The Role of the National Guard in Responding to Weapons of Mass Destruction (WMD) Attacks in the U.S.: Where Do We Stand?

DTIC Science & Technology

2001-04-01

the Graduation Requirements Advisor: Lieutenant Colonel Robin Nestor Maxwell Air Force Base, Alabama April 2001 Report Documentation Page Report...Number Task Number Work Unit Number Performing Organization Name(s) and Address(es) Air Command and Staff College Air University Maxwell AFB, AL...assistance in gaining research material on the Domestic Preparedness Program. Finally, a special thank-you to my wife, Cecilia , and our daughter Liliana

Evidence for increased olfactory receptor gene repertoire size in two nocturnal bird species with well-developed olfactory ability

PubMed Central

Steiger, Silke S; Fidler, Andrew E; Kempenaers, Bart

2009-01-01

Background In vertebrates, the molecular basis of the sense of smell is encoded by members of a large gene family, namely olfactory receptor (OR) genes. Both the total number of OR genes and the proportion of intact OR genes in a genome may indicate the importance of the sense of smell for an animal. There is behavioral, physiological, and anatomical evidence that some bird species, in particular nocturnal birds, have a well developed sense of smell. Therefore, we hypothesized that nocturnal birds with good olfactory abilities have evolved (i) more OR genes and (ii) more intact OR genes than closely related and presumably less 'olfaction-dependent' day-active avian taxa. Results We used both non-radioactive Southern hybridization and PCR with degenerate primers to investigate whether two nocturnal bird species that are known to rely on olfactory cues, the brown kiwi (Apteryx australis) and the kakapo (Strigops habroptilus), have evolved a larger OR gene repertoire than their day-active, closest living relatives (for kiwi the emu Dromaius novaehollandiae, rhea Rhea americana, and ostrich Struthio camelus and for kakapo the kaka Nestor meridionalis and kea Nestor notabilis). We show that the nocturnal birds did not have a significantly higher proportion of intact OR genes. However, the estimated total number of OR genes was larger in the two nocturnal birds than in their relatives. Conclusion Our results suggest that ecological niche adaptations such as daily activity patterns may have shaped avian OR gene repertoires. PMID:19467156

Behavior and Characteristics of Sap-Feeding North Island kākā (Nestor meridionalis septentrionalis) in Wellington, New Zealand.

PubMed

Charles, Kerry E; Linklater, Wayne L

2013-08-16

The North Island kākā (Nestor meridionalis septentrionalis), a threatened New Zealand native parrot, was successfully reintroduced to an urban sanctuary in Wellington, New Zealand. Conflict has recently begun to emerge with Wellington City residents due to tree damage caused by kākā sap foraging. Little is known about sap foraging behavior of kākā, and this study aimed to gain a greater understanding of this behavior, and to test hypotheses that sap feeding is predominantly a female activity and that one technique, forming transverse gouges through bark, may be restricted to adult kākā. We used instantaneous scan sampling to record the behavior of kākā during 25 60-100 minute observation periods at Anderson Park, Wellington Botanic Garden, and during 13 opportunistic observations of sap feeding kākā in Wellington City. Forty-one observations of sap feeding were made of 21 individually-identified birds. Sap feeding birds were predominantly young and, based on estimated sex, females were no more likely to sap feed than males (exact binomial test p = 0.868). Twenty of the 21 identified sap feeding kākā utilized supplementary feeding stations at Zealandia-Karori Wildlife Sanctuary. Kākā were observed defending sap feeding sites from tui (Prosthemadera novaeseelandiae) and conspecifics. Sap appears to be an important resource for kākā across sexes and life stages, and provision of supplementary food is unlikely to reduce sap feeding and tree damage in Wellington City.

Ancient and Contemporary DNA Reveal a Pre-Human Decline but No Population Bottleneck Associated with Recent Human Persecution in the Kea (Nestor notabilis)

PubMed Central

Dussex, Nicolas; Rawlence, Nicolas J.; Robertson, Bruce C.

2015-01-01

The impact of population bottlenecks is an important factor to consider when assessing species survival. Population declines can considerably limit the evolutionary potential of species and make them more susceptible to stochastic events. New Zealand has a well documented history of decline of endemic avifauna related to human colonization. Here, we investigate the genetic effects of a recent population decline in the endangered kea (Nestor notabilis). Kea have undergone a long-lasting persecution between the late 1800s to 1970s where an estimated 150,000 kea were culled under a governmental bounty scheme. Kea now number 1,000–5,000 individuals in the wild and it is likely that the recent population decline may have reduced the genetic diversity of the species. Comparison of contemporary (n = 410), historical (n = 15) and fossil samples (n = 4) showed a loss of mitochondrial diversity since the end of the last glaciation (Otiran Glacial) but no loss of overall genetic diversity associated with the cull. Microsatellite data indicated a recent bottleneck for only one population and a range-wide decline in Ne dating back some 300 – 6,000 years ago, a period predating European arrival in NZ. These results suggest that despite a recent human persecution, kea might have experienced a large population decline before stabilizing in numbers prior to human settlement of New Zealand in response to Holocene changes in habitat distribution. Our study therefore highlights the need to understand the respective effects of climate change and human activities on endangered species dynamics when proposing conservation guidelines. PMID:25719752

Generation of 3D templates of active sites of proteins with rigid prosthetic groups.

PubMed

Nebel, Jean-Christophe

2006-05-15

With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein structures is an exciting prospect: active sites could be better understood, protein functions and protein 3D structures could be predicted more accurately. Although patterns can already be generated at the fold and topological levels, no system produces high-resolution 3D patterns including atom and cavity positions. To address this challenge, our research focuses on generating patterns from proteins with rigid prosthetic groups. Since these groups are key elements of protein active sites, the generated 3D patterns are expected to be biologically meaningful. In this paper, we present a new approach which allows the generation of 3D patterns from proteins with rigid prosthetic groups. Using 237 protein chains representing proteins containing porphyrin rings, our method was validated by comparing 3D templates generated from homologues with the 3D structure of the proteins they model. Atom positions were predicted reliably: 93% of them had an accuracy of 1.00 A or less. Moreover, similar results were obtained regarding chemical group and cavity positions. Results also suggested our system could contribute to the validation of 3D protein models. Finally, a 3D template was generated for the active site of human cytochrome P450 CYP17, the 3D structure of which is unknown. Its analysis showed that it is biologically meaningful: our method detected the main patterns of the cytochrome P450 superfamily and the motifs linked to catalytic reactions. The 3D template also suggested the position of a residue, which could be involved in a hydrogen bond with CYP17 substrates and the shape and location of a cavity. Comparisons with independently generated 3D models comforted these hypotheses. Alignment software (Nestor3D) is available at http://www.kingston.ac.uk/~ku33185/Nestor3D.html

Realization of personal telemedicine in the interface point of emergency services and preventive care

NASA Astrophysics Data System (ADS)

Golovner, Michal

2002-08-01

SHL was founded in 1987, based in Tel Aviv Israel. SHL is a leading provider of personal telemedicine systems and services. SHL operates a medical call center in Israel that offers remote monitoring services to approx.65000 subscribers. Currently SHL is implementing successful Israeli business model in international markets and has established a number of strategic relationships with leading consumer and healthcare companies in Europe, including Philips Electronics and Nestor Healthcare. As of June 2002, Raytel Medical, a US based company, became a wholly- owned subsidiary of SHL. Core products are FDA approved, carry the CE mark and have a long established reputation in the medical community and a successful track record. SHL offers subscribers and their physicians, Internet access to selected medical data. SHL is publicly traded on the SWX market, Switzerland).

Modeling MgII Absorbers from SDSS Spectroscopic and Imaging Catalogs

NASA Astrophysics Data System (ADS)

Rimoldini, L. G.; Menard, B.; Nestor, D. B.; Rao, S. M.; Sheth, R. K.; Turnshek, D. A.; Zibetti, S.; Feather, S.; Quider, A.

2005-12-01

The detection of more than 14,000 MgII absorption doublets along the sight-lines to SDSS DR4 QSOs (pursued by Turnshek, Nestor, Rao, and collaborators) has produced the largest sample of MgII absorbers to date in the redshift interval 0.37 < z < 2.30. The statistical relation between galaxies and MgII systems is investigated by cross-correlating the spectroscopic MgII catalog with the SDSS imaging catalog of galaxies in the neighborhood of QSO sight-lines. A model for MgII absorbers is derived to account for the measured MgII rest equivalent width distribution and the absorbing galaxy properties (e.g., luminosity, impact parameter, and morphological type). Some preliminary results of our analysis are presented. This work was supported in part by the National Science Foundation. L.G.R. acknowledges further support from the Z. Daniel's Predoctoral Fellowship.

