Insulin Glargine 300 U/mL: A Review in Diabetes Mellitus.

PubMed

Blair, Hannah A; Keating, Gillian M

2016-03-01

Insulin glargine 300 U/mL (Toujeo(®)) is a long-acting basal insulin analogue approved for the treatment of diabetes mellitus. Insulin glargine 300 U/mL has a more stable and prolonged pharmacokinetic/pharmacodynamic profile than insulin glargine 100 U/mL (Lantus(®)), with a duration of glucose-lowering activity exceeding 24 h. In several 6-month phase III trials, insulin glargine 300 U/mL achieved comparable glycaemic control to that seen with insulin glargine 100 U/mL in patients with type 1 or type 2 diabetes, albeit with consistently higher daily basal insulin requirements. These improvements in glycaemic control were maintained during longer-term (12 months) treatment. Insulin glargine 300 U/mL was generally associated with a lower risk of nocturnal hypoglycaemia than insulin glargine 100 U/mL in insulin-experienced patients with type 2 diabetes, while the risk of nocturnal hypoglycaemia did not significantly differ between treatment groups in insulin-naïve patients with type 2 diabetes or in patients with type 1 diabetes. To conclude, once-daily subcutaneous insulin glargine 300 U/mL is an effective and generally well tolerated basal insulin therapy option for patients with type 1 or type 2 diabetes.

Observation of electrons with energy above 40 MeV at the altitudes 300-350 KM

NASA Astrophysics Data System (ADS)

Galper, A. M.; Grachev, V. M.; Dmitrenko, V. V.; Kirillov-Ugriumov, V. G.; Liakhov, V. A.; Rossomakhina, N. G.; Riumin, V. V.; Ulin, S. E.

The paper presents observations of electrons by the small, scintillator-gas Cerenkov gamma-telescope Elena-F at energies above 40 MeV and at altitudes of 300-350 km. Dependences of the electron fluxes at the 45-250 MeV and 60-460 MeV energy ranges from the vertical cutoff rigidity were measured, and for the equatorial region, the electron fluxes were found to be 193 plus or minus 32 and 160 plus or minus 30 e/sq m-s-sr, respectively, for the two energy ranges. The measured power law index of the differential energy spectrum 2.1 plus or minus 0.3. Results of observations in the region of the Brazil magnetic anomaly are discussed.

Delisting petition for 300-M saltstone (treated F006 sludge) from the 300-M liquid effluent treatment facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-04-04

This petition seeks exclusion for stabilized and solidified sludge material generated by treatment of wastewater from the 300-M aluminum forming and metal finishing processes. The waste contains both hazardous and radioactive components and is classified as a mixed waste. The objective of this petition is to demonstrate that the stabilized sludge material (saltstone), when properly disposed, will not exceed the health-based standards for the hazardous constituents. This petition contains sampling and analytical data which justify the request for exclusion. The results show that when the data are applied to the EPA Vertical and Horizontal Spread (VHS) Model, health-based standards formore » all hazardous waste constituents will not be exceeded during worst case operating and environmental conditions. Disposal of the stabilized sludge material in concrete vaults will meet the requirements pertaining to Waste Management Activities for Groundwater Protection at the Savannah River Site in Aiken, S.C. Documents set forth performance objectives and disposal options for low-level radioactive waste disposal. Concrete vaults specified for disposal of 300-M saltstone (treated F006 sludge) assure that these performance objectives will be met.« less

Switching to insulin glargine 300 U/mL: is duration of prior basal insulin therapy important?

PubMed

Bonadonna, Riccardo C; Renard, Eric; Cheng, Alice; Fritsche, Andreas; Cali, Anna; Melas-Melt, Lydie; Umpierrez, Guillermo E

2018-04-09

To assess the impact of duration of prior basal insulin therapy on study outcomes in people with type 2 diabetes mellitus receiving insulin glargine 300 U/mL (Gla-300) or insulin glargine 100 U/mL (Gla-100) for 6 months. A post hoc patient-level meta-analysis of data from the EDITION 1 and 2 studies. Outcomes included: HbA 1c , percentage of participants with ≥1 confirmed or severe hypoglycaemic event at night (00:00-05:59 h) or any time (24 h), and body weight change. Data were analysed according to duration of prior basal insulin use: >0-≤2 years, >2-≤5 years, >5 years. This meta-analysis included 1618 participants. HbA 1c change from baseline to month 6 was comparable between Gla-300 and Gla-100 groups, regardless of duration of prior basal insulin therapy. The lower risk with Gla-300 versus Gla-100 of ≥1 confirmed (≤3.9 mmol/L [≤70 mg/dL]) or severe hypoglycaemic event, at night or any time (24 h), was unaffected by duration of prior basal insulin therapy. Similarly, weight change was unaffected by duration of prior basal insulin therapy. Switching to Gla-300 from other basal insulin therapies provided comparable glycaemic control with lower risk of hypoglycaemia versus Gla-100, regardless of duration of prior basal insulin therapy. Copyright © 2018. Published by Elsevier B.V.

Comparative Study Using 100–300 Versus 300–500 μm Microspheres for Symptomatic Patients Due to Enlarged-BPH Prostates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gonçalves, Octavio Meneghelli, E-mail: octaviogalvao@hotmail.com; Carnevale, Francisco Cesar, E-mail: francisco.carnevale@criep.com.br; Moreira, Airton Mota, E-mail: motamoreira@gmail.com

PurposeThe purpose of the study was to compare safety and efficacy outcomes following prostate artery embolization (PAE) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) with 100–300 versus 300–500 μm tris-acryl gelatin microspheres.Materials and MethodsPatients were prospectively treated between August 2011 and June 2013 to receive PAE with 100–300 μm (group A) or 300–500 μm (group B) tris-acryl gelatin microspheres. Patients were followed for a minimum of 12 months and were assessed for changes in International Prostate Symptom Score (IPSS), quality of life (QoL) index, prostate volume determined by magnetic resonance imaging, serum prostate specific antigen (PSA),more » and maximum urine flow rate (Q{sub max}), as well as any treatment-related adverse events.ResultsFifteen patients were included in each group, and PAE was technically successful in all cases. Both groups experienced significant improvement in mean IPSS, QoL, prostate volume, PSA, and Q{sub max} (p < 0.05 for all). The differences observed between the two groups included a marginally insignificant more adverse events (p = 0.066) and greater mean serum PSA reduction at 3 months of follow-up (p = 0.056) in group A.ConclusionsBoth 100–300 and 300–500 μm microspheres are safe and effective embolic agents for PAE to treat LUTS-related to BPH. Although functional and imaging outcomes did not differ significantly following use of the two embolic sizes, the greater incidence of adverse events with 100–300 μm microspheres suggests that 300–500 μm embolic materials may be more appropriate.« less

Study on the parameters of the scanning system for the 300 keV electron accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leo, K. W.; Chulan, R. M., E-mail: leo@nm.gov.my; Hashim, S. A.

2016-01-22

This paper describes the method to identify the magnetic coil parameters of the scanning system. This locally designed low energy electron accelerator with the present energy of 140 keV will be upgraded to 300 keV. In this accelerator, scanning system is required to deflect the energetic electron beam across a titanium foil in vertical and horizontal direction. The excitation current of the magnetic coil is determined by the energy of the electron beam. Therefore, the magnetic coil parameters must be identified to ensure the matching of the beam energy and excitation coil current. As the result, the essential parameters ofmore » the effective lengths for X-axis and Y-axis have been found as 0.1198 m and 0.1134 m and the required excitation coil currents which is dependenton the electron beam energies have be identified.« less

Station Keeping Results for Seabotix vLBV300 Underwater Vehicle near Newport, OR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hollinger, Geoffrey

This data set presents results testing the station keeping abilities of a tethered Seabotix vLBV300 underwater vehicle equipped with an inertial navigation system. These results are from an offshore deployment on April 20, 2016 off the coast of Newport, OR (44.678 degrees N, 124.109 degrees W). During the mission period, the sea state varied between 3 and 4, with an average significant wave height of 1.6 m. The vehicle utilizes an inertial navigation system based on a Gladiator Landmark 40 IMU coupled with a Teledyne Explorer Doppler Velocity Log to perform station keeping at a desired location and orientation.

Disintegration of 12C nuclei by 700-1500 MeV photons

NASA Astrophysics Data System (ADS)

Nedorezov, V.; D'Angelo, A.; Bartalini, O.; Bellini, V.; Capogni, M.; Casano, L. E.; Castoldi, M.; Curciarello, F.; De Leo, V.; Didelez, J.-P.; Di Salvo, R.; Fantini, A.; Franco, D.; Gervino, G.; Ghio, F.; Giardina, G.; Girolami, B.; Giusa, A.; Lapik, A.; Levi Sandri, P.; Mammoliti, F.; Mandaglio, G.; Manganaro, M.; Moricciani, D.; Mushkarenkov, A.; Pshenichnov, I.; Randieri, C.; Rudnev, N.; Russo, G.; Schaerf, C.; Sperduto, M.-L.; Sutera, M.-C.; Turinge, A.; Vegna, V.; Zonta, I.

2015-08-01

Disintegration of 12C nuclei by tagged photons of 700-1500 MeV energy at the GRAAL facility has been studied by means of the LAGRANγE detector with a wide angular acceptance. The energy and momentum distributions of produced neutrons and protons as well as their multiplicity distributions were measured and compared with corresponding distributions calculated with the RELDIS model based on the intranuclear cascade and Fermi break-up models. It was found that eight fragments are created on average once per about 100 disintegration events, while a complete fragmentation of 12C into 12 nucleons is observed typically only once per 2000 events. Measured multiplicity distributions of produced fragments are well described by the model. The measured total photoabsorption cross section on 12C in the same energy range is also reported.

In vitro and in vivo study of additive manufactured porous Ti6Al4V scaffolds for repairing bone defects

NASA Astrophysics Data System (ADS)

Li, Guoyuan; Wang, Lei; Pan, Wei; Yang, Fei; Jiang, Wenbo; Wu, Xianbo; Kong, Xiangdong; Dai, Kerong; Hao, Yongqiang

2016-09-01

Metallic implants with a low effective modulus can provide early load-bearing and reduce stress shielding, which is favorable for increasing in vivo life-span. In this research, porous Ti6Al4V scaffolds with three pore sizes (300~400, 400~500, and 500~700 μm) were manufactured by Electron Beam Melting, with an elastic modulus range of 3.7 to 1.7 GPa. Cytocompatibility in vitro and osseointegration ability in vivo of scaffolds were assessed. hBMSCs numbers increased on all porous scaffolds over time. The group with intended pore sizes of 300 to 400 μm was significantly higher than that of the other two porous scaffolds at days 5 and 7. This group also had higher ALP activity at day 7 in osteogenic differentiation experiment. The scaffold with pore size of 300 to 400 μm was implanted into a 30-mm segmental defect of goat metatarsus. In vivo evaluations indicated that the depth of bone ingrowth increased over time and no implant dislocation occurred during the experiment. Based on its better cytocompatibility and favorable bone ingrowth, the present data showed the capability of the additive manufactured porous Ti6Al4V scaffold with an intended pore size of 300 to 400 μm for large segmental bone defects.

Clinical Pharmacokinetics and Pharmacodynamics of Insulin Glargine 300 U/mL.

PubMed

Clements, Jennifer N; Threatt, Tiffaney; Ward, Eileen; Shealy, Kayce M

2017-05-01

Concentrated insulin analogs have recently been approved and are available for clinical use in the management of diabetes mellitus. One new product is insulin glargine U-300 (Sanofi), a basal concentrated insulin of 300 U/mL. Several studies have been conducted and completed evaluating blood samples for the pharmacokinetics of insulin glargine U-300 and euglycemic clamp procedures for the pharmacodynamics. This concentrated insulin has a low within-day variability and high day-to-day reproducibility, allowing for a more constant and prolonged duration of action, compared with insulin glargine U-100 (100 U/mL). Insulin glargine U-300 is equally effective, when compared with insulin glargine U-100 for glycemic control in patients with type 1 and 2 diabetes mellitus. Insulin glargine U-300 has a similar efficacy profile to insulin glargine U-100 for glycemic control, yet with lower rates of nocturnal and severe hypoglycemia. Insulin glargine U-300 can be considered an acceptable basal insulin for patients with type 1 and 2 diabetes mellitus, and it has a potential role among patients who are naïve to insulin therapy or require titration of basal insulin. Titration of insulin glargine U-300 would result in less volume and a lower risk of hypoglycemia, compared with insulin glargine U-100. This article evaluates and summarizes the pharmacokinetics and pharmacodynamics of insulin glargine U-300, for patients with type 1 or 2 diabetes mellitus, and summarizes its application to clinical practice.

The 300 mA SRF ERL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ben-Zvi, Ilan

Energy Recovery Linacs (ERL) are important for a variety of applications, from high-power Free-Electron Lasers (FEL) to polarized-electron polarized-proton colliders. The ERL current is arguably the most important characteristic of ERLs for such applications. With that in mind, the Collider-Accelerator Department at Brookhaven National Laboratory embarked on the development of a 300 mA ERL to serve as an R and D test-bed for high-current ERL technologies. These include high-current, extremely well damped superconducting accelerating cavities, high-current superconducting laser-photocathode electron guns and high quantum-efficiency photocathodes. In this presentation I will cover these ERL related developments.

Continued improvement of perioperative, pathological and continence outcomes during 700 robot-assisted radical prostatectomies.

PubMed

Zorn, Kevin C; Wille, Mark A; Thong, Alan E; Katz, Mark H; Shikanov, Sergey A; Razmaria, Aria; Gofrit, Ofer N; Zagaja, Gregory P; Shalhav, Arieh L

2009-08-01

Several robot-assisted radical prostatectomy (RARP) series have reviewed the impact of the initial learning curve on perioperative outcomes. However, little is known about the impact of experience on urinary and sexual outcomes. Herein, we review the perioperative, pathological and functional outcomes of our initial 700 consecutive procedures with at least 1 year follow up. From 2003-2006, 700 consecutive men underwent RARP at a single, academic institution. Perioperative data and pathologic outcomes were prospectively collected. Validated, UCLA-PCI-SF36v2 quality-of-life questionnaires were also obtained at 1, 3, 6 and 12 months following surgery. Outcomes between groups (cases 1-300, 301-500, and 501-700) were compared. Mean operative time (OT) and blood loss significantly decreased during the experience (286, 198, 190 min; p or=7 in 24%, 40%, 44%; p v2 questionnaire in the initial group. Continence rates improved to 93% and 75%, respectively, for cases 501-700 (p v2. No significant differences in sexual function were noted with increased experience. A prolonged learning curve is observed for EBL, OT and pT2-PSM. In addition, to the best of our knowledge, this is first series demonstrating a continued improvement in urinary continence with increased RARP experience.

Hydrocoil Turbine Performance at 3 m, 4 m, and 5 m Head Analysis Using Computational Fluid Dynamics Method

NASA Astrophysics Data System (ADS)

Luthfie, A. A.; Pratiwi, S. E.; Hidayatulloh, P.

2018-03-01

Indonesia is a country which has abundant renewable energy resources, comprises of water, solar, geothermal, wind, bioenergy, and ocean energy. Utilization of water energy through MHP is widely applied in remote areas in Indonesia. This utilization requires a water-converting device known as a water turbine. Rosefsky (2010) developed a water turbine known as the Hydrocoil turbine. This turbine is an axial turbine which is a modification of screw turbine. This turbine has a pitch length that decreases in the direction of the water flow and is able to work at relatively low water flow and head. The use of Hydrocoil turbine has not been widely applied in Indonesia, therefore this research is focused on analyzing the performance of Hydrocoil turbine. The analysis was performed using Computational Fluid Dynamics (CFD) method. Hydrocoil turbine performance analysis was performed at 3 m, 4 m, and 5 m head respectively as well as rotational speed variations of 100 rpm, 300 rpm, 500 rpm, 700 rpm, 900 rpm, 1,100 rpm, 1,300 rpm, 1,500 rpm, 1,700 rpm, and 1,900 rpm. Based on simulation result, the largest power generated by the turbine at 3 m head is 1,134.06 W, while at 4 m and 5 m are 1,722.39 W and 2,231.49 W respectively. It is also found that the largest turbine’s efficiency at 3 m head is 93.22% while at 4 m and 5 m head are 94.6% and 89.88% respectively. The result also shows that the larger the head the greater the operational rotational speed range.

In situ Investigation of Methane Dry Reforming on M-CeO 2(111) {M= Co, Ni, Cu} Surfaces: Metal-Support Interactions and the activation of C-H bonds at Low Temperature

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rodriguez, Jose A.; Liu, Zongyuan; Lustemberg, Pablo

Studies with a series of M-CeO 2(111) {M= Co, Ni, Cu} surfaces indicate that metal-oxide interactions can play a very important role for the activation of methane and its reforming with CO 2 at relatively low temperatures (600-700 K). Among the systems examined, Co-CeO 2(111) exhibits the best performance and Cu-CeO 2(111) has negligible activity. Experiments using ambient pressure XPS indicate that methane dissociates on Co-CeO2(111), at temperatures as low as 300 K, generating CH x and CO x species on the catalyst surface. The results of density-functional calculations show a reduction in the methane activation barrier from 1.07 eVmore » on Co(0001) to 0.87 eV on Co 2+/CeO 2(111), and to only 0.05 eV on Co 0/CeO 2-x(111). At 700 K, under methane dry reforming conditions, CO 2 dissociates on the oxide surface and a catalytic cycle is established without coke deposition. In conclusion, a significant part of the CH x formed on the Co 0/CeO 2-x (111) catalyst recombines to yield ethane or ethylene.« less

In situ Investigation of Methane Dry Reforming on M-CeO 2(111) {M= Co, Ni, Cu} Surfaces: Metal-Support Interactions and the activation of C-H bonds at Low Temperature

DOE PAGES

Rodriguez, Jose A.; Liu, Zongyuan; Lustemberg, Pablo; ...

2017-08-16

Studies with a series of M-CeO 2(111) {M= Co, Ni, Cu} surfaces indicate that metal-oxide interactions can play a very important role for the activation of methane and its reforming with CO 2 at relatively low temperatures (600-700 K). Among the systems examined, Co-CeO 2(111) exhibits the best performance and Cu-CeO 2(111) has negligible activity. Experiments using ambient pressure XPS indicate that methane dissociates on Co-CeO2(111), at temperatures as low as 300 K, generating CH x and CO x species on the catalyst surface. The results of density-functional calculations show a reduction in the methane activation barrier from 1.07 eVmore » on Co(0001) to 0.87 eV on Co 2+/CeO 2(111), and to only 0.05 eV on Co 0/CeO 2-x(111). At 700 K, under methane dry reforming conditions, CO 2 dissociates on the oxide surface and a catalytic cycle is established without coke deposition. In conclusion, a significant part of the CH x formed on the Co 0/CeO 2-x (111) catalyst recombines to yield ethane or ethylene.« less

Simulation of planar single-gate Si tunnel FET with average subthreshold swing of less than 60 mV/decade for 0.3 V operation

NASA Astrophysics Data System (ADS)

Kukita, Kentaro; Uechi, Tadayoshi; Shimokawa, Junji; Goto, Masakazu; Yokota, Yoshinori; Kawanaka, Shigeru; Tanamoto, Tetsufumi; Tanimoto, Hiroyoshi; Takagi, Shinichi

2018-04-01

Planar single-gate (SG) silicon (Si) tunnel field effect transistors (TFETs) are attracting interest for ultra-low voltage operation and CMOS applications. For the achievement of subthreshold swing (S.S.) less than thermal limit of Si MOSFETs (S.S. = 60 mV/decade at 300 K), previous studies have proposed the formation of a pocket region, which needs very difficult implantation process. In this work, a planar SG Si TFET without pocket was proposed by using the technology computer-aided design (TCAD) simulations. An average S.S. of less than 60 mV/decade for 0.3 V (= V gs = V ds) operation was obtained. It is found that both low average S.S. (= 27.8 mV/decade) and high on-current I on (= 3.8 µA/µm) are achieved without pocket doping by scaling the equivalent oxide thickness (EOT) and increasing the gate-to-source overlap length L ov.

Atomic Number Dependence of Hadron Production at Large Transverse Momentum in 300 GeV Proton--Nucleus Collisions

DOE R&D Accomplishments Database

Cronin, J. W.; Frisch, H. J.; Shochet, M. J.; Boymond, J. P.; Mermod, R.; Piroue, P. A.; Sumner, R. L.

1974-07-15

In an experiment at the Fermi National Accelerator Laboratory we have compared the production of large transverse momentum hadrons from targets of W, Ti, and Be bombarded by 300 GeV protons. The hadron yields were measured at 90 degrees in the proton-nucleon c.m. system with a magnetic spectrometer equipped with 2 Cerenkov counters and a hadron calorimeter. The production cross-sections have a dependence on the atomic number A that grows with P{sub 1}, eventually leveling off proportional to A{sup 1.1}.

Anuglar distribution of shower particles produced in the collisions of 20-GeV/c and 300-GeV negative pions with emulsion nuclei

NASA Technical Reports Server (NTRS)

Kim, C. O.; Kim, S. N.; Park, I. G.; Yoon, C. S.

1983-01-01

For 435 accelerator produced antipions jets of 20 GeV/c and 300 GeV, in nuclear emulsion, eta(theta)'s have been individually calculated for each jet, where eta(theta) is a kinematic parameter introduced in order to approximate the LS (laboratory system) rapidity, eta = arctan h (beta cos theta). By taking further averages by dividing the samples into groupings of the LS energy E sub pi = m cos h eta sub pi N sub h, the number of heavy prongs with LS velocity beta 0.7, and n , the number of charged shower particles with LS velocity beta 0.7, much less than eta (theta) much greater than are obtained. By use of the KNO (Koba-Nielsen-Olesen) scaling variable, xi = n sub s/,n sub s. good fit is found of data to regression function.

Insulin glargine 300 units/mL: A new basal insulin product for diabetes mellitus.

PubMed

Clements, Jennifer N; Bello, Larkin

2016-03-15

The pharmacokinetics, efficacy, and safety of U-300 insulin glargine for the management of diabetes are reviewed. U-300 (300 units/mL) insulin glargine is a long-acting basal insulin with low within-day variability, high day-to-day reproducibility, longer duration, and constant pharmacokinetic profile compared with U-100 (100 units/mL) insulin glargine. U-300 was evaluated in six randomized, active-comparator, open-label, Phase III clinical studies (EDITION trials) among patients with type 1 or 2 diabetes. The primary endpoint for all EDITION studies was the reduction in glycosylated hemoglobin from baseline to six months. Safety endpoints included confirmed or nocturnal hypoglycemia between week 9 and month 6 and the change in weight from baseline. For hypoglycemic episodes, U-300 insulin glargine was superior to U-100 insulin glargine when comparing the risk of hypoglycemia. U-300 insulin glargine is supplied in a prefilled device (for safety purposes) and packaged in boxes of three or five pens. It is still early to determine the role of U-300 insulin glargine in diabetes management. When compared with U-100 insulin glargine, U-300 insulin glargine appeared to be associated with a lower risk of hypoglycemia and nocturnal hypoglycemia, most likely due to its pharmacokinetics. The wholesale average cost of U-300 insulin glargine is $335.48 per box of three pens. The efficacy outcomes of U-300 insulin glargine were similar to those of U-100 insulin glargine, but the constant pharmacokinetic profile and longer duration of action of U-300 insulin glargine may help certain patients with type 1 or type 2 diabetes achieve better glycemic control. Copyright © 2016 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

New in situ Aerosol Spectral Optical Measurements over 300-700 nm, Extinction and Total Absorption, Paired with Absorption from Water- and Methanol-soluble Aerosol Extracts

NASA Astrophysics Data System (ADS)

Jordan, C. E.; Stauffer, R. M.; Lamb, B.; Novak, M. G.; Mannino, A.; Hudgins, C.; Thornhill, K. L., II; Crosbie, E.; Winstead, E.; Anderson, B.; Martin, R.; Shook, M.; Ziemba, L. D.; Beyersdorf, A. J.; Corr, C.

2017-12-01

A new in situ spectral aerosol extinction instrument (custom built, SpEx) built to cover the 300-700 nm range at 1 nm spectral resolution and temporal resolution of 4 minutes was deployed on the top deck ( 10 m above the water surface) of the R/V Onnuri during the KORUS-OC research cruise around South Korea in spring 2016. This new instrument was one component of a suite of in situ aerosol optical measurements that included 3-visible-wavelength scattering (Airphoton IN101 Nephelometer, at 450, 532, & 632 nm) and absorption (Brechtel Tricolor Absorption Photometer Model 2901, at 467, 528, & 652 nm) with sub-minute temporal resolution; two sets of filters (Teflon and glass fiber, both collected over 3 hour daytime and 12 hour overnight intervals) to provide aerosol absorption spectra over the same wavelength range as SpEx. The glass fiber filters were placed in the center of an integrating sphere (Labsphere DRA-CA-30) attached to a dual beam spectrophotometer (Cary 100 Bio UV-Visible Spectrophotometer) to measure total aerosol absorption spectra via an established method used by the ocean color community to obtain absorption spectra from particles suspended in sea water. Adapting this methodology for atmospheric aerosol measurements provides a new avenue to obtain spectral total aerosol absorption, particularly useful for expanding in situ measurement capabilities into the UV range. The Teflon filters were cut in half with one half extracted in deionized water and the other half extracted in methanol. The solutions were filtered and injected into a liquid waveguide capillary cell (World Precision Instruments LWCC-3100, 100 cm pathlength) to measure the absorption spectra for each solution. In addition, the water extracts were measured via ion chromatography (Dionex ICS-3000 Ion Chromatography System) to obtain water-soluble inorganic ion concentrations, as well as via aerosol mass spectrometry (Aerodyne Research, Inc. HR-ToF High Resolution Aerosol Mass Spectrometer

Compatibility of an Ultraselective Microcatheter and Epirubicin Loaded 300-500-μm DC Bead in Ex Vivo Study.

PubMed

Fukuoka, Yasushi; Tanaka, Toshihiro; Nishiofuku, Hideyuki; Sato, Takeshi; Kichikawa, Kimihiko

2015-10-01

The purpose of this study is to examine whether epirubicin loaded DC Bead 300-500 μm in size can pass through a 1.8-Fr ultraselective microcatheter in ex vivo study. Epirubicin (25 mg/1 mL) loaded 100-300 and 300-500 μm DC Bead were tested. Both sizes were diluted 5, 10, and 30 times using contrast material. Ultraselective microcatheter with the outer diameter of 1.8 Fr and the inner diameter of .017 inch (431.8 μm) was used. The diluted DC Bead was injected at a speed of 1 mL/min, and the pressure was continuously measured. The microspheres' shapes after ejection were observed by a stereomicroscope. The maximum pressure of contrast material alone was 8.40 ± 0.21 psi. The maximum pressure in 5, 10, and 30 times dilution groups of 100-300 μm were 9.67 ± 1.18, 9.25 ± 0.25, and 9.71 ± 0.28 psi, respectively, whereas 21.10 ± 10.2, 10.48 ± 2.14, 10.09 ± 0.37 psi, respectively in 300-500 μm groups. The maximum pressure in 5 times dilution group of 300-500 μm was significantly higher than the other groups (P < 0.05). In 300-500 μm, 4 of 10 measurements showed high pressure over 24 psi (the maximum value was 43.5 psi) in 5 times dilution group, whereas in 10 times and 30 times dilution groups, all measurements showed less than 12 psi. No damages of microspheres were found. Epirubicin loaded DC Bead 300-500 μm in size can pass through a 1.8-Fr ultraselective microcatheter. To avoid high resistance due to microspheres' aggregation, dilution more than 10 times is needed.

Mechanisms of antimony adsorption onto soybean stover-derived biochar in aqueous solutions.

