Sample records for utilization fine graned

  1. MX Siting Investigation. Mineral Resources Survey, Seven Additional Valleys, Nevada/Utah Siting Area. Volume IV.

    DTIC Science & Technology

    1981-06-23

    Lead, copper , silver In brecciated Devonian (?) limestone at the contact with altered grane* Porphyry (507). Silver, lead, copper , gold. Silver, lead...rhyolite and latite. Molybdenum- quartz yamns and disseminated in quartz monaonilte porphyry ( 402) Silveir, gold, lead, Silver, gold, lead, copper ...in parentheses ) Canyon) Tfungsten, gold. silver Tungsten -irregular pipelike bodies in brocaiated and silicified copper , lead. flourspar liniestone

  2. Ecology of Harmful Algae

    NASA Astrophysics Data System (ADS)

    Roelke, Daniel L.

    2007-07-01

    Edna Graneli and Jefferson T. Turner, Editors;Ecological Studies Series, Vol. 189; Springer; ISBN 3540322094; 413 pp.; 2006; $195 Harmful algal blooms (HABs) affect commercially and recreationally important species, human health, and ecosystem functioning. Hallmark events are the visually stunning blooms where waters are discolored and filled with ichthyotoxin-producing algae that lead to large fish kills. Of most concern, however, are HABs that pose a threat to human health. For example, some phycotoxins bioaccumulate in the guts and tissues of commercially and recreationally important species that when consumed by humans, may result in nausea, paralysis, memory loss, and even death. In addition to the deleterious impacts of phycotoxins, HABs can be problematic in other ways. For example, the decay of blooms often leads to low dissolved oxygen in subsurface waters. Blooms also reduce light penetration into the water column. Both processes disrupt ecosystems and in some cases have completely destroyed benthic communities.

  3. Utilization of the Fine Particles Obtained from Cold Pressed Vegetable Oils: A Case Study in Organic Rice Bran, Sunflower and Sesame Oils.

    PubMed

    Srikaeo, Khongsak; Poungsampao, Phuttan; Phuong, Nguyen Thi

    2017-01-01

    Fine particles obtained from the physical refining of organic cold pressed vegetable oils which are normally discarded as a process waste can be utilized as cosmetic and food ingredients. This paper demonstrated the use of the fine particles from rice bran (Thai Jasmine and Riceberry varieties), sunflower and sesame oils as the ingredient in body mask and as dietary fiber. It was found that the fine particles from rice brans exhibited better antioxidant properties than those of sunflower and sesame. The mixed fine particles were added to body mask formula. The addition of the fine particles affected the physical properties and stability of the body mask especially viscosity and pH. Total dietary fiber recovered from the fine particles ranged from 17.91-23.83 g/100g dry sample. Dietary fiber from Riceberry exhibited the best antioxidant properties as evidenced by DPPH radical scavenging activity and reducing power.

  4. System for utilizing oil shale fines

    DOEpatents

    Harak, Arnold E.

    1982-01-01

    A system is provided for utilizing fines of carbonaceous materials such as particles or pieces of oil shale of about one-half inch or less diameter which are rejected for use in some conventional or prior surface retorting process, which obtains maximum utilization of the energy content of the fines and which produces a waste which is relatively inert and of a size to facilitate disposal. The system includes a cyclone retort (20) which pyrolyzes the fines in the presence of heated gaseous combustion products, the cyclone retort having a first outlet (30) through which vapors can exit that can be cooled to provide oil, and having a second outlet (32) through which spent shale fines are removed. A burner (36) connected to the spent shale outlet of the cyclone retort, burns the spent shale with air, to provide hot combustion products (24) that are carried back to the cyclone retort to supply gaseous combustion products utilized therein. The burner heats the spent shale to a temperature which forms a molten slag, and the molten slag is removed from the burner into a quencher (48) that suddenly cools the molten slag to form granules that are relatively inert and of a size that is convenient to handle for disposal in the ground or in industrial processes.

  5. Relations between Playing Activities and Fine Motor Development

    ERIC Educational Resources Information Center

    Suggate, Sebastian; Stoeger, Heidrun; Pufke, Eva

    2017-01-01

    Children's fine motor skills (FMS) are being increasingly recognized as an important aspect of preschool development; yet, we know very little about the experiences that foster their development. We utilized a parent-administered children's fine and gross motor activities questionnaire (MAQ) to investigate links with FMS. We recruited a sample of…

  6. Construction of Fine Particles Source Spectrum Bank in Typical Region and Empirical Research of Matching Diagnosis

    NASA Astrophysics Data System (ADS)

    Wang, Xing; Sun, Wenliang; Guo, Min; Li, Minjiao; Li, Wan

    2018-01-01

    The research object of this paper is fine particles in typical region. The construction of component spectrum bank is based on the technology of online source apportionment, then the result of the apportionment is utilized to verify the effectiveness of fine particles component spectrum bank and which also act as the matching basis of online source apportionment receptor sample. On the next, the particle source of air pollution is carried through the matching diagnosis empirical research by utilizing online source apportionment technology, to provide technical support for the cause analysis and treatment of heavy pollution weather.

  7. Ground penetrating radar (GPR) detects fine roots of agricultural crops in the field

    Treesearch

    Xiuwei Liu; Xuejun Dong; Qingwu Xue; Daniel I. Leskovar; John Jifon; John R. Butnor; Thomas Marek

    2018-01-01

    Aim Ground penetrating radar (GPR) as a non-invasive technique is widely used in coarse root detection. However, the applicability of the technique to detect fine roots of agricultural crops is unknown. The objective of this study was to assess the feasibility of utilizing GPR to detect fine roots in the field.

  8. The Properties of Mortar Mixtures Blended with Natural, Crushed, and Recycled Fine Aggregates for Building Construction Materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Myoung-Youl; Lee, Jae-Yong; Chung, Chul-Woo

    2012-01-12

    In this research, the possible applicability of fine aggregates blended with natural, crushed, and recycled fine aggregate are discussed. The fresh and hardened properties of mortar using blended fine aggregates are monitored depending on various blending ratio of fine aggregates. Newly developed ternary diagram was also utilized for better interpretation of the data. It was found that air content increased and unit weight decreased as recycled fine aggregate content increased. With moisture type processing of recycled fine aggregate, the mortar flow was not negatively affected by increase in the recycled fine aggregate content. The ternary diagram is found to bemore » an effective graphical presentation tool that can be used for the quality evaluation of mortar using blended fine aggregate.« less

  9. Coarse gaining of molecular crystals: limitations imposed by molecular flexibility

    NASA Astrophysics Data System (ADS)

    Picu, Catalin; Pal, Anirban

    Molecular crystals include molecular electronics, energetic materials, pharmaceuticals and some food components. In many of these applications the small scale mechanical behavior of the crystal is important such as for example in energetic materials where detonation is induced by the formation of hot spots which are induced thermomechanically, and in pharmaceuticals where phase stability is critical for the biochemical activity of the drug. Accurate modeling of these processes requires resolving the atomistic scale details of the material. However, the cost of these models is very large due to the complexity of the molecules forming the crystal, and some form of coarse graning is necessary. In this study we identify the limitations imposed by the need to accurately capture molecular flexibility on the development of coarse grained models for the energetic molecular crystal RDX. We define guidelines for the definition of coarse grained models that target elastic and plastic crystal scale properties such as elastic constants, thermal expansion, compressibility, the critical stress for the motion of dislocations (Peierls stress) and the stacking fault energy This work was supported by the ARO through Grant W911NF-09-1-0330 and AFRL through Grant FA8651-16-1-0004.

  10. Improving the utility of the fine motor skills subscale of the comprehensive developmental inventory for infants and toddlers: a computerized adaptive test.

    PubMed

    Huang, Chien-Yu; Tung, Li-Chen; Chou, Yeh-Tai; Chou, Willy; Chen, Kuan-Lin; Hsieh, Ching-Lin

    2017-07-27

    This study aimed at improving the utility of the fine motor subscale of the comprehensive developmental inventory for infants and toddlers (CDIIT) by developing a computerized adaptive test of fine motor skills. We built an item bank for the computerized adaptive test of fine motor skills using the fine motor subscale of the CDIIT items fitting the Rasch model. We also examined the psychometric properties and efficiency of the computerized adaptive test of fine motor skills with simulated computerized adaptive tests. Data from 1742 children with suspected developmental delays were retrieved. The mean scores of the fine motor subscale of the CDIIT increased along with age groups (mean scores = 1.36-36.97). The computerized adaptive test of fine motor skills contains 31 items meeting the Rasch model's assumptions (infit mean square = 0.57-1.21, outfit mean square = 0.11-1.17). For children of 6-71 months, the computerized adaptive test of fine motor skills had high Rasch person reliability (average reliability >0.90), high concurrent validity (rs = 0.67-0.99), adequate to excellent diagnostic accuracy (area under receiver operating characteristic = 0.71-1.00), and large responsiveness (effect size = 1.05-3.93). The computerized adaptive test of fine motor skills used 48-84% fewer items than the fine motor subscale of the CDIIT. The computerized adaptive test of fine motor skills used fewer items for assessment but was as reliable and valid as the fine motor subscale of the CDIIT. Implications for Rehabilitation We developed a computerized adaptive test based on the comprehensive developmental inventory for infants and toddlers (CDIIT) for assessing fine motor skills. The computerized adaptive test has been shown to be efficient because it uses fewer items than the original measure and automatically presents the results right after the test is completed. The computerized adaptive test is as reliable and valid as the CDIIT.

  11. Steel slag: a waste industrial by-product as an alternative sustainable green building material in construction applications--an attempt for solid waste management.

    PubMed

    Pofale, Arun D; Nadeem, Mohammed

    2012-01-01

    This investigation explores the possibility of utilizing granular slag as an alternative to fine aggregate (natural sand) in construction applications like masonry and plastering. Construction industry utilizes large volume of fine aggregate in all the applications which has resulted into shortage of good quality naturally available fine aggregate. Use of granular slag serves two fold purposes, i.e. waste utilisation as well as alternative eco-friendly green building material for construction. The investigation highlights comparative study of properties with partial and full replacement of fine aggregate (natural sand) by granular slag in cement mortar applications (masonry and plastering). For this purpose, cement mortar mix proportions from 1:3, 1:4, 1:5 & 1:6 by volume were selected for 0, 25, 50, 75 & 100% replacement levels with w/c ratios of 0.60, 0.65, 0.70 & 0.72 respectively. Based on the study results, it could be inferred that replacement of natural sand with granular slag from 25 to 75% increased the packing density of mortar which resulted into reduced w/c ratio, increased strength properties of all mortar mixes. Hence, it could be recommended that the granular slag could be effectively utilized as fine aggregate in masonry and plastering applications in place of conventional cement mortar mixes using natural sand.

  12. Fine grained event processing on HPCs with the ATLAS Yoda system

    NASA Astrophysics Data System (ADS)

    Calafiura, Paolo; De, Kaushik; Guan, Wen; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Tsulaia, Vakhtang; Van Gemmeren, Peter; Wenaus, Torre

    2015-12-01

    High performance computing facilities present unique challenges and opportunities for HEP event processing. The massive scale of many HPC systems means that fractionally small utilization can yield large returns in processing throughput. Parallel applications which can dynamically and efficiently fill any scheduling opportunities the resource presents benefit both the facility (maximal utilization) and the (compute-limited) science. The ATLAS Yoda system provides this capability to HEP-like event processing applications by implementing event-level processing in an MPI-based master-client model that integrates seamlessly with the more broadly scoped ATLAS Event Service. Fine grained, event level work assignments are intelligently dispatched to parallel workers to sustain full utilization on all cores, with outputs streamed off to destination object stores in near real time with similarly fine granularity, such that processing can proceed until termination with full utilization. The system offers the efficiency and scheduling flexibility of preemption without requiring the application actually support or employ check-pointing. We will present the new Yoda system, its motivations, architecture, implementation, and applications in ATLAS data processing at several US HPC centers.

  13. Examining the Potential of Web-Based Multimedia to Support Complex Fine Motor Skill Learning: An Empirical Study

    ERIC Educational Resources Information Center

    Papastergiou, Marina; Pollatou, Elisana; Theofylaktou, Ioannis; Karadimou, Konstantina

    2014-01-01

    Research on the utilization of the Web for complex fine motor skill learning that involves whole body movements is still scarce. The aim of this study was to evaluate the impact of the introduction of a multimedia web-based learning environment, which was targeted at a rhythmic gymnastics routine consisting of eight fine motor skills, into an…

  14. Remediation of negative side effects of an on-going response-cost system with chronic mental patients.

    PubMed

    Doty, D W; McInnis, T; Paul, G L

    1974-01-01

    Response-cost procedures within a token economy with extremely regressed residents excluded many residents from access to positive reinforcement. Procedures allowing residents to "purchase eligibility" to obtain backup reinforcers through contingent payment on standing fines, combined with proportional fine payoff schedules contingent upon time without new fines, increased payment on fines, reduced incidence of new fines, and increased utilization of backup reinforcers. These modifications removed adverse side effects while retaining the benefits associated with response costs. Failures or adverse effects of elements of token systems should not occasion abandonment of token economies, but rather encourage their continual evaluation and modification.

  15. Comparisons of cotton maturity and fineness measurements (Cottonscope, AFIS, HVI™)

    USDA-ARS?s Scientific Manuscript database

    The Cottonscope, a new instrument for fiber maturity (MR) and fineness, utilizes polarized light microscopy and image analysis to measure longitudinal, weighted fiber snippets in water. Interest has been expressed by the Commercial Standardization of Instrument Testing of Cotton (CSITC) on the pote...

  16. Implementation of the use of higher micro-fines in concrete pavements final report.

    DOT National Transportation Integrated Search

    2009-12-01

    The main purpose of this project was to implement previous research performed on concrete utilizing micro-fines : in a field test. The project can be divided into three main parts: First, predetermined materials that were local to : the field trial s...

  17. 31 CFR 206.4 - Collection and payment mechanisms.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... with these criteria, specific cash flows will utilize EFT as follows: (1) Fees/fines. EFT will be adopted as the presumed method of collecting fees and fines, especially when these collection cash flows... provide the Service with a recommended mechanism for any new or modified cash flows. The Service will...

  18. 31 CFR 206.4 - Collection and payment mechanisms.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... with these criteria, specific cash flows will utilize EFT as follows: (1) Fees/fines. EFT will be adopted as the presumed method of collecting fees and fines, especially when these collection cash flows... provide the Service with a recommended mechanism for any new or modified cash flows. The Service will...

  19. 31 CFR 206.4 - Collection and payment mechanisms.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... with these criteria, specific cash flows will utilize EFT as follows: (1) Fees/fines. EFT will be adopted as the presumed method of collecting fees and fines, especially when these collection cash flows... provide the Service with a recommended mechanism for any new or modified cash flows. The Service will...

  20. 31 CFR 206.4 - Collection and payment mechanisms.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... with these criteria, specific cash flows will utilize EFT as follows: (1) Fees/fines. EFT will be adopted as the presumed method of collecting fees and fines, especially when these collection cash flows... provide the Service with a recommended mechanism for any new or modified cash flows. The Service will...

  1. Utilization of AERONET polarimetric measurements for improving retrieval of aerosol microphysics: GSFC, Beijing and Dakar data analysis

    NASA Astrophysics Data System (ADS)

    Fedarenka, Anton; Dubovik, Oleg; Goloub, Philippe; Li, Zhengqiang; Lapyonok, Tatyana; Litvinov, Pavel; Barel, Luc; Gonzalez, Louis; Podvin, Thierry; Crozel, Didier

    2016-08-01

    The study presents the efforts on including the polarimetric data to the routine inversion of the radiometric ground-based measurements for characterization of the atmospheric aerosols and analysis of the obtained advantages in retrieval results. First, to operationally process the large amount of polarimetric data the data preparation tool was developed. The AERONET inversion code adapted for inversion of both intensity and polarization measurements was used for processing. Second, in order to estimate the effect from utilization of polarimetric information on aerosol retrieval results, both synthetic data and the real measurements were processed using developed routine and analyzed. The sensitivity study has been carried out using simulated data based on three main aerosol models: desert dust, urban industrial and urban clean aerosols. The test investigated the effects of utilization of polarization data in the presence of random noise, bias in measurements of optical thickness and angular pointing shift. The results demonstrate the advantage of polarization data utilization in the cases of aerosols with pronounced concentration of fine particles. Further, the extended set of AERONET observations was processed. The data for three sites have been used: GSFC, USA (clean urban aerosol dominated by fine particles), Beijing, China (polluted industrial aerosol characterized by pronounced mixture of both fine and coarse modes) and Dakar, Senegal (desert dust dominated by coarse particles). The results revealed considerable advantage of polarimetric data applying for characterizing fine mode dominated aerosols including industrial pollution (Beijing). The use of polarization corrects particle size distribution by decreasing overestimated fine mode and increasing the coarse mode. It also increases underestimated real part of the refractive index and improves the retrieval of the fraction of spherical particles due to high sensitivity of polarization to particle shape. Overall, the study demonstrates a substantial value of polarimetric data for improving aerosol characterization.

  2. DAILY SIMULATION OF OZONE AND FINE PARTICULATES OVER NEW YORK STATE: FINDINGS AND CHALLENGES

    EPA Science Inventory

    This study investigates the potential utility of the application of a photochemical modeling system in providing simultaneous forecasts of ozone (O3) and fine particulate matter (PM2.5) over New York State. To this end, daily simulations from the Community M...

  3. Phenotypic and genotypic analysis of a U.S. native fine-leaved Festuca population portends its potential use for low-input urban landscapes

    USDA-ARS?s Scientific Manuscript database

    Continued reduction in limited natural resources worldwide increasingly necessitates the incorporation of low maintenance and input plant materials into urban landscapes. Although some fine-leaved Festuca grass species have been utilized in formal gardens and native urban landscapes because of thei...

  4. Hydromulch: a potential use for hardwood bark residue

    Treesearch

    David M. Emanual

    1976-01-01

    Hardwood bark fines and two hardwood bark fibers were compared with wood-cellulose fiber and paper fiber mulch to determine their effectiveness as hydromulches in revegetating disturbed soil. The results showed that either bark fines or bark fibers can be utilized as a hydromulch to aid in the revegetation of strip mines, highway construction sites, and similar earth-...

  5. Demonstrations of the Action and Reaction Law and the Energy Conservation Law Using Fine Spherical Plastic Beads

    ERIC Educational Resources Information Center

    Khumaeni, A.; Tanaka, S.; Kobayashi, A.; Lee, Y. I.; Kurniawan, K. H.; Ishii, K.; Kagawa, K.

    2008-01-01

    Equipment for demonstrating Newton's third law and the energy conservation law in mechanics have successfully been constructed utilizing fine spherical plastic beads in place of metal ball bearings. To demonstrate Newton's third law, special magnetized Petri dishes were employed as objects, while to examine the energy conservation law, a…

  6. Downscaling future climate scenarios to fine scales for hydrologic and ecological modeling and analysis

    USGS Publications Warehouse

    Flint, Lorraine E.; Flint, Alan L.

    2012-01-01

    The methodology, which includes a sequence of rigorous analyses and calculations, is intended to reduce the addition of uncertainty to the climate data as a result of the downscaling while providing the fine-scale climate information necessary for ecological analyses. It results in new but consistent data sets for the US at 4 km, the southwest US at 270 m, and California at 90 m and illustrates the utility of fine-scale downscaling to analyses of ecological processes influenced by topographic complexity.

  7. Multiple Time Series Node Synchronization Utilizing Ambient Reference

    DTIC Science & Technology

    2014-12-31

    assessment, is the need for fine scale synchronization among communicating nodes and across multiple domains. The severe requirements that Special...processing targeted to performance assessment, is the need for fine scale synchronization among communicating nodes and across multiple domains. The...research community and it is well documented and characterized. The datasets considered from this project (listed below) were used to derive the

  8. Introducing close-range photogrammetry for characterizing forest understory plant diversity and surface fuel structure at fine scales

    Treesearch

    Benjamin C. Bright; E. Louise Loudermilk; Scott M. Pokswinski; Andrew T. Hudak; Joseph J. O' Brien

    2016-01-01

    Methods characterizing fine-scale fuels and plant diversity can advance understanding of plant-fire interactions across scales and help in efforts to monitor important ecosystems such as longleaf pine (Pinus palustris Mill.) forests of the southeastern United States. Here, we evaluate the utility of close-range photogrammetry for measuring fuels and plant...

  9. Development of the fine-particle agglomerator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Feldman, P.; Balasic, P.

    1999-07-01

    This paper presents the current status of the commercial development of a new technology to more efficiently control fine particulate emissions. The technology is based on an invention by Environmental Elements Corporation (EEC) which utilizes laminar flow to promote contact of fine submicron particles with larger particles to form agglomerates prior to their removal in a conventional particulate control device, such as an ESP. As agglomerates the particles are easily captured in the control device, whereas a substantial amount would pass through if allowed to remain as fine particles. EEC has developed the laminar-flow agglomerator technology through the laboratory proof-of-conceptmore » stage, which was funded by a DOE SBIR grant, to pilot-scale and full-scale demonstrations.« less

  10. 40 CFR 420.21 - Specialized definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... control system that utilizes filters to remove iron-bearing particles (fines) from blast furnace or... level is 10 pg/L per EPA Method 1613B for water and wastewater samples. (d) The term pg/L means... pollution control system means an emission control system that utilizes water to clean process or furnace...

  11. 40 CFR 420.21 - Specialized definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... control system that utilizes filters to remove iron-bearing particles (fines) from blast furnace or... level is 10 pg/L per EPA Method 1613B for water and wastewater samples. (d) The term pg/L means... pollution control system means an emission control system that utilizes water to clean process or furnace...

  12. 40 CFR 420.21 - Specialized definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... emission control system that utilizes filters to remove iron-bearing particles (fines) from blast furnace...-tetrachlorodibenzofuran, the minimum level is 10 pg/L per EPA Method 1613B for water and wastewater samples. (d) The term... term wet air pollution control system means an emission control system that utilizes water to clean...

  13. 40 CFR 420.21 - Specialized definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... control system that utilizes filters to remove iron-bearing particles (fines) from blast furnace or... level is 10 pg/L per EPA Method 1613B for water and wastewater samples. (d) The term pg/L means... pollution control system means an emission control system that utilizes water to clean process or furnace...

  14. [Hand fine motor skills and use of both hand and arm in subjects after a stroke: a systematic review].

    PubMed

    Ostolaza, M; Abudarham, J; Dilascio, S; Drault-Boedo, E; Gallo, S; Garcete, A; Kramer, M; Maiaru, M; Mendelevich, A; Modica, M; Peralta, F; Sanchez-Correa, C

    2017-04-01

    In clinical practice it is important to be able to assess the function of the upper limb of the patient who has suffered a stroke. There is currently no systemic review that could identify assessment tools for the 'fine use of the hand' and 'use of both hand and arm'. Primary, to identify observational tools which can assess the fine use of the hand and the use of both hand and arm in patients with stroke sequels. Secondary, to analyze the bias risk in the included articles, describing and categorizing the clinical utility, validity and reliability. A search was carried in Medline, LILACS, SciELO and Open Grey, which included articles published until October 2015. Studies that validate assessing tools of the upper limb in subjects with a stroke sequel which evaluate the fine use of the hand and the use of both hand and arm were included. Eleven tools in evaluate observational haven been selected, which assess the fine use of the hand and the use of hand and arm. In every case both validity and reliability have been reported, but clinical utility has been less considered for assessment. The studies that researched these tools showed a high risk of bias in their development. ARAT-19 showed a lower bias risk, but when it has to do with applicability and the reference trial is taken into account, the level of concern is high.

  15. Deep learning-based fine-grained car make/model classification for visual surveillance

    NASA Astrophysics Data System (ADS)

    Gundogdu, Erhan; Parıldı, Enes Sinan; Solmaz, Berkan; Yücesoy, Veysel; Koç, Aykut

    2017-10-01

    Fine-grained object recognition is a potential computer vision problem that has been recently addressed by utilizing deep Convolutional Neural Networks (CNNs). Nevertheless, the main disadvantage of classification methods relying on deep CNN models is the need for considerably large amount of data. In addition, there exists relatively less amount of annotated data for a real world application, such as the recognition of car models in a traffic surveillance system. To this end, we mainly concentrate on the classification of fine-grained car make and/or models for visual scenarios by the help of two different domains. First, a large-scale dataset including approximately 900K images is constructed from a website which includes fine-grained car models. According to their labels, a state-of-the-art CNN model is trained on the constructed dataset. The second domain that is dealt with is the set of images collected from a camera integrated to a traffic surveillance system. These images, which are over 260K, are gathered by a special license plate detection method on top of a motion detection algorithm. An appropriately selected size of the image is cropped from the region of interest provided by the detected license plate location. These sets of images and their provided labels for more than 30 classes are employed to fine-tune the CNN model which is already trained on the large scale dataset described above. To fine-tune the network, the last two fully-connected layers are randomly initialized and the remaining layers are fine-tuned in the second dataset. In this work, the transfer of a learned model on a large dataset to a smaller one has been successfully performed by utilizing both the limited annotated data of the traffic field and a large scale dataset with available annotations. Our experimental results both in the validation dataset and the real field show that the proposed methodology performs favorably against the training of the CNN model from scratch.

  16. Water Utility Lime Sludge Reuse – An Environmental Sorbent for Power Utilities

    EPA Science Inventory

    Lime sludge can be used as an environmental sorbent to remove sulfur dioxide (SO2) and acid gases, by the ultra-fine CaCO3 particles, and to sequester mercury and other heavy metals, by the Natural Organic Matter and residual activated carbon. The laboratory experimental set up ...

  17. Review of the Technology-Utilization Level of String Instrument Teachers

    ERIC Educational Resources Information Center

    Döger, Didem; Kiliç, Ilgim

    2016-01-01

    The purpose of this study is to determine the technology-utilization level of Fine Arts High School string instrument teachers. A pattern based on descriptive method has been used to conduct the researchers. Research data has been collected via literature review and questionnaire developed and prepared by the researcher. SPSS program has been…

  18. Effects of interaural time differences in fine structure and envelope on lateral discrimination in electric hearing.

    PubMed

    Majdak, Piotr; Laback, Bernhard; Baumgartner, Wolf-Dieter

    2006-10-01

    Bilateral cochlear implant (CI) listeners currently use stimulation strategies which encode interaural time differences (ITD) in the temporal envelope but which do not transmit ITD in the fine structure, due to the constant phase in the electric pulse train. To determine the utility of encoding ITD in the fine structure, ITD-based lateralization was investigated with four CI listeners and four normal hearing (NH) subjects listening to a simulation of electric stimulation. Lateralization discrimination was tested at different pulse rates for various combinations of independently controlled fine structure ITD and envelope ITD. Results for electric hearing show that the fine structure ITD had the strongest impact on lateralization at lower pulse rates, with significant effects for pulse rates up to 800 pulses per second. At higher pulse rates, lateralization discrimination depended solely on the envelope ITD. The data suggest that bilateral CI listeners benefit from transmitting fine structure ITD at lower pulse rates. However, there were strong interindividual differences: the better performing CI listeners performed comparably to the NH listeners.

  19. Optimize Operating Conditions on Fine Particle Grinding Process with Vertically Stirred Media Mill

    NASA Astrophysics Data System (ADS)

    Yang, Yang; Rowson, Neil; Ingram, Andy

    2016-11-01

    Stirred media mill recently is commonly utilized among mining process due to its high stressing intensity and efficiency. However, the relationship between size reduction and flow pattern within the mixing pot is still not fully understand. Thus, this work investigates fine particle grinding process within vertically stirred media mills by altering stirrer geometry, tip speed and solids loading. Positron Emitting Particle Tracking (PEPT) technology is utilized to plot routine of particles velocity map. By tacking trajectory of a single particle movement within the mixing vessel, the overall flow pattern is possible to be plotted. Ground calcium carbonate, a main product of Imerys, is chosen as feeding material (feed size D80 30um) mixed with water to form high viscous suspension. To obtain fine size product (normally D80 approximately 2um), large amount of energy is drawn by grinding mill to break particles through impact, shear attrition or compression or a combination of them. The results indicate higher energy efficient is obtained with more dilute suspension. The optimized stirrer proves more energy-saving performance by altering the slurry circulate. Imerys Minerals Limited.

  20. Experimental Study of the Possibility to Make a Mortar with Ternary Sand (Natural and Artificial Fine Aggregates)

    NASA Astrophysics Data System (ADS)

    Baali, L.; Naceri, A.; Rahmouni, Z.; Mehidi, M. W. Noui

    This experimental study investigates the possibility to make a mortar with a ternary sand (natural and artificial fine aggregates). This method is utilized to correct the particle size distribution of various sands used in mortar. For this investigation, three sands have been used: a dune sand (DS), a slag sand (SS), and brick sand (BS) at different proportions in mortar. After crushing, the artificial fine aggregate (blast furnace slag and waste brick fine aggregate) was sifted in order to use it as fine aggregate. The effect of the quality and grain size distribution of natural fine aggregate (i.e., DS) and artificial fine aggregates (i.e., SS and BS) on the physical properties of ternary sand confected (density, porosity, fineness modulus, equivalent sand, particle size distribution, water absorption) and properties of fresh and hardened mortar were analysed. In the same way for this study, the physical properties and chemical compositions of DS, SS, BS and cement were investigated. The results obtained show that the mechanical strength on mortar depends of the nature and particle size distribution of sand studied. The reuse of this recycled material (slag blast furnace and waste brick) in the industry would contribute to the protection of the environment. This study shows the potential of this method to make mortar with ternary sand (natural and artificial fine aggreagates) in order to improve the physical properties of sand. Utilising natural and artificial fine aggregates to produce quality mortar should yield significant environmental benefits.

  1. Development of potassium ion conducting hollow glass fibers. [potassium sulfur battery

    NASA Technical Reports Server (NTRS)

    Tsang, F. Y.

    1974-01-01

    Potassium ion conducting glasses, chemically resistant to potassium, potassium sulfide and sulfur, were made and their possible utility as the membrane material for a potassium/sulfur battery was evaluated. At least one satisfactory candidate was found. It possesses an electrical resistance which makes it usable as a membrane in the form of a fine hollow fiber. It's chemical and electrochemical resistances are excellent. The other aspects of the possible potassium sulfur battery utilizing such fine hollow fibers, including the header (or tube sheet) and a cathode current collector were studied. Several cathode materials were found to be satisfactory. None of the tube sheet materials studied possessed all the desired properties. Multi-fiber cells had very limited life-time due to physical failure of fibers at the fiber/tube sheet junctions.

  2. Air classification: Potential treatment method for optimized recycling or utilization of fine-grained air pollution control residues obtained from dry off-gas cleaning high-temperature processing systems.

    PubMed

    Lanzerstorfer, Christof

    2015-11-01

    In the dust collected from the off-gas of high-temperature processes, usually components that are volatile at the process temperature are enriched. In the recycling of the dust, the concentration of these volatile components is frequently limited to avoid operation problems. Also, for external utilization the concentration of such volatile components, especially heavy metals, is often restricted. The concentration of the volatile components is usually higher in the fine fractions of the collected dust. Therefore, air classification is a potential treatment method to deplete the coarse material from these volatile components by splitting off a fines fraction with an increased concentration of those volatile components. In this work, the procedure of a sequential classification using a laboratory air classifier and the calculations required for the evaluation of air classification for a certain application were demonstrated by taking the example of a fly ash sample from a biomass combustion plant. In the investigated example, the Pb content in the coarse fraction could be reduced to 60% by separation of 20% fines. For the non-volatile Mg the content was almost constant. It can be concluded that air classification is an appropriate method for the treatment of off-gas cleaning residues. © The Author(s) 2015.

  3. Excitonic fine-structure splitting in telecom-wavelength InAs/GaAs quantum dots: Statistical distribution and height-dependence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goldmann, Elias, E-mail: goldmann@itp.uni-bremen.de; Barthel, Stefan; Florian, Matthias

    The variation of the excitonic fine-structure splitting is studied for semiconductor quantum dots under the influence of a strain-reducing layer, utilized to shift the emission wavelength of the excitonic transition into the telecom-wavelength regime of 1.3–1.5 μm. By means of a sp{sup 3}s{sup *}-tight-binding model and configuration interaction, we calculate wavelength shifts and fine-structure splittings for various quantum dot geometries. We find the splittings remaining small and even decreasing with strain-reducing layer composition for quantum dots with large height. Combined with an observed increased emission efficiency, the applicability for generation of entanglement photons is persistent.

  4. THE EFFECT OF WATER CHEMISTRY AND IRON PARTICLE PROPERTIES ON THE REMOVAL OF ARSENIC FOLLOWING THE OXIDATION OF FERROUS IRON

    EPA Science Inventory

    The current MCL for arsenic is being revised to a lower level by the USEPA. Many new utilities, particularly small utilities, will be forced to add an arsenic removal process or fine tune their curent water treatment process to meet the new MCL. Many arsenic removal processes rel...

  5. Coupling fine particle and bedload transport in gravel-bedded streams

    NASA Astrophysics Data System (ADS)

    Park, Jungsu; Hunt, James R.

    2017-09-01

    Fine particles in the silt- and clay-size range are important determinants of surface water quality. Since fine particle loading rates are not unique functions of stream discharge this limits the utility of the available models for water quality assessment. Data from 38 minimally developed watersheds within the United States Geological Survey stream gauging network in California, USA reveal three lines of evidence that fine particle release is coupled with bedload transport. First, there is a transition in fine particle loading rate as a function of discharge for gravel-bedded sediments that does not appear when the sediment bed is composed of sand, cobbles, boulders, or bedrock. Second, the discharge at the transition in the loading rate is correlated with the initiation of gravel mobilization. Third, high frequency particle concentration and discharge data are dominated by clockwise hysteresis where rising limb discharges generally have higher concentrations than falling limb discharges. These three observations across multiple watersheds lead to a conceptual model that fine particles accumulate within the sediment bed at discharges less than the transition and then the gravel bed fluidizes with fine particle release at discharges above the transition discharge. While these observations were individually recognized in the literature, this analysis provides a consistent conceptual model based on the coupling of fine particle dynamics with filtration at low discharges and gravel bed fluidization at higher discharges.

  6. Observations of coastal sediment dynamics of the Tijuana Estuary Fine Sediment Fate and Transport Demonstration Project, Imperial Beach, California

    USGS Publications Warehouse

    Warrick, Jonathan A.; Rosenberger, Kurt J.; Lam, Angela; Ferreiera, Joanne; Miller, Ian M.; Rippy, Meg; Svejkovsky, Jan; Mustain, Neomi

    2012-01-01

    Coastal restoration and management must address the presence, use, and transportation of fine sediment, yet little information exists on the patterns and/or processes of fine-sediment transport and deposition for these systems. To fill this information gap, a number of State of California, Federal, and private industry partners developed the Tijuana Estuary Fine Sediment Fate and Transport Demonstration Project ("Demonstration Project") with the purpose of monitoring the transport, fate, and impacts of fine sediment from beach-sediment nourishments in 2008 and 2009 near the Tijuana River estuary, Imperial Beach, California. The primary purpose of the Demonstration Project was to collect and provide information about the directions, rates, and processes of fine-sediment transport along and across a California beach and nearshore setting. To achieve these goals, the U.S. Geological Survey monitored water, beach, and seafloor properties during the 2008–2009 Demonstration Project. The project utilized sediment with ~40 percent fine sediment by mass so that the dispersal and transport of fine sediment would be easily recognizable. The purpose of this report is to present and disseminate the data collected during the physical monitoring of the Demonstration Project. These data are available online at the links noted in the "Additional Digital Information" section. Synthesis of these data and results will be provided in subsequent publications.

  7. A simulation for gravity fine structure recovery from high-low GRAVSAT SST data

    NASA Technical Reports Server (NTRS)

    Estes, R. H.; Lancaster, E. R.

    1976-01-01

    Covariance error analysis techniques were applied to investigate estimation strategies for the high-low SST mission for accurate local recovery of gravitational fine structure, considering the aliasing effects of unsolved for parameters. Surface density blocks of 5 deg x 5 deg and 2 1/2 deg x 2 1/2 deg resolution were utilized to represent the high order geopotential with the drag-free GRAVSAT configured in a nearly circular polar orbit at 250 km. altitude. GEOPAUSE and geosynchronous satellites were considered as high relay spacecraft. It is demonstrated that knowledge of gravitational fine structure can be significantly improved at 5 deg x 5 deg resolution using SST data from a high-low configuration with reasonably accurate orbits for the low GRAVSAT. The gravity fine structure recoverability of the high-low SST mission is compared with the low-low configuration and shown to be superior.

  8. Characterization and constructive utilization of sludge produced in clari-flocculation unit of water treatment plant

    NASA Astrophysics Data System (ADS)

    Ahmad, Tarique; Ahmad, Kafeel; Alam, Mehtab

    2018-03-01

    All water treatment plants produce waste/residue amid the treatment of raw water. This study selectively investigates the clariflocculator sludge for its physicochemical characteristics and potential reuse options. Sieve analysis, XRF, SEM, XRD, FTIR, and TG-DTA instrumental techniques have been used to characterize the sludge sample. Results show that clariflocculator sludge contains about 78% fine sand having grain size range 150-75 μm. SiO2, Al2O3, Fe2O3 and CaO constitute the maximum percentage of chemical compounds present in the sludge and quartz is the main crystalline phase of the sludge. Recycling and reuse of this sludge, especially, as fine sand in preparing mortar, concrete mix and other civil engineering products would pave the way for constructive utilization with safe and sustainable sludge management strategies.

  9. [Value of ultrasonically-guided liver puncture biopsy in the diagnosis of primary liver cancer. Apropos of 84 cases].

    PubMed

    Peghini, M; Eynard, J P; Vergne, R; Seurat, P; Barabe, P; Aubry, P; Diallo, A; Gueye, P M

    1987-01-01

    Ultrasonographicaly guided fine needle aspiration of liver was performed in 84 patients having a confirmed HCC. This technics utilizes a CHIBA type fine needle, after blood coagulation tests have been checked. Out of 84 fine needle aspirations performed: 64 were positive (76,2%), 9 negative (10,7%), 11 (13,19%) were questionable (6) or nonanalysable (5). It is ascertained that the sensibility of this technics is over 75%. It should be possible to improve it by repeating such an exam in previously negative patients. The causes of failure are discussed. Tolerance of the technics is good. It is attraumatic, and of very easily performance. No accident, no mishap was noted.

  10. Pacific Gas & Electric Plug-In Hybrid Electric Utility Truck Testing |

    Science.gov Websites

    improving efficiency and decreasing emissions during various modes of operation NREL results will help issues and requirements associated with vehicle operation, and fine-tune the design of such vehicles

  11. Spatial downscaling of soil prediction models based on weighted generalized additive models in smallholder farm settings.

    PubMed

    Xu, Yiming; Smith, Scot E; Grunwald, Sabine; Abd-Elrahman, Amr; Wani, Suhas P; Nair, Vimala D

    2017-09-11

    Digital soil mapping (DSM) is gaining momentum as a technique to help smallholder farmers secure soil security and food security in developing regions. However, communications of the digital soil mapping information between diverse audiences become problematic due to the inconsistent scale of DSM information. Spatial downscaling can make use of accessible soil information at relatively coarse spatial resolution to provide valuable soil information at relatively fine spatial resolution. The objective of this research was to disaggregate the coarse spatial resolution soil exchangeable potassium (K ex ) and soil total nitrogen (TN) base map into fine spatial resolution soil downscaled map using weighted generalized additive models (GAMs) in two smallholder villages in South India. By incorporating fine spatial resolution spectral indices in the downscaling process, the soil downscaled maps not only conserve the spatial information of coarse spatial resolution soil maps but also depict the spatial details of soil properties at fine spatial resolution. The results of this study demonstrated difference between the fine spatial resolution downscaled maps and fine spatial resolution base maps is smaller than the difference between coarse spatial resolution base maps and fine spatial resolution base maps. The appropriate and economical strategy to promote the DSM technique in smallholder farms is to develop the relatively coarse spatial resolution soil prediction maps or utilize available coarse spatial resolution soil maps at the regional scale and to disaggregate these maps to the fine spatial resolution downscaled soil maps at farm scale.

  12. High-quality digital color xerography

    NASA Astrophysics Data System (ADS)

    Takiguchi, Koichi

    1993-06-01

    Image noise, tone reproduction, color reproduction, fine line reproduction, and OHP performance are the most important characteristics for a high quality color copier. Technologies enabling such quality are use of fine toner, halftone algorithm to ensure good highlight reproduction, soft roll fuser with good release performance, smooth surface and high thermal conductivity, white and smooth paper, and selection of a coating material for the surface layer of the OHP sheets. These technologies are integrated in the Fuji Xerox `A- Color' product. Utilizing 7 micrometers color toner, `A-Color' can make very high quality color copies.

  13. Our First Quarter Century of Achievement... Just the Beginning

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Space flight, space science, space applications, aeronautics, tracking and data acquisition, international programs, technology utilization, NASA installations, the NASA launch record, astronauts, and the fine arts program are reviewed in light of NASA's 25th anniversary.

  14. The microstructure and properties of rapidly solidified, dispersion-strengthened NiAl

    NASA Technical Reports Server (NTRS)

    Jha, S. C.; Ray, R.

    1990-01-01

    An advanced rapid solidification technology for processing reactive and refractory alloys, utilized to produce large quantities of melt-spun filaments of NiAl, is presented. The melt-spun filaments are pulverized to fine particle sizes, and subsequently consolidated by hot extrusion or hot isostatic pressing. Rapid solidification process gives rise to very fine-grained microstructures. However, exposure to elevated temperature during hot consolidation leads to grain growth. Alloying agents such as borides, carbides, and tungsten can pin the grain boundaries and retard the grain growth. Various alloy compositions are investigated. The eventual goal is to utilize the hot-extruded and forged stock to grow single-crystal NiAl blades for advanced gas-turbine engine applications. Single-crystal NiAl, containing a uniform dispersion of carbide strengthening precipitates, is expected to lead to highly creep-resistant turbine blades, and is of considerable interest to the aerospace propulsion industry.

  15. Insights into metals in individual fine particles from municipal solid waste using synchrotron radiation-based micro-analytical techniques.

    PubMed

    Zhu, Yumin; Zhang, Hua; Shao, Liming; He, Pinjing

    2015-01-01

    Excessive inter-contamination with heavy metals hampers the application of biological treatment products derived from mixed or mechanically-sorted municipal solid waste (MSW). In this study, we investigated fine particles of <2mm, which are small fractions in MSW but constitute a significant component of the total heavy metal content, using bulk detection techniques. A total of 17 individual fine particles were evaluated using synchrotron radiation-based micro-X-ray fluorescence and micro-X-ray diffraction. We also discussed the association, speciation and source apportionment of heavy metals. Metals were found to exist in a diffuse distribution with heterogeneous intensities and intense hot-spots of <10 μm within the fine particles. Zn-Cu, Pb-Fe and Fe-Mn-Cr had significant correlations in terms of spatial distribution. The overlapped enrichment, spatial association, and the mineral phases of metals revealed the potential sources of fine particles from size-reduced waste fractions (such as scraps of organic wastes or ceramics) or from the importation of other particles. The diverse sources of heavy metal pollutants within the fine particles suggested that separate collection and treatment of the biodegradable waste fraction (such as food waste) is a preferable means of facilitating the beneficial utilization of the stabilized products. Copyright © 2014. Published by Elsevier B.V.

  16. Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals.

    PubMed

    Jullesson, David; David, Florian; Pfleger, Brian; Nielsen, Jens

    2015-11-15

    Industrial bio-processes for fine chemical production are increasingly relying on cell factories developed through metabolic engineering and synthetic biology. The use of high throughput techniques and automation for the design of cell factories, and especially platform strains, has played an important role in the transition from laboratory research to industrial production. Model organisms such as Saccharomyces cerevisiae and Escherichia coli remain widely used host strains for industrial production due to their robust and desirable traits. This review describes some of the bio-based fine chemicals that have reached the market, key metabolic engineering tools that have allowed this to happen and some of the companies that are currently utilizing these technologies for developing industrial production processes. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Selection of root-zone media for higher plant cultivation in space.

    PubMed

    Guo, Shuang-sheng; Ai, Wei-dang; Zhao, Cheng-jian; Han, Li-jun; Wang, Jian-xiao

    2004-04-01

    To investigate the cultivating effects of several mineral matters used as root-zone media for higher plant growth in space. Four kinds of artificial and natural mineral matters were used as plant root-zone media based on lots of investigation and analysis. Nutrient liquid was delivered into the media by a long capillary material, and roots of plants obtained nutrition and water from the media. The related parameters such as plant height and photosynthetic efficiency were measured and analyzed. The growing effect in a mixture of coarse and fine ceramic particles with equal quantity proportion was the best, that in fine ceramic particles was the second best, that in clinoptilolite particles was the third and that in diorite particles was the last. The mixture of coarse and fine ceramic particles with equal quantity possesses not only fine capillary action, but also good aerating ability, and therefore is capable of being utilized as an effective root-zone media for higher plants intended to be grown in space.

  18. Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing*

    PubMed Central

    Kowalsky, Caitlin A.; Faber, Matthew S.; Nath, Aritro; Dann, Hailey E.; Kelly, Vince W.; Liu, Li; Shanker, Purva; Wagner, Ellen K.; Maynard, Jennifer A.; Chan, Christina; Whitehead, Timothy A.

    2015-01-01

    Knowledge of the fine location of neutralizing and non-neutralizing epitopes on human pathogens affords a better understanding of the structural basis of antibody efficacy, which will expedite rational design of vaccines, prophylactics, and therapeutics. However, full utilization of the wealth of information from single cell techniques and antibody repertoire sequencing awaits the development of a high throughput, inexpensive method to map the conformational epitopes for antibody-antigen interactions. Here we show such an approach that combines comprehensive mutagenesis, cell surface display, and DNA deep sequencing. We develop analytical equations to identify epitope positions and show the method effectiveness by mapping the fine epitope for different antibodies targeting TNF, pertussis toxin, and the cancer target TROP2. In all three cases, the experimentally determined conformational epitope was consistent with previous experimental datasets, confirming the reliability of the experimental pipeline. Once the comprehensive library is generated, fine conformational epitope maps can be prepared at a rate of four per day. PMID:26296891

  19. Fine pitch thermosonic wire bonding: analysis of state-of-the-art manufacturing capability

    NASA Astrophysics Data System (ADS)

    Cavasin, Daniel

    1995-09-01

    A comprehensive process characterization was performed at the Motorola plastic package assembly site in Selangor, Malaysia, to document the current fine pitch wire bond process capability, using state-of-the-art equipment, in an actual manufacturing environment. Two machines, representing the latest technology from two separate manufacturers, were operated one shift per day for five days, bonding a 132 lead Plastic Quad Flat Pack. Using a test device specifically designed for fine pitch wire bonding, the bonding programs were alternated between 107 micrometers and 92 micrometers pad pitch, running each pitch for a total of 1600 units per machine. Wire, capillary type, and related materials were standardized and commercially available. A video metrology measurement system, with a demonstrated six sigma repeatability band width of 0.51 micrometers , was utilized to measure the bonded units for bond dimensions and placement. Standard Quality Assurance (QA) metrics were also performed. Results indicate that state-of-the-art thermosonic wire bonding can achieve acceptable assembly yields at these fine pad pitches.

  20. Indirect quantification of fine root production in a near tropical wet mountainous region

    NASA Astrophysics Data System (ADS)

    Lu, X.; Zhang, J.; Huang, C.

    2016-12-01

    The main functions of fine root (defined as diameter <= 2 mm) are water and nutrient transports. Besides being a carbon (C) storage pool, it also provides a C flux pathway through soil and plant. Fine root takes up a small portion, normally 5%, of biomass in forest ecosystems, but 30% to 70% of total net primary production. Therefore, quantifying fine root productivity is important to study the forest C budget. Presumably, belowground growth can be indirectly estimated by the more accessible aboveground vegetation structure dynamics. To verify the relationship with fine root productivity, we take internal (floristic) and external (environmental) factors into account, including litter production, canopy density (leaf area index), leaf nutrients (N, K, Ca, Mg, P), weather and/or soil physical conditions (air temperature, humidity, precipitation, solar radiation and soil moisture). The study was conducted in near tropical broadleaf (700 m asl) and conifer (1700 m asl) forests in northeastern Taiwan, generally receiving more than 4000 mm of precipitation per year. For each site, 16 50-cm long minirhizotron tubes were installed. Fine root images were acquired every three weeks. Growth and decline, newly presence and absence of fine roots were delineated by image processing algorithms to derive fine-root productivity through time. Aforementioned internal and external attributes were simultaneously collected as well. Some of these variables were highly correlated and were detrended using principal component analysis. We found that these transformed variables (mainly associated with litter production, precipitation and solar radiation) can delineate the spatiotemporal dynamics of root production well (r2 = 0.87, p = 0.443). In conclusion, this study demonstrated the feasibility of utilized aboveground variables to indirectly assess fine root growth, which could be further developed for the regional scale mapping with aid of remote sensing.

  1. Method of feeding particulate material to a fluidized bed

    DOEpatents

    Borio, Richard W.; Goodstine, Stephen L.

    1984-01-01

    A centrifugal spreader type feeder that supplies a mixture of particulate limestone and coal to the top of a fluidized bed reactor having a flow of air upward therethrough. Large particles of particulate matter are distributed over the upper surface of the bed to utilize the natural mixing within the bed, while fine particles are adapted to utilize an independent feeder that separates them from the large particles and injects them into the bed.

  2. Gd uptake experiments for preliminary set of functionalized adsorbents

    DOE Data Explorer

    Clinton Noack

    2015-03-16

    These data summarize adsorption experiments conducted with Gd in 0.5 M NaCl. Results represent preliminary, proof-of-concept data utilizing fine-powder silica gel as the adsorbent support. Future testing will focus on larger, application-appropriate beads.

  3. Laser-assisted solar cell metallization processing

    NASA Technical Reports Server (NTRS)

    Dutta, S.

    1984-01-01

    Laser-assisted processing techniques utilized to produce the fine line, thin metal grid structures that are required to fabricate high efficiency solar cells are examined. Two basic techniques for metal deposition are investigated; (1) photochemical decomposition of liquid or gas phase organometallic compounds utilizing either a focused, CW ultraviolet laser (System 1) or a mask and ultraviolet flood illumination, such as that provided by a repetitively pulsed, defocused excimer laser (System 2), for pattern definition, and (2) thermal deposition of metals from organometallic solutions or vapors utilizing a focused, CW laser beam as a local heat source to draw the metallization pattern.

  4. Multielement mapping of alpha-SiC by scanning Auger microscopy

    NASA Technical Reports Server (NTRS)

    Browning, Ray; Smialek, James L.; Jacobson, Nathan S.

    1987-01-01

    Fine second-phase particles, numerous in sintered alpha-SiC, were analyzed by scanning Auger microscopy and conventional techniques. The Auger analysis utilized computer-controlled data acquisition, multielement correlation diagrams, and a high spatial resolution of 100 nm. This procedure enabled construction of false color maps and the detection of fine compositional details within these particles. Carbon, silicon oxide, and boron-rich particles (qualitatively as BN or B4C) predominated. The BN particles, sometimes having a carbon core, are believed to result from reaction between B4C additives and nitrogen sintering atmospheres.

  5. Laser-assisted solar cell metallization processing

    NASA Technical Reports Server (NTRS)

    Dutta, S.

    1984-01-01

    Laser assisted processing techniques utilized to produce the fine line, thin metal grid structures that are required to fabricate high efficiency solar cells are investigated. The tasks comprising these investigations are summarized. Metal deposition experiments are carried out utilizing laser assisted pyrolysis of a variety of metal bearing polymer films and metalloorganic inks spun onto silicon substrates. Laser decomposition of spun on silver neodecanoate ink yields very promising results. Solar cell comb metallization patterns are written using this technique.

  6. Survey Report on Cooper River, S.C. (Shoaling in Charleston Harbor), Appendix A, Supplement 3. Special Geological Investigations Utilizing Diagnostic Minerals.

    DTIC Science & Technology

    CLAY, COASTAL REGIONS, CYCLES, DELTAS, DEPOSITION, DIAGNOSIS(GENERAL), FINES, FLOW, GEOLOGY, GEOMORPHOLOGY, KAOLINITE , MATHEMATICAL MODELS, MINERALS...MODELS, MONTMORILLONITE , PARAMETERS, PETROGRAPHY, PROCESSING, RATIOS, RESIDUALS, RESPONSE, RIVERS, SALINITY, SAMPLING, SAND, SCHIST, SEDIMENTS

  7. Gd uptake experiments for preliminary set of functionalized adsorbents (with content model)

    DOE Data Explorer

    Clinton Noack

    2015-03-16

    These data summarize adsorption experiments conducted with Gd in 0.5 M NaCl. Results represent preliminary, proof-of-concept data utilizing fine-powder silica gel as the adsorbent support. Future testing will focus on larger, application-appropriate beads.

  8. Reverse transcriptase polymerase chain reaction on fine needle aspirates for rapid detection of translocations in synovial sarcoma.

    PubMed

    Nilsson, G; Wang, M; Wejde, J; Kanter, L; Karlén, J; Tani, E; Kreicbergs, A; Larsson, O

    1998-01-01

    To evaluate the utilization of fine needle aspiration (FNA) biopsy to obtain material for reverse-transcriptase polymerase chain reaction (RT-PCR) in the detection of the t(X;18)(p11.2;q11.2) translocation in synovial sarcomas. We applied RT-PCR to detection of synovial sarcoma fusion gene transcripts on fine needle aspirates. Five clinical samples were first analyzed: one was a tumor previously diagnosed as malignant hemangiopericytoma, one was a poorly defined tumor, and three were suspected synovial sarcomas. FNA material was transferred directly to the RT-PCR reaction tube without RNA extraction. The t(X;18) translocation could be detected on the limited amount of material that FNA provides. In each of the cases studied the representivity of the tumor samples was confirmed microscopically. Our protocol permits analysis directly on representative samples without extraction of RNA. The results imply that RT-PCR offers reliable detection of sarcoma fusion gene transcripts on fine needle aspirates. The procedure, apart from being applicable to outpatients, is rapid and sensitive.

  9. Role of metals in free radical generation and genotoxicity induced by airborne particulate matter (PM2.5) from Pune (India).

    PubMed

    Yadav, Suman; Jan, Rohi; Roy, Ritwika; Satsangi, P Gursumeeran

    2016-12-01

    In the present study, metal-facilitated free radical generation in particulate matter (PM) and its association with deoxyribonucleic acid (DNA) damage were studied. The examined data showed that the concentration of fine PM in Pune exhibited seasonal variations. Inductively coupled plasma-atomic emission spectrometry (ICP-AES) was used to examine the metal composition, which showed the presence of metals such as Cu, Zn, Mn, Fe, Co, Cr, Pb, Cd, and Ni. Fe metal was present in the highest concentrations in both the seasons, followed by Zn. The scanning electron microscopy-energy-dispersive spectrometer (SEM-EDS) results also demonstrated that the fine PM particles deposited in summer samples were less than those of winter samples, suggesting that the PM load in winter was higher as compared to that in summer. Elemental mapping of these particles substantiates deposition of metals as Fe, Zn, etc. on particles. The electron paramagnetic species (EPR) technique was utilized for free radical detection, and plasmid DNA assay was utilized to study the genotoxicity of ambient fine PM. Obtained g values show the presence of radicals in PM samples of Pune. PM contains the C-centered radical with a vicinal oxygen atom (g = 2.003). In addition to this, the g value for Fe was also observed. Therefore, we intend that the radicals related with fine PM comprise metal-mediated radicals and produce DNA damage. The plasmid DNA assay results indicated that the TM 50 values (toxic mass of PM causing 50 % of plasmid DNA damage) of PM exhibited seasonal variations with higher TM 50 values for summer and lower TM 50 values during winter.

  10. HYDROCARBON OXIDATION OVER VANADIUM PHOSPHORUS OXIDE CATALYST USING HYDROGEN PEROXIDE

    EPA Science Inventory

    Selective oxidation of hydrocarbons is one of the very important and challenging areas in industrial chemistry due to the wide ranging utility of the resulting oxygenates in fine chemical synthesis. Most of the existing processes for their oxidations employ toxic and often stoich...

  11. Dance Critique as Signature Pedagogy

    ERIC Educational Resources Information Center

    Kearns, Lauren

    2017-01-01

    The curriculum of preprofessional university degree programs in dance typically comprise four components: theory and history, dance technique, creative process, and performance. This article focuses on critique in the modern dance technique and choreography components of the dance curriculum. Bachelor of Fine Arts programs utilize critique as a…

  12. Demonstration of a Balloon Borne Arc-second Pointer Design

    NASA Astrophysics Data System (ADS)

    Deweese, K.; Ward, P.

    Many designs for utilizing stratospheric balloons as low-cost platforms on which to conduct space science experiments have been proposed throughout the years A major hurdle in extending the range of experiments for which these vehicles are useful has been the imposition of the gondola dynamics on the accuracy with which an instrument can be kept pointed at a celestial target A significant number of scientists have sought the ability to point their instruments with jitter in the arc-second range This paper presents the design and analysis of a stratospheric balloon borne pointing system that is able to meet this requirement The test results of a demonstration prototype of the design with similar ability are also presented Discussion of a high fidelity controller simulation for design analysis is presented The flexibility of the flight train is represented through generalized modal analysis A multiple controller scheme is utilized for coarse and fine pointing Coarse azimuth pointing is accomplished by an established pointing system with extensive flight history residing above the gondola structure A pitch-yaw gimbal mount is used for fine pointing providing orthogonal axes when nominally on target Fine pointing actuation is from direct drive dc motors eliminating backlash problems An analysis of friction nonlinearities and a demonstration of the necessity in eliminating static friction are provided A unique bearing hub design is introduced that eliminates static friction from the system dynamics A control scheme involving linear

  13. A fine structure genetic analysis evaluating ecoregional adaptability of a Bos taurus breed (Hereford)

    USDA-ARS?s Scientific Manuscript database

    Ecoregional differences contribute to genetic environmental interactions and impact animal performance. These differences may become more important under climate change scenarios. Utilizing genetic diversity within a species to address such problems has not been fully explored. In this study Herefor...

  14. Utilizing 1-meter Landcover Data to Assess Associations between Green Space and Stress

    EPA Science Inventory

    Purpose: When using remotely-sensed data to study health, researchers must identify an appropriate spatial resolution to capture potential exposures. Investigations into urban green space are often limited by the unavailability of fine-scale landcover data. We analyzed 1-meter gr...

  15. 41 CFR 102-39.60 - What restrictions and prohibitions apply to the exchange/sale of personal property?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... code of scrap, as defined at FMR 102-36.40, except: (1) Property that had utility and value at the... disaster); or (3) Scrap gold for fine gold. (f) Property that was originally acquired as excess or...

  16. 41 CFR 102-39.60 - What restrictions and prohibitions apply to the exchange/sale of personal property?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... code of scrap, as defined at FMR 102-36.40, except: (1) Property that had utility and value at the... disaster); or (3) Scrap gold for fine gold. (f) Property that was originally acquired as excess or...

  17. 41 CFR 102-39.60 - What restrictions and prohibitions apply to the exchange/sale of personal property?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... code of scrap, as defined at FMR 102-36.40, except: (1) Property that had utility and value at the... disaster); or (3) Scrap gold for fine gold. (f) Property that was originally acquired as excess or...

  18. Evaluating the Fine Arts Program at the Center for Excellence in Disabilities

    ERIC Educational Resources Information Center

    Schlosnagle, Leo; McBean, Amanda L.; Cutlip, Milisa; Panzironi, Helen; Jarmolowicz, David P.

    2014-01-01

    Art programs for people with disabilities may encourage creativity, promote engagement, emphasize inclusion, and extend access and opportunities for community involvement. This mixed methods study utilized quantitative and qualitative data, repeated measures, action research, and stakeholder collaboration to develop and implement an evaluation…

  19. Assessment of Near-Source Air Pollution at a Fine Spatial Scale Utilizing Mobile Monitoring Approach

    EPA Science Inventory

    Mobile monitoring is an emerging strategy to characterize spatially and temporally variable air pollution in areas near sources. EPA’s Geospatial Monitoring of Air Pollution (GMAP) vehicle – an all-electric vehicle measuring real-time concentrations of partic...

  20. Design of experimental studies of human performance under influences of simulated artificial gravity. [effects of rotation on psychomotor tasks

    NASA Technical Reports Server (NTRS)

    Piland, W. M.; Hausch, H. G.; Maraman, G. V.; Green, J. A.

    1973-01-01

    A ground based research program is now being undertaken to provide data concerning the effects of a rotating environment on man's ability to adequately perform gross and fine psychomotor tasks. Emphasis is being placed on establishing the levels of artificial gravity and rates and radii of rotation required in future space systems for preservation of crew performance and comfort. An experimental study utilizing a rotational facility to investigate crew mobility, cargo transfer and handling, and fine motor coordination at radii up to 24 meters and at rotational rates up to 5 rpm is reported.

  1. Small-Grid Dithers for the JWST Coronagraphs

    NASA Technical Reports Server (NTRS)

    Lajoie, Charles-Philippe; Soummer, Remi; Pueyo, Laurent; Hines, Dean C.; Nelan, Edmund P.; Perrin, Marshall; Clampin, Mark; Isaacs, John C.

    2016-01-01

    We discuss new results of coronagraphic simulations demonstrating a novel mode for JWST that utilizes sub-pixel dithered reference images, called Small-Grid Dithers, to optimize coronagraphic PSF subtraction. These sub-pixel dithers are executed with the Fine Steering Mirror under fine guidance, are accurate to approx.2-3 milliarcseconds (1-s/axis), and provide ample speckle diversity to reconstruct an optimized synthetic reference PSF using LOCI or KLIP. We also discuss the performance gains of Small-Grid Dithers compared to the standard undithered scenario, and show potential contrast gain factors for the NIRCam and MIRI coronagraphs ranging from 2 to more than 10, respectively.

  2. Wavefront Sensing with the Fine Guidance Sensor for James Webb Space Telescope

    NASA Technical Reports Server (NTRS)

    Smith, J. Scott; Aronstein, David; Dean, Bruce H.; Howard,Joe; Shiri, Ron

    2008-01-01

    An analysis is presented that utilizes the Fine Guidance Sensor (FGS) for focal-plane wavefront sensing (WFS) for the James Webb Space Telescope (JWST). WFS with FGS increases the number of wavefront measurements taken in field of the telescope, but has many challenges over the other JWST instruments that make it unique, such as; less sampling of the Point Spread Function (PSF), a smaller diversity-defocus range, a smaller image detector size, and a polychromatic object or source. Additionally, presented is an analysis of sampling for wavefront sensing. Results are shown based on simulations of flight and the cryogenic optical testing at NASA Johnson Space Center.

  3. Fine-pitched microgratings encoded by interference of UV femtosecond laser pulses.

    PubMed

    Kamioka, Hayato; Miura, Taisuke; Kawamura, Ken-ichi; Hirano, Masahiro; Hosono, Hideo

    2002-01-01

    Fine-pitched microgratings are encoded on fused silica surfaces by a two-beam laser interference technique employing UV femtosecond pulses from the third harmonics of a Ti:sapphire laser. A pump and prove method utilizing a laser-induced optical Kerr effect or transient optical absorption change has been developed to achieve the time coincidence of the two pulses. Use of the UV pulses makes it possible to narrow the grating pitches to an opening as small as 290 nm, and the groove width of the gratings is of nanoscale size. The present technique provides a novel opportunity for the fabrication of periodic nanoscale structures in various materials.

  4. Comparison: Discovery on WSMOLX and miAamics/jABC

    NASA Astrophysics Data System (ADS)

    Kubczak, Christian; Vitvar, Tomas; Winkler, Christian; Zaharia, Raluca; Zaremba, Maciej

    This chapter compares the solutions to the SWS-Challenge discovery problems provided by DERI Galway and the joint solution from the Technical University of Dortmund and University of Postdam. The two approaches are described in depth in Chapters 10 and 13. The discovery scenario raises problems associated with making service discovery an automated process. It requires fine-grained specifications of search requests and service functionality including support for fetching dynamic information during the discovery process (e.g., shipment price). Both teams utilize semantics to describe services, service requests and data models in order to enable search at the required fine-grained level of detail.

  5. The utility of satellite observations for constraining fine-scale and transient methane sources

    NASA Astrophysics Data System (ADS)

    Turner, A. J.; Jacob, D.; Benmergui, J. S.; Brandman, J.; White, L.; Randles, C. A.

    2017-12-01

    Resolving differences between top-down and bottom-up emissions of methane from the oil and gas industry is difficult due, in part, to their fine-scale and often transient nature. There is considerable interest in using atmospheric observations to detect these sources. Satellite-based instruments are an attractive tool for this purpose and, more generally, for quantifying methane emissions on fine scales. A number of instruments are planned for launch in the coming years from both low earth and geostationary orbit, but the extent to which they can provide fine-scale information on sources has yet to be explored. Here we present an observation system simulation experiment (OSSE) exploring the tradeoffs between pixel resolution, measurement frequency, and instrument precision on the fine-scale information content of a space-borne instrument measuring methane. We use the WRF-STILT Lagrangian transport model to generate more than 200,000 column footprints at 1.3×1.3 km2 spatial resolution and hourly temporal resolution over the Barnett Shale in Texas. We sub-sample these footprints to match the observing characteristics of the planned TROPOMI and GeoCARB instruments as well as different hypothetical observing configurations. The information content of the various observing systems is evaluated using the Fisher information matrix and its singular values. We draw conclusions on the capabilities of the planned satellite instruments and how these capabilities could be improved for fine-scale source detection.

  6. Enhancing of chemical compound and drug name recognition using representative tag scheme and fine-grained tokenization.

    PubMed

    Dai, Hong-Jie; Lai, Po-Ting; Chang, Yung-Chun; Tsai, Richard Tzong-Han

    2015-01-01

    The functions of chemical compounds and drugs that affect biological processes and their particular effect on the onset and treatment of diseases have attracted increasing interest with the advancement of research in the life sciences. To extract knowledge from the extensive literatures on such compounds and drugs, the organizers of BioCreative IV administered the CHEMical Compound and Drug Named Entity Recognition (CHEMDNER) task to establish a standard dataset for evaluating state-of-the-art chemical entity recognition methods. This study introduces the approach of our CHEMDNER system. Instead of emphasizing the development of novel feature sets for machine learning, this study investigates the effect of various tag schemes on the recognition of the names of chemicals and drugs by using conditional random fields. Experiments were conducted using combinations of different tokenization strategies and tag schemes to investigate the effects of tag set selection and tokenization method on the CHEMDNER task. This study presents the performance of CHEMDNER of three more representative tag schemes-IOBE, IOBES, and IOB12E-when applied to a widely utilized IOB tag set and combined with the coarse-/fine-grained tokenization methods. The experimental results thus reveal that the fine-grained tokenization strategy performance best in terms of precision, recall and F-scores when the IOBES tag set was utilized. The IOBES model with fine-grained tokenization yielded the best-F-scores in the six chemical entity categories other than the "Multiple" entity category. Nonetheless, no significant improvement was observed when a more representative tag schemes was used with the coarse or fine-grained tokenization rules. The best F-scores that were achieved using the developed system on the test dataset of the CHEMDNER task were 0.833 and 0.815 for the chemical documents indexing and the chemical entity mention recognition tasks, respectively. The results herein highlight the importance of tag set selection and the use of different tokenization strategies. Fine-grained tokenization combined with the tag set IOBES most effectively recognizes chemical and drug names. To the best of the authors' knowledge, this investigation is the first comprehensive investigation use of various tag set schemes combined with different tokenization strategies for the recognition of chemical entities.

