Foundation and Development of Local Trimble User Groups: Perspectives from the Beginning
NASA Technical Reports Server (NTRS)
Duncan, Brean W.
1996-01-01
Trimble Navigation was one of the original contractors building military grade GPS receivers and has been a dominant manufacturer in the civilian market. Two Trimble user groups have been formed. By participating in GPS user groups, members become more aware of GPS capabilities and opportunities, meet people with similar interests and needs, expand business opportunities, and provide Trimble with valuable information needed to engineer better GPS equipment.
2012-04-25
Virginia Tech VAL. Because of the excellent performance of the Trimble-based systems that were tested in the past, the Trimble subsidy Applanix was...initially contacted for available systems. The lowest cost, turnkey Trimble/ Applanix the POS LV 210 far exceeded the performance requirements of the
Geometric validation of a mobile laser scanning system for urban applications
NASA Astrophysics Data System (ADS)
Guan, Haiyan; Li, Jonathan; Yu, Yongtao; Liu, Yan
2016-03-01
Mobile laser scanning (MLS) technologies have been actively studied and implemented over the past decade, as their application fields are rapidly expanding and extending beyond conventional topographic mapping. Trimble's MX-8, as one of the MLS systems in the current market, generates rich survey-grade laser and image data for urban surveying. The objective of this study is to evaluate whether Trimble MX-8 MLS data satisfies the accuracy requirements of urban surveying. According to the formula of geo-referencing, accuracies of navigation solution and laser scanner determines the accuracy of the collected LiDAR point clouds. Two test sites were selected to test the performance of Trimble MX-8. Those extensive tests confirm that Trimble MX-8 offers a very promising tool to survey complex urban areas.
Dr. Ted Trimble: Why I Do Cancer Research
In a video, Dr. Ted Trimble talks about the importance of cancer research. World Cancer Research Day commemorates the important role research and cancer researchers play in reducing the global burden of cancer.
Trimble Use Case Information : A Presentation to DOT Adjacent Band Compatibility Workshop #2
DOT National Transportation Integrated Search
2014-12-04
Trimble Use Case Overview: Heavy Civil Construction - Planning, Designing, Building and Operating: Enhanced information, decision making and control across the entire project lifecycle, generating benefits including: - Faster Completion - Reduced Fue...
Transition of NOAA's GPS-Met Data Acquisition and Processing System to the Commercial Sector
NASA Astrophysics Data System (ADS)
Jackson, M. E.; Holub, K.; Callahan, W.; Blatt, S.
2014-12-01
In April of 2014, NOAA/OAR/ESRL Global Systems Division (GSD) and Trimble, in collaboration with Earth Networks, Inc. (ENI) signed a Cooperative Research and Development Agreement (CRADA) to transfer the existing NOAA GPS-Met Data Acquisition and Processing System (GPS-Met DAPS) technology to a commercial Trimble/ENI partnership. NOAA's GPS-Met DAPS is currently operated in a pseudo-operational mode but has proven highly reliable and running at over 95% uptime. The DAPS uses the GAMIT software to ingest dual frequency carrier phase GPS/GNSS observations and ancillary information such as real-time satellite orbits to estimate the zenith-scaled tropospheric (ZTD) signal delays and, where surface MET data are available, retrieve integrated precipitable water vapor (PWV). The NOAA data and products are made available to end users in near real-time. The Trimble/ENI partnership will use the Trimble Pivot™ software with the Atmosphere App to calculate zenith tropospheric (ZTD), tropospheric slant delay, and integrated precipitable water vapor (PWV). Evaluation of the Trimble software is underway starting with a comparison of ZTD and PWV values determined from GPS stations located near NOAA Radiosonde Observation (Upper-Air Observation) launch sites. A success metric was established that requires Trimble's PWV estimates to match ESRL/GSD's to within 1.5 mm 95% of the time, which corresponds to a ZTD uncertainty of less than 10 mm 95% of the time. Initial results indicate that Trimble/ENI data meet and exceed the ZTD metric, but for some stations PWV estimates are out of specification. These discrepancies are primarily due to how offsets between MET and GPS stations are handled and are easily resolved. Additional test networks are proposed that include low terrain/high moisture variability stations, high terrain/low moisture variability stations, as well as high terrain/high moisture variability stations. We will present results from further testing along with a timeline for the transition of the GPS-Met DAPS to an operational commercial service.
Preschool Guidelines: Rural Model (Trimble Local School District).
ERIC Educational Resources Information Center
Ohio State Dept. of Education, Columbus. Div. of Educational Services.
The purpose of this handbook is to guide rural school districts intending to establish a preschool program. The program described was established in the Trimble Local School District in the rural Appalachian area of northern Athens County, the third poorest district in Ohio. Contents concern: (1) the district's beliefs about children; (2)…
Dadwal, Himani; Shanmugasundaram, S; Krishnakumar Raja, V B
2015-09-01
To determine the rate of complications and occurrence of pterygoid plate fractures comparing two techniques of Le Fort I osteotomy i.e., Classic Pterygomaxillary Dysjunction technique and Trimble technique and to know whether the dimensions of pterygomaxillary junction [determined preoperatively by computed tomography (CT) scan] have any influence on pterygomaxillary separation achieved during surgery. The study group consisted of eight South Indian patients with maxillary excess. A total of 16 sides were examined by CT. Preoperative CT was analyzed for all the patients. The thickness and width of the pterygomaxillary junction and the distance of the greater palatine canal from the pterygomaxillary junction was noted. Pterygomaxillary dysjunction was achieved by two techniques, the classic pterygomaxillary dysjunction technique (Group I) and Trimble technique (Group II). Patients were selected randomly and equally for both the techniques. Dysjunction was analyzed by postoperative CT. The average thickness of the pterygomaxillary junction on 16 sides was 4.5 ± 1.2 mm. Untoward pterygoid plate fractures occurred in Group I in 3 sides out of 8. In Trimble technique (Group II), no pterygoid plate fractures were noted. The average width of the pterygomaxillary junction was 7.8 ± 1.5 mm, distance of the greater palatine canal from pterygomaxillary junction was 7.4 ± 1.6 mm and the length of fusion of pterygomaxillary junction was 8.0 ± 1.9 mm. The Le Fort I osteotomy has become a standard procedure for correcting various dentofacial deformities. In an attempt to make Le Fort I osteotomy safer and avoid the problems associated with sectioning with an osteotome between the maxillary tuberosity and the pterygoid plates, Trimble suggested sectioning across the posterior aspect of the maxillary tuberosity itself. In our study, comparison between the classic pterygomaxillary dysjunction technique and the Trimble technique was made by using postoperative CT scan. It was found that unfavorable pterygoid plate fractures occurred only in dysjunction group and not in Trimble technique group. Preoperative CT scan assessment was done for all the patients to determine the dimension of the pterygomaxillary region. Preoperative CT scan proved to be helpful in not only determining the dimensions of the pterygomaxillary region but we also found out that thickness of the pterygomaxillary junction was an important parameter which may influence the separation at the pterygomaxillary region. No untoward fractures of the pterygoid plates were seen in Trimble technique (Group II) which makes it a safer technique than classic dysjunction technique. It was noted that pterygoid plate fractures occurred in patients in whom the thickness of the pterygomaxillary junction was <3.6 mm (preoperatively). Therefore, preoperative evaluation is important, on the basis of which we can decide upon the technique to be selected for safer and acceptable separation of pterygomaxillary region.
NASA Astrophysics Data System (ADS)
Jackson, Michael; Blatt, Stephan; Holub, Kirk
2015-04-01
In April of 2014, NOAA/OAR/ESRL Global Systems Division (GSD) and Trimble, in collaboration with Earth Networks, Inc. (ENI) signed a Cooperative Research and Development Agreement (CRADA) to transfer the existing NOAA GPS-Met Data Acquisition and Processing System (GPS-Met DAPS) technology to a commercial Trimble/ENI partnership. NOAA's GPS-Met DAPS is currently operated in a pseudo-operational mode but has proven highly reliable and running at over 95% uptime. The DAPS uses the GAMIT software to ingest dual frequency carrier phase GPS/GNSS observations and ancillary information such as real-time satellite orbits to estimate the zenith-scaled tropospheric (ZTD) signal delays and, where surface MET data are available, retrieve integrated precipitable water vapor (PWV). The NOAA data and products are made available to end users in near real-time. The Trimble/ENI partnership will use the Trimble Pivot™ software with the Atmosphere App to calculate zenith tropospheric (ZTD), tropospheric slant delay, and integrated precipitable water vapor (PWV). Evaluation of the Trimble software is underway starting with a comparison of ZTD and PWV values determined from four sub networks of GPS stations located 1. near NOAA Radiosonde Observation (Upper-Air Observation) launch sites; 2. Stations with low terrain/high moisture variability (Gulf Coast); 3. Stations with high terrain/low moisture variability (Southern California); and 4. Stations with high terrain/high moisture variability (high terrain variability elev. > 1000m). For each network GSD and T/ENI run the same stations for 30 days, compare results, and perform an evaluation of the long-term solution accuracy, precision and reliability. Metrics for success include T/ENI PWV estimates within 1.5 mm of ESRL/GSD's estimates 95% of the time (ZTD uncertainty of less than 10 mm 95% of the time). The threshold for allowable variations in ZTD between NOAA GPS-Met and T/ENI processing are 10mm. The CRADA 1&2 Trimble processing show a variation of 4±2mm and 3±8mm respectively. The threshold for allowable variations in PWV between NOAA GPS-Met and T/ENI processing are 15mm. The CRADA 1&2 Trimble processing show a variation of 2±4mm and 10±13 respectively. The T/ENI PWV and ZTD values meet and exceed the requirements outlined in the CRADA for the first two networks processed. T/ENI Partnership brings a footprint of GNSS and meteorological stations that could significantly enhance the latency, temporal, and geographic density of ZTD and PWV over the US and Europe. We will provide a brief overview of the Trimble Pivot™ software and the Atmosphere App and present results from further testing along with a timeline for the transition of the GPS-Met DAPS to an operational commercial service.
Sediment Management at the Watershed Level
2012-08-01
al. 2005). Trimble examined ten river basins (1,000 to 7,500 mi2 ) and found that the sediment yield averaged about six percent. He attributed the...importance of storage and remobilization in controlling sediment yield from the 139 mi2 Coon Creek watershed in Wisconsin. Trimble prepared sediment...Federal government in 1984, DHP activities targeted sixteen watersheds comprising 2,625 mi2 within the Yazoo River Basin in the Lower Mississippi
NASA Astrophysics Data System (ADS)
Hlotov, Volodymyr; Hunina, Alla; Siejka, Zbigniew
2017-06-01
The main purpose of this work is to confirm the possibility of making largescale orthophotomaps applying unmanned aerial vehicle (UAV) Trimble- UX5. A planned altitude reference of the studying territory was carried out before to the aerial surveying. The studying territory has been marked with distinctive checkpoints in the form of triangles (0.5 × 0.5 × 0.2 m). The checkpoints used to precise the accuracy of orthophotomap have been marked with similar triangles. To determine marked reference point coordinates and check-points method of GNSS in real-time kinematics (RTK) measuring has been applied. Projecting of aerial surveying has been done with the help of installed Trimble Access Aerial Imaging, having been used to run out the UX5. Aerial survey out of the Trimble UX5 UAV has been done with the help of the digital camera SONY NEX-5R from 200m and 300 m altitude. These aerial surveying data have been calculated applying special photogrammetric software Pix 4D. The orthophotomap of the surveying objects has been made with its help. To determine the precise accuracy of the got results of aerial surveying the checkpoint coordinates according to the orthophotomap have been set. The average square error has been calculated according to the set coordinates applying GNSS measurements. A-priori accuracy estimation of spatial coordinates of the studying territory using the aerial surveying data have been calculated: mx=0.11 m, my=0.15 m, mz=0.23 m in the village of Remeniv and mx=0.26 m, my=0.38 m, mz=0.43 m in the town of Vynnyky. The accuracy of determining checkpoint coordinates has been investigated using images obtained out of UAV and the average square error of the reference points. Based on comparative analysis of the got results of the accuracy estimation of the made orthophotomap it can be concluded that the value the average square error does not exceed a-priori accuracy estimation. The possibility of applying Trimble UX5 UAV for making large-scale orthophotomaps has been investigated. The aerial surveying output data using UAV can be applied for monitoring potentially dangerous for people objects, the state border controlling, checking out the plots of settlements. Thus, it is important to control the accuracy the got results. Having based on the done analysis and experimental researches it can be concluded that applying UAV gives the possibility to find data more efficiently in comparison with the land surveying methods. As the result, the Trimble UX5 UAV gives the possibility to survey built-up territories with the required accuracy for making orthophotomaps with the following scales 1: 2000, 1: 1000, 1: 500.
First Experiences with the Trimble SX10 Scanning Total Station for Building Facade Survey
NASA Astrophysics Data System (ADS)
Lachat, E.; Landes, T.; Grussenmeyer, P.
2017-02-01
The use of Terrestrial Laser Scanner (TLS) tends to become a solution in many research areas related to large scale surveying. Meanwhile, the technological advances combined with the investigation of user needs have brought to the design of innovative devices known as scanning total stations. Such instruments merge in a unique hardware both scanning and surveying facilities. Even if their scanning rate is often reduced compared to conventional TLS, they make it possible to directly georeference laser scanning projects and to complete them with measurements of individual points of interest. The recent Trimble SX10 which was launched on the market in early October 2016 has been tested and some experiences carried out with it are reported in this paper. The analyses mainly focus on the survey of a building facade. Next to laser scanning survey, a photogrammetry campaign using an Unmanned Aerial Vehicle (UAV) has been carried out. These different datasets are used to assess the Trimble SX10 issued point clouds through a set of comparisons. Since georeferencing is possible either directly or indirectly using this device, data processed both ways are also compared to conclude about the more reliable method.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Entz, Ray; Lockwood, Jr., Neil; Holmes, Darren
2003-10-01
In 2000 and 2001, the Kalispel Natural Resource Department (KNRD) continued to mitigate the wildlife habitat losses as part of the Albeni Falls Wildlife Mitigation Project. Utilizing Bonneville Power Administration (BPA) funds, the Kalispel Tribe of Indians (Tribe) purchased three projects totaling nearly 1,200 acres. The Tacoma/Trimble Wildlife Management Area is a conglomeration of properties now estimated at 1,700 acres. It is the Tribe's intent to manage these properties in cooperation and collaboration with the Pend Oreille County Public Utility District (PUD) No. 1 and the U.S. Fish and Wildlife Service (USFWS) to benefit wildlife habitats and associated species, populations,more » and guilds.« less
Investigation of a Combined Surveying and Scanning Device: The Trimble SX10 Scanning Total Station
Lachat, Elise; Landes, Tania; Grussenmeyer, Pierre
2017-01-01
Surveying fields from geosciences to infrastructure monitoring make use of a wide range of instruments for accurate 3D geometry acquisition. In many cases, the Terrestrial Laser Scanner (TLS) tends to become an optimal alternative to total station measurements thanks to the high point acquisition rate it offers, but also to ever deeper data processing software functionalities. Nevertheless, traditional surveying techniques are valuable in some kinds of projects. Nowadays, a few modern total stations combine their conventional capabilities with those of a laser scanner in a unique device. The recent Trimble SX10 scanning total station is a survey instrument merging high-speed 3D scanning and the capabilities of an image-assisted total station. In this paper this new instrument is introduced and first compared to state-of-the-art image-assisted total stations. The paper also addresses the topic of various laser scanning projects and the delivered point clouds are compared with those of other TLS. Directly and indirectly georeferenced projects have been carried out and are investigated in this paper, and a polygonal traverse is performed through a building. Comparisons with the results delivered by well-established survey instruments show the reliability of the Trimble SX10 for geodetic work as well as for scanning projects. PMID:28362319
NASA Astrophysics Data System (ADS)
Siejka, Zbigniew
2014-12-01
The paper presents the method of satellite measurements, which gives users the ability of GNSS continuous precise positioning in real time, even in the case of short interruptions in receiving the correction of the local ground system of measurements support. The proposed method is a combination of two satellite positioning technologies RTN GNSS and RTX Extended. In technology RTX Extended the xFill function was used for precise positioning in real time and in the local reference system. This function provides the ability to perform measurement without the need for constant communication with the ground support satellite system. Test measurements were performed on a test basis located in Krakow, and RTN GNSS positioning was done based on the national network of reference stations of the ASGEUPOS. The solution allows for short (up to 5 minutes) interruptions in radio or internet communication. When the primary stream of RTN correction is not available, then the global corrections Trimble xFill broadcasted by satellite are used. The new technology uses in the real-time data from the global network of tracking stations and contributes significantly to improving the quality and efficiency of surveying works. At present according to the authors, technology Trimble CenterPoint RTX can guarantee repeatability of measurements not worse than 3.8 cm (Trimble Survey Division, 2012). In the paper the comparative analysis of measurement results between the two technologies was performed: RTN carried out in the classic way, which was based on the corrections of the terrestrial local network of the Polish system of active geodetic network (ASG-EUPOS) and RTK xFill technology. The results were related to the data of test network, established as error free. The research gave satisfactory results and confirmed the great potential of the use of the new technology in the geodetic work realization. By combining these two technologies of GNSS surveying the user can greatly improve the overall performance of real-time positioning.
Geologic map of the greater Denver area, Front Range urban corridor, Colorado
Trimble, Donald E.; Machette, Michael N.
1979-01-01
This digital map shows the areal extent of surficial deposits and rock stratigraphic units (formations) as compiled by Trimble and Machette from 1973 to 1977 and published in 1979 under the Front Range Urban Corridor Geology Program. Trimble and Machette compiled their geologic map from published geologic maps and unpublished geologic mapping having varied map unit schemes. A convenient feature of the compiled map is its uniform classification of geologic units that mostly matches those of companion maps to the north (USGS I-855-G) and to the south (USGS I-857-F). Published as a color paper map, the Trimble and Machette map was intended for land-use planning in the Front Range Urban Corridor. This map recently (1997-1999) was digitized under the USGS Front Range Infrastructure Resources Project. In general, the mountainous areas in the western part of the map exhibit various igneous and metamorphic bedrock units of Precambrian age, major faults, and fault brecciation zones at the east margin (5-20 km wide) of the Front Range. The eastern and central parts of the map (Colorado Piedmont) depict a mantle of unconsolidated deposits of Quaternary age and interspersed outcroppings of Cretaceous or Tertiary-Cretaceous sedimentary bedrock. The Quaternary mantle comprises eolian deposits (quartz sand and silt), alluvium (gravel, sand, and silt of variable composition), colluvium, and a few landslides. At the mountain front, north-trending, dipping Paleozoic and Mesozoic sandstone, shale, and limestone bedrock formations form hogbacks and intervening valleys.
Trimble, Donald E.; Machette, Michael N.; Brandt, Theodore R.; Moore, David W.; Murray, Kyle E.
2003-01-01
This digital map shows bedding attitude symbols display over the geographic extent of surficial deposits and rock stratigraphic units (formations) as compiled by Trimble and Machette 1973-1977 and published in 1979 (U.S. Geological Survey Map I-856-H) under the Front Range Urban Corridor Geology Program. Trimble and Machette compiled their geologic map from published geologic maps and unpublished geologic mapping having varied map unit schemes. A convenient feature of the compiled map is its uniform classification of geologic units that mostly matches those of companion maps to the north (USGS I-855-G) and to the south (USGS I-857-F). Published as a color paper map, the Trimble and Machette map was intended for land-use planning in the Front Range Urban Corridor. This map recently (1997-1999), was digitized under the USGS Front Range Infrastructure Resources Project (see cross-reference). In general, the mountainous areas in the west part of the map exhibit various igneous and metamorphic bedrock units of Precambrian age, major faults, and fault brecciation zones at the east margin (5-20 km wide) of the Front Range. The eastern and central parts of the map (Colorado Piedmont) depict a mantle of unconsolidated deposits of Quaternary age and interspersed outcroppings of Cretaceous or Tertiary-Cretaceous sedimentary bedrock. The Quaternary mantle is comprised of eolian deposits (quartz sand and silt), alluvium (gravel, sand, and silt of variable composition), colluvium, and few landslides. At the mountain front, north-trending, dipping Paleozoic and Mesozoic sandstone, shale, and limestone bedrock formations form hogbacks and intervening valleys.
Accuracy of tracking forest machines with GPS
M.W. Veal; S.E. Taylor; T.P. McDonald; D.K. McLemore; M.R. Dunn
2001-01-01
This paper describes the results of a study that measured the accuracy of using GPS to track movement of forest machines. Two different commercially available GPS receivers (Trimble ProXR and GeoExplorer II) were used to track\\r\
Oregon Cascades Play Fairway Analysis: Maps
Trimble, John
2015-12-15
The maps in this submission include: heat flow, alkalinity, Cl, Mg, SiO2, Quaternary volcanic rocks, faults, and land ownership. All of the Oregon Cascade region. The work was done by John Trimble, in 2015, at Oregon State University.
NASA Astrophysics Data System (ADS)
Braun, Jaroslav; Štroner, Martin; Urban, Rudolf
2015-05-01
All surveying instruments and their measurements suffer from some errors. To refine the measurement results, it is necessary to use procedures restricting influence of the instrument errors on the measured values or to implement numerical corrections. In precise engineering surveying industrial applications the accuracy of the distances usually realized on relatively short distance is a key parameter limiting the resulting accuracy of the determined values (coordinates, etc.). To determine the size of systematic and random errors of the measured distances were made test with the idea of the suppression of the random error by the averaging of the repeating measurement, and reducing systematic errors influence of by identifying their absolute size on the absolute baseline realized in geodetic laboratory at the Faculty of Civil Engineering CTU in Prague. The 16 concrete pillars with forced centerings were set up and the absolute distances between the points were determined with a standard deviation of 0.02 millimetre using a Leica Absolute Tracker AT401. For any distance measured by the calibrated instruments (up to the length of the testing baseline, i.e. 38.6 m) can now be determined the size of error correction of the distance meter in two ways: Firstly by the interpolation on the raw data, or secondly using correction function derived by previous FFT transformation usage. The quality of this calibration and correction procedure was tested on three instruments (Trimble S6 HP, Topcon GPT-7501, Trimble M3) experimentally using Leica Absolute Tracker AT401. By the correction procedure was the standard deviation of the measured distances reduced significantly to less than 0.6 mm. In case of Topcon GPT-7501 is the nominal standard deviation 2 mm, achieved (without corrections) 2.8 mm and after corrections 0.55 mm; in case of Trimble M3 is nominal standard deviation 3 mm, achieved (without corrections) 1.1 mm and after corrections 0.58 mm; and finally in case of Trimble S6 is nominal standard deviation 1 mm, achieved (without corrections) 1.2 mm and after corrections 0.51 mm. Proposed procedure of the calibration and correction is in our opinion very suitable for increasing of the accuracy of the electronic distance measurement and allows the use of the common surveying instrument to achieve uncommonly high precision.
Publications - GMC 214 | Alaska Division of Geological & Geophysical
Chevron USA Inc. OCS Y-0996-1 (Diamond #1) well Authors: Unknown Publication Date: 1993 Publisher: Alaska see our publication sales page for more information. Bibliographic Reference Unknown, 1993, Vitrinite
Louisville Gas & Electric Trimble Power Station; Petition to Object to REVISED Title V Permit
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database.
Integrating Archaeological Modeling in DoD Cultural Resource Compliance
2012-10-26
Leo 2001 Random Forests. Machine Learning 45:5–32. Briuer, Frederick, Clifford Brown, Alan Gillespie, Fredrick Limp, Michael Trimble, and Len...glaciolacustrine clays on glacial lake plains Inceptisols Very-fine, mixed, active, nonacid, mesic Mollic Endoaquepts Low to none LoC Lowville silt
Fajardo, Geroncio C; Posid, Joseph; Papagiotas, Stephen; Lowe, Luis
2015-01-01
There have been periodic electronic news media reports of potential bioterrorism-related incidents involving unknown substances (often referred to as "white powder") since the 2001 intentional dissemination of Bacillus anthracis through the U.S. Postal System. This study reviewed the number of unknown "white powder" incidents reported online by the electronic news media and compared them with unknown "white powder" incidents reported to the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Federal Bureau of Investigation (FBI) during a 2-year period from June 1, 2009 and May 31, 2011. Results identified 297 electronic news media reports, 538 CDC reports, and 384 FBI reports of unknown "white powder." This study showed different unknown "white powder" incidents captured by each of the three sources. However, the authors could not determine the public health implications of this discordance. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
Using Google SketchUp to simulate tree row azimuth effects on alley shading
USDA-ARS?s Scientific Manuscript database
Effect of row azimuth on alley crop illumination is difficult to determine empirically. Our objective was to determine if Google SketchUp (Trimble Inc., Sunnyvale, CA) could be used to simulate effect of azimuth orientation on illumination of loblolly pine (Pinus taeda L.) alleys. Simulations were...
NCI and the Chinese National Cancer Center pursue new collaborations in cancer research
CGH Director, Dr. Ted Trimble, and East Asia Program Director, Dr. Ann Chao, traveled to Beijing with Mr. Matthew Brown from the Department of Health and Human Services Office of Global Affairs to attend the Joint Meeting of the NCC and the U.S. NCI.
The Nature and Significance of Surveys
NASA Astrophysics Data System (ADS)
Trimble, V.
We present here some of the ideas and questions mentioned by the panelists and other participants during the discussion that immediately preceded Ofer Lahav's concluding remarks. Official panelists were George Djorgovski, Michael Disney, Ofer Lahav, and Virginia Trimble (chair). The topics of the posters are very briefly summarized as well.
... 401. CrossRef PubMed Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR, et al. ... 805. CrossRef PubMed Schmidt MI, Duncan BB, Sharrett AR, Lindberg G, Savage PJ, Offenbacher S, et al. Markers ...
2007-03-01
instrumentation was provided under a cooperative agreement with the Applanix Systems Integration Group (ASIG), a subsidiary of the Trimble Corporation. This MSI...system (Digital Sensor System; http://www.applanix.com/products/dss index.php) was provided as part of the Applanix Position and Orientation System (POS
ERIC Educational Resources Information Center
Osman, Abdulaziz
2016-01-01
The purpose of this research study was to examine the unknown fears of embracing cloud computing which stretches across measurements like fear of change from leaders and the complexity of the technology in 9-1-1 dispatch centers in USA. The problem that was addressed in the study was that many 9-1-1 dispatch centers in USA are still using old…
Mesas-Carrascosa, Francisco-Javier; Notario García, María Dolores; Meroño de Larriva, Jose Emilio; García-Ferrer, Alfonso
2016-11-01
This article describes the configuration and technical specifications of a multi-rotor unmanned aerial vehicle (UAV) using a red-green-blue (RGB) sensor for the acquisition of images needed for the production of orthomosaics to be used in archaeological applications. Several flight missions were programmed as follows: flight altitudes at 30, 40, 50, 60, 70 and 80 m above ground level; two forward and side overlap settings (80%-50% and 70%-40%); and the use, or lack thereof, of ground control points. These settings were chosen to analyze their influence on the spatial quality of orthomosaicked images processed by Inpho UASMaster (Trimble, CA, USA). Changes in illumination over the study area, its impact on flight duration, and how it relates to these settings is also considered. The combined effect of these parameters on spatial quality is presented as well, defining a ratio between ground sample distance of UAV images and expected root mean square of a UAV orthomosaick. The results indicate that a balance between all the proposed parameters is useful for optimizing mission planning and image processing, altitude above ground level (AGL) being main parameter because of its influence on root mean square error (RMSE).
Mesas-Carrascosa, Francisco-Javier; Notario García, María Dolores; Meroño de Larriva, Jose Emilio; García-Ferrer, Alfonso
2016-01-01
This article describes the configuration and technical specifications of a multi-rotor unmanned aerial vehicle (UAV) using a red–green–blue (RGB) sensor for the acquisition of images needed for the production of orthomosaics to be used in archaeological applications. Several flight missions were programmed as follows: flight altitudes at 30, 40, 50, 60, 70 and 80 m above ground level; two forward and side overlap settings (80%–50% and 70%–40%); and the use, or lack thereof, of ground control points. These settings were chosen to analyze their influence on the spatial quality of orthomosaicked images processed by Inpho UASMaster (Trimble, CA, USA). Changes in illumination over the study area, its impact on flight duration, and how it relates to these settings is also considered. The combined effect of these parameters on spatial quality is presented as well, defining a ratio between ground sample distance of UAV images and expected root mean square of a UAV orthomosaick. The results indicate that a balance between all the proposed parameters is useful for optimizing mission planning and image processing, altitude above ground level (AGL) being main parameter because of its influence on root mean square error (RMSE). PMID:27809293
USDA-ARS?s Scientific Manuscript database
Presentation of a comprehensive checklist of the copepod fauna of Wyoming, USA with 41 species of copepods; based on museum specimens, literature reviews, and active surveillance. Of these species 19 were previously unknown from the state. This checklist includes species in the families Centropagida...
Air Force Internal Control Systems: A Proposal for Improvement.
1986-09-01
Wrong. Idea Paper, LD 51636A, PMCS 82-C, August 1982. 66. Marler , Kenneth E. Implementation of the Federal Managers’ Financial Integrity Act of 1982 in... Eric V. Can Internal Review Support A Manage- ment Development Program? Idea Paper, LD 47951A, PMCS 81-A, December 1980. 91. Trimble, Robert C., Jr
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database.
77 FR 2557 - National Cancer Institute; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-18
... 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose... Subcommittee on Global Cancer Research. Open: February 27, 2012, 6:30 p.m. to 8 p.m. Agenda: Discussion on.... Contact Person: Dr. Ted Trimble, Executive Secretary, NCAB Ad hoc Subcommittee on Global Cancer Research...
76 FR 66733 - National Cancer Institute; Notice of Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-27
... 552b(c)(6), Title 5 U.S.C., as amended for the review, discussion, and evaluation of individual... Cancer Advisory Board, Subcommittee on Global Cancer Research. Open: December 5, 2011, 6:30 p.m. to 8 p.m.... Contact Person: Dr. Ted Trimble, Executive Secretary, NCAB Subcommittee on Global Cancer Research...
Accuracy of Tracking Forest Machines with GPS
M.W. Veal; S.E. Taylor; T.P. McDonald; D.K. McLemore; M.R. Dunn
2001-01-01
This paper describes the results of a study that measured the accuracy of using GPS to track movement offorest machines. Two different commercially available GPS receivers (Trimble ProXR and GeoExplorer II) were used to track wheeled skidders under three different canopy conditions at two different vehicle speeds. Dynamic GPS data were compared to position data...
Defense Innovation Unit Experimental (DIUX): Innovative or Excessive
2017-04-06
DIUx, and the short history of DIUx. Innovation principles from authors Vijay Govindarajan, Michael Docherty, and Clayton Christensen are then...innovation principles such as performance engine & innovative team, collective / open innovation, and disruptive technology and its implications – is...various innovation principles drawing primarily from work by authors Vijay Govindarajan and Chris Trimble, Michael Docherty, and Clayton Christenson
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database.
Innovative Navigation Systems to Support Digital Geophysical Mapping
2004-02-01
9 Figure 8. Blackhawk/ Applanix GPS/INS System.................................................................10 Figure 9. Figure-Eight Traverse...Vulcan/LaserStation Line-of-sight laser Parsons Trimble INS/GPS DGPS and inertia guidance Blackhawk Applanix INS/GPS DGPS and inertia guidance...The Applanix Positioning and Orientation System for Land Survey (POS/LS) was used for the Phase I work. The system is similar to the Parsons
Botulism mortality in the USA, 1975–2009
Jackson, Kelly A.; Mahon, Barbara E.; Copeland, John; Fagan, Ryan P.
2017-01-01
Botulism had mortality rates >60% before the 1950s. We reviewed confirmed botulism cases in the USA during 1975–2009 including infant, foodborne, wound, and other/unknown acquisition categories, and calculated mortality ratios. We created a multivariate logistic regression model for non-infant cases (foodborne, wound, and other/unknown). Overall mortality was 3.0% with 109 botulism-related deaths among 3,618 botulism cases [18 (<1%) deaths among 2,352 infant botulism cases, 61 (7.1%) deaths among 854 foodborne botulism cases, 18 (5.0%) deaths among 359 wound botulism cases, and 12 (22.6%) deaths among 53 other/unknown botulism cases]. Mortality among all cases increased with age; it was lowest among infants (0.8%) and highest among persons ≥80 years old (34.4%). Toxin type F had higher mortality (13.8%) than types A, B, or E (range, 1.4% to 4.1%). Efforts to reduce botulism mortality should target non-infant transmission categories and older adults. PMID:28603554
NASA Astrophysics Data System (ADS)
Berglund, H. T.; Hodgkinson, K. M.; Blume, F.; Mencin, D.; Phillips, D. A.; Meertens, C. M.; Mattioli, G. S.
2014-12-01
The GAGE Facility, managed by UNAVCO, operates a real-time GNSS (RT-GNSS) network of ~450 stations. The majority of the streaming stations are part of the EarthScope Plate Boundary Observatory (PBO). Following community input from a real-time GNSS data products and formats meeting hosted by UNAVCO in Spring of 2011, UNAVCO now provides real-time PPP positions, and network solutions where practical, for all available stations using Trimble's PIVOT RTX server software and TrackRT. The UNAVCO real-time system has the potential to enhance our understanding of earthquakes, seismic wave propagation, volcanic eruptions, magmatic intrusions, movement of ice, landslides, and the dynamics of the atmosphere. Beyond the ever increasing applications in science and engineering, RT-GNSS has the potential to provide early warning of hazards to emergency managers, utilities, other infrastructure managers, first responders and others. Upgrades to the network include eight Trimble NetR9 GNSS receivers with GLONASS and receiver-based RTX capabilities and sixteen new co-located MEMS based accelerometers. These new capabilities will allow integration of GNSS and strong motion data to produce broad-spectrum waveforms improving Earthquake Early Warning systems. Controlled outdoor kinematic and static experiments provide a useful method for evaluating and comparing real-time systems. UNAVCO has developed a portable low-cost antenna actuator to characterize the kinematic performance of receiver- and server-based real-time positioning algorithms and identify system limitations. We have performed tests using controlled 1-d antenna motions and will present comparisons between these and other post-processed kinematic algorithms including GIPSY-OASIS and TRACK. In addition to kinematic testing, long-term static testing of Trimble's RTX service is ongoing at UNAVCO and will be used to characterize the stability of the position time-series produced by RTX. In addition, with the goal of characterizing stability and improving software and higher level products based on real-time and high frequency GNSS time series, we present an overview of the UNAVCO RT-GPS system, a comparison of the UNAVCO generated real-time, static and community data products, and an overview of available common data sets.
NASA Astrophysics Data System (ADS)
Blume, F.; Berglund, H. T.
2016-12-01
In 2012 the Federal Communications Commission (FCC) reversed its decision to allow communications company LightSquared to use GPS-adjacent spectrum for a ground based network after testing demonstrated harmful interference to GPS receivers. Now rebranded as Ligado, they have submitted modified application to use a smaller portion of the L-band spectrum at much lower power. Many GPS community stakeholders, including the hazard monitoring and EEW communities remain concerned that Ligado's proposed use could still cause harmful interference, causing signal degradation, real-time positioning errors, and total failure of GNSS hardware in widespread use in hazard monitoring networks. The Department of Transportation (DoT) has conducted hardware tests to determine adjacent-band transmitter power limit criteria that would prevent harmful interference from Ligado's operations. We present preliminary results produced from the data collected by the three UNAVCO receiver types tested: Trimble NetRS, Trimble NetR9, and Septentrio PolaRx5. In the first round of testing, simulated GNSS signals were broadcast in an anechoic chamber (pictured below) while interfering signals are broadcast simultaneously with varying amplitude and frequency. The older GPS-only NetRS receiver showed smaller reductions in SNR at frequencies adjacent to GPS L1 as compared to the other receivers, suggesting narrower L1 filter bandwidth in the RF frontend. The NetR9 showed greater decreases in observed SNR in the 1615 to 1625 MHz range when compared to the other two receivers. This suggests that the NetR9's L1 filter bandwidth has been increased to accommodate GNSS signals. Linearity tests were conducted to better relate SNR measurements between receiver types. The PolaRx5 receiver showed less SNR variation between tracking channels than both Trimble receivers. Our results show the power levels at which adjacent-band interference begins degrading receiver performance and eventually disables tracking. As the demand for spectrum for mobile applications increases, operators of hazard networks may need to consider the impact of RF interference on data quality and continuity. UNAVCO's participation ensures that our high precision GNSS community interests are represented in the future spectrum allocation decisions.
Long Valley Caldera-Mammoth Mountain unrest: The knowns and unknowns
Hill, David P.
2017-01-01
This perspective is based largely on my study of the Long Valley Caldera (California, USA) over the past 40 years. Here, I’ll examine the “knowns” and the “known unknowns” of the complex tectonic–magmatic system of the Long Valley Caldera volcanic complex. I will also offer a few brief thoughts on the “unknown unknowns” of this system.
Echinococcus granulosus in gray wolves and ungulates in Idaho and Montana, USA.
Foreyt, William J; Drew, Mark L; Atkinson, Mark; McCauley, Deborah
2009-10-01
We evaluated the small intestines of 123 gray wolves (Canis lupus) that were collected from Idaho, USA (n=63), and Montana, USA (n=60), between 2006 and 2008 for the tapeworm Echinococcus granulosus. The tapeworm was detected in 39 of 63 wolves (62%) in Idaho, USA, and 38 of 60 wolves (63%) in Montana, USA. The detection of thousands of tapeworms per wolf was a common finding. In Idaho, USA, hydatid cysts, the intermediate form of E. granulosus, were detected in elk (Cervus elaphus), mule deer (Odocoileus hemionus), and a mountain goat (Oreamnos americanus). In Montana, USA, hydatid cysts were detected in elk. To our knowledge, this is the first report of adult E. granulosus in Idaho, USA, or Montana, USA. It is unknown whether the parasite was introduced into Idaho, USA, and southwestern Montana, USA, with the importation of wolves from Alberta, Canada, or British Columbia, Canada, into Yellowstone National Park, Wyoming, USA, and central Idaho, USA, in 1995 and 1996, or whether the parasite has always been present in other carnivore hosts, and wolves became a new definitive host. Based on our results, the parasite is now well established in wolves in these states and is documented in elk, mule deer, and a mountain goat as intermediate hosts.
USDA-ARS?s Scientific Manuscript database
Ambrosiozyma oregonensis sp. nov. (NRRL Y-6106T = CBS 5560, type strain) is described from two strains, one isolated from a mountain stream in Oregon, USA, and a second (NRRL YB-4169) from an unknown substrate from Marion, Illinois, USA. The species forms four hat-shaped ascospores in each deliquesc...
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Select Committee on Indian Affairs.
These papers provide indepth analyses of barriers to and proposals for economic development on Indian reservations. The collection is a follow through to April 29, 1982 hearings of the Select Committee on Indian Affairs of the United States Senate. Alan R. Parker and Charles Trimble survey Indian economic development issues including the federal…
Kobayashi, Scott D; Malachowa, Natalia; Whitney, Adeline R; Braughton, Kevin R; Gardner, Donald J; Long, Dan; Bubeck Wardenburg, Juliane; Schneewind, Olaf; Otto, Michael; Deleo, Frank R
2011-09-15
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are frequently associated with strains harboring genes encoding Panton-Valentine leukocidin (PVL). The role of PVL in the success of the epidemic CA-MRSA strain USA300 remains unknown. Here we developed a skin and soft tissue infection model in rabbits to test the hypothesis that PVL contributes to USA300 pathogenesis and compare it with well-established virulence determinants: alpha-hemolysin (Hla), phenol-soluble modulin-alpha peptides (PSMα), and accessory gene regulator (Agr). The data indicate that Hla, PSMα, and Agr contribute to the pathogenesis of USA300 skin infections in rabbits, whereas a role for PVL could not be detected.
A practitioner's tool for assessing glide crack activity
Hendrikx, Jordy; Peitzsch, Erich H.; Fagre, Daniel B.
2010-01-01
Glide cracks can result in full-depth glide avalanche release. Avalanches from glide cracks are notoriously difficult to forecast, but are a reoccurring problem in a number of different avalanche forecasting programs across a range of snow climates. Despite this, there is no consensus for how to best manage, mitigate, or even observe glide cracks and the potential resultant avalanche activity. It is thought that an increase in the rate of snow gliding occurs prior to full-depth avalanche activity, so frequent measuring of glide crack movement provides an index of instability. Therefore, a comprehensive avalanche program with glide crack avalanche activity, should at the least, undertake some form of direct monitoring of glide crack movement. In this paper we present a simple, cheap and repeatable method to track glide crack activity using a series of stakes, reflectors and a laser rangefinder (LaserTech TruPulse360B) linked to a GPS (Trimble Geo XH). We tested the methodology in April 2010, on a glide crack above the Going to the Sun Road in Glacier National Park, Montana, USA. This study suggests a new method to better track the development and movement of glide cracks. It is hoped that by introducing a workable method to easily record glide crack movement, avalanche forecasters will improve their understanding of when, or if, avalanche activity will ensue. Our initial results suggest that these new observations, when combined with local micrometeorological data will result in improved process understanding and forecasting of these phenomena.
2015-05-01
multiple automated cognitive tests, data management and reporting capabilities, and executive menu. The DANA battery was given on a Trimble NOMAD ...handheld computing device using a stylus for consistency. The NOMAD runs a custom version of the Android Operating System and has a color 3.5 inch... digit pairs are shown below a key, & the participant indicates it matches the one in the key. PRO This test targets decision-making capabilities
Publications - GMC 63 | Alaska Division of Geological & Geophysical Surveys
DGGS GMC 63 Publication Details Title: Extractable organic matter analysis data of Pan American USA publication sales page for more information. Bibliographic Reference Unknown, 1985, Extractable organic matter
Publications - GMC 131 | Alaska Division of Geological & Geophysical
and core from the Chevron USA Inc. Eagle Creek #1 well Authors: Unknown Publication Date: 1989 Inc. Eagle Creek #1 well: Alaska Division of Geological & Geophysical Surveys Geologic Materials
NASA Astrophysics Data System (ADS)
Zimakov, L. G.; Raczka, J.; Barrientos, S. E.
2016-12-01
We will discuss and show the results obtained from an integrated SeismoGeodetic System, model SG160-09, installed in the Chile (Chilean National Network), Italy (University of Naples Network), and California. The SG160-09 provides the user high rate GNSS and accelerometer data, full epoch-by-epoch measurement integrity and the ability to create combined GNSS and accelerometer high-rate (200Hz) displacement time series in real-time. The SG160-09 combines seismic recording with GNSS geodetic measurement in a single compact, ruggedized case. The system includes a low-power, 220-channel GNSS receiver powered by the latest Trimble-precise Maxwell™6 technology and supports tracking GPS, GLONASS and Galileo signals. The receiver incorporates on-board GNSS point positioning using Real-Time Precise Point Positioning (PPP) technology with satellite clock and orbit corrections delivered over IP networks. The seismic recording includes an ANSS Class A, force balance accelerometer with the latest, low power, 24-bit A/D converter, producing high-resolution seismic data. The SG160-09 processor acquires and packetizes both seismic and geodetic data and transmits it to the central station using an advanced, error-correction protocol providing data integrity between the field and the processing center. The SG160-09 has been installed in three seismic stations in different geographic locations with different Trimble global reference stations coverage The hardware includes the SG160-09 system, external Zephyr Geodetic-2 GNSS antenna, both radio and high-speed Internet communication media. Both acceleration and displacement data was transmitted in real-time to the centralized Data Acquisition Centers for real-time data processing. Command/Control of the field station and real-time GNSS position correction are provided via the Pivot platform. Data from the SG160-09 system was used for seismic event characterization along with data from traditional seismic and geodetic stations installed in the network. Our presentation will focus on the key improvements of the network installation with the SG160-09 system, RTX correction accuracy obtained from Trimble Global RTX tracking network, rapid data transmission, and real-time data processing for strong seismic events and aftershock characterization.
A Milestone in Cancer Research and Treatment in India
Tata Memorial Center is celebrating 75 years of leadership service towards cancer control and research in India. In honor of this anniversary, TMC is hosting A Conference of New Ideas in Cancer – Challenging Dogmas on February 26-28th, 2016 as part of its platinum jubilee events. CGH Director, Dr. Ted Trimble, will give a plenary talk: "Thinking Outside the Box in Cancer Research - Perspectives from the US NCI” in the session titled: Future of Cancer Research: US and European perspectives.
Objectification of Public Bus Stop's Pavement Surface Morphology
NASA Astrophysics Data System (ADS)
Decký, Martin; Kováč, Matúš; Mužík, Juraj; Mičechová, Lenka; Ďuriš, Lukáš
2018-06-01
The article deals with the road pavement surface morphology objectification in term of the surface unevenness degradation during the life cycle of bus stop pavements. The article presents the results of long-term rut depth measurements performed during 25 years on selected bus stops which were intended to determine correlation dependences of pavement rut depth on a number of design axles. The article also presents different methods for rut depth measurements including the straightedge test, Profilograph GE, TRIMBLE CX, and dynamic Road Scanner.
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Select Committee on Indian Affairs.
The objective of the August 16, 1978, United States Senate hearing was to determine reorganization plans for the Bureau of Indian Affairs (BIA). The Assistant Secretary of the Interior for Indian Affairs, two Deputy Secretaries, and Mr. Charles Trimble of the United Effort Trust testified before the Select Committee on Indian Affairs. The…
The New Wizard War: Challenges and Opportunities for Electronic Warfare in the Information Age
2007-11-06
Camp: Preparing for Conflict in the Information Age (Santa Monica, CA: RAND Corporation, 1997):175. 17. Jeffrey R . Cares, “An Information Age Combat...60. Stephen Trimble, “US Army Moves Back Into Electronic Attack Mission.” 61. Richard R . Burgess, “Jamming: The Marine Corps Refines Its Vision of...November 7, 2005), http://www.aviationweek.com/aw/generic/story_generic.jsp?channel= awst &id=news/11075p 2.xml (accessed 29 Oct 07). 74. David A
2016-04-01
Program ft foot/feet GPS Global Positioning System HE High Explosive ID Identification IDA Institute for Defense Analysis IMU Inertial Measurement Unit ISO...were replaced with two ski-shaped runners, and a new mount above the array was used to hold the Inertial Measurement Unit (IMU) and Trimble R8 Real...to collect a cued data measurement (Figure 9). The instrument’s pitch, roll , and yaw angles automatically were measured by the IMU. These angles and
DoD Metric Seminar/Workshop (1980) Held in Washington, DC 18-20 November 1980.
1981-04-23
SECTION OF THE FEDERAL REGISTER IN FINAL FORM ON SEPTEMBER 16, 1980. ADDITIONALLY, THE BOARD HAS IN COOPERATION WITH THE DEPARTMENT OF JUSTICE AND THE...TRLMBLE Mr. Trimble was born in Alabama and reared in Virginia. He graduated from the United States Military Academy in 1945 with a Bachelor of Science...BF685A, The Pentagon Washington, DC 20301 202-695-9996 AV 225-9996 119. Wilton McIntosh Bureau of Medicine and Surgery Department of the Navy Washington
Puchalski, Mateusz; Giłka, Wojciech
2017-03-10
Two species of the genus Cladotanytarsus Kieffer, 1921 are described as adult males, both peculiar in having distinctively elongated hypopygial anal points. The male of Cladotanytarsus bilyji Giłka et Puchalski, sp. nov. (Canada, Manitoba; USA, Ohio) is presumed to be a close relative of C. nigrovittatus (Goetghebuer, 1922). Another unknown Cladotanytarsus species (USA, Illinois and Louisiana) keys with the European C. donmcbeani Langton et McBean, 2010. The intraspecific variability of the male C. acornutus Jacobsen et Bilyj, 2007 is also presented on the basis of new records (Canada, Ontario; USA, South Carolina). Cladotanytarsus males with similarly structured elongate anal points are reviewed, including C. tobaquardecimus Kikuchi et Sasa, 1990, considered a junior synonym (syn. nov.) of C. conversus (Johannsen, 1932). As a compilation of this study, a key to the identification of the adult males of 14 Cladotanytarsus species is provided.
Fajardo, Geroncio C.; Posid, Joseph; Papagiotas, Stephen; Lowe, Luis
2015-01-01
There have been periodic electronic news media reports of potential bioterrorism-related incidents involving unknown substances (often referred to as “white powder”) since the 2001 intentional dissemination of Bacillus anthracis through the US Postal System. This study reviewed the number of unknown “white powder” incidents reported online by the electronic news media and compared them with unknown “white powder” incidents reported to the US Centers for Disease Control and Prevention (CDC) and the US Federal Bureau of Investigation (FBI) during a two-year period from June 1, 2009 and May 31, 2011. Results identified 297 electronic news media reports, 538 CDC reports, and 384 FBI reports of unknown “white powder.” This study showed different unknown “white powder” incidents captured by each of the three sources. However, the authors could not determine the public health implications of this discordance. PMID:25420771
Using Internet-Based Automated Software to Process GPS Data at Michigan Tech University
NASA Astrophysics Data System (ADS)
Crook, A.; Diehl, J. F.
2003-12-01
The Michigan Tech University GPS monument was made operational in October of 2002. The monument, which consists of a concrete pillar extending approximately 10 feet below the surface and protrudes 5 feet above ground, is located at the Houghton County Memorial Airport (47.171803° N, 88.498361° W). The primary purpose of the monument is to measure the velocity of the North American Plate at this location. A Trimble 4000ssi geodetic receiver with a Trimble Zephyr antenna is used to collect GPS data. The data are sent to a PC where they are processed using Auto-GIPSY, an internet-based GPS processing utility, which makes it possible to process GPS data, via email, without having knowledge of how the software works. Two Perl scripts were written to facilitate automation and to simplify processing of the GPS data even further. Twelve months of GPS data were processed, using Auto-GIPSY, which produced a velocity of -24 +/- 5 mm/yr and -4 +/- 6 mm/yr for the X and Y components respectively with an azimuth of 261° with respect to the ITRF2000. This calculated result compares well with the NNR-NUVEL1A velocity of -17 mm/yr and -1 mm/yr for the X and Y components respectively with an azimuth of 267° . The results from an alternative online processing service, the Scripps Coordinate Update Tool (SCOUT) that uses GAMIT, will also be presented as a comparative method.
Congenital transmission of Neospora caninum in white tailed deer (Odocoileus virginianus)
USDA-ARS?s Scientific Manuscript database
Neosporosis is an important cause of bovine abortion worldwide. Many aspects of transmission of Neospora caninum in nature are unknown. The white-tailed deer (Odocoileus virginianus) is considered one of the most important wildlife reservoirs of N. caninum in the USA. During the hunting seasons of 2...
Spatial probability models of fire in the desert grasslands of the southwestern USA
USDA-ARS?s Scientific Manuscript database
Fire is an important driver of ecological processes in semiarid environments; however, the role of fire in desert grasslands of the Southwestern US is controversial and the regional fire distribution is largely unknown. We characterized the spatial distribution of fire in the desert grassland region...
Lovich, Jeffrey E.
2011-01-01
I observed an adult Desert Tortoise and an adult Red Diamond Rattlesnake (sexes unknown) in a shallow tortoise burrow on 6 January 1997 at a wind energy generation facility near Palm Springs, Riverside Co., California, USA (33.9599°N, 116.6613°W).
The aim of this overall project was to explore the utility of ?‘omics’ approaches in monitoring aquatic environments where complex, often unknown, stressors make chemical-specific risk assessment untenable. This specific component of the effort examined changes in the fathead min...
This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.
Climate, wildfire, and erosion ensemble foretells more sediment in western USA watersheds
Sankey, Joel B.; Kreitler, Jason R.; Hawbaker, Todd; McVay, Jason L.; Miller, Mary Ellen; Mueller, Erich R.; Vaillant, Nicole M.; Lowe, Scott E.; Sankey, Temuulen T.
2017-01-01
The area burned annually by wildfires is expected to increase worldwide due to climate change. Burned areas increase soil erosion rates within watersheds, which can increase sedimentation in downstream rivers and reservoirs. However, which watersheds will be impacted by future wildfires is largely unknown. Using an ensemble of climate, fire, and erosion models, we show that post-fire sedimentation is projected to increase for nearly nine-tenths of watersheds by > 10% and for more than one-third of watersheds by > 100% by the 2041 to 2050 decade in the western USA. The projected increases are statistically significant for more than eight-tenths of the watersheds. In the western USA, many human communities rely on water from rivers and reservoirs that originates in watersheds where sedimentation is projected to increase. Increased sedimentation could negatively impact water supply and quality for some communities, in addition to affecting stream channel stability and aquatic ecosystems.
Association of marital status and colorectal cancer screening participation in the USA.
El-Haddad, B; Dong, F; Kallail, K J; Hines, R B; Ablah, E
2015-05-01
In the USA, for both men and women, colorectal cancer (CRC) ranks third in incidence and second in mortality. Despite evidence that it decreases mortality, CRC screening in the USA remains under-utilized. Some European studies have suggested that marital status affects participation in CRC screening, but the effect of marital status on CRC screening participation in the USA is unknown. In this study, the aim was to compare CRC screening participation rates among married and unmarried couples, separated, widowed, never married and divorced adults living in the USA. This was a retrospective data analysis of the 2010 Behavioural Risk Factor Surveillance System survey. The population studied included 239,300 participants, aged 50-75 years, who completed the 2010 survey. Logistic regression analysis was conducted to assess the association between adherence with CRC screening guidelines and marital status while accounting for survey stratum/weight and covariates. Individuals who were divorced or separated, never married or widowed had decreased odds of adherence with CRC screening guidelines compared with individuals who were married and unmarried couples. In this study, individuals living in the USA who were married and unmarried couples had increased odds of undergoing CRC screening compared to individuals in other marital status groups. Public health interventions are needed to promote CRC screening participation in these other groups. Colorectal Disease © 2015 The Association of Coloproctology of Great Britain and Ireland.
Climate, wildfire, and erosion ensemble foretells more sediment in western USA watersheds
Joel B. Sankey; Jason Kreitler; Todd J. Hawbaker; Jason L. McVay; Mary Ellen Miller; Erich R. Mueller; Nicole M. Vaillant; Scott E. Lowe; Temuulen T. Sankey
2017-01-01
The area burned annually by wildfires is expected to increase worldwide due to climate change. Burned areas increase soil erosion rates within watersheds, which can increase sedimentation in downstream rivers and reservoirs. However, which watersheds will be impacted by future wildfires is largely unknown. Using an ensemble of climate, fire, and erosion models, we show...
USDA-ARS?s Scientific Manuscript database
Recent surveys in southern Florida, USA, Brazil and Argentina, for biological control agents to assist in the control of the invasive Brazilian peppertree, have discovered several previously unknown species of plant mining Lepidoptera of the family Gracillariidae. Morphological descriptions with sum...
Erica A. H. Smithwick; Daniel M. Kashian; Michael G. Ryan; Monica G. Turner
2009-01-01
Long-term, landscape patterns in inorganic nitrogen (N) availability and N stocks following infrequent, stand-replacing fire are unknown but are important for interpreting the effect of disturbances on ecosystem function. Here, we present results from a replicated chronosequence study in the Greater Yellowstone Ecosystem (Wyoming, USA) directed at measuring inorganic N...
Introduction of ponderosa pine and Douglas-fir to Argentina
Gerald E. Rehfeldt; Leonardo A. Gallo
2001-01-01
Patterns of shoot elongation of 2-yr seedlings from native North American populations of ponderosa pine and Douglas-fir were compared to those of Argentine land races originating from unknown provenances. The comparisons were conducted in Moscow, Idaho (USA), and suggested that the ponderosa pine land race was descended from a California provenance at low or middle...
NASA Astrophysics Data System (ADS)
Brevik, E. C.; Heilig, J.; Kempenich, J.; Doolittle, J.; Ulmer, M.
2012-04-01
Sodium-affected soils (SAS) cover over 4 million hectares in the Northern Great Plains of the United States. Improving the classification, interpretation, and mapping of SAS is a major goal of the United States Department of Agriculture-Natural Resource Conservation Service (USDA-NRCS) as Northern Great Plains soil surveys are updated. Apparent electrical conductivity (ECa) as measured with ground conductivity meters has shown promise for mapping SAS, however, this use of this geophysical tool needs additional evaluation. This study used an EM-38 MK2-2 meter (Geonics Limited, Mississauga, Ontario), a Trimble AgGPS 114 L-band DGPS (Trimble, Sunnyvale, CA) and the RTmap38MK2 program (Geomar Software, Inc., Mississauga, Ontario) on an Allegro CX field computer (Juniper Systems, North Logan, UT) to collect, observe, and interpret ECa data in the field. The ECa map generated on-site was then used to guide collection of soil samples for soil characterization and to evaluate the influence of soil properties in SAS on ECa as measured with the EM-38MK2-2. Stochastic models contained in the ESAP software package were used to estimate the SAR and salinity levels from the measured ECa data in 30 cm depth intervals to a depth of 90 cm and for the bulk soil (0 to 90 cm). This technique showed promise, with meaningful spatial patterns apparent in the ECa data. However, many of the stochastic models used for salinity and SAR for individual depth intervals and for the bulk soil had low R-squared values. At both sites, significant variability in soil clay and water contents along with a small number of soil samples taken to calibrate the ECa values to soil properties likely contributed to these low R-squared values.
100 years of elementary particles [Beam Line, vol. 27, issue 1, Spring 1997
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pais, Abraham; Weinberg, Steven; Quigg, Chris
1997-04-01
This issue of Beam Line commemorates the 100th anniversary of the April 30, 1897 report of the discovery of the electron by J.J. Thomson and the ensuing discovery of other subatomic particles. In the first three articles, theorists Abraham Pais, Steven Weinberg, and Chris Quigg provide their perspectives on the discoveries of elementary particles as well as the implications and future directions resulting from these discoveries. In the following three articles, Michael Riordan, Wolfgang Panofsky, and Virginia Trimble apply our knowledge about elementary particles to high-energy research, electronics technology, and understanding the origin and evolution of our Universe.
100 years of Elementary Particles [Beam Line, vol. 27, issue 1, Spring 1997
DOE R&D Accomplishments Database
Pais, Abraham; Weinberg, Steven; Quigg, Chris; Riordan, Michael; Panofsky, Wolfgang K. H.; Trimble, Virginia
1997-04-01
This issue of Beam Line commemorates the 100th anniversary of the April 30, 1897 report of the discovery of the electron by J.J. Thomson and the ensuing discovery of other subatomic particles. In the first three articles, theorists Abraham Pais, Steven Weinberg, and Chris Quigg provide their perspectives on the discoveries of elementary particles as well as the implications and future directions resulting from these discoveries. In the following three articles, Michael Riordan, Wolfgang Panofsky, and Virginia Trimble apply our knowledge about elementary particles to high-energy research, electronics technology, and understanding the origin and evolution of our Universe.
The CEO's role in business model reinvention.
Govindarajan, Vijay; Trimble, Chris
2011-01-01
Fending off new competitors is a perennial struggle for established companies. Govindarajan and Trimble, of Dartmouth's Tuck School of Business, explain why: Many corporations become too comfortable with their existing business models and neglect the necessary work of radically reinventing them. The authors map out an alternative in their "three boxes" framework. They argue that while a CEO manages the present (box 1), he or she must also selectively forget the past (box 2) in order to create the future (box 3). Infosys chairman N.R. Narayana Murthy mastered the three boxes to reinvigorate his company and greatly increased its changes of enduring for generations.
First Apollo 11 sample return containers arrive at Ellington AFB
NASA Technical Reports Server (NTRS)
1969-01-01
The first Apollo 11 sample return container, containing lunar surface material, arrives at Ellington Air Force Base by air from the Pacific recovery area. Happily posing for photographs with the rock box are (left to right) George M. Low, Manager, Apollo Spacecraft Program, Manned Spacecraft Center (MSC); U.S. Air Force Lt. Gen. Samuel C. Phillips, Apollo Program Director, Office of Manned Space Flight, NASA HQ.; George S. Trimble, MSC Deputy Director (almost obscured); Eugene G. Edmonds, MSC Photographic Technology Laboratory; RIchard S. Johnston (in back), Special Assistant to the MSC Director; Dr. Thomas O. Paine, NASA Administrator; and Dr. Robert R. Gilruth, MSC Director.
The first dozen years of the history of ITEP Theoretical Physics Laboratory
NASA Astrophysics Data System (ADS)
Ioffe, B. L.
2013-01-01
The theoretical investigations at ITEP in the years 1945 - 1958 are reviewed. There are exposed the most important theoretical results, obtained in the following branches of physics: (1) the theory of nuclear reactors on thermal neutrons; (2) the hydrogen bomb project ("Tube" in USSR and "Classical Super" in USA); (3) radiation theory; (4) low temperature physics; (5) quantum electrodynamics and quantum field theories; (6) parity violation in weak interactions, the theory of β-decay and other weak processes; (7) strong interaction and nuclear physics. To the review are added the English translations of a few papers, originally published in Russian, but unknown (or almost unknown) to Western readers.
Alison C. Dibble; Robert H. White; Patricia K. Lebow
2007-01-01
In the north-eastern United States, invasive plants alter forest fuels, but their combustion characteristics are largely unknown. We assessed unground samples of foliage and twigs in the cone calorimeter for 21 non-invasive, native species, paired with 21 invasive species (18 non-native). Variables included sustained ignition, peak heat release rate, total heat release...
Helicobacter pylori Clarithromycin Resistance and Treatment Failure Are Common in the USA.
Park, Jason Y; Dunbar, Kerry B; Mitui, Midori; Arnold, Christina A; Lam-Himlin, Dora M; Valasek, Mark A; Thung, Irene; Okwara, Chinemerem; Coss, Elizabeth; Cryer, Byron; Doern, Christopher D
2016-08-01
Helicobacter pylori antibiotic resistance leads to frequent treatment failure. However, the current US prevalence of H. pylori clarithromycin resistance and treatment failure is unknown. To determine the prevalence of clarithromycin-resistant H. pylori and its impact on treatment failure in the USA. A multicenter, retrospective, cohort study for clarithromycin-resistant H. pylori was conducted over four academic medical centers in different geographic regions of the USA. Gastric biopsy material, residual from standard clinical pathologic examination, was examined for clarithromycin resistance by DNA sequencing of H. pylori 23S rRNA. One hundred and twenty-four cases of H. pylori gastritis were examined from medical centers in four different geographic regions of the USA. The overall prevalence of clarithromycin resistance was 32.3 % (range 23.1-45.8 %). There was no significant difference in the prevalence of clarithromycin resistance by study site, gender, age, or race/ethnicity. In a subset of 67 patients that had clinical follow-up data, the overall prevalence of clarithromycin resistance was 31.3 %. There was a 2.9-fold increase (p = 0.002) in treatment failure for cases with clarithromycin resistance (57.1 %) compared to wildtype H. pylori (19.6 %). H. pylori clarithromycin resistance in the USA exceeds the estimated 20 % prevalence compatible with successful empiric antibiotic therapy. This resistance resulted in a significant rate of treatment failure in all sites surveyed. Empiric therapy in the USA should be used with caution until there is better regional or local determination of H. pylori antibiotic resistance.
Transmission of multidrug-resistant tuberculosis in the USA: a cross-sectional study.
Moonan, Patrick K; Teeter, Larry D; Salcedo, Katya; Ghosh, Smita; Ahuja, Shama D; Flood, Jennifer; Graviss, Edward A
2013-09-01
Multidrug-resistant (MDR) tuberculosis is a potential threat to tuberculosis elimination, but the extent of MDR tuberculosis disease in the USA that is attributable to transmission within the country is unknown. We assessed transmission of MDR tuberculosis and potential contributing factors in the USA. In a cross-sectional study, clinical, demographic, epidemiological, and Mycobacterium tuberculosis genotype data were obtained during routine surveillance of all verified cases of MDR tuberculosis reported from eight states in the USA (California from Jan 1, 2007, to Dec 31, 2009; Texas from Jan 1, 2007, to March 31, 2009; and the states of Colorado, Maryland, Massachusetts, New York, Tennessee, and Washington from Jan 1, 2007 to Dec 31, 2008). In-depth interviews and health-record abstraction were done for all who consented to ascertain potential interpersonal connections. 168 cases of MDR tuberculosis were reported in the eight states during our study period. 92 individuals (55%) consented to in-depth interview. 20 (22%) of these individuals developed MDR tuberculosis as a result of transmission in the USA; a source case was identified for eight of them (9%). 20 individuals (22%) had imported active tuberculosis (ie, culture-confirmed disease within 3 months of entry into the USA). 38 (41%) were deemed to have reactivation of disease, of whom 14 (15%) had a known previous episode of tuberculosis outside the USA. Five individuals (5%) had documented treatment of a previous episode in the USA, and so were deemed to have relapsed. For nine cases (10%), insufficient evidence was available to definitively classify reason for presentation. About a fifth of cases of MDR tuberculosis in the USA can be linked to transmission within the country. Many individuals acquire MDR tuberculosis before entry into the USA. MDR tuberculosis needs to be diagnosed rapidly to reduce potential infectious periods, and clinicians should consider latent tuberculosis infection treatment-tailored to the results of drug susceptibility testing of the putative source case-for exposed individuals. Centers for Disease Control and Prevention. Copyright © 2013 Elsevier Ltd. All rights reserved.
GIS, GPS, political history, and geo-demography of the Aramamisi Yanomamo expansion
NASA Technical Reports Server (NTRS)
Chagnon, Napoleon A.
1991-01-01
This year a joint US-Venezuelan research project was initiated to locate, identify, and begin long term research on the ecology of the Siapa Basin and the cultural adaptations of Yanomamo communities to this habit, a poorly mapped region of southern Venezuela. During two separate field trips, representing over 500 hours of flying time, local informants were asked to guide a helicopter to villages and other areas of anthropological interest. The location of each place was established with a GPS instrument. Both the Trimble Navigation TransPak and Magellan Nav 1000 Pro were used on these trips. A brief summary of the results and preliminary comparisons of both instruments will be presented.
Inflight - Apollo XI (Mission Control Center [MCC]) - MSC
1969-07-24
S69-40302 (24 July 1969) --- A group of NASA and Manned Spacecraft Center (MSC) officials join in with the flight controllers in the Mission Operations Control Room (MOCR) in the Mission Control Center (MCC), Building 30, in celebrating the successful conclusion of the Apollo 11 lunar landing mission. From left foreground are Dr. Maxime A. Faget, MSC Director of Engineering and Development; George S. Trimble, MSC Deputy Director; Dr. Christopher C. Kraft Jr., MSC Director of Flight Operations; Julian Scheer (in back), Assistant Administrator, Office of Public Affairs, NASA Headquarters; George M. Low, Manager, Apollo Spacecraft Program, MSC; Dr. Robert R. Gilruth, MSC Director; and Charles W. Mathews, Deputy Associate Administrator, Office of Manned Space Flight, NASA Headquarters.
Belisle, Jeffery G; Wenke, Joseph C; Krueger, Chad A
2013-08-01
The purpose of this study was to identify the differences seen between military occupation services (MOS) in terms of amputation patterns, subsequent disabling conditions, and their ability to return to duty. A retrospective study of major extremity amputations sustained by US service members between October 1, 2001, and July 30, 2011, was performed. Data obtained from the amputation database, Joint Trauma Theater Database, and the Physical Evaluation Board Liaison Office included demographics, amputation location(s), Injury Severity Scores (ISSs), disabling conditions, disability ratings, and disposition status. There were 1,221 major extremity amputees identified during the specified time frame, of which 899 had data regarding disabling conditions, ratings, and disposition. All service branches were represented. Personnel from the US Army (USA) Infantry were significantly (p < 0.0001) more likely to sustain an amputation than other MOS. The USA Infantry, the US Marine Corps Infantry and the USA Armor represented the top three specialties and accounted for more than 57% of all amputees. Approximately 89% of all service members did not return to duty, and the mean combined for all amputees was 76. USA Special Forces (USA SF) operators were significantly more likely to return to duty (p = 0.0022) and be found fit for duty (p = 0.0015) than all other MOS despite having a mean ISS (20) that was no different from those of other service members. No USA SF personnel were found to have posttraumatic stress disorder as a disabling condition. All amputees, regardless of MOS, are not likely to return to active duty and especially unlikely to be found fit for duty, except for members of the USA SF. The reason(s) for the increased return to duty for USA SF personnel remains unknown but a lack of posttraumatic stress disorder may be a contributing factor.
Effects of timber harvesting on birds in the Black Hills of South Dakota and Wyoming, USA
Brian L. Dykstra; Mark A. Rumble; Lester D. Flake
1997-01-01
Timber harvest alters structural characteristics in ponderosa pine forests. In the Black Hills, harvested stands with 40-70% overstory canopy cover are managed as sapling/pole (3.0 - 22.9 cm dbh) or mature (> 22.9 cm dbh) stands. Changing the forest structure to two size classes has unknown effects on bird communities in this region. We counted birds in 20 harvested...