Evolution of HI from Z=5 to the present

NASA Technical Reports Server (NTRS)

Storrie-Lombardi, L. J.

2002-01-01

Studies of damped Lya systems provide us with a good measure of the evolution of the HI column density distribution function and the contribution to the comoving mass density in neutral gas out to redshifts of z = 5 . The column density distribution function at high redshift steepens for the highest column density HI absorbers, though the contribution to the comoving mass density of neutral gas remains fiat from 2 < z < 5 . Results from studies at z < 2 are finding substantial numbers of damped absorbers identified from MgII absorption, compared to previous blind surveys. These results indicate that the contribution to the comoving mass density in neutral gas may be constant from z 0 to z 5. Details of recent work in the redshift range z < 2 work is covered elsewhere in this volume (see D. Nestor). We review here recent results for the redshift range 2 < z < 5.

Death by chocolate: a fatal problem for an inquisitive wild parrot.

PubMed

Gartrell, B D; Reid, C

2007-06-01

An adult male kea (Nestor notabilis) in good body condition was found dead at Aoraki/Mt Cook Village, in the Southern Alps of New Zealand. The bird had previously been involved in behavioural tests of problem-solving ability. The bird had substantial subcutaneous and abdominal reserves of fat. The crop contained 20 g of what appeared to be dark chocolate; a conservative estimate of the dose of methylxanthines ingested by the bird was 250 mg/kg theobromine, 20 mg/kg caffeine and 3 mg/kg theophylline. Histopathological examination revealed acute degenerative changes to hepatocytes, renal tubules, and cerebrocortical neurons. Acute combination methylxanthine toxicity after opportunistic ingestion of chocolate. This is the first report of the pathological findings of methylxanthine toxicity in a wild parrot, and illustrates the need to ensure that kea are protected from the toxic by-products of human habitation, and the difficulties in ensuring this against a neophilic, inquisitive and innovative parrot.

Argentina: no lesson learned.

PubMed

Iriart, Celia; Waitzkin, Howard

2006-01-01

This article examines the political, ideological, social, and economic processes by which the Argentinean economy was transformed, the structural consequences, and the policies responsible for dismantling the welfare state. The health care system reform during the 1990s was an important component in accomplishing the last objective. Analyses of the policies adopted after the crisis of 2001 reveal that, despite the discourse against international financial institutions, President Nestor Kirchner, elected in 2002, followed the same approach by accepting and applying the second generation of health reforms recommended by the World Bank and the Inter-American Development Bank with additional pressure from the World Trade Organization and several free trade agreements. This "new reform" furthered business opportunities for multinational corporations while further shrinking the state administration's role in supplying health, education, and other social services to people who need them more than ever. Social movements have emerged that are developing alternative projects and showing that, when the base is solidarity, "another world is possible."

Behavior and Characteristics of Sap-Feeding North Island kākā (Nestor meridionalis septentrionalis) in Wellington, New Zealand

PubMed Central

Charles, Kerry E.; Linklater, Wayne L.

2013-01-01

Simple Summary Understanding the behavior of problem animal species assists in understanding and mitigating problems caused by wildlife in urban landscapes. The kākā, a threatened New Zealand native parrot, causes damage to trees while feeding on sap. Through observations of sap foraging kākā in Wellington City, this study builds on the limited knowledge of sap feeding and tests hypotheses about the age and sex of sap feeding birds. We found that sap feeding likely occurs in both sexes and across age groups, and that sap feeding birds also utilize supplementary food. This study suggests that sap is an important food source for kākā and that further provision of supplementary food is unlikely to reduce sap feeding and associated tree damage. Abstract The North Island kākā (Nestor meridionalis septentrionalis), a threatened New Zealand native parrot, was successfully reintroduced to an urban sanctuary in Wellington, New Zealand. Conflict has recently begun to emerge with Wellington City residents due to tree damage caused by kākā sap foraging. Little is known about sap foraging behavior of kākā, and this study aimed to gain a greater understanding of this behavior, and to test hypotheses that sap feeding is predominantly a female activity and that one technique, forming transverse gouges through bark, may be restricted to adult kākā. We used instantaneous scan sampling to record the behavior of kākā during 25 60–100 minute observation periods at Anderson Park, Wellington Botanic Garden, and during 13 opportunistic observations of sap feeding kākā in Wellington City. Forty-one observations of sap feeding were made of 21 individually-identified birds. Sap feeding birds were predominantly young and, based on estimated sex, females were no more likely to sap feed than males (exact binomial test p = 0.868). Twenty of the 21 identified sap feeding kākā utilized supplementary feeding stations at Zealandia-Karori Wildlife Sanctuary. Kākā were observed defending sap feeding sites from tui (Prosthemadera novaeseelandiae) and conspecifics. Sap appears to be an important resource for kākā across sexes and life stages, and provision of supplementary food is unlikely to reduce sap feeding and tree damage in Wellington City. PMID:26479536

Professor Monastyrski N.D. (1847–1888): One of the Forgotten Pioneers of Biliary Surgery

PubMed Central

Gachabayov, Mahir; Kubachev, Kubach

2017-01-01

Today, the ingenious and untimely deceased surgeon Monastyrski’s name is almost lost in the history of medicine and means little, if anything, to young surgeons. Monastyrski Nestor Dmitrievich was born in 1847 in Czerniowce and graduated from the medical faculty of the University of Vienna. Deeply inspired by the stars of European medicine and surgery: Billroth, Kaposi, Mikulicz, he became a brilliant surgeon and teacher. Monastyrski performed the first gastroenterostomy in Russia and was one of the pioneers of the aseptic method in Russia. In May 1887 he performed the historical first cholecystojejunostomy in the world. In 1888, exhausted by a tumor of the right kidney, Monastyrski insisted on surgery which resulted in his death several hours later. The department of surgery which was founded by Monastyrski N.D. in the Clinical Institute of Grand Duchess Elena Pavlovna (today – North-Western State Medical Academy named after I.I. Mechnikov) was named after him. PMID:28373287

[Living arrangements and social networks of elders. A selection of findings from a NESTOR-Study].

PubMed

Knipscheer, C P; Dykstra, P A; van Tilburg, T G; de Jong-Gierveld, J

1998-06-01

This article presents an overview of the design and results of the NESTOR survey 'Living Arrangements and Social Networks of Older Adults', an empirical study, started in 1992, among a representative sample of 4495 people, aged 55-89, selected from the population registers of 11 municipalities in the Netherlands. Questions were asked about living arrangements, the composition and functions of social networks, and important transitions in the marital, parental and occupational careers. The results indicated a wide diversity in living arrangements and social networks, a diversity which is particularly visible among the young old. They not only have larger networks, but are also more likely to live alone, to be divorced and to participate in shared housing arrangements. The networks vary considerably in size, from 0 to more than 40 important relationships. The decrease in network size with age appears to be directly related to specific life events such as widowhood, physical handicaps, residential moves etc. About 2/3 of the relationships are family relationships: parents, children (in law), grandchildren (in law), brothers and sisters (in law), uncles and aunts. Older people tend to be in touch at least once a month with the majority of close family members. The intensity of supportive exchanges (giving and receiving instrumental and emotional support in the twelve relationships with the highest levels of contact) is moderate, however mostly in balance. Only the very old receive somewhat more instrumental support and give considerably less than the 'young-old'. We studied the shift in balance between giving and receiving over a period of 12 months among a small proportion of the sample, checking a central hypothesis of exchange theory. In some cases a new balance evolves. In others the relationship continues to exist for a number of reasons, despite the imbalance. Early life experiences appear to be important for later life outcomes. Those who experienced the divorce of their parents before the age of 15 or those whose parents lived apart permanently (e.g. unmarried mothers) have a smaller social network and feel more lonely. Marital history has an impact on patterns of informal and formal care. E.g., those respondents without a partner who have children are less likely to use formal care than those who are childless. Among divorced elderly the use of formal care not only varies between men and women but also differs according to the marriage in which the children are born, first or second marriage. Occupational history is strongly related to the income level of older women living alone.

U-series ages of solitary corals from the California coast by mass spectrometry

USGS Publications Warehouse

Stein, Martin; Wasserburg, G.J.; Lajoie, K.R.; Chen, J.-H.

