29 CFR 1926.910 - Inspection after blasting.

Code of Federal Regulations, 2011 CFR

2011-07-01

... disconnected from the blasting machine, or where power switches are used, they shall be locked open or in the off position. (b) Sufficient time shall be allowed, not less than 15 minutes in tunnels, for the smoke...

29 CFR 1926.910 - Inspection after blasting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... disconnected from the blasting machine, or where power switches are used, they shall be locked open or in the off position. (b) Sufficient time shall be allowed, not less than 15 minutes in tunnels, for the smoke...

29 CFR 1926.910 - Inspection after blasting.

Code of Federal Regulations, 2014 CFR

2014-07-01

... disconnected from the blasting machine, or where power switches are used, they shall be locked open or in the off position. (b) Sufficient time shall be allowed, not less than 15 minutes in tunnels, for the smoke...

29 CFR 1926.910 - Inspection after blasting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... disconnected from the blasting machine, or where power switches are used, they shall be locked open or in the off position. (b) Sufficient time shall be allowed, not less than 15 minutes in tunnels, for the smoke...

Comparison of vacuum rise time, vacuum limit accuracy, and occlusion break surge of 3 new phacoemulsification systems.

PubMed

Han, Young Keun; Miller, Kevin M

2009-08-01

To compare vacuum rise time, vacuum limit accuracy, and occlusion break surge of 3 new phacoemulsification machines. Jules Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA. The vacuum rise time under normal and enhanced aspiration modes, vacuum limit accuracy, and occlusion break surge of the Infiniti Vision System, Stellaris Vision Enhancement System, and WhiteStar Signature Phacoemulsification System were tested. Vacuum rise time and limit accuracy were measured at limit settings of 400 mm Hg and 600 mm Hg. Surge area was recorded at vacuum limit settings of 200 mm Hg, 300 mm Hg, 400 mm Hg, and 500 mm Hg. The Infiniti had the fastest vacuum rise times under normal and enhanced aspiration modes. At 4 seconds, the vacuum limit accuracy was greatest with the Infiniti at the 400 mm Hg limit and the Signature at the 600 mm Hg limit. The Stellaris did not reach either vacuum target. The Infiniti performed better than the other 2 machines during testing of occlusion break surge at all vacuum limit settings above 200 mm Hg. Under controlled laboratory test conditions, the Infiniti had the fastest vacuum rise time, greatest vacuum limit accuracy at 400 mm Hg, and least occlusion break surge. These results can be explained by the lower compliance of the Infiniti system.

Implementations of BLAST for parallel computers.

PubMed

Jülich, A

1995-02-01

The BLAST sequence comparison programs have been ported to a variety of parallel computers-the shared memory machine Cray Y-MP 8/864 and the distributed memory architectures Intel iPSC/860 and nCUBE. Additionally, the programs were ported to run on workstation clusters. We explain the parallelization techniques and consider the pros and cons of these methods. The BLAST programs are very well suited for parallelization for a moderate number of processors. We illustrate our results using the program blastp as an example. As input data for blastp, a 799 residue protein query sequence and the protein database PIR were used.

Intrathoracic pressure variations in an anthropomorphic dummy exposed to air blast, blunt impact, and missiles.

PubMed

Jönsson, A; Arvebo, E; Schantz, B

1988-01-01

Experiments with an anthropomorphic dummy for blast research demonstrated that pressures recorded in the lung model of the dummy could be correlated to primary air blast effects on the lungs of experimental animals. The results presented here were obtained with a dummy of the type mentioned above, but with the lung model modified to improve geometric similarity to man. Blast experiments were performed in a shock tube, and impact experiments in a special impact machine. Experiments with nonpenetrating missiles were performed with small-caliber firearms and the dummy protected by body armor. Severity indices derived from the blast experiments were related to established criteria for primary lung injury in man. Impacts delivered in the impact machine and by nonpenetrating missiles are compared. Relationships between severity of impact based on experiments with animals and primary lung injury in man are discussed.

New Single Piece Blast Hardware design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ulrich, Andri; Steinzig, Michael Louis; Aragon, Daniel Adrian

W, Q and PF engineers and machinists designed and fabricated, on the new Mazak i300, the first Single Piece Blast Hardware (unclassified design shown) reducing fabrication and inspection time by over 50%. The first DU Single Piece is completed and will be used for Hydro Test 3680. Past hydro tests used a twopiece assembly due to a lack of equipment capable of machining the complex saddle shape in a single piece. The i300 provides turning and milling 5-axis machining on one machine. The milling head on the i300 can machine past 90 relative to the spindle axis. This makes itmore » possible to machine the complex saddle surface on a single piece. Going to a single piece eliminates tolerance problems, such as tilting and eccentricity, that typically occurred when assembling the two pieces together« less

An Experimental Study on the Fabrication of Glass-based Acceleration Sensor Body Using Micro Powder Blasting Method

PubMed Central

Park, Dong-Sam; Yun, Dae-Jin; Cho, Myeong-Woo; Shin, Bong-Cheol

2007-01-01

This study investigated the feasibility of the micro powder blasting technique for the micro fabrication of sensor structures using the Pyrex glass to replace the existing silicon-based acceleration sensor fabrication processes. As the preliminary experiments, the effects of the blasting pressure, the mass flow rate of abrasive and the number of nozzle scanning times on erosion depth of the Pyrex and the soda lime glasses were examined. From the experimental results, optimal blasting conditions were selected for the Pyrex glass machining. The dimensions of the designed glass sensor was 1.7×1.7×0.6mm for the vibrating mass, and 2.9×0.7×0.2mm for the cantilever beam. The machining results showed that the dimensional errors of the machined glass sensor ranged from 3 μm in minimum to 20 μm in maximum. These results imply that the micro powder blasting method can be applied for the micromachining of glass-based acceleration sensors to replace the exiting method.

13. Photocopied August 1978. ROCK DRILLING MACHINES, NOVEMBER 23, 1898. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Photocopied August 1978. ROCK DRILLING MACHINES, NOVEMBER 23, 1898. THE HOLES DRILLED BY THESE MACHINES WERE PACKED WITH GUNPOWDER FOR BLASTING. (19) - Michigan Lake Superior Power Company, Portage Street, Sault Ste. Marie, Chippewa County, MI

Micro Dot Patterning on the Light Guide Panel Using Powder Blasting

PubMed Central

Jang, Ho Su; Cho, Myeong Woo; Park, Dong Sam

2008-01-01

This study is to develop a micromachining technology for a light guide panel(LGP) mold, whereby micro dot patterns are formed on a LGP surface by a single injection process instead of existing screen printing processes. The micro powder blasting technique is applied to form micro dot patterns on the LGP mold surface. The optimal conditions for masking, laminating, exposure, and developing processes to form the micro dot patterns are first experimentally investigated. A LGP mold with masked micro patterns is then machined using the micro powder blasting method and the machinability of the micro dot patterns is verified. A prototype LGP is test- injected using the developed LGP mold and a shape analysis of the patterns and performance testing of the injected LGP are carried out. As an additional approach, matte finishing, a special surface treatment method, is applied to the mold surface to improve the light diffusion characteristics, uniformity and brightness of the LGP. The results of this study show that the applied powder blasting method can be successfully used to manufacture LGPs with micro patterns by just single injection using the developed mold and thereby replace existing screen printing methods. PMID:27879740

Machining of Aircraft Titanium with Abrasive-Waterjets for Fatigue Critical Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, H. T.; Hovanski, Yuri; Dahl, Michael E.

2010-10-04

Laboratory tests were conducted to determine the fatigue performance of AWJ-machined aircraft titanium. Dog-bone specimens machined with AWJs were prepared and tested with and without sanding and dry-grit blasting with Al2O3 as secondary processes. The secondary processes were applied to remove the visual appearance of AWJ-generated striations and to clean up the garnet embedment. The fatigue performance of AWJ-machined specimens was compared with baseline specimens machined with CNC milling. Fatigue test results not only confirmed the findings of the aluminum dog-bone specimens but also further enhance the fatigue performance. In addition, titanium is known to be notoriously difficult to cutmore » with contact tools while AWJs cut it 34% faster than stainless steel. AWJ cutting and dry-grit blasting are shown to be a preferred combination for processing aircraft titanium that is fatigue critical.« less

Technology Development of Salak (Salacca Zalacca) Chips With Vacuum Frying Machine Base On Expert System In Kramat-Bangkalan Regency

NASA Astrophysics Data System (ADS)

Rosida, D. F.; Happyanto; Anggraeni; Sugiarto; Hapsari

2018-01-01

Agropolitan Program is one form of regional development to improve agribusiness system and effort to improve the welfare of the community. One of the leading commodities in Bangkalan agroclimates is salak which is a potentially very large commodity to be developed. Salak commodities in Kramat Bangkalan Indonesia have developed varous salak produced such as dates of salak, syrup and dodol salak. Salak chips was the target of innovation from processed salak. The Production of salak chips using frying technology with vacuum system to obtain crunchy chips. To get the results need to be developed synergy technology to combine the process conditions and the right system in producing good quality salak chips. Bangkalan Regency is the potential to continue to develop products using a variety of salak to the processed form of vacuum frying machine based on expert system so that the resulting product would be great texture, aroma and taste. This will make the area of Bangkalan, Indonesia be more independent in producing and increasing revenue.

Machining of Aircraft Titanium with Abrasive-Waterjets for Fatigue Critical Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, H. T.; Hovanski, Yuri; Dahl, Michael E.

2012-02-01

Laboratory tests were conducted to determine the fatigue performance of abrasive-waterjet- (AWJ-) machined aircraft titanium. Dog-bone specimens machined with AWJs were prepared and tested with and without sanding and dry-grit blasting with Al2O3 as secondary processes. The secondary processes were applied to remove the visual appearance of AWJ-generated striations and to clean up the garnet embedment. The fatigue performance of AWJ-machined specimens was compared with baseline specimens machined with CNC milling. Fatigue test results of the titanium specimens not only confirmed our previous findings in aluminum dog-bone specimens but in comparison also further enhanced the fatigue performance of the titanium.more » In addition, titanium is known to be difficult to cut, particularly for thick parts, however AWJs cut the material 34% faster han stainless steel. AWJ cutting and dry-grit blasting are shown to be a preferred ombination for processing aircraft titanium that is fatigue critical.« less

Vacuum collection of Douglas-fir pollen for supplemental mass pollinations.

Treesearch

D.L. Copes; N.C. Vance; W.K. Randall; A. Jasumback; R. Hallman

1991-01-01

An Aget Cyclone dust collector and peripheral equipment were fieldtested for use in vacuuming large quantities of pollen from 30- to 40-foot trees in a Douglas-fir seed orchard. The Cyclone machine (Model 20SN31P) operated without a vacuum bag or filter device, so no blockage or reduction in vacuum efficiency occurred when large volumes of pollen were collected....

Application of Abrasive-Waterjets for Machining Fatigue-Critical Aircraft Aluminum Parts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, H T; Hovanski, Yuri; Dahl, Michael E

2010-08-19

Current specifications require AWJ-cut aluminum parts for fatigue critical aerospace structures to go through subsequent processing due to concerns of degradation in fatigue performance. The requirement of secondary process for AWJ-machined parts greatly negates the cost effectiveness of waterjet technology. Some cost savings are envisioned if it can be shown that AWJ net cut parts have comparable durability properties as those conventionally machined. To revisit and upgrade the specifications for AWJ machining of aircraft aluminum, “Dog-bone” specimens, with and without secondary processes, were prepared for independent fatigue tests at Boeing and Pacific Northwest National Laboratory (PNNL). Test results show thatmore » the fatigue life is proportional to quality levels of machined edges or inversely proportional to the surface roughness Ra . Even at highest quality level, the average fatigue life of AWJ-machined parts is about 30% shorter than those of conventionally machined counterparts. Between two secondary processes, dry-grit blasting with aluminum oxide abrasives until the striation is removed visually yields excellent result. It actually prolongs the fatigue life of parts at least three times higher than that achievable with conventional machining. Dry-grit blasting is relatively simple and inexpensive to administrate and, equally important, alleviates the concerns of garnet embedment.« less

Testing of machine wound second generation HTS tape Vacuum Pressure Impregnated coils

NASA Astrophysics Data System (ADS)

Swaffield, D.; Lewis, C.; Eugene, J.; Ingles, M.; Peach, D.

2014-05-01

Delamination of second generation (2G) High Temperature Superconducting (HTS) tapes has previously been reported when using resin based insulation systems for wound coils. One proposed root cause is the differential thermal contraction between the coil former and the resin encapsulated coil turns resulting in the tape c-axis tensile stress being exceeded. Importantly, delamination results in unacceptable degradation of the superconductor critical current level. To mitigate the delamination risk and prove winding, jointing and Vacuum Pressure Impregnation (VPI) processes in the production of coils for superconducting rotating machines at GE Power Conversion two scaled trial coils have been wound and extensively tested. The coils are wound from 12mm wide 2G HTS tape supplied by AMSC onto stainless steel 'racetrack' coil formers. The coils are wound in two layers which include both in-line and layer-layer joints subject to in-process test. The resin insulation system chosen is VPI and oven cured. Tests included; insulation resistance, repeat quench and recovery of the superconductor, heat runs and measurement of n-value, before and after multiple thermal cycling between ambient and 35 Kelvin. No degradation of coil performance is evidenced.

A Novel Online Sequential Extreme Learning Machine for Gas Utilization Ratio Prediction in Blast Furnaces.

PubMed

Li, Yanjiao; Zhang, Sen; Yin, Yixin; Xiao, Wendong; Zhang, Jie

2017-08-10

Gas utilization ratio (GUR) is an important indicator used to measure the operating status and energy consumption of blast furnaces (BFs). In this paper, we present a soft-sensor approach, i.e., a novel online sequential extreme learning machine (OS-ELM) named DU-OS-ELM, to establish a data-driven model for GUR prediction. In DU-OS-ELM, firstly, the old collected data are discarded gradually and the newly acquired data are given more attention through a novel dynamic forgetting factor (DFF), depending on the estimation errors to enhance the dynamic tracking ability. Furthermore, we develop an updated selection strategy (USS) to judge whether the model needs to be updated with the newly coming data, so that the proposed approach is more in line with the actual production situation. Then, the convergence analysis of the proposed DU-OS-ELM is presented to ensure the estimation of output weight converge to the true value with the new data arriving. Meanwhile, the proposed DU-OS-ELM is applied to build a soft-sensor model to predict GUR. Experimental results demonstrate that the proposed DU-OS-ELM obtains better generalization performance and higher prediction accuracy compared with a number of existing related approaches using the real production data from a BF and the created GUR prediction model can provide an effective guidance for further optimization operation.

A Novel Online Sequential Extreme Learning Machine for Gas Utilization Ratio Prediction in Blast Furnaces

PubMed Central

Li, Yanjiao; Yin, Yixin; Xiao, Wendong; Zhang, Jie

2017-01-01

Gas utilization ratio (GUR) is an important indicator used to measure the operating status and energy consumption of blast furnaces (BFs). In this paper, we present a soft-sensor approach, i.e., a novel online sequential extreme learning machine (OS-ELM) named DU-OS-ELM, to establish a data-driven model for GUR prediction. In DU-OS-ELM, firstly, the old collected data are discarded gradually and the newly acquired data are given more attention through a novel dynamic forgetting factor (DFF), depending on the estimation errors to enhance the dynamic tracking ability. Furthermore, we develop an updated selection strategy (USS) to judge whether the model needs to be updated with the newly coming data, so that the proposed approach is more in line with the actual production situation. Then, the convergence analysis of the proposed DU-OS-ELM is presented to ensure the estimation of output weight converge to the true value with the new data arriving. Meanwhile, the proposed DU-OS-ELM is applied to build a soft-sensor model to predict GUR. Experimental results demonstrate that the proposed DU-OS-ELM obtains better generalization performance and higher prediction accuracy compared with a number of existing related approaches using the real production data from a BF and the created GUR prediction model can provide an effective guidance for further optimization operation. PMID:28796187

miBLAST: scalable evaluation of a batch of nucleotide sequence queries with BLAST

PubMed Central

Kim, You Jung; Boyd, Andrew; Athey, Brian D.; Patel, Jignesh M.

2005-01-01

A common task in many modern bioinformatics applications is to match a set of nucleotide query sequences against a large sequence dataset. Exis-ting tools, such as BLAST, are designed to evaluate a single query at a time and can be unacceptably slow when the number of sequences in the query set is large. In this paper, we present a new algorithm, called miBLAST, that evaluates such batch workloads efficiently. At the core, miBLAST employs a q-gram filtering and an index join for efficiently detecting similarity between the query sequences and database sequences. This set-oriented technique, which indexes both the query and the database sets, results in substantial performance improvements over existing methods. Our results show that miBLAST is significantly faster than BLAST in many cases. For example, miBLAST aligned 247 965 oligonucleotide sequences in the Affymetrix probe set against the Human UniGene in 1.26 days, compared with 27.27 days with BLAST (an improvement by a factor of 22). The relative performance of miBLAST increases for larger word sizes; however, it decreases for longer queries. miBLAST employs the familiar BLAST statistical model and output format, guaranteeing the same accuracy as BLAST and facilitating a seamless transition for existing BLAST users. PMID:16061938

Dry ice blasting

NASA Astrophysics Data System (ADS)

Lonergan, Jeffrey M.

1992-04-01

As legal and societal pressures against the use of hazardous waste generating materials has increased, so has the motivation to find safe, effective, and permanent replacements. Dry ice blasting is a technology which uses CO2 pellets as a blasting medium. The use of CO2 for cleaning and stripping operations offers potential for significant environmental, safety, and productivity improvements over grit blasting, plastic media blasting, and chemical solvent cleaning. Because CO2 pellets break up and sublime upon impact, there is no expended media to dispose of. Unlike grit or plastic media blasting which produce large quantities of expended media, the only waste produced by CO2 blasting is the material removed. The quantity of hazardous waste produced, and thus the cost of hazardous waste disposal is significantly reduced.

Diffraction-limited storage-ring vacuum technology

PubMed Central

Al-Dmour, Eshraq; Ahlback, Jonny; Einfeld, Dieter; Tavares, Pedro Fernandes; Grabski, Marek

2014-01-01

Some of the characteristics of recent ultralow-emittance storage-ring designs and possibly future diffraction-limited storage rings are a compact lattice combined with small magnet apertures. Such requirements present a challenge for the design and performance of the vacuum system. The vacuum system should provide the required vacuum pressure for machine operation and be able to handle the heat load from synchrotron radiation. Small magnet apertures result in the conductance of the chamber being low, and lumped pumps are ineffective. One way to provide the required vacuum level is by distributed pumping, which can be realised by the use of a non-evaporable getter (NEG) coating of the chamber walls. It may not be possible to use crotch absorbers to absorb the heat from the synchrotron radiation because an antechamber is difficult to realise with such a compact lattice. To solve this, the chamber walls can work as distributed absorbers if they are made of a material with good thermal conductivity, and distributed cooling is used at the location where the synchrotron radiation hits the wall. The vacuum system of the 3 GeV storage ring of MAX IV is used as an example of possible solutions for vacuum technologies for diffraction-limited storage rings. PMID:25177979

Effect of mesh-peel ply variation on mechanical properties of E-glas composite by infusion vacuum method

NASA Astrophysics Data System (ADS)

Abdurohman, K.; Siahaan, Mabe

2018-04-01

Composite materials made of glass fiber EW-135 with epoxy lycal resin with vacuum infusion method have been performed. The dried glass fiber is arranged in a mold then connected to a vacuum machine and a resin tube. Then, the vacuum machine is turned on and at the same time the resin is sucked and flowed into the mold. This paper reports on the effect of using mesh- peel ply singles on upper-side laminates called A and the effect of using double mesh-peel ply on upper and lower-side laminates call B with glass fiber arrangement is normal and ± 450 in vacuum infusion process. Followed by the manufacture of tensile test specimen and tested its tensile strength with universal test machine 100kN Tensilon RTF 2410, at room temperature with constant crosshead speed. From tensile test results using single and double layers showed that double mesh-peel ply can increase tensile strength 14% and Young modulus 17%.

GeneMachine: gene prediction and sequence annotation.

PubMed

Makalowska, I; Ryan, J F; Baxevanis, A D

2001-09-01

A number of free-standing programs have been developed in order to help researchers find potential coding regions and deduce gene structure for long stretches of what is essentially 'anonymous DNA'. As these programs apply inherently different criteria to the question of what is and is not a coding region, multiple algorithms should be used in the course of positional cloning and positional candidate projects to assure that all potential coding regions within a previously-identified critical region are identified. We have developed a gene identification tool called GeneMachine which allows users to query multiple exon and gene prediction programs in an automated fashion. BLAST searches are also performed in order to see whether a previously-characterized coding region corresponds to a region in the query sequence. A suite of Perl programs and modules are used to run MZEF, GENSCAN, GRAIL 2, FGENES, RepeatMasker, Sputnik, and BLAST. The results of these runs are then parsed and written into ASN.1 format. Output files can be opened using NCBI Sequin, in essence using Sequin as both a workbench and as a graphical viewer. The main feature of GeneMachine is that the process is fully automated; the user is only required to launch GeneMachine and then open the resulting file with Sequin. Annotations can then be made to these results prior to submission to GenBank, thereby increasing the intrinsic value of these data. GeneMachine is freely-available for download at http://genome.nhgri.nih.gov/genemachine. A public Web interface to the GeneMachine server for academic and not-for-profit users is available at http://genemachine.nhgri.nih.gov. The Web supplement to this paper may be found at http://genome.nhgri.nih.gov/genemachine/supplement/.

Vacuum plasma coatings for turbine blades

NASA Technical Reports Server (NTRS)

Holmes, R. R.

1985-01-01

Turbine blades, vacuum plasma spray coated with NiCrAlY, CoCrAlY or NiCrAlY/Cr2O3, were evaluated and rated superior to standard space shuttle main engine (SSME) coated blades. Ratings were based primarily on 25 thermal cycles in the MSFC Burner Rig Tester, cycling between 1700 F (gaseous H2) and -423 F (liquid H2). These tests showed no spalling on blades with improved vacuum plasma coatings, while standard blades spalled. Thermal barrier coatings of ZrO2, while superior to standard coatings, lacked the overall performance desired. Fatigue and tensile specimens, machined from MAR-M-246(Hf) test bars identical to the blades were vacuum plasma spray coated, diffusion bond treated, and tested to qualify the vacuum plasma spray process for flight hardware testing and application. While NiCrAlY/Cr2O3 offers significant improvement over standard coatings in durability and thermal protection, studies continue with an objective to develop coatings offering even greater improvements.

Development of High vacuum facility for baking and cool down experiments for SST-1 Tokamak components

NASA Astrophysics Data System (ADS)

Khan, Ziauddin; Pathan, Firozkhan S.; Yuvakiran, Paravastu; George, Siju; Manthena, Himabindu; Raval, Dilip C.; Thankey, Prashant L.; Dhanani, Kalpesh R.; Gupta, Manoj Kumar; Pradhan, Subrata

2012-11-01

SST-1 Tokamak, a steady state super-conducting device, is under refurbishment to demonstrate the plasma discharge for the duration of 1000 second. The major fabricated components of SST-1 like vacuum vessel, thermal shields, superconducting magnets etc have to be tested for their functional parameters. During machine operation, vacuum vessel will be baked at 150 °C, thermal shields will be operated at 85 K and magnet system will be operated at 4.5 K. All these components must have helium leak tightness under these conditions so far as the machine operation is concerned. In order to validate the helium leak tightness of these components, in-house high vacuum chamber is fabricated. This paper describes the analysis, design and fabrication of high vacuum chamber to demonstrate these functionalities. Also some results will be presented.

Blast injury research models

PubMed Central

Kirkman, E.; Watts, S.; Cooper, G.

2011-01-01

Blast injuries are an increasing problem in both military and civilian practice. Primary blast injury to the lungs (blast lung) is found in a clinically significant proportion of casualties from explosions even in an open environment, and in a high proportion of severely injured casualties following explosions in confined spaces. Blast casualties also commonly suffer secondary and tertiary blast injuries resulting in significant blood loss. The presence of hypoxaemia owing to blast lung complicates the process of fluid resuscitation. Consequently, prolonged hypotensive resuscitation was found to be incompatible with survival after combined blast lung and haemorrhage. This article describes studies addressing new forward resuscitation strategies involving a hybrid blood pressure profile (initially hypotensive followed later by normotensive resuscitation) and the use of supplemental oxygen to increase survival and reduce physiological deterioration during prolonged resuscitation. Surprisingly, hypertonic saline dextran was found to be inferior to normal saline after combined blast injury and haemorrhage. New strategies have therefore been developed to address the needs of blast-injured casualties and are likely to be particularly useful under circumstances of enforced delayed evacuation to surgical care. PMID:21149352

A fluidics comparison of Alcon Infiniti, Bausch & Lomb Stellaris, and Advanced Medical Optics Signature phacoemulsification machines.

PubMed

Georgescu, Dan; Kuo, Annie F; Kinard, Krista I; Olson, Randall J

2008-06-01

To compare three phacoemulsification machines for measurement accuracy and postocclusion surge (POS) in human cadaver eyes. In vitro comparisons of machine accuracy and POS. Tip vacuum and flow were compared with machine indicated vacuum and flow. All machines were placed in two human cadaver eyes and POS was determined. Vacuum (% of actual) was 101.9% +/- 1.7% for Infiniti (Alcon, Fort Worth, Texas, USA), 93.2% +/- 3.9% for Stellaris (Bausch & Lomb, Rochester, New York, USA), and 107.8% +/- 4.6% for Signature (Advanced Medical Optics, Santa, Ana, California, USA; P < .0001). At 60 ml/minute flow, actual flow and unoccluded flow vacuum (UFV) was 55.8 +/- 0.4 ml/minute and 197.7 +/- 0.7 mm Hg for Infiniti, 53.5 +/- 0.0 ml/minute and 179.8 +/- 0.9 mm Hg for Stellaris, and 58.5 +/- 0.0 ml/minute and 115.1 +/- 2.3 mm Hg for Signature (P < .0001). POS in an 32-year-old eye was 0.33 +/- 0.05 mm for Infiniti, 0.16 +/- 0.06 mm for Stellaris, and 0.13 +/- 0.04 mm for Signature at 550 mm Hg, 60 cm bottle height, 45 ml/minute flow with 19-gauge tips (P < .0001 for Infiniti vs Stellaris and Signature). POS in an 81-year-old eye was 1.51 +/- 0.22 mm for Infiniti, 0.83 +/- 0.06 mm for Stellaris, 0.67 +/- 0.01 mm for Signature at 400 mm Hg vacuum, 70 cm bottle height, 40 ml/minute flow with 19-gauge tips (P < .0001). Machine-indicated accuracy, POS, and UFV were statistically significantly different. Signature had the lowest POS and vacuum to maintain flow. Regarding POS, Stellaris was close to Signature; regarding vacuum to maintain flow, Infiniti and Stellaris were similar. Minimizing POS and vacuum to maintain flow potentially are important in avoiding ocular damage and surgical complications.

Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model

PubMed Central

Goldstein, Lee E.; Fisher, Andrew M.; Tagge, Chad A.; Zhang, Xiao-Lei; Velisek, Libor; Sullivan, John A.; Upreti, Chirag; Kracht, Jonathan M.; Ericsson, Maria; Wojnarowicz, Mark W.; Goletiani, Cezar J.; Maglakelidze, Giorgi M.; Casey, Noel; Moncaster, Juliet A.; Minaeva, Olga; Moir, Robert D.; Nowinski, Christopher J.; Stern, Robert A.; Cantu, Robert C.; Geiling, James; Blusztajn, Jan K.; Wolozin, Benjamin L.; Ikezu, Tsuneya; Stein, Thor D.; Budson, Andrew E.; Kowall, Neil W.; Chargin, David; Sharon, Andre; Saman, Sudad; Hall, Garth F.; Moss, William C.; Cleveland, Robin O.; Tanzi, Rudolph E.; Stanton, Patric K.; McKee, Ann C.

2013-01-01

Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms, and long-term cognitive disability. We examined a case series of postmortem brains from U.S. military veterans exposed to blast and/or concussive injury. We found evidence of chronic traumatic encephalopathy (CTE), a tau protein–linked neurodegenerative disease, that was similar to the CTE neuropathology observed in young amateur American football players and a professional wrestler with histories of concussive injuries. We developed a blast neurotrauma mouse model that recapitulated CTE-linked neuropathology in wild-type C57BL/6 mice 2 weeks after exposure to a single blast. Blast-exposed mice demonstrated phosphorylated tauopathy, myelinated axonopathy, microvasculopathy, chronic neuroinflammation, and neurodegeneration in the absence of macroscopic tissue damage or hemorrhage. Blast exposure induced persistent hippocampal-dependent learning and memory deficits that persisted for at least 1 month and correlated with impaired axonal conduction and defective activity-dependent long-term potentiation of synaptic transmission. Intracerebral pressure recordings demonstrated that shock waves traversed the mouse brain with minimal change and without thoracic contributions. Kinematic analysis revealed blast-induced head oscillation at accelerations sufficient to cause brain injury. Head immobilization during blast exposure prevented blast-induced learning and memory deficits. The contribution of blast wind to injurious head acceleration may be a primary injury mechanism leading to blast-related TBI and CTE. These results identify common pathogenic determinants leading to CTE in blast-exposed military veterans and head-injured athletes and additionally provide mechanistic evidence linking blast exposure to persistent impairments in neurophysiological function, learning, and memory. PMID:22593173

Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

PubMed

Goldstein, Lee E; Fisher, Andrew M; Tagge, Chad A; Zhang, Xiao-Lei; Velisek, Libor; Sullivan, John A; Upreti, Chirag; Kracht, Jonathan M; Ericsson, Maria; Wojnarowicz, Mark W; Goletiani, Cezar J; Maglakelidze, Giorgi M; Casey, Noel; Moncaster, Juliet A; Minaeva, Olga; Moir, Robert D; Nowinski, Christopher J; Stern, Robert A; Cantu, Robert C; Geiling, James; Blusztajn, Jan K; Wolozin, Benjamin L; Ikezu, Tsuneya; Stein, Thor D; Budson, Andrew E; Kowall, Neil W; Chargin, David; Sharon, Andre; Saman, Sudad; Hall, Garth F; Moss, William C; Cleveland, Robin O; Tanzi, Rudolph E; Stanton, Patric K; McKee, Ann C

2012-05-16

Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms, and long-term cognitive disability. We examined a case series of postmortem brains from U.S. military veterans exposed to blast and/or concussive injury. We found evidence of chronic traumatic encephalopathy (CTE), a tau protein-linked neurodegenerative disease, that was similar to the CTE neuropathology observed in young amateur American football players and a professional wrestler with histories of concussive injuries. We developed a blast neurotrauma mouse model that recapitulated CTE-linked neuropathology in wild-type C57BL/6 mice 2 weeks after exposure to a single blast. Blast-exposed mice demonstrated phosphorylated tauopathy, myelinated axonopathy, microvasculopathy, chronic neuroinflammation, and neurodegeneration in the absence of macroscopic tissue damage or hemorrhage. Blast exposure induced persistent hippocampal-dependent learning and memory deficits that persisted for at least 1 month and correlated with impaired axonal conduction and defective activity-dependent long-term potentiation of synaptic transmission. Intracerebral pressure recordings demonstrated that shock waves traversed the mouse brain with minimal change and without thoracic contributions. Kinematic analysis revealed blast-induced head oscillation at accelerations sufficient to cause brain injury. Head immobilization during blast exposure prevented blast-induced learning and memory deficits. The contribution of blast wind to injurious head acceleration may be a primary injury mechanism leading to blast-related TBI and CTE. These results identify common pathogenic determinants leading to CTE in blast-exposed military veterans and head-injured athletes and additionally provide mechanistic evidence linking blast exposure to persistent impairments in neurophysiological function, learning, and memory.

Blast Injuries: From Improvised Explosive Device Blasts to the Boston Marathon Bombing.

PubMed

Singh, Ajay K; Ditkofsky, Noah G; York, John D; Abujudeh, Hani H; Avery, Laura A; Brunner, John F; Sodickson, Aaron D; Lev, Michael H

2016-01-01

Although most trauma centers have experience with the imaging and management of gunshot wounds, in most regions blast wounds such as the ones encountered in terrorist attacks with the use of improvised explosive devices (IEDs) are infrequently encountered outside the battlefield. As global terrorism becomes a greater concern, it is important that radiologists, particularly those working in urban trauma centers, be aware of the mechanisms of injury and the spectrum of primary, secondary, tertiary, and quaternary blast injury patterns. Primary blast injuries are caused by barotrauma from the initial increased pressure of the explosive detonation and the rarefaction of the atmosphere immediately afterward. Secondary blast injuries are caused by debris carried by the blast wind and most often result in penetrating trauma from small shrapnel. Tertiary blast injuries are caused by the physical displacement of the victim and the wide variety of blunt or penetrating trauma sustained as a result of the patient impacting immovable objects such as surrounding cars, walls, or fences. Quaternary blast injuries include all other injuries, such as burns, crush injuries, and inhalational injuries. Radiography is considered the initial imaging modality for assessment of shrapnel and fractures. Computed tomography is the optimal test to assess penetrating chest, abdominal, and head trauma. The mechanism of blast injuries and the imaging experience of the victims of the Boston Marathon bombing are detailed, as well as musculoskeletal, neurologic, gastrointestinal, and pulmonary injury patterns from blast injuries. ©RSNA, 2016.

Passive blast pressure sensor

DOEpatents

King, Michael J.; Sanchez, Roberto J.; Moss, William C.

2013-03-19

A passive blast pressure sensor for detecting blast overpressures of at least a predetermined minimum threshold pressure. The blast pressure sensor includes a piston-cylinder arrangement with one end of the piston having a detection surface exposed to a blast event monitored medium through one end of the cylinder and the other end of the piston having a striker surface positioned to impact a contact stress sensitive film that is positioned against a strike surface of a rigid body, such as a backing plate. The contact stress sensitive film is of a type which changes color in response to at least a predetermined minimum contact stress which is defined as a product of the predetermined minimum threshold pressure and an amplification factor of the piston. In this manner, a color change in the film arising from impact of the piston accelerated by a blast event provides visual indication that a blast overpressure encountered from the blast event was not less than the predetermined minimum threshold pressure.

Comparison of Some Blast Vibration Predictors for Blasting in Underground Drifts and Some Observations

NASA Astrophysics Data System (ADS)

Bhagwat, Vaibhab Pramod; Dey, Kaushik

2016-04-01

Drilling and blasting are the most economical excavation techniques in underground drifts driven through hard rock formation. Burn cut is the most popular drill pattern, used in this case, to achieve longer advance per blast round. The ground vibration generated due to the propagation of blast waves on the detonation of explosive during blasting is the principal cause for structural and rock damage. Thus, ground vibration is a point of concern for the blasting engineers. The ground vibration from a blast is measured using a seismograph placed at the blast monitoring station. The measured vibrations, in terms of peak particle velocity, are related to the maximum charge detonated at one instant and the distance of seismograph from the blast point. The ground vibrations from a number of blast rounds of varying charge/delay and distances are monitored. A number of scaling factors of these dependencies (viz. Distance and maximum charge/delay) have been proposed by different researchers, namely, square root, cube root, CMRI, Langefors and Kihlstrom, Ghosh-Daemon, Indian standard etc. Scaling factors of desired type are computed for all the measured blast rounds. Regression analysis is carried out between the scaling factors and peak particle velocities to establish the coefficients of the vibration predictor equation. Then, the developed predictor equation is used for designing the blast henceforth. Director General of Mine Safety, India, specified that ground vibrations from eight to ten blast rounds of varying charge/delay and distances should be monitored to develop a predictor equation; however, there is no guideline about the type of scaling factor to be used. Further to this, from the statistical point of view, a regression analysis on a small sample population cannot be accepted without the testing of hypothesis. To show the importance of the above, in this paper, seven scaling factors are considered for blast data set of a hard-rock underground drift using burn

Evaluation of Vacuum Blasting and Heat Guns as Methods for Abating Lead- Based Paint on Buildings

DTIC Science & Technology

1993-09-01

INCOMPATIBILITY - Contact with powerful oxidizing agents such as FLUORINE, CHLORINE TRIFLUORIDE , MANGANESE TRIOXIDE, OXYGEN DIFLUORIDE, MANGANESE...investigating new technologies for lead-based paint abatement. This research evaluates the effectiveness , safety, LEC1L•.T• and cost of vacuum abrasive...paint abatement. This research evaluates the effectiveness , safety, and cost of vacuum abrasive units and heat guns as methods of removing lead-based

Blast lung injury.

PubMed

Sasser, Scott M; Sattin, Richard W; Hunt, Richard C; Krohmer, Jon

2006-01-01

Current trends in global terrorism mandate that emergency medical services, emergency medicine and other acute care clinicians have a basic understanding of the physics of explosions, the types of injuries that can result from an explosion, and current management for patients injured by explosions. High-order explosive detonations result in near instantaneous transformation of the explosive material into a highly pressurized gas, releasing energy at supersonic speeds. This results in the formation of a blast wave that travels out from the epicenter of the blast. Primary blast injuries are characterized by anatomical and physiological changes from the force generated by the blast wave impacting the body's surface, and affect primarily gas-containing structures (lungs, gastrointestinal tract, ears). "Blast lung" is a clinical diagnosis and is characterized as respiratory difficulty and hypoxia without obvious external injury to the chest. It may be complicated by pneumothoraces and air emboli and may be associated with multiple other injuries. Patients may present with a variety of symptoms, including dyspnea, chest pain, cough, and hemoptysis. Physical examination may reveal tachypnea, hypoxia, cyanosis, and decreased breath sounds. Chest radiography, computerized tomography, and arterial blood gases may assist with diagnosis and management; however, they should not delay diagnosis and emergency interventions in the patient exposed to a blast. High flow oxygen, airway management, tube thoracostomy in the setting of pneumothoraces, mechanical ventilation (when required) with permissive hypercapnia, and judicious fluid administration are essential components in the management of blast lung injury.

Vacuum-Assisted, Constant-Force Exercise Device

NASA Technical Reports Server (NTRS)

Hansen, Christopher P.; Jensen, Scott

2006-01-01

The vacuum-assisted, constant-force exercise device (VAC-FED) has been proposed to fill a need for a safe, reliable exercise machine that would provide constant loads that could range from 20 to 250 lb (0.09 to 1.12 kN) with strokes that could range from 6 to 36 in. (0.15 to 0.91 m). The VAC-FED was originally intended to enable astronauts in microgravity to simulate the lifting of free weights, but it could just as well be used on Earth for simulated weight lifting and other constant-force exercises. Because the VAC-FED would utilize atmospheric/vacuum differential pressure instead of weights to generate force, it could weigh considerably less than either a set of free weights or a typical conventional exercise machine based on weights. Also, the use of atmospheric/ vacuum differential pressure to generate force would render the VAC-FED inherently safer, relative to free weights and to conventional exercise machines that utilize springs to generate forces. The overall function of the VAC-FED would be to generate a constant tensile force in an output cable, which would be attached to a bar, handle, or other exercise interface. The primary force generator in the VAC-FED would be a piston in a cylinder. The piston would separate a volume vented to atmosphere at one end of the cylinder from an evacuated volume at the other end of the cylinder (see figure). Hence, neglecting friction at the piston seals, the force generated would be nearly constant equal to the area of the piston multiplied by the atmospheric/vacuum differential pressure. In the vented volume in the cylinder, a direct-force cable would be looped around a pulley on the piston, doubling the stroke and halving the tension. One end of the direct-force cable would be anchored to a cylinder cap; the other end of the direct-force cable would be wrapped around a variable-ratio pulley that would couple tension to the output cable. As its name suggests, the variable-ratio pulley would contain a mechanism that

Two year operational experience with the TPS vacuum system

NASA Astrophysics Data System (ADS)

Yang, Y. C.; Chan, C. K.; Sheng, I. C.; Huang, I. T.; Y Chung, J.; Liang, C. C.

2017-07-01

The Taiwan Photon Source (TPS), a 3-GeV third generation synchrotron light source, was commissioned in 2014 December and is now currently operated in top-up mode at 300mA for users. During the past two years, the machine was completed to meet design goals with among others the installation of superconducting cavities (SRF), the installation of insertion devices (ID) and the correction of vacuum chamber structure downstream from the IDs. The design goal of 500mA beam current was achieved with a total accumulated beam dose of more than 1000Ah, resulting in three orders of magnitude reduction of out-gassing. As the beam current was increased, a few vacuum problems were encountered, including vacuum leaks, unexpected pressure bursts, etc. Vacuum related issues including high pressure events, lessons learned and operational experience will be presented and discussed in this paper.

Superconducting Vacuum-Gap Crossovers for High Performance Microwave Applications

NASA Technical Reports Server (NTRS)

Denis, Kevin L.; Brown, Ari D.; Chang, Meng-Ping; Hu, Ron; U-Yen, Kongpop; Wollack, Edward J.

2016-01-01

The design and fabrication of low-loss wide-bandwidth superconducting vacuum-gap crossovers for high performance millimeter wave applications are described. In order to reduce ohmic and parasitic losses at millimeter wavelengths a vacuum gap is preferred relative to dielectric spacer. Here, vacuum-gap crossovers were realized by using a sacrificial polymer layer followed by niobium sputter deposition optimized for coating coverage over an underlying niobium signal layer. Both coplanar waveguide and microstrip crossover topologies have been explored in detail. The resulting fabrication process is compatible with a bulk micro-machining process for realizing waveguide coupled detectors, which includes sacrificial wax bonding, and wafer backside deep reactive ion etching for creation of leg isolated silicon membrane structures. Release of the vacuum gap structures along with the wax bonded wafer after DRIE is implemented in the same process step used to complete the detector fabrication. ?

NOBLAST and JAMBLAST: New Options for BLAST and a Java Application Manager for BLAST results.

PubMed

Lagnel, Jacques; Tsigenopoulos, Costas S; Iliopoulos, Ioannis

2009-03-15

NOBLAST (New Options for BLAST) is an open source program that provides a new user-friendly tabular output format for various NCBI BLAST programs (Blastn, Blastp, Blastx, Tblastn, Tblastx, Mega BLAST and Psi BLAST) without any use of a parser and provides E-value correction in case of use of segmented BLAST database. JAMBLAST using the NOBLAST output allows the user to manage, view and filter the BLAST hits using a number of selection criteria. A distribution package of NOBLAST and JAMBLAST including detailed installation procedure is freely available from http://sourceforge.net/projects/JAMBLAST/ and http://sourceforge.net/projects/NOBLAST. Supplementary data are available at Bioinformatics online.

29 CFR 1926.909 - Firing the blast.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Firing the blast. (a) A code of blasting signals equivalent to Table U-1, shall be posted on one or more... blasts 5 minutes prior to blast signal. Blast Signal—A series of short blasts 1 minute prior to the shot...

29 CFR 1926.909 - Firing the blast.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Firing the blast. (a) A code of blasting signals equivalent to Table U-1, shall be posted on one or more... blasts 5 minutes prior to blast signal. Blast Signal—A series of short blasts 1 minute prior to the shot...

29 CFR 1926.909 - Firing the blast.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Firing the blast. (a) A code of blasting signals equivalent to Table U-1, shall be posted on one or more... blasts 5 minutes prior to blast signal. Blast Signal—A series of short blasts 1 minute prior to the shot...

29 CFR 1926.909 - Firing the blast.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Firing the blast. (a) A code of blasting signals equivalent to Table U-1, shall be posted on one or more... blasts 5 minutes prior to blast signal. Blast Signal—A series of short blasts 1 minute prior to the shot...

29 CFR 1926.909 - Firing the blast.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Firing the blast. (a) A code of blasting signals equivalent to Table U-1, shall be posted on one or more... blasts 5 minutes prior to blast signal. Blast Signal—A series of short blasts 1 minute prior to the shot...

Blast injury from explosive munitions.

PubMed

Cernak, I; Savic, J; Ignjatovic, D; Jevtic, M

1999-07-01

To evaluate the effect of blast in common war injuries. One thousand three hundred and three patients injured by explosive munitions and demonstrating extremity wounds without other penetrating injuries were admitted to the Military Medical Academy in Belgrade between 1991 and 1994. Of these, 665 patients (51%) had symptoms and physical signs that were compatible with the clinical diagnosis of primary blast injury, whereas the remaining 658 patients did not. Random sampling of 65 patients in the blast group during the early posttraumatic period showed statistically significant elevations in blood thromboxane A2 (TxA2), prostacyclin (PGI2), and sulfidopeptide leukotrienes compared with the random sample of 62 patients in the nonblast group. This difference could not be accounted for by differing injury severity between the groups, because the severity of wounds as measured by both the Injury Severity Score and the Red Cross Wound Classification was similar in both groups. Amongst blast patients, 200 patients (30%) had long-term (1 year) symptoms and signs reflecting central nervous system disorders. These symptoms and signs were only sporadically found in 4% of the nonblast patients. These findings indicate that primary blast injury is more common in war injuries than previously thought and that of those affected by blast, a surprisingly high proportion retain long-term neurologic disability. The elevation in eicosanoids could be used to confirm and monitor blast injury. In relation to the immediate management of patients injured by explosive weapons, it follows that particular attention should be paid to the presence and/or development of blast injury. Our findings indicate that blast is more common in war injuries than previously thought. Eicosanoid changes after blast injury suggest that blast injury causes a major physiologic stress. A variety of effects on the central nervous system suggest that blast injury could be responsible for some aspects of what is now

Divide and Conquer (DC) BLAST: fast and easy BLAST execution within HPC environments

DOE PAGES

Yim, Won Cheol; Cushman, John C.

2017-07-22

Bioinformatics is currently faced with very large-scale data sets that lead to computational jobs, especially sequence similarity searches, that can take absurdly long times to run. For example, the National Center for Biotechnology Information (NCBI) Basic Local Alignment Search Tool (BLAST and BLAST+) suite, which is by far the most widely used tool for rapid similarity searching among nucleic acid or amino acid sequences, is highly central processing unit (CPU) intensive. While the BLAST suite of programs perform searches very rapidly, they have the potential to be accelerated. In recent years, distributed computing environments have become more widely accessible andmore » used due to the increasing availability of high-performance computing (HPC) systems. Therefore, simple solutions for data parallelization are needed to expedite BLAST and other sequence analysis tools. However, existing software for parallel sequence similarity searches often requires extensive computational experience and skill on the part of the user. In order to accelerate BLAST and other sequence analysis tools, Divide and Conquer BLAST (DCBLAST) was developed to perform NCBI BLAST searches within a cluster, grid, or HPC environment by using a query sequence distribution approach. Scaling from one (1) to 256 CPU cores resulted in significant improvements in processing speed. Thus, DCBLAST dramatically accelerates the execution of BLAST searches using a simple, accessible, robust, and parallel approach. DCBLAST works across multiple nodes automatically and it overcomes the speed limitation of single-node BLAST programs. DCBLAST can be used on any HPC system, can take advantage of hundreds of nodes, and has no output limitations. Thus, this freely available tool simplifies distributed computation pipelines to facilitate the rapid discovery of sequence similarities between very large data sets.« less

Divide and Conquer (DC) BLAST: fast and easy BLAST execution within HPC environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yim, Won Cheol; Cushman, John C.

