Urbana Champaign (UIUC), as a “prelecture assignment” in several introductory physics courses at California State Polytechnic University at Pomona. In this study, we report the results from a controlled study utilizing modules on electricity and magnetism as a part of a blended hybrid-online course. We asked students in the experimental section to view the MLMs prior to attending the face-to-face class, and to make sure this would not result in additional instructional time, we reduced the weekly class time by one-third. We found that despite reduced class time, student-learning outcomes were not hindered; in fact, the implementation of the UIUC MLMs resulted in a positive effect on student performance on conceptual tests and classroom discussion questions.
Research productivity in select psychology journals, 1986-2008.
Mahoney, Kevin T; Buboltz, Walter C; Calvert, Barbara; Hoffmann, Rebecca
2010-01-01
Examination of research productivity has a long history in psychology. Journals across psychology have periodically published research-productivity studies. An analysis of institutional research productivity was conducted for 17 journals published by the American Psychological Association for the years 1986-2008. This analysis implemented two methodologies: one a replication and extension of G. S. Howard, D. A. Cole, and S. E. Maxwell's (1987) method, the other a new method designed to give credit to psychology departments rather than only overall institutions. A system of proportional credit assured all articles with multiple institutions received credit. Results show that for the 23-year period, the University of Illinois at Urbana-Champaign was ranked 1st, followed by the University of California, Los Angeles, and the University of Michigan, Ann Arbor. Overall, results showed both consistency and change across all journals examined. The authors explore the implications of these findings in the context of the current academic environment.
2002-02-19
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2002-02-24
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Sustainability Product Properties in Building Information Models
2012-09-01
Covrlhovses, Oota c enters, Hospitals IAcvle care and Children’s), Hotels/ Mote ~, Hovses of Worship, K- 12 Schools, Med1cal Offic&s, Offices, Restdence Holts...RenewableContent n/a n/a 70 RenewableMaterial n/a n/a Cotton BiobasedContent n/a n/a 70 BiobasedMaterial n/a n/a Cotton RawMaterialLocation n/a n/a
Study of Cetane Properties of ATJ Blends Based on World Survey of Jet Fuels
2016-01-28
49.84 N/A N/A N/A 46.92 N/A N/A N/A 12 (100% Syn.) 1 57.79 N/A N/A N/A 53.48 N/A N/A N/A a - Conventional petroleum based jet fuel; b - Oil Shale ...Australia (% Nitrogen content unknown) c - Oil Shale , Australia (Low Nitrogen); d - Oil Shale , Australia (High Nitrogen) U/A – Unavailable in PQIS...fuel b - Oil Shale , Australia (% Nitrogen content unknown) c - Oil Shale , Australia (Low Nitrogen) d - Oil Shale , Australia (High Nitrogen) U/A
Formation of Si grains from a NaSi melt prepared by reaction of SiO2 and Na
NASA Astrophysics Data System (ADS)
Yamane, Hisanori; Morito, Haruhiko; Uchikoshi, Masahito
2013-08-01
A mixture of Na2SiO3 and NaSi was found to be formed by reaction of SiO2 and Na at 650 °C as follows: 5Na+3SiO2→2Na2SiO3+NaSi. Single crystals of NaSi were grown by cooling the mixture of Na2SiO3 and NaSi with an excess amount of Na from 850 °C, and polycrystalline Si was obtained by vaporization of Na from the crystals. Coarse grains of Si were also crystallized by Na evaporation after the formation of Na2SiO3 and Si-dissolved liquid Na at 830 °C. The Si grains were collected by washing the product with water. The yield of the Si grains was 85% of the ideal amount expected from the reaction.
Condition of Si crystal formation by vaporizing Na from NaSi
NASA Astrophysics Data System (ADS)
Morito, Haruhiko; Karahashi, Taiki; Yamane, Hisanori
2012-09-01
NaSi was heated at various Na vapor pressures (pNa 0.1-1.2 atm) and temperatures (973-1173 K) to investigate the condition of Si crystal formation from NaSi by Na evaporation. Silicon single crystals 1-3 mm in diameter were grown by evaporation of Na from Na-Si melt at 1173 K and pNa=0.74 atm.
NMR studies on Na+ transport in Synechococcus PCC 6311
NASA Technical Reports Server (NTRS)
Nitschmann, W. H.; Packer, L.
1992-01-01
The freshwater cyanobacterium Synechococcus PCC 6311 is able to adapt to grow after sudden exposure to salt (NaCl) stress. We have investigated the mechanism of Na+ transport in these cells during adaptation to high salinity. Na+ influx under dark aerobic conditions occurred independently of delta pH or delta psi across the cytoplasmic membrane, ATPase activity, and respiratory electron transport. These findings are consistent with the existence of Na+/monovalent anion cotransport or simultaneous Na+/H+ +anion/OH- exchange. Na+ influx was dependent on Cl-, Br-, NO3-, or NO2-. No Na+ uptake occurred after addition of NaI, NaHCO3, or Na2SO4. Na+ extrusion was absolutely dependent on delta pH and on an ATPase activity and/or on respiratory electron transport. This indicates that Na+ extrusion via Na+/H+ exchange is driven by primary H+ pumps in the cytoplasmic membrane. Cells grown for 4 days in 0.5 m NaCl medium, "salt-grown cells," differ from control cells by a lower maximum velocity of Na+ influx and by lower steady-state ratios of [Na+]in/[Na+]out. These results indicate that cells grown in high-salt medium increase their capacity to extrude Na+. During salt adaptation Na+ extrusion driven by respiratory electron transport increased from about 15 to 50%.
PREJUICIO Y DISTANCIA SOCIAL HACIA PERSONAS HOMOSEXUALES POR PARTE DE JÓVENES UNIVERSITARIOS
Fernández Rodríguez, María del C.; Squiabro, José Calderón
2014-01-01
Se realizó un estudio descriptivo transversal con el propósito de explorar actitudes de rechazo y distancia social hacia las personas gays y lesbianas (GL) en 565 universitarios. Se utilizó una escala para medir Prejuicio y otra escala para medir Distancia Social. Los participantes reflejaron niveles moderados de prejuicio y distancia social (DS) hacia las personas gays y lesbianas. Los varones (M=104.5, DT= 27.47) mostraron significativamente más prejuicio que las mujeres (M=98.8, DT= 23.41). Los hombres (M=22.7, DT= 7.00) mostraron significativamente mayor DS que las mujeres (M=21.1, DT= 5.41). Las personas que asisten con regularidad a la iglesia mostraron más prejuicio y DS que los que no asisten. Se analiza importancia de incluir el tema de la diversidad sexual a través del currículo para desmontar prejuicios hacia la comunidad homosexual. PMID:25606066
Lu, Fang-Min
2017-01-01
Decades ago, it was proposed that Na transport in cardiac myocytes is modulated by large changes in cytoplasmic Na concentration within restricted subsarcolemmal spaces. Here, we probe this hypothesis for Na/K pumps by generating constitutive transsarcolemmal Na flux with the Na channel opener veratridine in whole-cell patch-clamp recordings. Using 25 mM Na in the patch pipette, pump currents decay strongly during continuous activation by extracellular K (τ, ∼2 s). In contradiction to depletion hypotheses, the decay becomes stronger when pump currents are decreased by hyperpolarization. Na channel currents are nearly unchanged by pump activity in these conditions, and conversely, continuous Na currents up to 0.5 nA in magnitude have negligible effects on pump currents. These outcomes are even more pronounced using 50 mM Li as a cytoplasmic Na congener. Thus, the Na/K pump current decay reflects mostly an inactivation mechanism that immobilizes Na/K pump charge movements, not cytoplasmic Na depletion. When channel currents are increased beyond 1 nA, models with unrestricted subsarcolemmal diffusion accurately predict current decay (τ ∼15 s) and reversal potential shifts observed for Na, Li, and K currents through Na channels opened by veratridine, as well as for Na, K, Cs, Li, and Cl currents recorded in nystatin-permeabilized myocytes. Ion concentrations in the pipette tip (i.e., access conductance) track without appreciable delay the current changes caused by sarcolemmal ion flux. Importantly, cytoplasmic mixing volumes, calculated from current decay kinetics, increase and decrease as expected with osmolarity changes (τ >30 s). Na/K pump current run-down over 20 min reflects a failure of pumps to recover from inactivation. Simulations reveal that pump inactivation coupled with Na-activated recovery enhances the rapidity and effectivity of Na homeostasis in cardiac myocytes. In conclusion, an autoregulatory mechanism enhances cardiac Na/K pump activity when cytoplasmic Na rises and suppresses pump activity when cytoplasmic Na declines. PMID:28606910
Concentration dependence of Li+/Na+ diffusion in manganese hexacyanoferrates
NASA Astrophysics Data System (ADS)
Takachi, Masamitsu; Fukuzumi, Yuya; Moritomo, Yutaka
2016-06-01
Manganese hexacyanoferrates (Mn-HCFs) with a jungle-gym-type structure are promising cathode materials for Li+/Na+ secondary batteries (LIBs/SIBs). Here, we investigated the diffusion constants D Li/D Na of Li+/Na+ against the Li+/Na+ concentration x Na/x Li and temperature (T) of A 1.32Mn[Fe(CN)6]0.833.6H2O (A = Li and Na). We evaluated the activation energy E\\text{a}\\text{Li}/E\\text{a}\\text{Na} of D Li/D Na against x Na/x Li. We found that E\\text{a}\\text{Na} steeply increases with x Na from 0.41 eV at x Na = 0.69 to 0.7 eV at 1.1. The increase in E\\text{a}\\text{Na} is ascribed to the occupancy effect of the Na+ site. The increase in E\\text{a}\\text{Li} is suppressed, probably because the number of Li+ sites is three times that of Na+ sites.
Metal Residue Deposition from Military Pyrotechnic Devices and Field Sampling Guidance
2012-05-01
given NA 0.002 NA NA Chromium Oxide 1308-38-9 NA NA NA 0.015 Cobalt Naphthenate 61789-51-3 NA NA NA 0.017 Copper Oxide Black 1317-38-0 NA 1.32 NA...the whistling booby trap simulators included 73% potassium perchlorate, 24% gallic acid , and 3 % red gum (McIntyre 1980). Whereas the booby-trap...M21 Flash Artillery Simulator 50 3785.8 2/5/10 All – indicates the entire volume of stained snow was removed . MI – multi-increment. Rep
Radio Synthesis Imaging - A High Performance Computing and Communications Project
NASA Astrophysics Data System (ADS)
Crutcher, Richard M.
The National Science Foundation has funded a five-year High Performance Computing and Communications project at the National Center for Supercomputing Applications (NCSA) for the direct implementation of several of the computing recommendations of the Astronomy and Astrophysics Survey Committee (the "Bahcall report"). This paper is a summary of the project goals and a progress report. The project will implement a prototype of the next generation of astronomical telescope systems - remotely located telescopes connected by high-speed networks to very high performance, scalable architecture computers and on-line data archives, which are accessed by astronomers over Gbit/sec networks. Specifically, a data link has been installed between the BIMA millimeter-wave synthesis array at Hat Creek, California and NCSA at Urbana, Illinois for real-time transmission of data to NCSA. Data are automatically archived, and may be browsed and retrieved by astronomers using the NCSA Mosaic software. In addition, an on-line digital library of processed images will be established. BIMA data will be processed on a very high performance distributed computing system, with I/O, user interface, and most of the software system running on the NCSA Convex C3880 supercomputer or Silicon Graphics Onyx workstations connected by HiPPI to the high performance, massively parallel Thinking Machines Corporation CM-5. The very computationally intensive algorithms for calibration and imaging of radio synthesis array observations will be optimized for the CM-5 and new algorithms which utilize the massively parallel architecture will be developed. Code running simultaneously on the distributed computers will communicate using the Data Transport Mechanism developed by NCSA. The project will also use the BLANCA Gbit/s testbed network between Urbana and Madison, Wisconsin to connect an Onyx workstation in the University of Wisconsin Astronomy Department to the NCSA CM-5, for development of long-distance distributed computing. Finally, the project is developing 2D and 3D visualization software as part of the international AIPS++ project. This research and development project is being carried out by a team of experts in radio astronomy, algorithm development for massively parallel architectures, high-speed networking, database management, and Thinking Machines Corporation personnel. The development of this complete software, distributed computing, and data archive and library solution to the radio astronomy computing problem will advance our expertise in high performance computing and communications technology and the application of these techniques to astronomical data processing.
Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions.
Thiangtum, Wandee; Schonewille, J Thomas; Verstegen, Martin Wa; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H
2017-06-01
Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the subsequent rate of repletion. The rate of Na depletion and subsequent rate of Na repletion with two levels of dietary Na to lactating dairy cows housed under tropical conditions were investigated using the salivary Na/K. The 12 lactating cows (salivary Na/K ratio 14.6) rapidly developed clinical signs of Na deficiency, including pica, polyuria and polydipsia, reduced body weight and reduced milk yield when fed a low-Na ration (0.33 g kg -1 dry matter (DM)) for 3 weeks. Deficiency symptoms were associated with a rapid decrease in salivary Na/K ratio to <4.3 from 7 to 21 days. Subsequent repletion of the cows with NaCl to a ration concentration of 1.1 or 1.6 g Na kg -1 DM for 5 weeks did not restore salivary Na/K ratio to values of >6. A daily Na intake of heat-stressed lactating cows to a ration intake of 1.6 g Na kg -1 DM was insufficient to restore Na deficiency. One week was sufficient to deplete heat-stressed lactating cows of Na, allowing for rapid dose-response studies utilizing the salivary Na/K ratio as a parameter for Na status of cows under tropical conditions. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.
[Effects of different salt and alkali stresses on ion distribution in Red globe/Beta grapevines].
Du, Yuan-peng; Jin, Xue-juan; Guo, Shu-hua; Fu, Qing-qing; Zhai, Heng
2015-06-01
The potted Red globe/Beta grapevines were selected to irrigated with NaCl, Na2SO4, NaHCO3, NH4Cl, (NH4)2SO4. Hence, the ions which induced leaf etiolation were screened and the impacts of different salt and alkali on ion distribution in different organs of grapevines were investigated. It was found that NaHCO3 exerted the greatest effects on grapevines, leaf etiolation at 14 days after treatment. By contrast, NaCl and NH4Cl treatments induced leaf etiolation at 28 days after treatment. The Na+ content in all the detected organs were significantly increased under NaHCO3 and NaCl treatment, and Na+ content in root under NaHCO3 treatment was 6.4 times as that in control root. NaHCO3 and NaCl treatments significantly decreased K+ content in the organs with the exception of leaf. NaHCO3 treatment significantly decreased K/Na in different organs, which declined to 0.1 in root. By contrast, NaCl treatment significantly decreased K/Na in the detected organs with exception of stem. Besides, the transport of Ca2+, Mg2+, Fe2+ to aboveground organs was significantly decreased by NaHCO3 and NaCl treatments. K/Na ratio in the detected organs were decreased under NH4Cl, (NH4) 2SO4 and Na2SO4 treatments, especially under NH4 Cl treatment. Taken together, NaHCO3 was the primary factor resulting in leaf etiolation, followed by NaCl and NH4Cl, while (NH4) 2SO4 and Na2SO4 produced impacts.
Thermal decomposition of sodium amide, NaNH2, and sodium amide hydroxide composites, NaNH2-NaOH.
Jepsen, Lars H; Wang, Peikun; Wu, Guotao; Xiong, Zhitao; Besenbacher, Flemming; Chen, Ping; Jensen, Torben R
2016-09-14
Sodium amide, NaNH 2 , has recently been shown to be a useful catalyst to decompose NH 3 into H 2 and N 2 , however, sodium hydroxide is omnipresent and commercially available NaNH 2 usually contains impurities of NaOH (<2%). The thermal decomposition of NaNH 2 and NaNH 2 -NaOH composites is systematically investigated and discussed. NaNH 2 is partially dissolved in NaOH at T > 100 °C, forming a non-stoichiometric solid solution of Na(OH) 1-x (NH 2 ) x (0 < x < ∼0.30), which crystallizes in an orthorhombic unit cell with the space group P2 1 2 1 2 1 determined by synchrotron powder X-ray diffraction. The composite xNaNH 2 -(1 - x)NaOH (∼0.70 < x < 0.72) shows a lowered melting point, ∼160 °C, compared to 200 and 318 °C for neat NaNH 2 and NaOH, respectively. We report that 0.36 mol of NH 3 per mol of NaNH 2 is released below 400 °C during heating in an argon atmosphere, initiated at its melting point, T = 200 °C, possibly due to the formation of the mixed sodium amide imide solid solution. Furthermore, NaOH reacts with NaNH 2 at elevated temperatures and provides the release of additional NH 3 .
Babsky, Andriy M; Topper, Stephen; Zhang, Hong; Gao, Yong; James, Judy R; Hekmatyar, Shahryar K; Bansal, Navin
2008-03-01
The mechanism of water and sodium apparent diffusion coefficient (ADC) changes in rat skeletal muscle during global ischemia was examined by in vivo 1H and 23Na magnetic resonance spectroscopy (MRS). The ADCs of Na+ and water are expected to have similar characteristics because sodium is present as an aqua-cation in tissue. The shift reagent, TmDOTP5(-), was used to separate intra- and extracellular sodium (Na+i and Na+e, respectively) signals. Water, total tissue sodium (Na+t), Na+i, and Na+e ADCs were measured before and 1, 2, 3, and 4 hr after ischemia. Contrary to the general perception, Na+i and Na+e ADCs were identical before ischemia. Thus, ischemia-induced changes in Na+e ADC cannot be explained by a simple change in the size of relative intracellular or extracellular space. Na+t and Na+e ADCs decreased after 2-4 hr of ischemia, while water and Na+i ADC remained unchanged. The correlation between Na+t and Na+e ADCs was observed because of high Na+e concentration. Similarly, the correlation between water and Na+i ADCs was observed because cells occupy 80% of the tissue space in the skeletal muscle. Ischemia also caused an increase in the Na+i and an equal decrease in Na+e signal intensity due to cessation of Na+/K+-ATPase function. (c) 2008 Wiley-Liss, Inc.
Chittavong, Malavanh; Jansson, Anna; Lindberg, Jan Erik
2013-10-01
Thirty castrated male Moo Lath pigs (6-8 weeks of age) were used in a 15-week growth trial to study the effect of high dietary sodium chloride (NaCl) content on feed and water intake, performance, sodium (Na) and potassium (K) balance, and plasma aldosterone concentration. The pigs were randomly allocated (ten per treatment) to diets containing 0.24 % Na (Na0.24), 0.28 % Na (Na0.28), and 0.32 % Na (Na0.32) per kg diet. Feed and water was provided ad libitum, and water consumption, feed offered, and feed residues were recorded daily. Every third week, the pigs were weighed, blood samples were collected, and a 3-day total collection of urine and feces was performed. Water intake was higher (P = 0.001) in pigs fed with diets Na0.28 (3.7 L/day) and Na0.32 (3.9 L/day) than in pigs fed with diet Na0.24 (3.4 L/day), and dry matter (DM) intake was higher on diet Na0.32 (P = 0.041) than on the other diets. The average daily body weight (BW) gain was higher on diet Na0.32 than on the other diets (P = 0.031). The feed conversion ratio (in kilogram feed DM to kilogram BW gain) was 4.6, 4.6, and 4.1 on treatments Na0.24, Na0.28, and Na0.32, respectively (P = 0.14). The highest Na balance was observed on diet Na0.32 followed by diets Na0.28 and Na0.24 (P < 0.001), while there was no treatment-related pattern for the K balance. The Na/K ratio in feces and urine increased (P < 0.001), and the K/Na ratio in feces (P < 0.001) decreased with increasing Na content in the diet. Plasma aldosterone concentration decreased (P < 0.001) with increasing dietary content of Na. These results indicate that high NaCl intake and free access to water will increase Na balance but do not negatively influence feed intake and performance of growing local pigs.
Metal Residue Deposition from Military Pyrotechnic Devices and Field Sampling Guidance
2012-05-01
0.002 26.4 NA 0.082 Cerium none given NA 0.002 NA NA Chromium Oxide 1308-38-9 NA NA NA 0.015 Cobalt Naphthenate 61789-51-3 NA NA NA 0.017 Copper...the 1980s, the constituents in the whistling booby trap simulators included 73% potassium perchlorate, 24% gallic acid , and 3 % red gum (McIntyre...Test 3, MI snow sample, Rep 3 M21 Flash Artillery Simulator 50 3785.8 2/5/10 All – indicates the entire volume of stained snow was removed . MI
High pressure structural stability of the Na-Te system
NASA Astrophysics Data System (ADS)
Wang, Youchun; Tian, Fubo; Li, Da; Duan, Defang; Xie, Hui; Liu, Bingbing; Zhou, Qiang; Cui, Tian
2018-03-01
The ab initio evolutionary algorithm is used to search for all thermodynamically stable Na-Te compounds at extreme pressure. In our calculations, several new structures are discovered at high pressure, namely, Imma Na2Te, Pmmm NaTe, Imma Na8Te2 and P4/mmm NaTe3. Like the known structures of Na2Te (Fm-3m, Pnma and P63/mmc), the Pmmm NaTe, Imma Na8Te2 and P4/mmm NaTe3 structures also show semiconductor properties with band-gap decreases when pressure increased. However, we find that the band-gap of Imma Na2Te structure increases with pressure. We presume that the result may be caused by the increasing of splitting between Te p states and Na s, Na p and Te d states. Furthermore, we think that the strong hybridization between Na p state and Te d state result in the band gap increasing with pressure.
Thermal Aspects of Future Spacecraft Thermal Management Systems.
1986-07-01
eutectic salt ) (278 278) (168) (n-a n-a) (0.78 0.78) (2290 2290) (inexpensive))) (95.4 % NaNO3 - 4.6 % NaCl) (inorganic eutectic salt ) (297 297) (178) (n-a...n-a) (0.69 0.69) (2260 2260) (inexpensive))) (69.9 % CaC12 - 30.1 % NaCI) (inorganic eutectic salt ) (490 490) (233) (n-a n-a) (4 4) (2400 2400...inexpensive))) (46.2 % KC1 - 29.9 X CaCI2 -23.9 X NaCi) (inorganic eutectic salt ) (515 515) (265) (n-a n-a) (3.8 3.8) (2160 2160) (inexpensive))) (79
Silva, E N; Silveira, J A G; Rodrigues, C R F; Viégas, R A
2015-09-01
This study assessed the capacity of Jatropha curcas to physiologically adjust to salinity. Seedlings were exposed to increasing NaCl concentrations (25, 50, 75 and 100 mm) for 15 days. Treatment without NaCl was adopted as control. Shoot dry weight was strongly reduced by NaCl, reaching values of 35% to 65% with 25 to 100 mm NaCl. The shoot/root ratio was only affected with 100 mm NaCl. Relative water content (RWC) increased only with 100 mm NaCl, while electrolyte leakage (EL) was much enhanced with 50 mm NaCl. The Na(+) transport rate to the shoot was more affected with 50 and 100 mm NaCl. In parallel, Cl(-) transport rate increased with 75 and 100 mm NaCl, while K(+) transport rate fell from 50 mm to 100 mm NaCl. In roots, Na(+) and Cl(-) transport rates fell slightly only in 50 mm (to Na(+)) and 50 and 100 mm (to Cl(-)) NaCl, while K(+) transport rate fell significantly with increasing NaCl. In general, our data demonstrate that J. curcas seedlings present changes in key physiological processes that allow this species to adjust to salinity. These responses are related to accumulation of Na(+) and Cl(-) in leaves and roots, K(+)/Na(+) homeostasis, transport of K(+) and selectivity (K-Na) in roots, and accumulation of organic solutes contributing to osmotic adjustment of the species. © 2015 German Botanical Society and The Royal Botanical Society of the Netherlands.
The system Na2CO3-CaCO3 at 3 GPa
NASA Astrophysics Data System (ADS)
Podborodnikov, Ivan V.; Shatskiy, Anton; Arefiev, Anton V.; Rashchenko, Sergey V.; Chanyshev, Artem D.; Litasov, Konstantin D.
2018-04-01
It was suggested that alkali-alkaline earth carbonates may have a substantial role in petrological processes relevant to metasomatism and melting of the Earth's mantle. Because natrite, Na2CO3, Na-Ca carbonate (shortite and/or nyerereite), and calcite, CaCO3, have been recently reported from xenoliths of shallow mantle (110-115 km) origin, we performed experiments on phase relations in the system Na2CO3-CaCO3 at 3 GPa and 800-1300 °C. We found that the system has one intermediate compound, Na2Ca3(CO3)4, at 800 °C, and two intermediate compounds, Na2Ca(CO3)2 and Na2Ca3(CO3)4, at 850 °C. CaCO3 crystals recovered from experiments at 950 and 1000 °C are aragonite and calcite, respectively. Maximum solid solution of CaCO3 in Na2CO3 is 20 mol% at 850 °C. The Na-carbonate-Na2Ca(CO3)2 eutectic locates near 860 °C and 56 mol% Na2CO3. Na2Ca(CO3)2 melts incongruently near 880 °C to produce Na2Ca3(CO3)4 and a liquid containing about 51 mol% Na2CO3. Na2Ca3(CO3)4 disappears above 1000 °C via incongruent melting to calcite and a liquid containing about 43 mol% Na2CO3. At 1050 °C, the liquid, coexisting with Na-carbonate, contains 87 mol% Na2CO3. Na-carbonate remains solid up to 1150 °C and melts at 1200 °C. The Na2CO3 content in the liquid coexisting with calcite decreases to 15 mol% as temperature increases to 1300 °C. Considering the present and previous data, a range of the intermediate compounds on the liquidus of the Na2CO3-CaCO3 join changes as pressure increases in the following sequence: Na2Ca(CO3)2 (0.1 GPa) → Na2Ca(CO3)2, Na2Ca3(CO3)4 (3 GPa) → Na4Ca(CO3)3, Na2Ca3(CO3)4 (6 GPa). Thus, the Na2Ca(CO3)2 nyerereite stability field extends to the shallow mantle pressures. Consequently, findings of nyerereite among daughter phases in the melt inclusions in olivine from the sheared garnet peridotites are consistent with their mantle origin.
Selective retransplant after graft loss to nonadherence: success with a second chance.
Dunn, T B; Browne, B J; Gillingham, K J; Kandaswamy, R; Humar, A; Payne, W D; Sutherland, D E R; Matas, A J
2009-06-01
Nonadherence (NA) is a difficult posttransplant problem that can lead to graft loss. A retransplant is controversial because of a fear of recurrent NA. We reviewed our center's data base and identified 114 kidney recipients who lost their graft to overt NA; of this group, 35 (31%) underwent a retransplant after a thorough reevaluation. We compared this NA retransplant group to a control group of second transplant recipients who did not lose their first graft to overt NA (non-NA) (n = 552). After 8 years of follow-up, we found no significant differences between the groups in actuarial graft or patient survival rates, renal function, or the incidence of biopsy-proven chronic rejection. However, 5 of 35 (14%) NA recipients versus 10 of 552 (2%) non-NA recipients lost their retransplant to NA (p = 0.0001). Twenty of 35 (57%) of the NA group exhibited repeat NA behavior after retransplant. We conclude that prior graft loss to NA is associated with increased graft loss to NA after retransplant. However, the majority of NA retransplant recipients did well-with overall long-term outcomes similar to those of the non-NA group. With careful patient selection and aggressive intervention, prior overt NA should not be an absolute contraindication to retransplantation.
Lee, Jaegi; Lee, Yongwon; Lee, Jeongmin; Lee, Sang-Min; Choi, Jeong-Hee; Kim, Hyungsub; Kwon, Mi-Sook; Kang, Kisuk; Lee, Kyu Tae; Choi, Nam-Soon
2017-02-01
We present an ultraconcentrated electrolyte composed of 5 M sodium bis(fluorosulfonyl)imide in 1,2-dimethoxyethane for Na metal anodes coupled with high-voltage cathodes. Using this electrolyte, a very high Coulombic efficiency of 99.3% at the 120th cycle for Na plating/stripping is obtained in Na/stainless steel (SS) cells with highly reduced corrosivity toward Na metal and high oxidation durability (over 4.9 V versus Na/Na + ) without corrosion of the aluminum cathode current collector. Importantly, the use of this ultraconcentrated electrolyte results in substantially improved rate capability in Na/SS cells and excellent cycling performance in Na/Na symmetric cells without the increase of polarization. Moreover, this ultraconcentrated electrolyte exhibits good compatibility with high-voltage Na 4 Fe 3 (PO 4 ) 2 (P 2 O 7 ) and Na 0.7 (Fe 0.5 Mn 0.5 )O 2 cathodes charged to high voltages (>4.2 V versus Na/Na + ), resulting in outstanding cycling stability (high reversible capacity of 109 mAh g -1 over 300 cycles for the Na/Na 4 Fe 3 (PO 4 ) 2 (P 2 O 7 ) cell) compared with the conventional dilute electrolyte, 1 M NaPF 6 in ethylene carbonate/propylene carbonate (5/5, v/v).
China Macroeconomic: Documentation Data Banks. Volume 3. Foreign Trade.
1984-11-15
1983 data from Chlnese "Cmtan, Statistics," Econmic Infomation and Agency, THoE ong Pr ious years from CIA "International Trade Statistics" Load fram...204,097 145,564 515,062 1984 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6 Sources, see below 19F, 1983 data from Chinese "Customs Statistics," Econmic ...Statistics," EconmIc Information and Agency, F org Previous years fran CIA "Internationl Trade Statistics" Load from rw 12 to row 54 -.96 - A B C D E F G H
Impact of a potential glycosylation site at neuraminidase amino acid 264 of influenza A/H9N2 virus.
Shao, Hongxia; Zhou, Xiaoxiang; Fan, Zhonglei; Wan, Zhimin; Qian, Kun; Perez, Daniel; Qin, Aijian; Ye, Jianqiang
2016-11-30
To determine the role of the potential glycosylation site NA264N, which has been shown to be prevalent in recent Chinese H9N2 isolates, four reverse genetic viruses, rgWS1-NA264N, rgWS1-NA264H, rgBJ-NA264H and rgBJ-NA264N, were rescued. Growth kinetics showed that viruses with NA264H grew faster than viruses with NA264N. Mouse studies revealed that rgBJ-NA264H replicated to a significantly higher titer than rgBJ-NA264N at 3dpi. Notably, in contact chickens, rgBJ-NA264H and rgWS1-NA264H shed significantly more virus than rgBJ-NA264N at 6dpi from the larynx and rgWS1-NA264N at 4dpi from the cloaca, respectively. The present study demonstrates that NA264N affects viral replication of H9N2. Copyright © 2016 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
He, Mingfu; Lau, Kah Chun; Ren, Xiaodi
Alkali metal-oxygen batteries are of great interests for energy storage because of their unparalleled theoretical energy densities. Particularly attractive is the emerging Na-O 2 battery because of the formation of superoxide as the discharge product. Dimethyl sulfoxide (DMSO) is a promising solvent for this battery but its instability towards Na makes it impractical in the Na-O 2 battery. Here in this paper, we report the enhanced stability of Na in DMSO solutions containing concentrated sodium trifluoromethanesulfonimide (NaTFSI) salts (>3molkg -1). Raman spectra of NaTFSI/DMSO electrolytes and abinitio molecular dynamics simulation reveal the Na + solvation number in DMSO and themore » formation of Na(DMSO) 3(TFSI)-like solvation structure. The majority of DMSO molecules solvating Na + in concentrated solutions reduces the available free DMSO molecules that can react with Na and renders the TFSI anion decomposition, which protects Na from reacting with the electrolyte. Using these concentrated electrolytes, Na-O 2 batteries can be cycled forming sodium superoxide (NaO 2) as the sole discharge product with improved long cycle life, highlighting the beneficial role of concentrated electrolytes for Na-based batteries.« less
2010 Department of Defense (DoD) Chemical and Biological Defense Program (CBDP) Portfolio
2010-03-01
a new oxime and (2) obtaining approval for use of pyridostigmine bromide , the component of Soman Nerve Agent Pretreatment Pyridostigmine (SNAPP) for...Pralidoxime Chloride Autoinjector N/A 6505-01-125-3248 11704-620-01 N/A DLA 8 Pyridostigmine Bromide Tabs USP 30 mg I.S. (SNAPP) N/A 6505-01-178-7903 N...Soman Nerve Agent Pretreatment Pyridostigmine (SNAPP) N/A 6505-01-483-7162 N/A N/A N/A N/A Vaccines Anthrax Vaccine Adsorbed (AVA) N/A 6505-01-399
Biel, Philippe; Mohn, Dirk; Attin, Thomas; Zehnder, Matthias
2017-04-01
A clinically useful all-in-one endodontic irrigant with combined proteolytic and decalcifying properties is still elusive. In this study, the chemical effects of dissolving the tetrasodium salts of 1-hydroxyethane 1,1-diphosphonic acid (Na 4 HEDP) or Na 4 EDTA directly in sodium hypochlorite (NaOCl) irrigants in polypropylene syringes were assessed during the course of 1 hour. The solubility of the salts in water was determined. Their compatibility with 1% and 5% NaOCl was measured by iodometric titration and in a calcium complexation experiment by using a Ca 2+ -selective electrode. The salts dissolved within 1 minute. The dissolution maximum of Na 4 HEDP in water (wt/total wt) was 44.6% ± 1.6%. The corresponding dissolution maximum of Na 4 EDTA was 38.2% ± 0.8%. Na 4 HEDP at 18% in 5% NaOCl caused a mere loss of 16% of the initially available chlorine during 1 hour. In contrast, a corresponding mixture between NaOCl and the Na 4 EDTA salt caused 95% reduction in available chlorine after 1 minute. Mixtures of 3% Na 4 EDTA with 1% NaOCl were more stable, but only for 30 minutes. Na 4 HEDP lost 24% of its calcium complexation capacity after 60 minutes. The corresponding loss for Na 4 EDTA was 34%. The compatibility and solubility of particulate Na 4 HEDP with/in NaOCl solutions are such that these components can be mixed and used for up to 1 hour. In contrast, short-term compatibility of the Na 4 EDTA salt with NaOCl solutions was considerably lower, decreasing at higher concentrations of either compound. Especially for Na 4 HEDP but also for Na 4 EDTA, the NaOCl had little effect on calcium complexation. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
Apical membrane permeability and kinetic properties of the sodium pump in rabbit urinary bladder.
Lewis, S A; Wills, N K
1983-08-01
Previous studies have shown that aldosterone stimulates the rate of Na+ transport across the rabbit urinary bladder epithelium by increasing the apical membrane permeability to Na+. Paradoxically, ion-sensitive and conventional micro-electrode measurements demonstrated that intracellular Na+ activity aiNa+ was essentially unchanged by aldosterone, i.e. aiNa+ was constant regardless of the rate of Na+ transport. The present study was designed to resolve this apparent contradiction. The effects of elevated, endogenous aldosterone levels produced by low-Na+ diet (Lewis & Diamond, 1976) on urinary bladder Na+ transport were investigated in vitro using Ussing-type chambers and intracellular conventional and ion-sensitive microelectrodes. Apical membrane selectivity and kinetics of the Na+ pump were assessed as a function of hormone stimulation. The aldosterone-stimulated increase in Na+ transport was accounted for by increases in both the relative selective permeability of the apical membrane to Na+ and an increase in its absolute Na+ permeability. The kinetics of the Na+ pump were evaluated electrically by loading the cells with Na+ (monitored with Na+-sensitive micro-electrodes) or alternatively by manipulating serosal solution K+ concentration and measuring changes in the basolateral membrane electromotive forces and resistance. From these measurements the current generated by the pump was calculated as a function of intracellular Na+ or extracellular K+. The kinetics of the pump were not altered by aldosterone. A model of highly co-operative binding estimated Km for Na+ as 14.2 mM and 2.3 mM for K+. Hill coefficients for these ions were 2.8 and 1.8, respectively, consistent with a pump stoichiometry of 3 Na+ to 2 K+. The kinetic properties of the Na-K pump indicate that physiological levels of aiNa+ are poised at the foot of a step kinetic curve which energetically favours Na+ extrusion.