1991-01-01

The purpose of this study is to evaluate the feasibility of dating fossil solitary corals from Pleistocene marine strandlines outside tropical latitudes using the recently developed high sensitivity, high-precision U-series technique based on thermal-ionization mass-spectrometry (TIMS). The TIMS technique is much more efficient than conventional a spectrometry and, as a result, multiple samples of an individual coral skeleton, or different specimens from the same bed can be analyzed. Detached and well-rounded fossil specimens of the solitary coral Balanophyllia elegans were collected from relict littoral deposits on emergent marine terraces along the California coast at Cayucos terrace (elevation 8 m, previously dated at 124 and 117 Ky by ?? counting), Shell Beach terrace (elevation about 25 m, previously undated), Nestor terrace, San Diego (elevation 23 m, previously dated at 131 to 109 Ky ), Bird Rock terrace, San Diego ( elevation 8 m, previously dated at 81 Ky ). Attached living specimens were collected from the intertidal zone on the modern terrace at Moss Beach. Concentrations of 232Th in both living and fossil specimens are much higher than in reef-building corals (12 to 624 pmol/g vs. 0.1 to 1.6 pmol/g, respectively). However, because 230Th/232Th in Balanophyllia elegans are very low (2.22 ?? 10-3 to 4.33 ?? 10-4), the high 232Th concentrations have negligible effect on the 230Th-234U dates. The high 232Th concentration in the living specimen (33.1 pmol/g) indicates that a significant amount of 232Th is incorporated in the aragonitic skeleton during growth, or attached to clay-sized silicates trapped in the skeletal material. The calculated initial 234U activities in the fossil specimens of Balanophyllia elegans are higher than the 234U activity in modern seawater or in the modern specimen. The higher initial activities could possibly reflect the influx of 234U-enriched continental water into Pleistocene coastal waters, or it could reflect minor diagenetic alteration, a persistent and fundamental problem in dating all corals. Samples from a compound specimen from the Cayucos terrace were subjected to different preparation procedures. Samples prepared by a standard acid washing procedure yielded 230Th-234U ages of 125, 123, and 122 Ky, whereas samples prepared by an abbreviated procedure without acid washing yield significantly lower ages of 113 and 112 Ky. Two other specimens from the same bed yielded 230Th-234U ages of 118 and 115 Ky. Also, two specimens from a stratigraphically higher bed yielded ages of 120 and 117 Ky, and three specimens from a lower bed yield ages of 115, 113, and 101 Ky. Nine of the twelve ages of the treated samples from the Cayucos terrace range from 125 to 113 Ky. However, the ages do not follow the stratigraphie order. Two possible interpretations are ( 1 ) the age of the terrace deposit is 125 Ky and all younger ages reflect variable diagenetic alteration or (2) the age of the terrace is 125 to 113 Ky and the ages reflect sediment reworking over a period of 12 Ky. Three specimens from a single bed on the Shell Beach terrace yield ages of 126, 122, and 121 Ky, similar to the older ages from Cayucos. The ages of solitary corals from the Cayucos and Shell Beach terraces are similar to ages of reef-building corals from terraces at numerous tropical localities. These are correlated with the last interglacial sea-level highstand, which probably stood 2 to 10 m above present sea level. The youngest ages and present elevations of the Cayucos and Shell Beach terraces yield tectonic uplift rates of 0.01 and 0.15 m/Ky, respectively, assuming the original elevation of each terrace was 7 m. Four specimens from the basal gravel on the Nestor terrace yielded ages of 145, 143, 137, and 133 Ky. The three oldest ages, however, are older than that associated with the last interglacial. The possible explanations for these older ages are ( 1 ) diagenic alteration or ( 2 ) the Nestor terrace deposits reflect in s

Criteria for the evaluation and certification of long-term digital archives in the earth sciences

NASA Astrophysics Data System (ADS)

Klump, Jens

2010-05-01

Digital information has become an indispensable part of our cultural and scientific heritage. Scientific findings, historical documents and cultural achievements are to a rapidly increasing extent being presented in electronic form - in many cases exclusively so. However, besides the invaluable advantages offered by this form, it also carries a serious disadvantage: users need to invest a great deal of technical effort in accessing the information. Also, the underlying technology is still undergoing further development at an exceptionally fast pace. The rapid obsolescence of the technology required to read the information combined with the frequently imperceptible physical decay of the media themselves represents a serious threat to preservation of the information content. Many data sets in earth science research are from observations that cannot be repeated. This makes these digital assets particularly valuable. Therefore, these data should be kept and made available for re-use long after the end of the project from which they originated. Since research projects only run for a relatively short period of time, it is advisable to shift the burden of responsibility for long-term data curation from the individual researcher to a trusted data repository or archive. But what makes a trusted data repository? Each trusted digital repository has its own targets and specifications. The trustworthiness of digital repositories can be tested and assessed on the basis of a criteria catalogue. This is the main focus of the work of the nestor working group "Trusted repositories - Certification". It identifies criteria which permit the trustworthiness of a digital repository to be evaluated, both at the organisational and technical levels. The criteria are defined in close collaboration with a wide range of different memory organisations, producers of information, experts and other interested parties. This open approach ensures a high degree of universal validity, suitability for daily practical use and also broad-based acceptance of the results. The criteria catalogue is also intended to present the option of documenting trustworthiness by means of certification in a standardised national or international process. The criteria catalogue is based on the Reference Model for an Open Archival Information System (OAIS, ISO 14721:2003) With its broad approach, the nestor criteria catalogue for trusted digital repositories has to remain on a high level of abstraction. For application in the earth sciences the evaluation criteria need to be transferred into the context of earth science data and their designated user community. This presentation offers a brief introduction to the problems surrounding the long-term preservation of digital objects. This introduction is followed by a proposed application of the criteria catalogue for trusted digital repositories to the context of earth science data and their long-term preservation.

The relation between social embeddedness and loneliness among older lesbian, gay, and bisexual adults in the Netherlands.

PubMed

Fokkema, Tineke; Kuyper, Lisette

2009-04-01

Research has shown that aging lesbians, gay men, and bisexuals (LGBs) often experience feelings of loneliness. The main aim of this study was to examine whether older LGB adults in the Netherlands are lonelier than their heterosexual counterparts and, if so, whether the higher levels of loneliness can be attributed to a lower degree of social embeddedness. Using data from the Gay Autumn project and the NESTOR survey on Living Arrangements and Social Networks of Older Adults, we found that LGB elders were significantly lonelier and less socially embedded than heterosexual elders. Compared with their heterosexual peers, older LGBs were more likely to have experienced divorce, to be childless or to have less intensive contact with their children. They also had less intensive contact with other members of their families and they were less frequent churchgoers. Their weaker level of social embeddedness, however, only partially explained the stronger feelings of loneliness among older LGB adults. Nor could their higher levels of loneliness be attributed to other, non-social embeddedness factors (health, living conditions, self-esteem, and socioeconomic status). Emphasis on other aspects of social embeddedness, such as the quality of social relationships in the private domain and minority stress, is an important challenge for future research.

Gas chromatographic-mass spectrometric characterisation of plant gums in samples from painted works of art.

PubMed

Bonaduce, Ilaria; Brecoulaki, Hariclia; Colombini, Maria Perla; Lluveras, Anna; Restivo, Vincenzo; Ribechini, Erika

2007-12-21

This paper presents an analytical GC-MS procedure to study the chemical composition of plant gums, determining aldoses and uronic acids in one step. The procedure is based on the silylation of aldoses and uronic acids, released from plant gums by microwave assisted hydrolysis, and previously converted into the corresponding diethyl-dithioacetals and diethyl-dithioacetal lactones. Using this method only one peak for each compound is obtained, thus providing simple and highly reproducible chromatograms. The analytical procedure was optimised using reference samples of raw plant gums (arabic, karaya, ghatti, guar, locust bean and tragacanth, cherry, plum and peach gums), commercial watercolours and paint layers prepared according to ancient recipes at the Opificio delle Pietre Dure of Florence (Italy). To identify gum media in samples of unknown composition, a decisional schema for the gum identification and the principal component analysis of the relative sugar percentage contents were employed. The procedure was used to study samples collected from wall paintings from Macedonian tombs (4th-3rd centuries bc) and from the Mycenaean "Palace of Nestor" (13th century bc) in Pylos, Greece. The presence of carbohydrates was ascertained and plant gum binders (fruit and a mixture of tragacanth and fruit tree gums) were identified in some of the samples.

