Urotensin II induction of neonatal cardiomyocyte hypertrophy involves the CaMKII/PLN/SERCA 2a signaling pathway.

PubMed

Shi, Hongtao; Han, Qinghua; Xu, Jianrong; Liu, Wenyuan; Chu, Tingting; Zhao, Li

2016-05-25

Although studies have shown that Urotensin II (UII) can induce cardiomyocyte hypertrophy and UII-induced cardiomyocyte hypertrophy model has been widely used for hypertrophy research, but its precise mechanism remains unknown. Recent researches have demonstrated that UII-induced cardiomyocyte hypertrophy has a relationship with the changes of intracellular Ca(2+) concentration. Therefore, the aim of this study was to investigate the mechanisms of cardiomyocyte hypertrophy induced by UII and to explore whether the calcium/calmodulin-dependent protein kinase II (CaMKII)-mediated up-regulating of phospholamban (PLN) Thr17-phosphorylation signaling pathway contributed to UII-induced cardiomyocyte hypertrophy. Primary cultures of neonatal rat cardiomyocytes were stimulated for 48h with UII. Cell size, protein/DNA contents and intracellular Ca(2+) were determined. Phosphorylated and total forms of CaMKII, PLN and the total amount of serco/endo-plasmic reticulum ATPases (SERCA 2a) were quantified by western blot. The responses of cardiomyocytes to UII were also evaluated after pretreatment with the CaMKII inhibitor, KN-93. These results showed that UII increased cell size, protein/DNA ratio and intracellular Ca(2+), consistent with a hypertrophic response. Furthermore, the phosphorylation of CaMKII and its downstream target PLN (Thr17), SERCA 2a levels were up-regulated by UII treatment. Conversely, treatment with KN-93 reversed all those effects of UII. Taken together, the results suggest that UII can induce cardiomyocyte hypertrophy through CaMKII-mediated up-regulating of PLN Thr17-phosphorylation signaling pathway. Copyright © 2016 Elsevier B.V. All rights reserved.

The role of urotensin II and atherosclerotic risk factors in patients with slow coronary flow

PubMed Central

Şatıroğlu, Ömer; Emre Durakoğlugil, Murtaza; Çetin, Mustafa; Çiçek, Yüksel; Erdoğan, Turan; Duman, Hakan

2016-01-01

Background Slow coronary flow (SCF) is an angiographic finding characterized with delayed opacification of epicardial coronary arteries without obstructive coronary disease. Urotensin II (UII) is an important vascular peptide, which has an important role in hypertension, coronary artery disease, and vascular remodeling in addition to potent vasoconstrictor effect. Objectives We investigated UII levels, hypertension, and other atherosclerotic risk factors in patients with SCF, a variety of coronary artery disease. Methods We enrolled 14 patients with SCF and 29 subjects with normal coronary arteries without SCF. We compared the UII levels and the atherosclerotic risk factors between patients with SCF and control subjects with normal coronary flow. Results UII concentrations were significantly higher in patients with SCF compared to controls (711.0 ± 19.4 vs. 701.5 ± 27.2 ng/mL, p = 0.006). We detected a positive correlation between SCF and age (r = 0.476, p = 0.001), BMI (r = 0.404, p = .002), UII concentrations (r = 0.422, p = 0.006), and hypertension (r = 0.594, p = 0.001). Conclusion We identified increased UII levels in patients with SCF. We think that UII concentrations may be informative on SCF pathogenesis due to relationship with inflammation, atherosclerosis, and vascular remodeling. PMID:28180005

Urotensin II modulates hepatic fibrosis and portal hemodynamic alterations in rats.

PubMed

Kemp, William; Kompa, Andrew; Phrommintikul, Arintaya; Herath, Chandana; Zhiyuan, Jia; Angus, Peter; McLean, Catriona; Roberts, Stuart; Krum, Henry

2009-10-01

The influence of circulating urotensin II (UII) on liver disease and portal hypertension is unknown. We aimed to evaluate whether UII executes a pathogenetic role in the development of hepatic fibrosis and portal hypertension. UII was administered by continuous infusion over 4 wk in 20 healthy rats divided into three treatment groups, controls (saline, n = 7), low dose (UII, 1 nmol x kg(-1) x h(-1), n = 8), and high dose (UII, 3 nmol x kg(-1) x h(-1), n = 5). Hemodynamic parameters and morphometric quantification of fibrosis were assessed, and profibrotic cytokines and fibrosis markers were assayed in hepatic tissue. UII induced a significant dose-dependent increase in portal venous pressure (5.8 +/- 0.4, 6.4 +/- 0.3, and 7.6 +/- 0.7, respectively, P = 0.03). High-dose UII infusion was associated with an increase in hepatic transcript for transforming growth factor-beta (P < 0.05) and platelet-derived growth factor-beta (P = 0.06). Liver tissue hydroxyproline was elevated in the high-dose group (P < 0.05). No systemic hemodynamic alterations were noted. We concluded that UII infusion elevates portal pressure and induces hepatic fibrosis in normal rats. This response may be mediated via induction of fibrogenic cytokines. These findings have pathophysiological implications in human liver disease where increased plasma UII levels have been observed.

Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling

PubMed Central

Chen, Zhidan; Xu, Jiahong; Ye, Yong; Li, Yang; Gong, Hui; Zhang, Guoping; Wu, Jian; jia, Jianguo; Liu, Ming; Chen, Ying; Yang, Chunjie; Tang, Yu; Zhu, Yichun; Ge, Junbo; Zou, Yunzeng

2014-01-01

Cardiac side population cells (CSPs) are promising cell resource for the regeneration in diseased heart as intrinsic cardiac stem cells. However, the relative low ratio of CSPs in the heart limited the ability of CSPs to repair heart and improve cardiac function effectively under pathophysiological condition. Which factors limiting the proliferation of CSPs in diseased heart are unclear. Here, we show that urotensin II (UII) regulates the proliferation of CSPs by c-Jun N-terminal kinase (JNK) and low density lipoprotein receptor-related protein 6 (LRP6) signalling during pressure overload. Pressure overload greatly upregulated UII level in plasma, UII receptor (UT) antagonist, urantide, promoted CSPs proliferation and improved cardiac dysfunction during chronic pressure overload. In cultured CSPs subjected to mechanical stretch (MS), UII significantly inhibited the proliferation by UT. Nanofluidic proteomic immunoassay showed that it is the JNK activation, but not the extracellular signal-regulated kinase signalling, that involved in the UII-inhibited- proliferation of CSPs during pressure overload. Further analysis in vitro indicated UII-induced-phospho-JNK regulates phosphorylation of LRP6 in cultured CSPs after MS, which is important in the inhibitory effect of UII on the CSPs during pressure overload. In conclusion, UII inhibited the proliferation of CSPs by JNK/LRP6 signalling during pressure overload. Pharmacological inhibition of UII promotes CSPs proliferation in mice, offering a possible therapeutic approach for cardiac failure induced by pressure overload. PMID:24447593

Urotensin II contributes to collagen synthesis and up-regulates Egr-1 expression in cultured pulmonary arterial smooth muscle cells through the ERK1/2 pathway

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Wei; Cai, Zhifeng; Liu, Mengmeng

Aim: The objective of this study was to investigate the effects of urotensin II (UII) treatment on the proliferation and collagen synthesis of cultured rat pulmonary arterial smooth muscle cells (PASMCs) and to explore whether these effects are mediated by mitogen-activated protein kinase (MAPK) signaling pathways and early growth response 1 (Egr-1). Methods: The proliferation of cultured PASMCs stimulated with different doses of UII was detected by BrdU incorporation. The mRNA expression levels of procollagen I (procol I), procollagen III (procol III), extracellular regulated protein kinase 1/2 (ERK1/2), stress-stimulated protein kinase (Sapk), p38 MAPK (p38), and Egr-1 mRNA in culturedmore » PASMCs after treatment with UII, the UII-specific antagonist urantide, and the ERK1/2 inhibitor PD98059 were detected by real-time polymerase chain reaction (PCR), and the protein expression levels of procol I, procol III, phosphorylated (p)-ERK1/2, p-Sapk, p-p38, and Egr-1 were detected by Western blotting. Results: Treatment with UII increased the proliferation of cultured PASMCs in a dose-dependent manner (P < 0.05). However, treatment with urantide and PD98059 inhibited the promoting effect of UII on PASMC proliferation (P < 0.05). Real-time PCR analysis showed that UII up-regulated the expression of procol I, procol III, ERK1/2, Sapk, and Egr-1 mRNA (P < 0.05), but not p38 mRNA. However, the up-regulating effect of UII was inhibited by PD98059 and urantide. Western blotting analysis showed that UII increased the synthesis of collagen I, collagen III, p-ERK1/2, p-Sapk, and Egr-1, and these effects also were inhibited by PD98059 and urantide (P < 0.05). Conclusions: Egr-1 participates in the UII-mediated proliferation and collagen synthesis of cultured rat PASMCs via activation of the ERK1/2 signaling pathway.« less

Urotensin II receptor (UTR) exists in hyaline chondrocytes: a study of peripheral distribution of UTR in the African clawed frog, Xenopus laevis.

PubMed

Konno, Norifumi; Fujii, Yuya; Imae, Haruka; Kaiya, Hiroyuki; Mukuda, Takao; Miyazato, Mikiya; Matsuda, Kouhei; Uchiyama, Minoru

2013-05-01

Urotensin II (UII) and UII-related peptide (URP) exhibit diverse physiological actions including vasoconstriction, locomotor activity, osmoregulation, and immune response through UII receptor (UTR), which is expressed in the central nervous system and peripheral tissues of fish and mammals. In amphibians, only UII has been identified. As the first step toward elucidating the actions of UII and URP in amphibians, we cloned and characterized URP and UTR from the African clawed frog Xenopus laevis. Functional analysis showed that treatment of UII or URP with Chinese hamster ovary cells transfected with the cloned receptor increased the intracellular calcium concentration in a concentration-dependent manner, whereas the administration of the UTR antagonist urantide inhibited UII- or URP-induced Ca(2+) mobilization. An immunohistochemical study showed that UTR was expressed in the splenocytes and leukocytes isolated from peripheral blood, suggesting that UII and URP are involved in the regulation of the immune system. UTR was also localized in the apical membrane of the distal tubule of the kidney and in the transitional epithelial cells of the urinary bladder. This result supports the view that the UII/URP-UTR system plays an important role in osmoregulation of amphibians. Interestingly, immunopositive labeling for UTR was first detected in the chondrocytes of various hyaline cartilages (the lung septa, interphalangeal joint and sternum). The expression of UTR was also observed in the costal cartilage, tracheal cartilages, and xiphoid process of the rat. These novel findings probably suggest that UII and URP mediate the formation of the cartilaginous matrix. Copyright © 2013 Elsevier Inc. All rights reserved.

Plasma urotensin in human systolic heart failure.

PubMed

Ng, Leong L; Loke, Ian; O'Brien, Russell J; Squire, Iain B; Davies, Joan E

2002-12-03

Human urotensin II (UTN) has potent vasoactive and cardiostimulatory effects, acting on the G protein-linked receptor GPR14. Myocardial UTN expression is upregulated in heart failure, and UTN stimulates myocardial expression of the natriuretic peptides. We investigated plasma UTN levels in heart failure (HF; left ventricular systolic dysfunction) in comparison with plasma N-terminal pro-brain natriuretic peptide (N-BNP) levels. N-BNP and UTN were measured in plasma from 126 patients with HF and 220 age- and sex-matched controls. Both peptides were elevated in plasma of HF patients and were correlated (r(s)=0.35, P<0.001). In contrast to N-BNP, there was no relationship of plasma UTN with New York Heart Association (NYHA) class. Although plasma N-BNP showed a positive relationship with age and female sex, there was no such age-dependent change in plasma UTN, and control women had lower levels compared with control men. Receiver operating characteristic curves for the diagnosis of HF had areas of 0.90 and 0.86 for N-BNP and UTN, respectively (P<0.001 for both). Receiver operating characteristic curve area for diagnosis of NYHA class I HF with UTN was better than that with N-BNP. Plasma UTN is elevated in HF, which suggests a pathophysiological role for this peptide. Plasma UTN may be a useful alternative to N-BNP in the diagnosis of HF, inasmuch as its levels are elevated irrespective of age, sex, or NYHA class.

Essential hypertension and oxidative stress: New insights

PubMed Central

González, Jaime; Valls, Nicolás; Brito, Roberto; Rodrigo, Ramón

2014-01-01

Essential hypertension is a highly prevalent pathological condition that is considered as one of the most relevant cardiovascular risk factors and is an important cause of morbidity and mortality around the world. Despite the fact that mechanisms underlying hypertension are not yet fully elucidated, a large amount of evidence shows that oxidative stress plays a central role in its pathophysiology. Oxidative stress can be defined as an imbalance between oxidant agents, such as superoxide anion, and antioxidant molecules, and leads to a decrease in nitric oxide bioavailability, which is the main factor responsible for maintaining the vascular tone. Several vasoconstrictor peptides, such as angiotensin II, endothelin-1 and urotensin II, act through their receptors to stimulate the production of reactive oxygen species, by activating enzymes like NADPH oxidase and xanthine oxidase. The knowledge of the mechanism described above has allowed generating new therapeutic strategies against hypertension based on the use of antioxidants agents, including vitamin C and E, N-Acetylcysteine, polyphenols and selenium, among others. These substances have different therapeutic targets, but all represent antioxidant reinforcement. Several clinical trials using antioxidants have been made. The aim of the present review is to provide new insights about the key role of oxidative stress in the pathophysiology of essential hypertension and new clinical attempts to demonstrate the usefulness of antioxidant therapy in the treatment of hypertension. PMID:24976907

Libby Dam and Lake Koocanusa Project, Montana Left Bank Slope.

DTIC Science & Technology

1984-04-01

cut prior to a shower of minor rockfall which characterized the cut slope during morning thawing. He had fortunately overslept. With the loss of site...WZuO-OZ -Z Qzmn omwoo B-20 I z Z- U. I-i *i w w 20 * ~’ Iz In v CY w i li gi f+ + + *x-ZOO -ZJZU 0.&MOO B-21I r~*w u OD x le 0z _ _ _ - - - - - 4cj LIj...i -4i UI Z 00Z - uIwu) u r-w o C-46 ’Ii, ii 0 L U Gi 4 II’ U II :1 - J IIlill U I w ",h "I w1! - -I Nil I >.- 1 • l ( -- 9 -- % II ,r 11 at 0 - i i a

12 CFR 263.65 - Civil penalty inflation adjustments.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) First tier—$7,500. (ii) Second tier—$37,500. (iii) Third tier—$1,425,000. (3) 12 U.S.C. 1820(k)(6)(A)(ii...) 12 U.S.C. 1467a(i)(2)—$32,500. (ii) 12 U.S.C. 1467a(i)(3)—$32,500. (12) 12 U.S.C. 1467a(r): (i) 12 U.S.C. 1467a(r)(1)—$3,200. (ii) 12 U.S.C. 1467a(r)(2)—$32,500. (iii) 12 U.S.C. 1467a(r)(3)—$1,425,000...

12 CFR 263.65 - Civil penalty inflation adjustments.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) First tier—$7,500. (ii) Second tier—$37,500. (iii) Third tier—$1,425,000. (3) 12 U.S.C. 1820(k)(6)(A)(ii...) 12 U.S.C. 1467a(i)(2)—$32,500. (ii) 12 U.S.C. 1467a(i)(3)—$32,500. (12) 12 U.S.C. 1467a(r): (i) 12 U.S.C. 1467a(r)(1)—$3,200. (ii) 12 U.S.C. 1467a(r)(2)—$32,500. (iii) 12 U.S.C. 1467a(r)(3)—$1,425,000...

Diet History Questionnaire II (DHQ II) for U.S. and Canada | EGRP/DCCPS/NCI/NIH

Cancer.gov

The Diet History Questionnaire II (DHQ II) is a freely available food frequency questionnaire (FFQ) for use by researchers, clinicians, or educators to assess food and dietary supplement intakes. The Canadian version of DHQ II is still available, but there is a newer U.S. version, DHQ III.

The role of oxidative stress in the pathophysiology of hypertension.

PubMed

Rodrigo, Ramón; González, Jaime; Paoletto, Fabio

2011-04-01

Hypertension is considered to be the most important risk factor in the development of cardiovascular disease. An increasing body of evidence suggests that oxidative stress, which results in an excessive generation of reactive oxygen species (ROS), has a key role in the pathogenesis of hypertension. The modulation of the vasomotor system involves ROS as mediators of vasoconstriction induced by angiotensin II, endothelin-1 and urotensin-II, among others. The bioavailability of nitric oxide (NO), which is a major vasodilator, is highly dependent on the redox status. Under physiological conditions, low concentrations of intracellular ROS have an important role in the normal redox signaling maintaining vascular function and integrity. However, under pathophysiological conditions, increased levels of ROS contribute to vascular dysfunction and remodeling through oxidative damage. In human hypertension, an increase in the production of superoxide anions and hydrogen peroxide, a decrease in NO synthesis and a reduction in antioxidant bioavailability have been observed. In turn, antioxidants are reducing agents that can neutralize these oxidative and otherwise damaging biomolecules. The use of antioxidant vitamins, such as vitamins C and E, has gained considerable interest as protecting agents against vascular endothelial damage. Available data support the role of these vitamins as effective antioxidants that can counteract ROS effects. This review discusses the mechanisms involved in ROS generation, the role of oxidative stress in the pathogenesis of vascular damage in hypertension, and the possible therapeutic strategies that could prevent or treat this disorder.

U.S. EPA, Pesticide Product Label, PARASITE CONTROL CATTLE OIL, 09/11/1972

EPA Pesticide Factsheets

2011-04-21

I I II ~ - \\linersl Oil-94.8 'Iuluthion-2.0 X vlt"nf"el.O I,\\ERT 1!\\{;REDIEl'iTS-U.2 l: It 'I'llJ' ~,I I· i' (' I II " I :; \\ I II I! i (I!' I : ,I \\ I \\ I \\ .. ': I , • t', II ,II . , . I I, ", : I' I ...

Adsorption of Fe(II) and U(VI) to carboxyl-functionalized microspheres: The influence of speciation on uranyl reduction studied by titration and XAFS

NASA Astrophysics Data System (ADS)

Boyanov, Maxim I.; O'Loughlin, Edward J.; Roden, Eric E.; Fein, Jeremy B.; Kemner, Kenneth M.

2007-04-01

The chemical reduction of U(VI) by Fe(II) is a potentially important pathway for immobilization of uranium in subsurface environments. Although the presence of surfaces has been shown to catalyze the reaction between Fe(II) and U(VI) aqueous species, the mechanism(s) responsible for the enhanced reactivity remain ambiguous. To gain further insight into the U-Fe redox process at a complexing, non-conducting surface that is relevant to common organic phases in the environment, we studied suspensions containing combinations of 0.1 mM U(VI), 1.0 mM Fe(II), and 4.2 g/L carboxyl-functionalized polystyrene microspheres. Acid-base titrations were used to monitor protolytic reactions, and Fe K-edge and U L-edge X-ray absorption fine structure spectroscopy was used to determine the valence and atomic environment of the adsorbed Fe and U species. In the Fe + surface carboxyl system, a transition from monomeric to oligomeric Fe(II) surface species was observed between pH 7.5 and pH 8.4. In the U + surface carboxyl system, the U(VI) cation was adsorbed as a mononuclear uranyl-carboxyl complex at both pH 7.5 and 8.4. In the ternary U + Fe + surface carboxyl system, U(VI) was not reduced by the solvated or adsorbed Fe(II) at pH 7.5 over a 4-month period, whereas complete and rapid reduction to U(IV) nanoparticles occurred at pH 8.4. The U(IV) product reoxidized rapidly upon exposure to air, but it was stable over a 4-month period under anoxic conditions. Fe atoms were found in the local environment of the reduced U(IV) atoms at a distance of 3.56 Å. The U(IV)-Fe coordination is consistent with an inner-sphere electron transfer mechanism between the redox centers and involvement of Fe(II) atoms in both steps of the reduction from U(VI) to U(IV). The inability of Fe(II) to reduce U(VI) in solution and at pH 7.5 in the U + Fe + carboxyl system is explained by the formation of a transient, "dead-end" U(V)-Fe(III) complex that blocks the U(V) disproportionation pathway after the first electron transfer. The increased reactivity at pH 8.4 relative to pH 7.5 is explained by the reaction of U(VI) with an Fe(II) oligomer, whereby the bonds between Fe atoms facilitate the transfer of a second electron to the hypothetical U(V)-Fe(III) intermediate. We discuss how this mechanism may explain the commonly observed higher efficiency of uranyl reduction by adsorbed or structural Fe(II) relative to aqueous Fe(II).

U.S. EPA, Pesticide Product Label, MEADOWS HOUSEHOLD CONTACT AND RESIDUAL SPRAY, 05/25/1990

EPA Pesticide Factsheets

2011-04-14

... tieU. fte.s IIId other inIIII1 lilted below. Apply sunlC" until wilt. R.,.II n needed. ... Itt ...., 11 Willi nil "- • lilt '"" IlirtCtIJ II ,.... II c ••• ell:lII 'IU ... _ flcllilill. ...

Selective separation of uranium using alizarin red S (ARS)-modified anion-exchange resin or by flotation of U-ARS chelate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Khalifa, M.E.

An alizarin red S (ARS)-modified anion exchange resin was prepared by a simple reaction of ARS with the anion exchange Doulite A101 and used for the efficient sorption of uranium from aqueous media. The effect of various parameters on the sorption of U(VI) (pH effect, sorption kinetics, resin capacity and breakthrough curves) was investigated. The modified resin sorbs U(VI) over a wide range of pH (2.8--5) with a maximum sorption capacity of 0.68 mmol/g at pH 3.2 to 4.0. Iron(III), Zr(IV), Ti(IV), Cu(II), and Th(IV) ions are also sorbed to different extents, but Be(II), Bi(III), Ca(II), Mg(II), Pb(II), Hg(II), Zn(II),more » Cd(II), Al(III), Mn(II), Co(II) and Ni(II) are not sorbed; thus, conditions for separating U(VI) from these metal ions have been identified. For eluting U(VI) from the resin, 0.2 mol/L HCl was used and the recovery recorded was as high as 99.9%. The use of ARS is extended to float uranium quantitatively and selectively from aqueous media at pH {approx} 4 by using oleic acid as a surfactant. The different parameters affecting the flotation process have also been investigated. Uranium(VI) has been effectively separated from natural water samples and certified uranium ores using both procedures.« less

U.S. EPA, Pesticide Product Label, PUNCH MOSQUITO REPELLENT, 12/02/1974

EPA Pesticide Factsheets

2011-04-21

... f'j:~O; ;&11 c: ::." N I _II . " • .. v , • 111111 ,'! • ; o "I' crill , '", : II . U: cr0ii:t:" ,,%1. X '; 't-:t- U I ~ , . III: 111::;)0< i ;J:a:mo.J I '..I: ><0< ' < : lu·.2 • " • ...

Management Control Systems in Not-for-Profit Organizations: A Case Study.

DTIC Science & Technology

1982-12-01

UNCLASSIFIED F/G 5/1 NL mhmmhhhhhmhmmum IEIIEEIIIIIEEE EIIIIIIIIIIIIl Diiit 1.1_I220 H- M141116 MICROCOPY RESOLUION4 TEST CHART 14ATIONAL BUREAU Of... test case. C. RESEARCH RET HODS The first phase of the study was a review of current literature on management control procedures and systems in...RESOLUTION TEST CHART NATIONAL BUREAU 0f SIANDARD 96% A I II a U a .1 ii IiU- I! IA i -~ - U I -..................... I I ~ 3 ,’u!nAA~~ -~~j ~; Eu ~ II 8I~ ~B

Effect of pH and Fe/U ratio on the U(VI) removal rate by the synergistic effect of Fe(II) and O2

NASA Astrophysics Data System (ADS)

Fu, Yukui; Luo, Yingfeng; Fang, Qi; Xie, Yanpei; Wang, Zhihong; Zhu, Xiangyu

2018-02-01

As for the decommissioned uranium deposits of acid in-situ leaching, both of the concentrations of U(VI) and Fe(II) are relatively high in groundwater. In the presence of O2, the oxidation of Fe(II) into Fe(III) that forms Fe-hydroxides could effectively remove U(VI) in the forms of sorption or co-precipitation. In this process, pH condition and Fe content will have a significant effect on the U(VI) removal rate by the synergistic effect of Fe(II) and O2. In the present work, a series of batch experiments were carried out to investigate the effect of pH values and Fe/U mass ratio on the U(VI) removal rate by the synergistic effect of Fe(II) and O2. Experiment results show that the removal rate of U(VI) is mainly controlled by pH and secondly by Fe/U mass ratio. In the neutral conditions with pH at 7 and 8, the removal rate of U(VI) reaches up to 90% for all solutions with different initial Fe(II) concentrations. The optimal pH for the removal rate of U(VI) is above 7. In the acidic conditions with pH below 6, the effect of Fe/U mass ratio on the removal rate of U(VI) becomes more obvious and the optimal Fe/U mass ratio for U(VI) removal is 1:2.

12 CFR 263.65 - Civil penalty inflation adjustments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... tier—$7,500. (ii) Second tier—$37,500. (iii) Third tier—$1,375,000. (3) 12 U.S.C. 1820(k)(6)(A)(ii...) 12 U.S.C. 1467a(i)(3)-$32,500. (12) 12 U.S.C. 1467a(r): (i) 12 U.S.C. 1467a(r)(1)-$ 2,200. (ii) 12 U.S.C. 1467a(r)(2)-$32,500. (iii) 12 U.S.C. 1467a(r)(3)-$1,375,000. [73 FR 58032, Oct. 6, 2008, as...

Thirteen Week Oral Toxicity Study of WR238605 with a Thirteen Week Recovery Period in Rats. Volume 3 of 3

DTIC Science & Technology

1993-06-18

Page 1 REVISED PAGE A u STUDY Mfr CBM, INITIAL (77 DATE-y-Hl^. 5.0 7.0 Contract No.: DAMD17-92-C-2C01 Task Order No.: UIC-5B Study No.: 098 ® i...Report. The results will not be Page 6 REVISED PAGE /?. STUDY Mfr 2M INITIAL: (jLL i OATF- \\yjuftl.’ I I 1’ II II II II II II II...necessary) recovery animals. . Page 7 REVISED PAGE A,. INITIALIZE cninvwyO^g DATE: ><-/*’ fr ?. i u JU ft Contract No. Task Order No. Study No

Defense.gov Special Report: World War II: Turning Points

Science.gov Websites

Department of Defense Submit Search Turning points of World War II U.S. Marines rest in the field on landed several miles from his intended drop zone. Cook, 87, was among the handful of World War II -Day U.S. and Allied military veterans of World War II and contemporay warriors attended commemoration

Uranium(VI) reduction by nanoscale zero-valent iron in anoxic batch systems: the role of Fe(II) and Fe(III).

PubMed

Yan, Sen; Chen, Yongheng; Xiang, Wu; Bao, Zhengyu; Liu, Chongxuan; Deng, Baolin

2014-12-01

The role of Fe(II) and Fe(III) in U(VI) reduction by nanoscale zerovalent iron (nanoFe0) was investigated using two iron chelators 1,10-phenanthroline and triethanolamine (TEA) under a CO2-free anoxic condition. The results showed that U(VI) reduction was strongly inhibited by 1,10-phenanthroline and TEA in a pH range from 6.9 to 9.0. For instance, at pH 6.9 the observed U(VI) reduction rates decreased by 81% and 82% in the presence of 1,10-phenanthroline and TEA, respectively. The inhibition was attributed to the formation of stable complexes between 1,10-phenanthroline and Fe(II) or TEA and Fe(III). In the absence of iron chelators, U(VI) reduction can be enhanced by surface-bound Fe(II) on nanoFe0. Our results suggested that Fe(III) and Fe(II) possibly acted as an electron shuttle to ferry the electrons from nanoFe0 to U(VI), therefore a combined system with Fe(II), Fe(III) and nanoFe0 could facilitate U(VI) reductive immobilization in the contaminated groundwater.

Uranium(VI) reduction by nanoscale zero-valent iron in anoxic batch systems: The role of Fe(II) and Fe(III)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yan, Sen; Chen, Yongheng; Xiang, Wu

2014-12-01

The role of Fe(II) and Fe(III) on U(VI) reduction by nanoscale zerovalent iron (nanoFe0) was investigated using two iron chelators 1,10-phenanthroline and triethanolamine (TEA) under a CO2-free anoxic condition. The results showed U(VI) reduction was strongly inhibited by 1,10-phenanthroline and TEA in a pH range from 6.92 to 9.03. For instance, at pH 6.92 the observed U(VI) reduction rates decreased by 80.7% and 82.3% in the presence of 1,10-phenanthroline and TEA, respectively. The inhibition was attributed to the formation of stable complexes between 1,10-phenanthroline and Fe(II) or TEA and Fe(III). In the absence of iron chelators, U(VI) reduction can bemore » enhanced by surface-bound Fe(II) on nanoFe0. Our results suggested that Fe(III) and Fe(II) probably acted as an electron shuttle to mediate the transfer of electrons from nanoFe0 to U(VI), therefore a combined system with Fe(II), Fe(III) and nanoFe0 can facilitate the U(VI) reductive immobilization in the contaminated groundwater.« less

Competing retention pathways of uranium upon reaction with Fe(II)

NASA Astrophysics Data System (ADS)

Massey, Michael S.; Lezama-Pacheco, Juan S.; Jones, Morris E.; Ilton, Eugene S.; Cerrato, José M.; Bargar, John R.; Fendorf, Scott

2014-10-01

Biogeochemical retention processes, including adsorption, reductive precipitation, and incorporation into host minerals, are important in contaminant transport, remediation, and geologic deposition of uranium. Recent work has shown that U can become incorporated into iron (hydr)oxide minerals, with a key pathway arising from Fe(II)-induced transformation of ferrihydrite, (Fe(OH)3·nH2O) to goethite (α-FeO(OH)); this is a possible U retention mechanism in soils and sediments. Several key questions, however, remain unanswered regarding U incorporation into iron (hydr)oxides and this pathway's contribution to U retention, including: (i) the competitiveness of U incorporation versus reduction to U(IV) and subsequent precipitation of UO2; (ii) the oxidation state of incorporated U; (iii) the effects of uranyl aqueous speciation on U incorporation; and, (iv) the mechanism of U incorporation. Here we use a series of batch reactions conducted at pH ∼7, [U(VI)] from 1 to 170 μM, [Fe(II)] from 0 to 3 mM, and [Ca] at 0 or 4 mM coupled with spectroscopic examination of reaction products of Fe(II)-induced ferrihydrite transformation to address these outstanding questions. Uranium retention pathways were identified and quantified using extended X-ray absorption fine structure (EXAFS) spectroscopy, X-ray powder diffraction, X-ray photoelectron spectroscopy, and transmission electron microscopy. Analysis of EXAFS spectra showed that 14-89% of total U was incorporated into goethite, upon reaction with Fe(II) and ferrihydrite. Uranium incorporation was a particularly dominant retention pathway at U concentrations ⩽50 μM when either uranyl-carbonato or calcium-uranyl-carbonato complexes were dominant, accounting for 64-89% of total U. With increasing U(VI) and Fe(II) concentrations, U(VI) reduction to U(IV) became more prevalent, but U incorporation remained a functioning retention pathway. These findings highlight the potential importance of U(V) incorporation within iron oxides as a retention process of U across a wide range of biogeochemical environments and the sensitivity of uranium retention processes to operative (bio)geochemical conditions.

Competing retention pathways of uranium upon reaction with Fe(II)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Massey, Michael S.; Lezama Pacheco, Juan S.; Jones, Morris

Biogeochemical retention processes, including adsorption, reductive precipitation, and incorporation into host minerals, are important in contaminant transport, remediation, and geologic deposition of uranium. Recent work has shown that U can become incorporated into iron (hydr)oxide minerals, with a key pathway arising from Fe(II)-induced transformation of ferrihydrite, (Fe(OH)3•nH2O) to goethite (α-FeO(OH)); this is a possible U retention mechanism in soils and sediments. Several key questions, however, remain unanswered regarding U incorporation into iron (hydr)oxides and this pathway’s contribution to U retention, including: (i) the competitiveness of U incorporation versus reduction to U(IV) and subsequent precipitation of UO2; (ii) the oxidation statemore » of incorporated U; (iii) the effects of uranyl aqueous speciation on U incorporation; and, (iv) the mechanism of U incorporation. Here we use a series of batch reactions conducted at pH ~7, [U(VI)] from 1 to 170 μM, [Fe(II)] from 0 to 3 mM, and [Ca] at 0 or 4 mM) coupled with spectroscopic examination of reaction products of Fe(II)-induced ferrihydrite transformation to address these outstanding questions. Uranium retention pathways were identified and quantified using extended x-ray absorption fine structure (EXAFS) spectroscopy, x-ray powder diffraction, x-ray photoelectron spectroscopy, and transmission electron microscopy. Analysis of EXAFS spectra showed that 14 to 89% of total U was incorporated into goethite, upon reaction with Fe(II) and ferrihydrite. Uranium incorporation was a particularly dominant retention pathway at U concentrations ≤ 50 μM when either uranyl-carbonato or calcium-uranyl-carbonato complexes were dominant, accounting for 64 to 89% of total U. With increasing U(VI) and Fe(II) concentrations, U(VI) reduction to U(IV) became more prevalent, but U incorporation remained a functioning retention pathway. These findings highlight the potential importance of U(V) incorporation within iron oxides as a retention process of U across a wide range of biogeochemical environments and the sensitivity of uranium retention processes to operative (bio)geochemical conditions.« less

Uranium Reduction by Fe(II) in the Presence of Montmorillonite and Nontronite.

PubMed

Tsarev, Sergey; Waite, T David; Collins, Richard N

2016-08-02

Uranium(VI) interactions with three smectites (one montmorillonite and two nontronites - NAu1 and NAu2) were examined with 0, 1, and 2 mM aqueous concentrations of Fe(II) over the pH range of 3-9.5 in a background electrolyte of 100 mM NaCl and 1 mM CaCl2 in equilibration with 400 ppmv CO2(g) ([U(VI)] = 4 μM and 0.5 g smectite/L). In the absence of Fe(II), no differences were observed in the U(VI) sorption curves for the three clay minerals. In the presence of 1 or 2 mM Fe(II), under anoxic conditions, U(VI) uptake by the smectites changed slightly between ∼pH 3 and 6; however, uranium uptake increased significantly above ∼pH 6 and was proportional to the concentration of Fe(II) added to the system, particularly at pH values >8. The uptake of Fe(II) showed a sharp edge starting from ∼pH 6.5 with 95%-100% uptake occurring at pH values >7.5, with no difference observed between the iron-rich nontronites and montmorillonite. After 3 days of reaction at pH 7.6 (i.e., above the Fe(II) "sorption" edge), U(VI) was transformed to a mixture of U(IV) and U(VI) sorption complexes, and after 14 days of reaction, 100% of the U was found to be reduced to U(IV) in the form of nanocrystalline uraninite. In contrast, U remained as sorbed species until 14 days of reaction at pH 6.5. Ferrihydrite (NAu1), lepidocrocite, and magnetite (NAu2) were detected as secondary mineralization products upon reaction of the nontronites with Fe(II) but appeared to have no effect on the partitioning or speciation of uranium.

U.S. EPA, Pesticide Product Label, HEMPEL'S ANTIFOULING COMBIC 7699-5111 RED, 06/08/1989

EPA Pesticide Factsheets

2011-04-19

... II ... Dis ''''Ii" .d ,. II f" "ulss,n If U. Utt at tM h. .f ,lSticie. ."liu.ti.. .i1 .. ... PRACTiCM. TREATI'IENT IF SIIlUII(I. ',ill ,,..,11, • ht,lt "ntit, .f .ilt •• " "'itu. "htil stlllill If. ...

U.S. EPA, Pesticide Product Label, TASCO BRAND 8LB. CHLORDANE EMULSION, 12/10/1975

EPA Pesticide Factsheets

2011-04-13

... nell II ~ .. 1 •• lde ., , .. t,," WIll., " .. H ... er ,I,.., Clnthllt ••• tc. ThIlCll n t. ,art III ..... 3) A ..... bIM " , ... U.II •• 111. ~iI • ..." trlldI ... .. tIIIII tilt ... If .. ...

78 FR 69302 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

..., II-T, III-C, I-C, II-U, I-B, I-E, I-G, I-H, I-I, I-J, I-L, I-M, I-P, II-G, II-I, II-P, III-D, I-K, I..., I-H, I-I, I-J, I-L, I-M, I-P, II-G, II-I, II-P, III-D, I-K, I-N, I-O, I-S, II-E, II-L, II-M, II-R, I... 102(h) of CERCLA, to document that all environmental impacts associated with the DON's activities on...

U.S. EPA, Pesticide Product Label, DIAZINON 4 SPRAY, 10/04/1993

EPA Pesticide Factsheets

2011-04-21

... iIiHf III lill ~lflilf IIH ; Ii f ti' '11-III'n! 1]1 Ihfl JIlL III illi'l f 111"1 ,1111 III ILl Iltll! II', ~tlf II JII! ,11111 ' I'i, t $'1 it I Itit ,.11 jilt! if II! W!JIIU, JI I i II t J IL If '"' : If 5.:0 ...

NATO/CCMS Pilot Study Evaluation of Demonstrated and ...

EPA Pesticide Factsheets

... "! n'nKiliHli.in Svc lln: "SiU"vlfini^ii-r^.i?i"'-ii.rhl KuiKxIi^iiii'ii P'ri'i-l,^:-. wvl|i-.|| ;IT II -:IK Ill1:l|!|i llli'lu'-l! l| tf lur '.'1 M'|XA MI,-||II'I,| H ... |-|..HAOu<- |i.| l||l \\\\Vf ...

Metal Ions Removal Using Nano Oxide Pyrolox™ Material

NASA Astrophysics Data System (ADS)

Gładysz-Płaska, A.; Skwarek, E.; Budnyak, T. M.; Kołodyńska, D.

2017-02-01

The paper presents the use of Pyrolox™ containing manganese nano oxides used for the removal of Cu(II), Zn(II), Cd(II), and Pb(II) as well as U(VI) ions. Their concentrations were analyzed using the atomic absorption spectrometer SpectrAA 240 FS (Varian) as well as UV-vis method. For this purpose the static kinetic and equilibrium studies were carried out using the batch technique. The effect of solution pH, shaking time, initial metal ion concentrations, sorbent dosage, and temperature was investigated. The equilibrium data were analyzed using the sorption isotherm models proposed by Freundlich, Langmuir-Freundlich, Temkin, and Dubinin-Radushkevich. The kinetic results showed that the pseudo second order kinetic model was found to correlate the experimental data well. The results indicate that adsorption of Cu(II), Zn(II), Cd(II), and Pb(II) as well as U(VI) ions is strongly dependent on pH. The value of pH 4-7 was optimal adsorption. The time to reach the equilibrium was found to be 24 h, and after this time, the sorption percentage reached about 70%. Kinetics of Cu(II), Zn(II), Cd(II), Pb(II), and U(VI) adsorption on the adsorbent can be described by the pseudo second order rate equation. Nitrogen adsorption/desorption, infrared spectroscopy (FTIR), and scanning electron microscopy (SEM) measurements for adsorbent characterization were performed. Characteristic points of the double layer determined for the studied Pyrolox™ sample in 0.001 mol/dm3 NaCl solution are pHPZC = 4 and pHIEP < 2.

The Changing Face of War in Textbooks: Depictions of World War II and Vietnam, 1970-2009

ERIC Educational Resources Information Center

Lachmann, Richard; Mitchell, Lacy

2014-01-01

How have U.S. high school textbook depictions of World War II and Vietnam changed since the 1970s? We examined 102 textbooks published from 1970 to 2009 to see how they treated U.S. involvement in World War II and Vietnam. Our content analysis of high school history textbooks finds that U.S. textbooks increasingly focus on the personal experiences…

U.S. EPA, Pesticide Product Label, DACAMINE 2D/2T, 10/22/1971

EPA Pesticide Factsheets

2011-04-14

... tt.di ... _ .. ___ It is J ·s oM .. c.MeI ..... oM..,,. II j1:.~ .. oec" •• _n." .• . _ ' •. II .... , Ii' .. • . ef'""" III'" 'ItJill'I' ,..llbi.1 ..... t _ II II ..... tIIue .... . ...

The role of RNA structure in the interaction of U1A protein with U1 hairpin II RNA

PubMed Central

Law, Michael J.; Rice, Andrew J.; Lin, Patti; Laird-Offringa, Ite A.

2006-01-01

The N-terminal RNA Recognition Motif (RRM1) of the spliceosomal protein U1A interacting with its target U1 hairpin II (U1hpII) has been used as a paradigm for RRM-containing proteins interacting with their RNA targets. U1A binds to U1hpII via direct interactions with a 7-nucleotide (nt) consensus binding sequence at the 5′ end of a 10-nt loop, and via hydrogen bonds with the closing C–G base pair at the top of the RNA stem. Using surface plasmon resonance (Biacore), we have examined the role of structural features of U1hpII in binding to U1A RRM1. Mutational analysis of the closing base pair suggests it plays a minor role in binding and mainly prevents “breathing” of the loop. Lengthening the stem and nontarget part of the loop suggests that the increased negative charge of the RNA might slightly aid association. However, this is offset by an increase in dissociation, which may be caused by attraction of the RRM to nontarget parts of the RNA. Studies of a single stranded target and RNAs with untethered loops indicate that structure is not very relevant for association but is important for complex stability. In particular, breaking the link between the stem and the 5′ side of the loop greatly increases complex dissociation, presumably by hindering simultaneous contacts between the RRM and stem and loop nucleotides. While binding of U1A to a single stranded target is much weaker than to U1hpII, it occurs with nanomolar affinity, supporting recent evidence that binding of unstructured RNA by U1A has physiological significance. PMID:16738410

The role of RNA structure in the interaction of U1A protein with U1 hairpin II RNA.

PubMed

Law, Michael J; Rice, Andrew J; Lin, Patti; Laird-Offringa, Ite A

2006-07-01

The N-terminal RNA Recognition Motif (RRM1) of the spliceosomal protein U1A interacting with its target U1 hairpin II (U1hpII) has been used as a paradigm for RRM-containing proteins interacting with their RNA targets. U1A binds to U1hpII via direct interactions with a 7-nucleotide (nt) consensus binding sequence at the 5' end of a 10-nt loop, and via hydrogen bonds with the closing C-G base pair at the top of the RNA stem. Using surface plasmon resonance (Biacore), we have examined the role of structural features of U1hpII in binding to U1A RRM1. Mutational analysis of the closing base pair suggests it plays a minor role in binding and mainly prevents "breathing" of the loop. Lengthening the stem and nontarget part of the loop suggests that the increased negative charge of the RNA might slightly aid association. However, this is offset by an increase in dissociation, which may be caused by attraction of the RRM to nontarget parts of the RNA. Studies of a single stranded target and RNAs with untethered loops indicate that structure is not very relevant for association but is important for complex stability. In particular, breaking the link between the stem and the 5' side of the loop greatly increases complex dissociation, presumably by hindering simultaneous contacts between the RRM and stem and loop nucleotides. While binding of U1A to a single stranded target is much weaker than to U1hpII, it occurs with nanomolar affinity, supporting recent evidence that binding of unstructured RNA by U1A has physiological significance.

U.S. EPA, Pesticide Product Label, 3-INCH CHLORINATING TABLETS, 12/20/1973

EPA Pesticide Factsheets

2011-04-14

... '"j , II . \\ 1 i \\!; !' I !! -)' I 'JII' , In- Net W t. :100 Ibs. 11'\\ '"' f . I' (I tit .., I \\ II I \\ I' \\" I) II I \\ \\ \\ B\\TlIII: 10\\1) !.! . II()( k ,,' f..1 \\II \\ " ~,j i; I( t·, '". i \\ , , ", ...

New Bedford, Sampling and Analysis Data: References 34-60, 1976-1983

EPA Pesticide Factsheets

2012-04-22

... HIV u;nM in in :;i inn 'in iraii'MiLncniii, !i,i IB ii i T 11^1,111:111 imii«'; ncnl.Mr; i': 'ii ... r ii |: 'nii>i>eiri I: ji; I: :i vnn CD II: |M:I|:'',I. lu I: i i:>i: ej:p» i; Mire ILu nn ...

SphK1 inhibitor II (SKI-II) inhibits acute myelogenous leukemia cell growth in vitro and in vivo

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Li; Weng, Wei; Sun, Zhi-Xin

Previous studies have identified sphingosine kinase 1 (SphK1) as a potential drug target for treatment of acute myeloid leukemia (AML). In the current study, we investigated the potential anti-leukemic activity of a novel and specific SphK1 inhibitor, SKI-II. We demonstrated that SKI-II inhibited growth and survival of human AML cell lines (HL-60 and U937 cells). SKI-II was more efficient than two known SphK1 inhibitors SK1-I and FTY720 in inhibiting AML cells. Meanwhile, it induced dramatic apoptosis in above AML cells, and the cytotoxicity by SKI-II was almost reversed by the general caspase inhibitor z-VAD-fmk. SKI-II treatment inhibited SphK1 activation, andmore » concomitantly increased level of sphingosine-1-phosphate (S1P) precursor ceramide in AML cells. Conversely, exogenously-added S1P protected against SKI-II-induced cytotoxicity, while cell permeable short-chain ceramide (C6) aggravated SKI-II's lethality against AML cells. Notably, SKI-II induced potent apoptotic death in primary human AML cells, but was generally safe to the human peripheral blood mononuclear cells (PBMCs) isolated from healthy donors. In vivo, SKI-II administration suppressed growth of U937 leukemic xenograft tumors in severe combined immunodeficient (SCID) mice. These results suggest that SKI-II might be further investigated as a promising anti-AML agent. - Highlights: • SKI-II inhibits proliferation and survival of primary and transformed AML cells. • SKI-II induces apoptotic death of AML cells, but is safe to normal PBMCs. • SKI-II is more efficient than two known SphK1 inhibitors in inhibiting AML cells. • SKI-II inhibits SphK1 activity, while increasing ceramide production in AML cells. • SKI-II dose-dependently inhibits U937 xenograft growth in SCID mice.« less

Feasibility of processing the experimental breeder reactor-II driver fuel from the Idaho National Laboratory through Savannah River Site's H-Canyon facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Magoulas, V. E.

Savannah River National Laboratory (SRNL) was requested to evaluate the potential to receive and process the Idaho National Laboratory (INL) uranium (U) recovered from the Experimental Breeder Reactor II (EBR-II) driver fuel through the Savannah River Site’s (SRS) H-Canyon as a way to disposition the material. INL recovers the uranium from the sodium bonded metallic fuel irradiated in the EBR-II reactor using an electrorefining process. There were two compositions of EBR-II driver fuel. The early generation fuel was U-5Fs, which consisted of 95% U metal alloyed with 5% noble metal elements “fissium” (2.5% molybdenum, 2.0% ruthenium, 0.3% rhodium, 0.1% palladium,more » and 0.1% zirconium), while the later generation was U-10Zr which was 90% U metal alloyed with 10% zirconium. A potential concern during the H-Canyon nitric acid dissolution process of the U metal containing zirconium (Zr) is the explosive behavior that has been reported for alloys of these materials. For this reason, this evaluation was focused on the ability to process the lower Zr content materials, the U-5Fs material.« less

77 FR 47116 - Manufacturer of Controlled Substances; Notice of Registration; Penick Corporation

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-07

... Ecgonine (9180) II Hydrocodone (9193) VII Morphine (9300) II Oripavine (9330) II Thebaine (9333) II... has considered the factors in 21 U.S.C. 823(a) and determined that the registration of Penick...

Synthesis, structural characterization, and pro-apoptotic activity of 1-indanone thiosemicarbazone platinum(II) and palladium(II) complexes: potential as antileukemic agents.

PubMed

Gómez, Natalia; Santos, Diego; Vázquez, Ramiro; Suescun, Leopoldo; Mombrú, Alvaro; Vermeulen, Monica; Finkielsztein, Liliana; Shayo, Carina; Moglioni, Albertina; Gambino, Dinorah; Davio, Carlos

2011-08-01

In the search for alternative chemotherapeutic strategies against leukemia, various 1-indanone thiosemicarbazones, as well as eight novel platinum(II) and palladium(II) complexes, with the formula [MCl₂(HL)] and [M(HL)(L)]Cl, derived from two 1-indanone thiosemicarbazones were synthesized and tested for antiproliferative activity against the human leukemia U937 cell line. The crystal structure of [Pt(HL1)(L1)]Cl·2MeOH, where L1=1-indanone thiosemicarbazone, was solved by X-ray diffraction. Free thiosemicarbazone ligands showed no antiproliferative effect, but the corresponding platinum(II) and palladium(II) complexes inhibited cell proliferation and induced apoptosis. Platinum(II) complexes also displayed selective apoptotic activity in U937 cells but not in peripheral blood monocytes or the human hepatocellular carcinoma HepG2 cell line used to screen for potential hepatotoxicity. Present findings show that, in U937 cells, 1-indanone thiosemicarbazones coordinated to palladium(II) were more cytotoxic than those complexed with platinum(II), although the latter were found to be more selective for leukemic cells suggesting that they are promising compounds with potential therapeutic application against hematological malignancies. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Study to Modify the Vulnerability Model of the Risk Management System

DTIC Science & Technology

1980-02-01

Willar~d W ery’William P./ Azico1l ____________ 9. Performing Organization Name and Address 10 . Work Unit No. (TRAIS) Enviro Control, Inc. One Central...I ItIi 1i 1 T ii t 1 1 SIG j- i"j U’ 1Ilm 1111 ~ 1 jI I-.-I• . --•’ • ~ ~ll l itl [ rl / /l t jIe IIst I. !oia iii•’ I II III u ii U •It : p l f Pit i...and their results are fully described and dis- cussed in Chapter 5. ŕ- 10 5. Additional VN Program Hodificatlons In the process of performing the

Surface catalysis of uranium(VI) reduction by iron(II)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liger, E.; Charlet, L.; Van Cappellen, P.

