V-22 Osprey Tilt-Rotor Aircraft: Background and Issues for Congress

DTIC Science & Technology

2009-07-14

of the rotors (rotor disk not perpendicular to spindle shaft ) by not producing the commands requested by the pilot’s controls positions. This tends...conventional helicopter while also having the long-range cruise abilities of a twin turboprop aircraft.”1 The MV-22 is designed to transport 24 fully...are in their avionics. The CV- 22 is designed to carry 18 troops, with auxiliary fuel tanks increasing the aircraft’s combat radius to about 500 miles

V-22 Osprey Tilt-Rotor Aircraft: Background and Issues for Congress

DTIC Science & Technology

2009-10-20

of the rotors (rotor disk not perpendicular to spindle shaft ) by not producing the commands requested by the pilot’s controls positions. This tends...a conventional helicopter while also having the long-range cruise abilities of a twin turboprop aircraft.”1 The MV-22 is designed to transport 24...variants are in their avionics. The CV- 22 is designed to carry 18 troops, with auxiliary fuel tanks increasing the aircraft’s combat radius to about 500

Pharmaceuticals in water, fish and osprey nestlings in Delaware River and Bay

USGS Publications Warehouse

Bean, Thomas G.; Rattner, Barnett A.; Lazarus, Rebecca S.; Day, Daniel D.; Burket, S. Rebekah; Brooks, Bryan W.; Haddad, Samuel P.; Bowerman, William W.

2018-01-01

Exposure of wildlife to Active Pharmaceutical Ingredients (APIs) is likely to occur but studies of risk are limited. One exposure pathway that has received attention is trophic transfer of APIs in a water-fish-osprey food chain. Samples of water, fish plasma and osprey plasma were collected from Delaware River and Bay, and analyzed for 21 APIs. Only 2 of 21 analytes exceeded method detection limits in osprey plasma (acetaminophen and diclofenac) with plasma levels typically 2–3 orders of magnitude below human therapeutic concentrations (HTC). We built upon a screening level model used to predict osprey exposure to APIs in Chesapeake Bay and evaluated whether exposure levels could have been predicted in Delaware Bay had we just measured concentrations in water or fish. Use of surface water and BCFs did not predict API concentrations in fish well, likely due to fish movement patterns, and partitioning and bioaccumulation uncertainties associated with these ionizable chemicals. Input of highest measured API concentration in fish plasma combined with pharmacokinetic data accurately predicted that diclofenac and acetaminophen would be the APIs most likely detected in osprey plasma. For the majority of APIs modeled, levels were not predicted to exceed 1 ng/mL or method detection limits in osprey plasma. Based on the target analytes examined, there is little evidence that APIs represent a significant risk to ospreys nesting in Delaware Bay. If an API is present in fish orders of magnitude below HTC, sampling of fish-eating birds is unlikely to be necessary. However, several human pharmaceuticals accumulated in fish plasma within a recommended safety factor for HTC. It is now important to expand the scope of diet-based API exposure modeling to include alternative exposure pathways (e.g., uptake from landfills, dumps and wastewater treatment plants) and geographic locations (developing countries) where API contamination of the environment may represent greater risk.

Don't Look Now - Tiltrotors Are Coming!

NASA Technical Reports Server (NTRS)

Dugan, Daniel C.; Hindson, William S. (Technical Monitor)

1997-01-01

This paper traces the history of tiltrotors, beginning with the XV-3 and XV-15, to the Marine's V-22 Osprey. The design of the first civil tiltrotor, the Bell-Boeing 609, is now complete and the revolutionary aircraft will debut in 2001 after completion of a rigorous test program. The XV-3 proved the safety and ease of transition from the helicopter mode to the airplane mode; however, it had aeroelastic stability and performance problems. The XV-15 was the tiltrotor of the late 70s and the 80s. In 1981, it was demonstrated to the international aviation community at the Paris Air Show. Its success led to the development of the V-22 Osprey and it returned to Paris in 1995 in the livery of a civil tiltrotor. There, it flew joint demonstrations with the Osprey. One is still flying today as a Civil Tiltrotor (CTR) demonstrator. The V-22 first flew in Mar 1989. After a stormy procurement cycle, the Full Scale Development (FSD) aircraft were superseded by the improved Engineering and Manufacturing Development (EMD) aircraft. The #7 Osprey made its first flight eight years later. Many highlights of the FSD and EMD flight test programs will be covered and illustrated with video clips. The Bell-Boeing 609 design was unveiled at the Smithsonian in November, 1996 and the first orders have been taken for this 250 knot, corporate size tiltrotor. Flight testing of this innovative aircraft will commence in 1999.

Environmental pollutant and necropsy data for ospreys from the eastern United States, 1975-1982

USGS Publications Warehouse

Wiemeyer, Stanley N.; Schmeling, Shelia K.; Anderson, Allen

1987-01-01

Twenty-three ospreys (Pandion haliaetus) found dead or moribund in the eastern United States during 1975–1982 were necropsied and selected tissues were analyzed for organo-chlorines and metals. Major causes or factors contributing to death were trauma, impact injuries, and emaciation. DDE was detected in 96% of the osprey carcasses, DDD in 65%, DDT and heptachlor epoxide in 13%, dieldrin, oxychlordane, and cis-nonachlor in 35%, cis-chlordane in 52%, trans-nonachlor in 45%, and PCB's in 83%. Carcasses of immature ospreys from the Chesapeake Bay had significantly lower concentrations of DDE, DDD + DDT, cis-chlordane, and PCB's than carcasses of adults from the same area. Concentrations of some organochlorines in ospreys from the Chesapeake Bay declined significantly from 1971–1973 to 1975–1982. Significant differences in concentrations of certain metals in the ospreys' livers were noted between time periods, and sex and age groups for birds from the Chesapeake Bay. During 1975–1982, adults had significantly lower concentrations of chromium, copper, and arsenic than immatures and nestlings, and adult males had higher mercury concentrations than adult females. Adult females had lower zinc concentrations in 1975–1982 than in 1971–1973. Immatures and nestlings had higher concentrations of chromium and lead in 1975–1982 than in 1971–1973. A slightly elevated concentration of chromium (1.7 ppm) or arsenic (3.2 ppm) was found in the livers of individual ospreys. Several ospreys had elevated concentrations of mercury in their livers; two ospreys had more than 20 ppm which may have contributed to their deaths.

Exposure and food web transfer of pharmaceuticals in ospreys (Pandion haliaetus): Predictive model and empirical data

USGS Publications Warehouse

Lazarus, Rebecca S.; Rattner, Barnett A.; Du, Bowen; McGowan, Peter C.; Blazer, Vicki S.; Ottinger, Mary Ann

2015-01-01

The osprey (Pandion haliaetus) is a well-known sentinel of environmental contamination, yet no studies have traced pharmaceuticals through the water–fish–osprey food web. A screening-level exposure assessment was used to evaluate the bioaccumulation potential of 113 pharmaceuticals and metabolites, and an artificial sweetener in this food web. Hypothetical concentrations in water reflecting “wastewater effluent dominated” or “dilution dominated” scenarios were combined with pH-specific bioconcentration factors (BCFs) to predict uptake in fish. Residues in fish and osprey food intake rate were used to calculate the daily intake (DI) of compounds by an adult female osprey. Fourteen pharmaceuticals and a drug metabolite with a BCF greater than 100 and a DI greater than 20 µg/kg were identified as being most likely to exceed the adult human therapeutic dose (HTD). These 15 compounds were also evaluated in a 40 day cumulative dose exposure scenario using first-order kinetics to account for uptake and elimination. Assuming comparable absorption to humans, the half-lives (t1/2) for an adult osprey to reach the HTD within 40 days were calculated. For 3 of these pharmaceuticals, the estimated t1/2 in ospreys was less than that for humans, and thus an osprey might theoretically reach or exceed the HTD in 3 to 7 days. To complement the exposure model, 24 compounds were quantified in water, fish plasma, and osprey nestling plasma from 7 potentially impaired locations in Chesapeake Bay. Of the 18 analytes detected in water, 8 were found in fish plasma, but only 1 in osprey plasma (the antihypertensive diltiazem). Compared to diltiazem detection rate and concentrations in water (10/12 detects, osprey

cOSPREY: A Cloud-Based Distributed Algorithm for Large-Scale Computational Protein Design

PubMed Central

Pan, Yuchao; Dong, Yuxi; Zhou, Jingtian; Hallen, Mark; Donald, Bruce R.; Xu, Wei

2016-01-01

Abstract Finding the global minimum energy conformation (GMEC) of a huge combinatorial search space is the key challenge in computational protein design (CPD) problems. Traditional algorithms lack a scalable and efficient distributed design scheme, preventing researchers from taking full advantage of current cloud infrastructures. We design cloud OSPREY (cOSPREY), an extension to a widely used protein design software OSPREY, to allow the original design framework to scale to the commercial cloud infrastructures. We propose several novel designs to integrate both algorithm and system optimizations, such as GMEC-specific pruning, state search partitioning, asynchronous algorithm state sharing, and fault tolerance. We evaluate cOSPREY on three different cloud platforms using different technologies and show that it can solve a number of large-scale protein design problems that have not been possible with previous approaches. PMID:27154509

Fall migration routes, timing, and wintering sites of North American ospreys as determined by satellite telemetry

USGS Publications Warehouse

Martell, M.S.; Henny, Charles J.; Nye, P.; Solensky, Matthew J.

2001-01-01

Satellite telemetry was used to determine fall migratory movements of Ospreys (Pandion haliaetus) breeding in the United States. Study areas were established along the lower Columbia River between Oregon and Washington; in north-central Minnesota; on Shelter Island, New York; and in southern New Jersey. Seventy-four adults (25 males, 49 females) were tracked from 1995 through 1999. Migration routes differed among populations but not by sex. Western Ospreys migrated through California and to a lesser degree other western states and wintered in Mexico (88%), El Salvador (6%), and Honduras (6%) (25.9A?N to 13.0A?N and 108.3A?W to 87.3A?W). Minnesota Ospreys migrated along three routes: (1) through the Central U.S. and then along the east coast of Mexico, (2) along the Mississippi River Valley, then across the Gulf of Mexico, or (3) through the southeastern U.S., then across the Caribbean. East Coast birds migrated along the eastern seaboard of the U.S., through Florida, and across the Caribbean. Midwestern birds wintered from Mexico south to Bolivia (22.35A?N to 13.64A?S, and 91.75A?W to 61.76A?W), while East Coast birds wintered from Florida to as far south as Brazil (27.48A?N to 18.5A?S and 80.4A?W to 57.29A?W). Dates of departure from breeding areas differed significantly between sexes and geographic regions, with females leaving earlier than males. Western birds traveled a shorter distance than either midwestern or eastern Ospreys. Females traveled farther than males from the same population, which resulted in females typically wintering south of males.

V-22 Osprey Tilt-Rotor Aircraft: Background and Issues for Congress

DTIC Science & Technology

2009-12-22

perpendicular to spindle shaft ) by not producing the commands requested by the pilot’s controls positions. This tends to significantly reduce the severity of... designed to transport 24 fully equipped Marines at a cruising speed of about 250 knots (about 288 mph), exceeding the performance of the Marine Corps CH...Background and Issues for Congress Congressional Research Service 2 22 is designed to carry 18 troops, with auxiliary fuel tanks increasing the

V-22 Osprey Tilt-Rotor Aircraft

DTIC Science & Technology

2007-03-13

destroying the aircraft. This accident was caused by a fire resulting from hydraulic component failures and design problems in the engine nacelles.3 Flight...the Marine Corps reported that the crash was caused by a burst hydraulic line in one of the Osprey’s two engine casings, and a software malfunction...that caused the aircraft to accelerate and decelerate unpredictably and violently when the pilots tried to compensate for the hydraulic CRS-6 7 An un

V-22 Osprey Tilt-Rotor Aircraft

DTIC Science & Technology

2009-01-02

Station, VA, killing seven people and destroying the aircraft. This accident was caused by a fire resulting from hydraulic component failures and...April 5, 2001, the Marine Corps reported that the crash was caused by a burst hydraulic line in one of the Osprey’s two engine casings, and a software...malfunction that caused the aircraft to accelerate and decelerate unpredictably and violently when the pilots tried to compensate for the hydraulic

V-22 Osprey Guidebook 2011/2012

DTIC Science & Technology

2012-01-01

and new missions to be accomplished that were previously unachievable on legacy platforms. Comprehensively tested and in full rate production, the...The government-industry team is executing a coordinated strategy to solve these issues which is spiral in nature and is providing incremental...Model . . . . . . . . . . . .AE1107C (Rolls-Royce Liberty) AEO VTOL normal power, shp (kW

Distribution and abundance of nesting ospreys in the United States

USGS Publications Warehouse

Henny, C.J.

1983-01-01

Nesting Ospreys (Pandion haliaetus) in the contiguous United States now number about 8,000 pairs. Five regional populations exist (in order of abundance): Atlantic Coast, Florida and Gulf Coast, Pacific Northwest, Western Interior, and Great Lakes. Pesticides severely impacted the populations in the northern portion of the Atlantic Coast (Boston to Cape May) and the Great Lakes, but both are now recovering. During recent years in the west, especially in the Western Interior, reservoirs have been responsible for a range expansion and, perhaps, a population increase. However, a strong fidelity to ancestral breeding areas (short dispersal distance) has slowed the range expansion. Unique introductions to distant reservoirs (from breeding populations) are now being made and followed with intense interest. Ospreys adapted to man, his structures, and many of his habitat changes, but proved sensitive to his chemical pollutants. These characteristics make the Osprey an excellent environmental indicator species.

Satellite telemetry and prey sampling reveal contaminant sources to Pacific Northwest Ospreys.

PubMed

Elliott, John E; Morrissey, Christy A; Henny, Charles J; Inzunza, Ernesto Ruelas; Shaw, Patrick

2007-06-01

Migratory behavior can be an important factor in determining contaminant exposure in avian populations. Accumulation of organochlorine (OC) pesticides while birds are wintering in tropical regions has been cited often as the reason for high concentrations in migrant populations. To explore this issue, we satellite tracked 16 Ospreys (Pandion haliaetus) over the period 1996-2003 from breeding sites in British Columbia, Canada, and integrated the results into a database on 15 Ospreys that were satellite tracked over the period 1995-1999, from breeding locations in Washington and Oregon, USA. Data on wintering sites of 31 Ospreys in Mexico and Central America were used for spatially targeted sampling of prey fish. Concentrations of the main organochlorine contaminant, p,p'-dichloro-diphenyl-dichloroethylene (DDE), in fish composites from Mexico ranged from 0.005 to 0.115 nicrog/g wet mass. Significant differences existed among fish families in p,p'-DDE, total dichloro-diphenyl-trichloroethane (sigmaDDT), sigmachlordanes, and total polychlorinated biphenyls (sigmaPCBs). Catfish (family Ariidae) generally had significantly higher levels of DDT metabolites and other organochlorine contaminants compared to other fish families collected. Differences in prey contaminant levels were detected among the collection sites around coastal Mexico, with fish from Veracruz State generally having higher levels of DDT metabolites, sigmachlordanes, sigmaPCBs, and hexachlorobenzene. Eggs collected from 16 nests throughout the Pacific Northwest (nine from British Columbia, seven from Oregon and Washington) where Ospreys had been satellite tagged, showed marked variation in levels of DDT metabolites (p,p'-DDE; range 0.02-10.14 microg/g). Wintering site had no significant effect on contaminant concentrations in sample eggs from those specific Ospreys; rather concentrations of p,p'-DDE, were predicted by breeding sites with highest levels in eggs of Ospreys breeding in the lower Columbia

Helminth parasites of the osprey, Pandion haliaetus, in North America

USGS Publications Warehouse

Kinsella, J.M.; Cole, Rebecca A.; Forrester, Donald J.; Roderick, Constance L.

1996-01-01

A total of 28 species of helminths (17 trematodes, 3 cestodes, 7 nematodes, and 1 acanthocephalan) was recovered from 17 ospreys (Pandion haliaetus) from the United States. Intensities of infection were low and no lesions were attributed to the parasites. Seven species appear to be specialists in ospreys, 2 species generalists in raptors, and the remainder generalists in other orders of fish-eating birds. Pandiontrema rjikovi, Diasiella diasi, and Contracaecum pandioni are reported for the first time from North America.

Prey of nesting ospreys on the Willamette and Columbia Rivers, Oregon and Washington

USGS Publications Warehouse

Johnson, B.L.; Kaiser, J.L.; Henny, C.J.; Grove, R.A.

2008-01-01

To more effectively use ospreys as a biomonitoring tool and to better assess contaminant pathways, the diet of nesting ospreys (Pandion haliaetus) was studied along the lower Columbia and upper mainstem Willamette rivers by evaluating prey remains collected from wire baskets constructed under artificial feeding perches installed near nest sites and from the ground beneath natural feeding perches and nests. Prey remains from 1997-2004 on the Columbia River and 1993 (previously published) and 2001 on the Willamette River were evaluated and compared. Largescale suckers (Catostomus macrocheilus) were the predominate fish species identified in collections from the Columbia River (61.5% [84.3% biomass]) and Willamette River (76.0% [92.7% biomass]). Prey fish diversity, when based only on ground collections, was higher in the Columbia (2.45) than the Willamette river (1.92) (P = 0.038). Prey fish diversity in collections from the Willamette River did not differ between this study (2001) and previous study (1993) (P = 0.62). Fishbones recovered in wire baskets are likely more representative of osprey diet compared to bones recovered from the ground, because prey diversity was higher among basket samples compared to ground collections (wire basket diversity = 5.25 vs. ground collection diversity = 2.45, P = 0.011). Soft-boned salmonids (Oncorhynchus spp.), American shad (Alosa sapidissima), and mountain whitefish (Prosopium williamsoni) were probably underrepresented in collections obtained from the ground. Study results suggest that baskets provide a better method for assessing osprey diet than other indirect methods. These findings augment available osprey food-habits information and provide additional biological and ecological information to better assess potential impacts of various environmental contaminants on nesting ospreys.

Juvenile Osprey Navigation during Trans-Oceanic Migration

PubMed Central

Horton, Travis W.; Bierregaard, Richard O.; Zawar-Reza, Peyman; Holdaway, Richard N.; Sagar, Paul

2014-01-01

To compensate for drift, an animal migrating through air or sea must be able to navigate. Although some species of bird, fish, insect, mammal, and reptile are capable of drift compensation, our understanding of the spatial reference frame, and associated coordinate space, in which these navigational behaviors occur remains limited. Using high resolution satellite-monitored GPS track data, we show that juvenile ospreys (Pandion haliaetus) are capable of non-stop constant course movements over open ocean spanning distances in excess of 1500 km despite the perturbing effects of winds and the lack of obvious landmarks. These results are best explained by extreme navigational precision in an exogenous spatio-temporal reference frame, such as positional orientation relative to Earth's magnetic field and pacing relative to an exogenous mechanism of keeping time. Given the age (<1 year-old) of these birds and knowledge of their hatching site locations, we were able to transform Enhanced Magnetic Model coordinate locations such that the origin of the magnetic coordinate space corresponded with each bird's nest. Our analyses show that trans-oceanic juvenile osprey movements are consistent with bicoordinate positional orientation in transformed magnetic coordinate or geographic space. Through integration of movement and meteorological data, we propose a new theoretical framework, chord and clock navigation, capable of explaining the precise spatial orientation and temporal pacing performed by juvenile ospreys during their long-distance migrations over open ocean. PMID:25493430

Satellite-tagged osprey nearly sets longevity record and productivity response to initial captures

USGS Publications Warehouse

Henny, Charles J.; Martell, Mark S.

2017-01-01

We equipped adult Ospreys (Pandion haliaetus) from 24 nests in Oregon/Washington with satellite-tracked battery-powered radios, known as platform transmitter terminals (PTTs), in 1996–1999. These Ospreys from the lower Columbia River (river miles 76–286), and the Willamette Valley in western Oregon were part of a larger study of Osprey fall migration, wintering ecology, and spring migration, which included additional adults from the Upper Midwest and East Coast of the United States (Martell et al. 2001, 2014, Washburn et al. 2014). These early-generation PTTs weighed 30–35 g (Microwave Telemetry Inc., Columbia, MD U.S.A.) and utilized the ARGOS tracking system (www.argos-system.org). We placed PTTs on the birds' backs using Teflon ribbon (Bally Ribbon, Bally, PA U.S.A.) in a standard backpack configuration (Kenward 2001). With the mass of adult male Ospreys 1400 to 1500 g (Poole et al. 2002), the ratio of tag mass to body mass was 2.0 to 2.5%. Ospreys also received a standard size 8 bird band (U.S. Geological Survey) on one leg and a numbered color band on the other. For more details on trapping techniques, attachment procedures, the battery-powered units, turn-on, turn-off cycles, and tracking equipment, see Martell et al. (2001).

Satellite telemetry and prey sampling reveal contaminant sources to pacific northwest ospreys

USGS Publications Warehouse

Elliott, J.E.; Morrissey, C.A.; Henny, C.J.; Inzunza, E.R.; Shaw, P.

2007-01-01

Migratory behavior can be an important factor in determining contaminant exposure in avian populations. Accumulation of organochlorine (OC) pesticides while birds are wintering in tropical regions has been cited often as the reason for high concentrations in migrant populations. To explore this issue, we satellite tracked 16 Ospreys (Pandion haliaetus) over the period 1996-2003 from breeding sites in British Columbia, Canada, and integrated the results into a database on 15 Ospreys that were satellite tracked over the period 1995-1999, from breeding locations in Washington and Oregon, USA. Data on wintering sites of 31 Ospreys in Mexico and Central America were used for spatially targeted sampling of prey fish. Concentrations of the main organochlorine contaminant, p,p???-dichloro-diphenyl-dichloroethylene (DDE), in fish composites from Mexico ranged from 0.005 to 0.115 ??g/g wet mass. Significant differences existed among fish families in p,p???-DDE, total dichloro- diphenyltrichloroethane (??DDT), ??chlordanes, and total polychlorinated biphenyls (??PCBs). Catfish (family Ariidae) generally had significantly higher levels of DDT metabolites and other organochlorine contaminants compared to other fish families collected. Differences in prey contaminant levels were detected among the collection sites around coastal Mexico, with fish from Veracruz State generally having higher levels of DDT metabolites, ??chlordanes, ??PCBs, and hexachlorobenzene. Eggs collected from 16 nests throughout the Pacific Northwest (nine from British Columbia, seven from Oregon and Washington) where Ospreys had been satellite tagged, showed marked variation in levels of DDT metabolites (p,p???-DDE; range 0.02-10.14 ??g/g). Wintering site had no significant effect on contaminant concentrations in sample eggs from those specific Ospreys; rather concentrations of p,p???-DDE, were predicted by breeding sites with highest levels in eggs of Ospreys breeding in the lower Columbia River

North American osprey populations and contaminants: Historic and contemporary perspectives

USGS Publications Warehouse

Henny, Charles J.; Grove, Robert A.; Kaiser, James L.; Johnson, Branden L.

2010-01-01

Osprey (Pandion haliaetus) populations were adversely affected by DDT and perhaps other contaminants in the United States and elsewhere. Reduced productivity, eggshell thinning, and high DDE concentrations in eggs were the signs associated with declining osprey populations in the 1950s, 1960s, and 1970s. The species was one of the first studied on a large scale to bring contaminant issues into focus. Although few quantitative population data were available prior to the 1960s, many osprey populations in North America were studied during the 1960s and 1970s with much learned about basic life history and biology. This article reviews the historical and current effects of contaminants on regional osprey populations. Breeding populations in many regions of North America showed post-DDT-era (1972) population increases of varying magnitudes, with many populations now appearing to stabilize at much higher numbers than initially reported in the 1970s and 1980s. However, the magnitude of regional population increases in the United States between 1981 (first Nationwide Survey, ∼8,000 pairs), when some recovery had already occurred, 1994 (second survey, ∼14,200), and 2001 (third survey, ∼16,000–19,000), or any other years, is likely not a simple response to the release from earlier contaminant effects, but a response to multi-factorial effects. This indirect “contaminant effects” measurement comparing changes (i.e., recovery) in post-DDT-era population numbers over time is probably confounded by changing human attitudes toward birds of prey (shooting, destroying nests, etc.), changing habitats, changing fish populations, and perhaps competition from other species. The species' adaptation to newly created reservoirs and its increasing use of artificial nesting structures (power poles, nesting platforms, cell towers, channel markers, offshore duck blinds, etc.) are two important factors. The timing of the initial use of artificial nesting structures, which replaced

Chesapeake Bay fish–osprey (Pandion haliaetus) food chain: Evaluation of contaminant exposure and genetic damage

USGS Publications Warehouse

Lazarus, Rebecca S.; Rattner, Barnett A.; McGowan, Peter C.; Hale, Robert C.; Karouna-Reiner, Natalie K.; Erickson, Richard A.; Ottinger, Mary Ann

2016-01-01

From 2011 to 2013, a large-scale ecotoxicological study was conducted in several Chesapeake Bay (USA) tributaries (Susquehanna River and flats, the Back, Baltimore Harbor/Patapsco Rivers, Anacostia/ middle Potomac, Elizabeth and James Rivers) and Poplar Island as a mid-Bay reference site. Osprey (Pandion haliaetus) diet and the transfer of contaminants from fish to osprey eggs were evaluated. The most bioaccumulative compounds (biomagnification factor > 5) included p,p′-dichlorodiphenyldichloroethylene (DDE), total polychlorinated biphenyls (PCBs), total polybrominated diphenyl ethers (PBDEs), and bromodiphenyl ether (BDE) congeners 47, 99, 100, and 154. This analysis suggested that alternative brominated flame retardants and other compounds (methoxytriclosan) are not appreciably biomagnifying. A multivariate analysis of similarity indicated that major differences in patterns among study sites were driven by PCB congeners 105, 128, 156, 170/190, and 189, and PBDE congeners 99 and 209. An integrative redundancy analysis showed that osprey eggs from Baltimore Harbor/Patapsco River and the Elizabeth River had high residues of PCBs and p,p′-DDE, with PBDEs making a substantial contribution to overall halogenated contamination on the Susquehanna and Anacostia/middle Potomac Rivers. The redundancy analysis also suggested a potential relation between PBDE residues in osprey eggs and oxidative DNA damage in nestling blood samples. The results also indicate that there is no longer a discernible relation between halogenated contaminants in osprey eggs and their reproductive success in Chesapeake Bay. Osprey populations are thriving in much of the Chesapeake, with productivity rates exceeding those required to sustain a stable population.

KENIS: a high-performance thermal imager developed using the OSPREY IR detector

NASA Astrophysics Data System (ADS)

Goss, Tristan M.; Baker, Ian M.

2000-07-01

`KENIS', a complete, high performance, compact and lightweight thermal imager, is built around the `OSPREY' infrared detector from BAE systems Infrared Ltd. The `OSPREY' detector uses a 384 X 288 element CMT array with a 20 micrometers pixel size and cooled to 120 K. The relatively small pixel size results in very compact cryogenics and optics, and the relatively high operating temperature provides fast start-up time, low power consumption and long operating life. Requiring single input supply voltage and consuming less than 30 watts of power, the thermal imager generates both analogue and digital format outputs. The `KENIS' lens assembly features a near diffraction limited dual field-of-view optical system that has been designed to be athermalized and switches between fields in less than one second. The `OSPREY' detector produces near background limited performance with few defects and has special, pixel level circuitry to eliminate crosstalk and blooming effects. This, together with signal processing based on an effective two-point fixed pattern noise correction algorithm, results in high quality imagery and a thermal imager that is suitable for most traditional thermal imaging applications. This paper describes the rationale used in the development of the `KENIS' thermal imager, and highlights the potential performance benefits to the user's system, primarily gained by selecting the `OSPREY' infra-red detector within the core of the thermal imager.

Biomagnification factors (fish to Osprey eggs from Willamette River, Oregon, U.S.A.) for PCDDs, PCDFs, PCBs and OC pesticides.

PubMed

Henny, Charles J; Kaiser, James L; Grove, Robert A; Bentley, V Raymond; Elliott, John E

2003-06-01

A migratory population of 78 pairs of Osprey (Pandion haliaetus) nesting along the Willamette River in western Oregon was studied in 1993. The study was designed to determine contaminant concentrations in eggs, contaminant concentrations in fish species predominant in the Ospreys diet, and Biomagnification Factors (BMFs) of contaminants from fish species eaten to Osprey eggs. Ten Osprey eggs and 25 composite samples of fish (3 species) were used to evaluate organochlorine (OC) pesticides, polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs). Mercury was also analyzed in fish. Geometric mean residues in Osprey eggs were judged low, e.g., DDE 2.3 microg g(-1) wet weight (ww), sigma PCBs 0.69 microg g(-1), 2,3,7,8-TCDD 2.3 ng kg(-1), and generally well below known threshold values for adverse effects on productivity, and the population was increasing. Osprey egg residue data presented by River Mile (RM) are discussed, e.g., higher PCDDs were generally found immediately downstream of paper mills and eggs from the Willamette River had significantly elevated PCBs and PCDDs compared to reference eggs collected nearby in the Cascade Mountains. Prey remains at nest sites indicated that the Largescale Sucker (Catostomus macrocheilus) and Northern Pikeminnow (Ptychocheilus oregonensis) accounted for an estimated 90.1% of the biomass in the Osprey diet, and composite samples of these two species were collected from different sampling sites throughout the study area for contaminant analyses. With the large percentage of the fish biomass in the Osprey diet sampled for contaminants (and fish eaten by Ospreys similar in size to those chemically analyzed), and fish contaminant concentrations weighted by biomass intake, a mean BMF was estimated from fish to Osprey eggs for the large series of contaminants. BMFs ranged from no biomagnification (0.42) for 2,3,7,8-TCDF to 174 for OCDD. Our findings for the migratory

Biomagnification factors (fish to osprey eggs from Willamette River, Oregon, U.S.A.) for PCDDS, PCDFS, PCBS, and OC pesticides

USGS Publications Warehouse

Henny, Charles J.; Kaiser, James L.; Grove, Robert A.; Bentley, V.R.; Elliot, J.E.

2003-01-01

A migratory population of 78 pairs of Osprey (Pandion haliaetus) nesting along the Willamette River in westernOregon was studied in 1993. The study was designed to determinecontaminant concentrations in eggs, contaminant concentrationsin fish species predominant in the Ospreys diet, andBiomagnification Factors (BMFs) of contaminants from fish specieseaten to Osprey eggs. Ten Osprey eggs and 25 composite samplesof fish (3 species) were used to evaluate organochlorine (OC)pesticides, polychlorinated biphenyls (PCBs), polychlorinateddibenzo-p-dioxins (PCDDs), and polychlorinated dibenzofurans(PCDFs). Mercury was also analyzed in fish. Geometric meanresidues in Osprey eggs were judged low, e.g., DDE 2.3 g g-1 wet weight (ww), PCBs 0.69 g g-1, 2,3,7,8-TCDD 2.3 ng kg-1, and generally well below known threshold values for adverse effects on productivity, and the population was increasing. Osprey egg residue data presentedby River Mile (RM) are discussed, e.g., higher PCDDs were generally found immediately downstream of paper mills and eggsfrom the Willamette River had significantly elevated PCBs and PCDDs compared to reference eggs collected nearby in the CascadeMountains. Prey remains at nest sites indicated that the Largescale Sucker (Catostomus macrocheilus) and NorthernPikeminnow (Ptychocheilus oregonensis) accounted for an estimated 90.1% of the biomass in the Osprey diet, and composite samples of these two species were collected from different sampling sites throughout the study area for contaminant analyses. With the large percentage of the fishbiomass in the Osprey diet sampled for contaminants (and fisheaten by Ospreys similar in size to those chemically analyzed),and fish contaminant concentrations weighted by biomass intake, a mean BMF was estimated from fish to Osprey eggs for the largeseries of contaminants. BMFs ranged from no biomagnification(0.42) for 2,3,7,8-TCDF to 174 for OCDD. Our findings for themigratory Osprey were compared to BMFs for the resident

Doppler Lidar Observations of an Atmospheric Thermal Providing Lift to Soaring Ospreys

NASA Technical Reports Server (NTRS)

Koch, Grady J.

2005-01-01

Vertical wind measurements are presented of an atmospheric thermal in which ospreys (Pandion haliaetus) were soaring. These observations were made with a Doppler lidar, allowing high spatial and high temporal resolution wind profiles in clear air. The thermal was generated at the onset of a cloud bank, producing a rolling eddy upon which ospreys were seen to be riding. A determination is made on the size and shape of the thermal, wind speeds involved, and the altitude to which the birds could have ridden the thermal.

Migration strategies and wintering areas of North American ospreys as revealed by satellite telemetry

USGS Publications Warehouse

Martell, Mark S.; Henny, Charles J.; Nye, P.; Solensky, Matthew J.

2000-01-01

Since 1995 we have trapped and tagged 110 Ospreys (Pandion haliaetus) from 12 study sites in 8 states (Fig. 1). This total includes 71 females, 32 males and 7 juveniles. Our study areas encompass the major Osprey population concentrations found in the United States including the Western States, the Great Lakes region and the Eastern Seaboard.Tagging of nesting pairs along with three complete family groups revealed that departure times from nesting areas varied by gender; with females leaving before the juveniles and themales departing last. Neither nesting pairs, nor families, migrated or wintered together (Fig. 2). Departure dates from the breeding areas ranged from 12 July to 1 October. Migration routes differed between populations but not gender (Fig. 3). Western Ospreys migrated through California and to a lesser degree other western states and then into Mexico. MinnesotaOspreys migrated along three routes; 1) through the central U.S. and then along the east coast of Mexico, 2) along the Mississippi River then across the Gulf of Mexico, or 3) through the Southeastern U.S., then across the Caribbean. East Coast birds migrated along the Eastern Seaboard of the U.S. through Florida and across the Caribbean.

Multi-component testing using HZ-PAN and AgZ-PAN Sorbents for OSPREY Model validation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garn, Troy G.; Greenhalgh, Mitchell; Lyon, Kevin L.

2015-04-01

In efforts to further develop the capability of the Off-gas SeParation and RecoverY (OSPREY) model, multi-component tests were completed using both HZ-PAN and AgZ-PAN sorbents. The primary purpose of this effort was to obtain multi-component xenon and krypton capacities for comparison to future OSPREY predicted multi-component capacities using previously acquired Langmuir equilibrium parameters determined from single component isotherms. Experimental capacities were determined for each sorbent using two feed gas compositions of 1000 ppmv xenon and 150 ppmv krypton in either a helium or air balance. Test temperatures were consistently held at 220 K and the gas flowrate was 50 sccm.more » Capacities were calculated from breakthrough curves using TableCurve® 2D software by Jandel Scientific. The HZ-PAN sorbent was tested in the custom designed cryostat while the AgZ-PAN was tested in a newly installed cooling apparatus. Previous modeling validation efforts indicated the OSPREY model can be used to effectively predict single component xenon and krypton capacities for both engineered form sorbents. Results indicated good agreement with the experimental and predicted capacity values for both krypton and xenon on the sorbents. Overall, the model predicted slightly elevated capacities for both gases which can be partially attributed to the estimation of the parameters and the uncertainty associated with the experimental measurements. Currently, OSPREY is configured such that one species adsorbs and one does not (i.e. krypton in helium). Modification of OSPREY code is currently being performed to incorporate multiple adsorbing species and non-ideal interactions of gas phase species with the sorbent and adsorbed phases. Once these modifications are complete, the sorbent capacities determined in the present work will be used to validate OSPREY multicomponent adsorption predictions.« less

Assessment of Contaminant Exposure and Effects on Ospreys Nesting along the Lower Duwamish River, Washington, 2006-07

USGS Publications Warehouse

Johnson, Branden L.; Henny, Charles J.; Kaiser, James L.; Davis, Jay W.; Schulz, Edmund P.

2009-01-01

We evaluated the effects of contaminants on osprey (Pandion haliaetus) nesting along the lower Duwamish River (LDR), Washington, and used the upper reach of the Willamette River (WR), Oregon, as a reference site. Osprey eggs and nestling blood (plasma) were collected at nests along the LDR (11 eggs, 7 plasmas) and WR (10 eggs, 6 plasmas) in 2006-07 and analyzed for contaminants. Additionally, hematology and serum chemistries were determined in the blood/plasma samples of nestlings (about 35-45 days old) and were used as potential indicators of stress induced by contaminant exposure. Detailed foraging information for ospreys nesting along the LDR was collected and evaluated to better understand contaminant profiles observed in the eggs and plasma. Additional residue data from 26 osprey eggs collected and analyzed in 2002-03 from nests along the LDR, Snohomish River Estuary (SRE) and Lake Washington (LW) in the Puget Sound (PS) region also were evaluated.

Wastewater dilution index partially explains observed polybrominated diphenyl ether flame retardant concentrations in osprey eggs from Columbia River Basin, 2008-2009

USGS Publications Warehouse

Henry, Charles J.; Grove, Robert A.; Kaiser, James L.; Johnson, Branden L.; Furl, Chad V.; Letcher, Robert J.

2011-01-01

Several polybrominated biphenyl ether (PBDE) congeners were found in all 175 osprey (Pandion haliaetus) eggs collected from the Columbia River Basin between 2002 and 2009. ΣPBDE concentrations in 2008–2009 were highest in osprey eggs from the two lowest flow rivers studied; however, each river flowed through relatively large and populous metropolitan areas (Boise, Idaho and Spokane, Washington). We used the volume of Wastewater Treatment Plant (WWTP) discharge, a known source of PBDEs, as a measure of human activity at a location, and combined with river flow (both converted to millions of gallons/day) created a novel approach (an approximate Dilution Index) to relate waterborne contaminants to levels of these contaminants that reach avian eggs. This approach provided a useful understanding of the spatial osprey egg concentration patterns observed. Individual osprey egg concentrations along the Upper Willamette River co-varied with the Dilution Index, while combined egg data (geometric means) from rivers or segments of rivers showed a strong, significant relationship to the Dilution Index with one exception, the Boise River. There, we believe osprey egg concentrations were lower than expected because Boise River ospreys foraged perhaps 50–75% of the time off the river at ponds and lakes stocked with fish that contained relatively low ΣPBDE concentrations. Our limited temporal data at specific localities (2004–2009) suggests that ΣPBDE concentrations in osprey eggs peaked between 2005 and 2007, and then decreased, perhaps in response to penta- and octa-PBDE technical mixtures no longer being used in the USA after 2004. Empirical estimates of biomagnification factors (BMFs) from fish to osprey eggs were 3.76–7.52 on a wet weight (ww) basis or 4.37–11.0 lipid weight. Our earlier osprey study suggested that ΣPBDE egg concentrations >1,000 ng/g ww may reduce osprey reproductive success. Only two of the study areas sampled in 2008–2009 contained

Chesapeake Bay fish-osprey (Pandion haliaetus) food chain: Evaluation of contaminant exposure and genetic damage.

PubMed

Lazarus, Rebecca S; Rattner, Barnett A; McGowan, Peter C; Hale, Robert C; Karouna-Renier, Natalie K; Erickson, Richard A; Ottinger, Mary Ann

2016-06-01

From 2011 to 2013, a large-scale ecotoxicological study was conducted in several Chesapeake Bay (USA) tributaries (Susquehanna River and flats, the Back, Baltimore Harbor/Patapsco Rivers, Anacostia/ middle Potomac, Elizabeth and James Rivers) and Poplar Island as a mid-Bay reference site. Osprey (Pandion haliaetus) diet and the transfer of contaminants from fish to osprey eggs were evaluated. The most bioaccumulative compounds (biomagnification factor > 5) included p,p'-dichlorodiphenyldichloroethylene (DDE), total polychlorinated biphenyls (PCBs), total polybrominated diphenyl ethers (PBDEs), and bromodiphenyl ether (BDE) congeners 47, 99, 100, and 154. This analysis suggested that alternative brominated flame retardants and other compounds (methoxytriclosan) are not appreciably biomagnifying. A multivariate analysis of similarity indicated that major differences in patterns among study sites were driven by PCB congeners 105, 128, 156, 170/190, and 189, and PBDE congeners 99 and 209. An integrative redundancy analysis showed that osprey eggs from Baltimore Harbor/Patapsco River and the Elizabeth River had high residues of PCBs and p,p'-DDE, with PBDEs making a substantial contribution to overall halogenated contamination on the Susquehanna and Anacostia/middle Potomac Rivers. The redundancy analysis also suggested a potential relation between PBDE residues in osprey eggs and oxidative DNA damage in nestling blood samples. The results also indicate that there is no longer a discernible relation between halogenated contaminants in osprey eggs and their reproductive success in Chesapeake Bay. Osprey populations are thriving in much of the Chesapeake, with productivity rates exceeding those required to sustain a stable population. Environ Toxicol Chem 2016;35:1560-1575. Published 2016 Wiley Periodicals Inc. on behalf of SETAC. This article is a US Government work and, as such, is in the public domain in the United States of America. Published 2016 Wiley

Osprey: worldwide sentinel species for assessing and monitoring environmental contamination in rivers, lakes, reservoirs, and estuaries.

PubMed

Grove, Robert A; Henny, Charles J; Kaiser, James L

2009-01-01

In the United States, many fish and wildlife species have been used nationwide to monitor environmental contaminant exposure and effects, including carcasses of the bald eagle (Haliaeetus leucocephalus), the only top avian predator regularly used in the past. Unfortunately, bald eagles are sensitive to investigator intrusion at the nest. Thus, the osprey (Pandion haliaetus) is evaluated as a potential sentinel species for aquatic ecosystems. Several characteristics support the choice of the osprey as a sentinel species, including: (1) fish-eating diet atop the aquatic food web, (2) long-lived with strong nest fidelity, (3) adapts to human landscapes (potentially the most contaminated), (4) tolerates short-term nest disturbance, (5) nests spatially distributed at regular intervals, (6) highly visible nests easily located for study, (7) ability to accumulate most, if not all, lipophilic contaminants, (8) known sensitivity to many contaminants, and (9) nearly a worldwide distribution. These osprey traits have been instrumental in successfully using the species to understand population distribution, abundance, and changes over time; the effects of various contaminants on reproductive success; how contaminants in prey (fish on biomass basis) contribute to egg concentrations (i.e., biomagnification factors); and spatial residue patterns. Data summarized include nesting population surveys, detailed nesting studies, and chemical analyses of osprey egg, organ, blood, and feather samples for contaminants that bioaccumulate and/or biomagnify in aquatic food webs; and biochemical evaluations of blood and various organs. Studies in the United States, Canada, Mexico, Europe, and elsewhere have shown the osprey to be a useful sentinel species for monitoring selected environmental contaminants, including some emerging contaminants in lakes, reservoirs, rivers, and estuaries.

Osprey distribution, abundance, and status in western North America: I. The northern California population

USGS Publications Warehouse

Henny, Charles J.; Dunaway, David J.; Mallette, Robert D.; Koplin, James R.

1978-01-01

An estimated 355± 40 pairs (95 percent C.I.) of Ospreys (Pandion haliaetus carolinensis) nested in the northern California survey area in 1975. Eighty-one pairs were estimated along the extreme northern coast in Del Norte and Humboldt Counties. One hundred and forty-four pairs were estimated along California's northern coast in Mendociuo, Sonoma, and Marin Counties. The northern interior region, primarily in Siskiyou, Trinity, Shasta, Lassen, and Plumas Counties, contained an estimated 130 pairs. Forty-nine percent of the interior Osprey population is associated with reservoirs that were not present in 1900. We believe more Ospreys are present in the interior now than 75 years ago because of the increase in suitable habitat; nevertheless, populations at Shasta Lake and Clair Engle Lake are now exhibiting below-normal production rates and local declines. The long-term status of the coastal population, nesting along rivers, streams, and bays, is not clear. Recent production rates from two segments of the coastal population appear to be normal, but production at Usal Creek is below normal.

Examination of contaminant exposure and reproduction of ospreys (Pandion haliaetus) nesting in Delaware Bay and River in 2015.

PubMed

Rattner, Barnett A; Lazarus, Rebecca S; Bean, Thomas G; McGowan, Peter C; Callahan, Carl R; Erickson, Richard A; Hale, Robert C

2018-05-22

A study of ospreys (Pandion haliaetus) nesting in the coastal Inland Bays of Delaware, and the Delaware Bay and Delaware River in 2015 examined spatial and temporal trends in contaminant exposure, food web transfer and reproduction. Concentrations of organochlorine pesticides and metabolites, polychlorinated biphenyls (PCBs), coplanar PCB toxic equivalents, polybrominated diphenyl ethers (PBDEs) and other flame retardants in sample eggs were generally greatest in the Delaware River. Concentrations of legacy contaminants in 2015 Delaware Bay eggs were lower than values observed in the 1970s through early 2000s. Several alternative brominated flame retardants were rarely detected, with only TBPH [bis(2-ethylhexyl)-tetrabromophthalate)] present in 5 of 27 samples at <5 ng/g wet weight. No relation was found between p,p'-DDE, total PCBs or total PBDEs in eggs with egg hatching, eggs lost from nests, nestling loss, fledging and nest success. Osprey eggshell thickness recovered to pre-DDT era values, and productivity was adequate to sustain a stable population. Prey fish contaminant concentrations were generally less than those in osprey eggs, with detection frequencies and concentrations greatest in white perch (Morone americana) from Delaware River compared to the Bay. Biomagnification factors from fish to eggs for p,p'-DDE and total PCBs were generally similar to findings from several Chesapeake Bay tributaries. Overall, findings suggest that there have been improvements in Delaware Estuary waterbird habitat compared to the second half of the 20th century. This trend is in part associated with mitigation of some anthropogenic contaminant threats. Copyright © 2018 Elsevier B.V. All rights reserved.

Contaminants in ospreys from the Pacific Northwest: II. Organochlorine pesticides, polychlorinated biphenyls and mercury, 1991-1997

USGS Publications Warehouse

Elliott, J.E.; Macmer, M.M.; Wilson, L.K.; Henny, Charles J.

2000-01-01

Eggs of ospreys (Pandion haliaetus) were collected over the period 1991 to 1997 at 111 nests in the Fraser and Columbia River drainage systems of British Columbia, Washington, and Oregon. Contents were analyzed for organochlorine (OC) pesticides, polychlorinated biphenyls (PCBs), and total mercury. Blood samples were taken from nestling ospreys at two time points during the 1992 breeding season on the Thompson River and analyzed for non-ortho PCBs. Concentrations of DDE and related compounds showed high variability among individual eggs within study areas and no significant differences in mean concentrations among study areas. Some eggs contained high concentrations of DDE, up to 20 mg/kg (wet weight), for which there were no evident local sources, suggesting that exposure occurred outside of the breeding grounds. Most other OC pesticides measured in osprey eggs showed a similar distribution, although mean concentrations of chlordane-related compounds were generally, and in some cases significantly, higher in samples collected from the Columbia River sites compared to elsewhere. Significantly greater concentrations of PCBs were found in eggs from the Columbia River basin compared to the Fraser. This was attributed to extensive development of hydroelectric generation and related industries on the Columbia system. Significant differences among sites were also found in the pattern of PCB congeners, e.g., eggs from the lower Columbia River site had proportionally greater concentrations of less chlorinated, Aroclor 1242–type PCBs compared to other sites. In contrast, eggs from upper reaches of the Columbia River had relatively greater amounts of Aroclor 1254 and 1260 congeners. Mercury concentrations in osprey eggs tended to be uniform among sites and comparable to those reported in the literature for ospreys nesting on naturally formed lakes and rivers. There were no significant temporal changes in mean concentrations of any of the measured compounds at sites

Contaminants in ospreys from the Pacific Northwest: II. Organochlorine pesticides, polychlorinated biphenyls, and mercury, 1991-1997.

PubMed

Elliott, J E; Machmer, M M; Wilson, L K; Henny, C J

2000-01-01

Eggs of ospreys (Pandion haliaetus) were collected over the period 1991 to 1997 at 111 nests in the Fraser and Columbia River drainage systems of British Columbia, Washington, and Oregon. Contents were analyzed for organochlorine (OC) pesticides, polychlorinated biphenyls (PCBs), and total mercury. Blood samples were taken from nestling ospreys at two time points during the 1992 breeding season on the Thompson River and analyzed for non-ortho PCBs. Concentrations of DDE and related compounds showed high variability among individual eggs within study areas and no significant differences in mean concentrations among study areas. Some eggs contained high concentrations of DDE, up to 20 mg/kg (wet weight), for which there were no evident local sources, suggesting that exposure occurred outside of the breeding grounds. Most other OC pesticides measured in osprey eggs showed a similar distribution, although mean concentrations of chlordane-related compounds were generally, and in some cases significantly, higher in samples collected from the Columbia River sites compared to elsewhere. Significantly greater concentrations of PCBs were found in eggs from the Columbia River basin compared to the Fraser. This was attributed to extensive development of hydroelectric generation and related industries on the Columbia system. Significant differences among sites were also found in the pattern of PCB congeners, e.g., eggs from the lower Columbia River site had proportionally greater concentrations of less chlorinated, Aroclor 1242-type PCBs compared to other sites. In contrast, eggs from upper reaches of the Columbia River had relatively greater amounts of Aroclor 1254 and 1260 congeners. Mercury concentrations in osprey eggs tended to be uniform among sites and comparable to those reported in the literature for ospreys nesting on naturally formed lakes and rivers. There were no significant temporal changes in mean concentrations of any of the measured compounds at sites monitored

Contaminant exposure and reproductive success of Ospreys (Pandion haliaetus) nesting in Chesapeake Bay regions of concern

USGS Publications Warehouse

Rattner, B.A.; McGowan, P.C.; Golden, N.H.; Hatfield, J.S.; Toschik, P.C.; Lukei, R.F.; Hale, R.C.; Schmitz-Afonso, I.; Rice, C.P.

2004-01-01

The Chesapeake Bay osprey population has more than doubled in size since restrictions were placed on the production and use of DDT and other toxic organochlorine contaminants in the 1970s. Ospreys are now nesting in the most highly polluted portions of the Bay. In 2000 and 2001, contaminant exposure and reproduction were monitored in ospreys nesting in regions of concern, including Baltimore Harbor and the Patapsco River, the Anacostia and middle Potomac rivers, and the Elizabeth River, and a presumed reference site consisting of the South, West, and Rhode rivers. A 'sample egg' from each study nest was collected for contaminant analysis, and the fate of eggs remaining in each nest (n = 14-16/site) was monitored at 7- to 10-day intervals from egg incubation through fledging of young. Ospreys fledged young in regions of concern (observed success: 0.88 -1.53 fledglings/active nest), although productivity was marginal for sustaining local populations in Baltimore Harbor and the Patapsco River and in the Anacostia and middle Potomac rivers. Concentrations of p,p'DDE and many other organochlorine pesticides or metabolites, total PCBs, some arylhydrocarbon receptor-active PCB congeners and polybrominated diphenyl ether congeners, and perfluorooctanesulfonate were often greater in sample eggs from regions of concern compared to the reference site. Nonetheless, logistic regression analyses did not provide evidence linking marginal productivity to p,p' -DDE, total PCBs, or arylhydrocarbon receptor-active PCB congener exposure in regions of concern. In view of the moderate concentrations of total PCBs in eggs from the reference site, concerns related to new and emerging toxicants, and the absence of ecotoxicological data for terrestrial vertebrates in many Bay tributaries, a more thorough spatial evaluation of contaminant exposure in ospreys throughout the Chesapeake may be warranted.

22 CFR 228.34 - Joint ventures.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Joint ventures. 228.34 Section 228.34 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND NATIONALITY FOR COMMODITIES AND SERVICES FINANCED BY USAID Conditions Governing the Nationality of Suppliers of Services for USAID...

A comparison of mercury levels in feathers and eggs of osprey (Pandion haliaetus) in the North American Great Lakes.

PubMed

Hughes, K D; Ewins, P J; Clark, K E

1997-11-01

Osprey (Pandion haliaetus) eggs and chick feathers were collected for mercury analysis from nests at four Great Lakes study areas in Ontario (three "naturally formed" lakes in southern Ontario and one reservoir in northern Ontario) and two New Jersey study areas in 1991-1994. Adult osprey feathers were sampled from three Great Lakes study areas in 1991. Feathers sampled from chicks (approximately 28-35 days old) appear to be better indicators of local contaminant conditions since spatial patterns of mercury in known prey, yellow perch (Perca flavescens), also collected in these areas, were more similar to chick feathers than to eggs. Mercury levels were less variable in chick feathers than in eggs. Estimates of biomagnification factors using prey of known size at these areas were also less variable in feathers than in eggs. At naturally formed lakes, no significant correlation in mercury levels between eggs and chick feathers from the same nest was apparent, suggesting that the source of mercury contamination was not the same in these two tissues: mercury levels in eggs reflect mercury acquired on the breeding grounds, wintering grounds, and migratory route; mercury levels in chick feathers reflect local dietary conditions on the breeding grounds. Mercury levels in both osprey eggs and chick feathers were higher at the Ogoki Reservoir than at naturally formed lakes. Adult osprey feathers had higher mercury concentrations than chick feathers. Mercury levels in osprey eggs, chick feathers, and adult feathers did not approach levels associated with toxic reproductive effects.

Comparison of PFASs contamination in the freshwater and terrestrial environments by analysis of eggs from osprey (Pandion haliaetus), tawny owl (Strix aluco), and common kestrel (Falco tinnunculus).

PubMed

Eriksson, Ulrika; Roos, Anna; Lind, Ylva; Hope, Kjell; Ekblad, Alf; Kärrman, Anna

2016-08-01

The level of PFAS (per- and polyfluorinated alkyl substances) contamination in freshwater and terrestrial Swedish environments in 2013/2014 was assessed by analyzing a range of perfluorinated alkyl acids, fluorotelomer acids, sulfonamides, sulfonamidoethanols and polyfluoralkyl phosphate diesters (diPAPs) in predator bird eggs. Stable isotopes ((13)C and (15)N) were analyzed to elucidate the dietary source. The tawny owl (Strix aluco, n=10) and common kestrel (Falco tinnunculus, n=40), two terrestrial species, and the osprey (Pandion haliaetus, n=30), a freshwater specie were included. In addition, a temporal trend (1997-2001, 2008-2009, 2013) in osprey was studied as well. The PFAS profile was dominated by perfluorooctane sulfonic acid (PFOS) in eggs from osprey and tawny owl, while for common kestrel perfluorinated carboxylic acids (∑PFCA) exceeded the level of PFOS. PFOS concentration in osprey eggs remained at the same level between 1997 and 2001 and 2013. For the long-chained PFCAs, there were a significant increase in concentrations in osprey eggs between 1997 and 2001 and 2008-2009. The levels of PFOS and PFCAs were about 10 and five times higher, respectively, in osprey compared to tawny owl and common kestrel. Evidence of direct exposure from PFCA precursor compounds to birds in both freshwater and terrestrial environment was observed. Low levels of diPAPs were detected in a few samples of osprey (<0.02-2.4ng/g) and common kestrel (<0.02-0.16ng/g) eggs, and 6:2 FTSA was detected in a majority of the osprey eggs (<6.3-52ng/g). One saturated telomer acid (7:3 FTCA), which is a transformation marker from precursor exposure, was detected in all species (<0.24-2.7ng/g). The (15)N data showed higher levels in osprey eggs compared to tawny owl and common kestrel, indicating that they feed on a 2-3 times higher trophic level. We conclude that ospreys are continuously exposed to PFAS at levels where adverse toxic effects have been observed in birds. Copyright �

Osprey distribution, abundance, reproductive success and contaminant burdens along lower Columbia River, 1997/1998 versus 2004

USGS Publications Warehouse

Henny, C.J.; Grove, R.A.; Kaiser, J.L.