2013-07-01
USA (2013); 2) Many environmental yeast are extremely radiation-resistant, accumulate nitrogenous Mn2+-Pi complexes, and highly resistant to...5 important in aerobic environments . Numerous organisms which accumulate “compatible solutes” fit this model, including representative archaea...cyanobacteria, lichens, alpine yeast, and tardigrades. 4.3 Knowns and Unknowns of Deinococcus Mn2+ Complexes It is worth reminding the reader
Candelora, Kristen L; Spalding, Marilyn G; Sellers, Holly S
2010-07-01
Captive-reared Whooping Cranes (Grus americana) released into Florida for the resident reintroduction project experienced unusually high mortality and morbidity during the 1997-98 and 2001-02 release seasons. Exposure to infectious bursal disease virus (IBDV) serotype 2 as evidenced by seroconversion was suspected to be the factor that precipitated these mortality events. Very little is known about the incidence of IBD in wild bird populations. Before this study, natural exposure had not been documented in wild birds of North America having no contact with captive-reared cranes, and the prevalence and transmission mechanisms of the virus in wild birds were unknown. Sentinel chickens (Gallus gallus) monitored on two Whooping Crane release sites in central Florida, USA, during the 2003-04 and 2004-05 release seasons seroconverted, demonstrating natural exposure to IBDV serotype 2. Blood samples collected from Wild Turkeys (Meleagris gallopavo) and Sandhill Cranes (Grus canadensis) in eight of 21 counties in Florida, USA, and one of two counties in southern Georgia, USA, were antibody-positive for IBDV serotype 2, indicating that exposure from wild birds sharing habitat with Whooping Cranes is possible. The presence of this virus in wild birds in these areas is a concern for the resident flock of Whooping Cranes because they nest and raise their chicks in Florida, USA. However, passively transferred antibodies may protect them at this otherwise vulnerable period in their lives.
Nationwide epidemiological survey of childhood IgA vasculitis associated hospitalization in the USA.
Okubo, Yusuke; Nochioka, Kotaro; Sakakibara, Hiroshi; Hataya, Hiroshi; Terakawa, Toshiro; Testa, Marcia; Sundel, Robert P
2016-11-01
At the national level, IgA vasculitis-related hospitalizations among children in the USA are scarce. Furthermore, nationwide epidemiology and hospital course of children with IgA vasculitis have not been fully described in the USA, and disparities by race/ethnicity remain unknown. Hospital discharge records of patients aged 19 years or younger were obtained from the 2003, 2006, 2009, and 2012 Kids' Inpatient Database, and they were weighted to estimate the annual hospitalization rates with respect to age, gender, and race/ethnicity in the USA. Annual hospitalization rates were calculated using weighted case estimates and US census data. Negative binomial regression was used to ascertain the factors associated with length of hospital stay. Total annual hospitalization rates showed a significant decreasing trend, ranging from 2.45 per 100,000 children in 2003 to 1.89 per 100,000 children in 2012 (p < 0.001). The peak ages of the hospitalized children with IgA vasculitis were 2 and 7 years, and male-to-female ratios were 1.38-1.44. Factors associated with length of hospital stay were patients' ages (10-14 and 15-19 years), race/ethnicity (Hispanic, Asian, and Pacific Islander), comorbid electrolyte abnormality, GI hemorrhage, intussusception, renal symptoms, and GI symptoms. The annual hospitalization rates for IgA vasculitis are declining in the USA across multiple age groups. GI and renal manifestations are associated with increased length of hospital stay.
Magnuson, Matthew L; Satzger, R Duane; Alcaraz, Armando; Brewer, Jason; Fetterolf, Dean; Harper, Martin; Hrynchuk, Ronald; McNally, Mary F; Montgomery, Madeline; Nottingham, Eric; Peterson, James; Rickenbach, Michael; Seidel, Jimmy L; Wolnik, Karen
2012-05-01
Since the early 1990s, the FBI Laboratory has sponsored Scientific Working Groups to improve discipline practices and build consensus among the forensic community. The Scientific Working Group on the Forensic Analysis of Chemical, Biological, Radiological and Nuclear Terrorism developed guidance, contained in this document, on issues forensic laboratories encounter when accepting and analyzing unknown samples associated with chemical terrorism, including laboratory capabilities and analytical testing plans. In the context of forensic analysis of chemical terrorism, this guidance defines an unknown sample and addresses what constitutes definitive and tentative identification. Laboratory safety, reporting issues, and postreporting considerations are also discussed. Utilization of these guidelines, as part of planning for forensic analysis related to a chemical terrorism incident, may help avoid unfortunate consequences not only to the public but also to the laboratory personnel. 2011 American Academy of Forensic Sciences. Published 2011. This article is a U.S. Government work and is in the public domain in the U.S.A.
Post-metamorphic fluid infiltration into granulites from the Adirondack Mountains, USA
NASA Technical Reports Server (NTRS)
Morrison, J.; Valley, John W.
1988-01-01
Post-metamorphic effects in the anorthosites of the Adirondacks, New York were described. Calcite-chlorite-sericite assemblages occur as veins, in disseminated form and as clots, and document retrograde fluid infiltration. These features are associated with late-state CO2-rich fluid inclusions. Stable isotope analyses of calcites indicates that the retrograde fluids interacted with meta-igneous and supracrustal lithologies, but the precise timing of the retrogression is as yet unknown.
Dikken, Jeroen; Hoogerduijn, Jita G; Klaassen, Sharon; Lagerwey, Mary D; Shortridge-Baggett, Lillie; Schuurmans, Marieke J
2017-08-01
The Knowledge about Older Patients-Quiz (KOP-Q) is designed as a unidimensional scale measuring knowledge of hospital nurses about older patients. Furthermore, the KOP-Q measures a second unidimensional construct, certainty of hospital nurses about their knowledge. The KOP-Q is developed and validated in the Netherlands. Whether the KOP-Q can be used in other countries is unknown given the cultural and language differences. Investigate the level of measurement invariance of the KOP-Q between the Netherlands and United States of America (USA). A multicenter international cross-sectional design. Four general hospitals in the Netherlands and four general hospitals in the USA. Nurses from the Netherlands (n=201) and the USA (n=130) were invited to participate by email from the ward manager, distributing flyers and present messages on the online hospital communication boards. Questions of the KOP-Q were completed online. The level of measurement invariance (configural, metric or scalar invariance) across countries was tested by running increasingly constrained structural equation models, and testing whether these models fitted the data. Both the knowledge and certainty construct of the KOP-Q proved unidimensional in the Netherlands and USA sample. Test results of the measurement invariance across the Netherlands and USA indicated a stable, partial scalar invariance (15 items full scalar invariance) for the knowledge items and full scalar invariance for the certainty items. The KOP-Q shows to function uniformly across both language groups and can therefore be used to assess nurses' knowledge and their certainty about this knowledge which can be important for educational and/or quality improvement programs in the USA. Furthermore, the KOP-Q is suitable to make comparisons between the Netherlands and the USA using latent variable models. Before the KOP-Q can be used in other countries, cross-cultural tests should again be performed. Copyright © 2017 Elsevier Ltd. All rights reserved.
García-Ruiz, Adriana; Ruiz-López, Felipe de J.; Van Tassell, Curtis P.; Montaldo, Hugo H.; Huson, Heather J.
2015-01-01
The Mexican Holstein (HO) industry has imported Canadian and US (CAN + USA) HO germplasm for use in two different production systems, the conventional (Conv) and the low income (Lowi) system. The objective of this work was to study the genetic composition and differentiation of the Mexican HO cattle, considering the production system in which they perform and their relationship with the Canadian and US HO populations. The analysis included information from 149, 303, and 173 unrelated or with unknown pedigree HO animals from the Conv, Lowi, and CAN + USA populations, respectively. Canadian and US Jersey (JE) and Brown Swiss (BS) genotypes (162 and 86, respectively) were used to determine if Mexican HOs were hybridized with either of these breeds. After quality control filtering, a total of 6,617 out of 6,836 single nucleotide polymorphism markers were used. To describe the genetic diversity across the populations, principal component (PC), admixture composition, and linkage disequilibrium (LD; r2) analyses were performed. Through the PC analysis, HO × JE and HO × BS crossbreeding was detected in the Lowi system. The Conv system appeared to be in between Lowi and CAN + USA populations. Admixture analysis differentiated between the genetic composition of the Conv and Lowi systems, and five ancestry groups associated to sire’s country of origin were identified. The minimum distance between markers to estimate a useful LD was found to be 54.5 kb for the Mexican HO populations. At this average distance, the persistence of phase across autosomes of Conv and Lowi systems was 0.94, for Conv and CAN + USA was 0.92 and for the Lowi and CAN + USA was 0.91. Results supported the flow of germplasm among populations being Conv a source for Lowi, and dependent on migration from CAN + USA. Mexican HO cattle in Conv and Lowi populations share common ancestry with CAN + USA but have different genetic signatures. PMID:25709615
García-Ruiz, Adriana; Ruiz-López, Felipe de J; Van Tassell, Curtis P; Montaldo, Hugo H; Huson, Heather J
2015-01-01
The Mexican Holstein (HO) industry has imported Canadian and US (CAN + USA) HO germplasm for use in two different production systems, the conventional (Conv) and the low income (Lowi) system. The objective of this work was to study the genetic composition and differentiation of the Mexican HO cattle, considering the production system in which they perform and their relationship with the Canadian and US HO populations. The analysis included information from 149, 303, and 173 unrelated or with unknown pedigree HO animals from the Conv, Lowi, and CAN + USA populations, respectively. Canadian and US Jersey (JE) and Brown Swiss (BS) genotypes (162 and 86, respectively) were used to determine if Mexican HOs were hybridized with either of these breeds. After quality control filtering, a total of 6,617 out of 6,836 single nucleotide polymorphism markers were used. To describe the genetic diversity across the populations, principal component (PC), admixture composition, and linkage disequilibrium (LD; r(2) ) analyses were performed. Through the PC analysis, HO × JE and HO × BS crossbreeding was detected in the Lowi system. The Conv system appeared to be in between Lowi and CAN + USA populations. Admixture analysis differentiated between the genetic composition of the Conv and Lowi systems, and five ancestry groups associated to sire's country of origin were identified. The minimum distance between markers to estimate a useful LD was found to be 54.5 kb for the Mexican HO populations. At this average distance, the persistence of phase across autosomes of Conv and Lowi systems was 0.94, for Conv and CAN + USA was 0.92 and for the Lowi and CAN + USA was 0.91. Results supported the flow of germplasm among populations being Conv a source for Lowi, and dependent on migration from CAN + USA. Mexican HO cattle in Conv and Lowi populations share common ancestry with CAN + USA but have different genetic signatures.
Osteopilus septentrionalis (Cuban treefrog)
Glorioso, Brad M.; Steece, Aaron; Lemann, Zachary K.; Lazare, Remy; Beck, James W.
2016-01-01
USA: LOUISIANA: St. Tammany Parish: on private property on Allen Road in Slidell (ca. 30.262°N, 89.741°W; WGS 84). 2 April 2013. Aaron Steece. Verified by Hardin Waddle. Florida Museum of Natural History (UF 177727, photo voucher). New parish record. This adult was found ca. 2 m high on a branch at the edge of a wooded area behind a house. It was photographed and released, as the species identity and significance was unknown. The origin of this individual is unknown. The homeowner stated that he bought nursery plants often, but checked them thoroughly as he put them indoors. Since this initial finding, the homeowner learned more about Cuban Treefrogs and searched for them on many occasions at this location for two years, but detected no additional Cuban Treefrogs.
Creating 3D models of historical buildings using geospatial data
NASA Astrophysics Data System (ADS)
Alionescu, Adrian; Bǎlǎ, Alina Corina; Brebu, Floarea Maria; Moscovici, Anca-Maria
2017-07-01
Recently, a lot of interest has been shown to understand a real world object by acquiring its 3D images of using laser scanning technology and panoramic images. A realistic impression of geometric 3D data can be generated by draping real colour textures simultaneously captured by a colour camera images. In this context, a new concept of geospatial data acquisition has rapidly revolutionized the method of determining the spatial position of objects, which is based on panoramic images. This article describes an approach that comprises inusing terrestrial laser scanning and panoramic images captured with Trimble V10 Imaging Rover technology to enlarge the details and realism of the geospatial data set, in order to obtain 3D urban plans and virtual reality applications.
Sandfort, Theo; Anyamele, C; Dolezal, C
2017-06-01
We examined correlates of sexual risk among gay and bisexual men, who recently migrated from western and eastern African countries to the USA and lived in New York City and who are HIV negative or of unknown status. These men migrate from countries where same-sex sexuality is socially rejected and mostly illegal contributing to the motivation to migrate. Their background might predispose these men to engagement in sexual risk practices, while they are not specifically addressed in HIV prevention programming. Participants (N = 62) reported in face-to-face interviews on pre- and postmigration experiences, psychosocial determinants of sexual risk, and current sexual practices. Operationalization of sexual risk was based on the number of men with whom they had condomless receptive and/or insertive anal sex. Over a third of the men reported always having used condoms in the past year; among the other men, sexual risk varied. Multivariate analyses showed that sexual risk was lower among men with a stronger motivation to avoid HIV infection and higher among men who currently engaged in transactional sex. Further analyses indicated that housing instability was independently associated with reduced motivation to avoid HIV infection and with engagement in transactional sex in the USA. In recent western and eastern African gay and bisexual immigrants to the USA, structural factors, including housing instability, are strongly associated with sexual risk.
Isolation and molecular characterization of a novel picornavirus from baitfish in the USA
Phelps, Nicholas B.D.; Mor, Sunil K.; Armien, Anibal G.; Batts, William N.; Goodwin, Andrew E.; Hopper, Lacey; McCann, Rebekah; Ng, Terry Fei Fan; Puzach, Corey; Waltzek, Thomas B.; Delwart, Eric; Winton, James; Goyal, Sagar M.
2014-01-01
During both regulatory and routine surveillance sampling of baitfish from the states of Illinois, Minnesota, Montana, and Wisconsin, USA, isolates (n = 20) of a previously unknown picornavirus were obtained from kidney/spleen or entire viscera of fathead minnows (Pimephales promelas) and brassy minnows (Hybognathus hankinsoni). Following the appearance of a diffuse cytopathic effect, examination of cell culture supernatant by negative contrast electron microscopy revealed the presence of small, round virus particles (∼30–32 nm), with picornavirus-like morphology. Amplification and sequence analysis of viral RNA identified the agent as a novel member of the Picornaviridae family, tentatively named fathead minnow picornavirus (FHMPV). The full FHMPV genome consisted of 7834 nucleotides. Phylogenetic analysis based on 491 amino acid residues of the 3D gene showed 98.6% to 100% identity among the 20 isolates of FHMPV compared in this study while only 49.5% identity with its nearest neighbor, the bluegill picornavirus (BGPV) isolated from bluegill (Lepomis macrochirus). Based on complete polyprotein analysis, the FHMPV shared 58% (P1), 33% (P2) and 43% (P3) amino acid identities with BGPV and shared less than 40% amino acid identity with all other picornaviruses. Hence, we propose the creation of a new genus (Piscevirus) within the Picornaviridae family. The impact of FHMPV on the health of fish populations is unknown at present.
Environmental contaminants in Texas, USA, wetland reptiles: Evaluation using blood samples
Clark, D.R.; Bickham, J.W.; Baker, D.L.; Cowman, D.F.
2000-01-01
Four species of reptiles (diamondback water snake [Nerodia rhombifer], blotched water snake [N. erythrogaster], cottonmouth [Agkistrodon piscivorus], and red-eared slider [Trachemys scripta]) were collected at two contaminated and three reference sites in Texas, USA. Old River Slough has received intensive applications of agricultural chemicals since the 1950s. Municipal Lake received industrial arsenic wastes continuously from 1940 to 1993. Blood samples were analyzed for organochlorines, potentially toxic elements, genetic damage, and plasma cholinesterase (ChE). Dichlorodiphenyldichloroethylene (DDE) concentrations reached as high as 3.0 ppm (wet weight) in whole blood of a diamondback water snake at Old River Slough, a level probably roughly equivalent to the maximum concentration found in plasma of peregrine falcons (Falco peregrinus) in 1978 to 1979 when DDE peaked in this sensitive species. Possible impacts on diamondback water snakes are unknown, but at least one diamondback water snake was gravid when captured, indicating active reproduction. Arsenic was not found in red-eared sliders (only species sampled) from Municipal Lake. Red-eared sliders of both sexes at Old River Slough showed declining levels of ChE with increasing mass, suggesting a life-long decrease of ChE levels. Possible negative population consequences are unknown, but no evidence was found in body condition (mass relative to carapace length) that red-eared sliders at either contaminated site were harmed.
Random forests for classification in ecology
Cutler, D.R.; Edwards, T.C.; Beard, K.H.; Cutler, A.; Hess, K.T.; Gibson, J.; Lawler, J.J.
2007-01-01
Classification procedures are some of the most widely used statistical methods in ecology. Random forests (RF) is a new and powerful statistical classifier that is well established in other disciplines but is relatively unknown in ecology. Advantages of RF compared to other statistical classifiers include (1) very high classification accuracy; (2) a novel method of determining variable importance; (3) ability to model complex interactions among predictor variables; (4) flexibility to perform several types of statistical data analysis, including regression, classification, survival analysis, and unsupervised learning; and (5) an algorithm for imputing missing values. We compared the accuracies of RF and four other commonly used statistical classifiers using data on invasive plant species presence in Lava Beds National Monument, California, USA, rare lichen species presence in the Pacific Northwest, USA, and nest sites for cavity nesting birds in the Uinta Mountains, Utah, USA. We observed high classification accuracy in all applications as measured by cross-validation and, in the case of the lichen data, by independent test data, when comparing RF to other common classification methods. We also observed that the variables that RF identified as most important for classifying invasive plant species coincided with expectations based on the literature. ?? 2007 by the Ecological Society of America.
Meyers, T.R.; Short, S.; Lipson, K.; Batts, W.N.; Winton, J.R.; Wilcock, J.; Brown, E.
1994-01-01
Only one-third of the Pacific hernng Clupea harengus pallasi expected to spawn in Prince William Sound (PWS), Alaska, USA, in sprlng 1993 were observed. Of these herring, 15 to 43 '% had external ulcers or subdermal hemorrhages of the skln and fins. A rhabdovirus identified as the North American strain of viral hemorrhagic septicemia virus (VHSV) was isolated from affected herring and 1 Pacific cod Gadus macrocephalus with skin lesions from PWS, and from herring with similar lesions collected near Kodiak Island. No other pathogens were detected in the herring examined. Although VHSV may have been responsible for the skin lesions, there was no confirmed mass herring mortality observed in PWS; hence the actual cause of the reduced herring numbers is still unknown. The same strain of VHSV was subsequently isolated from captive juvenile herring collected from Auke Bay, Alaska, near Juneau, from herring in British Columbia, Canada, and from Puget Sound, Washington, USA. These findings suggest the virus is an opportunistic pathogen that is widely indigenous to Pacific herring populations in the Pacific Northwest and that herring are a significant marine reservoir for North American VHSV.
Report of the International Ice Patrol in the North Atlantic. 1986 Season Bulletin Number 72
1986-01-01
business transac-tions from the season. Flight The Intemnational Ice Patrol Month Sooe these nhos requested that all ships transiting -Month Sorties hours...GERMANY 1 EASTERN SHELL UNKNOWN 1 EASTERN UNICORN PANAMA 1 1 ESPANA 1 FEDERAL REPUBLIC OF GERMANY 1 EUROPE BELGIUM 5 EVA FRANCE 1 1 EVERGREEN USA 15 1...when flown at 8000 ft similar pattern, but a winch failure computed using an algorithm (2438 m), maps a 50 km wide after 28 CTD stations resulted in
Lonner, Walter J; Draguns, Juris G
2018-01-01
Presents an obituary for Paul B. Pedersen, who passed away on January 11, 2017, in a Minnetonka, Minnesota hospital. In 1973 Pedersen convened a pathfinding APA (Division 9) symposium in Montreal that resulted in the publication in 1976 of Counseling Across Cultures (Pedersen, Lonner, and Draguns, Eds.). The first book of its kind, it became the "Granddaddy" of all subsequent books in that area. The seventh edition, published in 2016 (with Trimble and Scharron-del Rio, co-eds), benefitted from his steadfast encouragement, but his deteriorating health prevented a more active role. His epitaph may well be one of his wisest and oft-quoted sayings: "All interviewing and counseling is multicultural. Each client comes to the session embodying multiple voices from the past." (PsycINFO Database Record (c) 2018 APA, all rights reserved).
Implications of adolescents' acculturation strategies for personal and collective self-esteem.
Giang, Michael T; Wittig, Michele A
2006-10-01
Berry, Trimble, and Olmedo's (1986) acculturation model was used to investigate the relationship among adolescents' acculturation strategies, personal self-esteem, and collective self-esteem. Using data from 427 high school students, factor analysis results distinguished Collective Self-esteem Scale constructs (Luhtanen & Crocker, 1992) from both ethnic identity and outgroup orientation subscales of the Multigroup Ethnic Identity Measure (Phinney, 1992). Subsequent results showed that: 1) both acculturation dimensions were correlated with personal and collective self-esteems, 2) integrationists shared similar levels of personal and collective self-esteems with assimilationists and/or separationists, and 3) marginalizationists generally had the lowest levels of personal and collective self-esteems. Implications are drawn for understanding acculturation among adolescents and for the utility of group-level measures of self-esteem. (c) 2006 APA, all rights reserved.
Barriers to the free diffusion of proteins and lipids in the plasma membrane.
Trimble, William S; Grinstein, Sergio
2015-02-02
Biological membranes segregate into specialized functional domains of distinct composition, which can persist for the entire life of the cell. How separation of their lipid and (glyco)protein components is generated and maintained is not well understood, but the existence of diffusional barriers has been proposed. Remarkably, the physical nature of such barriers and the manner whereby they impede the free diffusion of molecules in the plane of the membrane has rarely been studied in depth. Moreover, alternative mechanisms capable of generating membrane inhomogeneity are often disregarded. Here we describe prototypical biological systems where membrane segregation has been amply documented and discuss the role of diffusional barriers and other processes in the generation and maintenance of their structural and functional compartmentalization. © 2015 Trimble and Grinstein.
Geodetic antenna calibration test in the Antarctic environment
Grejner-Brzezinska, A.; Vazquez, E.; Hothem, L.
2006-01-01
TransAntarctic Mountain DEFormation (TAMDEF) Monitoring Network is the NSF-sponsored OSU and USGS project, aimed at measuring crustal motion in the Transantarctic Mountains of Victoria Land using GPS carrier phase measurements. Station monumentation, antenna mounts, antenna types, and data processing strategies were optimized to achieve mm-level estimates for the rates of motion. These data contributes also to regional Antarctic frame definition. Significant amount of data collected over several years allow the investigation of unique aspects of GPS geodesy in Antarctica, to determine how the error spectrum compares to the mid-latitude regions, and to identify the optimum measurement and data processing schemes for Antarctic conditions, in order to test the predicted rates of motion (mm-level w.r.t. time). The data collection for the TAMDEF project was initiated in 1996. The primary antenna used has been the Ashtech L1/L2 Dorne Margolin (D/M) choke ring. A few occupations involved the use of a Trimble D/M choke ring. The data were processed using the antenna calibration data available from the National Geodetic Survey (NGS). The recent developments in new antenna designs that are lighter in weight and lower in cost are being considered as a possible alternative to the bulkier and more expensive D/M choke ring design. In November 2003, in situ testing of three alternative models of L1/L2 antennas was conducted at a site located in the vicinity of McMurdo Station, Antarctica (S77.87, E166.56). The antenna models used in this test were: Ashtech D/M choke ring, Trimble D/M choke ring, Trimble Zephyr, and the NovAtel GPS-702. Two stations, spaced within 30 meters, were used in the test. Both had the characteristics similar to the stations of the TAMDEF network, i.e., the UNAVCO fixed-height, force-centered level mounts with a constant antenna offset were used, ensuring extreme stability of the antenna/ mount/pin set up. During each of the four 3-day test data collection sessions, a reference station was occupied continuously with the Ashtech D/M choke ring antenna, while the second station was occupied by the tested antennas, one 3-day session for each antenna type. The coordinate differences were produced using software optimized for the analysis of data collected over short baselines. Each solution incorporated the NGS antenna calibration data appropriate for each antenna model. Hourly and 24-hour solutions were analyzed for repeatability and compared to the standard baseline coordinate differences. No significant variation was observed when comparing the same type of antennas and when switching antennas at the test site using daily solutions. An mm-level scatter can be observed comparing different antennas over the 1-hour solutions; it is smaller for the horizontal components, as compared to the vertical direction. At this point, it can be concluded that the standard antenna calibration models from NGS used for each antenna involved in this test did not result in any significant variation in the daily results, but with some in the hourly results. Thus, based on this fact, the antenna types tested here could be used in the future TAMDEF campaigns, where 24-hour solutions are normally used for deformation monitoring. These results can serve as good guidance to any future use of GPS equipment in Antarctica.
The ionospheric impact on GPS performance in southern polar region
Hong, C.-K.; Grejner-Brzezinska, D. A.; Arslan, N.; Willis, M.; Hothem, L.
2006-01-01
The primary objective of this paper is to present the results of the study of the effects of varying ionospheric conditions on the GPS signal tracking in the southern polar region. In the first stage of this study, the data collected by the OSU/USGS team in October-November 2003 within the TAMDEF (Transantarctic Mountains Deformation) network were used together with some IGS Antarctic stations to study the effect of severe ionospheric storms on GPS hardware. Note that TAMDEF is a joint USGS/OSU project with the primary objective of measuring crustal motion in the Transantarctic Mountains of Southern Victoria Land using GPS techniques. This study included ten Antarctic stations equipped with different dual-frequency GPS hardware, and the data were evaluated for two 24-hour periods of severe ionospheric storm (2003/10/29) and moderate ionospheric conditions (minor storm of 2003/11/11). The results of this study were presented at the LAG Assembly in Cairns, Australia (Grejner-Brzezinska et al., 2005). Additional tests, in a more controlled environment, were carried out at the US Antarctic station, McMurdo, between January 10 and February 6, 2006, under varying ionospheric conditions, where several different types of receivers were connected to the same antenna located on the rooftop of the Crary Laboratory (the primary test site). In this scenario, each antenna was subject to identical ionospheric effects during each day of the test, and no spatial decorrelation effects were present, as seen in the previous study, due to the spatial separation of the receivers tested. It should be noted, however, that no moderate or severe ionospheric storms occurred during the experiment, so, unfortunately, this type of conditions was not tested here. The test was repeated with different receivers connected to different antenna types; a total of four 5-day sessions were carried out. The following receiver types were used at the primary site: Trimble 5700, Ashtech Z-Surveyor, JNS Euro-80 and Novatel DL-4, with the following antennas: Trimble Zephyr Geodetic, Ashtech D/M and Ashtech E/M chokering. In addition, data collected by the MCM4 IGS station, MCMD UNAVCO station, and CRAR USGS station, all located within 300 m from the primary test site, were used in the analyses. These stations were equipped with the following receiver/antenna combinations: ADA SNR-12/AOAD/MJT chokering (MCM4), Trimble NETRS/AOAD/MJT chokering (MCMD), and TPS ODYSEY_E/JPSREGANT_DD_E (CRAR). The UNAVCO TEQC software was used to carry out the analyses. Depending on the data sampling rate and the mask angle, the expected numbers of observations per receiver/satellite were compared to the actual number of measurements collected during the ionospheric events, with a special emphasis on L2 data. A total number of cycle slips and losses of lock were computed and compared among the hardware types. The results presented here indicate that there is no significant effects on the GPS receivers during minor ionospheric storms (Kp<5). However, the results reported in ibid, indicate significant differences in the hardware performance under severe ionospheric storms. Thus, careful hardware selection is needed to assure data quality/continuity when observations may be affected by severe ionospheric disturbances, while under calm to minor ionospheric activity level there is no significant difference in performance among the hardware tested here.
Application of nanoscale zero valent iron (NZVI) for groundwater remediation in Europe.
Mueller, Nicole C; Braun, Jürgen; Bruns, Johannes; Černík, Miroslav; Rissing, Peter; Rickerby, David; Nowack, Bernd
2012-02-01
Nanoscale zero valent iron (NZVI) is emerging as a new option for the treatment of contaminated soil and groundwater targeting mainly chlorinated organic contaminants (e.g., solvents, pesticides) and inorganic anions or metals. The purpose of this article is to give a short overview of the practical experience with NZVI applications in Europe and to present a comparison to the situation in the USA. Furthermore, the reasons for the difference in technology use are discussed. The results in this article are based on an extensive literature review and structured discussions in an expert workshop with experts from Europe and the USA. The evaluation of the experiences was based on a SWOT (strength, weakness, opportunity, threat) analysis. There are significant differences in the extent and type of technology used between NZVI applications in Europe and the USA. In Europe, only three full-scale remediations with NZVI have been carried out so far, while NZVI is an established treatment method in the USA. Bimetallic particles and emulsified NZVI, which are extensively used in the USA, have not yet been applied in Europe. Economic constraints and the precautionary attitude in Europe raise questions regarding whether NZVI is a cost-effective method for aquifer remediation. Challenges to the commercialization of NZVI include mainly non-technical aspects such as the possibility of a public backlash, the fact that the technology is largely unknown to consultants, governments and site owners as well as the lack of long-term experiences. Despite these concerns, the results of the current field applications with respect to contaminant reduction are promising, and no major adverse impacts on the environment have been reported so far. It is thus expected that these trials will contribute to promoting the technology in Europe.
NASA Astrophysics Data System (ADS)
Hutton, J. J.; Gopaul, N.; Zhang, X.; Wang, J.; Menon, V.; Rieck, D.; Kipka, A.; Pastor, F.
2016-06-01
For almost two decades mobile mapping systems have done their georeferencing using Global Navigation Satellite Systems (GNSS) to measure position and inertial sensors to measure orientation. In order to achieve cm level position accuracy, a technique referred to as post-processed carrier phase differential GNSS (DGNSS) is used. For this technique to be effective the maximum distance to a single Reference Station should be no more than 20 km, and when using a network of Reference Stations the distance to the nearest station should no more than about 70 km. This need to set up local Reference Stations limits productivity and increases costs, especially when mapping large areas or long linear features such as roads or pipelines. An alternative technique to DGNSS for high-accuracy positioning from GNSS is the so-called Precise Point Positioning or PPP method. In this case instead of differencing the rover observables with the Reference Station observables to cancel out common errors, an advanced model for every aspect of the GNSS error chain is developed and parameterized to within an accuracy of a few cm. The Trimble Centerpoint RTX positioning solution combines the methodology of PPP with advanced ambiguity resolution technology to produce cm level accuracies without the need for local reference stations. It achieves this through a global deployment of highly redundant monitoring stations that are connected through the internet and are used to determine the precise satellite data with maximum accuracy, robustness, continuity and reliability, along with advance algorithms and receiver and antenna calibrations. This paper presents a new post-processed realization of the Trimble Centerpoint RTX technology integrated into the Applanix POSPac MMS GNSS-Aided Inertial software for mobile mapping. Real-world results from over 100 airborne flights evaluated against a DGNSS network reference are presented which show that the post-processed Centerpoint RTX solution agrees with the DGNSS solution to better than 2.9 cm RMSE Horizontal and 5.5 cm RMSE Vertical. Such accuracies are sufficient to meet the requirements for a majority of airborne mapping applications.
Progress on Suffa Large Radiotelescope Project
NASA Astrophysics Data System (ADS)
Shanin, G. I.; Hojaev, A. S.
2006-08-01
The large-scale radio astronomy facility complex (analogous to the GBT at NRAO) is being created not far from Samarkand (Uzbekistan) on Suffa plateau at 2300 m (Trimble,2001). Originally it was designed as a basic part of the Earth-Space VLBI system (Kardashev et al,1995; URL http://www.asc.rssi.ru/suffa/) and contains the radio telescope for 0.8-60 mm band with 70 [Author ID2: at Fri Jul 14 10:39:00 2006 ]m main reflector, two removable subreflectors; satellite communication station; data receiving and processing system and other necessary infrastructure. The adaptive optics principle will be used for control the surface of the main mirror consisted of 1200 trapezoid panels. The site location provides good seeing conditions for cm-mm range. Averaged annual atmospheric transmission coefficients at zenith were derived as 0.90-0.98 for 3.1 mm and 5.8 mm wavelengths and about 0.60 for 1.36 (Hojaev & Shanin, 1996). The project started as far back as the period of the Soviet Union was stalled since its disintegration. Quite recently the firm decision on completing the project has been endorsed by our Governments, and Russia will invest for these; therefore the project's layouts have been considerably modernizated and updated in order to build up the state-of-art instrument. It should be operational in 2009. Now we are arranging the scientific consortium to further explore the Suffa site more deep and to learn the main 'radio astro climate' parameters by means of a new technology ('radioseeing', radio transparency in different submm, mm and cm bands, PWV, their intercorrelation and correlation with meteoparameters) for the atmosphere modelling at the site and try to forecast the "radio-weather" for reliably planning the scientific schedule of the future telescope. References: Kardashev N.S., Andreyanov V.V., Gvamichava A.S., Likhachev S.F., and Slysh V.I., 1995, , Acta Astronautica, vol.37, p.271 Hojaev A.S., Shanin G.I., 1996, JKAS, v.29 , p.S411 Trimble, V., 2001, A Year of Discovery: Astronomy Highlights of 2000, Sky and Telescope, vol.101, N.2, p.51
Progress on Suffa Large Radiotelescope Project
NASA Astrophysics Data System (ADS)
Shanin, G. I.; Hojaev, A. S.
2006-08-01
The large-scale radio astronomy facility complex (analogous to the GBT at NRAO) is being created not far from Samarkand (Uzbekistan) on Suffa plateau at 2300 m (Trimble,2001). Originally it was designed as a basic part of the Earth-Space VLBI system (Kardashev et al,1995; URL http://www.asc.rssi.ru/suffa/) and contains the radio telescope for 0.8-60 mm band with 70m main reflector, two removable subreflectors; satellite communication station; data receiving and processing system and other necessary infrastructure. The adaptive optics principle will be used for control the surface of the main mirror consisted of 1200 trapezoid panels. The site location provides good seeing conditions for cm-mm range. Averaged annual atmospheric transmission coefficients at zenith were derived as 0.90-0.98 for 3.1 mm and 5.8 mm wavelengths and about 0.60 for 1.36 (Hojaev & Shanin, 1996). The project started as far back as the period of the Soviet Union was stalled since its disintegration. Quite recently the firm decision on completing the project has been endorsed by our Governments, and Russia will invest for these; therefore the project's layouts have been considerably modernizated and updated in order to build up the state-of-art instrument. It should be operational in 2009. Now we are arranging the scientific consortium to further explore the Suffa site more deep and to learn the main 'radio astro climate' parameters by means of a new technology ('radioseeing', radio transparency in different submm, mm and cm bands, PWV , their intercorrelation and correlation with meteoparameters) for the atmosphere modelling at the site and try to forecast the "radio-weather" for reliably planning the scientific schedule of the future telescope. References: Kardashev N.S., Andreyanov V.V., Gvamichava A.S., Likhachev S.F., and Slysh V.I., 1995, , Acta Astronautica, vol.37, p.271 Hojaev A.S., Shanin G.I., 1996, JKAS, v.29 , p.S411 Trimble, V., 2001, A Year of Discovery: Astronomy Highlights of 2000, Sky and Telescope, vol.101, N.2, p.51
NASA Astrophysics Data System (ADS)
Austin, K. E.; Blume, F.; Berglund, H. T.; Feaux, K.; Gallaher, W. W.; Hodgkinson, K. M.; Mattioli, G. S.; Mencin, D.
2014-12-01
The EarthScope Plate Boundary Observatory (PBO), through a NSF-ARRA supplement, has enhanced the geophysical infrastructure in in the Pacific Northwest by upgrading a total of 282 Plate Boundary Observatory GPS stations to allow the collection and distribution of high-rate (1 Hz), low-latency (<1 s) data streams (RT-GPS). These upgraded stations supplemented the original 100 RT-GPS stations in the PBO GPS network. The addition of the new RT-GPS sites in Cascadia should spur new volcano and earthquake research opportunities in an area of great scientific interest and high geophysical hazard. Streaming RT-GPS data will enable researchers to detect and investigate strong ground motion during large geophysical events, including a possible plate-interface earthquake, which has implications for earthquake hazard mitigation. A Mw 6.9 earthquake occurred on March 10, 2014, off the coast of northern California. As a response, UNAVCO downloaded high-rate GPS data from Plate Boundary Observatory stations within 500 km of the epicenter of the event, providing a good test of network performance.In addition to the 282 stations upgraded to real-time, 22 new meteorological instruments were added to existing PBO stations. Extensive testing of BGAN satellite communications systems has been conducted to support the Cascadia RT-GPS upgrades and the installation of three BGAN satellite fail over systems along the Cascadia margin will allow for the continuation of data flow in the event of a loss of primary communications during in a large geophysical event or other interruptions in commercial cellular networks. In summary, with these additional upgrades in the Cascadia region, the PBO RT-GPS network will increase to 420 stations. Upgrades to the UNAVCO data infrastructure included evaluation and purchase of the Trimble Pivot Platform, servers, and additional hardware for archiving the high rate data, as well as testing and implementation of GLONASS and Trimble RTX positioning on the receivers. UNAVCO staff is working closely with the UNAVCO community to develop data standards, protocols, and a science plan for the use of RT-GPS data.
NASA Astrophysics Data System (ADS)
Dausz, K.; Dittmann, S. T.; Feaux, K.; von Hillebrandt-Andrade, C.; Mattioli, G. S.; Normandeau, J.
2014-12-01
The Continually Operating Caribbean GPS Observational Network (COCONet) is a National Science Foundation (NSF) funded multi-hazard geodetic and meteorological network distributed throughout the Caribbean, which provides infrastructure and capacity building for a broad range of earth science questions. The network is a multi-national collaboration consisting of 46 newly constructed continuous Global Positioning Systems (cGPS) and 21 refurbished existing GPS stations, all co-located with meteorological sensors. One recommendation of the COCONet working group was to improve the vertical reference frame for long-term sea level monitoring. A COCONet supplement was awarded by the NSF to further address this particular objective through the co-location of GPS and tide gauges. This COCOnet infrastructure, along with the new tide gauges, will have broad scientific implications for hazards mitigation, solid earth, and atmospheric science research. UNAVCO engineers have meet with members of the Caribbean tide gauge community to establish target locations and design station layout. Allocated NSF funds allow for the construction of two complete new tide gauge systems each with two complimentary cGPS. Following the recommendations of NOAA and the sea level monitoring community, the two "new" locales will be Port Royal, Jamaica and Puerto Morelos, Mexico. Both locations had previously existing, but currently non-operational tide gauges. UNAVCO engineers will install a Sutron Radar Level Recorder and a backup pressure sensor tide gauge with GOES satellite telemetry. Tide data will be freely available by the Intergovernmental Oceanographic Commission (www.ioc-sealevelmonitoring.org). The NSF supplement also provided funds for adding cGPS to two additional locations where currently functioning tide gauge systems exist. Proposed locations for this additional infrastructure are Barahona, Dominican Republic and Bocas del Toro, Panama. All four locations will feature two standard COCONet cGPS systems consisting of a Trimble Choke Ring GNSS antenna, Trimble NetR9 GPS receiver, and a Vaisala meteorological sensor. All GPS data will be collected, processed and distributed via standard COCONet archiving and processing along with raw meteorological data at coconet.unavco.org.
Atmospheric deposition, CO2, and change in the land carbon sink.
Fernández-Martínez, M; Vicca, S; Janssens, I A; Ciais, P; Obersteiner, M; Bartrons, M; Sardans, J; Verger, A; Canadell, J G; Chevallier, F; Wang, X; Bernhofer, C; Curtis, P S; Gianelle, D; Grünwald, T; Heinesch, B; Ibrom, A; Knohl, A; Laurila, T; Law, B E; Limousin, J M; Longdoz, B; Loustau, D; Mammarella, I; Matteucci, G; Monson, R K; Montagnani, L; Moors, E J; Munger, J W; Papale, D; Piao, S L; Peñuelas, J
2017-08-29
Concentrations of atmospheric carbon dioxide (CO 2 ) have continued to increase whereas atmospheric deposition of sulphur and nitrogen has declined in Europe and the USA during recent decades. Using time series of flux observations from 23 forests distributed throughout Europe and the USA, and generalised mixed models, we found that forest-level net ecosystem production and gross primary production have increased by 1% annually from 1995 to 2011. Statistical models indicated that increasing atmospheric CO 2 was the most important factor driving the increasing strength of carbon sinks in these forests. We also found that the reduction of sulphur deposition in Europe and the USA lead to higher recovery in ecosystem respiration than in gross primary production, thus limiting the increase of carbon sequestration. By contrast, trends in climate and nitrogen deposition did not significantly contribute to changing carbon fluxes during the studied period. Our findings support the hypothesis of a general CO 2 -fertilization effect on vegetation growth and suggest that, so far unknown, sulphur deposition plays a significant role in the carbon balance of forests in industrialized regions. Our results show the need to include the effects of changing atmospheric composition, beyond CO 2 , to assess future dynamics of carbon-climate feedbacks not currently considered in earth system/climate modelling.
de Groot, Anton C; Maibach, Howard I
2010-03-01
Recent US studies have presented case series of patient with allergic contact dermatitis (ACD) allegedly caused by formaldehyde in clothes treated with durable-press chemical finishes (DPCF), which are known formaldehyde releasers. However, the amounts of formaldehyde released by modern DPCF are thought to be well below the levels previously estimated to be able to elicit ACD. The objectives of this review are (i) to investigate whether clothes sold in the USA may contain enough free formaldehyde to elicit ACD in previously sensitized individuals and (ii) to assess the validity of US reports on ACD from formaldehyde in DPCF treated clothes. Literature was examined using various resources. The threshold level for formaldehyde in clothes that may cause ACD in sensitized individuals is unknown; we present data suggesting that levels < 200 ppm will be safe for most patients and that textiles will rarely contain higher amounts. All US studies presenting patients with ACD from formaldehyde in clothes had some weaknesses and in no report was the diagnosis proven beyond doubt. Currently, there is no definite proof that textile ACD from formaldehyde in DPCF in the USA exists. Future research should be directed at establishing the elicitation threshold and the amounts of formaldehyde present in textiles.
Use of X-rays to treat shoulder tendonitis/bursitis: a historical assessment.
Calabrese, Edward J; Dhawan, Gaurav; Kapoor, Rachna
2014-08-01
This article assesses the therapeutic efficacy of ionizing radiation for the treatment of shoulder tendonitis/bursitis in the USA over the period of its use (human 1936-1961; veterinary 1954-1974). Results from ~3,500 human cases were reported in the clinical case studies over 30 articles, and indicated a high treatment efficacy (>90 %) for patients. Radiotherapy was effective with a single treatment. The duration of treatment effectiveness was prolonged, usually lasting until the duration of the follow-up period (i.e., 1-5 years). Therapeutic effectiveness was reduced for conditions characterized as chronic. Similar findings were reported with race horses in the veterinary literature. These historical findings are consistent with clinical studies over the past several decades in Germany, which have used more rigorous study designs and a broader range of clinical evaluation parameters. Radiotherapy treatment was widely used in the mid twentieth century in the USA, but was abandoned following the discovery of anti-inflammatory drugs and the fear of radiation-induced cancer. That X-ray treatment could be an effective means of treating shoulder tendonitis/bursitis, as a treatment option, and is essentially unknown by the current medical community. This paper is the first comprehensive synthesis of the historical use of X-rays to treat shoulder tendonitis/bursitis and its efficacy in the USA.
Duck plague epizootics in the United States, 1967-1995
Converse, K.A.; Kidd, Gregory A.
2001-01-01
In 1967, the first confirmed diagnosis of duck plague (DP) in the USA was made from pekin ducks (Anas platyrhynchos domesticus) on commercial duck farms on Long Island, New York. Within 10 mo, DP was confirmed as the cause of death in migratory waterfowl on a Long Island bay. This paper reviews 120 DP epizootics reported from 1967 to 1995 that involved waterfowl species native to North America or were reported in areas with free-flying waterfowl at risk. Duck plague epizootics occurred in 21 states with the greatest number reported in Maryland (29), New York (18), California (16), and Pennsylvania (13). The greatest frequency of epizootics (86%) was detected during the months of March to June. At least 40 waterfowl species were affected with the highest frequency of epizootics reported in captive or captive-reared ducks including muscovy ducks (Cairina moschata) (68%), mallard ducks (A. platyrhynchos) (18%) and black ducks (A. rubripes) (14%). The greatest number of waterfowl died in three epizootics that involved primarily migratory birds in 1967 and 1994 in New York (USA) and 1973 in South Dakota (USA). The greatest number of DP epizootics reported since 1967 appear to have involved flocks of non-migratory rather than migratory waterfowl; therefore, in our opinion it remains unknown if DP is enzootic in either non-migratory or migratory waterfowl.
Butler, Merlin G.; Manzardo, Ann M.; Heinemann, Janalee; Loker, Carolyn; Loker, James
2016-01-01
Background Prader-Willi syndrome (PWS) is a rare complex neurodevelopmental genetic disorder that is associated with hyperphagia and morbid obesity in humans leading to a shortened life expectancy. This report summarizes the primary causes of death and evaluates mortality trends in a large cohort of individuals with PWS. Methods PWSA (USA) mortality syndrome-specific database of death reports was collected through a cursory bereavement program for PWSA(USA) families using a brief survey created in 1999. Causes of death were descriptively characterized and statistically examined using Cox Proportional Hazards. Results A total of 486 deaths were reported (263 males, 217 females, 6 unknown) between 1973 and 2015 with mean age of 29.5 ± 16 years (2mo–67yrs), 70% occurring in adulthood. Respiratory failure was the most common cause accounting for 31% of all deaths. Males were at increased risk for presumed hyperphagia-related accidents/injuries compared to females and cardiopulmonary factors. PWS maternal disomy 15 genetic subtype showed an increased risk of death from cardiopulmonary factors compared to the deletion subtype. Conclusions These findings highlight the heightened vulnerability towards obesity and hyperphagia-related mortality in PWS. Future research is needed to address critical vulnerabilities such as gender and genetic subtype in the cause of death in PWS. PMID:27854358
Salmonella Newport omphaloarteritis in a stranded killer whale (Orcinus orca) neonate.
Colegrove, Kathleen M; St Leger, Judy A; Raverty, Stephen; Jang, Spencer; Berman-Kowalewski, Michelle; Gaydos, Joseph K
2010-10-01
Salmonella enterica serovar Newport (Salmonella Newport) was isolated from multiple tissues in a neonate killer whale (Orcinus orca) that stranded dead in 2005 along the central coast of California, USA. Necrotizing omphaloarteritis and omphalophlebitis was observed on histologic examination suggesting umbilical infection was the route of entry. Genetic analysis of skin samples indicated that the neonate had an offshore haplotype. Salmonellosis has rarely been identified in free-ranging marine mammals and the significance of Salmonella Newport infection to the health of free-ranging killer whales is currently unknown.
Photographic copy Photograph of 1892 drawing by artist H.W. Locket. ...
Photographic copy Photograph of 1892 drawing by artist H.W. Locket. Original Photographer Unknown. Loose in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. EARLY DESIGN OF DOUBLE TRACK RAILROAD BRIDGE OVER MISSISSIPPI RIVER ABOVE THE CITY OF NEW ORLEANS, LA, U.S.A. TO BE BUILT BY SOUTHERN BRIDGE AND RAILWAY COMPANY. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA
Makarkin, Vladimir N
2017-01-30
Xenoberotha angustialata gen. et sp. nov. (Neuroptera: Berothidae) is described from the early Eocene of the Parachute Creek Member of the Green River Formation (U.S.A., Colorado). It is assigned to Berothinae as an oldest known member of the subfamily based on the presence of scale-like setae on the foreleg coxae. Distal crossveins of the fourth (outer) gradate series which are located very close to the wing margin in Xenoberotha gen. nov. is a character state previously unknown in Berothinae.
[Increase in working hours is an option for improving surgical education in Denmark].
Andresen, Kristoffer; Achiam, Michael Patrich; Rosenberg, Jacob
2013-05-06
Danish surgeons in training have a 37-hour workweek. These are relatively few hours compared with the hours in England and USA where surgeons have a workweek of respectively 48 and 80 hours. The optimal length of a workweek during surgical education is unknown, but studies have shown that surgeons working more hours have improved abilities in clinical judgment. Learning outcome may improve if Danish surgeons in training were allowed to work more hours. We suggest a 37 + 11-hour workweek, where 11 hours are reserved for educational purposes.
Cecilia Payne-Gaposchkin, An Autobiography and Other Recollections
NASA Astrophysics Data System (ADS)
Haramundanis, Katherine
Cecilia Payne-Gaposchkin became acclaimed in her lifetime as the greatest woman astronomer of all time. Her own story of her professional life, work and scientific achievements is augmented by the personal recollections of her daughter, Katherine Haramundanis, as well as a scientific appreciation by Jesse Greenstein, a historical essay by Peggy Kidwell and, in this new edition, an introduction by Virginia Trimble. Payne-Gaposchkin's overwhelming love for astronomy was her personal guiding light, and her attitude and approach have lessons for all. She received many prestigious awards for her outstanding contributions to science and in 1956 became the first woman to be advanced to the rank of Professor at Harvard University, as well as being the first woman departmental chair. This book will interest both astronomers and those studying the advancement of the position and status of women in society.
Krstolic, Jennifer L.; Hayes, Donald C.
2010-01-01
Data collected with the GeoXT Trimble GPS unit using ArcPad 6.1. (summer 2006-2007). Files were created within a geodatabase to create a data dictionary for use in ArcPad during data collection. Drop down lists for habitat type, substrate, depth, width, length, and descriptions were included. Data files produced on the GeoXT were point shapefiles that could be checked back into the geodatabase and viewable as a layer. Points were gathered while canoeing along the South Fork Shenandoah River. Each location marked a change in meso-scale habitat type. GPS points were supplemented with GIS-derived points in areas where manual measurements were made. The points were used to generate a line coverage. This coverage represents physical habitat at a meso-scale (width of stream).
Clark-Reyna, Stephanie E.; Grineski, Sara E.; Collins, Timothy W.
2015-01-01
Children in low-income neighborhoods tend to be disproportionately exposed to environmental toxicants. This is cause for concern because exposure to environmental toxicants negatively affect health, which can impair academic success. To date, it is unknown if associations between air toxics and academic performance found in previous school-level studies persist when studying individual children. In pairing the National Air Toxics Assessment (NATA) risk estimates for respiratory and diesel particulate matter risk disaggregated by source, with individual-level data collected through a mail survey, this paper examines the effects of exposure to residential environmental toxics on academic performance for individual children for the first time and adjusts for school-level effects using generalized estimating equations. We find that higher levels of residential air toxics, especially those from non-road mobile sources, are statistically significantly associated with lower grade point averages among fourth and fifth grade school children in El Paso (Texas, USA). PMID:27034529
Marek, Paul E; Krejca, Jean K; Shear, William A
2016-01-01
Members of the family Siphonorhinidae Cook, 1895 are thread-like eyeless millipedes that possess an astounding number of legs, including one individual with 750. Due to their cryptic lifestyle, rarity in natural history collections, and sporadic study over the last century, the family has an unclear phylogenetic placement, and intrafamilial relationships remain unknown. Here we report the discovery of a second species of Illacme , a millipede genus notable for possessing the greatest number of legs of any known animal on the planet. Illacme tobini sp. n. is described from a single male collected in a cave in Sequoia National Park, California, USA. After 90 years since the description of Illacme , the species represents a second of the genus in California. Siphonorhinidae now includes Illacme Cook & Loomis, 1928 (two species, USA), Kleruchus Attems, 1938 (one species, Vietnam), Nematozonium Verhoeff, 1939 (one species, South Africa) and Siphonorhinus Pocock, 1894 (eight species, India, Indonesia, Madagascar, Vietnam).
Marek, Paul E.; Krejca, Jean K.; Shear, William A.
2016-01-01
Abstract Members of the family Siphonorhinidae Cook, 1895 are thread-like eyeless millipedes that possess an astounding number of legs, including one individual with 750. Due to their cryptic lifestyle, rarity in natural history collections, and sporadic study over the last century, the family has an unclear phylogenetic placement, and intrafamilial relationships remain unknown. Here we report the discovery of a second species of Illacme, a millipede genus notable for possessing the greatest number of legs of any known animal on the planet. Illacme tobini sp. n. is described from a single male collected in a cave in Sequoia National Park, California, USA. After 90 years since the description of Illacme, the species represents a second of the genus in California. Siphonorhinidae now includes Illacme Cook & Loomis, 1928 (two species, USA), Kleruchus Attems, 1938 (one species, Vietnam), Nematozonium Verhoeff, 1939 (one species, South Africa) and Siphonorhinus Pocock, 1894 (eight species, India, Indonesia, Madagascar, Vietnam). PMID:27833431
Alloionema californicum n. sp. (Nematoda: Alloionematidae): a new alloionematid from USA.
Nermuť, Jiří; Půža, Vladimír; Mráček, Zdeněk; Lewis, Edwin
2016-11-07
A new species of the family Alloionematidae was isolated from a rotten winged gourd at White Crane Garden, San Francisco, USA, sampled by Christopher Nelson in November 2010, and a live culture is deposited in Félix Lab Strain Database (http://www.justbio.com/worms/index.php), IBENS, Paris, France. Specimens from the culture have been examined. Both morphologically and molecularly, the nematode described herein as Alloionema californicum n. sp. differs from the other alloionematid species, A. appendiculatum and Neoalloionema tricaudatum. It is characterised by having a narrow stoma, 2.5-3.5 or 4 times longer than broad in adults or dauer juveniles respectively. Lateral fields are not present in adults but occur as one prominent ridge in dauers. Males have no bursa, six pairs of genital papillae and one single papilla. Dauers have large apparent phasmids in the middle of the tail. The ecology of the newly described species is unknown but probably it is a saprobic bacteriophagous nematode preferring rotting organic material.
A Plant-Based Proxy for the Oxygen Isotope Ratio of Atmospheric Water Vapor
NASA Astrophysics Data System (ADS)
Helliker, B.
2007-12-01
Atmospheric water vapor is a major component of the global hydrological cycle, but the isotopic balance of vapor is largely unknown. It is shown here that the oxygen isotope ratio of leaf water in the epiphytic Crassulacean acid metabolism (CAM) plant Tillandsia usneoides (Spanish Moss) is controlled by the oxygen isotope ratio of atmospheric water vapor in both field and lab studies. Assuming that the leaf-water isotopic signature (and hence the atmospheric water vapor signature) is recorded in plant organic material, the atmospheric water vapor oxygen isotope ratios for Miami, Florida (USA) were reconstructed for several years from 1878 to 2005 using contemporary and herbarium specimens. T. usneoides ranges from Virginia, USA southwards through the tropics to Argentina, and the CAM epiphytic lifeform is widespread in other species. Therefore, epiphytes may be used to reconstruct the isotope ratio of atmospheric water for spatial scales that span over 60° of latitude and temporal scales that cover the last century of global temperature increase.
NASA Astrophysics Data System (ADS)
Payne-Gaposchkin, Cecilia; Haramundanis, Katherine; Greenstein, Introduction by Jesse; Trims, Virginia; Kidwell, Peggy
1996-03-01
Cecilia Payne-Gaposchkin: an Introduction Virginia Trimble; An introduction to The Dyer's Hand Jesse L. Greenstein; A historical introduction to The Dyer's Hand Peggy A. Kidwell; A personal recollection Katherine Haramundanis; The Dyer's Hand: an autobiography Cecilia Payne-Gaposchkin; Dedication; Foreword; Part I. The Vision Splendid: 1. Backgrounds; 2. Beginnings; 3. Prelude to education; 4. Birth of a dream; 5. Dramatic interlude; 6. The dream fulfilled; 7. Pathway to the stars; Part II. The Light Of Common Day: 8. England and the United States; 9. Harvard College Observatory; 10. The cradle of astrophysics; 11. Harlow Shapley; 12. Stellar atmospheres; 13. Spectra and luminosities; 14. Editorial experiences; 15. Visiting astronomers; 16. At the cross roads; Part III. The Dyer's Hand Subdued: 17. Turning point; 18. Prolegomena to various stars; 19. International problems; 20. End of an era; 21. Retrospect; Part IV. Reflections: 22. On being a woman; 23. Science and myth; 24. Worlds not realized; Bibliography of works by Cecilia Payne-Gaposchkin; Postlude; Index.
View of Mission Control Center celebrating conclusion of Apollo 11 mission
NASA Technical Reports Server (NTRS)
1969-01-01
Overall view of the Mission Operations Control Room in the Mission Control Center, bldg 30, Manned Spacecraft Center (MSC), at the conclusion of the Apollo 11 lunar landing mission. The television monitor shows President Richard M. Nixon greeting the Apollo 11 astronauts aboard the U.S.S. Hornet in the Pacific recovery area (40301); NASA and MSC Officials join the flight controllers in celebrating the conclusion of the Apollo 11 mission. From left foreground Dr. Maxime A. Faget, MSC Director of Engineering and Development; George S. Trimble, MSC Deputy Director; Dr. Christopher C. Kraft Jr., MSC Director fo Flight Operations; Julian Scheer (in back), Assistant Adminstrator, Offic of Public Affairs, NASA HQ.; George M. Low, Manager, Apollo Spacecraft Program, MSC; Dr. Robert R. Gilruth, MSC Director; and Charles W. Mathews, Deputy Associate Administrator, Office of Manned Space Flight, NASA HQ (40302).
Evaluation of terrestrial photogrammetric point clouds derived from thermal imagery
NASA Astrophysics Data System (ADS)
Metcalf, Jeremy P.; Olsen, Richard C.
2016-05-01
Computer vision and photogrammetric techniques have been widely applied to digital imagery producing high density 3D point clouds. Using thermal imagery as input, the same techniques can be applied to infrared data to produce point clouds in 3D space, providing surface temperature information. The work presented here is an evaluation of the accuracy of 3D reconstruction of point clouds produced using thermal imagery. An urban scene was imaged over an area at the Naval Postgraduate School, Monterey, CA, viewing from above as with an airborne system. Terrestrial thermal and RGB imagery were collected from a rooftop overlooking the site using a FLIR SC8200 MWIR camera and a Canon T1i DSLR. In order to spatially align each dataset, ground control points were placed throughout the study area using Trimble R10 GNSS receivers operating in RTK mode. Each image dataset is processed to produce a dense point cloud for 3D evaluation.
GNSS CORS hardware and software enabling new science
NASA Astrophysics Data System (ADS)
Drummond, P.
2009-12-01
GNSS CORS networks are enabling new opportunities for science and public and private sector business. This paper will explore how the newest geodetic monitoring software and GNSS receiver hardware from Trimble Navigation Ltd are enabling new science. Technology trends and science opportunities will be explored. These trends include the installation of active GNSS control, automation of observations and processing, and the advantages of multi-observable and multi-constellation observations, all performed with the use of off the shelf products and industry standard open-source data formats. Also the possibilities with moving science from an after-the-fact postprocessed model to a real-time epoch-by-epoch solution will be explored. This presentation will also discuss the combination of existing GNSS CORS networks with project specific installations used for monitoring. Experience is showing GNSS is able to provide higher resolution data than previous methods, providing new tools for science, decision makers and financial planners.
Hart, Kristen M.; Sartain-Iverson, Autumn R.; Fujisaki, Ikuko
2015-01-01
We demonstrate a previously unknown link between Dry Tortugas nesting beaches and Bahamas residence areas; 17/39 (43.6%) of nesting loggerheads tagged in and tracked from the Dry Tortugas take up residence at sites in the Bahamas. Residence area estimates for these turtles were similar in size to previous foraging area estimates for two turtles tracked to the Bahamas in other studies. We show inter-annual residence area repeatability, and that residence areas of different individuals generally did not overlap. We suggest that these loggerheads possibly establish territories.
Butler, Merlin G; Manzardo, Ann M; Heinemann, Janalee; Loker, Carolyn; Loker, James
2017-06-01
Prader-Willi syndrome (PWS) is a rare, complex, neurodevelopmental genetic disorder that is associated with hyperphagia and morbid obesity in humans and leads to a shortened life expectancy. This report summarizes the primary causes of death and evaluates mortality trends in a large cohort of individuals with PWS. The US Prader-Willi Syndrome Association (PWSA (USA)) syndrome-specific database of death reports was collected through a cursory bereavement program for PWSA (USA) families using a brief survey created in 1999. Causes of death were descriptively characterized and statistically examined using Cox proportional hazards. A total of 486 deaths were reported (263 males, 217 females, 6 unknown) between 1973 and 2015, with mean age of 29.5 ± 16 years (2 months-67 years); 70% occurred in adulthood. Respiratory failure was the most common cause, accounting for 31% of all deaths. Males were at increased risk for presumed hyperphagia-related accidents/injuries and cardiopulmonary factors compared to females. PWS maternal disomy 15 genetic subtype showed an increased risk of death from cardiopulmonary factors compared to the deletion subtype. These findings highlight the heightened vulnerability to obesity and hyperphagia-related mortality in PWS. Future research is needed to address critical vulnerabilities such as gender and genetic subtype in the cause of death in PWS.Genet Med advance online publication 17 November 2016.
Physical Properties of Venous Stents: An Experimental Comparison.
Dabir, Darius; Feisst, Andreas; Thomas, Daniel; Luetkens, Julian A; Meyer, Carsten; Kardulovic, Ana; Menne, Matthias; Steinseifer, Ulrich; Schild, Hans H; Kuetting, Daniel L R
2018-06-01
Iliocaval obstruction is a substantial contributor to chronic venous insufficiency and is increasingly being treated endovascularly with angioplasty and stent placement. Utilization of an appropriate stent for treatment is pivotal; however, until today, mechanical properties of venous stents remain unknown. We analyzed the radial resistive force, the chronic outward force, as well as the crush resistance of seven stent models [Zilver Vena (Cook, Bjaeverskov, Denmark), Sinus Venous, Sinus Obliquus and Sinus XL Flex (Optimed, Ettlingen, Germany), Vici (Veniti; St. Louis, USA), Wallstent (Boston Scientific, Marlborough, USA), and Venovo (Bard, Tempe, USA)] in vitro using a radial force testing machine (RX-650, Machine Solutions Inc., Flagstaff, AZ, USA) and a hardness testing machine (zwickiLine, Zwick Roell, Ulm, Germany). The Sinus Obliquus revealed the highest radial resistive force (19.41 N/cm) and the highest chronic outward force at 50 and 30% nominal diameter (7.93 N/cm at 50%, 16.97 N/cm at 30%) while the Venovo revealed the highest chronic outward force at 90 and 80% nominal diameter (4.83 N/cm at 90%, 5.37 N/cm at 80%). The radial resistive force and the chronic outward force of the Wallstent greatly depended on whether the stent ends were fixated. The Wallstent revealed the highest crush resistance at nominal diameters of 90% (0.46 N/cm) to 60% (1.16 N/cm). The Sinus Obliquus revealed the highest crush resistance at a nominal diameter of 50% (1.41 N/cm). Venous stents greatly differ regarding their mechanical properties. These results should be considered when choosing an appropriate stent for the treatment of venous obstruction.
Lancaster, Cady; Espinoza, Edgard
2012-05-15
International trade of several Dalbergia wood species is regulated by The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). In order to supplement morphological identification of these species, a rapid chemical method of analysis was developed. Using Direct Analysis in Real Time (DART) ionization coupled with Time-of-Flight (TOF) Mass Spectrometry (MS), selected Dalbergia and common trade species were analyzed. Each of the 13 wood species was classified using principal component analysis and linear discriminant analysis (LDA). These statistical data clusters served as reliable anchors for species identification of unknowns. Analysis of 20 or more samples from the 13 species studied in this research indicates that the DART-TOFMS results are reproducible. Statistical analysis of the most abundant ions gave good classifications that were useful for identifying unknown wood samples. DART-TOFMS and LDA analysis of 13 species of selected timber samples and the statistical classification allowed for the correct assignment of unknown wood samples. This method is rapid and can be useful when anatomical identification is difficult but needed in order to support CITES enforcement. Published 2012. This article is a US Government work and is in the public domain in the USA.
NASA Astrophysics Data System (ADS)
Jackson, Michael; Passmore, Paul; Zimakov, Leonid; Raczka, Jared
2014-05-01
One of the fundamental requirements of an Earthquake Early Warning (EEW) system (and other mission critical applications) is to quickly detect and process the information from the strong motion event, i.e. event detection and location, magnitude estimation, and the peak ground motion estimation at the defined targeted site, thus allowing the civil protection authorities to provide pre-programmed emergency response actions: Slow down or stop rapid transit trains and high-speed trains; shutoff of gas pipelines and chemical facilities; stop elevators at the nearest floor; send alarms to hospitals, schools and other civil institutions. An important question associated with the EEW system is: can we measure displacements in real time with sufficient accuracy? Scientific GNSS networks are moving towards a model of real-time data acquisition, storage integrity, and real-time position and displacement calculations. This new paradigm allows the integration of real-time, high-rate GNSS displacement information with acceleration and velocity data to create very high-rate displacement records. The mating of these two instruments allows the creation of a new, very high-rate (200 Hz) displacement observable that has the full-scale displacement characteristics of GNSS and high-precision dynamic motions of seismic technologies. It is envisioned that these new observables can be used for earthquake early warning studies and other mission critical applications, such as volcano monitoring, building, bridge and dam monitoring systems. REF TEK a Division of Trimble has developed the integrated GNSS/Accelerograph system, model 160-09SG, which consists of REF TEK's fourth generation electronics, a 147-01 high-resolution ANSS Class A accelerometer, and Trimble GNSS receiver and antenna capable of real time, on board Precise Point Positioning (PPP) techniques with satellite clock and orbit corrections delivered to the receiver directly via L-band satellite communications. The test we conducted with the 160-09SG Recorder is focused on the characteristics of GNSS and seismic sensors in high dynamic environments, including historic earthquakes replicated on a shake table, over a range of displacements and frequencies. The main goals of the field tests are to explore the optimum integration of these sensors from a filtering perspective including simple harmonic impulses over varying frequencies and amplitudes and under the dynamic conditions of various earthquake scenarios.
Improvements in GPS precision: 10 Hz to one day
NASA Astrophysics Data System (ADS)
Choi, Kyuhong
Seeking to understand Global Positioning System (GPS) measurements and the positioning solutions in various time intervals, this dissertation improves the consistency of pseudorange measurements from different receiver types, processes 30 s interval data with optimized filtering techniques, and analyzes very-high-rate data with short arc lengths and baseline noise. The first project studies satellite-dependent biases between C/A and P1 codes. Calibrating these biases reduces the inconsistency of satellite clocks, improving the ambiguity resolution which allows for higher position precision. Receiver-dependent biases for two receivers are compared with the bias products of Center for Orbit Determination in Europe (CODE). Baseline lengths ranging up to ˜2,100km are tested with the receiver-specific biases; they resolve more phase ambiguity by 4.3% than using CODE's products. The second project analyzes 1 s and 30 s interval GPS data of the 2003 Tokachi-Oki earthquake. For 1 Hz positioning, Iterative Tropospheric Estimation (ITE) method improves vertical precision. While equalized sidereal filtering reduces noise for multipath-dominant 30--300 s periods, it can cause long-term drifts in the timeseries. A study of postseismic deformation after the Tokachi-Oki earthquake uses 30 s interval position estimations to test multiple filtering strategies to maximize precision using lower-rate data. On top of the residual stacking, estimation of a random walk constraint of sigmaDelta = 1.80 cm/ hr shows maximum noise reduction capability while retaining the real deformation signal. These techniques enhance our grasp of fault response in the aftermath of great earthquakes. The third project probes noise floor characteristics of very-high-rate (> 1 Hz) GPS data. A hybrid method, designed and tested to resolve phase biases, minimizes computational burdens while keeping the quality of ambiguity-fixed solutions. Noise characteristics are compared after an analysis of 5 and 10 Hz Ashtech MicroZ and ZFX as well as Trimble NetRS receivers. The Trimble NetRS receiver noise has a timeseries standard deviation double that of Ashtech MicroZ receivers. Also, the power spectral density function has a 0.1 Hz peak. Noise power shows white noise for the frequency range from 2 Hz and higher. Each research project assesses the methods to reduce the noises and/or biases in various time intervals. Each method considered in this dissertation will fulfill the needs for scientific applications.
