Kok, Maryse C; Kea, Aschenaki Z; Datiko, Daniel G; Broerse, Jacqueline E W; Dieleman, Marjolein; Taegtmeyer, Miriam; Tulloch, Olivia
2015-09-30
Health extension workers (HEWs) in Ethiopia have a unique position, connecting communities to the health sector. This intermediary position requires strong interpersonal relationships with actors in both the community and health sector, in order to enhance HEW performance. This study aimed to understand how relationships between HEWs, the community and health sector were shaped, in order to inform policy on optimizing HEW performance in providing maternal health services. We conducted a qualitative study in six districts in the Sidama zone, which included focus group discussions (FGDs) with HEWs, women and men from the community and semi-structured interviews with HEWs; key informants working in programme management, health service delivery and supervision of HEWs; mothers; and traditional birth attendants. Respondents were asked about facilitators and barriers regarding HEWs' relationships with the community and health sector. Interviews and FGDs were recorded, transcribed, translated, coded and thematically analysed. HEWs were selected by their communities, which enhanced trust and engagement between them. Relationships were facilitated by programme design elements related to support, referral, supervision, training, monitoring and accountability. Trust, communication and dialogue and expectations influenced the strength of relationships. From the community side, the health development army supported HEWs in liaising with community members. From the health sector side, top-down supervision and inadequate training possibilities hampered relationships and demotivated HEWs. Health professionals, administrators, HEWs and communities occasionally met to monitor HEW and programme performance. Expectations from the community and health sector regarding HEWs' tasks sometimes differed, negatively affecting motivation and satisfaction of HEWs. HEWs' relationships with the community and health sector can be constrained as a result of inadequate support systems, lack of trust, communication and dialogue and differing expectations. Clearly defined roles at all levels and standardized support, monitoring and accountability, referral, supervision and training, which are executed regularly with clear communication lines, could improve dialogue and trust between HEWs and actors from the community and health sector. This is important to increase HEW performance and maximize the value of HEWs' unique position.
Lowe, Dianne; Ebi, Kristie L; Forsberg, Bertil
2011-12-01
With climate change, there has been an increase in the frequency, intensity and duration of heatwave events. In response to the devastating mortality and morbidity of recent heatwave events, many countries have introduced heatwave early warning systems (HEWS). HEWS are designed to reduce the avoidable human health consequences of heatwaves through timely notification of prevention measures to vulnerable populations. To identify the key characteristics of HEWS in European countries to help inform modification of current, and development of, new systems and plans. We searched the internet to identify HEWS policy or government documents for 33 European countries and requested information from relevant organizations. We translated the HEWS documents and extracted details on the trigger indicators, thresholds for action, notification strategies, message intermediaries, communication and dissemination strategies, prevention strategies recommended and specified target audiences. Twelve European countries have HEWS. Although there are many similarities among the HEWS, there also are differences in key characteristics that could inform improvements in heatwave early warning plans.
Lowe, Dianne; Ebi, Kristie L.; Forsberg, Bertil
2011-01-01
Introduction: With climate change, there has been an increase in the frequency, intensity and duration of heatwave events. In response to the devastating mortality and morbidity of recent heatwave events, many countries have introduced heatwave early warning systems (HEWS). HEWS are designed to reduce the avoidable human health consequences of heatwaves through timely notification of prevention measures to vulnerable populations. Objective: To identify the key characteristics of HEWS in European countries to help inform modification of current, and development of, new systems and plans. Methods: We searched the internet to identify HEWS policy or government documents for 33 European countries and requested information from relevant organizations. We translated the HEWS documents and extracted details on the trigger indicators, thresholds for action, notification strategies, message intermediaries, communication and dissemination strategies, prevention strategies recommended and specified target audiences. Findings and Conclusions: Twelve European countries have HEWS. Although there are many similarities among the HEWS, there also are differences in key characteristics that could inform improvements in heatwave early warning plans. PMID:22408593
Ordinary Americans: U.S. History through the Eyes of Everyday People [and] Teacher's Guide.
ERIC Educational Resources Information Center
Monk, Linda R., Ed.
"Ordinary Americans" covers 500 years of U.S. history, from 1492 to 1992, in almost 200 readings, plus scores of archival photographs. The book relates the traditional events of U.S. history, but as an ordinary person lived it. Thus, the story of the Boston Tea Party is told not by Samuel Adams, but by George Hewes, a cobbler. The story of the…
ERIC Educational Resources Information Center
Truckenmiller, James L.
The former HEW (Health, Education, and Welfare) National Strategy for Youth Development Model proposed a community-based program to promote positive youth development and to prevent delinquency through a sequence of youth needs assessments, needs-targeted programs, and program impact evaluation. HEW Community Program Impact Scales data obtained…
Shaw, Bryan; Amouzou, Agbessi; Miller, Nathan P; Tafesse, Mengistu; Bryce, Jennifer; Surkan, Pamela J
2016-01-01
Background: In 2010, Ethiopia began scaling up the integrated community case management (iCCM) of childhood illness strategy throughout the country allowing health extension workers (HEWs) to treat children in rural health posts. After 2 years of iCCM scale up, utilization of HEWs remains low. Little is known about factors related to the use of health services in this setting. This research aimed to elicit perceptions and experiences of caregivers to better understand reasons for low utilization of iCCM services. Methods: A rapid ethnographic assessment was conducted in eight rural health post catchment areas in two zones: Jimma and West Hararghe. In total, 16 focus group discussions and 78 in-depth interviews were completed with mothers, fathers, HEWs and community health volunteers. Results: In spite of the HEW being a core component of iCCM, we found that the lack of availability of HEWs at the health post was one of the most common barriers to the utilization of iCCM services mentioned by caregivers. Financial and geographic challenges continue to influence caregiver decisions despite extension of free child health services in communities. Acceptability of HEWs was often low due to a perceived lack of sensitivity of HEWs and concerns about medicines given at the health post. Social networks acted both to facilitate and hinder use of HEWs. Many mothers stated a preference for using the health post, but some were unable to do so due to objections or alternative care-seeking preferences of gatekeepers, often mothers-in-law and husbands. Conclusion: Caregivers in Ethiopia face many challenges in using HEWs at the health post, potentially resulting in low demand for iCCM services. Efforts to minimize barriers to care seeking and to improve demand should be incorporated into the iCCM strategy in order to achieve reductions in child mortality and promote equity in access and child health outcomes. PMID:26608585
Canavan, Maureen E.; Linnander, Erika; Ahmed, Shirin; Mohammed, Halima; Bradley, Elizabeth H.
2018-01-01
Background: Over the last decade, Ethiopia has made impressive national improvements in health outcomes, including reductions in maternal, neonatal, infant, and child mortality attributed in large part to their Health Extension Program (HEP). As this program continues to evolve and improve, understanding the unit cost of health extension worker (HEW) services is fundamental to planning for future growth and ensuring adequate financial support to deliver effective primary care throughout the country. Methods: We sought to examine and report the data needed to generate a HEW fee schedule that would allow for full cost recovery for HEW services. Using HEW activity data and estimates from national studies and local systems we were able to estimate salary costs and the average time spent by an HEW per patient/community encounter for each type of services associated with specific users. Using this information, we created separate fee schedules for activities in urban and rural settings with two estimates of non-salary multipliers to calculate the total cost for HEW services. Results: In the urban areas, the HEW fees for full cost recovery of the provision of services (including salary, supplies, and overhead costs) ranged from 55.1 birr to 209.1 birr per encounter. The rural HEW fees ranged from 19.6 birr to 219.4 birr. Conclusion: Efforts to support health system strengthening in low-income settings have often neglected to generate adequate, actionable data on the costs of primary care services. In this study, we have combined time-motion and available financial data to generate a fee schedule that allows for full cost recovery of the provision of services through billable health education and service encounters provided by Ethiopian HEWs. This may be useful in other country settings where managers seek to make evidence-informed planning and resource allocation decisions to address high burden of disease within the context of weak administrative data systems and severe financial constraints. PMID:29764103
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 4 2012-07-01 2011-07-01 true Assignment to Department of Health, Education, and Welfare (HEW) or successor agencies for health or educational purposes. 644.432 Section 644.432... to Department of Health, Education, and Welfare (HEW) or successor agencies for health or educational...
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 4 2013-07-01 2013-07-01 false Assignment to Department of Health, Education, and Welfare (HEW) or successor agencies for health or educational purposes. 644.432 Section 644.432... to Department of Health, Education, and Welfare (HEW) or successor agencies for health or educational...
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 4 2014-07-01 2013-07-01 true Assignment to Department of Health, Education, and Welfare (HEW) or successor agencies for health or educational purposes. 644.432 Section 644.432... to Department of Health, Education, and Welfare (HEW) or successor agencies for health or educational...
ERIC Educational Resources Information Center
Corson, John J.; And Others
Commissioned to explore the relations between the Department of Health, Education, and Welfare (HEW) and state and local agencies in the field of health, the committee interviewed key HEW administrators, met with state and selected local health officials in nine states and officials of health associations, and invited comments from more than 50…
ERIC Educational Resources Information Center
Gouran, Dennis S.
2009-01-01
This article presents the author's response to Professor Hewes's "The Influence of Communication Processes on Group Outcomes: Antithesis and Thesis." The author believes that Hewes could have been more helpful to the reader and to those who are apt to find inspiration in the steps he has taken in his essay to promote a "return to basic theorizing…
Shaw, Bryan; Amouzou, Agbessi; Miller, Nathan P; Tafesse, Mengistu; Bryce, Jennifer; Surkan, Pamela J
2016-06-01
In 2010, Ethiopia began scaling up the integrated community case management (iCCM) of childhood illness strategy throughout the country allowing health extension workers (HEWs) to treat children in rural health posts. After 2 years of iCCM scale up, utilization of HEWs remains low. Little is known about factors related to the use of health services in this setting. This research aimed to elicit perceptions and experiences of caregivers to better understand reasons for low utilization of iCCM services. A rapid ethnographic assessment was conducted in eight rural health post catchment areas in two zones: Jimma and West Hararghe. In total, 16 focus group discussions and 78 in-depth interviews were completed with mothers, fathers, HEWs and community health volunteers. In spite of the HEW being a core component of iCCM, we found that the lack of availability of HEWs at the health post was one of the most common barriers to the utilization of iCCM services mentioned by caregivers. Financial and geographic challenges continue to influence caregiver decisions despite extension of free child health services in communities. Acceptability of HEWs was often low due to a perceived lack of sensitivity of HEWs and concerns about medicines given at the health post. Social networks acted both to facilitate and hinder use of HEWs. Many mothers stated a preference for using the health post, but some were unable to do so due to objections or alternative care-seeking preferences of gatekeepers, often mothers-in-law and husbands. Caregivers in Ethiopia face many challenges in using HEWs at the health post, potentially resulting in low demand for iCCM services. Efforts to minimize barriers to care seeking and to improve demand should be incorporated into the iCCM strategy in order to achieve reductions in child mortality and promote equity in access and child health outcomes. © The Author 2015. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.
Miller, Nathan P.; Amouzou, Agbessi; Tafesse, Mengistu; Hazel, Elizabeth; Legesse, Hailemariam; Degefie, Tedbabe; Victora, Cesar G.; Black, Robert E.; Bryce, Jennifer
2014-01-01
Ethiopia has scaled up integrated community case management of childhood illness (iCCM) in most regions. We assessed the strength of iCCM implementation and the quality of care provided by health extension workers (HEWs). Data collectors observed HEWs' consultations with sick children and carried out gold standard re-examinations. Nearly all HEWs received training and supervision, and essential commodities were available. HEWs provided correct case management for 64% of children. The proportions of children correctly managed for pneumonia, diarrhea, and malnutrition were 72%, 79%, and 59%, respectively. Only 34% of children with severe illness were correctly managed. Health posts saw an average of 16 sick children in the previous 1 month. These results show that iCCM can be implemented at scale and that community-based HEWs can correctly manage multiple illnesses. However, to increase the chances of impact on child mortality, management of severe illness and use of iCCM services must be improved. PMID:24799369
NASA Astrophysics Data System (ADS)
Citterio, O.; Civitani, M. M.; Pareschi, G.; Basso, S.; Campana, S.; Conconi, P.; Ghigo, M.; Mattaini, E.; Moretti, A.; Parodi, G.; Tagliaferri, G.
2013-09-01
The implementation of a X-ray mission with high imaging capabilities, similar to those achieved with Chandra (< 1 arcsec Half Energy Width, HEW), but with a much larger throughput is a very attractive perspective, even if challenging. For such a mission the scientific opportunities, in particular for the study of the early Universe, would remain at the state of the art for the next decades. At the beginning of the new millennium the XEUS mission has been proposed, with an effective area of several m2 and an angular resolution better than 2 arcsec HEW. Unfortunately, after the initial study, this mission was not implemented, mainly due to the costs and the low level of technology readiness. Currently the most advanced proposal for such a kind of mission is the SMART-X project, led by CfA and involving several other US Institutes. This project is based on adjustable segments of thin foil mirrors with piezo-electric actuators, aiming to achieve an effective area < 2 m2 at 1 keV and an angular resolution better than 1 arcsec HEW. Another attractive technology to realize an X-ray telescope with similar characteristics is being developed at NASA/Goddard. In this case the mirrors are based on Si substrates that are super-polished and figured starting from a bulky Si ingot, from which they are properly cut. Here we propose an alternative method based on precise direct grinding, figuring and polishing of thin (a few mm) glass shells with innovative deterministic polishing methods. This is followed by a final correction via ion figuring to obtain the desired accuracy in order to achieve the 1 arc sec HEW requirement. For this purpose, a temporary stiffening structure is used to support the shell from the polishing operations up to its integration in the telescope supporting structure. We will present the technological process under development, the results achieved so far and some mission scenarios based on this kind of optics, aiming to achieve an effective area more than 10 times larger than Chandra and an angular resolution of 1 arcsec HEW on axis and of a few arcsec off-axis across a large field of view (1 deg in diameter).
HEW to Set Laboratory Safety Standards.
ERIC Educational Resources Information Center
Chemical and Engineering News, 1978
1978-01-01
Describes Department of Health, Education and Welfare (HEW) proposed guidelines for laboratories using chemical carcinogens. The guidelines are designed to provide protection for laboratory workers and their environment from exposure to all types of carcinogenic agents. (GA)
The HEW Review of Educational Services to New York's Minority Children
ERIC Educational Resources Information Center
Gerry, Martin
1975-01-01
Testimony before a public hearing of the New York City Commission on Human Rights in May 1974 by the project director of a projected in-depth review of the delivery of educational services to over 700,000 minority children attending the New York City Public School system asserted to be the largest civil rights review of its kind in U.S. history.…
HEW and the neurologically handicapped
NASA Technical Reports Server (NTRS)
Huber, W. V.
1974-01-01
Some of the neurological disorders and therapeutic devices are considered with which the Department of Health, Education, and Welfare (HEW) is most concerned. The organization of the Department, because it is a rather complex one with many different agencies involved, is also described.
1969-09-24
Donald Hewes at Lunar Landing Research Facility (LLRF). Donald Hewes, head of the Spacecraft Research Branch, managed the facility. Piles of cinders simulated the lunar craters and terrain features. Published in the book " A Century at Langley" by Joseph Chambers. pg. 97
Responsibility and Responsiveness. The HEW Potential for the Seventies.
ERIC Educational Resources Information Center
Richardson, Elliot L.
The Secretary of HEW presents an overview of departmental undertakings for the purpose of developing more responsible and responsive personnel. The major portion of the statement focuses on internal processes of responsibility and external processes of responsiveness. Departmental strategies, a planning cycle, an operational planning system,…
"'It's the Camaraderie': A History of Parent Cooperative Preschools," by Dorothy Hewes. Book Review.
ERIC Educational Resources Information Center
Hinitz, Blythe
2000-01-01
Reviews Hewes' book on the development of the parent cooperative nursery school movement in its political, sociological, economic, and historical contexts. Notes the success of the organizational model used to analyze the movement and the book's value as a reference work. (JPB)
An Evaluation of Performance Contracting for HEW.
ERIC Educational Resources Information Center
Carpenter, Polly
This speech provides a summary of the Rand/HEW study of eight performance contract programs in the five cities of Gilroy, California; Texarkana, Arkansas; Gary, Indiana; Grand Rapids, Michigan; and Norfolk, Virginia. The effects of performance contracting on instruction and on student learning, the program costs and management, the contractors,…
NASA Astrophysics Data System (ADS)
Pareschi, Giovanni; Citterio, Oberto; Civitani, Marta M; Basso, Stefano; Campana, Sergio; Conconi, Paolo; Ghigo, Mauro; Mattaini, Enrico; Moretti, Alberto; Parodi, Giancarlo; Tagliaferri, Gianpiero
2014-08-01
The implementation of an X-ray mission with high imaging capabilities, similar to those achieved with Chandra (<1 arcsec Half Energy Width, HEW), but with a much larger throughput is very attractive, even if challenging. For such a mission the scientific opportunities, in particular for the study of the early Universe, would remain at the state of the art for the next decades. Initially the ESA-led XEUS mission was proposed, with an effective area of several m2 and an angular resolution better than 2 arcsec HEW. Unfortunately, this mission was not implemented, mainly due to the costs and the low level of technology readiness. Currently the most advanced proposal for such a mission is the SMART-X project, led by CfA together with other US institutes. This project is based on adjustable segments of thin foil mirrors with piezo-electric actuators, aiming to achieve an effective area >2 m2 at 1 keV and an angular resolution better than 1 arcsec HEW. Another attractive technology to realize an X-ray telescope with similar characteristics is being developed at NASA/Goddard. In this case the mirrors are based on Si substrates that are super-polished and figured starting from a bulky Si ingot, from which they are properly cut. Here we propose an alternative method based on precise direct grinding, figuring and polishing of thin (a few mm) glass shells with innovative deterministic polishing methods. This is followed by a final correction via ion figuring to obtain the desired accuracy. For this purpose, a temporary stiffening structure is used to support the shell from the polishing operations up to its integration in the telescope supporting structure. This paper deals with the technological process under development, the results achieved so far and some mission scenarios based on this kind of optics, aiming to achieve an effective area more than 10 times larger than Chandra and an angular resolution of 1 arcsec HEW on axis and of a few arcsec off-axis across a large field of view (1o in diameter).
Head Start/EPSDT Collaboration Evaluation. Final Report.
ERIC Educational Resources Information Center
Boone, Young and Associates, Inc., New York, NY.
This is the final report on the first year evaluation of the Head Start/Medicaid Early and Periodic Screening, Diagnosis and Treatment (EPSDT) Collaborative Effort, a demonstration program that was initiated by the Office of Child Development OCD/HEW in 1974. In initiating the program, OCD/HEW set forth the following objectives: (1) to assess the…
ERIC Educational Resources Information Center
Congress of the U. S., Washington, DC. House Committee on Government Operations.
Three hearings held before the U.S. House of Representatives on student financial assistance programs were concerned with the manner in which the Office of Education's assistance programs were being administered, the extent and nature of fraud, waste and abuse, and the progress of the Department of Health, Education, and Welfare's (HEW) corrective…
Accelerated shelf-life testing of quality loss for a commercial hydrolysed hen egg white powder.
Rao, Qinchun; Rocca-Smith, Jeancarlo R; Schoenfuss, Tonya C; Labuza, Theodore P
2012-11-15
In recent years, due to the specific health benefits associated with bioactive peptides and the reduction of protein allergenicity by enzymatic hydrolysis, the utilisation of protein hydrolysates in functional foods and beverages for both protein supplementation and clinical use has significantly increased. However, few studies have explored the moisture-induced effects on food protein hydrolysates, and the resulting changes in the structure and texture of the food matrix as well as the loss in functional properties of bioactive peptides during storage. The main purpose of this study is to determine the influence of water activity (a(w)) on the storage quality of a commercial spray-dried hydrolysed hen egg white powder (HEW). During storage at 45 °C for two months at different a(w)s (0.05-0.79), the selected physicochemical properties of the HEW samples were analysed. Overall, the effect of a(w) on the colour change of HEW at 45 °C for one month was similar to that of HEW after four months at 23 °C due to the presence of a small amount of glucose in HEW. Several structural changes occurred at a(w)s from 0.43 to 0.79 including agglomeration, stickiness and collapse. Kinetic analysis showed a first-order hyperbolic model fit for the change in the L(∗) value, the total colour difference (ΔE(∗)) and the fluorescence intensity (FI). There was a high correlation between colour change and fluorescence, as expected for the Maillard reaction. The reduction in the remaining free amino groups was about 5% at a(w) 0.50 and 6% at a(w) 0.79 after one month storage. In summary, during storage, the Maillard reaction and/or its resulting products could decrease the nutritional value and the quality of HEW. Copyright © 2012 Elsevier Ltd. All rights reserved.
Delinquency Level Classification Via the HEW Community Program Youth Impact Scales.
ERIC Educational Resources Information Center
Truckenmiller, James L.
The former HEW National Strategy for Youth Development (NSYD) model was created as a community-based planning and procedural tool to promote youth development and prevent delinquency. To assess the predictive power of NSYD Impact Scales in classifying youths into low, medium, and high delinquency levels, male and female students aged 10-19 years…
ERIC Educational Resources Information Center
Truckenmiller, James L.
The former HEW National Strategy for Youth Development model was a community-based planning and procedural tool to enhance and to prevent delinquency through a process of youth needs assessments, needs targeted programs, and program impact evaluation. The program's 12 Impact Scales have been found to have acceptable reliabilities, substantial…
Press Conference with Elliot L. Richardson, Secretary of HEW.
ERIC Educational Resources Information Center
Department of Health, Education, and Welfare, Washington, DC.
Two documents were released to the press on January 18, 1973, by Secretary Richardson, one summarizing his term of office as Secretary of Health, Education, and Welfare, and one reporting on HEW potential for the seventies (SO 005 666, SO 005 699). In an introductory statement prior to the press conference, the question of whether or not we as a…
ERIC Educational Resources Information Center
Truckenmiller, James L.
The former HEW National Strategy for Youth Development Model was a community-based planning and procedural tool designed to enhance positive youth development and prevent delinquency through a process of youth needs assessment, development of targeted programs, and program impact evaluation. A series of 12 Impact Scales most directly reflect the…
NASA Stennis hosts 2010 NASA Day at the Capitol.
NASA Technical Reports Server (NTRS)
2010-01-01
Astronaut Danny Olivas (center) speaks to members of the Mississippi Senate in chambers during NASA Day at the Capitol in Jackson on Jan. 6. Olivas was joined at the podium by Stennis Deputy Director Patrick Scheuermann (standing, l to r), Sen. David Baria, D-Bay St. Louis, and Sen. Billy Hewes, R-Gulfport. Baria and Hewes both are members of the Mississippi Senate Gulf Coast delegation.
New model for Jurassic microcontinent movement and Gondwana breakup in the Weddell Sea region
NASA Astrophysics Data System (ADS)
Jordan, Tom; Ferraccioli, Fausto; Leat, Philip
2017-04-01
The breakup of the Gondwana supercontinent changed the face of our planet. Precursors of supercontinental breakup are widely recognised in the Weddell Sea region in the Jurassic. These include the Karoo/Ferrar Large Igneous Province that extends from South Africa to East Antarctica and significant continental rifting and associated translation of microcontinental blocks in the Weddell Sea Embayment region. However, significant controversy surrounds the pre-breakup position, extent, timing and driving mechanism of inferred microcontinental movement. In particular geological and paleomagnetic data suggest >1000 km of translation and 90 degree rotation of the Haag-Ellsworth Whitmore block (HEW) away from East Antarctica. In contrast, some geophysical interpretations suggest little or no Jurassic or subsequent HEW block movement. Here we present a simpler tectonic model for the Weddell Sea Rift System and HEW movement, derived from our new compilation of airborne geophysical data, satellite magnetic data and potential field modelling (Jordan et al., 2016- Gondwana Res.). Based on the amount of inferred Jurassic crustal extension and pattern of magnetic anomalies we propose that the HEW was translated 500 km towards the Paleo-Pacific margin of Gondwana, possibly in response to a process of slab roll-back that led to distributed back-arc extension in the Weddell Sea Rift System. Widespread magmatism in the region was likely influenced by the presence of one or more mantle plumes impinging beneath the stretching lithosphere. A second phase of continental extension is inferred to have occurred between 180 and 165 Ma (prior to seafloor spreading) and is more closely associated with Gondwana breakup. This second phase over-printed the northern part of the older back arc system. We find no geophysical evidence indicating more than 30 degrees of syn-extensional HEW rotation during Jurassic rifting in the southern Weddell Sea Rift System. Instead, we propose the majority ( 60 degrees) of the inferred block rotation of the HEW sedimentary sequences occurred prior to Jurassic rifting, likely during the Permian-age Gondwanide orogeny as a phase of oroclinal bending in an overall transpressional intraplate orogenic setting.
ERIC Educational Resources Information Center
Truckenmiller, James L.
The Health, Education and Welfare (HEW) Office of Youth Development's National Strategy for Youth Development model was promoted as a community-based planning and procedural tool for enhancing positive youth development and reducing delinquency. To test the applicability of the model as a function of delinquency level, the program's Impact Scales…
Abé, Christoph; Rahman, Qazi; Långström, Niklas; Rydén, Eleonore; Ingvar, Martin; Landén, Mikael
2018-05-29
Nonheterosexual individuals have higher risk of psychiatric morbidity. Together with growing evidence for sexual orientation-related brain differences, this raises the concern that sexual orientation may be an important factor to control for in neuroimaging studies of neuropsychiatric disorders. We studied sexual orientation in adult psychiatric patients with bipolar disorder (BD) or ADHD in a large clinical cohort (N = 154). We compared cortical brain structure in exclusively heterosexual women (HEW, n = 29) with that of nonexclusively heterosexual women (nHEW, n = 37) using surface-based reconstruction techniques provided by FreeSurfer. The prevalence of nonheterosexual sexual orientation was tentatively higher than reported in general population samples. Consistent with previously reported cross-sex shifted brain patterns among homosexual individuals, nHEW patients showed significantly larger cortical volumes than HEW in medial occipital brain regions. We found evidence for a sex-reversed difference in cortical volume among nonheterosexual female patients, which provides insights into the neurobiology of sexual orientation, and may provide the first clues toward a better neurobiological understanding of the association between sexual orientation and mental health. We also suggest that sexual orientation is an important factor to consider in future neuroimaging studies of populations with certain mental health disorders. © 2018 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Committee on Labor and Public Welfare.
A proposal up for consideration before the United States Senate is discussed. The program suggested is a redesign of the Department of Health, Education, and Welfare in keeping with the principles of the New Federalism. The proposal touches every major area of HEW policy: it simplifies the Department's program structure; it narrows and focuses the…
2011-02-10
Astronaut Steven Swanson (front) speaks to members of the Mississippi Senate in chambers, with Lt. Gov. Phil Bryant presiding (rear), during NASA Day at the Capitol in Jackson on Feb. 10. Swanson was joined at the podium by Sen. David Baria, D-Bay St. Louis (l to r), NASA Shared Services Center Executive Director Rick Arbuthnot, Stennis Director Patrick Scheuermann, Sen. Ezell Lee, D-Picayune, and Sen. Billy Hewes, R-Gulfport. Baria, Lee and Hewes all are members of the Mississippi Senate Gulf Coast delegation.
Jackson, Ruth; Hailemariam, Assefa
2016-09-01
Women's preference to give birth at home is deeply embedded in Ethiopian culture. Many women only go to health facilities if they have complications during birth. Health Extension Workers (HEWs) have been deployed to improve the utilization of maternal health services by bridging the gap between communities and health facilities. This study examined the barriers and facilitators for HEWs as they refer women to mid-level health facilities for birth. A qualitative study was conducted in three regions: Afar Region, Southern Nations Nationalities and People's Region and Tigray Region between March to December 2014. Interviews and focus group discussions were conducted with 45 HEWs, 14 women extension workers (employed by Afar Pastoralist Development Association, Afar Region) and 11 other health workers from health centers, hospitals or health offices. Data analysis was done based on collating the data and identifying key themes. Barriers to health facilities included distance, lack of transportation, sociocultural factors and disrespectful care. Facilitators for facility-based deliveries included liaising with Health Development Army (HDA) leaders to refer women before their expected due date or if labour starts at home; the introduction of ambulance services; and, provision of health services that are culturally more acceptable for women. HEWs can effectively refer more women to give birth in health facilities when the HDA is well established, when health staff provide respectful care, and when ambulance is available at any time.
Understanding modern contraception uptake in one Ethiopian community: a case study.
Sedlander, Erica; Bingenheimer, Jeffrey B; Edberg, Mark C; Rimal, Rajiv N; Shaikh, Hina; Munar, Wolfgang
2018-06-20
In the last decade, the proportion of Ethiopian women using contraceptive methods has increased substantially (from 14% in 2005 to 35% in 2016 among married women). Numerous factors have contributed to the increased uptake. An important one is the implementation of the Health Extension Program, a government-led health service delivery strategy that has deployed more than 38,000 health extension workers (HEWs) throughout the country. Key mechanisms underlying the success of this program are not well understood. Using a case study approach, the goal of this study is to describe how key features of local contexts, community perceptions, and messaging by HEWs have contributed to the increased use of modern contraception in one community in Ethiopia. We conducted focus groups and individual interviews with men, women, adolescents, and key informants, including (HEWs), in Oromia, Ethiopia. We used a random sampling protocol to recruit all participants except key informants, with whom purposive sampling was used to ensure participants were knowledgeable on family planning in the village. Interviews were audio recorded, translated, transcribed, and then analyzed using applied thematic analysis and NVivo v.11 qualitative research software. We identified four themes that may explain uptake of contraception: (1) HEWs are seen as trusted and valued community members who raised awareness about family planning; (2) the HEW messaging that contraception is useful to space pregnancies among married women was effective; (3) the message that spacing is healthy for mother and child was also effective; and (4) communicating to the entire community (including men, women, adolescents, and religious leaders), contributed to changing attitudes around contraception. The four aspects of the Health Extension Program approach increased uptake of contraception in our sample. In contexts where community health workers are valued by the health systems and local communities they serve, this type of approach to widening modern contraception use could help increase uptake and address unmet need. Understanding these granular aspects of the program in one local context may help explain how use of contraception increased in the country as a whole.
Increasing Access to Tuberculosis Services in Ethiopia: Findings From a Patient-Pathway Analysis.
Fekadu, Lelisa; Hanson, Christy; Osberg, Mike; Makayova, Julia; Mingkwan, Pia; Chin, Daniel
2017-11-06
In Ethiopia, extensive scale-up of the availability of health extension workers (HEWs) at the community level has been credited with increased identification and referral of patients with presumptive tuberculosis, which has contributed to increased tuberculosis case notification and better treatment outcomes. However, nearly 30% of Ethiopia's estimated 191000 patients with tuberculosis remained unnotified in 2015. A better understanding of patient care-seeking practices may inform future government action to reach all patients with tuberculosis. A patient-pathway analysis was completed to assess the alignment between patient care initiation and the availability of diagnostic and treatment services at the national level. More than one third of patients initiated care with HEWs, who refer patients to health centers for diagnosis. An additional one third of patients initiated care at health centers. Of those health centers, >80% had microscopy services, but few had access to Xpert. Despite an extensive microscopy and radiography network at middle levels of the health system, a quarter of all notified patients with tuberculosis had no bacteriological confirmation of disease. While 30% of patients reported receiving some form of care from the private sector, private-sector facilities, especially pharmacies, were not widely accessed for tuberculosis diagnosis. The availability of HEWs can increase access to tuberculosis diagnostic and treatment support services, particularly for rural populations. Continued strengthening of referral systems from HEWs and health posts are needed to enable consistent and timely access to Xpert as an initial diagnostic test and to drug resistance screening. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.
Dusabe-Richards, John N; Tesfaye, Hayley Teshome; Mekonnen, Jarso; Kea, Aschenaki; Theobald, Sally; Datiko, Daniel G
2016-12-27
This study assesses the feasibility of female health extension workers (HEWs) using eHealth within their core duties, supporting both the design and capacity building for an eHealth system project focussed initially on tuberculosis, maternal child health, and gender equity. Health extension workers, Health Centre Heads, District Health Officers, Zonal Health Department and Regional Health Bureau representatives in Southern Ethiopia. The study was undertaken in Southern Ethiopia with three districts in Sidama zone (population of 3.5 million) and one district in Gedeo zone (control zone with similar health service coverage and population density). Mixed method baseline data collection was undertaken, using quantitative questionnaires (n = 57) and purposively sampled qualitative face-to-face semi-structured interviews (n = 10) and focus group discussions (n = 3). Themes were identified relating to HEW commitment and role, supervision, and performance management. The Health Management Information System (HMIS) was seen as important by all participants, but with challenges of information quality, accuracy, reliability and timeliness. Participants' perceptions varied by group regarding the purpose and benefits of HMIS as well as the potential of an eHealth system. Mobile phones were used regularly by all participants. eHealth technology presents a new opportunity for the Ethiopian health system to improve data quality and community health. Front-line female HEWs are a critical bridge between communities and health systems. Empowering HEWs, supporting them and responding to the challenges they face will be an important part of ensuring the sustainability and responsiveness of eHealth strategies. Findings have informed the subsequent eHealth technology design and implementation, capacity strengthening approach, supervision, and performance management approach.
Sexual orientation related differences in cortical thickness in male individuals.
Abé, Christoph; Johansson, Emilia; Allzén, Elin; Savic, Ivanka
2014-01-01
Previous neuroimaging studies demonstrated sex and also sexual orientation related structural and functional differences in the human brain. Genetic information and effects of sex hormones are assumed to contribute to the male/female differentiation of the brain, and similar effects could play a role in processes influencing human's sexual orientation. However, questions about the origin and development of a person's sexual orientation remain unanswered, and research on sexual orientation related neurobiological characteristics is still very limited. To contribute to a better understanding of the neurobiology of sexual orientation, we used magnetic resonance imaging (MRI) in order to compare regional cortical thickness (Cth) and subcortical volumes of homosexual men (hoM), heterosexual men (heM) and heterosexual women (heW). hoM (and heW) had thinner cortices primarily in visual areas and smaller thalamus volumes than heM, in which hoM and heW did not differ. Our results support previous studies, which suggest cerebral differences between hoM and heM in regions, where sex differences have been reported, which are frequently proposed to underlie biological mechanisms. Thus, our results contribute to a better understanding of the neurobiology of sexual orientation.
Tachibana, M; Koizumi, H; Kojima, K
2004-05-01
Longitudinal sound velocity of tetragonal hen-egg-white (HEW) lysozyme crystals was measured during air drying by ultrasonic pulseecho method. The sound velocity increases with exposure to open air and approaches a constant value. The maximum value is approximately 2900 m/s that is about 1.6 times as much as that of original one before drying. In addition, the sound velocity clearly recovers to original one after immersing the dried crystal in solution. Therefore, the sound velocity in tetragonal HEW lysozyme crystals can be reversibly changed due to dehydration and rehydration. These changes in sound velocity are discussed in the light of water-mediated intramolecular and intermolecular interactions in the crystals.
NASA Astrophysics Data System (ADS)
Tachibana, M.; Koizumi, H.; Kojima, K.
2004-05-01
Longitudinal sound velocity of tetragonal hen-egg-white (HEW) lysozyme crystals was measured during air drying by ultrasonic pulseecho method. The sound velocity increases with exposure to open air and approaches a constant value. The maximum value is ˜2900 m/s that is about 1.6 times as much as that of original one before drying. In addition, the sound velocity clearly recovers to original one after immersing the dried crystal in solution. Therefore, the sound velocity in tetragonal HEW lysozyme crystals can be reversibly changed due to dehydration and rehydration. These changes in sound velocity are discussed in the light of water-mediated intramolecular and intermolecular interactions in the crystals.
Iterative management of heat early warning systems in a changing climate.
Hess, Jeremy J; Ebi, Kristie L
2016-10-01
Extreme heat is a leading weather-related cause of morbidity and mortality, with heat exposure becoming more widespread, frequent, and intense as climates change. The use of heat early warning and response systems (HEWSs) that integrate weather forecasts with risk assessment, communication, and reduction activities is increasingly widespread. HEWSs are frequently touted as an adaptation to climate change, but little attention has been paid to the question of how best to ensure effectiveness of HEWSs as climates change further. In this paper, we discuss findings showing that HEWSs satisfy the tenets of an intervention that facilitates adaptation, but climate change poses challenges infrequently addressed in heat action plans, particularly changes in the onset, duration, and intensity of dangerously warm temperatures, and changes over time in the relationships between temperature and health outcomes. Iterative management should be central to a HEWS, and iteration cycles should be of 5 years or less. Climate change adaptation and implementation science research frameworks can be used to identify HEWS modifications to improve their effectiveness as temperature continues to rise, incorporating scientific insights and new understanding of effective interventions. We conclude that, at a minimum, iterative management activities should involve planned reassessment at least every 5 years of hazard distribution, population-level vulnerability, and HEWS effectiveness. © 2016 New York Academy of Sciences.
Datiko, Daniel G; Yassin, Mohammed A; Theobald, Sally J; Blok, Lucie; Suvanand, Sahu; Creswell, Jacob
2017-01-01
Background Tuberculosis (TB) is a major cause of death in Ethiopia. One of the main barriers for TB control is the lack of access to health services. Methods We evaluated a diagnostic and treatment service for TB based on the health extension workers (HEW) of the Ethiopian Health Extension Programme in Sidama Zone, with 3.5 million population. We added the services to the HEW routines and evaluated their effect over 4.5 years. 1024 HEWs were trained to identify individuals with symptoms of TB, request sputum samples and prepare smears. Smears were transported to designated laboratories. Individuals with TB were offered treatment at home or the local health post. A second zone (Hadiya) with 1.2 million population was selected as control. We compared TB case notification rates (CNR) and treatment outcomes in the zones 3 years before and 4.5 years after intervention. Results HEWs identified 216 165 individuals with symptoms and 27 918 (12%) were diagnosed with TB. Smear-positive TB CNR increased from 64 (95% CI 62.5 to 65.8) to 127 (95% CI 123.8 to 131.2) and all forms of TB increased from 102 (95% CI 99.1 to 105.8) to 177 (95% CI 172.6 to 181.0) per 100 000 population in the first year of intervention. In subsequent years, the smear-positive CNR declined by 9% per year. There was no change in CNR in the control area. Treatment success increased from 76% before the intervention to 95% during the intervention. Patients lost to follow-up decreased from 21% to 3% (p<0.001). Conclusion A community-based package significantly increased case finding and improved treatment outcome. Implementing this strategy could help meet the Ethiopian Sustainable Development Goal targets. PMID:29209537
Jackson, Ruth; Tesfay, Fisaha Haile; Godefay, Hagos; Gebrehiwot, Tesfay Gebregzabher
2016-01-01
The maternal health system in Ethiopia links health posts in rural communities (kebeles) with district (woreda) health centres, and health centres with primary hospitals. At each health post two Health Extension Workers (HEWs) assist women with birth preparedness, complication readiness, and mobilize communities to facilitate timely referral to mid-level service providers. This study explored HEWs' and mother's attitudes to maternal health services in Adwa Woreda, Tigray Region. In this qualitative study, we trained 16 HEWs to interview 45 women to gain a better understanding of the social context of maternal health related behaviours. Themes included barriers to health services; women's social status and mobility; and women's perceptions of skilled birth attendant's care. All data were analyzed thematically. There have been substantial efforts to improve maternal health and reduce maternal mortality in Adwa Woreda. Women identified barriers to healthcare including distance and lack of transportation due to geographical factors; the absence of many husbands due to off-woreda farming; traditional factors such as zwar (some pregnant women are afraid of meeting other pregnant women), and discouragement from mothers and mothers-in-law who delivered their children at home. Some women experienced disrespectful care at the hospital. Facilitators to skilled birth attendance included: identification of pregnant women through Women's Development Groups (WDGs), and referral by ambulance to health facilities either before a woman's Expected Due Date (EDD) or if labour started at home. With the support of WDGs, HEWs have increased the rate of skilled birth attendance by calling ambulances to transfer women to health centres either before their EDD or when labour starts at home. These findings add to the growing body of evidence that health workers at the community level can work with women's groups to improve maternal health, thus reducing the need for emergency obstetric care in low-income countries.
A natural and readily available crowding agent: NMR studies of proteins in hen egg white.
Martorell, Gabriel; Adrover, Miquel; Kelly, Geoff; Temussi, Piero Andrea; Pastore, Annalisa
2011-05-01
In vitro studies of biological macromolecules are usually performed in dilute, buffered solutions containing one or just a few different biological macromolecules. Under these conditions, the interactions among molecules are diffusion limited. On the contrary, in living systems, macromolecules of a given type are surrounded by many others, at very high total concentrations. In the last few years, there has been an increasing effort to study biological macromolecules directly in natural crowded environments, as in intact bacterial cells or by mimicking natural crowding by adding proteins, polysaccharides, or even synthetic polymers. Here, we propose the use of hen egg white (HEW) as a simple natural medium, with all features of the media of crowded cells, that could be used by any researcher without difficulty and inexpensively. We present a study of the stability and dynamics behavior of model proteins in HEW, chosen as a prototypical, readily accessible natural medium that can mimic cytosol. We show that two typical globular proteins, dissolved in HEW, give NMR spectra very similar to those obtained in dilute buffers, although dynamic parameters are clearly affected by the crowded medium. The thermal stability of one of these proteins, measured in a range comprising both heat and cold denaturation, is also similar to that in buffer. Our data open new possibilities to the study of proteins in natural crowded media. Copyright © 2010 Wiley-Liss, Inc.
NASA Astrophysics Data System (ADS)
Wang, X.; Liu, T.; Li, R.; Yang, X.; Duan, L.; Luo, Y.
2012-12-01
Wetlands are one of the most important watershed microtopographic features that affect, in combination rather than individually, hydrologic processes (e.g., routing) and the fate and transport of constituents (e.g., sediment and nutrients). Efforts to conserve existing wetlands and/or to restore lost wetlands require that watershed-level effects of wetlands on water quantity and water quality be quantified. Because monitoring approaches are usually cost or logistics prohibitive at watershed scale, distributed watershed models, such as the Soil and Water Assessment Tool (SWAT), can be a best resort if wetlands can be appropriately represented in the models. However, the exact method that should be used to incorporate wetlands into hydrologic models is the subject of much disagreement in the literature. In addition, there is a serious lack of information about how to model wetland conservation-restoration effects using such kind of integrated modeling approach. The objectives of this study were to: 1) develop a "hydrologic equivalent wetland" (HEW) concept; and 2) demonstrate how to use the HEW concept in SWAT to assess effects of wetland restoration within the Broughton's Creek watershed located in southwestern Manitoba of Canada, and of wetland conservation within the upper portion of the Otter Tail River watershed located in northwestern Minnesota of the United States. The HEWs were defined in terms of six calibrated parameters: the fraction of the subbasin area that drains into wetlands (WET_FR), the volume of water stored in the wetlands when filled to their normal water level (WET_NVOL), the volume of water stored in the wetlands when filled to their maximum water level (WET_MXVOL), the longest tributary channel length in the subbasin (CH_L1), Manning's n value for the tributary channels (CH_N1), and Manning's n value for the main channel (CH_N2). The results indicated that the HEW concept allows the nonlinear functional relations between watershed processes and wetland characteristics (e.g., size and morphology) to be accurately represented in the models. The loss of the first 10 to 20% of the wetlands in the Minnesota study area would drastically increase the peak discharge and loadings of sediment, total phosphorus (TP), and total nitrogen (TN). On the other hand, the justifiable reductions of the peak discharge and loadings of sediment, TP, and TN in the Manitoba study area may require that 50 to 80% of the lost wetlands be restored. Further, the comparison between the predicted restoration and conservation effects revealed that wetland conservation seems to deserve a higher priority while both wetland conservation and restoration may be equally important. Moreover, although SWAT was used in this study, the HEW concept is generic and can also be applied with any other hydrologic models.
Community-Based Interventions for Newborns in Ethiopia (COMBINE): Cost-effectiveness analysis.
Mathewos, Bereket; Owen, Helen; Sitrin, Deborah; Cousens, Simon; Degefie, Tedbabe; Wall, Stephen; Bekele, Abeba; Lawn, Joy E; Daviaud, Emmanuelle
2017-10-01
About 87 000 neonates die annually in Ethiopia, with slower progress than for child deaths and 85% of births are at home. As part of a multi-country, standardized economic evaluation, we examine the incremental benefit and costs of providing management of possible serious bacterial infection (PSBI) for newborns at health posts in Ethiopia by Health Extension Workers (HEWs), linked to improved implementation of existing policy for community-based newborn care (Health Extension Programme). The government, with Save the Children/Saving Newborn Lives and John Snow, Inc., undertook a cluster randomized trial. Both trial arms involved improved implementation of the Health Extension Programme. The intervention arm received additional equipment, support and supervision for HEWs to identify and treat PSBI. In 2012, ∼95% of mothers in the study area received at least one pregnancy or postnatal visit in each arm, an average of 5.2 contacts per mother in the intervention arm (4.9 in control). Of all visits, 79% were conducted by volunteer community health workers. HEWs spent around 9% of their time on the programme. The financial cost per mother and newborn was $34 (in 2015 USD) in the intervention arm ($27 in control), economic costs of $37 and $30, respectively. Adding PSBI management at community level was estimated to reduce neonatal mortality after day 1 by 17%, translating to a cost per DALY averted of $223 or 47% of the GDP per capita, a highly cost-effective intervention by WHO thresholds. In a routine situation, the intervention programme cost would represent 0.3% of public health expenditure per capita and 0.5% with additional monthly supervision meetings. A platform wide approach to improved supervision including a dedicated transport budget may be more sustainable than a programme-specific approach. In this context, strengthening the existing HEW package is cost-effective and also avoids costly transfers to health centres/hospitals. © The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
HEW Proposals Open Door for Ms. Jock
ERIC Educational Resources Information Center
Klopfer, Susan
1974-01-01
Discusses the increased demand for women's sports programs as reflected in student publications following the signing of Title 9 of the Education Amendments Act which prohibits sex bias in federally financed education programs. (RB)
The Oral Provocation Test for Raw Egg in Patients with Hen Egg Allergy.
Kido, Jun; Nishi, Natsuko; Matsumoto, Tomoaki
2018-06-06
Many researchers have made efforts to develop diagnostic tools for predicting the outcome of oral food challenges (OFCs). The aim of this study was to assess the diagnostic value of the skin prick test (SPT) and blood-specific IgE concentrations based on the outcome of the OFCs for heated and raw hen egg. This study included 103 children with suspected hen egg allergy (HEA; median age 23 months, range 10-155; 72 boys, 31 girls). Forty-three patients were diagnosed with HEA by OFC. Of 60 patients who tolerated heated egg white (HEW), 22 underwent the OFC for raw hen egg and 7 developed adverse reactions after ingesting raw egg. Their wheal diameters and specific IgE levels for egg white and ovomucoid were determined. Wheal diameters as well as blood-specific IgE levels for egg white and ovomucoid were significantly larger in children with positive OFC results for HEW than in those with negative results. However, there were no significant differences between the positive and negative test results for raw hen egg white (REW) in wheal diameter or blood-specific IgE levels. The SPT and blood-specific IgE can be used to diagnose HEA. However, the provocation test for REW in children without HEW allergy is important because the values of SPT and specific IgE were not significantly different between children with and without raw egg allergy. © 2018 S. Karger AG, Basel.
Simbol-X Hard X-ray Focusing Mirrors: Results Obtained During the Phase A Study
NASA Astrophysics Data System (ADS)
Tagliaferri, G.; Basso, S.; Borghi, G.; Burkert, W.; Citterio, O.; Civitani, M.; Conconi, P.; Cotroneo, V.; Freyberg, M.; Garoli, D.; Gorenstein, P.; Hartner, G.; Mattarello, V.; Orlandi, A.; Pareschi, G.; Romaine, S.; Spiga, D.; Valsecchi, G.; Vernani, D.
2009-05-01
Simbol-X will push grazing incidence imaging up to 80 keV, providing a strong improvement both in sensitivity and angular resolution compared to all instruments that have operated so far above 10 keV. The superb hard X-ray imaging capability will be guaranteed by a mirror module of 100 electroformed Nickel shells with a multilayer reflecting coating. Here we will describe the technogical development and solutions adopted for the fabrication of the mirror module, that must guarantee an Half Energy Width (HEW) better than 20 arcsec from 0.5 up to 30 keV and a goal of 40 arcsec at 60 keV. During the phase A, terminated at the end of 2008, we have developed three engineering models with two, two and three shells, respectively. The most critical aspects in the development of the Simbol-X mirrors are i) the production of the 100 mandrels with very good surface quality within the timeline of the mission, ii) the replication of shells that must be very thin (a factor of 2 thinner than those of XMM-Newton) and still have very good image quality up to 80 keV, iii) the development of an integration process that allows us to integrate these very thin mirrors maintaining their intrinsic good image quality. The Phase A study has shown that we can fabricate the mandrels with the needed quality and that we have developed a valid integration process. The shells that we have produced so far have a quite good image quality, e.g. HEW <~30 arcsec at 30 keV, and effective area. However, we still need to make some improvements to reach the requirements. We will briefly present these results and discuss the possible improvements that we will investigate during phase B.
X-ray optical units made of glass: achievements and perspectives
NASA Astrophysics Data System (ADS)
Civitani, M.; Basso, S.; Ghigo, M.; Pareschi, G.; Salmaso, B.; Spiga, D.; Tagliaferri, G.; Vecchi, G.; Burwitz, V.; Hartner, G. D.; Menz, B.
2014-07-01
Future X-ray telescopes with very large collecting area, like the proposed Athena with more than 2 m2 effective area at 1 keV, need to be realized as assemblies of a large number of X-ray optical units, named X-ray Optical Units (XOUs). The Brera Astronomical Observatory (INAF-OAB) is developing a new technology to manufacture these modular elements, compatible with an angular resolution of 5 arcsec HEW (Half-Energy-Width). This technique consists in stacking in a Wolter-I configuration several layers of thin foils of glass, previously formed by direct hot slumping. The achievable global angular resolution of the optics relies on the required surface shape accuracy of slumped foils, on the smoothness of the mirror surfaces and on the correct integration and co-alignment of the mirror segments operated trough a dedicated Integration Machine (IMA). In this paper we provide an overview of the project development, reporting on the very promising results achieved so far, including in-focus full illumination X-ray tests of the prototype (Proof of Concept, POC#2, integrated at the beginning of 2013) for which an HEW of 22.1'' has been measured at Panter/MPE. Moreover we report on the on-going activities, with a new integrated prototype (PoC#3). X-ray test in pencil beam revealed that at least a segment between two external ribs is characterized by an HEW well below 10''. Lastly, the overall process up-grade to go from 20 m to 12m focal length (to be compatible with Athena+ configuration) is presented.
32 CFR 644.483 - Notification of Department of HEW or successor agencies.
Code of Federal Regulations, 2010 CFR
2010-07-01
... not needed for school, classroom, or other educational use or for use in the protection of public health, including research. If within the 20-day period, notice is received of a potential need, the...
Afework, Mesganaw Fantahun; Admassu, Kesteberhan; Mekonnen, Alemayehu; Hagos, Seifu; Asegid, Meselech; Ahmed, Saifuddin
2014-04-04
Among Millennium Development Goals, achieving the fifth goal (MDG-5) of reducing maternal mortality poses the greatest challenge in Sub-Saharan Africa. Ethiopia has one of the highest maternal mortality ratios in the world with unacceptably low maternal health service utilization. The Government of Ethiopia introduced an innovative community-based intervention as a national strategy under the Health Sector Development Program. This new approach, known as the Health Extension Program, aims to improve access to and equity in essential health services through community based Health Extension Workers. The objective of the study is to assess the role of Health Extension Workers in improving women's utilization of antenatal care, delivery at health facility and postnatal care services. A cross sectional household survey was conducted in early 2012 in two districts of northern and south central parts of Ethiopia. Data were collected from 4949 women who had delivered in the two years preceding the survey. Logistic regression analysis was performed to determine the association between visit by Health Extension Workers during pregnancy and use of maternal health services, controlling for the effect of other confounding factors. The non-adjusted analysis showed that antenatal care attendance at least four times during pregnancy was significantly associated with visit by Health Extension Workers [Odds Ratio 3.46(95% CI 3.07,3.91)], whereas health facility delivery (skilled attendance at birth) was not significantly associated with visit by Health Extension Workers during pregnancy [Odds Ratio 0.87(95% CI 0.25,2.96)]. When adjusted for other factors the association of HEWs visit during pregnancy was weaker for antenatal care attendance [Adjusted Odds Ratio: 1.35(95% CI: 1.05, 1.72)] but positively and significantly associated with health facility delivery [Adjusted Odds Ratio 1.96(1.25,3.06)]. In general HEWs visit during pregnancy improved utilization of maternal health services. Health facility delivery is heavily affected by other factors. Meaningful improvement in skilled attendance at birth (health facility delivery) should include addressing other factors on top of visits by HEWs during pregnancy and specific target oriented interventions during visits by HEWs to support skilled attendance at birth.
Health education telecommunications experiment
NASA Technical Reports Server (NTRS)
Whalen, A. A.
1975-01-01
The Health/Education Telecommunications Experiment (HET) was conducted jointly by NASA and HEW on NASA's ATS-6 communications satellite. This experiment actually consisted of six experiments testing health and education applications of a communication spacecraft producing a broadcast of color television directly from space to over 120 low-cost receivers located in remote rural areas throughout the U.S. (including Alaska). The experiments were conducted over the period from 2 July 1974 to 20 May 1975 and operated on an almost daily basis. The overall telecommunications system to support these experiments consisted of many elements: The ATS-6 spacecraft; five different types of earth stations consisting of 120 video receive terminals, 51 telephony tranceivers and eight video originating terminals of three different types. Actual performance of the equipment as measured in the field was shown to equal or exceed predicted values.
32 CFR 644.483 - Notification of Department of HEW or successor agencies.
Code of Federal Regulations, 2012 CFR
2012-07-01
... improvements will be withheld from advertisement for bids for a period of 20 days from the date of the... health, including research. If within the 20-day period, notice is received of a potential need, the...
32 CFR 644.483 - Notification of Department of HEW or successor agencies.
Code of Federal Regulations, 2013 CFR
2013-07-01
... improvements will be withheld from advertisement for bids for a period of 20 days from the date of the... health, including research. If within the 20-day period, notice is received of a potential need, the...
32 CFR 644.483 - Notification of Department of HEW or successor agencies.
Code of Federal Regulations, 2014 CFR
2014-07-01
... improvements will be withheld from advertisement for bids for a period of 20 days from the date of the... health, including research. If within the 20-day period, notice is received of a potential need, the...