Chapman, R A; Coray, A; McGuigan, J A
1983-01-01
A method for mounting and rapidly perfusing small ventricular trabeculae (diameter around 250 micron) from either ferret or guinea-pig is described. Tension, membrane potential (Em) and intracellular Na activity (aiNa) were measured. aiNa was measured using Na-sensitive micro-electrodes. At room temperature (22-26 degrees C), [Na]o 155 mmol/l and [Ca]o 5.4 mmol/l, aiNa was 10.9 mmol/l +/- S.D. 4.2 mmol/l (n = 148). When [Na]o was reduced from 155 to 1.5 mmol/l contractures developed. These were about twitch height in guinea-pig but less than the twitch height in ferret. Associated with the development of the contracture there was a decrease in aiNa. The aiNa halved within 30 s. The decrease in aiNa was not influenced by changing pHo from 7.4 to 9.5, K-free solution or strophanthidin 50 mumol/l and was not passive since, even when the [Na]o was 1.5 mmol/l, the driving force for Na ions remained inward. The aiNa decreased if [Ca]o was increased and [Na]o decreased or vice versa. On the basis of these findings it is concluded that the decrease in aiNa is mainly due to Na/Ca exchange. Despite the large decrease in aiNa the [Ca]i, as monitored by tension changes, hardly increased. Since Ca uptake does occur in Na-free conditions in heart muscle it is proposed that the mitochondria take up Ca ions and so prevent an excessive rise in cytoplasmic Ca. Strophanthidin increased both aiNa and the withdrawal contracture, but collected results from a number of experiments showed no clear correlation between the initial aiNa and contracture amplitude. Strophanthidin may, therefore, have actions additional to increasing aiNa. PMID:6644617
Spatial and mineralogic variation of Na-Ca alteration in Laramide porphyry systems of Arizona
NASA Astrophysics Data System (ADS)
Runyon, S.; Seedorff, E.; Barton, M. D.; Mazdab, F. K.; Lecumberri-Sanchez, P.; Steele-MacInnis, M.
2017-12-01
Na-Ca alteration is characterized by the metasomatic addition of Ca ± Na and the loss of K. Minor volumes of Na-Ca alteration in Laramide porphyry systems develops from 3 to 8 km paleodepth. Mineral assemblages, mineral compositions, hydrogen isotopes, whole-rock analyses, and reconnaissance fluid inclusion characteristics have been documented for Na-Ca alteration in Laramide porphyry systems such as Tea Cup and Sierrita. Volumetrically minor Na-Ca alteration in Laramide porphyry systems documented in this study commonly takes the form of one of three mineral assemblages: albite-epidote-chlorite, Na-plagioclase-actinolite ± epidote, and garnet- or diopside-stable Na-plagioclase-actinolite ± epidote. These different Na-Ca mineral assemblages have broad spatial relationships, from shallow albite-chlorite-epidote to deeper Na-plagioclase-actinolite within a given district. Hydrogen isotope data on Na-Ca alteration minerals shows consistently distinct δD compositions of Na-Ca alteration minerals compared to igneous minerals in a given district. Further, calculated hydrogen isotope composition of fluids in equilibrium with Na-Ca alteration minerals are consistently enriched in δD compared to magmatic-hydrothermal fluids. Whole-rock analyses show consistent losses of K and variable addition of Na and Ca across different Na-Ca alteration assemblages. Na-Ca alteration has been well documented associated with the Jurassic arc. Previous studies demonstrated through mass balance, timing and spatial relationships, isotopic, and fluid inclusion studies that Na-Ca alteration associated with the Jurassic arc likely formed from the circulation of external, highly saline, non-magmatic fluids (e.g., Battles and Barton, 1995; Dilles et al., 1995). Na-Ca alteration documented in Laramide systems is generally similar to Na-Ca alteration documented along the Jurassic arc in mineral assemblages, compositions, and timing, but the volume of Na-Ca alteration in the Laramide systems is small as compared to the voluminous Na-Ca alteration documented in systems associated with the Jurassic arc.
Functional identification and characterization of sodium binding sites in Na symporters
Loo, Donald D. F.; Jiang, Xuan; Gorraitz, Edurne; Hirayama, Bruce A.; Wright, Ernest M.
2013-01-01
Sodium cotransporters from several different gene families belong to the leucine transporter (LeuT) structural family. Although the identification of Na+ in binding sites is beyond the resolution of the structures, two Na+ binding sites (Na1 and Na2) have been proposed in LeuT. Na2 is conserved in the LeuT family but Na1 is not. A biophysical method has been used to measure sodium dissociation constants (Kd) of wild-type and mutant human sodium glucose cotransport (hSGLT1) proteins to identify the Na+ binding sites in hSGLT1. The Na1 site is formed by residues in the sugar binding pocket, and their mutation influences sodium binding to Na1 but not to Na2. For the canonical Na2 site formed by two –OH side chains, S392 and S393, and three backbone carbonyls, mutation of S392 to cysteine increased the sodium Kd by sixfold. This was accompanied by a dramatic reduction in the apparent sugar and phlorizin affinities. We suggest that mutation of S392 in the Na2 site produces a structural rearrangement of the sugar binding pocket to disrupt both the binding of the second Na+ and the binding of sugar. In contrast, the S393 mutations produce no significant changes in sodium, sugar, and phlorizin affinities. We conclude that the Na2 site is conserved in hSGLT1, the side chain of S392 and the backbone carbonyl of S393 are important in the first Na+ binding, and that Na+ binding to Na2 promotes binding to Na1 and also sugar binding. PMID:24191006
Sodium uptake in different life stages of crustaceans: the water flea Daphnia magna Strauss.
Bianchini, Adalto; Wood, Chris M
2008-02-01
The concentration-dependent kinetics and main mechanisms of whole-body Na+ uptake were assessed in neonate and adult water flea Daphnia magna Strauss acclimated to moderately hard water (0.6 mmol l(-1) NaCl, 1.0 mmol l(-1) CaCO3 and 0.15 mmol l(-1) MgSO4.7H2O; pH 8.2). Whole-body Na+ uptake is independent of the presence of Cl(-) in the external medium and kinetic parameters are dependent on the life stage. Adults have a lower maximum capacity of Na+ transport on a mass-specific basis but a higher affinity for Na+ when compared to neonates. Based on pharmacological analyses, mechanisms involved in whole-body Na+ uptake differ according to the life stage considered. In neonates, a proton pump-coupled Na+ channel appears to play an important role in the whole-body Na+ uptake at the apical membrane. However, they do not appear to contribute to whole-body Na+ uptake in adults, where only the Na+ channel seems to be present, associated with the Na+/H+ exchanger. In both cases, carbonic anhydrase contributes by providing H+ for the transporters. At the basolateral membrane of the salt-transporting epithelia of neonates, Na+ is pumped from the cells to the extracellular fluid by a Na+, K+-ATPase and a Na+/Cl(-) exchanger whereas K+ and Cl(-) move through specific channels. In adults, a Na+/K+/2Cl(-) cotransporter replaces the Na+/Cl(-) exchanger. Differential sensitivity of neonates and adults to iono- and osmoregulatory toxicants, such as metals, are discussed with respect to differences in whole-body Na+ uptake kinetics, as well as in the mechanisms of Na+ transport involved in the whole-body Na+ uptake in the two life stages.
Zhang, Wei; Zhou, Zhen; An, Ying; Du, Silu; Ruan, Danian; Zhao, Chengyue; Ren, Ning; Tian, Xiaoce
2017-07-01
Simultaneous zeolites regeneration and nitrogen removal were investigated by using a mixed solution of NaClO and NaCl (NaClO-NaCl solution), and effects of the regenerant on ammonium removal performance and textural properties of zeolites were analyzed by long-term adsorption and regeneration operations. Mixed NaClO-NaCl solution removed more NH 4 + exchanged on zeolites and converted more of them to nitrogen than using NaClO or NaCl solution alone. Response surface methodological analysis indicated that molar ratio of hypochlorite and nitrogen (ClO - /N), NaCl concentration and pH value all had significant effects on zeolites regeneration and NH 4 + conversion to nitrogen, and the optimum condition was obtained at ClO - /N of 1.75, NaCl concentration of 20 g/L and pH of 10.0. Zeolites regenerated by mixed NaClO-NaCl solution showed higher ammonium adsorption rate and lower capacity than unused zeolites. Zeolites and the regeneration solution were both effective even after 20 cycles of use. Composition and morphological analysis revealed that the main mineral species and surface morphology of zeolites before and after NaClO-NaCl regeneration were unchanged. Textural analysis indicated that NaClO-NaCl regeneration leads to an increased surface area of zeolites, especially the microporosity. The results indicated that NaClO-NaCl regeneration is an attractive method to achieve sustainable removal of nitrogen from wastewater through zeolite. Copyright © 2017 Elsevier Ltd. All rights reserved.
Chao, Dongman; He, Xiaozhou; Yang, Yilin; Bazzy-Asaad, Alia; Lazarus, Lawrence H; Balboni, Gianfranco; Kim, Dong H; Xia, Ying
2012-08-01
Activation of delta-opioid receptors (DOR) is neuroprotective against hypoxic/ischemic injury in the cortex, which is at least partially related to its action against hypoxic/ischemic disruption of ionic homeostasis that triggers neuronal injury. Na(+) influx through TTX-sensitive voltage-gated Na(+) channels may be a main mechanism for hypoxia-induced disruption of K(+) homeostasis, with DOR activation attenuating the disruption of ionic homeostasis by targeting voltage-gated Na(+) channels. In the present study we examined the role of DOR in the regulation of Na(+) influx in anoxia and simulated ischemia (oxygen-glucose deprivation) as well as the effect of DOR activation on the Na(+) influx induced by a Na(+) channel opener without anoxic/ischemic stress and explored a potential PKC mechanism underlying the DOR action. We directly measured extracellular Na(+) activity in mouse cortical slices with Na(+) selective electrodes and found that (1) anoxia-induced Na(+) influx occurred mainly through TTX-sensitive Na(+) channels; (2) DOR activation inhibited the anoxia/ischemia-induced Na(+) influx; (3) veratridine, a Na(+) channel opener, enhanced the anoxia-induced Na(+) influx; this could be attenuated by DOR activation; (4) DOR activation did not reduce the anoxia-induced Na(+) influx in the presence of chelerythrine, a broad-spectrum PKC blocker; and (5) DOR effects were blocked by PKCβII peptide inhibitor, and PKCθ pseudosubstrate inhibitor, respectively. We conclude that DOR activation inhibits anoxia-induced Na(+) influx through Na(+) channels via PKC (especially PKCβII and PKCθ isoforms) dependent mechanisms in the cortex. Copyright © 2012 Elsevier Inc. All rights reserved.
Asaro, Fioretta; Feruglio, Luigi; Galantini, Luciano; Nardelli, Alessia
2013-02-15
The growth of the aggregates of the dihydroxylated bile salt sodium taurodeoxycholate (NaTDC) upon NaCl addition and the involvement of the counterion were investigated by NMR spectroscopy of monoatomic ionic species. (23)Na T(1) values from 0.015, 0.100, and 0.200 mol kg(-1) NaTDC solutions in D(2)O, at variable NaCl content, proved to be sensitive to the transition from primary to secondary aggregates, which occurs in the former sample, and to intermicellar interaction. Some (79)Br NMR measurements were performed on a 0.100 mol kg(-1) NaTDC sample added by NaBr in place of NaCl for comparison purposes. The (23)Na, (35)Cl, and (37)Cl double quantum filtered (DQF) patterns, from the 0.100 mol kg(-1) NaTDC sample, and (23)Na ones also from the 0.200 mol kg(-1) NaTDC one, in the presence of 0.750 mol kg(-1) NaCl, are a clear manifestation of motional anisotropy. Moreover, the DQF spectra of (23)Na and (37)Cl, which possess close quadrupole moments, display a striking similarity. The DQF lineshapes were simulated exploiting the Scilab environment to obtain an estimate of the residual quadrupole splitting magnitude. These results support the description of NaTDC micelles as cylindrical aggregates, strongly interacting at high ionic strengths, and capable of association with added electrolytes. Copyright © 2012 Elsevier Inc. All rights reserved.
Kinetic properties of the sodium-calcium exchanger in rat brain synaptosomes.
Fontana, G; Rogowski, R S; Blaustein, M P
1995-01-01
1. The kinetic properties of the internal Na+ (Na+i)- dependent 45Ca2+ influx and external Na+ (Na+o)-dependent 45Ca2+ efflux were determined in isolated rat brain nerve terminals (synaptosomes) under conditions which the concentrations of internal Na+ ([Na+]i), external Na+ ([Na+]o), external Ca2+ (Ca2+]o), and external K+ ([K+]o) were varied. Both fluxes are manifestations of Na(+)-Ca2+ exchange. 2. Ca2+ uptake was augmented by raising [Na+]i and / or lowering [Na+]o. The increase in Ca2+ uptake induced by removing external Na+ was, in most instances, quantitatively equal to the Na+i-dependent Ca2+ uptake. 3. The Na+i-dependent Ca2+ uptake (measured at 1 s) was activated with an apparent half-maximal [Ca2+]o (KCa(o)) of about 0.23 mM. External Na+ inhibited the uptake in a non- competitive manner: increasing [Na+]o from 4.7 to 96 mM reduced the maximal Na+(i)-dependent Ca2+ uptake but did not affect KCa(o). 4. The inhibition of Ca2+ uptake by Na+o was proportional to ([Na+]o)2, and had a Hill coefficient (nH) of approximately 2.0. The mean apparent half-maximal [Na+]o for inhibition (KI(Na)) was about 60mM, and was independent of [Ca2+]o between 0.1 and 1.2mM; this, too, is indicative of non-competitive inhibition. 5. Low concentrations of alkali metal ions (M+) in the medium, including Na+, stimulated the Na+i-dependent uptake. The external Na+ and K+ concentrations required for apparent half-maximal activation (KM(Na) and KM(K), respectively) were 0.12 and 0.10mM. Thus, the relationship between Ca2+ uptake and [Na+]o was biphasic: uptake was stimulated by [Na+]o < or = 10 mM, and inhibited by higher [Na+]o. 6. The calculated maximal Na+i-dependent Ca2+ uptake (Jmax) was about 1530 pmol (mg protein) -1s-1 at 30 degrees C saturating [Ca2+]o and external M+ concentration ([M+]o), and with negligible inhibition by external Na+. 7. Internal Na+ activated the Ca2+ uptake with an apparent half-maximal concentration (KNa(i)) of about 20 mM and a Hill coefficient, nH, of approximately 3.0. 8. The Jmax for the Na+o-dependent efflux of Ca2+ from 45Ca(2+)-loaded synaptosomes treated with carbonyl cyanide p-trifluormethoxy-phenylhydrazone (FCCP) and caffeine (to release stored Ca2+ and raise the internal Ca2+ concentration ([Ca2+]i) was about 1800-2000 pmol (mg protein -1s-1 at 37 degrees C. 9. When the membrane potential (Vm) was reduced (depolarized) by increasing [K+]o, the Na+i-dependent Ca2+ influx increased, and the Na+o-dependent Ca2+ efflux declined. Both fluxes changed about 2-fold per 60 mV change in Vm. This voltage sensitivity corresponds to the movement of one elementary charge through about 60% of the membrane electric field. The symmetry suggests that the voltage-sensitive step is reversible. 10. The Jmax values for both Ca2P influx and efflux correspond to a Na+-Ca2+ exchange-mediated flux of about 425-575 jumol Ca2P (1 cell water)-' s-' or a turnover of about one quarter of the total synaptosome Ca2P in 1 s. We conclude that the Na+-Ca2P exchanger may contribute to Ca2P entry during nerve terminal depolarization; it is likely to be a major mechanism mediating Ca2P extrusion during subsequent repolarization and recovery. PMID:7666363
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-15
.... The types of ordnances proposed for use at BT-9 and BT- 11 include small arms, large arms, bombs...) 48 48 4.8 Rockets--5.0'' (live) 20 20 15.0 Rockets--2.75'' and 5'' (inert) 876 NA N/A Bombs and G911 grenades (live) 0 NA 0.5 Bombs and grenades (inert) 4,199 NA NA Missile--TOW 0 NA NA Missile--Hellfire 0 NA...
Sodium iron hexacyanoferrate with high Na content as a Na-rich cathode material for Na-ion batteries
DOE Office of Scientific and Technical Information (OSTI.GOV)
You, Ya; Yu, Xi -Qian; Yin, Ya -Xia
Owing to the worldwide abundance and low-cost of Na, room-temperature Na-ion batteries are emerging as attractive energy storage systems for large-scale grids. Increasing the Na content in cathode material is one of the effective ways to achieve high energy density. Prussian blue and its analogues (PBAs) are promising Na-rich cathode materials since they can theoretically store two Na ions per formula. However, increasing the Na content in PBAs cathode materials is a big challenge in the current. Here we show that sodium iron hexacyanoferrate with high Na content could be obtained by simply controlling the reducing agent and reaction atmospheremore » during synthesis. The Na content can reach as high as 1.63 per formula, which is the highest value for sodium iron hexacyanoferrate. This Na-rich sodium iron hexacyanoferrate demonstrates a high specific capacity of 150 mA h g -1 and remarkable cycling performance with 90% capacity retention after 200 cycles. Furthermore, the Na intercalation/de-intercalation mechanism is systematically studied by in situ Raman, X-ray diffraction and X-ray absorption spectroscopy analysis for the first time. As a result, the Na-rich sodium iron hexacyanoferrate could function as a plenteous Na reservoir and has great potential as a cathode material toward practical Na-ion batteries.« less
Alparone, Andrea; Librando, Vito
2012-04-01
Structure, IR and Raman spectra of 1-, 2- and 9-nitroanthracene isomers (1-NA, 2-NA and 9-NA) were calculated and analyzed through density functional theory computations using the B3LYP functional with the 6-311+G** basis set. Steric and π-conjugative effects determine the characteristic ONCC dihedral angles, which vary from 0° (2-NA) to 28-29° (1-NA) and 59° (9-NA), influencing the relative order of stability along the series 9-NA<1-NA<2-NA. The spectral regions at wavenumber values>3000 cm(-1) and <1000 cm(-1) little depend on the substituent position. The Raman and IR intensity values of the characteristic symmetric nitro group stretching transition, appearing between 1310 and 1345 cm(-1), are rather sensitive to the position of the substituent, decreasing regularly on passing from the planar to the NO2-rotated isomers (9-NA<1-NA<2-NA). In the medium-energy spectral region (1000-1700 cm(-1)), the number and the relative position of the strongest Raman bands are of potential utility to discriminate the NA isomers. Structural and spectroscopic results suggest that the unknown mutagenic activity of 1-NA is expected to be between that of 9-NA and 2-NA. Copyright © 2011 Elsevier B.V. All rights reserved.
Sodium iron hexacyanoferrate with high Na content as a Na-rich cathode material for Na-ion batteries
You, Ya; Yu, Xi -Qian; Yin, Ya -Xia; ...
2014-10-27
Owing to the worldwide abundance and low-cost of Na, room-temperature Na-ion batteries are emerging as attractive energy storage systems for large-scale grids. Increasing the Na content in cathode material is one of the effective ways to achieve high energy density. Prussian blue and its analogues (PBAs) are promising Na-rich cathode materials since they can theoretically store two Na ions per formula. However, increasing the Na content in PBAs cathode materials is a big challenge in the current. Here we show that sodium iron hexacyanoferrate with high Na content could be obtained by simply controlling the reducing agent and reaction atmospheremore » during synthesis. The Na content can reach as high as 1.63 per formula, which is the highest value for sodium iron hexacyanoferrate. This Na-rich sodium iron hexacyanoferrate demonstrates a high specific capacity of 150 mA h g -1 and remarkable cycling performance with 90% capacity retention after 200 cycles. Furthermore, the Na intercalation/de-intercalation mechanism is systematically studied by in situ Raman, X-ray diffraction and X-ray absorption spectroscopy analysis for the first time. As a result, the Na-rich sodium iron hexacyanoferrate could function as a plenteous Na reservoir and has great potential as a cathode material toward practical Na-ion batteries.« less
Thermodynamic properties of Na2O-SiO2-CaO melts at 1000 to 1100 °C
NASA Astrophysics Data System (ADS)
Neudorf, D. A.; Elliott, J. F.
1980-12-01
The thermodynamic properties of Na2O-SiO2 and Na2O-SiO2-CaO melts have been measured using the galvanic cellbegin{array}{*{20}c} {O_2 (g), (Na_2 O), Pt} \\ {Na_2 O - WO_3 liq} \\ left| begin{gathered} Na^ + \\ β - alumina \\ right| begin{array}{*{20}c} {Pt,(Na_2 O), O_2 (g)} \\ {Na_2 O - SiO_2 - CaO liq} \\ Activities of Na2O were calculated from the reversible emf of the cell. This is possible because the activity of Na2O in the Na2O-WO3 liquid is known from previous work. Data for the binary Na2O-SiO2 system were obtained between 1000 and 1100 °C and for compositions ranging from 25 wt pct to 40 wt pct Na2O. At 1050 °C, Loga_{Na_2 O} varied from approximately 10.2 at 25 wt pct Na2O to approximately -8.3 at 40 wt pct Na2O, the dependence with respect to composition being nearly linear. The Gibbs-Duhem equation was used to calculate the activities of SiO2(s), and the integral mixing properties, G M, HM, and S M, were derived. At the di-silicate composition, G M = -83 kJ/mol, H M = -41 kJ mol and S M = 33 J/mol K at 1000 °C. (Standard states are pure, liquid Na2O and pure, solid tridymite.) The activity data are interpreted in terms of the polymeric nature of silicate melts. Activities of Na2O in the Na2O-CaO-SiO2 system were measured for the 25, 30 and 35 wt pct Na2O binary compositions with up to 10 wt pct CaO added. The addition of CaO caused an increase in the activity of Na2O at constantN_{Na_2 O} /N_{SiO_2 } . The experimental data agree well with the behavior predicted by Richardson’s ternary mixing model.
1988-06-01
Fuseaje mode%, 6/un/im NA 10 10 10 6/10 6/9 6/10 6/10 4/0 NA rigid body / elastic Aerodynamics on NA NA NA NA NA CP CP CP CP NA NA fuselage Pylon CP PR GDOF... motions were cyclic and body modes using the moving-block allowed to decay freely. The body pitch and roll analysis. A complete discussion of the model...conditions. Quick-acting and slow- o acting (self-centering) snubbers were intalled to 0 0 arrest the fuselage motion divergences or co lock 0 0 out body
2006-09-05
NA NA no yes BMAA1128 ABC Transporter 3 GGGAAACGCGAAAC 6 5 yes no BMAA1873 Hypothetical protein 4 No (-C) NA NA no yes BMAA1868 Aconitate hydratase 5...no yes BMAA1868 Aconitate hydratase 3 GTGCTGTC 21 22 no yes BMAA0375 Transcriptional regulator Human Blood 1 TTGGCGC 111 109 no no BMAA1866 Conserved...NA NA no yes BMAA1128 ABC transporter 5 No (-C) NA NA no yes BMAA1868 Aconitate hydratase NA: Not applicable.Page 3 of 11 (page number not for
F-22 Increment 3.2B Modernization (F-22 Inc 3.2B Mod)
2015-12-01
Production Jan 2018 Jan 2018 Jul 2018 Jul 2018 Required Assets Available ( RAA ) Mar 2019 Mar 2019 Sep 2019 Sep 2019 Change Explanations None Notes... RAA is defined as six aircraft and associated support equipment. F-22 Inc 3.2B Mod December 2015 SAR March 23, 2016 16:11:54 UNCLASSIFIED 9...Mar 2016 N/A Jun 2016 RAA N/A Mar 2019 N/A Sep 2019 Total Cost (TY $M) N/A 1584.1 N/A 1542.6 Total Quantity N/A 152 N/A 152 PAUC N/A 10.422 N/A 10.149
Evaluation of Nondestructive Methods for Determining Pavement Thickness
2011-09-01
38, PCC 10.38 10.38 9.57 N/A 39, PCC 11.21 11.21 10.31 N/A 40c*, PCC 8.92 8.92 9.84 N/A SB = stabilized limestone base, PCC = portland cement ...PCC 8.92 8.92 8.07 8.92 SB = stabilized limestone base, PCC = portland cement concrete, and AC = asphalt concrete. * Denotes a test location used as...10.38 N/A N/A 39, PCC 11.21 11.21 N/A N/A 40c*, PCC 8.92 8.92 N/A N/A SB = stabilized limestone base, PCC = portland cement concrete, and AC
Comparison of fluorescence probes for intracellular sodium imaging in prostate cancer cell lines.
Iamshanova, Oksana; Mariot, Pascal; Lehen'kyi, V'yacheslav; Prevarskaya, Natalia
2016-10-01
Sodium (Na + ) ions are known to regulate many signaling pathways involved in both physiological and pathological conditions. In particular, alterations in intracellular concentrations of Na + and corresponding changes in membrane potential are known to be major actors of cancer progression to metastatic phenotype. Though the functionality of Na + channels and the corresponding Na + currents can be investigated using the patch-clamp technique, the latter is rather invasive and a technically difficult method to study intracellular Na + transients compared to Na + fluorescence imaging. Despite the fact that Na + signaling is considered an important controller of cancer progression, only few data using Na + imaging approaches are available so far, suggesting the persisting challenge within the scientific community. In this study, we describe in detail the approach for application of Na + imaging technique to measure intracellular Na + variations in human prostate cancer cells. Accordingly, we used three Na + -specific fluorescent dyes-Na + -binding benzofuran isophthalate (SBFI), CoroNa™ Green (Corona) and Asante NaTRIUM Green-2 (ANG-2). These dyes have been assessed for optimal loading conditions, dissociation constant and working range after different calibration methods, and intracellular Na + sensitivity, in order to determine which probe can be considered as the most reliable to visualize Na + fluctuations in vitro.
Dendrite-Free Sodium-Metal Anodes for High-Energy Sodium-Metal Batteries.
Sun, Bing; Li, Peng; Zhang, Jinqiang; Wang, Dan; Munroe, Paul; Wang, Chengyin; Notten, Peter H L; Wang, Guoxiu
2018-05-31
Sodium (Na) metal is one of the most promising electrode materials for next-generation low-cost rechargeable batteries. However, the challenges caused by dendrite growth on Na metal anodes restrict practical applications of rechargeable Na metal batteries. Herein, a nitrogen and sulfur co-doped carbon nanotube (NSCNT) paper is used as the interlayer to control Na nucleation behavior and suppress the Na dendrite growth. The N- and S-containing functional groups on the carbon nanotubes induce the NSCNTs to be highly "sodiophilic," which can guide the initial Na nucleation and direct Na to distribute uniformly on the NSCNT paper. As a result, the Na-metal-based anode (Na/NSCNT anode) exhibits a dendrite-free morphology during repeated Na plating and striping and excellent cycling stability. As a proof of concept, it is also demonstrated that the electrochemical performance of sodium-oxygen (Na-O 2 ) batteries using the Na/NSCNT anodes show significantly improved cycling performances compared with Na-O 2 batteries with bare Na metal anodes. This work opens a new avenue for the development of next-generation high-energy-density sodium-metal batteries. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Concentrated Electrolyte for the Sodium-Oxygen Battery: Solvation Structure and Improved Cycle Life.
He, Mingfu; Lau, Kah Chun; Ren, Xiaodi; Xiao, Neng; McCulloch, William D; Curtiss, Larry A; Wu, Yiying
2016-12-05
Alkali metal-oxygen batteries are of great interests for energy storage because of their unparalleled theoretical energy densities. Particularly attractive is the emerging Na-O 2 battery because of the formation of superoxide as the discharge product. Dimethyl sulfoxide (DMSO) is a promising solvent for this battery but its instability towards Na makes it impractical in the Na-O 2 battery. Herein we report the enhanced stability of Na in DMSO solutions containing concentrated sodium trifluoromethanesulfonimide (NaTFSI) salts (>3 mol kg -1 ). Raman spectra of NaTFSI/DMSO electrolytes and ab initio molecular dynamics simulation reveal the Na + solvation number in DMSO and the formation of Na(DMSO) 3 (TFSI)-like solvation structure. The majority of DMSO molecules solvating Na + in concentrated solutions reduces the available free DMSO molecules that can react with Na and renders the TFSI anion decomposition, which protects Na from reacting with the electrolyte. Using these concentrated electrolytes, Na-O 2 batteries can be cycled forming sodium superoxide (NaO 2 ) as the sole discharge product with improved long cycle life, highlighting the beneficial role of concentrated electrolytes for Na-based batteries. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Concentrated Electrolyte for the Sodium-Oxygen Battery: Solvation Structure and Improved Cycle Life
He, Mingfu; Lau, Kah Chun; Ren, Xiaodi; ...
2016-11-03
Alkali metal-oxygen batteries are of great interests for energy storage because of their unparalleled theoretical energy densities. Particularly attractive is the emerging Na-O 2 battery because of the formation of superoxide as the discharge product. Dimethyl sulfoxide (DMSO) is a promising solvent for this battery but its instability towards Na makes it impractical in the Na-O 2 battery. Here in this paper, we report the enhanced stability of Na in DMSO solutions containing concentrated sodium trifluoromethanesulfonimide (NaTFSI) salts (>3molkg -1). Raman spectra of NaTFSI/DMSO electrolytes and abinitio molecular dynamics simulation reveal the Na + solvation number in DMSO and themore » formation of Na(DMSO) 3(TFSI)-like solvation structure. The majority of DMSO molecules solvating Na + in concentrated solutions reduces the available free DMSO molecules that can react with Na and renders the TFSI anion decomposition, which protects Na from reacting with the electrolyte. Using these concentrated electrolytes, Na-O 2 batteries can be cycled forming sodium superoxide (NaO 2) as the sole discharge product with improved long cycle life, highlighting the beneficial role of concentrated electrolytes for Na-based batteries.« less
Larsen, Brian Roland; Holm, Rikke; Vilsen, Bente
2016-01-01
Key points Management of glutamate and K+ in brain extracellular space is of critical importance to neuronal function.The astrocytic α2β2 Na+/K+‐ATPase isoform combination is activated by the K+ transients occurring during neuronal activity.In the present study, we report that glutamate transporter‐mediated astrocytic Na+ transients stimulate the Na+/K+‐ATPase and thus the clearance of extracellular K+.Specifically, the astrocytic α2β1 Na+/K+‐ATPase subunit combination displays an apparent Na+ affinity primed to react to physiological changes in intracellular Na+.Accordingly, we demonstrate a distinct physiological role in K+ management for each of the two astrocytic Na+/K+‐ATPase β‐subunits. Abstract Neuronal activity is associated with transient [K+]o increases. The excess K+ is cleared by surrounding astrocytes, partly by the Na+/K+‐ATPase of which several subunit isoform combinations exist. The astrocytic Na+/K+‐ATPase α2β2 isoform constellation responds directly to increased [K+]o but, in addition, Na+/K+‐ATPase‐mediated K+ clearance could be governed by astrocytic [Na+]i. During most neuronal activity, glutamate is released in the synaptic cleft and is re‐absorbed by astrocytic Na+‐coupled glutamate transporters, thereby elevating [Na+]i. It thus remains unresolved whether the different Na+/K+‐ATPase isoforms are controlled by [K+]o or [Na+]i during neuronal activity. Hippocampal slice recordings of stimulus‐induced [K+]o transients with ion‐sensitive microelectrodes revealed reduced Na+/K+‐ATPase‐mediated K+ management upon parallel inhibition of the glutamate transporter. The apparent intracellular Na+ affinity of isoform constellations involving the astrocytic β2 has remained elusive as a result of inherent expression of β1 in most cell systems, as well as technical challenges involved in measuring intracellular affinity in intact cells. We therefore expressed the different astrocytic isoform constellations in Xenopus oocytes and determined their apparent Na+ affinity in intact oocytes and isolated membranes. The Na+/K+‐ATPase was not fully saturated at basal astrocytic [Na+]i, irrespective of isoform constellation, although the β1 subunit conferred lower apparent Na+ affinity to the α1 and α2 isoforms than the β2 isoform. In summary, enhanced astrocytic Na+/K+‐ATPase‐dependent K+ clearance was obtained with parallel glutamate transport activity. The astrocytic Na+/K+‐ATPase isoform constellation α2β1 appeared to be specifically geared to respond to the [Na+]i transients associated with activity‐induced glutamate transporter activity. PMID:27231201
NASA Astrophysics Data System (ADS)
Liu, Ruijian; Li, Yongfeng; Yao, Bin; Ding, Zhanhui; Deng, Rui; Zhang, Ligong; Zhao, Haifeng; Liu, Lei
2015-08-01
We report that a band-tail emission at 3.08 eV, lower than near-band-edge energy, is observed in photoluminescence measurements of bulk Na-doped CuAlO2. The band-tail emission is attributed to Na-related defects. Electronic structure calculations based on the first-principles method demonstrate that the donor-acceptor compensated complex of NaAl-2Na i in Na-doped CuAlO2 plays a key role in leading to the band-tail emission and bandgap narrowing. Furthermore, Hall effect measurements indicates that the hole concentration in CuAlO2 is independent on Na doping, which is well understood by the donor-acceptor compensation effect of NaAl-2Na i complex.
Training Impact Analysis for Land Warrior Block II
2006-01-01
maximum W... ... 384 384 instructor requirement - S~ Infantry OSUT STraining company size (25 training companies) NA NA 200•:• LW systems to equip all...Grenade, NA NA 10 M 18 Green SMK C-111 TACTICAL Low Expertise Medium Expertise High Expertise EMPLOYMENT Tasks/Skills Taught No Task Number...Practical Exercise of Tactical Employment on LW Capabilities (Leader Task) G945 Hand Grenade, NA NA 10 M18 Yellow SMK G950 Hand Grenade, NA NA 3 M18 Red SMK
NASA Astrophysics Data System (ADS)
Komwatana, P.; Dinudom, A.; Young, J. A.; Cook, D. I.
1996-07-01
In tight Na+-absorbing epithelial cells, the rate of Na+ entry through amiloride-sensitive apical membrane Na+ channels is matched to basolateral Na+ extrusion so that cell Na+ concentration and volume remain steady. Control of this process by regulation of apical Na+ channels has been attributed to changes in cytosolic Ca2+ concentration or pH, secondary to changes in cytosolic Na+ concentration, although cytosolic Cl- seems also to be involved. Using mouse mandibular gland duct cells, we now demonstrate that increasing cytosolic Na+ concentration inhibits apical Na+ channels independent of changes in cytosolic Ca2+, pH, or Cl-, and the effect is blocked by GDP-β -S, pertussis toxin, and antibodies against the α -subunits of guanine nucleotide-binding regulatory proteins (Go). In contrast, the inhibitory effect of cytosolic anions is blocked by antibodies to inhibitory guanine nucleotide-binding regulatory proteins (Gi1/Gi2. It thus appears that apical Na+ channels are regulated by Go and Gi proteins, the activities of which are controlled, respectively, by cytosolic Na+ and Cl-.