2008-01-01

The osprey (Pandion haliaetus) population nesting along the lower portion of the Columbia River (river mile 29 to 286) increased from 94 in 1997 to 103 occupied nests in 1998 (9.6% annual rate of increase) to 225 occupied nests in 2004 (13.9% annual rate of increase). The more recent rate of population increase was associated with higher reproductive rates than in 1997/1998, and significantly lower egg concentrations of most organochlorine (OC) pesticides, polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). A comparison of observed egg residue concentrations in 2004 with effect-level information for ospreys indicated that reproduction at few, if any, nests was adversely affected. As recent as 1997/1998, dichlorodiphenyldichloroethylene (DDE) was still adversely affecting reproductive success for a portion of this population. Mercury was the only contaminant evaluated in both 1997/1998 and 2004 that showed a significant increase in eggs over time, but concentrations in 2004 (0.09 ??g g -1 ww) remained below established effect levels for birds (generally reported at 0.50 ??g g-1 ww or higher). The significant increase in mercury justifies the need for future monitoring. All contaminants mentioned that biomagnify up food chains can be effectively monitored in osprey eggs. The osprey has been shown to be an excellent sentinel species for long-term monitoring with their many useful traits described. ?? 2007 Springer Science+Business Media, LLC.

Polybrominated diphenyl ether flame retardants in eggs may reduce reproductive success of ospreys in Oregon and Washington, USA.

PubMed

Henny, Charles J; Kaiser, James L; Grove, Robert A; Johnson, Branden L; Letcher, Robert J

2009-10-01

Spatial and temporal assessments and reports of polybrominated diphenyl ether (PBDE) flame retardants in birds remain sparse. In the present study, PBDEs were detected in all 120 osprey (Pandion haliaetus) eggs collected. The eggs were collected from nests along the Columbia, Willamette and Yakima rivers of Oregon (OR) and Washington (WA) and in Puget Sound (WA) between 2002 and 2007. PBDE congeners: 17, 28, 47, 49, 66, 85, 99, 100, 138, 153, 154 (possible coelution with brominated biphenyl 153 [BB153]), 183, 190 (detected in one egg), 209 (not detected), and BB101 (only detected in 2006 and 2007) and total-alpha-hexabromocyclododecane (only detected in five eggs) were analyzed for in the egg samples. Eggs from reservoirs in the forested headwaters of the Willamette River (2002) contained the lowest concentrations of SigmaPBDEs (geometric mean [range], 98 [55.2-275] ng/g wet weight [ww]), while those from the middle Willamette River (2006) contained the highest (897 [507-1,880] ng/g ww). Concentrations in eggs from the Columbia River progressively increased downstream from Umatilla, OR (River Mile [RM] 286) to Skamokoa, WA (RM 29), which indicated additive PBDE sources along the river. In general, regardless of the year of egg collection, differences in PBDE concentrations reported in osprey eggs along the three major rivers studied (Columbia, Willamette and Yakima) seem to reflect differences in river flow (dilution effect) and the extent of human population and industry (source inputs) along the rivers. PBDE concentrations increased over time at two locations (Seattle, WA; Columbia River, RM 29-84) where temporal patterns could be evaluated. Only during 2006 (on the middle Willamette River, RM 61-157) and 2007 (on the lower Columbia River, RM 29-84) did SigmaPBDE concentrations in osprey eggs exceed 1,000 ng/g ww with negative relationships indicated at both locations between productivity and SigmaPBDE concentrations in eggs (P = 0.008, P = 0.057). Osprey eggs

Polybrominated diphenyl ether flame retardants in eggs may reduce reproductive success of ospreys in Oregon and Washington, USA

USGS Publications Warehouse

Henny, C.J.; Kaiser, J.L.; Grove, R.A.; Johnson, B.L.; Letcher, R.J.

2009-01-01

Spatial and temporal assessments and reports of polybrominated diphenyl ether (PBDE) flame retardants in birds remain sparse. In the present study, PBDEs were detected in all 120 osprey (Pandion haliaetus) eggs collected. The eggs were collected from nests along the Columbia, Willamette and Yakima rivers of Oregon (OR) and Washington (WA) and in Puget Sound (WA) between 2002 and 2007. PBDE congeners: 17, 28, 47, 49, 66, 85, 99, 100, 138, 153, 154 (possible coelution with brominated biphenyl 153 [BB153]), 183, 190 (detected in one egg), 209 (not detected), and BB101 (only detected in 2006 and 2007) and total-??-hexabromocyclododecane (only detected in five eggs) were analyzed for in the egg samples. Eggs from reservoirs in the forested headwaters of the Willamette River (2002) contained the lowest concentrations of ???PBDEs (geometric mean [range], 98 [55.2-275] ng/g wet weight [ww]), while those from the middle Willamette River (2006) contained the highest (897 [507-1,880] ng/g ww). Concentrations in eggs from the Columbia River progressively increased downstream from Umatilla, OR (River Mile [RM] 286) to Skamokoa, WA (RM 29), which indicated additive PBDE sources along the river. In general, regardless of the year of egg collection, differences in PBDE concentrations reported in osprey eggs along the three major rivers studied (Columbia, Willamette and Yakima) seem to reflect differences in river flow (dilution effect) and the extent of human population and industry (source inputs) along the rivers. PBDE concentrations increased over time at two locations (Seattle, WA; Columbia River, RM 29-84) where temporal patterns could be evaluated. Only during 2006 (on the middle Willamette River, RM 61-157) and 2007 (on the lower Columbia River, RM 29-84) did ???PBDE concentrations in osprey eggs exceed 1,000 ng/g ww with negative relationships indicated at both locations between productivity and ???PBDE concentrations in eggs (P = 0.008, P = 0.057). Osprey eggs from

Comparison of PFASs contamination in the freshwater and terrestrial environments by analysis of eggs from osprey (Pandion haliaetus), tawny owl (Strix aluco), and common kestrel (Falco tinnunculus)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eriksson, Ulrika, E-mail: ulrika.eriksson@oru.se; Roos, Anna; Lind, Ylva

The level of PFAS (per- and polyfluorinated alkyl substances) contamination in freshwater and terrestrial Swedish environments in 2013/2014 was assessed by analyzing a range of perfluorinated alkyl acids, fluorotelomer acids, sulfonamides, sulfonamidoethanols and polyfluoralkyl phosphate diesters (diPAPs) in predator bird eggs. Stable isotopes ({sup 13}C and {sup 15}N) were analyzed to elucidate the dietary source. The tawny owl (Strix aluco, n=10) and common kestrel (Falco tinnunculus, n=40), two terrestrial species, and the osprey (Pandion haliaetus, n=30), a freshwater specie were included. In addition, a temporal trend (1997–2001, 2008–2009, 2013) in osprey was studied as well. The PFAS profile was dominatedmore » by perfluorooctane sulfonic acid (PFOS) in eggs from osprey and tawny owl, while for common kestrel perfluorinated carboxylic acids (∑PFCA) exceeded the level of PFOS. PFOS concentration in osprey eggs remained at the same level between 1997 and 2001 and 2013. For the long-chained PFCAs, there were a significant increase in concentrations in osprey eggs between 1997 and 2001 and 2008–2009. The levels of PFOS and PFCAs were about 10 and five times higher, respectively, in osprey compared to tawny owl and common kestrel. Evidence of direct exposure from PFCA precursor compounds to birds in both freshwater and terrestrial environment was observed. Low levels of diPAPs were detected in a few samples of osprey (<0.02–2.4 ng/g) and common kestrel (<0.02–0.16 ng/g) eggs, and 6:2 FTSA was detected in a majority of the osprey eggs (<6.3–52 ng/g). One saturated telomer acid (7:3 FTCA), which is a transformation marker from precursor exposure, was detected in all species (<0.24–2.7 ng/g). The {sup 15}N data showed higher levels in osprey eggs compared to tawny owl and common kestrel, indicating that they feed on a 2–3 times higher trophic level. We conclude that ospreys are continuously exposed to PFAS at levels where adverse toxic effects

OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design.

PubMed

Ojewole, Adegoke; Lowegard, Anna; Gainza, Pablo; Reeve, Stephanie M; Georgiev, Ivelin; Anderson, Amy C; Donald, Bruce R

2017-01-01

Drug resistance in protein targets is an increasingly common phenomenon that reduces the efficacy of both existing and new antibiotics. However, knowledge of future resistance mutations during pre-clinical phases of drug development would enable the design of novel antibiotics that are robust against not only known resistant mutants, but also against those that have not yet been clinically observed. Computational structure-based protein design (CSPD) is a transformative field that enables the prediction of protein sequences with desired biochemical properties such as binding affinity and specificity to a target. The use of CSPD to predict previously unseen resistance mutations represents one of the frontiers of computational protein design. In a recent study (Reeve et al. Proc Natl Acad Sci U S A 112(3):749-754, 2015), we used our OSPREY (Open Source Protein REdesign for You) suite of CSPD algorithms to prospectively predict resistance mutations that arise in the active site of the dihydrofolate reductase enzyme from methicillin-resistant Staphylococcus aureus (SaDHFR) in response to selective pressure from an experimental competitive inhibitor. We demonstrated that our top predicted candidates are indeed viable resistant mutants. Since that study, we have significantly enhanced the capabilities of OSPREY with not only improved modeling of backbone flexibility, but also efficient multi-state design, fast sparse approximations, partitioned continuous rotamers for more accurate energy bounds, and a computationally efficient representation of molecular-mechanics and quantum-mechanical energy functions. Here, using SaDHFR as an example, we present a protocol for resistance prediction using the latest version of OSPREY. Specifically, we show how to use a combination of positive and negative design to predict active site escape mutations that maintain the enzyme's catalytic function but selectively ablate binding of an inhibitor.

Ospreys do not teach offspring how to kill prey at the nest.

PubMed

Howard, Megan; Hoppitt, Will

2017-08-01

There is strong evidence for teaching in only a handful of species, most of which are cooperative breeders, leading some researchers to suggest that teaching may be more likely to evolve in such species. Alternatively, this initial distribution could be an artefact of the popularity and tractability of cooperative breeders as behavioural study systems. Therefore, establishing or refuting this potential evolutionary link requires researchers to assess potential cases of teaching in more non-cooperatively breeding species. We tested for teaching in the osprey ( Pandion haliaetus ), a non-cooperatively-breeding bird anecdotally reported to teach hunting skills to their offspring. We tested whether parents brought back more live prey to the nest as their offspring got older, allowing the latter to practice killing prey in a manner analogous to the progressive teaching seen in meerkats. We found the opposite trend to that predicted by the teaching hypothesis, indicating that ospreys do not teach their young at the nest. © 2017 The Author(s).

Chlorinated hydrocarbon contamination in osprey eggs and nestlings from the Canadian Great Lakes basin, 1991-1995.

PubMed

Martin, Pamela A; De Solla, Shane R; Ewins, Peter

2003-01-01

Populations of osprey (Pandion haliaetus) in the Great Lakes basin declined dramatically during the 1950s-1970s due largely to adverse effects of persistent chlorinated hydrocarbons, ingested in their fish prey, on eggshell thickness and adult survival. Nevertheless, these contaminants were not measured in osprey tissues during the decades of decline on the Canadian Great Lakes. Between 1991 and 1995, we monitored recovering osprey populations on the Great Lakes, including Georgian Bay and the St. Marys River area on Lake Huron and the St. Lawrence Islands National Park, as well as at two inland sites within the basin. Current OC levels, even from the most contaminated lakes, were typically lower than those associated with reproductive effects. DDE levels in fresh eggs averaged 1.2-2.9 microg/g, well below the 4.2 microg/g level associated with significant eggshell thinning and shell breakage. Nevertheless, a proportion of eggs from all study areas did exceed this level. PCB levels in eggs seldom exceeded 5 microg/g except in one lake of high breeding density in the Kawartha Lakes inland study area, where the mean sum PCB level was 7.1 microg/g and the maximum concentration measured was 26.5 microg/g. On average, mean reproductive output (0.78-2.75 young per occupied nest) of breeding populations in Great Lakes basin study areas exceeded the threshold of 0.8 young thought necessary to maintain stable populations. We concluded that, although eggs and especially nestling plasma, are useful in reflecting local contaminant levels, ospreys are relatively insensitive, at least at the population level, to health effects of current levels of chlorinated hydrocarbons on the Canadian Great Lakes.

Decadal re-evaluation of contaminant exposure and productivity of ospreys (Pandion haliaetus) nesting in Chesapeake Bay Regions of Concern.

PubMed

Lazarus, Rebecca S; Rattner, Barnett A; McGowan, Peter C; Hale, Robert C; Schultz, Sandra L; Karouna-Renier, Natalie K; Ottinger, Mary Ann

2015-10-01

The last large-scale ecotoxicological study of ospreys (Pandion haliaetus) in Chesapeake Bay was conducted in 2000-2001 and focused on U.S. EPA-designated Regions of Concern (ROCs; Baltimore Harbor/Patapsco, Anacostia/middle Potomac, and Elizabeth Rivers). In 2011-2012, ROCs were re-evaluated to determine spatial and temporal trends in productivity and contaminants. Concentrations of p,p'-DDE were low in eggs and below the threshold associated with eggshell thinning. Eggs from the Anacostia/middle Potomac Rivers had lower total PCB concentrations in 2011 than in 2000; however, concentrations remained unchanged in Baltimore Harbor. Polybrominated diphenyl ether flame retardants declined by 40%, and five alternative brominated flame retardants were detected at low levels. Osprey productivity was adequate to sustain local populations, and there was no relation between productivity and halogenated contaminants. Our findings document continued recovery of the osprey population, declining levels of many persistent halogenated compounds, and modest evidence of genetic damage in nestlings from industrialized regions. Published by Elsevier Ltd.

Decadal re-evaluation of contaminant exposure and productivity of ospreys (Pandion haliaetus) nesting in Chesapeake Bay Regions of Concern

USGS Publications Warehouse

Lazarus, Rebecca S.; Rattner, Barnett A.; McGowan, Peter C.; Hale, Robert C.; Schultz, Sandra; Karouna-Renier, Natalie K.; Ottinger, Mary Ann

2015-01-01

The last large-scale ecotoxicological study of ospreys (Pandion haliaetus) in Chesapeake Bay was conducted in 2000-2001 and focused on U.S. EPA-designated Regions of Concern (ROCs; Baltimore Harbor/Patapsco, Anacostia/middle Potomac, and Elizabeth Rivers). In 2011-2012, ROCs were re-evaluated to determine spatial and temporal trends in productivity and contaminants. Concentrations of p,p'-DDE were low in eggs and below the threshold associated with eggshell thinning. Eggs from the Anacostia/middle Potomac Rivers had lower total PCB concentrations in 2011 than in 2000; however, concentrations remained unchanged in Baltimore Harbor. Polybrominated diphenyl ether flame retardants declined by 40%, and five alternative brominated flame retardants were detected at low levels. Osprey productivity was adequate to sustain local populations, and there was no relation between productivity and halogenated contaminants. Our findings document continued recovery of the osprey population, declining levels of many persistent halogenated compounds, and modest evidence of genetic damage in nestlings from industrialized regions.

Research, management, and status of the osprey in North America

USGS Publications Warehouse

Henny, C.J.; Chancellor, R.D.

1977-01-01

Osprey populations were studied throughout North America during the last decade as a result of dramatic declines reported along the North Atlantic Coast in the1950s and early 1960s. Researchers used banding, localized studies, aerial surveys, and pesticide analyses to identify factors influencing regional populations. Declining populations showed extremely poor production, contamination by environmental pollutants (including DDT and its metabolites, dieldrin, and polychlorinated biphenyls) and thin-shelled eggs. Following the reduced use and eventual ban of DDT and dieldrin, productivity began to improve. Improvement in affected populations, mainly those along the Atlantic Coast and in the Great Lakes region, began in the late 1960s and is continuing in the 1970s. Most populations in the South Atlantic region, in Western North America, and in Florida and the Gulf of California appeared to be producing at normal or near-normal rates in the late 1960s and early 1970s. Although some of the most severely affected populations are still not producing at normal rates, the pattern of improvement and an increase in management activities, including provision of nesting platforms and establishment of Osprey management zones, allow cautious optimism about the future of the species in North America. With its low recruitment potential, however, recovery will be slow.

PCDDs, PCDFs, PCBs, OC pesticides and mercury in fish and osprey eggs from Willamette River, Oregon (1993, 2001 and 2006) with calculated biomagnification factors

USGS Publications Warehouse

Henny, C.J.; Kaiser, J.L.; Grove, R.A.

2009-01-01

The osprey (Pandion haliaetus) population nesting along the main stem Willamette River and lower Santiam River was first studied to evaluate contaminants and reproductive rates in 1993 when 78 occupied nests were present. By 2001, the population increased to 234 occupied nests, a 13.7% annual rate of population increase. A sample egg was collected from each of a series of nests along the Upper River (river mile 55-187) in 1993, 2001 and 2006 to evaluate trends of persistent contaminants (organochlorine [OC] pesticides, polychlorinated biphenyls [PCBs], polychlorinated dibenzo-p-dioxins [PCDDs], and polychlorinated dibenzofurans [PCDFs]). Nearly all OC pesticide residues decreased significantly, e.g., p, p?-DDE (DDE) from 2,350 to 1,353 to 210 ??g/kg wet weight (ww). PCBs followed a similar pattern over time, e.g., ???PCBs 688 to 245 to 182 ??g/kg ww, while PCDDs and PCDFs showed a more precipitous decline (often 85-95%) between 1993 and 2001, with no egg analyses warranted in 2006. During 2001-2002, sample osprey eggs were also collected from nests at three Headwater Reservoirs and two lower reaches (Newberg Pool and Tidal Portland) of the Willamette River, as well as the lower portion of the Santiam River to evaluate spatial residue patterns. Significant differences were seldom detected among the different sampling areas for OC pesticides (probably due to small sample sizes), although higher concentrations were often seen in the lower reaches, e.g., DDE 901 ??g/kg ww (Headwater Reservoirs), 1,353 (Upper River), 1,384 (Newberg Pool) and 2,676 (Tidal Portland). PCB congener concentrations in eggs were usually higher in the Tidal Portland reach than at other locations and often significantly higher than at the Headwater Reservoirs or Upper River. Mercury (first analyzed in eggs in 2001), PCDDs and PCDFs were extremely low in 2001/2002 with no significant spatial patterns. Whole fish composite samples of largescale sucker (Catastomus macrocheilus) and northern

Region-wide trends of nesting ospreys in northwestern Mexico: a three-decade perspective

USGS Publications Warehouse

Henny, Charles J.; Anderson, Daniel W.; Vera, Aradit Castellanos; Cartron, Jean-Luc E.

2008-01-01

We used a double-sampling technique (air plus ground survey) in 2006, with partial double coverage, to estimate the present size of the Osprey (Pandion haliaetus) nesting population in northwestern Mexico (coastal Baja California, islands in the Gulf of California, and coastal Sonora and Sinaloa). With the exception of Natividad, Cedros, and San Benitos islands along the Pacific coast of Baja California (all three excluded from our coverage in 2006 due to fog), this survey was a repeat of previous surveys conducted by us with the same protocol in 1977 and 1992/1993, allowing for estimates of regional population trends. The minimum population estimate for the area we surveyed in 2006 was 1343 nesting pairs, an 81% increase since 1977, but only a 3% increase since 1992/1993. The population on the Gulf side of Baja California generally remained stable during the three surveys (255, 236, and 252 pairs, respectively). The population of the Midriff Islands (Gulf of California in the vicinity of 29°N latitude) remained similar from 1992/1993 (308 pairs) to 2006 (289 pairs), but with notable population changes on the largest two islands (Guardian Angel: 45 to 105 pairs [133% increase]; Tiburón: 164 to 109 pairs [34% decrease]). The minimum estimated Osprey population on the Sonora mainland decreased in a manner similar to adjacent Isla Tiburón, i.e., by 26%, from 214 pairs in 1993 to 158 pairs in 2006. In contrast, the population in coastal Sinaloa, which had increased by 150% between 1977 and 1993, grew again by 58% between 1993 and 2006, from 180 to 285 pairs. Our survey confirmed previously described patterns of rapid population changes at a local level, coupled with apparent shifts in spatial distribution. The large ground-nesting population that until recently nested on two islands in San Ignacio Lagoon ( Pacific Ocean side, Baja California) was no longer present on the islands in 2006, but an equivalent number of pairs were found to the north and south of the

Experimental and Modeling Damage Limits Study for Straight Ti-3A1-2.5V Tubes

DTIC Science & Technology

2007-05-15

Titanium Tubes used in V-22 Osprey Tilt-rotor Aircraft ………………………………………………………………………………………..60 Appendix A. Project Presentation Slides – 1. Summary of...removed from the aircraft. By laboratory testing, finite element analysis and fracture mechanics study, damage limit curves of the titanium tubes have...OD) and 0.032” tube wall thickness (TWT) were studied, the impulse pressure test results for laser micromachining notched straight titanium tubes

Mercury and other Mining-Related Contaminants in Ospreys along the Upper Clark Fork River, MT

NASA Astrophysics Data System (ADS)

Langner, H.; Domenech, R.; Greene, E.; Staats, M. F.

2010-12-01

Osprey (Pandion haliaetus) are widely recognized as bio-indicators of the health of aquatic ecosystems. Until the time of fledging, nestlings feed exclusively on fish caught within a few kilometers of the nest. Therefore, tissues of these young birds may reflect the level of contamination of local fish and more generally, the contamination status of the aquatic ecosystem they inhabit. Nests can often be accessed with a boom truck and obtaining small blood samples from the flightless chicks is fairly noninvasive. Ospreys are nesting along the Upper Clark Fork River, Montana, which is heavily contaminated with wastes left from a century of copper and precious metals mining. We have been monitoring the levels of priority pollutants (arsenic, cadmium, lead, copper, zinc, mercury and selenium) in Osprey chicks along a 250 km section of the river for four years. Objectives are to establish current contaminant status, pinpoint pollution hotspots, and assess the success of restoration efforts. Our results suggest that of highest concern may be the bioaccumulation of mercury with blood levels of up to 0.7 mg/L in the growing chicks. These concentrations are expected to increase many fold upon fledging as feather growth stops, which acts as the major sink for mercury. Interestingly, we found mercury levels increased in downstream direction, in contrast to concentrations of other pollutants. Reasons may be the different origin of mercury versus other contaminants and the distribution of wetlands where mercury can be transformed into highly bioavailable methylmercury. Blood levels of selenium are also elevated throughout the Upper Clark Fork River drainage. We discuss the implications for restoration and remediation of the Clark Fork River.

In vitro V(D)J recombination: signal joint formation.

PubMed

Cortes, P; Weis-Garcia, F; Misulovin, Z; Nussenzweig, A; Lai, J S; Li, G; Nussenzweig, M C; Baltimore, D

1996-11-26

The first step of V(D)J recombination, specific cleavage at the recombination signal sequence (RSS), can be carried out by the recombination activating proteins RAG1 and RAG2. In vivo, the cleaved coding and signal ends must be rejoined to generate functional antigen receptors and maintain chromosomal integrity. We have investigated signal joint formation using deletion and inversion substrates in a cell free system. RAG1 and RAG2 alone or in combination were unable to generate signal joints. However, RAG1 and RAG2 complemented with nuclear extracts were able to recombine an extrachromosomal substrate and form precise signal joints. The in vitro reaction resembled authentic V(D)J recombination in being Ku-antigen-dependent.

U.S. Marine Corps Concepts & Programs 2009

DTIC Science & Technology

2009-01-01

war efforts in the CENTCOM AOR — that will demand balanced apportionment of limited re- sources . In this, the Marine Corps has identified four...Strike Fighter (JSF) Transition Plan 123 MV-22 Osprey Program 125 H-1 Upgrade (UH-1Y Huey/AH-1Z Cobra) 127 KC-130 Hercules 129 CH-53K Heavy Lift...leading joint-service development of our light, medium and heavy tactical wheeled vehicles for the joint force. The Expeditionary Fighting Vehicle (EFV

KENNEDY SPACE CENTER, FLA. -- A breeding osprey occupies a nest constructed on a speaker pole in the lower parking lot of the KSC Press Site. Eggs have been sighted in the nest. The NASA logo in the background is painted on an outer wall of the 525-foot-tall Vehicle Assembly Building nearby. Known as a fish hawk, the osprey selects sites of opportunity in which to nest -- from trees and telephone poles to rocks or even flat ground. In North America, it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

NASA Image and Video Library

2004-01-14

KENNEDY SPACE CENTER, FLA. -- A breeding osprey occupies a nest constructed on a speaker pole in the lower parking lot of the KSC Press Site. Eggs have been sighted in the nest. The NASA logo in the background is painted on an outer wall of the 525-foot-tall Vehicle Assembly Building nearby. Known as a fish hawk, the osprey selects sites of opportunity in which to nest -- from trees and telephone poles to rocks or even flat ground. In North America, it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

Fatigue strength: effect of welding type and joint design executed in Ti-6Al-4V structures.

PubMed

Pantoja, Juliana M C Nuñez; Farina, Ana P; Vaz, Luis G; Consani, Rafael L X; Nóbilo, Mauro A de Arruda; Mesquita, Marcelo F

2012-06-01

This study evaluated the fatigue strength of Ti-6Al-4V-machined structures submitted to laser (L)-welding and TIG (TIG)-welding procedures, varying the joint designs. Seventy dumbbell rods were machined in Ti-6Al-4V alloy with central diameters of 3.5 mm. The specimens were sectioned and welded using TIG or L and three joint designs {'I' design, varying welding distances [0.0 mm (I00) or 0.6 mm (I06)], or 'X' [X] design}. The combinations of variables created six groups, which, when added to the intact group, made a total of seven groups (n = 10). L was executed as follows: 360 V/8 ms (X) and 390 V/9 ms (I00 and I06), with focus and frequency regulated to zero. TIG was executed using 2:2 (X) and 3:2 (I00 and I06) as welding parameters. Joints were finished, polished and submitted to radiographic examination to be analysed visually for the presence of porosity. The specimens were then subjected to mechanical cyclic tests, and the number of cycles completed until failure was recorded. The fracture surface was examined using a scanning electron microscope. The Kruskal-Wallis and Dunn test (α = 0.05) indicated that the number of cycles resisted for fracture was higher to X for both welding procedures. To L, I06 was as resistant as X. The Mann-Whitney U-test (α = 0.05) indicated that L joints were more resistant than TIG to I00 and I06. Spearman's correlation coefficient (α = 0.05) indicated a negative correlation between the number of cycles and presence of porosity. Thus, to weld Ti-6Al-4V structures, the best condition is X, independent of the welding method employed. © 2011 The Gerodontology Society and John Wiley & Sons A/S.

Osprey distribution, abundance, and status in western North America: III. The Baja California and Gulf of California population

USGS Publications Warehouse

Henny, C.J.; Anderson, D.W.

1979-01-01

-An estimated 810 ? 55 pairs (minimum estimate) of ospreys (Pandion haliaetus) were nesting in the study area during our survey (24 March-l April 1977). Approximately 174 pairs nested along the Pacific side of Baja California, 255 pairs along the gulf side, 187 pairs on the Midriff Islands, and 194 pairs in coastal Sonora and Sinaloa. Most nested on cliffs adjacent to the sea (59%); some nested on cactus in flat terrain (26%). Seven per cent nested on the ground, three percent nested in mangroves and other trees in the southern portion of the study area,.and four percent nested on man-made structures. The extreme northwestern Baja California population that was extirpated early in this century has not recovered. However, several populations immediately to the south along the Pacific Coast now appear stationary. Pesticide residues in osprey eggs from Mexico were among the lowest reported for the species in North America.

KENNEDY SPACE CENTER, FLA. -- A pair of breeding ospreys share a nest constructed on a speaker pole in the lower parking lot of the KSC Press Site. Eggs have been sighted in the nest. The NASA logo in the background is painted on an outer wall of the 525-foot-tall Vehicle Assembly Building nearby. Known as a fish hawk, the osprey selects sites of opportunity in which to nest -- from trees and telephone poles to rocks or even flat ground. In North America, it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

NASA Image and Video Library

2004-01-14

KENNEDY SPACE CENTER, FLA. -- A pair of breeding ospreys share a nest constructed on a speaker pole in the lower parking lot of the KSC Press Site. Eggs have been sighted in the nest. The NASA logo in the background is painted on an outer wall of the 525-foot-tall Vehicle Assembly Building nearby. Known as a fish hawk, the osprey selects sites of opportunity in which to nest -- from trees and telephone poles to rocks or even flat ground. In North America, it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

KENNEDY SPACE CENTER, FLA. -- A pair of breeding ospreys have taken up residence in a nest constructed on a speaker pole in the lower parking lot of the KSC Press Site. Eggs have been sighted in the nest. The NASA logo in the background is painted on an outer wall of the 525-foot-tall Vehicle Assembly Building nearby. Known as a fish hawk, the osprey selects sites of opportunity in which to nest -- from trees and telephone poles to rocks or even flat ground. In North America, it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

NASA Image and Video Library

2004-01-14

KENNEDY SPACE CENTER, FLA. -- A pair of breeding ospreys have taken up residence in a nest constructed on a speaker pole in the lower parking lot of the KSC Press Site. Eggs have been sighted in the nest. The NASA logo in the background is painted on an outer wall of the 525-foot-tall Vehicle Assembly Building nearby. Known as a fish hawk, the osprey selects sites of opportunity in which to nest -- from trees and telephone poles to rocks or even flat ground. In North America, it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

Osprey distribution, abundance, and status in western North America: II. The Oregon population

USGS Publications Warehouse

Henny, C.J.; Collins, J.A.; Deibert, W.J.

1978-01-01

An estimated 308 ? 23 pairs of Ospreys nested in the survey area in Oregon in 1976. Major concentration centers include Crane Prairie Reservoir and the adjacent Deschutes National Forest, the coastal lakes and reservoirs between Florence and North Bend, the Rogue River, the Lane County reservoirs, and the Umpqua River. An estimated 47 percent of the Oregon population is nesting at reservoirs. Limited information is available concerning the long-term status of the Oregon population; however, the ability of the species to pioneer newly created reservoirs emphasizes that the population is utilizing new habitats.

Radiographic inspection of porosity in Ti-6Al-4V laser-welded joints.

PubMed

Nuñez-Pantoja, Juliana Maria Costa; Takahashi, Jessica Mie Ferreira Koyama; Nóbilo, Mauro Antônio de Arruda; Consani, Rafael Leonardo Xediek; Mesquita, Marcelo Ferraz

2011-01-01

Widely used in dentistry, Ti-6Al-4V alloy is difficult to cast and solder, as it frequently exhibits pores inside the structure. This study was conducted to evaluate the effect of joint openings and diameters of laser-welded joints executed in Ti-6Al-4V structures on the presence of pores as checked by radiographic procedures. Sixty dumbbell rods with central diameters of 1.5, 2.0 and 3.5 mm were created from Ti-6Al-4V-wrought bars. Specimens were sectioned and welded using two joint openings (0.0 and 0.6 mm). The combination of variables created six groups (n = 10). Laser welding was executed using 360V/8ms (1.5 and 2.0 mm) and 380V/9ms (3.5 mm), with the focus and frequency set to zero. The joints were finished, polished and submitted to radiographic examination. The radiographs were visually examined for the presence of pores in the joints, qualitatively. The percentage of radiographic presence of pores was calculated without counting pores per joint. Data were analyzed using a chi-square test (α = 0.05). For the 1.5-mm specimens, the incidence of pore presence was significantly higher (p = 0.0001) when using 0.6-mm joint openings (40%) compared to 0.0-mm openings (0%). For the 2.0-mm specimens, there was no significant difference between groups (p = 0.2008). However, for the 3.5-mm specimens, the incidence of pore presence was lower (p = 0.0061) for 0.6-mm openings (50%) compared to 0.0-mm openings (70%). Therefore, laser welding of Ti-6Al-4V structures with thin diameters provides the best condition for the juxtaposition of the parts.

Incidence of organochlorine pesticides and the health condition of nestling ospreys (Pandion haliaetus) at Laguna San Ignacio, a pristine area of Baja California Sur, Mexico.

PubMed

Rivera-Rodríguez, Laura B; Rodríguez-Estrella, Ricardo

2011-01-01

We identified and quantified organochlorine (OC) pesticide residues in the plasma of 28 osprey (Pandion haliaetus) nestlings from a dense population in Laguna San Ignacio, a pristine area of Baja California Sur, Mexico, during the 2001 breeding season. Sixteen OC pesticides were identified and quantified. α-, β-, δ- and γ-hexachlorocyclohexane, heptaclor, heptachlor epoxide, endosulfan I and II, endosulfan-sulfate, p,p'-DDE, p,p'-DDD, aldrin, dieldrin, endrin, endrin aldehyde, and endrin ketone were the OCs found in the plasma of nestlings, ranging from 0.002 to 6.856 pg/μl (parts per billion). No differences were found in the concentration of pesticides between genders (P > 0.05). In our work, the concentrations detected in the plasma were lower than those reported to be a threat for the species and that affect the survival and reproduction of birds. The presence of OC pesticides in the remote Laguna San Ignacio osprey population is an indication of the ubiquitous nature of these contaminants. OCs are apparently able to travel long distances from their source to the study area. A significant relationship between hemoglobin and mean corpuscular hemoglobin concentrations and OC concentrations were found suggesting that a potential effect on the health of chicks may exist in this osprey population caused by the OC, e.g. anemia. The total proteins were positively correlated with α-BHC, endosulfan I, and p,p'-DDD. It has been suggested that OC also affects competitive interactions and population status over the long term in vertebrate species, and our results could be used as reference information for comparison with other more exposed osprey populations.

Open capsular and ligament reconstruction with semitendinosus hamstring autograft successfully controls superior and posterior translation for type V acromioclavicular joint dislocation.

PubMed

Garofalo, Raffaele; Ceccarelli, Enrico; Castagna, Alessandro; Calvisi, Vittorio; Flanagin, Brody; Conti, Marco; Krishnan, Sumant G

2017-07-01

Appropriate surgical management for type V complete acromioclavicular (AC) joint dislocation remains controversial. The purpose of this paper is to retrospectively report the clinical and radiographic outcomes of an open surgical technique consisting for AC joint ligamentous and capsular reconstruction using autologous hamstring tendon grafts and semi-permanent sutures. Between January 2005 and December 2011, 32 consecutive patients with symptomatic type V complete AC joint dislocation underwent surgical treatment using the same technique. The median time from injury to surgery was 45 days (range 24-90). The average median postoperative clinical and radiographic follow-up time was 30 months (range 24-33). Clinical outcomes measures included the ASES score, the visual analog score (VAS), and subjective patient satisfaction score. Minimum follow-up was 2 years. ASES score increased from a median of 38.2 ± 6.2 preoperative to 92.1 ± 4.7 postoperatively (p ≤ 0.05). The median VAS score improved from 62 mm (range 45-100 mm) preoperatively to 8 mm (range 0-20 mm) at final follow-up (p ≤ 0.05). No patient experienced pain or discomfort with either direct palpation of the AC joint or with cross-body adduction. Final radiographs demonstrated symmetric AC joint contour in 25/32 (78%) patients. Seven patients (22%) radiographically demonstrated superior translation of the distal clavicle relative to the superior margin of the acromion but less than 50% of the clavicular width. 30/32 patients (93%) were able to return to their pre-injury level of work and sports activities. This novel surgical technique using a free graft and braided suture for simultaneous coracoclavicular ligament and AC joint capsular reconstruction successfully controls superior and posterior translations after type V AC joint dislocation and minimizes the incidence of persistent postoperative AC joint subluxation. Retrospective case series, Level IV.

Th1/Th17/Th22 immune response and their association with joint pain, imagenological bone loss, RANKL expression and osteoclast activity in temporomandibular joint osteoarthritis: A preliminary report.

PubMed

Monasterio, G; Castillo, F; Rojas, L; Cafferata, E A; Alvarez, C; Carvajal, P; Núñez, C; Flores, G; Díaz, W; Vernal, R

2018-05-15

It is well accepted that the presence of cytokines belonging to the Th1/Th17/Th22 axis of immuno-inflammatory response in the joint environment, such as IL-1β, IL-17 and IL-22, respectively, are associated with pathogenesis of several synovial joint degenerative disorders. During temporomandibular joint osteoarthritis (TMJ-OA), IL-1β and IL-17 have been implicated in the inflammation and resorption of sub-chondral bone; however, the role of Th22 response in the TMJ-OA pathophysiology has not been established. This study aimed to compare the expression of Th1/Th17/Th22-type cytokines, chemokines and chemokine receptors in synovial fluid samples obtained from TMJ-OA or disk displacement with reduction (DDWR) patients. In addition, it aimed to associate these levels with joint pain, imagenological signs of bone degeneration, RANKL production, osteoclastogenesis and osteoclast-induced bone resorption. Higher levels of IL-1β, IL-17 and IL-22 were expressed in TMJ-OA compared with DDWR subjects, and these increased levels significantly correlated with RANKL expression, joint pain and articular bone degeneration. Higher levels of CCR5, CCR6 and CCR7, as well as their respective ligands CCL5 and CCL20, responsible for recruitment of IL-1β, IL-17 and IL-22-producing cells, were over-expressed in TMJ-OA compared with DDWR subjects. Osteoclastogenesis and osteoclast-induced bone resorption were significantly greater in presence of synovial fluid from TMJ-OA compared with DDWR subjects. These data demonstrate that cytokines, CCLs and CCRs associated with the Th1/Th17/Th22 axis of immuno-inflammatory response are involved in TMJ-OA pathogenesis. These findings suggest that IL-22 is involved in the RANKL expression in TMJ-OA, which in turn induces differentiation of osteoclasts and subsequent resorption of sub-chondral bone. © 2018 John Wiley & Sons Ltd.

Dachtal Isomers and Acidic Herbicides and Pesticides in Eggs of Osprey (Pandion haliaetus) from the Seattle and Everett Areas, Washington, U.S.A

USGS Publications Warehouse

Chu, S.; Henny, Charles J.; Kaiser, James L.; Drouillard, K.G.; Haffner, G.D.; Letcher, R.J.

2007-01-01

Current-use chlorophenoxy herbicides including 2,4-dichlorophenoxyacetic acid, dicamba, triclopyr, dicamba, dimethyl tetrachloroterephthalate (DCPA or dacthal), and the metabolite of pyrethroids, 3-phenoxybenzoic acid (3-PBA), and the fungicide, chlorothalonil, were investigated in the eggs of osprey (Pandion haliaetus) that were collected from 15 sites from five study areas Puget Sound/Seattle area of Washington State, USA. DCPA differs from acidic chlorophenoxy herbicides, and is not readily hydrolyzed to free acid or acid metabolites, and thus we developed a new method. Of the 12 chlorophenoxy herbicides and chlorothalonil analyzed only DCPA could be quantified at six of these sites (2.0 to 10.3 pg/g fresh weight). However, higher levels (6.9 to 85.5 pg/g fresh weight) of the unexpected DCPA structural isomer, dimethyl tetrachlorophthalate (diMe-TCP) were quantified in eggs from all sites. diMe-TCP concentrations tended to be higher in eggs from the Everett Harbor area. As diMe-TCP is not an industrial product, and not commercially available, the source of diMe-TCP is unclear. Regardless, these findings indicate that DCPA and diMe-TCP can be accumulated in the food chain of fish-eating osprey, and transferred in ovo to eggs, and thus may be of concern to the health of the developing chick and the general reproductive health of this osprey population.

Population size and trends for nesting ospreys in northwestern Mexico: Region-wide surveys, 1977, 1992/1993 and 2006

USGS Publications Warehouse

Henny, Charles J.; Anderson, Daniel W.; Vera, Aradit Castellanos; Carton, Jean-Luc E.

2007-01-01

We used a double-sampling technique (air plus ground survey) in 2006, with partial double coverage, to estimate the present size of the osprey (Pandion haliaetus) nesting population in northwestern Mexico. With the exception of Natividad, Cedros, and San Benito Islands along the Pacific Coast of Baja California, all three excluded from our coverage in 2006 due to fog, this survey was a repeat of previous surveys conducted by us with the same protocol in 1977 and 1992/1993 (Baja California surveyed in 1992, Sonora and Sinaloa 1993), allowing for estimates of regional population trends. Population estimates at the 'time of aerial survey' include those nesting, but missed from the air. The population estimate for our coverage area in 2006 was 1,343 nesting pairs, or an 81% increase since 1977, but only a 3% increase since 1992/1993. The population on the Gulf side of Baja California generally remained stable during the three surveys (255, 236 and 252 pairs, respectively). The overall Midriff Islands population remained similar from 1992/1993 (308 pairs) to 2006 (289 pairs), but with notable population changes on the largest two islands (Isla Angel de la Guarda: 45 to 105 pairs [+ 60 pairs]; Isla Tiburon: 164 to 109 pairs [- 55 pairs, or -34%]). The estimated osprey population on the Sonora mainland decreased in a manner similar to adjacent Isla Tiburon, i.e., by 26%, from 214 pairs in 1993 to 158 pairs in 2006. In contrast, the population in Sinaloa, which had increased by 150% between 1977 and 1993, grew again by 58% between 1993 and 2006, from 180 to 285 pairs. Our survey confirmed previously described patterns of rapid population changes at a local level, coupled with apparent shifts in spatial distribution. The large ground nesting population that until recently nested on two islands in San Ignacio Lagoon was no longer present on the islands in 2006, but an equivalent number of pairs were found to the north and south of the lagoon, nesting in small towns and along

A comparative study on the histological structure of the spleen in the ostrich (Struthio camelus), the kestrel (Falco tinnunculus) and the osprey (Pandion haliaetus).

PubMed

Kozlu, Tolunay; Karadag Sari, Ebru; Akaydin Bozkurt, Yesim; Altunay, H

2011-06-01

The spleen structurally and functionally belongs to the hematopoietic organs and is also an important component of the reticuloendothelial system, which is known to play a major role in host defense. The histological structure of the spleen was investigated in the ostrich, a non-flying bird, the kestrel, a raptor, and the osprey, a fish-eating bird of prey (fish eagle). For this purpose, Mallory's modified triple stain, methyl green-pyronin and silver stain were used. Germinal centers were not present in the spleen of the osprey. In the spleen of the kestrel, penicillar arterioles and the surrounding lymphoid tissue were markedly dense. Compared to the other two birds, the red and white pulps were clearly distinguishable in the spleen of the ostrich.

26 CFR 31.3121(v)(2)-2 - Effective dates and transition rules.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 26 Internal Revenue 15 2012-04-01 2012-04-01 false Effective dates and transition rules. 31.3121(v)(2)-2 Section 31.3121(v)(2)-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Provisions § 31.3121(v)(2)-2 Effective dates and transition rules. (a) General statutory effective date...

26 CFR 31.3121(v)(2)-2 - Effective dates and transition rules.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 26 Internal Revenue 15 2013-04-01 2013-04-01 false Effective dates and transition rules. 31.3121(v)(2)-2 Section 31.3121(v)(2)-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Provisions § 31.3121(v)(2)-2 Effective dates and transition rules. (a) General statutory effective date...

26 CFR 31.3121(v)(2)-2 - Effective dates and transition rules.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 26 Internal Revenue 15 2014-04-01 2014-04-01 false Effective dates and transition rules. 31.3121(v)(2)-2 Section 31.3121(v)(2)-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Provisions § 31.3121(v)(2)-2 Effective dates and transition rules. (a) General statutory effective date...

26 CFR 31.3121(v)(2)-2 - Effective dates and transition rules.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 26 Internal Revenue 15 2011-04-01 2011-04-01 false Effective dates and transition rules. 31.3121(v)(2)-2 Section 31.3121(v)(2)-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Provisions § 31.3121(v)(2)-2 Effective dates and transition rules. (a) General statutory effective date...

Microstructure and mechanical properties of diffusion bonded W/steel joint using V/Ni composite interlayer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, W.S.; Cai, Q.S., E-mail: cai2009pm@163.com; Ma, Y.Z.

2013-12-15

Diffusion bonding between W and steel using V/Ni composite interlayer was carried out in vacuum at 1050 °C and 10 MPa for 1 h. The microstructural examination and mechanical property evaluation of the joints show that the bonding of W to steel was successful. No intermetallic compound was observed at the steel/Ni and V/W interfaces for the joints bonded. The electron probe microanalysis and X-ray diffraction analysis revealed that Ni{sub 3}V, Ni{sub 2}V, Ni{sub 2}V{sub 3} and NiV{sub 3} were formed at the Ni/V interface. The tensile strength of about 362 MPa was obtained for as-bonded W/steel joint and themore » failure occurred at W near the V/W interface. The nano-indentation test across the joining interfaces demonstrated the effect of solid solution strengthening and intermetallic compound formation in the diffusion zone. - Highlights: • Diffusion bonding of W to steel was realized using V/Ni composite interlayer. • The interfacial microstructure of the joint was clarified. • Several V–Ni intermetallic compounds were formed in the interface region. • The application of V/Ni composite interlayer improved the joining quality.« less

Evaluation of INL Supplied MOOSE/OSPREY Model: Modeling Water Adsorption on Type 3A Molecular Sieve

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pompilio, L. M.; DePaoli, D. W.; Spencer, B. B.

The purpose of this study was to evaluate Idaho National Lab’s Multiphysics Object-Oriented Simulation Environment (MOOSE) software in modeling the adsorption of water onto type 3A molecular sieve (3AMS). MOOSE can be thought-of as a computing framework within which applications modeling specific coupled-phenomena can be developed and run. The application titled Off-gas SeParation and REcoverY (OSPREY) has been developed to model gas sorption in packed columns. The sorbate breakthrough curve calculated by MOOSE/OSPREY was compared to results previously obtained in the deep bed hydration tests conducted at Oak Ridge National Laboratory. The coding framework permits selection of various options, whenmore » they exist, for modeling a process. For example, the OSPREY module includes options to model the adsorption equilibrium with a Langmuir model or a generalized statistical thermodynamic adsorption (GSTA) model. The vapor solid equilibria and the operating conditions of the process (e.g., gas phase concentration) are required to calculate the concentration gradient driving the mass transfer between phases. Both the Langmuir and GSTA models were tested in this evaluation. Input variables were either known from experimental conditions, or were available (e.g., density) or were estimated (e.g., thermal conductivity of sorbent) from the literature. Variables were considered independent of time, i.e., rather than having a mass transfer coefficient that varied with time or position in the bed, the parameter was set to remain constant. The calculated results did not coincide with data from laboratory tests. The model accurately estimated the number of bed volumes processed for the given operating parameters, but breakthrough times were not accurately predicted, varying 50% or more from the data. The shape of the breakthrough curves also differed from the experimental data, indicating a much wider sorption band. Model modifications are needed to improve its utility and

DOD Supply Chain: Preliminary Observations Indicate That Counterfeit Electronic Parts Can Be Found on Internet Purchasing Platforms

DTIC Science & Technology

2011-11-08

Corps’ V-22 Osprey aircraft, and the Navy’s SSN-688 Los Angeles Class nuclear-powered attack submarine . If authentic, these parts provide accurate power...even d Different color epoxy seals were noted within both lots according to SMT Corp., which is common in suspect counterfeit devices

Optical Sensors for Planetary Radiant Energy (OSPREy): Calibration and Validation of Current and Next-Generation NASA Missions

NASA Technical Reports Server (NTRS)

Hooker, Stanford B.; Bernhard, Germar; Morrow, John H.; Booth, Charles R.; Comer, Thomas; Lind, Randall N.; Quang, Vi

2012-01-01

A principal objective of the Optical Sensors for Planetary Radiance Energy (OSPREy) activity is to establish an above-water radiometer system as a lower-cost alternative to existing in-water systems for the collection of ground-truth observations. The goal is to be able to make high-quality measurements satisfying the accuracy requirements for the vicarious calibration and algorithm validation of next-generation satellites that make ocean color and atmospheric measurements. This means the measurements will have a documented uncertainty satisfying the established performance metrics for producing climate-quality data records. The OSPREy approach is based on enhancing commercial-off-the-shelf fixed-wavelength and hyperspectral sensors to create hybridspectral instruments with an improved accuracy and spectral resolution, as well as a dynamic range permitting sea, Sun, sky, and Moon observations. Greater spectral diversity in the ultraviolet (UV) will be exploited to separate the living and nonliving components of marine ecosystems; UV bands will also be used to flag and improve atmospheric correction algorithms in the presence of absorbing aerosols. The short-wave infrared (SWIR) is expected to improve atmospheric correction, because the ocean is radiometrically blacker at these wavelengths. This report describes the development of the sensors, including unique capabilities like three-axis polarimetry; the documented uncertainty will be presented in a subsequent report.

Global Flowfield About the V-22 Tiltrotor Aircraft

NASA Technical Reports Server (NTRS)

Meakin, Robert L.

1996-01-01

This final report includes five publications that resulted from the studies of the global flowfield about the V-22 Tiltrotor Aircraft. The first of the five is 'The Chimera Method of Simulation for Unsteady Three-Dimensional Viscous Flow', as presented in 'Computational Fluid Dynamics Review 1995.' The remaining papers, all presented at AIAA conferences, are 'Unsteady Simulation of the Viscous Flow About a V-22 Rotor and Wing in Hover', 'An Efficient Means of Adaptive Refinement Within Systems of Overset Grids', 'On the Spatial and Temporal Accuracy of Overset Grid Methods for MOving Body Problems', and 'Moving Body Overset Grid Methods for Complete Aircraft Tiltrotor Simulations.'

Density dependence in a recovering osprey population: demographic and behavioural processes.

PubMed

Bretagnolle, V; Mougeot, F; Thibault, J-C

2008-09-01

1. Understanding how density-dependent and independent processes influence demographic parameters, and hence regulate population size, is fundamental within population ecology. We investigated density dependence in growth rate and fecundity in a recovering population of a semicolonial raptor, the osprey Pandion haliaetus [Linnaeus, 1758], using 31 years of count and demographic data in Corsica. 2. The study population increased from three pairs in 1974 to an average of 22 pairs in the late 1990s, with two distinct phases during the recovery (increase followed by stability) and contrasted trends in breeding parameters in each phase. 3. We show density dependence in population growth rate in the second phase, indicating that the stabilized population was regulated. We also show density dependence in productivity (fledging success between years and hatching success within years). 4. Using long-term data on behavioural interactions at nest sites, and on diet and fish provisioning rate, we evaluated two possible mechanisms of density dependence in productivity, food depletion and behavioural interference. 5. As density increased, both provisioning rate and the size of prey increased, contrary to predictions of a food-depletion mechanism. In the time series, a reduction in fledging success coincided with an increase in the number of non-breeders. Hatching success decreased with increasing local density and frequency of interactions with conspecifics, suggesting that behavioural interference was influencing hatching success. 6. Our study shows that, taking into account the role of non-breeders, in particular in species or populations where there are many floaters and where competition for nest sites is intense, can improve our understanding of density-dependent processes and help conservation actions.

Dacthal and chlorophenoxy herbicides and chlorothalonil fungicide in eggs of osprey (Pandion haliaetus) from the Duwamish-Lake Washington-Puget Sound area of Washington state, USA

USGS Publications Warehouse

Chu, S.; Henny, C.J.; Kaiser, J.L.; Drouillard, K.G.; Haffner, G.D.; Letcher, R.J.

2007-01-01

Current-use chlorophenoxy herbicides including 2,4-dichlorophenoxyacetic acid, dicamba, triclopyr, dicamba, dimethyl tetrachloroterephthalate (DCPA or dacthal), and the metabolite of pyrethroids, 3-phenoxybenzoic acid (3-PBA), and the fungicide, chlorothalonil, were investigated in the eggs of osprey (Pandion haliaetus) that were collected from 15 sites from five study areas Puget Sound/Seattle area of Washington State, USA. DCPA differs from acidic chlorophenoxy herbicides, and is not readily hydrolyzed to free acid or acid metabolites, and thus we developed a new method. Of the 12 chlorophenoxy herbicides and chlorothalonil analyzed only DCPA could be quantified at six of these sites (2.0 to 10.3 pg/g fresh weight). However, higher levels (6.9 to 85.5 pg/g fresh weight) of the unexpected DCPA structural isomer, dimethyl tetrachlorophthalate (diMe-TCP) were quantified in eggs from all sites. diMe-TCP concentrations tended to be higher in eggs from the Everett Harbor area. As diMe-TCP is not an industrial product, and not commercially available, the source of diMe-TCP is unclear. Regardless, these findings indicate that DCPA and diMe-TCP can be accumulated in the food chain of fish-eating osprey, and transferred in ovo to eggs, and thus may be of concern to the health of the developing chick and the general reproductive health of this osprey population. ?? 2006 Elsevier Ltd. All rights reserved.

Residues of environmental pollutants and necropsy data for eastern United States ospreys, 1964-1973

USGS Publications Warehouse

Wiemeyer, Stanley N.; Lamont, T.G.; Locke, L.N.

1980-01-01

Thirty-three ospreys (Pandion haliaetus) that were found dead or moribund in the Eastern United States between 1964 and 1973 were necropsied. The brains and carcasses of 26 of these birds were analyzed for organochlorines. The livers of 18 and the kidneys of 7 were analyzed for selected metals. Most adults were recovered in April and May and most immatures were recovered in August through October. The adult sex ratio was highly unbalanced in favor of females. Major causes of mortality were impact injuries, emaciation, shooting, and respiratory infections. Of special interest were two birds with malignant tumors and one with steatitis. Many birds had undergone marked weight losses resulting in mobilization and redistribution of organochlorine residues. Organochlorines were detected in the birds at the following percentages: DDE l00%, PCB 96%, DDD 92%, dieldrin 88%, chlordanes (including nonachlors) 82%, DDT 65%, and heptachlor epoxide 38%. Organochlorine levels tended to be higher in adults than in immatures. One adult from South Carolina had a potentially dangerous level of dieldrin in its brain, which might have contributed to its death. Immature ospreys from Maryland had extremely elevated levels of copper in their livers compared with immatures from other areas and all adults. One immature from Maryland had an elevated level of arsenic in its liver, which might have contributed to its death. One adult from Florida that had died of impact injuries had potentially dangerous levels of mercury in both liver and kidney and slightly elevated levels of cadmium in these tissues. Additional birds appeared to have been exposed to contamination of the environment by arsenic and mercury. The levels of chromium, zinc, and lead in livers appeared normal.