32 CFR 644.483 - Notification of Department of HEW or successor agencies.
Code of Federal Regulations, 2011 CFR
2011-07-01
... improvements will be withheld from advertisement for bids for a period of 20 days from the date of the... health, including research. If within the 20-day period, notice is received of a potential need, the...
A Cautious Green Light for Reproductive Studies.
ERIC Educational Resources Information Center
Randal, Judith
1979-01-01
The board that advises the Secretary of HEW on ethics has given a qualified approval for further review of federal funding for research on human embryos conceived in the laboratory. Issues and concerns that influenced the board's decision are addressed. (JMD)
Otto, Kate; Herbst, Christopher H.
2017-01-01
Background The provision of consistent and quality maternal and child health (MCH) services is a challenge for Ethiopia where most of the population lives in the rural setup. Health service delivery is constrained mainly by shortage of health professionals, meager resources, limited awareness among the society and bureaucratic procedures. Low health service utilization of antenatal care (ANC), delivery services, and postnatal care (PNC) are believed to contribute for high maternal and child mortality rates. Innovative approach like mHealth based technological intervention believed to alleviate such challenges in countries like ours. However, currently, there are few evidences that demonstrate the impact of mHealth technology applications on the level of service utilization. Therefore, the objective our study is to assess the role of mobile phone equipped with short message service (SMS) based data-exchange software linking community health workers to Health Centers in rural Ethiopia affect selected MCH outcomes. Methods A community-based randomized control trial (RCT) was conducted in three woredas of Guraghe zone (Ezha, partial &Abeshge full intervention, Sodo Control). Mobile phones equipped with FrontlineSMS based, locally developed application was distributed to all health extension workers (HEWs) to both intervention woredas who filled maternal, child and stock related forms and submitted to the central server which in turn sends reminder about the scheduled date of ANC visit, expected date of delivery, PNC, immunization schedule and vaccine and contraceptive stock status. Moreover, in Abeshge, the voluntary health workers (vCHW) and HEW supervisors in both intervention woreda were given a phone to facilitate communication with the HEW. No mobile was offered to the control woreda.Pre [2012] and post [2013] intervention community based survey on mothers who have under 5 and under 1 year old child was done to assess the effect of the mobile intervention on selected MCH process indicators. Structured and pretested questionnaire was used to collect data and SPSS v16 statistical software was used for analysis. Results Three thousand two hundred and forty mothers, 1,080 from each, were surveyed in the three woredas. The study revealed that the proportion of mothers receiving more than four ANC visits increased significantly in both intervention woredas. Besides, the rate of ANC delivered by HEWs improved in Ezha woreda (T1) (19.01% to 28.27%), proportions of deliveries attended by skilled health workers increased and home delivery decreased in all woredas; most pronounced increases in referrals from health post to health center by HEWs, reported in Ezha and Abeshge. The intervention also led to a significant reduction in stock-outs of preferred contraceptive products in Ezha (T1) from 16.96% to 8.24% but no change was observed in both contraceptive prevalence and immunization rates in the control and the other intervention woreda. Conclusions The study confirmed the positive contribution of SMS based mobile phone intervention in most of the selected MCH service indicators, like improvement in the percent of recommended number of ANC visit, percentage of delivery attended by health workers and facilitating the work processes of the health workers in rural Ethiopia. PMID:29184891
Atnafu, Asfaw; Otto, Kate; Herbst, Christopher H
2017-01-01
The provision of consistent and quality maternal and child health (MCH) services is a challenge for Ethiopia where most of the population lives in the rural setup. Health service delivery is constrained mainly by shortage of health professionals, meager resources, limited awareness among the society and bureaucratic procedures. Low health service utilization of antenatal care (ANC), delivery services, and postnatal care (PNC) are believed to contribute for high maternal and child mortality rates. Innovative approach like mHealth based technological intervention believed to alleviate such challenges in countries like ours. However, currently, there are few evidences that demonstrate the impact of mHealth technology applications on the level of service utilization. Therefore, the objective our study is to assess the role of mobile phone equipped with short message service (SMS) based data-exchange software linking community health workers to Health Centers in rural Ethiopia affect selected MCH outcomes. A community-based randomized control trial (RCT) was conducted in three woredas of Guraghe zone (Ezha, partial &Abeshge full intervention, Sodo Control). Mobile phones equipped with FrontlineSMS based, locally developed application was distributed to all health extension workers (HEWs) to both intervention woredas who filled maternal, child and stock related forms and submitted to the central server which in turn sends reminder about the scheduled date of ANC visit, expected date of delivery, PNC, immunization schedule and vaccine and contraceptive stock status. Moreover, in Abeshge, the voluntary health workers (vCHW) and HEW supervisors in both intervention woreda were given a phone to facilitate communication with the HEW. No mobile was offered to the control woreda.Pre [2012] and post [2013] intervention community based survey on mothers who have under 5 and under 1 year old child was done to assess the effect of the mobile intervention on selected MCH process indicators. Structured and pretested questionnaire was used to collect data and SPSS v16 statistical software was used for analysis. Three thousand two hundred and forty mothers, 1,080 from each, were surveyed in the three woredas. The study revealed that the proportion of mothers receiving more than four ANC visits increased significantly in both intervention woredas. Besides, the rate of ANC delivered by HEWs improved in Ezha woreda (T1) (19.01% to 28.27%), proportions of deliveries attended by skilled health workers increased and home delivery decreased in all woredas; most pronounced increases in referrals from health post to health center by HEWs, reported in Ezha and Abeshge. The intervention also led to a significant reduction in stock-outs of preferred contraceptive products in Ezha (T1) from 16.96% to 8.24% but no change was observed in both contraceptive prevalence and immunization rates in the control and the other intervention woreda. The study confirmed the positive contribution of SMS based mobile phone intervention in most of the selected MCH service indicators, like improvement in the percent of recommended number of ANC visit, percentage of delivery attended by health workers and facilitating the work processes of the health workers in rural Ethiopia.
Environmental Pollution, A Selective Bibliography.
ERIC Educational Resources Information Center
Clearinghouse for Federal Scientific and Technical Information, Springfield, VA.
This bibliography on environmental pollution is comprised primarily of reports of federally sponsored research by such departments and agencies as HEW, Interior, AEC, NASA, Defense, Transportation, and others. The reports were selected from Clearinghouse announcement journals during the period 1968 through April 1970. The bibliography contains…
2014-07-08
CAPE CANAVERAL, Fla. -- In the KSC Training Auditorium at NASA's Kennedy Space Center in Florida, Dr. Mary Frances Berry, on stage, addresses the audience gathered for a special event marking the 50th anniversary of the Civil Rights Act of 1964, supported by a sign-language interpreter. Berry served as the assistant secretary for education in the U.S. Department of Health, Education and Welfare HEW between 1977 and 1980. From 1980 to 2004, she was a member of the U.S. Commission on Civil Rights, serving as chair from 1993 to 2004. Among Berry's many honors are the NAACP's Roy Wilkins Award, the Rosa Parks Award of the Southern Christian Leadership Conference, and the Ebony Magazine Black Achievement Award. She is one of 75 women featured in the book "I Dream a World: Portraits of Black Women Who Changed America." Sienna College Research Institute and the Women's Hall of Fame also designated her one of "America's Women of the Century." The event was presented by Kennedy's Office of Diversity and Equal Opportunity. For more information about Kennedy Space Center, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Kim Shiflett
2014-07-08
CAPE CANAVERAL, Fla. -- In the KSC Training Auditorium at NASA's Kennedy Space Center in Florida, Dr. Mary Frances Berry relates her personal experiences in the fight for civil liberties to employees gathered for a special event marking the 50th anniversary of the Civil Rights Act of 1964. Berry served as the assistant secretary for education in the U.S. Department of Health, Education and Welfare HEW between 1977 and 1980. From 1980 to 2004, she was a member of the U.S. Commission on Civil Rights, serving as chair from 1993 to 2004. Among Berry's many honors are the NAACP's Roy Wilkins Award, the Rosa Parks Award of the Southern Christian Leadership Conference, and the Ebony Magazine Black Achievement Award. She is one of 75 women featured in the book "I Dream a World: Portraits of Black Women Who Changed America." Sienna College Research Institute and the Women's Hall of Fame also designated her one of "America's Women of the Century." The event was presented by Kennedy's Office of Diversity and Equal Opportunity. For more information about Kennedy Space Center, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Kim Shiflett
2014-07-08
CAPE CANAVERAL, Fla. -- In the KSC Training Auditorium at NASA's Kennedy Space Center in Florida, Dr. Mary Frances Berry relates her personal experiences in the fight for civil liberties to employees gathered for a special event marking the 50th anniversary of the Civil Rights Act of 1964. Berry served as the assistant secretary for education in the U.S. Department of Health, Education and Welfare HEW between 1977 and 1980. From 1980 to 2004, she was a member of the U.S. Commission on Civil Rights, serving as chair from 1993 to 2004. Among Berry's many honors are the NAACP's Roy Wilkins Award, the Rosa Parks Award of the Southern Christian Leadership Conference, and the Ebony Magazine Black Achievement Award. She is one of 75 women featured in the book "I Dream a World: Portraits of Black Women Who Changed America." Sienna College Research Institute and the Women's Hall of Fame also designated her one of "America's Women of the Century." The event was presented by Kennedy's Office of Diversity and Equal Opportunity. For more information about Kennedy Space Center, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Kim Shiflett
ATHENA: system studies and optics accommodation
NASA Astrophysics Data System (ADS)
Ayre, M.; Bavdaz, M.; Ferreira, I.; Wille, E.; Fransen, S.; Stefanescu, A.; Linder, M.
2016-07-01
ATHENA is currently in Phase A, with a view to adoption upon a successful Mission Adoption Review in 2019/2020. After a brief presentation of the reference spacecraft (SC) design, this paper will focus on the functional and environmental requirements, the thermo-mechanical design and the Assembly, Integration, Verification & Test (AIVT) considerations related to housing the Silicon Pore Optics (SPO) Mirror Modules (MM) in the very large Mirror Assembly Module (MAM). Initially functional requirements on the MM accommodation are presented, with the Effective Area and Half Energy Width (HEW) requirements leading to a MAM comprising (depending on final mirror size selected) between 700-1000 MMs, co-aligned with exquisite accuracy to provide a common focus. A preliminary HEW budget allocated across the main error-contributors is presented, and this is then used as a reference to derive subsequent requirements and engineering considerations, including: The procedures and technologies for MM-integration into the Mirror Structure (MS) to achieve the required alignment accuracies in a timely manner; stiffness requirements and handling scheme required to constrain deformation under gravity during x-ray testing; temperature control to constrain thermo-elastic deformation during flight; and the role of the Instrument Switching Mechanism (ISM) in constraining HEW and Effective Area errors. Next, we present the key environmental requirements of the MMs, and the need to minimise shock-loading of the MMs is stressed. Methods to achieve this Ø are presented, including: Selection of a large clamp-band launch vehicle interface (LV I/F); lengthening of the shock-path from the LV I/F to the MAM I/F; modal-tuning of the MAM to act as a low-pass filter during launch shock events; use of low-shock HDRMs for the MAM; and the possibility to deploy a passive vibration solution at the LV I/F to reduce loads.
Umbilical cord care in Ethiopia and implications for behavioral change: a qualitative study.
Amare, Yared
2014-04-18
Infections account for up to a half of neonatal deaths in low income countries. The umbilicus is a common source of infection in such settings. This qualitative study investigates practices and perspectives related to umbilical cord care in Ethiopia. In-depth interviews (IDI) were conducted in a district in each of the four most populous regions in the country: Oromia, Amhara, Tigray and Southern Nations, Nationalities and Peoples Region (SNNPR). In each district, one community was purposively selected; and in each study community, IDIs were conducted with 6 mothers, 4 grandmothers, 2 Traditional Birth Attendants and 2 Health Extension Workers (HEWs). The two main questions in the interview guide related to cord care were: How was the umbilical cord cut and tied? Was anything applied to the cord stump immediately after cutting/in the first 7 days? Why was it applied/not applied? The study elucidates local cord care practices and the rational for these practices. Concepts underlying cord tying practices were how to stem blood flow and facilitate delivery of the placenta. Substances were applied on the cord to moisturize it, facilitate its separation and promote healing. Locally recognized cord problems were delayed healing, bleeding or swelling. Few respondents reported familiarity with redness of the cord - a sign of infection. Grandmothers, TBAs and HEWs were influential regarding cord care. This study highlights local rationale for cord practices, concerns about cord related problems and recognition of signs of infection. Behavioral change messages aimed at improving cord care including cleansing with CHX should address these local perspectives. It is suggested that HEWs and health facility staff target mothers, grandmothers, TBAs and other community women with messages and counseling.
The X-Ray Optics for the High Angular Resolution Imager (HARI)
NASA Technical Reports Server (NTRS)
Weisskopf, M. C.
2010-01-01
This slide presentation shows the basic parameters of the x-ray optics, the housing,a graph of the effective area vs energy, another graph showing the angular off-set vs HEW, and a series of graphs showing the detector offsets and tilts,
Position Papers on Bilingual Bicultural Educational Manpower Development.
ERIC Educational Resources Information Center
Montal Educational Associates, San Fernando, CA.
Selected by the Division of Manpower Development and Training, U. S. Office of Education (HEW, Washington, D. C.), the Montal Educational Associates conducted a Symposium for Bilingual-Bicultural Educational Manpower Development. The Symposium's purpose was to bring together Spanish Speaking educational and manpower experts from throughout the…
Directions in Substance Abuse Counseling, 2000.
ERIC Educational Resources Information Center
Cohen, Adam W., Ed.
2000-01-01
This volume of six lessons provides expert information on a variety of issues in substance abuse counseling. The lessons, which may be applied toward continuing education credits, are: (1) "Ethics in Substance Abuse Rehabilitation" (Robert L. Hewes); (2) "Addressing the Needs of Clients with Traumatic Injury and Alcoholism"…
Women in Sports, Spring 1977. Sports Kit.
ERIC Educational Resources Information Center
Women's Equity Action League, Washington, DC.
Information concerning the Washington-based Women's Equity Action League (WEAL), its legislative recommendations, and internship program is presented. Excerpts from Title IX sections applying to sport and a memorandum from the Department of Health, Education, and Welfare (HEW) regarding the legal obligations of school officials are included, as…
Ritalin: Education's Fix-It Drug?
ERIC Educational Resources Information Center
Divoky, Diane
1989-01-01
Describes the case of Casey Jesson, a hyperactive child ordered by the state of Hew Hampshire to ingest Ritalin or forego a public education. Despite adverse side effects and the perils of drug dependency, there is greater parental and educator acceptance of Ritalin than ever before. Scientologists are sparking an anti-Ritalin campaign. Includes…
Federal Programs Supporting Lifelong Learning.
ERIC Educational Resources Information Center
Christoffel, Pam, Comp.
Approximately 275 Federal programs support some form of lifelong learning. While the majority of the lifelong learning programs are administered by the various agencies within HEW, a significant number of programs are run by such Federal agencies as the Department of Justice, the National Foundation on the Arts and Humanities, and the Smithsonian…
Parent Education: Bandwagon, Bastard, or Bonafide.
ERIC Educational Resources Information Center
Kerckhoff, Florence G.
The author emphasizes the importance of education for parenthood and recommends such education for both adolescents and adults. In recent years, parenthood education for teenagers has been emphasized at the national level by the Children's Bureau, Office of Child Development, HEW. However, this emphasis is declining and parent education is…
Administrative Action to End Discrimination Based on Handicap: HEW's Section 504 Regulation.
ERIC Educational Resources Information Center
Engebretson, Mark F.
1979-01-01
Examines the drafting of regulations under Section 504 of the Rehabilitation Act of 1973, which prohibits discrimination against handicapped persons by recipients of federal funds. Available from Harvard Legislative Research Bureau, Langdell Hall, Harvard Law School, Cambridge, MA 02138; single copy $4.00. (Author/IRT)
On Campus with Women. Number 20. June 1978.
ERIC Educational Resources Information Center
Association of American Colleges, Washington, DC. Project on the Status and Education of Women.
The contents of this newsletter concern affirmative action and employment, education of women, women's studies, Title IX; medicine, sports, and international news. The following news items are included: increased part-time careers in academe, the status of women faculty in academe, new decisions on sex discrimination, HEW investigations of major…
Code of Federal Regulations, 2011 CFR
2011-07-01
... Office simultaneously with notification to the District Engineer that the property has been determined surplus to Federal requirements. The District Engineer will furnish such notification directly to the... need or request for assignment is received, whichever occurs first. (4) The District Engineer shall not...
Program Information and Application Procedures, Fiscal Year 1977. The Comprehensive Program.
ERIC Educational Resources Information Center
Fund for the Improvement of Postsecondary Education (DHEW), Washington, DC.
The Fund for the Improvement of Postsecondary Education, a separate organizational unit within HEW, is a grant-making organization that covers the entire range of postsecondary education and that funds policy-oriented and feasibility studies directly related to reform, innovation, and improvement. Directions for improvement are outlined in this…
Thesaurus/Glossary System. User's Guide. Improved Systems for Managing the Control of Paperwork.
ERIC Educational Resources Information Center
Hurley, Jeanne S.; And Others
Intended primarily for the use of NCES (National Center for Education Statistics) staff, this document contains installation-specific information for the Thesaurus/Glossary computer system as installed at the HEW (Health, Education and Welfare) Data Management Center. The first of three sections provides an overview of system objectives,…
Code of Federal Regulations, 2010 CFR
2010-07-01
... Office simultaneously with notification to the District Engineer that the property has been determined surplus to Federal requirements. The District Engineer will furnish such notification directly to the... need or request for assignment is received, whichever occurs first. (4) The District Engineer shall not...
Education Act Extends Sex Discrimination and Minimum Wage Provisions. Legislative Series 2.
ERIC Educational Resources Information Center
Employment Standards Administration (DOL), Washington, DC. Women's Bureau.
This brief presents highlights from the recently enacted Education Amendments which include comprehensive higher education provisions, authorization for greatly increased funding, and limitations on court-ordered busing. The act also establishes within HEW a National Institute of Education, whose prime purpose is to find ways to make educational…
Program Evaluation at HEW: Research versus Reality. Part 2: Education.
ERIC Educational Resources Information Center
Abert, James G., Ed.
Intended for both the student and the practitioner of evaluation, this book describes the state of the practice of program evaluation. Its focus is mainly institutional. Results of evaluation studies are of secondary importance. An introductory chapter written by the editor discusses evaluation at the Office of Education from 1967 through 1973.…
Special Report on Dental Care for Handicapped People.
ERIC Educational Resources Information Center
Rehabilitation Services Administration (DHEW), Washington, DC.
The document presents a Department of Health, Education and Welfare (HEW) special report on dental care for the handicapped. The nature and extent of the problem of providing dental services to the handicapped population is examined. The handicapped population is defined and their oral health status reviewed. Factors contributing to the poor oral…
[Use of satellites for public health purposes in tropical areas].
Meynard, J B; Orlandi, E; Rogier, C; Sbai Idrissi, K; Deparis, X; Peyreffite, C; Lightburn, E; Malosse, D; Migliani, R; Spiegel, A; Boutin, J P
2003-01-01
The epidemiological hallmark of the new millennium has been the emergence or recrudescence of transmissible diseases with high epidemic potential. Disease tracking is becoming an increasingly global task requiring implementation of more and more sophisticated control strategies and facilities for sustainable development. A promising initiative involves the use of satellite technology to monitor and forecast the spread of disease. The Health Early Warning System (HEWS) was designed based on successful application of satellite data in food programs as well as in other areas (e.g. weather, farming and fishing). The HEWS integrates data from communications, remote-sensing and positioning satellites. The purpose of this review is to present the main studies containing satellite data on public health in tropical areas. Satellite data has allowed development of more reactive epidemiological tracking networks better suited to increasing population mobility, correlation of environmental factors (vegetation index, rainfall and ocean surface color) with human, animal and insect factors in epidemiological studies and assessment of the role of such factors in the development or reappearance of disease. Satellite technology holds great promise for more efficient management of public health problems in tropical areas.
2014-07-08
CAPE CANAVERAL, Fla. -- In the KSC Training Auditorium at NASA's Kennedy Space Center in Florida, Dr. Mary Frances Berry, center, accepts a framed poster announcing her appearance from Center Director Robert Cabana, left, who made the opening remarks, and Yves Lamothe, right, transition manager for the Ground Systems Development and Operations Program, the master of ceremonies. Berry served as the assistant secretary for education in the U.S. Department of Health, Education and Welfare HEW between 1977 and 1980. From 1980 to 2004, she was a member of the U.S. Commission on Civil Rights, serving as chair from 1993 to 2004. Among Berry's many honors are the NAACP's Roy Wilkins Award, the Rosa Parks Award of the Southern Christian Leadership Conference, and the Ebony Magazine Black Achievement Award. She is one of 75 women featured in the book "I Dream a World: Portraits of Black Women Who Changed America." Sienna College Research Institute and the Women's Hall of Fame also designated her one of "America's Women of the Century." The event was presented by Kennedy's Office of Diversity and Equal Opportunity. For more information about Kennedy Space Center, visit http://www.nasa.gov/kennedy. Photo credit: NASA/Kim Shiflett
Simulated wetland conservation-restoration effects on water quantity and quality at watershed scale.
Wang, Xixi; Shang, Shiyou; Qu, Zhongyi; Liu, Tingxi; Melesse, Assefa M; Yang, Wanhong
2010-07-01
Wetlands are one of the most important watershed microtopographic features that affect hydrologic processes (e.g., routing) and the fate and transport of constituents (e.g., sediment and nutrients). Efforts to conserve existing wetlands and/or to restore lost wetlands require that watershed-level effects of wetlands on water quantity and water quality be quantified. Because monitoring approaches are usually cost or logistics prohibitive at watershed scale, distributed watershed models such as the Soil and Water Assessment Tool (SWAT), enhanced by the hydrologic equivalent wetland (HEW) concept developed by Wang [Wang, X., Yang, W., Melesse, A.M., 2008. Using hydrologic equivalent wetland concept within SWAT to estimate streamflow in watersheds with numerous wetlands. Trans. ASABE 51 (1), 55-72.], can be a best resort. However, there is a serious lack of information about simulated effects using this kind of integrated modeling approach. The objective of this study was to use the HEW concept in SWAT to assess effects of wetland restoration within the Broughton's Creek watershed located in southwestern Manitoba, and of wetland conservation within the upper portion of the Otter Tail River watershed located in northwestern Minnesota. The results indicated that the HEW concept allows the nonlinear functional relations between watershed processes and wetland characteristics (e.g., size and morphology) to be accurately represented in the models. The loss of the first 10-20% of the wetlands in the Minnesota study area would drastically increase the peak discharge and loadings of sediment, total phosphorus (TP), and total nitrogen (TN). On the other hand, the justifiable reductions of the peak discharge and loadings of sediment, TP, and TN in the Manitoba study area may require that 50-80% of the lost wetlands be restored. Further, the comparison between the predicted restoration and conservation effects revealed that wetland conservation seems to deserve a higher priority while both wetland conservation and restoration may be equally important. Copyright 2010 Elsevier Ltd. All rights reserved.
An Exploratory Study of Women in the Health Professions Schools. Volume VII: Women in Podiatry.
ERIC Educational Resources Information Center
Urban and Rural Systems Associates, San Francisco, CA.
In an exploratory study conducted for the Women's Action Program of HEW, the aims were to identify and explore the barriers to success that women face as MODVOPPP (Medicine, Osteopathic medicine, Dentistry, Veterinary medicine, Optometry, Podiatry, Pharmacy, and Public health) school applicants and students, and to describe the discrimination…
An Exploratory Study of Women in the Health Professions Schools: Volume VIII: Women in Pharmacy.
ERIC Educational Resources Information Center
Urban and Rural Systems Associates, San Francisco, CA.
In an exploratory study conducted for the Women's Action Program of HEW, the aims were to identify and explore the barriers to success that women face as MODVOPPP (Medicine, Osteopathic medicine, Dentistry, Veterinary medicine, Optometry, Podiatry, Pharmacy, and Public health) school applicants and students and to describe the discrimination…
An Exploratory Study of Women in the Health Professions Schools. Volume VI: Women in Optometry.
ERIC Educational Resources Information Center
Urban and Rural Systems Associates, San Francisco, CA.
In an exploratory study conducted for the Women's Action Program of HEW, the aims were to identify and explore the barriers to success that women face as MODVOPPP (Medicine, Osteopathic medicine, Dentistry, Veterinary medicine, Optometry, Podiatry, Pharmacy, and Public health) school applicants and students and to describe the discrimination…
The Role of Gatekeepers in the Asbestos Awareness Campaign.
ERIC Educational Resources Information Center
Freimuth, Vicki S.; Van Nevel, J. Paul
The role of news media as gatekeepers controlling the flow of information that the public receives was explored during the 1978 Asbestos Awareness campaign conducted by the Department of Health, Education, and Welfare (HEW). In an effort to inform high risk workers and the general public about the health hazards associated with asbestos exposure,…
Initial Development of Criteria for Assessing Quality of Medical Care.
ERIC Educational Resources Information Center
Ironside, Roderick A.
In 1969, the Medical School of the University of Puerto Rico (UPR) received a grant from the National Center for Health Services Research and Development (Public Health Service, HEW) to plan and conduct--as a demonstration project--a special retraining program for physicians who had failed to approve the licensure examinations of the Puerto Rico…
ERIC Educational Resources Information Center
Mazzarella, Jo Ann
Title IX of the Education Amendments of 1972 and the HEW implementing regulations cover two major areas: sex discrimination in school courses, athletics, extracurricular activities, employment, and counseling, and sex descrimination in hiring, promotions, and benefits for school personnel. The author of this review examines the progress (and lack…
U. S. ground troops in South Vietnam were in areas sprayed with herbicide orange
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1979-11-16
Between 1966 and 1969 a large number of U.S. ground troops in Vietnam were in areas sprayed with herbicide orange both during and shortly after spraying. DOD took few precautions to prevent exposure because at that time it did not consider the herbicide to be toxic or dangerous to humans. Marines assigned to units in sprayed areas can be identified, but Army personnel cannot because Army records are incomplete. Troops' actual exposure or the degree of exposure to the herbicide cannot be documented from available records. Also, the long-term efects of exposure remain largely unknown. The Congress should direct DOD,more » VA, HEW, or the Environmental Protection Agency to determine whether a study is needed of the health effects of herbicide orange on ground troops discussed in this report. GAO issued this report at the request of Senator Charles Percy, Ranking Minority Member of the Permanent Subcommittee on Investigations, Senate Committee on Governmental Affairs.« less
ERIC Educational Resources Information Center
Office of Education (DHEW), Washington, DC. Office of Environmental Education.
In December 1977, the Office of Environmental Education (OEE) brought its fiscal year '77 grant recipients together in Boulder, Colorado, for a technical assistance consultation. The technical assistance responsibilities of OEE are mandated by the Environmental Education Act. Until this consultation, OEE had been giving its technical assistance on…
Summary and Recommendations: Conference on Pacific/Asian American Families and HEW-Related Issues.
ERIC Educational Resources Information Center
J W K International Corp., Annandale, VA.
The socioeconomic needs of Pacific and Asian American (PAA) families and Department of Health, Education, and Welfare programs having the most impact on the lives of PAAs are analyzed in this conference report. An overall outline of the conference proceedings, as well as reprints of all charts and papers presented, are included. The findings of…
ERIC Educational Resources Information Center
Ghadirian, Hajar; Ayub, Ahmad Fauzi Mohd; Bakar, Kamariah Binti Abu; Hassanzadeh, Maryam
2016-01-01
This study presents a case study of asynchronous online discussions' (AOD) growth patterns in an undergraduate blended course to address the gap in our current understanding of how threads are developed in peer-moderated AODs. Building on a taxonomy of thread pattern proposed by Chan, Hew and Cheung (2009), growth patterns of thirty-six forums…
Academic Writing in Context: Implications and Applications. Papers in Honour of Tony Dudley-Evans.
ERIC Educational Resources Information Center
Hewings, Martin, Ed.
The papers in this volume were collected to honor T. Dudley-Evans on his retirement from the University of Birmingham. They explore a number of themes of current interest to those engaged in English language teaching and academic writing. The papers are: (1) Introduction (Martin Hewings); (2) Distance and Refined Selves: Educational Tensions in…
ERIC Educational Resources Information Center
Larson, Meredith A.; And Others
This two part study was designed to determine whether working relationships can be expanded between the Office for Civil Rights (OCR) and various State agencies with similar missions. First, a survey of State laws and enforcement mechanisms identifies those States with current laws or policies similar to those that OCR administers. Results…
ERIC Educational Resources Information Center
Crump, Carol B., Ed.
This document contains abstracts of papers from a workshop resulting from events stemming from the Office of Education report, A Look at Women in Education: Issues and Answers for HEW. This report charged that a particular career interest inventory was sex-biased, but no operational definition of sex bias was given, the issues involved were not…
ERIC Educational Resources Information Center
Truckenmiller, James L.
The accurate prediction of violence has been in the spotlight of critical concern in recent years. To investigate the relative predictive power of peer pressure, youth perceived negative labeling, youth perceived access to educational and occupational roles, social alienation, self-esteem, sex, and age with regard to gang fight participation…
ERIC Educational Resources Information Center
Herman, Alexis M.
There is a great need to examine factors limiting educational opportunities of women, especially minority and low income women. Thus, it is important to identify funding sources for research and development programs which enhance women's educational equity. Possible funding sources include the Department of Labor and other federal programs. In the…
ERIC Educational Resources Information Center
Wigginton, Eliot, Ed.
Planting by the signs of the moon, well digging, hewing logs, wood carving, knife making, bird trapping, and horsetrading are but a few of the aspects of Appalachian culture explored in "Foxfire 4." Like its predecessors, the volume was compiled by high school students at Rabun Gap-Nacoochee School. Information on the cultural heritage…
ERIC Educational Resources Information Center
Vasquez Associates Ltd., Milwaukee, WI.
Nine Street Projects designed for the Spanish speaking and funded by Region V of the Department of Health, Education and Welfare (HEW) are examined here. They were: the El Hogar del Nino Day Care Center, Spanish-American Day Care Center, United Migrant Opportunity Services' Bilingual/Bicultural Early Childhood Center, Youth Services at El Centro…
Electric Field Distortion in Electro-Optical Devices Subjected to Ionizing Radiation.
1983-12-26
applies- ties of scientif ic advances to nam military spae system . Versatilty and flaxibility hews beon developed to a high degree by the lehoratory...personel In deeling with the many problems encountered ina the nation’s rapidly dsvelopnas space system . 1expertise In the latest scientific developments is...desiga, distributed architectures for spacoerne m o putars, fault-tolerant c.speter system , artificia intelligence. end microelectronics applications
ERIC Educational Resources Information Center
Comptroller General of the U.S., Washington, DC.
Presented is a report on the current status of implementation of the Presidential goal (made in 1971) to reduce by half the incidence of mental retardation by the end of this century. Major conclusions are as follows: no major agency of the Department of Health, Education, and Welfare (HEW) has been made responsible for seeing that the goal is put…
ERIC Educational Resources Information Center
Vasquez Associates Ltd., Milwaukee, WI.
The main portion of this study is devoted to the determination of needs for health, education and social welfare services of the Spanish speaking in Chicago, and to draw inferences about the degree to which Department of Health, Education and Welfare (HEW) funds and services in Chicago are reaching this specific minority and the extent to which…
Crowd Sourcing Data Collection through Amazon Mechanical Turk
2013-09-01
The first recognition study consisted of a Panel Study using a simple detection protocol, in which participants were presented with vignettes and, for...variability than the crowdsourcing data set, hewing more closely to the year 1 verbs of interest and simple description grammar . The DT:PS data were...Study RT: PS Recognition Task: Panel Study RT: RT Recognition Task: Round Table S3 Amazon Simple Storage Service SVPA Single Verb Present /Absent
History of the Army Nuclear Test Personnel Review (ANTPR).
1987-09-01
weM S HISTORY OF THE AMR NUCLEAR TEST PERSONNEL REVIEW 1/1 CUITPR)(U) ARMY AMP JOINT SERVICES ENVIRONENTAL SUPPORT GROUP IMSHINSTON DC SEP 6...participants. 7 Apri 1978 VA issued Circular 10-78-69 authorizing physical examinations for nuclear test participants. 9fMay 1978 The White House directed HEW...testified at a hearing held by the Subcommittee of the House Committee on Government Operations. They discussed DOD re- search to identify participants in
Legislation to regulate medical devices.
Harris, M
1975-01-01
The history of medical device regulation began with the need to rid the marketplace of bogus inventions which were either harmful in themselves or harmful because they delayed meaningful treatment of illness. Since World War II, sophistication in medical technology and development of electronic and other types of medical devices has created a new need for regulation of safety and performance of devices used to cure and mitigate disease in man. The 1938 amendments to the Food, Drug, and Cosmetic Act gave FDA authority over labeling and advertising of devices, enforceable only after devices were marketed. In 1969 a study by an HEW commission documented the need for further legislation. The commission recommended three categories of medical devices: those requiring premarket clearance or scientific review, those for which standards could be established to protect the public, and those which are generally recognized as safe and for which nor standards would be necessary. In 1974 the Senate unanimously approved Senator Kennedy's "Medical Device Amendments of 1973" legislation which fulfills the recommendations of the HEW commission report. The House of Representatives failed to pass their version of the legislation in the 93rd Congress. Senator Kennedy re-introduced the bill in the 94th Congress and it passed the Senate in April 1975. Representative Rogers re-introduced an amended bill. The bill is expected to become law in 1975.
1983-01-01
potentially hazardous food requiring refrigeration should be cooled rapidly to an internal temperature of 450F or below so that the cooling period...does not exceed four hours; (c) potentially hazardous food to be served chilled should be kept at an internal temperature of 450F or below during...display and service (HEW, 1978). Potentially hazardous food - any food that consists in whole or in part of milk or milk products, eggs, meat, poultry
Space age health care delivery
NASA Technical Reports Server (NTRS)
Jones, W. L.
1977-01-01
Space age health care delivery is being delivered to both NASA astronauts and employees with primary emphasis on preventive medicine. The program relies heavily on comprehensive health physical exams, health education, screening programs and physical fitness programs. Medical data from the program is stored in a computer bank so epidemiological significance can be established and better procedures can be obtained. Besides health care delivery to the NASA population, NASA is working with HEW on a telemedicine project STARPAHC, applying space technology to provide health care delivery to remotely located populations.
Design and development of the SIMBOL-X hard x-ray optics
NASA Astrophysics Data System (ADS)
Pareschi, G.; Attinà, P.; Basso, S.; Borghi, G.; Burkert, W.; Buzzi, R.; Citterio, O.; Civitani, M.; Conconi, P.; Cotroneo, V.; Cusumano, G.; Dell'Orto, E.; Freyberg, M.; Hartner, G. D.; Gorenstein, P.; Mattaini, E.; Mazzoleni, F.; Parodi, G.; Romaine, S.; Spiga, D.; Tagliaferri, G.; Valtolina, R.; Valsecchi, G.; Vernani, D.
2008-07-01
The SIMBOL-X formation-flight X-ray mission will be operated by ASI and CNES in 2014, with a large participation of the French and Italian high energy astrophysics scientific community. Also German and US Institutions are contributing in the implementation of the scientific payload. Thanks to the formation-flight architecture, it will be possible to operate a long (20 m) focal length grazing incidence mirror module, formed by 100 confocal multilayer-coated Wolter I shells. This system will allow us to focus X-rays over a very broad energy band, from 0.5 keV up to 80 keV and beyond, with more than two orders of magnitude improvement in angular resolution (20 arcsec HEW) and sensitivity (0.5 µCrab on axis @30 keV) compared to non focusing detectors used so far. The X-ray mirrors will be realized by Ni electroforming replication, already successfully used for BeppoSAX, XMM-Newton, and JET-X/SWIFT; the thickness trend will be about two times less than for XMM, in order to save mass. Multilayer reflecting coatings will be implemented, in order to improve the reflectivity beyond 10 keV and to increase the field of view 812 arcmin at 30 keV). In this paper, the SIMBOL-X optics design, technology and implementation challenges will be discussed; it will be also reported on recent results obtained in the context of the SIMBOL-X optics development activities.
2009-02-19
Stennis Space Center leaders and guests visit with Mississippi Senate members in chambers during NASA Day at the Capitol events in Jackson on Feb. 19. Standing at the Senate podium (rear) is Mississippi Lt. Gov. Phil Bryant. Standing at the lectern below are (l to r): Sen. David Baria, D-Bay St. Louis; Partners for Stennis Chair Clay Wagner; NASA Shared Services Center Director Rick Arbuthnot; astronaut Rex Walheim; Stennis Space Center Director Gene Goldman; President Pro Tempore Billy Hewes, R-Gulfport; Sen. Ezell Lee, D-Picayune; and Sen. Tommy Gollott, R-Biloxi.
Molecular and Metallic Hydrogen
1977-05-01
ANO ADDRESS IL PR09RAM 91.ME XT. CH ~1 The Rand Corporation 1700 Main Street Santa Monica, Ca. .90406 It. CONTROLLING OFFICE NAME AND ADDRE~SS Defense...VOLUME DATA OF STEWART FOR MOLECULAR HYDROGEN P V/V P V/V (bar) o(_ark . 0 1000 3923 0.632 196.1 0.928 5884 0.583 392.2 0.883 7845 0.549 588.4 0.847...will not a *ieve metailic-like densities despite possib* M tbar pressures because, as the result of shock hew, tng, m.’ ch of the pressure is thermal and
Two-way time transfers between NRC/NBS and NRC/USNO via the Hermes (CTS) satellite
NASA Technical Reports Server (NTRS)
Costain, C. C.; Daams, H.; Boulanger, J. S.; Hanson, D. W.; Klepczynski, W. J.
1978-01-01
At each station the differences were measured between the local UTC seconds pulse and the remote UTC pulse received by satellite. The difference between the readings, if station delays are assumed to be symmetrical, is two times the difference between the clocks at the two ground station sites. Over a 20-minute period, the precision over the satellite is better than 1 ns. The time transfer from NRC to the CRC satellite terminal near Ottawa and from NBS to the Denver HEW terminal was examined.
Wave Propagation and Dynamics of Lattice Structures.
1984-05-01
Progress in Solid Mechanics, North Holand Publishing Company, Amsterdam, 1960. [7) Y. K. Linn, and T. J. McDaniel, ’n)amics of Beam Type Periodic...deformation. -99- APPENDIX F FREQUENCY RESPONSE AND IMPULSE RESPONSE FUNCTIONS FOR LONGITUDINAL VIBRATION IN AN ELASTIC ROD Figure F1 shows the elastic rod to b...6 (F38) Rearranging eqn. (F38), .HE(w) = e’ 4e~3 ~e e 2 e1" +e " 6 e r (F39) Mlultiplying eqn. ( F1 =39) by 6Ŕ 6- and aragn te - . e 6 -e _ aix
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Committee on Labor and Public Welfare.
This volume of hearings before the Sub-committee on Education of the Committee on Labor and Public Welfare, United States Senate, is organized into three sections, the contents of which are as follows: Section One comprises the testimony of four witnesses before the Committee; Director Office for Civil Rights, Department of Health, Education and…
NASA Astrophysics Data System (ADS)
Tanaka, I.; Minezaki, Y.; Harada, K.; Niimura, N.
An elastically bent silicon (EBSi) as a monochromator has been optimized for neutron diffractometers of biocrystallography. It was found that several stacked thin Si plates were easier to be bent much for the near focusing point and they increased neutron reflectivity by aligning the plates. Currently, an EBSi(1 1 1) monochromator system was equipped at a diffractometer (BIX-I). It took 50 days to collect about 12 000 reflections of hen-egg-white lysozyme. The minimum d-spacing was 2.1 Å.
Simulation and modeling of silicon pore optics for the ATHENA x-ray telescope
NASA Astrophysics Data System (ADS)
Spiga, D.; Christensen, F. E.; Bavdaz, M.; Civitani, M. M.; Conconi, P.; Della Monica Ferreira, D.; Knudsen, E. B.; Massahi, S.; Pareschi, G.; Salmaso, B.; Shortt, B.; Tayabaly, K.; Westergaard, N. J.; Wille, E.
2016-07-01
The ATHENA X-ray observatory is a large-class ESA approved mission, with launch scheduled in 2028. The technology of silicon pore optics (SPO) was selected as baseline to assemble ATHENA's optic with more than 1000 mirror modules, obtained by stacking wedged and ribbed silicon wafer plates onto silicon mandrels to form the Wolter-I configuration. Even if the current baseline design fulfills the required effective area of 2 m2 at 1 keV on-axis, alternative design solutions, e.g., privileging the field of view or the off-axis angular resolution, are also possible. Moreover, the stringent requirement of a 5 arcsec HEW angular resolution at 1 keV entails very small profile errors and excellent surface smoothness, as well as a precise alignment of the 1000 mirror modules to avoid imaging degradation and effective area loss. Finally, the stray light issue has to be kept under control. In this paper we show the preliminary results of simulations of optical systems based on SPO for the ATHENA X-ray telescope, from pore to telescope level, carried out at INAF/OAB and DTU Space under ESA contract. We show ray-tracing results, including assessment of the misalignments of mirror modules and the impact of stray light. We also deal with a detailed description of diffractive effects expected in an SPO module from UV light, where the aperture diffraction prevails, to X-rays where the surface diffraction plays a major role. Finally, we analyze the results of X-ray tests performed at the BESSY synchrotron, we compare them with surface finishing measurements, and we estimate the expected HEW degradation caused by the X-ray scattering.
Hambisa, Mitiku Teshome; Debela, Tessema; Dessie, Yadeta; Gobena, Tesfaye
2018-01-10
Many countries in sub-Saharan Africa, including Ethiopia, are focusing on the distribution of Long Lasting Insecticidal Nets (LLINs) to combat malaria. However, utilization of the LLIN is low when compared with LLIN possession because of various factors. This study was conducted to measure the actual LLIN usage and identify factors associated with its utilization in Limmu Seka District, South West Ethiopia. A community based cross-sectional survey was conducted among 830 households from December 25, 2011 to February 29, 2012. A total of 830 households were selected by stratified systematic sampling and surveyed. Ninety percent of those surveyed owned LLINs and 68.3% reported that someone had slept under the net on the night prior to the survey. The factors associated with LLIN usage were knowledge of the mode of malaria transmission (AOR; 0.086, 95% CI 0.03, 0.24), the preferred conical shapes of the LLIN (AOR; 1.6, 95% CI 1.31, 4.1), receiving information about their use from Health Extension Workers (HEWs) (AOR; 2.4, 95% CI 1.5, 3.9), hearing media campaigns (AOR; 3.2 95% CI 3.5, 9.2), education at a health facility (AOR; 2 95% CI 1.5, 3.9) or having a family size of three or less (AOR; 2.1, 95% CI 1.3, 3.5). Although ownership of Long Lasting Insecticidal Nets was high at 90%, the actual usage of LLIN was low, and not all family members were protected. Promoting the usage of LLINs utilization by those at most risk, especially the conical shaped ones, through intensified health education using HEWs and mass media campaigns at all health facilities, schools and communities will improve LLIN utilization.
Shaw, Bryan; Amouzou, Agbessi; Miller, Nathan P; Bryce, Jennifer; Surkan, Pamela J
2017-03-09
Ethiopia has experienced rapid improvements in its healthcare infrastructure, such as through the recent scale up of integrated community case management (iCCM) delivered by community-based health extension workers (HEWs) targeting children under the age of five. Despite notable improvements in child outcomes, the use of HEWs delivering iCCM remains very low. The aim of our study was to explain this phenomenon by examining care-seeking practices and treatment for sick children in two rural districts in the Oromia Region of Ethiopia. Using qualitative methods, we explored perceptions of child illness, influences on decision-making processes occurring over the course of a child's illness and caregiver perceptions of available community-based sources of child illness care. Sixteen focus group discussions (FGDs) and 40 in-depth interviews (IDIs) were held with mothers of children under age five. For additional perspective, 16 IDIs were conducted fathers and 22 IDIs with health extension workers and community health volunteers. Caregivers often described the act of care-seeking for a sick child as a time of considerable uncertainty. In particular, mothers of sick children described the cultural, social and community-based resources available to minimize this uncertainty as well as constraints and strategies for accessing these resources in order to receive treatment for a sick child. The level of trust and familiarity were the most common dynamics noted as influencing care-seeking strategies; trust in biomedical and government providers was often low. Overall, our research highlights the multiple and dynamic influences on care-seeking for sick children in rural Ethiopia. An understanding of these influences is critical for the success of existing and future health interventions and continued improvement of child health in Ethiopia.
Science requirements and optimization of the silicon pore optics design for the Athena mirror
NASA Astrophysics Data System (ADS)
Willingale, R.; Pareschi, G.; Christensen, F.; den Herder, J.-W.; Ferreira, D.; Jakobsen, A.; Ackermann, M.; Collon, M.; Bavdaz, M.
2014-07-01
The science requirements for the Athena X-ray mirror are to provide a collecting area of 2 m2 at 1 keV, an angular resolution of ~5 arc seconds half energy eidth (HEW) and a field of view of diameter 40-50 arc minutes. This combination of area and angular resolution over a wide field are possible because of unique features of the Silicon pore optics (SPO) technology used. Here we describe the optimization and modifications of the SPO technology required to achieve the Athena mirror specification and demonstrate how the optical design of the mirror system impacts on the scientific performance of Athena.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Koizumi, H.; Uda, S.; Fujiwara, K.
X-ray diffraction rocking-curve measurements were performed on tetragonal hen egg white (HEW) lysozyme crystals grown with and without the application of an external alternating current (AC) electric field. The crystal quality was assessed by the full width at half maximum (FWHM) value for each rocking curve. For two-dimensional maps of the FWHMs measured on the 440 and the 12 12 0 reflection, the crystal homogeneity was improved under application of an external electric field at 1 MHz, compared with that without. In particular, the significant improvement of the crystal homogeneity was observed for the 12 12 0 reflection.
Epistemic beliefs' role in promoting misperceptions and conspiracist ideation.
Garrett, R Kelly; Weeks, Brian E
2017-01-01
Widespread misperceptions undermine citizens' decision-making ability. Conclusions based on falsehoods and conspiracy theories are by definition flawed. This article demonstrates that individuals' epistemic beliefs-beliefs about the nature of knowledge and how one comes to know-have important implications for perception accuracy. The present study uses a series of large, nationally representative surveys of the U.S. population to produce valid and reliable measures of three aspects of epistemic beliefs: reliance on intuition for factual beliefs (Faith in Intuition for facts), importance of consistency between empirical evidence and beliefs (Need for evidence), and conviction that "facts" are politically constructed (Truth is political). Analyses confirm that these factors complement established predictors of misperception, substantively increasing our ability to explain both individuals' propensity to engage in conspiracist ideation, and their willingness to embrace falsehoods about high-profile scientific and political issues. Individuals who view reality as a political construct are significantly more likely to embrace falsehoods, whereas those who believe that their conclusions must hew to available evidence tend to hold more accurate beliefs. Confidence in the ability to intuitively recognize truth is a uniquely important predictor of conspiracist ideation. Results suggest that efforts to counter misperceptions may be helped by promoting epistemic beliefs emphasizing the importance of evidence, cautious use of feelings, and trust that rigorous assessment by knowledgeable specialists is an effective guard against political manipulation.
Epistemic beliefs’ role in promoting misperceptions and conspiracist ideation
Weeks, Brian E.
2017-01-01
Widespread misperceptions undermine citizens’ decision-making ability. Conclusions based on falsehoods and conspiracy theories are by definition flawed. This article demonstrates that individuals’ epistemic beliefs–beliefs about the nature of knowledge and how one comes to know–have important implications for perception accuracy. The present study uses a series of large, nationally representative surveys of the U.S. population to produce valid and reliable measures of three aspects of epistemic beliefs: reliance on intuition for factual beliefs (Faith in Intuition for facts), importance of consistency between empirical evidence and beliefs (Need for evidence), and conviction that “facts” are politically constructed (Truth is political). Analyses confirm that these factors complement established predictors of misperception, substantively increasing our ability to explain both individuals’ propensity to engage in conspiracist ideation, and their willingness to embrace falsehoods about high-profile scientific and political issues. Individuals who view reality as a political construct are significantly more likely to embrace falsehoods, whereas those who believe that their conclusions must hew to available evidence tend to hold more accurate beliefs. Confidence in the ability to intuitively recognize truth is a uniquely important predictor of conspiracist ideation. Results suggest that efforts to counter misperceptions may be helped by promoting epistemic beliefs emphasizing the importance of evidence, cautious use of feelings, and trust that rigorous assessment by knowledgeable specialists is an effective guard against political manipulation. PMID:28922387
Beam, Nancy K; Bekele Dadi, Gezehegn; Rankin, Sally H; Weiss, Sandra; Cooper, Bruce; Thompson, Lisa M
2018-01-01
Objectives Despite global efforts to increase facility-based delivery (FBD), 90% of women in rural Ethiopia deliver at home without a skilled birth attendant. Men have an important role in increasing FBD due to their decision-making power, but this is largely unexplored. This study aimed to determine the FBD care attributes preferred by women and men, and whether poverty or household decision-making are associated with choice to deliver in a facility. Setting and participants We conducted a cross-sectional discrete choice experiment in 109 randomly selected households in rural Ethiopia in September–October 2015. We interviewed women who were pregnant or who had a child <2 years old and their male partners. Results Both women and men preferred health facilities where medications and supplies were available (OR=3.08; 95% CI 2.03 to 4.67 and OR=2.68; 95% CI 1.79 to 4.02, respectively), a support person was allowed in the delivery room (OR=1.69; 95% CI 1.37 to 2.07 and OR=1.74; 95% CI 1.42 to 2.14, respectively) and delivery cost was low (OR=1.15 95% CI 1.12 to 1.18 and OR=1.14; 95% CI 1.11 to 1.17, respectively). Women valued free ambulance service (OR=1.37; 95% CI 1.09 to 1.70), while men favoured nearby facilities (OR=1.09; 95% CI 1.06 to 1.13) with friendly providers (OR=1.30; 95% CI 1.03 to 1.64). Provider preferences were complex. Neither women nor men preferred female doctors to health extension workers (HEW) (OR=0.92; 95% CI 0.59 to 1.42 and OR=0.74; 95% CI 0.47 to 1.14, respectively), male doctors to HEW (OR=1.33; 95% CI 0.89 to 1.99 and OR=0.75; 95% CI 0.50 to 1.12, respectively) or female over male nurses (OR=0.68; 95% CI 0.94 to 1.71 and OR=1.03; 95% CI 0.77 to 2.94, respectively). While both women and men preferred male nurses to HEW (OR=1.86; 95% CI 1.23 to 2.80 and OR=1.95; 95% CI 1.30 to 2.95, respectively), men (OR=1.89; 95% CI 1.29 to 2.78), but not women (OR=1.47; 95% CI 1.00 to 2.13) preferred HEW to female nurses. Both women and men preferred female doctors to male nurses (OR=1.71; 95% CI 1.27 to 2.29 and OR=1.44; 95% CI 1.07 to 1.92, respectively), male doctors to female nurses (OR=1.95; 95% CI 1.44 to 2.62 and OR=1.41; 95% CI 1.05 to 1.90, respectively) and male doctors to male nurses (OR=2.47; 95% CI 1.84 to 3.32 and OR=1.46; 95% CI 1.09 to 1.95, respectively), while only women preferred male doctors to female doctors (OR=1.45; 95% CI 1.09 to 1.93 and OR=1.01; 95% CI 0.76 to 1.35, respectively) and only men preferred female nurses to female doctors (OR=1.34; 95% CI 0.98 to 1.84 and OR=1.39; 95% CI 1.02 to 1.89, respectively). Men were disproportionately involved in making household decisions (X2 (1, n=216)=72.18, p<0.001), including decisions to seek healthcare (X2 (1, n=216)=55.39, p<0.001), yet men were often unaware of their partners’ prenatal care attendance (X2 (1, n=215)=82.59, p<0.001). Conclusion Women’s and men’s preferences may influence delivery service choices. Considering these choices is one way the Ethiopian government and health facilities may encourage FBD in rural areas. PMID:29615441
Early Homo and the role of the genus in paleoanthropology.
Villmoare, Brian
2018-01-01
The history of the discovery of early fossils attributed to the genus Homo has been contentious, with scholars disagreeing over the generic assignment of fossils proposed as members of our genus. In this manuscript I review the history of discovery and debate over early Homo and evaluate the various taxonomic hypotheses for the genus. To get a sense of how hominin taxonomy compares to taxonomic practice outside paleoanthropology, I compare the diversity of Homo to genera in other vertebrate clades. Finally, I propose a taxonomic model that hews closely to current models for hominin phylogeny and is consistent with taxonomic practice across evolutionary biology. © 2018 American Association of Physical Anthropologists.
NASA Technical Reports Server (NTRS)
Finley, D.; Malina, R. F.; Bowyer, S.
1985-01-01
The four flight Wolter-Schwarzschild mirrors currently under fabrication for the Extreme Ultraviolet Explorer (EUVE) satellite are described. The principal figuring operation of these grazing incidence metal mirrors (gold over nickel on an aluminum substrate) is carried out by diamond turning at the Lawrence Livermore National Laboratories. Turning has been accomplished and optical testing results analyzed for three of the mirrors. As-turned values of 1.7 arc sec full width at half maximum (FWHM) and half energy width (HEW) of 5 arc seconds in the visible have been achieved. These results illustrate the great potential of precision fabrication technology for the production of large grazing incidence optics.
The Astrophysical r-Process 50 Years after B{sup 2}FH
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kratz, K.-L.; Pfeiffer, B.; Farouqi, K.