Na+/Ca2+ exchange and Na+/K+-ATPase in the heart
Shattock, Michael J; Ottolia, Michela; Bers, Donald M; Blaustein, Mordecai P; Boguslavskyi, Andrii; Bossuyt, Julie; Bridge, John H B; Chen-Izu, Ye; Clancy, Colleen E; Edwards, Andrew; Goldhaber, Joshua; Kaplan, Jack; Lingrel, Jerry B; Pavlovic, Davor; Philipson, Kenneth; Sipido, Karin R; Xie, Zi-Jian
2015-01-01
This paper is the third in a series of reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation–contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on cardiac Na+/Ca2+ exchange (NCX) and Na+/K+-ATPase (NKA). While the relevance of Ca2+ homeostasis in cardiac function has been extensively investigated, the role of Na+ regulation in shaping heart function is often overlooked. Small changes in the cytoplasmic Na+ content have multiple effects on the heart by influencing intracellular Ca2+ and pH levels thereby modulating heart contractility. Therefore it is essential for heart cells to maintain Na+ homeostasis. Among the proteins that accomplish this task are the Na+/Ca2+ exchanger (NCX) and the Na+/K+ pump (NKA). By transporting three Na+ ions into the cytoplasm in exchange for one Ca2+ moved out, NCX is one of the main Na+ influx mechanisms in cardiomyocytes. Acting in the opposite direction, NKA moves Na+ ions from the cytoplasm to the extracellular space against their gradient by utilizing the energy released from ATP hydrolysis. A fine balance between these two processes controls the net amount of intracellular Na+ and aberrations in either of these two systems can have a large impact on cardiac contractility. Due to the relevant role of these two proteins in Na+ homeostasis, the emphasis of this review is on recent developments regarding the cardiac Na+/Ca2+ exchanger (NCX1) and Na+/K+ pump and the controversies that still persist in the field. PMID:25772291
Varecka, L; Peterajová, E; Písová, E
1998-08-14
The properties of the 45Ca2+ influx by human red blood cells (RBC) induced by NaVO3 or NaF were compared. The NaVO3-induced 45Ca2+ influx was slower and less extensive than that induced by NaF. Both processes were saturable with Ca2+. Substitution of Na+ by K+ inhibited the 45Ca2+ influx induced by NaVO3 but stimulated that by NaF. The NaVO3-induced Ca2+ influx was sensitive to nifedipine (IC50 = 50 mol/l), Cu2+ (IC50=9 mol/l), DTNB (5,5'-dithiobis-(dinitrobenzoic acid)) (IC50 = 12 mol/l) (maximal inhibition 16%, 18%, and 28%, respectively, if NaF was used as inducer). On the other hand, tetrodotoxin (TTX) and cyclosporin A inhibited only the NaF-induced 45Ca2+ influx (IC50 = 21 mol/l and 28 mol/l, respectively). Pig RBC, known not to display the NaVO3-induced Ca2+ influx, exhibited Ca2+ influx induced by NaF. The results show that NaVO3 activates the Ca2+ influx via a pathway homologous to the L-type Ca2+ channel while the NaF-induced Ca2+ influx is mediated via the TTX-sensitive Na+ channel in the presence of NaF with possible participation of calcineurin or cyclophilin. Thus, the Gardos effect induced by NaVO3 and NaF represents two phenomena activated by different mechanisms present in the cryptic state in the RBC membrane.
[Effect of NaOH-treatment on dry-thermophilic anaerobic digestion of Spartina alterniflora].
Chen, Guang-Yin; Zheng, Zheng; Chang, Zhi-Zhou; Ye, Xiao-Mei; Luo, Yan
2011-07-01
In order to improve the biotransformation rate of lignocellulosic materials, sodium hydroxide (NaOH) was widely used to pretreat lignocellulosic materials. Effect of NaOH-treatment on dry-thermophilic anaerobic digestion of Spartina alternflora was studied by batch model under the temperature of 55 degrees C +/- 1 degrees C, at the initial total solid loading (TSL) of 20%. The results indicated that biogas production was inhibited by NaOH-treatment and improved by NaOH-treatment with water washed. The cumulative biogas yield of control (CK), NaOH-treated and NaOH-treated with water washed (NaOH + water) were 268.35 mL/g, 205.76 mL/g and 299.97 mL/g, respectively. The methane content of CK and NaOH + water treatments kept stable while fluctuation of NaOH-treated treatment during anaerobic digestion process was observed. Compared with CK and NaOH + water treatments, methane content of NaOH-treated treatment was improved by 5.30%. The content of hemi-cellulose and cellulose of S. alternifora decreased while content of lignin of S. alterniflora increased after 51-day anaerobic digestion. The crystallinity of cellulose of S. alterniflora increased after NaOH-treatment which was consistent to the result of FTIR. The lignocellulosic structure was destroyed and the biodegradability of S. alterniflora was increased by NaOH pretreatment. However, the amount of Na+ was taken into the anaerobic system, besides the high Na+ content in the plant itself which inhibited the anaerobic microorganisms. Therefore, NaOH-treatment is considered to be unsuitable for the anaerobic digestion of S. alterniflora.
Synthesis of zeolites Na-A and Na-X from tablet compressed and calcinated coal fly ash
NASA Astrophysics Data System (ADS)
Hu, Tao; Gao, Wenyan; Liu, Xin; Zhang, Yifu; Meng, Changgong
2017-10-01
Zeolites Na-A and Na-X are important synthetic zeolites widely used for separation and adsorption in industry. It is of great significance to develop energy-efficient routines that can synthesize zeolites Na-A and Na-X from low-cost raw materials. Coal fly ash (CFA) is the major residue from the combustion of coal and biomass containing more than 85% SiO2 and Al2O3, which can readily replace the conventionally used sodium silicate and aluminate for zeolite synthesis. We used Na2CO3 to replace the expensive NaOH used for the calcination of CFA and showed that tablet compression can enhance the contact with Na2CO3 for the activation of CFA through calcination for the synthesis of zeolites Na-A and Na-X under mild conditions. We optimized the control variables for zeolite synthesis and showed that phase-pure zeolite Na-A can be synthesized with CFA at reactant molar ratio, hydrothermal reaction temperature and reaction time of 1.3Na2O: 0.6Al2O3: 1SiO2: 38H2O at 80°C for 6 h, respectively, while phase-pure zeolite Na-X can be synthesized at 2.2Na2O: 0.2Al2O3: 1SiO2: 88H2O at 100°C for 8 h, respectively. The composition, morphology, specific surface area, vibration spectrum and thermogravimetry of synthesized Na-A and Na-X were further characterized.
2013-01-01
Introduction In mammals, internal Na+ homeostasis is maintained through Na+ reabsorption via a variety of Na+ transport proteins with mutually compensating functions, which are expressed in different segments of the nephrons. In zebrafish, Na+ homeostasis is achieved mainly through the skin/gill ionocytes, namely Na+/H+ exchanger (NHE3b)-expressing H+-ATPase rich (HR) cells and Na+-Cl- cotransporter (NCC)-expressing NCC cells, which are functionally homologous to mammalian proximal and distal convoluted tubular cells, respectively. The present study aimed to investigate whether or not the functions of HR and NCC ionocytes are differentially regulated to compensate for disruptions of internal Na+ homeostasis and if the cell differentiation of the ionocytes is involved in this regulation pathway. Results Translational knockdown of ncc caused an increase in HR cell number and a resulting augmentation of Na+ uptake in zebrafish larvae, while NHE3b loss-of-function caused an increase in NCC cell number with a concomitant recovery of Na+ absorption. Environmental acid stress suppressed nhe3b expression in HR cells and decreased Na+ content, which was followed by up-regulation of NCC cells accompanied by recovery of Na+ content. Moreover, knockdown of ncc resulted in a significant decrease of Na+ content in acid-acclimated zebrafish. Conclusions These results provide evidence that HR and NCC cells exhibit functional redundancy in Na+ absorption, similar to the regulatory mechanisms in mammalian kidney, and suggest this functional redundancy is a critical strategy used by zebrafish to survive in a harsh environment that disturbs body fluid Na+ homeostasis. PMID:23924428
DOE Office of Scientific and Technical Information (OSTI.GOV)
Duan, Yuhua
2014-01-01
ABSTRACT: Sodium metatitanate (Na2TiO3) was successfully synthesized via a solid-state reaction. The Na2TiO3 structure and microstructure were characterized using X-ray diffraction, scanning and transmission electron microscopy, and N2 adsorption. Then, the CO2 chemisorption mechanism on Na2TiO3 was systematically analyzed to determine the influence of temperature. The CO2 chemisorption capacity of Na2TiO3 was evaluated both dynamically and isothermally, and the products were reanalyzed to elucidate the Na2TiO3-CO2 reaction mechanism. Different chemical species (Na2CO3, Na2O, and Na4Ti5O12 or Na16Ti10O28) were identified during the CO2 capture process in Na2TiO3. In addition, some CO2 chemisorption kinetic parameters were determined. The ΔH‡ was found tomore » be 140.9 kJ/mol, to the Na2TiO3-CO2 system, between 600 and 780 °C. Results evidenced that CO2 chemisorption on Na2TiO3 highly depends on the reaction temperature. Furthermore, the experiments were theoretically supported by different thermodynamic calculations. The calculated thermodynamic properties of CO2 capture reactions by (Na2TiO3, Na4Ti5O12, and Na16Ti10O28) sodium titanates were fully investigated.« less
Kong, Xiangqiang; Luo, Zhen; Dong, Hezhong; Eneji, A. Egrinya
2012-01-01
A new split-root system was established through grafting to study cotton response to non-uniform salinity. Each root half was treated with either uniform (100/100 mM) or non-uniform NaCl concentrations (0/200 and 50/150 mM). In contrast to uniform control, non-uniform salinity treatment improved plant growth and water use, with more water absorbed from the non- and low salinity side. Non-uniform treatments decreased Na+ concentrations in leaves. The [Na+] in the ‘0’ side roots of the 0/200 treatment was significantly higher than that in either side of the 0/0 control, but greatly decreased when the ‘0’ side phloem was girdled, suggesting that the increased [Na+] in the ‘0’ side roots was possibly due to transportation of foliar Na+ to roots through phloem. Plants under non-uniform salinity extruded more Na+ from the root than those under uniform salinity. Root Na+ efflux in the low salinity side was greatly enhanced by the higher salinity side. NaCl-induced Na+ efflux and H+ influx were inhibited by amiloride and sodium orthovanadate, suggesting that root Na+ extrusion was probably due to active Na+/H+ antiport across the plasma membrane. Improved plant growth under non-uniform salinity was thus attributed to increased water use, reduced leaf Na+ concentration, transport of excessive foliar Na+ to the low salinity side, and enhanced Na+ efflux from the low salinity root. PMID:22200663
NASA Technical Reports Server (NTRS)
Kohl, F. J.; Stearns, C. A.
1979-01-01
Sodium chloride is believed to be the primary source of turbine engine contamination that contributes to hot corrosion. The behavior of NaCl-containing aerosols ingested with turbine intake air is very complex; some of the NaCl may vaporize during combustion while some may remain as particulates. The NaCl can lead to Na2SO4 formation by several possible routes or it can contribute to corrosion directly. Hydrogen or oxygen atom reaction with NaCl(c) was shown to result in the release of Na(g). Gaseous NaCl in flames can be partially converted to gaseous Na2SO4 by homogeneous reactions. The remaining gaseous NaCl and other Na-containing molecules can act as sodium carriers for condensate deposition of Na2SO4 on cool surfaces. A frozen boundary layer theory was developed to predict the rates of deposition. The condensed phase NaCl can be converted directly to condensed Na2SO4 by reaction with sulfur oxides and O2. Reaction of gaseous NaCl with Cr2O3 results in the vapor phase transport of chromium by the formation of complex Cr-containing gaseous molecules. Similar gaseous complexes are formed with molybdenum. The presence of gaseous NaCl was shown to affect the oxidation kinetics of Ni-Cr alloys. It also causes changes in the surface morphology of Al2O3 scales formed on Al-containing alloys.
Hydrogen production by sodium borohydride in NaOH aqueous solution
NASA Astrophysics Data System (ADS)
Wang, Q.; Zhang, L. F.; Zhao, Z. G.
2018-01-01
The kinetics of hydrolysis reaction of NaBH4 in NaOH aqueous solution is studied. The influence of pH of the NaOH aqueous solution on the rate of hydrogen production and the hydrogen production efficiency are studied for the hydrolysis reaction of NaBH4. The results show that the activation energy of hydrolysis reaction of NaBH4 increased with the increase of the initial pH of NaOH aqueous solution.With the increasing of the initial pH of NaOH aqueous solution, the rate of hydrogen production and hydrogen production efficiency of NaBH4 hydrolysis decrease.
Estimating Climate Resilience for Conservation across Geophysical Settings
ANDERSON, MARK G; CLARK, MELISSA; SHELDON, ARLENE OLIVERO
2014-01-01
Conservationists need methods to conserve biological diversity while allowing species and communities to rearrange in response to a changing climate. We developed and tested such a method for northeastern North America that we based on physical features associated with ecological diversity and site resilience to climate change. We comprehensively mapped 30 distinct geophysical settings based on geology and elevation. Within each geophysical setting, we identified sites that were both connected by natural cover and that had relatively more microclimates indicated by diverse topography and elevation gradients. We did this by scoring every 405 ha hexagon in the region for these two characteristics and selecting those that scored >SD 0.5 above the mean combined score for each setting. We hypothesized that these high-scoring sites had the greatest resilience to climate change, and we compared them with sites selected by The Nature Conservancy for their high-quality rare species populations and natural community occurrences. High-scoring sites captured significantly more of the biodiversity sites than expected by chance (p < 0.0001): 75% of the 414 target species, 49% of the 4592 target species locations, and 53% of the 2170 target community locations. Calcareous bedrock, coarse sand, and fine silt settings scored markedly lower for estimated resilience and had low levels of permanent land protection (average 7%). Because our method identifies—for every geophysical setting—sites that are the most likely to retain species and functions longer under a changing climate, it reveals natural strongholds for future conservation that would also capture substantial existing biodiversity and correct the bias in current secured lands. Identificación de Sitios Duraderos para la Conservación Usando la Diversidad del Paisaje y las Conexiones Locales para Estimar la Capacidad de Recuperación al Cambio Climático Resumen Los conservacionistas necesitan un método mediante el cual poder conservar la diversidad biológica mientras permiten que las especies y las comunidades se reorganicen con respecto al clima cambiante. Desarrollamos y probamos tal método, el cual basamos en características físicas asociadas con la diversidad ecológica y la capacidad de recuperación del sitio con respecto al cambio climático, en el noreste de Norteamérica. Mapeamos comprensivamente 30 escenarios geofísicos distintos basados en la geología y la elevación. Dentro de cada escenario geofísico identificamos sitios que estaban conectados por una cubierta natural y que tenían relativamente más microclimas indicados por la topografía diversa y los gradientes de elevación. Hicimos esto al puntuar cada hexágono de 450 ha en la región con estas dos características y al seleccionar aquellos que tuvieron una puntuación >SD 0.5 por encima del puntaje combinado promedio para cada escenario. Nuestra hipótesis fue que estos sitios con altas puntuaciones tuvieron la mayor capacidad de recuperación. Los comparamos con los sitios seleccionados por The Nature Conservancy por sus poblaciones de alta calidad de especies raras y sus ocurrencias de comunidades naturales. Los sitios con altos puntajes capturaron significativamente más de los sitios de biodiversidad de lo que se esperaba por casualidad (p < 0.0001): 75% de las 414 especies objetivo, 49% de las 4592 localidades de especies objetivo y 53% de las 2710 localidades de comunidades objetivo. Los escenarios de lecho rocoso calcáreo, arena gruesa y limo fino tuvieron puntos marcadamente más bajos para la capacidad de recuperación estimada y tuvieron niveles bajos de protección permanente de suelo (en promedio 7%). Ya que nuestro método identifica – para cada escenario geofísico – sitios que tienen mayor probabilidad de retener especies y funciones más tiempo bajo un clima cambiante, revela baluartes naturales para la conservación futura que también capturaría biodiversidad existente sustancial y corregiría el sesgo en tierras que actualmente están aseguradas. PMID:24673543
1991-01-01
The properties of Na-Ca-K exchange current through the plasma membrane of intact rod outer segments (ROS) isolated from bovine retinas were studied with the optical probe neutral red. Small cellular organelles such as bovine ROS do not offer an adequate collecting area to measure Na-Ca-K exchange currents with electrophysiological techniques. This study demonstrates that Na-Ca-K exchange current in bovine ROS can be measured with the dye neutral red and dual-wavelength spectrophotometry. The binding of neutral red is sensitive to transport of cations across the plasma membrane of ROS by the effect of the translocated cations on the surface potential of the intracellular disk membranes (1985. J. Membr. Biol. 88: 249-262). Electrogenic Na+ fluxes through the ROS plasma membrane were measured with a resolution of 10(5) Na+ ions/ROS per s, equivalent to a current of approximately 0.01 pA; maximal electrogenic Na-Ca-K exchange flux in bovine ROS was equivalent to a maximal exchange current of 1-2 pA. Electrogenic Na+ fluxes were identified as Na-Ca-K exchange current based on a comparison between electrogenic Na+ flux and Na(+)-stimulated Ca2+ release with respect to flux rate, Na+ dependence, and ion selectivity. Neutral red monitored the net entry of a single positive charge carried by Na+ for each Ca2+ ion released (i.e., monitored the Na-Ca-K exchange current). Na-Ca-K exchange in the plasma membrane of bovine ROS had the following properties: (a) Inward Na-Ca-K exchange current required internal Ca2+ (half-maximal stimulation at a free Ca2+ concentration of 0.9 microM), whereas outward Na-Ca-K exchange current required both external Ca2+ (half-maximal stimulation at a free Ca2+ concentration of 1.1 microM) and external K+. (b) Inward Na-Ca-K exchange current depended in a sigmoidal manner on the external Na+ concentration, identical to Na(+)-stimulated Ca2+ release measured with Ca(2+)- indicating dyes. (c) The neutral red method was modified to measure Ca(2+)-activated K+ fluxes (half-maximal stimulation at 2.7 microM free Ca2+) via the Na-Ca-K exchanger in support of the notion that the rod Na-Ca exchanger is in effect a Na-Ca-K exchanger. (d) Competitive interactions between Ca2+ and Na+ ions on the exchanger protein are described. PMID:1722239
Sodium shortage as a constraint on the carbon cycle in an inland tropical rainforest.
Kaspari, Michael; Yanoviak, Stephen P; Dudley, Robert; Yuan, May; Clay, Natalie A
2009-11-17
Sodium (Na) is uncommon in plants but essential to the metabolism of plant consumers, both decomposers and herbivores. One consequence, previously unexplored, is that as Na supplies decrease (e.g., from coastal to inland forests), ecosystem carbon should accumulate as detritus. Here, we show that adding NaCl solution to the leaf litter of an inland Amazon forest enhanced mass loss by 41%, decreased lignin concentrations by 7%, and enhanced decomposition of pure cellulose by up to 50%, compared with stream water alone. These effects emerged after 13-18 days. Termites, a common decomposer, increased 7-fold on +NaCl plots, suggesting an agent for the litter loss. Ants, a common predator, increased 2-fold, suggesting that NaCl effects cascade upward through the food web. Sodium, not chloride, was likely the driver of these patterns for two reasons: two compounds of Na (NaCl and NaPO(4)) resulted in equivalent cellulose loss, and ants in choice experiments underused Cl (as KCl, MgCl(2), and CaCl(2)) relative to NaCl and three other Na compounds (NaNO(3), Na(3)PO(4), and Na(2)SO(4)). We provide experimental evidence that Na shortage slows the carbon cycle. Because 80% of global landmass lies >100 km inland, carbon stocks and consumer activity may frequently be regulated via Na limitation.
Sodium shortage as a constraint on the carbon cycle in an inland tropical rainforest
Kaspari, Michael; Yanoviak, Stephen P.; Dudley, Robert; Yuan, May; Clay, Natalie A.
2009-01-01
Sodium (Na) is uncommon in plants but essential to the metabolism of plant consumers, both decomposers and herbivores. One consequence, previously unexplored, is that as Na supplies decrease (e.g., from coastal to inland forests), ecosystem carbon should accumulate as detritus. Here, we show that adding NaCl solution to the leaf litter of an inland Amazon forest enhanced mass loss by 41%, decreased lignin concentrations by 7%, and enhanced decomposition of pure cellulose by up to 50%, compared with stream water alone. These effects emerged after 13–18 days. Termites, a common decomposer, increased 7-fold on +NaCl plots, suggesting an agent for the litter loss. Ants, a common predator, increased 2-fold, suggesting that NaCl effects cascade upward through the food web. Sodium, not chloride, was likely the driver of these patterns for two reasons: two compounds of Na (NaCl and NaPO4) resulted in equivalent cellulose loss, and ants in choice experiments underused Cl (as KCl, MgCl2, and CaCl2) relative to NaCl and three other Na compounds (NaNO3, Na3PO4, and Na2SO4). We provide experimental evidence that Na shortage slows the carbon cycle. Because 80% of global landmass lies >100 km inland, carbon stocks and consumer activity may frequently be regulated via Na limitation. PMID:19884505
The H,K-ATPase beta-subunit can act as a surrogate for the beta-subunit of Na,K-pumps.
Horisberger, J D; Jaunin, P; Reuben, M A; Lasater, L S; Chow, D C; Forte, J G; Sachs, G; Rossier, B C; Geering, K
1991-10-15
Na,K-ATPase and H,K-ATPase are the only members of the P-type ATPases in which a glycosylated beta-subunit is part of the purified active enzyme. In this study, we have followed the synthesis and the posttranslational processing of the beta-subunit of H,K-ATPase (beta HK) in Xenopus oocytes injected with beta HK cRNA and have tested whether it can act as a surrogate for the beta-subunit of Na,K-ATPase (beta NaK) to support the functional expression of Na,K-pumps. In Xenopus oocytes, beta HK is processed from an Endo H-sensitive 51-kDa coreglycosylated form to an Endo H-resistant 71-kDa fully glycosylated form. Similar to beta NaK, beta HK can stabilize and increase the trypsin resistance of alpha-subunits of Na,K-ATPase (alpha NaK). Finally, expression of beta HK together with alpha NaK leads to an increased number of ouabain binding sites at the plasma membrane accompanied by an increased Rb+ uptake and Na,K-pump current. Our data suggest that beta HK, similar to beta NaK, can assemble to alpha NaK, support the structural maturation and the intracellular transport of catalytic alpha NaK, and ultimately form active alpha NaK-beta HK complexes with Na,K-pump transport properties.
Effect of NaNO3 concentration on anodic electrochemical behavior on the Sb surface in NaOH solution
NASA Astrophysics Data System (ADS)
He, Yun-long; Xu, Rui-dong; He, Shi-wei; Chen, Han-sen; Li, Kuo; Zhu, Yun; Shen, Qing-feng
2018-03-01
The effect of NaNO3 concentration on the anodic electrochemical behavior of antimony in 4 M NaOH solution was investigated using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) analyses. The mechanism of NO 3 - concentration effect on the anodic electrochemical behavior of antimony was proposed, and its availability was confirmed by experimental results. The effect of NaNO3 on the anodic behavior of antimony in NaOH solution can be interpreted as a stepwise formation of different antimony compounds with different NaNO3 concentrations. Metallic antimony is apt to be oxidized into Sb2O3 within the NaNO3 concentration range of 0-0.48 M. NaSbO3 can be found on the antimony surface when the NaNO3 concentration increases gradually. Insoluable NaSbO3 inhibits the anodic oxidation of antimony due to its shielding effect on the mass transport of the reactants and products. Surface morphology and composition were analyzed by X-ray photoelectron spectroscopy (XPS), scanning electronic microscopy (SEM), and electron dispersion spectroscopy (EDS) analyses. Results indicate that the anodic oxidation layer is composed of Sb2O3, NaSbO3, and Sb. The atomic proportion of antimony in the form of NaSbO3 increases with increasing NaNO3 concentration due to the powerful oxidizing property of NaNO3.
Hydrogen-fluorine exchange in NaBH4-NaBF4.
Rude, L H; Filsø, U; D'Anna, V; Spyratou, A; Richter, B; Hino, S; Zavorotynska, O; Baricco, M; Sørby, M H; Hauback, B C; Hagemann, H; Besenbacher, F; Skibsted, J; Jensen, T R
2013-11-07
Hydrogen-fluorine exchange in the NaBH4-NaBF4 system is investigated using a range of experimental methods combined with DFT calculations and a possible mechanism for the reactions is proposed. Fluorine substitution is observed using in situ synchrotron radiation powder X-ray diffraction (SR-PXD) as a new Rock salt type compound with idealized composition NaBF2H2 in the temperature range T = 200 to 215 °C. Combined use of solid-state (19)F MAS NMR, FT-IR and DFT calculations supports the formation of a BF2H2(-) complex ion, reproducing the observation of a (19)F chemical shift at -144.2 ppm, which is different from that of NaBF4 at -159.2 ppm, along with the new absorption bands observed in the IR spectra. After further heating, the fluorine substituted compound becomes X-ray amorphous and decomposes to NaF at ~310 °C. This work shows that fluorine-substituted borohydrides tend to decompose to more stable compounds, e.g. NaF and BF3 or amorphous products such as closo-boranes, e.g. Na2B12H12. The NaBH4-NaBF4 composite decomposes at lower temperatures (300 °C) compared to NaBH4 (476 °C), as observed by thermogravimetric analysis. NaBH4-NaBF4 (1:0.5) preserves 30% of the hydrogen storage capacity after three hydrogen release and uptake cycles compared to 8% for NaBH4 as measured using Sievert's method under identical conditions, but more than 50% using prolonged hydrogen absorption time. The reversible hydrogen storage capacity tends to decrease possibly due to the formation of NaF and Na2B12H12. On the other hand, the additive sodium fluoride appears to facilitate hydrogen uptake, prevent foaming, phase segregation and loss of material from the sample container for samples of NaBH4-NaF.
1982-01-01
Na+- and CA2+-sensitive microelectrodes were used to measure intracellular Na+ and Ca2+ activities (alpha iCa) of sheep ventricular muscle and Purkinje strands to study the interrelationship between Na+ and Ca2+ electrochemical gradients (delta muNa and delta muCa) under various conditions. In ventricular muscle, alpha iNa was 6.4 +/- 1.2 mM and alpha iCa was 87 +/- 20 nM ([Ca/+] = 272 nM). A graded decrease of external Na+ activity (alpha oNa) resulted in decrease of alpha iNa, and increase of alpha iCa. There was increase of twitch tension in low- alpha oNa solutions, and occasional increase of resting tension in 40% alpha oNa. Increase of external Ca2+ (alpha oCa) resulted in increase of alpha iCa and decrease of alpha iNa. Decrease of alpha oCa resulted in decrease of alpha iCa and increase of alpha iNa. The apparent resting Na-Ca energy ratio (delta muCa/delta muNa) was between 2.43 and 2.63. When the membrane potential (Vm) was depolarized by 50 mM K+ in ventricular muscle, Vm depolarized by 50 mV, alpha iNa decreased, and alpha iCa increased, with the development of a contracture. The apparent energy coupling ratio did not change with depolarization. 5 x 10(-6) M ouabain induced a large increase in alpha iNa ad alpha iCa, accompanied by an increase in twitch and resting tension. Under the conditions we have studied, delta muNa and delta muCa appeared to be coupled and n was nearly constant at 2.5, as would be expected if the Na-Ca exchange system was able to set the steady level of alpha iCa. Tension threshold was about 230 nM alpha iCa. The magnitude of twitch tension was directly related to alpha iCa. PMID:6292328
Yılmaz, Zehra Vural; Akkaş, Elif; Türkmen, Gülenay Gençosmanoğlu; Kara, Özgür; Yücel, Aykan; Uygur, Dilek
2017-02-01
In this study, we hypothesized that dietary salt and potassium intake may be related with blood pressure, kidney damage and perinatal outcome in pregnants with preeclampsia (PE). In total, 200 women (50 control women with healthy pregnancy, 150 women with PE) were recruited for the study. Daily salt and potassium intake was estimated based on calculation of 24-hour urinary sodium U[Na+] and potassium U[K+] excretion. U[Na+]/[K+] was calculated by dividing U[Na+] by U[K+]. At the end of the measurements, the pregnant women with PE (n=150) were divided into tertiles according to U[Na+]/[K+]: low Na/K group (n=50, mean U[Na+]/[K+]: 1,04±0,32), medium Na/K group (n=50, mean U[Na+]/[K+]: 2,49± 0,54), high Na/K group (n=50, mean U[Na+]/[K+]: 6,62±3,41). The mean SBP and DBP levels were significantly lower in low Na/K group compared with medium or high Na/K groups (p=0.024, p=0.0002; respectively). Serum creatinine was significantly lower in low Na/K group than high Na/K group (p=0.025). Frequency of severe preeclampsia is lower in low Na/K group than medium or high Na/K groups (p=0.002, p=0.0001; respectively). Birth weight and gestational age at birth were higher in low Na/K group compared with high Na/K group (p=0.045, p=0.0002; respectively). After adjusting for covariates, SBP and DBP and creatinine levels were independently associated with 24 hours urinary [Na+]/[K+] Conclusion: These findings suggest that pregnant with PE with high dietary salt and low potassium intake may have greater maternal and neonatal morbidity risk than pregnant with PE under low dietary salt and high potassium intake.
2012-03-23
Carrier-based fighters 0 0 0 0 0 ~60 ~90 Helicopters n/a n/a n/a n/a ~34 ~153 ~157 Subtotal above aircraft n/a n/a n/a n/a ~179 ~468 ~ 505 Source...strategic emphasis on the Asia-Pacific region and the Middle East, but are applicable anywhere on the globe where U.S. national security or vital...support application against ground forces. Developing a near-term, long-range naval gunfire engagement capability for air, missile, and surface
1995-03-15
10 200 1-Chloro-2,3-epoxypropene NA Acetonitrile NA Ethylene oxide NA Methyl methacrylate NA NA = Information not available. A library search can be...05-4 Vinyl Chloride C2H3CL 75-01-4 Xylene, total TXYLEN - 1-Chloro-2,3-epoxypropene Acetonitrile CH3CN Ethylene oxide ETOX Methyl methacrylate PLEXI...0.010 10 200 Vinyl Chloride 0.010 10 200 Xylene, total 0.010 10 200 1-Chloro-2,3-epoxypropene NA Acetonitrile NA Ethylene oxide NA Methyl methacrylate
A cluster ion chemistry for the mesospheric sodium layer
NASA Technical Reports Server (NTRS)
Richter, E. S.; Sechrist, C. F., Jr.
1979-01-01
A cluster ion chemistry for sodium is developed which relates the Na(+) profile to the Na profile using reactions involving Na(+).N2, Na(+).CO2, and Na(+).H2O. Removal of sodium from the mesosphere is accomplished by the formation of higher order clusters of the form Na(+).(H2O)n which presumably precipitate to the lower atmosphere. This sink is most effective in the 80-85 km altitude range. The chemical equilibrium model is applied to experimental observations of the Na and Na(+) layers.
Asano, Y
1978-01-01
Thyroid hormone (T3) increased Na+ dependent respiration accompanied by an increase in NaK-ATPase activity. Administration of T3 increased intracellular K+ concentration and Na/K ratio in thyroidectomized rats, and the Na+ efflux rate constant incubated in oxygenized Na+, K+-Ringers in euthyroid rats. However, the magnitude of the changes in intracellular K+ concentration was modest or invisible in comparison to the changes in QO2(t) and NaK-ATPase activity. The Na+ and K+ efflux rate constants in K+-free +ouabain Ringers were increased by T3 in both thyroidectomized and euthyroid rats. Thus, thyroid hormone stimulates not only Na pump but also the permeability of cell membrane to Na+ and K+. The both effects might contribute to the thyroid thermogenesis.
Ultrasound-assisted synthesis and processing of carbon materials
NASA Astrophysics Data System (ADS)
Fortunato, Maria E.
2011-12-01
Part I: Porous carbons are of interest in many applications because of their high surface areas and other physicochemical properties, and much effort has been directed towards developing new methods for controlling the porosity of carbons. Ultrasonic spray pyrolysis (USP) is an aerosol method suitable for large-scale, continuous synthesis of materials. Ultrasound is used to create aerosol droplets of a precursor solution which serve as micron-sized spherical reactors for materials synthesis. This work presents a precursor system for the template-free USP synthesis of porous carbons using low-cost precursors that do not evolve or require hazardous chemicals: sucrose was used as the carbon source, and sodium carbonate, sodium bicarbonate, or sodium nitrate was added as a decomposition catalyst and porogen. The USP carbons had macroporous interiors and microporous shells with surface areas as high as 800 m2/g and a narrow pore size distribution. It was determined that the interior porosity was a result of the gas evolution from salt decomposition and not from the presence of a salt template. Porous carbon is frequently used as a catalyst support because it provides high surface area and it is chemically and physically stable under many anoxic reaction conditions. Typically, the preparation of supported catalysts requires multiple steps for carbonization and metal impregnation. In this work, iron-impregnated porous carbon microspheres (Fe-C) were prepared by a one-step USP process by incorporating both the carbon and metal sources into the precursor solution. Carbonization, pore formation, metal impregnation, and metal activation occurred simultaneously to produce Fe-C materials with surface areas as high as 800 m2/g and up to 10 wt% Fe incorporated as nanoparticles < 20 nm in diameter. Fe-C was used as a catalyst to reduce aqueous hexavalent chromium, which demonstrated the accessibility of the iron nanoparticles despite the fact that they are likely encapsulated in the porous carbon support. Part II: The effects of high intensity ultrasound arise from acoustic cavitation: the formation, growth, and collapse of bubbles in a liquid. Bubble collapse produces intense localized heating (˜5000 K), high pressures (˜300 atm), and enormous heating and cooling rates (>109 K/sec). In solid-liquid slurries, surface erosion and particle fracture occur due to the shockwaves and microjets formed from asymmetric bubble collapse at extended surfaces. The chemical and physical effects of ultrasound have been studied as an adjunct to the traditional chemical pretreatment of lignocellulosic biomass for ethanol production. Lignocellulosic biomass consists of cellulose, hemicellulose, and lignin. The surface effects of ultrasound were used in this work to increase the accessibility of the cellulose, which can be converted to glucose and then fermented into ethanol. The lignocellulosic biomass used in this work was Miscanthus x giganteus (Mxg) which was grown at the University of Illinois at Urbana-Champaign. The chemical effects of NaOH pretreatment on Mxg were enhanced by ultrasound: greater delignification and a significant increase in the amount of pores >5 nm were observed. ˜ 70% of the theoretical glucose yield was obtained by enzymatic saccharification of the ultrasound-assisted NaOH-pretreated Mxg; this is comparable to the yields that can be obtained by traditional alkaline pretreatments, but it was achieved in a shorter time and at a lower temperature. Because the apparatus used for laboratory studies is not a likely device for scale-up, the economics of ultrasound with regards to energy balance are not yet resolved.
Wehner, Frank; Tinel, Hanna
1998-01-01
In rat hepatocytes under hypertonic stress, the entry of Na+ (which is thereafter exchanged for K+ via Na+-K+-ATPase) plays the key role in regulatory volume increase (RVI).In the present study, the contributions of Na+ conductance, Na+-H+ exchange and Na+-K+-2Cl− symport to this process were quantified in confluent primary cultures by means of intracellular microelectrodes and cable analysis, microfluorometric determinations of cell pH and buffer capacity, and measurements of frusemide (furosemide)/bumetanide-sensitive 86Rb+ uptake, respectively. Osmolarity was increased from 300 to 400 mosmol l−1 by addition of sucrose.The experiments indicate a relative contribution of approximately 4:1:1 to hypertonicity-induced Na+ entry for the above-mentioned transporters and the overall Na+ yield equalled 51 mmol l−1 (10 min)−1.This Na+ gain is in good agreement with the stimulation of Na+ extrusion via Na+-K+-ATPase plus the actual increase in cell Na+, namely 55 mmol l−1 (10 min)−1, as was determined on the basis of ouabain-sensitive 86Rb+ uptake and by means of Na+-sensitive microelectrodes, respectively.The overall increase in Na+ and K+ activity plus the expected concomitant increase in cell Cl− equalled 68 mmol l−1, which fits well with the increase in osmotic activity expected to occur from an initial cell shrinkage to 87.5 % and a RVI to 92.6 % of control, namely 53 mosmol l−1.The prominent role of Na+ conductance in the RVI of rat hepatocytes could be confirmed on the basis of the pharmacological profile of this process, which was characterized by means of confocal laser-scanning microscopy. PMID:9481677
1985-01-01
Noise analysis of the Na+ channels of the apical membranes of frog skin bathed symmetrically in a Cl-HCO3 Ringer solution was done with amiloride and CGS 4270. Tissues were studied in their control states and after inhibition of transepithelial Na+ transport (Isc) by addition of quinine or quinidine to the apical solution. A critical examination of the amiloride-induced noise indicated that the single channel Na+ currents (iNa) were decreased by quinine and quinidine, probably because of depolarization of apical membrane voltage. Despite considerable statistical uncertainty in the methods of estimation of the Na+ channel density with amiloride-induced noise (NA, see text), the striking observation was a large increase of NA with amiloride inhibition of the rate of Na+ entry into the cells. NA was increased to 406% of control, whereas Isc was inhibited to 8.6% of control by 6 microM amiloride. Studies were done also with the Na+ channel blocker CGS 4270. Noise analysis with this compound was advantageous, permitting iCGSNa and NCGS to be measured in individual tissues with a relatively small inhibition of Isc. As with amiloride, inhibition of Isc with CGS 4270 caused large increases of the Na+ channel density (approximately 200% at approximately 35% inhibition of the Isc). Quinine and quinidine caused an approximately 50% increase of Na+ channel density while inhibiting iNa by approximately 60-70%. As inhibition of Na+ entry leads to an increase of Na+ channel density, a mechanism of autoregulation appears to be a major factor in adjusting the apical membrane Na+ permeability of the cells. PMID:2409219
Differences in the sodium content of bread products in the USA and UK: implications for policy.