1999-10-01

Colloidal hematite ({alpha}-Fe{sub 2}O{sub 3}) is used as model solid to investigate the kinetic effect of specific adsorption interactions on the chemical reduction of uranyl (U{sup VI}O{sub 2}{sup 2+}) by ferrous iron. Acid-base titrations and Fe(II) and uranyl adsorption experiments are performed on hematite suspensions, under O{sub 2}- and CO{sub 2}-free conditions. The results are explained in terms of a constant capacitance surface complexation model of the hematite-aqueous solution interface. Two distinct Fe(II) surface complexes are required to reproduce the data: ({equivalent{underscore}to}Fe{sup III}OFe{sup II}){sup +} (or {equivalent{underscore}to}Fe{sup III}OFe{sup II}(OH{sub 2}){sub n}{sup +}) and {equivalent{underscore}to}Fe{sup III}OFe{sup II}OH{sup 0} (or {equivalent{underscore}to}Fe{sup III}OFe{supmore » II}(OH{sub 2}){sub n{minus}1}OH{sup 0}). The latter complex represents a significant fraction of total adsorbed Fe(II) at pH {gt} 6.5. Uranyl binding to the hematite particles is characterized by a sharp adsorption edge between pH 4 and pH 5.5. Because of the absence of competing aqueous carbonate complexes, uranyl remains completely adsorbed at pH {gt} 7. A single mononuclear surface complex accounts for the adsorption of uranyl over the entire range of experimental conditions. Although thermodynamically feasible, no reaction between uranyl and Fe(II) is observed in homogeneous solution at pH 7.5, for periods of up to three days. In hematite suspensions, however, surface-bound uranyl reacts on a time scale of hours. Based on Fourier Transformed Infrared spectra, chemical reduction of U(VI) is inferred to be the mechanism responsible for the disappearance of uranyl. The kinetics of uranyl reduction are quantified by measuring the decrease with time of the concentration of U(VI) extractable from the hematite particles by NaHCO{sub 3}. In the presence of excess Fe(II), the initial rate of U(VI) reduction exhibits a first-order dependence on the concentration of adsorbed uranyl. The pseudo-first-order rate constant varies with pH (range, 6--7.5) and the total (dissolved + adsorbed) concentration of Fe(II) (range, 2--160 {micro}M). When analyzing the rate data in terms of the calculated surface speciation, the variability of the rate constant can be accounted for entirely by changes in the concentration of the Fe(II) monohydroxo surface complex {equivalent{underscore}to}Fe{sup III}OFe{sup II}OH{sup 0}. Therefore, the rate law is derived for the hematite-catalyzed reduction of uranyl by Fe(II), where the bimolecular rate constant {kappa} has a value of 399 {+-} 25 M{sup {minus}1} min{sup {minus}1} at 25 C. The hydroxo surface complex is the rate-controlling reductant species, because it provides the most favorable coordination environment in which electrons are removed from Fe(II). Natural particulate matter collected in the hypolimnion of a seasonally stratified lake also causes the rapid reduction of uranyl by Fe(II), Ferrihydrite, identified in the particulate matter by X-ray diffraction, is one possible mineral phase accelerating the reaction between U(VI) and Fe(II). At near-neutral pH and total Fe(II) levels less than 1 mM, the pseudo-first-order rate constants of chemical U(VI) reduction, measured in the presence of the hematite and lake particles, are of the same order of magnitude as the highest corresponding rate coefficients for enzymatic U(VI) reduction in bacterial cultures. Hence, based on the results of this study, surface-catalyzed U(VI) reduction by Fe(II) is expected to be a major pathway of uranium immobilization in a wide range of redox-stratified environments.« less

Characterization of PgPepO, a bacterial homologue of endothelin-converting enzyme-1.

PubMed

Carson, Julie A; Ansai, Toshihiro; Awano, Shuji; Yu, Weixian; Takehara, Tadamichi; Turner, Anthony J

2002-08-01

PgPepO is a homologue of endothelin-converting enzyme-1 (ECE-1), with which it shares 31% identity. PgPepO was isolated from the periodontal pathogen Porphyromonas gingivalis. Recent studies have suggested a link between periodontal and cardiovascular disease, and several groups have suggested that bacterial and viral infections may contribute to the latter. P. gingivalis possesses the ability to invade, and multiply within, aortic endothelial cells and has been localized to atherosclerotic plaques. PgPepO was expressed and purified to homogeneity and we have begun detailed functional analysis, in terms of substrate preference and inhibitor specificity, in order to provide active-site comparisons with other members of the neprilysin (NEP)/ECE family. PgPepO possesses similar substrate specificity to ECE-1 and has been shown to cleave big endothelin-1 (big ET-1), big ET-2 and big ET-3, converting the substrates into their respective mature endothelin peptides. Substance P, angiotensin I, angiotensin II and neurotensin are all cleaved at multiple sites by PgPepO and the kinetics of these reactions have been compared. The potent vasoconstrictor urotensin II is not hydrolysed by PgPepO. Cleavage of bradykinin by PgPepO occurs at the Pro(7)-Phe(8) bond and is inhibited by the NEP and ECE-1 inhibitor phosphoramidon in a pH-dependent fashion (IC(50) =10 microM at pH 7.0) but not by thiorphan, an NEP-specific inhibitor. PgPepO activity is completely inhibited by EDTA. Characterization of this enzyme is important in elucidating possible links between periodontal pathogens and cardiovascular disorders such as atherosclerosis, and provides an opportunity to gain structural information on a bacterial protein with striking similarity to human ECE-1.

Gaming the Interwar: How Naval War College Wargames Tilted the Playing Field for the U.S. Navy During World War II

DTIC Science & Technology

2013-12-13

GAMING THE INTERWAR: HOW NAVAL WAR COLLEGE WARGAMES TILTED THE PLAYING FIELD FOR THE U.S. NAVY DURING WORLD WAR II A thesis......ii MASTER OF MILITARY ART AND SCIENCE THESIS APPROVAL PAGE Name of Candidate: LCDR James A. Miller, USN Thesis Title: Gaming the Interwar

Role of major histocompatibility complex class II in the development of autoimmune type 1 diabetes and thyroiditis in rats

PubMed Central

Yokoi, N; Hidaka, S; Tanabe, S; Ohya, M; Ishima, M; Takagi, Y; Masui, N; Seino, S

2012-01-01

Although the MHC class II ‘u' haplotype is strongly associated with type 1 diabetes (T1D) in rats, the role of MHC class II in the development of tissue-specific autoimmune diseases including T1D and autoimmune thyroiditis remains unclear. To clarify this, we produced a congenic strain carrying MHC class II ‘a' and ‘u' haplotypes on the Komeda diabetes-prone (KDP) genetic background. The u/u homozygous animals developed T1D similar to the original KDP rat; a/u heterozygous animals did develop T1D but with delayed onset and low frequency. In contrast, none of the a/a homozygous animals developed T1D; about half of the animals with a/u heterozygous or a/a homozygous genotypes showed autoimmune thyroiditis. To investigate the role of genetic background in the development of thyroiditis, we also produced a congenic strain carrying Cblb mutation of the KDP rat on the PVG.R23 genetic background (MHC class II ‘a' haplotype). The congenic rats with homozygous Cblb mutation showed autoimmune thyroiditis without T1D and slight to severe alopecia, a clinical symptom of hypothyroidism such as Hashimoto's thyroiditis. These data indicate that MHC class II is involved in the tissue-specific development of autoimmune diseases, including T1D and thyroiditis. PMID:21918539

U.S. EPA, Pesticide Product Label, ACME WEED KILLER NON-SELECTIVE HERBICIDE FOR GENERAL WEED CONTROL, 09/20/1974

EPA Pesticide Factsheets

2011-04-21

... 1 , if" .,\\, II 11,,",,1 ,", \\' I It! « ) J I t II ( '" "\\ t. II f I . " .' ,11 I. ! "" ' ol \\ " t 1)"1' Ill' etf' f ('Il'" , 'I . " " " "I I ()'~ I'/" !" f III , ' I' ( II I I' 1111' II t " / ': I ') I '. ' " , ...

A first principles investigation of electron transfer between Fe(II) and U(VI) on insulating Al- vs. semiconducting Fe-oxide surfaces via the proximity effect

NASA Astrophysics Data System (ADS)

Taylor, S. D.; Marcano, M. C.; Becker, U.

2017-01-01

This study investigates how the intrinsic chemical and electronic properties of mineral surfaces and their associated electron transfer (ET) pathways influence the reduction of U(VI) by surface-associated Fe(II). Density functional theory (DFT), including the Hubbard U correction to the exchange-correlation functional, was used to investigate sorption/redox reactions and ET mechanisms between Fe(II) and U(VI) coadsorbed on isostructural, periodic (0 0 1) surfaces of the insulator corundum (α-Al2O3) vs. the semiconductor hematite (α-Fe2O3). Furthermore, the coadsorbed Fe(II) and U(VI) ions are spatially separated from one another on the surfaces (⩾5.9 Å) to observe whether electronic-coupling through the semiconducting hematite surface facilitates ET between the adsorbates, a phenomenon known as the proximity effect. The calculations show that the different chemical and electronic properties between the isostructural corundum and hematite (0 0 1) surfaces lead to considerably different ET mechanisms between Fe(II) and U(VI). ET on the insulating corundum (0 0 1) surface is limited by the adsorbates' structural configuration. When Fe(II) and U(VI) are spatially separated and do not directly interact with one another (e.g. via an inner-sphere complex), U(VI) reduction by Fe(II) cannot occur as there is no physical pathway enabling ET between the adsorbates. In contrast to the insulating corundum (0 0 1) surface, the hematite (0 0 1) surface can potentially participate in ET reactions due to the high number of electron acceptor sites from the Fe d-states near the Fermi level at the hematite surface. The adsorption of Fe(II) also introduces d-states near the Fermi level as well as shifts unoccupied d-states of the Fe cations at the hematite surface to lower energies, making the surface more conductive. In turn, electronic coupling through the surface can link the spatially separated adsorbates to one another and provide distinct ET pathways for an electron from Fe(II) to travel through the hematite surface and reach U(VI). The progression and extent of ET occurring on the semiconducting hematite (0 0 1) surface via the proximity effect depends on the electronic properties of the surface. ET between the spatially separated U(VI) and Fe(II) occurs most readily when orbitals between the Fe and U adsorbates overlap with those of neighboring O and Fe ions at the hematite surface, as shown by calculations without the Hubbard U correction. Analyses of the spins densities confirm that the U and Fe adsorbates were reduced and oxidized, respectively, (acquiring 0.33 μB and 0.11-0.20 μB, respectively), while Fe cations at the hematite surface were reduced (losing ⩽0.6 μB). If electrons are highly localized, the amount of orbital mixing and electronic coupling through the hematite surface decreases and in turn leads to a lower degree of spin transfer, as predicted by calculations with the Hubbard U correction. Thus, the proximity effect is a potential mechanism on semiconducting surfaces facilitating surface-mediated redox reactions, although its significance varies depending on the electronic properties and subsequent charge-carrying ability of the surface. These results provide insight into ET pathways and mechanisms on insulating Al- and semiconducting Fe oxide surfaces influencing the reduction U(VI) by Fe(II) that may subsequently limit uranium's transport in the subsurface.

U.S. EPA, Pesticide Product Label, , 05/30/1984

EPA Pesticide Factsheets

2011-04-14

... PlUt,' 11""1{\\ "'1\\11 'u " ... If \\ / ,It II ... II I If I '1 , , ... I' III I 'U \\' "t \\1 ... I \\1 1 I'" "1""'11 \\1111(1111 '111 \\1 11\\/\\1(11 h.,! " BORAX \\. t'\\ " I, ,,' 11',- I" ,,1:.- " . ...

Status Report on Speech Research, July-December 1981.

DTIC Science & Technology

1981-01-01

there is a difference in the intercept of the beat straight-line fit for /i-u/ and /u- u/ cases; that is, rounding for the second vowel begins earlier... BINAURAL ] PRESENTATION I I tI I I I I I I I •I II II I ,V III I P" J II I base isolated transitions (to one ear) (to other. ear) DUPLEX-PRODUCING...frequency modulation, particularly as they relate to classical auditory phenomena such as beats and periodicity pitch. In general, however, research on

U.S. EPA, Pesticide Product Label, FLIGHT BRAND TOXAPHENE-METHYL PARATHION EC 6-3, 06/04/1973

EPA Pesticide Factsheets

2011-04-14

I \\ " I'll )( 1 II \\ " " ! II.:. \\ I \\ I i J '1< I \\ I \\ 1 i :\\ : ( \\I I IIlH)' .. I'll' Sf(i \\ '\\ 1'(" "4)'\\1:\\(, \\ I Il' r I " S'\\1I'141'\\\\ \\ II \\ II l \\ \\' \\ \\ I( "t' \\ PH" H) I' \\!( \\ 1"" SIt 1.\\", \\ II BII \\ )\\\\ ...

Taxicab Regulation in U.S. Cities. Volume II, Case Studies

DOT National Transportation Integrated Search

1983-10-01

Volume II of the study, Taxicab Regulation in U.S. Cities, contains case study reports. Ten U.S. cities were visited in June and July, 1983, for more in-depth study of their experiences with taxicab regulation. These cities are Fayetteville and Charl...

Decontamination of TCE- and U-rich waters by granular iron: Role of sorbed Fe(II)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Charlet, L.; Liger, E.; Gerasimo, P.

1998-01-01

Uranium (UO{sub 2}{sup 2+}) and chlorinated aliphatics [tetrachloroethane (PCE) and trichloroethane (TCE)] can be reduced and thus immobilized or degraded, respectively, by the same abiotic mechanism. In this mechanism the reduction reaction is coupled to the oxidation of Fe(II) sorbed on iron corrosion products such as hematite. This is indicated by the equilibrium E{sub h} values measured during uranium immobilization and PCE degradation reactions of zerovalent iron. These values fit closely with those measured in the Fe(II)-{alpha}Fe{sub 2}O{sub 3}-H{sub 2}O system (in the absence of U or PCE), not those of the Fe(o)/Fe(II) or H{sub 2}(g)/H{sub 2}O couples. Because ironmore » (II) is very unstable in environments that are not strictly anaerobic, Fe(o) serves as a source of Fe(II). The reduction kinetic rate, analyzed in detail for the reduction of U(VI), is found to be a function of the concentration of OH{sup {minus}}, Fe{sup 2+} and reactive surface sites, and is given in terms of sorbed species concentrations by {l_brace}d[U(VI)]{sub ads}{r_brace}/dt = {l_brace}{minus}k{prime}[{triple_bond}FeOFeOH{sup 0}][U(VI)]{sub ads}{r_brace}. This rate law applies to organic pollutants as well, as long as they can be reduced by surface Fe(II): {l_brace}d[Pollutant]{r_brace}/dt = {l_brace}{minus}k{prime}[{triple_bond}FeOFeOH{sup 0}][Pollutant]{r_brace}. This mechanism suggests new possibilities for the improvement of low-cost decontamination techniques for U- and chlorinated aliphatic-rich waters.« less

78 FR 66984 - International Security Advisory Board (ISAB); Meeting Notice; Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... information, contact Richard W. Hartman II, Executive Director of the International Security Advisory Board, U.... Richard W. Hartman, II, Executive Director, International Security Advisory Board, U.S. Department of...

Cross-Cultural Validation of the Beck Depression Inventory-II across U.S. and Turkish Samples

ERIC Educational Resources Information Center

Canel-Cinarbas, Deniz; Cui, Ying; Lauridsen, Erica

2011-01-01

The purpose of this study was to test the Beck Depression Inventory-II (BDI-II) for factorial invariance across Turkish and U.S. college student samples. The results indicated that (a) a two-factor model has an adequate fit for both samples, thus providing evidence of configural invariance, and (b) there is a metric invariance but "no"…

Soviet Strong-Motion and Vibration-and-Blast Seismographs

DTIC Science & Technology

1975-07-01

wiv’ - ■" i’"!*-i.T’ ppwiit^iiMiJP^iw,!piiw;pw! Ji |.tfi.1^u UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE (When Datm Enlared) ~~~~ ^ REPORT...8217""’--"■• ^JJ^.-t1l^-»Jt.ii»^i^^&.-’:--->J-r.M^<iM|litimf • •■J"i"*-*^"’fcj--JL: ji ^.uiiijjm »■•IUW.-II.U ii" i Miiii«iMMiij»m*.ii 111,1.1 i.. -amm...III GB-IV Fig. 1 — Schematic drawing of the GB-III and GB-IV galvanometers [6] .^..■^Mi^a*.,^,^^,^,,,, ; ..; ..,.,■,,_.,■ ... . . ■ ji imw wm

25 CFR 547.3 - What are the definitions for this part?

Code of Federal Regulations, 2011 CFR

2011-04-01

... TECHNICAL STANDARDS FOR GAMING EQUIPMENT USED WITH THE PLAY OF CLASS II GAMES § 547.3 What are the... Commission. Class II game. The same as “class II gaming” in 25 U.S.C. 2703(7)(A). Class II gaming system. All..., that function together to aid the play of one or more Class II games, including accounting functions...

25 CFR 547.3 - What are the definitions for this part?

Code of Federal Regulations, 2012 CFR

2012-04-01

... TECHNICAL STANDARDS FOR GAMING EQUIPMENT USED WITH THE PLAY OF CLASS II GAMES § 547.3 What are the... Commission. Class II game. The same as “class II gaming” in 25 U.S.C. 2703(7)(A). Class II gaming system. All..., that function together to aid the play of one or more Class II games, including accounting functions...

25 CFR 547.3 - What are the definitions for this part?

Code of Federal Regulations, 2010 CFR

2010-04-01

... TECHNICAL STANDARDS FOR GAMING EQUIPMENT USED WITH THE PLAY OF CLASS II GAMES § 547.3 What are the... Commission. Class II game. The same as “class II gaming” in 25 U.S.C. 2703(7)(A). Class II gaming system. All..., that function together to aid the play of one or more Class II games, including accounting functions...

U.S. EPA, Pesticide Product Label, TOBACCO STATES BRAND 20% LINDANE TRANSPLANTER SOLUTION, 04/16/1984

EPA Pesticide Factsheets

2011-04-13

... I' If I ., '.,1' II ! 11\\ !., I,· III I .. , ' . II ., td' I'! I,d h .. rKI I ,,1 111'1 J '.' I. :'[ , t ,\\'. 10, ... I illj.,liI 1'1 "II t r,) 1 It .1;' II' L,',HI .If ,(I Ihq II.. ~lll 1),1: Ill'! '.LV('~I t 1, h ' ...

Fate of Adsorbed U(VI) during Sulfidization of Lepidocrocite and Hematite

PubMed Central

2017-01-01

The impact on U(VI) adsorbed to lepidocrocite (γ-FeOOH) and hematite (α-Fe2O3) was assessed when exposed to aqueous sulfide (S(-II)aq) at pH 8.0. With both minerals, competition between S(-II) and U(VI) for surface sites caused instantaneous release of adsorbed U(VI). Compared to lepidocrocite, consumption of S(-II)aq proceeded slower with hematite, but yielded maximum dissolved U concentrations that were more than 10 times higher, representing about one-third of the initially adsorbed U. Prolonged presence of S(-II)aq in experiments with hematite in combination with a larger release of adsorbed U(VI), enhanced the reduction of U(VI): after 24 h of reaction about 60–70% of U was in the form of U(IV), much higher than the 25% detected in the lepidocrocite suspensions. X-ray absorption spectra indicated that U(IV) in both hematite and lepidocrocite suspensions was not in the form of uraninite (UO2). Upon exposure to oxygen only part of U(IV) reoxidized, suggesting that monomeric U(IV) might have become incorporated in newly formed iron precipitates. Hence, sulfidization of Fe oxides can have diverse consequences for U mobility: in short-term, desorption of U(VI) increases U mobility, while reduction to U(IV) and its possible incorporation in Fe transformation products may lead to long-term U immobilization. PMID:28121137

SOLUTIA INC, RFI/MCP PHASE 2 COMPREHENSIVE SITE ASSESSMENT ADDENDUM REPORT WITH ENVIRONMENTAL & HUMAN HEALTH RISK CHARACTERIZATION - VOLUME 6 OF 6, 06-01-2007, RDMS# 105910

EPA Pesticide Factsheets

2014-12-04

... ( IHII|> U.ii(i..i. *>iiin|, | || I' > 4 |H .Ill-l'll/.l 1 ••li ii ii> : •• " in « - ji i **mi|i!i Dijilli illi M.IIHI.IIII- N\\ N\\ - II •- -ir *>iiii|ili liui. ... 1 MM « 11 1 1 llr)-(. ir \\ 1 HM'II ii'-i : ...

Investigation of Rotor Performance and Loads of a UH-60A Individual Blade Control System

NASA Technical Reports Server (NTRS)

Yeo, Hyeonsoo; Romander, Ethan A.; Norman, Thomas R.

2011-01-01

Wind tunnel measurements of performance, loads, and vibration of a full-scale UH-60A Black Hawk main rotor with an individual blade control (IBC) system are compared with calculations obtained using the comprehensive helicopter analysis CAMRAD II and a coupled CAMRAD II/OVERFLOW 2 analysis. Measured data show a 5.1% rotor power reduction (8.6% rotor lift to effective-drag ratio increase) using 2/rev IBC actuation with 2.0. amplitude at u = 0.4. At the optimum IBC phase for rotor performance, IBC actuator force (pitch link force) decreased, and neither flap nor chord bending moments changed significantly. CAMRAD II predicts the rotor power variations with IBC phase reasonably well at u = 0.35. However, the correlation degrades at u = 0.4. Coupled CAMRAD II/OVERFLOW 2 shows excellent correlation with the measured rotor power variations with IBC phase at both u = 0.35 and u = 0.4. Maximum reduction of IBC actuator force is better predicted with CAMRAD II, but general trends are better captured with the coupled analysis. The correlation of vibratory hub loads is generally poor by both methods, although the coupled analysis somewhat captures general trends.

Genome-Enabled Studies of Anaerobic, Nitrate-Dependent Iron Oxidation in the Chemolithoautotrophic Bacterium Thiobacillus denitrificans

NASA Astrophysics Data System (ADS)

Beller, H. R.; Zhou, P.; Legler, T. C.; Chakicherla, A.; O'Day, P. A.

2013-12-01

Thiobacillus denitrificans is a chemolithoautotrophic bacterium capable of anaerobic, nitrate-dependent U(IV) and Fe(II) oxidation, both of which can strongly influence the long-term efficacy of in situ reductive immobilization of uranium in contaminated aquifers. We previously identified two c-type cytochromes involved in nitrate-dependent U(IV) oxidation in T. denitrificans and hypothesized that c-type cytochromes would also catalyze Fe(II) oxidation, as they have been found to play this role in anaerobic phototrophic Fe(II)-oxidizing bacteria. Here we report on efforts to identify genes associated with nitrate-dependent Fe(II) oxidation, namely (a) whole-genome transcriptional studies [using FeCO3, Fe2+, and U(IV) oxides as electron donors under denitrifying conditions], (b) Fe(II) oxidation assays performed with knockout mutants targeting primarily highly expressed or upregulated c-type cytochromes, and (c) random transposon-mutagenesis studies with screening for Fe(II) oxidation. Assays of mutants for 26 target genes, most of which were c-type cytochromes, indicated that none of the mutants tested were significantly defective in nitrate-dependent Fe(II) oxidation. The non-defective mutants included the c1-cytochrome subunit of the cytochrome bc1 complex (complex III), which has relevance to a previously proposed role for this complex in nitrate-dependent Fe(II) oxidation and to current concepts of reverse electron transfer. Of the transposon mutants defective in Fe(II) oxidation, one mutant with a disrupted gene associated with NADH:ubiquinone oxidoreductase (complex I) was ~35% defective relative to the wild-type strain; this strain was similarly defective in nitrate reduction with thiosulfate as the electron donor. Overall, our results indicate that nitrate-dependent Fe(II) oxidation in T. denitrificans is not catalyzed by the same c-type cytochromes involved in U(IV) oxidation, nor have other c-type cytochromes yet been implicated in the process.

On the Effectiveness of Military Institutions: Historical Case Studies from World War I, The Interwar Period, and World War II. Volume 3. World War II

DTIC Science & Technology

1986-04-01

ting the claims of U the tortured economy against those et the reeling military organization. I I I_ I I I I I I U I U 21. i II. S.rateqic...1 25. Henry I. Shaw, et . 41., History of u. S. Marine operaCions in World I war r (5 vols., Washington, DC, 1958-2971); Jeter A. Zsley and Philip A...Combat Troops, Bruce Jacobs, Soldiers (New 3 York, 1958), pp. 169-560; Stouffer, et al., The American Soldier: Combat and Its Afternath (New York, 1965

Reduction of Heavy Metals by Cytochrome c(3)

DOE Office of Scientific and Technical Information (OSTI.GOV)

ABDELOUAS,A.; GONG,W.L.; LUTZE,W.

2000-01-18

We report on reduction and precipitation of Se(VI), Pb(II), CU(II), U(VI), Mo(VI), and Cr(VI) in water by cytochrome c{sub 3} isolated from Desulfomicrobium baczdatum [strain 9974]. The tetraheme protein cytochrome c{sub 3} was reduced by sodium dithionite. Redox reactions were monitored by UV-visible spectroscopy of cytochrome c{sub 3}. Analytical electron microscopy work showed that Se(VI), Pb(II), and CU(II) were reduced to the metallic state, U(W) and Mo(W) to U(IV) and Mo(IV), respectively, and Cr(VI) probably to Cr(III). U(IV) and Mo(W) precipitated as oxides and Cr(III) as an amorphous hydroxide. Cytochrome c{sub 3} was used repeatedly in the same solution withoutmore » loosing its effectiveness. The results suggest usage of cytochrome c{sub 3} to develop innovative and environmentally benign methods to remove heavy metals from waste- and groundwater.« less

U.S. EPA, Pesticide Product Label, , 07/24/1990

EPA Pesticide Factsheets

2011-04-21

... PII'IIlta _ CIIIlta 1Il8I: In. 1I1I1l11eICEIJ: III.' Inl Milia.. II lim .1811 •. ... Ell. • DI ..... 1111 lII.e II Fla. ... aD II-.t fOIn. FII CIIu.:L _let til iECl ... file( IF til EIIII 11M. ...

U.S. EPA, Pesticide Product Label, CRAIN TRIPLE CCC, 03/12/1973

EPA Pesticide Factsheets

2011-04-19

I • For /foSllIl.lb, In,,tllull,.Ii,,, '\\II _II" Ii I" Seh""ls, \\I"lt b, .11111 fI, .1. I" FiJI" us.- 'JI~ 1.;",lIlIt\\\\ '1").:. 11. ',' t·ct SUI't.ll"t o !'-.. Il;! t.11 '.:1,' ! 'I'· bill. ...

U.S. EPA, Pesticide Product Label, , 08/25/1970

EPA Pesticide Factsheets

2011-04-14

... 111( ill.·) IH'!' ;tc-i"" (!"IJt'rI41IfJ~' I'll ':.1 cl"~.~I!" I,r Iwlll:II,,,I,, Ili('" t:,,'1I11 1"';111'11 i';[1 )..:1'11\\1 II "II In';t\\,,d ,,:1 ,lllIlild Ii": i". I·,·d 'I' dain' alii 111;(1, III ...

The Turbulent Boundary Layer on a Rough, Porous Plate: Experimental Heat Transfer with Uniform Blowing

DTIC Science & Technology

1974-05-01

consists of 24 porous plates I!i i forming an eight foot long test section. The individual plates were fabricated by brazing together 50- mil OFlC rcopper...1141 0,444 22 8, V .00071 8244 76941 14,,4614? 1𔃽i1434 U.0041 t.14U 41.8: 77. 11.4)14 U 4 ,,$ d3 901 oU - U111 81019 O227 1 S5330 1, 1589e,6 0,.0 04 1...4i(.HNII:. .4. 10 N. L) MIL DL ’ 1 .414 11 v(JL .1 I-’L? .. / -Ul * H.01 ’ 4 ..llII . 41** ’M Iul’ 4.1 9’MrLHIi’(u.. * IF. , AlIt,, o~i.44I 1OLL.4 1 II

A Dynamic Model of the Initial Spares Support List Development Process

DTIC Science & Technology

1979-06-01

S117Z1NOTE NREI -NOT READI END ITERS IIT7INOTE GPEI -QUANTITY OF PARTS M. END ITER 11775NOTE FUSERF -PARTS USE RATE FACTOR U8WOTE OP U -OTHER PARTS USE...FAILURES ’I 1675R PtJER.L=(NREI.K) (QPEI) (PUSERF.K)+OPUR II7HNOTE PUSER -PARTS USE RATE II7t5NOTE NREI -NOT READY END ITEMS II756NOTE GPEI -QUANTITY

Large-Scale Separation and Wake Closure/Reattachment - The Cascade Problem,

DTIC Science & Technology

1983-05-01

7.3b-d) gives, for all x > xsep K (X) = u(u-l)dy + 1se (11-7.7) 44 UTRC83-13 where Isep is the integrated momentum deficit at separation, from (II...with c1 = (K: o 2/b - Isep /b) positive. So (II-7.5a) requires the underlying form -g ~-1/2_ +- g go (G) + x -1()+..+x 2 (a)+ .... (II-7.10a) for g

New Bedford, Marine And Estuarine Geochemistry - Chapter 7: Partitioning Of Polychlorinated Biphenyls (PCBs) In Marine Sediments, 01-01-1985, SDMS no. 51931

EPA Pesticide Factsheets

2012-04-15

... 1: i:ii:ii'iii!'ini|ii;:i:a|:ih:h: I n, ;, I. 1 l.ul.'Uin cli'j llolii!, Misiiiisini: him in? I: it n II I \\\\A\\\\ Ji'o.ll yi: li:h:u: l.mi!iiil:i!"il hi phnriiy I n '!:'' i'.n ! rani? mini! I'nII. modi! ...

Geochemical controls on microbial nitrate-dependent U(IV) oxidation

USGS Publications Warehouse

Senko, John M.; Suflita, Joseph M.; Krumholz, Lee R.

2005-01-01

After reductive immobilization of uranium, the element may be oxidized and remobilized in the presence of nitrate by the activity of dissimilatory nitrate-reducing bacteria. We examined controls on microbially mediated nitrate-dependent U(IV) oxidation in landfill leachate-impacted subsurface sediments. Nitrate-dependent U(IV)-oxidizing bacteria were at least two orders of magnitude less numerous in these sediments than glucose- or Fe(II)-oxidizing nitrate-reducing bacteria and grew more slowly than the latter organisms, suggesting that U(IV) is ultimately oxidized by Fe(III) produced by nitrate-dependent Fe(II)-oxidizing bacteria or by oxidation of Fe(II) by nitrite that accumulates during organotrophic dissimilatory nitrate reduction. We examined the effect of nitrate and reductant concentration on nitrate-dependent U(IV) oxidation in sediment incubations and used the initial reductive capacity (RDC = [reducing equivalents] - [oxidizing equivalents]) of the incubations as a unified measurement of the nitrate or reductant concentration. When we lowered the RDC with progressively higher nitrate concentrations, we observed a corresponding increase in the extent of U(IV) oxidation, but did not observe this relationship between RDC and U(IV) oxidation rate, especially when RDC > 0, suggesting that nitrate concentration strongly controls the extent, but not the rate of nitrate-dependent U(IV) oxidation. On the other hand, when we raised the RDC in sediment incubations with progressively higher reductant (acetate, sulfide, soluble Fe(II), or FeS) concentrations, we observed progressively lower extents and rates of nitrate-dependent U(IV) oxidation. Acetate was a relatively poor inhibitor of nitrate-dependent U(IV) oxidation, while Fe(II) was the most effective inhibitor. Based on these results, we propose that it may be possible to predict the stability of U(IV) in a bioremediated aquifer based on the geochemical characteristics of that aquifer.

Relationships between biomarkers of cartilage, bone, synovial metabolism and knee pain provide insights into the origins of pain in early knee osteoarthritis.

PubMed

Ishijima, Muneaki; Watari, Taiji; Naito, Kiyohito; Kaneko, Haruka; Futami, Ippei; Yoshimura-Ishida, Kaori; Tomonaga, Akihito; Yamaguchi, Hideyo; Yamamoto, Tetsuro; Nagaoka, Isao; Kurosawa, Hisashi; Poole, Robin A; Kaneko, Kazuo

2011-02-14

We tested the hypothesis that there exist relationships between the onset of early stage radiographically defined knee osteoarthritis (OA), pain and changes in biomarkers of joint metabolism. Using Kellgren-Lawrence (K/L) grading early radiographic knee OA (K/L 2) was detected in 16 of 46 patients. These grades (K/L 1 is no OA and K/L 2 is early OA) were divided into two groups according to the presence or absence of persistent knee pain. Sera (s) and urines (u) were analysed with biomarkers for cartilage collagen cleavage (sC2C and uCTX-II) and synthesis (sCPII), bone resorption (uNTx) and synovitis (hyaluronic acid: sHA). sCPII decreased and sC2C/sCPII, uCTX-II/sCPII and sHA increased with onset of OA (K/L 2 versus K/L 1) irrespective of joint pain. In contrast, sC2C and uCTX-II remained unchanged in early OA patients. Of the patients with K/L grades 1 and 2 sC2C, sCPII, sHA, uNTX and uCTX-II were all significantly increased in patients with knee pain independent of grade. Among the K/L grade 2 subjects, only uCTX-II and uCTX-II/sCPII were increased in those with knee pain. In grade 1 patients both sC2C and sCPII were increased in those with knee pain. No such grade specific changes were seen for the other biomarkers including sHA. These results suggest that changes in cartilage matrix turnover detected by molecular biomarkers may reflect early changes in cartilage structure that account directly or indirectly for knee pain. Also K/L grade 1 patients with knee pain exhibit biomarker features of early OA.

National Synchrotron Light Source II

ScienceCinema

Steve Dierker

2017-12-09

The National Synchrotron Light Source II (NSLS-II) at the U.S. Department of Energy's Brookhaven National Laboratory is a proposed new state-of-the-art medium energy storage ring designed to deliver world-leading brightness and flux with top-off operation

U.S. EPA, Pesticide Product Label, SENVITA SWEET BAR-FLY MIX NO. 133 MEDICATED, 12/27/1972

EPA Pesticide Factsheets

2011-04-21

.• y' " II ... ,. Ii) , : I ; " \\ , ( I " " ! ," I . , l.. _ .... I...t. , " " I" '" 'JI ,j T . , ~ 1,' , ( , I' ,. , , I " \\ I " f II I , , , . " I . I , , , , \\ l 'I " '1 , '., "1 , i ,\\ I , I , . , ". ...

U.S. EPA, Pesticide Product Label, FLIGHT BRAND TOXAPHENE-METHYL PARATHION LV 3.96-0.99, 05/30/1973

EPA Pesticide Factsheets

2011-04-14

• \\ " I II H ) I 1\\ , I) , If{, I \\ II' I \\{ I \\: \\ \\. I! \\ ""Y',I(I\\,, \\: 1'·(1" \\11 (,"iI'" III \\1 "i1'1( '11>1',' ;IIIII\\' I'f)lse."''' SY\\'l'lo'o., \\11 l'II'''i1( 1\\"" ,UI' 1;1, ',. ...

AT2 DS II - Accelerator System Design (Part II) - CCC Video Conference

ScienceCinema

None

2017-12-09

Discussion Session - Accelerator System Design (Part II) Tutors: C. Darve, J. Weisend II, Ph. Lebrun, A. Dabrowski, U. Raich Video Conference with the CERN Control Center. Experts in the field of Accelerator science will be available to answer the students questions. This session will link the CCC and SA (using Codec VC).

Genome-enabled studies of anaerobic, nitrate-dependent iron oxidation in the chemolithoautotrophic bacterium Thiobacillus denitrificans

PubMed Central

Beller, Harry R.; Zhou, Peng; Legler, Tina C.; Chakicherla, Anu; Kane, Staci; Letain, Tracy E.; A. O’Day, Peggy

2013-01-01

Thiobacillus denitrificans is a chemolithoautotrophic bacterium capable of anaerobic, nitrate-dependent U(IV) and Fe(II) oxidation, both of which can strongly influence the long-term efficacy of in situ reductive immobilization of uranium in contaminated aquifers. We previously identified two c-type cytochromes involved in nitrate-dependent U(IV) oxidation in T. denitrificans and hypothesized that c-type cytochromes would also catalyze Fe(II) oxidation, as they have been found to play this role in anaerobic phototrophic Fe(II)-oxidizing bacteria. Here we report on efforts to identify genes associated with nitrate-dependent Fe(II) oxidation, namely (a) whole-genome transcriptional studies [using FeCO3, Fe2+, and U(IV) oxides as electron donors under denitrifying conditions], (b) Fe(II) oxidation assays performed with knockout mutants targeting primarily highly expressed or upregulated c-type cytochromes, and (c) random transposon-mutagenesis studies with screening for Fe(II) oxidation. Assays of mutants for 26 target genes, most of which were c-type cytochromes, indicated that none of the mutants tested were significantly defective in nitrate-dependent Fe(II) oxidation. The non-defective mutants included the c1-cytochrome subunit of the cytochrome bc1 complex (complex III), which has relevance to a previously proposed role for this complex in nitrate-dependent Fe(II) oxidation and to current concepts of reverse electron transfer. A transposon mutant with a disrupted gene associated with NADH:ubiquinone oxidoreductase (complex I) was ~35% defective relative to the wild-type strain; this strain was similarly defective in nitrate reduction with thiosulfate as the electron donor. Overall, our results indicate that nitrate-dependent Fe(II) oxidation in T. denitrificans is not catalyzed by the same c-type cytochromes involved in U(IV) oxidation, nor have other c-type cytochromes yet been implicated in the process. PMID:24065960

76 FR 45715 - Appliance Labeling Rule

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-01

... requirements. Public Law 110-140. EISA amended the Energy Policy and Conservation Act (EPCA) (42 U.S.C. 6291 et... appropriate, a mercury disclosure on the products themselves. \\4\\ 42 U.S.C. 6294(a)(2)(D)(iii)(II)(bb). II... fluorescent [CFL], and LED products). \\7\\ The Commission proposes this expanded coverage pursuant to 42 U.S.C...

U.S. EPA, Pesticide Product Label, ALL SEASON SPRAYABLE WEED & FEED, 10/04/1991

EPA Pesticide Factsheets

2011-04-21

... ltifo ~tdt~U4:tl\\. "tl(, ~(\\t ~lt:p'.\\ nlr~Ltl) to ""II" 1u '11(';,\\ etf' ~ur·t~(f. "'ilter '\\ r,t,.,Stl1t \\.or to I,'t'd1.,O')1 at «.;~ lr I"" Ir,£ I',tan r II/I: If<1ter .:ar ... • ...

Whole blood lead levels are associated with biomarkers of joint tissue metabolism in African American and white men and women: the Johnston County Osteoarthritis Project.

PubMed

Nelson, Amanda E; Chaudhary, Sanjay; Kraus, Virginia B; Fang, Fang; Chen, Jiu-Chiuan; Schwartz, Todd A; Shi, Xiaoyan A; Renner, Jordan B; Stabler, Thomas V; Helmick, Charles G; Caldwell, Kathleen; Poole, A Robin; Jordan, Joanne M

2011-11-01

To examine associations between biomarkers of joint tissue metabolism and whole blood lead (Pb), separately for men and women in an African American and Caucasian population, which may reflect an underlying pathology. Participants in the Johnston County Osteoarthritis Project Metals Exposure Sub-Study (329 men and 342 women) underwent assessment of whole blood Pb and biochemical biomarkers of joint tissue metabolism. Urinary cross-linked N telopeptide of type I collagen (uNTX-I) and C-telopeptide fragments of type II collagen (uCTX-II), serum cleavage neoepitope of type II collagen (C2C), serum type II procollagen synthesis C-propeptide (CPII), and serum hyaluronic acid (HA) were measured using commercially available kits; the ratio of [C2C:CPII] was calculated. Serum cartilage oligomeric matrix protein (COMP) was measured by an in-house assay. Multiple linear regression models were used to examine associations between continuous blood Pb and biomarker outcomes, adjusted for age, race, current smoking status, and body mass index. Results are reported as estimated change in biomarker level for a 5-unit change in Pb level. The median Pb level among men and women was 2.2 and 1.9μg/dL, respectively. Correlations were noted between Pb levels and the biomarkers uNTX-I, uCTX-II, and COMP in women, and between Pb and uCTX-II, COMP, CPII, and the ratio [C2C:CPII] in men. In adjusted models among women, a 5-unit increase in blood Pb level was associated with a 28% increase in uCTX-II and a 45% increase in uNTX-I levels (uCTX-II: 1.28 [95% CI: 1.04-1.58], uNTX-I: 1.45 [95% CI:1.21-1.74]). Among men, levels of Pb and COMP showed a borderline positive association (8% increase in COMP for a 5-unit change in Pb: 1.08 [95% CI: 1.00-1.18]); no other associations were significant after adjustment. Based upon known biomarker origins, the novel associations between blood Pb and biomarkers appear to be primarily reflective of relationships to bone and calcified cartilage turnover among women and cartilage metabolism among men, suggesting a potential gender-specific effect of Pb on joint tissue metabolism that may be relevant to osteoarthritis. Copyright © 2011 Elsevier Inc. All rights reserved.

Whole blood lead levels are associated with biomarkers of joint tissue metabolism in African American and White men and women: The Johnston County Osteoarthritis Project

PubMed Central

Nelson, Amanda E.; Chaudhary, Sanjay; Kraus, Virginia B.; Fang, Fang; Chen, Jiu-Chiuan; Schwartz, Todd A.; Shi, Xiaoyan A.; Renner, Jordan B.; Stabler, Thomas V.; Helmick, Charles G.; Caldwell, Kathleen; Poole, A. Robin; Jordan, Joanne M.

2011-01-01

Purpose To examine associations between biomarkers of joint tissue metabolism and whole blood lead (Pb), separately for men and women in an African American and Caucasian population, which may reflect an underlying pathology. Methods Participants in the Johnston County Osteoarthritis Project Metals Exposure Sub-study (329 men and 342 women) underwent assessment of whole blood Pb and biochemical biomarkers of joint tissue metabolism. Urinary cross-linked N telopeptide of type I collagen (uNTX-I) and C-telopeptide fragments of type II collagen (uCTX-II), and serum cleavage neoepitope of type II collagen (C2C), serum type II procollagen synthesis C-propeptide (CPII), and serum hyaluronic acid (HA) were measured using commercially available kits; the ratio of [C2C:CPII] was calculated. Serum cartilage oligomeric matrix protein (COMP) was measured by an in-house assay. Multiple linear regression models were used to examine associations between continuous blood Pb and biomarker outcomes, adjusted for age, race, current smoking status, and body mass index. Results are reported as estimated change in biomarker level for a 5-unit change in Pb level. Results The median Pb level among men and women was 2.2 and 1.9 µg/dL, respectively. Correlations were noted between Pb levels and the biomarkers uNTX-I, uCTX-II, and COMP in women, and between Pb and uCTX-II, COMP, CPII, and the ratio [C2C:CPII] in men. In adjusted models among women, a 5-unit increase in blood Pb level was associated with a 28% increase in uCTX-II and a 45% increase in uNTX-I levels (uCTX-II: 1.28 [95%CI: 1.04–1.58], uNTX-I: 1.45 [95%CI:1.21–1.74]). Among men, levels of Pb and COMP showed a borderline positive association (8% increase in COMP for a 5-unit change in Pb: 1.08 [95% CI: 1.00–1.18])); no other associations were significant after adjustment. Conclusions Based upon known biomarker origins, the novel associations between blood Pb and biomarkers appear to be primarily reflective of relationships to bone and calcified cartilage turnover among women and cartilage metabolism among men, suggesting a potential gender-specific effect of Pb on joint tissue metabolism that may be relevant to osteoarthritis. PMID:21839992

U.S. EPA, Pesticide Product Label, 2, NITRO-2-ETHYL-1, 3-PROPANEDIOL, 03/19/1969

EPA Pesticide Factsheets

2011-04-13

... ( 1,1,') c.;. II v ,> U .... · 1 jul ey , '. ,J • I'll L 1'1Il i, 'iiJG, SIP, • (lS) J. L. Ril~U:~UIliL't', J. Ot'g. CI,,·iil. g, lH2-U:i'1 (L'j'iu). (L7) V 1 •• 1 . • lJ.:->. J 1 I r <;. ...

Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Jacobus Pharmaceutical Co. Inc. - Level 6 Systems Inc.). Part 11

DTIC Science & Technology

1994-03-01

LL:9 131 -a31 nC I COO.-4 1c4) 000000000000 heGo0(0 -. 100 JO L)O u10 (/.2 - ) _j u 0) I U CIO00-a 111 flnUn ( ( n A A n n(n w 0 (0( 0 4<< 4 04< 04411 0...0 0 0000 .- ~ 0 0 0-440 : N1 coo0 If 0-•I .,o®H. II OOf N HO 4444 4 444 4 OH 100 H N N LA.I 04c1I 100LH 0 0 0 0 0 0 0 0 00 0 C N 1 0 01wL’ULI 0. (n 1...0 03 I • (• I 0 0 00 0 0 00 000000 0 0 0 0 II U..-4(I) 100 00 00le 00 00 000 0000000 00 00 00 00 If I u -4N II N N NN N N NN N INNNN N N N N II I 0

All Prime Contract Awards by State or Country, Place, and Contractor. Part 13 (Allendale, New Jersey -Otero, New Mexico)

DTIC Science & Technology

1990-01-01

N R CA (A CAl (no L4 0 Ij)4Q # j)C U n<U U uM0 ii C-4 ɘ :: 0. H00 .- -Wt .- -()0 M L 1 L -0 nI n L 4( I M 1((0 11 44 4 44 4 44 4 4 z4 4 0) ISO ...0 > ə IMN C13 0t Z 0 044>>~ 0000c 1,41 1IM" Ŗ 1- ) I-- I-- I.- I- U4 Io 14- (I), isL)0z 00 I- ISO ION It -~W ) f z i IION N/ 0A 0 1. 2 0 on 01-- w 0...ZI o M cv ISO . CL ’) C) cn0 000 2>C) 1 0 0 -6 co C1 mI ii 2 W- 0) 0 1-4 0 0404 0 O DU)C> (c In < wi coC’ II La.) Z"I 00 I-I > w o .Joo40 C) loo oo w>0C

U.S. EPA, Pesticide Product Label, , 07/26/1989

EPA Pesticide Factsheets

2011-04-21

... 'I.sb " • .,11, ... Il.".,li, .it. cl •• r MIler f., .t leist 15 1.1111'". I_~iattl, cnhct ,l,.icin. h cu •• , I.,oslin. i_~i.ttl, cnhct ",sieia .... , i .. II,Ui., " .. u It II n"lScin. ...

U.S. EPA, Pesticide Product Label, , 10/01/1982

EPA Pesticide Factsheets

2011-04-14

... 1'11'1' lIlt f')11 .lll· "" . 1, I 1;"' III 1! I' . I I, I 1 II \\ I' IJ\\" i,' I III .\\1 r , 'P i III' II J tit I • J j !nh·,l.'d ).:.' i, 1 i I, I t I nlll, .1' "11, 11 ! i, " '11 I, \\ I II Ii r " ' 1,1, 'i' ", ...

U.S. Marine Corps Study of Establishing Time Criteria for Logistics Tasks

DTIC Science & Technology

2004-09-30

STATISTICS FOR REQUESTS PER DAY FOR TWO BATTALIONS II-25 II-6 SUMMARY STATISTICS IN HOURS FOR RESOURCE REQUIREMENTS PER DAY FOR TWO BATTALIONS II-26 II-7...SUMMARY STATISTICS FOR INDIVIDUALS FOR RESOURCE REQUIREMENTS PER DAY FOR TWO BATTALIONS II-27 Study of Establishing Time Criteria for Logistics...developed and run to provide statistical information for analysis. In Task Four, the study team used Task Three findings to determine data requirements

U.S. EPA, Pesticide Product Label, HAWK T-A 25 MOSQUITO COILS, 10/06/1972

EPA Pesticide Factsheets

2011-04-21

, .', • 1' ••. _. _ .... T?DQ?-\\S) r I I ~ i I i j l \\. - . . II YO ... -- I.... • I .1 '.'\\I"I\\} " f ' .. , . I (. ' " . LI . ~ '" , fj" /' \\ . t\\ 'r; I ' "\\' II 'I . ...• I·~I I ...

Boston Harbor, Massachusetts, Navigation Improvement ...

EPA Pesticide Factsheets

... II Ill II 111 llllll 'l Illlllllll 111 111 i1 l 111' ji' : '.11 T'li "••!! liilli ii fj'!''; 1 '' ,1 , ' "'! f' ,,! I,, - ' il:;, *' i;,'' :s| :, if , i !il SI1 !!';; ij ;„: V*. Nl iilHilii I,1,,,:' K VliU ll ...

Criminal Investigative Activities: World War II and Vietnam Battlefield Implications

DTIC Science & Technology

1988-06-03

WORLD WAR II AND VIET NAM BATTLEFIELD IMPLICATIONS •A thesis presented to the Faculty of the U. S. Army Command and General Staff College in partial...TIME COVERED 114. DATE OF REPORT (Year, Month, Day) 115. PAGE COUNT Master’s Thesis IFROM 8-1&~98 .TO..i-li38I 1988 June 3 I 145 16. SUPPLEMENTARY...CRIMINAL INVESTIGATIVE ACTIVITIES WORLD WAR II AND VIET NAM BATTLEFIELD !MPLICATIONS A thesis presented to the Faculty of the U. S. Army

U.S. EPA, Pesticide Product Label, CHEMMATE - 20S, 03/10/1983

EPA Pesticide Factsheets

2011-04-21

... h .... ;l u· .t,jlj t, J 1, .·,I'r ~" ,!I'ill '. ~" , 1" ~ll:HI~ i 11\\" I • .J hi It ,', ., I Ufo/,·th. n\\\\'d~ u"'J""!" · III:I(.:I,.I(I,il":II'. lL_nl.:II.I,J!lir~;li.d!.' .• J

U.S. EPA, Pesticide Product Label, HELENA AG CHEM TOXAPHENE 6-E AN EMULSIFIABLE LIQUID, 06/14/1983

EPA Pesticide Factsheets

2011-04-14

... '::1. 0 • .:;. U~i'.l:·':.l': v:: ~!.d":.~' Cl.!:;'J:'L.cn J::.i .;\\!l':·.lr·~, P~!l:: flc.1l:!: .,U!·':.C'0, ':c.-.":n:'::.JJll.! Oi';:;0~lSl1 C~::tcr, ,\\tl.lnt.l, Cito.:-1J..l. II I iI ...

[Comparing the anchorage effects of micro-implant and J hook on treating patients with maxillary protrusion].

PubMed

Wu, Xin; Liu, Guo-yuan; Jiang, Yong-lian

2015-10-01

To investigate the differences in anchorage effects between micro-implants and J hook in treating patients with Class II division 1 maxillary protrusion. Thirty-one cases of adult patients with Class II division 1 maxillary protrusion were treated. They were divided into 2 groups depending on their selection. The first group included 17 patients for micro-implant anchorage, who adopted micro-implant and sliding mechanism to close maxillary extraction space and depress the mandibular molar. The second group encompassed 14 cases for J hook, who adopted sliding mechanism, J hooks in high traction and Class II intermaxillary traction to close extraction space. X-ray lateral cephalometric radiographs were measured before and after treatment, and SPSS16.0 software package was employed to compare the differences in soft and hard tissue changes before and after treatment between 2 groups. There were statistically significant differences in SNB, ANB, MP-FH, U1-Y, U6-Y, L6-MP, NLA, and UL-Y between the 2 groups before and after treatment, while there was no significant difference in SNA, U1-SN, U1-X, and U6-X between the 2 groups. In treating patients with Class II division 1 maxillary protrusion, micro-implant has stronger anchorage effects than J hook, while at the same time depressing the mandibular molars, and making it more favorable to improve Class II faces.

NEPSY-II Review: Korkman, M., Kirk, U., & Kemp, S. (2007). "NEPSY--Second Edition" (NEPSY-II). San Antonio, TX: Harcourt Assessment

ERIC Educational Resources Information Center

Davis, John L.; Matthews, Robb N.

2010-01-01

This article presents a review of the "NEPSY-Second Edition" (NEPSY-II), an updated and modified version of the NEPSY (Korkman, Kirk, & Kemp, 1998). The NEPSY-II is an individually administered compendium of tests designed to assess neuropsychological development in children ranging from 3 to 16.11 years old. The authors of the…

Synthesis and Properties of Homonuclear, Dimetallic Nickel(II), Copper(II) and Zinc(II) Complexes of p-Xylenediyl and 2-Butynediyl-Bridged Dicyclens

DTIC Science & Technology

1993-05-01

urease which contains two nickel ions in the active site. Catalytic hydrolysis studies are in progress. 20 DISTRIBUTION /AVAILABILITY OF ABSTRACT 21...for hydrolytic metalloenzymes. In contrast, the enzyme urease has becti show’n tU coftifl two nickel(II) ions in the active site," but as yet the

RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmAII in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithromycin susceptibility.