PubMed

Vithanage, Meththika; Rajapaksha, Anushka Upamali; Ahmad, Mahtab; Uchimiya, Minori; Dou, Xiaomin; Alessi, Daniel S; Ok, Yong Sik

2015-03-15

Limited mechanistic knowledge is available on the interaction of biochar with trace elements (Sb and As) that exist predominantly as oxoanions. Soybean stover biochars were produced at 300 °C (SBC300) and 700 °C (SBC700), and characterized by BET, Boehm titration, FT-IR, NMR and Raman spectroscopy. Bound protons were quantified by potentiometric titration, and two acidic sites were used to model biochar by the surface complexation modeling based on Boehm titration and NMR observations. The zero point of charge was observed at pH 7.20 and 7.75 for SBC300 and SBC700, respectively. Neither antimonate (Sb(V)) nor antimonite (Sb(III)) showed ionic strength dependency (0.1, 0.01 and 0.001 M NaNO3), indicating inner sphere complexation. Greater adsorption of Sb(III) and Sb(V) was observed for SBC300 having higher -OH content than SBC700. Sb(III) removal (85%) was greater than Sb(V) removal (68%). Maximum adsorption density for Sb(III) was calculated as 1.88 × 10(-6) mol m(-2). The Triple Layer Model (TLM) successfully described surface complexation of Sb onto soybean stover-derived biochar at pH 4-9, and suggested the formation of monodentate mononuclear and binuclear complexes. Spectroscopic investigations by Raman, FT-IR and XPS further confirmed strong chemisorptive binding of Sb to biochar surfaces. Copyright © 2014 Elsevier Ltd. All rights reserved.

Microstructure and mechanical properties of quenched and tempered 300M steel

NASA Technical Reports Server (NTRS)

Youngblood, J. L.; Raghavan, M.

1978-01-01

Type 300M steel, which is being used for the landing gear on the space shuttle orbiter, was subjected to a wide range of quenched and tempered heat treatments. The plane-strain fracture toughness and the tensile ultimate and yield strengths were evaluated. Cryogenic mechanical properties were obtained for conventionally heat-treated steel. The microstructure of all heat-treated test coupons was studied both optically and by transmission electron microscopy. Fracture surfaces were studied by means of scanning electron microscopy. Results indicate that substantial improvement in toughness with no loss in strength can be accomplished in quenched and tempered steel by austenitizing at 1255 K or higher. Low fracture toughness in conventionally austenitized 300M steel (1144 K) appears to be caused by undissolved precipitates, seen both in the submicrostructure and on the fracture surface, which promote failure by quasi-cleavage. The precipitates appeared to dissolve in the range 1200 to 1255 K.

Insulin glargine 300 units/mL: a guide for healthcare professionals involved in the management of diabetes.

PubMed

Strong, Jodi; Kruger, Davida; Novak, Lucia

2017-04-01

Insulin glargine 300 units/mL: Insulin glargine 300 units/mL (Gla-300) is a formulation of insulin glargine that delivers the same number of insulin units in one-third of the injectable volume of insulin glargine 100 units/mL (Gla-100). Glucose control: Recently approved in the United States and in Europe for use in type 1 and type 2 diabetes, Gla-300 has a more constant and evenly distributed glucose-lowering effect compared with Gla-100, with a duration of action beyond 24 hours and lower within-day and between-day intra-individual variability in blood glucose levels. These benefits translate into predictable and sustained glucose control from a once-daily injection, with potential for fewer hypoglycemia episodes and less weight gain. Case studies are presented to highlight the potential clinical benefits and considerations associated with initiating treatment with Gla-300 in people with type 1 and type 2 diabetes.

Kilovoltage radiotherapy for companion animals: dosimetric comparison of 300 kV, 450 kV, and 6 MV X-ray beams.

PubMed

Seo, Jaehyeon; Son, Jaeman; Cho, Yeona; Park, Nohwon; Kim, Dong Wook; Kim, Jinsung; Yoon, Myonggeun

2018-04-12

Radiotherapy for the treatment of cancer in companion animals is currently administered using megavoltage X-ray machines. Because these machines are expensive, most animal hospitals do not perform radiotherapy. This study evaluated the ability of relatively inexpensive kilovoltage X-ray machines to treat companion animals. A simulation study based on a treatment planning system was performed for tumors of the brain (non-infectious meningoencephalitis), nasal cavity (malignant nasal tumors), forefoot (malignant muscular tumors), and abdomen (malignant intestinal tumors). The results of kilovoltage (300 kV and 450 kV) and megavoltage (6 MV) X-ray beams were compared. Whereas 300 kV and 6 MV X-ray beams provided optimal radiation dose homogeneity and conformity, respectively, for brain tumors, 6 MV X-rays provided optimal homogeneity and radiation conformity for nasal cavity, forefoot and abdominal tumors. Although megavoltage X-ray beams provided better radiation dose distribution in most treated animals, the differences between megavoltage and kilovoltage X-ray beams were relatively small. The similar therapeutic effects of kilovoltage and 6 MV X-ray beams suggest that kilovoltage X-ray beams may be effective alternatives to megavoltage X-ray beams in treating cancers in companion animals.

Microstructure and mechanical properties of titanium aluminum carbides neutron irradiated at 400–700 °C

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ang, Caen; Parish, Chad M.; Shih, Chunghao

2017-02-23

Here, this work reports the first mechanical properties of Ti 3AlC 2-Ti 5Al 2C 3 materials neutron irradiated at ~400, 630 and 700 °C at a fluence of 2 × 10 25 n m -2 (E > 0.1 MeV) or a displacement dose of ~2 dpa. After irradiation at ~400 °C, anisotropic swelling and loss of 90% flexural strength was observed. After irradiation at ~630–700 °C, properties were unchanged. Microcracking and kinking-delamination had occurred during irradiation at ~630–700 °C. Further examination showed no cavities in Ti 3AlC 2 after irradiation at ~630 °C, and MX and A lamellae were preserved.more » However, disturbance of (0004) reflections corresponding to M-A layers was observed, and the number density of line/planar defects was ~10 23 m -3 of size 5–10 nm. HAADF identified these defects as antisite Ti Al atoms. Finally, Ti 3AlC 2-Ti 5Al 2C 3 shows abrupt dynamic recovery of A-layers from ~630 °C, but a higher temperature appears necessary for full recovery.« less

ISAS' new satellite launcher M-V

NASA Astrophysics Data System (ADS)

Akiba, R.; Matsuo, H.; Kohno, M.

The concept of the M-V, a new version of Japanese satellite launchers that is being developed by the Institute of Space and Astronautical Science, is described. The M-V is a three-stage solid propellant rocket that could lift about 2 tons of payload into LEO. Its first flight is scheduled to be at the beginning of 1995, when M-V will carry an engineering test satelline to prove the technology for Space VLBE. The basic parameters of the M-V launcher, the vehicle configuration diagram, and motor-design diagrams are presented.

New Insulin Glargine 300 U/mL for the Treatment of Type 1 and Type 2 Diabetes Mellitus.

PubMed

Goldman, Jennifer; White, John R

2015-10-01

To describe the studies evaluating the efficacy and safety of new insulin glargine 300 U/mL (Gla-300) as a basal insulin in the treatment of type 1 (T1DM) and type 2 (T2DM) diabetes mellitus. A literature search of MEDLINE was conducted (January 2008-June 2015) using the terms U300, Gla-300, and insulin glargine 300 units/mL and supplemented with congress abstracts published in 2014 and 2015. All English language studies assessing the efficacy and/or safety of Gla-300 were evaluated. The efficacy and safety of once-daily Gla-300 has been compared with insulin glargine 100 U/mL (Gla-100) in the EDITION trials, 6 phase-3, multinational, open-label studies in T1DM and T2DM. Across these studies, Gla-300 consistently demonstrated glycemic control comparable to Gla-100; a mean (standard error) change in glycated hemoglobin A1c of -1.02% (0.03) with both Gla-100 (n = 1235) and Gla-300 (n = 1239) was seen in a patient-level meta-analysis. Gla-300 was associated with comparable or reduced nocturnal hypoglycemia compared with Gla-100; the relative risk for nocturnal hypoglycemia with Gla-300 versus Gla-100 was 0.75 (95% CI = 0.68 to 0.83) in a patient-level meta-analysis. There is also some evidence for less weight gain with Gla-300 compared with Gla-100, despite a higher insulin dose. Gla-300 was well tolerated, with the number of adverse events being comparable to that with Gla-100. These results suggest that Gla-300 may have a place as an alternative, long-acting basal insulin for patients with T1DM or T2DM, with the possibility for improved tolerability. © The Author(s) 2015.

Three-fold increase of M1 strength in 40Ar at 10 MeV excitation energy

NASA Astrophysics Data System (ADS)

Tornow, Werner; Finch, Sean; Krishichayan, Fnu; Tonchev, Anton

2017-09-01

We reexamined the excitation energy region of 40Ar around 9.8 MeV with the goal of determining the known M1 strength located at 9.76 MeV more accurately. The physics motivation was based on the fact that i) the neutrino-nucleus interaction cross section is proportional to the M1 strength of a nucleus, ii) DUNE, the Deep Underground Neutrino Experiment at SURF will be using liquid argon as detector medium, iii) the energy spectrum of supernova neutrinos is peaked at approximately 10 MeV. Mono-energetic and linearly polarized photons of 9.88 MeV were produced via Compton backscattering of 548 nm FEL photons from 543 MeV electrons at the High-Intensity γ-ray Source (HI γS) facility at TUNL. The 1.25 cm diameter photon beam with energy spread of 300 keV (FWHM) interacted with argon gas contained in a high-pressure cell. The cell was viewed with HPGe detectors placed at 90o relative to the incident photon beam in the horizontal and vertical planes to distinguish between E1 and M1 de-excitation γ-rays. Our re-measurement provided an increase in M1 strength by a factor of approximately 3, mostly due to the discovery that the known level in 40Ar at 9.84 MeV is of M1 character and not of E1 character, as previously thought. In addition to the already known M1 state at 9.76 MeV, we observed weaker M1 states at 9.70, 9.81, 9.87, and 9.89 MeV.

Persistent three- and four-atom orbital molecules in the spinel Al V2O4

NASA Astrophysics Data System (ADS)

Browne, Alexander J.; Kimber, Simon A. J.; Attfield, J. Paul

2017-10-01

Electronic instabilities in transition-metal compounds may lead to ground states containing orbital molecules when direct metal-metal orbital interactions occur. The spinel Al V2O4 was reported to contain V717 + orbital heptamers that emerge below a 700 K charge ordering transition. Our x-ray total scattering analysis of Al V2O4 between 300 and 1100 K reveals a very different picture as the postulated heptamers are found to be pairs of spin-singlet V39 + trimers and V48 + tetramers, and these orbital molecules persist to at least 1100 K in a disordered high-temperature cubic phase.

M-V launch vehicle

NASA Astrophysics Data System (ADS)

Matsuo, Hiroki; Kawaguchi, Jun'ichiro

1995-01-01

M-V is the next generation satellite launcher of the Institute of Space and Astronautical Science (IS AS) expected to be a work horse for Japanese scientific missions beyond late 1990s. It is a three staged, solid propellant rocket with 2ton class launch capability into LEO. Its development is underway toward the revised first launch date in 1996. This paper describes the back ground and the design philosophy of M-V along with vehicle characteristics featuring new technology to be introduced. Also given are the development status and the launch schedule.

Calculated and Experimental Vibrational Properties of P700 and the Iron Sulfur Cluster in Photosystem I

NASA Astrophysics Data System (ADS)

Lamichhane, Hari; Hastings, Gary

2009-11-01

Density functional theory (DFT) based vibrational frequency calculations of Fe4S4(SR)4^n- clusters show that the intense iron-sulfur stretching modes lie in the frequency region between 300-400 cm-1. Among them the iron-sulfur ligand (Fe-S^t) stretching modes are more intense and ˜ 30 cm-1 lower in frequency than the iron-sulfur body (Fe-S^b) stretching modes. Calculations in tetrahydrofuran (THF) show that all these iron-sulfur stretching modes of vibration downshift by ˜ 20 cm-1 upon reduction of the molecule. On the other hand, we have not observed any intense bands from chlorophyll a in the frequency region 400 to 320 cm-1 from the calculations. In an attempt to detect modes associated with iron sulfur clusters in PS I we have obtained light induced (P700^+ - P700) FTIR difference spectra for PSI particles from S. 6803 in the far infrared region. We observe difference bands at many frequencies in the 600-300 cm-1 region. Based on our calculations and literature values we claim that the negative bands at 388 cm-1 and 353 cm-1 in the (P700^+ - P700) FTIR difference spectra be assigned to Fe-S^b and Fe-S^t stretching modes of the ground state of the iron-sulfur cluster FB.

Compatibility of an Ultraselective Microcatheter and Epirubicin Loaded 300–500-μm DC Bead in Ex Vivo Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fukuoka, Yasushi, E-mail: miyano.y.fukuoka@gmail.com; Tanaka, Toshihiro, E-mail: toshihir@bf6.so-net.ne.jp; Nishiofuku, Hideyuki, E-mail: nishiofukuhideyuki@yahoo.co.jp

PurposeThe purpose of this study is to examine whether epirubicin loaded DC Bead 300–500 μm in size can pass through a 1.8-Fr ultraselective microcatheter in ex vivo study.MethodsEpirubicin (25 mg/1 mL) loaded 100–300 and 300–500 μm DC Bead were tested. Both sizes were diluted 5, 10, and 30 times using contrast material. Ultraselective microcatheter with the outer diameter of 1.8 Fr and the inner diameter of .017 inch (431.8 μm) was used. The diluted DC Bead was injected at a speed of 1 mL/min, and the pressure was continuously measured. The microspheres’ shapes after ejection were observed by a stereomicroscope.ResultsThe maximum pressure of contrast material alone was 8.40 ± 0.21 psi.more » The maximum pressure in 5, 10, and 30 times dilution groups of 100–300 μm were 9.67 ± 1.18, 9.25 ± 0.25, and 9.71 ± 0.28 psi, respectively, whereas 21.10 ± 10.2, 10.48 ± 2.14, 10.09 ± 0.37 psi, respectively in 300–500 μm groups. The maximum pressure in 5 times dilution group of 300–500 μm was significantly higher than the other groups (P < 0.05). In 300–500 μm, 4 of 10 measurements showed high pressure over 24 psi (the maximum value was 43.5 psi) in 5 times dilution group, whereas in 10 times and 30 times dilution groups, all measurements showed less than 12 psi. No damages of microspheres were found.ConclusionsEpirubicin loaded DC Bead 300–500 μm in size can pass through a 1.8-Fr ultraselective microcatheter. To avoid high resistance due to microspheres’ aggregation, dilution more than 10 times is needed.« less

Arsenic removal by perilla leaf biochar in aqueous solutions and groundwater: An integrated spectroscopic and microscopic examination.

PubMed

Niazi, Nabeel Khan; Bibi, Irshad; Shahid, Muhammad; Ok, Yong Sik; Burton, Edward D; Wang, Hailong; Shaheen, Sabry M; Rinklebe, Jörg; Lüttge, Andreas

2018-01-01

In this study, we examined the removal of arsenite (As(III)) and arsenate (As(V)) by perilla leaf-derived biochars produced at 300 and 700 °C (referred as BC300 and BC700) in aqueous environments. Results revealed that the Langmuir isotherm model provided the best fit for As(III) and As(V) sorption, with the sorption affinity following the order: BC700-As(III) > BC700-As(V) > BC300-As(III) > BC300-As(V) (Q L  = 3.85-11.01 mg g -1 ). In general, As removal decreased (76-60%) with increasing pH from 7 to 10 except for the BC700-As(III) system, where notably higher As removal (88-90%) occurred at pH from 7 to 9. Surface functional moieties contributed to As sequestration by the biochars examined here. However, significantly higher surface area and aromaticity of BC700 favored a greater As removal compared to BC300, suggesting that surface complexation/precipitation dominated As removal by BC700. Arsenic K-edge X-ray absorption near edge structure (XANES) spectroscopy demonstrated that up to 64% of the added As(V) was reduced to As(III) in BC700- and BC300-As(V) sorption experiments, and in As(III) sorption experiments, partial oxidation of As(III) to As(V) occurred (37-39%). However, XANES spectroscopy was limited to precisely quantify As binding with sulfur species as As 2 S 3 -like phase. Both biochars efficiently removed As from natural As-contaminated groundwater (As: 23-190 μg L -1 ; n = 12) despite in the presence of co-occurring anions (e.g., CO 3 2- , PO 4 3- , SO 4 2- ) with the highest levels of As removal observed for BC700 (97-100%). Overall, this study highlights that perilla leaf biochars, notably BC700, possessed the greatest ability to remove As from solution and groundwater (drinking water). Significantly, the integrated spectroscopic techniques advanced our understanding to examine complex redox transformation of As(III)/As(V) with biochar, which are crucial to determine fate of As on biochar in aquatic environments. Copyright �

Insulin glargine 300 U/mL in the management of diabetes: clinical utility and patient perspectives.

PubMed

de Galan, Bastiaan E

2016-01-01

There is ongoing interest in optimizing basal insulin treatment by developing insulins with a flat pharmacological profile, a long duration of action (typically beyond 24 hours) and minimum day-to-day variation. Glargine-300 is a modified form of the long-acting insulin analog glargine in that it has been concentrated at 300 units/mL rather than the conventional 100 units/mL. Glargine-300 has a longer duration of action and a flatter pharmacological profile than original glargine-100. This property allows for more flexibility around the timing of administration, when injected once per day. Open-label studies in patients with diabetes have shown that treatment with glargine-300 achieves comparable glycemic control compared to treatment with glargine-100, albeit with consistently higher insulin requirements. These studies also showed that treatment with glargine-300 was associated with lower risks of nocturnal hypoglycemia in patients with type 2 diabetes, particularly those already on insulin, whereas data are mixed in insulin-naïve patients with type 2 diabetes or in patients with type 1 diabetes. Treatment with glargine-300 did not appear to affect the risk of overall hypoglycemia, whereas studies lacked sufficient power to investigate the effect on the risk of severe hypoglycemia. Future studies need to establish the role of glargine-300 in the treatment of diabetes alongside the other new long-acting insulin analog, insulin degludec, which was recently introduced to the market.

Insulin glargine 300 U/mL in the management of diabetes: clinical utility and patient perspectives

PubMed Central

de Galan, Bastiaan E

2016-01-01

There is ongoing interest in optimizing basal insulin treatment by developing insulins with a flat pharmacological profile, a long duration of action (typically beyond 24 hours) and minimum day-to-day variation. Glargine-300 is a modified form of the long-acting insulin analog glargine in that it has been concentrated at 300 units/mL rather than the conventional 100 units/mL. Glargine-300 has a longer duration of action and a flatter pharmacological profile than original glargine-100. This property allows for more flexibility around the timing of administration, when injected once per day. Open-label studies in patients with diabetes have shown that treatment with glargine-300 achieves comparable glycemic control compared to treatment with glargine-100, albeit with consistently higher insulin requirements. These studies also showed that treatment with glargine-300 was associated with lower risks of nocturnal hypoglycemia in patients with type 2 diabetes, particularly those already on insulin, whereas data are mixed in insulin-naïve patients with type 2 diabetes or in patients with type 1 diabetes. Treatment with glargine-300 did not appear to affect the risk of overall hypoglycemia, whereas studies lacked sufficient power to investigate the effect on the risk of severe hypoglycemia. Future studies need to establish the role of glargine-300 in the treatment of diabetes alongside the other new long-acting insulin analog, insulin degludec, which was recently introduced to the market. PMID:27799746

Analysis of the electrochemistry of hemes with Ems spanning 800 mV

PubMed Central

Zheng, Zhong; Gunner, M. R.

2009-01-01

The free energy of heme reduction in different proteins is found to vary over more than 18 kcal/mol. It is a challenge to determine how proteins manage to achieve this enormous range of Ems with a single type of redox cofactor. Proteins containing 141 unique hemes of a-, b-, and c-type, with bis-His, His-Met, and aquo-His ligation were calculated using Multi-Conformation Continuum Electrostatics (MCCE). The experimental Ems range over 800 mV from −350 mV in cytochrome c3 to 450 mV in cytochrome c peroxidase (vs. SHE). The quantitative analysis of the factors that modulate heme electrochemistry includes the interactions of the heme with its ligands, the solvent, the protein backbone, and sidechains. MCCE calculated Ems are in good agreement with measured values. Using no free parameters the slope of the line comparing calculated and experimental Ems is 0.73 (R2 = 0.90), showing the method accounts for 73% of the observed Em range. Adding a +160 mV correction to the His-Met c-type hemes yields a slope of 0.97 (R2 = 0.93). With the correction 65% of the hemes have an absolute error smaller than 60 mV and 92% are within 120 mV. The overview of heme proteins with known structures and Ems shows both the lowest and highest potential hemes are c-type, whereas the b-type hemes are found in the middle Em range. In solution, bis-His ligation lowers the Em by ≈205 mV relative to hemes with His-Met ligands. The bis-His, aquo-His, and His-Met ligated b-type hemes all cluster about Ems which are ≈200 mV more positive in protein than in water. In contrast, the low potential bis-His c-type hemes are shifted little from in solution, whereas the high potential His-Met c-type hemes are raised by ≈300 mV from solution. The analysis shows that no single type of interaction can be identified as the most important in setting heme electrochemistry in proteins. For example, the loss of solvation (reaction field) energy, which raises the Em, has been suggested to be a major factor in

M-shell x-ray production cross sections for 19 elements in the range Z=54-92 by H/sup +/, He/sup +/ and He/sup + +/ ions from 300 keV to 40 MeV. [Xe, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Yb, Hf, Ta, W, Pt, Au, Hg, Pb, Bi, and U

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mehta, R.; Duggan, J.L.; Kocur, P.M.

1983-04-01

In this report, the measurements done over the last three decades at various laboratories are surveyed. The elements studied were Xe, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Yb, Hf, Ta, W, Pt, Au, Hg, Pb, Bi, and U. The projectile energies investigated range from 300 keV to 40 MeV for the protons and 250 keV to 2.5 MeV for He/sup +/ ions. Also reported are the M-shell x-ray production cross sections of some rare-earth elements recently measured at NTSU. For these measurements the energy of incident /sup 1/H/sup +/ and /sup 4/He/sup +/ ions ranged from 0.25 tomore » 2.5 MeV. The experimental data are compared to the M-shell ionization cross section predictions of first Born approximation, i.e. the PWBA for direct ionization plus the OBK of Nikolaev for electron capture. Comparison is also made with the theory by Brandt and Lapicki that goes beyond the first Born approximation, i.e. the ECPSSR approach which accounts for the Energy loss, Coulomb deflection and Relativistic effects in the Perturbed Stationary State theory.« less

Shared Autonomy Manipulation Data with a Seabotix vLBV300

DOE Data Explorer

Hollinger, Geoffrey; Lawrance, Nicholas

2017-06-19

This report outlines marine field demonstrations for manipulation tasks with a semi-Autonomous Underwater Vehicle (sAUV). The vehicle is built off a Seabotix vLBV300 platform with custom software interfacing it with the Robot Operating System (ROS). The vehicle utilizes an inertial navigation system available from Greensea Systems, Inc. based on a Gladiator Landmark 40 IMU coupled with a Teledyne Explorer Doppler Velocity Log to perform station keeping at a desired location and orientation. We performed two marine trials with the vehicle: a near-shore shared autonomy manipulation trial and an offshore attempted intervention trial. These demonstrations were designed to show the capabilities of our sAUV system for inspection and basic manipulation tasks in real marine environments.

Deposition and characterization of stoichiometric films of V2O5 on Pd(111)

NASA Astrophysics Data System (ADS)

Feng, Xu; Abdel-Rahman, Mohammed K.; Kruppe, Christopher M.; Trenary, Michael

2017-10-01

A simple and efficient method has been used to grow V2O5 thin films on Pd(111) at a substrate temperature of 300 K through physical vapor deposition by heating a fine powder of V2O5 in a non-oxidative, UHV environment. X-ray photoelectron spectroscopy (XPS), reflection absorption infrared spectroscopy (RAIRS) and low energy electron diffraction (LEED) were used to characterize the thin films. When the as-grown films exceed a minimum thickness, characteristic features of V2O5 were revealed by XPS and RAIRS, which confirms the presence of stoichiometric V2O5. LEED indicates no long range order of the as-grown films at 300 K. Annealing to temperatures between 600 and 700 K causes a reduction of V2O5 to VO2 as identified by XPS and the formation of ordered structures as determined by LEED, and VO2 is predominant after annealing to 800 K. After further annealing to 1000 K, only an ordered form of V2O3 is present on Pd(111).

Performance Test Results of the NASA-457M v2 Hall Thruster

NASA Technical Reports Server (NTRS)

Soulas, George C.; Haag, Thomas W.; Herman, Daniel A.; Huang, Wensheng; Kamhawi, Hani; Shastry, Rohit

2012-01-01

Performance testing of a second generation, 50 kW-class Hall thruster labeled NASA-457M v2 was conducted at the NASA Glenn Research Center. This NASA-designed thruster is an excellent candidate for a solar electric propulsion system that supports human exploration missions. Thruster discharge power was varied from 5 to 50 kW over discharge voltage and current ranges of 200 to 500 V and 15 to 100 A, respectively. Anode efficiencies varied from 0.56 to 0.71. The peak efficiency was similar to that of other state-of-the-art high power Hall thrusters, but outperformed these thrusters at lower discharge voltages. The 0.05 to 0.18 higher anode efficiencies of this thruster compared to its predecessor were primarily due to which of two stable discharge modes the thruster was operated. One stable mode was at low magnetic field strengths, which produced high anode efficiencies, and the other at high magnetic fields where its predecessor was operated. Cathode keeper voltages were always within 2.1 to 6.2 V and cathode voltages were within 13 V of tank ground during high anode efficiency operation. However, during operation at high magnetic fields, cathode-to-ground voltage magnitudes increased dramatically, exceeding 30 V, due to the high axial magnetic field strengths in the immediate vicinity of the centrally-mounted cathode. The peak thrust was 2.3 N and this occurred at a total thruster input power of 50.0 kW at a 500 V discharge voltage. The thruster demonstrated a thrust-to-power range of 76.4 mN/kW at low power to 46.1 mN/kW at full power, and a specific impulse range of 1420 to 2740 s. For a discharge voltage of 300 V, where specific impulses would be about 2000 s, thrust efficiencies varied from 0.57 to 0.63.

A continuous dry 300 mK cooler for THz sensing applications.

PubMed

Klemencic, G M; Ade, P A R; Chase, S; Sudiwala, R; Woodcraft, A L

2016-04-01

We describe and demonstrate the automated operation of a novel cryostat design that is capable of maintaining an unloaded base temperature of less than 300 mK continuously, without the need to recycle the gases within the final cold head, as is the case for conventional single shot sorption pumped (3)He cooling systems. This closed dry system uses only 5 l of (3)He gas, making this an economical alternative to traditional systems where a long hold time is required. During testing, a temperature of 365 mK was maintained with a constant 20 μW load, simulating the cooling requirement of a far infrared camera.

Pharmacokinetics and pharmacodynamics of insulin glargine 300 U/mL in the treatment of diabetes and their clinical relevance.

PubMed

Owens, David R

2016-08-01

A more concentrated insulin glargine formulation, containing 300 U/mL (Gla-300) was approved in 2015 in the US and Europe for the treatment of diabetes mellitus in adults. This drug evaluation focuses on the pharmacokinetics (PK) and pharmacodynamics (PD) of Gla-300 from studies published up to May 2016. The clinical relevance of this new formulation will be addressed. Gla-300 was developed to produce a flatter and more prolonged PK/PD profile compared with insulin glargine 100 U/mL (Gla-100) in order to maintain effective glycemic control and reduce the risk of hypoglycemia. Compared to Gla-100, Gla-300 achieves lower and delayed peak concentrations with a PK exposure that is more stable and evenly distributed across a 24-h dosing interval. As a consequence, Gla-300 results in a consistent glucose-lowering effect with less variability over a 24-h dosing interval, which translates to a reduction in the rate of hypoglycemia (particularly nocturnal events).