Internal conversion coefficients of high multipole transitions: Experiment and theories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerl, J.; Vijay Sai, K.; Sainath, M.

A compilation of the available experimental internal conversion coefficients (ICCs), {alpha}{sub T}, {alpha}{sub K}, {alpha}{sub L}, and ratios K/L and K/LM of high multipole (L > 2) transitions for a number of elements in the range 21 {<=} Z {<=} 94 is presented. Our listing of experimental data includes 194 data sets on 110 E3 transitions, 10 data sets on 6 E4 transitions, 11 data sets on 7 E5 transitions, 38 data sets on 21 M3 transitions, and 132 data sets on 68 M4 transitions. Data with less than 10% experimental uncertainty have been selected for comparison with the theoreticalmore » values of Hager and Seltzer [R.S. Hager, E.C. Seltzer, Nucl. Data Tables A 4 (1968) 1], Rosel et al. [F. Roesel, H.M. Fries, K. Alder, H.C. Pauli, At. Data Nucl. Data Tables 21 (1978) 91], and BRICC. The relative percentage deviations (%{delta}) have been calculated for each of the above theories and the averages (%{delta}-bar) are estimated. The Band et al. [I.M. Band, M.B. Trzhaskovskaya, C.W. Nestor Jr., P.O. Tikkanen, S. Raman, At. Data Nucl. Data Tables 81 (2002) 1] tables, using the BRICC interpolation code, are seen to give theoretical ICCs closest to experimental values.« less

Emblematic forest dwellers reintroduced into cities: resource selection by translocated juvenile kaka.

PubMed

Recio, Mariano R; Payne, Keith; Seddon, Philip J

2016-02-01

Urbanization and exotic species are major threats to the conservation of forest-dependent wildlife species. Some emblematic species, indicators of habitat quality for the conservation of other species, might successfully be reintroduced within cities when habitat restoration and pest management programs are combined. We studied the landscape resource selection of juvenile kaka Nestor meridionalis tracked with Global Positioning System (GPS) units and released into the predator-free reserve of Zealandia in Wellington city, New Zealand. Kaka moved beyond the predator exclusion fence into urban suburbs. The home range size and areas of high use estimated using local convex hull ( a -LoCoH) ranged from 20 to 240 ha and 2 to 21 ha, respectively. Using resource selection functions and model selection we found that native forest patches and urban areas close to the reserve were selected by kaka to establish their home ranges. At a lower scale of selection (i.e., selection of habitats within home ranges), kaka selected the same habitat, but not necessarily those close to the reserve. Native forest patches throughout the city can facilitate the dispersal of individuals, while the reserve provides protection and opportunities for supplementary feeding. Urban areas might have been selected due to the placement of feeders in private backyards. Survival of forest-dwelling species in cities requires careful urban planning and management to provide the necessary habitat patches, refugia, and food sources.

[The polymorphism and distribution of B chromosomes in germline and somatic cells of Tscherskia triton de Winton (Rodentia, Cricetinae)].

PubMed

Borisov, Iu M

2012-05-01

The karyotypes of 13 greater long-tailed hamsters (Tscherskia triton de Winton, 1899) (eight males and five females) from Primorskii krai (Russia), including six males and one female from the vicinity of the city of Ussuriisk and two males and four females from the vicinity of the village of Pogranichnyi, have been studied. The karyotypes of five males (four from the vicinity of Ussuriisk and one from the vicinity of Pogranichnyi) have been found to contain one or two small acrocentric B chromosomes each. In males with B chromosomes, each germline cell contains one or two B chromosomes. The proportion of somatic cells carrying B chromosomes varies from 34.9 to 55.9% in these males. Karyological study of a total of 45 Tscherskia triton (30 males and 15 females) from Primorskii krai has been performed, B chromosomes being found in only five males (11.1%). In T. triton populations of Korea and China, also only a few animals have been found to carry one or two B chromosomes. The greater long-tailed hamster belongs to the monotypic genus Tscherskia; the animals described earlier under the names T. (Cricettilus) triton albipes Ognev, 1914 and T. (Cricettilus) triton nestor Thomas, 1907 belong to the only species in the genus, T. triton de Winton, 1899.

The last interglacial period on the Pacific Coast of North America: Timing and paleoclimate

USGS Publications Warehouse

Muhs, D.R.; Simmons, K.R.; Kennedy, G.L.; Rockwell, T.K.

2002-01-01

New, high-precision U-series ages of solitary corals (Balanophyllia elegans) coupled with molluscan faunal data from marine terraces on the Pacific Coast of North America yield information about the timing and warmth of the last interglacial sea-level highstand. Balanophyllia elegans takes up U in isotopic equilibrium with seawater during growth and shortly after death. Corals from the second terrace on San Clemente Island (offshore southern California), the third terrace on Punta Banda (on the Pacific Coast of northern Baja California), and the Discovery Point Formation on Isla de Guadalupe (in the Pacific Ocean offshore Baja California) date to the peak of the last interglacial period and have U-series ages ranging from ca. 123 to 114 ka. The first terrace on Punta Banda has corals with ages ranging from ca. 83 to 80 ka, which corresponds to a sea-level highstand formed in the late last interglacial period. U-series analyses of corals from the Cayucos terrace (central California) and the Nestor terrace at Point Loma (southern California) show that these fossils have evidence of open-system history, similar to what has been reported by other workers for the same localities. Nevertheless, a model of continuous, secondary U and Th uptake shows that two ages of corals are likely present at these localities, representing the ca. 105 and ca. 120 ka sea-level highstands reported elsewhere. U-series ages of last interglacial corals from the Pacific Coast overlap with, but are on average younger than the ages of corals from Barbados, the Bahamas, and Hawaii. This age difference is explained by the nature of the geomorphic response to sea-level change: fringing or barrier reefs on low-latitude coastlines have an accretionary growth style that keeps pace with rising sea level, whether on a tectonically rising or stable coastline. In contrast, midlatitude, high-energy coastlines are sites of platform cutting during the early part of a sea-level high stand and terrace scouring and concomitant sediment and fossil deposition as sea level starts to recede. The youngest ages of corals from the Pacific Coast suggest that sea level was still relatively high at ca. 116 ka, which is not in agreement with other estimates of relatively large global ice volume at that time. Reliably dated, ca. 120 ka marine-terrace deposits on the Pacific Coast have fossil mollusks that indicate water temperatures as warm or warmer than at present. In contrast, ca. 80 ka marine deposits reported here and elsewhere have fossil mollusks indicating cooler-than-modern water temperatures. The presence of both ca. 105 ka and ca. 120 ka corals on the Nestor and Cayucos terraces explains a previously enigmatic mixture of warm-water and cool-water mollusks. At ca. 105 ka, a relatively high sea level with cool waters may have "captured" the terrace formed during the 120 ka sea-level highstand, in areas of low uplift rate. The inference of cooler-than-modern waters off the Pacific Coast of North America at ca. 80 ka and ca. 105 ka, based on marine-terrace faunas, does not agree with estimates of sea-surface temperatures derived from alkenone studies in the Santa Barbara Basin. However, cooler water temperatures at these times are in agreement with paleo-temperature estimates from planktonic foraminiferal data for the Santa Barbara Basin. All records, from central California to Baja California, whether from marine terraces or offshore cores, indicate at least seasonably warmer-than-modern waters during the peak of the last interglacial period at ca. 120 ka.