PubMed

Shoji, Tatsuma; Takaya, Akiko; Sato, Yoshiharu; Kimura, Satoshi; Suzuki, Tsutomu; Yamamoto, Tomoko

2015-10-15

Adenine at position 752 in a loop of helix 35 from positions 745 to 752 in domain II of 23S rRNA is involved in binding to the ribosome of telithromycin (TEL), a member of ketolides. Methylation of guanine at position 748 by the intrinsic methyltransferase RlmA(II) enhances binding of telithromycin (TEL) to A752 in Streptococcus pneumoniae. We have found that another intrinsic methylation of the adjacent uridine at position 747 enhances G748 methylation by RlmA(II), rendering TEL susceptibility. U747 and another nucleotide, U1939, were methylated by the dual-specific methyltransferase RlmCD encoded by SP_1029 in S. pneumoniae. Inactivation of RlmCD reduced N1-methylated level of G748 by RlmA(II) in vivo, leading to TEL resistance when the nucleotide A2058, located in domain V of 23S rRNA, was dimethylated by the dimethyltransferase Erm(B). In vitro methylation of rRNA showed that RlmA(II) activity was significantly enhanced by RlmCD-mediated pre-methylation of 23S rRNA. These results suggest that RlmCD-mediated U747 methylation promotes efficient G748 methylation by RlmA(II), thereby facilitating TEL binding to the ribosome. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

EVALUATION AND INTERPRETATION OF MATERNAL TOXICITY IN SEGMENT II STUDIES: ISSUES, SOME ANSWERS AND DATA NEEDS

EPA Science Inventory

Rogers, J.M., and N. Chernoff. Reproductive Toxicology Division, NHEERL, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, U.S.A. Evaluation and interpretation of maternal toxicity in Segment II studies: Issues, s...

U.S. EPA, Pesticide Product Label, , 09/28/1983

EPA Pesticide Factsheets

2011-04-14

... lind HI"knti,·.,~ l~'\\ &1 Dtpf'mcd. I.,r t1, l'" ,tj .... ,ii{ ... Ul#-'~~U I), CtI.,If ... ~1 c' .... Q. '"fJ 0.''"'1.-(.01,1 .ntcI •• rod#' II(..JI ettec1lwe ';au",,1 SIa;."flo)(oec .. ...

PARIS II: Computer Aided Solvent Design for Pollution Prevention

EPA Science Inventory

This product is a summary of U.S. EPA researchers' work developing the solvent substitution software tool PARIS II (Program for Assisting the Replacement of Industrial Solvents, version 2.0). PARIS II finds less toxic solvents or solvent mixtures to replace more toxic solvents co...

7 CFR 52.1852 - Grades of raisins with seeds-except layer or cluster.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) “U.S. Grade A” is the quality of Raisins with Seeds that have similar varietal characteristics; that... requirements as outlined in Table II of this subpart. (b) “U.S. Grade B” is the quality of Raisins with Seeds... in Table II of this subpart. (c) “U.S. Grade C” is the quality of Raisins with Seeds that have...

NGC 6334 and NGC 6357: Hα kinematics and the nature of the H II regions

NASA Astrophysics Data System (ADS)

Russeil, D.; Tigé, J.; Adami, C.; Anderson, L. D.; Schneider, N.; Zavagno, A.; Samal, M. R.; Amram, P.; Guennou, L.; Le Coarer, E.; Walsh, A.; Longmore, S. N.; Purcell, C.

2016-03-01

Aims: NGC 6334 and NGC 6357 are amongst the most active, optically visible Galactic star-forming complexes. They are composed of several H II regions that have a significant impact on their surrounding. The aim of this paper is to present a kinematic study of the optical H II regions that belong to NGC 6334 and NGC 6357. Methods: We use Fabry-Perot interferometer observations of the Hα line, which cover NGC 6334 and NGC 6357. These observations allow us to analyse the Hα line profiles to probe the kinematics of the ionised gas of both regions. We complement the Hα observations with multi-wavelength data to specify the nature of the H II regions. Results: We determine the dynamical nature of the optical H II regions that belongs to NGC 6334 and NGC 6357. In NGC 6334, GUM 61 is an expanding wind shell-like H II region, GUM 64b exhibits a champagne flow, GM1-24 is the Hα counterpart of two larger regions and H II 351.2+0.5 is, in fact, composed of two H II regions. In NGC 6357, H II 353.08+0.28 and H II 353.09+0.63 are probably stellar wind-shaped bubble H II regions, while H II 353.42+0.45 is a classical photo-ionised H II region. We suggest that, at large scale, star-formation seems to be triggered where large/old H II regions intersect. Inversely, stellar formation seems to have already started in the NGC 6334 north-east filament, irrespective of any evident external H II region impact. While NGC 6357 shows more complicated kinematics, NGC 6334 is characterised by a more active stellar formation. The Hα data (FITS cubes) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/587/A135

Non-enzymatic U(VI) interactions with biogenic mackinawite

NASA Astrophysics Data System (ADS)

Veeramani, H.; Qafoku, N. P.; Kukkadapu, R. K.; Murayama, M.; Hochella, M. F.

2011-12-01

Reductive immobilization of hexavalent uranium [U(VI)] by stimulation of dissimilatory metal and/or sulfate reducing bacteria (DMRB or DSRB) has been extensively researched as a remediation strategy for subsurface U(VI) contamination. These bacteria derive energy by reducing oxidized metals as terminal electron acceptors, often utilizing organic substrates as electron donors. Thus, when evaluating the potential for in-situ uranium remediation in heterogeneous subsurface media, it is important to understand how the presence of alternative electron acceptors such as Fe(III) and sulfate affect U(VI) remediation and the long term behavior and reactivity of reduced uranium. Iron, an abundant subsurface element, represents a substantial sink for electrons from DMRB, and the reduction of Fe(III) leads to the formation of dissolved Fe(II) or to reactive biogenic Fe(II)- and mixed Fe(II)/Fe(III)- mineral phases. Consequently, abiotic U(VI) reduction by reactive forms of biogenic Fe(II) minerals could be a potentially important process for uranium immobilization. In our study, the DMRB Shewanella putrefaciens CN32 was used to synthesize a biogenic Fe(II)-bearing sulfide mineral: mackinawite, that has been characterized by XRD, SEM, HRTEM and Mössbauer spectroscopy. Batch experiments involving treated biogenic mackinawite and uranium (50:1 molar ratio) were carried out at room temperature under strict anoxic conditions. Following complete removal of uranium from solution, the biogenic mackinawite was analyzed by a suite of analytical techniques including XAS, HRTEM and Mössbauer spectroscopy to determine the speciation of uranium and investigate concomitant Fe(II)-phase transformation. Determining the speciation of uranium is critical to success of a remediation strategy. The present work elucidates non-enzymatic/abiotic molecular scale redox interactions between biogenic mackinawite and uranium.

Dissociation of I II in chemical oxygen-iodine lasers: experiment, modeling, and pre-dissociation by electrical discharge

NASA Astrophysics Data System (ADS)

Katz, A.; Waichman, K.; Dahan, Z.; Rybalkin, V.; Barmashenko, B. D.; Rosenwaks, S.

2007-06-01

The dissociation of I II molecules at the optical axis of a supersonic chemical oxygen-iodine laser (COIL) was studied via detailed measurements and three dimensional computational fluid dynamics calculations. Comparing the measurements and the calculations enabled critical examination of previously proposed dissociation mechanisms and suggestion of a mechanism consistent with the experimental and theoretical results obtained in a supersonic COIL for the gain, temperature and I II dissociation fraction at the optical axis. The suggested mechanism combines the recent scheme of Azyazov and Heaven (AIAA J. 44, 1593 (2006)), where I II(A' 3Π 2u), I II(A 3Π 1u) and O II(a1Δ g, v) are significant dissociation intermediates, with the "standard" chain branching mechanism of Heidner et al. (J. Phys. Chem. 87, 2348 (1983)), involving I(2P 1/2) and I II(X1Σ + g, v). In addition, we examined a new method for enhancement of the gain and power in a COIL by applying DC corona/glow discharge in the transonic section of the secondary flow in the supersonic nozzle, dissociating I II prior to its mixing with O II(1Δ). The loss of O II(1Δ) consumed for dissociation was thus reduced and the consequent dissociation rate downstream of the discharge increased, resulting in up to 80% power enhancement. The implication of this method for COILs operating beyond the specific conditions reported here is assessed.

U.S. EPA, Pesticide Product Label, PEARSON'S 10% CHLORDANE, 04/15/1972

EPA Pesticide Factsheets

2011-04-14

\\ \\.1 \\\\'1. i ( ,I (T 1'( )\\'1) .! I , , I. ,. I. il " • 1 ,I t ; r I , , ,\\ . Ii I \\ . , , , II ! : I f , II ;- - . i ,i ,I I •. ( I, I· j • : ! J". ,I.! III ' J , , .,( j \\\\ j. ' .. " 1 J , {' I' . , , , l; i! , I : I, !, ,' f:' ...

U.S. EPA, Pesticide Product Label, PCO LINDANE E-1 INSECTICIDE, 09/21/1983

EPA Pesticide Factsheets

2011-04-13

... lid '",1. Uu (e, .~~ • I"I. ~ii.r in ... ,,1".1'~ ... In "'"uh' .... h._H ... l .... CI • .!!. I .. ,.oCll'. '1. II ,11_ •• , 1.1 ..... 1"".1 "1~~lIh" .., hl"'''5 It hrM'. ...

A Study into Advanced Guidance Laws Using Computational Methods

DTIC Science & Technology

2011-12-01

0; for ii = 2:index integral = integral+(t(ii)-t(ii-1))*u2(ii-1); end J = 20*min(range)^2+integral/1000; 73 outtxt = [’Time (s...0.67*LN; % nose CP XCPW = LN+XW+0.7*CRW-0.2*CTW; % wing CP AN = 0.67*LN*DIAM...0.5*(LENGTH-LN)))/(AN+AB); % body CP %--- Area computations ------------------------------------- SW = 0.5*HW*(CTW+CRW)+CRW*WXT; % wing

U.S. EPA, Pesticide Product Label, PRENTOX SPECIAL AERO-MATIC CONCENTRATE #5, 09/24/1974

EPA Pesticide Factsheets

2011-04-14

,*: ~. I I j i • c {( • ( • I • t t fit t. IC f- , I t .. ( • • t , ( , , • I « { t • • • J-iCilClIl1l JI01l ~l..A1'lII; IS. • • I I f • • • • • II , II • . , , . I • ••• • II'. ...

US (United States) Army Aeromedical Research Laboratory Annual Progress Report, FY 1982.

DTIC Science & Technology

1982-10-01

A’D-li29 854 US(U! TESES ARMY AEROMEDICAL RESEARSH LABORAT ORY 1/2 INNUARGRESS REPORT FY 1982(U RMY NERONEDICRI U Lh RESEARCH4 LAB FORT RUCKER AL...groiath in atl iareas Of suIpport for the 1laborataory , mo Ii of hiich was d iInec tIYnt ie to the mave to the new facilities. Biomedical Engineering ...i L I II 1- C1 : l It0j. I I Office of the Building Engineer ’IA II ’ , the J i rector, I tLS f)iv isi o , SLICC SS CL11 I Il V lez t IA tC Acd CLI

DARPA (Defense Advanced Research Projects Agency) Review on EHF Devices Held in San Diego, California on 24-25 January 1989

DTIC Science & Technology

1989-04-01

representing the official policies , either expressed or implied, of the Naval Ocean Systems Center or the U.S. Government. * I I NAVAL OCEAN SYSTEMS CENTER San...0 00 NNNc~ ___CI rI CncD I S zo I II C CC II I II....118 Iz oj z I. w z I w 0 z E 04 ww In jl ~ 11 u -i00 z~zo> Lu 0 F-J LL >- cr 0 - 0- M F-J CL z

The Optimal Allocation of Army Enlistment Incentives by MOS; Analyses of CY 86-87 Experience, Impacts of Nonmonetary Guidance Counselor Incentives, and PC Software

DTIC Science & Technology

1989-05-01

0 ELECTE VARSHA P. RAO SEP11190 AND U DONNA ROBERTS MAY 1989 APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED O Research & Studies Division U.S...DAKF 15-87-0-0144 Subcontract Sub-Hi 88-12, Do No. 88-007, with the Research and Studies Division, Program Analysis and Evaluation Directorate of...Toomepuu, Chief, Research and Studies Division, for their helpful counsel. ii TABLE OF CONTENTS PAGE DISCLAIMER ii ACKNOWLEDGMENTS ii LIST OF FIGURES v

Gender affects renal vasoconstrictor response to Ang I and Ang II.

PubMed

Gandhi, S K; Gainer, J; King, D; Brown, N J

1998-01-01

This study tested the hypothesis that gender affects the pressor and renal vasoconstrictor responses to angiotensin (Ang) I and Ang II in salt-replete normotensive subjects. Ang I and Ang II were infused in graded doses into 9 men and 8 women in a randomized, single-blind, crossover study. There were no differences between genders in baseline blood pressure, heart rate, sodium excretion, renal plasma flow, angiotensin-converting enzyme (ACE) genotype, ACE activity, plasma renin activity, aldosterone, or Ang II levels. Although pressor responses to Ang I and Ang II were similar in men and women, there was a negative relationship between the change in mean arterial pressure and the change in heart rate during Ang I and II infusion in women only. The half-time of the pressor response after discontinuation of Ang I but not Ang II infusion was greater in men than in women (9.5+/-2.2 versus 4.3+/-2.1 minutes, P<.05). This difference in duration did not result from gender differences in the metabolism of Ang I because Ang II levels measured during Ang I infusion were identical in men and women. In contrast, the renal vasoconstrictor response to Ang I and Ang II was significantly increased in women compared with that in men (Ang I, -243+/-31 versus -138+/-13 U/1.73 m2; Ang II, -233+/-25 versus -175+/-18 U/1.73 m2; P<.03). These data suggest an effect of gender on baroreflex reactivity during angiotensin infusion. Moreover, in the setting of similar Ang II concentrations, the dramatic difference in the renal vasoconstrictor responses to Ang I and Ang II between salt-replete men and salt-replete women suggests gender differences at a pharmacodynamic level.

The ERK pathway regulates Na(+)-HCO(3)(-) cotransport activity in adult rat cardiomyocytes.

PubMed

Baetz, Delphine; Haworth, Robert S; Avkiran, Metin; Feuvray, Danielle

2002-11-01

The sarcolemmal Na(+)-HCO cotransporter (NBC) is stimulated by intracellular acidification and acts as an acid extruder. We examined the role of the ERK pathway of the MAPK cascade as a potential mediator of NBC activation by intracellular acidification in the presence and absence of angiotensin II (ANG II) in adult rat ventricular myocytes. Intracellular pH (pH(i)) was recorded with the use of seminaphthorhodafluor-1. The NH method was used to induce an intracellular acid load. NBC activation was significantly decreased with the ERK inhibitors PD-98059 and U-0126. NBC activity after acidification was increased in the presence of ANG II (pH(i) range of 6.75-7.00). ANG II plus PD-123319 (AT(2) antagonist) still increased NBC activity, whereas ANG II plus losartan (AT(1) antagonist) did not affect it. ERK phosphorylation (measured by immunoblot analysis) during intracellular acidification was increased by ANG II, an effect that was abolished by losartan and U-0126. In conclusion, the MAPK(ERK)-dependent pathway facilitates the rate of pH(i) recovery from acid load through NBC activity and is involved in the AT(1) receptor-mediated stimulation of such activity by ANG II.

76 FR 13432 - In the Matter of Certain Display Devices, Including Digital Televisions and Monitors II; Notice...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-11

... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-765] In the Matter of Certain Display Devices, Including Digital Televisions and Monitors II; Notice of Investigation AGENCY: U.S. International Trade... that a complaint was filed with the U.S. International Trade Commission on February 9, 2011, under...

U.S. EPA, Pesticide Product Label, PCNB SOIL & TURF LIQUID DRENCH, 06/02/1986

EPA Pesticide Factsheets

2011-04-14

... 1"., t. III ., •• Ieal , ... rI,u .... , II ruso"'1J fit' fir til. ,"', 1111. II til. ... III llllluilJ f.fIo 11l1li1110 1101 allllflClIllf lid/if 1lIIar, "' 'Iller .IIU." til rlllt fll 81 allCll .... '

The Credibility of the Supply Department in the Maintenance Environment.

DTIC Science & Technology

1987-12-01

0 0 0 GROUPS A A L P S S A F S A A U U V L H N C B R I -’:.T F .4- [ ~SOAFL I __ I.........1___I __ __ _ _ [ SOASH ____fl II _I ii [ SOLANT WI! I t U...of afloat and ashore commands within the surface community SO All Supply Corps officer respondents SOAFL Supply Corps officers of afloat commands SOASH

An Analysis of the Effects on the Proposed Coast Guard User Fee on the Oceangoing U.S. Merchant Marine.

DTIC Science & Technology

1982-06-01

exports . Merchant shipbuilding, as well as trade, flourished in the colonial period. Rich natural resources, human talent, 20 ION and the ability to...of all U.S. import and export trade was carried in American vessels. During the following years, the U.S. Merchant Marine growth suf- fered from the...II II..... In 1843, U.S. exports exceeded imports for the first time in U.S. history and the launching of the first clipper ship, RAINBOW, signaled

Anthropometric Survey of U.S. Army Personnel: Pilot Summary Statistics, 1988

DTIC Science & Technology

1991-07-01

VETA I -0.04 KUPTSIS--- VETA II 4.12 KJ•0IS-- VETA II 2.72 SNUMBER OF SUBJECTS 334 NUMBER OF SUBJECTS 487 PERCENTIIES PERCENTILES E ..T..ETERS INCHES...I 0.09 SYMMEIRY- VETA I 0.28 KUWIS- VEIA II 2.73 NJRtOIS- VETIA II 2.96 NUMBER OF SUBJECirS 334 NUMB OF SUBJECTS 487 PERCENTIIES PFRCENfILES EN E ...COEFF. OF VARIAT.ON 5.9% S2lMEIRY- VETA I 0.48 S’ - E Y- VETA I 0.11 KURIOSIS--vTA II 3.77 IVIWIS-VEMA II 2.86 NUMBER OF SUBJECIS 334 NUMBER OF SUBJECI

12 CFR 218.722 - Exemption allowing banks to calculate trust and fiduciary compensation on a bank-wide basis.

Code of Federal Regulations, 2010 CFR

2010-01-01

...)(I)) to the extent that it effects transactions in securities for any account in a trustee or...)), including the advertising restrictions in section 3(a)(4)(B)(ii)(II) of the Act (15 U.S.C. 78c(a)(4)(B)(ii...

U.S. EPA, Pesticide Product Label, GABRIEL METHOXYCHLOR TECHNICAL, 06/20/1968

EPA Pesticide Factsheets

2011-04-21

• !IJ!I!II!II!!w.n'~ - .. II'I'!!1'I!:'IRI'''lIIJI'I'!!III.-:._!!lI!!III'l:I!l'!~.WiIll:!'l')l:;s;~~-ttt!:'!' a'!?!~_''''-m2&~-.t ;!I"""€&'!"'i~ .,!" 1-tt"lfl'J,:r"!'rL'n'!I-fu,!!!,dfj4!":!; ...

U.S. EPA, Pesticide Product Label, HILO DIP FOR CATS, 03/02/1989

EPA Pesticide Factsheets

2011-04-14

... ITI'! h' '/'" f··\\ HeTE Ch"·:~'t·" HI 1..1., 11!~1' ,.,; J! .. :. 1" I:) -":l' '" I~· :1." ::-L.:br.-.lll"" \\. ,orJ'! ... "I (' I r ::, II ," .• . hi II' 1;:!J I I\\' I II - ll) .... I' I ,I r \\' • • • ...

U.S. EPA, Pesticide Product Label, GARRATT-CALLAHAN FORMULA 315, 09/08/1989

EPA Pesticide Factsheets

2011-04-21

... 'Up.it II II , Sillt.,~ 1 .. ,,,11 • • r " .t'tf ,rluhttS .",.·d 1:1, shh Ifl' hul .. tt..tltus h..STI( COIT.IIDS T'I,h tlUt

U.S. EPA, Pesticide Product Label, PARATHION EHTYL-METHYL 6-3, 04/21/1972

EPA Pesticide Factsheets

2011-04-21

... ', .. , nIl I' ~~nh~Ii". " .. 1'1. II'" 'flO: T,,, .. fiji[ 10':;\\1';' ""t' I I rAe 1/"'.I ~t~'. ~ ,Nl .. l' .. : Uf.p ... t •• , • 1"" .1('" I.·, l""'iM".'" "r,_ I., .,"II,d, .11'1'1, I,,,.! ...

Zircon from charnockite gneiss, charnockite, and leucosome of migmatite in the Nimnyr Block of the Aldan Shield

NASA Astrophysics Data System (ADS)

Glebovitsky, V. A.; Sedova, I. S.; Berezhnaya, N. G.; Skublov, S. G.; Samorukova, L. M.

2015-12-01

The microgeochemistry of zircon was studied in three samples: charnockite gneiss (1594), charnockite (1594a), and migmatite leucosome Lc4 (1594c). Prismatic (Zrn I) and oval (Zrn II) zircon morphotypes are distinguished in the first two samples. Most zircon grains consist of two-phase cores and overgrowth rims variable in thickness. The average weighted concordant U-Pb age of Zrn II cores from charnockite gneiss is 2436 ± 10 Ma. The concordant ages of Zrn I and Zrn II cores from charnockite are 2402 ± 16 Ma and 2453 ± 14 Ma, respectively. Some overgrowth rims are 1.9-2.1 Ga in age. In leucosome Lc4, all measured prismatic zircon crystals yielded a discordant age of 1942 ± 11 Ma (the upper intersection of discordia with concordia). These zircons are strongly altered and anomalously enriched in U and Th. Zrn I grains are enriched relative to Zrn II in REE, Li, Ca, Sr, Ba, Hf, Th, and U. Zrn I is considered to be a product of melt crystallization or subsolidus recrystallization in the presence of melt. Zrn II is relict or crystallizing from melt and then partly fused again. Zrn I from charnockite gneiss and especially from charnockite are markedly altered and have a more discordant age than Zrn II. This is probably related to concentration of fluid in the residual melt left after zircon crystallization.

U.S. EPA, Pesticide Product Label, BONIDE MOLETOX II POISON BAIT, 05/21/1981

EPA Pesticide Factsheets

2011-04-13

... ',1 t,) (,I PI,j ;'II tJ :!- fl1 •. - C\\ (j L~I fl) rii ::j :<:: 1ft: -11""1 •. "U 2:(") n ""\\rd .. ;0 0' Lsd (:':'j L/ '" » g c: ~-l -o 2 :;0 /fY'lI ):;:. n :c'Jr: ~ ~ C"":ll 5~ ~~ ~ ~ d ...

U.S. EPA, Pesticides, Label, MAQUAT 2420-CITRUS, 12/16/2010

EPA Pesticide Factsheets

2011-04-13

... 8. i[(AJresh{scjltlti.6:n:··mbst;,~~:prepa.~~d)!(p,repareia;fre~h;i?Q!uJi..QQ)]· atiIEt~§@~II~:orwJ:i~D lLJ~t~J;()II;J!iql'lib~..f~rtf ... 9r trigg~r:~PI~y.~~e:\\fic .. ...

75 FR 41889 - In the Matter of Certain Collaborative System Products and Components Thereof (II); Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-19

... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-728] In the Matter of Certain Collaborative System Products and Components Thereof (II); Notice of Investigation AGENCY: U.S. International Trade Commission... complaint was filed with the U.S. International Trade Commission on June 15, 2010, under section 337 of the...

Geographic List of Prime Contract Awards. Oct 1992-Sep 1993. FY 1993. (Aberdeen, Washington-Laramie, Wyoming). Part 13

DTIC Science & Technology

1994-03-01

If LiOm iI NNNY - -" N-I CV II Li000 II ==Z z m W LsJ COZ Z he co 2E Z NZ 11 -4 1LiON, 1 ~ u- -4 NN NN- YŘ Nm -4 NNi N- -4 N~ N 11 w I Ui00 to 1 NN 2c...cm cj W Of CY C-j m cj 2c w x CY ;c (m cj N 11 U01n It 13 13 13 -3 ŗ 13 If U01W 11 n m m z m z M it LIOM 11 < < < 1:10 if f (.)ON 110" 0 Q to Q ca 0

Fish debris record the hydrothermal activity in the Atlantis II deep sediments (Red Sea)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oudin, E.; Cocherie, A.

1988-01-01

The REE and U, Th, Zr, Hf, Sc have been analyzed in samples from Atlantis II and Shaban/Jean Charcot Deeps in the Red Sea. The high Zr/Hf ratio in some sediments indicates the presence of fish debris or of finely crystallized apatite. The positive ..sigma..REE vs P/sub 2/O/sub 5/ and ..sigma..REE vs Zr/Hf correlations show that fish debris and finely crystallized apatite are the main REE sink in Atlantis II Deep sediments as in other marine environments. The hydrothermal sediments and the fish debris concentrates have similar REE patterns, characterized by a LREE enrichment and a large positive Eu anomaly.more » This REE pattern is also observed in E.P.R. hydrothermal solutions. Fish debris from marine environments acquire their REE content and signature mostly from sea water during early diagenesis. The hydrothermal REE signature of Atlantis II Deep fish debris indicate that they probably record the REE signature of their hydrothermal sedimentation and diagenetic environment. The different REE signatures of the Shaban/Jean Charcot and Atlantis II Deep hydrothermal sediments suggest a sea water-dominated brine in the Shaban/Jean Charcot Deep as opposed to the predominantly hydrothermal brine in Atlantis II Deep. Atlantis II Deep fish debris are also characterized by their high U but low Th contents. Their low Th contents probably reflect the low Th content of the various possible sources (sea water, brine, sediments). Their U contents are probably controlled by the redox conditions of sedimentation.« less

Impact of Battalion and Smaller African-American Combat Units on Integration of the U.S. Army in the European Theater of Operations During World War II

DTIC Science & Technology

2015-06-12

WORLD WAR II A thesis presented to the Faculty of the U.S. Army Command and General Staff College in partial fulfillment of the requirements...other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a ...combat units fought in World War II, and this is a small pool of veterans to gather information on their achievements during a normal human life span

Nursing Care Hour Standards Study. Part 1. Section B. Patient Classification System Model Development

DTIC Science & Technology

1981-09-01

Measurement/Adult El FI~ [El 1:11] II PIES Form 326e (OT) 1 Novembeti 1978 A-3 sfti= 237 Saline IrrigatioD (Gastric)W uli il 111 Enema: Cleansing Mi...U lIED Dilatation and -Curettage/Assisting Physician ii) El Do~ EI M.1 L or Evacuation Vaginal /Pelvic Examinrations/Assisting Physician ElU L. IE l2...ADMINISTRATION: Oral -QB E ED EE ElE Suppositories Rectal/ Vaginal 1E El El El I ElD Topical MI~II iE Sublingual III ol El El El DIAGNOSTIC TESTS: Bone

[Assessment of high sensitivity C-reactive protein (HS-CRP) as a marker of liver inflammation in patients with metabolic syndrome].

PubMed

Rodríguez-Leal, Gustavo Arturo; Morán, Segundo; Gallardo, Irazu; Milke, Pilar; Guevara-González, Luis

2006-01-01

C-reactive protein (CRP) plays an important role on inflammatory processes associated to the metabolic syndrome (MS), alike of insulin sensitivity, endothelial dysfunction and fibrinolysis insufficiency. Alanine aminotransferase (ALT) may be a sensible marker for the diagnosis of hepatic damage and has therefore been used as an alternative method for the noninvasive diagnosis of non-alcoholic fatty liver disease (NAFLD), especially in epidemiological studies. At the present time, the possible utility of high sensitivity CRP (hsCRP) as a simple measure to detect the degree of hepatic inflammatory response during the development NAFLD in MS has not been explored. To evaluate the measurement of serologic hsCRP for the identification of hepatic inflammatory response in patients with MS. Seven hundred and forty persons (526 men and 214 women), mean age 45 +/- 11 years who were asymptomatic and otherwise seeming healthy in whom a medical questionnaire was applied underwent physical examination, laboratory testing, hepatic ultrasound and measurement of hsCRP by the immuno-turbidimetric method. Receiver operating characteristic (ROC) analysis was used to evaluate the sensitivity and specificity of all possible hsCRP for detecting different degrees of hepatic inflammation (ALT > 44 U/L and ALT > 88 U/L). Patients were stratified according to the presence of metabolic syndrome (MS) and ALT concentration in three groups: Group I, having MS and ALT > 44 U/L (n = 39); Group II, having ALT > 44 U/L without MS (n = 105) and Group III, having ALT < or = 44 U/L without MS (n = 596). The optimal hsCRP cut-off for detecting patients with ALT 44 U/L was 2.5 mg/L (sensibility 66%; specificity 50%) and for detecting patients with ALT > 88 U/L was 2.35 (sensibility 72%; specificity 59%). hsCRP serum concentrations in Group I were significantly higher than in Group II and Group III (p < 0.05) but no difference was found between Group II and Group III (Group I = 6.0 +/- 6.7 mg/L vs. Group II = 2.8 +/- 3.1 mg/L, vs. Group III = 2.9 +/- 4.1 mg/L). ALT concentrations were also significantly higher in Group I than in Group II and Group III, (p < 0.05) and a difference between Group II and Group III (p < 0.05) was also found (Group I = 72 +/- 31 U/L vs. Group II = 64 +/- 29 U/L vs. Group III = 24 +/- 8 U/L). These results suggest that the measurement of hsCRP for the identification of hepatic inflammatory response in patients with MS with NAFLD is limited because of its low sensibility and specificity observed on identifying different degrees of hepatic inflammation.

Effects of inverting contour and features on processing for static and dynamic face perception: an MEG study.

PubMed

Miki, Kensaku; Takeshima, Yasuyuki; Watanabe, Shoko; Honda, Yukiko; Kakigi, Ryusuke

2011-04-06

We investigated the effects of inverting facial contour (hair and chin) and features (eyes, nose and mouth) on processing for static and dynamic face perception using magnetoencephalography (MEG). We used apparent motion, in which the first stimulus (S1) was replaced by a second stimulus (S2) with no interstimulus interval and subjects perceived visual motion, and presented three conditions as follows: (1) U&U: Upright contour and Upright features, (2) U&I: Upright contour and Inverted features, and (3) I&I: Inverted contour and Inverted features. In static face perception (S1 onset), the peak latency of the fusiform area's activity, which was related to static face perception, was significantly longer for U&I and I&I than for U&U in the right hemisphere and for U&I than for U&U and I&I in the left. In dynamic face perception (S2 onset), the strength (moment) of the occipitotemporal area's activity, which was related to dynamic face perception, was significantly larger for I&I than for U&U and U&I in the right hemisphere, but not the left. These results can be summarized as follows: (1) in static face perception, the activity of the right fusiform area was more affected by the inversion of features while that of the left fusiform area was more affected by the disruption of the spatial relation between the contour and features, and (2) in dynamic face perception, the activity of the right occipitotemporal area was affected by the inversion of the facial contour. Copyright © 2011 Elsevier B.V. All rights reserved.

U.S. EPA, Pesticide Product Label, CSA DOG AND CAT REPELLENT AEROSOL SPRAY, 03/31/1993

EPA Pesticide Factsheets

2011-04-14

... II il I ,illi.1 .1 re'er.1 II. I. lie Itil ,IO'act il • 111~el i.-.lliliell .itt ita I.telill. ~ rr .. ... latri'l .r ,llIliti. lelt Itt elletl .1 I.is ,r.'ltl t, lirll Ire.lil, • 11111 htlll,ltlOll Iftl. ...

40 CFR 82.24 - Recordkeeping and reporting requirements for class II controlled substances.

Code of Federal Regulations, 2011 CFR

2011-07-01

... transformation; (v) The date on which the class II controlled substances were imported; (vi) The port of entry.... Customs entry form; (xiv) Dated records documenting the sale or transfer of class II controlled substances... source facility; (vii) The U.S. port of entry for the import, the expected date of shipment and the...

40 CFR 82.24 - Recordkeeping and reporting requirements for class II controlled substances.

Code of Federal Regulations, 2014 CFR

2014-07-01

... transformation; (v) The date on which the class II controlled substances were imported; (vi) The port of entry.... Customs entry form; (xiv) Dated records documenting the sale or transfer of class II controlled substances... source facility; (vii) The U.S. port of entry for the import, the expected date of shipment and the...

U.S. EPA, Pesticide Product Label, GRANOL PLUS FLOWABLE INSECT. AND FUNG. CEREAL SEED TRT., 07/31/1992

EPA Pesticide Factsheets

2011-04-21

... ( f ••••• trat~ Itt. k _ial. De .. te .. ... Iuti.,. lII .. t st_ actsS trfttH sttds WtW ,.Iuti., Ii ... Nttt To Ustrl Sttd cII.rdilll1T trftttd wi" tkis ""Itt lISt Itt _'-t,IY dYtd iii .. ...

Superpowers Influence in the Horn of Africa

DTIC Science & Technology

1989-05-19

Greenfield: In its extent, its government and its problems, present day Ethiopia is largely the creaLion of the Emperor Menelik II . The process dating...conflict or cooperation between those involved during the next ten to fifteen years or so. 4 U / .- ii TABLE OF CONTENTS Page ABSTRACT... ii CHAPTER I. INTRODUCTION ..... ................. . . Survey of the Literature ..... ........... 3 Objective of the

Intraosseous Hydroxocobalamin in the Treatment of Acute, Severe Cyanide Induced Cardiotoxicity in a Swine (Sus Scrofa) Model - An Alternate Administration Route for Chemical Mass Casualties

DTIC Science & Technology

2012-04-05

Ut:IVI:I... I 11:111VI:> Hydroxocobalamin, hypotension, cyanide, poisoning , intraosseous, Vitamin B 12a, Vitamin B 12 I 1:). :>CI...U I111 T L.L~:>:>II...34II...A I IUIII Ul": I I. LIIVIII ~II UN Ur- I 0. IIIUIVItl1:11 I ::1a . 1\\I~ IVI I: ur- 111:.:>t’UN:>It:ILC 1ŕ:11:>UN II. 111:1"UI1 I D.Ati:>II1~L.I c

RESIS-II: An Updated Version of the Original Reservoir Sedimentation Survey Information System (RESIS) Database

USGS Publications Warehouse

Ackerman, Katherine V.; Mixon, David M.; Sundquist, Eric T.; Stallard, Robert F.; Schwarz, Gregory E.; Stewart, David W.

2009-01-01

The Reservoir Sedimentation Survey Information System (RESIS) database, originally compiled by the Soil Conservation Service (now the Natural Resources Conservation Service) in collaboration with the Texas Agricultural Experiment Station, is the most comprehensive compilation of data from reservoir sedimentation surveys throughout the conterminous United States (U.S.). The database is a cumulative historical archive that includes data from as early as 1755 and as late as 1993. The 1,823 reservoirs included in the database range in size from farm ponds to the largest U.S. reservoirs (such as Lake Mead). Results from 6,617 bathymetric surveys are available in the database. This Data Series provides an improved version of the original RESIS database, termed RESIS-II, and a report describing RESIS-II. The RESIS-II relational database is stored in Microsoft Access and includes more precise location coordinates for most of the reservoirs than the original database but excludes information on reservoir ownership. RESIS-II is anticipated to be a template for further improvements in the database.

Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients

PubMed Central

Fu, Tao; Liu, Yanliang; Li, Kai; Wan, Weiwei; Pappou, Emmanouil P.; Iacobuzio-Donahue, Christine A.; Kerner, Zachary; Baylin, Stephen B.; Wolfgang, Christopher L.; Ahuja, Nita

2016-01-01

We previously developed a novel tumor subtype classification model for duodenal adenocarcinomas based on a combination of the CpG island methylator phenotype (CIMP) and MLH1 methylation status. Here, we tested the prognostic value of this model in stage II colorectal cancer (CRC) patients. Tumors were assigned to CIMP+/MLH1-unmethylated (MLH1-U), CIMP+/MLH1-methylated (MLH1-M), CIMP−/MLH1-U, or CIMP−/MLH1-M groups. Age, tumor location, lymphovascular invasion, and mucin production differed among the four patient subgroups, and CIMP+/MLH1-U tumors were more likely to have lymphovascular invasion and mucin production. Kaplan-Meier analyses revealed differences in both disease-free survival (DFS) and overall survival (OS) among the four groups. In a multivariate analysis, CIMP/MLH1 methylation status was predictive of both DFS and OS, and DFS and OS were shortest in CIMP+/MLH1-U stage II CRC patients. These results suggest that tumor subtype classification based on the combination of CIMP and MLH1 methylation status is informative in stage II CRC patients, and that CIMP+/MLH1-U tumors exhibit aggressive features and are associated with poor clinical outcomes. PMID:27880934

Tumors with unmethylated MLH1 and the CpG island methylator phenotype are associated with a poor prognosis in stage II colorectal cancer patients.

PubMed

Fu, Tao; Liu, Yanliang; Li, Kai; Wan, Weiwei; Pappou, Emmanouil P; Iacobuzio-Donahue, Christine A; Kerner, Zachary; Baylin, Stephen B; Wolfgang, Christopher L; Ahuja, Nita

2016-12-27

We previously developed a novel tumor subtype classification model for duodenal adenocarcinomas based on a combination of the CpG island methylator phenotype (CIMP) and MLH1 methylation status. Here, we tested the prognostic value of this model in stage II colorectal cancer (CRC) patients. Tumors were assigned to CIMP+/MLH1-unmethylated (MLH1-U), CIMP+/MLH1-methylated (MLH1-M), CIMP-/MLH1-U, or CIMP-/MLH1-M groups. Age, tumor location, lymphovascular invasion, and mucin production differed among the four patient subgroups, and CIMP+/MLH1-U tumors were more likely to have lymphovascular invasion and mucin production. Kaplan-Meier analyses revealed differences in both disease-free survival (DFS) and overall survival (OS) among the four groups. In a multivariate analysis, CIMP/MLH1 methylation status was predictive of both DFS and OS, and DFS and OS were shortest in CIMP+/MLH1-U stage II CRC patients. These results suggest that tumor subtype classification based on the combination of CIMP and MLH1 methylation status is informative in stage II CRC patients, and that CIMP+/MLH1-U tumors exhibit aggressive features and are associated with poor clinical outcomes.

Investigating the Incorporation of Personality Constructs into IMPRINT

DTIC Science & Technology

2009-02-01

early in the system acquisition process. The U.S. Navy took the lead by developing the HARDMAN Comparability Methodology (HCM) to analyze the trade...space between hardware and manpower. Subsequently, the U.S. Army then adapted HCM, renamed HARDMAN I to include a broader range of weapon systems. A...subsequent evolution by the U.S. Army automated the process and was called HARDMAN II. In the mid to late 1980s HARDMAN II evolved, linking MPT to

U.S. EPA, Pesticide Product Label, , 01/30/1990

EPA Pesticide Factsheets

2011-04-14

... c·d l'l'I,IIc-at Ion If) II(lor aU11 hll~I' Itu;, .. d::. Hllrll)' I"r"!il,'cI IUI'"I'nrc ulld Hlurt'd d,01hlnl;, SIIfllY IlIfN'tI)' Into crll(~ks, I: I II!'I' I !' anti Inf,'··dl,,1 "P'1I5 fI ...

U.S. EPA, Pesticide Product Label, , 09/10/1982

EPA Pesticide Factsheets

2011-04-21

... h·fort'.1 I~, 1!:i Int:hi!~ Ii qh U,. fli11I,'/':H (i1o','I() lilt· t.". I l,t"·,1·>I(\\(; ,1/ 1',,', 1'JJ(Jh <;tat,e'i Rctlu. ,. S[)I.lY dl'" 11) kPI'p'''q ,t·,-I" I\\. 'II' . If ,11 "I,f ij, !,,. ...

8 CFR 499.1 - Prescribed forms.

Code of Federal Regulations, 2011 CFR

2011-01-01

... shown or a subsequent edition date. Form No. Edition date Title and description M-288 12-30-87 United States History 1600-1987, Level II. M-289 12-31-87 United States History 1600-1987, Level I. M-290 01-01-90 U.S. Government Structure, Level II. M-291 12-31-87 U.S. Government Structure, Level I. M-302 03...

8 CFR 499.1 - Prescribed forms.

Code of Federal Regulations, 2010 CFR

2010-01-01

... shown or a subsequent edition date. Form No. Edition date Title and description M-288 12-30-87 United States History 1600-1987, Level II. M-289 12-31-87 United States History 1600-1987, Level I. M-290 01-01-90 U.S. Government Structure, Level II. M-291 12-31-87 U.S. Government Structure, Level I. M-302 03...

U.S. EPA, Pesticide Product Label, BEST WEED & FEED 10-6-4 FERTILIZERS KILLS WEEDS, 10/30/1972

EPA Pesticide Factsheets

2011-04-14

(""1"""; • I. t \\, •. j}l".-;JIi':!l,,'('llt ('PI!'rr\\l'~~'. Con tl 1(";1 lIll! J,. t"..'11 j 'u:y ; / ' I (" • " . r"" "; r,.. II ! II ' 'Bk L J :,: I' / ' !'j . / .. 1 IjJl.i'~.i· 1.1: ~!:;I)l~:;rl':;: • ...

Reactivity of Uranium and Ferrous Iron with Natural Iron Oxyhydroxides.

PubMed

Stewart, Brandy D; Cismasu, A Cristina; Williams, Kenneth H; Peyton, Brent M; Nico, Peter S

2015-09-01

Determining key reaction pathways involving uranium and iron oxyhydroxides under oxic and anoxic conditions is essential for understanding uranium mobility as well as other iron oxyhydroxide mediated processes, particularly near redox boundaries where redox conditions change rapidly in time and space. Here we examine the reactivity of a ferrihydrite-rich sediment from a surface seep adjacent to a redox boundary at the Rifle, Colorado field site. Iron(II)-sediment incubation experiments indicate that the natural ferrihydrite fraction of the sediment is not susceptible to reductive transformation under conditions that trigger significant mineralogical transformations of synthetic ferrihydrite. No measurable Fe(II)-promoted transformation was observed when the Rifle sediment was exposed to 30 mM Fe(II) for up to 2 weeks. Incubation of the Rifle sediment with 3 mM Fe(II) and 0.2 mM U(VI) for 15 days shows no measurable incorporation of U(VI) into the mineral structure or reduction of U(VI) to U(IV). Results indicate a significantly decreased reactivity of naturally occurring Fe oxyhydroxides as compared to synthetic minerals, likely due to the association of impurities (e.g., Si, organic matter), with implications for the mobility and bioavailability of uranium and other associated species in field environments.

The Importance of the United States Security Assistance Program for Somalia’s National Security

DTIC Science & Technology

1990-02-01

NUMBERS Carlisle Barracks, PA 17013 II . CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE 1 February 1990 Same 13. NUMBER OF PAGES 14. MONITORING AGENCY...So it is a cycle--no aid, the Somali army grows weaker, the Somalian ii *ieeie& get more boll. the enemies e,:ourage ir.Lrser.: in--urgeraie3 cause...APPENDIX II - SOMALI HISTORY ..... .............. II -i iv INTRODUCT ION Tli_ paper will introduce the origins and development of U. S. sEiurity

Final report on testing of TOPAZ II unit Ya-21u: Output power characteristics and system capabilities

NASA Astrophysics Data System (ADS)

Luchau, David W.; Sinkevich, Valery G.; Wernsman, Bernard; Mulder, Daniel M.

1996-03-01

A final report on the output power characteristics and capabilities of the TOPAZ II Space Nuclear Power Unit Ya-21u is presented. Results showed that after a total of almost 8,000 hours of system testing in the U.S. and Russia, several emergency cooldowns, and three inadvertent air introductions to the interelectrode gap (IEG) that the TOPAZ II demonstrates the potential for providing reliable power in a space environment. Output power optimizations and system characteristics following a shock and vibration test are shown. These tests were performed using electrical heaters that simulate nuclear fuel heating. This paper will focus primarily on the changes in output power characteristics over the lifetime of Ya-21u. All U.S. testing was conducted at the Thermionic System Evaluation Test (TSET) Facility of the New Mexico Engineering Research Institute (NMERI) as a part of the TOPAZ International Program (TIP). TIP is managed by the Air Force Phillips Laboratory (PL) for the Ballistic Missile Defense Organization (BMDO).

Listening to Mothers II: Report of the Second National U.S. Survey of Women's Childbearing Experiences

PubMed Central

Declercq, Eugene R.; Sakala, Carol; Corry, Maureen P.; Applebaum, Sandra

2007-01-01

With permission from Childbirth Connection, the “Executive Summary” for the Listening to Mothers II survey is reprinted, here. The landmark Listening to Mothers I report, published in 2002, described the first national U.S. survey of women's maternity experiences. It offered an unprecedented opportunity to understand attitudes, feelings, knowledge, use of obstetric practices, outcomes, and other dimensions of the maternity experience. Listening to Mothers II, a national survey of U.S. women who gave birth in 2005 that was published in 2006, continues to break new ground. Although continuing to document many core items measured in the first survey, the second survey includes much new content, exploring earlier topics in greater depth, as well as some new and timely topics. PMID:18769512

76 FR 81005 - International Security Advisory Board (ISAB) Meeting Notice; Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-27

.... For more information, contact Richard W. Hartman II, Executive Director of the International Security..., 2011. Richard W. Hartman II, Executive Director, International Security Advisory Board, U.S. Department...

76 FR 58076 - International Security Advisory Board (ISAB) Meeting Notice; Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-19

... information, contact Richard W. Hartman II, Executive Director of the International Security Advisory Board..., 2011. Richard W. Hartman II, Executive Director, International Security Advisory Board, U.S. Department...

Organizational Diagnosis: A Review and a Proposed Method

DTIC Science & Technology

1974-09-01

r IL YC I . I I I.j .. L 0 ie k.. LJt’IJ1, I C 10 k II I 63 , IIV. II I7 L ls L If e L-ue .J *7 C I 64 F2 C .1 F1 .1I 2Is 30a nI j1 ,33...L,. Ii 68 V.p In I? W.’ 1rvI ý I 4 VIi . 1 U.1,.1o. vi le . r : Wi It IC Lt’ ’ ofI -!Z 0’ c .. *’ .fNNN" f.,(4%ZI0CN Ii VI %j I Z.Z U, IJ 4-I4-. e A c ...FZ4WW4 i ,. e . I. 4:. Il L Ir -7, e %nI: I -IL, I r ,I . c ’ ’D

Effects of an inhibitor of tripeptidyl peptidase II (Ala-Ala-Phe-chloromethylketone) and its combination with an inhibitor of the chymotrypsin-like activity of the proteasome (PSI) on apoptosis, cell cycle and proteasome activity in U937 cells.

PubMed

Bury, M; Młynarczuk, I; Pleban, E; Hoser, G; Kawiak, J; Wójcik, C

2001-01-01

AAF-AMC is not a specific TPP II substrate, since it is also hydrolyzed by purified proteasomes. Moreover, AAF-cmk, claimed to be a specific TPP II inhibitor, also inhibits the chymotrypsin-like activity of the proteasome. While AAF-cmk itself is mildly cytostatic to U-937 cells and induces cell cycle block in G1, its combination with PSI does not induce an increase in the cytostatic/cytotoxic effects. This suggests that TPP II is possibly less important for cell metabolism than it was previously believed and it is less probable that it can be able to fully compensate for the loss of the proteasome function.

Literature and History--A Focus on the Era of the Great Depression and World War II (1929-1945).

ERIC Educational Resources Information Center

Ahern, John; Sandmann, Alexa

1997-01-01

Provides an annotated bibliography and suggested teaching activities for units on the Great Depression and World War II. The materials support inquiry into the causes of the Great Depression and World War II and how these events transformed U.S. society. The annotated bibliography includes novels, memoirs, biographies, and political studies. (MJP)

Superfund Record Of Decision United Creosoting TX Second ...

EPA Pesticide Factsheets

... ak, • > a— k. — — at • • 3 tl Q,«w ^» II u 7 M — —• tl •»- i. a ii v. • o *.» . ~ O TJ « • -— • tl M M • ca • 4- • — M 3 • II • a) C HO — , V b, j; QOM ' wi ti - kf ...

U.S. Department of Defense Official Website - World War II Memorial

Science.gov Websites

- The newly opened World War II Memorial on the National Mall in Washington, D.C., was dedicated May 29 . It honors the 16 million who served in the armed forces of the United States during World War II, the ;greatest generation." Defense Department photo illustration by Navy Lt. Cmdr. Jane Campbell World War

On Achieving Network LPI (Link Parameter Interactions) for Spread Spectrum Communications.

DTIC Science & Technology

1985-10-01

Direct Sequence,Longley-Rice Model, Adaptive Control, LPI, Scenario Snapshots,Interference Limi ted , Wi deband Propagation Modell1ing. . i idL COU This...0; a. ..- ,2 w N a11 N z , <:X --. t ,0 II fr Zo 7 10m I II P:3 ZZXUO. (3O U 𔃻. 0 WUN 4 - 0 4,U w 0-N~lrC~C (fjwW -w 2 -. OI- C) I- I Li tjU (A xf

The Relativistic Solar Proton Event of 11 June 1991

DTIC Science & Technology

1993-01-01

A D-A 78 6 2 ATON ~ t ~e~~orForm Approved ""MB No 0, ,0188 u~ii..iuuum ii~uu u~i o zj r~1 cmments rojaraing’ -ts ouc~er *ýtjm.,te )-, ther 3ýo’ ) s...8217L1G..4f~i ,,4eC~ j . rt ’Cr ntorr-jriop6#norr jE tr~ 4Orq , ?left~f ,n IIIIIIIIIIII| |I I II ~~e-Gr .... ýC •O . ....... Ŕ .... %8...Apatity, Russia and Mawson , Antarctica recorded an - 7 percent increase while stations viewing in the probable "reverse" direction such as Tixie Bay

Forced Draft Blowers, Duct Work For

DTIC Science & Technology

1935-06-01

il l~!! · ;Jp iiH X j H ~ rt ’l ~t;Jn; J!1 ’’ild .at~ rfl: 1:;!( ~rLtf {: PJ : tf1 :~ff:’n’’ !lh1~rt ~1~ · ., , •.. ’ , l,l·,tr t’t’t,m,;l ~ ·rr. I I...Jii ~ ~ ~~~~·htt tt ill· IQ\\u ·· ~t ~ lrt 111 t{~ ifub!ilL 0ii :trtW!,ff.’ : · tj tf1 -l-!1 ’ ·• ll·ld~Htf ’II ’t 1 lrl lll ld u [ 1 · ~ :,· l~ltl

Joint Services Highway Shock Index Project

DTIC Science & Technology

1975-06-01

V (4 > t-t t-t » a> « a u >s 0 H (* M 4J <> % nt u a H pg 3 bo (3) 33M0J iOVdNI 30 i ^tiM*ft*Btlff? niif ^*^^ 9 TABLE IX VERTICAL IMPACT...DISTRIBUTION 40 46 60 73 I UST OF ILLUSTRATIONS Figure 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Truck Type I...Oie-Half Load, Truck Type II . Static Test, Three-Eighths Load, Truck Type II Static Test, One-Fourth Load, Truck Type II Page 5 6 6 8 9

Anaerobic Nitrate-Dependent Metal Bio-Oxidation

NASA Astrophysics Data System (ADS)

Weber, K.; Knox, T.; Achenbach, L. A.; Coates, J. D.