Since the historical papers by Burbidge et al. and Cameron 50 years ago, it is generally accepted that half of the chemical elements above Fe are formed in explosive stellar scenarios by a rapid neutron-capture process (the classical ''r-process''). Already from their essential ideas, it became clear that a correct modelling of this nucleosynthesis process requires both, the knowledge of various nuclear properties very far from stability and a detailed description of the astrophysical environments. However, it took about three decades, until in 1986 the first experimental nuclear-physics data on the neutron-magic r-isotopes {sup 80}Zn and {sup 130}Cd could bemore » obtained, which act as key ''waiting points'' in the respective A{approx_equal}80 and 130 peaks of the Solar-System (SS) r-abundances (N{sub r,{center_dot}}). Since then, using steadily improved nuclear data, we have optimized our r-process calculations to reproduce the present observables of the isotopic N{sub r,{center_dot}} ''residuals'', as well as the more recent elemental abundances in ultra-metal-poor, r-process-enriched halo stars. Concerning the latter observations, we support the basic idea about two different types of r-processes. Based on our many years' experience with the site-independent ''waiting-point approach'', we recently have extended our studies to fully dynamical network calculations for the most likely astrophysical r-process scenario, i.e. the high-entropy wind (HEW) of core-collapse type II supernovae (SN II). Again, an excellent reproduction of all observables for the ''main'' r-process has been achieved. However, a major difference is the nucleosynthesis origin of the lighter heavy elements in the 29{<=}Z{<=}45 mass region. Here, the HEW model predicts-instead of a ''weak'' neutron-capture r-process component-a primary rapid charged-particle process. This may explain the recent observations of a non-correlation of these elements with the heavier ''main'' r-process elements.« less
Little, Alex; Medhanyie, Araya; Yebyo, Henock; Spigt, Mark; Dinant, Geert-Jan; Blanco, Roman
2013-01-01
Background Mobile health applications are complex interventions that essentially require changes to the behavior of health care professionals who will use them and changes to systems or processes in delivery of care. Our aim has been to meet the technical needs of Health Extension Workers (HEWs) and midwives for maternal health using appropriate mobile technologies tools. Methods We have developed and evaluated a set of appropriate smartphone health applications using open source components, including a local language adapted data collection tool, health worker and manager user-friendly dashboard analytics and maternal-newborn protocols. This is an eighteen month follow-up of an ongoing observational research study in the northern of Ethiopia involving two districts, twenty HEWs, and twelve midwives. Results Most health workers rapidly learned how to use and became comfortable with the touch screen devices so only limited technical support was needed. Unrestricted use of smartphones generated a strong sense of ownership and empowerment among the health workers. Ownership of the phones was a strong motivator for the health workers, who recognised the value and usefulness of the devices, so took care to look after them. A low level of smartphones breakage (8.3%,3 from 36) and loss (2.7%) were reported. Each health worker made an average of 160 mins of voice calls and downloaded 27Mb of data per month, however, we found very low usage of short message service (less than 3 per month). Conclusions Although it is too early to show a direct link between mobile technologies and health outcomes, mobile technologies allow health managers to more quickly and reliably have access to data which can help identify where there issues in the service delivery. Achieving a strong sense of ownership and empowerment among health workers is a prerequisite for a successful introduction of any mobile health program. PMID:24204872
NASA Astrophysics Data System (ADS)
Brigandì, Giuseppina; Tito Aronica, Giuseppe; Bonaccorso, Brunella; Gueli, Roberto; Basile, Giuseppe
2017-09-01
The main focus of the paper is to present a flood and landslide early warning system, named HEWS (Hydrohazards Early Warning System), specifically developed for the Civil Protection Department of Sicily, based on the combined use of rainfall thresholds, soil moisture modelling and quantitative precipitation forecast (QPF). The warning system is referred to 9 different Alert Zones
in which Sicily has been divided into and based on a threshold system of three different increasing critical levels: ordinary, moderate and high. In this system, for early flood warning, a Soil Moisture Accounting (SMA) model provides daily soil moisture conditions, which allow to select a specific set of three rainfall thresholds, one for each critical level considered, to be used for issue the alert bulletin. Wetness indexes, representative of the soil moisture conditions of a catchment, are calculated using a simple, spatially-lumped rainfall-streamflow model, based on the SCS-CN method, and on the unit hydrograph approach, that require daily observed and/or predicted rainfall, and temperature data as input. For the calibration of this model daily continuous time series of rainfall, streamflow and air temperature data are used. An event based lumped rainfall-runoff model has been, instead, used for the derivation of the rainfall thresholds for each catchment in Sicily characterised by an area larger than 50 km2. In particular, a Kinematic Instantaneous Unit Hydrograph based lumped rainfall-runoff model with the SCS-CN routine for net rainfall was developed for this purpose. For rainfall-induced shallow landslide warning, empirical rainfall thresholds provided by Gariano et al. (2015) have been included in the system. They were derived on an empirical basis starting from a catalogue of 265 shallow landslides in Sicily in the period 2002-2012. Finally, Delft-FEWS operational forecasting platform has been applied to link input data, SMA model and rainfall threshold models to produce warning on a daily basis for the entire region.
Beyond the biomedical: community resources for mental health care in rural Ethiopia.
Selamu, Medhin; Asher, Laura; Hanlon, Charlotte; Medhin, Girmay; Hailemariam, Maji; Patel, Vikram; Thornicroft, Graham; Fekadu, Abebaw
2015-01-01
The focus of discussion in addressing the treatment gap is often on biomedical services. However, community resources can benefit health service scale-up in resource-constrained settings. These assets can be captured systematically through resource mapping, a method used in social action research. Resource mapping can be informative in developing complex mental health interventions, particularly in settings with limited formal mental health resources. We employed resource mapping within the Programme for Improving Mental Health Care (PRIME), to systematically gather information on community assets that can support integration of mental healthcare into primary care in rural Ethiopia. A semi-structured instrument was administered to key informants. Community resources were identified for all 58 sub-districts of the study district. The potential utility of these resources for the provision of mental healthcare in the district was considered. The district is rich in community resources: There are over 150 traditional healers, 164 churches and mosques, and 401 religious groups. There were on average 5 eddir groups (traditional funeral associations) per sub-district. Social associations and 51 micro-finance institutions were also identified. On average, two traditional bars were found in each sub-district. The eight health centres and 58 satellite clinics staffed by Health Extension Workers (HEWs) represented all the biomedical health services in the district. In addition the Health Development Army (HDA) are community volunteers who support health promotion and prevention activities. The plan for mental healthcare integration in this district was informed by the resource mapping. Community and religious leaders, HEWs, and HDA may have roles in awareness-raising, detection and referral of people with mental illness, improving access to medical care, supporting treatment adherence, and protecting human rights. The diversity of community structures will be used to support rehabilitation and social reintegration. Alcohol use was identified as a target disorder for community-level intervention.
Beyond the Biomedical: Community Resources for Mental Health Care in Rural Ethiopia
Selamu, Medhin; Asher, Laura; Hanlon, Charlotte; Medhin, Girmay; Hailemariam, Maji; Patel, Vikram; Thornicroft, Graham; Fekadu, Abebaw
2015-01-01
Background The focus of discussion in addressing the treatment gap is often on biomedical services. However, community resources can benefit health service scale-up in resource-constrained settings. These assets can be captured systematically through resource mapping, a method used in social action research. Resource mapping can be informative in developing complex mental health interventions, particularly in settings with limited formal mental health resources. Method We employed resource mapping within the Programme for Improving Mental Health Care (PRIME), to systematically gather information on community assets that can support integration of mental healthcare into primary care in rural Ethiopia. A semi-structured instrument was administered to key informants. Community resources were identified for all 58 sub-districts of the study district. The potential utility of these resources for the provision of mental healthcare in the district was considered. Results The district is rich in community resources: There are over 150 traditional healers, 164 churches and mosques, and 401 religious groups. There were on average 5 eddir groups (traditional funeral associations) per sub-district. Social associations and 51 micro-finance institutions were also identified. On average, two traditional bars were found in each sub-district. The eight health centres and 58 satellite clinics staffed by Health Extension Workers (HEWs) represented all the biomedical health services in the district. In addition the Health Development Army (HDA) are community volunteers who support health promotion and prevention activities. Discussion The plan for mental healthcare integration in this district was informed by the resource mapping. Community and religious leaders, HEWs, and HDA may have roles in awareness-raising, detection and referral of people with mental illness, improving access to medical care, supporting treatment adherence, and protecting human rights. The diversity of community structures will be used to support rehabilitation and social reintegration. Alcohol use was identified as a target disorder for community-level intervention. PMID:25962075
NASA Astrophysics Data System (ADS)
Civitani, M.; Ghigo, M.; Basso, S.; Proserpio, L.; Spiga, D.; Salmaso, B.; Pareschi, G.; Tagliaferri, G.; Burwitz, V.; Hartner, G.; Menz, B.; Bavdaz, M.; Wille, E.
2013-09-01
X-ray telescopes with very large collecting area, like the proposed International X-ray Observatory (IXO, with around 3 m2 at 1 keV), need to be composed of a large number high quality mirror segments, aiming at achieving an angular resolution better than 5 arcsec HEW (Half-Energy-Width). A possible technology to manufacture the modular elements that will compose the entire optical module, named X-ray Optical Units (XOUs), consists of stacking in Wolter-I configuration several layers of thin foils of borosilicate glass, previously formed by hot slumping. The XOUs are subsequently assembled to form complete multi-shell optics with Wolter-I geometry. The achievable global angular resolution of the optic relies on the required surface shape accuracy of slumped foils, on the smoothness of the mirror surfaces and on the correct integration and co-alignment of the mirror segments. The Brera Astronomical Observatory (INAF-OAB) is leading a study, supported by ESA, concerning the implementation of the IXO telescopes based on thin slumped glass foils. In addition to the opto-mechanical design, the study foresees the development of a direct hot slumping thin glass foils production technology. Moreover, an innovative assembly concept making use of Wolter-I counter-form moulds and glass reinforcing ribs is under development. The ribs connect pairs of consecutive foils in an XOU stack, playing a structural and a functional role. In fact, as the ribs constrain the foil profile to the correct shape during the bonding, they damp the low-frequency profile errors still present on the foil after slumping. A dedicated semirobotic Integration MAchine (IMA) has been realized to this scope and used to build a few integrated prototypes made of several layers of slumped plates. In this paper we provide an overview of the project, we report the results achieved so far, including full illumination intra-focus X-ray tests of the last integrated prototype that are compliant with a HEW of around 17''.
Analysis of Variations in Hospital Use by Medicare Patients in Psro Areas, 1974-1977
Deacon, Ronald; Lubitz, James; Gornick, Marian; Newton, Marilyn
1979-01-01
A study of the use of short-stay hospitals in PSRO areas by Medicare enrollees aged 65 and over for the period 1974 through 1977 revealed that discharge rates increased, average length of stay (ALOS) decreased, and days-of-care rates remained relatively constant in nearly all of the PSRO areas. The data show large variations in hospital use in PSRO areas within States and HEW regions, and suggest that factors within the area are critical determinants of hospital utilization. This study presents important implications for PSRO program policy for it suggests that factors other than physician and hospital behavior should also be considered when setting objectives for reducing misutilization and improving the quality of health care. PMID:10309054
Remote-area health care delivery through space technology - STARPAHC
NASA Technical Reports Server (NTRS)
Belasco, N.; Johnston, R. S.; Stonesifer, J. C.; Pool, S. L.
1977-01-01
A joint NASA/HEW project called Space Technology Applied to Rural Papage Advanced Health Care (STARPAHC) has been developed to deliver quality health care to inhabitants of remote geographical areas. The system consists of a hospital-based support control center, a fixed clinic, a mobile clinic, and a referral center with access to specialists via television links to the control center. A strategically located relay station routes television, voice, and data transmissions between system elements. A model system has been installed on the Papage Indian Reservation in Arizona, and is undergoing a 2-year evaluation. The system has been shown to be both effective and cost-efficient, and applications of the concept are planned for future manned spacecraft flights.
1985-10-31
61A-51-045 (31 Oct 1985) --- San Francisco Bay and the San Andreas fault line stand out in this 70mm frame exposed from the Earth-orbiting Space Shuttle Challenger on October 31, 1985. The California coastline extends from Tomales Bay on the north almost to Santa Cruz (just out of frame) on the south. Parts of the Sacramento and San Joaquin valleys are seen along the frame's right edge. Some of the bay's salt evaporators are recognizable by their unique hews, near Fremont and near Vallejo. Center point coordinates are located at 37.5 degrees north latitude and 122.5 degrees west longitude. The Challenger was 180 nautical miles directly above a point centered at 38.8 degrees north latitude and 126.5 degrees west longitude.
NASA Astrophysics Data System (ADS)
Imkhovik, Nikolay A.
2010-10-01
Results of experimental and theoretical studies of the unusual detonation properties of mixtures of high explosives (HEs) with high-density inert additives W and Pb were analyzed and systematized. Typical examples of the nonideal detonation of composite explosives for which the measured detonation pressure is substantially lower and the detonation velocity is higher than the values calculated within the framework of the hydrodynamic model, with the specific heat ratio for the detonation products of ∼6-8, are presented. Mechanisms of formation of anomalous pressure and mass velocity profiles, which explain the correlation between the Chapman-Jouguet pressure for HE-W and HE-Pb mixtures, the velocity of the free surface of duralumin target, and the depth of the dent imprinted in steel witness plates, are described.
Coastal single-beam bathymetry data collected in 2015 from the Chandeleur Islands, Louisiana
Stalk, Chelsea A.; DeWitt, Nancy T.; Bernier, Julie C.; Kindinger, Jack G.; Flocks, James G.; Miselis, Jennifer L.; Locker, Stanley D.; Kelso, Kyle W.; Tuten, Thomas M.
2017-02-23
As part of the Louisiana Coastal Protection and Restoration Authority (CPRA) Barrier Island Comprehensive Monitoring Program, scientists from the U.S. Geological Survey (USGS) St. Petersburg Coastal and Marine Science Center conducted a single-beam bathymetry survey around the Chandeleur Islands, Louisiana, in June 2015. The goal of the program is to provide long-term data on Louisiana’s barrier islands and use this data to plan, design, evaluate, and maintain current and future barrier island restoration projects. The data described in this report, along with (1) USGS bathymetry data collected in 2013 as a part of the Barrier Island Evolution Research project covering the northern Chandeleur Islands, and (2) data collected in 2014 in collaboration with the Louisiana CPRA Barrier Island Comprehensive Monitoring Program around Breton Island, will be used to assess bathymetric change since 2006‒2007 as well as serve as a bathymetric control in supporting modeling of future changes in response to restoration and storm impacts. The survey area encompasses approximately 435 square kilometers of nearshore and back-barrier environments around Hewes Point, the Chandeleur Islands, and Curlew and Grand Gosier Shoals. This Data Series serves as an archive of processed single-beam bathymetry data, collected in the nearshore of the Chandeleur Islands, Louisiana, from June 17‒24, 2015, during USGS Field Activity Number 2015-317-FA. Geographic information system data products include a 200-meter-cell-size interpolated bathymetry grid, trackline maps, and xyz point data files. Additional files include error analysis maps, Field Activity Collection System logs, and formal Federal Geographic Data Committee metadata.
Gebrehiwot, Tesfay; San Sebastian, Miguel; Edin, Kerstin; Goicolea, Isabel
2014-04-10
Evidence shows that the three delays, delay in 1) deciding to seek medical care, 2) reaching health facilities and 3) receiving adequate obstetric care, are still contributing to maternal deaths in low-income countries. Ethiopia is a major contributor to the worldwide death toll of mothers with a maternal mortality ratio of 676 per 100,000 live births. The Ethiopian Ministry of Health launched a community-based health-care system in 2003, the Health Extension Programme (HEP), to tackle maternal mortality. Despite strong efforts, universal access to services remains limited, particularly skilled delivery attendance. With the help of 'the three delays' framework, this study explores health-service providers' perceptions of facilitators and barriers to the utilization of institutional delivery in Tigray, a northern region of Ethiopia. Twelve in-depth interviews were carried out with eight health extension workers (HEWs) and four midwives. Each interview lasted between 90 and 120 minutes. Data were analysed through a thematic analysis approach. Three themes emerged from the analysis: the struggle between tradition and newly acquired knowledge, community willingness to deal with geographical barriers, and striving to do a good job with insufficient resources. These themes represent the three steps in the path towards receiving adequate institutional delivery care at a health facility. Of the themes, 'increased community awareness', 'organization of the community' and 'hospital with specialized staff' were recognized as facilitators. On the other hand, 'delivery as a natural event', 'cultural tradition and rituals', 'inaccessible transport', 'unmet community expectation' and 'shortage of skilled human resources' were represented as barriers to institutional delivery. The participants in this study gave emphasis to the major barriers to institutional delivery that are closely connected with the three delays model. Despite the initiatives being implemented by the Tigray Regional Health Bureau, much is still needed to enhance the humanization approach of delivery care on a broader level of the region. A quick solution is needed to address the major issue of lack of transport accessibility. The poor capacity of the HEWs to provide delivery services, calls for reconsidering staffing patterns of remote health posts and readdressing the issue of downgraded health facilities would address unmet community needs.
Sales, Francisco; Pacheco, David; Blair, Hugh; Kenyon, Paul; McCoard, Sue
2013-01-01
Twin sheep fetuses have reduced skeletal muscle weight near birth relative to singles as a result of restricted muscle hypertrophy. Intracellular free amino acids (FAA) are reported to regulate metabolic pathways which control muscle protein accretion, whereby reduced intracellular content of specific FAA may reduce their activation and therefore, muscle hypertrophy. The aim of this study was to determine whether differences in muscle weight between singleton and twin fetuses, under different maternal conditions is associated with reduced concentration of specific FAA. The FAA content in the semitendinosus muscle (ST) in singleton and twin fetuses (rank) at 140 days of gestation from heavy (H) or light (L) ewes fed ad libitum (A) or maintenance (M) level of nutrition was measured. Muscle weight was reduced in twin fetuses compared to singletons in all groups. Reduced concentrations of leucine, threonine and valine, but higher concentrations of methionine, ornithine, lysine and serine were found in twin fetuses compared to singletons. Maternal size and nutrition interaction with rank resulted in reduced glutamine in twins from HM-ewes (H-ewes under M nutrition) compared to their singleton counterparts. Maternal weight interaction with pregnancy rank reduced the concentration of arginine in twins, with a larger effect on H-ewes compared with L-ewes. Maternal size interaction with pregnancy rank resulted in twins from M-ewes to have lower alanine, while twins from A-ewes had lower aspartic acid concentration compared to singletons. The ST muscle weight was positively correlated only with arginine concentration after taking into account rank, size and nutrition. The present results indicate that reduced concentrations of specific intracellular FAA, such as arginine, leucine, valine, glutamine, which are known to play a role in muscle growth, could be acting as limiting factors for muscle hypertrophy in twin fetuses during late gestation. Ewe size and nutrition can influence the concentration of specific FAA in muscle and should be considered in any intervention plan to improve twin fetal muscle growth.
Lenzenweger, Mark F.
2015-01-01
The concept of schizotypy represents a rich and complex psychopathology construct. Furthermore, the construct implies a theoretical model that has considerable utility as an organizing framework for the study of schizophrenia, schizophrenia-related psychopathology (eg, delusional disorder, psychosis-NOS (not otherwise specified), schizotypal, and paranoid personality disorder), and putative schizophrenia endophenotypes as suggested by Rado, Meehl, Gottesman, Lenzenweger, and others. The understanding (and misunderstanding) of the schizophrenia-related schizotypy model, particularly as regards clinical illness, as well as an alternative approach to the construct require vigilance in order to ensure the methodological approach continues to yield the fruit that it can in illuminating the pathogenesis of schizophrenia-related psychopathology. The articles in the Special Section in this issue of Schizophrenia Bulletin highlight methodological and theoretical issues that should be examined carefully. PMID:25810061
Effect of food additives on egg yolk gelation induced by freezing.
Primacella, Monica; Fei, Tao; Acevedo, Nuria; Wang, Tong
2018-10-15
This study demonstrates technological advances in preventing yolk gelation during freezing and thawing. Gelation negatively affects yolk functionality in food formulation. Preventing gelation using 10% salt or sugar limits the application of the yolk. Novel food additives were tested to prevent gelation induced by freezing. Significant reduction (p < 0.05) in gel hardness of frozen-thawed yolk (45 h freezing at -20 °C) indicates that hydrolyzed carboxymethyl cellulose (HCMC), proline, and hydrolyzed egg white and yolk (HEW and HEY) are effective gelation inhibitors. The mechanisms in which these additives prevented gelation were further studied through measuring the changes in the amount of freezable water, lipoprotein particle size, and protein surface hydrophobicity. Overall, this study provides several alternatives of gelation inhibitor that have great potentials in replacing the use of salt or sugar in commercial operation of freezing egg yolk for shelf-life extension. Copyright © 2018 Elsevier Ltd. All rights reserved.
Diagnosing the Nature of Land-Atmosphere Coupling: A Case Study of Dry/Wet Extremes
NASA Technical Reports Server (NTRS)
Santanello, Joseph A., Jr.; Peters-Lidard, Christa; Kennedy, Aaron D.
2012-01-01
Land-atmosphere (L-A) interactions play a critical role in determining the diurnal evolution of land surface and planetary boundary layer (PBL) temperature and moisture states and fluxes. In turn, these interactions regulate the strength of the connection between surface moisture and precipitation in a coupled system. To address deficiencies in numerical weather prediction and climate models due to improper treatment of L-A interactions, recent studies have focused on development of diagnostics to quantify the strength and accuracy of the land-PBL coupling at the process-level. In this study, a diagnosis of the nature and impacts oflocalland-atmosphere coupling (LoCo) during dry and wet extreme conditions is presented using a combination of models and observations during the summers of2006-7 in the U.S. Southern Great Plains. Specifically, the Weather Research and Forecasting (WRF) model has been coupled to NASA's Land Information System (LIS), which provides a flexible and high-resolution representation and initialization of land surface physics and states. A range of diagnostics exploring the links and feedbacks between soil moisture and precipitation are examined for the dry/wet regimes of this region, along with the behavior and accuracy of different land-PBL scheme couplings under these conditions. In addition, we examine the impact of improved specification ofland surface states, anomalies, and fluxes that are obtained through the use of a hew optimization and uncertainty module in LIS, on the L-A coupling in WRF forecasts. Results demonstrate how LoCo diagnostics can be applied to coupled model components in the context of their integrated impacts on the process-chain connecting the land surface to the PBL and support of hydrological anomalies.
Lavoie, Dawn; Flocks, James G.; Kindinger, Jack G.; Sallenger, A.H.; Twichell, David C.
2010-01-01
The State of Louisiana requested emergency authorization on May 11, 2010, to perform spill mitigation work on the Chandeleur Islands and on all the barrier islands from Grand Terre Island eastward to Sandy Point to enhance the capability of the islands to reduce the movement of oil from the Deepwater Horizon oil spill to the marshes. The proposed action-building a barrier berm (essentially an artificial island fronting the existing barriers and inlets) seaward of the existing barrier islands and inlets-'restores' the protective function of the islands but does not alter the islands themselves. Building a barrier berm to protect the mainland wetlands from oil is a new strategy and depends on the timeliness of construction to be successful. Prioritizing areas to be bermed, focusing on those areas that are most vulnerable and where construction can be completed most rapidly, may increase chances for success. For example, it may be easier and more efficient to berm the narrow inlets of the coastal section to the west of the Mississippi River Delta rather than the large expanses of open water to the east of the delta in the southern parts of the Breton National Wildlife Refuge (NWR). This document provides information about the potential available sand resources and effects of berm construction on the existing barrier islands. The proposed project originally involved removing sediment from a linear source approximately 1 mile (1.6 km) gulfward of the barrier islands and placing it just seaward of the islands in shallow water (~2-m depth where possible) to form a continuous berm rising approximately 6 feet (~2 m) above sea level (North American Vertical Datum of 1988-NAVD88) with an ~110-yd (~100-m) width at water level and a slope of 25:1 to the seafloor. Discussions within the U.S. Geological Survey (USGS) and with others led to the determination that point-source locations, such as Hewes Point, the St. Bernard Shoals, and Ship Shoal, were more suitable 'borrow' locations because sand content is insufficient along a linear track offshore from most of Louisiana's barrier islands. Further, mining sediment near the toe of the barrier island platform or edge of actively eroding barrier islands could create pits in the seafloor that will capture nearshore sand, thereby enhancing island erosion, and focus incoming waves (for example, through refraction processes) that could yield hotspots of erosion. In the Breton NWR, the proposed berm would be continuous from just south of Hewes Point to Breton Island for approximately 100 km with the exception of several passages for vessel access. Proposed volume estimates by sources outside of the USGS suggest that the structure in the Breton NWR would contain approximately 56 million cubic yards (42.8 m3) of sandy material. In the west, the berm would require approximately 36 million cubic yards (27.5 m3) of sandy material because this area has less open water than the area to the east of the delta. The planned berm is intended to protect the islands and inland areas from oil and would be sacrificial; that is, it will rapidly erode through natural processes. It is not part of the coastal restoration plan long discussed in Louisiana to rebuild barrier islands for hurricane protection of mainland infrastructure and habitat.
Negero, Melese Girmaye; Mitike, Yifru Berhan; Worku, Abebaw Gebeyehu; Abota, Tafesse Lamaro
2018-01-30
Because of the unacceptably high maternal and perinatal morbidity and mortality, the government of Ethiopia has established health extension program with a community-based network involving health extension workers (HEWs) and a community level women organization which is known as "Women's Health Development Army" (WHDA). Currently, the HEWs and WHDA network is the approach preferred by the government to register pregnant women and encourage them to link in the healthcare system. However, its association with skilled delivery service utilization is not well known. A community-based cross-sectional study was conducted from January to February 2015. Within 380 clusters of WHDA, a total of 748 reproductive-age women who gave birth in 1 year preceding the study, were included using multistage sampling technique. The data were entered into EPI info version 7 statistical software and exported to STATA version 11 for analysis. Multilevel analysis technique was applied to check for an association of selected variables with a utilization of skilled delivery service. About 45% of women have received skilled delivery care. A significant heterogeneity was observed between "Women's Health Development Teams (clusters)" for skilled delivery care service utilization which explains about 62% of the total variation. Individual-level predictors including urban residence [AOR (95% CI) 35.10 (4.62, 266.52)], previous exposure of complications [AOR (95% CI) 3.81 (1.60, 9.08)], at least four ANC visits [AOR (95% CI) 7.44 (1.48, 37.42)] and preference of skilled personnel [AOR (95% CI) 8.11 (2.61, 25.15)] were significantly associated with skilled delivery service use. Among cluster level variables, the distance of clusters within 2 km radius from the nearest health facility was significantly associated [AOR (95% CI) 6.03 (1.92, 18.93)] with skilled delivery service utilization. In this study, significant variation among clusters of WHDA was observed. Both individual and cluster level variables were identified to predict skilled delivery service utilization. Encouraging women to have frequent ANC visits (- 4 and above), enhancing awareness creation towards the delivery care attendance, constructing more health facilities and roads in hard to reach areas and establishing telemedicine services are recommended.
Investigation of He-W interactions using DiMES on DIII-D
NASA Astrophysics Data System (ADS)
Doerner, R. P.; Rudakov, D. L.; Chrobak, C. P.; Briesemeister, A. R.; Corr, C.; De Temmerman, G.; Kluth, P.; Lasnier, C. J.; McLean, A. G.; Pace, D. C.; Pitts, R. A.; Schmitz, O.; Thompson, M.; Winters, V.
2016-02-01
Tungsten button samples were exposed to He ELMing H-mode plasma in DIII-D using 2.3 MW of electron cyclotron heating power. Prior to the exposures, the W buttons were exposed to either He, or D, plasma in PISCES-A for 2000 s at surface temperatures of 225-850 °C to create a variety of surfaces (surface blisters, subsurface nano-bubbles, fuzz). Erosion was spectroscopically measured from each DiMES sample, with the exception of the fuzzy W samples which showed almost undetectable WI emission. Post-exposure grazing incidence small angle x-ray scattering surface analysis showed the formation of 1.5 nm diameter He bubbles in the surface of W buttons after only a single DIII-D (3 s, ˜150 ELMs) discharge, similar to the bubble layer resulting from the 2000 s. exposure in PISCES-A. No surface roughening, or damage, was detected on the samples after approximately 600 ELMs with energy density between 0.04-0.1 MJ m-2.
Spall, H.
1980-01-01
Sir Harold Jeffreys is a world authority in theoretical geophyiscs. hew as born in Northumbria (northeast of England) and educated at Armstrong College (now the University of Newcastle-upon-Tyne) and Cambridge University. He is now a Senior Fellow of St.John's College, Cambridge. He has published over 300 scientific papers and is the author of 7 books, including Theory of Probability and Mathematical Physics (with his wife, Lady Bertha Swirles Jeffreys). Sir Harold has made innumerable theoretical contributions to seismology. Many of these are documented in his book The Earth, which has been published in six editions. His papers have recently been collated by Gordon and Breach (Publishers) into six volumes, Collected Papers on Sir Harold Jeffreys on Geophyiscs and other Sciences. Some idea of the breadth of this research can be seen from the individual volume titles: "Theoretical and Observational Seismology," "Observational Seismology," "Gravity," "Dissipation of Energy and Thermal History," "Astronomy and Geophysics," and "Matematics, Probability and Miscellaneious Other Sciences."
Evaluation of eight short-term long-range transport models using field data
NASA Astrophysics Data System (ADS)
Carhart, R. A.; Policastro, A. J.; Wastag, M.; Coke, L.
Eight short-term long-range transport models (MESOPUFF, MESOPLUME, MSPUFF, MESOPUFF II, MTDDIS, ARRPA, RADM and RTM-II) have been tested with field data from two data bases involving tracer releases. The Oklahoma data base involved two separate experiments with measurements taken at 100 and 600 km arcs downwind of a 3-h perfluorocarbon release. The Savannah River Plant data base encompassed 15 experiments with measurements taken over 2-5 days at distances of 28-144 km downwind from a 62 m stack release of Kr-85 gas. Application of the American Meteorological Society statistics to the model/data comparisons showed that six of the eight models predicted within a factor of two of the observed concentrations for all of the following: points paired in space and time, points paired in space only, and for points unpaired in space and time. However, the ratio of the standard deviation of residuals to the average observed value showed improvement as more unpairing was done in the comparison of the models with the data. The statistical comparisons reveal a definite tendency of the models to overpredict plume concentrations. Supplemental graphical comparisons showed that plume concentration overprediction is accompanied with an underprediction of plume spreading, and that a definite time lag is often observed between the time of arrival of the observed plume and the time of arrival of the predicted plume. The causes of model/data discrepancies can be largely traced to inadequate wind field modeling that leads to an incorrect temporal and spatial positioning of the plume, and the use of the Turner [Workbook of atmospheric dispersion estimates. U.S. Dept of H.E.W. Publication 999-AP-26 (1970)] curves to downwind distances beyond which they can accurately represent the scales of atmospheric turbulence. The use of multilayer wind field models and the use of the Heffter [ J. appl. Met.4, 153-156 (1965)] formula for lateral plume dispersion close to the source appear to improve model accuracies.
Lavoie, Dawn
2009-01-01
Breton National Wildlife Refuge, the Chandeleur Islands chain in Louisiana, provides habitat and nesting areas for wildlife and is an initial barrier protecting New Orleans from storms. The U.S. Geological Survey (USGS) in partnership with the University of New Orleans Pontchartrain Institute for Environmental Sciences undertook an intensive study that included (1) an analysis of island change based on historical maps and remotely sensed shoreline and topographic data; (2) a series of lidar surveys at 3- to 4-month intervals after Hurricane Katrina to determine barrier island recovery potential; (3) a discussion of sea level rise and effects on the islands; (4) an analysis of sea floor evolution and sediment dynamics in the refuge over the past 150 years; (5) an assessment of the local sediment transport and sediment resource availability based on the bathymetric and subbottom data; (6) a carefully selected core collection effort to groundtruth the geophysical data and more fully characterize the sediments composing the islands and surrounds; (7) an additional survey of the St. Bernard Shoals to assess their potential as a sand resource; and (8) a modeling study to numerically simulate the potential response of the islands to the low-intensity, intermediate, and extreme events likely to affect the refuge over the next 50 years. Results indicate that the islands have become fragmented and greatly diminished in subaerial extent over time: the southern islands retreating landward as they reorganize into subaerial features, the northern islands remaining in place. Breton Island, because maintenance of the Mississippi River-Gulf Outlet (MRGO) outer bar channel requires dredging, is deprived of sand sufficient to sustain itself. Regional sediment transport trends indicate that large storms are extremely effective in transporting sand and controlling the shoreline development and barrier island geometry. Sand is transported north and south from a divergent zone near Monkey Bayou at the southern end of the Chandeleur Islands. Numerical simulation of waves and sediment transport supports the geophysical results and indicates that vast areas of the lower shoreface are affected and are undergoing erosion during storm events, that there is little or no fair weather mechanism to rework material into the littoral system, and that as a result, there is a net loss of sediment from the system. Lidar surveys revealed that the island chain immediately after Hurricane Katrina lost about 84 percent of its area and about 92 percent of its prestorm volume. Marsh platforms that supported the islands' sand prior to the storm were reduced in width by more than one-half. Repeated lidar surveys document that in places the shoreline has retreated about 100 m under the relatively low-energy waves since Hurricanes Katrina and Rita; however, this retreat is nonuniform. Recent high-resolution geophysical surveys of the sea floor and subsurface within 5-6 km of the Chandeleur Islands during 2006 and 2007 show that, in addition to the sand that is rebuilding portions of the island chain, a large volume of sand is contained in Hewes Point, in an extensive subtidal spit platform that has formed at the northern end of the Chandeleur Islands. Hewes Point appears to be the depositional terminus of the alongshore transport system. In the southern Chandeleurs, sand is being deposited in a broad tabular deposit near Breton Island called the southern offshore sand sheet. These two depocenters account for approximately 70 percent of the estimated sediment volume located in potential borrow sites. An additional large potential source of sand for restoration lies in the St. Bernard Shoals, which are estimated to contain approximately 200 ? 106 m3 of sand. Successful restoration planning for the Breton National Wildlife Refuge should mimic the natural processes of early stages of barrier island evolution including lateral transport to the flanks of the island chain
State administration and financing of family planning services.
Weinberg, D
1972-04-01
A 1971 survey by the Center for Family Planning Program Development consisted of a questionnaire mailed to health and welfare directors in 50 states and 5 federal jurisdictions concerning their family planning policies and administrative practices. 52 agencies responded; Guam, Mississippi, and Louisiana did not. The major funding for state health agencies was allocated by HEW and by maternal and child health (MCH) formula grants under Title 5 of the Social Security Act. 11 states made additional expenditures of $1.7 million for a variety of purposes. 21 states required local welfare departments to purchase services under the Medicaid program established by Title 19 of the Social Security Act. Administration was assigned to specific organizations within the state health agencies. 31 states reported a total of 128 full-time professional personnel, with 90 assigned at state headquarters level. In general, on a state-by-state basis, the full-time staff does not correspond to the size of the appropriations. Survey findings were useful measures of resource commitments to family planning services by state health and welfare agencies and provided data on future levels of resource requirements.
Comprehensive School Reform: Meta-Analytic Evidence of Black-White Achievement Gap Narrowing.
Gorey, Kevin M
2009-12-30
This meta-analysis extends a previous review of the achievement effects of comprehensive school reform (CSR) programs (Borman, Hewes, Overman, & Brown, 2003). That meta-analysis observed significant effects of well endowed and well-researched programs, but it did not account for race/ethnicity. This article synthesizes 34 cohort or quasi-experimental outcomes of studies that incorporated the policy-critical characteristic of race/ethnicity. compared with matched traditional schools, the black-white achievement gap narrowed significantly more among students in CSR schools. In addition, the aggregate effects were large, substantially to completely eliminating the achievement gap between African American and non-Hispanic white students in elementary and middle schools. Title I policies before or after the No Child Left Behind Act of 2001 seem to have had essentially no impact on the black-white achievement gap. Curricular and testing mandates along with the threat of sanctions without concomitant resource supports seem to have failed. This study suggests that educational achievement inequities need not be America's destiny. It seems that they could be eliminated through concerted political will and ample resource commitments to evidence-based educational programs.
Heim, Lori
2010-01-01
The new Consumer Alliance agreement between the American Academy of Family Physicians (AAFP) and The Coca-Cola Company provides a valuable opportunity to illustrate AAFP's adherence to its ethical foundation, demonstrate the AAFP's commitment to serving physicians and the public, and maintain the trust Americans put in their family physicians and the organization that represents them. Throughout the development of this program, as well as in all business interactions, the AAFP consistently addresses possible conflict of interest openly and directly, sharing with our members and the public exactly what measures we take to ensure that, in fact, no unethical conduct or breach of trust would--or will in the future--occur. In this case, the AAFP saw a public health and education need that was both unmet and undermined by the barrage of marketing messages and confusing information, and acted to fill that need. In so doing, the AAFP hewed to its high ethical standards, its core values, and its mission in the decisions made and the actions that followed.
Beyond the depleting model of parenting: narratives of childrearing and change.
Silva, Jennifer M; Pugh, Allison J
2010-01-01
A great deal of scholarship investigates the effects of parenting on adults who parent. While existing literature has identified the ways in which parenting affects parents adversely, we argue that more attention needs to be paid to how having children may enhance parents’ lives. Thus, we draw upon twenty-four in-depth interviews with young parents in order to investigate this process. First, we identify five ways in which parents say caregiving has changed their worldviews, relationships, and expectations, leading them to 1) erect barriers, 2) aspire for more, 3) view parenthood as a second chance, 4) hew a new path, and 5) make connections. Second, we uncover two central metaphors that parents rely on to explain the effect that having responsibility for children has had on their lives: the child as witness and the child as tether. We also point to future areas of investigation, arguing that only with an adequate understanding of what parenting does to parents can we understand what changing trends in families and inequality hold for ourselves and our futures.
INFINITY construction contract signed
2010-04-06
Key state and community leaders celebrated April 6 with the signing of a construction contract for the state-of-the-art INFINITY Science Center planned near John C. Stennis Space Center in south Mississippi. Gulfport Mayor George Schloegel (l to r), chair of non-profit INFINITY Science Center Inc., was joined for the signing ceremony at the Hancock Bank in Gulfport by Virginia Wagner, sister of late Hancock Bank President Leo Seal Jr.; and Roy Anderson III, president and CEO of Roy Anderson Corp. Seal was the first chair of INFINITY Science Center Inc., which has led in development of the project. Roy Anderson Corp. plans to begin construction on the 72,000-square-foot, $28 million science and education center in May. The Mississippi Department of Transportation (MDOT) also is set to begin construction of a $2 million access road to the new center. The April 6 ceremony was attended by numerous officials, including former Stennis Space Center Directors Jerry Hlass and Roy Estess; Mississippi Senate President Pro Tempore Billy Hewes, R-Gulfport; Mississippi Rep. Diane Peranich, D-Pass Christian; and MDOT Southern District Commissioner Wayne Brown.
INFINITY construction contract signed
NASA Technical Reports Server (NTRS)
2010-01-01
Key state and community leaders celebrated April 6 with the signing of a construction contract for the state-of-the-art INFINITY Science Center planned near John C. Stennis Space Center in south Mississippi. Gulfport Mayor George Schloegel (l to r), chair of non-profit INFINITY Science Center Inc., was joined for the signing ceremony at the Hancock Bank in Gulfport by Virginia Wagner, sister of late Hancock Bank President Leo Seal Jr.; and Roy Anderson III, president and CEO of Roy Anderson Corp. Seal was the first chair of INFINITY Science Center Inc., which has led in development of the project. Roy Anderson Corp. plans to begin construction on the 72,000-square-foot, $28 million science and education center in May. The Mississippi Department of Transportation (MDOT) also is set to begin construction of a $2 million access road to the new center. The April 6 ceremony was attended by numerous officials, including former Stennis Space Center Directors Jerry Hlass and Roy Estess; Mississippi Senate President Pro Tempore Billy Hewes, R-Gulfport; Mississippi Rep. Diane Peranich, D-Pass Christian; and MDOT Southern District Commissioner Wayne Brown.
NASA Astrophysics Data System (ADS)
Civitani, M.; Basso, S.; Brizzolari, C.; Ghigo, M.; Pareschi, G.; Salmaso, B.; Spiga, D.; Vecchi, G.; Breunig, E.; Burwitz, V.; Hartner, G. D.; Menz, B.
2015-09-01
The Slumped Glass Optics technology, developed at INAF/OAB since a few years, is becoming a competitive solution for the realization of the future X-ray telescopes with a very large collecting area, as e.g. the proposed Athena, with more than 2 m2 effective area at 1 keV and with a high angular resolution (5'' HEW). The developed technique is based on modular elements, named X-ray Optical Units (XOUs), made of several layers of thin foils of glass, previously formed by direct hot slumping in cylindrical configuration, and then stacked in a Wolter-I configuration, through interfacing ribs. The achievable global angular resolution of the optics relies on the surface shape accuracy of the slumped foils, on the smoothness of the mirror surfaces and on the correct integration and co-alignment of the mirror segments achieved with a dedicated Integration Machine (IMA). In this paper we provide an update of the project development, reporting on the last results achieved. In particular, we will present the results obtained with full illumination X-ray tests for the last developed prototypes.
Heim, Lori
2010-01-01
The new Consumer Alliance agreement between the American Academy of Family Physicians (AAFP) and The Coca-Cola Company provides a valuable opportunity to illustrate AAFP’s adherence to its ethical foundation, demonstrate the AAFP’s commitment to serving physicians and the public, and maintain the trust Americans put in their family physicians and the organization that represents them. Throughout the development of this program, as well as in all business interactions, the AAFP consistently addresses possible conflict of interest openly and directly, sharing with our members and the public exactly what measures we take to ensure that, in fact, no unethical conduct or breach of trust would—or will in the future—occur. In this case, the AAFP saw a public health and education need that was both unmet and undermined by the barrage of marketing messages and confusing information, and acted to fill that need. In so doing, the AAFP hewed to its high ethical standards, its core values, and its mission in the decisions made and the actions that followed. PMID:20644192
Comprehensive School Reform: Meta-Analytic Evidence of Black-White Achievement Gap Narrowing1
Gorey, Kevin M.
2016-01-01
This meta-analysis extends a previous review of the achievement effects of comprehensive school reform (CSR) programs (Borman, Hewes, Overman, & Brown, 2003). That meta-analysis observed significant effects of well endowed and well-researched programs, but it did not account for race/ethnicity. This article synthesizes 34 cohort or quasi-experimental outcomes of studies that incorporated the policy-critical characteristic of race/ethnicity. Findings: compared with matched traditional schools, the black-white achievement gap narrowed significantly more among students in CSR schools. In addition, the aggregate effects were large, substantially to completely eliminating the achievement gap between African American and non-Hispanic white students in elementary and middle schools. Title I policies before or after the No Child Left Behind Act of 2001 seem to have had essentially no impact on the black-white achievement gap. Curricular and testing mandates along with the threat of sanctions without concomitant resource supports seem to have failed. This study suggests that educational achievement inequities need not be America’s destiny. It seems that they could be eliminated through concerted political will and ample resource commitments to evidence-based educational programs. PMID:27453681
The Failure of the 1976 Swine Influenza Immunization Program
Begley, Sharon L.
1977-01-01
The program to immunize 210 million Americans against swine flu failed. It set back the Federal government's relations with state health agencies, private physicians, pharmaceutical manufacturers, and the insurance industry. It increased mistrust of immunization programs and of government health programs in general. The well-intentioned plan had far-reaching consequences because its scope and the speed with which it was implemented were overreactions to the threat. Its size magnified every one of its faults, legal, medical and political. Organizational and scientific capacity were less than expected. Local health agencies could not administer the program with the inadequate funds from HEW and pharmaceutical companies could not produce a safe, effective children's vaccine. Because of the urgency given the program, Congress neglected the opposition of consumer advocates and state health officials, and did not spend time trying to include immunization against childhood disease in the swine flu program. The failure illustrates the dangers of hasty decisions, of considering only direct medical costs and benefits and not social and political effects on health policy, of launching a public health program whose scientific basis is weak and whose administrative requirements are untested. PMID:610056
Smallridge, Robert C
2014-12-01
The history of postpartum thyroid dysfunction (PPTD) dates back almost two millennia, when Soranus of Ephesus, who practiced obstetrics and neonatology, observed swelling in the necks (presumably goiters) of women after pregnancy. The next reference to PPTD appeared in artwork more than 1000 years later, with many portraits illustrating women with goiter while holding infants. In the early to mid-19th century, Caleb Hillier Parry and Armand Trousseau described postpartum hyperthyroidism, while in the late 1800s, Sir Horatio Bryan Donkin reported the first patient with postpartum hypothyroidism. The modern era of PPTD began with the description in the late 1940s by H.E.W. Roberton of women after delivery reporting hypothyroid symptoms and responding to thyroid extract. The immunologic influence on PPTD was recognized initially by Parker and Beierwaltes in the early 1960s, and the clinical variability and natural history were carefully documented by numerous investigators in the 1970s-1980s. The past two decades have seen further refinements in understanding the prevalence, etiology, and treatment of PPTD. Yet to be determined is the role of screening as a cost-effective measure.
Confocal Raman study of aging process in diabetes mellitus human voluntaries
NASA Astrophysics Data System (ADS)
Pereira, Liliane; Téllez Soto, Claudio Alberto; dos Santos, Laurita; Ali, Syed Mohammed; Fávero, Priscila Pereira; Martin, Airton A.
2015-06-01
Accumulation of AGEs [Advanced Glycation End - products] occurs slowly during the human aging process. However, its formation is accelerated in the presence of diabetes mellitus. In this paper, we perform a noninvasive analysis of glycation effect on human skin by in vivo confocal Raman spectroscopy. This technique uses a laser of 785 nm as excitation source and, by the inelastic scattering of light, it is possible to obtain information about the biochemical composition of the skin. Our aim in this work was to characterize the aging process resulting from the glycation process in a group of 10 Health Elderly Women (HEW) and 10 Diabetic Elderly Women (DEW). The Raman data were collected from the dermis at a depth of 70-130 microns. Through the theory of functional density (DFT) the bands positions of hydroxyproline, proline and AGEs (pentosidine and glucosepane) were calculated by using Gaussian 0.9 software. A molecular interpretation of changes in type I collagen was performed by the changes in the vibrational modes of the proline (P) and hydroxyproline (HP). The data analysis shows that the aging effects caused by glycation of proteins degrades type I collagen differently and leads to accelerated aging process.
The PSRO hospital review system.
Goran, M J; Roberts, J S; Kellogg, M A; Fielding, J; Jessee, W
1975-04-01
The 1972 Social Security amendments contained the landmark Professional Standards Review Organization (PSRO) provisions as well as several sections upgrading existing utilization review (UR) requirements under Medicare and Medicaid. With issuance of the PSRO Program Manual and the recent publication of the new UR regulations, HEW for the first time has brought Medicare and Medicaid hospital review requirements into conformity and made them compatible with and supportive of the PSRO program. This article defines the PSRO hospital review system, describes how the three major components-concurrent review, medical care evaluation studies, and profile analysis-interrelate and provides examples of each of these components. Under utilization review requirements or PSRO, hospitals will be required to implement an integrated system of review designed to assure appropriate utilization practices and improve the quality of care. These aims are to be accomplished through the application of concepts of peer review, the use of norms, criteria, and standards, the identification of deficiencies in the quality, administration, or appropriateness of health care services, and their correction through linkage with programs of continuing medical education. Although PSROs are initially responsible for review in hospitals, they will likely provide the locus for a community-wide system of peer review for all services provided under National Health Insurance.
NASA Astrophysics Data System (ADS)
Civitani, M. M.; Hołyszko, J.; Vecchi, G.; Basso, S.; Citterio, O.; Ghigo, M.; Pareschi, G.; Parodi, G.; Incorvaia, S.
2017-09-01
The implementation of an X-ray mission with high imaging capabilities, similar to those achieved with Chandra (< 1 arc second Half Energy Width, HEW), but with a much larger throughput (2.5 m2 effective area @1 keV), represents a compelling request by the scientific community. To this end the Lynx/XRS mission is being studied in USA, with the participation of international partners. In order to figure out the challenging technological task of the mirror fabrication, different approaches are considered, based on monolithic and segmented shells. Starting from the experience done on the glass prototypal shell realized in the past years, the direct polishing of thin (2 mm thick) fused silica monolithic shells is being investigated as a possible solution. A temporary stiffening structure is designed to support the shell during the figuring and polishing operations and to manage the handling up to its integration in the telescope structure. After the grinding and the polishing phases, in order to achieve the required surface accuracy, a final ion beam figuring correction is foreseen. In this paper, we present the technological process and the results achieved so far on a prototypal shell under development.
Diurnal, seasonal and inter-annual variations in the Schumann resonance parameters
NASA Astrophysics Data System (ADS)
Price, Colin; Melnikov, Alexander
2004-09-01
The Schumann resonances (SR) represent an electromagnetic phenomenon in the Earth's atmosphere related to global lightning activity. The spectral characteristics of the SR modes are defined by their resonant mode amplitude, center frequency and half-width (Q-factor). Long-term (4 years) diurnal and seasonal variations of these parameters are presented based on measurements at a field site in the Negev desert, Israel. Variations of the different modes (8, 14 and 20Hz) and the different electromagnetic components (Hns, Hew and Ez) are presented. The power variations of the various modes and components show three dominant maxima in the diurnal cycle related to lightning activity in south-east Asia (0800UT), Africa (1400UT) and South America (2000UT). The largest global lightning activity occurs during the northern hemisphere summer (JJA) with the southern hemisphere summer (DJF) having the least lightning around the globe. The frequency and half-width (Q-factor) variations of the different modes and SR components are fairly complicated in structure, and will need additional theoretical work to explain their variations. However, the frequency variations are in excellent agreement with previous studies, implying that the frequency variations are robust features of the SR. The inter-annual variability of global lightning activity is shown to vary differently for each of the three major source regions of global lightning.
Ameha, Agazi; Karim, Ali Mehryar; Erbo, Amano; Ashenafi, Addis; Hailu, Mulu; Hailu, Berhan; Folla, Abebe; Bizuwork, Simret; Betemariam, Wuleta
2014-10-01
Consistency in the adherence to integrated Community Case Management (iCCM) protocols for common childhood illnesses provided by Ethiopia's Health Extension Program (HEP) frontline workers. One approach is to provide regular clinical mentoring to the frontline health workers of the HEP at their health posts (HP) through supportive supervision (SS) following the initial training. To Assess the effectiveness of visits to improve the consistency of iCCM skills (CoS) of the HEWs in 113 districts in Ethiopia. We analyzed data from 3,909 supportive supervision visits between January 2011 and June 2013 in 113 districts in Ethiopia. From case assessment registers, a health post was classified as consistent in managing pneumonia, malaria, or diarrhea cases if the disease classification, treatment, and follow-up of the last two cases managed at the health posts were consistent with the protocol. We used regression models to assess the effects of SS on CoS. All HPs (2,368) received at least one supportive supervision visit, 41% received two, and 15% received more than two. During the observation period, HP management consistency in pneumonia, malaria, and diarrhea increased by 3.0, 2.7 and 4.4-fold, respectively. After controlling for secular trend and other factors, significant dose-response relationships were observed between number of SS visits and CoS indicators. The SS visits following the initial training were effective in improving the CoS.
Manufacturing and testing a thin glass mirror shell with piezoelectric active control
NASA Astrophysics Data System (ADS)
Spiga, D.; Barbera, M.; Collura, A.; Basso, S.; Candia, R.; Civitani, M.; Di Bella, M.; Di Cicca, G.; Lo Cicero, U.; Lullo, G.; Pelliciari, C.; Riva, M.; Salmaso, B.; Sciortino, L.; Varisco, S.
2015-09-01
Optics for future X-ray telescopes will be characterized by very large aperture and focal length, and will be made of lightweight materials like glass or silicon in order to keep the total mass within acceptable limits. Optical modules based on thin slumped glass foils are being developed at various institutes, aiming at improving the angular resolution to a few arcsec HEW. Thin mirrors are prone to deform, so they require a careful integration to avoid deformations and even correct forming errors. On the other hand, this offers the opportunity to actively correct the residual deformation: a viable possibility to improve the mirror figure is the application of piezoelectric actuators onto the non-optical side of the mirrors, and several groups are already at work on this approach. The concept we are developing consists of actively integrating thin glass foils with piezoelectric patches, fed by voltages driven by the feedback provided by X-rays. The actuators are commercial components, while the tension signals are carried by a printed circuit obtained by photolithography, and the driving electronic is a multi-channel low power consumption voltage supply developed inhouse. Finally, the shape detection and the consequent voltage signal to be provided to the piezoelectric array are determined in X-rays, in intra-focal setup at the XACT facility at INAF/OAPA. In this work, we describe the manufacturing steps to obtain a first active mirror prototype and the very first test performed in X-rays.
Report on health and environmental effects of increased coal utilization*
1980-01-01
The National Energy Plan announced by President Carter on April 29, 1977 proposed a significant increase in the utilization of the vast domestic deposits of coal to replace the dwindling supplies of oil and natural gas, and increasingly expensive oil from foreign sources, to meet national energy needs. At the same time, in recognition of possible adverse health and ecological consequences of increased coal production and use, the President announced that a special committee would be formed to study this aspect of the National Energy Plan. The Committee held a series of public meetings during November and December 1977 to review a number of special papers on particular problems associated with increased coal utilization. These papers, which were prepared by scientists of the US Environmental Protection Agency; the Department of Energy; the HEW National Institute for Occupational Safety and Health, and the National Institute of Environmental Health Sciences; New York University; and Vanderbilt University; provided essential background information for the deliberations of the Committee and were published in EHP Vol. 33, pp. 127–314, 1979. One paper by A. P. Altschuler et al. is published in this volume of EHP. The Committee's basic finding was that it is safe to proceed with plans to increase the utilization of coal if the following environmental and safety policies are adhered to: • Compliance with Federal and State air, water, and solid waste regulations • Universal adoption and successful operation of best available control technology on new facilities • Compliance with reclamation standards • Compliance with mine health and safety standards • Judicious siting of coal-fired facilities The Committee concluded that, even with the best mitigation policies, there will be some adverse health and environmental effects from the dramatic increase in coal use. However, these will not impact all regions and individuals uniformly. The Committee identified six major areas of uncertainty and concern requiring further investigation if the nation is to minimize undesirable consequences of increased coal utilization now, and in the future. Two critical health issues of concern are air pollution health effects and coal mine worker health and safety. Two critical environmental issues are global effects of carbon dioxide in the atmosphere and acid fallout. Two additional important issues of concern are trace elements in the environment and reclamation of arid land. Finally, because of the inadequate data and methodology used in the study of these matters, the Committee strongly recommended the establishment of an improved national environmental data collection, modeling and monitoring system. PMID:6775943
1980-06-01
The National Energy Plan announced by President Carter on April 29, 1977 proposed a significant increase in the utilization of the vast domestic deposits of coal to replace the dwindling supplies of oil and natural gas, and increasingly expensive oil from foreign sources, to meet national energy needs. At the same time, in recognition of possible adverse health and ecological consequences of increased coal production and use, the President announced that a special committee would be formed to study this aspect of the National Energy Plan. The Committee held a series of public meetings during November and December 1977 to review a number of special papers on particular problems associated with increased coal utilization. These papers, which were prepared by scientists of the US Environmental Protection Agency; the Department of Energy; the HEW National Institute for Occupational Safety and Health, and the National Institute of Environmental Health Sciences; New York University; and Vanderbilt University; provided essential background information for the deliberations of the Committee and were published in EHP Vol. 33, pp. 127-314, 1979. One paper by A. P. Altschuler et al. is published in this volume of EHP. The Committee's basic finding was that it is safe to proceed with plans to increase the utilization of coal if the following environmental and safety policies are adhered to:* Compliance with Federal and State air, water, and solid waste regulations* Universal adoption and successful operation of best available control technology on new facilities* Compliance with reclamation standards* Compliance with mine health and safety standards* Judicious siting of coal-fired facilitiesThe Committee concluded that, even with the best mitigation policies, there will be some adverse health and environmental effects from the dramatic increase in coal use. However, these will not impact all regions and individuals uniformly. The Committee identified six major areas of uncertainty and concern requiring further investigation if the nation is to minimize undesirable consequences of increased coal utilization now, and in the future. Two critical health issues of concern are air pollution health effects and coal mine worker health and safety. Two critical environmental issues are global effects of carbon dioxide in the atmosphere and acid fallout. Two additional important issues of concern are trace elements in the environment and reclamation of arid land.Finally, because of the inadequate data and methodology used in the study of these matters, the Committee strongly recommended the establishment of an improved national environmental data collection, modeling and monitoring system.