More than one way to see it: Individual heuristics in avian visual computation

PubMed Central

Ravignani, Andrea; Westphal-Fitch, Gesche; Aust, Ulrike; Schlumpp, Martin M.; Fitch, W. Tecumseh

2015-01-01

Comparative pattern learning experiments investigate how different species find regularities in sensory input, providing insights into cognitive processing in humans and other animals. Past research has focused either on one species’ ability to process pattern classes or different species’ performance in recognizing the same pattern, with little attention to individual and species-specific heuristics and decision strategies. We trained and tested two bird species, pigeons (Columba livia) and kea (Nestor notabilis, a parrot species), on visual patterns using touch-screen technology. Patterns were composed of several abstract elements and had varying degrees of structural complexity. We developed a model selection paradigm, based on regular expressions, that allowed us to reconstruct the specific decision strategies and cognitive heuristics adopted by a given individual in our task. Individual birds showed considerable differences in the number, type and heterogeneity of heuristic strategies adopted. Birds’ choices also exhibited consistent species-level differences. Kea adopted effective heuristic strategies, based on matching learned bigrams to stimulus edges. Individual pigeons, in contrast, adopted an idiosyncratic mix of strategies that included local transition probabilities and global string similarity. Although performance was above chance and quite high for kea, no individual of either species provided clear evidence of learning exactly the rule used to generate the training stimuli. Our results show that similar behavioral outcomes can be achieved using dramatically different strategies and highlight the dangers of combining multiple individuals in a group analysis. These findings, and our general approach, have implications for the design of future pattern learning experiments, and the interpretation of comparative cognition research more generally. PMID:26113444

Learning in Alzheimer’s Disease Is Facilitated by Social Interaction

PubMed Central

Duff, Melissa C.; Gallegos, Diana R.; Cohen, Neal J.; Tranel, Daniel

2014-01-01

Seminal work in Gary Van Hoesen’s laboratory at Iowa in the early 1980s established that the hallmark neuropathology of Alzheimer’s disease (AD; neurofibrillary tangles) had its first foothold in specific parts of the hippocampal formation and entorhinal cortex, effectively isolating the hippocampus from much of its input and output and causing the distinctive impairment of new learning that is the leading early characteristic of the disease (Hyman et al., 1984). The boundaries and conditions of the anterograde memory defect in patients with AD have been a topic of intense research interest ever since (e.g., Graham and Hodges, 1977; Nestor et al., 2006). For example, it has been shown that patients with AD may acquire some new semantic information through methods such as errorless learning, but learning under these conditions is typically slow and inefficient. Drawing on a learning paradigm (a collaborative referencing task) that was previously shown to induce robust and enduring learning in patients with hippocampal amnesia, we investigated whether this task would be effective in promoting new learning in patients with AD. We studied five women with early-stage AD and 10 demographically matched healthy comparison participants, each interacting with a familiar communication partner. AD pairs displayed significant and enduring learning across trials, with increased accuracy and decreased time to complete trials, in a manner indistinguishable from healthy comparison pairs, resulting in efficient and economical communication. The observed learning here most likely draws on neural resources outside the medial temporal lobes. These interactive communication sessions provide a potent learning environment with significant implications for memory intervention. PMID:23881834

Learning in Alzheimer's disease is facilitated by social interaction.

PubMed

Duff, Melissa C; Gallegos, Diana R; Cohen, Neal J; Tranel, Daniel

2013-12-15

Seminal work in Gary Van Hoesen's laboratory at Iowa in the early 1980s established that the hallmark neuropathology of Alzheimer's disease (AD; neurofibrillary tangles) had its first foothold in specific parts of the hippocampal formation and entorhinal cortex, effectively isolating the hippocampus from much of its input and output and causing the distinctive impairment of new learning that is the leading early characteristic of the disease (Hyman et al., 1984). The boundaries and conditions of the anterograde memory defect in patients with AD have been a topic of intense research interest ever since (e.g., Graham and Hodges, 1977; Nestor et al., 2006). For example, it has been shown that patients with AD may acquire some new semantic information through methods such as errorless learning, but learning under these conditions is typically slow and inefficient. Drawing on a learning paradigm (a collaborative referencing task) that was previously shown to induce robust and enduring learning in patients with hippocampal amnesia, we investigated whether this task would be effective in promoting new learning in patients with AD. We studied five women with early-stage AD and 10 demographically matched healthy comparison participants, each interacting with a familiar communication partner. AD pairs displayed significant and enduring learning across trials, with increased accuracy and decreased time to complete trials, in a manner indistinguishable from healthy comparison pairs, resulting in efficient and economical communication. The observed learning here most likely draws on neural resources outside the medial temporal lobes. These interactive communication sessions provide a potent learning environment with significant implications for memory intervention. Copyright © 2013 Wiley Periodicals, Inc.

A preliminary survey of Chlamydia psittaci genotypes from native and introduced birds in New Zealand.

PubMed

Gedye, K R; Fremaux, M; Garcia-Ramirez, J C; Gartrell, B D

2018-05-01

To describe the Chlamydia psittaci genotypes in samples from native and introduced birds from New Zealand by analysis of the sequence variation of the ompA gene. DNA was extracted from samples collected from a non-random sample of birds; either swabs from live asymptomatic birds or birds with clinical signs, or formalin-fixed, paraffin-embedded (FFPE) samples from historical post-mortem cases. The presence of C. psittaci in all samples had been confirmed using a quantitative PCR assay. The C. psittaci ompA gene was amplified and sequenced from samples from 26 native and introduced infected birds comprising 12 different species. These sequences were compared to published available C. psittaci genotypes. Genotypes A and C of C. psittaci were identified in the samples. Genotype A was identified in samples from nine birds, including various native and introduced species. Genotype C was identified in samples from 16 different waterfowl species, and a mixed infection of both genotypes was found in a kaka (Nestor meridionalis). In native birds, C. psittaci infection was confirmed in seven new host species. Two genotypes (A and C) of C. psittaci were found in samples from a wider range of both native and introduced species of birds in New Zealand than previously reported. Both genotypes have been globally associated with significant disease in birds and humans. These initial results suggest the host range of C. psittaci in New Zealand birds is under-reported. However, the prevalence of C. psittaci infection in New Zealand, and the associated impact on avian and public health, remains to be determined. There are biosecurity implications associated with the importation of birds to New Zealand if there is a limited diversity of C. psittaci genotypes present.

More than one way to see it: Individual heuristics in avian visual computation.

PubMed

Ravignani, Andrea; Westphal-Fitch, Gesche; Aust, Ulrike; Schlumpp, Martin M; Fitch, W Tecumseh

2015-10-01

Comparative pattern learning experiments investigate how different species find regularities in sensory input, providing insights into cognitive processing in humans and other animals. Past research has focused either on one species' ability to process pattern classes or different species' performance in recognizing the same pattern, with little attention to individual and species-specific heuristics and decision strategies. We trained and tested two bird species, pigeons (Columba livia) and kea (Nestor notabilis, a parrot species), on visual patterns using touch-screen technology. Patterns were composed of several abstract elements and had varying degrees of structural complexity. We developed a model selection paradigm, based on regular expressions, that allowed us to reconstruct the specific decision strategies and cognitive heuristics adopted by a given individual in our task. Individual birds showed considerable differences in the number, type and heterogeneity of heuristic strategies adopted. Birds' choices also exhibited consistent species-level differences. Kea adopted effective heuristic strategies, based on matching learned bigrams to stimulus edges. Individual pigeons, in contrast, adopted an idiosyncratic mix of strategies that included local transition probabilities and global string similarity. Although performance was above chance and quite high for kea, no individual of either species provided clear evidence of learning exactly the rule used to generate the training stimuli. Our results show that similar behavioral outcomes can be achieved using dramatically different strategies and highlight the dangers of combining multiple individuals in a group analysis. These findings, and our general approach, have implications for the design of future pattern learning experiments, and the interpretation of comparative cognition research more generally. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

TwiMed: Twitter and PubMed Comparable Corpus of Drugs, Diseases, Symptoms, and Their Relations.

PubMed

Alvaro, Nestor; Miyao, Yusuke; Collier, Nigel

2017-05-03

Work on pharmacovigilance systems using texts from PubMed and Twitter typically target at different elements and use different annotation guidelines resulting in a scenario where there is no comparable set of documents from both Twitter and PubMed annotated in the same manner. This study aimed to provide a comparable corpus of texts from PubMed and Twitter that can be used to study drug reports from these two sources of information, allowing researchers in the area of pharmacovigilance using natural language processing (NLP) to perform experiments to better understand the similarities and differences between drug reports in Twitter and PubMed. We produced a corpus comprising 1000 tweets and 1000 PubMed sentences selected using the same strategy and annotated at entity level by the same experts (pharmacists) using the same set of guidelines. The resulting corpus, annotated by two pharmacists, comprises semantically correct annotations for a set of drugs, diseases, and symptoms. This corpus contains the annotations for 3144 entities, 2749 relations, and 5003 attributes. We present a corpus that is unique in its characteristics as this is the first corpus for pharmacovigilance curated from Twitter messages and PubMed sentences using the same data selection and annotation strategies. We believe this corpus will be of particular interest for researchers willing to compare results from pharmacovigilance systems (eg, classifiers and named entity recognition systems) when using data from Twitter and from PubMed. We hope that given the comprehensive set of drug names and the annotated entities and relations, this corpus becomes a standard resource to compare results from different pharmacovigilance studies in the area of NLP. ©Nestor Alvaro, Yusuke Miyao, Nigel Collier. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 03.05.2017.