1984-01-01
A consultative meeting was convened by the World Health Organization in Geneva on 22-25 November 1983 to assess the present situation of AIDS (the acquired immunodeficiency syndrome) in the world and to encourage collaboration between the different nations affected by this disease. AIDS was first reported in the USA in 1981, but probably existed there as early as 1978. Soon after its recognition in the USA, similar cases were identified in other areas of the world. In most western European countries and Canada, the epidemiological pattern is very similar to that in the United States, the majority of cases being in homosexual men. In other areas such as equatorial Africa and the Caribbean, the pattern seems to be different with no identifiable risk factors for the majority of cases. The disease is manifested by opportunistic infections and/or selected malignancies, with apparent differences in the clinical presentation between the cases in North America and Europe, on the one hand, and those in the tropics. To date there is no treatment that has significantly improved the underlying cellular immune deficiency, and the mortality is very high. The etiology of AIDS is unknown, but the epidemiological pattern is most consistent with its being caused by a transmissible agent; retroviruses come on top of the list of candidate agents. Despite the unknown etiology and the lack of laboratory diagnostic tests, sufficient information is available to permit health authorities to make recommendations that may reduce appreciably the incidence of the disease. AIDS is an important health problem in a number of countries and has international implications. Collaborative laboratory, epidemiological and clinical research between countries is needed to accelerate control efforts. In the meantime, WHO will coordinate exchange of information among countries. ImagesFig. 1 PMID:6331905
Ahmed, Mohammed; Kumari, Suneeta; Manali, Partam; Sonje, Snezana; Malik, Mansoor
2016-10-01
Safety and quality concerns regarding over the counter sexual enhancement products sold in the USA market pose a major health risk to the general public. Nevertheless, the use of herbal medicines continues to expand rapidly across world and many people perceive usage of herbal medication as a safe and reliable way to improve health outcome. The safety of herbal supplements has become a globally major concern in national and international health authorities due to increasing adverse events and adulterations associated with usage of herbal medications. These non FDA approved products with unknown ingredients are widely accessible for purchase ranging from local food, drug stores and to the internet. These Erectile Dysfunction (ED) pills may contain Sildenafil, the active ingredient of Viagra in much higher quantity then legally prescribed by a licensed physician or they may contain unknown quantities of Thiosildenafil, the active ingredient in Cialis. The types of chemicals found in these medications are making it harder for regulatory authorities to track them down. These products keep the consumer in the dark in terms of the quantity, ingredients, effectiveness and possible side effects. These sexual enhancement products are being sold as safe and natural with false hopes to resolve erectile dysfunction. Patients who are prone to impulsive hypersexual behavior such as patients with bipolar disorder, substance use, borderline personality disorder and those who may feel adamant to discuss erectile dysfunction with their physicians are more likely to become the victims of using illicit medications/ drugs with serious health risks consequences. We present a case report of an individual with bipolar disorder and hypersexual behavior who became victim to over the counter sexual enhancement products/supplements which caused serious health and life threatening consequences.
Fuangarworn, Marut; Norton, Roy A
2013-01-01
A new genus and species of enarthronote oribatid mite, Psammochthonius kethleyi n.g., n. sp., is described and illustrated based on adult and immature specimens collected from coastal sandy soil in Thailand (Phangnga), Brazil (SAo Paulo) and the U.S.A. (Mississippi). Analysis shows that it is a member of Hypochthonioidea, but not of any named family, so the monobasic family Psammochthoniidae n. fain. is proposed. Traits that are unique among hypochthonioid mites include an adult body length under 250 microm, a functionally trichoid body form (postpedal flexing), strong lateral displacement of setae in row e, which insert on a unique form of transverse scissure, subcapitular stenarthry, leg IV vestiges and a possible precocious genital swelling in the larva, apparent absence of an anal segment, and a highly regressed leg setation. The latter two, and some other traits that were previously unknown in Hypochthonioidea, suggest that Psammochthoniidae represents the first clearly paedomorphic lineage in this diverse superfamily. Like all other known hypochthonioid mites, P. kethleyi appears to be thelytokous.
Hart, Kristen M.; Sartain-Iverson, Autumn R.; Fujisaki, Ikuko; Pratt, Harold L.; Morley, Danielle; Feeley, Michael W.
2012-01-01
To determine habitat-use patterns of sub-adult hawksbills Eretmochelys imbricata, we conducted satellite- and acoustic-tracking of 3 turtles captured in August 2008 within Dry Tortugas National Park (DRTO), south Florida, USA, in the Gulf of Mexico; turtles ranged in size from 51.9 to 69.8 cm straight carapace length. After 263, 699, and 655 d of residence in the park, turtles migrated out of the DRTO. Within the park, core-use areas (i.e. 50% kernel density estimates) were 9.2 to 21.5 km2; all 3 turtle core-use areas overlapped in an area 6.1 km2 within a zone of the park with multiple human uses (e.g. fishing, anchoring). Two turtles migrated to Cuba and ceased transmitting after 320 and 687 tracking days; the third turtle migrated toward Key West, Florida, and ceased transmitting after 884 tracking days. The present study highlights previously unknown regional connections for hawksbills, possible turtle-harvest incidents, and fine-scale habitat use of sub-adult hawksbills within a United States National Park.
Bateman, H.L.; Nagler, P.L.; Glenn, E.P.
2013-01-01
The biocontrol agent, northern tamarisk beetle (Diorhabda carinulata), has been used to defoliate non-native saltcedar (Tamarix spp.) in USA western riparian systems since 2001. Biocontrol has the potential to impact biotic communities and climatic conditions in affected riparian areas. To determine the relationships between biocontrol establishment and effects on vegetation and climate at the plot and landscape scales, we measured temperature, relative humidity, foliage canopy, solar radiation, and used satellite imagery to assess saltcedar defoliation and evapotranspiration (ET) along the Virgin River in the Mojave Desert. Following defoliation solar radiation increased, daily humidity decreased, and maximum daily temperatures tended to increase. MODIS and Landsat satellite imagery showed defoliation was widespread, resulting in reductions in ET and vegetation indices. Because biocontrol beetles are spreading into new saltcedar habitats on arid western rivers, and the eventual equilibrium between beetles and saltcedar is unknown, it is necessary to monitor trends for ecosystem functions and higher trophic-level responses in habitats impacted by biocontrol.
Using Social Media to Identify Sources of Healthy Food in Urban Neighborhoods.
Gomez-Lopez, Iris N; Clarke, Philippa; Hill, Alex B; Romero, Daniel M; Goodspeed, Robert; Berrocal, Veronica J; Vinod Vydiswaran, V G; Veinot, Tiffany C
2017-06-01
An established body of research has used secondary data sources (such as proprietary business databases) to demonstrate the importance of the neighborhood food environment for multiple health outcomes. However, documenting food availability using secondary sources in low-income urban neighborhoods can be particularly challenging since small businesses play a crucial role in food availability. These small businesses are typically underrepresented in national databases, which rely on secondary sources to develop data for marketing purposes. Using social media and other crowdsourced data to account for these smaller businesses holds promise, but the quality of these data remains unknown. This paper compares the quality of full-line grocery store information from Yelp, a crowdsourced content service, to a "ground truth" data set (Detroit Food Map) and a commercially-available dataset (Reference USA) for the greater Detroit area. Results suggest that Yelp is more accurate than Reference USA in identifying healthy food stores in urban areas. Researchers investigating the relationship between the nutrition environment and health may consider Yelp as a reliable and valid source for identifying sources of healthy food in urban environments.
Hair Testing for Drugs of Abuse and New Psychoactive Substances in a High-Risk Population.
Salomone, Alberto; Palamar, Joseph J; Gerace, Enrico; Di Corcia, Daniele; Vincenti, Marco
2017-06-01
Hundreds of new psychoactive substances (NPS) have emerged in the drug market over the last decade. Few drug surveys in the USA, however, ask about use of NPS, so prevalence and correlates of use are largely unknown. A large portion of NPS use is unintentional or unknown as NPS are common adulterants in drugs like ecstasy/Molly, and most NPS are rapidly eliminated from the body, limiting efficacy of urine, blood and saliva testing. We utilized a novel method of examining prevalence of NPS use in a high-risk population utilizing hair-testing. Hair samples from high-risk nightclub and dance music attendees were tested for 82 drugs and metabolites (including NPS) using ultra-high performance liquid chromatography-tandem mass spectrometry. Eighty samples collected from different parts of the body were analyzed, 57 of which detected positive for at least one substance-either a traditional or new drug. Among these, 26 samples tested positive for at least one NPS-the most common being butylone (25 samples). Other new drugs detected include methylone, methoxetamine, 5/6-APB, α-PVP and 4-FA. Hair analysis proved a powerful tool to gain objective biological drug-prevalence information, free from possible biases of unintentional or unknown intake and untruthful reporting of use. Such testing can be used actively or retrospectively to validate survey responses and inform research on consumption patterns, including intentional and unknown use, polydrug-use, occasional NPS intake and frequent or heavy use. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Epizootic podoknemidokoptiasis in American robins
Pence, Danny B.; Cole, Rebecca A.; Brugger, Kristin E.; Fischer, John R.
1999-01-01
Epizootics of scaly leg disease caused by infection with the submacroscopic mite Knemidokoptes jamaicensis (Acari: Knemidokoptidae) in migratory American robins (Turdus migratorius) from a residential area of Tulsa (Oklahoma, USA) are documented during the winters (December through February) of 1993–94 and 1994–95. Estimates of 60 to >80% of the birds in several different flights arriving in the area had lesions consistent with knemidokoptic mange. Epizootic occurrence of K. jamaicensis also is confirmed incidentally in American robins from Georgia (USA) in 1995 and 1998 and in Florida (USA) in 1991. These are the first confirmed epizootics of scaly leg attributed to infections with mites specifically identified as K. jamaicensis in North America. Severity of observed lesions in American robins ranged from scaly hyperkeratosis of the feet and legs to extensive proliferative lesions with loss of digits or the entire foot in some birds. Histologically, there was severe diffuse hyperkeratosis of the epidermis which contained numerous mites and multifocal aggregates of degranulating to degenerating eosinophilic heterophils; there was mild to severe superficial dermatitis with aggregates of eosinophilic heterophils and some mononuclear cells. Based on limited data from affected captive birds in Florida, we questioned the efficacy of ivermectin as an effective acaricide for knemidokoptiasis and propose that conditions associated with captivity may exacerbate transmission of this mite among caged birds. While knemidokoptic mange apparently can result in substantial host morbidity and possibly mortality, the ultimate impact of these epizootics on American robin populations presently is unknown.
NASA Astrophysics Data System (ADS)
Sohn, D.; Park, K.
2012-12-01
The increased amount of saturated water vapor due to the Earth's temperature rise frequently causes abnormal meteorological phenomena such as local severe rainfall in Korea. The National Institute of Meteorological Research of Korea Meteorological Administration (KMA) conducted observation experiments using a variety of water-vapor measuring equipments to improve the accuracy of weather forecasts and accurately measure the precipitable water vapor in the atmosphere. Equipments used were GNSS, water vapor radiometers (WVR), radiosonde, and LiDAR. For GNSS measurements we used two receivers that can collect not only GPS but also GLONASS signals: Trimble NetR5 and Septentrio PolaRx4. The two WVR makers are Raidometrics and RPG. For radiosonde observations, KMA launched Vaisala GPSondes every 6 hours during the experiment period. The LiDAR system was made locally by Hanbat University in Daejeon. Thus, we could obtain collocation experiment results from 6 different kinds of water vapor measurement and analyze the characteristics of each device.
Dailey, M; Ellin, R; Parás, A
2005-06-01
A new species of digenetic trematode and 2 species of ectoparasites from Zalophus wollebaeki Silvertsen, 1953 (Carnivora: Otariidae) in the Galapagos Islands, Ecuador, are reported. These include an eye fluke of Philophthalmus Looss, 1899 (Echinostomata: Philophthalmidae) as well as, to our knowledge, the first report of Antarctophthirus microchir (Trouessart and Neumann, 1888) Enderlein, 1906 (Arthropoda: Anoplura) and Orthohalarachne diminuata (Doetschman, 1944) Newell, 1947 (Arthropoda: Acarina) from this host and location. Philophthalmus zalophi n. sp. differs from the 4 other marine species of Philophthalmus (P. andersoni Dronen and Penner, 1975; P. burrili Howell and Bearup, 1967; P. hegeneri Penner and Fried, 1963; and P. larsoni Penner and Trimble, 1970) by its mammalian host, large body size, lack of tegumental spines, posterior length of seminal vesicle, placement of genital pore, size ratio of oral sucker to acetabulum, shape and size of testes, and size ratio of ovary to testis.
Suleiman, Ramzi
2002-12-01
The author investigated how Palestinian (n = 130) and Jewish (n = 153) Israeli university students perceived the collective identity of the Palestinian minority in Israel. The Palestinian and Jewish respondents perceived the "identity space" of the minority as linear, or bipolar, with 1 pole defined by the national (Palestinian) identity and the other defined by the civic (Israeli) label. The Palestinian respondents defined their collective identity in national (Palestinian, Arab) and integrative (Israeli-Palestinian) terms; the Jewish respondents perceived the minority's identity as integrative (Israeli-Palestinian). Different political outlooks among Palestinian respondents were related to their identification with the civic (Israeli) identity but not to their identification with the national (Palestinian) identity. In contrast, different political outlooks among Jewish respondents were related to their inclusion, or exclusion, of the national (Palestinian) component in their definition of the minority's identity. Implications of the results are discussed in terms of a minority acculturation model (J. Berry, J. Trimble, & E. Olmedo, 1986).
AUGUSTO'S Sundial: Image-Based Modeling for Reverse Engeneering Purposes
NASA Astrophysics Data System (ADS)
Baiocchi, V.; Barbarella, M.; Del Pizzo, S.; Giannone, F.; Troisi, S.; Piccaro, C.; Marcantonio, D.
2017-02-01
A photogrammetric survey of a unique archaeological site is reported in this paper. The survey was performed using both a panoramic image-based solution and by classical procedure. The panoramic image-based solution was carried out employing a commercial solution: the Trimble V10 Imaging Rover (IR). Such instrument is an integrated cameras system that captures 360 degrees digital panoramas, composed of 12 images, with a single push. The direct comparison of the point clouds obtained with traditional photogrammetric procedure and V10 stations, using the same GCP coordinates has been carried out in Cloud Compare, open source software that can provide the comparison between two point clouds supplied by all the main statistical data. The site is a portion of the dial plate of the "Horologium Augusti" inaugurated in 9 B.C.E. in the area of Campo Marzio and still present intact in the same position, in a cellar of a building in Rome, around 7 meter below the present ground level.
Petrescu, Dragos C; Hollands, Gareth J; Couturier, Dominique-Laurent; Ng, Yin-Lam; Marteau, Theresa M
2016-01-01
"Nudging"-modifying environments to change people's behavior, often without their conscious awareness-can improve health, but public acceptability of nudging is largely unknown. We compared acceptability, in the United Kingdom (UK) and the United States of America (USA), of government interventions to reduce consumption of sugar-sweetened beverages. Three nudge interventions were assessed: i. reducing portion Size, ii. changing the Shape of the drink containers, iii. changing their shelf Location; alongside two traditional interventions: iv. Taxation and v. Education. We also tested the hypothesis that describing interventions as working through non-conscious processes decreases their acceptability. Predictors of acceptability, including perceived intervention effectiveness, were also assessed. Participants (n = 1093 UK and n = 1082 USA) received a description of each of the five interventions which varied, by randomisation, in how the interventions were said to affect behaviour: (a) via conscious processes; (b) via non-conscious processes; or (c) no process stated. Acceptability was derived from responses to three items. Levels of acceptability for four of the five interventions did not differ significantly between the UK and US samples; reducing portion size was less accepted by the US sample. Within each country, Education was rated as most acceptable and Taxation the least, with the three nudge-type interventions rated between these. There was no evidence to support the study hypothesis: i.e. stating that interventions worked via non-conscious processes did not decrease their acceptability in either the UK or US samples. Perceived effectiveness was the strongest predictor of acceptability for all interventions across the two samples. In conclusion, nudge interventions to reduce consumption of sugar-sweetened beverages seem similarly acceptable in the UK and USA, being more acceptable than taxation, but less acceptable than education. Contrary to prediction, we found no evidence that highlighting the non-conscious processes by which nudge interventions may work decreases their acceptability. However, highlighting the effectiveness of all interventions has the potential to increase their acceptability.
Salgado-Pabon, Wilmara; Meyerholz, David K.; White, Mark J.; Schlievert, Patrick M.
2016-01-01
ABSTRACT The Spl proteases are a group of six serine proteases that are encoded on the νSaβ pathogenicity island and are unique to Staphylococcus aureus. Despite their interesting biochemistry, their biological substrates and functions in virulence have been difficult to elucidate. We found that an spl operon mutant of the community-associated methicillin-resistant S. aureus USA300 strain LAC induced localized lung damage in a rabbit model of pneumonia, characterized by bronchopneumonia observed histologically. Disease in the mutant-infected rabbits was restricted in distribution compared to that in wild-type USA300-infected rabbits. We also found that SplA is able to cleave the mucin 16 glycoprotein from the surface of the CalU-3 lung cell line, suggesting a possible mechanism for wild-type USA300 spreading pneumonia to both lungs. Investigation of the secreted and surface proteomes of wild-type USA300 and the spl mutant revealed multiple alterations in metabolic proteins and virulence factors. This study demonstrates that the Spls modulate S. aureus physiology and virulence, identifies a human target of SplA, and suggests potential S. aureus targets of the Spl proteases. IMPORTANCE Staphylococcus aureus is a versatile human pathogen that produces an array of virulence factors, including several proteases. Of these, six proteases called the Spls are the least characterized. Previous evidence suggests that the Spls are expressed during human infection; however, their function is unknown. Our study shows that the Spls are required for S. aureus to cause disseminated lung damage during pneumonia. Further, we present the first example of a human protein cut by an Spl protease. Although the Spls were predicted not to cut staphylococcal proteins, we also show that an spl mutant has altered abundance of both secreted and surface-associated proteins. This work provides novel insight into the function of Spls during infection and their potential ability to degrade both staphylococcal and human proteins. PMID:27747296
Johnson, A J; Shukle, R H; Chen, M-S; Srivastava, S; Subramanyam, S; Schemerhorn, B J; Weintraub, P G; Abdel Moniem, H E M; Flanders, K L; Buntin, G D; Williams, C E
2015-01-01
Evidence is emerging that some proteins secreted by gall-forming parasites of plants act as effectors responsible for systemic changes in the host plant, such as galling and nutrient tissue formation. A large number of secreted salivary gland proteins (SSGPs) that are the putative effectors responsible for the physiological changes elicited in susceptible seedling wheat by Hessian fly, Mayetiola destructor (Say), larvae have been documented. However, how the genes encoding these candidate effectors might respond under field conditions is unknown. The goal of this study was to use microarray analysis to investigate variation in SSGP transcript abundance amongst field collections from different geographical regions (southeastern USA, central USA, and the Middle East). Results revealed significant variation in SSGP transcript abundance amongst the field collections studied. The field collections separated into three distinct groups that corresponded to the wheat classes grown in the different geographical regions as well as to recently described Hessian fly populations. These data support previous reports correlating Hessian fly population structure with micropopulation differences owing to agro-ecosystem parameters such as cultivation of regionally adapted wheat varieties, deployment of resistance genes and variation in climatic conditions. PMID:25528896
NASA Technical Reports Server (NTRS)
Himwich, Ed; Strand, Richard
2013-01-01
This report includes an assessment of the network performance in terms of lost observing time for the 2012 calendar year. Overall, the observing time loss was about 12.3%, which is in-line with previous years. A table of relative incidence of problems with various subsystems is presented. The most significant identified causes of loss were electronics rack problems (accounting for about 21.8% of losses), antenna reliability (18.1%), RFI (11.8%), and receiver problems (11.7%). About 14.2% of the losses occurred for unknown reasons. New antennas are under development in the USA, Germany, and Spain. There are plans for new telescopes in Norway and Sweden. Other activities of the Network Coordinator are summarized.
The plumbing of Old Faithful Geyser revealed by hydrothermal tremor
NASA Astrophysics Data System (ADS)
Vandemeulebrouck, J.; Roux, P.; Cros, E.
2013-05-01
Faithful Geyser in Yellowstone National Park (USA) has attracted numerous scientific investigations for over two centuries to better understand its geological structure, the physics of its eruptions, and the controls of its intermittency. Using data acquired with a seismic array in 1992, we track the sources of hydrothermal tremor produced by boiling and cavitation inside the geyser. The location of seismic sources identifies a previously unknown lateral cavity at 15 m below the surface, on the SW side of the vent, and connected to the conduit. This reservoir is activated at the beginning of each geyser eruption cycle and plays a major role in the oscillatory behavior of the water level in the conduit before each eruption.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Senft, D.
1986-02-01
Cuphea, a relatively unknown plant outside the scientific community, might someday provide valuable oils for manufacturing soaps, detergents, surfactants, and lubricants, and may have medical, nutritional and dietetic applications as well. Unique properties of oils found in its seed make cuphea a potentially valuable new crop for the USA. Its seeds contain large quantities of medium-chain fatty acids such as lauric acid, which is used in manufacturing soaps and detergents. Other medium-chain fatty acids in cuphea can be used for clinical treatment of rare human ailments associated with fat absorption. New uses for the fatty acids in the seed maymore » be developed and economic conditions may change, making the crop more or less valuable.« less
A new AMS facility in Caserta/Italy
NASA Astrophysics Data System (ADS)
Terrasi, F.; Rogalla, D.; De Cesare, N.; D'Onofrio, A.; Lubritto, C.; Marzaioli, F.; Passariello, I.; Rubino, M.; Sabbarese, C.; Casa, G.; Palmieri, A.; Gialanella, L.; Imbriani, G.; Roca, V.; Romano, M.; Sundquist, M.; Loger, R.
2007-06-01
A new AMS system has been installed at Center for Isotopic Research on Cultural and Environmental Heritage (CIRCE) in Caserta/Italy. It was built by National Electrostatics Corp. Middleton, WI/USA, and arrived at CIRCE in the middle of January 2005; the installation and the acceptance tests were completed at the end of February 2005. At first, the system is intended for Radiocarbon AMS; for future Al and Be AMS only minor upgrades are needed and the magnets are designed to bend heavy isotopes like Uranium. Concerning Radiocarbon AMS, the first measurements of unknown samples, prepared in the internal preparation laboratory, already yielded results of high precision and 14C dating is in full swing.
Are bison exotic in the Wrangell-St. Elias National Park and Preserve?
NASA Astrophysics Data System (ADS)
Peek, James M.; Miquelle, Dale G.; Wright, R. Gerald
1987-03-01
The effect of past distributions of animal populations now extinct in an area from unknown causes is considered relative to their status as exotic or native in national parks. The example is the bison (Bison bison) on the Copper and Chitina river drainages in Alaska in the USA which was introduced prior to establishment of Wrangell-St. Elias National Park and Preserve. The fossil record suggests that bison were present as recently as 500 years ago in Alaska. The policy of the US National Park Service to maintain natural ecosystems and restrict or eliminate exotic species raises the issue of whether this species should be treated as exotic or native.
Soper, Nathaniel J
2011-08-01
This article reviews the current literature pertaining to the diagnosis and management of gastroesophageal reflux disease (GERD) and hiatal hernia. GERD is one of the most common gastrointestinal disorders in the USA. For effective management, a conclusive diagnosis must be made. Most patients are effectively managed by acid suppression therapy, whereas others require procedural treatment. Endoluminal treatment of GERD is an option, but long-term results of this therapy are unknown. The "gold standard" surgical treatment of GERD is laparoscopic Nissen fundoplication. Large hiatal hernias are difficult to manage with a relatively high rate of recurrent hiatal hernia. Whether or not to use mesh at the hiatus to decrease this occurrence is currently debatable.
NASA Astrophysics Data System (ADS)
Zimakov, Leonid; Jackson, Michael; Passmore, Paul; Raczka, Jared; Alvarez, Marcos; Barrientos, Sergio
2015-04-01
We will discuss and show the results obtained from an integrated SeismoGeodetic System, model SG160-09, installed in the Chilean National Network. The SG160-09 provides the user high rate GNSS and accelerometer data, full epoch-by-epoch measurement integrity and, using the Trimble Pivot™ SeismoGeodetic App, the ability to create combined GNSS and accelerometer high-rate (200Hz) displacement time series in real-time. The SG160-09 combines seismic recording with GNSS geodetic measurement in a single compact, ruggedized package. The system includes a low-power, 220-channel GNSS receiver powered by the latest Trimble-precise Maxwell™6 technology and supports tracking GPS, GLONASS and Galileo signals. The receiver incorporates on-board GNSS point positioning using Real-Time Precise Point Positioning (PPP) technology with satellite clock and orbit corrections delivered over IP networks. The seismic recording element includes an ANSS Class A, force balance triaxial accelerometer with the latest, low power, 24-bit A/D converter, which produces high-resolution seismic data. The SG160-09 processor acquires and packetizes both seismic and geodetic data and transmits it to the central station using an advanced, error-correction protocol with back fill capability providing data integrity between the field and the processing center. The SG160-09 has been installed in the seismic station close to the area of the Iquique earthquake of April 1, 2014, in northern Chile, a seismically prone area at the current time. The hardware includes the SG160-09 system, external Zephyr Geodetic-2 GNSS antenna, and high-speed Internet communication media. Both acceleration and displacement data was transmitted in real-time to the National Seismological Center in Santiago for real-time data processing using Earthworm / Early Bird software. Command/Control of the field station and real-time GNSS position correction are provided via the Pivot software suite. Data from the SG160-09 system was used for seismic event characterization along with data from traditional stand-alone broadband seismic and geodetic stations installed in the network. Our presentation will focus on the key improvements of the network installation with the SG160-09 system, rapid data transmission, and real-time data processing for strong seismic events and aftershock characterization as well as advanced features of the SG160-09 for Earthquake and Tsunami Early Warning system.
Chatham-Stephens, Kevin; Taylor, Ethel; Chang, Arthur; Peterson, Amy; Daniel, Johnni; Martin, Colleen; Deuster, Patricia; Noe, Rebecca; Kieszak, Stephanie; Schier, Josh; Klontz, Karl; Lewis, Lauren
2017-01-01
In September 2013, the Hawaii Department of Health (HDOH) was notified of seven adults who developed acute hepatitis after taking OxyELITE Pro™, a weight loss and sports dietary supplement. CDC assisted HDOH with their investigation, then conducted case-finding outside of Hawaii with FDA and the Department of Defense (DoD). We defined cases as acute hepatitis of unknown etiology that occurred from April 1, 2013, through December 5, 2013, following exposure to a weight loss or muscle-building dietary supplement, such as OxyELITE Pro™. We conducted case-finding through multiple sources, including data from poison centers (National Poison Data System [NPDS]) and FDA MedWatch. We identified 40 case-patients in 23 states and two military bases with acute hepatitis of unknown etiology and exposure to a weight loss or muscle building dietary supplement. Of 35 case-patients who reported their race, 15 (42.9%) reported white and 9 (25.7%) reported Asian. Commonly reported symptoms included jaundice, fatigue, and dark urine. Twenty-five (62.5%) case-patients reported taking OxyELITE Pro™. Of these 25 patients, 17 of 22 (77.3%) with available data were hospitalized and 1 received a liver transplant. NPDS and FDA MedWatch each captured seven (17.5%) case-patients. Improving the ability to search surveillance systems like NPDS and FDA MedWatch for individual and grouped dietary supplements, as well as coordinating case-finding with DoD, may benefit ongoing surveillance efforts and future outbreak responses involving adverse health effects from dietary supplements. This investigation highlights opportunities and challenges in using multiple sources to identify cases of suspected supplement associated adverse events. Published 2016. This article is a U.S. Government work and is in the public domain in the USA. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.
Castelblanco, Rodrigo Lopez; Lee, MinJae; Hasbun, Rodrigo
2014-09-01
Bacterial meningitis continues to be a substantial cause of morbidity and mortality, but the epidemiological trends after adjunctive dexamethasone recommendations are unknown in the USA. We aimed to describe the changing patterns among the most common bacterial causes in the USA after conjugate vaccination and to assess the association between adjunctive dexamethasone and mortality. For this population-based observational study, we searched information available from hospital discharges about incidence and inpatient mortality for the most important causes of community and nosocomial bacterial meningitis based on International Classification of Diseases coding across all hospitals in the USA between 1997 and 2010 with the HealthCare Cost Utilization Project (HCUP) network database. We calculated incidences according to US Census Bureau data and used a negative binomial regression model to evaluate the significance of changes over time. We assessed mortality from pneumococcus for three periods 1997-2001 (baseline), 2002-04 (transition years), and 2005-08 (after corticosteroid recommendations were available). Streptococcus pneumoniae incidence fell from 0·8 per 100 000 people in 1997, to 0·3 per 100 000 people by the end of 2010 (RR 0·3737, 95% CI 0·1825-0·7656). Mortality from pneumococcal meningitis decreased between 2005 (0·049 per 100 000 people) and 2008 (0·024 per 100 000 people) compared with between 2002 (0·073 per 100 000 people) and 2004 (0·063 per 100 000 people; RR 0·5720, 95% CI 0·4303-0·7582). The incidence of Neisseria meningitidis infection decreased from 0·721 per 100 000 people in 1997, to 0·123 per 100 000 people in 2010 (RR 0·1386, 95% CI 0·048-0·4284), which has placed this pathogen close to common bacterial causes of nosocomial meningitis such as staphylococcus and Gram-negative bacteria and to Haemophilus influenzae. S pneumoniae continues to be the leading identifiable cause of bacterial meningitis in the USA, but with a significant decrease in incidence and mortality associated with the introduction of conjugated vaccines and a mortality decrease that is associated with the introduction of recommendations for use of adjunctive dexamethasone for pneumococcal meningitis. National Center for Research Resources. Copyright © 2014 Elsevier Ltd. All rights reserved.
Epididymitis Caused by Brucella ovis in a Southern Ontario Sheep Flock
Buckrell, Brian C.; McEwen, Scott A.; Johnson, Walter H.; Savage, Neale C.
1985-01-01
Epididymitis was diagnosed in three rams in a commercial sheep flock in southern Ontario. The affected rams had palpably enlarged epididymides and two rams had semen which contained inflammatory cells and was of poor quality. Serum compliment fixation titers for Brucella ovis were 1:20, 1:80 and 1:90. Five other rams in the flock were clinically normal and without titers. Two of the affected rams had lesions similar to those produced by experimental infection with B. ovis. The infection in the rams had no apparent affect on ewe performance. The source of the infection remains unknown, but the rams were purchased from a flock which had imported ewes from the western U.S.A. ImagesFigure 1.Figure 2. PMID:17422577
Turchetti, Benedetta; Selbmann, Laura; Blanchette, Robert A; Di Mauro, Simone; Marchegiani, Elisabetta; Zucconi, Laura; Arenz, Brett E; Buzzini, Pietro
2015-01-01
Twenty yeast strains, representing a selection from a wider group of more than 60 isolates were isolated from cold environments worldwide (Antarctica, Iceland, Russia, USA, Italian and French Alps, Apennines). The strains were grouped based on their common morphological and physiological characteristics. A phylogeny based on D1/D2 ribosomal DNA sequences placed them in an intermediate position between Cryptococcus saitoi and Cryptococcus friedmannii; the ITS1 and ITS2 rDNA phylogeny demonstrated that these strains belong to two related but hitherto unknown species within the order Filobasidiales, albidus clade. These two novel species are described with the names Cryptococcus vaughanmartiniae (type strain DBVPG 4736(T)) and Cryptococcus onofrii (type strain DBVPG 5303(T)).
In ecoregions across western USA streamflow increases during post-wildfire recovery
NASA Astrophysics Data System (ADS)
Wine, Michael L.; Cadol, Daniel; Makhnin, Oleg
2018-01-01
Continued growth of the human population on Earth will increase pressure on already stressed terrestrial water resources required for drinking water, agriculture, and industry. This stress demands improved understanding of critical controls on water resource availability, particularly in water-limited regions. Mechanistic predictions of future water resource availability are needed because non-stationary conditions exist in the form of changing climatic conditions, land management paradigms, and ecological disturbance regimes. While historically ecological disturbances have been small and could be neglected relative to climatic effects, evidence is accumulating that ecological disturbances, particularly wildfire, can increase regional water availability. However, wildfire hydrologic impacts are typically estimated locally and at small spatial scales, via disparate measurement methods and analysis techniques, and outside the context of climate change projections. Consequently, the relative importance of climate change driven versus wildfire driven impacts on streamflow remains unknown across the western USA. Here we show that considering wildfire in modeling streamflow significantly improves model predictions. Mixed effects modeling attributed 2%-14% of long-term annual streamflow to wildfire effects. The importance of this wildfire-linked streamflow relative to predicted climate change-induced streamflow reductions ranged from 20%-370% of the streamflow decrease predicted to occur by 2050. The rate of post-wildfire vegetation recovery and the proportion of watershed area burned controlled the wildfire effect. Our results demonstrate that in large areas of the western USA affected by wildfire, regional predictions of future water availability are subject to greater structural uncertainty than previously thought. These results suggest that future streamflows may be underestimated in areas affected by increased prevalence of hydrologically relevant ecological disturbances such as wildfire.
Foust-Wheatcraft, Desirae A; Dell, Darin L; Rosenkrantz, Wayne S; Griffin, Craig E
2017-12-01
The intradermal irritant threshold concentration for many allergens is unknown. To determine the intradermal irritant threshold concentration (ITC) of nine allergens from two different manufacturers. Twenty privately owned clinically nonallergic dogs. Alternaria, cat dander, Dermatophagoides farinae, Chenopodium album (lamb's quarter), Xanthium strumarium (cocklebur), Prosopis glandulosa (mesquite), Morus alba (white mulberry), Cynodon dactylon (Bermuda grass) and Phleum pretense (Timothy grass) from two manufacturers (ALK; Round Rock, TX, USA and Greer ® Laboratories; Lenoir, NC, USA) were injected intradermally at two dilutions and at 15 and 30 min evaluated subjectively (1-4) and objectively (horizontal wheal diameter) by two blinded investigators. A subjective score of 3 or 4 by either investigator at either timed reading was considered positive. If both concentrations resulted in positive reactions, two additional dilutions were performed. The ITC was defined as the lowest tested concentration that elicited a positive reaction in ≥10% of animals. The ITCs were Alternaria >2,000 PNU/mL; cat dander 750 PNU/mL (ALK) and 2,000 PNU/mL (Greer ® ); D. farinae <1:10,000 w/v; C. album <6,000 PNU/mL; X. strumarium <6,000 PNU/mL; P. glandulosa <500 PNU/mL; M. alba <6,000 PNU/mL; C. dactylon <10,000 PNU/mL (ALK) and <6,000 PNU/mL (Greer ® ); and P. pretense <6,000 PNU/mL. There were significant differences in subjective scoring and objective measurement between manufacturers for Alternaria, cat dander and P. pretense. Results revealed significant positive correlation between subjective scoring and objective measurement for each time, investigator and manufacturer separately. © 2017 ESVD and ACVD.
Pornsukarom, S; Patchanee, P; Erdman, M; Cray, P F; Wittum, T; Lee, J; Gebreyes, W A
2015-03-01
Salmonella enterica serovar Rissen has been recognized as one of the most common serovar among humans and pork production systems in different parts of the world, especially Asia. In the United States, this serovar caused outbreaks but its epidemiologic significance remains unknown. The objectives of this study were to compare the phenotypic (antimicrobial susceptibility) and genotypic attributes of Salmonella Rissen isolated in Thailand (Thai) and the United States (US). All the Thai isolates (n = 30) were recovered from swine faecal samples. The US isolates (n = 35) were recovered from swine faecal samples (n = 29), cattle (n = 2), chicken (n = 2), dog (n = 1) and a ready-to-eat product (n = 1). The antimicrobial susceptibility of isolates was determined using the Kirby-Bauer disk diffusion method with a panel of 12 antimicrobials. Pulse-field gel electrophoresis (PFGE) was used to determine the genotypic diversity of isolates. All Thai isolates showed multidrug resistance (MDR) with the most frequent antibiotic resistance shown against ampicillin (100%), sulfisoxazole (96.7%), tetracycline (93.3%), streptomycin (90%) and chloramphenicol (30%). About half of the isolates of USA origin were pan-susceptible and roughly 30% were resistant to only tetracycline (R-type: Te). Salmonella Rissen isolated from Thailand and the USA in this study were found to be clonally unrelated. Genotypic analyses indicated that isolates were clustered primarily based on the geographic origin implying the limited clonality among the strains. Clonal relatedness among different host species within the same geography (USA) was found. We found genotypic similarity in Thai and US isolates in few instances but with no epidemiological link. Further studies to assess propensity for increased inter-regional transmission and dissemination is warranted. © 2014 Blackwell Verlag GmbH.
Snus use and rejection in the USA.
Biener, Lois; Roman, Anthony M; Mc Inerney, Scott A; Bolcic-Jankovic, Dragana; Hatsukami, Dororthy K; Loukas, Alexandra; O'Connor, Richard J; Romito, Laura
2016-07-01
To determine whether snus might become a strategy for reducing the harm associated with cigarette smoking in the USA as appears to be the case in Sweden, we examined receptivity to snus use in two cities with the greatest exposure to the major brands. A dual frame, telephone survey and a brief mail survey were conducted in 2011 and 2012 in Indianapolis, Indiana and Dallas/Fort Worth Texas. Over 5000 adults completed surveys. Trial, ever use, current use and reasons for using or quitting snus after trial were measured. Among male smokers, 29.9% had ever tried snus (CI 22.7 to 38.1) and 4.2% were current users (CI 1.6 to 10.7). Among female smokers, 8.5% ever tried snus (CI 4.4 to 15.7) and current use was unknown. Current use was virtually absent among former smokers and never smokers. A major predictor of any level of snus use was current use of conventional smokeless tobacco. Those who tried and gave up snus cited curiosity (41.3%) and the fact that it was available at low or no cost (30%) as reasons for trial; reasons for not continuing included preferring another form of tobacco (75.1%) and disliking the mouth feel (34.6%). Almost all current snus users indicated that they were trying to cut down on cigarettes, but few (3.9%) were using it to quit smoking entirely. The low rate of adoption of snus suggests that neither the hopes nor the fears surrounding this new product are likely to be realised in the USA with the current marketing patterns. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
Hair of the dog: obtaining samples from coyotes and wolves noninvasively
Ausband, David E.; Young, Julie; Fannin, Barbara; Mitchell, Michael S.; Stenglein, Jennifer L.; Waits, Lisette P.; Shivik, John A.
2011-01-01
Canids can be difficult to detect and their populations difficult to monitor. We tested whether hair samples could be collected from coyotes (Canis latrans) in Texas, USA and gray wolves (C. lupus) in Montana, USA using lure to elicit rubbing behavior at both man-made and natural collection devices. We used mitochondrial and nuclear DNA to determine whether collected hair samples were from coyote, wolf, or nontarget species. Both coyotes and wolves rubbed on man-made barbed surfaces but coyotes in Texas seldom rubbed on hanging barbed surfaces. Wolves in Montana showed a tendency to rub at stations where natural-material collection devices (sticks and debris) were present. Time to detection was relatively short (5 nights and 4 nights for coyotes and wolves, respectively) with nontarget and unknown species comprising approximately 26% of the detections in both locations. Eliciting rubbing behavior from coyotes and wolves using lures has advantages over opportunistic genetic sampling methods (e.g., scat transects) because it elicits a behavior that deposits a hair sample at a fixed sampling location, thereby increasing the efficiency of sampling for these canids. Hair samples from rub stations could be used to provide estimates of abundance, measures of genetic diversity and health, and detection-nondetection data useful for cost-effective population monitoring.
Wüsten, Caroline; Lincoln, Tania M
2017-07-01
For decades, researchers have attributed the better prognosis of psychosis in developing countries to a host of socio-cultural factors, including family functioning. Nevertheless, it is unknown whether family functioning and its association with symptoms differ across countries. This study assessed family functioning (support, satisfaction with family relations, and criticism) and psychosis proneness in community samples from Chile (n =399), Colombia (n=486), Indonesia (n=115), Germany (n=174) and the USA (n=143). Family functioning was compared between prototypical developing countries (Chile, Columbia, Indonesia) and highly industrialized countries (Germany, USA). Hierarchical regression analysis was used to test for the moderating effect of country on the associations between family functioning and psychosis proneness. Participants from developing countries perceived more support and felt more satisfied. However, they also perceived more criticism than participants from highly industrialized countries. Criticism and family satisfaction were significantly associated with psychosis proneness. Moreover, the relationship between criticism and psychosis proneness was significantly stronger in developing countries compared to highly industrialized countries. Generally, family satisfaction and criticism appear to be more relevant to psychosis proneness than the quantity of family support. Moreover, criticism seems to be more closely related to psychosis proneness in developing countries. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.
Wilbur, Ami E; Ford, Susan E; Gauthier, Julie D; Gomez-Chiarri, Marta
2012-12-27
The continuing challenges to the management of both wild and cultured eastern oyster Crassostrea virginica populations resulting from protozoan parasites has stimulated interest in the development of molecular assays for their detection and quantification. For Haplosporidium nelsoni, the causative agent of multinucleated sphere unknown (MSX) disease, diagnostic evaluations depend extensively on traditional but laborious histological approaches and more recently on rapid and sensitive (but not quantitative) end-point polymerase chain reaction (PCR) assays. Here, we describe the development and application of a quantitative PCR (qPCR) assay for H. nelsoni using an Applied Biosystems TaqMan® assay designed with minor groove binder (MGB) probes. The assay was highly sensitive, detecting as few as 20 copies of cloned target DNA. Histologically evaluated parasite density was significantly correlated with the quantification cycle (Cq), regardless of whether quantification was categorical (r2 = 0.696, p < 0.0001) or quantitative (r2 = 0.797, p < 0.0001). Application in field studies conducted in North Carolina, USA (7 locations), revealed widespread occurrence of the parasite with moderate to high intensities noted in some locations. In Rhode Island, USA, application of the assay on oysters from 2 locations resulted in no positives.
CHAUDHARI, AJIT M. W.; JAMISON, STEVEN T.; MCNALLY, MICHAEL P.; PAN, XUELIANG; SCHMITT, LAURA C.
2014-01-01
Athletes at high risk of groin strains in sports such as hockey and soccer often choose to wear shorts with directional compression to aid in prevention or recovery from hip adductor strains. Large eccentric contractions are known to result in or exacerbate strain injuries, but it is unknown if these shorts have a beneficial effect on hip adductor muscle activity. In this study, surface electromyography of the adductor longus and ground reaction force (GRF) data were obtained simultaneously on 29 healthy individuals without previous history of serious injury while performing unanticipated 45° run-to-cut maneuvers in a laboratory setting wearing shorts with non-directional compression (control, HeatGear, Under Armour, USA) or shorts with directional compression (directional, CoreShort PRO, Under Armour, USA), in random order. Average adductor activity in the stance leg was significantly lower in the directional condition than in the control condition during all parts of stance phase (all p<0.042). From this preliminary analysis, wearing directional compression shorts appears to be associated with reduced stance limb hip adductor activity. Athletes seeking to reduce demand on the hip adductors as they approach full return to activities may benefit from the use of directional compression shorts. PMID:24669858
Chaudhari, Ajit M W; Jamison, Steven T; McNally, Michael P; Pan, Xueliang; Schmitt, Laura C
2014-01-01
Athletes at high risk of groin strains in sports such as hockey and soccer often choose to wear shorts with directional compression to aid in prevention of or recovery from hip adductor strains. Large, eccentric contractions are known to result in or exacerbate strain injuries, but it is unknown if these shorts have a beneficial effect on hip adductor muscle activity. In this study, surface electromyography (EMG) of the adductor longus and ground reaction force (GRF) data were obtained simultaneously on 29 healthy individuals without previous history of serious injury while performing unanticipated 45° run-to-cut manoeuvres in a laboratory setting wearing shorts with non-directional compression (control, HeatGear, Under Armour, USA) or shorts with directional compression (directional, CoreShort PRO, Under Armour, USA), in random order. Average adductor activity in the stance leg was significantly lower in the directional condition than in the control condition during all parts of stance phase (all P < 0.042). From this preliminary analysis, wearing directional compression shorts appears to be associated with reduced stance limb hip adductor activity. Athletes seeking to reduce demand on the hip adductors as they approach full return to activities may benefit from the use of directional compression shorts.
Baseflow recession analysis across the Eagle Ford shale play (Texas, USA)
NASA Astrophysics Data System (ADS)
Arciniega, Saul; Brena-Naranjo, Agustin; Hernandez-Espriu, Jose Antonio; Pedrozo-Acuña, Adrian
2016-04-01
Baseflow is an important process of the hydrological cycle as it can be related to aquatic ecosystem health and groundwater recharge. The temporal and spatial dynamics of baseflow are typically governed by fluctuations in the water table of shallow aquifers hence groundwater pumping and return flow can greatly modify baseflow patterns. More recently, in some regions of the world the exploitation of gas trapped in shale formations by means of hydraulic fracturing (fracking) has raised major concerns on the quantitative and qualitative groundwater impacts. Although fracking implies massive amounts of groundwater withdrawals, its contribution on baseflow decline has not yet been fully investigated. Furthermore, its impact with respect to other human activities or climate extremes such as irrigation or extreme droughts, respectively, remain largely unknown. This work analyzes baseflow recession time-space patterns for a set of watersheds located across the largest shale producer in the world, the Eagle Ford shale play in Texas (USA). The period of study (1985-2014) includes a pre-development and post-development period. The dataset includes 56 hydrometric time series located inside and outside the shale play. Results show that during the development and expansion of the Eagle Ford play, around 70 % of the time series displayed a significant decline wheras no decline was observed during the pre-development)
NASA Astrophysics Data System (ADS)
Khlystov, A.; Subramanian, R.
2015-12-01
Secondary organic aerosol (SOA) from biogenic sources has a significant contribution to ambient aerosol loadings in Southeastern USA and thus contributes to adverse health effects of air pollution and influences regional and global climate. Volatility properties of biogenic SOA determine its concentration, reactivity, and lifetime, but are still largely unknown. As part of a larger study to assess the effect of biogenic SOA on aerosol optical properties, a set of instruments, including scanning mobility sizers (SMPS), single particle soot photometer (SP2), and a thermodenuder, was deployed during June 2015 at a Duke Forest site near Chapel Hill, NC. The site is characterized by a significant contribution of both biogenic and urban (mostly traffic) sources. Measurements of changes in aerosol volume and optical size upon heating in the thermodenuder at different temperatures are used to derive volatility properties of the ambient aerosol. A limited set of experiments was carried out using the tandem differential mobility analysis (TDMA) approach to investigate whether the ambient aerosol at the Duke Forest site is internally mixed with respect to its volatility properties. In this presentation we will discuss equilibrium and kinetic aspects of aerosol volatility observed during this study and implications of external vs. internal mixing for derivation of bulk volatility properties of ambient aerosol.
Lasier, Peter J.; Washington, John W.; Hassan, Sayed M.; Jenkins, Thomas M.
2011-01-01
Concentrations of perfluorinated chemicals (PFCs) were measured in surface waters and sediments from the Coosa River watershed in northwest Georgia, USA, to examine their distribution downstream of a suspected source. Samples from eight sites were analyzed using liquid chromatography-tandem mass spectrometry. Sediments were also used in 28-d exposures with the aquatic oligochaete, Lumbriculus variegatus, to assess PFC bioaccumulation. Concentrations of PFCs in surface waters and sediments increased significantly below a land-application site (LAS) of municipal/industrial wastewater and were further elevated by unknown sources downstream. Perfluorinated carboxylic acids (PFCAs) with eight or fewer carbons were the most prominent in surface waters. Those with 10 or more carbons predominated sediment and tissue samples. Perfluorooctane sulfonate (PFOS) was the major homolog in contaminated sediments and tissues. This pattern among sediment PFC concentrations was consistent among sites and reflected homolog concentrations emanating from the LAS. Concentrations of PFCs in oligochaete tissues revealed patterns similar to those observed in the respective sediments. The tendency to bioaccumulate increased with PFCA chain length and the presence of the sulfonate moiety. Biota-sediment accumulation factors indicated that short-chain PFCAs with fewer than seven carbons may be environmentally benign alternatives in aquatic ecosystems; however, sulfonates with four to seven carbons may be as likely to bioaccumulate as PFOS.
Ireland, Kylie B.; Hardy, Giles E. St. J.; Kriticos, Darren J.
2013-01-01
Phytophthora ramorum, an invasive plant pathogen of unknown origin, causes considerable and widespread damage in plant industries and natural ecosystems of the USA and Europe. Estimating the potential geographical range of P. ramorum has been complicated by a lack of biological and geographical data with which to calibrate climatic models. Previous attempts to do so, using either invaded range data or surrogate species approaches, have delivered varying results. A simulation model was developed using CLIMEX to estimate the global climate suitability patterns for establishment of P. ramorum. Growth requirements and stress response parameters were derived from ecophysiological laboratory observations and site-level transmission and disease factors related to climate data in the field. Geographical distribution data from the USA (California and Oregon) and Norway were reserved from model-fitting and used to validate the models. The model suggests that the invasion of P. ramorum in both North America and Europe is still in its infancy and that it is presently occupying a small fraction of its potential range. Phytophthora ramorum appears to be climatically suited to large areas of Africa, Australasia and South America, where it could cause biodiversity and economic losses in plant industries and natural ecosystems with susceptible hosts if introduced. PMID:23667628
The San Juan Canyon, southeastern Utah: A geographic and hydrographic reconnaissance
Miser, Hugh D.
1924-01-01
This report, which describes the San Juan Canyon, San Juan River and the tributary streams and the geography and to some extent the geology of the region, presents information obtained by me during the descent of the river with the Trimble party in 1921. The exploration of the canyon, which was financed jointly by the United States Geological Survey and the Southern California Edison Co., had as its primary object the mapping and study of the San Juan in connection with proposed power and storage projects along this and Colorado rivers.1 The exploration party was headed by K. W. Thimble, topographic engineer of the United States Geological Survey. Other members of the party were Robert N. Allen, Los Angeles, Calif., recorder; H. E. Blake, jr., Monticello, Utah, and Hugh Hyde, Salt Lake City, Utah, rodmen; Bert Loper, Green River, Utah, boatman; Heber Christensen, Moab, Utah, cook; and H. D. Miser, geologist. Wesley Oliver, of Mexican Hat, Utah, served as packer for the party and brought mail and provisions by pack train twice a month to specified accessible places west of Goodridge.
Peppler, Marie C.; Fitzpatrick, Faith A.
2005-01-01
Bank erosion is a natural process that occurs in meandering streams (Leopold and others, 1964); however, in the Midwestern United States, historical and present agricultural activities in uplands, riparian areas, and channels have increased erosion (Waters, 1995; Lyons and others, 2000; Simon and Rinaldi, 2000; and Knox, 2001). Reducing streambank erosion is important because sediment carried by streams has adverse environmental effects; for example, sediment carried by streams is a major source of phosphorus (Waters, 1995). Continuous cattle grazing in riparian areas may increase local erosion processes in a meandering stream by removal or trampling of bank vegetation, which in turn affects channel morphology, water chemistry, and fish and aquatic-insect habitat (Kauffman and Krueger, 1984; Fitch and Adams, 1998). However, studies of livestock exclusion from riparian corridors have shown mixed results in reducing bank erosion (Trimble, 1994; Sarr, 2002). Some studies have shown reduced bank erosion after row-cropped or continuously grazed riparian areas are converted to managed grazing (see inset box) (Lyons and others, 2000; Sovell and others, 2000; and Zaimes and others, 2004).
Use of NTRIP for optimizing the decoding algorithm for real-time data streams.
He, Zhanke; Tang, Wenda; Yang, Xuhai; Wang, Liming; Liu, Jihua
2014-10-10
As a network transmission protocol, Networked Transport of RTCM via Internet Protocol (NTRIP) is widely used in GPS and Global Orbiting Navigational Satellite System (GLONASS) Augmentation systems, such as Continuous Operational Reference System (CORS), Wide Area Augmentation System (WAAS) and Satellite Based Augmentation Systems (SBAS). With the deployment of BeiDou Navigation Satellite system(BDS) to serve the Asia-Pacific region, there are increasing needs for ground monitoring of the BeiDou Navigation Satellite system and the development of the high-precision real-time BeiDou products. This paper aims to optimize the decoding algorithm of NTRIP Client data streams and the user authentication strategies of the NTRIP Caster based on NTRIP. The proposed method greatly enhances the handling efficiency and significantly reduces the data transmission delay compared with the Federal Agency for Cartography and Geodesy (BKG) NTRIP. Meanwhile, a transcoding method is proposed to facilitate the data transformation from the BINary EXchange (BINEX) format to the RTCM format. The transformation scheme thus solves the problem of handing real-time data streams from Trimble receivers in the BeiDou Navigation Satellite System indigenously developed by China.
Hesselink, Gijs; Johnson, Julie; Batalden, Paul; Carlson, Michelle; Geense, Wytske; Groenewoud, Stef; Jones, Sylvester; Roy, Brita; Sansone, Christina; Wolf, Judith R L M; Bart, Bradley; Wollersheim, Hub
2017-09-07
The USA lags behind other high-income countries in many health indicators. Outcome differences are associated with differences in the relative spending between healthcare and social services at the national level. The impact of the ratio and delivery of social and healthcare services on the individual patient's health is however unknown. ' Reframing Healthcare Services through the Lens of Co-Production ' (RheLaunCh) will be a cross-Atlantic comparative study of the mechanisms by which healthcare and social service delivery may impact patient health with chronic conditions. Insight into these mechanisms is needed to better and cost-effectively organise healthcare and social services. We designed a mixed methods study to compare the socioeconomic background, needs of and service delivery to patients with congestive heart failure and chronic obstructive pulmonary disease in the USA and the Netherlands. We will conduct: (1) a literature scan to compare national and regional healthcare and social service systems; (2) a retrospective database study to compare patient's socioeconomic and clinical characteristics and the service use and spending at the national, regional and hospital level; (3) a survey to compare patient perceived quality of life, receipt and experience of service delivery and ability of these services to meet patient needs; and (4) multiple case studies to understand what patients need to better govern their quality of life and how needs are met by services. Ethics approval was granted by the ethics committee of the Radboud University Medical Center (2016-2423) in the Netherlands and by the Human Subjects Research Committee of the Hennepin Health Care System, Inc. (HSR #16-4230) in the USA. Multiple approaches will be used for dissemination of results, including (inter)national research presentations and peer-reviewed publications. A website will be established to support the development of a community of practice. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Hesselink, Gijs; Johnson, Julie; Batalden, Paul; Carlson, Michelle; Geense, Wytske; Groenewoud, Stef; Jones, Sylvester; Roy, Brita; Sansone, Christina; Wolf, Judith R L M; Bart, Bradley; Wollersheim, Hub
2017-01-01
Introduction The USA lags behind other high-income countries in many health indicators. Outcome differences are associated with differences in the relative spending between healthcare and social services at the national level. The impact of the ratio and delivery of social and healthcare services on the individual patient’s health is however unknown. ‘Reframing Healthcare Services through the Lens of Co-Production’ (RheLaunCh) will be a cross-Atlantic comparative study of the mechanisms by which healthcare and social service delivery may impact patient health with chronic conditions. Insight into these mechanisms is needed to better and cost-effectively organise healthcare and social services. Methods We designed a mixed methods study to compare the socioeconomic background, needs of and service delivery to patients with congestive heart failure and chronic obstructive pulmonary disease in the USA and the Netherlands. We will conduct: (1) a literature scan to compare national and regional healthcare and social service systems; (2) a retrospective database study to compare patient’s socioeconomic and clinical characteristics and the service use and spending at the national, regional and hospital level; (3) a survey to compare patient perceived quality of life, receipt and experience of service delivery and ability of these services to meet patient needs; and (4) multiple case studies to understand what patients need to better govern their quality of life and how needs are met by services. Ethics and dissemination Ethics approval was granted by the ethics committee of the Radboud University Medical Center (2016–2423) in the Netherlands and by the Human Subjects Research Committee of the Hennepin Health Care System, Inc. (HSR #16–4230) in the USA. Multiple approaches will be used for dissemination of results, including (inter)national research presentations and peer-reviewed publications. A website will be established to support the development of a community of practice. PMID:28882923
Petrescu, Dragos C.; Hollands, Gareth J.; Couturier, Dominique-Laurent; Ng, Yin-Lam; Marteau, Theresa M.
2016-01-01
Background “Nudging”—modifying environments to change people’s behavior, often without their conscious awareness—can improve health, but public acceptability of nudging is largely unknown. Methods We compared acceptability, in the United Kingdom (UK) and the United States of America (USA), of government interventions to reduce consumption of sugar-sweetened beverages. Three nudge interventions were assessed: i. reducing portion Size, ii. changing the Shape of the drink containers, iii. changing their shelf Location; alongside two traditional interventions: iv. Taxation and v. Education. We also tested the hypothesis that describing interventions as working through non-conscious processes decreases their acceptability. Predictors of acceptability, including perceived intervention effectiveness, were also assessed. Participants (n = 1093 UK and n = 1082 USA) received a description of each of the five interventions which varied, by randomisation, in how the interventions were said to affect behaviour: (a) via conscious processes; (b) via non-conscious processes; or (c) no process stated. Acceptability was derived from responses to three items. Results Levels of acceptability for four of the five interventions did not differ significantly between the UK and US samples; reducing portion size was less accepted by the US sample. Within each country, Education was rated as most acceptable and Taxation the least, with the three nudge-type interventions rated between these. There was no evidence to support the study hypothesis: i.e. stating that interventions worked via non-conscious processes did not decrease their acceptability in either the UK or US samples. Perceived effectiveness was the strongest predictor of acceptability for all interventions across the two samples. Conclusion In conclusion, nudge interventions to reduce consumption of sugar-sweetened beverages seem similarly acceptable in the UK and USA, being more acceptable than taxation, but less acceptable than education. Contrary to prediction, we found no evidence that highlighting the non-conscious processes by which nudge interventions may work decreases their acceptability. However, highlighting the effectiveness of all interventions has the potential to increase their acceptability. PMID:27276222
Du Preez, Louis H.; Van Rooyen, Michelle
2015-01-01
Abstract Based on material collected from Pseudemys nelsoni (Reptilia: Chelonia: Emydidae) during a parasite survey of the herpetofauna around Gainesville, Florida, USA, Polystomoides nelsoni sp. n. is described as a new polystome species. This parasite was found in the oral and pharyngeal region of the host. In a sample of nine Pseudemys nelsoni, three specimens were found to release polystome eggs. One turtle was euthanized and dissected and found to be infected in the oral region with 19 specimens belonging to an as-yet-unknown Polystomoides. This is only the fifth Polystomoides recorded from the Nearctic realm. This species is distinguished from known species by a combination of characteristics including marginal hooklet morphology, body length and haptor dimensions. PMID:26798243
Solitary chemoreceptor cell survival is independent of intact trigeminal innervation.
Gulbransen, Brian; Silver, Wayne; Finger, Thomas E
2008-05-01
Nasal solitary chemoreceptor cells (SCCs) are a population of specialized chemosensory epithelial cells presumed to broaden trigeminal chemoreceptivity in mammals (Finger et al. [2003] Proc Natl Acad Sci USA 100:8981-8986). SCCs are innervated by peptidergic trigeminal nerve fibers (Finger et al. [2003]) but it is currently unknown if intact innervation is necessary for SCC development or survival. We tested the dependence of SCCs on innervation by eliminating trigeminal nerve fibers during development with neurogenin-1 knockout mice, during early postnatal development with capsaicin desensitization, and during adulthood with trigeminal lesioning. Our results demonstrate that elimination of innervation at any of these times does not result in decreased SCC numbers. In conclusion, neither SCC development nor mature cell maintenance is dependent on intact trigeminal innervation. (c) 2008 Wiley-Liss, Inc.
A cultured greigite-producing magnetotactic bacterium in a novel group of sulfate-reducing bacteria.
Lefèvre, Christopher T; Menguy, Nicolas; Abreu, Fernanda; Lins, Ulysses; Pósfai, Mihály; Prozorov, Tanya; Pignol, David; Frankel, Richard B; Bazylinski, Dennis A
2011-12-23
Magnetotactic bacteria contain magnetosomes--intracellular, membrane-bounded, magnetic nanocrystals of magnetite (Fe(3)O(4)) or greigite (Fe(3)S(4))--that cause the bacteria to swim along geomagnetic field lines. We isolated a greigite-producing magnetotactic bacterium from a brackish spring in Death Valley National Park, California, USA, strain BW-1, that is able to biomineralize greigite and magnetite depending on culture conditions. A phylogenetic comparison of BW-1 and similar uncultured greigite- and/or magnetite-producing magnetotactic bacteria from freshwater to hypersaline habitats shows that these organisms represent a previously unknown group of sulfate-reducing bacteria in the Deltaproteobacteria. Genomic analysis of BW-1 reveals the presence of two different magnetosome gene clusters, suggesting that one may be responsible for greigite biomineralization and the other for magnetite.
Current knowledge of scoliosis in physiotherapy students trained in the United Kingdom.
Black, D A Jason; Pilcher, Christine; Drake, Shawn; Maude, Erika; Glynn, David
2017-01-01
It has been highlighted in both Poland and the United States of America (USA) that knowledge of idiopathic scoliosis (IS) among physiotherapy students is limited with respect to the 2011 International Society on Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT) guidelines. Early detection of scoliosis and correct initial management is essential in effective care, and thus physiotherapists should be aware of the basic criteria for diagnosis and indications for treatment. The aim of this study was to evaluate the basic knowledge of IS in physiotherapy students trained in the United Kingdom (UK). A previously designed and tested 10-question survey, including knowledge of the 2011 SOSORT guidelines, was transcribed onto an online-survey platform. Questions were designed to analyse knowledge of definition, cause, development, prevalence, diagnosis, treatment and bracing of scoliosis. All UK universities offering physiotherapy degrees were invited to participate, with the programme lead of each institution asked to distribute the questionnaire to all penultimate and final year physiotherapy students (bachelor's and master's degrees). The final number of students who received the study invitation is unknown. The survey link closed after 8 weeks of data collection. Two hundred and six students, split over 12 institutions, successfully completed the questionnaire. Analysis showed that 79% of students recognised when IS is likely to develop, yet only 52% recognised that IS's aetiology is unknown. Eighty-eight percent of students incorrectly defined IS as a 2-dimensional deformity, with only 24% successfully recognising the prevalence of IS within the scoliosis population. Just 12% knew the criteria for diagnosis; however, 93% were unable to recognise the appropriate treatment approach through therapeutic exercise. Finally, 54% of students managed to identify correctly when bracing is recommended for IS. In comparison to previous studies within the USA, students in the UK performed worse in relation to all questions except treatment (7% answered correctly vs 3% in the American study). With only 7% of students able to answer > 50% of the survey questions correctly, there is a clear lack of knowledge of appropriate IS diagnosis and care which could directly impact the information these patients are given within the first contact primary care in the UK.
Population diversity in Pacific herring of the Puget Sound, USA.
Siple, Margaret C; Francis, Tessa B
2016-01-01
Demographic, functional, or habitat diversity can confer stability on populations via portfolio effects (PEs) that integrate across multiple ecological responses and buffer against environmental impacts. The prevalence of these PEs in aquatic organisms is as yet unknown, and can be difficult to quantify; however, understanding mechanisms that stabilize populations in the face of environmental change is a key concern in ecology. Here, we examine PEs in Pacific herring (Clupea pallasii) in Puget Sound (USA) using a 40-year time series of biomass data for 19 distinct spawning population units collected using two survey types. Multivariate auto-regressive state-space models show independent dynamics among spawning subpopulations, suggesting that variation in herring production is partially driven by local effects at spawning grounds or during the earliest life history stages. This independence at the subpopulation level confers a stabilizing effect on the overall Puget Sound spawning stock, with herring being as much as three times more stable in the face of environmental perturbation than a single population unit of the same size. Herring populations within Puget Sound are highly asynchronous but share a common negative growth rate and may be influenced by the Pacific Decadal Oscillation. The biocomplexity in the herring stock shown here demonstrates that preserving spatial and demographic diversity can increase the stability of this herring population and its availability as a resource for consumers.
King, Gary M.; Judd, Craig; Kuske, Cheryl R.; Smith, Conor
2012-01-01
We used high throughput pyrosequencing to characterize stomach and gut content microbiomes of Crassostrea virginica, the Easter oyster, obtained from two sites, one in Barataria Bay (Hackberry Bay) and the other in Terrebonne Bay (Lake Caillou), Louisiana, USA. Stomach microbiomes in oysters from Hackberry Bay were overwhelmingly dominated by Mollicutes most closely related to Mycoplasma; a more rich community dominated by Planctomyctes occurred in Lake Caillou oyster stomachs. Gut communities for oysters from both sites differed from stomach communities, and harbored a relatively diverse assemblage of phylotypes. Phylotypes most closely related to Shewanella and a Chloroflexi strain dominated the Lake Caillou and Hackberry Bay gut microbiota, respectively. While many members of the stomach and gut microbiomes appeared to be transients or opportunists, a putative core microbiome was identified based on phylotypes that occurred in all stomach or gut samples only. The putative core stomach microbiome comprised 5 OTUs in 3 phyla, while the putative core gut microbiome contained 44 OTUs in 12 phyla. These results collectively revealed novel microbial communities within the oyster digestive system, the functions of the oyster microbiome are largely unknown. A comparison of microbiomes from Louisiana oysters with bacterial communities reported for other marine invertebrates and fish indicated that molluscan microbiomes were more similar to each other than to microbiomes of polychaetes, decapods and fish. PMID:23251548
King, Gary M.; Judd, Craig; Kuske, Cheryl R.; ...
2012-12-12
In this paper, we used high throughput pyrosequencing to characterize stomach and gut content microbiomes of Crassostrea virginica, the Easter oyster, obtained from two sites, one in Barataria Bay (Hackberry Bay) and the other in Terrebonne Bay (Lake Caillou), Louisiana, USA. Stomach microbiomes in oysters from Hackberry Bay were overwhelmingly dominated by Mollicutes most closely related to Mycoplasma; a more rich community dominated by Planctomyctes occurred in Lake Caillou oyster stomachs. Gut communities for oysters from both sites differed from stomach communities, and harbored a relatively diverse assemblage of phylotypes. Phylotypes most closely related to Shewanella and a Chloroflexi strainmore » dominated the Lake Caillou and Hackberry Bay gut microbiota, respectively. While many members of the stomach and gut microbiomes appeared to be transients or opportunists, a putative core microbiome was identified based on phylotypes that occurred in all stomach or gut samples only. The putative core stomach microbiome comprised 5 OTUs in 3 phyla, while the putative core gut microbiome contained 44 OTUs in 12 phyla. These results collectively revealed novel microbial communities within the oyster digestive system, the functions of the oyster microbiome are largely unknown. Finally, a comparison of microbiomes from Louisiana oysters with bacterial communities reported for other marine invertebrates and fish indicated that molluscan microbiomes were more similar to each other than to microbiomes of polychaetes, decapods and fish.« less
The history of neurocritical care.
Wijdicks, E F M
2017-01-01
Critical care medicine came into sharp focus in the second part of the 20th century. The care of acutely ill neurologic patients in the USA may have originated in postoperative neurosurgical units, but for many years patients with neurocritical illness were admitted to intensive care units next to patients with general medical or surgical conditions. Neurologists may have had their first exposure to the complexity of neurocritical care during the poliomyelitis epidemics, but few were interested. Much later, the development of neurocritical care as a legitimate subspecialty was possible as a result of a new cadre of neurologists, with support by departments of neurosurgery and anesthesia, who appreciated their added knowledge and expertise in care of acute neurologic illness. Fellowship programs have matured in the US and training programs in certain European countries. Certification in the USA is possible through the American Academy of Neurology United Council of Neurologic Specialties. Most neurointensivists had a formal neurology training. This chapter is a brief analysis of the development of the specialty critical care neurology and how it gained strength, what it is to be a neurointensivist, what the future of care of these patients may hold, and what it takes for neurointensivists to stay exemplary. This chapter revisits some of the earlier known and previously unknown landmarks in the history of neurocritical care. © 2017 Elsevier B.V. All rights reserved.
Association between sepsis and Rocky Mountain spotted fever.
Bacci, Marcelo Rodrigues; Namura, José Jorge
2012-12-06
Rocky Mountain spotted fever (RMSF) is a disease caused by the Gram-negative coccobacillus Rickettsia ricketsii which has been on the rise since the last decade in the USA. The symptoms are common to the many viral diseases, and the classic triad of fever, rash and headache is not always present when RMSF is diagnosed. It may progress to severe cases such as renal failure, disseminated intravascular coagulation and septicaemia. This report aims to present a fulminant case of RMSF associated with sepsis. It describes a female patient's case that quickly progressed to sepsis and death. The patient showed non-specific symptoms for 5 days before being admitted to a hospital. The fact that she lived in an area highly infested with Amblyomma aureolatum ticks was unknown to the medical staff until the moment she died.