Weidert, Karen; Gessessew, Amanuel; Bell, Suzanne; Godefay, Hagos; Prata, Ndola
2017-03-24
Ethiopia has made notable progress in increasing awareness and knowledge of family planning and is considered a success story among funders and program planners. Yet unmet need among rural women (28.6%) is almost double that of urban women (15.5%), with a wide gap in total fertility rate depending on urban (2.6) or rural (5.5) residence. This study investigates the impact of a service delivery model that combines community-based distribution (CBD) of contraception with social marketing in Tigray, Ethiopia, to create a more sustainable approach to CBD. Between September 2011 and October 2013, 626 volunteer CHWs were recruited and trained to administer depot medroxyprogesterone acetate (DMPA) injections and provide counseling and referrals to the health post for other methods; the project implementation period ended in June 2014. The CHWs received a supply of DMPA injections in the form of a microloan from a drug revolving fund; the CHWs charged women a minimal fee (5 birr, or US$0.29), determined based on willingness-to-pay data, for each DMPA injection; and the CHWs returned part of the fee (3 birr) to the drug revolving fund while keeping the remaining portion (2 birr). The CHWs also promoted demand for family planning through door-to-door outreach and community meetings. Existing health extension workers (HEWs) provided regular supervision of the CHWs, supplemented by in-depth supervision visits from study coordinators. Baseline and endline representative surveys of women of reproductive age, as well as of participating CHWs, were conducted. In addition, DMPA provision data from the CHWs were collected. Between October 2011 and June 2014, the CHWs served in total 8,604 women and administered an estimated 15,410 DMPA injections, equivalent to providing 3,853 couple-years of protection. There was a 25% significant increase in contraceptive use among surveyed women, from 30.1% at baseline to 37.7% at endline, with DMPA use largely responsible for this increase. Changes in quality of family planning markers from baseline suggested services improved between baseline and endline: nearly 50% more women reported being told about side effects and what to do if they experience side effects, and 25% more women said they were told about other methods of contraception. The results from household surveys at baseline and endline suggest that CHWs in this model made a significant contribution to family planning in the region. © Weidert et al.
Weidert, Karen; Gessessew, Amanuel; Bell, Suzanne; Godefay, Hagos; Prata, Ndola
2017-01-01
ABSTRACT Ethiopia has made notable progress in increasing awareness and knowledge of family planning and is considered a success story among funders and program planners. Yet unmet need among rural women (28.6%) is almost double that of urban women (15.5%), with a wide gap in total fertility rate depending on urban (2.6) or rural (5.5) residence. This study investigates the impact of a service delivery model that combines community-based distribution (CBD) of contraception with social marketing in Tigray, Ethiopia, to create a more sustainable approach to CBD. Between September 2011 and October 2013, 626 volunteer CHWs were recruited and trained to administer depot medroxyprogesterone acetate (DMPA) injections and provide counseling and referrals to the health post for other methods; the project implementation period ended in June 2014. The CHWs received a supply of DMPA injections in the form of a microloan from a drug revolving fund; the CHWs charged women a minimal fee (5 birr, or US$0.29), determined based on willingness-to-pay data, for each DMPA injection; and the CHWs returned part of the fee (3 birr) to the drug revolving fund while keeping the remaining portion (2 birr). The CHWs also promoted demand for family planning through door-to-door outreach and community meetings. Existing health extension workers (HEWs) provided regular supervision of the CHWs, supplemented by in-depth supervision visits from study coordinators. Baseline and endline representative surveys of women of reproductive age, as well as of participating CHWs, were conducted. In addition, DMPA provision data from the CHWs were collected. Between October 2011 and June 2014, the CHWs served in total 8,604 women and administered an estimated 15,410 DMPA injections, equivalent to providing 3,853 couple-years of protection. There was a 25% significant increase in contraceptive use among surveyed women, from 30.1% at baseline to 37.7% at endline, with DMPA use largely responsible for this increase. Changes in quality of family planning markers from baseline suggested services improved between baseline and endline: nearly 50% more women reported being told about side effects and what to do if they experience side effects, and 25% more women said they were told about other methods of contraception. The results from household surveys at baseline and endline suggest that CHWs in this model made a significant contribution to family planning in the region. PMID:28275087
Desalegn, Ketsela; Loha, Eskindir; Meskele, Mengistu
2017-01-01
Objective: Family Planning is often taken as one of the “Magic Bullet” interventions owing to its high impact and wide reaching nature in achieving multiple goals. This study aimed to assess the current status and the factors associated with health post level Implanon service provision through trained health extension workers in Wolaita zone, southern Ethiopia. Materials and methods: A cross sectional study was conducted among trained health extension workers in Wolaita zone in February 2013. A simple random sampling technique was used to identify a total of 285 trained HEWs. First bivariate, then multivariate logistic regression model along with 95% confidence interval was used to see the independent effect of factors associated with current Implanon service provision by the health extension workers. Results: Currently, the number of Implaon providing trained health extension workers in Wolaita was 264(45.8%). Distance of health post from district health offices and health center, turnover of trained health extension workers in the health post, interest of trained health extension workers in providing Implanon and their job satisfaction to serve as a health extension workers and availability of service delivery guidelines and teaching aids were associated with the current provision of Implanon by health extension workers. Conclusion: Implanon provision among trained health extension workers was affected by different factors. Hence, improving the working conditions of trained health extension workers, regular and periodic facilitative supervision, availing service delivery guidelines and improvement of health management information system are recommended. PMID:29114263
NASA Astrophysics Data System (ADS)
Civitani, M. M.; Basso, S.; Bavdaz, M.; Citterio, O.; Conconi, P.; Gallieni, D.; Ghigo, M.; Martelli, F.; Pareschi, G.; Parodi, G.; Proserpio, L.; Sironi, G.; Spiga, D.; Tagliaferri, G.; Tintori, M.; Wille, E.; Zambra, A.
2011-09-01
The International X-ray Observatory (IXO) is a joint mission concept studied by the ESA, NASA, and JAXA space agencies. The main goal of the mission design is to achieve a large effective area (>2.5m2 at 1 keV) and a good angular resolution (5 arcsec HEW at 1 keV) at the same time. The Brera Astronomical Observatory - INAF, Italy), under the support of ESA, is developing a method for the realization of the X-Ray Optical Units, based on the use of slumped thin glass segments to form densely packed modules in a Wolter type I optical configuration. In order to reach the very challenging integration requirements, it has been developed an innovative assembly approach for aligning and mounting the IXO mirror segments. The method is based on the use of an integration mould for each foil. In particular the glass segment is forced to adhere to the integration mould in order to maintain the optimal figure without deformations until the integration of the foil in the stack is completed. In this way an active correction for major existing figure errors after slumping is also achieved. Moreover reinforcing ribs are used in order to connect the facets to each-other and to realize a robust monolithic stack of plates. In this paper we present the design, the development and the validation status of a special Integration Machine (IMA) that has been specifically developed to allow the integration of the Plate Pairs into prototypal X-Ray Optical Unit stacks.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Saltzman, S.E.
1977-01-01
Energy is considered as part of a complex of resources and technologies, the effects of which are both interdisciplinary and transnational. This symposium took place at the height of the energy crisis, being planned long in advance. Elizabeth Mann Borgese presented an introductory paper. N.B. Guyol presented as Energy Overview, World Energy Requirements and Supplies, 1970--2000. Part I, Science and Technology Aspects, contains 5 papers: Some Problems Posed by the Growing Demand for Energy, Jacques Piccard; Solar Energy, A Key to Global Survival, William E. Heronemus; The Fast Breeder as a Cornerstone for Future Large Supplies of Energy, Wolf Hafele;more » Fusion Reactors as FUture Energy Sources, R. F. Post and F. L. Ribe; Energy Needs and the Atmosphere, Wendell Mordy. Part II, Interdisciplinary and Policy Aspects, contains 10 papers: A Survey of Internaational Energy Institutions and Policy Mechanisms, Keith J. Walton; A Crude but Plausible Model for Worldwide Energy Needs into the Next Century, Bernard T. Feld; Rural Progress and the Role of Energy among LDCs, Laurence I. Hewes, Jr.; Energy and Poorer Countries: the Context of a Strategy, Norton Ginsburg; Energy, Money, and International Trade, Ronald Segal; Peaceful Nuclear Power as a Military Equalizer, David Krieger; Energy and the Oceans, Elizabeth Mann Borgese; Research Priorities on Global Energy Policy Issues: A suggested Analtytical Framework, John Hanessian, Jr. and Jean M. Johnson; World Energy Model: A Tool for Long-Term Planning, Mihajlo Mesarovic and Eduard Pestel; and Proposal for the Establishment of an International Energy Institute, Elizabeth Mann Borgese. (MCW)« less
Grol-Prokopczyk, Hanna
2013-01-01
Recent scholarship argues that successful international medical collaboration depends crucially on improving cross-cultural understanding. To this end, this study analyzes recent writings on medical ethics by physicians in two countries actively participating in global medicine, Thailand and the United States. Articles (133; published 2004-2008) from JAMA, the New England Journal of Medicine, and the Journal of the Medical Association of Thailand are analyzed to inductively build a portrait of two discursive ethical cultures. Frameworks of moral reasoning are identified across and within the two groups, with a focus on what authority (religion, law, etc.) is invoked to define and evaluate ethical problems. How might similarities and differences in ethical paradigms reflect the countries' historical "semicolonial" relationship, shed light on debates about Eastern vs. Western bioethics, and facilitate or hinder contemporary cross-national communication? Findings demonstrate substantial overlap in Thai and American doctors' vocabulary, points of reference, and topics covered, though only Thai doctors emphasize national interests and identity. American authors display a striking homogeneity in styles of moral reasoning, embracing a secular, legalistic, deontological ethics that generally eschews discussion of religion, personal character, or national culture. Among Thai authors, there is a schism in ethical styles: while some hew closely to the secular, deontological model, others embrace a virtue ethics that liberally cites Buddhist principles and emphasizes the role of doctors' good character. These two approaches may represent opposing reactions-assimilation and resistance, respectively-to Western influence. The current findings undermine the stereotype of Western individualism versus Eastern collectivism. Implications for cross-national dialog are discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.
Heat and water rate transfer processes in the human respiratory tract at various altitudes.
Kandjov, I M
2001-02-01
The process of the respiratory air conditioning as a process of heat and mass exchange at the interface inspired air-airways surface was studied. Using a model of airways (Olson et al., 1970) where the segments of the respiratory tract are like cylinders with a fixed length and diameter, the corresponding heat transfer equations, in the paper are founded basic rate exchange parameters-convective heat transfer coefficient h(c)(W m(-2) degrees C(-1)) and evaporative heat transfer coefficient h(e)(W m(-2)hPa(-1)). The rate transfer parameters assumed as sources with known heat power are connected to airflow rate in different airways segments. Relationships expressing warming rate of inspired air due to convection, warming rate of inspired air due to evaporation, water diffused in the inspired air from the airways wall, i.e. a system of air conditioning parameters, was composed. The altitude dynamics of the relations is studied. Every rate conditioning parameter is an increasing function of altitude. The process of diffusion in the peripheral bronchial generations as a basic transfer process is analysed. The following phenomenon is in effect: the diffusion coefficient increases with altitude and causes a compensation of simultaneous decreasing of O(2)and CO(2)densities in atmospheric air. Due to this compensation, the diffusion in the peripheral generations with altitude is approximately constant. The elements of the human anatomy optimality as well as the established dynamics are discussed and assumed. The square form of the airways after the trachea expressed in terms of transfer supposes (in view of maximum contact surface), that a maximum heat and water exchange is achieved, i.e. high degree of air condition at fixed environmental parameters and respiration regime. Copyright 2001 Academic Press.
BEaTriX, expanded x-ray beam facility for testing modular elements of telescope optics: an update
NASA Astrophysics Data System (ADS)
Pelliciari, C.; Spiga, D.; Bonnini, E.; Buffagni, E.; Ferrari, C.; Pareschi, G.; Tagliaferri, G.
2015-09-01
We present in this paper an update on the design of BEaTriX (Beam Expander Testing X-ray facility), an X-ray apparatus to be realized at INAF/OAB and that will generate an expanded, uniform and parallel beam of soft X-rays. BEaTriX will be used to perform the functional tests of X-ray focusing modules of large X-ray optics such as those for the ATHENA X-ray observatory, using the Silicon Pore Optics (SPO) as a baseline technology, and Slumped Glass Optics (SGO) as a possible alternative. Performing the tests in X-rays provides the advantage of an in-situ, at-wavelength quality control of the optical modules produced in series by the industry, performing a selection of the modules with the best angular resolution, and, in the case of SPOs, there is also the interesting possibility to align the parabolic and the hyperbolic stacks directly under X-rays, to minimize the aberrations. However, a parallel beam with divergence below 2 arcsec is necessary in order to measure mirror elements that are expected to reach an angular resolution of about 4 arcsec, since the ATHENA requirement for the entire telescope is 5 arcsec. Such a low divergence over the typical aperture of modular optics would require an X-ray source to be located in a several kilometers long vacuum tube. In contrast, BEaTriX will be compact enough (5 m x 14 m) to be housed in a small laboratory, will produce an expanded X-ray beam 60 mm x 200 mm broad, characterized by a very low divergence (1.5 arcsec HEW), strong polarization, high uniformity, and X-ray energy selectable between 1.5 keV and 4.5 keV. In this work we describe the BEaTriX layout and show a performance simulation for the X-ray energy of 4.5 keV.
Thermal analysis of the WFI on the ATHENA observatory
NASA Astrophysics Data System (ADS)
Fürmetz, Maria; Pietschner, Daniel; Meidinger, Norbert
2016-07-01
The WFI (Wide-Field Imager) instrument is one of two instruments of the ATHENA (Advanced Telescope for High- ENergy Astrophysics) mission. ATHENA is the second L-class mission in ESA's Cosmic Vision plan with launch in 2028 and will address the science theme "The Hot and Energetic Universe" by measuring hot gas in clusters and groups of galaxies as well as matter flow in black holes. A moveable mirror assembly focusses the X-ray light to the focal plane of the WFI. The instrument consists of two separate detectors, one with a large DEPFET array of 512x512 pixels and one small and fast detector with 64x64 DEPFET pixels and a readout time of only 80 μs. The mirror system will achieve an angular resolution of 5" HEW. The rather large field of view of 40'x40' in combination with rather high power consumption is challenging not only for the thermal control system. DEPFET sensors as well as front-end electronics and electronics boxes have to be cooled, where a completely passive cooling system with radiators and heat pipes is highly favored. In order to reduce the necessary radiator area, three separate cooling chains with three different temperature levels have been foreseen. So only the DEPFET sensors are cooled down to the lowest temperature of about 190K, while the front-end electronics is supposed to be operated between 250K and 290K. The electronics boxes can be operated at room temperature, nevertheless the excess heat has to be removed. After first estimations of heat loads and radiator areas, a more detailed model of the camera head has been used to identify gradients between the cooling interfaces and the components to be cooled. This information is used within phase A1 of the project to further optimize the design of the instrument, e.g. material selection.
NASA Astrophysics Data System (ADS)
Martin, A. A.; Pereira, L.; Ali, S. M.; Pizzol, C. D.; Tellez, C. A.; Favero, P. P.; Santos, L.; da Silva, V. V.; Praes, C. E. O.
2016-03-01
The aging process involves the reduction in the production of the major components of skin tissue. During intrinsic aging and photoaging processes, in dermis of human skin, fibroblasts become senescent and have decreased activity, which produce low levels of collagen. Moreover, there is accumulation of advanced glycation end products (AGEs). AGEs have incidence in the progression of age-related diseases, principally in diabetes mellitus and in Alzheimer's diseases. AGEs causes intracellular damage and/or apoptosis leading to an increase of the free radicals, generating a crosslink with skin proteins and oxidative stress. The aim of this study is to detect AGEs markers on human skin by in vivo Confocal Raman spectroscopy. Spectra were obtained by using a Rivers Diagnostic System, 785 nm laser excitation and a CCD detector from the skin surface down to 120 μm depth. We analyzed the confocal Raman spectra of the skin dermis of 30 women volunteers divided into 3 groups: 10 volunteers with diabetes mellitus type II, 65-80 years old (DEW); 10 young healthy women, 20-33 years old (HYW); and 10 elderly healthy women, 65-80 years old (HEW). Pentosidine and glucosepane were the principally identified AGEs in the hydroxyproline and proline Raman spectral region (1000-800 cm-1), in the 1.260-1.320 cm-1 region assignable to alpha-helical amide III modes, and in the Amide I region. Pentosidine and glucosepane calculated vibrational spectra were performed through Density Functional Theory using the B3LYP functional with 3-21G basis set. Difference between the Raman spectra of diabetic elderly women and healthy young women, and between healthy elderly women and healthy young women were also obtained with the purpose of identifying AGEs Raman bands markers. AGEs peaks and collagen changes have been identified and used to quantify the glycation process in human skin.
NASA Astrophysics Data System (ADS)
Arcangeli, L.; Borghi, G.; Bräuninger, H.; Citterio, O.; Ferrario, I.; Friedrich, P.; Grisoni, G.; Marioni, F.; Predehl, P.; Rossi, M.; Ritucci, A.; Valsecchi, G.; Vernani, D.
2017-11-01
The name "eROSITA" stands for extended Roentgen Survey with an Imaging Telescope Array. The general design of the eROSITA X-ray telescope is derived from that of ABRIXAS. A bundle of 7 mirror modules with short focal lengths make up a compact telescope which is ideal for survey observations. Similar designs had been proposed for the missions DUO and ROSITA but were not realized due to programmatic shortfall. Compared to those, however, the effective area in the soft X-ray band has now much increased by adding 27 additional outer mirror shells to the original 27 ones of each mirror module. The requirement on the on-axis resolution has also been confined, namely to 15 arc seconds HEW. For these reasons the prefix "extended" was added to the original name "ROSITA". The scientific motivation for this extension is founded in the ambitious goal to detect about 100,000 clusters of galaxies which trace the large scale structure of the Universe in space and time. The X-ray telescope of eROSITA will consist of 7 identical and co-aligned mirror modules, each with 54 nested Wolter-1 mirror shells. The mirror shells are glued onto a spider wheel which is screwed to the mirror interface structure making a rigid mechanical unit. The assembly of 7 modules forms a compact hexagonal configuration with 1300 mm diameter (see Fig. 1) and will be attached to the telescope structure which connects to the 7 separate CCD cameras in the focal planes. The co-alignment of the mirror module enables eROSITA to perform also pointed observations. The replication process described in chapter III allows the manufacturing in one single piece and at the same time of both the parabola and hyperbola parts of the Wolter 1 mirror.
Sheth, Bhavin R.; Young, Ryan
2016-01-01
Evidence is strong that the visual pathway is segregated into two distinct streams—ventral and dorsal. Two proposals theorize that the pathways are segregated in function: The ventral stream processes information about object identity, whereas the dorsal stream, according to one model, processes information about either object location, and according to another, is responsible in executing movements under visual control. The models are influential; however recent experimental evidence challenges them, e.g., the ventral stream is not solely responsible for object recognition; conversely, its function is not strictly limited to object vision; the dorsal stream is not responsible by itself for spatial vision or visuomotor control; conversely, its function extends beyond vision or visuomotor control. In their place, we suggest a robust dichotomy consisting of a ventral stream selectively sampling high-resolution/focal spaces, and a dorsal stream sampling nearly all of space with reduced foveal bias. The proposal hews closely to the theme of embodied cognition: Function arises as a consequence of an extant sensory underpinning. A continuous, not sharp, segregation based on function emerges, and carries with it an undercurrent of an exploitation-exploration dichotomy. Under this interpretation, cells of the ventral stream, which individually have more punctate receptive fields that generally include the fovea or parafovea, provide detailed information about object shapes and features and lead to the systematic exploitation of said information; cells of the dorsal stream, which individually have large receptive fields, contribute to visuospatial perception, provide information about the presence/absence of salient objects and their locations for novel exploration and subsequent exploitation by the ventral stream or, under certain conditions, the dorsal stream. We leverage the dichotomy to unify neuropsychological cases under a common umbrella, account for the increased prevalence of multisensory integration in the dorsal stream under a Bayesian framework, predict conditions under which object recognition utilizes the ventral or dorsal stream, and explain why cells of the dorsal stream drive sensorimotor control and motion processing and have poorer feature selectivity. Finally, the model speculates on a dynamic interaction between the two streams that underscores a unified, seamless perception. Existing theories are subsumed under our proposal. PMID:27920670
Sheth, Bhavin R; Young, Ryan
2016-01-01
Evidence is strong that the visual pathway is segregated into two distinct streams-ventral and dorsal. Two proposals theorize that the pathways are segregated in function: The ventral stream processes information about object identity, whereas the dorsal stream, according to one model, processes information about either object location, and according to another, is responsible in executing movements under visual control. The models are influential; however recent experimental evidence challenges them, e.g., the ventral stream is not solely responsible for object recognition; conversely, its function is not strictly limited to object vision; the dorsal stream is not responsible by itself for spatial vision or visuomotor control; conversely, its function extends beyond vision or visuomotor control. In their place, we suggest a robust dichotomy consisting of a ventral stream selectively sampling high-resolution/ focal spaces, and a dorsal stream sampling nearly all of space with reduced foveal bias. The proposal hews closely to the theme of embodied cognition: Function arises as a consequence of an extant sensory underpinning. A continuous, not sharp, segregation based on function emerges, and carries with it an undercurrent of an exploitation-exploration dichotomy. Under this interpretation, cells of the ventral stream, which individually have more punctate receptive fields that generally include the fovea or parafovea, provide detailed information about object shapes and features and lead to the systematic exploitation of said information; cells of the dorsal stream, which individually have large receptive fields, contribute to visuospatial perception, provide information about the presence/absence of salient objects and their locations for novel exploration and subsequent exploitation by the ventral stream or, under certain conditions, the dorsal stream. We leverage the dichotomy to unify neuropsychological cases under a common umbrella, account for the increased prevalence of multisensory integration in the dorsal stream under a Bayesian framework, predict conditions under which object recognition utilizes the ventral or dorsal stream, and explain why cells of the dorsal stream drive sensorimotor control and motion processing and have poorer feature selectivity. Finally, the model speculates on a dynamic interaction between the two streams that underscores a unified, seamless perception. Existing theories are subsumed under our proposal.
Comportamiento del Helio en estrellas químicamente peculiares
NASA Astrophysics Data System (ADS)
Malaroda, S. M.; López García, Z.; Leone, F.; Catalano, F.
Las estrellas químicamente peculiares (CP) se caracterizan por tener deficiencias y sobreabundancias de algunos elementos químicos de hasta 106 veces la abundancia solar. Además presentan variaciones en las líneas espectrales. Se piensa que ello se debe a que los campos magnéticos presentes en este tipo de estrellas son principalmente dipolares, con un eje de simetría diferente del eje de rotación. La distribución de los elementos sobreabundantes y deficientes no es homogénea sobre la superficie estelar y las variaciones observadas serían una consecuencia directa de la rotación estelar. Entre los elementos con abundancia anómala se encuentra el Helio, cuyas líneas tienen intensidades que no son consistentes con una abundancia normal, que no puede ser determinada del modo usual, o sea, considerando una atmósfera con composición solar. Con el fin de determinar la abundancia de este elemento, se inició un estudio de estrellas anómalas de Helio, Hew y He strong. Además se determinarán las abundancias de otros elementos anómalos como ser el Si, Cr, Mg, Mn y Fe. Las mismas se determinan del modo tradicional, o sea: a) medida de los anchos equivalentes de las líneas de los distintos elementos analizados; b) adopción de la temperatura efectiva, gravedad y abundancia del Helio; c) cálculo del modelo de atmósfera d) comparación con las observaciones y reinicio de un proceso iterativo hasta lograr un acuerdo entre todos los parámetros analizados. Las observaciones se llevaron a cabo en el Complejo Astronómico El Leoncito. Se observaron setenta y ocho estrellas anómalas de Helio. En este momento se está procediendo a calcular las abundancias correspondientes a los distintos elementos químicos. Para ello se hace uso de los modelos de Kurucz, ATLAS9. Los cálculos NLTE de las líneas de Helio se llevan a cabo con el programa MULTI y se compararán con los realizados con el programa WIDTH9 de Kurucz (LTE), con el objeto de resaltar la importancia de los efectos NLTE.
Kishitani, Toru; Matsunaga, Akiko; Ikawa, Masamichi; Hayashi, Kouji; Yamamura, Osamu; Hamano, Tadanori; Watanabe, Osamu; Tanaka, Keiko; Nakamoto, Yasunari; Yoneda, Makoto
2017-03-01
Several types of autoantibodies have been reported in autoimmune limbic encephalitis (LE), such as antibodies against the voltage-gated potassium channel (VGKC) complex including leucine-rich glioma inactivated 1 (LGI1). We recently reported a patient with autoimmune LE and serum anti-NH2-terminal of α-enolase (NAE) antibodies, a specific diagnostic marker for Hashimoto encephalopathy (HE), who was diagnosed with HE based on the presence of antithyroid antibodies and responsiveness to immunotherapy. This case suggests that LE patients with antibodies to both the thyroid and NAE could be diagnosed with HE and respond to immunotherapy. The aim of this study was to clarify the clinicoimmunological features and efficacy of immunotherapy in LE associated with anti-NAE antibodies to determine whether the LE is a clinical subtype of HE.We examined serum anti-NAE antibodies in 78 LE patients with limbic abnormality on magnetic resonance imaging and suspected HE based on positivity for antithyroid antibodies. Nineteen of the 78 patients had anti-NAE antibodies; however, 5 were excluded because they were double positive for antibodies to the VGKC complex including LGI1. No antibodies against the N-methyl-D-aspartate receptor (NMDAR), contactin-associated protein 2 (Caspr2), γ-aminobutyric acid-B receptor (GABABR), or α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor (AMPAR) were detected in the 19 patients. Among the remaining 14 who were positive only for anti-NAE antibodies, the median age was 62.5 (20-83) years, 9 (64%) were women, and 8 (57%) showed acute onset, with less than 2 weeks between onset and admission. Consciousness disturbance (71%) and memory disturbance (64%) were frequently observed, followed by psychiatric symptoms (50%) and seizures (43%). The frequency of these symptoms significantly differed between the acute- and subacute-onset groups. Abnormalities in cerebrospinal fluid and electroencephalogram were commonly observed (92% for both). Tumors were not identified in any cases. All patients responded to immunotherapy or spontaneously remitted, thereby fulfilling the criteria of HE.This study demonstrated that LE associated with anti-NAE antibodies is a nonparaneoplastic LE and various limbic symptoms that depend on the onset type. Favorable therapeutic efficacy suggests that this LE can be considered a clinical subtype of HE and that anti-NAE antibodies may be a promising indicator of the need for immunotherapy.
Breton, Carrie V.; Marsit, Carmen J.; Faustman, Elaine; Nadeau, Kari; Goodrich, Jaclyn M.; Dolinoy, Dana C.; Herbstman, Julie; Holland, Nina; LaSalle, Janine M.; Schmidt, Rebecca; Yousefi, Paul; Perera, Frederica; Joubert, Bonnie R.; Wiemels, Joseph; Taylor, Michele; Yang, Ivana V.; Chen, Rui; Hew, Kinjal M.; Freeland, Deborah M. Hussey; Miller, Rachel; Murphy, Susan K.
2017-01-01
Background: Characterization of the epigenome is a primary interest for children’s environmental health researchers studying the environmental influences on human populations, particularly those studying the role of pregnancy and early-life exposures on later-in-life health outcomes. Objectives: Our objective was to consider the state of the science in environmental epigenetics research and to focus on DNA methylation and the collective observations of many studies being conducted within the Children’s Environmental Health and Disease Prevention Research Centers, as they relate to the Developmental Origins of Health and Disease (DOHaD) hypothesis. Methods: We address the current laboratory and statistical tools available for epigenetic analyses, discuss methods for validation and interpretation of findings, particularly when magnitudes of effect are small, question the functional relevance of findings, and discuss the future for environmental epigenetics research. Discussion: A common finding in environmental epigenetic studies is the small-magnitude epigenetic effect sizes that result from such exposures. Although it is reasonable and necessary that we question the relevance of such small effects, we present examples in which small effects persist and have been replicated across populations and across time. We encourage a critical discourse on the interpretation of such small changes and further research on their functional relevance for children’s health. Conclusion: The dynamic nature of the epigenome will require an emphasis on future longitudinal studies in which the epigenome is profiled over time, over changing environmental exposures, and over generations to better understand the multiple ways in which the epigenome may respond to environmental stimuli. Citation: Breton CV, Marsit CJ, Faustman E, Nadeau K, Goodrich JM, Dolinoy DC, Herbstman J, Holland N, LaSalle JM, Schmidt R, Yousefi P, Perera F, Joubert BR, Wiemels J, Taylor M, Yang IV, Chen R, Hew KM, Freeland DM, Miller R, Murphy SK. 2017. Small-magnitude effect sizes in epigenetic end points are important in children’s environmental health studies: the Children’s Environmental Health and Disease Prevention Research Center’s Epigenetics Working Group. Environ Health Perspect 125:–526; http://dx.doi.org/10.1289/EHP595 PMID:28362264
NASA Astrophysics Data System (ADS)
Tourre, Y. M.; Jarlan, L.; Lacaux, J.-P.; Rotela, C. H.; Lafaye, M.
2008-10-01
Climate-environment variability affects the rates of incidence of vector-borne and zoonotic diseases and is possibly associated with epidemics outbreaks. Over southernmost South America the joint spatio-temporal evolution of climate-environment is analyzed for the 1982-2004 period. Detailed mapping of normalized difference vegetation index (NDVI) and rainfall variability are then compared to zones with preliminary epidemiological reports. A significant quasi-biennial signal (2.2- to 2.4-year periods, or QB) for joint NDVI-rainfall variability is revealed. From rotated EOFs, dominant NDVI patterns are partitioned according to their lead frequencies: (1) the 'QB group' (2.1-to 3-year periods) includes six modes over southern Brazil, Uruguay, northern-central Argentina (two modes), the southern Paraguay-northern Argentina border, and the Santa Cruz Province; (2) the QB1 (2.4- to 3-year periods) + quasi-quadrennial (QQ) mode over the Misiones Province; and (3) the QB2 (2.1- to 2.5-year periods) + QQ + inter-annual (IA) (3- to 7-year periods) two modes over south-eastern Argentina. Modes within the 'QB group' are positively correlated with global climate signals and SST. The Uruguayan mode is correlated with global ENSO (8-month lag) whilst the southern Entre-Rios/northern Buenos Aires provinces are correlated with central equatorial Pacific SSTs (3-month lag). The Santa Cruz (Patagonia) Province is most correlated with the Pacific South America (PSA) index and SST patterns (3-month lag) along the Antarctica circumpolar current. The spatial distribution of lead NDVI modes includes the Formosa, Misiones, Chaco and Buenos Aires provinces among others, known for being prone to vector-borne epidemics such as dengue fever, malaria, leishmaniasis (American cutaneous leishmaniasis or ACL), hantivirus, chagas and Argentine hemorrhagic fever (AHF). Some provinces also correspond to regions where lead NDVI PCs' modes are associated with high-frequency climate signals such as the quasi-biennial oscillation in northwest Argentina. The joint preliminary results (climate-environment-public health reports) presented here for the first time are meant: (1) to contribute to a better understanding of climate-environment-epidemics process-based and modeling studies and (2) to facilitate, in the long run, the implementation of local and regional health early warning systems (HEWS) over southernmost South America. The latter is becoming crucial with ever-increasing migration, urban sprawl (re-emergence of dengue fever epidemics since the late 1990s), all embedded in a climate change context.
Nefdt, Rory; Ribaira, Eric; Diallo, Khassoum
2014-10-01
To ensure correct and appropriate funding is available, there is a need to estimate resource needs for improved planning and implementation of integrated Community Case Management (iCCM). To compare and estimate costs for commodity and human resource needs for iCCM, based on treatment coverage rates, bottlenecks and national targets in Ethiopia, Kenya and Zambia from 2014 to 2016. Resource needs were estimated using Ministry of Health (MoH) targets fronm 2014 to 2016 for implementation of case management of pneumonia, diarrhea and malaria through iCCM based on epidemiological, demographic, economic, intervention coverage and other health system parameters. Bottleneck analysis adjusted cost estimates against system barriers. Ethiopia, Kenya and Zambia were chosen to compare differences in iCCM costs in different programmatic implementation landscapes. Coverage treatment rates through iCCM are lowest in Ethiopia, followed by Kenya and Zambia, but Ethiopia had the greatest increases between 2009 and 2012. Deployment of health extension workers (HEWs) in Ethiopia is more advanced compared to Kenya and Zambia, which have fewer equivalent cadres (called commu- nity health workers (CHWs)) covering a smaller proportion of the population. Between 2014 and 2016, the propor- tion of treatments through iCCM compared to health centres are set to increase from 30% to 81% in Ethiopia, 1% to 18% in Kenya and 3% to 22% in Zambia. The total estimated cost of iCCM for these three years are USD 75,531,376 for Ethiopia, USD 19,839,780 for Kenya and USD 33,667,742 for Zambia. Projected per capita expen- diture for 2016 is USD 0.28 for Ethiopia, USD 0.20 in Kenya and USD 0.98 in Zambia. Commodity costs for pneumonia and diarrhea were a small fraction of the total iCCM budget for all three countries (less than 3%), while around 80% of the costs related to human resources. Analysis of coverage, demography and epidemiology data improves estimates of fimding requirements for iCCM. Bottleneck analysis adjusts cost estimates by including system barriers, thus reflecting a more accurate estimate of potential resource utilization. Adding pneumonia and diarrhea interventions to existing large scale community-based malaria case management programs is likely to require relatively small and nationally affordable investments. iCCM can be implemented for USD 0.09 to 0.98 per capita per annum, depending on the stage of scale-up and targets set by the MoH.
Heritage stones and their deterioration in rock-cut monuments in India
NASA Astrophysics Data System (ADS)
Sharma, Vinod K.
2017-04-01
India is dotted with thousands of rock- cut monuments of considerable antiquity having artwork of global importance. It is evident from the location of many of these monuments that knowledge of viable selection of site, geotechnical considerations and amenability to sculptures' chisel was vital for construction of rock-cut monuments and sculptures. These rock-cut structures also represent significant achievements of geotechnical and structural engineering and craftsmanship of contemporary period. The paper deals with some of the sites where natural rock-mass exposures were used to hew the monuments and highlight the deterioration owing to geological and climatic conditions. The Kailash temple in Ellora and Ajanta rock-cut caves are among the greatest architectural feats which owe their grandeur to amenability and consistency of basalt of Deccan Volcanic Province from which it is hewn. The Kailash Temple was created through a single, huge top-down excavation 100 feet deep down into the volcanic basaltic cliff rock. These ancient rock cut structures are amazing achievements of structural engineering and craftsmanship. The lava flows are nearly horizontal, competent rock medium facilitated the chiseling for the sculptures. The deterioration of these basalts are seen where the amygdule, vesicles and opening in rock discontinuity had the medium of construction or excavation. The monolithic rock- cut monuments of Mahabalipuram temples are constructed in the form of rathas or chriot and adjoining caves by excavating solid charnockite/granites. The large rock exposures are excavated and cut to perfection with wall decorations and sculptured art. The charnockites are the strongest and the most durable rock, yet quite amenable to fine dressing. These monolithic monuments in charnockite and are cut out of the hillock. The 7th Century monuments now exhibit somewhat rough surface probably due to weathering effect of salt laden winds from the sea side and alteration of feldspars. The Rock shelters of Bhimbetka, a World Heritage Site, are located within Vindhyan sandstone, yielded primitive tools and decorative rock paintings.The rock-cut caves in twin hills Udayagiri and Khandagiri , contain carvings sculptured in coarse grained grey to buff coloured sandstone of Gondwana group of rocks. The Badami cave temples constructed out of escarpment of the hill in sandstone represent some of the earliest known examples of Hindu temples. Utilizing in situ rock exposures, natural rocks and landscape of Deccan basalts, granites of peninsular shield, sandstones and limestone for rock cut architecture in India, thus, holds varied examples of rock-cut architectures.
XIPE the X-Ray Imaging Polarimetry Explorer
NASA Technical Reports Server (NTRS)
Soffitta, Paolo; Barcons, Xavier; Bellazzini, Ronaldo; Braga, Joao; Costa, Enrico; Fraser, George W.; Gburek, Szymon; Huovelin, Juhani; Matt, Giorgio; Pearce, Mark;
2013-01-01
X-ray polarimetry, sometimes alone, and sometimes coupled to spectral and temporal variability measurements and to imaging, allows a wealth of physical phenomena in astrophysics to be studied. X-ray polarimetry investigates the acceleration process, for example, including those typical of magnetic reconnection in solar flares, but also emission in the strong magnetic fields of neutron stars and white dwarfs. It detects scattering in asymmetric structures such as accretion disks and columns, and in the so-called molecular torus and ionization cones. In addition, it allows fundamental physics in regimes of gravity and of magnetic field intensity not accessible to experiments on the Earth to be probed. Finally, models that describe fundamental interactions (e.g. quantum gravity and the extension of the Standard Model) can be tested. We describe in this paper the X-ray Imaging Polarimetry Explorer (XIPE), proposed in June 2012 to the first ESA call for a small mission with a launch in 2017. The proposal was, unfortunately, not selected. To be compliant with this schedule, we designed the payload mostly with existing items. The XIPE proposal takes advantage of the completed phase A of POLARIX for an ASI small mission program that was cancelled, but is different in many aspects: the detectors, the presence of a solar flare polarimeter and photometer and the use of a light platform derived by a mass production for a cluster of satellites. XIPE is composed of two out of the three existing JET-X telescopes with two Gas Pixel Detectors (GPD) filled with a He-DME mixture at their focus. Two additional GPDs filled with a 3-bar Ar-DME mixture always face the Sun to detect polarization from solar flares. The Minimum Detectable Polarization of a 1 mCrab source reaches 14 in the 210 keV band in 105 s for pointed observations, and 0.6 for an X10 class solar flare in the 1535 keV energy band. The imaging capability is 24 arcsec Half Energy Width (HEW) in a Field of View of 14.7 arcmin 14.7 arcmin. The spectral resolution is 20 at 6 keV and the time resolution is 8 s. The imaging capabilities of the JET-X optics and of the GPD have been demonstrated by a recent calibration campaign at PANTER X-ray test facility of the Max-Planck-Institut fr extraterrestrische Physik (MPE, Germany). XIPE takes advantage of a low-earth equatorial orbit with Malindi as down-link station and of a Mission Operation Center (MOC) at INPE (Brazil). The data policy is organized with a Core Program that comprises three months of Science Verification Phase and 25 of net observing time in the following 2 years. A competitive Guest Observer program covers the remaining 75 of the net observing time.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of... Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 2 2012-01-01 2012-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of... Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 2 2012-01-01 2012-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of... Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade...
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 2 2011-01-01 2011-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of... Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade...
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 2 2011-01-01 2011-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of... Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade...
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of... Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade...
Bautista-Arredondo, Sergio; Sosa-Rubí, Sandra G.; Opuni, Marjorie; Contreras-Loya, David; Kwan, Ada; Chaumont, Claire; Chompolola, Abson; Condo, Jeanine; Galárraga, Omar; Martinson, Neil; Masiye, Felix; Nsanzimana, Sabin; Ochoa-Moreno, Ivan; Wamai, Richard; Wang’ombe, Joseph
2016-01-01
Objective: We estimate facility-level average annual costs per client along the HIV testing and counselling (HTC) and prevention of mother-to-child transmission (PMTCT) service cascades. Design: Data collected covered the period 2011–2012 in 230 HTC and 212 PMTCT facilities in Kenya, Rwanda, South Africa, and Zambia. Methods: Input quantities and unit prices were collected, as were output data. Annual economic costs were estimated from the service providers’ perspective using micro-costing. Average annual costs per client in 2013 United States dollars (US$) were estimated along the service cascades. Results: For HTC, average cost per client tested ranged from US$5 (SD US$7) in Rwanda to US$31 (SD US$24) in South Africa, whereas average cost per client diagnosed as HIV-positive ranged from US$122 (SD US$119) in Zambia to US$1367 (SD US$2093) in Rwanda. For PMTCT, average cost per client tested ranged from US$18 (SD US$20) in Rwanda to US$89 (SD US$56) in South Africa; average cost per client diagnosed as HIV-positive ranged from US$567 (SD US$417) in Zambia to US$2021 (SD US$3210) in Rwanda; average cost per client on antiretroviral prophylaxis ranged from US$704 (SD US$610) in South Africa to US$2314 (SD US$3204) in Rwanda; and average cost per infant on nevirapine ranged from US$888 (SD US$884) in South Africa to US$2359 (SD US$3257) in Rwanda. Conclusion: We found important differences in unit costs along the HTC and PMTCT service cascades within and between countries suggesting that more efficient delivery of these services is possible. PMID:27753679
Interagency Evaluation of the Section 1206 Global Train and Equip Program
2009-08-31
Capabilities, Joint Staff, U.S. Africa Command, U.S. Central Command, U.S Joint Forces Command, U.S. Pacific Command, U.S. Southern Command, U.S. Special...Intensity Conflict & Interdependent Capabilities; Commanders of U.S. Africa Command, U.S. Central Command, U.S. Joint Forces Command, U.S. Pacific... Central Command, commented that coordinating the Section 1206 project proposal with the partner nation prior to submission would inflate the
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 2 2013-01-01 2013-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U...
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 2 2014-01-01 2014-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U...
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 2 2014-01-01 2014-01-01 false U.S. Grade B Small; U.S. Grade B Medium; U.S. Grade B Medium to Large; U.S. Grade B Large. 51.1576 Section 51.1576 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1576 U.S. Grade B Small; U.S. Grade B Medium; U...
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 2 2013-01-01 2013-01-01 false U.S. Grade A Small; U.S. Grade A Medium; U.S. Grade A Medium to Large; U.S. Grade A Large. 51.1575 Section 51.1575 Agriculture Regulations of the Department of...) United States Consumer Standards for Potatoes Grades § 51.1575 U.S. Grade A Small; U.S. Grade A Medium; U...
Health care costs in US patients with and without a diagnosis of osteoarthritis
Le, T Kim; Montejano, Leslie B; Cao, Zhun; Zhao, Yang; Ang, Dennis
2012-01-01
Background Osteoarthritis is a chronic and costly condition affecting 14% of adults in the US, and has a significant impact on patient quality of life. This retrospective cohort study compared direct health care utilization and costs between patients with osteoarthritis and a matched control group without osteoarthritis. Methods MarketScan® databases were used to identify adult patients with an osteoarthritis claim (ICD-9-CM, 715.xx) in 2007, and the date of first diagnosis served as the index. Patients were excluded if they did not have 12 months of continuous health care benefit prior to and following the index date, were aged <18 years, or lacked a second diagnosis code for osteoarthritis between 15 and 365 days pre-index or post-index. Osteoarthritis patients were matched 1:1 to patients without osteoarthritis for age group, gender, geographic region, health plan type, and Medicare eligibility. Multivariate analyses were conducted to assess for differences in utilization and costs, controlling for differences between cohorts. Results The study sample included 258,237 patients with osteoarthritis and 258,237 matched controls without osteoarthritis. Most patients were women and over 55 years of age. Patients with osteoarthritis had significantly higher pre-index rates of comorbidity than controls. Mean total adjusted direct costs for osteoarthritis patients were more than double those for the control group at US$18,435 (95% confidence interval [CI]: US$18,318–US$18,560) versus US$7494 (95% CI: US$7425–US$7557). Osteoarthritis patients incurred significantly higher inpatient costs at US$6668 (95% CI: US$6587–US$6744) versus US$1756 (95% CI: US$1717–US$1794), outpatient costs at US$7840 (95% CI: US$7786–US$7902) versus US$3675 (95% CI: US$3637–US$3711), and prescription drug costs at US$3213 (95% CI: US$3195–US$3233) versus US$2245 (95% CI: US$2229–US$2262) compared with the controls. Conclusion The direct health care costs of osteoarthritis patients were over two times higher than those of similar patients without the condition. The primary drivers of the cost difference were comorbidities and inpatient costs. PMID:22328832
NREL: U.S. Life Cycle Inventory Database - Stakeholders
Sylvatica U.S. Car Project (Ford, General Motors, and DaimlerChrysler) U.S. Department of Agriculture U.S Agriculture, Forest Service R&D U.S. Department of Energy U.S. Environmental Protection Agency U.S
23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes
Code of Federal Regulations, 2011 CFR
2011-04-01
... Anchorage AK 3 Palmer. AK 2 AK 3 Fairbanks Milepost 1412 Delta Junction. AK 3 AK 1 Palmer AK 2 Fairbanks... Harbors. US 63 I-90 Rochester US 52 Rochester. US 63 MN 58 Red Wing WI State Line. US 71 IA State Line MN... State Line Red Wing MN US 2 W. of Ashland. US 141 US 41 Abrams US 8 Pembine. US 151 IA State Line...
23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes
Code of Federal Regulations, 2010 CFR
2010-04-01
... Anchorage AK 3 Palmer. AK 2 AK 3 Fairbanks Milepost 1412 Delta Junction. AK 3 AK 1 Palmer AK 2 Fairbanks... Harbors. US 63 I-90 Rochester US 52 Rochester. US 63 MN 58 Red Wing WI State Line. US 71 IA State Line MN... State Line Red Wing MN US 2 W. of Ashland. US 141 US 41 Abrams US 8 Pembine. US 151 IA State Line...
U.S. Korean Youth's Ideas and Experience of U.S. Education, U.S. Society, and U.S. History
ERIC Educational Resources Information Center
An, Sohyun
2009-01-01
Drawing on and conversing with the large body of research and literature on young people's historical understanding, Asian American education, transnational migration, and Korean American studies, this dissertation research explored contemporary U.S. Korean youth's ideas and experiences of U.S. education, U.S. society and U.S. history.…
Fermilab Friends for Science Education | Join Us
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77 FR 60603 - National Arts and Humanities Month, 2012
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-04
... given us comfort and confidence, drawn us together, and called on us to strive for a more perfect Union... can resonate with us, challenge us, and teach us important lessons about ourselves and each other. At... all of us. They open dialogues between cultures and raise poignant questions about our world. They are...
Naval History Contact Us Command Addresses (SNDL) FAQ Leadership Secretary of the Navy Under Secretary Chiefs of Staff Defense.gov U.S. Army U.S. Air Force U.S. Marine Corps U.S. Coast Guard Naval History https://awards.navy.mil Naval Heritage And History Command http://www.history.navy.mil/about-us
Gu, Wei Xiang; Tan, Chuen Seng; Ho, Thomas W T
2014-06-01
Ultrasound-guided fine-needle aspiration cytology (US-FNAC) of thyroid nodules is an important diagnostic procedure. In most hospitals, patients are referred to radiologists for US-FNAC, but this often results in a long waiting time before results are available. Surgeon-performed US-FNAC (SP-US-FNAC) during the initial patient consultation attempts to reduce the waiting time but it is not known whether this is as accurate as radiologist-performed US-FNAC (RP-US-FNAC). The aim of this study is to compare the clinical efficiency between SP-US-FNAC and RP-US-FNAC. A retrospective study was performed on patients from the Department of General Surgery, Tan Tock Seng Hospital (TTSH) who underwent an US-FNAC from August 2011 to May 2012. All cases of SP-US-FNAC were performed by a single surgeon. This study compared the rates of positive diagnoses achieved by SP-US-FNAC and RPUS- FNAC as well as the time interval to reach a cytological diagnosis by each group. A total of 40 cases of SP-US-FNAC and 72 cases of RP-US-FNAC were included in the study. SP-US-FNAC resulted in 28 (70%) positive diagnoses and 12 (30%) nondiagnoses while RP-US-FNAC resulted in 47 (65.3%) positive diagnoses and 25 (34.7%) non-diagnoses. These results were comparable (P=0.678). The median time taken to reach a cytological diagnosis was 1 working day for SP-US-FNAC and 29.5 working days for RP-US-FNAC resulting in a shorter interval to reaching a cytological diagnosis for SP-US-FNAC (P<0.001). In the workup of thyroid nodules, SP-US-FNAC is as accurate as RP-US-FNAC but significantly reduces the time taken to reach a cytological diagnosis. This leads to greater clinical efficiency in the management of patients with thyroid nodules, which in turn leads to other benefits such as decreased patient anxiety and increased patient satisfaction.
Yang, Tsong-Shing; Chi, Ching-Chi; Wang, Shu-Hui; Lin, Jing-Chi; Lin, Ko-Ming
2016-10-01
Biologic therapies are more effective but more costly than conventional therapies in treating psoriatic arthritis. To evaluate the cost-efficacy of etanercept, adalimumab and golimumab therapies in treating active psoriatic arthritis in a Taiwanese setting. We conducted a meta-analysis of randomized placebo-controlled trials to calculate the incremental efficacy of etanercept, adalimumab and golimumab, respectively, in achieving Psoriatic Arthritis Response Criteria (PsARC) and a 20% improvement in the American College of Rheumatology score (ACR20). The base, best, and worst case incremental cost-effectiveness ratios (ICERs) for one subject to achieve PsARC and ACR20 were calculated. The annual ICER per PsARC responder were US$27 047 (best scenario US$16 619; worst scenario US$31 350), US$39 339 (best scenario US$31 846; worst scenario US$53 501) and US$27 085 (best scenario US$22 716; worst scenario US$33 534) for etanercept, adalimumab and golimumab, respectively. The annual ICER per ACR20 responder were US$27 588 (best scenario US$20 900; worst scenario US$41 800), US$39 339 (best scenario US$25 236; worst scenario US$83 595) and US$33 534 (best scenario US$27 616; worst scenario US$44 013) for etanercept, adalimumab and golimumab, respectively. In a Taiwanese setting, etanercept had the lowest annual costs per PsARC and ACR20 responder, while adalimumab had the highest annual costs per PsARC and ACR responder. © 2015 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.
‘US Furr’ and ‘US Furr-ST’ Mandarin
USDA-ARS?s Scientific Manuscript database
This document marks the official release of ‘US Furr’, a hybrid of ‘Clementine’ x ‘Murcott’, and ‘US Furr-ST’, an irradiated variant of ‘US Furr’ with apparent field tolerance to citrus scab (causal agent Elsinoe fawcetti Bitanc. and Jenk.). The hybridization creating ‘US Furr’ and ultimately ‘US Fu...
Ultrasound guidance system for prostate biopsy
NASA Astrophysics Data System (ADS)
Hummel, Johann; Kerschner, Reinhard; Kaar, Marcus; Birkfellner, Wolfgang; Figl, Michael
2017-03-01
We designed a guidance system for prostate biopsy based on PET/MR images and 3D ultrasound (US). With our proposed method common inter-modal MR-US (or CT-US in case of PET/CTs) registration can be replaced by an intra-modal 3D/3D-US/US registration and an optical tracking system (OTS). On the pre-operative site, a PET/MR calibration allows to link both hybrid modalities with an abdominal 3D-US. On the interventional site, another abdominal 3D US is taken to merge the pre-operative images with the real-time 3D-US via 3D/3D-US/US registration. Finally, the images of a tracked trans-rectal US probe can be displayed with the pre-operative images by overlay. For PET/MR image fusion we applied a point-to-point registration between PET and OTS and MR and OTS, respectively. 3D/3D-US/US registration was evaluated for images taken in supine and lateral patient position. To enable table shifts between PET/MR and US image acquisition a table calibration procedure is presented. We found fiducial registration errors of 0.9 mm and 2.8 mm, respectively, with respect to the MR and PET calibration. A target registration error between MR and 3D US amounted to 1.4 mm. The registration error for the 3D/3D-US/US registration was found to be 3.7 mm. Furthermore, we have shown that ultrasound is applicable in an MR environment.
A cost comparison of more and less nutritious food choices in US supermarkets.
Katz, David L; Doughty, Kim; Njike, Valentine; Treu, Judith A; Reynolds, Jesse; Walker, Jennifer; Smith, Erica; Katz, Catherine
2011-09-01
The present study directly compared prices of more and less nutritious foods within given categories in US supermarkets. Foods selected from six supermarkets in Jackson County were categorized using the five criteria of the Nutrition Detectives™ (ND) programme and an item-to-item cost comparison was made using posted prices. The nutritional quality of foods was distinguished using the clues of the ND nutrition education programme for elementary-school children and validated using the Overall Nutritional Quality Index. Supermarkets in Jackson County, MO, USA. Not applicable. The average price of the item for more nutritious foods did not differ significantly from that of less nutritious foods overall ($US 2·89 (sd $US 0·74) v. $US 2·85 (sd $0·68), P = 0·76). More nutritious breads cost more than less nutritious breads ($US 3·36 (sd $ US 0·28) v. $US 2·56 (sd $US 0·80, P = 0·03), whereas more nutritious cereals ($US 2·46 (sd $US 0·69) v. $US 3·50 (sd $US 0·30), P < 0·01) and cookies ($US 2·76 (sd $US 0·50) v. $US 3·40 (sd $US0·28), P < 0·01) cost less. Our findings indicate that it is possible to choose more nutritious foods within many common categories without spending more money and suggest that making small improvements in dietary choices does not invariably cost more.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Authority of U.S. Immigration and Customs.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and.... (b) U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers have the...