Coyne, Kasey J; Baldridge, Abigail S; Huffman, Mark D; Jenner, Katharine; Xavier, Dagan; Dunford, Elizabeth K
2018-02-01
Americans consume Na in excess of daily recommendations. Most dietary Na comes from packaged foods, and bread is a major contributor. In the UK, national Na reduction strategies contributed to lower Na levels in packaged foods and lower population Na intake. Similar initiatives are emerging in the USA and require surveillance to assess effectiveness. We aimed to examine Na levels in bread products in the USA and compare levels with similar UK products. Na data for bread products were obtained from the US Label Insight Open Data Initiative (n 4466) and the FoodSwitch UK database (n 1651). Mean, median and range of Na content, and proportion of products meeting Na targets established by the National Salt Reduction Initiative (NSRI) and the UK Department of Health (DH) were calculated overall, by bread type and by country. Mean (sd) Na content in bread was 455 (170) mg/100 g in the USA and 406 (179) mg/100 g in the UK. In both countries, savoury bread had the highest mean Na (USA=584 mg/100 g, UK=543 mg/100 g) and fruit bread the lowest mean Na (USA=345 mg/100 g, UK=277 mg/100 g). Na content of US bread products was 12 % higher than in the UK, with 21 % of US bread products and 31 % of UK bread products meeting the NSRI and DH targets, respectively. US bread products have, on average, 12 % more Na than similar products in the UK. Variation in Na content within product categories, and between countries, suggests the feasibility of manufacturing products with lower Na to lower dietary Na intake.
Three homologous subunits form a high affinity peptide-gated ion channel in Hydra.
Dürrnagel, Stefan; Kuhn, Anne; Tsiairis, Charisios D; Williamson, Michael; Kalbacher, Hubert; Grimmelikhuijzen, Cornelis J P; Holstein, Thomas W; Gründer, Stefan
2010-04-16
Recently, three ion channel subunits of the degenerin (DEG)/epithelial Na(+) channel (ENaC) gene family have been cloned from the freshwater polyp Hydra magnipapillata, the Hydra Na(+) channels (HyNaCs) 2-4. Two of them, HyNaC2 and HyNaC3, co-assemble to form an ion channel that is gated by the neuropeptides Hydra-RFamides I and II. The HyNaC2/3 channel is so far the only cloned ionotropic receptor from cnidarians and, together with the related ionotropic receptor FMRFamide-activated Na(+) channel (FaNaC) from snails, the only known peptide-gated ionotropic receptor. The HyNaC2/3 channel has pore properties, like a low Na(+) selectivity and a low amiloride affinity, that are different from other channels of the DEG/ENaC gene family, suggesting that a component of the native Hydra channel might still be lacking. Here, we report the cloning of a new ion channel subunit from Hydra, HyNaC5. The new subunit is closely related to HyNaC2 and -3 and co-localizes with HyNaC2 and -3 to the base of the tentacles. Coexpression in Xenopus oocytes of HyNaC5 with HyNaC2 and -3 largely increases current amplitude after peptide stimulation and affinity of the channel to Hydra-RFamides I and II. Moreover, the HyNaC2/3/5 channel has altered pore properties and amiloride affinity, more similarly to other DEG/ENaC channels. Collectively, our results suggest that the three homologous subunits HyNaC2, -3, and -5 form a peptide-gated ion channel in Hydra that could contribute to fast synaptic transmission.
Quantification of Na+,K+ pumps and their transport rate in skeletal muscle: Functional significance
2013-01-01
During excitation, muscle cells gain Na+ and lose K+, leading to a rise in extracellular K+ ([K+]o), depolarization, and loss of excitability. Recent studies support the idea that these events are important causes of muscle fatigue and that full use of the Na+,K+-ATPase (also known as the Na+,K+ pump) is often essential for adequate clearance of extracellular K+. As a result of their electrogenic action, Na+,K+ pumps also help reverse depolarization arising during excitation, hyperkalemia, and anoxia, or from cell damage resulting from exercise, rhabdomyolysis, or muscle diseases. The ability to evaluate Na+,K+-pump function and the capacity of the Na+,K+ pumps to fill these needs require quantification of the total content of Na+,K+ pumps in skeletal muscle. Inhibition of Na+,K+-pump activity, or a decrease in their content, reduces muscle contractility. Conversely, stimulation of the Na+,K+-pump transport rate or increasing the content of Na+,K+ pumps enhances muscle excitability and contractility. Measurements of [3H]ouabain binding to skeletal muscle in vivo or in vitro have enabled the reproducible quantification of the total content of Na+,K+ pumps in molar units in various animal species, and in both healthy people and individuals with various diseases. In contrast, measurements of 3-O-methylfluorescein phosphatase activity associated with the Na+,K+-ATPase may show inconsistent results. Measurements of Na+ and K+ fluxes in intact isolated muscles show that, after Na+ loading or intense excitation, all the Na+,K+ pumps are functional, allowing calculation of the maximum Na+,K+-pumping capacity, expressed in molar units/g muscle/min. The activity and content of Na+,K+ pumps are regulated by exercise, inactivity, K+ deficiency, fasting, age, and several hormones and pharmaceuticals. Studies on the α-subunit isoforms of the Na+,K+-ATPase have detected a relative increase in their number in response to exercise and the glucocorticoid dexamethasone but have not involved their quantification in molar units. Determination of ATPase activity in homogenates and plasma membranes obtained from muscle has shown ouabain-suppressible stimulatory effects of Na+ and K+. PMID:24081980
Oxidation of ethanol on NaX zeolite modified with transition metals
NASA Astrophysics Data System (ADS)
Mirzai, J. I.; Nadirov, P. A.; Velieva, A. D.; Muradkhanli, V. G.
2017-06-01
NaLaX, NaX + Co, and NaPdX catalysts are synthesized by modification of NaX zeolite with transition metals (La, Co, Pd). The activity of the prepared materials in catalytic ethanol oxidation is studied in the temperature range of 423-723 K. It is shown that NaPdX and NaX + Co accelerate the reactions of partial and complete oxidation of ethanol as the temperature rises. NaLaX accelerates both intramolecular and intermolecular dehydration of alcohol. It is shown that the NaPdX (1.0% Pd) sample has the highest activity in the complete oxidation of alcohol with the formation of CO2.
Veterans Attitude Tracking Study -- 1983, Wave I. Data Tables. Supplement 1,
1984-05-01
5.6 9.9 6.8 8.2 Admini strative 18.5 20.4 13.U 17.2 Medical 3.6 0.7 0.7 1.3 Other 0.4 0.7 0.0 0.9 Dont know .b 4.6 4.1 3.4 1) Asked only of respondents...toward Guard/ Reserve participation, -- Talked with their co-workers about enlisting in the Guard/Reserve, or -- Seen notices, posters , or other...A N/A 72.9 9 17 Total N/A N/A N/A N/A 100% (11.6%) (23.5%) Seen any notices, posters , or other literature at workplace(’Q R-35b) Yes N/A N/A N/A N/A
Åsli, Magnus; Ofstad, Ragni; Böcker, Ulrike; Jessen, Flemming; Einen, Olai; Mørkøre, Turid
2016-03-15
Negative health effects associated with excessive sodium (Na) intake have increased the demand for tasty low-Na products (<2% NaCl) rather than traditional heavily salted fish products (∼20% NaCl). This study investigates the causes of improved yield and liquid retention of fish muscle brined with a combination of salt (NaCl) and sodium bicarbonate (NaHCO3 ). Water characteristics and microstructure of saithe (Pollachius virens L.) muscle brined in solutions of NaCl and NaHCO3 or NaCl alone were compared using low-field nuclear magnetic resonance (LF-NMR) T2 relaxometry, microscopy, salt content, liquid retention and colorimetric measurements. Saithe muscle was brined for 92 h in 0, 30, 60, 120 or 240 g kg(-1) NaCl or the respective solutions with added 7.5 g kg(-1) NaHCO3 . NaHCO3 inclusion improved the yield in solutions ranging from 0 to 120 g kg(-1) NaCl, with the most pronounced effect being observed at 30 g kg(-1) NaCl. The changes in yield were reflected in water mobility, with significantly shorter T2 relaxation times in all corresponding brine concentrations. Salt-dependent microstructural changes were revealed by light microscopy, where NaHCO3 supplementation resulted in greater intracellular space at 30 and 60 g kg(-1) NaCl. Sodium bicarbonate addition to low-salt solutions can improve yield and flesh quality of fish muscle owing to altered water mobility and wider space between the muscle cells. © 2015 Society of Chemical Industry.
Iron bioavailability in corn-masa tortillas is improved by the addition of disodium EDTA.
Walter, Tomás; Pizarro, Fernando; Olivares, Manuel
2003-10-01
Corn-masa flour flat bread tortillas are the main staple of Mexican and Central American populations. Due to high concentrations of inhibitors of iron absorption, the bioavailability from this matrix is unknown. We wanted to determine the most suitable fortificant that would efficaciously improve iron bioavailability. In tortillas prepared with commercial precooked, lime-treated, corn-masa flour, we examined the in vitro solubility of the following forms of iron: native iron with and without Na2EDTA, elemental reduced iron plus Na2EDTA, ferrous fumarate with and without Na2EDTA, bisglycine iron, ferrous sulfate and NaFeEDTA. We also examined the in vivo bioavailability in humans with double radioiron erythrocyte incorporation of ferrous fumarate with and without Na2EDTA, bisglycine iron, NaFeEDTA and native iron plus Na2EDTA, beans and rice. In vitro, solubility ranged from 1% in iron forms without Na2EDTA to 19.4% for NaFeEDTA. Forms of iron with Na2EDTA had intermediate values. In vivo radioiron studies showed that iron forms without Na2EDTA also had low bioavailability (< or =1%). NaFeEDTA had the highest bioavailability (5.3%). The bioavailability of all iron forms improved significantly when tested with Na2EDTA (<0.05). Adding Na2EDTA to ferrous fumarate increased bioavailability from 0.87% to 2.9% (P < 0.001). We conclude that NaFeEDTA is the form of iron best absorbed, but alternatively, ferrous fumarate plus Na2EDTA comprises a feasible option as a fortificant.
Cation activation of the pig kidney sodium pump: transmembrane allosteric effects of sodium.
Karlish, S J; Stein, W D
1985-01-01
We have studied activation by Na or Rb ions of different transport modes of the Na-K pump, using phospholipid vesicles reconstituted with pig kidney Na-K-ATPase. The shape of the activation curves, sigmoid or quasi-hyperbolic, depends on the nature of the cation at the opposite surface and not on the specific mode of transport. ATP-dependent Na uptake into K-containing vesicles (Na-K exchange) is activated by cytoplasmic Na along a highly sigmoid curve in the absence of extracellular Na (Hill number, nH = 1.9). Activation displays progressively less-sigmoid curves as extracellular Na is raised to 150 mM (nH = 1.2). The maximal rate of the Na-K exchange is not affected. Na is not transported from the extracellular face by the pump in the presence of excess extracellular K, and the transmembrane effects of the extracellular Na are therefore 'allosteric' in nature. ATP-dependent Na-Na exchange (Lee & Blostein, 1980) and classical ATP-plus-ADP-dependent Na-Na exchange are activated by cytoplasmic Na along hyperbolic curves. ATP-dependent Na uptake into Tris-containing vesicles is activated by cytoplasmic Na along a somewhat sigmoidal curve. (ATP + Pi)-dependent Rb-Rb exchange is activated by cytoplasmic and extracellular Rb along strictly hyperbolic curves. The same applies for Rb-Rb exchange in the presence or absence of ATP or Pi alone. The presence of a high concentration of extracellular Na together with extracellular Rb induces a sigmoidal activation by cytoplasmic Rb of (ATP + Pi)-dependent Rb-Rb exchange (nH = 1.45) but does not affect the maximal rate of exchange. Slow passive Rb fluxes through the pump observed in the absence of other pump ligands (see Karlish & Stein, 1982 alpha) are activated by cytoplasmic Rb along a strictly hyperbolic curve with extracellular Rb, nH = 1.0 (Rb-Rb exchange), along a strongly sigmoid curve with extracellular Na, nH = 1.5 (Rb-Na exchange), and along less-sigmoid curves with extracellular Tris, nH = 1.24 (net Rb flux) or extracellular Li, nH = 1.2 (Rb-Li exchange). Activation of the passive Rb fluxes by extracellular Rb is hyperbolic in the presence of cytoplasmic Rb, Li or Tris but is sigmoid in the presence of cytoplasmic Na (nH = 1.36). Inhibition by cytoplasmic Na of passive Rb fluxes from the cytoplasmic to the extracellular face of the pump depends on the nature of the cation at the extracellular surface.(ABSTRACT TRUNCATED AT 400 WORDS) PMID:2582111
Hosny, E A; Al-Shora, H I; Elmazar, M M
2001-09-01
Insulin suppositories were formulated using Witepsol W35 as a base to investigate the effect of various bile salts/acids on the plasma glucose concentration of diabetic beagle dogs. Comparison of the effect of these formulations was made with that produced by insulin subcutaneous injections. Of the bile salts/acids studied, incorporation of 100 mg of deoxycholic acid (DCA), sodium cholate (NaC), or sodium deoxycholate (NaDC) with insulin (10 U/Kg) showed that suppositories containing NaDC produced the highest area under the curve (AUC) and relative hypoglycemia (RH) of 290 +/- 83 mg%h and 28% +/- 8.1%, respectively. To study the optimum amount of NaDC in insulin suppositories to produce the highest RH, 50-200 mg/suppository were used, and we found that 150 mg NaDC produced 35% +/- 13% RH. We also studied the influence of different doses of insulin (5-20 U/kg) in the presence of NaDC (100 mg). It was found that increase of the insulin dose was accompanied by an increase in AUC and maximum reduction in plasma glucose level Cmax. A combination of NaDC (100 mg) and NaC (50 mg) produced an AUC of 252 +/- 13mg%h and an RH of 49% +/- 2.6%, which were higher than produced by either of its individual components (NaC 50 mg or NaDC 100 mg) when used alone or when compared with an equivalent amount of NaDC (150 mg). When the effect of sodium taurocholate (NaTC) and sodium taurodeoxycholate (NaTDC) was studied, it was found that an insulin suppository containing 100 mg of either NaTC or NaTDC produced an RH equivalent to that produced previouslY with a mixture of NaDC (100 mg) and NaC (50 mg). On the other hand, NaC (50 mg) did not improve the hypoglycemic effect of NaTC any further. In conclusion, a relative hYpoglycemia of about 50% can be reached using insulin suppositories containing Witepsol W35 as a base and NaDC plus NaC (100 mg plus 50 mg, respectively), NaTDC (100mg), or NaTC (100 mg) as rectal absorption enhancers of insulin. A desirable hypoglycemia, expressed as Cmax, and/or AUC can be reached by adjusting the insulin dose in the formulation according to the degree of hyperglycemia.
Dietary sodium induces a redistribution of the tubular metabolic workload
Udwan, Khalil; Abed, Ahmed; Roth, Isabelle; Dizin, Eva; Maillard, Marc; Bettoni, Carla; Loffing, Johannes; Wagner, Carsten A.; Edwards, Aurélie
2017-01-01
Key points Body Na+ content is tightly controlled by regulated urinary Na+ excretion.The intrarenal mechanisms mediating adaptation to variations in dietary Na+ intake are incompletely characterized.We confirmed and expanded observations in mice that variations in dietary Na+ intake do not alter the glomerular filtration rate but alter the total and cell‐surface expression of major Na+ transporters all along the kidney tubule.Low dietary Na+ intake increased Na+ reabsorption in the proximal tubule and decreased it in more distal kidney tubule segments.High dietary Na+ intake decreased Na+ reabsorption in the proximal tubule and increased it in distal segments with lower energetic efficiency.The abundance of apical transporters and Na+ delivery are the main determinants of Na+ reabsorption along the kidney tubule.Tubular O2 consumption and the efficiency of sodium reabsorption are dependent on sodium diet. Abstract Na+ excretion by the kidney varies according to dietary Na+ intake. We undertook a systematic study of the effects of dietary salt intake on glomerular filtration rate (GFR) and tubular Na+ reabsorption. We examined the renal adaptive response in mice subjected to 7 days of a low sodium diet (LSD) containing 0.01% Na+, a normal sodium diet (NSD) containing 0.18% Na+ and a moderately high sodium diet (HSD) containing 1.25% Na+. As expected, LSD did not alter measured GFR and increased the abundance of total and cell‐surface NHE3, NKCC2, NCC, α‐ENaC and cleaved γ‐ENaC compared to NSD. Mathematical modelling predicted that tubular Na+ reabsorption increased in the proximal tubule but decreased in the distal nephron because of diminished Na+ delivery. This prediction was confirmed by the natriuretic response to diuretics targeting the thick ascending limb, the distal convoluted tubule or the collecting system. On the other hand, HSD did not alter measured GFR but decreased the abundance of the aforementioned transporters compared to NSD. Mathematical modelling predicted that tubular Na+ reabsorption decreased in the proximal tubule but increased in distal segments with lower transport efficiency with respect to O2 consumption. This prediction was confirmed by the natriuretic response to diuretics. The activity of the metabolic sensor adenosine monophosphate‐activated protein kinase (AMPK) was related to the changes in tubular Na+ reabsorption. Our data show that fractional Na+ reabsorption is distributed differently according to dietary Na+ intake and induces changes in tubular O2 consumption and sodium transport efficiency. PMID:28940314
Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels.
Zhu, Shunyi; Peigneur, Steve; Gao, Bin; Lu, Xiuxiu; Cao, Chunyang; Tytgat, Jan
2012-01-01
α-Scorpion toxins constitute a family of peptide modulators that induce a prolongation of the action potential of excitable cells by inhibiting voltage-gated sodium channel inactivation. Although they all adopt a conserved structural scaffold, the potency and phylogentic preference of these toxins largely vary, which render them an intriguing model for studying evolutionary diversification among family members. Here, we report molecular characterization of a new multigene family of α-toxins comprising 13 members (named MeuNaTxα-1 to MeuNaTxα-13) from the scorpion Mesobuthus eupeus. Of them, five native toxins (MeuNaTxα-1 to -5) were purified to homogeneity from the venom and the solution structure of MeuNaTxα-5 was solved by nuclear magnetic resonance. A systematic functional evaluation of MeuNaTxα-1, -2, -4, and -5 was conducted by two-electrode voltage-clamp recordings on seven cloned mammalian voltage-gated sodium channels (Na(v)1.2 to Na(v)1.8) and the insect counterpart DmNa(v)1 expressed in Xenopus oocytes. Results show that all these four peptides slow inactivation of DmNa(v)1 and are inactive on Na(v)1.8 at micromolar concentrations. However, they exhibit differential specificity for the other six channel isoforms (Na(v)1.2 to Na(v)1.7), in which MeuNaTxα-4 shows no activity on these isoforms and thus represents the first Mesobuthus-derived insect-selective α-toxin identified so far with a half maximal effective concentration of 130 ± 2 nm on DmNa(v)1 and a half maximal lethal dose of about 200 pmol g(-1) on the insect Musca domestica; MeuNaTxα-2 only affects Na(v)1.4; MeuNaTxα-1 and MeuNaTxα-5 have a wider range of channel spectrum, the former active on Na(v)1.2, Na(v)1.3, Na(v)1.6, and Na(v)1.7, whereas the latter acting on Na(v)1.3-Na(v)1.7. Remarkably, MeuNaTxα-4 and MeuNaTxα-5 are two nearly identical peptides differing by only one point mutation at site 50 (A50V) but exhibit rather different channel subtype selectivity, highlighting a switch role of this site in altering the target specificity. By the maximum likelihood models of codon substitution, we detected nine positively selected sites (PSSs) that could be involved in functional diversification of Mesobuthus α-toxins. The PSSs include site 50 and other seven sites located in functional surfaces of α-toxins. This work represents the first thorough investigation of evolutionary diversification of α-toxins derived from a specific scorpion lineage from the perspectives of sequence, structure, function, and evolution.
On the Post-Compaction Evolution of Tensile Strength of Sodium Chloride-Starch Mixture Tablets.
Radojevic, Jovana; Zavaliangos, Antonios
2017-08-01
This study focuses on the evolution of mechanical behavior of starch and sodium chloride (NaCl) mixture tablets after compaction. This type of mixture has attracted attention in the past because such tablets exhibit lower tensile strengths than the ones of its individual components. Here we demonstrate that the strengths of NaCl-starch mixtures and NaCl tablets evolve after compaction in an opposite way. When stored at relative humidity of 60%, NaCl tablets strengthen with time, whereas NaCl-starch mixtures weaken. To explain this behavior, we propose that in the NaCl-starch mixture, the presence of 2 materials with significantly different elastic moduli leads to creation of tensile stresses at the stiffer NaCl-NaCl contacts. Such tensile stresses lead to a reduction in strength of the compacted mixtures by negating a local dissolution-reprecipitation mechanism, which strengthens the NaCl-NaCl in pure NaCl tablet. This effect is proven by experimental results from NaCl specimens diametrically loaded during storage. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.
Eichelberger, Maryna C; Morens, David M; Taubenberger, Jeffery K
2018-04-16
Neuraminidase (NA) plays an essential role in influenza virus replication, facilitating multicycle infection predominantly by releasing virions from infected cells. NA-inhibiting antibodies provide resistance to disease and NA-specific antibodies contribute to vaccine efficacy. The primary reason NA vaccine content and immunogenicity was not routinely measured in the past, was the lack of suitable assays to quantify NA and NA-specific antibodies. These are now available and with recent appreciation of its contribution to immunity, NA content of seasonal and pandemic vaccines is being considered. An added benefit of NA as a vaccine antigen is that many NA-specific antibodies bind to domains that are well conserved within a subtype, protecting against heterologous viruses. This suggests NA may be a good choice for inclusion in universal influenza vaccines. Published by Elsevier Ltd.
Moon, Chan Hong; Kim, Jung-Hwan; Zhao, Tiejun; Bae, Kyongtae Ty
2013-11-01
To develop quantitative dual-tuned (DT) (1) H/(23) Na MRI of human knee cartilage in vivo at 7 Tesla (T). A sensitive (23) Na transceiver array RF coil was developed at 7T. B1 fields generated by the transceiver array coil were characterized and corrected in the (23) Na images. Point spread function (PSF) of the (23) Na images was measured, and the signal decrease due to partial-volume-effect was compensated in [(23) Na] quantification of knee cartilage. SNR and [(23) Na] in anterior femoral cartilage were measured from seven healthy subjects. SNR of (23) Na image with the transceiver array coil was higher than that of birdcage coil. SNR in the cartilage at 2-mm isotropic resolution was 26.80 ± 3.69 (n = 7). B1 transmission and reception fields produced by the DT coil at 7T were similar to each other. Effective full-width-half-maximum of (23) Na image was ∼5 mm at 2-mm resolution. Mean [(23) Na] was 288.13 ± 29.50 mM (n = 7) in the anterior femoral cartilage of normal subjects. We developed a new high-sensitivity (23) Na RF coil for knee MRI at 7T. Our (1) H/(23) Na MRI allowed quantitative measurement of [(23) Na] in knee cartilage by measuring PSF and cartilage thickness from (23) Na and (1) H image, respectively. Copyright © 2013 Wiley Periodicals, Inc.
Györy, A Z; Roby, H
1977-01-01
1. With the aid of micropuncture techniques, proximal tubular transepithelial concentration differences for Na (deltaC Na) and chloride (deltaC Cl) were measured in kidney cortex slices at bathing fluid Na concentrations from 10 to 400 m-mole. kg-1. Tissue content of water, Na and K was also measured in such slices. Under steady-state conditions of zero net flux of NaCl and water, deltaC Na represents the sum of active Na transport, factored by the tubular permeability coefficient added to a component of flux due to electrical forces. 2. The relation between bathing fluid Na concentraton and deltaC Na appeared sigmoid in form suggesting an allosteric mechanism for the transport step. 3. Transtubular potential difference, calculated from transepithelial Cl distribution ratios, did not appear constant at the various bathing fluid Na concentrations. Correcting for the effect of these potential differences on the value of each deltaC Na did not convert the sigmoid transport curve to a hyperbolic one, confirming the suggested allosteric nature of the active Na transport step. 4. Intracellular Na content varied linearly with bathing fluid Na concentrations implying free entry of this cation into the cell. This also suggests that the sigmoid transport curve is related to the properties of the active Na transport pump. PMID:856986
Low-frequency Electronic Transport Noise in La2-xBaxCuO4 Nanowires
NASA Astrophysics Data System (ADS)
Weis, Adam; Xin, Yizhou; van Harlingen, Dale
2013-03-01
In the pseudogap regime, high temperature superconductors often exhibit electronic structure, such as charge stripes. Charge stripes pinned to disorder have been predicted to contribute to low-frequency resistance fluctuations when sample dimensions are comparable to the size of stripe domains (Carlson, 2006). We are extending our previous studies of resistance fluctuations in YBa2Cu3O7-δ (Bonetti, 2004; Caplan, 2010) to thin films of La-based cuprates expected to have a more stable stripe phase, particularly in the regime near 1/8-filling. We present measurements of the low-frequency electronic transport in La2-xBaxCuO4 nanowires fabricated by pulsed laser deposition and lithographic techniques. We discuss temperature dependence of the power spectral density and its relevance to correlated electron phases above Tc. This research was supported by the DOE-DMS under grant DE-FG02-07ER46453, through the Frederick Seitz Materials Research Laboratory at the University of Illinois at Urbana-Champaign.
Exploring plasmonic nanoantenna arrays as a platform for biosensing
NASA Astrophysics Data System (ADS)
Toussaint, Kimani C.
2017-08-01
In recent years, the PROBE Lab at the University of Illinois at Urbana-Champaign has made significant developments in plasmonic nanoantenna technology by more closely exploring the rich parameter space associated with these structures including geometry and material composition, as well as the optical excitation conditions. Indeed, plasmonic nanoantennas are attractive for a variety of potential applications in nanotechnology, biology, and photonics due to their ability to tightly confine and strongly enhance optical fields. This talk will discuss our work with arrays of Au bowtie nanoantennas (BNAs) with an emphasis on how their field enhancement properties could be harnessed for particle manipulation and sensing. We also present our work with pillar-supported BNAs (p-BNAs) and discuss their potential for sensing applications, particularly when adapted for response in the near-IR. The talk will conclude with a brief discussion of some of the future work pursued by the PROBE lab, including adapting BNAs for lab-on-a-chip applications.
T/R switch design for short-range measurements, part 6.1A
NASA Technical Reports Server (NTRS)
Yu, B.
1984-01-01
The positive intrinsic negative (PIN) diode switch which is designed to protect the receiver from burnout or damage on transmission and channel the echo signal to the receiver on reception is outlined. The receiver must be protected firmly. A schematic diagram of a transformer rectifier (TR-ATR) switch for the Urbana Radar is shown. The T/R switch consists of a half wavelength coaxial cavity with tuning condenser and PIN diodes. Two UM4300 PIN diodes were mounted between the inner and outer conductor. The dc biasing voltage required for the PIN diodes is supplied by a control circuit. On transmission, the PIN diodes are forward biased to about 0.5 amperes. On reception, about 10 volts reverse voltage is applied to the diodes, which produces an initial reverse current to speed the recovery time. The T/R switch characteristics are estimated and the result of testing at different peak transmitter powers from 410 kW to 1500 kW is shown.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nuqui, Reynaldo
This report summarizes the activities conducted under the DOE-OE funded project DEOE0000674, where ABB Inc. (ABB), in collaboration with University of Illinois at Urbana-Champaign (UIUC), Bonneville Power Administration (BPA), and Ameren-Illinois (Ameren-IL) pursued the development of a system of collaborative defense of electrical substation’s intelligent electronic devices against cyber-attacks (CODEF). An electrical substation with CODEF features will be more capable of mitigating cyber-attacks especially those that seek to control switching devices. It leverages the security extensions of IEC 61850 to empower existing devices to collaborate in identifying and blocking malicious intents to trip circuit breakers, mis-coordinate devices settings, even thoughmore » the commands and the measurements comply with correct syntax. The CODEF functions utilize the physics of electromagnetic systems, electric power engineering principles, and computer science to bring more in depth cyber defense closer to the protected substation devices.« less
The Singular Quest for a Universal Tree of Life
2013-01-01
Carl Woese developed a unique research program, based on rRNA, for discerning bacterial relationships and constructing a universal tree of life. Woese's interest in the evolution of the genetic code led to him to investigate the deep roots of evolution, develop the concept of the progenote, and conceive of the Archaea. In so doing, he and his colleagues at the University of Illinois in Urbana revolutionized microbiology and brought the classification of microbes into an evolutionary framework. Woese also provided definitive evidence for the role of symbiosis in the evolution of the eukaryotic cell while underscoring the importance of lateral gene transfer in microbial evolution. Woese and colleagues' proposal of three fundamental domains of life was brought forward in direct conflict with the prokaryote-eukaryote dichotomy. Together with several colleagues and associates, he brought together diverse evidence to support the rRNA evidence for the fundamentally tripartite nature of life. This paper aims to provide insight into his accomplishments, how he achieved them, and his place in the history of biology. PMID:24296570
Large-Scale Low-Boom Inlet Test Overview
NASA Technical Reports Server (NTRS)
Hirt, Stefanie
2011-01-01
This presentation provides a high level overview of the Large-Scale Low-Boom Inlet Test and was presented at the Fundamental Aeronautics 2011 Technical Conference. In October 2010 a low-boom supersonic inlet concept with flow control was tested in the 8'x6' supersonic wind tunnel at NASA Glenn Research Center (GRC). The primary objectives of the test were to evaluate the inlet stability and operability of a large-scale low-boom supersonic inlet concept by acquiring performance and flowfield validation data, as well as evaluate simple, passive, bleedless inlet boundary layer control options. During this effort two models were tested: a dual stream inlet intended to model potential flight hardware and a single stream design to study a zero-degree external cowl angle and to permit surface flow visualization of the vortex generator flow control on the internal centerbody surface. The tests were conducted by a team of researchers from NASA GRC, Gulfstream Aerospace Corporation, University of Illinois at Urbana-Champaign, and the University of Virginia
Owens, Brittany E; Carlton, Christopher E
2018-04-10
Two new species of Bibloplectus Reitter, 1881 are described from the Orlando Park Collection of Pselaphinae at the FMNH (Field Museum of Natural History, Chicago, IL, USA): Bibloplectus silvestris Owens and Carlton, new species (type locality, Urbana, IL, USA) and Bibloplectus wingi Owens and Carlton, new species (type locality, Shades State Park, IN, USA). Types of these new species were part of a series of specimens bearing unpublished Park manuscript names in both the pinned and slide collection at the FMNH. They bring the total number of species in the genus in eastern North America to twenty-three. Resolving these manuscript names adds to previous efforts to uncover elements of the hidden diversity of North American Bibloplectus from museum collections (Owens and Carlton 2016, Owens and Carlton 2017) and highlights the importance of close examination of the Orlando Park pselaphine collection as a valuable historic and taxonomic resource.
Mutations of Electrons as Constituents of Hadrons
NASA Astrophysics Data System (ADS)
Driscoll, R. B.
1997-04-01
Conjecture (C) 1: Coulomb-charged constituents of electron (e) are attracted to its barycentre by lepto-strong force F=K/r^2+f; f is stably perturbative for r < the "radius" of e. An exterior magnetic field (MF) with gradient (G) secularly perturbs the eccentricities but not the energies of the constituents' orbits, changing the spin (s) and magnetic moment (μ) of e. (C) 2: F coheres two or more e's dynamically with r approximately equal to the "radius" of e. The resulting MF and G at each e oscillate. Stable values of s and μ result for each e which differs from the atomic values. Binding energies change the masses of the e's. A hadron results. (C) 3: An e similarly may bind to a proton to form a Rutherford- Santilli neutron. The proton is negligibly mutated.(References: H. Dehmelt, Science 247, 539 (1990); T.E. Phipps, Jr., Heretical Verities (Classic Non-fiction Library, Urbana, 1986); R.M. Santilli, Hadronic Mechanics (Ukrainian Academy of Sciences, Kiev, 1995 and 1996), 3 volumes.)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Leakey, Andrew D. B.
This project funded the C 4 and CAM (crassulacean acid metabolism) Plant Biology 2013 symposium, held at the University of Illinois at Urbana-Champaign, IL, on August 6-9, 2013. The symposium brought together a diverse group of scientists to discuss the evolution, ecology, functional biology, genomics and biotechnological engineering of C 4 and CAM plants. These two groups of plants possess evolutionary modifications to their photosynthetic machinery that improve their performance in hot and dry conditions. Maize and pineapple are classic examples of C 4 and CAM plants, respectively. The meeting discussed how lessons learned from these groups of plants canmore » be harnessed to improve crop production of biofuel feedstocks in an era of global climate change. The interdisciplinary nature of the meeting meant that the delegation members typically do not collectively attend any one scientific society meeting. As a result, the symposium was a unique opportunity for knowledge transfer, initiation of new collaborations, and recruitment and exposure of early career scientists.« less
An investigation of turbulent scatter from the mesosphere as observed by coherent-scatter radar
NASA Technical Reports Server (NTRS)
Gibbs, K. P.; Bowhill, S. A.
1983-01-01
Turbulent scatter from he mesosphere is observed using the Urbana coherent-scatter radar. The variation in signal-to-noise ratio as a function of time-of-day is examined. The origin of scattering regions is investigated by comparing the variations in scattered power and Doppler velocity. Nighttime echoes are shown for periods of enhanced electron concentration. The spectrum of the returned signal is studied with a resolution of ten seconds. Spectral information is used to increase altitude resolution and observe the motion of scatterers. The expected variation in signal-to-noise ratio with solar flux is observed. It is found that variations in the scattered power generally do not correspond to the gravity waves which are simultaneously observed. Turbulent layers are observed at altitudes with high shear in the horizontal velocity and at altitudes with low shear. The ten-second resolution is necessary to distinguish meteor echoes from echoes produced by the advection of a scattering layer through the radar beam.
NASA Astrophysics Data System (ADS)
Unarunotai, Sakulsuk; Murata, Yuya; Chialvo, Cesar; Kim, Hoon-Sik; MacLaren, Scott; Mason, Nadya; Petrov, Ivan; Rogers, John
2010-03-01
An approach to produce graphene films by epitaxial growth on silicon carbide substrate is promising, but its current implementation requires the use of SiC as the device substrate. We present a simple method for transferring epitaxial sheets of graphene on SiC to other substrates. The graphene was grown on the (0001) face of 6H-SiC by thermal annealing in a hydrogen atmosphere. Transfer was accomplished using a peeling process with a bilayer film of Gold/polyimide, to yield graphene with square millimeters of coverage on the target substrate. Back gated field-effect transistors fabricated on oxidized silicon substrates with Cr/Au as source-drain electrodes exhibited ambipolar characteristics with hole mobilities of ˜100 cm^2/V-s, and negligible influence of resistance at the contacts. This work was supported by the U.S. DOE, under Award No. DE-FG02-07ER46471, through the Frederick Seitz Materials Research Laboratory at the University of Illinois at Urbana-Champaign.