2007-12-01

Direct biological oxidation of reduced metals (Fe(II) and U(IV)) coupled to nitrate reduction at circumneutral pH under anaerobic conditions has been recognized in several environments as well as pure culture. Several phylogentically diverse mesophilic bacteria have been described as capable of anaerobic, nitrate-dependent Fe(II) oxidation (NFOx). Our recent identification of a freshwater mesophilic, lithoautotroph, Ferrutens nitratireducens strain 2002, capable of growth through NFOx presents an opportunity to further study metal bio- oxidation. Continuing physiological studies revealed that in addition to Fe(II) oxidation, strain 2002 is capable of oxidizing U(IV) (4 μM) in washed cell suspensions with nitrate serving as the electron acceptor. Pasteurized cultures exhibited abiotic oxidation of 2 μM U(IV). Under growth conditions, strain 2002 catalyzed the oxidation of 12 μM U(IV) within a two week period. Cultures amended with sodium azide, an electron transport inhibitor, demonstrated limited oxidation (7 μM) similar to pasteurized cultures, supporting the direct role of electron transport in U(IV) bio-oxidation. The oxidation of U(IV) coupled denitrification at circumneutral pH would yield enough energy to support anaerobic microbial growth (ΔG°'= -460.36 kJ/mole). It is currently unknown whether or not strain 2002 can couple this metabolism to growth. The growth of F. nitratireducens strain 2002 utilizing Fe(II) as the sole electron donor was previously demonstrated. The amount of U(IV) (~12 μM) that strain 2002 oxidized under similar autotrophic growth conditions yields 0.0019 kJ, enough energy for the generation of ATP (5.3 x 10-20 kJ ATP-1), but not enough energy for cell replication as calculated for nitrate-dependent Fe(II) oxidizing conditions (0.096 kJ) assuming a similar metabolism. In addition to F. nitratireducens strain 2002, a nitrate-dependent Fe(II) oxidizing bacterium isolated from U contaminated groundwater, Diaphorobacter sp. strain TPSY, was also capable of nitrate- dependent U(IV) oxidation (8 μM over 24 hours, pseudo first order rate constant of 0.12 ± 0.02 hr-1) in washed cell suspensions. Further biochemical investigation of nitrate-dependent U(IV) oxidation in strain TPSY revealed the expression of several putative high molecular weight proteins specific to this metabolism. Together with the previously described metabolic ability of Geobacter metallireducens (Finneran et al. 2002) and Thiobacillus denitrificans (Beller 2005), these data indicate that anaerobic, metal oxidation may be a ubiquitous microbial metabolism.

2,6-Diiminopiperidin-1-ol: an overlooked motif relevant to uranyl and transition metal binding on poly(amidoxime) adsorbents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kennedy, Zachary C.; Cardenas, Allan Jay P.; Corbey, Jordan F.

2016-01-01

Glutardiamidoxime, a structural motif on sorbents used in uranium extraction from seawater, was discovered to cyclize in situ at room temperature to 2,6-diimino-piperidin-1-ol in the presence of uranyl nitrate. The new diimino motif was also generated when exposed to competing transition metals Cu(II) and Ni(II). Multinuclear μ-O bridged U(VI), Cu(II), and Ni(II) complexes featuring bound diimino ligands were isolated. A Cu(II) complex with the historically relevant cyclic imide dioxime motif is also reported for structural comparison to the reported diimino complexes.

77 FR 19642 - Low Enriched Uranium From France: Final Results of Antidumping Duty Changed Circumstances Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-02

... in U.S. customs territory, and (ii) are re-exported within eighteen (18) months of entry of the LEU... amend the scope of the order and to extend the deadline for the re-exportation of this sole LEU entry... transporter(s) while in U.S. customs territory, and (ii) are re-exported within eighteen (18) months of entry...

40 CFR 2.301 - Special rules governing certain information obtained under the Clean Air Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the Act (except a provision of Part II of the Act with respect to a manufacturer of new motor vehicles or new motor vehicle engines); (ii) Provided or obtained under section 208 of the Act, 42 U.S.C. 7542... of papers, books, or documents issued under the authority of section 307(a) of the Act, 42 U.S.C...

International Student Access to U.S. Higher Education since World War II: How NAFSA (Association of International Educators) Has Influenced Federal Policy

ERIC Educational Resources Information Center

Miyokawa, Norifumi

2009-01-01

This dissertation is a study of the policy process behind the legislation and regulation governing international student access to U.S. higher education since the immediate aftermath of World War II. The particular research focus of this dissertation is on NAFSA: Association of International Educators (originally established as the National…

Powers of Persuasion--Poster Art of World War II. Teaching with Documents.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

Guns, tanks, and bombs were the principal weapons of World War II, but there were other, more subtle forms of warfare. Words, posters, and films waged a constant battle for the hearts and minds of the U.S. citizenry as military weapons engaged the enemy. Persuading the U.S. public became a wartime industry, almost as important as the manufacturing…

7 CFR 51.1995 - U.S. No. 1.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) Blanks; and, (ii) Broken or split shells. (4) Free from damage caused by: (i) Stains; and, (ii) Adhering... accordance with one of the size classifications in Table I. Table I Size classifications Maximum size—Will...

7 CFR 51.1995 - U.S. No. 1.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) Blanks; and, (ii) Broken or split shells. (4) Free from damage caused by: (i) Stains; and, (ii) Adhering... accordance with one of the size classifications in Table I. Table I Size classifications Maximum size—Will...

7 CFR 3560.57 - Designated places for section 515 housing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... on: (i) The incidence of poverty, (ii) The existence of substandard housing, (iii) The lack of... designated place for processing. (ii) A previously funded Agency, the U.S. Department of Housing and Urban...

Terminal Area Forecasts, Fiscal Years 1981-1992,

DTIC Science & Technology

1981-02-01

4 51 181 191 REAICN-STATE: AGL-IL LOCID: SOl NONTOWERED CITY: STERLING ROCKFALLS AIRPORT: hIdITESIOE CO ARPT-JOS H 8ITTORF BASED AIRCRAFT: 51 I...T AL 1119 4 0 U U Li Li u U .3 a 0 u + 1AIN , .1 U 4 ii 4 U U L 0 Gi I 0 31 181 . 3 a a a 4 U 0 0 U 6 2 33 19) J a u a 0 a J a 0 0 33 J9 u u u u 0 1 0...3 12 31 1 48 14 2 17 64 38 192 Il A1 11 305 j Ii 3. 1 50 15 l 17 66 39 LaNtLNTS: ESIsNAIt AlA TAXI LOAD FAITUK. Rt ,3UM-N1ATEI A.S3-NS LUCIUSl GI

Revised Height/Weight Sizing Programs for Men’s Protective Flight Garments

DTIC Science & Technology

1979-04-01

V 0 4 HHH HHH H-HT rIrIr- - -4 NN 04i$ 04 - 𔃾 E-’ 0)4 Hl m II I III I IlI I II k 0 [ xl :Iz U() -4C , C) 0>’D) C, 000 000 000 0 0 1" (0C N2 0 04 CN... xl - to 0 ajg ). 14P)f 4 m i-j C oP) t 0 t 0-. N aa H H N 00 Lii <- V) .4 Z. aI- : LI- N , . W. Wl 0 ŕ mI C CD0z IL C wA0ICO ~ ~ ~ ~ J toA C ~C o N to...LiL U)- 0 x4 9 0) I Lu WI c.o~ to~0. 04 1-- 0 U)M*gtov 0II to 40t 0II- .4 Xl ; *0N4 IL oWES MC c I-- w ( 0 lot 3. "I LL I Xwl 0 " LL4 N 1- 1 04 N 140 w

Advanced Concepts of Naval Engineering Maintenance Training. Volume 2. Appendix F

DTIC Science & Technology

1976-05-01

maintenance instruction, the Hagan Automatic Boiler Control (ABC) course. These job requirements also included the tasks, skills, and knowledges for all...Pressure 1 3/4 NAVTRAEQÜIPCEN 74-C-0151-1 TABLE OF CONTENTS VOLUME II OF II APPENDIX F Page Hagan Automatic Boiler Controls Systems (FAS) 6...a c a ■* w ■H u 0 M « s? u ’• B n J-riH 3 o c 0 hhO a a o -i •H -I 0 -H 9J ■ a a oi « C -a u <rl « vi) •a - 8 ai >> u u

Early headgear effect on the eruption pattern of maxillary second molars.

PubMed

Abed, Yossi; Brin, Ilana

2010-07-01

To test the hypothesis that the use of a combination headgear (HG) during the first phase of orthodontic treatment has no effect on the eruption pattern of the maxillary second permanent molars. The records of the patients in a two-phase randomized clinical trial of early Class II treatment were utilized. The HG group comprised 47 patients, and the control (CON) group comprised 52 patients. The mean age of both groups was 9.4 years at the beginning of the clinical trial (T1). Cephalograms and panoramic views obtained at T1 and at the end of 15 months of phase I treatment or observation (T2) were utilized. The vertical and horizontal movements of the first and second upper molars (U6 and U7, respectively) were measured. The beginning of phase II (T3) and the end of phase II (T4) records were visually reviewed for follow-up of the eruption of the U7. The pattern of movement for the distal and vertical displacement of the U6 and U7 was significantly different in the HG and CON groups (P < .001). At the end of phase I, none of the U7 in either group were diagnosed as malposed or suspected for impaction. At the end of phase II, all but one U7 with a possible cystic lesion had erupted. The hypothesis is rejected. Forces exerted by combination headgear to the U6 in phase I have a distalizing effect and a transitory slowing down effect on the eruption of the U7 buds. These latter teeth always erupted except when pathology occurred.

76 FR 17781 - Guidance Under Section 1502; Amendment of Matching Rule for Certain Gains on Member Stock...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... for part 1 continues to read in part as follows: Authority: 26 U.S.C. 7805. * * * 0 Par. 2. Section 1.1502-13 is amended by revising paragraphs (c)(6)(ii)(C)(2) and (c)(6)(ii)(D)(1) to read as follows: Sec. 1.1502-13 Intercompany transactions. * * * * * (c) * * * (6) * * * (ii) * * * (C) * * * (2) Effect...

Correspondence Concerning Women and the Army Air Forces in World War II. Teaching with Documents.

ERIC Educational Resources Information Center

Schamel, Wynell B.; Blondo, Richard A.

1994-01-01

Contends that, although the role of women in the U.S. military and on the homefront during World War II has received increased attention, the service of the civilian women pilots has not been adequately recognized. Presents a classroom lesson on the origins and work of the Women Airforce Service Pilots (WASP's) during World War II. (CFR)

School Library Resources, Textbooks, and Other Instructional Materials: Title II, ESEA. Annual Report, 1973.

ERIC Educational Resources Information Center

Office of Education (DHEW), Washington, DC.

Based on the narrative reports submitted to the U.S. Office of Education, this annual report describes the operation of the Elementary and Secondary Education Act Title II Program (ESEA Title II) in FY 1973 in the 50 states, the District of Columbia, Puerto Rico, the Virgin Islands, American Samoa, Guam, the Trust Territory of the Pacific Islands,…

School Library Resources, Textbooks, and Other Instructional Materials: Title II, ESEA. Annual Report, 1971.

ERIC Educational Resources Information Center

Office of Education (DHEW), Washington, DC.

Based on the financial and narrative reports submitted by the States and other areas to the U.S. Office of Education, this annual report describes the operation of the Elementary and Secondary Education Act Title II Program (ESEA Title II) in FY 1971 in the 50 states, the District of Columbia, Puerto Rico, the Virgin Islands, American Samoa, Guam,…

Automotive Stirling engine development program

NASA Technical Reports Server (NTRS)

Farrell, R.; Hindes, C.; Battista, R.; Connelly, M.; Cronin, M.; Howarth, R.; Donahue, A.; Slate, E.; Stotts, R.; Lacy, R.

1988-01-01

The study of high power kinematic Stirling engines for transportation use, testing of Mod I and Mod II Stirling engines, and component development activities are summarized. Mod II development testing was performed to complete the development of the basic engine and begin characterization of performance. Mod I engines were used for Mod II component development and to obtain independent party (U.S. Air Force) evaluation of Stirling engine vehicle performance.

Ocean Simulation Model for Internal Waves

DTIC Science & Technology

1990-08-01

MODEL1.DAT U D 4°NZ Real U,V,W, (U(i),V(i),W(i), Z Z(i), i= 1 ,NZ) MODEL1.AUX U S 3°NZ Real NT,NX,NZ,DT, NTNX,NZDT, DXDZ,T0, LAT , DX,DZ,T0, LAT , LON,AZ LON...Oceanographic and Atmospheric Research Laboratory, Stennis Space Center, Mississippi 39529-5004. 9 1 .... .... . .. ...8 I I I II I I Foreword The effects of the...I A. Background 1 B. Project Objectives 1 C. Purpose of This Manual 1 II. Background and Derivation of Algorithms 2 A. Stochastic Representation of

SRDS Technical Program Document, Fiscal Year 1982 Research and Development Approved Projects.

DTIC Science & Technology

1982-01-01

U.JIORF NUfl.Pj: 202-u26-9240 QFS ;AF-20/FE32 AGAFF £NT5;rf.E PUI).EiIJE’ TTCVlM CFA.II~ i AQFLFA FRvT jFl~ii: U GINIZATICN NAKE .: AGRFFEMT RUBBER~ F:’.A...D.EVELOPMENTS AND ENHANCEMENTS. THIS SYSTEM PERFORMANCE DATA WELL 𔃺NTRIBUTE TO THE INFORIMATION CUR!RENTLY AVAILABLE FOE NAKING DECISIONS TO IMPLEMENT...Z.cTSS/AP.TF ITIA IPE INTEGRATIONI ANAL Rp COPPLAEYE - 6/81 ~U N FINAL :,ITE -ANAL REPORT COMPL_( TEEN SEC I. SPACING) 11/81 ATMR FINAL FURCTIOFAL

Aircraft Crash Survival Design Guide. Volume I. Design Criteria and Checklists. Revision

DTIC Science & Technology

1980-12-01

5.7.2 Types of Systems . . . . . . . .. . 98 5.7.3 General Design Criteria .............. 106 5.7.4 Webbing and Attachments ........... ... 113 5.7.5...EO 00 1 2w 4 H Ix Q 4) C 9 4) I ( DH 4 U >1 040 ~V M 𔃺 4J 4)0 -,4U𔃾 U 0,.,q -- a Le Wx-i )U 4J EUq 0 -.4 (D 0󈧰-U CO .4 (4 U 0 41~ 4-4-4 V41 402 0 0...in lightweight systems. Experience has shown that it is 106 S fl lilii1i:I i~i] -l .-r- "----’.----’----- ..--.. .... 350 max Shoulder harness fitting

All Prime Contract Awards by State or Country, Place and Contractor. Part 23. (Greenland-Kuwait)

DTIC Science & Technology

1989-01-01

0 (I-I Ix EIc eIN II 01o (- <-4INIjr- mooc )OO- 00 w00 I- I ) Io (,N aI 02 0)) M INI04 OOO 0 000 >z o0 2 IX E I CIN 4I00 0 -4-000000 0 00aC n < (A...ZZZ l~z "ZZZZ -,ZZZZZZZZ22ZZZZZZZZZ 07):IIUIcO) z 2 2 z 22 2 zz 222 zzzzzzzzz2zzzzzzz2 cc 142 II I I)if I mooc In W’ (0 ) ~f0 W4 -4 W N(14(W - -4 In W...D 0 a C -I In Ln In In U) in In Lo In In In I-I r- 00 (D (D 1-1 -4 r- !, U.) 0) Cl) X In 1 11 aoa(= C> MOOC 0000OO013 mocoo x Q C> O " r- < C𔃾 I M

Electrochemical Detection of Transient Cobalt Hydride Intermediates of Electrocatalytic Hydrogen Production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiedner, Eric S.; Bullock, R. Morris

2016-07-06

We report the use of variable scan rate cyclic voltammetry to detect transient CoIIIH and CoIIH intermediates of electrocatalytic H2 production by CoII(dmgBF2)2(CH3CN)2 and [CoII(PtBu2NPh2)(CH3CN)3]2+. In both cases, reduction of the CoIIIH intermediate was observed to coincide with the CoII/I couple, and the resulting CoIIH intermediate is protonated by acid to afford H2. Our studies indicate that in electrocatalytic H2 production, protonation of CoIIH is rate-limiting for CoII(dmgBF2)2(CH3CN)2, and protonation of CoI is rate-limiting for [CoII(PtBu2NPh2)(CH3CN)3]2+. This research was supported as part of the Center for Molecular Electrocatalysis, an Energy Frontier Research Center funded by the U.S. Department of Energy,more » Office of Science, Office of Basic Energy Sciences. Pacific Northwest National Laboratory is operated by Battelle for the U.S. Department of Energy.« less

SALT long-slit spectroscopy of LBQS 2113-4538: variability of the Mg II and Fe II component

NASA Astrophysics Data System (ADS)

Hryniewicz, K.; Czerny, B.; Pych, W.; Udalski, A.; Krupa, M.; Świȩtoń, A.; Kaluzny, J.

2014-02-01

Context. The Mg II line is of extreme importance in intermediate redshift quasars since it allows us to measure the black hole mass in these sources and to use these sources as probes of the distribution of dark energy in the Universe, as a complementary tool to SN Ia. Aims: Reliable use of Mg II requires a good understanding of all the systematic effects involved in the measurement of the line properties, including the contamination by Fe II UV emission. Methods: We performed three spectroscopic observations of a quasar LBQS 2113-4538 (z = 0.956) with the SALT telescope, separated in time by several months and we analyze in detail the mean spectrum and the variability in the spectral shape. Results: We show that even in our good-quality spectra the Mg II doublet is well fit by a single Lorentzian shape. We tested several models of the Fe II pseudo-continuum and showed that one of them well represents all the data. The amplitudes of both components vary in time, but the shapes do not change significantly. The measured line width of LBQS 2113-4538 identifies this object as a class A quasar. The upper limit of 3% for the contribution of the narrow line region (NLR) to Mg II may suggest that the separation of the broad line region and NLR disappears in this class of objects. Based on observations made with the Southern African Large Telescope (SALT) under program 2012-1-POL-008 (PI: Czerny).Fe II template shown in Fig. 8 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/562/A34

The Indigenous and Exogenous Aspects of Moral Education: A Comparative Analysis of the U.S. Military Occupation in Japan and Germany after World War II.

ERIC Educational Resources Information Center

Shibata, Masako

During the U.S. military occupation of Japan after World War II, few sectors of Japanese society were left untouched. Reforms during the occupation included education, religion, moral values, and gender relations. By contrast, in Germany, except in the Soviet-controlled zone, no radical changes were introduced in the education system during the…

Seasheds, a Sealift Enhancement Feature: An Analysis of Methods Employed for Lifting DoD’s Outsize Cargo

DTIC Science & Technology

1993-09-23

do not get called into government service. (Ackley, 1992) 51 1. The Transportation Problems Associated with Soasheds Commercial U.S.-flag liner trade...II! I .F-- I - T i• "* Holds 1, 2, 6, & 7 for 20’ contalners only 94 Class: CG-S-6$C C Number of Soasheds : 12u ber of CCSA: 6 Hold I Held 2: II

Prediction of Supersonic Store Separation Characteristics Including Fuselage and Stores of Noncircular Cross Section, Volume IV. Appendices C and D, Details of Program II.

DTIC Science & Technology

1980-11-01

act in the sense displayed in Figure 17 of Volume II. All moments are about the store moment center COMMON /ONE/ DELTP(250),FN(250), PNLC (250),SWPPLE...linear loading pressure coefficient of Jth u-velocity panel FN(J) normal force divided by q for Jth u-velocity panel PNLC (J) panel chord through control

38 CFR 3.43 - Burial benefits at the full-dollar rate for certain Filipino veterans residing in the United...

Code of Federal Regulations, 2014 CFR

2014-07-01

.... citizenship through birth in the territorial U.S., birth abroad as provided under title 8, United States Code.... passport; (ii) A birth certificate showing that he or she was born in the U.S.; or (iii) A Report of Birth...) Property tax bills and receipts; and (F) School records. (ii) A Post Office box mailing address in the...

38 CFR 3.43 - Burial benefits at the full-dollar rate for certain Filipino veterans residing in the United...

Code of Federal Regulations, 2011 CFR

2011-07-01

.... citizenship through birth in the territorial U.S., birth abroad as provided under title 8, United States Code.... passport; (ii) A birth certificate showing that he or she was born in the U.S.; or (iii) A Report of Birth...) Property tax bills and receipts; and (F) School records. (ii) A Post Office box mailing address in the...

38 CFR 3.43 - Burial benefits at the full-dollar rate for certain Filipino veterans residing in the United...

Code of Federal Regulations, 2013 CFR

2013-07-01

.... citizenship through birth in the territorial U.S., birth abroad as provided under title 8, United States Code.... passport; (ii) A birth certificate showing that he or she was born in the U.S.; or (iii) A Report of Birth...) Property tax bills and receipts; and (F) School records. (ii) A Post Office box mailing address in the...

38 CFR 3.43 - Burial benefits at the full-dollar rate for certain Filipino veterans residing in the United...

Code of Federal Regulations, 2010 CFR

2010-07-01

.... citizenship through birth in the territorial U.S., birth abroad as provided under title 8, United States Code.... passport; (ii) A birth certificate showing that he or she was born in the U.S.; or (iii) A Report of Birth...) Property tax bills and receipts; and (F) School records. (ii) A Post Office box mailing address in the...

38 CFR 3.43 - Burial benefits at the full-dollar rate for certain Filipino veterans residing in the United...

Code of Federal Regulations, 2012 CFR

2012-07-01

.... citizenship through birth in the territorial U.S., birth abroad as provided under title 8, United States Code.... passport; (ii) A birth certificate showing that he or she was born in the U.S.; or (iii) A Report of Birth...) Property tax bills and receipts; and (F) School records. (ii) A Post Office box mailing address in the...

Experimental and density functional theory (DFT) studies on the interactions of Ru(II) polypyridyl complexes with the RAN triplex poly(U)˙poly(A)*poly(U).

PubMed

Zhang, Hong; Liu, Xuewen; He, Xiaojun; Liu, Ying; Tan, Lifeng

2014-11-01

There is renewed interest in investigating triple helices because these novel structures have been implicated as a possible means of controlling cellular processes by endogenous or exogenous mechanisms. Due to the Hoogsteen base pairing, triple helices are, however, thermodynamically less stable than the corresponding duplexes. The poor stability of triple helices limits their practical applications under physiological conditions. In contrast to DNA triple helices, small molecules stabilizing RNA triple helices at present are less well established. Furthermore, most of these studies are limited to organic compounds and, to a far lesser extent, to metal complexes. In this work, two Ru(II) complexes, [Ru(bpy)2(btip)](2+) (Ru1) and [Ru(phen)2(btip)](2+) (Ru2), have been synthesized and characterized. The binding properties of the two metal complexes with the triple RNA poly(U)˙poly(A)*poly(U) were studied by various biophysical and density functional theory methods. The main results obtained here suggest that the slight binding difference in Ru1 and Ru2 may be attributed to the planarity of the intercalative ligand and the LUMO level of Ru(II) complexes. This study further advances our knowledge on the triplex RNA-binding by metal complexes, particularly Ru(II) complexes.

76 FR 51400 - Importer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... narcotic raw material are not appropriate. DEA has considered the factors in 21 U.S.C. 823(a) and 952(a... classes of controlled substances: Drug Schedule Raw Opium (9600) II Concentrate of Poppy Straw II (9670...

45 CFR 1385.8 - Formula for determining allotments.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... Department of Commerce, for the three most recent consecutive years for which satisfactory data are available...)(B)(ii) of the Social Security Act), (42 U.S.C. 402(d)(1)(B)(ii)). [49 FR 11777, Mar. 27, 1984, as...

The Effects of 6-Month Chronic Low Level Inhalation Exposures to Hydrazine on Animals

DTIC Science & Technology

1974-12-01

L ’. Milia , "OanoLr(>;j.cnL’si Pnlmnnaic Ja IJrazina Solfatd in IV^pi I i.’inminc HAI .15, c.’ Lav. Isi. Anal. L’niv...CD 00 o C=5 o REPORT DOCUMENTATION PAGE III pirt. uH i’-i" i’.’ :i:r^ici : u- ■.:i; l i • A’-r ..sp iC’.’ .■/.•;acril iv.:.’ ir...ii ;. ;;j.-r.:i./r’/, t’\\!r-.,::;Kicij i Di -;’* :;i!j’-r 1;/’M ; Unclcis:-,i;’ii-ii ; ’ . , ft j’.’’ I ’J * ’I •»*

U.S.-China Strategic Dialogue, Phase II

DTIC Science & Technology

2007-04-12

Chinese Presentation 12:00-1:30p Lunch – Hibiscus Suite (Kalia Tower-2nd floor) 1:30p Panel II: Crisis Escalation in Theory and History Paper...Lunch Hibiscus Suite (Kalia Tower-2nd floor) 1:30p Panel IV: Nuclear Weapons Safety and Security: Comparing national approaches and discussing... Hibiscus Suite (Kalia Tower-2nd floor) 25 APPENDIX II: CONFERENCE PARTICIPANTS 26 China Rear Admiral Yang Yi Director Institute of

Synthesis of New Five Coordinated Copper(II) and Nickel(II) Complexes of L-Valine and Kinetic Study of Copper(II) with Calf Thymus DNA

PubMed Central

Tak, Aijaz Ahmad; Arjmand, Farukh

2002-01-01

Five coordinated novel complexes of Cu II and Ni II have been synthesized from benzil and 1,3- diaminopropane- Cu II / Ni II complex and characterized by elemental analysis, i.r., n.m.r., e.p.r, molar conductance and u.v-vis, spectroscopy. The complexes are ionic in nature and exhibit pentaeoordinated geometry around the metal ion. The reaction kinetics of C 25 H 36 N 5 O 2 CuCl with calf thymus DNA was studied by u.v-vis, spectroscopy in aqueous medium. The complex after interaction with calf thymus DNA shows shift in the absorption spectrum and hypochromicity indicating an intercalative binding mode. The K obs values have been calculated under pseudo-first order conditions. The redox behaviour of complex C 25 H 36 N 5 O 2 CuCl in the presence and in the absence of calf thymus DNA in the aqueous solution has been investigated by cyclic voltammetry. The cyclic voitammogram exhibits one quasi-reversible redox wave corresponding to Cu II / Cu I redox couple with E 1 / 2 values of -0.377 and -0.237 V respectively at a scan rate of 0.1V s - 1 .On interaction with calf thymus DNA, the complex C 25 H 36 N 5 O 2 CuCl exhibits shifts in both E p as well as in E 1 / 2 values, indicating strong binding of the complex to the calf thymus DNA. PMID:18475428

Polarization Mechanisms in Phase II Poly(Vinylidene Fluoride) Films.

DTIC Science & Technology

1981-11-12

34 OdRO a mnk W) Poly(Vinylidene Fluoride), x-rays, piezelectricity, polarization, poling FAWWRmCT ffls~ -ew nam 9 Uf"Oo me..Mv £*mM NOWsA Unoriented...phase II films were poled with fields up to 3.2 MV/cm at room o) temperature. A determination of the piezoelectric strain coefficient provided a measure...sT. VW OtU.4LF-41U.4" ". . -. I u CIImVP CLAI IaICATIOM OV- VPI PU.I (Ul... O111 111..41 the poling field and different polarization mechanisms appear

U.S. Air Force Aircraft in Southeast Asia Tested by the Air Force Flight Test Center

DTIC Science & Technology

1970-03-01

rivalries of religious sects and powerful political factions. The United States, France, Great Britian, Thailand, Pakistan, New Zealand , Australia, and...Background A-lb Sky raider 0-1 Bird Dog 0-2 WU-2 U-3 F-U Phantom II and RF-fc F-5 Freedom Fignter A-7 Corsair II C-7 Caribou OV-10 Bronco...Aug 69 A new world speed record for piston engine airplanes was established by civilian pilot Darryl Greenamyer over a three-kilometer course laid

Relaxation kinetics of the interaction between RNA and metal-intercalators: the Poly(A).Poly(U)/platinum-proflavine system.

PubMed

Biver, Tarita; Secco, Fernando; Venturini, Marcella

2005-05-15

The interactions of Poly(A).Poly(U) with the cis-platinum derivative of proflavine [{PtCl(tmen)}(2){HNC(13)H(7)(NHCH(2)CH(2))(2)}](+) (PRPt) and proflavine (PR) are investigated by spectrophotometry, spectrofluorimetry and T-jump relaxation at I=0.2M, pH 7.0, and T=25 degrees C. Base-dye interactions prevail at high RNA/dye ratio and binding isotherms analysis reveals that both dyes bind to Poly(A).Poly(U) according to the excluded site model (n=2). Only one relaxation effect is observed for the Poly(A).Poly(U)/PRPt system, whereas two effects are observed with Poly(A).Poly(U)/PR. The results agree with the sequence D+S <==> D, S <==> DS(I) <==> DS(II), where D,S is an external complex, DS(I) is a partially intercalated species, and DS(II) is the fully intercalated complex. Formation of DS(II) could be observed in the case of proflavine only. This result is interpreted by assuming that the platinum-containing residue of PRPt hinders the full intercalation of the acridine residue.

United States Air Force Statistical Digest, Fiscal Year 1952. Seventh Edition

DTIC Science & Technology

1953-01-01

Off’icers E! Enlisted are reported on a "pay scale basis because ot’ the inclusion ot’ SCARiiAF Source: Personnel Statistical Division, DeS /Comptroller...D:: , ~. ;!~ ,~:! ilj rl"’ < ., 𔃺’ lai’. = 1~~ L,- l{H’=-... - I u, u, , !! ~iLL u, :; ~E! !LL <t ’" Ii Ii t-U I-et en u, a:l I I’I- 0 .. a...person in a theater of operatlOll8 Who beceaee a casualty as defiDed bererc , as a result of en outside force or agent or the eDelllY, il:J. the race of

Considerations for Integrating Women into Closed Occupations in the U.S. Special Operations Forces: Appendices

DTIC Science & Technology

2015-05-01

106 ii . Attachment/Support/Other Specialized Roles for Women ............................................. 107 iii. Separate Men and... ii . Attachment/Support/Other Specialized Roles for Women Responses included in this category include those that described different deployment

U.S. EPA, Pesticides, Label, MAQUAT 20-M, 12/9/2010

EPA Pesticide Factsheets

2011-04-13

... entire lawn to prevent spread of infection at least ... Escherichia coli (E. coli) and Staphylococcus aureus (Staph) are ... Y"ii:t~~ii:M 1~~~k;:~~1~~;;{i'~iTiQl ...

Prime Contractors with Awards Over $25,000 by Name, Location, and Contract Number. Fiscal Year 1993. (1079 Construction Corp-Centre Manufacturing Co Inc.). Part 1

DTIC Science & Technology

1994-03-01

EZ 8 44 1- 1.. z 4L ZP u u 0 w Pa8 d 4i) 0 4.z’ 04 ~u 0 4 ) 4.~0 0:. 0W .w- w A.0 tD U.4 0) 0 4 4 4 0W IEu 40 IA. 0 W 42 4n z 4E ww W ta U4 m 4 4 U L...N 0 0kI ~II~(~ ( ~0~c ~IC I N I~(~I~0 01C 4 N( 04i..4 II .4 󈧄W00 IC0 Q 44 -4 0ൈ 00 00 0 1 .Z0 0 00ZZ 4 Is,00 00 0 0 ZI0I wc > 0 3a I Q I4b oo...1 m 3t 024.223 E g r 𔃺 4 to wi L8 z- z . 4L c o Wm 4l H z " E. w 0~ 4lL 44 W a U3 TD W xP 4 j 4 ) W V) F-4 4 4 1 w2 C. : 40 ’s U Q IN 0 1 0 0 0 0

The Army Communicator and Mass Communication Law: An Analysis of Organizational and Personal Liability

DTIC Science & Technology

1988-01-01

iv Chapter I. INTRODUCTION.....................1 II. MILITARY PERSONNEL AND FREEDOM OF SPEECH . . . 7 III. ACCESS TO MILITARY INFORMATION...U.S. Army, Washington, DC, 26 January 1988. 6 CHAPTER II MILITARY PERSONNEL AND FREEDOM OF SPEECH The First Amendment to the U.S. Constitution states...34Congress shall make no law . . . abridging the freedom of speech , or of the press .... ,6 On initial examination, it would seem the Founding Fathers

Crimp-Imbalanced Protective (CRIMP) Fabrics

DTIC Science & Technology

2010-03-31

ILLUSTRATIONS ii LIST OF TABLES iv LIST OF ABBREVIATIONS, ACRONYMS, AND SYMBOLS iv INTRODUCTION 1 THREAT TYPES AND PROTECTION LEVELS 2 HISTORICAL...velocity 3-D Three-dimensional v (vi blank) CRIMP-IMBALANCED PROTECTIVE (CRIMP) FABRICS INTRODUCTION Lightweight, soft-armor systems have...1200 ft/sec D-4 (qi-uO /(B jaug UIBJJS 3i;sei3 (qi-uO 3* dSd ui uoipnpay > .’/ .7 • ’/ i •’/ !/ / *- IT> *- m y / II

Final Report: Molecular mechanisms and kinetics of microbial anaerobic nitrate-dependent U(IV) and Fe(II) oxidation

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Day, Peggy A.; Asta, Maria P.; Kanematsu, Masakazu

2015-02-27

In this project, we combined molecular genetic, spectroscopic, and microscopic techniques with kinetic and reactive transport studies to describe and quantify biotic and abiotic mechanisms underlying anaerobic, nitrate-dependent U(IV) and Fe(II) oxidation, which influences the long-term efficacy of in situ reductive immobilization of uranium at DOE sites. In these studies, Thiobacillus denitrificans, an autotrophic bacterium that catalyzes anaerobic U(IV) and Fe(II) oxidation, was used to examine coupled oxidation-reduction processes under either biotic (enzymatic) or abiotic conditions in batch and column experiments with biogenically produced UIVO2(s). Synthesis and quantitative analysis of coupled chemical and transport processes were done with the reactivemore » transport modeling code Crunchflow. Research focused on identifying the primary redox proteins that catalyze metal oxidation, environmental factors that influence protein expression, and molecular-scale geochemical factors that control the rates of biotic and abiotic oxidation.« less

An updated Type II supernova Hubble diagram

NASA Astrophysics Data System (ADS)

Gall, E. E. E.; Kotak, R.; Leibundgut, B.; Taubenberger, S.; Hillebrandt, W.; Kromer, M.; Burgett, W. S.; Chambers, K.; Flewelling, H.; Huber, M. E.; Kaiser, N.; Kudritzki, R. P.; Magnier, E. A.; Metcalfe, N.; Smith, K.; Tonry, J. L.; Wainscoat, R. J.; Waters, C.

2018-03-01

We present photometry and spectroscopy of nine Type II-P/L supernovae (SNe) with redshifts in the 0.045 ≲ z ≲ 0.335 range, with a view to re-examining their utility as distance indicators. Specifically, we apply the expanding photosphere method (EPM) and the standardized candle method (SCM) to each target, and find that both methods yield distances that are in reasonable agreement with each other. The current record-holder for the highest-redshift spectroscopically confirmed supernova (SN) II-P is PS1-13bni (z = 0.335-0.012+0.009), and illustrates the promise of Type II SNe as cosmological tools. We updated existing EPM and SCM Hubble diagrams by adding our sample to those previously published. Within the context of Type II SN distance measuring techniques, we investigated two related questions. First, we explored the possibility of utilising spectral lines other than the traditionally used Fe IIλ5169 to infer the photospheric velocity of SN ejecta. Using local well-observed objects, we derive an epoch-dependent relation between the strong Balmer line and Fe IIλ5169 velocities that is applicable 30 to 40 days post-explosion. Motivated in part by the continuum of key observables such as rise time and decline rates exhibited from II-P to II-L SNe, we assessed the possibility of using Hubble-flow Type II-L SNe as distance indicators. These yield similar distances as the Type II-P SNe. Although these initial results are encouraging, a significantly larger sample of SNe II-L would be required to draw definitive conclusions. Tables A.1, A.3, A.5, A.7, A.9, A.11, A.13, A.15 and A.17 are also available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/611/A25

Hazards/Failure Modes and Effects Analysis MK 1 MOD 0 LSO-HUD Console System.

DTIC Science & Technology

1980-03-24

AsI~f~ ! 127 = 3gc Z Isre -0 -q ~sI I I 𔃻~~~ ~ _ _ 3_______ II! -0udC Z Z’ P4 12 d-U * ~s ’:i~i42 S- 60 -, Uh ~ U3l I OM -C ~ . - U 4~ dcd 8U-q Ali...8 VI SCOPE AND METHODOLOGY OF ANALYSIS ........ 1O FIGURE 1: H/ FMEA /(SSA) WORK SHEET FORMAT ........... 14 APPENDIX A: HAZARD/FAILURE MODES AND...EFFECTS ANALYSIS (H/ FMEA ) -- WORK SHEETS ......... 15(A-O) TABLE: SUBSYSTEM: UNIT I Heads-Up Display Console .............. 17(A-1) UNIT 2 Auxiliary

U.S. EPA, Pesticide Product Label, TRIPLE ACTION 10-6-4 LITE WGT PLNT FD CRABGRSS PREVNTR INSECT CTRL, 04/02/1968

EPA Pesticide Factsheets

2011-04-19

li!"~:'i • 1l1t.

Mitogen-activated protein kinase is required for the behavioral desensitization that occurs after repeated injections of angiotensin II

PubMed Central

Vento, Peter J.; Daniels, Derek

2013-01-01

Angiotensin II (AngII) acts on central angiotensin type 1 (AT1) receptors to increase water and saline intake. Prolonged exposure to AngII in cell culture models results in a desensitization of the AT1 receptor that is thought to involve receptor internalization, and a behavioral correlate of this desensitization has been shown in rats after repeated central injections of AngII. Specifically, rats given repeated injections of AngII drink less water than controls after a subsequent test injection of AngII. Under the same conditions, however, repeated injections of AngII have no effect on AngII-induced saline intake. Given earlier studies indicating that separate intracellular signaling pathways mediate AngII-induced water and saline intake, we hypothesized that the desensitization observed in rats may be incomplete, leaving the receptor able to activate mitogen-activated protein (MAP) kinases (ERK1/2), which play a role in AngII-induced saline intake without affecting water intake. In support of this hypothesis, we found no difference in MAP kinase phosphorylation after an AngII test injection in rats given prior treatment with repeated injections of vehicle, AngII, or Sar1,Ile4,Ile8-AngII (SII), an AngII analog that activates MAP kinase without G protein coupling. In addition, we found that pretreatment with the MAP kinase inhibitor U0126 completely blocked the desensitizing effect of repeated AngII injections on water intake. Furthermore, AngII-induced water intake was reduced similarly by repeated injections of AngII or SII. The results suggest that G protein-independent signaling is sufficient to produce behavioral desensitization of the angiotensin system and that the desensitization requires MAP kinase activation. PMID:22581747

Mitogen-activated protein kinase is required for the behavioural desensitization that occurs after repeated injections of angiotensin II.

PubMed

Vento, Peter J; Daniels, Derek

2012-12-01

Angiotensin II (Ang II) acts on central angiotensin type 1 (AT(1)) receptors to increase water and saline intake. Prolonged exposure to Ang II in cell culture models results in a desensitization of the AT(1) receptor that is thought to involve receptor internalization, and a behavioural correlate of this desensitization has been shown in rats after repeated central injections of Ang II. Specifically, rats given repeated injections of Ang II drink less water than control animals after a subsequent test injection of Ang II. In the same conditions, however, repeated injections of Ang II have no effect on Ang II-induced saline intake. Given earlier studies indicating that separate intracellular signalling pathways mediate Ang II-induced water and saline intake, we hypothesized that the desensitization observed in rats may be incomplete, leaving the receptor able to activate mitogen-activated protein (MAP) kinases (ERK1/2), which play a role in Ang II-induced saline intake without affecting water intake. In support of this hypothesis, we found no difference in MAP kinase phosphorylation after an Ang II test injection in rats given prior treatment with repeated injections of vehicle, Ang II or Sar(1),Ile(4),Ile(8)-Ang II (SII), an Ang II analogue that activates MAP kinase without G protein coupling. In addition, we found that pretreatment with the MAP kinase inhibitor U0126 completely blocked the desensitizing effect of repeated Ang II injections on water intake. Furthermore, Ang II-induced water intake was reduced to a similar extent by repeated injections of Ang II or SII. The results suggest that G protein-independent signalling is sufficient to produce behavioural desensitization of the angiotensin system and that the desensitization requires MAP kinase activation.

75 FR 55257 - Definition of Federal Election Activity

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-10

... types of activity that are subject to these funding restrictions, including ``voter registration activity''--Type I Federal election activity--and GOTV activity--Type II Federal election activity. See 2 U... activity, Type II Federal election activity also includes ``voter identification'' and ``generic campaign...

U.S. EPA, Pesticide Product Label, RED PANTHER SUPER JUCE, 06/02/1971

EPA Pesticide Factsheets

2011-04-21

... " 1 ' .... 1. \\ ... 1 , ,.: r', .: • i":;c '\\ I, )1: !~'1' .\\~~I\\1.\\:.: 1" :'!( II·T "i: \\\\. 'II'll P'HI' "\\ l"Il:, I'! 'HI" 1:-:1'.', 'II~ \\\\.I! I-:HI: , J [ •• '. PANTHER JUCE . , ...

Performance evaluation type II and type IIA box beam end terminals--volume II : appendices.

DOT National Transportation Integrated Search

2010-01-10

Two types of guide rail end terminals were constructed and evaluated according to the American Association of State Highway : and Transportation Officials (AASHTOs) Manual for Assessing Safety Hardware (MASH). The guide rail end terminals are u...

U.S. EPA, Pesticide Product Label, CHACON ORNAMENTAL SPRAY, 03/24/1981

EPA Pesticide Factsheets

2011-04-14

,-. ., I I ~ '- . ; i I l 0 " j ,. '" 1 ~}.:. I \\ I " Ii jO ; i)c , <,! , i .:::: I '-OJ ! ., ,~ 0 -...!D-"- - • II r " ,? .' I I , I .(. i- I 0 , <1, {2 0 \\ " I ~ ! p t " ~ I " a " I) " \\ " " ...

A multi-center, randomized, clinical trial comparing adhesive polyurethane foam dressing and adhesive hydrocolloid dressing in patients with grade II pressure ulcers in primary care and nursing homes.

PubMed

Guillén-Solà, Mireia; Soler Mieras, Aina; Tomàs-Vidal, Antònia M

2013-12-21

Pressure ulcers (PrUs) are ischemic wounds in the skin and underlying tissues caused by long-standing pressure force over an external bone or cartilaginous surface. PrUs are an important challenge for the overall health system because can prolong patient hospitalization and reduce quality of life. Moreover, 95% of PrUs are avoidable, suggesting they are caused by poor quality care assistance. PrUs are also costly, increasing national costs. For example, they represent about 5% of overall annual health expenses in Spain. Stages I and II PrUs have a combined prevalence of 65%. According main clinical guidelines, stage II PrUs (PrU-IIs) are usually treated by applying special dressings (polyurethane or hydrocolloid). However, little scientific evidence regarding their efficacy has been identified in scientific literature. Our aim is to assess the comparative efficacy of adhesive polyurethane foam and hydrocolloid dressings in the treatment of PrU-IIs in terms of healed ulcer after 8 weeks of follow-up. This paper describes the development and evaluation protocol of a randomized clinical trial of two parallel treatment arms. A total of 820 patients with at least 1 PrU-II will be recruited from primary health care and home care centers. All patients will receive standardized healing procedures and preventive measures (e.g. positional changes and pressure-relieving support surfaces), following standardized procedures. The main outcome will be the percentage of wounds healed after 8 weeks. Secondary outcomes will include cost-effectiveness, as evaluated by cost per healed ulcer and cost per treated patient and safety evaluated by adverse events. This trial will address the hypothesis that hydrocolloid dressings will heal at least 10% more stage II PrUs and be more cost-effective than polyurethane foam dressings after 8 weeks. This trial has been registered with controlled-trials number ISCRCTN57842461 and EudraCT 2012-003945-14.

The Motivational Effects of Gender, Residency, Worldview, and Acculturation Towards Science Study at American Institutes of Higher Education

NASA Astrophysics Data System (ADS)

Doppke, Max George

This non-experimental, quantitative exploratory study examined the relationship between genders, student residency status, acculturation, worldviews, and the motivation towards science education for a group of 291 undergraduate students in the United States. As all demographic variables were nominal, and all survey variables were ordinal, associations and differences utilized non-parametric statistical procedures. The overall design was descriptive, comparative, and correlational. Spearman's rho signified that there was a moderate positive correlation between the total scores on the Worldview Analysis Scale (WAS) and the total scores on the Science Motivation Questionnaire-II (SMQ-II; rs = .393, *p< .01, two-tailed). A Goodman and Kruskal's Gamma was conducted to determine the association between the seven subscales of the Worldview Assessment Survey (WAS) and the five subscales of the Science Motivation Questionnaire -II (SMQ-II). The results showed a moderate to strongly moderate, positive association between WAS Communalism (WASCOM) and the SMQ-II subscales of intrinsic motivation (SMQINTR; G = .322, p<.0005); self-efficacy (SMQSELF; G = .350, p< .0005); career motivation (SMQCAR; G = .307, p< .0005); and self-determination (SMQSELFDET; G = .364, p< .0005). A Mann-Whitney U test was run on the Worldview Analysis Scale (WAS) and the Science Motivation Questionnaire-II (SMQ-II) to determine if differences in score were based on gender. The WAS score was statistically significantly higher in males (Median = 180.00) than in females ( Median = 164.00, U = 8521.500, z = -2.840, p = .005). . The SMQ-II score was statistically insignificantly higher in males (Median = 152.56) than in females (Median = 140.08, U = 9652.500, z = -1.263, p = .207). In following the fundamental dictates of social research, this study offered a thorough description of a situation that ultimately provokes various possible explanations as necessary conclusions to intellectually stimulating thought, without the burden of propagating dubious inferences through unwarranted deterministic or probabilistic causality. Recommendations for future work include mixed-method studies with interviews, longitudinal studies, instructor-student studies, and gender vs. sexual orientation studies.

Magnetic susceptibility of alkali-tetracyanoquinodimethane salts and extended Hubbard models with bond order and charge density wave phases

NASA Astrophysics Data System (ADS)

Kumar, Manoranjan; Topham, Benjamin J.; Yu, RuiHui; Ha, Quoc Binh Dang; Soos, Zoltán G.

2011-06-01

The molar spin susceptibilities χ(T) of Na-tetracyanoquinodimethane (TCNQ), K-TCNQ, and Rb-TCNQ(II) are fit quantitatively to 450 K in terms of half-filled bands of three one-dimensional Hubbard models with extended interactions using exact results for finite systems. All three models have bond order wave (BOW) and charge density wave (CDW) phases with boundary V = Vc(U) for nearest-neighbor interaction V and on-site repulsion U. At high T, all three salts have regular stacks of TCNQ^- anion radicals. The χ(T) fits place Na and K in the CDW phase and Rb(II) in the BOW phase with V ≈ Vc. The Na and K salts have dimerized stacks at T < Td while Rb(II) has regular stacks at 100 K. The χ(T) analysis extends to dimerized stacks and to dimerization fluctuations in Rb(II). The three models yield consistent values of U, V, and transfer integrals t for closely related TCNQ^- stacks. Model parameters based on χ(T) are smaller than those from optical data that in turn are considerably reduced by electronic polarization from quantum chemical calculation of U, V, and t of adjacent TCNQ^- ions. The χ(T) analysis shows that fully relaxed states have reduced model parameters compared to optical or vibration spectra of dimerized or regular TCNQ^- stacks.

75 FR 16204 - Region II Buffalo District Advisory Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... SMALL BUSINESS ADMINISTRATION Region II Buffalo District Advisory Council; Public Meeting AGENCY: U.S. Small Business Administration. ACTION: Notice of open Federal advisory committee meeting... roundtable discussion on small business issues. FOR FURTHER INFORMATION CONTACT: The meeting is open to the...

77 FR 20871 - Region II Buffalo District Advisory Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... SMALL BUSINESS ADMINISTRATION Region II Buffalo District Advisory Council; Public Meeting AGENCY: U.S. Small Business Administration. ACTION: Notice of open federal advisory committee meeting... business issues. FOR FURTHER INFORMATION CONTACT: The meeting is open to the public however advance notice...

76 FR 59480 - Region II Buffalo District Advisory Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-26

... SMALL BUSINESS ADMINISTRATION Region II Buffalo District Advisory Council; Public Meeting AGENCY: U.S. Small Business Administration. ACTION: Notice of open Federal advisory committee meeting... discussion on small business issues. FOR FURTHER INFORMATION CONTACT: The meeting is open to the public...

U10 : Trusted Truck(R) II (phase B).

DOT National Transportation Integrated Search

2009-01-01

Phase B of the Trusted Truck II project built on the system developed in Phase A (or Year 1). For the implementation portion of the project, systems were added to the trailer to provide additional diagnostic trailer data that can be sent to the TTM...

U.S. EPA, Pesticide Product Label, , 06/08/1972

EPA Pesticide Factsheets

2011-04-21

... _"I" ""I,,,n r.'I"If'·~ .. to'IOll :,,' • I",n~ .. ' ~ o' " .. , f .. , ~"I c •• ·.r.It.· r r"II' 1!I .. lIt" "'; 'II rot- gUilt "Iil"'." . rut .. h",nm .. .tt- " _ iI"'''h I ... " . Ih.lt ... ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Discussion Session - Accelerator System Design (Part II) Tutors: C. Darve, J. Weisend II, Ph. Lebrun, A. Dabrowski, U. Raich Video Conference with the CERN Control Center. Experts in the field of Accelerator science will be available to answer the students questions. This session will link the CCC and SA (using Codec VC).

Properties of Aircraft Fuels and Related Materials

DTIC Science & Technology

1985-08-01

1.149 0.7681 25.1 59 0 F - - 0.7563 - 70OF 70 0.872 0.7513 23.2 100OF 125 0.719 0.7378 21.6 140OF 255 0.587 0.7206 19.6 15 tD TABLE 4 (continued) Vapor...0Cal * 00 00 0* 00 0* 0U 0 0- 0 0 0 03 0o -’ 0- I 00Caj = 0w 0 - 0 0ki 9’ 4.1 0 0 -u - * 0 -u h. 0,I!i I A n 4 Ew Ii 0 * 66.6 0w@ 0zw@ 0 0Ag 0ID

Synthesis, Characterization and the Corrosion Inhibition Study of Two Schiff Base Ligands Derived From Urea and Thiourea and Their Complexes with Cu(II) and Hg(II) Ions

NASA Astrophysics Data System (ADS)

Alwan, Wasan Mohammed

2018-05-01

The research includes synthesis of [L1] and [L2] Schiff base ligands by the reaction of vanillin with urea and thiourea respectively in 2:1 mol ratio. The two ligands were reacted with CuII ion in 1:2 mol ratio and HgII ion in 1:1 mol ratio. The prepared compounds have been identified by FTIR, U.V-Vis, 1H-NMR (L1, L2 and HgII complex) spectroscopies, microelemental analysis (C.H.N.S), magnetic susceptibility measurements, atomic absorption, chloride content along with conductivity and melting point measurements. According to applied characterization methods, the proposed general formulas of CuII and HgII complexes were [Cu2LnCl4] and [HgLnCl]Cl, respectively, (where n = 1, 2). The ability of corrosion inhibition with two ligands and their cupper complexes has been studied in diluted hydrochloric acid media.