The U.S. Navy in the World (2001-2010): Context for U.S. Navy Capstone Strategies and Concepts
2011-12-01
Merchant Marine ocean- going shipbuilding each down to single digits US shipbuilding industry largely dependent on US Navy orders Building few commercial...Merchant Marine ships 228 2000s: US shipbuilding industrial base 115 229 2000s: US government shipbuilding policies No US government ship construction ...Context for U.S. Navy Capstone Strategies and Concepts 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT
A navigation system for flexible endoscopes using abdominal 3D ultrasound
NASA Astrophysics Data System (ADS)
Hoffmann, R.; Kaar, M.; Bathia, Amon; Bathia, Amar; Lampret, A.; Birkfellner, W.; Hummel, J.; Figl, M.
2014-09-01
A navigation system for flexible endoscopes equipped with ultrasound (US) scan heads is presented. In contrast to similar systems, abdominal 3D-US is used for image fusion of the pre-interventional computed tomography (CT) to the endoscopic US. A 3D-US scan, tracked with an optical tracking system (OTS), is taken pre-operatively together with the CT scan. The CT is calibrated using the OTS, providing the transformation from CT to 3D-US. Immediately before intervention a 3D-US tracked with an electromagnetic tracking system (EMTS) is acquired and registered intra-modal to the preoperative 3D-US. The endoscopic US is calibrated using the EMTS and registered to the pre-operative CT by an intra-modal 3D-US/3D-US registration. Phantom studies showed a registration error for the US to CT registration of 5.1 mm ± 2.8 mm. 3D-US/3D-US registration of patient data gave an error of 4.1 mm compared to 2.8 mm with the phantom. From this we estimate an error on patient experiments of 5.6 mm.
Matera, Jakub T; Egerton-Warburton, Diana; Meek, Robert
2010-12-01
To survey Fellows of the Australasian College for Emergency Medicine (FACEMs) in order to describe current ultrasound (US) usage during central venous catheter (CVC) placement and to compare practice and opinions between FACEMs routinely using US and those not. Descriptive and analytical cross-sectional electronic survey of all FACEMs. Baseline variables including hospital type, US availability, frequency of CVC insertion, US usage and technique are presented descriptively. US practice and opinions on usage are compared between routine and non-routine users. Responses were obtained from 486 (42.4%) of 1146 FACEMs emailed. Whereas 88.5% of respondents had US available and 70% had done an US course, only 37% routinely used US for CVC placement. Completion of an US course and performance of >11 CVC per year were strongly associated with routine US use (odds ratio 10.0 [5.5-18.4] and 2.6 [1.7-3.9], respectively). Common barriers to more frequent US use were not having completed an US course (20%) and US-guided CVC placement taking too long (18%). Eighty-five per cent of FACEMs agreed that there should be ED access to US and US training but only 34% thought its use should be mandatory. We found that only 37% of FACEM respondents routinely used US to guide placement of CVCs and a number of barriers to more frequent use are identified. Practices and opinions regarding US use differed significantly between routine and non-routine users. © 2010 The Authors. EMA © 2010 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.
The wide field imager instrument for Athena
NASA Astrophysics Data System (ADS)
Meidinger, Norbert; Eder, Josef; Eraerds, Tanja; Nandra, Kirpal; Pietschner, Daniel; Plattner, Markus; Rau, Arne; Strecker, Rafael
2016-07-01
The WFI (Wide Field Imager) instrument is planned to be one of two complementary focal plane cameras on ESA's next X-ray observatory Athena. It combines unprecedented survey power through its large field of view of 40 amin x 40 amin together with excellent count rate capability (>= 1 Crab). The energy resolution of the silicon sensor is state-of-the-art in the energy band of interest from 0.2 keV to 15 keV, e.g. the full width at half maximum of a line at 7 keV will be <= 170 eV until the end of the nominal mission phase. This performance is accomplished by using DEPFET active pixel sensors with a pixel size of 130 μm x 130 μm well suited to the on-axis angular resolution of 5 arcsec half energy width (HEW) of the mirror system. Each DEPFET pixel is a combined sensor-amplifier structure with a MOSFET integrated onto a fully depleted 450 μm thick silicon bulk. Two detectors are planned for the WFI instrument: A large-area detector comprising four sensors with a total of 1024 x 1024 pixels and a fast detector optimized for high count rate observations. This high count rate capable detector permits for bright point sources with an intensity of 1 Crab a throughput of more than 80% and a pile-up of less than 1%. The fast readout of the DEPFET pixel matrices is facilitated by an ASIC development, called VERITAS-2. Together with the Switcher-A, a control ASIC that allows for operation of the DEPFET in rolling shutter mode, these elements form the key components of the WFI detectors. The detectors are surrounded by a graded-Z shield, which has in particular the purpose to avoid fluorescence lines that would contribute to the instrument background. Together with ultra-thin coating of the sensor and particle identification by the detector itself, the particle induced background shall be minimized in order to achieve the scientific requirement of a total instrumental background value smaller than 5 x 10-3 cts/cm2/s/keV. Each detector has its dedicated detector electronics (DE) for supply and data acquisition. Due to the high frame rate in combination with the large pixel array, signal correction and event filtering have to be done on-board and in real-time as the raw data rate would by far exceed the feasible telemetry rate. The data streams are merged and compressed in the Instrument Control and Power distribution Unit (ICPU). The ICPU is the data, control and power interface of the WFI to the Athena spacecraft. The WFI instrument comprises in addition a filter wheel (FW) in front of the camera as well as an optical stray-light baffle. In the current phase A of the Athena project, the technology development is performed. At its end, breadboard models will be developed and tested to demonstrate a technical readiness level (TRL) of at least 5 for the various WFI subsystems before mission adoption in 2020.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Bright, U.S. No. 1, U.S. No. 1 Golden, U.S. No. 1 Bronze, U.S. No. 1 Russet, U.S. No. 2 Bright, U.S. No... standards, means the point of origin of the shipment in the producing area or at port of loading for ship... further, that the entire lot averages within percentage specified. (2) U.S. No. 1 Golden. Not more than 30...
Code of Federal Regulations, 2010 CFR
2010-01-01
..., U.S. No. 1 Bright, U.S. No. 1, U.S. No. 1 Golden, U.S. No. 1 Bronze, U.S. No. 1 Russet, U.S. No. 2... in these standards, means the point of origin of the shipment in the producing area or at port of... specified. (2) U.S. No. 1 Golden. Not more than 30 percent of the fruit shall have in excess of one-third of...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Bright, U.S. No. 1, U.S. No. 1 Golden, U.S. No. 1 Bronze, U.S. No. 1 Russet, U.S. No. 2 Bright, U.S. No... in these standards, means the point of origin of the shipment in the producing area or at port of... specified. (2) U.S. No. 1 Golden. Not more than 30 percent of the fruit shall have in excess of one-third of...
AmeriFlux US-SCw Southern California Climate Gradient - Pinyon/Juniper Woodland
DOE Office of Scientific and Technical Information (OSTI.GOV)
Goulden, Mike
This is the AmeriFlux version of the carbon flux data for the site US-SCw Southern California Climate Gradient - Pinyon/Juniper Woodland. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a Pinyon Juniper woodland with trees that are at least 150 years old, and ephemeral herbaceous cover following winter or spring rains. The site has experienced repeated drought during the record and roughly 50% Pinyon mortality over the last decade. Amore » nearby tower site (US-SCc) burned in a 1994 wildfire; comparisons between US-SCw and US-SCc provide a measure of the effects of the 1994 on land-atmosphere exchange.« less
An, Ruopeng; Wang, Peizhong Peter
2017-01-01
In this study, we examined the length of stay, hospitalization cost, and risk of in-hospital mortality among US adult inpatients with immune thrombocytopenic purpura (ITP). We analyzed nationally representative data obtained from Nationwide/National Inpatient Sample database of discharges from 2006 to 2012. In the US, there were an estimated 296,870 (95% confidence interval [CI]: 284,831-308,909) patient discharges recorded for ITP from 2006 to 2012, during which ITP-related hospitalizations had increased steadily by nearly 30%. The average length of stay for an ITP-related hospitalization was found to be 6.02 days (95% CI: 5.93-6.10), which is 28% higher than that of the overall US discharge population (4.70 days, 95% CI: 4.66-4.74). The average cost of ITP-related hospitalizations was found to be US$16,594 (95% CI: US$16,257-US$16,931), which is 48% higher than that of the overall US discharge population (US$11,200; 95% CI: US$11,033-US$11,368). Gender- and age-adjusted mortality risk in inpatients with ITP was 22% (95% CI: 19%-24%) higher than that of the overall US discharge population. Across diagnosis related groups, length of stay for ITP-related hospitalizations was longest for septicemia (7.97 days, 95% CI: 7.55-8.39) and splenectomy (7.40 days, 95% CI: 6.94-7.86). Splenectomy (US$25,262; 95% CI: US$24,044-US$26,481) and septicemia (US$18,430; 95% CI: US$17,353-US$19,507) were associated with the highest cost of hospitalization. The prevalence of mortality in ITP-related hospitalizations was highest for septicemia (11.11%, 95% CI: 9.60%-12.63%) and intracranial hemorrhage (9.71%, 95% CI: 7.65%-11.77%). Inpatients with ITP had longer hospital stay, bore higher costs, and faced greater risk of mortality than the overall US discharge population.
Prostate ultrasound--for urologists only?
Frauscher, Ferdinand; Gradl, Johann; Pallwein, Leo
2005-11-23
The value of ultrasound (US) in the diagnosis of prostate cancer has dramatically increased in the past decade. This is mainly related to the increasing incidence of prostate cancer, the most common cancer in men and one of the most important causes of death from cancer in men. The value of conventional gray-scale US for prostate cancer detection has been extensively investigated, and has shown a low sensitivity and specificity. Therefore conventional gray-scale US is mainly used by urologists for guiding systematic prostate biopsies. With the development of new US techniques, such as color and power Doppler US, and the introduction of US contrast agents, the role of US for prostate cancer detection has dramatically changed. Advances in US techniques were introduced to further increase the value of US contrast agents. Although most of these developments in US techniques, which use the interaction of the contrast agent with the transmitted US waves, are very sensitive for the detection of microbubbles, they are mostly unexplored, in particular for prostate applications. Early reports of contrast-enhanced US investigations of blood flow of the prostate have shown that contrast-enhanced US adds important information to the conventional gray-scale US technique. Furthermore, elastography or 'strain imaging' seems to have great potential in prostate cancer detection. Since these new advances in US are very sophisticated and need a long learning curve, radiologists, who are overall better trained with these new US techniques, will play a more important role in prostate cancer diagnosis. Current trends show that these new US techniques may allow for targeted biopsies and therefore replace the current 'gold standard' for prostate cancer detection--the systematic biopsy. Consequently the use of these new US techniques for the detection and clinical staging of prostate cancer is promising. However, future clinical trials will be needed to determine if the promise of these new US advances of the prostate evolves into clinical application. International Cancer Imaging Society.
Seidl Johnson, Anna C; Frost, Kenneth E; Rouse, Douglas I; Gevens, Amanda J
2015-04-01
Epidemics of late blight, caused by Phytophthora infestans (Mont.) de Bary, have been studied by plant pathologists and regarded with great concern by potato and tomato growers since the Irish potato famine in the 1840s. P. infestans populations have continued to evolve, with unique clonal lineages arising which differ in pathogen fitness and pathogenicity, potentially impacting epidemiology. In 2012 and 2013, the US-23 clonal lineage predominated late blight epidemics in most U.S. potato and tomato production regions, including Wisconsin. This lineage was unknown prior to 2009. For isolates of three recently identified clonal lineages of P. infestans (US-22, US-23, and US-24), sporulation rates were experimentally determined on potato and tomato foliage and the effect of temperature on lesion growth rate on tomato was investigated. The US-22 and US-23 isolates had greater lesion growth rates on tomato than US-24 isolates. Sporulation rates for all isolates were greater on potato than tomato, and the US-23 isolates had greater sporulation rates on both tomato and potato than the US-22 and US-24 isolates. Experimentally determined correlates of fitness were input to the LATEBLIGHT model and epidemics were simulated using archived Wisconsin weather data from four growing seasons (2009 to 2012) to investigate the effect of isolates of these new lineages on late blight epidemiology. The fast lesion growth rates of US-22 and US-23 isolates resulted in severe epidemics in all years tested, particularly in 2011. The greater sporulation rates of P. infestans on potato resulted in simulated epidemics that progressed faster than epidemics simulated for tomato; the high sporulation rates of US-23 isolates resulted in simulated epidemics more severe than simulated epidemics of isolates of the US-22 and US-24 isolates and EC-1 clonal lineages on potato and tomato. Additionally, US-23 isolates consistently caused severe simulated epidemics when lesion growth rate and sporulation were input into the model singly or together. Sporangial size of the US-23 isolates was significantly smaller than that of US-22 and US-24 isolates, which may result in more efficient release of sporangia from the tomato or potato canopy. Our experimentally determined correlates of fitness and the simulated epidemics resulting from their incorporation into the LATEBLIGHT model suggest that US-23 isolates of P. infestans may have the greatest fitness among currently prevalent lineages and may be the most likely lineage to persist in the P. infestans population. The US-23 clonal lineage has been documented as the most prevalent lineage in recent years, indicating its overall fitness. In our work, US-23 had the highest epidemic potential among current genotypes. Given that epidemic potential is a component of fitness, this may, in part, explain the current predominance of the US-23 lineage.
ERIC Educational Resources Information Center
Capaldi, E. J.; Martins, Ana P. G.; Altman, Meaghan
2009-01-01
arrow]US associations also survived The memories of the unconditioned stimulus (US) and its absence (No US), symbolized as S[superscript R] and S[superscript N], respectively, may be retrieved on US or No US trials giving rise to four types of associations, S[superscript R][right arrow]US, S[superscript R][right arrow]No US, S[superscript N][right…
history of Nino3.4 SST anomalies of individual forecasts Forecast anomalies Target season Nino SST Global SST Global Prec Global T2m US Prec US T2m US SM z200 NDJ 2004/2005 Nino SST Global SST Global Prec Global T2m US Prec US T2m US SM z200 DJF 2005 Nino SST Global SST Global Prec Global T2m US Prec US T2m
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Liu, Tongtong; Ge, Xifeng; Yu, Jinhua; Guo, Yi; Wang, Yuanyuan; Wang, Wenping; Cui, Ligang
2018-06-21
B-mode ultrasound (B-US) and strain elastography ultrasound (SE-US) images have a potential to distinguish thyroid tumor with different lymph node (LN) status. The purpose of our study is to investigate whether the application of multi-modality images including B-US and SE-US can improve the discriminability of thyroid tumor with LN metastasis based on a radiomics approach. Ultrasound (US) images including B-US and SE-US images of 75 papillary thyroid carcinoma (PTC) cases were retrospectively collected. A radiomics approach was developed in this study to estimate LNs status of PTC patients. The approach included image segmentation, quantitative feature extraction, feature selection and classification. Three feature sets were extracted from B-US, SE-US, and multi-modality containing B-US and SE-US. They were used to evaluate the contribution of different modalities. A total of 684 radiomics features have been extracted in our study. We used sparse representation coefficient-based feature selection method with 10-bootstrap to reduce the dimension of feature sets. Support vector machine with leave-one-out cross-validation was used to build the model for estimating LN status. Using features extracted from both B-US and SE-US, the radiomics-based model produced an area under the receiver operating characteristic curve (AUC) [Formula: see text] 0.90, accuracy (ACC) [Formula: see text] 0.85, sensitivity (SENS) [Formula: see text] 0.77 and specificity (SPEC) [Formula: see text] 0.88, which was better than using features extracted from B-US or SE-US separately. Multi-modality images provided more information in radiomics study. Combining use of B-US and SE-US could improve the LN metastasis estimation accuracy for PTC patients.
Genomic organization of the canine herpesvirus US region.
Haanes, E J; Tomlinson, C C
1998-02-01
Canine herpesvirus (CHV) is an alpha-herpesvirus of limited pathogenicity in healthy adult dogs and infectivity of the virus appears to be largely limited to cells of canine origin. CHV's low virulence and species specificity make it an attractive candidate for a recombinant vaccine vector to protect dogs against a variety of pathogens. As part of the analysis of the CHV genome, the authors determined the complete nucleotide sequence of the CHV US region as well as portions of the flanking inverted repeats. Seven full open reading frames (ORFs) encoding proteins larger than 100 amino acids were identified within, or partially within the CHV US: cUS2, cUS3, cUS4, cUS6, cUS7, cUS8 and cUS9; which are homologs of the herpes simplex virus type-1 US2; protein kinase; gG, gD, gI, gE; and US9 genes, respectively. An eighth ORF was identified in the inverted repeat region, cIR6, a homolog of the equine herpesvirus type-1 IR6 gene. The authors identified and mapped most of the major transcripts for the predicted CHV US ORFs by Northern analysis.
Minami, Yasunori; Minami, Tomohiro; Hagiwara, Satoru; Ida, Hiroshi; Ueshima, Kazuomi; Nishida, Naoshi; Murakami, Takamichi; Kudo, Masatoshi
2018-05-01
To assess the clinical feasibility of US-US image overlay fusion with evaluation of the ablative margin in radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). Fifty-three patients with 68 HCCs measuring 0.9-4.0 cm who underwent RFA guided by US-US overlay image fusion were included in this retrospective study. By an overlay of pre-/postoperative US, the tumor image could be projected onto the ablative hyperechoic zone. Therefore, the ablative margin three-dimensionally could be shown during the RFA procedure. US-US image overlay was compared to dynamic CT a few days after RFA for assessment of early treatment response. Accuracy of graded response was calculated, and the performance of US-US image overlay fusion was compared with that of CT using a Kappa agreement test. Technically effective ablation was achieved in a single session, and 59 HCCs (86.8 %) succeeded in obtaining a 5-mm margin on CT. The response with US-US image overlay correctly predicted early CT evaluation with an accuracy of 92.6 % (63/68) (k = 0.67; 95 % CI: 0.39-0.95). US-US image overlay fusion can be proposed as a feasible guidance in RFA with a safety margin and predicts early response of treatment assessment with high accuracy. • US-US image overlay fusion visualizes the ablative margin during RFA procedure. • Visualizing the margin during the procedure can prompt immediate complementary treatment. • US image fusion correlates with the results of early evaluation CT.
Maskery, B; Posey, D L; Coleman, M S; Asis, R; Zhou, W; Painter, J A; Wingate, L T; Roque, M; Cetron, M S
2018-04-01
In 2007, the US Centers for Disease Control and Prevention (CDC) revised its tuberculosis (TB) technical instructions for panel physicians who administer mandatory medical examinations among US-bound immigrants. Many US-bound immigrants come from the Philippines, a high TB prevalence country. To quantify economic and health impacts of smear- vs. culture-based TB screening. Decision tree modeling was used to compare three Filipino screening programs: 1) no screening, 2) smear-based screening, and 3) culture-based screening. The model incorporated pre-departure TB screening results from Filipino panel physicians and CDC databases with post-arrival follow-up outcomes. Costs (2013 $US) were examined from societal, immigrant, US Public Health Department and hospitalization perspectives. With no screening, an annual cohort of 35 722 Filipino immigrants would include an estimated 450 TB patients with 264 hospitalizations, at a societal cost of US$9.90 million. Culture-based vs. smear-based screening would result in fewer imported cases (80.9 vs. 310.5), hospitalizations (19.7 vs. 68.1), and treatment costs (US$1.57 million vs. US$4.28 million). Societal screening costs, including US follow-up, were greater for culture-based screening (US$5.98 million) than for smear-based screening (US$3.38 million). Culture-based screening requirements increased immigrant costs by 61% (US$1.7 million), but reduced costs for the US Public Health Department (22%, US$750 000) and of hospitalization (70%, US$1 020 000). Culture-based screening reduced imported TB and US costs among Filipino immigrants.
Barcelo, Alberto; Arredondo, Armando; Gordillo-Tobar, Amparo; Segovia, Johanna; Qiang, Anthony
2017-12-01
The financial implications of the increase in the prevalence of diabetes in middle-income countries represents one of the main challenges to health system financing and to the society as a whole. The objective of this study was to estimate the economic cost of diabetes in Latin America and the Caribbean (LAC) in 2015. The study used a prevalence-based approach to estimate the direct and indirect costs related to diabetes in 29 LAC countries in 2015. Direct costs included health care expenditures such as medications (insulin and oral hypoglycemic agents), tests, consultations, hospitalizations, emergency visits and treating complications. Two different scenarios (S1 and S2) were used to analyze direct cost. S1 assumed conservative estimates while S2 assumed broader coverage of medication and services. Indirect costs included lost resources due to premature mortality, temporary and permanent disabilities. In 2015 over 41 million adults (20 years of age and more) were estimated to have Diabetes Mellitus in LAC. The total indirect cost attributed to Diabetes was US$ 57.1 billion, of which US$ 27.5 billion was due to premature mortality, US$16.2 billion to permanent disability, and US$ 13.3 billion to temporary disability. The total direct cost was estimated between US$ 45 and US$ 66 billion, of which the highest estimated cost was due to treatment of complications (US$ 1 616 to US$ 26 billion). Other estimates indicated the cost of insulin between US$ 6 and US$ 11 billion; oral medication US$ 4 to US$ 6 billion; consultations between US$ 5 and US$ 6 billion; hospitalization US$ 10 billion; emergency visits US$ 1 billion; test and laboratory exams between US$ 1 and US$ 3 million. The total cost of diabetes in 2015 in LAC was estimated to be between US$ 102 and US$ 123 billion. On average, the annual cost of treating one case of diabetes mellitus (DM) in LAC was estimated between US$ 1088 and US$ 1818. Per capita National Health Expenditures averaged US$ 1061 in LAC. Diabetes represented a major economic burden to the countries of Latin America and the Caribbean in 2015. The estimates presented here are key information for decision-making that can be used in the formulation of policies and programs to achieve greater efficiency and effectiveness in the use of resources for diabetes prevention in the 29 countries of LAC.
Dirrichs, Timm; Quack, Valentin; Gatz, Matthias; Tingart, Markus; Rath, Björn; Betsch, Marcel; Kuhl, Christiane K; Schrading, Simone
2018-03-01
We aimed to investigate the diagnostic accuracy with which shear wave elastography (SWE) can be used to monitor response to treatment of tendinopathies, and to compare it to conventional ultrasound (US)-imaging methods (B-mode US (B-US) and power Doppler US (PD-US)). A prospective Institutional Review Board-approved longitudinal study on 35 patients with 47 symptomatic tendons (17 Achilles-, 15 patellar-, and 15 humeral-epicondylar) who underwent standardized multimodal US and standardized clinical assessment before and after 6 months of treatment (tailored stretching exercise, sport break, and local Polidocanol) was carried out. All US studies were performed by radiologists blinded to the clinical symptoms on both tendon sides to avoid biased interpretations, by B-US, PD-US, and SWE, conducted in the same order, using a high-resolution linear 15 MHz probe (Aixplorer). Orthopedic surgeons who were in turn blinded to US imaging results used established orthopedic scores (Victorian Institute of Sports Assessment questionnaire for Achilles, Victorian Institute of Sports Assessment questionnaire for patellar tendons, and Disability Arm Shoulder Hand scoring system) to rate presence, degree, and possible resolution of symptoms. We analyzed the diagnostic accuracy with which the different US imaging methods were able to detect symptomatic tendons at baseline as well as treatment effects, with orthopedic scores serving as reference standard. B-US, PD-US, and SWE detected symptomatic tendons with a sensitivity of 66% (31 of 47), 72% (34 of 47), and 87.5% (41 of 47), respectively. Positive predictive value was 0.67 for B-US, 0.87 for PD-US, and 1 for SWE. After treatment, clinical scores improved in 68% (32 of 47) of tendons. Treatment effects were observable by B-US, PD-US, and SWE with a sensitivity of 3.1% (1 of 32), 28.1% (9 of 32), and 81.3% (26 of 32), respectively. B-US was false-positive in 68.8% (20 of 32), PD-US in 46.9% (15 of 32), and SWE in 12.5% (4 of 32) (SWE). Clinical scores and B-US, PD-US, and SWE findings correlated poorly (r = 0.24), moderately (r = 0.59), and strongly (r = 0.80). Unlike B-US or PD-US, SWE is able to depict processes associated with tendon healing and may be a useful tool to monitor treatment effects. Copyright © 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.
Barcelo, Alberto; Arredondo, Armando; Gordillo–Tobar, Amparo; Segovia, Johanna; Qiang, Anthony
2017-01-01
BACKGROUND The financial implications of the increase in the prevalence of diabetes in middle–income countries represents one of the main challenges to health system financing and to the society as a whole. The objective of this study was to estimate the economic cost of diabetes in Latin America and the Caribbean (LAC) in 2015. METHODS The study used a prevalence–based approach to estimate the direct and indirect costs related to diabetes in 29 LAC countries in 2015. Direct costs included health care expenditures such as medications (insulin and oral hypoglycemic agents), tests, consultations, hospitalizations, emergency visits and treating complications. Two different scenarios (S1 and S2) were used to analyze direct cost. S1 assumed conservative estimates while S2 assumed broader coverage of medication and services. Indirect costs included lost resources due to premature mortality, temporary and permanent disabilities. RESULTS In 2015 over 41 million adults (20 years of age and more) were estimated to have Diabetes Mellitus in LAC. The total indirect cost attributed to Diabetes was US$ 57.1 billion, of which US$ 27.5 billion was due to premature mortality, US$16.2 billion to permanent disability, and US$ 13.3 billion to temporary disability. The total direct cost was estimated between US$ 45 and US$ 66 billion, of which the highest estimated cost was due to treatment of complications (US$ 1 616 to US$ 26 billion). Other estimates indicated the cost of insulin between US$ 6 and US$ 11 billion; oral medication US$ 4 to US$ 6 billion; consultations between US$ 5 and US$ 6 billion; hospitalization US$ 10 billion; emergency visits US$ 1 billion; test and laboratory exams between US$ 1 and US$ 3 million. The total cost of diabetes in 2015 in LAC was estimated to be between US$ 102 and US$ 123 billion. On average, the annual cost of treating one case of diabetes mellitus (DM) in LAC was estimated between US$ 1088 and US$ 1818. Per capita National Health Expenditures averaged US$ 1061 in LAC. CONCLUSIONS Diabetes represented a major economic burden to the countries of Latin America and the Caribbean in 2015. The estimates presented here are key information for decision–making that can be used in the formulation of policies and programs to achieve greater efficiency and effectiveness in the use of resources for diabetes prevention in the 29 countries of LAC. PMID:29163935
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-21
... 1974; Department of Homeland Security U.S. Citizenship and Immigration Services, U.S. Immigration and... system of records notice titled, ``Department of Homeland Security U.S. Citizenship and Immigration... the Department of Homeland Security U.S. Citizenship and Immigration Services, U.S. Immigration and...
DOT National Transportation Integrated Search
2011-12-21
This report summarizes research conducted along US Highway 64 (US 64) and US Highway 264 (US 264) in Alligator : River National Wildlife Refuge (ARNWR), Dare County, NC regarding the proposed expansion of US 64. The study site : included the areas ad...
Blask, Katarina; Walther, Eva; Frings, Christian
2017-09-01
We investigated in two experiments whether selective attention processes modulate evaluative conditioning (EC). Based on the fact that the typical stimuli in an EC paradigm involve an affect-laden unconditioned stimulus (US) and a neutral conditioned stimulus (CS), we started from the assumption that learning might depend in part upon selective attention to the US. Attention to the US was manipulated by including a variant of the Eriksen flanker task in the EC paradigm. Similarly to the original Flanker paradigm, we implemented a target-distracter logic by introducing the CS as the task-relevant stimulus (i.e. the target) to which the participants had to respond and the US as a task-irrelevant distracter. Experiment 1 showed that CS-US congruence modulated EC if the CS had to be selected against the US. Specifically, EC was more pronounced for congruent CS-US pairs as compared to incongruent CS-US pairs. Experiment 2 disentangled CS-US congruence and CS-US compatibility and suggested that it is indeed CS-US stimulus congruence rather than CS-US response compatibility that modulates EC.
Analysis of Transportation Options for Commercial Spent Fuel in the U.S.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kalinina, Elena; Busch, Ingrid Karin
The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S.more » Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage The U.S. Department of Energy (DOE) is laying the groundwork for implementing interim storage and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF) and high and associated transportation of spent nuclear fuel (SNF) high and associated transportation of spent nuclear fuel (SNF) highand associated transportation of spent nuclear fuel (SNF)...« less
Pallas, Sarah Wood; Courey, Marissa; Hy, Chhaily; Killam, Wm Perry; Warren, Dora; Moore, Brittany
2018-06-04
The Xpert ® MTB/RIF (Xpert) test has been shown to be effective and cost-effective for diagnosing tuberculosis (TB) under conditions with high HIV prevalence and HIV-TB co-infection but less is known about Xpert's cost in low HIV prevalence settings. Cambodia, a country with low HIV prevalence (0.7%), high TB burden, and low multidrug-resistant (MDR) TB burden (1.4% of new TB cases, 11% of retreatment cases) introduced Xpert into its TB diagnostic algorithms for people living with HIV (PLHIV) and people with presumptive MDR TB in 2012. The study objective was to estimate these algorithms' costs pre- and post-Xpert introduction in four provinces of Cambodia. Using a retrospective, ingredients-based microcosting approach, primary cost data on personnel, equipment, maintenance, supplies, and specimen transport were collected at four sites through observation, records review, and key informant consultations. Across the sample facilities, the cost per Xpert test was US$33.88-US$37.11, clinical exam cost US$1.22-US$1.84, chest X-ray cost US$2.02-US$2.14, fluorescent microscopy (FM) smear cost US$1.56-US$1.93, Ziehl-Neelsen (ZN) smear cost US$1.26, liquid culture test cost US$11.63-US$22.83, follow-on work-up for positive culture results and Mycobacterium tuberculosis complex (MTB) identification cost US$11.50-US$14.72, and drug susceptibility testing (DST) cost US$44.26. Specimen transport added US$1.39-US$5.21 per sample. Assuming clinician adherence to the algorithms and perfect test accuracy, the normative cost per patient correctly diagnosed under the post-Xpert algorithms would be US$25-US$29 more per PLHIV and US$34-US$37 more per person with presumptive MDR TB (US$41 more per PLHIV when accounting for variable test sensitivity and specificity). Xpert test unit costs could be reduced through lower cartridge prices, longer usable life of GeneXpert ® (Cepheid, USA) instruments, and increased test volumes; however, epidemiological and test eligibility conditions in Cambodia limit the number of specimens received at laboratories, leading to sub-optimal utilization of current instruments. Improvements to patient referral and specimen transport could increase test volumes and reduce Xpert test unit costs in this setting.
AmeriFlux US-SCd Southern California Climate Gradient - Sonoran Desert
DOE Office of Scientific and Technical Information (OSTI.GOV)
Goulden, Mike
This is the AmeriFlux version of the carbon flux data for the site US-SCd Southern California Climate Gradient - Sonoran Desert. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a low desert site in Southern California's rain shadow; the climate is extremely dry and hot. The site has experience repeated droughts, with negligible rainfall during several years of the record.
Hammig, Bart; Henry, Jean; Davis, Donna
2018-01-31
We examined health insurance coverage among U.S. and Mexican/Central American (M/CA) born labor workers living in the U.S. Using data from the 2010-2015 National Health Interview Survey, we employed logistic regression models to examine health insurance coverage and covariates among U.S. and M/CA born labor workers. Prevalence ratios between U.S. and M/CA born workers were also obtained. U.S. born workers had double the prevalence of insurance coverage. Regarding private insurance coverage, U.S. born workers had a higher prevalence of coverage compared to their M/CA born counterparts. Among foreign born workers with U.S. citizenship, the odds of having insurance coverage was greater than that of noncitizens. Additionally, those who had lived in the U.S. for 10 or more years had higher odds of having health insurance coverage. Disparities in health care coverage exist between U.S. born and foreign born labor workers.
USDA-ARS?s Scientific Manuscript database
The populations of the potato and tomato late blight pathogen, Phytophthora infestans, in the US are well known for emerging repeatedly as novel clonal lineages. These successions of dominant clones have historically been named US1-US24, in order of appearance, since their first characterization usi...
Philip A. Araman
1991-01-01
The exerpts from this seminar are intended to give an overview of U.S. hardwood exports, hardwood exports to Korea, the hardwood resource situation, and the future of U.S. hardwood exports to Korea. It includes 1) some basic information about total U.S. hardwood exports and products, 2) information on hardwood exports to Korea from the U.S., 3) U.S. hardwood resources...
Materials Chemistry of Nanoultrasonic Biomedicine.
Tang, Hailin; Zheng, Yuanyi; Chen, Yu
2017-03-01
As a special cross-disciplinary research frontier, nanoultrasonic biomedicine refers to the design and synthesis of nanomaterials to solve some critical issues of ultrasound (US)-based biomedicine. The concept of nanoultrasonic biomedicine can also overcome the drawbacks of traditional microbubbles and promote the generation of novel US-based contrast agents or synergistic agents for US theranostics. Here, we discuss the recent developments of material chemistry in advancing the nanoultrasonic biomedicine for diverse US-based bio-applications. We initially introduce the design principles of novel nanoplatforms for serving the nanoultrasonic biomedicine, from the viewpoint of synthetic material chemistry. Based on these principles and diverse US-based bio-application backgrounds, the representative proof-of-concept paradigms on this topic are clarified in detail, including nanodroplet vaporization for intelligent/responsive US imaging, multifunctional nano-contrast agents for US-based multi-modality imaging, activatable synergistic agents for US-based therapy, US-triggered on-demand drug releasing, US-enhanced gene transfection, US-based synergistic therapy on combating the cancer and potential toxicity issue of screening various nanosystems suitable for nanoultrasonic biomedicine. It is highly expected that this novel nanoultrasonic biomedicine and corresponding high performance in US imaging and therapy can significantly promote the generation of new sub-discipline of US-based biomedicine by rationally integrating material chemistry and theranostic nanomedicine with clinical US-based biomedicine. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
What Can I Do to Promote a Healthy Pregnancy?
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15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure
Code of Federal Regulations, 2014 CFR
2014-01-01
...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...
15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure
Code of Federal Regulations, 2010 CFR
2010-01-01
...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...
15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure
Code of Federal Regulations, 2013 CFR
2013-01-01
...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...
15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure
Code of Federal Regulations, 2012 CFR
2012-01-01
...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...
15 CFR Supplement No. 5 to Part 748 - U.S. Import Certificate and Delivery Verification Procedure
Code of Federal Regulations, 2011 CFR
2011-01-01
...) Items for which the U.S. Department of Commerce issues U.S. International Import Certificates and forms to use. The Department of Commerce issues U.S. International Import Certificates for the following..., U.S. importers are sometimes required to provide their foreign suppliers with an U.S. International...
Work with Us | Transportation Research | NREL
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-24
... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel And Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open meeting. SUMMARY: The U.S. Travel and Tourism Advisory...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-09
... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION: Notice of an open meeting. SUMMARY: The U.S. Travel and Tourism Advisory...
Are the U.S. territories lagging behind in diabetes care practices?
Ogilvie, Rachel P; Patel, Shivani A; Narayan, K M Venkat; Mehta, Neil K
2018-05-09
Although U.S. territories fall within the mandate outlined by Healthy People 2020, they remain neglected in diabetes care research. We compared the prevalence and secular trends of four recommended diabetes care practices in the U.S. territories of Guam, Puerto Rico, and the U.S. Virgin Islands to the 50 United States and D.C. ("U.S. States") in 2001-2015. Data were from 390,268 adult participants with self-reported physician diagnosed diabetes in the Behavioral Risk Factor Surveillance System. Diabetes care practices included biannual HbA1c tests, attendance of diabetes education classes, daily self-monitoring of blood glucose, and receipt of annual foot examination. Practices were compared by U.S. territory and between territories and U.S. states. Multivariable models accounted for age, sex, education, and year. Of adults with diagnosed diabetes, 7% to 11% in the U.S. territories engaged in all four recommended diabetes care practices compared with 25% for those, on average, in U.S. states. Relative to the U.S. states, on average, the proportion achieving biannual HbA1c testing was lower in Guam and the U.S. Virgin Islands (45.6% and 44.9% vs. 62.2%), while annual foot examinations were lower in Puerto Rico (45.9% vs 66.1% in the U.S. states). Diabetes education and daily glucose self-monitoring were lower in all three territories. U.S. territories lag behind U.S. states in diabetes care practices. Policies aimed at improving diabetes care practices are needed in the U.S. territories to achieve Healthy People 2020 goals and attain parity with U.S. states. Copyright © 2018 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.
Coburger, Jan; Scheuerle, Angelika; Kapapa, Thomas; Engelke, Jens; Thal, Dietmar Rudolf; Wirtz, Christian R; König, Ralph
2015-07-01
Linear array intraoperative ultrasound (lioUS) is an emerging technology for intracranial use. We evaluated sensitivity and specificity of lioUS to detect residual tumor in patients harboring a glioblastoma. After near total resection in 20 patients, residual tumor detection using lioUS, conventional intraoperative ultrasound (cioUS), and gadopentetic-diethylenetriamine penta-acetic acid (Gd-DTPA)-enhanced intraoperative MRI (iMRI) were compared. Sensitivity and specificity were calculated based on 68 navigated biopsies. Receiver operator characteristic (ROC) curves and correlation with histopathological findings of each imaging modality were calculated. Additionally, results were evaluated in the subgroup of recurrent disease (23 biopsies in 8 patients). Sensitivity of lioUS (76 %) was significantly higher compared with iMRI (55 %) and cioUS (24 %). Specificity of lioUS (58 %) was significantly lower than in cioUS (96 %), while there was no significant difference to iMRI (74 %). All imaging modalities correlated significantly with histopathological findings. In the subgroup of recurrent disease, sensitivity and specificity decreased in all modalities. However, cioUS showed significant lower values than iMRI and lioUS. In ROC curves, lioUS showed a higher area und the curve (AUC) in comparison with iMRI and cioUS. We found similar results in the subgroup of recurrent disease. Tumor detection using a lioUS is significantly superior to cioUS. Overall test performance in lioUS is comparable with results of iMRI. While, the latter has a higher specificity and a significantly lower sensitivity in comparison with lioUS.
Ardaens, Y; Robert, Y; Lemaitre, L; Fossati, P; Dewailly, D
1991-06-01
We evaluated the superiority of vaginal ultrasonography (US) on the abdominal US for the diagnosis of polycystic ovarian disease (PCOD). The US pattern of ovaries was prospectively investigated by abdominal US and, whenever possible, by vaginal US. Primary care, institutional. One hundred forty-four women in whom PCOD was suspected on endocrine grounds and 62 other patients presenting with primary hyperprolactinemia (n = 23) or hypothalamic anovulation (n = 39). Vaginal US allowed a better analysis of the ovarian stroma. The external ovarian features of PCOD were observed by both routes in less than one third of the 144 patients with PCOD. The internal ovarian features of PCOD were much more frequently observed by vaginal US than by abdominal US (polycystic pattern: 66.7% versus 38.1%, P less than 0.05; increased ovarian stroma: 57.1% versus 4.8%, P less than 0.001). In the 62 patients without PCOD, US features of PCOD were observed in less than 10% of them, except for the uterine width/ovarian length ratio less than 1 and the polycystic pattern (abdominal US: 17% and 34%; vaginal US: 11% and 50%, respectively). An increased ovarian stroma seems to be the most sensitive and specific US sign of PCOD, providing that it can be investigated by vaginal US.
Characterizing tuberculosis genotype clusters along the United States-Mexico border.
Baker, B J; Moonan, P K
2014-03-01
We examined the growth of tuberculosis (TB) genotype clusters during 2005-2010 in the United States, categorized by country of origin and ethnicity of the index case and geographic proximity to the US-Mexico border at the time of TB diagnosis. Nationwide, 38.9% of cases subsequent to Mexico-born index cases were US-born. Among clusters following US-born Hispanic and US-born non-Hispanic index cases, respectively 29.2% and 5.3% of subsequent cluster members were Mexico-born. In border areas, the majority of subsequent cases were Mexico-born following US-born Hispanic (56.4%) and US-born non-Hispanic (55.6%) index cases. These findings suggest that TB transmission commonly occurs between US-born and Mexico-born persons. Along the US-Mexico border, prioritizing TB genotype clusters following US-born index cases for investigation may prevent subsequent cases among both US-born and Mexico-born persons.
Exploring the Association of Homicides in Northern Mexico and Healthcare Access for US Residents.
Geissler, Kimberley H; Becker, Charles; Stearns, Sally C; Thirumurthy, Harsha; Holmes, George M
2015-08-01
Many legal residents in the United States (US)-Mexico border region cross from the US into Mexico for medical treatment and pharmaceuticals. We analyzed whether recent increases in homicides in Mexico are associated with reduced healthcare access for US border residents. We used data on healthcare access, legal entries to the US from Mexico, and Mexican homicide rates (2002-2010). Poisson regression models estimated associations between homicide rates and total legal US entries. Multivariate difference-in-difference linear probability models evaluated associations between Mexican homicide rates and self-reported measures of healthcare access for US residents. Increased homicide rates were associated with decreased legal entries to the US from Mexico. Contrary to expectations, homicides did not have significant associations with healthcare access measures for legal residents in US border counties. Despite a decrease in border crossings, increased violence in Mexico did not appear to negatively affect healthcare access for US border residents.
Adaptation and application of multivariate AMBI (M-AMBI) in US coastal waters.
Pelletier, Marguerite C; Gillett, David J; Hamilton, Anna; Grayson, Treda; Hansen, Virginia; Leppo, Erik W; Weisberg, Stephan B; Borja, Angel
2018-06-01
The multivariate AMBI (M-AMBI) is an extension of the AZTI Marine Biotic Index (AMBI) that has been used extensively in Europe, but not in the United States. In a previous study, we adapted AMBI for use in US coastal waters (US AMBI), but saw biases in salinity and score distribution when compared to locally calibrated indices. In this study we modified M-AMBI for US waters and compared its performance to that of US AMBI. Index performance was evaluated in three ways: 1) concordance with local indices presently being used as management tools in three geographic regions of US coastal waters, 2) classification accuracy for sites defined a priori as good or bad and 3) insensitivity to natural environmental gradients. US M-AMBI was highly correlated with all three local indices and removed the compression in response seen in moderately disturbed sites with US AMBI. US M-AMBI and US AMBI did a similar job correctly classifying sites as good or bad in local validation datasets (83 to 100% accuracy vs. 84 to 95%, respectively). US M-AMBI also removed the salinity bias of US AMBI so that lower salinity sites were not more likely to be incorrectly classified as impaired. The US M-AMBI appears to be an acceptable index for comparing condition across broad-scales such as estuarine and coastal waters surveyed by the US EPA's National Coastal Condition Assessment, and may be applicable to areas of the US coast that do not have a locally derived benthic index.
McDonald, Jill A; Mojarro Davila, Octavio; Sutton, Paul D; Ventura, Stephanie J
2015-01-01
Cesarean birth (CB) is more prevalent in the US-Mexico border region than among all US Hispanics. Comparable data from US and Mexican birth certificates can be used to compare prevalence and identify risk factors on either side of the border. Using 2009 US and Mexican birth certificates, we compared the characteristics of US Hispanic and Mexican CBs in six geographic subgroups: US and Mexican border counties/municipios, US and Mexican non-border counties/municipios and the US and Mexico overall. We also explored cesarean prevalence over time. During 2000-2009, CB rates increased from 22.1 to 31.6 % among US Hispanics and from 25.9 to 37.9 % among Hispanics in the US border region. 2009 rates were 44.5 % in Mexico and 43.1 % in the Mexican border region. In both countries, CB rates were similar for primiparas and multiparas. Higher education, being married and parity >4 were associated with CB in Mexico; being married was associated in the US. Hispanic rates were higher in the US border than non-border region for all age groups. Along the border, cesarean rates for Hispanics were highest in Texas (43.5 %) and neighboring Tamaulipas (49.8 %). Higher cesarean prevalence in Mexico than in US Hispanics, while unexplained, is consistent with high prevalence in some Latin American countries. Higher cesarean prevalence among Hispanics in the US border region than among Hispanics nationwide cannot be explained by maternal age or parity. Medical indications are also unlikely to explain such high rates, which are undesirable for mothers and infants.
Neuschler, Erin I; Butler, Reni; Young, Catherine A; Barke, Lora D; Bertrand, Margaret L; Böhm-Vélez, Marcela; Destounis, Stamatia; Donlan, Pamela; Grobmyer, Stephen R; Katzen, Janine; Kist, Kenneth A; Lavin, Philip T; Makariou, Erini V; Parris, Tchaiko M; Schilling, Kathy J; Tucker, F Lee; Dogan, Basak E
2018-05-01
Purpose To compare the diagnostic utility of an investigational optoacoustic imaging device that fuses laser optical imaging (OA) with grayscale ultrasonography (US) to grayscale US alone in differentiating benign and malignant breast masses. Materials and Methods This prospective, 16-site study of 2105 women (study period: 12/21/2012 to 9/9/2015) compared Breast Imaging Reporting and Data System (BI-RADS) categories assigned by seven blinded independent readers to benign and malignant breast masses using OA/US versus US alone. BI-RADS 3, 4, or 5 masses assessed at diagnostic US with biopsy-proven histologic findings and BI-RADS 3 masses stable at 12 months were eligible. Independent readers reviewed US images obtained with the OA/US device, assigned a probability of malignancy (POM) and BI-RADS category, and locked results. The same independent readers then reviewed OA/US images, scored OA features, and assigned OA/US POM and a BI-RADS category. Specificity and sensitivity were calculated for US and OA/US. Benign and malignant mass upgrade and downgrade rates, positive and negative predictive values, and positive and negative likelihood ratios were compared. Results Of 2105 consented subjects with 2191 masses, 100 subjects (103 masses) were analyzed separately as a training population and excluded. An additional 202 subjects (210 masses) were excluded due to technical failures or incomplete imaging, 72 subjects (78 masses) due to protocol deviations, and 41 subjects (43 masses) due to high-risk histologic results. Of 1690 subjects with 1757 masses (1079 [61.4%] benign and 678 [38.6%] malignant masses), OA/US downgraded 40.8% (3078/7535) of benign mass reads, with a specificity of 43.0% (3242/7538, 99% confidence interval [CI]: 40.4%, 45.7%) for OA/US versus 28.1% (2120/7543, 99% CI: 25.8%, 30.5%) for the internal US of the OA/US device. OA/US exceeded US in specificity by 14.9% (P < .0001; 99% CI: 12.9, 16.9%). Sensitivity for biopsied malignant masses was 96.0% (4553/4745, 99% CI: 94.5%, 97.0%) for OA/US and 98.6% (4680/4746, 99% CI: 97.8%, 99.1%) for US (P < .0001). The negative likelihood ratio of 0.094 for OA/US indicates a negative examination can reduce a maximum US-assigned pretest probability of 17.8% (low BI-RADS 4B) to a posttest probability of 2% (BI-RADS 3). Conclusion OA/US increases the specificity of breast mass assessment compared with the device internal grayscale US alone. Online supplemental material is available for this article. © RSNA, 2017.
... give us great pleasure. Taste helps us enjoy food and beverages. Smell lets us enjoy the scents and fragrances like roses or coffee. Taste and smell also protect us, letting us know when food has gone bad or when there is a ...
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Code of Federal Regulations, 2014 CFR
2014-04-01
... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. 127.4 Section 127.4 Foreign Relations DEPARTMENT.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and...
Code of Federal Regulations, 2012 CFR
2012-04-01
... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. 127.4 Section 127.4 Foreign Relations DEPARTMENT.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and...
Code of Federal Regulations, 2013 CFR
2013-04-01
... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. 127.4 Section 127.4 Foreign Relations DEPARTMENT.... Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. (a) U.S. Immigration and...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-15
... BE-577: Quarterly Survey of U.S. Direct Investment Abroad-- Direct Transactions of U.S. Reporter With... that it is conducting the mandatory surveys titled BE-577, Quarterly Survey of U.S. Direct Investment Abroad--Direct Transactions of U.S. Reporter with Foreign Affiliate. This survey is authorized by the...
7 CFR 51.685 - U.S. Combination.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Combination. 51.685 Section 51.685 Agriculture....685 U.S. Combination. “U.S. Combination” consists of a combination of U.S. No. 1 and U.S. No. 2 oranges: Provided, That the number of U.S. No. 2 fruits specified in § 51.689, Tables I and II, are not...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-21
... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... agenda for an open meeting of the U.S. Travel and Tourism Advisory Board (Board). The agenda may change...
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2011-08-29
... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... agenda for an open meeting of the U.S. Travel and Tourism Advisory Board (Board). The agenda may change...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-18
... DEPARTMENT OF COMMERCE International Trade Administration U.S. Travel and Tourism Advisory Board: Meeting of the U.S. Travel and Tourism Advisory Board AGENCY: International Trade Administration, U.S... agenda for an open meeting of the U.S. Travel and Tourism Advisory Board (Board). The agenda may change...
17 CFR 151.2 - Core Referenced Futures Contracts.
Code of Federal Regulations, 2012 CFR
2012-04-01
...); (vi) Chicago Board of Trade Wheat (W); (vii) ICE Futures U.S. Cotton No. 2 (CT); (viii) Kansas City... Rice (RR); (vi) ICE Futures U.S. Cocoa (CC); (vii) ICE Futures U.S. Coffee C (KC); (viii) ICE Futures U.S. FCOJ-A(OJ); (ix) ICE Futures U.S. Sugar No. 11 (SB); and (x) ICE Futures U.S. Sugar No. 16 (SF...
17 CFR 151.2 - Core Referenced Futures Contracts.
Code of Federal Regulations, 2014 CFR
2014-04-01
...); (vi) Chicago Board of Trade Wheat (W); (vii) ICE Futures U.S. Cotton No. 2 (CT); (viii) Kansas City... Rice (RR); (vi) ICE Futures U.S. Cocoa (CC); (vii) ICE Futures U.S. Coffee C (KC); (viii) ICE Futures U.S. FCOJ-A(OJ); (ix) ICE Futures U.S. Sugar No. 11 (SB); and (x) ICE Futures U.S. Sugar No. 16 (SF...
17 CFR 151.2 - Core Referenced Futures Contracts.
Code of Federal Regulations, 2013 CFR
2013-04-01
...); (vi) Chicago Board of Trade Wheat (W); (vii) ICE Futures U.S. Cotton No. 2 (CT); (viii) Kansas City... Rice (RR); (vi) ICE Futures U.S. Cocoa (CC); (vii) ICE Futures U.S. Coffee C (KC); (viii) ICE Futures U.S. FCOJ-A(OJ); (ix) ICE Futures U.S. Sugar No. 11 (SB); and (x) ICE Futures U.S. Sugar No. 16 (SF...
AmeriFlux US-SCf Southern California Climate Gradient - Oak/Pine Forest
DOE Office of Scientific and Technical Information (OSTI.GOV)
Goulden, Mike
This is the AmeriFlux version of the carbon flux data for the site US-SCf Southern California Climate Gradient - Oak/Pine Forest. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a mixed oak/pine forest. The site experiences episodic severe drought and mortality, and has also experienced occasional logging and wildfire. Drought and mortality was especially severe in the early 2000s.
International perceptions of US nuclear policy.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stanley, Elizabeth A.
The report presents a summary of international perceptions and beliefs about US nuclear policy, focusing on four countries--China, Iran, Pakistan and Germany--chosen because they span the spectrum of states with which the United States has relationships. A paradox is pointed out: that although the goal of US nuclear policy is to make the United States and its allies safer through a policy of deterrence, international perceptions of US nuclear policy may actually be making the US less safe by eroding its soft power and global leadership position. Broadly held perceptions include a pattern of US hypocrisy and double standards--one setmore » for the US and its allies, and another set for all others. Importantly, the US nuclear posture is not seen in a vacuum, but as one piece of the United States behavior on the world stage. Because of this, the potential direct side effects of any negative international perceptions of US nuclear policy can be somewhat mitigated, dependent on other US policies and actions. The more indirect and long term relation of US nuclear policy to US international reputation and soft power, however, matters immensely to successful multilateral and proactive engagement on other pressing global issues.« less
This dataset consists of site boundaries from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different times and were combined into one region-wide layer. Thus far the sources include:1. California Gulch (Irrigated Meadows) - ESAT Contractor.2. Manning Canyon - U.S. EPA Region 8; ESAT Contractor.3. Rapid City Small Arms Range - U.S. EPA Region 8; ESAT Contractor.4. Animas River/Cement Creek - U.S. EPA Region 8; ESAT Contractor.5. Monticello Mill Tailings (USDOE) - USDOE; ESAT Contractor.6. Pinon Canyon - USDOD.7. Rock Flats Industrial Park - U.S. EPA Region 8.8. Bountiful/Woods Cross - U.S. EPA Region 8.9. Lincoln Park - U.S. EPA Region 8.10. Marshall Landfill - U.S. EPA Region 8.11. U.S. Magnesium - Pacific Western Technologies Inc.
Construction of Silica-Based Micro/Nanoplatforms for Ultrasound Theranostic Biomedicine.
Zhou, Yang; Han, Xiaoxia; Jing, Xiangxiang; Chen, Yu
2017-09-01
Ultrasound (US)-based biomedicine has been extensively explored for its applications in both diagnostic imaging and disease therapy. The fast development of theranostic nanomedicine significantly promotes the development of US-based biomedicine. This progress report summarizes and discusses the recent developments of rational design and fabrication of silica-based micro/nanoparticles for versatile US-based biomedical applications. The synthetic strategies and surface-engineering approaches of silica-based micro/nanoparticles are initially discussed, followed by detailed introduction on their US-based theranostic applications. They have been extensively explored in contrast-enhanced US imaging, US-based multi-modality imaging, synergistic high-intensity focused US (HIFU) ablation, sonosensitizer-enhanced sonodynamic therapy (SDT), as well as US-triggered chemotherapy. Their biological effects and biosafety have been briefly discussed to guarantee further clinical translation. Based on the high biocompatibility, versatile composition/structure and high performance in US-based theranostic biomedicine, these silica-based theranostic agents are expected to pave a new way for achieving efficient US-based theranostics of disease by taking the specific advantages of material science, nanotechnology and US-based biomedicine. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Relevance of Global Health Security to the US Export Economy.