Association between sepsis and Rocky Mountain spotted fever
Bacci, Marcelo Rodrigues; Namura, José Jorge
2012-01-01
Rocky Mountain spotted fever (RMSF) is a disease caused by the Gram-negative coccobacillus Rickettsia ricketsii which has been on the rise since the last decade in the USA. The symptoms are common to the many viral diseases, and the classic triad of fever, rash and headache is not always present when RMSF is diagnosed. It may progress to severe cases such as renal failure, disseminated intravascular coagulation and septicaemia. This report aims to present a fulminant case of RMSF associated with sepsis. It describes a female patient's case that quickly progressed to sepsis and death. The patient showed non-specific symptoms for 5 days before being admitted to a hospital. The fact that she lived in an area highly infested with Amblyomma aureolatum ticks was unknown to the medical staff until the moment she died. PMID:23220832
Biocontainment laboratory risk assessment: perspectives and considerations.
Patterson, Amy; Fennington, Kelly; Bayha, Ryan; Wax, Diane; Hirschberg, Rona; Boyd, Nancy; Kurilla, Michael
2014-07-01
The ability to respond to public health emergencies involving infectious diseases as well as our ability to adequately prepare for as yet unknown or unrecognized emerging infectious diseases requires suitable facilities within which scientific investigations can take place. To ensure the safe conduct of such investigations so that laboratory workers and the general public are protected from potential consequences of accidental or intentional release of high consequence pathogens, special containment facilities have been designed and constructed. Evaluation of the adequacy of containment for these types of investigations requires a risk assessment (RA) as part of the overall construction project for these types of laboratories. A discussion of the RA process along with considerations that impact the design of such studies and the overall results is presented. Published 2014. This article is a US Government work and is in the public domain in the USA.
Synthetic Pot: Not Your Grandfather’s Marijuana
Ford, Benjamin M.; Tai, Sherrica; Fantegrossi, William E.
2017-01-01
In the early 2000’s in Europe and shortly thereafter in the USA, it was reported that “legal” forms of marijuana were being sold under the name K2 and/or Spice. Active ingredients in K2/Spice products were determined to be synthetic cannabinoids (SCBs), producing psychotropic actions via CB1 cannabinoid receptors, similar to those of Δ9-THC, the primary active constituent in marijuana. Often abused by adolescents and military personnel to elude detection in drug tests due to their lack of structural similarity to Δ9-THC, SCBs are falsely marketed as safe marijuana substitutes. Instead, SCBs are a highly structural diverse group of compounds, easily synthesized, which produce very dangerous adverse effects occurring by, as of yet, unknown mechanisms. Therefore, available evidence indicates that K2/Spice products are clearly not safe marijuana alternatives. PMID:28162792
From orientation to magnitudes in paleostress determinations using fault slip data
NASA Astrophysics Data System (ADS)
Angelier, Jacques
Determinations of reduced stress tensors using fault slip data yield the orientation of principal stress axes and the ratio Φ of the differences between principal stress magnitudes. The use of rupture and friction laws allows determination of the two remaining unknowns, that is, the reconstruction of the complete stress tensor. Taking into account the depth of overburden brings an additional constraint. The method is applied and discussed in the case of the Hoover Dam site (western U.S.A.), where large data sets and rock mechanics information are available. Differences between intact sample and rock mass properties account for apparent disagreements between paleostress levels determined in similar tectonic environments. Pore pressure plays an important role; where information about pore pressure is absent, zero and hydrostatic pore pressure cases should be considered as limits.
Gutnik, Lily; Dieleman, Joseph; Dare, Anna J; Ramos, Margarita S; Riviello, Robert; Meara, John G; Yamey, Gavin; Shrime, Mark G
2015-11-09
The funds available for global surgical delivery, capacity building and research are unknown and presumed to be low. Meanwhile, conditions amenable to surgery are estimated to account for nearly 30% of the global burden of disease. We describe funds given to these efforts from the USA, the world's largest donor nation. Retrospective database review. US Agency for International Development (USAID), National Institute of Health (NIH), Foundation Center and registered US charitable organisations were searched for financial data on any organisation giving exclusively to surgical care in low and middle income countries (LMICs). For USAID, NIH and Foundation Center all available data for all years were included. The five recent years of financial data per charitable organisation were included. All nominal dollars were adjusted for inflation by converting to 2014 US dollars. USA. USAID, NIH, Foundation Center, Charitable Organisations. Cumulative funds appropriated to global surgery. 22 NIH funded projects (totalling $31.3 million) were identified, primarily related to injury and trauma. Six relevant USAID projects were identified-all obstetric fistula care totalling $438 million. A total of $105 million was given to universities and charitable organisations by US foundations for 12 different surgical specialties. 95 US charitable organisations representing 14 specialties totalled revenue of $2.67 billion and expenditure of $2.5 billion. Current funding flows to surgical care in LMICs are poorly understood. US funding predominantly comes from private charitable organisations, is often narrowly focused and does not always reflect local needs or support capacity building. Improving surgical care, and embedding it within national health systems in LMICs, will likely require greater financial investment. Tracking funds targeting surgery helps to quantify and clarify current investments and funding gaps, ensures resources materialise from promises and promotes transparency within global health financing. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
Dieleman, Joseph; Dare, Anna J; Ramos, Margarita S; Riviello, Robert; Meara, John G; Yamey, Gavin; Shrime, Mark G
2015-01-01
Objective The funds available for global surgical delivery, capacity building and research are unknown and presumed to be low. Meanwhile, conditions amenable to surgery are estimated to account for nearly 30% of the global burden of disease. We describe funds given to these efforts from the USA, the world's largest donor nation. Design Retrospective database review. US Agency for International Development (USAID), National Institute of Health (NIH), Foundation Center and registered US charitable organisations were searched for financial data on any organisation giving exclusively to surgical care in low and middle income countries (LMICs). For USAID, NIH and Foundation Center all available data for all years were included. The five recent years of financial data per charitable organisation were included. All nominal dollars were adjusted for inflation by converting to 2014 US dollars. Setting USA. Participants USAID, NIH, Foundation Center, Charitable Organisations. Primary and secondary outcome measures Cumulative funds appropriated to global surgery. Results 22 NIH funded projects (totalling $31.3 million) were identified, primarily related to injury and trauma. Six relevant USAID projects were identified—all obstetric fistula care totalling $438 million. A total of $105 million was given to universities and charitable organisations by US foundations for 12 different surgical specialties. 95 US charitable organisations representing 14 specialties totalled revenue of $2.67 billion and expenditure of $2.5 billion. Conclusions and relevance Current funding flows to surgical care in LMICs are poorly understood. US funding predominantly comes from private charitable organisations, is often narrowly focused and does not always reflect local needs or support capacity building. Improving surgical care, and embedding it within national health systems in LMICs, will likely require greater financial investment. Tracking funds targeting surgery helps to quantify and clarify current investments and funding gaps, ensures resources materialise from promises and promotes transparency within global health financing. PMID:26553831
The history and current status of glyphosate.
Duke, Stephen O
2018-05-01
Glyphosate is the only herbicide to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS). It is a high use rate, non-selective herbicide that translocates primarily to metabolic sinks, killing meristematic tissues away from the application site. Its phloem-mobile properties and slow action in killing weeds allow the herbicide to move throughout the plant to kill all meristems, making it effective for perennial weed control. Since commercialization in 1974, its use has grown to dominate the herbicide market. Much of its use is on transgenic, glyphosate-resistant crops (GRCs), which have been the dominant transgenic crops worldwide. GRCs with glyphosate provided the most effective and inexpensive weed management technology in history for a decade or more. However, as a consequence of the rapid increase in glyphosate-resistant (GR) weeds, the effectiveness of glyphosate use in GRCs is declining. Critics have claimed that glyphosate-treated GRCs have altered mineral nutrition and increased susceptibility to plant pathogens because of glyphosate's ability to chelate divalent metal cations, but the complete resistance of GRCs to glyphosate indicates that chelating metal cations do not contribute to the herbicidal activity or significantly affect mineral nutrition. The rates of increases in yields of maize, soybean, and cotton in the USA have been unchanged after high adoption rates of GRCs. Glyphosate is toxic to some plant pathogens, and thereby can act as a fungicide in GRCs. Ultra-low doses of glyphosate stimulate plant growth in glyphosate-susceptible plants by unknown mechanisms. Despite rapid and widespread increases in GR weeds, glyphosate use has not decreased. However, as GR weeds increase, adoption of alternative technologies will eventually lead to decreased use. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.
NASA Astrophysics Data System (ADS)
Gawałkiewicz, Rafał
2015-12-01
There are many surveying methods to measure the inclination of a chimney with the use of classical protractor instruments (Theo 010A/B, T2 Wild), electronic theodolites (TC2002 Wild-Leica), electronic total stations, including mirrorless ones, allowing to define indirectly the course of the construction's axis on the selected observation levels. The methods are the following: indentations, direct projection, double-edged method, polar method with the option of mirrorless measurement. At the moment a very practical and quick measurement technology, significantly eliminating the influence of human errors on the observation results, is laser scanning. The article presents the results of the scanning of 120-metres high reinforced concrete industrial chimney of the Cement Plant "Ożarów", with the application of modern scanning total station VX Spatial Station by Trimble, as an alternative to the methods applied so far. The advantage of scanning is the possibility to obtain a point cloud, which, apart from the information on the course of the chimney axis in the space, provides detail information on the real shape and deformations of the coating of the object's core.
Meteorology and GNSS? What is the benefit?
NASA Astrophysics Data System (ADS)
Drummond, P.; Grünig, S.
2010-12-01
Due to the strong correlation between water vapor in the atmosphere and GNSS tropospheric propagation delays, we can estimate the Integrated Precipitable Water Vapor (IPWV) in the atmosphere through GNSS measurements. This parameter is crucial for meteorologists as the water content in the atmosphere is a key parameter in the weather models. The Total Electron Content (TEC) in the ionosphere has a huge impact on the ionospheric propagation delay in GNSS signals. By computing the ionospheric delay from GNSS measurements it is possible to predict the TEC which is an excellent indicator for ionospheric activity. The benefit is that we can estimate the influence on the RTK performance from TEC values. The atmospheric feature in the Trimble Atmosphere App (as well as in VRSNet software) allows computing both IPWV and TEC values from a CORS network. IPWV is computed using surface meteorological data such as temperature and pressure as well as radiosonde data. The results are shown in a table like form as well as in numerous graphical forms such as contour and surface plots, station and condition charts. The computed values can be animated in a movie over the last 24 hours.
Using Parameters of Dynamic Pulse Function for 3d Modeling in LOD3 Based on Random Textures
NASA Astrophysics Data System (ADS)
Alizadehashrafi, B.
2015-12-01
The pulse function (PF) is a technique based on procedural preprocessing system to generate a computerized virtual photo of the façade with in a fixed size square(Alizadehashrafi et al., 2009, Musliman et al., 2010). Dynamic Pulse Function (DPF) is an enhanced version of PF which can create the final photo, proportional to real geometry. This can avoid distortion while projecting the computerized photo on the generated 3D model(Alizadehashrafi and Rahman, 2013). The challenging issue that might be handled for having 3D model in LoD3 rather than LOD2, is the final aim that have been achieved in this paper. In the technique based DPF the geometries of the windows and doors are saved in an XML file schema which does not have any connections with the 3D model in LoD2 and CityGML format. In this research the parameters of Dynamic Pulse Functions are utilized via Ruby programming language in SketchUp Trimble to generate (exact position and deepness) the windows and doors automatically in LoD3 based on the same concept of DPF. The advantage of this technique is automatic generation of huge number of similar geometries e.g. windows by utilizing parameters of DPF along with defining entities and window layers. In case of converting the SKP file to CityGML via FME software or CityGML plugins the 3D model contains the semantic database about the entities and window layers which can connect the CityGML to MySQL(Alizadehashrafi and Baig, 2014). The concept behind DPF, is to use logical operations to project the texture on the background image which is dynamically proportional to real geometry. The process of projection is based on two vertical and horizontal dynamic pulses starting from upper-left corner of the background wall in down and right directions respectively based on image coordinate system. The logical one/zero on the intersections of two vertical and horizontal dynamic pulses projects/does not project the texture on the background image. It is possible to define priority for each layer. For instance the priority of the door layer can be higher than window layer which means that window texture cannot be projected on the door layer. Orthogonal and rectified perpendicular symmetric photos of the 3D objects that are proportional to the real façade geometry must be utilized for the generation of the output frame for DPF. The DPF produces very high quality and small data size of output image files in quite smaller dimension compare with the photorealistic texturing method. The disadvantage of DPF is its preprocessing method to generate output image file rather than online processing to generate the texture within the 3D environment such as CityGML. Furthermore the result of DPF can be utilized for 3D model in LOD2 rather than LOD3. In the current work the random textures of the window layers are created based on parameters of DPF within Ruby console of SketchUp Trimble to generate the deeper geometries of the windows and their exact position on the façade automatically along with random textures to increase Level of Realism (LoR)(Scarpino, 2010). As the output frame in DPF is proportional to real geometry (height and width of the façade) it is possible to query the XML database and convert them to units such as meter automatically. In this technique, the perpendicular terrestrial photo from the façade is rectified by employing projective transformation based on the frame which is in constrain proportion to real geometry. The rectified photos which are not suitable for texturing but necessary for measuring, can be resized in constrain proportion to real geometry before measuring process. Height and width of windows, doors, horizontal and vertical distance between windows from upper left corner of the photo dimensions of doors and windows are parameters that should be measured to run the program as a plugins in SketchUp Trimble. The system can use these parameters and texture file names and file paths to create the façade semi-automatically. To avoid leaning geometry the textures of windows, doors and etc, should be cropped and rectified from perpendicular photos, so that they can be used in the program to create the whole façade along with its geometries. Texture enhancement should be done in advance such as removing disturbing objects, exposure setting, left-right up-down transformation, and so on. In fact, the quality, small data size, scale and semantic database for each façade are the prominent advantages of this method.
NASA Astrophysics Data System (ADS)
Korzeniowska, Karolina; Mandlburger, Gottfried; Klimczyk, Agata
2013-04-01
The paper presents an evaluation of different terrain point extraction algorithms for Airborne Laser Scanning (ALS) point clouds. The research area covers eight test sites in the Małopolska Province (Poland) with varying point density between 3-15points/m² and surface as well as land cover characteristics. In this paper the existing implementations of algorithms were considered. Approaches based on mathematical morphology, progressive densification, robust surface interpolation and segmentation were compared. From the group of morphological filters, the Progressive Morphological Filter (PMF) proposed by Zhang K. et al. (2003) in LIS software was evaluated. From the progressive densification filter methods developed by Axelsson P. (2000) the Martin Isenburg's implementation in LAStools software (LAStools, 2012) was chosen. The third group of methods are surface-based filters. In this study, we used the hierarchic robust interpolation approach by Kraus K., Pfeifer N. (1998) as implemented in SCOP++ (Trimble, 2012). The fourth group of methods works on segmentation. From this filtering concept the segmentation algorithm available in LIS was tested (Wichmann V., 2012). The main aim in executing the automatic classification for ground extraction was operating in default mode or with default parameters which were selected by the developers of the algorithms. It was assumed that the default settings were equivalent to the parameters on which the best results can be achieved. In case it was not possible to apply an algorithm in default mode, a combination of the available and most crucial parameters for ground extraction were selected. As a result of these analyses, several output LAS files with different ground classification were achieved. The results were described on the basis of qualitative and quantitative analyses, both being in a formal description. The classification differences were verified on point cloud data. Qualitative verification of ground extraction was made on the basis of a visual inspection of the results (Sithole G., Vosselman G., 2004; Meng X. et al., 2010). The results of these analyses were described as a graph using weighted assumption. The quantitative analyses were evaluated on a basis of Type I, Type II and Total errors (Sithole G., Vosselman G., 2003). The achieved results show that the analysed algorithms yield different classification accuracies depending on the landscape and land cover. The simplest terrain for ground extraction was flat rural area with sparse vegetation. The most difficult were mountainous areas with very dense vegetation where only a few ground points were available. Generally the LAStools algorithm gives good results in every type of terrain, but the ground surface is too smooth. The LIS Progressive Morphological Filter algorithm gives good results in forested flat and low slope areas. The surface-based algorithm from SCOP++ gives good results in mountainous areas - both forested and built-up because it better preserves steep slopes, sharp ridges and breaklines, but sometimes it fails to remove off-terrain objects from the ground class. The segmentation-based algorithm in LIS gives quite good results in built-up flat areas, but in forested areas it does not work well. Bibliography: Axelsson, P., 2000. DEM generation from laser scanner data using adaptive TIN models. International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XXXIII (Pt. B4/1), 110- 117 Kraus, K., Pfeifer, N., 1998. Determination of terrain models in wooded areas with airborne laser scanner data. ISPRS Journal of Photogrammetry & Remote Sensing 53 (4), 193-203 LAStools website http://www.cs.unc.edu/~isenburg/lastools/ (verified in September 2012) Meng, X., Currit, N., Zhao, K., 2010. Ground Filtering Algorithms for Airborne LiDAR Data: A Review of Critical Issues. Remote Sensing 2, 833-860 Sithole, G., Vosselman, G., 2003. Report: ISPRS Comparison of Filters. Commission III, Working Group 3. Department of Geodesy, Faculty of Civil Engineering and Geosciences, Delft University of technology, The Netherlands Sithole, G., Vosselman, G., 2004. Experimental comparison of filter algorithms for bare-Earth extraction form airborne laser scanning point clouds. ISPRS Journal of Photogrammetry & Remote Sensing 59, 85-101 Trimble, 2012 http://www.trimble.com/geospatial/aerial-software.aspx (verified in November 2012) Wichmann, V., 2012. LIS Command Reference, LASERDATA GmbH, 1-231 Zhang, K., Chen, S.-C., Whitman, D., Shyu, M.-L., Yan, J., Zhang, C., 2003. A progressive morphological filter for removing non-ground measurements from airborne LIDAR data. IEEE Transactions on Geoscience and Remote Sensing, 41(4), 872-882
Park, Eun Sug; Hopke, Philip K; Oh, Man-Suk; Symanski, Elaine; Han, Daikwon; Spiegelman, Clifford H
2014-07-01
There has been increasing interest in assessing health effects associated with multiple air pollutants emitted by specific sources. A major difficulty with achieving this goal is that the pollution source profiles are unknown and source-specific exposures cannot be measured directly; rather, they need to be estimated by decomposing ambient measurements of multiple air pollutants. This estimation process, called multivariate receptor modeling, is challenging because of the unknown number of sources and unknown identifiability conditions (model uncertainty). The uncertainty in source-specific exposures (source contributions) as well as uncertainty in the number of major pollution sources and identifiability conditions have been largely ignored in previous studies. A multipollutant approach that can deal with model uncertainty in multivariate receptor models while simultaneously accounting for parameter uncertainty in estimated source-specific exposures in assessment of source-specific health effects is presented in this paper. The methods are applied to daily ambient air measurements of the chemical composition of fine particulate matter ([Formula: see text]), weather data, and counts of cardiovascular deaths from 1995 to 1997 for Phoenix, AZ, USA. Our approach for evaluating source-specific health effects yields not only estimates of source contributions along with their uncertainties and associated health effects estimates but also estimates of model uncertainty (posterior model probabilities) that have been ignored in previous studies. The results from our methods agreed in general with those from the previously conducted workshop/studies on the source apportionment of PM health effects in terms of number of major contributing sources, estimated source profiles, and contributions. However, some of the adverse source-specific health effects identified in the previous studies were not statistically significant in our analysis, which probably resulted because we incorporated parameter uncertainty in estimated source contributions that has been ignored in the previous studies into the estimation of health effects parameters. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Impact of survey workflow on precision and accuracy of terrestrial LiDAR datasets
NASA Astrophysics Data System (ADS)
Gold, P. O.; Cowgill, E.; Kreylos, O.
2009-12-01
Ground-based LiDAR (Light Detection and Ranging) survey techniques are enabling remote visualization and quantitative analysis of geologic features at unprecedented levels of detail. For example, digital terrain models computed from LiDAR data have been used to measure displaced landforms along active faults and to quantify fault-surface roughness. But how accurately do terrestrial LiDAR data represent the true ground surface, and in particular, how internally consistent and precise are the mosaiced LiDAR datasets from which surface models are constructed? Addressing this question is essential for designing survey workflows that capture the necessary level of accuracy for a given project while minimizing survey time and equipment, which is essential for effective surveying of remote sites. To address this problem, we seek to define a metric that quantifies how scan registration error changes as a function of survey workflow. Specifically, we are using a Trimble GX3D laser scanner to conduct a series of experimental surveys to quantify how common variables in field workflows impact the precision of scan registration. Primary variables we are testing include 1) use of an independently measured network of control points to locate scanner and target positions, 2) the number of known-point locations used to place the scanner and point clouds in 3-D space, 3) the type of target used to measure distances between the scanner and the known points, and 4) setting up the scanner over a known point as opposed to resectioning of known points. Precision of the registered point cloud is quantified using Trimble Realworks software by automatic calculation of registration errors (errors between locations of the same known points in different scans). Accuracy of the registered cloud (i.e., its ground-truth) will be measured in subsequent experiments. To obtain an independent measure of scan-registration errors and to better visualize the effects of these errors on a registered point cloud, we scan from multiple locations an object of known geometry (a cylinder mounted above a square box). Preliminary results show that even in a controlled experimental scan of an object of known dimensions, there is significant variability in the precision of the registered point cloud. For example, when 3 scans of the central object are registered using 4 known points (maximum time, maximum equipment), the point clouds align to within ~1 cm (normal to the object surface). However, when the same point clouds are registered with only 1 known point (minimum time, minimum equipment), misalignment of the point clouds can range from 2.5 to 5 cm, depending on target type. The greater misalignment of the 3 point clouds when registered with fewer known points stems from the field method employed in acquiring the dataset and demonstrates the impact of field workflow on LiDAR dataset precision. By quantifying the degree of scan mismatch in results such as this, we can provide users with the information needed to maximize efficiency in remote field surveys.
Zipper, Carl E; Donovan, Patricia F; Jones, Jess W; Li, Jing; Price, Jennifer E; Stewart, Roger E
2016-01-15
The Powell River of southwestern Virginia and northeastern Tennessee, USA, drains a watershed with extensive coal surface mining, and it hosts exceptional biological richness, including at-risk species of freshwater mussels, downstream of mining-disturbed watershed areas. We investigated spatial and temporal patterns of watershed mining disturbance; their relationship to water quality change in the section of the river that connects mining areas to mussel habitat; and relationships of mining-related water constituents to measures of recent and past mussel status. Freshwater mussels in the Powell River have experienced significant declines over the past 3.5 decades. Over that same period, surface coal mining has influenced the watershed. Water-monitoring data collected by state and federal agencies demonstrate that dissolved solids and associated constituents that are commonly influenced by Appalachian mining (specific conductance, pH, hardness and sulfates) have experienced increasing temporal trends from the 1960s through ~2008; but, of those constituents, only dissolved solids concentrations are available widely within the Powell River since ~2008. Dissolved solids concentrations have stabilized in recent years. Dissolved solids, specific conductance, pH, and sulfates also exhibited spatial patterns that are consistent with dilution of mining influence with increasing distance from mined areas. Freshwater mussel status indicators are correlated negatively with dissolved solids concentrations, spatially and temporally, but the direct causal mechanisms responsible for mussel declines remain unknown. Copyright © 2015 Elsevier B.V. All rights reserved.
Lorch, Jeffrey M.; Minnis, Andrew M.; Meteyer, Carol U.; Redell, Jennifer A.; White, J. Paul; Kaarakka, Heather M.; Muller, Laura K.; Lindner, David L.; Verant, Michelle L.; Shearn-Bochsler, Valerie I.; Blehert, David S.
2014-01-01
Before the discovery of white-nose syndrome (WNS), a fungal disease caused by Pseudogymnoascus destructans, there were no reports of fungal skin infections in bats during hibernation. In 2011, bats with grossly visible fungal skin infections similar in appearance to WNS were reported from multiple sites in Wisconsin, USA, a state outside the known range of P. destructans and WNS at that time. Tape impressions or swab samples were collected from affected areas of skin from bats with these fungal infections in 2012 and analyzed by microscopy, culture, or direct DNA amplification and sequencing of the fungal internal transcribed spacer region (ITS). A psychrophilic species ofTrichophyton was isolated in culture, detected by direct DNA amplification and sequencing, and observed on tape impressions. Deoxyribonucleic acid indicative of the same fungus was also detected on three of five bat carcasses collected in 2011 and 2012 from Wisconsin, Indiana, and Texas, USA. Superficial fungal skin infections caused by Trichophyton sp. were observed in histopathology for all three bats. Sequencing of the ITS of Trichophyton sp., along with its inability to grow at 25 C, indicated that it represented a previously unknown species, described herein as Trichophyton redellii sp. nov. Genetic diversity present within T. redellii suggests it is native to North America but that it had been overlooked before enhanced efforts to study fungi associated with bats in response to the emergence of WNS.
Lloyd, Sonja J; LaPatra, Scott E; Snekvik, Kevin R; St-Hilaire, Sophie; Cain, Kenneth D; Call, Douglas R
2008-11-20
Strawberry disease (SD) in the USA is a skin disorder of unknown etiology that occurs in rainbow trout Oncorhynchus mykiss and is characterized by bright red inflammatory lesions. To identify a candidate bacterial agent responsible for SD, we constructed 16S rDNA libraries from 7 SD lesion samples and 2 apparently healthy skin samples from SD-affected fish. A 16S rDNA sequence highly similar to members of the order Rickettsiales was present in 3 lesion libraries at 1%, 32% and 54% prevalence, but this sequence was not found in either healthy tissue library. Based on phylogenetic analysis, this Rickettsia-like organism (RLO) sequence is most closely related to 16S rDNA sequences of bacteria that may form a novel lineage within the Rickettsiales. We used nested PCR assays to screen 25 SD-affected fish for RLO or Flavobacterium psychrophilum DNA. Sixteen lesion samples were positive for the RLO sequence and 4 of the matched healthy samples were positive resulting in a significant association between SD lesions and presence of RLO DNA. While F. psychrophilum is reportedly associated with 'cold water strawberry disease' in the UK, we found no significant association between SD lesions and the presence of F. psychrophilum DNA. The statistical association between SD lesions and presence of RLO DNA is not proof of etiology, but these data suggest that RLO may play a role in SD in southern Idaho, USA.
Electronic nicotine delivery systems: adult use and awareness of the 'e-cigarette' in the USA.
Regan, Annette K; Promoff, Gabbi; Dube, Shanta R; Arrazola, Rene
2013-01-01
Electronic nicotine delivery systems (ENDS), also referred to as electronic cigarettes or e-cigarettes, were introduced into the US market in 2007. Despite concerns regarding the long-term health impact of this product, there is little known about awareness and use of ENDS among adults in the USA. A consumer-based mail-in survey (ConsumerStyles) was completed by 10,587 adults (≥ 18 years) in 2009 and 10,328 adults in 2010. Data from these surveys were used to monitor awareness, ever use and past month use of ENDS from 2009 to 2010 and to assess demographic characteristics and tobacco use of ENDS users. In this US sample, awareness of ENDS doubled from 16.4% in 2009 to 32.2% in 2010 and ever use more than quadrupled from 2009 (0.6%) to 2010 (2.7%). Ever use of ENDS was most common among women and those with lower education, although these were not the groups who had heard of ENDS most often. Current smokers and tobacco users were most likely to try ENDS. However, current smokers who had tried ENDS did not say they planned to quit smoking more often than smokers who had never tried them. Given the large increase in awareness and ever use of ENDS during this 1-year period and the unknown impact of ENDS use on cigarette smoking behaviours and long-term health, continued monitoring of these products is needed.
Geogenic organic contaminants in the low-rank coal-bearing Carrizo-Wilcox aquifer of East Texas, USA
NASA Astrophysics Data System (ADS)
Chakraborty, Jayeeta; Varonka, Matthew; Orem, William; Finkelman, Robert B.; Manton, William
2017-06-01
The organic composition of groundwater along the Carrizo-Wilcox aquifer in East Texas (USA), sampled from rural wells in May and September 2015, was examined as part of a larger study of the potential health and environmental effects of organic compounds derived from low-rank coals. The quality of water from the low-rank coal-bearing Carrizo-Wilcox aquifer is a potential environmental concern and no detailed studies of the organic compounds in this aquifer have been published. Organic compounds identified in the water samples included: aliphatics and their fatty acid derivatives, phenols, biphenyls, N-, O-, and S-containing heterocyclic compounds, polycyclic aromatic hydrocarbons (PAHs), aromatic amines, and phthalates. Many of the identified organic compounds (aliphatics, phenols, heterocyclic compounds, PAHs) are geogenic and originated from groundwater leaching of young and unmetamorphosed low-rank coals. Estimated concentrations of individual compounds ranged from about 3.9 to 0.01 μg/L. In many rural areas in East Texas, coal strata provide aquifers for drinking water wells. Organic compounds observed in groundwater are likely to be present in drinking water supplied from wells that penetrate the coal. Some of the organic compounds identified in the water samples are potentially toxic to humans, but at the estimated levels in these samples, the compounds are unlikely to cause acute health problems. The human health effects of low-level chronic exposure to coal-derived organic compounds in drinking water in East Texas are currently unknown, and continuing studies will evaluate possible toxicity.
Genomic Insights into Geothermal Spring Community Members using a 16S Agnostic Single-Cell Approach
NASA Astrophysics Data System (ADS)
Bowers, R. M.
2016-12-01
INSTUTIONS (ALL): DOE Joint Genome Institute, Walnut Creek, CA USA. Bigelow Laboratory for Ocean Sciences, East Boothbay, ME USA. Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada. ABSTRACT BODY: With recent advances in DNA sequencing, rapid and affordable screening of single-cell genomes has become a reality. Single-cell sequencing is a multi-step process that takes advantage of any number of single-cell sorting techniques, whole genome amplification (WGA), and 16S rRNA gene based PCR screening to identify the microbes of interest prior to shotgun sequencing. However, the 16S PCR based screening step is costly and may lead to unanticipated losses of microbial diversity, as cells that do not produce a clean 16S amplicon are typically omitted from downstream shotgun sequencing. While many of the sorted cells that fail the 16S PCR step likely originate from poor quality amplified DNA, some of the cells with good WGA kinetics may instead represent bacteria or archaea with 16S genes that fail to amplify due to primer mis-matches or the presence of intervening sequences. Using cell material from Dewar Creek, a hot spring in British Columbia, we sequenced all sorted cells with good WGA kinetics irrespective of their 16S amplification success. We show that this high-throughput approach to single-cell sequencing (i) can reduce the overall cost of single-cell genome production, and (ii). may lead to the discovery of previously unknown branches on the microbial tree of life.
NASA Astrophysics Data System (ADS)
Morrill, P. L.; Rietze, A.; Kohl, L.; Miles, S.; Kavanagh, H.; Cox, A.; Brazelton, W. J.; Ishii, S.; Sherwood Lollar, B.; Schrenk, M. O.; Nealson, K. H.; Ziegler, S. E.; Ono, S.; Wang, D. T.; Lang, S. Q.; Cumming, E.
2014-12-01
Ultra-basic reducing springs at continental sites of serpentinization act as portals into the biogeochemistry of a subsurface ultramafic environment rich in hydrogen and methane gases. Field data and results from substrate addition microcosm experiments will be presented from two contrasting continental sites of serpentinization: the Tablelands, NL, CAN and The Cedars, CA, USA both Phanerozoic in age. These continental sites share geochemical characteristics that make these environments challenging for life, such as high pH, low Eh, scarce electron acceptors, and limited dissolved inorganic carbon for autotrophic growth. However, microbiological analyses have demonstrated that life does indeed exist in these environments. While environmental genomic studies indicated the potential metabolic capabilities of microorganisms in the sites, actual microbial metabolic activities in these environments remain unknown. To expand the understanding of biogeochemistry of the sites, we are conducting studies focusing on chemical and isotopic measurements, carbon substrate utilization, energy sources, and metabolic pathways of the microorganisms. Thus far, in situ geochemical data suggests that the methane from the Tablelands is primarily non-microbial, while the methane from The Cedars likely has some microbial contributions. To date, substrate addition microcosm experiments show no microbial production of methane from Tablelands' water and sediments. However, microbial carbon monoxide utilization has been observed in Tableland microcosms, but not in The Cedars microcosms. These results demonstrate how geochemistry and substrate addition experiments can be complementary for the determination of the processes favored at these continental sites of serpentinization.
Mora, M.; Skiles, R.; McKinney, B.; Paredes, M.; Buckler, D.; Papoulias, D.; Klein, D.
2002-01-01
Peregrine falcons (Falco peregrinus) have been recorded nesting in Big Bend National Park, Texas, USA and other areas of the Chihuahuan Desert since the early 1900s. From 1993 to 1996, peregrine falcon productivity rates were very low and coincided with periods of low rainfall. However, low productivity also was suspected to be caused by environmental contaminants. To evaluate potential impacts of contaminants on peregrine falcon populations, likely avian and bat prey species were collected during 1994 and 1997 breeding seasons in selected regions of western Texas, primarily in Big Bend National Park. Tissues of three peregrine falcons found injured or dead and feathers of one live fledgling also were analyzed. Overall, mean concentrations of DDE [1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene], a metabolite of DDT [1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane], were low in all prey species except for northern rough-winged swallows (Stelgidopteryx serripennis, mean = 5.1 microg/g ww). Concentrations of mercury and selenium were elevated in some species, up to 2.5 microg/g dw, and 15 microg/g dw, respectively, which upon consumption could seriously affect reproduction of top predators. DDE levels near 5 microg/g ww were detected in carcass of one peregrine falcon found dead but the cause of death was unknown. Mercury, selenium, and DDE to some extent, may be contributing to low reproductive rates of peregrine falcons in the Big Bend region.
Synthetic Pot: Not Your Grandfather's Marijuana.
Ford, Benjamin M; Tai, Sherrica; Fantegrossi, William E; Prather, Paul L
2017-03-01
In the early 2000s in Europe and shortly thereafter in the USA, it was reported that 'legal' forms of marijuana were being sold under the name K2 and/or Spice. Active ingredients in K2/Spice products were determined to be synthetic cannabinoids (SCBs), producing psychotropic actions via CB 1 cannabinoid receptors, similar to those of Δ 9 -tetrahydrocannabinol (Δ 9 -THC), the primary active constituent in marijuana. Often abused by adolescents and military personnel to elude detection in drug tests due to their lack of structural similarity to Δ 9 -THC, SCBs are falsely marketed as safe marijuana substitutes. Instead, SCBs are a highly structural diverse group of compounds, easily synthesized, which produce very dangerous adverse effects occurring by, as of yet, unknown mechanisms. Therefore, available evidence indicates that K2/Spice products are clearly not safe marijuana alternatives. Copyright © 2016 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Bezrodny, V. G.; Watkins, B.; Charkina, O. V.; Yampolski, Y. M.
2014-03-01
The aim of the work is to experimentally investigate the response of scintillation spectra and indices of discrete cosmic sources (DCS) to modification of the ionospheric F-region by powerful electromagnetic fields with frequencies exceeding the Langmuir and upper hybrid ones. The results of a special experiment on the scintillations of radiation from DCS Cygnus A observed with using the 64-beam imaging riometer located near the Gakona village (Alaska, USA) are here presented. The ionosphere was artificially disturbed by powerful HAARP heater. Under the studied conditions of nonresonant heating of the ionospheric plasma, an earlier unknown effect of reducing the level of DCS scintillation was discovered. The theoretical interpretation has been given for the discovered effect, which using allowed the proposed technique of solving the inverse problem (recovery deviations of average electron density and temperature in the modified region from their unperturbed values).
Pathophysiology and Treatment of Hyperhidrosis.
Fujimoto, Tomoko
2016-01-01
Primary focal hyperhidrosis is a disease of unknown cause with profuse perspiration of local sites (head, face, palms, soles of feet, and axillae) that adversely affects daily life. Guidelines have been proposed in the USA [
Flight, William George; Bright-Thomas, Rowland; Mutton, Kenneth; Webb, Kevin; Jones, Andrew
2011-01-01
The authors report the case of a 25-year-old patient with cystic fibrosis (CF) who developed pandemic influenza A/H1N1 during a visit to the USA in August 2010. The patient has severe CF lung disease and takes maintenance oral corticosteroids. The influenza virus was positive for the H275Y oseltamivir-resistance mutation despite the patient never having received oseltamivir. The patient has remained sputum-positive for over 4 months despite inhaled zanamivir therapy. This is the first reported case of transmission of oseltamivir-resistant H1N1 influenza to a patient with CF. The frequency of prolonged sputum carriage of pandemic influenza and transmission of oseltamivir-resistant strains are unknown on a population level. However, if our observations are replicated in other CF patients, they are potentially of considerable importance to clinical and infection-control practices in this patient group. PMID:22696672
Pregnancy related listeriosis: treatment and control.
Allerberger, Franz; Huhulescu, Steliana
2015-03-01
Listeriosis during pregnancy usually presents as an unremarkable febrile illness in the mother but can be fatal for the fetus and newborn. Reliable laboratory testing for early diagnosis is lacking. Serological antibody tests and bacteriological stool tests are not helpful since Listeria-specific antibodies and stool cultures yielding the organism can be found in healthy pregnant women. Because early diagnosis is difficult, diagnosis is usually made by culturing the pathogen from blood, cerebrospinal fluid, placenta or meconium. The mortality rate for fetal and newborn listeriosis remains approximately 20%. Two to three cases of pregnancy-associated listeriosis are reported annually in Austria among approximately 79,000 births, 20-30 cases are reported annually in Germany among approximately 680,000 births and 50-100 cases are reported annually in the USA among approximately 4 million births. Although Listeria infections in pregnancy are rare, they should be considered as a cause of fever of unknown origin during pregnancy.
A rapid and rational approach to generating isomorphous heavy-atom phasing derivatives.
Lu, Jinghua; Sun, Peter D
2014-09-01
In attempts to replace the conventional trial-and-error heavy-atom derivative search method with a rational approach, we previously defined heavy metal compound reactivity against peptide ligands. Here, we assembled a composite pH- and buffer-dependent peptide reactivity profile for each heavy metal compound to guide rational heavy-atom derivative search. When knowledge of the best-reacting heavy-atom compound is combined with mass spectrometry assisted derivatization, and with a quick-soak method to optimize phasing, it is likely that the traditional heavy-atom compounds could meet the demand of modern high-throughput X-ray crystallography. As an example, we applied this rational heavy-atom phasing approach to determine a previously unknown mouse serum amyloid A2 crystal structure. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
Sodium chloride and hypertension.
Huang, Y W
1997-09-01
The hypothesis that sodium chloride deficiency, and not its overuse, is prime cause of hypertension and arteriosclerosis is presented. In the author's home town--a farflung part of northern China--hypertension is a rare disease and arteriosclerosis is a virtually unknown condition. The average intake of sodium chloride for these people is > 30 g/day compared with the typical sodium chloride intake of 10-12 g per day in the USA. When the 10-12 g salt ingested is mixed with the average daily water intake (2100 ml), 0.47% to 0.57% saline mixture is produced, which is hypotonic to extracellular fluid in salt content. Thus sodium conservation becomes necessary. All the hormones and ions involved in sodium conservation are inducers of hypertension; these include aldosterone, angiotensin 11, glucocorticoids, catecholamine, and vasopression. Plus, potassium waste, induced under the influence of aldosterone excess, participates in the development of hypertension.
Papoulias, Diana M.; Schwarz, Matt S.; Mena, Lourdes
2013-01-01
Nebraska's Rainwater Basin (RWB) provides important wetland habitat for North American migratory birds. Concern exists that pesticide and nutrient runoff from surrounding row-crops enters wetlands degrading water quality and adversely affecting birds and wildlife. Frogs may be especially vulnerable. Plains leopard (Lithobates blairi) metamorphs from RWB wetlands with varying concentrations of pesticides were evaluated for a suite of biomarkers of exposure to endocrine active chemicals. Froglets had ovarian dysgenesis, high rates of testicular oocytes, and female-biased sex ratios however, there was no clear statistical association between pesticide concentrations and biomarkers. Data interpretation was hindered because timing and duration of exposures were unknown and due to an incomplete understanding of L. blairi sexual development. Emphasis is on describing the complex developmental biology of closely-related leopard frogs, how this understanding can explain RWB L. blairi anomalies, and the need for sampling at the appropriate life stage.
Avascular Necrosis of the Femoral Head.
Seijas, Roberto; Sallent, Andrea; Rivera, Eila; Ares, Oscar
2017-12-29
About 250000 patients are operated on annually for hip arthroplasty in the USA alone. Of this number, about 10% the cause of their osteoarthritis is the avascular necrosis of the femoral head. But the causes of necrosis are multiple and many of them are still unknown. That is why small advances in etiopathogenesis, diagnosis and treatment of different causes are very important in order to reduce the number of affected patients. It may seem that small changes, studies focused on the details of different diseases do not bring great changes to science, but it is these small changes that end up adding great evolutions in our knowledge. In addition, the changes of recent years, are not focused on our specialty in technical or anatomical evolutions exclusively, but are often based on biological bases, which is the branch that evolves more within trauma and orthopedics. That is why open and constant minds are what help us move forward.
Congenital transmission of Neospora caninum in white-tailed deer (Odocoileus virginianus).
Dubey, J P; Jenkins, M C; Kwok, O C H; Ferreira, L R; Choudhary, S; Verma, S K; Villena, I; Butler, E; Carstensen, M
2013-09-23
Neosporosis is an important cause of bovine abortion worldwide. Many aspects of transmission of Neospora caninum in nature are unknown. The white-tailed deer (Odocoileus virginianus) is considered one of the most important wildlife reservoirs of N. caninum in the USA. During the hunting seasons of 2008, 2009, and 2010, brains of 155 white-tailed deer fetuses were bioassayed in mice for protozoal isolation. Viable N. caninum (NcWTDMn1, NcWTDMn2) was isolated from the brains of two fetuses by bioassays in mice, and subsequent propagation in cell culture. Dams of these two infected fetuses had antibodies to N. caninum by Neospora agglutination test at 1:100 serum dilution. DNA obtained from culture-derived N. caninum tachyzoites of the two isolates with Nc5 PCR confirmed diagnosis. Results prove congenital transmission of N. caninum in the white tailed deer for the first time. Published by Elsevier B.V.
Jones, Marcus B; Montgomery, Christopher P; Boyle-Vavra, Susan; Shatzkes, Kenneth; Maybank, Rosslyn; Frank, Bryan C; Peterson, Scott N; Daum, Robert S
2014-12-19
Staphylococcus aureus is a human pathogen responsible for substantial morbidity and mortality through its ability to cause a number of human infections including bacteremia, pneumonia and soft tissue infections. Of great concern is the emergence and dissemination of methicillin-resistant Staphylococcus aureus strains (MRSA) that are resistant to nearly all β-lactams. The emergence of the USA300 MRSA genetic background among community associated S. aureus infections (CA-MRSA) in the USA was followed by the disappearance of USA400 CA-MRSA isolates. To gain a greater understanding of the potential fitness advantages and virulence capacity of S. aureus USA300 clones, we performed whole genome sequencing of 15 USA300 and 4 USA400 clinical isolates. A comparison of representative genomes of the USA300 and USA400 pulsotypes indicates a number of differences in mobile genome elements. We examined the in vitro gene expression profiles by microarray hybridization and the in vivo transcriptomes during lung infection in mice of a USA300 and a USA400 MRSA strain by performing complete genome qRT-PCR analysis. The unique presence and increased expression of 6 exotoxins in USA300 (12- to 600-fold) compared to USA400 may contribute to the increased virulence of USA300 clones. Importantly, we also observed the up-regulation of prophage genes in USA300 (compared with USA400) during mouse lung infection (including genes encoded by both prophages ΦSa2usa and ΦSa3usa), suggesting that these prophages may play an important role in vivo by contributing to the elevated virulence characteristic of the USA300 clone. We observed differences in the genetic content of USA300 and USA400 strains, as well as significant differences of in vitro and in vivo gene expression of mobile elements in a lung pneumonia model. This is the first study to document the global transcription differences between USA300 and USA400 strains during both in vitro and in vivo growth.
Investigations on the Bundle Adjustment Results from Sfm-Based Software for Mapping Purposes
NASA Astrophysics Data System (ADS)
Lumban-Gaol, Y. A.; Murtiyoso, A.; Nugroho, B. H.
2018-05-01
Since its first inception, aerial photography has been used for topographic mapping. Large-scale aerial photography contributed to the creation of many of the topographic maps around the world. In Indonesia, a 2013 government directive on spatial management has re-stressed the need for topographic maps, with aerial photogrammetry providing the main method of acquisition. However, the large need to generate such maps is often limited by budgetary reasons. Today, SfM (Structure-from-Motion) offers quicker and less expensive solutions to this problem. However, considering the required precision for topographic missions, these solutions need to be assessed to see if they provide enough level of accuracy. In this paper, a popular SfM-based software Agisoft PhotoScan is used to perform bundle adjustment on a set of large-scale aerial images. The aim of the paper is to compare its bundle adjustment results with those generated by more classical photogrammetric software, namely Trimble Inpho and ERDAS IMAGINE. Furthermore, in order to provide more bundle adjustment statistics to be compared, the Damped Bundle Adjustment Toolbox (DBAT) was also used to reprocess the PhotoScan project. Results show that PhotoScan results are less stable than those generated by the two photogrammetric software programmes. This translates to lower accuracy, which may impact the final photogrammetric product.
Emergency Response Imagery Related to Hurricanes Harvey, Irma, and Maria
NASA Astrophysics Data System (ADS)
Worthem, A. V.; Madore, B.; Imahori, G.; Woolard, J.; Sellars, J.; Halbach, A.; Helmricks, D.; Quarrick, J.
2017-12-01
NOAA's National Geodetic Survey (NGS) and Remote Sensing Division acquired and rapidly disseminated emergency response imagery related to the three recent hurricanes Harvey, Irma, and Maria. Aerial imagery was collected using a Trimble Digital Sensor System, a high-resolution digital camera, by means of NOAA's King Air 350ER and DeHavilland Twin Otter (DHC-6) Aircraft. The emergency response images are used to assess the before and after effects of the hurricanes' damage. The imagery aids emergency responders, such as FEMA, Coast Guard, and other state and local governments, in developing recovery strategies and efforts by prioritizing areas most affected and distributing appropriate resources. Collected imagery is also used to provide damage assessment for use in long-term recovery and rebuilding efforts. Additionally, the imagery allows for those evacuated persons to see images of their homes and neighborhoods remotely. Each of the individual images are processed through ortho-rectification and merged into a uniform mosaic image. These remotely sensed datasets are publically available, and often used by web-based map servers as well as, federal, state, and local government agencies. This poster will show the imagery collected for these three hurricanes and the processes involved in getting data quickly into the hands of those that need it most.
NASA Astrophysics Data System (ADS)
2009-10-01
Science Organising Committee (SOC) Bruce Allen, AEI, Germany Patrick Brady, University of Wisconsin Milwaukee, USA Deepto Chakrabarty, MIT, USA Eugenio Coccia, INFN, Gran Sasso, Italy James Cordes, Cornell University, USA Mario Díaz (Chair), University of Texas Brownsville, USA Sam Finn, Penn State, USA Neil Gehrels, NASA GSFC, USA Fredrick A Jenet, University of Texas Brownsville, USA Nobuyuki Kanda, Osaka City University, Japan Erik Katsavounides, MIT, USA Dick Manchester, ATNF, Australia Soumya Mohanty, University of Texas Brownsville, USA Benoit Mours, LAPP-Annecy, France Maria Alessandra Papa, AEI, Germany Kate Scholberg, Duke University, USA Susan Scott, The Australian National University Alberto Vecchio, University of Birmingham, UK Andrea Vicere, INFN - Sezione di Firenze, Italy Stan Whitcomb, LIGO CALTECH, USA Local Organising Committee (LOC) Paulo Freire (Arecibo Observatory, Puerto Rico) Murray Lewis (Arecibo Observatory, Puerto Rico) Wanda Wiley (University of Texas Brownsville, USA)
George, Gavin; Rhodes, Bruce
2017-10-19
International migration is one of the factors resulting in the shortage of Human Resources for Health (HRH) in India. Literature suggests that migration is fuelled by the prospect of higher salaries available abroad. The extent of these salary differentials are unknown, and this study seeks to examine the salaries of selected HRH in India and four popular destination countries (United States of America, United Kingdom, Canada and the United Arab Emirates), whilst accounting for the in-country cost of living. This study will therefore determine truer financial incentives for Indian HRH to migrate abroad. A purchasing power parity (PPP) ratio is employed to equalise the international price of buying a representative basket of commonly bought goods (including food, entertainment, fuel and utilities). Using the PPP index, real differences in salaries are directly compared for selected work categories and different levels of work experience in the four respective countries. Nurses in the USA can earn up to 82.7% more than their Indian counterparts. Nurses in Canada and the UAE reveal more modest salary differentials, yet still significant better off by up to 28 and 20% respectively. Only nurses in the UK are potentially materially worse off than nurses working in India. We observe significant potential PPP gains of up to 57.4, 99.1 and 94.4% for medical doctors in the USA, Canada and the UAE respectively. Medical specialists potentially experience the greatest income disparities with anaesthetists potentially earning up to 600% more than their counterparts in India. Radiologists operating in the UK and general surgeons working in the USA can potentially earn more than double that of their counterparts working in India. We observe more modest positive or negligible PPP gains in other selected countries for health specialists. Even when considering the differences in the cost of living, the financial incentive for selected cadres of Indian HRH to seek work abroad remains strong. The migration of Indian HRH to countries offering superior salaries makes it difficult for India to retain experienced health personal and compromises government efforts to render health care more accessible across the country.
Geogenic organic contaminants in the low-rank coal-bearing Carrizo-Wilcox aquifer of East Texas, USA
Chakraborty, Jayeeta; Varonka, Matthew S.; Orem, William H.; Finkelman, Robert B.; Manton, William
2017-01-01
The organic composition of groundwater along the Carrizo-Wilcox aquifer in East Texas (USA), sampled from rural wells in May and September 2015, was examined as part of a larger study of the potential health and environmental effects of organic compounds derived from low-rank coals. The quality of water from the low-rank coal-bearing Carrizo-Wilcox aquifer is a potential environmental concern and no detailed studies of the organic compounds in this aquifer have been published. Organic compounds identified in the water samples included: aliphatics and their fatty acid derivatives, phenols, biphenyls, N-, O-, and S-containing heterocyclic compounds, polycyclic aromatic hydrocarbons (PAHs), aromatic amines, and phthalates. Many of the identified organic compounds (aliphatics, phenols, heterocyclic compounds, PAHs) are geogenic and originated from groundwater leaching of young and unmetamorphosed low-rank coals. Estimated concentrations of individual compounds ranged from about 3.9 to 0.01 μg/L. In many rural areas in East Texas, coal strata provide aquifers for drinking water wells. Organic compounds observed in groundwater are likely to be present in drinking water supplied from wells that penetrate the coal. Some of the organic compounds identified in the water samples are potentially toxic to humans, but at the estimated levels in these samples, the compounds are unlikely to cause acute health problems. The human health effects of low-level chronic exposure to coal-derived organic compounds in drinking water in East Texas are currently unknown, and continuing studies will evaluate possible toxicity.
Ecotypic variation in population dynamics of reintroduced bighorn sheep
Bleich, Vernon C.; Sargeant, Glen A.; Wiedmann, Brett P.
2018-01-01
Selection of bighorn sheep (Ovis canadensis) for translocation historically has been motivated by preservation of subspecific purity rather than by adaptation of source stocks to similar environments. Our objective was to estimate cause‐specific, annual, and age‐specific mortality of introduced bighorn sheep that originated at low elevations in southern British Columbia, Canada (BC ecotype), or in the Missouri River Breaks region of central Montana, USA (MT ecotype). In North Dakota, USA, mortality was similar and typically low for adult female bighorn sheep from Montana (0.09 ± 0.029 [SE]) and British Columbia (0.08 ± 0.017) during 2000–2016. Median life expectancy was 11 years for females that reached adulthood (2 yrs old); however, mortality accelerated with age and reached 86% by age 16. Mortalities resulted primarily from low rates of predation, disease, accidents, and unknown natural causes (<0.04 [upper 90% CI]). Similar survival rates of female bighorn sheep from female bighorn sheep from British Columbia and Montana, coupled with greater recruitment of bighorn sheep from Montana, resulted in a greater projected rate of increase for the MT ecotype (λ = 1.21) than for the BC ecotype (1.02), and a more youthful age structure. These results support translocation of bighorn sheep from areas that are environmentally similar to areas that will be stocked. Potential benefits include more rapid population growth, greater resilience to and more rapid recovery from density‐independent losses, an increased possibility that rapidly growing populations will expand into adjacent habitat, increased hunter opportunity, increased connectivity among herds, and a more complete restoration of ecosystem processes.
Custer, Christine M.; Custer, T.W.
2000-01-01
Because of the potential for increased trophic transfer of contaminants by zebra mussels (Dreissena sp.) to higher trophic levels, we collected four species of waterfowl (n = 65 ducks) from four locations in Lake Erie, Lake St. Clair, and Lake Michigan, USA, between 1991 and 1993 for organochlorine contaminant and trace element analyses. Geometric mean concentrations of total polychlorinated biphenyls (PCBs) and p,pa??-dichlorodiphenyldichloroethylene (DDE) were 1.35 and 0.15 I?g/g wet weight in lesser scaup (Aythya affinis) carcasses and were below known effect levels. Total PCBs in 80% of carcasses, however, were above the U.S. Food and Drug Administration's threshold of 3.0 I?g/g lipid weight for consumption of poultry. With the exception of selenium, trace elements were also at background or no-effect levels. Selenium concentrations in livers of 95% of lesser scaup, 90% of bufflehead (Bucephala albeola), and 72% of common goldeneye (Bucephala clangula) were in the elevated (>10 I?g/g dry wt) or potentially harmful range (>33 I?g/g dry wt). The effects of these high selenium concentrations are unknown but should be investigated further based on reproductive effects observed in field and laboratory studies of dabbling ducks and because lesser scaup populations are declining. Concentrations of total PCBs in dreissenid mussels in western Lake Erie were 10 times higher than in the upper Mississippi River but were similar to concentrations in other industrialized rivers in Europe and the United States. Metal concentrations were similar to other industrialized sites where zebra mussels have been sampled.
A possible cause of Alzheimer's dementia - industrial soy foods.
Roccisano, D; Henneberg, M; Saniotis, A
2014-03-01
Alzheimer's data indicate that at present, approximately one new case of this form of dementia is identified in the USA every 68 s and that by 2050 the incidence will be about every 33 s, with projections from the Alzheimer Association (USA) indicating that nearly 25% of Americans will be affected by Alzheimer's dementia by 2031. Despite the numerous advances in medical science and neurological research, the causes are still unknown and the incidence is not decreasing or levelling out. Most research on the causes of Alzheimer's dementia indicates the possible roles of viruses, obesity, physical inactivity, diabetes, psychological depression, high blood pressure, frequent inflammation, environmental or domestic chemicals and toxins, or inescapable genetic factors. Alzheimer's, being the degeneration of parts of the neural pathways in the brain, may indeed involve neuro-toxic compounds that can bypass the blood-brain barrier. Therefore, it is necessary to examine what is prolific in the environment and, in particular, the food supply. One of the many suggestions in the literature is the ingestion of food items derived from unfermented soybean products; the anti-thyroid, anti-nutrient, and endocrine disruption properties of soy can have a deleterious effect in many individuals. Among the many theories and different factors that may be involved in dementiae, soy consumption may be a significant contributor to Alzheimer's dementia, and it cannot be excluded as a possible contributing cause. Our hypothesis argues that consumption of soy food products may contribute to the increasing incidence of Alzheimer's dementia and other dementiae. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.
Rosenberry, Donald O.; Briggs, Martin A.; Voytek, Emily B.; Lane, John W.
2016-01-01
The remaining populations of the endangered dwarf wedgemussel (DWM) (Alasmidonta heterodon) in the upper Delaware River, northeastern USA, were hypothesized to be located in areas of greater-than-normal groundwater discharge to the river. We combined physical (seepage meters, monitoring wells and piezometers), thermal (fiber-optic distributed temperature sensing, infrared, vertical bed-temperature profiling), and geophysical (electromagnetic-induction) methods at several spatial scales to characterize known DWM habitat and explore this hypothesis. Numerous springs were observed using visible and infrared imaging along the river banks at all three known DWM-populated areas, but not in adjacent areas where DWM were absent. Vertical and lateral groundwater gradients were toward the river along all three DWM-populated reaches, with median upward gradients 3 to 9 times larger than in adjacent reaches. Point-scale seepage-meter measurements indicated that upward seepage across the riverbed was faster and more consistently upward at DWM-populated areas. Discrete and areally distributed riverbed-temperature measurements indicated numerous cold areas of groundwater discharge during warm summer months; all were within areas populated by DWM. Electromagnetic-induction measurements, which may indicate riverbed geology, showed patterning but little correlation between bulk streambed electromagnetic conductivity and areal distribution of DWM. In spite of complexity introduced by hyporheic exchange, multiple lines of research provide strong evidence that DWM are located within or directly downstream of areas of substantial focused groundwater discharge to the river. Broad scale thermal-reconnaissance methods (e.g., infrared) may be useful in locating and protecting other currently unknown mussel populations.
Public perceptions of cooking and the implications for cooking behaviour in the USA.
Wolfson, Julia A; Smith, Katherine Clegg; Frattaroli, Shannon; Bleich, Sara N
2016-06-01
Despite the importance of cooking in modern life, public perceptions about what it means to cook are unknown. We aimed to examine perceptions of cooking and their association with cooking confidence, attitudes and behaviours in the USA. We designed and fielded a nationally representative survey among US adults (n 1112) in April 2015. We used factor analysis to identify perceptions about cooking and multivariate ordered logit and Poisson models to explore associations between those perceptions and cooking confidence, attitudes and behaviours. Nationally representative web-based survey of US adults. US adults aged ≥18 years. Americans conceptualized cooking in three ways: the use of scratch ingredients, convenience foods and not using heat. Respondents who perceived cooking as including convenience foods were less confident in their ability to cook from scratch (OR=0·52, P<0·001) and less likely to enjoy cooking (OR=0·68, P=0·01) than those who did not. Although individuals who perceived cooking as including only scratch ingredients reported cooking dinner (4·31 times/week) and using packaged/boxed products (0·95 times/week) the least frequently, few notable differences in the frequency of cooking meals were observed. Cooking frequency is similar among US adults regardless of how they perceive cooking, but cooking confidence and enjoyment are lowest among Americans who perceive cooking as including the use of convenience foods. These insights should inform the development of more specific measures of cooking behaviour as well as meaningful and targeted public health messages to encourage healthier cooking.
Tomalia, Donald A
2012-07-01
Donald Tomalia received his Bachelor of Arts degree in Chemistry from the University of Michigan (MI, USA). He received his PhD in physical-organic Chemistry from Michigan State University (MI, USA) in 1968 while working at The Dow Chemical Company (MI, USA). In 1990 he moved to Michigan Molecular Institute (MI, USA) as Professor and Director of Nanoscale Chemistry and Architecture. He has subsequently founded three dendrimer based-nanotechnology companies, Dendritech, Inc. (MI, USA), Dendritic Nanotechnologies, Inc. (MI, USA) and NanoSynthons LLC (MI, USA). Donald Tomalia is currently Director of the National Dendrimer & Nanotechnology Center (MI, USA), CEO/founder of NanoSynthons LLC (MI, USA), distinguished visiting Professor, Columbia University (NY, USA) and affiliate Professor, Department of Physics, Virginia Commonwealth University (VA, USA). He is best known for his discovery of dendrimers and has received several awards for his accomplishments and contributions to science, including the 2012 Wallace H Carothers Award. He has authored over 250 publications, as well as over 128 patents.
NASA Astrophysics Data System (ADS)
Horta, João; Oliveira, Sónia; Moura, Delminda
2015-04-01
Future behaviour of beaches within a headland-beach system is of fundamental interest on coastal evolution since they act as a buffer between the waves' attack and the cliffs backing them. The beaches at the cliffs' foot anchored between headlands are space-limited environments to morphosedimentary processes. Additionally, headlands and shore platforms are natural barriers to the alongshore drift. Several attempts to develop numerical expressions to characterize the stability of headland-beach systems have been made based mainly on linear parameters. However, in the sandy areas occur volumetric variations of greater magnitude that changes in the shoreline position in a tidal cycle. This work aims to quantify the balance between the incoming and the lost sediment in two embayed beaches in order to improve knowledge of the sedimentary dynamics of such environments and therefore the evolution of coastal landscapes. The study area is the Algarve coastal karstic landscapes, which raises challenging questions on morphosedimentary processes because it has dozens of stacks and cavities both in the surf zone and in the nearshore that interfere with the littoral current patterns. The field campaigns were performed during spring tide conditions in February and March, 2011. The nearshore wave climate and the current's velocity and direction were measured using respectively a non-vented Level TROLL 700 Pressure Transducer (PT) and an autonomously deployable electro-magnetic current meter (EMCM) Infinity-EM with a data logger. The offshore wave data used was acquired through the Portuguese Hydrographic Institute (IH) at the Faro buoy, located 50 km southeast from the study area. The topographic surveys were performed for a total area of about 1500 m2 using two Global Navigation Satellite System receptors (GPS Trimble R6 and GPS Trimble 5800) in real-time kinematic mode (RTK) with differential global positioning system (DGPS) providing centimetric accuracy. The altimetric values ranged between -2 and +6 m (mean sea level-msl). The automatic determination of the spatial characteristics of the beach morphology results from the GIS tools. The wave and current post processing was made using the STWAVE and Bouss-2D model software. Our results showed that: (i) the shore orientation is the major factor for the height of the waves approaching the coast (considering the same offshore climate) and thus to the wave energy input to transport sediment, (ii) the shore platforms which extend up to -7 m (msl) determine a very irregular pattern of the shoaling waves and distance of the breaking point from the shoreline, (iii) as a consequence of (ii) the rip currents in the surf zone show a very complex pattern and the direction of the sedimentary transport can be opposite to the direction of the incoming waves, (iv) the pattern of the rip currents is highly variable depending on the water depth, (v) the results obtained for volumetric balances showed a negative balance (erosion higher than accretion) at the smaller embayed beach and a positive balance (accretion higher than erosion) at the larger one. This work is a contribution to the PTDC/GEO-GEO/3981/2012 funded by the Portuguese Foundation for Science and Technology.
NASA Astrophysics Data System (ADS)
2011-10-01
International Advisory Committee Richard F CastenYale, USA Luiz Carlos ChamonSão Paulo, Brazil Osvaldo CivitareseLa Plata, Argentina Jozsef CsehATOMKI, Hungary Jerry P DraayerLSU, USA Alfredo Galindo-UribarriORNL & UT, USA James J KolataNotre Dame, USA Jorge López UTEP, USA Joseph B NatowitzTexas A & M, USA Ma Esther Ortiz IF-UNAM Stuart PittelDelaware, USA Andrés SandovalIF-UNAM Adam SzczepaniakIndiana, USA Piet Van IsackerGANIL, France Michael WiescherNotre Dame, USA Organizing Committee Libertad Barrón-Palos (Chair)IF-UNAM Roelof BijkerICN-UNAM Ruben FossionICN-UNAM David LizcanoININ Sponsors Instituto de Ciencias Nucleares, UNAMInstituto de Física, UNAMInstituto Nacional de Investigaciones NuclearesDivisión de Física Nuclear de la SMFCentro Latinoamericano de Física
COMMITTEES: Quark Matter 2008 Organising and International Advisory Committees
NASA Astrophysics Data System (ADS)
2008-10-01
Organising Committee Madan M Aggarwal (Chandigarh) Jan-e Alam (Kolkata) Convener Arup Bandyopadhyay (Kolkata) Debades Bandyopadhyay (Kolkata) Rahul Basu (Chennai) Rakesh K Bhandari (Kolkata) Anju Bhasin (Jammu) Subhasis Chattopadhyay (Kolkata) Convener Sukalyan Chattopadhyay (Kolkata) Asis Chaudhuri (Kolkata) Premomoy Ghosh (Kolkata) Sanjay Ghosh (Kolkata) Sourendu Gupta (Mumbai) Muhammad Irfan (Aligarh) Durga P Mahapatra (Bhubaneswar) DAmruta Mishra (New Delhi) Ajit K Mohanty (Mumbai) Bedangadas Mohanty (Kolkata) Vaisali Naik (Kolkata) Tapan K Nayak (Kolkata) Convener Sudhir Raniwala (Jaipur) Sourav Sarkar (Kolkata) Bikash Sinha (Kolkata) Chair Dinesh Srivastava (Kolkata) Raghava Varma (Mumbai) Yogendra P Viyogi (Bhubaneswar)Co-chair International Advisory Committee R Aymar,Switzerland Jean Paul Blaizot, France Peter Braun Münzinger, Germany Igor M Dremin, Russia Kari Eskola, Finland Jens Jorgen Gaardhoje,Denmark Rajiv V Gavai, India Hans-Ake Gustaffson, Sweden Hans Gutbrod, Germany Miklos Gyulassy, USA Timothy Hallman, USA Hideki Hamagaki, Japan Tetsuo Hatsuda, Japan Huan-Zhong Huang, USA Barbara Jacak, USA Peter Jenni, Switzerland Taka Kajino, Japan Takeshi Kodama, Brazil T D Lee, USA Peter Levai, Hungary Luciano Maiani, Italy Larry McLerran, USA Berndt Müller, USA Guy Paic, Mexico Sibaji Raha, India Lodovico Riccati, Italy Hans Georg Ritter, USA Helmut Satz, Germany Jurgen Schukraft, Switzerland Yves Schutz, France Edward V Shuryak, USA Johanna Stachel, Germany Horst Stöcker, Germany Itzhak Tserruya, Israel Xin-Nian Wang, USA Bolek Wyslouch, USA Glenn R Young, USA William A Zajc, USA Wen-Long Zhan, China
2011-01-01
The mode of viral hemorrhagic septicemia virus (VHSV) transmission in the Great Lakes basin is largely unknown. In order to assess the potential role of macroinvertebrates in VHSV transmission, Diporeia spp., a group of amphipods that are preyed upon by a number of susceptible Great Lakes fishes, were collected from seven locations in four of the Great Lakes and analyzed for the presence of VHSV. It was demonstrated that VHSV is present in some Diporeia spp. samples collected from lakes Ontario, Huron, and Michigan, but not from Lake Superior. Phylogenetic comparison of partial nucleoprotein (N) gene sequences (737 base pairs) of the five isolates to sequences of 13 other VHSV strains showed the clustering of Diporeia spp. isolates with the VHSV genotype IVb. This study reports the first incidence of a fish-pathogenic rhabdovirus being isolated from Diporeia, or any other crustacean and underscores the role macroinvertebrates may play in VHSV ecology. PMID:21210995
Austin, Lauren V.; Silvis, Alexander; Ford, W. Mark; Muthersbaugh, Michael; Powers, Karen E.
2018-01-01
After decades of fire suppression in eastern North America, land managers now are prioritizing prescribed fire as a management tool to restore or maintain fire-adapted vegetation communities. However, in long—fire-suppressed landscapes, such as the central and southern Appalachians, it is unknown how bats will respond to prescribed fire in both riparian and upland forest habitats. To address these concerns, we conducted zero-crossing acoustic surveys of bat activity in burned, unburned, riparian, and non-riparian areas in the central Appalachians, Virginia, USA. Burn and riparian variables had model support (ΔAICc < 4) to explain activity of all bat species. Nonetheless, parameter estimates for these conditions were small and confidence intervals overlapped zero for all species, indicating effect sizes were marginal. Our results suggest that bats respond to fire differently between upland and riparian forest habitats, but overall, large landscape-level prescribed fire has a slightly positive to neutral impact on all bats species identified at our study site post—fire application.
Clayey Landslide Initiation and Acceleration Strongly Modulated by Soil Swelling
NASA Astrophysics Data System (ADS)
Schulz, William H.; Smith, Joel B.; Wang, Gonghui; Jiang, Yao; Roering, Joshua J.
2018-02-01
Largely unknown mechanisms restrain motion of clay-rich, slow-moving landslides that are widespread worldwide and rarely accelerate catastrophically. We studied a clayey, slow-moving landslide typical of thousands in Northern California, USA, to decipher hydrologic-mechanical interactions that modulate landslide dynamics. Similar to some other studies, observed pore-water pressures correlated poorly with landslide reactivation and speed. In situ and laboratory measurements strongly suggested that variable pressure along the landslide's lateral shear boundaries resulting from seasonal soil expansion and contraction modulated its reactivation and speed. Slope-stability modeling suggested that the landslide's observed behavior could be predicted by including transient swell pressure as a resistance term, whereas modeling considering only transient hydrologic conditions predicted movement five to six months prior to when it was observed. All clayey soils swell to some degree; hence, our findings suggest that swell pressure likely modulates motion of many landslides and should be considered to improve forecasts of clayey landslide initiation and mobility.