Microstructural Evolution of AerMet100 Steel Coating on 300M Steel Fabricated by Laser Cladding Technique

NASA Astrophysics Data System (ADS)

Liu, Jian; Li, Jia; Cheng, Xu; Wang, Huaming

2018-02-01

In this paper, the process of coating AerMet100 steel on forged 300M steel with laser cladding was investigated, with a thorough analysis of the chemical composition, microstructure, and hardness of the substrate and the cladding layer as well as the transition zone. Results show that the composition and microhardness of the cladding layer are macroscopically homogenous with the uniformly distributed bainite and a small amount of retained austenite in martensite matrix. The transition zone, which spans approximately 100 μm, yields a gradual change of composition from the cladding layer to 300M steel matrix. The heat-affected zone (HAZ) can be divided into three zones: the sufficiently quenched zone (SQZ), the insufficiently quenched zone (IQZ), and the high tempered zone (HTZ). The SQZ consists of martensitic matrix and bainite, as for the IQZ and the HTZ the microstructures are martensite + tempered martensite and tempered martensite + ferrite, respectively. These complicated microstructures in the HAZ are caused by different peak heating temperatures and heterogeneous microstructures of the as-received 300M steel.

Ion Current Density Study of the NASA-300M and NASA-457Mv2 Hall Thrusters

NASA Technical Reports Server (NTRS)

Huang, Wensheng; Shastry, Rohit; Herman, Daniel A.; Soulas, George C.; Kamhawi, Hani

2012-01-01

NASA Glenn Research Center is developing a Hall thruster in the 15-50 kW range to support future NASA missions. As a part of the process, the performance and plume characteristics of the NASA-300M, a 20-kW Hall thruster, and the NASA-457Mv2, a 50-kW Hall thruster, were evaluated. The collected data will be used to improve the fidelity of the JPL modeling tool, Hall2De, which will then be used to aid the design of the 15-50 kW Hall thruster. This paper gives a detailed overview of the Faraday probe portion of the plume characterization study. The Faraday probe in this study is a near-field probe swept radially at many axial locations downstream of the thruster exit plane. Threshold-based integration limits with threshold values of 1/e, 1/e2, and 1/e3 times the local peak current density are tried for the purpose of ion current integration and divergence angle calculation. The NASA-300M is operated at 7 conditions and the NASA-457Mv2 at 14 conditions. These conditions span discharge voltages of 200 to 500 V and discharge power of 10 to 50 kW. The ion current density profiles of the near-field plume originating from the discharge channel are discovered to strongly resemble Gaussian distributions. A novel analysis approach involving a form of ray tracing is used to determine an effective point of origin for the near-field plume. In the process of performing this analysis, definitive evidence is discovered that showed the near-field plume is bending towards the thruster centerline.

Ion Current Density Study of the NASA-300M and NASA-457Mv2 Hall Thrusters

NASA Technical Reports Server (NTRS)

Huang, Wensheng; Shastry, Rohit; Herman, Daniel A.; Soulas, George C.; Kamhawi, Hani

2012-01-01

NASA Glenn Research Center is developing a Hall thruster in the 15-50 kW range to support future NASA missions. As a part of the process, the performance and plume characteristics of the NASA-300M, a 20-kW Hall thruster, and the NASA-457Mv2, a 50-kW Hall thruster, were evaluated. The collected data will be used to improve the fidelity of the JPL modeling tool, Hall2De, which will then be used to aid the design of the 15-50 kW Hall thruster. This paper gives a detailed overview of the Faraday probe portion of the plume characterization study. The Faraday probe in this study is a near-field probe swept radially at many axial locations downstream of the thruster exit plane. Threshold-based integration limits with threshold values of 1/e, 1/e(sup 2), and 1/e(sup 3) times the local peak current density are tried for the purpose of ion current integration and divergence angle calculation. The NASA-300M is operated at 7 conditions and the NASA-457Mv2 at 14 conditions. These conditions span discharge voltages of 200 to 500 V and discharge power of 10 to 50 kW. The ion current density profiles of the near-field plume originating from the discharge channel are discovered to strongly resemble Gaussian distributions. A novel analysis approach involving a form of ray tracing is used to determine an effective point of origin for the near-field plume. In the process of performing this analysis, definitive evidence is discovered that showed the near-field plume is bending towards the thruster centerline.

A continuous dry 300 mK cooler for THz sensing applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klemencic, G. M., E-mail: Georgina.Klemencic@astro.cf.ac.uk; Ade, P. A. R.; Sudiwala, R.

We describe and demonstrate the automated operation of a novel cryostat design that is capable of maintaining an unloaded base temperature of less than 300 mK continuously, without the need to recycle the gases within the final cold head, as is the case for conventional single shot sorption pumped {sup 3}He cooling systems. This closed dry system uses only 5 l of {sup 3}He gas, making this an economical alternative to traditional systems where a long hold time is required. During testing, a temperature of 365 mK was maintained with a constant 20 μW load, simulating the cooling requirement ofmore » a far infrared camera.« less

Field test of a new instrument to measure UV/Vis (300-700 nm) ambient aerosol extinction spectra in Colorado during DISCOVER-AQ

NASA Astrophysics Data System (ADS)

Jordan, C. E.; Anderson, B. E.; Beyersdorf, A. J.; Dibb, J. E.; Greenslade, M. E.; Martin, R.; Scheuer, E. M.; Shook, M.; Thornhill, K. L., II; Troop, D.; Winstead, E.; Ziemba, L. D.

2014-12-01

An optical instrument has been developed to investigate aerosol extinction spectra in the ambient atmosphere. Based on a White-type cell design and using a differential optical approach, aerosol extinction spectra over the 300-700 nm ultraviolet and visible (UV/Vis) wavelength range are obtained. Laboratory tests conducted at NASA Langley Research Center (NASA LaRC) in March 2014 showed good agreement with Cavity Attenuated Phase Shift (CAPS PMex, Aerodyne Research) extinction measurements (at 450, 530, and 630 nm) for a variety of aerosols, e.g., scatterers such as polystyrene latex spheres and ammonium sulfate; absorbers such as dust (including pigmented minerals), smoke (generated in a miniCAST burning propane) and laboratory smoke analogs (e.g., fullerene soot and aquadag). The instrument was field tested in Colorado in July and August 2014 aboard the NASA mobile laboratory at various ground sites during the DISCOVER-AQ (Deriving Information on Surface Conditions from Column and Vertically Resolved Observations Relevant to Air Quality) field campaign. A description of the instrument, results from the laboratory tests, and summer field data will be presented. The instrument provides a new tool for probing in situ aerosol optical properties that may help inform remote sensing approaches well into the UV range.

Retraction: Using the Medipix3 detector for direct electron imaging in the range 60 keV to 200 keV in electron microscopy Retraction: Using the Medipix3 detector for direct electron imaging in the range 60 keV to 200 keV in electron microscopy

NASA Astrophysics Data System (ADS)

Mir, J. A.; Plackett, R.; Shipsey, I.; dos Santos, J. M. F.

2018-01-01

The paper "Using the Medipix3 detector for direct electron imaging in the range 60keV to 200keV in electron microscopy" by J.A. Mir, R. Plackett, I. Shipsey and J.M.F. dos Santos has been retracted following the authors' request on the basis of the existence of a disagreement about the ownership of the data, to prevent conflict between collaborators.

15 CFR 700.18 - Limitations on placing rated orders.

Code of Federal Regulations, 2012 CFR

2012-01-01

... transportation (Department of Transportation); (v) Water resources (Department of Defense/U.S. Army Corps of... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.18 Limitations on placing...

15 CFR 700.18 - Limitations on placing rated orders.

Code of Federal Regulations, 2014 CFR

2014-01-01

... transportation (Department of Transportation); (v) Water resources (Department of Defense/U.S. Army Corps of... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.18 Limitations on placing...

15 CFR 700.18 - Limitations on placing rated orders.

Code of Federal Regulations, 2013 CFR

2013-01-01

... transportation (Department of Transportation); (v) Water resources (Department of Defense/U.S. Army Corps of... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.18 Limitations on placing...

Farfield Plume Measurement and Analysis on the NASA-300M

NASA Technical Reports Server (NTRS)

Huang, Wensheng; Shastry, Rohit; Soulas, George C.; Kamhawi, Hani

2013-01-01

NASA is developing a 15-kW Hall thruster to support future NASA missions. This activity is funded under the Space Technology Mission Directorate Solar Electric Propulsion Technology Demonstration project. As a part of the development process, the far-field plume characteristics of the NASA-300M, a 20-kW Hall thruster, were studied. The results will be used to study how various aspects of the operation of this thruster affect the overall performance. This data will be used to guide future design work and serve as a baseline for comparison to a magnetically shielded version of the NASA-300M that will be tested in the future. For this study, a far-field Faraday probe was swept in a polar fashion to map the ion current density. An ExB probe (Wien filter), two retarding potential analyzers, and a Langmuir probe were mounted at a fixed location on the thruster axis in the far-field plume. The data reduction method followed recommendations in recent studies by Brown, Reid, and Shastry with modifications that are tailored to the plasma plume environment of high-power Hall thrusters. Results from this and prior testing show that the plume is richer in doubly-charged ions, larger in spatial extent, and capable of greater probe heating than lower power thrusters. These characteristics require special treatment in experimental setup and data analysis, which will be the main focus of this paper. In particular, covered topics will include a new, more accurate, method of integration for analysis of the ExB probe data and effect of secondary electron emission on the Faraday probe data.

Intermediate Nuclear Structure for 2v 2{beta} Decay of {sup 48}Ca Studied by (p, n) and (n, p) Reactions at 300 MeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sakai, H.; Yako, K.

2009-08-26

Angular distributions of the double differential cross sections for the {sup 48}Ca(p,n) and the {sup 48}Ti(n,p) reactions were measured at 300 MeV. A multipole decomposition technique was applied to the spectra to extract the Gamow-Teller (GT) transition strengths. In the (n, p) spectrum beyond 8 MeV excitation energy extra B(GT{sup +}) strengths which are not predicted by the shell model calculation. This extra B(GT{sup +}) strengths significantly contribute to the nuclear matrix element of the 2v2{beta}-decay.

Variability of Coastal and Ocean Water Temperature in the Upper 700 m along the Western Iberian Peninsula from 1975 to 2006

PubMed Central

Santos, Fran; Gómez-Gesteira, Moncho; deCastro, Maite; Álvarez, Inés

2012-01-01

Temperature is observed to have different trends at coastal and ocean locations along the western Iberian Peninsula from 1975 to 2006, which corresponds to the last warming period in the area under study. The analysis was carried out by means of the Simple Ocean Data Assimilation (SODA). Reanalysis data are available at monthly scale with a horizontal resolution of 0.5°×0.5° and a vertical resolution of 40 levels, which allows obtaining information beneath the sea surface. Only the first 21 vertical levels (from 5.0 m to 729.35 m) were considered here, since the most important changes in heat content observed for the world ocean during the last decades, correspond to the upper 700 m. Warming was observed to be considerably higher at ocean locations than at coastal ones. Ocean warming ranged from values on the order of 0.3°C dec−1 near surface to less than 0.1°C dec−1 at 500 m, while coastal warming showed values close to 0.2°C dec−1 near surface, decreasing rapidly below 0.1°C dec−1 for depths on the order of 50 m. The heat content anomaly for the upper 700 m, showed a sharp increase from coast (0.46 Wm−2) to ocean (1.59 Wm−2). The difference between coastal and ocean values was related to the presence of coastal upwelling, which partially inhibits the warming from surface of near shore water. PMID:23226533

[99mTc(V)-DMSA accumulation in gynecomastia].

PubMed

Ohta, H

1998-11-01

The accumulation of 99mTc(V)-DMSA in bilateral breasts was recognized in a 60-year-old male with drug-induced gynecomastia. There are some reports describing 99mTc(V)-DMSA accumulation in normal female breast, fibrous dysplasia of the breast and metastatic lesions of breast carcinoma, but to my knowledge, there have been no reports describing 99mTc(V)-DMSA accumulation in gynecomastia.

An analytical X-ray CdTe detector response matrix for incomplete charge collection correction for photon energies up to 300 keV

NASA Astrophysics Data System (ADS)

Kurková, Dana; Judas, Libor

2018-05-01

Gamma and X-ray energy spectra measured with semiconductor detectors suffer from various distortions, one of them being so-called "tailing" caused by an incomplete charge collection. Using the Hecht equation, a response matrix of size 321 × 321 was constructed which was used to correct the effect of incomplete charge collection. The correction matrix was constructed analytically for an arbitrary energy bin and the size of the energy bin thus defines the width of the spectral window. The correction matrix can be applied separately from other possible spectral corrections or it can be incorporated into an already existing response matrix of the detector. The correction was tested and its adjustable parameters were optimized on the line spectra of 57Co measured with a cadmium telluride (CdTe) detector in a spectral range from 0 up to 160 keV. The best results were obtained when the values of the free path of holes were spread over a range from 0.4 to 1.0 cm and weighted by a Gauss function. The model with the optimized parameter values was then used to correct the line spectra of 152Eu in a spectral range from 0 up to 530 keV. An improvement in the energy resolution at full width at half maximum from 2.40 % ± 0.28 % to 0.96 % ± 0.28 % was achieved at 344.27 keV. Spectra of "narrow spectrum series" beams, N120, N150, N200, N250 and N300, generated with tube voltages of 120 kV, 150 kV, 200 kV, 250 kV and 300 kV respectively, and measured with the CdTe detector, were corrected in the spectral range from 0 to 160 keV (N120 and N150) and from 0 to 530 keV (N200, N250, N300). All the measured spectra correspond both qualitatively and quantitatively to the available reference data after the correction. To obtain better correspondence between N150, N200, N250 and N300 spectra and the reference data, lower values of the free paths of holes (range from 0.16 to 0.65 cm) were used for X-ray spectra correction, which suggests energy dependence of the phenomenon.

Design of a self-aligned, wide temperature range (300 mK-300 K) atomic force microscope/magnetic force microscope with 10 nm magnetic force microscope resolution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karcı, Özgür; Department of Nanotechnology and Nanomedicine, Hacettepe University, Beytepe, 06800 Ankara; Dede, Münir

We describe the design of a wide temperature range (300 mK-300 K) atomic force microscope/magnetic force microscope with a self-aligned fibre-cantilever mechanism. An alignment chip with alignment groves and a special mechanical design are used to eliminate tedious and time consuming fibre-cantilever alignment procedure for the entire temperature range. A low noise, Michelson fibre interferometer was integrated into the system for measuring deflection of the cantilever. The spectral noise density of the system was measured to be ~12 fm/√Hz at 4.2 K at 3 mW incident optical power. Abrikosov vortices in BSCCO(2212) single crystal sample and a high density hardmore » disk sample were imaged at 10 nm resolution to demonstrate the performance of the system.« less

COSMIC RADIATION AND TUBERCULOSIS. V. INFLUENCE OF COSMIC RADIATION ON TUBERCULOSIS AT HIGH ALTITUDE (2,300m) AND AT SEA-LEVEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ong, S.G.

1964-02-01

Tuberculous mice exposed to cosmic radiation at 2,300 m showed a significantly greater mean survival time and a significantly greater number of survivors than tuberculous mice exposed to cosmic radiation at sea-level. At high altitude as well as at sea-level the female showed a significantly greater mean survival than the male. The mean survival time of the male or female at high altitude is significantly greater than that of the male or female at sealevel. At high altitude there is no significant difference in montality between male and female. At sea-level the female showed a significantly greater number of survivorsmore » than the male. The pooled data showed a significantly greater number of survivors of the female. At high altitude as well as at sea- level the lung lesions diminished, whereas the spleen lesions increased significantly with increasing survival time. (auth)« less

Investigation of sodium arsenite, thioacetamide, and diethanolamine in the alkaline comet assay: Part of the JaCVAM comet validation exercise.

PubMed

Beevers, Carol; Henderson, Debbie; Lillford, Lucinda

2015-07-01

As part of the Japanese Center for the Validation of Alternative Methods (JaCVAM)-initiative international validation study of the in vivo rat alkaline comet assay (comet assay), we examined sodium arsenite, thioacetamide, and diethanolamine. Using the JaCVAM approved study protocol version 14.2, each chemical was tested in male rats up to maximum tolerated dose levels and DNA damage in the liver and stomach was assessed approximately 3h after the final administration by gavage. Histopathology assessments of liver and stomach sections from the same animals were also examined for evidence of cytotoxicity or necrosis. No evidence of DNA damage was observed in the stomach of animals treated with sodium arsenite at 7.5, 15, or 30 mg/kg/day. However, equivocal findings were found in the liver, where increases in DNA migration were observed in two independent experiments, but not in all treated animals and not at the same dose levels. Thioacetamide caused an increase in DNA migration in the stomach of rats treated at 19, 38, and 75 mg/kg/day, but not in the liver, despite evidence of marked hepatotoxicity following histopathology assessments. No evidence of DNA damage was observed in the stomach or liver of animals treated with diethanolamine at 175, 350, or 700 mg/kg/day. Copyright © 2015 Elsevier B.V. All rights reserved.

Attainment of 40.5 pm spatial resolution using 300 kV scanning transmission electron microscope equipped with fifth-order aberration corrector.

PubMed

Morishita, Shigeyuki; Ishikawa, Ryo; Kohno, Yuji; Sawada, Hidetaka; Shibata, Naoya; Ikuhara, Yuichi

2018-02-01

The achievement of a fine electron probe for high-resolution imaging in scanning transmission electron microscopy requires technological developments, especially in electron optics. For this purpose, we developed a microscope with a fifth-order aberration corrector that operates at 300 kV. The contrast flat region in an experimental Ronchigram, which indicates the aberration-free angle, was expanded to 70 mrad. By using a probe with convergence angle of 40 mrad in the scanning transmission electron microscope at 300 kV, we attained the spatial resolution of 40.5 pm, which is the projected interatomic distance between Ga-Ga atomic columns of GaN observed along [212] direction.

High temperature tensile properties of V-4Cr-4Ti

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zinkle, S.J.; Rowcliffe, A.F.; Stevens, C.O.

Tensile tests have been performed on V-4Cr-4Ti at 750 and 800 C in order to extend the data base beyond the current limit of 700 C. From comparison with previous measurements, the yield strength is nearly constant and tensile elongations decrease slightly with increasing temperature between 300 and 800 C. The ultimate strength exhibits an apparent maximum near 600 C (attributable to dynamic strain aging) but adequate strength is maintained up to 800 C. The reduction in area measured on tensile specimens remained high ({approximately}80%) for test temperatures up to 800 C, in contrast to previous reported results.

48 CFR 717.700 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false General. 717.700 Section 717.700 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Pharmaceutical Products 717.700 General. Section...

48 CFR 717.700 - General.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false General. 717.700 Section 717.700 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Pharmaceutical Products 717.700 General. Section...

Use of the rVV10 Nonlocal Correlation Functional in the B97M-V Density Functional: Defining B97M-rV and Related Functionals [On the Use of the rVV10 Nonlocal Correlation Functional in the B97M-V Density Functional: Defining B97M-rV and Related Functionals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mardirossian, Narbe; Ruiz Pestana, Luis; Womack, James C.

The VV10 and rVV10 nonlocal correlation functionals are consistently implemented and assessed, with the goal of determining if the rVV10 nonlocal correlation functional can replace the VV10 nonlocal correlation functional in the recently developed B97M-V density functional, to give the B97M-rV density functional. Along the way, four density functionals are simultaneously tested: VV10, rVV10, B97M-V, and B97M-rV. An initial assessment is carried out across the S22 data set, and the short-range damping variable, b, is varied for all four density functionals in order to determine the sensitivity of the functionals to the empirical parameter. The results of this test indicatemore » that a value of b = 6 (fortuitously the same as that in B97M-V) is suitable for B97M-rV. The functionals are then compared across an extensive database of interaction energies, and it is demonstrated that B97M-rV either matches or outperforms B97M-V for all of the tests considered. Finally, the optimization of b across the S22 data set is extended to two range-separated hybrid density functionals, ωB97X-V and ωB97M-V, and a value of b = 6.2 is recommended for both ωB97X-rV and ωB97M-rV.« less

Use of the rVV10 Nonlocal Correlation Functional in the B97M-V Density Functional: Defining B97M-rV and Related Functionals [On the Use of the rVV10 Nonlocal Correlation Functional in the B97M-V Density Functional: Defining B97M-rV and Related Functionals

DOE PAGES

Mardirossian, Narbe; Ruiz Pestana, Luis; Womack, James C.; ...

2016-12-06

The VV10 and rVV10 nonlocal correlation functionals are consistently implemented and assessed, with the goal of determining if the rVV10 nonlocal correlation functional can replace the VV10 nonlocal correlation functional in the recently developed B97M-V density functional, to give the B97M-rV density functional. Along the way, four density functionals are simultaneously tested: VV10, rVV10, B97M-V, and B97M-rV. An initial assessment is carried out across the S22 data set, and the short-range damping variable, b, is varied for all four density functionals in order to determine the sensitivity of the functionals to the empirical parameter. The results of this test indicatemore » that a value of b = 6 (fortuitously the same as that in B97M-V) is suitable for B97M-rV. The functionals are then compared across an extensive database of interaction energies, and it is demonstrated that B97M-rV either matches or outperforms B97M-V for all of the tests considered. Finally, the optimization of b across the S22 data set is extended to two range-separated hybrid density functionals, ωB97X-V and ωB97M-V, and a value of b = 6.2 is recommended for both ωB97X-rV and ωB97M-rV.« less

A 300-million-year record of atmospheric carbon dioxide from fossil plant cuticles

NASA Astrophysics Data System (ADS)

Retallack, Gregory J.

2001-05-01

To understand better the link between atmospheric CO2 concentrations and climate over geological time, records of past CO2 are reconstructed from geochemical proxies. Although these records have provided us with a broad picture of CO2 variation throughout the Phanerozoic eon (the past 544Myr), inconsistencies and gaps remain that still need to be resolved. Here I present a continuous 300-Myr record of stomatal abundance from fossil leaves of four genera of plants that are closely related to the present-day Ginkgo tree. Using the known relationship between leaf stomatal abundance and growing season CO2 concentrations, I reconstruct past atmospheric CO2 concentrations. For the past 300Myr, only two intervals of low CO2 (<1,000p.p.m.v.) are inferred, both of which coincide with known ice ages in Neogene (1-8Myr) and early Permian (275-290Myr) times. But for most of the Mesozoic era (65-250Myr), CO2 levels were high (1,000-2,000p.p.m.v.), with transient excursions to even higher CO2 (>2,000p.p.m.v.) concentrations. These results are consistent with some reconstructions of past CO2 (refs 1, 2) and palaeotemperature records, but suggest that CO2 reconstructions based on carbon isotope proxies may be compromised by episodic outbursts of isotopically light methane. These results support the role of water vapour, methane and CO2 in greenhouse climate warming over the past 300Myr.

15 CFR 700.93 - Communications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Communications. 700.93 Section 700.93 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF... PRIORITIES AND ALLOCATIONS SYSTEM Miscellaneous Provisions § 700.93 Communications. All communications...

15 CFR 700.93 - Communications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Communications. 700.93 Section 700.93 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF... PRIORITIES AND ALLOCATIONS SYSTEM Miscellaneous Provisions § 700.93 Communications. All communications...

32 CFR 700.819 - Records.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Records. 700.819 Section 700.819 National... OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.819 Records. The commanding officer shall require that records relative to...

32 CFR 700.819 - Records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Records. 700.819 Section 700.819 National... OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.819 Records. The commanding officer shall require that records relative to...

32 CFR 700.819 - Records.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Records. 700.819 Section 700.819 National... OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.819 Records. The commanding officer shall require that records relative to...

32 CFR 700.819 - Records.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Records. 700.819 Section 700.819 National... OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.819 Records. The commanding officer shall require that records relative to...

32 CFR 700.819 - Records.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Records. 700.819 Section 700.819 National... OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.819 Records. The commanding officer shall require that records relative to...

25 CFR 700.503 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Definitions. 700.503 Section 700.503 Indians THE OFFICE... Responsibility and Conduct § 700.503 Definitions. (a) Special Government Employee: An officer or employee who has.... (d) Persons: An individual, corporation, company, association, firm, partnership, society, joint...

Microdosimetry measurements characterizing the radiation fields of 300 MeV/u 12C and 185 MeV/u 7Li pencil beams stopping in water

NASA Astrophysics Data System (ADS)

Martino, G.; Durante, M.; Schardt, D.

2010-06-01

In order to characterize the complex radiation field produced by heavy-ion beams in water, in particular the lateral dose fall-off and the radiation quality, microdosimetry measurements were performed at GSI Darmstadt using pencil-like beams of 300 MeV/u 12C and 185 MeV/u 7Li ions delivered by the heavy-ion synchrotron SIS-18. The ion beams (range in water about 17 cm) were stopped in the center of a 30 × 30 × 30 cm3 water phantom and their radiation field was investigated by in-phantom measurements using a tissue-equivalent proportional chamber (TEPC). The chamber was placed at 35 different positions in the central plane at various depths along the beam axis and at radial distances of 0, 1, 2, 5 and 10 cm. The off-axis measurements for both 12C and 7Li ions show very similar distributions of the lineal energy, all peaking between 1 and 10 \\rm keV\\,\\mu m^{-1} which is a typical range covered by secondary hydrogen fragments and neutrons. The radiation quality given by the dose-mean lineal energy \\overline{y}_D was found to be at a constant level of 1-2 \\rm keV\\,\\mu m^{-1} at radial distances larger than 2 cm. The relative absorbed dose at each position was obtained by integration of the measured spectra normalized to the number of incident primary beam particles. The results confirm that the lateral dose profile of heavy ions shows an extremely steep fall-off, with relative values of about 10-3, 10-4 and 10-5 at the 2, 5 and 10 cm distance from the beam axis, respectively. The depth-dose curves at a fixed distance from the beam axis slowly rise until they reach the depth of the Bragg peak, reflecting the build-up of secondary fragments with increasing penetration depth. The measured 12C dose profiles were found to be in good agreement with a similar experimental study at HIMAC (Japan).

15 CFR 700.2 - Introduction.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Introduction. 700.2 Section 700.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF... PRIORITIES AND ALLOCATIONS SYSTEM Overview § 700.2 Introduction. (a) Certain national defense and energy...

25 CFR 700.543 - Gambling.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Gambling. 700.543 Section 700.543 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.543 Gambling. An employee shall not sponsor or participate in any gambling activity...

25 CFR 700.45 - Business.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Business. 700.45 Section 700.45 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.45 Business. The term business means any lawful activity, except a nonprofit...

25 CFR 700.45 - Business.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Business. 700.45 Section 700.45 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.45 Business. The term business means any lawful activity, except a nonprofit...

25 CFR 700.45 - Business.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Business. 700.45 Section 700.45 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.45 Business. The term business means any lawful activity, except a nonprofit...

25 CFR 700.45 - Business.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Business. 700.45 Section 700.45 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.45 Business. The term business means any lawful activity, except a nonprofit...

25 CFR 700.77 - Livestock.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Livestock. 700.77 Section 700.77 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.77 Livestock. The term livestock shall mean all domesticated animals of every...

25 CFR 700.543 - Gambling.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Gambling. 700.543 Section 700.543 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.543 Gambling. An employee shall not sponsor or participate in any gambling activity...

25 CFR 700.543 - Gambling.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Gambling. 700.543 Section 700.543 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.543 Gambling. An employee shall not sponsor or participate in any gambling activity...

25 CFR 700.543 - Gambling.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Gambling. 700.543 Section 700.543 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.543 Gambling. An employee shall not sponsor or participate in any gambling activity...

25 CFR 700.543 - Gambling.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Gambling. 700.543 Section 700.543 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.543 Gambling. An employee shall not sponsor or participate in any gambling activity...

25 CFR 700.45 - Business.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Business. 700.45 Section 700.45 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.45 Business. The term business means any lawful activity, except a nonprofit...

25 CFR 700.475 - Reports.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Reports. 700.475 Section 700.475 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.475 Reports. Reports shall be furnished by any recipient of financial assistance under this...

25 CFR 700.505 - Coverage.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Coverage. 700.505 Section 700.505 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.505 Coverage. The regulations contained in this part apply to all Commission...

25 CFR 700.505 - Coverage.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Coverage. 700.505 Section 700.505 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.505 Coverage. The regulations contained in this part apply to all Commission...

25 CFR 700.505 - Coverage.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Coverage. 700.505 Section 700.505 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.505 Coverage. The regulations contained in this part apply to all Commission...