  7. MROrchestrator: A Fine-Grained Resource Orchestration Framework for MapReduce Clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sharma, Bikash; Prabhakar, Ramya; Kandemir, Mahmut

    2012-01-01

    Efficient resource management in data centers and clouds running large distributed data processing frameworks like MapReduce is crucial for enhancing the performance of hosted applications and boosting resource utilization. However, existing resource scheduling schemes in Hadoop MapReduce allocate resources at the granularity of fixed-size, static portions of nodes, called slots. In this work, we show that MapReduce jobs have widely varying demands for multiple resources, making the static and fixed-size slot-level resource allocation a poor choice both from the performance and resource utilization standpoints. Furthermore, lack of co-ordination in the management of mul- tiple resources across nodes prevents dynamic slotmore » reconfigura- tion, and leads to resource contention. Motivated by this, we propose MROrchestrator, a MapReduce resource Orchestrator framework, which can dynamically identify resource bottlenecks, and resolve them through fine-grained, co-ordinated, and on- demand resource allocations. We have implemented MROrches- trator on two 24-node native and virtualized Hadoop clusters. Experimental results with a suite of representative MapReduce benchmarks demonstrate up to 38% reduction in job completion times, and up to 25% increase in resource utilization. We further show how popular resource managers like NGM and Mesos when augmented with MROrchestrator can hike up their performance.« less

  8. Chemical Upcycling of Expired Drugs: Synthesis of Guaifenesin Acetonide

    ERIC Educational Resources Information Center

    Barcena, Homar; Maziarz, Katarzyna

    2017-01-01

    In an effort to repurpose expired guaifenesin tablets, experiments devised for practical instruction are reported for the preparation and isolation of the guaifenesin acetonide using a microscale kit. The laboratory experiment successfully utilizes a waste chemical in lieu of a fine chemical to illustrate the principles behind protecting groups in…

  9. Assessment of Near-Source Air Pollution at a Fine Spatial Scale Utilizing Mobile Monitoring Approach

    EPA Science Inventory

    Mobile monitoring is an emerging strategy to characterize spatially and temporally variable air pollution in areas near sources. EPA’s Geospatial Monitoring of Air Pollution (GMAP) vehicle – an all-electric vehicle measuring real-time concentrations of particulate and gaseous po...

  10. Refining the Eye: Dermatology and Visual Literacy

    ERIC Educational Resources Information Center

    Zimmermann, Corinne; Huang, Jennifer T.; Buzney, Elizabeth A.

    2016-01-01

    In 2014 the Museum of Fine Arts Boston and Harvard Medical School began a partnership focused on building visual literacy skills for dermatology residents in the Harvard Combined Dermatology Residency Program. "Refining the Eye: Art and Dermatology", a four session workshop, took place in the museum's galleries and utilized the Visual…

  11. Assessment of Near-Source Air Pollution at a Fine Spatial Scale Utilizing a Mobile Monitoring Approach

    EPA Science Inventory

    Mobile monitoring is an emerging strategy to characterize spatially and temporally variable air pollution in areas near sources. EPA’s Geospatial Monitoring of Air Pollution (GMAP) vehicle – an all-electric vehicle measuring real-time concentrations of particulate and gaseous po...

  12. Assessment of near-source air pollution at a fine spatial scale utilizing a mobile measurement platform approach

    EPA Science Inventory

    Mobile monitoring is an emerging strategy to characterize spatially and temporally variable air pollution in areas near sources. EPA’s Geospatial Monitoring of Air Pollution (GMAP) vehicle, an all-electric vehicle measuring real-time concentrations of particulate and gaseous poll...

  13. Beneficial use of classified paper waste for training land rehabilitation

    USDA-ARS?s Scientific Manuscript database

    This project will demonstrate and validate utilization of pulverized waste paper as an organic soil amendment for rehabilitation of disturbed training lands. Large quantities of classified documents are landfilled by the Department of Defense (DoD) since they have been pulverized too finely to be re...

  14. Uses for Sawdust, Shavings, And Waste Chips

    Treesearch

    J. M. Harkin

    1969-01-01

    Although many outlets are available for the utilization of wood fines, economical disposal of sawdust, shavings, and waste chips remains a problem of growing concern to the wood industry. This report summarizes current uses for wood residues and provides sources of further information on available outlets, processing methods, and economic considerations.

  15. Kinematic performance of fine motor control in attention-deficit/hyperactivity disorder: the effects of comorbid developmental coordination disorder and core symptoms.

    PubMed

    Lee, I-Ching; Chen, Yung-Jung; Tsai, Chin-Liang

    2013-02-01

    The aims of this study were: (i) to determine whether differences exist in the fine motor fluency and flexibility of three groups (children with attention-deficit/hyperactivity disorder [ADHD], children in whom ADHD is comorbid with developmental coordination disorder [DCD] [denoted as ADHD+DCD], and a typically developing control group); and (ii) to clarify whether the degree of severity of core symptoms affects performance. The Peabody Picture Vocabulary Test-Revised, the Beery-Buktenica Development Test of Visual-Motor Integration and the Movement Assessment Battery for Children were used as prescreening tests. The Integrated Visual and Auditory+Plus test was utilized to assess subjects' attention. The redesigned fine motor tracking and pursuit tasks were administered to evaluate subjects' fine motor performance. No significant difference was found when comparing the performance of the Children with ADHD and the typically developing group. Significant differences existed between children in whom ADHD is comorbid with DCD and typically developing children. Children with ADHD demonstrated proper fine motor fluency and flexibility, and deficient performance occurred when ADHD was comorbid with developmental coordination disorder. Children with ADHD had more difficulty implementing closed-loop movements that required higher levels of cognitive processing than those of their typically developing peers. Also, deficits in fine motor control were more pronounced when ADHD was combined with movement coordination problems. The severity of core symptoms had a greater effect on children with ADHD's fine motor flexibility than did fluency performance. In children with pure ADHD, unsmooth movement performance was highly related to the severity of core symptoms. © 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.

  16. Resistance spot welding of ultra-fine grained steel sheets produced by constrained groove pressing: Optimization and characterization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khodabakhshi, F.; Kazeminezhad, M., E-mail: mkazemi@sharif.edu; Kokabi, A.H.

    2012-07-15

    Constrained groove pressing as a severe plastic deformation method is utilized to produce ultra-fine grained low carbon steel sheets. The ultra-fine grained sheets are joined via resistance spot welding process and the characteristics of spot welds are investigated. Resistance spot welding process is optimized for welding of the sheets with different severe deformations and their results are compared with those of as-received samples. The effects of failure mode and expulsion on the performance of ultra-fine grained sheet spot welds have been investigated in the present paper and the welding current and time of resistance spot welding process according to thesemore » subjects are optimized. Failure mode and failure load obtained in tensile-shear test, microhardness, X-ray diffraction, transmission electron microscope and scanning electron microscope images have been used to describe the performance of spot welds. The region between interfacial to pullout mode transition and expulsion limit is defined as the optimum welding condition. The results show that optimum welding parameters (welding current and welding time) for ultra-fine grained sheets are shifted to lower values with respect to those for as-received specimens. In ultra-fine grained sheets, one new region is formed named recrystallized zone in addition to fusion zone, heat affected zone and base metal. It is shown that microstructures of different zones in ultra-fine grained sheets are finer than those of as-received sheets. - Highlights: Black-Right-Pointing-Pointer Resistance spot welding process is optimized for joining of UFG steel sheets. Black-Right-Pointing-Pointer Optimum welding current and time are decreased with increasing the CGP pass number. Black-Right-Pointing-Pointer Microhardness at BM, HAZ, FZ and recrystallized zone is enhanced due to CGP.« less

  17. Development of fine motor skills is associated with expressive language outcomes in infants at high and low risk for autism spectrum disorder.

    PubMed

    Choi, Boin; Leech, Kathryn A; Tager-Flusberg, Helen; Nelson, Charles A

    2018-04-12

    A growing body of research suggests that fine motor abilities are associated with skills in a variety of domains in both typical and atypical development. In this study, we investigated developmental trajectories of fine motor skills between 6 and 24 months in relation to expressive language outcomes at 36 months in infants at high and low familial risk for autism spectrum disorder (ASD). Participants included 71 high-risk infants without ASD diagnoses, 30 high-risk infants later diagnosed with ASD, and 69 low-risk infants without ASD diagnoses. As part of a prospective, longitudinal study, fine motor skills were assessed at 6, 12, 18, and 24 months of age and expressive language outcomes at 36 months using the Mullen Scales of Early Learning. Diagnosis of ASD was determined at the infant's last visit to the lab (18, 24, or 36 months) using the Autism Diagnostic Observation Schedule. Hierarchical linear modeling revealed that high-risk infants who later developed ASD showed significantly slower growth in fine motor skills between 6 and 24 months, compared to their typically developing peers. In contrast to group differences in growth from age 6 months, cross-sectional group differences emerged only in the second year of life. Also, fine motor skills at 6 months predicted expressive language outcomes at 3 years of age. These results highlight the importance of utilizing longitudinal approaches in measuring early fine motor skills to reveal subtle group differences in infancy between ASD high-risk and low-risk infant populations and to predict their subsequent language outcomes.

  18. Risks on N-acetyltransferase 2 and bladder cancer: a meta-analysis.

    PubMed

    Zhu, Zongheng; Zhang, Jinshan; Jiang, Wei; Zhang, Xianjue; Li, Youkong; Xu, Xiaoming

    2015-01-01

    It is known that bladder cancer disease is closely related to aromatic amine compounds, which could cause cancer by regulating of N-acetylation and N-acetyltransferase 1 and 2 (NAT1 and NAT2). The NAT2 slowed acetylation and would increase the risk of bladder cancer, with tobacco smoke being regarded as a risk factor for this increased risk. However, the relationship between NAT2 slow acetylation and bladder cancer is still debatable at present. This study aims to explore preliminarily correlation of NAT2 slow acetylation and the risk of bladder cancer. The articles were searched from PubMed, Cochran, McGrane English databases, CBM, CNKI, and other databases. The extraction of bladder cancer patients and a control group related with the NAT2 gene were detected by the state, and the referenced articles and publications were also used for data retrieval. Using a random effects model, the model assumes that the studies included in the analysis cases belong to the overall population in the study of random sampling, and considering the variables within and between studies. Data were analyzed using STATA Version 6.0 software, using the META module. According to the inclusion and exclusion criteria of the literature study, 20 independent studies are included in this meta-analysis. The results showed that the individual differences of bladder cancer susceptibility might be part of the metabolism of carcinogens. Slow acetylation status of bladder cancer associated with the pooled odds ratio was 1.31 (95% confidence interval: 1.11-1.55). The status of NAT2 slow N-acetylation is associated with bladder cancer risks, and may increase the risk of bladder cancer.

  19. The neurological work of Artur Galcerán i Granés (1850-1919).

    PubMed

    Arboix, A; Fabregas, M G

    2011-05-01

    To analyze the neurological work of Artur Galcerán i Granés (Girona 1850-Barcelona 1919) founder of the Society of Psychiatry and Neurology of Barcelona in 1911. We performed a literature search using MEDLINE from the keywords"Galceran Granés" and "Society of Psychiatry and Neurology of Barcelona", using the doctoral thesis of M. G. Fabregas Camps: "History of Neurology in Catalonia. From 1882 to 1949 ", and original historical bibliographical sources of the Library of the Academy of Sciences Mèdiques de Catalunya i Balears. Artur Galcerán i Granés was a disciple of the school of psychiatry of Dr. Joan Giné i Partagàs. His highlighting neurological work was: 1) "Some static and dynamic inferences about the brain, which may serve to clarify the concept of localization", 2) "Treatment of epilepsy" and 3) "Neuropathology and General Psychiatry". He was editor of "Archivos de Terapeútica de las enfermedades nerviosas y mentales" and "Anales de la Sociedad de Psiquiatría y Neurología". He was director of the mental asylum in Sant Boi of Llobregat and Pere Mata of Reus. In 1911 he founded the first Catalan and Spanish neurological society in Barcelona. The neurological work of Artur Galcerán i Granes is remarkable and significant. He was the founder of the first Catalan and Spanish neurological society: The Society of Psychiatry and Neurology of Barcelona in 1911, the forerunner of the Catalan Society of Neurology. Copyright © 2010 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  20. Models of compacted fine-grained soils used as mineral liner for solid waste

    NASA Astrophysics Data System (ADS)

    Sivrikaya, Osman

    2008-02-01

    To prevent the leakage of pollutant liquids into groundwater and sublayers, the compacted fine-grained soils are commonly utilized as mineral liners or a sealing system constructed under municipal solid waste and other containment hazardous materials. This study presents the correlation equations of the compaction parameters required for construction of a mineral liner system. The determination of the characteristic compaction parameters, maximum dry unit weight ( γ dmax) and optimum water content ( w opt) requires considerable time and great effort. In this study, empirical models are described and examined to find which of the index properties correlate well with the compaction characteristics for estimating γ dmax and w opt of fine-grained soils at the standard compactive effort. The compaction data are correlated with different combinations of gravel content ( G), sand content ( S), fine-grained content (FC = clay + silt), plasticity index ( I p), liquid limit ( w L) and plastic limit ( w P) by performing multilinear regression (MLR) analyses. The obtained correlations with statistical parameters are presented and compared with the previous studies. It is found that the maximum dry unit weight and optimum water content have a considerably good correlation with plastic limit in comparison with liquid limit and plasticity index.

  1. Spectral structure and stability studies on microstructure-fiber continuum

    NASA Astrophysics Data System (ADS)

    Gu, Xun; Kimmel, Mark; Zeek, Erik; Shreenath, Aparna P.; Trebino, Rick P.; Windeler, Robert S.

    2003-07-01

    Although previous direct measurements of the microstructure-fiber continuum have all showed a smooth and stable spectrum, our cross-correlation frequency-resolved optical gating (XFROG) full-intensity-and-phase characterization of the continuum pulse, utilizing sum-frequency-generation with a pre-characterized reference pulse and the angle-dithered-crystal technique, indicates that fine-scale spectral structure exists on a single-shot basis, contrary to previous observations. In particular, deep and fine oscillations are found in the retrieved spectrum, and the retrieved trace contains a "measles" pattern, whereas the measured trace and the independently-measured spectrum are rather smooth. The discrepancy is shown to be the result of unstable single-shot spectral structure. Although the XFROG measurement is not able to directly measure the single-shot fine structure in the trace, the redundancy of information in FROG traces enables the retrieval algorithm to correctly recognize the existence of the spectral fine structure, and restore the structure in the retrieved trace and spectrum. Numerical simulations have supported our hypothesis, and we directly observed the fine spectral structure in single-shot measurements of the continuum spectrum and the structure was seen to be highly unstable, the continuum spectrum appearing smooth only when many shots are averaged. Despite the structure and instability in the continuum spectrum, coherence experiments also reveal that the spectral phase is rather stable, being able to produce well-defined spectral fringes across the entire continuum bandwidth.

  2. Development of a spatio-temporal disaggregation method (DisNDVI) for generating a time series of fine resolution NDVI images

    NASA Astrophysics Data System (ADS)

    Bindhu, V. M.; Narasimhan, B.

    2015-03-01

    Normalized Difference Vegetation Index (NDVI), a key parameter in understanding the vegetation dynamics, has high spatial and temporal variability. However, continuous monitoring of NDVI is not feasible at fine spatial resolution (<60 m) owing to the long revisit time needed by the satellites to acquire the fine spatial resolution data. Further, the study attains significance in the case of humid tropical regions of the earth, where the prevailing atmospheric conditions restrict availability of fine resolution cloud free images at a high temporal frequency. As an alternative to the lack of high resolution images, the current study demonstrates a novel disaggregation method (DisNDVI) which integrates the spatial information from a single fine resolution image and temporal information in terms of crop phenology from time series of coarse resolution images to generate estimates of NDVI at fine spatial and temporal resolution. The phenological variation of the pixels captured at the coarser scale provides the basis for relating the temporal variability of the pixel with the NDVI available at fine resolution. The proposed methodology was tested over a 30 km × 25 km spatially heterogeneous study area located in the south of Tamil Nadu, India. The robustness of the algorithm was assessed by an independent comparison of the disaggregated NDVI and observed NDVI obtained from concurrent Landsat ETM+ imagery. The results showed good spatial agreement across the study area dominated with agriculture and forest pixels, with a root mean square error of 0.05. The validation done at the coarser scale showed that disaggregated NDVI spatially averaged to 240 m compared well with concurrent MODIS NDVI at 240 m (R2 > 0.8). The validation results demonstrate the effectiveness of DisNDVI in improving the spatial and temporal resolution of NDVI images for utility in fine scale hydrological applications such as crop growth monitoring and estimation of evapotranspiration.

  3. Utilization of blended fluidized bed combustion (FBC) ash and pulverized coal combustion (PCC) fly ash in geopolymer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chindaprasirt, Prinya; Rattanasak, Ubolluk, E-mail: ubolluk@buu.ac.t

    2010-04-15

    In this paper, synthesis of geopolymer from fluidized bed combustion (FBC) ash and pulverized coal combustion (PCC) fly ash was studied in order to effectively utilize both ashes. FBC-fly ash and bottom ash were inter-ground to three different finenesses. The ashes were mixed with as-received PCC-fly ash in various proportions and used as source material for synthesis of geopolymer. Sodium silicate (Na{sub 2}SiO{sub 3}) and 10 M sodium hydroxide (NaOH) solutions at mass ratio of Na{sub 2}SiO{sub 3}/NaOH of 1.5 and curing temperature of 65 deg. C for 48 h were used for making geopolymer. X-ray diffraction (XRD), scanning electronmore » microscopy (SEM), degree of reaction, and thermal gravimetric analysis (TGA) were performed on the geopolymer pastes. Compressive strength was also tested on geopolymer mortars. The results show that high strength geopolymer mortars of 35.0-44.0 MPa can be produced using mixture of ground FBC ash and as-received PCC-fly ash. Fine FBC ash is more reactive and results in higher degree of reaction and higher strength geopolymer as compared to the use of coarser FBC ash. Grinding increases reactivity of ash by means of increasing surface area and the amount of reactive phase of the ash. In addition, the packing effect due to fine particles also contributed to increase in strength of geopolymers.« less

  4. A novel crystallization technique of hydroxyapatite utilizing contact reaction of minute droplet with atmospheric plasmas: Effects of the liquid source composition on the produced crystal properties

    NASA Astrophysics Data System (ADS)

    Wada, Y.; Kobayashi, T.; Matsumoto, M.; Onoe, K.

    2017-10-01

    To develop the technique for the control of the crystal composition and properties such as size distribution and morphology utilizing the contact reaction field around the minute droplets in atmospheric pressure plasma, fine spherical particles of hydroxyapatite ((Ca10(PO4)6(OH)2); HAp) were synthesized by a new plasma crystallization method. In this work, to elucidate the effects of the production region and crystal properties of hydroxyapatite for the liquid source composition, Ca2+ concentration and the Ca/P molar ratio in minute droplets were varied. The following results were obtained: (1) fine spherical HAp particles can be produced by the introduction of minute droplets with the initial Ca2+ concentration ((CCa)0) of 0.50 mol/l and the Ca/P molar ratio of 1.67. (2) When the (CCa)0 is set in the range higher than 1.00 mol/l at the constant Ca/P molar ratio of 1.67, fine spherical particles of β-TCP and HAp mixture are crystallized. (3) For the Ca/P molar ratio below 1.67, α-TCP and HAp co-precipitated. (4) The composition of the produced particles depends on both the reactant concentration and Ca/P molar ratio in the HAp source solution. (5) The dependence of the reactant concentration on the average size of the produced HAp particles is large compared with droplet size.

  5. Insight into Factors Affecting the Presence, Degree, and Temporal Stability of Fluorescence Intensification on ZnO Nanorod Ends

    PubMed Central

    Singh, Manpreet; Jiang, Ruibin; Coia, Heidi; Choi, Daniel S.; Alabanza, Anginelle; Chang, Jae Young; Wang, Jianfang; Hahm, Jong-in

    2014-01-01

    We have carried out a combined experimental and simulation study identifying the key physical and optical parameters affecting the presence and degree of fluorescence intensification measured on zinc oxide nanorod (ZnO NR) ends. Previously, we reported on the highly localized, intensified, and prolonged fluorescence signal measured on the NR ends, termed as fluorescence intensification on NR ends (FINE). As a step towards understanding the mechanism of FINE, the present study aims to provide an insight into the unique optical phenomenon of FINE through experimental and simulation approaches and to elucidate the key factors affecting the occurrence, degree, and temporal stability of FINE. Specifically, we examined the effect of the length, width, and growth orientation of single ZnO NRs on the NR-enhanced biomolecular emission profile after decorating the NR surfaces with different amounts and types of fluorophore-coupled protein molecules. We quantitatively and qualitatively profiled the biomolecular fluorescence signal from individual ZnO NRs as a function of both position along the NR long axis and time. Regardless of the physical dimensions and growth orientations of the NRs, we confirmed the presence of FINE from all ZnO NRs tested by using a range of protein concentrations. We also showed that the manifestation of FINE is not dependent on the spectroscopic signatures of the fluorophores employed. We further observed that the degree of FINE is dependent on the length of the NR with longer NRs showing increased levels of FINE. We also demonstrated that vertically oriented NRs exhibit much stronger fluorescence intensity at the NR ends and a higher level of FINE than the laterally oriented NRs. Additionally, we employed finite-difference time-domain (FDTD) methods to understand the experimental outcomes and to promote our understanding of the mechanism of FINE. Particularly, we utilized the electrodynamic simulations to examine both near-field and far-field emission characteristics when considering various scenarios of fluorophore locations, polarizations, spectroscopic characteristics, and NR dimensions. Our efforts may provide a deeper insight into the unique optical phenomenon of FINE and further be beneficial to highly miniaturized biodetection favoring the use of single ZnO NRs in low-volume and high-throughput protein assays. PMID:25504319

  6. CROSS-CULTURAL COMMUNICATION AND DRAMATIC RITUAL.

    ERIC Educational Resources Information Center

    SALISBURY, LEE H.

    THE AUTHOR'S PROGRAM, COLLEGE ORIENTATION PROGRAM FOR ALASKAN NATIVES (COPAN), WAS DEVELOPED TO PROVIDE A SMOOTH TRANSITION FOR NATIVE ALASKAN STUDENTS INTO THE AREA OF WESTERN CULTURE, IN COLLEGE. THE FINE ARTS WERE UTILIZED AS A COMMUNICATION BRIDGE BETWEEN THE ESKIMO AND WESTERN CULTURES. THE MEDIA OF THE DANCE AND DRAMA WERE THE BASES FOR…

  7. "Pack[superscript2]": VM Resource Scheduling for Fine-Grained Application SLAs in Highly Consolidated Environment

    ERIC Educational Resources Information Center

    Sukwong, Orathai

    2013-01-01

    Virtualization enables the ability to consolidate multiple servers on a single physical machine, increasing the infrastructure utilization. Maximizing the ratio of server virtual machines (VMs) to physical machines, namely the consolidation ratio, becomes an important goal toward infrastructure cost saving in a cloud. However, the consolidation…

  8. Preference uncertainty, preference learning, and paired comparison experiments

    Treesearch

    David C. Kingsley; Thomas C. Brown

    2010-01-01

    Results from paired comparison experiments suggest that as respondents progress through a sequence of binary choices they become more consistent, apparently fine-tuning their preferences. Consistency may be indicated by the variance of the estimated valuation distribution measured by the error term in the random utility model. A significant reduction in the variance is...

  9. Elementary Forms of Cosmopolitanism: Blood, Birth, and Bodies in Immigrant New York City

    ERIC Educational Resources Information Center

    Kromidas, Maria

    2011-01-01

    In this article, Maria Kromidas explores how nine-, ten-, and eleven-year-old children in a diverse neighborhood school in immigrant New York City navigated and often undermined hegemonic notions of difference and belonging offered by mainstream multiculturalism and raciology. Based on ethnographic research and utilizing a fine-grained…

  10. FIELD EVALUATION OF A HIGH-VOLUME DICHOTOMOUS SAMPLER

    EPA Science Inventory

    This study presents the field evaluation of a high-volume dichotomous sampler that collects coarse (PM10-2.5) and fine (PM2.5) particulate matter. The key feature of this device is the utilization of a round-nozzle virtual impactor with a 50% cutpoint at 2.5 5m to split PM10 into...

  11. Industrial waste utilization for foam concrete

    NASA Astrophysics Data System (ADS)

    Krishnan, Gokul; Anand, K. B.

    2018-02-01

    Foam concrete is an emerging and useful construction material - basically a cement based slurry with at least 10% of mix volume as foam. The mix usually containing cement, filler (usually sand) and foam, have fresh densities ranging from 400kg/m3 to 1600kg/m3. One of the main drawbacks of foam concrete is the large consumption of fine sand as filler material. Usage of different solid industrial wastes as fillers in foam concrete can reduce the usage of fine river sand significantly and make the work economic and eco-friendly. This paper aims to investigate to what extent industrial wastes such as bottom ash and quarry dust can be utilized for making foam concrete. Foam generated using protein based agent was used for preparing and optimizing (fresh state properties). Investigation to find the influence of design density and air-void characteristics on the foam concrete strength shows higher strength for bottom ash mixes due to finer air void distribution. Setting characteristics of various mix compositions are also studied and adoption of Class C flyash as filler demonstrated capability of faster setting.

  12. Therapeutic aspects of endoscopic ultrasound

    NASA Astrophysics Data System (ADS)

    Woodward, Timothy A.

    1999-06-01

    Endoscopic ultrasound (EUS) is a technology that had been used primarily as a passive imaging modality. Recent advances have enabled us to move beyond the use of EUS solely as a staging tool to an interventional device. Current studies suggest that interventional applications of EUS will allow for minimally invasive assessment and therapies in a cost-effective manner. Endoscopic ultrasound with fine needle aspiration (EUS-FNA) has been demonstrated to be a technically feasible, relatively safe method of obtaining cytologic specimens. The clinical utility of EUS- FNA appears to be greatest in the diagnosis and staging of pancreatic cancer and in the nodal staging of gastrointestinal and pulmonary malignancies. In addition, EUS-FNA has demonstrated utility in the sampling pleural and ascitic fluid not generally appreciated or assessable to standard interventions. Interventional applications of EUS include EUS-guided pseudocyst drainage, EUS-guided injection of botulinum toxin in the treatment of achalasia, and EUS- guided celiac plexus neurolysis in the treatment of pancreatic cancer pain. Finally, EUS-guided fine-needle installation is being evaluated, in conjunction with recent bimolecular treatment modalities, as a delivery system in the treatment of certain gastrointestinal tumors.

  13. Avoiding space robot collisions utilizing the NASA/GSFC tri-mode skin sensor

    NASA Technical Reports Server (NTRS)

    Prinz, F. B. S.; Mahalingam, S.

    1992-01-01

    A capacitance based proximity sensor, the 'Capaciflector' (Vranish 92), has been developed at the Goddard Space Flight Center of NASA. We had investigated the use of this sensor for avoiding and maneuvering around unexpected objects (Mahalingam 92). The approach developed there would help in executing collision-free gross motions. Another important aspect of robot motion planning is fine motion planning. Let us classify manipulator robot motion planning into two groups at the task level: gross motion planning and fine motion planning. We use the term 'gross planning' where the major degrees of freedom of the robot execute large motions, for example, the motion of a robot in a pick and place type operation. We use the term 'fine motion' to indicate motions of the robot where the large dofs do not move much, and move far less than the mirror dofs, such as in inserting a peg in a hole. In this report we describe our experiments and experiences in this area.

  14. Particulates and fine dust removal: processes and equipment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sittig, M.

    1977-01-01

    Particulates and fine dust created by man's activities contribute significantly to all major aspects of air pollution. While the generation of natural fine dusts is also very large in some parts of the earth, industrially generated, particle-loaded air emissions may push the particulate level to a point where acceptable air quality standards are exceeded continuously. How to reduce such emissions at the source, and what processes and equipment to use, is the subject of this book, which is based on reports of federally-financed air pollution studies as well as U.S. patents. Following an introduction with an overview of industrial particulatemore » emissions, emission data and emission control processes are discussed for the following specific industries: airlines; asphalt; cement; coal; electric utilities; ferrous metals; fertilizer; food; forest products; paper; chemicals; nonferrous metals; nuclear; petroleum refining; stone and clay; and textiles. Conventional and innovative particle removal devices are described. The disposal of collected particles is discussed. The economic and energy consumption aspects of particulate control are presented. (LCL)« less

  15. Efficient design of nanoplasmonic waveguide devices using the space mapping algorithm.

    PubMed

    Dastmalchi, Pouya; Veronis, Georgios

    2013-12-30

    We show that the space mapping algorithm, originally developed for microwave circuit optimization, can enable the efficient design of nanoplasmonic waveguide devices which satisfy a set of desired specifications. Space mapping utilizes a physics-based coarse model to approximate a fine model accurately describing a device. Here the fine model is a full-wave finite-difference frequency-domain (FDFD) simulation of the device, while the coarse model is based on transmission line theory. We demonstrate that simply optimizing the transmission line model of the device is not enough to obtain a device which satisfies all the required design specifications. On the other hand, when the iterative space mapping algorithm is used, it converges fast to a design which meets all the specifications. In addition, full-wave FDFD simulations of only a few candidate structures are required before the iterative process is terminated. Use of the space mapping algorithm therefore results in large reductions in the required computation time when compared to any direct optimization method of the fine FDFD model.

  16. Changes in gross grasp strength and fine motor skills in adolescents with pediatric multiple sclerosis.

    PubMed

    Squillace, Mary; Ray, Sharon; Milazzo, Maria

    2015-01-01

    This study examined the gross grasp strength and fine motor dexterity of adolescents, who are diagnosed with multiple sclerosis (MS). A total sample size of 72 participants between the ages of 13 to 17 was studied. Thirty six with a diagnosis of pediatric relapse remitting MS and 36 matched control participants were selected from various local youth groups. Data on hand strength and dexterity was collected using a dynamometer, nine hole peg board and Purdue pegboard on both groups. Utilizing ANCOVA to describe the differences across the two groups by diagnosis, controlling for age and gender, it was found that the MS group demonstrated significantly decreased dexterity when compared to age and gender matched controls. There was no significant difference in gross grasp strength by diagnostic group. This preliminary study showed that children with a diagnosis of pediatric MS may have differences in fine motor dexterity, but not gross grasp strength from their peers who do not have the diagnosis. Further study is indicated to examine this phenomenon.

  17. A High-Frequency Linear Ultrasonic Array Utilizing an Interdigitally Bonded 2-2 Piezo-Composite

    PubMed Central

    Cannata, Jonathan M.; Williams, Jay A.; Zhang, Lequan; Hu, Chang-Hong; Shung, K. Kirk

    2011-01-01

    This paper describes the development of a high-frequency 256-element linear ultrasonic array utilizing an interdigitally bonded (IB) piezo-composite. Several IB composites were fabricated with different commercial and experimental piezoelectric ceramics and evaluated to determine a suitable formulation for use in high-frequency linear arrays. It was found that the fabricated fine-scale 2–2 IB composites outperformed 1–3 IB composites with identical pillar- and kerf-widths. This result was not expected and lead to the conclusion that dicing damage was likely the cause of the discrepancy. Ultimately, a 2–2 composite fabricated using a fine-grain piezoelectric ceramic was chosen for the array. The composite was manufactured using one IB operation in the azimuth direction to produce approximately 19-μm-wide pillars separated by 6-μm-wide kerfs. The array had a 50 μm (one wavelength in water) azimuth pitch, two matching layers, and 2 mm elevation length focused to 7.3 mm using a polymethylpentene (TPX) lens. The measured pulse-echo center frequency for a representative array element was 28 MHz and −6-dB band-width was 61%. The measured single-element transmit −6-dB directivity was estimated to be 50°. The measured insertion loss was 19 dB after compensating for the effects of attenuation and diffraction in the water bath. A fine-wire phantom was used to assess the lateral and axial resolution of the array when paired with a prototype system utilizing a 64-channel analog beamformer. The −6-dB lateral and axial resolutions were estimated to be 125 and 68 μm, respectively. An anechoic cyst phantom was also imaged to determine the minimum detectable spherical inclusion, and thus the 3-D resolution of the array and beamformer. The minimum anechoic cyst detected was approximately 300 μm in diameter. PMID:21989884

  18. Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations

    PubMed Central

    Yoneyama, Sachiko; Yao, Jie; Guo, Xiuqing; Fernandez-Rhodes, Lindsay; Lim, Unhee; Boston, Jonathan; Buzková, Petra; Carlson, Christopher S.; Cheng, Iona; Cochran, Barbara; Cooper, Richard; Ehret, Georg; Fornage, Myriam; Gong, Jian; Gross, Myron; Gu, C. Charles; Haessler, Jeff; Haiman, Christopher A.; Henderson, Brian; Hindorff, Lucia A.; Houston, Denise; Irvin, Marguerite R.; Jackson, Rebecca; Kuller, Lew; Leppert, Mark; Lewis, Cora E.; Li, Rongling; Le Marchand, Loic; Matise, Tara C.; Nguyen, Khanh-Dung H.; Chakravarti, Aravinda; Pankow, James S.; Pankratz, Nathan; Pooler, Loreall; Ritchie, Marylyn D.; Bien, Stephanie A.; Wassel, Christina L.; Chen, Yii-Der I.; Taylor, Kent D.; Allison, Matthew; Rotter, Jerome I.; Schreiner, Pamela J.; Schumacher, Fredrick; Wilkens, Lynne; Boerwinkle, Eric; Kooperberg, Charles; Peters, Ulrike; Buyske, Steven; Graff, Mariaelisa; North, Kari E.

    2016-01-01

    Background/Objectives Central adiposity measures such as waist circumference (WC) and waist-to-hip ratio (WHR) are associated with cardiometabolic disorders independently of BMI and are gaining clinically utility. Several studies report genetic variants associated with central adiposity, but most utilize only European ancestry populations. Understanding whether the genetic associations discovered among mainly European descendants are shared with African ancestry populations will help elucidate the biological underpinnings of abdominal fat deposition. Subjects/Methods To identify the underlying functional genetic determinants of body fat distribution, we conducted an array-wide association meta-analysis among persons of African ancestry across seven studies/consortia participating in the Population Architecture using Genomics and Epidemiology (PAGE) consortium. We used the Metabochip array, designed for fine mapping cardiovascular associated loci, to explore novel array-wide associations with WC and WHR among 15 945 African descendants using all and sex-stratified groups. We further interrogated 17 known WHR regions for African ancestry-specific variants. Results Of the 17 WHR loci, eight SNPs located in four loci were replicated in the sex-combined or sex-stratified meta-analyses. Two of these eight independently associated with WHR after conditioning on the known variant in European descendants (rs12096179 in TBX15-WARS2 and rs2059092 in ADAMTS9). In the fine mapping assessment, the putative functional region was reduced across all four loci but to varying degrees (average 40% drop in number of putative SNPs and 20% drop in genomic region). Similar to previous studies, the significant SNPs in the female stratified analysis were stronger than the significant SNPs from the sex-combined analysis. No novel associations were detected in the array-wide analyses. Conclusions Of 17 previously identified loci, four loci replicated in the African ancestry populations of this study. Utilizing different linkage disequilibrium patterns observed between European and African ancestries, we narrowed the suggestive region containing causative variants for all four loci. PMID:27867202

  19. Utilization of recycled glass derived from cathode ray tube glass as fine aggregate in cement mortar.

    PubMed

    Ling, Tung-Chai; Poon, Chi-Sun

    2011-08-30

    Rapid advances in the electronic industry led to an excessive amount of early disposal of older electronic devices such as computer monitors and old televisions (TV) before the end of their useful life. The management of cathode ray tubes (CRT), which have been a key component in computer monitors and TV sets, has become a major environmental problem worldwide. Therefore, there is a pressing need to develop sustainable alternative methods to manage hazardous CRT glass waste. This study assesses the feasibility of utilizing CRT glass as a substitute for natural aggregates in cement mortar. The CRT glass investigated was an acid-washed funnel glass of dismantled CRT from computer monitors and old TV sets. The mechanical properties of mortar mixes containing 0%, 25%, 50%, 75% and 100% of CRT glass were investigated. The potential of the alkali-silica reaction (ASR) and leachability of lead were also evaluated. The results confirmed that the properties of the mortar mixes prepared with CRT glass was similar to that of the control mortar using sand as fine aggregate, and displayed innocuous behaviour in the ASR expansion test. Incorporating CRT glass in cement mortar successfully prevented the leaching of lead. We conclude that it is feasible to utilize CRT glass in cement mortar production. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. DAILY SIMULATIONS OF OZONE AND FINE PARTICULATES OVER THE NORTHEASTERN UNITED STATES: MODEL PERFORMANCE, SEASONAL DIFFERENCES, AND THE EFFECT OF MODEL UPDATES

    EPA Science Inventory

    This poster presents analysis of near-realtime air quality simulations over New York State for two summer and one winter season. Simulations were performed as a pilot study between the NOAA, EPA, and NYSDEC, utilizing resources from the national operational NOAA/EPA air quality f...

  1. Calcium silicate insulation structure

    DOEpatents

    Kollie, Thomas G.; Lauf, Robert J.

    1995-01-01

    An insulative structure including a powder-filled evacuated casing utilizes a quantity of finely divided synthetic calcium silicate having a relatively high surface area. The resultant structure-provides superior thermal insulating characteristics over a broad temperature range and is particularly well-suited as a panel for a refrigerator or freezer or the insulative barrier for a cooler or a insulated bottle.

  2. Utilization of oak residues

    Treesearch

    Richard C. Allison

    1971-01-01

    Residues should be thought of as a raw material for specific uses rather than as a waste. Fines and solid wood residues are usually kept separated in waste-collection system, but species are rarely kept separated. The properties of each species dictate what uses can be made of them. Quantity, location, cost, moisture content, physical size, and presence of foreign...

  3. A hierarchical spatial framework for forest landscape planning.

    Treesearch

    Pete Bettinger; Marie Lennette; K. Norman Johnson; Thomas A. Spies

    2005-01-01

    A hierarchical spatial framework for large-scale, long-term forest landscape planning is presented along with example policy analyses for a 560,000 ha area of the Oregon Coast Range. The modeling framework suggests utilizing the detail provided by satellite imagery to track forest vegetation condition and for representation of fine-scale features, such as riparian...

  4. COMPARATIVE EVALUATION OF R3f GARNET BEAD FILTRATION AND MULTIMEDIA FILTRATION SYSTEMS; FINAL REPORT

    EPA Science Inventory

    This report summarizes the results of tests conducted to date at the EPA T&E Facility on the R3f filtration system utilizing fine beads (such as garnet beads or glass beads) and a conventional multimedia filtration system. Both systems have been designed and built by Enprotec, a...

  5. Managing fine hardwoods after a half century of research: Proceedings of the Seventh Walnut Council Research Symposium

    Treesearch

    J.W. Van Sambeek; Elizabeth A. Jackson; Mark V. Coggeshall; Andrew L. Thomas; Charles H. eds. Michler

    2013-01-01

    This report presents information from the Seventh Walnut Council Research Symposium, held August 1-3, 2011. This report includes 14 papers and abstracts relating to economics and utilization, pest management, nursery production, plantation establishment, tree improvement, stand management, agroforestry, and nut production of black walnut, related Juglans species, and...

  6. Factors Affecting Sensitivity to Frequency Change in School-Age Children and Adults

    ERIC Educational Resources Information Center

    Buss, Emily; Taylor, Crystal N.; Leibold, Lori J.

    2014-01-01

    Purpose: The factors affecting frequency discrimination in school-age children are poorly understood. The goal of the present study was to evaluate developmental effects related to memory for pitch and the utilization of temporal fine structure. Method: Listeners were 5.1- to 13.6-year-olds and adults, all with normal hearing. A subgroup of…

  7. Advanced particulate matter control apparatus and methods

    DOEpatents

    Miller, Stanley J [Grand Forks, ND; Zhuang, Ye [Grand Forks, ND; Almlie, Jay C [East Grand Forks, MN

    2012-01-10

    Apparatus and methods for collection and removal of particulate matter, including fine particulate matter, from a gas stream, comprising a unique combination of high collection efficiency and ultralow pressure drop across the filter. The apparatus and method utilize simultaneous electrostatic precipitation and membrane filtration of a particular pore size, wherein electrostatic collection and filtration occur on the same surface.

  8. Char binder for fluidized beds

    DOEpatents

    Borio, Richard W.; Accortt, Joseph I.

    1981-01-01

    An arrangement that utilizes agglomerating coal as a binder to bond coal fines and recycled char into an agglomerate mass that will have suitable retention time when introduced into a fluidized bed 14 for combustion. The simultaneous use of coal for a primary fuel and as a binder effects significant savings in the elimination of non-essential materials and processing steps.

  9. Climatological Aspects of the Optical Properties of Fine/Coarse Mode Aerosol Mixtures

    NASA Technical Reports Server (NTRS)

    Eck, T. F.; Holben, B. N.; Sinyuk, A.; Pinker, R. T.; Goloub, P.; Chen, H.; Chatenet, B.; Li, Z.; Singh, R. P.; Tripathi, S.N.; hide

    2010-01-01

    Aerosol mixtures composed of coarse mode desert dust combined with fine mode combustion generated aerosols (from fossil fuel and biomass burning sources) were investigated at three locations that are in and/or downwind of major global aerosol emission source regions. Multiyear monitoring data at Aerosol Robotic Network sites in Beijing (central eastern China), Kanpur (Indo-Gangetic Plain, northern India), and Ilorin (Nigeria, Sudanian zone of West Africa) were utilized to study the climatological characteristics of aerosol optical properties. Multiyear climatological averages of spectral single scattering albedo (SSA) versus fine mode fraction (FMF) of aerosol optical depth at 675 nm at all three sites exhibited relatively linear trends up to 50% FMF. This suggests the possibility that external linear mixing of both fine and coarse mode components (weighted by FMF) dominates the SSA variation, where the SSA of each component remains relatively constant for this range of FMF only. However, it is likely that a combination of other factors is also involved in determining the dynamics of SSA as a function of FMF, such as fine mode particles adhering to coarse mode dust. The spectral variation of the climatological averaged aerosol absorption optical depth (AAOD) was nearly linear in logarithmic coordinates over the wavelength range of 440-870 nm for both the Kanpur and Ilorin sites. However, at two sites in China (Beijing and Xianghe), a distinct nonlinearity in spectral AAOD in logarithmic space was observed, suggesting the possibility of anomalously strong absorption in coarse mode aerosols increasing the 870 nm AAOD.

  10. Responses to prospective payment by rural New Mexico hospitals.

    PubMed

    Smith, H L; Piland, N F; Phillipp, A M

    1991-12-01

    A cross-sectional study is used to determine how rural New Mexico hospitals altered service diversification, inpatient service emphasis, and service promotion during Medicare's prospective payment system (PPS) transition and posttransition phases. Results suggest that the hospitals implemented distinct strategies in response to PPS. The posttransition strategies were examined for their association with improved revenue and utilization indicators. Few of the service diversification and promotional strategies were consistent predictors of performance. Emphasis on fine-tuning inpatient services was the most promising predictor of higher utilization and revenue measures. The implications for other rural hospitals are discussed.

  11. Responses to prospective payment by rural New Mexico hospitals.

    PubMed Central

    Smith, H L; Piland, N F; Phillipp, A M

    1991-01-01

    A cross-sectional study is used to determine how rural New Mexico hospitals altered service diversification, inpatient service emphasis, and service promotion during Medicare's prospective payment system (PPS) transition and posttransition phases. Results suggest that the hospitals implemented distinct strategies in response to PPS. The posttransition strategies were examined for their association with improved revenue and utilization indicators. Few of the service diversification and promotional strategies were consistent predictors of performance. Emphasis on fine-tuning inpatient services was the most promising predictor of higher utilization and revenue measures. The implications for other rural hospitals are discussed. PMID:1743969

  12. A Metal Bump Bonding Method Using Ag Nanoparticles as Intermediate Layer

    NASA Astrophysics Data System (ADS)

    Fu, Weixin; Nimura, Masatsugu; Kasahara, Takashi; Mimatsu, Hayata; Okada, Akiko; Shoji, Shuichi; Ishizuka, Shugo; Mizuno, Jun

    2015-11-01

    The future development of low-temperature and low-pressure bonding technology is necessary for fine-pitch bump application. We propose a bump structure using Ag nanoparticles as an intermediate layer coated on a fine-pitch Cu pillar bump. The intermediate layer is prepared using an efficient and cost-saving squeegee-coating method followed by a 100°C baking process. This bump structure can be easily flattened before the bonding process, and the low-temperature sinterability of the nanoparticles is retained. The bonding experiment was successfully performed at 250°C and 39.8 MPa and the bonding strength was comparable to that achieved via other bonding technology utilizing metal particles or porous material as bump materials.

  13. Size-dependent characteristics of ultra-fine oxygen-enriched nanoparticles in austenitic steels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miao, Yinbin; Mo, Kun; Zhou, Zhangjian

    2016-11-01

    Here, a coordinated investigation of the elemental composition and morphology of ultra-fine-scale nanoparticles as a function of size within a variety of austenitic oxide dispersion-strengthened (ODS) steels is reported. Atom probe tomography was utilized to evaluate the elemental composition of these nanoparticles. Meanwhile, the crystal structures and orientation relationships were determined by high resolution transmission electron microscopy. The nanoparticles with sufficient size (>4 nm) to maintain a Y2Ti2-xO7-2x stoichiometry were found to have a pyrochlore structure, whereas smaller YxTiyOz nanoparticles lacked a well-defined structure. The size-dependent characteristics of the nanoparticles in austenitic ODS steels differ from those in ferritic/martensitic ODSmore » steels.« less

  14. Remote sensing, geographical information systems, and spatial modeling for analyzing public transit services

    NASA Astrophysics Data System (ADS)

    Wu, Changshan

    Public transit service is a promising transportation mode because of its potential to address urban sustainability. Current ridership of public transit, however, is very low in most urban regions, particularly those in the United States. This woeful transit ridership can be attributed to many factors, among which poor service quality is key. Given this, there is a need for transit planning and analysis to improve service quality. Traditionally, spatially aggregate data are utilized in transit analysis and planning. Examples include data associated with the census, zip codes, states, etc. Few studies, however, address the influences of spatially aggregate data on transit planning results. In this research, previous studies in transit planning that use spatially aggregate data are reviewed. Next, problems associated with the utilization of aggregate data, the so-called modifiable areal unit problem (MAUP), are detailed and the need for fine resolution data to support public transit planning is argued. Fine resolution data is generated using intelligent interpolation techniques with the help of remote sensing imagery. In particular, impervious surface fraction, an important socio-economic indicator, is estimated through a fully constrained linear spectral mixture model using Landsat Enhanced Thematic Mapper Plus (ETM+) data within the metropolitan area of Columbus, Ohio in the United States. Four endmembers, low albedo, high albedo, vegetation, and soil are selected to model heterogeneous urban land cover. Impervious surface fraction is estimated by analyzing low and high albedo endmembers. With the derived impervious surface fraction, three spatial interpolation methods, spatial regression, dasymetric mapping, and cokriging, are developed to interpolate detailed population density. Results suggest that cokriging applied to impervious surface is a better alternative for estimating fine resolution population density. With the derived fine resolution data, a multiple route maximal covering/shortest path (MRMCSP) model is proposed to address the tradeoff between public transit service quality and access coverage in an established bus-based transit system. Results show that it is possible to improve current transit service quality by eliminating redundant or underutilized service stops. This research illustrates that fine resolution data can be efficiently generated to support urban planning, management and analysis. Further, this detailed data may necessitate the development of new spatial optimization models for use in analysis.

  15. Benthic oxygen consumption on continental shelves off eastern Canada

    NASA Astrophysics Data System (ADS)

    Grant, Jonathan; Emerson, Craig W.; Hargrave, Barry T.; Shortle, Jeannette L.

    1991-08-01

    The consumption of phytoplankton production by the benthos is an important component of organic carbon budgets for continental shelves. Sediment texture is a major factor regulating benthic processes because fine sediment areas are sites of enhanced deposition from the water column, resulting in increased organic content, bacterial biomass and community metabolism. Although continental shelves at mid- to high latitudes consist primarily of coarse relict sediments ( PIPER, Continental Shelf Research, 11, 1013-1035), shelf regions of boreal and subarctic eastern Canada contain large areas of silt and clay sediments ( FADER, Continental Shelf Research, 11, 1123-1153). We collated estimates of benthic oxygen consumption in coarse (<20% silt-clay, <0.5% organic matter) and fine sediments (20% silt-clay, 0.5% organic matter) for northwest Atlantic continental shelves including new data for Georges Bank, the Scotian Shelf, the Grand Banks of Newfoundland and Labrador Shelf. Estimates were applied to the areal distribution of sediment type on these shelves to obtain a general relationship between sediment texture and benthic carbon consumption. Mean benthic oxygen demand was 2.7 times greater in fine sediment than in coarse sediment, when normalized to mean annual temperature. In terms of carbon equivalents, shelf regions with minimal fine sediment (Georges Bank, the Grand Banks of Newfoundland-northeast Newfoundland) consumed only 5-8% of annual primary production. Benthos of the Gulf of Maine (100% fine sediment) and the Scotian Shelf (35% fine sediment) utilized 16-19% of primary production. Although 32% of the Labrador Shelf area contained fine sediments, benthic consumption of pelagic production (8%) was apparently limited by low mean annual temperature (2°C). These results indicate that incorporation of sediment-specific oxygen uptake into shelf carbon budgets may increase estimates of benthic consumption by 50%. Furthermore, respiration and production by large macrofauna allow an even greater proportion of primary production to enter benthic pathways. Fine sediment areas (shelf basins or "depocenters") are postulated to be sites of enhanced biological activity which must be considered in the modelling of shelf carbon budgets and the role of the benthos in demersal fisheries.

  16. Investigation of Nonlinear Site Response and Seismic Compression from Case History Analysis and Laboratory Testing

    NASA Astrophysics Data System (ADS)

    Yee, Eric

    In this thesis I address a series of issues related to ground failure and ground motions during earthquakes. A major component is the evaluation of cyclic volumetric strain behavior of unsaturated soils, more commonly known as seismic compression, from advanced laboratory testing. Another major component is the application of nonlinear and equivalent linear ground response analyses to large-strain problems involving highly nonlinear dynamic soil behavior. These two components are merged in the analysis of a truly unique and crucial field case history of nonlinear site response and seismic compression. My first topic concerns dynamic soil testing for relatively small strain dynamic soil properties such as threshold strains, gammatv. Such testing is often conducted using specialized devices such as dual-specimen simple-shear, as devices configured for large strain testing produce noisy signals in the small strain range. Working with a simple shear device originally developed for large-strain testing, I extend its low-strain capabilities by characterizing noisy signals and utilizing several statistical methods to extract meaningful responses in the small strain range. I utilize linear regression of a transformed variable to estimate the cyclic shear strain from a noisy signal and the confidence interval on its amplitude. I utilize Kernel regression with the Nadaraya-Watson estimator and a Gaussian kernel to evaluate vertical strain response. A practical utilization of these techniques is illustrated by evaluating threshold shear strains for volume change with a procedure that takes into account uncertainties in the measured shear and vertical strains. My second topic concerns the seismic compression characteristics of non-plastic and low-plasticity silty sands with varying fines content (10 ≤ FC ≤ 60%). Simple shear testing was performed on various sand-fines mixtures at a range of modified Proctor relative compaction levels ( RC) and degrees-of-saturation (S). Aside from the expected strong influence of RC, increasing fines content is found to generally decrease volume change for fines fractions consisting of silts and clayey silts with moderate to low plasticity. With truly non-plastic fines (rock flour), cyclic volume change increases with FC. Some materials also exhibit an effect of as-compacted saturation in which moderate saturation levels associated with high matric suction cause volume change to decrease. A preliminary empirical model to capture these effects is presented. The balance of the dissertation is related to a case history of strongly nonlinear site response and seismic compression associated with a free-field downhole array installed near the Service Hall at the Kashiwazaki-Kariwa nuclear power plant, which recorded strong ground motions from the Mw 6.6 2007 Niigata-ken Chuetsu-oki earthquake. Site conditions at the array consist of about 70 m of medium-dense sands overlying clayey bedrock, with ground water located at 45 m. Ground shaking at the bedrock level had geometric mean peak accelerations of 0.55 g which is reduced to 0.4 g at the ground surface, indicating nonlinear site response. Ground settlements of approximately 15+/-5 cm occurred at the site. A site investigation was performed to develop relevant soil properties for ground response and seismic compression analysis, including shear wave velocities, shear strength, relative density, and modulus reduction and damping curves. (Abstract shortened by UMI.)

  17. Fine mapping and candidate gene analysis of the dominant glandless gene Gl^e2 in cotton (Gossypium spp.)

    USDA-ARS?s Scientific Manuscript database

    Cottonseed product is an excellent source of oil and protein. However, this nutrition source is greatly limited in utilization by the toxic gossypol in pigment glands. It is reported that the Gl2e gene could effectively control the formation of the pigment glands. Here, three F2 populations were c...

  18. Utilizing Community Resources To Enhance Creativeness and Aesthetic Awareness in Head Start Teachers.

    ERIC Educational Resources Information Center

    Irving, Virginia

    The primary goal of this practicum study was to provide opportunities for Head Start teachers to become knowledgeable of community resources that would encourage their aesthetic awareness and enhance their creative growth. A total of 16 teachers and teacher aides visited a local Dali Museum, a fine arts museum, a planetarium, a historical museum,…

  19. NREL Helps Utilities Develop Next Generation Plug-in Hybrid Electric Trucks

    Science.gov Websites

    operation, and fine-tune the design of such vehicles before expanding their use in the PG&E or other Vehicle Performance Data Based on Real-World Operation "NREL has been working with PG&E to accessories function in real-world operation." To date, NREL has captured and is currently analyzing four

  20. Customization of Protein Single Nanowires for Optical Biosensing.

    PubMed

    Sun, Yun-Lu; Sun, Si-Ming; Wang, Pan; Dong, Wen-Fei; Zhang, Lei; Xu, Bin-Bin; Chen, Qi-Dai; Tong, Li-Min; Sun, Hong-Bo

    2015-06-24

    An all-protein single-nanowire optical biosensor is constructed by a facile and general femtosecond laser direct writing approach with nanoscale structural customization. As-formed protein single nanowires show excellent optical properties (fine waveguiding performance and bio-applicable transmission windows), and are utilized as evanescent optical nanobiosensors for label-free biotin detection. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. A High-Linearity, Ring-Oscillator-Based, Vernier Time-to-Digital Converter Utilizing Carry Chains in FPGAs

    NASA Astrophysics Data System (ADS)

    Cui, Ke; Ren, Zhongjie; Li, Xiangyu; Liu, Zongkai; Zhu, Rihong

    2017-01-01

    Time-to-digital converters (TDCs) using dedicated carry chains of field programmable gate arrays (FPGAs) are usually organized in tapped-delay-line type which are intensively researched in recent years. However this method incurs poor differential nonlinearity (DNL) which arises from the inherent uneven bin granularity. This paper proposes a TDC architecture which utilizes the carry chains in a quite different manner in order to alleviate this long-standing problem. Two independent carry chains working as the delay lines for the fine time interpolation are organized in a ring-oscillator-based Vernier style and the time difference between them is finely adjusted by assigning different number of basic delay cells. A specific design flow is described to obtain the desired delay difference. The TDC was implemented on a Stratix III FPGA. Test results show that the obtained resolution is 31 ps and the DNL\\INL is in the range of (-0.080 LSB, 0.073 LSB)(-0.087 LSB, 0.091 LSB). This demonstrates that the proposed architecture greatly improves linearity compared to previous techniques. Additionally the resource cost is rather low which uses only 319 LUTs and 104 registers per TDC channel.

  2. The Dynamics of Fine Mode Aerosol Optical Properties in South Korea from AERONET and Aircraft Observations with a Focus on Cases with Large Cloud Fraction and/or Fog During KORUS-AQ

    NASA Astrophysics Data System (ADS)

    Eck, T. F.; Holben, B. N.; Kim, J.; Choi, M.; Giles, D. M.; Schafer, J.; Smirnov, A.; Slutsker, I.; Sinyuk, A.; Sorokin, M. G.; Kraft, J.; Beyersdorf, A. J.; Anderson, B. E.; Thornhill, K. L., II; Crawford, J. H.

    2017-12-01

    The focus of our investigation is of major fine mode aerosol pollution events in South Korea, particularly when cloud fraction is high. This work includes the analysis of AERONET data utilizing the Spectral Deconvolution Algorithm to enable detection of fine mode aerosol optical depth (AOD) near to clouds. Additionally we analyze the newly developed AERONET V3 data sets that have significant changes to cloud screening algorithms. Comparisons of aerosol optical depth are made between AERONET Versions 2 and 3 for both long-term climatology data and for specific 2016 cases, especially in May and June 2016 during the KORUS-AQ field campaign. In general the Version 3 cloud screening allows many more fine mode AOD observations to reach Level 2 when cloud amount is high, as compared to Version 2, thereby enabling more thorough analysis of these types of cases. Particular case studies include May 25-26, 2016 when cloud fraction was very high over much of the peninsula, associated with a frontal passage and advection of pollution from China. Another interesting case is June 9, 2016 when there was fog over the West Sea, and this seems to have affected aerosol properties well downwind over the Korean peninsula. Both of these days had KORUS-AQ research aircraft flights that provided observations of aerosol absorption, particle size distributions and vertical profiles of extinction. AERONET retrievals and aircraft in situ measurements both showed high single scattering albedo (weak absorption) on these cloudy days. We also investigate the relationship between aerosol fine mode radius and AOD and the relationship between aerosol single scattering albedo and fine mode particle radius from the AERONET almucantar retrievals for the interval of April through June 2016 for 17 AERONET sites in South Korea. Strongly increasing fine mode radius (leading to greater scattering efficiency) as fine mode AOD increased is one factor contributing to a trend of increasing single scattering albedo as fine AOD increased. Additionally, the new AERONET Hybrid sky radiance scan retrievals that allow for inversions to be made at much smaller solar zenith angles are analyzed and compared to almucantar retrievals.

  3. Low-temperature adsorption of H2S on Ni(001) studied by near-edge- and surface-extended-x-ray-absorption fine structure

    NASA Astrophysics Data System (ADS)

    McGrath, R.; MacDowell, A. A.; Hashizume, T.; Sette, F.; Citrin, P. H.

    1989-11-01

    The adsorption of H2S on Ni(001) has been studied with surface-extended x-ray-absorption fine structure and near-edge x-ray-absorption fine structure (NEXAFS) using the AT&T Bell Laboratories X15B beamline at the National Synchrotron Light Source. At 95 K and full saturation coverage, ~0.45 monolayer (ML) of S atoms in fourfold-hollow sites are produced, characteristic of room-temperature adsorption, accompanied by ~0.05 ML of oriented molecular H2S. Both these atomic and molecular chemisorbed species are buried under ~0.9 ML of disordered physisorbed H2S. No evidence for HS is found. Above 190 K the two molecular H2S phases desorb, leaving only dissociated S. These findings differ from previously reported interpretations of data obtained with high-resolution electron-energy-loss spectroscopy. They also exemplify the utility of NEXAFS for identifying and quantifying atomic and molecular surface species even when their difference involves only H and the two species coexist.

  4. Papular skin lesions: Clue to a recurrence of breast cancer on fine needle non-aspiration cytology (FNNAC)

    PubMed Central

    Afrose, Ruquiya; Akram, Mohammad; Siddiqui, Shahid Ali

    2015-01-01

    Cutaneous metastasis from underlying carcinoma is relatively uncommon in clinical practice. A high index of suspicion is required to diagnose these lesions, as these lesions can mimic benign skin lesions and clinical findings may be subtle. Fine needle aspiration cytology (FNAC) is commonly employed for diagnosing these skin lesions. However, it is often difficult to aspirate adequate material from small papular lesions. In these clinical situations, fine needle non-aspiration cytology (FNNAC) is proposed as an alternative procedure. FNNAC eliminates the negative suction pressure employed in FNAC and decreases the dilution of tumor cells by blood and hence yields adequate diagnostic material. We report here a case in which FNNAC was used in place of FNAC in diagnosing papular skin lesions. This procedure was carried out in a treated patient of carcinoma breast who was on regular follow-up and presented to us with a 20-day history of papular skin lesions over the chest and back. This article enlightens the clinicians about the utility of FNNAC, which is a relatively uncommon procedure. PMID:25948954

  5. Papular skin lesions: Clue to a recurrence of breast cancer on fine needle non-aspiration cytology (FNNAC).

    PubMed

    Afrose, Ruquiya; Akram, Mohammad; Siddiqui, Shahid Ali

    2015-01-01

    Cutaneous metastasis from underlying carcinoma is relatively uncommon in clinical practice. A high index of suspicion is required to diagnose these lesions, as these lesions can mimic benign skin lesions and clinical findings may be subtle. Fine needle aspiration cytology (FNAC) is commonly employed for diagnosing these skin lesions. However, it is often difficult to aspirate adequate material from small papular lesions. In these clinical situations, fine needle non-aspiration cytology (FNNAC) is proposed as an alternative procedure. FNNAC eliminates the negative suction pressure employed in FNAC and decreases the dilution of tumor cells by blood and hence yields adequate diagnostic material. We report here a case in which FNNAC was used in place of FNAC in diagnosing papular skin lesions. This procedure was carried out in a treated patient of carcinoma breast who was on regular follow-up and presented to us with a 20-day history of papular skin lesions over the chest and back. This article enlightens the clinicians about the utility of FNNAC, which is a relatively uncommon procedure.

  6. Pulsed high energy synthesis of fine metal powders

    NASA Technical Reports Server (NTRS)

    Witherspoon, F. Douglas (Inventor); Massey, Dennis W. (Inventor)

    1999-01-01

    Repetitively pulsed plasma jets generated by a capillary arc discharge at high stagnation pressure (>15,000 psi) and high temperature (>10,000 K) are utilized to produce 0.1-10 .mu.m sized metal powders and decrease cost of production. The plasma jets impact and atomize melt materials to form the fine powders. The melt can originate from a conventional melt stream or from a pulsed arc between two electrodes. Gas streams used in conventional gas atomization are replaced with much higher momentum flux plasma jets. Delivering strong incident shocks aids in primary disintegration of the molten material. A series of short duration, high pressure plasma pulses fragment the molten material. The pulses introduce sharp velocity gradients in the molten material which disintegrates into fine particles. The plasma pulses have peak pressures of approximately one kilobar. The high pressures improve the efficiency of disintegration. High gas flow velocities and pressures are achieved without reduction in gas density. Repetitively pulsed plasma jets will produce powders with lower mean size and narrower size distribution than conventional atomization techniques.

  7. The international fine aerosol networks

    NASA Astrophysics Data System (ADS)

    Cahill, Thomas A.

    1993-04-01

    The adoption by the United States of a PIXE-based protocol for its fine aerosol network, after open competitions involving numerous laboratories and methods, has encouraged cooperation with other countries possessing similar capabilities and similar needs. These informal cooperative programs, involving about a dozen countries at the end of 1991, almost all use PIXE as a major component of the analytical protocols. The University of California, Davis, Air Quality Group assisted such programs through indefinite loans of a quality assurance sampler, the IMPROVE Channel A, and analyses at no cost of a small fraction of the samples taken in a side-by-side configuration. In December 1991, the World Meteorological Organization chose a protocol essentially identical to IMPROVE for the Global Atmospheric Watch (GAW) network and began deploying units, the IMPROVE Channel A, to sites around the world. Preferred analyses include fine (less than about 2.5 μm) mass, ions by ion chromatography and elements by PIXE + PESA (or, lacking that, XRF). This paper will describe progress in both programs, giving examples of the utility of the data and projecting the future expansion of the network to about 20 GAW sites by 1994.

  8. Design and evaluation of an optical fine-pointing control system for telescopes utilizing a digital star sensor

    NASA Technical Reports Server (NTRS)

    Ostroff, A. J.; Romanczyk, K. C.

    1973-01-01

    One of the most significant problems associated with the development of large orbiting astronomical telescopes is that of maintaining the very precise pointing accuracy required. A proposed solution to this problem utilizes dual-level pointing control. The primary control system maintains the telescope structure attitude stabilized within the field of view to the desired accuracy. In order to demonstrate the feasibility of optically stabilizing the star images to the desired accuracy a regulating system has been designed and evaluated. The control system utilizes a digital star sensor and an optical star image motion compensator, both of which have been developed for this application. These components have been analyzed mathematically, analytical models have been developed, and hardware has been built and tested.

  9. Influence of diet pellet hardness and particle size on food utilization by mice, rats and hamsters.

    PubMed

    Ford, D J

    1977-10-01

    Increasing hardness of diet pellets reduced food wastage by each species. Also, less wastage occurred when pellets made from finely ground materials were given, an effect that was not related to hardness. The hardest diet reduced growth of the mice by reducing true food consumption and a poorer food conversion efficiency (true food consumption/growth) was obtained. Apparent food consumption increased with the softness of the diet and food utilization (apparent food consumption/growth) of the softest diets was less efficient than those of the others. Grinding of the raw materials prior to pelleting had no effect on food conversion, but food utilization was less efficient because of the greater wastage of pellets from coarsely ground materials and consequent apparent food comsumption.

  10. Shape memory alloy/shape memory polymer tools

    DOEpatents

    Seward, Kirk P.; Krulevitch, Peter A.

    2005-03-29

    Micro-electromechanical tools for minimally invasive techniques including microsurgery. These tools utilize composite shape memory alloy (SMA), shape memory polymer (SMP) and combinations of SMA and SMP to produce catheter distal tips, actuators, etc., which are bistable. Applications for these structures include: 1) a method for reversible fine positioning of a catheter tip, 2) a method for reversible fine positioning of tools or therapeutic catheters by a guide catheter, 3) a method for bending articulation through the body's vasculature, 4) methods for controlled stent delivery, deployment, and repositioning, and 5) catheters with variable modulus, with vibration mode, with inchworm capability, and with articulated tips. These actuators and catheter tips are bistable and are opportune for in vivo usage because the materials are biocompatible and convenient for intravascular use as well as other minimal by invasive techniques.

  11. Time and space integrating acousto-optic folded spectrum processing for SETI

    NASA Technical Reports Server (NTRS)

    Wagner, K.; Psaltis, D.

    1986-01-01

    Time and space integrating folded spectrum techniques utilizing acousto-optic devices (AOD) as 1-D input transducers are investigated for a potential application as wideband, high resolution, large processing gain spectrum analyzers in the search for extra-terrestrial intelligence (SETI) program. The space integrating Fourier transform performed by a lens channels the coarse spectral components diffracted from an AOD onto an array of time integrating narrowband fine resolution spectrum analyzers. The pulsing action of a laser diode samples the interferometrically detected output, aliasing the fine resolution components to baseband, as required for the subsequent charge coupled devices (CCD) processing. The raster scan mechanism incorporated into the readout of the CCD detector array is used to unfold the 2-D transform, reproducing the desired high resolution Fourier transform of the input signal.

  12. Ear Scaffold Reconstruction Using Ultrasonic Aspirator for Cauliflower Ear.

    PubMed

    Hao, Scarlett; Angster, Kristen; Hubbard, Fleesie; Greywoode, Jewel; Vakharia, Kalpesh T

    2018-04-01

    Untreated auricular hematomas from ear trauma can result in an ear deformation known as cauliflower ear, secondary to fibrosis and new cartilage overgrowth. Cauliflower ear reconstruction has traditionally utilized tools such as a drill or a scalpel in order to improve auricular cosmesis. We present a case report utilizing an ultrasonic aspirator to recontour the fibrosed cartilage of a cauliflower ear. The ultrasonic aspirator has advantages over traditional tools in its ability to provide finely controlled bone removal without damage to surrounding soft tissue. The patient in this case report underwent multistage reconstruction using the ultrasonic aspirator with excellent cosmetic result and patient satisfaction.

  13. A study on the performance of concrete containing recycled aggregates and ceramic as materials replacement

    NASA Astrophysics Data System (ADS)

    Azmi, N. B.; Khalid, F. S.; Irwan, J. M.; Anting, N.; Mazenan, P. N.

    2017-11-01

    Natural fine aggregate materials are commonly used in development and commercial construction in Malaysia. In fact, concrete production was increased as linear with the growing Malaysia economy. However, an issue was production of concrete was to locate adequate sources of natural fine aggregates. There lot of studies have been conducted in order to replace the fine aggregate in which natural fine aggregate replace with the waste material in concrete preparation. Therefore, this study aims to utilize the Recycled Concrete Aggregate (RCA) and ceramic waste which has great potential to replace the natural aggregate in concrete mix with different type of method, admixture, and parameters. This research were focused on compressive strength and water absorption test to determine the optimum mix ratio of concrete mix. The concrete aggregate was chosen due to improvement capillary bonding mechanisms and ceramic presented similar strength compared to the conventional concrete using natural aggregate. Percent of replacement have been used in this study was at 25%, 35% and 45% of the RCA and 5%, 10% and 15% for ceramic, respectively. Furthermore, this research was conduct to find the optimum percentage of aggregate replacement, using water-cement ratio of 0.55 with concrete grade 25/30. The best percentage of replacement was the RCA35% C15% with the compressive strength of 34.72 MPa and the water absorption was satisfied.