Clayey landslide initiation and acceleration strongly modulated by soil swelling
Schulz, William; Smith, Joel B.; Wang, Gonghui; Jiang, Yao; Roering, Joshua J.
2018-01-01
Largely unknown mechanisms restrain motion of clay-rich, slow-moving landslides that are widespread worldwide and rarely accelerate catastrophically. We studied a clayey, slow-moving landslide typical of thousands in northern California, USA, to decipher hydrologic-mechanical interactions that modulate landslide dynamics. Similar to some other studies, observed pore-water pressures correlated poorly with landslide reactivation and speed. In situ and laboratory measurements strongly suggested that variable pressure along the landslide's lateral shear boundaries resulting from seasonal soil expansion and contraction modulated its reactivation and speed. Slope-stability modeling suggested that the landslide's observed behavior could be predicted by including transient swell pressure as a resistance term, whereas modeling considering only transient hydrologic conditions predicted movement 5–6 months prior to when it was observed. All clayey soils swell to some degree; hence, our findings suggest that swell pressure likely modulates motion of many landslides and should be considered to improve forecasts of clayey landslide initiation and mobility.
Organochlorine contaminants and Tree Swallows along the Fox River and Green Bay, Wisconsin, USA
Custer, Christine M.; Custer, T.W.; Allen, P. David; Stromborg, K.L.; Melancon, M.J.; Adams, N.J.; Slotow, R.H.
1999-01-01
Green Bay, Wisconsin is contaminated with polychlorinated biphenyls (PCBs) however, whether these contaminants affect reproduction in insectivorous birds is unknown. Tree Swallows, Tachycineta bicolor, are secondary cavity nesters that will nest in boxes and tolerate handling. Because Tree Swallows are aquatic insectivores, residues in their tissues are primarily indicative of contaminants in sediments. We studied swallows at two contaminated and two reference colonies in 1993, 1994, and 1995 in the Green Bay area. Swallows at the two contaminated sites had significantly higher PCB levels in eggs when compared to two reference sites. Eggs from clutches that contained dead embryos had higher PCB concentrations than eggs from clutches where all eggs hatched; there were no contaminant effects overall on reproduction, however. Twelve-day-old nestlings at the two contaminated sites accumulated significantly more PCBs than did nestlings at the reference sites demonstrating that PCB contamination came from the local area. The PCB congener profile in 12-day-old nestlings mirrored the congener profile in their food.
The influence of endocrine disruptors on growth and development of children.
DiVall, Sara A
2013-02-01
This review describes the most recent data about the effects of endocrine disrupting compounds (EDCs) on infant and early childhood growth and reproductive tract development as well as controversies in the field. EDCs are present in pregnant women, young children and adolescents. Whether the level of exposure contributes to disease is an ongoing debate. Epidemiological studies suggest associations between prenatal EDC exposure and disease outcome, but animal studies using controlled EDC exposure have varying results with underlying mechanisms largely unknown. Human exposure to EDCs is widespread; bisphenol A, phthalates and persistent organic pollutants are detectable in all age groups and geographical locations in the USA. Epidemiological and animal studies suggest that phthalates and bisphenol A have adverse effects on birth weight, promote development of childhood obesity and adversely affect male reproductive tract development. Differences in the interpretation of available studies underlie the disparate conclusions of scientific and regulatory body's panels on potential toxicological effects of EDCs at current levels of human exposure.
From fantasy to reality: managing biomedical risk emotions in and through fictional media.
Cottingham, Marci D; Fisher, Jill A
2017-01-01
In this article, we explore the role that fictional media (film and television) play in evoking and managing collective and individual anxieties towards biomedical research. We draw on two data sets: fictional media depictions of human research subjects and interviews with Phase I clinical trial participants conducted in the USA in 2013. We show how fictional media provide an outlet for collective uncertainties surrounding biomedical research through depictions that mock and dehumanise research participants, using such emotions of shock, disgust, pity, amusement and humour. We analyse how themes from fictional media are also used to manage actual clinical trial participants' own anxiety concerning the unknown risks of research participation. By contrasting the reality of their research experience with fantasy derived from entertainment media, clinical trial participants minimise the seriousness of the side effects they have or may experience in actual Phase I clinical trials. We conclude that fictional media serve an important role in the collective and individual management of risk emotion.
Nesměrák, Karel; Kunešová, Jana
2015-06-01
The history of traditional capuchin balsam is the focal point of the second part of the article on the unknown history of pharmacy at the capuchin monastery in Prague-Hradčany. Capuchin balsam, a medicinal speciality, was being manufactured in the monastery from the end of the 18th century till the year 1950. It is a spirit tincture, its prescription originating from the formulation by Oswald Croll. Balsamum Peruvianum, Gummiresina myrrha, Gummiresina olibanum, and Styrax are the main ingredients, besides assorted plants. The balsam was taken as an antiseptic, antiphlogistic, and analgesic. The balsam was a favoured rustic medicine, and it was sold also abroad (Germany, Poland, USA, Ireland, Belgium). The profit made from the sale of the balsam supported the reconstruction and the maintenance of the monastery and the local theological studies. Other medical formulations connected with the name of the capuchin order are also mentioned.Key words: pharmaceutical history capuchins capuchin balsam monastics pharmacies.
Zika Virus Infection in Patient with No Known Risk Factors, Utah, USA, 2016.
Krow-Lucal, Elisabeth R; Novosad, Shannon A; Dunn, Angela C; Brent, Carolyn R; Savage, Harry M; Faraji, Ary; Peterson, Dallin; Dibbs, Andrew; Vietor, Brook; Christensen, Kimberly; Laven, Janeen J; Godsey, Marvin S; Christensen, Bryan; Beyer, Brigette; Cortese, Margaret M; Johnson, Nina C; Panella, Amanda J; Biggerstaff, Brad J; Rubin, Michael; Fridkin, Scott K; Staples, J Erin; Nakashima, Allyn K
2017-08-01
In 2016, Zika virus disease developed in a man (patient A) who had no known risk factors beyond caring for a relative who died of this disease (index patient). We investigated the source of infection for patient A by surveying other family contacts, healthcare personnel, and community members, and testing samples for Zika virus. We identified 19 family contacts who had similar exposures to the index patient; 86 healthcare personnel had contact with the index patient, including 57 (66%) who had contact with body fluids. Of 218 community members interviewed, 28 (13%) reported signs/symptoms and 132 (61%) provided a sample. Except for patient A, no other persons tested had laboratory evidence of recent Zika virus infection. Of 5,875 mosquitoes collected, none were known vectors of Zika virus and all were negative for Zika virus. The mechanism of transmission to patient A remains unknown but was likely person-to-person contact with the index patient.
Sustainable water management under future uncertainty with eco-engineering decision scaling
NASA Astrophysics Data System (ADS)
Poff, N. Leroy; Brown, Casey M.; Grantham, Theodore E.; Matthews, John H.; Palmer, Margaret A.; Spence, Caitlin M.; Wilby, Robert L.; Haasnoot, Marjolijn; Mendoza, Guillermo F.; Dominique, Kathleen C.; Baeza, Andres
2016-01-01
Managing freshwater resources sustainably under future climatic and hydrological uncertainty poses novel challenges. Rehabilitation of ageing infrastructure and construction of new dams are widely viewed as solutions to diminish climate risk, but attaining the broad goal of freshwater sustainability will require expansion of the prevailing water resources management paradigm beyond narrow economic criteria to include socially valued ecosystem functions and services. We introduce a new decision framework, eco-engineering decision scaling (EEDS), that explicitly and quantitatively explores trade-offs in stakeholder-defined engineering and ecological performance metrics across a range of possible management actions under unknown future hydrological and climate states. We illustrate its potential application through a hypothetical case study of the Iowa River, USA. EEDS holds promise as a powerful framework for operationalizing freshwater sustainability under future hydrological uncertainty by fostering collaboration across historically conflicting perspectives of water resource engineering and river conservation ecology to design and operate water infrastructure for social and environmental benefits.
Update on the Mechanisms of Liver Regeneration.
Preziosi, Morgan E; Monga, Satdarshan P
2017-05-01
Liver possesses many critical functions such as synthesis, detoxification, and metabolism. It continually receives nutrient-rich blood from gut, which incidentally is also toxin-rich. That may be why liver is uniquely bestowed with a capacity to regenerate. A commonly studied procedure to understand the cellular and molecular basis of liver regeneration is that of surgical resection. Removal of two-thirds of the liver in rodents or patients instigates alterations in hepatic homeostasis, which are sensed by the deficient organ to drive the restoration process. Although the exact mechanisms that initiate regeneration are unknown, alterations in hemodynamics and metabolism have been suspected as important effectors. Key signaling pathways are activated that drive cell proliferation in various hepatic cell types through autocrine and paracrine mechanisms. Once the prehepatectomy mass is regained, the process of regeneration is adequately terminated. This review highlights recent discoveries in the cellular and molecular basis of liver regeneration. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Undiagnosed MODY: Time for Action.
Kleinberger, Jeffrey W; Pollin, Toni I
2015-12-01
Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes that accounts for at least 1 % of all cases of diabetes mellitus. MODY classically presents as non-insulin-requiring diabetes in lean individuals typically younger than 25 with evidence of autosomal dominant inheritance, but these criteria do not capture all cases and can also overlap with other diabetes types. Genetic diagnosis of MODY is important for selecting the right treatment, yet ~95 % of MODY cases in the USA are misdiagnosed. MODY prevalence and characteristics have been well-studied in some populations, such as the UK and Norway, while other ethnicities, like African and Latino, need much more study. Emerging next-generation sequencing methods are making more widespread study and clinical diagnosis increasingly feasible; at the same time, they are detecting other mutations in the same genes of unknown clinical significance. This review will cover the current epidemiological studies of MODY and barriers and opportunities for moving toward a goal of access to an appropriate diagnosis for all affected individuals.
The Meaning of Patient Empowerment in the Digital Age: The Role of Online Patient-Communities.
Lamas, Eugenia; Salinas, Rodrigo; Coquedano, Carla; Simon, Marie-Pierre; Bousquet, Cedric; Ferrer, Marcela; Zorrilla, Sergio
2017-01-01
Traditionally, patient empowerment has been used as a strategy for health promotion. The rise of online communities of patients represents a good example of how patient empowerment occurs, independently of the intervention of existing healthcare providers and insurers, allowing thus a more accurate definition of meaning of this concept. We describe two situations related with the development of health-related social networks: (1) The emergence of a new biomedical research model in which patients lead research, shifting the equilibrium of power from the professionals to research subjects themselves, and (2) The emergence of Lay Crowd-Sourced Expertise in these communities, arising from the daily exchange among patients affected by chronic conditions and their relatives, giving place to a new era of bottom-up data generation, previously unknown in biomedical sciences. We enrich these descriptions by analyzing interviews to key actors of these "on line" communities": Michael Chekroun, founder of "Carenity, France", and Paul Wicks Vice President at "PatientsLikeMe, USA".
Effects of Invasive Winter Moth Defoliation on Tree Radial Growth in Eastern Massachusetts, USA
Simmons, Michael J.; Lee, Thomas D.; Ducey, Mark J.; Elkinton, Joseph S.; Boettner, George H.; Dodds, Kevin J.
2014-01-01
Winter moth, Operophtera brumata L. (Lepidoptera: Geometridae), has been defoliating hardwood trees in eastern Massachusetts since the 1990s. Native to Europe, winter moth has also been detected in Rhode Island, Connecticut, eastern Long Island (NY), New Hampshire, and Maine. Individual tree impacts of winter moth defoliation in New England are currently unknown. Using dendroecological techniques, this study related annual radial growth of individual host (Quercus spp. and Acer spp.) trees to detailed defoliation estimates. Winter moth defoliation was associated with up to a 47% reduction in annual radial growth of Quercus trees. Latewood production of Quercus was reduced by up to 67% in the same year as defoliation, while earlywood production was reduced by up to 24% in the year following defoliation. Winter moth defoliation was not a strong predictor of radial growth in Acer species. This study is the first to document impacts of novel invasions of winter moth into New England. PMID:26462685
2017-01-01
Ceratopsids (“horned dinosaurs”) are known from western North America and Asia, a distribution reflecting an inferred subaerial link between the two landmasses during the Late Cretaceous. However, this clade was previously unknown from eastern North America, presumably due to limited outcrop of the appropriate age and depositional environment as well as the separation of eastern and western North America by the Western Interior Seaway during much of the Late Cretaceous. A dentary tooth from the Owl Creek Formation (late Maastrichtian) of Union County, Mississippi, represents the first reported occurrence of Ceratopsidae from eastern North America. This tooth shows a combination of features typical of Ceratopsidae, including a double root and a prominent, blade-like carina. Based on the age of the fossil, we hypothesize that it is consistent with a dispersal of ceratopsids into eastern North America during the very latest Cretaceous, presumably after the two halves of North America were reunited following the retreat of the Western Interior Seaway. PMID:28560100
Compliance with the Healthy Eating Standards in YMCA afterschool programs
Beets, Michael W.; Weaver, R. Glenn; Turner-McGrievy, Brie; Beighle, Aaron; Moore, Justin B.; Webster, Collin; Khan, Mahmud; Saunders, Ruth
2016-01-01
Objective In 2011, the YMCA of the USA adopted Healthy Eating (HE) Standards for all their afterschool programs (ASPs). The extent to which YMCA-ASPs comply with the standards is unknown. Methods Twenty ASPs from all YMCA-ASPs across SC (N=102) were invited to participate. Direct observation of the foods/beverages served and staff behaviors were collected on four non-consecutive days/ASP. Results One ASP did not serve a snack. Of the remaining, a total of 26% ASPs served a fruit/vegetable and 32% served water every day; 26% served sugar-sweetened beverages, 47% served sugar-added foods, and only 11% served whole grains, when grains were served. Staff were sitting with the children (65%) or verbally promoting healthy eating (15%) on at least one observation day. Staff where drinking non-approved drinks (25%) or foods (45%) on at least one observation day. No ASPs served snacks family-style every day. Conclusions/Implications Additional efforts are required to assist YMCA-operated ASPs in achieving these important nutrition standards. PMID:27372234
Sustainable water management under future uncertainty with eco-engineering decision scaling
Poff, N LeRoy; Brown, Casey M; Grantham, Theodore E.; Matthews, John H; Palmer, Margaret A.; Spence, Caitlin M; Wilby, Robert L.; Haasnoot, Marjolijn; Mendoza, Guillermo F; Dominique, Kathleen C; Baeza, Andres
2015-01-01
Managing freshwater resources sustainably under future climatic and hydrological uncertainty poses novel challenges. Rehabilitation of ageing infrastructure and construction of new dams are widely viewed as solutions to diminish climate risk, but attaining the broad goal of freshwater sustainability will require expansion of the prevailing water resources management paradigm beyond narrow economic criteria to include socially valued ecosystem functions and services. We introduce a new decision framework, eco-engineering decision scaling (EEDS), that explicitly and quantitatively explores trade-offs in stakeholder-defined engineering and ecological performance metrics across a range of possible management actions under unknown future hydrological and climate states. We illustrate its potential application through a hypothetical case study of the Iowa River, USA. EEDS holds promise as a powerful framework for operationalizing freshwater sustainability under future hydrological uncertainty by fostering collaboration across historically conflicting perspectives of water resource engineering and river conservation ecology to design and operate water infrastructure for social and environmental benefits.
Farke, Andrew A; Phillips, George E
2017-01-01
Ceratopsids ("horned dinosaurs") are known from western North America and Asia, a distribution reflecting an inferred subaerial link between the two landmasses during the Late Cretaceous. However, this clade was previously unknown from eastern North America, presumably due to limited outcrop of the appropriate age and depositional environment as well as the separation of eastern and western North America by the Western Interior Seaway during much of the Late Cretaceous. A dentary tooth from the Owl Creek Formation (late Maastrichtian) of Union County, Mississippi, represents the first reported occurrence of Ceratopsidae from eastern North America. This tooth shows a combination of features typical of Ceratopsidae, including a double root and a prominent, blade-like carina. Based on the age of the fossil, we hypothesize that it is consistent with a dispersal of ceratopsids into eastern North America during the very latest Cretaceous, presumably after the two halves of North America were reunited following the retreat of the Western Interior Seaway.
The criminal purchase of firearm ammunition.
Tita, G E; Braga, A A; Ridgeway, G; Pierce, G L
2006-10-01
Laws that prohibit certain individuals from owning firearms also pertain to ammunition. Whereas retail sales of firearms to criminals are regularly disrupted by instant background checks, sales of ammunition are essentially unchecked and the rate at which criminals acquire ammunition is unknown. This research describes the ammunition market and estimates the rate at which criminals are acquiring ammunition. Criminal background checks conducted on individuals purchasing ammunition in the City of Los Angeles in April and May 2004. Los Angeles, CA, USA. Ammunition purchasers. Criminal activity that prohibits one from owning, purchasing, or possessing ammunition. 2.6% (95% CI 1.9% to 3.2%) of ammunition purchasers had a prior felony conviction or another condition that prohibited them from possessing ammunition. During the study period prohibited possessors purchased 10,050 rounds of ammunition in Los Angeles. These estimates suggest that monitoring ammunition transactions may help reduce the supply of ammunition to criminals and the frequency of injuries from felonious gun assaults. Such a record can also provide information for generating leads on illegal firearm possession.
Zika Virus Infection in Patient with No Known Risk Factors, Utah, USA, 2016
Krow-Lucal, Elisabeth R.; Novosad, Shannon A.; Dunn, Angela C.; Brent, Carolyn R.; Savage, Harry M.; Faraji, Ary; Peterson, Dallin; Dibbs, Andrew; Vietor, Brook; Christensen, Kimberly; Laven, Janeen J.; Godsey, Marvin S.; Christensen, Bryan; Beyer, Brigette; Cortese, Margaret M.; Johnson, Nina C.; Panella, Amanda J.; Biggerstaff, Brad J.; Rubin, Michael; Fridkin, Scott K.; Nakashima, Allyn K.
2017-01-01
In 2016, Zika virus disease developed in a man (patient A) who had no known risk factors beyond caring for a relative who died of this disease (index patient). We investigated the source of infection for patient A by surveying other family contacts, healthcare personnel, and community members, and testing samples for Zika virus. We identified 19 family contacts who had similar exposures to the index patient; 86 healthcare personnel had contact with the index patient, including 57 (66%) who had contact with body fluids. Of 218 community members interviewed, 28 (13%) reported signs/symptoms and 132 (61%) provided a sample. Except for patient A, no other persons tested had laboratory evidence of recent Zika virus infection. Of 5,875 mosquitoes collected, none were known vectors of Zika virus and all were negative for Zika virus. The mechanism of transmission to patient A remains unknown but was likely person-to-person contact with the index patient. PMID:28726601
Scott, Clinton T.; Slack, John F.; Kelley, Karen Duttweiler
2017-01-01
Black shales of the Late Devonian to Early Mississippian Bakken Formation are characterized by high concentrations of organic carbon and the hyper-enrichment (> 500 to 1000s of mg/kg) of V and Zn. Deposition of black shales resulted from shallow seafloor depths that promoted rapid development of euxinic conditions. Vanadium hyper-enrichments, which are unknown in modern environments, are likely the result of very high levels of dissolved H2S (~ 10 mM) in bottom waters or sediments. Because modern hyper-enrichments of Zn are documented only in Framvaren Fjord (Norway), it is likely that the biogeochemical trigger responsible for Zn hyper-enrichment in Framvaren Fjord was also present in the Bakken basin. With Framvaren Fjord as an analogue, we propose a causal link between the activity of phototrophic sulfide oxidizing bacteria, related to the development of photic-zone euxinia, and the hyper-enrichment of Zn in black shales of the Bakken Formation.
Extraordinary phylogenetic diversity and metabolic versatility in aquifer sediment
Castelle, Cindy J.; Hug, Laura A.; Wrighton, Kelly C.; ...
2013-08-27
Microorganisms in the subsurface represent a substantial but poorly understood component of the Earth’s biosphere. Subsurface environments are complex and difficult to characterize; thus, their microbiota have remained as a ‘dark matter’ of the carbon and other biogeochemical cycles. Here we deeply sequence two sediment-hosted microbial communities from an aquifer adjacent to the Colorado River, CO, USA. No single organism represents more than ~1% of either community. Remarkably, many bacteria and archaea in these communities are novel at the phylum level or belong to phyla lacking a sequenced representative. The dominant organism in deeper sediment, RBG-1, is a member ofmore » a new phylum. On the basis of its reconstructed complete genome, RBG-1 is metabolically versatile. Its wide respiration-based repertoire may enable it to respond to the fluctuating redox environment close to the water table. We document extraordinary microbial novelty and the importance of previously unknown lineages in sediment biogeochemical transformations.« less
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2011-09-23
... Medical Solutions USA, Inc., Oncology Care Systems Division, Concord, CA; Siemens Medical Solutions USA... Solutions USA, Inc. (Siemens), Oncology Care Systems Division, Concord, California (subject firm). The...., Oncology Care Systems Division, Concord, California (TA-W-73,158) and Siemens Medical Solutions USA, Inc...
Formation of Ground Truth Databases and Related Studies and Regional Seismic Monitoring Research
2006-06-01
denoted by black circles) and those derived by the combined use of both IRIS and revised IDC for all 70 Chinese events. Arrows point towards the...IRIS data provide a large number of additional Lg amvals. Figure 45. Differences in epicentral location between the original REB (denoted by black ...Washington, USA Haystack Fork , Wyoming, USA Hells Canyon, Colorado, USA Hiawatha Road, Colorado, USA Hockley, Texas, USA Hailey, Idaho, USA Honiara
Whitman, Timothy J; Schlett, Carey D; Grandits, Greg A; Millar, Eugene V; Mende, Katrin; Hospenthal, Duane R; Murray, Patrick R; Tribble, David R
2012-08-01
Methicillin-resistant Staphylococcus aureus (MRSA) pulsed-field type (PFT) USA300 causes skin and soft tissue infections in military recruits and invasive disease in hospitals. Chlorhexidine gluconate (CHG) is used to reduce MRSA colonization and infection. The impact of CHG on the molecular epidemiology of MRSA is not known. To evaluate the impact of 2% CHG-impregnated cloths on the molecular epidemiology of MRSA colonization. Cluster-randomized, double-blind, controlled trial. Marine Officer Candidate School, Quantico, Virginia, in 2007. Military recruits. Thrice-weekly application of CHG-impregnated or control (Comfort Bath; Sage) cloths over the entire body. Baseline and serial (every 2 weeks) nasal and/or axillary swab samples were assessed for MRSA colonization. Molecular analysis was performed with pulsed-field gel electrophoresis. During training, 77 subjects (4.9%) acquired MRSA, 26 (3.3%) in the CHG group and 51 (6.5%) in the control group (P=.004). When analyzed for PFT, 24 subjects (3.1%) in the control group but only 6 subjects (0.8%) in the CHG group (P=.001) had USA300. Of the 167 colonizing isolates recovered from 77 subjects, 99 were recovered from the control group, including USA300 (40.4%), USA800 (38.4%), USA1000 (12.1%), and USA100 (6.1%), and 68 were recovered from the CHG group, including USA800 (51.5%), USA100 (23.5%), and USA300 (13.2%). CHG decreased the transmission of MRSA--more specifically, USA300--among military recruits. In addition, USA300 and USA800 outcompeted other MRSA PFTs at incident colonization. Future studies should evaluate the broad-based use of CHG to decrease transmission of USA300 in hospital settings.
Whitman, Timothy J.; Schlett, Carey D.; Grandits, Greg A.; Millar, Eugene V.; Mende, Katrin; Hospenthal, Duane R.; Murray, Patrick R.; Tribble, David R.
2018-01-01
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) pulsed-field type (PFT) USA300 causes skin and soft tissue infections in military recruits and invasive disease in hospitals. Chlorhexidine gluconate (CHG) is used to reduce MRSA colonization and infection. The impact of CHG on the molecular epidemiology of MRSA is not known. OBJECTIVE To evaluate the impact of 2% CHG–impregnated cloths on the molecular epidemiology of MRSA colonization. DESIGN Cluster-randomized, double-blind, controlled trial. SETTING Marine Officer Candidate School, Quantico, Virginia, in 2007. PARTICIPANTS Military recruits. INTERVENTION Thrice-weekly application of CHG-impregnated or control (Comfort Bath; Sage) cloths over the entire body. MEASUREMENTS Baseline and serial (every 2 weeks) nasal and/or axillary swab samples were assessed for MRSA colonization. Molecular analysis was performed with pulsed-field gel electrophoresis. RESULTS During training, 77 subjects (4.9%) acquired MRSA, 26 (3.3%) in the CHG group and 51 (6.5%) in the control group (P = .004). When analyzed for PFT, 24 subjects (3.1%) in the control group but only 6 subjects (0.8%) in the CHG group (P = .001) had USA300. Of the 167 colonizing isolates recovered from 77 subjects, 99 were recovered from the control group, including USA300 (40.4%), USA800 (38.4%), USA1000 (12.1%), and USA100 (6.1%), and 68 were recovered from the CHG group, including USA800 (51.5%), USA100 (23.5%), and USA300 (13.2%). CONCLUSIONS CHG decreased the transmission of MRSA—more specifically, USA300—among military recruits. In addition, USA300 and USA800 outcompeted other MRSA PFTs at incident colonization. Future studies should evaluate the broad-based use of CHG to decrease transmission of USA300 in hospital settings. PMID:22759549
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2012-02-08
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-75,089; TA-W-75,089A] Startek USA, Inc. Alexandria, LA; Startek USA, Inc., Collinsville, VA; Amended Certification Regarding Eligibility... for Worker Adjustment Assistance on January 26, 2011, applicable to workers of StarTek USA, Inc...
The Effect of Added AL2O3 on the Propagation Behavior of an Al/CuO Nanoscale Thermite
2008-01-01
Malchi a, Richard A. Yetter a,*, T. J. Foley b, and Steven F. Son c a The Pennsylvania State University, University Park, PA, USA b Los Alamos National...Laboratory, Los Alamos, NM, USA c Purdue University, West Lafayette, IN, USA U. S. Army Research Office P.O. Box 12211 Research Triangle Park, NC...Pennsylvania State University, University Park, PA, USA b Los Alamos National Laboratory, Los Alamos, NM, USA c Purdue University, West Lafayette, IN, USA
Majdalani, Marianne N; Doumit, Myrna A A; Rahi, Amal C
2014-02-01
Family caregivers have a significant responsibility in the care of their child in the Pediatric Intensive Care Unit (PICU). Parents staying with their child in the PICU have particular needs that should be acknowledged and responded to by clinicians. Several studies have been conducted in the USA and Europe to try to understand the experience of family caregivers of children admitted to the Pediatric Intensive Care Unit. There are no such studies in Lebanon or the Middle East where the culture and support systems differ from other countries. To understand the lived experience of Lebanese parents of children admitted to the PICU in a tertiary hospital in Beirut. Phenomenological study. The study followed purposeful sampling in which 10 parents (mother or father) of children admitted to PICU were interviewed. Data were analyzed following the hermeneutical process as described by Diekelmann and Ironside (1998). A constitutive pattern "Journey into the unknown" which constitutes an overarching theme and four major themes with subthemes emerged from the data. These were: We are human beings with dignity "; "looking for a healthier environment"; Dependence on God and "The need to be in the loop" reveal the parents' journey into the unknown. This qualitative study adds to the knowledge that would help health care workers understand the experience of Lebanese parents with a child in PICU and to highlight the significance of this experience to them. The findings could be used to inform the development of a PICU parental satisfaction instrument for the sample group. Copyright © 2013 Elsevier Ltd. All rights reserved.
Calero-Bernal, Rafael; Cerqueira-Cézar, Camila K; Verma, Shiv Kumar; Mowery, Joseph; Carmena, David; Beckmen, Kimberlee; Dubey, Jitender P
2016-07-01
Sarcocystis sarcocysts are common in muscles of herbivores but are rare in muscles of carnivores. Here, we report sarcocysts in the muscles of a gray wolf (Canis lupus) from Alaska, USA, for the first time. Sarcocysts extracted from the tongue of the wolf were up to 900 μm long and slender and appeared to have a relatively thin wall by light microscope. By transmission electron microscopy, the sarcocyst wall most closely resembled "type 9c," and had a wavy parasitophorous vacuolar membrane folded as pleomorphic villar protrusions (vp), with anastomoses of tips. The vp and the ground substance (gs) layer were smooth without tubules or granules. The gs was up to 2.0 μm thick. The total width of the wall including vp and the gs was 3.5 μm. The vp were up to 1.5 μm long. Mature sarcocysts contained numerous bradyzoites and few metrocytes. The bradyzoites were 9.5 μm long and 1.5 μm wide, and contained all organelles found in Sarcocystis bradyzoites with at least two rhoptries. Molecular characterization showed the highest identity for 18S rRNA, 28S rRNA, ITS-1, and cox1 sequences of Sarcocystis arctica of the Arctic fox (Vulpes lagopus) from Norway. The ultrastructure of S. arctica from the fox is unknown. Here, we provide ultrastructure of S. arctica from the Alaskan wolf for the first time. The definitive host of S. arctica remains unknown.
Peyrani, P; Allen, M; Seligson, D; Roberts, C; Chen, A; Haque, N; Zervos, M; Wiemken, T; Harting, J; Christensen, D; Ramirez, R
2012-03-01
Methicillin-resistant Staphylococcus aureus (MRSA) USA-300 strains have emerged as an important cause of community-acquired infections. These strains have been recognized as an etiology of osteomyelitis but data on their incidence and outcomes are limited. We retrospectively studied the incidence and clinical outcomes of MRSA USA-300 osteomyelitis in patients at the University of Louisville Hospital and the Henry Ford Health System between January 2007 and March 2008. Pulsed-field gel electrophoresis was used to determine USA type. Clinical outcomes were defined as management success versus failure at 12 months. Chi-square tests, Fisher exact tests, and Mann-Whitney tests were used to compare patient characteristics on the basis of clinical outcomes and USA type. Of the 50 patients with MRSA osteomyelitis, 27 (54%) had the USA-300 strain. Clinical failure was identified in 22% (6/27) of the patients with MRSA USA-300 and in 30% (7/23) of the patients with MRSA non-USA-300 osteomyelitis (P = .509). Our results showed that MRSA USA-300 is a significant etiology of MRSA osteomyelitis. With current surgical and medical management, outcomes of patients with MRSA USA-300 osteomyelitis are similar to those of patients with MRSA non-USA-300 osteomyelitis.
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... DEPARTMENT OF ENERGY [FE Docket No. 12-161-LNG] Eni USA Gas Marketing LLC; Application for Blanket..., by Eni USA Gas Marketing LLC (Eni USA Gas Marketing), requesting blanket authorization to export... U.S. law or policy. Eni USA Gas Marketing is requesting this authorization both on its own behalf...
Li, Feiming; Gimpel, John R; Arenson, Ethan; Song, Hao; Bates, Bruce P; Ludwin, Fredric
2014-04-01
Few studies have investigated how well scores from the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) series predict resident outcomes, such as performance on board certification examinations. To determine how well COMLEX-USA predicts performance on the American Osteopathic Board of Emergency Medicine (AOBEM) Part I certification examination. The target study population was first-time examinees who took AOBEM Part I in 2011 and 2012 with matched performances on COMLEX-USA Level 1, Level 2-Cognitive Evaluation (CE), and Level 3. Pearson correlations were computed between AOBEM Part I first-attempt scores and COMLEX-USA performances to measure the association between these examinations. Stepwise linear regression analysis was conducted to predict AOBEM Part I scores by the 3 COMLEX-USA scores. An independent t test was conducted to compare mean COMLEX-USA performances between candidates who passed and who failed AOBEM Part I, and a stepwise logistic regression analysis was used to predict the log-odds of passing AOBEM Part I on the basis of COMLEX-USA scores. Scores from AOBEM Part I had the highest correlation with COMLEX-USA Level 3 scores (.57) and slightly lower correlation with COMLEX-USA Level 2-CE scores (.53). The lowest correlation was between AOBEM Part I and COMLEX-USA Level 1 scores (.47). According to the stepwise regression model, COMLEX-USA Level 1 and Level 2-CE scores, which residency programs often use as selection criteria, together explained 30% of variance in AOBEM Part I scores. Adding Level 3 scores explained 37% of variance. The independent t test indicated that the 397 examinees passing AOBEM Part I performed significantly better than the 54 examinees failing AOBEM Part I in all 3 COMLEX-USA levels (P<.001 for all 3 levels). The logistic regression model showed that COMLEX-USA Level 1 and Level 3 scores predicted the log-odds of passing AOBEM Part I (P=.03 and P<.001, respectively). The present study empirically supported the predictive and discriminant validities of the COMLEX-USA series in relation to the AOBEM Part I certification examination. Although residency programs may use COMLEX-USA Level 1 and Level 2-CE scores as partial criteria in selecting residents, Level 3 scores, though typically not available at the time of application, are actually the most statistically related to performances on AOBEM Part I.
Dan, D T; Gannavarapu, B; Lee, J G; Chang, K; Muthusamy, V R
2014-08-01
With the recent availability of removable esophageal stents, endoscopic stenting has been utilized to treat refractory benign esophageal strictures (RBES). The objective of this study was to review the feasibility and effectiveness of removable esophageal stents to treat RBES. Patients who received removable esophageal stents for the treatment of RBES at the institution between 2004-2010 using its stent implantation logs and endoscopic database were retrospectively identified. Patient demographics, stricture etiology and location, stent and procedure characteristics, and clinical outcomes were obtained. Twenty-five patients with a mean age of 70 (72% male) underwent initial stent placement; 24 were successful. Overall clinical success was achieved in five of the 19 patients (26%) ultimately undergoing stent removal. RBES etiologies included anastomotic (13), radiation (5), peptic (3), chemotherapy (1), scleroderma (1), and unknown (2). Alimaxx-E (Merit-Endotek, South Jordan, UT, USA) stents were placed in 20 patients and Polyflex (Boston Scientific, Natick, MA, USA) stents were used in five patients. Immediate complications included failed deployment (1) and chest pain (7). Five patients died prior to stent removal. Stent migration was found in 53% (10/19) of patients who underwent stent removal: nine required additional therapy and one had symptom resolution. Out of the nine patients without stent migration, five required additional therapy and four had symptom resolution. Although placement of removable esophageal stents for RBES is technically feasible, it is frequently complicated by stent migration and chest pain. In addition, few patients achieved long-term stricture resolution after initial stenting. In this study, most patients ultimately required repeated stenting and/or dilations to maintain relief of dysphagia. © 2012 Copyright the Authors. Journal compilation © 2012, Wiley Periodicals, Inc. and the International Society for Diseases of the Esophagus.
Kepka, Deanna; Ding, Qian; Bodson, Julia; Warner, Echo L; Mooney, Kathi
2015-12-01
Latinos suffer a disproportionate burden of human papillomavirus (HPV)-preventable cancers, yet uptake and completion of the HPV vaccine among Latinos is below recommendations. Reasons for low HPV vaccine uptake among Latinos in Utah are unknown. We surveyed Latino parents of HPV vaccine age-eligible adolescents (N=118). Univariable analyses identified sociodemographic characteristics associated with HPV vaccine awareness, interest, and uptake for daughter(s) and/or son(s) using chi-square tests or Fisher's exact tests. More parents who had lived in the USA for 15 years or more had vaccinated their daughter (43.6 vs. 32.5%, p=0.035) compared to those living in the USA for shorter time periods. Parents born in Mexico reported their son had not received the HPV vaccine (74.6 vs. 58.3%, p=0.049) more than those born elsewhere. Parents with Mexican birthplace and ancestry reported not knowing about the HPV vaccine as the main barrier to vaccinating daughters (47.1 vs. 5.9%, p=0.002 for both) and sons (birthplace 38.3 vs. 10.3%, p=0.007; ancestry 37.1 vs. 11.1%, p=0.013) compared to those born or descending elsewhere. Non-acculturated parents with a son were more likely to report not knowing about the HPV vaccine as the main barrier to vaccine receipt (47.6 vs. 12.5%, p<0.001). Our results focus on Latinos in an understudied region and complement prior research in other regions. This study may have implications for designing culturally tailored interventions to improve uptake of the HPV vaccine among the growing population of Latinos in Utah, and other states in the Intermountain West.
Joyner, Priscilla H; Kelly, Sean; Shreve, Allison A; Snead, Sarah E; Sleeman, Jonathan M; Pettit, Denise A
2006-04-01
Sixty-one birds of prey admitted to The Wildlife Center of Virginia (WCV; Waynesboro, Virginia, USA) from June to November 2003 were tested for West Nile virus (WNV) infection. Choanal and/or cloacal swabs were obtained and submitted to Virginia's Division of Consolidated Laboratory Services (Richmond, Virginia, USA) for analysis with real-time reverse transcriptase polymerase chain reaction (RT-PCR). Forty birds of prey were positive for WNV by RT-PCR. Five avian families and nine species of raptors were represented, with great horned owls (Bubo virginianus) and red-tailed hawks (Buteo jamaicensis) most frequently affected. Presenting clinical signs were consistent with previous reports of WNV infection in raptors; however, these differed between species. Of WNV positive birds, nonspecific signs of illness were the most common clinical findings, particularly in red-tailed hawks; signs included dehydration (n = 20), emaciation (n = 18), and depression (n = 15). Neurologic abnormalities were frequently identified, especially in great horned owls, and included head tremors (n = 17), ataxia (n = 13), head incoordination (n = 7), torticollis (n = 3), nystagmus (n = 3), and head tilt (n = 3). Great horned owls exhibited anemia and leukocytosis with heterophilia, eosinophilia, and monocytosis consistent with chronic inflammation. Red-tailed hawks were anemic with a heterophilic leukocytosis and regenerative left shift. The majority of WNV cases occurred during August and September; there was a marked increase in the number of raptors admitted to WCV during these months followed by a marked decrease during October, November, and December. This pattern differed from mean monthly admissions during the previous 10 years and suggests a negative impact on local raptor populations. The effects of WNV on avian populations are largely unknown; however, because of their ecological importance, further investigation of the effects of WNV on raptor populations is warranted.
Speeding up tsunami wave propagation modeling
NASA Astrophysics Data System (ADS)
Lavrentyev, Mikhail; Romanenko, Alexey
2014-05-01
Trans-oceanic wave propagation is one of the most time/CPU consuming parts of the tsunami modeling process. The so-called Method Of Splitting Tsunami (MOST) software package, developed at PMEL NOAA USA (Pacific Marine Environmental Laboratory of the National Oceanic and Atmospheric Administration, USA), is widely used to evaluate the tsunami parameters. However, it takes time to simulate trans-ocean wave propagation, that is up to 5 hours CPU time to "drive" the wave from Chili (epicenter) to the coast of Japan (even using a rather coarse computational mesh). Accurate wave height prediction requires fine meshes which leads to dramatic increase in time for simulation. Computation time is among the critical parameter as it takes only about 20 minutes for tsunami wave to approach the coast of Japan after earthquake at Japan trench or Sagami trench (as it was after the Great East Japan Earthquake on March 11, 2011). MOST solves numerically the hyperbolic system for three unknown functions, namely velocity vector and wave height (shallow water approximation). The system could be split into two independent systems by orthogonal directions (splitting method). Each system can be treated independently. This calculation scheme is well suited for SIMD architecture and GPUs as well. We performed adaptation of MOST package to GPU. Several numerical tests showed 40x performance gain for NVIDIA Tesla C2050 GPU vs. single core of Intel i7 processor. Results of numerical experiments were compared with other available simulation data. Calculation results, obtained at GPU, differ from the reference ones by 10^-3 cm of the wave height simulating 24 hours wave propagation. This allows us to speak about possibility to develop real-time system for evaluating tsunami danger.
Howell, P.J.; Dunham, J.B.; Sankovich, P.M.
2010-01-01
Understanding thermal habitat use by migratory fish has been limited by difficulties in matching fish locations with water temperatures. To describe spatial and temporal patterns of thermal habitat use by migratory adult bull trout, Salvelinus confluentus, that spawn in the Lostine River, Oregon, we employed a combination of archival temperature tags, radio tags, and thermographs. We also compared temperatures of the tagged fish to ambient water temperatures to determine if the fish were using thermal refuges. The timing and temperatures at which fish moved upstream from overwintering areas to spawning locations varied considerably among individuals. The annual maximum 7-day average daily maximum (7DADM) temperatures of tagged fish were 16-18 ??C and potentially as high as 21 ??C. Maximum 7DADM ambient water temperatures within the range of tagged fish during summer were 18-25 ??C. However, there was no evidence of the tagged fish using localized cold water refuges. Tagged fish appeared to spawn at 7DADM temperatures of 7-14 ??C. Maximum 7DADM temperatures of tagged fish and ambient temperatures at the onset of the spawning period in late August were 11-18 ??C. Water temperatures in most of the upper Lostine River used for spawning and rearing appear to be largely natural since there has been little development, whereas downstream reaches used by migratory bull trout are heavily diverted for irrigation. Although the population effects of these temperatures are unknown, summer temperatures and the higher temperatures observed for spawning fish appear to be at or above the upper range of suitability reported for the species. Published 2009. This article is a US Governmentwork and is in the public domain in the USA.
Asher, W.E.; Luo, W.; Campo, K.W.; Bender, D.A.; Robinson, K.W.; Zogorski, J.S.; Pankow, J.F.
2007-01-01
Position-dependent concentrations of trichloroethylene and methyl-tert-butyl ether are considered for a 2.81-km section of the Aberjona River in Massachusetts, USA. This river flows through Woburn and Winchester (Massachusetts, USA), an area that is highly urbanized, has a long history of industrial activities dating to the early 1800s, and has gained national attention because of contamination from chlorinated solvent compounds in Woburn wells G and H. The river study section is in Winchester and begins approximately five stream kilometers downstream from the Woburn wells superfund site. Approximately 300 toxic release sites are documented in the watershed upstream from the terminus of the study section. The inflow to the river study section is considered one source of contamination. Other sources are the atmosphere, a tributary flow, and groundwater flows entering the river; the latter are categorized according to stream zone (1, 2, 3, etc.). Loss processes considered include outflows to groundwater and water-to-atmosphere transfer of volatile compounds. For both trichloroethylene and methyl-rerf-butyl ether, degradation is neglected over the timescale of interest. Source apportionment fractions with assigned values ??inflow, ??1, ??2, ??3, etc. are tracked by a source apportionment model. The strengths of the groundwater and tributary sources serve as fitting parameters when minimizing a reduced least squares statistic between water concentrations measured during a synoptic study in July 2001 versus predictions from the model. The model fits provide strong evidence of substantial unknown groundwater sources of trichloroethylene and methyl-tert-butyl ether amounting to tens of grams per day of trichloroethylene and methyl-tert-butyl ether in the river along the study section. Modeling in a source apportionment manner can be useful to water quality managers allocating limited resources for remediation and source control. ?? 2007 SETAC.
Subcutaneous ICD screening with the Boston Scientific ZOOM programmer versus a 12-lead ECG machine.
Chang, Shu C; Patton, Kristen K; Robinson, Melissa R; Poole, Jeanne E; Prutkin, Jordan M
2018-02-24
The subcutaneous implantable cardioverter-defibrillator (S-ICD) requires preimplant screening to ensure appropriate sensing and reduce risk of inappropriate shocks. Screening can be performed using either an ICD programmer or a 12-lead electrocardiogram (ECG) machine. It is unclear whether differences in signal filtering and digital sampling change the screening success rate. Subjects were recruited if they had a transvenous single-lead ICD without pacing requirements or were candidates for a new ICD. Screening was performed using both a Boston Scientific ZOOM programmer (Marlborough, MA, USA) and General Electric MAC 5000 ECG machine (Fairfield, CT, USA). A pass was defined as having at least one lead that fit within the screening template in both supine and sitting positions. A total of 69 subjects were included and 27 sets of ECG leads had differing screening results between the two machines (7%). Of these sets, 22 (81%) passed using the ECG machine but failed using the programmer and five (19%) passed using the ECG machine but failed using the programmer (P < 0.001). Four subjects (6%) passed screening using the ECG machine but failed using the programmer. No subject passed screening with the programmer but failed with the ECG machine. There can be occasional disagreement in S-ICD patient screening between an ICD programmer and ECG machine, all of whom passed with the ECG machine but failed using the programmer. On a per lead basis, the ECG machine passes more subjects. It is unknown what the inappropriate shock rate would be if an S-ICD was implanted. Clinical judgment should be used in borderline cases. © 2018 Wiley Periodicals, Inc.
Saari, Ryan J; Cooper, David K C
2017-07-01
When clinical xenotransplantation is introduced, the costs associated with acquisition of a genetically engineered pig organ are as yet unknown. How will these costs compare with those currently associated with the acquisition of deceased human organs? An understanding of the financial aspects of deceased organ and tissue procurement in the USA is therefore worthwhile. We have therefore attempted to review certain economic aspects of non-profit and for-profit organizations that provide cadaveric organs and/or tissues for purposes of transplantation into patients with end-stage organ failure, cellular deficiencies, or in need of reconstructive procedures. We briefly consider the laws, organizations, and business practices that govern the acquisition, processing, and/or distribution of cadaveric organs and tissues, and the economic implications of industry practices. In particular, we explore and highlight what we perceive as a lack of transparency and oversight with regard to financial practices, and we question whether donor families would be entirely happy with the business environment that has developed from their altruistic donations. Until xenotransplantation becomes established clinically, which will negate the need for any system of organ procurement and allocation, we suggest that those involved in organ and cell transplantation, as well as those who participate in reconstructive surgery, should take responsibility to ensure that the financial practices associated with procurement are transparent, and overseen/regulated by a responsible authority. We suggest the major transplant societies should take a lead in this respect. The ability to acquire a genetically engineered pig organ whenever required through a simple commercial transaction (as in the acquisition of a life-saving drug) will be greatly to the patient's benefit. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Cassani, John R.; Croshaw, Dean A.; Bozzo, Joseph; Brooks, Brenda; Everham, Edwin M.; Ceilley, David W.; Hanson, Deborah
2015-01-01
Herpetofaunal declines have been documented globally, and southern Florida, USA, is an especially vulnerable region because of high impacts from hydrological perturbations and nonindigenous species. To assess the extent of recent change in herpetofauna community composition, we established a baseline inventory during 1995-97 at a managed preserve in a habitat rich area of southwest Florida, and repeated our sampling methods fifteen years later (2010-11). Nine drift fence arrays were placed in four habitat types: mesic flatwood, mesic hammock, depression marsh, and wet prairie. Trapping occurred daily for one week during 7-8 sampling runs in each period (57 and 49 total sampling days, respectively). Species richness was maintained in mesic hammock habitats but varied in the others. Catch rates of several native species (Anaxyrus terrestris, Lithobates grylio, Anolis carolinensis, Nerodia fasciata) declined significantly. Other native species (Lithobates sphenocephalus, Siren lacertian, and Notophthalmus viridescens piaropicola) that were abundant in 1995-97 declined by greater than 50%. Catch rate of only two species (the nonindigenous Anolis sagrei and the native Diadophis punctatus) increased significantly. Hierarchical cluster analysis indicated similarity within habitat types but significant dissimilarity between sampling periods, confirming shifts in community composition. Analysis of individual species’ contributions to overall similarity across habitats shows a shift from dominance of native species in the 1990s to increased importance of nonindigenous species in 2010-11. Although natural population fluctuations may have influenced differences between the two sampling periods, our results suggest considerable recent change in the structure and composition of this southwest Florida herpetofaunal community. The causes are unknown, but hydrological shifts and ecological impacts of nonindigenous species may have contributed. PMID:26016475
Osburn, Magdalena R.; LaRowe, Douglas E.; Momper, Lily M.; Amend, Jan P.
2014-01-01
The deep subsurface is an enormous repository of microbial life. However, the metabolic capabilities of these microorganisms and the degree to which they are dependent on surface processes are largely unknown. Due to the logistical difficulty of sampling and inherent heterogeneity, the microbial populations of the terrestrial subsurface are poorly characterized. In an effort to better understand the biogeochemistry of deep terrestrial habitats, we evaluate the energetic yield of chemolithotrophic metabolisms and microbial diversity in the Sanford Underground Research Facility (SURF) in the former Homestake Gold Mine, SD, USA. Geochemical data, energetic modeling, and DNA sequencing were combined with principle component analysis to describe this deep (down to 8100 ft below surface), terrestrial environment. SURF provides access into an iron-rich Paleoproterozoic metasedimentary deposit that contains deeply circulating groundwater. Geochemical analyses of subsurface fluids reveal enormous geochemical diversity ranging widely in salinity, oxidation state (ORP 330 to −328 mV), and concentrations of redox sensitive species (e.g., Fe2+ from near 0 to 6.2 mg/L and Σ S2- from 7 to 2778μg/L). As a direct result of this compositional buffet, Gibbs energy calculations reveal an abundance of energy for microorganisms from the oxidation of sulfur, iron, nitrogen, methane, and manganese. Pyrotag DNA sequencing reveals diverse communities of chemolithoautotrophs, thermophiles, aerobic and anaerobic heterotrophs, and numerous uncultivated clades. Extrapolated across the mine footprint, these data suggest a complex spatial mosaic of subsurface primary productivity that is in good agreement with predicted energy yields. Notably, we report Gibbs energy normalized both per mole of reaction and per kg fluid (energy density) and find the later to be more consistent with observed physiologies and environmental conditions. Further application of this approach will significantly expand our understanding of the deep terrestrial biosphere. PMID:25429287
Spatial and Temporal Comparison of DNRA Communities in New River Estuary, USA
NASA Astrophysics Data System (ADS)
Song, B.; Lisa, J.; Tobias, C. R.
2016-02-01
Dissimilatory nitrate reduction to ammonium (DNRA) is an important nitrate respiring pathway, competing with denitrification, in various ecosystems. Studies examining the diversity and composition of DNRA communities are limited and their link to DNRA activity is unknown. We conducted a multidisciplinary investigation of sediment communities in the upper reaches of a eutrophic estuary to examine spatial and temporal variation of DNRA community structures and determine their linkage to activities. Sediment samples were collected seasonally from two study sites (AA2 and JAX) in the New River Estuary, North Carolina, USA. 15N-nitrate tracer experiments were conducted to measure potential DNRA rates while abundance of DNRA communities was measured using quantitative PCR of cytochrome C nitrite reductase genes (nrfA). Composition and diversity of DNRA communities were also examined based on next generation sequencing (NGS) of nrfA genes using an Ion Torrent PGM. Bioinformatic analysis was conducted using the FunGene pipeline and Mothur program. Higher DNRA activities were measured at JAX and associated with higher abundance of nrfA genes. Seasonal variation in DNRA rates and nrfA gene abundance was more evident at JAX than AA2. Nitrate concentration and dissolved oxygen in bottom water were significantly and positively correlated with activities and abundance of DNRA communities. The nrfA NGS analysis revealed that spatial variation of DNRA communities was much greater than temporal variation with salinity, dissolved organic carbon, and nitrate as the most important environmental variables affecting these communities. Diversity of DNRA communities was negative correlated with the DNRA rates and nrfA gene abundance, which suggests that dominant members of the DNRA community are responsible for higher rates. Thus, our multidisciplinary study clearly demonstrates the linkage between structure and activities of DNRA communities in the upper reaches of New River Estuary.
Kocher, Jacob F; Lindesmith, Lisa C; Debbink, Kari; Beall, Anne; Mallory, Michael L; Yount, Boyd L; Graham, Rachel L; Huynh, Jeremy; Gates, J Edward; Donaldson, Eric F; Baric, Ralph S
2018-05-22
Emerging zoonotic viral diseases remain a challenge to global public health. Recent surveillance studies have implicated bats as potential reservoirs for a number of viral pathogens, including coronaviruses and Ebola viruses. Caliciviridae represent a major viral family contributing to emerging diseases in both human and animal populations and have been recently identified in bats. In this study, we blended metagenomics, phylogenetics, homology modeling, and in vitro assays to characterize two novel bat calicivirus (BtCalV) capsid sequences, corresponding to strain BtCalV/A10/USA/2009, identified in Perimyotis subflavus near Little Orleans, MD, and bat norovirus. We observed that bat norovirus formed virus-like particles and had epitopes and receptor-binding patterns similar to those of human noroviruses. To determine whether these observations stretch across multiple bat caliciviruses, we characterized a novel bat calicivirus, BtCalV/A10/USA/2009. Phylogenetic analysis revealed that BtCalV/A10/USA/2009 likely represents a novel Caliciviridae genus and is most closely related to "recoviruses." Homology modeling revealed that the capsid sequences of BtCalV/A10/USA/2009 and bat norovirus resembled human norovirus capsid sequences and retained host ligand binding within the receptor-binding domains similar to that seen with human noroviruses. Both caliciviruses bound histo-blood group antigens in patterns that overlapped those seen with human and animal noroviruses. Taken together, our results indicate the potential for bat caliciviruses to bind histo-blood group antigens and overcome a significant barrier to cross-species transmission. Additionally, we have shown that bat norovirus maintains antigenic epitopes similar to those seen with human noroviruses, providing further evidence of evolutionary descent. Our results reiterate the importance of surveillance of wild-animal populations, especially of bats, for novel viral pathogens. IMPORTANCE Caliciviruses are rapidly evolving viruses that cause pandemic outbreaks associated with significant morbidity and mortality globally. The animal reservoirs for human caliciviruses are unknown; bats represent critical reservoir species for several emerging and zoonotic diseases. Recent reports have identified several bat caliciviruses but have not characterized biological functions associated with disease risk, including their potential emergence in other mammalian populations. In this report, we identified a novel bat calicivirus that is most closely related to nonhuman primate caliciviruses. Using this new bat calicivirus and a second norovirus-like bat calicivirus capsid gene sequence, we generated virus-like particles that have host carbohydrate ligand binding patterns similar to those of human and animal noroviruses and that share antigens with human noroviruses. The similarities to human noroviruses with respect to binding patterns and antigenic epitopes illustrate the potential for bat caliciviruses to emerge in other species and the importance of pathogen surveillance in wild-animal populations. Copyright © 2018 Kocher et al.
2004-03-05
KENNEDY SPACE CENTER, FLA. - The STS-114 crew pose for a photo in front of a solid rocket booster aft skirt in the SRB Assembly and Refurbishment Facility. In front, from left, are Cynthia Perrons, electrical technician with United Space Alliance; Commander Eileen Collins, Pilot James Kelly, and Mission Specialists Charles Camarda and Andrew Thomas. In back are Paul Gutierrez, associate program manager in SRB Element, USA; John Cleary Jr., electrical engineer with USA; Mike Leppert, project lead, Manufacturing Operations, USA; Don Noah, Materials and Processes engineer, USA; Bob Herman, deputy associate program manager, SRB Element, USA; Mission Specialist Soichi Noguchi; Dale Marlow, thermal protection system engineer with USA; Mission Specialist Stephen Robinson; Greg Henry, director, Manufacturing Operations, USA.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-08
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,850; TA-W-74,850A] StarTek USA, Inc., 244 Dundee Avenue, Greeley, CO; StarTek USA, Inc., 1250 H Street, Greeley, CO; Amended... workers and former workers of StarTek USA, Inc., Greeley, Colorado. The Department's notice of...
Lao, Li-Feng; Daubs, Michael David; Phan, Kevin H; Wang, Jeffrey C
2013-11-01
To compare orthopedics publications from USA, Japan and China. Scientific papers belong to ''Orthopedics'' category of Science Citation Index Expanded subject categories were retrieved from the "PubMed'' and ''Web of Knowledge'' online databases. In the field of orthopedics, the annual number increased significantly from 2000 to 2012 in the three countries (p<0.001). The share of articles increased significantly in China, but decreased significantly in Japan and USA (p<0.05). In 2012, USA contributed 35.3% of the total world output in orthopedics field and ranked 1st; Japan contributed 5.9% and ranked 4th; China contributed 5.2% and ranked 5th. Publications from USA had the highest accumulated IFs and the highest total citations of articles (USA > Japan > China, p<0.001). Average IF from USA was much higher than Japan and China (p<0.001). USA published the most articles in the top ten orthopedics journals (USA (14355) > Japan (1702) > China (487), p<0.01). Although China has undergone significant increase in annual number and percentage of scientific publication in orthopedics journals, it still lags far behind USA and Japan in the field of orthopedics in terms of quantity and quality.
Tattevin, Pierre; Schwartz, Brian S; Graber, Christopher J; Volinski, Joann; Bhukhen, Akta; Bhukhen, Arti; Mai, Thuy T; Vo, Nhung H; Dang, Denise N; Phan, Tiffany HaiVan; Basuino, Li; Perdreau-Remington, Françoise; Chambers, Henry F; Diep, Binh An
2012-09-01
Since its emergence in 2000, epidemic spread of the methicillin-resistant Staphylococcus aureus (MRSA) clone USA300 has led to a high burden of skin and soft tissue infections (SSTIs) in the United States, yet its impact on MRSA bloodstream infections (BSIs) is poorly characterized. To assess clonality of the MRSA isolates causing SSTI and BSI during the epidemic period, a stratified, random sample of 1350 unique infection isolates (from a total of 7252) recovered at the Community Health Network of San Francisco from 2000 to 2008 were selected for genotyping. Risk factors and outcomes for 549 BSI cases caused by the USA300 epidemic clone and non-USA300 MRSA clones were assessed by retrospective review of patient medical records. From 2000 to 2008, secular trends of USA300 SSTI and USA300 BSI were strongly correlated (Pearson r = 0.953). USA300 accounted for 55% (304/549) of BSIs as it was the predominant MRSA clone that caused community-associated (115/160), healthcare-associated community-onset (125/207), and hospital-onset (64/182) BSIs. Length of hospitalization after BSI diagnosis and mortality rates for USA300 and non-USA300 were similar. Two independent risk factors for USA300 BSI were identified: concurrent SSTI (adjusted relative risk, 1.4 [95% confidence interval {CI}, 1.2-1.6]) and anti-MRSA antimicrobial use in the preceding 30 days (0.7 [95% CI, .6-.8]). Isolates from concurrent SSTI were indistinguishable genotypically from the USA300 isolates that caused BSI. USA300 SSTIs serve as a source for BSI. Strategies to control the USA300 SSTI epidemic may lessen the severity of the concurrent USA300 BSI epidemic.
1969-07-25
The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named “Eagle’’, carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. This photograph was taken as the mission’s first loaded sample return container arrived at Ellington Air Force Base by air from the Pacific recovery area. The rock box was immediately taken to the Lunar Receiving Laboratory at the Manned Spacecraft Center (MSC) in Houston, Texas. Happily posing for the photograph with the rock container are (L-R) Richard S. Johnston (back), special assistant to the MSC Director; George M. Low, MSC Apollo Spacecraft Program manager; George S. Trimble (back), MSC Deputy Director; Lt. General Samuel C. Phillips, Apollo Program Director, Office of Manned Spaceflight at NASA headquarters; Eugene G. Edmonds, MSC Photographic Technology Laboratory; Dr. Thomas O. Paine, NASA Administrator; and Dr. Robert R. Gilruth, MSC Director.
Ionospheric modifications detected by a dense network of single frequency GNSS receivers
NASA Astrophysics Data System (ADS)
Mrak, S.; Semeter, J. L.
2017-12-01
It has been predicted that the region of totality during a total solar eclipse can launch atmospheric gravity waves with large enough amplitude to cause traveling ionospheric disturbances (TIDs). We report initial results from a remote sensing campaign involving a dense hybrid network of single- and dual-frequency GNSS receivers deployed underneath the 21 August 2017 solar eclipse. The campaign took place in central Missouri, involving 84 Trimble dual-frequency receivers, complemented by 2 additional 50 Hz dual-frequency receivers and 15 single-frequency receivers, together constructing 100 receivers with average mutual separation of less than 25 km and with a time resolution of 1 second or better. The initial results show a crescent shaped enhancement bulge in front of region of totality, extending all the way from Canada to Gulf of Mexico. In addition, in the path of totality is noticed a great depletion region, followed by a pair of transverse waves propagating in west-east direction. In the following months, we will explore the transition region carried by the totality by a virtue of hyper dense network of GNSS receivers with 1 second resolution. In addition to TEC data decomposition we will explore effects of the totality on the raw measurements (phase, code and signal intensity), and to the navigation solution which is likely to be effected by a different propagation conditions with respect to other days.
Investigation of a L1-optimized choke ring ground plane for a low-cost GPS receiver-system
NASA Astrophysics Data System (ADS)
Zhang, Li; Schwieger, Volker
2018-01-01
Besides the geodetic dual-frequency GNSS receivers-systems (receiver and antenna), there are also low-cost single-frequency GPS receiver-systems. The multipath effect is a limiting factor of accuracy for both geodetic dual-frequency and low-cost single-frequency GPS receivers. And the multipath effect is for the short baselines dominating error (typical for the monitoring in Engineering Geodesy). So accuracy and reliability of GPS measurement for monitoring can be improved by reducing the multipath signal. In this paper, the self-constructed L1-optimized choke ring ground plane (CR-GP) is applied to reduce the multipath signal. Its design will be described and its performance will be investigated. The results show that the introduced low-cost single-frequency GPS receiver-system, which contains the Ublox LEA-6T single-frequency GPS receiver and Trimble Bullet III antenna with a self-constructed L1-optimized CR-GP, can reach standard deviations of 3 mm in east, 5 mm in north and 9 mm in height in the test field which has many reflectors. This accuracy is comparable with the geodetic dual-frequency GNSS receiver-system. The improvement of the standard deviation of the measurement using the CR-GP is about 50 % and 35 % compared to the used antenna without shielding and with flat ground plane respectively.
First Apollo 11 Lunar Samples Arrive at the Manned Spacecraft Center (MSC)
NASA Technical Reports Server (NTRS)
1969-01-01
The Apollo 11 mission, the first manned lunar mission, launched from the Kennedy Space Center, Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Aboard the space craft were astronauts Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin Jr., Lunar Module (LM) pilot. The CM, piloted by Michael Collins remained in a parking orbit around the Moon while the LM, named 'Eagle'', carrying astronauts Neil Armstrong and Edwin Aldrin, landed on the Moon. During 2½ hours of surface exploration, the crew collected 47 pounds of lunar surface material for analysis back on Earth. This photograph was taken as the mission's first loaded sample return container arrived at Ellington Air Force Base by air from the Pacific recovery area. The rock box was immediately taken to the Lunar Receiving Laboratory at the Manned Spacecraft Center (MSC) in Houston, Texas. Happily posing for the photograph with the rock container are (L-R) Richard S. Johnston (back), special assistant to the MSC Director; George M. Low, MSC Apollo Spacecraft Program manager; George S. Trimble (back), MSC Deputy Director; Lt. General Samuel C. Phillips, Apollo Program Director, Office of Manned Spaceflight at NASA headquarters; Eugene G. Edmonds, MSC Photographic Technology Laboratory; Dr. Thomas O. Paine, NASA Administrator; and Dr. Robert R. Gilruth, MSC Director.
Improving the Quality of Low-Cost GPS Receiver Data for Monitoring Using Spatial Correlations
NASA Astrophysics Data System (ADS)
Zhang, Li; Schwieger, Volker
2016-06-01
The investigations on low-cost single frequency GPS receivers at the Institute of Engineering Geodesy (IIGS) show that u-blox LEA-6T GPS receivers combined with Trimble Bullet III GPS antennas containing self-constructed L1-optimized choke rings can already obtain an accuracy in the range of millimeters which meets the requirements of geodetic precise monitoring applications (see [
Theoretical and Applied Research in the Field of Higher Geodesy Conducted in Rzeszow
NASA Astrophysics Data System (ADS)
Kadaj, Roman; Świętoń, Tomasz
2016-06-01
Important qualitative changes were taking place in polish geodesy in last few years. It was related to application of new techniques and technologies and to introduction of European reference frames in Poland. New reference stations network ASG-EUPOS, together with Internet services which helps in precise positioning was created. It allows to fast setting up precise hybrid networks. New, accurate satellite networks became the basis of new definitions in the field of reference systems. Simultaneously arise the need of new software, which enables to execute the geodetic works in new technical conditions. Authors had an opportunity to participate in mentioned undertakings, also under the aegis of GUGiK, by creation of methods, algorithms and necessary software tools. In this way the automatic postprocessing module (APPS) in POZGEO service, a part of ASG-EUPOS system came into being. It is an entirely polish product which works in Trimble environment. Universal software for transformation between PLETRF89, PL-ETRF2000, PULKOWO'42 reference systems as well as defined coordinate systems was created (TRANSPOL v. 2.06) and published as open product. An essential functional element of the program is the quasi-geoid model PL-geoid-2011, which has been elaborated by adjustment (calibration) of the global quasi-geoid model EGM2008 to 570 geodetic points (satellite-leveling points). Those and other studies are briefly described in this paper.
78 FR 49270 - Information Collection; MyUSA
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-13
... Floor, Washington, DC 20405- 0001. ATTN: Hada Flowers/IC 3090-00XX; MyUSA. Instructions: Please submit...-4755. ATTN: Hada Flowers/ IC 3090-00xx; MyUSA. Please cite OMB Control No. 3090-XXXX; MyUSA, in all...
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2012-08-09
... DEPARTMENT OF LABOR Employment and Training Administration TA-W-81,520, T-Mobile USA, Inc., Call Center, Allentown, PA; TA- W-81,520G, T-Mobile USA, Inc., Headquarters Office, Bellevue, WA; Amended... of T-Mobile USA, Inc., Call Center, Allentown, Pennsylvania (TA-W-81,520), Fort Lauderdale, Florida...
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2013-12-18
... current ownership of Quick, and its wholly owned subsidiary Quick Coach Lines USA Inc. (Quick USA... passengers (MC-205116). Quick USA is a wholly owned subsidiary of Quick. When Royal acquires control of Quick, it will also obtain control of Quick USA. Quick USA is currently inactive and does not provide any...
MRSA USA300 at Alaska Native Medical Center, Anchorage, Alaska, USA, 2000–2006
Rudolph, Karen M.; Hennessy, Thomas W.; Zychowski, Diana L.; Asthi, Karthik; Boyle-Vavra, Susan; Daum, Robert S.
2012-01-01
To determine whether methicillin-resistant Staphylococcus aureus (MRSA) USA300 commonly caused infections among Alaska Natives, we examined clinical MRSA isolates from the Alaska Native Medical Center, Anchorage, during 2000–2006. Among Anchorage-region residents, USA300 was a minor constituent among MRSA isolates in 2000–2003 (11/68, 16%); by 2006, USA300 was the exclusive genotype identified (10/10). PMID:22264651
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2010-02-09
.../k/a IFS S.A, its Agents, Affiliated, Related and Partner Companies, and International First Service Argentina a/k/a AR-IFS, its Agents, Affiliated, Related and Partner Companies, and International First Service USA, Inc. a/k/a IFS USA, Inc. d/b/a Global Wine Logistics USA Inc. a/k/a GWL USA, Inc., and Global...
Mark-resight abundance estimation under incomplete identification of marked individuals
McClintock, Brett T.; Hill, Jason M.; Fritz, Lowell; Chumbley, Kathryn; Luxa, Katie; Diefenbach, Duane R.
2014-01-01
Often less expensive and less invasive than conventional mark–recapture, so-called 'mark-resight' methods are popular in the estimation of population abundance. These methods are most often applied when a subset of the population of interest is marked (naturally or artificially), and non-invasive sighting data can be simultaneously collected for both marked and unmarked individuals. However, it can often be difficult to identify marked individuals with certainty during resighting surveys, and incomplete identification of marked individuals is potentially a major source of bias in mark-resight abundance estimators. Previously proposed solutions are ad hoc and will tend to underperform unless marked individual identification rates are relatively high (>90%) or individual sighting heterogeneity is negligible.Based on a complete data likelihood, we present an approach that properly accounts for uncertainty in marked individual detection histories when incomplete identifications occur. The models allow for individual heterogeneity in detection, sampling with (e.g. Poisson) or without (e.g. Bernoulli) replacement, and an unknown number of marked individuals. Using a custom Markov chain Monte Carlo algorithm to facilitate Bayesian inference, we demonstrate these models using two example data sets and investigate their properties via simulation experiments.We estimate abundance for grassland sparrow populations in Pennsylvania, USA when sampling was conducted with replacement and the number of marked individuals was either known or unknown. To increase marked individual identification probabilities, extensive territory mapping was used to assign incomplete identifications to individuals based on location. Despite marked individual identification probabilities as low as 67% in the absence of this territorial mapping procedure, we generally found little return (or need) for this time-consuming investment when using our proposed approach. We also estimate rookery abundance from Alaskan Steller sea lion counts when sampling was conducted without replacement, the number of marked individuals was unknown, and individual heterogeneity was suspected as non-negligible.In terms of estimator performance, our simulation experiments and examples demonstrated advantages of our proposed approach over previous methods, particularly when marked individual identification probabilities are low and individual heterogeneity levels are high. Our methodology can also reduce field effort requirements for marked individual identification, thus, allowing potential investment into additional marking events or resighting surveys.