25 CFR 700.505 - Coverage.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Coverage. 700.505 Section 700.505 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.505 Coverage. The regulations contained in this part apply to all Commission...

25 CFR 700.505 - Coverage.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Coverage. 700.505 Section 700.505 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.505 Coverage. The regulations contained in this part apply to all Commission...

31 CFR 700.14 - Smoking.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Smoking. 700.14 Section 700.14 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT... ENFORCEMENT TRAINING CENTER (FLETC) BUILDINGS AND GROUNDS § 700.14 Smoking. Smoking of cigarettes, cigars and...

31 CFR 700.14 - Smoking.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Smoking. 700.14 Section 700.14 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT... ENFORCEMENT TRAINING CENTER (FLETC) BUILDINGS AND GROUNDS § 700.14 Smoking. Smoking of cigarettes, cigars and...

31 CFR 700.14 - Smoking.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Smoking. 700.14 Section 700.14 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT... ENFORCEMENT TRAINING CENTER (FLETC) BUILDINGS AND GROUNDS § 700.14 Smoking. Smoking of cigarettes, cigars and...

31 CFR 700.14 - Smoking.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Smoking. 700.14 Section 700.14 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT... ENFORCEMENT TRAINING CENTER (FLETC) BUILDINGS AND GROUNDS § 700.14 Smoking. Smoking of cigarettes, cigars and...

31 CFR 700.14 - Smoking.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Smoking. 700.14 Section 700.14 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT... ENFORCEMENT TRAINING CENTER (FLETC) BUILDINGS AND GROUNDS § 700.14 Smoking. Smoking of cigarettes, cigars and...

15 CFR 700.7 - Compliance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Compliance. 700.7 Section 700.7 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF... PRIORITIES AND ALLOCATIONS SYSTEM Overview § 700.7 Compliance. (a) Compliance with the provisions of this...

15 CFR 700.7 - Compliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Compliance. 700.7 Section 700.7 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF... PRIORITIES AND ALLOCATIONS SYSTEM Overview § 700.7 Compliance. (a) Compliance with the provisions of this...

Effects of MeJA on Arabidopsis metabolome under endogenous JA deficiency

NASA Astrophysics Data System (ADS)

Cao, Jingjing; Li, Mengya; Chen, Jian; Liu, Pei; Li, Zhen

2016-11-01

Jasmonates (JAs) play important roles in plant growth, development and defense. Comprehensive metabolomics profiling of plants under JA treatment provides insights into the interaction and regulation network of plant hormones. Here we applied high resolution mass spectrometry based metabolomics approach on Arabidopsis wild type and JA synthesis deficiency mutant opr3. The effects of exogenous MeJA treatment on the metabolites of opr3 were investigated. More than 10000 ion signals were detected and more than 2000 signals showed significant variation in different genotypes and treatment groups. Multivariate statistic analyses (PCA and PLS-DA) were performed and a differential compound library containing 174 metabolites with high resolution precursor ion-product ions pairs was obtained. Classification and pathway analysis of 109 identified compounds in this library showed that glucosinolates and tryptophan metabolism, amino acids and small peptides metabolism, lipid metabolism, especially fatty acyls metabolism, were impacted by endogenous JA deficiency and exogenous MeJA treatment. These results were further verified by quantitative reverse transcription PCR (RT-qPCR) analysis of 21 related genes involved in the metabolism of glucosinolates, tryptophan and α-linolenic acid pathways. The results would greatly enhance our understanding of the biological functions of JA.

The Status and Promise of Advanced M&V: An Overview of “M&V 2.0” Methods, Tools, and Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Franconi, Ellen; Gee, Matt; Goldberg, Miriam

Advanced measurement and verification (M&V) of energy efficiency savings, often referred to as M&V 2.0 or advanced M&V, is currently an object of much industry attention. Thus far, however, there has been a lack of clarity about what techniques M&V 2.0 includes, how those techniques differ from traditional approaches, what the key considerations are for their use, and what value propositions M&V 2.0 presents to different stakeholders. The objective of this paper is to provide background information and frame key discussion points related to advanced M&V. The paper identifies the benefits, methods, and requirements of advanced M&V and outlines keymore » technical issues for applying these methods. It presents an overview of the distinguishing elements of M&V 2.0 tools and of how the industry is addressing needs for tool testing, consistency, and standardization, and it identifies opportunities for collaboration. In this paper, we consider two key features of M&V 2.0: (1) automated analytics that can provide ongoing, near-real-time savings estimates, and (2) increased data granularity in terms of frequency, volume, or end-use detail. Greater data granularity for large numbers of customers, such as that derived from comprehensive implementation of advanced metering infrastructure (AMI) systems, leads to very large data volumes. This drives interest in automated processing systems. It is worth noting, however, that automated processing can provide value even when applied to less granular data, such as monthly consumption data series. Likewise, more granular data, such as interval or end-use data, delivers value with or without automated processing, provided the processing is manageable. But it is the combination of greater data detail with automated processing that offers the greatest opportunity for value. Using M&V methods that capture load shapes together with automated processing1 can determine savings in near-real time to provide stakeholders with more timely

32 CFR 700.303 - Succession.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Succession. 700.303 Section 700.303 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... Secretary of the Navy § 700.303 Succession. If the Secretary of the Navy dies, resigns, is removed from...

32 CFR 700.303 - Succession.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Succession. 700.303 Section 700.303 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... Secretary of the Navy § 700.303 Succession. If the Secretary of the Navy dies, resigns, is removed from...

32 CFR 700.303 - Succession.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Succession. 700.303 Section 700.303 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... Secretary of the Navy § 700.303 Succession. If the Secretary of the Navy dies, resigns, is removed from...

32 CFR 700.303 - Succession.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Succession. 700.303 Section 700.303 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... Secretary of the Navy § 700.303 Succession. If the Secretary of the Navy dies, resigns, is removed from...

32 CFR 700.303 - Succession.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Succession. 700.303 Section 700.303 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... Secretary of the Navy § 700.303 Succession. If the Secretary of the Navy dies, resigns, is removed from...

25 CFR 700.839 - Report.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Report. 700.839 Section 700.839 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.839 Report. Each Federal Land Manager, when requested by the Secretary of the Interior, shall submit...

25 CFR 700.839 - Report.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Report. 700.839 Section 700.839 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.839 Report. Each Federal Land Manager, when requested by the Secretary of the Interior, shall submit...

25 CFR 700.839 - Report.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Report. 700.839 Section 700.839 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.839 Report. Each Federal Land Manager, when requested by the Secretary of the Interior, shall submit...

25 CFR 700.803 - Authority.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Authority. 700.803 Section 700.803 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.803 Authority. The regulations in this part are promulgated pursuant to section 10(b) of the...

25 CFR 700.839 - Report.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Report. 700.839 Section 700.839 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.839 Report. Each Federal Land Manager, when requested by the Secretary of the Interior, shall submit...

7 CFR 51.700 - Discoloration.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Discoloration. 51.700 Section 51.700 Agriculture..., California, and Arizona) Definitions § 51.700 Discoloration. Discoloration means russeting of light shade of... fairly smooth, superficial scars or other means may be allowed on a greater area, or darker shades may be...

7 CFR 51.700 - Discoloration.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Discoloration. 51.700 Section 51.700 Agriculture..., California, and Arizona) Definitions § 51.700 Discoloration. Discoloration means russeting of light shade of... fairly smooth, superficial scars or other means may be allowed on a greater area, or darker shades may be...

30 CFR 700.10 - Information collection.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Information collection. 700.10 Section 700.10... GENERAL § 700.10 Information collection. The collection of information, and recordkeeping requirements... under 44 U.S.C. 3501 et seq. and assigned clearance number 1029-0094. The information collected in § 700...

30 CFR 700.10 - Information collection.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Information collection. 700.10 Section 700.10... GENERAL § 700.10 Information collection. The collection of information, and recordkeeping requirements... under 44 U.S.C. 3501 et seq. and assigned clearance number 1029-0094. The information collected in § 700...

Mechanical Properties of Aerojet, Thiokol, and JA2 High-Energy Gun Propellants at 1.5 m/s Deformation Rate

DTIC Science & Technology

2002-01-01

a2 6 n -32 4C La /C A> i c 4S Figure 5. Remains of specimens tested at 210, 630, and -32 0C. 5 I AUg 2001 "-1t AERQJET/"THIDKOL LOTS 0111W PM 4-40.00...10.00 +78.00 STRESS (Mra) -THIOKOL LOT LA -10T3--01 +5.C THIOKOL LOT JA-IEZ35--Z-02 JAZ LOT HCL03JO14-001 -28.00 AE J>:T? +0.00 4.00 0.0 .0 *20.0 O30 +40M0...WARREN MI 48397-5000 MATERIAL SCIENCE TEAM AMSSB RSS 14 BENET LABORATORIES J HERBERT AMSTA AR CCB M SENNETT R FISCELLA KANSAS ST M SOJA NATICK MA 01760

Substantial enhancement in intrinsic coercivity on M-type strontium hexaferrite through the increase in magneto-crystalline anisotropy by co-doping of group-V and alkali elements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahn, Kyunghan, E-mail: kyunghan.ahn@samsung.com; Ryu, Byungki; Korolev, Dmitry

2013-12-09

The effect of d{sup 1} impurity doping in Sr-hexaferrite (SrM) on the magnetic anisotropy is investigated. First-principles calculations revealed that group-V elements (V, Nb) are stabilized with co-doping of alkali elements. Na{sup 1+}/K{sup 1+} doping at Sr{sup 2+}-site is found to be critical to form the d{sup 1} impurities at Fe-site. Experimentally, Na–V doped SrM shows the intrinsic coercivity of ∼5.4 kOe, which is ∼300% enhancement compared to undoped SrM and comparable value to La–Co co-doped SrM. Finally, the spin-orbit coupling from non-vanishing angular momentum of d{sup 1} impurity in SrM should be a main factor for such a substantialmore » improvement of intrinsic coercivity.« less

Insulin glargine 300 U/mL for basal insulin therapy in type 1 and type 2 diabetes mellitus.

PubMed

Lau, Ip Tim; Lee, Ka Fai; So, Wing Yee; Tan, Kathryn; Yeung, Vincent Tok Fai

2017-01-01

To review published clinical studies on the efficacy and safety of new insulin glargine 300 units/mL (Gla-300), a new long-acting insulin analog, for the treatment of type 1 and type 2 diabetes mellitus (T1DM, T2DM). Data sources comprised primary research articles on Gla-300, including pharmacodynamic, pharmacokinetic, and clinical studies. In pharmacodynamic and pharmacokinetic studies, Gla-300 showed a flatter time-action profile and longer duration of action than Gla-100. Noninferiority of Gla-300 versus Gla-100 for lowering of glycated hemoglobin was demonstrated in Phase III clinical studies covering a range of T1DM and T2DM patient populations. Over 6-12 months of follow-up, Gla-300 consistently showed comparable glycemic efficacy with less hypoglycemia vs Gla-100, even during the first 8 weeks of treatment. Although titrated insulin doses were 11%-17% higher with Gla-300 vs Gla-100, changes in body weight were similar or favored Gla-300. Clinical studies provide evidence that the pharmacodynamic and pharmacokinetic properties of Gla-300 may translate into clinical benefits in both T1DM and T2DM. Gla-300 may provide a new option for people initiating basal insulin, those requiring higher basal insulin doses, those with T1DM, and those who may be at increased risk for hypoglycemia, such as people with chronic kidney disease, the elderly, and those with cardiovascular comorbidities.

Insulin glargine 300 U/mL for basal insulin therapy in type 1 and type 2 diabetes mellitus

PubMed Central

Lau, Ip Tim; Lee, Ka Fai; So, Wing Yee; Tan, Kathryn; Yeung, Vincent Tok Fai

2017-01-01

Objective To review published clinical studies on the efficacy and safety of new insulin glargine 300 units/mL (Gla-300), a new long-acting insulin analog, for the treatment of type 1 and type 2 diabetes mellitus (T1DM, T2DM) Materials and methods Data sources comprised primary research articles on Gla-300, including pharmacodynamic, pharmacokinetic, and clinical studies. Results In pharmacodynamic and pharmacokinetic studies, Gla-300 showed a flatter time–action profile and longer duration of action than Gla-100. Noninferiority of Gla-300 versus Gla-100 for lowering of glycated hemoglobin was demonstrated in Phase III clinical studies covering a range of T1DM and T2DM patient populations. Over 6–12 months of follow-up, Gla-300 consistently showed comparable glycemic efficacy with less hypoglycemia vs Gla-100, even during the first 8 weeks of treatment. Although titrated insulin doses were 11%–17% higher with Gla-300 vs Gla-100, changes in body weight were similar or favored Gla-300. Conclusion Clinical studies provide evidence that the pharmacodynamic and pharmacokinetic properties of Gla-300 may translate into clinical benefits in both T1DM and T2DM. Gla-300 may provide a new option for people initiating basal insulin, those requiring higher basal insulin doses, those with T1DM, and those who may be at increased risk for hypoglycemia, such as people with chronic kidney disease, the elderly, and those with cardiovascular comorbidities. PMID:28721081

32 CFR 700.502 - Succession.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Succession. 700.502 Section 700.502 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... § 700.502 Succession. When there is a vacancy in the office of Commandant of the Marine Corps, or during...

32 CFR 700.502 - Succession.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Succession. 700.502 Section 700.502 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... § 700.502 Succession. When there is a vacancy in the office of Commandant of the Marine Corps, or during...

32 CFR 700.502 - Succession.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Succession. 700.502 Section 700.502 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... § 700.502 Succession. When there is a vacancy in the office of Commandant of the Marine Corps, or during...

32 CFR 700.502 - Succession.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Succession. 700.502 Section 700.502 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... § 700.502 Succession. When there is a vacancy in the office of Commandant of the Marine Corps, or during...

32 CFR 700.502 - Succession.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Succession. 700.502 Section 700.502 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... § 700.502 Succession. When there is a vacancy in the office of Commandant of the Marine Corps, or during...

25 CFR 700.703 - Authority.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Authority. 700.703 Section 700.703 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.703 Authority. It is within the authority of the Commissioner on Navajo and Hopi Indian Relocation to...

Single and double delta production in the 3He(γ,π+π-) reaction at 380<=Eγ<=700 MeV

NASA Astrophysics Data System (ADS)

Watts, D. G.; Huber, G. M.; Lolos, G. J.; Lasiuk, B.; Kato, S.; Koike, M.; Maruyama, K.; Niki, K.; Wada, Y.; Maeda, K.; Suda, T.; Emura, T.; Miyamoto, H.; Endo, S.; Sumi, Y.; Konno, O.; Yamazaki, H.; Itoh, H.; Maki, T.; Sasaki, A.

1997-04-01

Results are presented for the 3He(γ,π+π-) reaction in the region 380 <=Eγ<=700 MeV, investigated with the use of a 10% duty factor tagged photon beam, in conjunction with the TAGX multiparticle spectrometer. The study of such multipion photoproduction reactions has motivated a number of chiral symmetric models, and is expected to provide an insight on the role of the Δ and N* resonances in the nuclear medium. From comparisons of the data with simple reaction simulations, it was found that the data were best fit with a combination of multibody phase space channels, quasifree Δ and N*, and ΔΔ production channels. The results are compared with other double pion photoproduction reactions on hydrogen and deuterium.

Modeling and simulation of Charpy impact test of maraging steel 300 using Abaqus

NASA Astrophysics Data System (ADS)

Madhusudhan, D.; Chand, Suresh; Ganesh, S.; Saibhargavi, U.

2018-03-01

This work emphasizes the modeling and simulation of Charpy impact test to evaluate fracture energy at different pendulum velocities of armor maraging steel 300 using ABAQUS. To evaluate the fracture energy, V-notch specimen is fractured using the Johnson and Cook Damage model. The Charpy impact tests are of great importance related to fracture properties of steels. The objective of this work is to present absorbed energy variation at pendulum velocities of 5 m/sec, 6 m/sec, 7 m/sec and 9 m/sec in addition to stress distribution at v-notch. Finite Element Method of modeling for three dimensional specimens is used for simulation in commercial software of ABAQUS.

The Development of III-V Semiconductor MOSFETs for Future CMOS Applications

NASA Astrophysics Data System (ADS)

Greene, Andrew M.

Alternative channel materials with superior transport properties over conventional strained silicon are required for supply voltage scaling in low power complementary metal-oxide-semiconductor (CMOS) integrated circuits. Group III-V compound semiconductor systems offer a potential solution due to their high carrier mobility, low carrier effective mass and large injection velocity. The enhancement in transistor drive current at a lower overdrive voltage allows for the scaling of supply voltage while maintaining high switching performance. This thesis focuses on overcoming several material and processing challenges associated with III-V semiconductor development including a low thermal processing budget, high interface trap state density (Dit), low resistance source/drain contacts and growth on lattice mismatched substrates. Non-planar In0.53Ga0.47As FinFETs were developed using both "gate-first" and "gate-last" fabrication methods for n-channel MOSFETs. Electron beam lithography and anisotropic plasma etching processes were optimized to create highly scaled fins with near vertical sidewalls. Plasma damage was removed using a wet etch process and improvements in gate efficiency were characterized on MOS capacitor structures. A two-step, selective removal of the pre-grown n+ contact layer was developed for "gate-last" recess etching. The final In0.53Ga 0.47As FinFET devices demonstrated an ION = 70 mA/mm, I ON/IOFF ratio = 15,700 and sub-threshold swing = 210 mV/dec. Bulk GaSb and strained In0.36Ga0.64Sb quantum well (QW) heterostructures were developed for p-channel MOSFETs. Dit was reduced to 2 - 3 x 1012 cm-2eV-1 using an InAs surface layer, (NH4)2S passivation and atomic layer deposition (ALD) of Al2O3. A self-aligned "gate-first" In0.36Ga0.64Sb MOSFET fabrication process was invented using a "T-shaped" electron beam resist patterning stack and intermetallic source/drain contacts. Ni contacts annealed at 300°C demonstrated an ION = 166 mA/mm, ION/IOFF ratio = 1

Compilation of fatigue, fatigue-crack propagation, and fracture data for 2024 and 7075 aluminum, Ti-6Al-4V titanium, and 300M steel. Volume 1: Description of data and data storage on magnetic tape. Volume 2: Data tape (7-track magnetic tape)

NASA Technical Reports Server (NTRS)

Rice, R. C.; Reynolds, J. L.

1976-01-01

Fatigue, fatigue-crack-propagation, and fracture data compiled and stored on magnetic tape are documented. Data for 202 and 7075 aluminum alloys, Ti-6Al-4V titanium alloy, and 300M steel are included in the compilation. Approximately 4,500 fatigue, 6,500 fatigue-crack-propagation, and 1,500 fracture data points are stored on magnetic tape. Descriptions of the data, an index to the data on the magnetic tape, information on data storage format on the tape, a listing of all data source references, and abstracts of other pertinent test information from each data source reference are included.

32 CFR 700.815 - Deaths.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Deaths. 700.815 Section 700.815 National Defense... § 700.815 Deaths. The commanding officer, in the event of the death of any person within his or her command, shall ensure that the cause of death and the circumstances under which death occurred are...

25 CFR 700.257 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... the Commission including, but not limited to, education, financial transactions, medical history, and... 25 Indians 2 2011-04-01 2011-04-01 false Definitions. 700.257 Section 700.257 Indians THE OFFICE... § 700.257 Definitions. (a) Act. As used in this subpart, “Act” means section 3 of the Privacy Act, 5 U.S...

25 CFR 700.251 - Fees.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Fees. 700.251 Section 700.251 Indians THE OFFICE OF... § 700.251 Fees. (a) Services for which fees may be charged. (1) Unless waived pursuant to the provisions of paragraph (c) of this section, user fees shall be charged for document search and duplication...

32 CFR 700.815 - Deaths.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Deaths. 700.815 Section 700.815 National Defense... § 700.815 Deaths. The commanding officer, in the event of the death of any person within his or her command, shall ensure that the cause of death and the circumstances under which death occurred are...

32 CFR 700.815 - Deaths.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Deaths. 700.815 Section 700.815 National Defense... § 700.815 Deaths. The commanding officer, in the event of the death of any person within his or her command, shall ensure that the cause of death and the circumstances under which death occurred are...

32 CFR 700.815 - Deaths.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Deaths. 700.815 Section 700.815 National Defense... § 700.815 Deaths. The commanding officer, in the event of the death of any person within his or her command, shall ensure that the cause of death and the circumstances under which death occurred are...

32 CFR 700.815 - Deaths.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Deaths. 700.815 Section 700.815 National Defense... § 700.815 Deaths. The commanding officer, in the event of the death of any person within his or her command, shall ensure that the cause of death and the circumstances under which death occurred are...

7 CFR 51.700 - Discoloration.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 2 2011-01-01 2011-01-01 false Discoloration. 51.700 Section 51.700 Agriculture... § 51.700 Discoloration. Discoloration means russeting of light shade of golden brown caused by rust... scars or other means may be allowed on a greater area, or darker shades may be allowed on a lesser area...

7 CFR 51.700 - Discoloration.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Discoloration. 51.700 Section 51.700 Agriculture... § 51.700 Discoloration. Discoloration means russeting of light shade of golden brown caused by rust... scars or other means may be allowed on a greater area, or darker shades may be allowed on a lesser area...

New Insulin Glargine 300 Units/mL Versus Glargine 100 Units/mL in People With Type 1 Diabetes: A Randomized, Phase 3a, Open-Label Clinical Trial (EDITION 4).

PubMed

Home, Philip D; Bergenstal, Richard M; Bolli, Geremia B; Ziemen, Monika; Rojeski, Maria; Espinasse, Melanie; Riddle, Matthew C

2015-12-01

Insulin therapy in type 1 diabetes still provides suboptimal outcomes. Insulin glargine 300 units/mL (Gla-300), with a flatter pharmacodynamic profile compared with insulin glargine 100 units/mL (Gla-100), is an approach to this problem. People with type 1 diabetes, using a mealtime and basal insulin regimen, were randomized open-label to Gla-300 or Gla-100 and to morning or evening injection, continuing the mealtime analog, and followed for 6 months. Participants (n = 549) were a mean age of 47 years and had a mean duration of diabetes of 21 years and BMI of 27.6 kg/m(2). The change in HbA1c (primary end point; baseline 8.1%) was equivalent in the two treatment groups (difference, 0.04% [95% CI -0.10 to 0.19]) (0.4 mmol/mol [-1.1 to 2.1]), and Gla-300 was thus noninferior. Similar results with wider 95% CIs were found for morning and evening injection times and for prebreakfast self-measured plasma glucose (SMPG) overall. Results were also similar for Gla-300 when morning and evening injection time was compared, including overlapping 8-point SMPG profiles. Hypoglycemia did not differ, except for the first 8 weeks of the study, when nocturnal confirmed or severe hypoglycemia was lower with Gla-300 (rate ratio 0.69 [95% CI 0.53-0.91]). Hypoglycemia with Gla-300 did not differ by time of injection. The basal insulin dose was somewhat higher at 6 months for Gla-300. The adverse event profile did not differ and was independent of the Gla-300 time of injection. Weight gain was lower with Gla-300. In long-duration type 1 diabetes, Gla-300 provides similar glucose control to Gla-100, with a lower risk of hypoglycemia after transfer from other insulins, independent of time of injection, and less weight gain. © 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Heat transfer at a sapphire - indium interface in the 30 mK - 300 mK temperature range

NASA Astrophysics Data System (ADS)

Liberadzka, J.; Koettig, T.; Bremer, J.; van der Post, C. C. W.; ter Brake, H. J. M.

2017-02-01

Within the framework of the AEgIS (Antimatter Experiment: Gravity, Interferometry, Spectroscopy) project a direct measurement of the Earth’s gravitational acceleration on antihydrogen will be carried out. In order to obtain satisfactory precision of the measurement, the thermal movement of the particles should be reduced. Therefore a Penning trap, which is used to trap antiprotons and create antihydrogen, will be placed on a mixing chamber of an especially designed dilution refrigerator. The trap consists of 10 electrodes, which need to be electrically insulated, but thermally anchored. To ensure that the trap remains at a temperature below 100 mK, the heat transfer at the metallic-dielectric boundary is investigated. A copper - indium - sapphire - indium - copper sandwich setup was mounted on the CERN Cryolab dilution refrigerator. Keeping the mixing chamber at a constant low temperature in the range of 30 mK to 300 mK, steady-state measurements with indium in normal conducting and superconducting states have been performed. Obtained results along with a precise description of our setup are presented.

Decolourization of 4-Chloro-2-Nitrophenol by a Soil Bacterium, Bacillus subtilis RKJ 700

PubMed Central

Arora, Pankaj Kumar

2012-01-01

A 4-Chloro-2-nitrophenol (4C2NP) decolourizing strain RKJ 700 was isolated from soil collected from a pesticide contaminated site of India and identified as Bacillus subtilis on the basis of the 16S rRNA gene sequence analysis. Bacillus subtilis RKJ 700 decolourized 4C2NP up to concentration of 1.5 mM in the presence of additional carbon source. The degradation pathway of 4C2NP was studied and 4-chloro-2-aminophenol, 4-chloro-2-acetaminophenol and 5-chloro-2-methylbenzoxazole (5C2MBZ) were identified as metabolites by high performance liquid chromatography and gas chromatography-mass spectrometry. Resting cell studies showed that Bacillus subtilis RKJ 700 depleted 4C2NP completely with stoichiometric formation of 5C2MBZ. This is the first report of (i) the degradation of 4C2NP at high concentration (1.5 mM) and, (ii) the formation of 5C2MBZ by a soil bacterium. PMID:23251673

Decolourization of 4-chloro-2-nitrophenol by a soil bacterium, Bacillus subtilis RKJ 700.

PubMed

Arora, Pankaj Kumar

2012-01-01

A 4-Chloro-2-nitrophenol (4C2NP) decolourizing strain RKJ 700 was isolated from soil collected from a pesticide contaminated site of India and identified as Bacillus subtilis on the basis of the 16S rRNA gene sequence analysis. Bacillus subtilis RKJ 700 decolourized 4C2NP up to concentration of 1.5 mM in the presence of additional carbon source. The degradation pathway of 4C2NP was studied and 4-chloro-2-aminophenol, 4-chloro-2-acetaminophenol and 5-chloro-2-methylbenzoxazole (5C2MBZ) were identified as metabolites by high performance liquid chromatography and gas chromatography-mass spectrometry. Resting cell studies showed that Bacillus subtilis RKJ 700 depleted 4C2NP completely with stoichiometric formation of 5C2MBZ. This is the first report of (i) the degradation of 4C2NP at high concentration (1.5 mM) and, (ii) the formation of 5C2MBZ by a soil bacterium.

20 CFR 637.300 - Management systems, reporting and recordkeeping.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Management systems, reporting and recordkeeping. 637.300 Section 637.300 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROGRAMS UNDER TITLE V OF THE JOB TRAINING PARTNERSHIP ACT Additional Title V Administrative...

20 CFR 637.300 - Management systems, reporting and recordkeeping.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Management systems, reporting and recordkeeping. 637.300 Section 637.300 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR PROGRAMS UNDER TITLE V OF THE JOB TRAINING PARTNERSHIP ACT Additional Title V Administrative...

Effects of pyrolysis temperature on soybean stover- and peanut shell-derived biochar properties and TCE adsorption in water.

PubMed

Ahmad, Mahtab; Lee, Sang Soo; Dou, Xiaomin; Mohan, Dinesh; Sung, Jwa-Kyung; Yang, Jae E; Ok, Yong Sik

2012-08-01

Conversion of crop residues into biochars (BCs) via pyrolysis is beneficial to environment compared to their direct combustion in agricultural field. Biochars developed from soybean stover at 300 and 700 °C (S-BC300 and S-BC700, respectively) and peanut shells at 300 and 700 °C (P-BC300 and P-BC700, respectively) were used for the removal of trichloroethylene (TCE) from water. Batch adsorption experiments showed that the TCE adsorption was strongly dependent on the BCs properties. Linear relationships were obtained between sorption parameters (K(M) and S(M)) and molar elemental ratios as well as surface area of the BCs. The high adsorption capacity of BCs produced at 700 °C was attributed to their high aromaticity and low polarity. The efficacy of S-BC700 and P-BC700 for removing TCE from water was comparable to that of activated carbon (AC). Pyrolysis temperature influencing the BC properties was a critical factor to assess the removal efficiency of TCE from water. Copyright © 2012 Elsevier Ltd. All rights reserved.