Bioinformatics is currently faced with very large-scale data sets that lead to computational jobs, especially sequence similarity searches, that can take absurdly long times to run. For example, the National Center for Biotechnology Information (NCBI) Basic Local Alignment Search Tool (BLAST and BLAST+) suite, which is by far the most widely used tool for rapid similarity searching among nucleic acid or amino acid sequences, is highly central processing unit (CPU) intensive. While the BLAST suite of programs perform searches very rapidly, they have the potential to be accelerated. In recent years, distributed computing environments have become more widely accessible andmore » used due to the increasing availability of high-performance computing (HPC) systems. Therefore, simple solutions for data parallelization are needed to expedite BLAST and other sequence analysis tools. However, existing software for parallel sequence similarity searches often requires extensive computational experience and skill on the part of the user. In order to accelerate BLAST and other sequence analysis tools, Divide and Conquer BLAST (DCBLAST) was developed to perform NCBI BLAST searches within a cluster, grid, or HPC environment by using a query sequence distribution approach. Scaling from one (1) to 256 CPU cores resulted in significant improvements in processing speed. Thus, DCBLAST dramatically accelerates the execution of BLAST searches using a simple, accessible, robust, and parallel approach. DCBLAST works across multiple nodes automatically and it overcomes the speed limitation of single-node BLAST programs. DCBLAST can be used on any HPC system, can take advantage of hundreds of nodes, and has no output limitations. Thus, this freely available tool simplifies distributed computation pipelines to facilitate the rapid discovery of sequence similarities between very large data sets.« less

Conditioning of the vacuum system of the TPS storage ring without baking in situ

NASA Astrophysics Data System (ADS)

Chan, C. K.; Chang, C. C.; Shueh, C.; Yang, I. C.; Wu, L. H.; Chen, B. Y.; Cheng, C. M.; Huang, Y. T.; Chuang, J. Y.; Cheng, Y. T.; Hsiao, Y. M.; Sheng, Albert

2017-04-01

To shorten the machine downtime, a maintenance procedure without baking in situ has been developed and applied to maintain and to upgrade the vacuum system of the TPS storage ring. The data of photon-stimulated desorption (PSD) reveal no obvious discrepancy between baking and not baking the vacuum system in situ. A beam-conditioning dose of extent only 11.8 A h is required to recover quickly the dynamic pressure of an unbaked vacuum system to its pre-intervention value according to the TPS maintenance experience.

The vacuum platform

NASA Astrophysics Data System (ADS)

McNab, A.

2017-10-01

This paper describes GridPP’s Vacuum Platform for managing virtual machines (VMs), which has been used to run production workloads for WLCG and other HEP experiments. The platform provides a uniform interface between VMs and the sites they run at, whether the site is organised as an Infrastructure-as-a-Service cloud system such as OpenStack, or an Infrastructure-as-a-Client system such as Vac. The paper describes our experience in using this platform, in developing and operating VM lifecycle managers Vac and Vcycle, and in interacting with VMs provided by LHCb, ATLAS, ALICE, CMS, and the GridPP DIRAC service to run production workloads.

Primary blast injuries.

PubMed

Phillips, Y Y

1986-12-01

Injury from explosion may be due to the direct cussive effect of the blast wave (primary), being struck by material propelled by the blast (secondary), to whole-body displacement and impact (tertiary), or to miscellaneous effects from burns, toxic acids, and so on. Severe primary blast injury is most likely to be seen in military operations but can occur in civilian industrial accidents or terrorist actions. Damage is seen almost exclusively in air-containing organs--the lungs, the gastrointestinal tract, and the auditory system. Pulmonary injury is characterized by pneumothorax, parenchymal hemorrhage, and alveolar rupture. The last is responsible for the arterial air embolism that is the principle cause of early mortality. Treatment for blast injury is similar to that for blunt trauma. The sequalae of air embolization to the cerebral or coronary circulation may be altered by immediate hyperbaric therapy. Use of positive pressure ventilatory systems should be closely monitored as they may increase the risk of air embolism in pneumothorax. Morbidity and mortality may be increased by strenuous exertion after injury and by the wearing of a cloth ballistic vest at the time of the blast.

Machine vision systems using machine learning for industrial product inspection

NASA Astrophysics Data System (ADS)

Lu, Yi; Chen, Tie Q.; Chen, Jie; Zhang, Jian; Tisler, Anthony

2002-02-01

Machine vision inspection requires efficient processing time and accurate results. In this paper, we present a machine vision inspection architecture, SMV (Smart Machine Vision). SMV decomposes a machine vision inspection problem into two stages, Learning Inspection Features (LIF), and On-Line Inspection (OLI). The LIF is designed to learn visual inspection features from design data and/or from inspection products. During the OLI stage, the inspection system uses the knowledge learnt by the LIF component to inspect the visual features of products. In this paper we will present two machine vision inspection systems developed under the SMV architecture for two different types of products, Printed Circuit Board (PCB) and Vacuum Florescent Displaying (VFD) boards. In the VFD board inspection system, the LIF component learns inspection features from a VFD board and its displaying patterns. In the PCB board inspection system, the LIF learns the inspection features from the CAD file of a PCB board. In both systems, the LIF component also incorporates interactive learning to make the inspection system more powerful and efficient. The VFD system has been deployed successfully in three different manufacturing companies and the PCB inspection system is the process of being deployed in a manufacturing plant.

A mouse model of ocular blast injury that induces closed globe anterior and posterior pole damage

PubMed Central

Hines-Beard, Jessica; Marchetta, Jeffrey; Gordon, Sarah; Chaum, Edward; Geisert, Eldon E.; Rex, Tonia S.

2012-01-01

We developed and characterized a mouse model of primary ocular blast injury. The device consists of: a pressurized air tank attached to a regulated paintball gun with a machined barrel; a chamber that protects the mouse from direct injury and recoil, while exposing the eye; and a secure platform that enables fine, controlled movement of the chamber in relation to the barrel. Expected pressures were calculated and the optimal pressure transducer, based on the predicted pressures, was positioned to measure output pressures at the location where the mouse eye would be placed. Mice were exposed to one of three blast pressures (23.6, 26.4, or 30.4psi). Gross pathology, intraocular pressure, optical coherence tomography, and visual acuity were assessed 0, 3, 7, 14, and 28 days after exposure. Contralateral eyes and non-blast exposed mice were used as controls. We detected increased damage with increased pressures and a shift in the damage profile over time. Gross pathology included corneal edema, corneal abrasions, and optic nerve avulsion. Retinal damage was detected by optical coherence tomography and a deficit in visual acuity was detected by optokinetics. Our findings are comparable to those identified in Veterans of the recent wars with closed eye injuries as a result of blast exposure. In summary, this is a relatively simple system that creates injuries with features similar to those seen in patients with ocular blast trauma. This is an important new model for testing the short-term and long-term spectrum of closed globe blast injuries and potential therapeutic interventions. PMID:22504073

Computer assisted blast design and assessment tools

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cameron, A.R.; Kleine, T.H.; Forsyth, W.W.

1995-12-31

In general the software required by a blast designer includes tools that graphically present blast designs (surface and underground), can analyze a design or predict its result, and can assess blasting results. As computers develop and computer literacy continues to rise the development of and use of such tools will spread. An example of the tools that are becoming available includes: Automatic blast pattern generation and underground ring design; blast design evaluation in terms of explosive distribution and detonation simulation; fragmentation prediction; blast vibration prediction and minimization; blast monitoring for assessment of dynamic performance; vibration measurement, display and signal processing;more » evaluation of blast results in terms of fragmentation; and risk and reliability based blast assessment. The authors have identified a set of criteria that are essential in choosing appropriate software blasting tools.« less

BLAST BIOLOGY. Technical Progress Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, C.S.; Richmond, D.R.

1959-09-18

Experimental data regarding the biologic consequences of exposure to several environmental variations associated with actual and simulated explosive detonations were reviewed. Blast biology is discussed relative to primary, secondary, tentiary, and miscellaneous blast effects as those attributable, respectively, to variations in environmental pressure, trauma from blast-produced missiles (both penetrating and nonpenetrating), the consequences of physical displacement of biological targets by blast-produced winds, and hazards due to ground shock, dust, and thermal phenomena not caused by thermal radiation per se. Primary blast effects were considered, noting physical-biophysical factors contributing to the observed pathophysiology. A simple hydrostatic model was utilized diagrammatically inmore » pointing out possible etiologic mechanisms. The gross biologic response to single. "fast"-rising overpressures were described as was the tolerance of mice, rats, guinea pigs. and rabbits to "long"-duration pressure pulses rising "rapidly" in single and double steps. Data regarding biological response to "slowly" rising over-pressures of "long" duration are discussed. Attention was called to the similarities under certain circumstances between thoracic trauma from nonpenetrating missiles and that noted from air blast. The association between air emboli, increase in lung weight (hemorrhage and edema), and mortality was discussed. Data relevant to the clinical symptoms and therapy of blast injury are presented. The relation of blast hazards to nuclear explosions was assessed and one approach to predicting the maximal potential casualties from blast phenomena is presented making use of arbitrary and tentative criteria. (auth)« less

Shock tubes and blast injury modeling.

PubMed

Ning, Ya-Lei; Zhou, Yuan-Guo

2015-01-01

Explosive blast injury has become the most prevalent injury in recent military conflicts and terrorist attacks. The magnitude of this kind of polytrauma is complex due to the basic physics of blast and the surrounding environments. Therefore, development of stable, reproducible and controllable animal model using an ideal blast simulation device is the key of blast injury research. The present review addresses the modeling of blast injury and applications of shock tubes.

Identification of blast resistance genes for managing rice blast disease

USDA-ARS?s Scientific Manuscript database

Rice blast, caused by the fungal pathogen Magnaporthe oryzae, is one of the most devastating diseases worldwide. In the present study, an international set of monogenic differentials carrying 24 major blast resistance (R) genes (Pia, Pib, Pii, Pik, Pik-h, Pik-m, Pik-p, Pik-s, Pish, Pit, Pita, Pita2,...

Milking performance evaluation and factors affecting milking claw vacuum levels with flow simulator.

PubMed

Enokidani, Masafumi; Kawai, Kazuhiro; Shinozuka, Yasunori; Watanabe, Aiko

2017-08-01

Milking performance of milking machines that matches the production capability of dairy cows is important in reducing the risk of mastitis, particularly in high-producing cows. This study used a simulated milking device to examine the milking performance of the milking system of 73 dairy farms and to analyze the factors affecting claw vacuum. Mean claw vacuum and range of fluctuation of claw vacuum (claw vacuum range) were measured at three different flow rates: 5.7, 7.6 and 8.7 kg/min. At the highest flow rate, only 16 farms (21.9%) met both standards of mean claw vacuum ≥35 kPa and claw vacuum range ≤ 7 kPa, showing that milking systems currently have poor milking performance. The factors affecting mean claw vacuum were claw type, milk-meter and vacuum shut-off device; the factor affecting claw vacuum range was claw type. Examination of the milking performance of the milking system using a simulated milking device allows an examination of the performance that can cope with high producing cows, indicating the possibility of reducing the risk of mastitis caused by inappropriate claw vacuum. © 2016 Japanese Society of Animal Science.

Modelling the Source of Blasting for the Numerical Simulation of Blast-Induced Ground Vibrations: A Review

NASA Astrophysics Data System (ADS)

Ainalis, Daniel; Kaufmann, Olivier; Tshibangu, Jean-Pierre; Verlinden, Olivier; Kouroussis, Georges

2017-01-01

The mining and construction industries have long been faced with considerable attention and criticism in regard to the effects of blasting. The generation of ground vibrations is one of the most significant factors associated with blasting and is becoming increasingly important as mining sites are now regularly located near urban areas. This is of concern to not only the operators of the mine but also residents. Mining sites are subjected to an inevitable compromise: a production blast is designed to fragment the utmost amount of rock possible; however, any increase in the blast can generate ground vibrations which can propagate great distances and cause structural damage or discomfort to residents in surrounding urban areas. To accurately predict the propagation of ground vibrations near these sensitive areas, the blasting process and surrounding environment must be characterised and understood. As an initial step, an accurate model of the source of blast-induced vibrations is required. This paper presents a comprehensive review of the approaches to model the blasting source in order to critically evaluate developments in the field. An overview of the blasting process and description of the various factors which influence the blast performance and subsequent ground vibrations are also presented. Several approaches to analytically model explosives are discussed. Ground vibration prediction methods focused on seed waveform and charge weight scaling techniques are presented. Finally, numerical simulations of the blasting source are discussed, including methods to estimate blasthole wall pressure time-history, and hydrodynamic codes.

Human Injury Criteria for Underwater Blasts

PubMed Central

Lance, Rachel M.; Capehart, Bruce; Kadro, Omar; Bass, Cameron R.

2015-01-01

Underwater blasts propagate further and injure more readily than equivalent air blasts. Development of effective personal protection and countermeasures, however, requires knowledge of the currently unknown human tolerance to underwater blast. Current guidelines for prevention of underwater blast injury are not based on any organized injury risk assessment, human data or experimental data. The goal of this study was to derive injury risk assessments for underwater blast using well-characterized human underwater blast exposures in the open literature. The human injury dataset was compiled using 34 case reports on underwater blast exposure to 475 personnel, dating as early as 1916. Using severity ratings, computational reconstructions of the blasts, and survival information from a final set of 262 human exposures, injury risk models were developed for both injury severity and risk of fatality as functions of blast impulse and blast peak overpressure. Based on these human data, we found that the 50% risk of fatality from underwater blast occurred at 302±16 kPa-ms impulse. Conservatively, there is a 20% risk of pulmonary injury at a kilometer from a 20 kg charge. From a clinical point of view, this new injury risk model emphasizes the large distances possible for potential pulmonary and gut injuries in water compared with air. This risk value is the first impulse-based fatality risk calculated from human data. The large-scale inconsistency between the blast exposures in the case reports and the guidelines available in the literature prior to this study further underscored the need for this new guideline derived from the unique dataset of actual injuries in this study. PMID:26606655

Blast-wave density measurements

NASA Astrophysics Data System (ADS)

Ritzel, D. V.

Applications of a densitometer to obtain time-resolved data on the total density in blast-wave flows are described. A beta-source (promethium-147) is separated by a gap from a scintillator and a photomultiplier tube (PMT). Attenuation of the radiation beam by the passing blast wave is due to the total density in the gap volume during the wave passage. Signal conditioning and filtering methods permit the system to output linearized data. Results are provided from use of the system to monitor blast waves emitted by detonation of a 10.7 m diameter fiberglass sphere containing 609 tons of ammonium nitrate/fuel oil at a 50.6 m height. Blast wave density data are provided for peak overpressure levels of 245, 172 and 70 kPa and distances of 183, 201 and 314 m from ground zero. Data resolution was of high enough quality to encourage efforts to discriminate dust and gasdynamic phenomena within passing blast waves.

Low-cost blast wave generator for studies of hearing loss and brain injury: blast wave effects in closed spaces.

PubMed

Newman, Andrew J; Hayes, Sarah H; Rao, Abhiram S; Allman, Brian L; Manohar, Senthilvelan; Ding, Dalian; Stolzberg, Daniel; Lobarinas, Edward; Mollendorf, Joseph C; Salvi, Richard

2015-03-15

Military personnel and civilians living in areas of armed conflict have increased risk of exposure to blast overpressures that can cause significant hearing loss and/or brain injury. The equipment used to simulate comparable blast overpressures in animal models within laboratory settings is typically very large and prohibitively expensive. To overcome the fiscal and space limitations introduced by previously reported blast wave generators, we developed a compact, low-cost blast wave generator to investigate the effects of blast exposures on the auditory system and brain. The blast wave generator was constructed largely from off the shelf components, and reliably produced blasts with peak sound pressures of up to 198dB SPL (159.3kPa) that were qualitatively similar to those produced from muzzle blasts or explosions. Exposure of adult rats to 3 blasts of 188dB peak SPL (50.4kPa) resulted in significant loss of cochlear hair cells, reduced outer hair cell function and a decrease in neurogenesis in the hippocampus. Existing blast wave generators are typically large, expensive, and are not commercially available. The blast wave generator reported here provides a low-cost method of generating blast waves in a typical laboratory setting. This compact blast wave generator provides scientists with a low cost device for investigating the biological mechanisms involved in blast wave injury to the rodent cochlea and brain that may model many of the damaging effects sustained by military personnel and civilians exposed to intense blasts. Copyright © 2015 Elsevier B.V. All rights reserved.

Low-Cost Blast Wave Generator for Studies of Hearing Loss and Brain Injury: Blast Wave Effects in Closed Spaces

PubMed Central

Newman, Andrew J.; Hayes, Sarah H.; Rao, Abhiram S.; Allman, Brian L.; Manohar, Senthilvelan; Ding, Dalian; Stolzberg, Daniel; Lobarinas, Edward; Mollendorf, Joseph C.; Salvi, Richard

2015-01-01

Background Military personnel and civilians living in areas of armed conflict have increased risk of exposure to blast overpressures that can cause significant hearing loss and/or brain injury. The equipment used to simulate comparable blast overpressures in animal models within laboratory settings is typically very large and prohibitively expensive. New Method To overcome the fiscal and space limitations introduced by previously reported blast wave generators, we developed a compact, low-cost blast wave generator to investigate the effects of blast exposures on the auditory system and brain. Results The blast wave generator was constructed largely from off the shelf components, and reliably produced blasts with peak sound pressures of up to 198 dB SPL (159.3 kPa) that were qualitatively similar to those produced from muzzle blasts or explosions. Exposure of adult rats to 3 blasts of 188 dB peak SPL (50.4 kPa) resulted in significant loss of cochlear hair cells, reduced outer hair cell function and a decrease in neurogenesis in the hippocampus. Comparison to existing methods Existing blast wave generators are typically large, expensive, and are not commercially available. The blast wave generator reported here provides a low-cost method of generating blast waves in a typical laboratory setting. Conclusions This compact blast wave generator provides scientists with a low cost device for investigating the biological mechanisms involved in blast wave injury to the rodent cochlea and brain that may model many of the damaging effects sustained by military personnel and civilians exposed to intense blasts. PMID:25597910

[Confined blasting in microexplosion cystolithotripsy].

PubMed

Uchida, M

1989-03-01

This paper is the 12th report in a series of studies on the application of microexplosion to medicine and biology. Microexplosion lithotripsy is a newly developed technique in our clinic to crush urinary stones with small quantities of explosives. A systematic research project has been performed since the first report of microexplosion lithotripsy in 1977. As a result, microexplosion was successfully applied to the destruction of bladder stones in 130 cases from 1981 to 1988. In blasting to crush rocks in industrial works, two kinds of blasting are available: external charge blasting and confined blasting. The detonation power of the latter is 10 to 50 times larger than that of the former. A detruction test using several kinds of spherical form model calculus and lead azide explosive was performed. The formula to calculate the suitable explosive dose was determined experimentally as shown below. (formula; see text) Thus the theory in general industrial blasting with massive explosives was proved to be effective also in microexplosion with small explosives. An original electric drill system was developed to make a hole in stones for confined blasting. 60 cases, including 2 cases of giant bladder stones over 100 g in weight, were successfully treated by confined blasting using this system without any complication. We consider that any bladder stones, however big or however many, can be treated by microexplosion lithotripsy with confined blasting.

Effect of Human and Sheep Lung Orientation on Primary Blast Injury Induced by Single Blast

DTIC Science & Technology

2010-09-01

may be injured by m ore than one of these mechanisms in any given event. Primary blast in juries ( PBI ) are exclusively caused by the blast...overpressure. A PBI usually affects air-containing organs such as t he lung, ears and gastrointestinal tract. Secon dary blast injuries are caused by...orientation on blast injuries predicted in human and sheep models. From th is study, it is predicted that the greatest reduction in lung PBI may be

Blast optimization for improved dragline productivity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Humphreys, M.; Baldwin, G.

1994-12-31

A project aimed at blast optimization for large open pit coal mines is utilizing blast monitoring and analysis techniques, advanced dragline monitoring equipment, and blast simulation software, to assess the major controlling factors affecting both blast performance and subsequent dragline productivity. This has involved collaborative work between the explosives supplier, mine operator, monitoring equipment manufacturer, and a mining research organization. The results from trial blasts and subsequently monitored dragline production have yielded promising results and continuing studies are being conducted as part of a blast optimization program. It should be stressed that the optimization of blasting practices for improved draglinemore » productivity is a site specific task, achieved through controlled and closely monitored procedures. The benefits achieved at one location can not be simply transferred to another minesite unless similar improvement strategies are first implemented.« less

Concussive brain injury from explosive blast

PubMed Central

de Lanerolle, Nihal C; Hamid, Hamada; Kulas, Joseph; Pan, Jullie W; Czlapinski, Rebecca; Rinaldi, Anthony; Ling, Geoffrey; Bandak, Faris A; Hetherington, Hoby P

2014-01-01

Objective Explosive blast mild traumatic brain injury (mTBI) is associated with a variety of symptoms including memory impairment and posttraumatic stress disorder (PTSD). Explosive shock waves can cause hippocampal injury in a large animal model. We recently reported a method for detecting brain injury in soldiers with explosive blast mTBI using magnetic resonance spectroscopic imaging (MRSI). This method is applied in the study of veterans exposed to blast. Methods The hippocampus of 25 veterans with explosive blast mTBI, 20 controls, and 12 subjects with PTSD but without exposure to explosive blast were studied using MRSI at 7 Tesla. Psychiatric and cognitive assessments were administered to characterize the neuropsychiatric deficits and compare with findings from MRSI. Results Significant reductions in the ratio of N-acetyl aspartate to choline (NAA/Ch) and N-acetyl aspartate to creatine (NAA/Cr) (P < 0.05) were found in the anterior portions of the hippocampus with explosive blast mTBI in comparison to control subjects and were more pronounced in the right hippocampus, which was 15% smaller in volume (P < 0.05). Decreased NAA/Ch and NAA/Cr were not influenced by comorbidities – PTSD, depression, or anxiety. Subjects with PTSD without blast had lesser injury, which tended to be in the posterior hippocampus. Explosive blast mTBI subjects had a reduction in visual memory compared to PTSD without blast. Interpretation The region of the hippocampus injured differentiates explosive blast mTBI from PTSD. MRSI is quite sensitive in detecting and localizing regions of neuronal injury from explosive blast associated with memory impairment. PMID:25493283

Fragment Size Distribution of Blasted Rock Mass

NASA Astrophysics Data System (ADS)

Jug, Jasmin; Strelec, Stjepan; Gazdek, Mario; Kavur, Boris

2017-12-01

Rock mass is a heterogeneous material, and the heterogeneity of rock causes sizes distribution of fragmented rocks in blasting. Prediction of blasted rock mass fragmentation has a significant role in the overall economics of opencast mines. Blasting as primary fragmentation can significantly decrease the cost of loading, transport, crushing and milling operations. Blast fragmentation chiefly depends on the specific blast design (geometry of blast holes drilling, the quantity and class of explosive, the blasting form, the timing and partition, etc.) and on the properties of the rock mass (including the uniaxial compressive strength, the rock mass elastic Young modulus, the rock discontinuity characteristics and the rock density). Prediction and processing of blasting results researchers can accomplish by a variety of existing software’s and models, one of them is the Kuz-Ram model, which is possibly the most widely used approach to estimating fragmentation from blasting. This paper shows the estimation of fragmentation using the "SB" program, which was created by the authors. Mentioned program includes the Kuz-Ram model. Models of fragmentation are confirmed and calibrated by comparing the estimated fragmentation with actual post-blast fragmentation from image processing techniques. In this study, the Kuz-Ram fragmentation model has been used for an open-pit limestone quarry in Dalmatia, southern Croatia. The resulting calibrated value of the rock factor enables the quality prognosis of fragmentation in further blasting works, with changed drilling geometry and blast design parameters. It also facilitates simulation in the program to optimize blasting works and get the desired fragmentations of the blasted rock mass.

NCBI BLAST+ integrated into Galaxy.

PubMed

Cock, Peter J A; Chilton, John M; Grüning, Björn; Johnson, James E; Soranzo, Nicola

2015-01-01

The NCBI BLAST suite has become ubiquitous in modern molecular biology and is used for small tasks such as checking capillary sequencing results of single PCR products, genome annotation or even larger scale pan-genome analyses. For early adopters of the Galaxy web-based biomedical data analysis platform, integrating BLAST into Galaxy was a natural step for sequence comparison workflows. The command line NCBI BLAST+ tool suite was wrapped for use within Galaxy. Appropriate datatypes were defined as needed. The integration of the BLAST+ tool suite into Galaxy has the goal of making common BLAST tasks easy and advanced tasks possible. This project is an informal international collaborative effort, and is deployed and used on Galaxy servers worldwide. Several examples of applications are described here.

27 CFR 555.220 - Table of separation distances of ammonium nitrate and blasting agents from explosives or blasting...

Code of Federal Regulations, 2010 CFR

2010-04-01

... distances of ammonium nitrate and blasting agents from explosives or blasting agents. 555.220 Section 555... ammonium nitrate and blasting agents from explosives or blasting agents. Table: Department of Defense... Not over Minimum separation distance of acceptor from donor when barricaded (ft.) Ammonium nitrate...

27 CFR 555.220 - Table of separation distances of ammonium nitrate and blasting agents from explosives or blasting...

Code of Federal Regulations, 2011 CFR

2011-04-01

... distances of ammonium nitrate and blasting agents from explosives or blasting agents. 555.220 Section 555... ammonium nitrate and blasting agents from explosives or blasting agents. Table: Department of Defense... Not over Minimum separation distance of acceptor from donor when barricaded (ft.) Ammonium nitrate...

27 CFR 555.220 - Table of separation distances of ammonium nitrate and blasting agents from explosives or blasting...

Code of Federal Regulations, 2012 CFR

2012-04-01

... distances of ammonium nitrate and blasting agents from explosives or blasting agents. 555.220 Section 555... ammonium nitrate and blasting agents from explosives or blasting agents. Table: Department of Defense... Not over Minimum separation distance of acceptor from donor when barricaded (ft.) Ammonium nitrate...

27 CFR 555.220 - Table of separation distances of ammonium nitrate and blasting agents from explosives or blasting...

Code of Federal Regulations, 2013 CFR

2013-04-01

... distances of ammonium nitrate and blasting agents from explosives or blasting agents. 555.220 Section 555... ammonium nitrate and blasting agents from explosives or blasting agents. Table: Department of Defense... Not over Minimum separation distance of acceptor from donor when barricaded (ft.) Ammonium nitrate...

27 CFR 555.220 - Table of separation distances of ammonium nitrate and blasting agents from explosives or blasting...

Code of Federal Regulations, 2014 CFR

2014-04-01

... distances of ammonium nitrate and blasting agents from explosives or blasting agents. 555.220 Section 555... ammonium nitrate and blasting agents from explosives or blasting agents. Table: Department of Defense... Not over Minimum separation distance of acceptor from donor when barricaded (ft.) Ammonium nitrate...

Computational modeling of human head under blast in confined and open spaces: primary blast injury.

PubMed

Rezaei, A; Salimi Jazi, M; Karami, G

2014-01-01

In this paper, a computational modeling for biomechanical analysis of primary blast injuries is presented. The responses of the brain in terms of mechanical parameters under different blast spaces including open, semi-confined, and confined environments are studied. In the study, the effect of direct and indirect blast waves from the neighboring walls in the confined environments will be taken into consideration. A 50th percentile finite element head model is exposed to blast waves of different intensities. In the open space, the head experiences a sudden intracranial pressure (ICP) change, which vanishes in a matter of a few milliseconds. The situation is similar in semi-confined space, but in the confined space, the reflections from the walls will create a number of subsequent peaks in ICP with a longer duration. The analysis procedure is based on a simultaneous interaction simulation of the deformable head and its components with the blast wave propagations. It is concluded that compared with the open and semi-confined space settings, the walls in the confined space scenario enhance the risk of primary blast injuries considerably because of indirect blast waves transferring a larger amount of damaging energy to the head. Copyright © 2013 John Wiley & Sons, Ltd.

Distinguishing Realistic Military Blasts from Firecrackers in Mitigation Studies of Blast Induced Traumatic Brain Injury

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moss, W C; King, M J; Blackman, E G

In their Contributed Article, Nyein et al. (1,2) present numerical simulations of blast waves interacting with a helmeted head and conclude that a face shield may significantly mitigate blast induced traumatic brain injury (TBI). A face shield may indeed be important for future military helmets, but the authors derive their conclusions from a much smaller explosion than typically experienced on the battlefield. The blast from the 3.16 gm TNT charge of (1) has the following approximate peak overpressures, positive phase durations, and incident impulses (3): 10 atm, 0.25 ms, and 3.9 psi-ms at the front of the head (14 cmmore » from charge), and 1.4 atm, 0.32 ms, and 1.7 psi-ms at the back of a typical 20 cm head (34 cm from charge). The peak pressure of the wave decreases by a factor of 7 as it traverses the head. The blast conditions are at the threshold for injury at the front of the head, but well below threshold at the back of the head (4). The blast traverses the head in 0.3 ms, roughly equal to the positive phase duration of the blast. Therefore, when the blast reaches the back of the head, near ambient conditions exist at the front. Because the headform is so close to the charge, it experiences a wave with significant curvature. By contrast, a realistic blast from a 2.2 kg TNT charge ({approx} an uncased 105 mm artillery round) is fatal at an overpressure of 10 atm (4). For an injury level (4) similar to (1), a 2.2 kg charge has the following approximate peak overpressures, positive phase durations, and incident impulses (3): 2.1 atm, 2.3 ms, and 18 psi-ms at the front of the head (250 cm from charge), and 1.8 atm, 2.5 ms, and 16.8 psi-ms at the back of the head (270 cm from charge). The peak pressure decreases by only a factor of 1.2 as it traverses the head. Because the 0.36 ms traversal time is much smaller than the positive phase duration, pressures on the head become relatively uniform when the blast reaches the back of the head. The larger standoff

Comment on "chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model".

PubMed

Tsao, Jack W

2012-10-24

In their recent paper, Goldstein et al. show murine brain tau neuropathology after explosive blast with head rotation but do not present additional evidence that would delineate whether this neuropathology was principally caused by blast exposure alone or by blast exposure plus head rotational injury.

Lightweight blast shield

DOEpatents

Mixon, Larry C.; Snyder, George W.; Hill, Scott D.; Johnson, Gregory L.; Wlodarski, J. Frank; von Spakovsky, Alexis P.; Emerson, John D.; Cole, James M.; Tipton, John P.

1991-01-01

A tandem warhead missile arrangement that has a composite material housing structure with a first warhead mounted at one end and a second warhead mounted near another end of the composite structure with a dome shaped composite material blast shield mounted between the warheads to protect the second warhead from the blast of the first warhead.

Automated real-time detection of defects during machining of ceramics

DOEpatents

Ellingson, William A.; Sun, Jiangang

1997-01-01

Apparatus for the automated real-time detection and classification of defects during the machining of ceramic components employs an elastic optical scattering technique using polarized laser light. A ceramic specimen is continuously moved while being machined. Polarized laser light is directed onto the ceramic specimen surface at a fixed position just aft of the machining tool for examination of the newly machined surface. Any foreign material near the location of the laser light on the ceramic specimen is cleared by an air blast. As the specimen is moved, its surface is continuously scanned by the polarized laser light beam to provide a two-dimensional image presented in real-time on a video display unit, with the motion of the ceramic specimen synchronized with the data acquisition speed. By storing known "feature masks" representing various surface and sub-surface defects and comparing measured defects with the stored feature masks, detected defects may be automatically characterized. Using multiple detectors, various types of defects may be detected and classified.

Cerebrovascular Injury in Blast Loading

DTIC Science & Technology

2010-01-01

TITLE: Cerebrovascular injury in blast loading PRINCIPAL INVESTIGATOR: Kenneth L. Monson, PhD...SUBTITLE Cerebrovascular injury in blast loading 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-08-1-0295 5c. PROGRAM ELEMENT NUMBER 6...and pH control. 15. SUBJECT TERMS Blast brain injury; cerebrovascular injury and dysfunction; shock tube 16. SECURITY CLASSIFICATION OF: 17

30 CFR 780.13 - Operation plan: Blasting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Operation plan: Blasting. 780.13 Section 780.13... SURFACE MINING PERMIT APPLICATIONS-MINIMUM REQUIREMENTS FOR RECLAMATION AND OPERATION PLAN § 780.13 Operation plan: Blasting. (a) Blasting plan. Each application shall contain a blasting plan for the proposed...

Nuclear Air Blast Effects.

DTIC Science & Technology

1982-06-01

AD-All? 43 SCIENCE APPLICATZOhu INC NCLAA VA F/6 19/4I NUICLEAR AIR BLAST IFPCTS(U) JUR " PRY UNCLASSIFID SAI-63-636-VA NLOOI I-C lit? I. 1174~ 132...SiCuftIt, CLASSFICA?1lOw OF fl.IS PAQ-C( fhbl Dal. Lnt.,.d, REPORT DOCUMENTATION4 PAGE apoI ct~ NUCLEAR AIR BLAST EFFECTS FINAL REPORT SAI-83-836-WA...TUCSON a WASHINGTON NUCLEAR AIR BLAST EFFECTS FINAL REPORT SAI-83-836-WA Submitted to: Laboratory for Computational Physics Naval Research Laboratory

Machinability of Minor Wooden Species before and after Modification with Thermo-Vacuum Technology

PubMed Central

Sandak, Jakub; Goli, Giacomo; Cetera, Paola; Sandak, Anna; Cavalli, Alberto; Todaro, Luigi

2017-01-01

The influence of the thermal modification process on wood machinability was investigated with four minor species of low economic importance. A set of representative experimental samples was machined to the form of disks with sharp and dull tools. The resulting surface quality was visually evaluated by a team of experts according to the American standard procedure ASTM D-1666-87. The objective quantification of the surface quality was also done by means of a three dimensions (3D) surface scanner for the whole range of grain orientations. Visual assessment and 3D surface analysis showed a good agreement in terms of conclusions. The best quality of the wood surface was obtained when machining thermally modified samples. The positive effect of the material modification was apparent when cutting deodar cedar, black pine and black poplar in unfavorable conditions (i.e., against the grain). The difference was much smaller for an easy-machinability specie such as Italian alder. The use of dull tools resulted in the worst surface quality. Thermal modification has shown a very positive effect when machining with dull tools, leading to a relevant increment of the final surface smoothness. PMID:28772480

Machinability of Minor Wooden Species before and after Modification with Thermo-Vacuum Technology.

PubMed

Sandak, Jakub; Goli, Giacomo; Cetera, Paola; Sandak, Anna; Cavalli, Alberto; Todaro, Luigi

2017-01-28

The influence of the thermal modification process on wood machinability was investigated with four minor species of low economic importance. A set of representative experimental samples was machined to the form of disks with sharp and dull tools. The resulting surface quality was visually evaluated by a team of experts according to the American standard procedure ASTM D-1666-87. The objective quantification of the surface quality was also done by means of a three dimensions (3D) surface scanner for the whole range of grain orientations. Visual assessment and 3D surface analysis showed a good agreement in terms of conclusions. The best quality of the wood surface was obtained when machining thermally modified samples. The positive effect of the material modification was apparent when cutting deodar cedar, black pine and black poplar in unfavorable conditions (i.e., against the grain). The difference was much smaller for an easy-machinability specie such as Italian alder. The use of dull tools resulted in the worst surface quality. Thermal modification has shown a very positive effect when machining with dull tools, leading to a relevant increment of the final surface smoothness.

Very-Low-Cost, Rugged Vacuum System

NASA Technical Reports Server (NTRS)

Kline-Schoder, Robert; Sorensen, Paul; Passow, Christian; Bilski, Steve

2013-01-01

NASA, DoD, DHS, and commercial industry have a need for miniaturized, rugged, low-cost vacuum systems. Recent advances in sensor technology have led to the development of very small mass spectrometer detectors as well as other miniature analytical instruments. However, the vacuum systems to support these sensors remain large, heavy, and power-hungry. To meet this need, a miniaturized vacuum system was created based on a very small, rugged, and inexpensive- to-manufacture molecular drag pump (MDP). The MDP is enabled by the development of a miniature, veryhigh- speed, rugged, low-power, brushless DC motor optimized for wide temperature operation and long life. Such a pump represents an order-of-magnitude reduction in mass, volume, and cost over current, commercially available, state-ofthe- art vacuum pumps. The vacuum system consists of the MDP coupled to a ruggedized rough pump (for terrestrial applications or for planets with substantial atmospheres). The rotor in the MDP consists of a simple smooth cylinder of aluminum spinning at approximately 200,000 RPM inside an outer stator housing. The pump stator comprises a cylindrical aluminum housing with one or more specially designed grooves that serve as flow channels. To minimize the length of the pump, the gas is forced down the flow channels of the outer stator to the base of the pump. The gas is then turned and pulled toward the top through a second set of channels cut into an inner stator housing that surrounds the motor. The compressed gas then flows down channels in the motor housing to the exhaust port of the pump. The exhaust port of the pump is connected to a diaphragm or scroll pump. This pump delivers very high performance in a very small envelope. The design was simplified so that a smaller compression ratio, easier manufacturing process, and enhanced ruggedness can be achieved at the lowest possible cost. The machining of the rotor and stators is very simple compared to that necessary to fabricate TMP

Color changing photonic crystals detect blast exposure

PubMed Central

Cullen, D. Kacy; Xu, Yongan; Reneer, Dexter V.; Browne, Kevin D.; Geddes, James W.; Yang, Shu; Smith, Douglas H.

2010-01-01

Blast-induced traumatic brain injury (bTBI) is the “signature wound” of the current wars in Iraq and Afghanistan. However, with no objective information of relative blast exposure, warfighters with bTBI may not receive appropriate medical care and are at risk of being returned to the battlefield. Accordingly, we have created a colorimetric blast injury dosimeter (BID) that exploits material failure of photonic crystals to detect blast exposure. Appearing like a colored sticker, the BID is fabricated in photosensitive polymers via multi-beam interference lithography. Although very stable in the presence of heat, cold or physical impact, sculpted micro- and nano-structures of the BID are physically altered in a precise manner by blast exposure, resulting in color changes that correspond with blast intensity. This approach offers a lightweight, power-free sensor that can be readily interpreted by the naked eye. Importantly, with future refinement this technology may be deployed to identify soldiers exposed to blast at levels suggested to be supra-threshold for non-impact blast-induced mild TBI. PMID:21040795

Blast waves and how they interact with structures.

PubMed

Cullis, I G

2001-02-01

The paper defines and describes blast waves, their interaction with a structure and its subsequent response. Explosions generate blast waves, which need not be due to explosives. A blast wave consists of two parts: a shock wave and a blast wind. The paper explains how shock waves are formed and their basic properties. The physics of blast waves is non-linear and therefore non-intuitive. To understand how an explosion generates a blast wave a numerical modelling computer code, called a hydrocode has to be employed. This is briefly explained and the cAst Eulerian hydrocode is used to illustrate the formation and propagation of the blast wave generated by a 1 kg sphere of TNT explosive detonated 1 m above the ground. The paper concludes with a discussion of the response of a structure to a blast wave and shows that this response is governed by the structures natural frequency of vibration compared to the duration of the blast wave. The basic concepts introduced are illustrated in a second simulation that introduces two structures into the blast field of the TNT charge.

Army Blast Claims Evaluation Procedures

DTIC Science & Technology

1994-03-01

ARMY RESEARCH LABORATORY ARL-MR-131 Army Blast Claims Evaluation Procedures William P. Wright APPROVED FOR PUBUC RELEASE; DISTRIBtmON IS...NUMBERS Anny Blast Claims Evaluation Procedures 4G061-304-U2 6. AUTHOR(S) William P. Wrisht 1. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8...of the technical review process which bas been instituted to develop an opinion as to Army responsibility. 14. SUBJECT TERMS blast effects. muzzle

7 CFR 3201.78 - Blast media.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 15 2013-01-01 2013-01-01 false Blast media. 3201.78 Section 3201.78 Agriculture... Items § 3201.78 Blast media. (a) Definition. Abrasive particles sprayed forcefully to clean, remove... qualifying biobased blast media. By that date, Federal agencies that have the responsibility for drafting or...

7 CFR 3201.78 - Blast media.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false Blast media. 3201.78 Section 3201.78 Agriculture... Items § 3201.78 Blast media. (a) Definition. Abrasive particles sprayed forcefully to clean, remove... qualifying biobased blast media. By that date, Federal agencies that have the responsibility for drafting or...

Innovative Vacuum Distillation for Magnesium Recycling

NASA Astrophysics Data System (ADS)

Zhu, Tianbai; Li, Naiyi; Mei, Xiaoming; Yu, Alfred; Shang, Shixiang

Magnesium recycling now becomes a very important subject as magnesium consumption increases fast around the world. All commonly used magnesium die-casting alloys can be recycled and recovered to the primary metal quality. The recycled materials may be comprised of biscuits, sprues, runners, flash, overflows, dross, sludge, scrap parts, and old parts that are returned from service, An innovative magnesium recycle method, vacuum distillation, is developed and proved out to be able to recycle magnesium scraps, especially machining chips, oily magnesium, smelting sludge, dross or the mixture. With this process at a specific temperature and environment condition, magnesium in scraps can be gasified and then solidified to become crystal magnesium crown. This `recycled' magnesium crown is collected and used as the raw material of magnesium alloys. The experimental results show the vacuum distillation is a feasible and plausible method to recycle magnesium. Further, the cost analysis will be addressed in this paper.

Rodent model of direct cranial blast injury.

PubMed

Kuehn, Reed; Simard, Philippe F; Driscoll, Ian; Keledjian, Kaspar; Ivanova, Svetlana; Tosun, Cigdem; Williams, Alicia; Bochicchio, Grant; Gerzanich, Volodymyr; Simard, J Marc

2011-10-01

Traumatic brain injury resulting from an explosive blast is one of the most serious wounds suffered by warfighters, yet the effects of explosive blast overpressure directly impacting the head are poorly understood. We developed a rodent model of direct cranial blast injury (dcBI), in which a blast overpressure could be delivered exclusively to the head, precluding indirect brain injury via thoracic transmission of the blast wave. We constructed and validated a Cranium Only Blast Injury Apparatus (COBIA) to deliver blast overpressures generated by detonating .22 caliber cartridges of smokeless powder. Blast waveforms generated by COBIA replicated those recorded within armored vehicles penetrated by munitions. Lethal dcBI (LD(50) ∼ 515 kPa) was associated with: (1) apparent brainstem failure, characterized by immediate opisthotonus and apnea leading to cardiac arrest that could not be overcome by cardiopulmonary resuscitation; (2) widespread subarachnoid hemorrhages without cortical contusions or intracerebral or intraventricular hemorrhages; and (3) no pulmonary abnormalities. Sub-lethal dcBI was associated with: (1) apnea lasting up to 15 sec, with transient abnormalities in oxygen saturation; (2) very few delayed deaths; (3) subarachnoid hemorrhages, especially in the path of the blast wave; (4) abnormal immunolabeling for IgG, cleaved caspase-3, and β-amyloid precursor protein (β-APP), and staining for Fluoro-Jade C, all in deep brain regions away from the subarachnoid hemorrhages, but in the path of the blast wave; and (5) abnormalities on the accelerating Rotarod that persisted for the 1 week period of observation. We conclude that exposure of the head alone to severe explosive blast predisposes to significant neurological dysfunction.

Neurological Effects of Blast Injury

PubMed Central

Hicks, Ramona R.; Fertig, Stephanie J.; Desrocher, Rebecca E.; Koroshetz, Walter J.; Pancrazio, Joseph J.

2010-01-01

Over the last few years, thousands of soldiers and an even greater number of civilians have suffered traumatic injuries due to blast exposure, largely attributed to improvised explosive devices in terrorist and insurgent activities. The use of body armor is allowing soldiers to survive blasts that would otherwise be fatal due to systemic damage. Emerging evidence suggests that exposure to a blast can produce neurological consequences in the brain, but much remains unknown. To elucidate the current scientific basis for understanding blast-induced traumatic brain injury (bTBI), the NIH convened a workshop in April, 2008. A multidisciplinary group of neuroscientists, engineers, and clinicians were invited to share insights on bTBI, specifically pertaining to: physics of blast explosions, acute clinical observations and treatments, preclinical and computational models, and lessons from the international community on civilian exposures. This report provides an overview of the state of scientific knowledge of bTBI, drawing from the published literature, as well as presentations, discussions, and recommendations from the workshop. One of the major recommendations from the workshop was the need to characterize the effects of blast exposure on clinical neuropathology. Clearer understanding of the human neuropathology would enable validation of preclinical and computational models, which are attempting to simulate blast wave interactions with the central nervous system. Furthermore, the civilian experience with bTBI suggests that polytrauma models incorporating both brain and lung injuries may be more relevant to the study of civilian countermeasures than considering models with a neurological focus alone. PMID:20453776

Innovative Composite Structure Design for Blast Protection

DTIC Science & Technology

2007-01-01

2007-01-0483 Innovative Composite Structure Design for Blast Protection Dongying Jiang, Yuanyuan Liu MKP Structural Design Associates, Inc...protect vehicle and occupants against various explosives. The multi-level and multi-scenario blast simulation and design system integrates three major...numerical simulation of a BTR composite under a blast event. The developed blast simulation and design system will enable the prediction, design, and

Breeding for blast-disease-resistant and high-yield Thai jasmine rice (Oryza sativa L. cv. KDML 105) mutants using low-energy ion beams

NASA Astrophysics Data System (ADS)

Mahadtanapuk, S.; Teraarusiri, W.; Phanchaisri, B.; Yu, L. D.; Anuntalabhochai, S.

2013-07-01

Low-energy ion beam was applied on mutation induction for plant breeding of blast-disease-resistant Thai jasmine rice (Oryza sativa L. cv. KDML 105). Seeds of the wild-type rice were bombarded in vacuum by nitrogen ion beam at energy of 60-80 keV to a beam fluence range of 2 × 1016-2 × 1017 ions/cm2. The ion-bombarded rice seeds were grown in soil for 2 weeks as transplanted rice in plastic pots at 1 seedling/pot. The seedlings were then screened for blast resistance by Pyricularia grisea inoculation with 106 spores/ml concentrations. The blast-resistant rice mutant was planted up to F6 generation with the consistent phenotypic variation. The high percentage of the blast-disease-resistant rice was analyzed with DNA fingerprint. The HAT-RAPD (high annealing temperature-random amplified polymorphic DNA) marker revealed the modified polymorphism fragment presenting in the mutant compared with wild type (KDML 105). The cDNA fingerprints were investigated and the polymorphism fragment was subcloned into pGEM-T easy vector and then sequenced. The sequence of this fragment was compared with those already contained in the database, and the fragment was found to be related to the Spotted leaf protein 11 (Spl11).

