Sample records for us ceq

  1. Massachusetts wants a tougher federal oil spill control plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Massachusetts wants a tougher federal oil spill control plan and has petitioned the U.S. Council on Environmental Quality (CEQ). The present oil spill contingency plan is inadequate, according to M. Dukakis (Gov. Mass.). The Massachusetts plan, which CEQ officials view favorably, would extend responsibility to the 200 mi fishing limit, provide for protection of birds, and set up an oil strike force on 24 hr alert.

  2. 40 CFR 1515.2 - About the Council on Environmental Quality (CEQ).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Quality (CEQ). 1515.2 Section 1515.2 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.2 About the Council on Environmental Quality (CEQ). The Council on Environmental Quality (“CEQ” or “the Council”) was created by the National Environmental Policy...

  3. 40 CFR 1515.2 - About the Council on Environmental Quality (CEQ).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Quality (CEQ). 1515.2 Section 1515.2 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.2 About the Council on Environmental Quality (CEQ). The Council on Environmental Quality (“CEQ” or “the Council”) was created by the National Environmental Policy...

  4. 40 CFR 1515.2 - About the Council on Environmental Quality (CEQ).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Quality (CEQ). 1515.2 Section 1515.2 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.2 About the Council on Environmental Quality (CEQ). The Council on Environmental Quality (“CEQ” or “the Council”) was created by the National Environmental Policy...

  5. 40 CFR 1515.2 - About the Council on Environmental Quality (CEQ).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Quality (CEQ). 1515.2 Section 1515.2 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.2 About the Council on Environmental Quality (CEQ). The Council on Environmental Quality (“CEQ” or “the Council”) was created by the National Environmental Policy...

  6. 75 FR 14135 - Pacific Coastal Salmon Recovery Fund

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... our NOAA Administrative Order 216-6 for NEPA, http://www.nepa.noaa.gov/NAO216_6_TOC.pdf , and the Council on Environmental Quality implementation regulations, http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq...

  7. 75 FR 4349 - National Estuarine Reserve System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... Administrative Order 216-6 for NEPA, http://www.nepa.noaa.gov/NAO216_6_TOC.pdf , and the Council on Environmental Quality implementation regulations, http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq.htm . Consequently, as...

  8. 75 FR 47261 - Availability of Grants Funds for Fiscal Year 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ....nepa.noaa.gov/NAO216_6_TOC.pdf , and the Council on Environmental Quality implementation regulations, http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq.htm . Consequently, as part of an applicant's package, and...

  9. 75 FR 13486 - Availability of Grant Funds for Fiscal Year 2010; Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    .../NAO216_6_TOC.pdf , and the Council on Environmental Quality implementation regulations, http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq.htm . Consequently, as part of an applicant's package, and under their...

  10. 75 FR 67684 - Availability of Grants Funds for Fiscal Year 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ....nepa.noaa.gov/NAO216_6_TOC.pdf , and the Council on Environmental Quality implementation regulations, http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq.htm . Consequently, as part of an applicant's package, and...

  11. 75 FR 67683 - Availability of Grants Funds for Fiscal Year 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... our NOAA Administrative Order 216-6 for NEPA http://www.nepa.noaa.gov/NAO216_6_TOC.pdf and the Council on Environmental Quality implementation regulations http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq.htm...

  12. 75 FR 55541 - NOAA Regional Ocean Partnership Funding Program-FY2011 Funding Competition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... Administrative Order 216-6 for NEPA, http://www.nepa.noaa.gov/NAO216_6_TOC.pdf and the Council on Environmental Quality implementation regulations, http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq.htm . Consequently, as...

  13. The Classroom Environment Questionnaire (CEQ): Development and preliminary structural validity.

    PubMed

    Lyons, Carissa; Brown, Ted; Bourke-Taylor, Helen

    2018-04-16

    Occupational therapists offer a unique perspective regarding the contribution of the environment to occupational performance. Therefore, a scale that measures the unique characteristics of the primary school classroom environment where children complete their daily schoolwork occupations is needed. The aim of this study was to develop and psychometrically evaluate a new teacher-report questionnaire that measures a number of environmental characteristics of primary school classrooms. Participants (N = 117) completed the Classroom Environment Questionnaire (CEQ), which utilises a 4-point Likert scale where teachers rate 51 environmental characteristics of their classroom. Teachers also rate the extent to which they believe the physical, social, temporal, institutional and cultural classroom environmental domains contribute to students' schoolwork performance using a 10-point scale. The structural validity of the CEQ was examined using principal component analysis (PCA). Inter-item correlations were examined using Pearson r correlations, while the internal consistency of the CEQ was assessed using Cronbach's alpha. PCA revealed the CEQ to be multidimensional, with 31 items loading onto nine viable factors, representing the unique nature of classroom environments. Based on the PCA results, 20 items were removed from the CEQ. Cronbach's alpha and correlation analysis indicated that most CEQ subsections had acceptable internal consistency (alpha range 0.70-0.82), with four subsections demonstrating a lower level of internal consistency (alpha range 0.55-0.69). Preliminary structural validity and internal consistency analysis findings confirm that the CEQ has potential to be a useful scale for professionals wishing to examine the unique characteristics of primary school classrooms that influence the occupational performance of students. Ongoing analyses will be undertaken to further explore the CEQ's validity and reliability. © 2018 Occupational Therapy Australia.

  14. 75 FR 30380 - NOAA's Office of Ocean Exploration and Research; Fiscal Year 2011 Ocean Exploration of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ....nepa.noaa.gov/NAO216_6_TOC.pdf , and the Council on Environmental Quality implementation regulations, http://ceq.eh.doe.gov/nepa/regs/ceq/toc_ceq.htm . Consequently, as part of an applicant's package, and...

  15. 40 CFR 1515.4 - CEQ FOIA Officials.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 1515.4 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.4 CEQ FOIA Officials. (a) The Chair shall appoint a Chief Freedom of Information Act... of Information Act and for receiving, routing and overseeing the processing of all Freedom of...

  16. 40 CFR 1515.4 - CEQ FOIA Officials.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 1515.4 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.4 CEQ FOIA Officials. (a) The Chair shall appoint a Chief Freedom of Information Act... of Information Act and for receiving, routing and overseeing the processing of all Freedom of...

  17. 40 CFR 1515.4 - CEQ FOIA Officials.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 1515.4 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.4 CEQ FOIA Officials. (a) The Chair shall appoint a Chief Freedom of Information Act... of Information Act and for receiving, routing and overseeing the processing of all Freedom of...

  18. 40 CFR 1515.4 - CEQ FOIA Officials.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 1515.4 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Organization of Ceq § 1515.4 CEQ FOIA Officials. (a) The Chair shall appoint a Chief Freedom of Information Act... of Information Act and for receiving, routing and overseeing the processing of all Freedom of...

  19. Aryl hydrocarbon receptor-mediated activity of atmospheric particulate matter from an urban and a rural site in Switzerland

    NASA Astrophysics Data System (ADS)

    Wenger, Daniela; Gerecke, Andreas C.; Heeb, Norbert V.; Hueglin, Christoph; Seiler, Cornelia; Haag, Regula; Naegeli, Hanspeter; Zenobi, Renato

    Atmospheric particulate matter (PM) is an air-suspended mixture of solid and liquid particles that vary in size, shape, and chemical composition. Long-term exposure to elevated concentrations of fine atmospheric particles is considered to pose a health threat to humans and animals. In this context, it has been hypothesized that toxic chemicals such as polycyclic aromatic hydrocarbons (PAHs) play an important role. Some PAHs are known to be carcinogenic and it has been shown that carcinogenic effects of PAHs are mediated by the aryl hydrocarbon receptor (AhR). In this study, PM1 was collected at a rural and an urban traffic site during an intense winter smog period, in which concentration of PM1 often exceeded 50 μg m -3. We applied an in vitro reporter gene assay (DR-CALUX) to detect and quantify PM1-associated chemicals that induce AhR-mediated gene expression. This activity was expressed as CALUX equivalents of 2,3,7,8-tetrachlorodibenzodioxin (PM-TCDD-CEQs). In addition, concentrations of PAHs in the PM1 extracts were determined using gas chromatography/high-resolution mass spectrometry. Concentrations of PM-TCDD-CEQs ranged from 10 to 85 pg m -3 and from 19 to 87 pg m -3 at the urban and rural site, respectively. By the use of known relative potency factors, the measured concentration of a PAH was converted into a PAH-TCDD-CEQ concentration. ΣPAH-TCDD-CEQ and PM-TCDD-CEQ were highly correlated at both sites ( r2 = 0.90 and 0.69). The calculated ΣPAH-TCDD-CEQs explain between 2% and 20% of the measured PM-TCDD-CEQs. Benzo[ k]fluoranthene was the most important PAH causing approximately 60% of the total ΣPAH-TCDD-CEQ activity. In contrast to NO, CO, PM10, and PM1, the concentration of PM-TCDD-CEQs showed no significant difference between the two sites. No indications were found that road traffic emissions caused elevated concentrations of PM-TCDD-CEQs at the urban traffic site.

  20. The Applicability of Course Experience Questionnaire for a Malaysian University Context

    ERIC Educational Resources Information Center

    Thien, Lei Mee; Ong, Mei Yean

    2016-01-01

    Purpose: The purpose of this study is to examine the applicability of Course Experience Questionnaire (CEQ) in a Malaysian university context. Design/methodology/approach: The CEQ was translated into Malay language using rigorous cross-cultural adaptation procedures. The Malay version CEQ was administered to 190 undergraduate students in one…

  1. 40 CFR 1515.6 - CEQ's response to a request.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 1515.6 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT... written request for information or records, under the Act, the CEQ FOIA Officer or his or her designee....5(b)(3). CEQ may make one request to the requester for information and toll the 20-day period while...

  2. 40 CFR 1515.6 - CEQ's response to a request.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 1515.6 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT... written request for information or records, under the Act, the CEQ FOIA Officer or his or her designee....5(b)(3). CEQ may make one request to the requester for information and toll the 20-day period while...

  3. 40 CFR 1515.6 - CEQ's response to a request.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 1515.6 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT... written request for information or records, under the Act, the CEQ FOIA Officer or his or her designee....5(b)(3). CEQ may make one request to the requester for information and toll the 20-day period while...

  4. 40 CFR 1515.6 - CEQ's response to a request.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 1515.6 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT... written request for information or records, under the Act, the CEQ FOIA Officer or his or her designee....5(b)(3). CEQ may make one request to the requester for information and toll the 20-day period while...

  5. 76 FR 3843 - Final Guidance for Federal Departments and Agencies on the Appropriate Use of Mitigation and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... 1970, is a fundamental tool used to harmonize our environmental, economic, and social aspirations and... Environmental Quality (CEQ) is charged with overseeing NEPA's implementation by Federal agencies. CEQ recognizes... implementation procedures.\\5\\ \\4\\ The Council on Environmental Quality (CEQ) Regulations for Implementing the...

  6. 10 CFR 51.14 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Definitions. 51.14 Section 51.14 Energy NUCLEAR REGULATORY... respect to any environmental impact involved in a proposal (or a reasonable alternative) for legislation... Environmental Quality (CEQ) established by Title II of NEPA. DOE means the U.S. Department of Energy or its duly...

  7. 10 CFR 51.14 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Definitions. 51.14 Section 51.14 Energy NUCLEAR REGULATORY... respect to any environmental impact involved in a proposal (or a reasonable alternative) for legislation... Environmental Quality (CEQ) established by Title II of NEPA. DOE means the U.S. Department of Energy or its duly...

  8. 40 CFR 1515.9 - Extending CEQ's time to respond.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Extending CEQ's time to respond. 1515... ACT PROCEDURES Procedures for Requesting Records § 1515.9 Extending CEQ's time to respond. (a) In... request (§§ 1515.6(a) and 1515.8(d)) may be extended by the Council for not more than 10 working days...

  9. 40 CFR 1515.9 - Extending CEQ's time to respond.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Extending CEQ's time to respond. 1515... ACT PROCEDURES Procedures for Requesting Records § 1515.9 Extending CEQ's time to respond. (a) In... request (§§ 1515.6(a) and 1515.8(d)) may be extended by the Council for not more than 10 working days...

  10. 40 CFR 1515.9 - Extending CEQ's time to respond.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Extending CEQ's time to respond. 1515... ACT PROCEDURES Procedures for Requesting Records § 1515.9 Extending CEQ's time to respond. (a) In... request (§§ 1515.6(a) and 1515.8(d)) may be extended by the Council for not more than 10 working days...

  11. 40 CFR 1515.9 - Extending CEQ's time to respond.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Extending CEQ's time to respond. 1515... ACT PROCEDURES Procedures for Requesting Records § 1515.9 Extending CEQ's time to respond. (a) In... request (§§ 1515.6(a) and 1515.8(d)) may be extended by the Council for not more than 10 working days...

  12. Putting Student Evaluations into Perspective: The Course Experience Quality and Satisfaction Model (CEQS)

    ERIC Educational Resources Information Center

    Grace, Debra; Weaven, Scott; Bodey, Kelli; Ross, Mitchell; Weaven, Keith

    2012-01-01

    Although not specifically designed for this purpose, the Course Experience Questionnaire (CEQ) continues to be used as a proxy for student satisfaction. This may be due to a lack of appropriate alternative measures, or a clear understanding of the relationship between quality and satisfaction. This study, therefore, examines the CEQ dimensions…

  13. Continuous equilibrium scores: factoring in the time before a fall.

    PubMed

    Wood, Scott J; Reschke, Millard F; Owen Black, F

    2012-07-01

    The equilibrium (EQ) score commonly used in computerized dynamic posturography is normalized between 0 and 100, with falls assigned a score of 0. The resulting mixed discrete-continuous distribution limits certain statistical analyses and treats all trials with falls equally. We propose a simple modification of the formula in which peak-to-peak sway data from trials with falls is scaled according the percent of the trial completed to derive a continuous equilibrium (cEQ) score. The cEQ scores for trials without falls remain unchanged from the original methodology. The cEQ factors in the time before a fall and results in a continuous variable retaining the central tendencies of the original EQ distribution. A random set of 5315 Sensory Organization Test trials were pooled that included 81 falls. A comparison of the original and cEQ distributions and their rank ordering demonstrated that trials with falls continue to constitute the lower range of scores with the cEQ methodology. The area under the receiver operating characteristic curve (0.997) demonstrates that the cEQ retained near-perfect discrimination between trials with and without falls. We conclude that the cEQ score provides the ability to discriminate between ballistic falls from falls that occur later in the trial. This approach of incorporating time and sway magnitude can be easily extended to enhance other balance tests that include fall data or incomplete trials. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. SU-F-T-124: Radiation Biological Equivalent Presentations OfLEM-1 and MKM Approaches in the Carbon-Ion Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hsi, W; Jiang, G; Sheng, Y

    Purpose: To study the correlations of the radiation biological equivalent doses (BED) along depth and lateral distance between LEM-1 and MKM approaches. Methods: In NIRS-MKM (Microdosimetric Kinetic Model) approach, the prescribed BED, referred as C-Eq, doses aims to present the relative biological effectiveness (RBE) for different energies of carbon-ions on a fixed 10% survival value of HCG cell with respect to convention X-ray. Instead of a fixed 10% survival, the BED doses of LEM-1 (Local Effect Model) approach, referred as X-Eq, aims to present the RBE over the whole survival curve of chordoma-like cell with alpha/beta ratio of 2.0. Themore » relationship of physical doses as a function of C-Eq and X-Eq doses were investigated along depth and lateral distance for various sizes of cubic targets in water irradiated by carbon-ions. Results: At the center of each cubic target, the trends between physical and C-Eq or X-Eq doses can be described by a linear and 2nd order polynomial functions, respectively. Using fit functions can then calculate a scaling factor between C-Eq and X-Eq doses to have similar physical doses. With equalized C-Eq and X-Eq doses at the depth of target center, over- and under-estimated X-Eq to C-Eq are seen for depths before and after the target center, respectively. Near the distal edge along depth, sharp rising of RBE value is observed for X-Eq, but sharp dropping of RBE value is observed for C-Eq. For lateral locations near and just outside 50% dose level, sharp raising of RBE value is also seen for X-Eq, while only minor increasing with fast dropping for C-Eq. Conclusion: An analytical function to model the differences between the CEq and X-Eq doses along depth and lateral distance need to further investigated to explain varied clinic outcome of specific cancers using two different approaches to calculated BED doses.« less

  15. 28 CFR 91.63 - Preparing an Environmental Impact Statement

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... variety of environmental impacts, the sensitive environmental nature of the proposed site, and/or the existence of highly controversial environmental impacts. (b) CEQ regulations. The CEQ regulations in 40 CFR...

  16. 28 CFR 91.63 - Preparing an Environmental Impact Statement

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... variety of environmental impacts, the sensitive environmental nature of the proposed site, and/or the existence of highly controversial environmental impacts. (b) CEQ regulations. The CEQ regulations in 40 CFR...

  17. 28 CFR 91.63 - Preparing an Environmental Impact Statement

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... variety of environmental impacts, the sensitive environmental nature of the proposed site, and/or the existence of highly controversial environmental impacts. (b) CEQ regulations. The CEQ regulations in 40 CFR...

  18. 28 CFR 91.63 - Preparing an Environmental Impact Statement

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... variety of environmental impacts, the sensitive environmental nature of the proposed site, and/or the existence of highly controversial environmental impacts. (b) CEQ regulations. The CEQ regulations in 40 CFR...

  19. 75 FR 78229 - Record of Decision for the U.S. Marine Corps East Coast Basing of the F-35B Aircraft

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ... States Code (U.S.C.) Section 4332(2)(c), the regulations of the Council on Environmental Quality (CEQ) for Implementing the Procedural Provisions of NEPA (40 Code of Federal Regulations [CFR] parts 1500... action, the Marine Corps will: (1) Construct and/or renovate airfield facilities and infrastructure...

  20. 75 FR 78229 - Record of Decision for the U.S. Marine Corps West Coast Basing of the F-35B Aircraft

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ... States Code (U.S.C.) Section 4332(2)(c), the regulations of the Council on Environmental Quality (CEQ) for Implementing the Procedural Provisions of NEPA (40 Code of Federal Regulations [CFR] parts 1500...) Construct and/or renovate airfield facilities and infrastructure necessary to accommodate and maintain the F...

  1. In Vivo Pharmacodynamics of Cefquinome in a Neutropenic Mouse Thigh Model of Streptococcus suis Serotype 2 at Varied Initial Inoculum Sizes

    PubMed Central

    Guo, Chunna; Liao, Xiaoping; Wang, Mingru; Wang, Feng; Yan, Chaoqun; Xiao, Xia; Sun, Jiang

    2015-01-01

    Streptococcus suis serotype 2 is an emerging zoonotic pathogen and causes severe disease in both pigs and human beings. Cefquinome (CEQ), a fourth-generation cephalosporin, exhibits broad-spectrum activity against Gram-positive bacteria such as S. suis. This study evaluated the in vitro and in vivo antimicrobial activities of CEQ against four strains of S. suis serotype 2 in a murine neutropenic thigh infection model. We investigated the effect of varied inoculum sizes (106 to 108 CFU/thigh) on the pharmacokinetic (PK)/pharmacodynamic (PD) indices and magnitudes of a particular PK/PD index or dose required for efficacy. Dose fractionation studies included total CEQ doses ranging from 0.625 to 640 mg/kg/24 h. Data were analyzed via a maximum effect (Emax) model using nonlinear regression. The PK/PD studies demonstrated that the percentage of time that serum drug levels were above the MIC of free drug (%ƒT>MIC) in a 24-h dosing interval was the primary index driving the efficacy of both inoculum sizes (R2 = 91% and R2 = 63%). CEQ doses of 2.5 and 40 mg/kg body weight produced prolonged postantibiotic effects (PAEs) of 2.45 to 8.55 h. Inoculum sizes had a significant influence on CEQ efficacy. Compared to the CEQ exposure and dosages in tests using standard inocula, a 4-fold dose (P = 0.006) and a 2-fold exposure time (P = 0.01) were required for a 1-log kill using large inocula of 108 CFU/thigh. PMID:26666923

  2. In Vivo Pharmacodynamics of Cefquinome in a Neutropenic Mouse Thigh Model of Streptococcus suis Serotype 2 at Varied Initial Inoculum Sizes.

    PubMed

    Guo, Chunna; Liao, Xiaoping; Wang, Mingru; Wang, Feng; Yan, Chaoqun; Xiao, Xia; Sun, Jiang; Liu, Yahong

    2016-02-01

    Streptococcus suis serotype 2 is an emerging zoonotic pathogen and causes severe disease in both pigs and human beings. Cefquinome (CEQ), a fourth-generation cephalosporin, exhibits broad-spectrum activity against Gram-positive bacteria such as S. suis. This study evaluated the in vitro and in vivo antimicrobial activities of CEQ against four strains of S. suis serotype 2 in a murine neutropenic thigh infection model. We investigated the effect of varied inoculum sizes (10(6) to 10(8) CFU/thigh) on the pharmacokinetic (PK)/pharmacodynamic (PD) indices and magnitudes of a particular PK/PD index or dose required for efficacy. Dose fractionation studies included total CEQ doses ranging from 0.625 to 640 mg/kg/24 h. Data were analyzed via a maximum effect (Emax) model using nonlinear regression. The PK/PD studies demonstrated that the percentage of time that serum drug levels were above the MIC of free drug (%ƒT>MIC) in a 24-h dosing interval was the primary index driving the efficacy of both inoculum sizes (R(2) = 91% and R(2) = 63%). CEQ doses of 2.5 and 40 mg/kg body weight produced prolonged postantibiotic effects (PAEs) of 2.45 to 8.55 h. Inoculum sizes had a significant influence on CEQ efficacy. Compared to the CEQ exposure and dosages in tests using standard inocula, a 4-fold dose (P = 0.006) and a 2-fold exposure time (P = 0.01) were required for a 1-log kill using large inocula of 10(8) CFU/thigh. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  3. 75 FR 6354 - NOAA Great Lakes Habitat Restoration Program Project Grants under the Great Lakes Restoration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ....gov/ , including our NOAA Administrative Order 216-6 for NEPA, http://www.nepa.noaa.gov/NAO216_6_TOC.../regs/ceq/toc_ceq.htm . Consequently, as part of an applicant's package, and under their description of...

  4. 40 CFR 1515.3 - CEQ organization.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false CEQ organization. 1515.3 Section 1515.3 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES... Act and the Environmental Quality Improvement Act give the Council the authority to hire any officers...

  5. 40 CFR 1515.3 - CEQ organization.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 33 2014-07-01 2014-07-01 false CEQ organization. 1515.3 Section 1515.3 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES... Act and the Environmental Quality Improvement Act give the Council the authority to hire any officers...

  6. 40 CFR 1515.3 - CEQ organization.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false CEQ organization. 1515.3 Section 1515.3 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES... Act and the Environmental Quality Improvement Act give the Council the authority to hire any officers...

  7. 40 CFR 1515.3 - CEQ organization.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false CEQ organization. 1515.3 Section 1515.3 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES... Act and the Environmental Quality Improvement Act give the Council the authority to hire any officers...

  8. 40 CFR 1515.14 - Other charges.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Other charges. 1515.14 Section 1515.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Costs § 1515.14 Other charges. CEQ may apply other charges, including the following: (a) Special charges. CEQ...

  9. 40 CFR 1515.14 - Other charges.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Other charges. 1515.14 Section 1515.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Costs § 1515.14 Other charges. CEQ may apply other charges, including the following: (a) Special charges. CEQ...

  10. 40 CFR 1515.14 - Other charges.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Other charges. 1515.14 Section 1515.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Costs § 1515.14 Other charges. CEQ may apply other charges, including the following: (a) Special charges. CEQ...

  11. 40 CFR 1515.14 - Other charges.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Other charges. 1515.14 Section 1515.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Costs § 1515.14 Other charges. CEQ may apply other charges, including the following: (a) Special charges. CEQ...

  12. Environmental Assessment Construction of a New Hazardous Cargo Pad Davis-Monthan AFB

    DTIC Science & Technology

    2002-11-07

    PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 355th Civil Engineer Squadron (CES/CEVA),710 Third Street,Davis-Monthan AFB,AZ,85707 8. PERFORMING...agency for certain projects. Details of the preparation of this EA are mandated by the Council of Enviromental Quality (CEQ) in the series of...Base, Tucson, Arizona." October 1996. James M. Montgomery, Consulting Engineers for US army Corps of Engineers , Omaha Dist., Apri11990

  13. 40 CFR 1515.3 - How is CEQ organized?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... staff. (d) The Council has no field or regional offices. (e) The Council has a public affairs office which is responsible for providing information to the general public, the Congress, and the press. If... “Public Affairs Office” of the Council at the address given in the next paragraph. Note: The CEQ public...

  14. An Analysis of Mode Effects in the 2010 Course Experience Questionnaire

    ERIC Educational Resources Information Center

    Carroll, David

    2011-01-01

    Historically, responses to the Course Experience Questionnaire (CEQ) were required to be collected by self-administered paper or online questionnaire to be eligible for official analysis. CEQ responses collected by telephone were excluded from the final analysis file to minimise the potential for bias due to mode effects: systematic variation in…

  15. 40 CFR 6.103 - Responsibilities of the NEPA and Responsible Officials.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... (8) Consult with Responsible Officials and CEQ regarding proposed changes to subpart A through C of...) Changes to the listings of types of actions that normally require the preparation of an EA or EIS. (9) Determine whether proposed changes are appropriate, and if so, coordinate with CEQ, pursuant to 40 CFR 1507...

  16. Online Student Evaluation Improves Course Experience Questionnaire Results in a Physiotherapy Program

    ERIC Educational Resources Information Center

    Tucker, Beatrice; Jones, Sue; Straker, Leon

    2008-01-01

    This paper reports the use of an online student evaluation system, Course Experience on the Web (CEW), in a physiotherapy program to improve their Course Experience Questionnaire (CEQ) results. CEW comprises a course survey instrument modeled on the CEQ and a tailored unit survey instrument. Closure of the feedback loop is integral in the CEW…

  17. Development of a Multifuel Individual/Squad Stove

    DTIC Science & Technology

    1990-02-01

    1 . Final Letter Report, Fix Verification Test of the MISS, U.S. Army CRTC , April 1989. m. Health Hazard Assessment, 4 April 1989, enclosed. n...CIVIL, 1 \\48ABIpPTR TECHNICAL REPORT __...__AD _ NATICK/TR-90/020 ceq DEVELOPMENT OF A00 O MULTIFUEL o INDIVIDUAL/SQUAD STOVE N I O BY DONALD W...NUMBERS PROGRAM PROJECT ITASK ~ WORK UNIT ELEMENT NO. NO. NO. ACCESSION NO. D5i48 24 1 146 TITLE (Include Security Classification) D 2 Development of a

  18. Preliminary validity of the modified Cigarette Evaluation Questionnaire in predicting the reinforcing effects of cigarettes that vary in nicotine content.

    PubMed

    Arger, Christopher A; Heil, Sarah H; Sigmon, Stacey C; Tidey, Jennifer W; Stitzer, Maxine L; Gaalema, Diann E; Durand, Hanna J; Bunn, Janice Y; Ruggieri, Elizabeth K; Higgins, Stephen T

    2017-12-01

    Validity studies evaluating self-report measures in relation to behavioral preference of cigarettes varying in nicotine content are needed. The current study examined the relationship between ratings on the modified Cigarette Evaluation Questionnaire (mCEQ) and the relative reinforcing effects of Spectrum research cigarettes (15.8, 5.2, 2.4, 0.4 mg per gram of tobacco). Data for this secondary analysis were obtained from a double-blind study (Higgins et al., 2017) evaluating the subjective and reinforcing effects of Spectrum cigarettes under acute smoking abstinence. Current smokers (N = 26) were recruited from three vulnerable smoking populations (economically disadvantaged women of reproductive age, opioid-maintained individuals, individuals with affective disorders). In Phase 1 (five sessions), the mCEQ (Satisfaction, Psychological Reward, Enjoyment of Respiratory Tract Sensations, Craving Reduction, Aversion subscales) was administered following ad lib smoking of Spectrum cigarettes and subscale differences scores were calculated by subtracting ratings of the 15.8 mg/g cigarette from ratings of the reduced nicotine content cigarettes. In Phase 2 (six sessions), participants completed six 2-dose concurrent choice tests. The relationship between mCEQ subscale difference scores from Phase 1 and nicotine dose choice from Phase 2 was examined using mixed-model repeated-measures analyses of variance. Higher Satisfaction and lower Aversion subscale difference scores were associated with choosing the 15.8 mg/g cigarette more than the 5.2, 2.4, and 0.4 mg/g cigarettes. Scores on the other mCEQ subscales were not associated with nicotine choice. These results provide support for validity of the mCEQ Satisfaction and Aversion subscales predicting the relative reinforcing effects and abuse liability of varying nicotine content cigarettes. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. The Challenging Experience Questionnaire: Characterization of challenging experiences with psilocybin mushrooms

    PubMed Central

    Barrett, Frederick S.; Bradstreet, Matthew P.; Leoutsakos, Jeannie-Marie S.; Johnson, Matthew W.; Griffiths, Roland R.

    2017-01-01

    Acute adverse psychological reactions to classic hallucinogens (“bad trips”, or “challenging experiences”), while usually benign with proper screening, preparation, and support in controlled settings, remain a safety concern in uncontrolled settings (such as illicit use contexts). Anecdotal and case reports suggest potential adverse acute symptoms including affective (panic, depressed mood), cognitive (confusion, feelings of losing sanity), and somatic (nausea, heart palpitation) symptoms. Responses to items from several hallucinogen-sensitive questionnaires (Hallucinogen Rating Scale, the States of Consciousness Questionnaire, and the 5-Dimensional Altered States of Consciousness questionnaire) in an internet survey of challenging experiences with the classic hallucinogen psilocybin were used to construct and validate a Challenging Experience Questionnaire (CEQ). The stand-alone CEQ was then validated in a separate sample. Seven CEQ factors (grief, fear, death, insanity, isolation, physical distress, and paranoia) provide a phenomenological profile of challenging aspects of experiences with psilocybin. Factor scores were associated with the difficulty, meaningfulness, spiritual significance, and change in well-being attributed to the challenging experiences. The factor structure did not differ based on gender or prior struggle with anxiety or depression. The CEQ provides a basis for future investigation of predictors and outcomes of challenging experiences with psilocybin, and should be explored as a measure of challenging experiences with the broad class of classic hallucinogens. PMID:27856683

  20. The role of ocean fluxes and radiative forcings in determining tropical rainfall shifts in RCP8.5 simulations

    NASA Astrophysics Data System (ADS)

    McFarlane, Ashly Ann; Frierson, Dargan M. W.

    2017-08-01

    We use Coupled Model Intercomparison Project global climate models forced with the Representative Concentration Pathway (RCP) 8.5 scenario to attribute tropical precipitation shifts under global warming scenarios and changes in cross-equatorial atmosphere heat transport (c-eq AHT) to changes in ocean and radiative fluxes. We find that the models tend to agree on the sign of c-eq AHT and change in precipitation asymmetry induced by each forcing, but not the magnitude. The ice-albedo feedback and aerosol emission reduction lead to the Northern Hemisphere warming, but this is countered by a reduction to the Atlantic Meridional Overturning Circulation northward heat transport and increased longwave leading to the multimodel mean change in precipitation asymmetry being approximately zero. None of the forcings considered, including aerosol cleanup, can account for more than 20% of the multimodel mean change in c-eq AHT alone.

  1. The Cannabis Expectancy Questionnaire for Men who have Sex with Men (CEQ-MSM): A measure of substance-related beliefs.

    PubMed

    Mullens, A B; Young, R McD; Dunne, M; Norton, G

    2010-06-01

    Substance-related expectancies are associated with substance use and post-substance use thoughts, feelings and behaviours. The expectancies held by specific cultural or sub-cultural groups have rarely been investigated. This research maps expectancies specific to gay and other men who have sex with men (MSM) and their relationship with substance patterns and behaviours following use, including sexual practices (e.g., unprotected anal intercourse). This study describes the development of a measure of such beliefs for cannabis, the Cannabis Expectancy Questionnaire for Men who have Sex with Men (CEQ-MSM). Items selected through a focus group and interviews were piloted on 180 self-identified gay or other MSM via an online questionnaire. Factor analysis revealed six distinct substance reinforcement domains ("Enhanced sexual experience", "Sexual negotiation", "Cognitive impairment", "Social and emotional facilitation", "Enhanced sexual desire", and "Sexual inhibition"). The scale was associated with consumption patterns of cannabis, and in a crucial test of discriminant validity not with the consumption of alcohol or stimulants. The CEQ-MSM represents a reliable and valid measure of outcome expectancies, related to cannabis among MSM. Future applications of the CEQ-MSM in health promotion, clinical settings and research may contribute to reducing harm associated with substance use among MSM, including HIV transmission. Copyright 2010 Elsevier Ltd. All rights reserved.

  2. Caffeine expectancy: instrument development in the Rasch measurement framework.

    PubMed

    Heinz, Adrienne J; Kassel, Jon D; Smith, Everett V

    2009-09-01

    Although caffeine is the most widely consumed psychoactive drug in the world, the mechanisms associated with consumption are not well understood. Nonetheless, outcome expectancies for caffeine use are thought to underlie caffeine's reinforcing properties. To date, however, there is no available, sufficient measure by which to assess caffeine expectancy. Therefore, the current study sought to develop such a measure employing Rasch measurement models. Unlike traditional measurement development techniques, Rasch analyses afford dynamic and interactive control of the analysis process and generate helpful information to guide instrument construction. A 5-stage developmental process is described, ultimately yielding a 37-item Caffeine Expectancy Questionnaire (CEQ) comprised of 4 factors representing "withdrawal symptoms," "positive effects," "acute negative effects," and "mood effects." Initial evaluation of the CEQ yielded sufficient evidence for various aspects of validity. Although additional research with more heterogeneous samples is required to further assess the measure's reliability and validity, the CEQ demonstrates potential with regard to its utility in experimental laboratory research and clinical application. 2009 APA, all rights reserved.

  3. Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP).

    PubMed

    Cubells, Joseph F; Feinn, Richard; Pearson, Deborah; Burda, Jeffrey; Tang, Yilang; Farrer, Lindsay A; Gelernter, Joel; Kranzler, Henry R

    2005-10-01

    Cocaine can induce transient psychotic symptoms. We examined the phenomenology of such cocaine-induced psychosis (CIP) using a modified version of the Scale for Assessment of Positive Symptoms (SAPS), a well-validated instrument for the assessment of schizophrenic psychosis. We developed a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP), based on the well-validated SAPS. We interviewed 243 unrelated cocaine-dependent adults using both the SAPS-CIP and an instrument for the identification of cocaine-induced paranoia, the Cocaine Experience Questionnaire (CEQ). One hundred and eighty-one (75%) of the subjects endorsed CIP using the CEQ. With the SAPS-CIP, hallucination (HAL) and delusion (DEL) scores correlated strongly, and the DEL domain showed excellent concurrent validity with the CEQ. We observed significant positive correlations, respectively, between severity of HAL and DEL, and lifetime number of episodes of cocaine use, and negative correlations with age at onset of cocaine use. The results suggest that CIP consists of transient delusional and hallucinatory symptoms, which tend to occur together and co-vary in severity. It appears that rating cocaine-induced paranoia alone (e.g., with the CEQ) can identify most subjects experiencing CIP. However, the SAPS-CIP is useful for quantifying the severity of CIP according to operational criteria. Our data provide additional evidence that CIP is a sensitizing response.

  4. A Prospective Investigation of Prenatal Mood and Childbirth Perceptions in an Ethnically Diverse, Low-Income Sample

    PubMed Central

    Congdon, Jayme L.; Adler, Nancy E.; Epel, Elissa S.; Laraia, Barbara A.; Bush, Nicole R.

    2017-01-01

    Introduction Few studies have examined prenatal mood as a means to identify women at risk for negative childbirth experiences. We explore associations between prenatal mood and birth perceptions in a socioeconomically diverse, American sample. Methods We conducted a prospective study of 136 predominantly low-income and ethnic minority women of mixed parity. Prenatal measures of perceived stress, pregnancy-related anxiety, and depressive symptoms were used to predict maternal perceptions of birth experiences one month postpartum using the Childbirth Experience Questionnaire (CEQ; 1). Results After adjusting for sociodemographic variables and mode of delivery, higher third trimester stress predicted worse CEQ total scores. This association was predominantly explained by two CEQ domains: own capacity (e.g. feelings of control and capability) and perceived safety. Pregnancy-related anxiety and depressive symptoms correlated with perceived stress, though neither independently predicted birth experience. Unplanned cesareans were associated with a worse CEQ total score. Vaginal delivery predicted greater perceived safety. Altogether, sociodemographic covariates, mode of delivery, and prenatal mood accounted for 35% of the variance in birth experience (p<.001). Discussion Our finding that prenatal stress explains a significant and likely clinically meaningful proportion of the variance in birth experience suggests that women perceive and recall their birth experiences through a lens that is partially determined by preexisting personal circumstances and emotional reserves. Since childbirth perceptions have implications for maternal and child health, patient satisfaction, and healthcare expenditures, these findings warrant consideration of prenatal stress screening to target intervention for women at risk for negative birth experiences. PMID:26948850

  5. A Prospective Investigation of Prenatal Mood and Childbirth Perceptions in an Ethnically Diverse, Low-Income Sample.

    PubMed

    Congdon, Jayme L; Adler, Nancy E; Epel, Elissa S; Laraia, Barbara A; Bush, Nicole R

    2016-06-01

    Few studies have examined prenatal mood as a means to identify women at risk for negative childbirth experiences. We explore associations between prenatal mood and birth perceptions in a socioeconomically diverse, American sample. We conducted a prospective study of 136 predominantly low-income and ethnic minority women of mixed parity. Prenatal measures of perceived stress, pregnancy-related anxiety, and depressive symptoms were used to predict maternal perceptions of birth experiences 1 month postpartum, using the childbirth experience questionnaire (CEQ; 1). After adjusting for sociodemographic variables and mode of delivery, higher third-trimester stress predicted worse CEQ total scores. This association was predominantly explained by two CEQ domains: own capacity (e.g., feelings of control and capability), and perceived safety. Pregnancy-related anxiety and depressive symptoms correlated with perceived stress, though neither independently predicted birth experience. An unplanned cesarean delivery was associated with a worse CEQ total score. Vaginal delivery predicted greater perceived safety. Altogether, sociodemographic covariates, mode of delivery, and prenatal mood accounted for 35 percent of the variance in birth experience (p < 0.001). Our finding that prenatal stress explains a significant and likely clinically meaningful proportion of the variance in birth experience suggests that women perceive and recall their birth experiences through a lens that is partially determined by preexisting personal circumstances and emotional reserves. Since childbirth perceptions have implications for maternal and child health, patient satisfaction, and health care expenditures, these findings warrant consideration of prenatal stress screening to target intervention for women at risk for negative birth experiences. © 2016 Wiley Periodicals, Inc.

  6. Correlates of the multidimensional construct of hypnotizability: paranormal belief, fantasy proneness, magical ideation, and dissociation.

    PubMed

    Dasse, Michelle N; Elkins, Gary R; Weaver, Charles A

    2015-01-01

    Hypnotizability is a multifaceted construct that may relate to multiple aspects of personality and beliefs. This study sought to address 4 known correlates of hypnotizability to aid in its understanding. Eighty undergraduates completed the Magical Ideation Scale (MIS), the Creative Experiences Questionnaire (CEQ), the Australian Sheep-Goat Scale (ASGS), and the Dissociative Experiences Scale (DES) and then were administered the Creative Imagination Scale (CIS). All 5 scales were significantly correlated. Participants higher in hypnotizability scored higher on the CEQ and the MIS. The findings demonstrate the influence of fantasy proneness and magical thinking on hypnotizability and support the theory that hypnotizability is a complex interaction of multiple traits.

  7. 7 CFR 1794.2 - Authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... authority from and is intended to be compliant with NEPA, CEQ Regulations for Implementing the Procedural.... 12898, Federal Actions to Address Environmental Justice in Minority Populations and Low-Income...

  8. 40 CFR 1515.10 - Obtaining available information.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the requested record or records can be downloaded or transferred intact to a computer disk or other... the public should be aware that communications between CEQ and the President (including communications...

  9. 40 CFR 1515.10 - Obtaining available information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the requested record or records can be downloaded or transferred intact to a computer disk or other... the public should be aware that communications between CEQ and the President (including communications...

  10. 40 CFR 1515.10 - Obtaining available information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the requested record or records can be downloaded or transferred intact to a computer disk or other... the public should be aware that communications between CEQ and the President (including communications...

  11. 7 CFR 799.11 - Expedited procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... THE NATIONAL ENVIRONMENTAL POLICY ACT § 799.11 Expedited procedures. Where emergency circumstances... of the NEPA regulations issued by CEQ, USDA, and FSA, FSA will, by working through the USDA Office of...

  12. 32 CFR 651.51 - The final phase.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., cannot or will not proceed unless other actions are previously or simultaneously taken, are... indicated in the preliminary phase. (2) Prescribe overall page limits for the EIS in accordance with the CEQ...

  13. 32 CFR 651.51 - The final phase.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., cannot or will not proceed unless other actions are previously or simultaneously taken, are... indicated in the preliminary phase. (2) Prescribe overall page limits for the EIS in accordance with the CEQ...

  14. 14 CFR 1216.314 - Tiering.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... are the subject of an environmental impact statement and which represents projects of broad scope may... “Tiering” (§ 1508.28 of the CEQ Regulations) of environmental impact statements to relate such broad and...

  15. 14 CFR 1216.314 - Tiering.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... are the subject of an environmental impact statement and which represents projects of broad scope may... “Tiering” (§ 1508.28 of the CEQ Regulations) of environmental impact statements to relate such broad and...

  16. 14 CFR 1216.314 - Tiering.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... are the subject of an environmental impact statement and which represents projects of broad scope may... “Tiering” (§ 1508.28 of the CEQ Regulations) of environmental impact statements to relate such broad and...

  17. 41 CFR 102-76.45 - What procedures must Federal agencies follow to implement the requirements of NEPA?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... MANAGEMENT REGULATION REAL PROPERTY 76-DESIGN AND CONSTRUCTION Design and Construction National Environmental... standards that they have promulgated to implement CEQ's regulations. Sustainable Development ...

  18. 41 CFR 102-76.45 - What procedures must Federal agencies follow to implement the requirements of NEPA?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... MANAGEMENT REGULATION REAL PROPERTY 76-DESIGN AND CONSTRUCTION Design and Construction National Environmental... standards that they have promulgated to implement CEQ's regulations. Sustainable Development ...

  19. 41 CFR 102-76.45 - What procedures must Federal agencies follow to implement the requirements of NEPA?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... MANAGEMENT REGULATION REAL PROPERTY 76-DESIGN AND CONSTRUCTION Design and Construction National Environmental... standards that they have promulgated to implement CEQ's regulations. Sustainable Development ...

  20. 41 CFR 102-76.45 - What procedures must Federal agencies follow to implement the requirements of NEPA?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... MANAGEMENT REGULATION REAL PROPERTY 76-DESIGN AND CONSTRUCTION Design and Construction National Environmental... standards that they have promulgated to implement CEQ's regulations. Sustainable Development ...

  1. 38 CFR 26.1 - Issuance and purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CEQ Regulations, 40 CFR parts 1500-1508), and Executive Order 11514, March 5, 1970, as amended by Executive Order 11991, May 24, 1977. This part shall provide guidance to officials of the Department of...

  2. 75 FR 42598 - Modification of Restricted Area R-3404; Crane, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    .... Navy prepared and published a Final Environmental Assessment (FEA) in June 2008 that analyzed the... Significant Impact (FONSI) based on the results of the FEA. In accordance with applicable CEQ regulations (40...

  3. 75 FR 65320 - Environmental Impact Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... Eight Allotments, Black Hills National Forest, Pennington and Custer Counties, SD, Wait Period Ends: 11... necessary under Section 1506.3(b) of the CEQ Regulations. EIS No. 20100416, Draft EIS, WAPA, CA, Rice Solar...

  4. Clinton creates environment post

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Begley, R.

    Raising the importance of environmental considerations in all federal policy, President Clinton is creating a new White House Office of Environmental Policy and renewing his pledge to elevate the Environmental Protection Agency to a Cabinet-level position. The new office will coordinate environmental policy throughout the federal government, working with the security, economics, and domestic policy councils, as well as relevant federal agenies. Its duties will include addressing global environmental problems and promoting green' technologies. Pending Congressional approval, Clinton plans to dismantle the Council on Environmental Quality (CEQ). Sen. Max Baucus (D., MT), chairman of the Senate Environment Committee, cautiously saysmore » he needs to review how CEQ's many important functions' will be handled by the new organization. Clinton also dismantled former Vice President Quayle's Competitiveness Council, saying it is closed, and so is the back door the polluters used to get out from under our laws.'« less

  5. Validation of the Cannabis Expectancy Questionnaire (CEQ) in adult cannabis users in treatment.

    PubMed

    Connor, Jason P; Gullo, Matthew J; Feeney, Gerald F X; Young, Ross McD

    2011-06-01

    Outcome expectancies are a key cognitive construct in the etiology, assessment and treatment of Substance Use Disorders. There is a research and clinical need for a cannabis expectancy measure validated in a clinical sample of cannabis users. The Cannabis Expectancy Questionnaire (CEQ) was subjected to exploratory (n=501, mean age 27.45, 78% male) and confirmatory (n=505, mean age 27.69, 78% male) factor analysis in two separate samples of cannabis users attending an outpatient cannabis treatment program. Weekly cannabis consumption was clinically assessed and patients completed the Severity of Dependence Scale-Cannabis (SDS-C) and the General Health Questionnaire (GHQ-28). Two factors representing Negative Cannabis Expectancies and Positive Cannabis Expectancies were identified. These provided a robust statistical and conceptual fit for the data. Internal reliabilities were high. Negative expectancies were associated with greater dependence severity (as measured by the SDS) and positive expectancies with higher consumption. The interaction of positive and negative expectancies was consistently significantly associated with self-reported functioning across all four GHQ-28 scales (Somatic Concerns, Anxiety, Social Dysfunction and Depression). Specifically, within the context of high positive cannabis expectancy, higher negative expectancy was predictive of more impaired functioning. By contrast, within the context of low positive cannabis expectancy, higher negative expectancy was predictive of better functioning. The CEQ is the first cannabis expectancy measure to be validated in a sample of cannabis users in treatment. Negative and positive cannabis expectancy domains were uniquely associated with consumption, dependence severity and self-reported mental health functioning. Crown Copyright © 2010. Published by Elsevier Ireland Ltd. All rights reserved.

  6. Self-organization in a simple model of adaptive agents playing 2×2 games with arbitrary payoff matrices

    NASA Astrophysics Data System (ADS)

    Fort, H.; Viola, S.

    2004-03-01

    We analyze, both analytically and numerically, the self-organization of a system of “selfish” adaptive agents playing an arbitrary iterated pairwise game (defined by a 2×2 payoff matrix). Examples of possible games to play are the prisoner’s dilemma (PD) game, the chicken game, the hero game, etc. The agents have no memory, use strategies not based on direct reciprocity nor “tags” and are chosen at random, i.e., geographical vicinity is neglected. They can play two possible strategies: cooperate (C) or defect (D). The players measure their success by comparing their utilities with an estimate for the expected benefits and update their strategy following a simple rule. Two versions of the model are studied: (1) the deterministic version (the agents are either in definite states C or D) and (2) the stochastic version (the agents have a probability c of playing C). Using a general master equation we compute the equilibrium states into which the system self-organizes, characterized by their average probability of cooperation ceq. Depending on the payoff matrix, we show that ceq can take five different values. We also consider the mixing of agents using two different payoff matrices and show that any value of ceq can be reached by tuning the proportions of agents using each payoff matrix. In particular, this can be used as a way to simulate the effect of a fraction d of “antisocial” individuals—incapable of realizing any value to cooperation—on the cooperative regime hold by a population of neutral or “normal” agents.

  7. Self-organization in a simple model of adaptive agents playing 2 x 2 games with arbitrary payoff matrices.

    PubMed

    Fort, H; Viola, S

    2004-03-01

    We analyze, both analytically and numerically, the self-organization of a system of "selfish" adaptive agents playing an arbitrary iterated pairwise game (defined by a 2 x 2 payoff matrix). Examples of possible games to play are the prisoner's dilemma (PD) game, the chicken game, the hero game, etc. The agents have no memory, use strategies not based on direct reciprocity nor "tags" and are chosen at random, i.e., geographical vicinity is neglected. They can play two possible strategies: cooperate (C) or defect (D). The players measure their success by comparing their utilities with an estimate for the expected benefits and update their strategy following a simple rule. Two versions of the model are studied: (1) the deterministic version (the agents are either in definite states C or D) and (2) the stochastic version (the agents have a probability c of playing C). Using a general master equation we compute the equilibrium states into which the system self-organizes, characterized by their average probability of cooperation c(eq). Depending on the payoff matrix, we show that c(eq) can take five different values. We also consider the mixing of agents using two different payoff matrices and show that any value of c(eq) can be reached by tuning the proportions of agents using each payoff matrix. In particular, this can be used as a way to simulate the effect of a fraction d of "antisocial" individuals--incapable of realizing any value to cooperation--on the cooperative regime hold by a population of neutral or "normal" agents.