Elastic electron differential cross sections for argon atom in the intermediate energy range from 40 eV to 300 eV

NASA Astrophysics Data System (ADS)

Ranković, Miloš Lj.; Maljković, Jelena B.; Tökési, Károly; Marinković, Bratislav P.

2018-02-01

Measurements and calculations for electron elastic differential cross sections (DCS) of argon atom in the energy range from 40 to 300 eV are presented. DCS have been measured in the crossed beam arrangement of the electron spectrometer with an energy resolution of 0.5 eV and angular resolution of 1.5∘ in the range of scattering angles from 20∘ to 126∘. Both angular behaviour and energy dependence of DCS are obtained in a separate sets of experiments, while the absolute scale is achieved via relative flow method, using helium as a reference gas. All data is corrected for the energy transmission function, changes of primary electron beam current and target pressure, and effective path length (volume correction). DCSs are calculated in relativistic framework by expressing the Mott's cross sections in partial wave expansion. Our results are compared with other available data.

25 CFR 700.83 - Nonprofit organization.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Nonprofit organization. 700.83 Section 700.83 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.83 Nonprofit organization. The term nonprofit organization...

Physiological and technical commitment during a 300-m in-line skating trial in athletes of different age categories.

PubMed

Invernizzi, Pietro L; Scurati, Raffaele; Crotti, Matteo; Bosio, Andrea; Longo, Stefano; Esposito, Fabio

2018-01-04

This study investigated the differences in strength, technique and time performance in in-line skaters of three age categories during a 300 m trial. Possible correlations among these variables were also assessed. Thirty-six elite in-line skaters (Cadets, Juniors and Seniors, n=12 each; 14±1, 16±1, and 24±6 years of age, respectively) performed a 300-m trial on an outdoor oval track. Total time (Ttot), 100-m fractions and duration of each skating technique (initial acceleration phase, straight push and cross-over) were recorded. A squat jump (SJ) was performed before and after the trial. Heart rate, blood lactate concentration ([La-]) and rate of perceived exertion (RPE) were collected before, during and at the end of the trial. Ttot was longer and SJ lower in Cadets compared to the other groups. Seniors employed the cross-over technique for a longer period than the straight push technique, compared to Juniors and Cadets. Ttot correlated negatively with SJ in Seniors. The number of significant correlations between skating techniques' duration and both Ttot and SJ increased with age category. No differences among groups were found for heart rate, [La-] and RPE. With increasing age category, leg strength appeared to be the more related aspect to skating performance. To improve 300-m in-line skating performance, trainers should pay particular attention to the enhancement of leg strength and cross-over skating technique.

Photothermal deflection technique investigation of annealing temperature and time effects on optical and thermal conductivity of V/V2O5 alternating layers structure

NASA Astrophysics Data System (ADS)

Khalfaoui, A.; Ilahi, S.; Abdel-Rahman, M.; Zia, M. F.; Alduraibi, M.; Ilahi, B.; Yacoubi, N.

2017-10-01

The VxOy material is fabricated by alternating multilayer of V/V2O5. Two sets of VxOy are presented annealed at 300 °C and 400 °C for 20, 30 and 40 min. We have determined optical absorption spectra of the two sets by comparison between experimental and theoretical PDS amplitude signal. In fact, a variation of the bandgap energy from 2.34eV to 2.49 eV has found for both set annealed at 300 °C and 400 °C for various annealing time. The variation of bandgap energy is discussed testifying a structural and compositional change. Moreover, thermal conductivity of the set annealed at 400 °C showed a variation from 1.96 W/m K to 6.2 W/m K noting a decrease up to 2.89 W/m K for that annealed for 30 min.

25 CFR 700.467 - Construction costs.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Construction costs. 700.467 Section 700.467 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.467 Construction costs. Construction costs and costs relating to construction such as...

25 CFR 700.467 - Construction costs.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Construction costs. 700.467 Section 700.467 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.467 Construction costs. Construction costs and costs relating to construction such as...

25 CFR 700.467 - Construction costs.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Construction costs. 700.467 Section 700.467 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.467 Construction costs. Construction costs and costs relating to construction such as...

Sustained >100 MeV Gamma-Ray Emission: A Monitor for >300 MeV SEP Protons at the Sun

NASA Astrophysics Data System (ADS)

Share, G. H.; Murphy, R. J.

2017-12-01

Solar γ radiation is the product of proton and ion interactions in the solar atmosphere. The spectrum and temporal characteristics of the emission provides fundamental information on the ions at the Sun. Until the launch of the Fermi satellite, with its Large Area Telescope (LAT) sensitive to radiation above 100 MeV, most of the γ-ray observations were made in the nuclear energy range with radiation arising from interaction of one to tens of MeV ions produced in solar flares. Since 2008 the LAT has detected 30 high-energy γ-ray events with temporal and spectral characteristics that are distinct from the associated solar flare. We call this radiation Sustained Gamma-Ray Emission (SGRE) and briefly summarize its characteristics reported in a recent paper. The γ-ray spectra are consistent with pion decay radiation produced by protons above 300 MeV. The onset of the radiation most often occurs after the impulsive flare and the emission can last several hours. We find that the number of protons responsible for the SGRE is typically more than 10 times the number of flare-accelerated protons. These characteristics require that there be an additional source of energy to accelerate the protons to hundreds of MeV to produce the SGRE. As 28 of the 30 SGRE events are accompanied by fast CMEs, it is likely that these protons are accelerated by the same shock that produces gradual SEPs. We find that the number of protons >500 MeV in the accompanying SEPs is typically about 50-100 times the number of protons that return to the Sun to produce the SGRE. There also appear to be correlations between the numbers of SEP and SGRE protons and durations of >100 MeV SEP proton and SGRE events. We find that for all SGRE events where there were flare observations, the accompanying impulsive X-radiation reached energies >100 keV. In a limited study of 18 solar events with CME speeds >800 km/s we also find that the median SEP proton flux is 25 times higher when flare hard X-rays exceed 100

Images of liposarcoma using technetium-99m bleomycin and technetium (V)-99m DMSA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohta, H.; Shane, F.I.; Endo, K.

1986-12-01

The effectiveness of Tc-99m bleomycin (BLM) and Tc(V)-99m DMSA are compared with that of Ga-67 citrate, which is currently the most widely used agent. In four patients with lipomatous tumors, the clinical significance of tumor imaging with each of these three agents is discussed and compared. Results indicate that both Tc-99m BLM and Tc(V)-99m DMSA are superior in detecting the extension or localization of liposarcomas.

16 CFR 700.1 - Products covered.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., those agricultural products normally used for personal or household gardening (for example, to produce... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Products covered. 700.1 Section 700.1... MAGNUSON-MOSS WARRANTY ACT INTERPRETATIONS OF MAGNUSON-MOSS WARRANTY ACT § 700.1 Products covered. (a) The...

16 CFR 700.1 - Products covered.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., those agricultural products normally used for personal or household gardening (for example, to produce... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Products covered. 700.1 Section 700.1... MAGNUSON-MOSS WARRANTY ACT INTERPRETATIONS OF MAGNUSON-MOSS WARRANTY ACT § 700.1 Products covered. (a) The...

16 CFR 700.1 - Products covered.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., those agricultural products normally used for personal or household gardening (for example, to produce... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Products covered. 700.1 Section 700.1... MAGNUSON-MOSS WARRANTY ACT INTERPRETATIONS OF MAGNUSON-MOSS WARRANTY ACT § 700.1 Products covered. (a) The...

16 CFR 700.1 - Products covered.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., those agricultural products normally used for personal or household gardening (for example, to produce... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Products covered. 700.1 Section 700.1... MAGNUSON-MOSS WARRANTY ACT INTERPRETATIONS OF MAGNUSON-MOSS WARRANTY ACT § 700.1 Products covered. (a) The...

25 CFR 700.549 - Employee organizations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Employee organizations. 700.549 Section 700.549 Indians... Employee Responsibility and Conduct § 700.549 Employee organizations. An employee may not knowingly be a member of an organization of Government employees that advocates the overthrow of the United States...

14 CFR 1212.700 - NASA employees.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false NASA employees. 1212.700 Section 1212.700 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS NASA Authority and Responsibilities § 1212.700 NASA employees. (a) Each NASA employee is responsible for adhering...

14 CFR 1212.700 - NASA employees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true NASA employees. 1212.700 Section 1212.700 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS NASA Authority and Responsibilities § 1212.700 NASA employees. (a) Each NASA employee is responsible for adhering...

14 CFR 1212.700 - NASA employees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false NASA employees. 1212.700 Section 1212.700 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS NASA Authority and Responsibilities § 1212.700 NASA employees. (a) Each NASA employee is responsible for adhering...

14 CFR 1212.700 - NASA employees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false NASA employees. 1212.700 Section 1212.700 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS NASA Authority and Responsibilities § 1212.700 NASA employees. (a) Each NASA employee is responsible for adhering...

32 CFR 700.826 - Physical security.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Physical security. 700.826 Section 700.826 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Commanding Officers in General § 700.826 Physical security. (a) The commanding officer shall take appropriate...

32 CFR 700.826 - Physical security.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Physical security. 700.826 Section 700.826 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Commanding Officers in General § 700.826 Physical security. (a) The commanding officer shall take appropriate...

32 CFR 700.826 - Physical security.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Physical security. 700.826 Section 700.826 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Commanding Officers in General § 700.826 Physical security. (a) The commanding officer shall take appropriate...

32 CFR 700.826 - Physical security.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Physical security. 700.826 Section 700.826 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Commanding Officers in General § 700.826 Physical security. (a) The commanding officer shall take appropriate...

32 CFR 700.826 - Physical security.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Physical security. 700.826 Section 700.826 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Commanding Officers in General § 700.826 Physical security. (a) The commanding officer shall take appropriate...

25 CFR 700.93 - Relocation plan.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Relocation plan. 700.93 Section 700.93 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.93 Relocation plan. The relocation plan shall be the plan prepared...

32 CFR 700.832 - Environmental pollution.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Environmental pollution. 700.832 Section 700.832... Commanding Officers in General § 700.832 Environmental pollution. The commanding officer shall cooperate with... environmental pollution. If the requirements of any environmental law cannot be achieved because of operational...

32 CFR 700.832 - Environmental pollution.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Environmental pollution. 700.832 Section 700.832... Commanding Officers in General § 700.832 Environmental pollution. The commanding officer shall cooperate with... environmental pollution. If the requirements of any environmental law cannot be achieved because of operational...

A 190 mV start-up and 59.2% efficiency CMOS gate boosting voltage doubler charge pump in 0.18 µm standard CMOS process for energy harvesting

NASA Astrophysics Data System (ADS)

Yoshida, Minori; Miyaji, Kousuke

2018-04-01

A start-up charge pump circuit for an extremely low input voltage (V IN) is proposed and demonstrated. The proposed circuit uses an inverter level shifter to generate a 2V IN voltage swing to the gate of both main NMOS and PMOS power transistors in a charge pump to reduce the channel resistance. The proposed circuit is fully implemented in a standard 0.18 µm CMOS process, and the measurement result shows that a minimum input voltage of 190 mV is achieved and output power increases by 181% compared with the conventional forward-body-bias scheme at a 300 mV input voltage. The proposed scheme achieves a maximum efficiency of 59.2% when the input voltage is 390 mV and the output current is 320 nA. The proposed circuit is suitable as a start-up circuit in ultralow power energy harvesting power management applications to boost-up from below threshold voltage.

25 CFR 700.479 - Administrative review.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Administrative review. 700.479 Section 700.479 Indians... Discretionary Funds § 700.479 Administrative review. (a) If the Commissioners determine that implementation of... is terminated or suspended under paragraph (b) of this section may request a review of such action by...

25 CFR 700.561 - Sexual harassment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Sexual harassment. 700.561 Section 700.561 Indians THE... Responsibility and Conduct § 700.561 Sexual harassment. (a) Sexual harassment is a form of employee misconduct... an environment free from unsolicited and unwelcome sexual overtures. Sexual harassment is defined by...

25 CFR 700.561 - Sexual harassment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Sexual harassment. 700.561 Section 700.561 Indians THE... Responsibility and Conduct § 700.561 Sexual harassment. (a) Sexual harassment is a form of employee misconduct... an environment free from unsolicited and unwelcome sexual overtures. Sexual harassment is defined by...

25 CFR 700.561 - Sexual harassment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Sexual harassment. 700.561 Section 700.561 Indians THE... Responsibility and Conduct § 700.561 Sexual harassment. (a) Sexual harassment is a form of employee misconduct... an environment free from unsolicited and unwelcome sexual overtures. Sexual harassment is defined by...

25 CFR 700.561 - Sexual harassment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Sexual harassment. 700.561 Section 700.561 Indians THE... Responsibility and Conduct § 700.561 Sexual harassment. (a) Sexual harassment is a form of employee misconduct... an environment free from unsolicited and unwelcome sexual overtures. Sexual harassment is defined by...

25 CFR 700.707 - Regulations; scope.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Regulations; scope. 700.707 Section 700.707 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.707 Regulations; scope. The grazing regulations in this part apply to the New Lands within...

25 CFR 700.707 - Regulations; scope.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Regulations; scope. 700.707 Section 700.707 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES New Lands Grazing § 700.707 Regulations; scope. The grazing regulations in this part apply to the New Lands within...

25 CFR 700.51 - Custodial parent.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Custodial parent. 700.51 Section 700.51 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.51 Custodial parent. A custodial parent is a person who has the...

25 CFR 700.99 - Salvage value.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Salvage value. 700.99 Section 700.99 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.99 Salvage value. Salvage value means the probable sale price of an...

15 CFR 700.6 - Official actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Official actions. 700.6 Section 700.6... PRIORITIES AND ALLOCATIONS SYSTEM Overview § 700.6 Official actions. When necessary, Commerce takes specific official actions to implement or enforce the provisions of this regulation and to provide special...

15 CFR 700.6 - Official actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Official actions. 700.6 Section 700.6... PRIORITIES AND ALLOCATIONS SYSTEM Overview § 700.6 Official actions. When necessary, Commerce takes specific official actions to implement or enforce the provisions of this regulation and to provide special...

25 CFR 700.91 - Relocation report.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Relocation report. 700.91 Section 700.91 Indians THE... Policies and Instructions Definitions § 700.91 Relocation report. The relocation report shall be the report prepared by the Commission and submitted to Congress pursuant to section 13(a) of the Act. ...

25 CFR 700.91 - Relocation report.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Relocation report. 700.91 Section 700.91 Indians THE... Policies and Instructions Definitions § 700.91 Relocation report. The relocation report shall be the report prepared by the Commission and submitted to Congress pursuant to section 13(a) of the Act. ...

25 CFR 700.91 - Relocation report.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Relocation report. 700.91 Section 700.91 Indians THE... Policies and Instructions Definitions § 700.91 Relocation report. The relocation report shall be the report prepared by the Commission and submitted to Congress pursuant to section 13(a) of the Act. ...

25 CFR 700.91 - Relocation report.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Relocation report. 700.91 Section 700.91 Indians THE... Policies and Instructions Definitions § 700.91 Relocation report. The relocation report shall be the report prepared by the Commission and submitted to Congress pursuant to section 13(a) of the Act. ...

25 CFR 700.91 - Relocation report.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Relocation report. 700.91 Section 700.91 Indians THE... Policies and Instructions Definitions § 700.91 Relocation report. The relocation report shall be the report prepared by the Commission and submitted to Congress pursuant to section 13(a) of the Act. ...

The 3 H(d , γ) Reaction at Ec . m . <= 300 keV

NASA Astrophysics Data System (ADS)

Parker, C. E.; Brune, C. R.; Massey, T. N.; O'Donnell, J. E.; Richard, A. L.; Sayre, D. B.

2015-04-01

The 3 H(d , γ) 5He reaction has been measured using a 500-keV pulsed deuteron beam incident on a stopping titanium tritide target at the Edwards Accelerator Laboratory. The time-of-flight technique has been used to distinguish the γ-rays from neutrons in the bismuth germinate (BGO) γ-ray detector. A stilbene scintillator and an NE-213 scintillator have been used to detect the neutrons from the 3 H(d , n) α reaction using both the pulse-shape discrimination and time-of-flight techniques. A newly designed target holder with a silicon surface barrier detector to simultaneously measure α-particles to normalize the number of neutrons, along with a new titanium tritide target, was incorporated for subsequent measurements. The γ-rays have been measured at laboratory angles of 0 °, 45 °, 90 °, and 135 °. Information about the γ-ray energy distribution for the unbound ground state and first excited state of 5He can be obtained experimentally by comparing the BGO data to Monte Carlo simulations. The 3 H(d , γ) /3 H(d , n) branching ratio has also been measured. Data analysis is currently underway for the subsequent measurements. This work is supported in part by Lawrence Livermore National Laboratory and the U.S. D.O.E. (NNSA) through Grant No. DE-NA0001837.

28 CFR 700.10 - General provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false General provisions. 700.10 Section 700.10... Privacy Act of 1974 § 700.10 General provisions. (a) Purpose and scope. The subpart contains the... pertaining to him, may request correction of such records, or may seek an accounting of disclosures of such...

25 CFR 700.717 - Stocking rate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Stocking rate. 700.717 Section 700.717 Indians THE OFFICE... Grazing § 700.717 Stocking rate. The Commissioner will determine livestock carrying capacity for each range unit and set the stocking rate and adjust that rate as conditions warrant. The Commissioner may...

25 CFR 700.717 - Stocking rate.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Stocking rate. 700.717 Section 700.717 Indians THE OFFICE... Grazing § 700.717 Stocking rate. The Commissioner will determine livestock carrying capacity for each range unit and set the stocking rate and adjust that rate as conditions warrant. The Commissioner may...

25 CFR 700.717 - Stocking rate.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Stocking rate. 700.717 Section 700.717 Indians THE OFFICE... Grazing § 700.717 Stocking rate. The Commissioner will determine livestock carrying capacity for each range unit and set the stocking rate and adjust that rate as conditions warrant. The Commissioner may...

25 CFR 700.717 - Stocking rate.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Stocking rate. 700.717 Section 700.717 Indians THE OFFICE... Grazing § 700.717 Stocking rate. The Commissioner will determine livestock carrying capacity for each range unit and set the stocking rate and adjust that rate as conditions warrant. The Commissioner may...

25 CFR 700.531 - Government property.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and for...

25 CFR 700.531 - Government property.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and for...

25 CFR 700.531 - Government property.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and for...

25 CFR 700.531 - Government property.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and for...

25 CFR 700.531 - Government property.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Government property. 700.531 Section 700.531 Indians THE... Responsibility and Conduct § 700.531 Government property. Employees shall be held accountable for Government... employee has a positive duty to protect and conserve Government property and to use it economically and for...

Design of a 300-kV gas environmental transmission electron microscope equipped with a cold field emission gun.

PubMed

Isakozawa, Shigeto; Nagaoki, Isao; Watabe, Akira; Nagakubo, Yasuhira; Saito, Nobuhiro; Matsumoto, Hiroaki; Zhang, Xiao Feng; Taniguchi, Yoshifumi; Baba, Norio

2016-08-01

A new in situ environmental transmission electron microscope (ETEM) was developed based on a 300 kV TEM with a cold field emission gun (CFEG). Particular caution was taken in the ETEM design to assure uncompromised imaging and analytical performance of the TEM. Because of the improved pumping system between the gun and column, the vacuum of CFEG was largely improved and the probe current was sufficiently stabilized to operate without tip flashing for 2-3 h or longer. A high brightness of 2.5 × 10(9) A/cm(2) sr was measured at 300 kV, verifying the high quality of the CFEG electron beam. A specially designed gas injection-heating holder was used in the in situ TEM study at elevated temperatures with or without gas around the TEM specimen. Using this holder in a 10 Pa gas atmosphere and specimen temperatures up to 1000°C, high-resolution ETEM performance and analysis were achieved. © The Author 2016. Published by Oxford University Press on behalf of The Japanese Society of Microscopy. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

SAGE II V7.00 Release Notes

Atmospheric Science Data Center

2013-02-21

... algorithms from SAGE III v4.00 Ceased removal of the water vapor extinction in the 600nm channel due to uncertainty in the H2O ... within the main aerosol layer generally reflecting excellent quality in previous versions. There is some minor decrease in extinction at ...

A compact 300 kV solid-state high-voltage nanosecond generator for dielectric wall accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, Yi; Wang, Wei; Liu, Yi

2015-05-15

Compact solid-state system is the main development trend in pulsed power technologies. A compact solid-state high-voltage nanosecond pulse generator with output voltage of 300 kV amplitude, 10 ns duration (FWHM), and 3 ns rise-time was designed for a dielectric wall accelerator. The generator is stacked by 15 planar-plate Blumlein pulse forming lines (PFL). Each Blumlein PFL consists of two solid-state planar transmission lines, a GaAs photoconductive semiconductor switch, and a laser diode trigger. The key components of the generator and the experimental results are reported in this paper.

25 CFR 700.725 - Livestock trespass.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Livestock trespass. 700.725 Section 700.725 Indians THE... Grazing § 700.725 Livestock trespass. The following acts are prohibited: (a) The grazing of livestock upon... Management Plan. The owner of any livestock grazing in trespass on the New Lands is liable to a civil penalty...

25 CFR 700.725 - Livestock trespass.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Livestock trespass. 700.725 Section 700.725 Indians THE... Grazing § 700.725 Livestock trespass. The following acts are prohibited: (a) The grazing of livestock upon... Management Plan. The owner of any livestock grazing in trespass on the New Lands is liable to a civil penalty...

25 CFR 700.725 - Livestock trespass.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Livestock trespass. 700.725 Section 700.725 Indians THE... Grazing § 700.725 Livestock trespass. The following acts are prohibited: (a) The grazing of livestock upon... Management Plan. The owner of any livestock grazing in trespass on the New Lands is liable to a civil penalty...

25 CFR 700.725 - Livestock trespass.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Livestock trespass. 700.725 Section 700.725 Indians THE... Grazing § 700.725 Livestock trespass. The following acts are prohibited: (a) The grazing of livestock upon... Management Plan. The owner of any livestock grazing in trespass on the New Lands is liable to a civil penalty...

Underwater Mapping Results for Seabotix vLBV300 Vehicle with Tritech Gemini 720i Imaging Sonar near Newport, OR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hollinger, Geoffrey

This document presents results from tests to demonstrate underwater mapping capabilities of an underwater vehicle in conditions typically found in marine renewable energy arrays. These tests were performed with a tethered Seabotix vLBV300 underwater vehicle. The vehicle is equipped with an inertial navigation system (INS) based on a Gladiator Landmark 40 IMU and Teledyne Explorer Doppler Velocity Log, as well as a Gemini 720i scanning sonar acquired from Tritech. The results presented include both indoor pool and offshore deployments. The indoor pool deployments were performed on October 7, 2016 and February 3, 2017 in Corvallis, OR. The offshore deployment wasmore » performed on April 20, 2016 off the coast of Newport, OR (44.678 degrees N, 124.109 degrees W). During the mission period, the sea state varied between 3 and 4, with an average significant wave height of 1.6 m. Data was recorded from both the INS and the sonar.« less

48 CFR 23.700 - Scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Scope. 23.700 Section 23.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

48 CFR 23.700 - Scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Scope. 23.700 Section 23.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

48 CFR 23.700 - Scope.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Scope. 23.700 Section 23.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

48 CFR 23.700 - Scope.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Scope. 23.700 Section 23.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE...

15 CFR 700.11 - Priority ratings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... DO-A1 or DX-A1 priority rating. A contract for a radar set will contain a DO-A7 or DX-A7 priority... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Priority ratings. 700.11 Section 700... DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.11 Priority ratings. (a) Levels of...

17 CFR 300.300 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section 8(e...

17 CFR 300.300 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section 8(e...

17 CFR 300.300 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section 8(e...

17 CFR 300.300 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Definitions. 300.300 Section 300.300 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) Schedule A... Contractual Commitments § 300.300 Definitions. For the purpose of these rules, adopted pursuant to section 8(e...

Benchmarking passive seismic methods of estimating the depth of velocity interfaces down to ~300 m

NASA Astrophysics Data System (ADS)

Czarnota, Karol; Gorbatov, Alexei

2016-04-01

In shallow passive seismology it is generally accepted that the spatial autocorrelation (SPAC) method is more robust than the horizontal-over-vertical spectral ratio (HVSR) method at resolving the depth to surface-wave velocity (Vs) interfaces. Here we present results of a field test of these two methods over ten drill sites in western Victoria, Australia. The target interface is the base of Cenozoic unconsolidated to semi-consolidated clastic and/or carbonate sediments of the Murray Basin, which overlie Paleozoic crystalline rocks. Depths of this interface intersected in drill holes are between ~27 m and ~300 m. Seismometers were deployed in a three-arm spiral array, with a radius of 250 m, consisting of 13 Trillium Compact 120 s broadband instruments. Data were acquired at each site for 7-21 hours. The Vs architecture beneath each site was determined through nonlinear inversion of HVSR and SPAC data using the neighbourhood algorithm, implemented in the geopsy modelling package (Wathelet, 2005, GRL v35). The HVSR technique yielded depth estimates of the target interface (Vs > 1000 m/s) generally within ±20% error. Successful estimates were even obtained at a site with an inverted velocity profile, where Quaternary basalts overlie Neogene sediments which in turn overlie the target basement. Half of the SPAC estimates showed significantly higher errors than were obtained using HVSR. Joint inversion provided the most reliable estimates but was unstable at three sites. We attribute the surprising success of HVSR over SPAC to a low content of transient signals within the seismic record caused by low levels of anthropogenic noise at the benchmark sites. At a few sites SPAC waveform curves showed clear overtones suggesting that more reliable SPAC estimates may be obtained utilizing a multi-modal inversion. Nevertheless, our study indicates that reliable basin thickness estimates in the Australian conditions tested can be obtained utilizing HVSR data from a single

Crop suitability monitoring for improved yield estimations with 100m PROBA-V data

NASA Astrophysics Data System (ADS)

Özüm Durgun, Yetkin; Gilliams, Sven; Gobin, Anne; Duveiller, Grégory; Djaby, Bakary; Tychon, Bernard

2015-04-01

This study has been realised within the framework of a PhD targeting to advance agricultural monitoring with improved yield estimations using SPOT VEGETATION remotely sensed data. For the first research question, the aim was to improve dry matter productivity (DMP) for C3 and C4 plants by adding a water stress factor. Additionally, the relation between the actual crop yield and DMP was studied. One of the limitations was the lack of crop specific maps which leads to the second research question on 'crop suitability monitoring'. The objective of this work is to create a methodological approach based on the spectral and temporal characteristics of PROBA-V images and ancillary data such as meteorology, soil and topographic data to improve the estimation of annual crop yields. The PROBA-V satellite was launched on 6th May 2013, and was designed to bridge the gap in space-borne vegetation measurements between SPOT-VGT (March 1998 - May 2014) and the upcoming Sentinel-3 satellites scheduled for launch in 2015/2016. PROBA -V has products in four spectral bands: BLUE (centred at 0.463 µm), RED (0.655 µm), NIR (0.845 µm), and SWIR (1.600 µm) with a spatial resolution ranging from 1km to 300m. Due to the construction of the sensor, the central camera can provide a 100m data product with a 5 to 8 days revisiting time. Although the 100m data product is still in test phase a methodology for crop suitability monitoring was developed. The multi-spectral composites, NDVI (Normalised Difference Vegetation Index) (NIR_RED/NIR+RED) and NDII (Normalised Difference Infrared Index) (NIR-SWIR/NIR+SWIR) profiles are used in addition to secondary data such as digital elevation data, precipitation, temperature, soil types and administrative boundaries to improve the accuracy of crop yield estimations. The methodology is evaluated on several FP7 SIGMA test sites for the 2014 - 2015 period. Reference data in the form of vector GIS with boundaries and cover type of agricultural fields are

50 CFR 300.37 - Radio monitoring.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182 mHz...

50 CFR 300.37 - Radio monitoring.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182 mHz...

50 CFR 300.37 - Radio monitoring.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182 mHz...

50 CFR 300.37 - Radio monitoring.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182 mHz...

50 CFR 300.37 - Radio monitoring.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Radio monitoring. 300.37 Section 300.37 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.37 Radio monitoring. The international distress frequency, 2.182 mHz...