Properties of Aircraft Fuels and Related Materials.

DTIC Science & Technology

1991-07-29

LA . 0I Z La u0I Z4 Li LA . L U) a:L) mi F- - L Wz N ) Mtwm Li La . N t o) a f) r en f" ’m, Mww 4v Nv NuQe...mo 000) 0 100 U4v4U1 w 70 w n(~xI I ! I- I I iI I i I I I I Ii I I I " LJLaJ La . LaJLI 0 0 L.. ao . 0 .L 0 EL 17z U. Z IV CD 0 Iqx 0 1 O0 cN.. 10. In...notice on a specific document. INCLASSIFIED ECURITY CLASSIFICATION OF THIS PAGE IForm Approved REPORT DOCUMENTATION PAGE MB No, 0704-0188 la .

The PIP-II Conceptual Design Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ball, M.; Burov, A.; Chase, B.

2017-03-01

The Proton Improvement Plan-II (PIP-II) encompasses a set of upgrades and improvements to the Fermilab accelerator complex aimed at supporting a world-leading neutrino program over the next several decades. PIP-II is an integral part of the strategic plan for U.S. High Energy Physics as described in the Particle Physics Project Prioritization Panel (P5) report of May 2014 and formalized through the Mission Need Statement approved in November 2015. As an immediate goal, PIP-II is focused on upgrades to the Fermilab accelerator complex capable of providing proton beam power in excess of 1 MW on target at the initiation of themore » Long Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) program, currently anticipated for the mid- 2020s. PIP-II is a part of a longer-term goal of establishing a high-intensity proton facility that is unique within the world, ultimately leading to multi-MW capabilities at Fermilab....« less

U6 small nuclear RNA is transcribed by RNA polymerase III.

PubMed Central

Kunkel, G R; Maser, R L; Calvet, J P; Pederson, T

1986-01-01

A DNA fragment homologous to U6 small nuclear RNA was isolated from a human genomic library and sequenced. The immediate 5'-flanking region of the U6 DNA clone had significant homology with a potential mouse U6 gene, including a "TATA box" at a position 26-29 nucleotides upstream from the transcription start site. Although this sequence element is characteristic of RNA polymerase II promoters, the U6 gene also contained a polymerase III "box A" intragenic control region and a typical run of five thymines at the 3' terminus (noncoding strand). The human U6 DNA clone was accurately transcribed in a HeLa cell S100 extract lacking polymerase II activity. U6 RNA transcription in the S100 extract was resistant to alpha-amanitin at 1 microgram/ml but was completely inhibited at 200 micrograms/ml. A comparison of fingerprints of the in vitro transcript and of U6 RNA synthesized in vivo revealed sequence congruence. U6 RNA synthesis in isolated HeLa cell nuclei also displayed low sensitivity to alpha-amanitin, in contrast to U1 and U2 RNA transcription, which was inhibited greater than 90% at 1 microgram/ml. In addition, U6 RNA synthesized in isolated nuclei was efficiently immunoprecipitated by an antibody against the La antigen, a protein known to bind most other RNA polymerase III transcripts. These results establish that, in contrast to the polymerase II-directed transcription of mammalian genes for U1-U5 small nuclear RNAs, human U6 RNA is transcribed by RNA polymerase III. Images PMID:3464970

Identification of members of the gonadotropin-releasing hormone (GnRH), corticotropin-releasing factor (CRF) families in the genome of the holocephalan, Callorhinchus milii (elephant shark).

PubMed

Nock, Tanya G; Chand, Dhan; Lovejoy, David A

2011-04-01

The gonadotropin-releasing hormone (GnRH) and corticotropin-releasing family (CRF) are two neuropeptides families that are strongly conserved throughout evolution. Recently, the genome of the holocephalan, Callorhinchus milii (elephant shark) has been sequenced. The phylogenetic position of C. milii, along with the relatively slow evolution of the cartilaginous fish suggests that neuropeptides in this species may resemble the earliest gnathostome forms. The genome of the elephant shark was screened, in silico, using the various conserved motifs of both the vertebrate CRF paralogs and the insect diuretic hormone sequences to identify the structure of the C. milii CRF/DH-like peptides. A similar approach was taken to identify the GnRH peptides using conserved motifs in both vertebrate and invertebrate forms. Two CRF peptides, a urotensin-1 peptide and a urocortin 3 peptide were found in the genome. There was only about 50% sequence identity between the two CRF peptides suggesting an early divergence. In addition, the urocortin 2 peptide seems to have been lost and was identified as a pseudogene in C. milii. In contrast to the number of CRF family peptides, only a GnRH-II preprohormone with the conserved mature decapeptide was found. This confirms early studies about the identity of GnRH in the Holocephali, and suggests that the Holocephali and Elasmobranchii differ with respect to GnRH structure and function. Copyright © 2011 Elsevier Inc. All rights reserved.

Hormonal regulation of lipid metabolism in developing coho salmon, Oncorhynchus kisutch

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sheridan, M.A.

1985-01-01

Lipid metabolism in juvenile coho salmon is characterized, and adaptive changes in lipid mobilization are described in relation to development and hormonal influences. The rates of lipogenesis and lipolysis were determined in selected tissues of juvenile salmon during the period of seawater preadaptive development (smoltification). Neutral lipid (sterol) and fatty acid synthesis in the liver and mesenteric fat was measured by tritium incorporation. Fatty acid synthesis in the liver and mesenteric fat decreased by 88% and 81%, respectively, between late February (parr) and early June (smolt). To assess the role of hormones in smoltification-associated lipid depletion, growth hormone, prolactin, thyroxinmore » and cortisol were administered in vivo early in development (parr) to determine if any of these factors could initiate the metabolic responses normally seen later in development (smolt). Growth hormone stimulated lipid mobilization from coho salmon parr. Prolactin strongly stimulated lipid mobilization in coho parr. Thyroxin and cortisol also stimulated lipid mobilization for coho salmon parr. The direct effect of hormones was studied by in vitro pH-stat incubation of liver slices. These data suggest that norepinephrine stimulates fatty acid release via ..beta..-adrenergic pathways. Somatostatin and its partial analogue from the fish caudal neurosecretory system, urotensin II, also affect lipid mobilization. These results establish the presence of hormone-sensitive lipase in salmon liver and suggest that the regulation of lipid metabolism in salmon involves both long-acting and short-acting hormonal agents.« less

Results of the post-U.S. Food and Drug Administration-approval study with a continuous flow left ventricular assist device as a bridge to heart transplantation: a prospective study using the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support).

PubMed

Starling, Randall C; Naka, Yoshifumi; Boyle, Andrew J; Gonzalez-Stawinski, Gonzalo; John, Ranjit; Jorde, Ulrich; Russell, Stuart D; Conte, John V; Aaronson, Keith D; McGee, Edwin C; Cotts, William G; DeNofrio, David; Pham, Duc Thinh; Farrar, David J; Pagani, Francis D

2011-05-10

The aim of this study was to determine whether results with the HeartMate (HM) II left ventricular assist device (LVAD) (Thoratec Corporation, Pleasanton, California) in a commercial setting are comparable to other available devices for the same indication. After a multicenter pivotal clinical trial conducted from 2005 to 2008, the U.S. Food and Drug Administration approved the HM II LVAD for bridge to transplantation (BTT). A post-approval study was required by the U.S. Food and Drug Administration to determine whether results with the device in a commercial setting are comparable to other available devices for the same indication. The study was a prospective evaluation of the first 169 consecutive HM II patients enrolled in the national INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) who were listed for transplant or likely to be listed. Patients were enrolled from April through August 2008 at 77 U.S. centers and followed for at least 1 year after implant. A comparison group (COMP) included all patients (n = 169 at 27 centers) enrolled in the INTERMACS registry with other types of LVADs (79% HeartMate XVE, 21% Implantable Ventricular Assist Device [Thoratec Corporation]) for the same BTT indication in the same time period. Survival rates, adverse events, and quality of life with the EuroQol EQ-5D visual analog scale were obtained in the INTERMACS registry. Baseline characteristics were similar, but creatinine and blood urea nitrogen were lower in the HM II versus COMP groups, and there were fewer patients in the highest-risk INTERMACS patient profile Number 1 (24% for HM II vs. 39% for COMP). Adverse event rates were similar or lower for HM II versus COMP for all events. Bleeding was the most frequent adverse event for both groups (1.44 vs. 1.79 events/patient-year). Operative 30-day mortality for HM II was 4% versus 11% for COMP. The percentage of patients reaching transplant, cardiac recovery, or ongoing LVAD support by 6 months was 91% for HM II and 80% for COMP, and the Kaplan-Meier survival for patients remaining on support at 1 year was 85% for HM II versus 70% for COMP. Quality of life was significantly improved at 3 months of support and sustained through 12 months in both groups compared with baseline. The results in a post-market approval, actual patient care setting BTT population support the original findings from the pivotal clinical trial regarding the efficacy and risk profile of the HM II LVAD. These data suggest that dissemination of this technology after approval has been associated with continued excellent results. Copyright © 2011 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

U.S. EPA, Pesticide Product Label, LIQUID CHLORINE, 12/20/1991

EPA Pesticide Factsheets

2011-04-19

... 11111- • '.Ut. QInt,,. Pn:I:8lr .. SII "'"1., •• "11" , .. " 1101. t. III "",.1. oil "' epr.r,,._,. All CU"·':l1 c,.tll •• ,., IlClt.ll, tllll' .. 11 .. , II (IIU" .,. • 1,. IU ~. II.tIlI,. ...

U.S. EPA, Pesticide Product Label, ISOTOX INSECT KILLER FORMULA IV, 11/19/1992

EPA Pesticide Factsheets

2011-04-13

... StIr.bs ,"'1 "" f ,lpl\\ ] T: s II ' : I ,';' T • j' , •• , S; 'do ... ~t" '''stCII 0' /fI,tn II, plfler~ oriel-jon" ~.-t;, \\ "~l "~' -td R'.-Ul,t 'f''''nlahon occur, For Mfilybul~"IOw.' ...

Occupational Information 1990/91. Volume II.

ERIC Educational Resources Information Center

Nebraska Univ., Lincoln. Nebraska Career Information System.

The Nebraska Occupational Information books (volumes I and II) contain information about 386 different occupations in the state and answer questions about specific occupations in detail. The descriptions are arranged according to a U.S. Department of Labor classification system, with occupational titles clustered in general groups of selected…

32 CFR 903.1 - Mission and responsibilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the education and training programs satisfy the school's mission. (ii) Informs HQ USAFA/RR of... or do not accept appointment to a U.S. Service Academy. (v) Issues ID cards. (5) Headquarters USAFA... possible. (ii) Issues “Invitation to Travel” letters to all accepted cadet candidates (including civilians...

32 CFR 903.1 - Mission and responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the education and training programs satisfy the school's mission. (ii) Informs HQ USAFA/RR of... or do not accept appointment to a U.S. Service Academy. (v) Issues ID cards. (5) Headquarters USAFA... possible. (ii) Issues “Invitation to Travel” letters to all accepted cadet candidates (including civilians...

32 CFR 903.1 - Mission and responsibilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the education and training programs satisfy the school's mission. (ii) Informs HQ USAFA/RR of... or do not accept appointment to a U.S. Service Academy. (v) Issues ID cards. (5) Headquarters USAFA... possible. (ii) Issues “Invitation to Travel” letters to all accepted cadet candidates (including civilians...

32 CFR 903.1 - Mission and responsibilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the education and training programs satisfy the school's mission. (ii) Informs HQ USAFA/RR of... or do not accept appointment to a U.S. Service Academy. (v) Issues ID cards. (5) Headquarters USAFA... possible. (ii) Issues “Invitation to Travel” letters to all accepted cadet candidates (including civilians...

78 FR 1574 - Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... Infusion Pumps. 281 Requirements for the 0910-AG59 Testing and Reporting of Tobacco Product Constituents... Use Devices: Issuance of Draft Special Controls Guidance for Infusion Pumps Legal Authority: 21 U.S.C... proposing to amend the classification of infusion pumps from class II (performance standards) to class II...

Geochemical control on uranium(IV) mobility in a mining-impacted wetland.

PubMed

Wang, Yuheng; Bagnoud, Alexandre; Suvorova, Elena; McGivney, Eric; Chesaux, Lydie; Phrommavanh, Vannapha; Descostes, Michael; Bernier-Latmani, Rizlan

2014-09-02

Wetlands often act as sinks for uranium and other trace elements. Our previous work at a mining-impacted wetland in France showed that a labile noncrystalline U(IV) species consisting of U(IV) bound to Al-P-Fe-Si aggregates was predominant in the soil at locations exhibiting a U-containing clay-rich layer within the top 30 cm. Additionally, in the porewater, the association of U(IV) with Fe(II) and organic matter colloids significantly increased U(IV) mobility in the wetland. In the present study, within the same wetland, we further demonstrate that the speciation of U at a location not impacted by the clay-rich layer is a different noncrystalline U(IV) species, consisting of U(IV) bound to organic matter in soil. We also show that the clay-poor location includes an abundant sulfate supply and active microbial sulfate reduction that induce substantial pyrite (FeS2) precipitation. As a result, Fe(II) concentrations in the porewater are much lower than those at clay-impacted zones. U porewater concentrations (0.02-0.26 μM) are also considerably lower than those at the clay-impacted locations (0.21-3.4 μM) resulting in minimal U mobility. In both cases, soil-associated U represents more than 99% of U in the wetland. We conclude that the low U mobility reported at clay-poor locations is due to the limited association of Fe(II) with organic matter colloids in porewater and/or higher stability of the noncrystalline U(IV) species in soil at those locations.

Removal and mineralization of polycyclic aromatic hydrocarbons by litter-decomposing basidiomycetous fungi.

PubMed

Steffen, K T; Hatakka, A; Hofrichter, M

2002-10-01

Nine strains of litter-decomposing fungi, representing eight species of agaric basidiomycetes, were tested for their ability to remove a mixture of three polycyclic aromatic hydrocarbons (PAHs) (total 60 mg l(-1)) comprising anthracene, pyrene and benzo(a)pyrene (BaP) in liquid culture. All strains were able to convert this mixture to some extent, but considerable differences in degradative activity were observed depending on the species, the Mn(II) concentration, and the particular PAH. Stropharia rugosoannulata was the most efficient degrader, removing or transforming BaP almost completely and about 95% of anthracene and 85% of pyrene, in cultures supplemented with 200 micro M Mn(II), within 6 weeks. In contrast less than 40, 18, and 50% BaP, anthracene and pyrene, respectively, were degraded in the absence of supplemental Mn(II). In the case of Stropharia coronilla, the presence of Mn(II) led to a 20-fold increase of anthracene conversion. The effect of manganese could be attributed to the stimulation of manganese peroxidase (MnP). The maximum activity of MnP increased in S. rugosoannulata cultures from 10 U l(-1) in the absence of Mn(II) to 320 U l(-1) in Mn(II)-supplemented cultures. The latter degraded about 6% of a (14)C-labeled BaP into (14)CO(2) whereas only 0.7% was mineralized in the absence of Mn(II). In solid-state straw cultures, S. rugosoannulata, S. coronilla and Agrocybe praecox mineralized between 4 and 6% of (14)C-labeled BaP within 12 weeks.

Effect of Cu(II) coordination compounds on the activity of antioxidant enzymes catalase and superoxide dismutase in patients with colorectal cancer.

PubMed

Kubiak, Katarzyna; Malinowska, Katarzyna; Langer, Ewa; Dziki, Łukasz; Dziki, Adam; Majsterek, Ireneusz

2011-03-01

Colorectal cancer (CRC) is a serious medical and economical problem of our times. It is the most common gastrointestinal cancer in the world. In Poland, the treatment and detection of CRC are poorly developed and the pathogenesis is still unclear. One hypothesis suggests a role of reactive oxygen species (ROS) in the pathogenesis of CRC. Experimental studies in recent years confirm the participation of ROS in the initiation and promotion of CRC. The aim of the study was to examine the effect of the following coordination compounds coordination compounds: dinitrate (V) tetra(3,4,5-trimethyl-N1-pyrazole-κN2) copper(II), dichloro di(3,4,5-trimethyl-N1-pyrazole-κN2) copper(II), dinitrate (V) di(1,4,5-trimethyl-N1-pyrazole-κN2) copper(II), dichloro di(1,3,4,5-tetramethyl-N1-pyrazole-κN2) copper(II) on the activity of antioxidant enzymes superoxide dismutase (SOD, ZnCu-SOD) and catalase (CAT) in a group of patients with colorectal cancer (CRC) and in the control group consisting of patients with minor gastrointestinal complaints. The study was conducted in 20 patients diagnosed with colorectal cancer at the age of 66.5±10.2 years (10 men and 10 women) versus the control group of 20 people (10 men and 10 women) aged 57.89±17.10 years without cancer lesions in the biological material - hemolysate prepared in a proportion of 1ml of water per 1 ml of blood. CAT activity was measured by the Beers method (1952), while SOD activity was measured by the Misra and Fridovich method (1972). We found that patients with CRC showed a statistically significant decrease of SOD and CAT activity (CAT - 12,75±1.97 U/g Hb, SOD - 1111.52±155.52 U/g Hb) in comparison with the control group (CAT - 19.65±2,17 U/g Hb, SOD - 2046.26±507.22 U/g Hb). Simultaneously, we observed that the investigated coordination compounds of Cu(II) significantly increased the antioxidant activity of CAT and SOD in patients with CRC (mean: CAT 25.23±4.86 U/g Hb, SOD - 3075.96±940.20 U/g Hb). Patients with colorectal cancer are characterized by reduced activity of antioxidant enzymes catalase and superoxide dismutase which suggests impaired antioxidant barrier. Therefore, coordination compounds of Cu (II), which enhance the activity of CAT and SOD, may prove useful in the prevention and treatment of colorectal cancer.

17 CFR 240.13d-102 - Schedule 13G-Information to be included in statements filed pursuant to § 240.13d-1(b), (c), and...

Code of Federal Regulations, 2011 CFR

2011-04-01

...) [ ] Group, in accordance with § 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance... § 240.13d-1(b)(1)(ii)(K) and a member of the group is a non-U.S. institution eligible to file pursuant... group (a) (see instructions) (b) (3) SEC use only (4) Citizenship or place of organization Number of...

17 CFR 240.13d-102 - Schedule 13G-Information to be included in statements filed pursuant to § 240.13d-1(b), (c), and...

Code of Federal Regulations, 2012 CFR

2012-04-01

...) [ ] Group, in accordance with § 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance... a member of the group is a non-U.S. institution eligible to file pursuant to § 240.13d-1(b)(1)(ii)(J... No.___ (1) Names of reporting persons (2) Check the appropriate box if a member of a group (a) (see...

17 CFR 240.13d-102 - Schedule 13G-Information to be included in statements filed pursuant to § 240.13d-1(b), (c), and...

Code of Federal Regulations, 2010 CFR

2010-04-01

...) [ ] Group, in accordance with § 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance... § 240.13d-1(b)(1)(ii)(K) and a member of the group is a non-U.S. institution eligible to file pursuant... No.___ (1) Names of reporting persons (2) Check the appropriate box if a member of a group (a) (see...

On the Impact of Injection Schemes on Transition in Hypersonic Boundary Layers

DTIC Science & Technology

2009-10-13

e (1 − r ) – CpTw] [1] where r is the recovery factor. For...9.72 MJ/kg Reynolds number (Re x ) [-] S ta n to n n u m b e r (S t) [ -] experimental laminar Van Driest II White & Christoph Figure 4...h0 = 10.22 MJ/kg Reynolds number (Re x ) [-] S ta n to n n u m b e r (S t) [ -] experimental laminar Van Driest II White & Christoph 10 6 10

17 CFR 240.13d-102 - Schedule 13G-Information to be included in statements filed pursuant to § 240.13d-1(b), (c), and...

Code of Federal Regulations, 2013 CFR

2013-04-01

...) [ ] Group, in accordance with § 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance... a member of the group is a non-U.S. institution eligible to file pursuant to § 240.13d-1(b)(1)(ii)(J... No.___ (1) Names of reporting persons (2) Check the appropriate box if a member of a group (a) (see...

17 CFR 240.13d-102 - Schedule 13G-Information to be included in statements filed pursuant to § 240.13d-1(b), (c), and...

Code of Federal Regulations, 2014 CFR

2014-04-01

...) [ ] Group, in accordance with § 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance... a member of the group is a non-U.S. institution eligible to file pursuant to § 240.13d-1(b)(1)(ii)(J... No.___ (1) Names of reporting persons (2) Check the appropriate box if a member of a group (a) (see...

Agreement Between the United States Secret Service and the Department of Defense Concerning Protection of the President and Other Officials

DTIC Science & Technology

1986-09-17

States Secret Service, in accordance with the responsibilities of the Secret Service as authorized by Section 3056, Title 18, U.S. Code; and Section 202 of...Title 3, U.S. Code. II. General Responsibilities Subject to the direction of the Secretary of the Treasury, the Secret Service is authorized to... the Secret Service, other than those persons or positions specifically identified under "II General Responsibilities" in this agreement, will be

Corps Level Operational Art in Vietnam: A Study of II Field Force Commanders during Major Named Operations

DTIC Science & Technology

2013-05-23

South Vietnam and the bombing campaign falling short of its desired effects, options generated by the administration’s Whiz Kids or civilian...The Washington Post, 7 July 2009, http://articles.washingtonpost.com (accessed 5 October 2012), The term Whiz Kid refers to young 6...the U.S. Department of Defense by implementing a statistics based management approach. Whiz kid originated from a group or former World War II U.S. Air

Air Weather Service (AWS) Climatic Briefs: Europe.

DTIC Science & Technology

1982-05-01

UNCLASSIFIED USAFETAC/DS-/81/05b SBI-AD-ESS0 187 N1 II NI I MEhhhh IIIIIIIIIIIIIIIII II hh PHOTOGRAPH THIS SHEET E /8 LEVEL INVENTORY DOCUMENT IDENTIFICATION...JUSTIFICATnON S ELE3 C T E BY S U 3M DISTRIBUTIO - D AVAILABILITY CODES DIST AVAIL AND/OR SPECIAL DATE ACCESSIONED DISTRIBUTION STAMP 82 08 02 147...publication. WAYNE E McCOLLOM Chief, chnical Information Section FOR THE COMMANDER WALTER S. BURGMANN Scientific and Technical Information Officer (STINFO) ii

Department of State Strategic Planning Workshop II. Center for Strategic Leadership Issue Paper, Volume 01-02

DTIC Science & Technology

2002-04-01

Strategic Leadership 650 Wright Avenue Carlisle, PA 170l3-5049 OFFICIAL BUSINESS DEPARTMENT OF STATE STRATEGIC PLANNING WORKSHOP II U.S. ARMY WAR COLLEGE CSL 4 ...April 2002 Issues Paper 01-02 Department of State Strategic Planning Workshop II By Colonel Jeffrey C. Reynolds A State Department request, made...at the senior level, asked the Army Chief of Staff if the Army could help State improve its capacity to undertake strategic planning. In April

Micro-PROUST.

DTIC Science & Technology

1985-06-01

Noah needs to keep track of rainfall in the New Haven area in order to determine when to launch his ark . Write a...UNLSIIDFG92 N 2.. II4II 111220 11111 11J.4 MICROCOPY RESOLUTION TEST CHART S "- )ARDS 1963 A S !!? Ii~ Sii ". . . ," .’ "" o o." .* -. ° . ". * -. * " . -- I...unflagging effort and support in seeing this project through to fruition. V 7 .. ° - . . - , .-. - . - ., S .-’ S 1. ES , " , - u < . i ’ - SiCU,r7

Incoherent and Laser Photodeposition on Thin Films.

DTIC Science & Technology

1980-09-01

wavelength, an incoherent Oriel Mercury arc lamp (model HR-l) with a 1000 watt u-v out- a put centered at 2537A was used. This source emitted o down...Royal Society of London Series A, 156: 108-129 (1936). 18. Gutowsky, H.S.. "The Infra-Red and Raman Spectra of Dimethyl Mercury and Dimethyl Zinc," The...II), - Cadmium (II) and - Mercury (II)," Spectrochimica Acta, 33A: 669-680 (1977). 20. Bakke, A.M.W.. "A Molecular Structure Study of Dimethylmercury

Report on the Installation and Testing of the Advanced Weather Interactive Processing System (AWIPS II) for U.S. Navy Applications

DTIC Science & Technology

2018-04-24

Environment (CAVE). The report also details NRL’s work in extending AWIPS II EDEX to ingest and decode a Navy movement report instructions (MOVREP...phase of this work involved obtaining a copy of the AWIPS II client, the Common Access Visualization Environment (CAVE) as well as a copy of the server...assess the development environment of CAVE for supporting a Navy specific application. In consultation with FWC-San Diego we chose to work with

Navy Ship Names: Background for Congress

DTIC Science & Technology

2010-07-21

express the sense of the House that the Secretary of the Navy should name the next appropriate naval ship in honor of World War II Medal of Honor...named for Fleet Admiral Chester Nimitz, a five-star admiral who commanded U.S. and allied forces in the Pacific in World War II . Nimitz died in 1966, the...same year that Congress considered the FY1967 defense budget that funded the procurement of CVN-68. 9 Warner served as a sailor in World War II , as

Navy Ship Names: Background for Congress

DTIC Science & Technology

2009-10-20

big deck amphibious assault ships were named for World War II -era Navy aircraft carriers and earlier Navy ships. • Lewis and Clark (TAKE-1) class...8 Warner served as a sailor in World War II , as a Marine in the Korean War, as Under Secretary of the Navy in 1969- 1972...States has not built since World War II ) be named after states. 12 The Naval Institute Guide to the Ships and Aircraft of the U.S. Fleet, op cit, p

Navy Ship Names: Background for Congress

DTIC Science & Technology

2010-07-02

would express the sense of the House that the Secretary of the Navy should name the next appropriate naval ship in honor of World War II Medal of...68 was named for Fleet Admiral Chester Nimitz, a five-star admiral who commanded U.S. and allied forces in the Pacific in World War II . Nimitz died in...War II , as a Marine in the Korean War, as Under Secretary of the Navy in 1969- 1972, and as Secretary of the Navy in 1972-1974. Warner served as a

The Frequency Response and Operating Characteristics of the XR-3 Loads and Motions Program

DTIC Science & Technology

1976-06-01

TD -t- M - \\ \\ t:5Tt \\ ’X ^pl 1 \\ \\\\ 1 1 1 r ^ ’ 1 ^ ;f<i^^ ’ 1:^’ ’ 1 ’ 1 \\ J ) i ! r ;i 1 MM III I’MrMr^m 1 1 ’ 1 111’ 1 : ; 11 I ! i ; ! i...Operating Characteristics V=30 kts, A=0.3 ft, Ahead Seas 92 + 1 i h +- .... ^ _|_ „ . . , 1 , . . . , .,_ . , 1 J _lJ 1 i I .. ._ ., . td ii ! ! 1 1 1 T 1...rrPP I 1 1 i-j-K -w III -r-f-j-^- 1 1 i 1 --i*i- -r-HJ-U+f u**—^—^ .^ -« td ^:ii:=niri;: -^ H-r— -j-O* *- " LjS : ; 1 h i ! ’ 1 ’ i 1 ^ AJ —

U.S. EPA, Pesticide Product Label, NAMCO PINTOFUME, 11/02/1981

EPA Pesticide Factsheets

2011-04-14

... cl o-lTIII"\\iItIoI' p,," at "'-M "'Wf".SI/'IOuII:l' be toe..., 0"1 .. 9'~or .conc'~ "aoo VIda. ... bou''II ()/I ",lllls ao.j DOII'\\ (.Itr' alt.o bill.e

47 CFR 80.159 - Operator requirements of Title III of the Communications Act and the Safety Convention.

Code of Federal Regulations, 2014 CFR

2014-10-01

... accordance with Part II of Title II of the Communications Act and which has a radiotelegraph auto alarm must... as a radio officer on board U.S. ships. If the radiotelegraph station does not have an auto alarm, a...

47 CFR 80.159 - Operator requirements of Title III of the Communications Act and the Safety Convention.

Code of Federal Regulations, 2013 CFR

2013-10-01

... accordance with Part II of Title II of the Communications Act and which has a radiotelegraph auto alarm must... as a radio officer on board U.S. ships. If the radiotelegraph station does not have an auto alarm, a...

U.S. EPA, Pesticide Product Label, , 05/26/1993

EPA Pesticide Factsheets

2011-04-14

... 01 'harm •• appllc.tor toward th. upp.r corn,.". ... 1 5 II. (1.5m) • II h-om o.~~c.c'-ilr.ct ~t: •• flnl .,ray mf.t tow.rd the upp.r cor",,, of the room or ar ••. Fill ...

49 CFR 172.407 - Label specifications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... one color background of green, red or blue. (ii) White must be used for the text and class number for... Hazardous Materials Safety, Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh... markings and hazard warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For Orange—Use...

75 FR 52790 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-27

... for GEN II and GEN III Image Intensifier Tubes. SUMMARY: The U.S. Small Business Administration (SBA... Image Intensifier Tubes, Product Service Code (PSC) 5855, Night Vision Equipment, Emitted and Reflected... business GEN II and GEN III image intensifier tube manufacturers. If granted, the waiver would allow...

U.S. EPA, Pesticide Product Label, , 12/14/1982

EPA Pesticide Factsheets

2011-04-21

... l \\. , • t • ,. • • r , J L 1I.I:~dlll:;, '1\\\\ 1111111,111: .. \\1111 1>I\\II1(,:;t i~' .\\111111.11· DANGER I!armful if sw.lllow,·d. I,void I".·"lhillq v.ll"»·"

INTERSPECIES CORRELATION ESTIMATION (ICE) FOR ACUTE TOXICITY TO AQUATIC ORGANISMS AND WILDLIFE. II. USER MANUAL AND SOFTWARE

EPA Science Inventory

Asfaw, Amha, Mark R. Ellersieck and Foster L. Mayer. 2003. Interspecies Correlation Estimations (ICE) for Acute Toxicity to Aquatic Organisms and Wildlife. II. User Manual and Software. EPA/600/R-03/106. U.S. Environmental Protection Agency, National Health and Environmental Effe...

U.S. EPA, Pesticide Product Label, AGWAY MALATHION 5E, 03/14/1980

EPA Pesticide Factsheets

2011-04-21

... 1, til' ". :' I KEEP OUT OF REACH OF CHilDREN ,'!'I' .11111 1~,lI\\di jilt'! ... dtildl t'lll ,tlt • .!\\ Id~lf\\q (.11., III tll'( t' !hf' '!l(d~ 11I!1I "I! II ,lI ~ \\ ,jilt! 1 It'.: II' \\ ...

U.S. EPA, Pesticide Product Label, 5% SEVIN DUST, 11/13/1972

EPA Pesticide Factsheets

2011-04-14

... 1 , j.1 , ,! , ~ I II r 1 \\ 1 '- l) I' I .Il I l () I' ,_ II \\" , lI, qom,lI(·j'" ... 1.1111 p\\'Plhf.., ! .ll,} .I,.!,' I • . : , • 1 P "" l,'rtl;,' 1,1,.,1 11"1')' ill!TI'I) IJfl('" .. ...

U.S. EPA, Pesticide Product Label, TAT AREA FOGGER II, 06/22/1993

EPA Pesticide Factsheets

2011-04-14

... ARBA POGGBR II Kill. Pli •• , Cockroach •• , Pl~a., Sav-'footh.4 Grain B •• tl •• , 'fick., Confu •• 4 Plour B •• tl •• , Ric. • •• vil., S .. ll Plying Moth., Pil1bug. ...

The Rise of Conservatism since World War II.

ERIC Educational Resources Information Center

Carter, Dan T.

2003-01-01

Discusses the rise of the conservatism movement in the United States since World War II. States that laissez-faire capitalism and the rise of communism contributed to the popularity of conservatism in the United States. Focuses on the role of U.S. Presidents, such as Richard Nixon and Ronald Reagan. (CMK)

Early Rockets

NASA Image and Video Library

1940-01-01

In this undated file photo, probably from World War II, a V-2 rocket emerges from its camouflaged shelter. The team of German engineers and scientists who developed the V-2 came to the United States after World War II and worked for the U. S. Army at Fort Bliss, Texas and Redstone Arsenal in Huntsville, Alabama.

Correspondence Urging Bombing of Auschwitz during World War II. Teaching with Documents.

ERIC Educational Resources Information Center

Blondo, Richard A.; Schmael, Wynell Burroughs

1993-01-01

Presents a classroom lesson that utilizes primary sources about Auschwitz, the World War II Nazi concentration camp. Two letters confronting the issue of whether or not U.S. planes should bomb the camps are included. Recommends seven teaching strategies for the lesson and identifies additional resources. (CFR)

U.S. EPA, Pesticide Product Label, PRO KILL ROSE + FLORAL SPRAY, 08/12/1986

EPA Pesticide Factsheets

2011-04-21

... I..... hit. nIliliNU. If fIM 1M f ... tlt .... , IIUlit .. ,.tld .IU .,.. • 1111: 11& " •• ,,1, .1\\, ... It ..... lptilwcor"'Ir~"'~tA&I'If_ 1!fI!!'~1'J!,.~.t. IiIIiI II I 0 .. 0_ ••• ...

Electron Transfer Pathways Facilitating U(VI) Reduction by Fe(II) on Al- vs Fe-Oxides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, S. D.; Becker, U.; Rosso, K. M.

This study continues mechanistic development of heterogeneous electron transfer (ET) pathways at mineral surfaces in aquatic environments that enable the reduction U(VI) by surface-associated Fe(II). Using computational molecular simulation within the framework of Marcus Theory, our findings highlight the importance of the configurations and interaction of the electron donor and acceptor species with the substrate, with respect to influencing its electronic structure and thereby the ability of semiconducting minerals to facilitate ET. U(VI) reduction by surface-associated Fe(II) (adsorbed or structurally incorporated into the lattice) on an insulating, corundum (001) surface (α-Al2O3) occurs when proximal inner-sphere (IS) surface complexes are formed,more » such that ET occurs through a combination of direct exchange (i.e., Fe d- and U f-orbitals overlap through space) and superexchange via intervening surface oxygen atoms. U(VI) reduction by coadsorbed Fe(II) on the isostructural semiconducting hematite (α-Fe2O3) basal surface requires either their direct electronic interaction (e.g., IS complexation) or mediation of this interaction indirectly through the surface via an intrasurface pathway. Conceptually possible longer-range ET by charge-hopping through surface Fe atoms was investigated to determine whether this indirect pathway is competitive with direct ET. The calculations show that energy barriers are large for this conduction-based pathway; interfacial ET into the hematite surface is endothermic (+80.1 kJ/mol) and comprises the rate-limiting step (10–6 s–1). The presence of the IS adsorbates appears to weaken the electronic coupling between underlying Fe ions within the surface, resulting in slower intra-surface ET (10–5 s–1) than expected in the bulk basal plane. Our findings lay out first insights into donor-acceptor communication via a charge-hopping pathway through the surface for heterogeneous reduction of U(VI) by Fe(II) and help provide a basis for experimental interrogation of this important process at mineral-water interfaces.« less

Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion.

PubMed

Magnussen, Synnove Norvoll; Hadler-Olsen, Elin; Costea, Daniela Elena; Berg, Eli; Jacobsen, Cristiane Cavalcanti; Mortensen, Bente; Salo, Tuula; Martinez-Zubiaurre, Inigo; Winberg, Jan-Olof; Uhlin-Hansen, Lars; Svineng, Gunbjorg

2017-05-19

Urokinase plasminogen activator (uPA) receptor (uPAR) is up-regulated at the invasive tumour front of human oral squamous cell carcinoma (OSCC), indicating a role for uPAR in tumour progression. We previously observed elevated expression of uPAR at the tumour-stroma interface in a mouse model for OSCC, which was associated with increased proteolytic activity. The tumour microenvironment regulated uPAR expression, as well as its glycosylation and cleavage. Both full-length- and cleaved uPAR (uPAR (II-III)) are involved in highly regulated processes such as cell signalling, proliferation, migration, stem cell mobilization and invasion. The aim of the current study was to analyse tumour associated factors and their effect on uPAR cleavage, and the potential implications for cell proliferation, migration and invasion. Mouse uPAR was stably overexpressed in the mouse OSCC cell line AT84. The ratio of full-length versus cleaved uPAR as analysed by Western blotting and its regulation was assessed by addition of different protease inhibitors and transforming growth factor - β1 (TGF-β1). The role of uPAR cleavage in cell proliferation and migration was analysed using real-time cell analysis and invasion was assessed using the myoma invasion model. We found that when uPAR was overexpressed a proportion of the receptor was cleaved, thus the cells presented both full-length uPAR and uPAR (II-III). Cleavage was mainly performed by serine proteases and urokinase plasminogen activator (uPA) in particular. When the OSCC cells were stimulated with TGF-β1, the production of the uPA inhibitor PAI-1 was increased, resulting in a reduction of uPAR cleavage. By inhibiting cleavage of uPAR, cell migration was reduced, and by inhibiting uPA activity, invasion was reduced. We could also show that medium containing soluble uPAR (suPAR), and cleaved soluble uPAR (suPAR (II-III)), induced migration in OSCC cells with low endogenous levels of uPAR. These results show that soluble factors in the tumour microenvironment, such as TGF-β1, PAI-1 and uPA, can influence the ratio of full length and uPAR (II-III) and thereby potentially effect cell migration and invasion. Resolving how uPAR cleavage is controlled is therefore vital for understanding how OSCC progresses and potentially provides new targets for therapy.

Fargo-Moorhead Urban Study. Water Supply Appendix. Volume 3. Phase 2, Attachment A: Geochemical Investigations of the Old Fargo Landfill.

DTIC Science & Technology

1985-05-01

2 nHOLIES 2"IROCK LOWER LIMIT Of WASTE CELL UNDERLYING LAKE CLAYS DETAIL OF OBSERVATION WELLS INSTALLED IN 1981. FIGURE 3 V11 N8uber Depth to Botton ...ma- ~53 NOIJVAZ*I3 46 U = S. 4 9 U S .9 U I U ~! 0 I C a I i 15 ii liii I I ii. I SI I I UOLLVMdI3UUd aI,- Jo SIssot a S S aI - - a - U a -1*~ aw ...saarckJp 50 PIer.,4M-------- Chemist 11-22 I~et,D o~kota Stat* Depar’tment of H.Wh Public HealWi L-3horators I Lot tjmoer! 83-01’ 4494 g -Date Colectect

DIVWAG Model Documentation. Volume II. Programmer/Analyst Manual. Part 1.

DTIC Science & Technology

1976-07-01

that portion of the Intelligence and Control Model regulating supporting aerial fire and artillery. flight corridor: a rectangular area centered along...0.0. N N,( ON ~~ *0,U0 0 ZMN .. .6 N 6’ N N~. C4NANCy 0 -0 0 4.0 4 - 񓿀.104M 2 0 .i..i.6 C4 - - 0) 14 U.U 00 cocoa eeoc a 0iW z0 7 A 0) ;C a a . z 0...modifiers and all required data elements. (1) There are two basic rules regulating the entry of data elements when required by an order or an order modifier

Mild hydrothermal crystal growth of new uranium(IV) fluorides, Na3.13Mg1.43U6F30 and Na2.50Mn1.75U6F30: Structures, optical and magnetic properties

NASA Astrophysics Data System (ADS)

Yeon, Jeongho; Smith, Mark D.; Tapp, Joshua; Möller, Angela; zur Loye, Hans-Conrad

2016-04-01

Two new uranium(IV) fluorides, Na3.13Mg1.43U6F30 (1) and Na2.50Mn1.75U6F30 (2), were synthesized through an in situ mild hydrothermal route, and were structurally characterized by single crystal X-ray diffraction. The compounds exhibit complex crystal structures composed of corner- or edge-shared UF9 and MF6 (M=Mg, Mn) polyhedra, forming hexagonal channels in the three-dimensional framework, in which ordered or disordered divalent metal and sodium atoms reside. The large hexagonal voids contain the nearly regular M(II)F6 octahedra and sodium ions, whereas the small hexagonal cavities include M(II) and sodium ions on a mixed-occupied site. Magnetic susceptibility measurements yielded effective magnetic moments of 8.36 and 11.6 μB for 1 and 2, respectively, confirming the presence and oxidation states of U(IV) and Mn(II). The large negative Weiss constants indicate the spin gap between a triplet and a singlet state in the U(IV). Magnetization data as a function of applied fields revealed that 2 exhibits paramagnetic behavior due to the nonmagnetic singlet ground state of U(IV) at low temperature. UV-vis diffuse reflectance and X-ray photoelectron spectroscopy data were also analyzed.

Molecular principles underlying dual RNA specificity in the Drosophila SNF protein.

PubMed

Weber, Gert; DeKoster, Gregory T; Holton, Nicole; Hall, Kathleen B; Wahl, Markus C

2018-06-07

The first RNA recognition motif of the Drosophila SNF protein is an example of an RNA binding protein with multi-specificity. It binds different RNA hairpin loops in spliceosomal U1 or U2 small nuclear RNAs, and only in the latter case requires the auxiliary U2A' protein. Here we investigate its functions by crystal structures of SNF alone and bound to U1 stem-loop II, U2A' or U2 stem-loop IV and U2A', SNF dynamics from NMR spectroscopy, and structure-guided mutagenesis in binding studies. We find that different loop-closing base pairs and a nucleotide exchange at the tips of the loops contribute to differential SNF affinity for the RNAs. U2A' immobilizes SNF and RNA residues to restore U2 stem-loop IV binding affinity, while U1 stem-loop II binding does not require such adjustments. Our findings show how U2A' can modulate RNA specificity of SNF without changing SNF conformation or relying on direct RNA contacts.

Beck Depression Inventory-II: Factor Analyses with Three Groups of Midlife Women of African Descent in the Midwest, the South, and the U.S. Virgin Islands.

PubMed

Gary, Faye A; Yarandi, Hossein; Evans, Edris; Still, Carolyn; Mickels, Prince; Hassan, Mona; Campbell, Doris; Conic, Ruzica

2018-03-01

This research encompasses a factor analysis of the Beck Depression Inventory-II (BDI-II), which involves three groups of midlife women of African descent who reside in the Midwest, the South, and the U.S. Virgin Islands. The purpose of the study was to determine the factor structure of the BDI-II when administered to a sample of women aged 40-65 of African descent who reside in the three distinct geographical regions of the United States. A correlational, descriptive design was used, and 536 women of African descent were invited to participate in face-to-face interviews that transpired in community settings. Results of the factor analysis revealed a two-factor explanation. Factor one included symptoms such as punishment feelings and pessimism (cognitive), and the second factor included symptoms such as tiredness and loss of energy (somatic-affective). The application of the Beck Depression Inventory-II among the three groups of women generated specific information about each group and common findings across the groups. Knowledge gained from the research could help to guide specific intervention programs for the three groups of women, and explicate the common approaches that could be used for the three groups.

The cometary H II regions of DR 21: Bow shocks or champagne flows or both?

NASA Astrophysics Data System (ADS)

Immer, K.; Cyganowski, C.; Reid, M. J.; Menten, K. M.

2014-03-01

We present deep Very Large Array H66α radio recombination line (RRL) observations of the two cometary H II regions in DR 21. With these sensitive data, we test the "hybrid" bow shock/champagne flow model previously proposed for the DR 21 H II regions. The ionized gas down the tail of the southern H II region is redshifted by up to ~30 km s-1 with respect to the ambient molecular gas, as expected in the hybrid scenario. The RRL velocity structure, however, reveals the presence of two velocity components in both the northern and southern H II regions. This suggests that the ionized gas is flowing along cone-like shells, swept-up by stellar winds. The observed velocity structure of the well-resolved southern H II region is most consistent with a picture that combines a stellar wind with stellar motion (as in bow shock models) along a density gradient (as in champagne flow models). The direction of the implied density gradient is consistent with that suggested by maps of dust continuum and molecular line emission in the DR 21 region. The image cubes are only available as a FITS file at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/563/A39Table 2, Fig. 4, and Appendices A and B are available in electronic form at http://www.aanda.org

A Supplement to the 1995 Matched Anthropometric Database of U.S. Marine Corps Personnel: Summary Statistics

DTIC Science & Technology

1997-06-01

4.53 110.00 Maximum 4.33 Symmetry- Veta I 5.00 Symmetry- Veta I 1.20 Kurtosis- Veta II 6.70 Kurtosis- Veta II 1.40 Coeff. of Variation 33.2% Coeff of...Mean) 0.64 0.62 SE(SD) 0.02 0.62 SE(SD) 0.02 277.00 Minimum 10.91 264.00 Minimum 10.39 408.00 Maximum 16.06 379.00 Maximum 14.92 Symmetry- Veta I...0.60 Symmetry- Veta I 1.3{) Kurtosis- Veta II -0.40 Kurtosis- Veta II 0.30 Coeff. ofV ariation 4.9% Coeff. of Variation 5.2% Sample Size 4447 Sarn_ple

Extremely Low Frequency (ELF) Communications System Bio-Effects Library Development.

DTIC Science & Technology

1985-10-01

44 0 I" " I II - I-I -~i it I it LI S oit ’II La S LLa ..5 I it° it L I itS CD L C La .L- 4.-,, .-.5 c i I- i F6 ’n 1-5 ., , -j -! i h- m. it C...aII a - ma U, a"I o aao a - co 9111 aa "L . ’ * Ia a- I’ c a - ,n a , • lit a w a i a l: * -I a". a aa nC-aa a i Li a IM * a;a -a O~~c acca aZ 31 a a a

Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor.

PubMed

Vivar, Raul; Soto, Cristian; Copaja, Miguel; Mateluna, Francisca; Aranguiz, Pablo; Muñoz, Juan Pablo; Chiong, Mario; Garcia, Lorena; Letelier, Alan; Thomas, Walter G; Lavandero, Sergio; Díaz-Araya, Guillermo

2008-08-01

Cardiac fibroblasts are the major non-myocyte cell constituent in the myocardium, and they are involved in heart remodeling. Angiotensin II type 1 receptor (AT1R) mediates the established actions of angiotensin II (Ang II), and changes in its expression have been reported in cardiac fibroblasts after myocardial infarction. However, the AT1R-dependent signaling pathways involved in cardiac fibroblast death remain unknown. Using adenovirus, we ectopically expressed AT1R in cultured neonatal rat cardiac fibroblasts and investigated the role of the phospholipase (PLC)/protein kinase C (PKC) pathway on Ang II-dependent death. Ang II induced cardiac fibroblast death characterized by an early loss of mitochondrial membrane potential, increased Bax/Bcl-2 ratio, caspase-3 activation, and DNA fragmentation. All these effects were prevented by the AT1R antagonist losartan, PLC inhibitor U73122, and PKC inhibitor Gö6976. We conclude that Ang II stimulates the intrinsic apoptotic pathway in cultured cardiac fibroblasts by the AT1R/PLC/PKC signaling pathway.

Methylation of CIITA promoter IV causes loss of HLA-II inducibility by IFN-γ in promyelocytic cells

PubMed Central

De Ambrosis, Alessandro; Banelli, Barbara; Pira, Giuseppina Li; Aresu, Ottavia; Romani, Massimo; Ferrini, Silvano; Accolla, Roberto S.

2008-01-01

The human promyelocytic cell line THP-1 expresses high level of HLA class II (HLA-II) molecules after IFN-γ treatment. Here, we report a variant of THP-1 that does not express HLA-II after IFN-γ. The variant's HLA-II phenotype is constant over time in culture and it is not related to a defective IFN-γ-signalling pathway. Transfection of CIITA, the HLA-II transcriptional activator, under the control of a cytomegalovirus promoter rescues high level of HLA-DR surface expression in the variant indicating that the biosynthetic block resides in the expression of CIITA and not in the CIITA-dependent transactivation of the HLA-II promoters. Treatment of the variant with 5-azacytidine (5-aza), which inhibits CpG methylation, restores inducibility of HLA-II by IFN-γ both at transcriptional and phenotypic level and antigen presenting and processing function of the variant. DNA studies demonstrate that the molecular defect of the THP-1 variant originates from the methylation of the CIITA promoter IV. Furthermore, treatment with 5-aza produces a substantial demethylation of CIITA promoter IV and a significant increase of IFN-γ-dependent HLA-II expression in another myelomonocytic cell line, U937. Therefore hyper-methylation of CIITA promoter IV may be a relevant mechanism of epigenetic control preventing HLA-II IFN-γ inducibility in the myelomonocytic cell lineage. PMID:18829986

Monitoring complex detectors: the uSOP approach in the Belle II experiment

NASA Astrophysics Data System (ADS)

Di Capua, F.; Aloisio, A.; Ameli, F.; Anastasio, A.; Branchini, P.; Giordano, R.; Izzo, V.; Tortone, G.

2017-08-01

uSOP is a general purpose single board computer designed for deep embedded applications in control and monitoring of detectors, sensors and complex laboratory equipments. It is based on the AM3358 (1 GHz ARM Cortex A8 processor), equipped with USB and Ethernet interfaces. On-board RAM and solid state storage allows hosting a full LINUX distribution. In this paper we discuss the main aspects of the hardware and software design and the expandable peripheral architecture built around field busses. We report on several applications of uSOP system in the Belle II experiment, presently under construction at KEK (Tsukuba, Japan). In particular we will report the deployment of uSOP in the monitoring system framework of the endcap electromagnetic calorimeter.

SALT long-slit spectroscopy of CTS C30.10: two-component Mg II line

NASA Astrophysics Data System (ADS)

Modzelewska, J.; Czerny, B.; Hryniewicz, K.; Bilicki, M.; Krupa, M.; Świȩtoń, A.; Pych, W.; Udalski, A.; Adhikari, T. P.; Petrogalli, F.