Brain Vulnerability to Repeated Blast Overpressure and Polytrauma

DTIC Science & Technology

2015-10-01

characterization of the mouse model of repeated blast also found no cumula- tive effect of repeated blast on cortical levels of reactive oxygen species [39]. C...overpressure in rats to investigate the cumulative effects of multiple blast exposures on neurologic status, neurobehavioral function, and brain...preclinical model of blast overpressure in rats to investigate the cumulative effects of multiple blast exposures using neurological, neurochemical

Ultra Safe And Secure Blasting System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hart, M M

2009-07-27

The Ultra is a blasting system that is designed for special applications where the risk and consequences of unauthorized demolition or blasting are so great that the use of an extraordinarily safe and secure blasting system is justified. Such a blasting system would be connected and logically welded together through digital code-linking as part of the blasting system set-up and initialization process. The Ultra's security is so robust that it will defeat the people who designed and built the components in any attempt at unauthorized detonation. Anyone attempting to gain unauthorized control of the system by substituting components or tappingmore » into communications lines will be thwarted in their inability to provide encrypted authentication. Authentication occurs through the use of codes that are generated by the system during initialization code-linking and the codes remain unknown to anyone, including the authorized operator. Once code-linked, a closed system has been created. The system requires all components connected as they were during initialization as well as a unique code entered by the operator for function and blasting.« less

Vacuum force

NASA Astrophysics Data System (ADS)

Han, Yongquan

2015-03-01

To study on vacuum force, we must clear what is vacuum, vacuum is a space do not have any air and also ray. There is not exist an absolute the vacuum of space. The vacuum of space is relative, so that the vacuum force is relative. There is a certain that vacuum vacuum space exists. In fact, the vacuum space is relative, if the two spaces compared to the existence of relative vacuum, there must exist a vacuum force, and the direction of the vacuum force point to the vacuum region. Any object rotates and radiates. Rotate bend radiate- centripetal, gravity produced, relative gravity; non gravity is the vacuum force. Gravity is centripetal, is a trend that the objects who attracted wants to Centripetal, or have been do Centripetal movement. Any object moves, so gravity makes the object curve movement, that is to say, the radiation range curve movement must be in the gravitational objects, gravity must be existed in non vacuum region, and make the object who is in the region of do curve movement (for example: The earth moves around the sun), or final attracted in the form gravitational objects, and keep relatively static with attract object. (for example: objects on the earth moves but can't reach the first cosmic speed).

WImpiBLAST: web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing.

PubMed

Sharma, Parichit; Mantri, Shrikant S

2014-01-01

The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC) clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI) are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture, explain design

WImpiBLAST: Web Interface for mpiBLAST to Help Biologists Perform Large-Scale Annotation Using High Performance Computing

PubMed Central

Sharma, Parichit; Mantri, Shrikant S.

2014-01-01

The function of a newly sequenced gene can be discovered by determining its sequence homology with known proteins. BLAST is the most extensively used sequence analysis program for sequence similarity search in large databases of sequences. With the advent of next generation sequencing technologies it has now become possible to study genes and their expression at a genome-wide scale through RNA-seq and metagenome sequencing experiments. Functional annotation of all the genes is done by sequence similarity search against multiple protein databases. This annotation task is computationally very intensive and can take days to obtain complete results. The program mpiBLAST, an open-source parallelization of BLAST that achieves superlinear speedup, can be used to accelerate large-scale annotation by using supercomputers and high performance computing (HPC) clusters. Although many parallel bioinformatics applications using the Message Passing Interface (MPI) are available in the public domain, researchers are reluctant to use them due to lack of expertise in the Linux command line and relevant programming experience. With these limitations, it becomes difficult for biologists to use mpiBLAST for accelerating annotation. No web interface is available in the open-source domain for mpiBLAST. We have developed WImpiBLAST, a user-friendly open-source web interface for parallel BLAST searches. It is implemented in Struts 1.3 using a Java backbone and runs atop the open-source Apache Tomcat Server. WImpiBLAST supports script creation and job submission features and also provides a robust job management interface for system administrators. It combines script creation and modification features with job monitoring and management through the Torque resource manager on a Linux-based HPC cluster. Use case information highlights the acceleration of annotation analysis achieved by using WImpiBLAST. Here, we describe the WImpiBLAST web interface features and architecture, explain design

Experimental investigation of blast mitigation and particle-blast interaction during the explosive dispersal of particles and liquids

NASA Astrophysics Data System (ADS)

Pontalier, Q.; Loiseau, J.; Goroshin, S.; Frost, D. L.

2018-05-01

The attenuation of a blast wave from a high-explosive charge surrounded by a layer of inert material is investigated experimentally in a spherical geometry for a wide range of materials. The blast wave pressure is inferred from extracting the blast wave velocity with high-speed video as well as direct measurements with pressure transducers. The mitigant consists of either a packed bed of particles, a particle bed saturated with water, or a homogeneous liquid. The reduction in peak blast wave overpressure is primarily dependent on the mitigant to explosive mass ratio, M/ C, with the mitigant material properties playing a secondary role. Relative peak pressure mitigation reduces with distance and for low values of M/ C (< 10) can return to unmitigated pressure levels in the mid-to-far field. Solid particles are more effective at mitigating the blast overpressure than liquids, particularly in the near field and at low values of M/ C, suggesting that the energy dissipation during compaction, deformation, and fracture of the powders plays an important role. The difference in scaled arrival time of the blast and material fronts increases with M/ C and scaled distance, with solid particles giving the largest separation between the blast wave and cloud of particles. Surrounding a high-explosive charge with a layer of particles reduces the positive-phase blast impulse, whereas a liquid layer has no influence on the impulse in the far field. Taking the total impulse due to the blast wave and material impact into account implies that the damage to a nearby structure may actually be augmented for a range of distances. These results should be taken into consideration in the design of explosive mitigant systems.

Experimental investigation of blast mitigation and particle-blast interaction during the explosive dispersal of particles and liquids

NASA Astrophysics Data System (ADS)

Pontalier, Q.; Loiseau, J.; Goroshin, S.; Frost, D. L.

2018-04-01

The attenuation of a blast wave from a high-explosive charge surrounded by a layer of inert material is investigated experimentally in a spherical geometry for a wide range of materials. The blast wave pressure is inferred from extracting the blast wave velocity with high-speed video as well as direct measurements with pressure transducers. The mitigant consists of either a packed bed of particles, a particle bed saturated with water, or a homogeneous liquid. The reduction in peak blast wave overpressure is primarily dependent on the mitigant to explosive mass ratio, M/C, with the mitigant material properties playing a secondary role. Relative peak pressure mitigation reduces with distance and for low values of M/C (< 10) can return to unmitigated pressure levels in the mid-to-far field. Solid particles are more effective at mitigating the blast overpressure than liquids, particularly in the near field and at low values of M/C, suggesting that the energy dissipation during compaction, deformation, and fracture of the powders plays an important role. The difference in scaled arrival time of the blast and material fronts increases with M/C and scaled distance, with solid particles giving the largest separation between the blast wave and cloud of particles. Surrounding a high-explosive charge with a layer of particles reduces the positive-phase blast impulse, whereas a liquid layer has no influence on the impulse in the far field. Taking the total impulse due to the blast wave and material impact into account implies that the damage to a nearby structure may actually be augmented for a range of distances. These results should be taken into consideration in the design of explosive mitigant systems.

Porcine head response to blast.

PubMed

Shridharani, Jay K; Wood, Garrett W; Panzer, Matthew B; Capehart, Bruce P; Nyein, Michelle K; Radovitzky, Raul A; Bass, Cameron R 'dale'

2012-01-01

Recent studies have shown an increase in the frequency of traumatic brain injuries related to blast exposure. However, the mechanisms that cause blast neurotrauma are unknown. Blast neurotrauma research using computational models has been one method to elucidate that response of the brain in blast, and to identify possible mechanical correlates of injury. However, model validation against experimental data is required to ensure that the model output is representative of in vivo biomechanical response. This study exposes porcine subjects to primary blast overpressures generated using a compressed-gas shock tube. Shock tube blasts were directed to the unprotected head of each animal while the lungs and thorax were protected using ballistic protective vests similar to those employed in theater. The test conditions ranged from 110 to 740 kPa peak incident overpressure with scaled durations from 1.3 to 6.9 ms and correspond approximately with a 50% injury risk for brain bleeding and apnea in a ferret model scaled to porcine exposure. Instrumentation was placed on the porcine head to measure bulk acceleration, pressure at the surface of the head, and pressure inside the cranial cavity. Immediately after the blast, 5 of the 20 animals tested were apneic. Three subjects recovered without intervention within 30 s and the remaining two recovered within 8 min following respiratory assistance and administration of the respiratory stimulant doxapram. Gross examination of the brain revealed no indication of bleeding. Intracranial pressures ranged from 80 to 390 kPa as a result of the blast and were notably lower than the shock tube reflected pressures of 300-2830 kPa, indicating pressure attenuation by the skull up to a factor of 8.4. Peak head accelerations were measured from 385 to 3845 G's and were well correlated with peak incident overpressure (R(2) = 0.90). One SD corridors for the surface pressure, intracranial pressure (ICP), and head acceleration are

Porcine Head Response to Blast

PubMed Central

Shridharani, Jay K.; Wood, Garrett W.; Panzer, Matthew B.; Capehart, Bruce P.; Nyein, Michelle K.; Radovitzky, Raul A.; Bass, Cameron R. ‘Dale’

2012-01-01

Recent studies have shown an increase in the frequency of traumatic brain injuries related to blast exposure. However, the mechanisms that cause blast neurotrauma are unknown. Blast neurotrauma research using computational models has been one method to elucidate that response of the brain in blast, and to identify possible mechanical correlates of injury. However, model validation against experimental data is required to ensure that the model output is representative of in vivo biomechanical response. This study exposes porcine subjects to primary blast overpressures generated using a compressed-gas shock tube. Shock tube blasts were directed to the unprotected head of each animal while the lungs and thorax were protected using ballistic protective vests similar to those employed in theater. The test conditions ranged from 110 to 740 kPa peak incident overpressure with scaled durations from 1.3 to 6.9 ms and correspond approximately with a 50% injury risk for brain bleeding and apnea in a ferret model scaled to porcine exposure. Instrumentation was placed on the porcine head to measure bulk acceleration, pressure at the surface of the head, and pressure inside the cranial cavity. Immediately after the blast, 5 of the 20 animals tested were apneic. Three subjects recovered without intervention within 30 s and the remaining two recovered within 8 min following respiratory assistance and administration of the respiratory stimulant doxapram. Gross examination of the brain revealed no indication of bleeding. Intracranial pressures ranged from 80 to 390 kPa as a result of the blast and were notably lower than the shock tube reflected pressures of 300–2830 kPa, indicating pressure attenuation by the skull up to a factor of 8.4. Peak head accelerations were measured from 385 to 3845 G’s and were well correlated with peak incident overpressure (R2 = 0.90). One SD corridors for the surface pressure, intracranial pressure (ICP), and head acceleration are

Linking blast physics to biological outcomes in mild traumatic brain injury: Narrative review and preliminary report of an open-field blast model.

PubMed

Song, Hailong; Cui, Jiankun; Simonyi, Agnes; Johnson, Catherine E; Hubler, Graham K; DePalma, Ralph G; Gu, Zezong

2018-03-15

Blast exposures are associated with traumatic brain injury (TBI) and blast-induced TBIs are common injuries affecting military personnel. Department of Defense and Veterans Administration (DoD/VA) reports for TBI indicated that the vast majority (82.3%) has been mild TBI (mTBI)/concussion. mTBI and associated posttraumatic stress disorders (PTSD) have been called "the invisible injury" of the current conflicts in Iraq and Afghanistan. These injuries induce varying degrees of neuropathological alterations and, in some cases, chronic cognitive, behavioral and neurological disorders. Appropriate animal models of blast-induced TBI will not only assist the understanding of physical characteristics of the blast, but also help to address the potential mechanisms. This report provides a brief overview of physical principles of blast, injury mechanisms related to blast exposure, current blast animal models, and the neurological behavioral and neuropathological findings related to blast injury in experimental settings. We describe relationships between blast peak pressures and the observed injuries. We also report preliminary use of a highly reproducible and intensity-graded blast murine model carried out in open-field with explosives, and describe physical and pathological findings in this experimental model. Our results indicate close relationships between blast intensities and neuropathology and behavioral deficits, particularly at low level blast intensities relevant to mTBI. Copyright © 2016 Elsevier B.V. All rights reserved.

Effects of geometry on blast-induced loadings

NASA Astrophysics Data System (ADS)

Moore, Christopher Dyer

Simulations of blasts in an urban environment were performed using Loci/BLAST, a full-featured fluid dynamics simulation code, and analyzed. A two-structure urban environment blast case was used to perform a mesh refinement study. Results show that mesh spacing on and around the structure must be 12.5 cm or less to resolve fluid dynamic features sufficiently to yield accurate results. The effects of confinement were illustrated by analyzing a blast initiated from the same location with and without the presence of a neighboring structure. Analysis of extreme pressures and impulses on structures showed that confinement can increase blast loading by more than 200 percent.

Automated real-time detection of defects during machining of ceramics

DOEpatents

Ellingson, W.A.; Sun, J.

1997-11-18

Apparatus for the automated real-time detection and classification of defects during the machining of ceramic components employs an elastic optical scattering technique using polarized laser light. A ceramic specimen is continuously moved while being machined. Polarized laser light is directed onto the ceramic specimen surface at a fixed position just aft of the machining tool for examination of the newly machined surface. Any foreign material near the location of the laser light on the ceramic specimen is cleared by an air blast. As the specimen is moved, its surface is continuously scanned by the polarized laser light beam to provide a two-dimensional image presented in real-time on a video display unit, with the motion of the ceramic specimen synchronized with the data acquisition speed. By storing known ``feature masks`` representing various surface and sub-surface defects and comparing measured defects with the stored feature masks, detected defects may be automatically characterized. Using multiple detectors, various types of defects may be detected and classified. 14 figs.

Numerical modeling and characterization of blast waves for application in blast-induced mild traumatic brain injury research

NASA Astrophysics Data System (ADS)

Phillips, Michael G.

Human exposure to blast waves, including blast-induced traumatic brain injury, is a developing field in medical research. Experiments with explosives have many disadvantages including safety, cost, and required area for trials. Shock tubes provide an alternative method to produce free field blast wave profiles. A compressed nitrogen shock tube experiment instrumented with static and reflective pressure taps is modeled using a numerical simulation. The geometry of the numerical model is simplified and blast wave characteristics are derived based upon static and pressure profiles. The pressure profiles are analyzed along the shock tube centerline and radially away from the tube axis. The blast wave parameters found from the pressure profiles provide guidelines for spatial location of a specimen. The location could be based on multiple parameters and provides a distribution of anticipated pressure profiles experience by the specimen.

30 CFR 77.1910 - Explosives and blasting; general.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Explosives and blasting; general. 77.1910... COAL MINES Slope and Shaft Sinking § 77.1910 Explosives and blasting; general. (a) Light and power circuits shall be disconnected or removed from the blasting area before charging and blasting. (b) All...

Functional Interactions of Major Rice Blast Resistance Genes Pi-ta with Pi-b and Minor Blast Resistance QTLs

USDA-ARS?s Scientific Manuscript database

Major blast resistance (R) genes confer resistance in a gene-for-gene manner. However, little information is available on interactions between R genes. In this study, interactions between two rice blast R genes, Pi-ta and Pi-b, and other minor blast resistance quantitative trait locus (QTLs) were in...

Implementation of EPICS based vacuum control system for variable energy cyclotron centre, Kolkata

NASA Astrophysics Data System (ADS)

Roy, Anindya; Bhole, R. B.; Nandy, Partha P.; Yadav, R. C.; Pal, Sarbajit; Roy, Amitava

2015-03-01

The vacuum system of the Room Temperature (K = 130) Cyclotron of Variable Energy Cyclotron Centre is comprised of vacuum systems of main machine and Beam Transport System. The vacuum control system is upgraded to a PLC based Automated system from the initial relay based Manual system. The supervisory control of the vacuum system is implemented in Experimental Physics and Industrial Control System (EPICS). An EPICS embedded ARM based vacuum gauge controller is developed to mitigate the requirement of vendor specific gauge controller for gauges and also for seamless integration of the gauge controllers with the control system. A set of MS-Windows ActiveX components with embedded EPICS Channel Access interface are developed to build operator interfaces with less complex programming and to incorporate typical Windows feature, e.g., user authentication, file handling, better fonts, colors, mouse actions etc. into the operator interfaces. The control parameters, monitoring parameters, and system interlocks of the system are archived in MySQL based EPICS MySQL Archiver developed indigenously. In this paper, we describe the architecture, the implementation details, and the performance of the system.

Implementation of EPICS based vacuum control system for variable energy cyclotron centre, Kolkata.

PubMed

Roy, Anindya; Bhole, R B; Nandy, Partha P; Yadav, R C; Pal, Sarbajit; Roy, Amitava

2015-03-01

The vacuum system of the Room Temperature (K = 130) Cyclotron of Variable Energy Cyclotron Centre is comprised of vacuum systems of main machine and Beam Transport System. The vacuum control system is upgraded to a PLC based Automated system from the initial relay based Manual system. The supervisory control of the vacuum system is implemented in Experimental Physics and Industrial Control System (EPICS). An EPICS embedded ARM based vacuum gauge controller is developed to mitigate the requirement of vendor specific gauge controller for gauges and also for seamless integration of the gauge controllers with the control system. A set of MS-Windows ActiveX components with embedded EPICS Channel Access interface are developed to build operator interfaces with less complex programming and to incorporate typical Windows feature, e.g., user authentication, file handling, better fonts, colors, mouse actions etc. into the operator interfaces. The control parameters, monitoring parameters, and system interlocks of the system are archived in MySQL based EPICS MySQL Archiver developed indigenously. In this paper, we describe the architecture, the implementation details, and the performance of the system.

Robotic Water Blast Cleaner

NASA Technical Reports Server (NTRS)

Sharpe, M. H.; Roberts, M. L.; Hill, W. E.; Jackson, C. H.

1983-01-01

Water blasting system under development removes hard, dense, extraneous material from surfaces. High pressure pump forces water at supersonic speed through nozzle manipulated by robot. Impact of water blasts away unwanted material from workpiece rotated on air bearing turntable. Designed for removing thermal-protection material, system is adaptable to such industrial processes as cleaning iron or steel castings.

Portable convertible blast effects shield

DOEpatents

Pastrnak, John W.; Hollaway, Rocky; Henning, Carl D.; Deteresa, Steve; Grundler, Walter; Hagler,; Lisle B.; Kokko, Edwin; Switzer, Vernon A

2010-10-26

A rapidly deployable portable convertible blast effects shield/ballistic shield includes a set two or more telescoping cylindrical rings operably connected to each other to convert between a telescopically-collapsed configuration for storage and transport, and a telescopically-extended upright configuration forming an expanded inner volume. In a first embodiment, the upright configuration provides blast effects shielding, such as against blast pressures, shrapnel, and/or fire balls. And in a second embodiment, the upright configuration provides ballistic shielding, such as against incoming weapons fire, shrapnel, etc. Each ring has a high-strength material construction, such as a composite fiber and matrix material, capable of substantially inhibiting blast effects and impinging projectiles from passing through the shield. And the set of rings are releasably securable to each other in the telescopically-extended upright configuration, such as by click locks.

Portable convertible blast effects shield

DOEpatents

Pastrnak, John W [Livermore, CA; Hollaway, Rocky [Modesto, CA; Henning, Carl D [Livermore, CA; Deteresa, Steve [Livermore, CA; Grundler, Walter [Hayward, CA; Hagler, Lisle B [Berkeley, CA; Kokko, Edwin [Dublin, CA; Switzer, Vernon A [Livermore, CA

2007-05-22

A rapidly deployable portable convertible blast effects shield/ballistic shield includes a set two or more telescoping cylindrical rings operably connected to each other to convert between a telescopically-collapsed configuration for storage and transport, and a telescopically-extended upright configuration forming an expanded inner volume. In a first embodiment, the upright configuration provides blast effects shielding, such as against blast pressures, shrapnel, and/or fire balls. And in a second embodiment, the upright configuration provides ballistic shielding, such as against incoming weapons fire, shrapnel, etc. Each ring has a high-strength material construction, such as a composite fiber and matrix material, capable of substantially inhibiting blast effects and impinging projectiles from passing through the shield. And the set of rings are releasably securable to each other in the telescopically-extended upright configuration, such as by click locks.

Vacuum system for room temperature X-ray lithography source (XLS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schuchman, J.C.

1988-09-30

A prototype room-temperature X-Ray Lithography Source (XLS)was proposed to be built at Brookhaven National Laboratory as part of a technology-transfer- to-American-industry program. The overall machine comprises a full energy linac, a 170 meter long transport line, and a 39 meter circumference storage ring. The scope of this paper will be limited to describing the storage ring vacuum system. (AIP)

Vacuum system for room temperature X-ray lithography source (XLS)

NASA Astrophysics Data System (ADS)

Schuchman, J. C.

1988-09-01

A prototype room-temperature X-Ray Lithography Source (XLS)was proposed to be built at Brookhaven National Laboratory as part of a technology-transfer- to-American-industry program. The overall machine comprises a full energy linac, a 170 meter long transport line, and a 39 meter circumference storage ring. The scope of this paper will be limited to describing the storage ring vacuum system. (AIP)

On the Propagation and Interaction of Spherical Blast Waves

NASA Technical Reports Server (NTRS)

Kandula, Max; Freeman, Robert

2007-01-01

The characteristics and the scaling laws of isolated spherical blast waves have been briefly reviewed. Both self-similar solutions and numerical solutions of isolated blast waves are discussed. Blast profiles in the near-field (strong shock region) and the far-field (weak shock region) are examined. Particular attention is directed at the blast overpressure and shock propagating speed. Consideration is also given to the interaction of spherical blast waves. Test data for the propagation and interaction of spherical blast waves emanating from explosives placed in the vicinity of a solid propellant stack are presented. These data are discussed with regard to the scaling laws concerning the decay of blast overpressure.

Blast investigation by fast multispectral radiometric analysis

NASA Astrophysics Data System (ADS)

Devir, A. D.; Bushlin, Y.; Mendelewicz, I.; Lessin, A. B.; Engel, M.

2011-06-01

Knowledge regarding the processes involved in blasts and detonations is required in various applications, e.g. missile interception, blasts of high-explosive materials, final ballistics and IED identification. Blasts release large amount of energy in short time duration. Some part of this energy is released as intense radiation in the optical spectral bands. This paper proposes to measure the blast radiation by a fast multispectral radiometer. The measurement is made, simultaneously, in appropriately chosen spectral bands. These spectral bands provide extensive information on the physical and chemical processes that govern the blast through the time-dependence of the molecular and aerosol contributions to the detonation products. Multi-spectral blast measurements are performed in the visible, SWIR and MWIR spectral bands. Analysis of the cross-correlation between the measured multi-spectral signals gives the time dependence of the temperature, aerosol and gas composition of the blast. Farther analysis of the development of these quantities in time may indicate on the order of the detonation and amount and type of explosive materials. Examples of analysis of measured explosions are presented to demonstrate the power of the suggested fast multispectral radiometric analysis approach.

Modeling the Blast Load Simulator Airblast Environment using First Principles Codes. Report 1, Blast Load Simulator Environment

DTIC Science & Technology

2016-11-01

ER D C/ G SL T R- 16 -3 1 Modeling the Blast Load Simulator Airblast Environment Using First Principles Codes Report 1, Blast Load...Simulator Airblast Environment using First Principles Codes Report 1, Blast Load Simulator Environment Gregory C. Bessette, James L. O’Daniel...evaluate several first principles codes (FPCs) for modeling airblast environments typical of those encountered in the BLS. The FPCs considered were

[Indirect blast rupture of the pancreas with a primary unperforated blast injury of the duodenum].

PubMed

Ignjatović, Dragan; Ignjatović, Mile; Jevtić, Miodrag

2006-02-01

To present a patient with an indirect blast rupture of the head of pancreas, as well as with a blast contusion of the duodenum following abdominal gunshot injury. A patient with the abdominal gunshot injury was submitted to the management of the injury of the liver, gaster and the right kidney in the field hospital. The revealed rupture of the head of the pancreas and the contusion of the duodenum were managed applying the method of Whipple. Indirect blast injuries require extensive surgical interventions, especially under war conditions.

Portable convertible blast effects shield

DOEpatents

Pastrnak, John W [Livermore, CA; Hollaway, Rocky [Modesto, CA; Henning, Carl D [Livermore, CA; Deteresa, Steve [Livermore, CA; Grundler, Walter [Hayward, CA; Hagler, Lisle B [Berkeley, CA; Kokko, Edwin [Dublin, CA; Switzer, Vernon A [Livermore, CA

2011-03-15

A rapidly deployable portable convertible blast effects shield/ballistic shield includes a set two or more frusto-conically-tapered telescoping rings operably connected to each other to convert between a telescopically-collapsed configuration for storage and transport, and a telescopically-extended upright configuration forming an expanded inner volume. In a first embodiment, the upright configuration provides blast effects shielding, such as against blast pressures, shrapnel, and/or fire balls. And in a second embodiment, the upright configuration provides ballistic shielding, such as against incoming weapons fire, shrapnel, etc. Each ring has a high-strength material construction, such as a composite fiber and matrix material, capable of substantially inhibiting blast effects and impinging projectiles from passing through the shield. And the set of rings are releasably securable to each other in the telescopically-extended upright configuration by the friction fit of adjacent pairs of frusto-conically-tapered rings to each other.

30 CFR 56.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Extraneous Electricity § 56.6605 Isolation of blasting circuits. Lead wires and blasting lines shall be... sources of stray or static electricity. Blasting circuits shall be protected from any contact between...

30 CFR 56.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Extraneous Electricity § 56.6605 Isolation of blasting circuits. Lead wires and blasting lines shall be... sources of stray or static electricity. Blasting circuits shall be protected from any contact between...

30 CFR 56.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Extraneous Electricity § 56.6605 Isolation of blasting circuits. Lead wires and blasting lines shall be... sources of stray or static electricity. Blasting circuits shall be protected from any contact between...

30 CFR 56.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Extraneous Electricity § 56.6605 Isolation of blasting circuits. Lead wires and blasting lines shall be... sources of stray or static electricity. Blasting circuits shall be protected from any contact between...

30 CFR 56.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Extraneous Electricity § 56.6605 Isolation of blasting circuits. Lead wires and blasting lines shall be... sources of stray or static electricity. Blasting circuits shall be protected from any contact between...

Attenuation of blast pressure behind ballistic protective vests.

PubMed

Wood, Garrett W; Panzer, Matthew B; Shridharani, Jay K; Matthews, Kyle A; Capehart, Bruce P; Myers, Barry S; Bass, Cameron R

2013-02-01

Clinical studies increasingly report brain injury and not pulmonary injury following blast exposures, despite the increased frequency of exposure to explosive devices. The goal of this study was to determine the effect of personal body armour use on the potential for primary blast injury and to determine the risk of brain and pulmonary injury following a blast and its impact on the clinical care of patients with a history of blast exposure. A shock tube was used to generate blast overpressures on soft ballistic protective vests (NIJ Level-2) and hard protective vests (NIJ Level-4) while overpressure was recorded behind the vest. Both types of vest were found to significantly decrease pulmonary injury risk following a blast for a wide range of conditions. At the highest tested blast overpressure, the soft vest decreased the behind armour overpressure by a factor of 14.2, and the hard vest decreased behind armour overpressure by a factor of 56.8. Addition of body armour increased the 50th percentile pulmonary death tolerance of both vests to higher levels than the 50th percentile for brain injury. These results suggest that ballistic protective body armour vests, especially hard body armour plates, provide substantial chest protection in primary blasts and explain the increased frequency of head injuries, without the presence of pulmonary injuries, in protected subjects reporting a history of blast exposure. These results suggest increased clinical suspicion for mild to severe brain injury is warranted in persons wearing body armour exposed to a blast with or without pulmonary injury.

[An experimental study of blast injury].

PubMed

Wang, Z G

1989-01-01

This paper presents some aspects of the authors' experimental research on blast injury in the past two years. The main results are as follows: (1) A new designed 39 meter-long shock tube for biological test has been built in the laboratory. Its maximal overpressure values are 215 kPa (in open condition) and 505 kPa (in closed condition). It may meet the need for inflicting blast injuries with various degree of severity. (2) A study of the effect of simulating gun muzzle blast wave on sheep indicated that in the single explosion, the threshold overpressure values inflicting the injury of internal organs were: Lung-37.27 kPa, G-I tract-41.0 kPa; the upper respiratory tract-negative until 73 kPa, while in the multiple (20 times) explosions, they were 23.7, 23.7 and 41.4 kPa, respectively. (3) Using TEM, SEM and some other special techniques, such as morphometry, freeze-fracture technique, labelled lanthanum nitrate technique, etc, it was demonstrated that in the lung with blast injury there were significant pathological changes in pulmonary capillary endothelium, alveolar epithelium and their intercellular junctions with apparent increase of permeability. (4) It has been shown that parallel superficial stripelike hemorrhage typical for lung blast injury is "Intercostal marking" instead of "Rib marking". (5) A new type of material (foamy nickel) for protection against blast wave is presented. It was proved that the material can effectively weaken or eliminate the effect of blast wave on human body.

Blast-induced phenotypic switching in cerebral vasospasm

PubMed Central

Alford, Patrick W.; Dabiri, Borna E.; Goss, Josue A.; Hemphill, Matthew A.; Brigham, Mark D.; Parker, Kevin Kit

2011-01-01

Vasospasm of the cerebrovasculature is a common manifestation of blast-induced traumatic brain injury (bTBI) reported among combat casualties in the conflicts in Afghanistan and Iraq. Cerebral vasospasm occurs more frequently, and with earlier onset, in bTBI patients than in patients with other TBI injury modes, such as blunt force trauma. Though vasospasm is usually associated with the presence of subarachnoid hemorrhage (SAH), SAH is not required for vasospasm in bTBI, which suggests that the unique mechanics of blast injury could potentiate vasospasm onset, accounting for the increased incidence. Here, using theoretical and in vitro models, we show that a single rapid mechanical insult can induce vascular hypercontractility and remodeling, indicative of vasospasm initiation. We employed high-velocity stretching of engineered arterial lamellae to simulate the mechanical forces of a blast pulse on the vasculature. An hour after a simulated blast, injured tissues displayed altered intracellular calcium dynamics leading to hypersensitivity to contractile stimulus with endothelin-1. One day after simulated blast, tissues exhibited blast force dependent prolonged hypercontraction and vascular smooth muscle phenotype switching, indicative of remodeling. These results suggest that an acute, blast-like injury is sufficient to induce a hypercontraction-induced genetic switch that potentiates vascular remodeling, and cerebral vasospasm, in bTBI patients. PMID:21765001

Low Level Primary Blast Injury in Rodent Brain

PubMed Central

Pun, Pamela B. L.; Kan, Enci Mary; Salim, Agus; Li, Zhaohui; Ng, Kian Chye; Moochhala, Shabbir M.; Ling, Eng-Ang; Tan, Mui Hong; Lu, Jia

2011-01-01

The incidence of blast attacks and resulting traumatic brain injuries has been on the rise in recent years. Primary blast is one of the mechanisms in which the blast wave can cause injury to the brain. The aim of this study was to investigate the effects of a single sub-lethal blast over pressure (BOP) exposure of either 48.9 kPa (7.1 psi) or 77.3 kPa (11.3 psi) to rodents in an open-field setting. Brain tissue from these rats was harvested for microarray and histopathological analyses. Gross histopathology of the brains showed that cortical neurons were “darkened” and shrunken with narrowed vasculature in the cerebral cortex day 1 after blast with signs of recovery at day 4 and day 7 after blast. TUNEL-positive cells were predominant in the white matter of the brain at day 1 after blast and double-labeling of brain tissue showed that these DNA-damaged cells were both oligodendrocytes and astrocytes but were mainly not apoptotic due to the low caspase-3 immunopositivity. There was also an increase in amyloid precursor protein immunoreactive cells in the white matter which suggests acute axonal damage. In contrast, Iba-1 staining for macrophages or microglia was not different from control post-blast. Blast exposure altered the expression of over 5786 genes in the brain which occurred mostly at day 1 and day 4 post-blast. These genes were narrowed down to 10 overlapping genes after time-course evaluation and functional analyses. These genes pointed toward signs of repair at day 4 and day 7 post-blast. Our findings suggest that the BOP levels in the study resulted in mild cellular injury to the brain as evidenced by acute neuronal, cerebrovascular, and white matter perturbations that showed signs of resolution. It is unclear whether these perturbations exist at a milder level or normalize completely and will need more investigation. Specific changes in gene expression may be further evaluated to understand the mechanism of blast-induced neurotrauma. PMID

Blasting CME

NASA Image and Video Library

2017-12-08

This LASCO C2 image, taken 8 January 2002, shows a widely spreading coronal mass ejection (CME) as it blasts more than a billion tons of matter out into space at millions of kilometers per hour. The C2 image was turned 90 degrees so that the blast seems to be pointing down. An EIT 304 Angstrom image from a different day was enlarged and superimposed on the C2 image so that it filled the occulting disk for effect. Credit: NASA/GSFC/SOHO/ESA To learn more go to the SOHO website: sohowww.nascom.nasa.gov/home.html To learn more about NASA's Sun Earth Day go here: sunearthday.nasa.gov/2010/index.php

Investigation of blast-induced traumatic brain injury.

PubMed

Taylor, Paul A; Ludwigsen, John S; Ford, Corey C

2014-01-01

Many troops deployed in Iraq and Afghanistan have sustained blast-related, closed-head injuries from being within non-lethal distance of detonated explosive devices. Little is known, however, about the mechanisms associated with blast exposure that give rise to traumatic brain injury (TBI). This study attempts to identify the precise conditions of focused stress wave energy within the brain, resulting from blast exposure, which will correlate with a threshold for persistent brain injury. This study developed and validated a set of modelling tools to simulate blast loading to the human head. Using these tools, the blast-induced, early-time intracranial wave motions that lead to focal brain damage were simulated. The simulations predict the deposition of three distinct wave energy components, two of which can be related to injury-inducing mechanisms, namely cavitation and shear. Furthermore, the results suggest that the spatial distributions of these damaging energy components are independent of blast direction. The predictions reported herein will simplify efforts to correlate simulation predictions with clinical measures of TBI and aid in the development of protective headwear.

Investigation of blast-induced traumatic brain injury

PubMed Central

Ludwigsen, John S.; Ford, Corey C.

2014-01-01

Objective Many troops deployed in Iraq and Afghanistan have sustained blast-related, closed-head injuries from being within non-lethal distance of detonated explosive devices. Little is known, however, about the mechanisms associated with blast exposure that give rise to traumatic brain injury (TBI). This study attempts to identify the precise conditions of focused stress wave energy within the brain, resulting from blast exposure, which will correlate with a threshold for persistent brain injury. Methods This study developed and validated a set of modelling tools to simulate blast loading to the human head. Using these tools, the blast-induced, early-time intracranial wave motions that lead to focal brain damage were simulated. Results The simulations predict the deposition of three distinct wave energy components, two of which can be related to injury-inducing mechanisms, namely cavitation and shear. Furthermore, the results suggest that the spatial distributions of these damaging energy components are independent of blast direction. Conclusions The predictions reported herein will simplify efforts to correlate simulation predictions with clinical measures of TBI and aid in the development of protective headwear. PMID:24766453

An investigation of the effect of rapid slurry chilling on blown pack spoilage of vacuum-packaged beef primals.

PubMed

Reid, R; Fanning, S; Whyte, P; Kerry, J; Bolton, D

2017-02-01

The aim of this study was to investigate if rapid slurry chilling would retard or prevent blown pack spoilage (BPS) of vacuum-packaged beef primals. Beef primals were inoculated with Clostridium estertheticum subspp. estertheticum (DSMZ 8809), C. estertheticum subspp. laramenise (DSMZ 14864) and C. gasigenes (DSMZ 12272), and vacuum-packaged with and without heat shrinkage (90°C for 3 s). These packs were then subjected to immediate chilling in an ice slurry or using conventional blast chilling systems and stored at 2°C for up to 100 days. The onset and progress of BPS was monitored using the following scale; 0-no gas bubbles in drip; 1-gas bubbles in drip; 2-loss of vacuum; 3-'blown'; 4-presence of sufficient gas inside the packs to produce pack distension and 5-tightly stretched, 'overblown' packs/packs leaking. Rapid slurry chilling (as compared to conventional chilling) did not significantly affect (P > 0.05) the time to the onset or progress of BPS. It was therefore concluded that rapid chilling of vacuum-packaged beef primals, using an ice slurry system, may not be used as a control intervention to prevent or retard blown pack spoilage. This study adds to our growing understanding of blown pack spoilage of vacuum-packaged beef primals and suggests that rapid chilling of vacuum-packaged beef primals is not a control option for the beef industry. The results suggest that neither eliminating the heat shrinkage step nor rapid chilling of vacuum-packaged beef retard the time to blown pack spoilage. © 2016 The Society for Applied Microbiology.

Efficacy of dry-ice blasting in preventive maintenance of auto robotic assemblies

NASA Astrophysics Data System (ADS)

Baluch, Nazim; Mohtar, Shahimi; Abdullah, Che Sobry

2016-08-01

Welding robots are extensively applied in the automotive assemblies and `Spot Welding' is the most common welding application found in the auto stamping assembly manufacturing. Every manufacturing process is subject to variations - with resistance welding, these include; part fit up, part thickness variations, misaligned electrodes, variations in coating materials or thickness, sealers, weld force variations, shunting, machine tooling degradation; and slag and spatter damage. All welding gun tips undergo wear; an elemental part of the process. Though adaptive resistance welding control automatically compensates to keep production and quality up to the levels needed as gun tips undergo wear so that the welds remain reliable; the system cannot compensate for deterioration caused by the slag and spatter on the part holding fixtures, sensors, and gun tips. To cleanse welding robots of slag and spatter, dry-ice blasting has proven to be an effective remedy. This paper describes Spot welding process, analyses the slag and spatter formation during robotic welding of stamping assemblies, and concludes that the dry ice blasting process's utility in cleansing of welding robots in auto stamping plant operations is paramount and exigent.

Predictive control of thermal state of blast furnace

NASA Astrophysics Data System (ADS)

Barbasova, T. A.; Filimonova, A. A.

2018-05-01

The work describes the structure of the model for predictive control of the thermal state of a blast furnace. The proposed model contains the following input parameters: coke rate; theoretical combustion temperature, comprising: natural gas consumption, blasting temperature, humidity, oxygen, blast furnace cooling water; blast furnace gas utilization rate. The output parameter is the cast iron temperature. The results for determining the cast iron temperature were obtained following the identification using the Hammerstein-Wiener model. The result of solving the cast iron temperature stabilization problem was provided for the calculated values of process parameters of the target area of the respective blast furnace operation mode.

Implementation of EPICS based vacuum control system for variable energy cyclotron centre, Kolkata

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy, Anindya, E-mail: r-ani@vecc.gov.in; Bhole, R. B.; Nandy, Partha P.

2015-03-15

The vacuum system of the Room Temperature (K = 130) Cyclotron of Variable Energy Cyclotron Centre is comprised of vacuum systems of main machine and Beam Transport System. The vacuum control system is upgraded to a PLC based Automated system from the initial relay based Manual system. The supervisory control of the vacuum system is implemented in Experimental Physics and Industrial Control System (EPICS). An EPICS embedded ARM based vacuum gauge controller is developed to mitigate the requirement of vendor specific gauge controller for gauges and also for seamless integration of the gauge controllers with the control system. A setmore » of MS-Windows ActiveX components with embedded EPICS Channel Access interface are developed to build operator interfaces with less complex programming and to incorporate typical Windows feature, e.g., user authentication, file handling, better fonts, colors, mouse actions etc. into the operator interfaces. The control parameters, monitoring parameters, and system interlocks of the system are archived in MySQL based EPICS MySQL Archiver developed indigenously. In this paper, we describe the architecture, the implementation details, and the performance of the system.« less

Military blast exposure, ageing and white matter integrity

PubMed Central

Trotter, Benjamin B.; Robinson, Meghan E.; Milberg, William P.; McGlinchey, Regina E.

2015-01-01

Mild traumatic brain injury, or concussion, is associated with a range of neural changes including altered white matter structure. There is emerging evidence that blast exposure—one of the most pervasive causes of casualties in the recent overseas conflicts in Iraq and Afghanistan—is accompanied by a range of neurobiological events that may result in pathological changes to brain structure and function that occur independently of overt concussion symptoms. The potential effects of brain injury due to blast exposure are of great concern as a history of mild traumatic brain injury has been identified as a risk factor for age-associated neurodegenerative disease. The present study used diffusion tensor imaging to investigate whether military-associated blast exposure influences the association between age and white matter tissue structure integrity in a large sample of veterans of the recent conflicts (n = 190 blast-exposed; 59 without exposure) between the ages of 19 and 62 years. Tract-based spatial statistics revealed a significant blast exposure × age interaction on diffusion parameters with blast-exposed individuals exhibiting a more rapid cross-sectional age trajectory towards reduced tissue integrity. Both distinct and overlapping voxel clusters demonstrating the interaction were observed among the examined diffusion contrast measures (e.g. fractional anisotropy and radial diffusivity). The regions showing the effect on fractional anisotropy included voxels both within and beyond the boundaries of the regions exhibiting a significant negative association between fractional anisotropy and age in the entire cohort. The regional effect was sensitive to the degree of blast exposure, suggesting a ‘dose-response’ relationship between the number of blast exposures and white matter integrity. Additionally, there was an age-independent negative association between fractional anisotropy and years since most severe blast exposure in a subset of the blast

29 CFR 1926.912 - Underwater blasting.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Underwater blasting. (a) A blaster shall conduct all blasting operations, and no shot shall be fired without... herein on handling and storing explosives. (h) When more than one charge is placed under water, a float...

29 CFR 1926.912 - Underwater blasting.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Underwater blasting. (a) A blaster shall conduct all blasting operations, and no shot shall be fired without... herein on handling and storing explosives. (h) When more than one charge is placed under water, a float...

29 CFR 1926.912 - Underwater blasting.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Underwater blasting. (a) A blaster shall conduct all blasting operations, and no shot shall be fired without... herein on handling and storing explosives. (h) When more than one charge is placed under water, a float...

29 CFR 1926.912 - Underwater blasting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Underwater blasting. (a) A blaster shall conduct all blasting operations, and no shot shall be fired without... herein on handling and storing explosives. (h) When more than one charge is placed under water, a float...

29 CFR 1926.912 - Underwater blasting.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Underwater blasting. (a) A blaster shall conduct all blasting operations, and no shot shall be fired without... herein on handling and storing explosives. (h) When more than one charge is placed under water, a float...

Vacuum Arc Vapor Deposition Method and Apparatus for Applying Identification Symbols to Substrates

NASA Technical Reports Server (NTRS)

Schramm, Harry F. (Inventor); Roxby, Donald L. (Inventor); Weeks, Jack L. (Inventor)

2002-01-01

An apparatus for applying permanent markings onto products using a Vacuum Arc Vapor Deposition (VAVD) marker by accelerating atoms or molecules from a vaporization source onto a substrate to form human and/or machine-readable part identification marking that can be detected optically or via a sensing device like x-ray, thermal imaging, ultrasound, magneto-optic, micro-power impulse radar, capacitance, or other similar sensing means. The apparatus includes a housing with a nozzle having a marking end. A chamber having an electrode, a vacuum port and a charge is located within the housing. The charge is activated by the electrode in a vacuum environment and deposited onto a substrate at the marking end of the nozzle. The apparatus may be a hand-held device or be disconnected from the handle and mounted to a robot or fixed station.

Efficacy of Cruise Control in controlling postocclusion surge with Legacy and Millennium venturi phacoemulsification machines.

PubMed

Wade, Matthew; Isom, Ryan; Georgescu, Dan; Olson, Randall J

2007-06-01

To determine the efficacy of the Cruise Control surge-limiting device (Staar Surgical) with phacoemulsification machines known to have high levels of surge. John A. Moran Eye Center Clinical Laboratories. In an in vitro study, postocclusion anterior chamber depth changes were measured in fresh phakic human eye-bank eyes using the Alcon Legacy and Bausch & Lomb Millennium venturi machines in conjunction with the Staar Cruise Control device. Both machines were tested with 19-gauge non-Aspiration Bypass System tips at high-surge settings (500 mm Hg vacuum pressure, 75 cm bottle height, 40 mL/min flow rate for the Legacy) and low-surge settings (400 mm Hg vacuum pressure, 125 cm bottle height, 40 mL/min flow rate for the Legacy). Adjusted parameters of flow, vacuum, and irrigation were used based on previous studies to create identical conditions for each device tested. The effect of the Cruise Control device on aspiration rates was also tested with both machines at the low-surge settings. At the high setting with the addition of Cruise Control, surge decreased significantly with the Legacy but was too large to measure with the Millennium venturi. At the low setting with the addition of Cruise Control, surge decreased significantly with both machines. Surge with the Millennium decreased from more than 1.0 mm to a mean of 0.21 mm +/- 0.02 (SD) (P<.0001). Surge with the Legacy decreased from a mean of 0.09 +/- 0.02 mm to 0.05 +/- 0 mm, a 42.9% decrease (P<.0001). The Millennium had the highest surge and aspiration rate before Cruise Control and the greatest percentage decrease in the surge and aspiration rates as a result of the addition of Cruise Control. In the Legacy machine, the Cruise Control device had a statistically and clinically significant effect. Cruise Control had a large effect on fluidics as well as surge amplitude with the Millennium machine. The greater the flow or greater the initial surge, the greater the impact of the Cruise Control device.

Micro Dot Patterning on the Light Guide Panel Using Powder Blasting.

PubMed

Jang, Ho Su; Cho, Myeong Woo; Park, Dong Sam

2008-02-08

This study is to develop a micromachining technology for a light guidepanel(LGP) mold, whereby micro dot patterns are formed on a LGP surface by a singleinjection process instead of existing screen printing processes. The micro powder blastingtechnique is applied to form micro dot patterns on the LGP mold surface. The optimalconditions for masking, laminating, exposure, and developing processes to form the microdot patterns are first experimentally investigated. A LGP mold with masked micro patternsis then machined using the micro powder blasting method and the machinability of themicro dot patterns is verified. A prototype LGP is test- injected using the developed LGPmold and a shape analysis of the patterns and performance testing of the injected LGP arecarried out. As an additional approach, matte finishing, a special surface treatment method,is applied to the mold surface to improve the light diffusion characteristics, uniformity andbrightness of the LGP. The results of this study show that the applied powder blastingmethod can be successfully used to manufacture LGPs with micro patterns by just singleinjection using the developed mold and thereby replace existing screen printing methods.

LHCb experience with running jobs in virtual machines

NASA Astrophysics Data System (ADS)

McNab, A.; Stagni, F.; Luzzi, C.

2015-12-01

The LHCb experiment has been running production jobs in virtual machines since 2013 as part of its DIRAC-based infrastructure. We describe the architecture of these virtual machines and the steps taken to replicate the WLCG worker node environment expected by user and production jobs. This relies on the uCernVM system for providing root images for virtual machines. We use the CernVM-FS distributed filesystem to supply the root partition files, the LHCb software stack, and the bootstrapping scripts necessary to configure the virtual machines for us. Using this approach, we have been able to minimise the amount of contextualisation which must be provided by the virtual machine managers. We explain the process by which the virtual machine is able to receive payload jobs submitted to DIRAC by users and production managers, and how this differs from payloads executed within conventional DIRAC pilot jobs on batch queue based sites. We describe our operational experiences in running production on VM based sites managed using Vcycle/OpenStack, Vac, and HTCondor Vacuum. Finally we show how our use of these resources is monitored using Ganglia and DIRAC.

Indian Vacuum Society: The Indian Vacuum Society

NASA Astrophysics Data System (ADS)

Saha, T. K.