15 CFR 700.62 - Directives.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Directives. 700.62 Section 700.62 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE...

34 CFR 300.300 - Parental consent.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and 300...

34 CFR 300.300 - Parental consent.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and 300...

34 CFR 300.300 - Parental consent.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and 300...

34 CFR 300.300 - Parental consent.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true Parental consent. 300.300 Section 300.300 Education... Placements Parental Consent § 300.300 Parental consent. (a) Parental consent for initial evaluation. (1)(i... child with a disability under § 300.8 must, after providing notice consistent with §§ 300.503 and 300...

Eleventh Annual V. M. Goldschmidt Conference

NASA Technical Reports Server (NTRS)

2001-01-01

This CD-ROM contains the abstracts and associated files for the Eleventh Annual V.M Goldschmidt Conference. Topics include: Organic Geochemistry; Metamorphic Processes; Igneous Processes; Stable and Radiogenic Isotopes; Planetary Geochemistry and Mineralogy; Mineralogy and Crystallography; Ore Deposits; and Aqueous Geochemistry.

42 CFR 456.700 - Scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ASSISTANCE PROGRAMS UTILIZATION CONTROL Drug Use Review (DUR) Program and Electronic Claims Management System... optional point-of-sale electronic claims management system for processing claims for covered outpatient... 42 Public Health 4 2014-10-01 2014-10-01 false Scope. 456.700 Section 456.700 Public Health...

15 CFR 700.81 - Appeals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE..., or other relevant information and documents available to the Department of Commerce, or consult with... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Appeals. 700.81 Section 700.81...

25 CFR 700.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Purpose. 700.1 Section 700.1 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and... the disproportionate adverse, social, economic, cultural and other impacts of relocation. (b) To set...

42 CFR 456.700 - Scope.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 4 2012-10-01 2012-10-01 false Scope. 456.700 Section 456.700 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Drug Use Review (DUR) Program and Electronic Claims Management System...

Comparison of Insulin Glargine 300 Units/mL and 100 Units/mL in Adults With Type 1 Diabetes: Continuous Glucose Monitoring Profiles and Variability Using Morning or Evening Injections.

PubMed

Bergenstal, Richard M; Bailey, Timothy S; Rodbard, David; Ziemen, Monika; Guo, Hailing; Muehlen-Bartmer, Isabel; Ahmann, Andrew J

2017-04-01

The objective of this study was to compare glucose control in participants with type 1 diabetes receiving insulin glargine 300 units/mL (Gla-300) or glargine 100 units/mL (Gla-100) in the morning or evening, in combination with mealtime insulin. In this 16-week, exploratory, open-label, parallel-group, two-period crossover study (clinicaltrials.gov identifier NCT01658579), 59 adults with type 1 diabetes were randomized (1:1:1:1) to once-daily Gla-300 or Gla-100 given in the morning or evening (with crossover in the injection schedule). The primary efficacy end point was the mean percentage of time in the target glucose range (80-140 mg/dL), as measured using continuous glucose monitoring (CGM), during the last 2 weeks of each 8-week period. Additional end points included other CGM glycemic control parameters, hypoglycemia (per self-monitored plasma glucose [SMPG]), and adverse events. The percentage of time within the target glucose range was comparable between the Gla-300 and Gla-100 groups. There was significantly less increase in CGM-based glucose during the last 4 h of the 24-h injection interval for Gla-300 compared with Gla-100 (least squares mean difference -14.7 mg/dL [95% CI -26.9 to -2.5]; P = 0.0192). Mean 24-h glucose curves for the Gla-300 group were smoother (lower glycemic excursions), irrespective of morning or evening injection. Four metrics of intrasubject interstitial glucose variability showed no difference between Gla-300 and Gla-100. Nocturnal confirmed (<54 mg/dL by SMPG) or severe hypoglycemia rate was lower for Gla-300 participants than for Gla-100 participants (4.0 vs. 9.0 events per participant-year; rate ratio 0.45 [95% CI 0.24-0.82]). Less increase in CGM-based glucose levels in the last 4 h of the 24-h injection interval, smoother average 24-h glucose profiles irrespective of injection time, and reduced nocturnal hypoglycemia were observed with Gla-300 versus Gla-100. © 2017 by the American Diabetes Association.

76 FR 49664 - Safety Zone; M/V DAVY CROCKETT, Columbia River

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-11

...-AA00 Safety Zone; M/V DAVY CROCKETT, Columbia River AGENCY: Coast Guard, DHS. ACTION: Temporary final... waters of the Columbia River surrounding the M/ V DAVY CROCKETT at approximate river mile 117. The... operations involving the M/ V DAVY CROCKETT. All persons and vessels are prohibited from entering or...

31 CFR 700.2 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Applicability. 700.2 Section 700.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.13 - Nondiscrimination.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Nondiscrimination. 700.13 Section 700.13 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.2 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Applicability. 700.2 Section 700.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.6 - Nuisances.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Nuisances. 700.6 Section 700.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.6 - Nuisances.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Nuisances. 700.6 Section 700.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.13 - Nondiscrimination.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Nondiscrimination. 700.13 Section 700.13 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.2 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Applicability. 700.2 Section 700.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.6 - Nuisances.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Nuisances. 700.6 Section 700.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.13 - Nondiscrimination.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Nondiscrimination. 700.13 Section 700.13 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.13 - Nondiscrimination.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Nondiscrimination. 700.13 Section 700.13 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.6 - Nuisances.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Nuisances. 700.6 Section 700.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.6 - Nuisances.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Nuisances. 700.6 Section 700.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.2 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Applicability. 700.2 Section 700.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.2 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Applicability. 700.2 Section 700.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

The effect of concomitant DPPIVi use on glycaemic control and hypoglycaemia with insulin glargine 300 U/mL (Gla-300) versus insulin glargine 100 U/mL (Gla-100) in people with type 2 diabetes: A patient-level meta-analysis of EDITION 2 and 3.

PubMed

Yale, Jean-François; Pettus, Jeremy Hodson; Brito-Sanfiel, Miguel; Lavalle-Gonzalez, Fernando; Merino-Trigo, Ana; Stella, Peter; Chevalier, Soazig; Buzzetti, Raffaella

2018-01-01

To evaluate the effect of concomitant dipeptidyl peptidase IV inhibitor (DPPIVi) use on efficacy and safety of insulin glargine 300 U/mL (Gla-300) versus glargine 100 U/mL (Gla-100) in people with type 2 diabetes on oral antihyperglycaemic drugs. A post hoc patient-level meta-analysis was performed using data from EDITION 2 (basal insulin [N = 811]) and EDITION 3 (insulin-naïve [N = 878]), multicentre, randomised, open-label, parallel-group, phase 3a trials of similar design. Endpoints analysed included HbA1c, hypoglycaemia and adverse events, investigated in subgroups of participants with and without concomitant DPPIVi use. Of 1689 participants randomised, 107 (13%, Gla-300) and 133 (16%, Gla-100) received DPPIVi therapy. The least squares mean change in HbA1c (baseline to month 6) was comparable between treatment groups, irrespective of DPPIVi use (no evidence of heterogeneity of treatment effect across subgroups, p = 0.753), although group sizes were unbalanced. The cumulative mean number of confirmed (≤3.9 mmol/L [≤70 mg/dL]) or severe hypoglycaemic events, and the risk and annualised rate of such events, were consistently lower for Gla-300 than Gla-100 during the night (between 00:00 and 05:59 h) or at any time of day (24 h period), irrespective of DPPIVi use. Severe hypoglycaemia occurred in 8/838 and 10/844 participants in the Gla-300 and Gla-100 groups, respectively, and was not affected by DPPIVi use. The adverse event profile was similar between treatment groups and DPPIVi subgroups. Glycaemic control with Gla-300 was comparable to Gla-100, with less hypoglycaemia during the night and at any time of day (24 h), irrespective of concomitant DPPIVi use. ClinicalTrials.gov NCT01499095; NCT01676220.

Oxygen uptake and blood metabolic responses to a 400-m run.

PubMed

Hanon, Christine; Lepretre, Pierre-Marie; Bishop, David; Thomas, Claire

2010-05-01

This study aimed to investigate the oxygen uptake and metabolic responses during a 400-m run reproducing the pacing strategy used in competition. A portable gas analyser was used to measure the oxygen uptake (VO2) of ten specifically trained runners racing on an outdoor track. The tests included (1) an incremental test to determine maximal VO2 (VO2max) and the velocity associated with VO2(max) (v - VO2max), (2) a maximal 400-m (400T) and 3) a 300-m running test (300T) reproducing the exact pacing pattern of the 400T. Blood lactate, bicarbonate concentrations [HCO3(-)], pH and arterial oxygen saturation were analysed at rest and 1, 4, 7, 10 min after the end of the 400 and 300T. The peak VO2 recorded during the 400T corresponded to 93.9 +/- 3.9% of VO2max and was reached at 24.4 +/- 3.2 s (192 +/- 22 m). A significant decrease in VO2 (P < 0.05) was observed in all subjects during the last 100 m, although the velocity did not decrease below v - VO2max. The VO2 in the last 5 s was correlated with the pH (r = 0.86, P < 0.0005) and [HCO3(-)] (r = 0.70, P < 0.05) measured at the end of 300T. Additionally, the velocity decrease observed in the last 100 m was inversely correlated with [HCO3(-)] and pH at 300T (r = -0.83, P < 0.001, r = -0.69, P < 0.05, respectively). These track running data demonstrate that acidosis at 300 m was related to both the VO2 response and the velocity decrease during the final 100 m of a 400-m run.

48 CFR 42.700 - Scope of subpart.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Scope of subpart. 42.700 Section 42.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Indirect Cost Rates 42.700 Scope of subpart. This subpart...

48 CFR 42.700 - Scope of subpart.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Scope of subpart. 42.700 Section 42.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Indirect Cost Rates 42.700 Scope of subpart. This subpart...

48 CFR 42.700 - Scope of subpart.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Scope of subpart. 42.700 Section 42.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Indirect Cost Rates 42.700 Scope of subpart. This subpart...

48 CFR 42.700 - Scope of subpart.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Scope of subpart. 42.700 Section 42.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Indirect Cost Rates 42.700 Scope of subpart. This subpart...

48 CFR 42.700 - Scope of subpart.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Scope of subpart. 42.700 Section 42.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Indirect Cost Rates 42.700 Scope of subpart. This subpart...

48 CFR 32.700 - Scope of subpart.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Scope of subpart. 32.700 Section 32.700 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Contract Funding 32.700 Scope of subpart. This subpart (a) describes basic...

Hemispherical emissivity of V, Nb, Ta, Mo, and W from 300 to 1000 K

NASA Technical Reports Server (NTRS)

Cheng, S. X.; Hanssen, L. M.; Riffe, D. M.; Sievers, A. J.; Cebe, P.

1987-01-01

The hemispherical emissivities of five transition elements, V, Nb, Ta, Mo, and W, have been measured from 300 to 1000 K, complementing earlier higher-temperature results. These low-temperature data, which are similar, are fitted to a Drude model in which the room-temperature parameters have been obtained from optical measurements and the temperature dependence of the dc resistivity is used as input to calculate the temperature dependence of the emissivity. A frequency-dependent free-carrier relaxation rate is found to have a similar magnitude for all these elements. For temperatures larger than 1200 K the calculated emissivity is always greater than the measured value, indicating that the high-temperature interband features of transition elements are much weaker than those determined from room-temperature measurements.

32 CFR 700.402 - Succession.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Succession. 700.402 Section 700.402 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND....402 Succession. When there is a vacancy in the position of Chief of Naval Operations, or during the...

32 CFR 700.402 - Succession.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Succession. 700.402 Section 700.402 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND....402 Succession. When there is a vacancy in the position of Chief of Naval Operations, or during the...

32 CFR 700.402 - Succession.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Succession. 700.402 Section 700.402 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND....402 Succession. When there is a vacancy in the position of Chief of Naval Operations, or during the...

32 CFR 700.402 - Succession.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Succession. 700.402 Section 700.402 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND....402 Succession. When there is a vacancy in the position of Chief of Naval Operations, or during the...

32 CFR 700.402 - Succession.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Succession. 700.402 Section 700.402 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND....402 Succession. When there is a vacancy in the position of Chief of Naval Operations, or during the...

25 CFR 700.79 - Marriage.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Marriage. 700.79 Section 700.79 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and... between a man or woman recognized by the law of the Hopi Tribe or the Navajo Tribe. ...

25 CFR 700.79 - Marriage.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Marriage. 700.79 Section 700.79 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and... between a man or woman recognized by the law of the Hopi Tribe or the Navajo Tribe. ...

25 CFR 700.79 - Marriage.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Marriage. 700.79 Section 700.79 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and... between a man or woman recognized by the law of the Hopi Tribe or the Navajo Tribe. ...

25 CFR 700.79 - Marriage.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Marriage. 700.79 Section 700.79 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and... between a man or woman recognized by the law of the Hopi Tribe or the Navajo Tribe. ...

25 CFR 700.79 - Marriage.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Marriage. 700.79 Section 700.79 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and... between a man or woman recognized by the law of the Hopi Tribe or the Navajo Tribe. ...

21 CFR 700.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Definitions. 700.3 Section 700.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS GENERAL... Food, Drug, and Cosmetic Act. (b) The term cosmetic product means a finished cosmetic the manufacture...

21 CFR 700.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Definitions. 700.3 Section 700.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS GENERAL... Food, Drug, and Cosmetic Act. (b) The term cosmetic product means a finished cosmetic the manufacture...

21 CFR 700.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Definitions. 700.3 Section 700.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS GENERAL... Food, Drug, and Cosmetic Act. (b) The term cosmetic product means a finished cosmetic the manufacture...

Tensile and creep deformation of a newly developed Ni-Fe-based superalloy for 700 °C advanced ultra-supercritical boiler applications

NASA Astrophysics Data System (ADS)

Yuan, Y.; Zhong, Z. H.; Yu, Z. S.; Yin, H. F.; Dang, Y. Y.; Zhao, X. B.; Yang, Z.; Lu, J. T.; Yan, J. B.; Gu, Y.

2015-07-01

A new Ni-Fe-based superalloy, HT-X, has been developed for applications in 700 °C advanced ultra-supercritical (A-USC) boilers. The HT-X alloy is subjected to various heat treatments. Tensile tests are conducted at room temperature (RT), 700 °C and 750 °C. Creep tests are carried out under conditions of 700 °C/300 MPa and 750 °C/150 MPa. After aging treatment, the yield strength of the HT-X alloy at RT and 750 °C is 787 MPa and 624 MPa, respectively. When additional thermal exposure at 750 °C for 5400 h is applied, the yield strength is decreased to 656 MPa at RT and 480 MPa at 700 °C. For an aged specimen, the a/2<110>dislocation shearing process occurs when tensile testing is conducted at RT and 750 °C. As the γ' precipitate size increases in the specimen that is thermally exposed at 750 °C for 5400 h, Orowan bowing is the dominant dislocation process, and stacking faults develop in the γ' precipitates at both RT and 700 °C. Dislocation slip combined with climb is the dominant mechanism under the creep testing conditions. The factors that affect the mechanical properties and deformation mechanisms are discussed.

25 CFR 700.529 - Negotiations for employment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Negotiations for employment. 700.529 Section 700.529 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.529 Negotiations for employment. An employee shall inform the...

25 CFR 700.529 - Negotiations for employment.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Negotiations for employment. 700.529 Section 700.529 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.529 Negotiations for employment. An employee shall inform the...

25 CFR 700.529 - Negotiations for employment.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Negotiations for employment. 700.529 Section 700.529 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.529 Negotiations for employment. An employee shall inform the...

25 CFR 700.529 - Negotiations for employment.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Negotiations for employment. 700.529 Section 700.529 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.529 Negotiations for employment. An employee shall inform the...

25 CFR 700.529 - Negotiations for employment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Negotiations for employment. 700.529 Section 700.529 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.529 Negotiations for employment. An employee shall inform the...

25 CFR 700.133 - Notice of displacement.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Notice of displacement. 700.133 Section 700.133 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Relocation Requirements § 700.133 Notice of displacement. After the Commission's Relocation Report...

25 CFR 700.133 - Notice of displacement.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Notice of displacement. 700.133 Section 700.133 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Relocation Requirements § 700.133 Notice of displacement. After the Commission's Relocation Report...

25 CFR 700.133 - Notice of displacement.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Notice of displacement. 700.133 Section 700.133 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Relocation Requirements § 700.133 Notice of displacement. After the Commission's Relocation Report...

25 CFR 700.133 - Notice of displacement.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Notice of displacement. 700.133 Section 700.133 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Relocation Requirements § 700.133 Notice of displacement. After the Commission's Relocation Report...

25 CFR 700.133 - Notice of displacement.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Notice of displacement. 700.133 Section 700.133 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Relocation Requirements § 700.133 Notice of displacement. After the Commission's Relocation Report...

28 CFR 700.19 - Preservation of records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Preservation of records. 700.19 Section 700.19 Judicial Administration OFFICE OF INDEPENDENT COUNSEL PRODUCTION OR DISCLOSURE OF MATERIAL OR... the Privacy Act of 1974 § 700.19 Preservation of records. The Office shall preserve all correspondence...

32 CFR 700.804 - Organization of commands.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Organization of commands. 700.804 Section 700... REGULATIONS AND OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.804 Organization of commands. All commands and other activities of the...

32 CFR 700.804 - Organization of commands.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Organization of commands. 700.804 Section 700... REGULATIONS AND OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.804 Organization of commands. All commands and other activities of the...

32 CFR 700.804 - Organization of commands.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Organization of commands. 700.804 Section 700... REGULATIONS AND OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.804 Organization of commands. All commands and other activities of the...

32 CFR 700.804 - Organization of commands.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Organization of commands. 700.804 Section 700... REGULATIONS AND OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.804 Organization of commands. All commands and other activities of the...

32 CFR 700.804 - Organization of commands.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Organization of commands. 700.804 Section 700... REGULATIONS AND OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Commanding Officer Commanding Officers in General § 700.804 Organization of commands. All commands and other activities of the...

40 CFR 700.41 - Radon user fees.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Radon user fees. 700.41 Section 700.41 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT GENERAL Fees § 700.41 Radon user fees. User fees relating to radon proficiency programs authorized under the...

40 CFR 700.41 - Radon user fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Radon user fees. 700.41 Section 700.41 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT GENERAL Fees § 700.41 Radon user fees. User fees relating to radon proficiency programs authorized under the...

7 CFR 1944.700 - OMB control number.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 13 2014-01-01 2013-01-01 true OMB control number. 1944.700 Section 1944.700...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.700 OMB control number... to a collection of information unless it displays a valid OMB control number. The valid OMB control...

7 CFR 1944.700 - OMB control number.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 13 2013-01-01 2013-01-01 false OMB control number. 1944.700 Section 1944.700...) PROGRAM REGULATIONS (CONTINUED) HOUSING Housing Preservation Grants § 1944.700 OMB control number... to a collection of information unless it displays a valid OMB control number. The valid OMB control...

25 CFR 700.81 - Monthly housing cost.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Monthly housing cost. 700.81 Section 700.81 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.81 Monthly housing cost. (a) General. The term monthly housing...

ICC 700-2012: 2012 National Green Building Standard (ICC 700)

EPA Pesticide Factsheets

Description of the ICC 700-2012: 2012 National Green Building Standard, a rating and certification system that aims to encourage increased environmental and health performance in residences and residential portions of buildings.

32 CFR 700.1020 - Exercise of authority.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Exercise of authority. 700.1020 Section 700.1020... Command Authority § 700.1020 Exercise of authority. (a) All persons in the naval service on active service..., suspended from duty, in confinement or otherwise incapable of discharging their duties, exercise authority...

32 CFR 700.1020 - Exercise of authority.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Exercise of authority. 700.1020 Section 700.1020... Command Authority § 700.1020 Exercise of authority. (a) All persons in the naval service on active service..., suspended from duty, in confinement or otherwise incapable of discharging their duties, exercise authority...

32 CFR 700.1020 - Exercise of authority.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Exercise of authority. 700.1020 Section 700.1020... Command Authority § 700.1020 Exercise of authority. (a) All persons in the naval service on active service..., suspended from duty, in confinement or otherwise incapable of discharging their duties, exercise authority...

32 CFR 700.1020 - Exercise of authority.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Exercise of authority. 700.1020 Section 700.1020... Command Authority § 700.1020 Exercise of authority. (a) All persons in the naval service on active service..., suspended from duty, in confinement or otherwise incapable of discharging their duties, exercise authority...

32 CFR 700.304 - Recommendations to Congress.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Recommendations to Congress. 700.304 Section 700... The Secretary of the Navy § 700.304 Recommendations to Congress. After first informing the Secretary of Defense, the Secretary of the Navy may make such recommendations to Congress relating to the...

32 CFR 700.304 - Recommendations to Congress.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Recommendations to Congress. 700.304 Section 700... The Secretary of the Navy § 700.304 Recommendations to Congress. After first informing the Secretary of Defense, the Secretary of the Navy may make such recommendations to Congress relating to the...

32 CFR 700.1020 - Exercise of authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Exercise of authority. 700.1020 Section 700.1020... Command Authority § 700.1020 Exercise of authority. (a) All persons in the naval service on active service..., suspended from duty, in confinement or otherwise incapable of discharging their duties, exercise authority...

25 CFR 700.515 - Conflicts of interest.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Conflicts of interest. 700.515 Section 700.515 Indians... Employee Responsibility and Conduct § 700.515 Conflicts of interest. (a) A conflict of interest may exist... or herself, close friends, relatives, or business associates. A conflict of interest may also exist...

14 CFR § 1212.700 - NASA employees.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false NASA employees. § 1212.700 Section § 1212.700 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS NASA Authority and Responsibilities § 1212.700 NASA employees. (a) Each NASA employee is responsible...

25 CFR 700.61 - Fair market value.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Fair market value. 700.61 Section 700.61 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.61 Fair market value. Fair market value shall mean the value...

25 CFR 700.315 - Post-hearing briefs.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days after...

25 CFR 700.315 - Post-hearing briefs.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days after...

25 CFR 700.315 - Post-hearing briefs.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days after...

25 CFR 700.315 - Post-hearing briefs.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days after...

25 CFR 700.315 - Post-hearing briefs.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Post-hearing briefs. 700.315 Section 700.315 Indians THE... of Eligibility, Hearing and Administrative Review (Appeals) § 700.315 Post-hearing briefs. Applicants may submit post-hearing briefs or written comments to the Presiding Officer within fourteen days after...

32 CFR 700.330 - The Staff Assistants.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false The Staff Assistants. 700.330 Section 700.330 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Office of the Secretary of the Navy/the Staff Assistants § 700.330 The Staff Assistants. The Staff...

32 CFR 700.330 - The Staff Assistants.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false The Staff Assistants. 700.330 Section 700.330 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Office of the Secretary of the Navy/the Staff Assistants § 700.330 The Staff Assistants. The Staff...

32 CFR 700.330 - The Staff Assistants.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false The Staff Assistants. 700.330 Section 700.330 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Office of the Secretary of the Navy/the Staff Assistants § 700.330 The Staff Assistants. The Staff...

32 CFR 700.330 - The Staff Assistants.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false The Staff Assistants. 700.330 Section 700.330 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Office of the Secretary of the Navy/the Staff Assistants § 700.330 The Staff Assistants. The Staff...

32 CFR 700.330 - The Staff Assistants.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false The Staff Assistants. 700.330 Section 700.330 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... Office of the Secretary of the Navy/the Staff Assistants § 700.330 The Staff Assistants. The Staff...

21 CFR 700.11 - Cosmetics containing bithionol.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Cosmetics containing bithionol. 700.11 Section 700...) COSMETICS GENERAL Requirements for Specific Cosmetic Products § 700.11 Cosmetics containing bithionol. (a) Bithionol has been used to some extent as an antibacterial agent in cosmetic preparations such as detergent...

21 CFR 700.11 - Cosmetics containing bithionol.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Cosmetics containing bithionol. 700.11 Section 700...) COSMETICS GENERAL Requirements for Specific Cosmetic Products § 700.11 Cosmetics containing bithionol. (a) Bithionol has been used to some extent as an antibacterial agent in cosmetic preparations such as detergent...

21 CFR 700.11 - Cosmetics containing bithionol.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Cosmetics containing bithionol. 700.11 Section 700...) COSMETICS GENERAL Requirements for Specific Cosmetic Products § 700.11 Cosmetics containing bithionol. (a) Bithionol has been used to some extent as an antibacterial agent in cosmetic preparations such as detergent...

21 CFR 700.11 - Cosmetics containing bithionol.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Cosmetics containing bithionol. 700.11 Section 700...) COSMETICS GENERAL Requirements for Specific Cosmetic Products § 700.11 Cosmetics containing bithionol. (a) Bithionol has been used to some extent as an antibacterial agent in cosmetic preparations such as detergent...

21 CFR 700.11 - Cosmetics containing bithionol.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Cosmetics containing bithionol. 700.11 Section 700...) COSMETICS GENERAL Requirements for Specific Cosmetic Products § 700.11 Cosmetics containing bithionol. (a) Bithionol has been used to some extent as an antibacterial agent in cosmetic preparations such as detergent...

KPU-300, a Novel Benzophenone–Diketopiperazine–Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M Phase

PubMed Central

Okuyama, Kohei; Kaida, Atsushi; Hayashi, Yoshiki; Hayashi, Yoshio; Harada, Kiyoshi; Miura, Masahiko

2015-01-01

KPU-300 is a novel colchicine-type anti-microtubule agent derived from plinabulin (NPI-2358). We characterized the effects of KPU-300 on cell cycle kinetics and radiosensitization using HeLa cells expressing the fluorescent ubiquitination-based cell cycle indicator (Fucci). Cells treated with 30 nM KPU-300 for 24 h were efficiently synchronized in M phase and contained clearly detectable abnormal Fucci fluorescence. Two-dimensional flow-cytometric analysis revealed a fraction of cells distinct from the normal Fucci fluorescence pattern. Most of these cells were positive for an M phase marker, the phosphorylated form of histone H3. Cells growing in spheroids responded similarly to the drug, and the inner quiescent fraction also responded after recruitment to the growth fraction. When such drug-treated cells were irradiated in monolayer, a remarkable radiosensitization was observed. To determine whether this radiosensitization was truly due to the synchronization in M phase, we compared the radiosensitivity of cells synchronized by KPU-300 treatment and cells in early M phase isolated by a combined method that took advantage of shake-off and the properties of the Fucci system. Following normalization against the surviving fraction of cells treated with KPU-300 alone, the surviving fractions of cells irradiated in early M phase coincided. Taken together with potential vascular disrupting function in vivo, we propose a novel radiosensitizing strategy using KPU-300. PMID:26716455

KPU-300, a Novel Benzophenone-Diketopiperazine-Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M Phase.

PubMed

Okuyama, Kohei; Kaida, Atsushi; Hayashi, Yoshiki; Hayashi, Yoshio; Harada, Kiyoshi; Miura, Masahiko

2015-01-01

KPU-300 is a novel colchicine-type anti-microtubule agent derived from plinabulin (NPI-2358). We characterized the effects of KPU-300 on cell cycle kinetics and radiosensitization using HeLa cells expressing the fluorescent ubiquitination-based cell cycle indicator (Fucci). Cells treated with 30 nM KPU-300 for 24 h were efficiently synchronized in M phase and contained clearly detectable abnormal Fucci fluorescence. Two-dimensional flow-cytometric analysis revealed a fraction of cells distinct from the normal Fucci fluorescence pattern. Most of these cells were positive for an M phase marker, the phosphorylated form of histone H3. Cells growing in spheroids responded similarly to the drug, and the inner quiescent fraction also responded after recruitment to the growth fraction. When such drug-treated cells were irradiated in monolayer, a remarkable radiosensitization was observed. To determine whether this radiosensitization was truly due to the synchronization in M phase, we compared the radiosensitivity of cells synchronized by KPU-300 treatment and cells in early M phase isolated by a combined method that took advantage of shake-off and the properties of the Fucci system. Following normalization against the surviving fraction of cells treated with KPU-300 alone, the surviving fractions of cells irradiated in early M phase coincided. Taken together with potential vascular disrupting function in vivo, we propose a novel radiosensitizing strategy using KPU-300.