Cassell, Cynthia H; Bambery, Zoe; Roy, Kakoli; Meltzer, Martin I; Ahmed, Zara; Payne, Rebecca L; Bunnell, Rebecca E
To reduce the health security risk and impact of outbreaks around the world, the US Centers for Disease Control and Prevention and its partners are building capabilities to prevent, detect, and contain outbreaks in 49 global health security priority countries. We examine the extent of economic vulnerability to the US export economy posed by trade disruptions in these 49 countries. Using 2015 US Department of Commerce data, we assessed the value of US exports and the number of US jobs supported by those exports. US exports to the 49 countries exceeded $308 billion and supported more than 1.6 million jobs across all US states in agriculture, manufacturing, mining, oil and gas, services, and other sectors. These exports represented 13.7% of all US export revenue worldwide and 14.3% of all US jobs supported by all US exports. The economic linkages between the United States and these global health security priority countries illustrate the importance of ensuring that countries have the public health capacities needed to control outbreaks at their source before they become pandemics.
Relevance of Global Health Security to the US Export Economy
Cassell, Cynthia H.; Bambery, Zoe; Roy, Kakoli; Meltzer, Martin I.; Ahmed, Zara; Payne, Rebecca L.
2017-01-01
To reduce the health security risk and impact of outbreaks around the world, the US Centers for Disease Control and Prevention and its partners are building capabilities to prevent, detect, and contain outbreaks in 49 global health security priority countries. We examine the extent of economic vulnerability to the US export economy posed by trade disruptions in these 49 countries. Using 2015 US Department of Commerce data, we assessed the value of US exports and the number of US jobs supported by those exports. US exports to the 49 countries exceeded $308 billion and supported more than 1.6 million jobs across all US states in agriculture, manufacturing, mining, oil and gas, services, and other sectors. These exports represented 13.7% of all US export revenue worldwide and 14.3% of all US jobs supported by all US exports. The economic linkages between the United States and these global health security priority countries illustrate the importance of ensuring that countries have the public health capacities needed to control outbreaks at their source before they become pandemics. PMID:29199867
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-30
... Environmental Impact Statement for Improvements to the U.S. 17 and Market Street (U.S. 17 Business) Corridor in... and Market Street (U.S. 17 Business) corridor in northern New Hanover and southern Pender Counties... are being evaluated as part of the U.S. 17 Corridor Study. The purpose of the U.S. 17 Corridor Study...
7 CFR 51.624 - U.S. Combination.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 2 2010-01-01 2010-01-01 false U.S. Combination. 51.624 Section 51.624 Agriculture... § 51.624 U.S. Combination. “U.S. Combination” consists of a combination of U.S. No. 1 and U.S. No. 2 grapefruit: Provided, That the number of U.S. No. 2 fruits specified in § 51.628, Tables I and II, are not...
Bottom-up or top-down: unit cost estimation of tuberculosis diagnostic tests in India.
Rupert, S; Vassall, A; Raizada, N; Khaparde, S D; Boehme, C; Salhotra, V S; Sachdeva, K S; Nair, S A; Hoog, A H Van't
2017-04-01
Of 18 sites that participated in an implementation study of the Xpert® MTB/RIF assay in India, we selected five microscopy centres and two reference laboratories. To obtain unit costs of diagnostic tests for tuberculosis (TB) and drug-resistant TB. Laboratories were purposely selected to capture regional variations and different laboratory types. Both bottom-up and the top-down methods were used to estimate unit costs. At the microscopy centres, mean bottom-up unit costs were respectively US$0.83 (range US$0.60-US$1.10) and US$12.29 (US$11.61-US$12.89) for sputum smear microscopy and Xpert. At the reference laboratories, mean unit costs were US$1.69 for the decontamination procedure, US$9.83 for a solid culture, US$11.06 for a liquid culture, US$29.88 for a drug susceptibility test, and US$18.18 for a line-probe assay. Top-down mean unit cost estimates were higher for all tests, and for sputum smear microscopy and Xpert these increased to respectively US$1.51 and US$13.58. The difference between bottom-up and top-down estimates was greatest for tests performed at the reference laboratories. These unit costs for TB diagnostics can be used to estimate resource requirements and cost-effectiveness in India, taking into account geographical location, laboratory type and capacity utilisation.
U.S. trade with Puerto Rico and U.S. possessions, 1996
DOT National Transportation Integrated Search
1997-03-01
The official U.S. import and export statistics reflect both government and nongovernment shipments of merchandise between foreign countries and the U.S. Customs Territory (the 50 States, District of Columbia, and Puerto Rico), U.S. Foreign Trade Zone...
77 FR 73023 - U.S. Environmental Solutions Toolkit
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-07
... foreign end-users of environmental technologies that will outline U.S. approaches to a series of environmental problems and highlight participating U.S. vendors of relevant U.S. technologies. The Toolkit will... DEPARTMENT OF COMMERCE International Trade Administration U.S. Environmental Solutions Toolkit...
Cost of treatment for multidrug-resistant tuberculosis in South Korea.
Kang, Young Ae; Choi, Yong-Jun; Cho, Young-Jae; Lee, Sang Min; Yoo, Chul-Gyu; Kim, Young Whan; Han, Sung Koo; Shim, Young-Soo; Yim, Jae-Joon
2006-11-01
Costs associated with multidrug-resistant tuberculosis (MDR-TB) are higher than those associated with drug-susceptible TB because of the higher prices of second-line anti-TB drugs, the prolonged duration of treatment, greater productivity loss and higher mortality. The aim of this study was to estimate the cost of treatment for MDR-TB according to the treatment strategy and prognosis in South Korea. We estimated the direct (medical and non-medical) and indirect cost for the treatment of MDR-TB according to the treatment strategies and prognosis: in medically treated, surgically treated and deceased patients groups. The same analyses were undertaken for drug-susceptible TB for comparison. The patients with MDR-TB or drug-susceptible TB were randomly selected from the TB cohort of Seoul National University Hospital, Seoul, South Korea. Direct costs per person were US$4000 (US$2527-4841) in the medically treated group, US$17,457 (US$10,133-26,418) in the surgically treated group and US$33,362 (US$25 386-40 338) in the deceased group. Total costs per person were US$15,856 (US$10,752-38,421), US$47,159 (US$20,587-77,622) and US$478,357 (US$257,377-777,778), respectively. For the patients with drug-susceptible TB, the total cost ranged from US$1680 to US$7637 (median US$2166). The cost for the treatment of MDR-TB is seven to 22 times that of managing the drug-susceptible TB in South Korea. Considering the high cost, transmissibility and considerable fatality of MDR-TB, there is a need to provide specific separate funding for multidrug-resistant tuberculosis.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yang, Yang; Wang, Hailong; Smith, Steven J.
Due to US air pollution regulations, aerosol and precursor emissions have decreased during recent decades, while changes in emissions in other regions of the world also influence US aerosol trends through long-range transport. We examine here the relative roles of these domestic and foreign emission changes on aerosol concentrations and direct radiative forcing (DRF) at the top of the atmosphere over the continental US. Long-term (1980-2014) trends and aerosol source apportionment are quantified in this study using a global aerosol-climate model equipped with an explicit aerosol source tagging technique. Due to US emission control policies, the annual mean near-surface concentrationmore » of particles, consisting of sulfate, black carbon, and primary organic aerosol, decreases by about –1.1 (±0.1) / –1.4 (±0.1) μg m -3 in western US and –3.3 (±0.2) / –2.9 (±0.2) μg m -3 in eastern US during 2010–2014, as compared to those in 1980–1984. Meanwhile, decreases in US emissions lead to a warming of +0.48 (±0.03) / –0.46 (±0.03) W m -2 in western US and +1.41 (±0.07) /+1.32 (±0.09) W m -2 in eastern US through changes in aerosol DRF. Increases in emissions from East Asia generally have a modest impact on US air quality, but mitigated the warming effect induced by reductions in US emissions by 25% in western US and 7% in eastern US. Thus, as US domestic aerosol and precursor emissions continue to decrease, foreign emissions may become increasingly important to radiative forcing over the US.« less
Yang, Yang; Wang, Hailong; Smith, Steven J.; ...
2018-05-23
Due to US air pollution regulations, aerosol and precursor emissions have decreased during recent decades, while changes in emissions in other regions of the world also influence US aerosol trends through long-range transport. We examine here the relative roles of these domestic and foreign emission changes on aerosol concentrations and direct radiative forcing (DRF) at the top of the atmosphere over the continental US. Long-term (1980-2014) trends and aerosol source apportionment are quantified in this study using a global aerosol-climate model equipped with an explicit aerosol source tagging technique. Due to US emission control policies, the annual mean near-surface concentrationmore » of particles, consisting of sulfate, black carbon, and primary organic aerosol, decreases by about –1.1 (±0.1) / –1.4 (±0.1) μg m -3 in western US and –3.3 (±0.2) / –2.9 (±0.2) μg m -3 in eastern US during 2010–2014, as compared to those in 1980–1984. Meanwhile, decreases in US emissions lead to a warming of +0.48 (±0.03) / –0.46 (±0.03) W m -2 in western US and +1.41 (±0.07) /+1.32 (±0.09) W m -2 in eastern US through changes in aerosol DRF. Increases in emissions from East Asia generally have a modest impact on US air quality, but mitigated the warming effect induced by reductions in US emissions by 25% in western US and 7% in eastern US. Thus, as US domestic aerosol and precursor emissions continue to decrease, foreign emissions may become increasingly important to radiative forcing over the US.« less
Patients' with type 2 diabetes willingness to pay for insulin therapy and clinical outcomes
Feher, Michael D; Brazier, John; Schaper, Nicolaas; Vega-Hernandez, Gabriela; Bøgelund, Mette
2016-01-01
Objectives This study assessed patient preferences, using willingness to pay as a method to measure different treatment characteristics or attributes associated with injectable insulin therapy in patients with type 2 diabetes. Research design and methods Adults with type 2 diabetes in 12 countries, diagnosed >6 months prior and receiving insulin for >3 months, were recruited through a representative online panel. Data were collected via online questionnaire and analyzed using a standard choice model for discrete choice experiment. Results A total of 3758 patients from North America (n=646), South America (n=1537), and Europe (n=1575) completed the study. Mean glycated hemoglobin (HbA1c) levels in North America, South America, and Europe were 63 mmol/mol (7.9%), 75 mmol/mol (9.0%), and 64 mmol/mol (8.0%), respectively. In the three regions, monthly willingness to pay was US$116, US$74, and US$92, respectively, for a 1%-point decrease in HbA1c; US$99, US$80, and US$104 for one less major hypoglycemic event per year; and US$64, US$37 and US$60 for a 3 kg weight decrease. To avoid preinjection preparation of insulin, the respective values were US$47, US$18, and US$37, and US$25, US$25, and US$24 for one less injection per day. Among respondents on basal-only insulin who had previously tried a more intensive regimen, reasons for switching back included difficulty in handling multiple injections and risk of hypoglycemic events. Conclusions Reducing HbA1c, frequency of major hypoglycemic events and weight decrease were the highest valued outcomes in each region. The administrative burden of injections was also considered important. PMID:27158518
SYMPTOMS OF ANXIETY ON BOTH SIDES OF THE US-MEXICO BORDER: THE ROLE OF IMMIGRATION
Borges, Guilherme; Zamora, Beatriz; García, José; Orozco, Ricardo; Cherpitel, Cheryl J.; Zemore, Sarah E.; Breslau, Joshua
2014-01-01
Home to about 15 million people, the US-Mexico border area has suffered stresses from increased border security efforts and a costly drug war in Mexico. Whether immigration patterns add to increasing levels of anxiety for the Mexican population and the Mexican-origin individuals living in the US-Mexico border and near the border is unknown. We used the US-Mexico Study on Alcohol and Related Conditions (UMSARC), a cross-sectional survey (2011–2013) of individuals living in border and non-border cities of the US (n=2,336) and Mexico (n=2,460). In Mexico respondents were asked if they ever migrated to the US or have a family member living in the US (328) or not (2,124), while in the US respondents were asked if they were born in Mexico (697), born in the US with no US-born parents (second generation, 702) or born in the US with at least one US-born parent (third generation, 932). The prevalence and risk factors for symptoms of anxiety using the Beck Anxiety Inventory (>=10) were obtained. Mexicans with no migrant experience had a prevalence of anxiety and adjusted prevalence ratio (PR) within the last month of 6.7% (PR=reference), followed by Mexicans with migration experience of 13.1% (PR=1.8), Mexican-born respondents living in the US of 17.3% (PR=2.6), US born Mexican-Americans of 2nd generation of 18.6% (PR=3.3) and finally US born 3rd+ generation of 25.9% (PR=3.8). Results help to identify regions and migration patterns at high risk for anxiety and may help to unravel causal mechanisms that underlie this risk. PMID:25543519
Could US mayors achieve the entire US Paris climate target?
NASA Astrophysics Data System (ADS)
Gurney, K. R.; Huang, J.; Hutchins, M.; Liang, J.
2017-12-01
After the recent US Federal Administration announcement not to adhere to the Paris Accords, 359 mayors (and counting) in the US pledged to maintain their commitments, reducing emissions within their jurisdictions by 26-28% from their 2005 levels by the year 2025. While important, this leaves a large portion of the US landscape, and a large amount of US emissions, outside of the Paris commitment. With Federal US policy looking unlikely to change, could additional effort by US cities overcome the gap in national policy and achieve the equivalent US national Paris commitment? How many cities would be required and how deep would reductions need to be? Up until now, this question could not be reliably resolved due to lack of data at the urban scale. Here, we answer this question with new data - the Vulcan V3.0 FFCO2 emissions data product - through examination of the total US energy related CO2 emissions from cities. We find that the top 500 urban areas in the US could meet the national US commitment to the Paris Accords with a reduction of roughly 30% below their 2015 levels by the year 2025. This is driven by the share of US emissions emanating from cities, particularly the largest cohort. Indeed, as the number of urban areas taking on CO2 reduction targets grows, the less the reduction burden on any individual city. In this presentation, we provide an analysis of US urban CO2 emissions and US climate policy, accounting for varying definitions of urban areas, emitting sectors and the tradeoff between the number of policy-active cities and the CO2 reduction burden.
Symptoms of anxiety on both sides of the US-Mexico border: the role of immigration.
Borges, Guilherme; Zamora, Beatriz; García, José; Orozco, Ricardo; Cherpitel, Cheryl J; Zemore, Sarah E; Breslau, Joshua
2015-02-01
Home to about 15 million people, the US-Mexico border area has suffered stresses from increased border security efforts and a costly drug war in Mexico. Whether immigration patterns add to increasing levels of anxiety for the Mexican population and the Mexican-origin individuals living in the US-Mexico border and near the border is unknown. We used the US-Mexico Study on Alcohol and Related Conditions (UMSARC), a cross-sectional survey (2011-2013) of individuals living in border and non-border cities of the US (n = 2336) and Mexico (n = 2460). In Mexico respondents were asked if they ever migrated to the US or have a family member living in the US (328) or not (2124), while in the US respondents were asked if they were born in Mexico (697), born in the US with no US-born parents (second generation, 702) or born in the US with at least one US-born parent (third generation, 932). The prevalence and risk factors for symptoms of anxiety using the Beck Anxiety Inventory (>=10) were obtained. Mexicans with no migrant experience had a prevalence of anxiety and adjusted prevalence ratio (PR) within the last month of 6.7% (PR = reference), followed by Mexicans with migration experience of 13.1% (PR = 1.8), Mexican-born respondents living in the US of 17.3% (PR = 2.6), US born Mexican-Americans of 2nd generation of 18.6% (PR = 3.3) and finally US born 3rd + generation of 25.9% (PR = 3.8). Results help to identify regions and migration patterns at high risk for anxiety and may help to unravel causal mechanisms that underlie this risk. Copyright © 2014 Elsevier Ltd. All rights reserved.
AmeriFlux US-SCs Southern California Climate Gradient - Coastal Sage
DOE Office of Scientific and Technical Information (OSTI.GOV)
Goulden, Mike
This is the AmeriFlux version of the carbon flux data for the site US-SCs Southern California Climate Gradient - Coastal Sage. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a coastal sage shrubland. Coastal sage is a small stature, closed canopy vegetation dominated by drought deciduous shrubs. The site has historically burned every 10-20 years, with the wild fire in October 2007. The tower data sets includes this recovery process.
What we need to know when performing and interpreting US elastography
Park, So Hyun; Kim, So Yeon; Suh, Chong Hyun; Lee, Seung Soo; Kim, Kyoung Won; Lee, So Jung; Lee, Moon-Gyu
2016-01-01
According to the increasing need for accurate staging of hepatic fibrosis, the ultrasound (US) elastography techniques have evolved significantly over the past two decades. Currently, US elastography is increasingly used in clinical practice. Previously published studies have demonstrated the excellent diagnostic performance of US elastography for the detection and staging of liver fibrosis. Although US elastography may seem easy to perform and interpret, there are many technical and clinical factors which can affect the results of US elastography. Therefore, clinicians who are involved with US elastography should be aware of these factors. The purpose of this article is to present a brief overview of US techniques with the relevant technology, the clinical indications, diagnostic performance, and technical and biological factors which should be considered in order to avoid misinterpretation of US elastography results. PMID:27729637
Lee, Junkyo; Lee, Min Woo; Choi, Dongil; Cha, Dong Ik; Lee, Sunyoung; Kang, Tae Wook; Yang, Jehoon; Jo, Jaemoon; Bang, Won-Chul; Kim, Jongsik; Shin, Dongkuk
2017-12-21
The purpose of this study was to evaluate the accuracy of an active contour model for estimating the posterior ablative margin in images obtained by the fusion of real-time ultrasonography (US) and 3-dimensional (3D) US or magnetic resonance (MR) images of an experimental tumor model for radiofrequency ablation. Chickpeas (n=12) and bovine rump meat (n=12) were used as an experimental tumor model. Grayscale 3D US and T1-weighted MR images were pre-acquired for use as reference datasets. US and MR/3D US fusion was performed for one group (n=4), and US and 3D US fusion only (n=8) was performed for the other group. Half of the models in each group were completely ablated, while the other half were incompletely ablated. Hyperechoic ablation areas were extracted using an active contour model from real-time US images, and the posterior margin of the ablation zone was estimated from the anterior margin. After the experiments, the ablated pieces of bovine rump meat were cut along the electrode path and the cut planes were photographed. The US images with the estimated posterior margin were compared with the photographs and post-ablation MR images. The extracted contours of the ablation zones from 12 US fusion videos and post-ablation MR images were also matched. In the four models fused under real-time US with MR/3D US, compression from the transducer and the insertion of an electrode resulted in misregistration between the real-time US and MR images, making the estimation of the ablation zones less accurate than was achieved through fusion between real-time US and 3D US. Eight of the 12 post-ablation 3D US images were graded as good when compared with the sectioned specimens, and 10 of the 12 were graded as good in a comparison with nicotinamide adenine dinucleotide staining and histopathologic results. Estimating the posterior ablative margin using an active contour model is a feasible way of predicting the ablation area, and US/3D US fusion was more accurate than US/MR fusion.
New Cyber Chief: Cyberspace Must Become a National Security Priority
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Code of Federal Regulations, 2014 CFR
2014-07-01
... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...
Code of Federal Regulations, 2013 CFR
2013-07-01
... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...
Code of Federal Regulations, 2011 CFR
2011-07-01
... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...
Code of Federal Regulations, 2012 CFR
2012-07-01
... FOR OTHERS § 555.2 Applicability. This regulation applies to the U.S. Army Engineer Waterways Experiment Station (WES), the U.S. Army Construction Engineering Research Laboratory (CERL), the U.S. Army Engineer Topographic Laboratories (ETL), the U.S. Army Coastal Engineering Research Center (CERC), the U.S...
USDA-ARS?s Scientific Manuscript database
The Agricultural Research Service, U.S. Department of Agriculture, hereby releases for propagation the US SEEDLESS PINEAPPLE citrus scion selection, formerly tested as USDA 1-10-60. US SEEDLESS PINEAPPLE resulted from irradiation of Ridge Pineapple seeds by C.J. Hearn in 1970 at the U.S. Horticultu...
Exploring the association of homicides in northern Mexico and healthcare access for US residents
Geissler, Kimberley; Becker, Charles; Stearns, Sally; Thirumurthy, Harsha; Holmes, George M.
2016-01-01
Background Many legal residents in the United States (US)-Mexico border region cross from the US into Mexico for medical treatment and pharmaceuticals. We analyzed whether recent increases in homicides in Mexico are associated with reduced healthcare access for US border residents. Methods We used data on healthcare access, legal entries to the US from Mexico, and Mexican homicide rates (2002–2010). Poisson regression models estimated associations between homicide rates and total legal US entries. Multivariate difference-in-difference linear probability models evaluated associations between Mexican homicide rates and self-reported measures of healthcare access for US residents. Results Increased homicide rates were associated with decreased legal entries to the US from Mexico. Contrary to expectations, homicides did not have significant associations with healthcare access measures for legal residents in US border counties. Conclusions Despite a decrease in border crossings, increased violence in Mexico did not appear to negatively affect access for US border residents. PMID:24917240
US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview
2017-11-01
ARL-TR-8199 ● NOV 2017 US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing...US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview by Roger P...TITLE AND SUBTITLE US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview 5a. CONTRACT NUMBER 5b. GRANT
Health Issues for the Hmong Population in the U.S.: Implications for Health Educators
ERIC Educational Resources Information Center
Pinzon-Perez, Helda
2006-01-01
The Hmong population in the US has grown since 1975. According to the 2000 US census, there are more than 160,000 Hmong living in the US. New waves of Hmong immigrants are re-settling in the US. Over 15,000 Hmong have come to the US from Thailand as refugees since summer 2004. California, Minnesota, and Wisconsin are the States with the highest…
Usher syndrome in the city of Birmingham—prevalence and clinical classification
Hope, C; Bundey, S; Proops, D; Fielder, A
1997-01-01
AIMS—To estimate the prevalence of Usher syndrome in the city of Birmingham, and to establish a database of patients who have been classified into different clinical subtypes essential for future gene mutation analysis. METHODS—Symptomatic cases of Usher syndrome (US) resident in the city of Birmingham in June 1994 were ascertained through multiple sources. Ophthalmic and audiological reassessment together with examination of medical records and patient questionnaires allowed classification of three subtypes, US 1, US 2, and US 3. In addition, family pedigrees were examined and blood was taken from index patients for DNA extraction. RESULTS—In the population aged over 15 years the prevalence was 6.2 per 100 000 population for all US subtypes. The prevalence for US 1 and US 2 was 5.3 per 100 000 population. This is greater than previously reported. In the age group 30-49 years the prevalence approached 1 in 10 000. Clinical classification found 33% US 1, 47% US 2, and 20% US 3. CONCLUSION—This higher prevalence rate and greater frequency of US 2 and US 3 may reflect a more complete ascertainment. PMID:9135408
Brooks, Ingrid A; Sayre, Michael R; Spencer, Caroline; Archer, Frank L
2016-02-01
The Emergency Medical Services (EMS) approach to emergency prehospital care in the United States (US) has global influence. As the 50-year anniversary of modern US EMS approaches, there is value in examining US EMS education development over this period. This report describes US EMS education milestones and identifies themes that provide context to readers outside the US. As US EMS education is described mainly in publications of federal US EMS agencies and associations, a Google search and hand searching of documents identified publications in the public domain. MEDLINE and CINAHL Plus were searched for peer reviewed publications. Documents were reviewed using both a chronological and thematic approach. Seventy-eight documents and 685 articles were screened, the full texts of 175 were reviewed, and 41 were selected for full review. Four historical periods in US EMS education became apparent: EMS education development (1966-1980); EMS education consolidation and review (1981-1989); EMS education reflection and change (1990-1999); and EMS education for the future (2000-2014). Four major themes emerged: legislative authority, physician direction, quality, and development of the profession. Documents produced through broad interprofessional consultations, with support from federal and US EMS authorities, reflect the catalysts for US EMS education development. The current model of US EMS education provides a structure to enhance educational quality into the future. Implementation evaluation of this model would be a valuable addition to the US EMS literature. The themes emerging from this review assist the understanding of the characteristics of US EMS education.
Baek, Jihye; Huh, Jangyoung; Kim, Myungsoo; Hyun An, So; Oh, Yoonjin; Kim, DongYoung; Chung, Kwangzoo; Cho, Sungho; Lee, Rena
2013-02-01
To evaluate the accuracy of measuring volumes using three-dimensional ultrasound (3D US), and to verify the feasibility of the replacement of CT-MR fusion images with CT-3D US in radiotherapy treatment planning. Phantoms, consisting of water, contrast agent, and agarose, were manufactured. The volume was measured using 3D US, CT, and MR devices. A CT-3D US and MR-3D US image fusion software was developed using the Insight Toolkit library in order to acquire three-dimensional fusion images. The quality of the image fusion was evaluated using metric value and fusion images. Volume measurement, using 3D US, shows a 2.8 ± 1.5% error, 4.4 ± 3.0% error for CT, and 3.1 ± 2.0% error for MR. The results imply that volume measurement using the 3D US devices has a similar accuracy level to that of CT and MR. Three-dimensional image fusion of CT-3D US and MR-3D US was successfully performed using phantom images. Moreover, MR-3D US image fusion was performed using human bladder images. 3D US could be used in the volume measurement of human bladders and prostates. CT-3D US image fusion could be used in monitoring the target position in each fraction of external beam radiation therapy. Moreover, the feasibility of replacing the CT-MR image fusion to the CT-3D US in radiotherapy treatment planning was verified.
Royer, Danielle F
2016-10-01
Ultrasound (US) is increasingly taught in medical schools, where it has been shown to be a valuable adjunct to anatomy training. To determine the extent of US training in nonmedical anatomy programs, and evaluate anatomists' perceptions on the role of US in anatomy education, an online survey was distributed to faculty in anatomy Master's and Doctoral programs. Survey results sampled 71% of anatomy graduate degree programs nationally. Of the faculty surveyed, 65% report little to no experience with US. Thirty-six percent of programs surveyed incorporate exposure to US, while only 15% provide hands-on US training. Opportunities for anatomy trainees to teach with US were found in 12% of programs. Likert responses indicated that anatomists hold overwhelmingly positive views on the contributions of US to anatomy education: 91% agreed US reinforces anatomical concepts (average 4.33 ± 0.68), 95% agreed it reinforces clinical correlates (average 4.43 ± 0.65). Anatomists hold moderately positive views on the value of US to the future careers of anatomy graduates: 69% agreed US increases competitiveness on the job market (average 3.91 ± 0.90), 85% agreed US is a useful skill for a medical school teaching career (average 4.24 ± 0.75), and 41% agreed that US should be required for a medical education career (average 3.34 ± 1.09). With continued improvements in technology and the widespread adoption of US into diverse areas of clinical practice, medical education is on the cusp of a paradigm shift with regards to US. Anatomists must decide whether US is an essential skills for the modern anatomist. Anat Sci Educ 9: 453-467. © 2016 American Association of Anatomists. © 2016 American Association of Anatomists.
TOXICITY TESTING, RISK ASSESSMENT, AND OPTIONS FOR DREDGED MATRIAL MANAGEMENT
The U.S. Environmental Protection Agency (U.S. EPA), in conjunction with the U.S. Army Corps of Engineers (U.S. ACE), has lead responsibility for developing guidelines that provide environmental criteria for evaluating proposed discharges of dredged material into U.S. waters. To ...
78 FR 14773 - U.S. Environmental Solutions Toolkit-Landfill Standards
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-07
... and foreign end-users of environmental technologies that will outline U.S. approaches to a series of environmental problems and highlight participating U.S. vendors of relevant U.S. technologies. The Toolkit will... DEPARTMENT OF COMMERCE International Trade Administration U.S. Environmental Solutions Toolkit...
STEM Interns Get Real-World Experience in NHRC's Virtual Reality Lab
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78 FR 58520 - U.S. Environmental Solutions Toolkit
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-24
... notice sets forth a request for input from U.S. businesses capable of exporting their goods or services... and foreign end-users of environmental technologies The Toolkit outline U.S. approaches to a series of environmental problems and highlight participating U.S. vendors of relevant U.S. technologies. The Toolkit will...
USPAS | U.S. Particle Accelerator School
U.S. Particle Accelerator School U.S. Particle Accelerator School U.S. Particle Accelerator School U.S. Particle Accelerator School Education in Beam Physics and Accelerator Technology Home About About University Credits Joint International Accelerator School University-Style Programs Symposium-Style Programs
76 FR 65207 - U.S. Customs and Border Protection
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-20
... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Notice of Cancellation of Customs Broker Licenses AGENCY: U.S. Customs and Border Protection, U.S. Department of Homeland Security.... 1641) and the U.S. Customs and Border Protection regulations (19 CFR 111.51), the following Customs...
75 FR 70215 - Environmental Technologies Trade Advisory Committee (ETTAC), Request for Nominations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-17
... relating to U.S. environmental technologies exports; U.S. Government policies and programs on the export of U.S. environmental products, technologies, and services; the effect of foreign governments' policies... and services companies, U.S. trade associations, and U.S. private sector organizations involved in the...
2016-04-21
Congressional Nominations to U.S. Service Academies: An Overview and Resources for Outreach and Management R. Eric Petersen Specialist in...www.crs.gov RL33213 Congressional Nominations to U.S. Service Academies: An Overview Congressional Research Service Summary Members of Congress are...authorized by law to nominate candidates for appointment to four U.S. service academies. These schools are the U.S. Military Academy, the U.S. Naval
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-30
... Trading of iShares Strategic Beta U.S. Large Cap Fund and iShares Strategic Beta U.S. Small Cap Fund Under... Fund Shares''): iShares Strategic Beta U.S. Large Cap Fund and iShares Strategic Beta U.S. Small Cap...: \\3\\ iShares Strategic Beta U.S. Large Cap Fund and iShares Strategic Beta U.S. Small Cap Fund (each...
Prakash Nepal; Peter J. Ince; Kenneth E. Skog; Sun J. Chang
2012-01-01
This study provides a modeling framework to examine change over time in U.S. forest sector carbon inventory (in U.S. timberland tree biomass and harvested wood products) for alternative projections of U.S. and global timber markets, including wood energy consumption, based on established IPCC/RPA scenarios. Results indicated that the U.S. forest sectorâs projected...
Tankering Fuel: A Cost Saving Initiative
2011-05-01
USAF AFIT/IMO/ENS/11-06 DEPARTMENT OF THE AIR FORCE AIR UNIVERSITY AIR FORCE INSTITUTE OF TECHNOLOGY Wright- Patterson Air Force Base, Ohio...NORTHCOM DFSP Verona DESC New York US NULL NORTHCOM DFSP Watson DESC California US NULL NORTHCOM DFSP WILLIAMS DESC FLOATING US NULL NORTHCOM DFSP...ANG KOKC AF Oklahoma US ANG NORTHCOM Willow Grove ANG KNXX AF Pennsylvania US ANG NORTHCOM Wright Patterson KFFO AF Ohio US AFMC NORTHCOM WV ARNG
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-03
... DEPARTMENT OF STATE [Public Notice 7476] U.S. Advisory Panel to the U.S. Section of the North Pacific Anadromous Fish Commission; Notice of Renewal The Department of State has renewed the Charter of the U.S. Advisory Panel to the U.S. Section of the North Pacific Anadromous Fish Commission (NPAFC) for another two years. The NPAFC was established...
U.S. Crude Oil and Natural Gas Proved Reserves
2016-01-01
U.S. oil and natural gas proved reserves declined in 2015 due to lower prices. U.S. crude oil and lease condensate proved reserves declined 4.7 billion barrels (11.8%) from their year-end 2014 level to 35.2 billion barrels at year-end 2015, according to U.S. Crude Oil and Natural Gas Proved Reserves, Year-end 2015, released today by the U.S. Energy Information Administration. U.S natural gas proved reserves decreased 64.5 trillion cubic feet, a 16.6% decline, reducing the U.S. total to 324.3 Tcf at year-end 2015.
[Unit cost variation in a social security company in Querétaro, México].
Villarreal-Ríos, Enrique; Campos-Esparza, Maribel; Garza-Elizondo, María E; Martínez-González, Lidia; Núñez-Rocha, Georgina M; Romero-Islas, Nestor R
2006-01-01
Comparing unit cost variation between departments and reasons for consultation in outpatient health services provided by a social security company from Querétaro, Mexico. A study of costs (in US dollars) was carried out in outpatient health service units during 2004. Fixed unit costs were estimated per department and adjusted for one year's productivity. Material, physical and consumer resources were included. Weighting was assigned to resources invested in each department. Unit cost was estimated by using the micro cost technique; medicaments, materials used during treatment and reagents were considered to be consumer items. Unit cost resulted from adding fixed unit cost to the variable unit cost corresponding to the reason for consulting. Units costs were then compared between the medical units. Unit cost per month for diabetic treatment varied from 34.8 US dollars, 32,2 US dollars to US 34 US dollars, pap smear screening test costs were 7,2 US dollars, 8,7 US dollars and 7,3 US dollars and dental treatment 27 US dollars, 33 US dollars, 6 and 28,7 US dollars. Unit cost variation was more important in the emergency room and the dental service.
Kang, Ming-Hsi; Roy, Bibhuti B; Finnen, Renée L; Le Sage, Valerie; Johnston, Susan M; Zhang, Hui; Banfield, Bruce W
2013-09-01
The Us2 gene encodes a tegument protein that is conserved in most members of the Alphaherpesvirinae. Previous studies on the pseudorabies virus (PRV) Us2 ortholog indicated that it is prenylated, associates with membranes, and spatially regulates the enzymatic activity of the MAP (mitogen-activated protein) kinase ERK (extracellular signal-related kinase) through direct binding and sequestration of ERK at the cytoplasmic face of the plasma membrane. Here we present an analysis of the herpes simplex virus 2 (HSV-2) Us2 ortholog and demonstrate that, like PRV Us2, HSV-2 Us2 is a virion component and that, unlike PRV Us2, it does not interact with ERK in yeast two-hybrid assays. HSV-2 Us2 lacks prenylation signals and other canonical membrane-targeting motifs yet is tightly associated with detergent-insoluble membranes and localizes predominantly to recycling endosomes. Experiments to identify cellular proteins that facilitate HSV-2 Us2 membrane association were inconclusive; however, these studies led to the identification of HSV-2 Us2 as a ubiquitin-interacting protein, providing new insight into the functions of HSV-2 Us2.
Kim, Dong Wook
2015-08-01
The aim of this study was to compare the diagnostic accuracy of real-time and static ultrasonography (US) for the incidental detection of diffuse thyroid disease (DTD). In 118 consecutive patients, a single radiologist performed real-time US before thyroidectomy. For static US, the same radiologist retrospectively investigated the sonographic findings on a picture-archiving and communication system after 3 months. The diagnostic categories of both real-time and static US diagnoses were determined based on the number of abnormal findings, and the diagnostic indices were calculated by a receiver operating characteristic (ROC) curve analysis using the histopathologic results as the reference standard. Histopathologic results included normal thyroid (n = 77), Hashimoto thyroiditis (n = 11), non-Hashimoto lymphocytic thyroiditis (n = 29), and diffuse hyperplasia (n = 1). Normal thyroid and DTD showed significant differences in echogenicity, echotexture, glandular margin, and vascularity on both real-time and static US. There was a positive correlation between US categories and histopathologic results in both real-time and static US. The highest diagnostic indices were obtained when the cutoff criteria of real-time and static US diagnoses were chosen as indeterminate and suspicious for DTD, respectively. The ROC curve analysis showed that real-time US was superior to static US in diagnostic accuracy. Both real-time and static US may be helpful for the detection of incidental DTD, but real-time US is superior to static US for detecting incidental DTD.
Schlosser, Jeffrey; Gong, Ren Hui; Bruder, Ralf; Schweikard, Achim; Jang, Sungjune; Henrie, John; Kamaya, Aya; Koong, Albert; Chang, Daniel T; Hristov, Dimitre
2016-11-01
To present a system for robotic 4D ultrasound (US) imaging concurrent with radiotherapy beam delivery and estimate the proportion of liver stereotactic ablative body radiotherapy (SABR) cases in which robotic US image guidance can be deployed without interfering with clinically used VMAT beam configurations. The image guidance hardware comprises a 4D US machine, an optical tracking system for measuring US probe pose, and a custom-designed robot for acquiring hands-free US volumes. In software, a simulation environment incorporating the LINAC, couch, planning CT, and robotic US guidance hardware was developed. Placement of the robotic US hardware was guided by a target visibility map rendered on the CT surface by using the planning CT to simulate US propagation. The visibility map was validated in a prostate phantom and evaluated in patients by capturing live US from imaging positions suggested by the visibility map. In 20 liver SABR patients treated with VMAT, the simulation environment was used to virtually place the robotic hardware and US probe. Imaging targets were either planning target volumes (PTVs, range 5.9-679.5 ml) or gross tumor volumes (GTVs, range 0.9-343.4 ml). Presence or absence of mechanical interference with LINAC, couch, and patient body as well as interferences with treated beams was recorded. For PTV targets, robotic US guidance without mechanical interference was possible in 80% of the cases and guidance without beam interference was possible in 60% of the cases. For the smaller GTV targets, these proportions were 95% and 85%, respectively. GTV size (1/20), elongated shape (1/20), and depth (1/20) were the main factors limiting the availability of noninterfering imaging positions. The robotic US imaging system was deployed in two liver SABR patients during CT simulation with successful acquisition of 4D US sequences in different imaging positions. This study indicates that for VMAT liver SABR, robotic US imaging of a relevant internal target may be possible in 85% of the cases while using treatment plans currently deployed in the clinic. With beam replanning to account for the presence of robotic US guidance, intrafractional US may be an option for 95% of the liver SABR cases.
Cooper, David T; Behrens, Claus F
2016-01-01
Objective: In cervical radiotherapy, it is essential that the uterine position is correctly determined prior to treatment delivery. The aim of this study was to evaluate an autoscan ultrasound (A-US) probe, a motorized transducer creating three-dimensional (3D) images by sweeping, by comparing it with a conventional ultrasound (C-US) probe, where manual scanning is required to acquire 3D images. Methods: Nine healthy volunteers were scanned by seven operators, using the Clarity® system (Elekta, Stockholm, Sweden). In total, 72 scans, 36 scans from the C-US and 36 scans from the A-US probes, were acquired. Two observers delineated the uterine structure, using the software-assisted segmentation in the Clarity workstation. The data of uterine volume, uterine centre of mass (COM) and maximum uterine lengths, in three orthogonal directions, were analyzed. Results: In 53% of the C-US scans, the whole uterus was captured, compared with 89% using the A-US. F-test on 36 scans demonstrated statistically significant differences in interobserver COM standard deviation (SD) when comparing the C-US with the A-US probe for the inferior–superior (p < 0.006), left–right (p < 0.012) and anteroposterior directions (p < 0.001). The median of the interobserver COM distance (Euclidean distance for 36 scans) was reduced from 8.5 (C-US) to 6.0 mm (A-US). An F-test on the 36 scans showed strong significant differences (p < 0.001) in the SD of the Euclidean interobserver distance when comparing the C-US with the A-US scans. The average Dice coefficient when comparing the two observers was 0.67 (C-US) and 0.75 (A-US). The predictive interval demonstrated better interobserver delineation concordance using the A-US probe. Conclusion: The A-US probe imaging might be a better choice of image-guided radiotherapy system for correcting for daily uterine positional changes in cervical radiotherapy. Advances in knowledge: Using a novel A-US probe might reduce the uncertainty in interoperator variability during ultrasound scanning. PMID:27452268
Baker, Mariwan; Cooper, David T; Behrens, Claus F
2016-10-01
In cervical radiotherapy, it is essential that the uterine position is correctly determined prior to treatment delivery. The aim of this study was to evaluate an autoscan ultrasound (A-US) probe, a motorized transducer creating three-dimensional (3D) images by sweeping, by comparing it with a conventional ultrasound (C-US) probe, where manual scanning is required to acquire 3D images. Nine healthy volunteers were scanned by seven operators, using the Clarity(®) system (Elekta, Stockholm, Sweden). In total, 72 scans, 36 scans from the C-US and 36 scans from the A-US probes, were acquired. Two observers delineated the uterine structure, using the software-assisted segmentation in the Clarity workstation. The data of uterine volume, uterine centre of mass (COM) and maximum uterine lengths, in three orthogonal directions, were analyzed. In 53% of the C-US scans, the whole uterus was captured, compared with 89% using the A-US. F-test on 36 scans demonstrated statistically significant differences in interobserver COM standard deviation (SD) when comparing the C-US with the A-US probe for the inferior-superior (p < 0.006), left-right (p < 0.012) and anteroposterior directions (p < 0.001). The median of the interobserver COM distance (Euclidean distance for 36 scans) was reduced from 8.5 (C-US) to 6.0 mm (A-US). An F-test on the 36 scans showed strong significant differences (p < 0.001) in the SD of the Euclidean interobserver distance when comparing the C-US with the A-US scans. The average Dice coefficient when comparing the two observers was 0.67 (C-US) and 0.75 (A-US). The predictive interval demonstrated better interobserver delineation concordance using the A-US probe. The A-US probe imaging might be a better choice of image-guided radiotherapy system for correcting for daily uterine positional changes in cervical radiotherapy. Using a novel A-US probe might reduce the uncertainty in interoperator variability during ultrasound scanning.
U.S. healthcare fix: leveraging the lessons from the food supply chain.
Kumar, Sameer; Blair, John T
2013-01-01
U.S. healthcare costs consistently outpace inflation, causing growing problems of affordability. This trend cannot be sustained indefinitely. The purpose of this study is to use supply-chain tools for macro-level examination of the U.S. healthcare as a business system and identify options and best use practices. We compare the important and successful U.S. food industry to the essential but problematic U.S. healthcare industry. Supply chain strategies leading to food business operations success are examined and healthcare applications suggested. We emphasize "total cost of ownership" which includes all costs incurred by all stakeholders of U.S. healthcare, including maintenance and cleanup, not just the initial purchase price. U.S. hospitals and clinics can use supply chain strategies in a total cost of ownership framework to reduce healthcare costs while maintaining patient care quality. Supply chain strategies of resource pooling, mass customization, centralized logistics, specialization, postponement and continuous improvement that have been successfully used in the U.S. food industry should be more widely applied to the U.S. healthcare industry. New and growing areas of telemedicine and medical tourism should be included in the supply chain analysis of U.S. healthcare. Valid statistical analysis of results in all areas of U.S. healthcare is an important part of the process. U.S. healthcare industry problems are systematic operational and supply chain problems rather than problems with workforce or technology. Examination of the U.S. healthcare industry through a supply chain framework should lead to significant operational improvement in both prevention and treatment of acute and chronic ailments. A rational and unemotional reorganization of the U.S. healthcare system operations, using supply chain strategies, should help reduce healthcare costs while maintaining quality and increasing accessibility.
Tranquart, F; Bleuzen, A; Kissel, A
2004-06-01
To assess the value of combined conventional and contrast-material enhanced sonography for the characterization of focal liver lesions. Simultaneous imaging with grey scale and contrast enhanced US was performed in 90 patients following Levovist injection (Schering, Berlin, Germany) using the "Agent Detection Imaging" method (ADI, Siemens-Acuson, Mountain View, USA). US scanning was performed at least 4 minutes after contrast injection with review of both grayscale and contrast enhanced modes. Results for detection and characterization of lesions were compared to the selected gold standard imaging modality (CT or MRI). Final diagnoses included: 20 normal examinations, 41 patients with metastases, 6 patients with hepatocellular carcinoma, 13 patients with hemangioma, 6 patients with other benign lesions, 4 patients with cysts and 6 patients with two types of lesions. Delayed phase contrast enhanced US allowed diagnosis of all lesions except for one metastasis and all hepatocellular carcinomas. While the diagnosis of hepatoma could not be confirmed, the features suggested a malignant etiology. For 7 patients with metastases, more lesions were detected at ADI (4.9 lesions) than at conventional US (1.1 lesion). For 3 patients, CT showed more lesions than ADI US (3.3 versus 1.6 lesions). The accuracy of ADI US for differentiating between benign and malignant lesions was 98.7% compared to 49.6% for conventional US (p<0.001). The total number of lesions detected at ADI US was higher (p<0.01) than at conventional US and not significantly different from that obtained by the gold standard reference methods. Complete characterization was achieved in 92.2% of cases with ADI US compared to 59.2% with conventional US (p<0.001). Contrast-material enhanced US combined with conventional US markedly improves the diagnostic accuracy of US in terms of lesion detection and characterization.
The cost of antiretroviral therapy in Haiti
Koenig, Serena P; Riviere, Cynthia; Leger, Paul; Severe, Patrice; Atwood, Sidney; Fitzgerald, Daniel W; Pape, Jean W; Schackman, Bruce R
2008-01-01
Background We determined direct medical costs, overhead costs, societal costs, and personnel requirements for the provision of antiretroviral therapy (ART) to patients with AIDS in Haiti. Methods We examined data from 218 treatment-naïve adults who were consecutively initiated on ART at the GHESKIO Center in Port-au-Prince, Haiti between December 23, 2003 and May 20, 2004 and calculated costs and personnel requirements for the first year of ART. Results The mean total cost of treatment per patient was $US 982 including $US 846 in direct costs, $US 114 for overhead, and $US 22 for societal costs. The direct cost per patient included generic ART medications $US 355, lab tests $US 130, nutrition $US 117, hospitalizations $US 62, pre-ART evaluation $US 58, labor $US 51, non-ART medications $US 39, outside referrals $US 31, and telephone cards for patient retention $US 3. Higher treatment costs were associated with hospitalization, change in ART regimen, TB treatment, and survival for one year. We estimate that 1.5 doctors and 2.5 nurses are required to treat 1000 patients in the first year after initiating ART. Conclusion Initial ART treatment in Haiti costs approximately $US 1,000 per patient per year. With generic first-line antiretroviral drugs, only 36% of the cost is for medications. Patients who change regimens are significantly more expensive to treat, highlighting the need for less-expensive second-line drugs. There may be sufficient health care personnel to treat all HIV-infected patients in urban areas of Haiti, but not in rural areas. New models of HIV care are needed for rural areas using assistant medical officers and community health workers. PMID:18275615
Joos, Els; Vansteenwegen, Debora; Hermans, Dirk
2012-06-01
Although repetitive thought (e.g., worry) is generally assumed to be a risk factor for psychopathological disorders such as anxiety disorders, the repetitive thought processes occurring after a conditioning event have not yet received much theoretical attention. However, as repetitive thought can be mimicked by (mental) rehearsal, which is well-known to enhance memory performance, it seems worthwhile to explore the role of rehearsal in conditioning. Therefore, the current study investigates the impact of rehearsing an acquired CS-US-contingency on subsequent conditioned fear responding. After acquiring two CS-US-contingencies with either a human scream or a white noise as US, participants were instructed to rehearse one of these CS-US-pairings during an experimental session as well as during the following week. Fear responding to the CS which was previously paired with the scream persisted in the participants who rehearsed the CS-US(scream)-contingency, but decreased in those participants who rehearsed the CS-US(noise)-contingency. The same pattern emerged in the US-expectancy ratings, but the effect failed to reach significance. For the CS which was paired with the noise-US, no rehearsal effect emerged. As acquisition to the noise-US was less pronounced and less robust as compared to the scream-US, claims regarding the rehearsal effect might be hampered for the CS-US(noise)-contingency. Repetitive post-acquisition activation of a CS-US-contingency impacts CR retention. As the USs were not rated as more intense, aversive or startling after rehearsal compared to post-acquisition, US-inflation is discarded as a possible explanation of this effect. Copyright © 2011 Elsevier Ltd. All rights reserved.
Hwang, Eun Gu; Lee, Yunjung
2016-12-01
Simple radiography is the best diagnostic tool for rib fractures caused by chest trauma, but it has some limitations. Thus, other tools are also being used. The aims of this study were to investigate the effectiveness of ultrasonography (US) for identifying rib fractures and to identify influencing factors of its effectiveness. Between October 2003 and August 2007, 201 patients with blunt chest trauma were available to undergo chest radiographic and US examinations for diagnosis of rib fractures. The two modalities were compared in terms of effectiveness based on simple radiographic readings and US examination results. We also investigated the factors that influenced the effectiveness of US examination. Rib fractures were detected on radiography in 69 patients (34.3%) but not in 132 patients. Rib fractures were diagnosed by using US examination in 160 patients (84.6%). Of the 132 patients who showed no rib fractures on radiography, 92 showed rib fractures on US. Among the 69 patients of rib fracture detected on radiography, 33 had additional rib fractures detected on US. Of the patients, 76 (37.8%) had identical radiographic and US results, and 125 (62.2%) had fractures detected on US that were previously undetected on radiography or additional fractures detected on US. Age, duration until US examination, and fracture location were not significant influencing factors. However, in the group without detected fractures on radiography, US showed a more significant effectiveness than in the group with detected fractures on radiography ( P =0.003). US examination could detect unnoticed rib fractures on simple radiography. US examination is especially more effective in the group without detected fractures on radiography. More attention should be paid to patients with chest trauma who have no detected fractures on radiography.
M1A2 Adjunct Analysis (POSNOV Volume)
1989-12-01
MD 20814-2797 Director 2 U.S. Army Materiel Systems Analysis Activity ATTN: AMXSY-CS, AMXSY-GA Aberden Proving Grounds , MD 21005-5071 U.S. Army...Leonard Wood, MO Commander U.S. Army Ordnance Center & School ATTN: ATSL-CD-CS Aberdeen Proving Ground , MD 21005 Commander 2 U.S. Army Soldier Support...NJ Commander U.S. Army Test and Evaluation Command ATrN: AMSTE-CM-R Aberdeen Proving Ground , MD 21005 Commander U.S. Army Tank Automotive Command
2016-10-01
ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop ...ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory...Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section 5a. CONTRACT NUMBER
The Zwicky Transient Facility (ZTF) begins
NASA Astrophysics Data System (ADS)
Kulkarni, S. R.
2018-02-01
S. R. Kulkarni on behalf of the Zwicky Transient Facility (ZTF) announces the first confirmed results from the project. ZTF is led by the California Institute of Technology, US and includes IPAC, US; Los Alamos National Laboratory, US; University of Maryland, US; University of Wisconsin at Milwaukee, US; University of Washington, US; Oskar-Klein Center of the University of Stockholm, Sweden; DESY and Humboldt University of Berlin, Germany; Weizmann Institute of Science, Israel; and the University System of Taiwan, Taiwan.
ERIC Educational Resources Information Center
Van Horne, Sam; Lin, Shuhui; Anson, Matthew; Jacobson, Wayne
2018-01-01
International students face challenges that their U.S. classmates rarely encounter, but few studies examine specific ways in which undergraduate experiences of international students compare to those of their U.S. classmates. This study examines U.S. and international student responses to an undergraduate survey administered at nine U.S. research…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-18
... DEPARTMENT OF AGRICULTURE Rural Housing Service U.S. Department of Agriculture Multi-Family...-Discrimination Statement The U.S. Department of Agriculture (USDA) prohibits discrimination against its customers... letter to us by mail at U.S. Department of Agriculture, Director, Office of Adjudication, 1400...
Defense.gov Special Report: Unified Combatant Commands
in support of U.S. strategic objectives. Their mission is to maintain command and control of U.S coverage and more information. Unified Combatant Command strategic map U.S. Northern Command NORTHCOM U.S U.S. Strategic Command STRATCOM . Main Menu Home Today in DOD About DOD Leaders Biographies
Natural Hazards Observer. Volume XXV, Number 3
2001-01-01
National Science Foundation , Federal Emergency Management Agency, National Oceanic and Atmospheric Administration, U.S. (Geological Survey, U.S. Army Corps of Engineers, U.S. Environmental Protection Agency, U.S. Department of Transportation, U.S. Bureau of Reclamation, National Aeronautics and Space Administration, the Institute for Business and Home Safety, and the Public Entity Risk
Natural Hazards Observer, Volume XXV No. 2, November 2000
2000-11-01
National Science Foundation , Federal Emergency Management Agency, National Oceanic and Atmospheric Administration, U.S. Geological Survey, U.S. Army Corps of Engineers, U.S. Environmental Protection Agency, U.S. Department of Transportation, U.S. Bureau of Reclamation, National Aeronautics and Space Administration, the Institute for Business and Home Safety, and the Public Entity Risk
32 CFR 761.10 - Persons: Group authorizations.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Airspace Reservation. (b) Military members of the U.S. Armed Forces or U.S. civil service employees of the... military members of the U.S. Armed Forces and U.S. citizen dependents of U.S. civil service employees... 32 National Defense 5 2011-07-01 2011-07-01 false Persons: Group authorizations. 761.10 Section...
32 CFR 761.10 - Persons: Group authorizations.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Airspace Reservation. (b) Military members of the U.S. Armed Forces or U.S. civil service employees of the... military members of the U.S. Armed Forces and U.S. citizen dependents of U.S. civil service employees... 32 National Defense 5 2010-07-01 2010-07-01 false Persons: Group authorizations. 761.10 Section...
Status of the Navy Strategic Documents Command Directory Our Ships Fact Files Today in Naval History Defense.gov U.S. Army U.S. Air Force U.S. Marine Corps U.S. Coast Guard Naval History & Heritage Command Ships Fact Files Today in Naval History Contact Us Command Addresses (SNDL) FAQ Leadership Secretary of
31 CFR 510.310 - U.S. financial institution.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false U.S. financial institution. 510.310 Section 510.310 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... Definitions § 510.310 U.S. financial institution. The term U.S. financial institution means any U.S. entity...
31 CFR 510.310 - U.S. financial institution.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false U.S. financial institution. 510.310 Section 510.310 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... Definitions § 510.310 U.S. financial institution. The term U.S. financial institution means any U.S. entity...
Joint Chiefs of Staff > Media > Photos
U.S. Army Gen. Curtis M. Scaparrotti, left, Commander of U.S. European Command and Supreme Allied , Commander of U.S. European Command and Supreme Allied Commander, Europe; speaks after receiving the . U.S. Army Gen. Curtis M. Scaparrotti, Commander of U.S. European Command and Supreme Allied Commander
31 CFR 510.310 - U.S. financial institution.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false U.S. financial institution. 510.310 Section 510.310 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE... Definitions § 510.310 U.S. financial institution. The term U.S. financial institution means any U.S. entity...
THE BENEFITS OF WETLANDS: THE UPPER HALFWAY CREEK PROJECT
Researchers from the U.S. EPA are working in collaboration with U.S. Geological Survey and the U.S. Fish and Wildlife Services on this project. Upper Halfway Creek marsh is a constructed wetland managed by the U.S. Fish and Wildlife Service. This project will assist the U.S. EP...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-15
... Options Clearing Corporation and NYSE Liffe US LLC in Connection With NYSE Liffe US LLC's Transition to... Services Agreement (``Clearing Agreement'') between OCC and NYSE Liffe US LLC (``NYSE Liffe US'') to make changes to the Clearing Agreement in connection with NYSE Liffe US' transition to electronic vault...