2014-10-01

Context. Quasars can be used as a complementary tool to SN Ia to probe the distribution of dark energy in the Universe by measuring the time delay of the emission line with respect to the continuum. The understanding of the Mg II emission line structure is important for cosmological application and for the black hole mass measurements of intermediate redshift quasars. Aims: Knowing the shape of Mg II line and its variability allows for identifying which part of the line should be used to measure the time delay and the black hole mass. We thus aim at determining the structure and the variability of the Mg II line, as well as the underlying Fe II pseudo-continuum. Methods: We performed five spectroscopic observations of a quasar CTS C30.10 (z = 0.9000) with the SALT telescope between December 2012 and March 2014, and we studied the variations in the spectral shape in the 2700 Å-2900 Å rest frame. Results: We show that the Mg II line in this source consists of two kinematic components, which makes the source representative of type B quasars. Both components were modeled well with a Lorentzian shape, and they vary in a similar way. The Fe II contribution seems to be related only to the first (blue) Mg II component. Broad band spectral fitting instead favor the use of the whole line profile. The contribution of the narrow line region to Mg II is very low, below 2%. The Mg II variability is lower than the variability of the continuum, which is consistent with the simple reprocessing scenario. The variability level of CTS C30.10 and the measurement accuracy of the line and continuum is high enough to expect that further monitoring will allow the time delay between the Mg II line and continuum to be measured. Based on observations made with the Southern African Large Telescope (SALT) under program 2012-2-POL-003 and 2013-1-POL-RSA-002 (PI: B. Czerny).Spectra shown in Figs. 3 and 4 are only available in electronic form at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/570/A53Table 1 is available in electronic form at http://www.aanda.org

A multi-center, randomized, clinical trial comparing adhesive polyurethane foam dressing and adhesive hydrocolloid dressing in patients with grade II pressure ulcers in primary care and nursing homes

PubMed Central

2013-01-01

Background Pressure ulcers (PrUs) are ischemic wounds in the skin and underlying tissues caused by long-standing pressure force over an external bone or cartilaginous surface. PrUs are an important challenge for the overall health system because can prolong patient hospitalization and reduce quality of life. Moreover, 95% of PrUs are avoidable, suggesting they are caused by poor quality care assistance. PrUs are also costly, increasing national costs. For example, they represent about 5% of overall annual health expenses in Spain. Stages I and II PrUs have a combined prevalence of 65%. According main clinical guidelines, stage II PrUs (PrU-IIs) are usually treated by applying special dressings (polyurethane or hydrocolloid). However, little scientific evidence regarding their efficacy has been identified in scientific literature. Our aim is to assess the comparative efficacy of adhesive polyurethane foam and hydrocolloid dressings in the treatment of PrU-IIs in terms of healed ulcer after 8 weeks of follow-up. Methods/design This paper describes the development and evaluation protocol of a randomized clinical trial of two parallel treatment arms. A total of 820 patients with at least 1 PrU-II will be recruited from primary health care and home care centers. All patients will receive standardized healing procedures and preventive measures (e.g. positional changes and pressure-relieving support surfaces), following standardized procedures. The main outcome will be the percentage of wounds healed after 8 weeks. Secondary outcomes will include cost-effectiveness, as evaluated by cost per healed ulcer and cost per treated patient and safety evaluated by adverse events. Discussion This trial will address the hypothesis that hydrocolloid dressings will heal at least 10% more stage II PrUs and be more cost-effective than polyurethane foam dressings after 8 weeks. Trial registration This trial has been registered with controlled-trials number ISCRCTN57842461 and EudraCT 2012-003945-14. PMID:24359122

ECO Update Selecting and Using Reference Information in ...

EPA Pesticide Factsheets

... innnsini.h 10 'J tiTif ,»ct ti'i'e1 -jOK-ii,1 ' ,\\/« it A rii'* /•; r« i\\ 'Us itU')ilv> 'ii s.|tfi-if- inl'.r'h!" iy ^^ , n~a. ^v'<-ls 'IS .- (," i I'll jil Is- t>l C •> Ctl) ril.itlu ,*') S ...

U.S. EPA, Pesticide Product Label, COMBAT SUPERBAIT BRAND GRANULAR ANT KILLER, 05/31/2002

EPA Pesticide Factsheets

2011-04-21

... iJ:' i. •• t I \\iJe:."'" t,~d '''''jJ 'll~" -, I 1'1';"- 'I' Ul vz.~, _ , _ i L, >'.1-_;;:_ .. _ .... - I R7360-1Z J "I I ~ f ,~ii -t~~ ~ II ~ \\)\\ , l r' t 'J' j ,J£. ''j'' ~ rll ...

19 CFR 351.303 - Filing, format, translation, service, and certification of documents.

Code of Federal Regulations, 2011 CFR

2011-04-01

... to the Secretary of Commerce, Attention: Import Administration, APO/Dockets Unit, Room 1870, U.S... service list by personal service or first class mail. (ii) Service of public versions or a party's own... be by first class airmail. (ii) Request for review. In addition to the certificate of service...

77 FR 43862 - Importer of Controlled Substances; Notice of Registration; Noramco, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

... basic classes of controlled substances: Drug Schedule Phenylacetone (8501) II Opium, raw (9600) II Poppy... a controlled substance. Comments and requests for hearings on applications to import narcotic raw material are not appropriate. 72 FR 3417 (2007). DEA has considered the factors in 21 U.S.C. 823(a) and 952...

28 CFR 0.128a - General functions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... of military operations during World War II and claims of U.S. military personnel and civilian American citizens for having been held in a captured status in specified areas during World War II, the... 28 Judicial Administration 1 2011-07-01 2011-07-01 false General functions. 0.128a Section 0.128a...

28 CFR 0.128a - General functions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of military operations during World War II and claims of U.S. military personnel and civilian American citizens for having been held in a captured status in specified areas during World War II, the... 28 Judicial Administration 1 2010-07-01 2010-07-01 false General functions. 0.128a Section 0.128a...

28 CFR 0.128a - General functions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... of military operations during World War II and claims of U.S. military personnel and civilian American citizens for having been held in a captured status in specified areas during World War II, the... 28 Judicial Administration 1 2013-07-01 2013-07-01 false General functions. 0.128a Section 0.128a...

28 CFR 0.128a - General functions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... of military operations during World War II and claims of U.S. military personnel and civilian American citizens for having been held in a captured status in specified areas during World War II, the... 28 Judicial Administration 1 2014-07-01 2014-07-01 false General functions. 0.128a Section 0.128a...

28 CFR 0.128a - General functions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... of military operations during World War II and claims of U.S. military personnel and civilian American citizens for having been held in a captured status in specified areas during World War II, the... 28 Judicial Administration 1 2012-07-01 2012-07-01 false General functions. 0.128a Section 0.128a...

SPQR II: A beam-plasma interaction experiment

NASA Astrophysics Data System (ADS)

Bimbot, R.; Della-Negra, S.; Gardès, D.; Rivet, M. F.; Fleurier, C.; Dumax, B.; Hoffman, D. H. H.; Weyrich, K.; Deutsch, C.; Maynard, G.

1986-01-01

SPQR II is an interaction experiment designed to probe energy -and charge-exchange of Cn+ ions at 2 MeV/a.m.u., flowing through a fully ionized plasma column of hydrogen with nℓ=1019 e-cm-2 at T=5 eV. One expects a factor of two enhanced stopping over the cold gas case.

Doorways II: Community Counselor Reference Materials. On School-Related Gender-Based Violence Prevention and Response

ERIC Educational Resources Information Center

US Agency for International Development, 2009

2009-01-01

The Doorways training program was designed by the U.S. Agency for International Development (USAID)-funded Safe Schools Program (Safe Schools) to enable teachers, community members and students to prevent and respond to school-related gender-based violence (SRGBV). This booklet, "Doorways II: Community Counselor Reference Materials on…

75 FR 10342 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-05

... for the vessel COOL BEANS II. SUMMARY: As authorized by 46 U.S.C. 12121, the Secretary of.... SUPPLEMENTARY INFORMATION: As described by the applicant the intended service of the vessel COOL BEANS II is... added as a second vessel to our existing business, Cool Beans Cruises www.coolbeanscruises.com...

12 CFR 265.9 - Functions delegated to the Director of Division of Consumer and Community Affairs.

Code of Federal Regulations, 2011 CFR

2011-01-01

... amount specified in section 103(aa)(1)(B)(ii) of the Truth in Lending Act and § 226.32(a)(1)(ii) of... section 103(aa)(3) of that act (15 U.S.C. 1602(aa)); and (2) The amount specified in section 309(b)(1) of...

U.S. EPA, Pesticide Product Label, , 09/26/1996

EPA Pesticide Factsheets

2011-04-21

... '" I ,1· ~ ,,, 0'1'" ).J" !I"'I ""'( ~ 1'1 I' .. f ,'-" " I ,1!"I,t'l1I,J ,;1",,.· nl.1,.,. I·" f'\\Jp,',hitt 11'1 f"i f"l'" "r II"pr'<;'!I'111"ni ·.r ~'. ,. t" It, ·""j"l ,.': I '" "1,1",, I,."" ...

INNOVATIVE TECHNOLOGY VERIFICATION REPORT XRF TECHNOLOGIES FOR MEASURING TRACE ELEMENTS IN SOIL AND SEDIMENT RIGAKU ZSX MINI 11 XRF ANALYZER

EPA Science Inventory

The Rigaku ZSX Mini II (ZSX Mini II) XRF Services x-ray fluorescence (XRF) analyzer was demon-strated under the U.S. Environmental Protection Agency (EPA) Superfund Innovative Technology Evaluation (SITE) Program. The field portion of the demonstration was conducted in January 2...

U.S. EPA, Pesticide Product Label, TECHNICAL MALEIC HYDRAZIDE FOR MANUFACTURING PURPOSE, 08/06/1971

EPA Pesticide Factsheets

2011-04-19

\\I.\\I.LIC IIYI>I~:\\I.IIII': HlI.: 1':1-:\\1.\\\\('1',\\,1('1\\1\\(; 1'('I

Divorce and suicide: a time series analysis, 1933-1970.

PubMed

Stack, S

1981-01-01

The author examines the relationship between divorce and suicide using U.S. data for the period 1933-1970. The increase in the strength of the positive relationship between divorce and suicide in the period after World War II is contrasted with trends during the era of the Depression preceding World War II

World Wars at Home: U.S. Response to World War II Propaganda.

ERIC Educational Resources Information Center

Nagy, Alex

1990-01-01

Focuses on how the United States Post Office reacted to the massive influx of political propaganda, primarily from the Soviet Union, immediately prior to and during World War II. Describes how the Post Office played an active role in stopping and burning some 50 tons of incoming material. (RS)

Cost-effectiveness analysis of internet-mediated cognitive behavioural therapy for depression in the primary care setting: results based on a controlled trial

PubMed Central

Metsini, Alexandra; Madsen, Jens-Henrik; Hange, Dominique; Petersson, Eva-Lisa L; Eriksson, Maria CM; Kivi, Marie; Andersson, Per-Åke Å; Svensson, Mikael

2018-01-01

Objective To perform a cost-effectiveness analysis of a randomised controlled trial of internet-mediated cognitive behavioural therapy (ICBT) compared with treatment as usual (TaU) for patients with mild to moderate depression in the Swedish primary care setting. In particular, the objective was to assess from a healthcare and societal perspective the incremental cost-effectiveness ratio (ICER) of ICBT versus TaU at 12 months follow-up. Design A cost-effectiveness analysis alongside a pragmatic effectiveness trial. Setting Sixteen primary care centres (PCCs) in south-west Sweden. Participants Ninety patients diagnosed with mild to moderate depression at the PCCs. Main outcome measure ICERs calculated as (CostICBT−CostTaU)/(Health outcomeICBT−Health outcomeTaU)=ΔCost/ΔHealth outcomes, the health outcomes being changes in the Beck Depression Inventory-II (BDI-II) score and quality-adjusted life-years (QALYs). Results The total cost per patient for ICBT was 4044 Swedish kronor (SEK) (€426) (healthcare perspective) and SEK47 679 (€5028) (societal perspective). The total cost per patient for TaU was SEK4434 (€468) and SEK50 343 (€5308). In both groups, the largest cost was associated with productivity loss. The differences in cost per patient were not statistically significant. The mean reduction in BDI-II score was 13.4 and 13.8 units in the ICBT and TaU groups, respectively. The mean QALYs per patient was 0.74 and 0.79 in the ICBT and TaU groups, respectively. The differences in BDI-II score reduction and mean QALYs were not statistically significant. The uncertainty of the study estimates when assessed by bootstrapping indicated that no firm conclusion could be drawn as to whether ICBT treatment compared with TaU was the most cost-effective use of resources. Conclusions ICBT was regarded to be as cost-effective as TaU as costs, health outcomes and cost-effectiveness were similar for ICBT and TaU, both from a healthcare and societal perspective. Trial registration number ID NR 30511. PMID:29903785

Army Force Planning Cost Handbook (AFPCH)

DTIC Science & Technology

1982-11-01

FY82 procurement costs extracted form the POM Procurement Data Base. The weapon system unit cost definition most nearly describing these prices is...Is’ 11 il 1 ~~~~l OIL ~ JII~II It I IM u 14 1W x A I- 44 I It N IIt a-lIt IIr- a00 ~ a a I . 1 I1,35O @ I1 810R II u ILI i41 Iis LL, It-I - C I Ca...NW 4 m I IV4 AI 3 0 MI ha111 IA177 00 -. 1- 1 -. l 6 A s𔃺 ca $soon~. I _ 44 gKK4 oil ’r Ei I~~ EI I ~ a BH* .0 0 ’ 4 cp. oM I’- F 111 jIr a;I HI amm

Finite Element-Galerkin Approximation of the Eigenvalues of Eigenvectors of Selfadjoint Problems

DTIC Science & Technology

1988-07-01

l’ "k, + 1. Combining (3.20), (3.22), and the fact that I-Eh(Ak ) and Ph are orthogonal projections we have I(I-Eh(Xk,)) PhUB 5 Si (I-Eh(xk)) PhT(Ph-I...Its adjoint are equal. (3.23) implies Hf(I-Eh(1kI )Ph)u{1B - P(IPh)UIBI 5 I(I-Eh(Ak )) PhuB -< d i ii ( Ph- I )T II H B_--H,3 1(P h- I ) u liB , and

START II Frame Work

DTIC Science & Technology

1992-04-01

Colonel Richard J. Barringer , USAF The Industrial College of the Armed Forces National Defense University Fort McNair, Washington, D.C. 20319-6000 93...Executive Research Project A94 START II Frame Work Lieutenant Colonel Donald E. Belche U.S. Air Force Faculty Research Advisor Colonel Richard J. Barringer ...1,659 - 3,456 0.48 Bombers 0.11 x 4,208 = 463 - 1,100 = 0.42 Total 9,064 2,248 - 5,956 = 0.38 charts 12 and 13 28 CHART 14 U.§ IA~aI ULA QC TU R AFTER 5

The U.S.S. PUEBLO Incident, Warning Cycle.

DTIC Science & Technology

1984-09-10

11. ŕ.8 111a-25 I~U2 MICROCOP RESOUTIO TES CHART II"’D 1 963 A112 111Z’ 𔃻 1 . Defense Intelligence College c I Washington, DC 20301-6111 APPROVAL...North Korean government. Obviously both sources have a definite bias. The bias that the Pueblo crew members may have is compounded by the fact that...Pinnacle II. Therefore, they were 77 • .. mp -p - extremely confused as to what was happening. CX’ This was compounded by the fact that there was no -i

Predominant typologies of psychopathology in the United States: a latent class analysis.

PubMed

El-Gabalawy, Renée; Tsai, Jack; Harpaz-Rotem, Ilan; Hoff, Rani; Sareen, Jitender; Pietrzak, Robert H

2013-11-01

Latent class analysis (LCA) offers a parsimonious way of classifying common typologies of psychiatric comorbidity. We used LCA to identify the nature and correlates of predominant typologies of Axis I and II disorders in a large and comprehensive population-based sample of U.S. adults. We analyzed data from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (2004-2005; n = 34,653), a population-based sample of U.S. adults. We derived latent classes based on all assessed Axis I and II disorders and examined the relationship between the identified Axis I classes and lifetime psychiatric disorders and suicide attempts, and physical and mental health-related quality of life. A four-class solution was optimal in characterizing predominant typologies of both Axis I and II disorders. For Axis I disorders, these included low psychopathology (n = 28,935, 84.0%), internalizing (n = 3693, 9.9%), externalizing (n = 1426, 4.5%), and high psychopathology (n = 599, 1.6%) classes. For Axis II disorders, these included no/low personality disorders (n = 31,265, 90.9%), obsessive/paranoid (n = 1635, 4.6%), borderline/dysregulated (n = 1319, 3.4%), and highly comorbid (n = 434, 1.1%) classes. Compared to the low psychopathology class, all other Axis I classes had significantly increased odds of mental disorders, elevated Axis II classes, suicide attempts and poorer quality of life, with the high psychopathology class having the overall highest rates of these correlates, with the exception of substance use disorders. Compared to the low psychopathology class, the internalizing and externalizing classes had increased rates of mood and anxiety disorders, and substance use disorders, respectively. Axis I and II psychopathology among U.S. adults may be best represented by four predominant typologies. Characterizing co-occurring patterns of psychopathology using person-based typologies represents a higher-order classification system that may be useful in clinical and research settings. Published by Elsevier Ltd.

Inner and outer star forming regions over the disks of spiral galaxies. I. Sample characterization

NASA Astrophysics Data System (ADS)

Rodríguez-Baras, M.; Díaz, A. I.; Rosales-Ortega, F. F.; Sánchez, S. F.

2018-01-01

Context. The knowledge of abundance distributions is central to understanding the formation and evolution of galaxies. Most of the relations employed for the derivation of gas abundances have so far been derived from observations of outer disk H ii regions, despite the known differences between inner and outer regions. Aims: Using integral field spectroscopy (IFS) observations we aim to perform a systematic study and comparison of two inner and outer H ii regions samples. The spatial resolution of the IFS, the number of objects and the homogeneity and coherence of the observations allow a complete characterization of the main observational properties and differences of the regions. Methods: We analyzed a sample of 725 inner H ii regions and a sample of 671 outer H ii regions, all of them detected and extracted from the observations of a sample of 263 nearby, isolated, spiral galaxies observed by the CALIFA survey. Results: We find that inner H ii regions show smaller equivalent widths, greater extinction and luminosities, along with greater values of [N ii] λ6583/Hα and [O ii] λ3727/[O iii] λ5007 emission-line ratios, indicating higher metallicities and lower ionization parameters. Inner regions have also redder colors and higher photometric and ionizing masses, although MionMphot is slighty higher for the outer regions. Conclusions: This work shows important observational differences between inner and outer H ii regions in star forming galaxies not previously studied in detail. These differences indicate that inner regions have more evolved stellar populations and are in a later evolution state with respect to outer regions, which goes in line with the inside-out galaxy formation paradigm. Table 4 is only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/609/A102

Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells

PubMed Central

Santra, Manoranjan; Santra, Sutapa; Buller, Ben; Santra, Kastuv; Nallani, Ankita; Chopp, Michael

2011-01-01

Analysis of Affymetrix Probe data from glioma patient samples in conjuction with patient Kaplan-Meier Survival Plot indicate that expression of a glioma suppressor gene doublecortin (DCX) favors glioma patient survival. From neurosphere formation in culture, Time-Lapse Microscopy video recording and tumor xenograft, we show that DCX synthesis significantly reduces self-renewal of brain tumor stem cells (BTSCs) in human primary glioma (YU-PG, HF66) cells from surgically-removed human glioma specimens and U87 cells in vitro and in vivo. Time-Lapse Microscopic video recording revealed that double transfection of YU-PG, HF66 and U87 cells with DCX and neurabin II caused incomplete cell cycle with failure of cytokinesis, i.e. endomitosis by dividing into three daughter cells from one mother BTSC. Activation of c-jun NH2-terminal kinase 1 (JNK1) after simvastatin (10nM) treatment of DCX+neurabin II+ BTSCs from YU-PG, HF66 and U87 cells induced terminal differentiation into neuron-like cells. TUNEL staining data demonstrated that JNK1 activation also induced apoptosis only in double transfected BTSCs with DCX and neurabin II, but not in single transfected BTSCs from YU-PG, HF66 and U87 cells. Western blot analysis showed that procaspase-3 was induced after DCX transfection and activated after simvastatin treatment in YU-PG, HF66 and U87 BTSCs. Sequential immunoprecipitation and Western blot data revealed that DCX synthesis blocked protein phosphatase-1 (PP1)/caspase-3 protein-protein interaction and increased PP1-DCX interaction. These data demonstrate that DCX synthesis induces apoptosis in BTSCs via a novel JNK1/neurabin II/DCX/PP1/caspase-3 pathway. PMID:21477071

Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells.

PubMed

Santra, Manoranjan; Santra, Sutapa; Buller, Ben; Santra, Kastuv; Nallani, Ankita; Chopp, Michael

2011-07-01

Analysis of microarray probe data from glioma patient samples, in conjunction with patient Kaplan-Meier survival plots, indicates that expression of a glioma suppressor gene doublecortin (DCX) favors glioma patient survival. From neurosphere formation in culture, time-lapse microscopic video recording, and tumor xenograft, we show that DCX synthesis significantly reduces self-renewal of brain tumor stem cells (BTSC) in human primary glioma (YU-PG, HF66) cells from surgically removed human glioma specimens and U87 cells in vitro and in vivo. Time-lapse microscopic video recording revealed that double transfection of YU-PG, HF66, and U87 cells with DCX and neurabin II caused incomplete cell cycle with failure of cytokinesis, that is, endomitosis by dividing into three daughter cells from one mother BTSC. Activation of c-jun NH2-terminal kinase 1 (JNK1) after simvastatin (10 nM) treatment of DCX(+) neurabin II(+) BTSC from YU-PG, HF66, and U87 cells induced terminal differentiation into neuron-like cells. dUTP nick end labeling data indicated that JNK1 activation also induced apoptosis only in double transfected BTSC with DCX and neurabin II, but not in single transfected BTSC from YU-PG, HF66, and U87 cells. Western blot analysis showed that procaspase-3 was induced after DCX transfection and activated after simvastatin treatment in YU-PG, HF66, and U87 BTSC. Sequential immunoprecipitation and Western blot data revealed that DCX synthesis blocked protein phosphatase-1 (PP1)/caspase-3 protein-protein interaction and increased PP1-DCX interaction. These data show that DCX synthesis induces apoptosis in BTSC through a novel JNK1/neurabin II/DCX/PP1/caspase-3 pathway. © 2011 Japanese Cancer Association.

Special Data Collection System (SDCS) Northern Sinkiang Province, China, 20 March 1976

DTIC Science & Technology

1976-05-28

i /1^^ rAvv ^^y^-^^- ■O^^VWVVA^V^^A U^nrJ\\/^\\/\\A/\\l^/^V/^ 13C 128.’» TIME 04« 42140.0 i ...RFClPlENT". CATAL^ i ’’. N’/MflFP B CONTBACT O» GRANT MuMBf.B^, F^86^6-74-C-^,)13 / II CONTROLLING OEElCE NAME AND...mh.irmi I tnltfd In Block 30, II dlllmrtnl Irom Roporl) IB SUPPLEMENTARY NOTES 19 KEY WORDS (Conllnum on rovtf »Id» II nocmttmry mnd Idtnllly

TET Offensive II Field Force Vietnam After Action Report 31 January - 18 February 1968

DTIC Science & Technology

1968-03-01

and the 5th VC Division. V During this same period of time there were no majur shifts in ARVN forces . However III Corps shifted three...8217-".•: ’ ’SSIFJED U.S. ARMY. VIETNAM. II FIELD FORCE . TET OFFENSIVE II FIELD FORCE VIETNAM AFTER ACTION REPORT, 31 JANUARY-18 FEB- RUARY 1968...H FIELD FORCE VIETNAM AFTER ACTION REPORT 31 January-18 February 1968 RECORD K0- ! FlSjl fi-.-A-,>-•: it tT*\\ : *si h s» -wP Mr-, £< St

The Use of Music in Labor: Pain Perception

DTIC Science & Technology

1991-01-01

AD-A267 985liiiiiii ii ii iii lillinl lJtlflllllIi 1\\k . Music in Labor DTIC43.t ELECTE wN AUGt 1 1993UThe Use of Music in Labor: A C1 Pain...Perception Kathy Jo Keever Patricia A. Shepherd AFIT/Georgetown University School of Nursing Running head: MUSIC IN LABOR Ap9i" "r85T16x• ~ ;u~c r~eca _W...FUNDING NUMBERS The Use of Music in Labor: Pain Perception 6. AUTHOR(S) 1st Lt Kathy Keever Capt Patricia Shepherd PERFORMING ORGANIZATION NAME(S) AND

Guidelines for Conducting a Training Effectiveness Evaluation (TEE). Volume 2. Data Collector’s Manual

DTIC Science & Technology

1985-02-01

D : ■>■■ ’•.’.’. Research Product 85-15 Guidelines for Conducting a Training Effectiveness Evaluation (TEE) Volume II: Data...CONDUCTING A TRAINING EFFECTIVENESS EVALUATION (TEE) VOLUME II: DATA COLLECTOR’S MANUAL 1 t. TV*CO» READ INSTRUCTIONS BEFORE COMWLETWC FORM I...2Q263739A793 3227 52A M. COMTAOLUMQ O’ttCC RAMC AND ADO* CSS Co—and ant U.S. Army Air Defense School ATTN: ATSA-TDI, Ft. Bliss, TX II. RCRORf OATC

Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II.

PubMed

Jeske, Y W A; So, A; Kelemen, L; Sukor, N; Willys, C; Bulmer, B; Gordon, R D; Duffy, D; Stowasser, M

2008-04-01

1. There are two types of familial hyperaldosteronism (FH): FH-I and FH-II. FH-I is caused by a hybrid CYP11B1/CYP11B2 gene mutation. The genetic cause of FH-II, which is more common, is unknown. Adrenal hyperplasia and adenomas are features. We previously reported linkage of FH-II to a approximately 5 Mb region on chromosome 7p22. We subsequently reported finding no causative mutations in the retinoblastoma-associated Kruppel-associated box gene (RBaK), a candidate at 7p22 involved in tumorigenesis and cell cycle control. 2. In the current study we investigated RBaK regulatory regions and two other candidate genes: postmeiotic segregation increased 2 (PMS2, involved in DNA mismatch repair and tumour predisposition) and guanine nucleotide-binding protein alpha-12 (GNA12, a transforming oncogene). 3. The GNA12 and PMS2 genes were examined in two affected (A1, A2) and two unaffected (U1, U2) subjects from a large 7p22-linked FH-II family (family 1). No mutations were found. 4. The RBaK and PMS2 distal promoters were sequenced to -2150 bp from the transcription start site for RBaK and-2800 bp for PMS2. Five unreported single nucleotide polymorphisms (SNPs) were found in subjects A1, A2 but not in U1 or U2; A(-2031 bp)T, T(-2030 bp)G, G(-834 bp)C, C(-821 bp)G in RBaK and A(-876 bp)G in PMS2. Additional affected and unaffected subjects from family 1 and from two other 7p22-linked FH-II families and 58 unrelated normotensive control subjects were genotyped for these SNPs. 5. The five novel SNPs were found to be present in a significant proportion of normotensive controls. The four RBaK promoter SNPs were found to be in linkage disequilibrium in the normal population. The RBaK promoter (-)2031T/2030G/834C/821T allele was found to be in linkage disequilibrium with the causative mutation in FH-II family 1, but not in families 2 and 3. The PMS2 promoter (-)876G allele was also found to be linked to affected phenotypes in family 1. 6. The RBaK and PMS2 promoter SNPs alter the binding sites for several transcription factors. Although present in the normal population, it is possible that the RBaK (-)2031T/2030G/834C/821T and PMS2 (-)876G alleles may have functional roles contributing to the FH-II phenotype in family 1.

Surveillance Report. Stage I. Dissected Motor/Propellant Motor Number 0012029.

DTIC Science & Technology

1986-02-01

D v- 040404oW 004 z UP NIJWJU V)3 IUW c )w 0 4 4c - j u okow’po’o(’ 1 z ~ fil W CD 0 W a S U zu 0 0 0 V) It...8217 0006000 c~ %2 1- . II 4 U 4 00.0000 0 u 111 z’WJJWU * .’-~*neoO17 0N Ci0c2. J 000 M -W *co 0f U13 e.J to W nC% 41, 3 x CL, D c’J 0 InI~ OWW.L)W)~ CDzz0...8217’)’ ) 4 4 Z( 0~ Z 4+ + 44 4-~O(’ z II .4 d d 9 4. V) A uu iu Uu i I 30- (n : - 7 C - , M 0 vC 0 000t l0% ttl xn *U WWWNUaWW -z v r w 4

Lower neurocognitive function in U-2 pilots

PubMed Central

Tate, David F.; Wood, Joe; Sladky, John H.; McDonald, Kent; Sherman, Paul M.; Kawano, Elaine S.; Rowland, Laura M.; Patel, Beenish; Wright, Susan N.; Hong, Elliot; Rasmussen, Jennifer; Willis, Adam M.; Kochunov, Peter V.

2014-01-01

Objective: Determine whether United States Air Force (USAF) U-2 pilots (U2Ps) with occupational exposure to repeated hypobaria had lower neurocognitive performance compared to pilots without repeated hypobaric exposure and whether U2P neurocognitive performance correlated with white matter hyperintensity (WMH) burden. Methods: We collected Multidimensional Aptitude Battery–II (MAB-II) and MicroCog: Assessment of Cognitive Functioning (MicroCog) neurocognitive data on USAF U2Ps with a history of repeated occupational exposure to hypobaria and compared these with control data collected from USAF pilots (AFPs) without repeated hypobaric exposure (U2Ps/AFPs MAB-II 87/83; MicroCog 93/80). Additional comparisons were performed between U2Ps with high vs low WMH burden. Results: U2Ps with repeated hypobaric exposure had significantly lower scores than control pilots on reasoning/calculation (U2Ps/AFPs 99.4/106.5), memory (105.5/110.9), information processing accuracy (102.1/105.8), and general cognitive functioning (103.5/108.5). In addition, U2Ps with high whole-brain WMH count showed significantly lower scores on reasoning/calculation (high/low 96.8/104.1), memory (102.9/110.2), general cognitive functioning (101.5/107.2), and general cognitive proficiency (103.6/108.8) than U2Ps with low WMH burden (high/low WMH mean volume 0.213/0.003 cm3 and mean count 14.2/0.4). Conclusion: In these otherwise healthy, highly functioning individuals, pilots with occupational exposure to repeated hypobaria demonstrated lower neurocognitive performance, albeit demonstrable on only some tests, than pilots without repeated exposure. Furthermore, within the U2P population, higher WMH burden was associated with lower neurocognitive test performance. Hypobaric exposure may be a risk factor for subtle changes in neurocognition. PMID:25008397

Origin of diffuse C II 158 micron and Si II 35 micron emission in the Carina nebula

NASA Astrophysics Data System (ADS)

Mizutani, M.; Onaka, T.; Shibai, H.

2004-08-01

We present the results of mapping observations with ISO of [O I] 63 μm, 145 μm, [N II] 122 μm, [C II] 158 μm, [Si II] 35 μm, and H_2 9.66 μm line emissions for the Carina nebula, an active star-forming region in the Galactic plane. The observations were made for the central 40 arcmin × 20 arcmin area of the nebula, including the optically bright H II region and molecular cloud lying in front of the ionized gas. Around the center of the observed area is the interface between the H II region and the molecular cloud which creates a typical photodissociation region (PDR). The [C II] 158 μm emission shows a good correlation with the [O I] 63 μm emission and peaks around the H II-molecular region interface. The correlated component has the ratio of [C II] 158 μm to [O I] 63 μm of about 2.8. We estimate from the correlation that about 80% of [C II] emission comes from the PDR in the Carina nebula. The photoelectric heating efficiency estimated from the ratio of the ([C II] 158 μm + [O I] 63 μm) intensity to the total far-infrared intensity ranges from 0.06 to 1.2%. [O I] 145 μm is detected marginally at 10 positions. The average ratio of [O I] 145 μm to [O I] 63 μm of these positions is about 0.09 ± 0.01 and is larger than model predictions. The observed [C II] 158 μm to [O I] 63 μm ratio indicates a relatively low temperature ( <500 K) of the gas, while the large [O I] 145 μm to 63 μm ratio suggests a high temperature (˜ 1000 K). This discrepancy cannot be accounted for consistently by the latest PDR model with the efficient photoelectric heating via polycyclic aromatic hydrocarbons (PAHs) even if absorption of [O I] 63 μm by foreground cold gas is taken into account. We suggest that absorption of [C II] 158 μm together with [O I] 63 μm by overlapping PDRs, in which the heating via PAHs is suppressed due to the charge-up effect, may resolve the discrepancy. Quite strong [Si II] 35 μm emission has been detected over the observed area. It shows a good correlation with [N II] 122 μm, but the correlation with [O I] 63 μm is very weak, indicating that [Si II] 35 μm comes mainly from the diffuse ionized gas rather than the PDR. The ratio of [Si II] 35 μm to [N II] 122 μm is about 8 and Si of about 50% of the solar abundance relative to N should be present in the gas phase. The present results suggest that efficient dust destruction takes place and a large fraction of Si returns to the gas in the Carina star-forming region. Based on observations with ISO, an ESA project with instruments funded by ESA Member States (especially the PI countries: France, Germany, The Netherlands and the United Kingdom) and with the participation of ISAS and NASA. Table 2 is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/423/579

Geographic List of Prime Contract Awards. Oct 92-Sep 93. FY 93. (Amos, Kentucky-Montgomery County, Maryland). Part 6

DTIC Science & Technology

1994-03-01

r 11 c I0-eJI C1 31 00000P0) 0 (icc C) Cr) M 0 W( D(DE DW D0)o I o0)0 II.’I1)cc jinI 11 ) C\\LC\\m NA NI C111 Mr (’*4 Y MCJMMMMM (nr (YiC ) (ici MCici...0 00 0 0 III0-Ic14򒰌 OW 000 00 00 000 00 00 000> 00 0 00 11 1 l-4N II 1 N N, NN N 4 N NNN > II 10-i- 11 >- z co11111 - I\\ jINI ,-t 0 11 N N 00 Nc 4ɚ...I 0011C U.L 11 c I caoc II 00 11 E I Gao 0r, 1 -- -I .- ---- -- - - - - - - -- ----- 114- I COLD4l II 000000000000000000000000000000000000000000 00 1

Type II solar radio bursts, interplanetary shocks, and energetic particle events

NASA Technical Reports Server (NTRS)

Cane, H. V.; Stone, R. G.

1984-01-01

Using the ISEE-3 radio astronomy experiment data 37 interplanetary (IP) type II bursts have been identified in the period September 1978 to December 1981. These events and the associated phenomena are listed. The events are preceded by intense, soft X ray events with long decay times (LDEs) and type II and/or type IV bursts at meter wavelengths. The meter wavelength type II bursts are usually intense and exhibit herringbone structure. The extension of the herringbone structure into the kilometer wavelength range results in the occurrence of a shock accelerated (SA) event. The majority of the interplanetary type II bursts are associated with energetic particle events. These results support other studies awhich indicate that energetic solar particles detected at 1 A.U. are generated by shock acceleration. From a preliminary analysis of the available data there appears to be a high correlation with white light coronal transients.

Cubic and Rhombohedral Heterobimetallic Networks Constructed from Uranium, Transition Metals, and Phosphonoacetate. New Methods for Constructing Porous Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alsobrook, Andera N.; Hauser, B. G.; Hupp, Joseph T.

2010-11-01

Four heterobimetallic U(VI)/M(II) (M = Mn, Co, Cd) carboxyphosphonates have been synthesized. M 2[(UO 2) 6(PO 3CH 2CO 2) 3O 3(OH)(H 2O) 2]·16H 2O (M = Mn(II), Co(II), and Cd(II)) adopt cubic three-dimensional network structures with large cavities approximately 16 Å in diameter that are filled with co-crystallized water molecules. [Cd 3(UO 2) 6(PO 3CH 2CO 2) 6(H 2O) 13]·6H 2 O forms a rhombohedral channel structure with hydrated Cd(II) within the channels. The cubic compound (Co) displays differential gas absorption with a surface area for CO 2 uptake of 40 m 2 g -1 at 273 K, and nomore » uptake of N 2 at 77 K.« less

Isolation and characterisation of mRNA encoding the salmon- and chicken-II type gonadotrophin-releasing hormones in the teleost fish Rutilus rutilus (Cyprinidae).

PubMed

Penlington, M C; Williams, M A; Sumpter, J P; Rand-Weaver, M; Hoole, D; Arme, C

1997-12-01

The complementary DNAs (cDNA) encoding the [Trp7,Leu8]-gonadotrophin-releasing hormone (salmon-type GnRH; sGnRH:GeneBank accession no. u60667) and the [His5,Trp7,Tyr8]-GnRH (chicken-II-type GnRH; cGnRH-II: GeneBank accession no. u60668) precursor in the roach (Rutilus rutilus) were isolated and sequenced following reverse transcription and rapid amplification of cDNA ends (RACE). The sGnRH and cGnRH-II precursor cDNAs consisted of 439 and 628 bp, and included open reading frames of 282 and 255 bp respectively. The structures of the encoded peptides were the same as GnRHs previously identified in other vertebrates. The sGnRH and cGnRH-II precursor cDNAs, including the non-coding regions, had 88.6 and 79.9% identity respectively, to those identified in goldfish (Carassius auratus). However, significant similarity was not observed between the non-coding regions of the GnRH cDNAs of Cyprinidae and other fish. The presumed third exon, encoding partial sGnRH associated peptide (GAP) of roach, demonstrated significant nucleotide and amino acid similarity with the appropriate regions in the goldfish, but not with other species, and this may indicate functional differences of GAP between different families of fish. cGnRH-II precursor cDNAs from roach had relatively high nucleotide similarity across this GnRH variant. Cladistic analysis classified the sGnRH and cGnRH-II precursor cDNAs into three and two groups respectively. However, the divergence between nucleotide sequences within the sGnRH variant was greater than those encoding the cGnRH-II precursors. Consistent with the consensus developed from previous studies, Northern blot analysis demonstrated that expression of sGnRH and cGnRH-II was restricted to the olfactory bulbs and midbrain of roach respectively. This work forms the basis for further study on the mechanisms by which the tapeworm, Ligula intestinalis, interacts with the pituitary-gonadal axis of its fish host.

Pulsed Laser Device Development Program. Volume 3. ABEL II (Air- Breathing Electric Laser II) Small-Scale Flow Test Report

DTIC Science & Technology

1981-06-01

about 0.18 x 104 f or X 5260 A. 4.3 EFFECT OF FLOW PLATE In this series of experiments, we studied the effect of a screen positioned over the orifice... 104 Ŕ 0 A -03 -0.2 -0.1 0 0.1 0.2 0.3 RaU1 U2 WR I+u 2 J9683 Figure 14 Effect of Shear on Phase Aberration; = 5260 .• 42 -AVCO EVERETT in Fiue1; 56...US Army Missile Command Redstone Arsenal, AL 35898 Attn: DRSMI- RHB , Dr. T.A. Roberts RHE, Mr. J.C. Walters - RHC, Mr. K. Smith RHC, Mr. Myron Cole

Sortie Duration and Helicopter Component Failures (an Empirical Study).

DTIC Science & Technology

1983-05-01

tD u* >0 I- . I : * >+0 .LJW ] 4 " * 0 0 0 (J * I L) C t > 0 .4-U. f> zJ, 1C I * >I >0 u~C. - - 0 0 0 .’ ZZ11- /- 0...o II -i I C! > 0 I go * - I 0 > 0 > > > 0 I 0 >go 7, I £0 - - f "- I10 SC) Z + > 0 * > I I > 0 >2 * >0 > - * +> (I) >O tD > O S> -0 + uic + >o - >1...8217,1 - C- o I * -CI II)- + o 1 10 -7 i C, C I ’ 1~ t JAJ I 10 I I: : IC , .. ,- .,. C.,, , , . : - ’ I,. . . . , - . . .... .1 .1 1 2it -C 4. )0 n 0

Language Manual for Use with Ideographic Composing Machines Models AR816 and AR3L. Volume II. Master List of Characters.

DTIC Science & Technology

1970-02-09

U CMI I 14 499 CP 3,263.3 SR II .i~~.., BSD8DPB8 BOS 3M )3. U P K 216 4 GEN 35 3.98 CM 11 IC HYO(N N 2943 3P 13144 ST 13. P XIAN ’. K 2106 CS 203 R...38334 SR 6 P XIA (14 K 1353 CS 1523 K 75 BOGEE8 GQ 3M 8 W P N 1)86 4 35 1396 CM 8 K PANG N 3P 36913 ST 8 P FANG1 K 746 CS 1524 N 75 U FANC .1 H 183,0

Cooperative Security in Northeast Asia. A China-Japan-South Korea Coalition Approach

DTIC Science & Technology

1990-01-01

14)1) cSidllishl~ilg a sinIIdI4.i lis15 o I S treg (ional sccuh ii Of , orts. Of) licccss’i1 . scYcrdI I I(l IWtV \\ "ItIg"t CalV(Iiigi CM-t iaua tics...hoiliogtimi A -11 1)jiit(11]-(.( ( dl 0III 1Kmi (2 vI rl cnrl(111 ii(12 Oii~ f th an IiU 11(h2ld tid(2. I ilc - historic111es kt~Ii .ts he~ MSiiiitC...See- ietiarvN oF[ State \\( Ilcs (tIl (Iili 1101 Hiclittio the Korean P~eninisula inl (ItfIiniti ’s g’lobal sceur i initere’sts, ledl to the Soviet- land

76 FR 39443 - National Environmental Policy Act; Santa Susana Field Laboratory

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-06

... analysis and consultation. These include surveys for wildlife, critical habitat, rare plants, wetlands, and..., Bravo, Coca, and Delta. Area II and the LOX Plant portion of Area I were acquired by NASA from the U.S... Area II and a portion of Area I (LOX Plant) of SSFL. As part of the environmental review process...

Promoting the "Public Welfare" in Wartime: Stanford University during World War II

ERIC Educational Resources Information Center

Dorn, Charles

2005-01-01

As with many U.S. colleges and universities during World War II, Stanford University responded to the demands of mobilization by increasing its commitment to technical training and adopting a defense research agenda. In a striking departure from this national trend, however, Stanford also established its School of Humanities in 1942. By examining…

77 FR 5849 - Manufacturer of Controlled Substances; Notice of Registration

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-06

... October 7, 2011, 76 FR 62449, Cambrex Charles City, Inc., 1205 11th Street, Charles City, Iowa 50616, made... Sufentanil (9740) II Fentanyl (9801) II The company will manufacture the listed controlled substances in bulk... factors in 21 U.S.C. 823(a) and determined that the registration of Cambrex Charles City, Inc. to...

Doorways II: Community Counselor Training Manual on School-Related Gender-Based Violence Prevention and Response

ERIC Educational Resources Information Center

US Agency for International Development, 2009

2009-01-01

The Doorways training program was designed by the U.S. Agency for International Development (USAID)-funded Safe Schools Program (Safe Schools) to enable teachers, community members and students to prevent and respond to school-related gender-based violence (SRGBV). Doorways II was designed for community counselors to prevent and respond to…

U.S. EPA, Pesticide Product Label, B-145 WEED KILLER, 10/04/1991

EPA Pesticide Factsheets

2011-04-19

... 1 I ," ,. 1 l , .' I I .. " ~ " t ."\\ I ~ i' t I_ ~" I Vft Ii"q I~I rllll!)11 /,,:. 11t.

76 FR 34732 - Privacy Act of 1974; Department of Homeland Security/National Protection and Programs Directorate...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-14

... and Lawful Permanent Residents i. Full name; ii. Date of birth; and iii. Citizenship or Gender. b. Non-U.S. persons i. Full name; ii. Date of birth; iii. Citizenship; and iv. Passport information and/or...; c. Gender; d. Citizenship; and e. Redress Number. (5) DHS could collect additional identifying...

Radio and the Black Soldier during World War II.

ERIC Educational Resources Information Center

Meckiffe, Donald; Murray, Matthew

1998-01-01

Contributes to scholarship on the representation of race in the electronic media. Traces particular social, political, and institutional pressure influencing the production of the figure of the black soldier in U.S. radio during World War II. Shows how it served to varying degrees the immediate interests of the black press, the federal government,…

Center for Naval Analyses Annual Report 1984.

DTIC Science & Technology

1984-01-01

advice about new the development and evaluation of areas for fruitful work. tactical, operational, and strategic concepts. On behalf of the Board of...iuftttniestratimi iriii.r~ent.i~e~ tlld~ IiLysiil Imt p rceerenlt serxcrcs. Publications, Icccenprc’.es j citr ,eia U .’lrltV, fir cccl an v ii ice he tal anI tinde

U.S. EPA, Pesticide Product Label, RED TORPEDO USE-AS-IS RAT KILLER, 12/14/1967

EPA Pesticide Factsheets

2011-04-21

... ".dh('t'p an \\,lill\\(,ITlllJ'tt'd ,1Ippl~ of 11:111 1'11' nl.; at It'.I;t II) Ii:l\\';, fll) mil" ;\\1 it-:l"\\ 1:) '1:1:,', If kli~ I)('crill\\l'-; >(ur. m()ld~' 't!' Ot!kr\\":l'-jlOI;Cd, it .. ...

U.S. EPA, Pesticide Product Label, CREOLE BRAND SUPERFINE CONDITIONED DUSTING SULFUR, 02/05/1973

EPA Pesticide Factsheets

2011-04-13

... "~, .11 ihj· 1'., .. f, I,,· ) \\ f 1'1 I' ,t) II \\Hh\\,\\TF1> '1IIf' 1)!I' \\' I'. ,\\!hl \\IIh.l-.\\ '\\lJ ()l'lIlH \\\\.lrlll'\\·1\\ ... i, fl: f: , . I (" I r.., I', r~ 'n . )' t,tf1, r ' ...

Oxidant Selection for the Treatment of Manganese (II), Iron (II), and Arsenic (III) in Groundwaters

EPA Science Inventory

In order to comply with the United States Environmental Protection Agency’s (U.S. EPA’s) arsenic standard and the manganese and iron secondary maximum contaminant levels (MCLs) in water (10µg/L, 50µg/L, and 300µg/L, respectively), many Midwestern water utilities must add a strong...

U.S. EPA, Pesticide Product Label, L & S ANT & ROACH SPRAY AN INDUSTRIAL & HOUSEHOLD RESIDUAL INSECTICIDE, 07/10/1969

EPA Pesticide Factsheets

2011-04-19

... < ·~".tt()rp'l ~ .rl j:. !111~J.+·': 1 /' •.. r ~ I ~'j l, .'ft'~ rl' tI". ( \\ .rI.~J dp. JONES EXTERMINATING (0. r ~ : !; ·ii If "T~}f ['I ., ' 1'( ( l q , I • r '. I -.' \\, I 1, II • III , ...

Genetic improvement of U.S. soybean in Maturity Groups II, III, and IV

USDA-ARS?s Scientific Manuscript database

Soybean [Glycine max (L.) Merr.] improvement via plant breeding has been critical for the success of the crop. The objective of this study was to quantify genetic change in yield and other traits that occurred over the past 80 years of North American soybean breeding in maturity groups (MGs) II, III...

U.S. EPA, Pesticide Product Label, FERTI-LOME GYPSY MOTH, JAPANESE BEETLE AND PINE MOTH KILLER, 06/08/1984

EPA Pesticide Factsheets

2011-04-14

,'1 •.• 1I11!~: ~ . jqi, ,'III ~~1\\, J.., I! ~"'.h \\1·,." in t (1 II i I ,'( t r ... -: Il t: .11 III', I"",', 1.11 i ,., .'1" I. '\\', IY' r " \\I .... tll I,', ,' It-, "I"'!.'lel' ',."1 b .1 II,. ...

German Women in the Five New Lander: Employment and Entrepreneurship

DTIC Science & Technology

1992-12-01

AD-A259 101 GERMAN WOMEN IN THE FIVE NEW LANDER: EMPLOYMENT AND ENTREPRENEURSHIP * DTIC_S EECTE = EC31992 J Maella Blalock Lohman Ai U Submitted to...iv II II TABLE OF CONTENTS CHAPTER 1: Introduction ................................ 1 Women Entrepreneurs ...................... 4 Entrepreneurship ...and Family Life ......... 19 Entrepreneurship in the GDR ............. 25 CHAPTER 3: Present Conditions ......................... 31 Unemployment and

Israeli-Arab Negotiations: Background, Conflicts, and U.S. Policy

DTIC Science & Technology

2010-01-29

50 Sharm al Shaykh Memorandum...Egypt’s President Mubarak, and Jordan’s King Abdullah II met in Sharm al Shaykh, Egypt. Abbas called on Olmert to start serious negotiations. Olmert only...conclave.206 Sharm al Shaykh Memorandum (Also called Wye II.) Signed on September 4, 1999.207 Israeli Prime Minister Barak and PA Chairman Arafat agreed

Israeli-Arab Negotiations: Background, Conflicts, and U.S. Policy

DTIC Science & Technology

2008-10-30

39 Wye River Memorandum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39 Sharm al Shaykh Memorandum...President Mubarak, and Jordan’s King Abdullah II met in Sharm al Shaykh, Egypt. Abbas called on Olmert to start serious negotiations to establish a... Sharm al Shaykh Memorandum. (Also called Wye II.) Signed on September 4, 1999.117 Israeli Prime Minister Barak and PA Chairman Arafat agreed to

Empowering the World War II Native American Veteran: Postwar Civil Rights.

ERIC Educational Resources Information Center

Franco, Jere

1993-01-01

"Promised" by the Dawes Act of 1887, U.S. citizenship was finally granted to all Native Americans in 1924 and reaffirmed in 1940 as World War II and military service loomed. Nevertheless, six states prevented Indians from voting until the 1950s. Since then, Indian political participation and voting power have grown, particularly in some western…

U.S. EPA, Pesticide Product Label, MYCOTROL ES, 11/13/2008

EPA Pesticide Factsheets

2011-04-21

... rL"plr~iI,'r Ille·l·tillg .\\iII)SI I sl~llldards nfa( kast R-'):'i or Pl)5. Rq)~alCd L'XpOSUI\\' III hit!h l'PllcL'llIr:lliull:' pI" 1l1l .... Ttihl:!I 111"1)IL'II1:-. (:llll';ltl:-'l' alh . ...

U.S. EPA, Pesticide Product Label, TDC DICOFOL 4E, 02/19/1982

EPA Pesticide Factsheets

2011-04-21

... kJI ~ ...-I ~ ... M<1 ~ IIrf'Ie(II.-cI -- roc D«X>fOt '·E CWI be ~ 8IIOnI or 'tII"Ith ott>.f ~~ ... t9COiI ••• ded 'Pf'-r ~ • ttIouId Ml ~ ....s wtth limit or ... y ~ tIO .-piM.! ...

The Implementation of an Accounting System for True Value in This Cost-Conscious Time, Using Handbook II. Second Revision.

ERIC Educational Resources Information Center

Moll, Emmett J.

The Milwaukee (Wisconsin) Public Schools (MPS) recently implemented a new, state-designed accounting system, called the Wisconsin Elementary and Secondary School Accounting System (WESSAS), based on guidelines proposed in the U.S. Office of Education's Handbook II. This report describes and discusses that implementation and provides numerous…

U.S. EPA, Pesticide Product Label, VOLCK SUPREME OIL SPRAY, 02/07/1983

EPA Pesticide Factsheets

2011-04-13

... I ;' o i i I .1' ~ •• ' I'r ~I!1r :: " "'lllil I \\ :: . II " I "t· . \\ II i I. j "I I: illll:h lHS P67810 " ' --, aw. I\\(X>'Fl~ ~~-t~l r.oJ 1:1',\\ I.",;, k t, ,-:! 3 7- j, () 3{ n:s ,;'-o!'~ ...

U.S. EPA, Pesticide Product Label, MR. HOLIDAY CALCIUM HYPOCHLORITE, 09/03/1985

EPA Pesticide Factsheets

2011-04-19

... QrdICfR- IIfT'r (')'rt.~>W!: ~i!"W- \\l'" It(I t,e 1lII\\IICI \\II., De hUI t1 s.~ ,), r, oec 11\\ flitS ~ ~tI ct ~ !"'- iIIl'31:J~ ~!Jet \\.'Id\\I lAd rI/JI:I. ~ ~~~ Ut .... " M:!.t ...

U.S. EPA, Pesticide Product Label, PARATHION 25 WETTABLE, 06/12/1989

EPA Pesticide Factsheets

2011-04-19

... II t\\llt.'U\\llIGLf IIIIlUDQu5. 011 "Ot b, •• I'" "POll •• U'" .. , t .,t '" "fl. "" ... t, d'uoul ., PI"'['' U •• , '"I., .nt. I.ut •• 11 .. ... 10ganberrie' and raspberries. ...