Statistical model based iterative reconstruction in clinical CT systems. Part III. Task-based kV/mAs optimization for radiation dose reduction

PubMed Central

Li, Ke; Gomez-Cardona, Daniel; Hsieh, Jiang; Lubner, Meghan G.; Pickhardt, Perry J.; Chen, Guang-Hong

2015-01-01

Purpose: For a given imaging task and patient size, the optimal selection of x-ray tube potential (kV) and tube current-rotation time product (mAs) is pivotal in achieving the maximal radiation dose reduction while maintaining the needed diagnostic performance. Although contrast-to-noise (CNR)-based strategies can be used to optimize kV/mAs for computed tomography (CT) imaging systems employing the linear filtered backprojection (FBP) reconstruction method, a more general framework needs to be developed for systems using the nonlinear statistical model-based iterative reconstruction (MBIR) method. The purpose of this paper is to present such a unified framework for the optimization of kV/mAs selection for both FBP- and MBIR-based CT systems. Methods: The optimal selection of kV and mAs was formulated as a constrained optimization problem to minimize the objective function, Dose(kV,mAs), under the constraint that the achievable detectability index d′(kV,mAs) is not lower than the prescribed value of d℞′ for a given imaging task. Since it is difficult to analytically model the dependence of d′ on kV and mAs for the highly nonlinear MBIR method, this constrained optimization problem is solved with comprehensive measurements of Dose(kV,mAs) and d′(kV,mAs) at a variety of kV–mAs combinations, after which the overlay of the dose contours and d′ contours is used to graphically determine the optimal kV–mAs combination to achieve the lowest dose while maintaining the needed detectability for the given imaging task. As an example, d′ for a 17 mm hypoattenuating liver lesion detection task was experimentally measured with an anthropomorphic abdominal phantom at four tube potentials (80, 100, 120, and 140 kV) and fifteen mA levels (25 and 50–700) with a sampling interval of 50 mA at a fixed rotation time of 0.5 s, which corresponded to a dose (CTDIvol) range of [0.6, 70] mGy. Using the proposed method, the optimal kV and mA that minimized dose for the

Comparison of two text message (mHealth) campaigns for the Deaf: Contracted out v. conducted in-house.

PubMed

Hacking, Damian; Lau, Yan Kwan; Haricharan, Hanne Jensen; Heap, Marion

2015-11-20

Cell phone-based health information (mobile health or mHealth) campaigns are an emerging technology. This evaluation focused on the aspect of cost of two health information campaigns, one on hypertension and one on pregnancy. Researchers could either contract out the technical components of the campaigns or attempt to run the campaigns themselves, in-house. The in-house campaigns cost an estimated ZAR13 548.72 v. the private provider quotes which ranged from ZAR27 542.97 to ZAR34 227.59. Running the campaigns in-house was more labour intensive and required more technical expertise, but had a reduced delivery failure rate (9.2% in-house v. 30.0% private provider). Running small to medium SMS (text message) campaigns for evaluative purposes proved advantageous over contracting out to private providers. Larger-scale evaluations and full-scale roll-out will require the services of private providers, but it is still essential that researchers actively engage with and monitor the technical aspects of these campaigns.

Effects of S(+)-efonidipine on the rabbit sinus node action potential and calcium channel subunits Ca(V)1.2, Ca(V)1.3 and Ca(V)3.1.

PubMed

Tanaka, Hikaru; Namekata, Iyuki; Ogawa, Toru; Tsuneoka, Yayoi; Komikado, Chisa; Takahara, Akira; Iida-Tanaka, Naoko; Izumi-Nakaseko, Hiroko; Tsuru, Hiromichi; Adachi-Akahane, Satomi

2010-12-15

The effect of S(+)-efonidipine on sinus node action potential and calcium channel α-subunits was examined. The slope of the phase 4 depolarization of isolated rabbit sinus node tissue was significantly reduced by S(+)-efonidipine (1 μM), slightly reduced by nifedipine (1 μM), but was not affected by R(-)-efonidipine. S(+)-efonidipine (1 μM), inhibited the expressed Ca(V)1.2, Ca(V)1.3 and Ca(V)3.1 channel currents by 75.7%, 75.3% and 94.0%, nifedipine 84.0%, 43.2% and 14.9%, and R(-)-efonidipine 30.0%, 19.6% and 92.8%, respectively. Thus, the prolongation of the phase 4 depolarization of the rabbit sinus node by S(+)-efonidipine may be explained by blockade of the Ca(V)1.3 channel current. Copyright © 2010 Elsevier B.V. All rights reserved.

30 CFR 937.700 - Oregon Federal program.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Oregon Federal program. 937.700 Section 937.700... PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE OREGON § 937.700 Oregon Federal program. (a) This part contains all rules that are applicable to surface coal mining operations in Oregon...

30 CFR 937.700 - Oregon Federal program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Oregon Federal program. 937.700 Section 937.700... PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE OREGON § 937.700 Oregon Federal program. (a) This part contains all rules that are applicable to surface coal mining operations in Oregon...

30 CFR 937.700 - Oregon Federal program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Oregon Federal program. 937.700 Section 937.700... PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE OREGON § 937.700 Oregon Federal program. (a) This part contains all rules that are applicable to surface coal mining operations in Oregon...

16 CFR 700.2 - Date of manufacture.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Date of manufacture. 700.2 Section 700.2... MAGNUSON-MOSS WARRANTY ACT INTERPRETATIONS OF MAGNUSON-MOSS WARRANTY ACT § 700.2 Date of manufacture... after July 4, 1975. When a consumer purchases repair of a consumer product the date of manufacture of...

32 CFR 700.337 - The Auditor General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false The Auditor General. 700.337 Section 700.337... Office of the Secretary of the Navy/the Staff Assistants § 700.337 The Auditor General. (a) The Auditor... Government auditing standards. (b) The Auditor General can provide information and may provide assistance and...

25 CFR 700.343 - Life estate leases.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Life estate leases. 700.343 Section 700.343 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Life Estate Leases § 700.343 Life estate leases. The Commission shall execute a life estate lease to each applicant...

25 CFR 700.343 - Life estate leases.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Life estate leases. 700.343 Section 700.343 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Life Estate Leases § 700.343 Life estate leases. The Commission shall execute a life estate lease to each applicant...

32 CFR 700.923 - Precautions for health.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Precautions for health. 700.923 Section 700.923... Contents § 700.923 Precautions for health. The senior officer present shall take precautions to preserve the health of the persons under his or her authority. He or she shall obtain information regarding the...

32 CFR 700.923 - Precautions for health.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Precautions for health. 700.923 Section 700.923... Contents § 700.923 Precautions for health. The senior officer present shall take precautions to preserve the health of the persons under his or her authority. He or she shall obtain information regarding the...

32 CFR 700.923 - Precautions for health.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Precautions for health. 700.923 Section 700.923... Contents § 700.923 Precautions for health. The senior officer present shall take precautions to preserve the health of the persons under his or her authority. He or she shall obtain information regarding the...

32 CFR 700.923 - Precautions for health.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Precautions for health. 700.923 Section 700.923... Contents § 700.923 Precautions for health. The senior officer present shall take precautions to preserve the health of the persons under his or her authority. He or she shall obtain information regarding the...

32 CFR 700.337 - The Auditor General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false The Auditor General. 700.337 Section 700.337... Office of the Secretary of the Navy/the Staff Assistants § 700.337 The Auditor General. (a) The Auditor... Government auditing standards. (b) The Auditor General can provide information and may provide assistance and...

25 CFR 700.343 - Life estate leases.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Life estate leases. 700.343 Section 700.343 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Life Estate Leases § 700.343 Life estate leases. The Commission shall execute a life estate lease to each applicant...

25 CFR 700.343 - Life estate leases.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Life estate leases. 700.343 Section 700.343 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Life Estate Leases § 700.343 Life estate leases. The Commission shall execute a life estate lease to each applicant...

25 CFR 700.343 - Life estate leases.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Life estate leases. 700.343 Section 700.343 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Life Estate Leases § 700.343 Life estate leases. The Commission shall execute a life estate lease to each applicant...

25 CFR 700.269 - Accounting for disclosures.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Accounting for disclosures. 700.269 Section 700.269... Privacy Act § 700.269 Accounting for disclosures. (a) Maintenance of an accounting. (1) Where a record is...), an accounting shall be made. (2) The accounting shall record (i) the date, nature, and purpose of...

M-H characteristics and demagnetization resistance of samarium-cobalt permanent magnets to 300 C

NASA Technical Reports Server (NTRS)

Niedra, J. M.

1992-01-01

The influence of temperature on the M-H demagnetization characteristics of permanent magnets is important information for the full utilization of the capabilities of samarium-cobalt magnets at high temperatures in demagnetization-resistant permanent magnet devices. In high temperature space power converters, such as free-piston Stirling engine driven linear alternators, magnet demagnetization can occur as long-term consequence of thermal agitation of domains and of metallurgical change, and also as an immediate consequence of too large an applied field. Investigated here is the short-term demagnetization resistance to applied fields derived from basic M-H data. These quasistatic demagnetization data were obtained for commercial, high-intrinsic-coercivity, Sm2Co17-type magnets from 5 sources, in the temperature range 23 to 300 C. An electromagnet driven, electronic hysteresigraph was used to test the 1-cm cubic samples. The observed variation of the 2nd quadrant M-H characteristics was a typical rapid loss of M-coercivity and a relatively lesser loss of remanence with increasing temperature.

25 CFR 161.700 - What is trespass?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false What is trespass? 161.700 Section 161.700 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER NAVAJO PARTITIONED LANDS GRAZING PERMITS Trespass § 161.700 What is trespass? Under this part, trespass is any unauthorized use of, or action on...

25 CFR 161.700 - What is trespass?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true What is trespass? 161.700 Section 161.700 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER NAVAJO PARTITIONED LANDS GRAZING PERMITS Trespass § 161.700 What is trespass? Under this part, trespass is any unauthorized use of, or action on...

25 CFR 161.700 - What is trespass?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false What is trespass? 161.700 Section 161.700 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER NAVAJO PARTITIONED LANDS GRAZING PERMITS Trespass § 161.700 What is trespass? Under this part, trespass is any unauthorized use of, or action on...

25 CFR 161.700 - What is trespass?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is trespass? 161.700 Section 161.700 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER NAVAJO PARTITIONED LANDS GRAZING PERMITS Trespass § 161.700 What is trespass? Under this part, trespass is any unauthorized use of, or action on...

25 CFR 161.700 - What is trespass?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false What is trespass? 161.700 Section 161.700 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER NAVAJO PARTITIONED LANDS GRAZING PERMITS Trespass § 161.700 What is trespass? Under this part, trespass is any unauthorized use of, or action on...

25 CFR 700.721 - Range management plans.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Range management plans. 700.721 Section 700.721 Indians... Lands Grazing § 700.721 Range management plans. The Commissioner (or his designee) and the permittees of each range unit will meet as a group and develop a Range Management Plan for the common use of the...

Electron impact excitation of the low-lying 3s[3/2]{sub 1} and 3s{sup ′}[1/2]{sub 1} levels in neon for incident energies between 20 and 300 eV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoshino, M., E-mail: masami-h@sophia.ac.jp; Murai, H.; Kato, H.

2013-11-14

Absolute differential cross sections (DCSs) for electron impact of the two lower-lying 3s[3/2]{sub 1} ({sup 3}P{sub 0}) and 3s{sup ′}[1/2]{sub 1} ({sup 1}P{sub 1}) electronic states in neon (Ne) have been determined for eight incident electron energies in the range 20–300 eV. Comparisons between our results and previous measurements and calculations, where possible, are provided with best agreement being found with the recent large-scale B-spline R-matrix computations [O. Zatsarinny and K. Bartschat, Phys. Rev. A 86, 022717 (2012)]. Based on these DCSs at 100, 200, and 300 eV, a generalised oscillator strength analysis enabled us to determine estimates for themore » optical oscillator strengths of the 3s[3/2]{sub 1} and 3s{sup ′}[1/2]{sub 1} levels. In this case, excellent agreement was found with a range of independent experiments and calculations, giving us some confidence in the validity of our measurement and analysis procedures. Integral cross sections, derived from the present DCSs, were presented graphically and discussed elsewhere [M. Hoshino, H. Murai, H. Kato, Y. Itikawa, M. J. Brunger, and H. Tanaka, Chem. Phys. Lett. 585, 33 (2013)], but are tabulated here for completeness.« less

Isotope Separation in Concurrent Gas Centrifuges

NASA Astrophysics Data System (ADS)

Bogovalov, S. V.; Borman, V. D.

An analytical equation defining separative power of an optimized concurrent gas centrifuge is obtained for an arbitrary binary mixture of isotopes. In the case of the uranium isotopes the equation gives δU= 12.7(V/700 m/s)2(300 K/T)L, kg SWU/yr, where L and V are the length and linear velocity of the rotor of the gas centrifuge, T is the temperature. This formula well agrees with an empirical separative power of counter current gas centrifuges.

Synthesis and electrochemical properties of Li2/3Ni1/3Mn2/3O2 as a novel 5 V class positive electrode material for lithium-ion batteries

NASA Astrophysics Data System (ADS)

Chiba, Kazuki; Shikano, Masahiro; Sakaebe, Hikari

2016-02-01

A lithium nickel manganese oxide, O3-Li2/3Ni1/3Mn2/3O2, is synthesized from the precursor, P3-Na2/3Ni1/3Mn2/3O2, by a Na+/Li+ ion exchange reaction using molten salt. Post-heating at 300, 400, 500, 600, and 700 °C is carried out for 5 h in air. The products are characterized by powder XRD, inductively coupled plasma-atomic emission spectroscopy (ICP-AES), SEM, 6Li-magic-angle-spinning-NMR, and electrochemical measurements. The charge/discharge profiles of O3-Li2/3Ni1/3Mn2/3O2, thermally treated at 500 °C, show a high-potential plateau region at 4.8 V. Furthermore, sloping voltage profiles are observed at an average voltage of 3.21 V. An initial discharge capacity of 257 mA h g-1 is obtained between 2.0 and 4.8 V with a current density of 15 mA g-1 at 25 °C. This capacity corresponds to 0.90 electron transfers per formula unit. This study shows that Post-heating of O3-Li2/3Ni1/3Mn2/3O2 is effective to improve its electrochemical properties.

Sub-second variations of high energy ( 300 keV) hard X-ray emission from solar flares

NASA Technical Reports Server (NTRS)

Bai, Taeil

1986-01-01

Subsecond variations of hard X-ray emission from solar flares were first observed with a balloon-borne detector. With the launch of the Solar Maximum Mission (SMM), it is now well known that subsecond variations of hard X-ray emission occur quite frequently. Such rapid variations give constraints on the modeling of electron energization. Such rapid variations reported until now, however, were observed at relatively low energies. Fast mode data obtained by the Hard X-ray Burst Spectrometer (HXRBS) has time resolution of approximately 1 ms but has no energy resolution. Therefore, rapid fluctuations observed in the fast-mode HXRBS data are dominated by the low energy hard X-rays. It is of interest to know whether rapid fluctuations are observed in high-energy X-rays. The highest energy band at which subsecond variations were observed is 223 to 1057 keV. Subsecond variations observed with HXRBS at energies greater than 300 keV are reported, and the implications discussed.

HTLV-I Tax transrepresses the human c-Myb promoter independently of its interaction with CBP or p300.

PubMed

Nicot, C; Mahieux, R; Opavsky, R; Cereseto, A; Wolff, L; Brady, J N; Franchini, G

2000-04-20

The c-Myb proto-oncogene is preferentially expressed in hematopoietic lineages, and highly expressed in several leukemia types. The Human T-cell Leukemia Virus Type I (HTLV-I) is the etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL). A previous report suggested that Tax, the viral transactivator, is able to suppress the transactivation potential of c-Myb protein by competing for recruitment of CBP. We tested whether such a competition could affect transcription from the c-Myb promoter in Tax expressing T-cells. Using several c-Myb promoter reporter constructs carrying mutations in various regions, we demonstrate that Tax suppression of c-Myb transactivation results in transrepression of the c-Myb promoter through the Myb responsive elements in Jurkat T-cells. The ability of Tax mutants M22, M47 and V89A to interact with the full-length CBP and p300 proteins in vitro, and their ability to repress the c-Myb promoter, was then evaluated. Although both M47 and M22 bind to CBP and p300 to a similar extent, only M47 was able to repress the c-Myb promoter, suggesting that competition for CBP/p300 binding was not the mechanism underlying Tax's effect. This concept was further supported by the fact that the Tax mutant V89A transrepresses the c-Myb promoter efficiently in spite of an impaired binding to CBP and p300. Therefore, Tax-mediated repression of the c-Myb promoter appears to be independent from a direct competition between c-Myb and Tax for recruitment of CBP/p300. Interestingly, a decreased transcription from the endogenous c-Myb promoter was observed in several HTLV-I transformed T-cell lines. Finally, the ability of Tax to directly repress the endogenous c-Myb promoter was demonstrated in a Jurkat cell line stably transfected with a tax gene driven by a cadmium-inducible promoter.

15 CFR 700.60 - General provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false General provisions. 700.60 Section 700.60 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS...

15 CFR 700.61 - Rating Authorizations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Rating Authorizations. 700.61 Section 700.61 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS...

15 CFR 700.70 - General provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false General provisions. 700.70 Section 700.70 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS...

32 CFR 700.1167 - Supremacist activity.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Supremacist activity. 700.1167 Section 700.1167 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... organizations when such activities are detrimental to good order, discipline, or mission accomplishment. ...

32 CFR 700.1167 - Supremacist activity.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Supremacist activity. 700.1167 Section 700.1167 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... organizations when such activities are detrimental to good order, discipline, or mission accomplishment. ...

32 CFR 700.1167 - Supremacist activity.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Supremacist activity. 700.1167 Section 700.1167 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... organizations when such activities are detrimental to good order, discipline, or mission accomplishment. ...

32 CFR 700.1167 - Supremacist activity.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Supremacist activity. 700.1167 Section 700.1167 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... organizations when such activities are detrimental to good order, discipline, or mission accomplishment. ...

32 CFR 700.1167 - Supremacist activity.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Supremacist activity. 700.1167 Section 700.1167 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS... organizations when such activities are detrimental to good order, discipline, or mission accomplishment. ...

40 CFR 272.700 - State authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 272.700 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois § 272.700 State authorization. (a) The State of Illinois is authorized to administer and enforce a hazardous waste management program in lieu of the...

Ninth Annual V. M. Goldschmidt Conference

NASA Technical Reports Server (NTRS)

1999-01-01

This volume contains abstracts that have been accepted for presentation at the Ninth Annual V. M. Goldschmidt Conference, August 22-27, 1999, hosted by the Department of Earth and Planetary Sciences, Harvard University, Cambridge, Massachusetts. The meeting is a forum for presenting and discussing new chemical and isotopic measurements, experimental and theoretical results, and discoveries in geochemistry and cosmochemistry.

Two-phase flow in short horizontal rectangular microchannels with a height of 300 μm

NASA Astrophysics Data System (ADS)

Chinnov, E. A.; Ron'shin, F. V.; Kabov, O. A.

2015-09-01

The two-phase flow in a narrow short horizontal channel with a rectangular cross section is studied experimentally. The channel has a width of 10, 20, or 30 mm and a height of 300 μm. The specifics of formation of such two-phase flows are investigated. It is demonstrated that the regions of bubble and churn flow regimes grow and constrain the region of jet flow as the channel gets wider. The boundaries of the regions of annular and stratified flow regimes remain almost unaltered.

34 CFR 300.521-300.529 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true [Reserved] 300.521-300.529 Section 300.521-300.529... CHILDREN WITH DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§ 300.521-300.529 [Reserved] Discipline Procedures ...

34 CFR 300.521-300.529 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false [Reserved] 300.521-300.529 Section 300.521-300.529... CHILDREN WITH DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§ 300.521-300.529 [Reserved] Discipline Procedures ...

34 CFR 300.521-300.529 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true [Reserved] 300.521-300.529 Section 300.521-300.529... CHILDREN WITH DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§ 300.521-300.529 [Reserved] Discipline Procedures ...

34 CFR 300.521-300.529 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false [Reserved] 300.521-300.529 Section 300.521-300.529... CHILDREN WITH DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§ 300.521-300.529 [Reserved] Discipline Procedures ...

34 CFR 300.521-300.529 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false [Reserved] 300.521-300.529 Section 300.521-300.529... CHILDREN WITH DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children §§ 300.521-300.529 [Reserved] Discipline Procedures ...

7Li(p,n)7Be and 12C(p,n)12N reactions at 200, 300, and 400 MeV

NASA Astrophysics Data System (ADS)

Watson, J. W.; Pourang, R.; Abegg, R.; Alford, W. P.; Celler, A.; El-Kateb, S.; Frekers, D.; Häusser, O.; Helmer, R.; Henderson, R.; Hicks, K.; Jackson, K. P.; Jeppesen, R. G.; Miller, C. A.; Vetterli, M.; Yen, S.; Zafiratos, C. D.

1989-07-01

At 200, 300, and 400 MeV bombarding energies, we measured cross section angular distributions for the 7Li(p,n)7Be(g.s.+0.43 MeV) reaction and 0° cross sections for the 12C(p,n)12N(g.s.) reaction. Systematics of these reactions are presented. The center-of-mass cross section for the 7Li(p,n)7Be(g.s.+0.43 MeV) reaction, when plotted as a function of momentum transfer, is nearly independent of energy. The laboratory cross section for this reaction at 0° in the energy range from 60 to 400 MeV is also independent of energy, having a constant value, to within experimental errors, of 35.5 mb/sr with an estimated uncertainty of +/-1.5 mb/sr.

BPI700-Fc gamma1(700) chimeric gene expression and its protective effect in a mice model of the lethal E. coli infection.

PubMed

Kong, Qing-li; Guan, Yuan-zhi; Jing, Xue-fang; Li, Chen; Guo, Xiang-hua; Lü, Zhe; An, Yun-qing

2006-03-20

Infections caused by gram-negative bacteria (GNB) often lead to high mortality in common clinical settings. The effect of traditional antibiotic therapy is hindered by drug-resistant bacteria and unneutralizable endotoxin. Few effective methods can protect high risk patients from bacterial infection. This study explored the protection of adeno-associated virus 2 (AAV2)-bacteriacidal permeability increasing protein 700 (BPI(700))-fragment crystallizable gamma one 700 (Fc gamma1(700)) chimeric gene transferred mice against the minimal lethal dose (MLD) of E. coli and application of gene therapy for bacterial infection. After AAV2-BPI(700)-Fc gamma1(700) virus transfection, dot blotting and Western blotting were used to detect the target gene products in Chinese hamster ovary-K1 cells (CHO-K1cells). Reverse transcription-polymerase chain reaction and immunohistochemical assay were carried out to show the target gene expression in mice. Modified BPI-enzyme linked immunosorbent assay was used to identify the target gene products in murine serum. The protection of BPI(700)-Fc gamma1(700) gene transferred mice was examined by survival rate after MLD E. coli challenge. Colony forming unit (CFU) count, limulus amebocyte lysate kit and cytokine kit were used to quantify the bacteria, the level of endotoxin, and proinflammatory cytokine. BPI(1-199)-Fc gamma1 protein was identified in the CHO-K1 cell culture supernatant, injected muscles and serum of the gene transferred mice. After MLD E. coli challenge, the survival rate of AAV2-BPI(700)-Fc gamma1(700) gene transferred mice (36.7%) was significantly higher than that of AAV2-enhanced green fluorescent protein (AAV2-EGFP) gene transferred mice (3.3%) and PBS control mice (5.6%). The survival rate of AAV2-BPI(700)-Fc gamma1(700) gene transferred mice treated with cefuroxime sodium was 65.0%. The bacterium number in main viscera, the levels of endotoxin and proinflammatory cytokine (tumor necrosis factor-alpha and interleukin-1

34 CFR 300.538-300.599 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true [Reserved] 300.538-300.599 Section 300.538-300.599 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... Procedures §§ 300.538-300.599 [Reserved] ...

34 CFR 300.538-300.599 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false [Reserved] 300.538-300.599 Section 300.538-300.599 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... Procedures §§ 300.538-300.599 [Reserved] ...

34 CFR 300.538-300.599 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false [Reserved] 300.538-300.599 Section 300.538-300.599 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... Procedures §§ 300.538-300.599 [Reserved] ...

34 CFR 300.538-300.599 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true [Reserved] 300.538-300.599 Section 300.538-300.599 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... Procedures §§ 300.538-300.599 [Reserved] ...

34 CFR 300.538-300.599 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false [Reserved] 300.538-300.599 Section 300.538-300.599 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... Procedures §§ 300.538-300.599 [Reserved] ...

30 CFR 700.10 - Information collection.

Code of Federal Regulations, 2010 CFR

2010-07-01

... longer a surface coal mining and reclamation operation and thereby when regulatory jurisdiction may end... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Information collection. 700.10 Section 700.10 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR GENERAL...

25 CFR 700.523 - Business relationships among employees.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Business relationships among employees. 700.523 Section 700.523 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.523 Business relationships among employees. Business...

25 CFR 700.523 - Business relationships among employees.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Business relationships among employees. 700.523 Section 700.523 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.523 Business relationships among employees. Business...

25 CFR 700.523 - Business relationships among employees.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Business relationships among employees. 700.523 Section 700.523 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.523 Business relationships among employees. Business...

47 CFR 51.700 - Purpose of this subpart.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 47 Telecommunication 3 2013-10-01 2013-10-01 false Purpose of this subpart. 51.700 Section 51.700 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) INTERCONNECTION Reciprocal Compensation for Transport and Termination of Telecommunications Traffic § 51.700 Purpose of this...

Nitrogen-Pressure Shifts in the v3 Band of Methane Measured at Several Temperatures between 300 and 90 K

NASA Technical Reports Server (NTRS)

Tumuhimbise, Anthony T.; Hurtmans, Daniel; Mantz, Arlan W.; Mondelain, Didier

2008-01-01

Remote sensing of the Earth's atmosphere requires accurate knowledge of spectroscopic line parameters for the molecules investigated. Knowledge of the temperature dependence of these parameters is also essential if agreement, at the noise level, between calculated and experimental data is to be achieved. The authors recently published results of nitrogen broadening measurements in the v3 band of 12CH4 using the 5.37 m long absorption path length all-copper Herriott cell. The temperature dependent line parameters determined in the laboratory were applied to fit a portion of the atmospheric spectrum recorded with a balloon-borne remote sensing FTIR instrument, called the Limb Profile Monitor of the Atmosphere, and operating in absorption against the sun. Since the authors had a relatively complete series of data for the P(9) transition in the v3 band of 12CH4, the A2 1 as well as the F2 1, F1 1 and A1 1 lines recorded at different pressures and at four temperatures between 300 and 90 K, we reanalyzed the data to derive pressure shift information at different temperatures. The temperatures for which data were collected and analyzed are 298, 140 and 90K. The high precision pressure shift data obtained here over a large range of temperature demonstrate the ability of our experimental arrangement to address specific questions on a given spectral window like in the balloon experiment or in a satellite project, for example.

III/V nano ridge structures for optical applications on patterned 300 mm silicon substrate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kunert, B.; Guo, W.; Mols, Y.