The leadership team: complementary strengths or conflicting agendas?

PubMed

Miles, Stephen A; Watkins, Michael D

2007-04-01

Senior leadership teams whose members play complementary roles have been chronicled as far back as Homer's account of the Trojan War: Although King Agamemnon commanded the Greek army, Achilles, Odysseus, and Nestor each played a distinct role in defeating Troy. Today, complementary-leadership structures are common and, in some cases, even institutionalized. Think of a CEO concerned mainly with external issues and a COO who focuses internally. The authors describe four kinds of complementarity: task, expertise, cognitive, and role. The two top executives at the software company Adobe Systems, for example, represent the second kind. As CEO, Bruce Chizen draws on his sales and marketing knowledge, while COO Shantanu Narayen adds his engineering and product development expertise. Roberto Goizueta, formerly the CEO of Coca-Cola, and Douglas Ivester, his COO (who later became CEO), were famous examples of the fourth type: Goizueta, the diplomat, maintained good relations with external stakeholders; Ivester, the warrior, drove the company to defeat the competition. Bringing together two or more people with complementary strengths can compensate for the natural limitations of each. But with the benefits comes the risk of confusion, disagreement about priorities, and turf battles. Leadership succession also presents substantial challenges, especially when a COO or president who has worked in a complementary fashion with the CEO moves into the top role. An organization's board of directors and CEO can manage the risks by fostering a shared vision, common incentives, communication, and trust. They can also ensure smooth succession processes in various ways, such as brokering a gradual transfer of responsibilities or allowing the CEO and the COO to share duties as long as they maintain the logic of complementarity.

The advantage of objects over images in discrimination and reversal learning by kea, Nestor notabilis

PubMed Central

O'Hara, Mark; Huber, Ludwig; Gajdon, Gyula Kopanny

2015-01-01

Studies investigating the same paradigm but employing different methods are often directly compared in the literature. One such paradigm used to assess behavioural flexibility in animals is reversal learning. Commonly, these studies require individuals to learn the reward contingency of either solid objects presented on the ground or images presented on a touchscreen. Once learned, these contingencies are swapped. Researchers often refer to trials required to reach learning criteria from different studies, to compare the flexibility of different species, but rarely take methodological differences into account. A direct evaluation of the validity of such comparisons is lacking. To address this latent question, we confronted kea, an alpine parrot species of New Zealand and known for its behavioural flexibility, with a standard reversal learning paradigm on the touchscreen and a standard reversal learning paradigm with solid objects. The kea required significantly more trials to reach criterion in the acquisition and the reversal on the touchscreen. Also, the absolute increase in the number of trials required for the reversal was significantly greater on the touchscreen. This indicates that it is not valid to compare learning speed across studies that do not correspond in the addressed methodology. Taking into account the kea's ecology and explorative nature we discuss stimulus abstraction (limited depth cues and tactile stimulus feedback) and the spatial relation between reward and stimulus on the touchscreen as possible causes for decreased inhibition in this condition. Contrary to the absolute increase in number of trials required for the reversal, the increase in relation to the acquisition was greater with solid objects. This highlights the need for further research on the mechanisms involved causing methodology-dependent differences, some of which we discuss, in order to increase the validity of interpretations across studies and in respect to the subject's ecology. PMID:25745190

A Multilocus Molecular Phylogeny of the Parrots (Psittaciformes): Support for a Gondwanan Origin during the Cretaceous

PubMed Central

Schirtzinger, Erin E.; Matsumoto, Tania; Eberhard, Jessica R.; Graves, Gary R.; Sanchez, Juan J.; Capelli, Sara; Müller, Heinrich; Scharpegge, Julia; Chambers, Geoffrey K.; Fleischer, Robert C.

2008-01-01

The question of when modern birds (Neornithes) first diversified has generated much debate among avian systematists. Fossil evidence generally supports a Tertiary diversification, whereas estimates based on molecular dating favor an earlier diversification in the Cretaceous period. In this study, we used an alternate approach, the inference of historical biogeographic patterns, to test the hypothesis that the initial radiation of the Order Psittaciformes (the parrots and cockatoos) originated on the Gondwana supercontinent during the Cretaceous. We utilized broad taxonomic sampling (representatives of 69 of the 82 extant genera and 8 outgroup taxa) and multilocus molecular character sampling (3,941 bp from mitochondrial DNA (mtDNA) genes cytochrome oxidase I and NADH dehydrogenase 2 and nuclear introns of rhodopsin intron 1, tropomyosin alpha-subunit intron 5, and transforming growth factor ß-2) to generate phylogenetic hypotheses for the Psittaciformes. Analyses of the combined character partitions using maximum parsimony, maximum likelihood, and Bayesian criteria produced well-resolved and topologically similar trees in which the New Zealand taxa Strigops and Nestor (Psittacidae) were sister to all other psittaciforms and the cockatoo clade (Cacatuidae) was sister to a clade containing all remaining parrots (Psittacidae). Within this large clade of Psittacidae, some traditionally recognized tribes and subfamilies were monophyletic (e.g., Arini, Psittacini, and Loriinae), whereas several others were polyphyletic (e.g., Cyclopsittacini, Platycercini, Psittaculini, and Psittacinae). Ancestral area reconstructions using our Bayesian phylogenetic hypothesis and current distributions of genera supported the hypothesis of an Australasian origin for the Psittaciformes. Separate analyses of the timing of parrot diversification constructed with both Bayesian relaxed-clock and penalized likelihood approaches showed better agreement between geologic and diversification events in the chronograms based on a Cretaceous dating of the basal split within parrots than the chronograms based on a Tertiary dating of this split, although these data are more equivocal. Taken together, our results support a Cretaceous origin of Psittaciformes in Gondwana after the separation of Africa and the India/Madagascar block with subsequent diversification through both vicariance and dispersal. These well-resolved molecular phylogenies will be of value for comparative studies of behavior, ecology, and life history in parrots. PMID:18653733

Introduction: military neurosurgery, past and present.

PubMed

Klimo, Paul; Ragel, Brian T

2010-05-01

For a physician has the worth of many other warriors, both for the excision of arrows and for the administration of soothing drugs. Homer, Iliad XI.514-515 Ever since armed conflict has been used as a means to settle disputes among men, there have been those who have been tasked to mend the wounds that ravage a soldier's body from the weapons of war. The Iliad portrays the pivotal 10th year of the legendary Trojan War, during which a schism in the Greek leadership prolongs the extended siege of the city of Troy. In the midst of this martial epic come the lines quoted above, quietly attesting to the value of the military physician, even under the crude conditions of the Greek Dark Age. They are uttered by Idomeneus, one of the foremost Greeks, when he is enjoining one of his comrades, Nestor, to rescue the injured Greek physician Machaon and take him back from the line to treat his wounds. He is afraid that Machaon will be captured by the Trojans, a loss far greater than that of any other single warrior. Duty to country has helped shape the careers of many neurosurgeons, including iconic US figures such as Harvey Cushing and Donald Matson. This issue of Neurosurgical Focus celebrates the rich history of military neurosurgery from the wars of yesterday to the conflicts of today. We have been humbled by the tremendous response to this topic. The 25 articles within this issue will provide the reader with both a broad and an in-depth look at the many facets of military neurosurgery. We have attempted to group articles based on their predominant topic. We also encourage our audience to read other recently published articles. The first 8 articles relate to the current conflicts in Afghanistan and Iraq. The lead article, written by Randy Bell and colleagues from the National Naval Medical Center and Walter Reed Army Medical Center, discusses what is arguably one of the most important contributions by military neurosurgeons from these 2 conflicts: the rapid and aggressive use of decompressive craniectomies. This is followed by articles on decompressive craniectomy techniques by Ragel and colleagues and cranioplasty outcomes by Stephens and colleagues. After reading these articles, the reader will come away with an appreciation of the often complex nature of wartime penetrating and closed-head injuries and the remarkable recovery that many injured soldiers make with time.