2008-03-01

The Indian Vacuum Society (IVS) was established in 1970. It has over 800 members including many from Industry and R & D Institutions spread throughout India. The society has an active chapter at Kolkata. The society was formed with the main aim to promote, encourage and develop the growth of Vacuum Science, Techniques and Applications in India. In order to achieve this aim it has conducted a number of short term courses at graduate and technician levels on vacuum science and technology on topics ranging from low vacuum to ultrahigh vacuum So far it has conducted 39 such courses at different parts of the country and imparted training to more than 1200 persons in the field. Some of these courses were in-plant training courses conducted on the premises of the establishment and designed to take care of the special needs of the establishment. IVS also regularly conducts national and international seminars and symposia on vacuum science and technology with special emphasis on some theme related to applications of vacuum. A large number of delegates from all over India take part in the deliberations of such seminars and symposia and present their work. IVS also arranges technical visits to different industries and research institutes. The society also helped in the UNESCO sponsored post-graduate level courses in vacuum science, technology and applications conducted by Mumbai University. The society has also designed a certificate and diploma course for graduate level students studying vacuum science and technology and has submitted a syllabus to the academic council of the University of Mumbai for their approval, we hope that some colleges affiliated to the university will start this course from the coming academic year. IVS extended its support in standardizing many of the vacuum instruments and played a vital role in helping to set up a Regional Testing Centre along with BARC. As part of the development of vacuum education, the society arranges the participation of

Mechanical and Histological Effects of Resorbable Blasting Media Surface Treatment on the Initial Stability of Orthodontic Mini-Implants

PubMed Central

2016-01-01

Introduction. This study aimed to evaluate the effects of resorbable blasting media (RBM) treatment on early stability of orthodontic mini-implants by mechanical, histomorphometric, and histological analyses. Methods. Ninety-six (64 for mechanical study and 32 for histological study and histomorphometric analysis) titanium orthodontic mini-implants (OMIs) with machined (machined group) or RBM-treated (CaP) surface (RBM group) were implanted in the tibiae of 24 rabbits. Maximum initial torque (MIT) was measured during insertion, and maximum removal torque (MRT) and removal angular momentum (RAM) were measured at 2 and 4 weeks after implantation. Bone-to-implant contact (BIC) and bone area (BA) were analyzed at 4 weeks after implantation. Results. RBM group exhibited significantly lower MIT and significantly higher MRT and RAM at 2 weeks than machined group. No significant difference in MRT, RAM, and BIC between the two groups was noted at 4 weeks, although BA was significantly higher in RBM group than in machined group. RBM group showed little bone resorption, whereas machined group showed new bone formation after bone resorption. Conclusions. RBM surface treatment can provide early stability of OMIs around 2 weeks after insertion, whereas stability of machined surface OMIs may decrease in early stages because of bone resorption, although it can subsequently recover by new bone apposition. PMID:26942200

Vacuum testing of high efficiency AMTEC cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schuller, M.; Phillips, P.H.; Sievers, R.

1996-12-31

The Phillips Laboratory Power and Thermal Management Division (PL/VTP), in cooperation with JPL, AMPS, Creare, and ORION, is performing vacuum testing of high performance Alkali Metal Thermal to Electric Conversion (AMTEC) cells, including the Micro-Machined Evaporator (MME) and PL-9A cells. The MME cell was designed to test an improved evaporator, which should allow long term operation at evaporator temperatures as high as 1,100 K. The PL-9A cell was designed and built by AMPS under contract to ORION to test an improved heat shield assembly. The testing at Phillips Lab is done in a vacuum test stand which simulates the environmentmore » of an AMTEC cell operating as part of a spacecraft power system. The test configuration consists of the MME cell (later replaced by by the PL-9A cell) in the center of an array of six other AMTEC cells. The seven cells are encased in multifoil insulation. Testing shows that there is little difference between cell current/voltage performance when measured in vacuum tests compared to guard heater tests. The author are also examining the differences between fast I-V curve sweeps, recorded manually, with the cell operating at constant heat input, over a period of five minutes or less, and equilibrium I-V curve sweeps, in which the cell reaches thermal equilibrium at each data point.« less

Full-scale testing of leakage of blast waves inside a partially vented room exposed to external air blast loading

NASA Astrophysics Data System (ADS)

Codina, R.; Ambrosini, D.

2018-03-01

For the last few decades, the effects of blast loading on structures have been studied by many researchers around the world. Explosions can be caused by events such as industrial accidents, military conflicts or terrorist attacks. Urban centers have been prone to various threats including car bombs, suicide attacks, and improvised explosive devices. Partially vented constructions subjected to external blast loading represent an important topic in protective engineering. The assessment of blast survivability inside structures and the development of design provisions with respect to internal elements require the study of the propagation and leakage of blast waves inside buildings. In this paper, full-scale tests are performed to study the effects of the leakage of blast waves inside a partially vented room that is subjected to different external blast loadings. The results obtained may be useful for proving the validity of different methods of calculation, both empirical and numerical. Moreover, the experimental results are compared with those computed using the empirical curves of the US Defense report/manual UFC 3-340. Finally, results of the dynamic response of the front masonry wall are presented in terms of accelerations and an iso-damage diagram.

Temporal Progression of Visual Injury from Blast Exposure

DTIC Science & Technology

2013-09-01

carprofen one day before the blast for pain management. A baseline of vision functionality is established before the blast using the metrics...returned to the animal facility. While animals do not show signs of pain following the blast exposure, carprofen is administered the next day as a

Blast furnace supervision and control system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Remorino, M.; Lingiardi, O.; Zecchi, M.

1997-12-31

On December 1992, a group of companies headed by Techint, took over Somisa, the state-owned integrated steel plant located at San Nicolas, Province of Buenos Aires, Argentina, culminating an ambitious government privatization scheme. The blast furnace 2 went into a full reconstruction and relining in January 1995. After a 140 MU$ investment the new blast furnace 2 was started in September 1995. After more than one year of operation of the blast furnace the system has proven itself useful and reliable. The main reasons for the success of the system are: same use interface for all blast furnace areas --more » operation, process, maintenance and management, (full horizontal and vertical integration); and full accessibility to all information and process tools though some restrictions apply to field commands (people empowerment). The paper describes the central system.« less

BLAST FURNACE CAST HOUSE EMISSION CONTROL TECHNOLOGY ASSESSMENT

EPA Science Inventory

The study describes the state-of-the-art of controlling fumes escaping from blast furnace cast houses. Background information is based on: a study of existing literature; visits to blast furnaces in the U.S., Japan, and Europe; meetings with an ad hoc group of experienced blast f...

Otologic blast injuries due to the Kenya embassy bombing.

PubMed

Helling, Eric Robert

2004-11-01

Otologic injuries are frequently associated with large blasts. On August 7, 1998, a large truck bomb exploded next to the U.S. Embassy in Nairobi, Kenya. Initial patient findings and care are reviewed. Five months later, an otologic screening and care mission was then sent to comprehensively screen all remaining blast victims on site in Nairobi and to determine degree of persistent injury. Surgical care appropriate for an outpatient environment was provided. Five of 14 tympanic membranes without intervention failed to heal, while 3 of 3 with previous intervention had. Blast injury severity did not correlate to distance from blast epicenter. This may be due to channeling of the blast through the embassy building and an unpredictable pattern of blast overpressure within the building. It is recommended that comprehensive otologic screening be performed after blast events to identify occult injuries and improve outcomes. Early intervention for tympanic membrane perforation (suctioning, eversion of perforations, and paper patch) is recommended.

Development and fabrication of the vacuum systems for an elliptically polarized undulator at Taiwan Photon Source

NASA Astrophysics Data System (ADS)

Chang, Chin-Chun; Chan, Che-Kai; Wu, Ling-Hui; Shueh, Chin; Shen, I.-Ching; Cheng, Chia-Mu; Yang, I.-Chen

2017-05-01

Three sets of a vacuum system were developed and fabricated for elliptically polarized undulators (EPU) of a 3-GeV synchrotron facility. These chambers were shaped with low roughness extrusion and oil-free machining; the design combines aluminium and stainless steel. The use of a bimetallic material to connect the EPU to the vacuum system achieves the vacuum sealing and to resolve the leakage issue due to bake process induced thermal expansion difference. The interior of the EPU chamber consists of a non-evaporable-getter strip pump in a narrow space to absorb photon-stimulated desorption and to provide a RF bridge design to decrease impedance effect in the two ends of EPU chamber. To fabricate these chambers and to evaluate the related performance, we performed a computer simulation to optimize the structure. During the machining and welding, the least deformation was achieved, less than 0.1 mm near 4 m. In the installation, the linear slider can provide a stable and precision moved along parallel the electron beam direction smoothly for the EPU chamber to decrease the twist issue during baking process. The pressure of the EPU chamber attained less than 2×10-8 Pa through baking. These vacuum systems of the EPU magnet have been installed in the electron storage ring of Taiwan Photon Source in 2015 May and have normally operated at 300 mA continuously since, and to keep beam life time achieved over than 12 h.

On firework blasts and qualitative parameter dependency.

PubMed

Zohdi, T I

2016-01-01

In this paper, a mathematical model is developed to qualitatively simulate the progressive time-evolution of a blast from a simple firework. Estimates are made for the blast radius that one can expect for a given amount of detonation energy and pyrotechnic display material. The model balances the released energy from the initial blast pulse with the subsequent kinetic energy and then computes the trajectory of the material under the influence of the drag from the surrounding air, gravity and possible buoyancy. Under certain simplifying assumptions, the model can be solved for analytically. The solution serves as a guide to identifying key parameters that control the evolving blast envelope. Three-dimensional examples are given.

Bomb blast imaging: bringing order to chaos.

PubMed

Dick, E A; Ballard, M; Alwan-Walker, H; Kashef, E; Batrick, N; Hettiaratchy, S; Moran, C G

2018-06-01

Blast injuries are complex, severe, and outside of our everyday clinical practice, but every radiologist needs to understand them. By their nature, bomb blasts are unpredictable and affect multiple victims, yet require an immediate, coordinated, and whole-hearted response from all members of the clinical team, including all radiology staff. This article will help you gain the requisite expertise in blast imaging including recognising primary, secondary, and tertiary blast injuries. It will also help you understand the fundamental role that imaging plays during mass casualty attacks and how to avoid radiology becoming a bottleneck to the forward flow of severely injured patients as they are triaged and treated. Copyright © 2018. Published by Elsevier Ltd.

On firework blasts and qualitative parameter dependency

PubMed Central

Zohdi, T. I.

2016-01-01

In this paper, a mathematical model is developed to qualitatively simulate the progressive time-evolution of a blast from a simple firework. Estimates are made for the blast radius that one can expect for a given amount of detonation energy and pyrotechnic display material. The model balances the released energy from the initial blast pulse with the subsequent kinetic energy and then computes the trajectory of the material under the influence of the drag from the surrounding air, gravity and possible buoyancy. Under certain simplifying assumptions, the model can be solved for analytically. The solution serves as a guide to identifying key parameters that control the evolving blast envelope. Three-dimensional examples are given. PMID:26997903

Comment on "chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model".

PubMed

Tisdall, Martin; Petzold, Axel

2012-10-24

In a case study, the authors report an increase in phosphorylated neurofilament heavy chain, a marker of neuroaxonal damage, in the plasma of a blast-exposed patient immediately after injury. They suggest that this phosphoprotein may be a useful body fluid indicator of acute blast traumatic brain injury.

Distinguishing the Unique Neuropathological Profile of Blast Polytrauma

PubMed Central

Greenberg, Shaylen; Eck, Joseph; Lavik, Erin

2017-01-01

Traumatic brain injury sustained after blast exposure (blast-induced TBI) has recently been documented as a growing issue for military personnel. Incidence of injury to organs such as the lungs has decreased, though current epidemiology still causes a great public health burden. In addition, unprotected civilians sustain primary blast lung injury (PBLI) at alarming rates. Often, mild-to-moderate cases of PBLI are survivable with medical intervention, which creates a growing population of survivors of blast-induced polytrauma (BPT) with symptoms from blast-induced mild TBI (mTBI). Currently, there is a lack of preclinical models simulating BPT, which is crucial to identifying unique injury mechanisms of BPT and its management. To meet this need, our group characterized a rodent model of BPT and compared results to a blast-induced mTBI model. Open field (OF) performance trials were performed on rodents at 7 days after injury. Immunohistochemistry was performed to evaluate cellular outcome at day seven following BPT. Levels of reactive astrocytes (GFAP), apoptosis (cleaved caspase-3 expression), and vascular damage (SMI-71) were significantly elevated in BPT compared to blast-induced mTBI. Downstream markers of hypoxia (HIF-1α and VEGF) were higher only after BPT. This study highlights the need for unique therapeutics and prehospital management when handling BPT. PMID:28424745

30 CFR 57.6312 - Secondary blasting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Explosives Transportation-Surface and Underground § 57.6312 Secondary blasting. Secondary blasts fired at the same time in...

Compressive strength after blast of sandwich composite materials

PubMed Central

Arora, H.; Kelly, M.; Worley, A.; Del Linz, P.; Fergusson, A.; Hooper, P. A.; Dear, J. P.

2014-01-01

Composite sandwich materials have yet to be widely adopted in the construction of naval vessels despite their excellent strength-to-weight ratio and low radar return. One barrier to their wider use is our limited understanding of their performance when subjected to air blast. This paper focuses on this problem and specifically the strength remaining after damage caused during an explosion. Carbon-fibre-reinforced polymer (CFRP) composite skins on a styrene–acrylonitrile (SAN) polymer closed-cell foam core are the primary composite system evaluated. Glass-fibre-reinforced polymer (GFRP) composite skins were also included for comparison in a comparable sandwich configuration. Full-scale blast experiments were conducted, where 1.6×1.3 m sized panels were subjected to blast of a Hopkinson–Cranz scaled distance of 3.02 m kg−1/3, 100 kg TNT equivalent at a stand-off distance of 14 m. This explosive blast represents a surface blast threat, where the shockwave propagates in air towards the naval vessel. Hopkinson was the first to investigate the characteristics of this explosive air-blast pulse (Hopkinson 1948 Proc. R. Soc. Lond. A 89, 411–413 (doi:10.1098/rspa.1914.0008)). Further analysis is provided on the performance of the CFRP sandwich panel relative to the GFRP sandwich panel when subjected to blast loading through use of high-speed speckle strain mapping. After the blast events, the residual compressive load-bearing capacity is investigated experimentally, using appropriate loading conditions that an in-service vessel may have to sustain. Residual strength testing is well established for post-impact ballistic assessment, but there has been less research performed on the residual strength of sandwich composites after blast. PMID:24711494

22 CFR 121.11 - Military demolition blocks and blasting caps.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Military demolition blocks and blasting caps... blasting caps. Military demolition blocks and blasting caps referred to in Category IV(a) do not include the following articles: (a) Electric squibs. (b) No. 6 and No. 8 blasting caps, including electric...

29 CFR 1926.905 - Loading of explosives or blasting agents.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 8 2010-07-01 2010-07-01 false Loading of explosives or blasting agents. 1926.905 Section... Explosives § 1926.905 Loading of explosives or blasting agents. (a) Procedures that permit safe and efficient... have contained explosives or blasting agents. (g) No explosives or blasting agents shall be left...

Investigations of primary blast-induced traumatic brain injury

NASA Astrophysics Data System (ADS)

Sawyer, T. W.; Josey, T.; Wang, Y.; Villanueva, M.; Ritzel, D. V.; Nelson, P.; Lee, J. J.

2018-01-01

The development of an advanced blast simulator (ABS) has enabled the reproducible generation of single-pulse shock waves that simulate free-field blast with high fidelity. Studies with rodents in the ABS demonstrated the necessity of head restraint during head-only exposures. When the head was not restrained, violent global head motion was induced by pressures that would not produce similar movement of a target the size and mass of a human head. This scaling artefact produced changes in brain function that were reminiscent of traumatic brain injury (TBI) due to impact-acceleration effects. Restraint of the rodent head eliminated these, but still produced subtle changes in brain biochemistry, showing that blast-induced pressure waves do cause brain deficits. Further experiments were carried out with rat brain cell aggregate cultures that enabled the conduct of studies without the gross movement encountered when using rodents. The suspension nature of this model was also exploited to minimize the boundary effects that complicate the interpretation of primary blast studies using surface cultures. Using this system, brain tissue was found not only to be sensitive to pressure changes, but also able to discriminate between the highly defined single-pulse shock waves produced by underwater blast and the complex pressure history exposures experienced by aggregates encased within a sphere and subjected to simulated air blast. The nature of blast-induced primary TBI requires a multidisciplinary research approach that addresses the fidelity of the blast insult, its accurate measurement and characterization, as well as the limitations of the biological models used.

30 CFR 75.1323 - Blasting circuits.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Blasting circuits shall be protected from sources of stray electric current. (b) Detonators made by...) Each wire connection in a blasting circuit shall be— (1) Properly spliced; and (2) Separated from other connections in the circuit to prevent accidental contact and arcing. (h) Uninsulated connections in each...

30 CFR 75.1323 - Blasting circuits.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Blasting circuits shall be protected from sources of stray electric current. (b) Detonators made by...) Each wire connection in a blasting circuit shall be— (1) Properly spliced; and (2) Separated from other connections in the circuit to prevent accidental contact and arcing. (h) Uninsulated connections in each...

Acceleration from short-duration blast

NASA Astrophysics Data System (ADS)

Ritzel, D. V.; Van Albert, S.; Sajja, V.; Long, J.

2018-01-01

The blast-induced motion of spheres has been studied experimentally where the shock wave is rapidly decaying during the period that quasi-steady acceleration would be developed in the case of a step-function shock wave as considered in most shock-tube studies. The motion of sphere models ranging from 39 to 251 mm in diameter and having a range of densities was assessed using the "free-flight" method in a simulator specially designed to replicate the decaying shock wave profile of spherical blast including negative phase and positive entropy gradient. A standardized blast-wave simulation of 125 kPa and 6-ms positive-phase duration was applied for all experiments. In all cases, there are three phases to the motion: a relatively low "kickoff" velocity from the shock diffraction, acceleration or deceleration during the positive duration, then deceleration through the negative phase and subsequent quiescent air. The unexpected deceleration of larger spheres after their kickoff velocity during the decaying yet high-speed flow of the blast wave seems associated with the persistence of a ring vortex on the downstream side of the sphere. The flow is entirely unsteady with initial forces dominated by the shock diffraction; therefore, the early motion of spheres under such conditions is not governed by quasi-steady drag as in classical aerodynamics. The work will help establish scaling rules for model studies of blast-induced motion relevant to improvised explosive devices, and preliminary results are shown for motion imparted to a human skull surrogate.

Prevention of Blast-Related Injuries

DTIC Science & Technology

2015-07-14

pathology of traumatic axonal injury involves distinct injury processes, neurofilament compaction (NFC) and impaired axoplasmic transport (IAT)1. In rat...assessments and may render diagnosis of blast related pathology even more difficult. These neuronal injury changes in the grey matter that appeared...were from blast studies using rodents16,17 and impulse noise18. A putative pathological implication for microglia comes from studies by Kane et al

Note: A table-top blast driven shock tube

NASA Astrophysics Data System (ADS)

Courtney, Michael W.; Courtney, Amy C.

2010-12-01

The prevalence of blast-induced traumatic brain injury in conflicts in Iraq and Afghanistan has motivated laboratory scale experiments on biomedical effects of blast waves and studies of blast wave transmission properties of various materials in hopes of improving armor design to mitigate these injuries. This paper describes the design and performance of a table-top shock tube that is more convenient and widely accessible than traditional compression driven and blast driven shock tubes. The design is simple: it is an explosive driven shock tube employing a rifle primer that explodes when impacted by the firing pin. The firearm barrel acts as the shock tube, and the shock wave emerges from the muzzle. The small size of this shock tube can facilitate localized application of a blast wave to a subject, tissue, or material under test.

Note: A table-top blast driven shock tube.

PubMed

Courtney, Michael W; Courtney, Amy C

2010-12-01

The prevalence of blast-induced traumatic brain injury in conflicts in Iraq and Afghanistan has motivated laboratory scale experiments on biomedical effects of blast waves and studies of blast wave transmission properties of various materials in hopes of improving armor design to mitigate these injuries. This paper describes the design and performance of a table-top shock tube that is more convenient and widely accessible than traditional compression driven and blast driven shock tubes. The design is simple: it is an explosive driven shock tube employing a rifle primer that explodes when impacted by the firing pin. The firearm barrel acts as the shock tube, and the shock wave emerges from the muzzle. The small size of this shock tube can facilitate localized application of a blast wave to a subject, tissue, or material under test.

Information modeling system for blast furnace control

NASA Astrophysics Data System (ADS)

Spirin, N. A.; Gileva, L. Y.; Lavrov, V. V.

2016-09-01

Modern Iron & Steel Works as a rule are equipped with powerful distributed control systems (DCS) and databases. Implementation of DSC system solves the problem of storage, control, protection, entry, editing and retrieving of information as well as generation of required reporting data. The most advanced and promising approach is to use decision support information technologies based on a complex of mathematical models. The model decision support system for control of blast furnace smelting is designed and operated. The basis of the model system is a complex of mathematical models created using the principle of natural mathematical modeling. This principle provides for construction of mathematical models of two levels. The first level model is a basic state model which makes it possible to assess the vector of system parameters using field data and blast furnace operation results. It is also used to calculate the adjustment (adaptation) coefficients of the predictive block of the system. The second-level model is a predictive model designed to assess the design parameters of the blast furnace process when there are changes in melting conditions relative to its current state. Tasks for which software is developed are described. Characteristics of the main subsystems of the blast furnace process as an object of modeling and control - thermal state of the furnace, blast, gas dynamic and slag conditions of blast furnace smelting - are presented.

A Life Study of Ausforged, Standard Forged and Standard Machined AISI M-50 Spur Gears

NASA Technical Reports Server (NTRS)

Townsend, D. P.; Bamberger, E. N.; Zaretsky, E. V.

1975-01-01

Tests were conducted at 350 K (170 F) with three groups of 8.9 cm (3.5 in.) pitch diameter spur gears made of vacuum induction melted (VIM) consumable-electrode vacuum-arc melted (VAR), AISI M-50 steel and one group of vacuum-arc remelted (VAR) AISI 9310 steel. The pitting fatigue life of the standard forged and ausforged gears was approximately five times that of the VAR AISI 9310 gears and ten times that of the bending fatigue life of the standard machined VIM-VAR AISI M-50 gears run under identical conditions. There was a slight decrease in the 10-percent life of the ausforged gears from that for the standard forged gears, but the difference is not statistically significant. The standard machined gears failed primarily by gear tooth fracture while the forged and ausforged VIM-VAR AISI M-50 and the VAR AISI 9310 gears failed primarily by surface pitting fatigue. The ausforged gears had a slightly greater tendency to fail by tooth fracture than the standard forged gears.

30 CFR 56.6312 - Secondary blasting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Explosives Use § 56.6312 Secondary blasting. Secondary blasts fired at the same time in the same work area shall be initiated from...

Micro-blast waves using detonation transmission tubing

NASA Astrophysics Data System (ADS)

Samuelraj, I. Obed; Jagadeesh, G.; Kontis, K.

2013-07-01

Micro-blast waves emerging from the open end of a detonation transmission tube were experimentally visualized in this study. A commercially available detonation transmission tube was used (Nonel tube, M/s Dyno Nobel, Sweden), which is a small diameter tube coated with a thin layer of explosive mixture (HMX + traces of Al) on its inner side. The typical explosive loading for this tube is of the order of 18 mg/m of tube length. The blast wave was visualized using a high speed digital camera (frame rate 1 MHz) to acquire time-resolved schlieren images of the resulting flow field. The visualization studies were complemented by computational fluid dynamic simulations. An analysis of the schlieren images showed that although the blast wave appears to be spherical, it propagates faster along the tube axis than along a direction perpendicular to the tube axis. Additionally, CFD analysis revealed the presence of a barrel shock and Mach disc, showing structures that are typical of an underexpanded jet. A theory in use for centered large-scale explosions of intermediate strength (10 < Δ {p}/{p}_0 ≲ 0.02) gave good agreement with the blast trajectory along the tube axis. The energy of these micro-blast waves was found to be 1.25 ± 0.94 J and the average TNT equivalent was found to be 0.3. The repeatability in generating these micro-blast waves using the Nonel tube was very good (± 2 %) and this opens up the possibility of using this device for studying some of the phenomena associated with muzzle blasts in the near future.

ISRU Soil Mechanics Vacuum Facility: Soil Bin Preparation and Simulant Strength Characterization

NASA Technical Reports Server (NTRS)

Kleinhenz, Julie; Wilkinson, Allen

2012-01-01

Testing in relevant environments is key to exploration mission hardware development. This is true on both the component level (in early development) and system level (in late development stages). During ISRU missions the hardware will interface with the soil (digging, roving, etc) in a vacuum environment. A relevant test environment will therefore involve a vacuum chamber with a controlled, conditioned simulant bed. However, in earth-based granular media, such as lunar soil simulant, gases trapped within the material pore structures and water adsorbed to all particle surfaces will release when exposed to vacuum. Early vacuum testing has shown that this gas release can occur violently, which loosens and weakens the simulant, altering the consolidation state. The Vacuum Facility #13, a mid-size chamber (3.66m tall, 1.5m inner diameter) at the NASA Glenn Research Center has been modified to create a soil mechanics test facility. A 0.64m deep by 0.914m square metric ton bed of lunar simulant was placed under vacuum using a variety of pumping techniques. Both GRC-3 and LHT-3M simulant types have been used. An electric cone penetrometer was used to measure simulant strength properties at vacuum including: cohesion, friction angle, bulk density and shear modulus. Simulant disruptions, caused by off gassing, affected the strength properties, but could be mitigated by reducing pump rate. No disruptions were observed at pressures below 2.5Torr, regardless of the pump rate. However, slow off gassing of the soil lead to long test times, a full week, to reach 10-5Torr. This work highlights the need for robotic machine-simulant hardware and operations in vacuum to expeditiously perform (sub-)systems tests.

Application of Carbon Composite Bricks for Blast Furnace Hearth

NASA Astrophysics Data System (ADS)

Zuo, Haibin; Wang, Cong; Zhang, Jianliang; Zhao, Yongan; Jiao, Kexin

Traditional refractory materials for blast furnace hearth lining are mainly composed of carbon bricks and the ceramic cup. However, these materials can't meet the demands for long service life design of blast furnaces. In this paper, a new refractory called carbon composite brick (CCB) was introduced, which combined the advantages of carbon bricks and the ceramic cup. In this case, the resistance of the CCB against corrosion was equal to the ceramic cup and the thermal conductivity of the CCB was equal to carbon bricks. From the results of more than 20 blast furnaces, the CCB could be well used in small blast furnaces and large blast furnaces. In the bad condition of low grade burden and high smelting intensity, the CCB gave full play to the role of cooling system, and effectively resisted the erosion of hot metal to improve the service life of blast furnaces.

Low-Cost, Rugged High-Vacuum System

NASA Technical Reports Server (NTRS)

Sorensen, Paul; Kline-Schoder, Robert

2012-01-01

A need exists for miniaturized, rugged, low-cost high-vacuum systems. Recent advances in sensor technology have led to the development of very small mass spectrometer detectors as well as other analytical instruments such as scanning electron microscopes. However, the vacuum systems to support these sensors remain large, heavy, and power-hungry. To meet this need, a miniaturized vacuum system was developed based on a very small, rugged, and inexpensive-to-manufacture molecular drag pump (MDP). The MDP is enabled by a miniature, very-high-speed (200,000 rpm), rugged, low-power, brushless DC motor optimized for wide temperature operation and long life. The key advantages of the pump are reduced cost and improved ruggedness compared to other mechanical hig-hvacuum pumps. The machining of the rotor and stators is very simple compared to that necessary to fabricate rotor and stator blades for other pump designs. Also, the symmetry of the rotor is such that dynamic balancing of the rotor will likely not be necessary. Finally, the number of parts in the unit is cut by nearly a factor of three over competing designs. The new pump forms the heart of a complete vacuum system optimized to support analytical instruments in terrestrial applications and on spacecraft and planetary landers. The MDP achieves high vacuum coupled to a ruggedized diaphragm rough pump. Instead of the relatively complicated rotor and stator blades used in turbomolecular pumps, the rotor in the MDP consists of a simple, smooth cylinder of aluminum. This will turn at approximately 200,000 rpm inside an outer stator housing. The pump stator comprises a cylindrical aluminum housing with one or more specially designed grooves that serve as flow channels. To minimize the length of the pump, the gas is forced down the flow channels of the outer stator to the base of the pump. The gas is then turned and pulled toward the top through a second set of channels cut into an inner stator housing that surrounds the

Numerical Study of the Reduction Process in an Oxygen Blast Furnace

NASA Astrophysics Data System (ADS)

Zhang, Zongliang; Meng, Jiale; Guo, Lei; Guo, Zhancheng

2016-02-01

Based on computational fluid dynamics, chemical reaction kinetics, principles of transfer in metallurgy, and other principles, a multi-fluid model for a traditional blast furnace was established. The furnace conditions were simulated with this multi-fluid mathematical model, and the model was verified with the comparison of calculation and measurement. Then a multi-fluid model for an oxygen blast furnace in the gasifier-full oxygen blast furnace process was established based on this traditional blast furnace model. With the established multi-fluid model for an oxygen blast furnace, the basic characteristics of iron ore reduction process in the oxygen blast furnace were summarized, including the changing process of the iron ore reduction degree and the compositions of the burden, etc. The study found that compared to the traditional blast furnace, the magnetite reserve zone in the furnace shaft under oxygen blast furnace condition was significantly reduced, which is conducive to the efficient operation of blast furnace. In order to optimize the oxygen blast furnace design and operating parameters, the iron ore reduction process in the oxygen blast furnace was researched under different shaft tuyere positions, different recycling gas temperatures, and different allocation ratios of recycling gas between the hearth tuyere and the shaft tuyere. The results indicate that these three factors all have a substantial impact on the ore reduction process in the oxygen blast furnace. Moderate shaft tuyere position, high recycling gas temperature, and high recycling gas allocation ratio between hearth and shaft could significantly promote the reduction of iron ore, reduce the scope of the magnetite reserve zone, and improve the performance of oxygen blast furnace. Based on the above findings, the recommendations for improvement of the oxygen blast furnace design and operation were proposed.

Quantitative electroencephalography in a swine model of blast-induced brain injury.

PubMed

Chen, Chaoyang; Zhou, Chengpeng; Cavanaugh, John M; Kallakuri, Srinivasu; Desai, Alok; Zhang, Liying; King, Albert I

2017-01-01

Electroencephalography (EEG) was used to examine brain activity abnormalities earlier after blast exposure using a swine model to develop a qEEG data analysis protocol. Anaesthetized swine were exposed to 420-450 Kpa blast overpressure and survived for 3 days after blast. EEG recordings were performed at 15 minutes before the blast and 15 minutes, 30 minutes, 2 hours and 1, 2 and 3 days post-blast using surface recording electrodes and a Biopac 4-channel data acquisition system. Off-line quantitative EEG (qEEG) data analysis was performed to determine qEEG changes. Blast induced qEEG changes earlier after blast exposure, including a decrease of mean amplitude (MAMP), an increase of delta band power, a decrease of alpha band root mean square (RMS) and a decrease of 90% spectral edge frequency (SEF90). This study demonstrated that qEEG is sensitive for cerebral injury. The changes of qEEG earlier after the blast indicate the potential of utilization of multiple parameters of qEEG for diagnosis of blast-induced brain injury. Early detection of blast induced brain injury will allow early screening and assessment of brain abnormalities in soldiers to enable timely therapeutic intervention.

Vacuum mechatronics

NASA Technical Reports Server (NTRS)

Hackwood, Susan; Belinski, Steven E.; Beni, Gerardo

1989-01-01

The discipline of vacuum mechatronics is defined as the design and development of vacuum-compatible computer-controlled mechanisms for manipulating, sensing and testing in a vacuum environment. The importance of vacuum mechatronics is growing with an increased application of vacuum in space studies and in manufacturing for material processing, medicine, microelectronics, emission studies, lyophylisation, freeze drying and packaging. The quickly developing field of vacuum mechatronics will also be the driving force for the realization of an advanced era of totally enclosed clean manufacturing cells. High technology manufacturing has increasingly demanding requirements for precision manipulation, in situ process monitoring and contamination-free environments. To remove the contamination problems associated with human workers, the tendency in many manufacturing processes is to move towards total automation. This will become a requirement in the near future for e.g., microelectronics manufacturing. Automation in ultra-clean manufacturing environments is evolving into the concept of self-contained and fully enclosed manufacturing. A Self Contained Automated Robotic Factory (SCARF) is being developed as a flexible research facility for totally enclosed manufacturing. The construction and successful operation of a SCARF will provide a novel, flexible, self-contained, clean, vacuum manufacturing environment. SCARF also requires very high reliability and intelligent control. The trends in vacuum mechatronics and some of the key research issues are reviewed.

Application of AI techniques to blast furnace operations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Iida, Osamu; Ushijima, Yuichi; Sawada, Toshiro

1995-10-01

It was during the first stages of application of artificial intelligence (AI) to industrial fields, that the ironmaking division of Mizushima works at Kawasaki Steel recognized its potential. Since that time, the division has sought applications for these techniques to solve various problems. AI techniques applied to control the No. 3 blast furnace operations at the Mizushima works include: Blast furnace control by a diagnostic type of expert system that gives guidance to the actions required for blast furnace operation as well as control of furnace heat by automatically setting blast temperature; Hot stove combustion control by a combination ofmore » fuzzy inference and a physical model to insure good thermal efficiency of the stove; and blast furnace burden control using neural networks makes it possible to connect the pattern of gas flow distribution with the condition of the furnace. Experience of AI to control the blast furnace and other ironmaking operations has proved its capability for achieving automation and increased operating efficiency. The benefits are very high. For these reasons, the applications of AI techniques will be extended in the future and new techniques studied to further improve the power of AI.« less

The quinary pattern of blast injury.

PubMed

Kluger, Yoram; Nimrod, Adi; Biderman, Philippe; Mayo, Ami; Sorkin, Patric

2007-01-01

Bombing is the primary weapon of global terrorism, and it results in a complicated, multidimensional injury pattern. It induces bodily injuries through the well-documented primary, secondary, tertiary, and quaternary mechanisms of blast. Their effects dictate special medical concern and timely implementation of diagnostic and management strategies. Our objective is to report on clinical observations of patients admitted to the Tel Aviv Medical Center following a terrorist bombing. The explosion injured 27 patients, and three died. Four survivors who had been in close proximity to the explosion, as indicated by their eardrum perforation and additional blast injuries, were exposed to the blast wave. They exhibited a unique and immediate hyperinflammatory state, two upon admission to the intensive care unit and two during surgery. This hyperinflammatory state manifested as hyperpyrexia, sweating, low central venous pressure, and positive fluid balance. This state did not correlate with the complexity of injuries sustained by any of the 67 patients admitted to the intensive care unit after previous bombings. The patients' hyperinflammatory behavior, unrelated to their injury complexity and severity of trauma, indicates a new injury pattern in explosions, termed the "quinary blast injury pattern." Unconventional materials used in the manufacture of the explosive can partly explain the observed early hyperinflammatory state. Medical personnel caring for blast victims should be aware of this new type of bombing injury.

Micro Machining of Injection Mold Inserts for Fluidic Channel of Polymeric Biochips

PubMed Central

Jung, Woo-Chul; Heo, Young-Moo; Yoon, Gil-Sang; Shin, Kwang-Ho; Chang, Sung-Ho; Kim, Gun-Hee; Cho, Myeong-Woo

2007-01-01

Recently, the polymeric micro-fluidic biochip, often called LOC (lab-on-a-chip), has been focused as a cheap, rapid and simplified method to replace the existing biochemical laboratory works. It becomes possible to form miniaturized lab functionalities on a chip with the development of MEMS technologies. The micro-fluidic chips contain many micro-channels for the flow of sample and reagents, mixing, and detection tasks. Typical substrate materials for the chip are glass and polymers. Typical techniques for microfluidic chip fabrication are utilizing various micro pattern forming methods, such as wet-etching, micro-contact printing, and hot-embossing, micro injection molding, LIGA, and micro powder blasting processes, etc. In this study, to establish the basis of the micro pattern fabrication and mass production of polymeric micro-fluidic chips using injection molding process, micro machining method was applied to form micro-channels on the LOC molds. In the research, a series of machining experiments using micro end-mills were performed to determine optimum machining conditions to improve surface roughness and shape accuracy of designed simplified micro-channels. Obtained conditions were used to machine required mold inserts for micro-channels using micro end-mills. Test injection processes using machined molds and COC polymer were performed, and then the results were investigated.

Tritium release from SS316 under vacuum condition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Torikai, Y.; Penzhorn, R.D.

The plasma facing surface of the ITER vacuum vessel, partly made of low carbon austenitic stainless steel type 316L, will incorporate tritium during machine operation. In this paper the kinetics of tritium release from stainless steel type 316 into vacuum and into a noble gas stream are compared and modelled. Type 316 stainless steel specimens loaded with tritium either by exposure to 1.2 kPa HT at 573 K or submersion into liquid HTO at 298 K showed characteristic thin surface layers trapping tritium in concentrations far higher than those determined in the bulk. The evolution of the tritium depth profilemore » in the bulk during heating under vacuum was non-discernible from that of tritium liberated into a stream of argon. Only the relative amount of the two released tritium-species, i.e. HT or HTO, was different. Temperature-dependent depth profiles could be predicted with a one-dimensional diffusion model. Diffusion coefficients derived from fitting of the tritium release into an evacuated vessel or a stream of argon were found to be (1.4 ± 1.0)*10{sup -7} and (1.3 ± 0.9)*10{sup -9} cm{sup 2}/s at 573 and 423 K, respectively. Polished surfaces on type SS316 stainless steel inhibit considerably the thermal release rate of tritium.« less

Comprehensive Numerical Modeling of the Blast Furnace Ironmaking Process

NASA Astrophysics Data System (ADS)

Zhou, Chenn; Tang, Guangwu; Wang, Jichao; Fu, Dong; Okosun, Tyamo; Silaen, Armin; Wu, Bin

2016-05-01

Blast furnaces are counter-current chemical reactors, widely utilized in the ironmaking industry. Hot reduction gases injected from lower regions of the furnace ascend, reacting with the descending burden. Through this reaction process, iron ore is reduced into liquid iron that is tapped from the furnace hearth. Due to the extremely harsh environment inside the blast furnace, it is difficult to measure or observe internal phenomena during operation. Through the collaboration between steel companies and the Center for Innovation through Visualization and Simulation, multiple computational fluid dynamics (CFD) models have been developed to simulate the complex multiphase reacting flow in the three regions of the furnace, the shaft, the raceway, and the hearth. The models have been used effectively to troubleshoot and optimize blast furnace operations. In addition, the CFD models have been integrated with virtual reality. An interactive virtual blast furnace has been developed for training purpose. This paper summarizes the developments and applications of blast furnace CFD models and the virtual blast furnace.

Survey of rice blast race identity for blast resistance gene identification in the USA and Puerto Rico

USDA-ARS?s Scientific Manuscript database

Rice blast disease is a significant threat to stable rice production in the USA and worldwide. The major resistance gene (Pi-ta) located within a cluster of resistance genes on rice chromosome 12 has been demonstrated to confer resistance to the rice blast disease. Katy, a rice cultivar released in ...

Blasting and Passivation Treatments for ASTM F139 Stainless Steel for Biomedical Applications: Effects on Surface Roughness, Hardening, and Localized Corrosion

NASA Astrophysics Data System (ADS)

Barboza, Adriana L. Lemos; Kang, Kyung Won; Bonetto, Rita D.; Llorente, Carlos L.; Bilmes, Pablo D.; Gervasi, Claudio A.

2015-01-01

Due to the combination of good biofunctionality and biocompatibility at low cost, AISI 316 low carbon vacuum melting (LVM) stainless steel, as considered in ASTM F139 standard, is often the first choice for medical implants, particularly for use in orthopedic surgery. Proper surface finish must be provided to ensure adequate interactions of the alloy with human body tissues that in turn allows the material to deliver the desired performance. Preliminary studies performed in our laboratory on AISI 316LVM stainless steel surfaces modified by glass bead blasting (from industrial supplier) followed by different nitric acid passivation conditions disclosed the necessity to extend parameters of the surface treatments and to further consider roughness, pitting corrosion resistance, and surface and subsurface hardening measurements, all in one, as the most effective characterization strategy. This was the approach adopted in the present work. Roughness assessment was performed by means of amplitude parameters, functional parameters, and an estimator of the fractal dimension that characterizes surface topography. We clearly demonstrate that the blasting treatment should be carried out under controlled conditions in order to obtain similar surface and subsurface properties. Otherwise, a variation in one of the parameters could modify the surface properties, exerting a profound impact on its application as biomaterial. A passivation step is necessary to offset the detrimental effect of blasting on pitting corrosion resistance.

Natural vacuum electronics

NASA Technical Reports Server (NTRS)

Leggett, Nickolaus

1990-01-01

The ambient natural vacuum of space is proposed as a basis for electron valves. Each valve is an electron controlling structure similiar to a vacuum tube that is operated without a vacuum sustaining envelope. The natural vacuum electron valves discussed offer a viable substitute for solid state devices. The natural vacuum valve is highly resistant to ionizing radiation, system generated electromagnetic pulse, current transients, and direct exposure to space conditions.

Close-in Blast Waves from Spherical Charges*

NASA Astrophysics Data System (ADS)

Howard, William; Kuhl, Allen

2011-06-01

We study the close-in blast waves created by the detonation of spherical high explosives (HE) charges, via numerical simulations with our Arbitrary-Lagrange-Eulerian (ALE3D) code. We used a finely-resolved, fixed Eulerian 2-D mesh (200 μm per cell) to capture the detonation of the charge, the blast wave propagation in air, and the reflection of the blast wave from an ideal surface. The thermodynamic properties of the detonation products and air were specified by the Cheetah code. A programmed-burn model was used to detonate the charge at a rate based on measured detonation velocities. The results were analyzed to evaluate the: (i) free air pressure-range curves: Δps (R) , (ii) free air impulse curves, (iii) reflected pressure-range curves, and (iv) reflected impulse-range curves. A variety of explosives were studied. Conclusions are: (i) close-in (R < 10 cm /g 1 / 3) , each explosive had its own (unique) blast wave (e.g., Δps (R , HE) ~ a /Rn , where n is different for each explosive); (ii) these close-in blast waves do not scale with the ``Heat of Detonation'' of the explosive (because close-in, there is not enough time to fully couple the chemical energy to the air via piston work); (iii) instead they are related to the detonation conditions inside the charge. Scaling laws will be proposed for such close-in blast waves.

Modelling and Testing of Blast Effect On the Structures

NASA Astrophysics Data System (ADS)

Figuli, Lucia; Jangl, Štefan; Papán, Daniel

2016-10-01

As a blasting agent in the blasting and mining engineering, has been using one of so called new generation of explosives which offer greater flexibility in their range and application, and such explosive is ANFO. It is type of explosive consists of an oxidiser and a fuel (ammonium nitrate and fuel oil). One of such ANFO explosives which are industrially made in Slovakia is POLONIT. The explosive is a mixture of ammonium nitrate, methyl esters of higher fatty acids, vegetable oil and red dye. The paper deals with the analysis of structure subjected to the blast load created by the explosion of POLONIT charge. First part of paper is describing behaviour and characteristic of blast wave generated from the blast (detonation characteristics, physical characteristics, time-history diagram etc.) and the second part presents the behaviour of such loaded structures, because of the analysis of such dynamical loaded structure is required knowing the parameters of blast wave, its effect on structure and the tools for the solution of dynamic analysis. The real field tests of three different weight of charges and two different structures were done. The explosive POLONIT was used together with 25 g of ignition explosive PLNp10. Analytical and numerical model of blast loaded structure is compared with the results obtained from the field tests (is compared with the corresponding experimental accelerations). For the modelling structures were approximated as a one-degree system of freedom (SDOF), where the blast wave was estimated with linear decay and exponential decay using positive and negative phase of blast wave. Numerical solution of the steel beam dynamic response was performed via FEM (Finite Element Method) using standard software Visual FEA.

VACUUM TRAP

DOEpatents

Gordon, H.S.

1959-09-15

An improved adsorption vacuum trap for use in vacuum systems was designed. The distinguishing feature is the placement of a plurality of torsionally deformed metallic fins within a vacuum jacket extending from the walls to the central axis so that substantially all gas molecules pass through the jacket will impinge upon the fin surfaces. T fins are heated by direct metallic conduction, thereby ol taining a uniform temperature at the adeorbing surfaces so that essentially all of the condensible impurities from the evacuating gas are removed from the vacuum system.

Blast Injury: Translating Research Into Operational Medicine (Preprint)

DTIC Science & Technology

2008-05-20

i Blast Injury: Translating Research into Operational Medicine Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for...SUBTITLE Blast Injury: Translating Research Into Operational Medicine 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...Z39-18 iii Blast Injury: Translating Research into Operational Medicine Preprint BI-QP-JHS-CH10 Borden Institute This chapter was originally

Requirements for CEC POP Machine Protection System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pinayev, I.

2015-02-18

The requirements of CEC POP machine protection system are meant to prevent damage to a vacuum chamber by a missteered electron beam. In this example, beam energy = 22 MeV, Maximal bunch charge = 5 nC, Maximal repetition rate = 78 kHz, Normalized emittance = 5 mm mrad, Minimal β-function = 1 m. From this information the requirements of the protection system can be calculated by factoring the information into equations to find beam densities and temperature excursions.

On the Interaction and Coalescence if Spherical Blast Waves

NASA Technical Reports Server (NTRS)

Kandula, Max; Freeman, Robert J.

2005-01-01

The scaling and similarity laws concerning the propagation of isolated spherical blast waves are briefly reviewed. Both point source explosions and high pressure gas explosions are considered. Test data on blast overpressure from the interaction and coalescence of spherical blast waves emanating from explosives in the form of shaped charges of different strength placed in the vicinity of a solid propellant stack are presented. These data are discussed with regard to the scaling laws concerning the decay of blast overpressure. The results point out the possibility of detecting source explosions from far-field pressure measurements.

Determination of Destress Blasting Effectiveness Using Seismic Source Parameters

NASA Astrophysics Data System (ADS)

Wojtecki, Łukasz; Mendecki, Maciej J.; Zuberek, Wacaław M.

2017-12-01

Underground mining of coal seams in the Upper Silesian Coal Basin is currently performed under difficult geological and mining conditions. The mining depth, dislocations (faults and folds) and mining remnants are responsible for rockburst hazard in the highest degree. This hazard can be minimized by using active rockburst prevention, where destress blastings play an important role. Destress blastings in coal seams aim to destress the local stress concentrations. These blastings are usually performed from the longwall face to decrease the stress level ahead of the longwall. An accurate estimation of active rockburst prevention effectiveness is important during mining under disadvantageous geological and mining conditions, which affect the risk of rockburst. Seismic source parameters characterize the focus of tremor, which may be useful in estimating the destress blasting effects. Investigated destress blastings were performed in coal seam no. 507 during its longwall mining in one of the coal mines in the Upper Silesian Coal Basin under difficult geological and mining conditions. The seismic source parameters of the provoked tremors were calculated. The presented preliminary investigations enable a rapid estimation of the destress blasting effectiveness using seismic source parameters, but further analysis in other geological and mining conditions with other blasting parameters is required.