  14. Studies on the reduction kinetics of hematite iron ore pellets with noncoking coals for sponge iron plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kumar, M.; Mohapatra, P.; Patel, S.K.

    2009-07-01

    In the present investigation, fired pellets were made by mixing hematite iron ore fines of -100, -16+18, and -8+10 mesh size in different ratios and studies on their reduction kinetics in Lakhanpur, Orient OC-2 and Belpahar coals were carried out at temperatures ranging from 850{sup o}C to 1000{sup o}C with a view toward promoting the massive utilization of fines in ironmaking. The rate of reduction in all the fired iron ore pellets increased markedly with an increase in temperature up to 1000{sup o}C, and it was more intense in the first 30min. The values of activation energy, calculated from integralmore » and differential approaches, for the reduction of fired pellets (prepared from iron ore fines of -100 mesh size) in coals were found to be in the range 131-148 and 130-181 kJ mol{sup -1} (for =0.2 to 0.8), indicating the process is controlled by a carbon gasification reaction. The addition of selected larger size particles in the matrix of -100 mesh size fines up to the extent studied decreased the activation energy and slightly increased the reduction rates of resultant fired pellets. In comparison to coal, the reduction of fired pellets in char was characterized by significantly lower reduction rates and higher activation energy.« less

  15. Observing Mode Attitude Controller for the Lunar Reconnaissance Orbiter

    NASA Technical Reports Server (NTRS)

    Calhourn, Philip C.; Garrick, Joseph C.

    2007-01-01

    The Lunar Reconnaissance Orbiter (LRO) mission is the first of a series of lunar robotic spacecraft scheduled for launch in Fall 2008. LRO will spend at least one year in a low altitude polar orbit around the Moon, collecting lunar environment science and mapping data to enable future human exploration. The LRO employs a 3-axis stabilized attitude control system (ACS) whose primary control mode, the "Observing mode", provides Lunar Nadir, off-Nadir, and Inertial fine pointing for the science data collection and instrument calibration. The controller combines the capability of fine pointing with that of on-demand large angle full-sky attitude reorientation into a single ACS mode, providing simplicity of spacecraft operation as well as maximum flexibility for science data collection. A conventional suite of ACS components is employed in this mode to meet the pointing and control objectives. This paper describes the design and analysis of the primary LRO fine pointing and attitude re-orientation controller function, known as the "Observing mode" of the ACS subsystem. The control design utilizes quaternion feedback, augmented with a unique algorithm that ensures accurate Nadir tracking during large angle yaw maneuvers in the presence of high system momentum and/or maneuver rates. Results of system stability analysis and Monte Carlo simulations demonstrate that the observing mode controller can meet fine pointing and maneuver performance requirements.

  16. Use of wastes derived from earthquakes for the production of concrete masonry partition wall blocks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiao Zhao; Faculty of Architecture, Civil Engineering and Environment Engineering and Mechanics, Sichuan University; Ling, Tung-Chai

    2011-08-15

    Highlights: > Solved the scientific and technological challenges impeding use of waste rubble derived from earthquake, by providing an alternative solution of recycling the waste in moulded concrete block products. > Significant requirements for optimum integration on the utilization of the waste aggregates in the production of concrete blocks are investigated. > A thorough understanding of the mechanical properties of concrete blocks made with waste derived from earthquake is reported. - Abstract: Utilization of construction and demolition (C and D) wastes as recycled aggregates in the production of concrete and concrete products have attracted much attention in recent years. However,more » the presence of large quantities of crushed clay brick in some the C and D waste streams (e.g. waste derived collapsed masonry buildings after an earthquake) renders the recycled aggregates unsuitable for high grade use. One possibility is to make use of the low grade recycled aggregates for concrete block production. In this paper, we report the results of a comprehensive study to assess the feasibility of using crushed clay brick as coarse and fine aggregates in concrete masonry block production. The effects of the content of crushed coarse and fine clay brick aggregates (CBA) on the mechanical properties of non-structural concrete block were quantified. From the experimental test results, it was observed that incorporating the crushed clay brick aggregates had a significant influence on the properties of blocks. The hardened density and drying shrinkage of the block specimens decreased with an increase in CBA content. The use of CBA increased the water absorption of block specimens. The results suggested that the amount of crushed clay brick to be used in concrete masonry blocks should be controlled at less than 25% (coarse aggregate) and within 50-75% for fine aggregates.« less

  17. Ash particulate formation from pulverized coal under oxy-fuel combustion conditions.

    PubMed

    Jia, Yunlu; Lighty, JoAnn S

    2012-05-01

    Aerosol particulates are generated by coal combustion. The amount and properties of aerosol particulates, specifically size distribution and composition, can be affected by combustion conditions. Understanding the formation of these particles is important for predicting emissions and understanding potential deposition. Oxy-fuel combustion conditions utilize an oxygen-enriched gas environment with CO(2). The high concentration of CO(2) is a result of recycle flue gas which is used to maintain temperature. A hypothesis is that high CO(2) concentration reduces the vaporization of refractory oxides from combustion. A high-temperature drop-tube furnace was used under different oxygen concentrations and CO(2) versus N(2) to study the effects of furnace temperature, coal type, and gas phase conditions on particulate formation. A scanning mobility particle sizer (SMPS) and aerodynamic particle sizer (APS) were utilized for particle size distributions ranging from 14.3 nm to 20 μm. In addition, particles were collected on a Berner low pressure impactor (BLPI) for elemental analysis using scanning electron microscopy and energy dispersive spectroscopy. Three particle size modes were seen: ultrafine (below 0.1 μm), fine (0.1 to 1.0 μm), and coarse (above 1 μm). Ultrafine mass concentrations were directly related to estimated particle temperature, increasing with increasing temperature. For high silicon and calcium coals, Utah Skyline and PRB, there was a secondary effect due to CO(2) and the hypothesized reaction. Illinois #6, a high sulfur coal, had the highest amount of ultrafine mass and most of the sulfur was concentrated in the ultrafine and fine modes. Fine and coarse mode mass concentrations did not show a temperature or CO(2) relationship. (The table of contents graphic and abstract graphic are adapted from ref 27.). © 2012 American Chemical Society

  18. A large-scale forest landscape model incorporating multi-scale processes and utilizing forest inventory data

    Treesearch

    Wen J. Wang; Hong S. He; Martin A. Spetich; Stephen R. Shifley; Frank R. Thompson III; David R. Larsen; Jacob S. Fraser; Jian Yang

    2013-01-01

    Two challenges confronting forest landscape models (FLMs) are how to simulate fine, standscale processes while making large-scale (i.e., .107 ha) simulation possible, and how to take advantage of extensive forest inventory data such as U.S. Forest Inventory and Analysis (FIA) data to initialize and constrain model parameters. We present the LANDIS PRO model that...

  19. An Integrated Look at Middle School Engagement and Learning in Digital Environments as Precursors to College Attendance

    ERIC Educational Resources Information Center

    San Pedro, Maria Ofelia Z.; Baker, Ryan S.; Heffernan, Neil T.

    2017-01-01

    Middle school is an important phase in the academic trajectory, which plays a major role in the path to successful post-secondary outcomes such as going to college. Despite this, research on factors leading to college-going choices do not yet utilize the extensive fine-grained data now becoming available on middle school learning and engagement.…

  20. Study of effective utilization of iron ore sinter through arc plasma

    NASA Astrophysics Data System (ADS)

    Swain, Biswajit; Samal, S. K.; Mohanty, M. K.; Behera, A.; Mishra, S. C.

    2018-03-01

    Generation of fines is common in mining, sizing, and beneficiation and also in high-temperature metallurgical processes as the disintegration of agglomerate/compact occurs. Extraction of metallic iron from ore fines is one of the challenging aspects of iron making industries as the liberation of fines blocks, the charge burden porosity and hence hinders the reduction rate. Along with size factor, mineral composition plays a vital role in the extraction process; particularly silica. As silica has the very high tendency towards iron oxide, at comparatively low temperature, the activity of silica should be suppressed to prevent silicate phases. Adjustment of such conditions is controlled by addition of lime, but sometimes excessive slag generation increases the cost of production. In the present work, carbothermic reduction of partially reduced iron bearing pellets has been melted through 20 KW DC arc plasma furnace, and a comparative study has been made for considering different slag chemistry approaches. Pellets as aforementioned are made available from Patnaik Steel and Alloys Ltd, Odisha, having high silica content ore fines (of about 8.6%) as obtained from the chemical analysis. X-Ray analysis and optical image analyzer result of sinter thus obtained reveal that fayalite phase has major fractional value. Smelting works were done for sinter with/without adjustment of slag chemistry, where argon and nitrogen were used as plasma forming gases. A range of recovery rates (between 87-94%) is achieved by charge composition, ionizing gases, and smelting duration. It is observed that use of nitrogen as plasma forming gas increases the recovery rate than that of using only argon plasma; due to high energy flux of nitrogen which increases the enthalpy due to its diatomicity. A maximum recovery rate of about 94% is achieved for process duration of 13minutes utilizing nitrogen plasma. Smelting of charge with the addition of hydrated lime targeting melilite as final slag resulted in the formation of metallic iron as confirmed from XRD and XRF analyses. In the other hand, ferrosilicon is liberated in the metallic parts where smelting of charge was done without adjustment of slag chemistry. Both metal and slag thus obtained are characterized by XRD, XRF, microhardness and wet chemical analysis suitably.

  1. Using dynamic Brownian bridge movement modelling to measure temporal patterns of habitat selection.

    PubMed

    Byrne, Michael E; Clint McCoy, J; Hinton, Joseph W; Chamberlain, Michael J; Collier, Bret A

    2014-09-01

    Accurately describing animal space use is vital to understanding how wildlife use habitat. Improvements in GPS technology continue to facilitate collection of telemetry data at high spatial and temporal resolutions. Application of the recently introduced dynamic Brownian bridge movement model (dBBMM) to such data is promising as the method explicitly incorporates the behavioural heterogeneity of a movement path into the estimated utilization distribution (UD). Utilization distributions defining space use are normally estimated for time-scales ranging from weeks to months, obscuring much of the fine-scale information available from high-volume GPS data sets. By accounting for movement heterogeneity, the dBBMM provides a rigorous, behaviourally based estimate of space use between each set of relocations. Focusing on UDs generated between individual sets of locations allows us to quantify fine-scale circadian variation in habitat use. We used the dBBMM to estimate UDs bounding individual time steps for three terrestrial species with different life histories to illustrate how the method can be used to identify fine-scale variations in habitat use. We also demonstrate how dBBMMs can be used to characterize circadian patterns of habitat selection and link fine-scale patterns of habitat use to behaviour. We observed circadian patterns of habitat use that varied seasonally for a white-tailed deer (Odocoileus virginianus) and coyote (Canis latrans). We found seasonal patterns in selection by the white-tailed deer and were able to link use of conifer forests and agricultural fields to behavioural state of the coyote. Additionally, we were able to quantify the date in which a Rio Grande wild turkey (Meleagris gallopavo intermedia) initiated laying as well as when during the day, she was most likely to visit the nest site to deposit eggs. The ability to quantify circadian patterns of habitat use may have important implications for research and management of wildlife. Additionally, the ability to link such patterns to behaviour may aid in the development of mechanistic models of habitat selection. © 2014 The Authors. Journal of Animal Ecology © 2014 British Ecological Society.

  2. Elucidating the impacts of initial supersaturation and seed crystal loading on struvite precipitation kinetics, fines production, and crystal growth.

    PubMed

    Agrawal, Shantanu; Guest, Jeremy S; Cusick, Roland D

    2018-04-01

    To reduce intra-plant nutrient cycling, and recover phosphorus (P) fertilizers from nutrient-rich sidestreams, wastewater utilities increasingly elect to employ struvite precipitation processes without a clear understanding of the inherent tradeoffs associated with specific design and operating decisions. Specifically, the impact of reactor conditions on struvite crystallization rate, and distribution between formation of fines particles and secondary growth onto large diameter seed crystals represent critical knowledge gaps limiting the predictive capabilities of existing process models. In this work, the relative impacts of initial supersaturation (S i ), and seed loading, on P removal kinetics, and struvite solids distribution were investigated. In experiments conducted at different levels of initial supersaturation (1.7-2.4) and seed loading (0-25 g L -1 ), struvite fines represented the majority of phosphate solids formed in 10 of 12 conditions. While total P removal was dependent on S i , and primarily attributed to formation of fines, the concentration of struvite seed granules had a significant impact on the rate of P removal. Struvite seed granules increased the rate of precipitation by reducing induction time of primary nucleation of struvite fines. Secondary crystal growth represented the majority of struvite solids formed at high seed loading and low S i , but presented the tradeoff of low total removal and low rate of removal. To convey the significance of these findings on process modeling, we show how a prominent kinetic model with a first-order dependency on solid struvite concentration over-predicts P removal rate when total mass is dominated by large diameter seeds (0.9 mm). This works reveals the critical role of struvite fines in P removal, and highlights the need to account for their production and kinetic importance in struvite process design and operation. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. Characterization of Fine Airborne Particulate Collected in Tokyo and Major Atmospheric Emission Sources by Using Single Particle Measurement of SEM-EDX

    NASA Astrophysics Data System (ADS)

    Sato, K.; Iijima, A.; Furuta, N.

    2008-12-01

    In our long-term monitoring of size-classified Airborne Particulate Matter (APM) in Tokyo since 1995, it had been demonstrated that toxic elements such as As, Se, Cd, Sb and Pb were extremely enriched in fine APM (PM2.5). However, in that study, total sampled APM on a filter was digested with acids, and thus only averaged elemental composition in fine APM could be obtained. One of the effective methods to determine the origin of APM is single particle measurement by using SEM-EDX. By using characteristic shapes observed by SEM and marker elements contained in APM measured by EDX, detailed information for source identification can be obtained. In this study, fine APM (PM2.5) was collected at various locations such as roadside, diesel vehicle exhaust, a heavy oil combustion plant and a waste incineration plant as well as ambient atmosphere in Tokyo, and characteristics of fine particles that will be utilized for identification of emission sources are elucidated. Fine particles can be classified into 3 main characteristic shape groups; edge-shaped, cotton-like and spherical. Shape of particles collected in a heavy oil combustion plant and a waste incineration plant was mostly spherical, and these particles may be associated with thermal process. Diesel exhaust particles were predominantly cotton-like which may consist of coagulated nano-sized particles. Most of brake abrasion dusts were edge-shaped, which may be associated with mechanical abrasion of brake pads. In the elemental analysis of fine particles, high concentrations of Sb, Cu, Ti and Ba were detected in brake abrasion dusts. Since these elements are major constituents of brake pads, these can be used for marker elements of brake abrasion dusts. High concentration of C was detected in diesel exhaust particles and oil combustion particles, and thus C can be used for marker elements of their origin. Furthermore, high concentrations of C, Ca and K were detected in fly ash from a waste incineration plant, which may be associated with emission from biomass combustion.

  4. A simulation for gravity fine structure recovery from low-low GRAVSAT SST data

    NASA Technical Reports Server (NTRS)

    Estes, R. H.; Lancaster, E. R.

    1976-01-01

    Covariance error analysis techniques were applied to investigate estimation strategies for the low-low SST mission for accurate local recovery of gravitational fine structure, considering the aliasing effects of unsolved for parameters. A 5 degree by 5 degree surface density block representation of the high order geopotential was utilized with the drag-free low-low GRAVSAT configuration in a circular polar orbit at 250 km altitude. Recovery of local sets of density blocks from long data arcs was found not to be feasible due to strong aliasing effects. The error analysis for the recovery of local sets of density blocks using independent short data arcs demonstrated that the estimation strategy of simultaneously estimating a local set of blocks covered by data and two "buffer layers" of blocks not covered by data greatly reduced aliasing errors.

  5. Programmable Differential Delay Circuit With Fine Delay Adjustment

    DOEpatents

    DeRyckere, John F.; Jenkins, Philip Nord; Cornett, Frank Nolan

    2002-07-09

    Circuitry that provides additional delay to early arriving signals such that all data signals arrive at a receiving latch with same path delay. The delay of a forwarded clock reference is also controlled such that the capturing clock edge will be optimally positioned near quadrature (depending on latch setup/hold requirements). The circuitry continuously adapts to data and clock path delay changes and digital filtering of phase measurements reduce errors brought on by jittering data edges. The circuitry utilizes only the minimum amount of delay necessary to achieve objective thereby limiting any unintended jitter. Particularly, this programmable differential delay circuit with fine delay adjustment is designed to allow the skew between ASICS to be minimized. This includes skew between data bits, between data bits and clocks as well as minimizing the overall skew in a channel between ASICS.

  6. Three-Dimensional Viscous Alternating Direction Implicit Algorithm and Strategies for Shape Optimization

    NASA Technical Reports Server (NTRS)

    Pandya, Mohagna J.; Baysal, Oktay

    1997-01-01

    A gradient-based shape optimization based on quasi-analytical sensitivities has been extended for practical three-dimensional aerodynamic applications. The flow analysis has been rendered by a fully implicit, finite-volume formulation of the Euler and Thin-Layer Navier-Stokes (TLNS) equations. Initially, the viscous laminar flow analysis for a wing has been compared with an independent computational fluid dynamics (CFD) code which has been extensively validated. The new procedure has been demonstrated in the design of a cranked arrow wing at Mach 2.4 with coarse- and fine-grid based computations performed with Euler and TLNS equations. The influence of the initial constraints on the geometry and aerodynamics of the optimized shape has been explored. Various final shapes generated for an identical initial problem formulation but with different optimization path options (coarse or fine grid, Euler or TLNS), have been aerodynamically evaluated via a common fine-grid TLNS-based analysis. The initial constraint conditions show significant bearing on the optimization results. Also, the results demonstrate that to produce an aerodynamically efficient design, it is imperative to include the viscous physics in the optimization procedure with the proper resolution. Based upon the present results, to better utilize the scarce computational resources, it is recommended that, a number of viscous coarse grid cases using either a preconditioned bi-conjugate gradient (PbCG) or an alternating-direction-implicit (ADI) method, should initially be employed to improve the optimization problem definition, the design space and initial shape. Optimized shapes should subsequently be analyzed using a high fidelity (viscous with fine-grid resolution) flow analysis to evaluate their true performance potential. Finally, a viscous fine-grid-based shape optimization should be conducted, using an ADI method, to accurately obtain the final optimized shape.

  7. Effects of different limestone particle sizes in the diet of broiler breeders post molting on their performance, egg quality, incubation results, and pre-starter performance of their progeny.

    PubMed

    Bueno, I J M; Surek, D; Rocha, C; Schramm, V G; Muramatsu, K; Dahlke, F; Maiorka, A

    2016-04-01

    An experiment was conducted to test the hypothesis that a coarse limestone diet improves productivity, reproductive performance and the calcium utilization of molted broiler breeders. In total, 640 broiler breeder females, 73-week-old and sixty-four 27-week-old cockerels, Cobb 500, were evaluated during 10 weeks, according to a randomized block design composed of 4 treatments with 8 replicates each. Treatments consisted of diets with the inclusion of 100% fine limestone-fine PS (0.2 mm GMD-geometric mean diameter); PS1: 30% fine limestone+70% limestone with 1.0 mm GMD; PS2: 30% fine limestone+70% limestone with 2.0 mm GMD; and PS3: 30% fine limestone+70% limestone with 3.0 mm GMD. Calcium retention in the gizzard of the breeders, bone characteristics, and breeder performance, egg characteristics, eggshell quality, incubation performance, chick quality and yield, chick pre-starter live performance, and chick bone characteristics were determined. There was no significant difference (P>0.05) in the rate of lay, percentage of non-settable eggs, egg weight, egg shape index, egg specific gravity, eggshell weight, thickness, and percentage hatchability and egg weight loss of broiler breeders fed with diets with different limestone particle sizes. The chick quality and yield, chick pre-starter live performance, and chick bone characteristics were not affected (P>0.05) by any of the limestone particle sizes. It was concluded that live and reproductive performance parameters of broiler breeders post molting is not affected by limestone particle size in the feed. © 2016 Poultry Science Association Inc.

  8. Fractionation of surface sediment fines based on a coupled sieve-SPLITT (split flow thin cell) method.

    PubMed

    Coppola, Laurent; Gustafsson, Orjan; Andersson, Per; Axelsson, Pär

    2005-05-01

    In traditional sediment grain-size separation using sieve technique, the bulk of the organic matter passes through the smallest mesh size (generally 38 microm) and is not further fractionated. In this study, a common sieve separation has therefore been coupled with an extra high capacity split flow thin cell fractionation (EHC-SPLITT) instrument to separate the bulk surface sediment not only into size-based sieve fractions (> 100, 63-100, 38-63 and < 38 microm) but particularly to further fractionate hydrodynamically the fine fraction (< 38 microm) using the EHC-SPLITT. Compared to the few previous studies using a smaller high capacity (HC) SPLITT cell, the EHC-SPLITT evaluated in detail here has several advantages (e.g., 23 times higher throughput and allowance for large particle diameters). First, the EHC-SPLITT was calibrated with particle standards. Then, its ability to fractionate fine surface sediments hydrodynamically was demonstrated with material from biogeochemically distinct regimes using two cutoff velocities (1 and 6 m d(-1)). The results from particle standards indicated a good agreement between theory and experiment and a satisfactory mass recovery for the sieve-SPLITT method (80-97%) was observed for sediment samples. The mass distributions revealed that particles < 38 microm were predominant (70-90%), indicating the large need for a technique such as the EHC-SPLITT to further fractionate the fine particles. There were clearly different compositions in the EHC-SPLITT-mediated sub-fractions of the sediment fines as indicated by analyses of organic and inorganic parameters (POC, Si, Fe and Al). The EHC-SPLITT technique has the potential to provide information of great utility to studies of benthic boundary layer transport and off-shelf export and how such processes fractionate geochemical signals.

  9. Molecular Mechanism by which Prominent Human Gut Bacteroidetes Utilize Mixed-Linkage Beta-Glucans, Major Health-Promoting Cereal Polysaccharides.

    PubMed

    Tamura, Kazune; Hemsworth, Glyn R; Déjean, Guillaume; Rogers, Theresa E; Pudlo, Nicholas A; Urs, Karthik; Jain, Namrata; Davies, Gideon J; Martens, Eric C; Brumer, Harry

    2017-10-10

    Microbial utilization of complex polysaccharides is a major driving force in shaping the composition of the human gut microbiota. There is a growing appreciation that finely tuned polysaccharide utilization loci enable ubiquitous gut Bacteroidetes to thrive on the plethora of complex polysaccharides that constitute "dietary fiber." Mixed-linkage β(1,3)/β(1,4)-glucans (MLGs) are a key family of plant cell wall polysaccharides with recognized health benefits but whose mechanism of utilization has remained unclear. Here, we provide molecular insight into the function of an archetypal MLG utilization locus (MLGUL) through a combination of biochemistry, enzymology, structural biology, and microbiology. Comparative genomics coupled with growth studies demonstrated further that syntenic MLGULs serve as genetic markers for MLG catabolism across commensal gut bacteria. In turn, we surveyed human gut metagenomes to reveal that MLGULs are ubiquitous in human populations globally, which underscores the importance of gut microbial metabolism of MLG as a common cereal polysaccharide. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  10. Diagnosis of Hepatocellular Carcinoma Complicating Liver Cirrhosis: Utility of Repeat Ultrasound-Guided Biopsy after Unsuccessful First Sampling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caturelli, Eugenio; Biasini, Elisabetta; Bartolucci, Francesca

    2002-08-15

    Purpose: To evaluate the utility of a second ultrasound-guided fine-needle biopsy of liver nodules thought to be hepatocellular carcinoma when the original biopsy has failed to provide a reliable diagnosis. Methods: Thirty-seven cirrhotic patients underwent ultrasound-guided fine-needle biopsy of liver nodules that were subsequently diagnosed as hepatocellular carcinoma. Each biopsy involved a single puncture with a 20 G cutting needle, which yielded pathologic material used both for cytologic and histologic studies. In 23 cases (mean diameter of nodules 48 mm) the biopsy furnished exclusively necrotic material (non-diagnostic subgroup); in the other 14 cases (mean diameter 26 mm) the biopsy yieldedmore » no neoplastic elements (false-negative subgroup). All 37 nodules were subjected to repeat biopsies performed in the same manner. Results: The repeat biopsies provided a diagnosis of hepatocellular carcinoma in six of the 23 patients from the non-diagnostic subgroup and in seven of the 14 in the false-negative subgroup. Overall, repeat biopsy produced a diagnostic gain of 35.1%. Conclusion: The chance of success with repeat biopsy of hepatocellular carcinoma is limited and may depend to some extent on the characteristics of the lesions (i.e., areas of necrosis in large nodules, well-differentiated cellular populations in small ones)« less

  11. Fine-needle aspiration cytology of postirradiation sarcomas, including angiosarcoma, with immunocytochemical confirmation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Silverman, J.F.; Lannin, D.L.; Larkin, E.W.

    1989-01-01

    Postirradiation sarcomas are an unusual but well-recognized late effect of cancer therapy. In this article, a fine-needle aspiration (FNA) series of four cases is presented. There were three female patients and one male patient, with an age range of 28-55 yr (mean, 41). Two of the patients were irradiated for uterine cervical carcinoma while the other two received irradiation for malignant lymphoma. The time interval to the development of the postirradiation sarcoma ranged from 10 to greater than 20 yr. There were a postirradiation synovial sarcoma of the buttock region, malignant fibrous histiocytoma of the bone (femur), and rhabdomyosarcoma andmore » angiosarcoma of the retroperitoneum. A spectrum of cytologic findings was encountered, reflecting the specific types of sarcomas. Immunocytochemical studies performed on the aspirated material from the angiosarcoma demonstrated the utility of immunoperoxidase stains for ULEX europaeus agglutinin-1 (UEA-1) and, to a lesser degree, factor VIII-related antigen antibody, confirming the vascular nature of this malignancy. The FNA findings from all four cases demonstrated cytologic features that allowed recognition of this unusual complication of irradiation treatment. This article confirms the utility of FNA cytology in following patients with previous malignancies and differentiating a postirradiation sarcoma from recurrent carcinoma.« less

  12. Goal selection versus process control in a brain-computer interface based on sensorimotor rhythms.

    PubMed

    Royer, Audrey S; He, Bin

    2009-02-01

    In a brain-computer interface (BCI) utilizing a process control strategy, the signal from the cortex is used to control the fine motor details normally handled by other parts of the brain. In a BCI utilizing a goal selection strategy, the signal from the cortex is used to determine the overall end goal of the user, and the BCI controls the fine motor details. A BCI based on goal selection may be an easier and more natural system than one based on process control. Although goal selection in theory may surpass process control, the two have never been directly compared, as we are reporting here. Eight young healthy human subjects participated in the present study, three trained and five naïve in BCI usage. Scalp-recorded electroencephalograms (EEG) were used to control a computer cursor during five different paradigms. The paradigms were similar in their underlying signal processing and used the same control signal. However, three were based on goal selection, and two on process control. For both the trained and naïve populations, goal selection had more hits per run, was faster, more accurate (for seven out of eight subjects) and had a higher information transfer rate than process control. Goal selection outperformed process control in every measure studied in the present investigation.

  13. cuBLASTP: Fine-Grained Parallelization of Protein Sequence Search on CPU+GPU.

    PubMed

    Zhang, Jing; Wang, Hao; Feng, Wu-Chun

    2017-01-01

    BLAST, short for Basic Local Alignment Search Tool, is a ubiquitous tool used in the life sciences for pairwise sequence search. However, with the advent of next-generation sequencing (NGS), whether at the outset or downstream from NGS, the exponential growth of sequence databases is outstripping our ability to analyze the data. While recent studies have utilized the graphics processing unit (GPU) to speedup the BLAST algorithm for searching protein sequences (i.e., BLASTP), these studies use coarse-grained parallelism, where one sequence alignment is mapped to only one thread. Such an approach does not efficiently utilize the capabilities of a GPU, particularly due to the irregularity of BLASTP in both execution paths and memory-access patterns. To address the above shortcomings, we present a fine-grained approach to parallelize BLASTP, where each individual phase of sequence search is mapped to many threads on a GPU. This approach, which we refer to as cuBLASTP, reorders data-access patterns and reduces divergent branches of the most time-consuming phases (i.e., hit detection and ungapped extension). In addition, cuBLASTP optimizes the remaining phases (i.e., gapped extension and alignment with trace back) on a multicore CPU and overlaps their execution with the phases running on the GPU.

  14. The role of fine-grained annotations in supervised recognition of risk factors for heart disease from EHRs.

    PubMed

    Roberts, Kirk; Shooshan, Sonya E; Rodriguez, Laritza; Abhyankar, Swapna; Kilicoglu, Halil; Demner-Fushman, Dina

    2015-12-01

    This paper describes a supervised machine learning approach for identifying heart disease risk factors in clinical text, and assessing the impact of annotation granularity and quality on the system's ability to recognize these risk factors. We utilize a series of support vector machine models in conjunction with manually built lexicons to classify triggers specific to each risk factor. The features used for classification were quite simple, utilizing only lexical information and ignoring higher-level linguistic information such as syntax and semantics. Instead, we incorporated high-quality data to train the models by annotating additional information on top of a standard corpus. Despite the relative simplicity of the system, it achieves the highest scores (micro- and macro-F1, and micro- and macro-recall) out of the 20 participants in the 2014 i2b2/UTHealth Shared Task. This system obtains a micro- (macro-) precision of 0.8951 (0.8965), recall of 0.9625 (0.9611), and F1-measure of 0.9276 (0.9277). Additionally, we perform a series of experiments to assess the value of the annotated data we created. These experiments show how manually-labeled negative annotations can improve information extraction performance, demonstrating the importance of high-quality, fine-grained natural language annotations. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Virtual plate pre-bending for the long bone fracture based on axis pre-alignment.

    PubMed

    Liu, Bin; Luo, Xinjian; Huang, Rui; Wan, Chao; Zhang, Bingbing; Hu, Weihua; Yue, Zongge

    2014-06-01

    In this paper, a modeling and visualizing system for assisting surgeons in correctly registering for the closed fracture reduction surgery is presented. By using this system, the geometric parameters of the target fixation plate before the long bone fracture operation can be obtained. The main processing scheme consists of following steps: firstly (image data process), utilize the Curvelet transform to denoise the CT images of fracture part and then reconstruct the 3D models of the broken bones. Secondly (pre-alignment), extract the axial lines of the broken bones and spatially align them. Then drive the broken bone models to be pre-aligned. Thirdly (mesh segmentation), a method based on vertex normal feature is utilized to obtain the broken bone cross-sections mesh models. Fourthly (fine registration), the ICP (Iterative Closest Point) algorithm is used to register the cross-sections and the broken bone models are driven to achieve the fine registration posture. Lastly (plate fitting), an accurate NURBS surface fitting method is used to construct the virtual plate. The experiment proved that the obtained models of the pre-bended plates were closely bonded to the surface of the registered long bone models. Finally, the lengths, angles and other interested geometric parameters can be measured on the plate models. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. CD 99 immunocytochemistry in solid pseudopapillary tumor of pancreas: A study on fine-needle aspiration cytology smears.

    PubMed

    Ghosh, Ranajoy; Mallik, Saumya R; Mathur, Sandeep R; Iyer, Venkateswaran K

    2013-07-01

    Solid pseudopapillary tumor of pancreas (SPTP) is a rare pancreatic tumor of uncertain histogenesis usually affecting young women. Though these tumors have characteristic cytomorphology, it is sometimes difficult to differentiate them from neuroendocrine tumors of the pancreas. We reviewed cases of SPTP to delineate the diagnostic cytological features and also observed utility of CD 99 (MIC 2) immunostaining to aid in the diagnosis of this tumor. This study was designed to demonstrate the utility of CD 99 immunostaining along with cytological features for making a pre-operative diagnosis and delineating it from the neuroendocrine tumor of pancreas which is a close mimic. Cytomorphological features of 11 cases of solid pseudopapillary neoplasm diagnosed by pre-operative fine-needle aspiration cytology (FNAC) at our institute were reviewed. Immunocytochemistry for CD 99 was also performed on the smears. All the cases had cellular smears with monomorphic cells lying singly, as loosely cohesive clusters as well as forming delicate pseudopapillae. Presence of intra and extra-cellular basement membrane material, background foamy macrophages and nuclear grooves were the other salient features. Immunocytochemistry for CD 99 could be performed on eight cases and demonstrated typical paranuclear dot-like positivity. Pre-operative early diagnosis of SPTP can be made by FNAC which can further be aided by CD 99 immunocytochemistry.

  17. Electrodes and electrochemical storage cells utilizing tin-modified active materials

    DOEpatents

    Anani, Anaba; Johnson, John; Lim, Hong S.; Reilly, James; Schwarz, Ricardo; Srinivasan, Supramaniam

    1995-01-01

    An electrode has a substrate and a finely divided active material on the substrate. The active material is ANi.sub.x-y-z Co.sub.y Sn.sub.z, wherein A is a mischmetal or La.sub.1-w M.sub.w, M is Ce, Nd, or Zr, w is from about 0.05 to about 1.0, x is from about 4.5 to about 5.5, y is from 0 to about 3.0, and z is from about 0.05 to about 0.5. An electrochemical storage cell utilizes such an electrode as the anode. The storage cell further has a cathode, a separator between the cathode and the anode, and an electrolyte.

  18. Energy management system turns data into market info

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Traynor, P.J.; Ackerman, W.J.

    1996-09-01

    The designers claim that Wisconsin Power & Light Co`s new energy management system is the first system of its type in the world in terms of the comprehensiveness and scope of its stored and retrievable data. Furthermore, the system`s link to the utility`s generating assets enables powerplant management to dispatch generation resources based on up-to-date unit characteristics. That means that the new system gives WP&L a competitive tool to optimize operations as well as fine-tune its EMS based on timely load and unit response information. Additionally, the EMS gives WP&L insight into the complex issues related to the unbundling ofmore » generation resources.« less

  19. Solar energy harvesting by magnetic-semiconductor nanoheterostructure in water treatment technology.

    PubMed

    Mahmoodi, Vahid; Bastami, Tahereh Rohani; Ahmadpour, Ali

    2018-03-01

    Photocatalytic degradation of toxic organic pollutants in the wastewater using dispersed semiconductor nanophotocatalysts has a number of advantages such as high activity, cost effectiveness, and utilization of free solar energy. However, it is difficult to recover and recycle nanophotocatalysts since the fine dispersed nanoparticles are easily suspended in waters. Furthermore, a large amount of photocatalysts will lead to color contamination. Thus, it is necessary to prepare photocatalysts with easy separation for the reusable application. To take advantage of high photocatalysis activity and reusability, magnetic photocatalysts with separation function were utilized. In this review, the photocatalytic principle, structure, and application of the magnetic-semiconductor nanoheterostructure photocatalysts under solar light are evaluated. Graphical abstract ᅟ.

  20. Annealing Effects on Microstructure and Mechanical Properties of Ultrafine-Grained Al Composites Reinforced with Nano-Al2O3 by Rotary Swaging

    NASA Astrophysics Data System (ADS)

    Chen, Cunguang; Wang, Wenwen; Guo, Zhimeng; Sun, Chunbao; Volinsky, Alex A.; Paley, Vladislav

    2018-03-01

    Microstructure evolution and variations in mechanical properties of Al-Al2O3 nanocomposite produced by powder metallurgy were investigated and compared with commercially pure aluminum (Al-1050) after furnace annealing. Fine gas-atomized Al powder compacts were first sintered in flowing nitrogen, subsequently consolidated into wires by rotary swaging and eventually annealed at 300 and 500 °C for 24 h each. Scanning and transmission electron microscopy with energy-dispersive spectroscopy was utilized to document the microstructure evolution. Rotary swaging was proven to lead to a marked decrease in grain size. After heavy swaging to true deformation degree of φ = 6 and annealing at 500 °C, obvious recrystallization was observed at Al-1050's existing grain boundaries and the crystals began to grow perpendicular to the flow direction. In the Al-Al2O3 nanocomposite, fabricated from d 50 = 6 μm Al powder, recrystallization partially occurred, while grains were still extremely fine. Due to the dual role of fine-grained Al2O3 dispersion strengthening, the nanocomposite showed improved mechanical performance in terms of tensile strength, approximately twice higher than Al-1050 after annealing at 500 °C.

  1. Webly-Supervised Fine-Grained Visual Categorization via Deep Domain Adaptation.

    PubMed

    Xu, Zhe; Huang, Shaoli; Zhang, Ya; Tao, Dacheng

    2018-05-01

    Learning visual representations from web data has recently attracted attention for object recognition. Previous studies have mainly focused on overcoming label noise and data bias and have shown promising results by learning directly from web data. However, we argue that it might be better to transfer knowledge from existing human labeling resources to improve performance at nearly no additional cost. In this paper, we propose a new semi-supervised method for learning via web data. Our method has the unique design of exploiting strong supervision, i.e., in addition to standard image-level labels, our method also utilizes detailed annotations including object bounding boxes and part landmarks. By transferring as much knowledge as possible from existing strongly supervised datasets to weakly supervised web images, our method can benefit from sophisticated object recognition algorithms and overcome several typical problems found in webly-supervised learning. We consider the problem of fine-grained visual categorization, in which existing training resources are scarce, as our main research objective. Comprehensive experimentation and extensive analysis demonstrate encouraging performance of the proposed approach, which, at the same time, delivers a new pipeline for fine-grained visual categorization that is likely to be highly effective for real-world applications.

  2. Positioning performance of a maglev fine positioning system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wronosky, J.B.; Smith, T.G.; Jordan, J.D.

    1996-12-01

    A wafer positioning system was recently developed by Sandia National Laboratories for an Extreme Ultraviolet Lithography (EUVL) research tool. The system, which utilizes a magnetically levitated fine stage to provide ultra-precise positioning in all six degrees of freedom, incorporates technological improvements resulting from four years of prototype development experience. System enhancements, implemented on a second generation design for an ARPA National Center for Advanced Information Component Manufacturing (NCAICM) project, introduced active structural control for the levitated structure of the system. Magnetic levitation (maglev) is emerging as an important technology for wafer positioning systems in advanced lithography applications. The advantages ofmore » maglev stem from the absence of physical contact. The resulting lack of friction enables accurate, fast positioning. Maglev systems are mechanically simple, accomplishing full six degree-of-freedom suspension and control with a minimum of moving parts. Power-efficient designs, which reduce the possibility of thermal distortion of the platen, are achievable. Manufacturing throughput will be improved in future systems with the addition of active structural control of the positioning stages. This paper describes the design, implementation, and functional capability of the maglev fine positioning system. Specifics regarding performance design goals and test results are presented.« less

  3. Registration of Laser Scanning Point Clouds: A Review.

    PubMed

    Cheng, Liang; Chen, Song; Liu, Xiaoqiang; Xu, Hao; Wu, Yang; Li, Manchun; Chen, Yanming

    2018-05-21

    The integration of multi-platform, multi-angle, and multi-temporal LiDAR data has become important for geospatial data applications. This paper presents a comprehensive review of LiDAR data registration in the fields of photogrammetry and remote sensing. At present, a coarse-to-fine registration strategy is commonly used for LiDAR point clouds registration. The coarse registration method is first used to achieve a good initial position, based on which registration is then refined utilizing the fine registration method. According to the coarse-to-fine framework, this paper reviews current registration methods and their methodologies, and identifies important differences between them. The lack of standard data and unified evaluation systems is identified as a factor limiting objective comparison of different methods. The paper also describes the most commonly-used point cloud registration error analysis methods. Finally, avenues for future work on LiDAR data registration in terms of applications, data, and technology are discussed. In particular, there is a need to address registration of multi-angle and multi-scale data from various newly available types of LiDAR hardware, which will play an important role in diverse applications such as forest resource surveys, urban energy use, cultural heritage protection, and unmanned vehicles.

  4. Registration of Laser Scanning Point Clouds: A Review

    PubMed Central

    Cheng, Liang; Chen, Song; Xu, Hao; Wu, Yang; Li, Manchun

    2018-01-01

    The integration of multi-platform, multi-angle, and multi-temporal LiDAR data has become important for geospatial data applications. This paper presents a comprehensive review of LiDAR data registration in the fields of photogrammetry and remote sensing. At present, a coarse-to-fine registration strategy is commonly used for LiDAR point clouds registration. The coarse registration method is first used to achieve a good initial position, based on which registration is then refined utilizing the fine registration method. According to the coarse-to-fine framework, this paper reviews current registration methods and their methodologies, and identifies important differences between them. The lack of standard data and unified evaluation systems is identified as a factor limiting objective comparison of different methods. The paper also describes the most commonly-used point cloud registration error analysis methods. Finally, avenues for future work on LiDAR data registration in terms of applications, data, and technology are discussed. In particular, there is a need to address registration of multi-angle and multi-scale data from various newly available types of LiDAR hardware, which will play an important role in diverse applications such as forest resource surveys, urban energy use, cultural heritage protection, and unmanned vehicles. PMID:29883397

  5. Replacement of Fine Aggregate by using Recyclable Materials in Paving Blocks

    NASA Astrophysics Data System (ADS)

    Koganti, Shyam Prakash; Hemanthraja, Kommineni; Sajja, Satish

    2017-08-01

    Cement concrete paving blocks are precast hard products complete out of cement concrete. The product is made in various sizes and shapes like square, round and rectangular blocks of different dimensions with designs for interlocking of adjacent tiles blocks. Several Research Works have been carried out in the past to study the possibility of utilizing waste materials and industrial byproducts in the manufacturing of paver blocks. Various industrial waste materials like quarry dust, glass powder, ceramic dust and coal dust are used as partial replacement of fine aggregate and assessed the strength parameters and compared the profit percentages after replacement with waste materials. Quarry dust can be replaced by 20% and beyond that the difference in strength is not much higher but considering cost we can replace upto 40% so that we can get a profit of almost 10%. Similarly we can replace glass powder and ceramic dust by 20% only beyond that there is decrement in strength and even with 20% replacement we can get 1.34 % and 2.42% of profit. Coal dust is not suitable for alternative material as fine aggregate as it reduces the strength.

  6. Modeling dynamics of western juniper under climate change in a semiarid ecosystem

    NASA Astrophysics Data System (ADS)

    Shrestha, R.; Glenn, N. F.; Flores, A. N.

    2013-12-01

    Modeling future vegetation dynamics in response to climate change and disturbances such as fire relies heavily on model parameterization. Fine-scale field-based measurements can provide the necessary parameters for constraining models at a larger scale. But the time- and labor-intensive nature of field-based data collection leads to sparse sampling and significant spatial uncertainties in retrieved parameters. In this study we quantify the fine-scale carbon dynamics and uncertainty of juniper woodland in the Reynolds Creek Experimental Watershed (RCEW) in southern Idaho, which is a proposed critical zone observatory (CZO) site for soil carbon processes. We leverage field-measured vegetation data along with airborne lidar and timeseries Landsat imagery to initialize a state-and-transition model (VDDT) and a process-based fire-model (FlamMap) to examine the vegetation dynamics in response to stochastic fire events and climate change. We utilize recently developed and novel techniques to measure biomass and canopy characteristics of western juniper at the individual tree scale using terrestrial and airborne laser scanning techniques in RCEW. These fine-scale data are upscaled across the watershed for the VDDT and FlamMap models. The results will immediately improve our understanding of fine-scale dynamics and carbon stocks and fluxes of woody vegetation in a semi-arid ecosystem. Moreover, quantification of uncertainty will also provide a basis for generating ensembles of spatially-explicit alternative scenarios to guide future land management decisions in the region.

  7. Volume and weight characteristics of a typical Douglas-fir/ western larch stand, Coram Experimental Forest, Montana

    Treesearch

    Robert E. Benson; Joyce A. Schlieter

    1980-01-01

    An over-mature Douglas-fir/western larch stand on the Coram Experimental Forest in Montana averaged about 7,300 ft3/acre (511 rn3/ha) of wood over 3 inches (7.62 cm) in diameter, and an additional 57 tons/acre (128/ha) of fine material, before harvest. After logging, using three different cutting methods and four different levels of utilization, wood residues ranged...

  8. Subpicosecond X rotations of atomic clock states

    NASA Astrophysics Data System (ADS)

    Song, Yunheung; Lee, Han-gyeol; Kim, Hyosub; Jo, Hanlae; Ahn, Jaewook

    2018-05-01

    We demonstrate subpicosecond-timescale population transfer between the pair of hyperfine ground states of atomic rubidium using a single laser-pulse. Our scheme utilizes the geometric and dynamic phases induced during Rabi oscillation through the fine-structure excited state to construct an X rotation gate for the hyperfine-state qubit system. The experiment performed with a femtosecond laser and cold rubidium atoms, in a magnetooptical trap, shows over 98% maximal population transfer between the clock states.

  9. The fine scale physical attributes of coarse woody debris and effects of surrounding stand structure on its utilization by ants (Hymenoptera: Formicidae) in British Columbia, Canada

    Treesearch

    Robert J. Higgins; B. Staffan Lindgren

    2006-01-01

    Coarse woody debris (CWD) is increasingly recognized in Canada for its contribution toward biodiversity. It is a particularly vital resource in subboreal forests as nesting habitat for ants (Formicidae). Wood, which has low specific heat, provides a thermally favorable environment in this cool climate. Ants contribute to the physical breakdown of wood, and colonies are...

  10. Fine-filter method for Raman lidar based on wavelength division multiplexing and fiber Bragg grating.

    PubMed

    Wang, Jun; Zheng, Jiao; Lu, Hong; Yan, Qing; Wang, Li; Liu, Jingjing; Hua, Dengxin

    2017-11-01

    Atmospheric temperature is one of the important parameters for the description of the atmospheric state. Most of the detection approaches to atmospheric temperature monitoring are based on rotational Raman scattering for better understanding atmospheric dynamics, thermodynamics, atmospheric transmission, and radiation. In this paper, we present a fine-filter method based on wavelength division multiplexing, incorporating a fiber Bragg grating in the visible spectrum for the rotational Raman scattering spectrum. To achieve high-precision remote sensing, the strong background noise is filtered out by using the secondary cascaded light paths. Detection intensity and the signal-to-noise ratio are improved by increasing the utilization rate of return signal form atmosphere. Passive temperature compensation is employed to reduce the temperature sensitivity of fiber Bragg grating. In addition, the proposed method provides a feasible solution for the filter system with the merits of miniaturization, high anti-interference, and high stability in the space-based platform.

  11. Landscape capability predicts upland game bird abundance and occurrence

    USGS Publications Warehouse

    Loman, Zachary G.; Blomberg, Erik J.; DeLuca, William; Harrison, Daniel J.; Loftin, Cyndy; Wood, Petra B.

    2017-01-01

    Landscape capability (LC) models are a spatial tool with potential applications in conservation planning. We used survey data to validate LC models as predictors of occurrence and abundance at broad and fine scales for American woodcock (Scolopax minor) and ruffed grouse (Bonasa umbellus). Landscape capability models were reliable predictors of occurrence but were less indicative of relative abundance at route (11.5–14.6 km) and point scales (0.5–1 km). As predictors of occurrence, LC models had high sensitivity (0.71–0.93) and were accurate (0.71–0.88) and precise (0.88 and 0.92 for woodcock and grouse, respectively). Models did not predict point-scale abundance independent of the ability to predict occurrence of either species. The LC models are useful predictors of patterns of occurrences in the northeastern United States, but they have limited utility as predictors of fine-scale or route-specific abundances. 

  12. Enhance the Quality of Crowdsensing for Fine-Grained Urban Environment Monitoring via Data Correlation

    PubMed Central

    Kang, Xu; Liu, Liang; Ma, Huadong

    2017-01-01

    Monitoring the status of urban environments, which provides fundamental information for a city, yields crucial insights into various fields of urban research. Recently, with the popularity of smartphones and vehicles equipped with onboard sensors, a people-centric scheme, namely “crowdsensing”, for city-scale environment monitoring is emerging. This paper proposes a data correlation based crowdsensing approach for fine-grained urban environment monitoring. To demonstrate urban status, we generate sensing images via crowdsensing network, and then enhance the quality of sensing images via data correlation. Specifically, to achieve a higher quality of sensing images, we not only utilize temporal correlation of mobile sensing nodes but also fuse the sensory data with correlated environment data by introducing a collective tensor decomposition approach. Finally, we conduct a series of numerical simulations and a real dataset based case study. The results validate that our approach outperforms the traditional spatial interpolation-based method. PMID:28054968

  13. Science observations with the IUE using the one-gyro mode

    NASA Technical Reports Server (NTRS)

    Imhoff, C.; Pitts, R.; Arquilla, R.; Shrader, Chris R.; Perez, M. R.; Webb, J.

    1990-01-01

    The International Ultraviolet Explorer (IUE) attitude control system originally included an inertial reference package containing six gyroscopes for three axis stabilization. The science instrument includes a prime and redundant Field Error Sensor (FES) camera for target acquisition and offset guiding. Since launch, four of the six gyroscopes have failed. The current attitude control system utilizes the remaining two gyros and a Fine Sun Sensor (FSS) for three axis stabilization. When the next gyro fails, a new attitude control system will be uplinked which will rely on the remaining gyro and the FSS for general three axis stabilization. In addition to the FSS, the FES cameras will be required to assist in maintaining fine attitude control during target acquisition. This has required thoroughly determining the characteristics of the FES cameras and the spectrograph aperture plate as well as devising new target acquisition procedures. The results of this work are presented.

  14. Science observations with the IUE using the one-gyro mode

    NASA Technical Reports Server (NTRS)

    Imhoff, C.; Pitts, R.; Arquilla, R.; Shrader, C.; Perez, M.; Webb, J.

    1990-01-01

    The International Ultraviolet Explorer (IUE) attitude control system originally included an inertial reference package containing six gyroscopes for three axis stabilization. The science instrument includes a prime and redundant Field Error Sensor (FES) camera for target acquisition and offset guiding. Since launch, four of the six gyroscopes have failed. The current attitude control system utilizes the remaining two gyros and a Fine Sun Sensor (FSS) for three axis stabilization. When the next gyro fails, a new attitude control system will be uplinked, which will relay on the remaining gyro and the FSS for general three axis stabilization. In addition to the FSS, the FES cameras will be required to assist in maintaining fine attitude control during target acquisition. This has required thoroughly determining the characteristics of the FES cameras and the spectrograph aperture plate as well as devising new target acquisition procedures. The results of this work are presented.

  15. Spin Testing of Superalloy Disks With Dual Grain Structure

    NASA Technical Reports Server (NTRS)

    Hefferman, Tab M.

    2006-01-01

    This 24-month program was a joint effort between Allison Advanced Development Company (AADC), General Electric Aircraft (GEAE), and NASA Glenn Research Center (GRC). AADC led the disk and spin hardware design and analysis utilizing existing Rolls-Royce turbine disk forging tooling. Testing focused on spin testing four disks: two supplied by GEAE and two by AADC. The two AADC disks were made of Alloy 10, and each was subjected to a different heat treat process: one producing dual microstructure with coarse grain size at the rim and fine grain size at the bore and the other produced single fine grain structure throughout. The purpose of the spin tests was to provide data for evaluation of the impact of dual grain structure on disk overspeed integrity (yielding) and rotor burst criteria. The program culminated with analysis and correlation of the data to current rotor overspeed criteria and advanced criteria required for dual structure disks.

  16. Free thyroxine in needle washout after fine needle aspiration biopsy of toxic thyroid nodules.

    PubMed

    Raikov, Nikolai; Nonchev, Boyan; Chaushev, Borislav; Vjagova, Diyana; Todorov, Svetoslav; Bocheva, Yana; Malceva, Daniela; Vicheva, Snejinka; Raikova, Asyia; Argatska, Antoaneta; Raikov, Miroslav

    2016-01-01

    The main diagnostic tool for toxic adenomas (TA) is radionuclide imaging indicated in patients with evidence of thyroid nodules in combination with thyrotoxic syndrome. Thyroid ultrasound and fine-needle aspiration biopsy (FNAB) are widely used for the valuation of thyroid masses. There is no literature data concerning the utility of FNAB and related tests for the diagnosis of hyperfunctioning thyroid nodules. The purpose of this study is to determine the levels of free thyroxine (FT4) in the needle washout after FNAB of hot thyroid nodules. The results of our study show that the FT4 levels in needle washout from TA were significantly higher than the surrounding parenchyma and correlated with the hormonal changes in patients with thyroid hyperfunctioning nodules. Further studies on a large number of patients are needed to refine the diagnostic value of this method and evaluate its importance in quantitative risk assessment of thyroid autonomy.

  17. Fine pattern replication on 10 x 10-mm exposure area using ETS-1 laboratory tool in HIT

    NASA Astrophysics Data System (ADS)

    Hamamoto, K.; Watanabe, Takeo; Hada, Hideo; Komano, Hiroshi; Kishimura, Shinji; Okazaki, Shinji; Kinoshita, Hiroo

    2002-07-01

    Utilizing ETS-1 laboratory tool in Himeji Institute of Technology (HIT), as for the fine pattern replicated by using the Cr mask in static exposure, it is replicated in the exposure area of 10 mm by 2 mm in size that the line and space pattern width of 60 nm, the isolated line pattern width of 40 nm, and hole pattern width of 150 nm. According to the synchronous scanning of the mass and wafer with EUVL laboratory tool with reduction optical system which consisted of three-aspherical-mirror in the NewSUBARU facilities succeeded in the line of 60 nm and the space pattern formation in the exposure region of 10mm by 10mm. From the result of exposure characteristics for positive- tone resist for KrF and EB, KrF chemically amplified resist has better characteristics than EB chemically amplified resist.

  18. A voltage-dependent chloride channel fine-tunes photosynthesis in plants

    PubMed Central

    Herdean, Andrei; Teardo, Enrico; Nilsson, Anders K.; Pfeil, Bernard E.; Johansson, Oskar N.; Ünnep, Renáta; Nagy, Gergely; Zsiros, Ottó; Dana, Somnath; Solymosi, Katalin; Garab, Győző; Szabó, Ildikó; Spetea, Cornelia; Lundin, Björn

    2016-01-01

    In natural habitats, plants frequently experience rapid changes in the intensity of sunlight. To cope with these changes and maximize growth, plants adjust photosynthetic light utilization in electron transport and photoprotective mechanisms. This involves a proton motive force (PMF) across the thylakoid membrane, postulated to be affected by unknown anion (Cl−) channels. Here we report that a bestrophin-like protein from Arabidopsis thaliana functions as a voltage-dependent Cl− channel in electrophysiological experiments. AtVCCN1 localizes to the thylakoid membrane, and fine-tunes PMF by anion influx into the lumen during illumination, adjusting electron transport and the photoprotective mechanisms. The activity of AtVCCN1 accelerates the activation of photoprotective mechanisms on sudden shifts to high light. Our results reveal that AtVCCN1, a member of a conserved anion channel family, acts as an early component in the rapid adjustment of photosynthesis in variable light environments. PMID:27216227

  19. Characterisation and Processing of Some Iron Ores of India

    NASA Astrophysics Data System (ADS)

    Krishna, S. J. G.; Patil, M. R.; Rudrappa, C.; Kumar, S. P.; Ravi, B. P.

    2013-10-01

    Lack of process characterization data of the ores based on the granulometry, texture, mineralogy, physical, chemical, properties, merits and limitations of process, market and local conditions may mislead the mineral processing entrepreneur. The proper implementation of process characterization and geotechnical map data will result in optimized sustainable utilization of resource by processing. A few case studies of process characterization of some Indian iron ores are dealt with. The tentative ascending order of process refractoriness of iron ores is massive hematite/magnetite < marine black iron oxide sands < laminated soft friable siliceous ore fines < massive banded magnetite quartzite < laminated soft friable clayey aluminous ore fines < massive banded hematite quartzite/jasper < massive clayey hydrated iron oxide ore < manganese bearing iron ores massive < Ti-V bearing magnetite magmatic ore < ferruginous cherty quartzite. Based on diagnostic process characterization, the ores have been classified and generic process have been adopted for some Indian iron ores.

  20. Seebeck effect on a weak link between Fermi and non-Fermi liquids

    NASA Astrophysics Data System (ADS)

    Nguyen, T. K. T.; Kiselev, M. N.

    2018-02-01

    We propose a model describing Seebeck effect on a weak link between two quantum systems with fine-tunable ground states of Fermi and non-Fermi liquid origin. The experimental realization of the model can be achieved by utilizing the quantum devices operating in the integer quantum Hall regime [Z. Iftikhar et al., Nature (London) 526, 233 (2015), 10.1038/nature15384] designed for detection of macroscopic quantum charged states in multichannel Kondo systems. We present a theory of thermoelectric transport through hybrid quantum devices constructed from quantum-dot-quantum-point-contact building blocks. We discuss pronounced effects in the temperature and gate voltage dependence of thermoelectric power associated with a competition between Fermi and non-Fermi liquid behaviors. High controllability of the device allows to fine tune the system to different regimes described by multichannel and multi-impurity Kondo models.

  1. Feasibility Assessment of a Fine-Grained Access Control Model on Resource Constrained Sensors.

    PubMed

    Uriarte Itzazelaia, Mikel; Astorga, Jasone; Jacob, Eduardo; Huarte, Maider; Romaña, Pedro

    2018-02-13

    Upcoming smart scenarios enabled by the Internet of Things (IoT) envision smart objects that provide services that can adapt to user behavior or be managed to achieve greater productivity. In such environments, smart things are inexpensive and, therefore, constrained devices. However, they are also critical components because of the importance of the information that they provide. Given this, strong security is a requirement, but not all security mechanisms in general and access control models in particular are feasible. In this paper, we present the feasibility assessment of an access control model that utilizes a hybrid architecture and a policy language that provides dynamic fine-grained policy enforcement in the sensors, which requires an efficient message exchange protocol called Hidra. This experimental performance assessment includes a prototype implementation, a performance evaluation model, the measurements and related discussions, which demonstrate the feasibility and adequacy of the analyzed access control model.

  2. Feasibility Assessment of a Fine-Grained Access Control Model on Resource Constrained Sensors

    PubMed Central

    Huarte, Maider; Romaña, Pedro

    2018-01-01

    Upcoming smart scenarios enabled by the Internet of Things (IoT) envision smart objects that provide services that can adapt to user behavior or be managed to achieve greater productivity. In such environments, smart things are inexpensive and, therefore, constrained devices. However, they are also critical components because of the importance of the information that they provide. Given this, strong security is a requirement, but not all security mechanisms in general and access control models in particular are feasible. In this paper, we present the feasibility assessment of an access control model that utilizes a hybrid architecture and a policy language that provides dynamic fine-grained policy enforcement in the sensors, which requires an efficient message exchange protocol called Hidra. This experimental performance assessment includes a prototype implementation, a performance evaluation model, the measurements and related discussions, which demonstrate the feasibility and adequacy of the analyzed access control model. PMID:29438338

  3. Design of Far-Red Sensitizing Squaraine Dyes Aiming Towards the Fine Tuning of Dye Molecular Structure.

    PubMed

    Morimoto, Takuya; Fujikawa, Naotaka; Ogomi, Yuhei; Pandey, Shyam S; Ma, Tingli; Hayase, Shuzi

    2016-04-01

    Model squaraine dyes having sharp and narrow absorptions mainly in the far-red wavelength region has been logically designed, synthesized and used for their application as sensitizer in the dyesensitized solar cells (DSSC). In order to have fine control on energetics, dyes having same mother core and alkyl chain length varying only in molecular symmetry and position of substituent were designed. It has been found that even keeping all other structural factor constant, only positional variation of substituent leads to not only in the variation of energetics by 0.1 eV but affects the photovoltaic characteristics also. Optimum concentration of dye de-aggregating agent was found to be 100 times with respect to the sensitizing dye concentration. Amongst dyes utilized in this work best performance was obtained for unsymmetrical dye SQ-40 giving a photoconversion efficiency of 4.01% under simulated solar irradiation at global AM 1.5.

  4. Fog Harvesting with Harps.

    PubMed

    Shi, Weiwei; Anderson, Mark J; Tulkoff, Joshua B; Kennedy, Brook S; Boreyko, Jonathan B

    2018-04-11

    Fog harvesting is a useful technique for obtaining fresh water in arid climates. The wire meshes currently utilized for fog harvesting suffer from dual constraints: coarse meshes cannot efficiently capture microscopic fog droplets, whereas fine meshes suffer from clogging issues. Here, we design and fabricate fog harvesters comprising an array of vertical wires, which we call "fog harps". Under controlled laboratory conditions, the fog-harvesting rates for fog harps with three different wire diameters were compared to conventional meshes of equivalent dimensions. As expected for the mesh structures, the mid-sized wires exhibited the largest fog collection rate, with a drop-off in performance for the fine or coarse meshes. In contrast, the fog-harvesting rate continually increased with decreasing wire diameter for the fog harps due to efficient droplet shedding that prevented clogging. This resulted in a 3-fold enhancement in the fog-harvesting rate for the harp design compared to an equivalent mesh.

  5. The role of fine needle aspiration cytology in medical-surgical missions.

    PubMed

    Reyes, Cesar V; Reyes, Elisa A

    2009-01-01

    To relate a 6-year, short-term experience of utilizing fine needle aspiration cytology (FNAC) during medical-surgical missions in the impoverished areas of the Philippines. FNAC is a simple, accurate, fast and economical procedure and requires the simplest devices to implement. During medical-surgical missions to the poorest areas in the Third World countries, where there is almost complete lack of tissue processing and frozen section evaluation, and scarcity of laboratory testing, FNAC becomes a practical technique to use. FNAC in these situations plays an important role as an alternative diagnostic modality to surgery. Our week-long mission experience for 6 different years of successful application of FNAC is described. While the mission volunteers have gained extremely rewarding experience in these limited mission works, FNAC has proven to be a very useful adjunct in the delivery of short-term health care during medical-surgical treatment even in a less-than-ideal setting.

  6. Two-color immunostaining of liver fine needle aspiration biopsies with CD34 and carcinoembryonic antigen. Potential utilization in the diagnosis of primary hepatocellular carcinoma vs. metastatic tumor.

    PubMed

    Yoder, Michael; Zimmerman, Robert L; Bibbo, Marluce

    2004-04-01

    To examine immunohistochemical staining of cell block material with antibodies against vascular marker CD34 and polyclonal carcinoembryonic antigen (pCEA) for their clinical utility as part of a 2-color staining protocol in fine needle aspiration (FNA) biopsy of liver masses to distinguish metastases from primary hepatocellular carcinoma (HCC). The authors obtained cell block material from 96 liver FNAs and performed simultaneous (i.e., "dual-color") immunohistochemical staining utilizing antibodies against vascular marker CD34 and pCEA. Cases were blinded and evaluated by the authors for staining pattern and intensity. A consensus was obtained, the results were unblinded, and the diagnoses were correlated. After staining, 89 cases had sufficient tissue for evaluation. Of the 19 HCC cases, 16 (84%) showed peripheral staining with CD34, and 13 (68%) showed a canalicular or mixed canalicular-cytoplasmic staining pattern for pCEA. Thirteen cases (68%) showed staining for both antigens. All HCC exhibited immunostaining for at least 1 antibody in an appropriate staining pattern. Of the 67 cases of metastatic malignancy, 5 (7%) showed a predominantly transgressing pattern of CD34 staining, 43 (64%) showed a predominantly cytoplasmic or mixed cytoplasmic-canalicular pattern of pCEA staining, and 2 cases (3%) showed staining for both antigens in a transgressing CD34 pattern and cytoplasmic pCEA pattern. None of the 3 normal liver tissue blocks showed staining with either antigen. Two-color immunohistochemical staining of liver cell block material obtained by FNA with antibodies to CD34 and pCEA can be helpful in differentiating metastatic tumors vs. primary HCC.

  7. Comparative effect of lunar fines and terrestrtrial ash on the growth of a blue-green alga and germinating radish seeds

    NASA Technical Reports Server (NTRS)

    Ridley, E. J.

    1983-01-01

    Although it is understood that photosynthetic organisms will be required as components of a closed ecological life support system (CELSS) for a manned lunar based, a basic problem is to identify organisms best capable of utilizing lunar regolith materials. Also, there is need to determine what nutrient supplements have to be added to lunar soils, and at what levels in order to promote high bio-mass production.

  8. Evaluation of Particle Counter Technology for Detection of Fuel Contamination Detection Utilizing Fuel System Supply Point

    DTIC Science & Technology

    2014-06-19

    product used as a diesel product for ground use (1). Free water contamination (droplets) may appear as fine droplets or slugs of water in the fuel...methods and test procedures for the calibration and use of automatic particle counters. The transition of this technology to the fuel industry is...UNCLASSIFIED 6 UNCLASSIFIED Receipt Vehicle Fuel Tank Fuel Injector Aviation Fuel DEF (AUST) 5695B 18/16/13 Parker 18

  9. Endoscopic ultrasound guided brush/fine-needle aspiration cytology: A 15-month study.

    PubMed

    Tummidi, Santosh; Kothari, Kanchan; Sathe, Pragati; Agnihotri, Mona; Fernandes, Gwendolyn; Naik, Leena; Jain, Aleena; Chaturvedi, Rachana

    2018-06-01

    Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has become increasingly popular for the diagnosis and staging of gastrointestinal diseases and peri-gastrointestinal lesions. The application of FNA/Brush has dramatically expanded the clinical utility of EUS. To evaluate the diagnostic accuracy, study the spectrum of lesions encountered in EUS-FNAC/brush cytology of gastrointestinal and peri-gastrointestinal lesions. Total of 124 patients during the period from August 2015 to November 2016 was included in the study. Routine staining was done. A total of 124 cases were studied with 86% (107 cases) being satisfactory for evaluation. M:F ratio was 1:1.03, mean age of 50.5 years. The most common site was common bile duct (CBD) (37%) followed by lymph node (21%), pancreas (17.7%), esophagus (17%), stomach (3.5%), liver (1.8%), gallbladder (1%), and spleen (1%). In total, 53.4% lesions were benign, in 6.5% atypical cells were seen, 12.1% were suspicious for malignancy, and 28% cases were positive for malignancy. Follow-up was available in 102 cases with cyto-histopathological concordance rate of 90%. EUS-FNA/Brush is a reliable, sensitive, specific and minimally invasive way to establish a diagnosis. It can be utilized as a pre-operative procedure for the management of many intra-abdominal lesions and prevent unnecessary invasive procedures. © 2018 Wiley Periodicals, Inc.

  10. Comparison of motor delays in young children with fetal alcohol syndrome to those with prenatal alcohol exposure and with no prenatal alcohol exposure.

    PubMed

    Kalberg, Wendy O; Provost, Beth; Tollison, Sean J; Tabachnick, Barbara G; Robinson, Luther K; Eugene Hoyme, H; Trujillo, Phyllis M; Buckley, David; Aragon, Alfredo S; May, Philip A

    2006-12-01

    Researchers are increasingly considering the importance of motor functioning of children with fetal alcohol spectrum disorder (FASD). The purpose of this study was to assess the motor development of young children with fetal alcohol syndrome (FAS) to determine the presence and degree of delay in their motor skills and to compare their motor development with that of matched children without FAS. The motor development of 14 children ages 20 to 68 months identified with FAS was assessed using the Vineland Adaptive Behavior Scales (VABS). In addition, 2 comparison groups were utilized. Eleven of the children with FAS were matched for chronological age, gender, ethnicity, and communication age to: (1) 11 children with prenatal alcohol exposure who did not have FAS and (2) 11 matched children without any reported prenatal alcohol exposure. The motor scores on the VABS were compared among the 3 groups. Most of the young children with FAS in this study showed clinically important delays in their motor development as measured on the VABS Motor Domain, and their fine motor skills were significantly more delayed than their gross motor skills. In the group comparisons, the young children with FAS had significantly lower Motor Domain standard (MotorSS) scores than the children not exposed to alcohol prenatally. They also had significantly lower Fine Motor Developmental Quotients than the children in both the other groups. No significant group differences were found in gross motor scores. For MotorSS scores and Fine Motor Developmental Quotients, the means and standard errors indicated a continuum in the scores from FAS to prenatal alcohol exposure to nonexposure. These findings strongly suggest that all young children with FAS should receive complete developmental evaluations that include assessment of their motor functioning, to identify problem areas and provide access to developmental intervention programs that target deficit areas such as fine motor skills. Fine motor delays in children with FAS may be related to specific neurobehavioral deficits that affect fine motor skills. The findings support the concept of an FASD continuum in some areas of motor development.