ERIC Educational Resources Information Center
Jones, Andee
2014-01-01
Censorship, says Australian political theorist John Keane (1991), can "echo within us, take up residence within ourselves, spying on us, a private amanuensis who reminds us never to go too far... It makes us zip our lips, tremble and think twice" (p. 39). It can also make us sick. The author states that this is her argument here: that,…
Educational inequalities in self-rated health across US states and European countries.
Präg, Patrick; Subramanian, S V
2017-07-01
The US shows a distinct health disadvantage when compared to other high-income nations. A potential lever to reduce this disadvantage is to improve the health situation of lower socioeconomic groups. Our objective is to explore how the considerable within-US variation in health inequalities compares to the health inequalities across other Western countries. Representative survey data from 44 European countries and the US federal states were obtained from the fourth wave of the European Values Study (EVS) and the 2008 wave of the Behavioral Risk Factor Surveillance System. Using binary logistic regression, we analyze different forms of educational inequalities in self-rated health (SRH), adjusted for age and sex. The extent of educational inequalities in SRH varies considerably over European countries and US states; with US states in general showing greater inequality, however, differences between US states and European countries are less clear than commonly assumed. The US has considerable differences in educational inequalities in SRH across geographic locations. To understand the reasons for the US health disadvantage, comparative research has to take into account the vast variation in health inequalities within the US.
Li, J; Guo, X J; Ding, X L; Lyu, B M; Xiao, J; Sun, Q L; Li, D S; Zhang, W F; Zhou, J C; Li, C P; Yang, R C
2018-02-14
Objective: To assess the feasibility of HEAD-US scale in the clinical application of hemophilic arthropathy (HA) and propose an optimized ultrasound scoring system. Methods: From July 2015 to August 2017, 1 035 joints ultrasonographic examinations were performed in 91 patients. Melchiorre, HEAD-US (Hemophilic Early Arthropathy Detection with UltraSound) and HEAD-US-C (HEAD-US in China) scale scores were used respectively to analyze the results. The correlations between three ultrasound scales and Hemophilia Joint Health Scores (HJHS) were evaluated. The sensitivity differences of the above Ultrasonic scoring systems in evaluation of HA were compared. Results: All the 91 patients were male, with median age of 16 (4-55) years old, including 86 cases of hemophilia A and 5 cases hemophilia B. The median ( P 25 , P 75 ) of Melchiorre, HEAD-US and HEAD-US-C scores of 1 035 joints were 2(0,6), 1(0,5) and 2(0,6), respectively, and the correlation coefficients compared with HJHS was 0.747, 0.762 and 0.765 respectively, with statistical significance ( P <0.001). The positive rates of Melchiorre, HEAD-US-C and HEAD-US scale score were 63.0% (95% CI 59.7%-65.9%), 59.5% (95% CI 56.5%-62.4%) and 56.6% (95% CI 53.6%-59.6%) respectively, and the difference was statistically significant ( P <0.001). Even for 336 cases of asymptomatic joints, the positive rates of Melchiorre, HEAD-US-C and HEAD-US scale score were 25.0% (95% CI 20.6%-29.6%), 17.0% (95% CI 12.6%-21.1%) and 11.9% (95% CI 8.4%-15.7%) respectively, and the difference was statistically significant ( P <0.001). There were significant changes ( P <0.05) in the ultrasonographic score of HA before and after onset of hemorrhage in 107 joints of 40 patients. The difference in variation amplitude of HEAD-US-C scores and HEAD-US scores before and after joint bleeding was statistically significant ( P <0.001). Conclusion: Compared with Melchiorre, there were similar good correlations between HEAD-US, HEAD-US-C and HJHS. HEAD-US ultrasound scoring system is quick, convenient and simple to use. The optimized HEAD-US-C scale score is more sensitive than HEAD-US, especially for patients with HA who have subclinical state, which make up for insufficiency of sensitivity in HEAD-US scoring system.
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Congressional Black Caucus meets with NASA
2010-01-13
NASA Administrator Charles Bolden, space shuttle crew STS-129 and members of the Congressional Black Caucus pose for a group photo at the Capitol Building, Wednesday, Jan. 13, 2010, in Washington. Back row from left to right: U.S. Rep Donna Edwards (D-MD), U.S. Rep Diane Watson (D-CA), NASA Administrator Charles Bolden, astronauts Leland Melvin, Mike Foreman, Robert Satcher, Barry Wilmore, Randy Breznik, and U.S. Rep Mel Watt (D-NC). Front row from left to right: U.S. Rep Robert Scott (D-VA), U.S. Rep. Corrine Brown (D-Fla), U.S. Rep. Barbara Lee (D-CA), U.S. Rep. Donna Christensen (D-VI) and U.S. Rep. Donald Payne (D-NJ). The crew of STS-129 presented the CBC with a montage commemorating their mission. Photo Credit: (NASA/Paul E. Alers)
AmeriFlux US-SCg Southern California Climate Gradient - Grassland
DOE Office of Scientific and Technical Information (OSTI.GOV)
Goulden, Mike
This is the AmeriFlux version of the carbon flux data for the site US-SCg Southern California Climate Gradient - Grassland. Site Description - Half hourly data are available at https://www.ess.uci.edu/~california/. This site is one of six Southern California Climate Gradient flux towers operated along an elevation gradient (sites are US-SCg, US-SCs, US-SCf, US-SCw, US-SCc, US-SCd). This site is a grassland that was historically dominated by exotic annuals and that underwent restoration with a focus on native bunch grasses in the 2010s. The site has historically burned every 10-20 years, with a wildfire in October 2007. The restoration involved several yearsmore » of mowing and herbicide application to suppress exotics followed by dense planting of Nasella bunch grasses.« less
Cultural Competency in Nursing Research.
Cope, Diane G
2015-05-01
According to data from the U.S. Census Bureau (2010), the demographics of the United States will change dramatically in the next 50 years. Non-Caucasians will more than double from 116.2 million in 2012 to 241.3 million by 2060, representing 57% of the U.S. population (U.S. Census Bureau, 2010). The Asian population also is expected to double in the next five years and comprise 8% of the U.S. population (U.S. Census Bureau, 2012). The United States also is becoming an aging population. By 2060, about one in five residents will be aged 65 years and older (U.S. Census Bureau, 2012). Individuals aged 85 years and older will more than triple to 18.2 million and represent 4% of the U.S. population (U.S. Census Bureau, 2012). .
Cost-benefit analysis of first-generation antihistamines in the treatment of allergic rhinitis.
Sullivan, Patrick W; Follin, Sheryl L; Nichol, Michael B
2004-01-01
The majority of individuals with allergic rhinitis in the US take first-generation antihistamines (FGAs). Although FGAs have been proven effective in alleviating allergic rhinitis symptoms, they have been associated with an increased risk of motor vehicle, aviation and occupational injuries and deaths, reduced productivity and impaired learning. The objective of this analysis was to quantify the total costs and benefits of FGA use in the US from the societal perspective. We used a decision-analytic model to quantify the annual societal costs and benefits of treatment with FGAs compared with the hypothetical alternative of no treatment for the population of individuals with allergic rhinitis and taking FGAs in the US in 2001. The benefit associated with FGA use was estimated using the willingness-to-pay framework and projected to the US population using published estimates of the prevalence of allergic rhinitis. The costs of FGA-associated sedation included lost productivity and the direct and indirect cost of unintentional injuries (including motor vehicle, occupational, public and home injuries and fatalities). The incidence of injuries and fatalities associated with FGA use was estimated using the risk of injury attributable to the sedentary effects of FGAs in the allergic rhinitis population. To evaluate uncertainty in the model assumptions, a probabilistic sensitivity analysis was conducted using Bayesian second-order Monte Carlo simulation. Costs and benefits are expressed in 2001 US dollars, using a 3% discount rate. Based on current utilisation, the total societal benefit (95% credible interval) associated with the use of FGAs for the treatment of allergic rhinitis was US 7.7 billion dollars (US 1.3 billion dollars to US 21 billion dollars). The societal cost of purchasing FGAs was only US 697 million dollars. However, the societal cost of FGA-associated sedation was US 11.3 billion dollars (US 2.4 billion dollars to US 50.8 billion dollars). The annual societal net benefit of FGA use for the treatment of allergic rhinitis in the US was -US4.2 billion dollars (-US 36 billion dollars to +US 0.296 billion dollars). The net benefit was negative in 97% of the 10,000 Monte Carlo simulations. The societal benefits of FGA use in alleviating the symptoms of allergic rhinitis are significant. However, based on the assumptions, probability distributions and parameter estimate ranges used in the current model, it is very likely that the costs associated with sedation exceed the benefits of FGA use in the US. The cost of FGA-associated sedation is comparable to estimates of the cost of all medical care expenditures on respiratory conditions in the US (US 12.1 billion dollars to US 31.3 billion dollars) [1996 values] and provides compelling evidence of the economic burden of sedation associated with FGA use.
and in partnership with the U.S. Departments of Agriculture, Commerce, Defense, Education, Housing and United States Advisory Council on Historic Preservation logo U.S. Department of Agriculture logo U.S
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Constenla, Dagna O
2015-11-01
A decision-analytic model was constructed to evaluate the economic impact of post-introduction pneumococcal conjugate vaccine (PCV) programs in Ecuador, Honduras, and Paraguay from the societal perspective. Hypothetical birth cohorts were followed for a 20-year period in each country. Estimates of disease burden, vaccine effectiveness, and health care costs were derived from primary and secondary data sources. Costs were expressed in 2014 US$. Sensitivity analyses were performed to assess the impact of model input uncertainties. Over the 20 years of vaccine program implementation, the health care costs per case ranged from US$ 764 854 to more than US$ 1 million. Vaccination prevented more than 50% of pneumococcal cases and deaths per country. At a cost of US$ 16 per dose, the cost per disability-adjusted life year (DALY) averted for the 10-valent PCV (PCV10) and the 13-valet PCV (PCV13) ranged from US$ 796 (Honduras) to US$ 1 340 (Ecuador) and from US$ 691 (Honduras) to US$ 1 166 (Ecuador) respectively. At a reduced price (US$ 7 per dose), the cost per DALY averted ranged from US$ 327 (Honduras) to US$ 528 (Ecuador) and from US$ 281 (Honduras) to US$ 456 (Ecuador) for PCV10 and PCV13 respectively. Several model parameters influenced the results of the analysis, including vaccine price, vaccine efficacy, disease incidence, and costs. The economic impact of post-introduction PCV needs to be assessed in a context of uncertainty regarding changing antibiotic resistance, herd and serotype replacement effects, differential vaccine prices, and government budget constraints.
2011-01-01
Dawn.Nida@us.army.mil) Joshua Magnone (Joshua.Magnone@us.army.mil) Andre Senecal (Andy.Senecal@us.army.mil) ISSN 1477-3155 Article type Research Submission...Dawn.Nida@us.army.mil; Joshua Magnone - Joshua.Magnone@us.army.mil; Andre Senecal - Andy.Senecal@us.army.mil *Corresponding Author 2...Biol Eng 2007, 1:doi10.1186/1754-1611-1-2. 12. Senecal A, Magnone J, Marek P, Senecal K: Development of functional nanofibrous membrane assemblies
U.S. Economic Strategy in Shaping Mexico - Living Happily Ever NAFTA.
1998-05-09
DOCTRINE IN THE HOUSE? 21 A U.S. Peso Crisis? 21 U.S. Promotion of Labor Reform 24 v U.S. STRATEGY - LINKING ENDS, WAYS AND MEANS 26 CONCLUSION...part to devaluation of the peso . Percentage changes calculated in local currency- Merchandise trade 5 Source: U.S. Department of Commerce and U.S...Mexico’s economic or political stability. A similar rationale can be applied to understanding the motive for U.S. assistance during the Peso Crisis of
Bigfoot or Big Mistake: Is CBP’s Expanding Footprint Helping or Hurting Homeland Security
2017-03-31
message. Since its founding in 1789, the U.S. Customs Service has guarded the U.S. ports of entry and collected tariffs on goods coming into the United...a nation’s innocence. Immediately after the attacks, Commissioner Bonner knew that a change in the mission of U.S. Customs Service was essential to...Department of Homeland Security (DHS). This included the U.S. Customs Service , U.S. Border Patrol, and U.S. Coast Guard. Title IV of the Act created
International energy indicators
NASA Astrophysics Data System (ADS)
Rosoi, E., Jr.
1982-01-01
Data are presented under the following headings: world crude oil production, OPEC crude oil productive capacity; world crude oil and refined product inventory levels; and oil consumption in the OECD countries. The USSR crude oil production and exports; free world and US nuclear electricity generation; US domestic oil supply; US gross imports of crude oil and products; landed cost of Saudi crude, current and 1974 dollars; US coal trade; US natural gas trade; summary of US merchandise trade; and energy/GNP ratio data are also included.
Finnoff, Jonathan T; Berkoff, David; Brennan, Fred; DiFiori, John; Hall, Mederic M; Harmon, Kimberly; Lavallee, Mark; Martin, Sean; Smith, Jay; Stovak, Mark
2015-01-01
The following sports ultrasound (SPORTS US) curriculum is a revision of the curriculum developed by the American Medical Society for Sports Medicine (AMSSM) in 2010. Several changes have been made to the curriculum with the primary aim of providing a pathway by which a sports medicine fellow can obtain sufficient SPORTS US training to become proficient in the core competencies of SPORTS US. The core competencies of SPORTS US are outlined in the learning objectives section of this document. The term "SPORTS US" was purposefully chosen rather than "musculoskeletal ultrasound" (MSK US) because it was recognized by the panel that the evolving field of SPORTS US encompasses non-MSK applications of ultrasound such as the FAST examination (focused assessment with sonography for trauma). Although the SPORTS US core competencies in this curriculum are all MSK in nature, they represent the minimum SPORTS US knowledge a sports medicine fellow should acquire during fellowship. However, additional training in more advanced MSK and non-MSK applications of ultrasound can be provided at the fellowship director's discretion. Completion of this SPORTS US curriculum fulfills the American Institute of Ultrasound in Medicine's (AIUM) requirements to perform an MSK US examination and the prerequisites for the American Registry for Diagnostic Medical Sonography's (ARDMS) MSK sonography certification examination.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stewart, R.J.
About 200 US flag tankers operate between US ports; the import trade consists of 30-40 more US tankers and 600-700 foreign tankers. US ships have 50% as many spills per port call as Liberian tankers and 20-33% as many as foreign tankers as a whole. There is mounting evidence that ships are prone to have a rather constant number of spills per year irrespective of variations in port call exposure. When spill incidence is measured per ship time, the US tanker margin over foreign fleets is only 2-3 instead of 3-6. For 1973-1975, 76% of all US tanker spills weremore » <100 gal, compared with 65% of all flag of convenience spills. The probability of no tanker losses in a one-year period in US waters is only 0.22. One-half the losses can be expected to occur in conditions favorable to a spill in coastal waters. In any given year, the US tanker fleet of 235 vessels >1000 gross registered tonnage can be expected to have about 100 spills in US waters, while foreign flag ships contribute another 250 spills. The largest US tanker spill in a one-year period is <5000 gal; the median value for the largest spill from foreign tankers is closer to 50,000-100,000 gal.« less
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-11
...Notice is hereby given that two complaints were filed with the U.S. International Trade Commission on June 3, 2011, under section 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of OSRAM GmbH of Germany. Both complaints allege violations of section 337 based upon the importation into the United States, the sale for importation, and the sale within the United States after importation of certain lighting-emitting diodes and products containing same by reason of infringement of certain claims of U.S. Patents. The first complaint asserts U.S. Patent No. 6,812,500 (``the `500 patent''); U.S. Patent No. 7,078,732 (``the `732 patent''); U.S. Patent No. 7,126,162 (``the `162 patent''); U.S. Patent No. 7,345,317 (``the `317 patent''); U.S. Patent No. 7,629,621 (``the `621 patent''); U.S. Patent No. 6,459,130 (``the `130 patent''); U.S. Patent No. 6,927,469 (``the `469 patent''); U.S. Patent No. 7,199,454 (``the `454 patent''); and U.S. Patent No. 7,427,806 (``the `806 patent''). The second complaint asserts U.S. Patent No. 6,849,881 (``the `881 patent''); U.S. Patent No. 6,975,011 (``the `011 patent''); U.S. Patent No. 7,106,090 (``the `090 patent''); U.S. Patent No. 7,151,283 (``the `283 patent''); and U.S. Patent No. 7,271,425 (``the `425 patent'') as well as the `500 patent, `732 patent, `162 patent, `621 patent, `130 patent, `469 patent, and `454 patent. Each complaint further alleges that an industry in the United States exists as required by subsection (a)(2) of section 337. The complainant requests that the Commission institute the two investigations and, after the investigation, issue an exclusion order and cease and desist orders. Letters regarding the possible consolidation of investigations stemming from these complaints were received on June 21, June 22, and June 29, 2011.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-11
...Notice is hereby given that two complaints were filed with the U.S. International Trade Commission on June 3, 2011, under section 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of OSRAM GmbH of Germany. Both complaints allege violations of section 337 based upon the importation into the United States, the sale for importation, and the sale within the United States after importation of certain light-emitting diodes and products containing same by reason of infringement of certain claims of U.S. Patents. The first complaint asserts U.S. Patent No. 6,812,500 (``the `500 patent''); U.S. Patent No. 7,078,732 (``the `732 patent''); U.S. Patent No. 7,126,162 (``the `162 patent''); U.S. Patent No. 7,345,317 (``the `317 patent''); U.S. Patent No. 7,629,621 (``the `621 patent''); U.S. Patent No. 6,459,130 (``the `130 patent''); U.S. Patent No. 6,927,469 (``the `469 patent''); U.S. Patent No. 7,199,454 (``the `454 patent''); and U.S. Patent No. 7,427,806 (``the `806 patent''). The second complaint asserts U.S. Patent No. 6,849,881 (``the `881 patent''); U.S. Patent No. 6,975,011 (``the `011 patent''); U.S. Patent No. 7,106,090 (``the `090 patent''); U.S. Patent No. 7,151,283 (``the `283 patent''); and U.S. Patent No. 7,271,425 (``the `425 patent'') as well as the `500 patent, `732 patent, `162 patent, `621 patent, `130 patent, `469 patent, and `454 patent. Each complaint further alleges that an industry in the United States exists as required by subsection (a)(2) of section 337. The complainant requests that the Commission institute the two investigations and, after the investigation, issue an exclusion order and cease and desist orders. Letters regarding the possible consolidation of investigations stemming from these complaints were received on June 21, June 22, and June 29, 2011.
Reinstatement after human feature-positive discrimination learning.
Franssen, Mathijs; Claes, Nathalie; Vervliet, Bram; Beckers, Tom; Hermans, Dirk; Baeyens, Frank
2017-04-01
In two experiments, using an online conditioned suppression task, we investigated the possibility of reinstatement of extinguished feature-target compound presentations after sequential feature-positive discrimination training in humans. Furthermore, given a hierarchical account of Pavlovian modulation (e.g., Bonardi, 1998; Bonardi and Jennings, 2009), we predicted A-US reinstatement to be stronger than US-only reinstatement. In Experiment 1, participants learned a sequential feature-positive discrimination (X→A + |A - ), which was subsequently extinguished (X→A - ). During the following reinstatement phase, group US-only received US-only presentations (not signalled), group A-US received A-US presentations, and the Control group received exposure to the context, but no CSs or USs, for an equal amount of time. Reinstatement of differential X→A/A responding was observed in the US-only group but not in the Control or A-US groups. Although differential X→A/A responding was not significant in group A-US, responding to the X→A compound was significantly stronger compared to that in group US-only. Hence, it could be the case the group A-US showed stronger reinstatement, but that differential responding was abolished due to excitation gained by A. Experiment 2 was set up to circumvent the acquired excitation of A by testing transfer of the feature after A-US reinstatement to a different target, B. Participants acquired two discriminations, X→A/A and Y→B/B, of which X→A was then extinguished. Subsequently, group A-US received reinforced presentations of A during a reinstatement phase while group Control received exposure to the context. Final testing of the novel X→B compound was hypothesized to show higher responding in group A-US than in group Control, but findings of this approach were limited due to acquired equivalence and/or perceptual factors causing a secondary extinction effect. We conclude to have obtained clear evidence in favour of reinstatement of differential responding after human Feature-Positive discrimination training and subsequent compound extinction, but no evidence in favour of A-US presentations being a stronger trigger for reinstatement than are US-only presentations. Copyright © 2017 Elsevier B.V. All rights reserved.
Feldman, Steven R; Foster, Shonda A; Zhu, Baojin; Burge, Russel; Al Sawah, Sarah; Goldblum, Orin M
2017-12-01
BACKGROUND: Newer psoriasis treatments can achieve greater levels of efficacy than older systemic therapies; however, current psoriasis costs are substantial. We sought to estimate costs per additional responder associated with ixekizumab and etanercept, versus placebo, using efficacy data from phase 3 clinical trials (UNCOVER-2 and UNCOVER-3). METHODS: In UNCOVER-2/UNCOVER-3, patients received subcutaneous placebo, etanercept 50 mg twice weekly (BIW), or ixekizumab one 80 mg injection every 2 weeks (Q2W) after a 160-mg starting dose. Twelve-week induction-phase Psoriasis Area and Severity Index (PASI) 75, PASI 90, and PASI 100 response rates for ixekizumab, etanercept, and placebo were obtained from pooled data from the overall and United States (US) subgroup intention-to-treat (ITT) populations, and used to calculate numbers needed to treat (NNTs) to achieve one additional PASI 75, PASI 90, or PASI 100 response for ixekizumab Q2W and etanercept BIW versus placebo. Twelve-week drug costs per patient were calculated based on the UNCOVER-2/UNCOVER-3 dosing schedule and wholesale acquisition costs. Mean costs per additional responder for PASI 75, PASI 90, and PASI 100 for each treatment versus placebo were calculated for pooled UN-COVER-2/UNCOVER-3 overall and US subgroup ITT populations. RESULTS: Pooled overall ITT population: costs per additional PASI 75, PASI 90, or PASI 100 responder were US $37,540, US $46,299, or US $80,710 for ixekizumab Q2W and US $57,533, US $120,720, or US $404,695 for etanercept BIW, respectively. US subgroup ITT population: costs per additional PASI 75, PASI 90, or PASI 100 responder were US $38,165, US $49,740, or US $93,536 for ixekizumab Q2W and US $69,580, US $140,881, or US $631,875 for etanercept BIW, respectively. CONCLUSIONS: Twelve-week costs per additional responder were lower for ixekizumab Q2W than for etanercept BIW across all levels of clearance (PASI 75, PASI 90, and PASI 100) in the pooled UNCOVER-2/UNCOVER-3 overall and US subgroup ITT populations.
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Ensuring Academic Standards in US Higher Education
ERIC Educational Resources Information Center
Dill, David D.
2014-01-01
The most recent research on college-student learning in the US by respected scholars such as Richard Arum, Josipa Roksa, and Ernest Pascarella suggests that the nation's means of ensuring academic standards in US colleges and universities are not working effectively. Like US K-12 education and health care, the US higher education system is…
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31 CFR 800.226 - U.S. business.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false U.S. business. 800.226 Section 800.226... FOREIGN PERSONS Definitions § 800.226 U.S. business. The term U.S. business means any entity, irrespective... subsidiary is a U.S. business. Corporation A and its branch or subsidiary is each also a foreign person...
31 CFR 800.226 - U.S. business.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false U.S. business. 800.226 Section 800.226... FOREIGN PERSONS Definitions § 800.226 U.S. business. The term U.S. business means any entity, irrespective... subsidiary is a U.S. business. Corporation A and its branch or subsidiary is each also a foreign person...
31 CFR 800.226 - U.S. business.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false U.S. business. 800.226 Section 800.226... FOREIGN PERSONS Definitions § 800.226 U.S. business. The term U.S. business means any entity, irrespective... subsidiary is a U.S. business. Corporation A and its branch or subsidiary is each also a foreign person...
Nothing about Us without Us: Art Education's Disservice to Disabled People
ERIC Educational Resources Information Center
Derby, John
2013-01-01
The disability rights movement slogan, "nothing about us without us," has been trumpeted with such fervor that it is nearly a cliché. However, readers have never seen this phrase in "Studies in Art Education." Almost "nothing about us" has appeared in the pages of "Studies" or other major journals in the…
Liu, Jianxin; Shang, Tingting; Wang, Fengjuan; Cao, Yang; Hao, Lan; Ren, JianLi; Ran, Haitao; Wang, Zhigang; Li, Pan; Du, Zhiyu
2017-01-01
The commonly used ultrasound (US) molecular probes, such as targeted microbubbles and perfluorocarbon emulsions, present a number of inherent problems including the conflict between US visualization and particle penetration. This study describes the successful fabrication of phase changeable folate-targeted perfluoropentane nanodroplets (termed FA-NDs), a novel US molecular probe for tumor molecular imaging with US. Notably, these FA-NDs can be triggered by low-intensity focused US (LIFU) sonication, providing excellent US enhancement in B-mode and contrast-enhanced US mode in vitro. After intravenous administration into nude mice bearing SKOV3 ovarian carcinomas, 1,1'-dioctadecyl-3,3,3',3' -tetramethylindotricarbocya-nine iodide-labeled FA-NDs were found to accumulate in the tumor region. FA-NDs injection followed by LIFU sonication exhibited remarkable US contrast enhancement in the tumor region. In conclusion, combining our elaborately developed FA-NDs with LIFU sonication provides a potential protocol for US molecular imaging in folate receptor-overexpressing tumors.
Liu, Jianxin; Shang, Tingting; Wang, Fengjuan; Cao, Yang; Hao, Lan; Ren, JianLi; Ran, Haitao; Wang, Zhigang; Li, Pan; Du, Zhiyu
2017-01-01
The commonly used ultrasound (US) molecular probes, such as targeted microbubbles and perfluorocarbon emulsions, present a number of inherent problems including the conflict between US visualization and particle penetration. This study describes the successful fabrication of phase changeable folate-targeted perfluoropentane nanodroplets (termed FA-NDs), a novel US molecular probe for tumor molecular imaging with US. Notably, these FA-NDs can be triggered by low-intensity focused US (LIFU) sonication, providing excellent US enhancement in B-mode and contrast-enhanced US mode in vitro. After intravenous administration into nude mice bearing SKOV3 ovarian carcinomas, 1,1′-dioctadecyl-3,3,3′,3′ -tetramethylindotricarbocya-nine iodide-labeled FA-NDs were found to accumulate in the tumor region. FA-NDs injection followed by LIFU sonication exhibited remarkable US contrast enhancement in the tumor region. In conclusion, combining our elaborately developed FA-NDs with LIFU sonication provides a potential protocol for US molecular imaging in folate receptor-overexpressing tumors. PMID:28184161
Dillman, Jonathan R; Smith, Ethan A; Sanchez, Ramon; DiPietro, Michael A; Dehkordy, Soudabeh Fazeli; Adler, Jeremy; DeMatos-Maillard, Vera; Khalatbari, Shokoufeh; Davenport, Matthew S
2016-04-01
There is a paucity of published literature describing ultrasound (US)-US and US-MR enterography (MRE) inter-radiologist agreement in pediatric small bowel Crohn disease. To prospectively assess US-US and US-MRE inter-radiologist agreement in pediatric small bowel Crohn disease. Institutional Review Board approval and informed consent/assent were obtained for this HIPAA-compliant prospective cohort study of children with newly diagnosed distal small bowel Crohn disease (July 2012 to December 2014). Enrolled subjects (n = 29) underwent two small bowel US examinations performed by blinded independent radiologists both before and at multiple time points after initiation of medical therapy (231 unique US examinations, in total); 134 US examinations were associated with concurrent MRE. The MRE examination was interpreted by a third blinded radiologist. The following was documented on each examination: involved length of ileum (cm); maximum bowel wall thickness (mm); amount of bowel wall and mesenteric Doppler signal, and presence of stricture, penetrating disease and/or abscess. Inter-radiologist agreement was assessed with single-measure, three-way, mixed-model intra-class correlation coefficients (ICC) and prevalence-adjusted, bias-adjusted kappa statistics (κ). Numbers in brackets are 95% confidence intervals. Ultrasound-US agreement was moderate for involved length (ICC: 0.41 [0.35-0.49]); substantial for maximum bowel wall thickness (ICC: 0.67 [0.64-0.70]); moderate for bowel wall Doppler signal (ICC: 0.53 [0.48-0.59]); slight for mesenteric Doppler signal (ICC: 0.25 [0.18-0.42]), and moderate to almost perfect for stricture (κ: 0.54), penetrating disease (κ: 0.80), and abscess (κ: 0.96). US-MRE agreement was moderate for involved length (ICC: 0.42 [0.37-0.49]); substantial for maximum bowel wall thickness (ICC: 0.66 [0.65-0.69]), and substantial to almost perfect for stricture (κ: 0.61), penetrating disease (κ: 0.72) and abscess (κ: 0.88). Ultrasound-US agreement was similar to US-MRE agreement for assessing pediatric small bowel Crohn disease. Discrepancies in US-US and US-MRE reporting question the utility of US as an accurate, reproducible radiologic biomarker for assessing response to medical therapy and disease-related complications.
What Can We Learn from Hugoniot Temperature as a Function of Shock Velocity?
NASA Astrophysics Data System (ADS)
LI, M.; Jeanloz, R.
2015-12-01
Shock-wave experiments traditionally rely on impact techniques, whereby measured shock velocity (US) can be related to material velocity (up), determined from the impact velocity (= 2up for a symmetric impact), and resulting in the empirically observed linear US-up equation of state: US = c0 + s up. Modern experiments relying on laser-driven compression have the advantage of reaching higher pressures than laboratory impact experiments, but up is typically not determined; instead, Hugoniot temperature (TH) and shock velocity are more readily measured. Assuming a linear US-up equation of state and that the Grüneisen parameter has the volume dependence g(V) = g0 (V/V0), measurements of the Hugoniot temperature as a function of shock velocity provide constraints on the specific heat along the Hugoniot CVH(US) = V0 f(US)[c0 g0 TH - s US dTH/dUS]-1 where the Walsh-Christian (1955) function f(US) = - (US - c0)2 US/(V0 s c0) = TH dSH/dVH gives the entropy change along the Hugoniot (subscripts 0 and H indicate zero-pressure and Hugoniot states, respectively). In this sense, TH(US) measurements are similar to calorimetry experiments. If specific heat and Grüneisen parameter are determined independently (e.g., from wave-velocity measurements and experiments on porous samples), the TH(US) analog to the linear US-up equation of state is TH(US) = {T0 exp(g0 /s) - ò[V0 c0 f(x)/(s x CV)] exp[c0 g0 /(s x)] dx} exp[- c0 g0 /(s US)] where the integration is from x = c0 to x = US. In addition, experiments can be considered with: 1) different initial volume, as in a porous sample; 2) different initial internal energy, as in a sample heated at constant volume; and 3) different initial volume and internal energy, as in a sample initially heated at ambient pressure. From these four initial states, we get four different Hugoniot curves, and can also consider the effect of phase transition latent heat. Temperature as a function of shock velocity may thus be benefit the analysis of melting and other phase transitions with small volume change and finite latent heat.
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Wong, Martin C S; Ching, Jessica Y L; Chan, Victor C W; Sung, Joseph J Y
2015-09-04
Faecal immunochemical tests (FITs) and colonoscopy are two common screening tools for colorectal cancer(CRC). Most cost-effectiveness studies focused on survival as the outcome, and were based on modeling techniques instead of real world observational data. This study evaluated the cost-effectiveness of these two tests to detect colorectal neoplastic lesions based on data from a 5-year community screening service. The incremental cost-effectiveness ratio (ICER) was assessed based on the detection rates of neoplastic lesions, and costs including screening compliance, polypectomy, colonoscopy complications, and staging of CRC detected. A total of 5,863 patients received yearly FIT and 4,869 received colonoscopy. Compared with FIT, colonoscopy detected notably more adenomas (23.6% vs. 1.6%) and advanced lesions or cancer (4.2% vs. 1.2%). Using FIT as control, the ICER of screening colonoscopy in detecting adenoma, advanced adenoma, CRC and a composite endpoint of either advanced adenoma or stage I CRC was US$3,489, US$27,962, US$922,762 and US$23,981 respectively. The respective ICER was US$3,597, US$439,513, -US$2,765,876 and US$32,297 among lower-risk subjects; whilst the corresponding figure was US$3,153, US$14,852, US$184,162 and US$13,919 among higher-risk subjects. When compared to FIT, colonoscopy is considered cost-effective for screening adenoma, advanced neoplasia, and a composite endpoint of advanced neoplasia or stage I CRC.
Deitelzweig, Steve; Luo, Xuemei; Gupta, Kiran; Trocio, Jeffrey; Mardekian, Jack; Curtice, Tammy; Hlavacek, Patrick; Lingohr-Smith, Melissa; Menges, Brandy; Lin, Jay
2018-05-01
In this study, all-cause, stroke/systemic embolism (SE)-related, and major bleeding (MB)-related health-care costs among elderly patients with nonvalvular atrial fibrillation (NVAF) initiating treatment with different oral anticoagulants (OACs) were compared. Patients ≥65 years of age initiating OACs, including apixaban, rivaroxaban, dabigatran, and warfarin, were identified from the Humana Research Database between January 1, 2013, and September 30, 2015. Propensity score matching was used to separately match the different OAC cohorts with the apixaban cohort. All-cause health-care costs and stroke/SE-related and MB-related medical costs per patient per month (PPPM) were compared using generalized linear or 2-part regression models. Compared to apixaban, rivaroxaban was associated with significantly higher all-cause health-care costs (US$2234 vs US$1846 PPPM, P < .001) and MB-related medical costs (US$106 vs US$47 PPPM, P < .001), dabigatran was associated with significantly higher all-cause health-care costs (US$1980 vs US$1801 PPPM, P = .007), and warfarin was associated with significantly higher all-cause health-care costs (US$2386 vs US$1929 PPPM, P < .001), stroke/SE-related medical costs (US$42 vs US$18 PPPM, P < .001), and MB-related medical costs (US$132 vs US$51 PPPM, P < .001). Among elderly patients with NVAF, other OACs were associated with higher all-cause health-care costs than apixaban.
Money well spent: a comparison of hospital operating margin for laparoscopic and open colectomies.
Koopmann, M C; Harms, B A; Heise, C P
2007-10-01
Cost analysis after laparoscopic colectomy has been examined, although reports evaluating the effects of laparoscopy on hospital operating margin are lacking. We compared several cost/revenue measures, including hospital operating margin, between open and laparoscopic colectomies at an academic center. Our cost-accounting database was queried for laparoscopic partial (LPC) and total colectomies (LTC), and open partial (OPC) and total colectomies (OTC) to analyze net revenue, total costs, and total hospital operating margin over a 4-year period. Laparoscopic and open colectomy cases were compared, with mean operating margin as the primary outcome. From July, 2002 through May, 2006, 842 patients were included for analysis with 138 undergoing laparoscopic colectomy. Net revenue was higher in the LTC group compared with open (US dollars 30,300 vs US dollars 26,800 [P = .02]), and lower in the LPC group (US dollars 15,300 vs US dollars 21,300 open [P < .0001]). Total costs were reduced in both the LPC and LTC groups compared with open [US dollars 11,700 vs US dollars 17,600 [P < .0001] and US dollars 18,000 vs US dollars 19,400 [P = .0019], respectively). LPC resulted in a similar HOM (US dollars 3,602) compared with OPC (US dollars 3,647; P = .35). LTC resulted in a higher HOM (US dollars 12,300) compared with OTC (US dollars 7,400; P = .02). LTC generates a significantly higher hospital operating margin than an OTC, although the margins are similar for LPC and OPC.
Role of specimen US for predicting resection margin status in breast conserving therapy.
Moschetta, M; Telegrafo, M; Introna, T; Coi, L; Rella, L; Ranieri, V; Cirili, A; Stabile Ianora, A A; Angelelli, G
2015-01-01
To assess the diagnostic accuracy of specimen ultrasound (US) for predicting resection margin status in women undergoing breast conserving therapy for US-detected cancer, having the histological findings as the reference standard. A total of 132 consecutive patients (age range, 34-87 years; mean, 51 years) underwent breast-conserving surgery for US-detected invasive breast cancer. All surgical specimens underwent US examination. The presence of lesion within the specimen and its distance from the specimen margins were assessed considering a threshold distance between the lesion and specimen margins of 10 mm. US findings were then compared with the pathological ones and specimen US. Sensitivity, specificity, diagnostic accuracy, positive (PPV) and negative predictive values (NPV) for predicting histological margin status were evaluated, having the histological findings as the reference standard. The histological examination detected invasive ductal carcinoma in 96/132 (73%) cases, invasive lobular carcinoma in 32/132 (24%), mucinous carcinoma in 4/132 (3%). The pathological margin analysis revealed 96/132 (73%) negative margins and 36 (27%) close/positive margins. US examination detected all 132 breast lesions within the surgical specimens. 110 (83%) negative margins and 22 (17%) positive margins were found on US. Sensitivity, specificity, diagnostic accuracy, PPV and NPV of 44%, 94%, 80%, 73% and 82%, respectively, were found for specimen US. Specimen US represents a time and cost saving imaging tool for evaluating the presence of US detected-breast lesion within surgical specimen and for predicting the histological margin status.
Man, Xiaoyuan; Ning, Xun-An; Zou, Haiyuan; Liang, Jieying; Sun, Jian; Lu, Xingwen; Sun, Jiekui
2018-01-01
This paper proposes a combined ultrasound (US) and zero-valent iron/EDTA/Air (ZEA) system to remove polycyclic aromatic hydrocarbons (PAHs) from textile dyeing sludge. The removal efficiencies of 16 PAHs using ZEA, US/Air (air injected into the US process), and US/ZEA treatments were investigated, together with the effects of various operating parameters. The enhanced mechanisms of US and the role of reactive oxygen species (ROS) in removing PAHs in the US/ZEA system were explored. Results showed that only 42.5% and 32.9% of ∑16 PAHs were removed by ZEA and US/Air treatments respectively, whereas 70.1% were removed by US/ZEA treatment, (with favorable operating conditions of 2.0 mM EDTA, 15 g/L ZVI, and 1.08 w/cm 3 ultrasonic density). The US/ZEA system could be used with a wide pH range. US led to synergistic improvement of PAHs removal in the ZEA system by enhancing sludge disintegration to release PAHs and promoting ZVI corrosion and oxygen activation. In the US/ZEA system, PAHs could be degraded by ROS (namely OH, O 2 - /HO 2 , and Fe(IV)) and adsorbed by ZVI, during which the ROS made the predominant contribution. This study provides important insights into the application of a US/ZEA system to remove PAHs from sludge. Copyright © 2017 Elsevier Ltd. All rights reserved.
Wong, Martin CS; Ching, Jessica YL; Chan, Victor CW; Sung, Joseph JY
2015-01-01
Faecal immunochemical tests (FITs) and colonoscopy are two common screening tools for colorectal cancer(CRC). Most cost-effectiveness studies focused on survival as the outcome, and were based on modeling techniques instead of real world observational data. This study evaluated the cost-effectiveness of these two tests to detect colorectal neoplastic lesions based on data from a 5-year community screening service. The incremental cost-effectiveness ratio (ICER) was assessed based on the detection rates of neoplastic lesions, and costs including screening compliance, polypectomy, colonoscopy complications, and staging of CRC detected. A total of 5,863 patients received yearly FIT and 4,869 received colonoscopy. Compared with FIT, colonoscopy detected notably more adenomas (23.6% vs. 1.6%) and advanced lesions or cancer (4.2% vs. 1.2%). Using FIT as control, the ICER of screening colonoscopy in detecting adenoma, advanced adenoma, CRC and a composite endpoint of either advanced adenoma or stage I CRC was US$3,489, US$27,962, US$922,762 and US$23,981 respectively. The respective ICER was US$3,597, US$439,513, -US$2,765,876 and US$32,297 among lower-risk subjects; whilst the corresponding figure was US$3,153, US$14,852, US$184,162 and US$13,919 among higher-risk subjects. When compared to FIT, colonoscopy is considered cost-effective for screening adenoma, advanced neoplasia, and a composite endpoint of advanced neoplasia or stage I CRC. PMID:26338314
39 CFR 1.1 - Establishment of the U.S. Postal Service.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 39 Postal Service 1 2011-07-01 2011-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...
39 CFR 1.1 - Establishment of the U.S. Postal Service.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 39 Postal Service 1 2010-07-01 2010-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...
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2016-07-01
ARL-TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance...TR-7729 ● JULY 2016 US Army Research Laboratory US Army Research Laboratory (ARL) Robotics Collaborative Technology Alliance 2014 Capstone...National Robotics Engineering Center, Pittsburgh, PA Robert Dean, Terence Keegan, and Chip Diberardino General Dynamics Land Systems, Westminster
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Climate Change and International Competition: the US Army in the Arctic Environment
2015-05-21
capabilities are evaluated within the domains of the current US doctrinal definition of Doctrine , Organization, Training, Materiel, Leadership and Education...environment. 15. SUBJECT TERMS US Army Cold Weather Doctrine ; US Army Arctic Operational Capability; ULO; Mission Command; Arctic Council; UNCLOS...capabilities are evaluated within the domains of the current US doctrinal definition of Doctrine , Organization, Training, Materiel, Leadership and
2005-06-01
South Korea Samsung Electronics, Suwon, South Korea US Embassy Country Brief, Beijing, China US Consulate General Brief, Hong Kong Joint US... employees . Innovation, leveraged by science and technology (S&T), has created opportunities within the manufacturing sector. This paper summarizes the...productivity, both per hour and per employee . This fact has enabled the US to maintain a labor cost advantage despite the higher wages/benefits paid to US
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...-0077; 4500030115] Endangered and Threatened Wildlife and Plants; 90-Day Findings on Petitions To Delist... to remove the U.S. captive-bred and U.S. captive populations of three antelope species, the scimitar... delisting the U.S. captive animals or U.S. captive-bred members of these species may be warranted. Therefore...
7 CFR 51.1001 - U.S. Combination.
Code of Federal Regulations, 2014 CFR
2014-01-01
...) In this grade the U.S. No. 1 limes shall meet the color requirements of the U.S. No. 1 grade and the U.S. No. 2 limes shall meet the color requirements of the U.S. No. 2 grade: Provided, That lots of... designated as “U.S. Combination, Mixed Color”: And provided further, That lots of limes which fail to meet...
7 CFR 51.1001 - U.S. Combination.
Code of Federal Regulations, 2013 CFR
2013-01-01
...) In this grade the U.S. No. 1 limes shall meet the color requirements of the U.S. No. 1 grade and the U.S. No. 2 limes shall meet the color requirements of the U.S. No. 2 grade: Provided, That lots of... designated as “U.S. Combination, Mixed Color”: And provided further, That lots of limes which fail to meet...
U.S. Cybersecurity Defense Assessment
2013-03-01
Government . The U.S. Army War College is accredited by the Commission on Higher Education of the Middle States Association of Colleges and...progression of America’s cybersecurity defense policies and the subsequent Federal agency roles which have developed within the U.S. government ...of the Army, Department of Defense, or the U.S. Government . U.S. Army War College CARLISLE BARRACKS, PENNSYLVANIA 17013 Abstract
17 CFR Appendix B to Part 43 - Enumerated Physical Commodity Contracts and Other Contracts
Code of Federal Regulations, 2014 CFR
2014-04-01
... Physical Commodity Contracts and Other Contracts Enumerated Physical Commodity Contracts Agriculture ICE Futures U.S. Cocoa ICE Futures U.S. Coffee C Chicago Board of Trade Corn ICE Futures U.S. Cotton No. 2 ICE... Trade Soybean Oil ICE Futures U.S. Sugar No. 11 ICE Futures U.S. Sugar No. 16 Chicago Board of Trade...
17 CFR Appendix B to Part 43 - Enumerated Physical Commodity Contracts and Other Contracts
Code of Federal Regulations, 2013 CFR
2013-04-01
... Commodity Contracts and Other Contracts Enumerated Physical Commodity Contracts Agriculture ICE Futures U.S. Cocoa ICE Futures U.S. Coffee C Chicago Board of Trade Corn ICE Futures U.S. Cotton No. 2 ICE Futures U... Soybean Oil ICE Futures U.S. Sugar No. 11 ICE Futures U.S. Sugar No. 16 Chicago Board of Trade Wheat...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-28
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32 CFR 842.121 - Referring a claim to the US Attorney.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 6 2011-07-01 2011-07-01 false Referring a claim to the US Attorney. 842.121... to the US Attorney. Only HQ USAF/JACC authorizes referral of a claim to the US Attorney. The base SJA...-case basis, HQ USAF/JACC will authorize referral of a case to the US Attorney by telephone. ...
The U.S. Environmental Protection Agency’s (U.S. EPA) mission is to protect human health and the environment. Those not familiar with U.S. EPA’s mission often do not realize that U.S. EPA is a public health agency. In this presentation, Dr. Danelle Lobdell will provid...
39 CFR 1.1 - Establishment of the U.S. Postal Service.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 39 Postal Service 1 2012-07-01 2012-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...
39 CFR 1.1 - Establishment of the U.S. Postal Service.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 39 Postal Service 1 2014-07-01 2014-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...
39 CFR 1.1 - Establishment of the U.S. Postal Service.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 39 Postal Service 1 2013-07-01 2013-07-01 false Establishment of the U.S. Postal Service. 1.1 Section 1.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE POSTAL POLICY (ARTICLE I) § 1.1 Establishment of the U.S. Postal Service. The U.S. Postal Service is...
Holmes, Julia S; Driscoll, Anne K; Heron, Melonie
2015-07-01
We examined the effects of duration of residence and age at immigration on mortality among US-born and foreign-born Hispanics aged 25 and older. We analyzed the National Health Interview Survey-National Death Index linked files from 1997-2009 with mortality follow-up through 2011. We used Cox proportional hazard models to examine the effects of duration of US residence and age at immigration on mortality for US-born and foreign-born Hispanics, controlling for various demographic, socioeconomic and health factors. Age at immigration included 4 age groups: <18, 18-24, 25-34, and 35+ years. Duration of residence was 0-15 and >15 years. We observed a mortality advantage among Hispanic immigrants compared to US-born Hispanics only for those who had come to the US after age 24 regardless of how long they had lived in the US. Hispanics who immigrated as youths (<18) did not differ from US-born Hispanics on mortality despite duration of residence. Findings suggest that age at immigration, rather than duration of residence, drives differences in mortality between Hispanic immigrants and the US-born Hispanic population.
U.S. oil dependence 2014: Is energy independence in sight?
Greene, David L.; Liu, Changzheng
2015-06-10
The importance of reducing U.S. oil dependence may have changed in light of developments in the world oil market over the past two decades. Since 2005, increased domestic production and decreased oil use have cut U.S. import dependence in half. The direct costs of oil dependence to the U.S. economy are estimated under four U.S. Energy Information Administration Scenarios to 2040. The key premises of the analysis are that the primary oil market failure is the use of market power by OPEC and that U.S. economic vulnerability is a result of the quantity of oil consumed, the lack of readilymore » available, economical substitutes and the quantity of oil imported. Monte Carlo simulations of future oil market conditions indicate that the costs of U.S. oil dependence are likely to increase in constant dollars but decrease relative to U.S. gross domestic product unless oil resources are larger than estimated by the U.S. Energy Information Administration. In conclusion, reducing oil dependence therefore remains a valuable goal for U.S. energy policy and an important co-benefit of mitigating greenhouse gas emissions.« less
Xiao, Xiaoyun; Jiang, Qiongchao; Wu, Huan; Guan, Xiaofeng; Qin, Wei; Luo, Baoming
2017-06-01
To compare the diagnostic efficacies of B-mode ultrasound (US), strain elastography (SE), contrast-enhanced ultrasound (CEUS) and the combination of these modalities for breast lesions <1 cm in size. Between January 2013 and October 2015, 203 inpatients with 209 sub-centimetre breast lesions categorised as BI-RADS-US (Breast Imaging Reporting and Data System for Ultrasound) 3-5 were included. US, SE and CEUS were performed to evaluate each lesion. The diagnostic performances of different ultrasonic modalities were compared. The diagnostic efficacies of BI-RADS-US and our re-rating systems were also compared. The pathology findings were used as the reference standard. The specificities of US, SE and CEUS for tumour differentiation were 17.4 %, 56.2 % and 86.0 %, respectively (P < 0.05); and the sensitivities were 100 %, 93.2 % and 93.2 % for US, SE and CEUS, respectively (P < 0.05). The area under the curve (AUC) of the receiver operating characteristic (ROC) curve was 0.867 for original BI-RADS-US, 0.882 for BI-RADS-US combined with only SE, 0.953 for BI-RADS-US combined with only CEUS and 0.924 for BI-RADS-US combined with both SE and CEUS. The best combination was BI-RADS-US combined with only CEUS. Evaluating sub-centimetre breast lesions with SE and CEUS could increase the diagnostic specificity while retaining high sensitivity compared with B-mode ultrasound. • Evaluating breast lesions with SE and CEUS could increase the diagnostic specificity • SE and CEUS offer alternatives to biopsy and possibly allow shorter-interval follow-ups • BI-RADS-US combined with CEUS exhibited the best diagnostic performance.
Lee, Sungwook; Yoon, Juhan; Park, Boyoun; Jun, Youngsoo; Jin, Mirim; Sung, Ha Chin; Kim, Ik-Hwan; Kang, Seongman; Choi, Eui-Ju; Ahn, Byung Yoon; Ahn, Kwangseog
2000-01-01
The human cytomegalovirus US3, an endoplasmic reticulum (ER)-resident transmembrane glycoprotein, forms a complex with major histocompatibility complex (MHC) class I molecules and retains them in the ER, thereby preventing cytolysis by cytotoxic T lymphocytes. To identify which parts of US3 confine the protein to the ER and which parts are responsible for the association with MHC class I molecules, we constructed truncated mutant and chimeric forms in which US3 domains were exchanged with corresponding domains of CD4 and analyzed them for their intracellular localization and the ability to associate with MHC class I molecules. All of the truncated mutant and chimeric proteins containing the luminal domain of US3 were retained in the ER, while replacement of the US3 luminal domain with that of CD4 led to cell surface expression of the chimera. Thus, the luminal domain of US3 was sufficient for ER retention. Immunolocalization of the US3 glycoprotein after nocodazole treatment and the observation that the carbohydrate moiety of the US3 glycoprotein was not modified by Golgi enzymes indicated that the ER localization of US3 involved true retention, without recycling through the Golgi. Unlike the ER retention signal, the ability to associate with MHC class I molecules required the transmembrane domain in addition to the luminal domain of US3. Direct interaction between US3 and MHC class I molecules could be demonstrated after in vitro translation by coimmunoprecipitation. Together, the present data indicate that the properties that allow US3 to be localized in the ER and bind MHC class I molecules are located in different parts of the molecule. PMID:11070025
Bashari, Mohanad; Abbas, Shabbar; Xu, Xueming; Jin, Zhengyu
2014-07-01
In this research work, dextranase was immobilized onto calcium alginate beads by the combination of ultrasonic irradiation and high hydrostatic pressure (US/HHP) treatments. Effects of US/HHP treatments on loading efficiency and immobilization yield of dextranase enzyme onto calcium alginate beads were investigated. Furthermore, the activities of immobilized enzymes prepared with and without US/HHP treatments and that prepared with ultrasonic irradiation (US) and high hydrostatic pressure (HHP), as a function of pH, temperature, recyclability and enzyme kinetic parameters, were compared with that for free enzyme. The maximum loading efficiency and the immobilization yield were observed when the immobilized dextranase was prepared with US (40 W at 25 kHz for 15 min) combined with HHP (400 MPa for 15 min), under which the loading efficiency and the immobilization yield increased by 88.92% and 80.86%, respectively, compared to immobilized enzymes prepared without US/HHP treatment. On the other hand, immobilized enzyme prepared with US/HHP treatment showed Vmax, KM, catalytic and specificity constants values higher than that for the immobilized enzyme prepared with HHP treatment, indicated that, this new US/HHP method improved the catalytic kinetics activity of immobilized dextranase at all the reaction conditions studied. Compared to immobilized enzyme prepared either with US or HHP, the immobilized enzymes prepared with US/HHP method exhibited a higher: pH optimum, optimal reaction temperature, thermal stability and recyclability, and lower activation energy, which, illustrating the effectiveness of the US/HHP method. These results indicated that, the combination of US and HHP treatments could be an effective method for improving the immobilization of enzymes in polymers. Copyright © 2014 Elsevier B.V. All rights reserved.
MO-FG-210-00: US Guided Systems for Brachytherapy
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
Ultrasound (US) is one of the most widely used imaging modalities in medical practice. Since US imaging offers real-time imaging capability, it has becomes an excellent option to provide image guidance for brachytherapy (IGBT). (1) The physics and the fundamental principles of US imaging are presented, and the typical steps required to commission an US system for IGBT is provided for illustration. (2) Application of US for prostate HDR brachytherapy, including partial prostate treatments using MR-ultrasound co-registration to enable a focused treatment on the disease within the prostate is also presented. Prostate HDR with US image guidance planning can benefitmore » from real time visualization of the needles, and fusion of the ultrasound images with T2 weighted MR allows the focusing of the treatment to the specific areas of disease within the prostate, so that the entire gland need not be treated. Finally, (3) ultrasound guidance for an eye plaque program is presented. US can be a key component of placement and QA for episcleral plaque brachytherapy for ocular cancer, and the UCLA eye plaque program with US for image guidance is presented to demonstrate the utility of US verification of plaque placement in improving the methods and QA in episcleral plaque brachytherapy. Learning Objectives: To understand the physics of an US system and the necessary aspects of commissioning US for image guided brachytherapy (IGBT). To understand real time planning of prostate HDR using ultrasound, and its application in partial prostate treatments using MR-ultrasound fusion to focus treatment on disease within the prostate. To understand the methods and QA in applying US for localizing the target and the implant during a episcleral plaque brachytherapy procedures.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chang, Z.