Computational modeling of blast exposure associated with recoilless weapons combat training

NASA Astrophysics Data System (ADS)

Wiri, S.; Ritter, A. C.; Bailie, J. M.; Needham, C.; Duckworth, J. L.

2017-11-01

Military personnel are exposed to blast as part of routine combat training with shoulder-fired recoilless rifles. These weapons fire large-caliber ammunitions capable of disabling structures and uparmored vehicles (e.g., tanks). Scientific, medical, and military leaders are beginning to recognize the blast overpressure from these shoulder-fired weapons may result in acute and even long-term physiological effects to military personnel. However, the back blast generated from the Carl Gustav and Shoulder-launched Multipurpose Assault Weapon (SMAW) shoulder-fired weapons on the weapon operator has not been quantified. By quantifying and modeling the full-body blast exposure from these weapons, better injury correlations can be constructed. Blast exposure data from the Carl Gustav and SMAW were used to calibrate a propellant burn source term for computational simulations of blast exposure on operators of these shoulder-mounted weapon systems. A propellant burn model provided the source term for each weapon to capture blast effects. Blast data from personnel-mounted gauges during weapon firing were used to create initial, high-fidelity 3D computational fluid dynamic simulations using SHAMRC (Second-order Hydrodynamic Automatic Mesh Refinement Code). These models were then improved upon using data collected from static blast sensors positioned around the military personnel while weapons were utilized in actual combat training. The final simulation models for both the Carl Gustav and SMAW were in good agreement with the data collected from the personnel-mounted and static pressure gauges. Using the final simulation results, contour maps were created for peak overpressure and peak overpressure impulse experienced by military personnel firing the weapon as well as those assisting with firing of those weapons. Reconstruction of the full-body blast loading enables a more accurate assessment of the cause of potential mechanisms of injury due to air blast even for subjects not

Enhancing cuttings removal with gas blasts while drilling on Mars

NASA Astrophysics Data System (ADS)

Zacny, K. A.; Quayle, M. C.; Cooper, G. A.

2005-04-01

Future missions to Mars envision use of drills for subsurface exploration. Since the Martian atmosphere precludes the use of liquids for cuttings removal, proposed drilling machines utilize mechanical cuttings removal systems such as augers. However, an auger can substantially contribute to the total power requirements, and in the worst scenario it can choke. A number of experiments conducted under Martian pressures showed that intermittent blasts of gas at low differential pressures can effectively lift the cuttings out of the hole. A gas flushing system could be incorporated into the drill assembly for assistance in clearing the holes of rock cuttings or for redundancy in case of auger jamming. A number of variables such as the particle size distribution of the rock powder, the type of gas used, the bit and auger side clearances, the initial mass of cuttings, and the ambient pressure were investigated and found to affect the efficiency. In all tests the initial volume of gas was close to 1 L and the differential pressure was varied to achieve desired clearing efficiencies. Particles were being lifted out of the hole at a maximum speed of 6 m/s at a differential pressure of 25 torr and ambient pressure of 5 torr. Flushing tests lasted on average for 2 s. The power required to compress the thin Martian atmosphere to achieve a sufficient gas blast every minute or so at 10% efficiency was calculated to be of the order of a few watts.

Blasting response of the Eiffel Tower

NASA Astrophysics Data System (ADS)

Horlyck, Lachlan; Hayes, Kieran; Caetano, Ryan; Tahmasebinia, Faham; Ansourian, Peter; Alonso-Marroquin, Fernando

2016-08-01

A finite element model of the Eiffel Tower was constructed using Strand7 software. The model replicates the existing tower, with dimensions justified through the use of original design drawings. A static and dynamic analysis was conducted to determine the actions of the tower under permanent, imposed and wind loadings, as well as under blast pressure loads and earthquake loads due to an explosion. It was observed that the tower utilises the full axial capacity of individual members by acting as a `truss of trusses'. As such, permanent and imposed loads are efficiently transferred to the primary columns through compression, while wind loads induce tensile forces in the windward legs and compressive forces in the leeward. Under blast loading, the tower experienced both ground vibrations and blast pressures. Ground vibrations induced a negligibly small earthquake loading into the structure which was ignored in subsequent analyses. The blast pressure was significant, and a dynamic analysis of this revealed that further research is required into the damping qualities of the structure due to soil and mechanical properties. In the worst case scenario, the blast was assumed to completely destroy several members in the adjacent leg. Despite this weakened condition, it was observed that the tower would still be able to sustain static loads, at least for enough time for occupant evacuation. Further, an optimised design revealed the structure was structurally sound under a 46% reduction of the metal tower's mass.

Mechanisms of Hearing Loss after Blast Injury to the Ear

PubMed Central

Cho, Sung-Il; Gao, Simon S.; Xia, Anping; Wang, Rosalie; Salles, Felipe T.; Raphael, Patrick D.; Abaya, Homer; Wachtel, Jacqueline; Baek, Jongmin; Jacobs, David; Rasband, Matthew N.; Oghalai, John S.

2013-01-01

Given the frequent use of improvised explosive devices (IEDs) around the world, the study of traumatic blast injuries is of increasing interest. The ear is the most common organ affected by blast injury because it is the body’s most sensitive pressure transducer. We fabricated a blast chamber to re-create blast profiles similar to that of IEDs and used it to develop a reproducible mouse model to study blast-induced hearing loss. The tympanic membrane was perforated in all mice after blast exposure and found to heal spontaneously. Micro-computed tomography demonstrated no evidence for middle ear or otic capsule injuries; however, the healed tympanic membrane was thickened. Auditory brainstem response and distortion product otoacoustic emission threshold shifts were found to be correlated with blast intensity. As well, these threshold shifts were larger than those found in control mice that underwent surgical perforation of their tympanic membranes, indicating cochlear trauma. Histological studies one week and three months after the blast demonstrated no disruption or damage to the intra-cochlear membranes. However, there was loss of outer hair cells (OHCs) within the basal turn of the cochlea and decreased spiral ganglion neurons (SGNs) and afferent nerve synapses. Using our mouse model that recapitulates human IED exposure, our results identify that the mechanisms underlying blast-induced hearing loss does not include gross membranous rupture as is commonly believed. Instead, there is both OHC and SGN loss that produce auditory dysfunction. PMID:23840874

Intense X-ray machine for penetrating radiography

NASA Astrophysics Data System (ADS)

Lucht, Roy A.; Eckhouse, Shimon

Penetrating radiography has been used for many years in the nuclear weapons research programs. Infrequently penetrating radiography has been used in conventional weapons research programs. For example the Los Alamos PHERMEX machine was used to view uranium rods penetrating steel for the GAU-8 program, and the Ector machine was used to see low density regions in forming metal jets. The armor/anti-armor program at Los Alamos has created a need for an intense flash X-ray machine that can be dedicated to conventional weapons research. The Balanced Technology Initiative, through DARPA, has funded the design and construction of such a machine at Los Alamos. It will be an 8- to 10-MeV diode machine capable of delivering a dose of 500 R at 1 m with a spot size of less than 5 mm. The machine used an 87.5-stage low inductance Marx generator that charges up a 7.4-(Omega), 32-ns water line. The water line is discharged through a self-breakdown oil switch into a 12.4-(Omega) water line that rings up the voltage into the high impendance X-ray diode. A long (233-cm) vacuum drift tube is used to separate the large diameter oil-insulated diode region from the X-ray source area that may be exposed to high overpressures by the explosive experiments. The electron beam is selffocused at the target area using a low pressure background gas.

30 CFR 57.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Extraneous Electricity-Surface and Underground § 57.6605 Isolation of blasting circuits. Lead wires and... shall be protected from sources of stray or static electricity. Blasting circuits shall be protected...

30 CFR 57.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Extraneous Electricity-Surface and Underground § 57.6605 Isolation of blasting circuits. Lead wires and... shall be protected from sources of stray or static electricity. Blasting circuits shall be protected...

30 CFR 57.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Extraneous Electricity-Surface and Underground § 57.6605 Isolation of blasting circuits. Lead wires and... shall be protected from sources of stray or static electricity. Blasting circuits shall be protected...

30 CFR 57.6605 - Isolation of blasting circuits.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Extraneous Electricity-Surface and Underground § 57.6605 Isolation of blasting circuits. Lead wires and... shall be protected from sources of stray or static electricity. Blasting circuits shall be protected...

Lateral blasts at Mount St. Helens and hazard zonation

USGS Publications Warehouse

Crandell, D.R.; Hoblitt, R.P.

1986-01-01

Lateral blasts at andesitic and dacitic volcanoes can produce a variety of direct hazards, including ballistic projectiles which can be thrown to distances of at least 10 km and pyroclastic density flows which can travel at high speed to distances of more than 30 km. Indirect effect that may accompany such explosions include wind-borne ash, pyroclastic flows formed by the remobilization of rock debris thrown onto sloping ground, and lahars. Two lateral blasts occurred at a lava dome on the north flank of Mount St. Helens about 1200 years ago; the more energetic of these threw rock debris northeastward across a sector of about 30?? to a distance of at least 10 km. The ballistic debris fell onto an area estimated to be 50 km2, and wind-transported ash and lapilli derived from the lateral-blast cloud fell on an additional lobate area of at least 200 km2. In contrast, the vastly larger lateral blast of May 18, 1980, created a devastating pyroclastic density flow that covered a sector of as much as 180??, reached a maximum distance of 28 km, and within a few minutes directly affected an area of about 550 km2. The May 18 lateral blast resulted from the sudden, landslide-induced depressurization of a dacite cryptodome and the hydrothermal system that surrounded it within the volcano. We propose that lateral-blast hazard assessments for lava domes include an adjoining hazard zone with a radius of at least 10 km. Although a lateral blast can occur on any side of a dome, the sector directly affected by any one blast probably will be less than 180??. Nevertheless, a circular hazard zone centered on the dome is suggested because of the difficulty of predicting the direction of a lateral blast. For the purpose of long-term land-use planning, a hazard assessment for lateral blasts caused by explosions of magma bodies or pressurized hydrothermal systems within a symmetrical volcano could designate a circular potential hazard area with a radius of 35 km centered on the volcano

30 CFR 77.1304 - Blasting agents; special provisions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ammonium nitrate blasting agents, and the components thereof prior to mixing, shall be mixed and stored in... Sensitized Ammonium Nitrate Blasting Agents,” or subsequent revisions. (b) Where pneumatic loading is...

30 CFR 77.1304 - Blasting agents; special provisions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ammonium nitrate blasting agents, and the components thereof prior to mixing, shall be mixed and stored in... Sensitized Ammonium Nitrate Blasting Agents,” or subsequent revisions. (b) Where pneumatic loading is...

30 CFR 77.1304 - Blasting agents; special provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ammonium nitrate blasting agents, and the components thereof prior to mixing, shall be mixed and stored in... Sensitized Ammonium Nitrate Blasting Agents,” or subsequent revisions. (b) Where pneumatic loading is...

Shock Initiated Reactions of Reactive Multiphase Blast Explosives

NASA Astrophysics Data System (ADS)

Wilson, Dennis; Granier, John; Johnson, Richard; Littrell, Donald

2015-06-01

This paper describes a new class of reactive multiphase blast explosives (RMBX) and characterization of their blast characteristics. These RMBXs are non-ideal explosive compositions of perfluoropolyether (PFPE), nano aluminum, and a micron-size high-density reactive metal - Tantalum, Zirconium, or Zinc in mass loadings of 66 to 83 percent. Unlike high explosives, these PFPE-metal compositions release energy via a fast self-oxidized combustion wave (rather than a true self-sustaining detonation) that is shock dependent, and can be overdriven to control energy release rate. The term ``reactive multiphase blast'' refers to the post-dispersion blast behavior: multiphase in that there are a gas phase that imparts pressure and a solid (particulate) phase that imparts momentum; and reactive in that the hot metal particles react with atmospheric oxygen and the explosive gas products to give an extended pressure pulse. The RMBX formulations were tested in two spherical core-shell geometries - an RMBX shell exploded by a high explosive core, and an RMBX core imploded by a high explosive shell. The fireball and blast characteristics were compared to a C-4 baseline charge.

Explosively driven air blast in a conical shock tube

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stewart, Joel B., E-mail: joel.b.stewart2.civ@mail.mil; Pecora, Collin, E-mail: collin.r.pecora.civ@mail.mil

2015-03-15

Explosively driven shock tubes present challenges in terms of safety concerns and expensive upkeep of test facilities but provide more realistic approximations to the air blast resulting from free-field detonations than those provided by gas-driven shock tubes. Likewise, the geometry of conical shock tubes can naturally approximate a sector cut from a spherically symmetric blast, leading to a better agreement with the blast profiles of free-field detonations when compared to those provided by shock tubes employing constant cross sections. The work presented in this article documents the design, fabrication, and testing of an explosively driven conical shock tube whose goalmore » was to closely replicate the blast profile seen from a larger, free-field detonation. By constraining the blast through a finite area, large blasts (which can add significant damage and safety constraints) can be simulated using smaller explosive charges. The experimental data presented herein show that a close approximation to the free-field air blast profile due to a 1.5 lb charge of C4 at 76 in. can be achieved by using a 0.032 lb charge in a 76-in.-long conical shock tube (which translates to an amplification factor of nearly 50). Modeling and simulation tools were used extensively in designing this shock tube to minimize expensive fabrication costs.« less

30 CFR 75.1326 - Examination after blasting.

Code of Federal Regulations, 2010 CFR

2010-07-01

....1326 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Explosives and Blasting § 75.1326 Examination... and dust. (b) Immediately after the blasting area has cleared, a qualified person or a person working...

Seismic safety in conducting large-scale blasts

NASA Astrophysics Data System (ADS)

Mashukov, I. V.; Chaplygin, V. V.; Domanov, V. P.; Semin, A. A.; Klimkin, M. A.

2017-09-01

In mining enterprises to prepare hard rocks for excavation a drilling and blasting method is used. With the approach of mining operations to settlements the negative effect of large-scale blasts increases. To assess the level of seismic impact of large-scale blasts the scientific staff of Siberian State Industrial University carried out expertise for coal mines and iron ore enterprises. Determination of the magnitude of surface seismic vibrations caused by mass explosions was performed using seismic receivers, an analog-digital converter with recording on a laptop. The registration results of surface seismic vibrations during production of more than 280 large-scale blasts at 17 mining enterprises in 22 settlements are presented. The maximum velocity values of the Earth’s surface vibrations are determined. The safety evaluation of seismic effect was carried out according to the permissible value of vibration velocity. For cases with exceedance of permissible values recommendations were developed to reduce the level of seismic impact.

Blasting, graphical interfaces and Unix

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knudsen, S.; Preece, D.S.

1993-11-01

A discrete element computer program, DMC (Distinct Motion Code) was developed to simulate blast-induced rock motion. To simplify the complex task of entering material and explosive design parameters as well as bench configuration, a full-featured graphical interface has been developed. DMC is currently executed on both Sun SPARCstation 2 and Sun SPARCstation 10 platforms and routinely used to model bench and crater blasting problems. This paper will document the design and development of the full-featured interface to DMC. The development of the interface will be tracked through the various stages, highlighting the adjustments made to allow the necessary parameters tomore » be entered in terms and units that field blasters understand. The paper also discusses a novel way of entering non-integer numbers and the techniques necessary to display blasting parameters in an understandable visual manner. A video presentation will demonstrate the graphics interface and explains its use.« less

Blasting, graphical interfaces and Unix

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knudsen, S.; Preece, D.S.

1994-12-31

A discrete element computer program, DMC (Distinct Motion Code) was developed to simulate blast-induced rock motion. To simplify the complex task of entering material and explosive design parameters as well as bench configuration, a full-featured graphical interface has been developed. DMC is currently executed on both Sun SPARCstation 2 and Sun SPARCstation 10 platforms and routinely used to model bench and crater blasting problems. This paper will document the design and development of the full-featured interface to DMC. The development of the interface will be tracked through the various stages, highlighting the adjustments made to allow the necessary parameters tomore » be entered in terms and units that field blasters understand. The paper also discusses a novel way of entering non-integer numbers and the techniques necessary to display blasting parameters in an understandable visual manner. A video presentation will demonstrate the graphics interface and explains its use.« less

Comparison of vacuum and non-vacuum urine tubes for urinary sediment analysis.

PubMed

Topcuoglu, Canan; Sezer, Sevilay; Kosem, Arzu; Ercan, Mujgan; Turhan, Turan

2017-12-01

Urine collection systems with aspiration system for vacuum tubes are becoming increasingly common for urinalysis, especially for microscopic examination of the urine. In this study, we aimed to examine whether vacuum aspiration of the urine sample has any adverse effect on sediment analysis by comparing results from vacuum and non-vacuum urine tubes. The study included totally 213 urine samples obtained from inpatients and outpatients in our hospital. Urine samples were collected to containers with aspiration system for vacuum tubes. Each sample was aliquoted to both vacuum and non-vacuum urine tubes. Urinary sediment analysis was performed using manual microscope. Results were evaluated using chi-square test. Comparison of the sediment analysis results from vacuum and non-vacuum urine tubes showed that results were highly concordant for erythrocyte, leukocyte and epithelial cells (gamma values 1, 0.997, and 0.994, respectively; p < .001). Results were also concordant for urinary casts, crystals and yeast (kappa values 0.815, 0.945 and 1, respectively; p < .001). The results show that in urinary sediment analysis, vacuum aspiration has no adverse effect on the cellular components except on casts.

H-BLAST: a fast protein sequence alignment toolkit on heterogeneous computers with GPUs.

PubMed

Ye, Weicai; Chen, Ying; Zhang, Yongdong; Xu, Yuesheng

2017-04-15

The sequence alignment is a fundamental problem in bioinformatics. BLAST is a routinely used tool for this purpose with over 118 000 citations in the past two decades. As the size of bio-sequence databases grows exponentially, the computational speed of alignment softwares must be improved. We develop the heterogeneous BLAST (H-BLAST), a fast parallel search tool for a heterogeneous computer that couples CPUs and GPUs, to accelerate BLASTX and BLASTP-basic tools of NCBI-BLAST. H-BLAST employs a locally decoupled seed-extension algorithm for better performance on GPUs, and offers a performance tuning mechanism for better efficiency among various CPUs and GPUs combinations. H-BLAST produces identical alignment results as NCBI-BLAST and its computational speed is much faster than that of NCBI-BLAST. Speedups achieved by H-BLAST over sequential NCBI-BLASTP (resp. NCBI-BLASTX) range mostly from 4 to 10 (resp. 5 to 7.2). With 2 CPU threads and 2 GPUs, H-BLAST can be faster than 16-threaded NCBI-BLASTX. Furthermore, H-BLAST is 1.5-4 times faster than GPU-BLAST. https://github.com/Yeyke/H-BLAST.git. yux06@syr.edu. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

Highly concentrated foam formulation for blast mitigation

DOEpatents

Tucker, Mark D.; Gao, Huizhen

2010-12-14

A highly concentrated foam formulation for blast suppression and dispersion mitigation for use in responding to a terrorism incident involving a radiological dispersion device. The foam formulation is more concentrated and more stable than the current blast suppression foam (AFC-380), which reduces the logistics burden on the user.

Blast overpressure after tire explosion: a fatal case.

PubMed

Pomara, Cristoforo; D'Errico, Stefano; Riezzo, Irene; Perilli, Gabriela; Volpe, Umberto; Fineschi, Vittorio

2013-12-01

Fatal blast injuries are generally reported in literature as a consequence of the detonation of explosives in war settings. The pattern of lesion depends on the position of the victim in relation to the explosion, on whether the blast tracks through air or water, and whether it happens in the open air or within an enclosed space and the distance from the explosion. Tire explosion-related injuries are rarely reported in literature. This study presents a fatal case of blast overpressure due to the accidental explosion of a truck tire occurring in a tire repair shop. A multidisciplinary approach to the fatality involving forensic pathologists and engineers revealed that the accidental explosion, which caused a series of primary and tertiary blast wave injuries, was due to tire deterioration.

Characterising the acceleration phase of blast wave formation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fox, T. E., E-mail: tef503@york.ac.uk; Pasley, J.; Central Laser Facility, STFC Rutherford Appleton Laboratory, Harwell Oxford, Didcot OX11 0QX

2014-10-15

Intensely heated, localised regions in uniform fluids will rapidly expand and generate an outwardly propagating blast wave. The Sedov-Taylor self-similar solution for such blast waves has long been studied and applied to a variety of scenarios. A characteristic time for their formation has also long been identified using dimensional analysis, which by its very nature, can offer several interpretations. We propose that, rather than simply being a characteristic time, it may be interpreted as the definitive time taken for a blast wave resulting from an intense explosion in a uniform media to contain its maximum kinetic energy. A scaling relationmore » for this measure of the acceleration phase, preceding the establishment of the blast wave, is presented and confirmed using a 1D planar hydrodynamic model.« less

Bomb blast mass casualty incidents: initial triage and management of injuries.

PubMed

Goh, S H

2009-01-01

Bomb blast injuries are no longer confined to battlefields. With the ever present threat of terrorism, we should always be prepared for bomb blasts. Bomb blast injuries tend to affect air-containing organs more, as the blast wave tends to exert a shearing force on air-tissue interfaces. Commonly-injured organs include the tympanic membranes, the sinuses, the lungs and the bowel. Of these, blast lung injury is the most challenging to treat. The clinical picture is a mix of acute respiratory distress syndrome and air embolism, and the institution of positive pressure ventilation in the presence of low venous pressures could cause systemic arterial air embolism. The presence of a tympanic membrane perforation is not a reliable indicator of the presence of a blast injury in the other air-containing organs elsewhere. Radiological imaging of the head, chest and abdomen help with the early identification of blast lung injury, head injury, abdominal injury, eye and sinus injuries, as well as any penetration by foreign bodies. In addition, it must be borne in mind that bomb blasts could also be used to disperse radiological and chemical agents.

Reconstruction of improvised explosive device blast loading to personnel in the open

NASA Astrophysics Data System (ADS)

Wiri, Suthee; Needham, Charles

2016-05-01

Significant advances in reconstructing attacks by improvised explosive devices (IEDs) and other blast events are reported. A high-fidelity three-dimensional computational fluid dynamics tool, called Second-order Hydrodynamic Automatic Mesh Refinement Code, was used for the analysis. Computer-aided design models for subjects or vehicles in the scene accurately represent geometries of objects in the blast field. A wide range of scenario types and blast exposure levels were reconstructed including free field blast, enclosed space of vehicle cabin, IED attack on a vehicle, buried charges, recoilless rifle operation, rocket-propelled grenade attack and missile attack with single subject or multiple subject exposure to pressure levels from ˜ 27.6 kPa (˜ 4 psi) to greater than 690 kPa (>100 psi). To create a full 3D pressure time-resolved reconstruction of a blast event for injury and blast exposure analysis, a combination of intelligence data and Blast Gauge data can be used to reconstruct an actual in-theatre blast event. The methodology to reconstruct an event and the "lessons learned" from multiple reconstructions in open space are presented. The analysis uses records of blast pressure at discrete points, and the output is a spatial and temporal blast load distribution for all personnel involved.

Lasting Retinal Injury in a Mouse Model of Blast-Induced Trauma.

PubMed

Mammadova, Najiba; Ghaisas, Shivani; Zenitsky, Gary; Sakaguchi, Donald S; Kanthasamy, Anumantha G; Greenlee, Justin J; West Greenlee, M Heather

2017-07-01

Traumatic brain injury due to blast exposure is currently the most prevalent of war injuries. Although secondary ocular blast injuries due to flying debris are more common, primary ocular blast exposure resulting from blast wave pressure has been reported among survivors of explosions, but with limited understanding of the resulting retinal pathologies. Using a compressed air-driven shock tube system, adult male and female C57BL/6 mice were exposed to blast wave pressure of 300 kPa (43.5 psi) per day for 3 successive days, and euthanized 30 days after injury. We assessed retinal tissues using immunofluorescence for glial fibrillary acidic protein, microglia-specific proteins Iba1 and CD68, and phosphorylated tau (AT-270 pThr181 and AT-180 pThr231). Primary blast wave pressure resulted in activation of Müller glia, loss of photoreceptor cells, and an increase in phosphorylated tau in retinal neurons and glia. We found that 300-kPa blasts yielded no detectable cognitive or motor deficits, and no neurochemical or biochemical evidence of injury in the striatum or prefrontal cortex, respectively. These changes were detected 30 days after blast exposure, suggesting the possibility of long-lasting retinal injury and neuronal inflammation after primary blast exposure. Copyright © 2017 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

Primary blast-induced traumatic brain injury: lessons from lithotripsy

NASA Astrophysics Data System (ADS)

Nakagawa, A.; Ohtani, K.; Armonda, R.; Tomita, H.; Sakuma, A.; Mugikura, S.; Takayama, K.; Kushimoto, S.; Tominaga, T.

2017-11-01

Traumatic injury caused by explosive or blast events is traditionally divided into four mechanisms: primary, secondary, tertiary, and quaternary blast injury. The mechanisms of blast-induced traumatic brain injury (bTBI) are biomechanically distinct and can be modeled in both in vivo and in vitro systems. The primary bTBI injury mechanism is associated with the response of brain tissue to the initial blast wave. Among the four mechanisms of bTBI, there is a remarkable lack of information regarding the mechanism of primary bTBI. On the other hand, 30 years of research on the medical application of shock waves (SWs) has given us insight into the mechanisms of tissue and cellular damage in bTBI, including both air-mediated and underwater SW sources. From a basic physics perspective, the typical blast wave consists of a lead SW followed by shock-accelerated flow. The resultant tissue injury includes several features observed in primary bTBI, such as hemorrhage, edema, pseudo-aneurysm formation, vasoconstriction, and induction of apoptosis. These are well-described pathological findings within the SW literature. Acoustic impedance mismatch, penetration of tissue by shock/bubble interaction, geometry of the skull, shear stress, tensile stress, and subsequent cavitation formation are all important factors in determining the extent of SW-induced tissue and cellular injury. In addition, neuropsychiatric aspects of blast events need to be taken into account, as evidenced by reports of comorbidity and of some similar symptoms between physical injury resulting in bTBI and the psychiatric sequelae of post-traumatic stress. Research into blast injury biophysics is important to elucidate specific pathophysiologic mechanisms of blast injury, which enable accurate differential diagnosis, as well as development of effective treatments. Herein we describe the requirements for an adequate experimental setup when investigating blast-induced tissue and cellular injury; review SW physics

29 CFR 1926.906 - Initiation of explosive charges-electric blasting.

Code of Federal Regulations, 2010 CFR

2010-07-01

... dangerous. Blasting cap leg wires shall be kept short-circuited (shunted) until they are connected into the..., in accordance with the manufacturer's recommendations. (f) Connecting wires and lead wires shall be... manufacturer of the electric blasting caps used. (o) The number of electric blasting caps connected to a...

Evaluation of Blast Resistance of Fiber Reinforced Composite Specimens under Contact Blast Load

NASA Astrophysics Data System (ADS)

Janota, O.; Foglar, M.

2017-09-01

This paper presents results of experimental programme which took place in 2014, 2015 and 2016. Experiments were focused on the resistance of full scale concrete panels subjected to contact blast loading. Specimens were loaded by contact blast by plastic explosive. All specimens were reinforced concrete slabs made of fiber concrete. Basalt mesh and textile sheets were added to some of the experiments for creating more heterogeneous material to achieve better resistance of the specimens. Evaluation of experiments was mainly focused on the damaged area on the contact side and soffit of the specimens. Dependency of the final damage of concrete panels on the weight of explosive and concrete strength was assessed.

Computerized Machine for Cutting Space Shuttle Thermal Tiles

NASA Technical Reports Server (NTRS)

Ramirez, Luis E.; Reuter, Lisa A.

2009-01-01

A report presents the concept of a machine aboard the space shuttle that would cut oversized thermal-tile blanks to precise sizes and shapes needed to replace tiles that were damaged or lost during ascent to orbit. The machine would include a computer-controlled jigsaw enclosed in a clear acrylic shell that would prevent escape of cutting debris. A vacuum motor would collect the debris into a reservoir and would hold a tile blank securely in place. A database stored in the computer would contain the unique shape and dimensions of every tile. Once a broken or missing tile was identified, its identification number would be entered into the computer, wherein the cutting pattern associated with that number would be retrieved from the database. A tile blank would be locked into a crib in the machine, the shell would be closed (proximity sensors would prevent activation of the machine while the shell was open), and a "cut" command would be sent from the computer. A blade would be moved around the crib like a plotter, cutting the tile to the required size and shape. Once the tile was cut, an astronaut would take a space walk for installation.

Blasting Damage Predictions by Numerical Modeling in Siahbishe Pumped Storage Powerhouse

NASA Astrophysics Data System (ADS)

Eslami, Majid; Goshtasbi, Kamran

2018-04-01

One of the popular methods of underground and surface excavations is the use of blasting. Throughout this method of excavation, the loading resulted from blasting can be affected by different geo-mechanical and structural parameters of rock mass. Several factors affect turbulence in underground structures some of which are explosion, vibration, and stress impulses caused by the neighbouring blasting products. In investigating the blasting mechanism one should address the processes which expand with time and cause seismic events. To protect the adjoining structures against any probable deconstruction or damage, it is very important to model the blasting process prior to any actual operation. Efforts have been taken in the present study to demonstrate the potentiality of numerical methods in predicting the specified parameters in order to prevent any probable destruction. For this purpose the blasting process was modeled, according to its natural implementation, in one of the tunnels of Siahbishe dam by the 3DEC and AUTODYN 3D codes. 3DEC was used for modeling the blasting environment as well as the blast holes and AUTODYN 3D for modeling the explosion process in the blast hole. In this process the output of AUTODYN 3D, which is a result of modeling the blast hole and is in the form of stress waves, is entered into 3DEC. For analyzing the amount of destruction made by the blasting operation, the key parameter of Peak Particle Velocity was used. In the end, the numerical modeling results have been compared with the data recorded by the seismographs planted through the tunnel. As the results indicated 3DEC and AUTODYN 3D proved appropriate for analyzing such an issue. Therefore, by means of these two softwares one can analyze explosion processes prior to their implementation and make close estimation of the damage resulting from these processes.

49 CFR 570.56 - Vacuum brake assist unit and vacuum brake system.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... The following requirements apply to vehicles with vacuum brake assist units and vacuum brake systems. (a) Vacuum brake assist unit integrity. The vacuum brake assist unit shall demonstrate integrity as... maintained on the pedal. (1) Inspection procedure. Stop the engine and apply service brake several times to...

A Multi-Mode Shock Tube for Investigation of Blast-Induced Traumatic Brain Injury

PubMed Central

Reneer, Dexter V.; Hisel, Richard D.; Hoffman, Joshua M.; Kryscio, Richard J.; Lusk, Braden T.

2011-01-01

Abstract Blast-induced mild traumatic brain injury (bTBI) has become increasingly common in recent military conflicts. The mechanisms by which non-impact blast exposure results in bTBI are incompletely understood. Current small animal bTBI models predominantly utilize compressed air-driven membrane rupture as their blast wave source, while large animal models use chemical explosives. The pressure-time signature of each blast mode is unique, making it difficult to evaluate the contributions of the different components of the blast wave to bTBI when using a single blast source. We utilized a multi-mode shock tube, the McMillan blast device, capable of utilizing compressed air- and compressed helium-driven membrane rupture, and the explosives oxyhydrogen and cyclotrimethylenetrinitramine (RDX, the primary component of C-4 plastic explosives) as the driving source. At similar maximal blast overpressures, the positive pressure phase of compressed air-driven blasts was longer, and the positive impulse was greater, than those observed for shockwaves produced by other driving sources. Helium-driven shockwaves more closely resembled RDX blasts, but by displacing air created a hypoxic environment within the shock tube. Pressure-time traces from oxyhydrogen-driven shockwaves were very similar those produced by RDX, although they resulted in elevated carbon monoxide levels due to combustion of the polyethylene bag used to contain the gases within the shock tube prior to detonation. Rats exposed to compressed air-driven blasts had more pronounced vascular damage than those exposed to oxyhydrogen-driven blasts of the same peak overpressure, indicating that differences in blast wave characteristics other than peak overpressure may influence the extent of bTBI. Use of this multi-mode shock tube in small animal models will enable comparison of the extent of brain injury with the pressure-time signature produced using each blast mode, facilitating evaluation of the blast wave

A multi-mode shock tube for investigation of blast-induced traumatic brain injury.

PubMed

Reneer, Dexter V; Hisel, Richard D; Hoffman, Joshua M; Kryscio, Richard J; Lusk, Braden T; Geddes, James W

2011-01-01

Blast-induced mild traumatic brain injury (bTBI) has become increasingly common in recent military conflicts. The mechanisms by which non-impact blast exposure results in bTBI are incompletely understood. Current small animal bTBI models predominantly utilize compressed air-driven membrane rupture as their blast wave source, while large animal models use chemical explosives. The pressure-time signature of each blast mode is unique, making it difficult to evaluate the contributions of the different components of the blast wave to bTBI when using a single blast source. We utilized a multi-mode shock tube, the McMillan blast device, capable of utilizing compressed air- and compressed helium-driven membrane rupture, and the explosives oxyhydrogen and cyclotrimethylenetrinitramine (RDX, the primary component of C-4 plastic explosives) as the driving source. At similar maximal blast overpressures, the positive pressure phase of compressed air-driven blasts was longer, and the positive impulse was greater, than those observed for shockwaves produced by other driving sources. Helium-driven shockwaves more closely resembled RDX blasts, but by displacing air created a hypoxic environment within the shock tube. Pressure-time traces from oxyhydrogen-driven shockwaves were very similar those produced by RDX, although they resulted in elevated carbon monoxide levels due to combustion of the polyethylene bag used to contain the gases within the shock tube prior to detonation. Rats exposed to compressed air-driven blasts had more pronounced vascular damage than those exposed to oxyhydrogen-driven blasts of the same peak overpressure, indicating that differences in blast wave characteristics other than peak overpressure may influence the extent of bTBI. Use of this multi-mode shock tube in small animal models will enable comparison of the extent of brain injury with the pressure-time signature produced using each blast mode, facilitating evaluation of the blast wave components

Demonstrations with a Vacuum: Old Demonstrations for New Vacuum Pumps.

ERIC Educational Resources Information Center

Greenslade, Thomas B., Jr.

1989-01-01

Explains mechanisms of 19th-century vacuum pumps. Describes demonstrations using the pump including guinea and feather tube, aurora tube, electric egg, Gassiots cascade, air mill, bell in vacuum, density and buoyancy of air, fountain in vacuum, mercury shower, palm and bladder glasses, Bacchus demonstration, pneumatic man-lifter, and Magdeburg…

Lightweight Energy Absorbers for Blast Containers

NASA Technical Reports Server (NTRS)

Balles, Donald L.; Ingram, Thomas M.; Novak, Howard L.; Schricker, Albert F.

2003-01-01

Kinetic-energy-absorbing liners made of aluminum foam have been developed to replace solid lead liners in blast containers on the aft skirt of the solid rocket booster of the space shuttle. The blast containers are used to safely trap the debris from small explosions that are initiated at liftoff to sever frangible nuts on hold-down studs that secure the spacecraft to a mobile launch platform until liftoff.

Mine Blast Loading: Experiments and Simulations

DTIC Science & Technology

2010-04-01

plates by approximately 50%. We investigated the root cause for this discrepancy. The simulations calculate a turbulent-like flow field characterized...Toussaint [19] evaluated two numerical methods, Smooth Particle Hydrodynamics ( SPH ) and Arbitrary Lagrangian Eulerian (ALE), to simulate a mine blast on...That is, the mine blast products were not flowing along the solid plate boundary in the simulations as freely as they should. 6 In particular, the V

Vascular and Inflammatory Factors in the Pathophysiology of Blast-Induced Brain Injury

PubMed Central

Elder, Gregory A.; Gama Sosa, Miguel A.; De Gasperi, Rita; Stone, James Radford; Dickstein, Dara L.; Haghighi, Fatemeh; Hof, Patrick R.; Ahlers, Stephen T.

2015-01-01

Blast-related traumatic brain injury (TBI) has received much recent attention because of its frequency in the conflicts in Iraq and Afghanistan. This renewed interest has led to a rapid expansion of clinical and animal studies related to blast. In humans, high-level blast exposure is associated with a prominent hemorrhagic component. In animal models, blast exerts a variety of effects on the nervous system including vascular and inflammatory effects that can be seen with even low-level blast exposures which produce minimal or no neuronal pathology. Acutely, blast exposure in animals causes prominent vasospasm and decreased cerebral blood flow along with blood-brain barrier breakdown and increased vascular permeability. Besides direct effects on the central nervous system, evidence supports a role for a thoracically mediated effect of blast; whereby, pressure waves transmitted through the systemic circulation damage the brain. Chronically, a vascular pathology has been observed that is associated with alterations of the vascular extracellular matrix. Sustained microglial and astroglial reactions occur after blast exposure. Markers of a central and peripheral inflammatory response are found for sustained periods after blast injury and include elevation of inflammatory cytokines and other inflammatory mediators. At low levels of blast exposure, a microvascular pathology has been observed in the presence of an otherwise normal brain parenchyma, suggesting that the vasculature may be selectively vulnerable to blast injury. Chronic immune activation in brain following vascular injury may lead to neurobehavioral changes in the absence of direct neuronal pathology. Strategies aimed at preventing or reversing vascular damage or modulating the immune response may improve the chronic neuropsychiatric symptoms associated with blast-related TBI. PMID:25852632

Storage stability of flour-blasted brown rice

USDA-ARS?s Scientific Manuscript database

Brown rice was blasted with rice flour rather than sand in a sand blaster to make microscopic nicks and cuts so that water can easily penetrate into the brown rice endosperm and cook the rice in a shorter time. The flour-blasted American Basmati brown rice, long grain brown rice, and parboiled long...

Evaluation of the Effectiveness of Wet Blast Cleaning Methods of Surface Preparation

DTIC Science & Technology

1985-06-01

for Air Abrasive Wet Blast: Complete System Water Abrasive Mixing Chamber in Slurry Blast Unit Schematic of unit Control Unit Slurry Blast — Air/Water...this discussion we present some general. user guidelines regarding what to look for in con- sidering the use or purchase of wet blasting equipment...These units use compressed air as the medium to propel the eroding material. They differ from air abrasive wet blast units in that the abrasive is mixed

The Pre-Blast Concept for use on Armour Materials

DTIC Science & Technology

2016-02-01

to improve blast resistance Repeated blast test results (up to 7 times) of candidate armour materials showed that the greatest deformation...may be used to increase blast resistance of steels. To test this, the ‘pre-blast’ concept test program includes hardening of materials by sheet charge...steels with hardness 450 HV or higher (up to 650 HV). In general, the improvement in deformation resistance is associated with increases in

PaperBLAST: Text Mining Papers for Information about Homologs.

PubMed

Price, Morgan N; Arkin, Adam P

2017-01-01

Large-scale genome sequencing has identified millions of protein-coding genes whose function is unknown. Many of these proteins are similar to characterized proteins from other organisms, but much of this information is missing from annotation databases and is hidden in the scientific literature. To make this information accessible, PaperBLAST uses EuropePMC to search the full text of scientific articles for references to genes. PaperBLAST also takes advantage of curated resources (Swiss-Prot, GeneRIF, and EcoCyc) that link protein sequences to scientific articles. PaperBLAST's database includes over 700,000 scientific articles that mention over 400,000 different proteins. Given a protein of interest, PaperBLAST quickly finds similar proteins that are discussed in the literature and presents snippets of text from relevant articles or from the curators. PaperBLAST is available at http://papers.genomics.lbl.gov/. IMPORTANCE With the recent explosion of genome sequencing data, there are now millions of uncharacterized proteins. If a scientist becomes interested in one of these proteins, it can be very difficult to find information as to its likely function. Often a protein whose sequence is similar, and which is likely to have a similar function, has been studied already, but this information is not available in any database. To help find articles about similar proteins, PaperBLAST searches the full text of scientific articles for protein identifiers or gene identifiers, and it links these articles to protein sequences. Then, given a protein of interest, it can quickly find similar proteins in its database by using standard software (BLAST), and it can show snippets of text from relevant papers. We hope that PaperBLAST will make it easier for biologists to predict proteins' functions.

13. BUILDING NO. 621, INTERIOR, TOP OF BLASTING TUB UNDERNEATH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. BUILDING NO. 621, INTERIOR, TOP OF BLASTING TUB UNDERNEATH SAWDUST HOPPER. BLASTING TUB HAS DOUBLE WALLS OF 3/4' THICK STEEL ARMOR PLATE. CHARGE TO BE TESTED IS BURIED IN SAWDUST WITH FLAME RESISTANT CHEMICALS. ELEVATOR BEHIND TUB CARRIES SAWDUST BACK TO TOP OF SAWDUST HOPPER AFTER TEST IS COMPLETED AND SAWDUST IN BLASTING TUB HAS BEEN SIFTED FOR SHELL FRAGMENTS. LOUVERS IN WALLS ARE HINGED FREELY SO THEY OPEN TO RELIEVE BLAST PRESSURE DURING A TEST. - Picatinny Arsenal, 600 Area, Test Areas District, State Route 15 near I-80, Dover, Morris County, NJ

REQUIREMENTS AND GUIDELINES FOR NSLS EXPERIMENTAL BEAM LINE VACUUM SYSTEMS-REVISION B.

DOE Office of Scientific and Technical Information (OSTI.GOV)

FOERSTER,C.

Typical beam lines are comprised of an assembly of vacuum valves and shutters referred to as a ''front end'', optical elements to monochromatize, focus and split the photon beam, and an experimental area where a target sample is placed into the photon beam and data from the interaction is detected and recorded. Windows are used to separate sections of beam lines that are not compatible with storage ring ultra high vacuum. Some experimental beam lines share a common vacuum with storage rings. Sections of beam lines are only allowed to vent up to atmospheric pressure using pure nitrogen gas aftermore » a vacuum barrier is established to protect ring vacuum. The front end may only be bled up when there is no current in the machine. This is especially true on the VUV storage ring where for most experiments, windows are not used. For the shorter wavelength, more energetic photons of the x-ray ring, beryllium windows are used at various beam line locations so that the monochromator, mirror box or sample chamber may be used in a helium atmosphere or rough vacuum. The window separates ring vacuum from the environment of the downstream beam line components. The stored beam lifetime in the storage rings and the maintenance of desirable reflection properties of optical surfaces depend upon hydrocarbon-free, ultra-high vacuum systems. Storage ring vacuum systems will operate at pressures of {approximately} 1 x 10{sup {minus}10} Torr without beam and {approximately} 1 x 10{sup {minus}9} Torr with beam. Systems are free of hydrocarbons in the sense that no pumps, valves, etc. containing organics are used. Components are all-metal, chemically cleaned and bakeable. To the extent that beam lines share a common vacuum with the storage ring, the same criteria will hold for beam line components. The design philosophy for NSLS beam lines is to use all-metal, hydrocarbon-free front end components and recommend that experimenters use this approach for common vacuum hardware downstream

Current advance methods for the identification of blast resistance genes in rice.

PubMed

Tanweer, Fatah A; Rafii, Mohd Y; Sijam, Kamaruzaman; Rahim, Harun A; Ahmed, Fahim; Latif, Mohammad A

2015-05-01

Rice blast caused by Magnaporthe oryzae is one of the most devastating diseases of rice around the world and crop losses due to blast are considerably high. Many blast resistant rice varieties have been developed by classical plant breeding and adopted by farmers in various rice-growing countries. However, the variability in the pathogenicity of the blast fungus according to environment made blast disease a major concern for farmers, which remains a threat to the rice industry. With the utilization of molecular techniques, plant breeders have improved rice production systems and minimized yield losses. In this article, we have summarized the current advanced molecular techniques used for controlling blast disease. With the advent of new technologies like marker-assisted selection, molecular mapping, map-based cloning, marker-assisted backcrossing and allele mining, breeders have identified more than 100 Pi loci and 350 QTL in rice genome responsible for blast disease. These Pi genes and QTLs can be introgressed into a blast-susceptible cultivar through marker-assisted backcross breeding. These molecular techniques provide timesaving, environment friendly and labour-cost-saving ways to control blast disease. The knowledge of host-plant interactions in the frame of blast disease will lead to develop resistant varieties in the future. Copyright © 2015 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Progress Toward Optimizing Prosthetic Socket Fit and Suspension Using Elevated Vacuum to Promote Residual Limb Health.

PubMed

Wernke, Matthew M; Schroeder, Ryan M; Haynes, Michael L; Nolt, Lonnie L; Albury, Alexander W; Colvin, James M

2017-07-01

Objective: Prosthetic sockets are custom made for each amputee, yet there are no quantitative tools to determine the appropriateness of socket fit. Ensuring a proper socket fit can have significant effects on the health of residual limb soft tissues and overall function and acceptance of the prosthetic limb. Previous work found that elevated vacuum pressure data can detect movement between the residual limb and the prosthetic socket; however, the correlation between the two was specific to each user. The overall objective of this work is to determine the relationship between elevated vacuum pressure deviations and prosthetic socket fit. Approach: A tension compression machine was used to apply repeated controlled forces onto a residual limb model with sockets of different internal volume. Results: The vacuum pressure-displacement relationship was dependent on socket fit. The vacuum pressure data were sensitive enough to detect differences of 1.5% global volume and can likely detect differences even smaller. Limb motion was reduced as surface area of contact between the limb model and socket was maximized. Innovation: The results suggest that elevated vacuum pressure data provide information to quantify socket fit. Conclusions: This study provides evidence that the use of elevated vacuum pressure data may provide a method for prosthetists to quantify and monitor socket fit. Future studies should investigate the relationship between socket fit, limb motion, and limb health to define optimal socket fit parameters.

Improved Vacuum Bazooka

NASA Astrophysics Data System (ADS)

Cockman, John

2003-04-01

This apparatus is a modification to the well-known "vacuum bazooka" (PIRA 2B30.70). My vacuum bazooka is easy to construct and demonstrate, requires no precise fittings, foil, or vacuum grease, and propels ping-pong balls at a tremendous velocity!

Off-center blast in a shocked medium

DOE PAGES

Duncan-Miller, Gabrielle Christiane; Stone, William D.

2017-11-16

When multiple blasts occur at different times, the situation arises in which a blast wave is propagating into a medium that has already been shocked. Determining the evolution in shape of the second shock is not trivial, as it is propagating into air that is not only non-uniform, but also non-stationary. To accomplish this task, we employ the method of Kompaneets to determine the shape of a shock in a non-uniform media. We also draw from the work of Korycansky [1] on an off-center explosion in a medium with radially varying density. Extending this to treat non-stationary flow, and makingmore » use of approximations to the Sedov solution for the point blast problem, we are able to determine an analytic expression for the evolving shape of the second shock. Specifically, we consider the case of a shock in air at standard ambient temperature and pressure, with the second shock occurring shortly after the original blast wave reaches it, as in a sympathetic detonation.« less

Off-center blast in a shocked medium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duncan-Miller, Gabrielle Christiane; Stone, William D.

When multiple blasts occur at different times, the situation arises in which a blast wave is propagating into a medium that has already been shocked. Determining the evolution in shape of the second shock is not trivial, as it is propagating into air that is not only non-uniform, but also non-stationary. To accomplish this task, we employ the method of Kompaneets to determine the shape of a shock in a non-uniform media. We also draw from the work of Korycansky [1] on an off-center explosion in a medium with radially varying density. Extending this to treat non-stationary flow, and makingmore » use of approximations to the Sedov solution for the point blast problem, we are able to determine an analytic expression for the evolving shape of the second shock. Specifically, we consider the case of a shock in air at standard ambient temperature and pressure, with the second shock occurring shortly after the original blast wave reaches it, as in a sympathetic detonation.« less

Blast-induced tinnitus and hyperactivity in the auditory cortex of rats.