  11. Water Utility Lime Sludge Reuse – An Environmental Sorbent ...

    EPA Pesticide Factsheets

    Lime sludge can be used as an environmental sorbent to remove sulfur dioxide (SO2) and acid gases, by the ultra-fine CaCO3 particles, and to sequester mercury and other heavy metals, by the Natural Organic Matter and residual activated carbon. The laboratory experimental set up included a simulated flue gas preparation unit, a lab-scale wet scrubber, and a mercury analyzer system. The influent mercury concentration was based on a range from 22 surveyed power plants. The reactivity of the lime sludge sample for acid neutralization was determined using a method similar to method ASTM C1318-95. Similar experiments were conducted using reagent calcium carbonate and calcium sulfate to obtain baseline data for comparing with the lime sludge test results. The project also evaluated the techno-economic feasibility and sustainable benefits of reusing lime softening sludge. If implemented on a large scale, this transformative approach for recycling waste materials from water treatment utilities at power generation utilities for environmental cleanup can save both water and power utilities millions of dollars. Huge amounts of lime sludge waste, generated from hundreds of water treatment utilities across the U.S., is currently disposed in landfills. This project evaluated a sustainable and economically-attractive approach to the use of lime sludge waste as a valuable resource for power generation utilities.

  12. 3D WHOLE-PROMINENCE FINE STRUCTURE MODELING. II. PROMINENCE EVOLUTION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gunár, Stanislav; Mackay, Duncan H.

    2015-10-20

    We use the new three-dimensional (3D) whole-prominence fine structure model to study the evolution of prominences and their fine structures in response to changes in the underlying photospheric magnetic flux distribution. The applied model combines a detailed 3D prominence magnetic field configuration with a realistic description of the prominence plasma distributed along multiple fine structures. In addition, we utilize an approximate Hα visualization technique to study the evolution of the visible cool prominence plasma both in emission (prominence) and absorption (filament). We show that the initial magnetic field configuration of the modeled prominence is significantly disturbed by the changing positionmore » of a single polarity of a magnetic bipole as the bipole is advected toward the main body of the filament. This leads to the creation of a barb, which becomes the dominant feature visible in the synthetic Hα images of both the prominence and filament views. The evolution of the bipole also creates conditions that lead to the disappearance and reappearance of large portions of the main body. We also show that an arch-like region containing a dark void (a bubble) can be naturally produced in the synthetic prominence Hα images. While not visible in terms of the magnetic field lines, it is due to a lack of Hα emission from low-pressure, low-density plasma located in shallow magnetic dips lying along the lines of sight intersecting the dark void. In addition, a quasi-vertical small-scale feature consisting of short and deep dips, piled one above the other, is produced.« less

  13. Fine-mapping diabetes-related traits, including insulin resistance, in heterogeneous stock rats

    PubMed Central

    Holl, Katie L.; Oreper, Daniel; Xie, Yuying; Tsaih, Shirng-Wern; Valdar, William

    2012-01-01

    Type 2 diabetes (T2D) is a disease of relative insulin deficiency resulting from both insulin resistance and beta cell failure. We have previously used heterogeneous stock (HS) rats to fine-map a locus for glucose tolerance. We show here that glucose intolerance in the founder strains of the HS colony is mediated by different mechanisms: insulin resistance in WKY and an insulin secretion defect in ACI, and we demonstrate a high degree of variability for measures of insulin resistance and insulin secretion in HS rats. As such, our goal was to use HS rats to fine-map several diabetes-related traits within a region on rat chromosome 1. We measured blood glucose and plasma insulin levels after a glucose tolerance test in 782 male HS rats. Using 97 SSLP markers, we genotyped a 68 Mb region on rat chromosome 1 previously implicated in glucose and insulin regulation. We used linkage disequilibrium mapping by mixed model regression with inferred descent to identify a region from 198.85 to 205.9 that contains one or more quantitative trait loci (QTL) for fasting insulin and a measure of insulin resistance, the quantitative insulin sensitivity check index. This region also encompasses loci identified for fasting glucose and Insulin_AUC (area under the curve). A separate <3 Mb QTL was identified for body weight. Using a novel penalized regression method we then estimated effects of alternative haplotype pairings under each locus. These studies highlight the utility of HS rats for fine-mapping genetic loci involved in the underlying causes of T2D. PMID:22947656

  14. Ensemble-Based Source Apportionment of Fine Particulate Matter and Emergency Department Visits for Pediatric Asthma

    PubMed Central

    Gass, Katherine; Balachandran, Sivaraman; Chang, Howard H.; Russell, Armistead G.; Strickland, Matthew J.

    2015-01-01

    Epidemiologic studies utilizing source apportionment (SA) of fine particulate matter have shown that particles from certain sources might be more detrimental to health than others; however, it is difficult to quantify the uncertainty associated with a given SA approach. In the present study, we examined associations between source contributions of fine particulate matter and emergency department visits for pediatric asthma in Atlanta, Georgia (2002–2010) using a novel ensemble-based SA technique. Six daily source contributions from 4 SA approaches were combined into an ensemble source contribution. To better account for exposure uncertainty, 10 source profiles were sampled from their posterior distributions, resulting in 10 time series with daily SA concentrations. For each of these time series, Poisson generalized linear models with varying lag structures were used to estimate the health associations for the 6 sources. The rate ratios for the source-specific health associations from the 10 imputed source contribution time series were combined, resulting in health associations with inflated confidence intervals to better account for exposure uncertainty. Adverse associations with pediatric asthma were observed for 8-day exposure to particles generated from diesel-fueled vehicles (rate ratio = 1.06, 95% confidence interval: 1.01, 1.10) and gasoline-fueled vehicles (rate ratio = 1.10, 95% confidence interval: 1.04, 1.17). PMID:25776011

  15. Development in children with achondroplasia: a prospective clinical cohort study.

    PubMed

    Ireland, Penelope J; Donaghey, Samantha; McGill, James; Zankl, Andreas; Ware, Robert S; Pacey, Verity; Ault, Jenny; Savarirayan, Ravi; Sillence, David; Thompson, Elizabeth; Townshend, Sharron; Johnston, Leanne M

    2012-06-01

    Achondroplasia is characterized by delays in the development of communication and motor skills. While previously reported developmental profiles exist across gross motor, fine motor, feeding, and communication skills, there has been no prospective study of development across multiple areas simultaneously. This Australasian population-based study utilized a prospective questionnaire to quantify developmental data for skills in children born from 2000 to 2009. Forty-eight families from Australia and New Zealand were asked to report every 3 months on their child's attainment of 41 milestones. Results include reference to previously available prospective information. Information from questionnaires was used to develop an achondroplasia-specific developmental recording form. The 25th, 50th, 75th, and 90th centiles were plotted to offer clear guidelines for development across gross motor, fine motor, feeding, and communication skills in children with achondroplasia. Consistent with results from previous research, children with achondroplasia are delayed in development of gross motor and ambulatory skills. Young children with achondroplasia demonstrate a number of unique movement strategies that appear compensatory for the biomechanical changes. While delays were seen in development of later communication items, there were fewer delays seen across development of early communication, fine motor, and feeding skills. © The Authors. Developmental Medicine & Child Neurology © 2012 Mac Keith Press.

  16. Object-Based Paddy Rice Mapping Using HJ-1A/B Data and Temporal Features Extracted from Time Series MODIS NDVI Data

    PubMed Central

    Singha, Mrinal; Wu, Bingfang; Zhang, Miao

    2016-01-01

    Accurate and timely mapping of paddy rice is vital for food security and environmental sustainability. This study evaluates the utility of temporal features extracted from coarse resolution data for object-based paddy rice classification of fine resolution data. The coarse resolution vegetation index data is first fused with the fine resolution data to generate the time series fine resolution data. Temporal features are extracted from the fused data and added with the multi-spectral data to improve the classification accuracy. Temporal features provided the crop growth information, while multi-spectral data provided the pattern variation of paddy rice. The achieved overall classification accuracy and kappa coefficient were 84.37% and 0.68, respectively. The results indicate that the use of temporal features improved the overall classification accuracy of a single-date multi-spectral image by 18.75% from 65.62% to 84.37%. The minimum sensitivity (MS) of the paddy rice classification has also been improved. The comparison showed that the mapped paddy area was analogous to the agricultural statistics at the district level. This work also highlighted the importance of feature selection to achieve higher classification accuracies. These results demonstrate the potential of the combined use of temporal and spectral features for accurate paddy rice classification. PMID:28025525

  17. Enzymatic hydrolysis of anchovy fine powder at high and ambient pressure, and characterization of the hydrolyzates.

    PubMed

    Kim, Namsoo; Son, So-Hee; Maeng, Jin-Soo; Cho, Yong-Jin; Kim, Chong-Tai

    2016-02-01

    At specific conditions of high pressure, the stability and activity of some enzymes are reportedly known to increase. The aim of this study was to apply pressure-tolerant proteases to hydrolyzing anchovy fine powder (AFP) and to determine product characteristics of the resultant hydrolyzates. Anchovy fine powder enzyme hydrolyzates (AFPEHs) were produced at 300 MPa and ambient pressure using combinations of Flavourzyme 500MG, Alcalase 2.4L, Marugoto E and Protamex. When the same protease combination was used for hydrolysis, the contents of total soluble solids, total water-soluble nitrogen and trichloroacetic acid-soluble nitrogen in the AFPEHs produced at 300 MPa were conspicuously higher than those in the AFPEHs produced at ambient pressure. This result and electrophoretic characteristics indicated that the high-pressure process of this study accelerates protein hydrolysis compared with the ambient-pressure counterpart. Most peptides in the hydrolyzates obtained at 300 MPa had molecular masses less than 5 kDa. Functionality, sensory characteristics and the content of total free amino acids of selected hydrolyzates were also determined. The high-pressure hydrolytic process utilizing pressure-tolerant proteases was found to be an efficient method for producing protein hydrolyzates with good product characteristics. © 2015 Society of Chemical Industry.

  18. Chemical and carbon-13 cross-polarization magic-angle spinning nuclear magnetic resonance characterization of logyard fines from British Columbia.

    PubMed

    Preston, C M; Forrester, P D

    2004-01-01

    Phasing out beehive burners and rising costs for landfilling have increased the need to widen options for utilization of the smaller size fractions of woody wastes generated during log handling and sawmilling in British Columbia. We characterized several size classes of logyard fines up to 16 mm sampled from coastal and interior operations. Total C, total N, ash, and condensed tannin concentrations were consistent with properties derived largely from wood, with varying proportions of bark and mixing with mineral soil. Especially for < 3-mm fractions, the latter resulted in high ash contents that would make them unsuitable for fuel. Solid-state 13C cross-polarization magic-angle spinning (CPMAS) nuclear magnetic resonance (NMR) spectra were consistent with the chemical data, with high O-alkyl intensity and similarity to naturally occurring woody forest floor; no samples were high in aromatic or phenolic C. Aqueous extracts of two < 16-mm fines, which accounted for only a small proportion of the total C, were enriched in alkyl C and had low or undetectable tannins. Application to forest sites might cause short-term immobilization of N, but also might include possible longer-term benefits from reduction of N loss after harvesting and restoration of soil organic matter in degraded sites.

  19. Object-Based Paddy Rice Mapping Using HJ-1A/B Data and Temporal Features Extracted from Time Series MODIS NDVI Data.

    PubMed

    Singha, Mrinal; Wu, Bingfang; Zhang, Miao

    2016-12-22

    Accurate and timely mapping of paddy rice is vital for food security and environmental sustainability. This study evaluates the utility of temporal features extracted from coarse resolution data for object-based paddy rice classification of fine resolution data. The coarse resolution vegetation index data is first fused with the fine resolution data to generate the time series fine resolution data. Temporal features are extracted from the fused data and added with the multi-spectral data to improve the classification accuracy. Temporal features provided the crop growth information, while multi-spectral data provided the pattern variation of paddy rice. The achieved overall classification accuracy and kappa coefficient were 84.37% and 0.68, respectively. The results indicate that the use of temporal features improved the overall classification accuracy of a single-date multi-spectral image by 18.75% from 65.62% to 84.37%. The minimum sensitivity (MS) of the paddy rice classification has also been improved. The comparison showed that the mapped paddy area was analogous to the agricultural statistics at the district level. This work also highlighted the importance of feature selection to achieve higher classification accuracies. These results demonstrate the potential of the combined use of temporal and spectral features for accurate paddy rice classification.

  20. Investigating selective transport and abrasion on an alluvial fan using quantitative grain size and shape analysis

    NASA Astrophysics Data System (ADS)

    Litwin, K. L.; Jerolmack, D. J.

    2011-12-01

    Selective sorting and abrasion are the two major fluvial processes that are attributed to the downstream fining of sediments in rivers and alluvial fans. Selective transport is the process by which smaller grains are preferentially transported downstream while larger grains are deposited closer to the source. Abrasion is defined by the production of fine sediments and sand that occurs by saltation of gravel, where particle-to-particle collisions supply the energy required to break apart grains. We hypothesize that abrasion results in the gradual fining of large grains and the production of fine sands and silts, while sorting accounts for the differences in transport of these two grain-size fractions produced from abrasion, thereby creating the abrupt gravel-sand transition observed in many channel systems. In this research, we explore both selective transport and abrasion processes on the Dog Canyon alluvial fan near Alamogordo, New Mexico. We complete an extensive grain size analysis down the main channel of the fan employing an image-based technique that utilizes an autocorrelation process. We also characterize changes in grain shape using standard shape parameters, as well as Fourier analysis, which allows the study of contributions of grain roughness on a variety of length scales. Sorting appears to dominate the upper portion of the fan; the grain-size distribution narrows moving downstream until reaching a point of equal mobility, at which point sorting ceases. Abrasion exerts a subtle but persistent effect on grains during transport down the fan. Shape analysis reveals that particles become more rounded by the removal of small-scale textural features, a process that is expected to only modestly influence grain size of gravel, but should produce significant quantities of sand. This study provides a better understanding of the importance of grain abrasion and sorting on the downstream fining of channel grains in an alluvial fan, as well as an improved knowledge about the abrupt gravel-sand transition observed in a majority of alluvial fans.

  1. Chromatin versus pathogens: the function of epigenetics in plant immunity.

    PubMed

    Ding, Bo; Wang, Guo-Liang

    2015-01-01

    To defend against pathogens, plants have developed a sophisticated innate immunity that includes effector recognition, signal transduction, and rapid defense responses. Recent evidence has demonstrated that plants utilize the epigenetic control of gene expression to fine-tune their defense when challenged by pathogens. In this review, we highlight the current understanding of the molecular mechanisms of histone modifications (i.e., methylation, acetylation, and ubiquitination) and chromatin remodeling that contribute to plant immunity against pathogens. Functions of key histone-modifying and chromatin remodeling enzymes are discussed.

  2. Centrifugal Size-Separation Sieve for Granular Materials

    NASA Technical Reports Server (NTRS)

    Walton, Otis (Inventor); Dreyer, Christopher (Inventor); Riedel, Edward (Inventor)

    2015-01-01

    A centrifugal sieve and method utilizes centrifugal force in rapidly-rotated cylindrical or conical screens as the primary body force contributing to size segregation. Within the centrifugal acceleration field, vibration and/or shearing flows are induced to facilitate size segregation and eventual separation of the fines from the coarse material. Inside a rotating cylindrical or conical screen, a separately-rotated screw auger blade can be used to transport material along the rotating cylinder or conical wall and to induce shearing in the material.

  3. Evaluation of Particle Counter Technology for Detection of Fuel Contamination Detection Utilizing Advanced Aviation Forward Area Refueling System

    DTIC Science & Technology

    2014-01-24

    8, Automatic Particle Counter, cleanliness, free water, Diesel 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT none 18. NUMBER OF...aircraft, or up to 10 mg/L for product used as a diesel product for ground use (1). Free water contamination (droplets) may appear as fine droplets or...published several methods and test procedures for the calibration and use of automatic particle counters. The transition of this technology to the fuel

  4. Smart Phase Tuning in Microwave Photonic Integrated Circuits Toward Automated Frequency Multiplication by Design

    NASA Astrophysics Data System (ADS)

    Nabavi, N.

    2018-07-01

    The author investigates the monitoring methods for fine adjustment of the previously proposed on-chip architecture for frequency multiplication and translation of harmonics by design. Digital signal processing (DSP) algorithms are utilized to create an optimized microwave photonic integrated circuit functionality toward automated frequency multiplication. The implemented DSP algorithms are formed on discrete Fourier transform and optimization-based algorithms (Greedy and gradient-based algorithms), which are analytically derived and numerically compared based on the accuracy and speed of convergence criteria.

  5. Sea-Ice Feature Mapping using JERS-1 Imagery

    NASA Technical Reports Server (NTRS)

    Maslanik, James; Heinrichs, John

    1994-01-01

    JERS-1 SAR and OPS imagery are examined in combination with other data sets to investigate the utility of the JERS-1 sensors for mapping fine-scale sea ice conditions. Combining ERS-1 C band and JERS-1 L band SAR aids in discriminating multiyear and first-year ice. Analysis of OPS imagery for a field site in the Canadian Archipelago highlights the advantages of OPS's high spatial and spectral resolution for mapping ice structure, melt pond distribution, and surface albedo.

  6. The Evaluation of Novel Bioactive Ingredients for Combat Ration Intermediate Moisture (IM) Products to Assure the Microbiological Safety

    DTIC Science & Technology

    2008-10-01

    bacterial inactivation ( Hiraki , 2000 and Hiraki et al., 2003). The exact mechanism of action is not well understood. Purasal®P is a combination of...coli O157:H7, Slamonella typhimurium and Listeria monocytogenes Journal of Food Science 70: M404-M408. Hiraki J. 2000. ε-polylysine; its...development and utilization. Fine Chem 29: 18-25. Hiraki J., Takafumi I., Ninomiya S., Seki H., Uohama K., Seki H., Kimura S., Yangimoto Y. and Barnett J

  7. Stacking Orientation Mediation of Pentacene and Derivatives for High Open-Circuit Voltage Organic Solar Cells.

    PubMed

    Chou, Chi-Ta; Lin, Chien-Hung; Tai, Yian; Liu, Chin-Hsin J; Chen, Li-Chyong; Chen, Kuei-Hsien

    2012-05-03

    In this Letter, we investigated the effect of the molecular stacking orientation on the open circuit voltage (VOC) of pentacene-based organic solar cells. Two functionalized pentacenes, namely, 6,13-diphenyl-pentacene (DP-penta) and 6,13-dibiphenyl-4-yl-pentacene (DB-penta), were utilized. Different molecular stacking orientations of the pentacene derivatives from the pristine pentacene were identified by angle-dependent near-edge X-ray absorption fine structure measurements. It is concluded that pentacene molecules stand up on the substrate surface, while both functionalized pentacenes lie down. A significant increase of the VOC from 0.28 to 0.83 V can be achieved upon the utilization of functionalized pentacene, owing to the modulation of molecular stacking orientation, which induced a vacuum-level shift.

  8. The value of fine needle aspiration and cytologic examination of impalpable complicated breast cysts.

    PubMed

    Tez, Selda; Dener, Cenap; Köktener, Aslý; Caydere, Muzaffer; Tez, Mesut

    2008-01-01

    The purpose of the study was to evaluate the utility of fine needle aspiration--FNA and cytologic analysis of impalpable complicated breast cysts. We rewieved the imaging findings, aspiration, cytology and biopsy results and followup imaging findings of 246 complicated cysts in 166 women retrospectively. FNA was performed in 169 out of the 246 complicated cysts. Thirtyone lesions were followed-up with US. Surgical biopsy was performed from five lesions. No malignant cells (137 cysts), insufficient cellular material (17 cysts), atypical cells (4 cysts) were seen in cytological examination of the aspirates. None of these lesions were found to represent malignancy at the time of surgical excision and during follow-up. Impalpable complicated breast cysts may be classified as probably benign and can be managed with follow-up imaging studies instead of intervention. Routine cytologic examination is unnecessary if the fluid is not bloody (Tab. 2, Ref. 18). Full Text (Free, PDF) www.bmj.sk.

  9. Polycrystalline silicon on tungsten substrates

    NASA Technical Reports Server (NTRS)

    Bevolo, A. J.; Schmidt, F. A.; Shanks, H. R.; Campisi, G. J.

    1979-01-01

    Thin films of electron-beam-vaporized silicon were deposited on fine-grained tungsten substrates under a pressure of about 1 x 10 to the -10th torr. Mass spectra from a quadrupole residual-gas analyzer were used to determine the partial pressure of 13 residual gases during each processing step. During separate silicon depositions, the atomically clean substrates were maintained at various temperatures between 400 and 780 C, and deposition rates were between 20 and 630 A min. Surface contamination and interdiffusion were monitored by in situ Auger electron spectrometry before and after cleaning, deposition, and annealing. Auger depth profiling, X-ray analysis, and SEM in the topographic and channeling modes were utilized to characterize the samples with respect to silicon-metal interface, interdiffusion, silicide formation, and grain size of silicon. The onset of silicide formation was found to occur at approximately 625 C. Above this temperature tungsten silicides were formed at a rate faster than the silicon deposition. Fine-grain silicon films were obtained at lower temperatures.

  10. Spatial Patterns of Snow Cover in North Carolina: Surface and Satellite Perspectives

    NASA Technical Reports Server (NTRS)

    Fuhrmann, Christopher M.; Hall, Dorothy K.; Perry, L. Baker; Riggs, George A.

    2010-01-01

    Snow mapping is a common practice in regions that receive large amounts of snowfall annually, have seasonally-continuous snow cover, and where snowmelt contributes significantly to the hydrologic cycle. Although higher elevations in the southern Appalachian Mountains average upwards of 100 inches of snow annually, much of the remainder of the Southeast U.S. receives comparatively little snowfall (< 10 inches). Recent snowy winters in the region have provided an opportunity to assess the fine-grained spatial distribution of snow cover and the physical processes that act to limit or improve its detection across the Southeast. In the present work, both in situ and remote sensing data are utilized to assess the spatial distribution of snow cover for a sample of recent snowfall events in North Carolina. Specifically, this work seeks to determine how well ground measurements characterize the fine-grained patterns of snow cover in relation to Moderate- Resolution Imaging Spectroradiometer (MODIS) snow cover products (in this case, the MODIS Fractional Snow Cover product).

  11. Progress in Metabolic Engineering of Saccharomyces cerevisiae

    PubMed Central

    Nevoigt, Elke

    2008-01-01

    Summary: The traditional use of the yeast Saccharomyces cerevisiae in alcoholic fermentation has, over time, resulted in substantial accumulated knowledge concerning genetics, physiology, and biochemistry as well as genetic engineering and fermentation technologies. S. cerevisiae has become a platform organism for developing metabolic engineering strategies, methods, and tools. The current review discusses the relevance of several engineering strategies, such as rational and inverse metabolic engineering, evolutionary engineering, and global transcription machinery engineering, in yeast strain improvement. It also summarizes existing tools for fine-tuning and regulating enzyme activities and thus metabolic pathways. Recent examples of yeast metabolic engineering for food, beverage, and industrial biotechnology (bioethanol and bulk and fine chemicals) follow. S. cerevisiae currently enjoys increasing popularity as a production organism in industrial (“white”) biotechnology due to its inherent tolerance of low pH values and high ethanol and inhibitor concentrations and its ability to grow anaerobically. Attention is paid to utilizing lignocellulosic biomass as a potential substrate. PMID:18772282

  12. Ash production by attrition in volcanic conduits and plumes.

    PubMed

    Jones, T J; Russell, J K

    2017-07-17

    Tephra deposits result from explosive volcanic eruption and serve as indirect probes into fragmentation processes operating in subsurface volcanic conduits. Primary magmatic fragmentation creates a population of pyroclasts through volatile-driven decompression during conduit ascent. In this study, we explore the role that secondary fragmentation, specifically attrition, has in transforming primary pyroclasts upon transport in volcanic conduits and plumes. We utilize total grain size distributions from a suite of natural and experimentally produced tephra to show that attrition is likely to occur in all explosive volcanic eruptions. Our experimental results indicate that fine ash production and surface area generation is fast (<15 min) thereby rapidly raising the fractal dimension of tephra deposits. Furthermore, a new metric, the Entropy of Information, is introduced to quantify the degree of attrition (secondary fragmentation) from grain size data. Attrition elevates fine ash production which, in turn, has consequences for eruption column stability, tephra dispersal, aggregation, volcanic lightening generation, and has concomitant effects on aviation safety and Earth's climate.

  13. Limit on the temporal variation of the fine-structure constant using atomic dysprosium.

    PubMed

    Cingöz, A; Lapierre, A; Nguyen, A-T; Leefer, N; Budker, D; Lamoreaux, S K; Torgerson, J R

    2007-01-26

    Over 8 months, we monitored transition frequencies between nearly degenerate, opposite-parity levels in two isotopes of atomic dysprosium (Dy). These frequencies are sensitive to variation of the fine-structure constant (alpha) due to relativistic corrections of opposite sign for the opposite-parity levels. In this unique system, in contrast to atomic-clock comparisons, the difference of the electronic energies of the opposite-parity levels can be monitored directly utilizing a rf electric-dipole transition between them. Our measurements show that the frequency variation of the 3.1-MHz transition in (163)Dy and the 235-MHz transition in (162)Dy are 9.0+/-6.7 Hz/yr and -0.6+/-6.5 Hz/yr, respectively. These results provide a rate of fractional variation of alpha of (-2.7+/-2.6) x 10(-15) yr(-1) (1 sigma) without assumptions on constancy of other fundamental constants, indicating absence of significant variation at the present level of sensitivity.

  14. Polymer-based adsorbent for heavy metals removal from aqueous solution

    NASA Astrophysics Data System (ADS)

    Mahmud, H. N. M. E.; Huq, A. K. O.; Yahya, R.

    2017-06-01

    A novel conducting polymer-based adsorbent, polypyrrole (PPy) fine powder has successfully been prepared as a new adsorbent and utilized in the adsorption of heavy metal ions like arsenic, zinc and cadmium ions from aqueous solution. PPy was chemically synthesized by using FeCl3.6H2O as an oxidant. The prepared PPy adsorbent was characterized by Brunauer-Emmet-Teller (BET) surface analysis, field emission scanning electron microscopy (FESEM) and attenuated total reflectance fourier transform infrared ATR-(FTIR) spectroscopy. The adsorption was conducted by varying different parameters such as, contact time, pH and adsorbent dosage. The concentrations of metal ions were measured by inductively coupled plasma mass spectroscopy (ICP-MS). The results show that PPy acts as an effective sorbent for the removal of arsenic, zinc and cadmium ions from aqueous solution. The as-prepared PPy fine powder is easy to prepare and appeared as an effective adsorbent for heavy metal ions particularly arsenic in wastewater treatment.

  15. Accelerated weathering of limestone for CO2 mitigation opportunities for the stone and cement industries

    USGS Publications Warehouse

    Langer, W.H.; Juan, C.A.S.; Rau, G.H.; Caldeira, K.

    2009-01-01

    Large amounts of limestone fines coproduced during the processing of crushed limestone may be useful in the sequestration of carbon dioxide (CO 2). Accelerated weathering of limestone (AWL) is proposed as a low-tech method to capture and sequester CO2 from fossil fuel-fired power plants and other point-sources such as cement manufacturing. AWL reactants are readily available, inexpensive, and environmentally benign. Waste CO 2 is hydrated with water to produce carbonic acid, which then reacts with and is neutralized by limestone fines, thus converting CO2 gas to dissolved calcium bicarbonate. AWL waste products can be disposed of in the ocean. Feasibility requires access to an inexpensive source of limestone and to seawater, thus limiting AWL facilities within about 10 km of the coastline. The majority of U.S. coastal power generating facilities are within economical transport distance of limestone resources. AWL presents opportunities for collaborative efforts among the crushed stone industry, electrical utilities, cement manufactures, and research scientists.

  16. Nano-textured high sensitivity ion sensitive field effect transistors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hajmirzaheydarali, M.; Sadeghipari, M.; Akbari, M.

    2016-02-07

    Nano-textured gate engineered ion sensitive field effect transistors (ISFETs), suitable for high sensitivity pH sensors, have been realized. Utilizing a mask-less deep reactive ion etching results in ultra-fine poly-Si features on the gate of ISFET devices where spacing of the order of 10 nm and less is achieved. Incorporation of these nano-sized features on the gate is responsible for high sensitivities up to 400 mV/pH in contrast to conventional planar structures. The fabrication process for this transistor is inexpensive, and it is fully compatible with standard complementary metal oxide semiconductor fabrication procedure. A theoretical modeling has also been presented to predict themore » extension of the diffuse layer into the electrolyte solution for highly featured structures and to correlate this extension with the high sensitivity of the device. The observed ultra-fine features by means of scanning electron microscopy and transmission electron microscopy tools corroborate the theoretical prediction.« less

  17. Particulate Respirators Functionalized with Silver Nanoparticles Showed Excellent Real-Time Antimicrobial Effects against Pathogens.

    PubMed

    Zheng, Clark Renjun; Li, Shuai; Ye, Chengsong; Li, Xinyang; Zhang, Chiqian; Yu, Xin

    2016-07-05

    Particulate respirators designed to filtrate fine particulate matters usually do not possess antimicrobial functions. The current study aimed to functionalize particulate respirators with silver nanoparticles (nanosilver or AgNPs), which have excellent antimicrobial activities, utilizing a straightforward and effective method. We first enhanced the nanosilver-coating ability of nonwoven fabrics from a particulate respirator through surface modification by sodium oleate. The surfactant treatment significantly improved the fabrics' water wet preference where the static water contact angles reduced from 122° to 56°. Both macroscopic agar-plate tests and microscopic scanning electron microscope (SEM) characterization revealed that nanosilver functionalized fabrics could effectively inhibit the growth of two model bacterial strains (i.e., Staphylococcus aureus and Pseudomonas aeruginosa). The coating of silver nanoparticles would not affect the main function of particulate respirators (i.e., filtration of fine air-borne particles). Nanosilver coated particulate respirators with excellent antimicrobial activities can provide real-time protection to people in regions with severe air pollution against air-borne pathogens.

  18. Spiral drawing performance as an indicator of fine motor function in people with multiple sclerosis.

    PubMed

    Longstaff, M G; Heath, R A

    2006-10-01

    This study investigated spiral drawing performance as an indicator of fine motor function, as well as to gain insight into adaptive movement strategies used by people with multiple sclerosis (MS). Seven people with MS, nine younger controls (mean age of 20) and eight older controls (mean age of 40) drew spirals on a graphics tablet at a comfortable speed and size. Spirography (i.e., a subjective visual assessment of the static trace) revealed indications of reduced control of the pen for people with MS. Analysis of the movements showed that people with MS tended to draw the spirals slower and with less pen pressure than controls. All groups increased their speed and pressure along with spiral size, but this increase was much steeper for the controls. MS participants drew spirals with more variability around an ideal trajectory, highlighting fine motor control degradation. MS patients tended to use a smaller scaling ratio, resulting in smaller spirals for a given number of revolutions. The younger and older control groups drew the spirals in a similar manner, and age was not a significant factor in any of the analyses. It is argued that the relatively lower pressure used, and slower, smaller movements (particularly during the more difficult outer sections of the spiral) are in part an adaptive strategy used to reduce movement variability. These results demonstrate the utility of the analysis of spiral movements as an objective technique for assessing motor control degradation, which can compliment the subjective rating based on the static pen trace. As such, it can provide further insight into the biomechanical strategies used when performing fine movements.

  19. Evaluation of an enhanced gravity-based fine-coal circuit for high-sulfur coal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mohanty, M.K.; Samal, A.R.; Palit, A.

    One of the main objectives of this study was to evaluate a fine-coal cleaning circuit using an enhanced gravity separator specifically for a high sulfur coal application. The evaluation not only included testing of individual unit operations used for fine-coal classification, cleaning and dewatering, but also included testing of the complete circuit simultaneously. At a scale of nearly 2 t/h, two alternative circuits were evaluated to clean a minus 0.6-mm coal stream utilizing a 150-mm-diameter classifying cyclone, a linear screen having a projected surface area of 0.5 m{sup 2}, an enhanced gravity separator having a bowl diameter of 250 mmmore » and a screen-bowl centrifuge having a bowl diameter of 500 mm. The cleaning and dewatering components of both circuits were the same; however, one circuit used a classifying cyclone whereas the other used a linear screen as the classification device. An industrial size coal spiral was used to clean the 2- x 0.6-mm coal size fraction for each circuit to estimate the performance of a complete fine-coal circuit cleaning a minus 2-mm particle size coal stream. The 'linear screen + enhanced gravity separator + screen-bowl circuit' provided superior sulfur and ash-cleaning performance to the alternative circuit that used a classifying cyclone in place of the linear screen. Based on these test data, it was estimated that the use of the recommended circuit to treat 50 t/h of minus 2-mm size coal having feed ash and sulfur contents of 33.9% and 3.28%, respectively, may produce nearly 28.3 t/h of clean coal with product ash and sulfur contents of 9.15% and 1.61 %, respectively.« less

  20. Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants

    PubMed Central

    Gala, Manish; Abecasis, Goncalo; Bezieau, Stephane; Brenner, Hermann; Butterbach, Katja; Caan, Bette J.; Carlson, Christopher S.; Casey, Graham; Chang-Claude, Jenny; Conti, David V.; Curtis, Keith R.; Duggan, David; Gallinger, Steven; Haile, Robert W.; Harrison, Tabitha A.; Hayes, Richard B.; Hoffmeister, Michael; Hopper, John L.; Hudson, Thomas J.; Jenkins, Mark A.; Küry, Sébastien; Le Marchand, Loic; Leal, Suzanne M.; Newcomb, Polly A.; Nickerson, Deborah A.; Potter, John D.; Schoen, Robert E.; Schumacher, Fredrick R.; Seminara, Daniela; Slattery, Martha L.; Hsu, Li; Chan, Andrew T.; White, Emily; Berndt, Sonja I.; Peters, Ulrike

    2016-01-01

    Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) associated with colorectal cancer risk. These SNPs may tag correlated variants with biological importance. Fine-mapping around GWAS loci can facilitate detection of functional candidates and additional independent risk variants. We analyzed 11,900 cases and 14,311 controls in the Genetics and Epidemiology of Colorectal Cancer Consortium and the Colon Cancer Family Registry. To fine-map genomic regions containing all known common risk variants, we imputed high-density genetic data from the 1000 Genomes Project. We tested single-variant associations with colorectal tumor risk for all variants spanning genomic regions 250-kb upstream or downstream of 31 GWAS-identified SNPs (index SNPs). We queried the University of California, Santa Cruz Genome Browser to examine evidence for biological function. Index SNPs did not show the strongest association signals with colorectal tumor risk in their respective genomic regions. Bioinformatics analysis of SNPs showing smaller P-values in each region revealed 21 functional candidates in 12 loci (5q31.1, 8q24, 11q13.4, 11q23, 12p13.32, 12q24.21, 14q22.2, 15q13, 18q21, 19q13.1, 20p12.3, and 20q13.33). We did not observe evidence of additional independent association signals in GWAS-identified regions. Our results support the utility of integrating data from comprehensive fine-mapping with expanding publicly available genomic databases to help clarify GWAS associations and identify functional candidates that warrant more onerous laboratory follow-up. Such efforts may aid the eventual discovery of disease-causing variant(s). PMID:27379672

  1. Cost-effectiveness analysis of repeat fine-needle aspiration for thyroid biopsies read as atypia of undetermined significance.

    PubMed

    Heller, Michael; Zanocco, Kyle; Zydowicz, Sara; Elaraj, Dina; Nayar, Ritu; Sturgeon, Cord

    2012-09-01

    The 2007 National Cancer Institute (NCI) conference on Thyroid Fine-Needle Aspiration (FNA) introduced the category atypia of undetermined significance (AUS) or follicular lesion of undetermined significance (FLUS). Repeat FNA in 3 to 6 months was recommended for low-risk patients. Compliance with these recommendations has been suboptimal. We hypothesized that repeat FNA would be more effective than diagnostic lobectomy, with decreased costs and improved rates of cancer detection. Cost-effectiveness analysis was performed in which we compared diagnostic lobectomy with repeat FNA. A Markov model was developed. Outcomes and probabilities were identified from literature review. Third-party payer costs were estimated in 2010 US dollars. Outcomes were weighted by use of the quality-of-life utility factors, yielding quality-adjusted life years (QALYs). Monte Carlo simulation and sensitivity analysis were used to examine the uncertainty of probability, cost, and utility estimates. The diagnostic lobectomy strategy cost $8,057 and produced 23.99 QALYs. Repeat FNA cost $2,462 and produced 24.05 QALYs. Repeat FNA was dominant until the cost of FNA increased to $6,091. Dominance of the repeat FNA strategy was not sensitive to the cost of operation or the complication rate. The NCI recommendations for repeat FNA regarding follow-up of AUS/FLUS results are cost-effective. Improving compliance with these guidelines should lead to less overall costs, greater quality of life, and fewer unnecessary operations. Copyright © 2012 Mosby, Inc. All rights reserved.

  2. Rapid magnetic microfluidic mixer utilizing AC electromagnetic field.

    PubMed

    Wen, Chih-Yung; Yeh, Cheng-Peng; Tsai, Chien-Hsiung; Fu, Lung-Ming

    2009-12-01

    This paper presents a novel simple micromixer based on stable water suspensions of magnetic nanoparticles (i.e. ferrofluids). The micromixer chip is built using standard microfabrication and simple soft lithography, and the design can be incorporated as a subsystem into any chemical microreactor or a miniaturized biological sensor. An electromagnet driven by an AC power source is used to induce transient interactive flows between a ferrofluid and Rhodamine B. The alternative magnetic field causes the ferrofluid to expand significantly and uniformly toward Rhodamine B, associated with a great number of extremely fine fingering structures on the interface in the upstream and downstream regions of the microchannel. These pronounced fingering patterns, which have not been observed by other active mixing methods utilizing only magnetic force, increase the mixing interfacial length dramatically. Along with the dominant diffusion effects occurring around the circumferential regions of the fine finger structures, the mixing efficiency increases significantly. The miscible fingering instabilities are observed and applied in the microfluidics for the first time. This work is carried with a view to developing functionalized ferrofluids that can be used as sensitive pathogen detectors and the present experimental results demonstrate that the proposed micromixer has excellent mixing capabilities. The mixing efficiency can be as high as 95% within 2.0 s and a distance of 3.0 mm from the inlet of the mixing channel, when the applied peak magnetic field is higher than 29.2 Oe and frequency ranges from 45 to 300 Hz.

  3. Evaluation of biodiesel’s impact on real-world occupational and environmental particulate matter exposures at a municipal facility in Keene, NH

    PubMed Central

    Thelen, Brett Amy; Ingalls, Jaime Kathryn; Treadwell, Melinda Dawn

    2016-01-01

    Many organizations are interested in biodiesel as a renewable, domestic energy source for use in transportation and heavy-duty equipment. Although numerous biodiesel emission studies exist, biodiesel exposure studies are nearly absent from the literature. This study compared the impact of petroleum diesel fuel and a B20 blend (20% soy-based biodiesel/80% petroleum diesel) on occupational and environmental exposures at a rural municipal facility in Keene, NH. For each fuel type, we measured concentrations of fine particulate matter (PM2.5), elemental carbon (EC), and organic carbon (OC) at multiple locations (in-cabin, work area, and near-field) at a materials recovery facility utilizing non-road equipment. B20 fuel use resulted in significant reductions in PM2.5 mass (56–76%), reductions in EC (5–29%), and increases in OC (294–467%). Concentrations of PM2.5 measured during petroleum diesel use were up to four times higher than PM2.5 concentrations during B20 use. Further analysis of the EC and OC fractions of total carbon also indicated substantial differences between fuels. Our results demonstrate that biodiesel blends significantly reduced PM2.5 exposure compared to petroleum diesel fuel in a workplace utilizing non-road construction-type equipment. While this suggests that biodiesel may reduce health risks associated with exposure to fine particulate matter mass, more exposure research is needed to better understand biodiesel-related changes in particulate matter composition and other exposure metrics.

  4. Summary of the Third AIAA CFD Drag Prediction Workshop

    NASA Technical Reports Server (NTRS)

    Vassberg, John C.; Tinoco, Edward N.; Mani, Mori; Brodersen, Olaf P.; Eisfeld, Bernhard; Wahls, Richard A.; Morrison, Joseph H.; Zickuhr, Tom; Laflin, Kelly R.; Mavriplis, DImitri J.

    2007-01-01

    The workshop focused on the prediction of both absolute and differential drag levels for wing-body and wing-al;one configurations of that are representative of transonic transport aircraft. The baseline DLR-F6 wing-body geometry, previously utilized in DPW-II, is also augmented with a side-body fairing to help reduce the complexity of the flow physics in the wing-body juncture region. In addition, two new wing-alone geometries have been developed for the DPW-II. Numerical calculations are performed using industry-relevant test cases that include lift-specific and fixed-alpha flight conditions, as well as full drag polars. Drag, lift, and pitching moment predictions from previous Reynolds-Averaged Navier-Stokes computational fluid Dynamics Methods are presented, focused on fully-turbulent flows. Solutions are performed on structured, unstructured, and hybrid grid systems. The structured grid sets include point-matched multi-block meshes and over-set grid systems. The unstructured and hybrid grid sets are comprised of tetrahedral, pyramid, and prismatic elements. Effort was made to provide a high-quality and parametrically consistent family of grids for each grid type about each configuration under study. The wing-body families are comprised of a coarse, medium, and fine grid, while the wing-alone families also include an extra-fine mesh. These mesh sequences are utilized to help determine how the provided flow solutions fair with respect to asymptotic grid convergence, and are used to estimate an absolute drag of each configuration.

  5. Use of wastes derived from earthquakes for the production of concrete masonry partition wall blocks.

    PubMed

    Xiao, Zhao; Ling, Tung-Chai; Kou, Shi-Cong; Wang, Qingyuan; Poon, Chi-Sun

    2011-08-01

    Utilization of construction and demolition (C&D) wastes as recycled aggregates in the production of concrete and concrete products have attracted much attention in recent years. However, the presence of large quantities of crushed clay brick in some the C&D waste streams (e.g. waste derived collapsed masonry buildings after an earthquake) renders the recycled aggregates unsuitable for high grade use. One possibility is to make use of the low grade recycled aggregates for concrete block production. In this paper, we report the results of a comprehensive study to assess the feasibility of using crushed clay brick as coarse and fine aggregates in concrete masonry block production. The effects of the content of crushed coarse and fine clay brick aggregates (CBA) on the mechanical properties of non-structural concrete block were quantified. From the experimental test results, it was observed that incorporating the crushed clay brick aggregates had a significant influence on the properties of blocks. The hardened density and drying shrinkage of the block specimens decreased with an increase in CBA content. The use of CBA increased the water absorption of block specimens. The results suggested that the amount of crushed clay brick to be used in concrete masonry blocks should be controlled at less than 25% (coarse aggregate) and within 50-75% for fine aggregates. Copyright © 2011 Elsevier Ltd. All rights reserved.

  6. Assessment of Pb-slag, MSWI bottom ash and boiler and fly ash for using as a fine aggregate in cement mortar.

    PubMed

    Saikia, Nabajyoti; Cornelis, Geert; Mertens, Gilles; Elsen, Jan; Van Balen, Koenraad; Van Gerven, Tom; Vandecasteele, Carlo

    2008-06-15

    Three types of wastes, metallurgical slag from Pb production (SLG), the sand-sized (0.1-2 mm) fraction of MSWI bottom ash from a grate furnace (SF), and boiler and fly ash from a fluidised bed incinerator (BFA), were characterized and used to replace the fine aggregate during preparation of cement mortar. The chemical and mineralogical behaviour of these wastes along with the reactivities of the wastes with lime and the hydration behaviour of ordinary Portland cement paste with and without these wastes added were evaluated by various chemical and instrumental techniques. The compressive strengths of the cement mortars containing waste as a partial substitution of fine aggregates were also assessed. Finally, leaching studies of the wastes and waste containing cement mortars were conducted. SLG addition does not show any adverse affect during the hydration of cement, or on the compressive strengths behaviours of mortars. Formation of expansive products like ettringite, aluminium hydroxide and H2 gas due to the reaction of some constituents of BFA and SF with alkali creates some cracks in the paste as well as in the cement mortars, which lower the compressive strength of the cement mortars. However, utilization of all materials in cement-based application significantly improves the leaching behaviour of the majority of the toxic elements compared to the waste as such.

  7. Stability of the Medial Olivocochlear Reflex as Measured by Distortion Product Otoacoustic Emissions

    PubMed Central

    Abdala, Carolina

    2015-01-01

    Purpose The purpose of this study was to assess the repeatability of a fine-resolution, distortion product otoacoustic emission (DPOAE)–based assay of the medial olivocochlear (MOC) reflex in normal-hearing adults. Method Data were collected during 36 test sessions from 4 normal-hearing adults to assess short-term stability and 5 normal-hearing adults to assess long-term stability. DPOAE level and phase measurements were recorded with and without contralateral acoustic stimulation. MOC reflex indices were computed by (a) noting contralateral acoustic stimulation-induced changes in DPOAE level (both absolute and normalized) at fine-structure peaks, (b) recording the effect as a vector difference, and (c) separating DPOAE components and considering a component-specific metric. Results Analyses indicated good repeatability of all indices of the MOC reflex in most frequency ranges. Short- and long-term repeatability were generally comparable. Indices normalized to a subject's own baseline fared best, showing strong short- and long-term stability across all frequency intervals. Conclusions These results suggest that fine-resolution DPOAE-based measures of the MOC reflex measured at strategic frequencies are stable, and natural variance from day-to-day or week-to-week durations is small enough to detect between-group differences and possibly to monitor intervention-related success. However, this is an empirical question that must be directly tested to confirm its utility. PMID:25320951

  8. Hope for the Forests? Habitat Resiliency Illustrated in the Face of Climate Change Using Fine-Scale Modeling

    NASA Astrophysics Data System (ADS)

    Flint, L. E.; Flint, A. L.; Weiss, S. B.; Micheli, E. R.

    2010-12-01

    In the face of rapid climate change, fine-scale predictions of landscape change are of extreme interest to land managers that endeavor to develop long term adaptive strategies for maintaining biodiversity and ecosystem services. Global climate model (GCM) outputs, which generally focus on estimated increases in air temperature, are increasingly applied to species habitat distribution models. For sensitive species subject to climate change, habitat models predict significant migration (either northward or towards higher elevations), or complete extinction. Current studies typically rely on large spatial scale GCM projections (> 10 km) of changes in precipitation and air temperature: at this scale, these models necessarily neglect subtleties of topographic shading, geomorphic expression of the landscape, and fine-scale differences in soil properties - data that is readily available at meaningful local scales. Recent advances in modeling take advantage of available soils, geology, and topographic data to construct watershed-scale scenarios using GCM inputs and result in improved correlations of vegetation distribution with temperature. For this study, future climate projections were downscaled to 270-m and applied to a physically-based hydrologic model to calculate future changes in recharge, runoff, and climatic water deficit (CWD) for basins draining into the northern San Francisco Bay. CWD was analyzed for mapped vegetation types to evaluate the range of CWD for historic time periods in comparison to future time periods. For several forest communities (including blue oak woodlands, montane hardwoods, douglas-fir, and coast redwood) existing landscape area exhibiting suitable CWD diminishes by up 80 percent in the next century, with a trend towards increased CWD throughout the region. However, no forest community loses all suitable habitat, with islands of potential habitat primarily remaining on north facing slopes and deeper soils. Creation of new suitable habitat is also predicted throughout the region. Results have direct application to management issues of habitat connectivity, forest land protection and acquisition, and active management solutions such as transplanting or assisted migration. Although this analysis considers only one driver of forest habitat distribution, consideration of hydrologic derivatives at a fine scale explains current forest community distributions and provides a far more informed perspective on potential future forest distributions. Results demonstrate the utility of fine-scale modeling and provide landscape managers and conservation agencies valuable management tools in fine-scale future forest scenarios and a framework for evaluating forest resiliency in a changing climate.

  9. Sea water rope batteries

    NASA Astrophysics Data System (ADS)

    Walsh, M.

    1984-05-01

    This research demonstrated the feasibility of supplying approximately 1 watt of electrical power for one year on the sea bed with a novel battery, the rope battery. The proposed battery would look very much like a small diameter wire rope, possibly hundreds of feet long. This unusual shape permits the rope battery to take full advantage of the vastness of the ocean floor and permits at great pressure the steady diffusion of reaction products away from the battery itself. A sea water battery is described consisting of an inner bundle of coated wires which slowly corrode and an outer layer of fine wires which simultaneously provides strength, armor and surface area for slow hydrogen evolution. Two variations are examined. The fuse utilizes magnesium wires and burns slowly from the end. The rope utilizes lithium-zinc alloys and is slowly consumed along its entire length.

  10. Utilization of ultrasonic atomization for dust control in underground mining

    NASA Astrophysics Data System (ADS)

    Okawa, Hirokazu; Nishi, Kentaro; Kawamura, Youhei; Kato, Takahiro; Sugawara, Katsuyasu

    2017-07-01

    This study examined dust suppression using water particles generated by ultrasonic atomization (2.4 MHz) at low temperature (10 °C). Green tuff (4 µm), green tuff (6 µm), kaolin, and silica were used as dust samples. Even though ultrasonic atomization makes fine water particles, raising relative air humidity immediately was difficult at low temperature. However, remaining water particles that did not change to water vapor contributed to suppression of dust dispersion. Additionally, the effect of water vapor amount (absolute humidity) and water particles generated by ultrasonic atomization on the amount of dust dispersion was investigated using experimental data at temperatures of 10, 20, and 30 °C. Utilization of ultrasound atomization at low temperature has the advantages of low humidity increments in the working space and water particles remaining stable even with low relative air humidity.

  11. Recent advances in microbial production of mannitol: utilization of low-cost substrates, strain development and regulation strategies.

    PubMed

    Zhang, Min; Gu, Lei; Cheng, Chao; Ma, Jiangfeng; Xin, Fengxue; Liu, Junli; Wu, Hao; Jiang, Min

    2018-02-26

    Mannitol has been widely used in fine chemicals, pharmaceutical industries, as well as functional foods due to its excellent characteristics, such as antioxidant protecting, regulation of osmotic pressure and non-metabolizable feature. Mannitol can be naturally produced by microorganisms. Compared with chemical manufacturing, microbial production of mannitol provides high yield and convenience in products separation; however the fermentative process has not been widely adopted yet. A major obstacle to microbial production of mannitol under industrial-scale lies in the low economical efficiency, owing to the high cost of fermentation medium, leakage of fructose, low mannitol productivity. In this review, recent advances in improving the economical efficiency of microbial production of mannitol were reviewed, including utilization of low-cost substrates, strain development for high mannitol yield and process regulation strategies for high productivity.

  12. Test problems for inviscid transonic flow

    NASA Technical Reports Server (NTRS)

    Carlson, L. A.

    1979-01-01

    Solving of test problems with the TRANDES program is discussed. This method utilizes the full, inviscid, perturbation potential flow equation in a Cartesian grid system that is stretched to infinity. This equation is represented by a nonconservative system of finite difference equations that includes at supersonic points a rotated difference scheme and is solved by column relaxation. The solution usually starts from a zero perturbation potential on a very coarse grid (typically 13 by 7) followed by several grid halvings until a final solution is obtained on a fine grid (97 by 49).

  13. Controlled crack growth specimen for brittle systems

    NASA Technical Reports Server (NTRS)

    Calomino, Anthony M.; Brewer, David N.

    1990-01-01

    A pure Mode 1 fracture specimen and test procedure has been developed which provides extended, stable, through-thickness crack growth in ceramics and other brittle, nonmetallic materials. Fixed displacement loading, applied at the crack mouth, promotes stable crack extension by reducing the stored elastic strain energy. Extremely fine control of applied displacements is achieved by utilizing the Poisson's expansion of a compressively loaded cylindrical pin. Stable cracks were successfully grown in soda-lime glass and monolithic Al2O3 for lengths in excess of 20 mm without uncontrollable catastrophic failure.

  14. Controlled crack growth specimen for brittle systems

    NASA Technical Reports Server (NTRS)

    Calomino, Anthony M.; Brewer, David N.

    1992-01-01

    A pure Mode 1 fracture specimen and test procedure has been developed which provides extended, stable, through-thickness crack growth in ceramics and other brittle, nonmetallic materials. Fixed displacement loading, applied at the crack mouth, promotes stable crack extension by reducing the stored elastic strain energy. Extremely fine control of applied displacements is achieved by utilizing the Poisson's expansion of a compressively loaded cylindrical pin. Stable cracks were successfully grown in soda-lime glass and monolithic Al2O3 for lengths in excess of 2O mm without uncontrollable catastrophic failure.

  15. Unmanned Aircraft Systems For CryoSat-2 Validation

    NASA Astrophysics Data System (ADS)

    Crocker, Roger Ian; Maslanik, James A.

    2011-02-01

    A suite of sensors has been assembled to map surface elevation with fine-resolution from small unmanned aircraft systems (UAS). The sensor package consists of a light detecting and ranging (LIDAR) instrument, an inertial measurement unit (IMU), a GPS module, and digital still and video cameras. It has been utilized to map ice sheet topography in Greenland and to measure sea ice freeboard and roughness in Fram Strait. Data collected during these campaigns illustrate its potential to compliment ongoing CryoSat-2 (CS-2) calibration and validation efforts.

  16. Rapid and precise scanning helium ion microscope milling of solid-state nanopores for biomolecule detection.

    PubMed

    Yang, Jijin; Ferranti, David C; Stern, Lewis A; Sanford, Colin A; Huang, Jason; Ren, Zheng; Qin, Lu-Chang; Hall, Adam R

    2011-07-15

    We report the formation of solid-state nanopores using a scanning helium ion microscope. The fabrication process offers the advantage of high sample throughput along with fine control over nanopore dimensions, producing single pores with diameters below 4 nm. Electronic noise associated with ion transport through the resultant pores is found to be comparable with levels measured on devices made with the established technique of transmission electron microscope milling. We demonstrate the utility of our nanopores for biomolecular analysis by measuring the passage of double-strand DNA.

  17. Demeter-W

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2017-09-27

    Demeter-W, an open-access software written in Python, consists of extensible module packages. It is developed with statistical downscaling algorithms, to spatially and temporally downscale water demand data into finer scale. The spatial resolution will be downscaled from region/basin scale to grid (0.5 geographic degree) scale and the temporal resolution will be downscaled from year to month. For better understanding of the driving forces and patterns for global water withdrawal, the researchers is able to utilize Demeter-W to reconstruct the data sets to examine the issues related to water withdrawals at fine spatial and temporal scales.

  18. Chromatin versus pathogens: the function of epigenetics in plant immunity

    PubMed Central

    Ding, Bo; Wang, Guo-Liang

    2015-01-01

    To defend against pathogens, plants have developed a sophisticated innate immunity that includes effector recognition, signal transduction, and rapid defense responses. Recent evidence has demonstrated that plants utilize the epigenetic control of gene expression to fine-tune their defense when challenged by pathogens. In this review, we highlight the current understanding of the molecular mechanisms of histone modifications (i.e., methylation, acetylation, and ubiquitination) and chromatin remodeling that contribute to plant immunity against pathogens. Functions of key histone-modifying and chromatin remodeling enzymes are discussed. PMID:26388882

  19. Self regulating formulations for safe hydrogen gettering

    DOEpatents

    Shepodd, Timothy Jon

    2002-01-01

    A method and composition are disclosed for preventing uncontrolled exothermic reaction in the presence of a catalyst. A catalyst deployed as a finely divided powder which is attached to the surface of a low melting point wax or wax-like material which is utilized as a carrier for the catalyst. During operation should the catalyst overheat due to uncontrolled conditions brought about by a run-away reaction the heat of reaction melts the low melting point wax which would itself wet the surface of the catalyst and prevent further catalysis.

  20. Overcoming the “Oxidant Problem”: Strategies to Use O2 as the Oxidant in Organometallic C–H Oxidation Reactions Catalyzed by Pd (and Cu)

    PubMed Central

    Campbell, Alison N.; Stahl, Shannon S.

    2012-01-01

    Oxidation reactions are key transformations in organic chemistry because they can increase chemical complexity and incorporate heteroatom substituents into carbon-based molecules. This principle is manifested in the conversion of petrochemical feedstocks into commodity chemicals and in the synthesis of fine chemicals, pharmaceuticals, and other complex organic molecules. The utility and function of such molecules correlate directly with the presence and specific placement of oxygen and nitrogen heteroatoms and other functional groups within the molecules. PMID:22263575

  1. Application Characterization at Scale: Lessons learned from developing a distributed Open Community Runtime system for High Performance Computing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Landwehr, Joshua B.; Suetterlein, Joshua D.; Marquez, Andres

    2016-05-16

    Since 2012, the U.S. Department of Energy’s X-Stack program has been developing solutions including runtime systems, programming models, languages, compilers, and tools for the Exascale system software to address crucial performance and power requirements. Fine grain programming models and runtime systems show a great potential to efficiently utilize the underlying hardware. Thus, they are essential to many X-Stack efforts. An abundant amount of small tasks can better utilize the vast parallelism available on current and future machines. Moreover, finer tasks can recover faster and adapt better, due to a decrease in state and control. Nevertheless, current applications have been writtenmore » to exploit old paradigms (such as Communicating Sequential Processor and Bulk Synchronous Parallel processing). To fully utilize the advantages of these new systems, applications need to be adapted to these new paradigms. As part of the applications’ porting process, in-depth characterization studies, focused on both application characteristics and runtime features, need to take place to fully understand the application performance bottlenecks and how to resolve them. This paper presents a characterization study for a novel high performance runtime system, called the Open Community Runtime, using key HPC kernels as its vehicle. This study has the following contributions: one of the first high performance, fine grain, distributed memory runtime system implementing the OCR standard (version 0.99a); and a characterization study of key HPC kernels in terms of runtime primitives running on both intra and inter node environments. Running on a general purpose cluster, we have found up to 1635x relative speed-up for a parallel tiled Cholesky Kernels on 128 nodes with 16 cores each and a 1864x relative speed-up for a parallel tiled Smith-Waterman kernel on 128 nodes with 30 cores.« less

  2. An 11-year global gridded aerosol optical thickness reanalysis (v1.0) for atmospheric and climate sciences

    NASA Astrophysics Data System (ADS)

    Lynch, Peng; Reid, Jeffrey S.; Westphal, Douglas L.; Zhang, Jianglong; Hogan, Timothy F.; Hyer, Edward J.; Curtis, Cynthia A.; Hegg, Dean A.; Shi, Yingxi; Campbell, James R.; Rubin, Juli I.; Sessions, Walter R.; Turk, F. Joseph; Walker, Annette L.

    2016-04-01

    While stand alone satellite and model aerosol products see wide utilization, there is a significant need in numerous atmospheric and climate applications for a fused product on a regular grid. Aerosol data assimilation is an operational reality at numerous centers, and like meteorological reanalyses, aerosol reanalyses will see significant use in the near future. Here we present a standardized 2003-2013 global 1 × 1° and 6-hourly modal aerosol optical thickness (AOT) reanalysis product. This data set can be applied to basic and applied Earth system science studies of significant aerosol events, aerosol impacts on numerical weather prediction, and electro-optical propagation and sensor performance, among other uses. This paper describes the science of how to develop and score an aerosol reanalysis product. This reanalysis utilizes a modified Navy Aerosol Analysis and Prediction System (NAAPS) at its core and assimilates quality controlled retrievals of AOT from the Moderate Resolution Imaging Spectroradiometer (MODIS) on Terra and Aqua and the Multi-angle Imaging SpectroRadiometer (MISR) on Terra. The aerosol source functions, including dust and smoke, were regionally tuned to obtain the best match between the model fine- and coarse-mode AOTs and the Aerosol Robotic Network (AERONET) AOTs. Other model processes, including deposition, were tuned to minimize the AOT difference between the model and satellite AOT. Aerosol wet deposition in the tropics is driven with satellite-retrieved precipitation, rather than the model field. The final reanalyzed fine- and coarse-mode AOT at 550 nm is shown to have good agreement with AERONET observations, with global mean root mean square error around 0.1 for both fine- and coarse-mode AOTs. This paper includes a discussion of issues particular to aerosol reanalyses that make them distinct from standard meteorological reanalyses, considerations for extending such a reanalysis outside of the NASA A-Train era, and examples of how the aerosol reanalysis can be applied or fused with other model or remote sensing products. Finally, the reanalysis is evaluated in comparison with other available studies of aerosol trends, and the implications of this comparison are discussed.

  3. Development studies towards an 11-year global gridded aerosol optical thickness reanalysis for climate and applied applications

    NASA Astrophysics Data System (ADS)

    Lynch, P.; Reid, J. S.; Westphal, D. L.; Zhang, J.; Hogan, T. F.; Hyer, E. J.; Curtis, C. A.; Hegg, D. A.; Shi, Y.; Campbell, J. R.; Rubin, J. I.; Sessions, W. R.; Turk, F. J.; Walker, A. L.

    2015-12-01

    While standalone satellite and model aerosol products see wide utilization, there is a significant need in numerous climate and applied applications for a fused product on a regular grid. Aerosol data assimilation is an operational reality at numerous centers, and like meteorological reanalyses, aerosol reanalyses will see significant use in the near future. Here we present a standardized 2003-2013 global 1° × 1° and 6 hourly modal aerosol optical thickness (AOT) reanalysis product. This dataset can be applied to basic and applied earth system science studies of significant aerosol events, aerosol impacts on numerical weather prediction, and electro-optical propagation and sensor performance, among other uses. This paper describes the science of how to develop and score an aerosol reanalysis product. This reanalysis utilizes a modified Navy Aerosol Analysis and Prediction System (NAAPS) at its core and assimilates quality controlled retrievals of AOT from the Moderate Resolution Imaging Spectroradiometer (MODIS) on Terra and Aqua and the Multi-angle Imaging SpectroRadiometer (MISR) on Terra. The aerosol source functions, including dust and smoke, were regionally tuned to obtain the best match between the model fine and coarse mode AOTs and the Aerosol Robotic Network (AERONET) AOTs. Other model processes, including deposition, were tuned to minimize the AOT difference between the model and satellite AOT. Aerosol wet deposition in the tropics is driven with satellite retrieved precipitation, rather than the model field. The final reanalyzed fine and coarse mode AOT at 550 nm is shown to have good agreement with AERONET observations, with global mean root mean square error around 0.1 for both fine and coarse mode AOTs. This paper includes a discussion of issues particular to aerosol reanalyses that make them distinct from standard meteorological reanalyses, considerations for extending such a reanalysis outside of the NASA A-Train era, and examples of how the aerosol reanalysis can be applied or fused with other model or remote sensing products. Finally, the reanalysis is evaluated in comparison with other available studies of aerosol trends, and the implications of this comparison are discussed.

  4. Tailoring microstructure of Mg–Zn–Y alloys with quasicrystal and related phases for high mechanical strength

    PubMed Central

    Singh, Alok

    2014-01-01

    The occurrence of a stable icosahedral (i-) phase, which is quasicrystalline with an icosahedral (fivefold) symmetry, on the equilibrium phase diagram of Mg–Zn–RE (RE = Y, Gd, Tb, Dy, Ho or Er) alloys opened up an interesting possibility of developing a new series of magnesium alloys for structural applications. Alloys based on the i-phase have been studied for the past 14 years. Ultra-high strengths combined with good ductility have been shown. Here we show two strategies for tailoring microstructures for very high strengths in Mg–Zn–Y alloys. One of them involves strengthening by a fine distribution of rod-like precipitates, where the matrix grain size is not critical. The alloy is solutionized at a high temperature of 480 °C to dissolve a large part of the i-phase, followed by a high temperature extrusion (∼430 °C) and a low temperature ageing to reprecipitate phases with fine size distribution. At first, phase transformations involved in this procedure are described. The closeness of the structure of the precipitates to the i-phase is brought out. By this procedure, tensile yield strengths of over 370 MPa are obtained in grain sizes of 20 μm. In another strategy, the alloys are chill cast and then extruded at low temperatures of about 250 °C. Ultra-fine grains are produced by enhanced recrystallization due to presence of the i-phase. At the same time nano-sized precipitates are precipitated dynamically during extrusion from the supersaturated matrix. Ultra-high tensile strengths of up to 400 MPa are obtained in combination with ductility of 12 to 16%. Analysis of the microstructure shows that strengthening by the i-phase occurs by enhanced recrystallization during extrusion. It produces ultra-fine grain sizes to give very high strengths, and moderate texture for good ductility. Fine distribution of the i-phase and precipitates contribute to strengthening and provide microstructre stability. Ultra-high strength over a very wide range of grain sizes is thus demonstrated, by utilizing different strengthening effects. PMID:27877701

  5. Formulation Optimization of Hot Melt Extruded Abuse Deterrent Pellet Dosage Form Utilizing Design of Experiments (DOE)

    PubMed Central

    Maddineni, Sindhuri; Battu, Sunil Kumar; Morott, Joe; Majumdar, Soumyajit; Repka, Michael A.

    2014-01-01

    The objective of the present study was to develop techniques for an abuse-deterrent (AD) platform utilizing hot melt extrusion (HME) process. Formulation optimization was accomplished by utilizing Box-Behnken design of experiments to determine the effect of the three formulation factors: PolyOx™ WSR301, Benecel™ K15M, and Carbopol 71G; each of which was studied at three levels on TR attributes of the produced melt extruded pellets. A response surface methodology was utilized to identify the optimized formulation. Lidocaine Hydrochloride was used as a model drug, and suitable formulation ingredients were employed as carrier matrices and processing aids. All of the formulations were evaluated for the TR attributes such as particle size post-milling, gelling, percentage of drug extraction in water and alcohol. All of the DOE formulations demonstrated sufficient hardness and elasticity, and could not be reduced into fine particles (<150µm), which is a desirable feature to prevent snorting. In addition, all of the formulations exhibited good gelling tendency in water with minimal extraction of drug in the aqueous medium. Moreover, Benecel™ K15M in combination with PolyOx™ WSR301 could be utilized to produce pellets with TR potential. HME has been demonstrated to be a viable technique with a potential to develop novel abuse-deterrent formulations. PMID:24433429

  6. Speciation of mercury and mode of transport from placer gold mine tailings

    USGS Publications Warehouse

    Slowey, A.J.; Rytuba, J.J.; Brown, Gordon E.

    2005-01-01

    Historic placer gold mining in the Clear Creek tributary to the Sacramento River (Redding, CA) has highly impacted the hydrology and ecology of an important salmonid spawning stream. Restoration of the watershed utilized dredge tailings contaminated with mercury (Hg) introduced during gold mining, posing the possibility of persistent Hg release to the surrounding environment, including the San Francisco Bay Delta. Column experiments have been performed to evaluate the extent of Hg transport under chemical conditions potentially similar to those in river restoration projects utilizing dredge tailings such as at Clear Creek. Physicochemical perturbations, in the form of shifts in column influent ionic strength and the presence of a low molecular weight organic acid, were applied to coarse and fine sand placer tailings containing 109-194 and 69-90 ng of Hg/g, respectively. Significant concentrations of mercury, up to 16 ??g/L, leach from these sediments in dissolved and particle-associated forms. Sequential chemical extractions (SCE) of these tailings indicate that elemental Hg initially introduced during gold mining has been transformed to readily soluble species, such as mercury oxides and chlorides (3-4%), intermediately extractable phases that likely include (in)organic sorption complexes and amalgams (75-87%), and fractions of highly insoluble forms such as mercury sulfides (6-20%; e.g., cinnabar and metacinnabar). Extended X-ray absorption fine structure (EXAFS) spectroscopic analysis of colloids obtained from column effluent identified cinnabar particles as the dominant mobile mercury-bearing phase. The fraction of intermediately extractable Hg phases also likely includes mobile colloids to which Hg is adsorbed. ?? 2005 American Chemical Society.