Eri, Tine S; Bondas, Terese; Gross, Mechthild M; Janssen, Patricia; Green, Josephine M
2015-03-01
to integrate findings of individual studies in order to broaden the understanding of first-time mothers' experiences of early labour. the methodology was metasynthesis which is based on the interpretive meta-ethnography described by Noblit and Hare (1988). Metasynthesis is research on research which synthesises the findings of previous qualitative studies, and the focus is on interpretation and the creation of new knowledge. all included studies originated from high resource countries (USA 2, UK 4, and Scandinavia 5) and all were carried out in a context of hospital based maternity care. a total of 231 women participated in the studies. 11 articles were included. The main results are presented with the metaphor a balancing act in an unknown territory. The 'unknown territory' has a double meaning: as the personal experience of going into labour for the first time and as encountering the maternity care system. On both levels women have to make significant decisions: whether labour really has started and subsequently when to go to the hospital. A key challenge is to balance the arrival on the labour ward at the 'right' time, not too early and not too late. Arriving at the 'right' time leads to a positive path, while arriving 'too soon' might lead to a cascade of negative experiences. The results are further presented with five central themes: 'Finding out if labour has started is absorbing'; 'Dealing with labour at home'; 'Trying to arrive at the labour ward at the right time'; 'There is always a risk of being sent home'; 'Encountering health professionals arouses strong emotions'. the metasynthesis broadens the understanding of first-time mothers' experiences of early labour, and suggests that women's needs when planning a hospital birth are not being adequately met at this stage in the labour process. Three areas of future research are suggested: how to support and strengthen women during pregnancy in order to cope with early labour; women's experiences of early labour when planning a birth in contexts other than hospital; and to continue to investigate new ways of giving care during early labour. Copyright © 2014 Elsevier Ltd. All rights reserved.
Formation and Decay of the Inner Electron Radiation Belt
2017-01-09
Colorado Boulder, Boulder, Colorado, USA, 4NASA/Goddard Space Flight Center, Greenbelt, Maryland, USA, 5Department of Physics and Astronomy , Dartmouth...Colorado Boulder, Boulder, Colorado, USA, 4NASA Goddard Space Flight Center, Greenbelt, Maryland, USA, 5Department of Physics and Astronomy , Dartmouth
TLS and photogrammetry for the modeling of a historic wooden framework
NASA Astrophysics Data System (ADS)
Koehl, M.; Viale, M.
2012-04-01
The building which is the object of the study is located in the center of Andlau, France. This mansion that was built in 1582 was the residence of the Lords of Andlau from the XVIth century until the French Revolution. Its architecture represents the Renaissance style of the XVIth century in particular by its volutes and its spiral staircase inside the polygonal turret. In January 2005, the municipality of Andlau became the owner of this Seigneury which is intended to welcome the future Heritage Interpretation Center (HIC), a museum is also going to be created there. Three levels of attic of this building are going to be restored and isolated, the historic framework will that way be masked and the last three levels will not be accessible any more. In this context, our lab was asked to model the framework to allow to make diagnoses there, to learn to know and to consolidate the knowledge on this type of historic framework. Finally, next to a virtual visualization, we provided other applications in particular the creation of an accurate 3D model of the framework for animations, as well as for foundation of an historical information system and for supplying the future museum and HIC with digital data. The project contains different phases: the data acquisition, the model creation and data structuring, the creation of an interactive model and the integration in a historic information system. All levels of the attic were acquired: a 3D Trimble GX scanner and partially a Trimble CX scanner were used in particular for the acquisition of data in the highest part of the framework. The various scans were directly georeferenced in the field thanks to control points, then merged together in an unique point cloud covering the whole structure. Several panoramic photos were also realized to create a virtual tour of the framework and the surroundings of the Seigneury. The purpose of the project was to supply a 3D model allowing the creation of scenographies and interactive contents which will be integrated into an informative device. That way, the public can easily visualize the framework, manipulate the 3D model, discover the construction and the various parts of the historical wooden structure. The raw point cloud cannot be used for this kind of applications. It is thus necessary, from the data which it supplies, to create an exploitable model. Several parameters are to be taken into account: the level of detail of the 3D model, the necessary time to model all the beams, the weight of the final files and finally the type of applied texture. The idea was to implement a workflow to reconcile these various criteria, several methods were tested. This project allowed to create a range of solutions (3D models of the complete framework, virtual tour, interactive 3D models, video animations) to allow an uninitiated public to take advantage of 3D material and software often reserved for the professionals. The work was completed by the comparison between a theoretical model of the framework and a more detailed model of the current state, which allowed to make diagnoses and to study the movements of the structure in the time and to supply important data for rehabilitation and renovation operations.
Effects of PCB exposure on neuropsychological function in children.
Schantz, Susan L; Widholm, John J; Rice, Deborah C
2003-03-01
In the last decade advances in the analytic methods for quantification of polychlorinated biphenyls (PCBs) have resulted in widespread availability of congener-specific analysis procedures, and large amounts of data on PCB congener profiles in soil, air, water, sediments, foodstuffs, and human tissues have become available. These data have revealed that the PCB residues in environmental media and human tissues may not closely resemble any of the commercial PCB mixtures, depending on source of exposure, bioaccumulation through the food chain, and weathering of PCBs in the environment. At the same time, toxicological research has led to a growing awareness that different classes of PCB congeners have different profiles of toxicity. These advances in analytic techniques and toxicological knowledge are beginning to influence the risk assessment process. As the data from ongoing PCB studies assessing the mediators of neurobehavioral outcomes in children are published, the weight of evidence for PCB effects on neurodevelopment is growing. Studies in Taiwan, Michigan (USA), New York (USA), Holland, Germany, and the Faroe Islands have all reported negative associations between prenatal PCB exposure and measures of cognitive functioning in infancy or childhood. The German study also reported a negative association between postnatal PCB exposure and cognitive function in early childhood--a result that had not been found in previous studies. Only one published study in North Carolina (USA) has failed to find an association between PCB exposure and cognitive outcomes. Despite the fact that several more recent studies have used congener-specific analytic techniques, there have been only limited attempts to assess the role of specific PCB congeners or classes of congeners in mediating neurodevelopmental outcomes. From a statistical standpoint, attempts to determine the role of individual congeners in mediating outcomes are hampered by the fact that concentrations of most individual congeners are highly correlated with each other and with total PCBs. From a toxicological standpoint, these efforts are hampered by the fact that many of the PCB congeners present in human tissues have never been studied in the laboratory, and their relative potency to produce nervous system effects is unknown. More complete information on the health effects of various congeners or congener classes would allow more informed scientific and risk assessment decisions.
Saladino, Raffaele; Botta, Giorgia; Bizzarri, Bruno Mattia; Di Mauro, Ernesto; Garcia Ruiz, Juan Manuel
2016-05-17
The pathway from simple abiotically made organic compounds to the molecular bricks of life, as we know it, is unknown. The most efficient geological abiotic route to organic compounds results from the aqueous dissolution of olivine, a reaction known as serpentinization (Sleep, N.H., et al. (2004) Proc. Natl. Acad. Sci. USA 101, 12818-12822). In addition to molecular hydrogen and a reducing environment, serpentinization reactions lead to high-pH alkaline brines that can become easily enriched in silica. Under these chemical conditions, the formation of self-assembled nanocrystalline mineral composites, namely silica/carbonate biomorphs and metal silicate hydrate (MSH) tubular membranes (silica gardens), is unavoidable (Kellermeier, M., et al. In Methods in Enzymology, Research Methods in Biomineralization Science (De Yoreo, J., Ed.) Vol. 532, pp 225-256, Academic Press, Burlington, MA). The osmotically driven membranous structures have remarkable catalytic properties that could be operating in the reducing organic-rich chemical pot in which they form. Among one-carbon compounds, formamide (NH2CHO) has been shown to trigger the formation of complex prebiotic molecules under mineral-driven catalytic conditions (Saladino, R., et al. (2001) Biorganic & Medicinal Chemistry, 9, 1249-1253), proton irradiation (Saladino, R., et al. (2015) Proc. Natl. Acad. Sci. USA, 112, 2746-2755), and laser-induced dielectric breakdown (Ferus, M., et al. (2015) Proc Natl Acad Sci USA, 112, 657-662). Here, we show that MSH membranes are catalysts for the condensation of NH2CHO, yielding prebiotically relevant compounds, including carboxylic acids, amino acids, and nucleobases. Membranes formed by the reaction of alkaline (pH 12) sodium silicate solutions with MgSO4 and Fe2(SO4)3·9H2O show the highest efficiency, while reactions with CuCl2·2H2O, ZnCl2, FeCl2·4H2O, and MnCl2·4H2O showed lower reactivities. The collections of compounds forming inside and outside the tubular membrane are clearly specific, demonstrating that the mineral self-assembled membranes at the same time create space compartmentalization and selective catalysis of the synthesis of relevant compounds. Rather than requiring odd local conditions, the prebiotic organic chemistry scenario for the origin of life appears to be common at a universal scale and, most probably, earlier than ever thought for our planet.
78 FR 14400 - Southern USA Resources, Inc., Order of Suspension of Trading
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-05
... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Southern USA Resources, Inc., Order of... lack of current and accurate information concerning the securities of Southern USA Resources, Inc. (``Southern USA'') because of questions regarding the accuracy of publicly-disseminated information concerning...
Maholtz, Danielle E; Erickson, Michael J; Cymet, Tyler
2015-04-01
The Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) assesses the competence of osteopathic physicians in training. It is designed to protect the public by setting minimum competence standards. All osteopathic medical students must pass COMLEX-USA Level 1, Level 2-Cognitive Evaluation, and Level 2-Performance Evaluation before being allowed to graduate from an osteopathic medical school. Residency training programs use COMLEX-USA scores as a major factor in deciding whom they will interview and admit into their programs. In addition, colleges of osteopathic medicine use student COMLEX-USA scores as an external assessment of their success in educating students. Because COMLEX-USA is a high-stakes examination series, it is important to understand predictive factors for performance. The authors review the literature on the relationship between COMLEX-USA scores and correlated student variables. Results from the Council on Osteopathic Student Government Presidents' survey on students' preparation methods and performance are also provided.
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2013-04-30
..., USA, Inc., Oncology Care Systems (Radiation Oncology), Including On-Site Leased Workers From Source... Medical Solutions, USA, Inc., Oncology Care Systems (Radiation Oncology), including on- site leased... of February 2013, Siemens Medical Solutions, USA, Inc., Oncology Care Systems (Radiation Oncology...
Lukas, Rimas V; Wainwright, Derek A; Laterra, John J
2016-01-01
American Neurological Association Annual Meeting, Chicago, IL, USA, 27-29 September 2015 The American Neurological Association (ANA) held its annual meeting in Chicago, IL, USA on 27-29 September 2015. The Scientific Programming Advisory Committee was chaired by Dr. S Pleasure from the University of California-San Francisco (CA, USA). The Neuro-Oncology session, chaired by Dr. A Pruitt from the University of Pennsylvania (PA, USA) and cochaired by Dr. J Laterra from Johns Hopkins University (MD, USA), was held on 27 September 2015. Speakers included Dr. D Wainwright (Northwestern University, IL, USA), Dr. N Kolb (University of Utah, UT, USA), Dr. A Nath (NINDS/NIH, MD, USA), Dr. D Franz (Cincinnati Children's Hospital, OH, USA) and Dr. R Lukas (University of Chicago, IL, USA). A summary of key presentations from the Neuro-Oncology section of the 2015 American Neurological Association annual meeting is reported. Preclinical and clinical advances in the use of immunotherapies for the treatment of primary and metastatic CNS tumors are covered. Particular attention is paid to the enzyme indoleamine dioxygenase and the immune checkpoints CTLA4 and PD1 and their ligands. Specific nervous system toxicities associated with novel immunotherapies are also discussed. The recent success of targeting the mTOR pathway in the neurocutaneous syndrome tuberous sclerosis is detailed. Finally, important early steps in our understanding of the common toxicity of chemotherapy induced neuropathy are reviewed.
Immergluck, Lilly Cheng; Jain, Shabnam; Ray, Susan M.; Mayberry, Robert; Satola, Sarah; Parker, Trisha Chan; Yuan, Keming; Mohammed, Anaam; Jerris, Robert C.
2017-01-01
Introduction The purpose of this study was to examine community-associated methicillin resistant Staphylococcus aureus (CA-MRSA) carriage and infections and determine risk factors associated specifically with MRSA USA300. Methods We conducted a case control study in a pediatric emergency department. Nasal and axillary swabs were collected, and participants were interviewed for risk factors. The primary outcome was the proportion of S. aureus carriers among those presenting with and without a skin and soft tissue infection (SSTI). We further categorized S. aureus carriers into MRSA USA300 carriers or non-MRSA USA300 carriers. Results We found the MRSA USA300 carriage rate was higher in children less than two years of age, those with an SSTI, children with recent antibiotic use, and those with a family history of SSTI. MRSA USA300 carriers were also more likely to have lower income compared to non-MRSA USA300 carriers and no S. aureus carriers. Rates of Panton-Valentine leukocidin (PVL) genes were higher in MRSA carriage isolates with an SSTI, compared to MRSA carriage isolates of patients without an SSTI. There was an association between MRSA USA300 carriage and presence of PVL in those diagnosed with an abscess. Conclusion Children younger than two years were at highest risk for MRSA USA300 carriage. Lower income, recent antibiotic use, and previous or family history of SSTI were risk factors for MRSA USA300 carriage. There is a high association between MRSA USA300 nasal/axillary carriage and presence of PVL in those with abscesses. PMID:28210352
28 CFR 16.81 - Exemption of United States Attorneys Systems-limited access.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Systems-limited access. 16.81 Section 16.81 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR... (g): (1) Citizen Complaint Files (JUSTICE/USA-003). (2) Civil Case Files (JUSTICE/USA-005). (3) Consumer Complaints (JUSTICE/USA-006). (4) Criminal Case Files (JUSTICE/USA-007). (5) Kline-District of...
76 FR 35715 - Establishment of the SelectUSA Initiative
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2011-06-20
... Establishment of the SelectUSA Initiative By the authority vested in me as President by the Constitution and the... unnecessary obstacles to investment. Sec. 2. SelectUSA Initiative. (a) Establishment. There is established the SelectUSA Initiative (Initiative), a Government-wide initiative to attract and retain investment in the...
The Science and Technologies for Fusion Energy With Lasers and Direct-Drive Targets
2010-04-01
Commonwealth Technology, Inc ., Alexandria, VA 22315 USA. A. Bayramian, J. Caird, C. Ebbers, J. Latkowski, W. Hogan, W. R. Meier, L. J. Perkins, and K...USA. M. W. McGeoch is with PLEX Corporation, Brookline, MA 02146 USA. S. C. Glidden and H. Sanders are with Applied Pulsed Power, Inc ., Freeville, NY...13068-0348 USA. D. Weidenheimer, D. Morton, and I. D. Smith are with L3 Pulse Sciences, Inc ., San Leandro, CA 94577-5602 USA. M. Bobecia and D. Harding
Airborne surveys of USA urban areas at 121.5/243 MHz
NASA Technical Reports Server (NTRS)
Taylor, R. E.; Hill, J. S.
1979-01-01
In situ, aircraft flight measurements were made in 1976 and 1977 by NASA of the radio-frequency environment over USA urban areas within the emergency distress search and rescue frequency bands at 121.5 and 243.0 MHz. This paper analyzes test results reported previously for USA East Coast and Midwest flight surveys; presented also are test results obtained in May 1977 for the USA West Coast during the NASA, ASSESS-II, Space Shuttle/Spacelab simulation aircraft flights. The USA West Coast flight include data at 121.5/243 MHz during an extensive series of aircraft passes for the Los Angeles urban area. The USA East Coast/Midwest measurements show correlation with population count.
DNA damage and external lesions in brown bullheads (Ameiurus nebulosus) from contaminated habitats
Yang, X.; Meier, J.; Chang, L.; Rowan, M.; Baumann, P.C.
2006-01-01
The Comet assay was used to compare levels of DNA damage in brown bullheads (Ameiurus nebulosus) collected from three known contaminated locations, the Cuyahoga River (OH, USA), Ashtabula River (OH, USA; both tributaries to Lake Erie, USA), and Ashumet Pond (Cape Cod, MA, USA), with brown bullheads collected from three paired reference sites, Old Woman Creek (OH, USA), Conneaut River (OH, USA; both tributaries to Lake Erie), and Great Herring Pond (mainland MA, USA), respectively. Blood was sampled from each fish, and the Comet assay was conducted on erythrocytes. The assay results demonstrate that fish from the three contaminated sites each suffered higher DNA damage compared with fish from their respective reference sites. The results also show that the genetic damage was associated with the occurrence of external lesions and deformities in fish. The Comet assay is sufficiently sensitive to detect exposure of natural fish populations to environmental levels of genotoxic contaminants. ?? 2006 SETAC.
Controlling imported malaria cases in the United States of America.
Dembele, Bassidy; Yakubu, Abdul-Aziz
2017-02-01
We extend the mathematical malaria epidemic model framework of Dembele et al. and use it to ``capture" the 2013 Centers for Disease Control and Prevention (CDC) reported data on the 2011 number of imported malaria cases in the USA. Furthermore, we use our ``fitted" malaria models for the top 20 countries of malaria acquisition by USA residents to study the impact of protecting USA residents from malaria infection when they travel to malaria endemic areas, the impact of protecting residents of malaria endemic regions from mosquito bites and the impact of killing mosquitoes in those endemic areas on the CDC number of imported malaria cases in USA. To significantly reduce the number of imported malaria cases in USA, for each top 20 country of malaria acquisition by USA travelers, we compute the optimal proportion of USA international travelers that must be protected against malaria infection and the optimal proportion of mosquitoes that must be killed.
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... and Order Granting a Waiver to Mitsubishi Electric & Electronics USA, Inc. From the Department of... Mitsubishi Electric & Electronics USA, Inc. (Mitsubishi) a waiver from the existing DOE test procedures... Matter of: Mitsubishi Electric & Electronics USA, Inc. (Mitsubishi) (Case No. CAC-030). Background Title...
76 FR 50269 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance
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2011-08-12
... Solutions USA, Inc., Oncology Care Systems Division, Concord, CA TA-W-73,158A Siemens Medical Solutions USA... and former workers of Siemens Medical Solutions USA, Inc. (Seimens), Oncology Care Systems Division... issued as follows: All workers of Siemens Medical Solutions USA, Inc., Oncology Care Systems Division...
78 FR 30333 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (Usa), Llc.
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2013-05-22
...; Notice of Registration; Siegfried (Usa), Llc. By Notice dated November 19, 2012, and published in the Federal Register on November 27, 2012, 77 FR 70825, Siegfried (USA), LLC., 33 Industrial Park Road... 21 U.S.C. 823(a) and determined that the registration of Siegfried (USA), LLC., to manufacture the...
77 FR 30027 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (USA)
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2012-05-21
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78 FR 64020 - Manufacturer of Controlled Substances, Notice of Registration, Siegfried USA, LLC
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2013-10-25
..., Notice of Registration, Siegfried USA, LLC The Notice dated July 23, 2013, and published in the Federal Register on August 1, 2013, 78 FR 46613, page 18338, Siegfried (USA), LLC., 33 Industrial Park Road...), and Poppy Straw Concentrate (9670). On August 6, 2013, Siegfried (USA), LLC., subsequently withdrew...
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2012-12-26
... CONSUMER PRODUCT SAFETY COMMISSION [CPSC Docket No. 13-2] Star Networks USA, LLC; Complaint AGENCY.... Published below is a Complaint: In the Matter of Star Networks USA, LLC.\\1\\ \\1\\ Chairman Inez M. Tenenbaum... COMMISSION In the Matter of STAR NETWORKS USA, LLC, Respondent CPSC DOCKET NO. 13-2 COMPLAINT Nature of...
76 FR 29257 - Accreditation of Intertek USA, Inc., as a Commercial Laboratory
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2011-05-20
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77 FR 75183 - Approval of Intertek USA, Inc., as a Commercial Gauger
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2012-12-19
... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Approval of Intertek USA, Inc.... ACTION: Notice of approval of Intertek USA, Inc., as a commercial gauger. SUMMARY: Notice is hereby given that, pursuant to 19 CFR 151.13, Intertek USA, Inc., 139 Castle Coakley, Suite 8, St. Croix, VI 00820...
GLIMPSE: A GCAM-USA-based tool for supporting coordinated energy and environmental planning
GCAM-USA is an integrated assessment model, meaning that it simulates the interactions among human and earth systems. GCAM-USA is derived from GCAM, which represents the U.S. as one region within a 32-region global model. GCAM-USA subdivides the U.S. region into 50 states and the...
Origin, evolution, and global transmission of community-acquired Staphylococcus aureus ST8
Strauß, Lena; Alabi, Abraham; Breurec, Sebastien; Coombs, Geoffrey; Egyir, Beverly; Larsen, Anders Rhod; Laurent, Frederic; Monecke, Stefan; Peters, Georg; Skov, Robert; Strommenger, Birgit; Schaumburg, Frieder
2017-01-01
USA300 is a pandemic clonal lineage of hypervirulent, community-acquired, methicillin-resistant Staphylococcus aureus (CA-MRSA) with specific molecular characteristics. Despite its high clinical relevance, the evolutionary origin of USA300 remained unclear. We used comparative genomics of 224 temporal and spatial diverse S. aureus isolates of multilocus sequence type (ST) 8 to reconstruct the molecular evolution and global dissemination of ST8, including USA300. Analyses of core SNP diversity and accessory genome variations showed that the ancestor of all ST8 S. aureus most likely emerged in Central Europe in the mid-19th century. From here, ST8 was exported to North America in the early 20th century and progressively acquired the USA300 characteristics Panton–Valentine leukocidin (PVL), SCCmec IVa, the arginine catabolic mobile element (ACME), and a specific mutation in capsular polysaccharide gene cap5E. Although the PVL-encoding phage ϕSa2USA was introduced into the ST8 background only once, various SCCmec types were introduced to ST8 at different times and places. Starting from North America, USA300 spread globally, including Africa. African USA300 isolates have aberrant spa-types (t112, t121) and form a monophyletic group within the clade of North American USA300. Large parts of ST8 methicillin-susceptible S. aureus (MSSA) isolated in Africa represent a symplesiomorphic group of ST8 (i.e., a group representing the characteristics of the ancestor), which are rarely found in other world regions. Isolates previously discussed as USA300 ancestors, including USA500 and a “historic” CA-MRSA from Western Australia, were shown to be only distantly related to recent USA300 clones. PMID:29158405
Pritchard, Colin; Rosenorn-Lanng, Emily
2015-01-01
Have USA total neurological deaths (TNDs) of adults (55-74) and the over 75's risen more than in twenty Western Countries? World Health Organization TND data are compared with control mortalities cancer mortality rates (CMRs) and circulatory disease deaths (CDDs) between 1989-1991 and 2008-2010 and odds ratios (ORs) and confidence intervals calculated. Neurological Deaths - Twenty country (TC) average 55-74 male rates per million (pm) rose 2% to 503 pm, USA increased by 82% to 627 pm. TC average females rose 1% to 390 pm, USA rising 48% to 560 pm. TC average over 75's male and female increased 117% and 143%; USA rising 368% and 663%, significantly more than 16 countries. Cancer mortality - Average 55-74 male and female fell 20% and 12%, USA down 36% and 18%. TC average over 75's male and female fell 13% and 15%, the USA 29% and 2%. Circulatory deaths - TC average 55-74 rates fell 60% and 46% the USA down 54% and 53%. Over 75's average down 46% and 39%, USA falling 40% and 33%. ORs for rose substantially in every country. TC average 75's ORs for CMR: TND male and females were 1:2.83 and 1:3.04 but the USA 1:5.18 and 1:6.50. The ORs for CDD: TND male and females TC average was 1:3.42 and 1:3.62 but the USA 1:6.13 and 1:9.89. Every country's neurological deaths rose relative to the controls, especially in the USA, which is a cause for concern and suggests possible environmental influences.
Pesticide exposures and chronic kidney disease of unknown etiology: an epidemiologic review.
Valcke, Mathieu; Levasseur, Marie-Eve; Soares da Silva, Agnes; Wesseling, Catharina
2017-05-23
The main causes of chronic kidney disease (CKD) globally are diabetes and hypertension but epidemics of chronic kidney disease of unknown etiology (CKDu) occur in Central America, Sri Lanka, India and beyond. Althoug also being observed in women, CKDu concentrates among men in agricultural sectors. Therefore, suspicions fell initially on pesticide exposure, but currently chronic heat stress and dehydration are considered key etiologic factors. Responding to persistent community and scientific concerns about the role of pesticides, we performed a systematic review of epidemiologic studies that addressed associations between any indicator of pesticide exposure and any outcome measure of CKD. Of the 21 analytical studies we identified, seven were categorized as with low, ten with medium and four with relatively high explanation value. Thirteen (62%) studies reported one or more positive associations, but four had a low explanation value and three presented equivocal results. The main limitations of both positive and negative studies were unspecific and unquantified exposure measurement ('pesticides'), the cross-sectional nature of most studies, confounding and selection bias. The four studies with stronger designs and better exposure assessment (from Sri Lanka, India and USA) all showed exposure-responses or clear associations, but for different pesticides in each study, and three of these studies were conducted in areas without CKDu epidemics. No study investigated interactions between pesticides and other concommittant exposures in agricultural occupations, in particular heat stress and dehydration. In conclusion, existing studies provide scarce evidence for an association between pesticides and regional CKDu epidemics but, given the poor pesticide exposure assessment in the majority, a role of nephrotoxic agrochemicals cannot be conclusively discarded. Future research should procure assessment of lifetime exposures to relevant specific pesticides and enough power to look into interactions with other major risk factors, in particular heat stress.
Lehman, Vance T; Barrick, Benjamin J; Pittelkow, Mark R; Peller, Patrick J; Camilleri, Michael J; Lehman, Julia S
2015-04-01
The utility of diagnostic imaging in paraneoplastic autoimmune multiorgan syndrome (PAMS) is unknown. We examined the role of diagnostic imaging in patients with PAMS evaluated at our tertiary referral center (at Mayo Clinic, Rochester, MN, USA) and in the English literature between January 1, 1996, and August 31, 2012. We included 17 patients from our institution and 208 patients from the literature review. Of these 225 patients, 113 (50.2%) were not known to have a malignancy diagnosis at the time of PAMS diagnosis. Of the 123 patients from our institution and from the literature reported to undergo imaging studies, conventional computed tomography (CT) was the predominant imaging modality (n = 110; 89.4%); 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT was also used, albeit infrequently (n = 12; 9.8%). When CT was included in imaging to identify or confirm the presence of a malignancy, imaging was successful in all patients who ultimately were diagnosed with an associated malignancy. At our institution, a relatively high percentage (n = 7; 41%) of patients had 18F-FDG PET/CT, which not only identified all tumors found on CT but also facilitated staging of lymphoma and guided biopsy procedures. Diagnostic imaging is frequently utilized in PAMS with unknown malignancy. Both conventional CT and 18F-FDG PET/CT are likely to detect the typical underlying neoplasms. Relative to conventional CT, 18F-FDG PET/CT may provide additional useful information regarding prognosis for the likely underlying malignancies, although there is a paucity of reports describing the use of this modality for this purpose. © 2014 The International Society of Dermatology.
Müller von der Grün, Jens; Bon, Dimitra; Rödel, Claus; Balermpas, Panagiotis
2018-05-14
Due to the absence of randomized trials, the optimal management for squamous cell cancer of unknown primary in the head and neck region (SCCHN CUP) remains controversial. Current strategies are based on retrospective studies, clinical experience, and institutional policies. An anonymous questionnaire with a total of 24 questions was created and distributed by the use of an online version (Google Forms®, Google, Mountain View, CA, USA) as well as a printout version as equivalent option. An email with a link to the survey and the questionnaire as attachment was sent to 361 DEGRO(German Society of Radiation Oncology)-associated departments. Frequency distributions of responses for each question were calculated. The data were also analyzed by type of practice. Representativity of the sample size for the DEGRO was also evaluated. 66 responses were received including answers from 20 (30%) university departments, 16 (24%) non-university institutions, and 30 (46%) radiation oncology practices. 95% of the participants routinely present these cases in an interdisciplinary tumor board and use intensity modulated radiotherapy (IMRT) techniques for SCCHN CUP treatment. Surgery includes neck dissection in 83% and tonsillectomy in 73% of the cases. Human papilloma virus (HPV) status is routinely determined in 82% of the departments. Statistically significant differences between universities and institutions and clinics and practices could be found with respect to positron emission tomography-computed tomography (PET-CT) utilization, indications for chemotherapy, radiotherapy volumes, and cumulative doses. Diagnostics and treatment for SCCHN CUP within the DEGRO remain heterogeneous. A prospective register trial with standard operation procedures is warranted to homogenize and possibly improve management.
Schlueter, Rabea; Röder, Anja; Czekalski, Nadine; Gliesche, Daniel; Mikolasch, Annett; Schauer, Frieder
2014-01-01
The compound p-tert-amylphenol (p-(1,1-dimethylpropyl)phenol) is a widely used disinfectant belonging to the group of short branched-chain alkylphenols. It is produced in or imported into the USA with more than one million pounds per year and can be found in the environment in surface water, sediments, and soil. We have investigated for the first time the biotransformation of this disinfectant and the accumulation of metabolites by five bacterial strains, three yeast strains, and three filamentous fungi, selected because of their ability to transform either aromatic or branched-chain compounds. Of the 11 microorganisms tested, one yeast strain and three bacteria could not transform the disinfectant despite of a very low concentration applied (0.005%). None of the other seven organisms was able to degrade the short branched alkyl chain of p-tert-amylphenol. However, two yeast strains, two filamentous fungi, and two bacterial strains attacked the aromatic ring system of the disinfectant via the hydroxylated intermediate 4-(1,1-dimethyl-propyl)-benzene-1,2-diol resulting in two hitherto unknown ring fission products with pyran and furan structures, 4-(1,1-dimethyl-propyl)-6-oxo-6-H-pyran-2-carboxylic acid and 2-[3-(1,1-dimethyl-propyl)-5-oxo-2H-furan-2-yl]acetic acid. While the disinfectant was toxic to the organisms applied, one of the ring cleavage products was not. Thus, a detoxification of the disinfectant was achieved by ring cleavage. Furthermore, one filamentous fungus formed sugar conjugates with p-tert-amylphenol as another mechanism of detoxification of toxic environmental pollutants. With this work, we can also contribute to the allocation of unknown chemical compounds within environmental samples to their parent compounds.
Tomiyama, Hiroyuki; Li, Yuanzhe; Yoshino, Hiroyo; Mizuno, Yoshikuni; Kubo, Shin-Ichiro; Toda, Tatsushi; Hattori, Nobutaka
2009-05-22
DJ-1 mutations cause autosomal recessive parkinsonism (ARP). Although some reports of DJ-1 mutations have been published, there is lack of information on the prevalence of these mutations in large-scale studies of both familial and sporadic parkinsonism. In this genetic screening study, we analyzed the distribution and frequency of DJ-1 mutations by direct nucleotide sequencing of coding exons and exon-intron boundaries of DJ-1, in 386 parkin-negative parkinsonism patients (371 index cases: 67 probands of autosomal recessive parkinsonism families, 90 probands of autosomal dominant parkinsonism families, 201 patients with sporadic parkinsonism, and 13 with unknown family histories) from 12 countries (Japan 283, China 27, Taiwan 22, Korea 22, Israel 16, Turkey 5, Philippines 2, Bulgaria 2, Greece 2, Tunisia 1, USA 2, Ukraine 1, unknown 1). None had causative mutation in DJ-1, suggesting DJ-1 mutation is very rare among patients with familial and sporadic parkinsonism from Asian countries and those with other ethnic background. This is in contrast to the higher frequencies and worldwide distribution of parkin- and PINK1-related parkinsonism in ARP and sporadic parkinsonism. Thus, after obtaining clinical information, screening for mutations in (1) parkin, (2) PINK1, (3) DJ-1, (4) ATP13A2 should be conducted in that order, in ARP and sporadic parkinsonism, based on their reported frequencies. In addition, haplotype analysis should be employed to check for homozygosity of 1p36, which harbors a cluster of causative genes for ARP such as DJ-1, PINK1 and ATP13A2 in ARP and sporadic parkinsonism, especially in parkinsonism with consanguinity.
Zaccardi, Francesco; Dhalwani, Nafeesa N; Webb, David R; Davies, Melanie J; Khunti, Kamlesh
2018-07-01
In the context of increasing prevalence of diabetes in elderly people with multimorbidity, intensive glucose control may increase the risk of severe hypoglycaemia, potentially leading to death. While rising trends of severe hypoglycaemia rates have been reported in some European, North American and Asian countries, the global burden of hypoglycaemia-related mortality is unknown. We aimed to investigate global differences and trends of hypoglycaemia-related mortality. We used the WHO mortality database to extract information on death certificates reporting hypoglycaemia or diabetes as the underlying cause of death, and the United Nations demographic database to obtain data on mid-year population estimates from 2000 to 2014. We calculated crude and age-standardised proportions (defined as number of hypoglycaemia-related deaths divided by total number of deaths from diabetes [i.e. the sum of hypoglycaemia- and diabetes-related deaths]) and rates (hypoglycaemia-related deaths divided by mid-year population) of hypoglycaemia-related mortality and compared estimates across countries and over time. Data for proportions were extracted from 109 countries (31 had data from all years analysed [2000-2014] available). Combining all countries, the age-standardised proportion of hypoglycaemia-related deaths was 4.49 (95% CI 4.44, 4.55) per 1000 total diabetes deaths. Compared with the overall mean, most Central American, South American and (mainly) Caribbean countries reported higher proportions (five more age-standardised hypoglycaemia-related deaths per 1000 total diabetes deaths in Chile, six in Uruguay, 11 in Belize and 22 in Aruba), as well as Japan (11 more age-standardised hypoglycaemia-related deaths per 1000 total diabetes deaths). In comparison, lower proportions were noted in most European countries, the USA, Canada, New Zealand and Australia. For countries with data available for all years analysed, trend analysis showed a 60% increase in hypoglycaemia-related deaths until 2010 and stable trends onwards. Rising trends were most evident for Argentina, Brazil, Chile, the USA and Japan. Data for rates were available for 105 countries (30 had data for all years analysed [2000-2014] available). Combining all countries, the age-standardised hypoglycaemia-related death rate was 0.79 (95% CI 0.77, 0.80) per 1 million person-years. Most Central American, South American and Caribbean countries similarly reported higher rates of hypoglycaemia-related death, whilst virtually all European countries, the USA, Canada, Japan, New Zealand and Australia reported lower rates compared with the overall mean. Age-standardised rates were very low for most countries (lower than five per 1 million person-years in 89.5% of countries), resulting in small absolute differences among countries. As noted with the proportions analysis, trend analysis showed an overall 60% increase in hypoglycaemia-related deaths until 2010 and stable rate trends onwards; rising rates were particularly evident for Brazil, Chile and the USA. Most countries in South America, Central America and the Caribbean showed the highest proportions of diabetes-related deaths attributable to hypoglycaemia and the highest rates of hypoglycaemia-related deaths. Between 2000 and 2014, rising trends were observed in Brazil, Chile and the USA for both rates and proportions of hypoglycaemia-related death, and in Argentina and Japan for proportions only. Further studies are required to unravel the contribution of clinical and socioeconomic factors, difference in diabetes prevalence and heterogeneity of death certification in determining lower rates and proportions of hypoglycaemia-related deaths in high-income countries in Europe, North America and Asia. Data used for these analyses are available at https://doi.org/10.17632/ndp52fbz8r.1.
Klippel-Feil syndrome associated with atrial septal defect.
Bejiqi, Ramush; Retkoceri, Ragip; Bejiqi, Hana; Zeka, Naim; Maloku, Arlinda; Berisha, Majlinda
2013-01-01
Three major features result from this abnormality: a short neck, a limited range of motion in the neck, and a low hairline at the back of the head. Most affected people have one or two of these characteristic features. Less than half of all individuals with Klippel-Feil syndrome have all three classic features of this condition. The etiology of Klippel-Feil syndrome and its associated conditions is unknown. The syndrome can present with a variety of other clinical syndromes, including fetal alcohol syndrome, Goldenhar syndrome, anomalies of the extremities etc. Associated anomalies occur in the auditory system, neural axis, cardiovascular system, and the musculoskeletal system. Cardiovascular anomalies, mainly septal defects, were found in 7 patients in Hensinger's series, with 4 of these individuals requiring corrective surgery. In our case we have had registered a nonrestrictive atrial septal defect and corrective surgical intervention at age 18 months in the Santa Rosa Children's Hospital (USA) has been done successfully. Careful examinations of specialist exclude anomalies in other organs and systems. Radiographs and MRI of the thoracic and lumbosacral spine are obtained and other anomalies have been excluded.
The mirage effect to probe the adsorption of organic molecules on the surface of the mass standards
NASA Astrophysics Data System (ADS)
Taillade, F.; Silva, M. Z.; Lepoutre, F.; Lecollinet, M.; Pinot, P.
2000-05-01
Among all the basic SI units, the mass unit is the only one to be defined in terms of a material standard: a prototype called K. All the industrial countries possess their own standards which were compared to the K during the last international comparison showing that unknown evolution occurs, but the adsorption-desorption of cleaning products plays a relatively important role. A few years ago, several laboratories in the U.S.A., Germany, and France reported interesting results of photothermal measurements to detect desorption at normal temperature and pressure (NTP). This paper presents a mirage set-up built to detect the film of condensable gasses on metallic surfaces at NTP conditions. In order to quantify these measurements, an inverse method has been developed to determine the adsorption isotherm involved in the physical process of adsorption-desorption and the linked parameters such as absorbability, type of adsorption, and differential heat of adsorption. The results will be discussed to imagine possible tracks to reduce the instabilities of the standards in the future and for possible new definitions of standards built with silicon.
Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2.
Corzo, Gerardo; Bernard, Cedric; Clement, Herlinda; Villegas, Elba; Bosmans, Frank; Tytgat, Jan; Possani, Lourival D; Darbon, Herve; Alagón, Alejandro
2009-08-01
Soluble venom and purified fractions of the theraposid spider Brachypelma albiceps were screened for insecticidal peptides based on toxicity to crickets. Two insecticidal peptides, named Ba1 and Ba2, were obtained after the soluble venom was separated by high performance liquid chromatography and cation exchange chromatography. The two insecticidal peptides contain 39 amino acid residues and three disulfide bonds, and based on their amino acid sequence, they are highly identical to the insecticidal peptides from the theraposid spiders Aphonopelma sp. from the USA and Haplopelma huwenum from China indicating a relationship among these genera. Although Ba1 and Ba2 were not able to modify currents in insect and vertebrate cloned voltage-gated sodium ion channels, they have noteworthy insecticidal activities compared to classical arachnid insecticidal toxins indicating that they might target unknown receptors in insect species. The most abundant insecticidal peptide Ba2 was submitted to NMR spectroscopy to determine its 3-D structure; a remarkable characteristic of Ba2 is a cluster of basic residues, which might be important for receptor recognition.
Horton, B.P.; Milker, Yvonne; Dura, T.; Wang, Kelin; Bridgeland, W.T.; Brophy, Laura S.; Ewald, M.; Khan, Nicole; Engelhart, S.E.; Nelson, Alan R.; Witter, Robert C.
2017-01-01
Comparisons of pre-earthquake and post-earthquake microfossils in tidal sequences are accurate means to measure coastal subsidence during past subduction earthquakes, but the amount of subsidence is uncertain, because the response times of fossil taxa to coseismic relative sea-level (RSL) rise are unknown. We measured the response of diatoms and foraminifera to restoration of a salt marsh in southern Oregon, USA. Tidal flooding following dike removal caused an RSL rise of ∼1 m, as might occur by coseismic subsidence during momentum magnitude (Mw) 8.1–8.8 earthquakes on this section of the Cascadia subduction zone. Less than two weeks after dike removal, diatoms colonized low marsh and tidal flats in large numbers, showing that they can record seismically induced subsidence soon after earthquakes. In contrast, low-marsh foraminifera took at least 11 months to appear in sizeable numbers. Where subsidence measured with diatoms and foraminifera differs, their different response times may provide an estimate of postseismic vertical deformation in the months following past megathrust earthquakes.
Rogers, Holly; Schmidt, Travis S.; Dabney, Brittanie L.; Hladik, Michelle; Mahler, Barbara J.; Van Metre, Peter C.
2016-01-01
Direct and indirect ecological effects of the widely used insecticide bifenthrin on stream ecosystems are largely unknown. To investigate such effects, a manipulative experiment was conducted in stream mesocosms that were colonized by aquatic insect communities and exposed to bifenthrin-contaminated sediment; implications for natural streams were interpreted through comparison of mesocosm results to a survey of 100 Midwestern streams, USA. In the mesocosm experiment, direct effects of bifenthrin exposure included reduced larval macroinvertebrate abundance, richness, and biomass at concentrations (EC50s ranged 197.6 – 233.5 ng bifenthrin/ g organic carbon) previously thought safe for aquatic life. Indirect effects included a trophic cascade in which periphyton abundance increased after macroinvertebrate scrapers decreased. Adult emergence dynamics and corresponding terrestrial subsidies were altered at all bifenthrin concentrations tested. Extrapolating these results to the Midwestern stream assessment suggests pervasive ecological effects, with altered emergence dynamics likely in 40% of streams and a trophic cascade in 7% of streams. This study provides new evidence that a common pyrethroid might alter aquatic and terrestrial ecosystem function at the regional scale.
Effects of Silver and Other Metals on the Cytoskeleton
NASA Technical Reports Server (NTRS)
Conrad, Gary W.
1997-01-01
Directly or indirectly, trace concentrations of silver ion (Ag(+)) stabilize microtubules (Conrad, A.H., et al. Cell Motil. & Cytoskel. 27:117-132), as does taxol (Conrad, A.H., et al. J. Exp. Zool. 262:154-165), an effect with major consequences for cellular shape changes and development. Polymerization of microtubules is gravity-sensitive (Tabony and Job, Proc. Natl. Acad. Sci. USA 89:6948-6952), so trace amounts of Ag(+) may alter cellular ability to respond to gravity. If Ag electrolysis is used to purify water on NASA space vehicles, plants and animals/astronauts will be exposed continuously to Ag(+), a regimen with unknown cellular and developmental consequences. Fertilized eggs of the marine mudsnail, Ilyanassa obsoleta, are the cells in which the effects of A(+) on microtubules were discovered. They distribute visible cytoplasmic contents according to gravity and contain cytoplasmic morphogenetic determinants for heart development. The objectives are to determine if the effects of Ag(+), AU(3+), (of biosensor relevance), or Gd(3+) (inhibitor of some stretch-activated ion channels) on the cytoskeleton (in the presence and absence of mechanical loading) will affect cellular responses to gravity.
Collins, D.S.; Nichols, T.C.
1987-01-01
A knowledge of past overburden thickness is useful for designing underground structures such as waste repositories. This study attempts to determine if a correlation can be made between a geologic estimate and two types of geotechnical calculations of past overburden thickness. In the Pierre-Hayes area, Late Cretaceous Pierre Shales is the only bedrock present, but clasts of the Miocene Ogallala Formation were found in the Pleistocene deposits, suggesting that rocks of the Ogallala Formation once covered this area. Based on the geologic estimate, the Ogallala surface was 1100 ft higher than the present surface. Of the two types of geotechnical data acquired for the Hayes site, the laboratory overconsolidation ratios indicate a past overburden thickness value of 2300 ft, whereas the in situ pressuremeter overconsolidation ratios indicate 1318 ft. We, therefore, believe that in situ determination is a better indicator of past overburden that the laboratory results. However, why the two test results differ to this degree is unknown at present.-from Authors
Rogers, Holly A; Schmidt, Travis S; Dabney, Brittanie L; Hladik, Michelle L; Mahler, Barbara J; Van Metre, Peter C
2016-11-01
Direct and indirect ecological effects of the widely used insecticide bifenthrin on stream ecosystems are largely unknown. To investigate such effects, a manipulative experiment was conducted in stream mesocosms that were colonized by aquatic insect communities and exposed to bifenthrin-contaminated sediment; implications for natural streams were interpreted through comparison of mesocosm results to a survey of 100 Midwestern streams, USA. In the mesocosm experiment, direct effects of bifenthrin exposure included reduced larval macroinvertebrate abundance, richness, and biomass at concentrations (EC 50 's ranged from 197.6 to 233.5 ng bifenthrin/g organic carbon) previously thought safe for aquatic life. Indirect effects included a trophic cascade in which periphyton abundance increased after macroinvertebrate scrapers decreased. Adult emergence dynamics and corresponding terrestrial subsidies were altered at all bifenthrin concentrations tested. Extrapolating these results to the Midwestern stream assessment suggests pervasive ecological effects, with altered emergence dynamics likely in 40% of streams and a trophic cascade in 7% of streams. This study provides new evidence that a common pyrethroid might alter aquatic and terrestrial ecosystem function at the regional scale.
Notochord to Nucleus Pulposus Transition.
Lawson, Lisa; Harfe, Brian D
2015-10-01
A tissue that commonly deteriorates in older vertebrates is the intervertebral disc, which is located between the vertebrae. Age-related changes in the intervertebral discs are thought to cause most cases of back pain. Back pain affects more than half of people over the age of 65, and the treatment of back pain costs 50-100 billion dollars per year in the USA. The normal intervertebral disc is composed of three distinct regions: a thick outer ring of fibrous cartilage called the annulus fibrosus, a gel-like material that is surrounded by the annulus fibrosus called the nucleus pulposus, and superior and inferior cartilaginous end plates. The nucleus pulposus has been shown to be critical for disc health and function. Damage to this structure often leads to disc disease. Recent reports have demonstrated that the embryonic notochord, a rod-like structure present in the midline of vertebrate embryos, gives rise to all cell types found in adult nuclei pulposi. The mechanism responsible for the transformation of the notochord into nuclei pulposi is unknown. In this review, we discuss potential molecular and physical mechanisms that may be responsible for the notochord to nuclei pulposi transition.
Recovery of time-dependent volatility in option pricing model
NASA Astrophysics Data System (ADS)
Deng, Zui-Cha; Hon, Y. C.; Isakov, V.
2016-11-01
In this paper we investigate an inverse problem of determining the time-dependent volatility from observed market prices of options with different strikes. Due to the non linearity and sparsity of observations, an analytical solution to the problem is generally not available. Numerical approximation is also difficult to obtain using most of the existing numerical algorithms. Based on our recent theoretical results, we apply the linearisation technique to convert the problem into an inverse source problem from which recovery of the unknown volatility function can be achieved. Two kinds of strategies, namely, the integral equation method and the Landweber iterations, are adopted to obtain the stable numerical solution to the inverse problem. Both theoretical analysis and numerical examples confirm that the proposed approaches are effective. The work described in this paper was partially supported by a grant from the Research Grant Council of the Hong Kong Special Administrative Region (Project No. CityU 101112) and grants from the NNSF of China (Nos. 11261029, 11461039), and NSF grants DMS 10-08902 and 15-14886 and by Emylou Keith and Betty Dutcher Distinguished Professorship at the Wichita State University (USA).
Update on Biologic Therapies for Systemic Lupus Erythematosus.
Borba, Helena Hiemisch Lobo; Funke, Andreas; Wiens, Astrid; Utiyama, Shirley Ramos da Rosa; Perlin, Cássio Marques; Pontarolo, Roberto
2016-07-01
Systemic lupus erythematosus (SLE) is a chronic multisystemic autoimmune disease driven by genetic, hormonal, and environmental factors. Despite the advances in diagnostic and therapeutic approaches in the last decades, SLE still leads to significant morbidity and increased mortality. Although a cure for SLE is still unknown, treatment is required to control acute disease exacerbation episodes (flares), decrease the frequency and severity of subsequent lupus flares, address comorbidities, and prevent end-organ damage. While conventional SLE pharmacotherapy may exhibit suboptimal efficacy and substantial toxicity, a growing knowledge of the disease pathogenesis enabled the research on novel therapeutic agents directed at specific disease-related targets. In this paper, we review the recent progress in the clinical investigation of biologic agents targeting B cells, T cells, cytokines, innate immunity, and other immunologic or inflammatory pathways. Although many investigational agents exhibited insufficient efficacy or inadequate safety in clinical trials, one of them, belimumab, fulfilled the efficacy and safety regulatory requirements and was approved for the treatment of SLE in Europe and the USA, which confirms that, despite all difficulties, advances in this field are possible.
Sankey, Temuulen T.; Sankey, Joel B.; Horne, Rene; Bedford, Ashton
2016-01-01
Tamarisk is an invasive, riparian shrub species in the southwestern USA. The northern tamarisk beetle (Diorhabda carinulata) has been introduced to several states to control tamarisk. We classified tamarisk distribution in the Glen Canyon National Recreation Area, Arizona using a 0.2 m resolution, airborne multispectral data and estimated tamarisk beetle effects (overall accuracy of 86 percent) leading to leaf defoliation in a 49,408 m2 area. We also estimated individual tamarisk tree biomass and their uncertainties using airbonre liday data (100 points/m2). On average, total above ground tamarisk biomass was 8.67 kg/m2 (SD=17.6). The tamarisk beetle defoliation resulted in a mean leaf biomass loss of 0.52 kg/m2 and an equivalent of 25,692 kg across the entire study area. Our defoliated tamarisk map and biomass estimates can help inform restoration treatments to reduce tamarisk. Continued monitoring of tamarisk and tamarisk beetle effects are recommended to understand the currently-unknown eventual equilibrium between the two species and the cascading effects on ecosystem processes.
Hindcast of water availability in regional aquifer systems using MODFLOW Farm Process
Schmid, Wolfgang; Hanson, Randall T.; Faunt, Claudia C.; Phillips, Steven P.
2015-01-01
Coupled groundwater and surface-water components of the hydrologic cycle can be simulated by the Farm Process for MODFLOW (MF-FMP) in both irrigated and non-irrigated areas and aquifer-storage and recovery systems. MF-FMP is being applied to three productive agricultural regions of different scale in the State of California, USA, to assess the availability of water and the impacts of alternative management decisions. Hindcast simulations are conducted for similar periods from the 1960s to near recent times. Historical groundwater pumpage is mostly unknown in one region (Central Valley) and is estimated by MF-FMP. In another region (Pajaro Valley), recorded pumpage is used to calibrate model-estimated pumpage. Multiple types of observations are used to estimate uncertain parameters, such as hydraulic, land-use, and farm properties. MF-FMP simulates how climate variability and water-import availability affect water demand and supply. MF-FMP can be used to predict water availability based on anticipated changes in anthropogenic or natural water demands. Keywords groundwater; surface-water; irrigation; water availability; response to climate variability/change
Online professionalism: A synthetic review.
Chretien, Katherine C; Tuck, Matthew G
2015-04-01
The rise of social media has increased connectivity and blurred personal and professional boundaries, bringing new challenges for medical professionalism. Whether traditional professionalism principles apply to the online social media space remains unknown. The purpose of this synthetic literature review was to characterize the original peer-reviewed research studies published between 1 January 2000-1 November 2014 on online professionalism, to assess methodologies and approaches used, and to provide insights to guide future studies in this area. The investigators searched three databases and performed manual searches of bibliographies to identify the 32 studies included. Most studies originated in the USA. Cross-sectional surveys and analyses of publicly available online content were the most common methodologies employed. Studies covered the general areas of use and privacy, assessment of unprofessional online behaviours, consensus-gathering of what constitutes unprofessional or inappropriate online behaviours, and education and policies. Studies were of variable quality; only around half of survey studies had response rates of 50% or greater. Medical trainees were the most common population studied. Future directions for research include public perspectives of online professionalism, impact on patient trust, and how to use social media productively as medical professionals.
The criminal purchase of firearm ammunition
Tita, G E; Braga, A A; Ridgeway, G; Pierce, G L
2006-01-01
Objective Laws that prohibit certain individuals from owning firearms also pertain to ammunition. Whereas retail sales of firearms to criminals are regularly disrupted by instant background checks, sales of ammunition are essentially unchecked and the rate at which criminals acquire ammunition is unknown. This research describes the ammunition market and estimates the rate at which criminals are acquiring ammunition. Design Criminal background checks conducted on individuals purchasing ammunition in the City of Los Angeles in April and May 2004. Setting Los Angeles, CA, USA. Subjects Ammunition purchasers. Main outcome measures Criminal activity that prohibits one from owning, purchasing, or possessing ammunition. Results 2.6% (95% CI 1.9% to 3.2%) of ammunition purchasers had a prior felony conviction or another condition that prohibited them from possessing ammunition. During the study period prohibited possessors purchased 10 050 rounds of ammunition in Los Angeles. Conclusions These estimates suggest that monitoring ammunition transactions may help reduce the supply of ammunition to criminals and the frequency of injuries from felonious gun assaults. Such a record can also provide information for generating leads on illegal firearm possession. PMID:17018671
78 FR 64020 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried USA, LLC
Federal Register 2010, 2011, 2012, 2013, 2014
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...; Notice of Registration; Siegfried USA, LLC By Notice dated May 22, 2013, and published in the Federal Register on May 30, 2013, 78 FR 32458, Siegfried USA, LLC., 33 Industrial Park Road, Pennsville, New Jersey... determined that the registration of Siegfried USA, LLC., to manufacture the listed basic class of controlled...
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Age at onset in bipolar I affective disorder in the USA and Europe.
Bellivier, Frank; Etain, Bruno; Malafosse, Alain; Henry, Chantal; Kahn, Jean-Pierre; Elgrabli-Wajsbrot, Orly; Jamain, Stéphane; Azorin, Jean-Michel; Frank, Ellen; Scott, Jan; Grochocinski, Victoria; Kupfer, David J; Golmard, Jean-Louis; Leboyer, Marion
2014-07-01
To test for differences in reported age at onset (AAO) of bipolar I affective disorder in clinical samples drawn from Europe and the USA. Admixture analysis was used to identify the model best fitting the observed AAO distributions of two large samples of bipolar I patients from Europe and USA (n = 3616 and n = 2275, respectively). Theoretical AAO functions were compared between the two samples. The model best fitting the observed distribution of AAO in both samples was a mixture of three Gaussian distributions. The theoretical AAO functions of bipolar I disorder differed significantly between the European and USA populations, with further analyses indicating that (i) the proportion of patients belonging to the early-onset subgroup was higher in the USA sample (63 vs. 25%) and (ii) mean age at onset (±SD) in the early-onset subgroup was lower for the USA sample (14.5 ± 4.9 vs. 19 ± 2.7 years). The models best describing the reported AAO distributions of European and USA bipolar I patients were remarkably stable. The intermediate- and late-onset subgroups had similar characteristics in the two samples. However, the theoretical AAO function differed significantly between the USA and European samples due to the higher proportion of patients in the early-onset subgroup and the lower mean age-at-onset in the USA sample.
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Homeschooling as an Alternative Form of Educational Provision in South Africa and the USA
ERIC Educational Resources Information Center
de Waal, Esther; Theron, Tinie
2003-01-01
This paper studies homeschooling as an alternative form of educational provision in South Africa and USA to determine what knowledge and experiences from research on homeschooling in the USA may be relevant to the South Africa situation. Homeschooling in the USA has a sound legal foundation and has become an acceptable educational alternative.…
2003-12-19
KENNEDY SPACE CENTER, FLA. -- From left, United Space Alliance (USA) Deputy Space Shuttle Program Manager of Operations Loren Shriver, USA Associate Program Manager of Ground Operations Andy Allen, NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik, and USA Vice President and Space Shuttle Program Manager Howard DeCastro examine a tile used in the Shuttle's Thermal Protection System (TPS) in KSC's TPS Facility. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.
PREFACE Turbulent Mixing and Beyond
NASA Astrophysics Data System (ADS)
Abarzhi, Snezhana I.; Gauthier, Serge; Niemela, Joseph J.
2010-12-01
The goals of the International Conference 'Turbulent Mixing and Beyond', TMB-2009, are to expose the generic problem of non-equilibrium turbulent processes to a broad scientific community, to promote the development of new ideas in tackling the fundamental aspects of the problem, to assist in the application of novel approaches in a broad range of phenomena, where the turbulent processes occur, and to have a potential impact on technology. The Conference provides the opportunity to bring together researchers from different areas, which include but are not limited to fluid dynamics, plasmas, high energy density physics, astrophysics, material science, combustion, atmospheric and Earth sciences, nonlinear and statistical physics, applied mathematics, probability and statistics, data processing and computations, optics and telecommunications, and to have their attention focused on the long-standing formidable task of non-equilibrium processes. Non-equilibrium turbulent processes play a key role in a broad variety of phenomena spanning astrophysical to atomistic scales and high or low energy density regimes. Inertial confinement and magnetic fusion, light-matter interaction and non-equilibrium heat transfer, strong shocks and explosions, material transformation under high strain rate, supernovae and accretion disks, stellar non-Boussinesq and magneto-convection, planetary interiors and mantle-lithosphere tectonics, premixed and non-premixed combustion, non-canonical wall-bounded flows, hypersonic and supersonic boundary layers, dynamics of atmosphere and oceanography, are just a few examples. A grip on non-equilibrium turbulent processes is crucial for cutting-edge technology such as laser micro-machining, nano-electronics, free-space optical telecommunications, and for industrial applications in the areas of aeronautics and aerodynamics. Non-equilibrium turbulent processes are anisotropic, non-local, multi-scale and multi-phase, and often are driven by shocks or acceleration. Their scaling, spectral and invariant properties differ substantially from those of classical Kolmogorov turbulence. At atomistic and meso-scales, the non-equilibrium dynamics depart dramatically from a standard scenario given by the Gibbs statistic ensemble average and quasi-static Boltzmann equation. The singular aspect and the similarity of the non-equilibrium dynamics at macroscopic scales are interplayed with the fundamental properties of the Euler and compressible Navier-Stokes equations and with the problem sensitivity to the boundary conditions at discontinuities. The state-of-the-art numerical simulations of multi-phase flows suggest new methods for predictive modeling of the multi-scale non-equilibrium dynamics in fluids and plasmas, up to peta-scale level, for error estimate and uncertainty quantification, as well as for novel data assimilation techniques. The Second International Conference and Advanced School 'Turbulent Mixing and Beyond', TMB-2009, was held on 27 July-7 August 2009 at the Abdus Salam International Centre for Theoretical Physics (ICTP), Trieste, Italy. This was a highly informative and exciting meeting, and it strengthened and reaffirmed the success of TMB-2007. TMB-2009 brought together over 180 participants from five continents, ranging from students to members of National Academies of Sciences and Engineering and including researchers at experienced and early stages of their carriers from leading scientific institutions in academia, national laboratories, corporations and industry, from developed and developing countries. The success of TMB-2009 came from the successful work of all the participants, who were responsible professionals caring for the quality of their research and sharing their scientific vision. The level of presentations was high; about 170 presentations included over 60 invited lectures and 15 tutorials (4500 minutes of talks in total), about 40 posters and two Round Tables. TMB-2009 covered 17 different topics, maintaining the scope and the interdisciplinary character of the meeting while keeping the focus on a fundamental scientific problem of non-equilibrium processes and on the Conference objectives. The abstracts of the 194 accepted presentations of more than 400 authors were published in the Book of Abstracts of the Second International Conference and Advanced School 'Turbulent Mixing and Beyond', 27 July-7 August 2009 , Copyright © 2009, the Abdus Salam International Centre for Theoretical Physics, Trieste, Italy (ISBN 92095003-41-1). This Topical Issue consists of 70 articles accepted for publication in the Conference Proceedings and represents a substantial part of the Conference contributions. The articles are in a broad variety of TMB-2009 themes and are sorted alphabetically by the last name of the first author within each of the following topics: Canonical turbulence and turbulent mixing: invariant, scaling, spectral properties, scalar transports, convection; Wall-bounded flows: structure and fundamentals, non-canonical turbulent boundary layers, including unsteady and transitional flows, supersonic and hypersonic flows, shock-boundary layer interactions; Non-equilibrium processes: unsteady, multiphase and shock-driven turbulent flows, anisotropic non-local dynamics, connection of continuous description at macro-scales to kinetic processes at atomistic scales; Interfacial dynamics: instabilities of Rayleigh-Taylor, Kelvin-Helmholtz, Richtmyer-Meshkov, Landau-Darrieus, Saffman-Taylor High energy density physics: inertial confinement and heavy-ion fusion, Z-pinches, light-matter and laser-plasma interactions, non-equilibrium heat transfer; Material science: material transformation under high strain rates, equation of state, impact dynamics, mixing at nano- and micro-scales; Astrophysics: supernovae, interstellar medium, star formation, stellar interiors, early Universe, cosmic-microwave background, accretion disks; Magneto-hydrodynamics: magnetic fusion and magnetically confined plasmas, magneto-convection, magneto-rotational instability, dynamo; Canonical plasmas: coupled plasmas, anomalous resistance, ionosphere; Physics of atmosphere: environmental fluid dynamics, weather forecasting, turbulent flows in stratified media and atmosphere, non-Boussinesq convection; Geophysics and Earth science: mantle-lithosphere tectonics, oceanography, turbulent convection under rotation, planetary interiors; Combustion: dynamics of flames and fires, deflagration-to-detonation transition, blast waves and explosions, flows with chemical reactions, flows in jet engines; Mathematical aspects of non-equilibrium dynamics: vortex dynamics, singularities, discontinuities, asymptotic dynamics, weak solutions, well- and ill-posedness, continuous transports out of thermodynamic equilibrium; Stochastic processes and probabilistic description: long-tail distributions and anomalous diffusion, data assimilation and processing methodologies, error estimate and uncertainty quantification, statistically unsteady processes; Advanced numerical simulations: continuous DNS/LES/RANS, molecular dynamics, Monte-Carlo, predictive modeling, validation and verification of numerical models; Experimental diagnostics: model experiments in high energy density and low energy density regimes, plasma diagnostics, fluid flow visualizations and control, opto-fluidics, novel optical methods, holography, advanced technologies. TMB-2009 was organized by the following members of the Organizing Committee: Snezhana I Abarzhi (chairperson, Chicago, USA) Malcolm J Andrews (Los Alamos National Laboratory, USA) Sergei I Anisimov (Landau Institute for Theoretical Physics, Russia) Hiroshi Azechi (Institute of Laser Engineering, Osaka, Japan) Serge Gauthier (Commissariat à l'Energie Atomique, France) Christopher J Keane (Lawrence Livermore National Laboratory, USA) Robert Rosner (Argonne National Laboratory, USA) Katepalli R Sreenivasan (International Centre for Theoretical Physics, Italy) Alexander L Velikovich (Naval Research Laboratory, USA) and the Local Organizing Committee at the International Centre for Theoretical Physics, Italy Joseph J Niemela Katepalli R Sreenivasan with the assistance of Suzie Radosic (administrator and assistant, ICTP) Daniil Ilyin (web-master, University of Chicago Laboratory Schools, Chicago, USA) The Conference and the School were sponsored by several Agencies and Institutions in the USA, Europe and Japan. The Organizing Committee of TMB-2009 gratefully acknowledges the support of International Centre for Theoretical Physics (ICTP), Italy National Science Foundation (NSF), USA Programs: Plasma Physics; Astronomy and Astrophysics; Computational Mathematics; Applied Mathematics; Fluid Dynamics; Combustion, Fire and Plasma Systems; Cyber-Physical Systems; Computer and Network Systems Air Force Office of Scientific Research (AFOSR), US Programs: Hypersonics and Turbulence; Flow Control and Aeroelasticity European Office of Aerospace Research and Development (EOARD) of the AFOSR, UK Programs: Aeronautical Sciences Department of Energy (DOE), USA, DOE Office of Science US Department of Energy Lawrence Livermore National Laboratory (LLNL), USA Programs: National Ignition Facility; Fusion Energy US Department of Energy Los Alamos National Laboratory (LANL), USA US Department of Energy Argonne National Laboratory (ANL), USA Commissariat à l'Energie Atomique (CEA), France Institute for Laser Engineering (ILE), Japan The University of Chicago, USA ASC Alliance Center for Astrophysical Thermonuclear Flashes, USA Photron (Europe) Ltd, UK and thank them for making this event possible. We express our gratitude for the help with the Conference Program to the members of the Scientific Advisory Committee: S I Abarzhi (University of Chicago, USA) Y Aglitskiy (Science Applications International Corporation, USA) H Azechi (Institute for Laser Engineering, Osaka, Japan) M J Andrews (Los Alamos National Laboratory, USA) S I Anisimov (Landau Institute for Theoretical Physics, Russia) E Bodenschatz (Max Plank Institute for Dynamics and Self-Organization, Germany) F Cattaneo (University of Chicago, USA) P Cvitanović (Georgia Institute of Technology, USA) S Cowley (Imperial College, UK) S Dalziel (DAMTP, University of Cambridge, UK) W S Don (Brown University, USA) R Ecke (Los Alamos National Laboratory, USA) H J Fernando (Arizona State University, USA) I Foster (University of Chicago, USA) S Gauthier (Commissariat à l'Energie Atomique, France) G A Glatzmaier (University of California at Santa Cruz, USA) J Glimm (State University of New York at Stony Brook, USA) W A Goddard III (California Institute of Technology, USA) J Jimenez (Universidad Politecnica de Madrid, Spain) L P Kadanoff (The University of Chicago, USA) D Q Lamb (The University of Chicago, USA) D P Lathrop (University of Maryland, USA) S Lebedev (Imperial College, UK) P Manneville (École Polytechnique, France) D I Meiron (California Institute of Technology, USA) P Moin (Stanford University, USA) A Nepomnyashchy (Technion, Israel) J Niemela (International Center for Theoretical Physics, Italy) K Nishihara (Institute for Laser Engineering, Osaka, Japan) S S Orlov (Stanford University, USA) S A Orszag (Yale University, USA) E Ott (University of Maryland, USA) N Peters (RWTH Aachen University, Germany) S B Pope (Cornell, USA) A Pouquet (University Corporation for Atmospheric Research, USA) B A Remington (Lawrence Livermore National Laboratory, USA) R Rosner (Argonne National Laboratory and University of Chicago, USA) A J Schmitt (Naval Research Laboratory, USA) C -W Shu (Brown University, USA) K R Sreenivasan (International Centre for Theoretical Physics, Italy) E Tadmor (University of Maryland, USA) Y C F Thio (US Department of Energy) A L Velikovich (Naval Research Laboratory, USA) V Yakhot (Boston University, USA) P K Yeung (Georgia Institute of Technology, USA) F A Williams (University of California at San Diego, USA) E Zweibel (University of Wisconsin, USA). We deeply appreciate the work of the Selection Committee for applications for the Advanced School: S Gauthier (Commissariat à l'Energie Atomique, France) C J Keane (Lawrence Livermore National Laboratory, USA) J Niemela (International Center for Theoretical Physics, Italy) S S Orlov (Stanford University, USA) A L Velikovich (Naval Research Laboratory, USA) and thank the members of the Committee for the award 'Turbulent Mixing and Beyond for Youth': S I Abarzhi (University of Chicago, USA) M J Andrews (Los Alamos National Laboratory, USA) P Cvitanović (Georgia Institute of Technology, USA) S Gauthier (Commissariat à l'Energie Atomique, France) C J Keane (Lawrence Livermore National Laboratory, USA) S Lebedev (Imperial College, UK) J Niemela (International Center for Theoretical Physics, Italy) S S Orlov (Stanford University, USA) A Pouquet (University Corporation for Atmospheric Research, USA) K R Sreenivasan (International Centre for Theoretical Physics, Italy) A L Velikovich (Naval Research Laboratory, USA) We would like to thank all the authors and the referees for their contributions to this Topical Issue and for offering their expertise, time and effort. The readers are cordially invited to take a look at this Topical Issue for information on the frontiers of theoretical, numerical and experimental research, and state-of-the-art technology. The Organizing Committee hopes the TMB Conference will serve to advance the state-of-the-art in understanding of fundamental physical properties of non-equilibrium turbulent processes and will have an impact on predictive modeling capabilities, physical description and, ultimately, control of these complex processes. Welcome to the Topical Issue 'Turbulent Mixing and Beyond', TMB-2009.
Arab American Parents' Perceptions of Their Children's Experience in the USA: A Qualitative Study
ERIC Educational Resources Information Center
Ahmad, Jamal
2017-01-01
The purpose of this study was to examine Arab American parents' perceptions of difficulties their children experience in the USA. Both Arab American children born outside the USA who later moved to the country and children born in the USA to Arab parents were examined. Fifty Arab American families were interviewed in two areas in the State of…
Interferometry of Epsilon Aurigae: Characterization of the Asymmetric Eclipsing Disk
2015-09-21
Observatory, Mount Wilson, California 91023, USA; bkloppenborg@chara.gsu.edu 2 Department of Physics & Astronomy, University of Denver, Denver, CO...80208 USA 3 Department of Astronomy, University of Michigan, 941 Dennison Building, Ann Arbor, Michigan 48109, USA 4 Department of Physics , Central...Observatory Road, Flagstaff, Arizona 86001, USA 6 Department of Physics and Astronomy, Penn. State, University Park, PA 16802 7 School of Engineering
US GODAE: Global Ocean Prediction with the Hybrid Coordinate Ocean Model (HYCOM)
2009-06-01
Administration, New York, NY, USA, and Earth Systems Research Laboratory, NOAA, Boulder, CO, USA. Remy Baraille is Research Scientist, Service Hydrographique...Coastal Sciences, Rutgers University, New Brunswick, NJ, USA. John Wilkin is Associate Professor, Institute of Marine and Coastal Sciences, Rutgers...University, New Brunswick, NJ, USA. Oceanography June 2009 67 coordinates (depth, density, and terrain- following) provide universal optimality, it is
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2013-08-06
....V. and Coach USA AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of... exemption from Van Hool N.V. and Coach USA (Van Hool/Coach USA) to allow the use of double deck motorcoaches..., Van Hool/Coach USA is requesting an exemption that would allow the use of sleeper berths that comply...