PubMed

Luo, Hao; Pace, Edward; Zhang, Jinsheng

2017-01-06

Blast exposure can cause tinnitus and hearing impairment by damaging the auditory periphery and direct impact to the brain, which trigger neural plasticity in both auditory and non-auditory centers. However, the underlying neurophysiological mechanisms of blast-induced tinnitus are still unknown. In this study, we induced tinnitus in rats using blast exposure and investigated changes in spontaneous firing and bursting activity in the auditory cortex (AC) at one day, one month, and three months after blast exposure. Our results showed that spontaneous activity in the tinnitus-positive group began changing at one month after blast exposure, and manifested as robust hyperactivity at all frequency regions at three months after exposure. We also observed an increased bursting rate in the low-frequency region at one month after blast exposure and in all frequency regions at three months after exposure. Taken together, spontaneous firing and bursting activity in the AC played an important role in blast-induced chronic tinnitus as opposed to acute tinnitus, thus favoring a bottom-up mechanism. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

Characterization of Viscoelastic Materials for Low-Magnitude Blast Mitigation

NASA Astrophysics Data System (ADS)

Bartyczak, Susan; Mock, Willis

2013-06-01

Recent preliminary research indicates that exposure to low amplitude blast waves, such as from IED detonation or multiple firings of a weapon, causes damage to brain tissue resulting in Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD). Current combat helmets are not sufficiently protecting warfighters from this danger and the effects are debilitating, costly, and long-lasting. The objective of this research is to evaluate the blast mitigating behavior of current helmet materials and new materials designed for blast mitigation using a test fixture recently developed at the Naval Surface Warfare Center Dahlgren Division for use with an existing gas gun. A 40-mm-bore gas gun is used as a shock tube to generate blast waves (ranging from 5 to 30 psi) in a test fixture mounted at the gun muzzle. A fast opening valve is used to release helium gas from a breech which forms into a blast wave and impacts instrumented targets in the test fixture. Blast attenuation of selected materials is determined through the measurement of pressure and accelerometer data in front of and behind the target. Materials evaluated in this research include 6061-T6 aluminum, polyurea 1000, Styrofoam, and Sorbothane (durometer 50, shore 00). The experimental technique, calibration and checkout procedures, and results will be presented.

A new Wankel-type compressor and vacuum pump

NASA Astrophysics Data System (ADS)

Garside, D. W.

2017-08-01

When the Wankel principles were first published in the early 1950s most of the initial work was aimed at developing a compressor . At that time many of the characteristics appeared to promise a superior machine than hitherto known. However, all the early designs resulted in a high value for the minimum clearance volume (CV) and this problem was never overcome. Knowledge now gained from the development and manufacture of the Wankel engine has enabled the evolution of a new compressor concept where the rotor flank, radially very close-fitting over its central area, provides gas sealing with the housing bore. The rotor has an increased radial clearance towards the apices which makes the machine practical to manufacture. The ‘nesting’ of the rotor flank with the housing bore at the end of the exhaust stroke results in an extremely small CV. This machine promises to possess an exceptional combination of all the attributes which are important in achieving high energy efficiency in positive-displacement compressors and vacuum pumps: - near-zero CV - low mechanical friction losses - low internal gas leakage (assisted via oil flooding) - high volumetric efficiency. In addition it is compact, lightweight, vibration-free, consists of few components, and can be built in any chamber size. The Paper discusses the features and characteristics of the design.

A Mouse Model of Blast-Induced mild Traumatic Brain Injury

PubMed Central

Rubovitch, Vardit; Ten-Bosch, Meital; Zohar, Ofer; Harrison, Catherine R.; Tempel-Brami, Catherine; Stein, Elliot; Hoffer, Barry J.; Balaban, Carey D.; Schreiber, Shaul; Chiu, Wen-Ta; Pick, Chaim G.

2011-01-01

Improvised explosive devices (IEDs) are one of the main causes for casualties among civilians and military personnel in the present war against terror. Mild traumatic brain injury from IEDs induces various degrees of cognitive, emotional and behavioral disturbances but knowledge of the exact brain pathophysiology following exposure to blast is poorly understood. The study was aimed at establishing a murine model for a mild BI-TBI that isolates low-level blast pressure effects to the brain without systemic injuries. An open-field explosives detonation was used to replicate, as closely as possible, low-level blast trauma in the battlefield or at a terror-attack site. No alterations in basic neurological assessment or brain gross pathology were found acutely in the blast-exposed mice. At 7 days post blast, cognitive and behavioral tests revealed significantly decreased performance at both 4 and 7 meters distance from the blast (5.5 and 2.5 PSI, respectively). At 30 days post-blast, clear differences were found in animals at both distances in the object recognition test, and in the 7 m group in the Y maze test. Using MRI, T1 weighted images showed an increased BBB permeability one month post-blast. DTI analysis showed an increase in fractional anisotropy (FA) and a decrease in radial diffusivity. These changes correlated with sites of up-regulation of manganese superoxide dismutase 2 in neurons and CXC-motif chemokine receptor 3 around blood vessels in fiber tracts. These results may represent brain axonal and myelin abnormalities. Cellular and biochemical studies are underway in order to further correlate the blast-induced cognitive and behavioral changes and to identify possible underlying mechanisms that may help develop treatment- and neuroprotective modalities. PMID:21946269

Dynamic response analysis of surrounding rock under the continuous blasting seismic wave

NASA Astrophysics Data System (ADS)

Gao, P. F.; Zong, Q.; Xu, Y.; Fu, J.

2017-10-01

The blasting vibration that is caused by blasting excavation will generate a certain degree of negative effect on the stability of surrounding rock in underground engineering. A dynamic response analysis of surrounding rock under the continuous blasting seismic wave is carried out to optimize blasting parameters and guide underground engineering construction. Based on the theory of wavelet analysis, the reconstructed signals of each layer of different frequency bands are obtained by db8 wavelet decomposition. The difference of dynamic response of the continuous blasting seismic wave at a certain point caused by different blasting sources is discussed. The signal in the frequency band of natural frequency of the surrounding rock shows a certain degree of amplification effect deduced from the dynamic response characteristics of the surrounding rock under the influence of continuous blasting seismic wave. Continuous blasting operations in a fixed space will lead to the change of internal structure of the surrounding rock. It may result in the decline of natural frequency of the whole surrounding rock and it is also harmful for the stability of the surrounding rock.

Reduction of optically observed artillery blast wave trajectories using low dimensionality models

NASA Astrophysics Data System (ADS)

Steward, Bryan J.; Gross, Kevin C.; Perram, Glen P.

2011-05-01

Muzzle blast trajectories from firings of a 152 mm caliber gun howitzer were obtained with high-speed optical imagers and used to assess the fidelity with which low dimensionality models can be used for data reduction. Characteristic flow regions were defined for the blast waves. The near-field region was estimated to extend to 0.98 - 1.25 meters from the muzzle and the far-field region was estimated to begin at 2.61 - 3.31 meters. Blast wave geometries and radial trajectories were collected in the near through far-fields with visible imagers operating at 1,600 Hz. Beyond the near-field the blast waves exhibited a near-spherical geometry in which the major axis of the blast lay along the axis of the gun barrel and measured within 95% of the minor axis. Several blast wave propagation models were applied to the mid and far-field data to determine their ability to reduce the blast wave trajectories to fewer parameters while retaining the ability to distinguish amongst three munitions configurations. A total of 147 firings were observed and used to assess within-configuration variability relative to separation between configurations. Results show that all models perform well, and drag and point blast model parameters additionally provide insight into phenomenology of the blast.

Pneumatically Actuated Miniature Peristaltic Vacuum Pumps

NASA Technical Reports Server (NTRS)

Feldman, Sabrina; Feldman, Jason; Svehla, Danielle

2003-01-01

Pneumatically actuated miniature peristaltic vacuum pumps have been proposed for incorporation into advanced miniature versions of scientific instruments that depend on vacuum for proper operation. These pumps are expected to be capable of reaching vacuum-side pressures in the torr to millitorr range (from .133 down to .0.13 Pa). Vacuum pumps that operate in this range are often denoted roughing pumps. In comparison with previously available roughing pumps, these pumps are expected to be an order of magnitude less massive and less power-hungry. In addition, they would be extremely robust, and would operate with little or no maintenance and without need for oil or other lubricants. Portable mass spectrometers are typical examples of instruments that could incorporate the proposed pumps. In addition, the proposed pumps could be used as roughing pumps in general laboratory applications in which low pumping rates could be tolerated. The proposed pumps could be designed and fabricated in conventionally machined and micromachined versions. A typical micromachined version (see figure) would include a rigid glass, metal, or plastic substrate and two layers of silicone rubber. The bottom silicone layer would contain shallow pump channels covered by silicone arches that could be pushed down pneumatically to block the channels. The bottom silicone layer would be covered with a thin layer of material with very low gas permeability, and would be bonded to the substrate everywhere except in the channel areas. The top silicone layer would be attached to the bottom silicone layer and would contain pneumatic- actuation channels that would lie crosswise to the pump channels. This version is said to be micromachined because the two silicone layers containing the channels would be fabricated by casting silicone rubber on micromachined silicon molds. The pneumatic-actuation channels would be alternately connected to a compressed gas and (depending on pump design) either to atmospheric

High-fidelity simulations of blast loadings in urban environments using an overset meshing strategy

NASA Astrophysics Data System (ADS)

Wang, X.; Remotigue, M.; Arnoldus, Q.; Janus, M.; Luke, E.; Thompson, D.; Weed, R.; Bessette, G.

2017-05-01

Detailed blast propagation and evolution through multiple structures representing an urban environment were simulated using the code Loci/BLAST, which employs an overset meshing strategy. The use of overset meshes simplifies mesh generation by allowing meshes for individual component geometries to be generated independently. Detailed blast propagation and evolution through multiple structures, wave reflection and interaction between structures, and blast loadings on structures were simulated and analyzed. Predicted results showed good agreement with experimental data generated by the US Army Engineer Research and Development Center. Loci/BLAST results were also found to compare favorably to simulations obtained using the Second-Order Hydrodynamic Automatic Mesh Refinement Code (SHAMRC). The results obtained demonstrated that blast reflections in an urban setting significantly increased the blast loads on adjacent buildings. Correlations of computational results with experimental data yielded valuable insights into the physics of blast propagation, reflection, and interaction under an urban setting and verified the use of Loci/BLAST as a viable tool for urban blast analysis.

The Classical Vacuum.

ERIC Educational Resources Information Center

Boyer, Timothy H.

1985-01-01

The classical vacuum of physics is not empty, but contains a distinctive pattern of electromagnetic fields. Discovery of the vacuum, thermal spectrum, classical electron theory, zero-point spectrum, and effects of acceleration are discussed. Connection between thermal radiation and the classical vacuum reveals unexpected unity in the laws of…

Control technology for crystalline silica exposures in construction: wet abrasive blasting.

PubMed

Golla, Vijay; Heitbrink, William

2004-03-01

This study was designed to document the effect that wet abrasive blasting has on reducing worker exposure to crystalline silica, which has been associated with silicosis and premature death. In this study, worker exposure to respirable crystalline silica was monitored during wet abrasive blasting on the exterior walls of a parking garage to remove surface concrete and expose the underlying aggregate. In this process a wet sand mix comprised of 80% dry sand and 20% water was used. Sampling and analysis revealed that the geometric mean respirable quartz concentration was 0.2 mg/m(3) for workers conducting abrasive blasting and 0.06 mg/m(3) for helpers. When abrasive blasting was conducted in areas that apparently had reduced natural ventilation, dust exposures appeared to increase. When compared with other published data, this case study suggests that wet abrasive blasting causes less exposure to crystalline silica than dry abrasive blasting.

Electroweak vacuum instability and renormalized Higgs field vacuum fluctuations in the inflationary universe

NASA Astrophysics Data System (ADS)

Kohri, Kazunori; Matsui, Hiroki

2017-08-01

In this work, we investigated the electroweak vacuum instability during or after inflation. In the inflationary Universe, i.e., de Sitter space, the vacuum field fluctuations < δ phi 2 > enlarge in proportion to the Hubble scale H2. Therefore, the large inflationary vacuum fluctuations of the Higgs field < δ phi 2 > are potentially catastrophic to trigger the vacuum transition to the negative-energy Planck-scale vacuum state and cause an immediate collapse of the Universe. However, the vacuum field fluctuations < δ phi 2 >, i.e., the vacuum expectation values have an ultraviolet divergence, and therefore a renormalization is necessary to estimate the physical effects of the vacuum transition. Thus, in this paper, we revisit the electroweak vacuum instability from the perspective of quantum field theory (QFT) in curved space-time, and discuss the dynamical behavior of the homogeneous Higgs field phi determined by the effective potential V eff( phi ) in curved space-time and the renormalized vacuum fluctuations < δ phi 2 >ren via adiabatic regularization and point-splitting regularization. We simply suppose that the Higgs field only couples the gravity via the non-minimal Higgs-gravity coupling ξ(μ). In this scenario, the electroweak vacuum stability is inevitably threatened by the dynamical behavior of the homogeneous Higgs field phi, or the formations of AdS domains or bubbles unless the Hubble scale is small enough H< ΛI .

Advanced MRI in Blast-related TBI

DTIC Science & Technology

2012-07-01

test two advanced MRI methods, DTI and resting-state fMRI, in active-duty military blast-related TBI patients acutely after injury and correlate...Introduction: The purpose of the research effort was to test two advanced MRI methods, DTI and resting-state fMRI, in active-duty military blast-related TBI...clinical follow-up assessments and repeat scans on 78 subjects with TBI and 18 controls. 9) We extensively analyzed DTI , resting-state fMRI, and

Space shuttle holddown post blast shield

NASA Technical Reports Server (NTRS)

Larracas, F. B.

1991-01-01

The original and subsequent designs of the Solid Rocket Booster/Holddown Post blast shield assemblies and their associated hardware are described. It presents the major problems encountered during their early use in the Space Shuttle Program, during the Return-to-Flight Modification Phase, and during their fabrication and validation testing phases. The actions taken to correct the problems are discussed, along with the various concepts now being considered to increase the useful life of the blast shield.

Model for small arms fire muzzle blast wave propagation in air

NASA Astrophysics Data System (ADS)

Aguilar, Juan R.; Desai, Sachi V.

2011-11-01

Accurate modeling of small firearms muzzle blast wave propagation in the far field is critical to predict sound pressure levels, impulse durations and rise times, as functions of propagation distance. Such a task being relevant to a number of military applications including the determination of human response to blast noise, gunfire detection and localization, and gun suppressor design. Herein, a time domain model to predict small arms fire muzzle blast wave propagation is introduced. The model implements a Friedlander wave with finite rise time which diverges spherically from the gun muzzle. Additionally, the effects in blast wave form of thermoviscous and molecular relaxational processes, which are associated with atmospheric absorption of sound were also incorporated in the model. Atmospheric absorption of blast waves is implemented using a time domain recursive formula obtained from numerical integration of corresponding differential equations using a Crank-Nicholson finite difference scheme. Theoretical predictions from our model were compared to previously recorded real world data of muzzle blast wave signatures obtained by shooting a set different sniper weapons of varying calibers. Recordings containing gunfire acoustical signatures were taken at distances between 100 and 600 meters from the gun muzzle. Results shows that predicted blast wave slope and exponential decay agrees well with measured data. Analysis also reveals the persistency of an oscillatory phenomenon after blast overpressure in the recorded wave forms.

Dynamic Modelling of Fault Slip Induced by Stress Waves due to Stope Production Blasts

NASA Astrophysics Data System (ADS)

Sainoki, Atsushi; Mitri, Hani S.

2016-01-01

Seismic events can take place due to the interaction of stress waves induced by stope production blasts with faults located in close proximity to stopes. The occurrence of such seismic events needs to be controlled to ensure the safety of the mine operators and the underground mine workings. This paper presents the results of a dynamic numerical modelling study of fault slip induced by stress waves resulting from stope production blasts. First, the calibration of a numerical model having a single blast hole is performed using a charge weight scaling law to determine blast pressure and damping coefficient of the rockmass. Subsequently, a numerical model of a typical Canadian metal mine encompassing a fault parallel to a tabular ore deposit is constructed, and the simulation of stope extraction sequence is carried out with static analyses until the fault exhibits slip burst conditions. At that point, the dynamic analysis begins by applying the calibrated blast pressure to the stope wall in the form of velocities generated by the blast holes. It is shown from the results obtained from the dynamic analysis that the stress waves reflected on the fault create a drop of normal stresses acting on the fault, which produces a reduction in shear stresses while resulting in fault slip. The influence of blast sequences on the behaviour of the fault is also examined assuming several types of blast sequences. Comparison of the blast sequence simulation results indicates that performing simultaneous blasts symmetrically induces the same level of seismic events as separate blasts, although seismic energy is more rapidly released when blasts are performed symmetrically. On the other hand when nine blast holes are blasted simultaneously, a large seismic event is induced, compared to the other two blasts. It is concluded that the separate blasts might be employed under the adopted geological conditions. The developed methodology and procedure to arrive at an ideal blast sequence can

Effects of different blasting materials on charge generation and decay on titanium surface after sandblasting.

PubMed

Guo, Cecilia Yan; Hong Tang, Alexander Tin; Hon Tsoi, James Kit; Matinlinna, Jukka Pekka

2014-04-01

It has been reported that sandblasting titanium with alumina (Al2O3) powder could generate a negative electric charge on titanium surface. This has been proven to promote osteoblast activities and possibly osseointegration. The purpose of this pilot study was to investigate the effects of different blasting materials, in terms of the grit sizes and electro-negativity, on the generation of a negative charge on the titanium surface. The aim was also to make use of these results to deduct the underlying mechanism of charge generation by sandblasting. Together 60 c.p. 2 titanium plates were machine-cut and polished for sandblasting, and divided into 6 groups with 10 plates in each. Every plate in the study groups was sandblasted with one of the following 6 powder materials: 110µm Al2O3 grits, 50µm Al2O3 grits, 150-300µm glass beads, 45-75µm glass beads, 250µm Al powder and 44µm Al powder. The static voltage on the surface of every titanium plate was measured immediately after sandblasting. The static voltages of the titanium plates were recorded and processed using statistical analysis. The results suggested that only sandblasting with 45-75µm glass beads generated a positive charge on titanium, while using all other blasting materials lead to a negative charge. Furthermore, blasting grits of the same powder material but of different sizes might lead to different amount and polarity of the charges. This triboelectric effect is likely to be the main mechanism for charge generation through sandblasting. Copyright © 2014 Elsevier Ltd. All rights reserved.

Germanium detector vacuum encapsulation

NASA Technical Reports Server (NTRS)

Madden, N. W.; Malone, D. F.; Pehl, R. H.; Cork, C. P.; Luke, P. N.; Landis, D. A.; Pollard, M. J.

1991-01-01

This paper describes an encapsulation technology that should significantly improve the viability of germanium gamma-ray detectors for a number of important applications. A specialized vacuum chamber has been constructed in which the detector and the encapsulating module are processed in high vacuum. Very high vacuum conductance is achieved within the valveless encapsulating module. The detector module is then sealed without breaking the chamber vacuum. The details of the vacuum chamber, valveless module, processing, and sealing method are presented.

Detecting blast-induced infrasound in wind noise.

PubMed

Howard, Wheeler B; Dillion, Kevin L; Shields, F Douglas

2010-03-01

Current efforts seek to monitor and investigate such naturally occurring events as volcanic eruptions, hurricanes, bolides entering the atmosphere, earthquakes, and tsunamis by the infrasound they generate. Often, detection of the infrasound signal is limited by the masking effect of wind noise. This paper describes the use of a distributed array to detect infrasound signals from four atmospheric detonations at White Sands Missile Range in New Mexico, USA in 2006. Three of the blasts occurred during times of low wind noise and were easily observed with array processing techniques. One blast was obscured by high wind conditions. The results of signal processing are presented that allowed localization of the blast-induced signals in the presence of wind noise in the array response.

Characterization of viscoelastic materials for low-magnitude blast mitigation

NASA Astrophysics Data System (ADS)

Bartyczak, S.; Mock, W.

2014-05-01

Recent research indicates that exposure to low amplitude blast waves, such as IED detonation or multiple firings of a weapon, causes damage to brain tissue resulting in Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD). Current combat helmets are not sufficiently protecting warfighters from this danger and the effects are debilitating, costly, and long-lasting. The objective of the present work is to evaluate the blast mitigating behavior of current helmet materials and new materials designed for blast mitigation using a test fixture recently developed at the Naval Surface Warfare Center Dahlgren Division for use with an existing gas gun. The 40-mm-bore gas gun was used as a shock tube to generate blast waves (ranging from 0.5 to 2 bar) in the test fixture mounted on the gun muzzle. A fast opening valve was used to release helium gas from the breech which formed into a blast wave and impacted instrumented targets in the test fixture. Blast attenuation of selected materials was determined through the measurement of stress data in front of and behind the target. Materials evaluated in this research include polyurethane foam from currently fielded US Army and Marine Corps helmets, polyurea 1000, and three hardnesses of Sorbothane (48, 58, and 70 durometer, Shore 00). Polyurea 1000 and 6061-T6 aluminum were used to calibrate the stress gauges.

Blast Technologies

DTIC Science & Technology

2011-06-27

Development Generic Hull Testing Airbag and Sensor Technology Development Blast Data Recorder Specifications and Fielding Numerical Model Improvement...seat designs, airbag and restraint systems, and energy absorbing flooring solutions  Vehicle event data recorders for collecting highly accurate...treatments.  Airbag or comparable technologies such as bolsters.  Sensors that can detect and deploy/trigger interior treatments within the timeframe of a

Creation of smart composites using an embroidery machine

NASA Astrophysics Data System (ADS)

Torii, Nobuhiro; Oka, Kosuke; Ikeda, Tadashige

2016-04-01

A smart composite with functional fibers and reinforcement fibers optimally placed with an embroidery machine was created. Fiber orientation affects mechanical properties of composite laminates significantly. Accordingly, if the fibers can be placed along a desired curved path, fiber reinforced plastic (FRP) structures can be designed more lightly and more sophisticatedly. To this end a tailored fiber placement method using the embroidery machine have been studied. To add functions to the FRP structures, shape memory alloy (SMA) wires were placed as functional fibers. First, for a certain purpose the paths of the reinforcement fibers and the SMA wires were simultaneously optimized in analysis. Next, the reinforcement fibers and tubes with the SMA wires were placed on fabrics by using the embroidery machine and this fabric was impregnated with resin by using the vacuum assisted resin transfer molding method. This smart composite was activated by applying voltage to the SMA wires. Fundamental properties of the smart composite were examined and the feasibility of the proposed creation method was shown.

Lasting retinal injury in a mouse model of blast-induced trauma

USDA-ARS?s Scientific Manuscript database

Traumatic brain injury (TBI) due to blast exposure is currently the most prevalent of war injuries. While secondary ocular blast injuries due to flying debris are more common, primary ocular blast exposure has been reported among survivors of explosions, but with limited understanding of the resulti...

Development of High Interruption Capability Vacuum Circuit Breaker -Technology of Vacuum Arc Control-

NASA Astrophysics Data System (ADS)

Niwa, Yoshimitsu; Kaneko, Eiji

Vacuum circuit breakers (VCB) have been widely used for power distribution systems. Vacuum Interrupters, which are the current interruption unit, have been increased its interruption capability with the development of vacuum arc control technology by magnetic field. There are three major type electrodes: disk shaped electrodes, radial magnetic field electrodes, axial magnetic field (AMF) electrodes. In the disk shaped electrode, the vacuum arc between the electrodes is not controlled. In the AMF electrode, the vacuum arc is diffused and stabilized by an axial magnetic field, which is parallel to the arc current. In the last type of electrodes, the vacuum arc column is rotated by magnetic force generated by the current flowing in the electrodes. The interruption current and the voltage of one break VCB is increased to 100 kA, 144 kV respectively. This paper describes basic configurations and functions of VCB, vacuum arc control technology in vacuum interrupters, recent researches and applications of VCB.

Electroweak vacuum instability and renormalized Higgs field vacuum fluctuations in the inflationary universe

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kohri, Kazunori; Matsui, Hiroki, E-mail: kohri@post.kek.jp, E-mail: matshiro@post.kek.jp

In this work, we investigated the electroweak vacuum instability during or after inflation. In the inflationary Universe, i.e., de Sitter space, the vacuum field fluctuations < δ φ {sup 2} > enlarge in proportion to the Hubble scale H {sup 2}. Therefore, the large inflationary vacuum fluctuations of the Higgs field < δ φ {sup 2} > are potentially catastrophic to trigger the vacuum transition to the negative-energy Planck-scale vacuum state and cause an immediate collapse of the Universe. However, the vacuum field fluctuations < δ φ {sup 2} >, i.e., the vacuum expectation values have an ultraviolet divergence, andmore » therefore a renormalization is necessary to estimate the physical effects of the vacuum transition. Thus, in this paper, we revisit the electroweak vacuum instability from the perspective of quantum field theory (QFT) in curved space-time, and discuss the dynamical behavior of the homogeneous Higgs field φ determined by the effective potential V {sub eff}( φ ) in curved space-time and the renormalized vacuum fluctuations < δ φ {sup 2} >{sub ren} via adiabatic regularization and point-splitting regularization. We simply suppose that the Higgs field only couples the gravity via the non-minimal Higgs-gravity coupling ξ(μ). In this scenario, the electroweak vacuum stability is inevitably threatened by the dynamical behavior of the homogeneous Higgs field φ, or the formations of AdS domains or bubbles unless the Hubble scale is small enough H < Λ {sub I} .« less

Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information.

PubMed

Song, Jiangning; Burrage, Kevin; Yuan, Zheng; Huber, Thomas

2006-03-09

The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds adopt the cis form. Proline cis/trans isomerization is known to play a critical role in protein folding, splicing, cell signaling and transmembrane active transport. Accurate prediction of proline cis/trans isomerization in proteins would have many important applications towards the understanding of protein structure and function. In this paper, we propose a new approach to predict the proline cis/trans isomerization in proteins using support vector machine (SVM). The preliminary results indicated that using Radial Basis Function (RBF) kernels could lead to better prediction performance than that of polynomial and linear kernel functions. We used single sequence information of different local window sizes, amino acid compositions of different local sequences, multiple sequence alignment obtained from PSI-BLAST and the secondary structure information predicted by PSIPRED. We explored these different sequence encoding schemes in order to investigate their effects on the prediction performance. The training and testing of this approach was performed on a newly enlarged dataset of 2424 non-homologous proteins determined by X-Ray diffraction method using 5-fold cross-validation. Selecting the window size 11 provided the best performance for determining the proline cis/trans isomerization based on the single amino acid sequence. It was found that using multiple sequence alignments in the form of PSI-BLAST profiles could significantly improve the prediction performance, the prediction accuracy increased from 62.8% with single sequence to 69.8% and Matthews Correlation Coefficient (MCC) improved from 0.26 with single local sequence to 0.40. Furthermore, if coupled with the predicted secondary structure information by PSIPRED, our method yielded a prediction accuracy of 71.5% and MCC of 0.43, 9% and 0

The cleaning of ward floors and the bacteriological study of floor-cleaning machines

PubMed Central

Bate, J. G.

1961-01-01

Current trends in ward flooring materials and cleaning methods are considered from the point of view of the hospital bacteriologist. Methods employed in an investigation into the bacteriological safety of a number of floor-cleaning machines are described, and some considerations governing the choice of vacuum cleaners for ward use are discussed. Images PMID:13687726

Introduction to the magnet and vacuum systems of an electron storage ring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weng, W.T.

An accelerator or storage ring complex is a concerted interplay of various functional systems. For the convenience of discussion we can divide it into the following systems: injector, magnet, RF, vacuum, instrumentation and control. In addition, the conventional construction of the building and radiation safety consideration are also needed and finally the beam lines, detector, data acquisition and analysis set-ups for research programs. Dr. L. Teng has given a comprehensive review of the whole complex and the operation of such a facility. I concentrate on the description of magnet and vacuum systems. Only the general function of each system andmore » the basic design concepts will be introduced, no detailed engineering practice will be given which will be best done after a machine design is produced. For further understanding and references a table of bibliography is provided at the end of the paper.« less

Tympanic membrane perforation after combat blast exposure in Iraq: a poor biomarker of primary blast injury.

PubMed

Harrison, Corey D; Bebarta, Vikhyat S; Grant, Gerald A

2009-07-01

The US military has reported over 10,000 improvised explosive device attacks attributing to over 400 deaths in Iraq in 2005. Otologic blast injury and tympanic membrane (TM) perforation have traditionally been used as a predictor, or biomarker, of serious or occult primary blast injury (PBI). Although combat injuries from the US-Iraq conflict have been described, the utility of TM perforation as a marker of PBI has not. The objective of this study is to determine the incidence of tympanic perforation in patients subject to blast exposures and describe its utility as a biomarker of more serious primary barotrauma, as observed at a US military hospital in Iraq. In our institutional review board-approved study, all patients during a 30-day period who arrived at a tertiary US military hospital in Iraq were evaluated. All patients with blast injures were identified on arrival to the hospital emergency department and were followed up through their hospital course and evacuation to the United States to assure they received proper otolaryngology evaluation and follow-up. Demographic data and manifestations of PBI (TM perforation, pneumothorax, pulmonary contusion, nonpenetrating facial sinus injury, and bowel perforation) and other combat injuries were recorded. The diagnostic tests and clinical examination findings used to identify these complications were also recorded. One hundred sixty-seven patients were enrolled over 30 days. All blast exposures resulted from primary or secondary explosions from munitions used in combat. This included both combatants and civilians. All patients were men. The mean patient age was 28 years (range, 12-55 years). Sixteen percent (27 of 167) of blast-exposed patients had TM perforation. Thirteen of 27 patients with perforations had bilateral perforations. Twelve of 167 patients (7%) had PBI. Six of 12 patients (50%) with PBI had TM perforation. The use of TM perforation as a biomarker for PBI resulted in a sensitivity of 50% (95% CI, 22

Application of directional blasting in mining and civil engineering, 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chernigovskii, A.A.

1986-01-01

The author describes the mechanism of breaking mineral rocks through blasting and offers recommendations on the application of directional blasting in mining and civil engineering. He also introduces criteria for cost-effectiveness of transporting rock mass from stope to pile by means of energy of explosion. And, the book presents ballistic tables to be used in constructing the trajectory of movement of a rock fragment during blasting operations while taking into account the topography of the land. In this edition, the author presents a more detailed theoretical treatment on the mechanism of fragmentation of a monolithic or fissured rock mass throughmore » blasting.« less

Off-center blast in a shocked medium

NASA Astrophysics Data System (ADS)

Duncan-Miller, G. C.; Stone, W. D.

2018-07-01

When multiple blasts occur at different times, the situation arises in which a blast wave is propagating into a medium that has already been shocked. Determining the evolution in the shape of the second shock is not trivial, as it is propagating into air that is not only non-uniform, but also non-stationary. To accomplish this task, we employ the method of Kompaneets to determine the shape of a shock in a non-uniform media. We also draw from the work of Korycansky (Astrophys J 398:184-189. https://doi.org/10.1086/171847 , 1992) on an off-center explosion in a medium with radially varying density. Extending this to treat non-stationary flow, and making use of approximations to the Sedov solution for the point blast problem, we are able to determine an analytic expression for the evolving shape of the second shock. In particular, we consider the case of a shock in air at standard ambient temperature and pressure, with the second shock occurring shortly after the original blast wave reaches it, as in a sympathetic detonation.

blastjs: a BLAST+ wrapper for Node.js.

PubMed

Page, Martin; MacLean, Dan; Schudoma, Christian

2016-02-27

To cope with the ever-increasing amount of sequence data generated in the field of genomics, the demand for efficient and fast database searches that drive functional and structural annotation in both large- and small-scale genome projects is on the rise. The tools of the BLAST+ suite are the most widely employed bioinformatic method for these database searches. Recent trends in bioinformatics application development show an increasing number of JavaScript apps that are based on modern frameworks such as Node.js. Until now, there is no way of using database searches with the BLAST+ suite from a Node.js codebase. We developed blastjs, a Node.js library that wraps the search tools of the BLAST+ suite and thus allows to easily add significant functionality to any Node.js-based application. blastjs is a library that allows the incorporation of BLAST+ functionality into bioinformatics applications based on JavaScript and Node.js. The library was designed to be as user-friendly as possible and therefore requires only a minimal amount of code in the client application. The library is freely available under the MIT license at https://github.com/teammaclean/blastjs.

Relationship between orientation to a blast and pressure wave propagation inside the rat brain.

PubMed

Chavko, Mikulas; Watanabe, Tomas; Adeeb, Saleena; Lankasky, Jason; Ahlers, Stephen T; McCarron, Richard M

2011-01-30

Exposure to a blast wave generated during an explosion may result in brain damage and related neurological impairments. Several mechanisms by which the primary blast wave can damage the brain have been proposed, including: (1) a direct effect of the shock wave on the brain causing tissue damage by skull flexure and propagation of stress and shear forces; and (2) an indirect transfer of kinetic energy from the blast, through large blood vessels and cerebrospinal fluid (CSF), to the central nervous system. To address a basic question related to the mechanisms of blast brain injury, pressure was measured inside the brains of rats exposed to a low level of blast (~35kPa), while positioned in three different orientations with respect to the primary blast wave; head facing blast, right side exposed to blast and head facing away from blast. Data show different patterns and durations of the pressure traces inside the brain, depending on the rat orientation to blast. Frontal exposures (head facing blast) resulted in pressure traces of higher amplitude and longer duration, suggesting direct transmission and reflection of the pressure inside the brain (dynamic pressure transfer). The pattern of the pressure wave inside the brain in the head facing away from blast exposures assumes contribution of the static pressure, similar to hydrodynamic pressure to the pressure wave inside the brain. Published by Elsevier B.V.

30 CFR 817.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-UNDERGROUND MINING ACTIVITIES § 817.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 817.11. The operator shall...

30 CFR 817.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-UNDERGROUND MINING ACTIVITIES § 817.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 817.11. The operator shall...

30 CFR 817.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-UNDERGROUND MINING ACTIVITIES § 817.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 817.11. The operator shall...

30 CFR 817.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-UNDERGROUND MINING ACTIVITIES § 817.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 817.11. The operator shall...

30 CFR 817.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-UNDERGROUND MINING ACTIVITIES § 817.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 817.11. The operator shall...

40 CFR 63.1543 - Standards for process and process fugitive sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... section. (1) Sinter machine; (2) Blast furnace; (3) Dross furnace; (4) Dross furnace charging location; (5) Blast furnace and dross furnace tapping location; (6) Sinter machine charging location; (7) Sinter machine discharge end; (8) Sinter crushing and sizing equipment; and (9) Sinter machine area. (b) The...

Continuum modeling of neuronal cell under blast loading

PubMed Central

Jérusalem, Antoine; Dao, Ming

2012-01-01

Traumatic brain injuries have recently been put under the spotlight as one of the most important causes of accidental brain dysfunctions. Significant experimental and modeling efforts are thus ongoing to study the associated biological, mechanical and physical mechanisms. In the field of cell mechanics, progresses are also being made at the experimental and modeling levels to better characterize many of the cell functions such as differentiation, growth, migration and death, among others. The work presented here aims at bridging both efforts by proposing a continuum model of neuronal cell submitted to blast loading. In this approach, cytoplasm, nucleus and membrane (plus cortex) are differentiated in a representative cell geometry, and different material constitutive models are adequately chosen for each one. The material parameters are calibrated against published experimental work of cell nanoindentation at multiple rates. The final cell model is ultimately subjected to blast loading within a complete fluid-structure interaction computational framework. The results are compared to the nanoindentation simulation and the specific effects of the blast wave on the pressure and shear levels at the interfaces are identified. As a conclusion, the presented model successfully captures some of the intrinsic intracellular phenomena occurring during its deformation under blast loading and potentially leading to cell damage. It suggests more particularly the localization of damage at the nucleus membrane similarly to what has already been observed at the overall cell membrane. This degree of damage is additionally predicted to be worsened by a longer blast positive phase duration. As a conclusion, the proposed model ultimately provides a new three dimensional computational tool to evaluate intracellular damage during blast loading. PMID:22562014

30 CFR 816.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-SURFACE MINING ACTIVITIES § 816.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 816.11. The operator shall— (1...

30 CFR 816.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-SURFACE MINING ACTIVITIES § 816.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 816.11. The operator shall— (1...

30 CFR 816.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-SURFACE MINING ACTIVITIES § 816.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 816.11. The operator shall— (1...

30 CFR 816.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-SURFACE MINING ACTIVITIES § 816.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 816.11. The operator shall— (1...

30 CFR 816.66 - Use of explosives: Blasting signs, warnings, and access control.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Use of explosives: Blasting signs, warnings... STANDARDS-SURFACE MINING ACTIVITIES § 816.66 Use of explosives: Blasting signs, warnings, and access control. (a) Blasting signs. Blasting signs shall meet the specifications of § 816.11. The operator shall— (1...

Blast-Induced Color Change in Photonic Crystals Corresponds with Brain Pathology

PubMed Central

Cullen, D. Kacy; Browne, Kevin D.; Xu, Yongan; Adeeb, Saleena; Wolf, John A.; McCarron, Richard M.; Yang, Shu; Chavko, Mikulas

2011-01-01

Abstract A high incidence of blast exposure is a 21st century reality in counter-insurgency warfare. However, thresholds for closed-head blast-induced traumatic brain injury (bTBI) remain unknown. Moreover, without objective information about relative blast exposure, warfighters with bTBI may not receive appropriate medical care and may remain in harm's way. Accordingly, we have engineered a blast injury dosimeter (BID) using a photonic crystalline material that changes color following blast exposure. The photonic crystals are fabricated using SU-8 via multi-beam interference laser lithography. The final BID is similar in appearance to an array of small colored stickers that may be affixed to uniforms or helmets in multiple locations. Although durable under normal conditions, the photonic crystalline micro- and nano-structure are precisely altered by blast to create a color change. These BIDs were evaluated using a rat model of bTBI, for which blast shockwave exposure was generated via a compressed air-driven shock tube. With prototype BID arrays affixed to the animals, we found that BID color changes corresponded with subtle brain pathologies, including neuronal degeneration and reactive astrocytosis. These subtle changes were most notable in the dentate gyrus of the hippocampus, cerebral cortex, and cerebellum. These data demonstrate the feasibility of using a materials-based, power-free colorimetric BID as the first self-contained blast sensor calibrated to correspond with brain pathology. PMID:22082449

Use of computer systems and process information for blast furnace operations at U. S. Steel, Gary Works

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sherman, G.J.; Zmierski, M.L.

1994-09-01

US Steel Iron Producing Div. consists of four operating blast furnaces ranging in process control capabilities from 1950's and 1960's era hardware to state of the art technology. The oldest control system consists of a large number of panels containing numerous relays, indicating lights, selector switches, push buttons, analog controllers, strip chart recorders and annunciators. In contrast, the state of the art control system utilizes remote I/O, two sets of redundant PLC's, redundant charge director computer, redundant distributed control system, high resolution video-graphic display system and supervisory computer for real-time data acquisition. Process data are collected and archived on twomore » DEC VAX computers, one for No. 13 blast furnace and the other for the three south end furnaces. Historical trending, data analysis and reporting are available to iron producing personnel through terminals and PC's connected directly to the systems, dial-up modems and various network configurations. These two machines are part of the iron producing network which allows them to pass and receive information from each other as well as numerous other sources throughout the division. This configuration allows personnel to access most pertinent furnace information from a single source. The basic objective of the control systems is to charge raw materials to the top of the furnace at aim weights and sequence, while maintaining blast conditions at the bottom of the furnace at required temperature, pressure and composition. Control changes by the operators are primarily supervisory based on review of system generated plots and tables.« less

Progress Toward Optimizing Prosthetic Socket Fit and Suspension Using Elevated Vacuum to Promote Residual Limb Health

PubMed Central

Wernke, Matthew M.; Schroeder, Ryan M.; Haynes, Michael L.; Nolt, Lonnie L.; Albury, Alexander W.; Colvin, James M.

2017-01-01

Objective: Prosthetic sockets are custom made for each amputee, yet there are no quantitative tools to determine the appropriateness of socket fit. Ensuring a proper socket fit can have significant effects on the health of residual limb soft tissues and overall function and acceptance of the prosthetic limb. Previous work found that elevated vacuum pressure data can detect movement between the residual limb and the prosthetic socket; however, the correlation between the two was specific to each user. The overall objective of this work is to determine the relationship between elevated vacuum pressure deviations and prosthetic socket fit. Approach: A tension compression machine was used to apply repeated controlled forces onto a residual limb model with sockets of different internal volume. Results: The vacuum pressure–displacement relationship was dependent on socket fit. The vacuum pressure data were sensitive enough to detect differences of 1.5% global volume and can likely detect differences even smaller. Limb motion was reduced as surface area of contact between the limb model and socket was maximized. Innovation: The results suggest that elevated vacuum pressure data provide information to quantify socket fit. Conclusions: This study provides evidence that the use of elevated vacuum pressure data may provide a method for prosthetists to quantify and monitor socket fit. Future studies should investigate the relationship between socket fit, limb motion, and limb health to define optimal socket fit parameters. PMID:28736683

Single Pass Streaming BLAST on FPGAs*†

PubMed Central

Herbordt, Martin C.; Model, Josh; Sukhwani, Bharat; Gu, Yongfeng; VanCourt, Tom

2008-01-01

Approximate string matching is fundamental to bioinformatics and has been the subject of numerous FPGA acceleration studies. We address issues with respect to FPGA implementations of both BLAST- and dynamic-programming- (DP) based methods. Our primary contribution is a new algorithm for emulating the seeding and extension phases of BLAST. This operates in a single pass through a database at streaming rate, and with no preprocessing other than loading the query string. Moreover, it emulates parameters turned to maximum possible sensitivity with no slowdown. While current DP-based methods also operate at streaming rate, generating results can be cumbersome. We address this with a new structure for data extraction. We present results from several implementations showing order of magnitude acceleration over serial reference code. A simple extension assures compatibility with NCBI BLAST. PMID:19081828

Paint removal using wheat starch blast media

NASA Astrophysics Data System (ADS)

Foster, Terry; Oestreich, John

1993-03-01

A review of the Wheat Starch Blasting technology is presented. Laboratory evaluations covering Almen Arc testing on bare 2024-T3 aluminum and magnesium, as well as crack detection on 7075-T6 bare aluminum, are discussed. Comparisons with Type V plastic media show lower residual stresses are achieved on aluminum and magnesium with wheat starch media. Dry blasting effects on the detection of cracks confirms better crack visibility with wheat starch media versus Type V or Type II plastic media. Testing of wheat starch media in several composite test programs, including fiberglass, Kevlar, and graphite-epoxy composites, showed no fiber damage. Process developments and production experience at the first U.S. aircraft stripping facility are also reviewed. Corporate and regional aircraft are being stripped in this three nozzle dry blast hanger.

Viscoelastic Materials Study for the Mitigation of Blast-Related Brain Injury

NASA Astrophysics Data System (ADS)

Bartyczak, Susan; Mock, Willis, Jr.

2011-06-01

Recent preliminary research into the causes of blast-related brain injury indicates that exposure to blast pressures, such as from IED detonation or multiple firings of a weapon, causes damage to brain tissue resulting in Traumatic Brain Injury (TBI) and Post Traumatic Stress Disorder (PTSD). Current combat helmets are not sufficient to protect the warfighter from this danger and the effects are debilitating, costly, and long-lasting. Commercially available viscoelastic materials, designed to dampen vibration caused by shock waves, might be useful as helmet liners to dampen blast waves. The objective of this research is to develop an experimental technique to test these commercially available materials when subject to blast waves and evaluate their blast mitigating behavior. A 40-mm-bore gas gun is being used as a shock tube to generate blast waves (ranging from 1 to 500 psi) in a test fixture at the gun muzzle. A fast opening valve is used to release nitrogen gas from the breech to impact instrumented targets. The targets consist of aluminum/ viscoelastic polymer/ aluminum materials. Blast attenuation is determined through the measurement of pressure and accelerometer data in front of and behind the target. The experimental technique, calibration and checkout procedures, and results will be presented.

Surface assessment and modification of concrete using abrasive blasting

NASA Astrophysics Data System (ADS)

Millman, Lauren R.

Composite systems are applied to concrete substrates to strengthen and extend the service life. Successful restoration or rehabilitation requires surface preparation prior to the application of the overlay. Surface coatings, waterproofing systems, and other external surface applications also require surface preparation prior to application. Abrasive blast media is often used to clean and uniformly roughen the substrate. The appropriate surface roughness is necessary to facilitate a strong bond between the existing substrate and overlay. Thus, surface modification using abrasive blast media (sand and dry ice), their respective environmental effects, surface roughness characterization prior to and after blasting, and the adhesion between the substrate and overlay are the focus of this dissertation. This dissertation is comprised of an introduction, a literature review, and four chapters, the first of which addresses the environmental effects due to abrasive blasting using sand, water, and dry ice. The assessment considered four response variables: carbon dioxide (CO2) emissions, fuel and energy consumption, and project duration. The results indicated that for sand blasting and water jetting, the primary factor contributing to environmental detriment was CO22 emissions from vehicular traffic near the construction site. The second chapter is an analysis of the International Concrete Repair Institute's (ICRI) concrete surface profiles (CSPs) using 3-D optical profilometry. The primary objective was to evaluate the suitability of approximating the 3-D surface (areal) parameters with those extracted from 2-D (linear) profiles. Four profile directions were considered: two diagonals, and lines parallel and transverse to the longitudinal direction of the mold. For any CSP mold, the estimation of the 3-D surface roughness using a 2-D linear profile resulted in underestimation and overestimation errors exceeding 50%, demonstrating the inadequacy of 2-D linear profiles to

BLAST: The Balloon-Borne Large Aperture Submillimeter Telescope

NASA Technical Reports Server (NTRS)

Devlin, Mark; Ade, Peter; Bock, Jamie; Dicker, Simon; Griffin, Matt; Gunderson, Josh; Halpern, Mark; Hargrave, Peter; Hughes, David; Klein, Jeff

2004-01-01

BLAST is the Balloon-borne Large-Aperture Sub-millimeter Telescope. It will fly from a Long Duration Balloon (LDB) platform from Antarctica. The telescope design incorporates a 2 m primary mirror with large-format bolometer arrays operating at 250, 350 and 500 microns. By providing the first sensitive large-area (10 sq. deg.) sub-mm surveys at these wavelengths, BLAST will address some of the most important galactic and cosmological questions regarding the formation and evolution of stars, galaxies and clusters. Galactic and extragalactic BLAST surveys will: (1) identify large numbers of high-redshift galaxies; (2) measure photometric redshifts, rest-frame FIR luminosities and star formation rates thereby constraining the evolutionary history of the galaxies that produce the FIR and sub-mm background; (3) measure cold pre-stellar sources associated with the earliest stages of star and planet formation; (4) make high-resolution maps of diffuse galactic emission over a wide range of galactic latitudes. In addition to achieving the above scientific goals, the exciting legacy of the BLAST LDB experiment will be a catalogue of 3000-5000 extragalactic sub-mm sources and a 100 sq. deg. sub-mm galactic plane survey. Multi-frequency follow-up observations from SIRTF, ASTRO-F, and Herschel, together with spectroscopic observations and sub-arcsecond imaging from ALMA are essential to understand the physical nature of the BLAST sources.