A novel large thrust-weight ratio V-shaped linear ultrasonic motor with a flexible joint.

PubMed

Li, Xiaoniu; Yao, Zhiyuan; Yang, Mojian

2017-06-01

A novel large thrust-weight ratio V-shaped linear ultrasonic motor with a flexible joint is proposed in this paper. The motor is comprised of a V-shaped transducer, a slider, a clamp, and a base. The V-shaped transducer consists of two piezoelectric beams connected through a flexible joint to form an appropriate coupling angle. The V-shaped motor is operated in the coupled longitudinal-bending mode. Longitudinal and bending movements are transferred by the flexible joint between the two beams. Compared with the coupled longitudinal-bending mode of the single piezoelectric beam or the symmetrical and asymmetrical modes of the previous V-shaped transducer, the coupled longitudinal-bending mode of the V-shaped transducer with a flexible joint provides higher vibration efficiency and more convenient mode conformance adjustment. A finite element model of the V-shaped transducer is created to numerically study the influence of geometrical parameters and to determine the final geometrical parameters. In this paper, three prototypes were then fabricated and experimentally investigated. The modal test results match well with the finite element analysis. The motor mechanical output characteristics of three different coupling angles θ indicate that V-90 (θ = 90°) is the optimal angle. The mechanical output experiments conducted using the V-90 prototype (Size: 59.4 mm × 30.7 mm × 4 mm) demonstrate that the maximum unloaded speed is 1.2 m/s under a voltage of 350 Vpp, and the maximum output force is 15 N under a voltage of 300 Vpp. The proposed novel V-shaped linear ultrasonic motor has a compact size and a simple structure with a large thrust-weight ratio (0.75 N/g) and high speed.

Knockdown of peroxiredoxin V increases glutamate‑induced apoptosis in HT22 hippocampal neuron cells.

PubMed

Shen, Gui-Nan; Liu, Lei; Feng, Li; Jin, Yu; Jin, Mei-Hua; Han, Ying-Hao; Jin, Cheng-Hao; Jin, Yong-Zhe; Lee, Dong-Soek; Kwon, Tae Ho; Cui, Yu-Dong; Sun, Hu-Nan

2018-06-01

High concentrations of glutamate may mediate neuronal cell apoptosis by increasing intracellular reactive oxygen species (ROS) levels. Peroxiredoxin V (Prx V), a member of the Prx family, serves crucial roles in protecting cells from oxidative stress. The present study investigated the regulatory effect of Prx V on glutamate‑induced effects on viability and apoptosis in HT22 cells. Western blotting was used for protein expression analysis and Annexin V/PI staining and flow cytometry for determination of apoptosis. The results demonstrated that glutamate may ROS‑dependently increase HT22 cell apoptosis and upregulate Prx V protein levels. Furthermore, knockdown of Prx V protein expression with a lentivirus significantly enhanced HT22 cell apoptosis mediated by glutamate, which was reversed by inhibition of ROS with N‑acetyl‑L‑cysteine. Inhibiting the extracellular signal‑regulated kinase (ERK) signaling pathway with PD98059, a specific inhibitor for ERK phosphorylation, markedly decreased glutamate‑induced HT22 cell apoptosis in Prx V knockdown cells, indicating the potential involvement of ERK signaling in glutamate‑induced HT22 cell apoptosis. In addition, an increase in nuclear apoptosis‑inducing factor was observed in Prx V knockdown HT22 cells following glutamate treatment, compared with mock cells, whereas no differences in B‑cell lymphoma‑2 and cleaved‑caspase‑3 protein expression levels were observed between mock and Prx V knockdown cells. The results of the present study indicated that Prx V may have potential as a therapeutic molecular target for glutamate‑induced neuronal cell death and provide novel insight into the role of Prx V in oxidative‑stress induced neuronal cell death.

Effect of Nd:YAG laser beam welding on weld morphology and mechanical properties of Ti-6Al-4V butt joints and T-joints

NASA Astrophysics Data System (ADS)

Kashaev, Nikolai; Ventzke, Volker; Fomichev, Vadim; Fomin, Fedor; Riekehr, Stefan

2016-11-01

A Nd:YAG single-sided laser beam welding process study for Ti-6Al-4V butt joints and T-joints was performed to investigate joining techniques with regard to the process-weld morphology relationship. An alloy compatible filler wire was used to avoid underfills and undercuts. The quality of the butt joints and T-joints was characterized in terms of weld morphology, microstructure and mechanical properties. Joints with regular shapes, without visible cracks, pores, and geometrical defects were achieved. Tensile tests revealed high joint integrity in terms of strength and ductility for both the butt joint and T-joint geometries. Both the butt joints and T-joints showed base material levels of strength. The mechanical performance of T-joints was also investigated using pull-out tests. The performance of the T-joints in such tests was sensitive to the shape and morphology of the welds. Fracture always occurred in the weld without any plastic deformation in the base material outside the weld.

Effect of Al-Si Coating on Weld Microstructure and Properties of 22MnB5 Steel Joints for Hot Stamping

NASA Astrophysics Data System (ADS)

Lin, Wenhu; Li, Fang; Wu, Dongsheng; Chen, Xiaoguan; Hua, Xueming; Pan, Hua

2018-03-01

22MnB5 hot stamping steels are gradually being used in tailor-welded blank applications. In this experiment, 1-mm-thick Al-Si coated and de-coated 22MnB5 steels were laser-welded and then hot-stamped. The chemical compositions, solidification process, microstructure and mechanical properties were investigated to reveal the effect of Al-Si coating and heat treatment. In the welded condition, the coated joints had an Al content of approximately 2.5 wt.% in the fusion zone and the de-coated joints had 0.5 wt.% Al. The aluminum promoted the δ-ferrite formation as the skeletal structure during solidification. In the high-aluminum weld, the microstructure consisted of martensite and long and band-like δ-ferrite. Meanwhile, the low-aluminum weld was full of lath martensite. After the hot stamping process, the δ-ferrite fraction increased from 10 to 24% in the coated joints and the lath martensite became finer in the de-coated joints. The tensile strengths of the coated joints or de-coated joints were similar to that before hot stamping, but the strength of the coated joints was reduced heavily after hot stamping compared to the de-coated joints and base material. The effect of δ-ferrite on the tensile properties became stronger when the fusion zone was soft and deformed first in the hot-stamped specimens. The coated weld showed a brittle fracture surface with many cleavage planes, and the de-coated weld showed a ductile fracture surface with many dimples in hot-stamped conditions.

A novel CaV2.2 channel inhibition by piracetam in peripheral and central neurons.

PubMed

Bravo-Martínez, Jorge; Arenas, Isabel; Vivas, Oscar; Rebolledo-Antúnez, Santiago; Vázquez-García, Mario; Larrazolo, Arturo; García, David E

2012-10-01

No mechanistic actions for piracetam have been documented to support its nootropic effects. Voltage-gated calcium channels have been proposed as a promising pharmacological target of nootropic drugs. In this study, we investigated the effect of piracetam on Ca(V)2.2 channels in peripheral neurons, using patch-clamp recordings from cultured superior cervical ganglion neurons. In addition, we tested if Ca(V)2.2 channel inhibition could be related with the effects of piracetam on central neurons. We found that piracetam inhibited native Ca(V)2.2 channels in superior cervical ganglion neurons in a dose-dependent manner, with an IC(50) of 3.4 μmol/L and a Hill coefficient of 1.1. GDPβS dialysis did not prevent piracetam-induced inhibition of Ca(V)2.2 channels and G-protein-coupled receptor activation by noradrenaline did not occlude the piracetam effect. Piracetam altered the biophysical characteristics of Ca(V)2.2 channel such as facilitation ratio. In hippocampal slices, piracetam and ω-conotoxin GVIA diminished the frequency of excitatory postsynaptic potentials and action potentials. Our results provide evidence of piracetam's actions on Ca(V)2.2 channels in peripheral neurons, which might explain some of its nootropic effects in central neurons.

22. V2 GANTRY, LAUNCH COMPLEX 33: GENERAL VIEW, LOOKING WEST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. V-2 GANTRY, LAUNCH COMPLEX 33: GENERAL VIEW, LOOKING WEST AND UPWARD FROM APRON OF BLAST PIT, 20,000 POUND MOTOR TEST AND LAUNCH FACILITY - White Sands Missile Range, V-2 Rocket Facilities, Near Headquarters Area, White Sands, Dona Ana County, NM

β-Subunits Promote the Expression of CaV2.2 Channels by Reducing Their Proteasomal Degradation*

PubMed Central

Waithe, Dominic; Ferron, Laurent; Page, Karen M.; Chaggar, Kanchan; Dolphin, Annette C.

2011-01-01

The β-subunits of voltage-gated calcium channels regulate their functional expression and properties. Two mechanisms have been proposed for this, an effect on gating and an enhancement of expression. With respect to the effect on expression, β-subunits have been suggested to enhance trafficking by masking an unidentified endoplasmic reticulum (ER) retention signal. Here we have investigated whether, and how, β-subunits affect the level of CaV2.2 channels within somata and neurites of cultured sympathetic neurons. We have used YFP-CaV2.2 containing a mutation (W391A), that prevents binding of β-subunits to its I-II linker and found that expression of this channel was much reduced compared with WT CFP-CaV2.2 when both were expressed in the same neuron. This effect was particularly evident in neurites and growth cones. The difference between the levels of YFP-CaV2.2(W391A) and CFP-CaV2.2(WT) was lost in the absence of co-expressed β-subunits. Furthermore, the relative reduction of expression of CaV2.2(W391A) compared with the WT channel was reversed by exposure to two proteasome inhibitors, MG132 and lactacystin, particularly in the somata. In further experiments in tsA-201 cells, we found that proteasome inhibition did not augment the cell surface CaV2.2(W391A) level but resulted in the observation of increased ubiquitination, particularly of mutant channels. In contrast, we found no evidence for selective retention of CaV2.2(W391A) in the ER, in either the soma or growth cones. In conclusion, there is a marked effect of β-subunits on CaV2.2 expression, particularly in neurites, but our results point to protection from proteasomal degradation rather than masking of an ER retention signal. PMID:21233207

Technetium-99m-labeled annexin V imaging for detecting prosthetic joint infection in a rabbit model.

PubMed

Tang, Cheng; Wang, Feng; Hou, Yanjie; Lu, Shanshan; Tian, Wei; Xu, Yan; Jin, Chengzhe; Wang, Liming

2015-05-01

Accurate and timely diagnosis of prosthetic joint infection is essential to initiate early treatment and achieve a favorable outcome. In this study, we used a rabbit model to assess the feasibility of technetium-99m-labeled annexin V for detecting prosthetic joint infection. Right knee arthroplasty was performed on 24 New Zealand rabbits. After surgery, methicillin-susceptible Staphylococcus aureus was intra-articularly injected to create a model of prosthetic joint infection (the infected group, n = 12). Rabbits in the control group were injected with sterile saline (n = 12). Seven and 21 days after surgery, technetium-99m-labeled annexin V imaging was performed in 6 rabbits of each group. Images were acquired 1 and 4 hours after injection of technetium-99m-labeled annexin V (150 MBq). The operated-to-normal-knee activity ratios were calculated for quantitative analysis. Seven days after surgery, increased technetium-99m-labeled annexin V uptake was observed in all cases. However, at 21 days a notable decrease was found in the control group, but not in the infected group. The operated-to-normal-knee activity ratios of the infected group were 1.84 ± 0.29 in the early phase and 2.19 ± 0.34 in the delay phase, both of which were significantly higher than those of the control group (P = 0.03 and P = 0.02). The receiver operator characteristic curve analysis showed that the operated-to-normal-knee activity ratios of the delay phase at 21 days was the best indicator, with an accuracy of 80%. In conclusion, technetium-99m-labeled annexin V imaging could effectively distinguish an infected prosthetic joint from an uninfected prosthetic joint in a rabbit model.

Development and laboratory testing of a 138-kV PPP-insulated joint for commercial application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walldorf, S.P.; Chu, H.; Elbadaly, H.

1990-04-01

This paper describes the design, development and laboratory testing of a high voltage PPP (paper polypropylene/paper laminate) insulated joint for commercial application on 138-kV PPP-insulated cable. The design approach taken is conservative and addresses the typical variations in field conditions and in skill and workmanship of the splicing. Joint construction details, including choice of connector, taping structure, and joint mechanical reinforcement, are discussed. The test criteria are described and results are presented.

Concomitant glenohumeral pathologies associated with acute and chronic grade III and grade V acromioclavicular joint injuries.

PubMed

Jensen, Gunnar; Millett, Peter J; Tahal, Dimitri S; Al Ibadi, Mireille; Lill, Helmut; Katthagen, Jan Christoph

2017-08-01

The purpose of this study was to identify the risk of concomitant glenohumeral pathologies with acromioclavicular joint injuries grade III and V. Patients who underwent arthroscopically-assisted stabilization of acromioclavicular joint injuries grade III or grade V between 01/2007 and 12/2015 were identified in the patient databases of two surgical centres. Gender, age at index surgery, grade of acromioclavicular joint injury (Rockwood III or Rockwood V), and duration between injury and index surgery (classified as acute or chronic) were of interest. Concomitant glenohumeral pathologies were noted and their treatment was classified as debridement or reconstructive procedure. A total of 376 patients (336 male, 40 female) were included. Mean age at time of arthroscopic acromioclavicular joint reconstruction surgery was 42.1 ± 14.0 years. Overall, 201 patients (53%) had one or more concomitant glenohumeral pathologies. Lesions of the biceps tendon complex and rotator cuff were the most common. Forty-five patients (12.0%) had concomitant glenohumeral pathologies that required an additional repair. The remaining 156 patients (41.5%) received a debridement of their concomitant pathologies. Rockwood grade V compared to Rockwood grade III (p = 0.013; odds ratio 1.7), and chronic compared to acute injury were significantly associated with having a concomitant glenohumeral pathology (p = 0.019; odds ratio 1.7). The probability of having a concomitant glenohumeral pathology was also significantly associated with increasing age (p < 0.0001). Concomitant glenohumeral pathologies were observed in 53% of surgically treated patients with an acute or chronic acromioclavicular joint injury of either grade III or V. Twenty-two percent of these patients with concomitant glenohumeral pathologies received an additional dedicated repair procedure. Although a significant difference in occurrence of concomitant glenohumeral pathologies was seen between Rockwood grades III and V

Compressive Strength Evaluation in Brazed ZrO2/Ti6Al4V Joints Using Finite Element Analysis

NASA Astrophysics Data System (ADS)

Sharma, Ashutosh; Kee, Se Ho; Jung, Flora; Heo, Yongku; Jung, Jae Pil

2016-05-01

This study aims to synthesize and evaluate the compressive strength of the ZrO2/Ti-6Al-4V joint brazed using an active metal filler Ag-Cu-Sn-Ti, and its application to dental implants assuring its reliability to resist the compressive failure in the actual oral environment. The brazing was performed at a temperature of 750 °C for 30 min in a vacuum furnace under 5 × 10-6 Torr atmosphere. The microstructure of the brazed joint showed the presence of an Ag-rich matrix and a Cu-rich phase, and Cu-Ti intermetallic compounds were observed along the Ti-6Al-4V bonded interface. The compressive strength of the brazed ZrO2/Ti-6Al-4V joint was measured by EN ISO 14801 standard test method. The measured compressive strength of the joint was ~1477 MPa—a value almost five times that of existing dental cements. Finite element analysis also confirmed the high von Mises stress values. The compressive strains in the samples were found concentrated near the Ti-6Al-4V position, matching with the position of the real fractured sample. These results suggest extremely significant compressive strength in ZrO2/Ti-6Al-4V joints using the Ag-Cu-Sn-Ti filler. It is believed that a highly reliable dental implant can be processed and designed using the results of this study.

Alternative Splicing in CaV2.2 Regulates Neuronal Trafficking via Adaptor Protein Complex-1 Adaptor Protein Motifs

PubMed Central

Macabuag, Natsuko

2015-01-01

N-type voltage-gated calcium (CaV2.2) channels are expressed in neurons and targeted to the plasma membrane of presynaptic terminals, facilitating neurotransmitter release. Here, we find that the adaptor protein complex-1 (AP-1) mediates trafficking of CaV2.2 from the trans-Golgi network to the cell surface. Examination of splice variants of CaV2.2, containing either exon 37a (selectively expressed in nociceptors) or 37b in the proximal C terminus, reveal that canonical AP-1 binding motifs, YxxΦ and [DE]xxxL[LI], present only in exon 37a, enhance intracellular trafficking of exon 37a-containing CaV2.2 to the axons and plasma membrane of rat DRG neurons. Finally, we identify differential effects of dopamine-2 receptor (D2R) and its agonist-induced activation on trafficking of CaV2.2 isoforms. D2R slowed the endocytosis of CaV2.2 containing exon 37b, but not exon 37a, and activation by the agonist quinpirole reversed the effect of the D2R. Our work thus reveals key mechanisms involved in the trafficking of N-type calcium channels. SIGNIFICANCE STATEMENT CaV2.2 channels are important for neurotransmitter release, but how they are trafficked is still poorly understood. Here, we describe a novel mechanism for trafficking of CaV2.2 from the trans-Golgi network to the cell surface which is mediated by the adaptor protein AP-1. Alternative splicing of exon 37 produces CaV2.2-exon 37a, selectively expressed in nociceptors, or CaV2.2-exon 37b, which is the major splice isoform. Our study reveals that canonical AP-1 binding motifs (YxxΦ and [DE]xxxL[LI]), present in exon 37a, but not 37b, enhance intracellular trafficking of exon 37a-containing CaV2.2 to axons and plasma membrane of DRG neurons. Interaction of APs with CaV2.2 channels may also be key underlying mechanisms for differential effects of the dopamine D2 receptor on trafficking of CaV2.2 splice variants. PMID:26511252

Organochlorines and mercury in osprey eggs from the eastern United States

USGS Publications Warehouse

Audet, D.J.; Scott, D.S.; Wiemeyer, Stanley N.

1992-01-01

Organochlorine and mercury concentrations were determined in Osprey eggs collected from Maryland, Virginia, and Massachusetts during 1986-87. DDE concentrations were significantly different among locations. Median DDE concentrations did not decline significantly in eggs from Glenn L. Martin National Wildlife Refuge, Maryland, between 1973 and 1986. The median DDE residue for eggs from Martin Refuge in 1986 surpassed the value associated with 10% eggshell thinning, but was below the value associated with production of 1.0 young per active nest, a level assumed to represent a stable population. DDD, DDT, dieldrin, PCB, and mercury residues in all eggs appeared insignificant with regard to potential effects on shell thickness or reproduction. DDE and PCB residues were lower in eggs collected in 1986-87 than in those collected in the 1970s for each area. DDD, DDT, and dieldrin were not detected in Martin Refuge eggs in 1986, representing a significant reduction since 1973. DDD, DDT, and dieldrin levels in Massachusetts and Virginia eggs in 1986-87 were similar to those in eggs from the 1970s for each state. Mercury residues in eggs from Martin Refuge may be increasing and although not significant in this study, may warrant future monitoring.

A historical overview of tiltrotor aeroelastic research at Langley Research Center

NASA Technical Reports Server (NTRS)

Kvaternik, Raymond G.

1992-01-01

The Bell/Boeing V-22 Osprey which is being developed for the U.S. Military is a tiltrotor aircraft combining the versatility of a helicopter with the range and speed of a turboprop airplane. The V-22 represents a tiltrotor lineage which goes back over forty years, during which time contributions to the technology base needed for its development were made by both government and industry. NASA Langley Research Center has made substantial contributions to tiltrotor technology in several areas, in particular in the area of aeroelasticity. The purpose of this talk is to present a summary of the tiltrotor aeroelastic research conducted at Langley which has contributed to that technology.

DOD Supply Chain: Suspect Counterfeit Electronic Parts Can Be Found on Internet Purchasing Platforms

DTIC Science & Technology

2012-02-01

Parts Marine Corps’s V-22 Osprey aircraft, and the Navy’s SSN-688 Los Angeles Class nuclear-powered attack submarine . If authentic, these parts...authentication analyses. Visual inspection was performed on all evidence samples from both purchases. Different color epoxy seals were noted within both...including the ballistic missile early warning system, the Air Force’s Peacekeeper missile and B-1B aircraft, the Navy’s Trident submarine and Arleigh

Effects of laser-weld joint opening size on fatigue strength of Ti-6Al-4V structures with several diameters.

PubMed

Nuñez-Pantoja, J M C; Vaz, L G; Nóbilo, M A A; Henriques, G E P; Mesquita, M F

2011-03-01

This study was conducted to evaluate the fatigue strength of Ti-6Al-4V laser-welded joints with several diameters and joint openings. Sixty dumbbell rods were machined in Ti-6Al-4V alloy with central diameters of 1·5, 2·0 and 3·5 mm. The specimens were sectioned and then welded using two joint openings (0·0 and 0·6 mm). The combination of variables created six groups, which when added to the intact groups made a total of nine groups (n = 10). Laser welding was executed as follows: 360 V per 8 ms (1·5 and 2·0 mm) and 380 V per 9 ms (3·5 mm) with focus and frequency regulated to zero. The joints were finished, polished and submitted to radiographic examination to be analysed visually for the presence of porosity. The specimens were then subjected to a mechanical cyclic test, and the number of cycles until failure was recorded. The fracture surface was examined with a scanning electron microscope (SEM). The Kruskal-Wallis test and Dunn test (α = 0·05) indicated that the number of cycles required for fracture was lower for all specimens with joint openings of 0·6 mm, and for 3·5-mm-diameter specimens with joint openings of 0·0 mm. The Spearman correlation coefficient (α = 0·05) indicated that there was a negative correlation between the number of cycles and the presence of porosity. So, laser welding of Ti-6Al-4V structures with a thin diameter provides the best conditions for the juxtaposition of parts. Radiographic examination allows for the detection of internal voids in titanium joints. © 2010 Blackwell Publishing Ltd.

22 CFR 401.22 - Attendance of witnesses and production of documents.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Attendance of witnesses and production of documents. 401.22 Section 401.22 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.22 Attendance of witnesses and production of documents. (a...

22 CFR 401.22 - Attendance of witnesses and production of documents.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Attendance of witnesses and production of documents. 401.22 Section 401.22 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.22 Attendance of witnesses and production of documents. (a...

22 CFR 401.22 - Attendance of witnesses and production of documents.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Attendance of witnesses and production of documents. 401.22 Section 401.22 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.22 Attendance of witnesses and production of documents. (a...

22 CFR 401.22 - Attendance of witnesses and production of documents.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Attendance of witnesses and production of documents. 401.22 Section 401.22 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.22 Attendance of witnesses and production of documents. (a...

Contaminants in ospreys from the Pacific Northwest: I. Trends and Patterns in polychlorinated dibenzo-p-dioxins and -dibenzofurans in eggs and plasma

USGS Publications Warehouse

Elliott, J.E.; Machmer, M.M.; Henny, Charles J.; Wilson, L.K.; Norstrom, R.J.

1998-01-01

Osprey (Pandion haliaetus) eggs were collected from 1991 to 1997 at nests (na??=a??121) upstream and downstream of bleached kraft pulp mills and at reference sites in the Fraser and Columbia River drainage systems of British Columbia, Washington, and Oregon. Blood samples were collected from nestling ospreys during the 1992 breeding season on the Thompson River. Samples were analyzed for polychlorinated dibenzo-p-dioxins (PCDDs) and -dibenzofurans (PCDFs). Mean concentrations of 2,3,7,8-TCDD were significantly higher in eggs collected in 1991 at downstream compared to upstream nests near pulp mills at Kamloops and Castlegar, British Columbia. There were no significant temporal trends in 2,3,7,8-TCDD, -TCDF or other measured compounds at a sample of nests monitored between 1991 and 1994 downstream of the Castlegar pulp mill, despite changes in bleaching technology (CIO2 substitution). However, by 1997 concentrations of 2,3,7,8-TCDD and -TCDF were significantly lower than previous years in nests sampled downstream at both Castlegar and Kamloops. An unusual pattern of higher chlorinated PCDDs and PCDFs was found in many of the osprey eggs collected in this study, and considerable individual variation in the pattern existed among eggs from the same site. For example, eggs from four different nests at one study area (Quesnel) on the Fraser River had concentrations of 1,2,3,4,6,7,8-HpCDD ranging from <1 to 1,100 ng/kg and OCDD from <1 to 7,000 ng/kg wet weight. Higher mean concentrations of HpCDD and OCDD were found in eggs from the Thompson River, a tributary of the Fraser, compared to the Columbia River, and concentrations were generally higher at nests upstream of pulp mills. In plasma samples, 1,2,3,4,6,7,8-HpCDD and OCDD were the main compounds detected, with no significant differences measured between samples upstream versus downstream or earlier versus later in the breeding season. Use of chlorophenolic wood preservatives by lumber processors was considered the

Contaminants in ospreys from the Pacific Northwest: I. Trends and patterns in polychlorinated dibenzo-p-dioxins and -dibenzofurans in eggs and plasma.

PubMed

Elliott, J E; Machmer, M M; Henny, C J; Wilson, L K; Norstrom, R J

1998-11-01

Osprey (Pandion haliaetus) eggs were collected from 1991 to 1997 at nests (n = 121) upstream and downstream of bleached kraft pulp mills and at reference sites in the Fraser and Columbia River drainage systems of British Columbia, Washington, and Oregon. Blood samples were collected from nestling ospreys during the 1992 breeding season on the Thompson River. Samples were analyzed for polychlorinated dibenzo-p-dioxins (PCDDs) and -dibenzofurans (PCDFs). Mean concentrations of 2,3,7,8-TCDD were significantly higher in eggs collected in 1991 at downstream compared to upstream nests near pulp mills at Kamloops and Castlegar, British Columbia. There were no significant temporal trends in 2,3,7,8-TCDD, -TCDF or other measured compounds at a sample of nests monitored between 1991 and 1994 downstream of the Castlegar pulp mill, despite changes in bleaching technology (CIO2 substitution). However, by 1997 concentrations of 2, 3,7,8-TCDD and -TCDF were significantly lower than previous years in nests sampled downstream at both Castlegar and Kamloops. An unusual pattern of higher chlorinated PCDDs and PCDFs was found in many of the osprey eggs collected in this study, and considerable individual variation in the pattern existed among eggs from the same site. For example, eggs from four different nests at one study area (Quesnel) on the Fraser River had concentrations of 1,2,3,4,6,7,8-HpCDD ranging from <1 to 1,100 ng/kg and OCDD from <1 to 7,000 ng/kg wet weight. Higher mean concentrations of HpCDD and OCDD were found in eggs from the Thompson River, a tributary of the Fraser, compared to the Columbia River, and concentrations were generally higher at nests upstream of pulp mills. In plasma samples, 1,2,3,4,6,7,8-HpCDD and OCDD were the main compounds detected, with no significant differences measured between samples upstream versus downstream or earlier versus later in the breeding season. Use of chlorophenolic wood preservatives by lumber processors was considered the main

Increasing Ti-6Al-4V brazed joint strength equal to the base metal by Ti and Zr amorphous filler alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ganjeh, E., E-mail: navidganjehie@sina.kntu.ac.ir; Sarkhosh, H.; Bajgholi, M.E.

Microstructural features developed along with mechanical properties in furnace brazing of Ti-6Al-4V alloy using STEMET 1228 (Ti-26.8Zr-13Ni-13.9Cu, wt.%) and STEMET 1406 (Zr-9.7Ti-12.4Ni-11.2Cu, wt.%) amorphous filler alloys. Brazing temperatures employed were 900-950 Degree-Sign C for the titanium-based filler and 900-990 Degree-Sign C for the zirconium-based filler alloys, respectively. The brazing time durations were 600, 1200 and 1800 s. The brazed joints were evaluated by ultrasonic test, and their microstructures and phase constitutions analyzed by metallography, scanning electron microscopy and X-ray diffraction analysis. Since microstructural evolution across the furnace brazed joints primarily depends on their alloying elements such as Cu, Ni andmore » Zr along the joint. Accordingly, existence of Zr{sub 2}Cu, Ti{sub 2}Cu and (Ti,Zr){sub 2}Ni intermetallic compounds was identified in the brazed joints. The chemical composition of segregation region in the center of brazed joints was identical to virgin filler alloy content which greatly deteriorated the shear strength of the joints. Adequate brazing time (1800 s) and/or temperature (950 Degree-Sign C for Ti-based and 990 Degree-Sign C for Zr-based) resulted in an acicular Widmanstaetten microstructure throughout the entire joint section due to eutectoid reaction. This microstructure increased the shear strength of the brazed joints up to the Ti-6Al-4V tensile strength level. Consequently, Ti-6Al-4V can be furnace brazed by Ti and Zr base foils produced excellent joint strengths. - Highlights: Black-Right-Pointing-Pointer Temperature or time was the main factors of controlling braze joint strength. Black-Right-Pointing-Pointer Developing a Widmanstaetten microstructure generates equal strength to base metal. Black-Right-Pointing-Pointer Brittle intermetallic compounds like (Ti,Zr){sub 2}Ni/Cu deteriorate shear strength. Black-Right-Pointing-Pointer Ti and Zr base filler alloys were the best choice for

Experimental cryo-irrigation of the knee joint.

PubMed

Chen, S C; Helal, B; Revell, P A; Brocklehurst, R; Currey, H L

1986-10-01

Experiments have been carried out to test the feasibility of using cryo-irrigation as a means of ablating the synovium in the rheumatoid knee joint. Cryo-irrigation was performed by a cooling machine and pump, which circulated cold 200/10 centistoke (cSt) silicone through the knee joint of rabbits anaesthetised with intravenous (IV) 'Saffan'. Fluid left the joint at -5 to -10 degrees C. Sixteen normal New Zealand rabbits received cryo-irrigation of one knee joint for 10-20 minutes and were killed at one day, and one, two, and 12 weeks thereafter. Judged by radioactive sulphate incorporation there was no impairment of chondrocyte function in the articular cartilage of irrigated joints. Histological examination showed mild synovitis and some loss of staining of superficial cartilage in 6/16 irrigated joints (v 1/16 control joints). Similar treatment of rabbit joints in which the Glynn model of synovitis had been induced showed marked reduction of synovitis 14-45 days after silicone treatment. Nine of 26 animals in which synovitis was induced in both knees and cryo-irrigation performed in one knee died either immediately postoperatively or during the next week. These deaths remain unexplained. A single dog received cryo-irrigation of one knee (-6 to -9 degrees C for 22 min) and remained perfectly well up to sacrifice at six months, when the joint appeared histologically completely normal.

Novel thioarsenates {[Mn(2,2'-bipy)2(SCN)][Mn(2,2'-bipy)](As(V)S4)}2 and {[Mn(2,2'-bipy)2(SCN)]2[As(III)2(S2)2S2]}: introducing an anionic second ligand to modify MnII complex cations of 2,2'-bipyridine.

PubMed

Liu, Guang-Ning; Guo, Guo-Cong; Wang, Ming-Sheng; Huang, Jin-Shun

2014-03-14

Two novel manganese thioarsenates, {[Mn(2,2'-bipy)2(SCN)][Mn(2,2'-bipy)](As(V)S4)}2 (1, 2,2'-bipy = 2,2'-bipyridine) and {[Mn(2,2'-bipy)2(SCN)]2[As(III)2(S2)2S2]} (2), containing thiocyanate-modified Mn-2,2'-bipy complex cations were synthesized. They feature two terminal [Mn(2,2'-bipy)2(SCN)](+) complex cations bridged by a polyanion {[Mn(2,2'-bipy)]2(As(V)S4)2}(2-) for 1 and a cyclic thioarsenate anion (As(III)2S6)(2-) for 2. In 2, the [As(III)2(S2)2S2](2-) anion can be described as two (As(III)S3)(3-) trigonal-pyramids interlinked through S-S bonds. The method to obtain new metal complex cations shown here, introducing an anionic second ligand to modify the number of coordination sites and the charges of the metal complex cations simultaneously, is different from the traditional methods, varying either the TM center or the organic ligand or employing mixed neutral organic ligands, and may open up a new route for preparing novel chalcogenidometalates. Compounds 1 and 2 exhibit wide optical gaps of 2.20 and 2.67 eV, respectively, and photoluminescence with the emission maxima occurring around 440 nm. Magnetic measurements show the presence of antiferromagnetic interactions between Mn(II) centers in the two compounds.

Concentrations of metals in blood and feathers of nestling ospreys (Pandion haliaetus) in Chesapeake and Delaware Bays

USGS Publications Warehouse

Rattner, B.A.; Golden, N.H.; Toschik, P.C.; McGowan, P.C.; Custer, T.W.

2008-01-01

In 2000, 2001, and 2002, blood and feather samples were collected from 40-45-day-old nestling ospreys (Pandion haliaetus) from Chesapeake Bay and Delaware Bay and River. Concentrations of 18 metals, metalloids, and other elements were determined in these samples by inductively coupled plasma-mass spectroscopy, and Hg concentrations were measured by cold vapor atomic absorption spectroscopy. When compared to concurrent reference areas (South, West, and Rhode Rivers), mean As and Hg concentrations in blood were greater (p < 0.05) in two of three Chesapeake Bay regions of concern (Baltimore Harbor [As: 1.18 vs. 0.548 mug/g dw], Anacostia River [Hg: 0.305 vs. 0.178 mug/g dw], and Elizabeth River [As: 0.876 vs. 0.663 mug/g dw; Hg: 0.260 vs. 0.180 mug/g dw]). Lead was detected more frequently in blood of nestlings from the highly industrialized Elizabeth River compared to the rural reference area. When compared to the concurrent reference area, mean Al, Ba, Hg, Mn, and Pb concentrations in feathers were substantially greater (p < 0.05) in one or more Chesapeake regions of concern (Anacostia River [Al: 206 vs. 62.1 mug/g dw; Ba: 3.31 vs. 0.823 mug/g dw; Mn: 65.4 vs. 22.9 mug/g dw] and Elizabeth River [Al: 165 vs. 63.5 mug/g dw; Hg: 1.24 vs. 0.599 mug/g dw; Pb 1.47 vs. 0.543 mug/g dw]). When compared to the coastal Inland Bays reference area, feathers of nestlings from northern Delaware Bay and River had greater concentrations (p < 0.05) of Ba (1.90 vs. 0.660 mug/g dw), Fe (258 vs. 109 mug/g dw), Mn (18.5 vs. 4.66 mug/g dw), Mo (0.130 vs. 0.040 mug/g dw), Pb (1.96 vs. 0.624 mug/g dw), and V (0.671 vs. 0.325 mug/g dw), presumably due to extensive metal-working and petroleum refinery activities. Concentrations of Hg in nestling feathers from Delaware were frequently greater than in the Chesapeake. The present findings and those of related reproductive studies suggest that concentrations of several heavy metals (e.g., Cd, Hg, Pb) in nestling blood and feathers from Chesapeake

22 CFR 401.22 - Attendance of witnesses and production of documents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... documents. 401.22 Section 401.22 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.22 Attendance of witnesses and production of documents. (a... authorized by the Chairman of that section. (b) All applications for subpoena or other process to compel the...

The Standard Joint Unit.

PubMed

Casajuana Kögel, Cristina; Balcells-Olivero, María Mercedes; López-Pelayo, Hugo; Miquel, Laia; Teixidó, Lídia; Colom, Joan; Nutt, David John; Rehm, Jürgen; Gual, Antoni

2017-07-01

Reliable data on cannabis quantities is required to improve assessment of cannabis consumption for epidemiological analysis and clinical assessment, consequently a Standard Joint Unit (SJU) based on quantity of 9-Tetrahydrocannabinol (9-THC) has been established. Naturalistic study of a convenience sample recruited from February 2015-June 2016 in universities, leisure spaces, mental health services and cannabis clubs in Barcelona. Adults, reporting cannabis use in the last 60 days, without cognitive impairment or language barriers, answered a questionnaire on cannabis use and were asked to donate a joint to further determine their 9-THC and Cannabidiol (CBD) content. 492 participants donated 315 valid joints. Donators were on average 29 years old, mostly men (77%), single (75%), with at least secondary studies (73%) and in active employment (63%). Marijuana joints (N=232) contained a median of 6.56mg of 9-THC (Interquartile range-IQR=10,22) and 0.02mg of CBD (IQR=0.02); hashish joints (N=83) a median of 7.94mg of 9-THC (IQR=10,61) and 3.24mg of CBD (IQR=3.21). Participants rolled 4 joints per gram of cannabis and paid 5€ per gram (median values). Consistent 9-THC-content in joints lead to a SJU of 7mg of 9-THC, the integer number closest to the median values shared by both cannabis types. Independently if marijuana or hashish, 1 SJU = 1 joint = 0.25 g of cannabis = 7 mg of 9-THC. For CBD, only hashish SJU contained relevant levels. Similarly to the Standard Drink Unit for alcohol, the SJU is useful for clinical, epidemiological and research purposes. Copyright © 2017 Elsevier B.V. All rights reserved.

The Future of U.S. Sea Power

DTIC Science & Technology

1993-05-01

significant as changes which occurred a century ago with the Teddy Roosevelt-sponsored Mahanian revolution. Indeed, one critic 3 . hinks this "hurtful...crucial areas as well as jobs seem to be at play. He has endorsed development of the V-22 Osprey for the Marines and improvement in fast sealift...total) 450 340 290 Carriers 13 12 8 SSNs 80 40 40 Assault Ships 50 50 50 Marine Corps Active Divisions 21/3 2 2 Reserve Divisions 1 1 1 Sealift Fast

Organochlorine pesticides, PCBs, and mercury in Osprey (Pandion haliaetus) eggs from the Upper Volga River, Russia

USGS Publications Warehouse

Henny, Charles J.; Galushin, V.M.; Kuznetsov, A.V.; Meyburg, B.-U.; Chancellor, R.D.; Ferrero, J.J.

1998-01-01

The Osprey population associated with Darwin Nature Reserve and the Rybinsk Reservoir increased from only a few pairs prior to the creation of the reservoir in the late 1940s , to about 45-50 pairs in 1994. Productivity rates were excellent in 1988 and 1989 (1.38 young/occupied nest), but extremely low in 1987 (0.47 young/occupied nest). A chemical spill into the Volga River in early 1987 resulted in a massive fish kill, which was believed responsible for low production that year. With the exception of the year of the chemical spill and 1992 (the year an egg was collected from 10 of 11 nests studied), production was comparable to rates observed in stable or increasing populations in Byelorussia, Finland, and Sweden. The p.p'-DDE (DDE), polychlorinated biphenyl (PCB), and mercury concentrations from eggs collected in 1992 were below known effect levels and eggshell thickness showed only 6.3 % thinning - an amount not associated with reproductive problems.

The structure and properties of a nickel-base superalloy produced by osprey atomization-deposition

NASA Astrophysics Data System (ADS)

Bricknell, Rodger H.

1986-04-01

The production of a nickel-base superalloy, René* 80, by the Osprey atomization-deposition process has been investigated. Dense (>99 pct) material with a fine-grained equiaxed microstructure was deposited using either argon or nitrogen as the atomizing gas. Defects present in the material included a chill region at the collector plate interface, entrapped recirculated particles, porosity, and ceramic particles from the melting and dispensing system. In contrast to other rapid solidification techniques, low oxygen pick-ups are noted in the current technique. Tensile strengths above those displayed by castings are found in both nitrogen and argon atomized material, and in both the as-deposited and heat treated conditions. In addition, no profound mid-temperature ductility loss is displayed by this low oxygen material, in contrast to results on other rapidly solidified material with high oxygen contents. These results are explained in terms of oxygen embrittlement. In view of the excellent properties measured, the attractive economics of the process, and the fact that fine control of the gas/metal flow ratio is shown to be unnecessary, it is concluded that atomization-deposition presents an attractive potential production route for advanced alloys.

Neutron-deuteron analyzing power data at En=22.5 MeV

NASA Astrophysics Data System (ADS)

Weisel, G. J.; Tornow, W.; Crowell, A. S.; Esterline, J. H.; Hale, G. M.; Howell, C. R.; O'Malley, P. D.; Tompkins, J. R.; Witała, H.

2014-05-01

We present measurements of n-d analyzing power, Ay(θ), at En=22.5 MeV. The experiment uses a shielded neutron source which produced polarized neutrons via the 2H(d⃗,n⃗)3He reaction. It also uses a deuterated liquid-scintillator center detector and six pairs of liquid-scintillator neutron side detectors. Elastic neutron scattering events are identified by using time-of-flight techniques and by setting a window in the center detector pulse-height spectrum. The beam polarization is monitored by using a high-pressure helium gas cell and an additional pair of liquid-scintillator side detectors. The n-d Ay(θ) data were corrected for finite-geometry and multiple-scattering effects using a Monte Carlo simulation of the experiment. The 22.5-MeV data demonstrate that the three-nucleon analyzing power puzzle also exists at this energy. They show a significant discrepancy with predictions of high-precision nucleon-nucleon potentials alone or combined with Tucscon-Melbourne or Urbana IX three-nucleon forces, as well as currently available effective-field theory based potentials of next-to-next-to-next-to-leading order.

Assessment of biological effects of chlorinated hydrocarbons in osprey chicks

USGS Publications Warehouse

Elliott, J.E.; Wilson, L.K.; Henny, Charles J.; Trudeau, Suzanne F.; Leighton, Frederick A.; Kennedy, Sean W.; Cheng, Kimberly M.

2001-01-01

Osprey (Pandion haliaetus) eggs were collected during 1995 and 1996 at seven sites along the Fraser and Columbia River systems of British Columbia, Canada, and Washington and Oregon, USA. Fifty-four eggs were placed into a laboratory incubator. Thirty-eight of the hatched chicks were sacrificed within 24 h. Hatching success did not differ among sites and therefore between treatment and reference areas. Residual yolk sacs of eggs collected downstream of the large bleached-kraft pulp mill at Castlegar contained greater mean concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, 2,930 ng/kg lipid) compared with reference sites such as the Nechako River, an upper tributary of the Fraser system (33.7 ng/kg). Total polychlorinated biphenyls (PCBs) in yolk sacs were also higher at Castlegar and in samples from the Columbia River downstream of Portland, Oregon, compared with those from the Nechako River. Concentrations of measured chemicals, including TCDD toxic equivalents (TEQs), total PCBs, p,pa??-dichlorodiphenylethylene (p,pa??-DDE), and other organochlorines were not different in eggs that failed to hatch compared with calculated whole-egg values for hatched eggs. There were significant biochemical responses; a hepatic cytochrome P4501A (CYP1A) cross-reactive protein was detected in all samples tested and correlated positively with ethoxyresorufin o-deethylase (EROD) activity and yolk sac concentrations of TEQs and total PCBs. Tissue concentrations of vitamin A compounds varied among sites and correlated positively with yolk sac concentrations of TEQs and PCBs. Morphological, histological, and other physiological parameters, including chick growth, edema, deformities, and hepatic and renal porphyrin concentrations, neither varied among sites nor showed concentration-related effects.

Clostridium perfringens enterotoxin is a superantigen reactive with human T cell receptors V beta 6.9 and V beta 22

PubMed Central

1992-01-01

Candidate superantigens were screened for their ability to induce lysis of human histocompatibility leukocyte antigen class II-positive targets by human CD8+ influenza-specific cytotoxic T cell (CTL) lines. Clostridium perfringens enterotoxin (CPET) induced major histocompatibility complex unrestricted killing by some but not all CTL lines. Using "anchored" polymerase chain reactions, CPET was shown to selectively stimulate peripheral blood lymphocytes bearing T cell receptor V beta 6.9 and V beta 22 in five healthy donors. V beta 24, V beta 21, V beta 18, V beta 5, and V beta 6.1-5 appeared to be weakly stimulated. Antigen processing was not required for CPET to induce proliferation. Like the staphylococcal enterotoxins, CPET is a major cause of food poisoning. These data suggest that superantigenic and enterotoxigenic properties may be closely linked. PMID:1512551

Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons

PubMed Central

López Soto, Eduardo Javier; Agosti, Francina; Cabral, Agustina; Mustafa, Emilio Roman; Damonte, Valentina Martínez; Gandini, Maria Alejandra; Rodríguez, Silvia; Castrogiovanni, Daniel; Felix, Ricardo; Perelló, Mario

2015-01-01

The growth hormone secretagogue receptor type 1a (GHSR1a) has the highest known constitutive activity of any G protein–coupled receptor (GPCR). GHSR1a mediates the action of the hormone ghrelin, and its activation increases transcriptional and electrical activity in hypothalamic neurons. Although GHSR1a is present at GABAergic presynaptic terminals, its effect on neurotransmitter release remains unclear. The activities of the voltage-gated calcium channels, CaV2.1 and CaV2.2, which mediate neurotransmitter release at presynaptic terminals, are modulated by many GPCRs. Here, we show that both constitutive and agonist-dependent GHSR1a activity elicit a strong impairment of CaV2.1 and CaV2.2 currents in rat and mouse hypothalamic neurons and in a heterologous expression system. Constitutive GHSR1a activity reduces CaV2 currents by a Gi/o-dependent mechanism that involves persistent reduction in channel density at the plasma membrane, whereas ghrelin-dependent GHSR1a inhibition is reversible and involves altered CaV2 gating via a Gq-dependent pathway. Thus, GHSR1a differentially inhibits CaV2 channels by Gi/o or Gq protein pathways depending on its mode of activation. Moreover, we present evidence suggesting that GHSR1a-mediated inhibition of CaV2 attenuates GABA release in hypothalamic neurons, a mechanism that could contribute to neuronal activation through the disinhibition of postsynaptic neurons. PMID:26283199

Selection of optimal welding condition for GTA pulse welding in root-pass of V-groove butt joint

NASA Astrophysics Data System (ADS)

Yun, Seok-Chul; Kim, Jae-Woong

2010-12-01

In the manufacture of high-quality welds or pipeline, a full-penetration weld has to be made along the weld joint. Therefore, root-pass welding is very important, and its conditions have to be selected carefully. In this study, an experimental method for the selection of optimal welding conditions is proposed for gas tungsten arc (GTA) pulse welding in the root pass which is done along the V-grooved butt-weld joint. This method uses response surface analysis in which the width and height of back bead are chosen as quality variables of the weld. The overall desirability function, which is the combined desirability function for the two quality variables, is used as the objective function to obtain the optimal welding conditions. In our experiments, the target values of back bead width and height are 4 mm and zero, respectively, for a V-grooved butt-weld joint of a 7-mm-thick steel plate. The optimal welding conditions could determine the back bead profile (bead width and height) as 4.012 mm and 0.02 mm. From a series of welding tests, it was revealed that a uniform and full-penetration weld bead can be obtained by adopting the optimal welding conditions determined according to the proposed method.

PIP₂ hydrolysis is responsible for voltage independent inhibition of CaV2.2 channels in sympathetic neurons.

PubMed

Vivas, Oscar; Castro, Hector; Arenas, Isabel; Elías-Viñas, David; García, David E

2013-03-08

GPCRs regulate Ca(V)2.2 channels through both voltage dependent and independent inhibition pathways. The aim of the present work was to assess the phosphatidylinositol-4,5-bisphosphate (PIP2) as the molecule underlying the voltage independent inhibition of Ca(V)2.2 channels in SCG neurons. We used a double pulse protocol to study the voltage independent inhibition and changed the PIP(2) concentration by means of blocking the enzyme PLC, filling the cell with a PIP(2) analogue and preventing the PIP(2) resynthesis with wortmannin. We found that voltage independent inhibition requires the activation of PLC and can be hampered by internal dialysis of exogenous PIP(2). In addition, the recovery from voltage independent inhibition is blocked by inhibition of the enzymes involved in the resynthesis of PIP(2). These results support that the hydrolysis of PIP(2) is responsible for the voltage independent inhibition of Ca(V)2.2 channels. Copyright © 2013 Elsevier Inc. All rights reserved.

Effects of the Heterogeneity in the Electron Beam Welded Joint on Mechanical Properties of Ti6Al4V Alloy

NASA Astrophysics Data System (ADS)

Liu, Jing; Gao, Xiao-Long; Zhang, Lin-Jie; Zhang, Jian-Xun

2015-01-01

The aim of this investigation was to evaluate the effect of microstructure heterogeneity on the tensile and low cycle fatigue properties of electron beam welded (EBW) Ti6Al4V sheets. To achieve this goal, the tensile and low cycle fatigue property in the EBW joints and base metal (BM) specimens is compared. During the tensile testing, digital image correlation technology was used to measure the plastic strain field evolution within the specimens. The experimental results showed that the tensile ductility and low cycle fatigue strength of EBW joints are lower than that of BM specimens, mainly because of the effect of microstructure heterogeneity of the welded joint. Moreover, the EBW joints exhibit the cyclic hardening behavior during low fatigue process, while BM specimens exhibit the cyclic softening behavior. Compared with the BM specimens with uniform microstructure, the heterogeneity of microstructure in the EBW joint is found to decrease the mechanical properties of welded joint.

Degenerative joint disease: multiple joint involvement in young and mature dogs.

PubMed

Olsewski, J M; Lust, G; Rendano, V T; Summers, B A

1983-07-01

Radiologic, pathologic, and ancillary methods were used to determine the occurrence of degenerative joint disease involving multiple joints of immature and adult dogs. Animals were selected for the development of hip joint dysplasia and chronic degenerative joint disease. Of disease-prone dogs, 82% (45 of 55 dogs) had radiologic changes, indicative of hip dysplasia, by 1 year of age. At necropsy, more abnormal joints were identified than by radiographic examination. Among 92 dogs between 3 to 11 months of age that had joint abnormalities, 71% had hip joint involvement; 38%, shoulder joint involvement; 22%, stifle joint involvement; and 40% had multiple joint involvement. Polyarthritis was asymptomatic and unexpected. Radiographic examination of older dogs also revealed evidence of degenerative joint disease in many joints. Multiple joint involvement was substantiated at necropsy of young and mature dogs. A similar pattern of polyarticular osteoarthritis was revealed in a survey (computer search) of necropsy reports from medical case records of 100 adult and elderly dogs. Usually, the joint disease was an incidental observation, unrelated to the clinical disease or to the cause of death. The frequent occurrence of degenerative changes in several joints of dogs aged 6 months to 17 years indicated that osteoarthritis may be progressive in these joints and raises the possibility that systemic factors are involved in the disease process.

Site preference of alloying elements in DO22-Ni3V phase: Phase-field and first-principles study

NASA Astrophysics Data System (ADS)

Zhang, Ding-Ni; Shangguan, Qian-Qian; Liu, Fu; Zhang, Ming-Yi

2015-07-01

Site preference of alloying elements in DO22-Ni3V phase was investigated using phase-field and first-principles method. The concentrations of alloying elements on sublattices of DO22-Ni3V phase were quantitatively studied using phase-field model based on microscopic diffusion equations. The phase-field computation results demonstrate that the concentration differences of alloying elements on the NiI and NiII site are attributed to the coordination environment difference. Host atoms Ni and substitutional ternary additions Al prefer to occupy NiI site. Antisite atoms V show site preference on the NiII site. Further reason of site preference of alloying elements on the two different Ni sites were studied using first-principles method to calculate the electronic structure of DO22-Ni3V phase. Calculation of density of states, orbitals population and charge population of the optimized Ni3V structure found that the electronic structures of NiI and NiII sites are different. Electronic structure difference, which is caused by coordination environment difference, is the essential reason for site selectivity behaviors of alloying elements on NiI and NiII sites.

22 CFR 401.2 - Chairmen.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Chairmen. 401.2 Section 401.2 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.2 Chairmen. (a) The... be known as the Chairman of the United States Section of the International Joint Commission, and he...

Bone alterations are associated with ankle osteoarthritis joint pain

PubMed Central

Nakamura, Yukio; Uchiyama, Shigeharu; Kamimura, Mikio; Komatsu, Masatoshi; Ikegami, Shota; Kato, Hiroyuki

2016-01-01

The etiology of ankle osteoarthritis (OA) is largely unknown. We analyzed 24 ankle OA of 21 patients diagnosed by plain radiographs using magnetic resonance imaging (MRI). Ankle joint pain disappeared in 22 out of 24 joints by conservative treatment. MRI bone signal changes in and around the ankle joints were observed in 22 of 24 joints. Bone signal changes along the joint line were seen in 10 of 11 joints as a Kellgren-Lawrence (KL) grade of II to IV. Such signal changes were witnessed in only 4 of 13 joints with KL grade 0 or I. In the talocrural joint, bone alterations occurred in both tibia and talus bones through the joint line in cases of KL grade III or IV, while focal bone alterations were present in the talus only in KL grade I or II cases. Sixteen of 24 joints exhibited intraosseous bone signal changes, which tended to correspond to joint pain of any ankle OA stage. Our results suggest that bone alterations around the ankle joint might be one of the etiologies of OA and associated with ankle joint pain. PMID:26776564

Bone alterations are associated with ankle osteoarthritis joint pain.

PubMed

Nakamura, Yukio; Uchiyama, Shigeharu; Kamimura, Mikio; Komatsu, Masatoshi; Ikegami, Shota; Kato, Hiroyuki

2016-01-18

The etiology of ankle osteoarthritis (OA) is largely unknown. We analyzed 24 ankle OA of 21 patients diagnosed by plain radiographs using magnetic resonance imaging (MRI). Ankle joint pain disappeared in 22 out of 24 joints by conservative treatment. MRI bone signal changes in and around the ankle joints were observed in 22 of 24 joints. Bone signal changes along the joint line were seen in 10 of 11 joints as a Kellgren-Lawrence (KL) grade of II to IV. Such signal changes were witnessed in only 4 of 13 joints with KL grade 0 or I. In the talocrural joint, bone alterations occurred in both tibia and talus bones through the joint line in cases of KL grade III or IV, while focal bone alterations were present in the talus only in KL grade I or II cases. Sixteen of 24 joints exhibited intraosseous bone signal changes, which tended to correspond to joint pain of any ankle OA stage. Our results suggest that bone alterations around the ankle joint might be one of the etiologies of OA and associated with ankle joint pain.

Sacroiliac joint dysfunction.

PubMed

Ilaslan, Hakan; Arslan, Ahmet; Koç, Omer Nadir; Dalkiliç, Turker; Naderi, Sait

2010-07-01

Sacroiliac joint dysfunction is a disorder presenting with low back and groin pain. It should be taken into consideration during the preoperative differential diagnosis of lumbar disc herniation, lumbar spinal stenosis and facet syndrome. Four cases with sacroiliac dysfunction are presented. The clinical and radiological signs supported the evidence of sacroiliac dysfunction, and exact diagnosis was made after positive response to sacroiliac joint block. A percutaneous sacroiliac fixation provided pain relief in all cases. The mean VAS scores reduced from 8.2 to 2.2. It is concluded that sacroiliac joint dysfunction diagnosis requires a careful physical examination of the sacroiliac joints in all cases with low back and groin pain. The diagnosis is made based on positive response to the sacroiliac block. Sacroiliac fixation was found to be effective in carefully selected cases.