NASA Technical Reports Server (NTRS)
Kane, Timothy J.; Qian, Jun; Scherrer, Daniel R.; Senft, Daniel C.; Pfenninger, W. Matthew; Papen, George C.; Gardner, Chester S.
1992-01-01
Meteoritic ablation in the upper atmosphere is the commonly accepted source of the mesospheric metals between 80 and 105 km. The vertical and temporal behavior of some of these metals can be probed with high accuracy and resolution using resonance fluorescence lidar techniques. Of considerable interest in recent years has been the sporadic and rapid formation of thin, dense enhancements in these metallic layers. Since late Mar. 1991, the UIUC CEDAR lidar system, located at the Urbana Atmospheric Observatory, has been routinely operating at the Fe resonance line of 372 nm in order to probe the mesospheric Fe layer. In Nov. 1991, the capability to investigate mesospheric Ca(+) at the resonance line of 393.4 nm was added. The lidar's eximer-pumped dye laser uses Exciton QUI laser dye dissolved in p-dioxane, which can lase at both the Fe and Ca(+) frequencies. Various aspects of this investigation are discussed.
Gender plays no role in student ability to perform on computer-based examinations.
Kies, Susan M; Williams, Benjamin D; Freund, Gregory G
2006-11-28
To see if there is a difference in performance when students switch from traditional paper-and-pencil examinations to computer-based examinations, and to determine whether there are gender differences in student performance in these two examination formats. This study involved first year medical students at the University of Illinois at Urbana-Champaign over three Academic Years 2002-03/2003-04 and 2003-05. Comparisons of student performance by overall class and gender were made. Specific comparisons within courses that utilized both the paper-and-pencil and computer formats were analyzed. Overall performance scores for students among the various Academic Years revealed no differences between exams given in the traditional pen-and-paper and computer formats. Further, when we looked specifically for gender differences in performance between these two testing formats, we found none. The format for examinations in the courses analyzed does not affect student performance. We find no evidence for gender differences in performance on exams on pen-and-paper or computer-based exams.
IMIRSEL: a secure music retrieval testing environment
NASA Astrophysics Data System (ADS)
Downie, John S.
2004-10-01
The Music Information Retrieval (MIR) and Music Digital Library (MDL) research communities have long noted the need for formal evaluation mechanisms. Issues concerning the unavailability of freely-available music materials have greatly hindered the creation of standardized test collections with which these communities could scientifically assess the strengths and weaknesses of their various music retrieval techniques. The International Music Information Retrieval Systems Evaluation Laboratory (IMIRSEL) is being developed at the University of Illinois at Urbana-Champaign (UIUC) specifically to overcome this hindrance to the scientific evaluation of MIR/MDL systems. Together with its subsidiary Human Use of Music Information Retrieval Systems (HUMIRS) project, IMIRSEL will allow MIR/MDL researchers access to the standardized large-scale collection of copyright-sensitive music materials and standardized test queries being housed at UIUC's National Center for Supercomputing Applications (NCSA). Virtual Research Labs (VRL), based upon NCSA's Data-to-Knowledge (D2K) tool set, are being developed through which MIR/MDL researchers will interact with the music materials under a "trusted code" security model.
Allan, Phoebe K.; Griffin, John M.; Darwiche, Ali; ...
2016-01-29
We use operando pair distribution function (PDF) analysis and ex situ 23Na magic-angle spinning solid-state nuclear magnetic resonance (MAS ssNMR) spectroscopy to gain insight into the alloying mechanism of high-capacity antimony anodes for sodium-ion batteries. Subtraction of the PDF of crystalline Na xSb phases from the total PDF, an approach constrained by chemical phase information gained from 23Na ssNMR in reference to relevant model compounds, identifies two previously uncharacterized intermediate species formed electrochemically; a-Na 3–xSb (x ≈ 0.4–0.5), a structure locally similar to crystalline Na 3Sb (c-Na 3Sb) but with significant numbers of sodium vacancies and a limited correlation length,more » and a-Na1.7Sb, a highly amorphous structure featuring some Sb–Sb bonding. The first sodiation breaks down the crystalline antimony to form first a-Na 3–xSb and, finally, crystalline Na 3Sb. Desodiation results in the formation of an electrode formed of a composite of crystalline and amorphous antimony networks. We link the different reactivity of these networks to a series of sequential sodiation reactions manifesting as a cascade of processes observed in the electrochemical profile of subsequent cycles. The amorphous network reacts at higher voltages reforming a-Na 1.7Sb, then a-Na 3–xSb, whereas lower potentials are required for the sodiation of crystalline antimony, which reacts to form a-Na 3–xSb without the formation of a-Na 1.7Sb. a-Na 3–xSb is converted to crystalline Na 3Sb at the end of the second discharge. In the end, we find no evidence of formation of NaSb. Variable temperature 23Na NMR experiments reveal significant sodium mobility within c-Na 3Sb; this is a possible contributing factor to the excellent rate performance of Sb anodes.« less
Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.
Subramanian, Nandhitha; Scopelitti, Amanda J; Carland, Jane E; Ryan, Renae M; O'Mara, Megan L; Vandenberg, Robert J
2016-01-01
The Na+/Cl- dependent glycine transporters GlyT1 and GlyT2 regulate synaptic glycine concentrations. Glycine transport by GlyT2 is coupled to the co-transport of three Na+ ions, whereas transport by GlyT1 is coupled to the co-transport of only two Na+ ions. These differences in ion-flux coupling determine their respective concentrating capacities and have a direct bearing on their functional roles in synaptic transmission. The crystal structures of the closely related bacterial Na+-dependent leucine transporter, LeuTAa, and the Drosophila dopamine transporter, dDAT, have allowed prediction of two Na+ binding sites in GlyT2, but the physical location of the third Na+ site in GlyT2 is unknown. A bacterial betaine transporter, BetP, has also been crystallized and shows structural similarity to LeuTAa. Although betaine transport by BetP is coupled to the co-transport of two Na+ ions, the first Na+ site is not conserved between BetP and LeuTAa, the so called Na1' site. We hypothesized that the third Na+ binding site (Na3 site) of GlyT2 corresponds to the BetP Na1' binding site. To identify the Na3 binding site of GlyT2, we performed molecular dynamics (MD) simulations. Surprisingly, a Na+ placed at the location consistent with the Na1' site of BetP spontaneously dissociated from its initial location and bound instead to a novel Na3 site. Using a combination of MD simulations of a comparative model of GlyT2 together with an analysis of the functional properties of wild type and mutant GlyTs we have identified an electrostatically favorable novel third Na+ binding site in GlyT2 formed by Trp263 and Met276 in TM3, Ala481 in TM6 and Glu648 in TM10.
Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2
Subramanian, Nandhitha; Scopelitti, Amanda J.; Carland, Jane E.; Ryan, Renae M.; O’Mara, Megan L.; Vandenberg, Robert J.
2016-01-01
The Na+/Cl- dependent glycine transporters GlyT1 and GlyT2 regulate synaptic glycine concentrations. Glycine transport by GlyT2 is coupled to the co-transport of three Na+ ions, whereas transport by GlyT1 is coupled to the co-transport of only two Na+ ions. These differences in ion-flux coupling determine their respective concentrating capacities and have a direct bearing on their functional roles in synaptic transmission. The crystal structures of the closely related bacterial Na+-dependent leucine transporter, LeuTAa, and the Drosophila dopamine transporter, dDAT, have allowed prediction of two Na+ binding sites in GlyT2, but the physical location of the third Na+ site in GlyT2 is unknown. A bacterial betaine transporter, BetP, has also been crystallized and shows structural similarity to LeuTAa. Although betaine transport by BetP is coupled to the co-transport of two Na+ ions, the first Na+ site is not conserved between BetP and LeuTAa, the so called Na1' site. We hypothesized that the third Na+ binding site (Na3 site) of GlyT2 corresponds to the BetP Na1' binding site. To identify the Na3 binding site of GlyT2, we performed molecular dynamics (MD) simulations. Surprisingly, a Na+ placed at the location consistent with the Na1' site of BetP spontaneously dissociated from its initial location and bound instead to a novel Na3 site. Using a combination of MD simulations of a comparative model of GlyT2 together with an analysis of the functional properties of wild type and mutant GlyTs we have identified an electrostatically favorable novel third Na+ binding site in GlyT2 formed by Trp263 and Met276 in TM3, Ala481 in TM6 and Glu648 in TM10. PMID:27337045
Vedovato, Natascia
2014-01-01
A single Na+/K+-ATPase pumps three Na+ outwards and two K+ inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na+ than K+ generates outward current across the cell membrane. Less well understood is the ability of Na+/K+ pumps to generate an inward current of protons. Originally noted in pumps deprived of external K+ and Na+ ions, as inward current at negative membrane potentials that becomes amplified when external pH is lowered, this proton current is generally viewed as an artifact of those unnatural conditions. We demonstrate here that this inward current also flows at physiological K+ and Na+ concentrations. We show that protons exploit ready reversibility of conformational changes associated with extracellular Na+ release from phosphorylated Na+/K+ pumps. Reversal of a subset of these transitions allows an extracellular proton to bind an acidic side chain and to be subsequently released to the cytoplasm. This back-step of phosphorylated Na+/K+ pumps that enables proton import is not required for completion of the 3 Na+/2 K+ transport cycle. However, the back-step occurs readily during Na+/K+ transport when external K+ ion binding and occlusion are delayed, and it occurs more frequently when lowered extracellular pH raises the probability of protonation of the externally accessible carboxylate side chain. The proton route passes through the Na+-selective binding site III and is distinct from the principal pathway traversed by the majority of transported Na+ and K+ ions that passes through binding site II. The inferred occurrence of Na+/K+ exchange and H+ import during the same conformational cycle of a single molecule identifies the Na+/K+ pump as a hybrid transporter. Whether Na+/K+ pump–mediated proton inflow may have any physiological or pathophysiological significance remains to be clarified. PMID:24688018
DOE Office of Scientific and Technical Information (OSTI.GOV)
Allan, Phoebe K.; Griffin, John M.; Darwiche, Ali
We use operando pair distribution function (PDF) analysis and ex situ 23Na magic-angle spinning solid-state nuclear magnetic resonance (MAS ssNMR) spectroscopy to gain insight into the alloying mechanism of high-capacity antimony anodes for sodium-ion batteries. Subtraction of the PDF of crystalline Na xSb phases from the total PDF, an approach constrained by chemical phase information gained from 23Na ssNMR in reference to relevant model compounds, identifies two previously uncharacterized intermediate species formed electrochemically; a-Na 3–xSb (x ≈ 0.4–0.5), a structure locally similar to crystalline Na 3Sb (c-Na 3Sb) but with significant numbers of sodium vacancies and a limited correlation length,more » and a-Na1.7Sb, a highly amorphous structure featuring some Sb–Sb bonding. The first sodiation breaks down the crystalline antimony to form first a-Na 3–xSb and, finally, crystalline Na 3Sb. Desodiation results in the formation of an electrode formed of a composite of crystalline and amorphous antimony networks. We link the different reactivity of these networks to a series of sequential sodiation reactions manifesting as a cascade of processes observed in the electrochemical profile of subsequent cycles. The amorphous network reacts at higher voltages reforming a-Na 1.7Sb, then a-Na 3–xSb, whereas lower potentials are required for the sodiation of crystalline antimony, which reacts to form a-Na 3–xSb without the formation of a-Na 1.7Sb. a-Na 3–xSb is converted to crystalline Na 3Sb at the end of the second discharge. In the end, we find no evidence of formation of NaSb. Variable temperature 23Na NMR experiments reveal significant sodium mobility within c-Na 3Sb; this is a possible contributing factor to the excellent rate performance of Sb anodes.« less
A Sensor Based on LiCl/NaA Zeolite Composites for Effective Humidity Sensing.
Zhang, Ying; Xiang, Hongyu; Sun, Liang; Xie, Qiuhong; Liu, Man; Chen, Yu; Ruan, Shengping
2018-03-01
LiCl/NaA zeolite composites were successfully prepared by doping 1 wt%, 2 wt%, 5 wt%, and 8 wt% of LiCl into NaA zeolite. The humidity sensing properties of LiCl/NaA composites were investigated among 11% 95% relative humidity (RH). The LiCl/NaA composites exhibited better humidity sensing properties than pure NaA zeolite. The sensor made by 2 wt% Li-doped NaA zeolite possesses the best linearly in the whole RH. These results demonstrate that the LiCl/NaA composites have the potential application in humidity sensing.
2012-10-17
0 0 ~60 ~90 Helicopters n/a n/a n/a n/a ~34 ~153 ~157 Subtotal above aircraft n/a n/a n/a n/a ~179 ~468 ~ 505 Source: Prepared by CRS. Source for...Congressional Research Service 87 The Air-Sea Battle Concept centers on networked, integrated, attack-in-depth to disrupt, destroy and defeat ( NIA -D3) A2/AD...of U.S. forces; and defeat an adversary’s employed weapons to preserve essential U.S. Joint forces and their enablers. Through NIA -D3, air and naval
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aboussatar, Mohamed; Laboratoire de Physico-Chimie de l’État Solide, Faculté des Sciences de Sfax, Université de Sfax, BP 1171, 3000 Sfax; Mbarek, Aïcha
Isothermal sections of the diagram representing phase relationships in the NaF-CdO-NaPO{sub 3} system have been investigated by solid state reactions and powder X-ray diffraction. This phase diagram investigation confirms the polymorphism of the NaCdPO{sub 4} side component and the structure of the ß high temperature polymorph (orthorhombic, space group Pnma and unit cell parameters a=9.3118(2), b=7.0459(1), c=5.1849(1) Å has been refined. A new fluorophosphate, Na{sub 2}CdPO{sub 4}F, has been discovered and its crystal structure determined and refined from powder X-ray diffraction data. It exhibits a new 3D structure with orthorhombic symmetry, space group Pnma and unit cell parameters a=5.3731(1), b=6.8530(1),more » c=12.2691(2) Å. The structure is closely related to those of the high temperature polymorph of the nacaphite Na{sub 2}CaPO{sub 4}F and the fluorosilicate Ca{sub 2}NaSiO{sub 4}F but differs essentially in the cationic repartition since the structure is fully ordered with one Na site (8d) and one Cd site (4c). Relationships with other Na{sub 2}M{sup II}PO{sub 4}F (M{sup II}=Mg, Ca, Mn, Fe, Co, Ni) have been examined and the crystal-chemical and topographical analysis of these fluorophosphates is briefly reviewed. IR, Raman, optical and {sup 19}F, {sup 23}Na, {sup 31}P MAS NMR characterizations of Na{sub 2}CdPO{sub 4}F have been investigated. - Graphical abstract: The structure of the compound Na{sub 2}CdPO{sub 4}F, discovered during the study of the phase relationships in the NaF-CdO-NaPO{sub 3} system, has been determined and compared with other Na{sub 2}M{sup II}PO{sub 4}F fluorophosphates. - Highlights: • XRD analysis of the isothermal section of the NaF-CdO-NaPO{sub 3} system at 923 K. • Rietveld refinement of the high temperature polymorph β-NaCdPO{sub 4}. • Crystal structure of the new Na{sub 2}CdPO{sub 4}F fluorophosphate determined from powder XRD. • Crystal structure - composition relationships of Na{sub 2}M{sup II}PO{sub 4}F compounds are reviewed. • IR, Raman, optical and {sup 19}F, {sup 23}Na, {sup 31}P MAS NMR characterizations of Na{sub 2}CdPO{sub 4}F.« less
Kostyrko, Vitaly A.; Bertsova, Yulia V.; Serebryakova, Marina V.; Baykov, Alexander A.
2015-01-01
ABSTRACT Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) catalyzes electron transfer from NADH to ubiquinone in the bacterial respiratory chain, coupled with Na+ translocation across the membrane. Na+-NQR maturation involves covalent attachment of flavin mononucleotide (FMN) residues, catalyzed by flavin transferase encoded by the nqr-associated apbE gene. Analysis of complete bacterial genomes has revealed another putative gene (duf539, here renamed nqrM) that usually follows the apbE gene and is present only in Na+-NQR-containing bacteria. Expression of the Vibrio harveyi nqr operon alone or with the associated apbE gene in Escherichia coli, which lacks its own Na+-NQR, resulted in an enzyme incapable of Na+-dependent NADH or reduced nicotinamide hypoxanthine dinucleotide (dNADH) oxidation. However, fully functional Na+-NQR was restored when these genes were coexpressed with the V. harveyi nqrM gene. Furthermore, nqrM lesions in Klebsiella pneumoniae and V. harveyi prevented production of functional Na+-NQR, which could be recovered by an nqrM-containing plasmid. The Na+-NQR complex isolated from the nqrM-deficient strain of V. harveyi lacks several subunits, indicating that nqrM is necessary for Na+-NQR assembly. The protein product of the nqrM gene, NqrM, contains a single putative transmembrane α-helix and four conserved Cys residues. Mutating one of these residues (Cys33 in V. harveyi NqrM) to Ser completely prevented Na+-NQR maturation, whereas mutating any other Cys residue only decreased the yield of the mature protein. These findings identify NqrM as the second specific maturation factor of Na+-NQR in proteobacteria, which is presumably involved in the delivery of Fe to form the (Cys)4[Fe] center between subunits NqrD and NqrE. IMPORTANCE Na+-translocating NADH:quinone oxidoreductase complex (Na+-NQR) is a unique primary Na+ pump believed to enhance the vitality of many bacteria, including important pathogens such as Vibrio cholerae, Vibrio parahaemolyticus, Haemophilus influenzae, Neisseria gonorrhoeae, Pasteurella multocida, Porphyromonas gingivalis, Enterobacter aerogenes, and Yersinia pestis. Production of Na+-NQR in bacteria requires Na+-NQR-specific maturation factors. We earlier identified one such factor (ApbE) that covalently attaches flavin residues to Na+-NQR. Here we identify the other protein factor, designated NqrM, and show that NqrM and ApbE suffice to produce functional Na+-NQR from the Vibrio harveyi nqr operon. NqrM may be involved in Fe delivery to a unique Cys4[Fe] center during Na+-NQR assembly. Besides highlighting Na+-NQR biogenesis, these findings suggest a novel drug target to combat Na+-NQR-containing bacteria. PMID:26644436
Analysis of bakery products by laser-induced breakdown spectroscopy.
Bilge, Gonca; Boyacı, İsmail Hakkı; Eseller, Kemal Efe; Tamer, Uğur; Çakır, Serhat
2015-08-15
In this study, we focused on the detection of Na in bakery products by using laser-induced breakdown spectroscopy (LIBS) as a quick and simple method. LIBS experiments were performed to examine the Na at 589 nm to quantify NaCl. A series of standard bread sample pellets containing various concentrations of NaCl (0.025-3.5%) were used to construct the calibration curves and to determine the detection limits of the measurements. Calibration graphs were drawn to indicate functions of NaCl and Na concentrations, which showed good linearity in the range of 0.025-3.5% NaCl and 0.01-1.4% Na concentrations with correlation coefficients (R(2)) values greater than 0.98 and 0.96. The obtained detection limits for NaCl and Na were 175 and 69 ppm, respectively. Performed experimental studies showed that LIBS is a convenient method for commercial bakery products to quantify NaCl concentrations as a rapid and in situ technique. Copyright © 2015 Elsevier Ltd. All rights reserved.
Novel duplex vapor-electrochemical method for silicon solar cells
NASA Technical Reports Server (NTRS)
Nanis, L.; Sanjurjo, A.; Westphal, S.
1979-01-01
Optimization studies were carried out for the SiF4-Na reaction with solid Na feed. The goals of the study were the consistent production of high purity reaction products and the gathering of relevant information needed to scale-up the reactor. Parameters studied include: (1) effect of surface to volume ratio of Na slices on the extent of reaction; (2) effect of Na surface oxidation on the extent of reaction; (3) effect of external heating on the extent of SiF4-Na reaction; (4) effect of Na slice addition rate on extent of the reaction; and (5) SiF4-Na reaction - high pressure experiments. An investigation was also made of the possible role played by NaF as a fluxing agent during the separation of silicon by melting of the reaction product (Si + NaF) mixture. Since silicon can be produced by the thermite reaction between Na2SiF6 and Na, studies were initiated to gather information on parameters which control the efficiency of the thermite reaction.
Interaction of NaOH solutions with silica surfaces
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rimsza, Jessica M.; Jones, Reese E.; Criscenti, Louise J.
Sodium adsorption on silica surfaces depends on the solution counter-ion. Here, we use NaOH solutions to investigate basic environments. Sodium adsorption on hydroxylated silica surfaces from NaOH solutions were investigated through molecular dynamics with a dissociative force field, allowing for the development of secondary molecular species. Furthermore, across the NaOH concentrations (0.01 M – 1.0 M), ~50% of the Na + ions were concentrated in the surface region, developing silica surface charges between –0.01 C/m 2 (0.01 M NaOH) and –0.76 C/m 2 (1.0 M NaOH) due to surface site deprotonation. Five inner-sphere adsorption complexes were identified, including monodentate, bidentate,more » and tridentate configurations and two additional structures, with Na + ions coordinated by bridging oxygen and hydroxyl groups or water molecules. Coordination of Na + ions by bridging oxygen atoms indicates partial or complete incorporation of Na + ions into the silica surface. Residence time analysis identified that Na + ions coordinated by bridging oxygen atoms stayed adsorbed onto the surface four times longer than the mono/bi/tridentate species, indicating formation of relatively stable and persistent Na + ion adsorption structures. Such inner-sphere complexes form only at NaOH concentrations of > 0.5 M. Na + adsorption and lifetimes have implications for the stability of silica surfaces.« less
Interaction of NaOH solutions with silica surfaces
Rimsza, Jessica M.; Jones, Reese E.; Criscenti, Louise J.
2018-01-16
Sodium adsorption on silica surfaces depends on the solution counter-ion. Here, we use NaOH solutions to investigate basic environments. Sodium adsorption on hydroxylated silica surfaces from NaOH solutions were investigated through molecular dynamics with a dissociative force field, allowing for the development of secondary molecular species. Furthermore, across the NaOH concentrations (0.01 M – 1.0 M), ~50% of the Na + ions were concentrated in the surface region, developing silica surface charges between –0.01 C/m 2 (0.01 M NaOH) and –0.76 C/m 2 (1.0 M NaOH) due to surface site deprotonation. Five inner-sphere adsorption complexes were identified, including monodentate, bidentate,more » and tridentate configurations and two additional structures, with Na + ions coordinated by bridging oxygen and hydroxyl groups or water molecules. Coordination of Na + ions by bridging oxygen atoms indicates partial or complete incorporation of Na + ions into the silica surface. Residence time analysis identified that Na + ions coordinated by bridging oxygen atoms stayed adsorbed onto the surface four times longer than the mono/bi/tridentate species, indicating formation of relatively stable and persistent Na + ion adsorption structures. Such inner-sphere complexes form only at NaOH concentrations of > 0.5 M. Na + adsorption and lifetimes have implications for the stability of silica surfaces.« less
Comprehensive Insights into the Reactivity of Electrolytes Based on Sodium Ions.
Eshetu, Gebrekidan Gebresilassie; Grugeon, Sylvie; Kim, Huikyong; Jeong, Sangsik; Wu, Liming; Gachot, Gregory; Laruelle, Stephane; Armand, Michel; Passerini, Stefano
2016-03-08
We report a systematic investigation of Na-based electrolytes that comprise various NaX [X=hexafluorophosphate (PF6 ), perchlorate (ClO4 ), bis(trifluoromethanesulfonyl)imide (TFSI), fluorosulfonyl-(trifluoromethanesulfonyl)imide (FTFSI), and bis(fluorosulfonyl)imide (FSI)] salts and solvent mixtures [ethylene carbonate (EC)/dimethyl carbonate (DMC), EC/diethyl carbonate (DEC), and EC/propylene carbonate (PC)] with respect to the Al current collector stability, formation of soluble degradation compounds, reactivity towards sodiated hard carbon (Nax -HC), and solid-electrolyte interphase (SEI) layer formation. Cyclic voltammetry demonstrates that the stability of Al is highly influenced by the nature of the anions, solvents, and additives. GC-MS analysis reveals that the formation of SEI telltales depends on the nature of the linear alkyl carbonates and the battery chemistry (Li(+) vs. Na(+) ). FTIR spectroscopy shows that double alkyl carbonates are the main components of the SEI layer on Nax -HC. In the presence of Na salts, EC/DMC and EC/DEC presented a higher reactivity towards Nax -HC than EC/PC. For a fixed solvent mixture, the onset temperature follows the sequence NaClO4
Hettinger, Thomas P.; Savoy, Lawrence D.; Frank, Marion E.
2012-01-01
Component signaling in taste mixtures containing both beneficial and dangerous chemicals depends on peripheral processing. Unidirectional mixture suppression of chorda tympani (CT) nerve responses to sucrose by quinine and acid is documented for golden hamsters (Mesocricetus auratus). To investigate mixtures of NaCl and acids, we recorded multifiber responses to 50 mM NaCl, 1 and 3 mM citric acid and acetic acid, 250 μM citric acid, 20 mM acetic acid, and all binary combinations of each acid with NaCl (with and without 30 μM amiloride added). By blocking epithelial Na+ channels, amiloride treatment separated amiloride-sensitive NaCl-specific responses from amiloride-insensitive electrolyte-generalist responses, which encompass all of the CT response to the acids as well as responses to NaCl. Like CT sucrose responses, the amiloride-sensitive NaCl responses were suppressed by as much as 50% by citric acid (P = 0.001). The amiloride-insensitive electrolyte-generalist responses to NaCl + acid mixtures approximated the sum of NaCl and acid component responses. Thus, although NaCl-specific responses to NaCl were weakened in NaCl–acid mixtures, electrolyte-generalist responses to acid and NaCl, which tastes KCl-like, were transmitted undiminished in intensity to the central nervous system. The 2 distinct CT pathways are consistent with known rodent behavioral discriminations. PMID:22451526
Nieves-González, Aniel; Clausen, Chris; Marcano, Mariano; Layton, Anita T; Layton, Harold E; Moore, Leon C
2013-03-15
Thick ascending limb (TAL) cells are capable of reducing tubular fluid Na(+) concentration to as low as ~25 mM, and yet they are thought to transport Na(+) efficiently owing to passive paracellular Na(+) absorption. Transport efficiency in the TAL is of particular importance in the outer medulla where O(2) availability is limited by low blood flow. We used a mathematical model of a TAL cell to estimate the efficiency of Na(+) transport and to examine how tubular dilution and cell volume regulation influence transport efficiency. The TAL cell model represents 13 major solutes and the associated transporters and channels; model equations are based on mass conservation and electroneutrality constraints. We analyzed TAL transport in cells with conditions relevant to the inner stripe of the outer medulla, the cortico-medullary junction, and the distal cortical TAL. At each location Na(+) transport efficiency was computed as functions of changes in luminal NaCl concentration ([NaCl]), [K(+)], [NH(4)(+)], junctional Na(+) permeability, and apical K(+) permeability. Na(+) transport efficiency was calculated as the ratio of total net Na(+) transport to transcellular Na(+) transport. Transport efficiency is predicted to be highest at the cortico-medullary boundary where the transepithelial Na(+) gradient is the smallest. Transport efficiency is lowest in the cortex where luminal [NaCl] approaches static head.
An RNA-Cleaving Catalytic DNA Accelerated by Freezing.
Yu, Tianmeng; Zhou, Wenhu; Liu, Juewen
2018-05-18
The EtNa DNAzyme was isolated during the isopropanol precipitation step of an in vitro selection effort. Although inactive with the intended cofactor, its RNA cleavage activity was observed under a few conditions. With Na + , EtNa was highly active in ∼50 % ethanol, whereas in water, it was highly active with Ca 2+ . In this work, we showed that the EtNa DNAzyme was accelerated by freezing in water in the presence of Na + . The apparent K d value reached 6.2 mm Na + under the frozen condition, over 20 times tighter than that in water at room temperature. With 10 mm Na + , EtNa had a cleavage rate of 0.12 h -1 after freezing at -20 °C. This effect was unique to EtNa, as all other tested DNAzymes were inhibited by freezing except for the Na + -specific NaA43. Freezing also inhibited EtNa if Ca 2+ was used. We attributed this to the concentrations of EtNa and Na + in the micropockets between ice crystals, but divalent metals might misfold DNA. Overall, we have systematically studied the effect of freezing on the RNA-cleavage activity of DNAzymes. The DNAzyme sequence and the metal ion species are both crucial to determine the effect of freezing. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Validation of estimating food intake in gray wolves by 22Na turnover
DelGiudice, G.D.; Duquette, L.S.; Seal, U.S.; Mech, L.D.
1991-01-01
We studied 22sodium (22Na) turnover as a means of estimating food intake in 6 captive, adult gray wolves (Canis lupus) (2 F, 4 M) over a 31-day feeding period. Wolves were fed white-tailed deer (Odocoileus virginianus) meat only. Mean mass-specific exchangeable Na pool was 44.8 .+-. 0.7 mEq/kg; there was no differeence between males and females. Total exchangeable Na was related (r2 = 0.85, P < 0.009) to body mass. Overall, 22Na turnover overestimated Na intake by 9.8 .+-. 2.4% after 32 days. Actual Na intake was similar in males and females; however, Na turnover (P < 0.05) and the discrepancy (P < 0.01) between turnover and actual Na intake were greater in females than males. From Day 8 to the end of the study, the absolute difference (mEq) between Na intake and Na turnover remained stable. Sodium turnover (mEq/kg/day) was a reliable (r2 = 0.91, P < 0.001) estimator of food consumption (g/kg/day) in wolves over a 32-day period. Sampling blood and weighing wolves every 1-4 days permitted identification of several potential sources of error, including changes in size of exchangeable Na pools, exchange of 22Na with gastrointestinal and bone Na, and rapid loss of the isotope by urinary excretion.
Møller, Inge S; Gilliham, Matthew; Jha, Deepa; Mayo, Gwenda M; Roy, Stuart J; Coates, Juliet C; Haseloff, Jim; Tester, Mark
2009-07-01
Soil salinity affects large areas of cultivated land, causing significant reductions in crop yield globally. The Na+ toxicity of many crop plants is correlated with overaccumulation of Na+ in the shoot. We have previously suggested that the engineering of Na+ exclusion from the shoot could be achieved through an alteration of plasma membrane Na+ transport processes in the root, if these alterations were cell type specific. Here, it is shown that expression of the Na+ transporter HKT1;1 in the mature root stele of Arabidopsis thaliana decreases Na+ accumulation in the shoot by 37 to 64%. The expression of HKT1;1 specifically in the mature root stele is achieved using an enhancer trap expression system for specific and strong overexpression. The effect in the shoot is caused by the increased influx, mediated by HKT1;1, of Na+ into stelar root cells, which is demonstrated in planta and leads to a reduction of root-to-shoot transfer of Na+. Plants with reduced shoot Na+ also have increased salinity tolerance. By contrast, plants constitutively expressing HKT1;1 driven by the cauliflower mosaic virus 35S promoter accumulated high shoot Na+ and grew poorly. Our results demonstrate that the modification of a specific Na+ transport process in specific cell types can reduce shoot Na+ accumulation, an important component of salinity tolerance of many higher plants.
Na and K Dependence of the Na/K Pump in Cystic Fibrosis Fibroblasts
NASA Astrophysics Data System (ADS)
Reznik, Vivian M.; Schneider, Jerry A.; Mendoza, Stanley A.
1981-11-01
The Na and K dependence of the Na/K pump was measured in skin fibroblasts from patients with cystic fibrosis and age/sex-matched controls. Under basal conditions, there was no difference between control and cystic fibrosis cells in protein per cell, intracellular Na and K content, or Na/K pump activity (measured as ouabain-sensitive 86Rb uptake). There was no difference in the Na dependence of the Na/K pump between cystic fibrosis cells and control cells. In cells from patients with cystic fibrosis, the Na/K pump had a significantly lower affinity for K (Km = 1.6 mM) when compared to normals (Km = 0.9 mM). This difference was demonstrated by using two independent experimental designs.
Scheibener, S A; Richardi, V S; Buchwalter, D B
2016-02-01
The importance of insects in freshwater ecosystems has led to their extensive use in ecological monitoring programs. As freshwater systems are increasingly challenged by salinization and metal contamination, it is important to understand fundamental aspects of aquatic insect physiology (e.g., osmoregulatory processes) that contribute to insect responses to these stressors. Here we compared the uptake dynamics of Na as NaCl, NaHCO3 and Na2SO4 in the caddisfly Hydropsyche betteni across a range of Na concentrations (0.06-15.22 mM) encompassing the vast majority of North American freshwater ecosystems. Sulfate as the major anion resulted in decreased Na uptake rates relative to the chloride and bicarbonate salts. A comparison of Na (as NaHCO3) turnover rates in the caddisfly Hydropsyche sparna and the mayfly Maccaffertium sp. revealed different patterns in the 2 species. Both species appeared to tightly regulate their whole body sodium concentrations (at ∼47±1.8 μmol/g wet wt) across a range of Na concentrations (0.06-15.22 mM) over 7 days. However, at the highest Na concentration (15.22 mM), Na uptake rates in H. sparna (419.1 μM Na g(-1) hr(-1) wet wt) appeared close to saturation while Na uptake rates in Maccaffertium sp. were considerably faster (715 g μM Na g(-1) hr(-1) wet wt) and appeared to not be close to saturation. Na efflux studies in H. sparna revealed that loss rates are commensurate with uptake rates and are responsive to changes in water Na concentrations. A comparison of Na uptake rates (at 0.57 mM Na) across 9 species representing 4 major orders (Ephemeroptera, Plecoptera, Trichoptera and Diptera) demonstrated profound physiological differences across species after accounting for the influence of body weight. Faster Na uptake rates were associated with species described as being sensitive to salinization in field studies. The metals silver (Ag) and copper (Cu), known to be antagonistic to Na uptake in other aquatic taxa did not generally exhibit this effect in aquatic insects. Ag only reduced Na uptake at extremely high concentrations, while Cu generally stimulated Na uptake in aquatic insects, rather than suppress it. These results help explain the lack of insect responses to dissolved metal exposures in traditional toxicity testing and highlight the need to better understand fundamental physiological processes in this ecologically important faunal group. Copyright © 2015 Elsevier B.V. All rights reserved.
Amaral, C C F; Ormiga, F; Boldrini, L C; Miranda, P G; Mendonça, T A; Granjeiro, J M; Gomes, J A C P
2018-05-15
To evaluate the effects of the [NaF 12 g/L + NaCl 1 g/L] solution used in the electrochemical dissolution process of fractured endodontic files, as well as its NiTi-containing product, on dentine hardness, topography and human fibroblast viability. Sixty single-rooted human teeth were evaluated for dentine microhardness using the Vickers hardness test and the area and number of dentinal tubules by scanning electron microscopy. The samples were divided according to the dentine surface treatment: distilled water; 17% EDTA; [NaF 12 g/L + NaCl 1 g/L]; and 17% EDTA + [NaF 12 g/L + NaCl 1 g/L]. Thirty-six single-rooted human teeth were divided according to the irrigation protocol: Dulbecco's Modified Eagle's Medium + 10% fetal bovine serum; 5.25% NaOCl; [NaF 12 g/L + NaCl 1 g/L]; and [NaF 12 g/L + NaCl 1 g/L+NiTi]. The extracts in contact with the apical foramen were used in the MTT assay to evaluate human fibroblast viability, with dilutions of 100, 50, 25 and 12.5%. Statistical tests used were paired t-tests, one-way ANOVA, Tukey's test, Kruskal-Wallis test and Dunn's post-test. The [NaF 12 g/L + NaCl 1 g/L] solution did not modify the dentine microhardness or the average dentinal tubule area. However, the EDTA induced changes in the dentine structure and microhardness (p<0.05). The [NaF 12 g/L + NaCl 1 g/L] solution and its NiTi-containing product had lower cytotoxicity than NaOCl at dilutions of 25% and 50% (p<0.01). The [NaF 12 g/L + NaCl 1 g/L] solution did not alter dentine microhardness or damage the dentine structure. It also demonstrated lower cytotoxicity than NaOCl. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
Ma, Xuchu; Xu, Fen; Atkins, Tonya; Goforth, Andrea M.; Neiner, Doinita; Navrotsky, Alexandra; Kauzlarich, Susan M.