PaperBLAST: Text Mining Papers for Information about Homologs

PubMed Central

Arkin, Adam P.

2017-01-01

ABSTRACT Large-scale genome sequencing has identified millions of protein-coding genes whose function is unknown. Many of these proteins are similar to characterized proteins from other organisms, but much of this information is missing from annotation databases and is hidden in the scientific literature. To make this information accessible, PaperBLAST uses EuropePMC to search the full text of scientific articles for references to genes. PaperBLAST also takes advantage of curated resources (Swiss-Prot, GeneRIF, and EcoCyc) that link protein sequences to scientific articles. PaperBLAST’s database includes over 700,000 scientific articles that mention over 400,000 different proteins. Given a protein of interest, PaperBLAST quickly finds similar proteins that are discussed in the literature and presents snippets of text from relevant articles or from the curators. PaperBLAST is available at http://papers.genomics.lbl.gov/. IMPORTANCE With the recent explosion of genome sequencing data, there are now millions of uncharacterized proteins. If a scientist becomes interested in one of these proteins, it can be very difficult to find information as to its likely function. Often a protein whose sequence is similar, and which is likely to have a similar function, has been studied already, but this information is not available in any database. To help find articles about similar proteins, PaperBLAST searches the full text of scientific articles for protein identifiers or gene identifiers, and it links these articles to protein sequences. Then, given a protein of interest, it can quickly find similar proteins in its database by using standard software (BLAST), and it can show snippets of text from relevant papers. We hope that PaperBLAST will make it easier for biologists to predict proteins’ functions. PMID:28845458

Minimization of Blast furnace Fuel Rate by Optimizing Burden and Gas Distribution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dr. Chenn Zhou

2012-08-15

The goal of the research is to improve the competitive edge of steel mills by using the advanced CFD technology to optimize the gas and burden distributions inside a blast furnace for achieving the best gas utilization. A state-of-the-art 3-D CFD model has been developed for simulating the gas distribution inside a blast furnace at given burden conditions, burden distribution and blast parameters. The comprehensive 3-D CFD model has been validated by plant measurement data from an actual blast furnace. Validation of the sub-models is also achieved. The user friendly software package named Blast Furnace Shaft Simulator (BFSS) has beenmore » developed to simulate the blast furnace shaft process. The research has significant benefits to the steel industry with high productivity, low energy consumption, and improved environment.« less

Analysis of Abrasive Blasting of DOP-26 Iridium Alloy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohriner, Evan Keith; Zhang, Wei; Ulrich, George B

2012-01-01

The effects of abrasive blasting on the surface geometry and microstructure of DOP-26 iridium alloy (Ir-0.3% W-0.006% Th 0.005% Al) have been investigated. Abrasive blasting has been used to control emissivity of components operating at elevated temperature. The effects of abrasive blasting conditions on surface morphology were investigated both experimentally and by numerical modeling. The simplified model, based on finite element analysis of a single angular particle impacting on Ir alloy disk, calculates the surface deformation and residual strain distribution. The experimental results and modeling results both indicate that the surface geometry is not sensitive to the abrasive blast processmore » conditions of nozzle pressure and standoff distance considered in this study. On the other hand, the modeling results suggest that the angularity of the abrasive particle has an important role in determining surface geometry, which in turn, affects the emissivity. Abrasive blasting causes localized surface strains and localized recrystallization, but it does not affect grain size following extended exposure at elevated temperature. The dependence of emissivity of the DOP-26 alloy on mean surface slope follows a similar trend to that reported for pure iridium.« less

Gun muzzle blast and flash

NASA Astrophysics Data System (ADS)

Klingenberg, Guenter; Heimerl, Joseph M.

A repository of fundamental experimental and analytical data concerning the complex phenomena associated with gun-muzzle blast and flash effects is presented, proceeding from gun muzzle signatures to modern gun-propulsion concepts, interior and transitional ballistics, and characterizations of blast-wave research and muzzle flash. Data are presented in support of a novel hypothesis which explains the ignition of secondary flash and elucidates the means for its suppression. Both chemical and mechanical (often competing) methods of flash suppression are treated. The historical work of Kesslau and Ladenburg is noted, together with French, British, Japanese and American research efforts and current techniques of experimental characterization for gun muzzle phenomena.

Ground vibration monitoring for construction blasting in urban areas

DOT National Transportation Integrated Search

2001-04-01

The primary objectives of this study were to determine a recommendation for the pre-blast area for surveys, and to obtain actual field vibrations from rock blasting operations, in populated regions within specific geologic units. The area confined wi...

Relationship of goat milk flow emission variables with milking routine, milking parameters, milking machine characteristics and goat physiology.

PubMed

Romero, G; Panzalis, R; Ruegg, P

2017-11-01

The aim of this paper was to study the relationship between milk flow emission variables recorded during milking of dairy goats with variables related to milking routine, goat physiology, milking parameters and milking machine characteristics, to determine the variables affecting milking performance and help the goat industry pinpoint farm and milking practices that improve milking performance. In total, 19 farms were visited once during the evening milking. Milking parameters (vacuum level (VL), pulsation ratio and pulsation rate, vacuum drop), milk emission flow variables (milking time, milk yield, maximum milk flow (MMF), average milk flow (AVMF), time until 500 g/min milk flow is established (TS500)), doe characteristics of 8 to 10 goats/farm (breed, days in milk and parity), milking practices (overmilking, overstripping, pre-lag time) and milking machine characteristics (line height, presence of claw) were recorded on every farm. The relationships between recorded variables and farm were analysed by a one-way ANOVA analysis. The relationships of milk yield, MMF, milking time and TS500 with goat physiology, milking routine, milking parameters and milking machine design were analysed using a linear mixed model, considering the farm as the random effect. Farm was significant (P<0.05) in all the studied variables. Milk emission flow variables were similar to those recommended in scientific studies. Milking parameters were adequate in most of the farms, being similar to those recommended in scientific studies. Few milking parameters and milking machine characteristics affected the tested variables: average vacuum level only showed tendency on MMF, and milk pipeline height on TS500. Milk yield (MY) was mainly affected by parity, as the interaction of days in milk with parity was also significant. Milking time was mainly affected by milk yield and breed. Also significant were parity, the interaction of days in milk with parity and overstripping, whereas overmilking

30 CFR 57.22605 - Blasting from the surface (V-A mines).

Code of Federal Regulations, 2013 CFR

2013-07-01

... Standards for Methane in Metal and Nonmetal Mines Explosives § 57.22605 Blasting from the surface (V-A mines). (a) All development and production blasting shall be initiated from the surface after all persons are... methane in the mine is less than 1.0 percent, persons may enter the mine, and all places blasted shall be...

30 CFR 57.22605 - Blasting from the surface (V-A mines).

Code of Federal Regulations, 2014 CFR

2014-07-01

... Standards for Methane in Metal and Nonmetal Mines Explosives § 57.22605 Blasting from the surface (V-A mines). (a) All development and production blasting shall be initiated from the surface after all persons are... methane in the mine is less than 1.0 percent, persons may enter the mine, and all places blasted shall be...

30 CFR 57.22605 - Blasting from the surface (V-A mines).

Code of Federal Regulations, 2012 CFR

2012-07-01

... Standards for Methane in Metal and Nonmetal Mines Explosives § 57.22605 Blasting from the surface (V-A mines). (a) All development and production blasting shall be initiated from the surface after all persons are... methane in the mine is less than 1.0 percent, persons may enter the mine, and all places blasted shall be...

30 CFR 57.22605 - Blasting from the surface (V-A mines).

Code of Federal Regulations, 2010 CFR

2010-07-01

... Standards for Methane in Metal and Nonmetal Mines Explosives § 57.22605 Blasting from the surface (V-A mines). (a) All development and production blasting shall be initiated from the surface after all persons are... methane in the mine is less than 1.0 percent, persons may enter the mine, and all places blasted shall be...

30 CFR 57.22605 - Blasting from the surface (V-A mines).

Code of Federal Regulations, 2011 CFR

2011-07-01

... Standards for Methane in Metal and Nonmetal Mines Explosives § 57.22605 Blasting from the surface (V-A mines). (a) All development and production blasting shall be initiated from the surface after all persons are... methane in the mine is less than 1.0 percent, persons may enter the mine, and all places blasted shall be...

A Homogenization Approach for Design and Simulation of Blast Resistant Composites

NASA Astrophysics Data System (ADS)

Sheyka, Michael

Structural composites have been used in aerospace and structural engineering due to their high strength to weight ratio. Composite laminates have been successfully and extensively used in blast mitigation. This dissertation examines the use of the homogenization approach to design and simulate blast resistant composites. Three case studies are performed to examine the usefulness of different methods that may be used in designing and optimizing composite plates for blast resistance. The first case study utilizes a single degree of freedom system to simulate the blast and a reliability based approach. The first case study examines homogeneous plates and the optimal stacking sequence and plate thicknesses are determined. The second and third case studies use the homogenization method to calculate the properties of composite unit cell made of two different materials. The methods are integrated with dynamic simulation environments and advanced optimization algorithms. The second case study is 2-D and uses an implicit blast simulation, while the third case study is 3-D and simulates blast using the explicit blast method. Both case studies 2 and 3 rely on multi-objective genetic algorithms for the optimization process. Pareto optimal solutions are determined in case studies 2 and 3. Case study 3 is an integrative method for determining optimal stacking sequence, microstructure and plate thicknesses. The validity of the different methods such as homogenization, reliability, explicit blast modeling and multi-objective genetic algorithms are discussed. Possible extension of the methods to include strain rate effects and parallel computation is also examined.

Post-blasting seismicity in Rudna copper mine, Poland - source parameters analysis.

NASA Astrophysics Data System (ADS)

Caputa, Alicja; Rudziński, Łukasz; Talaga, Adam

2017-04-01

The really important hazard in Polish copper mines is high seismicity and corresponding rockbursts. Many methods are used to reduce the seismic hazard. Among others the most effective is preventing blasting in potentially hazardous mining panels. The method is expected to provoke small moderate tremors (up to M2.0) and reduce in this way a stress accumulation in the rockmass. This work presents an analysis, which deals with post-blasting events in Rudna copper mine, Poland. Using the Full Moment Tensor (MT) inversion and seismic spectra analysis, we try to find some characteristic features of post blasting seismic sources. Source parameters estimated for post-blasting events are compared with the parameters of not-provoked mining events that occurred in the vicinity of the provoked sources. Our studies show that focal mechanisms of events which occurred after blasts have similar MT decompositions, namely are characterized by a quite strong isotropic component as compared with the isotropic component of not-provoked events. Also source parameters obtained from spectral analysis show that provoked seismicity has a specific source physics. Among others, it is visible from S to P wave energy ratio, which is higher for not-provoked events. The comparison of all our results reveals a three possible groups of sources: a) occurred just after blasts, b) occurred from 5min to 24h after blasts and c) not-provoked seismicity (more than 24h after blasting). Acknowledgements: This work was supported within statutory activities No3841/E-41/S/2016 of Ministry of Science and Higher Education of Poland.

Microstructural consequences of blast lung injury characterised with digital volume correlation

NASA Astrophysics Data System (ADS)

Arora, Hari; Nila, Alex; Vitharana, Kalpani; Sherwood, Joseph M.; Nguyen, Thuy-Tien N.; Karunaratne, Angelo; Mohammed, Idris K.; Bodey, Andrew J.; Hellyer, Peter J.; Overby, Darryl R.; Schroter, Robert C.; Hollis, Dave

2017-12-01

This study focuses on microstructural changes that occur within the mammalian lung when subject to blast and how these changes influence strain distributions within the tissue. Shock tube experiments were performed to generate the blast injured specimens (cadaveric Sprague-Dawley rats). Blast overpressures of 100 kPa and 180 kPa were studied. Synchrotron tomography imaging was used to capture volumetric image data of lungs. Specimens were ventilated using a custom-built system to study multiple inflation pressures during each tomography scan. This data enabled the first digital volume correlation (DVC) measurements in lung tissue to be performed. Quantitative analysis was performed to describe the damaged architecture of the lung. No clear changes in the microstructure of the tissue morphology were observed due to controlled low to moderate level blast exposure. However, significant focal sites of injury were observed using DVC, which allowed detection of bias and concentration in the patterns of strain level. Morphological analysis corroborated the findings, illustrating that the focal damage caused by a blast can give rise to diffuse influence across the tissue. It is important to characterise the non-instantly fatal doses of blast, given the transient nature of blast lung in the clinical setting. This research has highlighted the need for better understanding of focal injury and its zone of influence (alveolar inter-dependency and neighbouring tissue burden as a result of focal injury). Digital volume correlation techniques show great promise as a tool to advance this endeavour, providing a new perspective on lung mechanics post-blast.

Assessing Neuro-Systemic & Behavioral Components in the Pathophysiology of Blast-Related Brain Injury

PubMed Central

Kobeissy, Firas; Mondello, Stefania; Tümer, Nihal; Toklu, Hale Z.; Whidden, Melissa A.; Kirichenko, Nataliya; Zhang, Zhiqun; Prima, Victor; Yassin, Walid; Anagli, John; Chandra, Namas; Svetlov, Stan; Wang, Kevin K. W.

2013-01-01

Among the U.S. military personnel, blast injury is among the leading causes of brain injury. During the past decade, it has become apparent that even blast injury as a form of mild traumatic brain injury (mTBI) may lead to multiple different adverse outcomes, such as neuropsychiatric symptoms and long-term cognitive disability. Blast injury is characterized by blast overpressure, blast duration, and blast impulse. While the blast injuries of a victim close to the explosion will be severe, majority of victims are usually at a distance leading to milder form described as mild blast TBI (mbTBI). A major feature of mbTBI is its complex manifestation occurring in concert at different organ levels involving systemic, cerebral, neuronal, and neuropsychiatric responses; some of which are shared with other forms of brain trauma such as acute brain injury and other neuropsychiatric disorders such as post-traumatic stress disorder. The pathophysiology of blast injury exposure involves complex cascades of chronic psychological stress, autonomic dysfunction, and neuro/systemic inflammation. These factors render blast injury as an arduous challenge in terms of diagnosis and treatment as well as identification of sensitive and specific biomarkers distinguishing mTBI from other non-TBI pathologies and from neuropsychiatric disorders with similar symptoms. This is due to the “distinct” but shared and partially identified biochemical pathways and neuro-histopathological changes that might be linked to behavioral deficits observed. Taken together, this article aims to provide an overview of the current status of the cellular and pathological mechanisms involved in blast overpressure injury and argues for the urgent need to identify potential biomarkers that can hint at the different mechanisms involved. PMID:24312074

Assessing neuro-systemic & behavioral components in the pathophysiology of blast-related brain injury.

PubMed

Kobeissy, Firas; Mondello, Stefania; Tümer, Nihal; Toklu, Hale Z; Whidden, Melissa A; Kirichenko, Nataliya; Zhang, Zhiqun; Prima, Victor; Yassin, Walid; Anagli, John; Chandra, Namas; Svetlov, Stan; Wang, Kevin K W

2013-11-21

Among the U.S. military personnel, blast injury is among the leading causes of brain injury. During the past decade, it has become apparent that even blast injury as a form of mild traumatic brain injury (mTBI) may lead to multiple different adverse outcomes, such as neuropsychiatric symptoms and long-term cognitive disability. Blast injury is characterized by blast overpressure, blast duration, and blast impulse. While the blast injuries of a victim close to the explosion will be severe, majority of victims are usually at a distance leading to milder form described as mild blast TBI (mbTBI). A major feature of mbTBI is its complex manifestation occurring in concert at different organ levels involving systemic, cerebral, neuronal, and neuropsychiatric responses; some of which are shared with other forms of brain trauma such as acute brain injury and other neuropsychiatric disorders such as post-traumatic stress disorder. The pathophysiology of blast injury exposure involves complex cascades of chronic psychological stress, autonomic dysfunction, and neuro/systemic inflammation. These factors render blast injury as an arduous challenge in terms of diagnosis and treatment as well as identification of sensitive and specific biomarkers distinguishing mTBI from other non-TBI pathologies and from neuropsychiatric disorders with similar symptoms. This is due to the "distinct" but shared and partially identified biochemical pathways and neuro-histopathological changes that might be linked to behavioral deficits observed. Taken together, this article aims to provide an overview of the current status of the cellular and pathological mechanisms involved in blast overpressure injury and argues for the urgent need to identify potential biomarkers that can hint at the different mechanisms involved.

Study of consumer fireworks post-blast residues by ATR-FTIR.

PubMed

Martín-Alberca, Carlos; Zapata, Félix; Carrascosa, Héctor; Ortega-Ojeda, Fernando E; García-Ruiz, Carmen

2016-03-01

Specific analytical procedures are requested for the forensic analysis of pre- and post-blast consumer firework samples, which present significant challenges. Up to date, vibrational spectroscopic techniques such as Fourier transform infrared spectroscopy (FTIR) have not been tested for the analysis of post-blast residues in spite of their interesting strengths for the forensic field. Therefore, this work proposes a simple and fast procedure for the sampling and analysis of consumer firework post-blast residues by a portable FTIR instrument with an Attenuated Total Reflection (ATR) accessory. In addition, the post-blast residues spectra of several consumer fireworks were studied in order to achieve the identification of their original chemical compositions. Hence, this work analysed 22 standard reagents usually employed to make consumer fireworks, or because they are related to their combustion products. Then, 5 different consumer fireworks were exploded, and their residues were sampled with dry cotton swabs and directly analysed by ATR-FTIR. In addition, their pre-blast fuses and charges were also analysed in order to stablish a proper comparison. As a result, the identification of the original chemical compositions of the post-blast samples was obtained. Some of the compounds found were potassium chlorate, barium nitrate, potassium nitrate, potassium perchlorate or charcoal. An additional study involving chemometric tools found that the results might greatly depend on the swab head type used for the sampling, and its sampling efficiency. The proposed procedure could be used as a complementary technique for the analysis of consumer fireworks post-blast residues. Copyright © 2015 Elsevier B.V. All rights reserved.

Vacuum-sintered body of a novel apatite for artificial bone

NASA Astrophysics Data System (ADS)

Tamura, Kenichi; Fujita, Tatsushi; Morisaki, Yuriko

2013-12-01

We produced regenerative artificial bone material and bone parts using vacuum-sintered bodies of a novel apatite called "Titanium medical apatite (TMA®)" for biomedical applications. TMA was formed by chemically connecting a Ti oxide molecule with the reactive [Ca10(PO4)6] group of Hydroxyapatite (HAp). The TMA powders were kneaded with distilled water, and solid cylinders of compacted TMA were made by compression molding at 10 MPa using a stainless-steel vessel. The TMA compacts were dried and then sintered in vacuum (about 10-3 Pa) or in air using a resistance heating furnace in the temperature range 1073-1773 K. TMA compacts were sintered at temperatures greater than 1073 K, thus resulting in recrystallization. The TMA compact bodies sintered in the range 1273-1773 K were converted into mixtures composed of three crystalline materials: α-TCP (tricalcium phosphate), β-TCP, and Perovskite-CaTiO3. The Perovskite crystals were stable and hard. In vacuum-sintering, the Perovskite crystals were transformed into fibers (approximately 1 µm in diameter × 8 µm in length), and the fiber distribution was uniform in various directions. We refer to the TMA vacuum-sintered bodies as a "reinforced composite material with Perovskite crystal fibers." However, in atmospheric sintering, the Perovskite crystals were of various sizes and were irregularly distributed as a result of the effect of oxygen. After sintering temperature at 1573 K, the following results were obtained: the obtained TMA vacuum-sintered bodies (1) were white, (2) had a density of approximately 2300 kg/m3 (corresponding to that of a compact bone or a tooth), and had a thermal conductivity of approximately 31.3 W/(m·K) (corresponding to those of metal or ceramic implants). Further, it was possible to cut the TMA bodies into various forms with a cutting machine. An implant made of TMA and inserted into a rabbit jaw bone was covered by new bone tissues after just one month because of the high

High Vacuum Creep Facility in the Materials Processing Laboratory

NASA Image and Video Library

1973-01-21

Technicians at work in the Materials Processing Laboratory’s Creep Facility at the National Aeronautics and Space Administration (NASA) Lewis Research Center. The technicians supported the engineers’ studies of refractory materials, metals, and advanced superalloys. The Materials Processing Laboratory contained laboratories and test areas equipped to prepare and develop these metals and materials. The ultra-high vacuum lab, seen in this photograph, contained creep and tensile test equipment. Creep testing is used to study a material’s ability to withstand long durations under constant pressure and temperatures. The equipment measured the strain over a long period of time. Tensile test equipment subjects the test material to strain until the material fails. The two tests were used to determine the strength and durability of different materials. The Materials Processing Laboratory also housed arc and electron beam melting furnaces, a hydraulic vertical extrusion press, compaction and forging equipment, and rolling mills and swagers. There were cryogenic and gas storage facilities and mechanical and oil diffusion vacuum pumps. The facility contained both instrumental and analytical chemistry laboratories for work on radioactive or toxic materials and the only shop to machine toxic materials in the Midwest.

Radiation hard vacuum switch

DOEpatents

Boettcher, Gordon E.

1990-01-01

A vacuum switch with an isolated trigger probe which is not directly connected to the switching electrodes. The vacuum switch within the plasmatron is triggered by plasma expansion initiated by the trigger probe which travels through an opening to reach the vacuum switch elements. The plasma arc created is directed by the opening to the space between the anode and cathode of the vacuum switch to cause conduction.

Radiation hard vacuum switch

DOEpatents

Boettcher, Gordon E.

1990-03-06

A vacuum switch with an isolated trigger probe which is not directly connected to the switching electrodes. The vacuum switch within the plasmatron is triggered by plasma expansion initiated by the trigger probe which travels through an opening to reach the vacuum switch elements. The plasma arc created is directed by the opening to the space between the anode and cathode of the vacuum switch to cause conduction.

Cloth ballistic vest alters response to blast.

PubMed

Phillips, Y Y; Mundie, T G; Yelverton, J T; Richmond, D R

1988-01-01

Ballistic wounds have been and will remain the principal cause of casualties in combat. Cloth ballistic vests (CBV) play an important role in limiting critical wounds from fragments and small-arms fire. There is an increased risk of primary blast injury on the modern battlefield. In a previous study, volunteers were exposed to short-duration blast waves of low peak pressure (18.6 +/- 0.8 kPa). Pressure measurements made in the distal esophagus as an estimate of intrathoracic pressure (ITP) were significantly higher (p less than 0.05) when the standard U.S. Army ballistic jacket was worn (8.7 +/- 1.2 kPa) than when fatigues alone were worn (7.4 +/- 0.7 kPa). In this study 58 sheep were exposed to nominal blast levels of 115, 230, 295, and 420 kPa peak pressure in groups of 12, 18, 16, and 12, respectively. Half of each group was fitted with a CBV. Lung weight index (LWI), lung weight expressed as a percentage of body weight, was used as a measure of blast injury. Use of the CBV was associated with a significant increase in LWI (p less than 0.05) which averaged 21% for the two middle exposure groups. At the 420 kPa level, two of six non-CBV animals died as opposed to five of six animals wearing the CBV. Intrathoracic pressure was generally higher in the CBV group. Likely mechanisms of injury enhancement include an increase in target surface area and an alteration of the effective loading function on the thorax. This information may be useful in the triage and treatment of casualties exposed to intense blast environments.

Blast shock wave mitigation using the hydraulic energy redirection and release technology.

PubMed

Chen, Yun; Huang, Wei; Constantini, Shlomi

2012-01-01

A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder) if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel.

Blast Shock Wave Mitigation Using the Hydraulic Energy Redirection and Release Technology

PubMed Central

Chen, Yun; Huang, Wei; Constantini, Shlomi

2012-01-01

A hydraulic energy redirection and release technology has been developed for mitigating the effects of blast shock waves on protected objects. The technology employs a liquid-filled plastic tubing as a blast overpressure transformer to transfer kinetic energy of blast shock waves into hydraulic energy in the plastic tubings. The hydraulic energy is redirected through the plastic tubings to the openings at the lower ends, and then is quickly released with the liquid flowing out through the openings. The samples of the specifically designed body armor in which the liquid-filled plastic tubings were installed vertically as the outer layer of the body armor were tested. The blast test results demonstrated that blast overpressure behind the body armor samples was remarkably reduced by 97% in 0.2 msec after the liquid flowed out of its appropriate volume through the openings. The results also suggested that a volumetric liquid surge might be created when kinetic energy of blast shock wave was transferred into hydraulic energy to cause a rapid physical movement or displacement of the liquid. The volumetric liquid surge has a strong destructive power, and can cause a noncontact, remote injury in humans (such as blast-induced traumatic brain injury and post-traumatic stress disorder) if it is created in cardiovascular system. The hydraulic energy redirection and release technology can successfully mitigate blast shock waves from the outer surface of the body armor. It should be further explored as an innovative approach to effectively protect against blast threats to civilian and military personnel. PMID:22745740

Internal ballistics of the detonation products of a blast-hole charge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mangush, S.K.; Garbunov, V.A.

1986-07-01

The authors investigate the gasdynamic flow of the detonation products of a blast-hole charge (the expansion of the detonation products in the blast hole and the gas outflow and propagation of shock airwaves into the face space). The problem is solved by means of a numerical program for integration of partial differential equations of one-dimensional gas-dynamics. A numerical model of the internal ballistics of a blast-hole charge is presented. In addition to the variation of the thermodynamic parameters in the blast hole, the formation of the shock wave in the face space is shown, which is the source of gasmore » ignition. Further development of the numerical model of the action of blast-hole charges is planned which will involve an analysis of a number of applied problems.« less

Dynamic strain distribution of FRP plate under blast loading

NASA Astrophysics Data System (ADS)

Saburi, T.; Yoshida, M.; Kubota, S.

2017-02-01

The dynamic strain distribution of a fiber re-enforced plastic (FRP) plate under blast loading was investigated using a Digital Image Correlation (DIC) image analysis method. The testing FRP plates were mounted in parallel to each other on a steel frame. 50 g of composition C4 explosive was used as a blast loading source and set in the center of the FRP plates. The dynamic behavior of the FRP plate under blast loading were observed by two high-speed video cameras. The set of two high-speed video image sequences were used to analyze the FRP three-dimensional strain distribution by means of DIC method. A point strain profile extracted from the analyzed strain distribution data was compared with a directly observed strain profile using a strain gauge and it was shown that the strain profile under the blast loading by DIC method is quantitatively accurate.

Prediction of blast-induced air overpressure: a hybrid AI-based predictive model.

PubMed

Jahed Armaghani, Danial; Hajihassani, Mohsen; Marto, Aminaton; Shirani Faradonbeh, Roohollah; Mohamad, Edy Tonnizam

2015-11-01

Blast operations in the vicinity of residential areas usually produce significant environmental problems which may cause severe damage to the nearby areas. Blast-induced air overpressure (AOp) is one of the most important environmental impacts of blast operations which needs to be predicted to minimize the potential risk of damage. This paper presents an artificial neural network (ANN) optimized by the imperialist competitive algorithm (ICA) for the prediction of AOp induced by quarry blasting. For this purpose, 95 blasting operations were precisely monitored in a granite quarry site in Malaysia and AOp values were recorded in each operation. Furthermore, the most influential parameters on AOp, including the maximum charge per delay and the distance between the blast-face and monitoring point, were measured and used to train the ICA-ANN model. Based on the generalized predictor equation and considering the measured data from the granite quarry site, a new empirical equation was developed to predict AOp. For comparison purposes, conventional ANN models were developed and compared with the ICA-ANN results. The results demonstrated that the proposed ICA-ANN model is able to predict blast-induced AOp more accurately than other presented techniques.

Neck blast disease influences grain yield and quality traits of aromatic rice.

PubMed

Khan, Mohammad Ashik Iqbal; Bhuiyan, Md Rejwan; Hossain, Md Shahadat; Sen, Partha Pratim; Ara, Anjuman; Siddique, Md Abubakar; Ali, Md Ansar

2014-11-01

A critical investigation was conducted to find out the effect of neck blast disease on yield-contributing characters, and seed quality traits of aromatic rice in Bangladesh. Both healthy and neck-blast-infected panicles of three aromatic rice cultivars (high-yielding and local) were collected and investigated at Plant Pathology Division, Bangladesh Rice Research Institute (BRRI), Gazipur, Bangladesh. All of the tested varieties were highly susceptible to neck blast disease under natural conditions, though no leaf blast symptoms appear on leaves. Neck blast disease increased grain sterility percentages, reduced grain size, yield and quality traits of seeds. The degrees of yield and seed quality reduction depended on disease severity and variety's genetic make-up. Unfilled grains were the main source of seed-borne pathogen, especially for blast in the seed lot. Transmission of blast pathogen from neck (panicle base) to seed was very poor. These findings are important, especially concerning the seed certification programme in which seed lots are certified on the basis of field inspection. Finally, controlled experiments are needed to draw more critical conclusions. Copyright © 2014 Académie des sciences. Published by Elsevier SAS. All rights reserved.

An Empirical Model for Mine-Blast Loading

DTIC Science & Technology

2014-10-17

fledged experimental program. The numerical approach however suffers from several drawbacks in the mine blast simulations. First, it is a very...Suffield consisted in a pendulum type device to measure global impulse of buried mine [15]. One of the main purposes of the ONAGER pendulum was to study...TP-1 Terminal effects, KTA 1-34 report, 2004. [15] Bues, R., Hlady, S.L. and Bergeron, D.M., Pendulum Measurement of Land Mine Blast Output, Volume

Localized coating removal using plastic media blasting

NASA Technical Reports Server (NTRS)

Novak, Howard L.; Wyckoff, Michael G.; Zook, Lee M.

1988-01-01

Steps taken to qualify the use of plastic media blasting for safely and effectively removing paint and other coatings from solid rocket booster aluminum structures are described. As a result of the effort, an improvement was made in the design of surface finishing equipment for processing flight hardware, in addition to a potentially patentable idea on improved plastic media composition. The general arrangement of the blast equipment and the nozzle configuration are presented.

Blasting vibrations control: The shortcomings of traditional methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vuillaume, P.M.; Kiszlo, M.; Bernard, T.

1996-12-31

In the context of its studies for the French ministry of the environment and for the French national coal board, INERIS (the French institute for the industrial environment and hazards, formerly CERCHAR) has made a complete critical survey of the methods generally used to reduce the levels of blasting vibrations. It is generally acknowledged that the main parameter to control vibrations is the so-called instantaneous charge, or charge per delay. This should be reduced as much as possible in order to diminish vibration levels. On account of this, the use of a new generation of blasting devices, such as non-electricmore » detonators or electronic sequential timers has been developed since the seventies. INERIS has collected data from about 900 blasts in 2 quarries and 3 open pit mines. These data include input parameters such as borehole diameter, burden, spacing, charge per hole, charge per delay, total fired charge, etc ... They also include output measurements, such as vibration peak particle velocities, and main frequencies. These data have been analyzed with the help of multi variable statistical tools. Blasting tests were undertaken to evaluate new methods of vibrations control, such as the superposition of vibration signals. These methods appear to be accurate in many critical cases, but certainly would be highly improved with a better accuracy of firing delays. The development of electronic detonators seems to be the way of the future for a better blasting control.« less

Analysis of MINIE2013 Explosion Air-Blast Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schnurr, Julie M.; Rodgers, Arthur J.; Kim, Keehoon

We report analysis of air-blast overpressure measurements from the MINIE2013 explosive experiments. The MINIE2013 experiment involved a series of nearly 70 near-surface (height-ofburst, HOB, ranging from -1 to +4 m) low-yield (W=2-20 kg TNT equivalent) chemical highexplosives tests that were recorded at local distances (230 m – 28.5 km). Many of the W and HOB combinations were repeated, allowing for quantification of the variability in air-blast features and corresponding yield estimates. We measured canonical signal features (peak overpressure, impulse per unit area, and positive pulse duration) from the air-blast data and compared these to existing air-blast models. Peak overpressure measurementsmore » showed good agreement with the models at close ranges but tended to attenuate more rapidly at longer range (~ 1 km), which is likely caused by upward refraction of acoustic waves due to a negative vertical gradient of sound speed. We estimated yields of the MINIE2013 explosions using the Integrated Yield Determination Tool (IYDT). Errors of the estimated yields were on average within 30% of the reported yields, and there were no significant differences in the accuracy of the IYDT predictions grouped by yield. IYDT estimates tend to be lower than ground truth yields, possibly because of reduced overpressure amplitudes by upward refraction. Finally, we report preliminary results on a development of a new parameterized air-blast waveform.« less

Current advances on genetic resistance to rice blast disease

USDA-ARS?s Scientific Manuscript database

Rice blast disease caused by the fungal pathogen Magnaporthe oryzae is one of the most threatening fungal diseases resulting in significant annual crop losses worldwide. Blast disease has been effectively managed by a combination of resistant (R) gene deployment, application of fungicides, and suita...

Vacuum fluctuations in an ancestor vacuum: A possible dark energy candidate

NASA Astrophysics Data System (ADS)

Aoki, Hajime; Iso, Satoshi; Lee, Da-Shin; Sekino, Yasuhiro; Yeh, Chen-Pin

2018-02-01

We consider an open universe created by bubble nucleation, and study possible effects of our "ancestor vacuum," a de Sitter space in which bubble nucleation occurred, on the present universe. We compute vacuum expectation values of the energy-momentum tensor for a minimally coupled scalar field, carefully taking into account the effect of the ancestor vacuum by the Euclidean prescription. We pay particular attention to the so-called supercurvature mode, a non-normalizable mode on a spatial slice of the open universe, which has been known to exist for sufficiently light fields. This mode decays in time most slowly, and may leave residual effects of the ancestor vacuum, potentially observable in the present universe. We point out that the vacuum energy of the quantum field can be regarded as dark energy if mass of the field is of order the present Hubble parameter or smaller. We obtain preliminary results for the dark energy equation of state w (z ) as a function of the redshift.

Evaluation of copper slag blast media for railcar maintenance

NASA Technical Reports Server (NTRS)

Sagers, N. W.; Finlayson, Mack H.

1989-01-01

Copper slag was tested as a blasting substitute for zirconium silicate which is used to remove paint from railroad cars. The copper slag tested is less costly, strips paint faster, is produced near the point of need, provides a good bonding surface for paint, and permits the operator to work in a more comfortable position, i.e., standing nearly erect instead of having to crouch. Outdoor blasting with the tested Blackhawk (20 to 40 mesh) copper slag is also environmentally acceptable to the State of Utah. Results of tests for the surface erosion rate with copper slag blasting are included.

Simulation of blast-induced, early-time intracranial wave physics leading to traumatic brain injury.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, Paul Allen; Ford, Corey C.

U.S. soldiers are surviving blast and impacts due to effective body armor, trauma evacuation and care. Blast injuries are the leading cause of traumatic brain injury (TBI) in military personnel returning from combat. Understanding of Primary Blast Injury may be needed to develop better means of blast mitigation strategies. The objective of this paper is to investigate the effects of blast direction and strength on the resulting mechanical stress and wave energy distributions generated in the brain.

Primary Blast-Induced Traumatic Brain Injury in Rats Leads to Increased Prion Protein in Plasma: A Potential Biomarker for Blast-Induced Traumatic Brain Injury

PubMed Central

Pham, Nam; Sawyer, Thomas W.; Wang, Yushan; Jazii, Ferdous Rastgar; Vair, Cory

2015-01-01

Abstract Traumatic brain injury (TBI) is deemed the “signature injury” of recent military conflicts in Afghanistan and Iraq, largely because of increased blast exposure. Injuries to the brain can often be misdiagnosed, leading to further complications in the future. Therefore, the use of protein biomarkers for the screening and diagnosis of TBI is urgently needed. In the present study, we have investigated the plasma levels of soluble cellular prion protein (PrPC) as a novel biomarker for the diagnosis of primary blast-induced TBI (bTBI). We hypothesize that the primary blast wave can disrupt the brain and dislodge extracellular localized PrPC, leading to a rise in concentration within the systemic circulation. Adult male Sprague–Dawley rats were exposed to single pulse shockwave overpressures of varying intensities (15-30 psi or 103.4–206.8 kPa] using an advanced blast simulator. Blood plasma was collected 24 h after insult, and PrPC concentration was determined with a modified commercial enzyme-linked immunosorbent assay (ELISA) specific for PrPC. We provide the first report that mean PrPC concentration in primary blast exposed rats (3.97 ng/mL±0.13 SE) is significantly increased compared with controls (2.46 ng/mL±0.14 SE; two tailed test p<0.0001). Furthermore, we report a mild positive rank correlation between PrPC concentration and increasing blast intensity (psi) reflecting a plateaued response at higher pressure magnitudes, which may have implications for all military service members exposed to blast events. In conclusion, it appears that plasma levels of PrPC may be a novel biomarker for the detection of primary bTBI. PMID:25058115

Blast Design of Reinforced Concrete and Masonry Components Retrofitted with FRP

DTIC Science & Technology

2010-07-01

1 BLAST DESIGN OF REINFORCED CONCRETE AND MASONRY COMPONENTS RETROFITTED WITH FRP Marlon L. Bazan, Ph.D. and Charles J. Oswald, P.E., Ph.D...as an alternative to traditional methods for strengthening and retrofitting concrete and masonry structures to resist blast loads. The development...and experimental validation of a methodology for modeling the response of blast loaded concrete and masonry structural components retrofitted with FRP

Temporal Progression of Visual Injury from Blast Exposure

DTIC Science & Technology

2017-09-01

seen throughout the duration of the study. To correlate experimental blast exposures in rodents to human blast exposures, a computational parametric...software (JMP 10.0, Cary,NC). Descriptive and univariate analyses will first be performed to identify the occurrence of delayed visual system...later). The biostatistician evaluating the retrospective data has completed the descriptive analysis and is working on the multiple regression. Table

Blast TBI Models, Neuropathology, and Implications for Seizure Risk

PubMed Central

Kovacs, S. Krisztian; Leonessa, Fabio; Ling, Geoffrey S. F.

2014-01-01

Traumatic brain injury (TBI) due to explosive blast exposure is a leading combat casualty. It is also implicated as a key contributor to war related mental health diseases. A clinically important consequence of all types of TBI is a high risk for development of seizures and epilepsy. Seizures have been reported in patients who have suffered blast injuries in the Global War on Terror but the exact prevalence is unknown. The occurrence of seizures supports the contention that explosive blast leads to both cellular and structural brain pathology. Unfortunately, the exact mechanism by which explosions cause brain injury is unclear, which complicates development of meaningful therapies and mitigation strategies. To help improve understanding, detailed neuropathological analysis is needed. For this, histopathological techniques are extremely valuable and indispensable. In the following we will review the pathological results, including those from immunohistochemical and special staining approaches, from recent preclinical explosive blast studies. PMID:24782820

Vacuum Virtues

ERIC Educational Resources Information Center

Rathey, Allen

2007-01-01

Upright vacuums, like cars, vary in quality, features and performance. Like automobiles, some uprights are reliable, others may be problematic, and some become a problem as a result of neglect or improper use. So, how do education institutions make an informed choice and, having done so, ensure that an upright vacuum goes the distance? In this…

An RES-Based Model for Risk Assessment and Prediction of Backbreak in Bench Blasting

NASA Astrophysics Data System (ADS)

Faramarzi, F.; Ebrahimi Farsangi, M. A.; Mansouri, H.

2013-07-01

Most blasting operations are associated with various forms of energy loss, emerging as environmental side effects of rock blasting, such as flyrock, vibration, airblast, and backbreak. Backbreak is an adverse phenomenon in rock blasting operations, which imposes risk and increases operation expenses because of safety reduction due to the instability of walls, poor fragmentation, and uneven burden in subsequent blasts. In this paper, based on the basic concepts of a rock engineering systems (RES) approach, a new model for the prediction of backbreak and the risk associated with a blast is presented. The newly suggested model involves 16 effective parameters on backbreak due to blasting, while retaining simplicity as well. The data for 30 blasts, carried out at Sungun copper mine, western Iran, were used to predict backbreak and the level of risk corresponding to each blast by the RES-based model. The results obtained were compared with the backbreak measured for each blast, which showed that the level of risk achieved is in consistence with the backbreak measured. The maximum level of risk [vulnerability index (VI) = 60] was associated with blast No. 2, for which the corresponding average backbreak was the highest achieved (9.25 m). Also, for blasts with levels of risk under 40, the minimum average backbreaks (<4 m) were observed. Furthermore, to evaluate the model performance for backbreak prediction, the coefficient of correlation ( R 2) and root mean square error (RMSE) of the model were calculated ( R 2 = 0.8; RMSE = 1.07), indicating the good performance of the model.

Pathophysiology of blast-induced ocular trauma in rats after repeated exposure to low-level blast overpressure.

PubMed

Choi, Jae Hyek; Greene, Whitney A; Johnson, Anthony J; Chavko, Mikulas; Cleland, Jeffery M; McCarron, Richard M; Wang, Heuy-Ching

2015-04-01

The incidence of blast-induced ocular injury has dramatically increased due to advances in weaponry and military tactics. A single exposure to blast overpressure (BOP) has been shown to cause damage to the eye in animal models; however, on the battlefield, military personnel are exposed to BOP multiple times. The effects of repeated exposures to BOP on ocular tissues have not been investigated. The purpose of this study is to characterize the effects of single or repeated exposure on ocular tissues. A compressed air shock tube was used to deliver 70 ± 7 KPa BOP to rats, once (single blast overpressure [SBOP]) or once daily for 5 days (repeated blast overpressure [RBOP]). Immunohistochemistry was performed to characterize the pathophysiology of ocular injuries induced by SBOP and RBOP. Apoptosis was determined by quantification activated caspase 3. Gliosis was examined by detection of glial fibrillary acidic protein (GFAP). Inflammation was examined by detection of CD68. Activated caspase 3 was detected in ocular tissues from all animals subjected to BOP, while those exposed to RBOP had more activated caspase 3 in the optic nerve than those exposed to SBOP. GFAP was detected in the retinas from all animals subjected to BOP. CD68 was detected in optic nerves from all animals exposed to BOP. SBOP and RBOP induced retinal damage. RBOP caused more apoptosis in the optic nerve than SBOP, suggesting that RBOP causes more severe optic neuropathy than SBOP. SBOP and RBOP caused gliosis in the retina and increased inflammation in the optic nerve. © 2014 Royal Australian and New Zealand College of Ophthalmologists.

Mechanical and histological characterization of trachea tissue subjected to blast-type pressures

NASA Astrophysics Data System (ADS)

Butler, B. J.; Bo, C.; Tucker, A. W.; Jardine, A. P.; Proud, W. G.; Williams, A.; Brown, K. A.

2014-05-01

Injuries to the respiratory system can be a component of polytrauma in blast-loading injuries. Tissues located at air-liquid interfaces, including such tissues in the respiratory system, are particularly vulnerable to damage by blast overpressures. There is a lack of information about the mechanical and cellular responses that contribute to the damage of this class of tissues subjected to the high strain rates associated with blast loading. Here, we describe the results of dynamic blast-like pressure loading tests at high strain rates on freshly harvested ex vivo trachea tissue specimens.

Rapid condition assessment of structural condition after a blast using state-space identification

NASA Astrophysics Data System (ADS)

Eskew, Edward; Jang, Shinae

2015-04-01

After a blast event, it is important to quickly quantify the structural damage for emergency operations. In order improve the speed, accuracy, and efficiency of condition assessments after a blast, the authors have previously performed work to develop a methodology for rapid assessment of the structural condition of a building after a blast. The method involved determining a post-event equivalent stiffness matrix using vibration measurements and a finite element (FE) model. A structural model was built for the damaged structure based on the equivalent stiffness, and inter-story drifts from the blast are determined using numerical simulations, with forces determined from the blast parameters. The inter-story drifts are then compared to blast design conditions to assess the structures damage. This method still involved engineering judgment in terms of determining significant frequencies, which can lead to error, especially with noisy measurements. In an effort to improve accuracy and automate the process, this paper will look into a similar method of rapid condition assessment using subspace state-space identification. The accuracy of the method will be tested using a benchmark structural model, as well as experimental testing. The blast damage assessments will be validated using pressure-impulse (P-I) diagrams, which present the condition limits across blast parameters. Comparisons between P-I diagrams generated using the true system parameters and equivalent parameters will show the accuracy of the rapid condition based blast assessments.

Effects of Low-Level Blast Exposure on the Nervous System: Is There Really a Controversy?

PubMed Central

Elder, Gregory A.; Stone, James R.; Ahlers, Stephen T.

2014-01-01

High-pressure blast waves can cause extensive CNS injury in human beings. However, in combat settings, such as Iraq and Afghanistan, lower level exposures associated with mild traumatic brain injury (mTBI) or subclinical exposure have been much more common. Yet controversy exists concerning what traits can be attributed to low-level blast, in large part due to the difficulty of distinguishing blast-related mTBI from post-traumatic stress disorder (PTSD). We describe how TBI is defined in human beings and the problems posed in using current definitions to recognize blast-related mTBI. We next consider the problem of applying definitions of human mTBI to animal models, in particular that TBI severity in human beings is defined in relation to alteration of consciousness at the time of injury, which typically cannot be assessed in animals. However, based on outcome assessments, a condition of “low-level” blast exposure can be defined in animals that likely approximates human mTBI or subclinical exposure. We review blast injury modeling in animals noting that inconsistencies in experimental approach have contributed to uncertainty over the effects of low-level blast. Yet, animal studies show that low-level blast pressure waves are transmitted to the brain. In brain, low-level blast exposures cause behavioral, biochemical, pathological, and physiological effects on the nervous system including the induction of PTSD-related behavioral traits in the absence of a psychological stressor. We review the relationship of blast exposure to chronic neurodegenerative diseases noting the paradoxical lowering of Abeta by blast, which along with other observations suggest that blast-related TBI is pathophysiologically distinct from non-blast TBI. Human neuroimaging studies show that blast-related mTBI is associated with a variety of chronic effects that are unlikely to be explained by co-morbid PTSD. We conclude that abundant evidence supports low-level blast as having long

Sensory coding and cognitive processing of sound in Veterans with blast exposure

PubMed Central

Bressler, Scott; Goldberg, Hannah; Shinn-Cunningham, Barbara

2017-01-01

Recent anecdotal reports from VA audiology clinics as well as a few published studies have identified a sub-population of Service Members seeking treatment for problems communicating in everyday, noisy listening environments despite having normal to near-normal hearing thresholds. Because of their increased risk of exposure to dangerous levels of prolonged noise and transient explosive blast events, communication problems in these soldiers could be due to either hearing loss (traditional or “hidden”) in the auditory sensory periphery or from blast-induced injury to cortical networks associated with attention. We found that out of the 14 blast-exposed Service Members recruited for this study, 12 had hearing thresholds in the normal to near-normal range. A majority of these participants reported having problems specifically related to failures with selective attention. Envelope following responses (EFRs) measuring neural coding fidelity of the auditory brainstem to suprathreshold sounds were similar between blast-exposed and non-blast controls. Blast-exposed subjects performed substantially worse than non-blast controls in an auditory selective attention task in which listeners classified the melodic contour (rising, falling, or “zig-zagging”) of one of three simultaneous, competing tone sequences. Salient pitch and spatial differences made for easy segregation of the three concurrent melodies. Poor performance in the blast-exposed subjects was associated with weaker evoked response potentials (ERPs) in frontal EEG channels, as well as a failure of attention to enhance the neural responses evoked by a sequence when it was the target compared to when it was a distractor. These results suggest that communication problems in these listeners cannot be explained by compromised sensory representations in the auditory periphery, but rather point to lingering blast-induced damage to cortical networks implicated in the control of attention. Because all study

Compaction of Confining Materials in Pillar Blast Tests

NASA Astrophysics Data System (ADS)

Petropoulos, N.; Wimmer, M.; Johansson, D.; Nordlund, E.