Surgical treatment of acute type V acromioclavicular joint dislocations in professional athletes: an anatomic ligament reconstruction with synthetic implant augmentation.

PubMed

Triantafyllopoulos, Ioannis K; Lampropoulou-Adamidou, Kalliopi; Schizas, Nikitas P; Karadimas, Eleftherios V

2017-12-01

Most acromioclavicular (AC) joint injuries occur in men in their third decade of life during high-speed or high-impact body contact sports. The management of acute complete AC joint dislocation is surgical. Current surgical techniques include anatomic reconstruction of the main restraints of the AC joint and aim to improve functional outcomes and to reduce the complication rate. We present 10 cases of acute type V AC joint dislocation in professional athletes treated surgically with anatomic reconstruction of the coracoclavicular and AC ligaments and augmentation with the use of a synthetic polyester tape. The minimum follow-up of the patients was 2 years (mean, 48 months; range, 24-86 months). The postoperative functional outcome was assessed at 1 year and 2 years using the Constant-Murley, American Shoulder and Elbow Surgeons, and modified University of California-Los Angeles scoring systems. In all cases, the postoperative scores were significantly improved (P < .005 in all comparisons with the preoperative scores), and all patients returned to their preinjury high level of activity 6 months postoperatively. Radiographs at 1 month and 6 months revealed the maintenance of reduction. There were no complications. According to the results of our series of patients, demanding cases of acute AC joint dislocation Rockwood type V, in professional athletes, require anatomic fixation of both coracoclavicular and AC ligaments for return to sports as soon as possible and at the preinjury level of performance. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Mean-time-to-failure study of flip chip solder joints on Cu/Ni(V)/Al thin-film under-bump-metallization

NASA Astrophysics Data System (ADS)

Choi, W. J.; Yeh, E. C. C.; Tu, K. N.

2003-11-01

Electromigration of eutectic SnPb flip chip solder joints and their mean-time-to-failure (MTTF) have been studied in the temperature range of 100 to 140 °C with current densities of 1.9 to 2.75×104 A/cm2. In these joints, the under-bump-metallization (UBM) on the chip side is a multilayer thin film of Al/Ni(V)/Cu, and the metallic bond-pad on the substrate side is a very thick, electroless Ni layer covered with 30 nm of Au. When stressed at the higher current densities, the MTTF was found to decrease much faster than what is expected from the published Black's equation. The failure occurred by interfacial void propagation at the cathode side, and it is due to current crowding near the contact interface between the solder bump and the thin-film UBM. The current crowding is confirmed by a simulation of current distribution in the solder joint. Besides the interfacial void formation, the intermetallic compounds formed on the UBM as well as the Ni(V) film in the UBM have been found to dissolve completely into the solder bump during electromigration. Therefore, the electromigation failure is a combination of the interfacial void formation and the loss of UBM. Similar findings in eutectic SnAgCu flip chip solder joints have also been obtained and compared.

Site characterization at Groningen gas field area through joint surface-borehole H/V analysis

NASA Astrophysics Data System (ADS)

Spica, Zack J.; Perton, Mathieu; Nakata, Nori; Liu, Xin; Beroza, Gregory C.

2018-01-01

A new interpretation of the horizontal to vertical (H/V) spectral ratio in terms of the Diffuse Field Assumption (DFA) has fuelled a resurgence of interest in that approach. The DFA links H/V measurements to Green's function retrieval through autocorrelation of the ambient seismic field. This naturally allows for estimation of layered velocity structure. In this contribution, we further explore the potential of H/V analysis. Our study is facilitated by a distributed array of surface and co-located borehole stations deployed at multiple depths, and by detailed prior information on velocity structure that is available due to development of the Groningen gas field. We use the vertical distribution of H/V spectra recorded at discrete depths inside boreholes to obtain shear wave velocity models of the shallow subsurface. We combine both joint H/V inversion and borehole interferometry to reduce the non-uniqueness of the problem and to allow faster convergence towards a reliable velocity model. The good agreement between our results and velocity models from an independent study validates the methodology, demonstrates the power of the method, but more importantly provides further constraints on the shallow velocity structure, which is an essential component of integrated hazard assessment in the area.

Multi-Body Analysis of the 1/5 Scale Wind Tunnel Model of the V-22 Tiltrotor

NASA Technical Reports Server (NTRS)

Ghiringhelli, G. L.; Masarati, P.; Mantegazza, P.; Nixon, M. W.

1999-01-01

The paper presents a multi-body analysis of the 1/5 scale wind tunnel model of the V-22 tiltrotor, the Wing and Rotor Aeroelastic Testing System (WRATS), currently tested at NASA Langley Research Center. An original multi-body formulation has been developed at the Dipartimento di Ingegneria Aerospaziale of the Politecnico di Milano, Italy. It is based on the direct writing of the equilibrium equations of independent rigid bodies, connected by kinematic constraints that result in the addition of algebraic constraint equations, and by dynamic constraints, that directly contribute to the equilibrium equations. The formulation has been extended to the simultaneous solution of interdisciplinary problems by modeling electric and hydraulic networks, for aeroservoelastic problems. The code has been tailored to the modeling of rotorcrafts while preserving a complete generality. A family of aerodynamic elements has been introduced to model high aspect aerodynamic surfaces, based on the strip theory, with quasi-steady aerodynamic coefficients, compressibility, post-stall interpolation of experimental data, dynamic stall modeling, and radial flow drag. Different models for the induced velocity of the rotor can be used, from uniform velocity to dynamic in flow. A complete dynamic and aeroelastic analysis of the model of the V-22 tiltrotor has been performed, to assess the validity of the formulation and to exploit the unique features of multi-body analysis with respect to conventional comprehensive rotorcraft codes; These are the ability to model the exact kinematics of mechanical systems, and the possibility to simulate unusual maneuvers and unusual flight conditions, that are particular to the tiltrotor, e.g. the conversion maneuver. A complete modal validation of the analytical model has been performed, to assess the ability to reproduce the correct dynamics of the system with a relatively coarse beam model of the semispan wing, pylon and rotor. Particular care has been used

Effects of 22 MeV protons on single junction and silicon controlled rectifiers

NASA Technical Reports Server (NTRS)

Beatty, M. E., III

1972-01-01

The effects of 22-MeV protons on various types of silicon single junction and silicon controlled rectifiers were investigated. The results show that low-leakage devices and silicon controlled rectifiers are the most susceptable to radiation damage. There are also differences noted between single junction rectifiers of the same type made by different manufacturers, which emphasizes the need for better selection of devices used in spacecraft.

Virtual Beach v2.2 User Guide

EPA Science Inventory

Virtual Beach version 2.2 (VB 2.2) is a decision support tool. It is designed to construct site-specific Multi-Linear Regression (MLR) models to predict pathogen indicator levels (or fecal indicator bacteria, FIB) at recreational beaches. MLR analysis has outperformed persisten...

Effect of welding speed on butt joint quality of Ti-6Al-4V alloy welded using a high-power Nd:YAG laser

NASA Astrophysics Data System (ADS)

Cao, X.; Jahazi, M.

2009-11-01

Annealed Ti-6Al-4V alloy sheets with 1 and 2 mm thickness are welded using a 4 kW Nd:YAG laser system. The effects of welding speed on surface morphology and shape, welding defects, microstructure, hardness and tensile properties are investigated. Weld joints without or with minor cracks, porosity and shape defects were obtained indicating that high-power Nd:YAG laser welding is a suitable method for Ti-6Al-4V alloy. The fusion zone consists mainly of acicular α' martensite leading to an increase of approximately 20% in hardness compared with that in the base metal. The heat-affected zone consists of a mixture of α' martensite and primary α phases. Significant gradients of microstructures and hardness are obtained over the narrow heat-affected zone. The laser welded joints have similar or slightly higher joint strength but there is a significant decrease in ductility. The loss of ductility is related to the presence of micropores and aluminum oxide inclusions.

22 CFR 401.4 - Duties of secretaries.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Duties of secretaries. 401.4 Section 401.4 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.4 Duties of secretaries. (a) The secretaries shall act as joint secretaries at all meetings and...

Effects of elastic strain energy on the antisite defect of D0 22-Ni 3V phase

NASA Astrophysics Data System (ADS)

Zhang, Jing; Chen, Zheng; Wang, Yong Xin; Lu, Yan Li

2010-01-01

A time-dependent phase field microelasticity model of an elastically anisotropic Ni-Al-V solid is employed for a D0 22-Ni 3V antisite defect application. The elastic strain energy (ESE), caused by a coherent misfit, changes the behavior of the temporal evolution occupancy probability (OP), slows down the phase transformation, and eventually leads to directional coarsening of coherent microstructures. In particular, for the antisite defects (Ni V, V Ni) and ternary alloying elements (Al Ni, Al V), ESE is responsible for the decrease in the calculated equilibrium values of Ni V, Al Ni, and Al V, as well as the increase in the equilibrium value of V Ni. The gap between Ni V and V Ni and Al Ni and Al V is narrowed in the system involving ESE, but the calculated equilibrium magnitude of Ni V is still greater than that of V Ni. The calculated equilibrium magnitude of Al Ni was always greater than Al V in this study.

Interfacial reaction of intermetallic compounds of ultrasonic-assisted brazed joints between dissimilar alloys of Ti6Al4V and Al4Cu1Mg.

PubMed

Ma, Zhipeng; Zhao, Weiwei; Yan, Jiuchun; Li, Dacheng

2011-09-01

Ultrasonic-assisted brazing of Al4Cu1Mg and Ti6Al4V using Zn-based filler metal (without and with Si) has been investigated. Before brazing, the Ti6Al4V samples were pre-treated by hot-dip aluminizing and ultrasonic dipping in a molten filler metal bath in order to control the formation of intermetallic compounds between the Ti6Al4V samples and the filler metal. The results show that the TiAl(3) phase was formed in the interface between the Ti6Al4V substrate and the aluminized coating. For the Zn-based filler metal without Si, the Ti6Al4V interfacial area of the brazed joint did not change under the effect of the ultrasonic wave, and only consisted of the TiAl(3) phase. For the Zn-based filler metal with Si, the TiAl(3) phase disappeared and a Ti(7)Al(5)Si(12) phase was formed at the interfacial area of the brazed joints under the effect of the ultrasonic wave. Due to the TiAl(3) phase completely changing to a Ti(7)Al(5)Si(12) phase, the morphology of the intermetallic compounds changed from a block-like shape into a lamellar-like structure. The highest shear strength of 138MPa was obtained from the brazed joint free of the block-like TiAl(3) phase. Copyright © 2011 Elsevier B.V. All rights reserved.

Angular momentum dependence in 22 MeV $alpha$-particle elastic scattering by light nuclei

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lega, J.; Macq, P.C.

1974-01-01

Elastic scattering of 22 MeV alpha -particles by /sup 23, /sup 24,15,26/ Mg, /sup 27/Al and /sup 28/Si was measured between 24 and 174 deg lab. Partial angular distributions, from 120 to 174 deg , were also measured at incident energies of 18.4 and 20.7 MeV for /sup 24/Mg, and 18.9 and 20.5 MeV for /sup 28/ Si. The most striking feature of the data is the large-angle behavior spin-zero nuclei display more pronounced backward oscillations and the cross section rises more steeply towards 180 deg for 4n nuclei than for the others. Optical Model analyses with an l-dependent absorptionmore » and a minimum of free parameters are used to describe the general trend of the data for A = 23 to 28 nuclei at different energies; a spinorbit coupling term, 2.75 MeV deep, is added to describe the /sup 23/Na scattering data. (auth)« less

Effect of micromorphology at the fatigue crack tip on the crack growth in electron beam welded Ti-6Al-4V joint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tao, Junhui; Hu, Shubing, E-mail: 187352581@qq.com

In this paper, we describe experiments on welded joints of Ti-6Al-4V alloy specimens exhibiting fatigue characteristics in the base metal (BM), hot affected zone (HAZ) and fuse zone (FZ). The effect of micromorphology on crack propagation at the tip of the fatigue crack in joints formed by electron beam welding was investigated using an optical microscope, transmission electron microscope and other methodologies. The results demonstrated that the fatigue crack originated in and propagated along α/β boundaries in the BM. In the HAZ, the fatigue crack occurred at the boundary between martensite laths, and propagated through most irregular-equiaxed α phases andmore » a few martensite laths. In the FZ, the fatigue crack originated at the boundaries between the fine crushing phases among martensite laths, and propagated along a majority of α/β boundaries and several narrow martensite laths. The electron beam welded joint of Ti-6Al-4V alloy showed instances of zigzag fatigue cracks that increased in degree from lowest in the HAZ, moderate in the FZ to greatest in the BM. Conversely, fatigue crack growth rate (FCGR) was greatest in the HAZ, less in the FZ and slowest in the BM. - Highlights: •Ti-6Al-4V welded joint exhibits different fatigue characteristics. •The fatigue crack propagates along α/β boundaries in the BM. •The fatigue crack propagates through α phases and martensite laths in the HAZ. •The fatigue crack propagates along α/β boundaries and martensite laths in the FZ. •Fatigue crack growth rate is fastest in the HAZ, less in the FZ, slowest in the BM.« less

Nucleon and deuteron scattering cross sections from 25 MV/Nucleon to 22.5 GeV/Nucleon

NASA Technical Reports Server (NTRS)

Townsend, L. W.; Wilson, J. W.; Bidasaria, H. B.

1983-01-01

Within the context of a double-folding optical potential approximation to the exact nucleus-nucleus multiple-scattering series, eikonal scattering theory is used to generate tables of nucleon and deuteron total and absorption cross sections at kinetic energies between 25 MeV/nucleon and 22.5 GeV/nucleon for use in cosmic-ray transport and shielding studies. Comparisons of predictions for nucleon-nucleus and deuteron-nucleus absorption and total cross sections with experimental data are also made.

7 CFR 46.22 - Accounting for dumped produce.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Accounting for dumped produce. 46.22 Section 46.22... Market Receivers § 46.22 Accounting for dumped produce. A clear and complete record shall be maintained... justifying dumping shall be forwarded to the consignor or joint account partner with the accounting and a...

Lymphatic involution and early mortality in the young chicken produced by 2.2 GeV protons

NASA Technical Reports Server (NTRS)

Montour, J. L.; Shellabarger, C. J.

1972-01-01

Young single-comb white Leghorn cockerels were subjected to single acute doses of either 2.2 GeV protons or 250 kVp X-rays. Since young chickens exposed in the lethal range die within 48 hours of exposure, an hourly tabulation of deaths was recorded for this length of time after exposure. Animals which were exposed to sublethal doses were killed five days after exposure and their major lymphatic organs, (thymus, bursa, and spleen), removed and weighed. In the lethal range, animals exposed to 2.2 GeV protons died sooner than those receiving similar doses of X-rays, but total mortality was similar in each case at similar dose levels. The 48 hour LD sub 50 was determined to be 710 rad. Measured five days after exposure, 50% depression ED sub 50 for lymphatic organs occurred as follows: (1) thymus, 350 rad; (2) pursa, 500 rad, and (3) spleen, 450 rad. In all case R.B.E. values were not different from unity.

Voltage-independent inhibition of Ca(V)2.2 channels is delimited to a specific region of the membrane potential in rat SCG neurons.

PubMed

Vivas, Oscar; Arenas, Isabel; García, David E

2012-06-01

Neurotransmitters and hormones regulate Ca(V)2.2 channels through a voltage-independent pathway which is not well understood. It has been suggested that this voltage-independent inhibition is constant at all membrane voltages. However, changes in the percent of voltage-independent inhibition of Ca(V)2.2 have not been tested within a physiological voltage range. Here, we used a double-pulse protocol to isolate the voltage-independent inhibition of Ca(V)2.2 channels induced by noradrenaline in rat superior cervical ganglion neurons. To assess changes in the percent of the voltage-independent inhibition, the activation voltage of the channels was tested between -40 and +40 mV. We found that the percent of voltage-independent inhibition induced by noradrenaline changed with the activation voltage used. In addition, voltage-independent inhibition induced by oxo-M, a muscarinic agonist, exhibited the same dependence on activation voltage, which supports that this pattern is not exclusive for adrenergic activation. Our results suggested that voltage-independent inhibition of Ca(V)2.2 channels depends on the activation voltage of the channel in a physiological voltage range. This may have relevant implications in the understanding of the mechanism involved in voltage-independent inhibition.

Flexor bias of joint position in humans during spaceflight

NASA Technical Reports Server (NTRS)

McCall, G. E.; Goulet, C.; Boorman, G. I.; Roy, R. R.; Edgerton, V. R.

2003-01-01

The ability to estimate ankle and elbow joint position was tested before, during, and after a 17-day spaceflight. Subjects estimated targeted joint angles during isovelocity (IsoV) joint movements with agonist muscle groups either active or relaxed. These movements included elbow extension (EE) and elbow flexion (EF), and plantarflexion (PF) and dorsiflexion (DF) of the ankle. Subjects also estimated these joint positions while moving the dynamometer at their chosen (variable) velocity (VarV) during EE and PF. For IsoV tests, no differences were observed between active and passive movements for either the ankle or elbow. Compared with those of pre-flight test days, estimates of targeted elbow joint angles were approximately 5 degrees to 15 degrees more flexed in-flight, and returned toward the pre-flight values during recovery. The spaceflight effects for the ankle were inconsistent and less prevalent than those for the elbow. The VarV PF test condition for the 120 degrees target angle at the ankle exhibited approximately 5 degrees to 7 degrees more DF target angle estimates in-flight compared with those pre- or post-flight. In contrast, during IsoV PF there was a tendency for ankle estimates to be approximately 2 degrees to 3 degrees more PF after 2-3 days exposure to spaceflight. These data indicate that during spaceflight the perception of elbow extension is greater than actuality, and are consistent with the interpretation that microgravity induced a flexor bias in the estimation of the actual elbow joint position. Moreover, these effects in joint proprioception during spaceflight were observed in individual isolated single-joint movements during tasks in which vestibular function in maintaining posture were minimal.

Flexor bias of joint position in humans during spaceflight.

PubMed

McCall, G E; Goulet, C; Boorman, G I; Roy, R R; Edgerton, V R

2003-09-01

The ability to estimate ankle and elbow joint position was tested before, during, and after a 17-day spaceflight. Subjects estimated targeted joint angles during isovelocity (IsoV) joint movements with agonist muscle groups either active or relaxed. These movements included elbow extension (EE) and elbow flexion (EF), and plantarflexion (PF) and dorsiflexion (DF) of the ankle. Subjects also estimated these joint positions while moving the dynamometer at their chosen (variable) velocity (VarV) during EE and PF. For IsoV tests, no differences were observed between active and passive movements for either the ankle or elbow. Compared with those of pre-flight test days, estimates of targeted elbow joint angles were approximately 5 degrees to 15 degrees more flexed in-flight, and returned toward the pre-flight values during recovery. The spaceflight effects for the ankle were inconsistent and less prevalent than those for the elbow. The VarV PF test condition for the 120 degrees target angle at the ankle exhibited approximately 5 degrees to 7 degrees more DF target angle estimates in-flight compared with those pre- or post-flight. In contrast, during IsoV PF there was a tendency for ankle estimates to be approximately 2 degrees to 3 degrees more PF after 2-3 days exposure to spaceflight. These data indicate that during spaceflight the perception of elbow extension is greater than actuality, and are consistent with the interpretation that microgravity induced a flexor bias in the estimation of the actual elbow joint position. Moreover, these effects in joint proprioception during spaceflight were observed in individual isolated single-joint movements during tasks in which vestibular function in maintaining posture were minimal.

The stargazin-related protein γ7 interacts with the mRNA binding protein hnRNP A2 and regulates the stability of specific mRNAs including CaV2.2

PubMed Central

Ferron, Laurent; Davies, Anthony; Page, Karen M.; Cox, David J.; Leroy, Jerôme; Waithe, Dominic; Butcher, Adrian J.; Sellaturay, Priya; Bolsover, Steven; Pratt, Wendy S.; Moss, Fraser J.; Dolphin, Annette C.

2009-01-01

The role(s) of the novel stargazin-like γ-subunit proteins remain controversial. We have shown previously that the neuron-specific γ7 suppresses the expression of certain calcium channels, particularly CaV2.2, and is therefore unlikely to operate as a calcium channel subunit. We now show that the effect of γ7 on CaV2.2 expression is via an increase in the degradation rate of CaV2.2 mRNA, and hence a reduction of CaV2.2 protein level. Furthermore, exogenous expression of γ7 in PC12 cells also decreased the endogenous CaV2.2 mRNA level. Conversely, knockdown of endogenous γ7 with short-hairpin RNAs produced a reciprocal enhancement of CaV2.2 mRNA stability and an increase in endogenous calcium currents in PC12 cells. Moreover, both endogenous and expressed γ7 are present on intracellular membranes, rather than the plasma membrane. The cytoplasmic C-terminus of γ7 is essential for all its effects, and we show that γ7 binds directly via its C-terminus to a ribonucleoprotein (hnRNP A2), which also binds to a motif in CaV2.2 mRNA, and is associated with native CaV2.2 mRNA in PC12 cells. The expression of hnRNP A2 enhances CaV2.2 IBa and this enhancement is prevented by a concentration of γ7 that alone has no effect on IBa. The effect of γ7 is selective for certain mRNAs as it had no effect on α2δ-2 mRNA stability, but it decreased the mRNA stability for the potassium-chloride co-transporter, KCC1, which contains a similar hnRNP A2 binding motif to that in CaV2.2 mRNA. Our results indicate that γ7 plays a role in stabilizing CaV2.2 mRNA. PMID:18923037

Late effects of 2.2 GeV protons on the central nervous system.

NASA Technical Reports Server (NTRS)

Lippincott, S. W.; Calvo, W.

1971-01-01

Investigation of late pathological effects of high-energy (2.2 GeV) protons on the brain of rabbits, in a postirradiation period of up to 16 months following exposure at fluxes of 30, 100, and 1000 billion protons per sq cm. At the latter two irradiation-intensity levels, the kinds of brain lesions inflicted include large venous dilatation, thickening of vessel walls with deposit of amorphous PAS positive substance, thrombosis, perivascular infiltration of leukocytes and macrophages, mobilization of microglia cells, gliosis, demyelinization, and multiple small pseudocyst formation.

A vectorization of the Jameson-Caughey NYU transonic swept-wing computer program FLO-22-V1 for the STAR-100 computer

NASA Technical Reports Server (NTRS)

Smith, R. E.; Pitts, J. I.; Lambiotte, J. J., Jr.

1978-01-01

The computer program FLO-22 for analyzing inviscid transonic flow past 3-D swept-wing configurations was modified to use vector operations and run on the STAR-100 computer. The vectorized version described herein was called FLO-22-V1. Vector operations were incorporated into Successive Line Over-Relaxation in the transformed horizontal direction. Vector relational operations and control vectors were used to implement upwind differencing at supersonic points. A high speed of computation and extended grid domain were characteristics of FLO-22-V1. The new program was not the optimal vectorization of Successive Line Over-Relaxation applied to transonic flow; however, it proved that vector operations can readily be implemented to increase the computation rate of the algorithm.

Measurement of the strengths of the resonances at 417, 458, 611, 632 and 1222 keV in the 22Ne(p, γ)23Na reaction

NASA Astrophysics Data System (ADS)

Ferraro, Federico

2018-01-01

The 22Ne(p, γ)23Na reaction is part of the NeNa cycle of hydrogen burning. This cycle plays a key role in the nucleosynthesis of the elements between 20Ne and 27Al in red giant stars, asymptotic giant stars and classical nova explosions. The strengths of the resonances at proton energies above 400 keV are still affected by high uncertainty. In order to reduce this uncertainty, a precision study of some of the most intense resonances between 400 keV and 1250 keV has been performed at the HZDR 3 MV Tandetron. The target, made of 22Ne implanted in a 0.22 mm thick Ta backing, has been characterized using the 1222 keV and 458 keV resonances, well known in literature. Subsequently, the strengths of the resonances at 417, 458, 611, 632 and 1222 keV were determined. Two HPGe detectors equipped with active anti-Compton shielding have been used.

[Arthroscopic therapy of ankle joint impingement syndrome after operation of ankle joint fracture dislocation].

PubMed

Feng, Zhibin; Mi, Kun; Wei, Renzhi; Liu, Wu; Wang, Bin

2011-07-01

To study the operative procedure and the effectiveness of arthroscopic therapy for ankle joint impingement syndrome after operation of ankle joint fracture dislocation. Between March 2008 and April 2010, 38 patients with ankle joint impingement syndrome after operation of ankle joint fracture dislocation were treated. Among them, there were 28 males and 10 females with an average age of 28 years (range, 18 to 42 years). The time from internal fixation to admission was 12-16 months (mean, 13.8 months). There were pressing pain in anterolateral and anterior ankle. The dorsal extension ranged from -20 to -5 degrees (mean, -10.6 degrees), and the palmar flexion was 30-40 degrees (mean, 35.5 degrees). The total score was 48.32 +/- 9.24 and the pain score was 7.26 +/- 1.22 before operation according to American Orthopaedic Foot and Ankle Society (AOFAS) ankle and hindfoot score system. The X-ray films showed osteophyte formation in anterior tibia and talus; MRI showed cartilage injury in 22 cases. Arthroscopic intervention included removing osteophytes, debriding fabric scars and synovial membrane tissues, and removing osteochondral fragments. Arthroscopic microfracture technique was used in 22 patients with cartilage injury. All incisions healed primarily. Thirty-eight cases were followed up 10-26 months (mean, 16 months). At last follow-up, 26 patients had normal range of motion (ROM); the dorsal extension was 15-25 degrees (mean, 19.6 degrees) and the palmar flexion was 35-45 degrees (mean, 40.7 degrees). Eight patients had mild limited ROM; the dorsal extension was 5-15 degrees (mean, 7.2 degrees) and the palmar flexion was 35-45 degrees (mean, 39.5 degrees). Four patients had mild limited ROM and pain in posterior portion of the ankle after a long walking (3-4 hours); the dorsal extension was 0-5 degrees (mean, 2.6 degrees) and the palmar flexion was 35-40 degrees (mean, 37.5 degrees). The total score was 89.45 +/- 9.55 and the pain score was 1.42 +/- 1.26 after

Joint STS-79 & Mir 22 crew in-flight portrait

NASA Image and Video Library

1996-09-23

STS79-E-5289 (23 September 1996) --- Crew members of STS-79 and Mir-22 pose for final group portrait aboard Russia's Mir Space Station's Core Module before going separate ways in Earth-orbit, during Flight Day 8. Front row, left to right, are Aleksandr Y. Kaleri, Jerome (Jay) Apt, William F. Readdy and Shannon W. Lucid. On the back row are, left to right, Thomas D. Akers, Carl E. Walz, Valeri G. Korzun and Terrence W. Wilcutt. Note Blaha, the new cosmonaut researcher for Mir-22, is now wearing the uniform of that crew and Lucid's garment is uniform with the STS-79 astronauts.

22 CFR 401.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Definitions. 401.1 Section 401.1 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.1 Definitions. (a) In the construction of the regulations in this part, unless the context otherwise requires...

2+2 Electronics Technology. Looking Forward to the Future. A Model Secondary/Post-Secondary 2+2 Program To Prepare Students for Employment.

ERIC Educational Resources Information Center

Judson Independent School District, Converse, TX.

This document contains all pertinent information and essential background data necessary to implement the 2+2 electronics program at the high school level. An introduction describes development of the electronics technology 2+2 project that was a joint effort among San Antonio College and Judson, Northside, and North East Independent School…

Jointness: A Selected Bibliography

DTIC Science & Technology

2007-08-01

AD-A431-767) http://handle.dtic.mil/100.2/ADA431767 Lamb , William L. Moving beyond Goldwater-Nichols: The Case for Continued Reform of the DoD...in Support of the Joint Force’." Army Aviation 55 (May 2006): 22-24. Magnuson, Stew . "Turf Battles: Strategic Command’s Expanded Portfolio

29 CFR 791.2 - Joint employment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the employee by the other joint employer or employers. 4 Walling v. Friend, et al., 156 F. 2d 429 (C.... Hargrave, 129 F. 2d 655 (C.A. 10); Slover v. Wathen, 140 F. 2d 258 (C.A. 4); Mitchell v. Bowman, 131 F. Supp., 520 (M.D. Ala. 1954); Mitchell v. Thompson Materials & Construction Co., et al., 27 Labor Cases...

29 CFR 791.2 - Joint employment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the employee by the other joint employer or employers. 4 Walling v. Friend, et al., 156 F. 2d 429 (C.... Hargrave, 129 F. 2d 655 (C.A. 10); Slover v. Wathen, 140 F. 2d 258 (C.A. 4); Mitchell v. Bowman, 131 F. Supp., 520 (M.D. Ala. 1954); Mitchell v. Thompson Materials & Construction Co., et al., 27 Labor Cases...

29 CFR 791.2 - Joint employment.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the employee by the other joint employer or employers. 4 Walling v. Friend, et al., 156 F. 2d 429 (C.... Hargrave, 129 F. 2d 655 (C.A. 10); Slover v. Wathen, 140 F. 2d 258 (C.A. 4); Mitchell v. Bowman, 131 F. Supp., 520 (M.D. Ala. 1954); Mitchell v. Thompson Materials & Construction Co., et al., 27 Labor Cases...

29 CFR 791.2 - Joint employment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the employee by the other joint employer or employers. 4 Walling v. Friend, et al., 156 F. 2d 429 (C.... Hargrave, 129 F. 2d 655 (C.A. 10); Slover v. Wathen, 140 F. 2d 258 (C.A. 4); Mitchell v. Bowman, 131 F. Supp., 520 (M.D. Ala. 1954); Mitchell v. Thompson Materials & Construction Co., et al., 27 Labor Cases...

Organochlorine pesticides, polychlorinated biphenyls, and mercury in osprey eggs--1970-79--and their relationships to shell thinning and productivity

USGS Publications Warehouse

Wiemeyer, Stanley N.; Bunck, C.M.; Krynitsky, A.J.

1988-01-01

Osprey (Pandion haliaetus) eggs were collected in 14 states in 1970-79 and analyzed for organochlorine pesticides, polychlorinated biphenyls (PCBs), and mercury. Moderate shell thinning occurred in eggs from several areas. DDE was detected in all eggs, PCBs in 99%, DDD in 96%, dieldrin in 52%, and other compounds less frequently. Concentrations of DDT and its metabolites declined in eggs from Cape May County, New Jersey between 1970-72 and 1978-79. Eggs .from New Jersey in the early 1970s contained the highest concentrations of DDE. Dieldrin concentrations declined in eggs from the Potomac River, Maryland during 1971-77. Five different contaminants were significantly negatively correlated with shell thickness; DDE was most closely correlated. Ten percent shell thinning was associated with 2.0 ppm DDE, 15% with 4.2 ppm, and 20% with 8.7 ppm in eggs collected from randomly selected nests before egg loss. Shell thickness could not be accurately predicted from DDE concentrations in eggs collected after failure to hatch, presumably because the eggs with the thinnest shells had been broken and were unavailable for sampling. DDE was also significantly negatively correlated with brood size. Other contaminants did not appear to adversely affect shell thickness or reproductive success.

Microstructure characteristics and mechanical properties of laser-TIG hybrid welded dissimilar joints of Ti-22Al-27Nb and TA15

NASA Astrophysics Data System (ADS)

Zhang, Kezhao; Lei, Zhenglong; Chen, Yanbin; Liu, Ming; Liu, Yang

2015-10-01

Laser-TIG-hybrid-welding (TIG - tungsten inert gas) process was successfully applied to investigate the microstructure and tensile properties of Ti-22Al-27Nb/TA15 dissimilar joints. The HAZ of the arc zone in Ti-22Al-27Nb was characterized by three different regions: single B2, B2+α2 and B2+α2+O, while the single B2 phase region was absent in the HAZ of the laser zone. As for the HAZ in TA15 alloy, the microstructure mainly contained acicular α‧ martensites near the fusion line and partially remained the lamellar structure near the base metal. The fusion zone consisted of B2 phase due to the relatively high content of β phase stabilizing elements and fast cooling rate during the welding process. The tensile strength of the welds was higher than that of TA15 alloy because of the fully B2 microstructure in the fusion zone, and the fracture preferentially occurred on the base metal of TA15 alloy during the tensile tests at room temperature and 650 °C.

22 CFR 401.21 - Consultation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Consultation. 401.21 Section 401.21 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.21 Consultation. The Commission may meet or consult with the applicant, the Governments and other persons or their...

Wing force and surface pressure data from a hover test of a 0.658-scale V-22 rotor and wing

NASA Technical Reports Server (NTRS)

Felker, Fort F.; Shinoda, Patrick R.; Heffernan, Ruth M.; Sheehy, Hugh F.

1990-01-01

A hover test of a 0.658-scale V-22 rotor and wing was conducted in the 40 x 80 foot wind tunnel at Ames Research Center. The principal objective of the test was to measure the surface pressures and total download on a large scale V-22 wing in hover. The test configuration consisted of a single rotor and semispan wing on independent balance systems. A large image plane was used to represent the aircraft plane of symmetry. Wing flap angles ranging from 45 to 90 degrees were examined. Data were acquired for both directions of the rotor rotation relative to the wing. Steady and unsteady wing surface pressures, total wing forces, and rotor performance data are presented for all of the configurations that were tested.

Treatment of non-Hodgkin's lymphoma xenografts with the HB22.7 anti-CD22 monoclonal antibody and phosphatase inhibitors improves efficacy.

PubMed

O'Donnell, Robert T; Pearson, David; McKnight, Hayes C; Ma, Ya Peng; Tuscano, Joseph M

2009-10-01

To examine the role of phosphatase inhibition on anti-CD22, HB22.7-mediated lymphomacidal effects. CD22 is a cell-surface molecule expressed on most B cell lymphomas (NHL). HB22.7 is an anti-CD22 monoclonal antibody that binds a unique CD22-epitope, blocks ligand binding, initiates signaling, and has demonstrated lymphomacidal activity. The SHP-1 tyrosine phosphatase is associated with the cytoplasmic domain of CD22. Sodium orthovanadate (NaV) is a phosphatase inhibitor. The SHP-1-CD22 interaction presents an opportunity to manipulate CD22-mediated signaling effects. In vitro cell culture assays and in vivo human NHL xenograft studies were used to assess the effects of phosphatase inhibition. NaV caused dose dependent killing of NHL cells in vitro; when HB22.7 was given with NaV, antibody-mediated cell death was augmented. Flow cytometry showed that NaV-pretreatment resulted in less CD22 internalization after ligation with HB22.7 than did control cells. Studies in mice bearing Raji NHL xenografts showed that the combination of NaV and HB22.7 shrank NHL tumors more rapidly, had a higher complete response rate (80%), and produced the best survival compared to controls; no toxicity was detected. Studies using Raji cells stably transfected with SHP-1DN confirmed that these observations were due to SHP-1 inhibition. The relatively specific association of SHP-1 with CD22 suggests that CD22-specific signal augmentation by phosphatase inhibitors can improve the clinical outcome of anti-CD22 based immunotherapy.

22 CFR 401.29 - Hearings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Hearings. 401.29 Section 401.29 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE References § 401.29 Hearings. (a) A hearing or hearings may be held whenever in the opinion of the Commission such action would...

22 CFR 401.23 - Hearings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Hearings. 401.23 Section 401.23 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.23 Hearings. (a) The time and place of the hearing or hearings of an application shall be fixed by the...

22 CFR 401.5 - Meetings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Meetings. 401.5 Section 401.5 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.5 Meetings. (a) Subject at all times to special call or direction by the two Governments, meetings of the Commission shall...

Arthroscopic treatment of acute acromioclavicular joint dislocation by coracoclavicular ligament augmentation.

PubMed

Liu, Xudong; Huangfu, Xiaoqiao; Zhao, Jinzhong

2015-05-01

Coracoclavicular (CC) ligament augmentation has been a method to treat acromioclavicular (AC) joint dislocation in recent years. The purpose of this paper is to describe our arthroscopic CC ligament augmentation technique in treating type III and V acute AC joint dislocations and to report the early clinical and radiological results. From 2010 to 2011, twelve patients suffering from acute type III or V AC joint dislocations were arthroscopically treated in our department, by CC ligament augmentation after AC joint reduction. The post-operative outcomes were assessed through physical examination, radiographic examination and the Constant-Murley Shoulder Score. All patients post-operatively experienced anatomical reduction in their AC joint dislocation. No intraoperative complications occurred. At a mean follow-up at 24 months (ranging from 18 to 32 months), the mean Constant-Murley Shoulder Score significantly improved from 24.3 pre-operatively to 91.1 post-operatively. No neurovascular complications or secondary degenerative changes of the AC joint were detected in any of the patients. In one case, a second dislocation occurred 1 month post-operation because the patient had had another traumatic injury. This patient accepted a revision operation, but his AC joint eventually fixated into a subluxated position after his second injury. Based on the resultant successful repair in all cases, the arthroscopic CC ligament augmentation method has thus far proven to be a safe and reliable technique for treatment of acute type III or V AC joint dislocation. The arthroscopic CC ligament augmentation with a flip button/polyethylene belt repair is an efficient method to treat acute type III and V AC joint dislocations which should be popularized. IV.

The 21 Na (p,γ) 22 Mg reaction from Ec.m. =200 to 1103 keV in novae and x-ray bursts

NASA Astrophysics Data System (ADS)

D'Auria, J. M.; Azuma, R. E.; Bishop, S.; Buchmann, L.; Chatterjee, M. L.; Chen, A. A.; Engel, S.; Gigliotti, D.; Greife, U.; Hunter, D.; Hussein, A.; Hutcheon, D.; Jewett, C. C.; José, J.; King, J. D.; Laird, A. M.; Lamey, M.; Lewis, R.; Liu, W.; Olin, A.; Ottewell, D.; Parker, P.; Rogers, J.; Ruiz, C.; Trinczek, M.; Wrede, C.

2004-06-01

The long-lived radioactive nuclide 22 Na ( t1/2 =2.6 yr) is an astronomical observable for understanding the physical processes of oxygen-neon novae. Yields of 22Na in these events are sensitive to the unknown total rate of the 21 Na (p,γ) 22 Mg reaction. Using a high intensity 21 Na beam at the TRIUMF-ISAC facility, the strengths of seven resonances in 22 Mg , of potential astrophysical importance, have been directly measured at center of mass energies from Ec.m. =200 to 1103 keV . We report the results obtained for these resonances and their respective contributions to the 21 Na (p,γ) 22 Mg rate in novae and x-ray bursts, and their impact on 22 Na production in novae.

Failure Assessment Diagram for Titanium Brazed Joints

NASA Technical Reports Server (NTRS)

Flom, Yury; Jones, Justin S.; Powell, Mollie M.; Puckett, David F.

2011-01-01

The interaction equation was used to predict failure in Ti-4V-6Al joints brazed with Al 1100 filler metal. The joints used in this study were geometrically similar to the joints in the brazed beryllium metering structure considered for the ATLAS telescope. This study confirmed that the interaction equation R(sub sigma) + R(sub Tau) = 1, where R(sub sigma) and R(sub Tau)are normal and shear stress ratios, can be used as conservative lower bound estimate of the failure criterion in ATLAS brazed joints as well as for construction of the Failure Assessment Diagram (FAD).

22 CFR 1203.735-102 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Definitions. 1203.735-102 Section 1203.735-102... CONDUCT General Provisions § 1203.735-102 Definitions. (a) Agency means the United States International..., a society, a joint stock company, or any other organization or institution. (e) Special Government...

Whole-body vibration does not influence knee joint neuromuscular function or proprioception.

PubMed

Hannah, R; Minshull, C; Folland, J P

2013-02-01

This study examined the acute effects of whole-body vibration (WBV) on knee joint position sense and indices of neuromuscular function, specifically strength, electromechanical delay and the rate of force development. Electromyography and electrically evoked contractions were used to investigate neural and contractile responses to WBV. Fourteen healthy males completed two treatment conditions on separate occasions: (1) 5 × 1 min of unilateral isometric squat exercise on a synchronous vibrating platform [30 Hz, 4 mm peak-to-peak amplitude] (WBV) and (2) a control condition (CON) of the same exercise without WBV. Knee joint position sense (joint angle replication task) and quadriceps neuromuscular function were assessed pre-, immediately-post and 1 h post-exercise. During maximum voluntary knee extensions, the peak force (PF(V)), electromechanical delay (EMD(V)), rate of force development (RFD(V)) and EMG of the quadriceps were measured. Twitch contractions of the knee extensors were electrically evoked to assess EMD(E) and RFD(E). The results showed no influence of WBV on knee joint position, EMD(V), PF(V) and RFD(V) during the initial 50, 100 or 150 ms of contraction. Similarly, electrically evoked neuromuscular function and neural activation remained unchanged following the vibration exercise. A single session of unilateral WBV did not influence any indices of thigh muscle neuromuscular performance or knee joint proprioception. © 2011 John Wiley & Sons A/S.

USMC Electronic Warfare 2025: Trading Expertise for Advanced Technology

DTIC Science & Technology

2011-04-15

REFERENCES TO THIS STUDY SHOULD INCLUDE THE FOREGOING STATEMENT. QUOTATIONS FROM, ABSTRACTIONS FROM, OR REPRODUCTION OF ALL OR ANY PART OF THIS...formed with the.use of helicopters as nodes, including: MV-22B Ospreys, UH-1 Y Venoms, AH-1Z Vipers and CH-53K Super Stallions . The conceived benefits of

F-22 Plus-Up Environmental Assessment Joint Base Elmendorf-Richardson, Alaska

DTIC Science & Technology

2011-06-01

Page 1-3 The F-22 has enhanced low visibilty, speed, maneuverability, electronics , and maintainability. The proposal is to beddown six primary...tactics, radar employment, identification, weapons employment, defensive response, electronic countermeasures, and electronic counter countermeasures...flare, and electronic countermeasures. Warning Area, MOA, and ATCAA 2,000 AGL to 60,000 MSL 0.75 to 1.5 hour F-22 Plus-Up Environmental

The Acquisition Process as a Vehicle for Enabling Knowledge Management in the Lifecycle of Complex Federal Systems

NASA Technical Reports Server (NTRS)

Stewart, Helen; Spence, Matt Chew; Holm, Jeanne; Koga, Dennis (Technical Monitor)

2001-01-01

This white paper explores how to increase the success and operation of critical, complex, national systems by effectively capturing knowledge management requirements within the federal acquisition process. Although we focus on aerospace flight systems, the principles outlined within may have a general applicability to other critical federal systems as well. Fundamental design deficiencies in federal, mission-critical systems have contributed to recent, highly visible system failures, such as the V-22 Osprey and the Delta rocket family. These failures indicate that the current mechanisms for knowledge management and risk management are inadequate to meet the challenges imposed by the rising complexity of critical systems. Failures of aerospace system operations and vehicles may have been prevented or lessened through utilization of better knowledge management and information management techniques.

Rescuing Joint Personnel Recovery: Using Air Force Capability to Address Joint Shortfalls

DTIC Science & Technology

2011-06-01

of an IP, the IP is not successfully reintegrated or the lessons learned are not incorporated into other operations. Adversaries will benefit from...Washington, D.C.: Office of Air Force History , United States Air Force, 1980, 117. 47 Durant , Michael J. In the Company of Heroes, Penguin Group... Lessons Learned, 22 September 2005, 3. 2 US Joint Task Force Katrina. The Federal Response to Hurricane Katrina Lessons Learned, February 2006, 54

22 CFR 401.28 - Advisory boards.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Advisory boards. 401.28 Section 401.28 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE References § 401.28 Advisory boards. (a) The Commission may appoint a board or boards, composed of qualified persons, to...

22 CFR 401.13 - Copies required.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Copies required. 401.13 Section 401.13 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.13 Copies required. (a) Subject to paragraph (c) of this section, two duplicate originals and fifty copies...

22 CFR 401.10 - General rule.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true General rule. 401.10 Section 401.10 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.10 General rule. The Commission may, at any time, adopt any procedure which it deems expedient and necessary...

Post-operative bracing after ACL reconstruction has no effect on knee joint effusion. A prospective, randomized study.

PubMed

Lindström, Maria; Wredmark, Torsten; Wretling, Marie-Louise; Henriksson, Marketta; Felländer-Tsai, Li

2015-12-01

It is unclear what factors contribute to knee joint effusion after anterior cruciate ligament (ACL) injury and reconstruction. Knee homeostasis after injury and surgery is crucial for rehabilitation and knee well-being. We examined if effusion was affected by post-operative bracing, and if patients with effusion fit into a common profile. Patients were randomized to wearing or not wearing a post-operative brace for three weeks after ACL reconstruction with semitendinosus-gracilis tendons. Knee joint effusion was detected by computed tomography in 60 patients (22 women), before and three and 12 months after surgery. Joint effusion, clinical and subjective tests were analyzed. This is the first prospective, randomized study on post-operative bracing for patients with a semitendinosus-gracilis graft showed that bracing had no effect on three-months presence of joint effusion. Excessive joint effusion was present in 68% of the patients three months after surgery and was associated to prior meniscus injury (p=0.05) and higher prior Tegner activity level (p=0.006). We found a positive association between longer time from injury to surgery and joint effusion three months post-operatively (rho=0.29, p<0.05). Twelve months post-operatively, joint effusion had diminished to baseline levels. Subjective scores and activity levels were lower for women. Three-months joint effusion predicted lower final outcome scores in women. Prior meniscus injury and pre-injury Tegner activity levels are predictive significant variables for excessive knee joint effusion after ACL reconstruction. Post-operative bracing had no effect. A larger clinical cohort is needed to confirm findings of this logistic regression. Copyright © 2015 Elsevier B.V. All rights reserved.

77 FR 40410 - Open Meeting of the Taxpayer Advocacy Panel Joint Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-09

... DEPARTMENT OF THE TREASURY Internal Revenue Service Open Meeting of the Taxpayer Advocacy Panel... open meeting of the Taxpayer Advocacy Panel Joint Committee will be conducted. The Taxpayer Advocacy...) that an open meeting of the Taxpayer Advocacy Panel Joint Committee will be held Wednesday, August 22...

Joint angle affects volitional and magnetically-evoked neuromuscular performance differentially.

PubMed

Minshull, C; Rees, D; Gleeson, N P

2011-08-01

This study examined the volitional and magnetically-evoked neuromuscular performance of the quadriceps femoris at functional knee joint angles adjacent to full extension. Indices of volitional and magnetically-evoked neuromuscular performance (N=15 healthy males, 23.5 ± 2.9 years, 71.5 ± 5.4 kg, 176.5 ± 5.5 cm) were obtained at 25°, 35° and 45° of knee flexion. Results showed that volitional and magnetically-evoked peak force (PF(V) and P(T)F(E), respectively) and electromechanical delay (EMD(V) and EMD(E), respectively) were enhanced by increased knee flexion. However, greater relative improvements in volitional compared to evoked indices of neuromuscular performance were observed with increasing flexion from 25° to 45° (e.g. EMD(V), EMD(E): 36% vs. 11% improvement, respectively; F([2,14])=6.8, p<0.05). There were no significant correlations between EMD(V) and EMD(E) or PF(V) and P(T)F(E), at analogous joint positions. These findings suggest that the extent of the relative differential between volitional and evoked neuromuscular performance capabilities is joint angle-specific and not correlated with performance capabilities at adjacent angles, but tends to be smaller with increased flexion. As such, effective prediction of volitional from evoked performance capabilities at both analogous and adjacent knee joint positions would lack robustness. Copyright © 2011 Elsevier Ltd. All rights reserved.

Arch structure is associated with unique joint work, relative joint contributions and stiffness during landing.

PubMed

Powell, Douglas W; Queen, Robin M; Williams, D S Blaise

2016-10-01

To examine lower extremity joint contributions to a landing task in high-(HA) and low-arched (LA) female athletes by quantifying vertical stiffness, joint work and relative joint contributions to landing. Twenty healthy female recreational athletes (10 HA and 10 LA) performed five barefoot drop landings from a height of 30cm. Three-dimensional kinematics (240Hz) and ground reaction forces (960Hz) were recorded simultaneously. Vertical stiffness, joint work values and relative joint work values were calculated using Visual 3D and MatLab. HA athletes had significantly greater vertical stiffness compared to LA athletes (p=0.013). Though no differences in ankle joint work were observed (p=0.252), HA athletes had smaller magnitudes of knee (p=0.046), hip (p=0.019) and total lower extremity joint work values (p=0.016) compared to LA athletes. HA athletes had greater relative contributions of the ankle (p=0.032) and smaller relative contributions of the hip (p=0.049) compared to LA athletes. No differences in relative contributions of the knee were observed (p=0.255). These findings demonstrate that aberrant foot structure is associated with unique contributions of lower extremity joints to load attenuation during landing. These data may provide insight into the unique injury mechanisms associated with arch height in female athletes. Copyright © 2016 Elsevier B.V. All rights reserved.

22 CFR 401.11 - Availability of records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Availability of records. 401.11 Section 401.11 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General... shall be available for public information at the permanent offices of the Commission. Applications...

Quasi-Global Precipitation as Depicted in the GPCPV2.2 and TMPA V7

NASA Technical Reports Server (NTRS)

Huffman, George J.; Bolvin, David T.; Nelkin, Eric J.; Adler, Robert F.

2012-01-01

After a lengthy incubation period, the year 2012 saw the release of the Global Precipitation Climatology Project (GPCP) Version 2.2 monthly dataset and the TRMM Multi-satellite Precipitation Analysis (TMPA) Version 7. One primary feature of the new data sets is that DMSP SSMIS data are now used, which entailed a great deal of development work to overcome calibration issues. In addition, the GPCP V2.2 included a slight upgrade to the gauge analysis input datasets, particularly over China, while the TMPA V7 saw more-substantial upgrades: 1) The gauge analysis record in Version 6 used the (older) GPCP monitoring product through April 2005 and the CAMS analysis thereafter, which introduced an inhomogeneity. Version 7 uses the Version 6 GPCC Full analysis, switching to the Version 4 Monitoring analysis thereafter. 2) The inhomogeneously processed AMSU record in Version 6 is uniformly processed in Version 7. 3) The TMI and SSMI input data have been upgraded to the GPROF2010 algorithm. The global-change, water cycle, and other user communities are acutely interested in how these data sets compare, as consistency between differently processed, long-term, quasi-global data sets provides some assurance that the statistics computed from them provide a good representation of the atmosphere's behavior. Within resolution differences, the two data sets agree well over land as the gauge data (which tend to dominate the land results) are the same in both. Over ocean the results differ more because the satellite products used for calibration are based on very different algorithms and the dominant input data sets are different. The time series of tropical (30 N-S) ocean average precipitation shows that the TMPA V7 follows the TMI-PR Combined Product calibrator, although running approximately 5% higher on average. The GPCP and TMPA time series are fairly consistent, although the GPCP runs approximately 10% lower than the TMPA, and has a somewhat larger interannual variation. As well

On the Process-Related Rivet Microstructural Evolution, Material Flow and Mechanical Properties of Ti-6Al-4V/GFRP Friction-Riveted Joints.

PubMed

Borba, Natascha Z; Afonso, Conrado R M; Blaga, Lucian; Dos Santos, Jorge F; Canto, Leonardo B; Amancio-Filho, Sergio T

2017-02-15

In the current work, process-related thermo-mechanical changes in the rivet microstructure, joint local and global mechanical properties, and their correlation with the rivet plastic deformation regime were investigated for Ti-6Al-4V (rivet) and glass-fiber-reinforced polyester (GF-P) friction-riveted joints of a single polymeric base plate. Joints displaying similar quasi-static mechanical performance to conventional bolted joints were selected for detailed characterization. The mechanical performance was assessed on lap shear specimens, whereby the friction-riveted joints were connected with AA2198 gussets. Two levels of energy input were used, resulting in process temperatures varying from 460 ± 130 °C to 758 ± 56 °C and fast cooling rates (178 ± 15 °C/s, 59 ± 15 °C/s). A complex final microstructure was identified in the rivet. Whereas equiaxial α-grains with β-phase precipitated in their grain boundaries were identified in the rivet heat-affected zone, refined α' martensite, Widmanstätten structures and β-fleck domains were present in the plastically deformed rivet volume. The transition from equiaxed to acicular structures resulted in an increase of up to 24% in microhardness in comparison to the base material. A study on the rivet material flow through microtexture of the α-Ti phase and β-fleck orientation revealed a strong effect of shear stress and forging which induced simple shear deformation. By combining advanced microstructural analysis techniques with local mechanical testing and temperature measurement, the nature of the complex rivet plastic deformational regime could be determined.

On the Process-Related Rivet Microstructural Evolution, Material Flow and Mechanical Properties of Ti-6Al-4V/GFRP Friction-Riveted Joints

PubMed Central

Borba, Natascha Z.; Afonso, Conrado R. M.; Blaga, Lucian; dos Santos, Jorge F.; Canto, Leonardo B.; Amancio-Filho, Sergio T.

2017-01-01

In the current work, process-related thermo-mechanical changes in the rivet microstructure, joint local and global mechanical properties, and their correlation with the rivet plastic deformation regime were investigated for Ti-6Al-4V (rivet) and glass-fiber-reinforced polyester (GF-P) friction-riveted joints of a single polymeric base plate. Joints displaying similar quasi-static mechanical performance to conventional bolted joints were selected for detailed characterization. The mechanical performance was assessed on lap shear specimens, whereby the friction-riveted joints were connected with AA2198 gussets. Two levels of energy input were used, resulting in process temperatures varying from 460 ± 130 °C to 758 ± 56 °C and fast cooling rates (178 ± 15 °C/s, 59 ± 15 °C/s). A complex final microstructure was identified in the rivet. Whereas equiaxial α-grains with β-phase precipitated in their grain boundaries were identified in the rivet heat-affected zone, refined α′ martensite, Widmanstätten structures and β-fleck domains were present in the plastically deformed rivet volume. The transition from equiaxed to acicular structures resulted in an increase of up to 24% in microhardness in comparison to the base material. A study on the rivet material flow through microtexture of the α-Ti phase and β-fleck orientation revealed a strong effect of shear stress and forging which induced simple shear deformation. By combining advanced microstructural analysis techniques with local mechanical testing and temperature measurement, the nature of the complex rivet plastic deformational regime could be determined. PMID:28772545

Joint reproductive autonomy: does Evans v Amicus Healthcare Ltd provide for a gender-neutral approach to assisted reproductive rights?