  8. Primary weathering rates, water transit times, and concentration-discharge relations: A theoretical analysis for the critical zone

    NASA Astrophysics Data System (ADS)

    Ameli, Ali A.; Beven, Keith; Erlandsson, Martin; Creed, Irena F.; McDonnell, Jeffrey J.; Bishop, Kevin

    2017-01-01

    The permeability architecture of the critical zone exerts a major influence on the hydrogeochemistry of the critical zone. Water flow path dynamics drive the spatiotemporal pattern of geochemical evolution and resulting streamflow concentration-discharge (C-Q) relation, but these flow paths are complex and difficult to map quantitatively. Here we couple a new integrated flow and particle tracking transport model with a general reversible Transition State Theory style dissolution rate law to explore theoretically how C-Q relations and concentration in the critical zone respond to decline in saturated hydraulic conductivity (Ks) with soil depth. We do this for a range of flow rates and mineral reaction kinetics. Our results show that for minerals with a high ratio of equilibrium concentration (Ceq) to intrinsic weathering rate (Rmax), vertical heterogeneity in Ks enhances the gradient of weathering-derived solute concentration in the critical zone and strengthens the inverse stream C-Q relation. As CeqRmax decreases, the spatial distribution of concentration in the critical zone becomes more uniform for a wide range of flow rates, and stream C-Q relation approaches chemostatic behavior, regardless of the degree of vertical heterogeneity in Ks. These findings suggest that the transport-controlled mechanisms in the hillslope can lead to chemostatic C-Q relations in the stream while the hillslope surface reaction-controlled mechanisms are associated with an inverse stream C-Q relation. In addition, as CeqRmax decreases, the concentration in the critical zone and stream become less dependent on groundwater age (or transit time).

  9. 28 CFR 61.1 - Background.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY... 102(2) of NEPA contains certain procedural requirements directed toward the attainment of such goals... regulations to implement the procedural provisions of NEPA. Accordingly, CEQ issued final NEPA regulations, 40...

  10. 28 CFR 61.1 - Background.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY... 102(2) of NEPA contains certain procedural requirements directed toward the attainment of such goals... regulations to implement the procedural provisions of NEPA. Accordingly, CEQ issued final NEPA regulations, 40...

  11. 28 CFR 61.1 - Background.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY... 102(2) of NEPA contains certain procedural requirements directed toward the attainment of such goals... regulations to implement the procedural provisions of NEPA. Accordingly, CEQ issued final NEPA regulations, 40...

  12. 28 CFR 61.1 - Background.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY... 102(2) of NEPA contains certain procedural requirements directed toward the attainment of such goals... regulations to implement the procedural provisions of NEPA. Accordingly, CEQ issued final NEPA regulations, 40...

  13. 28 CFR 61.1 - Background.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY... 102(2) of NEPA contains certain procedural requirements directed toward the attainment of such goals... regulations to implement the procedural provisions of NEPA. Accordingly, CEQ issued final NEPA regulations, 40...

  14. 40 CFR 1515.2 - What is the Council on Environmental Quality (CEQ)?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Environmental Quality, March 5, 1970, as amended by Executive Order 11991, May 24, 1977. (b) The Council's... Information Act. This index is updated and published in the Federal Register quarterly, starting in 1976. The...

  15. Environmental Justice Guidance Under National Environmental Policy Act (NEPA), by the Council on Environmental Quality, 1997

    EPA Pesticide Factsheets

    CEQ, in consultation with EPA and other affected agencies, has developed this guidance to further assist Federal agencies with their NEPA procedures so that environmental justice concerns are effectively identified and addressed.

  16. 36 CFR 907.10 - Categorical exclusion.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and environmental assessments. (c) Changes to the list of categorical exclusion. (1) The PADC List of... ENVIRONMENTAL QUALITY § 907.10 Categorical exclusion. The CEQ Regulations provide for the categorical exclusion... human environment. Therefore, neither an environmental assessment nor an environmental impact statement...

  17. 12 CFR 1815.110 - Categorical exclusion.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ENVIRONMENTAL QUALITY § 1815.110 Categorical exclusion. The CEQ regulations provide for the categorical..., equipment, supplies and services; space acquisition; property management; and security); (b) Actions... residential; (3) The estimated cost of rehabilitation is less than 75 percent of the total estimated cost of...

  18. 36 CFR 907.10 - Categorical exclusion.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Categorical exclusion. 907.10 Section 907.10 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION ENVIRONMENTAL QUALITY § 907.10 Categorical exclusion. The CEQ Regulations provide for the categorical exclusion...

  19. 75 FR 8045 - National Environmental Policy Act (NEPA) Draft Guidance, Establishing, Applying, and Revising...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... COUNCIL ON ENVIRONMENTAL QUALITY National Environmental Policy Act (NEPA) Draft Guidance...: Council on Environmental Quality. ACTION: Notice of Availability, Draft Guidance, ``Establishing, Applying... February 18, 2010, the Council on Environmental Quality (CEQ) announced four steps to modernize...

  20. 14 CFR 1216.300 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... policy are available on NASA's Public Portal at http://www.nasa.gov/agency/nepa/(under NEPA Process). ... implements NEPA, setting forth NASA's policies and procedures for the early integration of environmental considerations into planning and decision making. (b) Through this subpart, NASA adopts the CEQ regulations...

  1. 28 CFR 91.54 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... major federal action that might significantly impact the quality of the human environment. The CEQ... activities that may significantly impact the environment. (c) Projects. Although VOI/TIS money cannot be used... Impact Review Procedures for VOI/TIS Grant Program Application to Voi/tis Grant Program § 91.54...

  2. 7 CFR 1940.332 - Emergencies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... an emergency circumstance makes it necessary to take an action with significant environmental impact... CEQ's regulations limit such arrangements to actions necessary to control the immediate impacts of the... circumstance is defined as one involving an immediate or imminent danger to public health or safety. (b) Action...

  3. 7 CFR 1940.332 - Emergencies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... an emergency circumstance makes it necessary to take an action with significant environmental impact... CEQ's regulations limit such arrangements to actions necessary to control the immediate impacts of the... circumstance is defined as one involving an immediate or imminent danger to public health or safety. (b) Action...

  4. 7 CFR 1940.332 - Emergencies.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... an emergency circumstance makes it necessary to take an action with significant environmental impact... CEQ's regulations limit such arrangements to actions necessary to control the immediate impacts of the... circumstance is defined as one involving an immediate or imminent danger to public health or safety. (b) Action...

  5. 7 CFR 1940.332 - Emergencies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... an emergency circumstance makes it necessary to take an action with significant environmental impact... CEQ's regulations limit such arrangements to actions necessary to control the immediate impacts of the... circumstance is defined as one involving an immediate or imminent danger to public health or safety. (b) Action...

  6. 7 CFR 1940.332 - Emergencies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... an emergency circumstance makes it necessary to take an action with significant environmental impact... CEQ's regulations limit such arrangements to actions necessary to control the immediate impacts of the... circumstance is defined as one involving an immediate or imminent danger to public health or safety. (b) Action...

  7. 76 FR 16391 - Call for Innovative National Environmental Policy Act (NEPA) Pilot Project Proposals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... COUNCIL ON ENVIRONMENTAL QUALITY Call for Innovative National Environmental Policy Act (NEPA) Pilot Project Proposals AGENCY: Council On Environmental Quality. ACTION: Notice of Availability, Call... the Council on Environmental Quality (CEQ) invites the public and federal agencies to nominate...

  8. 36 CFR 907.3 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... QUALITY § 907.3 Definitions. (a) CEQ Regulations means the regulations for implementing the procedural... which this part is a supplement. (b) The Act of October 27, 1972 or Act means the Pennsylvania Avenue... Plan means The Pennsylvania Avenue Plan—1974, prepared by the Pennsylvania Avenue Development...

  9. 14 CFR § 1216.300 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... policy are available on NASA's Public Portal at http://www.nasa.gov/agency/nepa/(under NEPA Process). ... implements NEPA, setting forth NASA's policies and procedures for the early integration of environmental considerations into planning and decision making. (b) Through this subpart, NASA adopts the CEQ regulations...

  10. 75 FR 48585 - Revision of Freedom of Information Act Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... Service Center and Reading Room; electronic FOIA requests; access to records published or released under... Disclosure Reading Room at: http://www.whitehouse.gov/administration/eop/ceq/foia/readingroom . In general... resources, particularly its Proactive Disclosure Reading Room, should be used to advance NEPA's goals of...

  11. 13 CFR 500.206 - Environmental requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... categorically excluded. The word “normally” is stressed; there may be individual cases in which specific factors..., or in other cases, potentially affect: (A) A floodplain; (B) A wetland; (C) Important farmlands, or..., consulting at his discretion with CEQ, shall examine carefully the basis on which supportive studies have...

  12. 7 CFR 2201.16 - Environmental requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... excluded. The word “normally” is stressed; there may be individual cases in which specific factors require..., or in other cases, potentially affect: (A) A floodplain; (B) A wetland; (C) Important farmlands, or... with CEQ, shall examine carefully the basis on which supportive studies have been conducted to assure...

  13. 7 CFR 2201.16 - Environmental requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... excluded. The word “normally” is stressed; there may be individual cases in which specific factors require..., or in other cases, potentially affect: (A) A floodplain; (B) A wetland; (C) Important farmlands, or... with CEQ, shall examine carefully the basis on which supportive studies have been conducted to assure...

  14. 13 CFR 500.206 - Environmental requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... categorically excluded. The word “normally” is stressed; there may be individual cases in which specific factors..., or in other cases, potentially affect: (A) A floodplain; (B) A wetland; (C) Important farmlands, or..., consulting at his discretion with CEQ, shall examine carefully the basis on which supportive studies have...

  15. 13 CFR 500.206 - Environmental requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... categorically excluded. The word “normally” is stressed; there may be individual cases in which specific factors..., or in other cases, potentially affect: (A) A floodplain; (B) A wetland; (C) Important farmlands, or..., consulting at his discretion with CEQ, shall examine carefully the basis on which supportive studies have...

  16. 40 CFR 1515.13 - Fees for categories of requesters.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Fees for categories of requesters. 1515.13 Section 1515.13 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF... further scholarly research, not an individual goal. (c) Representatives of the news media. CEQ shall...

  17. 40 CFR 1515.13 - Fees for categories of requesters.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Fees for categories of requesters. 1515.13 Section 1515.13 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF... further scholarly research, not an individual goal. (c) Representatives of the news media. CEQ shall...

  18. 40 CFR 1515.13 - Fees for categories of requesters.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Fees for categories of requesters. 1515.13 Section 1515.13 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF... further scholarly research, not an individual goal. (c) Representatives of the news media. CEQ shall...

  19. 40 CFR 1515.13 - Fees for categories of requesters.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Fees for categories of requesters. 1515.13 Section 1515.13 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF... further scholarly research, not an individual goal. (c) Representatives of the news media. CEQ shall...

  20. Understanding and Managing the Assessment Process

    Treesearch

    Gene Lessard; Scott Archer; John R. Probst; Sandra Clark

    1999-01-01

    Taking an ecological approach to management, or ecosystem management, is a developing approach for managing natural resources within the context of large geogaphic scales and over multiple time frames. Recently, the Council on Environmental Quality (CEQ) (IEMTF 1995) defined an ecosystem as "...an interconnected community of living things, including humans, and...

  1. 23 CFR 771.109 - Applicability and responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... responsibilities apply during the environmental review process: (1) The lead agencies are responsible for managing... shall serve as a joint lead agency with the Administration in accordance with 23 U.S.C. 139, and may...-recognized Indian tribal governmental units to serve as joint lead agencies in accordance with the CEQ...

  2. 23 CFR 771.109 - Applicability and responsibilities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... responsibilities apply during the environmental review process: (1) The lead agencies are responsible for managing... shall serve as a joint lead agency with the Administration in accordance with 23 U.S.C. 139, and may...-recognized Indian tribal governmental units to serve as joint lead agencies in accordance with the CEQ...

  3. 38 CFR 26.6 - Environmental documents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... significantly affecting the quality of the human environmental.” NEPA 102(2), 42 U.S.C. 4332(2) see CEQ... alter agency programs and which have a significant effect on the quality of the human environmental. (2...: (i) Probable significant degradation of historic or cultural resources, park lands, prime farmlands...

  4. 15 CFR 990.23 - Compliance with NEPA and the CEQ regulations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OIL POLLUTION...) The Draft Restoration Plan/EA must be made available for public review before concluding a FONSI or... analysis. (D) The time period for public review on the Draft Restoration Plan/EA must be consistent with...

  5. 15 CFR 990.23 - Compliance with NEPA and the CEQ regulations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OIL POLLUTION...) The Draft Restoration Plan/EA must be made available for public review before concluding a FONSI or... analysis. (D) The time period for public review on the Draft Restoration Plan/EA must be consistent with...

  6. 15 CFR 990.23 - Compliance with NEPA and the CEQ regulations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OIL POLLUTION...) The Draft Restoration Plan/EA must be made available for public review before concluding a FONSI or... analysis. (D) The time period for public review on the Draft Restoration Plan/EA must be consistent with...

  7. Accounting Students' Feedback on Feedback in Australian Universities: They're Less than Impressed

    ERIC Educational Resources Information Center

    Watty, Kim; de Lange, Paul; Carr, Rodney; O'Connell, Brendan; Howieson, Bryan; Jacobsen, Ben

    2013-01-01

    Undergraduate accounting students in Australian universities are dissatisfied with the feedback that they currently receive. Recent evidence from the Course Experience Questionnaire (CEQ, a national survey of Australian university graduates) suggests that the accounting discipline ranks poorly on assessment feedback when compared to other…

  8. 10 CFR 1021.101 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Policy. 1021.101 Section 1021.101 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES General § 1021.101 Policy. It is DOE's policy to follow the letter and spirit of NEPA; comply fully with the CEQ Regulations...

  9. 32 CFR 989.11 - Combining EIAP with other documentation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... documentation. (a) The EPF combines environmental analysis with other related documentation when practicable (40 CFR 1506.4) following the procedures prescribed by the CEQ regulations and this part. (b) The EPF must... the EIAP. Prior to making a decision to proceed, the EPF must analyze the environmental impacts that...

  10. 10 CFR 1021.101 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Policy. 1021.101 Section 1021.101 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NATIONAL ENVIRONMENTAL POLICY ACT IMPLEMENTING PROCEDURES General § 1021.101 Policy. It is DOE's policy to follow the letter and spirit of NEPA; comply fully with the CEQ Regulations...

  11. 40 CFR 1515.1 - FOIA procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Purpose § 1515.1 FOIA procedures. The Freedom of Information Act (5 U.S.C. 552), as amended, commonly known as... Section 552(b) of the Act. These procedures explain how the Council on Environmental Quality (CEQ)—one of...

  12. 40 CFR 1515.1 - FOIA procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Purpose § 1515.1 FOIA procedures. The Freedom of Information Act (5 U.S.C. 552), as amended, commonly known as... Section 552(b) of the Act. These procedures explain how the Council on Environmental Quality (CEQ)—one of...

  13. 40 CFR 1515.1 - FOIA procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Purpose § 1515.1 FOIA procedures. The Freedom of Information Act (5 U.S.C. 552), as amended, commonly known as... Section 552(b) of the Act. These procedures explain how the Council on Environmental Quality (CEQ)—one of...

  14. 40 CFR 1515.1 - FOIA procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY FREEDOM OF INFORMATION ACT PROCEDURES Purpose § 1515.1 FOIA procedures. The Freedom of Information Act (5 U.S.C. 552), as amended, commonly known as... Section 552(b) of the Act. These procedures explain how the Council on Environmental Quality (CEQ)—one of...

  15. 12 CFR 1815.113 - Public involvement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Public involvement. 1815.113 Section 1815.113...

  16. 12 CFR 1815.113 - Public involvement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Public involvement. 1815.113 Section 1815.113...

  17. 12 CFR 1815.113 - Public involvement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Public involvement. 1815.113 Section 1815.113...

  18. 12 CFR 1815.113 - Public involvement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Public involvement. 1815.113 Section 1815.113...

  19. 12 CFR 1815.113 - Public involvement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ENVIRONMENTAL QUALITY § 1815.113 Public involvement. All information collected by the Fund pursuant to this part shall be available to the public consistent with the CEQ regulations. Interested persons may obtain... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Public involvement. 1815.113 Section 1815.113...

  20. 75 FR 8046 - National Environmental Policy Act (NEPA) Draft Guidance, “NEPA Mitigation and Monitoring.”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... COUNCIL ON ENVIRONMENTAL QUALITY National Environmental Policy Act (NEPA) Draft Guidance, ``NEPA Mitigation and Monitoring.'' AGENCY: Council On Environmental Quality. ACTION: Notice of Availability, Draft... Quality (CEQ) announced four steps to modernize, reinvigorate, and ease the use and increase the...

  1. 15 CFR 990.23 - Compliance with NEPA and the CEQ regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ACT REGULATIONS NATURAL RESOURCE DAMAGE ASSESSMENTS Authorities § 990.23 Compliance with NEPA and the... will generally involve the need to develop restoration plans in the form of an Environmental Assessment...) Environmental Assessment. (i) Purpose. The purpose of an Environmental Assessment (EA) is to determine whether a...

  2. 32 CFR 651.14 - Integration with Army planning.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

  3. 32 CFR 651.14 - Integration with Army planning.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

  4. 32 CFR 651.14 - Integration with Army planning.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

  5. 32 CFR 651.14 - Integration with Army planning.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

  6. 32 CFR 651.14 - Integration with Army planning.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... be controversial. In most cases, local citizens and/or existing advisory groups should assist in... reduce or eliminate discussion of minor issues to help focus analyses. Such an approach will minimize... recommendations presented in the CEQ publication entitled “The National Environmental Policy Act: A Study of Its...

  7. A Systematic Analysis of Quality of Teaching Surveys

    ERIC Educational Resources Information Center

    Davies, Martin; Hirschberg, Joe; Lye, Jenny; Johnston, Carol

    2010-01-01

    All tertiary institutions in Australia use the same Course Experience Questionnaire (CEQ); however, for the internal evaluation of teaching they use their own surveys. This paper performs an analysis of the internal Quality of Teaching Surveys (QTS) used in Australian universities. We classify the questions within the QTS surveys. This…

  8. 14 CFR 1216.315 - Processing legislative environmental impact statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Processing legislative environmental impact... § 1216.315 Processing legislative environmental impact statements. (a) Preparation of a legislative environmental impact statement shall conform to the requirements of 40 CFR 1506.8 of the CEQ Regulations. The...

  9. ACHP | News | President Obama Launches America's Great Outdoors Initiative

    Science.gov Websites

    Initiative President Obama Launches America's Great Outdoors Initiative President Barack Obama signed a Presidential Memorandum April 16, 2010, establishing the America's Great Outdoors Initiative to promote and Environmental Quality (CEQ) to lead the initiative, in coordination with the Departments of Defense, Commerce

  10. Efficiency of Iranian Translation Syllabus at BA Level; Deficiency: A New Comprehensive Model

    ERIC Educational Resources Information Center

    Sohrabi, Sarah; Rahimi, Ramin; Arjmandi, Masoume

    2015-01-01

    This study aims at investigating the practicality of the current curriculum for translation studies at national level (Iranian curriculum). It is going to have a comprehensive idea of translation students and teachers (university lecturers) over the current translation syllabus at BA level in Iran. A researcher-made CEQ questionnaire (Curriculum…

  11. 36 CFR 1010.2 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Purpose. 1010.2 Section 1010.2 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.2 Purpose. The regulations in this part incorporate and supplement the Council on Environmental Quality's (CEQ) regulations at 40 CFR parts 1500 through 1508 for...

  12. Development and Preliminary Validation of the Collective Efficacy Questionnaire for Sports

    ERIC Educational Resources Information Center

    Short, Sandra E.; Sullivan, Philip; Feltz, Deborah L.

    2005-01-01

    This study presents the development and preliminary validation of the Collective Efficacy Questionnaire for Sports (CEQS). The study was conducted in 3 phases. In Phase 1, a 42-item questionnaire was developed and tested with 271 college-aged student-athletes. An exploratory factor analysis revealed 5 collective efficacy factors with 27 items…

  13. Flood Control, Roseau River, Roseau and Kittson Counties, Minnesota. Final Environmental Impact Statement. Supplement.

    DTIC Science & Technology

    1981-09-01

    business, and entrepreneur acquisition of presently marginal lands. The perceived result of withdrawal would be the shift of Roseau County from a com...impact statement (5S1) for this project we* plsed oa Eile witb the Council on Invironmenal Quality (CEQ) in April 1972. Because of incresing eaviromatal

  14. 76 FR 72218 - National Environmental Policy Act; NASA Routine Payloads on Expendable Launch Vehicles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ...; NASA Routine Payloads on Expendable Launch Vehicles AGENCY: National Aeronautics and Space... (CEQ) Regulations for Implementing the Procedural Provisions of NEPA (40 CFR parts 1500-1508), and NASA policy and procedures (14 CFR part 1216 subpart 1216.3), NASA has made a Finding of No Significant Impact...

  15. 21 CFR 25.41 - Findings of no significant impact.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Findings of no significant impact. 25.41 Section... ENVIRONMENTAL IMPACT CONSIDERATIONS Preparation of Environmental Documents § 25.41 Findings of no significant impact. (a) As defined by the CEQ regulations (40 CFR 1508.13), a FONSI is a document prepared by a...

  16. 32 CFR 651.11 - Environmental review categories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of human life or property in order to comply with this part or the CEQ regulations. However, the Army..., consistent with protecting human life, property, and national security. State call-ups of ARNG during a... impacts, such as those to promote national defense or security or to protect life or property, without the...

  17. 14 CFR 1216.308 - Preparation of draft statements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... submit the draft statement and any attachments to the Associate Administrator for Management for NASA review prior to any formal review outside NASA. This submission shall be accompanied by a list of Federal... parties (40 CFR 1506.6 of the CEQ Regulations) from whom comments should be requested. (b) After the NASA...

  18. Australian Higher Education and the Course Experience Questionnaire: Insights, Implications and Recommendations

    ERIC Educational Resources Information Center

    Talukdar, Joy; Aspland, Tania; Datta, Poulomee

    2013-01-01

    In recent years, Australian universities have come under pressure from Government and other stakeholder groups to demonstrate the quality of their activities. The Course Experience Questionnaire (CEQ) provides a valuable source of data about student satisfaction regarding the courses that they study at Australian universities. It provides a body…

  19. 75 FR 62418 - Notice of Intent To Conduct a Review of Categorical Exclusions for Outer Continental Shelf Decisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-08

    ... Shelf Oil and Gas Exploration and Development'' (August 16, 2010). Furthermore, this notice provides the... amended, established a national policy to protect the environment and also established the President's... procedures to implement NEPA, to consult with CEQ during their development, to provide an opportunity for...

  20. 3 CFR 13653 - Executive Order 13653 of November 1, 2013. Preparing the United States for the Impacts of Climate...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Council on Environmental Quality (CEQ), the Office of Science and Technology Policy (OSTP), and the... National Science and Technology Council and those that support the implementation of Presidential Policy... integration of climate science in policies and planning of government agencies and the private sector...

  1. Exploring the Use of Best-Worst Scaling to Elicit Course Experience Questionnaire Responses

    ERIC Educational Resources Information Center

    Huybers, Twan

    2017-01-01

    Students are an important stakeholder group in the context of quality assurance in higher education. From their perspective as learners, students' views on educational experiences are increasingly used as an indicator of educational quality. The Course Experience Questionnaire (CEQ) is a widely used quantitative tool to gauge students' perceptions…

  2. 78 FR 16483 - Notice of Availability of the Draft Uranium Leasing Program Programmatic Environmental Impact...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ...The U.S. Department of Energy (DOE) announces the availability of the Draft Uranium Leasing Program Programmatic Environmental Impact Statement (Draft ULP PEIS, DOE/EIS-0472D), for public comment. DOE is also announcing the dates, times, and locations for public hearings to receive comments on the Draft ULP PEIS. DOE has prepared the Draft ULP PEIS pursuant to the National Environmental Policy Act of 1969 (NEPA), the Council on Environmental Quality's (CEQ's) NEPA regulations (40 CFR parts 1500-1508), and DOE's NEPA implementing procedures (10 CFR part 1021) to analyze the reasonably foreseeable potential environmental impacts, including the site-specific impacts, of the range of reasonable alternatives for the management of the ULP. DOE's ULP administers 31 tracts of land covering an aggregate of approximately 25,000 acres (10,000 ha) in Mesa, Montrose, and San Miguel Counties in western Colorado for exploration, mine development, operations, and reclamation of uranium mines. The cooperating agencies on this ULP PEIS are the: U.S. Department of the Interior (DOI), Bureau of Land Management (BLM); U.S. Environmental Protection Agency (EPA); Colorado Department of Transportation; Colorado Division of Reclamation, Mining, and Safety; Colorado Parks and Wildlife ; Mesa County Commission; Montrose County Commission; San Juan County Commission; San Miguel County Board of Commissioners; Pueblo of Acoma Tribe; Pueblo de Cochiti Tribe; Pueblo de Isleta Tribe; Navajo Nation; and Southern Ute Indian Tribe.

  3. 22 CFR 161.9 - Specific steps in the Department's NEPA process.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... cooperation with the Office of Environment and Health, initiate steps to prepare an environmental impact... proposed action may have a significant impact on the human environment the necessary revision in the... Environment and Health, prepare a “Finding of no significant impact” (see §§ 1501.4 and 1508.13 of the CEQ...

  4. Environmental Assessment for Construction of the Distributed Common Ground Station (DCGS) at Langley Air Force Base, Virginia

    DTIC Science & Technology

    2007-03-01

    located in the north-central part of the base and includes the areas occupied by the golf course clubhouse , maintenance building, and the driving range...foreseeable future actions regardless of what agency or person undertakes such other actions” (40 CFR 1508.7). Recent CEQ guidance in Considering

  5. 77 FR 38882 - Notice of Availability of a Draft Environmental Impact Statement, for the Chicago, IL to St...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... INFORMATION CONTACT: Andrea E. Martin, Environmental Protection Specialist, Office of Railroad Policy and... Environmental Policy Act of 1969 (NEPA) (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ... viewing at the following locations along the Corridor: Hayner Library, 326 Belle Street, Alton, IL 62002...

  6. The Adaptation and Validation of the CEQ and the R-SPQ-2F to the Japanese Tertiary Environment

    ERIC Educational Resources Information Center

    Fryer, Luke K.; Ginns, Paul; Walker, Richard A.; Nakao, Kaori

    2012-01-01

    Background: Student learning theory (SLT) has established associations between students' approaches to learning and their perceptions of the learning environment. SLT may provide a useful framework for researching student learning within the Japanese tertiary sector. Aims: The study aims to explore and validate the Course Experience Questionnaire…

  7. A Quantitative Approach to Assessment of Work-Based Learning Outcomes: An Urban Planning Application

    ERIC Educational Resources Information Center

    Freestone, Robert; Williams, Peter; Thompson, Susan; Trembath, Kerry

    2007-01-01

    Assessing student perceptions and opinions of their university education is now standard in quality assurance processes for learning and teaching. In Australia, the Course Experience Questionnaire (CEQ) has been institutionalised as a national survey of graduand opinion and is used as the key indicator of tertiary teaching quality. A little-used…

  8. 40 CFR 1515.5 - Making a Freedom of Information Act request.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Reading Room where CEQ makes available records pertaining to matters within the scope of 5 U.S.C. 552(a)(2... requesters to review documents currently available from the Center's Online Reading Room before submitting a... scope of their request in order to qualify for faster processing. (4) The Council will make a reasonable...

  9. 76 FR 51391 - Commercial Wind Lease Issuance and Site Characterization Activities on the Atlantic Outer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... Environmental Assessment. SUMMARY: This notice is being published as an initial step for the purpose of... areas, in accordance with the DOI and the Council on Environmental Quality (CEQ) regulations implementing the provisions of the National Environmental Policy Act (NEPA) of 1969 as amended (42 U.S.C. 4321...

  10. 15 CFR 990.23 - Compliance with NEPA and the CEQ regulations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., federal trustees must issue a Finding of No Significant Impact (FONSI) as part of the restoration plans... Plan/EA and FONSI. (F) The means by which a federal trustee requests, considers, and responds to public comments on the Draft Restoration Plan/EA and FONSI must also be consistent with the federal agency's NEPA...

  11. International Student Experience: What It Is, What It Means and Why It Matters

    ERIC Educational Resources Information Center

    Thakur, Marian; Hourigan, Clare

    2007-01-01

    The Course Experience Questionnaire (CEQ) was administered to recent university graduates by Graduate Careers Australia (GCA) in order to obtain feedback about their perceptions of their course. Students were asked to rate the extent to which they agree with a series of 49 statements covering issues surrounding the education and support services…

  12. Turning stumbling blocks into stepping stones in the analysis of cumulative impacts

    Treesearch

    Leslie M. Reid

    2004-01-01

    Federal and state legislation, such as the National Environmental Policy Act and the California Environmental Quality Act, require that responsible agency staff consider the cumulative impacts of proposed activities before permits are issued for certain kinds of public or private projects. The Council on Environmental Quality (CEQ 1997) defined a cumulative impact as...

  13. 28 CFR Appendix C to Part 61 - Immigration and Naturalization Service Procedures Relating to the Implementation of the National...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INS facility which would have a significant impact upon the environment. (b) Construction of a new... have a significant impact upon the environment. (Reference: § 1507.3(b)(2)(i)—CEQ Regulations.) 10... significantly impact upon the environment. (b) Increase or decrease in population of a facility within its...

  14. Final Environmental Assessment: Demolition of Barracks (Building T-2) at Ipswich Antenna Test Facility

    DTIC Science & Technology

    2011-12-01

    EIAP), managed the preparation and was the primary author of this environmental assessment. QAULITY ASSURANCE LEADER Cravedi, Gregory. 66 ABG/CE...BMP Best Management Practice CEQ Council on Environmental Quality CERCLA Comprehensive Environmental Response, Compensation, and Liability Act...Assessment EMCS Energy Management Control System ESC Electronic Systems Center FEMA Federal Emergency Management Agency FIRM Federal

  15. 75 FR 5290 - Notice of the Record of Decision for the United States Marine Corps Grow the Force at Marine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ...) of 1969, 42 United States Code (U.S.C.) Section 4332(2)(c), the regulations of the Council on Environmental Quality (CEQ) for Implementing the Procedural Provisions of NEPA (40 Code of Federal Regulations... infrastructure construction (e.g. buildings, roads, utility lines); (2) demolition and/or upgrades to existing...

  16. Environmental impacts of dispersed development from federal infrastructure projects.

    PubMed

    Southerland, Mark T

    2004-06-01

    Dispersed development, also referred to as urban growth or sprawl, is a pattern of low-density development spread over previously rural landscapes. Such growth can result in adverse impacts to air quality, water quality, human health, aquatic and terrestrial ecosystems, agricultural land, military training areas, water supply and wastewater treatment, recreational resources, viewscapes, and cultural resources. The U.S. Environmental Protection Agency (U.S. EPA) is charged with protecting public health and the environment, which includes consideration of impacts from dispersed development. Specifically, because federal infrastructure projects can affect the progress of dispersed development, the secondary impacts resulting from it must be assessed in documents prepared under the National Environmental Policy Act (NEPA). The Council on Environmental Quality (CEQ) has oversight for NEPA and Section 309 of the Clean Air Act requires that U.S. EPA review and comment on federal agency NEPA documents. The adverse effects of dispersed development can be induced by federal infrastructure projects including transportation, built infrastructure, modifications in natural infrastructure, public land conversion and redevelopment of properties, construction of federal facilities, and large traffic or major growth generation developments requiring federal permits. This paper presents an approach that U.S. EPA reviewers and NEPA practitioners can use to provide accurate, realistic, and consistent analysis of secondary impacts of dispersed development resulting from federal infrastructure projects. It also presents 24 measures that can be used to mitigate adverse impacts from dispersed development by modifying project location and design, participating in preservation or restoration activities, or informing and supporting local communities in planning.

  17. Environmental Assessment for Housing Demolition, Construction, Renovation, and Leasing Bethel Manor, Lighter-Than-Air, and Heavier-Than-Air Military Family Housing Areas

    DTIC Science & Technology

    2006-08-01

    storm water system or connections would be designed and constructed to comply with current VDES regulations. The No Action discussion for a storm...3-11 3.5.6 Transportation System .............................................................................. 3...Waste Systems of Virginia CAA Clean Air Act CDP Community Development Plan CEQ Council on Environmental Quality CERCLA Comprehensive Environmental

  18. Environmental Assessment: Demolish 934 of Grand Forks Air Force Base

    DTIC Science & Technology

    2006-03-01

    adverse human health or environmental effects of their programs, policies , and activities on minority and low-income populations. There is no minority...AF Form 813 fulfill the requirements of the National Environmental Policy Act (NEPA), the Council of Environmental Quality (CEQ) regulations...Designation: Final Environmental Assessment (EA) Abstract: This EA has been prepared in accordance with the National Environmental Policy Act, and

  19. Impact of Faculty Development Workshops in Student-Centered Teaching Methodologies on Faculty Members' Teaching and Their Students' Perceptions.

    PubMed

    Tricio, Jorge A; Montt, Juan E; Ormeño, Andrea P; Del Real, Alberto J; Naranjo, Claudia A

    2017-06-01

    The aim of this study was to assess, after one year, the impact of faculty development in teaching and learning skills focused on a learner-centered approach on faculty members' perceptions of and approaches to teaching and on their students' learning experiences and approaches. Before training (2014), all 176 faculty members at a dental school in Chile were invited to complete the Approaches to Teaching Inventory (ATI) to assess their teaching approaches (student- vs. teacher-focused). In 2015, all 496 students were invited to complete the Study Process Questionnaire (R-SPQ-2F) to assess their learning approaches (deep or surface) and the Course Experience Questionnaire (CEQ) to measure their teaching quality perceptions. Subsequently, faculty development workshops on student-centered teaching methodologies were delivered, followed by peer observation. In March 2016, all 176 faculty members and 491 students were invited to complete a second ATI (faculty) and R-SPQ-2 and CEQ (students). Before (2014) and after (2016) the training, 114 (65%) and 116 (66%) faculty members completed the ATI, respectively, and 89 (49%) of the then-181 faculty members completed the perceptions of skills development questionnaire in September 2016. In 2015, 373 students (75%) completed the R-SPQ-2F and CEQ; 412 (83%) completed both questionnaires in 2016. In 2014, the faculty results showed that student-focused teaching was significantly higher in preclinical and clinical courses than in the basic sciences. In 2016, teacher-focused teaching fell significantly; basic science teaching improved the most. Students in both the 2015 and 2016 cohorts had lower mean scores for deep learning approaches from year 1 on, while they increased their scores for surface learning. The students' perceptions of faculty members' good teaching, appropriate assessment, clear goals, and e-learning improved significantly, but perception of appropriate workload did not. Teaching and learning skills development produced significant gains in student-centered teaching for these faculty members and in some students' perceptions of teaching quality. However, student workload needs to be considered to support deep learning.

  20. Full GHG balance of a drained fen peatland cropped to spring barley and reed canary grass using comparative assessment of CO2 fluxes.

    PubMed

    Karki, Sandhya; Elsgaard, Lars; Kandel, Tanka P; Lærke, Poul Erik

    2015-03-01

    Empirical greenhouse gas (GHG) flux estimates from diverse peatlands are required in order to derive emission factors for managed peatlands. This study on a drained fen peatland quantified the annual GHG balance (Carbon dioxide (CO2), nitrous oxide (N2O), methane (CH4), and C exported in crop yield) from spring barley (SB) and reed canary grass (RCG) using static opaque chambers for GHG flux measurements and biomass yield for indirectly estimating gross primary production (GPP). Estimates of ecosystem respiration (ER) and GPP were compared with more advanced but costly and labor-intensive dynamic chamber studies. Annual GHG balance for the two cropping systems was 4.0 ± 0.7 and 8.1 ± 0.2 Mg CO2-Ceq ha(-1) from SB and RCG, respectively (mean ± standard error, n = 3). Annual CH4 emissions were negligible (<0.006 Mg CO2-Ceq ha(-1)), and N2O emissions contributed only 4-13 % of the full GHG balance (0.5 and 0.3 Mg CO2-Ceq ha(-1) for SB and RCG, respectively). The statistical significance of low CH4 and N2O fluxes was evaluated by a simulation procedure which showed that most of CH4 fluxes were within the range that could arise from random variation associated with actual zero-flux situations. ER measured by static chamber and dynamic chamber methods was similar, particularly when using nonlinear regression techniques for flux calculations. A comparison of GPP derived from aboveground biomass and from measuring net ecosystem exchange (NEE) showed that GPP estimation from biomass might be useful, or serve as validation, for more advanced flux measurement methods. In conclusion, combining static opaque chambers for measuring ER of CO2 and CH4 and N2O fluxes with biomass yield for GPP estimation worked well in the drained fen peatland cropped to SB and RCG and presented a valid alternative to estimating the full GHG balance by dynamic chambers.

  1. Environmental Impact Statement for Realignment of Beale Air Force Base, California

    DTIC Science & Technology

    1990-07-01

    California Department of Fish and Game CEQ Council of Environmental Quality CERCLA Comprehensive Environmental Response, Compensation, and Liability Act...housing can be developed on government-owned land only with special permission of the Secretary of the Air Force, permission that is infrequently...was not measured in other drainage systems at Beale AFB; however, it can be assumed to have similar characteristics to those reported for Hutchinson

  2. 58th SOW Low-Dust Helicopter Landing Zone Final Environmental Assessment

    DTIC Science & Technology

    2012-11-01

    Effects AQCR Air Quality Control Region BASH Bird/wildlife-Aircraft Strike Hazard CEQ Council on Environmental Quality CFR Code of Federal Regulations...force would continue to be applied to minimize risks to aircrews and the general population. No unacceptable hazards to military personnel, the public...and Final EA As a result of comments received on the Draft EA, Section 3.1.2, Global Climate Change, and Hazardous and Toxic Materials and Waste

  3. Termination of Lease and the Transfer of Property Back to the Landowner for the Matagorda, Texas Tethered Aerostat Radar System (TARS) Site

    DTIC Science & Technology

    2010-01-01

    Above-ground Storage Tank CAA Clean Air Act CEQ Council on Environmental Quality CERCLA Comprehensive Environmental Response...on Environmental Quality TDLR Texas Department of Licensing and Regulation THC Texas Historical Commission TPWD Texas Parks and... Storage Tank FINDING OF NO SIGNIFICANT IMPACT 1.0 NAME OF THE PROPOSED ACTION Environmental Assessment (EA) for the proposed action to terminate the

  4. Environmental Assessment Addressing the Expansion of Sortie-Operations at Moody Air Force Base, Georgia

    DTIC Science & Technology

    2012-08-01

    include the tactical delivery of air-to-ground munitions, laser designation of targets from ground and airborne platforms, and threat evasion. These...world events, which include the tactical delivery of air-to-ground munitions, laser designation of targets from ground and airborne platforms, and...Closure CAA Clean Air Act CAU Classic Associate Unit CEQ Council on Environmental Quality CFR Code of Federal Regulations CO carbon monoxide

  5. Cave Buttes Dam Master Plan, Phoenix, Arizona and Vicinity (Including New River).

    DTIC Science & Technology

    1982-03-01

    Mar. 1975 Arizona, Hydrology, Part 1 3 New River and Phoenix City Streams, Mar. 1976 July 1977 Arizona, Design Memorandum No. 3, (SPD App) General ...with Maricopa County, Arizona CEQ) 3 New River and Phoenix City Streams, Arizona, Design Memorandum No. 3, General Design Memorandum--Phase II, Project...Hydrology Part 2 3 New River and Phoenix City Streams, Arizona, Design Memorandum No. 3, General Design Memorandum--Phase II, Project Design Part 3

  6. Effect of stabilizer on the maximum degree and extent of supersaturation and oral absorption of tacrolimus made by ultra-rapid freezing.

    PubMed

    Overhoff, Kirk A; McConville, Jason T; Yang, Wei; Johnston, Keith P; Peters, Jay I; Williams, Robert O

    2008-01-01

    Solid dispersions containing various stabilizers and tacrolimus (TAC) prepared by an Ultra-rapid Freezing (URF) process were investigated to determine the effect on their ability to form supersaturated solutions in aqueous media and on enhancing transport across biological membranes. The stabilizers included poly(vinyl alcohol; PVA), poloxamer 407 (P407), and sodium dodecyl sulfate (SDS). In vivo absorption enhancement in rats was also investigated. Dissolution studies were conducted at supersaturated conditions in both acidic media for 24 h and at delayed release (enteric) conditions to simulate intestinal transit. The rank order of C/Ceq(max) in the dissolution studies at acidic conditions was URF-P407 > URF-SDS > Prograf (PRO) > URF-PVA:P407. For C/Ceq(max) under enteric conditions, the order was URF-SDS > PRO > URF-PVA:P407 > URF-P407, and for the extent of supersaturation (AUC) in acidic and pH shift conditions it was URF-SDS>PRO>URF-PVA:P407>URF-P407. The pharmacokinetic data suggests URF-P407 had the greatest absorption having higher C (max) with a 1.5-fold increase in AUC compared to PRO. All URF compositions had a shorter T (max) compared to PRO. The nanostructured powders containing various stabilizing polymers formed by the URF process offer enhanced supersaturation characteristics leading to increased oral absorption of TAC.

  7. Final Environmental Assessment Addressing 21st Explosive Ordinance Disposal Weapons of Mass Destruction Facilities Demolition and Expansion at Kirtland Air Force Base, New Mexico

    DTIC Science & Technology

    2011-07-01

    KIRTLAND AIR FORCE BASE, NEW MEXICO JULY 2011 Report Documentation Page Form ApprovedOMB No. 0704...Facilities Demolition and Expansion at Kirtland Air Force Base, New Mexico 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...EXPANSION KIRTLAND AIR FORCE BASE, NEW MEXICO Pursuant to the Council on Environmental Quality (CEQ) regulations for implementing procedural

  8. Multi-Variable Analysis and Design Techniques.

    DTIC Science & Technology

    1981-09-01

    factors through ri. Fact: - is a partial order on E(X) and induces a lattice structure. Namely for any ri,0, [(X) there exists I := YlAtl with the...U- (0.- -qi. U C 0 ro.* qcd .-O ’ 3 . mC V03 -- Dh-J CEQ-UO C O) C C 00 0 m U CO )CQL IG L ?( (5 Li C -0 -0Z0M0-U010 0 4)1- EC -0 - 0 C:) -D >Z 1 J a

  9. The EIS (Environmental Impact Statement) Process in Relation to the Proposed Naval Task Force at Everett, Washington,

    DTIC Science & Technology

    1983-01-01

    which involves unresolved conflicts e. V.V..4 President OMB Cirua * NEPA of 1969 (42 U.S.C. 4321) CEQ/EIS Guidelines 40 CFR 1500-1508 . 7 Excuiv Ordc...Classification and Declassification Committee under the EPA Administrator reviews and reco- 4 " mmends to the Administrator actions where conflicts arise out of...Ordinaces - 1. Permits 2. Regulations 3. Specific Enviromental Parameters 4. Zoning Regulations *!’- I. EIS statements for the Puget Sound Project

  10. Assessment of motivation to control alcohol use: The motivational thought frequency and state motivation scales for alcohol control.

    PubMed

    Robinson, Nicole; Kavanagh, David; Connor, Jason; May, Jon; Andrade, Jackie

    2016-08-01

    The Elaborated Intrusion Theory of Desire holds that desires for functional and dysfunctional goals share a common form. Both are embodied cognitive events, characterised by affective intensity and frequency. Accordingly, we developed scales to measure motivational cognitions for functional goals (Motivational Thought Frequency, MTF; State Motivation, SM), based on the existing Craving Experience Questionnaire (CEQ). When applied to increasing exercise, MTF and SM showed the same three-factor structure as the CEQ (Intensity, Imagery, Availability). The current study tested the internal structure and concurrent validity of the MTF and SM Scales when applied to control of alcohol consumption (MTF-A; SM-A). Participants (N=417) were adult tertiary students, staff or community members who had recently engaged in high-risk drinking or were currently trying to control alcohol consumption. They completed an online survey comprising the MTF-A, SM-A, Alcohol Use Disorders Identification Test (AUDIT), Readiness to Change Questionnaire (RCQ) and demographics. Confirmatory Factor Analysis gave acceptable fit for the MTF-A, but required the loss of one SM-A item, and was improved by intercorrelations of error terms. Higher scores were associated with more severe problems on the AUDIT and with higher Contemplation and Action scores on the RCQ. The MTF-A and SM-A show potential as measures of motivation to control drinking. Future research will examine their predictive validity and sensitivity to change. The scales' application to both increasing functional and decreasing dysfunctional behaviours is consistent with EI Theory's contention that both goal types operate in similar ways. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Big George to Carter Mountain 115-kV transmission line project, Park and Hot Springs Counties, Wyoming. Environmental Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-02-01

    The Western Area Power Administration (Western) is proposing to rebuild, operate, and maintain a 115-kilovolt (kV) transmission line between the Big George and Carter Mountain Substations in northwest Wyoming (Park and Hot Springs Counties). This environmental assessment (EA) was prepared in compliance with the National Environmental Policy Act (NEPA) and the regulations of the Council on Environmental Quality (CEQ) and the Department of Energy (DOE). The existing Big George to Carter Mountain 69-kV transmission line was constructed in 1941 by the US Department of Interior, Bureau of Reclamation, with 1/0 copper conductor on wood-pole H-frame structures without an overhead groundmore » wire. The line should be replaced because of the deteriorated condition of the wood-pole H-frame structures. Because the line lacks an overhead ground wire, it is subject to numerous outages caused by lightning. The line will be 54 years old in 1995, which is the target date for line replacement. The normal service life of a wood-pole line is 45 years. Under the No Action Alternative, no new transmission lines would be built in the project area. The existing 69-kV transmission line would continue to operate with routine maintenance, with no provisions made for replacement.« less

  12. Dopaminergic genetic variation moderates the effect of nicotine on cigarette reward.

    PubMed

    Harrell, Paul T; Lin, Hui-Yi; Park, Jong Y; Blank, Melissa D; Drobes, David J; Evans, David E

    2016-01-01

    Cigarette smoking is influenced by nicotine’s effects on dopaminergic activity in the mesocorticolimbic pathway. This activity appears to be moderated by genetic variation, specifically a variable number tandem repeat (VNTR) polymorphism in the third exon of the dopamine receptor gene (DRD4). We examined whether this polymorphism along with three DRD4 single-nucleotide polymorphisms (SNPs: rs936460, rs936461, and rs12280580) moderate the influence of nicotine on subjective responses to cigarettes. White, non-Hispanic smokers (n = 96, cigarettes/day ≥15) attended two double-blind, counterbalanced experimental sessions, each preceded by overnight smoking abstinence. Participants smoked four nicotine (8.9 mg) or placebo (1.0 mg) cigarettes per session, with each cigarette followed by completion of the modified Cigarette Evaluation Questionnaire (mCEQ). We examined the mCEQ composite score via 2 × 2 × 4 ANOVAs with genotype (major homozygotes versus minor carriers) as the between-subject factor and nicotine content and smoking bout as within-subject factors. Although DRD4 VNTR variation did not moderate overall nicotine response, there was a moderation of nicotine response over successive cigarettes. Smokers with fewer than seven repeats for the DRD4 VNTR reported markedly reduced craving, increased satisfaction, and a greater calming effect in response to earlier smoked nicotine cigarettes, whereas those with seven or more repeats did not. In addition, minor carriers for all three DRD4 SNPs displayed blunted overall response to nicotine. These findings provide support for DRD4 variation as an informative predictor of subjective responses to nicotine. We discuss how these data may lead to improved tailoring of smoking cessation pharmacotherapies.