Ultrasound (US) is one of the most widely used imaging modalities in medical practice. Since US imaging offers real-time imaging capability, it has becomes an excellent option to provide image guidance for brachytherapy (IGBT). (1) The physics and the fundamental principles of US imaging are presented, and the typical steps required to commission an US system for IGBT is provided for illustration. (2) Application of US for prostate HDR brachytherapy, including partial prostate treatments using MR-ultrasound co-registration to enable a focused treatment on the disease within the prostate is also presented. Prostate HDR with US image guidance planning can benefitmore » from real time visualization of the needles, and fusion of the ultrasound images with T2 weighted MR allows the focusing of the treatment to the specific areas of disease within the prostate, so that the entire gland need not be treated. Finally, (3) ultrasound guidance for an eye plaque program is presented. US can be a key component of placement and QA for episcleral plaque brachytherapy for ocular cancer, and the UCLA eye plaque program with US for image guidance is presented to demonstrate the utility of US verification of plaque placement in improving the methods and QA in episcleral plaque brachytherapy. Learning Objectives: To understand the physics of an US system and the necessary aspects of commissioning US for image guided brachytherapy (IGBT). To understand real time planning of prostate HDR using ultrasound, and its application in partial prostate treatments using MR-ultrasound fusion to focus treatment on disease within the prostate. To understand the methods and QA in applying US for localizing the target and the implant during a episcleral plaque brachytherapy procedures.« less
Panebianco, Nova; Shofer, Frances; O'Conor, Katie; Wihbey, Tristan; Mulugeta, Lakeisha; Baston, Cameron M; Suzuki, Evan; Alghamdi, Adel; Dean, Anthony
2018-01-30
Emergency department (ED) transvaginal ultrasound (US) is underused in clinical practice. This study assessed pregnant women's perceptions of ED transvaginal US in terms of pain, embarrassment, anxiety, and willingness to receive the procedure. Secondary variables include physicians' perceptions of patients' experiences. Women undergoing US examinations for complications of first-trimester pregnancy were prospectively surveyed before any US and after ED and/or radiology transvaginal US. Patients' and physicians' assessments of pain, embarrassment, and anxiety were measured with visual analog scales (0-100). A total of 398 women were enrolled. In the pre-US survey, the median anxiety score was 14 (interquartile range, 3-51), and 96% of patients were willing to have an ED transvaginal US if necessary. Of those who had ED transvaginal US, 96% would agree to have another examination. Patients reported minimal pain/embarrassment, and there was no difference if performed in the ED versus radiology (median pain, 11.5 versus 13; P = .433; median embarrassment, 7 versus 4; P = .345). Of the 48 who had both ED and radiology transvaginal US, 85% thought the ED transvaginal US was worthwhile. Physicians accurately assessed patient's embarrassment and pain (mean differences, 3.5 and -1.9, respectively; P > .25 for both); however, they overestimated them relative to the pelvic examination (mean difference for embarrassment, 12.8; P < .0001; pain, 8.0; P = .01). Pregnant ED patients report low levels of anxiety, pain, and embarrassment, and after ED transvaginal US, 96% would agree to have the examination again. There is no difference in pain/embarrassment between ED and radiology transvaginal US. Emergency department physicians accurately assessed patients' pain and embarrassment with ED transvaginal US but overestimated them compared to the pelvic examination. © 2018 by the American Institute of Ultrasound in Medicine.
... Card Other Resources ChooseMyPlate.gov (U.S. Department of Agriculture, U.S. Department of Health and Human Services) DASH ( ... Dietary Guidelines for Americans, 2010 (U.S. Department of Agriculture, U.S. Department of Health and Human Services) High ...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yokosawa, A.
The author described the polarized-proton and polarized-antiproton beams up to 200 GeV/c at Fermilab. The beam line, called MP, consists of the 400-m long primary and 350-m long secondary beam line followed by 60-m long experimental hall. We discuss the characteristics of the polarized beams. The Fermilab polarization projects are designated at E-581/704 initiated and carried out by an international collaboration, Argonne (US), Fermilab (US), Kyoto-Kyushu-Hiroshima-KEK (Japan), LAPP (France), Northwestern University (US), Los Alamos Laboratory (US), Rice (US), Saclay (France), Serpukhov (USSR), INFN Trieste (Italy), and University of Texas (US).
2009-07-24
Africa Domestic Exports, FAS value; Imports for Consumption , Customs Value; Actual U.S. dollars Trade Flow 2007 2008 Jan. – May 2008 Jan. –May 2009 U.S...first part of 2009. However, decreases in U.S. and global consumption are likely to continue to have a negative effect on most exports from the region.39...Table 3. Leading U.S. Imports from Sub-Saharan Africa U.S. Imports for Consumption , Customs Value, Actual U.S. dollars HTS Description 2007 2008
Garay, Osvaldo Ulises; Elorrio, Ezequiel Garcia; Rodríguez, Viviana; Spira, Cintia; Augustovski, Federico; Pichon-Riviere, Andrés
2017-12-01
Re-use of medical devices labeled and marketed for single use only is a current practice around the world. To estimate the average difference per surgery in device-related costs (DRCs) when performed with single-use devices under a single-use policy (SUP) instead of a re-use policy (RP) from the perspective of the private health sector of Argentina. An analytical model was developed in Microsoft Excel and populated with data from a literature review, a Delphi-like panel, and local cost estimations. Four single-use devices were selected for analysis: plastic trocars, endocutters, linear cutters, and harmonic scalpels. DRCs were expressed in 2012 US dollars and divided into four cost categories: devices, adverse events, device failure, and surgical time extension. Outputs were expressed as DRCs per surgery under a SUP, under a RP, the difference between them expressed in US dollars (Diff_$), and the difference between them expressed as a percentage of surgery costs (Diff_%S). Deterministic and probabilistic sensitivity analyses were performed to analyze the impact of uncertainty on results. Expected DRCs per surgery were as follows: for trocars: SUP, US $424.6; RP, US $244.2; Diff_$, US $-180.4; and Diff_%S, -3.8%; for endocutters: SUP, US $1667.4; RP, US $1102.3; Diff_$, US $-565.1; and Diff_%S, -11.1%; for linear cutters: SUP, US $1228.1; RP, US $1045.9; Diff_$, US $-182.2; and Diff_%S, -3.4%; and for harmonic scalpels: SUP, US $1040.9; RP, US $292.4; Diff_$, US $-748.5; and Diff_%S, -14.8%. Sensitivity analyses showed results to be robust. RP was shown to be less costly in all devices and scenarios considered. Nevertheless, the real frequency of adverse events and their cost implications are still uncertain. More research is needed to assess the effectiveness and safety of these off-label policies. Copyright © 2017. Published by Elsevier Inc.
Kim, Seung Hyup
2008-01-01
Objective To evaluate the correlations between prostate volumes estimated by transabdominal, transrectal, and three-dimensional US and the factors affecting the differences. Materials and Methods The prostate volumes of 94 consecutive patients were measured by both transabdominal and transrectal US. Next, the prostate volumes of 58 other patients was measured by both transrectal and three-dimensional US. We evaluated the degree of correlation and mean difference in each comparison. We also analyzed possible factors affecting the differences, such as the experiences of examiners in transrectal US, bladder volume, and prostate volume. Results In the comparison of transabdominal and transrectal US methods, the mean difference was 8.4 ± 10.5 mL and correlation coefficient (r) was 0.775 (p < 0.01). The experienced examiner for the transrectal US method had the highest correlation (r = 0.967) and the significantly smallest difference (5.4 ± 3.9 mL) compared to the other examiners (the beginner and the trained; p < 0.05). Prostate volume measured by transrectal US showed a weak correlation with the difference (r = 0.360, p < 0.05). Bladder volume did not show significant correlation with the difference (r = -0.043, p > 0.05). The comparison between the transrectal and three-dimensional US methods revealed a mean difference of 3.7 ± 3.4 mL and the correlation coefficient was 0.924 for the experienced examiner. Furthermore, no significant difference existed between examiners (p > 0.05). Prostate volume measured by transrectal US showed a positive correlation with the difference for the beginner only (r = 0.405, p < 0.05). Conclusion In the prostate volume estimation by US, experience in transrectal US is important in the correlation with transabdominal US, but not with three-dimensional US. Also, less experienced examiners' assessment of the prostate volume can be affected by prostate volume itself. PMID:18385560
Choi, J S; Choi, Y- J; Kim, E K; Yoon, J H; Youk, J H; Han, K H; Moon, H J; Kang, W J; Kwak, J Y
2014-02-01
To assess the risk of malignancy of thyroid incidentalomas found on 18F-FDG PET/CT by US features and cytologic results, and to evaluate the clinical usage of a combination of US features and cytology for post-FNA management of thyroid incidentalomas on 18F-FDG PET/CT. From September 2006 to December 2008, 132 patients with 134 thyroid incidentalomas detected on 18F-FDG PET/CT who had undergone US and US-FNA were included in this study. We evaluated the malignancy rate of thyroid incidentalomas in different subgroups subdivided by US features and US-FNA cytology results. Several variables were compared between the benign and malignant group. The risk of malignancy was 58.2 % (78/132) in thyroid incidentalomas on 18F-FDG PET/CT. Age, gender, and tumor size were not significantly different between the malignant and benign group. Malignancy rate of thyroid incidentalomas was significantly higher in the suspicious malignant (88.9 %) than in the probably benign group (11.3 %) on US (p < 0.001). Malignancy rates were high in thyroid nodules with "malignancy", "suspicious for malignancy", or "follicular neoplasm" on cytologic results, regardless of US features. However, malignancy rates of thyroid incidentalomas with "unsatisfactory" or "benign" results on cytology were higher in the suspicious malignant (75 %, 12.5 %, respectively) than in the probably benign (0 %) group on US. This study demonstrated that the risk of malignancy was high in thyroid incidentalomas on 18F-FDG PET/CT even without suspicious US features. However, there was no malignancy in nodules with no suspicious US features and benign cytology. Based on these results, we concluded that US may not replace FNA in the diagnosis of PET incidentalomas, and that a follow-up may be considered of thyroid incidentalomas with benign cytology and no suspicious US features. © Georg Thieme Verlag KG Stuttgart · New York.
Fan, Xiaozhou; Wang, Luofu; Guo, Yanli; Xiong, Xingyu; Zhu, Lianhua; Fang, Kejing
2016-01-01
Ultrasound (US)-targeted microbubble destruction has been widely used as an effective drug-delivery system. However, nanobubbles (NBs) have better stability and stronger penetration than microbubbles, and drug delivery assisted by US-targeted NB destruction (UTND) still needs to be investigated. Our aim was to investigate the effect of doxorubicin (DOX) on the inhibition of prostate cancer growth under UTND. Contrast-enhanced US imaging of transplanted PC3 prostate cancer in mice showed that under a combination of 1 W/cm2 US power and a 100 Hz intermittent pulse with a “5 seconds on, 5 seconds off” mode, NBs with an average size of (485.7±33) nm were effectively destroyed within 15 minutes in the tumor location. PC3 cells and 20 tumor-bearing mice were divided into four groups: a DOX group, a DOX + NB group, a DOX + US group, and a DOX + NB + US group. The cell growth-inhibition rate and DOX concentration of xenografts in the DOX + NB + US group were highest. Based on another control group and these four groups, another 25 tumor-bearing mice were used to observe the treatment effect of nine DOX injections under UTND. The xenografts in the DOX + NB + US group decreased more obviously and had more cellular apoptosis than other groups. Finally, electron microscopy was used to estimate the cavitation effect of NBs under US irradiation in the control group, NB group, US group, and NB + US group. The results of scanning electron microscopy showed that PC3 cells in the DOX + NB + US group had more holes and significantly increased cell-surface folds. Meanwhile, transmission electric microscopy confirmed that more lanthanum nitrate particles entered the parenchymal cells in xenografts in the NB + US group compared with the other groups. This study suggested that UTND technology could be an effective method to promote drugs to function in US-irradiated sites, and the underlying mechanism may be associated with a cavitation effect. PMID:27536100
Investment, population growth and GNP as determinants of US immigration.
Kritz, M M
1998-09-01
Northern countries typically attract migrants from poorer countries because of the formers' high wage rates and demand for labor. In particular, the US receives large numbers of legal migrants from almost every country and region of the world. This paper explores the determinants of permanent emigration to the US during 1989-93 using data drawn from the US Immigration and Naturalization Service (INS) Annual Tapes for the period. The analysis is restricted to only legal migration from 150 countries, and specifically investigates whether emigration to the US during 1989-93 can be accounted for by demographic and economic conditions in sending countries, or by levels of US investment in sending countries. No support is found for claims that rapid population growth and US investment fuel US immigration; emigration is comparatively far lower from countries experiencing rapid population growth and not significantly correlated with US investment, while the US typically invests the most in the more developed countries which send relatively few migrants to the US. Geographic proximity is the most important correlate of migration, followed by the population size of sending countries, which is negatively related to emigration. Some evidence was found that emigration will decrease as countries develop. Who a country decides to admit and how many people are admitted depend mainly upon public policy and very little upon the economic and demographic conditions of sending countries.
Impact of medical travel on imports and exports of medical services.
Johnson, Tricia J; Garman, Andrew N
2010-12-01
Medical travel is travel outside of an individual's home region or country in pursuit of medical care that is more accessible, of higher quality and/or of lower cost. This paper estimates the inflows of foreign residents seeking medical care in the U.S. and outflows of U.S. residents seeking care abroad. Using data from the U.S. Bureau of Economic Analysis, U.S. International Trade Administration and a survey of domestic health care providers, we estimate the lower and upper bounds for the number of medical travelers into and out of the U.S. and the value of these services. We estimate that between 43,000 and 103,000 foreigners came into the U.S. for medical care, and between 50,000 and 121,000 U.S. residents traveled abroad for care in 2007. Despite a net loss in the number of medical travelers flowing out of the U.S. for care, the trade surplus for medical travel could be as high as $1 billion. While a slight net outflow of patients leaving the U.S. for medical care may exist, the resulting impact on exports is still positive for the U.S., due to a higher average spending per patient coming to the U.S. New mechanisms are needed to track the balance of mobility and trade for medical care on a regular basis. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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View the 1997 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 1995.
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Ultrasound Produces Extensive Brain Activation via a Cochlear Pathway.
Guo, Hongsun; Hamilton, Mark; Offutt, Sarah J; Gloeckner, Cory D; Li, Tianqi; Kim, Yohan; Legon, Wynn; Alford, Jamu K; Lim, Hubert H
2018-06-06
Ultrasound (US) can noninvasively activate intact brain circuits, making it a promising neuromodulation technique. However, little is known about the underlying mechanism. Here, we apply transcranial US and perform brain mapping studies in guinea pigs using extracellular electrophysiology. We find that US elicits extensive activation across cortical and subcortical brain regions. However, transection of the auditory nerves or removal of cochlear fluids eliminates the US-induced activity, revealing an indirect auditory mechanism for US neural activation. Our findings indicate that US activates the ascending auditory system through a cochlear pathway, which can activate other non-auditory regions through cross-modal projections. This cochlear pathway mechanism challenges the idea that US can directly activate neurons in the intact brain, suggesting that future US stimulation studies will need to control for this effect to reach reliable conclusions. Copyright © 2018 Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Cohen, Timmerie; Justice, M. Ferell; Dempsey, Melanie C.
2014-01-01
This research compared three clinical preparedness domains, communication ability, social comfort, and clinical confidence, between US-born and non-US born radiation sciences students. The aim of the study was to determine if there were perceived differences in clinical preparedness between them. Student's place of birth was found to be an…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-06
...] Rollins College; T.A. Loving Co.; US Ecology Idaho, Inc.; and West Pharmaceutical Services, Inc... 11481 1910.37(i). T.A. Loving Co V-74-43 04/13/1976 41 FR 15483 1918.66(f)(1)(i). US Ecology Idaho, Inc.... US Ecology Idaho, Inc. The Agency granted Envirosafe Services, Inc. (now US Ecology Idaho, Inc.), a...
Eastern U.S. Infrared, Enhancement 4 - NOAA GOES Geostationary Satellite
Enhancement 4 Eastern U.S. Infrared Enhancements IR Enhancement 1 Eastern U.S. Infrared Enhancement 1 IR Enhancement 2 Eastern U.S. Infrared Enhancement 2 IR Enhancement 3 Eastern U.S. Infrared Enhancement 3 IR large amount of water vapor. » Enhancement types In an infrared (IR) image cold clouds are high clouds
ERIC Educational Resources Information Center
Office of Elementary and Secondary Education (ED), Washington, DC. Migrant Education Programs.
This directory promotes better coordination among agencies and organizations that serve migrant and seasonal farmworkers (MSFWs) and their families. The U.S. Department of Agriculture, the U.S. Department of Education, the U.S. Environmental Protection Agency, the U.S. Department of Health and Human Services, the U.S. Department of Justice, and…
Preparing for Post-Embargo Cuba: Effects on Businesses and Consumers.
ERIC Educational Resources Information Center
Ray, Nina M.; And Others
1995-01-01
Discusses a brief history of U.S. trade with Cuba, the current status of Cuba's role in world trade, and the effects the U.S. embargo has on American businesses and U.S. and Cuban citizens. The article presents suggestions on how U.S. businesses can prepare for an open Cuba and argues for the lifting of the U.S. embargo against Cuba. (84…
17 CFR Appendix A to Part 151 - Spot-Month Position Limits
Code of Federal Regulations, 2013 CFR
2013-04-01
... Referencedcontract spot- month limit Agricultural Referenced Contracts ICE Futures U.S. Cocoa 1,000 ICE Futures U.S. Coffee C 500 Chicago Board of Trade Corn 600 ICE Futures U.S. Cotton No. 2 300 ICE Futures U.S. FCOJ-A... of Trade Soybean Meal 720 Chicago Board of Trade Soybean Oil 540 ICE Futures U.S. Sugar No. 11 5,000...
17 CFR Appendix A to Part 151 - Spot-Month Position Limits
Code of Federal Regulations, 2012 CFR
2012-04-01
... Referencedcontract spot- month limit Agricultural Referenced Contracts ICE Futures U.S. Cocoa 1,000 ICE Futures U.S. Coffee C 500 Chicago Board of Trade Corn 600 ICE Futures U.S. Cotton No. 2 300 ICE Futures U.S. FCOJ-A... of Trade Soybean Meal 720 Chicago Board of Trade Soybean Oil 540 ICE Futures U.S. Sugar No. 11 5,000...
A Case Study on the Development and Implementation of Cyber Capabilities in the United States
ERIC Educational Resources Information Center
Walton, Marquetta
2016-01-01
The effectiveness of U.S. cyber-capabilities can have a serious effect on the cyber-security stance of the US and significantly impact how well U.S. critical infrastructures are protected. The problem is that the state of the U.S. cyber-security could be negatively impacted by the dependency that the US displays in its use of defensive…
ERIC Educational Resources Information Center
Chisholm, Alex
2014-01-01
This Data-to-Go brief summarizes five year GMAT testing trends for US and Canadian residents, and race/ethnicity breakdowns for US citizens. It includes: (1) GMAT exams taken by US region, US state of residence, and race/ethnicity of examinees (US citizens only), (2) GMAT exams taken by Canadian residents, by Canadian province, (3) GMAT exams…
Cost-Effectiveness of Early Versus Standard Antiretroviral Therapy in HIV-Infected Adults in Haiti
Koenig, Serena P.; Bang, Heejung; Severe, Patrice; Jean Juste, Marc Antoine; Ambroise, Alex; Edwards, Alison; Hippolyte, Jessica; Fitzgerald, Daniel W.; McGreevy, Jolion; Riviere, Cynthia; Marcelin, Serge; Secours, Rode; Johnson, Warren D.; Pape, Jean W.; Schackman, Bruce R.
2011-01-01
Background In a randomized clinical trial of early versus standard antiretroviral therapy (ART) in HIV-infected adults with a CD4 cell count between 200 and 350 cells/mm3 in Haiti, early ART decreased mortality by 75%. We assessed the cost-effectiveness of early versus standard ART in this trial. Methods and Findings Trial data included use of ART and other medications, laboratory tests, outpatient visits, radiographic studies, procedures, and hospital services. Medication, laboratory, radiograph, labor, and overhead costs were from the study clinic, and hospital and procedure costs were from local providers. We evaluated cost per year of life saved (YLS), including patient and caregiver costs, with a median of 21 months and maximum of 36 months of follow-up, and with costs and life expectancy discounted at 3% per annum. Between 2005 and 2008, 816 participants were enrolled and followed for a median of 21 months. Mean total costs per patient during the trial were US$1,381 for early ART and US$1,033 for standard ART. After excluding research-related laboratory tests without clinical benefit, costs were US$1,158 (early ART) and US$979 (standard ART). Early ART patients had higher mean costs for ART (US$398 versus US$81) but lower costs for non-ART medications, CD4 cell counts, clinically indicated tests, and radiographs (US$275 versus US$384). The cost-effectiveness ratio after a maximum of 3 years for early versus standard ART was US$3,975/YLS (95% CI US$2,129/YLS–US$9,979/YLS) including research-related tests, and US$2,050/YLS excluding research-related tests (95% CI US$722/YLS–US$5,537/YLS). Conclusions Initiating ART in HIV-infected adults with a CD4 cell count between 200 and 350 cells/mm3 in Haiti, consistent with World Health Organization advice, was cost-effective (US$/YLS <3 times gross domestic product per capita) after a maximum of 3 years, after excluding research-related laboratory tests. Trial registration ClinicalTrials.gov NCT00120510 Please see later in the article for the Editors' Summary PMID:21949643
Vaduganathan, Muthiah; Harrington, Robert A.; Stone, Gregg W.; Steg, Ph. Gabriel; Gibson, C. Michael; Hamm, Christian W.; Price, Matthew J.; Prats, Jayne; Deliargyris, Efthymios N.; Mahaffey, Kenneth W.; White, Harvey D.
2016-01-01
Background— The Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition (CHAMPION) PHOENIX trial demonstrated superiority of cangrelor in reducing ischemic events at 48 hours in patients undergoing percutaneous coronary intervention compared with clopidogrel. Methods and Results— We analyzed all patients included in the modified intention-to-treat analysis in US (n=4097; 37.4%) and non-US subgroups (n=6845; 62.6%). The US cohort was older, had a higher burden of cardiovascular risk factors, and had more frequently undergone prior cardiovascular procedures. US patients more frequently underwent percutaneous coronary intervention for stable angina (77.9% versus 46.2%). Almost all US patients (99.1%) received clopidogrel loading doses of 600 mg, whereas 40.5% of non-US patients received 300 mg. Bivalirudin was more frequently used in US patients (56.7% versus 2.9%). At 48 hours, rates of the primary composite end point were comparable in the US and non-US cohorts (5.5% versus 5.2%; P=0.53). Cangrelor reduced rates of the primary composite end point compared with clopidogrel in US (4.5% versus 6.4%; odds ratio 0.70 [95% confidence interval 0.53–0.92]) and in non-US patients (4.8% versus 5.6%; odds ratio 0.85 [95% confidence interval 0.69–1.05]; interaction P=0.26). Similarly, rates of the key secondary end point, stent thrombosis, were reduced by cangrelor in both regions. Rates of Global Use of Strategies to Open Occluded Arteries (GUSTO)–defined severe bleeding were low and not significantly increased by cangrelor in either region. Conclusions— Despite broad differences in clinical profiles and indications for percutaneous coronary intervention by region in a large global cardiovascular clinical trial, cangrelor consistently reduced rates of ischemic end points compared with clopidogrel without an excess in severe bleeding in both the US and non-US subgroups. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01156571. PMID:27313282
Role of specimen US for predicting resection margin status in breast conserving therapy
MOSCHETTA, M.; TELEGRAFO, M.; INTRONA, T.; COI, L.; RELLA, L.; RANIERI, V.; CIRILLI, A.; IANORA, A.A. STABILE; ANGELELLI, G.
2015-01-01
Aim To assess the diagnostic accuracy of specimen ultrasound (US) for predicting resection margin status in women undergoing breast conserving therapy for US-detected cancer, having the histological findings as the reference standard. Patients and methods A total of 132 consecutive patients (age range, 34–87 years; mean, 51 years) underwent breast-conserving surgery for US-detected invasive breast cancer. All surgical specimens underwent US examination. The presence of lesion within the specimen and its distance from the specimen margins were assessed considering a threshold distance between the lesion and specimen margins of 10 mm. US findings were then compared with the pathological ones and specimen US. Sensitivity, specificity, diagnostic accuracy, positive (PPV) and negative predictive values (NPV) for predicting histological margin status were evaluated, having the histological findings as the reference standard. Results The histological examination detected invasive ductal carcinoma in 96/132 (73%) cases, invasive lobular carcinoma in 32/132 (24%), mucinous carcinoma in 4/132 (3%). The pathological margin analysis revealed 96/132 (73%) negative margins and 36 (27%) close/positive margins. US examination detected all 132 breast lesions within the surgical specimens. 110 (83%) negative margins and 22 (17%) positive margins were found on US. Sensitivity, specificity, diagnostic accuracy, PPV and NPV of 44%, 94%, 80%, 73% and 82%, respectively, were found for specimen US. Conclusions Specimen US represents a time and cost saving imaging tool for evaluating the presence of US detected-breast lesion within surgical specimen and for predicting the histological margin status. PMID:26712255
Bree, R L; Arnold, R J; Pettit, K G; Kaniecki, D J; O'haeri, C; LaFrance, N D; Toaff, A L
2001-03-01
The authors performed this study to compare the cost and diagnostic abilities of ultrasound (US) performed with and without the use of an oral contrast material recently approved by the U.S. Food and Drug Administration. An interactive decision-analytic model was constructed to compare US performed with and without contrast material (SonoRx; Bracco Diagnostics) for the evaluation of patients with abdominal pain who were suspected of having pancreatic disease. The model considered all resources that might be used to evaluate a patient suspected of having pancreatic disease (eg, US, computed tomography [CT], endoscopic retrograde cholangiopancreatography, fine-needle aspiration biopsy, and open biopsy). The literature and an expert panel were the clinical data sources. Cost estimates were based on Medicare and non-Medicare reimbursements. The primary cost-effectiveness measure was the cost to achieve a diagnosis. SonoRx-enhanced US was less expensive than unenhanced US ($714 vs $808, respectively, with Medicare costs; $1,612 vs $1,878, respectively, with non-Medicare costs) and as effective (0.785 vs 0.782, respectively). SonoRx-enhanced US was more cost-effective than unenhanced US ($909 vs $1,034, respectively, with Medicare costs; $2,052 vs $2,401, respectively, with non-Medicare costs). This relationship was maintained throughout extensive sensitivity analyses. SonoRx-enhanced US is more cost-effective than unenhanced US, primarily because it avoids the need for CT. CT may be avoided owing to the higher probability of obtaining optimal US scans with oral contrast material.
NREL: U.S. Life Cycle Inventory Database - Publications
Publications Planning Documents U.S. Life Cycle Inventory Database Roadmap, February 2009 U.S. Life Cycle Inventory User Survey, February 2009 U.S. LCI Database Factsheet, March 2005 User's Guide for Life
Food Safety for People with HIV/AIDS
... been diagnosed with HIV/AIDS U.S. Department of Agriculture Food Safety and Inspection Service U.S. Department of ... for you. That’s why the U.S. Department of Agriculture’s Food Safety and Inspection Service and the U.S. ...
Operating and Support Costing Guide: Army Weapon Systems
1974-12-23
First US Army 1 Commandant, US Army Logistics Management Center (Director Administration and Services) 2 Commander, US Army Management Systems Support...Army Logistics Management Center (Director, Administration and Services) Commander, US Army Management Systems Support Agency (DACS-AME) Commander
The economic costs of malaria in children in three sub-Saharan countries: Ghana, Tanzania and Kenya
2013-01-01
Background Malaria causes significant mortality and morbidity in sub-Saharan Africa (SSA), especially among children less than five years of age (U5 children). Although the economic burden of malaria in this region has been assessed previously, the extent and variation of this burden remains unclear. This study aimed to estimate the economic costs of malaria in U5 children in three countries (Ghana, Tanzania and Kenya). Methods Health system and household costs previously estimated were integrated with costs associated with co-morbidities, complications and productivity losses due to death. Several models were developed to estimate the expected treatment cost per episode per child, across different age groups, by level of severity and with or without controlling for treatment-seeking behaviour. Total annual costs (2009) were calculated by multiplying the treatment cost per episode according to severity by the number of episodes. Annual health system prevention costs were added to this estimate. Results Household and health system costs per malaria episode ranged from approximately US$ 5 for non-complicated malaria in Tanzania to US$ 288 for cerebral malaria with neurological sequelae in Kenya. On average, up to 55% of these costs in Ghana and Tanzania and 70% in Kenya were assumed by the household, and of these costs 46% in Ghana and 85% in Tanzania and Kenya were indirect costs. Expected values of potential future earnings (in thousands) lost due to premature death of children aged 0–1 and 1–4 years were US$ 11.8 and US$ 13.8 in Ghana, US$ 6.9 and US$ 8.1 in Tanzania, and US$ 7.6 and US$ 8.9 in Kenya, respectively. The expected treatment costs per episode per child ranged from a minimum of US$ 1.29 for children aged 2–11 months in Tanzania to a maximum of US$ 22.9 for children aged 0–24 months in Kenya. The total annual costs (in millions) were estimated at US$ 37.8, US$ 131.9 and US$ 109.0 nationwide in Ghana, Tanzania and Kenya and included average treatment costs per case of US$ 11.99, US$ 6.79 and US$ 20.54, respectively. Conclusion This study provides important insight into the economic burden of malaria in SSA that may assist policy makers when designing future malaria control interventions. PMID:24004482
"Top Performing" US Hospitals and the Health Status of Counties they Serve.
Maraccini, Amber M; Yang, Wei; Slonim, Anthony D
2018-06-01
This study (a) examined the relationships between "top performing" US hospitals and the health status of counties they serve and (b) compared the health status of "top performing" US hospital counties versus that of remaining US counties. Statistical analyses considered US News and World Report Honor Roll ranking data, as a measure of hospital performance, and County Health Rankings (CHR) data, as a measure of county health status. "Top performing" hospital Honor Roll scores were correlated with measures of Clinical Care (p < 0.001). Counties with "top performing" US hospitals presented greater health status with regard to All Health Outcomes (p < 0.001), Length of Life (p < 0.001), Quality of Life (p < 0.001), All Health Factors (p < 0.001), Health Behaviors (p < 0.001), and Clinical Care (p < 0.001), than compared to remaining US counties. Hospital impact on county health status remains primarily recognized in clinical care and not in overall health. Also, counties that contain a "top performing" US hospital tend to present lower health risks to their citizens than compared to other US counties.
Minami, Yasunori; Kudo, Masatoshi
2009-12-31
The success rate of percutaneous radiofrequency (RF) ablation for hepatocellular carcinoma (HCC) depends on correct targeting via an imaging technique. However, RF electrode insertion is not completely accurate for residual HCC nodules because B-mode ultrasound (US), color Doppler, and power Doppler US findings cannot adequately differentiate between treated and viable residual tumor tissue. Electrode insertion is also difficult when we must identify the true HCC nodule among many large regenerated nodules in cirrhotic liver. Two breakthroughs in the field of US technology, harmonic imaging and the development of second-generation contrast agents, have recently been described and have demonstrated the potential to dramatically broaden the scope of US diagnosis of hepatic lesions. Contrast-enhanced harmonic US imaging with an intravenous contrast agent can evaluate small hypervascular HCC even when B-mode US cannot adequately characterize tumor. Therefore, contrast-enhanced harmonic US can facilitate RF ablation electrode placement in hypervascular HCC, which is poorly depicted by B-mode US. The use of contrast-enhanced harmonic US in ablation therapy for liver cancer is an efficient approach.
Srinivasan, Abhay; Servaes, Sabah; Peña, Andrès; Darge, Kassa
2015-02-01
To improve diagnosis of pediatric appendicitis, many institutions have implemented a staged imaging protocol utilizing ultrasonography (US) first and then computed tomography (CT). A substantial number of children with suspected appendicitis undergo CT after US, and the efficient and accurate diagnosis of pediatric appendicitis continues to be challenging. The objective of the study is to characterize the utility of CT following US for diagnosis of pediatric appendicitis, in conjunction with a clinical appendicitis score (AS). Imaging studies of children with suspected appendicitis who underwent CT after US in an imaging protocol were retrospectively reviewed by three radiologists in consensus. Chart review derived the AS (range 0-10) and obtained the patient diagnosis and disposition, and an AS was applied to each patient. Clinical and radiologic data were analyzed to assess the yield of CT after US. Studies of 211 children (mean age 11.3 years) were included. The positive threshold for AS was determined to be 6 out of 10. When AS and US were concordant (N = 140), the sensitivity and specificity of US were similar to CT. When AS and US were discordant (N = 71) and also when AS ≥ 6 (N = 84), subsequent CT showed superior sensitivity and specificity to US alone. In the subset where US showed neither the appendix nor inflammatory change in the right lower quadrant (126/211, 60 % of scans), when AS < 6 (N = 83), the negative predictive value (NPV) of US was 0.98. However, when AS ≥ 6 (N = 43), NPV of US was 0.58, and the positive predictive value of subsequent CT was 1. There was a significant decrease in depiction of the appendix on US with patient weight-to-age ratio of >6 (kg/year, P < 0.001) and after-hours (1700 -0730 hours) performance of US (P < 0.001). Results suggest that the appendicitis score has utility in guiding an imaging protocol and support the contention that non-visualization of the appendix on US is not intrinsically non-diagnostic. There was little benefit to additional CT when AS < 6 and US did not show the appendix or evidence of inflammation; this would have avoided CT in 140/211 (66 %) patients. CT demonstrated benefit when AS ≥ 6, suggesting that cases with AS ≥ 6 and features that limit depiction of the appendix on US may be triaged to CT.
U.S. Northern Command > Newsroom > Fact Sheets
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Code of Federal Regulations, 2010 CFR
2010-04-01
... would have qualified under the U.S. system based on the minimum PIA. (The minimum benefit will be based... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Supplementing the U.S. benefit if the total amount of the combined benefits is less than the U.S. minimum benefit. 404.1920 Section 404.1920...
21 CFR 177.1820 - Styrene-maleic anhydride copolymers.
Code of Federal Regulations, 2013 CFR
2013-04-01
... will pass through a U.S. standard sieve No. 10 and will be held on a U.S. standard sieve No. 20 0.02... sieve No. 10 and will be held on a U.S. standard sieve No. 20. 2. Styrene-maleic anhydride copolymer... particles of a size that will pass through a U.S. standard sieve No. 10 and will be held on a U.S. standard...
21 CFR 177.1820 - Styrene-maleic anhydride copolymers.
Code of Federal Regulations, 2012 CFR
2012-04-01
... will pass through a U.S. standard sieve No. 10 and will be held on a U.S. standard sieve No. 20 0.02... sieve No. 10 and will be held on a U.S. standard sieve No. 20. 2. Styrene-maleic anhydride copolymer... particles of a size that will pass through a U.S. standard sieve No. 10 and will be held on a U.S. standard...
Iran: U.S. Concerns and Policy Responses
2007-10-09
by U.S. sanctions). Exports to U.S. — $157 million (large categories: pomegranate juice, caviar, pistachio nuts, carpets, medicines, artwork...Iranian carpets before the 1979 revolution, but U.S. anti-dumping tariffs imposed on Iranian pistachio nut imports in 1986 (over 300%) dampened imports...of that product. In January 2003, the tariff on roasted pistachios was lowered to 22% and on raw pistachios to 163%. In December 2004, U.S
Apparatus and Methods Using Highly Optically Dispersive Media
2011-08-02
University ; Sep. 24, 2001. * cited by examiner Primary Examiner- Michael A Lyons (74) Attorney , Agent, or Firm- William J. Greener; Bond...NY (US); Daniel J. Gauthier, Durham, NC (US); Zhimin Shi, Rochester, NY (US) (73) Assignees: University of Rochester, Rochester, NY (US); Duke... University , Durham, NC (US) ( *) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 250
ERIC Educational Resources Information Center
Rahman, Mai Abdul; Turner, J. Fidel; Elbedour, Salman
2015-01-01
Background: The drastic surge in the number of homeless families in the United States (U.S.) has resulted in an increase in the number of homeless students attending U.S. public schools. Meanwhile, the U.S. public school system is struggling to meet the educational needs of their homeless students. Objective: This study examined the historical…
U.S. Space Policy and Space Industry Strangulation
2010-03-01
protecting U.S. national security, and creating an environment in which non-U.S. citizens can participate fully in the U.S. space industry. 14...still protecting U.S. national security, and creating an environment in which non-U.S. citizens can participate fully in the U.S. space industry...security, and creating and sustaining a globally competitive space industry. These realms are not mutually exclusive. If technologies are overly guarded
Modeling future U.S. forest sector market and trade impacts of expansion in wood energy consumption
Peter J. Ince; Andrew D. Kramp; Kenneth E. Skog; Do-il Yoo; V. Alaric Sample
2011-01-01
This paper describes an approach to modeling U.S. forest sector market and trade impacts of expansion in domestic wood energy consumption under hypothetical future U.S. wood biomass energy policy scenarios. The U.S. Forest Products Module (USFPM) was created to enhance the modeling of the U.S. forest sector within the Global Forest Products Model (GFPM), providing a...
US Topo—Topographic maps for the Nation
Fishburn, Kristin A.; Carswell, William J.
2017-06-23
Building on the success of 125 years of mapping, the U.S. Geological Survey created US Topo, a georeferenced digital map produced from The National Map data. US Topo maps are designed to be used like the traditional 7.5-minute quadrangle paper topographic maps for which the U.S. Geological Survey is so well known. However, in contrast to paper-based maps, US Topo maps provide modern technological advantages that support faster, wider public distribution and basic, onscreen geospatial analysis, including the georeferencing capability to display the ground coordinate location as the user moves the cursor around the map.
Total economic value of wetlands products and services in Uganda.
Kakuru, Willy; Turyahabwe, Nelson; Mugisha, Johnny
2013-01-01
Wetlands provide food and non-food products that contribute to income and food security in Uganda. This study determined the economic value of wetland resources and their contribution to food security in the three agroecological zones of Uganda. The values of wetland resources were estimated using primary and secondary data. Market price, Productivity, and Contingent valuation methods were used to estimate the value of wetland resources. The per capita value of fish was approximately US$ 0.49 person⁻¹. Fish spawning was valued at approximately US$ 363,815 year⁻¹, livestock pastures at US$ 4.24 million, domestic water use at US$ 34 million year⁻¹, and the gross annual value added by wetlands to milk production at US$ 1.22 million. Flood control was valued at approximately US$ 1,702,934,880 hectare⁻¹ year⁻¹ and water regulation and recharge at US$ 7,056,360 hectare⁻¹ year⁻¹. Through provision of grass for mulching, wetlands were estimated to contribute to US$ 8.65 million annually. The annual contribution of non-use values was estimated in the range of US$ 7.1 million for water recharge and regulation and to US$ 1.7 billion for flood control. Thus, resource investment for wetlands conservation is economically justified to create incentives for continued benefits.
Total Economic Value of Wetlands Products and Services in Uganda
Kakuru, Willy; Turyahabwe, Nelson; Mugisha, Johnny
2013-01-01
Wetlands provide food and non-food products that contribute to income and food security in Uganda. This study determined the economic value of wetland resources and their contribution to food security in the three agroecological zones of Uganda. The values of wetland resources were estimated using primary and secondary data. Market price, Productivity, and Contingent valuation methods were used to estimate the value of wetland resources. The per capita value of fish was approximately US$ 0.49 person−1. Fish spawning was valued at approximately US$ 363,815 year−1, livestock pastures at US$ 4.24 million, domestic water use at US$ 34 million year−1, and the gross annual value added by wetlands to milk production at US$ 1.22 million. Flood control was valued at approximately US$ 1,702,934,880 hectare−1 year−1 and water regulation and recharge at US$ 7,056,360 hectare−1 year−1. Through provision of grass for mulching, wetlands were estimated to contribute to US$ 8.65 million annually. The annual contribution of non-use values was estimated in the range of US$ 7.1 million for water recharge and regulation and to US$ 1.7 billion for flood control. Thus, resource investment for wetlands conservation is economically justified to create incentives for continued benefits. PMID:24163614
Differences in the self-reported racism experiences of US-born and foreign-born Black pregnant women
Dominguez, Tyan Parker; Strong, Emily Ficklin; Krieger, Nancy; Gillman, Matthew W.; Rich-Edwards, Janet W.
2013-01-01
Differential exposure to minority status stressors may help explain differences in United States (US)-born and foreign-born Black women’s birth outcomes. We explored self-reports of racism recorded in a survey of 185 US-born and 114 foreign-born Black pregnant women enrolled in Project Viva, a prospective cohort study of pregnant women in Boston, Massachusetts, USA. Self-reported prevalence of personal racism and group racism was significantly higher among US-born than foreign-born Black pregnant women, with US-born women having 4.1 and 7.8 times the odds, respectively, of childhood exposure. In multivariate analyses, US-born women’s personal and group racism exposure also was more pervasive across the eight life domains we queried. Examined by immigrant subgroups, US-born women were more similar in their self-reports of racism to foreign-born women who moved to the US before age 18 than to women who immigrated after age 18. Moreover, US-born women more closely resembled foreign-born women from the Caribbean than those from Africa. Differential exposure to self-reported racism over the life course may be a critically important factor that distinguishes US-born Black women from their foreign-born counterparts. PMID:19386406
White Paper for US Space Policy Going Forward
NASA Astrophysics Data System (ADS)
Sinclair, A.
2009-04-01
White Paper for US Space Policy Going Forward In January 2009 we see both the US government and US civil society focus into the resolution of many serious problems, as we look towards a new administration for direction and initiative. Among leading factors in determining the outcomes for the years ahead will be the significant role-played by US space policy for the way forward. A policy making that will determine and address many of the attributes of the forthcoming" information age" The popular term which indicates space based communications and observation structures as providing a growing capacity for an informational and computational enabled problem solving bias. The linkage between space development and a growing information development is an issue that can reach for all levels of US civil society, offering significant educational perspectives and engaging for an immediate placement within our laptops and our on-line methodologies. Such capacity has been generally brought forward and engendered within the US by a Silicon Valley community that has initiated for both the burgeoning growth of space based communications and for the advent of the nearer affects within our everyday lives. Likewise the production of large scale computational and AI abilities shows as an outstanding and remarkable opportunity within the US technological capacities Such initiatives have been greatly advanced by US for more than thirty years, yet today despite the outreach, export and rapid expansion of US high tech industry, the US seeks new direction for clarification and provision into the further stages of US technological growth. What is that direction and how will it be obtained? Today the venue and purpose of the modern space based and information enabled assets gives a clear functionality for many global scale interchanges and dialogs. The leading factors that will enable significant US outreach into these essential global perspectives can obtain at various levels within international space policy forums. For example: International agendas for space exploration, including international lunar settlement,the preparation of an international space shuttle and an international program for meteorite mitigation. Growing capacity of earth observation facilities Development of the informational basis within the global development arenas Information enabled inter-governmental exchange and problem solving perspectives for economic, agricultural and infrastructure development. The civil society basis within e-government International Cyberspace For US engagement into the international community at the best possible levels it is essential that US Space policy consider for the global scale affects that can be undertaken within the growing information technology attributes. These initiating attributes will also be the ones that determine for fast referendums into sustainable practice, for the revisions of an industrial base, for needed infrastructures in many areas and for comprehensive levels of educational engagement into the way forward. Both within the US, and as US outreach within global dynamics. US stands to gain through the momentum into the space and information basis, but such gain will be seen as a direct result of an integrated policy making, that identifies the authentic purpose and intention of space development for a future world. The comprehensive alignment of US space policy into the national, international and global development agendas is a topic that can only be undertaken within a measure of US public engagement. Engagement which can be found within US policy making initiative, in particular through worthwhile interchange and participation with Space Agencies around the world for development of an internationalized approach. Such an internationalized approach can be for the moon and for the earth, for education,for non -proliferation, for global security, for civil society representation and for the stringent terms of a climate change. Ways and means are many and readily available ones, what is needed are not necessarily newer levels of technological innovation but the purpose and intention to guide those that already exist. In particular the administration refocus for US Space Policy will require not only a careful and well-intentioned educational and developmental bias, but also an acknowledgment of the continuing purpose of US space and technology attributes into the essential US economic dimensions. In this way obtaining a continuing and advanced technological purview for US policy and for US technological exports, as contribution for rapid global development and for the undertakings of a pacifist and secure condition.
Sivakumar, Venkatasubramanian; Swaminathan, Gopalaraman; Rao, Paruchuri Gangadhar; Muralidharan, Chellappa; Mandal, Asit Baran; Ramasami, Thirumalachari
2010-08-01
Influence of ultrasound (US) on various unit operations in leather processing has been studied with the aim to improve the process efficiency, quality, reduce process time and achieve near-zero discharge levels in effluent streams as a cleaner option. Effect of US on substrate (skin/leather) matrix as well as substances used in different unit operations have been studied and found to be useful in the processing. Absorption of US energy by leather in process vessel at different distances from US source has been measured and found to be significant. Effect of particle-size of different substances due to sonication indicates positive influence on the diffusion through the matrix. Our experimental results suggest that US effect is better realized for the cases with pronounced diffusion hindrance. Influence of US on bioprocessing of leather has been studied and found beneficial. Attempts have also been made to improve the US aided processing using external aids. Operating US in pulse mode operation could be useful in order to reduce the electrical energy consumption. Use of US has also been studied in the preparation of leather auxiliaries involving mass-transfer resistance. Preliminary cost analysis carried out for ultrasound-assisted leather-dyeing process indicates scale-up possibility. Therefore, US application provide improvement in process efficiency as well as making cleaner production methods feasible. Hence, overall results suggest that use of US in leather industry is imminent and potential viable option in near future. Copyright 2009 Elsevier B.V. All rights reserved.
Ultrasound for internal medicine physicians: the future of the physical examination.
Dulohery, Megan M; Stoven, Samantha; Kurklinsky, Andrew K; Kurklinksy, Andrew; Halvorsen, Andrew; McDonald, Furman S; Bhagra, Anjali
2014-06-01
With the advent of compact ultrasound (US) devices, it is easier for physicians to enhance their physical examinations through the use of US. However, although this new tool is widely available, few internal medicine physicians have US training. This study sought to understand physicians' baseline knowledge and skill, provide education in US principles, and demonstrate that proper use of compact US devices is a skill that can be quickly learned. Training was performed at the Mayo Clinic in June 2010 and June 2011. The participants consisted of internal medicine residents. The workshop included didactics and hands-on US experiences with human and cadaver models in a simulation center. Pretests and posttests of residents' knowledge, attitudes, and skills with US were completed. We reassessed the 2010 group in the spring of 2012 with a long-term retention survey for knowledge and confidence in viewing images. A total of 136 interns completed the workshop. Thirty-nine residents completed the long-term retention survey. Posttest assessments showed a statistically significant improvement in the knowledge of US imaging, confidence in identifying structures, image identification, and image acquisition (P < .0001). In the long-term retention study, knowledge of US imaging and confidence in identifying structures did decline. This educational intervention resulted in improvement in US knowledge and image acquisition. However, the knowledge diminished over time, suggesting that further education is needed if US is to become an important component of internal medicine training and practice. © 2014 by the American Institute of Ultrasound in Medicine.
Cumulative phase delay imaging for contrast-enhanced ultrasound tomography
NASA Astrophysics Data System (ADS)
Demi, Libertario; van Sloun, Ruud J. G.; Wijkstra, Hessel; Mischi, Massimo
2015-11-01
Standard dynamic-contrast enhanced ultrasound (DCE-US) imaging detects and estimates ultrasound-contrast-agent (UCA) concentration based on the amplitude of the nonlinear (harmonic) components generated during ultrasound (US) propagation through UCAs. However, harmonic components generation is not specific to UCAs, as it also occurs for US propagating through tissue. Moreover, nonlinear artifacts affect standard DCE-US imaging, causing contrast to tissue ratio reduction, and resulting in possible misclassification of tissue and misinterpretation of UCA concentration. Furthermore, no contrast-specific modality exists for DCE-US tomography; in particular speed-of-sound changes due to UCAs are well within those caused by different tissue types. Recently, a new marker for UCAs has been introduced. A cumulative phase delay (CPD) between the second harmonic and fundamental component is in fact observable for US propagating through UCAs, and is absent in tissue. In this paper, tomographic US images based on CPD are for the first time presented and compared to speed-of-sound US tomography. Results show the applicability of this marker for contrast specific US imaging, with cumulative phase delay imaging (CPDI) showing superior capabilities in detecting and localizing UCA, as compared to speed-of-sound US tomography. Cavities (filled with UCA) which were down to 1 mm in diameter were clearly detectable. Moreover, CPDI is free of the above mentioned nonlinear artifacts. These results open important possibilities to DCE-US tomography, with potential applications to breast imaging for cancer localization.
Cumulative phase delay imaging for contrast-enhanced ultrasound tomography.
Demi, Libertario; van Sloun, Ruud J G; Wijkstra, Hessel; Mischi, Massimo
2015-11-07
Standard dynamic-contrast enhanced ultrasound (DCE-US) imaging detects and estimates ultrasound-contrast-agent (UCA) concentration based on the amplitude of the nonlinear (harmonic) components generated during ultrasound (US) propagation through UCAs. However, harmonic components generation is not specific to UCAs, as it also occurs for US propagating through tissue. Moreover, nonlinear artifacts affect standard DCE-US imaging, causing contrast to tissue ratio reduction, and resulting in possible misclassification of tissue and misinterpretation of UCA concentration. Furthermore, no contrast-specific modality exists for DCE-US tomography; in particular speed-of-sound changes due to UCAs are well within those caused by different tissue types. Recently, a new marker for UCAs has been introduced. A cumulative phase delay (CPD) between the second harmonic and fundamental component is in fact observable for US propagating through UCAs, and is absent in tissue. In this paper, tomographic US images based on CPD are for the first time presented and compared to speed-of-sound US tomography. Results show the applicability of this marker for contrast specific US imaging, with cumulative phase delay imaging (CPDI) showing superior capabilities in detecting and localizing UCA, as compared to speed-of-sound US tomography. Cavities (filled with UCA) which were down to 1 mm in diameter were clearly detectable. Moreover, CPDI is free of the above mentioned nonlinear artifacts. These results open important possibilities to DCE-US tomography, with potential applications to breast imaging for cancer localization.
Ultrasound assisted chrome tanning: Towards a clean leather production technology.
Mengistie, Embialle; Smets, Ilse; Van Gerven, Tom
2016-09-01
Nowadays, there is a growing demand for a cleaner, but still effective alternative for production processes like in the leather industry. Ultrasound (US) assisted processing of leather might be promising in this sense. In the present paper, the use of US in the conventional chrome tanning process has been studied at different pH, temperature, tanning time, chrome dose and US exposure time by exposing the skin before tanning and during tanning operation. Both prior exposure of the skin to US and US during tanning improves the chrome uptake and reduces the shrinkage significantly. Prior exposure of the skin to US increase the chrome uptake by 13.8% or reduces the chrome dose from 8% to 5% (% based on skin weight) and shorten the process time by half while US during tanning increases the chrome uptake by 28.5% or reduces the chrome dose from 8% to 4% (half) and the tanning time to one third compared to the control without US. Concomitantly, the resulting leather quality (measured as skin shrinkage) improved from 5.2% to 3.2% shrinkage in the skin exposed to US prior tanning and to 1.3% in the skin exposed to US during the tanning experiment. This study confirms that US chrome tanning is an effective and eco-friendly tanning process which can produce a better quality leather product in a shorter process time with a lower chromium dose. Copyright © 2016 Elsevier B.V. All rights reserved.
CS Informativeness Governs CS-US Associability
Ward, Ryan D.; Gallistel, C. R.; Jensen, Greg; Richards, Vanessa L.; Fairhurst, Stephen; Balsam, Peter D
2012-01-01
In a conditioning protocol, the onset of the conditioned stimulus (CS) provides information about when to expect reinforcement (the US). There are two sources of information from the CS in a delay conditioning paradigm in which the CS-US interval is fixed. The first depends on the informativeness, the degree to which CS onset reduces the average expected time to onset of the next US. The second depends only on how precisely a subject can represent a fixed-duration interval (the temporal Weber fraction). In three experiments with mice, we tested the differential impact of these two sources of information on rate of acquisition of conditioned responding (CS-US associability). In Experiment 1, we show that associability (the inverse of trials to acquisition) increases in proportion to informativeness. In Experiment 2, we show that fixing the duration of the US-US interval or the CS-US interval or both has no effect on associability. In Experiment 3, we equated the increase in information produced by varying the C̅/T̅ ratio with the increase produced by fixing the duration of the CS-US interval. Associability increased with increased informativeness, but, as in Experiment 2, fixing the CS-US duration had no effect on associability. These results are consistent with the view that CS-US associability depends on the increased rate of reward signaled by CS onset. The results also provide further evidence that conditioned responding is temporally controlled when it emerges. PMID:22468633
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2008
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Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2003
View the 2005 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2003.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2007
View the 2009 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2007.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2005
View the 2007 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2005.
23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes
Code of Federal Regulations, 2014 CFR
2014-04-01
.... (Excepted under 23 CFR 658.11(f)). Colorado No additional routes have been federally designated; under State... State Line US 74 Monroe. NC 4 I-95 Gold Rock US 301 Battleboro. NC 11 US 70 Kinston US 264 Greenville...
23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes
Code of Federal Regulations, 2013 CFR
2013-04-01
.... (Excepted under 23 CFR 658.11(f)). Colorado No additional routes have been federally designated; under State... State Line US 74 Monroe. NC 4 I-95 Gold Rock US 301 Battleboro. NC 11 US 70 Kinston US 264 Greenville...
23 CFR Appendix A to Part 658 - National Network-Federally-Designated Routes
Code of Federal Regulations, 2012 CFR
2012-04-01
.... (Excepted under 23 CFR 658.11(f)). Colorado No additional routes have been federally designated; under State... State Line US 74 Monroe. NC 4 I-95 Gold Rock US 301 Battleboro. NC 11 US 70 Kinston US 264 Greenville...
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2000
View the 2002 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2000.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-1996
View the 1998 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 1996.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2011
View the 2013 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2011.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2012
View the 2014 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2012.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2004
View the 2006 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2004.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-1997
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Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-1998
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Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2002
View the 2004 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2002.
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-1999
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U.S. advanced launch vehicle technology programs : Quarterly Launch Report : special report
DOT National Transportation Integrated Search
1996-01-01
U.S. firms and U.S. government agencies are jointly investing in advanced launch vehicle technology. This Special Report summarizes U.S. launch vehicle technology programs and highlights the changing : roles of government and industry players in pick...
Inventory of U.S. Greenhouse Gas Emissions and Sinks: 1990-2006
View the 2008 U.S. Greenhouse Gas Inventory developed by the U.S. Government to meet U.S. commitments under the Framework Convention on Climate Change (UNFCCC). This version of the inventory covers the period from 1990 to 2006.