Analysis of Major Item Redistribution/Substitution Policies. Volume 2

DTIC Science & Technology

1980-05-01

juv11ld4vvb I 1 ki vat) 1 7A u,1 I / , Uju a I A,4/ FfA /1ILV)o 13bAvulu9db4 I 1 G vd 5utlA ’I b~𔃽 AAZ)I Ad-IUbC/H KC 5 jJuuu3337S 9 I I G~ v 2/ U)’ A...bblUut)1� 14 1 Do A I U(1b b150t) bbP ,(DV23g29bl 113 dj vb 4 It ’qvII lri U 4LJ I ebO 0b/5IUU~ddd5 I 1 d I~0d i’"Ikj O’.VI it/ II Ft-C;Ao beP 0e

Ergodic actions of SμU(2) on C∗-algebras from II1 subfactors

NASA Astrophysics Data System (ADS)

Pinzari, Claudia; Roberts, John E.

2010-03-01

To a proper inclusion N⊂M of II factors of finite Jones index [M:N], we associate an ergodic C∗-action of the quantum group SμU(2) (or more generally of certain groups Ao(F)). The higher relative commutant N'∩M can be identified with the spectral space of the rth tensor power u of the defining representation of the quantum group. The index and the deformation parameter are related by -1≤μ<0 and [M:N]=|μ+μ-1|. This ergodic action may be thought of as a virtual subgroup of SμU(2) in the sense of Mackey arising from the tensor category generated by the N-bimodule NMN. μ is negative as NMN is a real bimodule.

Transcription boundaries of U1 small nuclear RNA.

PubMed Central

Kunkel, G R; Pederson, T

1985-01-01

Transcription-proximal stages of U1 small nuclear RNA biosynthesis were studied by 32P labeling of nascent chains in isolated HeLa cell nuclei. Labeled RNA was hybridized to nitrocellulose-immobilized, single-stranded M13 DNA clones corresponding to regions within or flanking a human U1 RNA gene. Transcription of U1 RNA was inhibited by greater than 95% by alpha-amanitin at 1 microgram/ml, consistent with previous evidence that it is synthesized by RNA polymerase II. No hybridization to DNA immediately adjacent to the 5' end of mature U1 RNA (-6 to -105 nucleotides) was detected, indicating that, like all studied polymerase II initiation, transcription of U1 RNA starts at or very near the cap site. However, in contrast to previously described transcription units for mRNA, in which equimolar transcription occurs for hundreds or thousands of nucleotides beyond the mature 3' end of the mRNA, labeled U1 RNA hybridization dropped off sharply within a very short region (approximately 60 nucleotides) immediately downstream from the 3' end of mature U1 RNA. Also in contrast to pre-mRNA, which is assembled into ribonucleoprotein (RNP) particles while still nascent RNA chains, the U1 RNA transcribed in isolated nuclei did not form RNP complexes by the criterion of reaction with a monoclonal antibody for the small nuclear RNP Sm proteins. This suggests that, unlike pre-mRNA-RNP particle formation, U1 small nuclear RNP assembly does not occur until after the completion of transcription. These results show that, despite their common synthesis by RNA polymerase II, mRNA and U1 small nuclear RNA differ markedly both in their extents of 3' processing and their temporal patterns of RNP assembly. Images PMID:2942763

Distinguishing between HII regions and planetary nebulae with Hi-GAL, WISE, MIPSGAL, and GLIMPSE

NASA Astrophysics Data System (ADS)

Anderson, L. D.; Zavagno, A.; Barlow, M. J.; García-Lario, P.; Noriega-Crespo, A.

2012-01-01

Context. H II regions and planetary nebulae (PNe) both emit at radio and infrared (IR) wavelengths, and angularly small H II regions can be mistaken for PNe. This problem of classification is most severe for H II regions in an early evolutionary stage, those that are extremely distant, or those that are both young and distant. Previous work has shown that H II regions and PNe can be separated based on their infrared colors. Aims: Using data from the Herschel Hi-GAL survey, as well as WISE and the Spitzer MIPSGAL and GLIMPSE surveys, we wish to establish characteristic IR colors that can be used to distinguish between H II regions and PNe. Methods: We perform aperture photometry measurements for a sample of 126 H II regions and 43 PNe at wavelengths from 8.0 μm to 500 μm. Results: We find that H II regions and PNe have distinct IR colors. The most robust discriminating color criteria are [F12/F8] < 0.3, [F160/F12] > 1.3, and [F160/F24] > 0.8 (or alternately [F160/F22] > 0.8), where the brackets indicate the log of the flux ratio. All three of these criteria are individually satisfied by over 98% of our sample of H II regions and by ~10% of our sample of PNe. Combinations of these colors are more robust in separating the two populations; for example all H II regions and no PNe satisfy [F12/F8] < 0.4 and [F160/F22] > 0.8. When applied to objects of unknown classification, these criteria prove useful in separating the two populations. The dispersion in color is relatively small for H II regions; this suggests that any evolution in these colors with time for H II regions must be relatively modest. The spectral energy distributions (SEDs) of H II regions can be separated into "warm" and "cold" components. The "cold" component is well-fit by a grey-body of temperature 25 K. The SEDs of nearly two-thirds of our sample of H II regions peak at 160 μm and one third peak at 70 μm. For PNe, 67% of the SEDs peak at 70 μm, 23% peak at either 22 μm or 24 μm, and 9% (two sources) peak at 160 μm. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Tables 1 and 2 are available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/537/A1

Alpha List of Prime Contract Awards. Oct 91 - Sep 92. FY 92. (Mill Distributors Inc - North Bay Contracting)

DTIC Science & Technology

1993-01-01

4 m Cl) (1) a-4-4 (D C4 el im E~-ZN 0 0 -4 m IM mnif-4p0 to 410 0)N" 3 WWLIJ.1- a 0 0 0 0C00, 0C00. 0N 0-4-4 a > 2 Z -II 0-4o a ILI in1 a 000i N 2 2...4440 4I- 4(0 aN 4(0 LL 4(Z0IU A w N 04 I (0ON 442 ac 44~II4--. de wZZ~ ~ w2 . w( w0 w: CA: - Ř- 4. ( 00-4 9 4 w i w t 4 4-41(00 a-4 _j4 4 i-i - j j...0 0 0 0L U Imo 000 Ul NNNN N N V -IN NN N NN N N1 N W I WO0N U 0 0 U) a 1 0040N N 0 j0 de It 00 I ID 01- < 0 -C 0 4c ម coo lia 32 I.- I-. - a. I

Metal production in M 33: space and time variations

NASA Astrophysics Data System (ADS)

Magrini, L.; Stanghellini, L.; Corbelli, E.; Galli, D.; Villaver, E.

2010-03-01

Context. Nearby galaxies are ideal places to study metallicity gradients in detail and their time evolution. Aims: We analyse the spatial distribution of metals in M 33 using a new sample and the literature data on H ii regions, and constrain a model of galactic chemical evolution with H ii region and planetary nebula (PN) abundances. Methods: We consider chemical abundances of a new sample of H ii regions complemented with previous data sets. We compared H ii region and PN abundances obtained with a common set of observations taken at MMT. With an updated theoretical model, we followed the time evolution of the baryonic components and chemical abundances in the disk of M 33, assuming that the galaxy is accreting gas from an external reservoir. Results: From the sample of H ii regions, we find that i) the 2D metallicity distribution has an off-centre peak located in the southern arm; ii) the oxygen abundance gradients in the northern and southern sectors, as well as in the nearest and farthest sides, are identical within the uncertainties, with slopes around -0.03-4 dex kpc-1; iii) bright giant H ii regions have a steeper abundance gradient than the other H ii regions; iv) H ii regions and PNe have O/H gradients very close within the errors; v) our updated evolutionary model is able to reproduce the new observational constraints, as well as the metallicity gradient and its evolution. Conclusions: Supported by a uniform sample of nebular spectroscopic observations, we conclude that i) the metallicity distribution in M 33 is very complex, showing a central depression in metallicity probably due to observational bias; ii) the metallicity gradient in the disk of M 33 has a slope of -0.037 ± 0.009 dex kpc-1 in the whole radial range up to ~8 kpc, and -0.044 ± 0.009 dex kpc-1 excluding the central kpc; iii) there is little evolution in the slope with time from the epoch of PN progenitor formation to the present. Full Tables 2 and 3 are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/512/A63

SALT long-slit spectroscopy of quasar HE 0435-4312: fast displacement of the Mg II emission line

NASA Astrophysics Data System (ADS)

Średzińska, J.; Czerny, B.; Hryniewicz, K.; Krupa, M.; Kurcz, A.; Marziani, P.; Adhikari, T. P.; Basak, R.; You, B.; Wang, J.-M.; Hu, C.; Pych, W.; Bilicki, M.

2017-05-01

Context. The Mg II emission line is visible in the optical band for intermediate redshift quasars (0.4 < z < 1.6) and it is thus an extremely important tool to measure the black hole mass and to understand the structure of the Broad line region (BLR). Aims: We aim to determine the substructure and the variability of the Mg II line with the aim to identify which part of the line comes from a medium in Keplerian motion. Methods: Using the Southern African Large Telescope (SALT) with the Robert Stobie Spectrograph (RSS) we performed ten spectroscopic observations of quasar HE 0435-4312 (z = 1.2231) over a period of three years (Dec. 23/24, 2012 to Dec. 7/8, 2015). Results: Both the Mg II line and the Fe II pseudo-continuum increase with time. We clearly detect the systematic shift of the Mg II line with respect to the Fe II over the years, corresponding to the acceleration of 104 ± 14 km s-1 yr-1 in the quasar rest frame. The Mg II line shape is clearly non-Gaussian but single-component, and the increase in line equivalent width and line shift is not accompanied with significant evolution of the line shape. We analyse the conditions in the Mg II and Fe II formation region and we note that the very large difference in the covering factor and the turbulent velocity also support the conclusion that the two regions are spatially separated. Conclusions: The measured acceleration of the line systematic shift is too large to connect it with the orbital motion at a distance of the BLR in this source. It may imply a precessing inner disk illuminating the BLR. Further monitoring is still needed to better constrain the variability mechanism. Based on observations made with the Southern African Large Telescope (SALT) under program 2012-2-POL-003 and 2013-1-POL-RSA-002 (PI: B. Czerny).Spectra shown in Figs. 3 and 4 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/601/A32

U.S. EPA, Pesticide Product Label, , 08/15/1983

EPA Pesticide Factsheets

2011-04-14

... '01 I. , I 1 ; 1:: ' " (I • • '1-' ') , i (. :., _ ~~ ::._ ., 1(;166 j ----. I -- B. 1'r,\\tt 11'., cl intuit :.r'l"co fh\\ckcn!J.1(!~", UJ O,/r,I,Jl htttu\\t inn I II. U. Pt.,u uontlU:ROOl ...

How Quickly Can Attention Affect Form Perception?

DTIC Science & Technology

1987-11-01

8217.O6/ N I ’P. * 1 . wlll25 iI u i A.i’ .:--. % % Ar Wl % -% W %* ----------- *, U" 1 % AFHRL-TR-87-28 INc IL FIECopy ON 1AIR FORCE 141 HOW QUICKLY CAN...After- a [ruit variible interval, four, 1 -likc target fiquris Wert, presented, one at each location, loll owedi by ti/asks. (hi ol server th/er idi...C cue is presented near the target, can also be. Oltai li/i Wi tih d~ p( rifrte at1Xiiti IFil, g1) 1 onS~ii t iifIt [LTaC tic(’ This argues that sucih

Device Comparison for Determining Field Soil Moisture Content

DTIC Science & Technology

2011-11-01

properties. Tests conducted on each soil included grain size distribution with hydrometer analysis for dissemination of silt and clay fractions, Atterberg...ER D C/G SL TR -11-42 43 Clay-G ravel (SP-SC) - --- U.S, SIEVE OPENING II’! INCHES US. STANDIIRD SIEVE NUMBERS HYDROMETER Rln 1...STANOAR!l S<Eiil: NUMBERS HYDROMETER 1~1n. ~ln. 3/8.., o\\ ’ll """ """ li14ll"""’ fH, . , .. ~in. • 100 I I I’ I I l I ~ _u I I II 0 I I ~’r- ’Ŕ

Laser-Based Fuel Cell Manufacturing for Thermal Management

DTIC Science & Technology

2005-10-12

r IMITA T O 6 1 i I1 .114 141-" n. 14 F . I #1 l i f II 0I0 1(P ,1 L P ER I II I U-ABSTRACT- ------- U inr I L nEron ; . A , wl "t . Tills rAI Ou 1 0...concentration is too low to form a connecting network of conductive sites. On the other hand, the material undergoes a sharp transition from...carbon black loading due to the development of a network of closely-seated CB particles. The predicted very high electrical resistivity for 1 and 2 Vol

Process for Transition of Uranium Mill Tailings Radiation Control Act Title II Disposal Sites to the U.S. Department of Energy Office of Legacy Management for Long-Term Surveillance and Maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This document presents guidance for implementing the process that the U.S. Department of Energy (DOE) Office of Legacy Management (LM) will use for assuming perpetual responsibility for a closed uranium mill tailings site. The transition process specifically addresses sites regulated under Title II of the Uranium Mill Tailings Radiation Control Act (UMTRCA) but is applicable in principle to the transition of sites under other regulatory structures, such as the Formerly Utilized Sites Remedial Action Program.

A Structural Weight Estimation Program (SWEEP) for Aircraft. Volume 6 - Wing and Empennage Module. Appendix C: Program Flow Charts, Overlays (9.0) and (10,0)

DTIC Science & Technology

1974-06-01

NQUI II.CH Uj^f^i.»! orwi MI-../f;*« MA orrrtAi IOHAI niuipi imiAi mioi tu U/IN IK «»At IB MIDI win» t np roKnAi im fx.ir...rj0lll.f<CC9>l,(DCUI.II??)l. ICKi«. TDOUIfi I, IK . >’. TlKWi Si I. l!Ü>X. lOKJrs I). ( WAV .rtXO»». ((;XW.»;)(*>.U.(KlMi)(ClH.MOP|.rt)(a’M, lWM3i

Far ultraviolet wide field imaging and photometry - Spartan-202 Mark II Far Ultraviolet Camera

NASA Technical Reports Server (NTRS)

Carruthers, George R.; Heckathorn, Harry M.; Opal, Chet B.; Witt, Adolf N.; Henize, Karl G.

1988-01-01

The U.S. Naval Research Laboratory' Mark II Far Ultraviolet Camera, which is expected to be a primary scientific instrument aboard the Spartan-202 Space Shuttle mission, is described. This camera is intended to obtain FUV wide-field imagery of stars and extended celestial objects, including diffuse nebulae and nearby galaxies. The observations will support the HST by providing FUV photometry of calibration objects. The Mark II camera is an electrographic Schmidt camera with an aperture of 15 cm, a focal length of 30.5 cm, and sensitivity in the 1230-1600 A wavelength range.

Feasibility Study for a Structurally Efficient, Multi-Modal Shelter Concept Utilizing Advanced Technology Production Techniques

DTIC Science & Technology

1974-02-01

II I~ x p:1 ns ion P roc cuurc Longitudin:-11 Section, Container Mod·c Configuration r Ex p :m s i on Pro c c d u r e Longitudinal Section...No . I II. I I I. IV. v. VI. VII. VIII. IX. X . XI. XII. XIII. XIV. XV . XVI. XVII . XVIII . XIX. XX. XXI. XXII . XXI II. XXIV...mat e rial s and examples from these categories . Glass Fibers Glass Mi c r os pheres As bestos Carbon Graphite Ce llulose Cotton Jute Rayo n

Dollar Summary of Prime Contract Awards by Contractor, State or Country, and Place. Part 3 (E&E Reisen - Hiawatha Rubber Co)

DTIC Science & Technology

1990-01-01

w ui 3j W3A b a w ww w w u i U j L A u a w Wa 4*to a o a N C4 anL (a "Cc cm em an a aD a A a GOO F6 46 404 S. >0 I.J man com 04 R 12 CM e4cc ~ m I...I WC: I co r aCCa 001 I-I 0. 0 NCJ o #1.U0 1-- 44 4 -4W C )C (JN -4~y 001 4 4 1I~ C’I1- mmcoco 44 I I. 4 C . a I- U. >- -4.- 010 00 - 1 . Za -C 4 vm...6W1-6z x. z-z- U~.L 4c -C I.--.4- z~L L W~mm 09~ ac -4- U..CI -I io ACLZ 0 U 3 0 0 (0 62 0 z I. zzz (A 6 000 Csd 314" 6 6 CA (ft 4.WU U . U A F4 F6 I I

Geochemistry of the alginite and amorphous organic matter from type II-S kerogens

USGS Publications Warehouse

Stankiewicz, B.A.; Kruge, M.A.; Mastalerz, Maria; Salmon, G.L.

1996-01-01

Maceral fractions of the Type II-S kerogens from the Monterey Formation (Miocene. California. U.S.A.) and Duwi Formation (Campanian/Maastrichtian, Egypt) were separated by density gradient centrifugation. The Monterey Fm. kerogen sample was comprised chiefly of light red-fluorescing amorphous organic matter (AOM), the flash pyrolyzate of which was characterized by a predominance of alkylbenzenes, alkylthiophenes and alkylpyrroles. In contrast, the pyrolyzates of its alginite concentrate showed a highly aliphatic character, typical of this maceral, with the series of n-alkenes and n-alkanes (C6- C26) predominating. The pyrolyzate of the dominant light brown-fluorescing AOM of the Duwi Fm. kerogen had a relatively high concentration of alkylbenzenes and alkylthiophenes, while its elginite concentrate showed a more aliphatic character upon pyrolysis. There was a marked enrichment of thiophenic sulfur in the light-colored AOM of both samples (and also pyrrolic nitrogen in the case of the Monterey) relative to the alginite. The results support a bacterially-mediated, degradative origin for Type II-S amorphous organic matter, with algal remains as the primary source of the kerogen.

77 FR 22480 - Conduit Financing Arrangements; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-16

... as follows: Authority: 26 U.S.C. 7805 * * * Sec. 1.881-3 [Amended] 0 Par. 2. For each entry in the..., 2, 3 Examples 1, 2, 3 and 4. (a)(2)(i)(A). Last sentence of paragraph Examples 4 and 5 Examples 5 and 6. (a)(2)(i)(B). Last sentence of paragraph Example 6 Example 7. (a)(3)(ii)(E)(2)(ii). Last...

A Prediction for the Outcome of Press-Enterprise Co. v. Superior Court (II).

ERIC Educational Resources Information Center

Schwartz, Thomas A.

To determine whether U.S. Supreme Court judges have a systematic attitude toward court cases dealing with the law of newsgathering and fair trial-free press, and whether that attitude can help predict the outcome of the pending case Press-Enterprise Co. v. Superior Court (II), this paper applies an attitudinal theory from the field of social…

Remedial Investigation/Feasibility Study Fort Dix U.S. Army Installation Fort Dix, New Jersey

DTIC Science & Technology

1994-01-01

METHOD: PARTICULATE FILTER; GRAVIMETRIC: (NIOSH VOL. Ill I 8583 , NUISANCE DUST (TOTAL)). »OSHA REVOKED THE FINAL RULE LIMITS OF JANUARY 19, 1989 IN...VJ ISO .- i-.i^ !...= : \\J~::— :!__’ii!-!lS . l~>.-- -.^ - ORAL-MCUSE LD50i 5SS0 MO/KG ORAL-rAf-iivifcii i LD50: 750 MG

U.S. EPA, Pesticide Product Label, TIME-SAVER LIQUID BACTERICIDE, 02/04/2003

EPA Pesticide Factsheets

2011-04-14

... "~1:I']i,!~: 3- Itt-iii I[ e turE lfhl tu if; ltllf~ H! Lf= i! ~ l,l[~ r or i ;:li{f" lt~~' t 1[" f ~ll~ f pl [1: tl ir~ l tIll i l t .!r~ ti~fr {~llhg Uf ttHjf } itt!t f t~ t ~, ' -; irlt, if-II 0 ...

29 CFR 782.1 - Statutory provisions considered.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 1935, (part II of the Interstate Commerce Act, 49 Stat. 546, as amended; 49 U.S.C. 304, as amended by Pub. L. 89-670, section 8e which substituted “Secretary of Transportation” for “Interstate Commerce... solely by virtue of section 204(a)(3a) of part II of the Interstate Commerce Act. (Pub. L. 939, 84th Cong...

78 FR 33871 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

... Items I, II and III below, which items have been prepared by the self-regulatory organization. The.... \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the...). II. Self-Regulatory Organization's Statement of the Purpose of, and Statutory Basis for, the Proposed...

78 FR 33880 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

... Items I, II and III below, which items have been prepared by the self-regulatory organization. The.... \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the...). II. Self-Regulatory Organization's Statement of the Purpose of, and Statutory Basis for, the Proposed...

Emerging Technologies Program Integration Report. Volume 2. Background, Delphi and Workshop Data. Appendices

DTIC Science & Technology

1987-05-04

FTIILE COP’ AD-A196 840 EMERGING TECHNOLOGIES PROGRAM INTEGRATION REPORT VOLUME II BACKGROUND, DELPHI AND WORKSHOP DATA, APPENDICES . -- PREPARED...Security Classification) Emerging Technologies Program Integration Report Volume II: Background, Delphi and Workshop Data; Appendices (U) 12 PERSONAL...volumes of this integration report assess and synthesize information gathered through a Delphi survey, defense needs prioritization workshops, and

Summary - National Dissemination and the Five Target States, Part 3, Final Report for Phase II--Dissemination, Rural Shared Services.

ERIC Educational Resources Information Center

Northern Montana Coll., Havre.

The dissemination phase (Phase II) of the Rural Shared Services Project is reported in this document. Efforts of the dissemination phase were concentrated in 5 target states: Vermont, Georgia, Wyoming, Montana, and New Mexico; national dissemination was limited to attendance at national conferences, the U. S. Office of Education PREP materials for…

77 FR 43861 - Importer of Controlled Substances; Notice of Application; Akorn, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

...), a basic class of controlled substance listed in schedule II. The company plans to import Remifentanil in bulk for use in dosage- form manufacturing. Any bulk manufacturer who is presently, or is... schedules I or II, which fall under the authority of section 1002(a)(2)(B) of the Act [21 U.S.C. 952(a)(2)(B...

In Vitro Screening of 1877 Industrial and Consumer Chemicals, Pesticides and Pharmaceuticals in up to 782 Assays: ToxCast Phase I and II (SOT)

EPA Science Inventory

In Phase II of the ToxCast program, the U.S. EPA and Tox21 partners screened 1,877 chemicals, including pesticides; food, cosmetics and personal care ingredients; pharmaceuticals; and industrial chemicals. Testing used a 782 in vitro assays across 7 technologies and multiple bi...

21 CFR 1305.04 - Persons entitled to order Schedule I and II controlled substances.

Code of Federal Regulations, 2011 CFR

2011-04-01

... to order Schedule I and II controlled substances. (a) Only persons who are registered with DEA under... are registered with DEA under section 1008 of the Act (21 U.S.C. 958) to export these substances may obtain and use DEA Form 222 (order forms) or issue electronic orders for these substances. Persons not...

21 CFR 1305.04 - Persons entitled to order Schedule I and II controlled substances.

Code of Federal Regulations, 2010 CFR

2010-04-01

... to order Schedule I and II controlled substances. (a) Only persons who are registered with DEA under... are registered with DEA under section 1008 of the Act (21 U.S.C. 958) to export these substances may obtain and use DEA Form 222 (order forms) or issue electronic orders for these substances. Persons not...

America in World War II: An Analysis of History Textbooks from England, Japan, Sweden, and the United States

ERIC Educational Resources Information Center

Foster, Stuart; Nicholls, Jason

2005-01-01

This study examined how textbooks from England, Japan, Sweden, and the United States portray America's role in World War II. Analysis of the central story lines revealed that historical information purveyed to students in different nations varies considerably. Accordingly, U.S. textbooks emphasize the significant and pre-eminent role that the…

World War II Unit. Using Primary Sources in the Classroom.

ERIC Educational Resources Information Center

Alabama Dept. of Archives and History, Montgomery.

This teaching unit, "World War II Unit," is the ninth in a series of 10 units about Alabama state history, part of a project designed to help teachers integrate the use of primary source materials into their classrooms. Although the units are designed to augment the study of Alabama, they are useful in the study of U.S. history, world…

HEALTH EFFECTS OF CHRONIC EXPOSURE TO ARSENIC VIA DRINKING WATER IN INNER MONGOLIA: II. VIBROTACTILE AND VISUAL MEASURES FINAL DOCUMENT TITLE.

EPA Science Inventory

HEALTH EFFECTS OF CHRONIC EXPOSURE TO ARSENIC IN DRINKING WATER IN INNER MONGOLIA: II. VIBROTACTILE AND VISUAL MEASURES.

David Otto, Ph.D., Judy Mumford, Ph.D., Richard Kwok, M.S.P.H., Ken Hudnell, Ph.D.,
U.S. Environmental Protection Agency; Yanhong Li, M.D., Yajuan ...

U.S. EPA, Pesticide Product Label, , 11/05/1985

EPA Pesticide Factsheets

2011-04-21

... Ap,l, ., p,.-~I... •• 1 ~I ••• "ra". Us. 0.75 I. I p •••• , r 100 ,.II •• s •• ,.ndiA, 00 dis •• s. ,.v.rily. ",y •• IS.. it lOountnh sp,.ys .t •• uiulnl nhs. fll' it,"1 .ppli,.tion II. ...

A Mini-BAL Outflow at 900 pc from the Central Source: VLT/X-shooter Observations

NASA Astrophysics Data System (ADS)

Xu, Xinfeng; Arav, Nahum; Miller, Timothy; Benn, Chris

2018-05-01

We determine the physical conditions and location of the outflow material seen in the mini-BAL quasar SDSS J1111+1437 (z = 2.138). These results are based on the analysis of a high S/N, medium-resolution VLT/X-shooter spectrum. The main outflow component spans the velocity range ‑1500 to ‑3000 km s‑1 and has detected absorption troughs from both high-ionization species: C IV, N V, O VI, Si IV, P V, and S IV; and low-ionization species: H I, C II, Mg II, Al II, Al III, Si II, and Si III. Measurements of these troughs allow us to derive an accurate photoionization solution for this absorption component: a hydrogen column density, {log}({N}{{H}})={21.47}-0.27+0.21 cm‑2 and ionization parameter, {log}({U}{{H}})=-{1.23}-0.25+0.20. Troughs produced from the ground and excited states of S IV combined with the derived {U}{{H}} value allow us to determine an electron number density of {log}({n}{{e}})={3.62}-0.11+0.09 cm‑3 and to obtain the distance of the ionized gas from the central source: R={880}-260+210 pc.

NASA Remembers Astronaut Bruce McCandless II

NASA Image and Video Library

2017-12-22

Former NASA Astronaut Bruce McCandless II, best known for his iconic free-floating spacewalk on a 1984 shuttle flight, died on Dec. 21 at the age of 80. A native of Boston, McCandless II attended the U.S. Naval Academy and served as a naval aviator before joining NASA in 1966. He served in support or backup roles during the Apollo and Skylab programs, including serving as the communicator from mission control to the Apollo 11 crew during their historic 1969 moonwalk. On Feb. 7, 1984, during the Space Shuttle Challenger’s STS-41B mission, he made the first, untethered, free flight spacewalk in the Manned Maneuvering Unit. In 1990, McCandless II was part of the crew on Space Shuttle Discovery’s STS-31 mission, which deployed the Hubble Space Telescope.

Emergency Destruction of Information Storing Media. Appendix 2. Destruct Technology Compendium

DTIC Science & Technology

1987-12-01

L C U) 00 r. C 0 Z EC 0 00 CD CD 00 C4 C ) .0 -F 0 j o ) .0...0 cmc ,go~ S.- .) cm X.3 .1 . 1 1 1 1 1V ,a Ic 00 ON .t CM CI CmcyI CI W! W! U c t!.- CCJ .C-c v4 N OD V t 40 -z -- a- -~ LL A to) N ot SQ0 U. L CL...Y LL CL No LA ILP- LDl a .49 zII ii a A C.0 Am to- • ! t -.- t - - - - lin -sea hi ~ ~~~ CM .-. 2 2 Ll L . C C4 00 L h a so 0~ UP ,nDa gus 0. 1~2’ - - L

7 CFR 1486.209 - How are program applications evaluated and approved?

Code of Federal Regulations, 2010 CFR

2010-01-01

... maintain U.S. market share; (ii) Marketing and distribution of value-added products, including new products... channels in emerging markets, including infrastructural impediments to U.S. exports; such studies may...

U.S. Regional Deterrence Strategies

DTIC Science & Technology

1995-01-01

MOTIVATIONS OF REGIONAL ADVERSARIES ............................. 27 Regime Types ................................. 27 Domestic Political Instability...32 Historical Cases Illustrating the influence of Domestic Politics .................................. 36 China, 1950... Political Constraints ............................. 86 Military Constraints ............. II................89 Deterrence in U.S. Regional Strategy

Type II diabetes mellitus and the incidence of epithelial ovarian cancer in the cancer prevention study-II nutrition cohort.

PubMed

Gapstur, Susan M; Patel, Alpa V; Diver, W Ryan; Hildebrand, Janet S; Gaudet, Mia M; Jacobs, Eric J; Campbell, Peter T

2012-11-01

Despite consistent associations of type II diabetes mellitus with hormonally related cancers such as breast and endometrium, the relation between type II diabetes mellitus and ovarian cancer risk is unclear. Associations of type II diabetes mellitus status, duration, and insulin use with epithelial ovarian cancer overall, and with serous and nonserous histologic subtypes were examined in the Cancer Prevention Study-II Nutrition Cohort, a prospective study of U.S. men and women predominantly aged 50 years and older. Between 1992 and 2007, 524 incident epithelial ovarian cancer cases were identified among 63,440 postmenopausal women. Multivariable-adjusted relative risks (RR) and 95% confidence intervals (CI) were computed using extended Cox regression to update diabetes status and bilateral oophorectomy status during follow-up. Type II diabetes mellitus status (RR = 1.05; 95% CI, 0.75-1.46) and duration were not associated with epithelial ovarian cancer risk. Although not statistically significantly different (P(difference) = 0.39), the RR was higher for type II diabetes mellitus with insulin use (RR = 1.28; 95% CI, 0.74-2.24) than for type II diabetes mellitus without insulin use (RR = 0.96; 95% CI, 0.64-1.43). Diabetes seemed to be more strongly associated with nonserous (RR = 1.41; 95% CI, 0.70-2.85) than serous (RR = 0.71; 95% CI, 0.41-1.23) histologic subtypes. Type II diabetes mellitus was not associated with risk of epithelial ovarian cancer, although higher risks with nonserous subtypes and among insulin users cannot be ruled out. Larger studies are needed to clarify associations of type II diabetes mellitus with or without insulin use with risk of ovarian cancer overall and by histologic subtypes. ©2012 AACR.

7 CFR 51.685 - U.S. Combination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Combination. 51.685 Section 51.685 Agriculture....685 U.S. Combination. “U.S. Combination” consists of a combination of U.S. No. 1 and U.S. No. 2 oranges: Provided, That the number of U.S. No. 2 fruits specified in § 51.689, Tables I and II, are not...

Great River Environmental Action Team II. (GREAT II). Upper Mississippi River (Guttenberg, Iowa to Saverton, Missouri). Recreation Work Group. Appendix.

DTIC Science & Technology

1980-12-01

4 1-40 0*r - 04 mr. A-4 A.) 0 00 co 0) r. 4-40 W 1 𔃺Q)0 cc 0 0 .0 0 u 0 U .0 0 0 0 04 0HD 01. 40 A0 1H U) . td p- wu 0c W~ to 0 0.E $U -i 0.4 0w 0...w0 4 0 4) 44 44 0) -4 C: w w . Or,-% 4) ..4 0 ri4 4 w 0 04 1 0-4 " -4 go Q4 v0 0000P 51~N S. C 40 J 0 0 0n v 0 v 0 C -4 )k4 WW0-4 4),- 4bd oo. 4J1 (fl 0

Processes affecting transport of uranium in a suboxic aquifer

USGS Publications Warehouse

Davis, J.A.; Curtis, G.P.; Wilkins, M.J.; Kohler, M.; Fox, P.; Naftz, D.L.; Lloyd, J.R.

2006-01-01

At the Naturita site in Colorado, USA, groundwaters were sampled and analyzed for chemical composition and by culture and culture-independent microbiological techniques. In addition, sediments were extracted with a dilute sodium carbonate solution to determine quantities of labile uranium within the sediments. Samples from the upgradient portion of the contaminated aquifer, where very little dissolved Fe(II) is found in the groundwater, have uranium content that is controlled by U(VI) adsorption and few metal-reducing bacteria are observed. In the extreme downgradient portion of the aquifer, where dissolved Fe(II) is observed, uranium content of the sediments includes significant quantities of reduced U(IV) and diverse populations of Fe(III)-reducing bacteria were present in the subsurface with the potential of reducing U(VI) to U(IV). ?? 2006 Elsevier Ltd. All rights reserved.

Prime Contract Awards Alphabetically by Contractor, State or Country, and Place. Part 12 (McFadden Jimmy, Portugal - NCR Japan LTD, Japan), FY1991

DTIC Science & Technology

1991-01-01

a .- 3 30 3030 300 3cm 3.4 30 3-00< 3 0. ataa0.4 II ow 4(:0( c0 4 40 100 4N4 40 a 0 40)0 4o-M00 doU 0.4 Nc o WO g aW0 cca Q0 .) adO U0 0 o c - (L...Go05o- 0 0 -4 1- ,000 I.U0 co 000 U cc- 100 U a. U L I ON U -4 .4 -.4 L.4..4 -4 .. 444- -~..4- 444 m4 o ’W’ I :00 4 cc00 -1.4I 000C )> .4 00 000000000...1900 0 1LLLS.*.O IUIiL.UjO 0 0 0 0 we *_ c. U i z0~ EiLS-nj ..JJi 1I I -3Ii 1 I I1 0 ME iC1-4 W U0 WMCI-4 NO 0 0 a Ia N 1 00-4 N 7-00 ado 5* 100 W0O

Functionalization of Magnetic Chitosan Particles for the Sorption of U(VI), Cu(II) and Zn(II)—Hydrazide Derivative of Glycine-Grafted Chitosan

PubMed Central

Hamza, Mohammed F.; Aly, Mohsen M.; Abdel-Rahman, Adel A.-H.; Ramadan, Samar; Raslan, Heba; Wang, Shengye; Vincent, Thierry; Guibal, Eric

2017-01-01

A new magnetic functionalized derivative of chitosan is synthesized and characterized for the sorption of metal ions (environmental applications and metal valorization). The chemical modification of the glycine derivative of chitosan consists of: activation of the magnetic support with epichlorohydrin, followed by reaction with either glycine to produce the reference material (i.e., Gly sorbent) or glycine ester hydrochloride, followed by hydrazinolysis to synthesize the hydrazide functionalized sorbent (i.e., HGly sorbent). The materials are characterized by titration, elemental analysis, FTIR analysis (Fourrier-transform infrared spectrometry), TGA analysis (thermogravimetric analysis) and with SEM-EDX (scanning electron microscopy coupled to energy dispersive X-ray analysis). The sorption performances for U(VI), Cu(II), and Zn(II) are tested in batch systems. The sorption performances are compared for Gly and HGly taking into account the effect of pH, the uptake kinetics (fitted by the pseudo-second order rate equation), and the sorption isotherms (described by the Langmuir and the Sips equations). The sorption capacities of the modified sorbent reach up to 1.14 mmol U g−1, 1.69 mmol Cu g−1, and 0.85 mmol Zn g−1. In multi-metal solutions of equimolar concentration, the chemical modification changes the preferences for given metal ions. Metal ions are desorbed using 0.2 M HCl solutions and the sorbents are re-used for five cycles of sorption/desorption without significant loss in performances. PMID:28772896

Spectroscopic and functional characterization of iron-bound forms of Azotobacter vinelandii (Nif)IscA.

PubMed

Mapolelo, Daphne T; Zhang, Bo; Naik, Sunil G; Huynh, Boi Hanh; Johnson, Michael K

2012-10-16

The ability of Azotobacter vinelandii(Nif)IscA to bind Fe has been investigated to assess the role of Fe-bound forms in NIF-specific Fe-S cluster biogenesis. (Nif)IscA is shown to bind one Fe(III) or one Fe(II) per homodimer and the spectroscopic and redox properties of both the Fe(III)- and Fe(II)-bound forms have been characterized using the UV-visible absorption, circular dichroism, and variable-temperature magnetic circular dichroism, electron paramagnetic resonance, Mössbauer and resonance Raman spectroscopies. The results reveal a rhombic intermediate-spin (S = 3/2) Fe(III) center (E/D = 0.33, D = 3.5 ± 1.5 cm(-1)) that is most likely 5-coordinate with two or three cysteinate ligands and a rhombic high spin (S = 2) Fe(II) center (E/D = 0.28, D = 7.6 cm(-1)) with properties similar to reduced rubredoxins or rubredoxin variants with three cysteinate and one or two oxygenic ligands. Iron-bound (Nif)IscA undergoes reversible redox cycling between the Fe(III)/Fe(II) forms with a midpoint potential of +36 ± 15 mV at pH 7.8 (versus NHE). l-Cysteine is effective in mediating release of free Fe(II) from both the Fe(II)- and Fe(III)-bound forms of (Nif)IscA. Fe(III)-bound (Nif)IscA was also shown to be a competent iron source for in vitro NifS-mediated [2Fe-2S] cluster assembly on the N-terminal domain of NifU, but the reaction occurs via cysteine-mediated release of free Fe(II) rather than direct iron transfer. The proposed roles of A-type proteins in storing Fe under aerobic growth conditions and serving as iron donors for cluster assembly on U-type scaffold proteins or maturation of biological [4Fe-4S] centers are discussed in light of these results.

Gold nanoparticle-based simple colorimetric and ultrasensitive dynamic light scattering assay for the selective detection of Pb(II) from paints, plastics, and water samples.

PubMed

Beqa, Lule; Singh, Anant Kumar; Khan, Sadia Afrin; Senapati, Dulal; Arumugam, Sri Ranjini; Ray, Paresh Chandra

2011-03-01

Pb (II) is a common water pollutant with high toxicity. According to the CDC, about 310,000 U.S. children of ages 1-5 have high levels of lead in their blood that it is due to the exposure to lead from plastic toys and other products. As a result, the development of ultrasensitive assays for the real-time detection of Pb(II) from plastic toys and paints is very important for water controlling, clinical toxicology and industrial processes. Driven by the need to detect trace amounts of Pb(II) from water samples, we report a label-free, highly selective and ultra sensitive glutathione modified gold nanoparticle based dynamic light scattering (DLS) probe for Pb(II) recognition in 100 ppt level from aqueous solution with excellent discrimination against other heavy metals. The sensitivity of our assay to detect Pb(II) level in water is almost 2 orders of magnitude higher than the EPA standard limit. We have also demonstrated that our DLS assay is capable of measuring the amount of Pb(II) in paint, plastic toys, and water from MS river. A possible mechanism and operating principles of our DLS assay have been discussed. Ultimately, this nanotechnology driven assay could have enormous potential applications in rapid, on-site monitoring of Pb(II) from day-to-day sample.

Hyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins

PubMed Central

Lakraj, Amanda-Amrita D.; Moghimi, Narges; Jabbari, Bahman

2013-01-01

Clinical features, anatomy and physiology of hyperhidrosis are presented with a review of the world literature on treatment. Level of drug efficacy is defined according to the guidelines of the American Academy of Neurology. Topical agents (glycopyrrolate and methylsulfate) are evidence level B (probably effective). Oral agents (oxybutynin and methantheline bromide) are also level B. In a total of 831 patients, 1 class I and 2 class II blinded studies showed level B efficacy of OnabotulinumtoxinA (A/Ona), while 1 class I and 1 class II study also demonstrated level B efficacy of AbobotulinumtoxinA (A/Abo) in axillary hyperhidrosis (AH), collectively depicting Level A evidence (established) for botulinumtoxinA (BoNT-A). In a comparator study, A/Ona and A/Inco toxins demonstrated comparable efficacy in AH. For IncobotulinumtoxinA (A/Inco) no placebo controlled studies exist; thus, efficacy is Level C (possibly effective) based solely on the aforementioned class II comparator study. For RimabotulinumtoxinB (B/Rima), one class III study has suggested Level U efficacy (insufficient data). In palmar hyperhidrosis (PH), there are 3 class II studies for A/Ona and 2 for A/Abo (individually and collectively level B for BoNT-A) and no blinded study for A/Inco (level U). For B/Rima the level of evidence is C (possibly effective) based on 1 class II study. Botulinum toxins (BoNT) provide a long lasting effect of 3–9 months after one injection session. Studies on BoNT-A iontophoresis are emerging (2 class II studies; level B); however, data on duration and frequency of application is inconsistent. PMID:23612753

HLA antibodies and soluble CD30 are associated with poor renal graft outcome: updated results of a single-center cross-sectional study.

PubMed

Langan, Leanne L; D'Orsogna, Lloyd; Park, Lawrence P; Hughes, Tiffany L; Irish, Ashley; Luxton, Grant; Witt, Campbell S; Christiansen, Frank T

2006-01-01

In a previous study, we have shown that HLA class II antibodies and a high soluble CD30 (sCD30) measured at least 1 year post-transplant predict subsequent graft failure. We have now updated the results of this same cohort of 208 patients 15 months later. HLA-specific antibodies (class I and class II) were detected by ELISA LAT-M and Luminex LabScreen assays. Data on graft outcome was collected with a median follow-up of 4.7 years. By Kaplan-Meier analysis, class II antibody was again associated with a poorer outcome, with an estimated 6-year graft survival of 67% and 71% when detected by ELISA and Luminex, respectively, compared with 92% for those without class II antibody (p < or = 0.0001). A soluble CD30 level of > or = 100 U/ml was also associated with a poorer estimated 6-year graft survival (p = 0.02). HLA antibodies and high sCD30 (> or = 100 U/ml) had an additive effect such that those with both high sCD30 and class II antibodies had a hazard ratio for subsequent graft failure of 18.1 (p = 0.0008) and 8.6 (p = 0.007) when detected by ELISA and Luminex, respectively. These data show that detection of HLA class II antibodies and serum sCD30 measured at least 1 year post-transplant continues to predict a subsequent outcome up to 6 years after the initial measurement; they also show that such measures provide important information that may allow for modification of ongoing therapy.

Microbially catalyzed nitrate-dependent metal/radionuclide oxidation in shallow subsurface sediments

NASA Astrophysics Data System (ADS)

Weber, K.; Healy, O.; Spanbauer, T. L.; Snow, D. D.

2011-12-01

Anaerobic, microbially catalyzed nitrate-dependent metal/radionuclide oxidation has been demonstrated in a variety of sediments, soils, and groundwater. To date, studies evaluating U bio-oxidation and mobilization have primarily focused on anthropogenically U contaminated sites. In the Platte River Basin U originating from weathering of uranium-rich igneous rocks in the Rocky Mountains was deposited in shallow alluvial sediments as insoluble reduced uranium minerals. These reduced U minerals are subject to reoxidation by available oxidants, such nitrate, in situ. Soluble uranium (U) from natural sources is a recognized contaminant in public water supplies throughout the state of Nebraska and Colorado. Here we evaluate the potential of anaerobic, nitrate-dependent microbially catalyzed metal/radionuclide oxidation in subsurface sediments near Alda, NE. Subsurface sediments and groundwater (20-64ft.) were collected from a shallow aquifer containing nitrate (from fertilizer) and natural iron and uranium. The reduction potential revealed a reduced environment and was confirmed by the presence of Fe(II) and U(IV) in sediments. Although sediments were reduced, nitrate persisted in the groundwater. Nitrate concentrations decreased, 38 mg/L to 30 mg/L, with increasing concentrations of Fe(II) and U(IV). Dissolved U, primarily as U(VI), increased with depth, 30.3 μg/L to 302 μg/L. Analysis of sequentially extracted U(VI) and U(IV) revealed that virtually all U in sediments existed as U(IV). The presence of U(IV) is consistent with reduced Fe (Fe(II)) and low reduction potential. The increase in aqueous U concentrations with depth suggests active U cycling may occur at this site. Tetravalent U (U(IV)) phases are stable in reduced environments, however the input of an oxidant such as oxygen or nitrate into these systems would result in oxidation. Thus co-occurrence of nitrate suggests that nitrate could be used by bacteria as a U(IV) oxidant. Most probable number enumeration of nitrate-dependent U(IV) oxidizing microorganisms demonstrated an abundant community ranging from 1.61x104 to 2.74x104 cells g-1 sediment. Enrichments initiated verified microbial U reduction and U oxidation coupled to nitrate reduction. Sediment slurries were serially diluted and incubated over a period of eight weeks and compared to uninoculated controls. Oxidation (0-4,554 μg/L) and reduction (0-55 μg/L) of U exceeded uninoculated controls further providing evidence of a U biogeochemical cycling in these subsurface sediments. The oxidation of U(IV) could contribute to U mobilization in the groundwater and result in decreased water quality. Not only could nitrate serve as an oxidant, but Fe(III) could also contribute to U mobilization. Nitrate-dependent Fe(II) oxidation is an environmentally ubiquitous process facilitated by a diversity of microorganisms. Additional research is necessary in order to establish a role of biogenic Fe(III) oxides in U geochemical cycling at this site. These microbially mediated processes could also have a confounding effect on uranium mobility in subsurface environments.

PIP-II Transfer Line Design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vivoli, A.

The U.S. Particle Physics Project Prioritization Panel (P5) report encouraged the realization of Fermilab's Proton Improvement Plan II (PIP-II) to support future neutrino programs in the United States. PIP-II aims at enhancing the capabilities of the Fermilab existing accelerator complex while simultaneously providing a flexible platform for its future upgrades. The central part of PIP-II project is the construction of a new 800 MeV H- Superconducting (SC) Linac together with upgrades of the Booster and Main Injector synchrotrons. New transfer lines will also be needed to deliver beam to the down-stream accelerators and facilities. In this paper we present themore » recent development of the design of the transfer lines discussing the principles that guided their design, the constraints and requirements imposed by the existing accelerator complex and the following modifications implemented to comply with a better understanding of the limitations and further requirements that emerged during the development of the project.« less

Occupational Pursuits: The Army and World War II Occupation Planning

DTIC Science & Technology

2010-03-01

Army became the dominant U.S. government agency in the interagency process concerning post-World War II occupation planning. Despite President ...the Army’s ability to create coherent internal doctrine, the relative weakness of civilian agencies, and the agenda and postwar goals of President ...Despite President Roosevelt’s own misgivings, shared by several influential members of his Cabinet, the Army nonetheless prevailed in shaping

Adolescent Health. Volume II: Background and the Effectiveness of Selected Prevention and Treatment Services [and] Indexes to Volumes I, II, and III.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Office of Technology Assessment.

This document, the second of three volumes in the U.S. Congress Office of Technology Assessment's "Adolescent Health" series, provides background information on aspects of adolescents' lives and examines the effectiveness of prevention and treatment interventions. Chapter 1, an introduction to this two-part document, provides a summary of the…

Teaching about Rosie the Riveter: The Role of Women during World War II.

ERIC Educational Resources Information Center

Anderson, Karen

1988-01-01

Discusses a neglected area of U.S. history: the impact of World War II on the role and status of women. Shows how women's work in the home and in the community assisted the national defense effort, and examined the way that changes in employment opportunities affected traditional ideas about women's roles and fostered the modern women's movement.…

Treatment of Japanese-American Internment During World War II in U.S. History Textbooks

ERIC Educational Resources Information Center

Ogawa, Masato

2004-01-01

The purpose of this study is to analyze the treatment of Japanese-American internment during World War II in high school United States history textbooks. Four reasons highlight the selection of this topic for study. First, this historical event was selected because a little over a year ago was the 60th anniversary of President Franklin D.…

Implementation of Title I and Title II-A Program Initiatives: Results from 2013-14. NCEE 2017-4014

ERIC Educational Resources Information Center

Troppe, Patricia; Milanowski, Anthony T.; Heid, Camilla; Gill, Brian; Ross, Christine

2017-01-01

This report describes the implementation of policies and initiatives supported by Title I and Title II-A of the federal Elementary and Secondary Education Act (ESEA) during the 2013-14 school year. Title I is one of the U.S. Department of Education's largest programs, accounting for $15 billion in the 2016 federal budget. Historically, Title I has…

75 FR 80773 - Takes of Marine Mammals Incidental to Specified Activities; Taking Marine Mammals Incidental to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-23

... Delta II, which is being withdrawn from service. The U.S. Air Force reports that sound pressures of the Delta II were slightly less than those from the Taurus I (Castor 120) as measured from the same point... conducted after one Delta IV launch in 2006. During this launch the digital audio tape (DAT) recorder was...

12 CFR 225.13 - Factors considered in acting on bank acquisition proposals.

Code of Federal Regulations, 2012 CFR

2012-01-01

... provided in § 211.24(c)(1)(ii) of the Board's Regulation K (12 CFR 211.24(c)(1)(ii)). (b) Other factors. In... 12 Banks and Banking 3 2012-01-01 2012-01-01 false Factors considered in acting on bank... under the Community Reinvestment Act of 1977 (12 U.S.C. 2901 et seq.) and regulations issued thereunder...

12 CFR 225.13 - Factors considered in acting on bank acquisition proposals.

Code of Federal Regulations, 2011 CFR

2011-01-01

... provided in § 211.24(c)(1)(ii) of the Board's Regulation K (12 CFR 211.24(c)(1)(ii)). (b) Other factors. In... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Factors considered in acting on bank... under the Community Reinvestment Act of 1977 (12 U.S.C. 2901 et seq.) and regulations issued thereunder...

Seminar on the Acquisition of Latin American Library Materials (13th, Lawrence, Kansas, June 20-22, 1968). Final Report and Working Papers. Vol. II.

ERIC Educational Resources Information Center

Jordan, Alma; Rovira, Carmen

The eight working papers used as documentation for the Thirteenth Seminar are included in volume II. They are: (1) "Progress Report on the Seminars on the Acquisition of Latin American Library Materials, 1968;" (2) "Significant Acquisitions of Latin American Material by U.S. Libraries, 1967/68;" (3) "A Report of…

38 CFR 3.315 - Basic eligibility determinations; dependents, loans, education.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... (Authority: 38 U.S.C. 101(4)(B)) (b) Loans. If a veteran of World War II the Korean conflict or the Vietnam... presumption of incurrence under § 3.304(b). Determinations based on World War II, Korean conflict and Vietnam... than 181 days of service on active duty as defined in §§ 36.4301 and 36.4501, eligibility of the...

38 CFR 3.315 - Basic eligibility determinations; dependents, loans, education.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... (Authority: 38 U.S.C. 101(4)(B)) (b) Loans. If a veteran of World War II the Korean conflict or the Vietnam... presumption of incurrence under § 3.304(b). Determinations based on World War II, Korean conflict and Vietnam... than 181 days of service on active duty as defined in §§ 36.4301 and 36.4501, eligibility of the...