  13. A Preliminary Investigation on Smokeless Tobacco Use and Its Cognitive Effects Among Athletes

    PubMed Central

    Zandonai, Thomas; Chiamulera, Cristiano; Mancabelli, Alberto; Falconieri, Danilo; Diana, Marco

    2018-01-01

    Introduction: Among athletes, an increasing use of nicotine via smokeless tobacco has been reported. However, there are currently unanswered questions about whether the use by athletes is due to nicotine’s addictive properties and/or to benefits in physical and cognitive performance (e.g., decision-making). In this original article we reported about, (i) snus-induced reinforcing effects among snus-user athletes (Survey) and (ii) the effects of snus on the Iowa Gambling Task (IGT) in snus-user skiers (Experimental study). IGT is an experimental neuropsychological task that has been previously used on athletes and addicts to test decision-making. Methods: Survey: data were collected with the modified Cigarette Evaluation Questionnaire (mCEQ) that was administered to 61 winter sport athlete snus-users in Northern Italy. Experimental study: IGT data included: amount of money earned, number of choices from advantageous and disadvantageous decks and overall net score. Eighteen male snus-users were tested under satiety or after 12-h abstinence conditions according to a crossover design. Results: Survey: the comparison between occasional vs. regular snus-users showed a statistically significant difference in satisfaction (P = 0.0088), calm (P = 0.0252), and enjoyment (P = 0.0001) mCEQ items suggesting a snus intake/effect relationship. Experimental study: significantly higher IGT net scores were found during the first 20 choice cards after abstinence vs. satiety conditions (P = 0.0024). Conclusion: In the Survey, regular snus use induces greater satisfaction and psychological reward than occasional use. In the Experimental study, snus intake might produce an early and transient cognitive improvement on IGT in abstinent snus-users, presumably acting as a withdrawal relief. PMID:29593541

  14. Feasibility of a cognitive strategy training intervention for people with Parkinson's disease.

    PubMed

    Foster, Erin R; Spence, Daniel; Toglia, Joan

    2018-05-01

    To investigate the feasibility of a novel client-centered cognitive strategy training intervention for people with Parkinson's disease (PD). This was a case series of seven people with PD without dementia but with subjective cognitive decline. The intervention involved ≥5 treatment sessions at the participant's home. Participant acceptance and engagement were assessed by the Credibility/Expectancy Questionnaire (CEQ), Client Satisfaction Questionnaire (CSQ), enjoyment and effort ratings, and homework completion. Logistical information was tracked, and the Canadian Occupational Performance Measure (COPM) was an exploratory outcome measure. Data analysis was descriptive. CEQ scores were positive and increased over time. CSQ scores were high (M = 30.8, SD = 0.75), with all participants rating all items positively. Almost all (95%) effort and enjoyment ratings were ≥3 (Much), and homework completion rates averaged 84% (SD = 18). Intervention duration was 6-15 weeks (M = 9.2, SD = 2.8), with treatment sessions averaging 1.7 h (SD = 0.5). Group and most individual COPM ratings improved ≥2 points. These findings support the feasibility of the intervention for people with PD. It was acceptable, engaging, and promising in terms of its effect on self-identified functional cognitive problems. Implications for Rehabilitation People with Parkinson's disease (PD) without dementia can experience cognitive decline that negatively impacts function and quality of life. Strategy-based interventions that explicitly train for transfer may mitigate the negative functional consequences of cognitive decline in this population. We developed a client-centered cognitive strategy training intervention for people with PD. This small case series supports its feasibility, indicating that it is acceptable and engaging for people with PD and promising in terms of its effect on self-identified functional cognitive problems.

  15. Robot-assisted task-oriented upper extremity skill training in cervical spinal cord injury: a feasibility study.

    PubMed

    Vanmulken, D A M M; Spooren, A I F; Bongers, H M H; Seelen, H A M

    2015-07-01

    Prospective multiple case study. To test (1) the feasibility of haptic robot technology (Haptic Master (HM)) use to improve arm-hand function (AHF) and arm-hand skill performance (AHSP) in persons with a cervical spinal cord injury (C-SCI), (2) inventory participants' motivation and expectation to work with the robot technology used and (3) to descriptively report the results in individual cases. Rehabilitation Centre. Five C-SCI patients were trained for 6 weeks, 3 days per week, 60 min per day. Therapists filled out the Usefulness, Satisfaction and Ease-of-use questionnaire (USE). The Intrinsic Motivational Inventory (IMI) and credibility and expectancy questionnaire (CEQ) were filled out by participants. Performance at activity level was gauged using the Van Lieshout test for AHF in Tetraplegia and the Spinal Cord Independence Measure. Function level was gauged using muscle strength testing and the International Classification for Surgery of the Hand in Tetraplegia. As to the feasibility of the application of haptic robot technology, the mean USE score was 65%. Mean IMI and CEQ results were 67% and 60%, respectively. Participants were motivated to train with the HM. All participants rated credibility higher than expectations regarding the improvement. In the current patients, little progress was demonstrated at the International Classification of Functioning, Disability and Health function and the activity level. It is feasible to train C-SCI persons with the HM. Therapists report that working with the HM is easy to learn and easy to perform. Usability of the HM may be improved. Further research is needed to assess in which group of C-SCI and at which stage of rehabilitation HM training may be most beneficial.

  16. 77 FR 74665 - Notice of Intent To Prepare an Environmental Impact Statement, Public Scoping Meeting, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ...The Centers for Disease Control and Prevention (CDC) within the Department of Health and Human Services (HHS) announces its intent to prepare an Environmental Impact Statement (EIS) for the proposed 2015-2025 Facilities Master Plan for HHS/CDC's Edward R. Roybal Campus located at 1600 Clifton Road NE., in Atlanta, Georgia. This announcement follows the requirements of the National Environmental Policy Act of 1969 (NEPA) as implemented by the Council on Environmental Quality (CEQ) Regulations (40 CFR Part 1500-1508); and, the Department of Health and Human Services (HHS) General Administration Manual Part 30 Environmental Procedures, dated February 25, 2000.

  17. Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    2011-01-01

    Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723).DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 etmore » seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations:Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho;Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.« less

  18. Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723). DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321more » et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations: Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho; Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.« less

  19. Estimating the gas transfer velocity: a prerequisite for more accurate and higher resolution GHG fluxes (lower Aare River, Switzerland)

    NASA Astrophysics Data System (ADS)

    Sollberger, S.; Perez, K.; Schubert, C. J.; Eugster, W.; Wehrli, B.; Del Sontro, T.

    2013-12-01

    Currently, carbon dioxide (CO2) and methane (CH4) emissions from lakes, reservoirs and rivers are readily investigated due to the global warming potential of those gases and the role these inland waters play in the carbon cycle. However, there is a lack of high spatiotemporally-resolved emission estimates, and how to accurately assess the gas transfer velocity (K) remains controversial. In anthropogenically-impacted systems where run-of-river reservoirs disrupt the flow of sediments by increasing the erosion and load accumulation patterns, the resulting production of carbonic greenhouse gases (GH-C) is likely to be enhanced. The GH-C flux is thus counteracting the terrestrial carbon sink in these environments that act as net carbon emitters. The aim of this project was to determine the GH-C emissions from a medium-sized river heavily impacted by several impoundments and channelization through a densely-populated region of Switzerland. Estimating gas emission from rivers is not trivial and recently several models have been put forth to do so; therefore a second goal of this project was to compare the river emission models available with direct measurements. Finally, we further validated the modeled fluxes by using a combined approach with water sampling, chamber measurements, and highly temporal GH-C monitoring using an equilibrator. We conducted monthly surveys along the 120 km of the lower Aare River where we sampled for dissolved CH4 (';manual' sampling) at a 5-km sampling resolution, and measured gas emissions directly with chambers over a 35 km section. We calculated fluxes (F) via the boundary layer equation (F=K×(Cw-Ceq)) that uses the water-air GH-C concentration (C) gradient (Cw-Ceq) and K, which is the most sensitive parameter. K was estimated using 11 different models found in the literature with varying dependencies on: river hydrology (n=7), wind (2), heat exchange (1), and river width (1). We found that chamber fluxes were always higher than boundary layer results based on ';manual' sampling. The closest flux approximation was obtained using the river width-dependent model. The higher fluxes obtained by the chambers could partially be explained by an enhanced turbulence created in the chambers themselves, especially because the ratio between the water surface area and chamber volume was rather small. The high resolution combined sampling approach helped constrain K and determine which river model best fits Aare River emissions. This experimental setup ultimately allows us to (1) define the dependence of K, (2) measure CH4 and CO2 fluxes from the main river and different tributaries more accurately, (3) estimate more spatially-resolved fluxes via either models or water sampling and the newly found K, and (4) determine one of the fates of carbon in the Aare River.

  20. Minnesota River at Chaska, Minnesota, Flood Control. Final Environmental Impact Statement.

    DTIC Science & Technology

    1975-07-01

    and 10 acres of floodplain wetland interspersed with bottouland trees.J IAN is03 ~ UNCLASSIFIED >ZD D W 3 W ~ a " r I n w a s s O ft t f r a S &c u m A...T C L M P IC A? I O W O f! ThU S C A B S ( M an WS. S w r Drainage of about 30 acres ot wetland WOU14 be cmpeted by the Last Claek bypasschanne. ada...Final Statement to CEQ: ii "WJI RO:N:TAL I.WACT STATMM1N2 FLOOD JOXTPOLFO AT M IIIEZOTA. 14INESOTA RIVEP TAbLk OF C::,Er SUMMAY ENVI ROU *rA. 0-AX: I

  1. An Empirical Comparison of the EQ-5D-5L, DEMQOL-U and DEMQOL-Proxy-U in a Post-Hospitalisation Population of Frail Older People Living in Residential Aged Care.

    PubMed

    Ratcliffe, Julie; Flint, Thomas; Easton, Tiffany; Killington, Maggie; Cameron, Ian; Davies, Owen; Whitehead, Craig; Kurrle, Susan; Miller, Michelle; Liu, Enwu; Crotty, Maria

    2017-06-01

    To empirically compare the measurement properties of the DEMQOL-U and DEMQOL-Proxy-U instruments to the EQ-5D-5L and its proxy version (CEQ-5D-5L) in a population of frail older people living in residential aged care in the post-hospitalisation period following a hip fracture. A battery of instruments to measure health-related quality of life (HRQoL), cognition, and clinical indicators of depression, pain and functioning were administered at baseline and repeated at 4 weeks' follow-up. Descriptive summary statistics were produced and psychometric analyses were conducted to assess the levels of agreement, convergent validity and known group validity between clinical indicators and HRQoL measures. There was a large divergence in mean (SD) utility scores at baseline for the EQ-5D-5L and DEMQOL-U [EQ-5D-5L mean 0.21 (0.19); DEMQOL-U mean 0.79 (0.14)]. At 4 weeks' follow-up, there was a marked improvement in EQ-5D-5L scores whereas DEMQOL-U scores had deteriorated. [EQ-5D-5L mean 0.45 (0.38); DEMQOL-U mean 0.58 (0.38)]. The EQ-5D and CEQ-5D-5L were more responsive to the physical recovery trajectory experienced by frail older people following surgery to repair a fractured hip, whereas the DEMQOL-U and DEMQOL-Proxy-U appeared more responsive to the changes in delirium and dementia symptoms often experienced by frail older people in this period. This study presents important insights into the HRQoL of a relatively under-researched population of post-hospitalisation frail older people in residential care. Further research should investigate the implications for economic evaluation of self-complete versus proxy assessment of HRQoL and the choice of preference-based instrument for the measurement and valuation of HRQoL in older people exhibiting cognitive decline, dementia and other co-morbidities.

  2. Psychometric properties of the Spanish version of the Collective Efficacy Questionnaire for Sports.

    PubMed

    Román Martínez, Julio; Guillén, Félix; Feltz, Deborah

    2011-08-01

    The present study analyses the psychometric properties of the Spanish version of the Collective Efficacy Questionnaire in Sports (CEQS). The sample comprises 312 athletes (167 males and 145 females), with a mean age of 24.09 (SD= 6.67), with diverse performance levels (professional, semiprofessional and university level), all practitioners of team sports. The factor structure of the questionnaire was analyzed with confirmatory factor analysis (CFA). The results confirm the 5-factor internal structure of the CESQ (Effort, Ability, Unity, Perseverance and Preparation), made up of four items each. We also found acceptable values of the alpha coefficient, which confirms that the CESQ is a reliable instrument. Lastly, we found preliminary support for the validity of the construct of the CESQ, which is sufficient evidence to justify its use to measure the collective efficacy in Spanish athletes.

  3. Environmental Compliance Guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1981-02-01

    The Guide is intended to assist Department of Energy personnel by providing information on the NEPA process, the processes of other environmental statutes that bear on the NEPA process, the timing relationships between the NEPA process and these other processes, as well as timing relationships between the NEPA process and the development process for policies, programs, and projects. This information should be helpful not only in formulating environmental compliance plans but also in achieving compliance with NEPA and various other environmental statutes. The Guide is divided into three parts with related appendices: Part I provides guidance for developing environmental compliancemore » plans for DOE actions; Part II is devoted to NEPA with detailed flowcharts depicting the compliance procedures required by CEQ regulations and Department of Energy NEPA Guidelines; and Part III contains a series of flowcharts for other Federal environmental requirements that may apply to DOE projects.« less

  4. Study of continuous precipitation of ADU for the implantation in the pilot installation at the Atomic Energy Institute, Brazil. Estudo de precipitacao continua de DUA para a implantacao na instalacao piloto CEQ-IEA (in Portuguese)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Araujo, Jose Adroalado de

    1974-05-15

    The paper deals with the ammonium diuranate continuous precipitation with a high chemical purity degree from uranyl nitrate solutions, using 1.2 and 2.4 ammonium hydroxide solutions and gaseous NH{sub 3} as a precipitating agent. The precipitations were carried out in a continuous procedure with one and two stages. The variables studied were the NH[sub 4}OH solutions concentration, ADU precipitation curve, the flow rate of reactants, the temperature of the precipitation, pH of the suspended ADU, and ammonium diuranate filtrability. The experimental work performed and the data obtained permitted the design of a chemical reactor for the continuous nuclear grade ADUmore » precipitation at the Chemical Engineering Department of the Atomic Energy Institute of Sao Paulo.« less

  5. Development of an attention-touch control for manual cervical distraction: a pilot randomized clinical trial for patients with neck pain.

    PubMed

    Gudavalli, M Ram; Salsbury, Stacie A; Vining, Robert D; Long, Cynthia R; Corber, Lance; Patwardhan, Avinash G; Goertz, Christine M

    2015-06-05

    Manual cervical distraction (MCD) is a traction-based therapy performed with a manual contact over the cervical region producing repeating cycles while patients lie prone. This study evaluated a traction force-based minimal intervention for use as an attention-touch control in clinical trials of MCD for patients with chronic neck pain. We conducted a mixed-methods, pilot randomized clinical trial in adults with chronic neck pain. Participants were allocated to three traction force ranges of MCD: low force/minimal intervention (0-20 N), medium force (21-50 N), or high force (51-100 N). Clinicians delivered five treatments over two weeks consisting of three sets of five cycles of MCD at the C5 vertebra and occiput. Traction forces were measured at each treatment. Patient-reported outcomes included a pain visual analogue scale (VAS), Neck Disability Index (NDI), Credibility and Expectancy Questionnaire (CEQ), and adverse effects. A qualitative interview evaluated treatment group allocation perceptions. We randomized 48 participants, allocating an average of five each month. Forty-five participants completed the trial with three participants lost to follow-up. Most participants were women (65%) and white (92%) with a mean (SD) age of 46.8 (12.5) years. Mean traction force values were within the prescribed force ranges for each group at the C5 and occiput levels. Neck pain VAS demonstrated a benefit for high traction force MCD compared to the low force group [adjusted mean difference 15.6; 95% confidence interval (CI) 1.6 to 29.7]. Participants in the medium traction force group demonstrated improvements in NDI compared to the low force group (adjusted mean difference 3.0; 95% CI 0.1 to 5.9), as did participants in the high traction force group (adjusted mean difference 2.7; 95% CI -0.1 to 5.6). CEQ favored the high force group. Most low force participants correctly identified their treatment allocation in the qualitative interview. No serious adverse events were documented. This pilot study demonstrated the feasibility of a clinical trial protocol and the utility of a traction-based, minimal intervention as an attention-touch control for future efficacy trials of MCD for patients with neck pain. ClinicalTrials.gov NCT01765751 (Registration Date 30 May 2012).

  6. Environmental Assessment for the Transfer of 1100 AREA, Southern Rail Connection and Rolling Stock, Hanford Site, Richland, Washington

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    N /A

    This environmental assessment (EA) has been prepared to assess potential environmental impacts associated with the U.S. Department of Energy's proposed action: the transfer of the 1100 Area, southern rail connection and rolling stock to a non-federal entity. Impact information contained herein will be used by the U.S. Department of Energy, Richland Operations Office Manager, to determine if the proposed action is a major federal action significantly affecting the quality of the human environment. If the proposed action is determined to be major and significant, an environmental impact statement will be prepared. If the proposed action is determined not to bemore » major and significant, a Finding of No Significant Impact (FONSI) will be issued and the action can proceed. Criteria used to evaluate significance can be found in Title 40, Code of Federal Regulations (CFR) 1508.27. This EA was prepared in compliance with the ''National Environmental Policy Act'' (NEPA) of 1969, as amended, the Council on Environmental Quality (CEQ) Regulations for Implementing the Procedural Provisions of NEPA (40 CFR 1500-1508), and the U.S. Department of Energy Implementing Procedures for NEPA (10 CFR 1021). The following is a description of each section of the EA. (1) Purpose and Need for Action. This provides a brief statement concerning the problem or opportunity the U.S. Department of Energy is addressing with the proposed action. As necessary, background information is provided. (2) Description of the Proposed Action. A description with sufficient detail to identify potential environmental impacts is provided. (3) Alternatives to the Proposed Action. Reasonable alternative actions, which would address the Purpose and Need, are described. A no action alternative, as required by 10 CFR 1021, also is described. (4) Affected Environment. This provides a brief description of the locale in which the proposed action takes place, and which may be environmentally impacted. (5) Environmental Impacts. The range of environmental impacts, beneficial and adverse, are described for the proposed action. Impacts of alternatives briefly are discussed. (6) Permits and Regulatory Requirements. A brief description of permits and regulatory requirements for the proposed action is provided. (7) Organizations Consulted. Any outside agencies, groups, or individuals contacted as part of environmental assessment documentation preparation are listed. (8) References. Documents used to provide information or data are listed. The appendices contain additional information necessary to support an understanding of the proposed action, alternatives, and potential impacts is provided. Comments resulting from review of the environmental assessment by states and tribes or other stakeholders and the response to those comments will be included in the appendices.« less

  7. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 7. (Fahey Watts Architects-General Contract and Sales)

    DTIC Science & Technology

    1989-01-01

    0 -m Il 5 ))40 . I: 0 40-4-4 -x000) of I 00-4qN< 66 ."eN *-4NI g - *N .40)-4 .4 U1.4 MOMO t00 m m’ C-eq an .- 4-4 eqI 0 .-44 1 ::-4...991 M (0N lice x W (A 4 4C (5n ( U) n44 1-44e mlt w. < Z 91 (0N eq4 c 0 a >- 0 0u >- >- 00X 1- 0 1-0o 1- cc I-- 0 0 C I M C14 91 -4 W. cc . 5 0D 0 -. 1 .1...001 - 00 IO 0 ( NC1n1- 1-1 C90 1 M 4 I 9(no0 1-- 0 4C 0 . 4 4 ~i 0 - 5 <C 4 ZNNZ 0 91 0 j

  8. Comparison of four kinds of extraction techniques and kinetics of microwave-assisted extraction of vanillin from Vanilla planifolia Andrews.

    PubMed

    Dong, Zhizhe; Gu, Fenglin; Xu, Fei; Wang, Qinghuang

    2014-04-15

    Vanillin yield, microscopic structure, antioxidant activity and overall odour of vanilla extracts obtained by different treatments were investigated. MAE showed the strongest extraction power, shortest time and highest antioxidant activity. Maceration gave higher vanillin yields than UAE and PAE, similar antioxidant activity with UAE, but longer times than UAE and PAE. Overall odour intensity of different vanilla extracts obtained by UAE, PAE and MAE were similar, while higher than maceration extracts. Then, powered vanilla bean with a sample/solvent ratio of 4 g/100 mL was selected as the optimum condition for MAE. Next, compared with other three equations, two-site kinetic equation with lowest RMSD and highest R²(adj) was shown to be more suitable in describing the kinetics of vanillin extraction. By fitting the parameters C(eq), k₁, k₂, and f, a kinetics model was constructed to describe vanillin extraction in terms of irradiation power, ethanol concentration, and extraction time. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. A simple approach for assessing equilibrated Kt/V beta 2-M on a routine basis.

    PubMed

    Casino, Francesco G; Pedrini, Luciano A; Santoro, Antonio; Mandolfo, Salvatore; David, Salvatore; De Cristofaro, Vincenzo; Teatini, Ugo; Lomonte, Carlo; Lopez, Teodoro

    2010-09-01

    Large observational studies have shown a reduction in morbidity and mortality in patients on high-flux haemodialysis (HD) or convective techniques, compared with low-flux HD. An index to evaluate treatment efficiency in middle molecule (MM) removal would be recommended. Since beta-2-microglobulin (beta2-M) is a recognized MM marker, we evaluated an easy approach for Kt/V(beta2-M) assessment on a routine basis, avoiding other complex methods. An equation that estimates single-pool (sp) Kt/V(beta2-M) was derived from Leypoldt's formula, which calculates beta2-M dialyser clearance (K(beta2-M)) from the post/pre-dialysis beta2-M concentration (C(t)/C(0)) ratio and the weight loss/end-dialysis weight (Delta W/W) ratio. Our equation, spKt/V(beta2-M) = 6.12 Delta W/W [1 - ln(C(t)/C(0))/ln(1 + 6.12 Delta W/W)], was derived by assuming urea distribution volume (V(u)) as 49% of W and beta2-M volume (V(beta2-M)) as V(u)/3, in agreement with the average patient values in the HEMO Study. The spKt/V(beta2-M) values calculated with our equation (F) in 129 patients on 407 sessions of different high-flux treatments were compared with those calculated with the method applied in the HEMO Study (HM). Equilibrated beta2-M concentration (C(eq)) of the same sessions was also estimated with the equation for C(eq) by Tattersall, and equilibrated Kt/V (eKt/V(beta2-M)) was calculated by introducing Tattersall's equation into our simplified spKt/V(beta2-M) formula. Mean results of our spKt/V(beta2-M) equation (F) were very close to those of the HM method (1.48 +/- 0.38 vs 1.47 +/- 0.37). The difference was less than +/-0.1 in 95% of cases. A mean end-session beta2-M rebound of 44 +/- 14% was predicted, which caused a mean reduction in actual Kt/V(beta2-M) of ~27% (eKt/V(beta2-M) = 1.08 +/- 0.26). The method proposed to estimate spKt/V(beta2-M) and eKt/V(beta2-M) could become a simple tool to monitor the efficiency of high-flux HD and convective techniques and to evaluate the adequacy of treatments in terms of MM removal. Moreover, it might help to better understand the effects of different dialysis schedules. Validation on a larger dialysis population is required.

  10. 76 FR 26996 - Notice of Intent To Prepare an Environmental Impact Statement for New Corporate Average Fuel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ...Pursuant to the National Environmental Policy Act (NEPA), NHTSA plans to prepare an Environmental Impact Statement (EIS) to analyze the potential environmental impacts of the agency's Corporate Average Fuel Economy program for passenger automobiles (referred to herein as ``passenger cars'') and non-passenger automobiles (referred to herein as ``light trucks''). The EIS will consider the potential environmental impacts of new fuel economy standards for model years 2017-2025 passenger cars and light trucks that NHTSA will be proposing pursuant to the Energy Independence and Security Act of 2007. This notice initiates the NEPA scoping process by inviting comments from Federal, State, and local agencies, Indian tribes, and the public to help identify the environmental issues and reasonable alternatives to be examined in the EIS. This notice also provides guidance for participating in the scoping process and additional information about the alternatives NHTSA expects to consider in its NEPA analysis. In preparing this notice, NHTSA has shared the document with the Council on Environmental Quality (CEQ), the Environmental Protection Agency (EPA), and the Department of Energy (DOE).

  11. Measurements of the microwave spectrum, Re-H bond length, and Re quadrupole coupling for HRe(CO)5

    NASA Astrophysics Data System (ADS)

    Kukolich, Stephen G.; Sickafoose, Shane M.

    1993-11-01

    Rotational transition frequencies for rhenium pentacarbonyl hydride were measured in the 4-10 GHz range using a Flygare-Balle type microwave spectrometer. The rotational constants and Re nuclear quadrupole coupling constants for the four isotopomers, (1) H187Re(CO)5, (2) H185Re(CO)5, (3) D187Re(CO)5, and (4) D185Re(CO)5, were obtained from the spectra. For the most common isotopomer, B(1)=818.5464(2) MHz and eq Q(187Re)=-900.13(3) MHz. The Re-H bond length (r0) determined by fitting the rotational constants is 1.80(1) Å. Although the Re atom is located at a site of near-octahedral symmetry, the quadrupole coupling is large due to the large Re nuclear moments. A 2.7% increase in Re quadrupole coupling was observed for D-substituted isotopomers, giving a rather large isotope effect on the quadrupole coupling. The Cax-Re-Ceq angle is 96(1)°, when all Re-C-O angles are constrained to 180°.

  12. Hydropower Licensing as a Bridge between Climate Science and Applications: Creating Actionable Science for Regulatory Decisionmaking

    NASA Astrophysics Data System (ADS)

    Ray, A. J.; Barsugli, J. J.; Walker, S. H.

    2016-12-01

    The Integrated Licensing Process (ILP) of the US Federal Energy Regulatory Commission (FERC) is an example of an existing regulatory process that has the capacity to bridge the gap between science and decision making by clearly delineating existing science, the climate-regulatory nexus, and additional scientific work needed to inform licensing or relicensing of non-federal hydropower projects. In a parallel, but interacting set of legal and regulatory processes, NOAA's National Marine Fisheries Service (NMFS) must conduct analyses based on the best available science in order to implement the requirements of the Endangered Species Act (ESA), the Magnuson-Stevens Act, and NEPA, and to develop terms and conditions to protect fisheries for the 30-50 year term of the license and the longer life of the project itself. Therefore, NMFS must understand the combined effects of hydropower projects and climate change to fulfill its own mandates to protect anadromous fish, protected species and habitat. Federal Executive Order (EO) #13693 on climate change sustainability require use of climate risks in planning, also recommended in NOAA's own guidance on implementing ESA, and the Council on Environmental Quality (CEQ) guidance on implementing NEPA; however, as an independent agency FERC is not subject to that EO. In the past, FERC has consistently rejected NMFS' climate study requests, stating, among other reasons, that climate science is `too uncertain,' and therefore not actionable. Thus, in order for NMFS to get the information needed for its own decision process, NOAA must first persuade FERC that the science is actionable. This presentation will describe our experiences in a multi-year effort by an interdisciplinary team of climate and fishery scientists to develop acceptable climate study requests that address FERC's concerns about uncertainty, for the Susitna-Watana project on Alaska's Susitna River, the LaGrange Project on the Tuolumne R. in California, and the Hiram Project on the Saco R. in Maine. Furthermore, we document that climate studies are needed to meet FERC's own standard that study methodologies be "generally accepted practice" in the community, i.e., that water infrastructure planning and management has evolved to include use of climate risk assessments as best practices.

  13. E-cigarette versus nicotine inhaler: comparing the perceptions and experiences of inhaled nicotine devices.

    PubMed

    Steinberg, Michael B; Zimmermann, Mia Hanos; Delnevo, Cristine D; Lewis, M Jane; Shukla, Parth; Coups, Elliot J; Foulds, Jonathan

    2014-11-01

    Novel nicotine delivery products, such as electronic cigarettes (e-cigarettes), have dramatically grown in popularity despite limited data on safety and benefit. In contrast, the similar U.S. Food and Drug Administration (FDA)-approved nicotine inhaler is rarely utilized by smokers. Understanding this paradox could be helpful to determine the potential for e-cigarettes as an alternative to tobacco smoking. To compare the e-cigarette with the nicotine inhaler in terms of perceived benefits, harms, appeal, and role in assisting with smoking cessation. A cross-over trial was conducted from 2012 to 2013 PARTICIPANTS/INTERVENTIONS: Forty-one current smokers age 18 and older used the e-cigarette and nicotine inhaler each for 3 days, in random order, with a washout period in between. Thirty-eight participants provided data on product use, perceptions, and experiences. The Modified Cigarette Evaluation Questionnaire (mCEQ) measured satisfaction, reward, and aversion. Subjects were also asked about each product's helpfulness, similarity to cigarettes, acceptability, image, and effectiveness in quitting smoking. Cigarette use was also recorded during the product-use periods. The e-cigarette had a higher total satisfaction score (13.9 vs. 6.8 [p < 0.001]; range for responses 3-21) and higher reward score (15.8 vs. 8.7 [p < 0.001]; range for responses 5-35) than the inhaler. The e-cigarette received higher ratings for helpfulness, acceptability, and "coolness." More subjects would use the e-cigarette to make a quit attempt (76 %) than the inhaler (24 %) (p < 0.001). Eighteen percent (7/38) of subjects abstained from smoking during the 3-day periods using the e-cigarette vs. 10 % (4/38) using the inhaler (p = 0.18). The e-cigarette was more acceptable, provided more satisfaction, and had higher perceived benefit than the inhaler during this trial. E-cigarettes have the potential to be important nicotine delivery products owing to their high acceptance and perceived benefit, but more data are needed to evaluate their actual efficacy and safety. Providers should be aware of these issues, as patients will increasingly inquire about them.

  14. Competition of wormholes during the evolution of cave passages

    NASA Astrophysics Data System (ADS)

    Gabrovsek, Franci; Dreybrodt, Wolfgang

    2017-04-01

    Reactive fronts in two-dimensional plane parallel fractures, with constant head difference between input and output and with diffusion controlled first order reaction rates R = keff ṡ (Ceq - C), where keff = k ṡ (1 + ka/6D)-1, are instable to infinitesimal perturbations in fracture aperture width (1), causing spontaneous fingering of the reactive front resulting in the formation of wormholes. C is the actual concentration and Ceq the equilibrium concentration, a, is the actual aperture width of the fracture , and D the constant of molecular diffusion. Fingering happens also in plane-parallel rough fractures where it is triggered by the existence of statistically more favorable pathways. The same behavior is observed in rectangular two-dimensional networks of "one-dimensional" smooth fractures used in modeling the evolution of caves in soluble rock (2). Here the formation of caves can be regarded as the evolution of wormholes along the two-dimensional network. Once fingering has been triggered, either by instability or by roughness, many small fingers compete with each other and only a few survive. Here we investigate the competition between two seeded fingers in initially homogeneous fracture networks with identical aperture width of all fractures and also in inhomogeneous ones where the aperture widths are distributed log normally. In both cases our modeling reveals the rules of competition: By instability one of the fingers grows faster than its competitor therefore penetrating somewhat deeper. As a consequence the hydraulic head at its tip is higher than that close to the tip of the shorter finger. Therefore the fractures connecting the tip regions of both fingers carry flow from the deep finger to the tip region of its competitor. This cross-flow is replaced by increasing inflow of aggressive solution into the input of the winner, enhancing further dissolution and growth. On the other hand the cross-flow increases the head at the tip of the losing finger, and consequently decreases inflow of aggressive solution into it, thus inhibiting its further evolution. This mechanism supports further growth of the winner (wormhole) and stops the growth of its competitor. Similar competition happens in the case of several fingers competing. In any case we observe flow from the winning fingers to the loosing ones. The communication between the competitors is always established by cross flow between its tip regions. We will present various scenarios of wormhole formation, which demonstrate details of the competition of fingers arising from either the reactive instability or from the statistical distribution of fracture aperture widths. In conclusion we find that the initiation of wormholes results either from instability or from the statistical distribution of favorable pathways. Once growth of fingers has been initiated the evolution of the wormhole patterns becomes deterministic. (1) Szymczak, P., and A.J.C. Ladd (2011), The initial stages of cave formation: Beyond the one-dimensional paradigm, Earth Planet. Sci. Lett. 301, 424-432 (2) Dreybrodt, W., Gabrovšek, F., Romanov, D.(2005) Processes of Speleogenesis: A Modeling Approach. ZRC Publishing, Karst Research Institute at ZRC SAZU, Ljubljana

  15. The effect of natural and anthropogenic factors on sorption of copper in chernozem

    NASA Astrophysics Data System (ADS)

    Bauer, Tatiana; Minkina, Tatiana; Mandzhieva, Saglara; Pinskii, David; Linnik, Vitaly; Sushkova, Svetlana

    2016-04-01

    The aim of this work was to study the effect of the attendant anions and particle-size distribution on the adsorption of copper by ordinary chernozem. Solutions of HM nitrates, acetates, chlorides, and sulfates were used to study the effect of the chemical composition of added copper salts on the adsorption of copper by an ordinary chernozem. Samples of the soil sieved through a 1-mm sieve in the natural ionic form and soil fraction with different particle size (clay - the particle with size < 1μm and physical clay < 10 μm) were treated with solutions of the corresponding copper salts at a soil : solution ratio of 1:10. The concentrations of the initial copper solutions were 0.02, 0.05, 0.08, 0.1, 0.3, 0.5, and 1.0 mM/L. The range of Cu2+ concentrations in the studied system covers different geochemical situations corresponding to the actual levels of soil contamination with the metal under study. The suspensions were shaken for 1 h, left to stand for 24 h, and then filtered. The contents of the HM in the filtrates were determined by atomic absorption spectrometry (AAS). The contents of the adsorbed copper cations were calculated from the difference between the metal concentrations in the initial and equilibrium solutions. The isotherms of copper adsorption from the metal nitrate, chloride, and sulfate solutions have near linear shapes and, hence, can be satisfactorily described by a Henry or Freundlich equation: Cads = KH •Ceq.(1) Cads = KF •Ceqn,(2) where Cadsis the content of the adsorbed cations, mM/kg soil;Ceq is the concentration of copper in the equilibrium solution, mM/L; KH and KF denote the Henry and Freundlich adsorption coefficients, respectively, kg/L. The isotherm of Cu2+ adsorption by ordinary chernozem from acetate solutions is described by the Langmuir equation: Cads = C∞ÊLC / (1 + ÊLC), (3) where Cadsis the content of the adsorbed cations, mM/kg soil;C∞ is the maximum adsorption of the HM, mM/kg soil; ÊL is the affinity constant, L/mM; C is the concentration of the HM in the equilibrium solution, mM/L. According to the values of KH, the binding strength of the copper cations adsorbed from different salt solutions decreases in the series: Cu(Ac)2(1880,5± 76,2) > CuCl2(1442,8±113,5) > Cu(NO3)2(911,4 ± 31,1) >> CuSO4(165,3 ± 12,9). Thus, copper is most strongly adsorbed from the acetate solution and least strongly from the sulfate solution. The adsorption of copper by clay and physical clay fractions from the ordinary chernozem was of limited character and followed the (3) equation. In the particle-size fractions separated from the soils, the concentrations of copper decreased with the decreasing particle size. The values of ÊL and C∞characterizing the HM adsorption by the chernozem and its particle-size fractions formed the following sequence: clay (80,20±20,29 and 28,45±0,46 > physical clay (58,20±14,54 and 22,15±1,22) > entire soil (38,80±12,33 and 17,58±3,038). This work was supported by the Russian Ministry of Education and Science, project no. 5.885.2014/K, Russian Foundation for Basic Research, projects no. 14-05-00586 À

  16. Evaluating belinjau (Gnetum gnemon L.) seed flour quality as a base for development of novel food products and food formulations.

    PubMed

    Bhat, Rajeev; binti Yahya, Nabilah

    2014-08-01

    Belinjau (Gnetum gnemon L.) seed flour was evaluated for nutritional composition, antioxidant activity and functional properties. Seed flour was found to be rich in protein (19.0g/100g), crude fibre (8.66g/100g), carbohydrates (64.1%), total dietary fibre (14.5%) and encompassed adequate amounts of essential amino acids, fatty acids and minerals. Antioxidant compounds such as total phenols (15.1 and 12.6mgGAE/100g), tannins (35.6 and 16.1mgCE/100g) and flavonoids (709 and 81.6mgCEQ/100g) were higher in ethanolic extracts over aqueous extracts, respectively. Inhibition of DPPH was high in ethanol extracts (48.9%) compared to aqueous extracts (19.7%), whereas aqueous extracts showed a higher FRAP value compared to ethanol extracts (0.98 and 0.61mmolFe(II)/100g, respectively). Results on functional properties revealed acceptable water and oil absorption capacities (5.51 and 1.98g/g, respectively), emulsion capacity and stability (15.3% and 6.90%, respectively), and foaming capacity (5.78%). FTIR spectral analysis showed seed flour to encompass major functional groups such as: amines, amides, amino acids, polysaccharides, carboxylic acids, esters and lipids. As belinjau seed flour possesses a rich nutraceutical value, it has high potential to be used as a basic raw material to develop new low cost nutritious functional foods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Quasi-steady Bingham plastic analysis of an electrorheological flow mode bypass damper with piston bleed

    NASA Astrophysics Data System (ADS)

    Lindler, Jason; Wereley, Norman M.

    2003-06-01

    We present an improved experimental validation of our nonlinear quasi-steady electrorheological (ER) and magnetorheological damper analysis, using an idealized Bingham plastic shear flow mechanism, for the flow mode of damper operation with leakage effect. To validate the model, a double-acting ER valve or bypass damper was designed and fabricated. Both the hydraulic cylinder and the bypass duct have cylindrical geometry, and damping forces are developed in the annular bypass via Poiseuille flow. The ER fluid damper contains a controlled amount of leakage around the piston head. The leakage allows ER fluid to flow from one side of the piston head to the opposite side without passing through the ER bypass. For this flow mode damper, the damping coefficient, defined as the ratio of equivalent viscous damping of the Bingham plastic material, Ceq, to the Newtonian viscous damping, C, is a function of the non-dimensional plug thickness only. The damper was tested for varying conditions of applied electric field and frequency using a mechanical damper dynamometer. In this analysis, the leakage damping coefficient with incorporated leakage effects, predict the amount of energy dissipated for a complete cycle of the piston rod. Measured force verses displacement cycles for multiple frequencies and electric fields validate the ability of the non-dimensional groups and the leakage damping coefficient to predict the damping levels for an ER bypass damper with leakage. Based on the experimental validation of the model using these data, the Bingham plastic analysis is shown to be an effective tool for the analysis-based design of double-acting ER bypass dampers.

  18. Optimizing extraction conditions of crude fiber, phenolic compounds, flavonoids and antioxidant activity of date seed powder.

    PubMed

    Afifi, Hanan S; Hashim, Isameldin B; Altubji, Sabreen I

    2017-12-01

    The objective of this study was to optimize the extraction conditions of crude fiber, phenolic compounds, flavonoids, and antioxidant activity from date seeds powder, using Response Surface Methodology. A central composite design with four independent variables; concentration of ethanol (X 1  = 25, 50 and 75% v/v), solvent: sample ratio (X 2  = 40:1, 50:1 and 60:1 v/w), temperature (X 3  = 45, 55 and 65 °C), and extraction time (X 4  = 1, 2 and 3 h) and a three level face centered cube design were used. A total of twenty nine experimental runs with five replicates at the central point were used to study the response variables using two extraction cycles. Maximum phenolic compound content (71.6 mg GAE/100 g) was extracted using 50% ethanol solution with 40:1 solvent: sample ratio for 1 h at 55 °C. While the maximum antioxidant activity (55.02 µmol Fe(II)/g) was obtained using similar ethanol concentration and solvent: sample ratio except at lower temperature (45 °C) for 2 h. On other hand, the maximum flavonoids content (455.77 mg CEQ/100 g) was reached by using 50% concentration, 50:1 solvent: sample ratio at 65 °C for 3 h. In contrast, the content of fiber was not affected by the different extraction conditions. Results indicate that using combination of extracted conditions, have a great potential for extracting all depending compounds except crude fiber.

  19. Study on the luminescence behavior of sulfobutylether-β-cyclodextrin with risperidone and its analytical application.

    PubMed

    Wu, Min; Chen, Donghua; Song, Zhenghua

    2012-10-01

    The interaction of sulfobutylether-β-cyclodextrin (SBE-β-CD) with risperidone (RISP) was first described with luminol-SBE-β-CD chemiluminescence (CL) system by flow injection analysis (FIA). In luminol-SBE-β-CD CL system, the 1:1 SBE-β-CD···luminol(*) complexation could enhance CL intensity of luminol and produce the effect of complexation enhancement of CL (CEC). It was found that RISP could quench the CL intensity of SBE-β-CD···luminol(*) and caused the effect of complexation enhancement of quenching (CEQ), the formation constant K(R-CD) 3.4×10(4) L mol(-1) and the stoichiometric ratio 1:1 of RISP···SBE-β-CD complex were obtained by the proposed CL model. Association degree α 0.036 of RISP···SBE-β-CD complex was also given by CL method. Based on the linear relationship to the decrement of luminol-SBE-β-CD-RISP CL intensity and the logarithm of RISP concentration, RISP also can be quantified in the linear range of 3.0-500.0 nmol L(-1) with a detection limit of 1.0 nmol L(-1) (3σ). The proposed method was successfully applied to monitoring excreted RISP in human urine. It was found that RISP reached its maximum after oral administration for 1.5 h with the total excretion of 14.26% within 8.5 h; the elimination rate constant k and half-life time t(1/2) were 0.474 and 1.5 h, respectively. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    N /A

    The ''National Environmental Policy Act of 1969'' (NEPA) requires Federal agency officials to consider the environmental consequences of their proposed actions before decisions are made. In complying with NEPA, the United States (U.S.) Department of Energy (DOE) follows the Council on Environmental Quality (CEQ) regulations (40 Code of Federal Regulations [CFR] 1500-1508) and DOE's NEPA implementing procedures (10 CFR 1021). The purpose of an Environmental Assessment (EA) is to provide Federal decision makers with sufficient evidence and analysis to determine whether to prepare an Environmental Impact Statement (EIS) or issue a Finding of No Significant Impact. In this case, themore » DOE decision to be made is whether to construct and operate a 19.5-mile (mi) (31-kilometer [km]) electric transmission line (power line) reaching from the Norton Substation, west across the Rio Grande, to locations within the Los Alamos National Laboratory (LANL) Technical Areas (TAs) 3 and 5 at Los Alamos, New Mexico. The construction of one electric substation at LANL would be included in the project as would the construction of two line segments less than 1,200 feet (ft) (366 meters [m]) long that would allow for the uncrossing of a portion of two existing power lines. Additionally, a fiber optics communications line would be included and installed concurrently as part of the required overhead ground conductor for the power line. The new power line would improve the reliability of electric service in the LANL and Los Aktrnos County areas as would the uncrossing of the crossed segments of the existing lines. Additionally, installation of the new power line would enable the LANL and the Los Alamos County electric grid, which is a shared resource, to be adapted to accommodate the future import of increased power when additional power service becomes available in the northern New Mexico area. Similarly, the fiber optics line would allow DOE to take advantage of future opportunities in enhanced communications services. The objectives of this EA are to (1) describe the baseline environmental conditions at the proposed power line location, (2) analyze the potential effects to the existing environment from construction, operation, and maintenance of a new power line, and (3) compare the effects of the Proposed Action and the four action alternatives to the No Action Alternative. In addition, the EA provides DOE with environmental information that could be used in developing mitigative actions to minimize or avoid adverse effects to the integrity of the human environment and natural ecosystems should DOE decide to proceed with construction and operation of the new power line. Ultimately, the goal of NEPA and this EA is to aid DOE officials in making decisions based on understanding the environmental consequences of their decision.« less

  1. Data Call Response for NEPA Supplement Analysis of CMRR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Booth, Steven Richard

    The Department of Energy/National Nuclear Security Administration (DOE/NNSA) is proposing to provide analytical chemistry (AC) and materials characterization (MC) capabilities at the Los Alamos National Laboratory (LANL) by using a combination of existing space in two existing buildings: the Radiological Laboratory/Utility/Office Building (RLUOB) and the Plutonium Facility, Building 4 (PF-4) in TA-55. This represents a change from decisions made by DOE as informed by previous National Environmental Policy Act (NEPA) analyses. In accordance with Council on Environmental Quality (CEQ) and DOE requirements, NNSA is preparing a Supplement Analysis (SA) to evaluate the potential environmental impacts of the proposed action. Themore » focus of this analysis is on determining whether the proposal to provide AC and MC laboratory capabilities in existing space in RLUOB and PF-4 rather than building a new nuclear facility (NF) is a substantial change that is relevant to environmental concerns or whether new circumstance or information relevant to environmental concerns and bearing on the proposed action or its impacts are significant. The end result of the analysis is a determination whether the existing Chemistry and Metallurgy Research Building Replacement Environmental Impact Statement (CMRR EIS) should be supplemented, a new EIS should be prepared, or no further NEPA analysis is necessary. This report provides data for incorporation into the Supplement Analysis being written by Leidos, Inc. under contract to NNSA. Responding to the data call requires several areas of expertise. Los Alamos subject matter experts estimate equipments lists, facility modifications, waste quantities, labor needs and radiological doses. Los Alamos NEPA experts assist Leidos in compiling existing data from the LANL Site-Wide Environmental Impact Statement (SWEIS) and CMRR EIS for public and other impacts. Bounding conditions are used to determine NEPA estimates.« less

  2. Soil carbon sequestration and biochar as negative emission technologies.

    PubMed

    Smith, Pete

    2016-03-01

    Despite 20 years of effort to curb emissions, greenhouse gas (GHG) emissions grew faster during the 2000s than in the 1990s, which presents a major challenge for meeting the international goal of limiting warming to <2 °C relative to the preindustrial era. Most recent scenarios from integrated assessment models require large-scale deployment of negative emissions technologies (NETs) to reach the 2 °C target. A recent analysis of NETs, including direct air capture, enhanced weathering, bioenergy with carbon capture and storage and afforestation/deforestation, showed that all NETs have significant limits to implementation, including economic cost, energy requirements, land use, and water use. In this paper, I assess the potential for negative emissions from soil carbon sequestration and biochar addition to land, and also the potential global impacts on land use, water, nutrients, albedo, energy and cost. Results indicate that soil carbon sequestration and biochar have useful negative emission potential (each 0.7 GtCeq. yr(-1) ) and that they potentially have lower impact on land, water use, nutrients, albedo, energy requirement and cost, so have fewer disadvantages than many NETs. Limitations of soil carbon sequestration as a NET centre around issues of sink saturation and reversibility. Biochar could be implemented in combination with bioenergy with carbon capture and storage. Current integrated assessment models do not represent soil carbon sequestration or biochar. Given the negative emission potential of SCS and biochar and their potential advantages compared to other NETs, efforts should be made to include these options within IAMs, so that their potential can be explored further in comparison with other NETs for climate stabilization. © 2016 John Wiley & Sons Ltd.

  3. Sorption of methyl tert-butyl ether (MTBE) and tert-butyl alcohol (TBA) to synthetic resins.

    PubMed

    Bi, Erping; Haderlein, Stefan B; Schmidt, Torsten C

    2005-10-01

    Methyl tert-butyl ether (MTBE) is a widely used gasoline oxygenate. Contamination of MTBE and its major degradation product tert-butyl alcohol (TBA) in groundwater and surface water has received great attention. However, sorption affinity and sorption mechanisms of MTBE and TBA to synthetic resins, which can be potentially used in removal of these contaminants from water, in passive sampling, or in enrichment of bacteria, have not been studied systemically. In this study, kinetic and equilibrium sorption experiments (single solute and binary mixtures) on four synthetic resins were conducted. The sorption affinity of the investigated sorbents for MTBE and TBA decreases in the order Ambersorb 563>Optipore L493>Amberlite XAD4>Amberlite XAD7, and all show higher sorption affinity for MTBE than for TBA. Binary experiments with o-xylene, a major compound of gasoline as co-contaminant, imply that all resins preferentially sorb o-xylene over MTBE or TBA, i.e., there is sorption competition. In the equilibrium aqueous concentration (Ceq) range (0.1-139.0 mg/L for MTBE, and 0.01-48.4 mg/L for TBA), experimental and modeling results as well as sorbent characteristics indicate that micropore filling and/or some other type of adsorption process (e.g., adsorption to specific sites of high sorption potential at low concentrations) rather than partitioning were the dominant sorption mechanisms. Optipore L493 has favourable sorption and desorption characteristics, and is a suitable sorbent, e.g., in bacteria enrichment or passive sampling for moderately polar compounds. However, for highly polar compounds such as TBA, Ambersorb 563 might be a better choice, especially in water treatment.

  4. Motivation, expectations, and usability of a driven gait orthosis in stroke patients and their therapists.

    PubMed

    Swinnen, Eva; Lefeber, Nina; Willaert, Ward; De Neef, Fallon; Bruyndonckx, Lyn; Spooren, Annemie; Michielsen, Marc; Ramon, Tine; Kerckhofs, Eric

    2017-05-01

    In the development of efficacious driven gait orthoses (DGO), it is an added value to consider patients' and therapists' perspectives concerning robot-assisted gait training (RAGT). A better understanding of these issues may improve the process of care and outcome. This study aimed to examine stroke patients' motivation and expectations of RAGT, and therapists' expectations and perspectives on the usability of RAGT. Additionally, the differences in expectations between stroke patients and their therapists were analyzed. A cross sectional, multi-center, three-group trial was conducted. Included were (1) stroke patients who have experience with RAGT (i.e. the stroke user group), (2) stroke patients who have no experience with RAGT (i.e. the stroke non-user group), and (3) therapists who have experience with RAGT (i.e. the therapist user group). The Intrinsic Motivation Inventory (IMI), Credibility/Expectancy Questionnaire (CEQ), and Usefulness, Satisfaction and Ease of Use Questionnaire (USE) were used. Descriptive statistics and non-parametric Kruskal-Wallis tests were conducted. In total, 46 subjects were assessed (stroke user group: n = 23, stroke non-user group: n = 14, therapist user group: n = 9). IMI subscale scores ranged from 42 to 88%. Mean credibility and expectancy ranged from 80 to 85% and 57 to 72%, respectively, with no significant differences between groups. USE subscale scores ranged from 61 to 72%. Stroke user group patients seem quite motivated to train with the DGO and both patients and therapists reasonably believe that this training could improve gait functioning. Therapists are moderately satisfied with the usability of the DGO, but there is room for improvement with respect to usefulness and ease of use.