We report on an integration approach of III/V nano ridges on patterned silicon (Si) wafers by metal organic vapor phase epitaxy (MOVPE). Trenches of different widths (≤500 nm) were processed in a silicon oxide (SiO{sub 2}) layer on top of a 300 mm (001) Si substrate. The MOVPE growth conditions were chosen in a way to guarantee an efficient defect trapping within narrow trenches and to form a box shaped ridge with increased III/V volume when growing out of the trench. Compressively strained InGaAs/GaAs multi-quantum wells with 19% indium were deposited on top of the fully relaxed GaAs ridges as an activemore » material for optical applications. Transmission electron microcopy investigation shows that very flat quantum well (QW) interfaces were realized. A clear defect trapping inside the trenches is observed whereas the ridge material is free of threading dislocations with only a very low density of planar defects. Pronounced QW photoluminescence (PL) is detected from different ridge sizes at room temperature. The potential of these III/V nano ridges for laser integration on Si substrates is emphasized by the achieved ridge volume which could enable wave guidance and by the high crystal quality in line with the distinct PL.« less

15 CFR 700.74 - Violations, penalties, and remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Violations, penalties, and remedies. 700.74 Section 700.74 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade... REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Compliance § 700.74 Violations, penalties, and remedies...

45 CFR 2517.700 - Are matching funds required?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Are matching funds required? 2517.700 Section 2517.700 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE COMMUNITY-BASED SERVICE-LEARNING PROGRAMS Funding Requirements § 2517.700 Are matching...

45 CFR 2519.700 - Are matching funds required?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Are matching funds required? 2519.700 Section 2519.700 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE HIGHER EDUCATION INNOVATIVE PROGRAMS FOR COMMUNITY SERVICE Funding Requirements § 2519.700...

45 CFR 2517.700 - Are matching funds required?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 4 2011-10-01 2011-10-01 false Are matching funds required? 2517.700 Section 2517.700 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE COMMUNITY-BASED SERVICE-LEARNING PROGRAMS Funding Requirements § 2517.700 Are matching...

34 CFR 300.214-300.219 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false [Reserved] 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219 [Reserved] ...

34 CFR 300.158-300.159 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false [Reserved] 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

34 CFR 300.125-300.128 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false [Reserved] 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128...

34 CFR 300.214-300.219 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true [Reserved] 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219 [Reserved] ...

34 CFR 300.214-300.219 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true [Reserved] 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219 [Reserved] ...

34 CFR 300.214-300.219 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false [Reserved] 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219 [Reserved] ...

34 CFR 300.125-300.128 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true [Reserved] 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128...

34 CFR 300.125-300.128 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false [Reserved] 300.125-300.128 Section 300.125-300.128 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.125-300.128...

34 CFR 300.158-300.159 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false [Reserved] 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

34 CFR 300.214-300.219 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false [Reserved] 300.214-300.219 Section 300.214-300.219 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility §§ 300.214-300.219 [Reserved] ...

34 CFR 300.158-300.159 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true [Reserved] 300.158-300.159 Section 300.158-300.159 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES State Eligibility Additional Eligibility Requirements §§ 300.158-300.159...

15 CFR 700.75 - Compliance conflicts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Compliance conflicts. 700.75 Section... DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Compliance § 700.75 Compliance conflicts. If compliance with any... notify the Department of Commerce for resolution of the conflict. [49 FR 30414, July 30, 1984...

31 CFR 700.3 - Recording presence.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Recording presence. 700.3 Section 700.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.3 - Recording presence.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Recording presence. 700.3 Section 700.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.3 - Recording presence.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Recording presence. 700.3 Section 700.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.3 - Recording presence.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Recording presence. 700.3 Section 700.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

31 CFR 700.3 - Recording presence.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Recording presence. 700.3 Section 700.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL LAW ENFORCEMENT TRAINING CENTER, DEPARTMENT OF THE TREASURY REGULATIONS GOVERNING CONDUCT IN OR ON THE FEDERAL LAW...

34 CFR 300.801-300.802 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false [Reserved] 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802 [Reserved] ...

34 CFR 300.801-300.802 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false [Reserved] 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802 [Reserved] ...

34 CFR 300.801-300.802 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true [Reserved] 300.801-300.802 Section 300.801-300.802 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION... CHILDREN WITH DISABILITIES Preschool Grants for Children with Disabilities §§ 300.801-300.802 [Reserved] ...

25 CFR 700.519 - Gifts, entertainment and favors.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Gifts, entertainment and favors. 700.519 Section 700.519... Employee Responsibility and Conduct § 700.519 Gifts, entertainment and favors. (a) Acceptance of gratuities, including gifts, entertainment and favors, (no matter how innocently tendered or received) from those who...

25 CFR 700.519 - Gifts, entertainment and favors.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Gifts, entertainment and favors. 700.519 Section 700.519... Employee Responsibility and Conduct § 700.519 Gifts, entertainment and favors. (a) Acceptance of gratuities, including gifts, entertainment and favors, (no matter how innocently tendered or received) from those who...

25 CFR 700.519 - Gifts, entertainment and favors.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Gifts, entertainment and favors. 700.519 Section 700.519... Employee Responsibility and Conduct § 700.519 Gifts, entertainment and favors. (a) Acceptance of gratuities, including gifts, entertainment and favors, (no matter how innocently tendered or received) from those who...

25 CFR 700.519 - Gifts, entertainment and favors.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Gifts, entertainment and favors. 700.519 Section 700.519... Employee Responsibility and Conduct § 700.519 Gifts, entertainment and favors. (a) Acceptance of gratuities, including gifts, entertainment and favors, (no matter how innocently tendered or received) from those who...

28 CFR 700.14 - Classified information.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Classified information. 700.14 Section... INFORMATION OF THE OFFICE OF INDEPENDENT COUNSEL Protection of Privacy and Access to Individual Records Under the Privacy Act of 1974 § 700.14 Classified information. In processing a request for access to a...

21 CFR 573.700 - Sodium nitrite.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Sodium nitrite. 573.700 Section 573.700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive...

21 CFR 573.700 - Sodium nitrite.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Sodium nitrite. 573.700 Section 573.700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive...

21 CFR 573.700 - Sodium nitrite.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Sodium nitrite. 573.700 Section 573.700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive...

21 CFR 573.700 - Sodium nitrite.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Sodium nitrite. 573.700 Section 573.700 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive...

50 CFR 300.126 - Prohibitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

....130(c). (i) Use or possess in treaty waters a lobster trap or fish trap without a degradable panel, as... § 300.131(b) and (c). (l) Retain on board a berried lobster or strip eggs from or otherwise molest a berried lobster, as specified in § 300.132(a). (m) Possess a lobster smaller than the minimum size, as...

50 CFR 300.126 - Prohibitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

....130(c). (i) Use or possess in treaty waters a lobster trap or fish trap without a degradable panel, as... § 300.131(b) and (c). (l) Retain on board a berried lobster or strip eggs from or otherwise molest a berried lobster, as specified in § 300.132(a). (m) Possess a lobster smaller than the minimum size, as...

25 CFR 700.545 - Alcoholism and drug abuse.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Alcoholism and drug abuse. 700.545 Section 700.545... Employee Responsibility and Conduct § 700.545 Alcoholism and drug abuse. An employee who habitually uses... and drug abuse as serious and treatable illnesses. Excessive absence and poor work performance are two...

25 CFR 700.545 - Alcoholism and drug abuse.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Alcoholism and drug abuse. 700.545 Section 700.545... Employee Responsibility and Conduct § 700.545 Alcoholism and drug abuse. An employee who habitually uses... and drug abuse as serious and treatable illnesses. Excessive absence and poor work performance are two...

25 CFR 700.545 - Alcoholism and drug abuse.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Alcoholism and drug abuse. 700.545 Section 700.545... Employee Responsibility and Conduct § 700.545 Alcoholism and drug abuse. An employee who habitually uses... and drug abuse as serious and treatable illnesses. Excessive absence and poor work performance are two...

25 CFR 700.545 - Alcoholism and drug abuse.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Alcoholism and drug abuse. 700.545 Section 700.545... Employee Responsibility and Conduct § 700.545 Alcoholism and drug abuse. An employee who habitually uses... and drug abuse as serious and treatable illnesses. Excessive absence and poor work performance are two...

32 CFR 700.901 - The senior officer present.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false The senior officer present. 700.901 Section 700... REGULATIONS AND OFFICIAL RECORDS UNITED STATES NAVY REGULATIONS AND OFFICIAL RECORDS The Senior Officer Present Contents § 700.901 The senior officer present. Unless some other officer has been so designated by...

32 CFR 700.312 - Authority over organizational matters.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Authority over organizational matters. 700.312 Section 700.312 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES... of the Navy The Office of the Secretary of the Navy § 700.312 Authority over organizational matters...

32 CFR 700.312 - Authority over organizational matters.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Authority over organizational matters. 700.312 Section 700.312 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES... of the Navy The Office of the Secretary of the Navy § 700.312 Authority over organizational matters...

32 CFR 700.312 - Authority over organizational matters.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Authority over organizational matters. 700.312 Section 700.312 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES... of the Navy The Office of the Secretary of the Navy § 700.312 Authority over organizational matters...

32 CFR 700.312 - Authority over organizational matters.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Authority over organizational matters. 700.312 Section 700.312 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES... of the Navy The Office of the Secretary of the Navy § 700.312 Authority over organizational matters...

32 CFR 700.312 - Authority over organizational matters.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Authority over organizational matters. 700.312 Section 700.312 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES... of the Navy The Office of the Secretary of the Navy § 700.312 Authority over organizational matters...

25 CFR 700.545 - Alcoholism and drug abuse.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Alcoholism and drug abuse. 700.545 Section 700.545... Employee Responsibility and Conduct § 700.545 Alcoholism and drug abuse. An employee who habitually uses... and drug abuse as serious and treatable illnesses. Excessive absence and poor work performance are two...

40 CFR 700.49 - Failure to remit fees.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Failure to remit fees. 700.49 Section 700.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT GENERAL Fees § 700.49 Failure to remit fees. EPA will not consider a section 5 notice to be...

40 CFR 700.49 - Failure to remit fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Failure to remit fees. 700.49 Section 700.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT GENERAL Fees § 700.49 Failure to remit fees. EPA will not consider a section 5 notice to be...

40 CFR 700.49 - Failure to remit fees.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Failure to remit fees. 700.49 Section 700.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT GENERAL Fees § 700.49 Failure to remit fees. EPA will not consider a section 5 notice to be...

40 CFR 700.49 - Failure to remit fees.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Failure to remit fees. 700.49 Section 700.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT GENERAL Fees § 700.49 Failure to remit fees. EPA will not consider a section 5 notice to be...

40 CFR 700.49 - Failure to remit fees.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Failure to remit fees. 700.49 Section 700.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT GENERAL Fees § 700.49 Failure to remit fees. EPA will not consider a section 5 notice to be...

Mechanical Alterations during 800-m Self-Paced Track Running.

PubMed

Girard, Olivier; Millet, Gregoire P; Micallef, Jean-Paul

2017-04-01

We assessed the time course of running mechanical alterations during an 800-m. On a 200-m indoor track, 18 physical education students performed an 800-m self-paced run. Once per lap, ground reaction forces were measured by a 5-m-long force platform system, and used to determine running kinetics/kinematics and spring-mass characteristics. Compared with 100 m (19.4±1.8 km.h -1 ) running velocity progressively decreased at 300, 500 m but levelled-off at 700 m marks (-5.7±4.6, -10.4±8.3, and -9.1±13.5%, respectively; P<0.001). Stride length (-8.5±2.3%, P<0.01) and frequency (-1.0±1.5%, P=0.05) along with peak braking (-7.5±4.4%, P<0.05) and push-off forces (-5.1±7.2%, P<0.05) decreased from 100 m to 700 m. Peak vertical forces (-3.0±2.7%; P>0.05) and leg compression (+2.8±3.9%; P>0.05) remained unchanged, whereas centre of mass vertical displacement (+24.0±7.0%; P<0.001) increased during the run. Vertical stiffness decreased (-18.1±4.4%; P<0.001), whereas leg stiffness was unchanged (-3.2±4.6%; P>0.05). During an 800 m by physical education students, highest running velocity was achieved early during the run, with a progressive decrease in the second half of the trial. While vertical ground force characteristics remained unchanged, non-specialist runners produced lower peak braking and push-off forces, in turn leading to shorter stride length. Spring-mass model characteristics changed toward lower vertical stiffness values, whereas leg stiffness did not change. © Georg Thieme Verlag KG Stuttgart · New York.

JA, a new type of polyunsaturated fatty acid isolated from Juglans mandshurica Maxim, limits the survival and induces apoptosis of heptocarcinoma cells.

PubMed

Gao, Xiu-Li; Lin, Hua; Zhao, Wei; Hou, Ya-Qin; Bao, Yong-Li; Song, Zhen-Bo; Sun, Lu-Guo; Tian, Shang-Yi; Liu, Biao; Li, Yu-Xin

2016-03-01

Juglans mandshurica Maxim (Juglandaceae) is a famous folk medicine for cancer treatment and some natural compounds isolated from it have been studied extensively. Previously we isolated a type of ω-9 polyunsaturated fatty acid (JA) from the bark of J. mandshurica, however little is known about its activity and the underlying mechanisms. In this study, we studied anti-tumor activity of JA on several human cancer cell lines. Results showed that JA is cytotoxic to HepG2, MDA-MB-231, SGC-7901, A549 and Huh7 cells at a concentration exerting minimal toxic effects on L02 cells. The selective toxicity of JA was better than other classical anti-cancer drugs. Further investigation indicated that JA could induce cell apoptosis, characterized by chromatin condensation, DNA fragmentation and activation of the apoptosis-associated proteins such as Caspase-3 and PARP-1. Moreover, we investigated the cellular apoptosis pathway involved in the apoptosis process in HepG2 cells. We found that proteins involved in mitochondrion (cleaved-Caspase-9, Apaf-1, HtrA2/Omi, Bax, and Mitochondrial Bax) and endocytoplasmic reticulum (XBP-1s, GRP78, cleaved-Caspase-7 and cleaved-Caspase-12) apoptotic pathways were up-regulated when cells were treated by JA. In addition, a morphological change in the mitochondrion was detected. Furthermore, we found that JA could inhibit DNA synthesis and induce G2/M cell cycle arrest. The expression of G2-to-M transition related proteins, such as CyclinB1 and phosphorylated-CDK1, were reduced. In contrast, the G2-to-M inhibitor p21 was increased in JA-treated cells. Overall, our results suggest that JA can induce mitochondrion- and endocytoplasmic reticulum-mediated apoptosis, and G2/M phase arrest in HepG2 cells, making it a promising therapeutic agent against hepatoma.

21 CFR 573.700 - Sodium nitrite.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Food Additive... as a preservative and color fixative in canned pet food containing fish, meat, and fish and meat... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sodium nitrite. 573.700 Section 573.700 Food and...

Deconvolution of ferredoxin, plastocyanin, and P700 transmittance changes in intact leaves with a new type of kinetic LED array spectrophotometer.

PubMed

Klughammer, Christof; Schreiber, Ulrich

2016-05-01

A newly developed compact measuring system for assessment of transmittance changes in the near-infrared spectral region is described; it allows deconvolution of redox changes due to ferredoxin (Fd), P700, and plastocyanin (PC) in intact leaves. In addition, it can also simultaneously measure chlorophyll fluorescence. The major opto-electronic components as well as the principles of data acquisition and signal deconvolution are outlined. Four original pulse-modulated dual-wavelength difference signals are measured (785-840 nm, 810-870 nm, 870-970 nm, and 795-970 nm). Deconvolution is based on specific spectral information presented graphically in the form of 'Differential Model Plots' (DMP) of Fd, P700, and PC that are derived empirically from selective changes of these three components under appropriately chosen physiological conditions. Whereas information on maximal changes of Fd is obtained upon illumination after dark-acclimation, maximal changes of P700 and PC can be readily induced by saturating light pulses in the presence of far-red light. Using the information of DMP and maximal changes, the new measuring system enables on-line deconvolution of Fd, P700, and PC. The performance of the new device is demonstrated by some examples of practical applications, including fast measurements of flash relaxation kinetics and of the Fd, P700, and PC changes paralleling the polyphasic fluorescence rise upon application of a 300-ms pulse of saturating light.

32 CFR 700.1052 - Orders to active service.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Orders to active service. 700.1052 Section 700... Command Detail to Duty § 700.1052 Orders to active service. (a) No person who is on leave of absence or not on active service shall be ordered into active service or on duty without permission of the...

32 CFR 700.1052 - Orders to active service.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Orders to active service. 700.1052 Section 700... Command Detail to Duty § 700.1052 Orders to active service. (a) No person who is on leave of absence or not on active service shall be ordered into active service or on duty without permission of the...

32 CFR 700.1052 - Orders to active service.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Orders to active service. 700.1052 Section 700... Command Detail to Duty § 700.1052 Orders to active service. (a) No person who is on leave of absence or not on active service shall be ordered into active service or on duty without permission of the...

32 CFR 700.1052 - Orders to active service.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Orders to active service. 700.1052 Section 700... Command Detail to Duty § 700.1052 Orders to active service. (a) No person who is on leave of absence or not on active service shall be ordered into active service or on duty without permission of the...

32 CFR 700.1052 - Orders to active service.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Orders to active service. 700.1052 Section 700... Command Detail to Duty § 700.1052 Orders to active service. (a) No person who is on leave of absence or not on active service shall be ordered into active service or on duty without permission of the...

32 CFR 700.1056 - Command of a ship.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

32 CFR 700.1058 - Command of a submarine.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Command of a submarine. 700.1058 Section 700... Command Detail to Duty § 700.1058 Command of a submarine. The officer detailed to command a submarine shall be an officer of the line in the Navy, eligible for command at sea and qualified for command of...

32 CFR 700.1058 - Command of a submarine.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Command of a submarine. 700.1058 Section 700... Command Detail to Duty § 700.1058 Command of a submarine. The officer detailed to command a submarine shall be an officer of the line in the Navy, eligible for command at sea and qualified for command of...

32 CFR 700.1058 - Command of a submarine.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Command of a submarine. 700.1058 Section 700... Command Detail to Duty § 700.1058 Command of a submarine. The officer detailed to command a submarine shall be an officer of the line in the Navy, eligible for command at sea and qualified for command of...

32 CFR 700.1058 - Command of a submarine.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Command of a submarine. 700.1058 Section 700... Command Detail to Duty § 700.1058 Command of a submarine. The officer detailed to command a submarine shall be an officer of the line in the Navy, eligible for command at sea and qualified for command of...

32 CFR 700.1058 - Command of a submarine.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Command of a submarine. 700.1058 Section 700... Command Detail to Duty § 700.1058 Command of a submarine. The officer detailed to command a submarine shall be an officer of the line in the Navy, eligible for command at sea and qualified for command of...

32 CFR 700.1056 - Command of a ship.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

32 CFR 700.1056 - Command of a ship.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

32 CFR 700.1056 - Command of a ship.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

32 CFR 700.1056 - Command of a ship.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Command of a ship. 700.1056 Section 700.1056... Command Detail to Duty § 700.1056 Command of a ship. (a) The officer detailed to command a commissioned ship shall be an officer of the line in the Navy eligible for command at sea. (b) The officer detailed...

10 CFR 2.700 - Scope of subpart G.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Scope of subpart G. 2.700 Section 2.700 Energy NUCLEAR... Formal Adjudications § 2.700 Scope of subpart G. The provisions of this subpart apply to and supplement... authorization for high-level radioactive waste repository noticed under §§ 2.101(f)(8) or 2.105(a)(5...

M-wave, H- and V-reflex recruitment curves during maximal voluntary contraction.

PubMed

Racinais, Sebastien; Maffiuletti, Nicola A; Girard, Olivier

2013-08-01

To investigate whether the H reflex-M wave recruitment curves obtained during maximal voluntary contraction (MVC) differ from rest and to determine the stimulation intensities allowing to record stable reflex responses. Full recruitment curves (precision, 2 mA) were obtained from the soleus muscle in 14 volunteers at rest and during plantar flexion MVCs. Maximal M-wave reached significantly larger amplitude during MVC (+2.2 [0.4; 3.9] mV) for a higher stimulation intensity (+7.9 [-0.4; 16] mA). Similarly, maximal H-reflex reached significantly larger amplitude during MVC than at rest (+3.2 [0.9; 5.5] mV) for a much higher stimulation intensity (+17.7 [9.7; 25.7] mA). V-wave amplitude plateaued only when M-wave during MVC plateaued, that is, at higher intensity than M-wave at rest. V-wave was correlated to the maximal H-reflex during MVC (r = 0.79, P < 0.05). Electrically evoked potentials showed a specific recruitment curve during MVC with higher maximal values attained for higher stimulation intensities. Thus, recording reflex responses during MVC based on intensities determined at rest or as a percentage of M-wave may yield inaccurate results. V-wave presented a plateau for stimulation intensity of 1.5 times the onset of the resting M-wave plateau. Evoked potentials obtained during actual contractions should be normalized to M-waves obtained during contractions of the same force level.

Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012

PubMed Central

Bowman, Andrew S; Sreevatsan, Srinand; Killian, Mary L; Page, Shannon L; Nelson, Sarah W; Nolting, Jacqueline M; Cardona, Carol; Slemons, Richard D

2012-01-01

Evidence accumulating in 2011–2012 indicates that there is significant intra- and inter-species transmission of influenza A viruses at agricultural fairs, which has renewed interest in this unique human/swine interface. Six human cases of influenza A (H3N2) variant (H3N2v) virus infections were epidemiologically linked to swine exposure at fairs in the United States in 2011. In 2012, the number of H3N2v cases in the Midwest had exceeded 300 from early July to September, 2012. Prospective influenza A virus surveillance among pigs at Ohio fairs resulted in the detection of H3N2pM (H3N2 influenza A viruses containing the matrix (M) gene from the influenza A (H1N1) pdm09 virus). These H3N2pM viruses were temporally and spatially linked to several human H3N2v cases. Complete genomic analyses of these H3N2pM isolates demonstrated >99% nucleotide similarity to the H3N2v isolates recovered from human cases. Actions to mitigate the bidirectional interspecies transmission of influenza A virus between people and animals at agricultural fairs may be warranted. PMID:26038404

VizieR Online Data Catalog: M30 V1-V3 variable light curves (Rosino, 1949)

NASA Astrophysics Data System (ADS)

Rosino, L.

2013-05-01

Time-series photographic photometry for the variable stars V1-V3 in M30. We add the light curve of V1 from Rosini, 1961, Contr. Asiago-Padova, 117, "Osservazioni di due variabili peculiari e d'una variabile tipo RR Lyrae in ammassi stellari" (4 data files).

High Voltage SPT Performance

NASA Technical Reports Server (NTRS)

Manzella, David; Jacobson, David; Jankovsky, Robert

2001-01-01

A 2.3 kW stationary plasma thruster designed to operate at high voltage was tested at discharge voltages between 300 and 1250 V. Discharge specific impulses between 1600 and 3700 sec were demonstrated with thrust between 40 and 145 mN. Test data indicated that discharge voltage can be optimized for maximum discharge efficiency. The optimum discharge voltage was between 500 and 700 V for the various anode mass flow rates considered. The effect of operating voltage on optimal magnet field strength was investigated. The effect of cathode flow rate on thruster efficiency was considered for an 800 V discharge.

32 CFR 700.710 - Organization of a staff.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 5 2010-07-01 2010-07-01 false Organization of a staff. 700.710 Section 700.710... Commanders Staffs of Commanders § 700.710 Organization of a staff. (a) The term “staff” means those officers... operation of his or her command. (b) The officer detailed as chief of staff and aide to a fleet admiral or...

32 CFR 700.710 - Organization of a staff.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Organization of a staff. 700.710 Section 700.710... Commanders Staffs of Commanders § 700.710 Organization of a staff. (a) The term “staff” means those officers... operation of his or her command. (b) The officer detailed as chief of staff and aide to a fleet admiral or...

32 CFR 700.710 - Organization of a staff.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Organization of a staff. 700.710 Section 700.710... Commanders Staffs of Commanders § 700.710 Organization of a staff. (a) The term “staff” means those officers... operation of his or her command. (b) The officer detailed as chief of staff and aide to a fleet admiral or...

32 CFR 700.710 - Organization of a staff.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Organization of a staff. 700.710 Section 700.710... Commanders Staffs of Commanders § 700.710 Organization of a staff. (a) The term “staff” means those officers... operation of his or her command. (b) The officer detailed as chief of staff and aide to a fleet admiral or...

32 CFR 700.710 - Organization of a staff.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Organization of a staff. 700.710 Section 700.710... Commanders Staffs of Commanders § 700.710 Organization of a staff. (a) The term “staff” means those officers... operation of his or her command. (b) The officer detailed as chief of staff and aide to a fleet admiral or...

Biokinetics and dosimetric studies about 99mTc(V)-DMSA distribution.

PubMed

Correia, M B L; Magnata, S S L P; Silva, I M S; Catanho, M T J A; Lima, F F

2010-05-10

Research for radiodiagnostic agents should considerate biological critical parameters which will give own contribution on the absorbed dose. The dimercaptosuccinic acid (DMSA) labeled with (99m)Tc(V) is a radiopharmaceutical which has well established role in medullar thyroid carcinoma and has been proposed in evaluation of bone metastasis. This work studied the biokinetics and dosimetry of (99m)Tc(V)-DMSA by animal model. The (99m)Tc(V)-DMSA was prepared from a (III)DMSA kit alkalized. Mice (n=5) received (99m)Tc(V)DMSA i.v., they were sacrificed (30 min, 1h, 5h and 12h), the organs excised and the activities measured by a gamma counter. The results were evaluated based on %activity/g and the absorbed dose was estimated (MIRDOSE 3.0 program) by extrapolation of data from animal to human scale. The results showed the majority of organs reached the top uptake at 30 min, the greatest kidney uptake was (4.81 +/- 1.38)% activity/g, while the bone presented its highest uptake at 1h (5.49+/- 0.47)% activity/g, after 1h all the organs had activity exponential decrease. The biokinetic profile of (99m)Tc(V)-DMSA was well established, allowing quantifying of residence time, and the radiation dose estimates were made for this agent. About the absorbed dose, the preliminary results showed higher value to bone, being the soft tissue dose relatively low.

The charge-energy-mass spectrometer for 0.3-300 keV/e ions on the AMPTE CCE

NASA Technical Reports Server (NTRS)

Gloeckler, G.; Ipavich, F. M.; Hamilton, D. C.; Lundgren, R. A.; Studemann, W.; Wilken, B.; Kremser, G.; Hovestadt, D.; Gliem, F.; Rieck, W.

1985-01-01

The charge-energy-mass (CHEM) spectrometer on the Charge Composition Explorer (CCE) has the function to measure the energy spectra, pitch-angle distributions, and ionization states of ions in the earth's magnetosphere and magnetosheath in the energy range from 0.3 to 300 keV/charge with a time resolution of less than 1 min. The obtained data will provide essential information on outstanding problems related to ion sources and dynamical processes of space plasmas and of suprathermal ions. A description of the CHEM experiment is given, taking into account the principle of operation, the sensor, the electronics, instrument characteristics, specifications, and requirements. Questions of postlaunch performance are also discussed.

Design and construction of high-sensitivity, infrared bolometers for operation at 300 mK

NASA Technical Reports Server (NTRS)

Alsop, D. C.; Inman, C.; Lange, A. E.; Wibanks, T.

1992-01-01

The design and construction of 300-mK composite bolometers developed for millimeter-wave astronomical observations are described. Graphite fibers are used as the electrical leads for the thermistor to reduce the thermal conductance and heat capacity associated with the leads. A mechanical suspension made of Nylon fibers provides the required thermal conductance. Electrical noise equivalent powers below 1 x 10 exp -16 W/sq rt Hz have been achieved for detectors with thermal time constants of 11 ms. The detectors were installed in a millimeter-wave photometer and used to perform observations of the cosmic microwave background from a balloonborne platform. The flight performance was consistent with the measured laboratory properties.

7 CFR 900.700 - Exemption from assessments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 8 2014-01-01 2014-01-01 false Exemption from assessments. 900.700 Section 900.700 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Assessment of...

7 CFR 900.700 - Exemption from assessments.

Code of Federal Regulations, 2012 CFR