Langer, Robert
2012-10-01
Professor Robert Langer obtained his Bachelor's Degree in Chemical Engineering from Cornell University (NY, USA) in 1970. He received his Sc.D. from the Massachusetts Institute of Technology (MA, USA) in 1974. He is currently the David H Koch Institute Professor at the Massachusetts Institute of Technology. Professor Langer is a member of the Institute of Medicine of the National Academy of Sciences, the National Academy of Engineering and the National Academy of Sciences. At the age of 43 he was the youngest person in history to be elected to all three United States National Academies. Throughout his career, Professor Langer has received over 200 awards including, notably, the Charles Stark Draper Prize (considered the equivalent of the Nobel Prize for engineers), the 2008 Millennium Prize, the 2006 United States National Medal of Science and the 2012 Priestley Medal. In 1996 he was awarded the Gairdner Foundation International Award (the only engineer ever to have been awarded this accolade). Professor Langer has also been the recipient of the Lemelson-MIT prize, which he was awarded with for being "one of history's most prolific inventors in medicine." Professor Langer was selected by Time Magazine in 2001 as one of the 100 most important people in the USA. He has received honorary degrees from several universities worldwide, including Harvard University (MA, USA), the Mt. Sinai School of Medicine (NY, USA), Yale University (CT, USA), the ETH Zurich (Zurich, Switzerland), the Technion-Israel Institute of Technology (Haifa, Israel), the Hebrew University of Jerusalem (Israel), the Université Catholique de Louvain (Louvain-La-Neuve, Belgium), Rensselaer Polytechnic Institute (NY, USA), Willamette University (OR, USA), the University of Liverpool (Liverpool, UK), Bates College (ME, USA), the University of Nottingham (Nottingham, UK), Albany Medical College (NY, USA), Pennsylvania State University (PA, USA), Northwestern University (IL, USA) and Uppsala University (Uppsala, Sweden), and was awarded with the University of California San Francisco Medal in 2009. Professor Langer has founded over 20 biotechnology companies and authored more than 1175 articles. He has over 800 issued or pending patents. Professor Langer is the most cited engineer in history.
Joffres, Michel; Falaschetti, Emanuela; Gillespie, Cathleen; Robitaille, Cynthia; Loustalot, Fleetwood; Poulter, Neil; McAlister, Finlay A; Johansen, Helen; Baclic, Oliver; Campbell, Norm
2013-08-30
Comparison of recent national survey data on prevalence, awareness, treatment and control of hypertension in England, the USA and Canada, and correlation of these parameters with each country stroke and ischaemic heart disease (IHD) mortality. Non-institutionalised population surveys. England (2006 n=6873), the USA (2007-2010 n=10 003) and Canada (2007-2009 n=3485) aged 20-79 years. Stroke and IHD mortality rates were plotted against countries' specific prevalence data. Mean systolic blood pressure (SBP) was higher in England than in the USA and Canada in all age-gender groups. Mean diastolic blood pressure (DBP) was similar in the three countries before age 50 and then fell more rapidly in the USA, being the lowest in the USA. Only 34% had a BP under 140/90 mm Hg in England, compared with 50% in the USA and 66% in Canada. Prehypertension and stages 1 and 2 hypertension prevalence figures were the highest in England. Hypertension prevalence (≥140 mm Hg SBP and/or ≥90 mm Hg DBP) was lower in Canada (19·5%) than in the USA (29%) and England (30%). Hypertension awareness was higher in the USA (81%) and Canada (83%) than in England (65%). England also had lower levels of hypertension treatment (51%; USA 74%; Canada 80%) and control (<140/90 mm Hg; 27%; the USA 53%; Canada 66%). Canada had the lowest stroke and IHD mortality rates, England the highest and the rates were inversely related to the mean SBP in each country and strongly related to the blood pressure indicators, the strongest relationship being between low hypertension awareness and stroke mortality. While the current prevention efforts in England should result in future-improved figures, especially at younger ages, these data still show important gaps in the management of hypertension in these countries, with consequences on stroke and IHD mortality.
Testing of the International Space Station and X-38 Crew Return Vehicle GPS Receiver
NASA Technical Reports Server (NTRS)
Simpson, James; Campbell, Chip; Carpenter, Russell; Davis, Ed; Kizhner, Semion; Lightsey, E. Glenn; Davis, George; Jackson, Larry
1999-01-01
This paper discusses the process and results of the performance testing of the GPS receiver planned for use on the International Space Station (ISS) and the X-38 Crew Return Vehicle (CRV). The receiver is a Force-19 unit manufactured by Trimble Navigation and modified in software by the NASA Goddard Space Flight Center (GSFC) to perform navigation and attitude determination in space. The receiver is the primary source of navigation and attitude information for ISS and CRV. Engineers at GSFC have developed and tested the new receiver with a Global Simulation Systems Ltd (GSS) GPS Signal Generator (GPSSG). This paper documents the unique aspects of ground testing a GPS receiver that is designed for use in space. A discussion of the design of tests using the GPSSG, documentation, data capture, data analysis, and lessons learned will precede an overview of the performance of the new receiver. A description of the challenges that were overcome during this testing exercise will be presented. Results from testing show that the receiver will be within or near the specifications for ISS attitude and navigation performance. The process for verifying other requirements such as Time to First Fix, Time to First Attitude, selection/deselection of a specific GPS satellite vehicles (SV), minimum signal strength while still obtaining attitude and navigation, navigation and attitude output coverage, GPS week rollover, and Y2K requirements are also given in this paper.
Testing of the International Space Station and X-38 Crew Return Vehicle GPS Receiver
NASA Technical Reports Server (NTRS)
Simpson, James; Campbell, Chip; Carpenter, Russell; Davis, Ed; Kizhner, Semion; Lightsey, E. Glenn; Davis, George; Jackson, Larry
1999-01-01
This paper discusses the process and results of the performance testing of the GPS receiver planned for use on the International Space Station (ISS) and the X-38 Crew Return Vehicle (CRV). The receiver is a Force-19 unit manufactured by Trimble Navigation and Modified in software by the NASA Goddard Space Flight Center (GSFC) to perform navigation and attitude determination in space. The receiver is the primary source of navigation and attitude information for ISS and CRV. Engineers at GSFC have developed and tested the new receiver with a Global Simulation Systems Ltd (GSS) GPS Signal Generator (GPSSG). This paper documents the unique aspects of ground testing a GPS receiver that is designed for use in space. A discussion of the design and tests using the GPSSG, documentation, data capture, data analysis, and lessons learned will precede an overview of the performance of the new receiver. A description of the challenges of that were overcome during this testing exercise will be presented. Results from testing show that the receiver will be within or near the specifications for ISS attitude and navigation performance. The process for verifying other requirements such as Time to First Fix, Time to First Attitude, selection/deselection of a specific GPS satellite vehicles (SV), minimum signal strength while still obtaining attitude and navigation, navigation and attitude output coverage, GPS week rollover, and Y2K requirements are also given in this paper.
NASA Astrophysics Data System (ADS)
Salach, A.
2017-05-01
The documentary value of analogue scanned photographs is invaluable. A large and rich collection of archival photographs is often the only source of information about past of the selected area. This paper presents a method of adaptation of scanned, analogue photographs to suitable form allowing to use them in Structure from Motion technology. For this purpose, an automatic algorithm, implemented in the application called SAPC (Scanned Aerial Photographs Correction), which transforms scans to a form, which characteristic similar to the images captured by a digital camera, was invented. Images, which are created in the applied program as output data, are characterized by the same principal point position in each photo and the same resolution through cutting out the black photo frame. Additionally, SAPC generates a binary image file, which can mask areas of fiducial marks. In the experimental section, scanned, analogue photographs of Warsaw, which had been captured in 1986, were used in two variants: unprocessed and processed in SAPC application. An insightful analysis was conducted on the influence of transformation in SAPC on quality of spatial orientation of photographs. Block adjustment through aerial triangulation was calculated using two SfM software products: Agisoft PhotoScan and Pix4d and their results were compared with results obtained from professional photogrammetric software - Trimble Inpho. The author concluded that pre-processing in SAPC application had a positive impact on a quality of block orientation of scanned, analogue photographs, using SfM technology.
Wetland Assessment Using Unmanned Aerial Vehicle (uav) Photogrammetry
NASA Astrophysics Data System (ADS)
Boon, M. A.; Greenfield, R.; Tesfamichael, S.
2016-06-01
The use of Unmanned Arial Vehicle (UAV) photogrammetry is a valuable tool to enhance our understanding of wetlands. Accurate planning derived from this technological advancement allows for more effective management and conservation of wetland areas. This paper presents results of a study that aimed at investigating the use of UAV photogrammetry as a tool to enhance the assessment of wetland ecosystems. The UAV images were collected during a single flight within 2½ hours over a 100 ha area at the Kameelzynkraal farm, Gauteng Province, South Africa. An AKS Y-6 MKII multi-rotor UAV and a digital camera on a motion compensated gimbal mount were utilised for the survey. Twenty ground control points (GCPs) were surveyed using a Trimble GPS to achieve geometrical precision and georeferencing accuracy. Structure-from-Motion (SfM) computer vision techniques were used to derive ultra-high resolution point clouds, orthophotos and 3D models from the multi-view photos. The geometric accuracy of the data based on the 20 GCP's were 0.018 m for the overall, 0.0025 m for the vertical root mean squared error (RMSE) and an over all root mean square reprojection error of 0.18 pixel. The UAV products were then edited and subsequently analysed, interpreted and key attributes extracted using a selection of tools/ software applications to enhance the wetland assessment. The results exceeded our expectations and provided a valuable and accurate enhancement to the wetland delineation, classification and health assessment which even with detailed field studies would have been difficult to achieve.
Hepatobiliary Hands of Hopkins.
Pitt, Henry A
2018-02-01
This historical perspective documents the role that John L. Cameron played in advancing hepatobiliary research, education, and surgery at Johns Hopkins in the 1970s, 1980s, and 1990s. Dating back to William S. Halsted in the 19th century, leaders of the Department of Surgery at Johns Hopkins have been interested in hepatobiliary disease and surgery. John L. Cameron had broad hepato-pancreato-biliary (HPB) interests when he completed his surgical training. Over the next 3 decades, he focused on the pancreas. As a result, many faculty and trainee hepatobiliary careers were launched. This perspective is based on 18 years of service as a surgical resident and faculty member at Johns Hopkins. An extensive literature search on the hepatobiliary publications of Halsted, Trimble, Blalock, Longmire, Zuidema, and Cameron was undertaken for this manuscript. Numerous hepatobiliary publications from Johns Hopkins from the 1970s, 1980s, 1990s, and early 2000s were also reviewed. John L. Cameron's early biliary interests included stones, infections, malignancies, and strictures. He was innovative with respect to portal hypertension and Budd-Chiari surgery and supportive when liver transplantation emerged in the 1980s. Volume-outcome studies in the 1990s included hepatic and complex biliary surgery. He supported and encouraged studies of biliary lithotripsy, laparoscopic cholecystectomy, clinical pathways, hepatobiliary cysts, and gallstone pathogenesis. Lessons learned by many who worked with John L. Cameron included the importance of mentorship, innovation, friendship, and collaboration. He taught leadership and change management by example. He fostered a multidisciplinary approach and encouraged randomized controlled trials.
Testing of the International Space Station and X-38 Crew Return Vehicle GPS Receiver
NASA Technical Reports Server (NTRS)
Simpson, James; Lightsey, Glenn; Campbell, Chip; Carpenter, Russell; Davis, George; Jackson, Larry; Davis, Ed; Kizhner, Semion
1999-01-01
This paper discusses the process and results of the performance testing of the GPS receiver planned for use on the International Space Station (ISS) and the X- 38CrewReturnVehicle(CRV). The receiver is a Force-19 unit manufactured by Trimble Navigation and modified in software by NASA:s Goddard Space Flight Center (GSFC) to perform navigation and attitude determination in space. The receiver is the primary source of navigation and attitude information for ISS and CRV. Engineers at GSFC have developed and tested the new receiver with a Global Simulation Systems Ltd (GSS) GPS Signal Generator (GPSSG). This paper documents the unique aspects of ground testing a GPS receiver that is designed for use in space. A discussion of the design of tests using the GPSSG, documentation, data capture, data analysis, and lessons learned will precede an overview of the performance of the new receiver. A description of the challenges that were overcome during this testing exercise will be presented. Results from testing show that the receiver will be within or near the specifications for ISS attitude and navigation performance. The process for verifying other requirements such as Time to First Fix, Time to First Attitude, selection/deselection of a specific GPS satellite vehicles (SV), minimum signal strength while still obtaining attitude and navigation, navigation and attitude output coverage, GPS week rollover, and Y2K requirements are also given in this paper.
Sachdeva, Ashwin; van der Meulen, Jan H; Emberton, Mark; Cathcart, Paul J
2015-02-24
Prostate cancer mortality (PCM) in the USA is among the lowest in the world, whereas PCM in England is among the highest in Europe. This paper aims to assess the association of variation in use of definitive therapy on risk-adjusted PCM in England as compared with the USA. Observational study. Cancer registry data from England and the USA. Men diagnosed with non-metastatic prostate cancer (PCa) in England and the USA between 2004 and 2008. Competing-risks survival analyses to estimate subhazard ratios (SHR) of PCM adjusted for age, ethnicity, year of diagnosis, Gleason score (GS) and clinical tumour (cT) stage. 222,163 men were eligible for inclusion. Compared with American patients, English patients were more likely to present at an older age (70-79 years: England 44.2%, USA 29.3%, p<0.001), with higher tumour stage (cT3-T4: England 25.1%, USA 8.6%, p<0.001) and higher GS (GS 8-10: England 20.7%, USA 11.2%, p<0.001). They were also less likely to receive definitive therapy (England 38%, USA 77%, p<0.001). English patients were more likely to die of PCa (SHR=1.9, 95% CI 1.7 to 2.0, p<0.001). However, this difference was no longer statistically significant when also adjusted for use of definitive therapy (SHR=1.0, 95% CI 1.0 to 1.1, p=0.3). Risk-adjusted PCM is significantly higher in England compared with the USA. This difference may be explained by less frequent use of definitive therapy in England. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
75 FR 65317 - Combined Notice of Filings #1
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-22
..., 2010. Docket Numbers: ER11-85-000. Applicants: Societe Generale Energie (USA) Corp. Description: Societe Generale Energie (USA) Corp. submits tariff filing per 35.12: SGE USA Baseline Tariff Filing to be...
USA National Phenology Network gridded products documentation
Crimmins, Theresa M.; Marsh, R. Lee; Switzer, Jeff R.; Crimmins, Michael A.; Gerst, Katharine L.; Rosemartin, Alyssa H.; Weltzin, Jake F.
2017-02-23
The goals of the USA National Phenology Network (USA-NPN, www.usanpn.org) are to advance science, inform decisions, and communicate and connect with the public regarding phenology and species’ responses to environmental variation and climate change. The USA-NPN seeks to facilitate informed ecosystem stewardship and management by providing phenological information freely and openly. One way the USA-NPN is endeavoring to accomplish these goals is by providing data and data products in a wide range of formats, including gridded real-time, short-term forecasted, and historical maps of phenological events, patterns and trends. This document describes the suite of gridded phenologically relevant data products produced and provided by the USA National Phenology Network, which can be accessed at www.usanpn.org/data/phenology_maps and also through web services at geoserver.usanpn.org/geoserver/wms?request=GetCapabilities.
Lewis, Drew D; Johnson, Mary T; Finnerty, Edward P
2014-06-01
Osteopathic manual medicine (OMM) encompasses hands-on diagnosis and treatment as part of patient care. The area of osteopathic principles and practice (OPP) is considered a core competency for students and practitioners of this medical tradition. The Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) is a useful tool for assessing candidates' competency. To examine the relationship of COMLEX-USA Level 1 total scores and OPP subscores with OMM course grades, and to determine if these grades are predictive of COMLEX-USA Level 1 OPP performance. The authors collected data-COMLEX-USA Level 1 total and OPP subscores, OMM grades (written, practical, and total for first and second academic years), sex, and age-for a cohort of osteopathic medical students at a single institution, and these data were then analyzed by means of correlation analysis. Records were obtained from a second-year class of osteopathic medical students (N=217). The authors' analysis of total scores and OPP subscores on COMLEX-USA Level 1 yielded a statistically significant correlation with all variables. Although the correlations were moderate, second-year written examination grades showed the strongest association with the COMLEX-USA Level 1 OPP subscores (r=0.530) and total scores (r=0.566). Performance in the second-year OMM written examination could identify students potentially at risk for poor performance on COMLEX-USA Level 1. © 2014 The American Osteopathic Association.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-20
... and Order Granting a Waiver to LG Electronics U.S.A., Inc. From the Department of Energy Commercial.... Department of Energy's (DOE) Decision and Order in Case No. CAC-036, which grants LG Electronics U.S.A., Inc.... Decision and Order In the Matter of: LG Electronics U.S.A., Inc. (LG) (Case No. CAC- 036). Background Title...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-08
..., [Unnamed] Drosophila aglaia...... E U.S.A. (HI) 71 FR 26835; 5/9/2006. Pomace fly, [Unnamed] Drosophila differens... E U.S.A. (HI) 71 FR 26835; 5/9/2006. Pomace fly, [Unnamed] Drosophila hemipeza.... E U.S.A. (HI) 71 FR 26835; 5/9/2006. Pomace fly, [Unnamed] Drosophila heteroneura. E U.S.A. (HI) 71 FR 26835; 5/9...
2012-04-20
Observational Cosmology , NASA Goddard Space Flight Center, Code 665, Greenbelt, MD 20771, USA 31 Enrico Fermi Institute, Department of Physics, and Kavli...Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637, USA 32 Department of Physics and Astronomy, Rutgers, the State University...Austin, TX 78712, USA 59 Pittsburgh Particle Physics, Astrophysics, and Cosmology Center (Pitt-PACC), University of Pittsburgh, Pittsburgh, PA 15260, USA
Methods for Functional Connectivity Analyses
2012-12-13
motor , or hand motor function (green, red, or blue shading, respectively). Thus, this work produced the first comprehensive analysis of ECoG...Computer Engineering, University of Texas at El Paso , TX, USA 3Department of Neurology, Albany Medical College, Albany, NY, USA 4Department of Computer...Department of Health, Albany, NY, USA bDepartment of Electrical and Computer Engineering, University of Texas at El Paso , TX, USA cDepartment of Neurology
PREFACE: XXXVI Symposium on Nuclear Physics (Cocoyoc 2013)
NASA Astrophysics Data System (ADS)
Barrón-Palos, Libertad; Morales-Agiss, Irving; Martínez-Quiroz, Enrique
2014-03-01
logo The XXXVI Symposium on Nuclear Physics, organized by the Division of Nuclear Physics of the Mexican Physical Society, took place from 7-10 January, 2013. As it is customary, the Symposium was held at the Hotel Hacienda Cocoyoc, in the state of Morelos, Mexico. Conference photograph This international venue with many years of tradition was attended by outstanding physicists, some of them already regulars to this meeting and others who joined us for the first time; a total of 45 attendees from different countries (Argentina, Brazil, Canada, China, Germany, Italy, Japan, Mexico and the United States). A variety of topics related to nuclear physics (nuclear reactions, radioactive beams, nuclear structure, fundamental neutron physics, sub-nuclear physics and nuclear astrophysics, among others) were presented in 26 invited talks and 10 contributed posters. Local Organizing Committee Libertad Barrón-Palos (IF-UNAM)) Enrique Martínez-Quíroz (ININ)) Irving Morales-Agiss (ICN-UNAM)) International Advisory Committee Osvaldo Civitarese (UNLP, Argentina) Jerry P Draayer (LSU, USA)) Alfredo Galindo-Uribarri (ORNL, USA)) Paulo Gomes (UFF, Brazil)) Piet Van Isacker (GANIL, France)) James J Kolata (UND, USA)) Reiner Krücken (TRIUMF, Canada)) Jorge López (UTEP, USA)) Stuart Pittel (UD, USA)) W Michael Snow (IU, USA)) Adam Szczepaniak (IU, USA)) Michael Wiescher (UND, USA)) A list of participants is available in the PDF
National assessment of Tree City USA participation
Tree City USA is a national program that recognizes municipal commitment to community forestry. In return for meeting program requirements, Tree City USA participants expect social, economic, and/or environmental benefits. Understanding the geographic distribution and socioeconomic characteristics of Tree City USA communities at the national scale can offer insights into the motivations or barriers to program participation, and provide context for community forestry research at finer scales. In this study, researchers assessed patterns in Tree City USA participation for all U.S. communities with more than 2,500 people according to geography, community population size, and socioeconomic characteristics, such as income, education, and race. Nationally, 23.5% of communities studied were Tree City USA participants, and this accounted for 53.9% of the total population in these communities. Tree City USA participation rates varied substantially by U.S. region, but in each region participation rates were higher in larger communities, and long-term participants tended to be larger communities than more recent enrollees. In logistic regression models, owner occupancy rates were significant negative predictors of Tree City USA participation, education and percent white population were positive predictors in many U.S. regions, and inconsistent patterns were observed for income and population age. The findings indicate that communities with smaller populations, lower educat
Precipitation Records-HDSC/OWP
resources and services. Greatest observed point precipitation values for the world and the USA US Comparison of the greatest point precipitation values for the world and the USA. World records (map, table) USA
NASA Astrophysics Data System (ADS)
McComas, D. J.
2009-12-01
The Sun moves through the local interstellar medium, continuously emitting ionized, supersonic solar wind plasma and carving out a cavity in interstellar space, called the heliosphere. The Interstellar Boundary Explorer (IBEX) spacecraft has just completed the first all-sky maps of the interstellar interaction at the edge of the heliosphere, by imaging energetic neutral atoms (ENAs) emanating from this region. IBEX all-sky maps and energy spectra provide detailed information about the interaction. Our observations show globally distributed fluxes ordered by the solar wind structure, which are superposed by another, unexpected feature, which is neither seen by the Voyager spacecraft nor predicted by any current model or theory. This talk summarizes the IBEX observations, shares our unexpected results, and discusses some of the possible ideas for what may be missing in our current understanding of the heliosphere’s global interaction. IBEX Science Team: D.J. McComas1,2, F. Allegrini1,2, P. Bochsler3, M. Bzowski4, E.R. Christian5, G.B. Crew6, R. DeMajistre7, H. Fahr8, H. Fichtner9, P.C. Frisch10, H.O. Funsten11, S. A. Fuselier12, G. Gloeckler13, M. Gruntman14, J. Heerikhuisen15, V. Izmodenov16, P. Janzen17, P. Knappenberger18, S. Krimigis7,19, H. Kucharek20, M. Lee20, G. Livadiotis1, S. Livi1,2, R.J. MacDowall5, D. Mitchell7, E. Möbius20, T. Moore5, N.V. Pogorelov15, D. Reisenfeld17, E. Roelof7, L. Saul3, N.A. Schwadron21, P.W. Valek1,2, R. Vanderspek6, P. Wurz3, G.P. Zank15 (1)Southwest Research Institute, San Antonio, TX, USA (2) University of Texas at San Antonio, San Antonio, TX, USA (3)University of Bern, Physikalisches Institut, CH-3012 Bern, Switzerland (4)Space Research Centre of the Polish Academy of Sciences, Warsaw, Poland (5)NASA Goddard Space Flight Center, Greenbelt, MD, USA (6)Massachusetts Institute of Technology, Cambridge, MA, USA (7)Applied Physics Laboratory, Johns Hopkins University, Laurel, MD, USA (8)University of Bonn, Bonn, Germany (9)Ruhr-Universitaet Bochum, Bochum, Germany (10)University of Chicago, Chicago, IL, USA (11)Los Alamos National Laboratory, Los Alamos, NM, USA (12)Lockheed Martin Advanced Technology Center, Palo Alto, CA, USA (13)University of Michigan, Ann Arbor, MI, USA (14)University of Southern California, Los Angeles, CA, USA (15)University of Alabama, Huntsville, AL, USA (16) Moscow State University; Space Research Institute (IKI) and Institute for Problems in Mechanics Russian Academy of Sciences, Moscow, Russia (17)University of Montana, Missoula, MT, USA (18)Adler Planetarium, Chicago, IL, USA (19)Office for Space Research and Technology, Academy of Athens, Athens, Greece (20)University of New Hampshire, Space Science Center, Durham, NH, USA (21) Boston University, Boston, MA, USA
Defining Translational Reprogramming in Tuberous Sclerosis Complex
2015-07-01
Genomics & Development, Cornell University, Ithaca, New York, USA. 3Department of Chemistry, The Scripps Research Inst tute, Jupiter , Florida, USA...4Molecular Therapeutics and Natural Products Library Initiative, The Scripps Research Institute, Jupiter , Florida, USA. 5Present address
American Military History and its Insights into Fourth Generation Warfare
2006-01-01
8William S . Lind, Colonel Keith Nightengale (USA), Captain John F. Schmitt (USMC), Colonel Joseph W. Sutton (USA), and Lieutenant Colonel Gary I. Wilson...Lind, William S ., Colonel Keith Nightengale (USA), Captain John F. Schmitt (USMC), Colonel Joseph W. Sutton (USA), and Lieutenant Colonel Gary I...military history and its insights into fourth generation warfare. 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S
Dhatariya, Ketan K; Vellanki, Priyathama
2017-05-01
Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are diabetic emergencies that cause high morbidity and mortality. Their treatment differs in the UK and USA. This review delineates the differences in diagnosis and treatment between the two countries. Large-scale studies to determine optimal management of DKA and HHS are lacking. The diagnosis of DKA is based on disease severity in the USA, which differs from the UK. The diagnosis of HHS in the USA is based on total rather than effective osmolality. Unlike the USA, the UK has separate guidelines for DKA and HHS. Treatment of DKA and HHS also differs with respect to timing of fluid and insulin initiation. There is considerable overlap but important differences between the UK and USA guidelines for the management of DKA and HHS. Further research needs to be done to delineate a unifying diagnostic and treatment protocol.
Hager, B; Kraywinkel, K; Keck, B; Katalinic, A; Meyer, M; Zeissig, S R; Scheufele, R; Wirth, M P; Huber, J
2017-03-01
Current guidelines do not recommend a preferred treatment modality for locally advanced prostate cancer. The aim of the study was to compare treatment patterns found in the USA and Germany and to analyze possible trends over time. We compared 'Surveillance Epidemiology and End Results' (SEER) data (USA) with reports from four German federal epidemiological cancer registries (Eastern Germany, Bavaria, Rhineland-Palatinate, Schleswig-Holstein), both from 2004 to 2012. We defined locally advanced prostate cancer as clinical stage T3 or T4. Exclusion criteria were metastatic disease and age over 79 years. We identified 9127 (USA) and 11 051 (Germany) patients with locally advanced prostate cancer. The share was 2.1% in the USA compared with 6.0% in Germany (P<0.001). In the United States, the utilization of radiotherapy (RT) and radical prostatectomy (RP) was comparably high with 42.0% (RT) and 42.8% (RP). In Germany, the major treatment option was RP with 36.7% followed by RT with 22.1%. During the study period, the use of RP increased in both countries (USA P=0.001 and Germany P=0.003), whereas RT numbers declined (USA P=0.003 and Germany P=0.002). The share of adjuvant RT (aRT) was similar in both countries (USA 21.7% vs Germany 20.7%). We found distinctive differences in treating locally advanced prostate cancer between USA and Germany, but similar trends over time. In the last decade, a growing number of patients underwent RP as a possible first step within a multimodal concept.
Differences in the utilization of gestational surrogacy between states in the U.S.
Perkins, Kiran M; Boulet, Sheree L; Levine, Aaron D; Jamieson, Denise J; Kissin, Dmitry M
2018-04-01
Gestational surrogacy policy in the USA varies by state, but information on state differences is lacking. This study used data from the National Assisted Reproductive Technology Surveillance System from 2010 to 2014 to calculate state differences in gestational carrier cycle characteristics. Of the 662,165 in-vitro fertilization cycles in the USA between 2010 and 2014, 16,148 (2.4%) used gestational carriers. Non-USA residents accounted for 18.3% of gestational carrier cycles, and 29.1% of gestational carrier cycles by USA residents were performed in a state other than the state of residence of the intended parent. USA gestational surrogacy practice varies by state, potentially impacting patients' access to surrogacy services.
The Jewish contribution to medicine. Part III. The 19th and 20th centuries in the USA.
Dubovsky, H
1989-08-05
The Jewish hospital movement in the USA, which started in the last century for Jews as foreign immigrants and was extended to the general population this century, is an extensive organisation. Refugee physicians from Europe laid the foundations of Jewish medical involvement in medicine in the USA with Abraham Jacobi, the founder of paediatrics, Landsteiner, who discovered blood grouping, and Waksman, who evolved streptomycin. Other eminent workers, such as the Flexner brothers in medical education and research, Libman, who pioneered blood culture in the USA, and Salk and Sabin with the poliomyelitis vaccine were prominent in the major contribution of Jews to medicine in the USA.
1984-12-31
Ca. 90007 USA Eric C. Apel Dr. G. Comtet Department of Chemstry Department of Chemistry University of CAlifornia University of Californiai Irvine...Chicago Tempo, Az 85827 USA Chicago, Ill. 60637 USA - Professor R. Kopelman Professor S’. H. Lin Department of Chemistry Department of Chemstry . University...Nadler Department of Chemstry Ms. B. Lawrence University of Southern Calif. Department of Chemistry Los Angeles, Ca. 90007 USA University of California
1991-10-01
concentrations in the liquid phase. The role of the distribution coefficient in mitigating chemical migration is given in an approximation of nonuniform ...0.110 USA 60.0 12r- 990 1.11111 1219CN 0.230 USA 70.0 12-nor-199 Lull 12E1CM 0.240 UsA 80.0 12-spr-1990 LAIR 121PCN 0.260 USA 35.0 ?2-spr-I99 LOSl 121Cm
The Vietnam Cauldron: Defense Intelligence in the War for Southeast Asia
2012-01-01
For the Patriots. Major Robert P. Perry, USA Celeste M. Brown Vivienne A. Clark Dorothy M. Curtiss Joan K. Pray Doris J. Watkins Colonel Charles R. Ray...USA Chief Warrant Officer Robert W. Prescott, USA Chief Warrant Officer Kenneth D. Welch, USA Petty Officer First Class Michael R. Wagner, USN...Marshall Karl W. Teepe Patricia E. Mickley Robert J. Hymel Rosa M. Chapa Sandra N. Foster Charles E. Sabin i Defense Intelligence Historical Perspectives
The Eighth Data Release Of The Sloan Digital Sky Survey: First Data From SDSS-3
2011-04-01
Sunspot, NM 88349, USA 14 Center for Cosmology and Particle Physics, New York University, 4 Washington Place, New York, NY 10003, USA 15 Department of...Park, PA 16802, USA 18 Institute of Cosmology and Gravitation (ICG), Dennis Sciama Building, Burnaby Road, University of Portsmouth, Portsmouth, PO1 3FX... Cosmology , Carnegie Mellon University, Pittsburgh, P.A. 15213, USA 26 Yale Center for Astronomy and Astrophysics, Yale University, New Haven, CT 06520
High youth access to movies that contain smoking in Europe compared with the USA.
Hanewinkel, Reiner; Sargent, James D; Karlsdóttir, Sólveig; Jónsson, Stefán Hrafn; Mathis, Federica; Faggiano, Fabrizio; Poelen, Evelien A P; Scholte, Ron; Florek, Ewa; Sweeting, Helen; Hunt, Kate; Morgenstern, Matthis
2013-07-01
Based on evidence that exposure to smoking in movies is associated with adolescent smoking, the WHO has called on countries to assign a rating that restricts youth access to such movies. To evaluate youth access to movies that portray smoking in European countries and compare with that in the USA. The authors identified the most commercially successful movies screened in six European countries (Germany, Iceland, Italy, the Netherlands, Poland and UK) and the USA between 2004 and 2009. The authors coded the 464 movies that were screened in both Europe and the USA according to whether or not they portrayed smoking. 87% of the movies were 'youth' rated in Europe (ratings board classification as suitable for those younger than 16 years) compared to only 67% in the USA (suitable for those younger than 17 years). Smoking was portrayed in 319 (69%) movies. 85% of the movies that portrayed smoking were 'youth' rated in Europe compared with only 59% in the USA (p<0.001). Tobacco imagery is still common in popular films shown in European countries and the USA. None of the seven countries examined followed the WHO recommendations on restricting youth access to movies that portray smoking. Compared to the USA, European youths have access to substantially more movies in general, and this gives them access to more movies that portray smoking in particular.
Gonçalves, Vânia; Hudson, Janella; Canavarro, Maria Cristina; Morris, Julie; Lee, M Catherine; Donovan, Kristine A; Sutton, Steven K; Vadaparampil, Susan T; Quinn, Gwendolyn P
2018-04-16
To compare fertility and childbearing attitudes and decisions of Portuguese and American female reproductive aged breast cancer survivors. This was a cross-sectional study of 102 young breast cancer survivors (59 from Portugal and 43 from USA). Demographic, clinical and reproductive information were collected. Fertility and parenthood attitudes and decisions were assessed through a self-report questionnaire devised specifically for the study. Fertility issues became very important after the diagnosis for most of the women (51%). Few differences existed between USA and Portuguese participants. USA participants were more likely to undergo FP (23% USA vs Portugal 5%, p = 0.01). Portuguese women were more dissatisfied with their physician's explanations about fertility (Portugal: 23% vs USA: 3%; p = 0.01). Overall, women relied on their oncologist for fertility information (70%); only Portuguese women discussed fertility with their family medicine physician (11%). Overall, women showed positive attitudes towards motherhood. Portuguese women were more likely to report their partners placed more value on the family after their illness (Portuguese agree: 55% vs USA agree: 14%; p < 0.001). Fertility and childbearing after breast cancer are important issues regardless of culture, background or country's heath care system. Overall, few differences across the USA and Portuguese samples were found on fertility and childbearing attitudes and decisions. Copyright © 2018 Elsevier Ltd. All rights reserved.
OBIS-USA: a data-sharing legacy of the census of marine life
Sedberry, G.R.; Fautin, D.G.; Feldman, M.; Fornwall, M.D.; Goldstein, P.; Guralnick, R.P.
2011-01-01
The United States Geological Survey's Biological Informatics Program hosts OBIS-USA, the US node of the Ocean Biogeographic Information System (OBIS). OBIS-USA gathers, coordinates, applies standard formats to, and makeswidely available data on biological collections in marine waters of the United States and other areas where US investigators have collected data and, in some instances, specimens. OBIS-USA delivers its data to OBIS international, which then delivers its data to the Global Biodiversity Information Facility (GBIF) and other Web portals for marine biodiversity data. OBIS-USA currently has 145 data sets from 36 participants, representing over 6.5 million occurrence records of over 83,000 taxa from more than 888,000 locations. OBIS-USA, a legacy of the decade-long (2001-2010) international collaborative Census of Marine Life enterprise, continues to add data, including those from ongoing Census projects. Among the many challenges in creating OBIS, including OBIS-USA, were developing a community of trust and shared valueamong data providers, and demonstrating to providers the value of making their data accessible to others. Challenges also posed by the diversity of data sets relevant tomarine biodiversity stored on thousands of computers, in a variety of formats, not all widely accessible, have been met in OBIS-USA by implementing a uniform standard and publishing platform that is easily accessible to a broad range of users.
OBIS-USA: a data-sharing legacy of census of marine life
Sedberry, George R.; Fautin, Daphne G.; Feldman, Michael; Fornwall, Mark D.; Goldstein, Phillip; Guralnick, Robert P.
2011-01-01
The United States Geological Survey's Biological Informatics Program hosts OBIS-USA, the US node of the Ocean Biogeographic Information System (OBIS). OBIS-USA gathers, coordinates, applies standard formats to, and makes widely available data on biological collections in marine waters of the United States and other areas where US investigators have collected data and, in some instances, specimens. OBIS-USA delivers its data to OBIS international, which then delivers its data to the Global Biodiversity Information Facility (GBIF) and other Web portals for marine biodiversity data. OBIS-USA currently has 145 data sets from 36 participants, representing over 6.5 million occurrence records of over 83,000 taxa from more than 888,000 locations. OBIS-USA, a legacy of the decade-long (2001–2010) international collaborative Census of Marine Life enterprise, continues to add data, including those from ongoing Census projects. Among the many challenges in creating OBIS, including OBIS-USA, were developing a community of trust and shared value among data providers, and demonstrating to providers the value of making their data accessible to others. Challenges also posed by the diversity of data sets relevant to marine biodiversity stored on thousands of computers, in a variety of formats, not all widely accessible, have been met in OBIS-USA by implementing a uniform standard and publishing platform that is easily accessible to a broad range of users.
Eskildsen, Gilberto A; Rovira, Jose R; Smith, Octavio; Miller, Matthew J; Bennett, Kelly L; McMillan, W Owen; Loaiza, Jose
2018-01-01
Despite an increase in dengue outbreaks and the arrival of chikungunya and Zika disease in Panama, studies on the demographic history of the invasive Aedes mosquitoes that are the principle vectors of these diseases are still lacking in this region. Here, we assess the genetic diversity of these mosquitoes in order to decipher their invasion histories into the Isthmus of Panama. DNA sequences from the mitochondrial cytochrome C oxidase I gene obtained from 30 localities in 10 provinces confirmed the presence of more than one mitochondrial haplogroup (i.e., maternal lineage) in each species. The invasion of Aedes albopictus was likely from temperate European countries, as the most frequent and widespread haplogroup in Panama harbored variants that are uncommon elsewhere in the Americas. Two infrequent and geographically restricted Ae. albopictus haplotypes appear to have subsequently invaded Panama from neighboring Costa Rica and the USA, respectively. In addition, we recovered two deeply divergent mitochondrial clades in Panamanian Aedes aegypti. The geographic origins of these clades is unknown, given that divergence in the mitochondrial genome is probably due to ancient population processes within the native range of Ae. aegypti, rather than due to its global expansion out of Africa. However, Panamanian Ae. aegypti mitochondrial sequences within the first clade were closely related to others from Colombia, Bolivia, Brazil, Mexico and the USA, suggesting two separate invasions from Western Hemisphere source populations. The pattern of increased genetic diversity in Aedes mosquitoes in Panama is likely facilitated by the numerous land and water inter-connections across the country, which allows them to enter via sea- and land-transportation from Europe, North, Central and South America. Our results here should be considered in disease mitigation programs if emergent arboviruses are to be effectively diminished in Panama through vector suppression.
Type D Personality Predicts Poor Medication Adherence in Patients with Heart Failure in the USA
Wu, Jia-Rong; Moser, Debra K.
2015-01-01
Background Type D (distressed) personality and medication nonadherence have been associated with poor health outcomes. Type D personality is associated with poor medication adherence in patients with coronary artery disease. However, the relationship between type D personality and medication adherence in patients with heart failure (HF) remains unknown. Purpose Therefore, the goal of this study was to examine the association between type D personality and medication adherence in patients with HF. Method This was a sub-analysis of baseline data from a randomized controlled trial with 84 patients with HF in the USA. Demographic, clinical, and psychological data were collected at baseline by interview, questionnaires, and medical record review. Type D personality was assessed using the Type D Personality Scale (DS14). Medication adherence was measured using both objective (Medication Event Monitoring System, MEMS) and self-reported (Morisky Medication Adherence Scale, MMAS-4) measures. Patients started medication adherence monitoring with the MEMS bottle at baseline and is used continuously for a month. Multiple regressions were used to explore the relationships between type D personality and medication adherence while adjusting for demographic, clinical, and psychological factors. Results Patients with type D personality were more likely to have poor medication adherence. Type D personality was associated with medication adherence before and after adjusting for covariates when it was analyzed as a categorical variable. However, type D personality was not associated with medication adherence when analyzed as a dimensional construct. Negative affectivity, a component of type D personality, was associated with medication adherence. Conclusion As a dimensional construct, type D personality may not reflect the components of the personality associated with poor outcomes. Negative affectivity was associated with medication adherence in patients with HF. Interventions aiming to improving/enhancing medication adherence need to take into account patients with the negative affectivity component of type D personality who are at higher risk for poor medication adherence, which may lead to adverse health outcomes. PMID:24198039
Harmon, S Michele; West, Ryan T; Yates, James R
2014-12-01
Sources of fecal coliform pollution in a small South Carolina (USA) watershed were identified using inexpensive methods and commonly available equipment. Samples from the upper reaches of the watershed were analyzed with 3M(™) Petrifilm(™) count plates. We were able to narrow down the study's focus to one particular tributary, Sand River, that was the major contributor of the coliform pollution (both fecal and total) to a downstream reservoir that is heavily used for recreation purposes. Concentrations of total coliforms ranged from 2,400 to 120,333 cfu/100 mL, with sharp increases in coliform counts observed in samples taken after rain events. Positive correlations between turbidity and fecal coliform counts suggested a relationship between fecal pollution and stormwater runoff. Antibiotic resistance analysis (ARA) compared antibiotic resistance profiles of fecal coliform isolates from the stream to those of a watershed-specific fecal source library (equine, waterfowl, canines, and untreated sewage). Known fecal source isolates and unknown isolates from the stream were exposed to six antibiotics at three concentrations each. Discriminant analysis grouped known isolates with an overall average rate of correct classification (ARCC) of 84.3 %. A total of 401 isolates from the first stream location were classified as equine (45.9 %), sewage (39.4 %), waterfowl (6.2 %), and feline (8.5 %). A similar pattern was observed at the second sampling location, with 42.6 % equine, 45.2 % sewage, 2.8 % waterfowl, 0.6 % canine, and 8.8 % feline. While there were slight weather-dependent differences, the vast majority of the coliform pollution in this stream appeared to be from two sources, equine and sewage. This information will contribute to better land use decisions and further justify implementation of low-impact development practices within this urban watershed.
Eskildsen, Gilberto A.; Rovira, Jose R.; Smith, Octavio; Miller, Matthew J.; Bennett, Kelly L.; McMillan, W. Owen
2018-01-01
Despite an increase in dengue outbreaks and the arrival of chikungunya and Zika disease in Panama, studies on the demographic history of the invasive Aedes mosquitoes that are the principle vectors of these diseases are still lacking in this region. Here, we assess the genetic diversity of these mosquitoes in order to decipher their invasion histories into the Isthmus of Panama. DNA sequences from the mitochondrial cytochrome C oxidase I gene obtained from 30 localities in 10 provinces confirmed the presence of more than one mitochondrial haplogroup (i.e., maternal lineage) in each species. The invasion of Aedes albopictus was likely from temperate European countries, as the most frequent and widespread haplogroup in Panama harbored variants that are uncommon elsewhere in the Americas. Two infrequent and geographically restricted Ae. albopictus haplotypes appear to have subsequently invaded Panama from neighboring Costa Rica and the USA, respectively. In addition, we recovered two deeply divergent mitochondrial clades in Panamanian Aedes aegypti. The geographic origins of these clades is unknown, given that divergence in the mitochondrial genome is probably due to ancient population processes within the native range of Ae. aegypti, rather than due to its global expansion out of Africa. However, Panamanian Ae. aegypti mitochondrial sequences within the first clade were closely related to others from Colombia, Bolivia, Brazil, Mexico and the USA, suggesting two separate invasions from Western Hemisphere source populations. The pattern of increased genetic diversity in Aedes mosquitoes in Panama is likely facilitated by the numerous land and water inter-connections across the country, which allows them to enter via sea- and land-transportation from Europe, North, Central and South America. Our results here should be considered in disease mitigation programs if emergent arboviruses are to be effectively diminished in Panama through vector suppression. PMID:29579112
Seasonal changes in spatial patterns of two annual plants in the Chihuahuan Desert, USA
Yin, Z.-Y.; Guo, Q.; Ren, H.; Peng, S.-L.
2005-01-01
Spatial pattern of a biotic population may change over time as its component individuals grow or die out, but whether this is the case for desert annual plants is largely unknown. Here we examined seasonal changes in spatial patterns of two annuals, Eriogonum abertianum and Haplopappus gracilis, in initial (winter) and final (summer) densities. The density was measured as the number of individuals from 384 permanent quadrats (each 0.5 m × 0.5 m) in the Chihuahuan Desert near Portal, Arizona, USA. We used three probability distributions (binomial, Poisson, and negative binomial or NB) that represent three basic spatial patterns (regular, random, and clumped) to fit the observed frequency distributions of densities of the two annuals. Both species showed clear clumped patterns as characterized by the NB and had similar inverse J-shaped frequency distribution curves in two density categories. Also, both species displayed a reduced degree of aggregation from winter to summer after the spring drought (massive die-off), as indicated by the increased k-parameter of the NB and decreased values of another NB parameter p, variance/mean ratio, Lloyd’s Index of Patchiness, and David and Moore’s Index of Clumping. Further, we hypothesized that while the NB (i.e., Poisson-logarithmic) well fits the distribution of individuals per quadrat, its components, the Poisson and logarithmic, may describe the distributions of clumps per quadrat and of individuals per clump, respectively. We thus obtained the means and variances for (1) individuals per quadrat, (2) clumps per quadrat, and (3) individuals per clump. The results showed that the decrease of the density from winter to summer for each plant resulted from the decrease of individuals per clump, rather than from the decrease of clumps per quadrat. The great similarities between the two annuals indicate that our observed temporal changes in spatial patterns may be common among desert annual plants.
Avian and simian malaria: do they have a cancer connection?
Ward, Martin; Benelli, Giovanni
2017-03-01
It has been claimed that infectious agents transmitted by mosquitoes (Diptera: Culicidae) may have a greater connection to cancer then hitherto supposed and that the immune system struggles to recognize and fight some of these infectious agents. One of the claims made is that there is a connection between human malaria and brain cancers in the USA. However, the USA declared itself free of human malaria in the last century, yet cancer incidences remain high, suggesting any overall cancer connection is slight. Two fundamental questions arise from the possible mosquito-cancer connection. Firstly, if mosquitoes are able to vector some pathogens and parasites linked with cancer pathogenesis, why has the fact not been discovered decades ago? Secondly, if there is a connection (other than in relation to Burkett's lymphoma), what is its extent? The answers may well lie with the various types of malarias known to exist. The discovery in humans of the simian malaria, caused by Plasmodium knowlesi, suggests that other forms of simian or even avian malaria may be capable of survival in humans, albeit at low levels of parasitemia, and humans may be a dead-end host. Other carcinogenic infectious agents transmitted by mosquitoes may also go undetected because either no one is looking for them, or they are looking in wrong anatomical locations and/or with inadequate tools. Research on false negative test results with respect to many infectious agents is sadly lacking, so its extent is unknown. However, electronic and other media provide numerous instances of patients failing to be diagnosed for both human malaria and Lyme's disease, to take just two examples. This review suggests that to shed light on a potential mosquito-cancer connection, more research is required to establish whether other simian and avian forms of malaria play a part. If so, then they potentially provide unique markers for early cancer detection.
Potential economic burden of carbapenem-resistant Enterobacteriaceae (CRE) in the United States.
Bartsch, S M; McKinnell, J A; Mueller, L E; Miller, L G; Gohil, S K; Huang, S S; Lee, B Y
2017-01-01
The Centers for Disease Control and Prevention considers carbapenem-resistant Enterobacteriaceae (CRE) an urgent public health threat; however, its economic burden is unknown. We developed a CRE clinical and economics outcomes model to determine the cost of CRE infection from the hospital, third-party payer, and societal, perspectives and to evaluate the health and economic burden of CRE to the USA. Depending on the infection type, the median cost of a single CRE infection can range from $22 484 to $66 031 for hospitals, $10 440 to $31 621 for third-party payers, and $37 778 to $83 512 for society. An infection incidence of 2.93 per 100 000 population in the USA (9418 infections) would cost hospitals $275 million (95% CR $217-334 million), third-party payers $147 million (95% CR $129-172 million), and society $553 million (95% CR $303-1593 million) with a 25% attributable mortality, and would result in the loss of 8841 (95% CR 5805-12 420) quality-adjusted life years. An incidence of 15 per 100 000 (48 213 infections) would cost hospitals $1.4 billion (95% CR $1.1-1.7 billion), third-party payers $0.8 billion (95% CR $0.6-0.8 billion), and society $2.8 billion (95% CR $1.6-8.2 billion), and result in the loss of 45 261 quality-adjusted life years. The cost of CRE is higher than the annual cost of many chronic diseases and of many acute diseases. Costs rise proportionally with the incidence of CRE, increasing by 2.0 times, 3.4 times, and 5.1 times for incidence rates of 6, 10, and 15 per 100 000 persons. Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Wine, M. L.; Cadol, D.
2016-08-01
In recent years climate change and historic fire suppression have increased the frequency of large wildfires in the southwestern USA, motivating study of the hydrological consequences of these wildfires at point and watershed scales, typically over short periods of time. These studies have revealed that reduced soil infiltration capacity and reduced transpiration due to tree canopy combustion increase streamflow at the watershed scale. However, the degree to which these local increases in runoff propagate to larger scales—relevant to urban and agricultural water supply—remains largely unknown, particularly in semi-arid mountainous watersheds co-dominated by winter snowmelt and the North American monsoon. To address this question, we selected three New Mexico watersheds—the Jemez (1223 km2), Mogollon (191 km2), and Gila (4807 km2)—that together have been affected by over 100 wildfires since 1982. We then applied climate-driven linear models to test for effects of fire on streamflow metrics after controlling for climatic variability. Here we show that, after controlling for climatic and snowpack variability, significantly more streamflow discharged from the Gila watershed for three to five years following wildfires, consistent with increased regional water yield due to enhanced infiltration-excess overland flow and groundwater recharge at the large watershed scale. In contrast, we observed no such increase in discharge from the Jemez watershed following wildfires. Fire regimes represent a key difference between the contrasting responses of the Jemez and Gila watersheds with the latter experiencing more frequent wildfires, many caused by lightning strikes. While hydrologic dynamics at the scale of large watersheds were previously thought to be climatically dominated, these results suggest that if one fifth or more of a large watershed has been burned in the previous three to five years, significant increases in water yield can be expected.
Milting, Hendrik; Klauke, Bärbel; Christensen, Alex Hoerby; Müsebeck, Jörg; Walhorn, Volker; Grannemann, Sören; Münnich, Tamara; Šarić, Tomo; Rasmussen, Torsten Bloch; Jensen, Henrik Kjærulf; Mogensen, Jens; Baecker, Carolin; Romaker, Elena; Laser, Kai Thorsten; zu Knyphausen, Edzard; Kassner, Astrid; Gummert, Jan; Judge, Daniel P; Connors, Sean; Hodgkinson, Kathy; Young, Terry-L; van der Zwaag, Paul A; van Tintelen, J Peter; Anselmetti, Dario
2015-04-07
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare genetic condition caused predominantly by mutations within desmosomal genes. The mutation leading to ARVC-5 was recently identified on the island of Newfoundland and caused by the fully penetrant missense mutation p.S358L in TMEM43. Although TMEM43-p.S358L mutation carriers were also found in the USA, Germany, and Denmark, the genetic relationship between North American and European patients and the disease mechanism of this mutation remained to be clarified. We screened 22 unrelated ARVC patients without mutations in desmosomal genes and identified the TMEM43-p.S358L mutation in a German ARVC family. We excluded TMEM43-p.S358L in 22 unrelated patients with dilated cardiomyopathy. The German family shares a common haplotype with those from Newfoundland, USA, and Denmark, suggesting that the mutation originated from a common founder. Examination of 40 control chromosomes revealed an estimated age of 1300-1500 years for the mutation, which proves the European origin of the Newfoundland mutation. Skin fibroblasts from a female and two male mutation carriers were analysed in cell culture using atomic force microscopy and revealed that the cell nuclei exhibit an increased stiffness compared with TMEM43 wild-type controls. The German family is not affected by a de novo TMEM43 mutation. It is therefore expected that an unknown number of European families may be affected by the TMEM43-p.S358L founder mutation. Due to its deleterious clinical phenotype, this mutation should be checked in any case of ARVC-related genotyping. It appears that the increased stiffness of the cell nucleus might be related to the massive loss of cardiomyocytes, which is typically found in ventricles of ARVC hearts. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.
Towards smoke-free rental cars: an evaluation of voluntary smoking restrictions in California.
Matt, Georg E; Fortmann, Addie L; Quintana, Penelope J E; Zakarian, Joy M; Romero, Romina A; Chatfield, Dale A; Hoh, Eunha; Hovell, Melbourne F
2013-05-01
Some car rental companies in California and other states in the USA have established non-smoking policies for their vehicles. This study examined the effectiveness of these policies in maintaining smoke-free rental cars. A stratified random sample of 250 cars (non-smoker, smoker and unknown designation) was examined in San Diego County, California, USA. Dust, surfaces and the air of each vehicle cabin were sampled and analysed for residual tobacco smoke pollutants (also known as thirdhand smoke (THS)), and each car was inspected for visual and olfactory signs of tobacco use. Customer service representatives were informally interviewed about smoking policies. A majority of putative non-smoker cars had nicotine in dust, on surfaces, in air and other signs of tobacco use. Independent of a car's smoking status, older and higher mileage cars had higher levels of THS pollution in dust and on surfaces (p<0.05), indicating that pollutants accumulated over time. Compared with smoker cars, non-smoker cars had lower levels of nicotine on surfaces (p<0.01) and in dust (p<0.05) and lower levels of nicotine (p<0.05) and 3-ethynylpyridine (p<0.05) in the air. Non-smoking signage in cars was associated with lower levels of THS pollutants in dust and air (p<0.05). Existing policies and practices were successful in lowering THS pollution levels in non-smoker cars compared with smoker cars. However, policies failed in providing smoke-free rental cars; THS levels were not as low as those found in private cars of non-smokers with in-car smoking bans. Major obstacles include inconsistent communication with customers and the lack of routine monitoring and enforcement strategies. Strengthening policies and their implementation would allow car rental companies to reduce costs, better serve their customers and make a constructive contribution to tobacco control efforts.
Tree City USA is a national program that recognizes municipal commitment to community forestry. In return for meeting program requirements, Tree City USA participants expect social, economic, and/or environmental benefits. Understandingthe geographic distribution and socioeconomi...
2016-01-01
The pathway from simple abiotically made organic compounds to the molecular bricks of life, as we know it, is unknown. The most efficient geological abiotic route to organic compounds results from the aqueous dissolution of olivine, a reaction known as serpentinization (Sleep, N.H., et al. (2004) Proc. Natl. Acad. Sci. USA 101, 12818–12822). In addition to molecular hydrogen and a reducing environment, serpentinization reactions lead to high-pH alkaline brines that can become easily enriched in silica. Under these chemical conditions, the formation of self-assembled nanocrystalline mineral composites, namely silica/carbonate biomorphs and metal silicate hydrate (MSH) tubular membranes (silica gardens), is unavoidable (Kellermeier, M., et al. In Methods in Enzymology, Research Methods in Biomineralization Science (De Yoreo, J., Ed.) Vol. 532, pp 225–256, Academic Press, Burlington, MA). The osmotically driven membranous structures have remarkable catalytic properties that could be operating in the reducing organic-rich chemical pot in which they form. Among one-carbon compounds, formamide (NH2CHO) has been shown to trigger the formation of complex prebiotic molecules under mineral-driven catalytic conditions (Saladino, R., et al. (2001) Biorganic & Medicinal Chemistry, 9, 1249–1253), proton irradiation (Saladino, R., et al. (2015) Proc. Natl. Acad. Sci. USA, 112, 2746–2755), and laser-induced dielectric breakdown (Ferus, M., et al. (2015) Proc Natl Acad Sci USA, 112, 657–662). Here, we show that MSH membranes are catalysts for the condensation of NH2CHO, yielding prebiotically relevant compounds, including carboxylic acids, amino acids, and nucleobases. Membranes formed by the reaction of alkaline (pH 12) sodium silicate solutions with MgSO4 and Fe2(SO4)3·9H2O show the highest efficiency, while reactions with CuCl2·2H2O, ZnCl2, FeCl2·4H2O, and MnCl2·4H2O showed lower reactivities. The collections of compounds forming inside and outside the tubular membrane are clearly specific, demonstrating that the mineral self-assembled membranes at the same time create space compartmentalization and selective catalysis of the synthesis of relevant compounds. Rather than requiring odd local conditions, the prebiotic organic chemistry scenario for the origin of life appears to be common at a universal scale and, most probably, earlier than ever thought for our planet. PMID:27115539
Goldstein, Tracey; Gill, Verena A.; Tuomi, Pamela A.; Monson, Daniel H.; Burdin, Alexander; Conrad, Patricia A.; Dunn, J. Lawrence; Field, Cara L.; Johnson, Christine K.; Jessup, David A.; Bodkin, James L.; Doroff, Angela M.
2011-01-01
Northern sea otter (Enhydra lutris kenyoni) abundance has decreased dramatically over portions of southwest Alaska, USA, since the mid-1980s, and this stock is currently listed as threatened under the Endangered Species Act. In contrast, adjacent populations in south central Alaska, USA, and Russia have been stable to increasing during the same period. Sea otters bordering the area classified in the recent decline were live-captured during 2004–2006 at Bering Island, Russia, and the Kodiak Archipelago, Alaska, USA, to evaluate differences in general health and current exposure status to marine and terrestrial pathogens. Although body condition was lower in animals captured at Bering Island, Russia, than it was at Kodiak, USA, clinical pathology values did not reveal differences in general health between the two regions. Low prevalences of antibodies (>5%) were found in Kodiak, USA, and on Bering Island, Russia, to Toxoplasma gondii, Sarcocystis neurona, and Leptospira interrogans. Exposure to phocine herpesvirus-1 was found in both Kodiak, USA (15.2%), and Bering Island, Russia (2.3%). Antibodies to Brucella spp. were found in 28% of the otters tested on Bering Island, Russia, compared with only 2.7% of the samples from Kodiak, USA. Prevalence of exposure to Phocine distemper virus (PDV) was 41% in Kodiak, USA, but 0% on Bering Island, Russia. Archived sera from southwest and south-central Alaska dating back to 1989 were negative for PDV, indicating exposure occurred in sea otters in Kodiak, USA, in recent years. Because PDV can be highly pathogenic in naïve and susceptible marine mammal populations, tissues should be examined to explore the contribution of this virus to otter deaths. Our results reveal an increase in exposure to pathogens in sea otters in Kodiak, Alaska, USA, since the 1990s.
Can genomics clarify the origins of Boreioglycaspis melaleucae in California, USA?
USDA-ARS?s Scientific Manuscript database
The Australian psyllid Boreioglycaspis melaleucae is a biological control agent of Melaleuca quinquenervia in Florida (USA) but was observed attacking M. quinquenervia trees in southern California (USA). Genotyping revealed the California population matched three of eight Australian haplotypes and ...
Public Notice: Proposed Land Ban Exemption to Ineos USA LLC
Public notice for proposed Land Ban Exemption Reissuance, for Ineos USA LLC, to continue to inject hazardous waste deep underground in Allen County, OH. EPA plans to reissue a Land Ban Exemption for Ineos USA LLC in Allen Co., OH.
USA Science and Engineering Festival 2014
2014-04-25
Attendees of the USA Science and Engineering Festival explore all of the exhibits at the NASA Stage. The USA Science and Engineering Festival took place at the Washington Convention Center in Washington, DC on April 26 and 27, 2014. Photo Credit: (NASA/Aubrey Gemignani)
Defense Science Board Force Protection Panel Report to DSB
1997-12-01
John Cowan, Jr., USMC USMC-MCCDC COL Dan Hahn, USA J-34 COL Hal Johnson, USA J-34 OPS Mr. Paul Kozemchak DARPA/ISO Mr. Roberto Mata ATSD(NCB)/CP CAPT...Ame Nelson, USN OPNAV N312 COL Robert Neubert , USA Army DCSOPS LtCol Roby, USAF AF/XOIIA Mr. John J. Sloan Defense Intelligence Agency Mr. Dan Spohn...Ame Nelson, USN 33. US Army Force Protection Budget: COL Robert Neubert , USA 34. US Marine Corps Force Protection Budget: LtCol Street, USMC 35. CBT
Côrtes, Marina Farrel; Costa, Maiana OC; Lima, Nicholas CB; Souza, Rangel C; Almeida, Luiz GP; Guedes, Luciane Prioli Ciapina; Vasconcelos, Ana TR; Nicolás, Marisa F; Figueiredo, Agnes MS
2017-01-01
Staphylococcus aureus subsp. aureus, commonly referred as S. aureus, is an important bacterial pathogen frequently involved in hospital- and community-acquired infections in humans, ranging from skin infections to more severe diseases such as pneumonia, bacteraemia, endocarditis, osteomyelitis, and disseminated infections. Here, we report the complete closed genome sequence of a community-acquired methicillin-resistant S. aureus strain, USA400-0051, which is a prototype of the USA400 clone. PMID:29091141
System Hazard Analysis of TACOM’s Crew Station/Turret Motion Base Simulator
1992-01-01
Safety devices have been located on the equipment where necessary and are described in the Contraves USA Manual No. IM-27751, "INSTRUCTION MANUAL FOR...OF TACOM’s CREW STATION/TURRET MOTION BASE SIMULATOR" and Contraves USA Manual No. IM-27751, "INSTRUCTION MANUAL FOR TACOM" in an attempt to satisfy... Contraves USA and assembled jointly by Contraves USA and TACOM. All control compensation was performed by TACOM. The CS/TMBS is expected to open doors
2007-03-01
Contaminant Concentrations in Storm Water Entering the Sinclair/Dyes Inlet Subasin of the Puget Sound , USA During Storm Event and Baseflow Conditions...Johnston1 (Space and Naval Warfare Systems Center, Bremerton, WA, USA), Dwight E. Leisle, Bruce Beckwith, and Gerald Sherrell ( Puget Sound Naval Shipyard...The Sinclair and Dyes Inlet watershed is located on the west side of Puget Sound in Kitsap County, Washington, U.S.A. (Figure 1). Puget Sound Naval
Murray, A C; Markar, S; Mackenzie, H; Baser, O; Wiggins, T; Askari, A; Hanna, G; Faiz, O; Mayer, E; Bicknell, C; Darzi, A; Kiran, R P
2018-01-08
Evidence supports early laparoscopic cholecystectomy for acute cholecystitis. Differences in treatment patterns between the USA and UK, associated outcomes and resource utilization are not well understood. In this retrospective, observational study using national administrative data, emergency patients admitted with acute cholecystitis were identified in England (Hospital Episode Statistics 1998-2012) and USA (National Inpatient Sample 1998-2011). Proportions of patients who underwent emergency cholecystectomy, utilization of laparoscopy and associated outcomes including length of stay (LOS) and complications were compared. The effect of delayed treatment on subsequent readmissions was evaluated for England. Patients with a diagnosis of acute cholecystitis totaled 1,191,331 in the USA vs. 288 907 in England. Emergency cholecystectomy was performed in 628,395 (52.7% USA) and 45,299 (15.7% England) over the time period. Laparoscopy was more common in the USA (82.8 vs. 37.9%; p < 0.001). Pre-treatment (1 vs. 2 days; p < 0.001) and total ( 4 vs. 7 days; p < 0.001) LOS was lower in the USA. Overall incidence of bile duct injury was higher in England than the USA (0.83 vs. 0.43%; p < 0.001), but was no different following laparoscopic surgery (0.1%). In England, 40.5% of patients without an immediate cholecystectomy were subsequently readmitted with cholecystitis. An additional 14.5% were admitted for other biliary complications, amounting to 2.7 readmissions per patient in the year following primary admission. This study highlights management practices for acute cholecystitis in the USA and England. Despite best evidence, index admission laparoscopic cholecystectomy is performed less in England, which significantly impacts subsequent healthcare utilization.
NASA Astrophysics Data System (ADS)
2004-10-01
Fritz Caspers (CERN, Switzerland), Michel Chanel (CERN, Switzerland), Håkan Danared (MSL, Sweden), Bernhard Franzke (GSI, Germany), Manfred Grieser (MPI für Kernphysik, Germany), Dieter Habs (LMU München, Germany), Jeffrey Hangst (University of Aarhus, Denmark), Takeshi Katayama (RIKEN/Univ. Tokyo, Japan), H.-Jürgen Kluge (GSI, Germany), Shyh-Yuan Lee (Indiana University, USA), Rudolf Maier (FZ Jülich, Germany), John Marriner (FNAL, USA), Igor Meshkov (JINR, Russia), Dieter Möhl (CERN, Switzerland), Vasily Parkhomchuk (BINP, Russia), Robert Pollock (Indiana University), Dieter Prasuhn (FZ Jülich, Germany), Dag Reistad (TSL, Sweden), John Schiffer (ANL, USA), Andrew Sessler (LBNL, USA), Alexander Skrinsky (BINP, Russia), Markus Steck (GSI, Germany), Jie Wei (BNL, USA), Andreas Wolf (MPI für Kernphysik, Germany), Hongwei Zhao (IMP, People's Rep. of China).
76 FR 3621 - Combined Notice of Filings #1
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-20
.... Eastern Time on Monday, January 31, 2011. Docket Numbers: ER11-2166-001. Applicants: Planet Energy (USA) Corp. Description: Planet Energy (USA) Corp. submits tariff filing per 35.17(b): Planet Energy USA.... Applicants: Planet Energy (Pennsylvania) Corp. Description: Planet Energy (Pennsylvania) Corp. submits tariff...
Hadley, Craig; Patil, Crystal
2009-12-01
The objectives of this study were to assess the prevalence and predictors of discrimination among a community-based sample of refugees resettled in the USA. We sought to test whether language, gender, time in the USA and country of origin were associated with the experience of discrimination among individuals resettled in the USA as part of the refugee resettlement program. Perceived discrimination was assessed among individuals from East Africa (n = 92), West Africa (n = 74), and from Eastern Europe (n = 112) using a multi-item measure of discrimination. Bivariate associations revealed statistically significant associations between experiences of discrimination and time in the USA, language ability, and sending country. A logistic regression model revealed that refugees from African sending countries were more likely than Eastern European individuals to experience discrimination, even after controlling for potentially confounding factors. We interpret this finding as evidence of racism and discuss the implications for population health and resettlement practice.
2003-12-19
KENNEDY SPACE CENTER, FLA. -- NASA and United Space Alliance (USA) Space Shuttle program managers attend a briefing, part of activities during a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC. Starting third from left are NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik, USA Vice President and Space Shuttle Program Manager Howard DeCastro, NASA Space Shuttle Program Manager William Parsons, and USA Associate Program Manager of Ground Operations Andy Allen.
2003-12-19
KENNEDY SPACE CENTER, FLA. -- From left, NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro, NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik, and a USA technician examine cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.
2003-12-19
KENNEDY SPACE CENTER, FLA. -- United Space Alliance (USA) technicians demonstrate the construction of a thermal blanket used in the Shuttle's thermal protection system for USA Vice President and Space Shuttle Program Manager Howard DeCastro (second from left) and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik (right). NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.
2003-12-19
KENNEDY SPACE CENTER, FLA. -- From left, a United Space Alliance (USA) technician discusses aspects of Shuttle processing performed in the Solid Rocket Booster (SRB) Assembly and Refurbishment Facility (ARF) with USA Vice President and Space Shuttle Program Manager Howard DeCastro and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.
2003-12-19
KENNEDY SPACE CENTER, FLA. -- United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro (left) and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik (center) are briefed on the use of a cold plate in Orbiter Processing Facility Bay 2 by a USA technician (right). NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.
2003-12-19
KENNEDY SPACE CENTER, FLA. -- In Orbiter Processing Facility Bay 1, NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik (left) and United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro (right) are briefed by a USA technician (center) on Shuttle processing in the payload bay of orbiter Atlantis. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.
2003-12-19
KENNEDY SPACE CENTER, FLA. -- United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro (left) and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik (third from left) watch as a USA technician (right) creates a tile for use in the Shuttle's Thermal Protection System (TPS). NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.
Evidence-Based Redesign of the COMLEX-USA Series.