  5. Prefrontal activity during working memory is modulated by the interaction of variation in CB1 and COX2 coding genes and correlates with frequency of cannabis use.

    PubMed

    Taurisano, Paolo; Antonucci, Linda A; Fazio, Leonardo; Rampino, Antonio; Romano, Raffaella; Porcelli, Annamaria; Masellis, Rita; Colizzi, Marco; Quarto, Tiziana; Torretta, Silvia; Di Giorgio, Annabella; Pergola, Giulio; Bertolino, Alessandro; Blasi, Giuseppe

    2016-08-01

    The CB1 cannabinoid receptor is targeted in the brain by endocannabinoids under physiological conditions as well as by delta9-tetrahydrocannabinol under cannabis use. Furthermore, its signaling appears to affect brain cognitive processing. Recent findings highlight a crucial role of cyclooxygenase-2 (COX-2) in the mechanism of intraneuronal CB1 signaling transduction, while others indicate that two single nucleotide polymorphisms (SNPs) (rs1406977 and rs20417) modulate expression of CB1 (CNR1) and COX-2 (PTGS2) coding genes, respectively. Here, our aim was to use fMRI to investigate in healthy humans whether these SNPs interact in modulating prefrontal activity during working memory processing and if this modulation is linked with cannabis use. We recruited 242 healthy subjects genotyped for CNR1 rs1406977 and PTGS2 rs20417 that performed the N-back working memory task during fMRI and were interviewed using the Cannabis Experience Questionnaire (CEQ). We found that the interaction between CNR1 rs1406977 and PTGS2 rs20417 is associated with dorsolateral prefrontal cortex (DLPFC) activity such that specific genotype configurations (CNR1 C carriers/PTGS2 C carriers and CNR1 TT/PTGS2 GG) predict lower cortical response versus others in spite of similar behavioral accuracy. Furthermore, DLPFC activity in the cluster associated with the CNR1 by PTGS2 interaction was negatively correlated with behavioral efficiency and positively correlated with frequency of cannabis use in cannabis users. These results suggest that a genetically modulated balancing of signaling within the CB1-COX-2 pathway may reflect on more or less efficient patterns of prefrontal activity during working memory. Frequency of cannabis use may be a factor for further modulation of CNR1/PTGS2-mediated cortical processing associated with this cognitive process. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. The Embodied Self in Parkinson's Disease: Feasibility of a Single Tango Intervention for Assessing Changes in Psychological Health Outcomes and Aesthetic Experience

    PubMed Central

    Koch, Sabine C.; Mergheim, Katja; Raeke, Judith; Machado, Clarissa B.; Riegner, Eliane; Nolden, Joachim; Diermayr, Gudrun; von Moreau, Dorothee; Hillecke, Thomas K.

    2016-01-01

    Background: Dance is an embodied activity with benefits for mobility, balance, and quality of life (QoL) of persons affected by Parkinson's Disease (PD). It is enjoyable and likely to support adherence to movement prescriptions. The objective of this study was to assess the feasibility of measuring changes in psychological outcomes, specifically well-being, body self-efficacy, outcome expectations, and experienced beauty after a single Argentine Tango intervention in a workshop format. To anchor experienced beauty in a theory, the article introduces a model of embodied aesthetics featuring active art-making as a central aspect of healing in arts-based interventions. Methods: In a single-group pre–post design, we tested the feasibility of measuring psychological changes of 34 PD patients from Southern Germany after an introductory workshop in Argentine Tango. They participated in a 90 min Tango for PD intervention and completed the Heidelberg State Inventory (HSI-24; (Koch et al., 2007)), the Body Self-Efficacy Scale (BSE; (Fuchs and Koch, 2014)) with a sub-dimension on aesthetic experience, and the Credibility-Expectancy Questionnaire (CEQ; (Devilly and Borkovec, 2000)) before and after the intervention. A subgroup completed the therapeutic factors of arts therapies-scale, a new measure to elaborate on the aesthetic experience. We analyzed pre–post-differences with a t-test for paired samples. Results and Discussion: The study supports the feasibility of measuring health-related psychological changes from a single Argentine Tango intervention for PD patients, as well as acceptance and appropriateness of the intervention for the patient group. After the tango intervention, well-being, body self-efficacy, and outcome expectancies increased. Participants also experienced an increase in beauty of their movements and other aesthetic aspects. We suspect that, in addition to the functional and psychological factors identified so far, the aesthetic experience in dance may be an important therapeutic factor mediating several outcomes of dance and other arts-based interventions. A controlled study for evidence-based testing of targeted variables can now follow to examine the new hypotheses. PMID:27458332

  7. Does gasification and biochar amendment provide a viable solution to balance greenhouse gas emissions, energy requirements and orchard residue management?

    NASA Astrophysics Data System (ADS)

    Pereira, Engil; Suddick, Emma; Six, Johan

    2015-04-01

    By converting biomass residue to biochar, we can generate power cleanly and sequester carbon resulting in overall greenhouse gas (GHG) savings when compared to typical fossil fuel burning and waste disposal. This on-farm research study provides a long-term and high frequency assessment of GHG emissions from biochar amended-soils in an organic walnut orchard in the Central Valley of California, USA. We also estimated the GHG offsets from the conversion of walnut residue into energy through gasification at the on-site walnut processing plant. Soil fluxes of carbon dioxide (CO2) and nitrous oxide (N2O) were monitored over 29 months in a 3.6 ha walnut orchard following management and precipitation events. We compared four treatments: control, biochar, compost, and biochar combined with compost. Events involving resource inputs such as fertilization or cover crop mowing induced the largest N2O peaks with average 0.13 kg N2O-N ha-1 day-1, while precipitation events produced the highest CO2 fluxes in average 0.124 Mg CO2-C ha-1 day-1. Biochar alone decreased N2O fluxes in two out of 23 measured events, however, not with enough significant magnitude to modify annual or seasonal totals. This indicates that biochar-induced decreases in N2O fluxes may occasionally occur without significant changes in total emissions. Additionally, biochar alone or in combination with compost did not alter annual or seasonal cumulative CO2 emissions. For this particular study, the conversion of orchard waste into energy and C sequestration through biochar amendment offset 100.3 Mg CO2-Ceq year-1. Thus, given that biochar did not alter cumulative GHG emissions from soils, we conclude that, in the scenario of this study, the use of biochar as a strategy to decrease farm-level GHG emissions is obtained through the gasification of orchard residue into energy and through biochar C sequestration, and not as a tool to decrease soil CO2 and N2O emissions.

  8. Therapeutic properties in Tunisian hot springs: first evidence of phenolic compounds in the cyanobacterium Leptolyngbya sp. biomass, capsular polysaccharides and releasing polysaccharides.

    PubMed

    Trabelsi, Lamia; Mnari, Amira; Abdel-Daim, Mohamed M; Abid-Essafi, Salwa; Aleya, Lotfi

    2016-12-13

    In Tunisia, the use of hot spring waters for both health and recreation is a tradition dating back to Roman times. In fact, thermal baths, usually called "Hammam" are recommended as a therapeutic and prophylactic measure against many types of illness and toxicity. While the chemical concentration of thermal water is admittedly associated with its therapeutic effects, the inclusion in spa waters of efficient bioproduct additives produced by photosynthetic microorganisms and that act against oxidative stress may comprise a significant supplementary value for thermal centers. The aim of this study was to investigate the antioxidant potential of the Tunisian thermophilic cyanobacterium Leptolyngbya sp. and to determine its phytochemical constituents and phenolic profile. BME (Biomass Methanolic Extract), CME (Capsular polysaccharides Methanolic Extract) and RME (Releasing polysaccharides Methanolic Extract) of Leptolyngbya sp. were examined for their antioxidant activities by means of DPPH, hydroxyl radical scavenging and ferrous ion chelating assays. Their total phenols, flavonoids, carotenoids, Mycosporine-like amino acids (MAAs) and vitamin C contents, as well as their phenolic profiles were also determined. BME has the highest content of phenols (139 ± 1.2 mg/g), flavonoids (34.9 ± 0.32 mg CEQ/g), carotenoids (2.03 ± 0.56 mg/g) and vitamin C (15.7 ± 1.55 mg/g), while the highest MAAs content (0.42 ± 0.03 mg/g) was observed in CME. BME presented both the highest DPPH and hydroxyl radical scavenging ability with an IC 50 of 0.07 and 0.38 mg/ml, respectively. The highest ferrous chelating capacity was detected in CME with an IC 50  = 0.59 mg/ml. Phenolic profiles revealed the presence of 25 phenolic compounds with the existence of hydroxytyrosol, oleuropein, resveratrol and pinoresinol. The study demonstrated that the cyanobacterium Leptolyngbya sp. possesses abundant natural antioxidant products which may have prophylactic and therapeutic effects on many types of illness and toxicity. The present findings not only explain and reinforce the rationale behind traditional therapeutic practices in Tunisia in the exploitation of the country's hot springs, but support the addition of Leptolyngbya to thermal waters as a means to enhance the value and reputation of the curative nature of Tunisian thermal waters.

  9. Greenhouse gas impacts of declining hydrocarbon resource quality: Depletion, dynamics, and process emissions

    NASA Astrophysics Data System (ADS)

    Brandt, Adam Robert

    This dissertation explores the environmental and economic impacts of the transition to hydrocarbon substitutes for conventional petroleum (SCPs). First, mathematical models of oil depletion are reviewed, including the Hubbert model, curve-fitting methods, simulation models, and economic models. The benefits and drawbacks of each method are outlined. I discuss the predictive value of the models and our ability to determine if one model type works best. I argue that forecasting oil depletion without also including substitution with SCPs results in unrealistic projections of future energy supply. I next use information theoretic techniques to test the Hubbert model of oil depletion against five other asymmetric and symmetric curve-fitting models using data from 139 oil producing regions. I also test the assumptions that production curves are symmetric and that production is more bell-shaped in larger regions. Results show that if symmetry is enforced, Gaussian production curves perform best, while if asymmetry is allowed, asymmetric exponential models prove most useful. I also find strong evidence for asymmetry: production declines are consistently less steep than inclines. In order to understand the impacts of oil depletion on GHG emissions, I developed the Regional Optimization Model for Emissions from Oil Substitutes (ROMEO). ROMEO is an economic optimization model of investment and production of fuels. Results indicate that incremental emissions (with demand held constant) from SCPs could be 5-20 GtC over the next 50 years. These results are sensitive to the endowment of conventional oil and not sensitive to a carbon tax. If demand can vary, total emissions could decline under a transition because the higher cost of SCPs lessens overall fuel consumption. Lastly, I study the energetic and environmental characteristics of the in situ conversion process, which utilizes electricity to generate liquid hydrocarbons from oil shale. I model the energy inputs and outputs from the ICP use them to calculate the GHG emissions from the ICP. Energy outputs (as refined liquid fuel) range from 1.2 to 1.6 times the total primary energy inputs. Well-to-tank greenhouse gas emissions range from 30.6 to 37.1 gCeq./MJ of final fuel delivered, 21 to 47% larger than those from conventionally produced petroleum-based fuels.

  10. Assessment of on-road transportation demand and CO2 emissions for determination of air quality impacts from the Megacity of São Paulo

    NASA Astrophysics Data System (ADS)

    Perez-Martinez, P. J.; Miranda, R. M.; Andrade, M. D. F.

    2017-12-01

    In this manuscript we assess the capability of using mobility surveys and a high-scale assignment and emission model to study climate change and air quality impacts related to on-road transportation in the Megacity of São Paulo (MSP). Initially, we estimate CO2 emissions of light and heavy vehicles (LVs and HVs) at a spatial scale of 500m and temporal scale of an hour, using transport demand modeling. The estimates are based on origin and destination trip pairs and the height of the planetary boundary layer (PBL). These estimates, performed for the years 2007 and 2012, depend also on intermediate variables as dilution rates (D) and surface particulate-matter concentrations (PM). Secondly, we assess the changes in CO2 vehicle emissions from the MRSP over the period 2007-2012 (4% year-1). Consequently, CO2 emission inventories merge trip-based surveys, traffic assignments and road network database with air pollution monitoring data. Despite the difference of the methodologies, we use a road link bottom up vehicle activity based approach, the assessed emissions agree with the State's Emission Inventory. This paper shows that the CO2 emissions from LDVs and HDVs in the MSP in 2007 and 2012 were 8,477 and 10,075 tCeq day-1 (58% LVs and 42% HVs), respectively. CO2 emissions from vehicles show spatial patterns consistent with passenger and freight transport trips and road network assignments. Temporal profiles (diurnal, weekly and monthly) were estimated using traffic counts and congestion surrogates. The profiles were compared with average road-site (Western of MSP) and background (Jaraguá Peak) CO2 measurements available for 2014. On-road measurements showed one peak associated to the morning peak hour of vehicles (437±45 ppm) and another night peak (435±49 ppm) related to the low PBL (313 m) and D (329 m2 h-1). From on-road measurements, background values (414±2 ppm) were subtracted to estimate excess CO2 (12±8 ppm) directly attributed to vehicles. The inventory reflects the relationships between traffic patterns and emissions, and the developed methodology could be used to evaluate the impacts of forthcoming urban transport and emission control policies. In the future, our estimates will be verified with ground measurements of CO2 concentrations over a bigger monitoring network in the MSP.

  11. The impact of a self-development coaching programme on medical and dental students' psychological health and academic performance: a randomised controlled trial.

    PubMed

    Aboalshamat, Khalid; Hou, Xiang-Yu; Strodl, Esben

    2015-08-19

    Psychological distress is well-documented worldwide among medical and dental students. Few studies have assessed the impact of self-development coaching programs on the students' psychological health. The aim of the study was to evaluate the effect of a self-development coaching programme on the psychological health and academic performance of preclinical medical and dental students at Umm Al-Qura University, Saudi Arabia. Four-hundred and twenty-two participants (n = 422, 20-22 years) fulfilled the study requirements and were invited into a parallel-randomised controlled trial that was partially blinded. Participants were stratified by faculty, gender, and academic year, and then randomised. A total of 156 students participated in the intervention group (IG) and 163 students participated in the control group (CG). The IG received the selfdevelopment programme, involving skills and strategies aimed to improve students' psychological health and academic performance, through a two-day workshop. Meanwhile, the CG attended an active placebo programme focussing on theoretical information that was delivered through a five-hour workshop. Both programmes were conducted by the same presenter during Week 1 of the second semester of the 2012-2013 academic year. Data were gathered immediately before (T1), one week after (T2) and five weeks (T3) after the intervention. Psychological health was measured using the Depression Anxiety Stress Scale (DASS-21), the General Self-Efficacy (GSE), and the Satisfaction With Life Scale (SWLS). Academic performance was measured using students' academic weighted grades (WG). Student cognitive and emotional perceptions of the intervention were measured using the Credibility/Expectancy Questionnaire (CEQ). Data from 317 students, who completed the follow ups, were analysed across the three time periods (IG, n = 155; CG, n = 162). The baseline variables and demographic data of the IG and CG were not significantly different. The IG showed short-term significant reductions in depression and anxiety in compared to CG from T1 to T2. The short-term changes in stress, GSE and SWLS of the IG were not significantly different from those of the CG. While both groups showed a significant change on most of the psychological variables from T1 to T3, no significant differences were found between the groups in this period. In addition, no significant difference was found in WG between the IG and CG after the intervention. No harms relevant to the intervention were reported. The investigated self-development coaching programme showed only a short-term improvement on depression and anxiety compared with an active control. There was no effect of the intervention on academic performance. ACTRN12614000896673.

  12. 7 CFR 51.1575 - U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of... Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade...

  13. 7 CFR 51.1576 - U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of... Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade...

  14. 7 CFR 51.1575 - U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of... Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade...

  15. 7 CFR 51.1576 - U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of... Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade...

  16. 7 CFR 51.1575 - U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of... Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade...

  17. 7 CFR 51.1576 - U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of... Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade...

  18. Costs along the service cascades for HIV testing and counselling and prevention of mother-to-child transmission

    PubMed Central

    Bautista-Arredondo, Sergio; Sosa-Rubí, Sandra G.; Opuni, Marjorie; Contreras-Loya, David; Kwan, Ada; Chaumont, Claire; Chompolola, Abson; Condo, Jeanine; Galárraga, Omar; Martinson, Neil; Masiye, Felix; Nsanzimana, Sabin; Ochoa-Moreno, Ivan; Wamai, Richard; Wang’ombe, Joseph

    2016-01-01

    Objective: We estimate facility-level average annual costs per client along the HIV testing and counselling (HTC) and prevention of mother-to-child transmission (PMTCT) service cascades. Design: Data collected covered the period 2011–2012 in 230 HTC and 212 PMTCT facilities in Kenya, Rwanda, South Africa, and Zambia. Methods: Input quantities and unit prices were collected, as were output data. Annual economic costs were estimated from the service providers’ perspective using micro-costing. Average annual costs per client in 2013 United States dollars (US$) were estimated along the service cascades. Results: For HTC, average cost per client tested ranged from US$5 (SD US$7) in Rwanda to US$31 (SD US$24) in South Africa, whereas average cost per client diagnosed as HIV-positive ranged from US$122 (SD US$119) in Zambia to US$1367 (SD US$2093) in Rwanda. For PMTCT, average cost per client tested ranged from US$18 (SD US$20) in Rwanda to US$89 (SD US$56) in South Africa; average cost per client diagnosed as HIV-positive ranged from US$567 (SD US$417) in Zambia to US$2021 (SD US$3210) in Rwanda; average cost per client on antiretroviral prophylaxis ranged from US$704 (SD US$610) in South Africa to US$2314 (SD US$3204) in Rwanda; and average cost per infant on nevirapine ranged from US$888 (SD US$884) in South Africa to US$2359 (SD US$3257) in Rwanda. Conclusion: We found important differences in unit costs along the HTC and PMTCT service cascades within and between countries suggesting that more efficient delivery of these services is possible. PMID:27753679

  19. Landuse Carbon Implications of a Drawdown of Ethanol Production and an Increase in Well-Managed Pastures

    NASA Astrophysics Data System (ADS)

    Hellwinckel, C. M.; Phillips, J.

    2011-12-01

    Over the past 10 years, commodity grain prices have doubled, and world commodity prices have reached their highest levels in over 30 years. The rise in prices culminated in the food price spikes of 2008 and 2011, where food riots erupted in 40 countries. Although studies have pointed to a number of factors leading to the increased food prices, the ethanol industry, whether deservingly or not, is seen as the major factor behind the price spikes. Several recent studies have contributed to the poor public opinion of ethanol by concluding that ethanol is neither a net energy source nor a net reducer of carbon emissions. The impact of these research reports combined with recent spikes in commodity prices has led to fierce political efforts to reduce or eliminate subsidies for ethanol. Opponents of ethanol subsidization won a significant battle with Congress recently voting to eliminate federal blender's tax credits and ethanol import tariffs. If another sharp spike in commodity prices occurs in the near future, some have speculated that ethanol production mandates could be scaled back or eliminated. In the span of less than three years the expected role of ethanol in the agricultural sector has gone from one of rapid growth and longevity, to one of which the societal benefits are being strongly questioned. In light of the rapidly changing expectations regarding the future of ethanol, we believe it is an appropriate time to evaluate the landuse and carbon implications of a scaling down of ethanol production and investigating permanent managed pasture as an alternative land use that could provide carbon benefits. Various USDA programs to promote conservation of, or conversion to, permanent pasture or grassland exist primarily based on the value of decreasing the potential for soil erosion as well as improving water quality. Although grazing systems have long been associated with land degradation in the arid and semi-arid west, new management approaches utilizing some form of rotational grazing are believed to reverse degradation and potentially lead to soil and pasture improvement if well managed, with implications for soil carbon storage. As the debate over societal subsidization of ethanol continues, the scientific communities should prepare for a potential drawdown of ethanol, and be aware of the potential land use impacts. An integrated biogeophysical socioeconomic model is used to evaluate three levels of potential reductions in ethanol production along with the possibility of conversion of non-profitable cropland to pasture management. The integrated model (POLYSYS) is driven by data on economics, terrestrial carbon dynamics, remotely-sensed land cover, and energy consumption. Preliminary results indicate that up to 10 million hectares of cropland could convert to pastureland, reducing agricultural land use emissions by nearly 10 teragrams carbon equivalent (TgCeq), a 36% decline in agricultural land use carbon equivalent emissions.

  20. Interagency Evaluation of the Section 1206 Global Train and Equip Program

    DTIC Science & Technology

    2009-08-31

    Capabilities, Joint Staff, U.S. Africa Command, U.S. Central Command, U.S Joint Forces Command, U.S. Pacific Command, U.S. Southern Command, U.S. Special...Intensity Conflict & Interdependent Capabilities; Commanders of U.S. Africa Command, U.S. Central Command, U.S. Joint Forces Command, U.S. Pacific... Central Command, commented that coordinating the Section 1206 project proposal with the partner nation prior to submission would inflate the

  1. 7 CFR 51.1576 - U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U...

  2. 7 CFR 51.1575 - U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U...

  3. 7 CFR 51.1576 - U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U...

  4. 7 CFR 51.1575 - U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U...

  5. Health care costs in US patients with and without a diagnosis of osteoarthritis

    PubMed Central

    Le, T Kim; Montejano, Leslie B; Cao, Zhun; Zhao, Yang; Ang, Dennis

    2012-01-01

    Background Osteoarthritis is a chronic and costly condition affecting 14% of adults in the US, and has a significant impact on patient quality of life. This retrospective cohort study compared direct health care utilization and costs between patients with osteoarthritis and a matched control group without osteoarthritis. Methods MarketScan® databases were used to identify adult patients with an osteoarthritis claim (ICD-9-CM, 715.xx) in 2007, and the date of first diagnosis served as the index. Patients were excluded if they did not have 12 months of continuous health care benefit prior to and following the index date, were aged <18 years, or lacked a second diagnosis code for osteoarthritis between 15 and 365 days pre-index or post-index. Osteoarthritis patients were matched 1:1 to patients without osteoarthritis for age group, gender, geographic region, health plan type, and Medicare eligibility. Multivariate analyses were conducted to assess for differences in utilization and costs, controlling for differences between cohorts. Results The study sample included 258,237 patients with osteoarthritis and 258,237 matched controls without osteoarthritis. Most patients were women and over 55 years of age. Patients with osteoarthritis had significantly higher pre-index rates of comorbidity than controls. Mean total adjusted direct costs for osteoarthritis patients were more than double those for the control group at US$18,435 (95% confidence interval [CI]: US$18,318–US$18,560) versus US$7494 (95% CI: US$7425–US$7557). Osteoarthritis patients incurred significantly higher inpatient costs at US$6668 (95% CI: US$6587–US$6744) versus US$1756 (95% CI: US$1717–US$1794), outpatient costs at US$7840 (95% CI: US$7786–US$7902) versus US$3675 (95% CI: US$3637–US$3711), and prescription drug costs at US$3213 (95% CI: US$3195–US$3233) versus US$2245 (95% CI: US$2229–US$2262) compared with the controls. Conclusion The direct health care costs of osteoarthritis patients were over two times higher than those of similar patients without the condition. The primary drivers of the cost difference were comorbidities and inpatient costs. PMID:22328832

  6. NREL: U.S. Life Cycle Inventory Database - Stakeholders

    Science.gov Websites

    Sylvatica U.S. Car Project (Ford, General Motors, and DaimlerChrysler) U.S. Department of Agriculture U.S Agriculture, Forest Service R&D U.S. Department of Energy U.S. Environmental Protection Agency U.S

  7. 23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Anchorage AK 3 Palmer. AK 2 AK 3 Fairbanks Milepost 1412 Delta Junction. AK 3 AK 1 Palmer AK 2 Fairbanks... Harbors. US 63 I-90 Rochester US 52 Rochester. US 63 MN 58 Red Wing WI State Line. US 71 IA State Line MN... State Line Red Wing MN US 2 W. of Ashland. US 141 US 41 Abrams US 8 Pembine. US 151 IA State Line...

  8. 23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Anchorage AK 3 Palmer. AK 2 AK 3 Fairbanks Milepost 1412 Delta Junction. AK 3 AK 1 Palmer AK 2 Fairbanks... Harbors. US 63 I-90 Rochester US 52 Rochester. US 63 MN 58 Red Wing WI State Line. US 71 IA State Line MN... State Line Red Wing MN US 2 W. of Ashland. US 141 US 41 Abrams US 8 Pembine. US 151 IA State Line...

  9. U.S. Korean Youth's Ideas and Experience of U.S. Education, U.S. Society, and U.S. History

    ERIC Educational Resources Information Center

    An, Sohyun

    2009-01-01

    Drawing on and conversing with the large body of research and literature on young people's historical understanding, Asian American education, transnational migration, and Korean American studies, this dissertation research explored contemporary U.S. Korean youth's ideas and experiences of U.S. education, U.S. society and U.S. history.…

  10. Fermilab Friends for Science Education | Join Us

    Science.gov Websites

    Fermilab Friends for Science Education FFSE Home About Us Join Us Support Us Contact Us Join Us photo Fermilab Friends for Science Education (FFSE) needs you now! More than ever our society and improving science (science, technology, engineering and mathematics) education. Your donation allows us to

  11. 77 FR 60603 - National Arts and Humanities Month, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... given us comfort and confidence, drawn us together, and called on us to strive for a more perfect Union... can resonate with us, challenge us, and teach us important lessons about ourselves and each other. At... all of us. They open dialogues between cultures and raise poignant questions about our world. They are...

  12. Contact Us

    Science.gov Websites

    Naval History Contact Us Command Addresses (SNDL) FAQ Leadership Secretary of the Navy Under Secretary Chiefs of Staff Defense.gov U.S. Army U.S. Air Force U.S. Marine Corps U.S. Coast Guard Naval History https://awards.navy.mil Naval Heritage And History Command http://www.history.navy.mil/about-us

  13. Surgeon-Performed Ultrasound-Guided Fine-Needle Aspiration Cytology (SP-US-FNAC) Shortens Time for Diagnosis of Thyroid Nodules.

    PubMed

    Gu, Wei Xiang; Tan, Chuen Seng; Ho, Thomas W T

    2014-06-01

    Ultrasound-guided fine-needle aspiration cytology (US-FNAC) of thyroid nodules is an important diagnostic procedure. In most hospitals, patients are referred to radiologists for US-FNAC, but this often results in a long waiting time before results are available. Surgeon-performed US-FNAC (SP-US-FNAC) during the initial patient consultation attempts to reduce the waiting time but it is not known whether this is as accurate as radiologist-performed US-FNAC (RP-US-FNAC). The aim of this study is to compare the clinical efficiency between SP-US-FNAC and RP-US-FNAC. A retrospective study was performed on patients from the Department of General Surgery, Tan Tock Seng Hospital (TTSH) who underwent an US-FNAC from August 2011 to May 2012. All cases of SP-US-FNAC were performed by a single surgeon. This study compared the rates of positive diagnoses achieved by SP-US-FNAC and RPUS- FNAC as well as the time interval to reach a cytological diagnosis by each group. A total of 40 cases of SP-US-FNAC and 72 cases of RP-US-FNAC were included in the study. SP-US-FNAC resulted in 28 (70%) positive diagnoses and 12 (30%) nondiagnoses while RP-US-FNAC resulted in 47 (65.3%) positive diagnoses and 25 (34.7%) non-diagnoses. These results were comparable (P=0.678). The median time taken to reach a cytological diagnosis was 1 working day for SP-US-FNAC and 29.5 working days for RP-US-FNAC resulting in a shorter interval to reaching a cytological diagnosis for SP-US-FNAC (P<0.001). In the workup of thyroid nodules, SP-US-FNAC is as accurate as RP-US-FNAC but significantly reduces the time taken to reach a cytological diagnosis. This leads to greater clinical efficiency in the management of patients with thyroid nodules, which in turn leads to other benefits such as decreased patient anxiety and increased patient satisfaction.

  14. Cost-efficacy of biologic therapies for psoriatic arthritis from the perspective of the Taiwanese healthcare system.

    PubMed

    Yang, Tsong-Shing; Chi, Ching-Chi; Wang, Shu-Hui; Lin, Jing-Chi; Lin, Ko-Ming

    2016-10-01

    Biologic therapies are more effective but more costly than conventional therapies in treating psoriatic arthritis. To evaluate the cost-efficacy of etanercept, adalimumab and golimumab therapies in treating active psoriatic arthritis in a Taiwanese setting. We conducted a meta-analysis of randomized placebo-controlled trials to calculate the incremental efficacy of etanercept, adalimumab and golimumab, respectively, in achieving Psoriatic Arthritis Response Criteria (PsARC) and a 20% improvement in the American College of Rheumatology score (ACR20). The base, best, and worst case incremental cost-effectiveness ratios (ICERs) for one subject to achieve PsARC and ACR20 were calculated. The annual ICER per PsARC responder were US$27 047 (best scenario US$16 619; worst scenario US$31 350), US$39 339 (best scenario US$31 846; worst scenario US$53 501) and US$27 085 (best scenario US$22 716; worst scenario US$33 534) for etanercept, adalimumab and golimumab, respectively. The annual ICER per ACR20 responder were US$27 588 (best scenario US$20 900; worst scenario US$41 800), US$39 339 (best scenario US$25 236; worst scenario US$83 595) and US$33 534 (best scenario US$27 616; worst scenario US$44 013) for etanercept, adalimumab and golimumab, respectively. In a Taiwanese setting, etanercept had the lowest annual costs per PsARC and ACR20 responder, while adalimumab had the highest annual costs per PsARC and ACR responder. © 2015 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

  15. ‘US Furr’ and ‘US Furr-ST’ Mandarin

    USDA-ARS?s Scientific Manuscript database

    This document marks the official release of ‘US Furr’, a hybrid of ‘Clementine’ x ‘Murcott’, and ‘US Furr-ST’, an irradiated variant of ‘US Furr’ with apparent field tolerance to citrus scab (causal agent Elsinoe fawcetti Bitanc. and Jenk.). The hybridization creating ‘US Furr’ and ultimately ‘US Fu...

  16. Ultrasound guidance system for prostate biopsy

    NASA Astrophysics Data System (ADS)

    Hummel, Johann; Kerschner, Reinhard; Kaar, Marcus; Birkfellner, Wolfgang; Figl, Michael

    2017-03-01

    We designed a guidance system for prostate biopsy based on PET/MR images and 3D ultrasound (US). With our proposed method common inter-modal MR-US (or CT-US in case of PET/CTs) registration can be replaced by an intra-modal 3D/3D-US/US registration and an optical tracking system (OTS). On the pre-operative site, a PET/MR calibration allows to link both hybrid modalities with an abdominal 3D-US. On the interventional site, another abdominal 3D US is taken to merge the pre-operative images with the real-time 3D-US via 3D/3D-US/US registration. Finally, the images of a tracked trans-rectal US probe can be displayed with the pre-operative images by overlay. For PET/MR image fusion we applied a point-to-point registration between PET and OTS and MR and OTS, respectively. 3D/3D-US/US registration was evaluated for images taken in supine and lateral patient position. To enable table shifts between PET/MR and US image acquisition a table calibration procedure is presented. We found fiducial registration errors of 0.9 mm and 2.8 mm, respectively, with respect to the MR and PET calibration. A target registration error between MR and 3D US amounted to 1.4 mm. The registration error for the 3D/3D-US/US registration was found to be 3.7 mm. Furthermore, we have shown that ultrasound is applicable in an MR environment.

  17. A cost comparison of more and less nutritious food choices in US supermarkets.

    PubMed

    Katz, David L; Doughty, Kim; Njike, Valentine; Treu, Judith A; Reynolds, Jesse; Walker, Jennifer; Smith, Erica; Katz, Catherine

    2011-09-01

    The present study directly compared prices of more and less nutritious foods within given categories in US supermarkets. Foods selected from six supermarkets in Jackson County were categorized using the five criteria of the Nutrition Detectives™ (ND) programme and an item-to-item cost comparison was made using posted prices. The nutritional quality of foods was distinguished using the clues of the ND nutrition education programme for elementary-school children and validated using the Overall Nutritional Quality Index. Supermarkets in Jackson County, MO, USA. Not applicable. The average price of the item for more nutritious foods did not differ significantly from that of less nutritious foods overall ($US 2·89 (sd $US 0·74) v. $US 2·85 (sd $0·68), P = 0·76). More nutritious breads cost more than less nutritious breads ($US 3·36 (sd $ US 0·28) v. $US 2·56 (sd $US 0·80, P = 0·03), whereas more nutritious cereals ($US 2·46 (sd $US 0·69) v. $US 3·50 (sd $US 0·30), P < 0·01) and cookies ($US 2·76 (sd $US 0·50) v. $US 3·40 (sd $US0·28), P < 0·01) cost less. Our findings indicate that it is possible to choose more nutritious foods within many common categories without spending more money and suggest that making small improvements in dietary choices does not invariably cost more.

  18. 22 CFR 127.4 - Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Authority of U.S. Immigration and Customs.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and.... (b) U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers have the...

  19. The U.S. Navy in the World (2001-2010): Context for U.S. Navy Capstone Strategies and Concepts

    DTIC Science & Technology

    2011-12-01

    Merchant Marine ocean- going shipbuilding each down to single digits US shipbuilding industry largely dependent on US Navy orders  Building few commercial...Merchant Marine ships 228 2000s: US shipbuilding industrial base 115 229 2000s: US government shipbuilding policies No US government ship construction ...Context for U.S. Navy Capstone Strategies and Concepts 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

  20. A navigation system for flexible endoscopes using abdominal 3D ultrasound

    NASA Astrophysics Data System (ADS)

    Hoffmann, R.; Kaar, M.; Bathia, Amon; Bathia, Amar; Lampret, A.; Birkfellner, W.; Hummel, J.; Figl, M.

    2014-09-01

    A navigation system for flexible endoscopes equipped with ultrasound (US) scan heads is presented. In contrast to similar systems, abdominal 3D-US is used for image fusion of the pre-interventional computed tomography (CT) to the endoscopic US. A 3D-US scan, tracked with an optical tracking system (OTS), is taken pre-operatively together with the CT scan. The CT is calibrated using the OTS, providing the transformation from CT to 3D-US. Immediately before intervention a 3D-US tracked with an electromagnetic tracking system (EMTS) is acquired and registered intra-modal to the preoperative 3D-US. The endoscopic US is calibrated using the EMTS and registered to the pre-operative CT by an intra-modal 3D-US/3D-US registration. Phantom studies showed a registration error for the US to CT registration of 5.1 mm ± 2.8 mm. 3D-US/3D-US registration of patient data gave an error of 4.1 mm compared to 2.8 mm with the phantom. From this we estimate an error on patient experiments of 5.6 mm.

  1. Ultrasound guidance for central venous catheter placement in Australasian emergency departments: potential barriers to more widespread use.

    PubMed

    Matera, Jakub T; Egerton-Warburton, Diana; Meek, Robert

    2010-12-01

    To survey Fellows of the Australasian College for Emergency Medicine (FACEMs) in order to describe current ultrasound (US) usage during central venous catheter (CVC) placement and to compare practice and opinions between FACEMs routinely using US and those not. Descriptive and analytical cross-sectional electronic survey of all FACEMs. Baseline variables including hospital type, US availability, frequency of CVC insertion, US usage and technique are presented descriptively. US practice and opinions on usage are compared between routine and non-routine users. Responses were obtained from 486 (42.4%) of 1146 FACEMs emailed. Whereas 88.5% of respondents had US available and 70% had done an US course, only 37% routinely used US for CVC placement. Completion of an US course and performance of >11 CVC per year were strongly associated with routine US use (odds ratio 10.0 [5.5-18.4] and 2.6 [1.7-3.9], respectively). Common barriers to more frequent US use were not having completed an US course (20%) and US-guided CVC placement taking too long (18%). Eighty-five per cent of FACEMs agreed that there should be ED access to US and US training but only 34% thought its use should be mandatory. We found that only 37% of FACEM respondents routinely used US to guide placement of CVCs and a number of barriers to more frequent use are identified. Practices and opinions regarding US use differed significantly between routine and non-routine users. © 2010 The Authors. EMA © 2010 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  2. 7 CFR 51.760 - Tolerances.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Bright, U.S. No. 1, U.S. No. 1 Golden, U.S. No. 1 Bronze, U.S. No. 1 Russet, U.S. No. 2 Bright, U.S. No... standards, means the point of origin of the shipment in the producing area or at port of loading for ship... further, that the entire lot averages within percentage specified. (2) U.S. No. 1 Golden. Not more than 30...

  3. 7 CFR 51.1151 - Tolerances.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., U.S. No. 1 Bright, U.S. No. 1, U.S. No. 1 Golden, U.S. No. 1 Bronze, U.S. No. 1 Russet, U.S. No. 2... in these standards, means the point of origin of the shipment in the producing area or at port of... specified. (2) U.S. No. 1 Golden. Not more than 30 percent of the fruit shall have in excess of one-third of...

  4. 7 CFR 51.1820 - Tolerances.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Bright, U.S. No. 1, U.S. No. 1 Golden, U.S. No. 1 Bronze, U.S. No. 1 Russet, U.S. No. 2 Bright, U.S. No... in these standards, means the point of origin of the shipment in the producing area or at port of... specified. (2) U.S. No. 1 Golden. Not more than 30 percent of the fruit shall have in excess of one-third of...

  5. AmeriFlux US-SCw Southern California Climate Gradient - Pinyon/Juniper Woodland

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goulden, Mike

    This is the AmeriFlux version of the carbon flux data for the site US-SCw Southern California Climate Gradient - Pinyon/Juniper Woodland. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a Pinyon Juniper woodland with trees that are at least 150 years old, and ephemeral herbaceous cover following winter or spring rains. The site has experienced repeated drought during the record and roughly 50% Pinyon mortality over the last decade. Amore » nearby tower site (US-SCc) burned in a 1994 wildfire; comparisons between US-SCw and US-SCc provide a measure of the effects of the 1994 on land-atmosphere exchange.« less

  6. Length of stay, hospitalization cost, and in-hospital mortality in US adult inpatients with immune thrombocytopenic purpura, 2006-2012.

    PubMed

    An, Ruopeng; Wang, Peizhong Peter

    2017-01-01

    In this study, we examined the length of stay, hospitalization cost, and risk of in-hospital mortality among US adult inpatients with immune thrombocytopenic purpura (ITP). We analyzed nationally representative data obtained from Nationwide/National Inpatient Sample database of discharges from 2006 to 2012. In the US, there were an estimated 296,870 (95% confidence interval [CI]: 284,831-308,909) patient discharges recorded for ITP from 2006 to 2012, during which ITP-related hospitalizations had increased steadily by nearly 30%. The average length of stay for an ITP-related hospitalization was found to be 6.02 days (95% CI: 5.93-6.10), which is 28% higher than that of the overall US discharge population (4.70 days, 95% CI: 4.66-4.74). The average cost of ITP-related hospitalizations was found to be US$16,594 (95% CI: US$16,257-US$16,931), which is 48% higher than that of the overall US discharge population (US$11,200; 95% CI: US$11,033-US$11,368). Gender- and age-adjusted mortality risk in inpatients with ITP was 22% (95% CI: 19%-24%) higher than that of the overall US discharge population. Across diagnosis related groups, length of stay for ITP-related hospitalizations was longest for septicemia (7.97 days, 95% CI: 7.55-8.39) and splenectomy (7.40 days, 95% CI: 6.94-7.86). Splenectomy (US$25,262; 95% CI: US$24,044-US$26,481) and septicemia (US$18,430; 95% CI: US$17,353-US$19,507) were associated with the highest cost of hospitalization. The prevalence of mortality in ITP-related hospitalizations was highest for septicemia (11.11%, 95% CI: 9.60%-12.63%) and intracranial hemorrhage (9.71%, 95% CI: 7.65%-11.77%). Inpatients with ITP had longer hospital stay, bore higher costs, and faced greater risk of mortality than the overall US discharge population.

  7. Prostate ultrasound--for urologists only?

    PubMed

    Frauscher, Ferdinand; Gradl, Johann; Pallwein, Leo

    2005-11-23

    The value of ultrasound (US) in the diagnosis of prostate cancer has dramatically increased in the past decade. This is mainly related to the increasing incidence of prostate cancer, the most common cancer in men and one of the most important causes of death from cancer in men. The value of conventional gray-scale US for prostate cancer detection has been extensively investigated, and has shown a low sensitivity and specificity. Therefore conventional gray-scale US is mainly used by urologists for guiding systematic prostate biopsies. With the development of new US techniques, such as color and power Doppler US, and the introduction of US contrast agents, the role of US for prostate cancer detection has dramatically changed. Advances in US techniques were introduced to further increase the value of US contrast agents. Although most of these developments in US techniques, which use the interaction of the contrast agent with the transmitted US waves, are very sensitive for the detection of microbubbles, they are mostly unexplored, in particular for prostate applications. Early reports of contrast-enhanced US investigations of blood flow of the prostate have shown that contrast-enhanced US adds important information to the conventional gray-scale US technique. Furthermore, elastography or 'strain imaging' seems to have great potential in prostate cancer detection. Since these new advances in US are very sophisticated and need a long learning curve, radiologists, who are overall better trained with these new US techniques, will play a more important role in prostate cancer diagnosis. Current trends show that these new US techniques may allow for targeted biopsies and therefore replace the current 'gold standard' for prostate cancer detection--the systematic biopsy. Consequently the use of these new US techniques for the detection and clinical staging of prostate cancer is promising. However, future clinical trials will be needed to determine if the promise of these new US advances of the prostate evolves into clinical application. International Cancer Imaging Society.

  8. Effect of Temperature on Growth and Sporulation of US-22, US-23, and US-24 Clonal Lineages of Phytophthora infestans and Implications for Late Blight Epidemiology.

    PubMed

    Seidl Johnson, Anna C; Frost, Kenneth E; Rouse, Douglas I; Gevens, Amanda J

    2015-04-01

    Epidemics of late blight, caused by Phytophthora infestans (Mont.) de Bary, have been studied by plant pathologists and regarded with great concern by potato and tomato growers since the Irish potato famine in the 1840s. P. infestans populations have continued to evolve, with unique clonal lineages arising which differ in pathogen fitness and pathogenicity, potentially impacting epidemiology. In 2012 and 2013, the US-23 clonal lineage predominated late blight epidemics in most U.S. potato and tomato production regions, including Wisconsin. This lineage was unknown prior to 2009. For isolates of three recently identified clonal lineages of P. infestans (US-22, US-23, and US-24), sporulation rates were experimentally determined on potato and tomato foliage and the effect of temperature on lesion growth rate on tomato was investigated. The US-22 and US-23 isolates had greater lesion growth rates on tomato than US-24 isolates. Sporulation rates for all isolates were greater on potato than tomato, and the US-23 isolates had greater sporulation rates on both tomato and potato than the US-22 and US-24 isolates. Experimentally determined correlates of fitness were input to the LATEBLIGHT model and epidemics were simulated using archived Wisconsin weather data from four growing seasons (2009 to 2012) to investigate the effect of isolates of these new lineages on late blight epidemiology. The fast lesion growth rates of US-22 and US-23 isolates resulted in severe epidemics in all years tested, particularly in 2011. The greater sporulation rates of P. infestans on potato resulted in simulated epidemics that progressed faster than epidemics simulated for tomato; the high sporulation rates of US-23 isolates resulted in simulated epidemics more severe than simulated epidemics of isolates of the US-22 and US-24 isolates and EC-1 clonal lineages on potato and tomato. Additionally, US-23 isolates consistently caused severe simulated epidemics when lesion growth rate and sporulation were input into the model singly or together. Sporangial size of the US-23 isolates was significantly smaller than that of US-22 and US-24 isolates, which may result in more efficient release of sporangia from the tomato or potato canopy. Our experimentally determined correlates of fitness and the simulated epidemics resulting from their incorporation into the LATEBLIGHT model suggest that US-23 isolates of P. infestans may have the greatest fitness among currently prevalent lineages and may be the most likely lineage to persist in the P. infestans population. The US-23 clonal lineage has been documented as the most prevalent lineage in recent years, indicating its overall fitness. In our work, US-23 had the highest epidemic potential among current genotypes. Given that epidemic potential is a component of fitness, this may, in part, explain the current predominance of the US-23 lineage.

  9. Memories of Reward and Nonreward Regulate the Extinction and Reacquisition of both Excitatory and Inhibitory Associations

    ERIC Educational Resources Information Center

    Capaldi, E. J.; Martins, Ana P. G.; Altman, Meaghan

    2009-01-01

    arrow]US associations also survived The memories of the unconditioned stimulus (US) and its absence (No US), symbolized as S[superscript R] and S[superscript N], respectively, may be retrieved on US or No US trials giving rise to four types of associations, S[superscript R][right arrow]US, S[superscript R][right arrow]No US, S[superscript N][right…

  10. CFS Forecast Verification

    Science.gov Websites

    history of Nino3.4 SST anomalies of individual forecasts Forecast anomalies Target season Nino SST Global SST Global Prec Global T2m US Prec US T2m US SM z200 NDJ 2004/2005 Nino SST Global SST Global Prec Global T2m US Prec US T2m US SM z200 DJF 2005 Nino SST Global SST Global Prec Global T2m US Prec US T2m

  11. What Causes POI?

    MedlinePlus

    Skip to main content US Department of Health and Human Services National Institutes of Health Directory Follow follow us on Facebook follow us on Twitter follow us on Pinterest follow us on YouTube ...

  12. Comparison of the application of B-mode and strain elastography ultrasound in the estimation of lymph node metastasis of papillary thyroid carcinoma based on a radiomics approach.

    PubMed

    Liu, Tongtong; Ge, Xifeng; Yu, Jinhua; Guo, Yi; Wang, Yuanyuan; Wang, Wenping; Cui, Ligang

    2018-06-21

    B-mode ultrasound (B-US) and strain elastography ultrasound (SE-US) images have a potential to distinguish thyroid tumor with different lymph node (LN) status. The purpose of our study is to investigate whether the application of multi-modality images including B-US and SE-US can improve the discriminability of thyroid tumor with LN metastasis based on a radiomics approach. Ultrasound (US) images including B-US and SE-US images of 75 papillary thyroid carcinoma (PTC) cases were retrospectively collected. A radiomics approach was developed in this study to estimate LNs status of PTC patients. The approach included image segmentation, quantitative feature extraction, feature selection and classification. Three feature sets were extracted from B-US, SE-US, and multi-modality containing B-US and SE-US. They were used to evaluate the contribution of different modalities. A total of 684 radiomics features have been extracted in our study. We used sparse representation coefficient-based feature selection method with 10-bootstrap to reduce the dimension of feature sets. Support vector machine with leave-one-out cross-validation was used to build the model for estimating LN status. Using features extracted from both B-US and SE-US, the radiomics-based model produced an area under the receiver operating characteristic curve (AUC) [Formula: see text] 0.90, accuracy (ACC) [Formula: see text] 0.85, sensitivity (SENS) [Formula: see text] 0.77 and specificity (SPEC) [Formula: see text] 0.88, which was better than using features extracted from B-US or SE-US separately. Multi-modality images provided more information in radiomics study. Combining use of B-US and SE-US could improve the LN metastasis estimation accuracy for PTC patients.

  13. Genomic organization of the canine herpesvirus US region.

    PubMed

    Haanes, E J; Tomlinson, C C

    1998-02-01

    Canine herpesvirus (CHV) is an alpha-herpesvirus of limited pathogenicity in healthy adult dogs and infectivity of the virus appears to be largely limited to cells of canine origin. CHV's low virulence and species specificity make it an attractive candidate for a recombinant vaccine vector to protect dogs against a variety of pathogens. As part of the analysis of the CHV genome, the authors determined the complete nucleotide sequence of the CHV US region as well as portions of the flanking inverted repeats. Seven full open reading frames (ORFs) encoding proteins larger than 100 amino acids were identified within, or partially within the CHV US: cUS2, cUS3, cUS4, cUS6, cUS7, cUS8 and cUS9; which are homologs of the herpes simplex virus type-1 US2; protein kinase; gG, gD, gI, gE; and US9 genes, respectively. An eighth ORF was identified in the inverted repeat region, cIR6, a homolog of the equine herpesvirus type-1 IR6 gene. The authors identified and mapped most of the major transcripts for the predicted CHV US ORFs by Northern analysis.

  14. Ultrasound-ultrasound image overlay fusion improves real-time control of radiofrequency ablation margin in the treatment of hepatocellular carcinoma.