  7. Noise-Assisted Concurrent Multipath Traffic Distribution in Ad Hoc Networks

    PubMed Central

    Murata, Masayuki

    2013-01-01

    The concept of biologically inspired networking has been introduced to tackle unpredictable and unstable situations in computer networks, especially in wireless ad hoc networks where network conditions are continuously changing, resulting in the need of robustness and adaptability of control methods. Unfortunately, existing methods often rely heavily on the detailed knowledge of each network component and the preconfigured, that is, fine-tuned, parameters. In this paper, we utilize a new concept, called attractor perturbation (AP), which enables controlling the network performance using only end-to-end information. Based on AP, we propose a concurrent multipath traffic distribution method, which aims at lowering the average end-to-end delay by only adjusting the transmission rate on each path. We demonstrate through simulations that, by utilizing the attractor perturbation relationship, the proposed method achieves a lower average end-to-end delay compared to other methods which do not take fluctuations into account. PMID:24319375

  8. The automated array assembly task of the low-cost silicon solar array project, phase 2

    NASA Technical Reports Server (NTRS)

    Coleman, M. G.; Pryor, R. A.; Sparks, T. G.; Legge, R.; Saltzman, D. L.

    1980-01-01

    Several specific processing steps as part of a total process sequence for manufacturing silicon solar cells were studied. Ion implantation was identified as the preferred process step for impurity doping. Unanalyzed beam ion implantation was shown to have major cost advantages over analyzed beam implantation. Further, high quality cells were fabricated using a high current unanalyzed beam. Mechanically masked plasma patterning of silicon nitride was shown to be capable of forming fine lines on silicon surfaces with spacings between mask and substrate as great as 250 micrometers. Extensive work was performed on advances in plated metallization. The need for the thick electroless palladium layer was eliminated. Further, copper was successfully utilized as a conductor layer utilizing nickel as a barrier to copper diffusion into the silicon. Plasma etching of silicon for texturing and saw damage removal was shown technically feasible but not cost effective compared to wet chemical etching techniques.

  9. Endobronchial ultrasound-guided transbronchial needle aspiration of thyroid: Report of two cases and systematic review of literature

    PubMed Central

    Madan, Karan; Mittal, Saurabh; Hadda, Vijay; Jain, Deepali; Mohan, Anant; Guleria, Randeep

    2016-01-01

    Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive and safe technique for a sampling of mediastinal lesions. Indications for EBUS-TBNA have gradually expanded since its introduction. The usual approach to cytological sampling of the thyroid gland is percutaneous ultrasound-guided fine needle aspiration (US-FNA) performed under local anesthesia. US-FNA may be risky or not feasible in intrathoracic/substernal thyroid location. Feasibility of aspirating thyroid lesions with EBUS-TBNA has been occasionally reported. We report two patients wherein EBUS-TBNA was utilized for thyroid lesion aspiration and definitive diagnosis. We highlight the utility and safety of EBUS-TBNA in the evaluation of intrathoracic thyroid lesions wherein image-guided percutaneous aspiration may be risky/sometimes impossible to perform. A systematic review of literature has also been performed summarizing and discussing the issues pertaining to EBUS-TBNA of the thyroid gland. PMID:27891005

  10. Utilization of ethyl cellulose polymer and waste materials for roofing tile production

    NASA Astrophysics Data System (ADS)

    Sam, Suubitaa Spencer; Ng, ChoonAun; Chee, Swee Yong; Habib, NoorZainab; Nadeem, Humayon; Teoh, Wei Ping

    2017-05-01

    The aim of this study was to utilize ethyl cellulose, mixture of waste engine oil and waste vegetable oil as a binder in the environmental friendly roofing tile production. The waste engine-vegetable oil wasmix together with ethyl cellulose, fly ash, coarse aggregates, fine aggregatesand a catalyst. The Fourier Transform Infrared (FTIR) analysis showed that the oil mixture added with ethyl cellulose has the relatively high binding effect due to the presence of strong carbonyl group especially after being heat cured at 1900C for 24 hours. The mixed proportion of materials with different amount of ethyl cellulose used was studied in the production of tile specimen. The results showed that the ethyl cellulose composed roofing tile specimens passed the transverse breaking strength, durability, permeabilityand the ultraviolet accelerated test. The shrinkage on the tile can be overcome by adding temperature resistance polymer on the exterior of the tile.

  11. Importance of the gut-brain axis in the control of glucose homeostasis.

    PubMed

    Migrenne, Stéphanie; Marsollier, Nicolas; Cruciani-Guglielmacci, Céline; Magnan, Christophe

    2006-12-01

    Adult mammals finely match glucose production to glucose utilization, thus allowing glycaemia to be maintained in a physiological range of 0.8-1.2mg/dl whatever the energetic status of the mammal (i.e. fed or fasted, rested or exercised). To accomplish this, peripheral signals originating from the gut 'inform' the central nervous system, which in turn is able to monitor the status of both peripheral glucose stores and ongoing fuel availability. Indeed, both secretion and action of hormones regulating endogenous glucose production and utilization are regulated by the autonomic nervous system. These gut signals are either hormonal (e.g. glucagon-like peptide-1, ghrelin and cholecystokinine) or neuronal (e.g. afferent vagus nerve fibres). Recent data, combined with the development of incretin analogues for treatment of diabetes, highlight the importance of the gut-brain axis, especially glucagon-like peptide-1 and ghrelin, in the control of glucose homeostasis.

  12. A new experimental capability for the study of regolith surface physical properties to support science, space exploration, and in situ resource utilization (ISRU)

    NASA Astrophysics Data System (ADS)

    Dreyer, Christopher B.; Abbud-Madrid, Angel; Atkinson, Jared; Lampe, Alexander; Markley, Tasha; Williams, Hunter; McDonough, Kara; Canney, Travis; Haines, Joseph

    2018-06-01

    Many surfaces found on the Moon, asteroids, Mars, moons, and other planetary bodies are covered in a fine granular material known as regolith. Increased knowledge of the physical properties of extraterrestrial regolith surfaces will help advance the scientific knowledge of these bodies as well as the development of exploration (e.g., instrument and robotic) and in situ resource utilization (ISRU) systems. The Center for Space Resources at the Colorado School of Mines as part of the Institute for Modeling Plasma, Atmospheres, and Cosmic Dust of NASA's Solar System Exploration Research Virtual Institute has developed a novel system, called the ISRU Experimental Probe (IEP) that can support studies of dry and icy regolith from -196 to 150 °C and pressure from laboratory ambient pressure to 10-7 Torr. The IEP system and proof-of-concept results are presented in this paper.

  13. Integration of single-fiber reflectance spectroscopy into ultrasound-guided endoscopic lung cancer staging of mediastinal lymph nodes

    NASA Astrophysics Data System (ADS)

    Kanick, Stephen Chad; van der Leest, Cor; Aerts, Joachim G. J. V.; Hoogsteden, Henk C.; Kaščáková, Slávka; Sterenborg, Henricus J. C. M.; Amelink, Arjen

    2010-01-01

    We describe the incorporation of a single-fiber reflectance spectroscopy probe into the endoscopic ultrasound fine-needle aspiration (EUS-FNA) procedure utilized for lung cancer staging. A mathematical model is developed to extract information about the physiological and morphological properties of lymph tissue from single-fiber reflectance spectra, e.g., microvascular saturation, blood volume fraction, bilirubin concentration, average vessel diameter, and Mie slope. Model analysis of data from a clinical pilot study shows that the single-fiber reflectance measurement is capable of detecting differences in the physiology between normal and metastatic lymph nodes. Moreover, the clinical data show that probe manipulation within the lymph node can perturb the in vivo environment, a concern that must be carefully considered when developing a sampling strategy. The data show the feasibility of this novel technique; however, the potential clinical utility has yet to be determined.

  14. High throughput dual-wavelength temperature distribution imaging via compressive imaging

    NASA Astrophysics Data System (ADS)

    Yao, Xu-Ri; Lan, Ruo-Ming; Liu, Xue-Feng; Zhu, Ge; Zheng, Fu; Yu, Wen-Kai; Zhai, Guang-Jie

    2018-03-01

    Thermal imaging is an essential tool in a wide variety of research areas. In this work we demonstrate high-throughput double-wavelength temperature distribution imaging using a modified single-pixel camera without the requirement of a beam splitter (BS). A digital micro-mirror device (DMD) is utilized to display binary masks and split the incident radiation, which eliminates the necessity of a BS. Because the spatial resolution is dictated by the DMD, this thermal imaging system has the advantage of perfect spatial registration between the two images, which limits the need for the pixel registration and fine adjustments. Two bucket detectors, which measures the total light intensity reflected from the DMD, are employed in this system and yield an improvement in the detection efficiency of the narrow-band radiation. A compressive imaging algorithm is utilized to achieve under-sampling recovery. A proof-of-principle experiment was presented to demonstrate the feasibility of this structure.

  15. Tackling both the player and the ball: lessons from crystallographic studies on the N-utilization substance B (NusB) from Mycobacterium tuberculosis

    NASA Astrophysics Data System (ADS)

    Haire, L. F.; Gopal, B.

    2001-11-01

    The N-utilization substance B (NusB) from Mycobacterium tuberculosis is an important element in a complex assembly of other proteins and ribonucleic acid effecting transcription antitermination in this organism. The cloning and overexpression of the protein in E. coli, followed by the purification, crystallization, and use of selenomethionine samples to obtain phase information by anomalous dispersion techniques, allows us to investigate the fine interplay of sample engineering and modification of crystallization parameters leading to successful structure determination. Knowledge of the crystal structure and the surface properties of the protein allows an analysis of the packing of the NusB dimers in the crystal lattice. This exercise, albeit post facto, helps to demonstrate how biophysical and functional information could help 'rationalize' the course of obtaining protein crystals suitable for structural studies.

  16. Rare pancreatic neoplasms: the utility of endoscopic ultrasound-guided fine-needle aspiration-a large single center study.

    PubMed

    Imaoka, Hiroshi; Yamao, Kenji; Bhatia, Vikram; Shimizu, Yasuhiro; Yatabe, Yasushi; Koshikawa, Takashi; Kinoshita, Yoshikazu

    2009-01-01

    Tumors other than ductal adenocarcinomas constitute 10%-15% of all pancreatic tumors. We describe the performance and pitfalls of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for diagnosis of these rare pancreatic tumors and their characteristic cytopathological features. The records of 455 pancreatic fine-needle aspiration procedures done between March 1997 and August 2006 at Aichi Cancer Center, Nagoya, Japan, were reviewed. Besides cytology, aspirated material was routinely submitted in formalin for cell-block analysis. The reference standard for final diagnosis was surgical pathology from resected specimens. Twenty-eight rare (nonductal adenocarcinomas) pancreatic tumors were identified. Overall, EUS-FNA with the results of cytology, cell-block processing, and immunohistochemistry could correctly diagnose the type of neoplasm in 19 (67.9%) cases. EUS-FNA could distinguish benign from malignant rare tumors with a sensitivity of 69.2%, a specificity of 100%, positive predictive value of 100%, negative predictive value of 79.0%, and accuracy of 85.7%. None of three malignant pancreatic endocrine neoplasms could be diagnosed as malignant. An adequate core tissue sample could be obtained in 21 cases (75.0%) and provide a histopathological diagnosis in 19 (67.9%) cases. EUS-FNA could change the presumptive diagnosis in 11 (39.3%) cases. Specific immunochemical studies were useful adjuncts to the diagnosis. No major or minor complication was noted in any patient. Pancreatic neoplasms other than ductal adenocarcinomas have diverse imaging and histopathological features. EUS-FNA is accurate and safe for their identification.

  17. Assumption-versus data-based approaches to summarizing species' ranges.

    PubMed

    Peterson, A Townsend; Navarro-Sigüenza, Adolfo G; Gordillo, Alejandro

    2018-06-01

    For conservation decision making, species' geographic distributions are mapped using various approaches. Some such efforts have downscaled versions of coarse-resolution extent-of-occurrence maps to fine resolutions for conservation planning. We examined the quality of the extent-of-occurrence maps as range summaries and the utility of refining those maps into fine-resolution distributional hypotheses. Extent-of-occurrence maps tend to be overly simple, omit many known and well-documented populations, and likely frequently include many areas not holding populations. Refinement steps involve typological assumptions about habitat preferences and elevational ranges of species, which can introduce substantial error in estimates of species' true areas of distribution. However, no model-evaluation steps are taken to assess the predictive ability of these models, so model inaccuracies are not noticed. Whereas range summaries derived by these methods may be useful in coarse-grained, global-extent studies, their continued use in on-the-ground conservation applications at fine spatial resolutions is not advisable in light of reliance on assumptions, lack of real spatial resolution, and lack of testing. In contrast, data-driven techniques that integrate primary data on biodiversity occurrence with remotely sensed data that summarize environmental dimensions (i.e., ecological niche modeling or species distribution modeling) offer data-driven solutions based on a minimum of assumptions that can be evaluated and validated quantitatively to offer a well-founded, widely accepted method for summarizing species' distributional patterns for conservation applications. © 2016 Society for Conservation Biology.

  18. The grain-size lineup: A test of a novel eyewitness identification procedure.

    PubMed

    Horry, Ruth; Brewer, Neil; Weber, Nathan

    2016-04-01

    When making a memorial judgment, respondents can regulate their accuracy by adjusting the precision, or grain size, of their responses. In many circumstances, coarse-grained responses are less informative, but more likely to be accurate, than fine-grained responses. This study describes a novel eyewitness identification procedure, the grain-size lineup, in which participants eliminated any number of individuals from the lineup, creating a choice set of variable size. A decision was considered to be fine-grained if no more than 1 individual was left in the choice set or coarse-grained if more than 1 individual was left in the choice set. Participants (N = 384) watched 2 high-quality or low-quality videotaped mock crimes and then completed 4 standard simultaneous lineups or 4 grain-size lineups (2 target-present and 2 target-absent). There was some evidence of strategic regulation of grain size, as the most difficult lineup was associated with a greater proportion of coarse-grained responses than the other lineups. However, the grain-size lineup did not outperform the standard simultaneous lineup. Fine-grained suspect identifications were no more diagnostic than suspect identifications from standard lineups, whereas coarse-grained suspect identifications carried little probative value. Participants were generally reluctant to provide coarse-grained responses, which may have hampered the utility of the procedure. For a grain-size approach to be useful, participants may need to be trained or instructed to use the coarse-grained option effectively. (c) 2016 APA, all rights reserved).

  19. Drying of pulverized material with heated condensible vapor

    DOEpatents

    Carlson, L.W.

    1984-08-16

    Apparatus for drying pulverized material utilizes a high enthalpy condensable vapor such as steam for removing moisture from the individual particles of the pulverized material. The initially wet particulate material is tangentially delivered by a carrier vapor flow to an upper portion of a generally vertical cylindrical separation drum. The lateral wall of the separation drum is provided with a plurality of flow guides for directing the vapor tangentially therein in the direction of particulate material flow. Positioned concentrically within the separation drum and along the longitudinal axis thereof is a water-cooled condensation cylinder which is provided with a plurality of collection plates, or fines, on the outer lateral surface thereof. The cooled collection fines are aligned counter to the flow of the pulverized material and high enthalpy vapor mixture to maximize water vapor condensation thereon. The condensed liquid which includes moisture removed from the pulverized materials then flows downward along the outer surface of the coolant cylinder and is collected and removed. The particles travel in a shallow helix due to respective centrifugal and vertical acceleration forces applied thereto. The individual particles of the pulverized material are directed outwardly by the vortex flow where they contact the inner cylindrical surface of the separation drum and are then deposited at the bottom thereof for easy collection and removal. The pulverized material drying apparatus is particularly adapted for drying coal fines and facilitates the recovery of the pulverized coal. 2 figs.

  20. The use of Crumb Rubber as Substitute of Fine Aggregate for Hot Asphalt Mixture using Polymer Modified Bitumen

    NASA Astrophysics Data System (ADS)

    Setyawan, A.; Nugroho, S. K.; Irsyad, A. M.; Mutaqo, H. F.; Ramadhan, P.; Sumarsono, A.; Pramesti, F. P.

    2018-03-01

    The development of road pavement to fulfilled the need of modern life is not only focused on heavy duty road, but also a light duty road for the convenience of road users according to its function. For example the use of pavement on the jogging track, rail crossing, playground and so on. Due to the need of an alternative and the innovation of a comfortable pavement layer, but sufficiently strong in holding the load on the layer. The alternative innovation that can be used for the respective requirement is the utilization of waste old tires as substitute material in pavement construction. In this case the use of crumb rubber made from old tire rubber as an 100% fine aggregate substitute on the asphalt mixtures is investigated. To improve the strength and durability of the mixtures, the addition of polymer modified bitumen was incorporated. The two types of asphalt mixture selected in this study by using a continuous gradation of asphalt concrete and a gap gradation of hot roll asphalt. Testing to be implemented in this research is volumetric characteristics, Marshall characteristics, resistance to abrasion and impact and permeability. Replacement of fine aggregate with crumb rubber on asphalt concrete mixture with 60/70 penetration grade bitumen and polymer modified asphalt SBS E-55 in this research are expected to be an alternative in improving the quality of pavement and overcoming the environmental problems by reuse the waste materials.

  1. FIB Secondary Etching Method for Fabrication of Fine CNT Forest Metamaterials

    NASA Astrophysics Data System (ADS)

    Pander, Adam; Hatta, Akimitsu; Furuta, Hiroshi

    2017-10-01

    Anisotropic materials, like carbon nanotubes (CNTs), are the perfect substitutes to overcome the limitations of conventional metamaterials; however, the successful fabrication of CNT forest metamaterial structures is still very challenging. In this study, a new method utilizing a focused ion beam (FIB) with additional secondary etching is presented, which can obtain uniform and fine patterning of CNT forest nanostructures for metamaterials and ranging in sizes from hundreds of nanometers to several micrometers. The influence of the FIB processing parameters on the morphology of the catalyst surface and the growth of the CNT forest was investigated, including the removal of redeposited material, decreasing the average surface roughness (from 0.45 to 0.15 nm), and a decrease in the thickness of the Fe catalyst. The results showed that the combination of FIB patterning and secondary etching enabled the growth of highly aligned, high-density CNT forest metamaterials. The improvement in the quality of single-walled CNTs (SWNTs), defined by the very high G/D peak ratio intensity of 10.47, demonstrated successful fine patterning of CNT forest for the first time. With a FIB patterning depth of 10 nm and a secondary etching of 0.5 nm, a minimum size of 150 nm of CNT forest metamaterials was achieved. The development of the FIB secondary etching method enabled for the first time, the fabrication of SWNT forest metamaterials for the optical and infrared regime, for future applications, e.g., in superlenses, antennas, or thermal metamaterials.

  2. Genome-wide survey of single-nucleotide polymorphisms reveals fine-scale population structure and signs of selection in the threatened Caribbean elkhorn coral, Acropora palmata

    PubMed Central

    2017-01-01

    The advent of next-generation sequencing tools has made it possible to conduct fine-scale surveys of population differentiation and genome-wide scans for signatures of selection in non-model organisms. Such surveys are of particular importance in sharply declining coral species, since knowledge of population boundaries and signs of local adaptation can inform restoration and conservation efforts. Here, we use genome-wide surveys of single-nucleotide polymorphisms in the threatened Caribbean elkhorn coral, Acropora palmata, to reveal fine-scale population structure and infer the major barrier to gene flow that separates the eastern and western Caribbean populations between the Bahamas and Puerto Rico. The exact location of this break had been subject to discussion because two previous studies based on microsatellite data had come to differing conclusions. We investigate this contradiction by analyzing an extended set of 11 microsatellite markers including the five previously employed and discovered that one of the original microsatellite loci is apparently under selection. Exclusion of this locus reconciles the results from the SNP and the microsatellite datasets. Scans for outlier loci in the SNP data detected 13 candidate loci under positive selection, however there was no correlation between available environmental parameters and genetic distance. Together, these results suggest that reef restoration efforts should use local sources and utilize existing functional variation among geographic regions in ex situ crossing experiments to improve stress resistance of this species. PMID:29181279

  3. Copper(II)-Mediated Hydrogen Sulfide and Thiol Oxidation to Disulfides and Organic Polysulfanes and Their Reductive Cleavage in Wine: Mechanistic Elucidation and Potential Applications.

    PubMed

    Kreitman, Gal Y; Danilewicz, John C; Jeffery, David W; Elias, Ryan J

    2017-03-29

    Fermentation-derived volatile sulfur compounds (VSCs) are undesirable in wine and are often remediated in a process known as copper fining. In the present study, the addition of Cu(II) to model and real wine systems containing hydrogen sulfide (H 2 S) and thiols provided evidence for the generation of disulfides (disulfanes) and organic polysulfanes. Cu(II) fining of a white wine spiked with glutathione, H 2 S, and methanethiol (MeSH) resulted in the generation of MeSH-glutathione disulfide and trisulfane. In the present study, the mechanisms underlying the interaction of H 2 S and thiols with Cu(II) is discussed, and a prospective diagnostic test for releasing volatile sulfur compounds from their nonvolatile forms in wine is investigated. This test utilized a combination of reducing agents, metal chelators, and low-oxygen conditions to promote the release of H 2 S and MeSH, at levels above their reported sensory thresholds, from red and white wines that were otherwise free of sulfidic off-odors at the time of addition.

  4. Dual-resolution dose assessments for proton beamlet using MCNPX 2.6.0

    NASA Astrophysics Data System (ADS)

    Chao, T. C.; Wei, S. C.; Wu, S. W.; Tung, C. J.; Tu, S. J.; Cheng, H. W.; Lee, C. C.

    2015-11-01

    The purpose of this study is to access proton dose distribution in dual resolution phantoms using MCNPX 2.6.0. The dual resolution phantom uses higher resolution in Bragg peak, area near large dose gradient, or heterogeneous interface and lower resolution in the rest. MCNPX 2.6.0 was installed in Ubuntu 10.04 with MPI for parallel computing. FMesh1 tallies were utilized to record the energy deposition which is a special designed tally for voxel phantoms that converts dose deposition from fluence. 60 and 120 MeV narrow proton beam were incident into Coarse, Dual and Fine resolution phantoms with pure water, water-bone-water and water-air-water setups. The doses in coarse resolution phantoms are underestimated owing to partial volume effect. The dose distributions in dual or high resolution phantoms agreed well with each other and dual resolution phantoms were at least 10 times more efficient than fine resolution one. Because the secondary particle range is much longer in air than in water, the dose of low density region may be under-estimated if the resolution or calculation grid is not small enough.

  5. Fundamental phenomena on fuel decomposition and boundary-layer combustion processes with applications to hybrid rocket motors

    NASA Technical Reports Server (NTRS)

    Kuo, Kenneth K.; Lu, Yeu-Cherng; Chiaverini, Martin J.; Harting, George C.; Johnson, David K.; Serin, Nadir

    1995-01-01

    The experimental study on the fundamental processes involved in fuel decomposition and boundary-layer combustion in hybrid rocket motors is continuously being conducted at the High Pressure Combustion Laboratory of The Pennsylvania State University. This research will provide a useful engineering technology base in the development of hybrid rocket motors as well as a fundamental understanding of the complex processes involved in hybrid propulsion. A high-pressure, 2-D slab motor has been designed, manufactured, and utilized for conducting seven test firings using HTPB fuel processed at PSU. A total of 20 fuel slabs have been received from the Mcdonnell Douglas Aerospace Corporation. Ten of these fuel slabs contain an array of fine-wire thermocouples for measuring solid fuel surface and subsurface temperatures. Diagnostic instrumentation used in the test include high-frequency pressure transducers for measuring static and dynamic motor pressures and fine-wire thermocouples for measuring solid fuel surface and subsurface temperatures. The ultrasonic pulse-echo technique as well as a real-time x-ray radiography system have been used to obtain independent measurements of instantaneous solid fuel regression rates.

  6. Dissociated emergent-response system and fine-processing system in human neural network and a heuristic neural architecture for autonomous humanoid robots.

    PubMed

    Yan, Xiaodan

    2010-01-01

    The current study investigated the functional connectivity of the primary sensory system with resting state fMRI and applied such knowledge into the design of the neural architecture of autonomous humanoid robots. Correlation and Granger causality analyses were utilized to reveal the functional connectivity patterns. Dissociation was within the primary sensory system, in that the olfactory cortex and the somatosensory cortex were strongly connected to the amygdala whereas the visual cortex and the auditory cortex were strongly connected with the frontal cortex. The posterior cingulate cortex (PCC) and the anterior cingulate cortex (ACC) were found to maintain constant communication with the primary sensory system, the frontal cortex, and the amygdala. Such neural architecture inspired the design of dissociated emergent-response system and fine-processing system in autonomous humanoid robots, with separate processing units and another consolidation center to coordinate the two systems. Such design can help autonomous robots to detect and respond quickly to danger, so as to maintain their sustainability and independence.

  7. Experimental and Theoretical Analysis of Sound Absorption Properties of Finely Perforated Wooden Panels.

    PubMed

    Song, Boqi; Peng, Limin; Fu, Feng; Liu, Meihong; Zhang, Houjiang

    2016-11-22

    Perforated wooden panels are typically utilized as a resonant sound absorbing material in indoor noise control. In this paper, the absorption properties of wooden panels perforated with tiny holes of 1-3 mm diameter were studied both experimentally and theoretically. The Maa-MPP (micro perforated panels) model and the Maa-Flex model were applied to predict the absorption regularities of finely perforated wooden panels. A relative impedance comparison and full-factorial experiments were carried out to verify the feasibility of the theoretical models. The results showed that the Maa-Flex model obtained good agreement with measured results. Control experiments and measurements of dynamic mechanical properties were carried out to investigate the influence of the wood characteristics. In this study, absorption properties were enhanced by sound-induced vibration. The relationship between the dynamic mechanical properties and the panel mass-spring vibration absorption was revealed. While the absorption effects of wood porous structure were not found, they were demonstrated theoretically by using acoustic wave propagation in a simplified circular pipe with a suddenly changed cross-section model. This work provides experimental and theoretical guidance for perforation parameter design.

  8. A high-resolution programmable Vernier delay generator based on carry chains in FPGA

    NASA Astrophysics Data System (ADS)

    Cui, Ke; Li, Xiangyu; Zhu, Rihong

    2017-06-01

    This paper presents an architecture of a high-resolution delay generator implemented in a single field programmable gate array chip by exploiting the method of utilizing dedicated carry chains. It serves as the core component in various physical instruments. The proposed delay generator contains the coarse delay step and the fine delay step to guarantee both large dynamic range and high resolution. The carry chains are organized in the Vernier delay loop style to fulfill the fine delay step with high precision and high linearity. The delay generator was implemented in the EP3SE110F1152I3 Stratix III device from Altera on a self-designed test board. Test results show that the obtained resolution is 38.6 ps, and the differential nonlinearity/integral nonlinearity is in the range of [-0.18 least significant bit (LSB), 0.24 LSB]/(-0.02 LSB, 0.01 LSB) under the nominal supply voltage of 1100 mV and environmental temperature of 2 0°C. The delay generator is rather efficient concerning resource cost, which uses only 668 look-up tables and 146 registers in total.

  9. A stochastic model for photon noise induced by charged particles in multiplier phototubes of the space telescope fine guidance sensors

    NASA Technical Reports Server (NTRS)

    Howell, L. W.; Kennel, H. F.

    1984-01-01

    The Space Telescope (ST) is subjected to charged particle strikes in its space environment. ST's onboard fine guidance sensors utilize multiplier phototubes (PMT) for attitude determination. These tubes, when subjected to charged particle strikes, generate spurious photons in the form of Cerenkov radiation and fluorescence which give rise to unwanted disturbances in the pointing of the telescope. A stochastic model for the number of these spurious photons which strike the photocathode of the multiplier phototube which in turn produce the unwanted photon noise are presented. The model is applicable to both galactic cosmic rays and charged particles trapped in the Earth's radiation belts. The model which was programmed allows for easy adaption to a wide range of particles and different parameters for the phototube of the multiplier. The probability density functions for photons noise caused by protons, alpha particles, and carbon nuclei were using thousands of simulated strikes. These distributions are used as part of an overall ST dynamics simulation. The sensitivity of the density function to changes in the window parameters was also investigated.

  10. Stochastic model for photon noise induced by charged particles in multiplier phototubes of the Hubble Space Telescope fine guidance sensors

    NASA Technical Reports Server (NTRS)

    Howell, L. W.; Kennel, H. F.

    1986-01-01

    The Space Telescope (ST) is subjected to charged particle strikes in its space environment. ST's onboard fine guidance sensors utilize multiplier phototubes (PMT) for attitude determination. These tubes, when subjected to charged particle strikes, generate spurious photons in the form of Cerenkov radiation and fluorescence which give rise to unwanted disturbances in the pointing of the telescope. A stochastic model for the number of these spurious photons which strike the photocathodes of the multiplier phototube which in turn produce the unwanted photon noise are presented. The model is applicable to both galactic cosmic rays and charged particles trapped in the earth's radiation belts. The model which was programmed allows for easy adaption to a wide range of particles and different parameters for the phototube of the multiplier. The probability density functions for photons noise caused by protons, alpha particles, and carbon nuclei were using thousands of simulated strikes. These distributions are used as part of an overall ST dynamics simulation. The sensitivity of the density function to changes in the window parameters was also investigated.

  11. IAC Standardized Reporting of Breast Fine-Needle Aspiration Biopsy Cytology.

    PubMed

    Field, Andrew S; Schmitt, Fernando; Vielh, Philippe

    2017-01-01

    There have been many changes in the roles of fine-needle aspiration biopsy (FNAB) and core needle biopsy (CNB) in the diagnostic workup of breast lesions in routine breast clinics and in mammographic breast screening programs, as well as changes in the management algorithms utilized and the treatments available, since the NCI consensus on breast FNAB cytology in 1996. A standardized approach will improve training and performance of FNAB and smear-making techniques, and structured reporting will improve the quality and reproducibility of reports across departments, cities and countries providing a basis for quality assurance measures and improving patient care and facilitating research. Linking cytology reports to management algorithms will increase the clinicians' use of FNAB cytology and where appropriate CNB, and enhance the use of ancillary tests for prognostic testing. The IAC recognizes that the local medical infrastructure and resources for breast imaging, biopsy and treatment will influence the diagnostic workup and management of breast disease, but best practice guidelines should be established and modified as required. © 2016 S. Karger AG, Basel.

  12. Fundamental phenomena on fuel decomposition and boundary-layer combustion processes with applications to hybrid rocket motors

    NASA Astrophysics Data System (ADS)

    Kuo, Kenneth K.; Lu, Yeu-Cherng; Chiaverini, Martin J.; Harting, George C.; Johnson, David K.; Serin, Nadir

    The experimental study on the fundamental processes involved in fuel decomposition and boundary-layer combustion in hybrid rocket motors is continuously being conducted at the High Pressure Combustion Laboratory of The Pennsylvania State University. This research will provide a useful engineering technology base in the development of hybrid rocket motors as well as a fundamental understanding of the complex processes involved in hybrid propulsion. A high-pressure, 2-D slab motor has been designed, manufactured, and utilized for conducting seven test firings using HTPB fuel processed at PSU. A total of 20 fuel slabs have been received from the Mcdonnell Douglas Aerospace Corporation. Ten of these fuel slabs contain an array of fine-wire thermocouples for measuring solid fuel surface and subsurface temperatures. Diagnostic instrumentation used in the test include high-frequency pressure transducers for measuring static and dynamic motor pressures and fine-wire thermocouples for measuring solid fuel surface and subsurface temperatures. The ultrasonic pulse-echo technique as well as a real-time x-ray radiography system have been used to obtain independent measurements of instantaneous solid fuel regression rates.

  13. A study of bauxite tailing quality improvement by reverse flotation

    NASA Astrophysics Data System (ADS)

    Wulandari, W.; Purwasasmita, M.; Sanwani, E.; Malatsih, W.; Fadilla, F.

    2018-01-01

    The pre-treatment of bauxite ore from Tayan, West Kalimantan includes washing and screening fine bauxite particles (-2mm) prior as the feed to the Bayer process for producing alumina. These fine particles are believed to have high content of silica which is detrimental to the process. This washed bauxite tailing still has a significant amount of alumina content. Previous research has indicated that bauxite ore can be upgraded by applying reverse flotation method to reduce its silica content in the ore. Therefore, this study is aimed to utilize reverse flotation method to recover alumina content from washed bauxite tailing. The reverse flotation experiments were carried out at pH of 6 and 8; while the particle sizes were varied at - 140+270 mesh and -270 mesh, using a batch and circuit configuration. The result of this study shows that the batch reverse flotation can recover alumina in the tailing up to 81.4%, however the silica content is still significant. The complexity of silica-alumina minerals in the tailing prevents a complete separation of the ores by only using reverse flotation.

  14. Utility of double endoscopic intraluminal operation for esophageal cancer.

    PubMed

    Sohda, Makoto; Saito, Hideyuki; Yoshida, Tomonori; Kumakura, Yuji; Honjyo, Hiroaki; Hara, Keigo; Ozawa, Daigo; Suzuki, Shigemasa; Tanaka, Naritaka; Sakai, Makoto; Miyazaki, Tatsuya; Fukuchi, Minoru; Kuwano, Hiroyuki

    2017-08-01

    Endoscopic submucosal dissection (ESD) is a more difficult technique for esophageal cancer than for gastric cancer because the working space for esophageal ESD is small. Further, the difficulty level gradually increases depending on the size of the carcinoma. To overcome these difficulties, double endoscopic intraluminal operation (DEILO), which enables the resection of mucosal lesions using two fine endoscopes and monopolar shears, was reported previously. Here, we report the utility of DEILO for esophageal cancer. A total of 26 esophageal cancer patients (19 men and seven women) with 26 lesions treated using DEILO between 2011 and 2014 at Gunma University Hospital were included. We evaluated the utility and safety of DEILO for early esophageal cancer. For all patients (100%), the DEILO procedure was performed successfully, and en bloc resection was achieved. The median operation time, postoperative hospital stay, and the longitudinal dimension of resected specimens were 123 min (range 45-236 min), 5 days, and 32 mm, respectively. Perioperative perforation, pneumothorax, and mediastinal emphysema were not recognized. Only one patient was diagnosed with a postoperative hemorrhage, but the bleeding was successfully treated by bleeding vessel coagulation. DEILO has good utility as a technique of ESD for early esophageal cancers. Additional improvement and advancement of the procedure will increase the indication of DEILO.

  15. Parallel evolution of storage roots in morning glories (Convolvulaceae).

    PubMed

    Eserman, Lauren A; Jarret, Robert L; Leebens-Mack, James H

    2018-05-29

    Storage roots are an ecologically and agriculturally important plant trait that have evolved numerous times in angiosperms. Storage roots primarily function to store carbohydrates underground as reserves for perennial species. In morning glories, storage roots are well characterized in the crop species sweetpotato, where starch accumulates in storage roots. This starch-storage tissue proliferates, and roots thicken to accommodate the additional tissue. In morning glories, storage roots have evolved numerous times. The primary goal of this study is to understand whether this was through parallel evolution, where species use a common genetic mechanism to achieve storage root formation, or through convergent evolution, where storage roots in distantly related species are formed using a different set of genes. Pairs of species where one forms storage roots and the other does not were sampled from two tribes in the morning glory family, the Ipomoeeae and Merremieae. Root anatomy in storage roots and fine roots was examined. Furthermore, we sequenced total mRNA from storage roots and fine roots in these species and analyzed differential gene expression. Anatomical results reveal that storage roots of species in the Ipomoeeae tribe, such as sweetpotato, accumulate starch similar to species in the Merremieae tribe but differ in vascular tissue organization. In both storage root forming species, more genes were found to be upregulated in storage roots compared to fine roots. Further, we find that fifty-seven orthologous genes were differentially expressed between storage roots and fine roots in both storage root forming species. These genes are primarily involved in starch biosynthesis, regulation of starch biosynthesis, and transcription factor activity. Taken together, these results demonstrate that storage roots of species from both morning glory tribes are anatomically different but utilize a common core set of genes in storage root formation. This is consistent with a pattern of parallel evolution, thus highlighting the importance of examining anatomy together with gene expression to understand the evolutionary origins of ecologically and economically important plant traits.

  16. Engineering microbial factories for synthesis of value-added products

    PubMed Central

    Du, Jing; Shao, Zengyi; Zhao, Huimin

    2011-01-01

    Microorganisms have become an increasingly important platform for the production of drugs, chemicals, and biofuels from renewable resources. Advances in protein engineering, metabolic engineering, and synthetic biology enable redesigning microbial cellular networks and fine-tuning physiological capabilities, thus generating industrially viable strains for the production of natural and unnatural value-added compounds. In this review, we describe the recent progress on engineering microbial factories for synthesis of valued-added products including alkaloids, terpenoids, flavonoids, polyketides, non-ribosomal peptides, biofuels, and chemicals. Related topics on lignocellulose degradation, sugar utilization, and microbial tolerance improvement will also be discussed. PMID:21526386

  17. Development of a Wafer Positioning System for the Sandia Extreme Ultraviolet Lithography Tool

    NASA Technical Reports Server (NTRS)

    Wronosky, John B.; Smith, Tony G.; Darnold, Joel R.

    1996-01-01

    A wafer positioning system was recently developed by Sandia National Laboratories for an Extreme Ultraviolet Lithography (EUVL) tool. The system, which utilizes a magnetically levitated fine stage to provide ultra-precise positioning in all six degrees of freedom, incorporates technological improvements resulting from four years of prototype development. This paper describes the design, implementation, and functional capability of the system. Specifics regarding control system electronics, including software and control algorithm structure, as well as performance design goals and test results are presented. Potential system enhancements, some of which are in process, are also discussed.

  18. Calvarial tuberculosis presenting as cystic lesion: An unusual presentation in two patients.

    PubMed

    Khare, Pratima; Gupta, Renu; Chand, Priyanka; Agarwal, Swapnil

    2015-01-01

    Tuberculosis is a common disease in developing countries such as India, posing a major public health problem. With human immunodeficiency virus (HIV) infection being a global endemic, there has been a resurgence of tuberculosis even in developed countries. Tuberculosis may affect almost any part of the body. However, tuberculosis of the calvarium is very rare. Presentation of tuberculosis as a soft tissue swelling on the scalp poses a diagnostic problem. These two cases are being reported here to convey the utility of fine-needle aspiration cytology (FNAC) in providing the confirmatory diagnosis obviating the need for invasive surgical procedure.

  19. Image-based corrosion recognition for ship steel structures

    NASA Astrophysics Data System (ADS)

    Ma, Yucong; Yang, Yang; Yao, Yuan; Li, Shengyuan; Zhao, Xuefeng

    2018-03-01

    Ship structures are subjected to corrosion inevitably in service. Existed image-based methods are influenced by the noises in images because they recognize corrosion by extracting features. In this paper, a novel method of image-based corrosion recognition for ship steel structures is proposed. The method utilizes convolutional neural networks (CNN) and will not be affected by noises in images. A CNN used to recognize corrosion was designed through fine-turning an existing CNN architecture and trained by datasets built using lots of images. Combining the trained CNN classifier with a sliding window technique, the corrosion zone in an image can be recognized.

  20. Nuclear safety: is NRC enforcement working. Hearing before a Subcommittee of the Committee on Government Operations, House of Representatives, Ninety-Seventh Congress, First Session, December 14, 1981

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Nunzio Palladino, the new Chairman of the Nuclear Regulatory Commission, and associates testified at this hearing on the effectiveness of NRC's enforcement program and responded to allegations that quality assurance is inadequate. At issue were the value of NRC fines as a deterrent to utility misconduct and the NRC's reluctance to pursue new provisions for criminal penalties. Mr. Palladino was welcomed and applauded for his strong statements on the nuclear industry's need for strict quality control. (DCK)

  1. Future utilization of space: Silverton Conference on material science and phase transformations in zero-gravity, summary of proceeding

    NASA Technical Reports Server (NTRS)

    Eisner, M. (Editor)

    1975-01-01

    The importance of zero gravity environment in the development and production of new and improved materials is considered along with the gravitational effects on phase changes or critical behavior in a variety of materials. Specific experiments discussed include: fine scale phase separation in zero gravity; glass formation in zero gravity; effects of gravitational perturbations on determination of critical exponents; and light scattering from long wave fluctuations in liquids in zero gravity. It is concluded that the space shuttle/spacelab system is applicable to various fields of interest.

  2. Characterization of Si3N4/SiO2 optical channel waveguides by photon scanning tunneling microscopy

    NASA Technical Reports Server (NTRS)

    Wang, Yan; Chudgar, Mona H.; Jackson, Howard E.; Miller, Jeffrey S.; De Brabander, Gregory N.; Boyd, Joseph T.

    1993-01-01

    Photon scanning tunneling microscopy (PSTM) is used to characterize Si3N4/Si02 optical channel waveguides being used for integrated optical-micromechanical sensors. PSTM utilizes an optical fiber tapered to a fine point which is piezoelectrically positioned to measure the decay of the evanescent field intensity associated with the waveguide propagating mode. Evanescent field decays are recorded for both ridge channel waveguides and planar waveguide regions. Values for the local effective refractive index are calculated from the data for both polarizations and compared to model calculations.

  3. Sorption J-T refrigeration utilizing manganese nitride chemisorption

    NASA Technical Reports Server (NTRS)

    Jones, Jack; Lund, Alan

    1990-01-01

    The equilibrium pressures and compositions have been measured for a system of finely powdered manganese nitride and nitrogen gas at 650, 700, 800, and 850 C for various nitrogen loadings. Pressures ranged from less than 0.02 MPa at 650 C to 6.38 MPa at 850 C. Analysis of the test results has shown that under certain conditions Mn(x)N(y) could potentially be used in a triple regenerative sorption compressor refrigeration system, but the potential power savings are small compared to the increased complexity and reliability problems associated with very high temperature (above 950 C) pressurized systems.

  4. Acoustic structure and propagation in highly porous, layered, fibrous materials

    NASA Technical Reports Server (NTRS)

    Lambert, R. F.; Tesar, J. S.

    1984-01-01

    The acoustic structure and propagation of sound in highly porous, layered, fine fiber materials is examined. Of particular interest is the utilization of the Kozeny number for determining the static flow resistance and the static structure factor based on flow permeability measurements. In this formulation the Kozeny number is a numerical constant independent of volume porosity at high porosities. The other essential parameters are then evaluated employing techniques developed earlier for open cell foams. The attenuation and progressive phase characteristics in bulk samples are measured and compared with predicted values. The agreements on the whole are very satisfactory.

  5. Cold molecule spectroscopy for constraining the evolution of the fine structure constant.

    PubMed

    Hudson, Eric R; Lewandowski, H J; Sawyer, Brian C; Ye, Jun

    2006-04-14

    We report precise measurements of ground-state, Lambda-doublet microwave transitions in the hydroxyl radical molecule (OH). Utilizing slow, cold molecules produced by a Stark decelerator we have improved over the precision of the previous best measurement 25-fold for the F'=2-->F=2 transition, yielding (1 667 358 996 +/- 4)Hz, and by tenfold for the F'=1-->F=1 transition, yielding (1 665 401 803 +/-12)Hz. Comparing these laboratory frequencies to those from OH megamasers in interstellar space will allow a sensitivity of 1 ppm for Delta(alpha/alpha) over approximately 10(10) yr.

  6. Origins of the plant chloroplasts and mitochondria based on comparisons of 5S ribosomal RNAs

    NASA Technical Reports Server (NTRS)

    Delihas, N.; Fox, G. E.

    1987-01-01

    In this paper, we provide macromolecular comparisons utilizing the 5S ribosomal RNA structure to suggest extant bacteria that are the likely descendants of chloroplast and mitochondria endosymbionts. The genetic stability and near universality of the 5S ribosomal gene allows for a useful means to study ancient evolutionary changes by macromolecular comparisons. The value in current and future ribosomal RNA comparisons is in fine tuning the assignment of ancestors to the organelles and in establishing extant species likely to be descendants of bacteria involved in presumed multiple endosymbiotic events.

  7. Pupil-segmentation-based adaptive optical correction of a high-numerical-aperture gradient refractive index lens for two-photon fluorescence endoscopy.

    PubMed

    Wang, Chen; Ji, Na

    2012-06-01

    The intrinsic aberrations of high-NA gradient refractive index (GRIN) lenses limit their image quality as well as field of view. Here we used a pupil-segmentation-based adaptive optical approach to correct the inherent aberrations in a two-photon fluorescence endoscope utilizing a 0.8 NA GRIN lens. By correcting the field-dependent aberrations, we recovered diffraction-limited performance across a large imaging field. The consequent improvements in imaging signal and resolution allowed us to detect fine structures that were otherwise invisible inside mouse brain slices.

  8. Grid computing in large pharmaceutical molecular modeling.

    PubMed

    Claus, Brian L; Johnson, Stephen R

    2008-07-01

    Most major pharmaceutical companies have employed grid computing to expand their compute resources with the intention of minimizing additional financial expenditure. Historically, one of the issues restricting widespread utilization of the grid resources in molecular modeling is the limited set of suitable applications amenable to coarse-grained parallelization. Recent advances in grid infrastructure technology coupled with advances in application research and redesign will enable fine-grained parallel problems, such as quantum mechanics and molecular dynamics, which were previously inaccessible to the grid environment. This will enable new science as well as increase resource flexibility to load balance and schedule existing workloads.

  9. Multivariate analysis of fatty acid and biochemical constitutes of seaweeds to characterize their potential as bioresource for biofuel and fine chemicals.

    PubMed

    Verma, Priyanka; Kumar, Manoj; Mishra, Girish; Sahoo, Dinabandhu

    2017-02-01

    In the present study bio prospecting of thirty seaweeds from Indian coasts was analyzed for their biochemical components including pigments, fatty acid and ash content. Multivariate analysis of biochemical components and fatty acids was done using Principal Component Analysis (PCA) and Agglomerative hierarchical clustering (AHC) to manifest chemotaxonomic relationship among various seaweeds. The overall analysis suggests that these seaweeds have multi-functional properties and can be utilized as promising bioresource for proteins, lipids, pigments and carbohydrates for the food/feed and biofuel industry. Copyright © 2016. Published by Elsevier Ltd.

  10. Risk stratification of thyroid nodules on ultrasonography with the French TI-RADS: description and reflections

    PubMed Central

    2016-01-01

    The widespread use of ultrasonography places it in a key position for use in the risk stratification of thyroid nodules. The French proposal is a five-tier system, our version of a thyroid imaging reporting and database system (TI-RADS), which includes a standardized vocabulary and report and a quantified risk assessment. It allows the selection of the nodules that should be referred for fine-needle aspiration biopsies. Effort should be directed towards merging the different risk stratification systems utilized around the world and testing this unified system with multi-center studies. PMID:26324117

  11. Supporting Building Portfolio Investment and Policy Decision Making through an Integrated Building Utility Data Platform

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aziz, Azizan; Lasternas, Bertrand; Alschuler, Elena

    The American Recovery and Reinvestment Act stimulus funding of 2009 for smart grid projects resulted in the tripling of smart meters deployment. In 2012, the Green Button initiative provided utility customers with access to their real-time1 energy usage. The availability of finely granular data provides an enormous potential for energy data analytics and energy benchmarking. The sheer volume of time-series utility data from a large number of buildings also poses challenges in data collection, quality control, and database management for rigorous and meaningful analyses. In this paper, we will describe a building portfolio-level data analytics tool for operational optimization, businessmore » investment and policy assessment using 15-minute to monthly intervals utility data. The analytics tool is developed on top of the U.S. Department of Energy’s Standard Energy Efficiency Data (SEED) platform, an open source software application that manages energy performance data of large groups of buildings. To support the significantly large volume of granular interval data, we integrated a parallel time-series database to the existing relational database. The time-series database improves on the current utility data input, focusing on real-time data collection, storage, analytics and data quality control. The fully integrated data platform supports APIs for utility apps development by third party software developers. These apps will provide actionable intelligence for building owners and facilities managers. Unlike a commercial system, this platform is an open source platform funded by the U.S. Government, accessible to the public, researchers and other developers, to support initiatives in reducing building energy consumption.« less

  12. The cost-effectiveness of fine-needle aspiration cytology and 14-gauge core needle biopsy compared with open surgical biopsy in the diagnosis of breast carcinoma.

    PubMed

    Logan-Young, W; Dawson, A E; Wilbur, D C; Avila, E E; Tomkiewicz, Z M; Sheils, L A; Laczin, J A; Taylor, A S

    1998-05-15

    Judicious utilization of fine-needle aspiration cytology (FNAC) and 14-gauge core needle biopsy (CB) theoretically should result in greater accuracy in breast carcinoma diagnosis and fewer unnecessary open surgical biopsies (OSBs), thus lowering health care costs. In 1995 in Rochester, New York, the ratio of open surgical breast biopsies per each verified breast carcinoma (OSB/Ca) in a freestanding breast clinic (EWBC) was compared with the OSB/Ca ratio of all physicians in the remainder of the city. The EWBC differs from all other diagnostic facilities in Rochester in that it routinely performs FNAC and CB. The EWBC recommended 462 OSBs resulting in 310 verified carcinomas, for a OSB/Ca ratio of 1.5. The physicians in the remainder of the city recommended 2036 OSBs resulting in 513 verified carcinomas, for a OSB/Ca ratio of 4.0. If the EWBC OSB/Ca ratio had been identical to the remainder of the city, the number of extra OSBs recommended by the clinic would have been 778, resulting in an additional cost of $1,712,082. When the added cost of the 2594 FNACs ($256,285) and 403 CBs ($252,278) performed by the clinic was subtracted from the $1,712,082, the freestanding breast clinic cost savings was $1,203,519. The lymph node metastasis rate of 19% for the breast carcinomas diagnosed in clinic patients was identical to that of the women with breast carcinoma in the remainder of the city. Utilization of FNAC and CB allows radiologists to lower their OSB/Ca ratio without sacrificing early detection. In this study, these less expensive procedures result in lowered medical costs for the health care system.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levendis, Y.A.; Zhu, W.; Wise, D.L.

    A fundamental study was conducted on the effectiveness of the chemical calcium magnesium acetate (CMA) as a sulfur capture agent during combustion of pulverized coal. It was based on high-temperature laboratory-bench experiments with the scope of exploring the use of CMA as a dry scrubbing'' medium for in-boiler injection. Two methods of CMA introduction in the furnace were considered: dry-spraying fine powders of the chemical and wet-spraying aqueous solutions to generate fine aerosols. It considered conditions pertinent to post-flame in-boiler injection of CMA to identify optimum temperatures and residence times. In addition to the versatility of the water-soluble CMA tomore » enable spray drying injection and therefore eliminate grinding costs, there are other attractive features. Mainly, its ability to form highly cenospheric, popcorn''-like, oxide particles on heating to high temperatures. These cenospheres possess thin, porous walls with blowholes that enable penetration of the SO[sub 2] in the interior of the particle which promotes high sorbent utilization. SO[sub 2] captures in the order of 90% were achieved with dry-injection of the chemical at furnace gas temperatures of about 1,000[degree]C, a Ca/S ratio of 2, and particle size of [approximately] 50[mu]m. Moreover, CMA was superior (by over 40%) to either CaCO[sub 3] or Ca(OH)[sub 2] in sulfur capture effectiveness per unit mass of calcium. This commercially obtained CMA was even superior to reagent-grade calcium acetate (by as much as 30%), again per unit mass of calcium. The utilization of CMA and calcium acetate depended on the cenosphere wall thickness, rather than the particle size and, thus, outperformed other sorbents regardless of the size of the resulting oxide particles.« less

  14. Breast fine-needle aspiration samples reported as "proliferative breast lesion": clinical utility of the subcategory "proliferative breast lesion with atypia".

    PubMed

    Zhao, Chengquan; Raza, Anwar; Martin, Sue E; Pan, Jiangqiu; Greaves, Timothy S; Cobb, Camilla J

    2009-04-25

    The fine-needle aspiration (FNA) diagnosis of proliferative breast lesion is an indeterminate category. The aim of this correlative study was to determine whether a subcategory of "proliferative breast lesion with atypia" was achievable and whether this subcategory has management utility. Breast FNA cases from 2000 through 2005 diagnosed as proliferative breast lesion and proliferative breast lesion with atypia were retrieved. Both cytologic and surgical slides of these cases were reviewed blindly. A cytologic diagnosis of proliferative breast lesion (without atypia) or proliferative breast lesion with atypia was used if the findings of the proliferative breast lesion did not fit a more specific category. Of the 3934 breast FNAs performed on palpable breast masses from January 2000 to December 2005 at the LAC + USC Medical Center, 317 (8.1%) were diagnosed cytologically as proliferative breast lesion with atypia, without atypia or without mention of atypia. There was subsequent histopathology on 201 of these cases. After the cytologic smears were reviewed, 29 cases were excluded from this study. Of the 172 remaining cases, 21 (12.2%) were found to be malignant and the remaining 151 (87.8%) were found to be benign on histology. Of the malignant cases, 90% had an FNA diagnosis of proliferative breast lesion with atypia; of the benign cases, 78% were interpreted as proliferative breast lesion without atypia. Proliferative breast lesion with atypia was clinically significant because it was associated with a significantly increased likelihood of malignancy compared with proliferative breast lesion without atypia. Most of the malignancies had hypocellularity or low nuclear grade on the FNA smears. Fibroadenoma accounted for most of the benign lesions in both proliferative breast lesion and proliferative breast lesion with atypia. (c) 2009 American Cancer Society.

  15. Effects of corn particle size and source on performance of lactating cows fed direct-cut grass-legume forage.

    PubMed

    Reis, R B; Emeterio, F S; Combs, D K; Satter, L D; Costa, H N

    2001-02-01

    We conducted two experiments to evaluate the effects of corn supplementation, source of corn, and corn particle size on performance and nutrient utilization of lactating dairy cows. In experiment 1, treatments were 1) direct-cut grass-legume forage without supplement, 2) direct-cut forage plus 10 kg DM of ground dry shelled corn-based concentrate, and 3) direct-cut forage plus 10 kg DM of coarsely ground high moisture ear corn-based concentrate. In experiment 2, treatments were 1) direct-cut grass-legume forage plus 10 kg DM of ground dry shelled corn-based concentrate, 2) direct-cut forage plus 10 kg DM of coarsely ground high moisture ear corn-based concentrate, and 3) direct-cut forage plus 10 kg of DM finely ground high moisture ear corn-based concentrate. Both experiments were designed as 3 x 3 Latin squares replicated three times. In experiment 1, yields of milk and milk protein increased with concentrate supplementation, but were not affected by source of corn. Solids-corrected milk yield tended to increase with grain supplementation. Dry matter intake increased with concentrate supplementation, but was not affected by source of corn or corn particle size. Corn supplements decreased ruminal pH and acetate to propionate ratio and increased ruminal propionate concentration. Grain supplements reduced ruminal ammonia concentration, increased concentration of urine allantoin, and increased the urinary allantoin to creatinine ratio. In the second study, fine grinding of high moisture corn reduced fecal starch plus free glucose levels and tended to increase its apparent digestibility. In both experiments, starch plus free glucose intake was higher on the diets with dry corn, but its utilization was not affected by source of corn.

  16. Clinical utility of routine pre-operative axillary ultrasound and fine needle aspiration cytology in patient selection for sentinel lymph node biopsy.

    PubMed

    Rattay, T; Muttalib, M; Khalifa, E; Duncan, A; Parker, S J

    2012-04-01

    In patients with operable breast cancer, pre-operative evaluation of the axilla may be of use in the selection of appropriate axillary surgery. Pre-operative axillary ultrasound (US) and fine needle aspiration cytology (FNAC) assessments have become routine practice in many breast units, although the evidence base is still gathering. This study assessed the clinical utility of US+/-FNAC in patient selection for either axillary node clearance (ANC) or sentinel lymph node biopsy (SLNB) in patients undergoing surgery for operable breast cancer. Over a two-year period, 348 patients with a clinically negative axilla underwent axillary US. 67 patients with suspicious nodes on US also underwent FNAC. The sensitivity and specificity of axillary investigations to determine nodal involvement were 56% (confidence interval: 47-64%) and 90% (84-93%) for US alone, and 76% (61-87%) and 100% (65-100%) for FNAC combined with US, respectively. With a positive US, the post-test probability was 78%. A negative US carried a post-test probability of 25%. When FNAC was positive, the post-test probability was greater than unity. A negative FNAC yielded a post-test probability of 52%. All patients with positive FNAC and most patients with suspicious US were listed for axillary node clearance (ANC) after consideration at the multi-disciplinary team (MDT) meeting. With pre-operative axillary US+/-FNAC, 20% of patients were saved a potential second axillary procedure, facilitating a reduction in the overall re-operation rate to 12%. In this study, a positive pre-operative US+/-FNAC directs patients towards ANC. When the result is negative, other clinico-pathological factors need to be taken into account in the selection of the appropriate axillary procedure. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. Exploiting sequence similarity to validate the sensitivity of SNP arrays in detecting fine-scaled copy number variations.

    PubMed

    Wong, Gerard; Leckie, Christopher; Gorringe, Kylie L; Haviv, Izhak; Campbell, Ian G; Kowalczyk, Adam

    2010-04-15

    High-density single nucleotide polymorphism (SNP) genotyping arrays are efficient and cost effective platforms for the detection of copy number variation (CNV). To ensure accuracy in probe synthesis and to minimize production costs, short oligonucleotide probe sequences are used. The use of short probe sequences limits the specificity of binding targets in the human genome. The specificity of these short probeset sequences has yet to be fully analysed against a normal reference human genome. Sequence similarity can artificially elevate or suppress copy number measurements, and hence reduce the reliability of affected probe readings. For the purpose of detecting narrow CNVs reliably down to the width of a single probeset, sequence similarity is an important issue that needs to be addressed. We surveyed the Affymetrix Human Mapping SNP arrays for probeset sequence similarity against the reference human genome. Utilizing sequence similarity results, we identified a collection of fine-scaled putative CNVs between gender from autosomal probesets whose sequence matches various loci on the sex chromosomes. To detect these variations, we utilized our statistical approach, Detecting REcurrent Copy number change using rank-order Statistics (DRECS), and showed that its performance was superior and more stable than the t-test in detecting CNVs. Through the application of DRECS on the HapMap population datasets with multi-matching probesets filtered, we identified biologically relevant SNPs in aberrant regions across populations with known association to physical traits, such as height, covered by the span of a single probe. This provided empirical confirmation of the existence of naturally occurring narrow CNVs as well as the sensitivity of the Affymetrix SNP array technology in detecting them. The MATLAB implementation of DRECS is available at http://ww2.cs.mu.oz.au/ approximately gwong/DRECS/index.html.

  18. Fine needle aspiration cytology of oral and oropharyngeal lesions with an emphasis on the diagnostic utility and pitfalls.

    PubMed

    Gupta, Nalini; Banik, Tarak; Rajwanshi, Arvind; Radotra, Bishan D; Panda, Naresh; Dey, Pranab; Srinivasan, Radhika; Nijhawan, Raje

    2012-01-01

    This study was undertaken to evaluate the diagnostic utility and pitfalls of fine needle aspiration cytology (FNAC) in oral and oropharyngeal lesions. This was a retrospective audit of oral and oropharyngeal lesions diagnosed with FNAC over a period of six years (2005-2010). Oral/oropharyngeal lesions [n=157] comprised 0.35% of the total FNAC load. The age ranged 1-80 years with the male: female ratio being 1.4:1. Aspirates were inadequate in 7% cases. Histopathology was available in 73/157 (46.5%) cases. Palate was the most common site of involvement [n=66] followed by tongue [n=35], buccal mucosa [n=18], floor of the mouth [n=17], tonsil [n=10], alveolus [n=5], retromolar trigone [n=3], and posterior pharyngeal wall [n=3]. Cytodiagnoses were categorized into infective/inflammatory lesions and benign cysts, and benign and malignant tumours. Uncommon lesions included ectopic lingual thyroid and adult rhabdomyoma of tongue, and solitary fibrous tumor (SFT), and leiomyosarcoma in buccal mucosa. A single false-positive case was dense inflammation with squamous cells misinterpreted as squamous cell carcinoma (SCC) on cytology. There were eight false-negative cases mainly due to sampling error. One false-negative case due to interpretation error was in a salivary gland tumor. The sensitivity of FNAC in diagnosing oral/oropharyngeal lesions was 71.4%; specificity was 97.8% with diagnostic accuracy of 87.7%. Salivary gland tumors and squamous cell carcinoma (SCC) are the most common lesions seen in the oral cavity. FNAC proves to be highly effective in diagnosing the spectrum of different lesions in this region. Sampling error is the main cause of false-negative cases in this region.

  19. Indirect estimation of absorption properties for fine aerosol particles using AATSR observations: a case study of wildfires in Russia in 2010

    NASA Astrophysics Data System (ADS)

    Rodriguez, E.; Kolmonen, P.; Virtanen, T. H.; Sogacheva, L.; Sundstrom, A.-M.; de Leeuw, G.

    2015-08-01

    The Advanced Along-Track Scanning Radiometer (AATSR) on board the ENVISAT satellite is used to study aerosol properties. The retrieval of aerosol properties from satellite data is based on the optimized fit of simulated and measured reflectances at the top of the atmosphere (TOA). The simulations are made using a radiative transfer model with a variety of representative aerosol properties. The retrieval process utilizes a combination of four aerosol components, each of which is defined by their (lognormal) size distribution and a complex refractive index: a weakly and a strongly absorbing fine-mode component, coarse mode sea salt aerosol and coarse mode desert dust aerosol). These components are externally mixed to provide the aerosol model which in turn is used to calculate the aerosol optical depth (AOD). In the AATSR aerosol retrieval algorithm, the mixing of these components is decided by minimizing the error function given by the sum of the differences between measured and calculated path radiances at 3-4 wavelengths, where the path radiances are varied by varying the aerosol component mixing ratios. The continuous variation of the fine-mode components allows for the continuous variation of the fine-mode aerosol absorption. Assuming that the correct aerosol model (i.e. the correct mixing fractions of the four components) is selected during the retrieval process, also other aerosol properties could be computed such as the single scattering albedo (SSA). Implications of this assumption regarding the ratio of the weakly/strongly absorbing fine-mode fraction are investigated in this paper by evaluating the validity of the SSA thus obtained. The SSA is indirectly estimated for aerosol plumes with moderate-to-high AOD resulting from wildfires in Russia in the summer of 2010. Together with the AOD, the SSA provides the aerosol absorbing optical depth (AAOD). The results are compared with AERONET data, i.e. AOD level 2.0 and SSA and AAOD inversion products. The RMSE (root mean square error) is 0.03 for SSA and 0.02 for AAOD lower than 0.05. The SSA is further evaluated by comparison with the SSA retrieved from the Ozone Monitoring Instrument (OMI). The SSA retrieved from both instruments show similar features, with generally lower AATSR-estimated SSA values over areas affected by wildfires.

  20. Dust Tolerant Commodity Transfer Interface Mechanisms for Planetary Surfaces

    NASA Technical Reports Server (NTRS)

    Townsend, Ivan I.; Mueller, Robert P.; Tamasy, Gabor J.

    2014-01-01

    Regolith is present on most planetary surfaces such as Earth's moon, Mars, and Asteroids. If human crews and robotic machinery are to operate on these regolith covered surfaces, they must face the consequences of interacting with regolith fines which consist of particles below 100 microns in diameter down to as small as submicron scale particles. Such fine dust will intrude into mechanisms and interfaces causing a variety of problems such as contamination of clean fluid lines, jamming of mechanisms and damaging connector seals and couplings. Since multiple elements must be assembled in space for system level functionality, it will be inevitable that interfaces will be necessary for structural connections, and to pass commodities such as cryogenic liquid propellants, purge and buffer gases, water, breathing air, pressurizing gases, heat exchange fluids, power and data. When fine regolith dust is present in the environment it can be lofted into interfaces where it can compromise the utility of the interface by preventing the connections from being successfully mated, or by inducing fluid leaks or degradation of power and data transmission. A dust tolerant, hand held "quick-disconnect" cryogenic fluids connector housing has been developed at NASA KSC which can be used by astronaut crews to connect flex lines that will transfer propellants and other useful fluids to the end user. In addition, a dust tolerant, automated, cryogenic fluid, multiple connector, power and data interface mechanism prototype has been developed, fabricated and demonstrated by NASA at Kennedy Space Center (KSC). The design and operation of these prototypes are explained and discussed.

  1. Hierarchical classification of land use types using multiple vegetation indices to measure the effects of urbanization.

    PubMed

    Shishir, Sharmin; Tsuyuzaki, Shiro

    2018-05-11

    Detecting fine-scale spatiotemporal land use changes is a prerequisite for understanding and predicting the effects of urbanization and its related human impacts on the ecosystem. Land use changes are frequently examined using vegetation indices (VIs), although the validation of these indices has not been conducted at a high resolution. Therefore, a hierarchical classification was constructed to obtain accurate land use types at a fine scale. The characteristics of four popular VIs were investigated prior to examining the hierarchical classification by using Purbachal New Town, Bangladesh, which exhibits ongoing urbanization. These four VIs are the normalized difference VI (NDVI), green-red VI (GRVI), enhanced VI (EVI), and two-band EVI (EVI2). The reflectance data were obtained by the IKONOS (0.8-m resolution) and WorldView-2 sensor (0.5-m resolution) in 2001 and 2015, respectively. The hierarchical classification of land use types was constructed using a decision tree (DT) utilizing all four of the examined VIs. The accuracy of the classification was evaluated using ground truth data with multiple comparisons and kappa (κ) coefficients. The DT showed overall accuracies of 96.1 and 97.8% in 2001 and 2015, respectively, while the accuracies of the VIs were less than 91.2%. These results indicate that each VI exhibits unique advantages. In addition, the DT was the best classifier of land use types, particularly for native ecosystems represented by Shorea forests and homestead vegetation, at the fine scale. Since the conservation of these native ecosystems is of prime importance, DTs based on hierarchical classifications should be used more widely.

  2. Evaluation of recycled concrete aggregates for their suitability in construction activities: An experimental study.

    PubMed

    Puthussery, Joseph V; Kumar, Rakesh; Garg, Anurag

    2017-02-01

    Construction and demolition waste disposal is a major challenge in developing nations due to its ever increasing quantities. In this study, the recycling potential of waste concrete as aggregates in construction activities was studied. The metal leaching from the recycled concrete aggregates (RCA) collected from the demolition site of a 50year old building, was evaluated by performing three different leaching tests (compliance, availability and Toxic Characteristic Leaching Procedure). The metal leaching was found mostly within the permissible limit except for Hg. Several tests were performed to determine the physical and mechanical properties of the fine and coarse aggregates produced from recycled concrete. The properties of recycled aggregates were found to be satisfactory for their utilization in road construction activities. The suitability of using recycled fine and coarse aggregates with Portland pozzolanic cement to make a sustainable and environmental friendly concrete mix design was also analyzed. No significant difference was observed in the compressive strength of various concrete mixes prepared by natural and recycled aggregates. However, only the tensile strength of the mix prepared with 25% recycled fine aggregates was comparable to that of the control concrete. For other mixes, the tensile strength of the concrete was found to drop significantly. In summary, RCA should be considered seriously as a building material for road construction, mass concrete works, lightly reinforced sections, etc. The present work will be useful for the waste managers and policy makers particularly in developing nations where proper guidelines are still lacking. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Fine structure and optical properties of biological polarizers in crustaceans and cephalopods

    NASA Astrophysics Data System (ADS)

    Chiou, Tsyr-Huei; Caldwell, Roy L.; Hanlon, Roger T.; Cronin, Thomas W.

    2008-04-01

    The lighting of the underwater environment is constantly changing due to attenuation by water, scattering by suspended particles, as well as the refraction and reflection caused by the surface waves. These factors pose a great challenge for marine animals which communicate through visual signals, especially those based on color. To escape this problem, certain cephalopod mollusks and stomatopod crustaceans utilize the polarization properties of light. While the mechanisms behind the polarization vision of these two animal groups are similar, several distinctive types of polarizers (i.e. the structure producing the signal) have been found in these animals. To gain a better knowledge of how these polarizers function, we studied the relationships between fine structures and optical properties of four types of polarizers found in cephalopods and stomatopods. Although all the polarizers share a somewhat similar spectral range, around 450- 550 nm, the reflectance properties of the signals and the mechanisms used to produce them have dramatic differences. In cephalopods, stack-plates polarizers produce the polarization patterns found on the arms and around their eyes. In stomatopods, we have found one type of beam-splitting polarizer based on photonic structures and two absorptive polarizer types based on dichroic molecules. These stomatopod polarizers may be found on various appendages, and on the cuticle covering dorsal or lateral sides of the animal. Since the efficiencies of all these polarizer types are somewhat sensitive to the change of illumination and viewing angle, how these animals compensate with different behaviors or fine structural features of the polarizer also varies.