Gimpel, John R; Horber, Dorothy; Sandella, Jeanne M; Knebl, Janice A; Thornburg, John E
2017-04-01
To ensure that the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) reflects the evolving practice of osteopathic medicine, the National Board of Osteopathic Medical Examiners has developed new content and format specifications for an enhanced, competency-based examination program to be implemented with COMLEX-USA Level 3 in 2018. This article summarizes the evidence-based design processes that served as the foundation for blueprint development and the evidence supporting its validity. An overview is provided of the blueprint's 2 dimensions: Competency Domains and Clinical Presentations. The authors focus on the evidence that supports interpretation of test scores for the primary and intended purpose of COMLEX-USA, which is osteopathic physician licensure. Important secondary uses and the educational and catalytic effect of assessments are also described. This article concludes with the National Board of Osteopathic Medical Examiners' plans to ensure that the COMLEX-USA series remains current and meets the needs of its stakeholders-the patients who seek care from osteopathic physicians.
The methodological and reporting quality of systematic reviews from China and the USA are similar.
Tian, Jinhui; Zhang, Jun; Ge, Long; Yang, Kehu; Song, Fujian
2017-05-01
To compare the methodological and reporting quality of systematic reviews by authors from China and those from the United States (USA). From systematic reviews of randomized trials published in 2014 in English, we randomly selected 100 from China and 100 from the USA. The methodological quality was assessed using the Assessing the Methodological Quality of Systematic Reviews (AMSTAR) tool, and reporting quality assessed using the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) tool. Compared with systematic reviews from the USA, those from China were more likely to be a meta-analysis, published in low-impact journals, and a non-Cochrane review. The mean summary Assessing the Methodological Quality of Systematic Reviews score was 6.7 (95% confidence interval: 6.5, 7.0) for reviews from China and 6.6 (6.1, 7.1) for reviews from the USA, and the mean summary Preferred Reporting Items for Systematic Reviews and Meta-analyses score was 21.2 (20.7, 21.6) for reviews from China and 20.6 (19.9, 21.3) for reviews from the USA. The differences in summary quality scores between China and the USA were statistically nonsignificant after adjusting for multiple review factors. The overall methodological and reporting quality of systematic reviews by authors from China are similar to those from the USA, although the quality of systematic reviews from both countries could be further improved. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.
Villaseñor-Sierra, Alberto; Katahira, Eva; Jaramillo-Valdivia, Abril N.; de los Angeles Barajas-García, María; Bryant, Amy; Morfín-Otero, Rayo; Márquez-Díaz, Francisco; Tinoco, Juan Carlos; Sánchez-Corona, José; Stevens, Dennis L.
2012-01-01
Summary Objective To compare the prevalence, phenotypes, and genes responsible for erythromycin resistance among Streptococcus pyogenes isolates from Mexico and the USA. Methods Eighty-nine invasive and 378 non-invasive isolates from Mexico, plus 148 invasive, 21 non-invasive, and five unclassified isolates from the USA were studied. Susceptibilities to penicillin, erythromycin, clindamycin, ceftriaxone, and vancomycin were evaluated according to Clinical and Laboratory Standards Institute (CLSI) standards. Phenotypes of erythromycin resistance were identified by triple disk test, and screening for mefA, ermTR, and ermB genes was carried out by PCR. Results All isolates were susceptible to penicillin, ceftriaxone, and vancomycin. Erythromycin resistance was found in 4.9% of Mexican strains and 5.2% of USA strains. Phenotypes in Mexican strains were 95% M and 5% cMLS; in strains from the USA, phenotypes were 33.3% iMLS, 33.3% iMLS-D, and 33.3% M. Erythromycin resistance genes in strains from Mexico were mefA (95%) and ermB (5%); USA strains harbored ermTR (56%), mefA (33%), and none (11%). In Mexico, all erythromycin-resistant strains were non-invasive, whereas 89% of strains from the USA were invasive. Conclusions Erythromycin resistance continues to exist at low levels in both Mexico and the USA, although the genetic mechanisms responsible differ between the two nations. These genetic differences may be related to the invasive character of the S. pyogenes isolated. PMID:22217469
High youth access to movies that contain smoking in Europe compared with the USA
Hanewinkel, Reiner; Sargent, James D; Karlsdóttir, Sólveig; Jónsson, Stefán Hrafn; Mathis, Federica; Faggiano, Fabrizio; Poelen, Evelien A P; Scholte, Ron; Florek, Ewa; Sweeting, Helen; Hunt, Kate; Morgenstern, Matthis
2013-01-01
Background Based on evidence that exposure to smoking in movies is associated with adolescent smoking, the WHO has called on countries to assign a rating that restricts youth access to such movies. Objective To evaluate youth access to movies that portray smoking in European countries and compare with that in the USA. Methods The authors identified the most commercially successful movies screened in six European countries (Germany, Iceland, Italy, the Netherlands, Poland and UK) and the USA between 2004 and 2009. The authors coded the 464 movies that were screened in both Europe and the USA according to whether or not they portrayed smoking. Results 87% of the movies were ‘youth’ rated in Europe (ratings board classification as suitable for those younger than 16 years) compared to only 67% in the USA (suitable for those younger than 17 years). Smoking was portrayed in 319 (69%) movies. 85% of the movies that portrayed smoking were ‘youth’ rated in Europe compared with only 59% in the USA (p<0.001). Conclusions Tobacco imagery is still common in popular films shown in European countries and the USA. None of the seven countries examined followed the WHO recommendations on restricting youth access to movies that portray smoking. Compared to the USA, European youths have access to substantially more movies in general, and this gives them access to more movies that portray smoking in particular. PMID:22184208
USA Science and Engineering Festival 2014
2014-04-25
An attendee of the USA Science and Engineering Festival uses marbles to build a universe consisting of atoms and dark matter. The USA Science and Engineering Festival took place at the Washington Convention Center in Washington, DC on April 26 and 27, 2014. Photo Credit: (NASA/Aubrey Gemignani)
ULTRAVIOLET RADIATION DOSE AND AMPHIBIAN DISTRIBUTIONS IN NATIONAL PARKS
Ultraviolet Radiation Dose and Amphibian Distributions in National Parks. Diamond, S. A., Detenbeck, N. E., USEPA, Duluth, MN, USA, Bradford, D. F., USEPA, Las Vegas, NV, USA, Trenham, P. C., University of California, Davis, CA., USA, Adams, M. J., Corn, P. S., Hossack, B., USGS,...
75 FR 74707 - Combined Notice of Filings #1
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-01
...-000. Applicants: Planet Energy (USA) Corp. Description: Planet Energy (USA) Corp. submits tariff filing per 35.1: Planet Energy USA MBR Application to be effective 11/22/2010. Filed Date: 11/22/2010... Numbers: ER11-2167-000. Applicants: Planet Energy (Pennsylvania) Corp. Description: Planet Energy...
PREFACE: International Conference on Computing in High Energy and Nuclear Physics (CHEP 2010)
NASA Astrophysics Data System (ADS)
Lin, Simon C.; Shen, Stella; Neufeld, Niko; Gutsche, Oliver; Cattaneo, Marco; Fisk, Ian; Panzer-Steindel, Bernd; Di Meglio, Alberto; Lokajicek, Milos
2011-12-01
The International Conference on Computing in High Energy and Nuclear Physics (CHEP) was held at Academia Sinica in Taipei from 18-22 October 2010. CHEP is a major series of international conferences for physicists and computing professionals from the worldwide High Energy and Nuclear Physics community, Computer Science, and Information Technology. The CHEP conference provides an international forum to exchange information on computing progress and needs for the community, and to review recent, ongoing and future activities. CHEP conferences are held at roughly 18 month intervals, alternating between Europe, Asia, America and other parts of the world. Recent CHEP conferences have been held in Prauge, Czech Republic (2009); Victoria, Canada (2007); Mumbai, India (2006); Interlaken, Switzerland (2004); San Diego, California(2003); Beijing, China (2001); Padova, Italy (2000) CHEP 2010 was organized by Academia Sinica Grid Computing Centre. There was an International Advisory Committee (IAC) setting the overall themes of the conference, a Programme Committee (PC) responsible for the content, as well as Conference Secretariat responsible for the conference infrastructure. There were over 500 attendees with a program that included plenary sessions of invited speakers, a number of parallel sessions comprising around 260 oral and 200 poster presentations, and industrial exhibitions. We thank all the presenters, for the excellent scientific content of their contributions to the conference. Conference tracks covered topics on Online Computing, Event Processing, Software Engineering, Data Stores, and Databases, Distributed Processing and Analysis, Computing Fabrics and Networking Technologies, Grid and Cloud Middleware, and Collaborative Tools. The conference included excursions to various attractions in Northern Taiwan, including Sanhsia Tsu Shih Temple, Yingko, Chiufen Village, the Northeast Coast National Scenic Area, Keelung, Yehliu Geopark, and Wulai Aboriginal Village, as well as two banquets held at the Grand Hotel and Grand Formosa Regent in Taipei. The next CHEP conference will be held in New York, the United States on 21-25 May 2012. We would like to thank the National Science Council of Taiwan, the EU ACEOLE project, commercial sponsors, and the International Advisory Committee and the Programme Committee members for all their support and help. Special thanks to the Programme Committee members for their careful choice of conference contributions and enormous effort in reviewing and editing about 340 post conference proceedings papers. Simon C Lin CHEP 2010 Conference Chair and Proceedings Editor Taipei, Taiwan November 2011 Track Editors/ Programme Committee Chair Simon C Lin, Academia Sinica, Taiwan Online Computing Track Y H Chang, National Central University, Taiwan Harry Cheung, Fermilab, USA Niko Neufeld, CERN, Switzerland Event Processing Track Fabio Cossutti, INFN Trieste, Italy Oliver Gutsche, Fermilab, USA Ryosuke Itoh, KEK, Japan Software Engineering, Data Stores, and Databases Track Marco Cattaneo, CERN, Switzerland Gang Chen, Chinese Academy of Sciences, China Stefan Roiser, CERN, Switzerland Distributed Processing and Analysis Track Kai-Feng Chen, National Taiwan University, Taiwan Ulrik Egede, Imperial College London, UK Ian Fisk, Fermilab, USA Fons Rademakers, CERN, Switzerland Torre Wenaus, BNL, USA Computing Fabrics and Networking Technologies Track Harvey Newman, Caltech, USA Bernd Panzer-Steindel, CERN, Switzerland Antonio Wong, BNL, USA Ian Fisk, Fermilab, USA Niko Neufeld, CERN, Switzerland Grid and Cloud Middleware Track Alberto Di Meglio, CERN, Switzerland Markus Schulz, CERN, Switzerland Collaborative Tools Track Joao Correia Fernandes, CERN, Switzerland Philippe Galvez, Caltech, USA Milos Lokajicek, FZU Prague, Czech Republic International Advisory Committee Chair: Simon C. Lin , Academia Sinica, Taiwan Members: Mohammad Al-Turany , FAIR, Germany Sunanda Banerjee, Fermilab, USA Dario Barberis, CERN & Genoa University/INFN, Switzerland Lothar Bauerdick, Fermilab, USA Ian Bird, CERN, Switzerland Amber Boehnlein, US Department of Energy, USA Kors Bos, CERN, Switzerland Federico Carminati, CERN, Switzerland Philippe Charpentier, CERN, Switzerland Gang Chen, Institute of High Energy Physics, China Peter Clarke, University of Edinburgh, UK Michael Ernst, Brookhaven National Laboratory, USA David Foster, CERN, Switzerland Merino Gonzalo, CIEMAT, Spain John Gordon, STFC-RAL, UK Volker Guelzow, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany John Harvey, CERN, Switzerland Frederic Hemmer, CERN, Switzerland Hafeez Hoorani, NCP, Pakistan Viatcheslav Ilyin, Moscow State University, Russia Matthias Kasemann, DESY, Germany Nobuhiko Katayama, KEK, Japan Milos Lokajícek, FZU Prague, Czech Republic David Malon, ANL, USA Pere Mato Vila, CERN, Switzerland Mirco Mazzucato, INFN CNAF, Italy Richard Mount, SLAC, USA Harvey Newman, Caltech, USA Mitsuaki Nozaki, KEK, Japan Farid Ould-Saada, University of Oslo, Norway Ruth Pordes, Fermilab, USA Hiroshi Sakamoto, The University of Tokyo, Japan Alberto Santoro, UERJ, Brazil Jim Shank, Boston University, USA Alan Silverman, CERN, Switzerland Randy Sobie , University of Victoria, Canada Dongchul Son, Kyungpook National University, South Korea Reda Tafirout , TRIUMF, Canada Victoria White, Fermilab, USA Guy Wormser, LAL, France Frank Wuerthwein, UCSD, USA Charles Young, SLAC, USA
USDA-ARS?s Scientific Manuscript database
Semiarid rangelands in the western USA are facing serious challenges related to past mismanagement, invasive weedy species, wildfires, and climatic change. Leguminous forbs that are native to the western USA are of interest for rangeland revegetation and restoration because they provide biologicall...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-22
... DEPARTMENT OF COMMERCE [Docket T-1-2010] Foreign-Trade Zones Board Foreign-Trade Zone 22; Temporary/Interim Manufacturing Authority; LG Electronics Mobilecomm USA, Inc. (Cell Phones); Notice of.../ interim manufacturing (T/IM) authority, on behalf of LG Electronics Mobilecomm USA, Inc. (LGEMU), to...
78 FR 69659 - Chevron U.S.A. Inc. v. Kinder Morgan Louisiana Pipeline LLC; Notice of Complaint
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-20
... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RP14-161-000] Chevron U.S.A... Commission (Commission), 18 CFR 385.206, Chevron U.S.A. Inc. (Chevron or Complainant), filed a complaint..., Commission policy, and contractual obligations. [[Page 69660
76 FR 21407 - Manufacturer of Controlled Substances Notice of Registration
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-15
... 3, 2010, 75 FR 75497, Siegfried (USA), Inc., 33 Industrial Park Road, Pennsville, New Jersey 08070... the factors in 21 U.S.C. 823(a) and determined that the registration of Siegfried (USA), Inc. to.... DEA has investigated Siegfried (USA), Inc. to ensure that the company's registration is consistent...
76 FR 21916 - Manufacturer of Controlled Substances; Notice of Registration
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-19
... December 29, 2010, 75 FR 82073, Siegfried (USA), Inc., 33 Industrial Park Road, Pennsville, New Jersey... registration of Siegfried (USA), Inc. to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Siegfried (USA), Inc. to ensure that...
75 FR 44287 - Manufacturer of Controlled Substances; Notice of Registration
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-28
..., 2010, (75 FR 14189), Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey 08070, made... determined that the registration of Siegfried (USA) to manufacture the listed basic classes of controlled substances is consistent with the public interest at this time. DEA has investigated Siegfried (USA) to...
75 FR 62570 - Manufacturer of Controlled Substances; Notice of Registration
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-12
..., 2010 (75 FR 36683), Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey 08070, made... considered the factors in 21 U.S.C. 823(a) and determined that the registration of Siegfried (USA) to.... DEA has investigated Siegfried (USA) to ensure that the company's registration is consistent with the...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-29
... Secure Solutions USA, SBM Management Services, LP, ALSCO Portland Industrial, VWR International, Inc... G4S Secure Solutions USA, SBM Management Services, LP, Alsco Portland Industrial, VWR International... workers from Express Temporaries, Aerotek Commercial Staffing, G4S Secure Solutions USA, SBM Management...
76 FR 67730 - Ocean Transportation Intermediary License Applicants
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-02
... Type: New OFF License LF Freight USA LLC dba LF Logistics dba LF Freight dba IDS Logistics USA, dba IDS Freight Services, dba AGI Logistics USA, dba AGI Logistics, 230-59 International Airport Center Blvd., 270... Individual), Caetano R. Lopes, Vice President, Application Type: Add NVO Service Eztrans Logistics Ltd. (NVO...
USDA-ARS?s Scientific Manuscript database
1. Regions of southern Florida, USA and southern Texas, USA (extending into Mexico)provide the source populations for virtually all fall armyworm infestations affecting the continental USA. Understanding how these overwintering populations annually disperse is important to efforts to predict and con...
International Symposium on Air Breathing Engines (5th)
1981-05-29
Marquardt Co., USA 22 Flowfield Studies of Dump Combustors Raghunath S. Boray, Wright Patterson AFB, USA and Cherng Chang, Breham Laboratory, USA 23 A Ramjet...Bending Loads R. Padmanabhan, K. Ramachandra, V. Maruthi and B.J. Raghunath , Gas Turbine Research Establishment, Bangalore, India 56 Influence of O-Rings
Distribution, hosts and identification of Meloidogyne partityla in the USA
USDA-ARS?s Scientific Manuscript database
Pecan, Carya illinoensis, is an economically important nut crop and member of the Juglandaceae native to the southern USA. Discovered in South Africa in 1986, Meloidogyne partityla was first found infecting pecan in USA in 1996 and currently occurs in Texas, New Mexico, Georgia, Arizona, Oklahoma a...
"USA Today": Can the Nation's Newspaper Survive?
ERIC Educational Resources Information Center
Wicks, Robert H.
The failure of 17 newspaper markets between 1957 and 1975 raises the question of whether the 1982 entrance of "USA Today" into the newspaper market demonstrated fiscal prudence. A 20-month advertising content analysis was conducted to assess advertising trends in "USA Today." These data were compared with industry statistics…
ERIC Educational Resources Information Center
Ames, Steve; And Others
Sections of the newspaper "USA Today" were compared with corresponding sections of four major newspapers--the "New York Times," the "Wall Street Journal," the "Los Angeles Herald Examiner," and the "Los Angeles Times"--to determine what editorial components made "USA Today" different and…
Pest status of the brown marmorated stink bug, Halyomorpha halys (Stal) in the USA
USDA-ARS?s Scientific Manuscript database
Since its initial discovery in Allentown, PA, USA, the brown marmorated stink bug (BMSB), Halyomorpha halys (Heteroptera: Pentatomidae), has now officially been detected in 37 states and the District of Columbia in the USA. Isolated populations also exist in Switzerland and Canada. This Asian spec...
78 FR 49546 - Importer of Controlled Substances; Notice of Application; Siegfried USA, LLC
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-14
... DEPARTMENT OF JUSTICE Drug Enforcement Administration Importer of Controlled Substances; Notice of Application; Siegfried USA, LLC This is notice that on June 10, 2013, Siegfried USA, LLC., 33 Industrial Park Road, Pennsville, New Jersey 08070, made application by letter to the Drug Enforcement Administration...
78 FR 46613 - Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-01
... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on June 10, 2013, Siegfried (USA), LLC., 33 Industrial Park Road...
78 FR 5500 - Manufacturer of Controlled Substances, Notice of Application; Siegfried (USA)
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-25
... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances, Notice of Application; Siegfried (USA) Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on June 19, 2012, Siegfried (USA), 33 Industrial Park Road, Pennsville...
78 FR 32458 - Manufacturer of Controlled Substances; Notice of Application; Siegfried USA, LLC
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-30
... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried USA, LLC Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on April 18, 2013, Siegfried USA, LLC., 33 Industrial Park Road...
31 CFR 537.529 - Exportation or reexportation of financial services to Burma authorized.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism (USA PATRIOT) Act of 2001 (Pub. L. 107-56) (USA PATRIOT Act) do not apply to the operation of correspondent accounts... the USA PATRIOT Act. See 31 CFR 1010.610(c). ...
77 FR 70825 - Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-27
... DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC Pursuant to Sec. 1301.33(a), Title 21 of the Code of Federal Regulations (CFR), this is notice that on November 5, 2012, Siegfried (USA) LLC, 33 Industrial Park Road...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-03
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,503] Compass Group USA, Inc... Services provided services (janitorial, maintenance, and hazardous waste disposal) that were directly... workers cannot be considered employees of Electrolux, but only of the subject firm, Compass Group USA...
2003-09-04
KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, while Greg Harlow, with United Space Alliance (USA) (above) threads a camera under the tiles of the orbiter Endeavour, Peggy Ritchie, USA, (behind the stand) and NASA’s Richard Parker (seated) watch the images on a monitor to inspect for corrosion.
2003-09-04
KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, while Greg Harlow, with United Space Alliance (USA), (above) threads a camera under the tiles of the orbiter Endeavour, NASA’s Richard Parker (below left) and Peggy Ritchie, with USA, (at right) watch the images on a monitor to inspect for corrosion.
2003-09-04
KENNEDY SPACE CENTER, FLA. - In the Orbiter Processing Facility, while Greg Harlow, with United Space Alliance (USA), (above) threads a camera under the tiles of the orbiter Endeavour, Peggy Ritchie, with USA, (behind the stand) and NASA’s Richard Parker watch the images on a monitor to inspect for corrosion.
Pricing behavior of USA exporter in wheat international market
NASA Astrophysics Data System (ADS)
Wibowo, R. P.; Sumono; Iddrisu, Y.; Darus, M.; Sihombing, L. P.; Jufri
2018-02-01
The number of wheat producing countries is changing over time. It is expected the change in wheat supply will lead world wheat market become more competitive and reduce market power of major exporter country. This paper tries to identify and examined the degree of market power on wheat international market for USA by using the Pricing to Market (PTM) method. USA is the biggest producer and exporter in wheat market. The PTM method found that USA impose noncompetitive strategy by applying price discrimination and apply market power to their importer country.
Summary of ARI Research on Remotely Monitored Sensors
1980-07-01
I NAVY PFRSONNEL R AND 0 CENTER/ I US ARMY AVN ENbINEERING FLIGHT ACTIVIIY ATTN8 SAVTE- TD SoFc OF NAVAL RESEARCH PERSONNEL AND TRAINING RESEARCH...LABS ATTN: LTL- TD -S I USA MORILITY EWUIPMENT R AND 0 COMO ATTNS ODMUE-TO I NIGHT VISION LAH ATTN: UHSEL-NV-SUU I USA TRAINING BUAHD I USA HUMAN...I PURDUE UNIV DLPT OF PSYCMOLOGICAL SCIE.NCES 1 05A MOHILITY EWI,1PMENT w AND 0 LUMMANL) ATTNt URDME-1rG IHQ . USA MDW ATTN; ANPE-vE It D A US ARMY
Larsen, Anders Rhod; Goering, Richard; Stegger, Marc; Lindsay, Jodi A.; Gould, Katherine A.; Hinds, Jason; Sørum, Marit; Westh, Henrik; Boye, Kit; Skov, Robert
2009-01-01
Analysis of methicillin-resistant Staphylococcus aureus (MRSA) characterized as USA300 by pulsed-field gel electrophoresis identified two distinct clones. One was similar to community-associated USA300 MRSA (ST8-IVa, t008, and Panton-Valentine leukocidin positive). The second (ST8-IVa, t024, and PVL negative) had different molecular characteristics and epidemiology, suggesting independent evolution. We recommend spa typing and/or PCR to discriminate between the two clones. PMID:19759225
International Program and Local Organizing Committees
NASA Astrophysics Data System (ADS)
2012-12-01
International Program Committee Dionisio Bermejo (Spain) Roman Ciurylo (Poland) Elisabeth Dalimier (France) Alexander Devdariani (Russia) Milan S Dimitrijevic (Serbia) Robert Gamache (USA) Marco A Gigosos (Spain) Motoshi Goto (Japan) Magnus Gustafsson (Sweden) Jean-Michel Hartmann (France) Carlos Iglesias (USA) John Kielkopf (USA) John C Lewis (Canada) Valery Lisitsa (Russia) Eugene Oks (USA) Christian G Parigger (USA) Gillian Peach (UK) Adriana Predoi-Cross (Canada) Roland Stamm (Germany) Local Organizing Committee Nikolay G Skvortsov (Chair, St Petersburg State University) Evgenii B Aleksandrov (Ioffe Physico-Technical Institute, St Petersburg) Vadim A Alekseev (Scientific Secretary, St Petersburg State University) Sergey F Boureiko (St.Petersburg State University) Yury N Gnedin (Pulkovo Observatory, St Petersburg) Alexander Z Devdariani (Deputy Chair, St Petersburg State University) Alexander P Kouzov (Deputy Chair, St Petersburg State University) Nikolay A Timofeev (St Petersburg State University)
Comparing perceptions of dental aesthetics in the USA with those in eleven ethnic groups.
Cons, N C; Jenny, J
1994-12-01
The Standard DAI is an orthodontic index based on perceptions of dental aesthetics in the USA. The Standard DAI is a regression equation linking perceptions of the social acceptability of dental aesthetics with the objective intraoral measurements of ten occlusal traits. Since the Standard DAI is based on perceptions of dental aesthetics in the USA it can be used without modification only where perceptions of dental aesthetics are similar to those in the USA. This study was designed to determine whether perceptions of dental aesthetics of students in eleven diverse ethnic groups are similar to those of students in the USA. The same 25 stimuli (photographs of dental configurations, a subset of the 200 stimuli used in deriving the Standard DAI equation) were rated for dental aesthetics by Australian, Chinese, German, Japanese, Korean, Latvian, Native American, Singaporean Chinese, Singaporean Indian, Singaporean Malay, and Thai students. Their ratings were compared with the ratings of the same 25 stimuli by students in the USA. Spearman rank-order correlations ranged from 0.84 to 0.94. These correlations are sufficiently high to show that perceptions of dental aesthetics in all eleven ethnic groups are very similar to the perceptions of USA students. Therefore the Standard DAI can be used without modification in all eleven ethnic groups.
Comparing perceptions of dental aesthetics in the USA with those in eleven ethnic groups.
Cons, N C; Jenny, J
1994-10-01
The Standard DAI is an orthodontic index based on perceptions of dental aesthetics in the USA. The Standard DAI is a regression equation linking perceptions of the social acceptability of dental aesthetics with the objective intraoral measurements of ten occlusal traits. Since the Standard DAI is based on perceptions of dental aesthetics in the USA it can be used without modification only where perceptions of dental aesthetics are similar to those in the USA. This study was designed to determine whether perceptions of dental aesthetics of students in eleven diverse ethnic groups are similar to those of students in the USA. The same 25 stimuli (photographs of dental configurations, a subset of the 200 stimuli used in deriving the Standard DAI equation) were rated for dental aesthetics by Australian, Chinese, German, Japanese, Korean, Latvian, Native American, Singaporean Chinese, Singaporean Indian, Singaporean Malay, and Thai students. Their ratings were compared with the ratings of the same 25 stimuli by students in the USA. Spearman rank-order correlations ranged from 0.84 to 0.94. These correlations are sufficiently high to show that perceptions of dental aesthetics in all eleven ethnic groups are very similar to the perceptions of USA students. Therefore the Standard DAI can be used without modification in all eleven ethnic groups.
Incremental Aerodynamic Coefficient Database for the USA2
NASA Technical Reports Server (NTRS)
Richardson, Annie Catherine
2016-01-01
In March through May of 2016, a wind tunnel test was conducted by the Aerosciences Branch (EV33) to visually study the unsteady aerodynamic behavior over multiple transition geometries for the Universal Stage Adapter 2 (USA2) in the MSFC Aerodynamic Research Facility's Trisonic Wind Tunnel (TWT). The purpose of the test was to make a qualitative comparison of the transonic flow field in order to provide a recommended minimum transition radius for manufacturing. Additionally, 6 Degree of Freedom force and moment data for each configuration tested was acquired in order to determine the geometric effects on the longitudinal aerodynamic coefficients (Normal Force, Axial Force, and Pitching Moment). In order to make a quantitative comparison of the aerodynamic effects of the USA2 transition geometry, the aerodynamic coefficient data collected during the test was parsed and incorporated into a database for each USA2 configuration tested. An incremental aerodynamic coefficient database was then developed using the generated databases for each USA2 geometry as a function of Mach number and angle of attack. The final USA2 coefficient increments will be applied to the aerodynamic coefficients of the baseline geometry to adjust the Space Launch System (SLS) integrated launch vehicle force and moment database based on the transition geometry of the USA2.
Carter, Brittany U; Kaylor, Mary Beth
2016-04-01
Hypertension is the most commonly diagnosed medical condition in the USA. Unfortunately, patients are misdiagnosed in primary care because of inaccurate office-based blood pressure measurements. Several US healthcare organizations currently recommend confirming an office-based hypertension diagnosis with ambulatory blood pressure monitoring to avoid overtreatment; however, its use for the purpose of confirming an office-based hypertension diagnosis is relatively unknown. This descriptive study surveyed 143 primary-care physicians in Oregon with regard to their current use of ambulatory blood pressure monitoring. Nineteen percent of the physicians reported that they would use ambulatory blood pressure monitoring to confirm an office-based hypertension diagnosis, although over half had never ordered it. The most frequent indication for ordering ambulatory blood pressure monitoring was to investigate suspected white-coat hypertension (37.3%). In addition, many of the practices did not own an ambulatory blood pressure monitoring device (79.7%) and, therefore, had to refer patients to other clinics or departments for testing. Many primary-care physicians will need to change their current clinical practice to align with the shift toward a confirmation process for office-based hypertension diagnoses to improve population health.
The Pfam protein families database.
Punta, Marco; Coggill, Penny C; Eberhardt, Ruth Y; Mistry, Jaina; Tate, John; Boursnell, Chris; Pang, Ningze; Forslund, Kristoffer; Ceric, Goran; Clements, Jody; Heger, Andreas; Holm, Liisa; Sonnhammer, Erik L L; Eddy, Sean R; Bateman, Alex; Finn, Robert D
2012-01-01
Pfam is a widely used database of protein families, currently containing more than 13,000 manually curated protein families as of release 26.0. Pfam is available via servers in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/). Here, we report on changes that have occurred since our 2010 NAR paper (release 24.0). Over the last 2 years, we have generated 1840 new families and increased coverage of the UniProt Knowledgebase (UniProtKB) to nearly 80%. Notably, we have taken the step of opening up the annotation of our families to the Wikipedia community, by linking Pfam families to relevant Wikipedia pages and encouraging the Pfam and Wikipedia communities to improve and expand those pages. We continue to improve the Pfam website and add new visualizations, such as the 'sunburst' representation of taxonomic distribution of families. In this work we additionally address two topics that will be of particular interest to the Pfam community. First, we explain the definition and use of family-specific, manually curated gathering thresholds. Second, we discuss some of the features of domains of unknown function (also known as DUFs), which constitute a rapidly growing class of families within Pfam.
Carroll, James M.; Krementz, David G.
2014-01-01
Wilson's snipe Gallinago delicata is one of the least studied North American game birds, and information on snipe populations and abundance is mostly unknown. We conducted roadside surveys stratified at the township level in the lower Mississippi Alluvial Valley (LMAV) in Arkansas, Mississippi and Louisiana, as well as the Red River Region, and the Gulf Coastal Plain of Louisiana during winters of 2009 and 2010. We identified observer, vegetation cover, and water cover as important covariates in estimating snipe densities. We detected 2915 snipe along 814 line transects (1450 km) for 2009 and 2010 combined. We estimated snipe densities of 8.05 individuals km-2 (95% CI: 4.57-14.17) in 2009, and 2.13 individuals km-2 (95% CI: 1.47-3.08) in 2010. We used the resulting snipe density estimates within the study area to calculate abundance estimates of 1 026 431 (95% CI: 582 707-1 806 774) in 2009, and 271 590 (95% CI: 187 435-392 722) in 2010 for the LMAV. Our data indicate that a road transect survey method is effective for estimating wintering snipe density and abundance in the lower Mississippi Flyway.
Lukban, James C.; Beyer, Roger D.; Moore, Robert D.
2012-01-01
Introduction and Hypothesis. We sought to determine the mesh extrusion (vaginal exposure) rates and subject outcomes following IntePro (Type I polypropylene) mesh “kit” repairs for vaginal prolapse. Methods. Data were pooled from two prospective multicenter studies evaluating the safety and efficacy of the Perigee and Apogee (American Medical Systems, Minnetonka, Minn, USA) to treat anterior and posterior/apical prolapses, respectively. Extrusions involving the anterior compartment (AC) or posterior compartment/apex (PC/A) were recorded. Results. Two hundred sixty women underwent mesh placement, with a total of 368 mesh units inserted (173 in the AC and 195 in the PC/A). Extrusions were noted in 13 (7.5%) of AC implants and 27 (13.8%) of PC/A implants through 12 months. No difference was seen between those with and without extrusion in regard to anatomic cure, postoperative painor quality of life at 1 year. Conclusions. Extrusion had no apparent effect on short-term outcomes. Given the unknown long-term sequellae of vaginal mesh exposure, a thorough assessment of risks and benefits of transvaginal mesh placement should be considered at the time of preoperative planning. PMID:22190952
Development of partial rock veneers by root throw in a subalpine setting
Osterkamp, W.R.; Toy, T.J.; Lenart, M.T.
2006-01-01
Rock veneers stabilize hillslope surfaces, occur especially in areas of immature soil, and form through a variety of process sets that includes root throw. Near Westcliffe, Colorado, USA, data were collected from a 20 ?? 500 m transect on the east slope of the Sangre de Cristo Mountains. Ages of pit/mound complexes with rock fragments exposed at the surface by root throw ranged from recent (freshly toppled tree) to unknown (complete tree decay). Calculations based on dimensions of the pit/mound complexes, estimated time of free topppling, sizes of exposed rock fragments, and percentage rock covers at pit/mound complexes, as well as within the transect area, indicate that recent rates of root throw have resulted in only partial rock veneering since late Pleistocene deglaciation. Weathering of rock fragments prevent development of an extensive rock veneer and causes a balance, achieved within an estimated 700 years, between the rates of rock-fragment exposure by root throw and clast disintegration by chemical reduction. The estimated rate of rock-fragment reduction accounts for part of the fluvial sediment yields observed for forested subalpine areas of western North America. Copyright ?? 2005 John Wiley & Sons, Ltd.
The analysis of a World War I U.S. service member's dental remains recovered in France.
Shiroma, Calvin Y
2014-11-01
In October 2009, the grave of an unknown World War I (WWI) U.S. service member was exhumed in Rembercourt-Sur-Mad Village, in the Lorraine Region of France. The skeletal remains and material evidence were accessioned into the Joint POW/MIA Accounting Command's (JPAC) Central Identification Laboratory (CIL). The personnel records for the associated casualty were requested, received, and reviewed. A dental profile was present among the service member's personal information. There were multiple points of concordance between the dental records of the associated casualty, and the recovered dental remains to include eight restored teeth, 15 unrestored teeth, and three antemortem missing teeth. Distinctive restorations which compared favorably included a porcelain crown and multiple gold foil fillings. All lines of evidence (historical, material evidence/personal effects, anthropological, and dental) and the circumstances of loss compared positively with the associated casualty. On April 1, 2010, the previously unaccounted-for U.S. service member was positively identified and on June 23, 2010, was buried with full military honors at Arlington National Cemetery. Published 2014. This article is a U.S. Government work and is in the public domain in the U.S.A.
NASA Astrophysics Data System (ADS)
Zhou, Wei-Xing; Sornette, Didier
2003-12-01
We propose a straightforward extension of our previously proposed log-periodic power-law model of the “anti-bubble” regime of the USA stock market since the summer of 2000, in terms of the renormalization group framework to model critical points. Using a previous work by Gluzman and Sornette (Phys. Rev. E 65 (2003) 036142) on the classification of the class of Weierstrass-like functions, we show that the five crashes that occurred since August 2000 can be accurately modeled by this approach, in a fully consistent way with no additional parameters. Our theory suggests an overall consistent organization of the investors forming a collective network which interact to form the pessimistic bearish “anti-bubble” regime with intermittent acceleration of the positive feedbacks of pessimistic sentiment leading to these crashes. We develop retrospective predictions, that confirm the existence of significant arbitrage opportunities for a trader using our model. Finally, we offer a prediction for the unknown future of the US S&P500 index extending over 2003 and 2004, that refines the previous prediction of Sornette and Zhou (Quant. Finance 2 (2002) 468).
Pseudotachylyte increases the post-slip strength of faults
Proctor, Brooks; Lockner, David A.
2016-01-01
Solidified frictional melts, or pseudotachylytes, are observed in exhumed faults from across the seismogenic zone. These unique fault rocks, and many experimental studies, suggest that frictional melting can be an important process during earthquakes. However, it remains unknown how melting affects the post-slip strength of the fault and why many exhumed faults do not contain pseudotachylyte. Analyses of triaxial stick-slip events on Westerly Granite (Rhode Island, USA) sawcuts at confining pressures from 50 to 400 MPa show evidence for frictional heating, including some events energetic enough to generate surface melt. Total and partial stress drops were observed with slip as high as 6.5 mm. We find that in dry samples following melt-producing stick slip, the shear failure strength increased as much as 50 MPa, while wet samples had <10 MPa strengthening. Microstructural analysis indicates that the strengthening is caused by welding of the slip surface during melt quenching, suggesting that natural pseudotachylytes may also strengthen faults after earthquakes. These results predict that natural pseudotachylyte will inhibit slip reactivation and possibly generate stress heterogeneities along faults. Wet samples do not exhibit melt welding, possibly because of thermal pressurization of water reducing frictional heating during slip.
Biological relevance of streamflow metrics: Regional and national perspectives
Carlisle, Daren M.; Grantham, Theodore E.; Eng, Kenny; Wolock, David M.
2017-01-01
Protecting the health of streams and rivers requires identifying ecologically significant attributes of the natural flow regime. Streamflow regimes are routinely quantified using a plethora of hydrologic metrics (HMs), most of which have unknown relevance to biological communities. At regional and national scales, we evaluated which of 509 commonly used HMs were associated with biological indicators of fish and invertebrate community integrity. We quantified alteration of each HM by using statistical models to predict site-specific natural baseline values for each of 728 sites across the USA where streamflow monitoring data were available concurrent with assessments of invertebrate or fish community integrity. We then ranked HMs according to their individual association with biological integrity based on random forest models that included HMs and other relevant covariates, such as land cover and stream chemistry. HMs were generally the most important predictors of biological integrity relative to the covariates. At a national scale, the most influential HMs were measures of depleted high flows, homogenization of flows, and erratic flows. Unique combinations of biologically relevant HMs were apparent among regions. We discuss the implications of our findings to the challenge of selecting HMs for streamflow research and management.
Cutaneous and renal glomerular vasculopathy as a cause of acute kidney injury in dogs in the UK
Hawkins, I.; Robin, C.; Newton, R. J.; Jepson, R.; Stanzani, G.; McMahon, L. A.; Pesavento, P.; Carr, T.; Cogan, T.; Couto, C. G.; Cianciolo, R.; Walker, D. J.
2015-01-01
To describe the signalment, clinicopathological findings and outcome in dogs presenting with acute kidney injury (AKI) and skin lesions between November 2012 and March 2014, in whom cutaneous and renal glomerular vasculopathy (CRGV) was suspected and renal thrombotic microangiopathy (TMA) was histopathologically confirmed. The medical records of dogs with skin lesions and AKI, with histopathologically confirmed renal TMA, were retrospectively reviewed. Thirty dogs from across the UK were identified with clinicopathological findings compatible with CRGV. These findings included the following: skin lesions, predominantly affecting the distal extremities; AKI; and variably, anaemia, thrombocytopaenia and hyperbilirubinaemia. Known causes of AKI were excluded. The major renal histopathogical finding was TMA. All thirty dogs died or were euthanised. Shiga toxin was not identified in the kidneys of affected dogs. Escherichia coli genes encoding shiga toxin were not identified in faeces from affected dogs. CRGV has previously been reported in greyhounds in the USA, a greyhound in the UK, without renal involvement, and a Great Dane in Germany. This is the first report of a series of non-greyhound dogs with CRGV and AKI in the UK. CRGV is a disease of unknown aetiology carrying a poor prognosis when azotaemia develops. PMID:25802439
Sabo, John L.
2016-01-01
Despite the clear importance of water balance to the evolution of terrestrial life, much remains unknown about the effects of animal water balance on food webs. Based on recent research suggesting animal water imbalance can increase trophic interaction strengths in cages, we hypothesized that water availability could drive top-down effects in open environments, influencing the occurrence of trophic cascades. We manipulated large spider abundance and water availability in 20 × 20 m open-air plots in a streamside forest in Arizona, USA, and measured changes in cricket and small spider abundance and leaf damage. As expected, large spiders reduced both cricket abundance and herbivory under ambient, dry conditions, but not where free water was added. When water was added (free or within moist leaves), cricket abundance was unaffected by large spiders, but spiders still altered herbivory, suggesting behavioural effects. Moreover, we found threshold-type increases in herbivory at moderately low soil moisture (between 5.5% and 7% by volume), suggesting the possibility that water balance may commonly influence top-down effects. Overall, our results point towards animal water balance as an important driver of direct and indirect species interactions and food web dynamics in terrestrial ecosystems. PMID:27534953
Bown, T.M.; Kraus, M.J.
1983-01-01
The ichnofossil assemblage of the lower Eocene Willwood Formation consists of at least nine distinct endichnia that are preserved in full relief. Four forms (three ichnogenera and four ichnospecies) are new and represent fodinichnia and domichnia of oligochaete worms, an insect or spider, an unknown vertebrate (probably a mammal), and domichnia of an unidentified organism. Other potential trace makers of the ichnofauna include insects, mollusks, and decapods. In contrast to an Egyptian Oligocene fluvial ichnofauna produced largely by animals that burrowed in stream channel deposits, the Willwood assemblage is principally of flood-plain origin. Though the ichnofauna occurs in a variety of paleosol types, most of the fossils are restricted in distribution to specific sediment and soil types and, within paleosols, to specific identifiable horizons. This attribute will make them valuable indiced of paleoenvironment once they are better known in other ancient alluvial sequences. The environment suggested by the Willwood trace fossils (damp, but not wet soils with fluctuating water tables) is consistent with the warm temperate to subtropical (possibly monsoonal) conditions that are interpreted for the Willwood Formation by independent evidence of body fossils and paleopedology. ?? 1983.
Maidment, Susannah Catherine Rose; Brassey, Charlotte; Barrett, Paul Michael
2015-01-01
Although Stegosaurus is one of the most iconic dinosaurs, well-preserved fossils are rare and as a consequence there is still much that remains unknown about the taxon. A new, exceptionally complete individual affords the opportunity to describe the anatomy of Stegosaurus in detail for the first time in over a century, and enables additional comparisons with other stegosaurian dinosaurs. The new specimen is from the Red Canyon Ranch Quarry, near Shell Wyoming, and appears to have been so well preserved because it was buried rapidly in a pond or body of standing water immediately after death. The quarry is probably located in the middle part of the Morrison Formation, which is believed to be Tithonian in age in this area. The specimen is referable to Stegosaurus stenops based on the possession of an edentulous anterior portion of the dentary and elevated postzygapophyses on the cervical vertebrae. New information provided by the specimen concerns the morphology of the vertebrae, the iliosacral block and dermal armor. Several aspects of its morphology indicate the individual was not fully skeletally mature at the time of death, corroborating a previous histological study.
[Social Networks of Children with Mentally Ill Parents].
Stiawa, Maja; Kilian, Reinhold
2017-10-01
Social Networks of Children with Mentally Ill Parents Mental illness of parents can be a load situation for children. Supporting social relations might be an important source in such a situation. Social relations can be shown by social network analysis. Studies about social networks and mental health indicate differences regarding structure and potential for support when compared with social networks of healthy individuals. If and how mental illness of parents has an impact on their children's network is widely unknown. This systematic review shows methods and results of studies about social networks of children with mentally ill parents. By systematic search in electronic databases as well as manual search, two studies were found who met the target criteria. Both studies were conducted in the USA. Results of studies indicate that parental mental illness affects the state of mental health and social networks of children. Symptomatology of children changed due to perceived social support of network contacts. Impact of social support and strong network contacts seems to depend on age of children and the family situation. That's why support offers should be adapt to children's age. Focusing on social networks as potential resource for support and needs of the family affected seems appropriate during treatment.
Shiroma, Calvin Y
2016-01-01
During the Korean War, the Office of the Quartermaster General's Graves Registration Service (GRS) was responsible for the recovery, processing, identification, and repatriation of US remains. In January 1951, the GRS established a Central Identification Unit (CIU) at Kokura, Japan. At the Kokura CIU, postmortem dental examinations were performed by the dental technicians. Thirty-nine postmortem dental examinations performed at the CIU were compared to the findings documented in the Forensic Odontology Reports written at the JPAC Central Identification Laboratory (CIL). Differences were noted in 20 comparisons (51%). The majority of the discrepancies was considered negligible and would not alter the JPAC decision to disinter a set of unknown remains. Charting discrepancies that were considered significant included the occasional failure of the Kokura technicians to identify teeth with inter-proximal or esthetic restorations and the misidentification of a mechanically prepared tooth (i.e., tooth prepared for a restoration) as a carious surface. Published 2015. This article is a U.S. Government work and is in the public domain in the USA.
2010-01-01
Background People often search for information on influenza A(H1N1)v prevention on the web. The extent to which information found on the Internet is consistent with recommendations issued by the World Health Organization is unknown. Methods We conducted a search for "swine flu" accessing 3 of the most popular search engines through different proxy servers located in 4 English-speaking countries (Australia, Canada, UK, USA). We explored each site resulting from the searches, up to 4 clicks starting from the search engine page, analyzing availability of World Health Organization recommendations for swine flu prevention. Results Information on hand cleaning was reported on 79% of the 147 websites analyzed; staying home when sick was reported on 77.5% of the websites; disposing tissues after sneezing on 75.5% of the websites. Availability of other recommendations was lower. The probability of finding preventative recommendations consistent with World Health Organization varied by country, type of website, and search engine. Conclusions Despite media coverage on H1N1 influenza, relevant information for prevention is not easily found on the web. Strategies to improve information delivery to the general public through this channel should be improved. PMID:20854690
Gesualdo, Francesco; Romano, Mariateresa; Pandolfi, Elisabetta; Rizzo, Caterina; Ravà, Lucilla; Lucente, Daniela; Tozzi, Alberto E
2010-09-20
People often search for information on influenza A(H1N1)v prevention on the web. The extent to which information found on the Internet is consistent with recommendations issued by the World Health Organization is unknown. We conducted a search for "swine flu" accessing 3 of the most popular search engines through different proxy servers located in 4 English-speaking countries (Australia, Canada, UK, USA). We explored each site resulting from the searches, up to 4 clicks starting from the search engine page, analyzing availability of World Health Organization recommendations for swine flu prevention. Information on hand cleaning was reported on 79% of the 147 websites analyzed; staying home when sick was reported on 77.5% of the websites; disposing tissues after sneezing on 75.5% of the websites. Availability of other recommendations was lower. The probability of finding preventative recommendations consistent with World Health Organization varied by country, type of website, and search engine. Despite media coverage on H1N1 influenza, relevant information for prevention is not easily found on the web. Strategies to improve information delivery to the general public through this channel should be improved.
A two-step real-time PCR assay for quantitation and genotyping of human parvovirus 4.
Väisänen, E; Lahtinen, A; Eis-Hübinger, A M; Lappalainen, M; Hedman, K; Söderlund-Venermo, M
2014-01-01
Human parvovirus 4 (PARV4) of the family Parvoviridae was discovered in a plasma sample of a patient with an undiagnosed acute infection in 2005. Currently, three PARV4 genotypes have been identified, however, with an unknown clinical significance. Interestingly, these genotypes seem to differ in epidemiology. In Northern Europe, USA and Asia, genotypes 1 and 2 have been found to occur mainly in persons with a history of injecting drug use or other parenteral exposure. In contrast, genotype 3 appears to be endemic in sub-Saharan Africa, where it infects children and adults without such risk behaviour. In this study, a novel straightforward and cost-efficient molecular assay for both quantitation and genotyping of PARV4 DNA was developed. The two-step method first applies a single-probe pan-PARV4 qPCR for screening and quantitation of this relatively rare virus, and subsequently, only the positive samples undergo a real-time PCR-based multi-probe genotyping. The new qPCR-GT method is highly sensitive and specific regardless of the genotype, and thus being suitable for studying the clinical impact and occurrence of the different PARV4 genotypes. Copyright © 2013 Elsevier B.V. All rights reserved.
Shiroma, Calvin Y
2016-01-01
As of August 2014, the Joint POW/MIA Accounting Command has identified the remains of 1980 previously unknown U.S. service members; 280 were from the Korean War. To determine the accuracy and completeness of the available antemortem (AM) dental records, a review of the AM/postmortem (AM/PM) dental record comparisons from 233 Forensic Odontology Reports written in support of remains identified from the Korean War was performed. Seventy-two AM/PM comparisons resulted in exact dental chartings while 161 contained discrepancies which were explainable. Explainable discrepancies include undocumented treatment (103), incorrectly charted third molars as missing (82), differing opinions of specific molars present/missing (20), and erroneous treatment documentation and/or misidentification of teeth present/missing (22, other than molars). Reassessment has revealed varying levels of completeness for our available AM dental records, the need to thoroughly review our computerized comparisons, adjust our comparisons to include molar pattern variations/third molars, and updating our database comparison program. Published 2015. This article is a U.S. Government work and is in the public domain in the U.S.A.
The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication.
Zhang, Yi; Chen, Yong; Gucek, Marjan; Xu, Hong
2016-05-17
Early embryonic development features rapid nuclear DNA replication cycles, but lacks mtDNA replication. To meet the high-energy demands of embryogenesis, mature oocytes are furnished with vast amounts of mitochondria and mtDNA However, the cellular machinery driving massive mtDNA replication in ovaries remains unknown. Here, we describe a Drosophila AKAP protein, MDI that recruits a translation stimulator, La-related protein (Larp), to the mitochondrial outer membrane in ovaries. The MDI-Larp complex promotes the synthesis of a subset of nuclear-encoded mitochondrial proteins by cytosolic ribosomes on the mitochondrial surface. MDI-Larp's targets include mtDNA replication factors, mitochondrial ribosomal proteins, and electron-transport chain subunits. Lack of MDI abolishes mtDNA replication in ovaries, which leads to mtDNA deficiency in mature eggs. Targeting Larp to the mitochondrial outer membrane independently of MDI restores local protein synthesis and rescues the phenotypes of mdi mutant flies. Our work suggests that a selective translational boost by the MDI-Larp complex on the outer mitochondrial membrane might be essential for mtDNA replication and mitochondrial biogenesis during oogenesis. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.
Long-distance electron transport occurs globally in marine sediments
NASA Astrophysics Data System (ADS)
Burdorf, Laurine D. W.; Tramper, Anton; Seitaj, Dorina; Meire, Lorenz; Hidalgo-Martinez, Silvia; Zetsche, Eva-Maria; Boschker, Henricus T. S.; Meysman, Filip J. R.
2017-02-01
Recently, long filamentous bacteria have been reported conducting electrons over centimetre distances in marine sediments. These so-called cable bacteria perform an electrogenic form of sulfur oxidation, whereby long-distance electron transport links sulfide oxidation in deeper sediment horizons to oxygen reduction in the upper millimetres of the sediment. Electrogenic sulfur oxidation exerts a strong impact on the local sediment biogeochemistry, but it is currently unknown how prevalent the process is within the seafloor. Here we provide a state-of-the-art assessment of its global distribution by combining new field observations with previous reports from the literature. This synthesis demonstrates that electrogenic sulfur oxidation, and hence microbial long-distance electron transport, is a widespread phenomenon in the present-day seafloor. The process is found in coastal sediments within different climate zones (off the Netherlands, Greenland, the USA, Australia) and thrives on a range of different coastal habitats (estuaries, salt marshes, mangroves, coastal hypoxic basins, intertidal flats). The combination of a widespread occurrence and a strong local geochemical imprint suggests that electrogenic sulfur oxidation could be an important, and hitherto overlooked, component of the marine cycle of carbon, sulfur and other elements.
Mars Express scientists find a different Mars underneath the surface
NASA Astrophysics Data System (ADS)
2006-12-01
Observations by MARSIS, the first subsurface sounding radar used to explore a planet, strongly suggest that ancient impact craters lie buried beneath the smooth, low plains of Mars' northern hemisphere. The technique uses echoes of radio waves that have penetrated below the surface. MARSIS found evidence that these buried impact craters - ranging from about 130 to 470 kilometres in diameter - are present under much of the northern lowlands. The findings appear in the 14 December 2006 issue of the journal Nature. With MARSIS "it's almost like having X-ray vision," said Thomas R. Watters of the National Air and Space Museum's Center for Earth and Planetary Studies, Washington, and lead author of the results. "Besides finding previously unknown impact basins, we've also confirmed that some subtle, roughly circular, topographic depressions in the lowlands are related to impact features." Studies of how Mars evolved help in understanding early Earth. Some signs of the forces at work a few thousand million years ago are harder to detect on Earth because many of them have been obliterated by tectonic activity and erosion. The new findings bring planetary scientists closer to understanding one of the most enduring mysteries about the geological evolution and history of Mars. In contrast to Earth, Mars shows a striking difference between its northern and southern hemispheres. Almost the entire southern hemisphere has rough, heavily cratered highlands, while most of the northern hemisphere is smoother and lower in elevation. Since the impacts that cause craters can happen anywhere on a planet, the areas with fewer craters are generally interpreted as younger surfaces where geological processes have erased the impact scars. The surface of Mars' northern plains is young and smooth, covered by vast amounts of volcanic lava and sediment. However, the new MARSIS data indicate that the underlying crust is extremely old. “The number of buried impact craters larger than 200 kilometres in diameter that we have found with MARSIS,” said Jeffrey Plaut, MARSIS co-Principal Investigator, from the Jet Propulsion Laboratory, California, “tells us that the underlying crust in the northern lowlands must be very ancient, dating to the Early Noachian epoch (lasting from the planet's birth to about 4 thousand million years ago).” The Early Noachian was an era in which impact cratering was very intense across the Solar System. The results suggest that the crust of the northern lowlands is as old as the oldest exposed southern highlands, also dated to the Noachian epoch, and that the dichotomy between northern and southern hemispheres probably formed very early in the history of Mars. “These results are truly interesting and unprecedented,” added Giovanni Picardi. “MARSIS can contribute to understanding of the geology of Mars through analysis of the surface and subsurface morphology. In addition, from detailed analysis of the instrument’s data, we can obtain valuable information about the composition of the materials.” Note to editors The findings appear in the 14 December 2006 issue of the journal Nature, in the letter headed: “MARSIS radar sounder evidence of buried basins in the northern lowlands of Mars”, by T.R. Watters (National Air and Space Museum's Center for Earth and Planetary Studies, Washington, USA), C.J. Leuschen (Center for Remote Sensing of Ice-sheets, Univ. of Kansas, USA), J.J. Plaut, A. Safaenili and A.B. Ivanov (Jet Propulsion Laboratory, CA, USA), G. Picardi (Infocom Dept., Univ. of Rome ‘La Sapienza’, Italy), S.M. Clifford (Lunar and Planetary Institute, Texas, USA), W.M. Farrell (NASA/GSFC, Maryland, USA), R.J. Phillips (Dept. of Earth and Planetary Sciences, Washington Univ., Missouri, USA), and E.R. Stofan (Proxemy Research, Maryland, USA). The MARSIS instrument was developed in the framework of a Memorandum of Understanding between the Italian Space Agency (ASI) and NASA. It was developed by Alenia Spazio under ASI management and the scientific supervision of the University of Rome ‘La Sapienza’, in partnership with the Jet Propulsion Laboratory (JPL) in Pasadena, California, and the University of Iowa. It is the first instrument ever designed to actually look below the surface of Mars. The Italian-American MARSIS team is also largely involved in the SHARAD radar, a facility instrument provided by ASI for NASA’s Mars Reconnaissance Orbiter (MRO), launched on 12 August 2005. MARSIS and SHARAD are two radars designed to provide complementary information about the Martian subsurface. MARSIS can penetrate to depths of 5 kilometres or more, while SHARAD is probing layers closer to the surface down to 1 kilometre.
McDougal, Linda K.; Fosheim, Gregory E.; Nicholson, Ainsley; Bulens, Sandra N.; Limbago, Brandi M.; Shearer, Julia E. S.; Summers, Anne O.; Patel, Jean B.
2010-01-01
USA300 methicillin-resistant Staphylococcus aureus (MRSA) isolates are usually resistant only to oxacillin, erythromycin, and, increasingly, levofloxacin. Of these, oxacillin and levofloxacin resistances are chromosomally encoded. Plasmid-mediated clindamycin, mupirocin, and/or tetracycline resistance has been observed among USA300 isolates, but these descriptions were limited to specific patient populations or isolated occurrences. We examined the antimicrobial susceptibilities of invasive MRSA isolates from a national surveillance population in order to identify USA300 isolates with unusual, possibly emerging, plasmid-mediated antimicrobial resistance. DNA from these isolates was assayed for the presence of resistance determinants and the presence of a pSK41-like conjugative plasmid. Of 823 USA300 isolates, 72 (9%) were tetracycline resistant; 69 of these were doxycycline susceptible and tetK positive, and 3 were doxycycline resistant and tetM positive. Fifty-one (6.2%) isolates were clindamycin resistant and ermC positive; 22 (2.7%) isolates were high-level mupirocin resistant (mupA positive); 5 (0.6%) isolates were trimethoprim-sulfamethoxazole (TMP-SMZ) resistant, of which 4 were dfrA positive; and 7 (0.9%) isolates were gentamicin resistant and aac6′-aph2″ positive. Isolates with pSK41-like plasmids (n = 24) were positive for mupA (n = 19), dfrA (n = 6), aac6′-aph2″ (n = 6), tetM (n = 2), and ermC (n = 8); 20 pSK41-positive isolates were positive for two or more resistance genes. Conjugative transfer of resistance was demonstrated between four gentamicin- and mupirocin-resistant and three gentamicin- and TMP-SMZ-resistant USA300 isolates; transconjugants harbored a single pSK41-like plasmid, which was PCR positive for aac6′-aph2″ and either mupA and/or dfrA. USA300 and USA100 isolates from the same state with identical resistance profiles contained pSK41-like plasmids with indistinguishable restriction and Southern blot profiles, suggesting horizontal plasmid transfer between USA100 and USA300 isolates. PMID:20585117
Li, Feiming; Kalinowski, Kevin E; Song, Hao; Bates, Bruce P
2014-09-01
The relationship between the Comprehensive Osteopathic Medical Achievement Test (COMAT) series of subject examinations and the Comprehensive Osteopathic Medical Licensing Examination-USA Level 2-Cognitive Evaluation (COMLEX-USA Level 2-CE) has not been thoroughly examined. To investigate the factors associated with performance on COMAT subject examinations and how COMAT scores correlate with COMLEX-USA Level 2-CE scores. We examined scores of participants from 2 COMAT examination cycles in 2011 and 2012. According to surveys, most schools used COMAT scores in clerkship and clinical rotation evaluation, which were classified as being used for "high-stakes" purposes. We matched first-attempt COMAT scores with first-attempt COMLEX-USA Level 2-CE scores, and we conducted correlation analyses between the scores from the 7 COMAT subject examinations, as well as between COMAT and COMLEX-USA Level 2-CE scores. Multiple linear regression analyses were performed to investigate how much variance in COMLEX-USA Level 2-CE scores was explained by COMAT scores. In 2011 and 2012, respectively, 3751 and 3786 COMAT candidates had COMLEX-USA Level 2-CE scores (53.0% and 93.9%, respectively, had ⩾1 high-stakes COMAT score). Intercorrelations between COMAT scores were low to moderate (r=0.27-0.53), as hypothesized. Correlations between COMAT and Level 2-CE scores were moderate to high, with the highest correlations for internal medicine COMAT scores (r=0.63-0.65). All regressions showed internal medicine scores as the strongest predictor of Level 2-CE performance. Groups with high-stakes scores had larger adjusted coefficients of determination than those with low-stakes scores (eg, R(2)=0.63 vs 0.52, respectively, in 2011). For 2012 candidates with high-stakes scores, all predictors were statistically significant. The COMAT subject examination scores were moderately intercorrelated, as hypothesized, with higher correlations between COMAT and COMLEX-USA Level 2-CE scores. The COMAT performance was predictive of COMLEX-USA Level 2-CE performance. © 2014 The American Osteopathic Association.
Dixon, Donna
2015-04-01
Previous studies by the author showed differences in preadmission variables and Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) scores between women and men at the New York Institute of Technology College of Osteopathic Medicine (NYIT-COM). It is pertinent to reexamine the preadmission variables, medical school performance, and COMLEX-USA scores of women and men to determine whether these differences still exist. To examine the relationship between student sex and performance on COMLEX-USA Level 1 and Level 2-Cognitive Evaluation (CE), performance during medical school, and preadmission academic variables at NYIT-COM. Scores on COMLEX-USA Level 1 and COMLEX-USA Level 2-CE, grades in all courses taken during the first 2 years of medical school, the National Board of Osteopathic Medical Examiners' clinical science subject examination scores, Medical College Admission Test (MCAT) scores, and undergraduate grade point averages (GPAs) were compared between women and men in the classes graduating between 2009 and 2012. Data from 748 students were analyzed. Men had statistically significantly higher scores than women on COMLEX-USA Level 1 in 2009 (540 vs 500; P<.001) and 2010 (537 vs 496; P<.001). No statistically significant difference in COMLEX-USA Level 2-CE scores was found between women and men. The performance of women and men was comparable during the first 2 years of medical school and on clinical science subject examinations in years 3 and 4. Men had statistically significantly higher MCAT scores than women, but no statistically significant differences were found between women's and men's undergraduate GPAs. Men were found to have higher scores than women on COMLEX-USA Level 1 and the MCAT. However, the reasons behind these data have yet to be elucidated. Although a stronger background in basic science could explain the discrepancy in scores between women and men, women were found to have equally high science GPAs and performed comparably to men in osteopathic medical school. The results were in agreement with previous studies at NYIT-COM.
Predictors of scoring at least 600 on COMLEX-USA Level 1: successful preparation strategies.
Vora, Aditya; Maltezos, Nathan; Alfonzo, Lauren; Hernandez, Nilda; Calix, Erica; Fernandez, M Isabel
2013-02-01
Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) Level 1 scores are an important criterion used by residency directors to make residency placement decisions. To explore the association between scoring at least 600 on COMLEX-USA Level 1 and grade point average (GPA), scores on the Medical College Admission Test (MCAT), and different test preparation strategies. Third-year osteopathic medical students at Nova Southeastern University were invited to complete a self-administered survey regarding their COMLEX-USA preparation strategies and to provide consent for the researchers to access their preclinical GPA and their MCAT and COMLEX-USA scores. Descriptive analyses were conducted to understand examination preparation procedures and resources used, and bivariate analyses were conducted to identify the statisically significant predictors of scoring 600 or higher. Two separate logistic regressions were also run. The first included all of the statisically significant factors that emerged from the bivariate analyses, and the second examined which candidate predictors remained statistically significant once the effects of GPA and MCAT scores were removed. One hundred twenty-two students completed the survey, and 113 (93%) provided informed consent to access their preclinical GPA and their MCAT and COMLEX-USA scores. In the first regression, scoring 600 or higher was associated with a higher GPA (P<.02), a higher MCAT score (P<.05), earlier preparation initiation (P<.05), and not ranking the Comprehensive Osteopathic Medical Self-Assessment Examination (COMSAE) as the most helpful practice examination (P<.04). In the second regression, scoring 600 or higher was associated with earlier initiation of examination preparation (P<.01) and not ranking COMBANK (question bank for COMLEX-USA) as the most helpful question bank (P<.03). Among the different examination preparation methods, the specific resources ranked as most helpful were First Aid for the USMLE (United States Medical Licensing Examination) (review book), the COMSAE (practice examination); COMBANK (question bank); and Kaplan USMLE (lecture videos). Preclinical GPA and MCAT scores continue to be important predictors of scoring at least 600 on COMLEX-USA Level 1. However, the findings underscore the importance of maintaining a high GPA during the first 2 years of medical school and initiating COMLEX-USA preparation early.
Villaseñor-Sierra, Alberto; Katahira, Eva; Jaramillo-Valdivia, Abril N; Barajas-García, María de los Angeles; Bryant, Amy; Morfín-Otero, Rayo; Márquez-Díaz, Francisco; Tinoco, Juan Carlos; Sánchez-Corona, José; Stevens, Dennis L
2012-03-01
To compare the prevalence, phenotypes, and genes responsible for erythromycin resistance among Streptococcus pyogenes isolates from Mexico and the USA. Eighty-nine invasive and 378 non-invasive isolates from Mexico, plus 148 invasive, 21 non-invasive, and five unclassified isolates from the USA were studied. Susceptibilities to penicillin, erythromycin, clindamycin, ceftriaxone, and vancomycin were evaluated according to Clinical and Laboratory Standards Institute (CLSI) standards. Phenotypes of erythromycin resistance were identified by triple disk test, and screening for mefA, ermTR, and ermB genes was carried out by PCR. All isolates were susceptible to penicillin, ceftriaxone, and vancomycin. Erythromycin resistance was found in 4.9% of Mexican strains and 5.2% of USA strains. Phenotypes in Mexican strains were 95% M and 5% cMLS; in strains from the USA, phenotypes were 33.3% iMLS, 33.3% iMLS-D, and 33.3% M. Erythromycin resistance genes in strains from Mexico were mefA (95%) and ermB (5%); USA strains harbored ermTR (56%), mefA (33%), and none (11%). In Mexico, all erythromycin-resistant strains were non-invasive, whereas 89% of strains from the USA were invasive. Erythromycin resistance continues to exist at low levels in both Mexico and the USA, although the genetic mechanisms responsible differ between the two nations. These genetic differences may be related to the invasive character of the S. pyogenes isolated. Copyright © 2011 International Society for Infectious Diseases. All rights reserved.
Uhlemann, Anne-Catrin; Kennedy, Adam D.; Martens, Craig; Porcella, Stephen F.; DeLeo, Frank R.; Lowy, Franklin D.
2012-01-01
Staphylococcus aureus is a frequent cause of serious infections and also a human commensal. The emergence of community-associated methicillin-resistant S. aureus led to a dramatic increase in skin and soft tissue infections worldwide. This epidemic has been driven by a limited number of clones, such as USA300 in the United States. To better understand the extent of USA300 evolution and diversification within communities, we performed comparative whole-genome sequencing of three clinical and five colonizing USA300 isolates collected longitudinally from three unrelated households over a 15-month period. Phylogenetic analysis that incorporated additional geographically diverse USA300 isolates indicated that all but one likely arose from a common recent ancestor. Although limited genetic adaptation occurred over the study period, the greatest genetic heterogeneity occurred between isolates from different households and within one heavily colonized household. This diversity allowed for a more accurate tracking of interpersonal USA300 transmission. Sequencing of persisting USA300 isolates revealed mutations in genes involved in major aspects of S. aureus function: adhesion, cell wall biosynthesis, virulence, and carbohydrate metabolism. Genetic variations also included accumulation of multiple polymorphisms within select genes of two multigene operons, suggestive of small genome rearrangements rather than de novo single point mutations. Such rearrangements have been underappreciated in S. aureus and may represent novel means of strain variation. Subtle genetic changes may contribute to USA300 fitness and persistence. Elucidation of small genome rearrangements reveals a potentially new and intriguing mechanism of directed S. aureus genome diversification in environmental niches and during pathogen–host interactions. PMID:23104992
Post, Robert M; Leverich, Gabriele S; Kupka, Ralph; Keck, Paul E; McElroy, Susan L; Altshuler, Lori L; Frye, Mark A; Rowe, Michael; Grunze, Heinz; Suppes, Trisha; Nolen, Willem A
2015-10-01
We previously found that compared with Europe more parents of the USA patients were positive for a mood disorder, and that this was associated with early onset bipolar disorder. Here we examine family history of psychiatric illness in more detail across several generations. A total of 968 outpatients (average age 41) with bipolar disorder from four sites in the USA and three in the Netherlands and Germany (abbreviated as Europe) gave informed consent and provided detailed demographic and family history information on a patient questionnaire. Family history of psychiatric illness (bipolar disorder, unipolar depression, suicide attempt, alcohol abuse, substance abuse, and other illness) was collected for each parent, four grandparents, siblings, and children. Parents of the probands with bipolar disorder from the USA compared with Europe had a significantly higher incidence of both unipolar and bipolar mood disorders, as well as each of the other psychiatric conditions listed above. With a few exceptions, this burden of psychiatric disorders was also significantly greater in the grandparents, siblings, and children of the USA versus European patients. The increased complexity of psychiatric illness and its occurrence over several generations in the families of patients with bipolar disorder from the USA versus Europe could be contributing to the higher incidence of childhood onsets and greater virulence of illness in the USA compared with Europe. These data are convergent with others suggesting increased both genetic and environmental risk in the USA, but require replication in epidemiologically-derived populations with data based on interviews of the family members.
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2013-05-30
... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [S-32-2013] Approval of Subzone Status; Teva Pharmaceuticals USA, Inc.; North Wales, Chalfont, Kutztown and Sellersville, Pennsylvania On March 18, 2013, the... activation limit of FTZ 35, on behalf of Teva Pharmaceuticals USA, Inc., in North Wales, Chalfont, Kutztown...
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2010-09-01
... Authority; Foreign-Trade Zone 22; LG Electronics Mobilecomm USA, Inc. (Cell Phone Kitting and Distribution... authority on behalf of LG Electronics Mobilecomm USA, Inc. (LGEMU), within FTZ 22 in Bolingbrook, Illinois... application for manufacturing authority under zone procedures within FTZ 22 on behalf of LG Electronics...