    PubMed

    Minami, Yasunori; Minami, Tomohiro; Hagiwara, Satoru; Ida, Hiroshi; Ueshima, Kazuomi; Nishida, Naoshi; Murakami, Takamichi; Kudo, Masatoshi

    2018-05-01

    To assess the clinical feasibility of US-US image overlay fusion with evaluation of the ablative margin in radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). Fifty-three patients with 68 HCCs measuring 0.9-4.0 cm who underwent RFA guided by US-US overlay image fusion were included in this retrospective study. By an overlay of pre-/postoperative US, the tumor image could be projected onto the ablative hyperechoic zone. Therefore, the ablative margin three-dimensionally could be shown during the RFA procedure. US-US image overlay was compared to dynamic CT a few days after RFA for assessment of early treatment response. Accuracy of graded response was calculated, and the performance of US-US image overlay fusion was compared with that of CT using a Kappa agreement test. Technically effective ablation was achieved in a single session, and 59 HCCs (86.8 %) succeeded in obtaining a 5-mm margin on CT. The response with US-US image overlay correctly predicted early CT evaluation with an accuracy of 92.6 % (63/68) (k = 0.67; 95 % CI: 0.39-0.95). US-US image overlay fusion can be proposed as a feasible guidance in RFA with a safety margin and predicts early response of treatment assessment with high accuracy. • US-US image overlay fusion visualizes the ablative margin during RFA procedure. • Visualizing the margin during the procedure can prompt immediate complementary treatment. • US image fusion correlates with the results of early evaluation CT.

  15. Economic analysis of CDC's culture- and smear-based tuberculosis instructions for Filipino immigrants.

    PubMed

    Maskery, B; Posey, D L; Coleman, M S; Asis, R; Zhou, W; Painter, J A; Wingate, L T; Roque, M; Cetron, M S

    2018-04-01

    In 2007, the US Centers for Disease Control and Prevention (CDC) revised its tuberculosis (TB) technical instructions for panel physicians who administer mandatory medical examinations among US-bound immigrants. Many US-bound immigrants come from the Philippines, a high TB prevalence country. To quantify economic and health impacts of smear- vs. culture-based TB screening. Decision tree modeling was used to compare three Filipino screening programs: 1) no screening, 2) smear-based screening, and 3) culture-based screening. The model incorporated pre-departure TB screening results from Filipino panel physicians and CDC databases with post-arrival follow-up outcomes. Costs (2013 $US) were examined from societal, immigrant, US Public Health Department and hospitalization perspectives. With no screening, an annual cohort of 35 722 Filipino immigrants would include an estimated 450 TB patients with 264 hospitalizations, at a societal cost of US$9.90 million. Culture-based vs. smear-based screening would result in fewer imported cases (80.9 vs. 310.5), hospitalizations (19.7 vs. 68.1), and treatment costs (US$1.57 million vs. US$4.28 million). Societal screening costs, including US follow-up, were greater for culture-based screening (US$5.98 million) than for smear-based screening (US$3.38 million). Culture-based screening requirements increased immigrant costs by 61% (US$1.7 million), but reduced costs for the US Public Health Department (22%, US$750 000) and of hospitalization (70%, US$1 020 000). Culture-based screening reduced imported TB and US costs among Filipino immigrants.

  16. The cost of diabetes in Latin America and the Caribbean in 2015: Evidence for decision and policy makers.

    PubMed

    Barcelo, Alberto; Arredondo, Armando; Gordillo-Tobar, Amparo; Segovia, Johanna; Qiang, Anthony

    2017-12-01

    The financial implications of the increase in the prevalence of diabetes in middle-income countries represents one of the main challenges to health system financing and to the society as a whole. The objective of this study was to estimate the economic cost of diabetes in Latin America and the Caribbean (LAC) in 2015. The study used a prevalence-based approach to estimate the direct and indirect costs related to diabetes in 29 LAC countries in 2015. Direct costs included health care expenditures such as medications (insulin and oral hypoglycemic agents), tests, consultations, hospitalizations, emergency visits and treating complications. Two different scenarios (S1 and S2) were used to analyze direct cost. S1 assumed conservative estimates while S2 assumed broader coverage of medication and services. Indirect costs included lost resources due to premature mortality, temporary and permanent disabilities. In 2015 over 41 million adults (20 years of age and more) were estimated to have Diabetes Mellitus in LAC. The total indirect cost attributed to Diabetes was US$ 57.1 billion, of which US$ 27.5 billion was due to premature mortality, US$16.2 billion to permanent disability, and US$ 13.3 billion to temporary disability. The total direct cost was estimated between US$ 45 and US$ 66 billion, of which the highest estimated cost was due to treatment of complications (US$ 1 616 to US$ 26 billion). Other estimates indicated the cost of insulin between US$ 6 and US$ 11 billion; oral medication US$ 4 to US$ 6 billion; consultations between US$ 5 and US$ 6 billion; hospitalization US$ 10 billion; emergency visits US$ 1 billion; test and laboratory exams between US$ 1 and US$ 3 million. The total cost of diabetes in 2015 in LAC was estimated to be between US$ 102 and US$ 123 billion. On average, the annual cost of treating one case of diabetes mellitus (DM) in LAC was estimated between US$ 1088 and US$ 1818. Per capita National Health Expenditures averaged US$ 1061 in LAC. Diabetes represented a major economic burden to the countries of Latin America and the Caribbean in 2015. The estimates presented here are key information for decision-making that can be used in the formulation of policies and programs to achieve greater efficiency and effectiveness in the use of resources for diabetes prevention in the 29 countries of LAC.

  17. Shear Wave Elastography (SWE) for Monitoring of Treatment of Tendinopathies: A Double-blinded, Longitudinal Clinical Study.

    PubMed

    Dirrichs, Timm; Quack, Valentin; Gatz, Matthias; Tingart, Markus; Rath, Björn; Betsch, Marcel; Kuhl, Christiane K; Schrading, Simone

    2018-03-01

    We aimed to investigate the diagnostic accuracy with which shear wave elastography (SWE) can be used to monitor response to treatment of tendinopathies, and to compare it to conventional ultrasound (US)-imaging methods (B-mode US (B-US) and power Doppler US (PD-US)). A prospective Institutional Review Board-approved longitudinal study on 35 patients with 47 symptomatic tendons (17 Achilles-, 15 patellar-, and 15 humeral-epicondylar) who underwent standardized multimodal US and standardized clinical assessment before and after 6 months of treatment (tailored stretching exercise, sport break, and local Polidocanol) was carried out. All US studies were performed by radiologists blinded to the clinical symptoms on both tendon sides to avoid biased interpretations, by B-US, PD-US, and SWE, conducted in the same order, using a high-resolution linear 15 MHz probe (Aixplorer). Orthopedic surgeons who were in turn blinded to US imaging results used established orthopedic scores (Victorian Institute of Sports Assessment questionnaire for Achilles, Victorian Institute of Sports Assessment questionnaire for patellar tendons, and Disability Arm Shoulder Hand scoring system) to rate presence, degree, and possible resolution of symptoms. We analyzed the diagnostic accuracy with which the different US imaging methods were able to detect symptomatic tendons at baseline as well as treatment effects, with orthopedic scores serving as reference standard. B-US, PD-US, and SWE detected symptomatic tendons with a sensitivity of 66% (31 of 47), 72% (34 of 47), and 87.5% (41 of 47), respectively. Positive predictive value was 0.67 for B-US, 0.87 for PD-US, and 1 for SWE. After treatment, clinical scores improved in 68% (32 of 47) of tendons. Treatment effects were observable by B-US, PD-US, and SWE with a sensitivity of 3.1% (1 of 32), 28.1% (9 of 32), and 81.3% (26 of 32), respectively. B-US was false-positive in 68.8% (20 of 32), PD-US in 46.9% (15 of 32), and SWE in 12.5% (4 of 32) (SWE). Clinical scores and B-US, PD-US, and SWE findings correlated poorly (r = 0.24), moderately (r = 0.59), and strongly (r = 0.80). Unlike B-US or PD-US, SWE is able to depict processes associated with tendon healing and may be a useful tool to monitor treatment effects. Copyright © 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  18. The cost of diabetes in Latin America and the Caribbean in 2015: Evidence for decision and policy makers

    PubMed Central

    Barcelo, Alberto; Arredondo, Armando; Gordillo–Tobar, Amparo; Segovia, Johanna; Qiang, Anthony

    2017-01-01

    BACKGROUND The financial implications of the increase in the prevalence of diabetes in middle–income countries represents one of the main challenges to health system financing and to the society as a whole. The objective of this study was to estimate the economic cost of diabetes in Latin America and the Caribbean (LAC) in 2015. METHODS The study used a prevalence–based approach to estimate the direct and indirect costs related to diabetes in 29 LAC countries in 2015. Direct costs included health care expenditures such as medications (insulin and oral hypoglycemic agents), tests, consultations, hospitalizations, emergency visits and treating complications. Two different scenarios (S1 and S2) were used to analyze direct cost. S1 assumed conservative estimates while S2 assumed broader coverage of medication and services. Indirect costs included lost resources due to premature mortality, temporary and permanent disabilities. RESULTS In 2015 over 41 million adults (20 years of age and more) were estimated to have Diabetes Mellitus in LAC. The total indirect cost attributed to Diabetes was US$ 57.1 billion, of which US$ 27.5 billion was due to premature mortality, US$16.2 billion to permanent disability, and US$ 13.3 billion to temporary disability. The total direct cost was estimated between US$ 45 and US$ 66 billion, of which the highest estimated cost was due to treatment of complications (US$ 1 616 to US$ 26 billion). Other estimates indicated the cost of insulin between US$ 6 and US$ 11 billion; oral medication US$ 4 to US$ 6 billion; consultations between US$ 5 and US$ 6 billion; hospitalization US$ 10 billion; emergency visits US$ 1 billion; test and laboratory exams between US$ 1 and US$ 3 million. The total cost of diabetes in 2015 in LAC was estimated to be between US$ 102 and US$ 123 billion. On average, the annual cost of treating one case of diabetes mellitus (DM) in LAC was estimated between US$ 1088 and US$ 1818. Per capita National Health Expenditures averaged US$ 1061 in LAC. CONCLUSIONS Diabetes represented a major economic burden to the countries of Latin America and the Caribbean in 2015. The estimates presented here are key information for decision–making that can be used in the formulation of policies and programs to achieve greater efficiency and effectiveness in the use of resources for diabetes prevention in the 29 countries of LAC. PMID:29163935

  19. 78 FR 69864 - Privacy Act of 1974; Department of Homeland Security U.S. Citizenship and Immigration Services, U...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-21

    ... 1974; Department of Homeland Security U.S. Citizenship and Immigration Services, U.S. Immigration and... system of records notice titled, ``Department of Homeland Security U.S. Citizenship and Immigration... the Department of Homeland Security U.S. Citizenship and Immigration Services, U.S. Immigration and...

  20. Evaluating potential effects of widening US 64 on the black bear population of Alligator River National Wildlife Refuge, Dare County, North Carolina.

    DOT National Transportation Integrated Search

    2011-12-21

    This report summarizes research conducted along US Highway 64 (US 64) and US Highway 264 (US 264) in Alligator : River National Wildlife Refuge (ARNWR), Dare County, NC regarding the proposed expansion of US 64. The study site : included the areas ad...

  1. When congruence breeds preference: the influence of selective attention processes on evaluative conditioning.

    PubMed

    Blask, Katarina; Walther, Eva; Frings, Christian

    2017-09-01

    We investigated in two experiments whether selective attention processes modulate evaluative conditioning (EC). Based on the fact that the typical stimuli in an EC paradigm involve an affect-laden unconditioned stimulus (US) and a neutral conditioned stimulus (CS), we started from the assumption that learning might depend in part upon selective attention to the US. Attention to the US was manipulated by including a variant of the Eriksen flanker task in the EC paradigm. Similarly to the original Flanker paradigm, we implemented a target-distracter logic by introducing the CS as the task-relevant stimulus (i.e. the target) to which the participants had to respond and the US as a task-irrelevant distracter. Experiment 1 showed that CS-US congruence modulated EC if the CS had to be selected against the US. Specifically, EC was more pronounced for congruent CS-US pairs as compared to incongruent CS-US pairs. Experiment 2 disentangled CS-US congruence and CS-US compatibility and suggested that it is indeed CS-US stimulus congruence rather than CS-US response compatibility that modulates EC.

  2. Climate Information Needs for Financial Decision Making

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Higgins, Paul

    Climate Information Needs for Financial Decision Making (Final Report) This Department of Energy workshop award (grant #DE-SC0008480) provided primary support for the American Meteorological Society’s study on climate information needs for financial decision making. The goal of this study was to help advance societal decision making by examining the implications of climate variability and change on near-term financial investments. We explored four key topics: 1) the conditions and criteria that influence returns on investment of major financial decisions, 2) the climate sensitivity of financial decisions, 3) climate information needs of financial decision makers, and 4) potential new mechanisms to promotemore » collaboration between scientists and financial decision makers. Better understanding of these four topics will help scientists provide the most useful information and enable financial decision makers to use scientific information most effectively. As a result, this study will enable leaders in business and government to make well-informed choices that help maximize long-term economic success and social wellbeing in the United States The outcomes of the study include a workshop, which brought together leaders from the scientific and financial decision making communities, a publication of the study report, and a public briefing of the results to the policy community. In addition, we will present the results to the scientific community at the AMS Annual Meeting in February, 2014. The study results were covered well by the media including Bloomberg News and E&E News. Upon request, we also briefed the Office of Science Technology Policy (OSTP) and the Council on Environmental Quality (CEQ) on the outcomes. We presented the results to the policy community through a public briefing in December on Capitol Hill. The full report is publicly available at www.ametsoc.org/cin. Summary of Key Findings The United States invests roughly $1.5 trillion U.S. dollars (USD) in capital assets each year across the public and private sectors (Orszag 2008; United States Census Bureau 2013). Extreme weather events create and exacerbate risks to these financial investments by contributing to: • Direct physical impacts on the investments themselves • Degradation of critical supporting infrastructure • Changes in the availability of key natural resources • Changes to workforce availability or capacity • Changes in the customer base • Supply chain disruptions • Legal liability • Shifts in the regulatory environment • Reductions in credit ratings Even small changes in weather can impact operations in critical economic sectors. As a result, maximizing returns on financial investments depends on accurately understanding and effectively accounting for these risks. Climate variability and change can either exacerbate existing risks or cause new sources of risk to emerge. Managing these risks most effectively will depend on scientific advances and increases in the capacity of financial decision makers to use the scientific knowledge that results. Barriers to using climate information must also be overcome. This study proposes three predefined levels of certainty for communicating about weather and climate risks: 1) possible (i.e., unknown likelihood or less than 50% chance of occurrence), 2) probable (greater than 50% chance of occurrence), and 3) effectively certain (at least 95% chance of occurrence). For example, it is effectively certain that a change in climate will alter weather patterns. It is probable that climate warming will cause increases in the intensity of some extreme events. It is possible that climate change will cause major and widespread disruptions to key planetary life-support services. Key recommendations of this study: 1) Identify climate-related risks and opportunities for financial decision making. 2) Create a framework to translate scientific information in clear and actionable terms for financial decision makers. 3) Analyze existing climate assessments and translate projected impacts into possible, probable, and effectively certain impacts. 4) Improve climate projections with respect to precipitation (timing, amount, and intensity), extreme events, and tails of probability distributions (i.e., low-probability but high-consequence events). 5) Increase spatial resolution of climate projections in order to provide climate information at the scale most relevant to financial investments. 6) Improve projections of the societal consequences of climate impacts through integrated assessments of physical, natural, and social sciences. 7) Create a user-friendly information repository and portal that provides easy access to information relevant to financial decision making. 8) Create and maintain opportunities to bring together financial decision makers, scientists, and service providers. Near-term financial decisions have long-term implications for the United States’ social and economic well-being that depend, in part, on climate variability and change. Investments will be most successful, and will advance the interests of society most effectively, if they are grounded in the best available knowledge & understanding.« less

  3. Analysis of Transportation Options for Commercial Spent Fuel in the U.S.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kalinina, Elena; Busch, Ingrid Karin

    The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S.more » Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF)...« less

  4. Cost Analysis of Tuberculosis Diagnosis in Cambodia with and without Xpert® MTB/RIF for People Living with HIV/AIDS and People with Presumptive Multidrug-resistant Tuberculosis.

    PubMed

    Pallas, Sarah Wood; Courey, Marissa; Hy, Chhaily; Killam, Wm Perry; Warren, Dora; Moore, Brittany

    2018-06-04

    The Xpert ® MTB/RIF (Xpert) test has been shown to be effective and cost-effective for diagnosing tuberculosis (TB) under conditions with high HIV prevalence and HIV-TB co-infection but less is known about Xpert's cost in low HIV prevalence settings. Cambodia, a country with low HIV prevalence (0.7%), high TB burden, and low multidrug-resistant (MDR) TB burden (1.4% of new TB cases, 11% of retreatment cases) introduced Xpert into its TB diagnostic algorithms for people living with HIV (PLHIV) and people with presumptive MDR TB in 2012. The study objective was to estimate these algorithms' costs pre- and post-Xpert introduction in four provinces of Cambodia. Using a retrospective, ingredients-based microcosting approach, primary cost data on personnel, equipment, maintenance, supplies, and specimen transport were collected at four sites through observation, records review, and key informant consultations. Across the sample facilities, the cost per Xpert test was US$33.88-US$37.11, clinical exam cost US$1.22-US$1.84, chest X-ray cost US$2.02-US$2.14, fluorescent microscopy (FM) smear cost US$1.56-US$1.93, Ziehl-Neelsen (ZN) smear cost US$1.26, liquid culture test cost US$11.63-US$22.83, follow-on work-up for positive culture results and Mycobacterium tuberculosis complex (MTB) identification cost US$11.50-US$14.72, and drug susceptibility testing (DST) cost US$44.26. Specimen transport added US$1.39-US$5.21 per sample. Assuming clinician adherence to the algorithms and perfect test accuracy, the normative cost per patient correctly diagnosed under the post-Xpert algorithms would be US$25-US$29 more per PLHIV and US$34-US$37 more per person with presumptive MDR TB (US$41 more per PLHIV when accounting for variable test sensitivity and specificity). Xpert test unit costs could be reduced through lower cartridge prices, longer usable life of GeneXpert ® (Cepheid, USA) instruments, and increased test volumes; however, epidemiological and test eligibility conditions in Cambodia limit the number of specimens received at laboratories, leading to sub-optimal utilization of current instruments. Improvements to patient referral and specimen transport could increase test volumes and reduce Xpert test unit costs in this setting.

  5. AmeriFlux US-SCd Southern California Climate Gradient - Sonoran Desert

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goulden, Mike

    This is the AmeriFlux version of the carbon flux data for the site US-SCd Southern California Climate Gradient - Sonoran Desert. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a low desert site in Southern California's rain shadow; the climate is extremely dry and hot. The site has experience repeated droughts, with negligible rainfall during several years of the record.

  6. Disparities in Health Care Coverage Among U.S. Born and Mexican/Central American Born Labor Workers in the U.S.

    PubMed

    Hammig, Bart; Henry, Jean; Davis, Donna

    2018-01-31

    We examined health insurance coverage among U.S. and Mexican/Central American (M/CA) born labor workers living in the U.S. Using data from the 2010-2015 National Health Interview Survey, we employed logistic regression models to examine health insurance coverage and covariates among U.S. and M/CA born labor workers. Prevalence ratios between U.S. and M/CA born workers were also obtained. U.S. born workers had double the prevalence of insurance coverage. Regarding private insurance coverage, U.S. born workers had a higher prevalence of coverage compared to their M/CA born counterparts. Among foreign born workers with U.S. citizenship, the odds of having insurance coverage was greater than that of noncitizens. Additionally, those who had lived in the U.S. for 10 or more years had higher odds of having health insurance coverage. Disparities in health care coverage exist between U.S. born and foreign born labor workers.

  7. Genomic analyses of dominant U.S. clonal lineages of Phytophthora infestans reveals a shared common ancestry for clonal lineages US11 and US18 and a lack of recently shared ancestry among all other U.S. lineages

    USDA-ARS?s Scientific Manuscript database

    The populations of the potato and tomato late blight pathogen, Phytophthora infestans, in the US are well known for emerging repeatedly as novel clonal lineages. These successions of dominant clones have historically been named US1-US24, in order of appearance, since their first characterization usi...

  8. U.S. hardwood product exports, hardwood exports to Korea, hardwood resource situation, and the future of U.S. exports to Korea

    Treesearch

    Philip A. Araman

    1991-01-01

    The exerpts from this seminar are intended to give an overview of U.S. hardwood exports, hardwood exports to Korea, the hardwood resource situation, and the future of U.S. hardwood exports to Korea. It includes 1) some basic information about total U.S. hardwood exports and products, 2) information on hardwood exports to Korea from the U.S., 3) U.S. hardwood resources...

  9. Materials Chemistry of Nanoultrasonic Biomedicine.

    PubMed

    Tang, Hailin; Zheng, Yuanyi; Chen, Yu

    2017-03-01

    As a special cross-disciplinary research frontier, nanoultrasonic biomedicine refers to the design and synthesis of nanomaterials to solve some critical issues of ultrasound (US)-based biomedicine. The concept of nanoultrasonic biomedicine can also overcome the drawbacks of traditional microbubbles and promote the generation of novel US-based contrast agents or synergistic agents for US theranostics. Here, we discuss the recent developments of material chemistry in advancing the nanoultrasonic biomedicine for diverse US-based bio-applications. We initially introduce the design principles of novel nanoplatforms for serving the nanoultrasonic biomedicine, from the viewpoint of synthetic material chemistry. Based on these principles and diverse US-based bio-application backgrounds, the representative proof-of-concept paradigms on this topic are clarified in detail, including nanodroplet vaporization for intelligent/responsive US imaging, multifunctional nano-contrast agents for US-based multi-modality imaging, activatable synergistic agents for US-based therapy, US-triggered on-demand drug releasing, US-enhanced gene transfection, US-based synergistic therapy on combating the cancer and potential toxicity issue of screening various nanosystems suitable for nanoultrasonic biomedicine. It is highly expected that this novel nanoultrasonic biomedicine and corresponding high performance in US imaging and therapy can significantly promote the generation of new sub-discipline of US-based biomedicine by rationally integrating material chemistry and theranostic nanomedicine with clinical US-based biomedicine. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. What Can I Do to Promote a Healthy Pregnancy?

    MedlinePlus

    Skip to main content US Department of Health and Human Services National Institutes of Health Directory Follow follow us on Facebook follow us on Twitter follow us on Pinterest follow us on YouTube ...

  11. 15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...

  12. 15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...

  13. 15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...

  14. 15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...

  15. 15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...

  16. Work with Us | Transportation Research | NREL

    Science.gov Websites

    Work with Us Work with Us NREL offers industry, academia, and government agencies opportunities to work with us and leverage our transportation research and capabilities. Photo of two men standing in more Contact Us To learn more about partnering with NREL on research projects, contact us. Partner with

  17. Work with Us | Integrated Energy Solutions | NREL

    Science.gov Websites

    Work with Us Work with Us NREL offers industry, academia, and government agencies opportunities to work with us and leverage our research, facilities, and expertise. Contact Us Photo of Adam Warren with Us We're making an impact on advancing integrated energy solutions in the United States and abroad

  18. Fermilab Friends for Science Education | Contact Us

    Science.gov Websites

    Fermilab Friends for Science Education FFSE Home About Us Join Us Support Us Contact Us Contact Us Science Education P.O Box 500, MS 777 Batavia, IL 60510-5011 (630) 840-3094 * fax: (630) 840-2500 E-mail : Membership Send all other communications to: Susan Dahl, President Fermilab Friends for Science Education Box

  19. 75 FR 14135 - U.S. Travel And Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel And Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open meeting. SUMMARY: The U.S. Travel and Tourism Advisory...

  20. 75 FR 39496 - U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-09

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open meeting. SUMMARY: The U.S. Travel and Tourism Advisory...

  1. Are the U.S. territories lagging behind in diabetes care practices?

    PubMed

    Ogilvie, Rachel P; Patel, Shivani A; Narayan, K M Venkat; Mehta, Neil K

    2018-05-09

    Although U.S. territories fall within the mandate outlined by Healthy People 2020, they remain neglected in diabetes care research. We compared the prevalence and secular trends of four recommended diabetes care practices in the U.S. territories of Guam, Puerto Rico, and the U.S. Virgin Islands to the 50 United States and D.C. ("U.S. States") in 2001-2015. Data were from 390,268 adult participants with self-reported physician diagnosed diabetes in the Behavioral Risk Factor Surveillance System. Diabetes care practices included biannual HbA1c tests, attendance of diabetes education classes, daily self-monitoring of blood glucose, and receipt of annual foot examination. Practices were compared by U.S. territory and between territories and U.S. states. Multivariable models accounted for age, sex, education, and year. Of adults with diagnosed diabetes, 7% to 11% in the U.S. territories engaged in all four recommended diabetes care practices compared with 25% for those, on average, in U.S. states. Relative to the U.S. states, on average, the proportion achieving biannual HbA1c testing was lower in Guam and the U.S. Virgin Islands (45.6% and 44.9% vs. 62.2%), while annual foot examinations were lower in Puerto Rico (45.9% vs 66.1% in the U.S. states). Diabetes education and daily glucose self-monitoring were lower in all three territories. U.S. territories lag behind U.S. states in diabetes care practices. Policies aimed at improving diabetes care practices are needed in the U.S. territories to achieve Healthy People 2020 goals and attain parity with U.S. states. Copyright © 2018 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

  2. Sensitivity and specificity of linear array intraoperative ultrasound in glioblastoma surgery: a comparative study with high field intraoperative MRI and conventional sector array ultrasound.

    PubMed

    Coburger, Jan; Scheuerle, Angelika; Kapapa, Thomas; Engelke, Jens; Thal, Dietmar Rudolf; Wirtz, Christian R; König, Ralph

    2015-07-01

    Linear array intraoperative ultrasound (lioUS) is an emerging technology for intracranial use. We evaluated sensitivity and specificity of lioUS to detect residual tumor in patients harboring a glioblastoma. After near total resection in 20 patients, residual tumor detection using lioUS, conventional intraoperative ultrasound (cioUS), and gadopentetic-diethylenetriamine penta-acetic acid (Gd-DTPA)-enhanced intraoperative MRI (iMRI) were compared. Sensitivity and specificity were calculated based on 68 navigated biopsies. Receiver operator characteristic (ROC) curves and correlation with histopathological findings of each imaging modality were calculated. Additionally, results were evaluated in the subgroup of recurrent disease (23 biopsies in 8 patients). Sensitivity of lioUS (76 %) was significantly higher compared with iMRI (55 %) and cioUS (24 %). Specificity of lioUS (58 %) was significantly lower than in cioUS (96 %), while there was no significant difference to iMRI (74 %). All imaging modalities correlated significantly with histopathological findings. In the subgroup of recurrent disease, sensitivity and specificity decreased in all modalities. However, cioUS showed significant lower values than iMRI and lioUS. In ROC curves, lioUS showed a higher area und the curve (AUC) in comparison with iMRI and cioUS. We found similar results in the subgroup of recurrent disease. Tumor detection using a lioUS is significantly superior to cioUS. Overall test performance in lioUS is comparable with results of iMRI. While, the latter has a higher specificity and a significantly lower sensitivity in comparison with lioUS.

  3. Polycystic ovarian disease: contribution of vaginal endosonography and reassessment of ultrasonic diagnosis.

    PubMed

    Ardaens, Y; Robert, Y; Lemaitre, L; Fossati, P; Dewailly, D

    1991-06-01

    We evaluated the superiority of vaginal ultrasonography (US) on the abdominal US for the diagnosis of polycystic ovarian disease (PCOD). The US pattern of ovaries was prospectively investigated by abdominal US and, whenever possible, by vaginal US. Primary care, institutional. One hundred forty-four women in whom PCOD was suspected on endocrine grounds and 62 other patients presenting with primary hyperprolactinemia (n = 23) or hypothalamic anovulation (n = 39). Vaginal US allowed a better analysis of the ovarian stroma. The external ovarian features of PCOD were observed by both routes in less than one third of the 144 patients with PCOD. The internal ovarian features of PCOD were much more frequently observed by vaginal US than by abdominal US (polycystic pattern: 66.7% versus 38.1%, P less than 0.05; increased ovarian stroma: 57.1% versus 4.8%, P less than 0.001). In the 62 patients without PCOD, US features of PCOD were observed in less than 10% of them, except for the uterine width/ovarian length ratio less than 1 and the polycystic pattern (abdominal US: 17% and 34%; vaginal US: 11% and 50%, respectively). An increased ovarian stroma seems to be the most sensitive and specific US sign of PCOD, providing that it can be investigated by vaginal US.

  4. Characterizing tuberculosis genotype clusters along the United States-Mexico border.

    PubMed

    Baker, B J; Moonan, P K

    2014-03-01

    We examined the growth of tuberculosis (TB) genotype clusters during 2005-2010 in the United States, categorized by country of origin and ethnicity of the index case and geographic proximity to the US-Mexico border at the time of TB diagnosis. Nationwide, 38.9% of cases subsequent to Mexico-born index cases were US-born. Among clusters following US-born Hispanic and US-born non-Hispanic index cases, respectively 29.2% and 5.3% of subsequent cluster members were Mexico-born. In border areas, the majority of subsequent cases were Mexico-born following US-born Hispanic (56.4%) and US-born non-Hispanic (55.6%) index cases. These findings suggest that TB transmission commonly occurs between US-born and Mexico-born persons. Along the US-Mexico border, prioritizing TB genotype clusters following US-born index cases for investigation may prevent subsequent cases among both US-born and Mexico-born persons.

  5. Exploring the Association of Homicides in Northern Mexico and Healthcare Access for US Residents.

    PubMed

    Geissler, Kimberley H; Becker, Charles; Stearns, Sally C; Thirumurthy, Harsha; Holmes, George M

    2015-08-01

    Many legal residents in the United States (US)-Mexico border region cross from the US into Mexico for medical treatment and pharmaceuticals. We analyzed whether recent increases in homicides in Mexico are associated with reduced healthcare access for US border residents. We used data on healthcare access, legal entries to the US from Mexico, and Mexican homicide rates (2002-2010). Poisson regression models estimated associations between homicide rates and total legal US entries. Multivariate difference-in-difference linear probability models evaluated associations between Mexican homicide rates and self-reported measures of healthcare access for US residents. Increased homicide rates were associated with decreased legal entries to the US from Mexico. Contrary to expectations, homicides did not have significant associations with healthcare access measures for legal residents in US border counties. Despite a decrease in border crossings, increased violence in Mexico did not appear to negatively affect healthcare access for US border residents.

  6. Adaptation and application of multivariate AMBI (M-AMBI) in US coastal waters.

    PubMed

    Pelletier, Marguerite C; Gillett, David J; Hamilton, Anna; Grayson, Treda; Hansen, Virginia; Leppo, Erik W; Weisberg, Stephan B; Borja, Angel

    2018-06-01

    The multivariate AMBI (M-AMBI) is an extension of the AZTI Marine Biotic Index (AMBI) that has been used extensively in Europe, but not in the United States. In a previous study, we adapted AMBI for use in US coastal waters (US AMBI), but saw biases in salinity and score distribution when compared to locally calibrated indices. In this study we modified M-AMBI for US waters and compared its performance to that of US AMBI. Index performance was evaluated in three ways: 1) concordance with local indices presently being used as management tools in three geographic regions of US coastal waters, 2) classification accuracy for sites defined a priori as good or bad and 3) insensitivity to natural environmental gradients. US M-AMBI was highly correlated with all three local indices and removed the compression in response seen in moderately disturbed sites with US AMBI. US M-AMBI and US AMBI did a similar job correctly classifying sites as good or bad in local validation datasets (83 to 100% accuracy vs. 84 to 95%, respectively). US M-AMBI also removed the salinity bias of US AMBI so that lower salinity sites were not more likely to be incorrectly classified as impaired. The US M-AMBI appears to be an acceptable index for comparing condition across broad-scales such as estuarine and coastal waters surveyed by the US EPA's National Coastal Condition Assessment, and may be applicable to areas of the US coast that do not have a locally derived benthic index.

  7. Cesarean birth in the border region: a descriptive analysis based on US Hispanic and Mexican birth certificates.

    PubMed

    McDonald, Jill A; Mojarro Davila, Octavio; Sutton, Paul D; Ventura, Stephanie J

    2015-01-01

    Cesarean birth (CB) is more prevalent in the US-Mexico border region than among all US Hispanics. Comparable data from US and Mexican birth certificates can be used to compare prevalence and identify risk factors on either side of the border. Using 2009 US and Mexican birth certificates, we compared the characteristics of US Hispanic and Mexican CBs in six geographic subgroups: US and Mexican border counties/municipios, US and Mexican non-border counties/municipios and the US and Mexico overall. We also explored cesarean prevalence over time. During 2000-2009, CB rates increased from 22.1 to 31.6 % among US Hispanics and from 25.9 to 37.9 % among Hispanics in the US border region. 2009 rates were 44.5 % in Mexico and 43.1 % in the Mexican border region. In both countries, CB rates were similar for primiparas and multiparas. Higher education, being married and parity >4 were associated with CB in Mexico; being married was associated in the US. Hispanic rates were higher in the US border than non-border region for all age groups. Along the border, cesarean rates for Hispanics were highest in Texas (43.5 %) and neighboring Tamaulipas (49.8 %). Higher cesarean prevalence in Mexico than in US Hispanics, while unexplained, is consistent with high prevalence in some Latin American countries. Higher cesarean prevalence among Hispanics in the US border region than among Hispanics nationwide cannot be explained by maternal age or parity. Medical indications are also unlikely to explain such high rates, which are undesirable for mothers and infants.

  8. A Pivotal Study of Optoacoustic Imaging to Diagnose Benign and Malignant Breast Masses: A New Evaluation Tool for Radiologists.

    PubMed

    Neuschler, Erin I; Butler, Reni; Young, Catherine A; Barke, Lora D; Bertrand, Margaret L; Böhm-Vélez, Marcela; Destounis, Stamatia; Donlan, Pamela; Grobmyer, Stephen R; Katzen, Janine; Kist, Kenneth A; Lavin, Philip T; Makariou, Erini V; Parris, Tchaiko M; Schilling, Kathy J; Tucker, F Lee; Dogan, Basak E

    2018-05-01

    Purpose To compare the diagnostic utility of an investigational optoacoustic imaging device that fuses laser optical imaging (OA) with grayscale ultrasonography (US) to grayscale US alone in differentiating benign and malignant breast masses. Materials and Methods This prospective, 16-site study of 2105 women (study period: 12/21/2012 to 9/9/2015) compared Breast Imaging Reporting and Data System (BI-RADS) categories assigned by seven blinded independent readers to benign and malignant breast masses using OA/US versus US alone. BI-RADS 3, 4, or 5 masses assessed at diagnostic US with biopsy-proven histologic findings and BI-RADS 3 masses stable at 12 months were eligible. Independent readers reviewed US images obtained with the OA/US device, assigned a probability of malignancy (POM) and BI-RADS category, and locked results. The same independent readers then reviewed OA/US images, scored OA features, and assigned OA/US POM and a BI-RADS category. Specificity and sensitivity were calculated for US and OA/US. Benign and malignant mass upgrade and downgrade rates, positive and negative predictive values, and positive and negative likelihood ratios were compared. Results Of 2105 consented subjects with 2191 masses, 100 subjects (103 masses) were analyzed separately as a training population and excluded. An additional 202 subjects (210 masses) were excluded due to technical failures or incomplete imaging, 72 subjects (78 masses) due to protocol deviations, and 41 subjects (43 masses) due to high-risk histologic results. Of 1690 subjects with 1757 masses (1079 [61.4%] benign and 678 [38.6%] malignant masses), OA/US downgraded 40.8% (3078/7535) of benign mass reads, with a specificity of 43.0% (3242/7538, 99% confidence interval [CI]: 40.4%, 45.7%) for OA/US versus 28.1% (2120/7543, 99% CI: 25.8%, 30.5%) for the internal US of the OA/US device. OA/US exceeded US in specificity by 14.9% (P < .0001; 99% CI: 12.9, 16.9%). Sensitivity for biopsied malignant masses was 96.0% (4553/4745, 99% CI: 94.5%, 97.0%) for OA/US and 98.6% (4680/4746, 99% CI: 97.8%, 99.1%) for US (P < .0001). The negative likelihood ratio of 0.094 for OA/US indicates a negative examination can reduce a maximum US-assigned pretest probability of 17.8% (low BI-RADS 4B) to a posttest probability of 2% (BI-RADS 3). Conclusion OA/US increases the specificity of breast mass assessment compared with the device internal grayscale US alone. Online supplemental material is available for this article. © RSNA, 2017.

  9. Taste and Smell Disorders

    MedlinePlus

    ... give us great pleasure. Taste helps us enjoy food and beverages. Smell lets us enjoy the scents and fragrances like roses or coffee. Taste and smell also protect us, letting us know when food has gone bad or when there is a ...

  10. Fermilab Friends for Science Education | Board Tools

    Science.gov Websites

    Fermilab Friends for Science Education FFSE Home About Us Join Us Support Us Contact Us Board Tools Testimonials Our Donors Board of Directors Board Tools Calendar Join Us Donate Now Get FermiGear! Education

  11. 22 CFR 127.4 - Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. 127.4 Section 127.4 Foreign Relations DEPARTMENT.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and...

  12. 22 CFR 127.4 - Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. 127.4 Section 127.4 Foreign Relations DEPARTMENT.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and...

  13. 22 CFR 127.4 - Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. 127.4 Section 127.4 Foreign Relations DEPARTMENT.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and...

  14. 78 FR 11141 - BE-577: Quarterly Survey of U.S. Direct Investment Abroad- Direct Transactions of U.S. Reporter...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... BE-577: Quarterly Survey of U.S. Direct Investment Abroad-- Direct Transactions of U.S. Reporter With... that it is conducting the mandatory surveys titled BE-577, Quarterly Survey of U.S. Direct Investment Abroad--Direct Transactions of U.S. Reporter with Foreign Affiliate. This survey is authorized by the...

  15. 7 CFR 51.685 - U.S. Combination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Combination. 51.685 Section 51.685 Agriculture....685 U.S. Combination. “U.S. Combination” consists of a combination of U.S. No. 1 and U.S. No. 2 oranges: Provided, That the number of U.S. No. 2 fruits specified in § 51.689, Tables I and II, are not...

  16. 75 FR 80039 - U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... agenda for an open meeting of the U.S. Travel and Tourism Advisory Board (Board). The agenda may change...

  17. 76 FR 53666 - U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-29

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... agenda for an open meeting of the U.S. Travel and Tourism Advisory Board (Board). The agenda may change...

  18. 76 FR 21703 - U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... agenda for an open meeting of the U.S. Travel and Tourism Advisory Board (Board). The agenda may change...

  19. 17 CFR 151.2 - Core Referenced Futures Contracts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...); (vi) Chicago Board of Trade Wheat (W); (vii) ICE Futures U.S. Cotton No. 2 (CT); (viii) Kansas City... Rice (RR); (vi) ICE Futures U.S. Cocoa (CC); (vii) ICE Futures U.S. Coffee C (KC); (viii) ICE Futures U.S. FCOJ-A(OJ); (ix) ICE Futures U.S. Sugar No. 11 (SB); and (x) ICE Futures U.S. Sugar No. 16 (SF...

  20. 17 CFR 151.2 - Core Referenced Futures Contracts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...); (vi) Chicago Board of Trade Wheat (W); (vii) ICE Futures U.S. Cotton No. 2 (CT); (viii) Kansas City... Rice (RR); (vi) ICE Futures U.S. Cocoa (CC); (vii) ICE Futures U.S. Coffee C (KC); (viii) ICE Futures U.S. FCOJ-A(OJ); (ix) ICE Futures U.S. Sugar No. 11 (SB); and (x) ICE Futures U.S. Sugar No. 16 (SF...

  1. 17 CFR 151.2 - Core Referenced Futures Contracts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...); (vi) Chicago Board of Trade Wheat (W); (vii) ICE Futures U.S. Cotton No. 2 (CT); (viii) Kansas City... Rice (RR); (vi) ICE Futures U.S. Cocoa (CC); (vii) ICE Futures U.S. Coffee C (KC); (viii) ICE Futures U.S. FCOJ-A(OJ); (ix) ICE Futures U.S. Sugar No. 11 (SB); and (x) ICE Futures U.S. Sugar No. 16 (SF...

  2. AmeriFlux US-SCf Southern California Climate Gradient - Oak/Pine Forest

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goulden, Mike

    This is the AmeriFlux version of the carbon flux data for the site US-SCf Southern California Climate Gradient - Oak/Pine Forest. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a mixed oak/pine forest. The site experiences episodic severe drought and mortality, and has also experienced occasional logging and wildfire. Drought and mortality was especially severe in the early 2000s.

  3. International perceptions of US nuclear policy.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stanley, Elizabeth A.

    The report presents a summary of international perceptions and beliefs about US nuclear policy, focusing on four countries--China, Iran, Pakistan and Germany--chosen because they span the spectrum of states with which the United States has relationships. A paradox is pointed out: that although the goal of US nuclear policy is to make the United States and its allies safer through a policy of deterrence, international perceptions of US nuclear policy may actually be making the US less safe by eroding its soft power and global leadership position. Broadly held perceptions include a pattern of US hypocrisy and double standards--one setmore » for the US and its allies, and another set for all others. Importantly, the US nuclear posture is not seen in a vacuum, but as one piece of the United States behavior on the world stage. Because of this, the potential direct side effects of any negative international perceptions of US nuclear policy can be somewhat mitigated, dependent on other US policies and actions. The more indirect and long term relation of US nuclear policy to US international reputation and soft power, however, matters immensely to successful multilateral and proactive engagement on other pressing global issues.« less

  4. Site Area Boundaries

    EPA Pesticide Factsheets

    This dataset consists of site boundaries from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different times and were combined into one region-wide layer. Thus far the sources include:1. California Gulch (Irrigated Meadows) - ESAT Contractor.2. Manning Canyon - U.S. EPA Region 8; ESAT Contractor.3. Rapid City Small Arms Range - U.S. EPA Region 8; ESAT Contractor.4. Animas River/Cement Creek - U.S. EPA Region 8; ESAT Contractor.5. Monticello Mill Tailings (USDOE) - USDOE; ESAT Contractor.6. Pinon Canyon - USDOD.7. Rock Flats Industrial Park - U.S. EPA Region 8.8. Bountiful/Woods Cross - U.S. EPA Region 8.9. Lincoln Park - U.S. EPA Region 8.10. Marshall Landfill - U.S. EPA Region 8.11. U.S. Magnesium - Pacific Western Technologies Inc.

  5. Construction of Silica-Based Micro/Nanoplatforms for Ultrasound Theranostic Biomedicine.

    PubMed

    Zhou, Yang; Han, Xiaoxia; Jing, Xiangxiang; Chen, Yu

    2017-09-01

    Ultrasound (US)-based biomedicine has been extensively explored for its applications in both diagnostic imaging and disease therapy. The fast development of theranostic nanomedicine significantly promotes the development of US-based biomedicine. This progress report summarizes and discusses the recent developments of rational design and fabrication of silica-based micro/nanoparticles for versatile US-based biomedical applications. The synthetic strategies and surface-engineering approaches of silica-based micro/nanoparticles are initially discussed, followed by detailed introduction on their US-based theranostic applications. They have been extensively explored in contrast-enhanced US imaging, US-based multi-modality imaging, synergistic high-intensity focused US (HIFU) ablation, sonosensitizer-enhanced sonodynamic therapy (SDT), as well as US-triggered chemotherapy. Their biological effects and biosafety have been briefly discussed to guarantee further clinical translation. Based on the high biocompatibility, versatile composition/structure and high performance in US-based theranostic biomedicine, these silica-based theranostic agents are expected to pave a new way for achieving efficient US-based theranostics of disease by taking the specific advantages of material science, nanotechnology and US-based biomedicine. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Relevance of Global Health Security to the US Export Economy.

    PubMed

    Cassell, Cynthia H; Bambery, Zoe; Roy, Kakoli; Meltzer, Martin I; Ahmed, Zara; Payne, Rebecca L; Bunnell, Rebecca E

    To reduce the health security risk and impact of outbreaks around the world, the US Centers for Disease Control and Prevention and its partners are building capabilities to prevent, detect, and contain outbreaks in 49 global health security priority countries. We examine the extent of economic vulnerability to the US export economy posed by trade disruptions in these 49 countries. Using 2015 US Department of Commerce data, we assessed the value of US exports and the number of US jobs supported by those exports. US exports to the 49 countries exceeded $308 billion and supported more than 1.6 million jobs across all US states in agriculture, manufacturing, mining, oil and gas, services, and other sectors. These exports represented 13.7% of all US export revenue worldwide and 14.3% of all US jobs supported by all US exports. The economic linkages between the United States and these global health security priority countries illustrate the importance of ensuring that countries have the public health capacities needed to control outbreaks at their source before they become pandemics.

  7. Relevance of Global Health Security to the US Export Economy

    PubMed Central

    Cassell, Cynthia H.; Bambery, Zoe; Roy, Kakoli; Meltzer, Martin I.; Ahmed, Zara; Payne, Rebecca L.

    2017-01-01

    To reduce the health security risk and impact of outbreaks around the world, the US Centers for Disease Control and Prevention and its partners are building capabilities to prevent, detect, and contain outbreaks in 49 global health security priority countries. We examine the extent of economic vulnerability to the US export economy posed by trade disruptions in these 49 countries. Using 2015 US Department of Commerce data, we assessed the value of US exports and the number of US jobs supported by those exports. US exports to the 49 countries exceeded $308 billion and supported more than 1.6 million jobs across all US states in agriculture, manufacturing, mining, oil and gas, services, and other sectors. These exports represented 13.7% of all US export revenue worldwide and 14.3% of all US jobs supported by all US exports. The economic linkages between the United States and these global health security priority countries illustrate the importance of ensuring that countries have the public health capacities needed to control outbreaks at their source before they become pandemics. PMID:29199867

  8. 75 FR 22758 - Intent To Prepare a Draft Environmental Impact Statement for Improvements to the U.S. 17 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... Environmental Impact Statement for Improvements to the U.S. 17 and Market Street (U.S. 17 Business) Corridor in... and Market Street (U.S. 17 Business) corridor in northern New Hanover and southern Pender Counties... are being evaluated as part of the U.S. 17 Corridor Study. The purpose of the U.S. 17 Corridor Study...

  9. 7 CFR 51.624 - U.S. Combination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Combination. 51.624 Section 51.624 Agriculture... § 51.624 U.S. Combination. “U.S. Combination” consists of a combination of U.S. No. 1 and U.S. No. 2 grapefruit: Provided, That the number of U.S. No. 2 fruits specified in § 51.628, Tables I and II, are not...

  10. Bottom-up or top-down: unit cost estimation of tuberculosis diagnostic tests in India.

    PubMed

    Rupert, S; Vassall, A; Raizada, N; Khaparde, S D; Boehme, C; Salhotra, V S; Sachdeva, K S; Nair, S A; Hoog, A H Van't

    2017-04-01

    Of 18 sites that participated in an implementation study of the Xpert® MTB/RIF assay in India, we selected five microscopy centres and two reference laboratories. To obtain unit costs of diagnostic tests for tuberculosis (TB) and drug-resistant TB. Laboratories were purposely selected to capture regional variations and different laboratory types. Both bottom-up and the top-down methods were used to estimate unit costs. At the microscopy centres, mean bottom-up unit costs were respectively US$0.83 (range US$0.60-US$1.10) and US$12.29 (US$11.61-US$12.89) for sputum smear microscopy and Xpert. At the reference laboratories, mean unit costs were US$1.69 for the decontamination procedure, US$9.83 for a solid culture, US$11.06 for a liquid culture, US$29.88 for a drug susceptibility test, and US$18.18 for a line-probe assay. Top-down mean unit cost estimates were higher for all tests, and for sputum smear microscopy and Xpert these increased to respectively US$1.51 and US$13.58. The difference between bottom-up and top-down estimates was greatest for tests performed at the reference laboratories. These unit costs for TB diagnostics can be used to estimate resource requirements and cost-effectiveness in India, taking into account geographical location, laboratory type and capacity utilisation.

  11. U.S. trade with Puerto Rico and U.S. possessions, 1996

    DOT National Transportation Integrated Search

    1997-03-01

    The official U.S. import and export statistics reflect both government and nongovernment shipments of merchandise between foreign countries and the U.S. Customs Territory (the 50 States, District of Columbia, and Puerto Rico), U.S. Foreign Trade Zone...

  12. 77 FR 73023 - U.S. Environmental Solutions Toolkit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... foreign end-users of environmental technologies that will outline U.S. approaches to a series of environmental problems and highlight participating U.S. vendors of relevant U.S. technologies. The Toolkit will... DEPARTMENT OF COMMERCE International Trade Administration U.S. Environmental Solutions Toolkit...