WDS/DSA Certification - International collaboration for a trustworthy research data infrastructure

NASA Astrophysics Data System (ADS)

Mokrane, Mustapha; Hugo, Wim; Harrison, Sandy

2016-04-01

Today's research is international, transdisciplinary, and data-enabled, which requires scrupulous data stewardship, full and open access to data, and efficient collaboration and coordination. New expectations on researchers based on policies from governments and funders to share data fully, openly, and in a timely manner present significant challenges but are also opportunities to improve the quality and efficiency of research and its accountability to society. Researchers should be able to archive and disseminate data as required by many institutions or funders, and civil society to scrutinize datasets underlying public policies. Thus, the trustworthiness of data services must be verifiable. In addition, the need to integrate large and complex datasets across disciplines and domains with variable levels of maturity calls for greater coordination to achieve sufficient interoperability and sustainability. The World Data System (WDS) of the International Council for Science (ICSU) promotes long-term stewardship of, and universal and equitable access to, quality-assured scientific data and services across a range of disciplines in the natural and social sciences. WDS aims at coordinating and supporting trusted scientific data services for the provision, use, and preservation of relevant datasets to facilitate scientific research, in particular under the ICSU umbrella, while strengthening their links with the research community. WDS certifies its Members, holders and providers of data or data products, using internationally recognized standards. Certification of scientific data services is essential to ensure trustworthiness of the global research data infrastructure. It contributes to building a searchable, distributed, interoperable and sustainable research data infrastructure. Several certification standards have been developed over the last decade, such as the Network of Expertise in long-term Storage and Accessibility of Digital Resources in Germany (NESTOR) seal, German Institute for Standardization (DIN) standard 31644, Trustworthy Repositories Audit and Certification (TRAC) criteria and the International Organization for Standardization (ISO) standard 16363. In addition, the Data Seal of Approval (DSA) and WDS have set up core certification mechanisms for trusted digital repositories in 2009, which are increasingly recognized as de facto standards. While DSA emerged in Europe in the Humanities and Social Sciences, WDS started as an international initiative with historical roots in the Earth and Space Sciences. Their catalogues of requirements and review procedures are based on the same principles of openness, transparency. A unique feature of the DSA and WDS certification is that it strikes a balance between simplicity, robustness and the effort required to complete. A successful international cross-project collaboration was initiated between WDS and DSA under the umbrella of the Research Data Alliance (RDA), an international initiative started in 2013 to promote data interoperability which provided a useful and neutral forum. A joint working group was established in early 2014 to reconcile and simplify the array of certification options and improve and stimulate core certification for scientific data services. The outputs of this collaboration are a Catalogue of Common Requirements (https://goo.gl/LJZqDo) and a Catalogue of Common Procedures (https://goo.gl/vNR0q1) which will be implemented jointly by WDS and DSA.

ASCAT soil moisture data assimilation through the Ensemble Kalman Filter for improving streamflow simulation in Mediterranean catchments

NASA Astrophysics Data System (ADS)

Loizu, Javier; Massari, Christian; Álvarez-Mozos, Jesús; Casalí, Javier; Goñi, Mikel

2016-04-01

Assimilation of Surface Soil Moisture (SSM) observations obtained from remote sensing techniques have been shown to improve streamflow prediction at different time scales of hydrological modeling. Different sensors and methods have been tested for their application in SSM estimation, especially in the microwave region of the electromagnetic spectrum. The available observation devices include passive microwave sensors such as the Advanced Microwave Scanning Radiometer - Earth Observation System (AMSR-E) onboard the Aqua satellite and the Soil Moisture and Ocean Salinity (SMOS) mission. On the other hand, active microwave systems include Scatterometers (SCAT) onboard the European Remote Sensing satellites (ERS-1/2) and the Advanced Scatterometer (ASCAT) onboard MetOp-A satellite. Data assimilation (DA) include different techniques that have been applied in hydrology and other fields for decades. These techniques include, among others, Kalman Filtering (KF), Variational Assimilation or Particle Filtering. From the initial KF method, different techniques were developed to suit its application to different systems. The Ensemble Kalman Filter (EnKF), extensively applied in hydrological modeling improvement, shows its capability to deal with nonlinear model dynamics without linearizing model equations, as its main advantage. The objective of this study was to investigate whether data assimilation of SSM ASCAT observations, through the EnKF method, could improve streamflow simulation of mediterranean catchments with TOPLATS hydrological complex model. The DA technique was programmed in FORTRAN, and applied to hourly simulations of TOPLATS catchment model. TOPLATS (TOPMODEL-based Land-Atmosphere Transfer Scheme) was applied on its lumped version for two mediterranean catchments of similar size, located in northern Spain (Arga, 741 km2) and central Italy (Nestore, 720 km2). The model performs a separated computation of energy and water balances. In those balances, the soil is divided into two layers, the upper Surface Zone (SZ), and the deeper Transmission Zone (TZ). In this study, the SZ depth was fixed to 5 cm, for adequate assimilation of observed data. Available data was distributed as follows: first, the model was calibrated for the 2001-2007 period; then the 2007-2010 period was used for satellite data rescaling purposes. Finally, data assimilation was applied during the validation (2010-2013) period. Application of the EnKF required the following steps: 1) rescaling of satellite data, 2) transformation of rescaled data into Soil Water Index (SWI) through a moving average filter, where a T = 9 calibrated value was applied, 3) generation of a 50 member ensemble through perturbation of inputs (rainfall and temperature) and three selected parameters, 4) validation of the ensemble through the compliance of two criteria based on ensemble's spread, mean square error and skill and, 5) Kalman Gain calculation. In this work, comparison of three satellite data rescaling techniques: 1) cumulative distribution Function (CDF) matching, 2) variance matching and 3) linear least square regression was also performed. Results obtained in this study showed slight improvements of hourly Nash-Sutcliffe Efficiency (NSE) in both catchments, with the different rescaling methods evaluated. Larger improvements were found in terms of seasonal simulated volume error reduction.

Gravitational Wave Experiments - Proceedings of the First Edoardo Amaldi Conference

NASA Astrophysics Data System (ADS)

Coccia, E.; Pizzella, G.; Ronga, F.

1995-07-01

The Table of Contents for the full book PDF is as follows: * Foreword * Notes on Edoardo Amaldi's Life and Activity * PART I. INVITED LECTURES * Sources and Telescopes * Sources of Gravitational Radiation for Detectors of the 21st Century * Neutrino Telescopes * γ-Ray Bursts * Space Detectors * LISA — Laser Interferometer Space Antenna for Gravitational Wave Measurements * Search for Massive Coalescing Binaries with the Spacecraft ULYSSES * Interferometers * The LIGO Project: Progress and Prospects * The VIRGO Experiment: Status of the Art * GEO 600 — A 600-m Laser Interferometric Gravitational Wave Antenna * 300-m Laser Interferometer Gravitational Wave Detector (TAMA300) in Japan * Resonant Detectors * Search for Continuous Gravitational Wave from Pulsars with Resonant Detector * Operation of the ALLEGRO Detector at LSU * Preliminary Results of the New Run of Measurements with the Resonant Antenna EXPLORER * Operation of the Perth Cryogenic Resonant-Bar Gravitational Wave Detector * The NAUTILUS Experiment * Status of the AURIGA Gravitational Wave Antenna and Perspectives for the Gravitational Waves Search with Ultracryogenic Resonant Detectors * Ultralow Temperature Resonant-Mass Gravitational Radiation Detectors: Current Status of the Stanford Program * Electromechanical Transducers and Bandwidth of Resonant-Mass Gravitational-Wave Detectors * Fully Numerical Data Analysis for Resonant Gravitational Wave Detectors: Optimal Filter and Available Information * PART II. CONTRIBUTED PAPERS * Sources and Telescopes * The Local Supernova Production * Periodic Gravitational Signals from Galactic Pulsars * On a Possibility of Scalar Gravitational Wave Detection from the Binary Pulsars PSR 1913+16 * Kazan Gravitational Wave Detector “Dulkyn”: General Concept and Prospects of Construction * Hierarchical Approach to the Theory of Detection of Periodic Gravitational Radiation * Application of Gravitational Antennae for Fundamental Geophysical Problems * On Production of Gravitational Radiation by Particle Accelerators and by High Power Lasers * NESTOR: An Underwater Cerenkov Detector for Neutrino Astronomy * A Cosmic-Ray Veto System for the Gravitational Wave Detector NAUTLUS * Interferometers * Development of a 20m Prototype Laser Interferometric Gravitational Wave Detector at NAO * Production of Higher-Order Light Modes by High Quality Optical Components * Vibration Isolation and Suspension Systems for Laser Interferometer Gravitational Wave Detectors * Quality Factors of Stainless Steel Pendulum Wires * Reduction of Suspension Thermal Noises in Laser Free Masses Gravitational Antenna by Correlation of the Output with Additional Optical Signal * Resonant Detectors * Regeneration Effects in a Resonant Gravitational Wave Detector * A Cryogenic Sapphire Transducer with Double Frequency Pumping for Resonant Mass GW Detectors * Effect of Parametric Instability of Gravitational Wave Antenna with Microwave Cavity Transducer * Resonators of Novel Geometry for Large Mass Resonant Transducers * Measurements on the Gravitational Wave Antenna ALTAIR Equipped with a BAE Transducer * The Rome BAE Transducer: Perspectives of its Application to Ultracryogenic Gravitational Wave Antennas * Behavior of a de SQUID Tightly Coupled to a High-Q Resonant Transducer * High Q-Factor LC Resonators for Optimal Coupling * Comparison Between Different Data Analysis Procedures for Gravitational Wave Pulse Detection * Supernova 1987A Rome Maryland Gravitational Radiation Antenna Observations * Analysis of the Data Recorded by the Maryland and Rome Gravitational-Wave Detectors and the Seismic Data from Moscow and Obninsk Station during SN1987A * Multitransducer Resonant Gravitational Antennas * Local Array of High Frequency Antennas * Interaction Cross-Sections for Spherical Resonant GW Antennae * Signal-To-Noise Analysis for a Spherical Gravitational Wave Antenna Instrumented with Multiple Transducers * On the Design of Ultralow Temperature Spherical Gravitational Wave Detectors * List of Participants