PubMed

Allin, Michael J

2015-06-01

Assisted reproductive technology encompasses methods of achieving pregnancy by artificial or partially artificial means. Whilst these methods are more commonly used by couples suffering from problems of infertility, some forms of assistance are employed by fertile couples, for example pre-implantation genetic diagnosis. The overall regulatory framework in the UK is predominantly found in the Human Fertilisation and Embryology Act 1990. The usual rules relating to consent and autonomy apply and were discussed in depth in Evans v Amicus Healthcare Ltd and later in Evans v United Kingdom. This paper considers whether the Evans litigation envisages the possibility of further encouraging joint autonomy in the use of zygotes and whether there is a continuing right to autonomy by the party not bearing the pregnancy. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

KSC-04pd1258

NASA Image and Video Library

2004-06-10

KENNEDY SPACE CENTER, FLA. - An osprey stares intently at prey as it extends its talons. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground, often near water. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

KSC-04PD-1258

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. An osprey stares intently at prey as it extends its talons. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground, often near water. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

The novel product of a five-exon stargazin-related gene abolishes CaV2.2 calcium channel expression

PubMed Central

Moss, Fraser J.; Viard, Patricia; Davies, Anthony; Bertaso, Federica; Page, Karen M.; Graham, Alex; Cantí, Carles; Plumpton, Mary; Plumpton, Christopher; Clare, Jeffrey J.; Dolphin, Annette C.

2002-01-01

We have cloned and characterized a new member of the voltage-dependent Ca2+ channel γ subunit family, with a novel gene structure and striking properties. Unlike the genes of other potential γ subunits identified by their homology to the stargazin gene, CACNG7 is a five-, and not four-exon gene whose mRNA encodes a protein we have designated γ7. Expression of human γ7 has been localized specifically to brain. N-type current through CaV2.2 channels was almost abolished when co-expressed transiently with γ7 in either Xenopus oocytes or COS-7 cells. Furthermore, immunocytochemistry and western blots show that γ7 has this effect by causing a large reduction in expression of CaV2.2 rather than by interfering with trafficking or biophysical properties of the channel. No effect of transiently expressed γ7 was observed on pre-existing endogenous N-type calcium channels in sympathetic neurones. Low homology to the stargazin-like γ subunits, different gene structure and the unique functional properties of γ7 imply that it represents a distinct subdivision of the family of proteins identified by their structural and sequence homology to stargazin. PMID:11927536

36 CFR 14.22 - Reimbursement of costs.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., more than one person, partnership, corporation, association or other entity apply together for a right... authorized officer, is one right-of-way system, all the applicants shall be jointly and severally liable for... Section 14.22 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR RIGHTS...

22 CFR 401.24 - Expenses of proceedings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Expenses of proceedings. 401.24 Section 401.24 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.24 Expenses of proceedings. (a) The expenses of those participating in any proceeding under this...

22 CFR 401.15 - Notice of publication.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Notice of publication. 401.15 Section 401.15 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.15 Notice of publication. (a) As soon as practicable after an application is presented or...

22 CFR 401.14 - Authorization by Government.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Authorization by Government. 401.14 Section 401.14 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.14 Authorization by Government. (a) Where the use, obstruction or diversion of waters for...

17 CFR 250.22 - Applications and declarations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... § 250.22 Applications and declarations. (a) Joinder. As far as practicable combined or joint applications or declarations shall be filed with respect to the same or related transactions or where related... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Applications and declarations...

Leakproof Swaged Joints in Thin-Wall Tubing

NASA Technical Reports Server (NTRS)

Stuckenberg, F. H.; Crockett, L. K.; Snyder, W. E.

1986-01-01

Tubular inserts reinforce joints, reducing incidence of leaks. In new swaging technique, tubular inserts placed inside ends of both tubes to be joined. Made from thicker-wall tubing with outside diameter that matches inside diameter of thin tubing swaged, inserts support tube ends at joint. They ensure more uniform contact between swage fitting and tubing. New swaging technique developed for Al/Ti/V-alloy hydraulic supply lines.

22 CFR 401.16 - Statement in response.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Statement in response. 401.16 Section 401.16 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.16 Statement in response. (a) Except as otherwise provided pursuant to § 410.19, a Government and...

22 CFR 401.7 - Conduct of hearings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Conduct of hearings. 401.7 Section 401.7 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.7 Conduct of hearings. Hearings may be conducted, testimony received and arguments thereon heard by the...

22 CFR 401.17 - Statement in reply.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Statement in reply. 401.17 Section 401.17 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.17 Statement in reply. (a) Except as otherwise provided pursuant to § 410.19, the applicant and...

22 CFR 401.27 - Notice and publication.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Notice and publication. 401.27 Section 401.27 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE References § 401.27 Notice and publication. (a) The secretary to whom a reference is presented shall receive and...

22 CFR 401.6 - Service of documents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Service of documents. 401.6 Section 401.6 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.6 Service of documents. (a) Where the secretary is required by the regulations in this part to...

Design and clinical outcome of a novel 3D-printed prosthetic joint replacement for the human temporomandibular joint.

PubMed

Ackland, David; Robinson, Dale; Lee, Peter Vee Sin; Dimitroulis, George

2018-05-11

Stock prosthetic temporomandibular joint replacements come in limited sizes, and do not always encompass the joint anatomy that presents clinically. The aims of this study were twofold. Firstly, to design a personalized prosthetic total joint replacement for the treatment of a patient's end-stage temporomandibular joint osteoarthritis, to implant the prosthesis into the patient, and assess clinical outcome 12-months post-operatively; and secondly, to evaluate the influence of changes in prosthetic condyle geometry on implant load response during mastication. A 48-year-old female patient with Grade-5 osteoarthritis to the left temporomandibular joint was recruited, and a prosthesis developed to match the native temporomandibular joint anatomy. The prosthesis was 3D printed, sterilized and implanted into the patient, and pain and function measured 12-months post-operatively. The prosthesis load response during a chewing-bite and maximum-force bite was evaluated using a personalized multi-body musculoskeletal model. Simulations were performed after perturbing condyle thickness, neck length and head sphericity. Increases in prosthetic condyle neck length malaligned the mandible and perturbed temporomandibular joint force. Changes in condylar component thickness greatly influenced fixation screw stress response, while a more eccentric condylar head increased prosthetic joint-contact loading. Post-operatively, the prosthetic temporomandibular joint surgery reduced patient pain from 7/10 to 1/10 on a visual analog scale, and increased intercisal opening distance from 22 mm to 38 mm. This study demonstrates effectiveness of a personalized prosthesis that may ultimately be adapted to treat a wide-range of end-stage temporomandibular joint conditions, and highlights sensitivity of prosthesis load response to changes in condylar geometry. Copyright © 2018 Elsevier Ltd. All rights reserved.

Management of chronic unstable acromioclavicular joint injuries.

PubMed

Cisneros, Luis Natera; Reiriz, Juan Sarasquete

2017-12-01

The acromioclavicular joint represents the link between the clavicle and the scapula, which is responsible for the synchronized dynamic of the shoulder girdle. Chronic acromioclavicular joint instability involves changes in the orientation of the scapula, which provokes cinematic alterations that might result in chronic pain. Several surgical strategies for the management of patients with chronic and symptomatic acromioclavicular joint instability have been described. The range of possibilities includes anatomical and non-anatomical techniques, open and arthroscopy-assisted procedures, and biological and synthetic grafts. Surgical management of chronic acromioclavicular joint instability should involve the reconstruction of the torn ligaments because it is accepted that from three weeks after the injury, these structures may lack healing potential. Here, we provide a review of the literature regarding the management of chronic acromioclavicular joint instability. Expert opinion, Level V.

24Na at Ex=4.7 -5.9 MeV from 22Ne(3He,p )

NASA Astrophysics Data System (ADS)

Fortune, H. T.

2018-04-01

Abstract. Analysis of data from the 22Ne(3He,p ) 24Na reaction has been extended to include 18 angular distributions for states between 4.7 and 5.9 MeV. A distorted-wave Born-approximation analysis allows the determination of ℓ value(s) for most of them. Results for Jπ are compared with previous information. In general, agreement is good. Some apparent disagreements between current and past results are indicative of population of a different state in this reaction than the nearby one listed in the compilation.

Demonstration of movement in the sacroiliac joint using ultrasound

NASA Astrophysics Data System (ADS)

Krupinski, Elizabeth A.; Brooks, William J.; Lund, Pamela J.

1995-05-01

The goal of this study was to demonstrate quantitatively, using ultrasound (US) recording techniques, the extent of motion of the sacroiliac joint achieved using manual medicine techniques. Initial judgements of perceived (i.e., felt) SI mobility during manual examination were made on 22 subjects. Baseline no movement ultrasound images (static) were obtained of the left and right SI joints at two levels-- posterior-superior-iliac-spine and inferior (PSIS, INF)--and two projections (AP and LAT). Manual medicine spring testing of the SI joint was then performed while ultrasound recordings (on video) were made. The differences between baseline separation of the SI joint and displacement distance during spring testing were measured by six radiologists who typically read US images. Significant movement of at least one SI joint was demonstrated in 91% of the subjects using ultrasound recordings. The extent of movement appeared to corroborate the experience of manual medicine practitioners.

Computer guided restoration of joint line and femoral offset in cruciate substituting total knee arthroplasty.

PubMed

Shetty, Gautam M; Mullaji, Arun; Bhayde, Sagar

2012-10-01

This prospective study aimed to evaluate radiographically, change in joint line and femoral condylar offset with the optimized gap balancing technique in computer-assisted, primary, cruciate-substituting total knee arthroplasties (TKAs). One hundred and twenty-nine consecutive computer-assisted TKAs were evaluated radiographically using pre- and postoperative full-length standing hip-to-ankle, antero-posterior and lateral radiographs to assess change in knee deformity, joint line height and posterior condylar offset. In 49% of knees, there was a net decrease (mean 2.2mm, range 0.2-8.4mm) in joint line height postoperatively whereas 46.5% of knees had a net increase in joint line height (mean 2.5mm, range 0.2-11.2mm). In 93% of the knees, joint line was restored to within ± 5 mm of preoperative values. In 53% of knees, there was a net increase (mean 2.9 mm, range 0.2-12 mm) in posterior offset postoperatively whereas 40% of knees had a net decrease in posterior offset (mean 4.2mm, range 0.6-20mm). In 82% of knees, the posterior offset was restored within ± 5 mm of preoperative values. Based on radiographic evaluation in extension and at 30° flexion, the current study clearly demonstrates that joint line and posterior femoral condylar offset can be restored in the majority of computer-assisted, cruciate-substituting TKAs to within 5mm of their preoperative value. The optimized gap balancing feature of the computer software allows the surgeon to simulate the effect of simultaneously adjusting femoral component size, position and distal femoral resection level on joint line and posterior femoral offset. Copyright © 2011 Elsevier B.V. All rights reserved.

Development of an innovative method to predict and to characterize the performances of Ti-6Al-4V LBW joints

NASA Astrophysics Data System (ADS)

Liberini, Mariacira; Esposito, Sara; Reshad, Kambitz; Previtali, Barbara; Viola, Marco; Squillace, Antonino

2016-10-01

Every manufacturing process leaves on the surface of the piece a typical "technology signature". In particular, the laser welding leaves a feature at the edge of the weld bead called "undercut". In this work an experimental campaign has been conducted on Ti6Al4V butt joints. In particular a Central Composite Design (CCD) with the central point repeated three times has been investigated. In the CCD there are two factors (power and speed of the fiber laser) and five levels for each factor. This paper deals with the investigation about the correlation between the severity of the undercut and the process parameters of the laser welding. In particular, through the confocal microscopy, the original geometry of the joint was accurately acquired and rebuilt in order to make a FEM model and simulate the mechanical behavior using Ansys14.5. Moreover, response surfaces and level curves were carried out to understand and predict the depth and the width of the undercut starting from the power and the speed of the laser. At last a mathematic and geometry regression was performed in order to find a unique conical curve that interpolates all the different undercuts and that varies its parameters according to the process parameters. It is established that the process with higher speed minimizes and optimizes the undercut in the joints.

Electromigration in solder joints and solder lines

NASA Astrophysics Data System (ADS)

Gan, H.; Choi, W. J.; Xu, G.; Tu, K. N.

2002-06-01

Electromigration may affect the reliability of flip-chip solder joints. Eutectic solder is a two-phase alloy, so its electromigration behavior is different from that in aluminum or copper interconnects. In addition, a flipchip solder joint has a built-in currentcrowding configuration to enhance electromigration failure. To better understand electromigration in SnPb and lead-free solder alloys, the authors prepared solder lines in v-grooves etched on Si (001). This article discusses the results of those tests and compares the electromigration failure modes of eutectic SnPb and SnAgCu flip-chip solder joints along with the mean-timeto-failure.

KSC-06pd0836

NASA Image and Video Library

2006-05-15

KENNEDY SPACE CENTER, FLA. -- These osprey chicks wait for lunch from one of their parents (look for the fish in the claws of the upper osprey). The nest is located on a pole in the parking lot of the NASA News Center. This is the third year the ospreys have raised a family at the site. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge, which shares a boundary with the Center. Photo credit: NASA/George Shelton

Is coracoclavicular stabilisation alone sufficient for the endoscopic treatment of severe acromioclavicular joint dislocation (Rockwood types III, IV, and V)?

PubMed

Barth, J; Duparc, F; Andrieu, K; Duport, M; Toussaint, B; Bertiaux, S; Clavert, P; Gastaud, O; Brassart, N; Beaudouin, E; De Mourgues, P; Berne, D; Bahurel, J; Najihi, N; Boyer, P; Faivre, B; Meyer, A; Nourissat, G; Poulain, S; Bruchou, F; Ménard, J F

2015-12-01

The primary objective was to evaluate correlations linking anatomical to functional outcomes after endoscopically assisted repair of acute acromioclavicular joint dislocation (ACJD). Combined acromioclavicular and coracoclavicular stabilisation improves radiological outcomes compared to coracoclavicular stabilisation alone. A prospective multicentre study was performed. Clinical outcome measures were pain intensity on a visual analogue scale (VAS), subjective functional impairment (QuickDASH score), and Constant's score. Anatomical outcomes were assessed on standard radiographs (anteroposterior view of the acromioclavicular girdle and bilateral axillary views) obtained preoperatively and postoperatively and on postoperative dynamic radiographs taken as described by Tauber et al. Of 116 patients with acute ACJD included in the study, 48% had type III, 30% type IV, and 22% type V ACJD according to the Rockwood classification. Coracoclavicular stabilisation was achieved using a double endobutton in 93% of patients, and concomitant acromioclavicular stabilisation was performed in 50% of patients. The objective functional outcome was good, with an unweighted Constant's score ≥ 85/100 and a subjective QuickDASH functional disability score ≤ 10 in 75% of patients. The radiographic analysis showed significant improvements from the preoperative to the 1-year postoperative values in the vertical plane (decrease in the coracoclavicular ratio from 214 to 128%, p=10(-6)) and in the horizontal plane (decrease in posterior displacement from 4 to 0mm, p=5×10(-5)). The anatomical outcome correlated significantly with the functional outcome (absolute R value=0.19 and p=0.045). We found no statistically significant differences across the various types of constructs used. Intra-operative control of the acromioclavicular joint did not improve the result. Implantation of a biological graft significantly improved both the anatomical outcome in the vertical plane (p=0.04) and

Trojan horse measurement of the 10B(p ,α0)7Be cross section in the energy range from 3 keV to 2.2 MeV

NASA Astrophysics Data System (ADS)

Cvetinović, A.; Spitaleri, C.; Spartá, R.; Rapisarda, G. G.; Puglia, S. M. R.; La Cognata, M.; Cherubini, S.; Guardo, G. L.; Gulino, M.; Lamia, L.; Pizzone, R. G.; Romano, S.; Sergi, M. L.; Tumino, A.

2018-06-01

The 10B(p ,α0)7Be excitation function has been studied in a wide energy range, from 2.2 MeV down to astrophysical energies, reproducing the cross section above and below the Coulomb barrier in a single experiment. An optimized experimental setup ensured good energy resolution and for the first time a clear separation of α0 and α1 channels of the 10B+2H interaction has been achieved by applying the Trojan Horse method. An improved normalization of the Trojan Horse bare-nucleus astrophysical S (E )-factor to direct data was performed and a value of Ue=391 ±74 eV was obtained for the electron screening potential.

Multivalent Interactions of Human Primary Amine Oxidase with the V and C22 Domains of Sialic Acid-Binding Immunoglobulin-Like Lectin-9 Regulate Its Binding and Amine Oxidase Activity

PubMed Central

Fair-Mäkelä, Ruth; Salo-Ahen, Outi M. H.; Guédez, Gabriela; Bligt-Lindén, Eva; Grönholm, Janne; Jalkanen, Sirpa; Salminen, Tiina A.

2016-01-01

Sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on leukocyte surface is a counter-receptor for endothelial cell surface adhesin, human primary amine oxidase (hAOC3), a target protein for anti-inflammatory agents. This interaction can be used to detect inflammation and cancer in vivo, since the labeled peptides derived from the second C2 domain (C22) of Siglec-9 specifically bind to the inflammation-inducible hAOC3. As limited knowledge on the interaction between Siglec-9 and hAOC3 has hampered both hAOC3-targeted drug design and in vivo imaging applications, we have now produced and purified the extracellular region of Siglec-9 (Siglec-9-EC) consisting of the V, C21 and C22 domains, modeled its 3D structure and characterized the hAOC3–Siglec-9 interactions using biophysical methods and activity/inhibition assays. Our results assign individual, previously unknown roles for the V and C22 domains. The V domain is responsible for the unusually tight Siglec-9–hAOC3 interactions whereas the intact C22 domain of Siglec-9 is required for modulating the enzymatic activity of hAOC3, crucial for the hAOC3-mediated leukocyte trafficking. By characterizing the Siglec-9-EC mutants, we could conclude that R120 in the V domain likely interacts with the terminal sialic acids of hAOC3 attached glycans whereas residues R284 and R290 in C22 are involved in the interactions with the active site channel of hAOC3. Furthermore, the C22 domain binding enhances the enzymatic activity of hAOC3 although the sialic acid-binding capacity of the V domain of Siglec-9 is abolished by the R120S mutation. To conclude, our results prove that the V and C22 domains of Siglec-9-EC interact with hAOC3 in a multifaceted and unique way, forming both glycan-mediated and direct protein-protein interactions, respectively. The reported results on the mechanism of the Siglec-9–hAOC3 interaction are valuable for the development of hAOC3-targeted therapeutics and diagnostic tools. PMID:27893774

[Viscosity determination of synovial fluids from the canine hip and elbow joint as well as the human knee joint].

PubMed

Helms, Gabriele; Rittmann, Pia; Wefstaedt, Patrick; Windhagen, Henning; Pressel, Thomas; Behrens, Bernd-Arno; Nolte, Ingo

2008-01-01

The development of pathological changes in both human and canine hip joints is mainly caused by a lack of synovial fluid lubrication. This results in an increased joint abrasion. Even after implantation of joint prosthesis, inadequate lubrication can lead to abrasion in the tribological pair. This can finally result in aseptic loosening of the prosthesis. In spite of the enormous number of studies that have been performed on human, only little knowledge about the tribological properties of the joints in dogs is available in the literature. For this reason the viscosities of synovial fluid, derived from physiological and pathologically changed canine elbow joints were measured. The viscosities were determined by the use of a cone-plate viscometer at different temperatures and shear rates. The obtained values were compared with the viscosity values of pathologically changed synovial fluids from human knee joints as well as with pathological samples from the canine hip joint. The results show that the viscosity values vary within a series of measurements and are inversely proportional to the temperature of the sample and the shear rate. The differences between the average viscosities of canine and human synovial fluids taken from pathologically changed joints are below 4% (22.5 s(-1) at theta1 = 25 degrees C). The findings of this study are being implemented in a FE-Model for the computation of actual forces in the hip joint during different movements. This would represent a contribution to an improved prosthetic treatment of canine and human hips.

KSC-04pd1216

NASA Image and Video Library

2004-05-18

KENNEDY SPACE CENTER, FLA. -- A fledgling osprey soars above its nest, located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04pd1143

NASA Image and Video Library

2004-05-14

KENNEDY SPACE CENTER, FLA. -- - Three osprey fledglings are ready to test their wings from the nest at the NASA News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04PD-1143

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- Three osprey fledglings are ready to test their wings from the nest at the NASA News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04PD-1216

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- A fledgling osprey soars above its nest, located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

Bright high-repetition-rate source of narrowband extreme-ultraviolet harmonics beyond 22 eV

PubMed Central

Wang, He; Xu, Yiming; Ulonska, Stefan; Robinson, Joseph S.; Ranitovic, Predrag; Kaindl, Robert A.

2015-01-01

Novel table-top sources of extreme-ultraviolet light based on high-harmonic generation yield unique insight into the fundamental properties of molecules, nanomaterials or correlated solids, and enable advanced applications in imaging or metrology. Extending high-harmonic generation to high repetition rates portends great experimental benefits, yet efficient extreme-ultraviolet conversion of correspondingly weak driving pulses is challenging. Here, we demonstrate a highly-efficient source of femtosecond extreme-ultraviolet pulses at 50-kHz repetition rate, utilizing the ultraviolet second-harmonic focused tightly into Kr gas. In this cascaded scheme, a photon flux beyond ≈3 × 1013 s−1 is generated at 22.3 eV, with 5 × 10−5 conversion efficiency that surpasses similar harmonics directly driven by the fundamental by two orders-of-magnitude. The enhancement arises from both wavelength scaling of the atomic dipole and improved spatio-temporal phase matching, confirmed by simulations. Spectral isolation of a single 72-meV-wide harmonic renders this bright, 50-kHz extreme-ultraviolet source a powerful tool for ultrafast photoemission, nanoscale imaging and other applications. PMID:26067922

Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer.

PubMed

Khurana, Namrata; Kim, Hogyoung; Chandra, Partha K; Talwar, Sudha; Sharma, Pankaj; Abdel-Mageed, Asim B; Sikka, Suresh C; Mondal, Debasis

2017-11-01

Prostate cancer (PCa) cells expressing full-length androgen receptor (AR-FL) are susceptible to androgen deprivation therapy (ADT). However, outgrowth of castration-resistant prostate cancer (CRPC) can occur due to the expression of constitutively active (ligand-independent) AR splice variants, particularly AR-V7. We previously demonstrated that sulforaphane (SFN), an isothiocyanate phytochemical, can decrease AR-FL levels in the PCa cell lines, LNCaP and C4-2B. Here, we examined the efficacy of SFN in targeting both AR-FL and AR-V7 in the CRPC cell line, CWR22Rv1 (22Rv1). MTT cell viability, wound-heal assay, and colony forming unit (CFU) measurements revealed that 22Rv1 cells are resistant to the anti-androgen, enzalutamide (ENZ). However, co-exposure to SFN sensitized these cells to the potent anticancer effects of ENZ (P<0.05). Immunoblot analyses showed that SFN (5-20 µM) rapidly decreases both AR-FL and AR-V7 levels, and immunofluorescence microscopy (IFM) depicted decreased AR in both cytoplasm and nucleus with SFN treatment. SFN increased both ubiquitination and proteasomal activity in 22Rv1 cells. Studies using a protein synthesis inhibitor (cycloheximide) or a proteasomal inhibitor (MG132) indicated that SFN increases both ubiquitin-mediated aggregation and subsequent proteasomal-degradation of AR proteins. Previous studies reported that SFN inhibits the chaperone activity of heat-shock protein 90 (Hsp90) and induces the nuclear factor erythroid-2-like 2 (Nrf2) transcription factor. Therefore, we investigated whether the Hsp90 inhibitor, ganetespib (G) or the Nrf2 activator, bardoxolone methyl (BM) can similarly suppress AR levels in 22Rv1 cells. Low doses of G and BM, alone or in combination, decreased both AR-FL and AR-V7 levels, and combined exposure to G+BM sensitized 22Rv1 cells to ENZ. Therefore, adjunct treatment with the phytochemical SFN or a safe pharmaceutical combination of G+BM may be effective against CRPC cells, especially those

Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer

PubMed Central

Khurana, Namrata; Kim, Hogyoung; Chandra, Partha K.; Talwar, Sudha; Sharma, Pankaj; Abdel-Mageed, Asim B.; Sikka, Suresh C.; Mondal, Debasis

2017-01-01

Prostate cancer (PCa) cells expressing full-length androgen receptor (AR-FL) are susceptible to androgen deprivation therapy (ADT). However, outgrowth of castration-resistant prostate cancer (CRPC) can occur due to the expression of constitutively active (ligand-independent) AR splice variants, particularly AR-V7. We previously demonstrated that sulforaphane (SFN), an isothiocyanate phytochemical, can decrease AR-FL levels in the PCa cell lines, LNCaP and C4-2B. Here, we examined the efficacy of SFN in targeting both AR-FL and AR-V7 in the CRPC cell line, CWR22Rv1 (22Rv1). MTT cell viability, wound-heal assay, and colony forming unit (CFU) measurements revealed that 22Rv1 cells are resistant to the anti-androgen, enzalutamide (ENZ). However, co-exposure to SFN sensitized these cells to the potent anticancer effects of ENZ (P<0.05). Immunoblot analyses showed that SFN (5–20 µM) rapidly decreases both AR-FL and AR-V7 levels, and immunofluorescence microscopy (IFM) depicted decreased AR in both cytoplasm and nucleus with SFN treatment. SFN increased both ubiquitination and proteasomal activity in 22Rv1 cells. Studies using a protein synthesis inhibitor (cycloheximide) or a proteasomal inhibitor (MG132) indicated that SFN increases both ubiquitin-mediated aggregation and subsequent proteasomal-degradation of AR proteins. Previous studies reported that SFN inhibits the chaperone activity of heat-shock protein 90 (Hsp90) and induces the nuclear factor erythroid-2-like 2 (Nrf2) transcription factor. Therefore, we investigated whether the Hsp90 inhibitor, ganetespib (G) or the Nrf2 activator, bardoxolone methyl (BM) can similarly suppress AR levels in 22Rv1 cells. Low doses of G and BM, alone or in combination, decreased both AR-FL and AR-V7 levels, and combined exposure to G+BM sensitized 22Rv1 cells to ENZ. Therefore, adjunct treatment with the phytochemical SFN or a safe pharmaceutical combination of G+BM may be effective against CRPC cells, especially those

Joint contact forces can be reduced by improving joint moment symmetry in below-knee amputee gait simulations.

PubMed

Koelewijn, Anne D; van den Bogert, Antonie J

2016-09-01

Despite having a fully functional knee and hip in both legs, asymmetries in joint moments of the knee and hip are often seen in gait of persons with a unilateral transtibial amputation (TTA), possibly resulting in excessive joint loading. We hypothesize that persons with a TTA can walk with more symmetric joint moments at the cost of increased effort or abnormal kinematics. The hypothesis was tested using predictive simulations of gait. Open loop controls of one gait cycle were found by solving an optimization problem that minimizes a combination of walking effort and tracking error in joint angles, ground reaction force and gait cycle duration. A second objective was added to penalize joint moment asymmetry, creating a multi-objective optimization problem. A Pareto front was constructed by changing the weights of the objectives and three solutions were analyzed to study the effect of increasing joint moment symmetry. When the optimization placed more weight on moment symmetry, walking effort increased and kinematics became less normal, confirming the hypothesis. TTA gait improved with a moderate increase in joint moment symmetry. At a small cost of effort and abnormal kinematics, the peak hip extension moment in the intact leg was decreased significantly, and so was the joint contact force in the knee and hip. Additional symmetry required a significant increase in walking effort and the joint contact forces in both hips became significantly higher than in able-bodied gait. Copyright © 2016 Elsevier B.V. All rights reserved.

PREFACE: International Conference on High Pressure Science and Technology, Joint AIRAPT-22 & HPCJ-50

NASA Astrophysics Data System (ADS)

Viña, Luis; Tejedor, Carlos; Calleja, José M.

2010-01-01

The International Joint AIRAPT-22 & HPCJ-50 Conference was held in Odaiba, Tokyo, on 26-31 July 2009. About 480 scientists from 24 countries attended the conference and 464 papers, including 3 plenary lectures, 39 invited talks, and 156 oral presentations, were presented. It is my great pleasure to present this proceedings volume, which is based on the high quality scientific works presented at the conference. The International AIRAPT conference has been held every two years in various countries around the world since 1965, while High Pressure Conference of Japan (HPCJ) has been held annually since 1959 in various Japanese cities. Pressure is a fundamental parameter to control the property of matter. As a result, both AIRAPT and HPCJ have become highly multidisciplinary, and cover Physics, Chemistry, Materials Science, Earth and Planetary Sciences, Biosciences, Food Science, and Technology. Although each discipline has a unique target, they all have high-pressure research in common. This proceedings volume includes about 200 papers of state-of-the-art studies from numerous fields. I hope this proceedings volume provides excellent pieces of information in various fields to further advance high-pressure research. Conference logo Takehiko Yagi Conference Chairman Institute for Solid State Physics The University of Tokyo 7 December 2009 Conference photograph Participants at the conference venue, Tokyo International Exchange Center, Odaiba, Tokyo, Japan. Editor in Chief TAKEMURA Kenichi National Institute for Materials Science, Japan Editorial board Tadashi KONDO Osaka University, Japan Hitoshi MATSUKI The University of Tokushima, Japan Nobuyuki MATUBAYASI Kyoto University, Japan Yoshihisa MORI Okayama University of Science, Japan Osamu OHTAKA Osaka University, Japan Chihiro SEKINE Muroran Institute of Technology, Japan

Acceleration of polarized protons to 22 GeV/c and the measurement of spin-spin effects in p/sub up-arrow/+p/sub up-arrow/. -->. p+p

DOE Office of Scientific and Technical Information (OSTI.GOV)

Khiari, F.Z.; Cameron, P.R.; Court, G.R.

1989-01-01

Accelerating polarized protons to 22 GeV/c at the Brookhaven Alternating Gradient Synchro- tron required both extensive hardware modifications and a difficult commissioning process. We had to overcome 45 strong depolarizing resonances to maintain polarization up to 22 GeV/c in this strong-focusing synchrotron. At 18.5 GeV/c we measured the analyzing power A and the spin-spin correlation parameter A/sub n//sub n/ in large- P/sub perpendicular//sup 2/ proton-proton elastic scattering, using the polarized proton beam and a polarized proton target. We also obtained a high-precision measurement of A at P/sub perpendicular//sup 2/ = 0.3 (GeV/c)/sup 2/ at 13.3 GeV/c. At 18.5 GeV/c wemore » found that A/sub n//sub n/ = (-2 +- 16)% at P/sub perpendicular//sup 2/ = 4.7 (GeV/c)/sup 2/, where it was about 60% near 12 GeV at the Argonne Zero Gradient Synchrotron. This sharp change suggests that spin-spin forces may have a strong and unexpected energy dependence at high P/sub perpendicular//sup 2/.« less

22 CFR 401.20 - Interested persons and counsel.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Interested persons and counsel. 401.20 Section 401.20 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.20 Interested persons and counsel. Governments and persons interested in the subject matter...

22 CFR 1004.3 - Requirement of open meetings.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Requirement of open meetings. 1004.3 Section 1004.3 Foreign Relations INTER-AMERICAN FOUNDATION RULES FOR IMPLEMENTING OPEN MEETINGS WITHIN THE INTER-AMERICAN FOUNDATION § 1004.3 Requirement of open meetings. Members shall not jointly conduct or...

22 CFR 1004.3 - Requirement of open meetings.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Requirement of open meetings. 1004.3 Section 1004.3 Foreign Relations INTER-AMERICAN FOUNDATION RULES FOR IMPLEMENTING OPEN MEETINGS WITHIN THE INTER-AMERICAN FOUNDATION § 1004.3 Requirement of open meetings. Members shall not jointly conduct or...

22 CFR 1004.3 - Requirement of open meetings.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Requirement of open meetings. 1004.3 Section 1004.3 Foreign Relations INTER-AMERICAN FOUNDATION RULES FOR IMPLEMENTING OPEN MEETINGS WITHIN THE INTER-AMERICAN FOUNDATION § 1004.3 Requirement of open meetings. Members shall not jointly conduct or...

22 CFR 1004.3 - Requirement of open meetings.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Requirement of open meetings. 1004.3 Section 1004.3 Foreign Relations INTER-AMERICAN FOUNDATION RULES FOR IMPLEMENTING OPEN MEETINGS WITHIN THE INTER-AMERICAN FOUNDATION § 1004.3 Requirement of open meetings. Members shall not jointly conduct or...

22 CFR 1004.3 - Requirement of open meetings.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Requirement of open meetings. 1004.3 Section 1004.3 Foreign Relations INTER-AMERICAN FOUNDATION RULES FOR IMPLEMENTING OPEN MEETINGS WITHIN THE INTER-AMERICAN FOUNDATION § 1004.3 Requirement of open meetings. Members shall not jointly conduct or...

Joint fit of Warm Absorbers in COS and HETG spectra of NGC 3783

NASA Astrophysics Data System (ADS)

Fu, Xiao-Dan; Zhang, Shui-Nai; Sun, Wei; Niu, Shu; Ji, Li

2017-09-01

Warm Absorbers (WAs), as an important form of AGN outflows, show absorption in both the UV and X-ray bands. Using XSTAR generated photoionization models, for the first time we present a joint fit to the simultaneous observations of HST/COS and Chandra/HETG on NGC 3783. A total of five WAs explain well all absorption features from the AGN outflows, which are spread over a wide range of parameters: ionization parameter logξ from 0.6 to 3.8, column density log {N}{{H}} from 19.5 to 22.3 cm-2, velocity v from 380 to 1060 km s-1, and covering factor from 0.33 to 0.75. Not all the five WAs are consistent in pressure. Two of them are likely different parts of the same absorbing gas, and two of the other WAs may be smaller discrete clouds that are blown out from the inner region of the torus at different periods. The five WAs suggest a total mass outflowing rate within the range of 0.22-4.1 solar mass per year.

Effects of joint configuration for the arc welding of cast Ti-6Al-4V alloy rods in argon.

PubMed

Taylor, J C; Hondrum, S O; Prasad, A; Brodersen, C A

1998-03-01

Titanium and its alloys are more commonly used in prosthodontics and welding has become the most common modality for their joining. Studies on the welding of titanium and its alloys have not quantified this value, though its importance has been suggested. This study compared the strength and properties of the joint achieved at various butt joint gaps by the arc-welding of cast Ti-6Al-4V alloy tensile bars in an argon atmosphere. Forty of 50 specimens were sectioned and welded at four gaps. All specimens underwent tensile testing to determine ultimate tensile strength and percentage elongation, then oxygen analysis and scanning electron microscopy. As no more than 3 samples in any group of 10 actually fractured in the weld itself, a secondary analysis that involved fracture location was initiated. There were no differences in ultimate tensile strength or percentage elongation between specimens with weld gaps of 0.25, 0.50, 0.75, and 1.00 mm and the as-cast specimens. There were no differences in ultimate tensile strength between specimens fracturing in the weld and those fracturing in the gauge in welded specimens; however, as-cast specimens demonstrated a higher ultimate tensile strength than welded specimens that fractured in the weld. Specimens that fractured in the weld site demonstrated less ductility than those that fractured in the gauge in both welded and as-cast specimens, as confirmed by scanning electron microscopy examination. The weld wire showed an oxygen scavenging effect from the as-cast parent alloy. The effects of the joint gap were not significant, whereas the characteristics of the joint itself were, which displayed slightly lower strength and significantly lower ductility (and thus decreased toughness). The arc-welding of cast titanium alloy in argon atmosphere appears to be a reliable and efficient prosthodontic laboratory modality producing predictable results, although titanium casting and joining procedures must be closely controlled to

KSC-06pd0688

NASA Image and Video Library

2006-04-20

KENNEDY SPACE CENTER, FLA. -- A mother osprey watches over her chicks in a nest near the NASA News Center at Kennedy Space Center. This is the third year the ospreys have raised a family at the site. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge, which shares a boundary with the Center. Photo credit: NASA/George Shelton

KSC-04pd0901

NASA Image and Video Library

2004-04-20

KENNEDY SPACE CENTER, FLA. - Against the background of the NASA logo on the Vehicle Assembly Building, the osprey nest in the nearby parking lot reveals two fledglings and one of the adult ospreys. Known as a fish hawk, they often can be seen flying overhead with a fish in their talons. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

KSC-04pd0902

NASA Image and Video Library

2004-04-20

KENNEDY SPACE CENTER, FLA. - Against the background of the NASA logo on the Vehicle Assembly Building, the osprey nest in the nearby parking lot reveals two fledglings and one of the adult ospreys. Known as a fish hawk, they often can be seen flying overhead with a fish in their talons. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

KSC-04pd1211

NASA Image and Video Library

2004-05-17

KENNEDY SPACE CENTER, FLA. -- - Two young ospreys flex their wings for flight. Their nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04pd1217

NASA Image and Video Library

2004-05-18

KENNEDY SPACE CENTER, FLA. -- One of the fledgling ospreys from the nest in the NASA KSC News Center parking lot lands on a sign after testing its wings. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04pd1212

NASA Image and Video Library

2004-05-17

KENNEDY SPACE CENTER, FLA. -- One young osprey tests its wings while another waits nearby. Their nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04pd1214

NASA Image and Video Library

2004-05-17

KENNEDY SPACE CENTER, FLA. -- Two fledgling ospreys begin flight lessons with their parent nearby (right). Their nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-0901

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. Against the background of the NASA logo on the Vehicle Assembly Building, the osprey nest in the nearby parking lot reveals two fledglings and one of the adult ospreys. Known as a fish hawk, they often can be seen flying overhead with a fish in their talons. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

KSC-04PD-1211

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- Two young ospreys flex their wings for flight. Their nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-1213

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- An adult osprey hovers over two of its fledglings, perhaps encouraging them to fly. Their nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-1212

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One young osprey tests its wings while another waits nearby. Their nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-1214

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- Two fledgling ospreys begin flight lessons with their parent nearby (right). Their nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-0902

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. Against the background of the NASA logo on the Vehicle Assembly Building, the osprey nest in the nearby parking lot reveals two fledglings and one of the adult ospreys. Known as a fish hawk, they often can be seen flying overhead with a fish in their talons. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

KSC-04PD-1217

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One of the fledgling ospreys from the nest in the NASA KSC News Center parking lot lands on a sign after testing its wings. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

Joint inversion of phase velocity dispersion and H/V ratio curves from seismic noise recordings using a genetic algorithm, considering higher modes

NASA Astrophysics Data System (ADS)

Parolai, S.; Picozzi, M.; Richwalski, S. M.; Milkereit, C.

2005-01-01

Seismic noise contains information on the local S-wave velocity structure, which can be obtained from the phase velocity dispersion curve by means of array measurements. The H/V ratio from single stations also contains information on the average S-wave velocity and the total thickness of the sedimentary cover. A joint inversion of the two data sets therefore might allow constraining the final model well. We propose a scheme that does not require a starting model because of usage of a genetic algorithm. Furthermore, we tested two suitable cost functions for our data set, using a-priori and data driven weighting. The latter one was more appropriate in our case. In addition, we consider the influence of higher modes on the data sets and use a suitable forward modeling procedure. Using real data we show that the joint inversion indeed allows for better fitting the observed data than using the dispersion curve only.

Mechanical properties of welded joints of the reduced-activation ferritic steel: 8% Cr-2% W-0.2% V-0.04% Ta-Fe

NASA Astrophysics Data System (ADS)

Hayakawa, H.; Yoshitake, A.; Tamura, M.; Natsume, S.; Gotoh, A.; Hishinuma, A.

1991-03-01

A reduced-activation ferritic steel, 8Cr-2W-0.2V-0.04Ta-Fe (F-82H) has been developed by JAERI and NKK to improve creep properties and toughness as compared with HT9. The mechanical properties and phase stability of the steel were reported at the previous conferences, ICFRM-2 and 3. This paper is concerned with the mechanical properties of weld metal and welded joints using a newly-developed filler wire of F-82H which contains less C and Ta than the base metal. The design concept of chemical composition of the filler wire was based on as much reduction of activity after irradiation as possible and considerations of the hardenability and toughness of the weld metal. Mechanical properties, such as tensile strength and toughness, of the weld metal and welded joints produced by GTAW after stress-relieving heat treatment were investigated. The results showed that this welding material has almost the same properties as the base metal.

Building a Better Ace: Restructuring The Marine Expeditionary Unit’s Air Combat Elements in the MV-22 ERA

DTIC Science & Technology

2009-01-01

FROM, ABSTRACTION FROM, OR REPRODUCTION OF ALL OR ANY PART OF THIS DOCUMENT IS PERMITTED PROVIDED PROPER ACKNOWLEDGEMENT IS MADE. 1 Executive Summary...aft slash) typically reserved for two CH-53E Super Stallions and all six AV-8B Harriers, and a forward aircraft staging area (forward slash). The...Ospreys, with detachments of four CH-53Es Super Stallions , four AH-lW Cobras, two UH-IN Hueys, and six AV-8B Harriers. This configuration can be

Digital tomosynthesis rendering of joint margins for arthritis assessment

NASA Astrophysics Data System (ADS)

Duryea, Jeffrey W.; Neumann, Gesa; Yoshioka, Hiroshi; Dobbins, James T., III

2004-05-01

PURPOSE: Rheumatoid arthritis (RA) of the hand is a significant healthcare problem. Techniques to accurately quantity the structural changes from RA are crucial for the development and prescription of therapies. Analysis of radiographic joint space width (JSW) is widely used and has demonstrated promise. However, radiography presents a 2D view of the joint. In this study we performed tomosynthesis reconstructions of proximal interphalangeal (PIP), and metacarpophalangeal (MCP) joints to measure the 3D joint structure. METHODS: We performed a reader study using simulated radiographs of 12 MCP and 12 PIP joints from skeletal specimens imaged with micro-CT. The tomosynthesis technique provided images of reconstructed planes with 0.75 mm spacing, which were presented to 2 readers with a computer tool. The readers were instructed to delineate the joint surfaces on tomosynthetic slices where they could visualize the margins. We performed a quantitative analysis of 5 slices surrounding the central portion of each joint. Reader-determined JSW was compared to a gold standard. As a figure of merit we calculated the average root-mean square deviation (RMSD). RESULTS: RMSD was 0.22 mm for both joints. For the individual joints, RMSD was 0.18 mm (MCP), and 0.26 mm (PIP). The reduced performance for the smaller PIP joints suggests that a slice spacing less than 0.75 mm may be more appropriate. CONCLUSIONS: We have demonstrated the capability of limited 3D rendering of joint surfaces using digital tomosynthesis. This technique promises to provide an improved method to visualize the structural changes of RA.

Wing Download Results from a Test of a 0.658-Scale V-22 Rotor and Wing

NASA Technical Reports Server (NTRS)

Felker, Fort F.

1992-01-01

A test of a 0.658-scale V-22 rotor and wing was conducted in the 40 x 80 Foot Wind Tunnel at Ames Research Center. One of the principal objectives of the test was to measure the wing download in hover for a variety of test configurations. The wing download and surface pressures were measured for a wide range of thrust coefficients, with five different flap angles, two nacelle angles, and both directions or rotor rotation. This paper presents these results, and describes a new method for interpreting wing surface pressure data in hover. This method shows that the wing flap can produce substantial lift loads in hover.

Aqueous V(V)-peroxo-amino acid chemistry. Synthesis, structural and spectroscopic characterization of unusual ternary dinuclear tetraperoxo vanadium(V)-glycine complexes.

PubMed

Gabriel, C; Kaliva, M; Venetis, J; Baran, P; Rodriguez-Escudero, I; Voyiatzis, G; Zervou, M; Salifoglou, A

2009-01-19

Vanadium participation in cellular events entails in-depth comprehension of its soluble and bioavailable forms bearing physiological ligands in aqueous distributions of binary and ternary systems. Poised to understand the ternary V(V)-H(2)O(2)-amino acid interactions relevant to that metal ion's biological role, we have launched synthetic efforts involving the physiological ligands glycine and H(2)O(2). In a pH-specific fashion, V(2)O(5), glycine, and H(2)O(2) reacted and afforded the unusual complexes (H(3)O)(2)[V(2)(O)(2)(mu(2):eta(2):eta(1)-O(2))(2)(eta(2)-O(2))(2)(C(2)H(5)NO(2))] x 5/4 H(2)O (1) and K(2)[V(2)(O)(2)(mu(2):eta(2):eta(1)-O(2))(2)(eta(2)-O(2))(2)(C(2)H(5)NO(2))] x H(2)O (2). 1 crystallizes in the triclinic space group P1, with a = 7.805(4) A, b = 8.134(5) A, c = 12.010(7) A, alpha = 72.298(9) degrees, beta = 72.991(9) degrees, gamma = 64.111(9) degrees, V = 641.9(6) A(3), and Z = 2. 2 crystallizes in the triclinic space group P1, with a = 7.6766(9) A, b = 7.9534(9) A, c = 11.7494(13) A, alpha = 71.768(2) degrees, beta = 73.233(2) degrees, gamma = 65.660(2) degrees, V = 610.15(12) A(3), and Z = 2. Both complexes 1 and 2 were characterized by UV/visible, LC-MS, FT-IR, Raman, NMR spectroscopy, cyclic voltammetry, and X-ray crystallography. The structures of 1 and 2 reveal the presence of unusual ternary dinuclear vanadium-tetraperoxo-glycine complexes containing [(V(V)=O)(O(2))(2)](-) units interacting through long V-O bonds and an effective glycinate bridge. The latter ligand is present in the dianionic assembly as a bidentate moiety spanning both V(V) centers in a zwitterionic form. The collective physicochemical properties of the two ternary species 1 and 2 project the chemical role of the low molecular mass biosubstrate glycine in binding V(V)-diperoxo units, thereby stabilizing a dinuclear V(V)-tetraperoxo dianion. Structural comparisons of the anions in 1 and 2 with other known dinuclear V(V)-tetraperoxo binary anionic species provide insight

Effect of joint design and welding type on the flexural strength and weld penetration of Ti-6Al-4V alloy bars.

PubMed

Simamoto Júnior, Paulo Cézar; Resende Novais, Veridiana; Rodrigues Machado, Asbel; Soares, Carlos José; Araújo Raposo, Luís Henrique

2015-05-01

Framework longevity is a key factor for the success of complete-arch prostheses and commonly depends on the welding methods. However, no consensus has been reached on the joint design and welding type for improving framework resistance. The purpose of this study was to assess the effect of different joint designs and welding methods with tungsten inert gas (TIG) or laser to join titanium alloy bars (Ti-6Al-4V). Seventy titanium alloy bar specimens were prepared (3.18 mm in diameter × 40.0 mm in length) and divided into 7 groups (n=10): the C-control group consisting of intact specimens without joints and the remaining 6 groups consisting of specimens sectioned perpendicular to the long-axis and rejoined using an I-, X30-, or X45-shaped joint design with TIG welding (TI, TX30, and TX45) or laser welding (LI, LX30, and LX45). The specimens were tested with 3-point bending. The fracture surfaces were first evaluated with stereomicroscopy to measure the weld penetration area and then analyzed with scanning electron microscopy (SEM). The data were statistically analyzed with 2-way ANOVA and the Tukey post hoc test, 1-way ANOVA and the Dunnett test, and the Pearson correlation test (α=.05). Specimens from the X30 and X45 groups showed higher flexural strength (P<.05) and welded area (P<.05) than specimens from the I groups, regardless of the welding type. TIG welded groups showed significantly higher flexural strength than the laser groups (P<.05), regardless of the joint design. TIG welding also resulted in higher welded areas than laser welding for the I-shaped specimens. No significant differences were found for the weld penetration area in the X45 group, either for laser or TIG welding. SEM analysis showed more pores at the fracture surfaces of the laser specimens. Fracture surfaces indicative of regions of increased ductility were detected for the TIG specimens. TIG welding resulted in higher flexural strength for the joined titanium specimens than laser welding

Effects of Fabrication Parameters on Interface of Zirconia and Ti-6Al-4V Joints Using Zr55Cu30Al10Ni5 Amorphous Filler

NASA Astrophysics Data System (ADS)

Liu, Yuhua; Hu, Jiandong; Shen, Ping; Guo, Zuoxing; Liu, Huijie

2013-09-01

ZrO2 was brazed to Ti-6Al-4V using a Zr55Cu30Al10Ni5 (at.%) amorphous filler in a high vacuum at 1173-1273 K. The influences of brazing temperature, holding time, and cooling rate on the microstructure and shear strength of the joints were investigated. The interfacial microstructures can be characterized as ZrO2/ZrO2- x + TiO/(Zr,Ti)2(Cu,Ni)/(Zr,Ti)2(Cu,Ni,Al)/acicular Widmanstäten structure/Ti-6Al-4V. With the increase in the brazing temperature, both the thickness of the ZrO2- x + TiO layer and the content of the (Zr,Ti)2(Cu,Ni) phase decreased. However, the acicular Widmanstäten structure gradually increased. With the increase in the holding time, the (Zr,Ti)2(Cu,Ni) phase decreased, and the thickness of the (Zr,Ti)2(Cu,Ni) + (Zr,Ti)2(Cu,Ni,Al) layer decreased. In addition, cracks formed adjacent to the ZrO2 side under rapid cooling. The microstructures produced under various fabrication parameters directly influence the shear strength of the joints. When ZrO2 and Ti-6Al-4V couples were brazed at 1173 K for 10 min and then cooled at a rate of 5 K/min, the maximum shear strength of 95 MPa was obtained.

Fluoroscopic Sacroiliac Joint Injection: Is Oblique Angulation Really Necessary?

PubMed

Khuba, Sandeep; Agarwal, Anil; Gautam, Sujeet; Kumar, Sanjay

2016-01-01

The conventional technique for sacroiliac (SI) joint injection involves aligning the anterior and posterior aspects of the SI joint under fluoroscopic guidance and then entering the SI joint in the most caudal aspect. We wish to highlight that there is no added advantage to aligning both the anterior and posterior joint lines of the SI joint as it is time consuming, associated with additional radiation exposure, and may make the entry into the posterior SI joint technically more difficult. Observational study. Pain Clinic, Department of Anesthesiology. With the patient lying prone on fluoroscopy table, SI joint injection is performed with a 22 G, 10 cm spinal needle in a true anteroposterior (AP) view, where anterior and posterior SI joint spaces are seen as separate entities, where the medial joint space represents the posterior SI joint and the lateral joint space represents the anterior SI joint. The distal 1 cm of the medial joint space is entered under AP view. If the SI joint is seen as a straight line rather than 2 joint spaces in the AP view then the image intensifier of the fluoroscope was tilted cranially to elongate the image of the lower part of the posterior SI joint, thus facilitating entry into this part of the joint which was confirmed by administering 0.3 to 0.5 mL of radiopaque contrast medium. Sixty SI joints of 58 patients were injected under an AP fluoroscopic view. Forty-two (70%) SI joints were seen as 2 separate medial and lateral joint spaces and were entered in distal 1 cm of the medial joint space. In 18 (30%) joints seen as a straight line rather than 2 separate spaces, the image intensifier of the fluoroscope was tilted cranially to elongate the image of the lower part of the posterior SI joint and then the SI joint was entered in its distal 1 cm. Confirmation of entry into the SI joint was confirmed by with 0.3 to 0.5 mL of radiopaque contrast medium. In 4 cases the joints did not show the correct radiopaque contrast spread (3/42 and 1

KSC-04pd1147

NASA Image and Video Library

2004-05-14

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings exercises its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04pd1146

NASA Image and Video Library

2004-05-14

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings exercises its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04pd0953

NASA Image and Video Library

2004-04-21

KENNEDY SPACE CENTER, FLA. - Against the backdrop of the American flag, painted on the side of the Vehicle Assembly Building, an osprey checks its fledglings in the nest. The young bird seen is one of three hatched this season. The osprey nest sits atop a speaker in the parking lot of the NASA KSC News Center. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

KSC-04pd1144

NASA Image and Video Library

2004-05-14

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings spreads its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04pd1145

NASA Image and Video Library

2004-05-14

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings spreads its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04pd1218

NASA Image and Video Library

2004-05-18

KENNEDY SPACE CENTER, FLA. -- One of the fledgling ospreys from the nest in the NASA KSC News Center parking lot comes down for a rough landing in the nearby grass. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04pd1215

NASA Image and Video Library

2004-05-18

KENNEDY SPACE CENTER, FLA. -- One of two fledgling ospreys still in the nest stretches its wings to fly away. The stick-built nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-1145

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings spreads its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04PD-1146

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings exercises its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04PD-1147

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings exercises its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04PD-1218

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One of the fledgling ospreys from the nest in the NASA KSC News Center parking lot comes down for a rough landing in the nearby grass. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-1144

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One of three osprey fledglings spreads its wings, anticipating flight. The nest is in the NASA News Center parking lot, across from the Vehicle Assembly Building, with its 209-foot-high American flag painted on the south side. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons.

KSC-04PD-1215

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. -- One of two fledgling ospreys still in the nest stretches its wings to fly away. The stick-built nest is located in the NASA KSC News Center parking lot. Ospreys select nesting sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge. Known as a fish hawk, ospreys often can be seen flying overhead with a fish in their talons. Fish are their sole source of food.

KSC-04PD-0953

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. Against the backdrop of the American flag, painted on the side of the Vehicle Assembly Building, an osprey checks its fledglings in the nest. The young bird seen is one of three hatched this season. The osprey nest sits atop a speaker in the parking lot of the NASA KSC News Center. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

22 CFR 401.25 - Government brief regarding navigable waters.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Government brief regarding navigable waters. 401.25 Section 401.25 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE Applications § 401.25 Government brief regarding navigable waters. When in the opinion of the...