  4. Li 2S encapsulated by nitrogen-doped carbon for lithium sulfur batteries

    DOE PAGES

    Chen, Lin; Liu, Yuzi; Ashuri, Maziar; ...

    2014-09-26

    Using high-energy ball milling of the Li 2S plus carbon black mixture followed by carbonization of pyrrole, we have established a facile approach to synthesize Li 2S-plus-C composite particles of average size 400 nm, encapsulated by a nitrogen-doped carbon shell. Such an engineered core–shell structure exhibits an ultrahigh initial discharge specific capacity (1029 mAh/g), reaching 88% of the theoretical capacity (1,166 mAh/g of Li 2S) and thus offering the highest utilization of Li 2S in the cathode among all of the reported works for the encapsulated Li 2S cathodes. This Li 2S/C composite core with a nitrogen-doped carbon shell canmore » still retain 652 mAh/g after prolonged 100 cycles. These superior properties are attributed to the nitrogen-doped carbon shell that can improve the conductivity to enhance the utilization of Li 2S in the cathode. As a result, fine particle sizes and the presence of carbon black within the Li 2S core may also play a role in high utilization of Li 2S in the cathode.« less

  5. Telepathology in cytopathology: challenges and opportunities.

    PubMed

    Collins, Brian T

    2013-01-01

    Telepathology in cytopathology is becoming more commonly utilized, and newer technologic infrastructures afford the laboratory a variety of options. The options and design of a telepathology system are driven by the clinical needs. This is primarily focused on providing rapid on-site evaluation service for fine needle aspiration. The clinical requirements and needs of a system are described. Available tools to design and implement a telepathology system are covered, including methods of image capture, network connectivity and remote viewing options. The primary telepathology method currently used and described involves the delivery via a network connection of a live video image to a remote site which is passively viewed by an internet web-based browser. By utilizing live video information and a voice connection to the on-site location, the remote viewer can collect clinical information and direct their view of the slides. Telepathology systems for use in cytopathology can be designed and implemented with commercially available infrastructure. It is necessary for the laboratory to validate the designed system and adhere to the required regulatory requirements. Telepathology for cytopathology can be reliably utilized by adapting existing technology, and newer advances hold great promise for further applications in the cytopathology laboratory. Copyright © 2013 S. Karger AG, Basel.

  6. Demonstration of a Balloon Borne Arc-Second Pointer Design

    NASA Technical Reports Server (NTRS)

    DeWeese, Keith D.; Ward, Philip R.

    2006-01-01

    Many designs for utilizing stratospheric balloons as low-cost platforms on which to conduct space science experiments have been proposed throughout the years. A major hurdle in extending the range of experiments for which these vehicles are useful has been the imposition of the gondola dynamics on the accuracy with which an instrument can be kept pointed at a celestial target. A significant number of scientists have sought the ability to point their instruments with jitter in the arc-second range. This paper presents the design and analysis of a stratospheric balloon borne pointing system that is able to meet this requirement. The test results of a demonstration prototype of the design with similar ability are also presented. Discussion of a high fidelity controller simulation for design analysis is presented. The flexibility of the flight train is represented through generalized modal analysis. A multiple controller scheme is utilized for coarse and fine pointing. Coarse azimuth pointing is accomplished by an established pointing system, with extensive flight history, residing above the gondola structure. A pitch-yaw gimbal mount is used for fine pointing, providing orthogonal axes when nominally on target. Fine pointing actuation is from direct drive dc motors, eliminating backlash problems. An analysis of friction nonlinearities and a demonstration of the necessity in eliminating static friction are provided. A unique bearing hub design is introduced that eliminates static friction from the system dynamics. A control scheme involving linear accelerometers for enhanced disturbance rejection is also presented. Results from a linear analysis of the total system and the high fidelity simulation are given. Results from a generalized demonstration prototype are presented. Commercial off-the-shelf (COTS) hardware was used to demonstrate the efficacy and performance of the pointer design for a mock instrument. Sub-arcsecond pointing ability from a ground hang test setup is shown from the testing results. This paper establishes that the proposed control strategy can be made robustly stable with significant design margins. Also demonstrated is the efficacy of the proposed system in rejecting disturbances larger than those considered realistic. The system is implemented and demonstrates sub arc second pointing ability using COTS hardware. Finally, we see that sub arc-second pointing stability can be achieved for a large instrument pointing at an inertial target.

  7. The Transition of NASA EOS Datasets to WFO Operations: A Model for Future Technology Transfer

    NASA Technical Reports Server (NTRS)

    Darden, C.; Burks, J.; Jedlovec, G.; Haines, S.

    2007-01-01

    The collocation of a National Weather Service (NWS) Forecast Office with atmospheric scientists from NASA/Marshall Space Flight Center (MSFC) in Huntsville, Alabama has afforded a unique opportunity for science sharing and technology transfer. Specifically, the NWS office in Huntsville has interacted closely with research scientists within the SPORT (Short-term Prediction and Research and Transition) Center at MSFC. One significant technology transfer that has reaped dividends is the transition of unique NASA EOS polar orbiting datasets into NWS field operations. NWS forecasters primarily rely on the AWIPS (Advanced Weather Information and Processing System) decision support system for their day to day forecast and warning decision making. Unfortunately, the transition of data from operational polar orbiters or low inclination orbiting satellites into AWIPS has been relatively slow due to a variety of reasons. The ability to integrate these high resolution NASA datasets into operations has yielded several benefits. The MODIS (MODerate-resolution Imaging Spectrometer ) instrument flying on the Aqua and Terra satellites provides a broad spectrum of multispectral observations at resolutions as fine as 250m. Forecasters routinely utilize these datasets to locate fine lines, boundaries, smoke plumes, locations of fog or haze fields, and other mesoscale features. In addition, these important datasets have been transitioned to other WFOs for a variety of local uses. For instance, WFO Great Falls Montana utilizes the MODIS snow cover product for hydrologic planning purposes while several coastal offices utilize the output from the MODIS and AMSR-E instruments to supplement observations in the data sparse regions of the Gulf of Mexico and western Atlantic. In the short term, these datasets have benefited local WFOs in a variety of ways. In the longer term, the process by which these unique datasets were successfully transitioned to operations will benefit the planning and implementation of products and datasets derived from both NPP and NPOESS. This presentation will provide a brief overview of current WFO usage of satellite data, the transition of datasets between SPORT and the N W S , and lessons learned for future transition efforts.

  8. Aluminium tolerance and high phosphorus efficiency helps Stylosanthes better adapt to low-P acid soils.

    PubMed

    Du, Yu-Mei; Tian, Jiang; Liao, Hong; Bai, Chang-Jun; Yan, Xiao-Long; Liu, Guo-Dao

    2009-06-01

    Stylosanthes spp. (stylo) is one of the most important pasture legumes used in a wide range of agricultural systems on acid soils, where aluminium (Al) toxicity and phosphorus (P) deficiency are two major limiting factors for plant growth. However, physiological mechanisms of stylo adaptation to acid soils are not understood. Twelve stylo genotypes were surveyed under field conditions, followed by sand and nutrient solution culture experiments to investigate possible physiological mechanisms of stylo adaptation to low-P acid soils. Stylo genotypes varied substantially in growth and P uptake in low P conditions in the field. Three genotypes contrasting in P efficiency were selected for experiments in nutrient solution and sand culture to examine their Al tolerance and ability to utilize different P sources, including Ca-P, K-P, Al-P, Fe-P and phytate-P. Among the three tested genotypes, the P-efficient genotype 'TPRC2001-1' had higher Al tolerance than the P-inefficient genotype 'Fine-stem' as indicated by relative tap root length and haematoxylin staining. The three genotypes differed in their ability to utilize different P sources. The P-efficient genotype, 'TPRC2001-1', had superior ability to utilize phytate-P. The findings suggest that possible physiological mechanisms of stylo adaptation to low-P acid soils might involve superior ability of plant roots to tolerate Al toxicity and to utilize organic P and Al-P.

  9. Seltzer_et_al_2016

    EPA Pesticide Factsheets

    This dataset supports the modeling study of Seltzer et al. (2016) published in Atmospheric Environment. In this study, techniques typically used for future air quality projections are applied to a historical 11-year period to assess the performance of the modeling system when the driving meteorological conditions are obtained using dynamical downscaling of coarse-scale fields without correcting toward higher resolution observations. The Weather Research and Forecasting model and the Community Multiscale Air Quality model are used to simulate regional climate and air quality over the contiguous United States for 2000-2010. The air quality simulations for that historical period are then compared to observations from four national networks. Comparisons are drawn between defined performance metrics and other published modeling results for predicted ozone, fine particulate matter, and speciated fine particulate matter. The results indicate that the historical air quality simulations driven by dynamically downscaled meteorology are typically within defined modeling performance benchmarks and are consistent with results from other published modeling studies using finer-resolution meteorology. This indicates that the regional climate and air quality modeling framework utilized here does not introduce substantial bias, which provides confidence in the method??s use for future air quality projections.This dataset is associated with the following publication:Seltzer, K., C

  10. SmartVeh: Secure and Efficient Message Access Control and Authentication for Vehicular Cloud Computing.

    PubMed

    Huang, Qinlong; Yang, Yixian; Shi, Yuxiang

    2018-02-24

    With the growing number of vehicles and popularity of various services in vehicular cloud computing (VCC), message exchanging among vehicles under traffic conditions and in emergency situations is one of the most pressing demands, and has attracted significant attention. However, it is an important challenge to authenticate the legitimate sources of broadcast messages and achieve fine-grained message access control. In this work, we propose SmartVeh, a secure and efficient message access control and authentication scheme in VCC. A hierarchical, attribute-based encryption technique is utilized to achieve fine-grained and flexible message sharing, which ensures that vehicles whose persistent or dynamic attributes satisfy the access policies can access the broadcast message with equipped on-board units (OBUs). Message authentication is enforced by integrating an attribute-based signature, which achieves message authentication and maintains the anonymity of the vehicles. In order to reduce the computations of the OBUs in the vehicles, we outsource the heavy computations of encryption, decryption and signing to a cloud server and road-side units. The theoretical analysis and simulation results reveal that our secure and efficient scheme is suitable for VCC.

  11. Intervertebral disc detection in X-ray images using faster R-CNN.

    PubMed

    Ruhan Sa; Owens, William; Wiegand, Raymond; Studin, Mark; Capoferri, Donald; Barooha, Kenneth; Greaux, Alexander; Rattray, Robert; Hutton, Adam; Cintineo, John; Chaudhary, Vipin

    2017-07-01

    Automatic identification of specific osseous landmarks on the spinal radiograph can be used to automate calculations for correcting ligament instability and injury, which affect 75% of patients injured in motor vehicle accidents. In this work, we propose to use deep learning based object detection method as the first step towards identifying landmark points in lateral lumbar X-ray images. The significant breakthrough of deep learning technology has made it a prevailing choice for perception based applications, however, the lack of large annotated training dataset has brought challenges to utilizing the technology in medical image processing field. In this work, we propose to fine tune a deep network, Faster-RCNN, a state-of-the-art deep detection network in natural image domain, using small annotated clinical datasets. In the experiment we show that, by using only 81 lateral lumbar X-Ray training images, one can achieve much better performance compared to traditional sliding window detection method on hand crafted features. Furthermore, we fine-tuned the network using 974 training images and tested on 108 images, which achieved average precision of 0.905 with average computation time of 3 second per image, which greatly outperformed traditional methods in terms of accuracy and efficiency.

  12. Low-level information and high-level perception: the case of speech in noise.

    PubMed

    Nahum, Mor; Nelken, Israel; Ahissar, Merav

    2008-05-20

    Auditory information is processed in a fine-to-crude hierarchical scheme, from low-level acoustic information to high-level abstract representations, such as phonological labels. We now ask whether fine acoustic information, which is not retained at high levels, can still be used to extract speech from noise. Previous theories suggested either full availability of low-level information or availability that is limited by task difficulty. We propose a third alternative, based on the Reverse Hierarchy Theory (RHT), originally derived to describe the relations between the processing hierarchy and visual perception. RHT asserts that only the higher levels of the hierarchy are immediately available for perception. Direct access to low-level information requires specific conditions, and can be achieved only at the cost of concurrent comprehension. We tested the predictions of these three views in a series of experiments in which we measured the benefits from utilizing low-level binaural information for speech perception, and compared it to that predicted from a model of the early auditory system. Only auditory RHT could account for the full pattern of the results, suggesting that similar defaults and tradeoffs underlie the relations between hierarchical processing and perception in the visual and auditory modalities.

  13. SmartVeh: Secure and Efficient Message Access Control and Authentication for Vehicular Cloud Computing

    PubMed Central

    Yang, Yixian; Shi, Yuxiang

    2018-01-01

    With the growing number of vehicles and popularity of various services in vehicular cloud computing (VCC), message exchanging among vehicles under traffic conditions and in emergency situations is one of the most pressing demands, and has attracted significant attention. However, it is an important challenge to authenticate the legitimate sources of broadcast messages and achieve fine-grained message access control. In this work, we propose SmartVeh, a secure and efficient message access control and authentication scheme in VCC. A hierarchical, attribute-based encryption technique is utilized to achieve fine-grained and flexible message sharing, which ensures that vehicles whose persistent or dynamic attributes satisfy the access policies can access the broadcast message with equipped on-board units (OBUs). Message authentication is enforced by integrating an attribute-based signature, which achieves message authentication and maintains the anonymity of the vehicles. In order to reduce the computations of the OBUs in the vehicles, we outsource the heavy computations of encryption, decryption and signing to a cloud server and road-side units. The theoretical analysis and simulation results reveal that our secure and efficient scheme is suitable for VCC. PMID:29495269

  14. Characterization of the Cu(Π) and Zn(Π) binding to the Amyloid-β short peptides by both the Extended X-ray Absorption Fine Structure and the Synchrotron Radiation Circular Dichroism spectroscopy

    NASA Astrophysics Data System (ADS)

    Zhang, Zhiyin; Sun, Shuaishuai; Xu, Jianhua; Zhang, Jing; Huang, Yan; Zhang, Bingbing; Tao, Ye

    2013-04-01

    Alzheimer's disease (AD) is a progressive and devastating neurodegenerative pathology, clinically characterized by dementia, cognitive impairment, personality disorders and memory loss. It is generally accepted that, misfolding of Aβ peptides is the key element in pathogenesis and the secondary structure of Aβ can be changed to major β-strand with reasons unknown yet. Many studies have shown that the misfolding may be linked with some biometals, mainly copper and zinc ions. To characterize interactions of Aβ and metal ions, we utilized both the extended X-ray fine structure spectroscopy (EXAFS) and the synchrotron radiation circular dichroism spectroscopy (SRCD). Aβ (13-22), Aβ (13-21), Aβ (E22G) and Aβ(HH-AA) were selected to study the mechanism of copper and zinc binding to Aβ. We found that Cu interaction with H13 and H14 residues led to the disappearance of the PPΠ, while the Cu binding E22 residue caused a remarkable conformation change to β-sheet enrichment. The Zn ion, in contrast, made little effect on the conformation and it coordinated to only one histidine (H residue) or not.

  15. Fine grain separation for the production of biomass fuel from mixed municipal solid waste.

    PubMed

    Giani, H; Borchers, B; Kaufeld, S; Feil, A; Pretz, T

    2016-01-01

    The main goal of the project MARSS (Material Advanced Sustainable Systems) is to build a demonstration plant in order to recover a renewable biomass fuel suitable for the use in biomass power plants out of mixed municipal solid waste (MMSW). The demonstration plant was constructed in Mertesdorf (Germany), working alongside an existing mechanical-biological treatment plant, where the MMSW is biological dried under aerobe conditions in rotting boxes. The focus of the presented sorting campaign was set on the processing of fine grain particles minor than 11.5mm which have the highest mass content and biogenic energy potential of the utilized grain size fractions. The objective was to produce a biomass fuel with a high calorific value and a low content of fossil (plastic, synthetic) materials while maximizing the mass recovery. Therefore, the biogenic components of the dried MMSW are separated from inert and fossil components through various classification and sifting processes. In three experimental process setups of different processing depths, the grain size fraction 4-11.5mm was sifted by the use of air sifters and air tables. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Experimental and Theoretical Analysis of Sound Absorption Properties of Finely Perforated Wooden Panels

    PubMed Central

    Song, Boqi; Peng, Limin; Fu, Feng; Liu, Meihong; Zhang, Houjiang

    2016-01-01

    Perforated wooden panels are typically utilized as a resonant sound absorbing material in indoor noise control. In this paper, the absorption properties of wooden panels perforated with tiny holes of 1–3 mm diameter were studied both experimentally and theoretically. The Maa-MPP (micro perforated panels) model and the Maa-Flex model were applied to predict the absorption regularities of finely perforated wooden panels. A relative impedance comparison and full-factorial experiments were carried out to verify the feasibility of the theoretical models. The results showed that the Maa-Flex model obtained good agreement with measured results. Control experiments and measurements of dynamic mechanical properties were carried out to investigate the influence of the wood characteristics. In this study, absorption properties were enhanced by sound-induced vibration. The relationship between the dynamic mechanical properties and the panel mass-spring vibration absorption was revealed. While the absorption effects of wood porous structure were not found, they were demonstrated theoretically by using acoustic wave propagation in a simplified circular pipe with a suddenly changed cross-section model. This work provides experimental and theoretical guidance for perforation parameter design. PMID:28774063

  17. Reassessing the improbability of a muscular crinoid stem

    PubMed Central

    Gorzelak, Przemysław; Głuchowski, Edward; Salamon, Mariusz A.

    2014-01-01

    Muscular articulations in modern stalked crinoids are only present in the arms. Although it has been suggested that certain coiled-stemmed fossil taxa may have been functionally adapted to utilize muscles, evidence supporting this interpretation is lacking. Here, we use cathodoluminescence and SEM to reveal the skeletal microstructure of the enigmatic coiled-stemmed taxon Ammonicrinus (Flexibilia). Based on the well-established link between skeletal microstructure and the nature of infilling soft tissues in modern echinoderms, we reconstructed the palaeoanatomy of the Middle Devonian ammonicrinids. We show that their median columnals with elongated lateral columnal enclosure extensions (LCEE) have stereom microstructure unexpectedly resembling that in the crinoid muscular arm plates. In particular, large ligamentary facets, that are present on each side of a transverse ridge, are mainly comprised of fine galleried stereom that is indicative of the mutable collagenous tissues. In contrast, fine labyrinthic stereom, commonly associated with muscles, is situated in the periphery on each side of the surface of elongated LCEE. Our findings thus strongly suggest that the muscles may have also been present in the stem of ammonicrinids. These results reassess the previous hypotheses about evolution of muscles in crinoids and provide new insights into the mode of life of Ammonicrinus. PMID:25116414

  18. Refreshing Music: Fog Harvesting with Harps

    NASA Astrophysics Data System (ADS)

    Shi, Weiwei; Anderson, Mark; Kennedy, Brook; Boreyko, Jonathan

    2017-11-01

    Fog harvesting is a useful technique for obtaining fresh water in arid climates. The wire meshes currently utilized for fog harvesting suffer from dual constraints: coarse meshes cannot efficiently capture fog, while fine meshes suffer from clogging issues. Here, we design a new type of fog harvester comprised of an array of vertical wires, which we call ``fog harps.'' To investigate the water collection efficiency, three fog harps were designed with different diameters (254 μm, 508 μm and 1.30 mm) but the same pitch-to-diameter ratio of 2. For comparison, three different size meshes were purchased with equivalent dimensions. As expected for the mesh structures, the mid-sized wires performed the best, with a drop-off in performance for the fine or coarse meshes. In contrast, the fog harvesting rate continually increased with decreasing wire diameter for the fog harps, due to its low hysteresis that prevented droplet clogging. This resulted in a 3-fold enhancement in the fog harvesting rate for the harp form factor compared to the mesh. The lack of a performance ceiling for the harps suggest that even greater enhancements could be achieved by scaling down to yet smaller sizes.

  19. Reassessing the improbability of a muscular crinoid stem

    NASA Astrophysics Data System (ADS)

    Gorzelak, Przemysław; Głuchowski, Edward; Salamon, Mariusz A.

    2014-08-01

    Muscular articulations in modern stalked crinoids are only present in the arms. Although it has been suggested that certain coiled-stemmed fossil taxa may have been functionally adapted to utilize muscles, evidence supporting this interpretation is lacking. Here, we use cathodoluminescence and SEM to reveal the skeletal microstructure of the enigmatic coiled-stemmed taxon Ammonicrinus (Flexibilia). Based on the well-established link between skeletal microstructure and the nature of infilling soft tissues in modern echinoderms, we reconstructed the palaeoanatomy of the Middle Devonian ammonicrinids. We show that their median columnals with elongated lateral columnal enclosure extensions (LCEE) have stereom microstructure unexpectedly resembling that in the crinoid muscular arm plates. In particular, large ligamentary facets, that are present on each side of a transverse ridge, are mainly comprised of fine galleried stereom that is indicative of the mutable collagenous tissues. In contrast, fine labyrinthic stereom, commonly associated with muscles, is situated in the periphery on each side of the surface of elongated LCEE. Our findings thus strongly suggest that the muscles may have also been present in the stem of ammonicrinids. These results reassess the previous hypotheses about evolution of muscles in crinoids and provide new insights into the mode of life of Ammonicrinus.

  20. Fine tuning the color-transition temperature of thermoreversible polydiacetylene/zinc oxide nanocomposites: The effect of photopolymerization time.

    PubMed

    Traiphol, Nisanart; Faisadcha, Kunruethai; Potai, Ruttayapon; Traiphol, Rakchart

    2015-02-01

    An ability to control the thermochromic behaviors of polydiacetylene (PDA)-based materials is very important for their utilization. Recently, our group has developed the PDA/zinc oxide (ZnO) nanocomposites, which exhibit reversible thermochromism (Traiphol et al., 2011). In this study, we present our continuation work demonstrating a rather simple method for fine tuning their color-transition temperature. The PDA/ZnO nanocomposites are prepared by varying photopolymerization time, which in turn affects the length of PDA conjugated backbone. We have found that the increase of photopolymerization time from 1 to 120min results in systematically decrease of the color-transition temperature from about 85 to 40°C. These PDA/ZnO nanocomposites still exhibit reversible thermochromism. The PDA/ZnO nanocomposites embedded in polyvinyl alcohol films show two-step color-transition processes, the reversible blue to purple and then irreversible purple to orange. Interestingly, the increase of photopolymerization time causes an increase of the irreversible color-transition temperature. Our method is quite simple and cheap, which can provide a library of PDA-based materials with controllable color-transition temperature. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Development of a remote sensing algorithm to retrieve atmospheric aerosol properties using multiwavelength and multipixel information

    NASA Astrophysics Data System (ADS)

    Hashimoto, Makiko; Nakajima, Teruyuki

    2017-06-01

    We developed a satellite remote sensing algorithm to retrieve the aerosol optical properties using satellite-received radiances for multiple wavelengths and pixels. Our algorithm utilizes spatial inhomogeneity of surface reflectance to retrieve aerosol properties, and the main target is urban aerosols. This algorithm can simultaneously retrieve aerosol optical thicknesses (AOT) for fine- and coarse-mode aerosols, soot volume fraction in fine-mode aerosols (SF), and surface reflectance over heterogeneous surfaces such as urban areas that are difficult to obtain by conventional pixel-by-pixel methods. We applied this algorithm to radiances measured by the Greenhouse Gases Observing Satellite/Thermal and Near Infrared Sensor for Carbon Observations-Cloud and Aerosol Image (GOSAT/TANSO-CAI) at four wavelengths and were able to retrieve the aerosol parameters in several urban regions and other surface types. A comparison of the retrieved AOTs with those from the Aerosol Robotic Network (AERONET) indicated retrieval accuracy within ±0.077 on average. It was also found that the column-averaged SF and the aerosol single scattering albedo (SSA) underwent seasonal changes as consistent with the ground surface measurements of SSA and black carbon at Beijing, China.

  2. Summary of the Fourth AIAA CFD Drag Prediction Workshop

    NASA Technical Reports Server (NTRS)

    Vassberg, John C.; Tinoco, Edward N.; Mani, Mori; Rider, Ben; Zickuhr, Tom; Levy, David W.; Brodersen, Olaf P.; Eisfeld, Bernhard; Crippa, Simone; Wahls, Richard A.; hide

    2010-01-01

    Results from the Fourth AIAA Drag Prediction Workshop (DPW-IV) are summarized. The workshop focused on the prediction of both absolute and differential drag levels for wing-body and wing-body-horizontal-tail configurations that are representative of transonic transport air- craft. Numerical calculations are performed using industry-relevant test cases that include lift- specific flight conditions, trimmed drag polars, downwash variations, dragrises and Reynolds- number effects. Drag, lift and pitching moment predictions from numerous Reynolds-Averaged Navier-Stokes computational fluid dynamics methods are presented. Solutions are performed on structured, unstructured and hybrid grid systems. The structured-grid sets include point- matched multi-block meshes and over-set grid systems. The unstructured and hybrid grid sets are comprised of tetrahedral, pyramid, prismatic, and hexahedral elements. Effort is made to provide a high-quality and parametrically consistent family of grids for each grid type about each configuration under study. The wing-body-horizontal families are comprised of a coarse, medium and fine grid; an optional extra-fine grid augments several of the grid families. These mesh sequences are utilized to determine asymptotic grid-convergence characteristics of the solution sets, and to estimate grid-converged absolute drag levels of the wing-body-horizontal configuration using Richardson extrapolation.

  3. Formulation of boundary conditions for the multigrid acceleration of the Euler and Navier Stokes equations

    NASA Technical Reports Server (NTRS)

    Jentink, Thomas Neil; Usab, William J., Jr.

    1990-01-01

    An explicit, Multigrid algorithm was written to solve the Euler and Navier-Stokes equations with special consideration given to the coarse mesh boundary conditions. These are formulated in a manner consistent with the interior solution, utilizing forcing terms to prevent coarse-mesh truncation error from affecting the fine-mesh solution. A 4-Stage Hybrid Runge-Kutta Scheme is used to advance the solution in time, and Multigrid convergence is further enhanced by using local time-stepping and implicit residual smoothing. Details of the algorithm are presented along with a description of Jameson's standard Multigrid method and a new approach to formulating the Multigrid equations.

  4. Simulation of the influence of aerosol particles on Stokes parameters of polarized skylight

    NASA Astrophysics Data System (ADS)

    Li, L.; Li, Z. Q.; Wendisch, M.

    2014-03-01

    Microphysical properties and chemical compositions of aerosol particles determine polarized radiance distribution in the atmosphere. In this paper, the influences of different aerosol properties (particle size, shape, real and imaginary parts of refractive index) on Stokes parameters of polarized skylight in the solar principal and almucantar planes are studied by using vector radiative transfer simulations. The results show high sensitivity of the normalized Stokes parameters due to fine particle size, shape and real part of refractive index of aerosols. It is possible to utilize the strength variations at the peak positions of the normalized Stokes parameters in the principal and almucantar planes to identify aerosol types.

  5. Fiber-based free-space optical coherent receiver with vibration compensation mechanism.

    PubMed

    Zhang, Ruochi; Wang, Jianmin; Zhao, Guang; Lv, Junyi

    2013-07-29

    We propose a novel fiber-based free-space optical (FSO) coherent receiver for inter-satellite communication. The receiver takes advantage of established fiber-optic components and utilizes the fine-pointing subsystem installed in FSO terminals to minimize the influence of satellite platform vibrations. The received beam is coupled to a single-mode fiber, and the coupling efficiency of the system is investigated both analytically and experimentally. A receiving sensitivity of -38 dBm is obtained at the forward error correction limit with a transmission rate of 22.4 Gbit/s. The proposed receiver is shown to be a promising component for inter-satellite optical communication.

  6. Technologies for Decreasing Mining Losses

    NASA Astrophysics Data System (ADS)

    Valgma, Ingo; Väizene, Vivika; Kolats, Margit; Saarnak, Martin

    2013-12-01

    In case of stratified deposits like oil shale deposit in Estonia, mining losses depend on mining technologies. Current research focuses on extraction and separation possibilities of mineral resources. Selective mining, selective crushing and separation tests have been performed, showing possibilities of decreasing mining losses. Rock crushing and screening process simulations were used for optimizing rock fractions. In addition mine backfilling, fine separation, and optimized drilling and blasting have been analyzed. All tested methods show potential and depend on mineral usage. Usage in addition depends on the utilization technology. The questions like stability of the material flow and influences of the quality fluctuations to the final yield are raised.

  7. Ship detection in panchromatic images: a new method and its DSP implementation

    NASA Astrophysics Data System (ADS)

    Yao, Yuan; Jiang, Zhiguo; Zhang, Haopeng; Wang, Mengfei; Meng, Gang

    2016-03-01

    In this paper, a new ship detection method is proposed after analyzing the characteristics of panchromatic remote sensing images and ship targets. Firstly, AdaBoost(Adaptive Boosting) classifiers trained by Haar features are utilized to make coarse detection of ship targets. Then LSD (Line Segment Detector) is adopted to extract the line features in target slices to make fine detection. Experimental results on a dataset of panchromatic remote sensing images with a spatial resolution of 2m show that the proposed algorithm can achieve high detection rate and low false alarm rate. Meanwhile, the algorithm can meet the needs of practical applications on DSP (Digital Signal Processor).

  8. Apodized RFI filtering of synthetic aperture radar images

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Doerry, Armin Walter

    2014-02-01

    Fine resolution Synthetic Aperture Radar (SAR) systems necessarily require wide bandwidths that often overlap spectrum utilized by other wireless services. These other emitters pose a source of Radio Frequency Interference (RFI) to the SAR echo signals that degrades SAR image quality. Filtering, or excising, the offending spectral contaminants will mitigate the interference, but at a cost of often degrading the SAR image in other ways, notably by raising offensive sidelobe levels. This report proposes borrowing an idea from nonlinear sidelobe apodization techniques to suppress interference without the attendant increase in sidelobe levels. The simple post-processing technique is termed Apodized RFImore » Filtering (ARF).« less

  9. Friction stir weld tools having fine grain structure

    DOEpatents

    Grant, Glenn J.; Frye, John G.; Kim, Jin Yong; Lavender, Curt A.; Weil, Kenneth Scott

    2016-03-15

    Tools for friction stir welding can be made with fewer process steps, lower cost techniques, and/or lower cost ingredients than other state-of-the-art processes by utilizing improved compositions and processes of fabrication. Furthermore, the tools resulting from the improved compositions and processes of fabrication can exhibit better distribution and homogeneity of chemical constituents, greater strength, and/or increased durability. In one example, a friction stir weld tool includes tungsten and rhenium and is characterized by carbide and oxide dispersoids, by carbide particulates, and by grains that comprise a solid solution of the tungsten and rhenium. The grains do not exceed 10 micrometers in diameter.

  10. Cyclic Spin Testing of Superalloy Disks With a Dual Grain Microstructure

    NASA Technical Reports Server (NTRS)

    Gayda, John; Kantzos, Pete

    2005-01-01

    An aggressive cyclic spin test program was run to verify the reliability of superalloy disks with a dual grain structure, fine grain bore and coarse grain rim, utilizing a disk design with web holes bisecting the grain size transition zone. Results of these tests were compared with conventional disks with uniform grain structures. Analysis of the test results indicated the cyclic performance of disks with a dual grain structure could be estimated to a level of accuracy which does not appear to prohibit the use of this technology in advanced gas turbine engines, although further refinement of lifing methodology is clearly warranted.

  11. Network pharmacology: reigning in drug attrition?

    PubMed

    Alian, Osama M; Shah, Minjel; Mohammad, Momin; Mohammad, Ramzi M

    2013-06-01

    In the process of drug development, there has been an exceptionally high attrition rate in oncological compounds entering late phases of testing. This has seen a concurrent reduction in approved NCEs (new chemical entities) reaching patients. Network pharmacology has become a valuable tool in understanding the fine details of drug-target interactions as well as painting a more practical picture of phenotype relationships to patients and drugs. By utilizing all the tools achieved through molecular medicine and combining it with high throughput data analysis, interactions and mechanisms can be elucidated and treatments reasonably tailored to patients expressing specific phenotypes (or genotypes) of disease, essentially reigning in the phenomenon of drug attrition.

  12. Bacterial determinants of the social behavior of Bacillus subtilis.

    PubMed

    Romero, Diego

    2013-09-01

    Bacteria utilize sophisticated cellular machinery to sense environmental changes and coordinate the most appropriate response. Fine sensors located on cell surfaces recognize a myriad of triggers and initiate genetic cascades leading to activation or repression of certain groups of genes. Structural elements such as pilli, exopolysaccharides and flagella are also exposed at the cell surface and contribute to modulating the intimate interaction with surfaces and host cells. This review will cover the latest advances in our understanding of the biology and functionality of these bacterial determinants within the context of biofilm formation of Bacillus subtilis. Copyright © 2013 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

  13. Fluorescent nanocolloids for differential labeling of the endocytic pathway and drug delivery applications

    NASA Astrophysics Data System (ADS)

    Delehanty, James B.; Spillmann, Christopher M.; Naciri, Jawad; Algar, W. Russ; Ratna, Banahalli R.; Medintz, Igor L.

    2013-02-01

    The demonstration of fine control over nanomaterials within biological systems, particularly in live cells, is integral for the successful implementation of nanoparticles (NPs) in biomedical applications. Here, we show the ability to differentially label the endocytic pathway of mammalian cells in a spatiotemporal manner utilizing fluorescent nanocolloids (NCs) doped with a perylene-based dye. EDC-based conjugation of green- and red-emitting NCs to the iron transport protein transferrin resulted in stable bioconjugates that were efficiently endocytosed by HEK 293T/17 cells. The staggered delivery of the bioconjugates allowed for the time-resolved, differential labeling of distinct vesicular compartments along the endocytic pathway in a nontoxic manner. We further demonstrated the ability of the NCs to be impregnated with the anticancer therapeutic, doxorubicin. Delivery of the drug-doped nanoconjugates resulted in the intracellular release and nuclear accumulation of doxorubicin in a time- and dose-dependent manner. We discuss our results in the context of the utility of such materials for NP-mediated drug delivery applications.

  14. Active Detection for Exposing Intelligent Attacks in Control Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weerakkody, Sean; Ozel, Omur; Griffioen, Paul

    In this paper, we consider approaches for detecting integrity attacks carried out by intelligent and resourceful adversaries in control systems. Passive detection techniques are often incorporated to identify malicious behavior. Here, the defender utilizes finely-tuned algorithms to process information and make a binary decision, whether the system is healthy or under attack. We demonstrate that passive detection can be ineffective against adversaries with model knowledge and access to a set of input/output channels. We then propose active detection as a tool to detect attacks. In active detection, the defender leverages degrees of freedom he has in the system to detectmore » the adversary. Specifically, the defender will introduce a physical secret kept hidden from the adversary, which can be utilized to authenticate the dynamics. In this regard, we carefully review two approaches for active detection: physical watermarking at the control input, and a moving target approach for generating system dynamics. We examine practical considerations for implementing these technologies and discuss future research directions.« less

  15. Fine structure of Galactic foreground ISM towards high-redshift AGN - utilizing Herschel PACS and SPIRE data

    NASA Astrophysics Data System (ADS)

    Perger, K.; Pinter, S.; Frey, S.; Tóth, L. V.

    2018-05-01

    One of the most certain ways to determine star formation rate in galaxies is based on far infrared (FIR) measurements. To decide the origin of the observed FIR emission, subtracting the Galactic foreground is a crucial step. We utilized Herschel photometric data to determine the hydrogen column densities in three galactic latitude regions, at b = 27°, 50° and -80°. We applied a pixel-by-pixel fit to the spectral energy distribution (SED) for the images aquired from parallel PACS-SPIRE observations in all three sky areas. We determined the column densities with resolutions 45'' and 6', and compared the results with values estimated from the IRAS dust maps. Column densities at 27° and 50° galactic latitudes determined from the Herschel data are in a good agreement with the literature values. However, at the highest galactic latitude we found that the column densities from the Herschel data exceed those derived from the IRAS dust map.

  16. Towards a Switched-Capacitor Based Stimulator for Efficient Deep-Brain Stimulation

    PubMed Central

    Vidal, Jose; Ghovanloo, Maysam

    2013-01-01

    We have developed a novel 4-channel prototype stimulation circuit for implantable neurological stimulators (INS). This Switched-Capacitor based Stimulator (SCS) aims to utilize charge storage and charge injection techniques to take advantage of both the efficiency of conventional voltage-controlled stimulators (VCS) and the safety and controllability of current-controlled stimulators (CCS). The discrete SCS prototype offers fine control over stimulation parameters such as voltage, current, pulse width, frequency, and active electrode channel via a LabVIEW graphical user interface (GUI) when connected to a PC through USB. Furthermore, the prototype utilizes a floating current sensor to provide charge-balanced biphasic stimulation and ensure safety. The stimulator was analyzed using an electrode-electrolyte interface (EEI) model as well as with a pair of pacing electrodes in saline. The primary motivation of this research is to test the feasibility and functionality of a safe, effective, and power-efficient switched-capacitor based stimulator for use in Deep Brain Stimulation. PMID:21095987

  17. Platinum single-atom and cluster catalysis of the hydrogen evolution reaction

    NASA Astrophysics Data System (ADS)

    Cheng, Niancai; Stambula, Samantha; Wang, Da; Banis, Mohammad Norouzi; Liu, Jian; Riese, Adam; Xiao, Biwei; Li, Ruying; Sham, Tsun-Kong; Liu, Li-Min; Botton, Gianluigi A.; Sun, Xueliang

    2016-11-01

    Platinum-based catalysts have been considered the most effective electrocatalysts for the hydrogen evolution reaction in water splitting. However, platinum utilization in these electrocatalysts is extremely low, as the active sites are only located on the surface of the catalyst particles. Downsizing catalyst nanoparticles to single atoms is highly desirable to maximize their efficiency by utilizing nearly all platinum atoms. Here we report on a practical synthesis method to produce isolated single platinum atoms and clusters using the atomic layer deposition technique. The single platinum atom catalysts are investigated for the hydrogen evolution reaction, where they exhibit significantly enhanced catalytic activity (up to 37 times) and high stability in comparison with the state-of-the-art commercial platinum/carbon catalysts. The X-ray absorption fine structure and density functional theory analyses indicate that the partially unoccupied density of states of the platinum atoms' 5d orbitals on the nitrogen-doped graphene are responsible for the excellent performance.

  18. Stress-state effects on the stress-induced martensitic transformation of carburized 4320 steels

    NASA Astrophysics Data System (ADS)

    Karaman, I.; Balzer, M.; Sehitoglu, Huseyin; Maier, H. J.

    1998-02-01

    The effect of different stress states on the stress-induced martensitic transformation of retained austenite was investigated in carburized 4320 steels with an initial retained austenite content of 15 pct. Experiments were conducted utilizing a specialized pressure rig and comparison between stress-strain behaviors of specimens with different austenitization and tempering histories was performed under these stress states. Experimental results indicated considerable asymmetry between tension and compression, with triaxial stress states resulting in the highest strength levels for the untempered material. Fine carbide precipitates due to low-temperature tempering increased the strength and ductility of the specimens and also changed the austenite-to-martensite transformation behavior. Numerical simulations of stress-strain behaviors under different stress states were obtained, with an existing micromechanical self-consistent framework utilizing the crystallographic theory of austenite/martensite transformation and the minimum complementary free-energy principle. The model was modified for carburized steels upon microstructural investigation and predicted the same trends in effective stress-effective strain behavior as observed experimentally.

  19. Tailored nanoporous coatings fabricated on conformable polymer substrates.

    PubMed

    Poxson, David J; Mont, Frank W; Cho, Jaehee; Schubert, E Fred; Siegel, Richard W

    2012-11-01

    Nanoporous coatings have become the subject of intense investigation, in part because they have been shown to have unique and tailorable physical properties that can depart greatly from their dense or macroscopic counterparts. Nanoporous coatings are frequently fabricated utilizing oblique-angle or glancing-angle physical vapor-phase deposition techniques. However, a significant limitation for such coatings exists; they are almost always deposited on smooth and rigid planar substrates, such as silicon and glass. This limitation greatly constrains the applicability, tailorability, functionality and even the economic viability, of such nanoporous coatings. Here, we report our findings on nanoporous/polymer composite systems (NPCS) fabricated by utilizing oblique-angle electron-beam methodology. These unique composite systems exhibit several favorable characteristics, namely, (i) fine-tuned control over coating nanoporosity and thickness, (ii) excellent adhesion between the nanoporous coating and polymer substrate, (iii) the ability to withstand significant and repeated bending, and (iv) the ability to be molded conformably on two and three-dimensional surfaces while closely retaining the composite system's designed nanoporous film structure and, hence, properties.

  20. Platinum single-atom and cluster catalysis of the hydrogen evolution reaction

    PubMed Central

    Cheng, Niancai; Stambula, Samantha; Wang, Da; Banis, Mohammad Norouzi; Liu, Jian; Riese, Adam; Xiao, Biwei; Li, Ruying; Sham, Tsun-Kong; Liu, Li-Min; Botton, Gianluigi A.; Sun, Xueliang

    2016-01-01

    Platinum-based catalysts have been considered the most effective electrocatalysts for the hydrogen evolution reaction in water splitting. However, platinum utilization in these electrocatalysts is extremely low, as the active sites are only located on the surface of the catalyst particles. Downsizing catalyst nanoparticles to single atoms is highly desirable to maximize their efficiency by utilizing nearly all platinum atoms. Here we report on a practical synthesis method to produce isolated single platinum atoms and clusters using the atomic layer deposition technique. The single platinum atom catalysts are investigated for the hydrogen evolution reaction, where they exhibit significantly enhanced catalytic activity (up to 37 times) and high stability in comparison with the state-of-the-art commercial platinum/carbon catalysts. The X-ray absorption fine structure and density functional theory analyses indicate that the partially unoccupied density of states of the platinum atoms' 5d orbitals on the nitrogen-doped graphene are responsible for the excellent performance. PMID:27901129

  1. Hybrid Dispersion Laser Scanner

    PubMed Central

    Goda, K.; Mahjoubfar, A.; Wang, C.; Fard, A.; Adam, J.; Gossett, D. R.; Ayazi, A.; Sollier, E.; Malik, O.; Chen, E.; Liu, Y.; Brown, R.; Sarkhosh, N.; Di Carlo, D.; Jalali, B.

    2012-01-01

    Laser scanning technology is one of the most integral parts of today's scientific research, manufacturing, defense, and biomedicine. In many applications, high-speed scanning capability is essential for scanning a large area in a short time and multi-dimensional sensing of moving objects and dynamical processes with fine temporal resolution. Unfortunately, conventional laser scanners are often too slow, resulting in limited precision and utility. Here we present a new type of laser scanner that offers ∼1,000 times higher scan rates than conventional state-of-the-art scanners. This method employs spatial dispersion of temporally stretched broadband optical pulses onto the target, enabling inertia-free laser scans at unprecedented scan rates of nearly 100 MHz at 800 nm. To show our scanner's broad utility, we use it to demonstrate unique and previously difficult-to-achieve capabilities in imaging, surface vibrometry, and flow cytometry at a record 2D raster scan rate of more than 100 kHz with 27,000 resolvable points. PMID:22685627

  2. Action-Driven Visual Object Tracking With Deep Reinforcement Learning.

    PubMed

    Yun, Sangdoo; Choi, Jongwon; Yoo, Youngjoon; Yun, Kimin; Choi, Jin Young

    2018-06-01

    In this paper, we propose an efficient visual tracker, which directly captures a bounding box containing the target object in a video by means of sequential actions learned using deep neural networks. The proposed deep neural network to control tracking actions is pretrained using various training video sequences and fine-tuned during actual tracking for online adaptation to a change of target and background. The pretraining is done by utilizing deep reinforcement learning (RL) as well as supervised learning. The use of RL enables even partially labeled data to be successfully utilized for semisupervised learning. Through the evaluation of the object tracking benchmark data set, the proposed tracker is validated to achieve a competitive performance at three times the speed of existing deep network-based trackers. The fast version of the proposed method, which operates in real time on graphics processing unit, outperforms the state-of-the-art real-time trackers with an accuracy improvement of more than 8%.

  3. Development of nano-fabrication technique utilizing self-organizational behavior of point defects induced by ion irradiation

    NASA Astrophysics Data System (ADS)

    Nitta, Noriko; Taniwaki, Masafumi

    2006-04-01

    The present authors proposed a novel nano-fabrication technique that is able to arrange the fine cells orderly, based on their finding in GaSb implanted at a low temperature. In this article, first the experimental results that anomalous cellular structure was formed in GaSb by ion implantation is introduced and the self-organizational formation mechanism of the structure is described. Next a nano-fabrication technique that utilizes focused ion beam is described. This technique consists of two procedures, i.e. the formation process of the voids array and the development of the initial array to ordered cellular structure. Finally, the nano-fabrication is actually performed by this technique and their results are reported. Fabrication succeeded in structures where the dot (cell) interval was 100 nm or larger. The minimum ion dose for initial voids which develops to the ordered cellular structure is evaluated. It is also shown that the substrate temperature during implantation is an essential parameter for this technique.

  4. Structural Fingerprinting of Nanocrystals in the Transmission Electron Microscope

    NASA Astrophysics Data System (ADS)

    Rouvimov, Sergei; Plachinda, Pavel; Moeck, Peter

    2010-03-01

    Three novel strategies for the structurally identification of nanocrystals in a transmission electron microscope are presented. Either a single high-resolution transmission electron microscopy image [1] or a single precession electron diffractogram (PED) [2] may be employed. PEDs from fine-grained crystal powders may also be utilized. Automation of the former two strategies is in progress and shall lead to statistically significant results on ensembles of nanocrystals. Open-access databases such as the Crystallography Open Database which provides more than 81,500 crystal structure data sets [3] or its mainly inorganic and educational subsets [4] may be utilized. [1] http://www.scientificjournals.org/journals 2007/j/of/dissertation.htm [2] P. Moeck and S. Rouvimov, in: {Drugs and the Pharmaceutical Sciences}, Vol. 191, 2009, 270-313 [3] http://cod.ibt.lt, http://www.crystallography.net, http://cod.ensicaen.fr, http://nanocrystallography.org, http://nanocrystallography.net, http://journals.iucr.org/j/issues/2009/04/00/kk5039/kk5039.pdf [4] http://nanocrystallography.research.pdx.edu/CIF-searchable

  5. Potential and utilization of thermophiles and thermostable enzymes in biorefining

    PubMed Central

    Turner, Pernilla; Mamo, Gashaw; Karlsson, Eva Nordberg

    2007-01-01

    In today's world, there is an increasing trend towards the use of renewable, cheap and readily available biomass in the production of a wide variety of fine and bulk chemicals in different biorefineries. Biorefineries utilize the activities of microbial cells and their enzymes to convert biomass into target products. Many of these processes require enzymes which are operationally stable at high temperature thus allowing e.g. easy mixing, better substrate solubility, high mass transfer rate, and lowered risk of contamination. Thermophiles have often been proposed as sources of industrially relevant thermostable enzymes. Here we discuss existing and potential applications of thermophiles and thermostable enzymes with focus on conversion of carbohydrate containing raw materials. Their importance in biorefineries is explained using examples of lignocellulose and starch conversions to desired products. Strategies that enhance thermostablity of enzymes both in vivo and in vitro are also assessed. Moreover, this review deals with efforts made on developing vectors for expressing recombinant enzymes in thermophilic hosts. PMID:17359551

  6. Exposure to ultrafine particles, intracellular production of reactive oxygen species in leukocytes and altered levels of endothelial progenitor cells.

    PubMed

    Jantzen, Kim; Møller, Peter; Karottki, Dorina Gabriela; Olsen, Yulia; Bekö, Gabriel; Clausen, Geo; Hersoug, Lars-Georg; Loft, Steffen

    2016-06-01

    Exposure to particles in the fine and ultrafine size range has been linked to induction of low-grade systemic inflammation, oxidative stress and development of cardiovascular diseases. Declining levels of endothelial progenitor cells within systemic circulation have likewise been linked to progression of cardiovascular diseases. The objective was to determine if exposure to fine and ultrafine particles from indoor and outdoor sources, assessed by personal and residential indoor monitoring, is associated with altered levels of endothelial progenitor cells, and whether such effects are related to leukocyte-mediated oxidative stress. The study utilized a cross sectional design performed in 58 study participants from a larger cohort. Levels of circulating endothelial progenitor cells, defined as either late (CD34(+)KDR(+) cells) or early (CD34(+)CD133(+)KDR(+) cells) subsets were measured using polychromatic flow cytometry. We additionally measured production of reactive oxygen species in leukocyte subsets (lymphocytes, monocytes and granulocytes) by flow cytometry using intracellular 2',7'-dichlorofluoroscein. The measurements encompassed both basal levels of reactive oxygen species production and capacity for reactive oxygen species production for each leukocyte subset. We found that the late endothelial progenitor subset was negatively associated with levels of ultrafine particles measured within the participant residences and with reactive oxygen species production capacity in lymphocytes. Additionally, the early endothelial progenitor cell levels were positively associated with a personalised measure of ultrafine particle exposure and negatively associated with both basal and capacity for reactive oxygen species production in lymphocytes and granulocytes, respectively. Our results indicate that exposure to fine and ultrafine particles derived from indoor sources may have adverse effects on human vascular health. Copyright © 2016 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  7. Crystallization of high-strength nano-scale leucite glass-ceramics.

    PubMed

    Theocharopoulos, A; Chen, X; Wilson, R M; Hill, R; Cattell, M J

    2013-11-01

    Fine-grained, high strength, translucent leucite dental glass-ceramics are synthesized via controlled crystallization of finely milled glass powders. The objectives of this study were to utilize high speed planetary milling of an aluminosilicate glass for controlled surface crystallization of nano-scale leucite glass-ceramics and to test the biaxial flexural strength. An aluminosilicate glass was synthesized, attritor or planetary milled and heat-treated. Glasses and glass-ceramics were characterized using particle size analysis, X-ray diffraction and scanning electron microscopy. Experimental (fine and nanoscale) and commercial (Ceramco-3, IPS Empress Esthetic) leucite glass-ceramics were tested using the biaxial flexural strength (BFS) test. Gaussian and Weibull statistics were applied. Experimental planetary milled glass-ceramics showed an increased leucite crystal number and nano-scale median crystal sizes (0.048-0.055 μm(2)) as a result of glass particle size reduction and heat treatments. Experimental materials had significantly (p<0.05) higher mean BFS and characteristic strength values than the commercial materials. Attritor milled and planetary milled (2h) materials showed no significant (p>0.05) strength difference. All other groups' mean BFS and characteristic strengths were found to be significantly different (p<0.05) to each other. The mean (SD) MPa strengths measured were: Attritor milled: 252.4 (38.7), Planetary milled: 225.4 (41.8) [4h milling] 255.0 (35.0) [2h milling], Ceramco-3: 75.7 (6.8) and IPS Empress: 165.5 (30.6). Planetary milling enabled synthesis of nano-scale leucite glass-ceramics with high flexural strength. These materials may help to reduce problems associated with brittle fracture of all-ceramic restorations and give reduced enamel wear. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  8. Robust visual object tracking with interleaved segmentation

    NASA Astrophysics Data System (ADS)

    Abel, Peter; Kieritz, Hilke; Becker, Stefan; Arens, Michael

    2017-10-01

    In this paper we present a new approach for tracking non-rigid, deformable objects by means of merging an on-line boosting-based tracker and a fast foreground background segmentation. We extend an on-line boosting- based tracker, which uses axes-aligned bounding boxes with fixed aspect-ratio as tracking states. By constructing a confidence map from the on-line boosting-based tracker and unifying this map with a confidence map, which is obtained from a foreground background segmentation algorithm, we build a superior confidence map. For constructing a rough confidence map of a new frame based on on-line boosting, we employ the responses of the strong classifier as well as the single weak classifier responses that were built before during the updating step. This confidence map provides a rough estimation of the object's position and dimension. In order to refine this confidence map, we build a fine, pixel-wisely segmented confidence map and merge both maps together. Our segmentation method is color-histogram-based and provides a fine and fast image segmentation. By means of back-projection and the Bayes' rule, we obtain a confidence value for every pixel. The rough and the fine confidence maps are merged together by building an adaptively weighted sum of both maps. The weights are obtained by utilizing the variances of both confidence maps. Further, we apply morphological operators in the merged confidence map in order to reduce the noise. In the resulting map we estimate the object localization and dimension via continuous adaptive mean shift. Our approach provides a rotated rectangle as tracking states, which enables a more precise description of non-rigid, deformable objects than axes-aligned bounding boxes. We evaluate our tracker on the visual object tracking (VOT) benchmark dataset 2016.

  9. Extraction of Built-Up Areas Using Convolutional Neural Networks and Transfer Learning from SENTINEL-2 Satellite Images

    NASA Astrophysics Data System (ADS)

    Bramhe, V. S.; Ghosh, S. K.; Garg, P. K.

    2018-04-01

    With rapid globalization, the extent of built-up areas is continuously increasing. Extraction of features for classifying built-up areas that are more robust and abstract is a leading research topic from past many years. Although, various studies have been carried out where spatial information along with spectral features has been utilized to enhance the accuracy of classification. Still, these feature extraction techniques require a large number of user-specific parameters and generally application specific. On the other hand, recently introduced Deep Learning (DL) techniques requires less number of parameters to represent more abstract aspects of the data without any manual effort. Since, it is difficult to acquire high-resolution datasets for applications that require large scale monitoring of areas. Therefore, in this study Sentinel-2 image has been used for built-up areas extraction. In this work, pre-trained Convolutional Neural Networks (ConvNets) i.e. Inception v3 and VGGNet are employed for transfer learning. Since these networks are trained on generic images of ImageNet dataset which are having very different characteristics from satellite images. Therefore, weights of networks are fine-tuned using data derived from Sentinel-2 images. To compare the accuracies with existing shallow networks, two state of art classifiers i.e. Gaussian Support Vector Machine (SVM) and Back-Propagation Neural Network (BP-NN) are also implemented. Both SVM and BP-NN gives 84.31 % and 82.86 % overall accuracies respectively. Inception-v3 and VGGNet gives 89.43 % of overall accuracy using fine-tuned VGGNet and 92.10 % when using Inception-v3. The results indicate high accuracy of proposed fine-tuned ConvNets on a 4-channel Sentinel-2 dataset for built-up area extraction.

  10. Fine Mapping of Ur-3, a Historically Important Rust Resistance Locus in Common Bean

    PubMed Central

    Hurtado-Gonzales, Oscar P.; Valentini, Giseli; Gilio, Thiago A. S.; Martins, Alexandre M.; Song, Qijian; Pastor-Corrales, Marcial A.

    2016-01-01

    Bean rust, caused by Uromyces appendiculatus, is a devastating disease of common bean (Phaseolus vulgaris) in the Americas and Africa. The historically important Ur-3 gene confers resistance to many races of the highly variable bean rust pathogen that overcome other rust resistance genes. Existing molecular markers tagging Ur-3 for use in marker-assisted selection produce false results. Here, we describe the fine mapping of the Ur-3 locus for the development of highly accurate markers linked to Ur-3. An F2 population from the cross Pinto 114 (susceptible) × Aurora (resistant with Ur-3) was evaluated for its reaction to four different races of U. appendiculatus. A bulked segregant analysis using the SNP chip BARCBEAN6K_3 placed the approximate location of Ur-3 in the lower arm of chromosome Pv11. Specific SSR and SNP markers and haplotype analysis of 18 sequenced bean varieties positioned Ur-3 in a 46.5 kb genomic region from 46.96 to 47.01 Mb on Pv11. We discovered in this region the SS68 KASP marker that was tightly linked to Ur-3. Validation of SS68 on a panel of 130 diverse common bean cultivars containing all known rust resistance genes revealed that SS68 was highly accurate and produced no false results. The SS68 marker will be of great value in pyramiding Ur-3 with other rust resistance genes. It will also significantly reduce time and labor associated with the current phenotypic detection of Ur-3. This is the first utilization of fine mapping to discover markers linked to rust resistance in common bean. PMID:28031244

  11. Entrapped Sediments as a Source of Phosphorus in Epilithic Cyanobacterial Proliferations in Low Nutrient Rivers

    PubMed Central

    Wood, Susanna A.; Depree, Craig; Brown, Logan; McAllister, Tara; Hawes, Ian

    2015-01-01

    Proliferations of the benthic mat-forming cyanobacteria Phormidium have been reported in rivers worldwide. Phormidium commonly produces natural toxins which pose a health risk to animal and humans. Recent field studies in New Zealand identified that sites with Phormidium proliferations consistently have low concentrations of water column dissolved reactive phosphorus (DRP). Unlike other river periphyton, Phormidium mats are thick and cohesive, with water and fine sediment trapped in a mucilaginous matrix. We hypothesized that daytime photosynthetic activity would elevate pH inside the mats, and/or night time respiration would reduce dissolved oxygen. Either condition could be sufficient to facilitate desorption of phosphates from sediment incorporated within mats, thus allowing Phormidium to utilize it for growth. Using microelectrodes, optodes and pulse amplitude modulation fluorometry we demonstrated that photosynthetic activity results in elevated pH (>9) during daytime, and that night-time respiration causes oxygen depletion (<4 mg L-1) within mats. Water trapped within the mucilaginous Phormidium mat matrix had on average 320-fold higher DRP concentrations than bulk river water and this, together with elevated concentrations of elements, including iron, suggest phosphorus release from entrapped sediment. Sequential extraction of phosphorus from trapped sediment was used to investigate the role of sediment at sites on the Mangatainoka River (New Zealand) with and without Phormidium proliferations. Deposition of fine sediment (<63 μm) was significantly higher at the site with the most extensive proliferations and concentrations of biological available phosphorus were two- to four- fold higher. Collectively these results provide evidence that fine sediment can provide a source of phosphorus to support Phormidium growth and proliferation. PMID:26479491

  12. Sensitivity analyses of factors influencing CMAQ performance for fine particulate nitrate.

    PubMed

    Shimadera, Hikari; Hayami, Hiroshi; Chatani, Satoru; Morino, Yu; Mori, Yasuaki; Morikawa, Tazuko; Yamaji, Kazuyo; Ohara, Toshimasa

    2014-04-01

    Improvement of air quality models is required so that they can be utilized to design effective control strategies for fine particulate matter (PM2.5). The Community Multiscale Air Quality modeling system was applied to the Greater Tokyo Area of Japan in winter 2010 and summer 2011. The model results were compared with observed concentrations of PM2.5 sulfate (SO4(2-)), nitrate (NO3(-)) and ammonium, and gaseous nitric acid (HNO3) and ammonia (NH3). The model approximately reproduced PM2.5 SO4(2-) concentration, but clearly overestimated PM2.5 NO3(-) concentration, which was attributed to overestimation of production of ammonium nitrate (NH4NO3). This study conducted sensitivity analyses of factors associated with the model performance for PM2.5 NO3(-) concentration, including temperature and relative humidity, emission of nitrogen oxides, seasonal variation of NH3 emission, HNO3 and NH3 dry deposition velocities, and heterogeneous reaction probability of dinitrogen pentoxide. Change in NH3 emission directly affected NH3 concentration, and substantially affected NH4NO3 concentration. Higher dry deposition velocities of HNO3 and NH3 led to substantial reductions of concentrations of the gaseous species and NH4NO3. Because uncertainties in NH3 emission and dry deposition processes are probably large, these processes may be key factors for improvement of the model performance for PM2.5 NO3(-). The Community Multiscale Air Quality modeling system clearly overestimated the concentration of fine particulate nitrate in the Greater Tokyo Area of Japan, which was attributed to overestimation of production of ammonium nitrate. Sensitivity analyses were conducted for factors associated with the model performance for nitrate. Ammonia emission and dry deposition of nitric acid and ammonia may be key factors for improvement of the model performance.

  13. Fine Mapping of Ur-3, a Historically Important Rust Resistance Locus in Common Bean.

    PubMed

    Hurtado-Gonzales, Oscar P; Valentini, Giseli; Gilio, Thiago A S; Martins, Alexandre M; Song, Qijian; Pastor-Corrales, Marcial A

    2017-02-09

    Bean rust, caused by Uromyces appendiculatus , is a devastating disease of common bean ( Phaseolus vulgaris ) in the Americas and Africa. The historically important Ur-3 gene confers resistance to many races of the highly variable bean rust pathogen that overcome other rust resistance genes. Existing molecular markers tagging Ur-3 for use in marker-assisted selection produce false results. Here, we describe the fine mapping of the Ur-3 locus for the development of highly accurate markers linked to Ur-3 An F 2 population from the cross Pinto 114 (susceptible) × Aurora (resistant with Ur-3 ) was evaluated for its reaction to four different races of U. appendiculatus A bulked segregant analysis using the SNP chip BARCBEAN6K_3 placed the approximate location of Ur-3 in the lower arm of chromosome Pv11. Specific SSR and SNP markers and haplotype analysis of 18 sequenced bean varieties positioned Ur-3 in a 46.5 kb genomic region from 46.96 to 47.01 Mb on Pv11. We discovered in this region the SS68 KASP marker that was tightly linked to Ur-3 Validation of SS68 on a panel of 130 diverse common bean cultivars containing all known rust resistance genes revealed that SS68 was highly accurate and produced no false results. The SS68 marker will be of great value in pyramiding Ur-3 with other rust resistance genes. It will also significantly reduce time and labor associated with the current phenotypic detection of Ur-3 This is the first utilization of fine mapping to discover markers linked to rust resistance in common bean. Copyright © 2017 Hurtado-Gonzales et al.

  14. High-throughput Analysis of Large Microscopy Image Datasets on CPU-GPU Cluster Platforms

    PubMed Central

    Teodoro, George; Pan, Tony; Kurc, Tahsin M.; Kong, Jun; Cooper, Lee A. D.; Podhorszki, Norbert; Klasky, Scott; Saltz, Joel H.

    2014-01-01

    Analysis of large pathology image datasets offers significant opportunities for the investigation of disease morphology, but the resource requirements of analysis pipelines limit the scale of such studies. Motivated by a brain cancer study, we propose and evaluate a parallel image analysis application pipeline for high throughput computation of large datasets of high resolution pathology tissue images on distributed CPU-GPU platforms. To achieve efficient execution on these hybrid systems, we have built runtime support that allows us to express the cancer image analysis application as a hierarchical data processing pipeline. The application is implemented as a coarse-grain pipeline of stages, where each stage may be further partitioned into another pipeline of fine-grain operations. The fine-grain operations are efficiently managed and scheduled for computation on CPUs and GPUs using performance aware scheduling techniques along with several optimizations, including architecture aware process placement, data locality conscious task assignment, data prefetching, and asynchronous data copy. These optimizations are employed to maximize the utilization of the aggregate computing power of CPUs and GPUs and minimize data copy overheads. Our experimental evaluation shows that the cooperative use of CPUs and GPUs achieves significant improvements on top of GPU-only versions (up to 1.6×) and that the execution of the application as a set of fine-grain operations provides more opportunities for runtime optimizations and attains better performance than coarser-grain, monolithic implementations used in other works. An implementation of the cancer image analysis pipeline using the runtime support was able to process an image dataset consisting of 36,848 4Kx4K-pixel image tiles (about 1.8TB uncompressed) in less than 4 minutes (150 tiles/second) on 100 nodes of a state-of-the-art hybrid cluster system. PMID:25419546

  15. Balloon Borne Arc-Second Pointer Feasibility Study

    NASA Technical Reports Server (NTRS)

    Ward, Philip R.; DeWeese, Keith D.

    2003-01-01

    For many years scientists have been utilizing stratospheric balloons as low-cost platforms on which to conduct space science experiments. A major hurdle in extending the range of experiments for which these vehicles are useful has been the imposition of the gondola dynamics on the accuracy with which an instrument can be kept pointed at a celestial target. A significant number of scientists have sought the ability to point their instruments with jitter in the arc-second range. This paper presents the design and analysis of a stratospheric balloon borne pointing system that is able to meet this requirement. The foundation for a high fidelity controller simulation is presented. The flexibility of the flight train is represented through generalized modal analysis. A multiple controller scheme is introduced for coarse and fine pointing. Coarse azimuth pointing is accomplished by an established pointing system, with extensive flight history, residing above the gondola structure. A pitch-yaw gimbal mount is used for fine pointing, providing orthogonal axes when nominally on target. Fine pointing actuation is from direct drive dc motors, eliminating backlash problems. An analysis of friction nonlinearities and a demonstration of the necessity in eliminating static fiction are provided. A unique bearing hub design is introduced that eliminates static fiction from the system dynamics. A control scheme involving linear accelerometers for enhanced disturbance rejection is also presented. Results from a linear analysis of the total system and the high fidelity simulation are given. This paper establishes that the proposed control strategy can be made robustly stable with significant design margins. Also demonstrated is the efficacy of the proposed system in rejecting disturbances larger than those considered realistic. Finally, we see that sub arc-second pointing stability can be achieved for a large instrument pointing at an inertial target.

  16. Zebrafish Locomotor Responses Reveal Irritant Effects of Fine Particulate Matter Extracts and a Role for TRPA1.

    PubMed

    Stevens, Joey S; Padilla, Stephanie; DeMarini, David M; Hunter, Deborah L; Martin, W Kyle; Thompson, Leslie C; Gilmour, M Ian; Hazari, Mehdi S; Farraj, Aimen K

    2018-02-01

    Exposure to fine particulate matter (PM) air pollution causes adverse cardiopulmonary outcomes. Yet, the limited capacity to readily identify contributing PM sources and associated PM constituents in any given ambient air shed impedes risk assessment efforts. The health effects of PM have been attributed in part to its capacity to elicit irritant responses. A variety of chemicals trigger irritant behavior responses in zebrafish that can be easily measured. The purposes of this study were to examine the utility of zebrafish locomotor responses in the toxicity assessment of fine PM and its chemical fractions and uncover mechanisms of action. Locomotor responses were recorded in 6-day-old zebrafish exposed for 60 min in the dark at 26 °C to the extractable organic matter of a compressor-generated diesel exhaust PM (C-DEP) and 4 of its fractions (F1-F4) containing varying chemical classes of increasing polarity. The role of the transient receptor potential (TRP) cation channel TRPA1, a chemical sensor in mammals and zebrafish, in locomotor responses to C-DEP, was also examined. Acrolein, an environmental irritant and known activator of TRPA1, and all extracts induced concentration-dependent locomotor responses whose potencies ranked as follows: polar F3 > weakly polar F2 > C-DEP > highly polar F4 > nonpolar F1, indicating that polar and weakly polar fractions that included nitro- and oxy-polyaromatic hydrocarbons (PAHs), drove C-DEP responses. Irritant potencies in fish positively correlated with mutagenic potencies of the same extracts in strains of Salmonella sensitive to nitro- and oxy-PAHs, further implicating these chemical classes in the zebrafish responses to C-DEP. Pharmacologic inhibition of TRPA1 blocked locomotor responses to acrolein and the extracts. Taken together, these data indicate that the zebrafish locomotor assay may help expedite toxicity screening of fine PM sources, identify causal chemical classes, and uncover plausible biological mechanisms. Published by Oxford University Press on behalf of the Society of Toxicology 2017. This work is written by US Government employees and is in the public domain in the United States.

  17. Characterization of Size-Fractionated Airborne Particles Inside an Electronic Waste Recycling Facility and Acute Toxicity Testing in Mice.