The history of the Laboratory of Pathology of the Cluj-Napoca Oncological Institute.

PubMed

Simu, G; Buiga, R

2006-01-01

The Laboratory of Pathology of the actual "Professor Ion Chiricută" Oncological Institute of Cluj-Napoca, former "Iuliu Maniu" Institute for Cancer Study and Prophylaxis, had the privilege that in its framework carry on an important part of their activity professors Titu Vasiliu and Rubin Popa, who are forming, beside Victor Babeş, the golden trinity of the Romanian pathology. The Cancer Institute of Cluj, one of the first in the World, was founded in 1929, especially by the clear-sightedness and the efforts of Professor Iuliu Moldovan, the master of the modern Romanian school of hygiene. The clinic division was assisted by a Laboratory of Pathology, whose chief was appointed the young pathologist of high competence, Rubin Popa, associate Professor of this department of the Cluj School of Medicine. In 1942' he became director of the Institute, function accomplished until his premature disappearance in 1958. Titu Vasiliu worked in the Oncological Institute from 1949, a year after his forced retreat from the chair of pathology, up to 1958. Fortunately, his premature disappearance did not interrupt the activity of the laboratory, because the management of the Oncological Institute was committed to Ion Chiricută, an experimented and modern surgeon of Bucharest. From 1960, the Laboratory of Pathology has been led by Professor Augustin Mureşan, an experimented, rigorous and prudent pathologist, who has imprinted these indispensable qualities to his disciples learning under his leadership. The activity of the laboratory has been very favorably influenced by the presence of Professor Gheorghe Badenski from the Department of Microbiology. The collaboration with Professor Eugen Pora from Babeş-Bolyai Department of Animal Physiology and his disciples, Virgil Toma, Draga Nestor, Sena Roşculet, Carmen Stugren and Georgette Buga has carried on the performance of interesting works concerning the thymus involution in tumor-bearing hosts and its signification for the depressed immunity in the advanced stages of cancer. In the same direction, the behavior of mast cells has been studied in collaboration with Professor George Csaba from the Budapest Medical University, Department of Biology. The observations brought about were remarked by the Canadian scientist Hans Selye. Most of these works have been included in the book "Immunity and cancer", distinguished with "Victor Babeş" Prize of the Romanian Academy. The arrival in the Institute of Professor Ion Macavei, disciple of Iuliu Hatieganu and founder of the Clinical Hematology in Cluj, expert in blood and bone marrow cytology, has given a strong impulse to the studies of malignant hemopoietic diseases. The current use of cytologic and histopathologic examinations in this field of pathology and, especially, the introduction by him, for the first time in Romania, of the osteomedullary biopsy has permitted the elaboration of an appreciated work about the cytologic and histologic diagnosis of lymphadenopathies. In the histochemical-histoenzymatic period of the microscopic diagnosis, between the years 1960-1990, the laboratory has enjoyed by the advices and the material help of Professor Raymond Wegmann from the Paris University, Institute of Histochemistry, the founder-editor of the International Review of Histochemistry, from 1976, of Cellular and Molecular Biology, who visited our laboratory in 1992. From 1965, in an adjacent Laboratory of Cytogenetics, Corneliu D. Olinici has performed the first karyotypes in Cluj and has teached the method to several other specialists. Despite the technical difficulties, the works performed in the Laboratory of Pathology have succeeded sometimes to reach the quality required by Professor Chiricută to a valuable scientific work in cancerology. This performance has been obtained by a study concerning Crabtree effect variations in tumoral metastases or about lactic-dehydrogenase behavior in breast carcinomas.

One hundred years since the birth of academician Dimitar Arsov, founder and nestor of the modern internal medicine in the Republic of Macedonia.

PubMed

Polenaković, M

2013-01-01

Dimitar Arsov was born in Kriva Palanka on September 28, 1908 and died on July 2, 1974 in Skopje; he had finished elementary education in Kriva Palanka, high school (1922-1926) in Kumanovo, Macedonia and Col-lege of Medicine (1926-1932), Ph. D. University of Paris, Sorbone, France, 1936. He returned to Macedonia in 1937. In 1947 he was elected and Assistant Professor and in 1950 a Docent at the Faculty of Medicine in Skopje. He was appointed Director of the Clinic of Medicine and Head of the Chair of Internal Medicine, who served at those positions in the period 1952-74. In 1958 he was elected Professor of Internal Medicine. The first habilitation of the Medical Faculty in Skopje was defended by D. Arsov in 1954, titled: "The Effects of the Intravenous Epinephrine on the Hypersplenism of Malaria and Cala-Azar". On August 18, 1967, D. Arsov was elected Full Member and also the first member in the field of medicine of the Macedonian Academy of Sciences and Arts. The excellent experience in the work with the patients, precise observation of the symptoms and syndromes of the diseases in each patient, knowing the most advanced therapy at that time enabled D. Arsov to make conclusion for possibility of new therapy and gave him the material for writing scientific papers. In the first half of the 50s, during his regular work, Arsov discovers a new, internationally recognized therapy for rheumatism. Patients of both Cala-Azar and inflammatory rheumatism were treated with small doses of adrenaline therapy and they felt drastic decrease in rheumatism inflammation within one week. This therapy was used a couple of years in several countries around the world. He participated in the undergraduate and graduate studies. He contributed to the development of 2,240 graduated doctors and under his management over 300 doctors specialized in internal medicine and became specialists internists. Under his management, numerous habilitations and dissertations in internal medicine were finished. He contributed also to the development of 25 assistants, 5 docents, 5 full-time professors in internal medicine at the Medical Faculty in Skopje. He has published more than 200 papers from different areas of internal medicine, of which 36 are on the PubMed. He has published 5 books on internal medicine for students and doctors. He was a President and member of several Macedonian medical associations, as well as of medical associations of former Yugoslavia. He was awarded with the highest awards of former Yugoslavia and Macedonia. He was also awarded with international awards, such as: Doctor Honoris Causa by the University in Besancon and Honor and Medal from the City Assembly of Besancon (France). During his management of the Internal clinic the University Internal clinic developed eight different sub-specialist departments: Cardiology, Pneumology, Rheumatology, Nephrology, Hematology, Gastroenterology and Endocrinology with metabolism and Clinical biochemical laboratory. The fast development of subspecialties has led to development of separate clinics for each subspecialty in 1975, so only the Chair of Internal Medicine remained as a connection between the subspecialties for education and scientific research. He was a prolific scientist who after World War II wrote the first scientific and specialist papers and books in the field of internal medicine in Macedonia. He created a school of internal medicine. The scientific and uncompromised attitude towards the expert truth are weaved in the unforgettable face of the Academician Prof. D-r. Dimitar Arsov, scientist, teacher, and doctor. With his vast work in healing the sick and preventing the diseases in the Republic of Macedonia, he became the cornerstone of modern medicine in the Republic of Macedonia. Thus, he truly deserves to be the doyen of internal medicine, one of the leading, most important persons in medicine of the 20th century in our country. Today, his honorary name appears on: Clinic of Rheumatology at the Medical Faculty in Skopje, Medical Center in Kriva Palanka, Scientific Club of the student organization of the Medical Faculty in Skopje.