2010-01-01
Na4Si4 and Na4Ge4 are ideal chemical precursors for inorganic clathrate structures, clusters, and nanocrystals. The monoclinic Zintl phases, Na4Si4 and Na4Ge4, contain isolated homo-tetrahedranide [Si4]4− and [Ge4]4− clusters surrounded by alkali metal cations. In this study, a simple scalable route has been applied to prepare Zintl phases of composition Na4Si4 and Na4Ge4 using the reaction between NaH and Si or Ge at low temperature (420 °C for Na4Si4 and 270 °C for Na4Ge4). The method was also applied to K4Ge4, using KH and Ge as raw materials, to show the versatility of this approach. The influence of specific reaction conditions on the purity of these Zintl phases has been studied by controlling five factors: the method of reagent mixing (manual or ball milled), the stoichiometry between raw materials, the reaction temperature, the heating time and the gas flow rate. Moderate ball-milling and excess NaH or KH facilitate the formation of pure Na4Si4, Na4Ge4 or K4Ge4 at 420 °C (Na4Si4) or 270 °C (both M4Ge4 compounds, M = Na, K). TG/DSC analysis of the reaction of NaH and Ge indicates that ball milling reduces the temperature for reaction and confirms the formation temperature. This method provides large quantities of high quality Na4Si4 and Na4Ge4 without the need for specialized laboratory equipment, such as Schlenk lines, niobium/tantalum containers, or an arc welder, thereby expanding the accessibility and chemical utility of these phases by making them more convenient to prepare. This new synthetic method may also be extended to lithium-containing Zintl phases (LiH is commercially available) as well as to alkali metal-tetrel Zintl compounds of other compositions, e.g. K4Ge9. PMID:19921060
Balashov, Sergei P.; Imasheva, Eleonora S.; Dioumaev, Andrei K.; ...
2014-11-06
A group of microbial retinal proteins most closely related to the proton pump xanthorhodopsin has a novel sequence motif and a novel function. Instead of, or in addition to, proton transport, they perform light-driven sodium ion transport, as reported for one representative of this group (KR2) from Krokinobacter. In this paper, we examine a similar protein, GLR from Gillisia limnaea, expressed in Escherichia coli, which shares some properties with KR2 but transports only Na +. The absorption spectrum of GLR is insensitive to Na + at concentrations of ≤3 M. However, very low concentrations of Na + cause profound differencesmore » in the decay and rise time of photocycle intermediates, consistent with a switch from a “Na +-independent” to a “Na +-dependent” photocycle (or photocycle branch) at ~60 μM Na +. The rates of photocycle steps in the latter, but not the former, are linearly dependent on Na + concentration. This suggests that a high-affinity Na + binding site is created transiently after photoexcitation, and entry of Na + from the bulk to this site redirects the course of events in the remainder of the cycle. A greater concentration of Na + is needed for switching the reaction path at lower pH. The data suggest therefore competition between H + and Na + to determine the two alternative pathways. The idea that a Na + binding site can be created at the Schiff base counterion is supported by the finding that upon perturbation of this region in the D251E mutant, Na + binds without photoexcitation. Furthermore, binding of Na+ to the mutant shifts the chromophore maximum to the red like that of H +, which occurs in the photocycle of the wild type.« less
Mechanistic origin of low polarization in aprotic Na-O2 batteries.
Ma, Shunchao; McKee, William C; Wang, Jiawei; Guo, Limin; Jansen, Martin; Xu, Ye; Peng, Zhangquan
2017-05-21
Research interest in aprotic sodium-air (Na-O 2 ) batteries is growing because of their considerably high theoretical specific energy and potentially better reversibility than lithium-air (Li-O 2 ) batteries. While Li 2 O 2 has been unequivocally identified as the major discharge product in Li-O 2 batteries containing relatively stable electrolytes, a multitude of discharge products, including NaO 2 , Na 2 O 2 and Na 2 O 2 ·2H 2 O, have been reported for Na-O 2 batteries and the corresponding cathodic electrochemistry remains incompletely understood. Herein, we provide molecular-level insights into the key mechanistic differences between Na-O 2 and Li-O 2 batteries based on gold electrodes in strictly dry, aprotic dimethyl sulfoxide electrolytes through a combination of in situ spectroelectrochemistry and density functional theory based modeling. While like Li-O 2 batteries, the formation of oxygen reduction products (i.e., O 2 - , NaO 2 and Na 2 O 2 ) in Na-O 2 batteries depends critically on the electrode potential, two factors lead to a better reversibility of Na-O 2 electrochemistry, and are therefore highly beneficial to a viable rechargeable metal-air battery design: (i) only O 2 - and NaO 2 , and no Na 2 O 2 , form down to as low as ∼1.5 V vs. Na/Na + during discharge; (ii) solid NaO 2 is quite soluble and its formation and oxidation can proceed through micro-reversible EC (a chemical reaction of the product after the electron transfer) and CE (a chemical reaction preceding the electron transfer) processes, respectively, with O 2 - as the key intermediate.
Irving, Roy M.; Pinkerton, Marie E.; Elfarra, Adnan A.
2012-01-01
N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine (NA-DCVC) has been detected in the urine of humans exposed to trichloroethylene and its related sulfoxide, N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide (NA-DCVCS), has been detected as hemoglobin adducts in blood of rats dosed with S-(1,2-dichlorovinyl)-L-cysteine (DCVC) or S-(1,2-dichlorovinyl)-L-cysteine sulfoxide (DCVCS). Because the in vivo nephrotoxicity of NA-DCVCS was unknown, in this study, male Sprague-Dawley rats were dosed (i.p.) with 230 µmol/kg b.w. NA-DCVCS or its potential precursors, DCVCS or NA-DCVC. At 24 h post treatment, rats given NA-DCVC or NA-DCVCS exhibited kidney lesions and effects on renal function distinct from those caused by DCVCS. NA-DCVC and NA-DCVCS primarily affected the cortico-medullary proximal tubules (S2–S3 segments) while DCVCS primarily affected the outer cortical proximal tubules (S1–S2 segments). When NA-DCVCS or DCVCS was incubated with GSH in phosphate buffer pH 7.4 at 37°C, the corresponding glutathione conjugates were detected, but NA-DCVC was not reactive with GSH. Because NA-DCVCS exhibited a longer half-life than DCVCS and addition of rat liver cytosol enhanced GSH conjugate formation, catalysis of GSH conjugate formation by the liver could explain the lower toxicity of NA-DCVCS in comparison with DCVCS. Collectively, these results provide clear evidence that NA-DCVCS formation could play a significant role in DCVC, NA-DCVC, and trichloroethylene nephrotoxicity. They also suggest a role for hepatic metabolism in the mechanism of NA-DCVC nephrotoxicity. PMID:23253325
Irving, Roy M; Pinkerton, Marie E; Elfarra, Adnan A
2013-02-15
N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine (NA-DCVC) has been detected in the urine of humans exposed to trichloroethylene and its related sulfoxide, N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide (NA-DCVCS), has been detected as hemoglobin adducts in blood of rats dosed with S-(1,2-dichlorovinyl)-L-cysteine (DCVC) or S-(1,2-dichlorovinyl)-L-cysteine sulfoxide (DCVCS). Because the in vivo nephrotoxicity of NA-DCVCS was unknown, in this study, male Sprague-Dawley rats were dosed (i.p.) with 230 μmol/kg b.w. NA-DCVCS or its potential precursors, DCVCS or NA-DCVC. At 24 h post treatment, rats given NA-DCVC or NA-DCVCS exhibited kidney lesions and effects on renal function distinct from those caused by DCVCS. NA-DCVC and NA-DCVCS primarily affected the cortico-medullary proximal tubules (S(2)-S(3) segments) while DCVCS primarily affected the outer cortical proximal tubules (S(1)-S(2) segments). When NA-DCVCS or DCVCS was incubated with GSH in phosphate buffer pH 7.4 at 37°C, the corresponding glutathione conjugates were detected, but NA-DCVC was not reactive with GSH. Because NA-DCVCS exhibited a longer half-life than DCVCS and addition of rat liver cytosol enhanced GSH conjugate formation, catalysis of GSH conjugate formation by the liver could explain the lower toxicity of NA-DCVCS in comparison with DCVCS. Collectively, these results provide clear evidence that NA-DCVCS formation could play a significant role in DCVC, NA-DCVC, and trichloroethylene nephrotoxicity. They also suggest a role for hepatic metabolism in the mechanism of NA-DCVC nephrotoxicity. Copyright © 2012 Elsevier Inc. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dargent, B.; Couraud, F.
1990-08-01
To address the issue of whether regulatory feedback exists between the electrical activity of a neuron and ion-channel density, the authors investigated the effect of Na{sup +}-channel activators (scorpion {alpha} toxin, batrachotoxin, and veratridine) on the density of Na{sup +} channels in fetal rat brain neurons in vitro. A partial but rapid (t{sub 1/2}, 15 min) disappearance of surface Na{sup +} channels was observed as measured by a decrease in the specific binding of ({sup 3}H)saxitoxin and {sup 125}I-labeled scorpion {beta} toxin and a decrease in specific {sup 22}Na{sup +} uptake. Moreover, the increase in the number of Na{sup +}more » channels that normally occurs during neuronal maturation in vitro was inhibited by chronic channel activator treatment. The induced disappearance of Na{sup +} channels was abolished by tetrodotoxin, was found to be dependent on the external Na{sup +} concentration, and was prevented when either choline (a nonpermeant ion) or Li{sup +} (a permeant ion) was substituted for Na{sup +}. Amphotericin B, a Na{sup +} ionophore, and monensin were able to mimick the effect of Na{sup +}-channel activators, while a KCl depolarization failed to do this. This feedback regulation seems to be a neuronal property since Na{sup +}-channel density in cultured astrocytes was not affected by channel activator treatment or by amphotericin B. The present evidence suggests that an increase in intracellular Na{sup +} concentration, whether elicited by Na{sup +}-channel activators or mediated by a Na{sup +} ionophore, can induce a decrease in surface Na{sup +} channels and therefore is involved in down-regulation of Na{sup +}-channel density in fetal rat brain neurons in vitro.« less
Mushtaq, M. M. H.; Pasha, T. N.; Saima; Akram, M.; Mushtaq, T.; Parvin, R.; Farooq, U.; Mehmood, S.; Iqbal, K. J.; Hwangbo, J.
2013-01-01
A basal diet (0.8 g/kg dNa) was formulated in which each of the two sources (NaHCO3 and Na2SO4) were supplemented in such a way to attain four levels (1.7, 2.6, 3.5, and 4.4 g/kg) of total dNa, respectively, under 4×2 factorial arrangement. Eight dietary treatments were replicated four times, with 40 birds in each replicate (n = 1,280). The diets supplemented with Na2SO4 to attain higher levels of dNa showed highest BW gain and feed intake (FI) during d 1 to 10 (interaction effects) while 2.6 g/kg dNa exhibited improved BW gain and gain:feed (FG) during d 11 to 20. Linear rise in daily water intake (DWI) was associated with diets containing increasing dNa during d 1 to 42 (p≤0.036). During the first 10 d, DWI:FI was found highest in NaHCO3 diets while Na2SO4 diets showed highest DWI:FI during last 10 d of the experiment (p≤0.036). Increasing dNa and changing Na2SO4 with NaHCO3 salt increased pH and resulted in poor growth performance. Dressing weight (p≤0.001) and abdominal fat (p≤0.001; quadratic effect) were reduced, whereas breast (p≤0.001) and thigh (p<0.001) weights were aggravated with increasing dNa (linear effects). Present findings suggested higher levels of dNa from Na2SO4 as the supplemental salt in broiler diets would produce better growth performance, especially in first ten days of life, and improve carcass and body organ characteristics. PMID:25049765
A computational study of Na behavior on graphene
NASA Astrophysics Data System (ADS)
Malyi, Oleksandr I.; Sopiha, Kostiantyn; Kulish, Vadym V.; Tan, Teck L.; Manzhos, Sergei; Persson, Clas
2015-04-01
We present the first ab initio and molecular dynamics study of Na adsorption and diffusion on ideal graphene that considers Na-Na interaction and dispersion forces. From density functional theory (DFT) calculations using the generalized gradient approximation (GGA), the binding energy (vs. the vacuum reference state) of -0.75 eV is higher than the cohesive energy of Na metal (E
How far can sodium substitute for potassium in red beet?
NASA Technical Reports Server (NTRS)
Subbarao, G. V.; Wheeler, R. M.; Stutte, G. W.; Levine, L. H.; Sager, J. C. (Principal Investigator)
1999-01-01
Sodium (Na) movement between plants and humans is one of the more critical aspects of bioregenerative systems of life support, which NASA is studying for the establishment of long-term bases on the Lunar or Martian surface. This study was conducted to determine the extent to which Na can replace potassium (K) in red beet (Beta vulgaris L. ssp vulgaris) without adversely affecting metabolic functions such as water relations, photosynthetic rates, and thus growth. Two cultivars, Ruby Queen and Klein Bol, were grown for 42 days at 1200 micromoles mol-1 CO2 in a growth chamber using a re-circulating nutrient film technique with 0%, 75%, 95%, and 98% Na substitution for K in a modified half-strength Hoagland solution. Total biomass of Ruby Queen was greatest at 95% Na substitution and equal at 0% and 98% Na substitution. For Klein Bol, there was a 75% reduction in total biomass at 98% Na substitution. Nearly 95% of the total plant K was replaced with Na at 98% Na substitution in both cultivars. Potassium concentrations in leaves decreased from 120 g kg-1 dwt in 0% Na substitution to 3.5 g kg-1 dwt at 98% Na substitution. Leaf chlorophyll concentration, photosynthetic rate, and osmotic potential were not affected in either cultivar by Na substitution for K. Leaf glycinebetaine levels were doubled at 75% Na substitution in Klein Bol, but decreased at higher levels of Na substitution. For Ruby Queen, glycinebetaine levels in leaf increased with the first increase of Na levels and were maintained at the higher Na levels. These results indicate that in some cultivars of red beet, 95% of the normal tissue K can be replaced by Na without a reduction in growth.
Strong climate and tectonic control on plagioclase weathering in granitic terrain
Rasmussen, C.; Brantley, S.; Richter, D.D.B.; Blum, A.; Dixon, J.; White, A.F.
2011-01-01
Investigations to understand linkages among climate, erosion and weathering are central to quantifying landscape evolution. We approach these linkages through synthesis of regolith data for granitic terrain compiled with respect to climate, geochemistry, and denudation rates for low sloping upland profiles. Focusing on Na as a proxy for plagioclase weathering, we quantified regolith Na depletion, Na mass loss, and the relative partitioning of denudation to physical and chemical contributions. The depth and magnitude of regolith Na depletion increased continuously with increasing water availability, except for locations with mean annual temperature <5??C that exhibited little Na depletion, and locations with physical erosion rates <20gm-2yr-1 that exhibited deep and complete regolith Na depletion. Surface Na depletion also tended to decrease with increasing physical erosion. Depth-integrated Na mass loss and regolith depth were both three orders of magnitude greater in the fully depleted, low erosion rate sites relative to other locations. These locations exhibited strong erosion-limitation of Na chemical weathering rates based on correlation of Na chemical weathering rate to total Na denudation. Sodium weathering rates in cool locations with positive annual water balance were strongly correlated to total Na denudation and precipitation, and exhibited an average apparent activation energy (Ea) of 69kJmol-1 Na. The remaining water-limited locations exhibited kinetic limitation of Na weathering rates with an Ea of 136kJmol-1 Na, roughly equivalent to the sum of laboratory measures of Ea and dissolution reaction enthalpy for albite. Water availability is suggested as the dominant factor limiting rate kinetics in the water-limited systems. Together, these data demonstrate marked transitions and nonlinearity in how climate and tectonics correlate to plagioclase chemical weathering and Na mass loss. ?? 2010 Elsevier B.V.
Wu, H; Zhang, Z X; Zhao, H P; Wu, D C; Wu, B L; Cong, R
2004-12-01
Sodium fluoride-loaded gelatin microspheres (NaF-GMS) were prepared using double-phase emulsified condensation polymerization. The average diameter of microspheres was (11.33+/-5.56) microm. The drug content and encapsulation efficiency were 8.80% and 76.73%, respectively. The fluoride releasing profiles of NaF-GMS in physiological saline and artificial saliva (pH 4.5, pH 6.8) showed that NaF-GMS had a sustained-release property and fluoride release rate was increased in pH 4.5 artificial saliva. Experiments conducted in rabbits' oral cavity using NaF-GMS and NaF solution as control revealed NaF-GMS could maintain oral fluoride retention longer than NaF solution. Cariostatic abilities of NaF-GMS including demineralization prohibition in vitro, fluoride deposition in artificial dental plaque and the ability of targeting to cariogenic bacteria were investigated in artificial dental plaque. The results indicated NaF-GMS with lower fluoride concentrations could achieve equivalent cariostatic effect to the concentrated NaF solution, at the same time, could prolong fluoride retention in dental plaque. Microscopic observation showed that NaF-GMS carrying fusion protein of glucan-binding domain could adhere more bacteria than NaF-GMS and this might indicate the possibility of targeting to cariogenic bacteria when NaF-GMS were properly modified.
Reactions occurring during the sulfation of sodium chloride deposited on alumina substrates
NASA Technical Reports Server (NTRS)
Wu, C. S.; Birks, N.
1986-01-01
The reaction between solid NaCl and air containing 1 pct SO2 has been studied between 500 and 700 C. The reaction product, Na2SO4, forms not only on the surface of the NaCl but also on surrounding areas of the substrate due to the volatility of the NaCl at these temperatures. At the higher temperatures, the vapor pressure of NaCl is so high that the majority of the reaction product is distributed on the substrate. Above 625 C, the reaction product is a liquid solution of NaCl and Na2SO4 that exists only so long as NaCl is supplied from the original crystal source. Eventually, the liquid solidifies by constitutional solidification as the NaCl is converted to Na2SO4. While it exists, the liquid NaCl-Na2SO4 solution is shown to be highly corrosive to Al2O3 and, on a scale of Al2O3 growing on alloy HOS 875, particularly attacks the grain boundaries of the scale at preferred sites where chromium and iron oxides and sulfides rapidly develop. This is proposed as one mechanism by which NaCl deposition contributes to the initiation of low temperature hot corrosion.
2015-01-01
medics’ aid bags? 8% 92% N/A TCCC Pain Management Are you using TCCC guidelines pain medications?4 42% 12% 46% Fentanyl 69% 31% N/A Ketamine 50% 50% N...A Wound (Combat) Pill Pack 4% 96% N/A What pain medication do your medics carry? Morphine5 92% 8% N/A Fentanyl 35% 65% N/A Ketamine 12% 88% N/A TCCC
Logistics and the Fight -- Lessons from Napoleon
2011-04-07
Napoleon N/A Sb. GRANT NUMBER N/A Sc. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR( S ) 5d. PROJECT NUMBER LCDR Sean W. Toole, SC, USN N/A Se. TASK NUMBER N...A Sf. WORK UNIT NUMBER N/A 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION USMC Command and Staff College REPORT...NUMBER Marine Corps University N/A 2076 South Street Quantico, VA 22134-5068 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR
Applicability of Tenets of Operational Art in Low Intensity Conflict Operations (LICO) in India
2013-04-04
Major, Indian Army N/A N/A N/A USMC Command and Staff College Marine Corps University 2076 South Street Quantico, VA 22134-5068 N/A N/A N/A N/A...Approved for public release; distribution is unlimited N/A The identification and application of the tenets of operational art in LICO in the Indian ...and the security forces in particular. A thorough and deep understanding of the tenets of operational art as applicable to LICO in the Indian context
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yohannan, Jinu P.; Vidyasagar, Kanamaluru, E-mail: kvsagar@iitm.ac.in
Seven new non-centrosymmetric Na{sub 2}M{sub 2}M’S{sub 6} sulfides, namely, Na{sub 2}Sn{sub 2}ZnS{sub 6}(1){sub ,} Na{sub 2}Ga{sub 2}GeS{sub 6}(2), Na{sub 2}Ga{sub 2}SnS{sub 6}(3-α), Na{sub 2}Ga{sub 2}SnS{sub 6}(3-β){sub ,} Na{sub 2}Ge{sub 2}ZnS{sub 6}(4){sub ,} Na{sub 2}Ge{sub 2}CdS{sub 6}(5){sub ,} Na{sub 2}In{sub 2}SiS{sub 6}(6) and Na{sub 2}In{sub 2}GeS{sub 6}(7), were synthesized by high temperature solid state reactions and structurally characterized by single crystal X-ray diffraction. They crystallize in non-centrosymmetric Fdd2 and Cc space groups and their three-dimensional [M{sub 2}M′S{sub 6}]{sup 2-}framework structures consist of MS{sub 4} and M′S{sub 4} tetrahedra corner-connected to one another in either orderly or disordered fashion. Sodium ions residemore » in the tunnels of the anionic framework. Compounds 1, 2 and 3-α have the structure of known Li{sub 2}Ga{sub 2}GeS{sub 6}, whereas compounds 6 and 7 are isostructural with known Li{sub 2}In{sub 2}GeS{sub 6} compound. Isostructural compounds 4 and 5 represent a new structural variant. Compounds 3-α and its new monoclinic structural variant 3-β have disordered structural framework. All of them are wide band gap semiconductors. Na{sub 2}Ga{sub 2}GeS{sub 6}(2), Na{sub 2}Ga{sub 2}SnS{sub 6}(3), Na{sub 2}Ge{sub 2}ZnS{sub 6}(4) and Na{sub 2}In{sub 2}GeS{sub 6}(7) compounds are found to be second-harmonic generation (SHG) active. Compounds 1, 2 and 3-α melt congruently. - Graphical abstract: Na{sub 2}Ga{sub 2}GeS{sub 6}, Na{sub 2}Ga{sub 2}SnS{sub 6}, Na{sub 2}Ge{sub 2}ZnS{sub 6}, Na{sub 2}In{sub 2}GeS{sub 6}, Na{sub 2}Sn{sub 2}ZnS{sub 6}, Na{sub 2}Ge{sub 2}CdS{sub 6} and Na{sub 2}In{sub 2}SiS{sub 6} have non-centrosymmetric structures and the first four compounds are SHG active. Display Omitted - Highlights: • Seven new Na{sub 2}M{sub 2}M′S{sub 6} compounds with non-centrosymmetric structures were synthesized. • They are wide band gap semiconductors. • Na{sub 2}Ga{sub 2}GeS{sub 6}, Na{sub 2}Ga{sub 2}SnS{sub 6}, Na{sub 2}Ge{sub 2}ZnS{sub 6} and Na{sub 2}In{sub 2}GeS{sub 6} are SHG active.« less
Na+/H+ Exchange Activity in the Plasma Membrane of Arabidopsis1
Qiu, Quan-Sheng; Barkla, Bronwyn J.; Vera-Estrella, Rosario; Zhu, Jian-Kang; Schumaker, Karen S.
2003-01-01
In plants, Na+/H+ exchangers in the plasma membrane are critical for growth in high levels of salt, removing toxic Na+ from the cytoplasm by transport out of the cell. The molecular identity of a plasma membrane Na+/H+ exchanger in Arabidopsis (SOS1) has recently been determined. In this study, immunological analysis provided evidence that SOS1 localizes to the plasma membrane of leaves and roots. To characterize the transport activity of this protein, purified plasma membrane vesicles were isolated from leaves of Arabidopsis. Na+/H+ exchange activity, monitored as the ability of Na to dissipate an established pH gradient, was absent in plants grown without salt. However, exchange activity was induced when plants were grown in 250 mm NaCl and increased with prolonged salt exposure up to 8 d. H+-coupled exchange was specific for Na, because chloride salts of other monovalent cations did not dissipate the pH gradient. Na+/H+ exchange activity was dependent on Na (substrate) concentration, and kinetic analysis indicated that the affinity (apparent Km) of the transporter for Na+ is 22.8 mm. Data from two experimental approaches supports electroneutral exchange (one Na+ exchanged for one proton): (a) no change in membrane potential was measured during the exchange reaction, and (b) Na+/H+ exchange was unaffected by the presence or absence of a membrane potential. Results from this research provide a framework for future studies into the regulation of the plant plasma membrane Na+/H+ exchanger and its relative contribution to the maintenance of cellular Na+ homeostasis during plant growth in salt. PMID:12805632
Na+/H+ exchange activity in the plasma membrane of Arabidopsis.
Qiu, Quan-Sheng; Barkla, Bronwyn J; Vera-Estrella, Rosario; Zhu, Jian-Kang; Schumaker, Karen S
2003-06-01
In plants, Na+/H+ exchangers in the plasma membrane are critical for growth in high levels of salt, removing toxic Na+ from the cytoplasm by transport out of the cell. The molecular identity of a plasma membrane Na+/H+ exchanger in Arabidopsis (SOS1) has recently been determined. In this study, immunological analysis provided evidence that SOS1 localizes to the plasma membrane of leaves and roots. To characterize the transport activity of this protein, purified plasma membrane vesicles were isolated from leaves of Arabidopsis. Na+/H+ exchange activity, monitored as the ability of Na to dissipate an established pH gradient, was absent in plants grown without salt. However, exchange activity was induced when plants were grown in 250 mm NaCl and increased with prolonged salt exposure up to 8 d. H+-coupled exchange was specific for Na, because chloride salts of other monovalent cations did not dissipate the pH gradient. Na+/H+ exchange activity was dependent on Na (substrate) concentration, and kinetic analysis indicated that the affinity (apparent Km) of the transporter for Na+ is 22.8 mm. Data from two experimental approaches supports electroneutral exchange (one Na+ exchanged for one proton): (a) no change in membrane potential was measured during the exchange reaction, and (b) Na+/H+ exchange was unaffected by the presence or absence of a membrane potential. Results from this research provide a framework for future studies into the regulation of the plant plasma membrane Na+/H+ exchanger and its relative contribution to the maintenance of cellular Na+ homeostasis during plant growth in salt.
Nutritional Relationships in Schistosomiasis.
1978-07-01
to presence of ou~bain, phlorizin, phloretin . 1lexose mediated accumulation is Na coupled. Accession For NTIS GREA&I DDC TAB Unannounced...mediat,!d system is apparently Na + dependent and sensitive to presence of ouabain, phlorizin, phloretin . Hexose mediated accumulation is Na+ coupled. i...decreased Na+, ouabain, phiorizin phloretin and other sugars. Studies with Na22 suggest that the accumulation of 2-deoxyglucose and Na+ were coupled
Acidosis Differentially Modulates Inactivation in NaV1.2, NaV1.4, and NaV1.5 Channels
Vilin, Yury Y.; Peters, Colin H.; Ruben, Peter C.
2012-01-01
NaV channels play a crucial role in neuronal and muscle excitability. Using whole-cell recordings we studied effects of low extracellular pH on the biophysical properties of NaV1.2, NaV1.4, and NaV1.5, expressed in cultured mammalian cells. Low pH produced different effects on different channel subtypes. Whereas NaV1.4 exhibited very low sensitivity to acidosis, primarily limited to partial block of macroscopic currents, the effects of low pH on gating in NaV1.2 and NaV1.5 were profound. In NaV1.2 low pH reduced apparent valence of steady-state fast inactivation, shifted the τ(V) to depolarizing potentials and decreased channels availability during onset to slow and use-dependent inactivation (UDI). In contrast, low pH delayed open-state inactivation in NaV1.5, right-shifted the voltage-dependence of window current, and increased channel availability during onset to slow and UDI. These results suggest that protons affect channel availability in an isoform-specific manner. A computer model incorporating these results demonstrates their effects on membrane excitability. PMID:22701426
NASA Astrophysics Data System (ADS)
Thangaraju, Dheivasigamani; Santhana, Vedi; Matsuda, Satoshi; Hayakawa, Yasuhiro
2018-05-01
Hexagonal NaYF4:Yb:Er:Tm@NaGdF4 core-shell nanocrystals were synthesized using a seed mediated hot injection method, and monodispersed Fe3O4 (4 nm) nanoparticles were prepared from iron(II) actylacetonate by a precursor thermal decomposition method. Structural and morphology verified NaYF4:Yb:Er:Tm@NaGdF4 and Fe3O4 nanoparticles were utilized for the preparation of NaYF4:Yb:Er:Tm@NaGdF4/Fe3O4@SiO2 nanocomposite using a micro-emulsion method. Existence of Fe3O4 in NaYF4:Yb:Er:Tm@NaGdF4 in SiO2 nano-spheres were confirmed with transmission electron microscopy. Luminescence measurement revealed that NaYF4:Yb:Er:Tm@NaGdF4 exhibited strong emissions at green and red regions, in addition to a weak blue emission also observed under 980 nm excitation. Up-conversion emission of the nanoparticle-embedded silica nanocomposite showed that the up-conversion emission was not affected by Fe3O4 nanoparticles.
Structure-based assessment of disease-related mutations in human voltage-gated sodium channels.
Huang, Weiyun; Liu, Minhao; Yan, S Frank; Yan, Nieng
2017-06-01
Voltage-gated sodium (Na v ) channels are essential for the rapid upstroke of action potentials and the propagation of electrical signals in nerves and muscles. Defects of Na v channels are associated with a variety of channelopathies. More than 1000 disease-related mutations have been identified in Na v channels, with Na v 1.1 and Na v 1.5 each harboring more than 400 mutations. Na v channels represent major targets for a wide array of neurotoxins and drugs. Atomic structures of Na v channels are required to understand their function and disease mechanisms. The recently determined atomic structure of the rabbit voltage-gated calcium (Ca v ) channel Ca v 1.1 provides a template for homology-based structural modeling of the evolutionarily related Na v channels. In this Resource article, we summarized all the reported disease-related mutations in human Na v channels, generated a homologous model of human Na v 1.7, and structurally mapped disease-associated mutations. Before the determination of structures of human Na v channels, the analysis presented here serves as the base framework for mechanistic investigation of Na v channelopathies and for potential structure-based drug discovery.
Growth of binary organic NLO crystals: m.NA-p.NA and m.NA-CNA system
NASA Technical Reports Server (NTRS)
Singh, N. B.; Henningsen, T.; Hopkins, R. H.; Mazelsky, R.
1993-01-01
Experiments were carried out to grow 3.Nitroaniline (m.NA) crystals doped with 4.Nitroaniline (p.NA) and 2.chloro 4.Nitroaniline (CNA). The measured undercooling for m.NA, p.NA, and CNA were 0.21 tm K, 0.23 tm K, and 0.35 tm K respectively, where tm represents the melting temperature of the pure component. Because of the crystals' large heat of fusion and large undercooling, it was not possible to grow good quality crystals with low thermal gradients. In the conventional two-zone Bridgman furnace we had to raise the temperature of the hot zone above the decomposition temperature of CNA, p.NA, and m.NA to achieve the desired thermal gradient. To avoid decomposition, we used an unconventional Bridgman furnace. Two immiscible liquids, silicone oil and ethylene glycol, were used to build a special two-zone Bridgman furnace. A temperature gradient of 18 K/cm was achieved without exceeding the decomposition temperature of the crystal. The binary crystals, m.NA-p.NA and m.NA-CNA, were grown in centimeter size in this furnace. X-ray and optical characterization showed good optical quality.
A Quaternary Sodium Superionic Conductor - Na 10.8Sn 1.9PS 11.8
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yu, Zhaoxin; Shang, Shun -Li; Gao, Yue
Sulfide-based Na-ion conductors are promising candidates as solid-state electrolytes (SSEs) for fabrication of solid-state Na-ion batteries (NIBs) because of their high ionic conductivities and low grain boundary resistance. Currently, most of the sulfide-based Na-ion conductors with high conductivities are focused on Na 3PS 4 phases and its derivatives. It is desirable to develop Na-ion conductors with new composition and crystal structure to achieve superior ionic conductivities. Here we report a new quaternary Na-ion conductor, Na 10.8Sn 1.9PS 11.8, exhibiting a high ionic conductivity of 0.67 mS cm –1 at 25 °C. This high ionic conductivity originates from the presence ofmore » a large number of intrinsic Na-vacancies and three-dimensional Na-ion conduction pathways, which has been confirmed by single-crystal X-ray diffraction and first-principles calculations. In conclusion, the Na 10.8Sn 1.9PS 11.8 phase is further evaluated as an electrolyte in a Na-Sn alloy/TiS 2 battery, demonstrating its potential application in all-solid-state NIBs.« less
A Quaternary Sodium Superionic Conductor - Na 10.8Sn 1.9PS 11.8
Yu, Zhaoxin; Shang, Shun -Li; Gao, Yue; ...
2018-01-31
Sulfide-based Na-ion conductors are promising candidates as solid-state electrolytes (SSEs) for fabrication of solid-state Na-ion batteries (NIBs) because of their high ionic conductivities and low grain boundary resistance. Currently, most of the sulfide-based Na-ion conductors with high conductivities are focused on Na 3PS 4 phases and its derivatives. It is desirable to develop Na-ion conductors with new composition and crystal structure to achieve superior ionic conductivities. Here we report a new quaternary Na-ion conductor, Na 10.8Sn 1.9PS 11.8, exhibiting a high ionic conductivity of 0.67 mS cm –1 at 25 °C. This high ionic conductivity originates from the presence ofmore » a large number of intrinsic Na-vacancies and three-dimensional Na-ion conduction pathways, which has been confirmed by single-crystal X-ray diffraction and first-principles calculations. In conclusion, the Na 10.8Sn 1.9PS 11.8 phase is further evaluated as an electrolyte in a Na-Sn alloy/TiS 2 battery, demonstrating its potential application in all-solid-state NIBs.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ogawa, E.; Suzuki, S.; Fukuda, R.
Pharmacological means to accelerate the elimination of Cs-137 introduced into the living organism are studied. Male dd mice and male Wistar rats are individually housed in metal metabolism cages, and provided with commercial solid diet and water. Radioactivity is determined in urine, and feces for 24 hours and 4 days after subcutaneous injection of a tracer dose of Cs/sup 137/Cl, and in various organs after sacrifices at the ends of these periods. Effects of various chemicals on these results are compared. Twenty five chemicals were investigated. They include inorganic Na salts such as Na bicarbonate, Na carbonate, Na suliate, Namore » thiosulfate, primary and secondary Na phosphates, and organic Na salts such as Na lactate, lactated Ringer, Na acetate, Na glucuronate, Na salt of thioctic acid, ATP Na, and Na pentobarbiturate. Na bicarbonate, Na phosphates, Na sulfate, and Na thiosulfate are found as eifective, especially Na bicarbonate, K bicarbonate shows scarcely any effect, nor do other K salts. It is therefore assumed that Cs will exchange with Na ion in the tubular cells. LiCl is found to accelerate the excretion of Cs-137 from mice and rats. This result is of interest with respect to the periodic law, since it is known that for the elimination of Sr-90, Ca salts are ineffective or slightly effective, whereas Mg salts are effective. Of the diuretics, chlorothiazide, which is considered to increase the excretion of K, does nor increase the elimination of Cs-137 in any dose. This result is different from that of Diamox, a diuretic of the same nature. Cardiac glycosides and xanthine derivatives are effective. Out of digitalis preparations, Digitamin (Shionogi), Digilanogen C (Fujisawa), Digosin (Chugai) are effective. Digitoxin and strospeside are ineffective, and after their application, retention of Cs-137 is observed in the heart muscle. G- strophanthin is ineffective in a smaller dose, but increases the elimination of Cs-137 in a larger dose. Caffeine and sodium benzoate are also effective, but theophylline and theobromine are not so effective. Out of osmotic diuretics, Na ferrocyanate alone increases fecal excretion of Cs-137, and decreases the retention in the body. NaI and KI have scarcely any effect. Phosphomolybdic acid inhibits the elimination of Cs-137 and increases its retention. The above mentioned effective chemicals are also investigated for effects on the elimination of Sr-90. (JAIF)« less
de Souza, Rodrigo C; Colombo, Ana Paula V
2006-07-01
Polymorphisms in FcgammaR have been associated with different forms of periodontitis. This study determined the frequency of FcgammaRIIa and FcgammaRIIIb alleles/genotypes in patients with generalized aggressive periodontitis (GAgP). Thirty-one GAgP and 49 periodontally healthy Brazilian subjects participated in the study. Full-mouth periodontal examinations were carried out, and mouthwash samples were collected for human DNA isolation. FcgammaR genotyping was performed by polymerase chain reaction and hybridization with allele-specific oligonucleotide probes. Significant differences between groups were sought by Mann-Whitney, chi2, and Fisher exact tests and configural frequency analysis. FcgammaRIIa-H131 (53.8%) and FcgammaRIIIb-NA1 (75%) were the most prevalent alleles in this sample population. A significant overrepresentation of FcgammaRIIIb-NA2 was observed in the GAgP group, whereas FcgammaRIIIb-NA1 was detected more often in healthy individuals (odds ratio, 32.5; 95% confidence interval [CI], 10.6 to 99.8; P<0.001). No significant differences in the distribution of the FcgammaRIIa genotypes were observed between the groups. The prevalence of FcgammaRIIIb-NA2/NA2 was higher in GAgP patients, whereas FcgammaRIIIb-NA1/NA1 was predominant in the healthy group (chi2=45.1; P<0.001). The combination of the genotypes FcgammaRIIIb-NA2/NA2 plus FcgammaRIIa-H/H131 was observed more frequently in GAgP subjects than expected from marginal frequencies (chi2=12.5; P<0.001). The data suggest that the FcgammaRIIIb-NA2 allele and/or FcgammaRIIIb-NA2/NA2 genotype and the composite genotype FcgammaRIIIb-NA2/NA2 plus FcgammaRIIa-H/H131 may be associated with GAgP, whereas FcgammaRIIIb-NA1 and/or FcgammaRIIIb-NA1/NA1 may be related to periodontal health in this sample of the Brazilian population.