    PubMed

    Kim, Yong Ho; Wyrzykowska-Ceradini, Barbara; Touati, Abderrahmane; Krantz, Q Todd; Dye, Janice A; Linak, William P; Gullett, Brian; Gilmour, M Ian

    2015-10-06

    Disposal of electronic waste (e-waste) in landfills, incinerators, or at rudimentary recycling sites can lead to the release of toxic chemicals into the environment and increased health risks. Developing e-waste recycling technologies at commercial facilities can reduce the release of toxic chemicals and efficiently recover valuable materials. While these e-waste operations represent a vast improvement over previous approaches, little is known about environmental releases, workplace exposures, and potential health impacts. In this study, airborne particulate matter (PM) was measured at various locations within a modern U.S.-based e-waste recycling facility that utilized mechanical processing. In addition, composite size fractionated PM (coarse, fine and ultrafine) samples were collected, extracted, chemically analyzed, and given by oropharyngeal aspiration to mice or cultured with lung slices for lung toxicity tests. Indoor total PM concentrations measured during the study ranged from 220 to 1200 μg/m(3). In general, the coarse PM (2.5-10 μm) was 3-4 times more abundant than fine/ultrafine PM (<2.5 μm). The coarse PM contained higher levels of Ni, Pb, and Zn (up to 6.8 times) compared to the fine (0.1-2.5 μm) and ultrafine (<0.1 μm) PM. Compared to coarse PM measurements from a regional near-roadway study, Pb and Ni were enriched 170 and 20 times, respectively, in the indoor PM, with other significant enrichments (>10 times) observed for Zn and Sb, modest enrichments (>5 times) for Cu and Sr, and minor enrichments (>2 times) for Cr, Cd, Mn, Ca, Fe, and Ba. Negligible enrichment (<2 times) or depletion (<1 time) were observed for Al, Mg, Ti, Si, and V. The coarse PM fraction elicited significant pro-inflammatory responses in the mouse lung at 24 h postexposure compared to the fine and ultrafine PM, and similar toxicity outcomes were observed in the lung slice model. We conclude that exposure to coarse PM from the facility caused substantial inflammation in the mouse lung and enrichment of these metals compared to levels normally present in the ambient PM could be of potential health concern.

  18. Anaerobic degradation of benzene in diverse anoxic environments

    USGS Publications Warehouse

    Kazumi, J.; Caldwell, M.E.; Suflita, J.M.; Lovely, D.R.; Young, L.Y.

    1997-01-01

    Benzene has often been observed to be resistant to microbial degradation under anoxic conditions. A number of recent studies, however, have demonstrated that anaerobic benzene utilization can occur. This study extends the previous reports of anaerobic benzene degradation to sediments that varied with respect to contamination input, predominant redox condition, and salinity. In spite of differences in methodology, microbial degradation of benzene was noted in slurries constructed with sediments from various geographical locations and range from aquifer sands to fine-grained estuarine muds, under methanogenic, sulfate-reducing, and iron-reducing conditions. In aquifer sediments under methanogenic conditions, benzene loss was concomitant with methane production, and microbial utilization of [14C]benzene yielded 14CO2 and 14CH4. In slurries with estuarine and aquifer sediments under sulfate-reducing conditions, the loss of sulfate in amounts consistent with the stoichiometric degradation of benzene or the conversion of [14C]benzene to 14CO2 indicates that benzene was mineralized. Benzene loss also occurred in the presence of Fe(III) in sediments from freshwater environments. Microbial benzene utilization, however, was not observed under denitrifying conditions. These results indicate that the potential for the anaerobic degradation of benzene, which was once thought to be resistant to non-oxygenase attack, exists in a variety of aquatic sediments from widely distributed locations.

  19. Comparative Investigation on Modal analysis of LM25 Aluminium alloy with other Aluminim alloys using Finite element analysis software

    NASA Astrophysics Data System (ADS)

    Arunkumar, S.; Baskaralal, V. P. M.; Muthuraman, V.

    2017-03-01

    The rudimentary steps of the modal analysis and simulation are carried out. The modal analysis is carried out on the different Aluminum Alloys cantilever beam. The cantilever beam is designed in the graphical environment of the ANSYS. The cantilever beam was fine-tuned on one end with all degree of liberation on this end were taken, beam cannot move and rotate. Mode shapes and natural frequencies are premeditated in platforms ANSYS with arithmetical formulation of the direct solver including the block Lanczos method. Aluminum alloys are widely utilized in much application due to their estimable weight to vigor property. Many examination works have been distributed out to make developments the mechanical properties of aluminum alloys. The composition of alloying elements plays a consequential role in deciding the properties of an alloy. In this study a numerical analysis implement i.e., finite element analysis (FEA) is utilized. The work obtainable in this paper is aimed at the study of effect of modal analysis of different aluminum alloys. The modeling and analysis is carried out utilizing ANSYS FEA software. A modal analysis is carried out to understand the modes of frequency demeanor of the material considered. The modal analysis play a vital role in the design of components subjected to high vibration.

  20. Remote-sensing application for facilitating land resource assessment and monitoring for utility-scale solar energy development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hamada, Yuki; Grippo, Mark A.

    2015-01-01

    A monitoring plan that incorporates regional datasets and integrates cost-effective data collection methods is necessary to sustain the long-term environmental monitoring of utility-scale solar energy development in expansive, environmentally sensitive desert environments. Using very high spatial resolution (VHSR; 15 cm) multispectral imagery collected in November 2012 and January 2014, an image processing routine was developed to characterize ephemeral streams, vegetation, and land surface in the southwestern United States where increased utility-scale solar development is anticipated. In addition to knowledge about desert landscapes, the methodology integrates existing spectral indices and transformation (e.g., visible atmospherically resistant index and principal components); a newlymore » developed index, erosion resistance index (ERI); and digital terrain and surface models, all of which were derived from a common VHSR image. The methodology identified fine-scale ephemeral streams with greater detail than the National Hydrography Dataset and accurately estimated vegetation distribution and fractional cover of various surface types. The ERI classified surface types that have a range of erosive potentials. The remote-sensing methodology could ultimately reduce uncertainty and monitoring costs for all stakeholders by providing a cost-effective monitoring approach that accurately characterizes the land resources at potential development sites.« less

  1. Fine motor skills in children with prenatal alcohol exposure or fetal alcohol spectrum disorder.

    PubMed

    Doney, Robyn; Lucas, Barbara R; Jones, Taryn; Howat, Peter; Sauer, Kay; Elliott, Elizabeth J

    2014-01-01

    Prenatal alcohol exposure (PAE) can cause fetal alcohol spectrum disorders (FASD) and associated neurodevelopmental impairments. It is uncertain which types of fine motor skills are most likely to be affected after PAE or which assessment tools are most appropriate to use in FASD diagnostic assessments. This systematic review examined which types of fine motor skills are impaired in children with PAE or FASD; which fine motor assessments are appropriate for FASD diagnosis; and whether fine motor impairments are evident at both "low" and "high" PAE levels. A systematic review of relevant databases was undertaken using key terms. Relevant studies were extracted using a standardized form, and methodological quality was rated using a critical appraisal tool. Twenty-four studies met inclusion criteria. Complex fine motor skills, such as visual-motor integration, were more frequently impaired than basic fine motor skills, such as grip strength. Assessment tools that specifically assessed fine motor skills more consistently identified impairments than those which assessed fine motor skills as part of a generalized neurodevelopmental assessment. Fine motor impairments were associated with "moderate" to "high" PAE levels. Few studies reported fine motor skills of children with "low" PAE levels, so the effect of lower PAE levels on fine motor skills remains uncertain. Comprehensive assessment of a range of fine motor skills in children with PAE is important to ensure an accurate FASD diagnosis and develop appropriate therapeutic interventions for children with PAE-related fine motor impairments.

  2. How useful is abdominal ultrasonography in dogs with diarrhoea?

    PubMed

    Mapletoft, E K; Allenspach, K; Lamb, C R

    2018-01-01

    To assess the utility of abdominal ultrasonography in the diagnostic work-up of dogs with diarrhoea. Retrospective cross-sectional study based on a referral population of dogs with diarrhoea. Associations between the clinical signs, use of abdominal ultrasonography, results of abdominal ultrasonography and subsequent work-up were examined. The utility of abdominal ultrasonography was scored as high, moderate, none or counterproductive based on review of medical records. Medical records of 269 dogs were reviewed, of which 149 (55%) had abdominal ultrasonography. The most frequent result was no ultrasonographic abnormalities affecting the intestine in 65 (44%) dogs. Ultrasonography results were associated with subsequent work-up as follows: (1) no detected abnormalities and dietary trial; (2) focal thickening of the intestinal wall, loss of intestinal wall layers or enlarged abdominal lymph nodes and ultrasound-guided fine-needle aspirates; (3) diffuse thickening of the intestinal wall or hyperechoic striations in the small intestinal mucosa and endoscopy; and (4) small intestinal foreign body and coeliotomy. Abdominal ultrasonography was considered to be diagnostic without further testing in only four (3%) dogs: two had a portosystemic shunt identified ultrasonographically, one had a linear foreign body and one had a perforated pyloric ulcer. Abdominal ultrasonography had moderate utility in 56 (38%) dogs and no utility in 79 (53%) dogs. Abdominal ultrasonography was considered counterproductive in 10 (7%) dogs because results were either falsely negative or falsely positive. These results should prompt clinicians to reconsider routine use of abdominal ultrasonography in dogs with diarrhoea. © 2017 British Small Animal Veterinary Association.

  3. Automated recognition of microcalcification clusters in mammograms

    NASA Astrophysics Data System (ADS)

    Bankman, Isaac N.; Christens-Barry, William A.; Kim, Dong W.; Weinberg, Irving N.; Gatewood, Olga B.; Brody, William R.

    1993-07-01

    The widespread and increasing use of mammographic screening for early breast cancer detection is placing a significant strain on clinical radiologists. Large numbers of radiographic films have to be visually interpreted in fine detail to determine the subtle hallmarks of cancer that may be present. We developed an algorithm for detecting microcalcification clusters, the most common and useful signs of early, potentially curable breast cancer. We describe this algorithm, which utilizes contour map representations of digitized mammographic films, and discuss its benefits in overcoming difficulties often encountered in algorithmic approaches to radiographic image processing. We present experimental analyses of mammographic films employing this contour-based algorithm and discuss practical issues relevant to its use in an automated film interpretation instrument.

  4. Bubble Point Measurements with Liquid Methane of a Screen Channel Capillary Liquid Acquisition Device

    NASA Technical Reports Server (NTRS)

    Jurns, John M.; McQuillen, John B.; Gaby, Joseph D., Jr.; Sinacore, Steven A., Jr.

    2009-01-01

    Liquid acquisition devices (LADs) can be utilized within a propellant tank in space to deliver single-phase liquid to the engine in low gravity. One type of liquid acquisition device is a screened gallery whereby a fine mesh screen acts as a 'bubble filter' and prevents the gas bubbles from passing through until a crucial pressure differential condition across the screen, called the bubble point, is reached. This paper presents data for LAD bubble point data in liquid methane (LCH4) for stainless steel Dutch twill screens with mesh sizes of 325 by 2300. These tests represent the first known nonproprietary effort to collect bubble point data for LCH4.

  5. Protein Engineering Towards Natural Product Synthesis and Diversification

    PubMed Central

    Zabala, Angelica O.; Cacho, Ralph A.; Tang, Yi

    2014-01-01

    A dazzling array of enzymes is used by nature in making structurally complex natural products. These enzymes constitute a molecular toolbox that may be used in the construction and fine-tuning of pharmaceutically active molecules. Aided by technological advancements in protein engineering, it is now possible to tailor the activities and specificities of these enzymes as biocatalysts in the production of both natural products and their unnatural derivatives. These efforts are crucial in drug discovery and development, where there is a continuous quest for more potent agents. Both rational and random evolution techniques have been utilized in engineering these enzymes. This review will highlight some examples from several large families of natural products. PMID:22006344

  6. Utilization of Ancillary Studies in the Cytologic Diagnosis of Respiratory Lesions

    PubMed Central

    Layfield, Lester J.; Roy-Chowdhuri, Sinchita; Baloch, Zubair; Ehya, Hormoz; Geisinger, Kim; Hsiao, Susan J.; Lin, Oscar; Lindeman, Neal I.; Roh, Michael; Schmitt, Fernando; Sidiropoulos, Nikoletta; VanderLaan, Paul A.

    2017-01-01

    The Papanicolaou Society of Cytopathology has developed a set of guidelines for respiratory cytology including indications for sputum examination, bronchial washings and brushings, CT-guided FNA and endobronchial ultrasound guided fine needle aspiration (EBUS-FNA), as well as recommendations for classification and criteria, ancillary testing and post-cytologic diagnosis management and follow-up. All recommendation documents are based on the expertise of committee members, an extensive literature review, and feedback from presentations at national and international conferences. The guideline documents selectively present the results of these discussions. The present document summarizes recommendations for ancillary testing of cytologic samples. Ancillary testing including microbiologic, immunocytochemical, flow cytometric, and molecular testing, including next-generation sequencing are discussed. PMID:27561242

  7. Emulator-assisted data assimilation in complex models

    NASA Astrophysics Data System (ADS)

    Margvelashvili, Nugzar Yu; Herzfeld, Mike; Rizwi, Farhan; Mongin, Mathieu; Baird, Mark E.; Jones, Emlyn; Schaffelke, Britta; King, Edward; Schroeder, Thomas

    2016-09-01

    Emulators are surrogates of complex models that run orders of magnitude faster than the original model. The utility of emulators for the data assimilation into ocean models is still not well understood. High complexity of ocean models translates into high uncertainty of the corresponding emulators which may undermine the quality of the assimilation schemes based on such emulators. Numerical experiments with a chaotic Lorenz-95 model are conducted to illustrate this point and suggest a strategy to alleviate this problem through the localization of the emulation and data assimilation procedures. Insights gained through these experiments are used to design and implement data assimilation scenario for a 3D fine-resolution sediment transport model of the Great Barrier Reef (GBR), Australia.

  8. Spectral characterization of forest damage occurring on Whiteface Mountain, NY - Studies with the Fluorescence Line Imager (FLI) and ground-based spectrometers

    NASA Technical Reports Server (NTRS)

    Rock, B. N.; Moss, D. M.; Miller, J. R.; Freemantle, J. R.; Boyer, M. G.

    1990-01-01

    Ground-based spectral characteristics of fir wave damage and an analysis of calibrated FLI data acquired along the same fir wave utilized for the in situ measurements are presented. Derivative curve data were produced from both in situ and FLI reflectance measurements for the red edge spectral region for birch and for various portions of a fir wave. The results suggested that with proper atmospheric correction of airborne imaging spectrometer data sets, the derivative curve approach will provide an accurate means of assessing red edge parameters, and that such data will permit identification of specific types of forest damage on the basis of spectral fine features.

  9. Promise and pitfalls of molecular markers of thyroid nodules

    PubMed Central

    Jadhav, S.; Lila, Anurag; Bandgar, Tushar; Shah, Nalini

    2012-01-01

    Thyroid nodules are common in the general population with a prevalence of 5-7% The initial evaluation of thyroid nodules commonly involves thyroid function tests, an ultrasound (USG) and fine needle aspiration biopsy (FNAB). The optimal management of patients with thyroid nodules with indeterminate cytology is plagued by the lack of highly sensitive and specific diagnostic modalities In this article we attempt to review the available literature on the molecular markers which are increasingly being studied for their diagnostic utility in assessing thyroid nodules. The various molecular markers consist of gene mutations, gene re arrangements, RNA based assays and immunohistochemical markers. The molecular markers definitely would help to optimise the management of such patients. PMID:23565369

  10. Meningioma presenting as temporal region swelling: Diagnosis by cytopathology and immunohistochemical confirmation on cell block preparation

    PubMed Central

    Nair, Anila Kunjulekshmi Amma Raveendran; Nayak, Nileena; Kattoor, Jayasree

    2015-01-01

    Meningiomas are common intracranial neoplasms. Meningomas are rarely subjected to fine-needle aspiration (FNA) studies. However, intraoperative squash preparations are commonly done. FNA of meningiomas are usually performed incidentally for cases with a clinical suspicion of some other disease such as metastatic carcinoma. We are reporting two cases, which were referred to our center with a diagnosis of metastatic carcinoma on FNA from swelling of the temporal region. We are discussing the characteristic cytomorphological features, which help in diagnosing meningiomas, the common cytological differentials, and the utility of immunohistochemistry (IHC) on cell block preparations in confirming the diagnosis, especially when there is a clinical differential diagnosis. PMID:26729986

  11. Depth-resolved fluorescence of biological tissue

    NASA Astrophysics Data System (ADS)

    Wu, Yicong; Xi, Peng; Cheung, Tak-Hong; Yim, So Fan; Yu, Mei-Yung; Qu, Jianan Y.

    2005-06-01

    The depth-resolved autofluorescence ofrabbit oral tissue, normal and dysplastic human ectocervical tissue within l20μm depth were investigated utilizing a confocal fluorescence spectroscopy with the excitations at 355nm and 457nm. From the topmost keratinizing layer of oral and ectocervical tissue, strong keratin fluorescence with the spectral characteristics similar to collagen was observed. The fluorescence signal from epithelial tissue between the keratinizing layer and stroma can be well resolved. Furthermore, NADH and FADfluorescence measured from the underlying non-keratinizing epithelial layer were strongly correlated to the tissue pathology. This study demonstrates that the depth-resolved fluorescence spectroscopy can reveal fine structural information on epithelial tissue and potentially provide more accurate diagnostic information for determining tissue pathology.

  12. Utilization of ERTS-1 data to monitor and classify eutrophication of inland lakes

    NASA Technical Reports Server (NTRS)

    Chase, P. E. (Principal Investigator)

    1973-01-01

    The author has identified the following significant results. Bands 6 and 7 have fine structure as obtained by proper selection of digital levels in processing the CCT's. This is contrary to the imagery density received. This means that the small lakes can be classified in IR for different types of water masses. At least four distinct water masses have been determined for test lakes. They are shoreline, shallow water, and two deep waters. One deep water is patchy and presents difficulty in training set selection. The excellent weather and a completely successful field test form a significant happening. It required 12 orbits over the test area before perfect weather occurred.

  13. A Privacy Access Control Framework for Web Services Collaboration with Role Mechanisms

    NASA Astrophysics Data System (ADS)

    Liu, Linyuan; Huang, Zhiqiu; Zhu, Haibin

    With the popularity of Internet technology, web services are becoming the most promising paradigm for distributed computing. This increased use of web services has meant that more and more personal information of consumers is being shared with web service providers, leading to the need to guarantee the privacy of consumers. This paper proposes a role-based privacy access control framework for Web services collaboration, it utilizes roles to specify the privacy privileges of services, and considers the impact on the reputation degree of the historic experience of services in playing roles. Comparing to the traditional privacy access control approaches, this framework can make the fine-grained authorization decision, thus efficiently protecting consumers' privacy.

  14. Diagnosis of Infectious Diseases: a Cytopathologist’s Perspective

    PubMed Central

    Powers, Celeste N.

    1998-01-01

    This review explores the role of the cytopathology laboratory in the detection and presumptive identification of microorganisms. Sample procurement by exfoliation, abrasion, and aspiration techniques, as well as a variety of cytopreparatory and staining methods, is reviewed. Emphasis is placed on the utility of fine-needle aspiration as a rapid, safe, and cost-effective diagnositic procedure. The role of rapid interpretation and specimen triage is also discussed. Cytomorphologic features and staining characteristics are presented for a spectrum of microorganisms potentially encountered in the cytopathology laboratory. Pitfalls in diagnosis and the usefulness of special stains and ancillary techniques are also evaluated. The importance of communication, collaboration, and clinical correlation is stressed. PMID:9564567

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Lingda; Hayes, Ari; Song, Shuaiwen

    Modern GPUs employ cache to improve memory system efficiency. However, large amount of cache space is underutilized due to irregular memory accesses and poor spatial locality which exhibited commonly in GPU applications. Our experiments show that using smaller cache lines could improve cache space utilization, but it also frequently suffers from significant performance loss by introducing large amount of extra cache requests. In this work, we propose a novel cache design named tag-split cache (TSC) that enables fine-grained cache storage to address the problem of cache space underutilization while keeping memory request number unchanged. TSC divides tag into two partsmore » to reduce storage overhead, and it supports multiple cache line replacement in one cycle.« less

  16. Static facial expression recognition with convolution neural networks

    NASA Astrophysics Data System (ADS)

    Zhang, Feng; Chen, Zhong; Ouyang, Chao; Zhang, Yifei

    2018-03-01

    Facial expression recognition is a currently active research topic in the fields of computer vision, pattern recognition and artificial intelligence. In this paper, we have developed a convolutional neural networks (CNN) for classifying human emotions from static facial expression into one of the seven facial emotion categories. We pre-train our CNN model on the combined FER2013 dataset formed by train, validation and test set and fine-tune on the extended Cohn-Kanade database. In order to reduce the overfitting of the models, we utilized different techniques including dropout and batch normalization in addition to data augmentation. According to the experimental result, our CNN model has excellent classification performance and robustness for facial expression recognition.

  17. Dispersal of fine sediment in nearshore coastal waters

    USGS Publications Warehouse

    Warrick, Jonathan A.

    2013-01-01

    Fine sediment (silt and clay) plays an important role in the physical, ecological, and environmental conditions of coastal systems, yet little is known about the dispersal and fate of fine sediment across coastal margin settings outside of river mouths. Here I provide simple physical scaling and detailed monitoring of a beach nourishment project near Imperial Beach, California, with a high portion of fines (40% silt and clay by weight). These results provide insights into the pathways and residence times of fine sediment transport across a wave-dominated coastal margin. Monitoring of the project used physical, optical, acoustic, and remote sensing techniques to track the fine portion of the nourishment sediment. The initial transport of fine sediment from the beach was influenced strongly by longshore currents of the surf zone that were established in response to the approach angles of the waves. The mean residence time of fine sediment in the surf zone—once it was suspended—was approximately 1 hour, and rapid decreases in surf zone fine sediment concentrations along the beach resulted from mixing and offshore transport in turbid rip heads. For example, during a day with oblique wave directions and surf zone longshore currents of approximately 25 cm/s, the offshore losses of fine sediment in rips resulted in a 95% reduction in alongshore surf zone fine sediment flux within 1 km of the nourishment site. However, because of the direct placement of nourishment sediment on the beach, fine suspended-sediment concentrations in the swash zone remained elevated for several days after nourishment, while fine sediment was winnowed from the beach. Once offshore of the surf zone, fine sediment settled downward in the water column and was observed to transport along and across the inner shelf. Vertically sheared currents influenced the directions and rates of fine sediment transport on the shelf. Sedimentation of fine sediment was greatest on the seafloor directly offshore of the nourishment site. However, a mass balance of sediment suggests that the majority of the fine sediment moved far away (over 2 km) from the nourishment site or to water depths greater than 10 m, where fine sediment represents a substantial portion of the bed material. Thus, the fate of fine sediment in nearshore waters was influenced strongly by wave conditions, surf zone and rip current transport, and the vertical density and flow conditions of coastal waters.

  18. Dispersibility of lactose fines as compared to API in dry powders for inhalation.

    PubMed

    Thalberg, Kyrre; Åslund, Simon; Skogevall, Marcus; Andersson, Patrik

    2016-05-17

    This work investigates the dispersion performance of fine lactose particles as function of processing time, and compares it to the API, using Beclomethasone Dipropionate (BDP) as model API. The total load of fine particles is kept constant in the formulations while the proportions of API and lactose fines are varied. Fine particle assessment demonstrates that the lactose fines have higher dispersibility than the API. For standard formulations, processing time has a limited effect on the Fine Particle Fraction (FPF). For formulations containing magnesium stearate (MgSt), FPF of BDP is heavily influenced by processing time, with an initial increase, followed by a decrease at longer mixing times. An equation modeling the observed behavior is presented. Surprisingly, the dispersibility of the lactose fines present in the same formulation remains unaffected by mixing time. Magnesium analysis demonstrates that MgSt is transferred to the fine particles during the mixing process, thus lubrication both BDP and lactose fines, which leads to an increased FPF. Dry particle sizing of the formulations reveals a loss of fine particles at longer mixing times. Incorporation of fine particles into the carrier surfaces is believed to be behind this, and is hence a mechanism of importance as regards the dispersion performance of dry powders for inhalation. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. 7 CFR 400.454 - Disqualification and civil fines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Disqualification and civil fines. 400.454 Section 400...-Compliance § 400.454 Disqualification and civil fines. (a) Before any disqualification or civil fine is.... (3) Disqualification and civil fines may only be imposed if a preponderance of the evidence shows...

  20. Technical Advances in Endoscopic Ultrasound (EUS)-Guided Tissue Acquisition for Pancreatic Cancers: How Can We Get the Best Results with EUS-Guided Fine Needle Aspiration?

    PubMed Central

    Kedia, Prashant; Gaidhane, Monica

    2013-01-01

    Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is one of the least invasive and most effective modality in diagnosing pancreatic adenocarcinoma in solid pancreatic lesions, with a higher diagnostic accuracy than cystic tumors. EUS-FNA has been shown to detect tumors less than 3 mm, due to high spatial resolution allowing the detection of very small lesions and vascular invasion, particularly in the pancreatic head and neck, which may not be detected on transverse computed tomography. Furthermore, this minimally invasive procedure is often ideal in the endoscopic procurement of tissue in patients with unresectable tumors. While EUS-FNA has been increasingly used as a diagnostic tool, most studies have collectively looked at all primary pancreatic solid lesions, including lymphomas and pancreatic neuroendocrine neoplasms, whereas very few studies have examined the diagnostic utility of EUS-FNA of pancreatic ductal carcinoma only. As with any novel and advanced endoscopic procedure that may incorporate several practices and approaches, endoscopists have adopted diverse techniques to improve the tissue procurement practice and increase diagnostic accuracy. In this article, we present a review of literature to date and discuss currently practiced EUS-FNA technique, including indications, technical details, equipment, patient selection, and diagnostic accuracy. PMID:24143320

  1. Repeat Endoscopic Ultrasound-Guided Fine-Needle Aspiration in Patients with Suspected Pancreatic Cancer: Diagnostic Yield and Associated Change in Access to Appropriate Care

    PubMed Central

    Stanger, Dylan; Shuster, Constantin; Telford, Jennifer; Lam, Eric

    2016-01-01

    Background. There is a high incidence of inconclusive cytopathology at initial EUS-FNA (endoscopic ultrasound-guided fine-needle aspiration) for suspected malignant pancreatic lesions. To obtain appropriate preoperative or palliative chemotherapy for pancreatic cancer, definitive cytopathology is often required. The utility of repeat EUS-FNA is not well established. Methods. A retrospective cohort study was conducted evaluating the yield of repeat EUS-FNA in determining a cytological diagnosis in patients who had undergone a prior EUS-FNA for diagnosis of suspected malignant pancreatic lesions with inconclusive cytopathology. The wait times to the second procedure and to decisions regarding therapy were calculated. Results. Overall, 45 repeat EUS-FNA procedures were performed over seven years for suspected malignant pancreatic lesions. Cytopathological class (I to IV) changed between first and second EUS-FNA in 32 patients (71%). Of 34 patients with an initially nonconclusive diagnosis, 20 had a conclusive diagnosis (59%) on repeat EUS-FNA. The cumulative yield after repeat EUS-FNA for definite pancreatic adenocarcinoma was 7 (16%). The median time interval between first and second EUS-FNA was 31 (7–175) days. Conclusions. A substantial number of patients had a definitive diagnosis of adenocarcinoma on repeat FNA and were, therefore, subsequently able to access appropriate care. PMID:27648440

  2. Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Diagnosis of Pancreatic and Peripancreatic Lesions: A Single Center Experience in Korea

    PubMed Central

    Hwang, Chang Yun; Song, Tae Jun; Moon, Sung-Hoon; Lee, Don; Park, Do Hyun; Seo, Dong Wan; Lee, Sung Koo; Kim, Myung-Hwan

    2009-01-01

    Background/Aims Although endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use has been increasing in Korea, there have not been many reports about its performance. The aim of this study was to assess the utility of EUS-FNA without on-site cytopathologist in establishing the diagnosis of solid pancreatic and peripancreatic masses from a single institution in Korea. Methods Medical records of 139 patients who underwent EUS-FNA for pancreatic and peripancreatic solid mass in the year 2007, were retrospectively reviewed. By comparing cytopathologic diagnosis of FNA with final diagnosis, sensitivity, specificity, and accuracy were determined, and factors influencing the accuracy as well as complications were analyzed. Results One hundred twenty out of 139 cases had final diagnosis of malignancy. Sensitivity, specificity, and accuracy of EUS-FNA were 82%, 89%, and 83%, respectively, and positive and negative predictive values were 100% and 46%, respectively. As for factors influencing the accuracy of FNA, lesion size was marginally significant (p-value 0.08) by multivariate analysis. Conclusions EUS-FNA performed without on-site cytopathologist was found to be accurate and safe, and thus EUS-FNA should be a part of the standard management algorithm for pancreatic and peripancreatic mass. PMID:20431733

  3. Exploring the entanglement of personal epistemologies and emotions in students' thinking

    NASA Astrophysics Data System (ADS)

    Gupta, Ayush; Elby, Andrew; Danielak, Brian A.

    2018-06-01

    Evidence from psychology, cognitive science, and neuroscience suggests that cognition and emotions are coupled. Education researchers have also documented correlations between emotions (such as joy, anxiety, fear, curiosity, boredom) and academic performance. Nonetheless, most research on students' reasoning and conceptual change within the learning sciences and physics and science education research has not attended to the role of learners' emotions in describing or modeling the fine timescale dynamics of their conceptual reasoning. The few studies that integrate emotions into models of learners' cognition have mostly done so at a coarse grain size. In this study, toward the long-term goal of incorporating emotions into models of in-the-moment cognitive dynamics, we present a case study of Judy, an undergraduate electrical engineering and physics major. We show that shifts in the intensity of a fine-grained aspect of Judy's emotions, her annoyance at conceptual homework problems, co-occur with shifts in her epistemological stance toward differentiating knowledge about and the practical utility of real circuits and idealized circuit models. We then argue for the plausibility of a cognitive model in which Judy's emotions and epistemological stances mutually affect each other. We end with discussions on how models of learners' cognition that incorporate their emotions are generative for instructional purposes and research on learning.

  4. Quantification of VOC emissions from paint spraying on a construction site using solid phase microextraction devices.

    PubMed

    Cheng, Wen-Hsi; Huang, Hsiao-Lin; Chen, Kang-Shin; Chang, Yu-Jen

    2017-10-15

    The objective of this study was to measure the emission of, and personal exposure to workers, volatile organic compound (VOC) during paint spraying on a construction site. Needle trap samplers (NTSs), which are a green solid phase microextraction sampling technology, were used to obtain air samples at a large music exhibition center. The standard active sampling method using charcoal tubes and a personal air pump, Method 1501, was simultaneously utilized at the sampling sites to assess the workers' VOC exposures. Analysis of the data thus obtained showed that benzene, toluene, ethylenebenzene, and xylenes (BTEXs) were the main emission compounds. Acetone and isobutyl alcohol, which are used as thinning solvents, were detected as minor emission compounds. The emitted concentrations of most compounds were lower than the legal emission limits in Taiwan except that of benzene, for which the 2-ppm time weighted average short-term exposure limit was exceeded. The packed divinylbenzene (DVB) in the NTS was observed under an environmental scanning electron microscope, and many fine aerosols were found to be deposited on the surface of the DVB adsorbents, causing VOC extraction efficiencies after the fifth sampling in the field to decline. Workers on construction sites should be protected from emissions of VOC and fine particulates to preserve their occupational health.

  5. Cytopathologist-performed and ultrasound-guided fine needle aspiration cytology enhances diagnostic accuracy and avoids pitfalls: An overview of 20 years of personal experience with a selection of didactic cases.

    PubMed

    Paksoy, Nadir; Ozbek, Busra

    2018-01-01

    Over the last few decades, fine needle aspiration cytology (FNA) has emerged as a SAFE (Simple, Accurate, Fast, Economical) diagnostic tool based on the morphologic evaluation of cells. The first and most important step in obtaining accurate results from FNA is to procure sufficient and representative material from the lesion and to appropriately transfer this material to the laboratory. Unfortunately, the most important aspect of this task occurs beyond the control of the cytopathologist, a key reason for obtaining unsatisfactory results with FNA. There is growing interest in the field of cytology in "cytopathologist-performed ultrasound (US)-guided FNA," which has been reported to yield accurate results. The first author has been applying FNA in his own private cytopathology practice with a radiologist and under the guidance of US for more than 20 years. This study retrospectively reviews the utility of this practice. We present a selection of didactic examples under different headings that highlight the application of FNA by a cytopathologist, accompanied by US, under the guidance of a radiologist, in the form of an "outpatient FNA clinic." The use of this technique enhances diagnostic accuracy and prevents pitfalls. The highlights of each case are also outlined as "take-home messages."

  6. A geochronologic framework for the Ziegler Reservoir fossil site, Snowmass Village, Colorado

    USGS Publications Warehouse

    Mahan, Shannon; Gray, Harrison J.; Pigati, Jeffrey S.; Wilson, Jim; Lifton, Nathaniel A.; Paces, James B.; Blaauw, Maarten

    2014-01-01

    The Ziegler Reservoir fossil site near Snowmass Village, Colorado, provides a unique opportunity to reconstruct high-altitude paleoenvironmental conditions in the Rocky Mountains during the last interglacial period. We used four different techniques to establish a chronological framework for the site. Radiocarbon dating of lake organics, bone collagen, and shell carbonate, and in situ cosmogenic 10Be and 26Al ages on a boulder on the crest of a moraine that impounded the lake suggest that the ages of the sediments that hosted the fossils are between ~ 140 ka and > 45 ka. Uranium-series ages of vertebrate remains generally fall within these bounds, but extremely low uranium concentrations and evidence of open-system behavior limit their utility. Optically stimulated luminescence (OSL) ages (n = 18) obtained from fine-grained quartz maintain stratigraphic order, were replicable, and provide reliable ages for the lake sediments. Analysis of the equivalent dose (DE) dispersion of the OSL samples showed that the sediments were fully bleached prior to deposition and low scatter suggests that eolian processes were likely the dominant transport mechanism for fine-grained sediments into the lake. The resulting ages show that the fossil-bearing sediments span the latest part of marine isotope stage (MIS) 6, all of MIS 5 and MIS 4, and the earliest part of MIS 3.

  7. Evaluation of the Effects of Crushed and Expanded Waste Glass Aggregates on the Material Properties of Lightweight Concrete Using Image-Based Approaches

    PubMed Central

    Abd Elrahman, Mohamed; Sikora, Pawel; Rucinska, Teresa; Horszczaruk, Elzbieta

    2017-01-01

    Recently, the recycling of waste glass has become a worldwide issue in the reduction of waste and energy consumption. Waste glass can be utilized in construction materials, and understanding its effects on material properties is crucial in developing advanced materials. In this study, recycled crushed and expanded glasses are used as lightweight aggregates for concrete, and their relation to the material characteristics and properties is investigated using several approaches. Lightweight concrete specimens containing only crushed and expanded waste glass as fine aggregates are produced, and their pore and structural characteristics are examined using image-based methods, such as scanning electron microscopy (SEM), X-ray computed tomography (CT), and automated image analysis (RapidAir). The thermal properties of the materials are measured using both Hot Disk and ISOMET devices to enhance measurement accuracy. Mechanical properties are also evaluated, and the correlation between material characteristics and properties is evaluated. As a control group, a concrete specimen with natural fine sand is prepared, and its characteristics are compared with those of the specimens containing crushed and expanded waste glass aggregates. The obtained results support the usability of crushed and expanded waste glass aggregates as alternative lightweight aggregates. PMID:29186854

  8. Wet-milling transgenic maize seed for fraction enrichment of recombinant subunit vaccine.

    PubMed

    Moeller, Lorena; Taylor-Vokes, Raye; Fox, Steve; Gan, Qinglei; Johnson, Lawrence; Wang, Kan

    2010-01-01

    The production of recombinant proteins in plants continues to be of great interest for prospective large-scale manufacturing of industrial enzymes, nutrition products, and vaccines. This work describes fractionation by wet-milling of transgenic maize expressing the B subunit of the heat-labile enterotoxin of Escherichia coli (LT-B), a potent immunogen and candidate for oral vaccine and vaccine components. The LT-B gene was directed to express in seed by an endosperm specific promoter. Two steeping treatments, traditional steeping (TS, 0.2% SO(2) + 0.5% lactic acid) and water steeping (WS, water only), were evaluated to determine effects on recovery of functional LT-B in wet-milled fractions. The overall recovery of the LT-B protein from WS treatment was 1.5-fold greater than that from TS treatment. In both steeping types, LT-B was distributed similarly among the fractions, resulting in enrichment of functional LT-B in fine fiber, coarse fiber and pericarp fractions by concentration factors of 1.5 to 8 relative to the whole kernels on a per-mass basis. Combined with endosperm-specific expression and secretory pathway targeting, wet-milling enables enrichment of high-value recombinant proteins in low-value fractions, such as the fine fiber, and co-utilization of remaining fractions in alternative industrial applications.

  9. Interphase cytogenetics of prostatic carcinoma in fine needle aspirate smears of radical prostatectomy specimens: A practical screening tool?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, R.Y.; Troncoso, P.; El-Naggar, A.K.

    1994-09-01

    Identification of chromosomal aberrations that may be used for diagnostic or prognostic evaluation of prostatic adenocarcinoma has been the subject of great interest. In a previous study, we applied the fluorescence in situ hybridization (FISH) method on paraffin-embedded material to show that trisomy 7 was associated with the progression of human prostate cancer. In this study, we attempted to assess the utility of the FISH technique in detecting aneuploidy in fine needle aspirate (FNA) smears of prostatic tissues and to compare FISH results with that of DNA flow cytometry (FCM). Paired samples of normal and tumor FNA smears were obtainedmore » from 10 radical prostatectomy specimens. Dual-color chromosomes 7 and 9-specific centromeric DNA probes were used for FISH. FISH analysis demonstrated increased frequencies of trisomy 7 cells in all 10 tumors studied when compared with the paired normals. In contrast, 6 of 10 tumors were determined to be diploid by FCM. Our results show that FNA of radical prostatectomy specimens is a practical method for obtaining suitable material for both FISH and FCM analyses of prostate carcinoma. Thus, interphase FISH may be a practical screening tool to determine aneuploidy in FNA smears of prostatic carcinoma.« less

  10. DESDynI Quad First Stage Processor - A Four Channel Digitizer and Digital Beam Forming Processor

    NASA Technical Reports Server (NTRS)

    Chuang, Chung-Lun; Shaffer, Scott; Smythe, Robert; Niamsuwan, Noppasin; Li, Samuel; Liao, Eric; Lim, Chester; Morfopolous, Arin; Veilleux, Louise

    2013-01-01

    The proposed Deformation, Eco-Systems, and Dynamics of Ice Radar (DESDynI-R) L-band SAR instrument employs multiple digital channels to optimize resolution while keeping a large swath on a single pass. High-speed digitization with very fine synchronization and digital beam forming are necessary in order to facilitate this new technique. The Quad First Stage Processor (qFSP) was developed to achieve both the processing performance as well as the digitizing fidelity in order to accomplish this sweeping SAR technique. The qFSP utilizes high precision and high-speed analog to digital converters (ADCs), each with a finely adjustable clock distribution network to digitize the channels at the fidelity necessary to allow for digital beam forming. The Xilinx produced FX130T Virtex 5 part handles the processing to digitally calibrate each channel as well as filter and beam form the receive signals. Demonstrating the digital processing required for digital beam forming and digital calibration is instrumental to the viability of the proposed DESDynI instrument. The qFSP development brings this implementation to Technology Readiness Level (TRL) 6. This paper will detail the design and development of the prototype qFSP as well as the preliminary results from hardware tests.

  11. Evaluation of the Effects of Crushed and Expanded Waste Glass Aggregates on the Material Properties of Lightweight Concrete Using Image-Based Approaches.

    PubMed

    Chung, Sang-Yeop; Abd Elrahman, Mohamed; Sikora, Pawel; Rucinska, Teresa; Horszczaruk, Elzbieta; Stephan, Dietmar

    2017-11-25

    Recently, the recycling of waste glass has become a worldwide issue in the reduction of waste and energy consumption. Waste glass can be utilized in construction materials, and understanding its effects on material properties is crucial in developing advanced materials. In this study, recycled crushed and expanded glasses are used as lightweight aggregates for concrete, and their relation to the material characteristics and properties is investigated using several approaches. Lightweight concrete specimens containing only crushed and expanded waste glass as fine aggregates are produced, and their pore and structural characteristics are examined using image-based methods, such as scanning electron microscopy (SEM), X-ray computed tomography (CT), and automated image analysis (RapidAir). The thermal properties of the materials are measured using both Hot Disk and ISOMET devices to enhance measurement accuracy. Mechanical properties are also evaluated, and the correlation between material characteristics and properties is evaluated. As a control group, a concrete specimen with natural fine sand is prepared, and its characteristics are compared with those of the specimens containing crushed and expanded waste glass aggregates. The obtained results support the usability of crushed and expanded waste glass aggregates as alternative lightweight aggregates.

  12. Extended vertical range roughness measurements in non-ideal environments

    NASA Astrophysics Data System (ADS)

    Creath, Katherine

    2011-09-01

    This paper describes recent research into developing an extended range dynamic interferometry technique where the range is extended vertically to enhance surface roughness measurements made in non-ideal environments. Utilizing short pulses from two sources on either side of a frame transfer in a CCD sensor, data can be taken fast enough in noisy shop environments to make measurements in the presence of vibration, and air turbulence. A key application of this technique is monitoring of surface roughness of large optics during the polishing process by making in situ measurements from fine grind through to the final polish. It is anticipated that this monitoring can help speed up what is now a very lengthy process. This same technique is applicable to many other types of measurements including MEMS devices, as it is not affected by dispersion in windows covering devices, and for measuring features on flat panel display glass or semiconductor wafers. This paper describes the technique, and presents results of a variety of sample measurements including: bare glass in various states of polish from fine grind to final polish, scratches and pits in a roughened semiconductor wafer, a DMD MEMS device, and various calibration standards. Performance in terms of repeatabilitity of step heights and roughness for this proof of concept is in the +/-2% range.

  13. Applications of random forest feature selection for fine-scale genetic population assignment.

    PubMed

    Sylvester, Emma V A; Bentzen, Paul; Bradbury, Ian R; Clément, Marie; Pearce, Jon; Horne, John; Beiko, Robert G

    2018-02-01

    Genetic population assignment used to inform wildlife management and conservation efforts requires panels of highly informative genetic markers and sensitive assignment tests. We explored the utility of machine-learning algorithms (random forest, regularized random forest and guided regularized random forest) compared with F ST ranking for selection of single nucleotide polymorphisms (SNP) for fine-scale population assignment. We applied these methods to an unpublished SNP data set for Atlantic salmon ( Salmo salar ) and a published SNP data set for Alaskan Chinook salmon ( Oncorhynchus tshawytscha ). In each species, we identified the minimum panel size required to obtain a self-assignment accuracy of at least 90% using each method to create panels of 50-700 markers Panels of SNPs identified using random forest-based methods performed up to 7.8 and 11.2 percentage points better than F ST -selected panels of similar size for the Atlantic salmon and Chinook salmon data, respectively. Self-assignment accuracy ≥90% was obtained with panels of 670 and 384 SNPs for each data set, respectively, a level of accuracy never reached for these species using F ST -selected panels. Our results demonstrate a role for machine-learning approaches in marker selection across large genomic data sets to improve assignment for management and conservation of exploited populations.

  14. Imaging spectroscopy links aspen genotype with below-ground processes at landscape scales

    PubMed Central

    Madritch, Michael D.; Kingdon, Clayton C.; Singh, Aditya; Mock, Karen E.; Lindroth, Richard L.; Townsend, Philip A.

    2014-01-01

    Fine-scale biodiversity is increasingly recognized as important to ecosystem-level processes. Remote sensing technologies have great potential to estimate both biodiversity and ecosystem function over large spatial scales. Here, we demonstrate the capacity of imaging spectroscopy to discriminate among genotypes of Populus tremuloides (trembling aspen), one of the most genetically diverse and widespread forest species in North America. We combine imaging spectroscopy (AVIRIS) data with genetic, phytochemical, microbial and biogeochemical data to determine how intraspecific plant genetic variation influences below-ground processes at landscape scales. We demonstrate that both canopy chemistry and below-ground processes vary over large spatial scales (continental) according to aspen genotype. Imaging spectrometer data distinguish aspen genotypes through variation in canopy spectral signature. In addition, foliar spectral variation correlates well with variation in canopy chemistry, especially condensed tannins. Variation in aspen canopy chemistry, in turn, is correlated with variation in below-ground processes. Variation in spectra also correlates well with variation in soil traits. These findings indicate that forest tree species can create spatial mosaics of ecosystem functioning across large spatial scales and that these patterns can be quantified via remote sensing techniques. Moreover, they demonstrate the utility of using optical properties as proxies for fine-scale measurements of biodiversity over large spatial scales. PMID:24733949

  15. Implementation of molecular dynamics and its extensions with the coarse-grained UNRES force field on massively parallel systems; towards millisecond-scale simulations of protein structure, dynamics, and thermodynamics

    PubMed Central

    Liwo, Adam; Ołdziej, Stanisław; Czaplewski, Cezary; Kleinerman, Dana S.; Blood, Philip; Scheraga, Harold A.

    2010-01-01

    We report the implementation of our united-residue UNRES force field for simulations of protein structure and dynamics with massively parallel architectures. In addition to coarse-grained parallelism already implemented in our previous work, in which each conformation was treated by a different task, we introduce a fine-grained level in which energy and gradient evaluation are split between several tasks. The Message Passing Interface (MPI) libraries have been utilized to construct the parallel code. The parallel performance of the code has been tested on a professional Beowulf cluster (Xeon Quad Core), a Cray XT3 supercomputer, and two IBM BlueGene/P supercomputers with canonical and replica-exchange molecular dynamics. With IBM BlueGene/P, about 50 % efficiency and 120-fold speed-up of the fine-grained part was achieved for a single trajectory of a 767-residue protein with use of 256 processors/trajectory. Because of averaging over the fast degrees of freedom, UNRES provides an effective 1000-fold speed-up compared to the experimental time scale and, therefore, enables us to effectively carry out millisecond-scale simulations of proteins with 500 and more amino-acid residues in days of wall-clock time. PMID:20305729

  16. Significant Change Spotting for Periodic Human Motion Segmentation of Cleaning Tasks Using Wearable Sensors

    PubMed Central

    Liu, Kai-Chun; Chan, Chia-Tai

    2017-01-01

    The proportion of the aging population is rapidly increasing around the world, which will cause stress on society and healthcare systems. In recent years, advances in technology have created new opportunities for automatic activities of daily living (ADL) monitoring to improve the quality of life and provide adequate medical service for the elderly. Such automatic ADL monitoring requires reliable ADL information on a fine-grained level, especially for the status of interaction between body gestures and the environment in the real-world. In this work, we propose a significant change spotting mechanism for periodic human motion segmentation during cleaning task performance. A novel approach is proposed based on the search for a significant change of gestures, which can manage critical technical issues in activity recognition, such as continuous data segmentation, individual variance, and category ambiguity. Three typical machine learning classification algorithms are utilized for the identification of the significant change candidate, including a Support Vector Machine (SVM), k-Nearest Neighbors (kNN), and Naive Bayesian (NB) algorithm. Overall, the proposed approach achieves 96.41% in the F1-score by using the SVM classifier. The results show that the proposed approach can fulfill the requirement of fine-grained human motion segmentation for automatic ADL monitoring. PMID:28106853

  17. Mapping paddy rice distribution using multi-temporal Landsat imagery in the Sanjiang Plain, northeast China

    PubMed Central

    XIAO, Xiangming; DONG, Jinwei; QIN, Yuanwei; WANG, Zongming

    2016-01-01

    Information of paddy rice distribution is essential for food production and methane emission calculation. Phenology-based algorithms have been utilized in the mapping of paddy rice fields by identifying the unique flooding and seedling transplanting phases using multi-temporal moderate resolution (500 m to 1 km) images. In this study, we developed simple algorithms to identify paddy rice at a fine resolution at the regional scale using multi-temporal Landsat imagery. Sixteen Landsat images from 2010–2012 were used to generate the 30 m paddy rice map in the Sanjiang Plain, northeast China—one of the major paddy rice cultivation regions in China. Three vegetation indices, Normalized Difference Vegetation Index (NDVI), Enhanced Vegetation Index (EVI), and Land Surface Water Index (LSWI), were used to identify rice fields during the flooding/transplanting and ripening phases. The user and producer accuracies of paddy rice on the resultant Landsat-based paddy rice map were 90% and 94%, respectively. The Landsat-based paddy rice map was an improvement over the paddy rice layer on the National Land Cover Dataset, which was generated through visual interpretation and digitalization on the fine-resolution images. The agricultural census data substantially underreported paddy rice area, raising serious concern about its use for studies on food security. PMID:27695637

  18. Microhardness and microstructure evolution of TiB2 reinforced Inconel 625/TiB2 composite produced by selective laser melting

    NASA Astrophysics Data System (ADS)

    Zhang, Baicheng; Bi, Guijun; Nai, Sharon; Sun, Chen-nan; Wei, Jun

    2016-06-01

    In this study, micron-size TiB2 particles were utilized to reinforce Inconel 625 produced by selective laser melting. Exceptional microhardness 600-700 HV0.3 of the composite was obtained. In further investigation, the microstructure and mechanical properties of Inconel 625/TiB2 composite can be significantly influenced by addition of TiB2 particles during SLM. It was found that the long directional columnar grains observed from SLM-processed Inconel 625 were totally changed to fine dendritic matrix due to the addition of TiB2 particles. Moreover, with laser energy density (LED) of 1200 J/m, a Ti, Mo rich interface around TiB2 particles with fine thickness can be observed by FESEM and EDS. The microstructure evolution can be determined by different laser energy density (LED): under 1200 J/m, γ phase in dendrite grains; under 600 J/m, γ phase in combination of dendritic and acicular grains; under 400 J/m, γ phase acicular grains. Under optimized LED 1200 J/m, the dynamic nanohardness (8.62 GPa) and elastic modulus (167 GPa) of SLM-processed Inconel 625/TiB2 composite are higher compared with those of SLM-processed Inconel 625 (3.97 GPa and 135 GPa, respectively).

  19. Experiences in flip chip production of radiation detectors

    NASA Astrophysics Data System (ADS)

    Savolainen-Pulli, Satu; Salonen, Jaakko; Salmi, Jorma; Vähänen, Sami

    2006-09-01

    Modern imaging devices often require heterogeneous integration of different materials and technologies. Because of yield considerations, material availability, and various technological limitations, an extremely fine pitch is necessary to realize high-resolution images. Thus, there is a need for a hybridization technology that is able to join together readout amplifiers and pixel detectors at a very fine pitch. This paper describes radiation detector flip chip production at VTT. Our flip chip technology utilizes 25-μm diameter tin-lead solder bumps at a 50-μm pitch and is based on flux-free bonding. When preprocessed wafers are used, as is the case here, the total yield is defined only partly by the flip chip process. Wafer preprocessing done by a third-party silicon foundry and the flip chip process create different process defects. Wafer-level yield maps (based on probing) provided by the customer are used to select good readout chips for assembly. Wafer probing is often done outside of a real clean room environment, resulting in particle contamination and/or scratches on the wafers. Factors affecting the total yield of flip chip bonded detectors are discussed, and some yield numbers of the process are given. Ways to improve yield are considered, and finally guidelines for process planning and device design with respect to yield optimization are given.

  20. Evaluation of near surface ozone and particulate matter in air ...

    EPA Pesticide Factsheets

    In this study, techniques typically used for future air quality projections are applied to a historical 11-year period to assess the performance of the modeling system when the driving meteorological conditions are obtained using dynamical downscaling of coarse-scale fields without correcting toward higher-resolution observations. The Weather Research and Forecasting model and the Community Multiscale Air Quality model are used to simulate regional climate and air quality over the contiguous United States for 2000–2010. The air quality simulations for that historical period are then compared to observations from four national networks. Comparisons are drawn between defined performance metrics and other published modeling results for predicted ozone, fine particulate matter, and speciated fine particulate matter. The results indicate that the historical air quality simulations driven by dynamically downscaled meteorology are typically within defined modeling performance benchmarks and are consistent with results from other published modeling studies using finer-resolution meteorology. This indicates that the regional climate and air quality modeling framework utilized here does not introduce substantial bias, which provides confidence in the method’s use for future air quality projections. This paper shows that if emissions inputs and coarse-scale meteorological inputs are reasonably accurate, then air quality can be simulated with acceptable accuracy even wi

  1. Vitamin D Requirements for the Future-Lessons Learned and Charting a Path Forward.

    PubMed

    Cashman, Kevin D

    2018-04-25

    Estimates of dietary requirements for vitamin D or Dietary Reference Values (DRV) are crucial from a public health perspective in providing a framework for prevention of vitamin D deficiency and optimizing vitamin D status of individuals. While these important public health policy instruments were developed with the evidence-base and data available at the time, there are some issues that need to be clarified or considered in future iterations of DRV for vitamin D. This is important as it will allow for more fine-tuned and truer estimates of the dietary requirements for vitamin D and thus provide for more population protection. The present review will overview some of the confusion that has arisen in relation to the application and/or interpretation of the definitions of the Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA). It will also highlight some of the clarifications needed and, in particular, how utilization of a new approach in terms of using individual participant-level data (IPD), over and beyond aggregated data, from randomised controlled trials with vitamin D may have a key role in generating these more fine-tuned and truer estimates, which is of importance as we move towards the next iteration of vitamin D DRVs.

  2. Full-potential theoretical investigations of electron inelastic mean free paths and extended x-ray absorption fine structure in molybdenum.

    PubMed

    Chantler, C T; Bourke, J D

    2014-04-09

    X-ray absorption fine structure (XAFS) spectroscopy is one of the most robust, adaptable, and widely used structural analysis tools available for a range of material classes from bulk solids to aqueous solutions and active catalytic structures. Recent developments in XAFS theory have enabled high-accuracy calculations of spectra over an extended energy range using full-potential cluster modelling, and have demonstrated particular sensitivity in XAFS to a fundamental electron transport property-the electron inelastic mean free path (IMFP). We develop electron IMFP theory using a unique hybrid model that simultaneously incorporates second-order excitation losses, while precisely accounting for optical transitions dictated by the complex band structure of the solid. These advances are coupled with improved XAFS modelling to determine wide energy-range absorption spectra for molybdenum. This represents a critical test case of the theory, as measurements of molybdenum K-edge XAFS represent the most accurate determinations of XAFS spectra for any material. We find that we are able to reproduce an extended range of oscillatory structure in the absorption spectrum, and demonstrate a first-time theoretical determination of the absorption coefficient of molybdenum over the entire extended XAFS range utilizing a full-potential cluster model.

  3. Effects of Fineness Ratio and Reynolds Number on the Low-Speed Crosswind Drag Characteristics of Circular and Modified-Square Cylinders

    NASA Technical Reports Server (NTRS)

    McKinney, Linwood W.

    1960-01-01

    A wind-tunnel investigation has been made on modified-square and circular cylinders to determine the effects of fineness ratio and Reynolds numbers on the crosswind drag characteristics. Fineness ratios from 2 to 14 were investigated over a Reynolds number range from approximately 300,000 to 1,650,000 which corresponded to Mach numbers from 0.057 to 0.377.The result of the investigation show that at supercraft Reynolds numbers the drag coefficient of the circular cylinder increases with increasing Reynolds number for all fineness ratios but at low fineness ratios this effect is considerably less than at higher fineness ratios. For circular cylinders in the high fineness-ratio range there is a reduction in drag as the fineness ratio is decreased except for Reynolds numbers of 900,000 and 1,000,000, whereas at low fineness ratios the opposite trend generally occurs. The addition of hemispherical ends to the circular cylinder gave a substantial decrease in drag at a fineness ratio of 3.27 but the effect was negligible at fineness ratios of 5.27 and 10. The finite-length modified-square cylinder gave the reduction in drag over the two-dimensional modified-square cylinder for the complete range of test Reynolds numbers with the lowest fineness ratio giving the lowest drag at Reynolds numbers above 3O0,OOO.

  4. 8 CFR 1280.5 - Mitigation or remission of fines.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Mitigation or remission of fines. 1280.5... IMMIGRATION REGULATIONS IMPOSITION AND COLLECTION OF FINES § 1280.5 Mitigation or remission of fines. In any case in which mitigation or remission of a fine is authorized by the Immigration and Nationality Act...

  5. 8 CFR 1280.5 - Mitigation or remission of fines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Mitigation or remission of fines. 1280.5... IMMIGRATION REGULATIONS IMPOSITION AND COLLECTION OF FINES § 1280.5 Mitigation or remission of fines. In any case in which mitigation or remission of a fine is authorized by the Immigration and Nationality Act...

  6. Fine Root Productivity and Dynamics on a Forested Floodplain in South Carolina

    Treesearch

    Terrell T. Baker; William Conner; H. B. Graeme Lockaby; John A. Stanturf

    2001-01-01

    The highly dynamic, fine root component of forested wetland ecosystems fine root dynamics is a challenging endeavor in any system, but the difficulties are particularly evident in forested floodplains where frequent hydrologic fluctuations directly influence fine root dynamics. Fine root (53 mm) biomass, production, and turnover were estimated for three soils...

  7. [Fine root dynamics and its relationship with soil fertility in tropical rainforests of Chocó].

    PubMed

    Quinto, Harley; Caicedo, Haylin; Thelis Perez, May; Moreno, Flavio

    2016-12-01

    The fine roots play an important role in the acquisition of water and minerals from the soil, the global carbon balance and mitigation of climate change. The dynamics (productivity and turnover) of fine roots is essential for nutrient cycling and carbon balance of forest ecosystems. The availability of soil water and nutrients has significantly determined the productivity and turnover of fine roots. It has been hypothesized that fine roots dynamics increases with the availability of soil resources in tropical forest ecosystems. To test this hypothesis in tropical rainforests of Chocó (ecosystems with the highest rainfall in the world), five one-ha permanent plots were established in the localities of Opogodó and Pacurita, where the productivity and turnover of fine roots were measured at 0-10 cm and 10-20 cm depth. The measurement of the fine root production was realized by the Ingrowth core method. The fine root turnover was measured like fine roots production divided mean annual biomass. In addition, soil fertility parameters (pH, nutrients, and texture) were measured and their association with productivity and turnover of fine roots was evaluated. It was found that the sites had nutrient-poor soils. The localities also differ in soil; Opogodó has sandy soils and flat topography, and Pacurita has clay soils, rich in aluminum and mountainous topography. In Opogodó fine root production was 6.50 ± 2.62 t/ha.yr (mean ± SD). In Pacurita, fine root production was 3.61 ± 0.88 t/ha.yr. Also in Opogodó, the fine root turnover was higher than in Pacurita (1.17 /y and 0.62 /y, respectively). Fine root turnover and production in the upper soil layers (10 cm upper soil) was considerably higher. Productivity and turnover of fine roots showed positive correlation with pH and contents of organic matter, total N, K, Mg, and sand; whereas correlations were negative with ECEC and contents of Al, silt, and clay. The percentage of sand was the parameter that best explained the variations of fine root production. The fine root turnover was negatively explained by soil Al availability. Results suggested the increase of fine root dynamics with soil fertility at a local scale, which also indicates that under the oligotrophic conditions of soils in tropical rainforests, fine roots tend to proliferate rapidly in small patches of soil rich in sand and nutrients.

  8. Interactions Between Pinus taeda (loblolly) Fine Roots and Soil Fungi: Impacts of Elevated CO2, N Availability, and Spatial Distribution of Fungi on Fine Root Persistence and Turnover

    NASA Astrophysics Data System (ADS)

    Strand, A.; Beidler, K.; McGlinn, D.; Pritchard, S. G.

    2016-12-01

    Fine root turnover represents the most significant mode of flux from plants into soil C pools. Unfortunately fine root senescence and decomposition, processes critical in turnover, are particularly understudied. For example, little is known about either the factors that influence fine-root decomposition or the fate of compounds they contain during root death. Better understanding fine root senescence and decomposition should reduce uncertainty associated with global climate models; including re-uptake of materials in dying leaves into these models has already been shown to increase their accuracy. Over 4400 individual fine-roots and 4734 rhizomorphs were tracked from initiation until disintegration over 12 years using minirhizotrons at the Duke FACE site. Image-based approaches such as minirhizotrons cannot directly assess fine-root physiological status. To assess fine-root function directly, we are now conducting manipulative experiments in P. taeda in which fine-root senescence is induced through two treatments, steam- and direct hand-girdling. Physiological status is then assessed by examining gene-expression, root anatomy and chemical composition of manipulated roots. Changing [CO2] did not change persistence times for roots, but did impact rhizomorph persistence. Both roots and rhizomorphs showed interactions between effects of N and CO2 on persistence. Most interesting is the interaction between fine-roots and rhizomorphs: fine root persistence times are reduced in the presence of rhizomorphs, but this effect depends on the amount of N available. Finally, we found experimentally inducing senescence via steam girdling to be very effective relative to hand-girdling. These results provide evidence of the importance of priming on function of soil fungi and the role of N availability on fine-root turnover. The ability to stimulate fine-root senescence provides a powerful experimental tool to examine the fates of resources contained in fine-root pools as these roots turn over.

  9. Redefining fine roots improves understanding of belowground contributions to terrestrial biosphere processes

    DOE PAGES

    McCormack, M. Luke; Dickie, Ian A.; Eissenstat, David M.; ...

    2015-03-10

    Fine roots acquire essential soil resources and mediate biogeochemical cycling in terrestrial ecosystems. Estimates of carbon and nutrient allocation to build and maintain these structures remain uncertain due to challenges in consistent measurement and interpretation of fine-root systems. We define fine roots as all roots less than or equal to 2 mm in diameter, yet it is now recognized that this approach fails to capture the diversity of form and function observed among fine-root orders. We demonstrate how order-based and functional classification frameworks improve our understanding of dynamic root processes in ecosystems dominated by perennial plants. In these frameworks, finemore » roots are separated into either individual root orders or functionally defined into a shorter-lived absorptive pool and a longer-lived transport fine root pool. Furthermore, using these frameworks, we estimate that fine-root production and turnover represent 22% of terrestrial net primary production globally a ca. 30% reduction from previous estimates assuming a single fine-root pool. In the future we hope to develop tools to rapidly differentiate functional fine-root classes, explicit incorporation of mycorrhizal fungi in fine-root studies, and wider adoption of a two-pool approach to model fine roots provide opportunities to better understand belowground processes in the terrestrial biosphere.« less

  10. [Coal fineness effect on primary particulate matter features during pulverized coal combustion].

    PubMed

    Lü, Jian-yi; Li, Ding-kai

    2007-09-01

    Three kinds of coal differed from fineness were burned in a laboratory-scale drop tube furnace for combustion test, and an 8-stage Andersen particle impactor was employed for sampling the primary particulate matter (PM), in order to study coal fineness effect on primary PM features during pulverized coal combustion. It has been shown that the finer the coal was, the finer the PM produced. PM, emission amount augmented with coal fineness decreased, and the amount of PM10 increased from 13 mg/g to 21 mg/g respectively generated by coarse coal and fine coal. The amount of PM2.5 increased from 2 mg/g to 8 mg/g at the same condition. Constituents and content in bulk ash varied little after three different fineness coal combustion, while the appearance of grading PM differed visibly. The value of R(EE) increased while the coal fineness deceased. The volatility of trace elements which were investigated was Pb > Cr > Zn > Cu > Ni in turn. The concentration of poisonous trace elements was higher which generated from fine coal combustion. The volatilization capacity was influenced little by coal fineness, but the volatilization extent was influenced differently by coal fineness. Fine coal combustion affects worse environment than coarse coal does.

  11. Effectiveness and cost-effectiveness of fining non-attendance at public hospitals: a randomised controlled trial from Danish outpatient clinics.

    PubMed

    Blæhr, Emely Ek; Væggemose, Ulla; Søgaard, Rikke

    2018-04-13

    Fines have been proposed as means for reducing non-attendance in healthcare. The empirical evidence of the effect of fines is however limited. The objective of this study is to investigate the effectiveness and cost-effectiveness of fining non-attendance at outpatient clinics. 1:1 randomised controlled trial of appointments for an outpatient clinic, posted to Danish addresses, between 1 May 2015 and 30 November 2015. Only first appointment for users was included. Healthcare professionals and investigators were masked. A fine of DKK250 (€34) was issued for non-attendance. Users were informed about the fine in case of non-attendance by the appointment letter, and were able to reschedule or cancel until the appointment. A central administration office administered the fine system. The main outcome measures were non-attendance of non-cancelled appointments, fine policy administration costs, net of productivity consequences and probability of fining non-attendance being cost-effective over no fining for a range of hypothetical values of reduced non-attendance. All of the 6746 appointments included were analysed. Of the 3333 appointments randomised to the fine policy, 130 (5%) of non-cancelled appointments were unattended, and of the 3413 appointments randomised to no-fine policy, 131 (5%) were unattended. The cost per appointment of non-attendance was estimated at DKK 56 (SE 5) in the fine group and DKK47 (SE 4) in the no-fine group, leading to a non-statistically significant difference of DKK10 (95% CI -9 to 22) per appointment attributable to the fine policy. The probability of cost-effectiveness remained around 50%, irrespective of increased values of reduced non-attendance or various alternative assumptions used for sensitivity analyses. At a baseline level of around 5%, fining non-attendance does not seem to further reduce non-attendance. Future studies should focus on other means for reduction of non-attendance such as nudging or negative reinforcement. ISRCTN61925912. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  12. Effectiveness and cost-effectiveness of fining non-attendance at public hospitals: a randomised controlled trial from Danish outpatient clinics

    PubMed Central

    Væggemose, Ulla; Søgaard, Rikke

    2018-01-01

    Objectives Fines have been proposed as means for reducing non-attendance in healthcare. The empirical evidence of the effect of fines is however limited. The objective of this study is to investigate the effectiveness and cost-effectiveness of fining non-attendance at outpatient clinics. Design, participants and setting 1:1 randomised controlled trial of appointments for an outpatient clinic, posted to Danish addresses, between 1 May 2015 and 30 November 2015. Only first appointment for users was included. Healthcare professionals and investigators were masked. Intervention A fine of DKK250 (€34) was issued for non-attendance. Users were informed about the fine in case of non-attendance by the appointment letter, and were able to reschedule or cancel until the appointment. A central administration office administered the fine system. Main outcome measures The main outcome measures were non-attendance of non-cancelled appointments, fine policy administration costs, net of productivity consequences and probability of fining non-attendance being cost-effective over no fining for a range of hypothetical values of reduced non-attendance. Results All of the 6746 appointments included were analysed. Of the 3333 appointments randomised to the fine policy, 130 (5%) of non-cancelled appointments were unattended, and of the 3413 appointments randomised to no-fine policy, 131 (5%) were unattended. The cost per appointment of non-attendance was estimated at DKK 56 (SE 5) in the fine group and DKK47 (SE 4) in the no-fine group, leading to a non-statistically significant difference of DKK10 (95% CI –9 to 22) per appointment attributable to the fine policy. The probability of cost-effectiveness remained around 50%, irrespective of increased values of reduced non-attendance or various alternative assumptions used for sensitivity analyses. Conclusions At a baseline level of around 5%, fining non-attendance does not seem to further reduce non-attendance. Future studies should focus on other means for reduction of non-attendance such as nudging or negative reinforcement. Trial registration number ISRCTN61925912. PMID:29654019

  13. The Role of Authigenic (pigment) Hematite in Controlling the Remanence, Rock Magnetic, and Magnetic Fabric Properties of Red Beds--If You Have Seen One Red Bed, You Certainly Have Not Seen Them All!

    NASA Astrophysics Data System (ADS)

    Geissman, J. W.