  13. Cost of treatment for multidrug-resistant tuberculosis in South Korea.

    PubMed

    Kang, Young Ae; Choi, Yong-Jun; Cho, Young-Jae; Lee, Sang Min; Yoo, Chul-Gyu; Kim, Young Whan; Han, Sung Koo; Shim, Young-Soo; Yim, Jae-Joon

    2006-11-01

    Costs associated with multidrug-resistant tuberculosis (MDR-TB) are higher than those associated with drug-susceptible TB because of the higher prices of second-line anti-TB drugs, the prolonged duration of treatment, greater productivity loss and higher mortality. The aim of this study was to estimate the cost of treatment for MDR-TB according to the treatment strategy and prognosis in South Korea. We estimated the direct (medical and non-medical) and indirect cost for the treatment of MDR-TB according to the treatment strategies and prognosis: in medically treated, surgically treated and deceased patients groups. The same analyses were undertaken for drug-susceptible TB for comparison. The patients with MDR-TB or drug-susceptible TB were randomly selected from the TB cohort of Seoul National University Hospital, Seoul, South Korea. Direct costs per person were US$4000 (US$2527-4841) in the medically treated group, US$17,457 (US$10,133-26,418) in the surgically treated group and US$33,362 (US$25 386-40 338) in the deceased group. Total costs per person were US$15,856 (US$10,752-38,421), US$47,159 (US$20,587-77,622) and US$478,357 (US$257,377-777,778), respectively. For the patients with drug-susceptible TB, the total cost ranged from US$1680 to US$7637 (median US$2166). The cost for the treatment of MDR-TB is seven to 22 times that of managing the drug-susceptible TB in South Korea. Considering the high cost, transmissibility and considerable fatality of MDR-TB, there is a need to provide specific separate funding for multidrug-resistant tuberculosis.

  14. Source apportionments of aerosols and their direct radiative forcing and long-term trends over continental United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Yang; Wang, Hailong; Smith, Steven J.

    Due to US air pollution regulations, aerosol and precursor emissions have decreased during recent decades, while changes in emissions in other regions of the world also influence US aerosol trends through long-range transport. We examine here the relative roles of these domestic and foreign emission changes on aerosol concentrations and direct radiative forcing (DRF) at the top of the atmosphere over the continental US. Long-term (1980-2014) trends and aerosol source apportionment are quantified in this study using a global aerosol-climate model equipped with an explicit aerosol source tagging technique. Due to US emission control policies, the annual mean near-surface concentrationmore » of particles, consisting of sulfate, black carbon, and primary organic aerosol, decreases by about –1.1 (±0.1) / –1.4 (±0.1) μg m -3 in western US and –3.3 (±0.2) / –2.9 (±0.2) μg m -3 in eastern US during 2010–2014, as compared to those in 1980–1984. Meanwhile, decreases in US emissions lead to a warming of +0.48 (±0.03) / –0.46 (±0.03) W m -2 in western US and +1.41 (±0.07) /+1.32 (±0.09) W m -2 in eastern US through changes in aerosol DRF. Increases in emissions from East Asia generally have a modest impact on US air quality, but mitigated the warming effect induced by reductions in US emissions by 25% in western US and 7% in eastern US. Thus, as US domestic aerosol and precursor emissions continue to decrease, foreign emissions may become increasingly important to radiative forcing over the US.« less

  15. Source apportionments of aerosols and their direct radiative forcing and long-term trends over continental United States

    DOE PAGES

    Yang, Yang; Wang, Hailong; Smith, Steven J.; ...

    2018-05-23

    Due to US air pollution regulations, aerosol and precursor emissions have decreased during recent decades, while changes in emissions in other regions of the world also influence US aerosol trends through long-range transport. We examine here the relative roles of these domestic and foreign emission changes on aerosol concentrations and direct radiative forcing (DRF) at the top of the atmosphere over the continental US. Long-term (1980-2014) trends and aerosol source apportionment are quantified in this study using a global aerosol-climate model equipped with an explicit aerosol source tagging technique. Due to US emission control policies, the annual mean near-surface concentrationmore » of particles, consisting of sulfate, black carbon, and primary organic aerosol, decreases by about –1.1 (±0.1) / –1.4 (±0.1) μg m -3 in western US and –3.3 (±0.2) / –2.9 (±0.2) μg m -3 in eastern US during 2010–2014, as compared to those in 1980–1984. Meanwhile, decreases in US emissions lead to a warming of +0.48 (±0.03) / –0.46 (±0.03) W m -2 in western US and +1.41 (±0.07) /+1.32 (±0.09) W m -2 in eastern US through changes in aerosol DRF. Increases in emissions from East Asia generally have a modest impact on US air quality, but mitigated the warming effect induced by reductions in US emissions by 25% in western US and 7% in eastern US. Thus, as US domestic aerosol and precursor emissions continue to decrease, foreign emissions may become increasingly important to radiative forcing over the US.« less

  16. Patients' with type 2 diabetes willingness to pay for insulin therapy and clinical outcomes

    PubMed Central

    Feher, Michael D; Brazier, John; Schaper, Nicolaas; Vega-Hernandez, Gabriela; Bøgelund, Mette

    2016-01-01

    Objectives This study assessed patient preferences, using willingness to pay as a method to measure different treatment characteristics or attributes associated with injectable insulin therapy in patients with type 2 diabetes. Research design and methods Adults with type 2 diabetes in 12 countries, diagnosed >6 months prior and receiving insulin for >3 months, were recruited through a representative online panel. Data were collected via online questionnaire and analyzed using a standard choice model for discrete choice experiment. Results A total of 3758 patients from North America (n=646), South America (n=1537), and Europe (n=1575) completed the study. Mean glycated hemoglobin (HbA1c) levels in North America, South America, and Europe were 63 mmol/mol (7.9%), 75 mmol/mol (9.0%), and 64 mmol/mol (8.0%), respectively. In the three regions, monthly willingness to pay was US$116, US$74, and US$92, respectively, for a 1%-point decrease in HbA1c; US$99, US$80, and US$104 for one less major hypoglycemic event per year; and US$64, US$37 and US$60 for a 3 kg weight decrease. To avoid preinjection preparation of insulin, the respective values were US$47, US$18, and US$37, and US$25, US$25, and US$24 for one less injection per day. Among respondents on basal-only insulin who had previously tried a more intensive regimen, reasons for switching back included difficulty in handling multiple injections and risk of hypoglycemic events. Conclusions Reducing HbA1c, frequency of major hypoglycemic events and weight decrease were the highest valued outcomes in each region. The administrative burden of injections was also considered important. PMID:27158518

  17. SYMPTOMS OF ANXIETY ON BOTH SIDES OF THE US-MEXICO BORDER: THE ROLE OF IMMIGRATION

    PubMed Central

    Borges, Guilherme; Zamora, Beatriz; García, José; Orozco, Ricardo; Cherpitel, Cheryl J.; Zemore, Sarah E.; Breslau, Joshua

    2014-01-01

    Home to about 15 million people, the US-Mexico border area has suffered stresses from increased border security efforts and a costly drug war in Mexico. Whether immigration patterns add to increasing levels of anxiety for the Mexican population and the Mexican-origin individuals living in the US-Mexico border and near the border is unknown. We used the US-Mexico Study on Alcohol and Related Conditions (UMSARC), a cross-sectional survey (2011–2013) of individuals living in border and non-border cities of the US (n=2,336) and Mexico (n=2,460). In Mexico respondents were asked if they ever migrated to the US or have a family member living in the US (328) or not (2,124), while in the US respondents were asked if they were born in Mexico (697), born in the US with no US-born parents (second generation, 702) or born in the US with at least one US-born parent (third generation, 932). The prevalence and risk factors for symptoms of anxiety using the Beck Anxiety Inventory (>=10) were obtained. Mexicans with no migrant experience had a prevalence of anxiety and adjusted prevalence ratio (PR) within the last month of 6.7% (PR=reference), followed by Mexicans with migration experience of 13.1% (PR=1.8), Mexican-born respondents living in the US of 17.3% (PR=2.6), US born Mexican-Americans of 2nd generation of 18.6% (PR=3.3) and finally US born 3rd+ generation of 25.9% (PR=3.8). Results help to identify regions and migration patterns at high risk for anxiety and may help to unravel causal mechanisms that underlie this risk. PMID:25543519

  18. Could US mayors achieve the entire US Paris climate target?

    NASA Astrophysics Data System (ADS)

    Gurney, K. R.; Huang, J.; Hutchins, M.; Liang, J.

    2017-12-01

    After the recent US Federal Administration announcement not to adhere to the Paris Accords, 359 mayors (and counting) in the US pledged to maintain their commitments, reducing emissions within their jurisdictions by 26-28% from their 2005 levels by the year 2025. While important, this leaves a large portion of the US landscape, and a large amount of US emissions, outside of the Paris commitment. With Federal US policy looking unlikely to change, could additional effort by US cities overcome the gap in national policy and achieve the equivalent US national Paris commitment? How many cities would be required and how deep would reductions need to be? Up until now, this question could not be reliably resolved due to lack of data at the urban scale. Here, we answer this question with new data - the Vulcan V3.0 FFCO2 emissions data product - through examination of the total US energy related CO2 emissions from cities. We find that the top 500 urban areas in the US could meet the national US commitment to the Paris Accords with a reduction of roughly 30% below their 2015 levels by the year 2025. This is driven by the share of US emissions emanating from cities, particularly the largest cohort. Indeed, as the number of urban areas taking on CO2 reduction targets grows, the less the reduction burden on any individual city. In this presentation, we provide an analysis of US urban CO2 emissions and US climate policy, accounting for varying definitions of urban areas, emitting sectors and the tradeoff between the number of policy-active cities and the CO2 reduction burden.

  19. Symptoms of anxiety on both sides of the US-Mexico border: the role of immigration.

    PubMed

    Borges, Guilherme; Zamora, Beatriz; García, José; Orozco, Ricardo; Cherpitel, Cheryl J; Zemore, Sarah E; Breslau, Joshua

    2015-02-01

    Home to about 15 million people, the US-Mexico border area has suffered stresses from increased border security efforts and a costly drug war in Mexico. Whether immigration patterns add to increasing levels of anxiety for the Mexican population and the Mexican-origin individuals living in the US-Mexico border and near the border is unknown. We used the US-Mexico Study on Alcohol and Related Conditions (UMSARC), a cross-sectional survey (2011-2013) of individuals living in border and non-border cities of the US (n = 2336) and Mexico (n = 2460). In Mexico respondents were asked if they ever migrated to the US or have a family member living in the US (328) or not (2124), while in the US respondents were asked if they were born in Mexico (697), born in the US with no US-born parents (second generation, 702) or born in the US with at least one US-born parent (third generation, 932). The prevalence and risk factors for symptoms of anxiety using the Beck Anxiety Inventory (>=10) were obtained. Mexicans with no migrant experience had a prevalence of anxiety and adjusted prevalence ratio (PR) within the last month of 6.7% (PR = reference), followed by Mexicans with migration experience of 13.1% (PR = 1.8), Mexican-born respondents living in the US of 17.3% (PR = 2.6), US born Mexican-Americans of 2nd generation of 18.6% (PR = 3.3) and finally US born 3rd + generation of 25.9% (PR = 3.8). Results help to identify regions and migration patterns at high risk for anxiety and may help to unravel causal mechanisms that underlie this risk. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. AmeriFlux US-SCs Southern California Climate Gradient - Coastal Sage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goulden, Mike

    This is the AmeriFlux version of the carbon flux data for the site US-SCs Southern California Climate Gradient - Coastal Sage. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a coastal sage shrubland. Coastal sage is a small stature, closed canopy vegetation dominated by drought deciduous shrubs. The site has historically burned every 10-20 years, with the wild fire in October 2007. The tower data sets includes this recovery process.

  1. What we need to know when performing and interpreting US elastography

    PubMed Central

    Park, So Hyun; Kim, So Yeon; Suh, Chong Hyun; Lee, Seung Soo; Kim, Kyoung Won; Lee, So Jung; Lee, Moon-Gyu

    2016-01-01

    According to the increasing need for accurate staging of hepatic fibrosis, the ultrasound (US) elastography techniques have evolved significantly over the past two decades. Currently, US elastography is increasingly used in clinical practice. Previously published studies have demonstrated the excellent diagnostic performance of US elastography for the detection and staging of liver fibrosis. Although US elastography may seem easy to perform and interpret, there are many technical and clinical factors which can affect the results of US elastography. Therefore, clinicians who are involved with US elastography should be aware of these factors. The purpose of this article is to present a brief overview of US techniques with the relevant technology, the clinical indications, diagnostic performance, and technical and biological factors which should be considered in order to avoid misinterpretation of US elastography results. PMID:27729637

  2. Active contour configuration model for estimating the posterior ablative margin in image fusion of real-time ultrasound and 3D ultrasound or magnetic resonance images for radiofrequency ablation: an experimental study.

    PubMed

    Lee, Junkyo; Lee, Min Woo; Choi, Dongil; Cha, Dong Ik; Lee, Sunyoung; Kang, Tae Wook; Yang, Jehoon; Jo, Jaemoon; Bang, Won-Chul; Kim, Jongsik; Shin, Dongkuk

    2017-12-21

    The purpose of this study was to evaluate the accuracy of an active contour model for estimating the posterior ablative margin in images obtained by the fusion of real-time ultrasonography (US) and 3-dimensional (3D) US or magnetic resonance (MR) images of an experimental tumor model for radiofrequency ablation. Chickpeas (n=12) and bovine rump meat (n=12) were used as an experimental tumor model. Grayscale 3D US and T1-weighted MR images were pre-acquired for use as reference datasets. US and MR/3D US fusion was performed for one group (n=4), and US and 3D US fusion only (n=8) was performed for the other group. Half of the models in each group were completely ablated, while the other half were incompletely ablated. Hyperechoic ablation areas were extracted using an active contour model from real-time US images, and the posterior margin of the ablation zone was estimated from the anterior margin. After the experiments, the ablated pieces of bovine rump meat were cut along the electrode path and the cut planes were photographed. The US images with the estimated posterior margin were compared with the photographs and post-ablation MR images. The extracted contours of the ablation zones from 12 US fusion videos and post-ablation MR images were also matched. In the four models fused under real-time US with MR/3D US, compression from the transducer and the insertion of an electrode resulted in misregistration between the real-time US and MR images, making the estimation of the ablation zones less accurate than was achieved through fusion between real-time US and 3D US. Eight of the 12 post-ablation 3D US images were graded as good when compared with the sectioned specimens, and 10 of the 12 were graded as good in a comparison with nicotinamide adenine dinucleotide staining and histopathologic results. Estimating the posterior ablative margin using an active contour model is a feasible way of predicting the ablation area, and US/3D US fusion was more accurate than US/MR fusion.

  3. New Cyber Chief: Cyberspace Must Become a National Security Priority

    Science.gov Websites

    of protection." Comments Closed Comments are closed. You will not be able to post a comment in this post. Follow Us! Follow Us on Facebook Follow Us on Twitter Follow Us on YouTube Follow Us on RSS

  4. 32 CFR 555.2 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

  5. 32 CFR 555.2 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

  6. 32 CFR 555.2 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

  7. 32 CFR 555.2 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...

  8. US SEEDLESS PINEAPPLE ORANGE

    USDA-ARS?s Scientific Manuscript database

    The Agricultural Research Service, U.S. Department of Agriculture, hereby releases for propagation the US SEEDLESS PINEAPPLE citrus scion selection, formerly tested as USDA 1-10-60. US SEEDLESS PINEAPPLE resulted from irradiation of Ridge Pineapple seeds by C.J. Hearn in 1970 at the U.S. Horticultu...

  9. Exploring the association of homicides in northern Mexico and healthcare access for US residents

    PubMed Central

    Geissler, Kimberley; Becker, Charles; Stearns, Sally; Thirumurthy, Harsha; Holmes, George M.

    2016-01-01

    Background Many legal residents in the United States (US)-Mexico border region cross from the US into Mexico for medical treatment and pharmaceuticals. We analyzed whether recent increases in homicides in Mexico are associated with reduced healthcare access for US border residents. Methods We used data on healthcare access, legal entries to the US from Mexico, and Mexican homicide rates (2002–2010). Poisson regression models estimated associations between homicide rates and total legal US entries. Multivariate difference-in-difference linear probability models evaluated associations between Mexican homicide rates and self-reported measures of healthcare access for US residents. Results Increased homicide rates were associated with decreased legal entries to the US from Mexico. Contrary to expectations, homicides did not have significant associations with healthcare access measures for legal residents in US border counties. Conclusions Despite a decrease in border crossings, increased violence in Mexico did not appear to negatively affect access for US border residents. PMID:24917240

  10. US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview

    DTIC Science & Technology

    2017-11-01

    ARL-TR-8199 ● NOV 2017 US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing...US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview by Roger P...TITLE AND SUBTITLE US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview 5a. CONTRACT NUMBER 5b. GRANT

  11. Health Issues for the Hmong Population in the U.S.: Implications for Health Educators

    ERIC Educational Resources Information Center

    Pinzon-Perez, Helda

    2006-01-01

    The Hmong population in the US has grown since 1975. According to the 2000 US census, there are more than 160,000 Hmong living in the US. New waves of Hmong immigrants are re-settling in the US. Over 15,000 Hmong have come to the US from Thailand as refugees since summer 2004. California, Minnesota, and Wisconsin are the States with the highest…

  12. Usher syndrome in the city of Birmingham—prevalence and clinical classification

    PubMed Central

    Hope, C; Bundey, S; Proops, D; Fielder, A

    1997-01-01

    AIMS—To estimate the prevalence of Usher syndrome in the city of Birmingham, and to establish a database of patients who have been classified into different clinical subtypes essential for future gene mutation analysis.
METHODS—Symptomatic cases of Usher syndrome (US) resident in the city of Birmingham in June 1994 were ascertained through multiple sources. Ophthalmic and audiological reassessment together with examination of medical records and patient questionnaires allowed classification of three subtypes, US 1, US 2, and US 3. In addition, family pedigrees were examined and blood was taken from index patients for DNA extraction.
RESULTS—In the population aged over 15 years the prevalence was 6.2 per 100 000 population for all US subtypes. The prevalence for US 1 and US 2 was 5.3 per 100 000 population. This is greater than previously reported. In the age group 30-49 years the prevalence approached 1 in 10 000. Clinical classification found 33% US 1, 47% US 2, and 20% US 3.
CONCLUSION—This higher prevalence rate and greater frequency of US 2 and US 3 may reflect a more complete ascertainment.

 PMID:9135408

  13. An Historical Examination of the Development of Emergency Medical Services Education in the US through Key Reports (1966-2014).

    PubMed

    Brooks, Ingrid A; Sayre, Michael R; Spencer, Caroline; Archer, Frank L

    2016-02-01

    The Emergency Medical Services (EMS) approach to emergency prehospital care in the United States (US) has global influence. As the 50-year anniversary of modern US EMS approaches, there is value in examining US EMS education development over this period. This report describes US EMS education milestones and identifies themes that provide context to readers outside the US. As US EMS education is described mainly in publications of federal US EMS agencies and associations, a Google search and hand searching of documents identified publications in the public domain. MEDLINE and CINAHL Plus were searched for peer reviewed publications. Documents were reviewed using both a chronological and thematic approach. Seventy-eight documents and 685 articles were screened, the full texts of 175 were reviewed, and 41 were selected for full review. Four historical periods in US EMS education became apparent: EMS education development (1966-1980); EMS education consolidation and review (1981-1989); EMS education reflection and change (1990-1999); and EMS education for the future (2000-2014). Four major themes emerged: legislative authority, physician direction, quality, and development of the profession. Documents produced through broad interprofessional consultations, with support from federal and US EMS authorities, reflect the catalysts for US EMS education development. The current model of US EMS education provides a structure to enhance educational quality into the future. Implementation evaluation of this model would be a valuable addition to the US EMS literature. The themes emerging from this review assist the understanding of the characteristics of US EMS education.

  14. Accuracy of volume measurement using 3D ultrasound and development of CT-3D US image fusion algorithm for prostate cancer radiotherapy.

    PubMed

    Baek, Jihye; Huh, Jangyoung; Kim, Myungsoo; Hyun An, So; Oh, Yoonjin; Kim, DongYoung; Chung, Kwangzoo; Cho, Sungho; Lee, Rena

    2013-02-01

    To evaluate the accuracy of measuring volumes using three-dimensional ultrasound (3D US), and to verify the feasibility of the replacement of CT-MR fusion images with CT-3D US in radiotherapy treatment planning. Phantoms, consisting of water, contrast agent, and agarose, were manufactured. The volume was measured using 3D US, CT, and MR devices. A CT-3D US and MR-3D US image fusion software was developed using the Insight Toolkit library in order to acquire three-dimensional fusion images. The quality of the image fusion was evaluated using metric value and fusion images. Volume measurement, using 3D US, shows a 2.8 ± 1.5% error, 4.4 ± 3.0% error for CT, and 3.1 ± 2.0% error for MR. The results imply that volume measurement using the 3D US devices has a similar accuracy level to that of CT and MR. Three-dimensional image fusion of CT-3D US and MR-3D US was successfully performed using phantom images. Moreover, MR-3D US image fusion was performed using human bladder images. 3D US could be used in the volume measurement of human bladders and prostates. CT-3D US image fusion could be used in monitoring the target position in each fraction of external beam radiation therapy. Moreover, the feasibility of replacing the CT-MR image fusion to the CT-3D US in radiotherapy treatment planning was verified.

  15. The role of ultrasound in graduate anatomy education: Current state of integration in the United States and faculty perceptions.

    PubMed

    Royer, Danielle F

    2016-10-01

    Ultrasound (US) is increasingly taught in medical schools, where it has been shown to be a valuable adjunct to anatomy training. To determine the extent of US training in nonmedical anatomy programs, and evaluate anatomists' perceptions on the role of US in anatomy education, an online survey was distributed to faculty in anatomy Master's and Doctoral programs. Survey results sampled 71% of anatomy graduate degree programs nationally. Of the faculty surveyed, 65% report little to no experience with US. Thirty-six percent of programs surveyed incorporate exposure to US, while only 15% provide hands-on US training. Opportunities for anatomy trainees to teach with US were found in 12% of programs. Likert responses indicated that anatomists hold overwhelmingly positive views on the contributions of US to anatomy education: 91% agreed US reinforces anatomical concepts (average 4.33 ± 0.68), 95% agreed it reinforces clinical correlates (average 4.43 ± 0.65). Anatomists hold moderately positive views on the value of US to the future careers of anatomy graduates: 69% agreed US increases competitiveness on the job market (average 3.91 ± 0.90), 85% agreed US is a useful skill for a medical school teaching career (average 4.24 ± 0.75), and 41% agreed that US should be required for a medical education career (average 3.34 ± 1.09). With continued improvements in technology and the widespread adoption of US into diverse areas of clinical practice, medical education is on the cusp of a paradigm shift with regards to US. Anatomists must decide whether US is an essential skills for the modern anatomist. Anat Sci Educ 9: 453-467. © 2016 American Association of Anatomists. © 2016 American Association of Anatomists.

  16. TOXICITY TESTING, RISK ASSESSMENT, AND OPTIONS FOR DREDGED MATRIAL MANAGEMENT

    EPA Science Inventory

    The U.S. Environmental Protection Agency (U.S. EPA), in conjunction with the U.S. Army Corps of Engineers (U.S. ACE), has lead responsibility for developing guidelines that provide environmental criteria for evaluating proposed discharges of dredged material into U.S. waters. To ...

  17. 78 FR 14773 - U.S. Environmental Solutions Toolkit-Landfill Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-07

    ... and foreign end-users of environmental technologies that will outline U.S. approaches to a series of environmental problems and highlight participating U.S. vendors of relevant U.S. technologies. The Toolkit will... DEPARTMENT OF COMMERCE International Trade Administration U.S. Environmental Solutions Toolkit...

  18. STEM Interns Get Real-World Experience in NHRC's Virtual Reality Lab

    Science.gov Websites

    stated purpose of this DoD website. Comments Closed Comments are closed. You will not be able to post a comment in this post. Follow Us! Follow Us on Facebook Follow Us on Twitter Follow Us on YouTube Follow Us

  19. 78 FR 58520 - U.S. Environmental Solutions Toolkit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-24

    ... notice sets forth a request for input from U.S. businesses capable of exporting their goods or services... and foreign end-users of environmental technologies The Toolkit outline U.S. approaches to a series of environmental problems and highlight participating U.S. vendors of relevant U.S. technologies. The Toolkit will...

  20. USPAS | U.S. Particle Accelerator School

    Science.gov Websites

    U.S. Particle Accelerator School U.S. Particle Accelerator School U.S. Particle Accelerator School U.S. Particle Accelerator School Education in Beam Physics and Accelerator Technology Home About About University Credits Joint International Accelerator School University-Style Programs Symposium-Style Programs

  1. 76 FR 65207 - U.S. Customs and Border Protection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Notice of Cancellation of Customs Broker Licenses AGENCY: U.S. Customs and Border Protection, U.S. Department of Homeland Security.... 1641) and the U.S. Customs and Border Protection regulations (19 CFR 111.51), the following Customs...

  2. 75 FR 70215 - Environmental Technologies Trade Advisory Committee (ETTAC), Request for Nominations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... relating to U.S. environmental technologies exports; U.S. Government policies and programs on the export of U.S. environmental products, technologies, and services; the effect of foreign governments' policies... and services companies, U.S. trade associations, and U.S. private sector organizations involved in the...

  3. Congressional Nominations to U.S. Service Academies: An Overview and Resources for Outreach and Management

    DTIC Science & Technology

    2016-04-21

    Congressional Nominations to U.S. Service Academies: An Overview and Resources for Outreach and Management R. Eric Petersen Specialist in...www.crs.gov RL33213 Congressional Nominations to U.S. Service Academies: An Overview Congressional Research Service Summary Members of Congress are...authorized by law to nominate candidates for appointment to four U.S. service academies. These schools are the U.S. Military Academy, the U.S. Naval

  4. 77 FR 31899 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... Trading of iShares Strategic Beta U.S. Large Cap Fund and iShares Strategic Beta U.S. Small Cap Fund Under... Fund Shares''): iShares Strategic Beta U.S. Large Cap Fund and iShares Strategic Beta U.S. Small Cap...: \\3\\ iShares Strategic Beta U.S. Large Cap Fund and iShares Strategic Beta U.S. Small Cap Fund (each...

  5. Projection of U.S. forest sector carbon sequestration under U.S. and global timber market and wood energy consumption scenarios, 2010-2060

    Treesearch

    Prakash Nepal; Peter J. Ince; Kenneth E. Skog; Sun J. Chang

    2012-01-01

    This study provides a modeling framework to examine change over time in U.S. forest sector carbon inventory (in U.S. timberland tree biomass and harvested wood products) for alternative projections of U.S. and global timber markets, including wood energy consumption, based on established IPCC/RPA scenarios. Results indicated that the U.S. forest sector’s projected...

  6. Tankering Fuel: A Cost Saving Initiative

    DTIC Science & Technology

    2011-05-01

    USAF AFIT/IMO/ENS/11-06 DEPARTMENT OF THE AIR FORCE AIR UNIVERSITY AIR FORCE INSTITUTE OF TECHNOLOGY Wright- Patterson Air Force Base, Ohio...NORTHCOM DFSP Verona DESC New York US NULL NORTHCOM DFSP Watson DESC California US NULL NORTHCOM DFSP WILLIAMS DESC FLOATING US NULL NORTHCOM DFSP...ANG KOKC AF Oklahoma US ANG NORTHCOM Willow Grove ANG KNXX AF Pennsylvania US ANG NORTHCOM Wright Patterson KFFO AF Ohio US AFMC NORTHCOM WV ARNG

  7. 76 FR 46889 - U.S. Advisory Panel to the U.S. Section of the North Pacific Anadromous Fish Commission; Notice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... DEPARTMENT OF STATE [Public Notice 7476] U.S. Advisory Panel to the U.S. Section of the North Pacific Anadromous Fish Commission; Notice of Renewal The Department of State has renewed the Charter of the U.S. Advisory Panel to the U.S. Section of the North Pacific Anadromous Fish Commission (NPAFC) for another two years. The NPAFC was established...

  8. U.S. Crude Oil and Natural Gas Proved Reserves

    EIA Publications

    2016-01-01

    U.S. oil and natural gas proved reserves declined in 2015 due to lower prices. U.S. crude oil and lease condensate proved reserves declined 4.7 billion barrels (11.8%) from their year-end 2014 level to 35.2 billion barrels at year-end 2015, according to U.S. Crude Oil and Natural Gas Proved Reserves, Year-end 2015, released today by the U.S. Energy Information Administration. U.S natural gas proved reserves decreased 64.5 trillion cubic feet, a 16.6% decline, reducing the U.S. total to 324.3 Tcf at year-end 2015.

  9. [Unit cost variation in a social security company in Querétaro, México].

    PubMed

    Villarreal-Ríos, Enrique; Campos-Esparza, Maribel; Garza-Elizondo, María E; Martínez-González, Lidia; Núñez-Rocha, Georgina M; Romero-Islas, Nestor R

    2006-01-01

    Comparing unit cost variation between departments and reasons for consultation in outpatient health services provided by a social security company from Querétaro, Mexico. A study of costs (in US dollars) was carried out in outpatient health service units during 2004. Fixed unit costs were estimated per department and adjusted for one year's productivity. Material, physical and consumer resources were included. Weighting was assigned to resources invested in each department. Unit cost was estimated by using the micro cost technique; medicaments, materials used during treatment and reagents were considered to be consumer items. Unit cost resulted from adding fixed unit cost to the variable unit cost corresponding to the reason for consulting. Units costs were then compared between the medical units. Unit cost per month for diabetic treatment varied from 34.8 US dollars, 32,2 US dollars to US 34 US dollars, pap smear screening test costs were 7,2 US dollars, 8,7 US dollars and 7,3 US dollars and dental treatment 27 US dollars, 33 US dollars, 6 and 28,7 US dollars. Unit cost variation was more important in the emergency room and the dental service.

  10. The Us2 gene product of herpes simplex virus 2 is a membrane-associated ubiquitin-interacting protein.

    PubMed

    Kang, Ming-Hsi; Roy, Bibhuti B; Finnen, Renée L; Le Sage, Valerie; Johnston, Susan M; Zhang, Hui; Banfield, Bruce W

    2013-09-01

    The Us2 gene encodes a tegument protein that is conserved in most members of the Alphaherpesvirinae. Previous studies on the pseudorabies virus (PRV) Us2 ortholog indicated that it is prenylated, associates with membranes, and spatially regulates the enzymatic activity of the MAP (mitogen-activated protein) kinase ERK (extracellular signal-related kinase) through direct binding and sequestration of ERK at the cytoplasmic face of the plasma membrane. Here we present an analysis of the herpes simplex virus 2 (HSV-2) Us2 ortholog and demonstrate that, like PRV Us2, HSV-2 Us2 is a virion component and that, unlike PRV Us2, it does not interact with ERK in yeast two-hybrid assays. HSV-2 Us2 lacks prenylation signals and other canonical membrane-targeting motifs yet is tightly associated with detergent-insoluble membranes and localizes predominantly to recycling endosomes. Experiments to identify cellular proteins that facilitate HSV-2 Us2 membrane association were inconclusive; however, these studies led to the identification of HSV-2 Us2 as a ubiquitin-interacting protein, providing new insight into the functions of HSV-2 Us2.

  11. A COMPARATIVE STUDY OF REAL-TIME AND STATIC ULTRASONOGRAPHY DIAGNOSES FOR THE INCIDENTAL DETECTION OF DIFFUSE THYROID DISEASE.

    PubMed

    Kim, Dong Wook

    2015-08-01

    The aim of this study was to compare the diagnostic accuracy of real-time and static ultrasonography (US) for the incidental detection of diffuse thyroid disease (DTD). In 118 consecutive patients, a single radiologist performed real-time US before thyroidectomy. For static US, the same radiologist retrospectively investigated the sonographic findings on a picture-archiving and communication system after 3 months. The diagnostic categories of both real-time and static US diagnoses were determined based on the number of abnormal findings, and the diagnostic indices were calculated by a receiver operating characteristic (ROC) curve analysis using the histopathologic results as the reference standard. Histopathologic results included normal thyroid (n = 77), Hashimoto thyroiditis (n = 11), non-Hashimoto lymphocytic thyroiditis (n = 29), and diffuse hyperplasia (n = 1). Normal thyroid and DTD showed significant differences in echogenicity, echotexture, glandular margin, and vascularity on both real-time and static US. There was a positive correlation between US categories and histopathologic results in both real-time and static US. The highest diagnostic indices were obtained when the cutoff criteria of real-time and static US diagnoses were chosen as indeterminate and suspicious for DTD, respectively. The ROC curve analysis showed that real-time US was superior to static US in diagnostic accuracy. Both real-time and static US may be helpful for the detection of incidental DTD, but real-time US is superior to static US for detecting incidental DTD.

  12. Robotic intrafractional US guidance for liver SABR: System design, beam avoidance, and clinical imaging.

    PubMed

    Schlosser, Jeffrey; Gong, Ren Hui; Bruder, Ralf; Schweikard, Achim; Jang, Sungjune; Henrie, John; Kamaya, Aya; Koong, Albert; Chang, Daniel T; Hristov, Dimitre

    2016-11-01

    To present a system for robotic 4D ultrasound (US) imaging concurrent with radiotherapy beam delivery and estimate the proportion of liver stereotactic ablative body radiotherapy (SABR) cases in which robotic US image guidance can be deployed without interfering with clinically used VMAT beam configurations. The image guidance hardware comprises a 4D US machine, an optical tracking system for measuring US probe pose, and a custom-designed robot for acquiring hands-free US volumes. In software, a simulation environment incorporating the LINAC, couch, planning CT, and robotic US guidance hardware was developed. Placement of the robotic US hardware was guided by a target visibility map rendered on the CT surface by using the planning CT to simulate US propagation. The visibility map was validated in a prostate phantom and evaluated in patients by capturing live US from imaging positions suggested by the visibility map. In 20 liver SABR patients treated with VMAT, the simulation environment was used to virtually place the robotic hardware and US probe. Imaging targets were either planning target volumes (PTVs, range 5.9-679.5 ml) or gross tumor volumes (GTVs, range 0.9-343.4 ml). Presence or absence of mechanical interference with LINAC, couch, and patient body as well as interferences with treated beams was recorded. For PTV targets, robotic US guidance without mechanical interference was possible in 80% of the cases and guidance without beam interference was possible in 60% of the cases. For the smaller GTV targets, these proportions were 95% and 85%, respectively. GTV size (1/20), elongated shape (1/20), and depth (1/20) were the main factors limiting the availability of noninterfering imaging positions. The robotic US imaging system was deployed in two liver SABR patients during CT simulation with successful acquisition of 4D US sequences in different imaging positions. This study indicates that for VMAT liver SABR, robotic US imaging of a relevant internal target may be possible in 85% of the cases while using treatment plans currently deployed in the clinic. With beam replanning to account for the presence of robotic US guidance, intrafractional US may be an option for 95% of the liver SABR cases.

  13. Evaluation of uterine ultrasound imaging in cervical radiotherapy; a comparison of autoscan and conventional probe

    PubMed Central

    Cooper, David T; Behrens, Claus F

    2016-01-01

    Objective: In cervical radiotherapy, it is essential that the uterine position is correctly determined prior to treatment delivery. The aim of this study was to evaluate an autoscan ultrasound (A-US) probe, a motorized transducer creating three-dimensional (3D) images by sweeping, by comparing it with a conventional ultrasound (C-US) probe, where manual scanning is required to acquire 3D images. Methods: Nine healthy volunteers were scanned by seven operators, using the Clarity® system (Elekta, Stockholm, Sweden). In total, 72 scans, 36 scans from the C-US and 36 scans from the A-US probes, were acquired. Two observers delineated the uterine structure, using the software-assisted segmentation in the Clarity workstation. The data of uterine volume, uterine centre of mass (COM) and maximum uterine lengths, in three orthogonal directions, were analyzed. Results: In 53% of the C-US scans, the whole uterus was captured, compared with 89% using the A-US. F-test on 36 scans demonstrated statistically significant differences in interobserver COM standard deviation (SD) when comparing the C-US with the A-US probe for the inferior–superior (p < 0.006), left–right (p < 0.012) and anteroposterior directions (p < 0.001). The median of the interobserver COM distance (Euclidean distance for 36 scans) was reduced from 8.5 (C-US) to 6.0 mm (A-US). An F-test on the 36 scans showed strong significant differences (p < 0.001) in the SD of the Euclidean interobserver distance when comparing the C-US with the A-US scans. The average Dice coefficient when comparing the two observers was 0.67 (C-US) and 0.75 (A-US). The predictive interval demonstrated better interobserver delineation concordance using the A-US probe. Conclusion: The A-US probe imaging might be a better choice of image-guided radiotherapy system for correcting for daily uterine positional changes in cervical radiotherapy. Advances in knowledge: Using a novel A-US probe might reduce the uncertainty in interoperator variability during ultrasound scanning. PMID:27452268

  14. Evaluation of uterine ultrasound imaging in cervical radiotherapy; a comparison of autoscan and conventional probe.

    PubMed

    Baker, Mariwan; Cooper, David T; Behrens, Claus F

    2016-10-01

    In cervical radiotherapy, it is essential that the uterine position is correctly determined prior to treatment delivery. The aim of this study was to evaluate an autoscan ultrasound (A-US) probe, a motorized transducer creating three-dimensional (3D) images by sweeping, by comparing it with a conventional ultrasound (C-US) probe, where manual scanning is required to acquire 3D images. Nine healthy volunteers were scanned by seven operators, using the Clarity(®) system (Elekta, Stockholm, Sweden). In total, 72 scans, 36 scans from the C-US and 36 scans from the A-US probes, were acquired. Two observers delineated the uterine structure, using the software-assisted segmentation in the Clarity workstation. The data of uterine volume, uterine centre of mass (COM) and maximum uterine lengths, in three orthogonal directions, were analyzed. In 53% of the C-US scans, the whole uterus was captured, compared with 89% using the A-US. F-test on 36 scans demonstrated statistically significant differences in interobserver COM standard deviation (SD) when comparing the C-US with the A-US probe for the inferior-superior (p < 0.006), left-right (p < 0.012) and anteroposterior directions (p < 0.001). The median of the interobserver COM distance (Euclidean distance for 36 scans) was reduced from 8.5 (C-US) to 6.0 mm (A-US). An F-test on the 36 scans showed strong significant differences (p < 0.001) in the SD of the Euclidean interobserver distance when comparing the C-US with the A-US scans. The average Dice coefficient when comparing the two observers was 0.67 (C-US) and 0.75 (A-US). The predictive interval demonstrated better interobserver delineation concordance using the A-US probe. The A-US probe imaging might be a better choice of image-guided radiotherapy system for correcting for daily uterine positional changes in cervical radiotherapy. Using a novel A-US probe might reduce the uncertainty in interoperator variability during ultrasound scanning.

  15. U.S. healthcare fix: leveraging the lessons from the food supply chain.

    PubMed

    Kumar, Sameer; Blair, John T

    2013-01-01

    U.S. healthcare costs consistently outpace inflation, causing growing problems of affordability. This trend cannot be sustained indefinitely. The purpose of this study is to use supply-chain tools for macro-level examination of the U.S. healthcare as a business system and identify options and best use practices. We compare the important and successful U.S. food industry to the essential but problematic U.S. healthcare industry. Supply chain strategies leading to food business operations success are examined and healthcare applications suggested. We emphasize "total cost of ownership" which includes all costs incurred by all stakeholders of U.S. healthcare, including maintenance and cleanup, not just the initial purchase price. U.S. hospitals and clinics can use supply chain strategies in a total cost of ownership framework to reduce healthcare costs while maintaining patient care quality. Supply chain strategies of resource pooling, mass customization, centralized logistics, specialization, postponement and continuous improvement that have been successfully used in the U.S. food industry should be more widely applied to the U.S. healthcare industry. New and growing areas of telemedicine and medical tourism should be included in the supply chain analysis of U.S. healthcare. Valid statistical analysis of results in all areas of U.S. healthcare is an important part of the process. U.S. healthcare industry problems are systematic operational and supply chain problems rather than problems with workforce or technology. Examination of the U.S. healthcare industry through a supply chain framework should lead to significant operational improvement in both prevention and treatment of acute and chronic ailments. A rational and unemotional reorganization of the U.S. healthcare system operations, using supply chain strategies, should help reduce healthcare costs while maintaining quality and increasing accessibility.

  16. [Value of combined conventional and contrast enhanced sonography in the evaluation of hepatic disorders].

    PubMed

    Tranquart, F; Bleuzen, A; Kissel, A

    2004-06-01

    To assess the value of combined conventional and contrast-material enhanced sonography for the characterization of focal liver lesions. Simultaneous imaging with grey scale and contrast enhanced US was performed in 90 patients following Levovist injection (Schering, Berlin, Germany) using the "Agent Detection Imaging" method (ADI, Siemens-Acuson, Mountain View, USA). US scanning was performed at least 4 minutes after contrast injection with review of both grayscale and contrast enhanced modes. Results for detection and characterization of lesions were compared to the selected gold standard imaging modality (CT or MRI). Final diagnoses included: 20 normal examinations, 41 patients with metastases, 6 patients with hepatocellular carcinoma, 13 patients with hemangioma, 6 patients with other benign lesions, 4 patients with cysts and 6 patients with two types of lesions. Delayed phase contrast enhanced US allowed diagnosis of all lesions except for one metastasis and all hepatocellular carcinomas. While the diagnosis of hepatoma could not be confirmed, the features suggested a malignant etiology. For 7 patients with metastases, more lesions were detected at ADI (4.9 lesions) than at conventional US (1.1 lesion). For 3 patients, CT showed more lesions than ADI US (3.3 versus 1.6 lesions). The accuracy of ADI US for differentiating between benign and malignant lesions was 98.7% compared to 49.6% for conventional US (p<0.001). The total number of lesions detected at ADI US was higher (p<0.01) than at conventional US and not significantly different from that obtained by the gold standard reference methods. Complete characterization was achieved in 92.2% of cases with ADI US compared to 59.2% with conventional US (p<0.001). Contrast-material enhanced US combined with conventional US markedly improves the diagnostic accuracy of US in terms of lesion detection and characterization.

  17. The cost of antiretroviral therapy in Haiti

    PubMed Central

    Koenig, Serena P; Riviere, Cynthia; Leger, Paul; Severe, Patrice; Atwood, Sidney; Fitzgerald, Daniel W; Pape, Jean W; Schackman, Bruce R

    2008-01-01

    Background We determined direct medical costs, overhead costs, societal costs, and personnel requirements for the provision of antiretroviral therapy (ART) to patients with AIDS in Haiti. Methods We examined data from 218 treatment-naïve adults who were consecutively initiated on ART at the GHESKIO Center in Port-au-Prince, Haiti between December 23, 2003 and May 20, 2004 and calculated costs and personnel requirements for the first year of ART. Results The mean total cost of treatment per patient was $US 982 including $US 846 in direct costs, $US 114 for overhead, and $US 22 for societal costs. The direct cost per patient included generic ART medications $US 355, lab tests $US 130, nutrition $US 117, hospitalizations $US 62, pre-ART evaluation $US 58, labor $US 51, non-ART medications $US 39, outside referrals $US 31, and telephone cards for patient retention $US 3. Higher treatment costs were associated with hospitalization, change in ART regimen, TB treatment, and survival for one year. We estimate that 1.5 doctors and 2.5 nurses are required to treat 1000 patients in the first year after initiating ART. Conclusion Initial ART treatment in Haiti costs approximately $US 1,000 per patient per year. With generic first-line antiretroviral drugs, only 36% of the cost is for medications. Patients who change regimens are significantly more expensive to treat, highlighting the need for less-expensive second-line drugs. There may be sufficient health care personnel to treat all HIV-infected patients in urban areas of Haiti, but not in rural areas. New models of HIV care are needed for rural areas using assistant medical officers and community health workers. PMID:18275615

  18. Post-acquisition repetitive thought in fear conditioning: an experimental investigation of the effect of CS-US-rehearsal.

    PubMed

    Joos, Els; Vansteenwegen, Debora; Hermans, Dirk

    2012-06-01

    Although repetitive thought (e.g., worry) is generally assumed to be a risk factor for psychopathological disorders such as anxiety disorders, the repetitive thought processes occurring after a conditioning event have not yet received much theoretical attention. However, as repetitive thought can be mimicked by (mental) rehearsal, which is well-known to enhance memory performance, it seems worthwhile to explore the role of rehearsal in conditioning. Therefore, the current study investigates the impact of rehearsing an acquired CS-US-contingency on subsequent conditioned fear responding. After acquiring two CS-US-contingencies with either a human scream or a white noise as US, participants were instructed to rehearse one of these CS-US-pairings during an experimental session as well as during the following week. Fear responding to the CS which was previously paired with the scream persisted in the participants who rehearsed the CS-US(scream)-contingency, but decreased in those participants who rehearsed the CS-US(noise)-contingency. The same pattern emerged in the US-expectancy ratings, but the effect failed to reach significance. For the CS which was paired with the noise-US, no rehearsal effect emerged. As acquisition to the noise-US was less pronounced and less robust as compared to the scream-US, claims regarding the rehearsal effect might be hampered for the CS-US(noise)-contingency. Repetitive post-acquisition activation of a CS-US-contingency impacts CR retention. As the USs were not rated as more intense, aversive or startling after rehearsal compared to post-acquisition, US-inflation is discarded as a possible explanation of this effect. Copyright © 2011 Elsevier Ltd. All rights reserved.

  19. Simple X-ray versus ultrasonography examination in blunt chest trauma: effective tools of accurate diagnosis and considerations for rib fractures.

    PubMed

    Hwang, Eun Gu; Lee, Yunjung

    2016-12-01

    Simple radiography is the best diagnostic tool for rib fractures caused by chest trauma, but it has some limitations. Thus, other tools are also being used. The aims of this study were to investigate the effectiveness of ultrasonography (US) for identifying rib fractures and to identify influencing factors of its effectiveness. Between October 2003 and August 2007, 201 patients with blunt chest trauma were available to undergo chest radiographic and US examinations for diagnosis of rib fractures. The two modalities were compared in terms of effectiveness based on simple radiographic readings and US examination results. We also investigated the factors that influenced the effectiveness of US examination. Rib fractures were detected on radiography in 69 patients (34.3%) but not in 132 patients. Rib fractures were diagnosed by using US examination in 160 patients (84.6%). Of the 132 patients who showed no rib fractures on radiography, 92 showed rib fractures on US. Among the 69 patients of rib fracture detected on radiography, 33 had additional rib fractures detected on US. Of the patients, 76 (37.8%) had identical radiographic and US results, and 125 (62.2%) had fractures detected on US that were previously undetected on radiography or additional fractures detected on US. Age, duration until US examination, and fracture location were not significant influencing factors. However, in the group without detected fractures on radiography, US showed a more significant effectiveness than in the group with detected fractures on radiography ( P =0.003). US examination could detect unnoticed rib fractures on simple radiography. US examination is especially more effective in the group without detected fractures on radiography. More attention should be paid to patients with chest trauma who have no detected fractures on radiography.

  20. M1A2 Adjunct Analysis (POSNOV Volume)

    DTIC Science & Technology

    1989-12-01

    MD 20814-2797 Director 2 U.S. Army Materiel Systems Analysis Activity ATTN: AMXSY-CS, AMXSY-GA Aberden Proving Grounds , MD 21005-5071 U.S. Army...Leonard Wood, MO Commander U.S. Army Ordnance Center & School ATTN: ATSL-CD-CS Aberdeen Proving Ground , MD 21005 Commander 2 U.S. Army Soldier Support...NJ Commander U.S. Army Test and Evaluation Command ATrN: AMSTE-CM-R Aberdeen Proving Ground , MD 21005 Commander U.S. Army Tank Automotive Command

  1. Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section

    DTIC Science & Technology

    2016-10-01

    ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop ...ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory...Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section 5a. CONTRACT NUMBER

  2. The Zwicky Transient Facility (ZTF) begins

    NASA Astrophysics Data System (ADS)

    Kulkarni, S. R.

    2018-02-01

    S. R. Kulkarni on behalf of the Zwicky Transient Facility (ZTF) announces the first confirmed results from the project. ZTF is led by the California Institute of Technology, US and includes IPAC, US; Los Alamos National Laboratory, US; University of Maryland, US; University of Wisconsin at Milwaukee, US; University of Washington, US; Oskar-Klein Center of the University of Stockholm, Sweden; DESY and Humboldt University of Berlin, Germany; Weizmann Institute of Science, Israel; and the University System of Taiwan, Taiwan.