2016-01-01
Operando pair distribution function (PDF) analysis and ex situ 23Na magic-angle spinning solid-state nuclear magnetic resonance (MAS ssNMR) spectroscopy are used to gain insight into the alloying mechanism of high-capacity antimony anodes for sodium-ion batteries. Subtraction of the PDF of crystalline NaxSb phases from the total PDF, an approach constrained by chemical phase information gained from 23Na ssNMR in reference to relevant model compounds, identifies two previously uncharacterized intermediate species formed electrochemically; a-Na3–xSb (x ≈ 0.4–0.5), a structure locally similar to crystalline Na3Sb (c-Na3Sb) but with significant numbers of sodium vacancies and a limited correlation length, and a-Na1.7Sb, a highly amorphous structure featuring some Sb–Sb bonding. The first sodiation breaks down the crystalline antimony to form first a-Na3–xSb and, finally, crystalline Na3Sb. Desodiation results in the formation of an electrode formed of a composite of crystalline and amorphous antimony networks. We link the different reactivity of these networks to a series of sequential sodiation reactions manifesting as a cascade of processes observed in the electrochemical profile of subsequent cycles. The amorphous network reacts at higher voltages reforming a-Na1.7Sb, then a-Na3–xSb, whereas lower potentials are required for the sodiation of crystalline antimony, which reacts to form a-Na3–xSb without the formation of a-Na1.7Sb. a-Na3–xSb is converted to crystalline Na3Sb at the end of the second discharge. We find no evidence of formation of NaSb. Variable temperature 23Na NMR experiments reveal significant sodium mobility within c-Na3Sb; this is a possible contributing factor to the excellent rate performance of Sb anodes. PMID:26824406
DOE Office of Scientific and Technical Information (OSTI.GOV)
Allan, Phoebe K.; Griffin, John M.; Darwiche, Ali
Operando pair distribution function (PDF) analysis and ex situ Na-23 magic-angle spinning solid-state nuclear magnetic resonance (MAS ssNMR) spectroscopy are used to gain insight into the alloying mechanism of high-capacity antimony anodes for sodium-ion batteries. Subtraction of the PDF of crystalline NaxSb phases from the total PDF, an approach constrained by chemical phase information gained from Na-23 ssNMR in reference to relevant model compounds, identifies two previously uncharacterized intermediate species formed electro-chemically; a-Na3-xSb (x approximate to 0.4-0.5), a structure locally similar to crystalline Na3Sb (c-Na3Sb) but with significant numbers of sodium vacancies and a limited correlation length, and a-Na1.7Sb, amore » highly amorphous structure featuring some Sb-Sb bonding. The first sodiation breaks down the crystalline antimony to form first a-Na3-xSb and, finally, crystalline Na3Sb. Desodiation results in the formation of an electrode formed of a composite of crystalline and amorphous antimony networks. We link the different reactivity of these networks to a series of sequential sodiation reactions manifesting as a cascade of processes observed in the electrochemical profile of subsequent cycles. The amorphofis network reacts at higher voltages reforming a-Na1.7Sb, then a-Na3-xSb, whereas lower potentials are required for the sodiation of crystalline antimony, which reacts to form a-Na3-xSb without the formation of a-Na3-xSb. a-Na3-xSb is converted to crystalline Na3Sb at the end of the second discharge. We find no evidence of formation of NaSb. Variable temperature Na-23 NMR experiments reveal significant sodium mobility within c-Na3Sb; this is a possible contributing factor to the excellent rate performance of Sb anodes.« less
Kinetic contribution to extracellular Na+/K+ selectivity in the Na+/K+ pump.
Vleeskens, Elizabeth; Clarke, Ronald J
2018-05-01
The sodium potassium pump (Na + ,K + -ATPase) shows a high selectivity for K + over Na + binding from the extracellular medium. To understand the K + selectivity in the presence of a high concentration of competing Na + ions requires consideration of more than just ion binding affinities. Here, equilibrium-based calculations of the extracellular occupation of the Na + ,K + -ATPase transport sites by Na + and K + are compared to fluxes through Na + and K + transport pathways. The results show that, under physiological conditions, there is a 332-fold selectivity for pumping of K + from the extracellular medium into the cytoplasm relative to Na + , whereas equilibrium calculations alone predict only a 7.5-fold selectivity for K + . Thus, kinetic effects make a major contribution to the determination of extracellular K + selectivity.
Indigenous Advanced Fighter Aircraft in Israel: Considerations for Decision-Making.
1981-12-01
13 ISO 11,i 30 2 0.2 3.3 1975 924 1029 555 6219 3036 25 255 16.6 33 9 0.4 4.1 1976 969 1022 6311 6676 3164 34 405 IS3 32.3 0.5 6.1 1971 1047... Iso 49 NA 47.1 14 4 NA 30.6 NA 4138 1179 1975 3.5 190 54 NA 54.3 15.4 NA 23.4 NA 4127 1308 1976 3 5 190 57 NA 54.3 16.3 NA 30.0 NA 4087 1337 1977 3.6...357 17400 28266 15200 24692 0. I 1 4 1970 10 15 200 308 19100 29503 18100 27958 0.0 1.1 197 t0 14 ISO 220 21300 31305 20800 30570 0 0 0.7 1972 20
Chen, Desheng; Zhao, Longsheng; Liu, Yahui; Qi, Tao; Wang, Jianchong; Wang, Lina
2013-01-15
A novel process for recovering iron, titanium, and vanadium from titanomagnetite concentrates has been developed. In the present paper, the treatment of rich titanium-vanadium slag by NaOH molten salt roasting and water leaching processes is investigated. In the NaOH molten salt roasting process, the metallic iron is oxidized into ferriferous oxide, MgTi(2)O(5) is converted to NaCl-type structure of Na(2)TiO(3), and M(3)O(5) (M=Ti, Mg, Fe) is converted to α-NaFeO(2)-type structure of NaMO(2), respectively. Roasting temperature and NaOH-slag mass ratio played a considerable role in the conversion of titanium in the rich titanium-vanadium slag during the NaOH molten salt roasting process. Roasting at 500 °C for 60 min and a 1:1 NaOH-slag mass ratio produces 96.3% titanium conversion. In the water leaching process, the Na(+) was exchanged with H(+), Na(2)TiO(3) is converted to undefined structure of H(2)TiO(3), and NaMO(2) is converted to α-NaFeO(2)-type structure of HMO(2). Under the optimal conditions, 87.3% of the sodium, 42.3% of the silicon, 43.2% of the aluminum, 22.8% of the manganese, and 96.6% of the vanadium are leached out. Crown Copyright © 2012. Published by Elsevier B.V. All rights reserved.
Møller, Inge S.; Gilliham, Matthew; Jha, Deepa; Mayo, Gwenda M.; Roy, Stuart J.; Coates, Juliet C.; Haseloff, Jim; Tester, Mark
2009-01-01
Soil salinity affects large areas of cultivated land, causing significant reductions in crop yield globally. The Na+ toxicity of many crop plants is correlated with overaccumulation of Na+ in the shoot. We have previously suggested that the engineering of Na+ exclusion from the shoot could be achieved through an alteration of plasma membrane Na+ transport processes in the root, if these alterations were cell type specific. Here, it is shown that expression of the Na+ transporter HKT1;1 in the mature root stele of Arabidopsis thaliana decreases Na+ accumulation in the shoot by 37 to 64%. The expression of HKT1;1 specifically in the mature root stele is achieved using an enhancer trap expression system for specific and strong overexpression. The effect in the shoot is caused by the increased influx, mediated by HKT1;1, of Na+ into stelar root cells, which is demonstrated in planta and leads to a reduction of root-to-shoot transfer of Na+. Plants with reduced shoot Na+ also have increased salinity tolerance. By contrast, plants constitutively expressing HKT1;1 driven by the cauliflower mosaic virus 35S promoter accumulated high shoot Na+ and grew poorly. Our results demonstrate that the modification of a specific Na+ transport process in specific cell types can reduce shoot Na+ accumulation, an important component of salinity tolerance of many higher plants. PMID:19584143
Phase behavior, morphology, and polymorphism of surfactant systems
NASA Astrophysics Data System (ADS)
Liang, Jingmei
Surfactants are amphiphilic molecules. They spontaneously form various microstructures in water to accommodate the hydrophilic-hydrophobic interactions. Soaps are the oldest kind of man-made surfactants that are commonly used as washing and cleaning agents. In spite of the long history of soap research, many aspects of soaps in nonaqueous solvents remain unclear. Unlike the aqueous soap systems, which have been studied extensively, investigations of nonaqueous, polar soap systems are rather limited. Motivated by the applications of nonaqueous, polar solvents in soap products, we investigated sodium stearate (NaSt)/water/propylene glycol (PG) systems. The effects of gradual substitution of PG for H 2O on the phase behavior, morphology and crystalline structure of NaSt systems were studied by a combination of characterization techniques. The techniques include direct visual observation, differential scanning calorimetry, wide-angle and small angle x-ray scattering, light and cryo-electron microscopy, and solid-state nuclear magnetic resonance. Anhydrous NaSt forms layered crystalline structures at 25°C. With increasing temperature, a distorted hexagonal phase and a hexagonal liquid crystalline phase form. Compared with aqueous soap systems, the regions of liquid crystalline phases in the phase diagrams are reduced as PG replaces or gradually substitutes for H2O. Fibrous and plate-like NaSt crystallites were investigated in the NaSt/PG/H 2O system containing 1-5 wt% NaSt. Despite of the morphological difference, NaSt fibers and platelets share the same layered crystalline structure at the molecular level. NaSt fibers consist of stacked thin ribbons of NaSt bilayers. NaSt platelets exhibit large basal planes {001} surrounded by other faster-growing lateral planes. Two lamellar crystalline structures, alpha-NaSt and beta-NaSt, which formed in the NaSt/PG/H2O system with 10 wt% NaSt, were characterized on the atomic, molecular and microscopic levels. In a PG concentration range of 60-95 wt% in mixtures of H2O and PG, beta-NaSt transforms to alpha-NaSt upon aging. Compared with beta-NaSt, the hydrocarbon chains in alpha-NaSt consist of a higher percentage of trans conformation, which is characteristically more orderly packed and more rigid. alpha-NaSt exhibits a larger bilayer thickness, and dissolves at a lower temperature in the PG/H 2O mixture. The fibrous crystallites of alpha-NaSt are more bundled and oriented compared to those of beta-NaSt.
Extremely Stable Sodium Metal Batteries Enabled by Localized High-Concentration Electrolytes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zheng, Jianming; Chen, Shuru; Zhao, Wengao
Sodium (Na) metal is a promising anode for Na ion batteries. However, the high reactivity of Na metal with electrolytes and the low Na metal cycling efficiency have limited its practical application in rechargeable Na metal batteries. High concentration electrolytes (HCE, ≥4 M) consisting of sodium bis(fluorosulfonyl)imide (NaFSI) and ether solvent could ensure the stable cycling of Na metal with high coulombic efficiency, but suffer from high viscosity, poor wetting ability, and high salt cost. Here, we report that the salt concentration could be significantly reduced (≤ 1.5 M) by diluting with a hydrofluoroether (HFE) as ‘inert’ diluent, which maintainsmore » the solvation structures of HCE, thereby forming a localized high concentration electrolyte (LHCE). A LHCE (2.1 M NaFSI/DME-BTFE (solvent molar ratio 1:2)) has been demonstrated to enable the dendrite-free Na deposition with high coulombic efficiency of > 99%, fast-charging (20C) and stable cycling (90.8% retention after 40,000 cycles) of Na||Na3V2(PO4)3 batteries.« less
NASA Astrophysics Data System (ADS)
Song, Hee Jo; Kim, Jae-Chan; Dar, Mushtaq Ahmad; Kim, Dong-Wan
2018-02-01
With the increasing demand for high energy density in energy-storage systems, a high-voltage cathode is essential in rechargeable Li-ion and Na-ion batteries. The operating voltage of a triclinic-polymorph Na2CoP2O7, also known as the rose form, is above 4.0 V (vs. Na/Na+), which is relatively high compared to that of other cathode materials. Thus, it can be employed as a potential high-voltage cathode material in Na-ion batteries. However, it is difficult to synthesize a pure rose phase because of its low phase stability, thus limiting its use in high-voltage applications. Herein, compositional-engineered, rose-phase Na2-2xCo1+xP2O7/C (x = 0, 0.1 and 0.2) nanopowder are prepared using a wet-chemical method. The Na2-2xCo1+xP2O7/C cathode shows high electrochemical reactivity with Na ions at 4.0 V, delivering high capacity and high energy density.
Mechanisms of Sodium Transport in Plants—Progresses and Challenges
Keisham, Monika; Mukherjee, Soumya; Bhatla, Satish C.
2018-01-01
Understanding the mechanisms of sodium (Na+) influx, effective compartmentalization, and efflux in higher plants is crucial to manipulate Na+ accumulation and assure the maintenance of low Na+ concentration in the cytosol and, hence, plant tolerance to salt stress. Na+ influx across the plasma membrane in the roots occur mainly via nonselective cation channels (NSCCs). Na+ is compartmentalized into vacuoles by Na+/H+ exchangers (NHXs). Na+ efflux from the plant roots is mediated by the activity of Na+/H+ antiporters catalyzed by the salt overly sensitive 1 (SOS1) protein. In animals, ouabain (OU)-sensitive Na+, K+-ATPase (a P-type ATPase) mediates sodium efflux. The evolution of P-type ATPases in higher plants does not exclude the possibility of sodium efflux mechanisms similar to the Na+, K+-ATPase-dependent mechanisms characteristic of animal cells. Using novel fluorescence imaging and spectrofluorometric methodologies, an OU-sensitive sodium efflux system has recently been reported to be physiologically active in roots. This review summarizes and analyzes the current knowledge on Na+ influx, compartmentalization, and efflux in higher plants in response to salt stress. PMID:29495332
C. Eyre; K. Hayden; M. Kozanitas; N. Grunwald; M. Garbelotto
2014-01-01
There are four recognized clonal lineages of the pathogen Phytophthora ramorum. The two major lineages present in North America are NA1 and NA2. With a few exceptions, NA1 is found in natural forest ecosystems and nurseries, and NA2 is generally restricted to nurseries. Isolates from the NA1 and NA2 lineages were used to infect rhododendron,...
SLC4A11 is an EIPA-sensitive Na+ permeable pHi regulator
Ogando, Diego G.; Jalimarada, Supriya S.; Zhang, Wenlin; Vithana, Eranga N.
2013-01-01
Slc4a11, a member of the solute linked cotransporter 4 family that is comprised predominantly of bicarbonate transporters, was described as an electrogenic 2Na+-B(OH)4− (borate) cotransporter and a Na+-2OH− cotransporter. The goal of the current study was to confirm and/or clarify the function of SLC4A11. In HEK293 cells transfected with SLC4A11 we tested if SLC4A11 is a: 1) Na+-HCO3− cotransporter, 2) Na+-OH−(H+) transporter, and/or 3) Na+-B(OH)4− cotransporter. CO2/HCO3− perfusion yielded no significant differences in rate or extent of pHi changes or Na+ flux in SLC4A11-transfected compared with control cells. Similarly, in CO2/HCO3−, acidification on removal of Na+ and alkalinization on Na+ add back were not significantly different between control and transfected indicating that SLC4A11 does not have Na+-HCO3− cotransport activity. In the absence of CO2/HCO3−, SLC4A11-transfected cells showed higher resting intracelllular Na+ concentration ([Na+]i; 25 vs. 17 mM), increased NH4+-induced acidification and increased acid recovery rate (160%) after an NH4 pulse. Na+ efflux and influx were faster (80%) following Na+ removal and add back, respectively, indicative of Na+-OH−(H+) transport by SLC4A11. The increased alkalinization recovery was confirmed in NHE-deficient PS120 cells demonstrating that SLC4A11 is a bonafide Na+-OH−(H+) transporter and not an activator of NHEs. SLC4A11-mediated H+ efflux is inhibited by 5-(N-ethyl-N-isopropyl) amiloride (EIPA; EC50: 0.1 μM). The presence of 10 mM borate did not alter dpHi/dt or ΔpH during a Na+-free pulse in SLC4A11-transfected cells. In summary our results show that SLC4A11 is not a bicarbonate or borate-linked transporter but has significant EIPA-sensitive Na+-OH−(H+) and NH4+ permeability. PMID:23864606
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nguyen Ngoc, Tam Dan; Son, Young-Ok; Lim, Shin-Saeng
2012-03-15
Sodium fluoride (NaF) is used as a source of fluoride ions in diverse applications. Fluoride salt is an effective prophylactic for dental caries and is an essential element required for bone health. However, fluoride is known to cause cytotoxicity in a concentration-dependent manner. Further, no information is available on the effects of NaF on mouse embryonic stem cells (mESCs). We investigated the mode of cell death induced by NaF and the mechanisms involved. NaF treatment greater than 1 mM reduced viability and DNA synthesis in mESCs and induced cell cycle arrest in the G{sub 2}/M phase. The addition of NaFmore » induced cell death mainly by apoptosis rather than necrosis. Catalase (CAT) treatment significantly inhibited the NaF-mediated cell death and also suppressed the NaF-mediated increase in phospho-c-Jun N-terminal kinase (p-JNK) levels. Pre-treatment with SP600125 or z-VAD-fmk significantly attenuated the NaF-mediated reduction in cell viability. In contrast, intracellular free calcium chelator, but not of sodium or calcium ion channel blockers, facilitated NaF-induced toxicity in the cells. A JNK specific inhibitor (SP600125) prevented the NaF-induced increase in growth arrest and the DNA damage-inducible protein 45α. Further, NaF-mediated loss of mitochondrial membrane potential was apparently inhibited by pifithrin-α or CAT inhibitor. These findings suggest that NaF affects viability of mESCs in a concentration-dependent manner, where more than 1 mM NaF causes apoptosis through hydroxyl radical-dependent and caspase- and JNK-mediated pathways. -- Highlights: ► The mode of NaF-induced cell death and the mechanisms involved were examined. ► NaF induced mainly apoptotic death of mouse embryonic stem cells (mESCs). ► NaF induced mitochondrial-mediated and caspase-dependent apoptosis. ► JNK- and p53-mediated pathways are involved in NaF-mediated apoptosis in the cells. ► ROS are the up-stream effector in NaF-mediated activation of JNK and p53 in mESCs.« less
Taste and acceptance of pyrophosphates by rats and mice.
McCaughey, Stuart A; Giza, Barbara K; Tordoff, Michael G
2007-06-01
The palatability and taste quality of pyrophosphates were evaluated in a series of behavioral and electrophysiological experiments. In two-bottle choice tests with water, rats strongly preferred some concentrations of Na3HP2O7 and Na4P2O7, moderately preferred some concentrations of K4P2O7 and Fe4(P2O7)3, and were indifferent to or avoided all concentrations of Ca2P2O7 and Na2H2P2O7. The contribution of sodium to the preference for sodium pyrophosphates was ascertained: 1) Rats with a choice between Na4P2O7 and NaCl preferred 1 mM Na4P2O7 to 4 mM NaCl but preferred 40 or 150 mM NaCl to 10 mM Na4P2O7, 2) blocking salt taste transduction by mixing Na4P2O7 with amiloride reduced preferences but did not eliminate them, and 3) three mouse strains (FVB/J, C57BL/6J, and CBA/J) known to differ in sodium preference had the same rank order of preferences for Na3HP2O7 and NaCl, but peak preferences were higher for Na3HP2O7 than for NaCl. The taste qualities of pyrophosphates were determined by measuring taste-evoked responses of neurons in the nucleus of the solitary tract of rats. Across-neuron patterns of activity for sodium pyrophosphates were similar to that of NaCl but the pattern of Na3HP2O7 plus amiloride was unique from those of sweet, salty, sour, bitter, and umami stimuli. Taken together, the results indicate that the high palatability of some concentrations of Na3HP2O7 and Na4P2O7 is due partially to their salty taste, but there must also be another cause, which may include a novel orosensory component distinct from the five major taste qualities.
FTIR spectra of the solid solutions (Na0.88K0.12)VO3, (Na0.5K0.5)VO3, and Na(V0.66P0.34)O3
NASA Astrophysics Data System (ADS)
de Waal, D.; Heyns, A. M.
1992-03-01
It is known that three different solid solutions, (Na0.88K0.12)VO3, (Na0.5K0.5)VO3 and Na(V0.66P0.34)O3, form in the (Na,K)(V,P)O3 system. These compounds all have monoclinic crystal structures similar to the pure alkali metal metavanadates containing small cations, e.g. Li+ and Na+ (Space group C2/c). Metavanadates with large cations like K+, Rb+, C+s and NH+4 form orthorhombic crystals, space group Pbcm. All those are structurally related to the silicate pyroxenes. Na(V0.66P0.34)O3 and (Na0.88K0.12)VO3 have the same modified diopside structure as (alpha) - NaVO3 while (Na0.5K0.5)VO3 adopts the true diopside structure. The infrared spectra of the three solid solutions are reported here in comparison with those of (alpha) -NaVO3 and KVO3. The results are also correlated with those obtained in two independent high pressure Raman studies of NH4VO3 and RbVO3 as the introduction of a larger cation like K+ should increase the pressure in the structure.
Eykyn, Thomas R.; Aksentijević, Dunja; Aughton, Karen L.; Southworth, Richard; Fuller, William; Shattock, Michael J.
2015-01-01
We investigate the potential of multiple quantum filtered (MQF) 23Na NMR to probe intracellular [Na]i in the Langendorff perfused mouse heart. In the presence of Tm(DOTP) shift reagent the triple quantum filtered (TQF) signal originated largely from the intracellular sodium pool with a 32 ± 6% contribution of the total TQF signal arising from extracellular sodium, whilst the rank 2 double-quantum filtered signal (DQF), acquired with a 54.7° flip-angle pulse, originated exclusively from the extracellular sodium pool. Given the different cellular origins of the 23Na MQF signals we propose that the TQF/DQF ratio can be used as a semi-quantitative measure of [Na]i in the mouse heart. We demonstrate a good correlation of this ratio with [Na]i measured with shift reagent at baseline and under conditions of elevated [Na]i. We compare the measurements of [Na]i using both shift reagent and TQF/DQF ratio in a cohort of wild type mouse hearts and in a transgenic PLM3SA mouse expressing a non-phosphorylatable form of phospholemman, showing a modest but measurable elevation of baseline [Na]i. MQF filtered 23Na NMR is a potentially useful tool for studying normal and pathophysiological changes in [Na]i, particularly in transgenic mouse models with altered Na regulation. PMID:26196304
Veiras, Luciana C.; Guevara, Claire A.; Ralph, Donna L.
2017-01-01
The World Health Organization ranks hypertension the leading global risk factor for disease, specifically, cardiovascular disease. Blood pressure (BP) is higher in Westernized populations consuming Na+-rich processed foods than in isolated societies consuming K+-rich natural foods. Evidence suggests that lowering dietary Na+ is particularly beneficial in hypertensive individuals who consume a high-Na+ diet. Nonetheless, numerous population studies demonstrate a relationship between higher dietary K+, estimated from urinary excretion or dietary recall, and lower BP, regardless of Na+ intake. Interventional studies with K+ supplementation suggest that it provides a direct benefit; K+ may also be a marker for other beneficial components of a “natural” diet. Recent studies in rodent models indicate mechanisms for the K+ benefit: the distal tubule Na+-Cl− cotransporter (NCC) controls Na+ delivery downstream to the collecting duct, where Na+ reabsorbed by epithelial Na+ channels drives K+ secretion and excretion through K+ channels in the same region. High dietary K+ provokes a decrease in NCC activity to drive more K+ secretion (and Na+ excretion, analogous to the actions of a thiazide diuretic) whether Na+ intake is high or low; low dietary K+ provokes an increase in NCC activity and Na+ retention, also independent of dietary Na+. Together, the findings suggest that public health efforts directed toward increasing consumption of K+-rich natural foods would reduce BP and, thus, cardiovascular and kidney disease. PMID:28174181
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-20
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2011-09-01
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Allen, D G; Eisner, D A; Lab, M J; Orchard, C H
1983-12-01
Papillary muscles from the right ventricles of ferrets were micro-injected with the photoprotein aequorin. Both tension and the light emitted by the aequorin, which is a measure of the free intracellular Ca concentration [( Ca2+]i), were monitored. Exposure of the papillary muscle to a solution in which all the Na had been replaced by K (0 Na(K) solution) resulted in an increase in tension which subsequently slowly decreased. This contracture was associated with a large increase in [Ca2+]i followed by a decrease to a steady-state-level which was often significantly greater than that in Na-containing solutions. If choline, Li or Tris was used instead of K as a substitute for Na, both the contracture and the associated increase of [Ca2+]i were reduced. The effects of depolarization alone (by raising external K at constant Na concentration) were compared with those of Na removal alone (at constant external K concentration). Na removal contributes more than depolarization to the effects of a Na-free, K-containing solution on the contracture and rise of [Ca2+]i. Increasing intracellular Na concentration [( Na+]i), by exposure to strophanthidin (10 mumol/l), increased the magnitude of both the contracture and [Ca2+]i in 0 Na(K) solutions. Conversely, decreasing [Na+]i by exposure to a solution containing a decreased extracellular Na concentration [( Na+]o), decreased the contracture and [Ca2+]i. When contractures were produced by solutions with various [Na+]o, the size of the resulting contracture and [Ca2+]i were inversely related to [Na+]o. No contracture was seen unless [Na+]o was reduced to below 70 mmol/l. A decrease in the extracellular Ca concentration [( Ca2+]o) from 2 to 0.5 mmol/l or an increase to 8 mmol/l produced, respectively, large decreases and increases of the twitch and accompanying Ca transient. However, if [Ca2+]o was changed at the same time as Na was replaced by K there was little effect on either the contracture or the rise of [Ca2+]i. If [Ca2+]o was changed before replacing Na by K then increasing [Ca2+]o from 2 to 8 mmol/l decreased, and decreasing [Ca2+]o from 2 to 0.5 mmol/l increased, the rise of [Ca2+]i produced by replacing Na by K. The difference between this result and that obtained when [Ca2+]o was changed at the same time as Na was removed may be due to changes of [Na+]i produced by prolonged exposure to an altered [Ca2+]o.(ABSTRACT TRUNCATED AT 400 WORDS)
[Effect of NaHCO3 stress on uptake and transportation of Na+, K+ and Ca2+ in three shrub species].
Mao, Gui-Lian; Li, Guo-Qi; Xu, Xing; Zhang, Xin-Xue
2014-03-01
We detected absorption and transportation of ions in the leaves of Atriplex nummularia, Atriplex canescens and Lycium barbarum under NaHCO3 stress (300 mmol x L(-1)) by using atomic absorption spectrophotometry and non-invasive ion flux measurement. The results showed that leaves of the A. nummularia, A. canescens and L. barbarum exhibited a high capacity to induce the Na+ accumulation when compared with that of control. The higher the concentration of NaHCO3 treatment, the more Na+ accumulated in the leaves of the three plants under experimental condition. L. barbarum showed a higher Na+ efflux in the mesophyll cells, whereas A. nummularia and A. canescens showed a relative lower efflux. A lower K+ content and a higher Na+/K+ ratio were detected in leaves of A. nummularia and L. barbarum. However, a higher K+ content and a lower Na+/K+ ratio were seen in leaves of A. canescens. Due to induction of Ca2+ efflux under the NaHCO3 treatment, a lower Ca2+ content and a higher Na+/Ca2+ ratio were observed in L. barbarum. On the contrary, a higher Ca2+ influx was observed in A. nummularia and A. canescens. These results suggested that the three shrubs species had different Na+ segmentation strategies. The accumulation of Na+ inhibited Ca2+ absorption in leaves of L. barbarum, while in the A. nummularia and A. canescens, Ca2+ influx induced [Ca2+]cyt which preserved a less-depolarized PM and then inhibited K efflux. The maintaining of cellular K+/Na+ homeostasis in A. nummularia and A. canescens might be achieved by the induction of [Ca2+]cyt under the NaHCO3 treatment.
Sodium and Potassium Fluxes and Compartmentation in Roots of Atriplex and Oat 1
Mills, David; Robinson, Kenneth; Hodges, Thomas K.
1985-01-01
K+ and Na+ fluxes and ion content have been studied in roots of Atriplex nummularia Lindl. and Avena sativa L. cv Goodfield grown in 3 millimolar K+ with or without 3 or 50 millimolar NaCl. Compartmental analysis was carried out with entire root systems under steady-state conditions. Increasing ambient Na+ concentrations from 0 to 50 millimolar altered K+, in Atriplex, as follows: slightly decreased the cytoplasmic content (Qc), the vacuolar content (Qv), and the plasma membrane influx and efflux. Xylem transport for K+ decreased by 63% in Atriplex. For oat roots, similar increases in Na+ altered K+ parameters as follows: plasma membrane influx and efflux decreased by about 80%. Qc decreased by 65%, and xylem transport decreased by 91%. No change, however, was observed in Qv for K+. Increasing ambient Na+ resulted in higher (3 to 5-fold) Na+ fluxes across the plasma membrane and in Qc of both species. In Atriplex, Na+ fluxes across the tonoplast and Qv increased as external Na+ was increased. In oat, however, no significant change was observed in Na+ flux across the tonoplast or in Qv as external Na+ was increased. In oat roots, Na+ reduced K+ uptake markedly; in Atriplex, this was not as pronounced. However, even at high Na+ levels, the influx transport system at the plasma membrane of both species preferred K+ over Na+. Based upon the Ussing-Teorell equation, it was concluded that active inward transport of K+ occurred across the plasma membrane, and passive movement of K+ occurred across the tonoplast in both species. Na+, in oat roots, was actively pumped out of the cytoplasm to the exterior, whereas, in Atriplex, Na+ was passively distributed between the free space, cytoplasm, and vacuole. PMID:16664273
Sodium and potassium fluxes and compartmentation in roots of atriplex and oat.
Mills, D; Robinson, K; Hodges, T K
1985-07-01
K(+) and Na(+) fluxes and ion content have been studied in roots of Atriplex nummularia Lindl. and Avena sativa L. cv Goodfield grown in 3 millimolar K(+) with or without 3 or 50 millimolar NaCl. Compartmental analysis was carried out with entire root systems under steady-state conditions.Increasing ambient Na(+) concentrations from 0 to 50 millimolar altered K(+), in Atriplex, as follows: slightly decreased the cytoplasmic content (Q(c)), the vacuolar content (Q(v)), and the plasma membrane influx and efflux. Xylem transport for K(+) decreased by 63% in Atriplex. For oat roots, similar increases in Na(+) altered K(+) parameters as follows: plasma membrane influx and efflux decreased by about 80%. Q(c) decreased by 65%, and xylem transport decreased by 91%. No change, however, was observed in Q(v) for K(+). Increasing ambient Na(+) resulted in higher (3 to 5-fold) Na(+) fluxes across the plasma membrane and in Q(c) of both species. In Atriplex, Na(+) fluxes across the tonoplast and Q(v) increased as external Na(+) was increased. In oat, however, no significant change was observed in Na(+) flux across the tonoplast or in Q(v) as external Na(+) was increased. In oat roots, Na(+) reduced K(+) uptake markedly; in Atriplex, this was not as pronounced. However, even at high Na(+) levels, the influx transport system at the plasma membrane of both species preferred K(+) over Na(+).Based upon the Ussing-Teorell equation, it was concluded that active inward transport of K(+) occurred across the plasma membrane, and passive movement of K(+) occurred across the tonoplast in both species. Na(+), in oat roots, was actively pumped out of the cytoplasm to the exterior, whereas, in Atriplex, Na(+) was passively distributed between the free space, cytoplasm, and vacuole.
Fernández-Pastor, Begoña; Mateo, Yolanda; Gómez-Urquijo, Sonia; Javier Meana, J
2005-07-01
The origin and regulation of noradrenaline (NA) in the locus coeruleus (LC) is unknown. The neurochemical features of NA overflow (nerve impulse dependence, neurotransmitter synthesis, vesicle storage, reuptake, alpha2-adrenoceptor-mediated regulation) were characterized in the LC. Brain microdialysis was performed in awake rats. Dialysates were analyzed for NA. NA in the LC decreased via local infusion of Ca2+-free medium (-42+/-5%) or the sodium channel blocker tetrodotoxine (TTX) (-47+/-8%) but increased (333+/-40%) via KCl-induced depolarization. The tyrosine hydroxylase (TH) inhibitor alpha-methyl-p-tyrosine (250 mg kg(-1), i.p.) and the vesicle depletory drug reserpine (5 mg kg(-1), i.p.) decreased NA. Therefore, extracellular NA in the LC satisfies the criteria for an impulse flow-dependent vesicular exocytosis of neuronal origin. Local perfusion of the alpha2-adrenoceptor agonist clonidine (0.1-100 microM) decreased NA (E(max)=-79+/-5%) in the LC, whereas the opposite effect (E(max)=268+/-53%) was observed with the alpha2A-adrenoceptor antagonist BRL44408 (0.1-100 microM). This suggests a tonic modulation of NA release through local alpha2A-adrenoceptors. The selective NA reuptake inhibitor desipramine (DMI) (0.1-100 microM) administered into the LC increased NA in the LC (E(max)=223+/-40%) and simultaneously decreased NA in the cingulate cortex, confirming the modulation exerted by NA in the LC on firing activity of noradrenergic cells and on the subsequent NA release in noradrenergic terminals. Synaptic processes underlying NA release in the LC are similar to those in noradrenergic terminal areas. NA in the LC could represent local somatodendritic release, but also the presence of neurotransmitter release from collateral axon terminals.
Perry, Steve F.