Results of Operative and Nonoperative Treatment of Rockwood Types III and V Acromioclavicular Joint Dislocation

PubMed Central

Joukainen, Antti; Kröger, Heikki; Niemitukia, Lea; Mäkelä, E. Antero; Väätäinen, Urho

2014-01-01

Background: The optimal treatment of acute, complete dislocation of the acromioclavicular joint (ACJ) is still unresolved. Purpose: To determine the difference between operative and nonoperative treatment in acute Rockwood types III and V ACJ dislocation. Study Design: Randomized controlled trial; Level of evidence, 2. Methods: In the operative treatment group, the ACJ was reduced and fixed with 2 transarticular Kirschner wires and ACJ ligament suturing. The Kirschner wires were extracted after 6 weeks. Nonoperatively treated patients received a reduction splint for 4 weeks. At the 18- to 20-year follow-up, the Constant, University of California at Los Angeles Shoulder Rating Scale (UCLA), Larsen, and Simple Shoulder Test (SST) scores were obtained, and clinical and radiographic examinations of both shoulders were performed. Results: Twenty-five of 35 potential patients were examined at the 18- to 20-year follow-up. There were 11 patients with Rockwood type III and 14 with type V dislocations. Delayed surgical treatment for ACJ was used in 2 patients during follow-up: 1 in the operatively treated group and 1 in the nonoperatively treated group. Clinically, ACJs were statistically significantly less prominent or unstable in the operative group than in the nonoperative group (normal/prominent/unstable: 9/4/3 and 0/6/3, respectively; P = .02) and in the operative type III (P = .03) but not type V dislocation groups. In operatively and nonoperatively treated patients, the mean Constant scores were 83 and 85, UCLA scores 25 and 27, Larsen scores 11 and 11, and SST scores 11 and 12 at follow-up, respectively. There were no statistically significant differences in type III and type V dislocations. In the radiographic analysis, the ACJ was wider in the nonoperative than the operative group (8.3 vs 3.4 mm; P = .004), and in the type V dislocations (nonoperative vs operative: 8.5 vs 2.4 mm; P = .007). There was no statistically significant difference between study groups in

Empirical Assessment of the Mean Block Volume of Rock Masses Intersected by Four Joint Sets

NASA Astrophysics Data System (ADS)

Morelli, Gian Luca

2016-05-01

The estimation of a representative value for the rock block volume ( V b) is of huge interest in rock engineering in regards to rock mass characterization purposes. However, while mathematical relationships to precisely estimate this parameter from the spacing of joints can be found in literature for rock masses intersected by three dominant joint sets, corresponding relationships do not actually exist when more than three sets occur. In these cases, a consistent assessment of V b can only be achieved by directly measuring the dimensions of several representative natural rock blocks in the field or by means of more sophisticated 3D numerical modeling approaches. However, Palmström's empirical relationship based on the volumetric joint count J v and on a block shape factor β is commonly used in the practice, although strictly valid only for rock masses intersected by three joint sets. Starting from these considerations, the present paper is primarily intended to investigate the reliability of a set of empirical relationships linking the block volume with the indexes most commonly used to characterize the degree of jointing in a rock mass (i.e. the J v and the mean value of the joint set spacings) specifically applicable to rock masses intersected by four sets of persistent discontinuities. Based on the analysis of artificial 3D block assemblies generated using the software AutoCAD, the most accurate best-fit regression has been found between the mean block volume (V_{{{{b}}_{{m}} }}) of tested rock mass samples and the geometric mean value of the spacings of the joint sets delimiting blocks; thus, indicating this mean value as a promising parameter for the preliminary characterization of the block size. Tests on field outcrops have demonstrated that the proposed empirical methodology has the potential of predicting the mean block volume of multiple-set jointed rock masses with an acceptable accuracy for common uses in most practical rock engineering applications.

Time-Spectral Rotorcraft Simulations on Overset Grids

NASA Technical Reports Server (NTRS)

Leffell, Joshua I.; Murman, Scott M.; Pulliam, Thomas H.

2014-01-01

The Time-Spectral method is derived as a Fourier collocation scheme and applied to NASA's overset Reynolds-averaged Navier-Stokes (RANS) solver OVERFLOW. The paper outlines the Time-Spectral OVERFLOWimplementation. Successful low-speed laminar plunging NACA 0012 airfoil simulations demonstrate the capability of the Time-Spectral method to resolve the highly-vortical wakes typical of more expensive three-dimensional rotorcraft configurations. Dealiasing, in the form of spectral vanishing viscosity (SVV), facilitates the convergence of Time-Spectral calculations of high-frequency flows. Finally, simulations of the isolated V-22 Osprey tiltrotor for both hover and forward (edgewise) flight validate the three-dimensional Time-Spectral OVERFLOW implementation. The Time-Spectral hover simulation matches the time-accurate calculation using a single harmonic. Significantly more temporal modes and SVV are required to accurately compute the forward flight case because of its more active, high-frequency wake.

Relationship Between the Range of Motion and Isometric Strength of Elbow and Shoulder Joints and Ball Velocity in Women Team Handball Players.

PubMed

Schwesig, René; Hermassi, Souhail; Wagner, Herbert; Fischer, David; Fieseler, Georg; Molitor, Thomas; Delank, Karl-Stefan

2016-12-01

Schwesig, R, Hermassi, S, Wagner, H, Fischer, D, Fieseler, G, Molitor, T, and Delank, K-S. Relationship between the range of motion and isometric strength of elbow and shoulder joints and ball velocity in women team handball players. J Strength Cond Res 30(12): 3428-3435, 2016-The aims of this study were to investigate relationships between isometric strength and range of motion (ROM) of shoulder and elbow joints and compare 2 different team handball throwing techniques in women team handball. Twenty highly experienced women team handball players (age: 20.7 ± 2.9 years; body mass: 68.4 ± 6.0 kg; and height: 1.74 ± 0.06 m) participated in this study. The isometric strength (hand-held dynamometer) and ROM (goniometer) of shoulder and elbow joints were measured at the beginning of the preseasonal training. After clinical examination, the subjects performed 3 standing throws with run-up (10 m) and 3 jump throws over a hurdle (0.20 m). The mean ball velocity was calculated from 3 attempts and measured using a radar gun. The results showed that the ball velocity of the standing throw with run-up (vST) was significantly higher than that of the jump throw (vJT) (25.5 ± 1.56 vs. 23.2 ± 1.31 m·s; p < 0.001). Therefore, significant playing position effects (p = 0.021) were only found for ST. Goalkeepers (n = 2) had the lowest (22.6 ± 0.04 m·s) and backcourt players (n = 9), the highest (26.1 ± 1.36 m·s) vST. The retroversion strength in the shoulder was the only parameter with relevant correlations to both throws (vST: r = 0.52, and vJT: r = 0.43). Other relevant relationships to vJT were found for adduction strength shoulder (r = 0.55) and ROM flexion elbow (r = -0.54). The vST was only correlated to the glenohumeral internal rotation deficit. As a consequence, strength is more important than the ROM, and in addition to this, the shoulder, compared with the elbow, has a greater influence on the vST in highly experienced women team handball players.

Studying the properties and response of a large volume (946 cm3) LaBr3:Ce detector with γ-rays up to 22.5 MeV

NASA Astrophysics Data System (ADS)

Mazumdar, I.; Gothe, D. A.; Anil Kumar, G.; Yadav, N.; Chavan, P. B.; Patel, S. M.

2013-03-01

This paper presents the results of our measurements and detailed simulations using GEANT4 to investigate the performance of a large volume (946 cm3) cylindrical (3.5 in.diameter×6 in.length) LaBr3:Ce detector. The properties of the detector have been studied using γ-rays from radioactive sources and in-beam reaction, from few hundred keV to 22.5 MeV. The salient features, which have been studied in-depth, are the uniformity and internal activity of the crystal, the energy and timing resolutions, linearity of the response up to 22.5 MeV, and efficiencies. A highly linear response has been observed by extracting the energy signal from a lower dynode and operating the PMT at a low voltage. The detector is to be primarily used for measuring high energy γ-rays spectra from Giant Dipole Resonance (GDR) decay studies.

22 CFR 401.8 - Decision by the whole Commission.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Decision by the whole Commission. 401.8 Section 401.8 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE... matter or question which the Treaty or any other treaty or international agreement, either in terms or by...

Evaluation of pipe-type cable joint restraint systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Silver, D.A.; Seman, G.W.

1990-03-01

the purpose of this project was to evaluate two systems for restraining the movement of 345kV high-pressure oil-filled (HPOF) cable joints during load cycling. Problems with joints and adjacent cables due to thermomechanical bending (TMB) experienced by the Consolidated Edison Company of New York and Public Service Electric Gas Company of New Jersey are reviewed. Some approaches to reducing or preventing TMB induced damage to HPOF pipe type cable joints are discussed. The design and operation of a special test apparatus for simulating TMB effects under laboratory conditions is described. One of the two joint restraint systems evaluated under thismore » project was developed by PSE G and employed wedging devices, which could be retrofitted into existing installations, that limited the longitudinal movement of the joints during load cycling. The other system developed by Pirelli Cable Corporation applied the restraining force to the cylindrical portion of the hand applied joint insulation by means of support spiders and steel rods attached to the reducer faces. The test results show that the PSE G restraint system can effectively limit joint longitudinal movement while causing a minimal amount of mechanical disturbance to the joint stress cones. The test results obtained with the PCC system are inconclusive and indicate that further refinement and testing are required to demonstrate the effectiveness of this promising joint restraint system.« less

Phosphatase inhibition augments anti-CD22-mediated signaling and cytotoxicity in non-hodgkin's lymphoma cells.

PubMed

O'Donnell, Robert T; Pearson, David; McKnight, Hayes C; Ma, Ya Peng; Tuscano, Joseph M

2009-07-01

CD22 is a cell-surface molecule found on most B-cell lymphomas (NHL). HB22.7 is an anti-CD22 antibody that blocks CD22 ligand binding, initiates signaling, and kills NHL cells. The SHP-1 tyrosine phosphatase is disproportionately associated with the cytoplasmic domain of CD22. Sodium orthovanadate (NaV) and dephostatin (DP) are phosphatase inhibitors. The interaction of SHP-1 with CD22 presents an opportunity to manipulate CD22-mediated signaling effects. NaV caused dose dependent killing of NHL cells in vitro; when HB22.7 was given with NaV, antibody-mediated cell death increased. NaV caused a substantial increase in CD22-mediated SAPK and ERK-1/2 activation when CD22 was crosslinked by HB22.7; NaV did not significantly affect IgM-mediated signals. Studies using Raji NHL cells stably transfected with a SHP-1 dominant negative (DN) confirmed that these observations were due to SHP-1 inhibition. The relatively specific association of SHP-1 with CD22 suggests that CD22-specific signaling may be altered by phosphatase inhibition in ways that could prove useful for anti-CD22-based immunotherapy.

Multireference quantum chemistry through a joint density matrix renormalization group and canonical transformation theory.

PubMed

Yanai, Takeshi; Kurashige, Yuki; Neuscamman, Eric; Chan, Garnet Kin-Lic

2010-01-14

We describe the joint application of the density matrix renormalization group and canonical transformation theory to multireference quantum chemistry. The density matrix renormalization group provides the ability to describe static correlation in large active spaces, while the canonical transformation theory provides a high-order description of the dynamic correlation effects. We demonstrate the joint theory in two benchmark systems designed to test the dynamic and static correlation capabilities of the methods, namely, (i) total correlation energies in long polyenes and (ii) the isomerization curve of the [Cu(2)O(2)](2+) core. The largest complete active spaces and atomic orbital basis sets treated by the joint DMRG-CT theory in these systems correspond to a (24e,24o) active space and 268 atomic orbitals in the polyenes and a (28e,32o) active space and 278 atomic orbitals in [Cu(2)O(2)](2+).

Joint in-flight portrait of the STS-81 and Mir 22 crew on Mir

NASA Image and Video Library

1997-02-26

STS081-369-003 (12-22 Jan. 1997) --- Traditional inflight crew portrait of the combined Mir-22 and STS-81 crews in the Base Block Module aboard Russia's Mir Space Station. Front row: left to right, Michael A. Baker, commander; John M. Grunsfeld, mission specialist; and cosmonaut Aleksandr Y. Kaleri, Mir-22 flight engineer. Middle row: cosmonaut Valeri G. Korzun, Mir-22 commander; Marsha S. Ivins, mission specialist; and John E. Blaha, former cosmonaut guest researcher. Back row: Jerry M. Linenger, cosmonaut guest researcher; Peter J. K. (Jeff) Wisoff, mission specialist; and Brent W. Jett, Jr., pilot. Linenger is seen in a Russian jump suit, and Blaha now wears a Space Shuttle inflight garment as the two exchanged cosmonaut guest researcher roles on January 14, 1997, following the docking of the Atlantis and the Mir complex.

High-resolution ultrasonography in assessing temporomandibular joint disc position.

PubMed

Talmaceanu, Daniel; Lenghel, Lavinia Manuela; Bolog, Nicolae; Popa Stanila, Roxana; Buduru, Smaranda; Leucuta, Daniel Corneliu; Rotar, Horatiu; Baciut, Mihaela; Baciut, Grigore

2018-02-04

The purpose of this study was to determine the diagnostic value of high-resolution ultrasonography (US) in temporomandibular joint (TMJ) disc displacements. A number of 74 patients (148 TMJs) with signs and symptoms of TMJ disorders, according to the Research Diagnostic Criteria for Temporomandibular Disorders, were included in this study. All patients received US and magnetic resonance imaging (MRI) of both TMJs 1 to 5 days after the clinical examination. MRI examinations were performed using 1.5 T MRI equipment (Siemens Avanto, Siemens, Erlangen). Ultrasonographic examination was performed on a Hitachi EUB 8500 (Hitachi Medical Corp., Tokyo, Japan) scanner with L 54 M6.5-13 MHz linear transducer. MRI depicted 68 (45.95%) normal joints, 47 (31.76%) with disc displacement with reduction, 33 (22.3%) with disc displacement without reduction and 34 (22.97%) with degenerative changes. US detected 78 (52.7%) normal joints, 37 (25%) with disc displacement with reduction, 33 (22.3%) with disc displacement without reduction and 21 (14.19%) with degenerative changes. Compared to MRI, US showed a sensitivity of 93.1%, specificity of 87.88%, accuracy of 90.32%, a positive predictive value of 87.1% and a negative predictive value of 93.55% for overall diagnosis of disc displacement. The Youden index was 0.81. Based on our results, high-resolution ultrasonography showed high sensitivity, specificity and accuracy in the diagnosis of TMJ disc displacement. It could be a valuable imaging technique in assessing TMJ disc position. The diagnostic value of high-resolution ultrasonography depends strictly on the examiner's skills and on the equipment used.

19 CFR 356.22 - Prehearing conference.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 3 2011-04-01 2011-04-01 false Prehearing conference. 356.22 Section 356.22 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE PROCEDURES AND RULES FOR...) Settlement of the matter; (iv) Discovery; and (v) Such other matters as may expedite the disposition of the...

19 CFR 356.22 - Prehearing conference.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 3 2012-04-01 2012-04-01 false Prehearing conference. 356.22 Section 356.22 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE PROCEDURES AND RULES FOR...) Settlement of the matter; (iv) Discovery; and (v) Such other matters as may expedite the disposition of the...

19 CFR 356.22 - Prehearing conference.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Prehearing conference. 356.22 Section 356.22 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE PROCEDURES AND RULES FOR...) Settlement of the matter; (iv) Discovery; and (v) Such other matters as may expedite the disposition of the...

19 CFR 356.22 - Prehearing conference.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Prehearing conference. 356.22 Section 356.22 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE PROCEDURES AND RULES FOR...) Settlement of the matter; (iv) Discovery; and (v) Such other matters as may expedite the disposition of the...

19 CFR 356.22 - Prehearing conference.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 3 2014-04-01 2014-04-01 false Prehearing conference. 356.22 Section 356.22 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE PROCEDURES AND RULES FOR...) Settlement of the matter; (iv) Discovery; and (v) Such other matters as may expedite the disposition of the...

22 CFR 401.9 - Suspension or amendment of rules.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Suspension or amendment of rules. 401.9 Section 401.9 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.9 Suspension or amendment of rules. The commission may suspend, repeal, or amend all or any...

The Treatment of Joint Pain with Intra-articular Pulsed Radiofrequency.

PubMed

Schianchi, Pietro M; Sluijter, Menno E; Balogh, Susan E

2013-09-01

The intra-articular (IA) application of pulsed radiofrequency (PRF) for pain in small and large joints represents a recent development that has proven to be effective in many cases. We performed a retrospective study of 89 such procedures in 57 consecutive patients with chronic articular pain. The aim of this retrospective study is to evaluate the effectiveness of intraarticular PRF in a group of 57 consecutive patients with chronic joint pain. Patients with intractable joint pain for more than 6 months were treated with IA PRF 40-45V for 10-15 min in small joints and 60V for 15 min in large joints using fluoroscopic confirmation of correct needle position. A total of 28 shoulders, 40 knees, 10 trapezio-metacarpal, and 11 first metatarso-phalangeal joints were treated. Results were evaluated at 1, 2, and 5 months. The procedure was repeated after 1 month in 10 patients with initial suboptimal results. Success was defined as a reduction of pain score by at least 50%. All groups showed significant reductions in pain scores at all three follow-up visits. Success rates were higher in small joints (90% and 82%, respectively) than large ones (64% and 60%, respectively). Interestingly, IA PRF was successful in 6 out of 10 patients who had undergone previous surgery, including 3 with prosthetic joint replacement and in 6 of the 10 repeated procedures. There were no significant adverse effects or complications. IA PRF induced significant pain relief of long duration in a majority of our patients with joint pain. The exact mechanism is unclear, but may be related to the exposure of immune cells to low-strength RF fields, inducing an anti-inflammatory effect. The success rate appears to be highest in small joints. We recommend additional research including control groups to further investigate and clarify this method; our data suggest that it may represent a useful modality in the treatment of arthrogenic pain.

Taiwan: Major U.S. Arms Sales Since 1990

DTIC Science & Technology

2013-07-03

amphibious assault vehicles; AN/ALE-50 electronic countermeasure (ECM) systems for F-16s; and 12 MH-53 mine -sweeping helicopters. President Bush...235 Commercial sale. Opall Barbara and David Silverberg, “Taiwanese May Soon Coproduce Patriot,” Defense News, February 22-28...systems) $340 01/29 (2) Osprey-class mine hunting ships (refurbished and upgraded) $105 2011 09/21 Retrofit of 145 F-16A/B fighters, with 176 AESA

Thermal Fatigue Study of W/cu Joint

NASA Astrophysics Data System (ADS)

Zhang, Fu; Wu, Jihong; Xu, Zengyu; Xu, Ying

2003-06-01

HHFC mock-ups with a structure of W/Cu/SS were developed by hot isostatic pressing (HIP). The performance of the W/Cu joint under high heat loads was tested using an electron beam. The size of specimens for heat load tests was 25×25 mm and the size of beam spot on the specimen surface was 22 mm in diameter. During heat load test, the specimens were water-cooled. Thermal fatigue test were conducted at power density of 8.7 MW/m2 with pulse duration of 20 seconds and interval of 20 seconds. After 1000 cycles of tests, no cracks and failure were found in the W/Cu joint. The thermal performance was also investigated in the range of 1 ~ 9 MW/m2.

Joint awareness in osteoarthritis of the hip and knee evaluated with the 'Forgotten Joint' Score before and after joint replacement.

PubMed

Thienpont, E; Vanden Berghe, A; Schwab, P E; Forthomme, J P; Cornu, O

2016-10-01

To utilize the 'Forgotten Joint' Score (FJS), a 12-item questionnaire analysing the ability to forget the joint, for comparing preoperative status in osteoarthritic patients scheduled for total hip arthroplasty (THA) or total knee arthroplasty (TKA). Higher scores represent a better result with a maximum of 100. The hypothesis of this study was that a preoperative difference in favour of hip arthritis could eventually explain why THA is cited more often as a forgotten joint than TKA. A prospective cohort study was conducted in 150 patients with either tricompartmental knee (n = 75) or hip osteoarthritis (n = 75). Patients completed FJS-12 scores preoperatively and 1 year postoperatively. A similar preoperative FJS-12 was observed for hip (22 (15)) and knee osteoarthritis (24 (17)) (n.s.). The postoperative FJS-12 score was significantly higher for THA (80 (24)) than for TKA (70 (27)) (p < 0.05). High reliability after 6 weeks was observed for the preoperative FJS-12 test-retest reliability (ICC = 0.87) in TKA. A preoperative floor effect of 15 % in THA and 0 % in TKA was found as well as a postoperative ceiling effect of 33 % in THA and 9 % in TKA. The clinical relevance of utilizing the FJS-12 as an instrument to evaluate outcome is strongly proposed for knee arthroplasty. In general, one is not aware of a healthy joint during the ADL, and it can therefore be regarded as 'forgotten'. The preoperative FJS-12 Score is a powerful tool to provide patients with clearer insights into their positive evolution after surgery. The use of the FJS-12 in THA is a topic for further research, as this study found that floor and ceiling effects limit its usefulness in studies evaluating clinical outcome in this area. II.

Reduced heat input keyhole welding through improved joint design

NASA Technical Reports Server (NTRS)

Sanders, John M. (Inventor); Harwig, Dennis D. (Inventor)

1993-01-01

An improved high energy density welding method for reducing input keyhole welding prepares the weld joint (8) between two edges (10, 14) of at least one member by separating the edges (10, 14) of the member (12, 16) with a controllable gap (22) by a projecting portion (24) selectively positioned on one edge (10, 14) of the member (12, 16). The projecting portion (24) closely abuts the other edge of the member for maintaining the controlled distance (d) of the controllable gap (22) to enhance the welding method.

KSC-04pd0879

NASA Image and Video Library

2004-04-16

KENNEDY SPACE CENTER, FLA. - Two fledgling ospreys occupy a nest near the NASA-KSC News Center, across from the Vehicle Assembly Building. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

22 CFR 401.18 - Supplemental or amended applications and statements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... application, statement in response or statement in reply, as the case may be, to be presented. (b) Where... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Supplemental or amended applications and statements. 401.18 Section 401.18 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA...

22. INTERIOR VIEW OF TYPICAL OIL TANK, PORT SIDE, LOOKING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. INTERIOR VIEW OF TYPICAL OIL TANK, PORT SIDE, LOOKING FORWARD. NOTE SHIP'S FRAMING MEMBERS AND UNIVERSAL JOINT IN SHAFT FOR PUMPING VALVE AT BOTTOM OF TANK. THE ACCESS LADDER STEPS ARE MARKED WITH LEVEL INDICATIONS. - Ship "Falls of Clyde", Hawaii Maritime Center, Pier 7, Honolulu, Honolulu County, HI

Comparison of Tensile Damage Evolution in Ti6A14V Joints Between Laser Beam Welding and Gas Tungsten Arc Welding

NASA Astrophysics Data System (ADS)

Gao, Xiao-Long; Zhang, Lin-Jie; Liu, Jing; Zhang, Jian-Xun

2014-12-01

The present paper studied the evolution of tensile damage in joints welded using laser beam welding (LBW) and gas tungsten arc welding (TIG) under a uniaxial tensile load. The damage evolution in the LBW joints and TIG-welded joints was studied by using digital image correlation (DIC) technology and monitoring changes in Young's modulus during tensile testing. To study the mechanism of void nucleation and growth in the LBW joints and TIG-welded joints, test specimens with various amounts of plastic deformation were analyzed using a scanning electron microscope (SEM). Compared with TIG-welded joints, LBW-welded joints have a finer microstructure and higher microhardness in the fusion zone. The SEM analysis and DIC test results indicated that the critical strain of void nucleation was greater in the LBW-welded joints than in the TIG-welded joints, while the growth rate of voids was lower in the LBW-welded joints than in the TIG-welded joints. Thus, the damage ratio in the LBW joints was lower than that in the TIG-welded joints during tensile testing. This can be due to the coarser martensitic α' and the application of TC-1 welding rods in the TIG-welded joint.

WASP-167b/KELT-13b: joint discovery of a hot Jupiter transiting a rapidly rotating F1V star

NASA Astrophysics Data System (ADS)

Temple, L. Y.; Hellier, C.; Albrow, M. D.; Anderson, D. R.; Bayliss, D.; Beatty, T. G.; Bieryla, A.; Brown, D. J. A.; Cargile, P. A.; Collier Cameron, A.; Collins, K. A.; Colón, K. D.; Curtis, I. A.; D'Ago, G.; Delrez, L.; Eastman, J.; Gaudi, B. S.; Gillon, M.; Gregorio, J.; James, D.; Jehin, E.; Joner, M. D.; Kielkopf, J. F.; Kuhn, R. B.; Labadie-Bartz, J.; Latham, D. W.; Lendl, M.; Lund, M. B.; Malpas, A. L.; Maxted, P. F. L.; Myers, G.; Oberst, T. E.; Pepe, F.; Pepper, J.; Pollacco, D.; Queloz, D.; Rodriguez, J. E.; Ségransan, D.; Siverd, R. J.; Smalley, B.; Stassun, K. G.; Stevens, D. J.; Stockdale, C.; Tan, T. G.; Triaud, A. H. M. J.; Udry, S.; Villanueva, S.; West, R. G.; Zhou, G.

2017-11-01

We report the joint WASP/KELT discovery of WASP-167b/KELT-13b, a transiting hot Jupiter with a 2.02-d orbit around a V = 10.5, F1V star with [Fe/H] = 0.1 ± 0.1. The 1.5 RJup planet was confirmed by Doppler tomography of the stellar line profiles during transit. We place a limit of <8 MJup on its mass. The planet is in a retrograde orbit with a sky-projected spin-orbit angle of λ = -165° ± 5°. This is in agreement with the known tendency for orbits around hotter stars to be more likely to be misaligned. WASP-167/KELT-13 is one of the few systems where the stellar rotation period is less than the planetary orbital period. We find evidence of non-radial stellar pulsations in the host star, making it a δ-Scuti or γ-Dor variable. The similarity to WASP-33, a previously known hot-Jupiter host with pulsations, adds to the suggestion that close-in planets might be able to excite stellar pulsations.

Systems engineering in a joint program environment: the joint helmet-mounted cueing system

NASA Astrophysics Data System (ADS)

Wilkins, Donald F.

1999-07-01

The Joint Helmet Mounted Cueing System (JHMCS) is a design program involving two airframe companies (Boeing and Lockheed Martin), two services (USAF and USN) and four aircraft platforms: the F-22, the F-16, the F/A-18 and the F-15. Developing equipment requirements for the combined operational and environmental needs of these diverse communities is a significant challenge. In addition, the team is geographically dispersed which presented challenges in communication and coordination. This paper details the lessons learned in producing a cost-effective design within a short development schedule and makes recommendations for future development programs.

Future Operating Concept - Joint Computer Network Operations

DTIC Science & Technology

2010-02-17

into the system‖ at a later date by circumventing the need for access privileges 3. Cyberwarfare Tools 67 • Social Engineering • Hacking ...Forces Command, Joint Operating Environment 2008, November 2008https://us.jfcom.mil/sites/ J5 /j59/default.aspx VIII Appendix V

Multibody Kinematics Optimization for the Estimation of Upper and Lower Limb Human Joint Kinematics: A Systematized Methodological Review.

PubMed

Begon, Mickaël; Andersen, Michael Skipper; Dumas, Raphaël

2018-03-01

Multibody kinematics optimization (MKO) aims to reduce soft tissue artefact (STA) and is a key step in musculoskeletal modeling. The objective of this review was to identify the numerical methods, their validation and performance for the estimation of the human joint kinematics using MKO. Seventy-four papers were extracted from a systematized search in five databases and cross-referencing. Model-derived kinematics were obtained using either constrained optimization or Kalman filtering to minimize the difference between measured (i.e., by skin markers, electromagnetic or inertial sensors) and model-derived positions and/or orientations. While hinge, universal, and spherical joints prevail, advanced models (e.g., parallel and four-bar mechanisms, elastic joint) have been introduced, mainly for the knee and shoulder joints. Models and methods were evaluated using: (i) simulated data based, however, on oversimplified STA and joint models; (ii) reconstruction residual errors, ranging from 4 mm to 40 mm; (iii) sensitivity analyses which highlighted the effect (up to 36 deg and 12 mm) of model geometrical parameters, joint models, and computational methods; (iv) comparison with other approaches (i.e., single body kinematics optimization and nonoptimized kinematics); (v) repeatability studies that showed low intra- and inter-observer variability; and (vi) validation against ground-truth bone kinematics (with errors between 1 deg and 22 deg for tibiofemoral rotations and between 3 deg and 10 deg for glenohumeral rotations). Moreover, MKO was applied to various movements (e.g., walking, running, arm elevation). Additional validations, especially for the upper limb, should be undertaken and we recommend a more systematic approach for the evaluation of MKO. In addition, further model development, scaling, and personalization methods are required to better estimate the secondary degrees-of-freedom (DoF).

Distraction for proximal interphalangeal joint contractures: long-term results.

PubMed

Houshian, Shirzad; Jing, Shan Shan; Kazemian, Gholam Hussein; Emami-Moghaddam-Tehrani, Mohammad

2013-10-01

To report the medium- to long-term outcomes of joint distraction using a unilateral external fixator in the treatment of chronic post-traumatic proximal interphalangaeal (PIP) joint contractures. Between September 2001 and October 2011, 94 consecutive patients (98 PIP joints) with a mean age of 43 years (range, 17-69 y) were treated with external fixation for chronic flexion deformity of the PIP joint from trauma. The average time from injury to surgery was 48 months (range, 6-84 mo), and the duration of joint distraction was 10 days (range, 7-22 d). Patients were followed for a mean period of 54 months (range, 12-72 mo). The average gain in joint flexion was 25° and in joint extension was 40°. The mean improvement in the active range of movement was 67° (range. 30°-90°). There was no loss of motion on the latest follow-up. Patients younger than 40 years fared slightly better than those older than 40 years. Two patients developed swelling, pain, and erythema during treatment, which resolved upon temporarily stopping the distraction process. There were 12 cases of superficial pin-site infections, which were managed conservatively without serious complications or adverse outcome. External fixation is a simple and effective treatment modality for chronic traumatic PIP joint contractures with good predictable medium- to long-term results. Careful patient selection and monitoring are required. Copyright © 2013 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

Photodisintegration cross section of the reaction (4)He(γ,p)(3)H between 22 and 30 MeV.

PubMed

Raut, R; Tornow, W; Ahmed, M W; Crowell, A S; Kelley, J H; Rusev, G; Stave, S C; Tonchev, A P

2012-01-27

The two-body photodisintegration cross section of (4)He into a proton and triton was measured with monoenergetic photon beams in 0.5 MeV energy steps between 22 and 30 MeV. High-pressure (4)He-Xe gas scintillators of various (4)He/Xe ratios served as targets and detectors. Pure Xe gas scintillators were used for background studies. A NaI detector together with a plastic scintillator paddle was employed for determining the incident photon flux. Our comprehensive data set follows the trend of the theoretical calculations of the Trento group very well, although our data are consistently lower in magnitude by about 5%. However, they differ significantly from the majority of the previous data, especially from the recent data of Shima et al. The latter data had put into question the validity of theoretical approaches used to calculate core-collapse supernova explosions and big-bang nucleosynthesis abundances of certain light nuclei.

ISHKS joint registry: A preliminary report.

PubMed

Pachore, Jawahir A; Vaidya, Shrinand V; Thakkar, Chandrasekhar J; Bhalodia, Haresh Kumar P; Wakankar, Hemant M

2013-09-01

Total knee arthroplasty (TKA) and total hip arthroplasty (THA) are the most widely practiced surgical options for arthritis all over the world and its application is rising in India. Indian Society of Hip and Knee Surgeons (ISHKS) has established a joints registry and has been collecting data for last 6 years. All members of ISHKS are encouraged to actively participate in the registry. A simple two page knee and hip form can be downloaded from the website www.ishks.com. The information collected includes patient demographics, indication for surgery, implant details and in case of revision arthroplasty: the details of implants removed and the cause of failure of primary arthroplasty. These forms are mailed to the central registry office and the data is fed in computerized registry. Data collection started in October 2006. Joint registry is a very important initiative of ISHKS and till date, have data of 34,478 TKAs and 3604 THAs, contributed by 42 surgeons across India. Some important observations have emerged. Data of 34,478 TKAs was assessed: These included 8612 males (25%) and 25,866 females (75%). Average age was 64.4 years (Osteoarthritis range: 45 to 88 years; Rheumatoid arthritis range: 22 to 74 years). Average body mass index was 29.1 (Range: 18.1 to 42.9). The indication for TKA was osteoarthritis in 33,444 (97%) and rheumatoid arthritis in 759 (2.2%). Total of 3604 THA procedures were recorded. These included 2162 (60%) male patients and 1442 (40%) female patients. Average age was 52 years (Range 17 to 85 years) and average BMI was 25.8 (Range: 17.3 to 38.5). The indications for THA was AVN in 49%. The registry will become more meaningful in years to come. Active participation of all arthroplasty surgeons across India is vital for the success of the joints registry.

[Perioperative management in outpatient arthroscopy of the knee joint].

PubMed

Müller-Rath, R; Ingenhoven, E; Mumme, T; Schumacher, M; Miltner, O

2010-05-01

Nowadays, complex arthroscopic procedures of the knee joint, such as ACL reconstruction, are routinely carried out on an outpatient basis. The reduced time spent with the patient places high demands on the surgeon with regard to the management of such cases. The aim of this study was to evaluate the current standards of perioperative management following outpatient arthroscopic surgery of the knee in Germany. A questionnaire consisting of 18 questions was sent to 215 members of the German Association of Outpatient Arthroscopy (BVASK e. V.), dealing with the following topics: antibiotic prophylaxis, DVT prophylaxis, use of a tourniquet and suction drain, physical therapy, physiotherapy, analgesia, anaesthesia and emergency management. More than 51% of the forms were returned and considered suitable for statistical analysis. A total of 62% of the surgeons reported the use of an antibiotic prophylaxis (i. v. single shot) in every arthroscopic case, while 19% administer antibiotics only occasionally, especially in ACL reconstruction. Postoperative antibiotic treatment was reserved for special situations, such as prior joint infection. Prophylaxis of DVT by means of low molecular weight heparin was carried out in 96% of the cases. 51% prescribed anticoagulant agents for 1 week, 39% for the duration of reduced weight bearing. Half of the surgeons used a tourniquet cuff, 22% exsanguinate the limb prior to cuff inflation. A suction drainage was applied by 36% of the surgeons regularly and by 45% occasionally. The drain is left for one day by 79% of the surgeons, while 11% reported a shortened use of only several hours. With regard to analgesia, 66% of all surgeons apply some kind of local anaesthetic into the knee joint post surgery. Systemic preoperative analgesics or anti-inflammatory agents are given regularly in 56 % of the cases. A total of 92% of the procedures are carried out under general anaesthesia. In 36% of the cases, some kind of additional regional peripheral

Management of lumbar zygapophysial (facet) joint pain

PubMed Central

Manchikanti, Laxmaiah; Hirsch, Joshua A; Falco, Frank JE; Boswell, Mark V

2016-01-01

AIM: To investigate the diagnostic validity and therapeutic value of lumbar facet joint interventions in managing chronic low back pain. METHODS: The review process applied systematic evidence-based assessment methodology of controlled trials of diagnostic validity and randomized controlled trials of therapeutic efficacy. Inclusion criteria encompassed all facet joint interventions performed in a controlled fashion. The pain relief of greater than 50% was the outcome measure for diagnostic accuracy assessment of the controlled studies with ability to perform previously painful movements, whereas, for randomized controlled therapeutic efficacy studies, the primary outcome was significant pain relief and the secondary outcome was a positive change in functional status. For the inclusion of the diagnostic controlled studies, all studies must have utilized either placebo controlled facet joint blocks or comparative local anesthetic blocks. In assessing therapeutic interventions, short-term and long-term reliefs were defined as either up to 6 mo or greater than 6 mo of relief. The literature search was extensive utilizing various types of electronic search media including PubMed from 1966 onwards, Cochrane library, National Guideline Clearinghouse, clinicaltrials.gov, along with other sources including previous systematic reviews, non-indexed journals, and abstracts until March 2015. Each manuscript included in the assessment was assessed for methodologic quality or risk of bias assessment utilizing the Quality Appraisal of Reliability Studies checklist for diagnostic interventions, and Cochrane review criteria and the Interventional Pain Management Techniques - Quality Appraisal of Reliability and Risk of Bias Assessment tool for therapeutic interventions. Evidence based on the review of the systematic assessment of controlled studies was graded utilizing a modified schema of qualitative evidence with best evidence synthesis, variable from level I to level V

KSC00pp0969

NASA Image and Video Library

2000-06-07

Angy Chambers, senior wildlife biologist for Environmental Support Contract/Dynamac, holds a juvenile osprey before releasing it at Cape Canaveral Air Force Station. As a nestling, the osprey fell twice from its nest, located on a light pole in the ITL area of CCAFS. Chambers determined the bird might have a broken leg and gave it to the Florida Wildlife Hospital for treatment. The osprey was released the same day as the two great horned owls

KSC-00pp0969

NASA Image and Video Library

2000-06-07

Angy Chambers, senior wildlife biologist for Environmental Support Contract/Dynamac, holds a juvenile osprey before releasing it at Cape Canaveral Air Force Station. As a nestling, the osprey fell twice from its nest, located on a light pole in the ITL area of CCAFS. Chambers determined the bird might have a broken leg and gave it to the Florida Wildlife Hospital for treatment. The osprey was released the same day as the two great horned owls

Association between isometric muscle strength and gait joint kinetics in adolescents and young adults with cerebral palsy.

PubMed

Dallmeijer, A J; Baker, R; Dodd, K J; Taylor, N F

2011-03-01

The purpose of this study was to determine the association between isometric muscle strength of the lower limbs and gait joint kinetics in adolescents and young adults with cerebral palsy (CP). Twenty-five participants (11 males) with bilateral spastic CP, aged 14-22 years (mean: 18.9, sd: 2.0 yr) and Gross Motor Function Classification System (GMFCS) level II (n=19) and III (n=6) were tested. Hand held dynamometry was used to measure isometric strength (expressed in Nm/kg) of the hip, knee, and ankle muscles using standardized testing positions and procedures. 3D gait analysis was performed with a VICON system to calculate joint kinetics in the hip, knee and ankle during gait. Ankle peak moments exceeded by far the levels of isometric strength of the plantar flexors, while the knee and hip peak moments were just at or below maximal isometric strength of knee and hip muscles. Isometric muscle strength showed weak to moderate correlations with peak ankle and hip extension moment and power during walking. Despite considerable muscle weakness, joint moment curves were similar to norm values. Results suggest that passive stretch of the muscle-tendon complex of the triceps surae contributes to the ankle moment during walking and that muscle strength assessment may provide additional information to gait kinetics. Copyright © 2010 Elsevier B.V. All rights reserved.

Characterization of a 2 × 2 array of large square bars of LaBr3:Ce detectors with γ-rays up to 22.5 MeV

NASA Astrophysics Data System (ADS)

Dhibar, M.; Mazumdar, I.; Chavan, P. B.; Patel, S. M.; Anil Kumar, G.

2018-03-01

LaBr3:Ce scintillators have recently become commercially available in sizes large enough for measurements of high energy gamma-rays. In this communication, we report our studies on properties and response of large volume square bars (2‧‧ ×2‧‧ ×8‧‧) of LaBr3:Ce detectors, individually, and in a compact array of four square bars, with gamma-rays up to 22.5 MeV. The properties studied are, uniformity of the crystal, internal radioactivity, energy resolution, timing resolution, linearity of the response and detection efficiencies. The response of the detectors for 22.5 MeV γ-rays produced from 11B(p , γ)12C capture reaction and for 15.1 MeV γ-rays produced from 12C(p ,p‧ γ)12C inelastic scattering reaction are studied in detail. The measured absolute efficiencies (both total detection and photo-peak) for 662 keV gamma-rays from 137Cs are compared to those obtained using realistic GEANT4 simulations. The primary aim of the array is to measure high energy gamma-rays (5-50 MeV) produced from the de-excitation of excited Giant Dipole Resonance (GDR) states, radiative capture reactions, nuclear Bremsstrahlung process and inelastic scattering process. The highly satisfactory performance of the array provides the impetus for future efforts toward building a bigger array.

A comparison of radiation damage in liner ICs from cobalt-60 gamma rays and 2.2-MeV electrons

NASA Technical Reports Server (NTRS)

Gauthier, M. K.; Nichols, D. K.

1983-01-01

The total ionizing dose response of fourteen IC types from eight manufacturers was measured using Co-60 gamma rays and 2.2-MeV electrons for exposure levels of 100 to 20,000 Gy(Si). Key parameter measurements were made and compared for each device type. The data show that a Co-60 source is not a suitable simulation source for some systems because of the generally more damaging nature of electrons as well as the unpredictable nature of the individual device response to the two types of radiations used here.

Taiwan: Major U.S. Arms Sales Since 1990

DTIC Science & Technology

2013-11-27

systems for F-16s; and 12 MH-53 mine -sweeping helicopters. President Bush approved four decommissioned Kidd-class destroyers for sale as Excess Defense...239 Commercial sale. Opall Barbara and David Silverberg, “Taiwanese May Soon Coproduce Patriot,” Defense News, February 22-28...340 01/29 (2) Osprey-class mine hunting ships (refurbished and upgraded) $105 2011 09/21 Retrofit of 145 F-16A/B fighters, with 176 AESA radars

Multivariate Analysis of High Through-Put Adhesively Bonded Single Lap Joints: Experimental and Workflow Protocols

DTIC Science & Technology

2016-06-01

unlimited. v List of Tables Table 1 Single-lap-joint experimental parameters ..............................................7 Table 2 Survey ...Joints: Experimental and Workflow Protocols by Robert E Jensen, Daniel C DeSchepper, and David P Flanagan Approved for...TR-7696 ● JUNE 2016 US Army Research Laboratory Multivariate Analysis of High Through-Put Adhesively Bonded Single Lap Joints: Experimental

77 FR 29749 - Twelfth Meeting: RTCA Special Committee 217, Joint with EUROCAE WG-44, Terrain and Airport...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-18

... Committee 217, Joint with EUROCAE WG-44, Terrain and Airport Mapping Databases AGENCY: Federal Aviation... 217, Joint with EUROCAE WG-44, Terrain and Airport Mapping Databases. SUMMARY: The FAA is issuing this..., Terrain and Airport Mapping Databases. DATES: The meeting will be held June 18-22, 2012, from 9:00 a.m.-5...

Transducer Joint for Kidney-Stone Ultrasonics

NASA Technical Reports Server (NTRS)

Angulo, E. D.

1983-01-01

Ultrasonic therapy for kidney stones improved by new way of connecting wire-probe ultrasonic waveguide to transducer. Improved mounting allows joint to last long enough for effective treatment. Sheath and rubber dampers constrain lateral vibration of wire waveguide. Combination of V-shaped mounting groove, sheath, and rubber dampers increases life expectancy of wire 15 times or more.

Mortality and morbidity associated with gunshot in raptorial birds from the province of Quebec: 1986 to 2007

PubMed Central

Desmarchelier, Marion; Santamaria-Bouvier, Ariane; Fitzgérald, Guy; Lair, Stéphane

2010-01-01

Although raptors have been protected for decades in Quebec they are still regular victims of poaching. The objective of this study was to characterize cases of raptor shootings in Quebec over the last 2 decades. We reviewed clinical files, radiographs, and pathology reports on 4805 free-flying birds of prey admitted to the Faculté de médecine vétérinaire between 1986 and 2007. Evidence of gunshots was detected in 6.4% of the birds. Large species, such as ospreys, turkey vultures, snowy owls, and bald eagles represented the most frequently targeted species. The percentage of shot birds has decreased from 13.4% during 1991 to 1992 to 2.2% in 2006 to 2007. Potential reasons for this trend include a decrease in the presence of firearms in raptor habitats and changes in human attitude towards raptorial birds. PMID:20357944

47 CFR 22.972 - Interference resolution procedures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 2 2012-10-01 2012-10-01 false Interference resolution procedures. 22.972... than February 22, 2005. (3) Cellular Radiotelephone licensees must respond to the initial notification... knowledge or belief after due diligence; (iv) Is not proffered by a contractor or other third party; and (v...

47 CFR 22.972 - Interference resolution procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false Interference resolution procedures. 22.972... than February 22, 2005. (3) Cellular Radiotelephone licensees must respond to the initial notification... knowledge or belief after due diligence; (iv) Is not proffered by a contractor or other third party; and (v...

47 CFR 22.972 - Interference resolution procedures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 2 2013-10-01 2013-10-01 false Interference resolution procedures. 22.972... than February 22, 2005. (3) Cellular Radiotelephone licensees must respond to the initial notification... knowledge or belief after due diligence; (iv) Is not proffered by a contractor or other third party; and (v...

47 CFR 22.972 - Interference resolution procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 47 Telecommunication 2 2014-10-01 2014-10-01 false Interference resolution procedures. 22.972... than February 22, 2005. (3) Cellular Radiotelephone licensees must respond to the initial notification... knowledge or belief after due diligence; (iv) Is not proffered by a contractor or other third party; and (v...

Decrease in local volumetric bone mineral density (vBMD) in osteoarthritic joints is associated with the increase in cartilage damage: a pQCT study

NASA Astrophysics Data System (ADS)

Tamaddon, Maryam; Chen, Shen Mao; Vanaclocha, Leyre; Hart, Alister; El-Husseiny, Moataz; Henckel, Johann; Liu, Chaozong

2017-11-01

Osteoarthritis (OA) is the most common type of arthritis and a major cause of disability in the adult population. It affects both cartilage and subchondral bone in the joints. There has been some progress in understanding the changes in subchondral bone with progression of osteoarthritis. However, local changes in subchondral bone such as microstructure or volumetric bone mineral density in connection with the defect in cartilage are relatively unexplored. To develop an effective treatment for progression of OA, it is important to understand how the physical environment provided by the subchondral bone affects the overlying cartilage. In this study we examined the volumetric bone mineral density (vBMD) distribution in the osteoarthritic joint tissues obtained from total hip replacement surgeries due to osteoarthritis, using peripheral quantitative CT (pQCT). It was found that there is a significant decrease in volumetric bone mineral density, which co-localises with the damage in the overlying cartilage. This was not limited to the subchondral bone immediately adjacent to the cartilage defect but continued in the layers below. Bone resorption and cyst formation in the OA tissues were also detected. We observed that the bone surrounding subchondral bone cysts exhibited much higher volumetric bone mineral density than that of the surrounding bones. PQCT was able to detect significant changes in vBMD between OA and non-OA samples, as well as between areas of different cartilage degeneration, which points to its potential as a technique for detection of early OA.

KSC-06pd0846

NASA Image and Video Library

2006-05-17

KENNEDY SPACE CENTER, FLA. -- A baby osprey sits on its nest situated at the top of a pole in the parking lot at the NASA News Center at Kennedy Space Center. Behind the nest can be seen the immense flag painted on the side of the Vehicle Assembly Building. This is the third year the ospreys have raised a family at the News Center. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge, which shares a boundary with the Center. Photo credit: NASA/George Shelton

[Significance of the glenoid labrum for stability of the glenohumeral joint. An experimental study].

PubMed

Habermeyer, P; Schuller, U

1990-01-01

In human cadavers we were able to show that the glenohumeral joint is comparable to the model of a physical piston. The labrum glenoidale functions like a valve against atmospheric pressure. It is possible to characterize the behavior of intraarticular negative pressure by the equation (formula; see text). The calculations of the force F of atmospheric pressure tending to resist distraction of the joint surfaces leads to a 95% confidence interval from 6.9 to 22.9 kp. Under a general anesthetic, distraction of the healthy glenohumeral joint also produces negative intraarticular pressure in the area of the fossa glenoidalis in vivo. Joints with a labral tear (Bankart defect) and a chronic instability are not characterized by this phenomenon. A change in intraarticular pressure might stimulate intraarticular pressure receptors. This could be important in functioning as a neuromuscular protection reflex for the joint.

Quantification of dynamic posterior translation in modified bilateral Alexander views and correlation with clinical and radiological parameters in patients with acute acromioclavicular joint instability.

PubMed

Minkus, Marvin; Hann, Carmen; Scheibel, Markus; Kraus, Natascha

2017-06-01

Classification of AC-joint instability is based on radiologic evaluation of anteroposterior (a.p.) stress views of both shoulders, neglecting the horizontal component of instability. Recent studies have proposed an association of dynamic posterior translation (DPT) and inferior clinical results. The purpose of this study was to quantify DPT in modified Alexander views and correlate it with other radiological and clinical data. Thirty-two patients (4 f, 28 m, mean age 34.1) with acute AC-joint dislocation (16 = RW III, 16 = RW V) underwent radiological examination including bilateral a.p. stress views with measurement of the coracoclavicular distance (CCD) and bilateral modified Alexander views with different approaches to quantify DPT (overlapping area OA AC , overlapping length OL AC ). In addition, the Constant Score, Subjective Shoulder Value, Taft Score (TF), and the Acromioclavicular Joint Instability Score (ACJI) were obtained. In Rockwood (RW) type III injuries, a mean CCD of 15.8 (9.8-22.8) mm, OA AC of 50.9 (0-216.6) mm 2 , and OL AC of 6.5 (-4.7-17.9) mm were found. RW V patients showed a CCD of 23.1 (13.7-32.0) mm; OA AC 7.0 (0-92.3) mm 2 ; and OL AC -4.8 (-19.6-9.8) mm. Particularly in RW III the CCD, OA AC and OL AC revealed significant correlation with the ACJI (r = -0.64/r = 0.72/r = 0.68, p < 0.05) and TF (r = -0.56/r = 0.68/r = 0.51, p < 0.05). The proposed quantification tools for DPT were found to have a moderate-to-strong correlation with the score results, especially with AC-joint specific scores. RW type V injuries had a moderate correlation with clinical parameters (OA AC with ACJI: r = 0.44, p > 0.05 and OL AC with TF: r = -0.45, p > 0.05). Measuring the OL AC is a convenient way for quantifying DPT in modified Alexander views. It showed significant correlation with clinical scores, indicating the relevance of DPT in patients with AC-joint injury.

Excitation functions for 7Be, 22,24Na production in Mg and Al by deuteron irradiations up to 50 MeV.

PubMed

Hermanne, A; Takács, S; Tárkányi, F; Adam-Rebeles, R; Ignatyuk, A

2012-12-01

New experimental data for production of (7)Be and (22,24)Na in deuteron irradiation of (nat)Mg and Al up to 50 MeV are presented. The induced activity, measured with HPGe spectroscopy, allows us to determine excitation functions of (nat)Mg(d,x) and (27)Al(d,x) reactions involved in the activation process with reference to (nat)Ti(d,x)(48)V monitor cross sections. A comparison with experimental literature values and results from updated theoretical codes is discussed. Thick target yields were derived from fits to our cross-sections and integrated personnel dose was calculated for different irradiation cycles and exposure scenarios around high power deuteron accelerator facilities. Copyright © 2012 Elsevier Ltd. All rights reserved.

Prosthetic elbow joint

NASA Technical Reports Server (NTRS)

Weddendorf, Bruce C. (Inventor)

1994-01-01

An artificial, manually positionable elbow joint for use in an upper extremity, above-elbow, prosthetic is described. The prosthesis provides a locking feature that is easily controlled by the wearer. The instant elbow joint is very strong and durable enough to withstand the repeated heavy loadings encountered by a wearer who works in an industrial, construction, farming, or similar environment. The elbow joint of the present invention comprises a turntable, a frame, a forearm, and a locking assembly. The frame generally includes a housing for the locking assembly and two protruding ears. The forearm includes an elongated beam having a cup-shaped cylindrical member at one end and a locking wheel having a plurality of holes along a circular arc on its other end with a central bore for pivotal attachment to the protruding ears of the frame. The locking assembly includes a collar having a central opening with a plurality of internal grooves, a plurality of internal cam members each having a chamfered surface at one end and a V-shaped slot at its other end; an elongated locking pin having a crown wheel with cam surfaces and locking lugs secured thereto; two coiled compression springs; and a flexible filament attached to one end of the elongated locking pin and extending from the locking assembly for extending and retracting the locking pin into the holes in the locking wheel to permit selective adjustment of the forearm relative to the frame. In use, the turntable is affixed to the upper arm part of the prosthetic in the conventional manner, and the cup-shaped cylindrical member on one end of the forearm is affixed to the forearm piece of the prosthetic in the conventional manner. The elbow joint is easily adjusted and locked between maximum flex and extended positions.

Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype.

PubMed

Grosch, Melanie; Grüner, Barbara; Spranger, Stephanie; Stütz, Adrian M; Rausch, Tobias; Korbel, Jan O; Seelow, Dominik; Nürnberg, Peter; Sticht, Heinrich; Lausch, Ekkehart; Zabel, Bernhard; Winterpacht, Andreas; Tagariello, Andreas

2013-01-01

Spondyloepimetaphyseal dysplasia with joint laxity-leptodactylic type (SEMDJL2) is an autosomal dominant skeletal dysplasia which is characterized by midface hypoplasia, short stature, joint laxity with dislocations, genua valga, progressive scoliosis, and slender fingers. Recently, heterozygous missense mutations in KIF22, a gene which encodes a member of the kinesin-like protein family, have been identified in sporadic as well as familial cases of SEMDJL2. In the present study homozygosity mapping and whole-exome sequencing were combined to analyze a consanguineous family with a phenotype resembling SEMDJL2. We identified homozygous missense mutations in the two nearby genes NIN (Ninein) and POLE2 (DNA polymerase epsilon subunit B) which segregate with the disease in the family and were not present in 500 healthy control individuals and in the 1094 control individuals contained within the 1000-genomes database. We present several lines of evidence that mutant Ninein is most likely causative for the SEMDJL2-like phenotype. The centrosomal protein NIN shows a functional relationship with KIF22 and other proteins associated with chromosome congression/movement, centrosomal function, and ciliogenesis, which have been associated with skeletal dysplasias. Moreover, compound heterozygous missense mutations at more N-terminal positions of Ninein have very recently been identified in a family with microcephalic primordial dwarfism. Together with the present report this strongly supports a fundamental role of Ninein in skeletal development. Copyright © 2013 International Society of Matrix Biology. Published by Elsevier B.V. All rights reserved.

KSC-04pd0952

NASA Image and Video Library

2004-04-21

KENNEDY SPACE CENTER, FLA. - An osprey likes the view atop this American flag, which flies near the NASA KSC News Center. It’s nest is located atop a speaker in the parking lot. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

Toxicological studies on pipemidic acid. V. Effect on diarthrodial joints of experimental animals.

PubMed

Tatsumi, H; Senda, H; Yatera, S; Takemoto, Y; Yamayoshi, M; Ohnishi, K

1978-11-01

Pipemidic acid (PPA) orally given in a dose of 100 mg/kg/day or more was found to cause lame gait in immature beagle dogs of about 3 months old. Their diarthrodial joints were abnormal with increased synovial fluid and blister formation under the outer layer of the articular cartilage. However, such an abnormality was not found in dogs younger than 2 weeks or older than 12 months. The blisters were formed at the joint areas bearing the body weight at a time when PPA was considered to be present there. Nalidixic and piromidic acids, structural analogues of PPA, also caused abnormality similar to PPA. The severity of the arthropathy was slight with piromidic acid as compared with PPA and nalidixic acid. The gait abnormality was almost disappeared spontaneously even if medication was continued. The incidence of the arthropathy was not or rarely observed in any young rats, rabbits and monkeys.

Thickness Distribution of Glenohumeral Joint Cartilage.

PubMed

Schleich, Christoph; Bittersohl, Bernd; Antoch, Gerald; Krauspe, Rüdiger; Zilkens, Christoph; Kircher, Jörn

2017-04-01

High-resolution 3-dimensional cartilage-specific magnetic resonance imaging (MRI) was performed at 3 T to test the following hypotheses: (1) there is a nonuniform cartilage thickness distribution both on the proximal humerus and on the glenoid surface and (2) the glenohumeral joint as a combined system is congruent with the level of the joint cartilage surface without substantial radial mismatch. Inclusion of 38 volunteers (19 females, mean age 24.34 ± 2.22 years; range 21-29 years) in a prospective study. Measurements of: cartilage thickness in 3 regions and 3 zones; radius of both circles (glenoid and humeral cartilage) for congruency calculation using 3-T MRI with 3-dimensional dual-echo steady-state sequence with water excitation. A homogenous mean cartilage thickness (1.2-1.5 mm) and slightly higher values for the glenoidal articulating surface radii both in the mid-paracoronar section (2.4 vs. 2.1 cm, P < 0.001) and in the mid-paraaxial section (2.4 vs. 2.1 cm, P < 0.001) compared with the humeral side were observed. The concept of a radial mismatch between the humeral head and the glenoid in healthy human subjects can be confirmed. This study provides normative data for the comparison of joint cartilage changes at the shoulder for future studies.