  3. Engagement, Satisfaction, and Belonging of International Undergraduates at U.S. Research Universities

    ERIC Educational Resources Information Center

    Van Horne, Sam; Lin, Shuhui; Anson, Matthew; Jacobson, Wayne

    2018-01-01

    International students face challenges that their U.S. classmates rarely encounter, but few studies examine specific ways in which undergraduate experiences of international students compare to those of their U.S. classmates. This study examines U.S. and international student responses to an undergraduate survey administered at nine U.S. research…

  4. 78 FR 36520 - U.S. Department of Agriculture Multi-Family Housing Section 515-Underserved Counties and Colonias...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... DEPARTMENT OF AGRICULTURE Rural Housing Service U.S. Department of Agriculture Multi-Family...-Discrimination Statement The U.S. Department of Agriculture (USDA) prohibits discrimination against its customers... letter to us by mail at U.S. Department of Agriculture, Director, Office of Adjudication, 1400...

  5. Defense.gov Special Report: Unified Combatant Commands

    Science.gov Websites

    in support of U.S. strategic objectives. Their mission is to maintain command and control of U.S coverage and more information. Unified Combatant Command strategic map U.S. Northern Command NORTHCOM U.S U.S. Strategic Command STRATCOM . Main Menu Home Today in DOD About DOD Leaders Biographies

  6. Natural Hazards Observer. Volume XXV, Number 3

    DTIC Science & Technology

    2001-01-01

    National Science Foundation , Federal Emergency Management Agency, National Oceanic and Atmospheric Administration, U.S. (Geological Survey, U.S. Army Corps of Engineers, U.S. Environmental Protection Agency, U.S. Department of Transportation, U.S. Bureau of Reclamation, National Aeronautics and Space Administration, the Institute for Business and Home Safety, and the Public Entity Risk

  7. Natural Hazards Observer, Volume XXV No. 2, November 2000

    DTIC Science & Technology

    2000-11-01

    National Science Foundation , Federal Emergency Management Agency, National Oceanic and Atmospheric Administration, U.S. Geological Survey, U.S. Army Corps of Engineers, U.S. Environmental Protection Agency, U.S. Department of Transportation, U.S. Bureau of Reclamation, National Aeronautics and Space Administration, the Institute for Business and Home Safety, and the Public Entity Risk

  8. 32 CFR 761.10 - Persons: Group authorizations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Airspace Reservation. (b) Military members of the U.S. Armed Forces or U.S. civil service employees of the... military members of the U.S. Armed Forces and U.S. citizen dependents of U.S. civil service employees... 32 National Defense 5 2011-07-01 2011-07-01 false Persons: Group authorizations. 761.10 Section...

  9. 32 CFR 761.10 - Persons: Group authorizations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Airspace Reservation. (b) Military members of the U.S. Armed Forces or U.S. civil service employees of the... military members of the U.S. Armed Forces and U.S. citizen dependents of U.S. civil service employees... 32 National Defense 5 2010-07-01 2010-07-01 false Persons: Group authorizations. 761.10 Section...

  10. Navy.mil - Photo Galleries

    Science.gov Websites

    Status of the Navy Strategic Documents Command Directory Our Ships Fact Files Today in Naval History Defense.gov U.S. Army U.S. Air Force U.S. Marine Corps U.S. Coast Guard Naval History & Heritage Command Ships Fact Files Today in Naval History Contact Us Command Addresses (SNDL) FAQ Leadership Secretary of

  11. 31 CFR 510.310 - U.S. financial institution.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false U.S. financial institution. 510.310 Section 510.310 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... Definitions § 510.310 U.S. financial institution. The term U.S. financial institution means any U.S. entity...

  12. 31 CFR 510.310 - U.S. financial institution.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false U.S. financial institution. 510.310 Section 510.310 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... Definitions § 510.310 U.S. financial institution. The term U.S. financial institution means any U.S. entity...

  13. Joint Chiefs of Staff > Media > Photos

    Science.gov Websites

    U.S. Army Gen. Curtis M. Scaparrotti, left, Commander of U.S. European Command and Supreme Allied , Commander of U.S. European Command and Supreme Allied Commander, Europe; speaks after receiving the . U.S. Army Gen. Curtis M. Scaparrotti, Commander of U.S. European Command and Supreme Allied Commander

  14. 31 CFR 510.310 - U.S. financial institution.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false U.S. financial institution. 510.310 Section 510.310 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... Definitions § 510.310 U.S. financial institution. The term U.S. financial institution means any U.S. entity...

  15. THE BENEFITS OF WETLANDS: THE UPPER HALFWAY CREEK PROJECT

    EPA Science Inventory

    Researchers from the U.S. EPA are working in collaboration with U.S. Geological Survey and the U.S. Fish and Wildlife Services on this project. Upper Halfway Creek marsh is a constructed wetland managed by the U.S. Fish and Wildlife Service. This project will assist the U.S. EP...

  16. 78 FR 68888 - Self-Regulatory Organizations; The Options Clearing Corporation; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-15

    ... Options Clearing Corporation and NYSE Liffe US LLC in Connection With NYSE Liffe US LLC's Transition to... Services Agreement (``Clearing Agreement'') between OCC and NYSE Liffe US LLC (``NYSE Liffe US'') to make changes to the Clearing Agreement in connection with NYSE Liffe US' transition to electronic vault...

  17. Neo-Conned University

    ERIC Educational Resources Information Center

    Jones, Andee

    2014-01-01

    Censorship, says Australian political theorist John Keane (1991), can "echo within us, take up residence within ourselves, spying on us, a private amanuensis who reminds us never to go too far... It makes us zip our lips, tremble and think twice" (p. 39). It can also make us sick. The author states that this is her argument here: that,…

  18. Educational inequalities in self-rated health across US states and European countries.

    PubMed

    Präg, Patrick; Subramanian, S V

    2017-07-01

    The US shows a distinct health disadvantage when compared to other high-income nations. A potential lever to reduce this disadvantage is to improve the health situation of lower socioeconomic groups. Our objective is to explore how the considerable within-US variation in health inequalities compares to the health inequalities across other Western countries. Representative survey data from 44 European countries and the US federal states were obtained from the fourth wave of the European Values Study (EVS) and the 2008 wave of the Behavioral Risk Factor Surveillance System. Using binary logistic regression, we analyze different forms of educational inequalities in self-rated health (SRH), adjusted for age and sex. The extent of educational inequalities in SRH varies considerably over European countries and US states; with US states in general showing greater inequality, however, differences between US states and European countries are less clear than commonly assumed. The US has considerable differences in educational inequalities in SRH across geographic locations. To understand the reasons for the US health disadvantage, comparative research has to take into account the vast variation in health inequalities within the US.

  19. [Clinical application and optimization of HEAD-US quantitative ultrasound assessment scale for hemophilic arthropathy].

    PubMed

    Li, J; Guo, X J; Ding, X L; Lyu, B M; Xiao, J; Sun, Q L; Li, D S; Zhang, W F; Zhou, J C; Li, C P; Yang, R C

    2018-02-14

    Objective: To assess the feasibility of HEAD-US scale in the clinical application of hemophilic arthropathy (HA) and propose an optimized ultrasound scoring system. Methods: From July 2015 to August 2017, 1 035 joints ultrasonographic examinations were performed in 91 patients. Melchiorre, HEAD-US (Hemophilic Early Arthropathy Detection with UltraSound) and HEAD-US-C (HEAD-US in China) scale scores were used respectively to analyze the results. The correlations between three ultrasound scales and Hemophilia Joint Health Scores (HJHS) were evaluated. The sensitivity differences of the above Ultrasonic scoring systems in evaluation of HA were compared. Results: All the 91 patients were male, with median age of 16 (4-55) years old, including 86 cases of hemophilia A and 5 cases hemophilia B. The median ( P 25 , P 75 ) of Melchiorre, HEAD-US and HEAD-US-C scores of 1 035 joints were 2(0,6), 1(0,5) and 2(0,6), respectively, and the correlation coefficients compared with HJHS was 0.747, 0.762 and 0.765 respectively, with statistical significance ( P <0.001). The positive rates of Melchiorre, HEAD-US-C and HEAD-US scale score were 63.0% (95% CI 59.7%-65.9%), 59.5% (95% CI 56.5%-62.4%) and 56.6% (95% CI 53.6%-59.6%) respectively, and the difference was statistically significant ( P <0.001). Even for 336 cases of asymptomatic joints, the positive rates of Melchiorre, HEAD-US-C and HEAD-US scale score were 25.0% (95% CI 20.6%-29.6%), 17.0% (95% CI 12.6%-21.1%) and 11.9% (95% CI 8.4%-15.7%) respectively, and the difference was statistically significant ( P <0.001). There were significant changes ( P <0.05) in the ultrasonographic score of HA before and after onset of hemorrhage in 107 joints of 40 patients. The difference in variation amplitude of HEAD-US-C scores and HEAD-US scores before and after joint bleeding was statistically significant ( P <0.001). Conclusion: Compared with Melchiorre, there were similar good correlations between HEAD-US, HEAD-US-C and HJHS. HEAD-US ultrasound scoring system is quick, convenient and simple to use. The optimized HEAD-US-C scale score is more sensitive than HEAD-US, especially for patients with HA who have subclinical state, which make up for insufficiency of sensitivity in HEAD-US scoring system.

  20. Morning Sickness

    MedlinePlus

    ... Join us on Facebook Follow us on Twitter Instagram: behind the scenes Research & Professionals Our research Research ... Join us on Facebook Follow us on Twitter Instagram: behind the scenes Our research Research grants Prematurity ...

  1. Congressional Black Caucus meets with NASA

    NASA Image and Video Library

    2010-01-13

    NASA Administrator Charles Bolden, space shuttle crew STS-129 and members of the Congressional Black Caucus pose for a group photo at the Capitol Building, Wednesday, Jan. 13, 2010, in Washington. Back row from left to right: U.S. Rep Donna Edwards (D-MD), U.S. Rep Diane Watson (D-CA), NASA Administrator Charles Bolden, astronauts Leland Melvin, Mike Foreman, Robert Satcher, Barry Wilmore, Randy Breznik, and U.S. Rep Mel Watt (D-NC). Front row from left to right: U.S. Rep Robert Scott (D-VA), U.S. Rep. Corrine Brown (D-Fla), U.S. Rep. Barbara Lee (D-CA), U.S. Rep. Donna Christensen (D-VI) and U.S. Rep. Donald Payne (D-NJ). The crew of STS-129 presented the CBC with a montage commemorating their mission. Photo Credit: (NASA/Paul E. Alers)

  2. AmeriFlux US-SCg Southern California Climate Gradient - Grassland

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goulden, Mike

    This is the AmeriFlux version of the carbon flux data for the site US-SCg Southern California Climate Gradient - Grassland. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a grassland that was historically dominated by exotic annuals and that underwent restoration with a focus on native bunch grasses in the 2010s. The site has historically burned every 10-20 years, with a wildfire in October 2007. The restoration involved several yearsmore » of mowing and herbicide application to suppress exotics followed by dense planting of Nasella bunch grasses.« less

  3. Cultural Competency in Nursing Research.

    PubMed

    Cope, Diane G

    2015-05-01

    According to data from the U.S. Census Bureau (2010), the demographics of the United States will change dramatically in the next 50 years. Non-Caucasians will more than double from 116.2 million in 2012 to 241.3 million by 2060, representing 57% of the U.S. population (U.S. Census Bureau, 2010). The Asian population also is expected to double in the next five years and comprise 8% of the U.S. population (U.S. Census Bureau, 2012). The United States also is becoming an aging population. By 2060, about one in five residents will be aged 65 years and older (U.S. Census Bureau, 2012). Individuals aged 85 years and older will more than triple to 18.2 million and represent 4% of the U.S. population (U.S. Census Bureau, 2012). 
.

  4. Cost-benefit analysis of first-generation antihistamines in the treatment of allergic rhinitis.

    PubMed

    Sullivan, Patrick W; Follin, Sheryl L; Nichol, Michael B

    2004-01-01

    The majority of individuals with allergic rhinitis in the US take first-generation antihistamines (FGAs). Although FGAs have been proven effective in alleviating allergic rhinitis symptoms, they have been associated with an increased risk of motor vehicle, aviation and occupational injuries and deaths, reduced productivity and impaired learning. The objective of this analysis was to quantify the total costs and benefits of FGA use in the US from the societal perspective. We used a decision-analytic model to quantify the annual societal costs and benefits of treatment with FGAs compared with the hypothetical alternative of no treatment for the population of individuals with allergic rhinitis and taking FGAs in the US in 2001. The benefit associated with FGA use was estimated using the willingness-to-pay framework and projected to the US population using published estimates of the prevalence of allergic rhinitis. The costs of FGA-associated sedation included lost productivity and the direct and indirect cost of unintentional injuries (including motor vehicle, occupational, public and home injuries and fatalities). The incidence of injuries and fatalities associated with FGA use was estimated using the risk of injury attributable to the sedentary effects of FGAs in the allergic rhinitis population. To evaluate uncertainty in the model assumptions, a probabilistic sensitivity analysis was conducted using Bayesian second-order Monte Carlo simulation. Costs and benefits are expressed in 2001 US dollars, using a 3% discount rate. Based on current utilisation, the total societal benefit (95% credible interval) associated with the use of FGAs for the treatment of allergic rhinitis was US 7.7 billion dollars (US 1.3 billion dollars to US 21 billion dollars). The societal cost of purchasing FGAs was only US 697 million dollars. However, the societal cost of FGA-associated sedation was US 11.3 billion dollars (US 2.4 billion dollars to US 50.8 billion dollars). The annual societal net benefit of FGA use for the treatment of allergic rhinitis in the US was -US4.2 billion dollars (-US 36 billion dollars to +US 0.296 billion dollars). The net benefit was negative in 97% of the 10,000 Monte Carlo simulations. The societal benefits of FGA use in alleviating the symptoms of allergic rhinitis are significant. However, based on the assumptions, probability distributions and parameter estimate ranges used in the current model, it is very likely that the costs associated with sedation exceed the benefits of FGA use in the US. The cost of FGA-associated sedation is comparable to estimates of the cost of all medical care expenditures on respiratory conditions in the US (US 12.1 billion dollars to US 31.3 billion dollars) [1996 values] and provides compelling evidence of the economic burden of sedation associated with FGA use.

  5. Contact Us

    Science.gov Websites

    and in partnership with the U.S. Departments of Agriculture, Commerce, Defense, Education, Housing and United States Advisory Council on Historic Preservation logo U.S. Department of Agriculture logo U.S

  6. Neural Tube Defects

    MedlinePlus

    ... Join us on Facebook Follow us on Twitter Instagram: behind the scenes Our research Research grants Prematurity ... Join us on Facebook Follow us on Twitter Instagram: behind the scenes Research & Professionals Our research Research ...

  7. Post-introduction economic evaluation of pneumococcal conjugate vaccination in Ecuador, Honduras, and Paraguay.

    PubMed

    Constenla, Dagna O

    2015-11-01

    A decision-analytic model was constructed to evaluate the economic impact of post-introduction pneumococcal conjugate vaccine (PCV) programs in Ecuador, Honduras, and Paraguay from the societal perspective. Hypothetical birth cohorts were followed for a 20-year period in each country. Estimates of disease burden, vaccine effectiveness, and health care costs were derived from primary and secondary data sources. Costs were expressed in 2014 US$. Sensitivity analyses were performed to assess the impact of model input uncertainties. Over the 20 years of vaccine program implementation, the health care costs per case ranged from US$ 764 854 to more than US$ 1 million. Vaccination prevented more than 50% of pneumococcal cases and deaths per country. At a cost of US$ 16 per dose, the cost per disability-adjusted life year (DALY) averted for the 10-valent PCV (PCV10) and the 13-valet PCV (PCV13) ranged from US$ 796 (Honduras) to US$ 1 340 (Ecuador) and from US$ 691 (Honduras) to US$ 1 166 (Ecuador) respectively. At a reduced price (US$ 7 per dose), the cost per DALY averted ranged from US$ 327 (Honduras) to US$ 528 (Ecuador) and from US$ 281 (Honduras) to US$ 456 (Ecuador) for PCV10 and PCV13 respectively. Several model parameters influenced the results of the analysis, including vaccine price, vaccine efficacy, disease incidence, and costs. The economic impact of post-introduction PCV needs to be assessed in a context of uncertainty regarding changing antibiotic resistance, herd and serotype replacement effects, differential vaccine prices, and government budget constraints.

  8. Application of a Biotin Functionalized QD Assay for Determining Available Binding Sites on Electrospun Nanofiber Membrane

    DTIC Science & Technology

    2011-01-01

    Dawn.Nida@us.army.mil) Joshua Magnone (Joshua.Magnone@us.army.mil) Andre Senecal (Andy.Senecal@us.army.mil) ISSN 1477-3155 Article type Research Submission...Dawn.Nida@us.army.mil; Joshua Magnone - Joshua.Magnone@us.army.mil; Andre Senecal - Andy.Senecal@us.army.mil *Corresponding Author 2...Biol Eng 2007, 1:doi10.1186/1754-1611-1-2. 12. Senecal A, Magnone J, Marek P, Senecal K: Development of functional nanofibrous membrane assemblies

  9. U.S. Economic Strategy in Shaping Mexico - Living Happily Ever NAFTA.

    DTIC Science & Technology

    1998-05-09

    DOCTRINE IN THE HOUSE? 21 A U.S. Peso Crisis? 21 U.S. Promotion of Labor Reform 24 v U.S. STRATEGY - LINKING ENDS, WAYS AND MEANS 26 CONCLUSION...part to devaluation of the peso . Percentage changes calculated in local currency- Merchandise trade 5 Source: U.S. Department of Commerce and U.S...Mexico’s economic or political stability. A similar rationale can be applied to understanding the motive for U.S. assistance during the Peso Crisis of

  10. Bigfoot or Big Mistake: Is CBP’s Expanding Footprint Helping or Hurting Homeland Security

    DTIC Science & Technology

    2017-03-31

    message. Since its founding in 1789, the U.S. Customs Service has guarded the U.S. ports of entry and collected tariffs on goods coming into the United...a nation’s innocence. Immediately after the attacks, Commissioner Bonner knew that a change in the mission of U.S. Customs Service was essential to...Department of Homeland Security (DHS). This included the U.S. Customs Service , U.S. Border Patrol, and U.S. Coast Guard. Title IV of the Act created

  11. International energy indicators

    NASA Astrophysics Data System (ADS)

    Rosoi, E., Jr.

    1982-01-01

    Data are presented under the following headings: world crude oil production, OPEC crude oil productive capacity; world crude oil and refined product inventory levels; and oil consumption in the OECD countries. The USSR crude oil production and exports; free world and US nuclear electricity generation; US domestic oil supply; US gross imports of crude oil and products; landed cost of Saudi crude, current and 1974 dollars; US coal trade; US natural gas trade; summary of US merchandise trade; and energy/GNP ratio data are also included.

  12. American Medical Society for Sports Medicine recommended sports ultrasound curriculum for sports medicine fellowships.

    PubMed

    Finnoff, Jonathan T; Berkoff, David; Brennan, Fred; DiFiori, John; Hall, Mederic M; Harmon, Kimberly; Lavallee, Mark; Martin, Sean; Smith, Jay; Stovak, Mark

    2015-01-01

    The following sports ultrasound (SPORTS US) curriculum is a revision of the curriculum developed by the American Medical Society for Sports Medicine (AMSSM) in 2010. Several changes have been made to the curriculum with the primary aim of providing a pathway by which a sports medicine fellow can obtain sufficient SPORTS US training to become proficient in the core competencies of SPORTS US. The core competencies of SPORTS US are outlined in the learning objectives section of this document. The term "SPORTS US" was purposefully chosen rather than "musculoskeletal ultrasound" (MSK US) because it was recognized by the panel that the evolving field of SPORTS US encompasses non-MSK applications of ultrasound such as the FAST examination (focused assessment with sonography for trauma). Although the SPORTS US core competencies in this curriculum are all MSK in nature, they represent the minimum SPORTS US knowledge a sports medicine fellow should acquire during fellowship. However, additional training in more advanced MSK and non-MSK applications of ultrasound can be provided at the fellowship director's discretion. Completion of this SPORTS US curriculum fulfills the American Institute of Ultrasound in Medicine's (AIUM) requirements to perform an MSK US examination and the prerequisites for the American Registry for Diagnostic Medical Sonography's (ARDMS) MSK sonography certification examination.

  13. Tankers in US waters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stewart, R.J.

    About 200 US flag tankers operate between US ports; the import trade consists of 30-40 more US tankers and 600-700 foreign tankers. US ships have 50% as many spills per port call as Liberian tankers and 20-33% as many as foreign tankers as a whole. There is mounting evidence that ships are prone to have a rather constant number of spills per year irrespective of variations in port call exposure. When spill incidence is measured per ship time, the US tanker margin over foreign fleets is only 2-3 instead of 3-6. For 1973-1975, 76% of all US tanker spills weremore » <100 gal, compared with 65% of all flag of convenience spills. The probability of no tanker losses in a one-year period in US waters is only 0.22. One-half the losses can be expected to occur in conditions favorable to a spill in coastal waters. In any given year, the US tanker fleet of 235 vessels >1000 gross registered tonnage can be expected to have about 100 spills in US waters, while foreign flag ships contribute another 250 spills. The largest US tanker spill in a one-year period is <5000 gal; the median value for the largest spill from foreign tankers is closer to 50,000-100,000 gal.« less

  14. Scheduling a C-Section

    MedlinePlus

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  15. 76 FR 40745 - In the Matter of Certain Light-Emitting Diodes and Products Containing the Same; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...Notice is hereby given that two complaints were filed with the U.S. International Trade Commission on June 3, 2011, under section 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of OSRAM GmbH of Germany. Both complaints allege violations of section 337 based upon the importation into the United States, the sale for importation, and the sale within the United States after importation of certain lighting-emitting diodes and products containing same by reason of infringement of certain claims of U.S. Patents. The first complaint asserts U.S. Patent No. 6,812,500 (``the `500 patent''); U.S. Patent No. 7,078,732 (``the `732 patent''); U.S. Patent No. 7,126,162 (``the `162 patent''); U.S. Patent No. 7,345,317 (``the `317 patent''); U.S. Patent No. 7,629,621 (``the `621 patent''); U.S. Patent No. 6,459,130 (``the `130 patent''); U.S. Patent No. 6,927,469 (``the `469 patent''); U.S. Patent No. 7,199,454 (``the `454 patent''); and U.S. Patent No. 7,427,806 (``the `806 patent''). The second complaint asserts U.S. Patent No. 6,849,881 (``the `881 patent''); U.S. Patent No. 6,975,011 (``the `011 patent''); U.S. Patent No. 7,106,090 (``the `090 patent''); U.S. Patent No. 7,151,283 (``the `283 patent''); and U.S. Patent No. 7,271,425 (``the `425 patent'') as well as the `500 patent, `732 patent, `162 patent, `621 patent, `130 patent, `469 patent, and `454 patent. Each complaint further alleges that an industry in the United States exists as required by subsection (a)(2) of section 337. The complainant requests that the Commission institute the two investigations and, after the investigation, issue an exclusion order and cease and desist orders. Letters regarding the possible consolidation of investigations stemming from these complaints were received on June 21, June 22, and June 29, 2011.

  16. 76 FR 40746 - In the Matter of Certain Light-Emitting Diodes and Products Containing Same; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...Notice is hereby given that two complaints were filed with the U.S. International Trade Commission on June 3, 2011, under section 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of OSRAM GmbH of Germany. Both complaints allege violations of section 337 based upon the importation into the United States, the sale for importation, and the sale within the United States after importation of certain light-emitting diodes and products containing same by reason of infringement of certain claims of U.S. Patents. The first complaint asserts U.S. Patent No. 6,812,500 (``the `500 patent''); U.S. Patent No. 7,078,732 (``the `732 patent''); U.S. Patent No. 7,126,162 (``the `162 patent''); U.S. Patent No. 7,345,317 (``the `317 patent''); U.S. Patent No. 7,629,621 (``the `621 patent''); U.S. Patent No. 6,459,130 (``the `130 patent''); U.S. Patent No. 6,927,469 (``the `469 patent''); U.S. Patent No. 7,199,454 (``the `454 patent''); and U.S. Patent No. 7,427,806 (``the `806 patent''). The second complaint asserts U.S. Patent No. 6,849,881 (``the `881 patent''); U.S. Patent No. 6,975,011 (``the `011 patent''); U.S. Patent No. 7,106,090 (``the `090 patent''); U.S. Patent No. 7,151,283 (``the `283 patent''); and U.S. Patent No. 7,271,425 (``the `425 patent'') as well as the `500 patent, `732 patent, `162 patent, `621 patent, `130 patent, `469 patent, and `454 patent. Each complaint further alleges that an industry in the United States exists as required by subsection (a)(2) of section 337. The complainant requests that the Commission institute the two investigations and, after the investigation, issue an exclusion order and cease and desist orders. Letters regarding the possible consolidation of investigations stemming from these complaints were received on June 21, June 22, and June 29, 2011.

  17. Reinstatement after human feature-positive discrimination learning.

    PubMed

    Franssen, Mathijs; Claes, Nathalie; Vervliet, Bram; Beckers, Tom; Hermans, Dirk; Baeyens, Frank

    2017-04-01

    In two experiments, using an online conditioned suppression task, we investigated the possibility of reinstatement of extinguished feature-target compound presentations after sequential feature-positive discrimination training in humans. Furthermore, given a hierarchical account of Pavlovian modulation (e.g., Bonardi, 1998; Bonardi and Jennings, 2009), we predicted A-US reinstatement to be stronger than US-only reinstatement. In Experiment 1, participants learned a sequential feature-positive discrimination (X→A + |A - ), which was subsequently extinguished (X→A - ). During the following reinstatement phase, group US-only received US-only presentations (not signalled), group A-US received A-US presentations, and the Control group received exposure to the context, but no CSs or USs, for an equal amount of time. Reinstatement of differential X→A/A responding was observed in the US-only group but not in the Control or A-US groups. Although differential X→A/A responding was not significant in group A-US, responding to the X→A compound was significantly stronger compared to that in group US-only. Hence, it could be the case the group A-US showed stronger reinstatement, but that differential responding was abolished due to excitation gained by A. Experiment 2 was set up to circumvent the acquired excitation of A by testing transfer of the feature after A-US reinstatement to a different target, B. Participants acquired two discriminations, X→A/A and Y→B/B, of which X→A was then extinguished. Subsequently, group A-US received reinforced presentations of A during a reinstatement phase while group Control received exposure to the context. Final testing of the novel X→B compound was hypothesized to show higher responding in group A-US than in group Control, but findings of this approach were limited due to acquired equivalence and/or perceptual factors causing a secondary extinction effect. We conclude to have obtained clear evidence in favour of reinstatement of differential responding after human Feature-Positive discrimination training and subsequent compound extinction, but no evidence in favour of A-US presentations being a stronger trigger for reinstatement than are US-only presentations. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Cost Per Additional Responder Associated With Ixekizumab and Etanercept in the Treatment of Moderate-to-Severe Psoriasis.

    PubMed

    Feldman, Steven R; Foster, Shonda A; Zhu, Baojin; Burge, Russel; Al Sawah, Sarah; Goldblum, Orin M

    2017-12-01

    BACKGROUND: Newer psoriasis treatments can achieve greater levels of efficacy than older systemic therapies; however, current psoriasis costs are substantial. We sought to estimate costs per additional responder associated with ixekizumab and etanercept, versus placebo, using efficacy data from phase 3 clinical trials (UNCOVER-2 and UNCOVER-3). METHODS: In UNCOVER-2/UNCOVER-3, patients received subcutaneous placebo, etanercept 50 mg twice weekly (BIW), or ixekizumab one 80 mg injection every 2 weeks (Q2W) after a 160-mg starting dose. Twelve-week induction-phase Psoriasis Area and Severity Index (PASI) 75, PASI 90, and PASI 100 response rates for ixekizumab, etanercept, and placebo were obtained from pooled data from the overall and United States (US) subgroup intention-to-treat (ITT) populations, and used to calculate numbers needed to treat (NNTs) to achieve one additional PASI 75, PASI 90, or PASI 100 response for ixekizumab Q2W and etanercept BIW versus placebo. Twelve-week drug costs per patient were calculated based on the UNCOVER-2/UNCOVER-3 dosing schedule and wholesale acquisition costs. Mean costs per additional responder for PASI 75, PASI 90, and PASI 100 for each treatment versus placebo were calculated for pooled UN-COVER-2/UNCOVER-3 overall and US subgroup ITT populations. RESULTS: Pooled overall ITT population: costs per additional PASI 75, PASI 90, or PASI 100 responder were US $37,540, US $46,299, or US $80,710 for ixekizumab Q2W and US $57,533, US $120,720, or US $404,695 for etanercept BIW, respectively. US subgroup ITT population: costs per additional PASI 75, PASI 90, or PASI 100 responder were US $38,165, US $49,740, or US $93,536 for ixekizumab Q2W and US $69,580, US $140,881, or US $631,875 for etanercept BIW, respectively. CONCLUSIONS: Twelve-week costs per additional responder were lower for ixekizumab Q2W than for etanercept BIW across all levels of clearance (PASI 75, PASI 90, and PASI 100) in the pooled UNCOVER-2/UNCOVER-3 overall and US subgroup ITT populations.

  19. 76 FR 16458 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. EPR... of the Safety Evaluation Report (SER) with open items associated with U.S. EPR Design Control...

  20. 76 FR 28006 - Proposed Authorization Under the U.S. Army Corps of Engineers Nationwide Permit Program of U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... DEPARTMENT OF DEFENSE Department of the Army, Corps of Engineers Proposed Authorization Under the U.S. Army Corps of Engineers Nationwide Permit Program of U.S. Department of Agriculture, Natural Resources Conservation Service, Categorical Exclusions AGENCY: U.S. Army Corps of Engineers, DoD. ACTION...

  1. Ensuring Academic Standards in US Higher Education

    ERIC Educational Resources Information Center

    Dill, David D.

    2014-01-01

    The most recent research on college-student learning in the US by respected scholars such as Richard Arum, Josipa Roksa, and Ernest Pascarella suggests that the nation's means of ensuring academic standards in US colleges and universities are not working effectively. Like US K-12 education and health care, the US higher education system is…

  2. Navy POD

    Science.gov Websites

    Naval History Contact Us Command Addresses (SNDL) FAQ Leadership Secretary of the Navy Under Secretary Chiefs of Staff Defense.gov U.S. Army U.S. Air Force U.S. Marine Corps U.S. Coast Guard Naval History inclusivity and pluralism. This Day in Naval History - May 27 History RSS Story Number: NNS020131-28 Release

  3. 75 FR 63811 - The U.S. Travel & Tourism Advisory Board: Information-Gathering Session of the U.S. Travel and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... matters relating to the U.S. travel and tourism industries. Date: October 26, 2010. Time: 9 a.m. (PT... DEPARTMENT OF COMMERCE International Trade Administration The U.S. Travel & Tourism Advisory Board: Information-Gathering Session of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade...

  4. 75 FR 16438 - U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... Tourism Advisory Board (Board) will hold a meeting to discuss topics related to the travel and tourism...

  5. 31 CFR 800.226 - U.S. business.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false U.S. business. 800.226 Section 800.226... FOREIGN PERSONS Definitions § 800.226 U.S. business. The term U.S. business means any entity, irrespective... subsidiary is a U.S. business. Corporation A and its branch or subsidiary is each also a foreign person...

  6. 31 CFR 800.226 - U.S. business.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false U.S. business. 800.226 Section 800.226... FOREIGN PERSONS Definitions § 800.226 U.S. business. The term U.S. business means any entity, irrespective... subsidiary is a U.S. business. Corporation A and its branch or subsidiary is each also a foreign person...

  7. 31 CFR 800.226 - U.S. business.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false U.S. business. 800.226 Section 800.226... FOREIGN PERSONS Definitions § 800.226 U.S. business. The term U.S. business means any entity, irrespective... subsidiary is a U.S. business. Corporation A and its branch or subsidiary is each also a foreign person...

  8. Nothing about Us without Us: Art Education's Disservice to Disabled People

    ERIC Educational Resources Information Center

    Derby, John

    2013-01-01

    The disability rights movement slogan, "nothing about us without us," has been trumpeted with such fervor that it is nearly a cliché. However, readers have never seen this phrase in "Studies in Art Education." Almost "nothing about us" has appeared in the pages of "Studies" or other major journals in the…

  9. Low-intensity focused ultrasound (LIFU)-induced acoustic droplet vaporization in phase-transition perfluoropentane nanodroplets modified by folate for ultrasound molecular imaging.

    PubMed

    Liu, Jianxin; Shang, Tingting; Wang, Fengjuan; Cao, Yang; Hao, Lan; Ren, JianLi; Ran, Haitao; Wang, Zhigang; Li, Pan; Du, Zhiyu

    2017-01-01

    The commonly used ultrasound (US) molecular probes, such as targeted microbubbles and perfluorocarbon emulsions, present a number of inherent problems including the conflict between US visualization and particle penetration. This study describes the successful fabrication of phase changeable folate-targeted perfluoropentane nanodroplets (termed FA-NDs), a novel US molecular probe for tumor molecular imaging with US. Notably, these FA-NDs can be triggered by low-intensity focused US (LIFU) sonication, providing excellent US enhancement in B-mode and contrast-enhanced US mode in vitro. After intravenous administration into nude mice bearing SKOV3 ovarian carcinomas, 1,1'-dioctadecyl-3,3,3',3' -tetramethylindotricarbocya-nine iodide-labeled FA-NDs were found to accumulate in the tumor region. FA-NDs injection followed by LIFU sonication exhibited remarkable US contrast enhancement in the tumor region. In conclusion, combining our elaborately developed FA-NDs with LIFU sonication provides a potential protocol for US molecular imaging in folate receptor-overexpressing tumors.

  10. Low-intensity focused ultrasound (LIFU)-induced acoustic droplet vaporization in phase-transition perfluoropentane nanodroplets modified by folate for ultrasound molecular imaging

    PubMed Central

    Liu, Jianxin; Shang, Tingting; Wang, Fengjuan; Cao, Yang; Hao, Lan; Ren, JianLi; Ran, Haitao; Wang, Zhigang; Li, Pan; Du, Zhiyu

    2017-01-01

    The commonly used ultrasound (US) molecular probes, such as targeted microbubbles and perfluorocarbon emulsions, present a number of inherent problems including the conflict between US visualization and particle penetration. This study describes the successful fabrication of phase changeable folate-targeted perfluoropentane nanodroplets (termed FA-NDs), a novel US molecular probe for tumor molecular imaging with US. Notably, these FA-NDs can be triggered by low-intensity focused US (LIFU) sonication, providing excellent US enhancement in B-mode and contrast-enhanced US mode in vitro. After intravenous administration into nude mice bearing SKOV3 ovarian carcinomas, 1,1′-dioctadecyl-3,3,3′,3′ -tetramethylindotricarbocya-nine iodide-labeled FA-NDs were found to accumulate in the tumor region. FA-NDs injection followed by LIFU sonication exhibited remarkable US contrast enhancement in the tumor region. In conclusion, combining our elaborately developed FA-NDs with LIFU sonication provides a potential protocol for US molecular imaging in folate receptor-overexpressing tumors. PMID:28184161

  11. Prospective cohort study of ultrasound-ultrasound and ultrasound-MR enterography agreement in the evaluation of pediatric small bowel Crohn disease.

    PubMed

    Dillman, Jonathan R; Smith, Ethan A; Sanchez, Ramon; DiPietro, Michael A; Dehkordy, Soudabeh Fazeli; Adler, Jeremy; DeMatos-Maillard, Vera; Khalatbari, Shokoufeh; Davenport, Matthew S

    2016-04-01

    There is a paucity of published literature describing ultrasound (US)-US and US-MR enterography (MRE) inter-radiologist agreement in pediatric small bowel Crohn disease. To prospectively assess US-US and US-MRE inter-radiologist agreement in pediatric small bowel Crohn disease. Institutional Review Board approval and informed consent/assent were obtained for this HIPAA-compliant prospective cohort study of children with newly diagnosed distal small bowel Crohn disease (July 2012 to December 2014). Enrolled subjects (n = 29) underwent two small bowel US examinations performed by blinded independent radiologists both before and at multiple time points after initiation of medical therapy (231 unique US examinations, in total); 134 US examinations were associated with concurrent MRE. The MRE examination was interpreted by a third blinded radiologist. The following was documented on each examination: involved length of ileum (cm); maximum bowel wall thickness (mm); amount of bowel wall and mesenteric Doppler signal, and presence of stricture, penetrating disease and/or abscess. Inter-radiologist agreement was assessed with single-measure, three-way, mixed-model intra-class correlation coefficients (ICC) and prevalence-adjusted, bias-adjusted kappa statistics (κ). Numbers in brackets are 95% confidence intervals. Ultrasound-US agreement was moderate for involved length (ICC: 0.41 [0.35-0.49]); substantial for maximum bowel wall thickness (ICC: 0.67 [0.64-0.70]); moderate for bowel wall Doppler signal (ICC: 0.53 [0.48-0.59]); slight for mesenteric Doppler signal (ICC: 0.25 [0.18-0.42]), and moderate to almost perfect for stricture (κ: 0.54), penetrating disease (κ: 0.80), and abscess (κ: 0.96). US-MRE agreement was moderate for involved length (ICC: 0.42 [0.37-0.49]); substantial for maximum bowel wall thickness (ICC: 0.66 [0.65-0.69]), and substantial to almost perfect for stricture (κ: 0.61), penetrating disease (κ: 0.72) and abscess (κ: 0.88). Ultrasound-US agreement was similar to US-MRE agreement for assessing pediatric small bowel Crohn disease. Discrepancies in US-US and US-MRE reporting question the utility of US as an accurate, reproducible radiologic biomarker for assessing response to medical therapy and disease-related complications.

  12. What Can We Learn from Hugoniot Temperature as a Function of Shock Velocity?

    NASA Astrophysics Data System (ADS)

    LI, M.; Jeanloz, R.

    2015-12-01

    Shock-wave experiments traditionally rely on impact techniques, whereby measured shock velocity (US) can be related to material velocity (up), determined from the impact velocity (= 2up for a symmetric impact), and resulting in the empirically observed linear US-up equation of state: US = c0 + s up. Modern experiments relying on laser-driven compression have the advantage of reaching higher pressures than laboratory impact experiments, but up is typically not determined; instead, Hugoniot temperature (TH) and shock velocity are more readily measured. Assuming a linear US-up equation of state and that the Grüneisen parameter has the volume dependence g(V) = g0 (V/V0), measurements of the Hugoniot temperature as a function of shock velocity provide constraints on the specific heat along the Hugoniot CVH(US) = V0 f(US)[c0 g0 TH - s US dTH/dUS]-1 where the Walsh-Christian (1955) function f(US) = - (US - c0)2 US/(V0 s c0) = TH dSH/dVH gives the entropy change along the Hugoniot (subscripts 0 and H indicate zero-pressure and Hugoniot states, respectively). In this sense, TH(US) measurements are similar to calorimetry experiments. If specific heat and Grüneisen parameter are determined independently (e.g., from wave-velocity measurements and experiments on porous samples), the TH(US) analog to the linear US-up equation of state is TH(US) = {T0 exp(g0 /s) - ò[V0 c0 f(x)/(s x CV)] exp[c0 g0 /(s x)] dx} exp[- c0 g0 /(s US)] where the integration is from x = c0 to x = US. In addition, experiments can be considered with: 1) different initial volume, as in a porous sample; 2) different initial internal energy, as in a sample heated at constant volume; and 3) different initial volume and internal energy, as in a sample initially heated at ambient pressure. From these four initial states, we get four different Hugoniot curves, and can also consider the effect of phase transition latent heat. Temperature as a function of shock velocity may thus be benefit the analysis of melting and other phase transitions with small volume change and finite latent heat.

  13. ThinkFirst National Injury Prevention Foundation

    MedlinePlus

    ... Our Board of Directors Awards & Recognition Contact Us Shop With Us Support Us Login Cart Injury Prevention ... Proud Member of the Combined Federal Campaign #35749 Shop & Support Us! Shop at smile.amazon.com and ...

  14. Contact Us | DOepatents

    Science.gov Websites

    ORCID Search Authors Patent Number: Patent Application Number: Contract Number: Subject: Lab/Technology us by phone Phone Phone (865) 241-5275 Contact us in writing Mail U.S. Department of Energy Office of

  15. The comparative cost-effectiveness of colorectal cancer screening using faecal immunochemical test vs. colonoscopy.

    PubMed

    Wong, Martin C S; Ching, Jessica Y L; Chan, Victor C W; Sung, Joseph J Y

    2015-09-04

    Faecal immunochemical tests (FITs) and colonoscopy are two common screening tools for colorectal cancer(CRC). Most cost-effectiveness studies focused on survival as the outcome, and were based on modeling techniques instead of real world observational data. This study evaluated the cost-effectiveness of these two tests to detect colorectal neoplastic lesions based on data from a 5-year community screening service. The incremental cost-effectiveness ratio (ICER) was assessed based on the detection rates of neoplastic lesions, and costs including screening compliance, polypectomy, colonoscopy complications, and staging of CRC detected. A total of 5,863 patients received yearly FIT and 4,869 received colonoscopy. Compared with FIT, colonoscopy detected notably more adenomas (23.6% vs. 1.6%) and advanced lesions or cancer (4.2% vs. 1.2%). Using FIT as control, the ICER of screening colonoscopy in detecting adenoma, advanced adenoma, CRC and a composite endpoint of either advanced adenoma or stage I CRC was US$3,489, US$27,962, US$922,762 and US$23,981 respectively. The respective ICER was US$3,597, US$439,513, -US$2,765,876 and US$32,297 among lower-risk subjects; whilst the corresponding figure was US$3,153, US$14,852, US$184,162 and US$13,919 among higher-risk subjects. When compared to FIT, colonoscopy is considered cost-effective for screening adenoma, advanced neoplasia, and a composite endpoint of advanced neoplasia or stage I CRC.

  16. All-Cause, Stroke/Systemic Embolism-, and Major Bleeding-Related Health-Care Costs Among Elderly Patients With Nonvalvular Atrial Fibrillation Treated With Oral Anticoagulants.

    PubMed

    Deitelzweig, Steve; Luo, Xuemei; Gupta, Kiran; Trocio, Jeffrey; Mardekian, Jack; Curtice, Tammy; Hlavacek, Patrick; Lingohr-Smith, Melissa; Menges, Brandy; Lin, Jay

    2018-05-01

    In this study, all-cause, stroke/systemic embolism (SE)-related, and major bleeding (MB)-related health-care costs among elderly patients with nonvalvular atrial fibrillation (NVAF) initiating treatment with different oral anticoagulants (OACs) were compared. Patients ≥65 years of age initiating OACs, including apixaban, rivaroxaban, dabigatran, and warfarin, were identified from the Humana Research Database between January 1, 2013, and September 30, 2015. Propensity score matching was used to separately match the different OAC cohorts with the apixaban cohort. All-cause health-care costs and stroke/SE-related and MB-related medical costs per patient per month (PPPM) were compared using generalized linear or 2-part regression models. Compared to apixaban, rivaroxaban was associated with significantly higher all-cause health-care costs (US$2234 vs US$1846 PPPM, P < .001) and MB-related medical costs (US$106 vs US$47 PPPM, P < .001), dabigatran was associated with significantly higher all-cause health-care costs (US$1980 vs US$1801 PPPM, P = .007), and warfarin was associated with significantly higher all-cause health-care costs (US$2386 vs US$1929 PPPM, P < .001), stroke/SE-related medical costs (US$42 vs US$18 PPPM, P < .001), and MB-related medical costs (US$132 vs US$51 PPPM, P < .001). Among elderly patients with NVAF, other OACs were associated with higher all-cause health-care costs than apixaban.

  17. Money well spent: a comparison of hospital operating margin for laparoscopic and open colectomies.

    PubMed

    Koopmann, M C; Harms, B A; Heise, C P

    2007-10-01

    Cost analysis after laparoscopic colectomy has been examined, although reports evaluating the effects of laparoscopy on hospital operating margin are lacking. We compared several cost/revenue measures, including hospital operating margin, between open and laparoscopic colectomies at an academic center. Our cost-accounting database was queried for laparoscopic partial (LPC) and total colectomies (LTC), and open partial (OPC) and total colectomies (OTC) to analyze net revenue, total costs, and total hospital operating margin over a 4-year period. Laparoscopic and open colectomy cases were compared, with mean operating margin as the primary outcome. From July, 2002 through May, 2006, 842 patients were included for analysis with 138 undergoing laparoscopic colectomy. Net revenue was higher in the LTC group compared with open (US dollars 30,300 vs US dollars 26,800 [P = .02]), and lower in the LPC group (US dollars 15,300 vs US dollars 21,300 open [P < .0001]). Total costs were reduced in both the LPC and LTC groups compared with open [US dollars 11,700 vs US dollars 17,600 [P < .0001] and US dollars 18,000 vs US dollars 19,400 [P = .0019], respectively). LPC resulted in a similar HOM (US dollars 3,602) compared with OPC (US dollars 3,647; P = .35). LTC resulted in a higher HOM (US dollars 12,300) compared with OTC (US dollars 7,400; P = .02). LTC generates a significantly higher hospital operating margin than an OTC, although the margins are similar for LPC and OPC.

  18. Role of specimen US for predicting resection margin status in breast conserving therapy.

    PubMed

    Moschetta, M; Telegrafo, M; Introna, T; Coi, L; Rella, L; Ranieri, V; Cirili, A; Stabile Ianora, A A; Angelelli, G

    2015-01-01

    To assess the diagnostic accuracy of specimen ultrasound (US) for predicting resection margin status in women undergoing breast conserving therapy for US-detected cancer, having the histological findings as the reference standard. A total of 132 consecutive patients (age range, 34-87 years; mean, 51 years) underwent breast-conserving surgery for US-detected invasive breast cancer. All surgical specimens underwent US examination. The presence of lesion within the specimen and its distance from the specimen margins were assessed considering a threshold distance between the lesion and specimen margins of 10 mm. US findings were then compared with the pathological ones and specimen US. Sensitivity, specificity, diagnostic accuracy, positive (PPV) and negative predictive values (NPV) for predicting histological margin status were evaluated, having the histological findings as the reference standard. The histological examination detected invasive ductal carcinoma in 96/132 (73%) cases, invasive lobular carcinoma in 32/132 (24%), mucinous carcinoma in 4/132 (3%). The pathological margin analysis revealed 96/132 (73%) negative margins and 36 (27%) close/positive margins. US examination detected all 132 breast lesions within the surgical specimens. 110 (83%) negative margins and 22 (17%) positive margins were found on US. Sensitivity, specificity, diagnostic accuracy, PPV and NPV of 44%, 94%, 80%, 73% and 82%, respectively, were found for specimen US. Specimen US represents a time and cost saving imaging tool for evaluating the presence of US detected-breast lesion within surgical specimen and for predicting the histological margin status.

  19. Removal of polycyclic aromatic hydrocarbons (PAHs) from textile dyeing sludge by ultrasound combined zero-valent iron/EDTA/Air system.

    PubMed

    Man, Xiaoyuan; Ning, Xun-An; Zou, Haiyuan; Liang, Jieying; Sun, Jian; Lu, Xingwen; Sun, Jiekui

    2018-01-01

    This paper proposes a combined ultrasound (US) and zero-valent iron/EDTA/Air (ZEA) system to remove polycyclic aromatic hydrocarbons (PAHs) from textile dyeing sludge. The removal efficiencies of 16 PAHs using ZEA, US/Air (air injected into the US process), and US/ZEA treatments were investigated, together with the effects of various operating parameters. The enhanced mechanisms of US and the role of reactive oxygen species (ROS) in removing PAHs in the US/ZEA system were explored. Results showed that only 42.5% and 32.9% of ∑16 PAHs were removed by ZEA and US/Air treatments respectively, whereas 70.1% were removed by US/ZEA treatment, (with favorable operating conditions of 2.0 mM EDTA, 15 g/L ZVI, and 1.08 w/cm 3 ultrasonic density). The US/ZEA system could be used with a wide pH range. US led to synergistic improvement of PAHs removal in the ZEA system by enhancing sludge disintegration to release PAHs and promoting ZVI corrosion and oxygen activation. In the US/ZEA system, PAHs could be degraded by ROS (namely OH, O 2 - /HO 2 , and Fe(IV)) and adsorbed by ZVI, during which the ROS made the predominant contribution. This study provides important insights into the application of a US/ZEA system to remove PAHs from sludge. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. The comparative cost-effectiveness of colorectal cancer screening using faecal immunochemical test vs. colonoscopy

    PubMed Central

    Wong, Martin CS; Ching, Jessica YL; Chan, Victor CW; Sung, Joseph JY

    2015-01-01

    Faecal immunochemical tests (FITs) and colonoscopy are two common screening tools for colorectal cancer(CRC). Most cost-effectiveness studies focused on survival as the outcome, and were based on modeling techniques instead of real world observational data. This study evaluated the cost-effectiveness of these two tests to detect colorectal neoplastic lesions based on data from a 5-year community screening service. The incremental cost-effectiveness ratio (ICER) was assessed based on the detection rates of neoplastic lesions, and costs including screening compliance, polypectomy, colonoscopy complications, and staging of CRC detected. A total of 5,863 patients received yearly FIT and 4,869 received colonoscopy. Compared with FIT, colonoscopy detected notably more adenomas (23.6% vs. 1.6%) and advanced lesions or cancer (4.2% vs. 1.2%). Using FIT as control, the ICER of screening colonoscopy in detecting adenoma, advanced adenoma, CRC and a composite endpoint of either advanced adenoma or stage I CRC was US$3,489, US$27,962, US$922,762 and US$23,981 respectively. The respective ICER was US$3,597, US$439,513, -US$2,765,876 and US$32,297 among lower-risk subjects; whilst the corresponding figure was US$3,153, US$14,852, US$184,162 and US$13,919 among higher-risk subjects. When compared to FIT, colonoscopy is considered cost-effective for screening adenoma, advanced neoplasia, and a composite endpoint of advanced neoplasia or stage I CRC. PMID:26338314

  1. 39 CFR 1.1 - Establishment of the U.S. Postal Service.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...