2016-01-01
The effects of acute exposure to acidic water on Na+ and Cl− homeostasis, and the mechanisms underlying their compensatory regulation, were investigated in the larval zebrafish Danio rerio. Exposure to acidic water (pH 4.0; control pH 7.6) for 2 h significantly reduced Na+ uptake and whole body Na+ content. Nevertheless, the capacity for Na+ uptake was substantially increased in fish preexposed to acidic water but measured in control water. Based on the accumulation of the Na+-selective dye, Sodium Green, two ionocyte subtypes exhibited intracellular Na+ enrichment after preexposure to acidic water: H+-ATPase rich (HR) cells, which coexpress the Na+/H+ exchanger isoform 3b (NHE3b), and a non-HR cell population. In fish experiencing Na+-Cl− cotransporter (NCC) knockdown, we observed no Sodium Green accumulation in the latter cell type, suggesting the non-HR cells were NCC cells. Elimination of NHE3b-expressing HR cells did not prevent the increased Na+ uptake following acid exposure. On the other hand, the increased Na+ uptake was abolished when the acidic water was enriched with Na+ and Cl−, but not with Na+ only, indicating that the elevated Na+ uptake after acid exposure was associated with the compensatory regulation of Cl−. Further examinations demonstrated that acute acid exposure also reduced whole body Cl− levels and increased the capacity for Cl− uptake. Moreover, knockdown of NCC prevented the increased uptake of both Na+ and Cl− after exposure to acidic water. Together, the results of the present study revealed a novel role of NCC in the compensatory regulation of Na+ and Cl− uptake following acute acidosis. PMID:27784676
Swapnil, Prashant; Rai, Ashwani K
2018-05-01
Soil salinity in nature is generally mixed type; however, most of the studies on salt toxicity are performed with NaCl and little is known about sulfur type of salinity (Na 2 SO 4 ). Present study discerns the physiologic mechanisms responsible for salt tolerance in salt-adapted Anabaena fertilissima, and responses of directly stressed parent cells to NaCl and NaCl+Na 2 SO 4 mixture. NaCl at 500 mM was lethal to the cyanobacterium, whereas salt-adapted cells grew luxuriantly. Salinity impaired gross photosynthesis, electron transport activities, and respiration in parent cells, but not in the salt-adapted cells, except a marginal increase in PSI activity. Despite higher Na + concentration in the salt mixture, equimolar NaCl appeared more inhibitive to growth. Sucrose and trehalose content and antioxidant activities were maximal in 250 mM NaCl-treated cells, followed by salt mixture and was almost identical in salt-adapted (exposed to 500 mm NaCl) and control cells, except a marginal increase in ascorbate peroxidase activity and an additional fourth superoxide dismutase isoform. Catalase isoform of 63 kDa was induced only in salt-stressed cells. Salinity increased the uptake of intracellular Na + and Ca 2+ and leakage of K + in parent cells, while cation level in salt-adapted cells was comparable to control. Though there was differential increase in intracellular Ca 2+ under different salt treatments, ratio of Ca 2+ /Na + remained the same. It is inferred that stepwise increment in the salt concentration enabled the cyanobacterium to undergo priming effect and acquire robust and efficient defense system involving the least energy.
Lee, So Young; Damodaran, Puthanveettil Narayanankutty; Roh, Kwang Soo
2014-01-01
The present study was designed to evaluate the influence of salicylic acid (SA) on the growth of salt stress (sodium chloride) induced in tobacco plants. In addition, quantification of rubisco and rubisco activase contents of the plants was also determined in treatments with the control, 10−4 mM SA, 50 mM NaCl, 100 mM NaCl, 150 mM NaCl, SA + 50 mM NaCl, SA + 100 mM NaCl and SA + 150 mM NaCl, respectively after in vitro culture for 5 weeks. The growth of the tobacco plant decreased in 50 mM and 100 mM NaCl when not treated with SA. However, the growth was accelerated by SA, and the growth retardation caused by NaCl was improved by SA. The content of rubisco was improved by SA only in plants treated with 50 mM NaCl, and the activity of rubisco was increased by SA resulting in the decreased effect of NaCl, but only in 50 mM NaCl treated plants. The content of rubisco activase decreased due to NaCl, and SA did not improve the effect caused by NaCl. The activity of rubisco activase was increased by SA resulting in decreased activity caused by NaCl, but increased effect by SA was not recovered to the level of NaCl untreated plants. The activity of rubisco and rubisco activase, which decreased due to denaturing agents, did not demonstrate significant improvement when compared to the control. PMID:25313276
Zhou, Aifen; Baidoo, Edward; He, Zhili; Mukhopadhyay, Aindrila; Baumohl, Jason K; Benke, Peter; Joachimiak, Marcin P; Xie, Ming; Song, Rong; Arkin, Adam P; Hazen, Terry C; Keasling, Jay D; Wall, Judy D; Stahl, David A; Zhou, Jizhong
2013-01-01
Desulfovibrio vulgaris Hildenborough strains with significantly increased tolerance to NaCl were obtained via experimental evolution. A NaCl-evolved strain, ES9-11, isolated from a population cultured for 1200 generations in medium amended with 100 mM NaCl, showed better tolerance to NaCl than a control strain, EC3-10, cultured for 1200 generations in parallel but without NaCl amendment in medium. To understand the NaCl adaptation mechanism in ES9-11, we analyzed the transcriptional, metabolite and phospholipid fatty acid (PLFA) profiles of strain ES9-11 with 0, 100- or 250 mM-added NaCl in medium compared with the ancestral strain and EC3-10 as controls. In all the culture conditions, increased expressions of genes involved in amino-acid synthesis and transport, energy production, cation efflux and decreased expression of flagellar assembly genes were detected in ES9-11. Consistently, increased abundances of organic solutes and decreased cell motility were observed in ES9-11. Glutamate appears to be the most important osmoprotectant in D. vulgaris under NaCl stress, whereas, other organic solutes such as glutamine, glycine and glycine betaine might contribute to NaCl tolerance under low NaCl concentration only. Unsaturation indices of PLFA significantly increased in ES9-11. Branched unsaturated PLFAs i17:1 ω9c, a17:1 ω9c and branched saturated i15:0 might have important roles in maintaining proper membrane fluidity under NaCl stress. Taken together, these data suggest that the accumulation of osmolytes, increased membrane fluidity, decreased cell motility and possibly an increased exclusion of Na+ contribute to increased NaCl tolerance in NaCl-evolved D. vulgaris. PMID:23575373
NASA Technical Reports Server (NTRS)
Williams, R. M.; Wheeler, B. L.; Jeffries-Nakamura, B.; Loveland, M. E.; Bankston, C. P.
1988-01-01
The effects of adding Na2MoO4 and Na2WO4 to porous Mo and W electrodes, respectively, on the performance and impedance characteristics of the electrodes in an alkali metal thermoelectric converter (AMTEC) were investigated. It was found that corrosion of the porous electrode by Na2MoO4 or Na2WO4 to form Na2MO3O6 and WO2, respectively, and recrystallization of the Mo or W as the salt evaporates, result in major morphological changes including a loss of columnar structure and a significant increase in porosity. This effect is more pronounced in Na2MoO4/Mo electrodes, due to the lower stability of Na2MoO4.
Intracellular Requirements for Passive Proton Transport through the Na+,K+-ATPase.
Stanley, Kevin S; Meyer, Dylan J; Gatto, Craig; Artigas, Pablo
2016-12-06
The Na + ,K + -ATPase (NKA or Na/K pump) hydrolyzes one ATP to exchange three intracellular Na+ (Na + i ) for two extracellular K+ (K + o ) across the plasma membrane by cycling through a set of reversible transitions between phosphorylated and dephosphorylated conformations, alternately opening ion-binding sites externally (E2) or internally (E1). With subsaturating [Na + ] o and [K + ] o , the phosphorylated E2P conformation passively imports protons generating an inward current (I H ), which may be exacerbated in NKA-subunit mutations associated with human disease. To elucidate the mechanisms of I H , we studied the effects of intracellular ligands (transported ions, nucleotides, and beryllium fluoride) on I H and, for comparison, on transient currents measured at normal Na + o (Q Na ). Utilizing inside-out patches from Xenopus oocytes heterologously expressing NKA, we observed that 1) in the presence of Na + i , I H and Q Na were both activated by ATP, but not ADP; 2) the [Na + ] i dependence of I H in saturating ATP showed K 0.5,Na = 1.8 ± 0.2 mM and the [ATP] dependence at saturating [Na + ] i yielded K 0.5,ATP = 48 ± 11 μM (in comparison, Na + i -dependent Q Na yields K 0.5,Na = 0.8 ± 0.2 mM and K 0.5,ATP = 0.43 ± 0.03 μM; 3) ATP activated I H in the presence of K + i (∼15% of the I H observed in Na + i ) only when Mg 2+ i was also present; and 4) beryllium fluoride induced maximal I H even in the absence of nucleotide. These data indicate that I H occurs when NKA is in an externally open E2P state with nucleotide bound, a conformation that can be reached through forward Na/K pump phosphorylation of E1, with Na + i and ATP, or by backward binding of K + i to E1, which drives the pump to the occluded E2(2K), where free P i (at the micromolar levels found in millimolar ATP solutions) promotes external release of occluded K + by backdoor NKA phosphorylation. Maximal I H through beryllium-fluorinated NKA indicates that this complex mimics ATP-bound E2P states. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.
Duarte, Rafael M; Benaduce, Ana Paula; Garcia, Luciano; Gomes, Levy C; Gomes, Adriana Chippari; Val, Adalberto L; Baldisserotto, Bernardo
2018-04-24
Formation water (FoW) is a by-product from oil and gas production and usually has high concentrations of soluble salts and metals. Calcium (Ca) and magnesium (Mg) have been shown to reduce the toxicity of metals to aquatic animals, and previous study showed that high waterborne Ca exerts mild effect against disturbances on Na + regulation in Amazonian armored catfish tamoatá (Hoplosternum littorale) acutely exposed to high Fe, Mn, and Ba levels. Here, we hypothesized that high Mg levels might also reduce the toxic effects of these metals on Na + regulation of tamoatá. The exposure to 5% FoW promoted an increase in Na + uptake and a rapid accumulation of Na + in all tissues analyzed (kidney
Di Benedetto, Mélanie; Starzec, Anna; Colombo, Bruno M; Briane, Dominique; Perret, Gérard Y; Kraemer, Michel; Crépin, Michel
2002-04-01
1. Since the sodium phenylacetate (NaPa) was reported to enhance the inhibitory effect of carboxymethyl benzylamide dextran (CMDB) on the breast cancer growth, we performed the esterification of CMDB with NaPa to obtain a new drug carrying the characteristics of these two components. A new molecule, phenylacetate carboxymethyl benzylamide dextran, was named NaPaC. 2. We investigated in vitro and in vivo the effects of NaPaC on MCF-7ras cell growth as well as its apoptotic and antiangiogenic effects in comparison to NaPa and CMDB. In addition, we assessed in vitro the antiproliferative effects of these drugs on other breast cancer cells, including MDA-MB-231, MDA-MB-435 and MCF-7. 3. In vitro, NaPaC inhibited MCF-7ras cell proliferation by 40% at concentration lower than that of CMDB and NaPa (12 microM vs 73 microM and 10 mM). IC(50)s were 6 and 28 microM for NaPaC and CMDB, respectively. The similar results were obtained for three other breast cancer cell lines. NaPaC reduced the DNA replication and induced cell recruitment in G(0)/G(1) phase more efficiently than its components. Moreover, it induced a cell death at concentration 1000-fold lower than NaPa. 4. In vivo, CMDB (150 mg kg(-1)) and NaPa (40 mg kg(-1)) inhibited the MCF-7ras tumour growth by 37 and 57%, respectively, whereas NaPaC (15 mg kg(-1)) decreased tumour growth by 66% without toxicity. 5. NaPa or CMDB reduced the microvessel number in tumour by 50% after 7 weeks of treatment. NaPaC had the same effect after only 2 weeks. After 7 weeks, it generated a large necrosis area without detectable microvessels. In vitro, NaPaC inhibited human endothelial cell proliferation more efficiently than CMDB or NaPa. NaPaC interacts with vascular endothelial growth factor as observed by affinity electrophoresis. 6. NaPaC acts like NaPa and CMDB but in more potent manner than components used separately. Its antiproliferative, aponecrotic and anti-angiogenic actions make it a good candidate for a new anti-cancer drug.
Dependence of renal (Na+ + k+)-adenosine triphosphatase activity on thyroid status.
Lo, S C; August, T R; Liberman, U A; Edelman, I S
1976-12-25
In thyroidectomized rats, a single injection of L-2,,5,2'-triiodothyronine (T3) (50mug/100 g body weight) elicited at 45% increase in (Na+ + k+)-dependent adenosine triphosphatase (NaK-ATPase) activity of the membrane-rich fraction of renal cortex at the optimal time of response, 48 h after injection. Three successive doses of T3 (50 mug/100 g body weight), given on alternate days, increased NaK-ATPase by 67% in the renal cortex but had no significant effect on the outer medulla or the papilla. Moreover, T3 had no effect on Mg2+-dependent adenosine trisphatase (MgATPase) in cortex, cedulla, or papilla. Three doses of T3 (50 mug/100 g body weight) given on alternate days to thyroidectomized rats elecited a 134, 79, and 46% increase in Vmax for ATP, Na4, and K+, respectively. There were no changes in the Km for ATP or the K1/2 values for Na+ and K+. Two methods were used to estimate the effect of T3 on the number of NaK-ATPase units (assumed to represent the number of Na+ pump sites); rat renal plasma membrane fractions were incubated with [gamma-32P]ATP, Mg2+, and Na+; the 32P-labeled membrane protein yeild was quantitatively dependent on Na+ and was hydrolyzed on addition of K+. There was a linear correlation between the specific activity of NaK-ATPase (Vmax) and the amount of phosphorylated intermediate formed, in renal cortical membrane fractions from thyroidectomized rats given T3 or the diluent. There was also a linear correlation between the specific activity of NaK-ATPase (Vmax) and the amount of [3H]ouabain specifically bound (Na+-, Mg2+-, APT-dependent) to the NaK-ATPase preparation. Injection of T3 resulted in a 70% increase in NaK-ATPase activity, a 79% increase in formation of the phosphorylated intermediate, and a 65% increase in the [H]ouabain specifically bound to the NaK-ATPase system. The T3-dependent increases in Vmax for ATP, Na+, and K+ and the proportionate increases in the phosphorylated intermediate and in the amount of [3H]ouabain bound indicate that T3 increases the number of NaK-ATPase units and that this increase accounts for the increase in NaK-ATPase activity.
NASA Astrophysics Data System (ADS)
Masłowska, Bogna; Ziółkowski, Jacek
1994-05-01
MnV 2O 6 of the brannerite-type structure (below 540°C) doped with MoO 3 and Na 2O forms isomorphous solid solutions MnNaφ = Mn 1- x-yφ xNa yV 2-2 x-yMo 2 x+ yO 6 (φ cation vacancy in the original Mn position), belonging to the pseudoternary MnV 2O 6-NaVMoO 6-MoO 3 system. Particular cases are MnNa = Mn 1- yNa y V 2- yMo yO 6 ( x = 0), Mnφ = Mn 1- xφ xV 2-2 xMo 2 xO 6 ( y = 0), and Naφ = Na 1- xφ xV 1- xMo 1+ xO 6 ( x + y = 1). MnV 2O 6 and NaVMoO 6 show miscibility in the entire composition range (MnNa). The opposite boundary of MnNaφ passes through the (100 x, 100 y) points (45, 0), (33, 30), and (30, 70). The phase diagram of the pseudobinary MnV 2O 6-NaVMoO 6 system (determined with DTA) shows (i) a narrow double-lens-type solidus-liquidus gap at high values of y , (ii) two peritectic meltings at lower y (yielding the high temperature β-MnNa and Mn 2V 2O 7), and (iii) little area of β-MnNa. Lattice parameters of MnNa (determined with X-ray diffraction) reveal small deviations from Vegard's law. As the ionic radii of both dopants (Na + and Mo 6+) are, respectively, larger than those of mother ions (Mn 2+ and V 5+), the unit cell increases in all directions with rising y along the MnNa series of solid solutions. However, due to the anisotropy of the structure, parameter c is strongly sensitive to Na/Mn substitution, b is ruled by Mo/V, and a is weakly influenced by Mo/V. Close analogy to the behavior of the previously studied MnV 2O 6-LiVMoO 6-MoO 6 system is discussed.
Using Electrolyte Free Water Balance to Rationalize and Treat Dysnatremias.
Shah, Sanjeev R; Bhave, Gautam
2018-01-01
Dysnatremias or abnormalities in plasma [Na + ] are often termed disorders of water balance, an unclear physiologic concept often confused with changes in total fluid balance. However, most clinicians clearly recognize that hypertonic or hypotonic gains or losses alter plasma [Na + ], while isotonic changes do not modify plasma [Na + ]. This concept can be conceptualized as the electrolyte free water balance (EFWB), which defines the non-isotonic components of inputs and outputs to determine their effect on plasma [Na + ]. EFWB is mathematically proportional to the rate of change in plasma [Na + ] (dP Na /dt) and, therefore, is actively regulated to zero so that plasma [Na + ] remains stable at its homeostatic set point. Dysnatremias are, therefore, disorders of EFWB and the relationship between EFWB and dP Na /dt provides a rationale for therapeutic strategies incorporating mass and volume balance. Herein, we leverage dP Na /dt as a desired rate of correction of plasma [Na + ] to define a stepwise approach for the treatment of dysnatremias.
Wang, Chaojian; Chung, Ben C.; Yan, Haidun; Wang, Hong-Gang; Lee, Seok-Yong; Pitt, Geoffrey S.
2014-01-01
Ca2+ regulates voltage-gated Na+ (NaV) channels and perturbed Ca2+ regulation of NaV function is associated with epilepsy syndromes, autism, and cardiac arrhythmias. Understanding the disease mechanisms, however, has been hindered by a lack of structural information and competing models for how Ca2+ affects NaV channel function. Here, we report the crystal structures of two ternary complexes of a human NaV cytosolic C-terminal domain (CTD), a fibroblast growth factor homologous factor, and Ca2+/calmodulin (Ca2+/CaM). These structures rule out direct binding of Ca2+ to the NaV CTD, and uncover new contacts between CaM and the NaV CTD. Probing these new contacts with biochemical and functional experiments allows us to propose a mechanism by which Ca2+ could regulate NaV channels. Further, our model provides hints towards understanding the molecular basis of the neurologic disorders and cardiac arrhythmias caused by NaV channel mutations. PMID:25232683
Liang, Zhicong; Fan, Xiaofeng; Zheng, Weitao; Singh, David J
2017-05-24
Layered carbon is a likely anode material for Na-ion batteries (NIBs). Graphitic carbon has a low capacity of approximately 35 (mA h)/g due to the formation of NaC 64 . Using first-principles methods including van der Waals interactions, we analyze the adsorption of Na ions and clusters on graphene in the context of anodes. The interaction between Na ions and graphene is found to be weak. Small Na clusters are not stable on the surface of pristine graphene in the electrochemical environment of NIBs. However, we find that Na ions and clusters can be stored effectively on defected graphene that has double vacancies. In addition, the adsorption energy of small Na clusters near a double vacancy is found to decrease with increasing cluster size. With high concentrations of vacancies the capacity of Na on defective graphene is found to be as much as 10-30 times higher than that of graphitic carbon.
Sodium-metal halide and sodium-air batteries.
Ha, Seongmin; Kim, Jae-Kwang; Choi, Aram; Kim, Youngsik; Lee, Kyu Tae
2014-07-21
Impressive developments have been made in the past a few years toward the establishment of Na-ion batteries as next-generation energy-storage devices and replacements for Li-ion batteries. Na-based cells have attracted increasing attention owing to low production costs due to abundant sodium resources. However, applications of Na-ion batteries are limited to large-scale energy-storage systems because of their lower energy density compared to Li-ion batteries and their potential safety problems. Recently, Na-metal cells such as Na-metal halide and Na-air batteries have been considered to be promising for use in electric vehicles owing to good safety and high energy density, although less attention is focused on Na-metal cells than on Na-ion cells. This Minireview provides an overview of the fundamentals and recent progress in the fields of Na-metal halide and Na-air batteries, with the aim of providing a better understanding of new electrochemical systems. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A 100-kWt NaK-Cooled Space Reactor Concept for an Early-Flight Mission
NASA Astrophysics Data System (ADS)
Poston, David I.
2003-01-01
A stainless-steel (SS) sodium-potassium (NaK) cooled reactor could potentially be the first step in utilizing fission technology in space. The sum of all system-level experience for liquid-metal-cooled space reactors has been with NaK, including the SNAP-10a, the only reactor ever launched by the US. This paper describes a 100-kWt NaK reactor, the NaK-100, which is designed to be developed with minimal technical risk. In additional to NaK technology heritage, the NaK-100 uses a proven fuel-form (SS/UO2) and is designed for simplified system integration and testing. The pins are placed within a solid SS prism, and the NaK flows in an annulus between the pins and the prism. The nuclear and thermal-hydraulic performance of the NaK-100 is presented, as well as the major differences between the NaK-100 and SNAP-10a.
Integrated Control of Na Transport along the Nephron
Schnermann, Jürgen
2015-01-01
The kidney filters vast quantities of Na at the glomerulus but excretes a very small fraction of this Na in the final urine. Although almost every nephron segment participates in the reabsorption of Na in the normal kidney, the proximal segments (from the glomerulus to the macula densa) and the distal segments (past the macula densa) play different roles. The proximal tubule and the thick ascending limb of the loop of Henle interact with the filtration apparatus to deliver Na to the distal nephron at a rather constant rate. This involves regulation of both filtration and reabsorption through the processes of glomerulotubular balance and tubuloglomerular feedback. The more distal segments, including the distal convoluted tubule (DCT), connecting tubule, and collecting duct, regulate Na reabsorption to match the excretion with dietary intake. The relative amounts of Na reabsorbed in the DCT, which mainly reabsorbs NaCl, and by more downstream segments that exchange Na for K are variable, allowing the simultaneous regulation of both Na and K excretion. PMID:25098598
Highly conductive porous Na-embedded carbon nanowalls for high-performance capacitive deionization
NASA Astrophysics Data System (ADS)
Chang, Liang; Hu, Yun Hang
2018-05-01
Highly conductive porous Na-embedded carbon nanowalls (Na@C), which were recently invented, have exhibited excellent performance for dye-sensitized solar cells and electric double-layer capacitors. In this work, Na@C was demonstrated as an excellent electrode material for capacitive deionization (CDI). In a three-electrode configuration system, the specific capacity of the Na@C electrodes can achieve 306.4 F/g at current density of 0.2 A/g in 1 M NaCl, which is higher than that (235.2 F/g) of activated carbon (AC) electrodes. Furthermore, a high electrosorption capacity of 8.75 mg g-1 in 100 mg/L NaCl was obtained with the Na@C electrodes in a batch-mode capacitive deionization cell. It exceeds the electrosorption capacity (4.08 mg g-1) of AC electrodes. The Na@C electrode also showed a promising cycle stability. The excellent performance of Na@C electrode for capacitive deionization (CDI) can be attributed to its high electrical conductivity and large accessible surface area.
NASA Astrophysics Data System (ADS)
Parvan, V.; Mizrak, A.; Majumdar, I.; Ümsür, B.; Calvet, W.; Greiner, D.; Kaufmann, C. A.; Dittrich, T.; Avancini, E.; Lauermann, I.
2018-06-01
Either metallic Na or NaF were deposited onto Cu(In,Ga)Se2 surfaces and studied by photoelectron spectroscopy and surface photovoltage spectroscopy without breaking the ultra-high vacuum. The deposition of elemental Na at room temperature led to the formation of an intermediate Cu and Ga rich layer at the CIGSe surface, whereas for NaF the composition of the CIGSe surface remained unchanged. A metal like surface induced by an inverted near surface region with a reduced number of defect states was formed after the deposition of Na. Under the chosen experimental conditions, the near surface layer was independent on the amount of Na and stable in time. In contrast, the usage of NaF weakened the inversion and led to an increased band bending compared to the untreated CIGSe sample. The SPV signals decreased with proceeding time after the deposition of NaF.
Study of the quaternary Na+, K+//F-, Br-, NO 3 - reciprocal system using an innovative methodology
NASA Astrophysics Data System (ADS)
Morgunova, O. E.; Ukhanov, A. S.; Katasonova, E. A.; Trunin, A. S.; Surinskii, K. D.
2016-08-01
The topological structure of the quaternary Na+, K+//F-, Br-, NO 3 - system is studied using a computer-assisted research system. A tree of phases is constructed, and the eutectic characteristics of the secant triangle NaNO3-KBr-NaF, (equiv. %) 84.6 NaNO3-9.1 KBr-6.3 NaF, at 255.3°C are determined.
Gao, Shuang; Tanaka, Kunihiko; Gotoh, Taro M; Morita, Hironobu
2005-08-01
The Na(+) receptor that exists in the hepatoportal region plays an important role in postprandial natriuresis and the regulation of Na(+) balance during NaCl load. Thus it would be considered that a dysfunction of the hepatic Na(+) receptor might result in the elevation of arterial pressure under a condition of high NaCl diet. To elucidate this hypothesis, arterial pressure was continuously measured during three weeks of high NaCl diet (8% NaCl) in four groups of rats: (i) intact rats, (ii) rats with hepatic denervation (HD), (iii) rats with sinoaortic denervation (SAD), and (iv) rats with SAD+HD. During a 1-week normal NaCl diet period, there was no difference in arterial pressure among the four groups. A high NaCl diet had no influence on arterial pressure in intact or HD rats; however, it significantly increased by 11 +/- 3 mmHg in SAD rats. The addition of HD to SAD had no synergistic effect on arterial pressure; i.e., in SAD+HD rats, mean arterial pressure increased by 13 +/- 1 mmHg. In conclusion, sinoaortic baroreceptor, but not hepatic Na(+) receptor, has a significant role in the long-term regulation of arterial pressure on a high NaCl diet.
On the origin of high ionic conductivity in Na-doped SrSiO 3
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chien, Po-Hsiu; Jee, Youngseok; Huang, Chen
Understanding the local structure and ion dynamics is at the heart of ion conductor research. This paper reports on high-resolution solid-state 29Si, 23Na, and 17O NMR investigation of the structure, chemical composition, and ion dynamics of a newly discovered fast ion conductor, Na-doped SrSiO 3, which exhibited a much higher ionic conductivity than most of current oxide ion conductors. Quantitative analyses reveal that with a small dose (<10 mol%) of Na, the doped Na integrates into the SrSiO 3 structure to form Na xSr 1-xSiO 3-0.5x, and with >10 mol% Na doping, phase separation occurs, leading to the formation ofmore » an amorphous phase β-Na 2Si 2O 5 and a crystalline Sr-rich phase. Variable-temperature 23Na and 17O magic-angle-spinning NMR up to 618 °C have shown significant changes in Na ion dynamics at high temperatures but little oxide ion motion, suggesting that Na ions are responsible for the observed high ionic conductivity. In addition, β-Na 2Si 2O 5 starts to crystallize at temperatures higher than 480 °C with prolonged heating, resulting in reduction in Na+ motion, and thus degradation of ionic conductivity. This study has contributed critical evidence to the understanding of ionic conduction in Na-doped SrSiO 3 and demonstrated that multinuclear high-resolution and high-temperature solid-state NMR is a uniquely useful tool for investigating ion conductors at their operating conditions.« less
SIPP, a Novel Mitochondrial Phosphate Carrier, Mediates in Self-Incompatibility1[OPEN
2017-01-01
In Solanaceae, the S-specific interaction between the pistil S-RNase and the pollen S-Locus F-box protein controls self-incompatibility (SI). Although this interaction defines the specificity of the pollen rejection response, the identification of three pistil essential modifier genes unlinked to the S-locus (HT-B, 120K, and NaStEP) unveils a higher degree of complexity in the pollen rejection pathway. We showed previously that NaStEP, a stigma protein with homology with Kunitz-type protease inhibitors, is essential to SI in Nicotiana spp. During pollination, NaStEP is taken up by pollen tubes, where potential interactions with pollen tube proteins might underlie its function. Here, we identified NaSIPP, a mitochondrial protein with phosphate transporter activity, as a novel NaStEP-interacting protein. Coexpression of NaStEP and NaSIPP in pollen tubes showed interaction in the mitochondria, although when expressed alone, NaStEP remains mostly cytosolic, implicating NaSIPP-mediated translocation of NaStEP into the organelle. The NaSIPP transcript is detected specifically in mature pollen of Nicotiana spp.; however, in self-compatible plants, this gene has accumulated mutations, so its coding region is unlikely to produce a functional protein. RNA interference suppression of NaSIPP in Nicotiana spp. pollen grains disrupts the SI by preventing pollen tube inhibition. Taken together, our results are consistent with a model whereby the NaStEP and NaSIPP interaction, in incompatible pollen tubes, might destabilize the mitochondria and contribute to arrest pollen tube growth. PMID:28874520
Pei, Ziwei; Bai, Ying; Wang, Yue; Wu, Feng; Wu, Chuan
2017-09-20
The lightweight compound material NaNH 2 -NaBH 4 is regarded as a promising hydrogen storage composite due to the high hydrogen density. Mechanical ball milling was employed to synthesize the composite NaNH 2 -NaBH 4 (2/1 molar ratio), and the samples were investigated utilizing thermogravimetric-differential thermal analysis-mass spectroscopy (TG-DTA-MS), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) analyses. The full-spectrum test (range of the ratio of mass to charge: 0-200) shows that the released gaseous species contain H 2 , NH 3 , B 2 H 6 , and N 2 in the heating process from room temperature to 400 °C, and possibly the impurity gas B 6 H 12 also exists. The TG/DTA analyses show that the composite NaNH 2 -NaBH 4 (2/1 molar ratio) is conductive to generate hydrogen so that the dehydrogenation process can be finished before 400 °C. Moreover, the thermal decomposition process from 200 to 400 °C involves two-step dehydrogenation reactions: (1) Na 3 (NH 2 ) 2 BH 4 hydride decomposes into Na 3 BN 2 and H 2 (200-350 °C); (2) remaining Na 3 (NH 2 ) 2 BH 4 reacts with NaBH 4 and Na 3 BN 2 , generating Na, BN, NH 3 , N 2 , and H 2 (350-400 °C). The better mechanism understanding of the thermal decomposition pathway lays a foundation for tailoring the hydrogen storage performance of the composite complex hydrides system.
2016-01-01
Firing patterns differ between subpopulations of vestibular primary afferent neurons. The role of sodium (NaV) channels in this diversity has not been investigated because NaV currents in rodent vestibular ganglion neurons (VGNs) were reported to be homogeneous, with the voltage dependence and tetrodotoxin (TTX) sensitivity of most neuronal NaV channels. RT-PCR experiments, however, indicated expression of diverse NaV channel subunits in the vestibular ganglion, motivating a closer look. Whole cell recordings from acutely dissociated postnatal VGNs confirmed that nearly all neurons expressed NaV currents that are TTX-sensitive and have activation midpoints between −30 and −40 mV. In addition, however, many VGNs expressed one of two other NaV currents. Some VGNs had a small current with properties consistent with NaV1.5 channels: low TTX sensitivity, sensitivity to divalent cation block, and a relatively negative voltage range, and some VGNs showed NaV1.5-like immunoreactivity. Other VGNs had a current with the properties of NaV1.8 channels: high TTX resistance, slow time course, and a relatively depolarized voltage range. In two NaV1.8 reporter lines, subsets of VGNs were labeled. VGNs with NaV1.8-like TTX-resistant current also differed from other VGNs in the voltage dependence of their TTX-sensitive currents and in the voltage threshold for spiking and action potential shape. Regulated expression of NaV channels in primary afferent neurons is likely to selectively affect firing properties that contribute to the encoding of vestibular stimuli. PMID:26936982
Overgaard-Steensen, Christian; Larsson, Anders; Bluhme, Henrik; Tønnesen, Else; Frøkiaer, Jørgen; Ring, Troels
2010-01-01
Acute hyponatremia is a serious condition, which poses major challenges. Of particular importance is what determines plasma sodium concentration ([Na(+)]). Edelman introduced an explicit model to describe plasma [Na(+)] in a population as [Na(+)] = alpha.(exchangeable Na(+) + exchangeable K(+))/(total body water) - beta. Evidence for the clinical utility of the model in the individual and in acute hyponatremia is sparse. We, therefore, investigated how the measured plasma [Na(+)] could be predicted in a porcine model of hyponatremia. Plasma [Na(+)] was estimated from in vivo-determined balances of water, Na(+), and K(+), according to Edelman's equation. Acute hyponatremia was induced with desmopressin acetate and infusion of a 2.5% glucose solution in anesthetized pigs. During 480 min, plasma [Na(+)] and osmolality were reduced from 136 (SD 2) to 120 mmol/l (SD 3) and from 284 (SD 4) to 252 mosmol/kgH(2)O (SD 5), respectively. The following interpretations were made. First, Edelman's model, which, besides dilution, takes into account Na(+) and K(+), fits plasma [Na(+)] significantly better than dilution alone. Second, a common value of alpha = 1.33 (SD 0.08) and beta = -13.04 mmol/l (SD 7.68) for all pigs explains well the plasma [Na(+)] in the individual animal. Third, measured exchangeable Na(+) and calculated exchangeable Na(+) + K(+) per weight in the pigs are close to Edelman's findings in humans, whereby the methods are cross-validated. In conclusion, plasma [Na(+)] can be explained in the individual animal by external balances, according to Edelman's construct in acute hyponatremia.
Role of alkali carbonate and salt in topochemical synthesis of K1/2Na1/2NbO3 and NaNbO3 templates
NASA Astrophysics Data System (ADS)
Lee, Jae-Seok; Jeon, Jae-Ho; Choi, Si-Young
2013-11-01
Since the properties of lead-free piezoelectric materials have thus far failed to meet those of lead-based materials, either chemical doping or morphological texturing should be employed to improve the piezoelectric properties of lead-free piezoelectric ceramics. The goal of this study was to synthesize plate-like K1/2Na1/2NbO3 and NaNbO3 particles, which are the most favorable templates for morphological texturing of K1/2Na1/2NbO3 ceramics. To achieve this goal, Bi2.5Na3.5Nb5O18 precursors in a plate-like shape were first synthesized and subsequently converted into K1/2Na1/2NbO3 or NaNbO3 particles that retain the morphology of Bi2.5Na3.5Nb5O18. In this study, we found that sodium or potassium carbonate does not play a major role in converting the Bi2.5Na3.5Nb5O18 precursor to K1/2Na1/2NbO3 or NaNbO3, on the contrary to previous reports; however, the salt contributes to the conversion reaction. All synthesis processes have been performed via a molten salt method, and scanning electron microscopy, scanning probe microscopy, and inductively coupled plasma mass spectroscopy were used to characterize the synthesized K1/2Na1/2NbO3 or NaNbO3 templates.
Consumer detection and acceptability of reduced-sodium bread.
La Croix, Kimberly W; Fiala, Steven C; Colonna, Ann E; Durham, Catherine A; Morrissey, Michael T; Drum, Danna K; Kohn, Melvin A
2015-06-01
Bread is the largest contributor of Na to the American diet and excess Na consumption contributes to premature death and disability. We sought to determine the Na level at which consumers could detect a difference between reduced-Na bread and bread with typical Na content, and to determine if consumer sensory acceptability and purchase intent differed between reduced-Na bread and bread with typical Na content. Difference testing measured ability to detect differences in control bread and reduced-Na bread using two-alternative forced choice testing. Acceptability was measured using a nine-point hedonic scale and purchase intent was measured using a five-point purchase intent scale. Difference and acceptability testing were conducted in Portland, OR, USA in January 2013. Eighty-two consumers participated in difference testing and 109 consumers participated in acceptability testing. Consumers did not detect a difference in saltiness between the control bread and the 10 % reduced-Na bread, but did detect a difference between the control bread and bread reduced in Na content by 20 % and 30 %. Na reductions had no effect on consumer acceptability of sensory characteristics, including overall liking, appearance, aroma, flavour, sweetness, salt level and texture, or purchase intent. Reducing Na levels by up to 30 % in the sandwich bread tested did not affect consumer liking or purchase intent of the product. These results support national recommendations for small, incremental Na reductions in the food supply over time and assure bread manufacturers that sensory characteristics and consumer purchase intent of their products will be preserved after Na reductions occur.