Optimised robot-based system for the exploration of elastic joint properties.

PubMed

Frey, M; Burgkart, R; Regenfelder, F; Riener, R

2004-09-01

Numerous publications provide measured biomechanical data relating to synovial joints. However, in general, they do not reflect the non-linear elastic joint properties in detail or do not consider all degrees of freedom (DOF), or the quantity of data is sparse. To perform more comprehensive, extended measurements of elastic joint properties, an optimised robot-based approach was developed. The basis was an industrial, high-precision robot that was capable of applying loads to the joint and measuring the joint displacement in 6 DOF. The system was equipped with novel, custom-made control hardware. In contrast to the commonly used sampling rates that are below 100 Hz, a rate of 4 kHz was realised for each DOF. This made it possible to implement advanced, highly dynamic, quasi-continuous closed-loop controllers. Thus oscillations of the robot were avoided, and measurements were speeded up. The stiffness of the entire system was greater than 44 kNm(-1) and 22 Nm deg(-1), and the maximum difference between two successive measurements was less than 0.5 deg. A sophisticated CT-based referencing routine facilitated the matching of kinematic data with the individual anatomy of the tested joint. The detailed detection of the elastic varus-valgus properties of a human knee joint is described, and the need for high spatial resolution is demonstrated.

Space nuclear system expansion joints

NASA Technical Reports Server (NTRS)

Whitaker, W. D.; Shimazki, T. T.

1973-01-01

The engineering, design, and fabrication status of the expansion joint unit (EJU) to be employed in the NaK primary coolant piping loop of the 5-kwe Reactor thermoelectric system are described. Four EJU's are needed in the NaK primary coolant piping loop. The four EJU's which will be identical, utilize bellows as the flexing member, are hermetically sealed, and provide double containment. The bellows are of a nested-formed design, and are to be constructed of 1-ply thickness of 0.010-in. Inconel 718. The EJU's provide a minimum piping load margin of safety of +0.22.

7. 'FLOW IN CANAL NO. 1, A JOINTLY USED CANAL, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. 'FLOW IN CANAL NO. 1, A JOINTLY USED CANAL, ON MAY 22 WHEN 210 SECOND FEET OF WATER WAS FLOWING. THIS WAS LATER INCREASED TO 240 SECOND FEET FOR A NUMBER OF DAYS TO SATISFY THE DEMANDS OF THE DRY GULCH COMPANY.' 1925 - Irrigation Canals in the Uinta Basin, Duchesne, Duchesne County, UT

Seismicity and structure of Akutan and Makushin Volcanoes, Alaska, using joint body and surface wave tomography

DOE PAGES

Syracuse, E. M.; Maceira, M.; Zhang, H.; ...

2015-02-18

Joint inversions of seismic data recover models that simultaneously fit multiple constraints while playing upon the strengths of each data type. Here, we jointly invert 14 years of local earthquake body wave arrival times from the Alaska Volcano Observatory catalog and Rayleigh wave dispersion curves based upon ambient noise measurements for local V p, V s, and hypocentral locations at Akutan and Makushin Volcanoes using a new joint inversion algorithm.The velocity structure and relocated seismicity of both volcanoes are significantly more complex than many other volcanoes studied using similar techniques. Seismicity is distributed among several areas beneath or beyond themore » flanks of both volcanoes, illuminating a variety of volcanic and tectonic features. The velocity structures of the two volcanoes are exemplified by the presence of narrow high-V p features in the near surface, indicating likely current or remnant pathways of magma to the surface. A single broad low-V p region beneath each volcano is slightly offset from each summit and centered at approximately 7 km depth, indicating a potential magma chamber, where magma is stored over longer time periods. Differing recovery capabilities of the Vp and Vs datasets indicate that the results of these types of joint inversions must be interpreted carefully.« less

High-precision Q EC -value measurement of the superallowed β + emitter Mg 22 and an ab initio evaluation of the A = 22 isobaric triplet

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reiter, M. P.; Leach, K. G.; Drozdowski, O. M.

The direct atomic mass difference between 22Mg and 22Na was measured using TRIUMF's Ion Trap for Atomic and Nuclear Science (TITAN) and was determined to be Q=4781.40(22) keV. This measurement represents the most precise single measurement of this quantity to date.

High-precision Q EC -value measurement of the superallowed β + emitter Mg 22 and an ab initio evaluation of the A = 22 isobaric triplet

DOE PAGES

Reiter, M. P.; Leach, K. G.; Drozdowski, O. M.; ...

2017-11-06

The direct atomic mass difference between 22Mg and 22Na was measured using TRIUMF's Ion Trap for Atomic and Nuclear Science (TITAN) and was determined to be Q=4781.40(22) keV. This measurement represents the most precise single measurement of this quantity to date.

Tumours of bones and joints

PubMed Central

Misdorp, W.; Van Der Heul, R. O.

1976-01-01

Tumours of bones and joints are not infrequent in dogs but are rare in other domestic animals. In the dog, most bone tumours are malignant; osteosarcomas are by far the most frequently encountered tumours, especially in giant breeds and boxers. The following main categories of bone tumour are described: bone-forming, cartilage-forming, giant cell, marrow, vascular, miscellaneous, metastatic, unclassified, and tumour-like lesions. The tumours of joints and related structures are classified as synovial sarcomas, fibroxanthomas, and malignant giant cell tumour of soft tissues. ImagesFig. 21Fig. 22Fig. 23Fig. 24Fig. 17Fig. 18Fig. 19Fig. 20Fig. 29Fig. 30Fig. 31Fig. 32Fig. 33Fig. 34Fig. 35Fig. 36Fig. 25Fig. 26Fig. 27Fig. 28Fig. 1Fig. 2Fig. 3Fig. 4Fig. 37Fig. 38Fig. 39Fig. 40Fig. 5Fig. 6Fig. 7Fig. 8Fig. 13Fig. 14Fig. 15Fig. 16Fig. 9Fig. 10Fig. 11Fig. 12 PMID:1086157

Construction of testing facilities and verifying tests of a 22.9 kV/630 A class superconducting fault current limiter

NASA Astrophysics Data System (ADS)

Yim, S.-W.; Yu, S.-D.; Kim, H.-R.; Kim, M.-J.; Park, C.-R.; Yang, S.-E.; Kim, W.-S.; Hyun, O.-B.; Sim, J.; Park, K.-B.; Oh, I.-S.

2010-11-01

We have constructed and completed the preparation for a long-term operation test of a superconducting fault current limiter (SFCL) in a Korea Electric Power Corporation (KEPCO) test grid. The SFCL with rating of 22.9 kV/630 A, 3-phases, has been connected to the 22.9 kV test grid equipped with reclosers and other protection devices in Gochang Power Testing Center of KEPCO. The main goals of the test are the verification of SFCL performance and protection coordination studies. A line-commutation type SFCL was fabricated and installed for this project, and the superconducting components were cooled by a cryo-cooler to 77 K in the sub-cooled liquid nitrogen pressurized by 3 bar of helium gas. The verification test includes un-manned - long-term operation with and without loads and fault tests. Since the test site is 170 km away from the laboratory, we will adopt the un-manned operation with real-time remote monitoring and controlling using high speed internet. For the fault tests, we will apply fault currents up to around 8 kArms to the SFCL using an artificial fault generator. The fault tests may allow us not only to confirm the current limiting capability of the SFCL, but also to adjust the SFCL - recloser coordination such as resetting over-current relay parameters. This paper describes the construction of the testing facilities and discusses the plans for the verification tests.

KSC-06pd0847

NASA Image and Video Library

2006-05-17

KENNEDY SPACE CENTER, FLA. -- A mother osprey (left) sits protectively next to one of her chicks in the nest situated at the top of a pole in the parking lot at the NASA News Center at Kennedy Space Center. Behind the nest can be seen the immense flag painted on the side of the Vehicle Assembly Building. This is the third year the ospreys have raised a family at the News Center. Known as a fish hawk, ospreys select sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States they are found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge, which shares a boundary with the Center. Photo credit: NASA/George Shelton

Taiwan: Major U.S. Arms Sales Since 1990

DTIC Science & Technology

2010-08-31

howitzers; 54 AAV7A1 amphibious assault vehicles; AN/ALE-50 electronic countermeasure (ECM) systems for F-16s; and 12 MH-53 mine -sweeping helicopters...268 Commercial sale. Opall Barbara and David Silverberg, “Taiwanese May Soon Coproduce Patriot,” Defense News, February 22-28, 1993; Military...29 (2) Osprey-class mine hunting ships (refurbished and upgraded) $105 Author Contact Information Shirley A. Kan Specialist in Asian Security Affairs skan@crs.loc.gov, 7-7606

Taiwan: Major U.S. Arms Sales Since 1990

DTIC Science & Technology

2012-02-24

howitzers; 54 AAV7A1 amphibious assault vehicles; AN/ALE-50 electronic countermeasure (ECM) systems for F-16s; and 12 MH-53 mine -sweeping helicopters...Grimmett. 279 Commercial sale. Opall Barbara and David Silverberg, “Taiwanese May Soon Coproduce Patriot,” Defense News, February 22-28, 1993...Sheng C4 systems) $340 01/29 (2) Osprey-class mine hunting ships (refurbished and upgraded) $105 2011 09/21 Retrofit of 145 F-16A/B fighters, with

Joint SSRTNet/ALS-MES Workshop report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shuh, David; Van Hove, Michel

2001-11-30

This joint workshop brought together experimentalists and theorists interested in synchrotron radiation and highlighted subjects relevant to molecular environmental science (MES). The strong mutual interest between the participants resulted in joint sessions on the first day, followed by more specialized parallel sessions on the second day. Held in conjunction with the Advanced Light Source (ALS) Users' Association Annual Meeting at the Lawrence Berkeley National Laboratory (Berkeley Lab), the Synchrotron Radiation Research Theory Network (SRRTNet) workshop was co-organized by Michel Van Hove (Berkeley Lab and University of California, Davis) and Andrew Canning (Berkeley Lab), while David Shuh (Berkeley Lab) organized themore » ALS-MES workshop. SRRTNet is a global network that promotes the interaction of theory and experiment (http://www.cse.clrc.ac.uk/Activity/SRRTnet). The ALS-MES project is constructing Beamline 11.0.2.1-2, a new soft x-ray beamline for MES investigations at photon energies from 75 eV to 2 keV, to provide photons for wet spectroscopy end stations and an upgraded scanning transmission x-ray microscope (STXM). The ALS-MES beamline and end stations will be available for users in the late fall of 2002.« less

KSC-03pd0775

NASA Image and Video Library

2003-03-19

KENNEDY SPACE CENTER, FLA. - Framed by the NASA insignia, on the outside of the Vehicle Assembly Building, this osprey stares out from the nest it has built on top of speakers in a nearby parking lot. Known as a fish hawk, the osprey selects sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

KSC-03pd0776

NASA Image and Video Library

2003-03-19

KENNEDY SPACE CENTER, Fla. - Framed by the NASA insignia, on the outside of the Vehicle Assembly Building, this osprey stares out from the nest it has built on top of speakers in a nearby parking lot. Known as a fish hawk, the osprey selects sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and nearby Merritt Island National Wildlife Refuge.

Controlling transformations in the assembly of polyoxometalate clusters: {Mo11V7}, {Mo17V8} and {Mo72V30}.

PubMed

Miras, Haralampos N; Ochoa, M Nieves Corella; Long, De-Liang; Cronin, Leroy

2010-11-21

The reaction of molybdate with vanadium(V) in the presence of sulfite anions is explored showing how, via cation control, stepwise assembly through the {Mo(11)V(7)} cluster yields a {M(25)} cluster-based compound, [Mo(VI)(11)V(V)(5)V(IV)(2)O(52)(μ(9)-SO(3))(Mo(VI)(6)V(V)O(22))](10-) (1a), which was first discovered using cryospray mass spectrometry, whereas switching the cation away from ammonium allows the direct formation of the spherical 'Keplerate' {Mo(72)V(30)} cluster.

Joint Technical Coordinating Group on Aircraft Survivability (JTCG/AS). Bibliography of Joint Aircraft Survivability Reports

DTIC Science & Technology

2000-07-01

PMSG ). Report No.: JTCG/AS-99-D-003 Report Classification: UNCLASSIFIED Title: JTCG/AS Bibliography of Joint Aircraft Survivability Reports and...indicates those approved and not approved for funding by the Principal Members Steering Group ( PMSG ). Report No.: Report Classification: JTCG/AS-97-V-010...demonstrated by additional tests conducted at NWSC/Crane (up to Mach 0.8) and Rockwell International wind tunnel (up to Mach 1/9 and 30,000 feet altitude

Effect of long-term aging on microstructure and local behavior in the heat-affected zone of a Ni–Cr–Mo–V steel welded joint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Ming-Liang, E-mail: mlzhu@ecust.edu.cn; Wang, De-Qiang; Xuan, Fu-Zhen

2014-01-15

Evolution of microstructure, micro-hardness and micro-tensile strength behavior was investigated in the heat-affected zone of a Ni–Cr–Mo–V steel welded joint after the artificial aging at 350 °C for 3000 h. After detailed characterization of microstructures in optical microscopy, scanning electron microscopy and transmission electron microscopy, it is revealed that the change of martensite–bainite constituent promotes more homogeneous microstructure distribution. The aging treatment facilitates redistribution of carbon and chromium elements along the welded joint, and the micro-hardness is increased slightly through the welds due to enrichment of carbon. The types of precipitates in the weldment mainly include M{sub 3}C, MC, M{submore » 2}C and M{sub 23}C{sub 6}. The carbides in base metal, weld metal and coarse-grained heat-affected zone are prone to change from ellipsoidal to platelet form whereas more uniform spherical carbides are observed in the fine-grained zone. Precipitation and coarsening of M{sub 23}C{sub 6} near the fusion line, and formation of MC and M{sub 2}C, are responsible for the tensile strength decrease and its smooth distribution in the aged heat-affected zone. This implies that the thermal aging can relieve strength mismatch in the weldments. - Highlights: • Microstructure homogeneity improved in HAZ after long-term aging. • Tensile strength decreased in HAZ due to precipitation and coarsening of M{sub 23}C{sub 6}. • Strength mismatch in NiCrMoV steel welds was relieved after aging at 350 °C × 3000 h.« less

Brief report: High and low level initiations of joint attention, and response to joint attention: differential relationships with language and imitation.

PubMed

Pickard, Katherine E; Ingersoll, Brooke R

2015-01-01

Frequency of high-level (showing/pointing) and low-level (coordinated gaze shifts) behaviors on the Early Social Communication Scales are often used as a measure of joint attention initiations (IJA). This study examined the degree to which these skills and response to joint attention (RJA; e.g. gaze following) were differentially related to measures of language and imitation in 53 children with autism spectrum disorder between the ages of 22 and 93 months. High-level and low-level IJA were not associated with each other, and only high-level IJA was associated with RJA, and language and imitation measures. High-level IJA and RJA were unique predictors of imitation, while RJA was a unique predictor of language. Findings indicate that IJA involves distinct skills, with high-level behaviors more closely related to social-communication skills.

Performance of Pallet Nails and Staples in 22 Southern Hardwoods

Treesearch

E.G. Stern

1976-01-01

The effectiveness of pointless, helically threaded, hardened-steel, 3 by O.120-inch, pallet nails with umbrella heads and 21/2-inch, 15-gauge, 7/16-inch crown, plastic-coated, pallet staples in 22 hardwoods grown on southern pine sites was determined on the basis of tests on 522 joints. Specific average performance values were derived from the test data for the tested...

Determination of alkylphenol and alkylphenolethoxylates in biota by liquid chromatography with detection by tandem mass spectrometry and fluorescence spectroscopy

USGS Publications Warehouse

Schmitz-Afonso, I.; Loyo-Rosales, J.E.; de la Paz Aviles, M.; Rattner, B.A.; Rice, C.P.

2003-01-01

A quantitative method for the simultaneous determination of octylphenol, nonylphenol and the corresponding ethoxylates (1 to 5) in biota is presented. Extraction methods were developed for egg and fish matrices based on accelerated solvent extraction followed by a solid-phase extraction cleanup, using octadecylsilica or aminopropyl cartridges. Identification and quantitation were accomplished by liquid chromatography-electrospray tandem mass spectrometry (LC-MS-MS) and compared to the traditional liquid chromatography with fluorescence spectroscopy detection. LC-MS-MS provides high sensitivity and specificity required for these complex matrices and an accurate quantitation with the use of 13C-labeled internal standards. Quantitation limits by LC-MS-MS ranged from 4 to 12 ng/g in eggs, and from 6 to 22 ng/g in fish samples. These methods were successfully applied to osprey eggs from the Chesapeake Bay and fish from the Great Lakes area. Total levels found in osprey egg samples were up to 18 ng/g wet mass and as high as 8.2 ug/g wet mass in the fish samples.

Analysis of postmarket complaints database for the iFuse SI Joint Fusion System®: a minimally invasive treatment for degenerative sacroiliitis and sacroiliac joint disruption

PubMed Central

Miller, Larry E; Reckling, W Carlton; Block, Jon E

2013-01-01

Background The sacroiliac joint is a common but under-recognized source of low back and gluteal pain. Patients with degenerative sacroiliitis or sacroiliac joint disruption resistant to nonsurgical treatments may undergo open surgery with sacroiliac joint arthrodesis, although outcomes are mixed and risks are significant. Minimally invasive sacroiliac joint arthrodesis was developed to minimize the risk of iatrogenic injury and to improve patient outcomes compared with open surgery. Methods Between April 2009 and January 2013, 5319 patients were treated with the iFuse SI Joint Fusion System® for conditions including sacroiliac joint disruption and degenerative sacroiliitis. A database was prospectively developed to record all complaints reported to the manufacturer in patients treated with the iFuse device. Complaints were collected through spontaneous reporting mechanisms in support of ongoing mandatory postmarket surveillance efforts. Results Complaints were reported in 204 (3.8%) patients treated with the iFuse system. Pain was the most commonly reported clinical complaint (n = 119, 2.2%), with nerve impingement (n = 48, 0.9%) and recurrent sacroiliac joint pain (n = 43, 0.8%) most frequently cited. All other clinical complaints were rare (≤0.2%). Ninety-six revision surgeries were performed in 94 (1.8%) patients at a median follow-up of four (range 0–30) months. Revisions were typically performed in the early postoperative period for treatment of a symptomatic malpositioned implant (n = 46, 0.9%) or to correct an improperly sized implant in an asymptomatic patient (n = 10, 0.2%). Revisions in the late postoperative period were performed to treat symptom recurrence (n = 34, 0.6%) or for continued pain of undetermined etiology (n = 6, 0.1%). Conclusion Analysis of a postmarket product complaints database demonstrates an overall low risk of complaints with the iFuse SI Joint Fusion System in patients with degenerative sacroiliitis or sacroiliac joint

Analysis of postmarket complaints database for the iFuse SI Joint Fusion System®: a minimally invasive treatment for degenerative sacroiliitis and sacroiliac joint disruption.

PubMed

Miller, Larry E; Reckling, W Carlton; Block, Jon E

2013-01-01

The sacroiliac joint is a common but under-recognized source of low back and gluteal pain. Patients with degenerative sacroiliitis or sacroiliac joint disruption resistant to nonsurgical treatments may undergo open surgery with sacroiliac joint arthrodesis, although outcomes are mixed and risks are significant. Minimally invasive sacroiliac joint arthrodesis was developed to minimize the risk of iatrogenic injury and to improve patient outcomes compared with open surgery. Between April 2009 and January 2013, 5319 patients were treated with the iFuse SI Joint Fusion System® for conditions including sacroiliac joint disruption and degenerative sacroiliitis. A database was prospectively developed to record all complaints reported to the manufacturer in patients treated with the iFuse device. Complaints were collected through spontaneous reporting mechanisms in support of ongoing mandatory postmarket surveillance efforts. Complaints were reported in 204 (3.8%) patients treated with the iFuse system. Pain was the most commonly reported clinical complaint (n = 119, 2.2%), with nerve impingement (n = 48, 0.9%) and recurrent sacroiliac joint pain (n = 43, 0.8%) most frequently cited. All other clinical complaints were rare (≤0.2%). Ninety-six revision surgeries were performed in 94 (1.8%) patients at a median follow-up of four (range 0-30) months. Revisions were typically performed in the early postoperative period for treatment of a symptomatic malpositioned implant (n = 46, 0.9%) or to correct an improperly sized implant in an asymptomatic patient (n = 10, 0.2%). Revisions in the late postoperative period were performed to treat symptom recurrence (n = 34, 0.6%) or for continued pain of undetermined etiology (n = 6, 0.1%). Analysis of a postmarket product complaints database demonstrates an overall low risk of complaints with the iFuse SI Joint Fusion System in patients with degenerative sacroiliitis or sacroiliac joint disruption.

Microstructure and Properties of the Ti6Al4V/Inconel 625 Bimetal Obtained by Explosive Joining

NASA Astrophysics Data System (ADS)

Topolski, Krzysztof; Szulc, Zygmunt; Garbacz, Halina

2016-08-01

The study is concerned with the bimetallic plate composed of the Ti6Al4V and Inconel 625 alloys. The alloys were joined together using the explosive method with the aim to produce a bimetallic joint. The structure and the mechanical properties of the as-received raw Ti6Al4V and Inconel 625 alloys, the Ti6Al4V/Inconel 625 joint, and the joint after annealing (600 °C for 1 h) were examined. The samples observations were performed using a light microscope and a scanning electron microscope. The mechanical properties were estimated by microhardness measurements, tensile tests, and three-point bending tests. Moreover, the deformation strengthening of the metals and the strength of the joint were analyzed. The explosive process resulted in a good quality bimetallic joint. Both sheets were deformed plastically and the joint surface between the alloys had a wavy shape. In the area of the joint surface, the hardness was increased. For example, the annealing at 600 °C for 1 h resulted in changes of the microhardness in the entire volume of the samples and in changes of the morphology of the joint surface. In three-point bending tests, the samples were examined in two opposite positions (Ti6Al4V on the top or Inconel 625 on the top). The results indicated to depend on the position in which the sample was tested.

Does Vertical Ground Reaction Force of the Hip, Knee, and Ankle Joints Change in Patients with Adolescent Idiopathic Scoliosis after Spinal Fusion?

PubMed

Yusof, Mohd Imran; Shaharudin, Shazlin; Sivalingarajah, Prema

2018-04-01

Comparative cross-sectional study. We measured the vertical ground reaction force (vGRF) of the hip, knee, and ankle joints during normal gait in normal patients, adolescent idiopathic scoliosis (AIS) patients with a Cobb angle <40° and in AIS patients with spinal fusion. We aimed to investigate whether vGRF in the aforementioned joints is altered in these three groups of patients. vGRF of the lower limb joints may be altered in these groups of patients. Although it is known that excessive force in the joints may induce early arthritis, there is limited relevant information in the literatures. We measured vGRF of the hip, knee, and ankle joints during heel strike, early stance, mid stance, and toe-off phases in normal subjects (group 1, n=14), AIS patients with Cobb angle <40° (group 2, n=14), and AIS patients with spinal fusion (group 3, n=13) using a gait analysis platform. Fifteen auto-reflective tracking markers were attached to standard anatomical landmarks in both the lower limbs. The captured motion images were used to define the orientations of the body segments and force exerted on the force plate using computer software. Statistical analysis was performed using independent t-test and analysis of variance to examine differences between the right and left sides as well as those among the different subject groups. The measurements during the four gait phases in all the groups did not show any significant difference ( p >0.05). In addition, no significant difference was found in the vGRF measurements of all the joints among the three groups ( p >0.05). A Cobb angle <40° and spinal fusion did not significantly create imbalance or alter vGRF of the lower limb joints in AIS patients.

The quantitative role of flexor sheath incision in correcting Dupuytren proximal interphalangeal joint contractures.

PubMed

Blazar, P E; Floyd, E W; Earp, B E

2016-07-01

Controversy exists regarding intra-operative treatment of residual proximal interphalangeal joint contractures after Dupuytren's fasciectomy. We test the hypothesis that a simple release of the digital flexor sheath can correct residual fixed flexion contracture after subtotal fasciectomy. We prospectively enrolled 19 patients (22 digits) with Dupuytren's contracture of the proximal interphalangeal joint. The average pre-operative extension deficit of the proximal interphalangeal joints was 58° (range 30-90). The flexion contracture of the joint was corrected to an average of 28° after fasciectomy. In most digits (20 of 21), subsequent incision of the flexor sheath further corrected the contracture by an average of 23°, resulting in correction to an average flexion contracture of 4.7° (range 0-40). Our results support that contracture of the tendon sheath is a contributor to Dupuytren's contracture of the joint and that sheath release is a simple, low morbidity addition to correct Dupuytren's contractures of the proximal interphalangeal joint. Additional release of the proximal interphalangeal joint after fasciectomy, after release of the flexor sheath, is not necessary in many patients. IV (Case Series, Therapeutic). © The Author(s) 2015.

Microstructural Influence on Mechanical Properties in Plasma Microwelding of Ti6Al4V Alloy

NASA Astrophysics Data System (ADS)

Baruah, M.; Bag, S.

2016-11-01

The complexity of joining Ti6Al4V alloy enhances with reduction in sheet thickness. The present work puts emphasis on microplasma arc welding (MPAW) of 500-μm-thick Ti6Al4V alloy in butt joint configuration. Using controlled and regulated arc current, the MPAW process is specifically designed to use in joining of thin sheet components over a wide range of process parameters. The weld quality is assessed by carefully controlling the process parameters and by reducing the formation of oxides. The combined effect of welding speed and current on the weld joint properties is evaluated for joining of Ti6Al4V alloy. The macro- and microstructural characterizations of the weldment by optical microscopy as well as the analysis of mechanical properties by microtensile and microhardness test have been performed. The weld joint quality is affected by specifically designed fixture that controls the oxidation of the joint and introduces high cooling rate. Hence, the solidified microstructure of welded specimen influences the mechanical properties of the joint. The butt joint of titanium alloy by MPAW at optimal process parameters is of very high quality, without any internal defects and with minimum residual distortion.

Joint-position sense is altered by football pre-participation warm-up exercise and match induced fatigue.

PubMed

Salgado, Eduardo; Ribeiro, Fernando; Oliveira, José

2015-06-01

The demands to which football players are exposed during the match may augment the risk of injury by decreasing the sense of joint position. This study aimed to assess the effect of pre-participation warm-up and fatigue induced by an official football match on the knee-joint-position sense of football players. Fourteen semi-professional male football players (mean age: 25.9±4.6 years old) volunteered in this study. The main outcome measures were rate of perceived exertion and knee-joint-position sense assessed at rest, immediately after a standard warm-up (duration 25 min), and immediately after a competitive football match (90 minutes duration). Perceived exertion increased significantly from rest to the other assessments (rest: 8.6±2.0; after warm-up: 12.1±2.1; after football match: 18.5±1.3; p<0.001). Compared to rest, absolute angular error decreased significantly after the warm-up (4.1°±2.2° vs. 2.0°±1.0°; p=0.0045). After the match, absolute angular error (8.7°±3.8°) increased significantly comparatively to both rest (p=0.001) and the end of warm-up (p<0.001). Relative error showed directional bias with an underestimation of the target position, which was higher after the football match compared to both rest (p<0.001) and after warm-up (p<0.001). The results indicate that knee-joint-position sense acuity was increased by pre-participation warm-up exercise and was decreased by football match-induced fatigue. Warm-up exercises could contribute to knee injury prevention, whereas the deleterious effect of match-induced fatigue on the sensorimotor system could ultimately contribute to knee instability and injury. Copyright © 2014 Elsevier B.V. All rights reserved.

Vacuum Brazing TC4 Titanium Alloy to 304 Stainless Steel with Cu-Ti-Ni-Zr-V Amorphous Alloy Foil

NASA Astrophysics Data System (ADS)

Dong, Honggang; Yang, Zhonglin; Wang, Zengrui; Deng, Dewei; Dong, Chuang

2014-10-01

Dissimilar metal vacuum brazing between TC4 titanium alloy and 304 stainless steel was conducted with newly designed Cu-Ti-Ni-Zr-V amorphous alloy foils as filler metals. Solid joints were obtained due to excellent compatibility between the filler metal and stainless steel substrate. Partial dissolution of stainless steel substrate occurred during brazing. The shear strength of the joint brazed with Cu43.75Ti37.5Ni6.25Zr6.25V6.25 foil was 105 MPa and that with Cu37.5Ti25Ni12.5Zr12.5V12.5 was 116 MPa. All the joints fractured through the gray layer in the brazed seam, revealing brittle fracture features. Cr4Ti, Cu0.8FeTi, Fe8TiZr3 and Al2NiTi3C compounds were found in the fractured joint brazed with Cu43.75Ti37.5Ni6.25Zr6.25V6.25 foil, and Fe2Ti, TiCu, Fe8TiZr3 and NiTi0.8Zr0.3 compounds were detected in the joint brazed with Cu37.5Ti25Ni12.5Zr12.5V12.5 foil. The existence of Cr-Ti, Fe-Ti, Cu-Fe-Ti, and Fe-Ti-V intermetallic compounds in the brazed seam caused fracture of the resultant joints.

Altered neuromuscular control and ankle joint kinematics during walking in subjects with functional instability of the ankle joint.

PubMed

Delahunt, Eamonn; Monaghan, Kenneth; Caulfield, Brian

2006-12-01

The ankle joint requires very precise neuromuscular control during the transition from terminal swing to the early stance phase of the gait cycle. Altered ankle joint arthrokinematics and muscular activity have been cited as potential factors that may lead to an inversion sprain during the aforementioned time periods. However, to date, no study has investigated patterns of muscle activity and 3D joint kinematics simultaneously in a group of subjects with functional instability compared with a noninjured control group during these phases of the gait cycle. To compare the patterns of lower limb 3D joint kinematics and electromyographic activity during treadmill walking in a group of subjects with functional instability with those observed in a control group. Controlled laboratory study. Three-dimensional angular velocities and displacements of the hip, knee, and ankle joints, as well as surface electromyography of the rectus femoris, peroneus longus, tibialis anterior, and soleus muscles, were recorded simultaneously while subjects walked on a treadmill at a velocity of 4 km/h. Before heel strike, subjects with functional instability exhibited a decrease in vertical foot-floor clearance (12.62 vs 22.84 mm; P < .05), as well as exhibiting a more inverted position of the ankle joint before, at, and immediately after heel strike (1.69 degrees , 2.10 degrees , and -0.09 degrees vs -1.43 degrees , -1.43 degrees , and -2.78 degrees , respectively [minus value = eversion]; P < .05) compared with controls. Subjects with functional instability were also observed to have an increase in peroneus longus integral electromyography during the post-heel strike time period (107.91%.millisecond vs 64.53%.millisecond; P < .01). The altered kinematics observed in this study could explain the reason subjects with functional instability experience repeated episodes of ankle inversion injury in situations with only slight or no external provocation. It is hypothesized that the observed

ARC-2012-ACD12-0020-005

NASA Image and Video Library

2012-02-10

Then and Now: These images illustrate the dramatic improvement in NASA computing power over the last 23 years, and its effect on the number of grid points used for flow simulations. At left, an image from the first full-body Navier-Stokes simulation (1988) of an F-16 fighter jet showing pressure on the aircraft body, and fore-body streamlines at Mach 0.90. This steady-state solution took 25 hours using a single Cray X-MP processor to solve the 500,000 grid-point problem. Investigator: Neal Chaderjian, NASA Ames Research Center At right, a 2011 snapshot from a Navier-Stokes simulation of a V-22 Osprey rotorcraft in hover. The blade vortices interact with the smaller turbulent structures. This very detailed simulation used 660 million grid points, and ran on 1536 processors on the Pleiades supercomputer for 180 hours. Investigator: Neal Chaderjian, NASA Ames Research Center; Image: Tim Sandstrom, NASA Ames Research Center

Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice.

PubMed

Williams, Aislinn J; Yee, Patricia; Smith, Mitchell C; Murphy, Geoffrey G; Umemori, Hisashi

2016-07-01

Specific growth factors induce formation and differentiation of excitatory and inhibitory synapses, and are essential for brain development and function. Fibroblast growth factor 22 (FGF22) is important for specifying excitatory synapses during development, including in the hippocampus. Mice with a genetic deletion of FGF22 (FGF22KO) during development subsequently have fewer hippocampal excitatory synapses in adulthood. As a result, FGF22KO mice are resistant to epileptic seizure induction. In addition to playing a key role in learning, the hippocampus is known to mediate mood and anxiety. Here, we explored whether loss of FGF22 alters affective, anxiety or social cognitive behaviors in mice. We found that relative to control mice, FGF22KO mice display longer duration of floating and decreased latency to float in the forced swim test, increased immobility in the tail suspension test, and decreased preference for sucrose in the sucrose preference test, which are all suggestive of a depressive-like phenotype. No differences were observed between control and FGF22KO mice in other behavioral assays, including motor, anxiety, or social cognitive tests. These results suggest a novel role for FGF22 specifically in affective behaviors. Copyright © 2016 Elsevier B.V. All rights reserved.

Electron density of Rhizophora spp. wood using Compton scattering technique at 15.77, 17.48 and 22.16 keV XRF energies

NASA Astrophysics Data System (ADS)

Shakhreet, B. Z.; Bauk, S.; Shukri, A.

2015-02-01

Compton (incoherently) scattered photons which are directly proportional to the electron density of the scatterer, have been employed in characterizing Rhizophora spp. as breast tissue equivalent. X-ray fluorescent scattered incoherently from Rhizophora spp. sample was measured using Si-PIN detector and three XRF energy values 15.77, 17.48 and 22.16 keV. This study is aimed at providing electron density information in support of the introduction of new tissue substitute materials for mammography phantoms.

Fatigue properties of dissimilar metal laser welded lap joints

NASA Astrophysics Data System (ADS)

Dinsley, Christopher Paul

This work involves laser welding austenitic and duplex stainless steel to zinc-coated mild steel, more specifically 1.2mm V1437, which is a Volvo Truck Coiporation rephosphorised mild steel. The work investigates both tensile and lap shear properties of similar and dissimilar metal laser welded butt and lap joints, with the majority of the investigation concentrating on the fatigue properties of dissimilar metal laser welded lap joints. The problems encountered when laser welding zinc-coated steel are addressed and overcome with regard to dissimilar metal lap joints with stainless steel. The result being the production of a set of guidelines for laser welding stainless steel to zinc-coated mild steel. The stages of laser welded lap joint fatigue life are defined and the factors affecting dissimilar metal laser welded lap joint fatigue properties are analysed and determined; the findings suggesting that dissimilar metal lap joint fatigue properties are primarily controlled by the local stress at the internal lap face and the early crack growth rate of the material at the internal lap face. The lap joint rotation, in turn, is controlled by sheet thickness, weld width and interfacial gap. Laser welded lap joint fatigue properties are found to be independent of base material properties, allowing dissimilar metal lap joints to be produced without fatigue failure occurring preferentially in the weaker parent material, irrespective of large base material property differences. The effects of Marangoni flow on the compositions of the laser weld beads are experimentally characterised. The results providing definite proof of the stirring mechanism within the weld pool through the use of speeds maps for chromium and nickel. Keywords: Laser welding, dissimilar metal, Zinc-coated mild steel, Austenitic stainless steel, Duplex stainless steel, Fatigue, Lap joint rotation, Automotive.

Atlas V Launch Incorporated NASA Glenn Thermal Barrier

NASA Technical Reports Server (NTRS)

Dunlap, Patrick H., Jr.; Steinetz, Bruce M.

2004-01-01

In the Spring of 2002, Aerojet experienced a major failure during a qualification test of the solid rocket motor that they were developing for the Atlas V Enhanced Expendable Launch Vehicle. In that test, hot combustion gas reached the O-rings in the nozzle-to-case joint and caused a structural failure that resulted in loss of the nozzle and aft dome sections of the motor. To improve the design of this joint, Aerojet decided to incorporate three braided carbon-fiber thermal barriers developed at the NASA Glenn Research Center. The thermal barriers were used to block the searing-hot 5500 F pressurized gases from reaching the temperature-sensitive O-rings that seal the joint. Glenn originally developed the thermal barriers for the nozzle joints of the space shuttle solid rocket motors, and Aerojet decided to use them on the basis of the results of several successful ground tests of the thermal barriers in the shuttle rockets. Aerojet undertook an aggressive schedule to redesign the rocket nozzle-to-case joint with the thermal barriers and to qualify it in time for a launch planned for the middle of 2003. They performed two successful qualification tests (Oct. and Dec. 2002) in which the Glenn thermal barriers effectively protected the O-rings. These qualification tests saved hundreds of thousands of dollars in development costs and put the Lockheed-Martin/Aerojet team back on schedule. On July 17, 2003, the first flight of an Atlas V boosted with solid rocket motors successfully launched a commercial satellite into orbit from Cape Canaveral Air Force Station. Aero-jet's two 67-ft solid rocket boosters performed flawlessly, with each providing thrust in excess of 250,000 lbf. Both motors incorporated three Glenn-developed thermal barriers in their nozzle-to-case joints. The Cablevision satellite launched on this mission will be used to provide direct-to-home satellite television programming for the U.S. market starting in late 2003. The Atlas V is a product of the

Thickness Distribution of Glenohumeral Joint Cartilage

PubMed Central

Schleich, Christoph; Bittersohl, Bernd; Antoch, Gerald; Krauspe, Rüdiger; Zilkens, Christoph; Kircher, Jörn

2016-01-01

High-resolution 3-dimensional cartilage-specific magnetic resonance imaging (MRI) was performed at 3 T to test the following hypotheses: (1) there is a nonuniform cartilage thickness distribution both on the proximal humerus and on the glenoid surface and (2) the glenohumeral joint as a combined system is congruent with the level of the joint cartilage surface without substantial radial mismatch. Inclusion of 38 volunteers (19 females, mean age 24.34 ± 2.22 years; range 21-29 years) in a prospective study. Measurements of: cartilage thickness in 3 regions and 3 zones; radius of both circles (glenoid and humeral cartilage) for congruency calculation using 3-T MRI with 3-dimensional dual-echo steady-state sequence with water excitation. A homogenous mean cartilage thickness (1.2-1.5 mm) and slightly higher values for the glenoidal articulating surface radii both in the mid-paracoronar section (2.4 vs. 2.1 cm, P < 0.001) and in the mid-paraaxial section (2.4 vs. 2.1 cm, P < 0.001) compared with the humeral side were observed. The concept of a radial mismatch between the humeral head and the glenoid in healthy human subjects can be confirmed. This study provides normative data for the comparison of joint cartilage changes at the shoulder for future studies. PMID:28345405

Cyclic movement stimulates hyaluronan secretion into the synovial cavity of rabbit joints

PubMed Central

Ingram, K R; Wann, A K T; Angel, C K; Coleman, P J; Levick, J R

2008-01-01

The novel hypothesis that the secretion of the joint lubricant hyaluronan (HA) is coupled to movement has implications for normal function and osteoarthritis, and was tested in the knee joints of anaesthetized rabbits. After washing out the endogenous synovial fluid HA (miscibility coefficient 0.4), secretion into the joint cavity was measured over 5 h in static joints and in passively cycled joints. The net static secretion rate (11.2 ± 0.7 μg h−1, mean ± s.e.m., n = 90) correlated with the variable endogenous HA mass (mean 367 ± 8 μg), with a normalized value of 3.4 ± 0.2 μg h−1 (100 μg)−1 . Cyclic joint movement approximately doubled the net HA secretion rate to 22.6 ± 1.2 μg h−1 (n = 77) and raised the normalized percentage to 5.9 ± 0.3 μg h−1 (100 μg)−1. Secretion was inhibited by 2-deoxyglucose and iodoacetate, confirming active secretion. The net accumulation rate underestimated true secretion rate due to some trans-synovial loss. HA turnover time (endogenous mass/secretion rate) was 17–30 h (static) to 8–15 h (moved) The results demonstrate for the first time that the active secretion of HA is coupled to joint usage. Movement–secretion coupling may protect joints against the damaging effects of repetitive joint use, replace HA lost during periods of immobility (overnight), and contribute to the clinical benefit of exercise therapy in moderate osteoarthritis. PMID:18202097

4 CFR 22.4 - Appeal File [Rule 4].

Code of Federal Regulations, 2010 CFR

2010-01-01

... contracting officer relied in making the decision, and any correspondence relating thereto; (v) Transcripts of... 4 Accounts 1 2010-01-01 2010-01-01 false Appeal File [Rule 4]. 22.4 Section 22.4 Accounts... consisting of all documents pertinent to the appeal, including: (i) The decision from which the appeal is...

KSC-03pd0948

NASA Image and Video Library

2003-04-02

KENNEDY SPACE CENTER, FLA. -- A pair of nesting ospreys now occupy a nest recently constructed on a speaker in the lower parking lot of the Press Site. Eggs have been sighted in the nest. The NASA logo seen in the background is on the nearby Vehicle Assembly Building. Known as a fish hawk, the osprey selects sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States it is found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

KSC-03pd0951

NASA Image and Video Library

2003-04-02

KENNEDY SPACE CENTER, FLA. -- A pair of nesting ospreys now occupy a nest recently constructed on a speaker in the lower parking lot of the Press Site. Eggs have been sighted in the nest. The NASA logo seen in the background is on the nearby Vehicle Assembly Building. Known as a fish hawk, the osprey selects sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States it is found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

KSC-03pd0947

NASA Image and Video Library

2003-04-02

KENNEDY SPACE CENTER, FLA. - A female osprey occupies a nest recently constructed on a speaker in the lower parking lot of the Press Site. Eggs have been sighted in the nest. The NASA logo seen in the background is on the nearby Vehicle Assembly Building. Known as a fish hawk, the osprey selects sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States it is found from Alaska to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

KSC-2011-4046

NASA Image and Video Library

2011-05-25

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, an adult osprey keeps an eye on its young from a pole near the Press Site parking lot. The VAB and Press Site are located at the Turn Basin in Launch Complex 39, making it an ideal osprey nesting place. The Merritt Island National Wildlife Refuge overlaps with Kennedy Space Center property and provides a habitat for many types of wildlife, including the osprey, and 330 species of birds. For information on the refuge, visit http://www.fws.gov/merrittisland/Index.html. Photo credit: NASA/Jack Pfaller

Triangular Titanium Implants for Minimally Invasive Sacroiliac Joint Fusion: A Prospective Study.

PubMed

Duhon, Bradley S; Cher, Daniel J; Wine, Kathryn D; Kovalsky, Don A; Lockstadt, Harry

2016-05-01

Study Design Prospective multicenter single-arm interventional clinical trial. Objective To determine the degree of improvement in sacroiliac (SI) joint pain, disability related to SI joint pain, and quality of life in patients with SI joint dysfunction who undergo minimally invasive SI joint fusion using triangular-shaped titanium implants. Methods Subjects (n = 172) underwent minimally invasive SI joint fusion between August 2012 and January 2014 and completed structured assessments preoperatively and at 1, 3, 6, and 12 months postoperatively, including a 100-mm SI joint and back pain visual analog scale (VAS), Oswestry Disability Index (ODI), Short Form-36 (SF-36), and EuroQOL-5D. Patient satisfaction with surgery was assessed at 6 and 12 months. Results Mean SI joint pain improved from 79.8 at baseline to 30.0 and 30.4 at 6 and 12 months, respectively (mean improvements of 49.9 and 49.1 points, p < 0.0001 each). Mean ODI improved from 55.2 at baseline to 32.5 and 31.4 at 6 and 12 months (improvements of 22.7 and 23.9 points, p < 0.0001 each). SF-36 physical component summary improved from 31.7 at baseline to 40.2 and 40.3 at 6 and 12 months (p < 0.0001). At 6 and 12 months, 93 and 87% of subjects, respectively, were somewhat or very satisfied and 92 and 91%, respectively, would have the procedure again. Conclusions Minimally invasive SI joint fusion resulted in improvement of pain, disability, and quality of life in patients with SI joint dysfunction due to degenerative sacroiliitis and SI joint disruption.

Triangular Titanium Implants for Minimally Invasive Sacroiliac Joint Fusion: A Prospective Study

PubMed Central

Duhon, Bradley S.; Cher, Daniel J.; Wine, Kathryn D.; Kovalsky, Don A.; Lockstadt, Harry

2015-01-01

Study Design Prospective multicenter single-arm interventional clinical trial. Objective To determine the degree of improvement in sacroiliac (SI) joint pain, disability related to SI joint pain, and quality of life in patients with SI joint dysfunction who undergo minimally invasive SI joint fusion using triangular-shaped titanium implants. Methods Subjects (n = 172) underwent minimally invasive SI joint fusion between August 2012 and January 2014 and completed structured assessments preoperatively and at 1, 3, 6, and 12 months postoperatively, including a 100-mm SI joint and back pain visual analog scale (VAS), Oswestry Disability Index (ODI), Short Form-36 (SF-36), and EuroQOL-5D. Patient satisfaction with surgery was assessed at 6 and 12 months. Results Mean SI joint pain improved from 79.8 at baseline to 30.0 and 30.4 at 6 and 12 months, respectively (mean improvements of 49.9 and 49.1 points, p < 0.0001 each). Mean ODI improved from 55.2 at baseline to 32.5 and 31.4 at 6 and 12 months (improvements of 22.7 and 23.9 points, p < 0.0001 each). SF-36 physical component summary improved from 31.7 at baseline to 40.2 and 40.3 at 6 and 12 months (p < 0.0001). At 6 and 12 months, 93 and 87% of subjects, respectively, were somewhat or very satisfied and 92 and 91%, respectively, would have the procedure again. Conclusions Minimally invasive SI joint fusion resulted in improvement of pain, disability, and quality of life in patients with SI joint dysfunction due to degenerative sacroiliitis and SI joint disruption. PMID:27099817

The Joint Logistics Enterprise Enables Operation United Assistance

DTIC Science & Technology

2016-02-24

Sustainment July–August 2015 JLE U.S. service members board a C-130 Hercules aircraft Oct. 22, 2014, in Dakar, Senegal, to travel to Liberia to...including Liberia , as the “least developed in the world.” With numerous governance challenges, harsh weather, limited infrastructure over a... Liberia with the USARAF G–4, who was also the Joint Forces Com- mand ( JFC) J–4, and 7 personnel from his directorate. Because of the global reach of

Determination of Parachute Joint Factors using Seam and Joint Testing

NASA Technical Reports Server (NTRS)

Mollmann, Catherine

2015-01-01

This paper details the methodology for determining the joint factor for all parachute components. This method has been successfully implemented on the Capsule Parachute Assembly System (CPAS) for the NASA Orion crew module for use in determining the margin of safety for each component under peak loads. Also discussed are concepts behind the joint factor and what drives the loss of material strength at joints. The joint factor is defined as a "loss in joint strength...relative to the basic material strength" that occurs when "textiles are connected to each other or to metals." During the CPAS engineering development phase, a conservative joint factor of 0.80 was assumed for each parachute component. In order to refine this factor and eliminate excess conservatism, a seam and joint testing program was implemented as part of the structural validation. This method split each of the parachute structural joints into discrete tensile tests designed to duplicate the loading of each joint. Breaking strength data collected from destructive pull testing was then used to calculate the joint factor in the form of an efficiency. Joint efficiency is the percentage of the base material strength that remains after degradation due to sewing or interaction with other components; it is used interchangeably with joint factor in this paper. Parachute materials vary in type-mainly cord, tape, webbing, and cloth -which require different test fixtures and joint sample construction methods. This paper defines guidelines for designing and testing samples based on materials and test goals. Using the test methodology and analysis approach detailed in this paper, the minimum joint factor for each parachute component can be formulated. The joint factors can then be used to calculate the design factor and margin of safety for that component, a critical part of the design verification process.

[Diagnostic test scale SI5: Assessment of sacroiliac joint dysfunction].

PubMed

Acevedo González, Juan C; Quintero Oliveros, Silvia

2015-01-01

Sacroiliac joint dysfunction is a known cause of low back pain. We think that a diagnostic score scale (SI5) may be performed to assess diagnostic utility of clinical signs of sacroiliac joint dysfunction. The primary aim of the present study was to conduct the pilot study of our new diagnostic score scale, the SI5, for sacroiliac joint syndrome. We reviewed the literature on clinical characteristics, diagnostic tests and imaging most commonly used in diagnosing sacroiliac joint dysfunction. Our group evaluated the diagnostic utility of these aspects and we used those considered most representative to develop the SI5 diagnostic scale. The SI5 scale was applied to 22 patients with low back pain; afterwards, the standard test for diagnosing this pathology (selective blockage of the SI joint) was also performed on these patients. The sensitivity and specificity for each sign were also assessed and the diagnostic scale called SI5 was then proposed, based on these data. The most sensitive clinical tests for diagnosing SI joint dysfunction were 2 patient-reported clinical characteristics, the Laguerre Test, sacroiliac rocking test and Yeomans test (greater than 80% sensitivity). The tests with greatest diagnostic specificity (>80%) were the Lewitt test, Piedallu test and Gillet test. The proposed SI5 test score scale showed sensitivity of 73% and specificity of 71%. Sacroiliac joint syndrome has been shown to produce low back pain frequently; however, the diagnostic value of examination tests for sacroiliac joint pain has been questioned by other authors. The pilot study on the SI5 diagnostic score scale showed good sensitivity and specificity. However, the process of statistical validation of the SI5 needs to be continued. Copyright © 2014 Sociedad Española de Neurocirugía. Published by Elsevier España. All rights reserved.

Imageological measurement of the sternoclavicular joint and its clinical application.

PubMed

Li, Ming; Wang, Bo; Zhang, Qi; Chen, Wei; Li, Zhi-Yong; Qin, Shi-Ji; Zhang, Ying-Ze

2012-01-01

Dislocation of the sternoclavicular joint is rare. However, posterior dislocation compressing important structures in the mediastinum may be fatal. Early diagnosis and prompt therapy of sternoclavicular joint dislocation are important. Computed tomography (CT) is an optimal means to investigate sternoclavicular joint anatomy; however, there are few reports on the imageological anatomical features of the sternoclavicular joint. The study investigated imageological anatomical features, and a new plate was devised according to these data to treat sternoclavicular joint dislocation. Fifty-three healthy Chinese volunteers examined with chest CT were included in the study. The coronal, sagittal, and axial images of the sternoclavicular region were reconstructed. The sternal head diameter in the inferolateral-to-superomedial direction, length of the clavicular notch, and angle between the clavicular notch and sternum were measured on coronal images. The angle between the presternum and trunk was measured on sagittal images. The following dimensions were measured on axial images: anteroposterior dimensions of the sternal head, clavicular notch, and presternum; width of the sternoclavicular joint; distance between bilateral clavicles; and minimal distance from the presternum to the underlying structures in the thoracic cavity. A new plate was designed according to the above data and was used to repair six sternoclavicular joint dislocations. All cases were followed up with a range of 9 to 12 months. The proximal clavicle is higher than the presternum in a horizontal position. On axial images, the anteroposterior dimension of the sternal head was longer than the presternum, and the center region of the presternum was thinner than the edges. The left sternoclavicular joint space was (0.82 ± 0.21) cm, and the right was (0.87 ± 0.22) cm. Among the structures behind the sternum, the left bilateral innominate vein ran nearest to the presternum. The distance from the anterior

Life Assessment for Cr-Mo Steel Dissimilar Joints by Various Filler Metals Using Accelerated Creep Testing

NASA Astrophysics Data System (ADS)

Petchsang, S.; Phung-on, I.; Poopat, B.

2016-12-01

Accelerated creep rupture tests were performed on T22/T91 dissimilar metal joints to determine the fracture location and rupture time of different weldments. Four configurations of deposited filler metal were tested using gas tungsten arc welding to estimate the service life for Cr-Mo steel dissimilar joints at elevated temperatures in power plants. Results indicated that failure in all configurations occurred in the tempered original microstructure and tempered austenite transformation products (martensite or bainite structure) as type IV cracking at the intercritical area of the heat-affected zone (ICHAZ) for both T22 and T91 sides rather than as a consequence of the different filler metals. Creep damage occurred with the formation of precipitations and microvoids. The correlation between applied stress and the Larson-Miller parameter (PLM) was determined to predict the service life of each material configuration. Calculated time-to-failure based on the PLM and test results for both temperature and applied stress parameters gave a reasonable fit. The dissimilar joints exhibited lower creep rupture compared to the base material indicating creep degradation of the weldment.

Spacesuit mobility joints

NASA Technical Reports Server (NTRS)

Vykukal, H. C. (Inventor)

1978-01-01

Joints for use in interconnecting adjacent segments of an hermetically sealed spacesuit which have low torques, low leakage and a high degree of reliability are described. Each of the joints is a special purpose joint characterized by substantially constant volume and low torque characteristics. Linkages which restrain the joint from longitudinal distension and a flexible, substantially impermeable diaphragm of tubular configuration spanning the distance between pivotally supported annuli are featured. The diaphragms of selected joints include rolling convolutions for balancing the joints, while various joints include wedge-shaped sections which enhance the range of motion for the joints.

[Treatment of complete acromioclavicular joint dislocation with transfer of the medial half of the coracoacromial ligament to reconstruct the coracoclavicular ligament].