    2014-12-01

    Discussion continues on the relative role of authigenic (pigment) fine-grained hematite, relative to detrital, considerably coarser specular hematite (specularite) as a carrier of geologically meaningful remanence, as a determinant of rock magnetic properties, and as a contributor to magnetic fabrics in red beds. For one, many workers commonly assume that the laboratory unblocking temperature spectra (Tlub) of a red bed dominated by authigenic pigment does not reach the maximum Tlub as approximated by the Neel temperature (~948 K) because of the ultra fine grain size of the pigment. This issue was discussed as recently as the IRM Santa Fe meeting in late June, 2014. Many laboratories routinely utilize chemical demagnetization in concert with progressive thermal demagnetization to attempt to assess the relative role of pigment vs. detrital hematite. However, the utility of chemical demagnetization has been long challenged. In studying the anisotropy of magnetic susceptibility and remanence in red beds, recent work has considered separating the contributions of both types of hematite to the fabric signal. Three different red bed "types" (siltstones of the Triassic Chugwater Group, Gros Ventre Range, Wyoming; mudrocks of lowermost Triassic Quartermaster Formation, west Texas; and siltstones to medium sandstones of Upper Cretaceous age, northwest Vietnam) are used to evaluate the effects of varying contributions by pigment hematite to remanence, rock magnetic, and magnetic fabric properties. All rocks are well-characterized petrographically, so that the modal abundance of detrital oxides is known. The Chugwater siltstones are notable because of a relatively low Tlub spectra (below about 620o C), with no evidence of a low coercivity cubic phase. Rock magnetic and magnetic fabric properties are monitored as a function of progressive chemical demagnetization to further elucidate the role of hematite pigment in rocks that have contributed much to the paleomagnetic record of Earth.

  14. Compositional Analysis of Fine Particulate Matter in Fairbanks, Alaska

    NASA Astrophysics Data System (ADS)

    Nattinger, K.; Simpson, W. R.; Huff, D.

    2015-12-01

    Fairbanks, AK experiences extreme pollution episodes that result in winter violations of the fine particulate matter (PM2.5) National Ambient Air Quality Standards. This poses a significant health risk for the inhabitants of the area. These high levels result from trapping of pollution in a very shallow boundary layer due to local meteorology, but the role of primary (direct emission) of particulate matter versus secondary production (in the atmosphere) of particulate matter is not understood. Analysis of the PM2.5 composition is being conducted to provide insight into sources, trends, and chemistry. Methods are developed to convert carbon data from IMPROVE (post-2009 analysis method) to NIOSH (pre-2009 method) utilizing blank subtraction, sampler bias adjustment, and inter-method correlations from co-located samples. By converting all carbon measurements to a consistent basis, long-term trends can be analyzed. The approach shows excellent mass closure between PM2.5 mass reconstructed from constituents and gravimetric-analyzed mass. This approach could be utilized in other US locations where the carbon analysis methods also changed. Results include organic and inorganic fractional mass percentages, analyzed over an eight-year period for two testing sites in Fairbanks and two in the nearby city of North Pole. We focus on the wintertime (Nov—Feb) period when most air quality violations occur and find that the particles consist primarily of organic carbon, with smaller percentages of sulfate, elemental carbon, ammonium, and nitrate. The Fairbanks area PM2.5 organic carbon / elemental carbon partitioning matches the source profile of wood smoke. North Pole and Fairbanks PM2.5 have significant compositional differences, with North Pole having a larger percentage of organic matter. Mass loadings in SO42-, NO3-, and total PM2.5 mass correlate with temperature. Multi-year temporal trends show little if any change with a strong effect from temperature. Insights from this study regarding primary versus possible secondary PM2.5 production processes can help in identifying effective PM2.5 control strategies.

  15. Estimating movement and survival rates of a small saltwater fish using autonomous antenna receiver arrays and passive integrated transponder tags

    USGS Publications Warehouse

    Rudershausen, Paul J.; Buckel, Jeffery A.; Dubreuil, Todd; O'Donnell, Matthew J.; Hightower, Joseph E.; Poland, Steven J.; Letcher, Benjamin H.

    2014-01-01

    We evaluated the performance of small (12.5 mm long) passive integrated transponder (PIT) tags and custom detection antennas for obtaining fine-scale movement and demographic data of mummichog Fundulus heteroclitus in a salt marsh creek. Apparent survival and detection probability were estimated using a Cormack Jolly Seber (CJS) model fitted to detection data collected by an array of 3 vertical antennas from November 2010 to March 2011 and by a single horizontal antenna from April to August 2011. Movement of mummichogs was monitored during the period when the array of vertical antennas was used. Antenna performance was examined in situ using tags placed in wooden dowels (drones) and in live mummichogs. Of the 44 tagged fish, 42 were resighted over the 9 mo monitoring period. The in situ detection probabilities of the drone and live mummichogs were high (~80-100%) when the ambient water depth was less than ~0.8 m. Upstream and downstream movement of mummichogs was related to hourly water depth and direction of tidal current in a way that maximized time periods over which mummichogs utilized the intertidal vegetated marsh. Apparent survival was lower during periods of colder water temperatures in December 2010 and early January 2011 (median estimate of daily apparent survival = 0.979) than during other periods of the study (median estimate of daily apparent survival = 0.992). During late fall and winter, temperature had a positive effect on the CJS detection probability of a tagged mummichog, likely due to greater fish activity over warmer periods. During the spring and summer, this pattern reversed possibly due to mummichogs having reduced activity during the hottest periods. This study demonstrates the utility of PIT tags and continuously operating autonomous detection systems for tracking fish at fine temporal scales, and improving estimates of demographic parameters in salt marsh creeks that are difficult or impractical to sample with active fishing gear.

  16. Predicting residential indoor concentrations of nitrogen dioxide, fine particulate matter, and elemental carbon using questionnaire and geographic information system based data

    NASA Astrophysics Data System (ADS)

    Baxter, Lisa K.; Clougherty, Jane E.; Paciorek, Christopher J.; Wright, Rosalind J.; Levy, Jonathan I.

    Previous studies have identified associations between traffic-related air pollution and adverse health effects. Most have used measurements from a few central ambient monitors and/or some measure of traffic as indicators of exposure, disregarding spatial variability and factors influencing personal exposure-ambient concentration relationships. This study seeks to utilize publicly available data (i.e., central site monitors, geographic information system, and property assessment data) and questionnaire responses to predict residential indoor concentrations of traffic-related air pollutants for lower socioeconomic status (SES) urban households. As part of a prospective birth cohort study in urban Boston, we collected indoor and outdoor 3-4 day samples of nitrogen dioxide (NO 2) and fine particulate matter (PM 2.5) in 43 low SES residences across multiple seasons from 2003 to 2005. Elemental carbon (EC) concentrations were determined via reflectance analysis. Multiple traffic indicators were derived using Massachusetts Highway Department data and traffic counts collected outside sampling homes. Home characteristics and occupant behaviors were collected via a standardized questionnaire. Additional housing information was collected through property tax records, and ambient concentrations were collected from a centrally located ambient monitor. The contributions of ambient concentrations, local traffic and indoor sources to indoor concentrations were quantified with regression analyses. PM 2.5 was influenced less by local traffic but had significant indoor sources, while EC was associated with traffic and NO 2 with both traffic and indoor sources. Comparing models based on covariate selection using p-values or a Bayesian approach yielded similar results, with traffic density within a 50 m buffer of a home and distance from a truck route as important contributors to indoor levels of NO 2 and EC, respectively. The Bayesian approach also highlighted the uncertanity in the models. We conclude that by utilizing public databases and focused questionnaire data we can identify important predictors of indoor concentrations for multiple air pollutants in a high-risk population.

  17. Modeling Co-Extruded Cathodes for High Energy Lithium-Ion Batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cobb, Corie Lynn

    2016-06-01

    Utilizing an existing macro-homogeneous porous electrode model developed by John Newman, this talk presents the potential energy density gains that can be realized in lithium-ion battery electrodes fabricated with co-extrusion (CoEx) technology. CoEx uses carefully engineered fluidic channels to cause multiple streams of dissimilar fluids to impart shape to one another. The result is a high-speed, continuous deposition process that can create fine linear structures much smaller than the smallest physical feature within the printhead. By eliminating the small channels necessary for conventional extrusion and injection processes, CoEx is able to deposit highly loaded and viscous pastes at high linemore » speeds under reasonable operating pressures. The CoEx process is capable of direct deposition of features as small as 10 μm with aspect ratios of 5 or greater, and print speeds > 80 ft/min. We conduct an analysis on two-dimensional cathode cross-sections in COMSOL and present the electrochemical performance results, including calculated volumetric energy capacity for Lithium Nickel Manganese Cobalt Oxide (NMC) co-extruded cathodes, in the presence of a lithium metal anode, polymer separator and ethylene carbonate–diethyl carbonate (EC:DEC) liquid electrolyte. The impact of structured electrodes on cell performance is investigated by varying the physical distribution of a fixed amount of cathode mass over a space of dimensions which can be fabricated by CoEx. By systematically varying the thickness and aspect ratio of the electrode structures, we present an optimal subset of geometries and design rules for co-extruded geometries. Modeling results demonstrate that NMC CoEx cathodes, on the order of 125-200 µm thick, can garner an improvement in material utilization and in turn capacity through the addition of fine width electrolyte channels or highly conductive electrode regions. We also present initial experimental results on CoEx NMC cathode structures.« less

  18. Utilizing borehole electrical images to interpret lithofacies of fan-delta: A case study of Lower Triassic Baikouquan Formation in Mahu Depression, Junggar Basin, China

    NASA Astrophysics Data System (ADS)

    Yuan, Rui; Zhang, Changmin; Tang, Yong; Qu, Jianhua; Guo, Xudong; Sun, Yuqiu; Zhu, Rui; Zhou, Yuanquan (Nancy)

    2017-11-01

    Large-scale conglomerate fan-delta aprons were typical deposits on the slope of Mahu Depression during the Early Triassic. Without outcrops, it is difficult to study the lithofacies only by examining the limited cores from the main oil-bearing interval of the Baikouquan Formation. Borehole electrical imaging log provides abundant high-resolution geologic information that is obtainable only from real rocks previously. Referring to the lithology and sedimentary structure of cores, a case study of fan-deltas in the Lower Triassic Baikouquan Formation of the Mahu Depression presents a methodology for interpreting the complicated lithofacies utilizing borehole electrical images. Eleven types of lithologies and five types of sedimentary structures are summarized in borehole electrical images. The sediments are fining upward from gravel to silt and clay in the Baikouquan Formation. Fine-pebbles and granules are the main deposits in T1b1 and T1b2, but sandstones, siltstones and mudstones are more developed in T1b3. The main sedimentary textures are massive beddings, cross beddings and scour-and-fill structures. Parallel and horizontal beddings are more developed in T1b3 relatively. On integrated analysis of the lithology and sedimentary structure, eight lithofacies from electrical images, referred to as image lithofacies, is established for the fan-deltas. Granules to coarse-pebbles within massive beddings, granules to coarse-pebbles within cross and parallel beddings, siltstones within horizontal and massive beddings are the most developed lithofacies respectively in T1b1, T1b2 and T1b3. It indicates a gradual rise of the lake level of Mahu depression during the Early Triassic, with the fan-delta aprons retrograding towards to the margin of the basin. Therefore, the borehole electrical imaging log compensate for the limitation of cores of the Baikouquan Formation, providing an effective new approach to interpret the lithofacies of fan-delta.

  19. Get out of Fines Free: Recruiting Student Usability Testers via Fine Waivers

    ERIC Educational Resources Information Center

    Hockenberry, Benjamin; Blackburn, Kourtney

    2016-01-01

    St. John Fisher College's Lavery Library's Access Services and Systems departments began a pilot project in which students with overdue fines tested usability of library Web sites in exchange for fine waivers. Circulation staff promoted the program and redeemed fine waiver vouchers at the Checkout Desk, while Systems staff administered testing and…

  20. 8 CFR 280.5 - Mitigation or remission of fines.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Mitigation or remission of fines. 280.5... AND COLLECTION OF FINES § 280.5 Mitigation or remission of fines. In any case in which mitigation or... Examinations, or the Director for the National Fines Office for such mitigation or remission. [22 FR 9807, Dec...

  1. 8 CFR 280.5 - Mitigation or remission of fines.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Mitigation or remission of fines. 280.5... AND COLLECTION OF FINES § 280.5 Mitigation or remission of fines. In any case in which mitigation or... Examinations, or the Director for the National Fines Office for such mitigation or remission. [22 FR 9807, Dec...

  2. 8 CFR 280.5 - Mitigation or remission of fines.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Mitigation or remission of fines. 280.5... AND COLLECTION OF FINES § 280.5 Mitigation or remission of fines. In any case in which mitigation or... Examinations, or the Director for the National Fines Office for such mitigation or remission. [22 FR 9807, Dec...

  3. 8 CFR 280.5 - Mitigation or remission of fines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Mitigation or remission of fines. 280.5... AND COLLECTION OF FINES § 280.5 Mitigation or remission of fines. In any case in which mitigation or... Examinations, or the Director for the National Fines Office for such mitigation or remission. [22 FR 9807, Dec...

  4. 8 CFR 280.5 - Mitigation or remission of fines.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Mitigation or remission of fines. 280.5... AND COLLECTION OF FINES § 280.5 Mitigation or remission of fines. In any case in which mitigation or... Examinations, or the Director for the National Fines Office for such mitigation or remission. [22 FR 9807, Dec...

  5. 76 FR 31307 - Commission of Fine Arts; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... COMMISSION OF FINE ARTS Commission of Fine Arts; Notice of Meeting The next meeting of the U.S. Commission of Fine Arts is scheduled for June 16, 2011, at 10 a.m. in the Commission offices at the National... Fine Arts, at the above address; by emailing [email protected] ; or by calling 202-504-2200. Individuals...

  6. Surgical implications of B-RafV600E mutation in fine-needle aspiration of thyroid nodules

    PubMed Central

    Mekel, Michal; Nucera, Carmelo; Hodin, Richard A.; Parangi, Sareh

    2013-01-01

    BACKGROUND Management of patients with thyroid nodules is based on establishing an accurate diagnosis; however, differentiating benign from malignant lesions preoperatively is not always possible using current cytological techniques. Novel molecular testing on cytological material could lead to clearer treatment algorithms. B-RafV600E mutation is the most common genetic alteration in thyroid cancer, specifically found in papillary thyroid cancer (PTC), and usually reported to be associated with aggressive disease. DATA SOURCE A literature search using PubMed identified all the pertinent literature on the identification and utilization of the B-RafV600E mutation in thyroid cancer. CONCLUSIONS The utility of using B-Raf mutation testing for nodules with indeterminate cytology is limited since many of those nodules (benign and malignant) do not harbor B-Raf mutations. However, when the pathologist sees cytological features suspicious for PTC, B-RafV600E mutation analysis may enhance the assessment of preoperative risks for PTC, directing a more aggressive initial surgical management when appropriate. PMID:20637346

  7. Parallel Monte Carlo transport modeling in the context of a time-dependent, three-dimensional multi-physics code

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Procassini, R.J.

    1997-12-31

    The fine-scale, multi-space resolution that is envisioned for accurate simulations of complex weapons systems in three spatial dimensions implies flop-rate and memory-storage requirements that will only be obtained in the near future through the use of parallel computational techniques. Since the Monte Carlo transport models in these simulations usually stress both of these computational resources, they are prime candidates for parallelization. The MONACO Monte Carlo transport package, which is currently under development at LLNL, will utilize two types of parallelism within the context of a multi-physics design code: decomposition of the spatial domain across processors (spatial parallelism) and distribution ofmore » particles in a given spatial subdomain across additional processors (particle parallelism). This implementation of the package will utilize explicit data communication between domains (message passing). Such a parallel implementation of a Monte Carlo transport model will result in non-deterministic communication patterns. The communication of particles between subdomains during a Monte Carlo time step may require a significant level of effort to achieve a high parallel efficiency.« less

  8. Stem Cell Metabolism in Cancer and Healthy Tissues: Pyruvate in the Limelight

    PubMed Central

    Corbet, Cyril

    2018-01-01

    Normal and cancer stem cells (CSCs) share the remarkable potential to self-renew and differentiate into many distinct cell types. Although most of the stem cells remain under quiescence to maintain their undifferentiated state, they can also undergo cell divisions as required to regulate tissue homeostasis. There is now a growing evidence that cell fate determination from stem cells implies a fine-tuned regulation of their energy balance and metabolic status. Stem cells can shift their metabolic substrate utilization, between glycolysis and mitochondrial oxidative metabolism, during specification and/or differentiation, as well as in order to adapt their microenvironmental niche. Pyruvate appears as a key metabolite since it is at the crossroads of cytoplasmic glycolysis and mitochondrial oxidative phosphorylation. This Review describes how metabolic reprogramming, focusing on pyruvate utilization, drives the fate of normal and CSCs by modulating their capacity for self-renewal, clonal expansion/differentiation, as well as metastatic potential and treatment resistance in cancer. This Review also explores potential therapeutic strategies to restore or manipulate stem cell function through the use of small molecules targeting the pyruvate metabolism. PMID:29403375

  9. Surface Texture-Induced Enhancement of Optical and Photoelectrochemical Activity of Cu2ZnSnS4 Photocathodes

    NASA Astrophysics Data System (ADS)

    Sarswat, Prashant K.; Deka, Nipon; Jagan Mohan Rao, S.; Free, Michael L.; Kumar, Gagan

    2017-08-01

    The objective of this work is to understand and improve the photocatalytic activity of Cu2ZnSnS4 (CZTS) through postgrowth modification techniques to create surface textures. This objective can be achieved using a combination of solvents, etching agents, and anodization techniques. One of the most effective surface treatments for enhancing the surface properties of photovoltaic materials is formation of nanoscale flakes, although other surface modifications were also evaluated. The superior performance of textured films can be attributed to enhanced surface area of absorber material exposed to electrolyte, ZnS deficiency, and high catalytic activity due to reduced charge-transfer resistance. Fine-tuning of ion flux and electrolyte stoichiometry can be used to create a controlled growth algorithm for CZTS thin films. The resulting information can be utilized to optimize film properties. The utility of nanostructured or engineered surfaces was evaluated using photoelectrochemical measurements. Finite-difference time-domain (FDTD)-assisted simulations were conducted for selected texturing, revealing enhanced surface area of absorbing medium that ultimately resulted in greater power loss of light in the medium.

  10. NASA Products to Enhance Energy Utility Load Forecasting

    NASA Technical Reports Server (NTRS)

    Lough, G.; Zell, E.; Engel-Cox, J.; Fungard, Y.; Jedlovec, G.; Stackhouse, P.; Homer, R.; Biley, S.

    2012-01-01

    Existing energy load forecasting tools rely upon historical load and forecasted weather to predict load within energy company service areas. The shortcomings of load forecasts are often the result of weather forecasts that are not at a fine enough spatial or temporal resolution to capture local-scale weather events. This project aims to improve the performance of load forecasting tools through the integration of high-resolution, weather-related NASA Earth Science Data, such as temperature, relative humidity, and wind speed. Three companies are participating in operational testing one natural gas company, and two electric providers. Operational results comparing load forecasts with and without NASA weather forecasts have been generated since March 2010. We have worked with end users at the three companies to refine selection of weather forecast information and optimize load forecast model performance. The project will conclude in 2012 with transitioning documented improvements from the inclusion of NASA forecasts for sustained use by energy utilities nationwide in a variety of load forecasting tools. In addition, Battelle has consulted with energy companies nationwide to document their information needs for long-term planning, in light of climate change and regulatory impacts.

  11. Development of new SNP derived cleaved amplified polymorphic sequence marker set and its successful utilization in the genetic analysis of seed color variation in barley.

    PubMed

    Bungartz, Annemarie; Klaus, Marius; Mathew, Boby; Léon, Jens; Naz, Ali Ahmad

    2016-03-01

    The aim of the present study was to develop a new cost effective PCR based CAPS marker set using advantages of high-throughput SNP genotyping. Initially, SNP survey was made using 20 diverse barley genotypes via 9k iSelect array genotyping that resulted in 6334 polymorphic SNP markers. Principle component analysis using this marker data showed fine differentiation of barley diverse gene pool. Till this end, we developed 200 SNP derived CAPS markers distributed across the genome covering around 991cM with an average marker density of 5.09cM. Further, we genotyped 68 CAPS markers in an F2 population (Cheri×ICB181160) segregating for seed color variation in barley. Genetic mapping of seed color revealed putative linkage of single nuclear gene on chromosome 1H. These findings showed the proof of concept for the development and utility of a newer cost effective genomic tool kit to analyze broader genetic resources of barley worldwide. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Commercial-scale demonstration of the Liquid Phase Methanol (LPMEOH{trademark}) process. Technical progress report number 9, July 1--September 30, 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The Liquid Phase Methanol (LPMEOH{trademark}) Demonstration Project at Kingsport, Tennessee, is a $213.7 million cooperative agreement between the US Department of Energy (DOE) and Air Products Liquid Phase Conversion Company, L.P. (the Partnership). The LPMEOH{trademark} Process Demonstration Unit is being built at a site located at the Eastman Chemical Company (Eastman) complex in Kingsport. The project involves the construction of an 80,000 gallons per day (260 tons per day (TPD)) methanol unit utilizing coal-derived synthesis gas from Eastman`s integrated coal gasification facility. The new equipment consists of synthesis gas feed preparation and compression facilities, the liquid phase reactor and auxiliaries,more » product distillation facilities, and utilities. This liquid phase process suspends fine catalyst particles in an inert liquid, forming a slurry. The slurry dissipates the heat of the chemical reaction away from the catalyst surface, protecting the catalyst and allowing the methanol synthesis reaction to proceed at higher rates. At the Eastman complex, the technology is being integrated with existing coal-gasifiers.« less

  13. A statistical approach to optimizing concrete mixture design.

    PubMed

    Ahmad, Shamsad; Alghamdi, Saeid A

    2014-01-01

    A step-by-step statistical approach is proposed to obtain optimum proportioning of concrete mixtures using the data obtained through a statistically planned experimental program. The utility of the proposed approach for optimizing the design of concrete mixture is illustrated considering a typical case in which trial mixtures were considered according to a full factorial experiment design involving three factors and their three levels (3(3)). A total of 27 concrete mixtures with three replicates (81 specimens) were considered by varying the levels of key factors affecting compressive strength of concrete, namely, water/cementitious materials ratio (0.38, 0.43, and 0.48), cementitious materials content (350, 375, and 400 kg/m(3)), and fine/total aggregate ratio (0.35, 0.40, and 0.45). The experimental data were utilized to carry out analysis of variance (ANOVA) and to develop a polynomial regression model for compressive strength in terms of the three design factors considered in this study. The developed statistical model was used to show how optimization of concrete mixtures can be carried out with different possible options.

  14. A Statistical Approach to Optimizing Concrete Mixture Design

    PubMed Central

    Alghamdi, Saeid A.

    2014-01-01

    A step-by-step statistical approach is proposed to obtain optimum proportioning of concrete mixtures using the data obtained through a statistically planned experimental program. The utility of the proposed approach for optimizing the design of concrete mixture is illustrated considering a typical case in which trial mixtures were considered according to a full factorial experiment design involving three factors and their three levels (33). A total of 27 concrete mixtures with three replicates (81 specimens) were considered by varying the levels of key factors affecting compressive strength of concrete, namely, water/cementitious materials ratio (0.38, 0.43, and 0.48), cementitious materials content (350, 375, and 400 kg/m3), and fine/total aggregate ratio (0.35, 0.40, and 0.45). The experimental data were utilized to carry out analysis of variance (ANOVA) and to develop a polynomial regression model for compressive strength in terms of the three design factors considered in this study. The developed statistical model was used to show how optimization of concrete mixtures can be carried out with different possible options. PMID:24688405

  15. Analyses of fine paste ceramics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sabloff, J A

    1980-01-01

    Four chapters are included: history of Brookhaven fine paste ceramics project, chemical and mathematical procedures employed in Mayan fine paste ceramics project, and compositional and archaeological perspectives on the Mayan fine paste ceramics. (DLC)

  16. Fine bed material in pools of natural gravel bed channels

    Treesearch

    Thomas E. Lisle; Sue Hilton

    1999-01-01

    Abstract - Natural gravel bed channels commonly contain a fine mode of sand and fine gravel that fills voids of the bed framework of coarser gravel. If the supply of fine bed material exceeds the storage capacity of framework voids, excess fine material forms surficial patches, which can be voluminous in pools during low flow. Data collected in 34 natural channels in...

  17. The Relationship between Fine-Motor Play and Fine-Motor Skill

    ERIC Educational Resources Information Center

    Marr, Deborah; Cermak, Sharon; Cohn, Ellen S.; Henderson, Anne

    2004-01-01

    This study examined the relationship between free-play choices and fine-motor skill in 4-year-old children attending Head Start. Children with poor fine-motor skill were matched for age and gender with children in the same classroom that exhibited good fine-motor skill. Each pair was observed during free-play sessions to examine the degree of…

  18. Effects of experimental throughfall reduction and soil warming on fine root biomass and its decomposition in a warm temperate oak forest.

    PubMed

    Liu, Yanchun; Liu, Shirong; Wan, Shiqiang; Wang, Jingxin; Wang, Hui; Liu, Kuan

    2017-01-01

    Fine root dynamics play a critical role in regulating carbon (C) cycling in terrestrial ecosystems. Examining responses of fine root biomass and its decomposition to altered precipitation pattern and climate warming is crucial to understand terrestrial C dynamics and its feedback to climate change. Fine root biomass and its decomposition rate were investigated in a warm temperate oak forest through a field manipulation experiment with throughfall reduction and soil warming conducted. Throughfall reduction significantly interacted with soil warming in affecting fine root biomass and its decomposition. Throughfall reduction substantially increased fine root biomass and its decomposition in unheated plots, but negative effects occurred in warmed plots. Soil warming significantly enhanced fine root biomass and its decomposition under ambient precipitation, but the opposite effects exhibited under throughfall reduction. Different responses in fine root biomass among different treatments could be largely attributed to soil total nitrogen (N), while fine root decomposition rate was more depended on microbial biomass C and N. Our observations indicate that decreased precipitation may offset the positive effect of soil warming on fine root biomass and decomposition. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Method for producing dustless graphite spheres from waste graphite fines

    DOEpatents

    Pappano, Peter J [Oak Ridge, TN; Rogers, Michael R [Clinton, TN

    2012-05-08

    A method for producing graphite spheres from graphite fines by charging a quantity of spherical media into a rotatable cylindrical overcoater, charging a quantity of graphite fines into the overcoater thereby forming a first mixture of spherical media and graphite fines, rotating the overcoater at a speed such that the first mixture climbs the wall of the overcoater before rolling back down to the bottom thereby forming a second mixture of spherical media, graphite fines, and graphite spheres, removing the second mixture from the overcoater, sieving the second mixture to separate graphite spheres, charging the first mixture back into the overcoater, charging an additional quantity of graphite fines into the overcoater, adjusting processing parameters like overcoater dimensions, graphite fines charge, overcoater rotation speed, overcoater angle of rotation, and overcoater time of rotation, before repeating the steps until graphite fines are converted to graphite spheres.

  20. [Distribution of fine root biomass of main planting tree species in Loess Plateau, China].

    PubMed

    Jian, Sheng-Qi; Zhao, Chuan-Yan; Fang, Shu-Min; Yu, Kai

    2014-07-01

    The distribution of fine roots of Pinus tabuliformis, Populus tomentosa, Prunus armeniaca, Robinia pseudoacacia, Hippophae rhamnoides, and Caragana korshinskii was investigated by using soil core method and the fine root was defined as root with diameter less than 2 mm. The soil moisture and soil properties were measured. The results showed that in the horizontal direction, the distribution of fine root biomass of P. tabuliformis presented a conic curve, and the fine root biomass of the other species expressed logarithm correlation. Radial roots developed, the fine root biomass were concentrated within the scope of the 2-3 times crown, indicating that trees extended their roots laterally to seek water farther from the tree. In the vertical direction, the fine root biomass decreased with the increasing soil depth. Fine root biomass had significant negative correlation with soil water content and bulk density, while significant positive correlation with organic matter and total N contents.

  1. Measuring the fraction of pool volume filled with fine sediment

    Treesearch

    Sue Hilton; Thomas E. Lisle

    1993-01-01

    The fraction of pool volume filled with fine sediment (usually fine sand to medium gravel) can be a useful index of the sediment supply and substrate habitat of gravel-bed channels. It can be used to evaluate and monitor channel condition and to detect and evaluate sediment sources. This fraction (V*) is the ratio of fine-sediment volume to pool water volume plus fine-...

  2. The volume of fine sediment in pools: An index of sediment supply in gravel-bed streams

    Treesearch

    Thomas E. Lisle; Sue Hilton

    1992-01-01

    Abstract - During waning flood flows in gravel-bed streams, fine-grained bedload sediment (sand and fine gravel) is commonly winnowed from zones of high shear stress, such as riffles, and deposited in pools, where it mantles an underlying coarse layer. As sediment load increases, more fine sediment becomes availabe to fill pools. The volume of fine sediment in pools...

  3. Depressurization-induced fines migration in hydrate-bearing clayey sands: X-ray CT imaging and quantification

    NASA Astrophysics Data System (ADS)

    Han, G.; Kwon, T. H.; Lee, J. Y.

    2016-12-01

    As gas and water flows induced by depressurization of hydrate-bearing sediments exert seepage forces on fines in sediments, such as clay particles, depressurization is reported to accompany the transport of fine particles through sediment pores, i.e., fines migration. Because such fines migration can cause pore clogging, the fines migration is considered as one of the critical phenomena contributing to the transport of fluids among various pore-scale processes associated with depressurization. However, quantification of fines migration during depressurization still remains poorly understood. This study thus investigated fines migration caused by depressurization using X-ray computerized tomography(X-ray CT) imaging. A host sediment was prepared by mixing fine sand with kaolinite clay minerals to achieve 10% mass fraction of fines (less than 75 um). Then, methane hydrate was synthesized in the host clayey sand, and thereafter water was injected to saturate the hydrate-bearing sediment sample. Step-wise depressurization was applied while the produced gas was collected through an outlet fluid port. X-ray CT imaging was conducted on the sediment sample over the courses of the experiment to monitor the sample preparation, hydrate formation, depressurization, and fines migration. Based on the calibration tests, the amount and locations of methane hydrate formed in the sample was estimated, and the gas migration path was also identified. Finally, the spatial distribution of fines after completion of depressurization was first assessed using the obtained X-ray images and then compared with the post-mortem mine-back results.Notably, we found that the middle part of the sample was clogged possibly by fines or by re-formed hydrate, leading to a big pressure difference between the inlet and outlet fluid port of the sample by 3 MPa. Owing to this clogging and the lost in pressure communication, hydrate dissociation first occurred at the bottom half and the hydrate dissociation in the top half part followed later. Our study demonstrates that X-ray CT imaging can be a useful tool to visualize and quantify the fines migration during hydrate depressurization, and our results present an experimental evidence that depressurization can cause pore clogging in sediments containing more than 10% fines fraction.

  4. Usage of Crushed Concrete Fines in Decorative Concrete

    NASA Astrophysics Data System (ADS)

    Pilipenko, Anton; Bazhenova, Sofia

    2017-10-01

    The article is devoted to the questions of usage of crushed concrete fines from concrete scrap for the production of high-quality decorative composite materials based on mixed binder. The main problem in the application of crushed concrete in the manufacture of decorative concrete products is extremely low decorative properties of crushed concrete fines itself, as well as concrete products based on them. However, crushed concrete fines could have a positive impact on the structure of the concrete matrix and could improve the environmental and economic characteristics of the concrete products. Dust fraction of crushed concrete fines contains non-hydrated cement grains, which can be opened in screening process due to the low strength of the contact zone between the hydrated and non-hydrated cement. In addition, the screening process could increase activity of the crushed concrete fines, so it can be used as a fine aggregate and filler for concrete mixes. Previous studies have shown that the effect of the usage of the crushed concrete fines is small and does not allow to obtain concrete products with high strength. However, it is possible to improve the efficiency of the crushed concrete fines as a filler due to the complex of measures prior to mixing. Such measures may include a preliminary mechanochemical activation of the binder (cement binder, iron oxide pigment, silica fume and crushed concrete fines), as well as the usage of polycarboxylate superplasticizers. The development of specific surface area of activated crushed concrete fines ensures strong adhesion between grains of binder and filler during the formation of cement stone matrix. The particle size distribution of the crushed concrete fines could achieve the densest structure of cement stone matrix and improve its resistance to environmental effects. The authors examined the mechanisms of structure of concrete products with crushed concrete fines as a filler. The results of studies of the properties of the crushed concrete fines were provided. It is shown that the admixture of the crushed concrete fines has little effect on the colour characteristics of the decorative concrete products. The preferred options to improve the surfaces of decorative concrete are also proposed.

  5. Response of the Fine Root Production, Phenology, and Turnover Rate of Six Shrub Species from a Subtropical Forest to a Soil Moisture Gradient and Shading

    NASA Astrophysics Data System (ADS)

    Fu, X.; Dai, X.; Wang, H.

    2015-12-01

    Knowledge of the fine root dynamics of different life forms in forest ecosystems is critical to understanding how the overall belowground carbon cycling is affected by climate change. However, our current knowledge regarding how endogenous or exogenous factors regulate the root dynamics of understory vegetation is limited. We selected a suite of study sites representing different habitats with gradients of soil moisture and solar radiation (shading or no shading). We assessed the fine root production phenology, the total fine root production, and the turnover among six understory shrub species in a subtropical climate, and examined the responses of the fine root dynamics to gradients in the soil moisture and solar radiation. The shrubs included three evergreen species, Loropetalum chinense, Vaccinium bracteatum, and Adinandra millettii, and three deciduous species, Serissa serissoides, Rubus corchorifolius, and Lespedeza davidii. We observed that variations in the annual fine root production and turnover among species were significant in the deciduous group but not in the evergreen group. Notably, V. bracteatum and S. serissoides presented the greatest responses in terms of root phenology to gradients in the soil moisture and shading: high-moisture habitat led to a decrease and shade led to an increase in fine root production during spring. Species with smaller fine roots of the 1st+2nd-order diameter presented more sensitive responses in terms of fine root phenology to a soil moisture gradient. Species with a higher fine root nitrogen-to -carbon ratio exhibited more sensitive responses in terms of fine root annual production to shading. Soil moisture and shading did not change the annual fine root production as much as the turnover rate. The fine root dynamics of some understory shrubs varied significantly with soil moisture and solar radiation status and may be different from tree species. Our results emphasize the need to study the understory fine root dynamics in the achievement of a complete understanding of the overall belowground carbon cycling in a forest ecosystem, particularly ecosystems in which the understory fine root highly contributes to the belowground biomass.

  6. Fine root biomass in relation to site and stand characteristics in Norway spruce and Scots pine stands.

    PubMed

    Helmisaari, Heljä-Sisko; Derome, John; Nöjd, Pekka; Kukkola, Mikko

    2007-10-01

    Variations in fine root biomass of trees and understory in 16 stands throughout Finland were examined and relationships to site and stand characteristics determined. Norway spruce fine root biomass varied between 184 and 370 g m(-2), and that of Scots pine ranged between 149 and 386 g m(-2). In northern Finland, understory roots and rhizomes (< 2 mm diameter) accounted for up to 50% of the stand total fine root biomass. Therefore, the fine root biomass of trees plus understory was larger in northern Finland in stands of both tree species, resulting in a negative relationship between fine root biomass and the temperature sum and a positive relationship between fine root biomass and the carbon:nitrogen ratio of the soil organic layer. The foliage:fine root ratio varied between 2.1 and 6.4 for Norway spruce and between 0.8 and 2.2 for Scots pine. The ratio decreased for both Norway spruce and Scots pine from south to north, as well as from fertile to more infertile site types. The foliage:fine root ratio of Norway spruce was related to basal area and stem surface area. The strong positive correlations of these three parameters with fine root nitrogen concentration implies that more fine roots are needed to maintain a certain amount of foliage when nutrient availability is low. No significant relationships were found between stand parameters and fine root biomass at the stand level, but the relationships considerably improved when both fine root biomass and stand parameters were calculated for the mean tree in the stand. When the northern and southern sites were analyzed separately, fine root biomass per tree of both species was significantly correlated with basal area and stem surface area per tree. Basal area, stem surface area and stand density can be estimated accurately and easily. Thus, our results may have value in predicting fine root biomass at the tree and stand level in boreal Norway spruce and Scots pine forests.

  7. Home range establishment and utilization by reintroduced lions (Panthera leo) in a small South African wildlife reserve.

    PubMed

    Yiu, Sze-Wing; Parrini, Francesca; Karczmarski, Leszek; Keith, Mark

    2017-07-01

    Understanding of animal spatial behavior is essential for informed management decisions. In southern Africa, reintroduction of lions (Panthera leo) to small reserves (<1000 km 2 ) has increased since the early 2000s, however studies on their ranging behavior in these enclosed systems remain lacking. We applied Time Local Convex Hull (T-LoCoH) methods to study the home range establishment and utilization of 11 lions reintroduced to Dinokeng Game Reserve, South Africa, during 2011 through 2014. Lions established home ranges close to their release sites and during the following 3 years their home range sizes continued to increase, but in each individual case the size remained smaller than half of the reserve area (<70 km 2 ). Space use strategies differed between the core and the entire home range, with higher frequency of visits found in core areas. Exceptionally high rates (>60 separate visits) around the largest dam and along rivers suggest the importance of water and its surrounding vegetation in the lions' space utilization pattern. The home range size did not differ with season or sex of the individuals, whereas shifts in locations of home ranges revealed differences in the response of the 2 sexes to territorial conflicts and management interventions. Our study shows a dynamic home range utilization pattern and highlights the importance of both fine-scale space use patterns (frequency and duration of visits) and broad-scale home range changes in understanding the ranging behavior of reintroduced animals. © 2016 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

  8. Effects of cafestol and kahweol from coffee grounds on serum lipids and serum liver enzymes in humans.

    PubMed

    Urgert, R; Schulz, A G; Katan, M B

    1995-01-01

    The diterpenes cafestol and kahweol are present in unfiltered coffee in oil droplets and floating fines. They elevate serum cholesterol and alanine aminotransferase (ALT). We measured fines in coffee brews, and examined diterpene availability from spent grounds in healthy volunteers. Turkish or Scandinavian boiled coffee contained 2-5 g fines/L and French press coffee contained 1.5 g fines/L. An intake of 8 g fine grounds/d for 3 wk increased cholesterol by 0.65 mmol/L (95% CI 0.41-0.89 mmol/L) and ALT by 18 U/L (95% CI 4-32 U/L) relative to control subjects (n = 7/group). In a crossover study (n = 15), mean serum cholesterol was 4.9 mmol/L after consumption of both fine and coarse grounds for 10 d (P = 0.43). Serum ALT activities were 29 U/L on fine and 21 U/L on coarse grounds (P = 0.02). Floating fines could contribute substantially to the hyperlipidemic and ALT-elevating effect of unfiltered coffee. Diterpene measurements in coffee brews should include the contribution of fines.

  9. Modelling excitonic-energy transfer in light-harvesting complexes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kramer, Tobias; Kreisbeck, Christoph

    The theoretical and experimental study of energy transfer in photosynthesis has revealed an interesting transport regime, which lies at the borderline between classical transport dynamics and quantum-mechanical interference effects. Dissipation is caused by the coupling of electronic degrees of freedom to vibrational modes and leads to a directional energy transfer from the antenna complex to the target reaction-center. The dissipative driving is robust and does not rely on fine-tuning of specific vibrational modes. For the parameter regime encountered in the biological systems new theoretical tools are required to directly compare theoretical results with experimental spectroscopy data. The calculations require tomore » utilize massively parallel graphics processor units (GPUs) for efficient and exact computations.« less

  10. Association Analysis in Rice: From Application to Utilization

    PubMed Central

    Zhang, Peng; Zhong, Kaizhen; Shahid, Muhammad Qasim; Tong, Hanhua

    2016-01-01

    Association analysis based on linkage disequilibrium (LD) is an efficient way to dissect complex traits and to identify gene functions in rice. Although association analysis is an effective way to construct fine maps for quantitative traits, there are a few issues which need to be addressed. In this review, we will first summarize type, structure, and LD level of populations used for association analysis of rice, and then discuss the genotyping methods and statistical approaches used for association analysis in rice. Moreover, we will review current shortcomings and benefits of association analysis as well as specific types of future research to overcome these shortcomings. Furthermore, we will analyze the reasons for the underutilization of the results within association analysis in rice breeding. PMID:27582745

  11. Targeting polyamine metabolism for cancer therapy and prevention

    PubMed Central

    Murray-Stewart, Tracy R.; Woster, Patrick M.; Casero, Robert A.

    2017-01-01

    The chemically simple, biologically complex eukaryotic polyamines, spermidine and spermine, are positively charged alkylamines involved in many crucial cellular processes. Along with their diamine precursor putrescine, their normally high intracellular concentrations require fine attenuation by multiple regulatory mechanisms to keep these essential molecules within strict physiologic ranges. Since the metabolism of and requirement for polyamines are frequently dysregulated in neoplastic disease, the metabolic pathway and functions of polyamines provide rational drug targets; however, these targets have been difficult to exploit for chemotherapy. It is the goal of this article to review the latest findings in the field that demonstrate the potential utility of targeting the metabolism and function of polyamines as strategies for both chemotherapy and, possibly more importantly, chemoprevention. PMID:27679855

  12. Method of producing particulate-reinforced composites and composites produced thereby

    DOEpatents

    Han, Qingyou; Liu, Zhiwei

    2013-12-24

    A process for producing particle-reinforced composite materials through utilization of an in situ reaction to produce a uniform dispersion of a fine particulate reinforcement phase. The process includes forming a melt of a first material, and then introducing particles of a second material into the melt and subjecting the melt to high-intensity acoustic vibration. A chemical reaction initiates between the first and second materials to produce reaction products in the melt. The reaction products comprise a solid particulate phase, and the high-intensity acoustic vibration fragments and/or separates the reaction products into solid particles that are dispersed in the melt and are smaller than the particles of the second material. Also encompassed are particle-reinforced composite materials produced by such a process.

  13. Recent Advances in the Synthesis, Characterization and Application of Zn+-containing Heterogeneous Catalysts.

    PubMed

    Chen, Guangbo; Zhao, Yufei; Shang, Lu; Waterhouse, Geoffrey I N; Kang, Xiaofeng; Wu, Li-Zhu; Tung, Chen-Ho; Zhang, Tierui

    2016-07-01

    Monovalent Zn + (3d 10 4s 1 ) systems possess a special electronic structure that can be exploited in heterogeneous catalysis and photocatalysis, though it remains challenge to synthesize Zn + -containing materials. By careful design, Zn + -related species can be synthesized in zeolite and layered double hydroxide systems, which in turn exhibit excellent catalytic potential in methane, CO and CO 2 activation. Furthermore, by utilizing advanced characterization tools, including electron spin resonance, X-ray absorption fine structure and density functional theory calculations, the formation mechanism of the Zn + species and their structure-performance relationships can be understood. Such advanced characterization tools guide the rational design of high-performance Zn + -containing catalysts for efficient energy conversion.

  14. Medical talent management: a model for physician deployment.

    PubMed

    Brightman, Baird

    2007-01-01

    This article aims to provide a focused cost-effective method for triaging physicians into appropriate non-clinical roles to benefit both doctors and healthcare organizations. Reviews a validated career-planning process and customize it for medical talent management. A structured career assessment can differentiate between different physician work styles and direct medical talent into best-fit positions. This allows healthcare organizations to create a more finely tuned career ladder than the familiar "in or out" binary choice. PRACTICAL IMPLICATIONS--Healthcare organizations can invest in cost-effective processes for the optimal utilization of their medical talent. Provides a new use for a well-validated career assessment and planning system. The actual value of this approach should be studied using best-practices in ROI research.

  15. Bubble Point Measurements with Liquid Methane of a Screen Capillary Liquid Acquisition Device

    NASA Technical Reports Server (NTRS)

    Jurns, John M.; McQuillen, John B.

    2009-01-01

    Liquid acquisition devices (LADs) can be utilized within a propellant tank in space to deliver single-phase liquid to the engine in low gravity. One type of liquid acquisition device is a screened gallery whereby a fine mesh screen acts as a bubble filter and prevents the gas bubbles from passing through until a crucial pressure differential condition across the screen, called the bubble point, is reached. This paper presents data for LAD bubble point data in liquid methane (LCH4) for stainless steel Dutch twill screens with mesh sizes of 325 by 2300 and 200 by 1400 wires per inch. Data is presented for both saturated and sub-cooled LCH4, and is compared with predicted values.

  16. Recent Advances in the Synthesis, Characterization and Application of Zn+‐containing Heterogeneous Catalysts

    PubMed Central

    Chen, Guangbo; Zhao, Yufei; Shang, Lu; Waterhouse, Geoffrey I. N.; Kang, Xiaofeng; Wu, Li‐Zhu; Tung, Chen‐Ho

    2016-01-01

    Monovalent Zn+ (3d104s1) systems possess a special electronic structure that can be exploited in heterogeneous catalysis and photocatalysis, though it remains challenge to synthesize Zn+‐containing materials. By careful design, Zn+‐related species can be synthesized in zeolite and layered double hydroxide systems, which in turn exhibit excellent catalytic potential in methane, CO and CO2 activation. Furthermore, by utilizing advanced characterization tools, including electron spin resonance, X‐ray absorption fine structure and density functional theory calculations, the formation mechanism of the Zn+ species and their structure‐performance relationships can be understood. Such advanced characterization tools guide the rational design of high‐performance Zn+‐containing catalysts for efficient energy conversion. PMID:27818902

  17. Dispersion engineering in metamaterials and metasurfaces

    NASA Astrophysics Data System (ADS)

    Li, Xiong; Pu, Mingbo; Ma, Xiaoliang; Guo, Yinghui; Gao, Ping; Luo, Xiangang

    2018-02-01

    Dispersion engineering is essential for spectral utilization in electromagnetic systems. However, it is difficult to manage the dispersions in both natural materials and traditional electromagnetic waveguides since they are tightly related to fine structures of atoms, molecules and causality. The emergence of metamaterials and metasurfaces, which are made of subwavelength inclusions offers tremendous freedom to manipulate the electromagnetic parameters of materials and modes. Here, we review the basic principles, practical applications and recent advancements of the dispersion engineering in metadevices. The contributions of dispersion management in metadevice-based super-resolution imaging/nanolithography systems, planar functional devices, as well as the broadband perfect absorbers/polarization converters are discussed in depth. The challenges faced by this field as well as future developing trends are also presented in the conclusions.

  18. Coarse-to-fine markerless gait analysis based on PCA and Gauss-Laguerre decomposition

    NASA Astrophysics Data System (ADS)

    Goffredo, Michela; Schmid, Maurizio; Conforto, Silvia; Carli, Marco; Neri, Alessandro; D'Alessio, Tommaso

    2005-04-01

    Human movement analysis is generally performed through the utilization of marker-based systems, which allow reconstructing, with high levels of accuracy, the trajectories of markers allocated on specific points of the human body. Marker based systems, however, show some drawbacks that can be overcome by the use of video systems applying markerless techniques. In this paper, a specifically designed computer vision technique for the detection and tracking of relevant body points is presented. It is based on the Gauss-Laguerre Decomposition, and a Principal Component Analysis Technique (PCA) is used to circumscribe the region of interest. Results obtained on both synthetic and experimental tests provide significant reduction of the computational costs, with no significant reduction of the tracking accuracy.

  19. Automation of experimental research of waveguide paths induction soldering

    NASA Astrophysics Data System (ADS)

    Tynchenko, V. S.; Petrenko, V. E.; Kukartsev, V. V.; Tynchenko, V. V.; Antamoshkin, O. A.

    2018-05-01

    The article presents an automated system of experimental studies of the waveguide paths induction soldering process. The system is a part of additional software for a complex of automated control of the technological process of induction soldering of thin-walled waveguide paths from aluminum alloys, expanding its capabilities. The structure of the software product, the general appearance of the controls and the potential application possibilities are presented. The utility of the developed application by approbation in a series of field experiments was considered and justified. The application of the experimental research system makes it possible to improve the process under consideration, providing the possibility of fine-tuning the control regulators, as well as keeping the statistics of the soldering process in a convenient form for analysis.

  20. Comprehensive assessment of toxic emissions from coal-fired power plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, T D; Schmidt, C E; Radziwon, A S

    1991-01-01

    The Pittsburgh Energy Technology Center (PETC) of the US Department of Energy (DOE) has two current investigations, initiated before passage of the Clean Air Act Amendment (CAAA), that will determine the air toxic emissions from coal-fired electric utilities. DOE has contracted with Battelle Memorial Institute and Radian corporation to conduct studies focusing on the potential air toxics, both organic and inorganic, associated with different size fractions of fine particulate matter emitted from power plant stacks. Table 2 indicates the selected analytes to be investigated during these studies. PETC is also developing guidance on the monitoring of Hazardous Air Pollutants (HAPS)more » to be incorporated in the Environmental Monitoring plans for the demonstration projects in its Clean Coal Technology Program.« less

  1. The process of gas-dynamic design of pneumatic braking system using the baseline compressor

    NASA Astrophysics Data System (ADS)

    Novikova, Y.; Popov, G.; Goriachkin, E.; Baturin, O.; Zubanov, V.

    2017-08-01

    The article presents the results of work on the design of the air brake for testing of industrial gas turbine engines with free turbine. Designing of the air brake was performed on the basis of existing units using the program CFD - simulation Numeca FineTurbo. During the design the air brake arrangement was determined, which allows to utilize the required power to the shaft of the free turbine, increases stall margin of the air brake by waisting of the meridional flow channel. It was also made designing of the outlet guide vane to remove the residual twist. Unified nozzle also was designed to provide the air brake work at necessary points on the characteristic.

  2. Method of producing particulate-reinforced composites and composites produced thereby

    DOEpatents

    Han, Qingyou; Liu, Zhiwei

    2015-12-29

    A process for producing particle-reinforced composite materials through utilization of an in situ reaction to produce a uniform dispersion of a fine particulate reinforcement phase. The process includes forming a melt of a first material, and then introducing particles of a second material into the melt and subjecting the melt to high-intensity acoustic vibration. A chemical reaction initiates between the first and second materials to produce reaction products in the melt. The reaction products comprise a solid particulate phase, and the high-intensity acoustic vibration fragments and/or separates the reaction products into solid particles that are dispersed in the melt and are smaller than the particles of the second material. Also encompassed are particle-reinforced composite materials produced by such a process.

  3. Method of producing particulate-reinforced composites and composties produced thereby

    DOEpatents

    Han, Qingyou; Liu, Zhiwei

    2013-12-24

    A process for producing particle-reinforced composite materials through utilization of an in situ reaction to produce a uniform dispersion of a fine particulate reinforcement phase. The process includes forming a melt of a first material, and then introducing particles of a second material into the melt and subjecting the melt to high-intenisty acoustic vibration. A chemical reaction initiates between the first and second materials to produce reaction products in the melt. The reaciton products comprise a solide particulate phase, and the high-intensity acoustic vibration fragments and/or separates the reaction products into solid particles that are dispersed in the melt and are smaller than the particles of the second material. Also encompassed are particles-reinforced composite materials produced by such a process.

  4. Regulatory RNA-assisted genome engineering in microorganisms.

    PubMed

    Si, Tong; HamediRad, Mohammad; Zhao, Huimin

    2015-12-01

    Regulatory RNAs are increasingly recognized and utilized as key modulators of gene expression in diverse organisms. Thanks to their modular and programmable nature, trans-acting regulatory RNAs are especially attractive in genome-scale applications. Here we discuss the recent examples in microbial genome engineering implementing various trans-acting RNA platforms, including sRNA, RNAi, asRNA and CRISRP-Cas. In particular, we focus on how the scalable and multiplex nature of trans-acting RNAs has been used to tackle the challenges in creating genome-wide and combinatorial diversity for functional genomics and metabolic engineering applications. Advances in computational design and context-dependent regulation are also discussed for their contribution in improving fine-tuning capabilities of trans-acting RNAs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Supercritical crystallization: The RESs-process and the GAS-process

    NASA Astrophysics Data System (ADS)

    Berends, Edwin M.

    1994-09-01

    This Doctoral Ph.D. thesis describes the development of two novel crystallization processes utilizing supercritical fluids either as a solvent, the RESS-process, or as an anti-solvent, the GAS-process. In th RESS-process precipitation of the solute is performed by expansion of the solution over a nozzle to produce ultra-fine, monodisperse particles without any solvent inclusions. In the GAS-process a high pressure gas is dissolved into the liquid phase solvent, where it causes a volumetric expansion of this liquid solvent and lowers the equilibrium solubility. Particle size, particle size distribution and other particle characteristics such as their shape, internal structure and the residual amount of solvent in the particles are expected to be influenced by the liquid phase expansion profile.

  6. Carbon phenolic heat shields for Jupiter/Saturn/Uranus entry probes

    NASA Technical Reports Server (NTRS)

    Mezines, S.

    1974-01-01

    Carbon phenolic heat shield technology is reviewed. Heat shield results from the outer planetary probe mission studies are summarized along with results of plasma jet testing of carbon phenolic conducted in a ten megawatt facility. Missile flight data is applied to planetary entry conditions. A carbon phenolic heat shield material is utilized and tailored to accommodate each of the probe missions. An integral heat shield approach is selected over in order to eliminate a high temperature interface problem and permit direct bonding of the carbon phenolic to the structural honeycomb sandwich. The sandwich is filled with a very fine powder to minimize degradation of its insulation properties by the high conductive hydrogen/helium gases during the long atmospheric descent phase.

  7. Controlled release from drug microparticles via solventless dry-polymer coating.

    PubMed

    Capece, Maxx; Barrows, Jason; Davé, Rajesh N

    2015-04-01

    A novel solvent-less dry-polymer coating process employing high-intensity vibrations avoiding the use of liquid plasticizers, solvents, binders, and heat treatments is utilized for the purpose of controlled release. The main hypothesis is that such process having highly controllable processing intensity and time may be effective for coating particularly fine particles, 100 μm and smaller via exploiting particle interactions between polymers and substrates in the dry state, while avoiding breakage yet achieving conformal coating. The method utilizes vibratory mixing to first layer micronized polymer onto active pharmaceutical ingredient (API) particles by virtue of van der Waals forces and to subsequently mechanically deform the polymer into a continuous film. As a practical example, ascorbic acid and ibuprofen microparticles, 50-500 μm, are coated with the polymers polyethylene wax or carnauba wax, a generally recognized as safe material, resulting in controlled release on the order of seconds to hours. As a novelty, models are utilized to describe the coating layer thickness and the controlled-release behavior of the API, which occurs because of a diffusion-based mechanism. Such modeling would allow the design and control of the coating process with application for the controlled release of microparticles, particularly those less than 100 μm, which are difficult to coat by conventional solvent coating methods. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

  8. Development of Advanced Coatings for Laser Modifications Through Process and Materials Simulation

    NASA Astrophysics Data System (ADS)

    Martukanitz, R. P.; Babu, S. S.

    2004-06-01

    A simulation-based system is currently being constructed to aid in the development of advanced coating systems for laser cladding and surface alloying. The system employs loosely coupled material and process models that allow rapid determination of material compatibility over a wide range of processing conditions. The primary emphasis is on the development and identification of composite coatings for improved wear and corrosion resistance. The material model utilizes computational thermodynamics and kinetic analysis to establish phase stability and extent of diffusional reactions that may result from the thermal response of the material during virtual processing. The process model is used to develop accurate thermal histories associated with the laser surface modification process and provides critical input for the non-isothermal materials simulations. These techniques were utilized to design a laser surface modification experiment that utilized the addition of stainless steel alloy 431 and TiC produced using argon and argon and nitrogen shielding. The deposits representing alloy 431 and TiC powder produced in argon resulted in microstructures retaining some TiC particles and an increase in hardness when compared to deposits produced using only the 431 powder. Laser deposits representing alloy 431 and TiC powder produced with a mixture of argon and nitrogen shielding gas resulted in microstructures retaining some TiC particles, as well as fine precipitates of Ti(CN) formed during cooling and a further increase in hardness of the deposit.

  9. Biotechnology of non-Saccharomyces yeasts--the ascomycetes.

    PubMed

    Johnson, Eric A

    2013-01-01

    Saccharomyces cerevisiae and several other yeast species are among the most important groups of biotechnological organisms. S. cerevisiae and closely related ascomycetous yeasts are the major producer of biotechnology products worldwide, exceeding other groups of industrial microorganisms in productivity and economic revenues. Traditional industrial attributes of the S. cerevisiae group include their primary roles in food fermentations such as beers, cider, wines, sake, distilled spirits, bakery products, cheese, sausages, and other fermented foods. Other long-standing industrial processes involving S. cerevisae yeasts are production of fuel ethanol, single-cell protein (SCP), feeds and fodder, industrial enzymes, and small molecular weight metabolites. More recently, non-Saccharomyces yeasts (non-conventional yeasts) have been utilized as industrial organisms for a variety of biotechnological roles. Non-Saccharomyces yeasts are increasingly being used as hosts for expression of proteins, biocatalysts and multi-enzyme pathways for the synthesis of fine chemicals and small molecular weight compounds of medicinal and nutritional importance. Non-Saccharomyces yeasts also have important roles in agriculture as agents of biocontrol, bioremediation, and as indicators of environmental quality. Several of these products and processes have reached commercial utility, while others are in advanced development. The objective of this mini-review is to describe processes currently used by industry and those in developmental stages and close to commercialization primarily from non-Saccharomyces yeasts with an emphasis on new opportunities. The utility of S. cerevisiae in heterologous production of selected products is also described.

  10. FINE PARTICLE EMISSIONS INFORMATION SYSTEM: SUMMARY REPORT (SUMMER 1976)

    EPA Science Inventory

    The report summarizes the initial loading of data into the Fine Particle Emissions Information System (FPEIS), a computerized database on primary fine particle emissions to the atmosphere from stationary sources, designed to assist engineers and scientists engaged in fine particl...

  11. 16. Coke 'fines' bin at Furnace D. After delivery to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Coke 'fines' bin at Furnace D. After delivery to the trestle bins, the coke was screened and the coke 'fines' or breeze, were transported by conveyor to the coke fines bins where it was collected and leaded into dump trucks. The coke fines were then sold for fuel to a sinter plant in Lorain, Ohio. - Central Furnaces, 2650 Broadway, east bank of Cuyahoga River, Cleveland, Cuyahoga County, OH

  12. A global Fine-Root Ecology Database to address below-ground challenges in plant ecology

    DOE PAGES

    Iversen, Colleen M.; McCormack, M. Luke; Powell, A. Shafer; ...

    2017-02-28

    Variation and tradeoffs within and among plant traits are increasingly being harnessed by empiricists and modelers to understand and predict ecosystem processes under changing environmental conditions. And while fine roots play an important role in ecosystem functioning, fine-root traits are underrepresented in global trait databases. This has hindered efforts to analyze fine-root trait variation and link it with plant function and environmental conditions at a global scale. This Viewpoint addresses the need for a centralized fine-root trait database, and introduces the Fine-Root Ecology Database (FRED, http://roots.ornl.gov) which so far includes > 70 000 observations encompassing a broad range of rootmore » traits and also includes associated environmental data. FRED represents a critical step toward improving our understanding of below-ground plant ecology. For example, FRED facilitates the quantification of variation in fine-root traits across root orders, species, biomes, and environmental gradients while also providing a platform for assessments of covariation among root, leaf, and wood traits, the role of fine roots in ecosystem functioning, and the representation of fine roots in terrestrial biosphere models. There has been a continued input of observations into FRED to fill gaps in trait coverage will improve our understanding of changes in fine-root traits across space and time.« less

  13. A global Fine-Root Ecology Database to address below-ground challenges in plant ecology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Iversen, Colleen M.; McCormack, M. Luke; Powell, A. Shafer

    Variation and tradeoffs within and among plant traits are increasingly being harnessed by empiricists and modelers to understand and predict ecosystem processes under changing environmental conditions. And while fine roots play an important role in ecosystem functioning, fine-root traits are underrepresented in global trait databases. This has hindered efforts to analyze fine-root trait variation and link it with plant function and environmental conditions at a global scale. This Viewpoint addresses the need for a centralized fine-root trait database, and introduces the Fine-Root Ecology Database (FRED, http://roots.ornl.gov) which so far includes > 70 000 observations encompassing a broad range of rootmore » traits and also includes associated environmental data. FRED represents a critical step toward improving our understanding of below-ground plant ecology. For example, FRED facilitates the quantification of variation in fine-root traits across root orders, species, biomes, and environmental gradients while also providing a platform for assessments of covariation among root, leaf, and wood traits, the role of fine roots in ecosystem functioning, and the representation of fine roots in terrestrial biosphere models. There has been a continued input of observations into FRED to fill gaps in trait coverage will improve our understanding of changes in fine-root traits across space and time.« less

  14. Tests for Plastic Fines in Aggregates Related to Stripping in Asphalt Paving Mixtures

    DOT National Transportation Integrated Search

    1988-03-01

    This study was undertaken for determining the best aggregate test method that indicates the presence of detrimental plastic fines in the fine aggregate, which may induce stripping in hot mix asphalt (HMA) mixtures. Ten fine aggregates representing a ...

  15. Effectiveness of double fines as a speed control measure in safety corridors.

    DOT National Transportation Integrated Search

    2002-12-01

    The use of elevated traffic fines, and specifically doubling of applicable traffic fines under certain conditions, is widely used in Oregon as a speed control measure. Double fines have applied to safety corridors in Oregon since 1999. Double f...

  16. M553 sphere forming experiment: Pure nickel specimen evaluation

    NASA Technical Reports Server (NTRS)

    Johnson, P. C.; Peters, E. T.

    1973-01-01

    A region or cap of very fine two-dimensional surface growth structure was observed at the top of three of the six pure nickel flight specimens. Such two-dimensional surface growth structures have been observed both on the ground-based specimens and on other surface areas of the flight specimens. However, the fine structures observed on the three flight samples are at least an order of magnitude finer than those previously observed, and resemble similar localized, fine, two-dimensional surface structures observed in both ground and flight specimens for the nickel alloys. The two-dimensional growth areas consist primarily of fine equiaxed grains, specimen SL-2.6, fine dendrites, specimen SL-2.5, or a core of fine equiaxed grains surrounded by a ring of fine dendrites, specimen SL-1.9.

  17. Channel Maintenance and Flushing Flows for the Klamath River Below Iron Gate Dam, California

    USGS Publications Warehouse

    Holmquist-Johnson, Cristopher L.; Milhous, Robert T.

    2010-01-01

    The Klamath River is a major river in northern California and southern Oregon. Iron Gate Dam divides the river into the two subunits where there is a significant change in utilization of the river. Downstream of Iron Gate Dam, the river is very important for the propagation of salmon. To address concerns relating to substrate conditions in the mainstem Klamath River below Iron Gate Dam, the Arcata, California, office of the U.S. Fish and Wildlife Service contracted with the U.S. Geological Survey (USGS) to determine flushing flows required to improve and maintain quality spawning and rearing habitats for salmon, and to reduce the abundance of preferred habitats of the polychaete worm suspected of being the intermediate host for Ceratomyxa shasta, a species of bacteria that infects fish. Historically, the river has had the capacity to move sediment just below Iron Gate Reservoir, but there have been periods when the capacity was very low. The results indicate that if the future is more like the pre-1961 period (low transport capacity) than the more recent period, there will be significant sediment issues in the Klamath River below Iron Gate Dam. It seems that during normal or wet years, winter months, and periods of high flow, sediments are flushed either downstream or deposited on higher surfaces. The recent drought conditions during 2000-2005 probably resulted in extensive fine-grained sedimentation along the river, which in turn may have caused increased establishment of aquatic vegetation and increased concentrations of C. shasta. It appears that releases from Iron Gate Dam as far downstream as Seiad Valley are important in maintaining flow conditions to flush the fines and clean the gravels in the river during summer months, or during drought years. Sediment transport studies indicate that supplemental flows during dry or drought conditions may provide some flushing flows in reaches downstream of the dam. For purposes of flushing fine sediments during drought years or dry summer months, flows in the range of 2,500-5,000 cubic feet per second during a period of days may be necessary. Providing these types of flows in a manner similar to a storm pulse would provide the best opportunity to flush the fines and clean some of the gravels given the upper ranges of flows are achieved.

  18. Friction and Wear Properties of As-Deposited and Carbon Ion-Implanted Diamond Films

    NASA Technical Reports Server (NTRS)

    Miyoshi, Kazuhisa

    1996-01-01

    Recent work on the friction and wear properties of as-deposited and carbon ion-implanted diamond films was reviewed. Diamond films were produced by the microwave plasma chemical vapor deposition (CVD) technique. Diamond films with various grain sizes and surface roughnesses were implanted with carbon ions at 60 keV ion energy, resulting in a dose of 1.2 x 10(exp 17) carbon ions per cm(exp 2). Various analytical techniques, including Raman spectroscopy, proton recoil analysis, Rutherford backscattering, transmission and scanning electron microscopy, X-ray photoelectron spectroscopy, and X-ray diffraction, were utilized to characterize the diamond films. Sliding friction experiments were conducted with a polished natural diamond pin in contact with diamond films in the three environments: humid air (40% relative humidity), dry nitrogen (less than 1 percent relative humidity), and ultrahigh vacuum (10(exp -7) Pa). The CVD diamond films indeed have friction and wear properties similar to those of natural diamond in the three environments. The as-deposited, fine-grain diamond films can be effectively used as self-lubricating, wear-resistant coatings that have low coefficients of friction (0.02 to 0.04) and low wear rates (10(exp -7) to lO(exp -8) mm(exp 3) N(exp -1) m(exp -1)) in both humid air and dry nitrogen. However, they have high coefficients of friction (1.5 to 1.7) and a high wear rate (10(exp -4) mm(exp 7) N(exp -1) m(exp -1)) in ultrahigh vacuum. The carbon ion implantation produced a thin surficial layer (less than 0.1 micron thick) of amorphous, non-diamond carbon on the diamond films. In humid air and dry nitrogen, the ion-implanted, fine and coarse-grain diamond films have a low coefficient of friction (around 0.1) and a low wear rate (10(exp -7) mm(exp 3) N(exp -1) m(exp-1)). Even in ultrahigh vacuum, the presence of the non-diamond carbon layer reduced the coefficient of friction of fine-grain diamond films to 0.1 or lower and the wear rate to 10(exp -6) mm(exp 3) N(exp -1) m(exp -1). Thus, the carbon ion-implanted, fine-grain diamond films can be effectively used as wear-resistant, self-lubricating coatings not only in air and dry nitrogen, but also in ultrahigh vacuum.

  19. Effects of Inundation, Nutrient Availability and Plant Species Diversity on Fine Root Mass and Morphology Across a Saltmarsh Flooding Gradient

    PubMed Central

    Redelstein, Regine; Dinter, Thomas; Hertel, Dietrich; Leuschner, Christoph

    2018-01-01

    Saltmarsh plants are exposed to multiple stresses including tidal inundation, salinity, wave action and sediment anoxia, which require specific root system adaptations to secure sufficient resource capture and firm anchorage in a temporary toxic environment. It is well known that many saltmarsh species develop large below-ground biomass (roots and rhizomes) but relations between fine roots, in particular, and the abiotic conditions in salt marshes are widely unknown. We studied fine root mass (<2 mm in diameter), fine root depth distribution and fine root morphology in three typical communities (Spartina anglica-dominated pioneer zone, Atriplex portulacoides-dominated lower marsh, Elytrigia atherica-dominated upper marsh) across elevational gradients in two tidal salt marshes of the German North Sea coast [a mostly sandy marsh on a barrier island (Spiekeroog), and a silty-clayey marsh on the mainland coast (Westerhever)]. Fine root mass in the 0–40 cm profile ranged between 750 and 2,500 g m−2 in all plots with maxima at both sites in the lower marsh with intermediate inundation frequency and highest plant species richness indicating an effect of biodiversity on fine root mass. Fine root mass and, even more, total fine root surface area (maximum 340 m2 m−2) were high compared to terrestrial grasslands, and were greater in the nutrient-poorer Spiekeroog marsh. Fine root density showed only a slight or no decrease toward 40 cm depth. We conclude that the standing fine root mass and morphology of these salt marshes is mainly under control of species identity and nutrient availability, but species richness is especially influential. The plants of the pioneer zone and lower marsh possess well adapted fine roots and large standing root masses despite the often water-saturated sediment. PMID:29467778

  20. Choice of fineness of pulverized coal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    E.N. Tolchinskii; A.Yu. Lavrent'ev

    2002-11-15

    Various methods for choosing the fineness of power plant coal dust are reviewed and analytical expressions for determining the fineness are presented. It is shown that the use of the yield of combustibles as a parameter is not always suitable for evaluating the fineness of pulverized coal. The suggested expression for computing the fineness bears composite parameters that allow for the heat value of the volatiles and for the internal surface of the fuel particles.

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