38 CFR 3.315 - Basic eligibility determinations; dependents, loans, education.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... (Authority: 38 U.S.C. 101(4)(B)) (b) Loans. If a veteran of World War II the Korean conflict or the Vietnam... presumption of incurrence under § 3.304(b). Determinations based on World War II, Korean conflict and Vietnam... than 181 days of service on active duty as defined in §§ 36.4301 and 36.4501, eligibility of the...

38 CFR 3.315 - Basic eligibility determinations; dependents, loans, education.

Code of Federal Regulations, 2012 CFR

2012-07-01

.... (Authority: 38 U.S.C. 101(4)(B)) (b) Loans. If a veteran of World War II the Korean conflict or the Vietnam... presumption of incurrence under § 3.304(b). Determinations based on World War II, Korean conflict and Vietnam... than 181 days of service on active duty as defined in §§ 36.4301 and 36.4501, eligibility of the...

Rock Quality Designation (RQD) after Twenty Years.

DTIC Science & Technology

1989-02-01

strength, and seismic refraction velocity for prediction of single-tooth rippability with a D-8 dozer, all correlated by field rippability tests...Smith (1986) utilizes the RMR System to estimate rippability . Kirsten (1988) characterizes excavatability for trenching, digging, dozing, and...Lisbon, Portugal, Vol. 1, pp. II. 33 - II. 42. Smith, H.J., (1986), "Estimating Rippability by Rock Mass Classification," Proc. 27th U.S. Symposium on

77 FR 57072 - Proposed Information Collection; Comment Request; National Security and Critical Technology...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-17

... Request; National Security and Critical Technology Assessments of the U.S. Industrial Base AGENCY: Bureau... Federal agencies, conducts assessments of U.S. industrial base sectors deemed critical to U.S. national... needs of these critical market segments in order to maintain a strong U.S. industrial base. II. Method...

7 CFR 51.624 - U.S. Combination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Combination. 51.624 Section 51.624 Agriculture... § 51.624 U.S. Combination. “U.S. Combination” consists of a combination of U.S. No. 1 and U.S. No. 2 grapefruit: Provided, That the number of U.S. No. 2 fruits specified in § 51.628, Tables I and II, are not...

High-level extracellular protein production in Bacillus subtilis using an optimized dual-promoter expression system.

PubMed

Zhang, Kang; Su, Lingqia; Duan, Xuguo; Liu, Lina; Wu, Jing

2017-02-20

We recently constructed a Bacillus subtilis strain (CCTCC M 2016536) from which we had deleted the srfC, spoIIAC, nprE, aprE and amyE genes. This strain is capable of robust recombinant protein production and amenable to high-cell-density fermentation. Because the promoter is among the factors that influence the production of target proteins, optimization of the initial promoter, P amyQ from Bacillus amyloliquefaciens, should improve protein expression using this strain. This study was undertaken to develop a new, high-level expression system in B. subtilis CCTCC M 2016536. Using the enzyme β-cyclodextrin glycosyltransferase (β-CGTase) as a reporter protein and B. subtilis CCTCC M 2016536 as the host, nine plasmids equipped with single promoters were screened using shake-flask cultivation. The plasmid containing the P amyQ' promoter produced the greatest extracellular β-CGTase activity; 24.1 U/mL. Subsequently, six plasmids equipped with dual promoters were constructed and evaluated using this same method. The plasmid containing the dual promoter P HpaII -P amyQ' produced the highest extracellular β-CGTase activity (30.5 U/mL) and was relatively glucose repressed. The dual promoter P HpaII -P amyQ' also mediated substantial extracellular pullulanase (90.7 U/mL) and α-CGTase expression (9.5 U/mL) during shake-flask cultivation, demonstrating the general applicability of this system. Finally, the production of β-CGTase using the dual-promoter P HpaII -P amyQ' system was investigated in a 3-L fermenter. Extracellular expression of β-CGTase reached 571.2 U/mL (2.5 mg/mL), demonstrating the potential of this system for use in industrial applications. The dual-promoter P HpaII -P amyQ' system was found to support superior expression of extracellular proteins in B. subtilis CCTCC M 2016536. This system appears generally applicable and is amenable to scale-up.

Procollagen-III peptide and chronic viral C hepatitis.

PubMed

Jeffers, L J; Coelho-Little, M E; Cheinquer, H; Vargas, C; Civantos, F; Alvarez, L; Reddy, K R; Parker, T; de Medina, M; Li, X

1995-09-01

Chronic hepatitis develops in at least half of persons acutely infected with hepatitis C virus (HCV). Ten to 25% of these patients will develop cirrhosis. Serum procollagen-III peptide (PIIIP) may be of value in predicting the development of chronic active fibrogenic liver disease. It has been reported that in chronic viral C hepatitis, the levels of hepatitis C virus-RNA (HCV-RNA) correlate directly with the severity of hepatic histology and inversely with response to interferon therapy. The aims of this study were to correlate the level of PIIIP with HCV-RNA concentrations, ALT values, and histological severity in patients with chronic viral C hepatitis. Eighty-six patients with chronic C hepatitis were divided into three groups: group I (n = 34), mild chronic active hepatitis, group II (n = 25), moderate to severe chronic active hepatitis, and group III (n = 27), cirrhosis. HCV-RNA was measured by Quantiplex, and PIIIP was measured by radioimmunoassay-gnostic assay. Mean +/- SD level of ALT in group I was 114 +/- 48 U/L, group II was 169 +/- 115 U/L, and group III was 160 +/- 94 U/L. The mean +/- SD level of HCV-RNA in group I was 110 +/- 130 x 10(5) Eq/ml, in group II was 140 +/- 140 x 10(5) Eq/ml, and in group III was 70 +/- 80 x 105 Eq/ml. The mean +/- SD level of PIIIP in group I was 0.6 +/- 0.2 U/ml, in group II was 0.9 +/- 0.4 U/ml, and in group III was 1.2 +/- 0.6. There was a significant difference in the levels of PIIIP among the three groups (p = 0.0001). There was no correlation among ALT, HCV-RNA, and PIIIP in any of the three groups. PIIIP peptide determinations in patients with chronic viral C hepatitis are reflective of histological severity and may provide relatively noninvasive means of following disease progression.

Basic Parameters of Metal Behavior under High Rate Forming

DTIC Science & Technology

1962-03-01

1ii PHOTOGRAPH THIS SHEET II LEVELr• At-ký W •I)-_) -N INVENTORY z DOCUMENT IDENTIFICATION may. 6•t S]/ tp i - 0~o- o’•5,,? 3 ’ \\NAL- TR-/I. -a I .. ~1...TR 111.2/20- 3 BASIC PARAMETERS OF METAL BEHAVIOUR "> UNDER HIGH RATE FORMING L L j Fourth Interim Report to ell- L’,I I U. S. ARMY MATERIALS...RESEARCH AGENCY 1• I iiC::Ur:ui i 1,,i .:1 ’•:, 1 r/ n od I P,101c rolcso. Filing Subjects: I. Explosive forming 2. Dynamic behavior of metals 3 . High rate

An Analysis Plan for the ARCOMS II (Armor Combat Operations Model Support II) Experiment.

DTIC Science & Technology

1983-06-01

In order to facilitate Armor Combat Modeling, the data analysis shculd focus upon the methods which transform the data intc descriptive or predictive ...discussed in Chapter III tc predict the Farameter for probability of detection in time ŕt. This should be compared with the results of the N.4gh -t Vision...J 6A 46.) I-I 0 f U-CL 0~ z o -Z 06 09 03 v 0 0 SJldnYS 10 ON Ipgr Cp o LSTm n at emn itgas 4AA rI z ;A (AZ - 090.0 UlA0 -O ON 404 Fiur CAd &P CC

Land’s End: A History of the New Orleans District, U. S. Army Corps of Engineers, and Its Lifelong Battle with the Lower Mississippi and Other Rivers Wending Their Way to the Sea

DTIC Science & Technology

1979-01-01

Major Captain Major Captain U Col Major 1st II Malar Captain Majo r Major Major Ma jor Captain II Col Cotone l Major Colonel Major...tropical storms, society required artifice to survive in a region where nature might reasonably have asked a few more eons to finish a work of creation...Mississippi, and when this work was completed the mouth of Old River was sealed off. Meantime, a control structure at Morganza’ had been finished in

Modeling of Network Identification Capability.

DTIC Science & Technology

1986-07-01

3d Oa. (D .0 C 2-2 , , d .. . • . ... U9U, ’ W W w . w:. w . w L~~i...aftershock). 2. Pe p.. f. -o. p°. 𔃻 p’•.i l. mI I I + + i ..,L I + II ,,I-+ II I, qil + -]tIt -l + P ’L "P ’ "• , - . P " ",’I I"% %’ ° +"""" t...8217 % % , ’ ’,% ’. % . % ’.’ . . ’- *’-’. ’.’ . . ,° - . ...-.- " ,.."- . .. ’.. .’ -’ SSS-R-86-8033 Ile 1. Plot;’table limits i.e., the minimum ana max’mum varues of

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 14. (Nor Cal Aerospace-PHP Healthcare Corporation)

DTIC Science & Technology

1989-01-01

01111101000004 0101001011014 01 01-00101010010101010 41 it Ic - If 000000000000001 00 00 00 0000000- 00 000000000m0000000000000 cell IWN- 11 0 0 11 1 004 If I...3 If 411 W .1II 100 I0 0.10 < II CIS 0 I ’C- ) el4 of 0.4 ca 0I oc i 0 000 N3U MM I.0U mWL.WA A0 _CL.I 0 (.) 0- "I 0I 4CJ"Ŕ , 4"C4(40 4 NCJ""N0 I l 1

New reductions of the Astrographic Catalogue. Plate adjustments of the Algiers, Oxford I and II, and Vatican Zones.

NASA Astrophysics Data System (ADS)

Urban, S. E.; Martin, J. C.; Jackson, E. S.; Corbin, T. E.

1996-07-01

The U. S. Naval Observatory is in the process of making new reductions of the Astrographic Catalogue using a modern reference catalog, the ACRS, and new data analysis and reduction software. Currently ten AC zones have been reduced. This papers discusses the reduction models and results from the Algiers, Oxford I and II, and Vatican zones (those of the Cape zone are discussed elsewhere). The resulting star positions will be combined with those of the U.S. Naval Observatory's Twin Astrograph Catalog to produce a catalog of positions and proper motions in support of the Sloan Digital Sky Survey.

Influence of work clothing on physiological responses and performance during treadmill exercise and the Wildland Firefighter Pack Test.

PubMed

Phillips, Devin B; Ehnes, Cameron M; Welch, Bradley G; Lee, Lauren N; Simin, Irina; Petersen, Stewart R

2018-04-01

This study investigated physiological responses and performance during three separate exercise challenges (Parts I, II, and III) with wildland firefighting work clothing ensemble (boots and coveralls) and a 20.4 kg backpack in four conditions: U-EX (no pack, exercise clothing); L-EX (pack, exercise clothing); U-W (no pack, work clothing); and, L-W (pack and work clothing). Part I consisted of randomly-ordered graded exercise tests, on separate days, in U-EX, L-EX and L-W conditions. Part II consisted of randomly-ordered bouts of sub-maximal treadmill exercise in the four conditions. In Part III, subjects completed, in random-order on separate days, 4.83 km Pack Tests in L-EX or L-W conditions. In Part I, peak oxygen uptake was reduced (p < .05) in L-W. In Part II, mass-specific oxygen uptake was significantly higher in both work clothing conditions. In Part III, Pack Test time was slower (p < .05) in L-W. These results demonstrate the negative impact of work clothing and load carriage on physiological responses to exercise and performance. Copyright © 2017 Elsevier Ltd. All rights reserved.

Dollar Summary of Federal Supply Classification and Service Category by Company, FY88. Part 6. (Z129-Z299).

DTIC Science & Technology

1988-01-01

1 I I 0 a C I I I I I I I I I ON C4 Hzl HL H H H- H H H H- >HH H H HH > H 0 Z) Hw XI l - 0- C. En w 0 - 0 w u D - 0I 2O In 7 - - o 0 I FI m , C 0 u m...m V I 0 -4 w m l 0 0 C 0 Ii - Z Z (0 Q (A w () - n C II z ~ Iz or1 <- (0 0~ (0 >a .4 A. A. z4 s£ WH w 0c w) WC w0 w 0 0 El 0 0 a.I/I F- -4 u wA 0 0...P- " 22 "- < ɜ a 2 a A C A a 0 cI 0 0 04 04 x4 0. 0) w) tic 4w w4 4) 0 C 4 4 4) - ZO 3 C.) m£ nL HZZ Z H 22 1 2 . .3 C I.I VI I e I l I j I -4 .1 am

Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase

PubMed Central

Cozzoli, Anna; Liantonio, Antonella; Conte, Elena; Cannone, Maria; Massari, Ada Maria; Giustino, Arcangela; Scaramuzzi, Antonia; Pierno, Sabata; Mantuano, Paola; Capogrosso, Roberta Francesca; Camerino, Giulia Maria

2014-01-01

Angiotensin II (ANG II) plays a role in muscle wasting and remodeling; however, little evidence shows its direct effects on specific muscle functions. We presently investigated the acute in vitro effects of ANG II on resting ionic conductance and calcium homeostasis of mouse extensor digitorum longus (EDL) muscle fibers, based on previous findings that in vivo inhibition of ANG II counteracts the impairment of macroscopic ClC-1 chloride channel conductance (gCl) in the mdx mouse model of muscular dystrophy. By means of intracellular microelectrode recordings we found that ANG II reduced gCl in the nanomolar range and in a concentration-dependent manner (EC50 = 0.06 μM) meanwhile increasing potassium conductance (gK). Both effects were inhibited by the ANG II receptors type 1 (AT1)-receptor antagonist losartan and the protein kinase C inhibitor chelerythrine; no antagonism was observed with the AT2 antagonist PD123,319. The scavenger of reactive oxygen species (ROS) N-acetyl cysteine and the NADPH-oxidase (NOX) inhibitor apocynin also antagonized ANG II effects on resting ionic conductances; the ANG II-dependent gK increase was blocked by iberiotoxin, an inhibitor of calcium-activated potassium channels. ANG II also lowered the threshold for myofiber and muscle contraction. Both ANG II and the AT1 agonist L162,313 increased the intracellular calcium transients, measured by fura-2, with a two-step pattern. These latter effects were not observed in the presence of losartan and of the phospholipase C inhibitor U73122 and the in absence of extracellular calcium, disclosing a Gq-mediated calcium entry mechanism. The data show for the first time that the AT1-mediated ANG II pathway, also involving NOX and ROS, directly modulates ion channels and calcium homeostasis in adult myofibers. PMID:25080489

Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase.

PubMed

Cozzoli, Anna; Liantonio, Antonella; Conte, Elena; Cannone, Maria; Massari, Ada Maria; Giustino, Arcangela; Scaramuzzi, Antonia; Pierno, Sabata; Mantuano, Paola; Capogrosso, Roberta Francesca; Camerino, Giulia Maria; De Luca, Annamaria

2014-10-01

Angiotensin II (ANG II) plays a role in muscle wasting and remodeling; however, little evidence shows its direct effects on specific muscle functions. We presently investigated the acute in vitro effects of ANG II on resting ionic conductance and calcium homeostasis of mouse extensor digitorum longus (EDL) muscle fibers, based on previous findings that in vivo inhibition of ANG II counteracts the impairment of macroscopic ClC-1 chloride channel conductance (gCl) in the mdx mouse model of muscular dystrophy. By means of intracellular microelectrode recordings we found that ANG II reduced gCl in the nanomolar range and in a concentration-dependent manner (EC50 = 0.06 μM) meanwhile increasing potassium conductance (gK). Both effects were inhibited by the ANG II receptors type 1 (AT1)-receptor antagonist losartan and the protein kinase C inhibitor chelerythrine; no antagonism was observed with the AT2 antagonist PD123,319. The scavenger of reactive oxygen species (ROS) N-acetyl cysteine and the NADPH-oxidase (NOX) inhibitor apocynin also antagonized ANG II effects on resting ionic conductances; the ANG II-dependent gK increase was blocked by iberiotoxin, an inhibitor of calcium-activated potassium channels. ANG II also lowered the threshold for myofiber and muscle contraction. Both ANG II and the AT1 agonist L162,313 increased the intracellular calcium transients, measured by fura-2, with a two-step pattern. These latter effects were not observed in the presence of losartan and of the phospholipase C inhibitor U73122 and the in absence of extracellular calcium, disclosing a Gq-mediated calcium entry mechanism. The data show for the first time that the AT1-mediated ANG II pathway, also involving NOX and ROS, directly modulates ion channels and calcium homeostasis in adult myofibers. Copyright © 2014 the American Physiological Society.

Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells.

PubMed

Kim, Hyeon Ho; Sik Bang, Sung; Seok Choi, Jin; Han, Hogyu; Kim, Ik-Hwan

2005-06-08

Protein kinase C (PKC) plays an important role in the proliferation and differentiation of various cell types including normal and leukemic hematopoietic cells. Recently, various PKC modulators were used as a chemotherapeutic agent of leukemia. Decursin (1), a pyranocoumarin from Angelica gigas, exhibits the cytotoxic effects on various human cancer cell lines and in vitro PKC activation. For the development of more effective anticancer agents with PKC modulation activity, 11 decursin derivatives 2-12 were chemically synthesized and evaluated for their ability to act as a tumor-suppressing PKC activator and as an antagonist to phorbol 12-myristate 13-acetate (PMA), a tumor-promoting PKC activator. In the presence of phosphatidylserine (PS), all of 12 compounds 1-12 activated PKC (mainly alpha, beta, and gamma isozymes) but only three compounds 1-3 activated PKC even in the absence of PS. Six compounds 1-6 containing the coumarin structure were cytotoxic to human K562 erythroleukemia and U937 myeloleukemia cells. A cytotoxic mechanism of decursin and its derivatives was investigated using TUR cells, a PKC betaII-deficient variant of U937 cells. Among six compounds 1-6 with cytotoxicity to K562 and U937 leukemia cells, only three compounds 1-3 were cytotoxic to TUR cells. Therefore, compounds 1-3 and 4-6 inhibit the proliferation of leukemia cells in a PKC betaII-independent and dependent manner, respectively, indicating that the side chain of compounds determines the dependency of their cytotoxicity on PKC betaII. To further elucidate the cytotoxic mechanism of compounds 1 and 2, levels of PKC isozymes and generation of reactive oxygen species (ROS) were investigated. Compounds 1-2 induced the down-regulation of PKC alpha and betaII in K562 cells and the production of ROS in U937 cells. Thus, PKC and ROS are probably important factors in the cytotoxic mechanism of compounds 1-2. From these results, the structure-activity relationship of decursin and its derivatives is as follows: (i) the coumarin structure is required for anti-leukemic activity and (ii) the side chain is a determinant of PKC activation and the cytotoxic mechanism in leukemia cells.

The Value of the SYNTAX Score II in Predicting Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation.

PubMed

Ryan, Nicola; Nombela-Franco, Luis; Jiménez-Quevedo, Pilar; Biagioni, Corina; Salinas, Pablo; Aldazábal, Andrés; Cerrato, Enrico; Gonzalo, Nieves; Del Trigo, María; Núñez-Gil, Iván; Fernández-Ortiz, Antonio; Macaya, Carlos; Escaned, Javier

2017-11-27

The predictive value of the SYNTAX score (SS) for clinical outcomes after transcatheter aortic valve implantation (TAVI) is very limited and could potentially be improved by the combination of anatomic and clinical variables, the SS-II. We aimed to evaluate the value of the SS-II in predicting outcomes in patients undergoing TAVI. A total of 402 patients with severe symptomatic aortic stenosis undergoing transfemoral TAVI were included. Preprocedural TAVI angiograms were reviewed and the SS-I and SS-II were calculated using the SS algorithms. Patients were stratified in 3 groups according to SS-II tertiles. The coprimary endpoints were all-cause death and major adverse cardiovascular events (MACE), a composite of all-cause death, cerebrovascular event, or myocardial infarction at 1 year. Increased SS-II was associated with higher 30-day mortality (P=.036) and major bleeding (P=.015). The 1-year risk of death and MACE was higher among patients in the 3rd SS-II tertile (HR, 2.60; P=.002 and HR, 2.66; P<.001) and was similar among patients in the 2nd tertile (HR, 1.27; P=.507 and HR, 1.05; P=.895) compared with patients in the 1st tertile. The highest SS-II tertile was an independent predictor of long-term mortality (P=.046) and MACE (P=.001). The SS-II seems more suited to predict clinical outcomes in patients undergoing TAVI than the SS-I. Increased SS-II was associated with poorer clinical outcomes at 1 and 4 years post-TAVI, independently of the presence of coronary artery disease. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

AWIPS II in the University Community: Unidata's efforts and capabilities of the software

NASA Astrophysics Data System (ADS)

Ramamurthy, Mohan; James, Michael

2015-04-01

The Advanced Weather Interactive Processing System, version II (AWIPS II) is a weather forecasting, display and analysis tool that is used by the National Oceanic and Atmospheric Administration/National Weather Service (NOAA/NWS) and the National Centers for Environmental Prediction (NCEP) to ingest analyze and disseminate operational weather data. The AWIPS II software is built on a Service Oriented Architecture, takes advantage of open source software, and its design affords expandability, flexibility, and portability. Since many university meteorology programs are eager to use the same tools used by NWS forecasters, Unidata community interest in AWIPS II is high. The Unidata Program Center (UPC) has worked closely with NCEP staff during AWIPS II development in order to devise a way to make it available to the university. The Unidata AWIPS II software was released in beta form in 2014, and it incorporates a number of key changes to the baseline U. S. National Weather Service release to process and display additional data formats and run all components in a single-server standalone configuration. In addition to making available open-source instances of the software libraries that can be downloaded and run at any university, Unidata has also deployed the data-server side of AWIPS II, known as EDEX, in the Amazon Web Service and Microsoft Azure cloud environments. In this set up, universities receive all of the data from remote cloud instances, while they only have to run the AWIPS II client, known as CAVE, to analyze and visualize the data. In this presentation, we will describe Unidata's AWIPS II efforts, including the capabilities of the software in visualizing many different types of real-time meteorological data and its myriad uses in university and other settings.

Angiotensin II Inhibits the ROMK-like Small Conductance K Channel in Renal Cortical Collecting Duct during Dietary Potassium Restriction*

PubMed Central

Wei, Yuan; Zavilowitz, Beth; Satlin, Lisa M.; Wang, Wen-Hui

2010-01-01

Base-line urinary potassium secretion in the distal nephron is mediated by small conductance rat outer medullary K (ROMK)-like channels. We used the patch clamp technique applied to split-open cortical collecting ducts (CCDs) isolated from rats fed a normal potassium (NK) or low potassium (LK) diet to test the hypothesis that AngII directly inhibits ROMK channel activity. We found that AngII inhibited ROMK channel activity in LK but not NK rats in a dose-dependent manner. The AngII-induced reduction in channel activity was mediated by AT1 receptor (AT1R) binding, because pretreatment of CCDs with losartan but not PD123319 AT1 and AT2 receptor antagonists, respectively, blocked the response. Pretreatment of CCDs with U73122 and calphostin C, inhibitors of phospholipase C (PLC) and protein kinase C (PKC), respectively, abolished the AngII-induced decrease in ROMK channel activity, confirming a role of the PLC-PKC pathway in this response. Studies by others suggest that AngII stimulates an Src family protein-tyrosine kinase (PTK) via PKC-NADPH oxidase. PTK has been shown to regulate the ROMK channel. Inhibition of NADPH oxidase with diphenyliodonium abolished the inhibitory effect of AngII or the PKC activator phorbol 12-myristate 13-acetate on ROMK channels. Suppression of PTK by herbimycin A significantly attenuated the inhibitory effect of AngII on ROMK channel activity. We conclude that AngII inhibits ROMK channel activity through PKC-, NADPH oxidase-, and PTK-dependent pathways under conditions of dietary potassium restriction. PMID:17194699

Angiotensin II inhibits the ROMK-like small conductance K channel in renal cortical collecting duct during dietary potassium restriction.

PubMed

Wei, Yuan; Zavilowitz, Beth; Satlin, Lisa M; Wang, Wen-Hui

2007-03-02

Base-line urinary potassium secretion in the distal nephron is mediated by small conductance rat outer medullary K (ROMK)-like channels. We used the patch clamp technique applied to split-open cortical collecting ducts (CCDs) isolated from rats fed a normal potassium (NK) or low potassium (LK) diet to test the hypothesis that AngII directly inhibits ROMK channel activity. We found that AngII inhibited ROMK channel activity in LK but not NK rats in a dose-dependent manner. The AngII-induced reduction in channel activity was mediated by AT1 receptor (AT1R) binding, because pretreatment of CCDs with losartan but not PD123319 AT1 and AT2 receptor antagonists, respectively, blocked the response. Pretreatment of CCDs with U73122 and calphostin C, inhibitors of phospholipase C (PLC) and protein kinase C (PKC), respectively, abolished the AngII-induced decrease in ROMK channel activity, confirming a role of the PLC-PKC pathway in this response. Studies by others suggest that AngII stimulates an Src family protein-tyrosine kinase (PTK) via PKC-NADPH oxidase. PTK has been shown to regulate the ROMK channel. Inhibition of NADPH oxidase with diphenyliodonium abolished the inhibitory effect of AngII or the PKC activator phorbol 12-myristate 13-acetate on ROMK channels. Suppression of PTK by herbimycin A significantly attenuated the inhibitory effect of AngII on ROMK channel activity. We conclude that AngII inhibits ROMK channel activity through PKC-, NADPH oxidase-, and PTK-dependent pathways under conditions of dietary potassium restriction.

Failure of antioxidants to protect against angiotensin II-induced aortic rupture in aged apolipoprotein(E)-deficient mice.

PubMed

Jiang, F; Jones, G T; Dusting, G J

2007-11-01

Oxidative stress may be involved in the development of abdominal aortic aneurysms (AAAs). Previous studies indicate that antioxidants protect against AAA formation during chronic angiotensin (Ang) II infusion in apolipoprotein E-deficient (ApoE(0)) mice. We here examine if these protective effects also occurred in aged ApoE(0) mice. Male ApoE(0) mice (50-60 weeks) were randomly divided into 4 groups: saline, Ang II (1000 ng kg(-1) min(-1) for 4 weeks), Ang II plus antioxidants (0.1% vitamin E in food plus 0.1% vitamin C in drinking water), and Ang II plus losartan (30 mg kg(-1) day(-1)). Exogenous Ang II increased systolic blood pressure by 40 mmHg and resulted in the formation of pseudoaneurysms (rupture and extramural haematoma) in the abdominal aorta in 50% of animals. True aneurysmal dilatation was rarely observed. Antioxidants decreased systemic oxidative stress (plasma malondialdehyde), but had only minor effects on aortic rupture, relative to the complete prevention by losartan. Immunohistochemistry revealed strong matrix metalloproteinase-9 (MMP-9) expression in atherosclerotic plaques and at the sites of rupture. Antioxidants did not affect tumour necrosis factor-alpha-stimulated MMP-9 release from U937 cells. In addition, antioxidants had little effects on Ang II-induced renal dysfunction. In contrast to previous findings in younger mice, antioxidants had only minor effects on Ang II-induced aortic rupture in aged mice. Our results demonstrate that the pathological features of the aneurysmal remodelling induced by Ang II in old ApoE(0) mice are distinct from those of human AAA.

Electron transfer and atom exchange between aqueous Fe(II) and structural Fe(III) in clays. Role in U and Hg(II) transformations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scherer, Michelle

2016-08-31

During this project, we investigated Fe electron transfer and atom exchange between aqueous Fe(II) and structural Fe(III) in clay minerals. We used selective chemical extractions, enriched Fe isotope tracer experiments, computational molecular modeling, and Mössbauer spectroscopy. Our findings indicate that structural Fe(III) in clay minerals is reduced by aqueous Fe(II) and that electron transfer occurs when Fe(II) is sorbed to either basal planes and edge OH-groups of clay mineral. Findings from highly enriched isotope experiments suggest that up to 30 % of the Fe atoms in the structure of some clay minerals exhanges with aqueous Fe(II). First principles calculations usingmore » a small polaron hopping approach suggest surprisingly fast electron mobility at room temperature in a nontronite clay mineral and are consistent with temperature dependent Mössbauer data Fast electron mobility suggests that electrons may be able to conduct through the mineral fast enough to enable exchange of Fe between the aqueous phase and clay mineral structure. over the time periods we observed. Our findings suggest that Fe in clay minerals is not as stable as previously thought.« less

Modified method of simplest equation: Powerful tool for obtaining exact and approximate traveling-wave solutions of nonlinear PDEs

NASA Astrophysics Data System (ADS)

Vitanov, Nikolay K.

2011-03-01

We discuss the class of equations ∑i,j=0mAij(u){∂iu}/{∂ti}∂+∑k,l=0nBkl(u){∂ku}/{∂xk}∂=C(u) where Aij( u), Bkl( u) and C( u) are functions of u( x, t) as follows: (i) Aij, Bkl and C are polynomials of u; or (ii) Aij, Bkl and C can be reduced to polynomials of u by means of Taylor series for small values of u. For these two cases the above-mentioned class of equations consists of nonlinear PDEs with polynomial nonlinearities. We show that the modified method of simplest equation is powerful tool for obtaining exact traveling-wave solution of this class of equations. The balance equations for the sub-class of traveling-wave solutions of the investigated class of equations are obtained. We illustrate the method by obtaining exact traveling-wave solutions (i) of the Swift-Hohenberg equation and (ii) of the generalized Rayleigh equation for the cases when the extended tanh-equation or the equations of Bernoulli and Riccati are used as simplest equations.

15 CFR 748.11 - Statement by Ultimate Consignee and Purchaser.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., and denial, in whole or in part, of participation in U.S. exports or reexports. (ii) Except as specifically authorized by the U.S. Export Administration Regulations, or by written approval from the Bureau... contrary to the U.S. Export Administration Regulations. (iii) We understand that acceptance of this...

15 CFR 748.11 - Statement by Ultimate Consignee and Purchaser.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., and denial, in whole or in part, of participation in U.S. exports or reexports. (ii) Except as specifically authorized by the U.S. Export Administration Regulations, or by written approval from the Bureau... contrary to the U.S. Export Administration Regulations. (iii) We understand that acceptance of this...

15 CFR 748.11 - Statement by Ultimate Consignee and Purchaser.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., and denial, in whole or in part, of participation in U.S. exports or reexports. (ii) Except as specifically authorized by the U.S. Export Administration Regulations, or by written approval from the Bureau... contrary to the U.S. Export Administration Regulations. (iii) We understand that acceptance of this...

U.S. EPA, Pesticide Product Label, , 08/19/1988

EPA Pesticide Factsheets

2011-04-21

... FlO" '·1 I:. \\., d·· ,\\o:-t ; 'r,'·I.-I,·.j • .oF I~" I'''~: i"i !{' )"fl 1":1.1 ';':,1_· EI',\\ .. 10: :\\u.

Japan-U.S. Relations: Issues for Congress

DTIC Science & Technology

2009-06-03

resentful of Japan’s occupation policies and aggression in the World War II period. Despite underlying distrust, Tokyo’s relationships with Beijing and...prisoners during World War II, a charge that was later confirmed by the release of government documents. China In concert with the leadership in Beijing ...earthquake rescue experts then were dispatched to the hard-hit Sichuan province, the first foreign team that Beijing accepted. The official

In the High Cause of Human Freedom, 1935-1945. Dwight D. Eisenhower.

ERIC Educational Resources Information Center

Barbieri, Kim E.

For Dwight D. Eisenhower, World War II was not simply a war but a crusade in the high cause of human freedom. This publication, the third in a series of posters and curriculum materials on the life and times of Dwight D. Eisenhower, covers the events leading up to World War II and Eisenhower's rise to the rank of five star General of the U.S. Army…

Implementation of Title I and Title II-A Program Initiatives: Results from 2013-14. Executive Summary. NCEE 2017-4015

ERIC Educational Resources Information Center

Troppe, Patricia; Milanowski, Anthony T.; Heid, Camilla; Gill, Brian; Ross, Christine

2017-01-01

This report describes the implementation of policies and initiatives supported by Title I and Title II-A of the federal Elementary and Secondary Education Act (ESEA) during the 2013-14 school year. Title I is one of the U.S. Department of Education's largest programs, accounting for $15 billion in the 2016 federal budget. Historically, Title I has…

The Effectiveness of the Army and Navy Munitions Board during the Interwar Period

DTIC Science & Technology

2008-06-13

96  Comparison between the United States and the United Kingdom................................ 98  Comparison between the United States and Nazi ...industrial mobilization of Nazi Germany and the U.K. throughout the pre-war period and World War II. Specifically, the comparison will look at the...industrial mobilization of Nazi Germany in World War II, including armament production, industrial capabilities, the usage of raw materials, and labor

Acquisition, Image and Data Compression.

DTIC Science & Technology

1983-04-30

considered, self well to the freq.ency hcppe! signal arpli’a- ,i n. This loop aol Itn i ociltei w’efors are hown in Firs. la,h. 71;n r’tine wav ’-f, m...thei siiiillaiieiuts spacie midi slllitial tre(tivelicy 26. 1). .ui-.u.ii m~ill It. V. K. N’iu.a~ kiar Appl. Ot IS, ti673 filtering tt i-I ) sit .imls

Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness.

PubMed

Trachman, Robert J; Abdolahzadeh, Amir; Andreoni, Alessio; Cojocaru, Razvan; Knutson, Jay R; Ryckelynck, Michael; Unrau, Peter J; Ferré-D'Amaré, Adrian R

2018-05-24

Several RNA aptamers that bind small molecules and enhance their fluorescence have been successfully used to tag and track RNAs in vivo, but these genetically encodable tags have not yet achieved single-fluorophore resolution. Recently, Mango-II, an RNA that binds TO1-Biotin with ∼1 nM affinity and enhances its fluorescence by >1500-fold, was isolated by fluorescence selection from the pool that yielded the original RNA Mango. We determined the crystal structures of Mango-II in complex with two fluorophores, TO1-Biotin and TO3-Biotin, and found that despite their high affinity, the ligands adopt multiple distinct conformations, indicative of a binding pocket with modest stereoselectivity. Mutational analysis of the binding site led to Mango-II(A22U), which retains high affinity for TO1-Biotin but now discriminates >5-fold against TO3-biotin. Moreover, fluorescence enhancement of TO1-Biotin increases by 18%, while that of TO3-Biotin decreases by 25%. Crystallographic, spectroscopic, and analogue studies show that the A22U mutation improves conformational homogeneity and shape complementarity of the fluorophore-RNA interface. Our work demonstrates that even after extensive functional selection, aptamer RNAs can be further improved through structure-guided engineering.

Trypanosoma brucei RNA Editing Complex

PubMed Central

O'Hearn, Sean F.; Huang, Catherine E.; Hemann, Mike; Zhelonkina, Alevtina; Sollner-Webb, Barbara

2003-01-01

Maturation of Trypanosoma brucei mitochondrial mRNA involves massive posttranscriptional insertion and deletion of uridine residues. This RNA editing utilizes an enzymatic complex with seven major proteins, band I through band VII. We here use RNA interference (RNAi) to examine the band II and band V proteins. Band II is found essential for viability; it is needed to maintain the normal structure of the editing complex and to retain the band V ligase protein. Previously, band III was found essential for certain activities, including maintenance of the editing complex and retention of the band IV ligase protein. Thus, band II and band V form a protein pair with features analogous to the band III/band IV ligase pair. Since band V is specific for U insertion and since band IV is needed for U deletion, their parallel organization suggests that the editing complex has a pseudosymmetry. However, unlike the essential band IV ligase, RNAi to band V has only a morphological but no growth rate effect, suggesting that it is stimulatory but nonessential. Indeed, in vitro analysis of band V RNAi cell extract demonstrates that band IV can seal U insertion when band V is lacking. Thus, band IV ligase is the first activity of the basic editing complex shown able to serve in both forms of editing. Our studies also indicate that the U insertional portion may be less central in the editing complex than the corresponding U deletional portion. PMID:14560033

List of Inspected Tank Barges and Tankships

DTIC Science & Technology

1980-01-01

C) CC’ L-4 I-I. tD w V) 8.L T 4 I-I a 0 7 z 70 70 z7 ab 2! 7.I in -9 00 M T 0 x 0 0 t0 0 t3 M wA (0 a a ty m 0 0 LA UN U 0 C3 U’N C; N; ’ ’ ’ - N C...4 0 4 4C 13&; 51 a 2I x~ -i wt W tD . w3 9 1 0& C) 1 w I U4 ox’. 94. 0: .5 It o 5A (Z it CorI.- .5L LD D w U) N-CLPp0l 0w . 0 a. ts. m5. t49- -1 0...7IL a,& 1 -j & I m 7’ en.I.1 . 4. co 4 m I f r.) ’N a, 𔃺 a, U. U. N4.’ ,sL a .4 r .47 . 󈧭u 1. X- D2 4.. a. t. x 43 N P. tD Il ’DX 03 P X tm. I V , r

78 FR 42872 - Communication with the U.S. Copyright Office: Revised Addresses

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-18

... LIBRARY OF CONGRESS U.S. Copyright Office 37 CFR Parts 201 and 202 [Docket No. 2013-7] Communication with the U.S. Copyright Office: Revised Addresses AGENCY: U.S. Copyright Office, Library of..., LIBRARY OF CONGRESS 0 1. The heading of chapter II is revised to read as set forth above. PART 201...

Lifestyle Changes and Pressure Ulcer Prevention in Adults With Spinal Cord Injury in the Pressure Ulcer Prevention Study Lifestyle Intervention

PubMed Central

Ghaisas, Samruddhi; Pyatak, Elizabeth A.; Blanche, Erna; Clark, Florence

2015-01-01

Pressure ulcers (PrUs) are a major burden to patients with spinal cord injury (SCI), affecting their psychological, physical, and social well-being. Lifestyle choices are thought to contribute to the risk of developing PrUs. This article focuses on the interaction between lifestyle choices and the development of PrUs in community settings among participants in the University of Southern California–Rancho Los Amigos National Rehabilitation Center Pressure Ulcer Prevention Study (PUPS II), a randomized controlled trial of a lifestyle intervention for adults with SCI. We conducted a secondary cross-case analysis of treatment notes of 47 PUPS II participants and identified four patterns relating PrU development to lifestyle changes: positive PrU changes (e.g., healing PrUs) with positive lifestyle changes, negative or no PrU changes with positive lifestyle changes, positive PrU changes with minor lifestyle changes, and negative or no PrU changes with no lifestyle changes. We present case studies exemplifying each pattern. PMID:25553751

32 CFR 191.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Services Administration Order ADM 5420.71A; Executive Orders 11141; 11246 Part II, 11375, and 12086; Office.... 2014; 29 U.S.C. 631(b) and 633a; 5 U.S.C. chapters 43 and 72; Secretary of Defense Policy on Sexual...

Instructional Methods Tool

DTIC Science & Technology

2017-09-01

Research Product 2018-01 Instructional Methods Tool Jennifer S. Tucker U.S. Army Research Institute David R. James...Unclassified ii Research Product 2018-01 Instructional Methods Tool Jennifer S. Tucker U.S. Army Research Institute David R. James...1 RESEARCH OBJECTIVE ..............................................................................................................1 METHOD

Facility No. S362, view across the ramp U.S. Naval ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Facility No. S362, view across the ramp - U.S. Naval Base, Pearl Harbor, Seaplane Ramps - World War II Type, Southwest and west shore of Ford Island, near Wasp Boulevard, Pearl City, Honolulu County, HI

Randomized controlled trial of uncut Roux-en-Y vs Billroth II reconstruction after distal gastrectomy for gastric cancer: Which technique is better for avoiding biliary reflux and gastritis?

PubMed

Yang, Dong; He, Liang; Tong, Wei-Hua; Jia, Zhi-Fang; Su, Tong-Rong; Wang, Quan

2017-09-14

To identify which technique is better for avoiding biliary reflux and gastritis between uncut Roux-en-Y and Billroth II reconstruction. A total of 158 patients who underwent laparoscopy-assisted distal gastrectomy for gastric cancer at the First Hospital of Jilin University (Changchun, China) between February 2015 and February 2016 were randomized into two groups: uncut Roux-en-Y (group U) and Billroth II group (group B). Postoperative complications and relevant clinical data were compared between the two groups. According to the randomization table, each group included 79 patients. There was no significant difference in postoperative complications between groups U and B (7.6% vs 10.1%, P = 0.576). During the postoperative period, group U stomach pH values were lower than 7 and group B pH values were higher than 7. After 1 year of follow-up, group B presented a higher incidence of biliary reflux and alkaline gastritis. However, histopathology did not show a significant difference in gastritis diagnosis ( P = 0.278), and the amount of residual food and gain of weight between the groups were also not significantly different. At 3 mo there was no evidence of partial recanalization of uncut staple line, but at 1 year the incidence was 13%. Compared with Billroth II reconstruction, uncut Roux-en-Y reconstruction is secure and feasible, and can effectively reduce the incidence of alkaline reflux, residual gastritis, and heartburn. Despite the incidence of recanalization, uncut Roux-en-Y should be widely applied.

Syntheses and structures of [UO2( L)5](ClO4)2 and [U( L')4(H2O)4](ClO4)4 ( L is dimethylformamide, L' is N,N-dimethylcarbamide)

NASA Astrophysics Data System (ADS)

Serezhkin, V. N.; Vologzhanina, A. V.; Pushkin, D. V.; Astashkina, D. A.; Savchenkov, A. V.; Serezhkina, L. B.

2017-09-01

The reaction of aqueous solutions of uranyl perchlorate with selected organic amides was studied in the dark and under the sunlight. The complexes [UVIO2(C3H7NO)5](ClO4)2 ( I) and [UIV(C3H8N2O)4(H2O)4](ClO4)4 ( II), where C3H7NO is N,N-dimethylformamide ( Dmfa) and C3H8N2O is N,N-dimethylcarbamide ( a-Dmur), were studied by X-ray diffraction. Complex II and the complex UIV( s-Dmur)4(H2O)4(ClO4)4 ( III), where s-Dmur is N,N'-dimethylcarbamide, were studied by IR spectroscopy. Crystals I and II are composed of mononuclear [UO2( Dmfa)5]2+ and [U( Dmur)4(H2O)4]4+ groups as uranium-containing structural units belonging to the crystal-chemical groups AM 7 1 ( A = UVI, M 1 = O2- and Dmfa) and AM 8 1 ( A = UIV, M 1 = Dmur and H2O) of uranium complexes, respectively. The mononuclear uranium- containing complexes in the crystals of U(IV) and U(VI) perchlorates were found to obey the 14 neighbors rule.

Stem cells distribution, cellular proliferation and migration in the adult Austrolebias charrua brain.

PubMed

Torres-Pérez, Maximiliano; Rosillo, Juan Carlos; Berrosteguieta, Ines; Olivera-Bravo, Silvia; Casanova, Gabriela; García-Verdugo, José Manuel; Fernández, Anabel Sonia

2017-10-15

Our previous studies demonstrated that Austrolebias charrua annual fish is an excellent model to study adult brain cell proliferation and neurogenesis due to the presence of active and fast neurogenesis in several regions during its short lifespan. Our main goal was to identify and localize the cells that compose the neurogenic areas throughout the Austrolebias brain. To do this, we used two thymidine halogenated analogs to detect cell proliferation at different survival times: 5-chloro-2'-deoxyuridine (CldU) at 1day and 5-iodo-2'-deoxyuridine (IdU) at 30days. Three types of proliferating cells were identified: I - transient amplifying or fast cycling cells that uptake CldU; II - stem cells or slow cycling cells, that were labeled with both CldU and IdU and did not migrate; and III - migrant cells that uptake IdU. Mapping and 3D-reconstruction of labeled nuclei showed that type I and type II cells were preferentially found close to ventricle walls. Type III cells appeared widespread and migrating in tangential and radial routes. Use of proliferation markers together with Vimentin or Nestin evidenced that type II cells are the putative stem cells that are located at the ventricular lumen. Double label cells with IdU+ and NeuN or HuC/D allowed us identify migrant neurons. Quantitation of labeled nuclei indicates that the proportion of putative stem cells is around 10% in all regions of the brain. This percentage of stem cells suggests the existence of a constant brain cell population in Austrolebias charrua that seems functional to the maintainance of adult neurogenesis. Copyright © 2017 Elsevier B.V. All rights reserved.

Economics of immunization information systems in the United States: assessing costs and efficiency.

PubMed

Bartlett, Diana L; Molinari, Noelle-Angelique M; Ortega-Sanchez, Ismael R; Urquhart, Gary A

2006-08-22

One of the United States' national health objectives for 2010 is that 95% of children aged <6 years participate in fully operational population-based immunization information systems (IIS). Despite important progress, child participation in most IIS has increased slowly, in part due to limited economic knowledge about IIS operations. Should IIS need further improvement, characterizing costs and identifying factors that affect IIS efficiency become crucial. Data were collected from a national sampling frame of the 56 states/cities that received federal immunization grants under U.S. Public Health Service Act 317b and completed the federal 1999 Immunization Registry Annual Report. The sampling frame was stratified by IIS functional status, children's enrollment in the IIS, and whether the IIS had been developed as an independent system or was integrated into a larger system. These sites self-reported IIS developmental and operational program costs for calendar years 1998-2002 using a standardized data collection tool and underwent on-site interviews to verify reported data with information from the state/city financial management system and other financial records. A parametric cost-per-patient-record (CPR) model was estimated. The model assessed the impact of labor and non-labor resources used in development and operations tasks, as well as the impact of information technology, local providers' participation and compliance with federal IIS performance standards (e.g., ensuring the confidentiality and security of information, ensure timely vaccination data at the time of patient encounter, and produce official immunization records). Given the number of records minimizing CPR, the additional amount of resources needed to meet national health goals for the year 2010 was also calculated. Estimated CPR was as high as $10.30 and as low as $0.09 in operating IIS. About 20% of IIS had between 2.9 to 3.2 million records and showed CPR estimates of $0.09. Overall, CPR was highly sensitive to local providers' participation. To achieve the 2010 goals, additional aggregated costs were estimated to be $75.6 million nationwide. Efficiently increasing the number of records in IIS would require additional resources and careful consideration of various strategies to minimize CPR, such as boosting providers' participation.

Type 2 radio bursts, interplanetary shocks and energetic particle events

NASA Technical Reports Server (NTRS)

Cane, H. V.; Stone, R. G.

1982-01-01

Using the ISEE-3 radio astronomy experiment data 37 interplanetary (IP) type II bursts have been identified in the period September 1978 to December 1981. These events and the associated phenomena are listed. The events are preceded by intense, soft X ray events with long decay times (LDEs) and type II and/or type IV bursts at meter wavelengths. The meter wavelength type II bursts are usually intense and exhibit herringbone structure. The extension of the herringbone structure into the kilometer wavelength range results in the occurrence of a shock accelerated (SA) event. The majority of the interplanetary type II bursts are associated with energetic particle events. These results support other studies which indicate that energetic solar particles detected at 1 A.U. are generated by shock acceleration. From a preliminary analysis of the available data there appears to be a high correlation with white light coronal transients.

Energy Levels, wavelengths and hyperfine structure measurements of Sc II

NASA Astrophysics Data System (ADS)

Hala, Fnu; Nave, Gillian

2018-01-01

Lines of singly ionized Scandium (Sc II) along with other Iron group elements have been observed [1] in the region surrounding the massive star Eta Carinae [2,3] called the strontium filament (SrF). The last extensive analysis of Sc II was the four-decade old work of Johansson & Litzen [4], using low-resolution grating spectroscopy. To update and extend the Sc II spectra, we have made observation of Sc/Ar, Sc/Ne and Sc/Ge/Ar hollow cathode emission spectrum on the NIST high resolution FT700 UV/Vis and 2 m UV/Vis/IR Fourier transform spectrometers (FTS). More than 850 Sc II lines have been measured in the wavelength range of 187 nm to 3.2 μm. connecting a total of 152 energy levels. The present work also focuses to resolve hyperfine structure (HFS) in Sc II lines. We aim to obtain accurate transition wavelengths, improved energy levels and HFS constants of Sc II. The latest results from work in progress will be presented.Reference[1] Hartman H, Gull T, Johansson S and Smith N 2004 Astron. Astrophys. 419 215[2] Smith N, Morse J A and Gull T R 2004 Astrophys. J. 605 405[3] Davidson K and Humphreys R M 1997 Annu. Rev. Astron. Astrophys. 35[4] Johansson S and Litzén U 1980 Phys. Scr. 22 49

2013 Annual Site Inspection and Monitoring Report for Uranium Mill Tailings Radiation Control Act Title II Disposal Sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This report, in fulfillment of a license requirement, presents the results of long-term surveillance and maintenance activities conducted by the U.S. Department of Energy (DOE) Office of Legacy Management in 2013 at six uranium mill tailings disposal sites reclaimed under Title II of the Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978. These activities verified that the UMTRCA Title II disposal sites remain in compliance with license requirements. DOE manages six UMTRCA Title II disposal sites under a general license granted by the U.S. Nuclear Regulatory Commission (NRC) established at Title 10 Code of Federal Regulations Part 40.28. Reclamationmore » and site transition activities continue at other sites, and DOE ultimately expects to manage approximately 27 Title II disposal sites. Long-term surveillance and maintenance activities and services for these disposal sites include inspecting and maintaining the sites; monitoring environmental media and institutional controls; conducting any necessary corrective action; and performing administrative, records, stakeholder services, and other regulatory functions. Annual site inspections and monitoring are conducted in accordance with site-specific long-term surveillance plans (LTSPs) and procedures established by DOE to comply with license requirements. Each site inspection is performed to verify the integrity of visible features at the site; to identify changes or new conditions that may affect the long-term performance of the site; and to determine the need, if any, for maintenance, follow-up inspections, or corrective action. LTSPs and site compliance reports are available online at http://www.lm.doe.gov« less

Insights into the crystal-packing effects on the spin crossover of [Fe(II)(1-bpp)](2+)-based materials.

PubMed

Vela, Sergi; Novoa, Juan J; Ribas-Arino, Jordi

2014-12-28

Iron(II) complexes of the [Fe(II)(1-bpp2)](2+) type (1-bpp = 2,6-di(pyrazol-1-yl)pyridine) have been intensively investigated in the context of crystal engineering of switchable materials because their spin-crossover (SCO) properties dramatically depend on the counterions. Here, by means of DFT + U calculations at the molecular and solid state levels we provide a rationale for the different SCO behaviour of the BF4(-) and ClO4(-) salts of the parent complex; the former features Fe(II) complexes with a regular coordination geometry and undergoes a spin transition, whereas the Fe(II) complexes of the latter adopt a distorted structure and remain in the high-spin state at all temperatures. The different SCO behaviour of both salts can be explained on the basis of a combination of thermodynamic and kinetic effects. The shape of the SCO units at high temperature is thermodynamically controlled by the intermolecular interactions between the SCO units and counterions within the crystal. The spin trapping at low temperatures in the ClO4(-) salt, in turn, is traced back to a kinetic effect because our calculations have revealed the existence of a more stable polymorph having SCO units in their low-spin state that feature a regular structure. From the computational point of view, it is the first time that the U parameter is fine-tuned on the basis of CASPT2 calculations, thereby enabling an accurate description of the energetics of the spin transition at both molecular and solid-state levels.

Photographic copy of U.S. Army Corps of Engineers, Fort Worth, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Photographic copy of U.S. Army Corps of Engineers, Fort Worth, Texas, drawing (original located at Fort Hood, Texas), 1989 Site plan of North Fort Hood - Fort Hood, World War II Temporary Buildings, Killeen, Bell County, TX