  2. 39 CFR 1.1 - Establishment of the U.S. Postal Service.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...

  3. 76 FR 4739 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. EPR... 6 and Chapter 15 of the U.S. EPR Safety Evaluation Report (SER) with Open Items. The Subcommittee...

  4. 75 FR 82094 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on January 12, 2011, Room T-2B1, 11545 Rockville Pike...

  5. US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone Experiment

    DTIC Science & Technology

    2016-07-01

    ARL-TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance...TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone...National Robotics Engineering Center, Pittsburgh, PA Robert Dean, Terence Keegan, and Chip Diberardino General Dynamics Land Systems, Westminster

  6. 78 FR 65390 - Exemption From Licensing for Disposal of Low-Activity Radioactive Waste at the US Ecology Idaho...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ... Disposal of Low-Activity Radioactive Waste at the US Ecology Idaho Resource Conservation and Recovery Act..., Pennsylvania, at the US Ecology Idaho (USEI) Resource Conservation and Recovery Act (RCRA) Subtitle C disposal... from the US Ecology, Inc. (US Ecology), dated July 7, 2013 (ADAMS Accession No. ML13198A017), for...

  7. Climate Change and International Competition: the US Army in the Arctic Environment

    DTIC Science & Technology

    2015-05-21

    capabilities are evaluated within the domains of the current US doctrinal definition of Doctrine , Organization, Training, Materiel, Leadership and Education...environment. 15. SUBJECT TERMS US Army Cold Weather Doctrine ; US Army Arctic Operational Capability; ULO; Mission Command; Arctic Council; UNCLOS...capabilities are evaluated within the domains of the current US doctrinal definition of Doctrine , Organization, Training, Materiel, Leadership and

  8. The Manufacturing Industry

    DTIC Science & Technology

    2005-06-01

    South Korea Samsung Electronics, Suwon, South Korea US Embassy Country Brief, Beijing, China US Consulate General Brief, Hong Kong Joint US... employees . Innovation, leveraged by science and technology (S&T), has created opportunities within the manufacturing sector. This paper summarizes the...productivity, both per hour and per employee . This fact has enabled the US to maintain a labor cost advantage despite the higher wages/benefits paid to US

  9. 77 FR 58084 - Endangered and Threatened Wildlife and Plants; 90-Day Findings on Petitions To Delist U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ...-0077; 4500030115] Endangered and Threatened Wildlife and Plants; 90-Day Findings on Petitions To Delist... to remove the U.S. captive-bred and U.S. captive populations of three antelope species, the scimitar... delisting the U.S. captive animals or U.S. captive-bred members of these species may be warranted. Therefore...

  10. 7 CFR 51.1001 - U.S. Combination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) In this grade the U.S. No. 1 limes shall meet the color requirements of the U.S. No. 1 grade and the U.S. No. 2 limes shall meet the color requirements of the U.S. No. 2 grade: Provided, That lots of... designated as “U.S. Combination, Mixed Color”: And provided further, That lots of limes which fail to meet...

  11. 7 CFR 51.1001 - U.S. Combination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) In this grade the U.S. No. 1 limes shall meet the color requirements of the U.S. No. 1 grade and the U.S. No. 2 limes shall meet the color requirements of the U.S. No. 2 grade: Provided, That lots of... designated as “U.S. Combination, Mixed Color”: And provided further, That lots of limes which fail to meet...

  12. U.S. Cybersecurity Defense Assessment

    DTIC Science & Technology

    2013-03-01

    Government . The U.S. Army War College is accredited by the Commission on Higher Education of the Middle States Association of Colleges and...progression of America’s cybersecurity defense policies and the subsequent Federal agency roles which have developed within the U.S. government ...of the Army, Department of Defense, or the U.S. Government . U.S. Army War College CARLISLE BARRACKS, PENNSYLVANIA 17013 Abstract

  13. 17 CFR Appendix B to Part 43 - Enumerated Physical Commodity Contracts and Other Contracts

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Physical Commodity Contracts and Other Contracts Enumerated Physical Commodity Contracts Agriculture ICE Futures U.S. Cocoa ICE Futures U.S. Coffee C Chicago Board of Trade Corn ICE Futures U.S. Cotton No. 2 ICE... Trade Soybean Oil ICE Futures U.S. Sugar No. 11 ICE Futures U.S. Sugar No. 16 Chicago Board of Trade...

  14. 17 CFR Appendix B to Part 43 - Enumerated Physical Commodity Contracts and Other Contracts

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Commodity Contracts and Other Contracts Enumerated Physical Commodity Contracts Agriculture ICE Futures U.S. Cocoa ICE Futures U.S. Coffee C Chicago Board of Trade Corn ICE Futures U.S. Cotton No. 2 ICE Futures U... Soybean Oil ICE Futures U.S. Sugar No. 11 ICE Futures U.S. Sugar No. 16 Chicago Board of Trade Wheat...

  15. 75 FR 59718 - US Search, Inc. And US Search, LLC; Analysis of Proposed Consent Order to Aid Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... FEDERAL TRADE COMMISSION [File No. 102 3131] US Search, Inc. And US Search, LLC; Analysis of... written comments electronically or in paper form. Comments should refer to``US Search, Inc., File No. 101... this Notice appears at ( http://www.regulations.gov/search/index.jsp ), you may also file an electronic...

  16. 76 FR 69271 - Notice of Inquiry; U.S. Inland Containerized Cargo Moving Through Canadian and Mexican Seaports

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... incentivize container cargo to shift from U.S. West Coast ports to those located in Canada and Mexico. These... FEDERAL MARITIME COMMISSION [Docket No. 11-19] Notice of Inquiry; U.S. Inland Containerized Cargo... containerized cargo destined for U.S. inland points from U.S. to Canadian and Mexican seaports. DATES: Comments...

  17. 32 CFR 842.121 - Referring a claim to the US Attorney.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Referring a claim to the US Attorney. 842.121... to the US Attorney. Only HQ USAF/JACC authorizes referral of a claim to the US Attorney. The base SJA...-case basis, HQ USAF/JACC will authorize referral of a case to the US Attorney by telephone. ...

  18. Environmental Public Health Research at the U.S. Environmental Protection Agency – Addressing Community Exposures and Outcomes from One Researcher’s Perspective

    EPA Science Inventory

    The U.S. Environmental Protection Agency’s (U.S. EPA) mission is to protect human health and the environment. Those not familiar with U.S. EPA’s mission often do not realize that U.S. EPA is a public health agency. In this presentation, Dr. Danelle Lobdell will provid...

  19. 39 CFR 1.1 - Establishment of the U.S. Postal Service.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...

  20. 39 CFR 1.1 - Establishment of the U.S. Postal Service.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...

  1. 39 CFR 1.1 - Establishment of the U.S. Postal Service.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...

  2. Mortality among US-born and immigrant Hispanics in the US: effects of nativity, duration of residence, and age at immigration.

    PubMed

    Holmes, Julia S; Driscoll, Anne K; Heron, Melonie

    2015-07-01

    We examined the effects of duration of residence and age at immigration on mortality among US-born and foreign-born Hispanics aged 25 and older. We analyzed the National Health Interview Survey-National Death Index linked files from 1997-2009 with mortality follow-up through 2011. We used Cox proportional hazard models to examine the effects of duration of US residence and age at immigration on mortality for US-born and foreign-born Hispanics, controlling for various demographic, socioeconomic and health factors. Age at immigration included 4 age groups: <18, 18-24, 25-34, and 35+ years. Duration of residence was 0-15 and >15 years. We observed a mortality advantage among Hispanic immigrants compared to US-born Hispanics only for those who had come to the US after age 24 regardless of how long they had lived in the US. Hispanics who immigrated as youths (<18) did not differ from US-born Hispanics on mortality despite duration of residence. Findings suggest that age at immigration, rather than duration of residence, drives differences in mortality between Hispanic immigrants and the US-born Hispanic population.

  3. U.S. oil dependence 2014: Is energy independence in sight?

    DOE PAGES

    Greene, David L.; Liu, Changzheng

    2015-06-10

    The importance of reducing U.S. oil dependence may have changed in light of developments in the world oil market over the past two decades. Since 2005, increased domestic production and decreased oil use have cut U.S. import dependence in half. The direct costs of oil dependence to the U.S. economy are estimated under four U.S. Energy Information Administration Scenarios to 2040. The key premises of the analysis are that the primary oil market failure is the use of market power by OPEC and that U.S. economic vulnerability is a result of the quantity of oil consumed, the lack of readilymore » available, economical substitutes and the quantity of oil imported. Monte Carlo simulations of future oil market conditions indicate that the costs of U.S. oil dependence are likely to increase in constant dollars but decrease relative to U.S. gross domestic product unless oil resources are larger than estimated by the U.S. Energy Information Administration. In conclusion, reducing oil dependence therefore remains a valuable goal for U.S. energy policy and an important co-benefit of mitigating greenhouse gas emissions.« less

  4. Diagnosis of sub-centimetre breast lesions: combining BI-RADS-US with strain elastography and contrast-enhanced ultrasound-a preliminary study in China.

    PubMed

    Xiao, Xiaoyun; Jiang, Qiongchao; Wu, Huan; Guan, Xiaofeng; Qin, Wei; Luo, Baoming

    2017-06-01

    To compare the diagnostic efficacies of B-mode ultrasound (US), strain elastography (SE), contrast-enhanced ultrasound (CEUS) and the combination of these modalities for breast lesions <1 cm in size. Between January 2013 and October 2015, 203 inpatients with 209 sub-centimetre breast lesions categorised as BI-RADS-US (Breast Imaging Reporting and Data System for Ultrasound) 3-5 were included. US, SE and CEUS were performed to evaluate each lesion. The diagnostic performances of different ultrasonic modalities were compared. The diagnostic efficacies of BI-RADS-US and our re-rating systems were also compared. The pathology findings were used as the reference standard. The specificities of US, SE and CEUS for tumour differentiation were 17.4 %, 56.2 % and 86.0 %, respectively (P < 0.05); and the sensitivities were 100 %, 93.2 % and 93.2 % for US, SE and CEUS, respectively (P < 0.05). The area under the curve (AUC) of the receiver operating characteristic (ROC) curve was 0.867 for original BI-RADS-US, 0.882 for BI-RADS-US combined with only SE, 0.953 for BI-RADS-US combined with only CEUS and 0.924 for BI-RADS-US combined with both SE and CEUS. The best combination was BI-RADS-US combined with only CEUS. Evaluating sub-centimetre breast lesions with SE and CEUS could increase the diagnostic specificity while retaining high sensitivity compared with B-mode ultrasound. • Evaluating breast lesions with SE and CEUS could increase the diagnostic specificity • SE and CEUS offer alternatives to biopsy and possibly allow shorter-interval follow-ups • BI-RADS-US combined with CEUS exhibited the best diagnostic performance.

  5. Structural and Functional Dissection of Human Cytomegalovirus US3 in Binding Major Histocompatibility Complex Class I Molecules

    PubMed Central

    Lee, Sungwook; Yoon, Juhan; Park, Boyoun; Jun, Youngsoo; Jin, Mirim; Sung, Ha Chin; Kim, Ik-Hwan; Kang, Seongman; Choi, Eui-Ju; Ahn, Byung Yoon; Ahn, Kwangseog

    2000-01-01

    The human cytomegalovirus US3, an endoplasmic reticulum (ER)-resident transmembrane glycoprotein, forms a complex with major histocompatibility complex (MHC) class I molecules and retains them in the ER, thereby preventing cytolysis by cytotoxic T lymphocytes. To identify which parts of US3 confine the protein to the ER and which parts are responsible for the association with MHC class I molecules, we constructed truncated mutant and chimeric forms in which US3 domains were exchanged with corresponding domains of CD4 and analyzed them for their intracellular localization and the ability to associate with MHC class I molecules. All of the truncated mutant and chimeric proteins containing the luminal domain of US3 were retained in the ER, while replacement of the US3 luminal domain with that of CD4 led to cell surface expression of the chimera. Thus, the luminal domain of US3 was sufficient for ER retention. Immunolocalization of the US3 glycoprotein after nocodazole treatment and the observation that the carbohydrate moiety of the US3 glycoprotein was not modified by Golgi enzymes indicated that the ER localization of US3 involved true retention, without recycling through the Golgi. Unlike the ER retention signal, the ability to associate with MHC class I molecules required the transmembrane domain in addition to the luminal domain of US3. Direct interaction between US3 and MHC class I molecules could be demonstrated after in vitro translation by coimmunoprecipitation. Together, the present data indicate that the properties that allow US3 to be localized in the ER and bind MHC class I molecules are located in different parts of the molecule. PMID:11070025

  6. Combined of ultrasound irradiation with high hydrostatic pressure (US/HHP) as a new method to improve immobilization of dextranase onto alginate gel.

    PubMed

    Bashari, Mohanad; Abbas, Shabbar; Xu, Xueming; Jin, Zhengyu

    2014-07-01

    In this research work, dextranase was immobilized onto calcium alginate beads by the combination of ultrasonic irradiation and high hydrostatic pressure (US/HHP) treatments. Effects of US/HHP treatments on loading efficiency and immobilization yield of dextranase enzyme onto calcium alginate beads were investigated. Furthermore, the activities of immobilized enzymes prepared with and without US/HHP treatments and that prepared with ultrasonic irradiation (US) and high hydrostatic pressure (HHP), as a function of pH, temperature, recyclability and enzyme kinetic parameters, were compared with that for free enzyme. The maximum loading efficiency and the immobilization yield were observed when the immobilized dextranase was prepared with US (40 W at 25 kHz for 15 min) combined with HHP (400 MPa for 15 min), under which the loading efficiency and the immobilization yield increased by 88.92% and 80.86%, respectively, compared to immobilized enzymes prepared without US/HHP treatment. On the other hand, immobilized enzyme prepared with US/HHP treatment showed Vmax, KM, catalytic and specificity constants values higher than that for the immobilized enzyme prepared with HHP treatment, indicated that, this new US/HHP method improved the catalytic kinetics activity of immobilized dextranase at all the reaction conditions studied. Compared to immobilized enzyme prepared either with US or HHP, the immobilized enzymes prepared with US/HHP method exhibited a higher: pH optimum, optimal reaction temperature, thermal stability and recyclability, and lower activation energy, which, illustrating the effectiveness of the US/HHP method. These results indicated that, the combination of US and HHP treatments could be an effective method for improving the immobilization of enzymes in polymers. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. MO-FG-210-00: US Guided Systems for Brachytherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Ultrasound (US) is one of the most widely used imaging modalities in medical practice. Since US imaging offers real-time imaging capability, it has becomes an excellent option to provide image guidance for brachytherapy (IGBT). (1) The physics and the fundamental principles of US imaging are presented, and the typical steps required to commission an US system for IGBT is provided for illustration. (2) Application of US for prostate HDR brachytherapy, including partial prostate treatments using MR-ultrasound co-registration to enable a focused treatment on the disease within the prostate is also presented. Prostate HDR with US image guidance planning can benefitmore » from real time visualization of the needles, and fusion of the ultrasound images with T2 weighted MR allows the focusing of the treatment to the specific areas of disease within the prostate, so that the entire gland need not be treated. Finally, (3) ultrasound guidance for an eye plaque program is presented. US can be a key component of placement and QA for episcleral plaque brachytherapy for ocular cancer, and the UCLA eye plaque program with US for image guidance is presented to demonstrate the utility of US verification of plaque placement in improving the methods and QA in episcleral plaque brachytherapy. Learning Objectives: To understand the physics of an US system and the necessary aspects of commissioning US for image guided brachytherapy (IGBT). To understand real time planning of prostate HDR using ultrasound, and its application in partial prostate treatments using MR-ultrasound fusion to focus treatment on disease within the prostate. To understand the methods and QA in applying US for localizing the target and the implant during a episcleral plaque brachytherapy procedures.« less

  8. MO-FG-210-01: Commissioning An US System for Brachytherapy: An Overview of Physics, Instrumentation, and Techniques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chang, Z.

    Ultrasound (US) is one of the most widely used imaging modalities in medical practice. Since US imaging offers real-time imaging capability, it has becomes an excellent option to provide image guidance for brachytherapy (IGBT). (1) The physics and the fundamental principles of US imaging are presented, and the typical steps required to commission an US system for IGBT is provided for illustration. (2) Application of US for prostate HDR brachytherapy, including partial prostate treatments using MR-ultrasound co-registration to enable a focused treatment on the disease within the prostate is also presented. Prostate HDR with US image guidance planning can benefitmore » from real time visualization of the needles, and fusion of the ultrasound images with T2 weighted MR allows the focusing of the treatment to the specific areas of disease within the prostate, so that the entire gland need not be treated. Finally, (3) ultrasound guidance for an eye plaque program is presented. US can be a key component of placement and QA for episcleral plaque brachytherapy for ocular cancer, and the UCLA eye plaque program with US for image guidance is presented to demonstrate the utility of US verification of plaque placement in improving the methods and QA in episcleral plaque brachytherapy. Learning Objectives: To understand the physics of an US system and the necessary aspects of commissioning US for image guided brachytherapy (IGBT). To understand real time planning of prostate HDR using ultrasound, and its application in partial prostate treatments using MR-ultrasound fusion to focus treatment on disease within the prostate. To understand the methods and QA in applying US for localizing the target and the implant during a episcleral plaque brachytherapy procedures.« less

  9. Emergency Department Patient Perceptions of Transvaginal Ultrasound for Complications of First-Trimester Pregnancy.

    PubMed

    Panebianco, Nova; Shofer, Frances; O'Conor, Katie; Wihbey, Tristan; Mulugeta, Lakeisha; Baston, Cameron M; Suzuki, Evan; Alghamdi, Adel; Dean, Anthony

    2018-01-30

    Emergency department (ED) transvaginal ultrasound (US) is underused in clinical practice. This study assessed pregnant women's perceptions of ED transvaginal US in terms of pain, embarrassment, anxiety, and willingness to receive the procedure. Secondary variables include physicians' perceptions of patients' experiences. Women undergoing US examinations for complications of first-trimester pregnancy were prospectively surveyed before any US and after ED and/or radiology transvaginal US. Patients' and physicians' assessments of pain, embarrassment, and anxiety were measured with visual analog scales (0-100). A total of 398 women were enrolled. In the pre-US survey, the median anxiety score was 14 (interquartile range, 3-51), and 96% of patients were willing to have an ED transvaginal US if necessary. Of those who had ED transvaginal US, 96% would agree to have another examination. Patients reported minimal pain/embarrassment, and there was no difference if performed in the ED versus radiology (median pain, 11.5 versus 13; P = .433; median embarrassment, 7 versus 4; P = .345). Of the 48 who had both ED and radiology transvaginal US, 85% thought the ED transvaginal US was worthwhile. Physicians accurately assessed patient's embarrassment and pain (mean differences, 3.5 and -1.9, respectively; P > .25 for both); however, they overestimated them relative to the pelvic examination (mean difference for embarrassment, 12.8; P < .0001; pain, 8.0; P = .01). Pregnant ED patients report low levels of anxiety, pain, and embarrassment, and after ED transvaginal US, 96% would agree to have the examination again. There is no difference in pain/embarrassment between ED and radiology transvaginal US. Emergency department physicians accurately assessed patients' pain and embarrassment with ED transvaginal US but overestimated them compared to the pelvic examination. © 2018 by the American Institute of Ultrasound in Medicine.

  10. DASH Eating Plan

    MedlinePlus

    ... Card Other Resources ChooseMyPlate.gov (U.S. Department of Agriculture, U.S. Department of Health and Human Services) DASH ( ... Dietary Guidelines for Americans, 2010 (U.S. Department of Agriculture, U.S. Department of Health and Human Services) High ...

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yokosawa, A.

    The author described the polarized-proton and polarized-antiproton beams up to 200 GeV/c at Fermilab. The beam line, called MP, consists of the 400-m long primary and 350-m long secondary beam line followed by 60-m long experimental hall. We discuss the characteristics of the polarized beams. The Fermilab polarization projects are designated at E-581/704 initiated and carried out by an international collaboration, Argonne (US), Fermilab (US), Kyoto-Kyushu-Hiroshima-KEK (Japan), LAPP (France), Northwestern University (US), Los Alamos Laboratory (US), Rice (US), Saclay (France), Serpukhov (USSR), INFN Trieste (Italy), and University of Texas (US).

  12. U.S. Trade and Investment Relationship with Sub-Saharan Africa: The African Growth and Opportunity Act

    DTIC Science & Technology

    2009-07-24

    Africa Domestic Exports, FAS value; Imports for Consumption , Customs Value; Actual U.S. dollars Trade Flow 2007 2008 Jan. – May 2008 Jan. –May 2009 U.S...first part of 2009. However, decreases in U.S. and global consumption are likely to continue to have a negative effect on most exports from the region.39...Table 3. Leading U.S. Imports from Sub-Saharan Africa U.S. Imports for Consumption , Customs Value, Actual U.S. dollars HTS Description 2007 2008

  13. Single-Use Devices in Argentina: Cost Comparison Analysis of a "Re-Use" versus a "Single-Use" Policy for Trocars, Endocutters, Linear Cutters, and Harmonic Scalpels.

    PubMed

    Garay, Osvaldo Ulises; Elorrio, Ezequiel Garcia; Rodríguez, Viviana; Spira, Cintia; Augustovski, Federico; Pichon-Riviere, Andrés

    2017-12-01

    Re-use of medical devices labeled and marketed for single use only is a current practice around the world. To estimate the average difference per surgery in device-related costs (DRCs) when performed with single-use devices under a single-use policy (SUP) instead of a re-use policy (RP) from the perspective of the private health sector of Argentina. An analytical model was developed in Microsoft Excel and populated with data from a literature review, a Delphi-like panel, and local cost estimations. Four single-use devices were selected for analysis: plastic trocars, endocutters, linear cutters, and harmonic scalpels. DRCs were expressed in 2012 US dollars and divided into four cost categories: devices, adverse events, device failure, and surgical time extension. Outputs were expressed as DRCs per surgery under a SUP, under a RP, the difference between them expressed in US dollars (Diff_$), and the difference between them expressed as a percentage of surgery costs (Diff_%S). Deterministic and probabilistic sensitivity analyses were performed to analyze the impact of uncertainty on results. Expected DRCs per surgery were as follows: for trocars: SUP, US $424.6; RP, US $244.2; Diff_$, US $-180.4; and Diff_%S, -3.8%; for endocutters: SUP, US $1667.4; RP, US $1102.3; Diff_$, US $-565.1; and Diff_%S, -11.1%; for linear cutters: SUP, US $1228.1; RP, US $1045.9; Diff_$, US $-182.2; and Diff_%S, -3.4%; and for harmonic scalpels: SUP, US $1040.9; RP, US $292.4; Diff_$, US $-748.5; and Diff_%S, -14.8%. Sensitivity analyses showed results to be robust. RP was shown to be less costly in all devices and scenarios considered. Nevertheless, the real frequency of adverse events and their cost implications are still uncertain. More research is needed to assess the effectiveness and safety of these off-label policies. Copyright © 2017. Published by Elsevier Inc.

  14. Correlations between the Various Methods of Estimating Prostate Volume: Transabdominal, Transrectal, and Three-Dimensional US

    PubMed Central

    Kim, Seung Hyup

    2008-01-01

    Objective To evaluate the correlations between prostate volumes estimated by transabdominal, transrectal, and three-dimensional US and the factors affecting the differences. Materials and Methods The prostate volumes of 94 consecutive patients were measured by both transabdominal and transrectal US. Next, the prostate volumes of 58 other patients was measured by both transrectal and three-dimensional US. We evaluated the degree of correlation and mean difference in each comparison. We also analyzed possible factors affecting the differences, such as the experiences of examiners in transrectal US, bladder volume, and prostate volume. Results In the comparison of transabdominal and transrectal US methods, the mean difference was 8.4 ± 10.5 mL and correlation coefficient (r) was 0.775 (p < 0.01). The experienced examiner for the transrectal US method had the highest correlation (r = 0.967) and the significantly smallest difference (5.4 ± 3.9 mL) compared to the other examiners (the beginner and the trained; p < 0.05). Prostate volume measured by transrectal US showed a weak correlation with the difference (r = 0.360, p < 0.05). Bladder volume did not show significant correlation with the difference (r = -0.043, p > 0.05). The comparison between the transrectal and three-dimensional US methods revealed a mean difference of 3.7 ± 3.4 mL and the correlation coefficient was 0.924 for the experienced examiner. Furthermore, no significant difference existed between examiners (p > 0.05). Prostate volume measured by transrectal US showed a positive correlation with the difference for the beginner only (r = 0.405, p < 0.05). Conclusion In the prostate volume estimation by US, experience in transrectal US is important in the correlation with transabdominal US, but not with three-dimensional US. Also, less experienced examiners' assessment of the prostate volume can be affected by prostate volume itself. PMID:18385560

  15. A risk-adapted approach using US features and FNA results in the management of thyroid incidentalomas identified by 18F-FDG PET.

    PubMed

    Choi, J S; Choi, Y- J; Kim, E K; Yoon, J H; Youk, J H; Han, K H; Moon, H J; Kang, W J; Kwak, J Y

    2014-02-01

    To assess the risk of malignancy of thyroid incidentalomas found on 18F-FDG PET/CT by US features and cytologic results, and to evaluate the clinical usage of a combination of US features and cytology for post-FNA management of thyroid incidentalomas on 18F-FDG PET/CT. From September 2006 to December 2008, 132 patients with 134 thyroid incidentalomas detected on 18F-FDG PET/CT who had undergone US and US-FNA were included in this study. We evaluated the malignancy rate of thyroid incidentalomas in different subgroups subdivided by US features and US-FNA cytology results. Several variables were compared between the benign and malignant group. The risk of malignancy was 58.2 % (78/132) in thyroid incidentalomas on 18F-FDG PET/CT. Age, gender, and tumor size were not significantly different between the malignant and benign group.  Malignancy rate of thyroid incidentalomas was significantly higher in the suspicious malignant (88.9 %) than in the probably benign group (11.3 %) on US (p < 0.001). Malignancy rates were high in thyroid nodules with "malignancy", "suspicious for malignancy", or "follicular neoplasm" on cytologic results, regardless of US features. However, malignancy rates of thyroid incidentalomas with "unsatisfactory" or "benign" results on cytology were higher in the suspicious malignant (75 %, 12.5 %, respectively) than in the probably benign (0 %) group on US.  This study demonstrated that the risk of malignancy was high in thyroid incidentalomas on 18F-FDG PET/CT even without suspicious US features. However, there was no malignancy in nodules with no suspicious US features and benign cytology. Based on these results, we concluded that US may not replace FNA in the diagnosis of PET incidentalomas, and that a follow-up may be considered of thyroid incidentalomas with benign cytology and no suspicious US features. © Georg Thieme Verlag KG Stuttgart · New York.

  16. Inhibition of prostate cancer growth using doxorubicin assisted by ultrasound-targeted nanobubble destruction

    PubMed Central

    Fan, Xiaozhou; Wang, Luofu; Guo, Yanli; Xiong, Xingyu; Zhu, Lianhua; Fang, Kejing

    2016-01-01

    Ultrasound (US)-targeted microbubble destruction has been widely used as an effective drug-delivery system. However, nanobubbles (NBs) have better stability and stronger penetration than microbubbles, and drug delivery assisted by US-targeted NB destruction (UTND) still needs to be investigated. Our aim was to investigate the effect of doxorubicin (DOX) on the inhibition of prostate cancer growth under UTND. Contrast-enhanced US imaging of transplanted PC3 prostate cancer in mice showed that under a combination of 1 W/cm2 US power and a 100 Hz intermittent pulse with a “5 seconds on, 5 seconds off” mode, NBs with an average size of (485.7±33) nm were effectively destroyed within 15 minutes in the tumor location. PC3 cells and 20 tumor-bearing mice were divided into four groups: a DOX group, a DOX + NB group, a DOX + US group, and a DOX + NB + US group. The cell growth-inhibition rate and DOX concentration of xenografts in the DOX + NB + US group were highest. Based on another control group and these four groups, another 25 tumor-bearing mice were used to observe the treatment effect of nine DOX injections under UTND. The xenografts in the DOX + NB + US group decreased more obviously and had more cellular apoptosis than other groups. Finally, electron microscopy was used to estimate the cavitation effect of NBs under US irradiation in the control group, NB group, US group, and NB + US group. The results of scanning electron microscopy showed that PC3 cells in the DOX + NB + US group had more holes and significantly increased cell-surface folds. Meanwhile, transmission electric microscopy confirmed that more lanthanum nitrate particles entered the parenchymal cells in xenografts in the NB + US group compared with the other groups. This study suggested that UTND technology could be an effective method to promote drugs to function in US-irradiated sites, and the underlying mechanism may be associated with a cavitation effect. PMID:27536100

  17. Investment, population growth and GNP as determinants of US immigration.

    PubMed

    Kritz, M M

    1998-09-01

    Northern countries typically attract migrants from poorer countries because of the formers' high wage rates and demand for labor. In particular, the US receives large numbers of legal migrants from almost every country and region of the world. This paper explores the determinants of permanent emigration to the US during 1989-93 using data drawn from the US Immigration and Naturalization Service (INS) Annual Tapes for the period. The analysis is restricted to only legal migration from 150 countries, and specifically investigates whether emigration to the US during 1989-93 can be accounted for by demographic and economic conditions in sending countries, or by levels of US investment in sending countries. No support is found for claims that rapid population growth and US investment fuel US immigration; emigration is comparatively far lower from countries experiencing rapid population growth and not significantly correlated with US investment, while the US typically invests the most in the more developed countries which send relatively few migrants to the US. Geographic proximity is the most important correlate of migration, followed by the population size of sending countries, which is negatively related to emigration. Some evidence was found that emigration will decrease as countries develop. Who a country decides to admit and how many people are admitted depend mainly upon public policy and very little upon the economic and demographic conditions of sending countries.

  18. Impact of medical travel on imports and exports of medical services.

    PubMed

    Johnson, Tricia J; Garman, Andrew N

    2010-12-01

    Medical travel is travel outside of an individual's home region or country in pursuit of medical care that is more accessible, of higher quality and/or of lower cost. This paper estimates the inflows of foreign residents seeking medical care in the U.S. and outflows of U.S. residents seeking care abroad. Using data from the U.S. Bureau of Economic Analysis, U.S. International Trade Administration and a survey of domestic health care providers, we estimate the lower and upper bounds for the number of medical travelers into and out of the U.S. and the value of these services. We estimate that between 43,000 and 103,000 foreigners came into the U.S. for medical care, and between 50,000 and 121,000 U.S. residents traveled abroad for care in 2007. Despite a net loss in the number of medical travelers flowing out of the U.S. for care, the trade surplus for medical travel could be as high as $1 billion. While a slight net outflow of patients leaving the U.S. for medical care may exist, the resulting impact on exports is still positive for the U.S., due to a higher average spending per patient coming to the U.S. New mechanisms are needed to track the balance of mobility and trade for medical care on a regular basis. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  19. First Preserve America Community and Stewards Designations Under Obama

    Science.gov Websites

    Council on Historic Preservation; the U.S. Departments of Defense, Interior, Agriculture, Commerce . Department of the Interior seal U.S. Department of Commerce seal U.S. Department of Agriculture logo U.S

  20. Contact Us | NREL

    Science.gov Websites

    Contact Us Contact Us Find a contact to help answer your question, resolve a website issue, or job or internship, or want to report an issue with the application process, contact us about careers

  1. U.S. Emissions Inventory 1997

    EPA Pesticide Factsheets

    View the 1997 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 1995.

  2. National Council on Aging

    MedlinePlus

    ... Sign Up for News Follow Us in Your Network Like Us on Facebook Follow Us on Twitter Join Us on LinkedIn Sign Up for News Improving the health and economic security of 10 million older adults by 2020 Economic ...

  3. Ultrasound Produces Extensive Brain Activation via a Cochlear Pathway.

    PubMed

    Guo, Hongsun; Hamilton, Mark; Offutt, Sarah J; Gloeckner, Cory D; Li, Tianqi; Kim, Yohan; Legon, Wynn; Alford, Jamu K; Lim, Hubert H

    2018-06-06

    Ultrasound (US) can noninvasively activate intact brain circuits, making it a promising neuromodulation technique. However, little is known about the underlying mechanism. Here, we apply transcranial US and perform brain mapping studies in guinea pigs using extracellular electrophysiology. We find that US elicits extensive activation across cortical and subcortical brain regions. However, transection of the auditory nerves or removal of cochlear fluids eliminates the US-induced activity, revealing an indirect auditory mechanism for US neural activation. Our findings indicate that US activates the ascending auditory system through a cochlear pathway, which can activate other non-auditory regions through cross-modal projections. This cochlear pathway mechanism challenges the idea that US can directly activate neurons in the intact brain, suggesting that future US stimulation studies will need to control for this effect to reach reliable conclusions. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. Perceptions of Clinical Education Preparedness at a Large Urban US University: Is There a Difference between US-Born and Non-US Born Students?

    ERIC Educational Resources Information Center

    Cohen, Timmerie; Justice, M. Ferell; Dempsey, Melanie C.

    2014-01-01

    This research compared three clinical preparedness domains, communication ability, social comfort, and clinical confidence, between US-born and non-US born radiation sciences students. The aim of the study was to determine if there were perceived differences in clinical preparedness between them. Student's place of birth was found to be an…

  5. 77 FR 40088 - Rollins College; T.A. Loving Co.; US Ecology Idaho, Inc.; and West Pharmaceutical Services, Inc...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ...] Rollins College; T.A. Loving Co.; US Ecology Idaho, Inc.; and West Pharmaceutical Services, Inc... 11481 1910.37(i). T.A. Loving Co V-74-43 04/13/1976 41 FR 15483 1918.66(f)(1)(i). US Ecology Idaho, Inc.... US Ecology Idaho, Inc. The Agency granted Envirosafe Services, Inc. (now US Ecology Idaho, Inc.), a...

  6. Eastern U.S. Infrared, Enhancement 4 - NOAA GOES Geostationary Satellite

    Science.gov Websites

    Enhancement 4 Eastern U.S. Infrared Enhancements IR Enhancement 1 Eastern U.S. Infrared Enhancement 1 IR Enhancement 2 Eastern U.S. Infrared Enhancement 2 IR Enhancement 3 Eastern U.S. Infrared Enhancement 3 IR large amount of water vapor. » Enhancement types In an infrared (IR) image cold clouds are high clouds

  7. Directory of Services: Federal Agencies and Non-Federal Organizations Providing Services to Migrant and Seasonal Farmworkers and Their Families.

    ERIC Educational Resources Information Center

    Office of Elementary and Secondary Education (ED), Washington, DC. Migrant Education Programs.

    This directory promotes better coordination among agencies and organizations that serve migrant and seasonal farmworkers (MSFWs) and their families. The U.S. Department of Agriculture, the U.S. Department of Education, the U.S. Environmental Protection Agency, the U.S. Department of Health and Human Services, the U.S. Department of Justice, and…

  8. Preparing for Post-Embargo Cuba: Effects on Businesses and Consumers.

    ERIC Educational Resources Information Center

    Ray, Nina M.; And Others

    1995-01-01

    Discusses a brief history of U.S. trade with Cuba, the current status of Cuba's role in world trade, and the effects the U.S. embargo has on American businesses and U.S. and Cuban citizens. The article presents suggestions on how U.S. businesses can prepare for an open Cuba and argues for the lifting of the U.S. embargo against Cuba. (84…

  9. 17 CFR Appendix A to Part 151 - Spot-Month Position Limits

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Referencedcontract spot- month limit Agricultural Referenced Contracts ICE Futures U.S. Cocoa 1,000 ICE Futures U.S. Coffee C 500 Chicago Board of Trade Corn 600 ICE Futures U.S. Cotton No. 2 300 ICE Futures U.S. FCOJ-A... of Trade Soybean Meal 720 Chicago Board of Trade Soybean Oil 540 ICE Futures U.S. Sugar No. 11 5,000...

  10. 17 CFR Appendix A to Part 151 - Spot-Month Position Limits

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Referencedcontract spot- month limit Agricultural Referenced Contracts ICE Futures U.S. Cocoa 1,000 ICE Futures U.S. Coffee C 500 Chicago Board of Trade Corn 600 ICE Futures U.S. Cotton No. 2 300 ICE Futures U.S. FCOJ-A... of Trade Soybean Meal 720 Chicago Board of Trade Soybean Oil 540 ICE Futures U.S. Sugar No. 11 5,000...

  11. A Case Study on the Development and Implementation of Cyber Capabilities in the United States

    ERIC Educational Resources Information Center

    Walton, Marquetta

    2016-01-01

    The effectiveness of U.S. cyber-capabilities can have a serious effect on the cyber-security stance of the US and significantly impact how well U.S. critical infrastructures are protected. The problem is that the state of the U.S. cyber-security could be negatively impacted by the dependency that the US displays in its use of defensive…

  12. Profile of GMAT® Testing: North American Report. Testing Years 2010 through 2014. GMAC® Data-to-Go Series

    ERIC Educational Resources Information Center

    Chisholm, Alex

    2014-01-01

    This Data-to-Go brief summarizes five year GMAT testing trends for US and Canadian residents, and race/ethnicity breakdowns for US citizens. It includes: (1) GMAT exams taken by US region, US state of residence, and race/ethnicity of examinees (US citizens only), (2) GMAT exams taken by Canadian residents, by Canadian province, (3) GMAT exams…

  13. Cost-Effectiveness of Early Versus Standard Antiretroviral Therapy in HIV-Infected Adults in Haiti

    PubMed Central

    Koenig, Serena P.; Bang, Heejung; Severe, Patrice; Jean Juste, Marc Antoine; Ambroise, Alex; Edwards, Alison; Hippolyte, Jessica; Fitzgerald, Daniel W.; McGreevy, Jolion; Riviere, Cynthia; Marcelin, Serge; Secours, Rode; Johnson, Warren D.; Pape, Jean W.; Schackman, Bruce R.

    2011-01-01

    Background In a randomized clinical trial of early versus standard antiretroviral therapy (ART) in HIV-infected adults with a CD4 cell count between 200 and 350 cells/mm3 in Haiti, early ART decreased mortality by 75%. We assessed the cost-effectiveness of early versus standard ART in this trial. Methods and Findings Trial data included use of ART and other medications, laboratory tests, outpatient visits, radiographic studies, procedures, and hospital services. Medication, laboratory, radiograph, labor, and overhead costs were from the study clinic, and hospital and procedure costs were from local providers. We evaluated cost per year of life saved (YLS), including patient and caregiver costs, with a median of 21 months and maximum of 36 months of follow-up, and with costs and life expectancy discounted at 3% per annum. Between 2005 and 2008, 816 participants were enrolled and followed for a median of 21 months. Mean total costs per patient during the trial were US$1,381 for early ART and US$1,033 for standard ART. After excluding research-related laboratory tests without clinical benefit, costs were US$1,158 (early ART) and US$979 (standard ART). Early ART patients had higher mean costs for ART (US$398 versus US$81) but lower costs for non-ART medications, CD4 cell counts, clinically indicated tests, and radiographs (US$275 versus US$384). The cost-effectiveness ratio after a maximum of 3 years for early versus standard ART was US$3,975/YLS (95% CI US$2,129/YLS–US$9,979/YLS) including research-related tests, and US$2,050/YLS excluding research-related tests (95% CI US$722/YLS–US$5,537/YLS). Conclusions Initiating ART in HIV-infected adults with a CD4 cell count between 200 and 350 cells/mm3 in Haiti, consistent with World Health Organization advice, was cost-effective (US$/YLS <3 times gross domestic product per capita) after a maximum of 3 years, after excluding research-related laboratory tests. Trial registration ClinicalTrials.gov NCT00120510 Please see later in the article for the Editors' Summary PMID:21949643

  14. Variation in Patient Profiles and Outcomes in US and Non-US Subgroups of the Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition (CHAMPION) PHOENIX Trial

    PubMed Central

    Vaduganathan, Muthiah; Harrington, Robert A.; Stone, Gregg W.; Steg, Ph. Gabriel; Gibson, C. Michael; Hamm, Christian W.; Price, Matthew J.; Prats, Jayne; Deliargyris, Efthymios N.; Mahaffey, Kenneth W.; White, Harvey D.

    2016-01-01

    Background— The Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition (CHAMPION) PHOENIX trial demonstrated superiority of cangrelor in reducing ischemic events at 48 hours in patients undergoing percutaneous coronary intervention compared with clopidogrel. Methods and Results— We analyzed all patients included in the modified intention-to-treat analysis in US (n=4097; 37.4%) and non-US subgroups (n=6845; 62.6%). The US cohort was older, had a higher burden of cardiovascular risk factors, and had more frequently undergone prior cardiovascular procedures. US patients more frequently underwent percutaneous coronary intervention for stable angina (77.9% versus 46.2%). Almost all US patients (99.1%) received clopidogrel loading doses of 600 mg, whereas 40.5% of non-US patients received 300 mg. Bivalirudin was more frequently used in US patients (56.7% versus 2.9%). At 48 hours, rates of the primary composite end point were comparable in the US and non-US cohorts (5.5% versus 5.2%; P=0.53). Cangrelor reduced rates of the primary composite end point compared with clopidogrel in US (4.5% versus 6.4%; odds ratio 0.70 [95% confidence interval 0.53–0.92]) and in non-US patients (4.8% versus 5.6%; odds ratio 0.85 [95% confidence interval 0.69–1.05]; interaction P=0.26). Similarly, rates of the key secondary end point, stent thrombosis, were reduced by cangrelor in both regions. Rates of Global Use of Strategies to Open Occluded Arteries (GUSTO)–defined severe bleeding were low and not significantly increased by cangrelor in either region. Conclusions— Despite broad differences in clinical profiles and indications for percutaneous coronary intervention by region in a large global cardiovascular clinical trial, cangrelor consistently reduced rates of ischemic end points compared with clopidogrel without an excess in severe bleeding in both the US and non-US subgroups. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01156571. PMID:27313282

  15. Role of specimen US for predicting resection margin status in breast conserving therapy

    PubMed Central

    MOSCHETTA, M.; TELEGRAFO, M.; INTRONA, T.; COI, L.; RELLA, L.; RANIERI, V.; CIRILLI, A.; IANORA, A.A. STABILE; ANGELELLI, G.

    2015-01-01

    Aim To assess the diagnostic accuracy of specimen ultrasound (US) for predicting resection margin status in women undergoing breast conserving therapy for US-detected cancer, having the histological findings as the reference standard. Patients and methods A total of 132 consecutive patients (age range, 34–87 years; mean, 51 years) underwent breast-conserving surgery for US-detected invasive breast cancer. All surgical specimens underwent US examination. The presence of lesion within the specimen and its distance from the specimen margins were assessed considering a threshold distance between the lesion and specimen margins of 10 mm. US findings were then compared with the pathological ones and specimen US. Sensitivity, specificity, diagnostic accuracy, positive (PPV) and negative predictive values (NPV) for predicting histological margin status were evaluated, having the histological findings as the reference standard. Results The histological examination detected invasive ductal carcinoma in 96/132 (73%) cases, invasive lobular carcinoma in 32/132 (24%), mucinous carcinoma in 4/132 (3%). The pathological margin analysis revealed 96/132 (73%) negative margins and 36 (27%) close/positive margins. US examination detected all 132 breast lesions within the surgical specimens. 110 (83%) negative margins and 22 (17%) positive margins were found on US. Sensitivity, specificity, diagnostic accuracy, PPV and NPV of 44%, 94%, 80%, 73% and 82%, respectively, were found for specimen US. Conclusions Specimen US represents a time and cost saving imaging tool for evaluating the presence of US detected-breast lesion within surgical specimen and for predicting the histological margin status. PMID:26712255

  16. Use of a decision-analytic model to support the use of a new oral US contrast agent in patients with abdominal pain.

    PubMed

    Bree, R L; Arnold, R J; Pettit, K G; Kaniecki, D J; O'haeri, C; LaFrance, N D; Toaff, A L

    2001-03-01

    The authors performed this study to compare the cost and diagnostic abilities of ultrasound (US) performed with and without the use of an oral contrast material recently approved by the U.S. Food and Drug Administration. An interactive decision-analytic model was constructed to compare US performed with and without contrast material (SonoRx; Bracco Diagnostics) for the evaluation of patients with abdominal pain who were suspected of having pancreatic disease. The model considered all resources that might be used to evaluate a patient suspected of having pancreatic disease (eg, US, computed tomography [CT], endoscopic retrograde cholangiopancreatography, fine-needle aspiration biopsy, and open biopsy). The literature and an expert panel were the clinical data sources. Cost estimates were based on Medicare and non-Medicare reimbursements. The primary cost-effectiveness measure was the cost to achieve a diagnosis. SonoRx-enhanced US was less expensive than unenhanced US ($714 vs $808, respectively, with Medicare costs; $1,612 vs $1,878, respectively, with non-Medicare costs) and as effective (0.785 vs 0.782, respectively). SonoRx-enhanced US was more cost-effective than unenhanced US ($909 vs $1,034, respectively, with Medicare costs; $2,052 vs $2,401, respectively, with non-Medicare costs). This relationship was maintained throughout extensive sensitivity analyses. SonoRx-enhanced US is more cost-effective than unenhanced US, primarily because it avoids the need for CT. CT may be avoided owing to the higher probability of obtaining optimal US scans with oral contrast material.

  17. NREL: U.S. Life Cycle Inventory Database - Publications

    Science.gov Websites

    Publications Planning Documents U.S. Life Cycle Inventory Database Roadmap, February 2009 U.S. Life Cycle Inventory User Survey, February 2009 U.S. LCI Database Factsheet, March 2005 User's Guide for Life

  18. Food Safety for People with HIV/AIDS

    MedlinePlus

    ... been diagnosed with HIV/AIDS U.S. Department of Agriculture Food Safety and Inspection Service U.S. Department of ... for you. That’s why the U.S. Department of Agriculture’s Food Safety and Inspection Service and the U.S. ...

  19. Operating and Support Costing Guide: Army Weapon Systems

    DTIC Science & Technology

    1974-12-23

    First US Army 1 Commandant, US Army Logistics Management Center (Director Administration and Services) 2 Commander, US Army Management Systems Support...Army Logistics Management Center (Director, Administration and Services) Commander, US Army Management Systems Support Agency (DACS-AME) Commander

  20. The economic costs of malaria in children in three sub-Saharan countries: Ghana, Tanzania and Kenya

    PubMed Central

    2013-01-01

    Background Malaria causes significant mortality and morbidity in sub-Saharan Africa (SSA), especially among children less than five years of age (U5 children). Although the economic burden of malaria in this region has been assessed previously, the extent and variation of this burden remains unclear. This study aimed to estimate the economic costs of malaria in U5 children in three countries (Ghana, Tanzania and Kenya). Methods Health system and household costs previously estimated were integrated with costs associated with co-morbidities, complications and productivity losses due to death. Several models were developed to estimate the expected treatment cost per episode per child, across different age groups, by level of severity and with or without controlling for treatment-seeking behaviour. Total annual costs (2009) were calculated by multiplying the treatment cost per episode according to severity by the number of episodes. Annual health system prevention costs were added to this estimate. Results Household and health system costs per malaria episode ranged from approximately US$ 5 for non-complicated malaria in Tanzania to US$ 288 for cerebral malaria with neurological sequelae in Kenya. On average, up to 55% of these costs in Ghana and Tanzania and 70% in Kenya were assumed by the household, and of these costs 46% in Ghana and 85% in Tanzania and Kenya were indirect costs. Expected values of potential future earnings (in thousands) lost due to premature death of children aged 0–1 and 1–4 years were US$ 11.8 and US$ 13.8 in Ghana, US$ 6.9 and US$ 8.1 in Tanzania, and US$ 7.6 and US$ 8.9 in Kenya, respectively. The expected treatment costs per episode per child ranged from a minimum of US$ 1.29 for children aged 2–11 months in Tanzania to a maximum of US$ 22.9 for children aged 0–24 months in Kenya. The total annual costs (in millions) were estimated at US$ 37.8, US$ 131.9 and US$ 109.0 nationwide in Ghana, Tanzania and Kenya and included average treatment costs per case of US$ 11.99, US$ 6.79 and US$ 20.54, respectively. Conclusion This study provides important insight into the economic burden of malaria in SSA that may assist policy makers when designing future malaria control interventions. PMID:24004482

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