PubMed

Dong, Wen-Wei; Shi, Zeng-Yuan; Liu, Zheng-Xin; Mao, Hai-Jiao

2015-04-01

To explore the operation methods and clinical effects of transfer of the medial half of the coracoacromial ligament to reconstruct the coracoclavicular ligament in treating complete acromioclavicular joint dislocation. From January 2006 to June 2012,26 patients with acute complete acromioclavicular joint dislocation underwent surgery. Transfer of the medial half of the coracoacromial ligament to reconstruct the coracoclavicular ligament, additional clavical hoot plate and Kirschner wires fixation, were performed in all the patients. Among the patients, 18 patients were male and 8 patients were female, with an average age of 36.7 years old (ranged from 25 to 51 years). The duration from injury to operation was from 3 to 12 days with an average of 5 days. According to the Rockwood classification, 4 cases were grade III and 22 cases were grade V . Clinical manifestation included local swelling, tenderness with snapping, limitation of shoulder joint motion. In preoperative bilateral shoulder joint X-rays, the injured coracoclavicular distance was (16.2 ± 5.0) mm which was significantly wider than that of uninjured sides (7.6 ± 1.0) mm. Clinical results were evaluated according to X-rays and Constant-Murley score. All incisions obtained primary healing after operation without complication of infection, internal fixation breakage, redislocation. All the patients were followed up from 12 to 30 months with an average of 18 months. Kirschner wires and internal fixation plate were removed at 1 month and 8-10 months after operation, respectively. At final follow-up, the motion of shoulder joint recovered to normal and a no pain joint was obtained. According to Constant-Murley score, 24 cases got excellent results and 2 cases good. There was no significant difference after operation between the injured coracoclavicular distance and the uninjured contralateral side [(7.7 ± 1.2) mm vs (7.6 ± 1.0) mm), P > 0.05]. Transfer of the medial half of the coracoacromial ligament to

Joint University Program for Air Transportation Research, 1991-1992

NASA Technical Reports Server (NTRS)

Morrell, Frederick R. (Compiler)

1993-01-01

This report summarizes the research conducted during the academic year 1991-1992 under the FAA/NASA sponsored Joint University Program for Air Transportation Research. The year end review was held at Ohio University, Athens, Ohio, June 18-19, 1992. The Joint University Program is a coordinated set of three grants sponsored by the Federal Aviation Administration and NASA Langley Research Center, one each with the Massachusetts Institute of Technology (NGL-22-009-640), Ohio University (NGR-36-009-017), and Princeton University (NGL-31-001-252). Completed works, status reports, and annotated bibliographies are presented for research topics, which include navigation, guidance and control theory and practice, intelligent flight control, flight dynamics, human factors, and air traffic control processes. An overview of the year's activities for each university is also presented.

The Syntheses and Structure of the First Vanadium(IV) and Vanadium(V) Binary Azides, V(N3)4, [V(N3)6]2- and [V(N3)6]- (Preprint)

DTIC Science & Technology

2009-11-17

V(N3)3(N3S2)] 2- , [22] have been reported, and no binary vanadium(V) compounds had been known except for VF5, VF6 - and V2O5 . By analogy with...valves. Volatile materials were handled in a Pyrex glass or stainless steel/Teflon-FEP vacuum line. [31] All reaction vessels were passivated with ClF3...successful synthesis of the [V(N3)6] - anion, the only binary vanadium(V) compound known besides VF5, VF6 - and V2O5 . N1’ N8 N9 N1 N2 N3 V N4 N5 N6 N2

Fatigue performance of joints executed in pure titanium structures with several diameters.

PubMed

Nuñez-Pantoja, Juliana Maria Costa; Vaz, Luis Geraldo; Nóbilo, Mauro Antônio de Arruda; Mesquita, Marcelo Ferraz

2011-01-01

This study evaluated fatigue strength of CP-Ti laser-welded joints. Sixty (20/diameter) CP-Ti casted dumbbell rods with diameters of 1.5, 2.0, and 3.5 mm were sectioned and welded using two joint openings (0.0 (00) and 0.6 mm (06)). Six groups were formed, amounting to a total of 9 (n=10) with inclusion of intact groups. Welding was executed using 360 V/8 ms (1.5 and 2.0 mm) and 380 V/9 ms (3.5 mm). Joints were finished, polished, and submitted to radiographic examination to visually analyze presence of porosity (PP). Specimens were submitted to cyclic tests, and the number of cycles until failure (NC) was recorded. Fractured surfaces were examined by SEM. Kruskal-Wallis and Dunn (α=0.05) tests demonstrated that NC was lower for all diameters with 06, and for 3.5 mm/00. NC and PP were found to have a negative correlation (Spearman Coefficient). For CP-Ti frameworks with thin diameters, laser welding is better when structures are juxtaposed.

Physicochemical and microscopic characterization of implant–abutment joints

PubMed Central

Lopes, Patricia A.; Carreiro, Adriana F. P.; Nascimento, Rubens M.; Vahey, Brendan R.; Henriques, Bruno; Souza, Júlio C. M.

2018-01-01

Objective: The purpose of this study was to investigate Morse taper implant–abutment joints by chemical, mechanical, and microscopic analysis. Materials and Methods: Surfaces of 10 Morse taper implants and the correlated abutments were inspected by field emission gun-scanning electron microscopy (FEG-SEM) before connection. The implant–abutment connections were tightened at 32 Ncm. For microgap evaluation by FEG-SEM, the systems were embedded in epoxy resin and cross-sectioned at a perpendicular plane of the implant–abutment joint. Furthermore, nanoindentation tests and chemical analysis were performed at the implant–abutment joints. Statistics: Results were statistically analyzed via one-way analysis of variance, with a significance level of P < 0.05. Results: Defects were noticed on different areas of the abutment surfaces. The minimum and maximum size of microgaps ranged from 0.5 μm up to 5.6 μm. Furthermore, defects were detected throughout the implant–abutment joint that can, ultimately, affect the microgap size after connection. Nanoindentation tests revealed a higher hardness (4.2 ± 0.4 GPa) for abutment composed of Ti6Al4V alloy when compared to implant composed of commercially pure Grade 4 titanium (3.2 ± 0.4 GPa). Conclusions: Surface defects produced during the machining of both implants and abutments can increase the size of microgaps and promote a misfit of implant–abutment joints. In addition, the mismatch in mechanical properties between abutment and implant can promote the wear of surfaces, affecting the size of microgaps and consequently the performance of the joints during mastication. PMID:29657532

Physicochemical and microscopic characterization of implant-abutment joints.

PubMed

Lopes, Patricia A; Carreiro, Adriana F P; Nascimento, Rubens M; Vahey, Brendan R; Henriques, Bruno; Souza, Júlio C M

2018-01-01

The purpose of this study was to investigate Morse taper implant-abutment joints by chemical, mechanical, and microscopic analysis. Surfaces of 10 Morse taper implants and the correlated abutments were inspected by field emission gun-scanning electron microscopy (FEG-SEM) before connection. The implant-abutment connections were tightened at 32 Ncm. For microgap evaluation by FEG-SEM, the systems were embedded in epoxy resin and cross-sectioned at a perpendicular plane of the implant-abutment joint. Furthermore, nanoindentation tests and chemical analysis were performed at the implant-abutment joints. Results were statistically analyzed via one-way analysis of variance, with a significance level of P < 0.05. Defects were noticed on different areas of the abutment surfaces. The minimum and maximum size of microgaps ranged from 0.5 μm up to 5.6 μm. Furthermore, defects were detected throughout the implant-abutment joint that can, ultimately, affect the microgap size after connection. Nanoindentation tests revealed a higher hardness (4.2 ± 0.4 GPa) for abutment composed of Ti6Al4V alloy when compared to implant composed of commercially pure Grade 4 titanium (3.2 ± 0.4 GPa). Surface defects produced during the machining of both implants and abutments can increase the size of microgaps and promote a misfit of implant-abutment joints. In addition, the mismatch in mechanical properties between abutment and implant can promote the wear of surfaces, affecting the size of microgaps and consequently the performance of the joints during mastication.

NuSTAR and Swift joint view of neutron star X-ray binary 4U 1728-34: disc reflection in the island and lower banana states

NASA Astrophysics Data System (ADS)

Mondal, Aditya S.; Pahari, Mayukh; Dewangan, G. C.; Misra, R.; Raychaudhuri, B.

2017-04-01

We analyse two simultaneous NuSTAR and Swift data of the Atoll-type neutron star (NS) X-ray binary 4U 1728-34 observed on 2013 October 1 and 3. We infer that the first and the second observations belong to the island state and the lower banana state, respectively. During island state, four type-I X-ray bursts are observed within 60 ks exposure. From the time-resolved spectral analysis of each burst with NuSTAR, the blackbody temperature kTbb are found to vary between 1.3 and 3.0 keV, while the blackbody normalizations (km/10 kpc)2 vary in the range 20-200, which translates to blackbody radii of 3.5-7.4 km for an assumed distance of 5 kpc. The persistent, joint energy spectra from Swift and NuSTAR for both observations in the energy band 1-79 keV are well described with thermal emission from the NS surface (kTbb ≃ 1-2.5 keV), Comptonized emission of thermal seed photons from the hot boundary layer/corona and the strong reflection component from the accretion disc. We detect a broad iron line in the 5-8 keV band and reflection hump in the 15-30 keV band modelled by the relxill reflection model. Joint spectral fitting constrains the inclination angle of the binary system and inner disc radius to be 22°-40° and (2.0-4.3) × RISCO, respectively. We estimate the magnetic field to be (1.8-6.5) × 108 G. The X-ray luminosity of the source during the island and lower banana states are found to be LX = 1.1 and 1.6 × 1037 erg s-1, respectively, which correspond to ˜6 per cent and ˜9 per cent of the Eddington luminosity.

A JOINT CHANDRA AND SWIFT VIEW OF THE 2015 X-RAY DUST-SCATTERING ECHO OF V404 CYGNI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heinz, S.; Corrales, L.; Neilsen, J.

2016-07-01

We present a combined analysis of the Chandra and Swift observations of the 2015 X-ray echo of V404 Cygni. Using a stacking analysis, we identify eight separate rings in the echo. We reconstruct the soft X-ray light curve of the 2015 June outburst using the high-resolution Chandra images and cross-correlations of the radial intensity profiles, indicating that about 70% of the outburst fluence occurred during the bright flare at the end of the outburst on MJD 57199.8. By deconvolving the intensity profiles with the reconstructed outburst light curve, we show that the rings correspond to eight separate dust concentrations withmore » precise distance determinations. We further show that the column density of the clouds varies significantly across the field of view, with the centroid of most of the clouds shifted toward the Galactic plane, relative to the position of V404 Cyg, invalidating the assumption of uniform cloud column typically made in attempts to constrain dust properties from light echoes. We present a new XSPEC spectral dust-scattering model that calculates the differential dust-scattering cross section for a range of commonly used dust distributions and compositions and use it to jointly fit the entire set of Swift echo data. We find that a standard Mathis–Rumpl–Nordsieck model provides an adequate fit to the ensemble of echo data. The fit is improved by allowing steeper dust distributions, and models with simple silicate and graphite grains are preferred over models with more complex composition.« less

Cost analysis of debridement and retention for management of prosthetic joint infection.

PubMed

Peel, T N; Dowsey, M M; Buising, K L; Liew, D; Choong, P F M

2013-02-01

Prosthetic joint infection remains one of the most devastating complications of arthroplasty. Debridement and retention of the prosthesis is an attractive management option in carefully selected patients. Despite this, there are no data investigating the cost of this management modality for prosthetic joint infections. The aim of this case-control study was to calculate the cost associated with debridement and retention for management of prosthetic joint infection compared with primary joint replacement surgery without prosthetic joint infection. From 1 January 2008 to 30 June 2010, there were 21 prosthetic joint infections matched to 42 control patients. Controls were matched to cases according to the arthroplasty site, age and sex. Cases had a greater number of unplanned readmissions (100% vs. 7.1%; p <0.001), more additional surgery (3.3 vs. 0.07; p <0.001) and longer total bed days (31.6 vs. 7.9 days; p <0.001). In addition they had more inpatient, outpatient and emergency department visits (p <0.001, respectively). For patients with prosthetic joint infection the total cost, including index operation and costs of management of the prosthetic joint infection, was 3.1 times the cost of primary arthoplasty; the mean cost for cases was Australian dollars (AUD) $69,414 (±29,869) compared with $22,085 (±8147) (p <0.001). The demand for arthroplasty continues to grow and with that, the number of prosthetic joint infections will also increase, placing significant burden on the health system. Our study adds significantly to the growing body of evidence highlighting the substantial costs associated with prosthetic joint infection. © 2011 The Authors. Clinical Microbiology and Infection © 2011 European Society of Clinical Microbiology and Infectious Diseases.

Budget Options for National Defense

DTIC Science & Technology

2000-03-01

Corps’s V -22 Aircraft 51 3-19-A Reduce Purchases of the Air Force’s F-22 Fighter 52 3-19-B Cancel Production of the...of 13 very quiet subma- rines by 2012, meeting the Joint Chiefs’ requirement. Option 3-18 Defer Purchases of the Marine Corps’s V -22 Aircraft...110 -658 -113 3,270 -2,285 RELATED CBO PUBLICATION: Moving the Marine Corps by Sea in the 1990s (Study), October 1989. The V -22 aircraft, which

Large-Scale V/STOL Experimental Investigations of an Ejector-Lift Fighter and a Twin Tilt-Nacelle Transport

NASA Technical Reports Server (NTRS)

Dudley, Michael R.

2016-01-01

In the 1980s NASA Aeronautics was actively involved in full-scale wind tunnel testing of promising VSTOL aircraft concepts. This presentation looks at two, a multi-role fighter and a subsonic tactical transport. Their strengths and weaknesses are discussed with some of the rationale that ultimately led to the selection of competing concepts for production, namely the V-22 Osprey and the F-35 Lightning. The E7-A STOVL multi-role fighter was the product of an aircraft development program in the late 1980s by NASA, the Defense Advanced Research Projects Agency (DARPA), the Canadian Department of Industry Science and Technology (DIST), and industry partners General Dynamics and Boeing Dehavilland. The program was conducted an in response to increasing US-UK interest in supersonic STOVL fighters. The objective was to design an aircraft that could replace most existing close air support-air combat fighters with a single aircraft that had some of the qualities of an air superiority fighter and the deployment flexibility of a VSTOL aircraft. The resulting E7-A concept was a delta-wing supersonic fighter that used a fuselage-mounted thrust augmenting ejector and a ventral deflecting jet nozzle for vertical lift. The Grumman Aircraft Company, the Navy, and NASA developed the Design-698 (D-698) subsonic tactical transport in response to the Navy's Type A VSTOL utility aircraft requirement. The objective was to develop a subsonic utility transport with the operational flexibility of a helicopter, but with greater speed and range. The D-698 employs two high-bypass turbofan engines mounted on a dumbbell that rotates through ninety degrees for vertical takeoff and cruise flight. Movable vanes positioned in the exhaust flow provide control in hover with the need for reaction control jets. The presentations concluding comments suggest that technology advances in the last thirty-years may justify the value of revisiting some of these concepts.

Periprosthetic joint infection: are patients with multiple prosthetic joints at risk?

PubMed

Jafari, S Mehdi; Casper, David S; Restrepo, Camilo; Zmistowski, Benjamin; Parvizi, Javad; Sharkey, Peter F

2012-06-01

Patients who present with a periprosthetic joint infection in a single joint may have multiple prosthetic joints. The risk of these patients developing a subsequent infection in another prosthetic joint is unknown. Our purposes were (1) to identify the risk of developing a subsequent infection in another prosthetic joint and (2) to describe the time span and organism profile to the second prosthetic infection. We retrospectively identified 55 patients with periprosthetic joint infection who had another prosthetic joint in place at the time of presentation. Of the 55 patients, 11 (20%) developed a periprosthetic joint infection in a second joint. The type of organism was the same as the first infection in 4 (36%) of 11 patients. The time to developing a second infection averaged 2.0 years (range, 0-6.9 years). Copyright © 2012 Elsevier Inc. All rights reserved.

Classical and numerical approaches to determining V-section band clamp axial stiffness

NASA Astrophysics Data System (ADS)

Barrans, Simon M.; Khodabakhshi, Goodarz; Muller, Matthias

2015-01-01

V-band clamp joints are used in a wide range of applications to connect circular flanges, for ducts, pipes and the turbocharger housing. Previous studies and research on V-bands are either purely empirical or analytical with limited applicability on the variety of V-band design and working conditions. In this paper models of the V-band are developed based on the classical theory of solid mechanics and the finite element method to study the behaviour of theV-bands under axial loading conditions. The good agreement between results from the developed FEA and the classical model support the suitability of the latter to modelV-band joints with diameters greater than 110mm under axial loading. The results from both models suggest that the axial stiffness for thisV-band cross section reaches a peak value for V-bands with radius of approximately 150 mmacross a wide range of coefficients of friction. Also, it is shown that the coefficient of friction and the wedge angle have a significant effect on the axial stiffness of V-bands.

KSC-03pd0950

NASA Image and Video Library

2003-04-02

KENNEDY SPACE CENTER, FLA. -- While the female osprey eats fish brought by her mate, the male guards the nest, recently constructed on a speaker in the lower parking lot of the Press Site. Eggs have been sighted in the nest. The NASA logo seen in the background is on the nearby Vehicle Assembly Building. Known as a fish hawk, the osprey selects sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

Joint crisis plans and psychiatric advance directives in German psychiatric practice.

PubMed

Radenbach, Katrin; Falkai, Peter; Weber-Reich, Traudel; Simon, Alfred

2014-05-01

This study explores the attitude of German psychiatrists in leading positions towards joint crisis plans and psychiatric advance directives. This topic was examined by contacting 473 medical directors of German psychiatric hospitals and departments. They were asked to complete a questionnaire developed by us. That form contained questions about the incidence and acceptance of joint crisis plans and psychiatric advance directives and previous experiences with them. 108 medical directors of psychiatric hospitals and departments responded (response rate: 22.8%). Their answers demonstrate that in their hospitals these documents are rarely used. Among the respondents, joint crisis plans are more accepted than psychiatric advance directives. There is a certain uncertainty when dealing with these instruments. Our main conclusion is that German psychiatry needs an intensified discussion on the use of instruments for patients to constitute procedures for future critical psychiatric events. For this purpose it will be helpful to collect more empirical data. Furthermore, the proposal of joint crisis plans in psychiatric hospitals and departments should be discussed as well as the possibility of consulting an expert during the preparation of a psychiatric advance directive.

Ambulatory surgery center joint ventures involving tax-exempt entities.

PubMed

Becker, S; Pristave, R J; McConnell, W

1999-01-01

This article provides an overview of the tax-exempt related issues for ambulatory surgery center joint ventures involving tax-exempt entities. The article analyzes the key points of analysis of the guidance released by the IRS, in particular General Counsel Memorandum 39862, Revenue Ruling 98-15, and Redlands Surgical Services v. Commissioner of the Internal Revenue Service. These key points include whether the venture results in private inurement to insiders and whether the venture furthers the charitable purposes of the tax-exempt entity. The article also provides practical guidance to analyze the documents and structure of the joint venture to ensure compliance with the IRS guidance. These practical considerations include, among other things, whether the charitable purposes of the tax-exempt entity are clearly expressed in the documents and whether the tax-exempt entity has sufficient control over the joint venture to ensure the charitable purposes are being adhered to.

The Multipurpose Black Hawk Utility Helicopter: Rotary-wing Versatility Required for U.S. Marine Corps Enhanced Company Operations

DTIC Science & Technology

2009-01-01

THE FOREGOING STATEMENT. QUOTATION FROM, ABSTRACTION FROM, OR REPRODUCTION OF ALL OR ANY PART OF THIS DOCVMENT IS PERMITTED PROVIDED PROPER...Capabilities and Limitations 7 AH-IW/Z Cobra’s Role in Support ofECO 8 CH-53E Super Stallion Capabilities and Limitations 9 CH-53E Super Stallion’s Role...of aircraft. Analysis of the roles and capabilities of the AH-IW Super Cobra, CH-53E Super Stallion , MV-22B Osprey, and the UH- IN Huey will identify

The role of lin-22, a hairy/enhancer of split homolog, in patterning the peripheral nervous system of C. elegans.

PubMed

Wrischnik, L A; Kenyon, C J

1997-08-01

In C. elegans, six lateral epidermal stem cells, the seam cells V1-V6, are located in a row along the anterior-posterior (A/P) body axis. Anterior seam cells (V1-V4) undergo a fairly simple sequence of stem cell divisions and generate only epidermal cells. Posterior seam cells (V5 and V6) undergo a more complicated sequence of cell divisions that include additional rounds of stem cell proliferation and the production of neural as well as epidermal cells. In the wild type, activity of the gene lin-22 allows V1-V4 to generate their normal epidermal lineages rather than V5-like lineages. lin-22 activity is also required to prevent additional neurons from being produced by one branch of the V5 lineage. We find that the lin-22 gene exhibits homology to the Drosophila gene hairy, and that lin-22 activity represses neural development within the V5 lineage by blocking expression of the posterior-specific Hox gene mab-5 in specific cells. In addition, in order to prevent anterior V cells from generating V5-like lineages, wild-type lin-22 gene activity must inhibit (directly or indirectly) at least five downstream regulatory gene activities. In anterior body regions, lin-22(+) inhibits expression of the Hox gene mab-5. It also inhibits the activity of the achaete-scute homolog lin-32 and an unidentified gene that we postulate regulates stem cell division. Each of these three genes is required for the expression of a different piece of the ectopic V5-like lineages generated in lin-22 mutants. In addition, lin-22 activity prevents two other Hox genes, lin-39 and egl-5, from acquiring new activities within their normal domains of function along the A/P body axis. Some, but not all, of the patterning activities of lin-22 in C. elegans resemble those of hairy in Drosophila.

Structural and spectroscopic studies of a rare non-oxido V(v) complex crystallized from aqueous solution

DOE PAGES

Leggett, Christina J.; Parker, Bernard F.; Teat, Simon J.; ...

2016-01-14

A “bare” V 5+ complex with glutaroimide-dioxime (H 3L), a ligand for uranium recovery from seawater, was synthesized from aqueous solution as Na[V(L) 2]2H 2O and the structure determined by x-ray diffraction. It is the first non-oxo V(v) complex that has been directly synthesized in and crystallized from aqueous solution.

Structural and spectroscopic studies of a rare non-oxido V(v) complex crystallized from aqueous solution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leggett, Christina J.; Parker, Bernard F.; Teat, Simon J.

A “bare” V 5+ complex with glutaroimide-dioxime (H 3L), a ligand for uranium recovery from seawater, was synthesized from aqueous solution as Na[V(L) 2]2H 2O and the structure determined by x-ray diffraction. It is the first non-oxo V(v) complex that has been directly synthesized in and crystallized from aqueous solution.

[A primary application and evaluation of temporomandibular joint replacement with stock prosthesis].

PubMed

Zhang, Xiao-hu; Chen, Min-jie; Qiu, Ya-ting; Yang, Chi

2012-06-01

To evaluate the effect of total joint replacement in treatment of temporomandibular joint(TMJ) osteoarthropathy with stock prostheses. Six female patients involving 10 joints (2 unilateral and 4 bilateral), with an average age of 59 years old, were involved in this study. Three patients (5 joints) were diagnosed as internal derangement in V stage depending on MRI, 3D-CT findings and clinical characteristics. The other 3 patients (5 joints) had histories of failed temporomandibular joint operation using costochondral graft or temporalis fascial flap. The maximal mouth opening was 1.9 cm on average (range, 1.0 to 2.9cm). All the joints were replaced with Biomet standard prosthesis under general anesthesia. The follow-up period was from 7 to 49 months (average, 17.5 months). All the operations were successfully performed. Heterotopic ossification happened in a bilateral case 1 year postoperatively. One patient with bilateral joint disease complained of severe uncomfortable feeling in the region of the ears and the temples, although there was no significant positive signs according to an ENT examination. Pain relief of the joint and mouth opening improvement were significant in 4 patients. No failure was noted secondary to infection or loosening of the prostheses. The occlusal relationship kept stable postoperatively in all cases. Total TMJ joint replacement with standard prosthesis is a good choice for TMJ reconstruction. It can significantly reduce joint pain and the mouth opening limitation resulted from osteoarthritis. Long-term result remains to be evaluated based on a long-term follow-up.

Assessment of articular disc displacement of temporomandibular joint with ultrasound.

PubMed

Razek, Ahmed Abdel Khalek Abdel; Al Mahdy Al Belasy, Fouad; Ahmed, Wael Mohamed Said; Haggag, Mai Ahmed

2015-06-01

To assess pattern of articular disc displacement in patients with internal derangement (ID) of temporomandibular joint (TMJ) with ultrasound. Prospective study was conducted upon 40 TMJ of 20 patients (3 male, 17 female with mean age of 26.1 years) with ID of TMJ. They underwent high-resolution ultrasound and MR imaging of TMJ. The MR images were used as the gold standard for calculating sensitivity, specificity, accuracy, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR), and negative likelihood ratio (NLR) of ultrasound for diagnosis of anterior or sideway displacement of the disc. The anterior displaced disc was seen in 26 joints at MR and 22 joints at ultrasound. The diagnostic efficacy of ultrasound for anterior displacement has sensitivity of 79.3 %, specificity of 72.7 %, accuracy of 77.5 %, PPV of 88.5 %, NPV of 57.1 %, PLR of 2.9 and NLR of 0.34. The sideway displacement of disc was seen in four joints at MR and three joints at ultrasound. The diagnostic efficacy of ultrasound for sideway displacement has a sensitivity of 75 %, specificity of 63.6 %, accuracy of 66.7 %, PPV of 42.8, NPV of 87.5 %, PLR of 2.06, and NLR of 0.39. We concluded that ultrasound is a non-invasive imaging modality used for assessment of anterior and sideway displacement of the articular disc in patients with ID of TMJ.

Biomechanical study of tarsometatarsal joint fusion using finite element analysis.

PubMed

Wang, Yan; Li, Zengyong; Zhang, Ming

2014-11-01

Complications of surgeries in foot and ankle bring patients with severe sufferings. Sufficient understanding of the internal biomechanical information such as stress distribution, contact pressure, and deformation is critical to estimate the effectiveness of surgical treatments and avoid complications. Foot and ankle is an intricate and synergetic system, and localized intervention may alter the functions to the adjacent components. The aim of this study was to estimate biomechanical effects of the TMT joint fusion using comprehensive finite element (FE) analysis. A foot and ankle model consists of 28 bones, 72 ligaments, and plantar fascia with soft tissues embracing all the segments. Kinematic information and ground reaction force during gait were obtained from motion analysis. Three gait instants namely the first peak, second peak and mid-stance were simulated in a normal foot and a foot with TMT joint fusion. It was found that contact pressure on plantar foot increased by 0.42%, 19% and 37%, respectively after TMT fusion compared with normal foot walking. Navico-cuneiform and fifth meta-cuboid joints sustained 27% and 40% increase in contact pressure at second peak, implying potential risk of joint problems such as arthritis. Von Mises stress in the second metatarsal bone increased by 22% at midstance, making it susceptible to stress fracture. This study provides biomechanical information for understanding the possible consequences of TMT joint fusion. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.

Neuromuscular interfacing: establishing an EMG-driven model for the human elbow joint.

PubMed

Pau, James W L; Xie, Shane S Q; Pullan, Andrew J

2012-09-01

Assistive devices aim to mitigate the effects of physical disability by aiding users to move their limbs or by rehabilitating through therapy. These devices are commonly embodied by robotic or exoskeletal systems that are still in development and use the electromyographic (EMG) signal to determine user intent. Not much focus has been placed on developing a neuromuscular interface (NI) that solely relies on the EMG signal, and does not require modifications to the end user's state to enhance the signal (such as adding weights). This paper presents the development of a flexible, physiological model for the elbow joint that is leading toward the implementation of an NI, which predicts joint motion from EMG signals for both able-bodied and less-abled users. The approach uses musculotendon models to determine muscle contraction forces, a proposed musculoskeletal model to determine total joint torque, and a kinematic model to determine joint rotational kinematics. After a sensitivity analysis and tuning using genetic algorithms, subject trials yielded an average root-mean-square error of 6.53° and 22.4° for a single cycle and random cycles of movement of the elbow joint, respectively. This helps us to validate the elbow model and paves the way toward the development of an NI.

Gastrocnemius tightness on joint angle and work of lower extremity during gait.

PubMed

You, Jia-Yuan; Lee, Hsin-Min; Luo, Hong-Ji; Leu, Chwan-Chin; Cheng, Pen-Gang; Wu, Shyi-Kuen

2009-11-01

Muscular tightness is a common clinical musculoskeletal disorder and is regarded as a predisposing factor for muscle injuries. In this study, a two-way mixed design ANOVA was applied to investigate the effects of the gastrocnemius tightness on the joint angle and joint work during walking. Twenty-two patients with muscular tightness of gastrocnemius muscle (<12 degrees of ankle dorsiflexion with knee extended) and 22 age- and gender-matched subjects with normal gastrocnemius flexibility (>15 degrees of ankle dorsiflexion with knee extended) participated in this study. The joint angle and work at hip, knee, and ankle joints during the stance phase were analyzed at two preset cadences of 100 steps/min and 140 steps/min. Significantly greater flexion angles at hip (P=0.025) and knee (P=0.001) were found in the tightness group at the time of maximal ankle dorsiflexion. Significantly less work generation at knee (P=0.034) and greater work absorption at ankle (P=0.024) were detected in the tightness group. The subjects with gastrocnemius tightness revealed a compensatory gait pattern, which included the changes in the joint angles and associated work productions. The potential disturbance of the knee control and strain injuries of plantar flexors might be crucial in the clinical considerations for subjects with gastrocnemius tightness.

40 CFR 22.22 - Evidence.

Code of Federal Regulations, 2010 CFR

2010-07-01

... § 22.19 (a), (e) or (f) to all parties at least 15 days before the hearing date, the Presiding Officer... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Evidence. 22.22 Section 22.22... PERMITS Hearing Procedures § 22.22 Evidence. (a) General. (1) The Presiding Officer shall admit all...

40 CFR 22.22 - Evidence.

Code of Federal Regulations, 2012 CFR

2012-07-01

... § 22.19 (a), (e) or (f) to all parties at least 15 days before the hearing date, the Presiding Officer... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Evidence. 22.22 Section 22.22... PERMITS Hearing Procedures § 22.22 Evidence. (a) General. (1) The Presiding Officer shall admit all...

40 CFR 22.22 - Evidence.

Code of Federal Regulations, 2011 CFR

2011-07-01

... § 22.19 (a), (e) or (f) to all parties at least 15 days before the hearing date, the Presiding Officer... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Evidence. 22.22 Section 22.22... PERMITS Hearing Procedures § 22.22 Evidence. (a) General. (1) The Presiding Officer shall admit all...

40 CFR 22.22 - Evidence.

Code of Federal Regulations, 2014 CFR

2014-07-01

... § 22.19 (a), (e) or (f) to all parties at least 15 days before the hearing date, the Presiding Officer... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Evidence. 22.22 Section 22.22... PERMITS Hearing Procedures § 22.22 Evidence. (a) General. (1) The Presiding Officer shall admit all...

40 CFR 22.22 - Evidence.

Code of Federal Regulations, 2013 CFR

2013-07-01

... § 22.19 (a), (e) or (f) to all parties at least 15 days before the hearing date, the Presiding Officer... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Evidence. 22.22 Section 22.22... PERMITS Hearing Procedures § 22.22 Evidence. (a) General. (1) The Presiding Officer shall admit all...

Impact extractive fracture of jointed steel plates of a bolted joint

NASA Astrophysics Data System (ADS)

Daimaruya, M.; Fujiki, H.; Ambarita, H.

2012-08-01

This study is concerned with the development of a fracture criterion for the impact fracture of jointed steel plates of a bolted joint used in a car body. For the accurate prediction of crash characteristics of car bodies by computer-aided engineering (CAE), it is also necessary to examine the behavior and fracture of jointed steel plates subjected to impact loads. Although the actual impact fracture of jointed steel plates of a bolted joint used in cars is complicated, for simplifying the problem it might be classified into the shear fracture and the extractive fracture of jointed steel plates. Attention is given to the extractive fracture of jointed steel plates in this study. The extractive behavior and fracture of three kinds of steel plates used for cars are examined in experiments and numerical simulations. The impact extraction test of steel plates jointed by a bolt is performed using the one-bar method, together with the static test. In order to understand the mechanism of extractive fracture process of jointed steel plates, numerical simulations by a FEM code LS-DYNA are also carried out. The obtained results suggest that a stress-based fracture criterion may be developed for the impact extractive fracture of jointed steel plates of a bolted joint used in a car body.

Translational and rotational knee joint stability in anterior and posterior cruciate-retaining knee arthroplasty.

PubMed

Lo, JiaHsuan; Müller, Otto; Dilger, Torsten; Wülker, Nikolaus; Wünschel, Markus

2011-12-01

This study investigated passive translational and rotational stability properties of the intact knee joint, after bicruciate-retaining bi-compartmental knee arthroplasty (BKA) and after posterior cruciate retaining total knee arthroplasty (TKA). Fourteen human cadaveric knee specimens were used in this study, and a robotic manipulator with six-axis force/torque sensor was used to test the joint laxity in anterior-posterior translation, valgus-varus, and internal-external rotation. The results show the knee joint stability after bicruciate-retaining BKA is similar to that of the native knee. On the other hand, the PCL-retaining TKA results in inferior joint stability in valgus, varus, external rotation, anterior and, surprisingly, posterior directions. Our findings suggest that, provided functional ligamentous structures, bicruciate-retaining BKA is a biomechanically attractive treatment for joint degenerative disease. Copyright © 2010 Elsevier B.V. All rights reserved.

Joint programmes in paediatric cardiothoracic surgery: a survey and descriptive analysis.

PubMed

DeCampli, William M

2011-12-01

Joint programmes, as opposed to regionalisation of paediatric cardiac care, may improve outcomes while preserving accessibility. We determined the prevalence and nature of joint programmes. We sent an online survey to 125 paediatric cardiac surgeons in the United States in November, 2009 querying the past or present existence of a joint programme, its mission, structure, function, and perceived success. A total of 65 surgeon responses from 65 institutions met the criteria for inclusion. Of the 65 institutions, 22 currently or previously conducted a joint programme. Compared with primary institutions, partner institutions were less often children's hospitals (p = 0.0004), had fewer paediatric beds (p = 0.005), and performed fewer cardiac cases (p = 0.03). Approximately 47% of partner hospitals performed fewer than 50 cases per year. The median distance range between hospitals was 41-60 miles, ranging from 5 to 1000 miles. Approximately 54% of partner hospitals had no surgeon working primarily on-site, and 31% of the programmes conducted joint conferences. Approximately 67% of the programmes limited the complexity of cases at the partner hospital, and 83% of the programmes had formal contracts between hospitals. Of the six programmes whose main mission was to increase referrals to the primary hospital, three were felt to have failed. Of the nine programmes whose mission was to increase regional quality, eight were felt to be successful. Joint programmes in paediatric cardiac surgery are common but are heterogeneous in structure and function. Programmes whose mission is to improve the quality of regional care seem more likely to succeed. Joint programmes may be a practical alternative to regionalisation to achieve better outcomes.

Joint Instability and Osteoarthritis

PubMed Central

Blalock, Darryl; Miller, Andrew; Tilley, Michael; Wang, Jinxi

2015-01-01

Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA). Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA. PMID:25741184

Joint instability and osteoarthritis.

PubMed

Blalock, Darryl; Miller, Andrew; Tilley, Michael; Wang, Jinxi

2015-01-01

Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA). Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA.

High‐resolution ultrasonography of the first metatarsal phalangeal joint in gout: a controlled study

PubMed Central

Wright, Stephen A; Filippucci, Emilio; McVeigh, Claire; Grey, Arthur; McCarron, Maura; Grassi, Walter; Wright, Gary D; Taggart, Allister J

2007-01-01

Objective To compare high‐resolution ultrasound (HRUS) with conventional radiography in the detection of erosions in the first metatarsophalangeal joints (1st MTPJs) of patients with gout and to identify the characteristic sonographic features of gout. Methods HRUS examination of the 1st MTPJs of both feet was performed by two independent sonographers. The presence of joint and soft‐tissue pathology was recorded. x Ray examination of the feet was performed on the same day and reported by the same radiologist. Results 39 male patients with gout and 22 age‐matched control subjects (14 with an inflammatory arthropathy and 8 disease free) were studied. The agreement on erosion between HRUS and x ray was poor, κ = 0.229 (non‐weighted), with McNemar's test being significant (p<0.001) indicating a large number of false negative x rays. 22 MTPJs in patients with gout had never been subjected to a clinical attack of acute gout. In these MTPJs, there were 10 erosions detected by HRUS and 3 erosions on x ray. HRUS features significantly more prevalent in the patients with gout were hard and soft tophus‐like lesions (p<0.01) and the double contour sign (p<0.01). Conclusions These data show that HRUS may assist in the management of gout in two ways: first, by aiding in the diagnosis by identifying the sonographic features that may be representative of the disease, and, second, by allowing the early detection of erosive joint damage and/or tophaceous deposits even in clinically silent joints. PMID:17185326

V/STOL flight simulation

NASA Technical Reports Server (NTRS)

1979-01-01

The requirements for a new research aircraft to provide in-flight V/STOL simulation were reviewed. The required capabilities were based on known limitations of ground based simulation and past/current experience with V/STOL inflight simulation. Results indicate that V/STOL inflight simulation capability is needed to aid in the design and development of high performance V/STOL aircraft. Although a new research V/STOL aircraft is preferred, an interim solution can be provided by use of the X-22A, the CH-47B, or the 4AV-8B aircraft modified for control/display flight research.

Modeling knee joint endoprosthesis mode of deformation

NASA Astrophysics Data System (ADS)

Skeeba, V. Yu; Ivancivsky, V. V.

2018-03-01

The purpose of the work was to define the efficient design of the endoprosthesis, working in a multiple-cycle loading environment. Methodology and methods: triangulated surfaces of the base contact surfaces of endoprosthesis butt elements have been created using the PowerShape and SolidWorks software functional environment, and the assemblies of the possible combinations of the knee joint prosthetic designs have been prepared. The mode of deformation modeling took place in the multipurpose program complex ANSYS. Results and discussion: as a result of the numerical modeling, the following data were obtained for each of the developed knee joint versions: the distribution fields of absolute (total) and relative deformations; equivalent stress distribution fields; fatigue strength coefficient distribution fields. In the course of the studies, the following efficient design assembly has been established: 1) Ti-Al-V alloy composite femoral component with polymer inserts; 2) ceramic liners of the compound separator; 3) a Ti-Al-V alloy composite tibial component. The fatigue strength coefficient for the femoral component is 4.2; for the femoral component polymer inserts is 1.2; for the ceramic liners of the compound separator is 3.1; for the tibial component is 2.7. This promising endoprosthesis structure is recommended for further design and technological development.

ACHP | News | National Trust/ACHP Joint Award Presented in Tulsa

Science.gov Websites

National Trust/ACHP Joint Award Presented in Tulsa The V-Site Restoration Project in Los Alamos, New Mexico Preservation/National Trust for Historic Preservation Award for Federal Partnerships in Historic Preservation ACHP-Trust award, click here. Posted October 27, 2008 Return to Top

[Lumbosacral facet joint stabilization: Mc Bride technique].

PubMed

Martínez, Ernesto De León; García, J Antonio Vázquez; Castillo, Pablo Atlitec

2008-01-01

We carried out a retrospective study of the clinical results of lumbosacral decompression with Mc Bride technique, in treatment of degenerative unstable lumbar stenosis. Three hundred and forty patients (180 male) were treated during May 1996 to May 2003. Mean age at surgery was 47 years old (22-85) with 3 to 8 years of follow up. All patients fulfilled clinical and image criteria for chronic lumbar pain due to degenerative lumbar stenosis and segmental instability that did not improve with conservative treatment. We found very good results in 114 patients (33.5%), good in 203 patients (59.7%), regular in 16 patients (4.7%), and poor in 6 patients (2%). The Mc Bride technique is based in interlaminar distraction and permits managing lumbar stenosis and arthrodesis of an unstable segment simultaneously. It diminishes compression in the foramen, maintains a position in extension, reduces facet joints subluxation and eliminates the strategic point of intervertebral mobility in facet joints. It allows immediate stabilization and later fusion by placing a bone block.

Experimental Investigation on Friction Stir Welding of Cryorolled AA2219 Aluminum Alloy Joints

NASA Astrophysics Data System (ADS)

Babu, K. Kamal; Panneerselvam, K.; Sathiya, P.; Haq, A. Noorul; Sundarrajan, S.; Mastanaiah, P.; Murthy, C. V. Srinivasa

2017-07-01

In this paper, experimental investigation on cryorolled aluminum AA2219-T87 plate by using friction stir welding (FSW) process is carried out. AA2219-T87 plates with a size of 200×100×22.4 mm were rolled and reduced to 12.2mm thickness (more than 45% of reduction in total thickness of the base material) at cryogenic temperature (operating temperature range -90--30∘C). The cryorolled (CR) plates have reduced grain size, improved hardness and increased corrosion resistance property compared with the uncryorolled AA2219-T87 plates. FSW joints of cryorolled AA2219-T87 plates were prepared using cylindrical threaded FSW tool pin profile. Mechanical and metallurgical behaviors of friction stir welded joints were analyzed and the effects of the FSW process parameters are discussed in this paper. The variation of microhardness in the FSW joint regions were correlated with the microstructure of FSW joints. Cryorolled plate and FSW joints were tested for corrosion resistance using potentiodynamic polarization test. FSW joints shows better result during the corrosion resistance analysis compared to base AA2219-T87. The X-ray diffraction (XRD) test results showed that fine α-Al grains with eutectic phase (Al2Cu) were present in the weld nugget (WN). The large clusters of strengthening precipitates were reduced in size and merged with the weld nugget portion.

Finite Element Modeling of Viscoelastic Behavior and Interface Damage in Adhesively Bonded Joints

DTIC Science & Technology

2012-01-01

eccentricity of the axis of a lap joint gives rise to transverse or peel stresses at the Report Documentation Page Form ApprovedOMB No. 0704-0188...Computers and Structures 29, 1011 (1988). 21 S. Roy and J. N. Reddy, Tire Sci. Technol. 16, 146 (1988). 22 S. Roy and J. N. Reddy, Intl. J. Numer

KSC-2011-4047

NASA Image and Video Library

2011-05-25

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, an adult osprey guards its young in a nest built on a platform in the Press Site parking lot. In the background is the 12,300-square-foot NASA logo painted on the side of the Vehicle Assembly Building (VAB). The VAB and Press Site are located at the Turn Basin in Launch Complex 39, making it an ideal osprey nesting place. The Merritt Island National Wildlife Refuge overlaps with Kennedy Space Center property and provides a habitat for many types of wildlife, including the osprey, and 330 species of birds. For information on the refuge, visit http://www.fws.gov/merrittisland/Index.html. Photo credit: NASA/Jack Pfaller

KSC-03pd0949

NASA Image and Video Library

2003-04-02

KENNEDY SPACE CENTER, FLA. -- A male osprey returns to its nest with a piece of fish in its talons for its mate. The nest was recently constructed on a speaker in the lower parking lot of the Press Site. Eggs have been sighted in the nest. The NASA logo seen in the background is on the nearby Vehicle Assembly Building. Known as a fish hawk, the osprey selects sites of opportunity, from trees and telephone poles to rocks or even flat ground. In the United States it is found from Alaska and Newfoundland to Florida and the Gulf Coast. Osprey nests are found throughout the Kennedy Space Center and surrounding Merritt Island National Wildlife Refuge.

The hindlimb in walking horses: 2. Net joint moments and joint powers.

PubMed

Clayton, H M; Hodson, E; Lanovaz, J L; Colborne, G R

2001-01-01

The objective of the study was to describe net joint moments and joint powers in the equine hindlimb during walking. The subjects were 5 sound horses. Kinematic and force data were collected synchronously and combined with morphometric information to determine net joint moments at each hindlimb joint throughout stance and swing. The results showed that the net joint moment was on the caudal/plantar side of all hindlimb joints at the start of stance when the limb was being actively retracted. It moved to the cranial/dorsal side around 24% stride at the hip and stifle and in terminal stance at the more distal joints. It remained on the cranial/dorsal side of all joints during the first half of swing to provide active limb protraction, then moved to the caudal/plantar aspect to reverse the direction of limb motion prior to ground contact. The hip joint was the main source of energy generation throughout the stride. It was assisted by the tarsal joint in both stance and swing phases and by the fetlock joint during the stance phase. The coffin joint acted as an energy damper during stance, whereas the stifle joint absorbed almost equal amounts of energy in the stance and swing phases. The coffin and fetlock joints absorbed energy as the limb was protracted and retracted during the swing phase, suggesting that their movements were driven by inertial forces. Future studies will apply these findings to detect changes in the energy profiles due to specific soft tissue injuries.

Multi-channel EEG-based sleep stage classification with joint collaborative representation and multiple kernel learning.

PubMed

Shi, Jun; Liu, Xiao; Li, Yan; Zhang, Qi; Li, Yingjie; Ying, Shihui

2015-10-30

Electroencephalography (EEG) based sleep staging is commonly used in clinical routine. Feature extraction and representation plays a crucial role in EEG-based automatic classification of sleep stages. Sparse representation (SR) is a state-of-the-art unsupervised feature learning method suitable for EEG feature representation. Collaborative representation (CR) is an effective data coding method used as a classifier. Here we use CR as a data representation method to learn features from the EEG signal. A joint collaboration model is established to develop a multi-view learning algorithm, and generate joint CR (JCR) codes to fuse and represent multi-channel EEG signals. A two-stage multi-view learning-based sleep staging framework is then constructed, in which JCR and joint sparse representation (JSR) algorithms first fuse and learning the feature representation from multi-channel EEG signals, respectively. Multi-view JCR and JSR features are then integrated and sleep stages recognized by a multiple kernel extreme learning machine (MK-ELM) algorithm with grid search. The proposed two-stage multi-view learning algorithm achieves superior performance for sleep staging. With a K-means clustering based dictionary, the mean classification accuracy, sensitivity and specificity are 81.10 ± 0.15%, 71.42 ± 0.66% and 94.57 ± 0.07%, respectively; while with the dictionary learned using the submodular optimization method, they are 80.29 ± 0.22%, 71.26 ± 0.78% and 94.38 ± 0.10%, respectively. The two-stage multi-view learning based sleep staging framework outperforms all other classification methods compared in this work, while JCR is superior to JSR. The proposed multi-view learning framework has the potential for sleep staging based on multi-channel or multi-modality polysomnography signals. Copyright © 2015 Elsevier B.V. All rights reserved.

Observation of β-delayed two-proton emission in the decay of 22Si

DOE PAGES

Xu, X. X.; Lin, C. J.; Sun, L. J.; ...

2017-01-19

The decay of the lightest nucleus with Tz=-3, 22Si, was studied by a silicon array. A charged-particle group at 5600 (70) keV in the decay-energy spectrum was identified experimentally as β-delayed two-proton emission from the isobaric analog state (IAS) of 22Al. Experimental results of the IAS fed by a superallowed Fermi transition were compared with our large-scale shell-model calculations. The ground-state mass of 22Si was obtained indirectly in the experiment for the first time. Two-proton separation energy for 22Si is deduced to be -108 (125) keV, which indicates that it is a very marginal candidate for two-proton ground-state emission.

Observation of β-delayed two-proton emission in the decay of 22Si

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, X. X.; Lin, C. J.; Sun, L. J.

The decay of the lightest nucleus with Tz=-3, 22Si, was studied by a silicon array. A charged-particle group at 5600 (70) keV in the decay-energy spectrum was identified experimentally as β-delayed two-proton emission from the isobaric analog state (IAS) of 22Al. Experimental results of the IAS fed by a superallowed Fermi transition were compared with our large-scale shell-model calculations. The ground-state mass of 22Si was obtained indirectly in the experiment for the first time. Two-proton separation energy for 22Si is deduced to be -108 (125) keV, which indicates that it is a very marginal candidate for two-proton ground-state emission.

Multi-joint postural behavior in patients with knee osteoarthritis.

PubMed

Turcot, Katia; Sagawa, Yoshimasa; Hoffmeyer, Pierre; Suvà, Domizio; Armand, Stéphane

2015-12-01

Previous studies have demonstrated balance impairment in patients with knee osteoarthritis (OA). Although it is currently accepted that postural control depends on multi-joint coordination, no study has previously considered this postural strategy in patients suffering from knee OA. The objectives of this study were to investigate the multi-joint postural behavior in patients with knee OA and to evaluate the association with clinical outcomes. Eighty-seven patients with knee OA and twenty-five healthy elderly were recruited to the study. A motion analysis system and two force plates were used to investigate the joint kinematics (trunk and lower body segments), the lower body joint moments, the vertical ground reaction force ratio and the center of pressure (COP) during a quiet standing task. Pain, functional capacity and quality of life status were also recorded. Patients with symptomatic and severe knee OA adopt a more flexed posture at all joint levels in comparison with the control group. A significant difference in the mean ratio was found between groups, showing an asymmetric weight distribution in patients with knee OA. A significant decrease in the COP range in the anterior-posterior direction was also observed in the group of patients. Only small associations were observed between postural impairments and clinical outcomes. This study brings new insights regarding the postural behavior of patients with severe knee OA during a quiet standing task. The results confirm the multi-joint asymmetric posture adopted by this population. Copyright © 2014 Elsevier B.V. All rights reserved.

Joint Attention Development in Low-risk Very Low Birth Weight Infants at Around 18 Months of Age.

PubMed

Yamaoka, Noriko; Takada, Satoshi

2016-10-18

The purpose of this study was to clarify the developmental characteristics of joint attention in very low birth weight (VLBW) infants with a low risk of complications. Section B of the Checklist for Autism in Toddlers (CHAT) was administered to 31 VLBW and 45 normal birth weight (NBW) infants aged 18-22 months, while the sessions were recorded with a video camera. A semi-structured observation scale was developed to assess infants' joint attention from the video footage, and was shown to be reliable. VLBW, compared to NBW, infants showed significantly poorer skills in 2 of 4 items on responding to joint attention, and in 6 of 10 items on initiating joint attention. VLBW infants need more clues in order to produce joint attention. The difficulty was attributed to insufficient verbal and fine motor function skills. Continuous follow-up evaluation is essential for both high-risk and low-risk VLBW infants and their parents.

Influence of Joint Angle on EMG-Torque Model During Constant-Posture, Torque-Varying Contractions.

PubMed

Liu, Pu; Liu, Lukai; Clancy, Edward A

2015-11-01

Relating the electromyogram (EMG) to joint torque is useful in various application areas, including prosthesis control, ergonomics and clinical biomechanics. Limited study has related EMG to torque across varied joint angles, particularly when subjects performed force-varying contractions or when optimized modeling methods were utilized. We related the biceps-triceps surface EMG of 22 subjects to elbow torque at six joint angles (spanning 60° to 135°) during constant-posture, torque-varying contractions. Three nonlinear EMG σ -torque models, advanced EMG amplitude (EMG σ ) estimation processors (i.e., whitened, multiple-channel) and the duration of data used to train models were investigated. When EMG-torque models were formed separately for each of the six distinct joint angles, a minimum "gold standard" error of 4.01±1.2% MVC(F90) resulted (i.e., error relative to maximum voluntary contraction at 90° flexion). This model structure, however, did not directly facilitate interpolation across angles. The best model which did so achieved a statistically equivalent error of 4.06±1.2% MVC(F90). Results demonstrated that advanced EMG σ processors lead to improved joint torque estimation as do longer model training durations.

The Analysis of Adhesively Bonded Advanced Composite Joints Using Joint Finite Elements

NASA Technical Reports Server (NTRS)

Stapleton, Scott E.; Waas, Anthony M.

2012-01-01

The design and sizing of adhesively bonded joints has always been a major bottleneck in the design of composite vehicles. Dense finite element (FE) meshes are required to capture the full behavior of a joint numerically, but these dense meshes are impractical in vehicle-scale models where a course mesh is more desirable to make quick assessments and comparisons of different joint geometries. Analytical models are often helpful in sizing, but difficulties arise in coupling these models with full-vehicle FE models. Therefore, a joint FE was created which can be used within structural FE models to make quick assessments of bonded composite joints. The shape functions of the joint FE were found by solving the governing equations for a structural model for a joint. By analytically determining the shape functions of the joint FE, the complex joint behavior can be captured with very few elements. This joint FE was modified and used to consider adhesives with functionally graded material properties to reduce the peel stress concentrations located near adherend discontinuities. Several practical concerns impede the actual use of such adhesives. These include increased manufacturing complications, alterations to the grading due to adhesive flow during manufacturing, and whether changing the loading conditions significantly impact the effectiveness of the grading. An analytical study is conducted to address these three concerns. Furthermore, proof-of-concept testing is conducted to show the potential advantages of functionally graded adhesives. In this study, grading is achieved by strategically placing glass beads within the adhesive layer at different densities along the joint. Furthermore, the capability to model non-linear adhesive constitutive behavior with large rotations was developed, and progressive failure of the adhesive was modeled by re-meshing the joint as the adhesive fails. Results predicted using the joint FE was compared with experimental results for various

Spacesuit mobility knee joints

NASA Technical Reports Server (NTRS)

Vykukal, H. C. (Inventor)

1979-01-01

Pressure suit mobility joints are for use in interconnecting adjacent segments of an hermetically sealed spacesuit in which low torques, low leakage and a high degree of reliability are required. Each of the joints is a special purpose joint characterized by substantially constant volume and low torque characteristics and includes linkages which restrain the joint from longitudinal distension and includes a flexible, substantially impermeable diaphragm of tubular configuration spanning the distance between pivotally supported annuli. The diaphragms of selected joints include rolling convolutions for balancing the joints, while various joints include wedge-shaped sections which enhance the range of motion for the joints.

Optical polarization observations in Hogg 22 and NGC 6204

NASA Astrophysics Data System (ADS)

Martínez, R.; Vergne, M. M.; Feinstein, C.

2004-06-01

We present new (UBVRI) multicolor linear polarimetric data for 22 of the brightest stars in the area of the open clusters Hogg 22 and NGC 6204 to study the properties of the ISM (interstellar medium) toward these clusters and between them. The new data were incorporated in our data set of previous observations (Waldhausen et al. \\cite{waldhausen}), resulting in 28 observed stars in the region. Our data yield for NGC 6204 a mean polarization percentage of Pλ_max˜1.8%, close to the polarization value produced by the ISM with normal efficiency (Pλ_max ˜ 5 EB-V) with a color excess of EB-V =0.51. Meanwhile for Hogg 22, located behind NGC 6204, the mean polarization is Pλ_max˜ 2.15%, lower than the expected value for the observed color excess of EB-V =0.68 (Forbes et al. 1996) and the average efficiency of polarization for the interstellar dust. The mean angle of the polarization vectors of Hogg 22 is θ=44.9 °, which agrees with the expected angle produce by dust particles aligned in the direction of the Galactic Plane (θ=48°), while for NGC 6204 a lower value, θ=33.7 °, was found. Therefore, we believe that Hogg 22 is depolarized by the same dust that is polarizing NGC 6204, due to different orientations of the dust particles (and magnetic fields) that polarize the starlight. Based on observations obtanined at Complejo Astronómico El Leoncito (CASLEO), operated under agreement between the CONICET and the National Universities of La Plata, Córdoba, and San Juan, Argentina.

4 CFR 22.22 - Accelerated and Small Claims Procedures [Rule 22].

Code of Federal Regulations, 2013 CFR

2013-01-01

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Code of Federal Regulations, 2010 CFR

2010-01-01

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Code of Federal Regulations, 2011 CFR

2011-01-01

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Code of Federal Regulations, 2012 CFR

2012-01-01

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Operation Joint Guard (SFOR) Bosnia. Assessment of Operational Stress and Adaptive Coping Mechanisms of Soldiers