2018-06-01

Two confined pillar tests were conducted at the Kiirunavaara mine to investigate the degree of compaction of three materials, i.e., 0-32-mm backfilled material, a blend of ore and waste material and caved material. Two blastholes were drilled parallel to each pillar wall, and several measurement holes were drilled in between the blastholes through each pillar. Both the measurement holes and backfilled materials, except the caved material, were instrumented. Two types of measurements were taken: dynamic measurements with accelerometers, and static measurements which considered the location of the instrumentation pre- and post-blast. Dynamic measurements involved the burden movement and the confining material behavior, and static measurements contained the final location of sensors inside and the angle of repose of the confining material. The results showed that the size distribution of the confining material affects its behavior under dynamic loading. The backfilled materials showed an apparent cohesion forming an agglomeration on the surface of the blasted burden. The burden moved as one slab due to simultaneous detonation. A gap was formed between the blasted burden and the new face. This gap was partially filled with burden erosion material which was finer fragmented than the blasted burden material.

Blast wave mitigation by dry aqueous foams

NASA Astrophysics Data System (ADS)

Del Prete, E.; Chinnayya, A.; Domergue, L.; Hadjadj, A.; Haas, J.-F.

2013-02-01

This paper presents results of experiments and numerical modeling on the mitigation of blast waves using dry aqueous foams. The multiphase formalism is used to model the dry aqueous foam as a dense non-equilibrium two-phase medium as well as its interaction with the high explosion detonation products. New experiments have been performed to study the mass scaling effects. The experimental as well as the numerical results, which are in good agreement, show that more than an order of magnitude reduction in the peak overpressure ratio can be achieved. The positive impulse reduction is less marked than the overpressures. The Hopkinson scaling is also found to hold particularly at larger scales for these two blast parameters. Furthermore, momentum and heat transfers, which have the main dominant role in the mitigation process, are shown to modify significantly the classical blast wave profile and thereafter to disperse the energy from the peak overpressure due to the induced relaxation zone. In addition, the velocity of the fireball, which acts as a piston on its environment, is smaller than in air. Moreover, the greater inertia of the liquid phase tends to project the aqueous foam far from the fireball. The created gap tempers the amplitude of the transmitted shock wave to the aqueous foam. As a consequence, this results in a lowering of blast wave parameters of the two-phase spherical decaying shock wave.

Blast vibration damage to water supply well - water quality and quantity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matheson, G.M.; Miller, D.K.

1997-05-01

Possible impacts to the water quality and production capacity of ground water supply wells by blasting is a common cause of complaints for blasting contractors, mining companies, and local regulatory authorities. The major complaints of changes in well water quality include; turbidity; discolored water (red, brown, black, yellow and milky water), and nitrate and/or coliform contamination. The major complaints for changes in well water production capacity include: loss of quantity production, air in water and/or water lines, damage to pump, and damage to well screen or borehole. The review of research and common causes of these problems indicates that mostmore » of these complaints are not related to blasting and can be shown to be related to either environmental factors, poor well construction, or wells whose elements required repair or replacement prior to blasting. The paper reviews each of the complaints cited and provides the probable causes of the observed condition and discusses their relation to blasting.« less

Microfabricated triggered vacuum switch

DOEpatents

Roesler, Alexander W [Tijeras, NM; Schare, Joshua M [Albuquerque, NM; Bunch, Kyle [Albuquerque, NM

2010-05-11

A microfabricated vacuum switch is disclosed which includes a substrate upon which an anode, cathode and trigger electrode are located. A cover is sealed over the substrate under vacuum to complete the vacuum switch. In some embodiments of the present invention, a metal cover can be used in place of the trigger electrode on the substrate. Materials used for the vacuum switch are compatible with high vacuum, relatively high temperature processing. These materials include molybdenum, niobium, copper, tungsten, aluminum and alloys thereof for the anode and cathode. Carbon in the form of graphitic carbon, a diamond-like material, or carbon nanotubes can be used in the trigger electrode. Channels can be optionally formed in the substrate to mitigate against surface breakdown.

Novel Approach to Conducting Blast Load Analyses Using Abaqus/Explicit-CEL

DTIC Science & Technology

2010-05-01

versus uncased, effects of afterburning , angle of incidence with respect to incoming shock, nearby geometry/barriers interacting with the shock...2. Blast parameters as a function of scaled distance – from TNT air blast data (DOE/TIC-11268, 1981). Due to inertial effects, the volume of air...positive phase duration) can be determined for a particular scaled distance. Figure 2 was generated from TNT air blast data for bare, spherical charges

Integration of Tuyere, Raceway and Shaft Models for Predicting Blast Furnace Process

NASA Astrophysics Data System (ADS)

Fu, Dong; Tang, Guangwu; Zhao, Yongfu; D'Alessio, John; Zhou, Chenn Q.

2018-06-01

A novel modeling strategy is presented for simulating the blast furnace iron making process. Such physical and chemical phenomena are taking place across a wide range of length and time scales, and three models are developed to simulate different regions of the blast furnace, i.e., the tuyere model, the raceway model and the shaft model. This paper focuses on the integration of the three models to predict the entire blast furnace process. Mapping output and input between models and an iterative scheme are developed to establish communications between models. The effects of tuyere operation and burden distribution on blast furnace fuel efficiency are investigated numerically. The integration of different models provides a way to realistically simulate the blast furnace by improving the modeling resolution on local phenomena and minimizing the model assumptions.

Influence of Gap Distance on Vacuum Arc Characteristics of Cup Type AMF Electrode in Vacuum Interrupters

NASA Astrophysics Data System (ADS)

Cheng, Shaoyong; Xiu, Shixin; Wang, Jimei; Shen, Zhengchao

2006-11-01

The greenhouse effect of SF6 is a great concern today. The development of high voltage vacuum circuit breakers becomes more important. The vacuum circuit breaker has minimum pollution to the environment. The vacuum interrupter is the key part of a vacuum circuit breaker. The interrupting characteristics in vacuum and arc-controlling technique are the main problems to be solved for a longer gap distance in developing high voltage vacuum interrupters. To understand the vacuum arc characteristics and provide effective technique to control vacuum arc in a long gap distance, the arc mode transition of a cup-type axial magnetic field electrode is observed by a high-speed charge coupled device (CCD) video camera under different gap distances while the arc voltage and arc current are recorded. The controlling ability of the axial magnetic field on vacuum arc obviously decreases when the gap distance is longer than 40 mm. The noise components and mean value of the arc voltage significantly increase. The effective method for controlling the vacuum arc characteristics is provided by long gap distances based on the test results. The test results can be used as a reference to develop high voltage and large capacity vacuum interrupters.

Large scale germplasm screening for identification of novel rice blast resistance sources

PubMed Central

Vasudevan, Kumar; Vera Cruz, Casiana M.; Gruissem, Wilhelm; Bhullar, Navreet K.

2014-01-01

Rice is a major cereal crop that contributes significantly to global food security. Biotic stresses, including the rice blast fungus, cause severe yield losses that significantly impair rice production worldwide. The rapid genetic evolution of the fungus often overcomes the resistance conferred by major genes after a few years of intensive agricultural use. Therefore, resistance breeding requires continuous efforts of enriching the reservoir of resistance genes/alleles to effectively tackle the disease. Seed banks represent a rich stock of genetic diversity, however, they are still under-explored for identifying novel genes and/or their functional alleles. We conducted a large-scale screen for new rice blast resistance sources in 4246 geographically diverse rice accessions originating from 13 major rice-growing countries. The accessions were selected from a total collection of over 120,000 accessions based on their annotated rice blast resistance information in the International Rice Genebank. A two-step resistance screening protocol was used involving natural infection in a rice uniform blast nursery and subsequent artificial infections with five single rice blast isolates. The nursery-resistant accessions showed varied disease responses when infected with single isolates, suggesting the presence of diverse resistance genes/alleles in this accession collection. In addition, 289 accessions showed broad-spectrum resistance against all five single rice blast isolates. The selected resistant accessions were genotyped for the presence of the Pi2 resistance gene, thereby identifying potential accessions for isolation of allelic variants of this blast resistance gene. Together, the accession collection with broad spectrum and isolate specific blast resistance represent the core material for isolation of previously unknown blast resistance genes and/or their allelic variants that can be deployed in rice breeding programs. PMID:25324853

Acceleration-based methodology to assess the blast mitigation performance of explosive ordnance disposal helmets

NASA Astrophysics Data System (ADS)

Dionne, J. P.; Levine, J.; Makris, A.

2018-01-01

To design the next generation of blast mitigation helmets that offer increasing levels of protection against explosive devices, manufacturers must be able to rely on appropriate test methodologies and human surrogates that will differentiate the performance level of various helmet solutions and ensure user safety. Ideally, such test methodologies and associated injury thresholds should be based on widely accepted injury criteria relevant within the context of blast. Unfortunately, even though significant research has taken place over the last decade in the area of blast neurotrauma, there currently exists no agreement in terms of injury mechanisms for blast-induced traumatic brain injury. In absence of such widely accepted test methods and injury criteria, the current study presents a specific blast test methodology focusing on explosive ordnance disposal protective equipment, involving the readily available Hybrid III mannequin, initially developed for the automotive industry. The unlikely applicability of the associated brain injury criteria (based on both linear and rotational head acceleration) is discussed in the context of blast. Test results encompassing a large number of blast configurations and personal protective equipment are presented, emphasizing the possibility to develop useful correlations between blast parameters, such as the scaled distance, and mannequin engineering measurements (head acceleration). Suggestions are put forward for a practical standardized blast testing methodology taking into account limitations in the applicability of acceleration-based injury criteria as well as the inherent variability in blast testing results.

Mathematical model of blasting schemes management in mining operations in presence of random disturbances

NASA Astrophysics Data System (ADS)

Kazakova, E. I.; Medvedev, A. N.; Kolomytseva, A. O.; Demina, M. I.

2017-11-01

The paper presents a mathematical model of blasting schemes management in presence of random disturbances. Based on the lemmas and theorems proved, a control functional is formulated, which is stable. A universal classification of blasting schemes is developed. The main classification attributes are suggested: the orientation in plan the charging wells rows relatively the block of rocks; the presence of cuts in the blasting schemes; the separation of the wells series onto elements; the sequence of the blasting. The periodic regularity of transition from one Short-delayed scheme of blasting to another is proved.

7. LOOKING EAST AT HOIST HOUSE No. 1 AND BLAST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. LOOKING EAST AT HOIST HOUSE No. 1 AND BLAST FURNACE No. 1, WITH ORE YARD AND ORE BRIDGES IN FOREGROUND. (Jet Lowe) - U.S. Steel Duquesne Works, Blast Furnace Plant, Along Monongahela River, Duquesne, Allegheny County, PA

Atmospheric particulate emissions from dry abrasive blasting using coal slag.

PubMed

Kura, Bhaskar; Kambham, Kalpalatha; Sangameswaran, Sivaramakrishnan; Potana, Sandhya

2006-08-01

Coal slag is one of the widely used abrasives in dry abrasive blasting. Atmospheric emissions from this process include particulate matter (PM) and heavy metals, such as chromium, lead, manganese, nickel. Quantities and characteristics of PM emissions depend on abrasive characteristics and process parameters. Emission factors are key inputs to estimate emissions. Experiments were conducted to study the effect of blast pressure, abrasive feed rate, and initial surface contamination on total PM (TPM) emission factors for coal slag. Rusted and painted mild steel surfaces were used as base plates. Blasting was carried out in an enclosed chamber, and PM was collected from an exhaust duct using U.S. Environment Protection Agency source sampling methods for stationary sources. Results showed that there is significant effect of blast pressure, feed rate, and surface contamination on TPM emissions. Mathematical equations were developed to estimate emission factors in terms of mass of emissions per unit mass of abrasive used, as well as mass of emissions per unit of surface area cleaned. These equations will help industries in estimating PM emissions based on blast pressure and abrasive feed rate. In addition, emissions can be reduced by choosing optimum operating conditions.

Controlled Blasting for Deconstruction of a Railway Bridge Near Sahibganj

NASA Astrophysics Data System (ADS)

Mandal, S. K.; Ghosh, A. K.; Oraon, S.

2018-06-01

Some of the Indian Railway bridges require reconstruction for electrification and expansion of railway tracks. Dismantling of bridge within time schedule in densely populated area requires controlled and pre-planned blasting methodology for safe pulling down of the structure and quick removal of blasted debris for fast restoration of tracks and smooth plying of trains. The three arched railway bridge (Bridge No. 61) located between Sahibganj and Karamtola cases one such example where the bridge was dismantled and the track was restored within 4 h of blasting, though the stipulated block period for demolition and restoration of tracks was 6 h. The 25.48 m long three-arched bridge was drilled and blasted with 225 number of blastholes (32 mm diameter) and 100 kg explosive (25 mm diameter). Length of blastholes varied between 0.5 and 1.8 m with blast geometry of 0.3-0.35 m burden and 0.33 m spacing. This paper deals with the conceptual and theoretical model developed for identification of the key locations for drilling and implementation of the same. It also discusses about the precautionary measures and the drilling pattern adopted for quick demolition and speedy restoration of tracks.

Controlled Blasting for Deconstruction of a Railway Bridge Near Sahibganj

NASA Astrophysics Data System (ADS)

Mandal, S. K.; Ghosh, A. K.; Oraon, S.

2018-02-01

Some of the Indian Railway bridges require reconstruction for electrification and expansion of railway tracks. Dismantling of bridge within time schedule in densely populated area requires controlled and pre-planned blasting methodology for safe pulling down of the structure and quick removal of blasted debris for fast restoration of tracks and smooth plying of trains. The three arched railway bridge (Bridge No. 61) located between Sahibganj and Karamtola cases one such example where the bridge was dismantled and the track was restored within 4 h of blasting, though the stipulated block period for demolition and restoration of tracks was 6 h. The 25.48 m long three-arched bridge was drilled and blasted with 225 number of blastholes (32 mm diameter) and 100 kg explosive (25 mm diameter). Length of blastholes varied between 0.5 and 1.8 m with blast geometry of 0.3-0.35 m burden and 0.33 m spacing. This paper deals with the conceptual and theoretical model developed for identification of the key locations for drilling and implementation of the same. It also discusses about the precautionary measures and the drilling pattern adopted for quick demolition and speedy restoration of tracks.

Spatial Analysis of Rice Blast in China at Three Different Scales.

PubMed

Guo, Fangfang; Chen, Xinglong; Lu, Minghong; Yang, Li; Wang, Shi Wei; Wu, Bo Ming

2018-05-22

In this study, spatial analyses were conducted at three different scales to better understand the epidemiology of rice blast, a major rice disease caused by Magnaporthe oryzae. At regional scale, across the major rice production regions in China, rice blast incidence was monitored on 101 dates at 193 stations from June 10 th to Sep. 10 th during 2009-2014, and surveyed in 143 fields in September, 2016; at county scale, 3 surveys were done covering 1-5 counties in 2015-2016; and at field scale, blast was evaluated in 6 fields in 2015-2016. Spatial cluster and hot spot analyses were conducted in GIS on the geographical pattern of the disease at regional scale, and geostatistical analysis performed at all the three scales. Cluster and hot spot analyses revealed that high-disease areas were clustered in mountainous areas in China. Geostatistical analyses detected spatial dependence of blast incidence with influence ranges of 399 to 1080 km at regional scale, and 5 to 10 m at field scale, but not at county scale. The spatial patterns at different scales might be determined by inherent properties of rice blast and environmental driving forces, and findings from this study provide helpful information to sampling and management of rice blast.

Simplified modeling of blast waves from metalized heterogeneous explosives

NASA Astrophysics Data System (ADS)

Zarei, Z.; Frost, D. L.

2011-09-01

The detonation of a metalized explosive generates a complex multiphase flow field. Modeling the subsequent propagation of the blast front requires a detailed knowledge of the metal particle dynamics and reaction rate. Given the uncertainties in modeling these phenomena, a much simpler, 1D compressible flow model is used to illustrate the general effects of secondary energy release due to particle reaction on the blast front properties. If the total energy release is held constant, the blast pressure and impulse are primarily dependent on the following parameters: the proportion of secondary energy released due to afterburning, the rate of energy release, the location the secondary energy release begins, and the range over which it occurs. Releasing the total energy over a longer time period in general reduces the peak blast overpressure at a given distance. However, secondary energy release reduces the rate of decay of the shock pressure, increases the local gas temperature and hence increases the velocity of the secondary shock front. As a result, for certain values of the above parameters, the peak blast impulse may be increased by a factor of about two in a region near the charge. The largest augmentation to the near-field peak impulse results when the secondary energy is released immediately behind the shock front rather than uniformly within the combustion products.

Cold blast furnace syndrome: a new source of toxic inhalation by nitrogen oxides.

PubMed

Tague, I; Llewellin, P; Burton, K; Buchan, R; Yates, D H

2004-05-01

To describe a new toxic inhalation syndrome in blast furnace workers. Fourteen workers developed acute respiratory symptoms shortly after exposure to "air blast" from blast furnace tuyeres. These included chest tightness, dyspnoea, rigors, and diaphoresis. Chest radiographs showed pulmonary infiltrates, and lung function a restrictive abnormality. This report includes a description of clinical features of the affected workers and elucidation of the probable cause of the outbreak. Clinical features and occupational hygiene measurements suggested the most likely cause was inhalation of nitrogen oxides at high pressure and temperature. While the task could not be eliminated, engineering controls were implemented to control the hazard. No further cases have occurred. "Cold blast furnace syndrome" represents a previously undescribed hazard of blast furnace work, probably due to inhalation of nitrogen oxides. It should be considered in the differential diagnosis of acute toxic inhalational injuries in blast furnace workers.

Effect of Blast Injury on Auditory Localization in Military Service Members.

PubMed

Kubli, Lina R; Brungart, Douglas; Northern, Jerry

Among the many advantages of binaural hearing are the abilities to localize sounds in space and to attend to one sound in the presence of many sounds. Binaural hearing provides benefits for all listeners, but it may be especially critical for military personnel who must maintain situational awareness in complex tactical environments with multiple speech and noise sources. There is concern that Military Service Members who have been exposed to one or more high-intensity blasts during their tour of duty may have difficulty with binaural and spatial ability due to degradation in auditory and cognitive processes. The primary objective of this study was to assess the ability of blast-exposed Military Service Members to localize speech sounds in quiet and in multisource environments with one or two competing talkers. Participants were presented with one, two, or three topic-related (e.g., sports, food, travel) sentences under headphones and required to attend to, and then locate the source of, the sentence pertaining to a prespecified target topic within a virtual space. The listener's head position was monitored by a head-mounted tracking device that continuously updated the apparent spatial location of the target and competing speech sounds as the subject turned within the virtual space. Measurements of auditory localization ability included mean absolute error in locating the source of the target sentence, the time it took to locate the target sentence within 30 degrees, target/competitor confusion errors, response time, and cumulative head motion. Twenty-one blast-exposed Active-Duty or Veteran Military Service Members (blast-exposed group) and 33 non-blast-exposed Service Members and beneficiaries (control group) were evaluated. In general, the blast-exposed group performed as well as the control group if the task involved localizing the source of a single speech target. However, if the task involved two or three simultaneous talkers, localization ability was

Xenon Protects against Blast-Induced Traumatic Brain Injury in an In Vitro Model.

PubMed

Campos-Pires, Rita; Koziakova, Mariia; Yonis, Amina; Pau, Ashni; Macdonald, Warren; Harris, Katie; Edge, Christopher J; Franks, Nicholas P; Mahoney, Peter F; Dickinson, Robert

2018-04-15

The aim of this study was to evaluate the neuroprotective efficacy of the inert gas xenon as a treatment for patients with blast-induced traumatic brain injury in an in vitro laboratory model. We developed a novel blast traumatic brain injury model using C57BL/6N mouse organotypic hippocampal brain-slice cultures exposed to a single shockwave, with the resulting injury quantified using propidium iodide fluorescence. A shock tube blast generator was used to simulate open field explosive blast shockwaves, modeled by the Friedlander waveform. Exposure to blast shockwave resulted in significant (p < 0.01) injury that increased with peak-overpressure and impulse of the shockwave, and which exhibited a secondary injury development up to 72 h after trauma. Blast-induced propidium iodide fluorescence overlapped with cleaved caspase-3 immunofluorescence, indicating that shock-wave-induced cell death involves apoptosis. Xenon (50% atm) applied 1 h after blast exposure reduced injury 24 h (p < 0.01), 48 h (p < 0.05), and 72 h (p < 0.001) later, compared with untreated control injury. Xenon-treated injured slices were not significantly different from uninjured sham slices at 24 h and 72 h. We demonstrate for the first time that xenon treatment after blast traumatic brain injury reduces initial injury and prevents subsequent injury development in vitro. Our findings support the idea that xenon may be a potential first-line treatment for those with blast-induced traumatic brain injury.

Xenon Protects against Blast-Induced Traumatic Brain Injury in an In Vitro Model

PubMed Central

Campos-Pires, Rita; Koziakova, Mariia; Yonis, Amina; Pau, Ashni; Macdonald, Warren; Harris, Katie; Edge, Christopher J.; Franks, Nicholas P.; Mahoney, Peter F.

2018-01-01

Abstract The aim of this study was to evaluate the neuroprotective efficacy of the inert gas xenon as a treatment for patients with blast-induced traumatic brain injury in an in vitro laboratory model. We developed a novel blast traumatic brain injury model using C57BL/6N mouse organotypic hippocampal brain-slice cultures exposed to a single shockwave, with the resulting injury quantified using propidium iodide fluorescence. A shock tube blast generator was used to simulate open field explosive blast shockwaves, modeled by the Friedlander waveform. Exposure to blast shockwave resulted in significant (p < 0.01) injury that increased with peak-overpressure and impulse of the shockwave, and which exhibited a secondary injury development up to 72 h after trauma. Blast-induced propidium iodide fluorescence overlapped with cleaved caspase-3 immunofluorescence, indicating that shock-wave–induced cell death involves apoptosis. Xenon (50% atm) applied 1 h after blast exposure reduced injury 24 h (p < 0.01), 48 h (p < 0.05), and 72 h (p < 0.001) later, compared with untreated control injury. Xenon-treated injured slices were not significantly different from uninjured sham slices at 24 h and 72 h. We demonstrate for the first time that xenon treatment after blast traumatic brain injury reduces initial injury and prevents subsequent injury development in vitro. Our findings support the idea that xenon may be a potential first-line treatment for those with blast-induced traumatic brain injury. PMID:29285980

A drift chamber with a new type of straws for operation in vacuum

NASA Astrophysics Data System (ADS)

Azorskiy, N.; Glonti, L.; Gusakov, Yu.; Elsha, V.; Enik, T.; Kakurin, S.; Kekelidze, V.; Kislov, E.; Kolesnikov, A.; Madigozhin, D.; Movchan, S.; Polenkevich, I.; Potrebenikov, Yu.; Samsonov, V.; Shkarovskiy, S.; Sotnikov, S.; Zinchenko, A.; Danielsson, H.; Bendotti, J.; Degrange, J.; Dixon, N.; Lichard, P.; Morant, J.; Palladino, V.; Gomez, F. Perez; Ruggiero, G.; Vergain, M.

2016-07-01

A 2150×2150 mm2 registration area drift chamber capable of working in vacuum is presented. Thin-wall tubes (straws) of a new type are used in the chamber. A large share of these 9.80 mm diameter drift tubes are made in Dubna from metalized 36 μm Mylar film welded along the generatrix using an ultrasonic welding machine created at JINR. The main features of the chamber and some characteristics of the drift tubes are described. Four such chambers with the X, Y, U, V coordinates each, containing 7168 straws in total, are designed and produced at JINR and CERN. They are installed in the vacuum volume of the NA62 setup in order to study the ultra-rare decay K+ →π+ vv bar and to search for and study rare meson decays. In autumn 2014 the chambers were used for the first time for the data taking in the experimental run of the NA62 at CERN's SPS.

An animal-to-human scaling law for blast-induced traumatic brain injury risk assessment.

PubMed

Jean, Aurélie; Nyein, Michelle K; Zheng, James Q; Moore, David F; Joannopoulos, John D; Radovitzky, Raúl

2014-10-28

Despite recent efforts to understand blast effects on the human brain, there are still no widely accepted injury criteria for humans. Recent animal studies have resulted in important advances in the understanding of brain injury due to intense dynamic loads. However, the applicability of animal brain injury results to humans remains uncertain. Here, we use advanced computational models to derive a scaling law relating blast wave intensity to the mechanical response of brain tissue across species. Detailed simulations of blast effects on the brain are conducted for different mammals using image-based biofidelic models. The intensity of the stress waves computed for different external blast conditions is compared across species. It is found that mass scaling, which successfully estimates blast tolerance of the thorax, fails to capture the brain mechanical response to blast across mammals. Instead, we show that an appropriate scaling variable must account for the mass of protective tissues relative to the brain, as well as their acoustic impedance. Peak stresses transmitted to the brain tissue by the blast are then shown to be a power function of the scaling parameter for a range of blast conditions relevant to TBI. In particular, it is found that human brain vulnerability to blast is higher than for any other mammalian species, which is in distinct contrast to previously proposed scaling laws based on body or brain mass. An application of the scaling law to recent experiments on rabbits furnishes the first physics-based injury estimate for blast-induced TBI in humans.

Carbon Nanotube Reinforced Flexible Windows for Blast Protection

DTIC Science & Technology

2010-07-01

transparent plastic composite for use as a material for window or as a laminate layer in the blast-resistant glazed window. This program focused...materials for window or as a laminate layer in the blast-resistant glazed window. It is obvious that further increasing the mechanical properties of...Dr. Ben Wang led the effort for design/fabrication of windows from the nanotube assembly and lamination experiments. 6 3. RESULTS AND

PaperBLAST: Text Mining Papers for Information about Homologs

DOE PAGES

Price, Morgan N.; Arkin, Adam P.

2017-08-15

Large-scale genome sequencing has identified millions of protein-coding genes whose function is unknown. Many of these proteins are similar to characterized proteins from other organisms, but much of this information is missing from annotation databases and is hidden in the scientific literature. To make this information accessible, PaperBLAST uses EuropePMC to search the full text of scientific articles for references to genes. PaperBLAST also takes advantage of curated resources (Swiss-Prot, GeneRIF, and EcoCyc) that link protein sequences to scientific articles. PaperBLAST’s database includes over 700,000 scientific articles that mention over 400,000 different proteins. Given a protein of interest, PaperBLAST quicklymore » finds similar proteins that are discussed in the literature and presents snippets of text from relevant articles or from the curators. With the recent explosion of genome sequencing data, there are now millions of uncharacterized proteins. If a scientist becomes interested in one of these proteins, it can be very difficult to find information as to its likely function. Often a protein whose sequence is similar, and which is likely to have a similar function, has been studied already, but this information is not available in any database. To help find articles about similar proteins, PaperBLAST searches the full text of scientific articles for protein identifiers or gene identifiers, and it links these articles to protein sequences. Then, given a protein of interest, it can quickly find similar proteins in its database by using standard software (BLAST), and it can show snippets of text from relevant papers. We hope that PaperBLAST will make it easier for biologists to predict proteins’ functions.« less

PaperBLAST: Text Mining Papers for Information about Homologs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Price, Morgan N.; Arkin, Adam P.

Large-scale genome sequencing has identified millions of protein-coding genes whose function is unknown. Many of these proteins are similar to characterized proteins from other organisms, but much of this information is missing from annotation databases and is hidden in the scientific literature. To make this information accessible, PaperBLAST uses EuropePMC to search the full text of scientific articles for references to genes. PaperBLAST also takes advantage of curated resources (Swiss-Prot, GeneRIF, and EcoCyc) that link protein sequences to scientific articles. PaperBLAST’s database includes over 700,000 scientific articles that mention over 400,000 different proteins. Given a protein of interest, PaperBLAST quicklymore » finds similar proteins that are discussed in the literature and presents snippets of text from relevant articles or from the curators. With the recent explosion of genome sequencing data, there are now millions of uncharacterized proteins. If a scientist becomes interested in one of these proteins, it can be very difficult to find information as to its likely function. Often a protein whose sequence is similar, and which is likely to have a similar function, has been studied already, but this information is not available in any database. To help find articles about similar proteins, PaperBLAST searches the full text of scientific articles for protein identifiers or gene identifiers, and it links these articles to protein sequences. Then, given a protein of interest, it can quickly find similar proteins in its database by using standard software (BLAST), and it can show snippets of text from relevant papers. We hope that PaperBLAST will make it easier for biologists to predict proteins’ functions.« less

Considering Bone Marrow Blasts From Nonerythroid Cellularity Improves the Prognostic Evaluation of Myelodysplastic Syndromes.

PubMed

Arenillas, Leonor; Calvo, Xavier; Luño, Elisa; Senent, Leonor; Alonso, Esther; Ramos, Fernando; Ardanaz, María Teresa; Pedro, Carme; Tormo, Mar; Marco, Víctor; Montoro, Julia; Díez-Campelo, María; Brunet, Salut; Arrizabalaga, Beatriz; Xicoy, Blanca; Andreu, Rafael; Bonanad, Santiago; Jerez, Andrés; Nomdedeu, Benet; Ferrer, Ana; Sanz, Guillermo F; Florensa, Lourdes

2016-09-20

WHO classification of myeloid malignancies is based mainly on the percentage of bone marrow (BM) blasts. This is considered from total nucleated cells (TNCs), unless there is erythroid-hyperplasia (erythroblasts ≥ 50%), calculated from nonerythroid cells (NECs). In these instances, when BM blasts are ≥ 20%, the disorder is classified as erythroleukemia, and when BM blasts are < 20%, as myelodysplastic syndrome (MDS). In the latter, the percentage of blasts is considered from TNCs. We assessed the percentage of BM blasts from TNCs and NECs in 3,692 patients with MDS from the Grupo Español de Síndromes Mielodisplásicos, 465 patients with erythroid hyperplasia (MDS-E) and 3,227 patients without erythroid hyperplasia. We evaluated the relevance of both quantifications on classification and prognostication. By enumerating blasts systematically from NECs, 22% of patients with MDS-E and 12% with MDS from the whole series diagnosed within WHO categories with < 5% BM blasts, were reclassified into higher-risk categories and showed a poorer overall survival than did those who remained in initial categories (P = .006 and P = .001, respectively). Following WHO recommendations, refractory anemia with excess blasts (RAEB)-2 diagnosis is not possible in MDS-E, as patients with 10% to < 20% BM blasts from TNCs fulfill erythroleukemia criteria; however, by considering blasts from NECs, 72 patients were recoded as RAEB-2 and showed an inferior overall survival than did patients with RAEB-1 without erythroid hyperplasia. Recalculating the International Prognostic Scoring System by enumerating blasts from NECs in MDS-E and in the overall MDS population reclassified approximately 9% of lower-risk patients into higher-risk categories, which indicated the survival expected for higher-risk patients. Regardless of the presence of erythroid hyperplasia, calculating the percentage of BM blasts from NECs improves prognostic assessment of MDS. This fact should be considered in future

Vacuum probe surface sampler

NASA Technical Reports Server (NTRS)

Zahlava, B. A. (Inventor)

1973-01-01

A vacuum probe surface sampler is described for rapidly sampling relatively large surface areas which possess relatively light loading densities of micro-organism, drug particles or the like. A vacuum head with a hollow handle connected to a suitable vacuum source is frictionally attached to a cone assembly terminating in a flared tip adapted to be passed over the surface to be sampled. A fine mesh screen carried by the vacuum head provides support for a membrane filter which collects the microorganisms or other particles. The head assembly is easily removed from the cone assembly without contacting the cone assembly with human hands.

Fragmentation, Cost and Environmental Effects of Plaster Stemming Method for Blasting at A Basalt Quarry

NASA Astrophysics Data System (ADS)

Cevizci, Halim

2014-10-01

In this study, the plaster stemming application for blasting at a basalt quarry is studied. Drill cuttings are generally used in open pits and quarries as the most common stemming material since these are most readily available at blast sites. However, dry drill cuttings eject very easily from blastholes without offering much resistance to blast energy. The plaster stemming method has been found to be better than the drill cuttings stemming method due to increased confinement inside the hole and better utilization of blast explosive energy in the rock. The main advantage of the new stemming method is the reduction in the cost of blasting. At a basalt quarry, blasting costs per unit volume of rock were reduced to 15% by increasing burden and spacing distances. In addition, better fragmentation was obtained by using the plaster stemming method. Blast trials showed that plaster stemming produced finer material. In the same blast tests, +30 cm size fragments were reduced to 47.3% of the total, compared to 32.6% in the conventional method of drill cuttings stemming. With this method of stemming, vibration and air shock values increased slightly due to more blast energy being available for rock breakage but generally these increased values were small and stayed under the permitted limit for blast damage criteria unless measuring distance is too close.

Electron-cloud build-up in hadron machines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Furman, M.A.

2004-08-09

The first observations of electron-proton coupling effect for coasting beams and for long-bunch beams were made at the earliest proton storage rings at the Budker Institute of Nuclear Physics (BINP) in the mid-60's [1]. The effect was mainly a form of the two-stream instability. This phenomenon reappeared at the CERN ISR in the early 70's, where it was accompanied by an intense vacuum pressure rise. When the ISR was operated in bunched-beam mode while testing aluminum vacuum chambers, a resonant effect was observed in which the electron traversal time across the chamber was comparable to the bunch spacing [2]. Thismore » effect (''beam-induced multipacting''), being resonant in nature, is a dramatic manifestation of an electron cloud sharing the vacuum chamber with a positively-charged beam. An electron-cloud-induced instability has been observed since the mid-80's at the PSR (LANL) [3]; in this case, there is a strong transverse instability accompanied by fast beam losses when the beam current exceeds a certain threshold. The effect was observed for the first time for a positron beam in the early 90's at the Photon Factory (PF) at KEK, where the most prominent manifestation was a coupled-bunch instability that was absent when the machine was operated with an electron beam under otherwise identical conditions [4]. Since then, with the advent of ever more intense positron and hadron beams, and the development and deployment of specialized electron detectors [5-9], the effect has been observed directly or indirectly, and sometimes studied systematically, at most lepton and hadron machines when operated with sufficiently intense beams. The effect is expected in various forms and to various degrees in accelerators under design or construction. The electron-cloud effect (ECE) has been the subject of various meetings [10-15]. Two excellent reviews, covering the phenomenology, measurements, simulations and historical development, have been recently given by Frank

Planar blast scaling with condensed-phase explosives in a shock tube

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, Scott L

2011-01-25

Blast waves are strong shock waves that result from large power density deposition into a fluid. The rapid energy release of high-explosive (HE) detonation provides sufficiently high power density for blast wave generation. Often it is desirable to quantify the energy released by such an event and to determine that energy relative to other reference explosives to derive an explosive-equivalence value. In this study, we use condensed-phase explosives to drive a blast wave in a shock tube. The explosive material and quantity were varied to produce blast waves of differing strengths. Pressure transducers at varying lengths measured the post-shock pressure,more » shock-wave arrival time and sidewall impulse associated with each test. Blast-scaling concepts in a one-dimensional geometry were then used to both determine the energy release associated with each test and to verify the scaling of the shock position versus time, overpressure versus distance, and impulse. Most blast scaling measurements to-date have been performed in a three-dimensional geometry such as a blast arena. Testing in a three-dimensional geometry can be challenging, however, as spherical shock-wave symmetry is required for good measurements. Additionally, the spherical wave strength decays rapidly with distance and it can be necessary to utilize larger (several kg) quantities of explosive to prevent significant decay from occurring before an idealized blast wave has formed. Such a mode of testing can be expensive, require large quantities of explosive, and be limited by both atmospheric conditions (such as rain) and by noise complaints from the population density near the test arena. Testing is possible in more compact geometries, however. Non-planar blast waves can be formed into a quasi-planar shape by confining the shock diffraction with the walls of a shock tube. Regardless of the initial form, the wave shape will begin to approximate a planar front after successive wave reflections from the

Comparison of work rates, energy expenditure, and perceived exertion during a 1-h vacuuming task with a backpack vacuum cleaner and an upright vacuum cleaner.

PubMed

Mengelkoch, Larry J; Clark, Kirby

2006-03-01

The purpose of this study was to evaluate two types of industrial vacuum cleaners, in terms of cleaning rates, energy expenditure, and perceived exertion. Twelve industrial cleaners (six males and six females, age 28-39 yr) performed two 1-h vacuuming tasks with an upright vacuum cleaner (UVC) and a backpack vacuum cleaner (BPVC). Measures for oxygen uptake (VO2) and ratings of perceived exertion (RPE) were collected continuously during the 1-h vacuuming tasks. Cleaning rates for the UVC and BPVC were 7.23 and 14.98 m2min(-1), respectively. On a separate day subjects performed a maximal treadmill exercise test to determine their maximal aerobic capacity (peak VO2). Average absolute energy costs (in Metabolic equivalents), relative energy costs of the vacuum task compared to the subjects' maximal aerobic capacity (% peak VO2), and RPE responses for the 1-h vacuuming tasks were similar between vacuum cleaners, but % peak VO2 and RPE values differed between genders. These results indicate that the BPVC was more efficient than the UVC. With the BPVC, experienced workers vacuumed at a cleaning rate 2.07 times greater than the UVC and had similar levels of energy expenditure and perceived effort, compared to the slower cleaning rate with the UVC.

The Balloon-borne Large Aperture Submillimeter Telescope: BLAST

NASA Astrophysics Data System (ADS)

Truch, Matthew D. P.; Ade, P. A. R.; Bock, J. J.; Chapin, E. L.; Chung, J.; Devlin, M. J.; Dicker, S.; Griffin, M.; Gundersen, J. O.; Halpern, M.; Hargrave, P. C.; Hughes, D. H.; Klein, J.; MacTavish, C. J.; Marsden, G.; Martin, P. G.; Martin, T. G.; Mauskopf, P.; Netterfield, C. B.; Olmi, L.; Pascale, E.; Patanchon, G.; Rex, M.; Scott, D.; Semisch, C.; Thomas, N. E.; Tucker, C.; Tucker, G. S.; Viero, M. P.; Wiebe, D. V.

2009-01-01

The Balloon-borne Large Aperture Submillimeter Telescope (BLAST) is a suborbital surveying experiment designed to study the evolutionary history and processes of star formation in local galaxies (including the Milky Way) and galaxies at cosmological distances. The BLAST continuum camera, which consists of 270 detectors distributed between three arrays, observes simultaneously in broadband (30%) spectral windows at 250, 350, and 500 microns. The optical design is based on a 2 m diameter telescope, providing a diffraction-limited resolution of 30" at 250 microns. The gondola pointing system enables raster mapping of arbitrary geometry, with a repeatable positional accuracy of 30"; postflight pointing reconstruction to <5" rms is achieved. The onboard telescope control software permits autonomous execution of a preselected set of maps, with the option of manual override. On this poster, we describe the primary characteristics and measured in-flight performance of BLAST. BLAST performed a test flight in 2003 and has since made two scientifically productive long-duration balloon flights: a 100 hour flight from ESRANGE (Kiruna), Sweden to Victoria Island, northern Canada in 2005 June; and a 250 hour, circumpolar flight from McMurdo Station, Antarctica in 2006 December. The BLAST collaboration acknowledges the support of NASA through grants NAG5-12785, NAG5-13301, and NNGO-6GI11G, the Canadian Space Agency (CSA), the Science and Technology Facilities Council (STFC), Canada's Natural Sciences and Engineering Research Council (NSERC), the Canada Foundation for Innovation, the Ontario Innovation Trust, the Puerto Rico Space Grant Consortium, the Fondo Institucional para la Investigacion of the University of Puerto Rico, and the National Science Foundation Office of Polar Programs.

Interplay between high energy impulse noise (blast) and antioxidants in the lung.

PubMed

Elsayed, Nabil M; Gorbunov, Nikolai V

2003-07-15

High-energy impulse noise (BLAST) is a physical event characterized by an abrupt rise in atmospheric pressure above ambient lasting for a very short period, but potentially causing significant material and biological damage. Exposure to high-level BLAST can be destructive and lethal. Low-level BLAST similar to what is encountered repeatedly by military personnel during training and combat from detonation of munitions and firing of large caliber weapons, and during occupational use of explosives and some heavy machinery, can also cause significant injury. Globally, civilians are increasingly exposed to BLAST resulting from terrorist bombings or abandoned unmarked mines following numerous wars and conflicts. We have shown previously in several animal models that exposure to non-lethal BLAST results in pathological changes, mostly to the hollow organs characterized in the lungs, the most sensitive organ, by rupture of alveolar septa, and pulmonary hemorrhage and edema. These events potentially can cause alveolar flooding, respiratory insufficiency and adult respiratory distress syndrome (ARDS), leading to varying degrees of hypoxia, antioxidant depletion and oxidative damage. We have also observed progressive formation of nitric oxide in blood and other tissues. The totality of these observations supports our general hypothesis that exposure to BLAST can lead to antioxidant depletion and oxidative damage. Understanding the mechanism(s) of BLAST-induced oxidative stress may have important implications that include a potential beneficial role for antioxidants as a prophylaxis or as secondary treatment of injury after exposure alongside other protective and therapeutic modalities. In addition, it suggests a role for endogenous nitric oxide in the injury. This report reviews experimental evidence of BLAST-induced antioxidant depletion, and the potential benefit from antioxidant supplementation before exposure.

Myeloblastic and lymphoblastic markers in acute undifferentiated leukemia and chronic myelogenous leukemia in blast crisis.

PubMed

Shumak, K H; Baker, M A; Taub, R N; Coleman, M S

1980-11-01

Blast cells were obtained from 17 patients with acute undifferentiated leukemia and 13 patients with chronic myelogenous leukemia in blast crisis. The blasts were tested with anti-i serum in cytotoxicity tests and with antisera to myeloblastic leukemia-associated antigens in immunofluorescence tests. The terminal deoxynucleotidyl transferase (TDT) content of the blasts was also measured. Lymphoblasts react strongly with anti-i, do not react with anti-myeloblast serum, and have high levels of TDT; myeloblasts react weakly with anti-i, do not react with anti-myeloblast serum, and have very low levels of TDT. Of the 17 patients with acute undifferentiated leukemia, there were six with blasts which reacted like lymphoblasts, six with blasts which reacted like myeloblasts, and five with blasts bearing different combinations of these lymphoblastic and myeloblastic markers. Eight of the 11 patients with lymphoblastic or mixed lymphoblastic-myeloblastic markers, but only one of the six with myeloblastic markers, achieved complete or partial remission in response to therapy. Thus, in acute undifferentiated leukemia, classification of blasts with these markers may be of prognostic value. Of the 13 patients with chronic myelogenous leukemia in blast crises, the markers were concordant (for myeloblasts) in only two cases. Three of the 13 patients had TDT-positive blasts, but the reactions of these cells with anti-i and with anti-myeloblast serum differed from those seen with lymphoblasts from patients with acute lymphoblastic leukemia. Although the cell involved in "lymphoid" blast crisis of chronic myelogenous leukemia is similar in many respects to that involved in acute lymphoblastic leukemia, these cells are not identical.

Osteogenic differentiation of periosteum-derived stromal cells in blast-associated traumatic loading

NASA Astrophysics Data System (ADS)

Sory, David R.; Amin, Harsh D.; Rankin, Sara M.; Proud, William G.

2017-06-01

One of the most recurrent medical complications resulting from blast trauma includes blast-induced heterotopic ossification. Heterotopic ossification refers to the pathologic formation of extraskeletal bone in non-osseous tissue. Although a number of studies have established the interaction between mechanics and biology in bone formation following shock trauma, the exact nature of the mechanical stimuli associated to blast-loading and their influence on the activation of osteogenic differentiation of cells remain unanswered. Here we present the design and calibration of a loading platform compatible with living cells to examine the effects of mechanical stress pulses of blast-associated varying strain rates on the activation of osteogenic differentiation of periosteum (PO) cells. Multiaxial compression loadings of PO cells are performed at different magnitudes of stress and ranges of strain rate. A proof of concept is presented so as to establish a new window to address fundamental questions regarding blast injuries at the cellular level. This work was conducted under the auspices of the Royal British Legion Centre for Blast Injury Studies at Imperial College London. The authors would like to acknowledge the financial support of the Royal British Legion.

Recovery Act: ArcelorMittal USA Blast Furnace Gas Flare Capture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seaman, John

2013-01-14

The U.S. Department of Energy (DOE) awarded a financial assistance grant under the American Recovery and Reinvestment Act of 2009 (Recovery Act) to ArcelorMittal USA, Inc. (ArcelorMittal) for a project to construct and operate a blast furnace gas recovery boiler and supporting infrastructure at ArcelorMittal’s Indiana Harbor Steel Mill in East Chicago, Indiana. Blast furnace gas (BFG) is a by-product of blast furnaces that is generated when iron ore is reduced with coke to create metallic iron. BFG has a very low heating value, about 1/10th the heating value of natural gas. BFG is commonly used as a boiler fuel;more » however, before installation of the gas recovery boiler, ArcelorMittal flared 22 percent of the blast furnace gas produced at the No. 7 Blast Furnace at Indiana Harbor. The project uses the previously flared BFG to power a new high efficiency boiler which produces 350,000 pounds of steam per hour. The steam produced is used to drive existing turbines to generate electricity and for other requirements at the facility. The goals of the project included job creation and preservation, reduced energy consumption, reduced energy costs, environmental improvement, and sustainability.« less

Anatomical manifestations of primary blast ocular trauma observed in a postmortem porcine model.

PubMed

Sherwood, Daniel; Sponsel, William E; Lund, Brian J; Gray, Walt; Watson, Richard; Groth, Sylvia L; Thoe, Kimberly; Glickman, Randolph D; Reilly, Matthew A

2014-02-24

We qualitatively describe the anatomic features of primary blast ocular injury observed using a postmortem porcine eye model. Porcine eyes were exposed to various levels of blast energy to determine the optimal conditions for future testing. We studied 53 enucleated porcine eyes: 13 controls and 40 exposed to a range of primary blast energy levels. Eyes were preassessed with B-scan and ultrasound biomicroscopy (UBM) ultrasonography, photographed, mounted in gelatin within acrylic orbits, and monitored with high-speed videography during blast-tube impulse exposure. Postimpact photography, ultrasonography, and histopathology were performed, and ocular damage was assessed. Evidence for primary blast injury was obtained. While some of the same damage was observed in the control eyes, the incidence and severity of this damage in exposed eyes increased with impulse and peak pressure, suggesting that primary blast exacerbated these injuries. Common findings included angle recession, internal scleral delamination, cyclodialysis, peripheral chorioretinal detachments, and radial peripapillary retinal detachments. No full-thickness openings of the eyewall were observed in any of the eyes tested. Scleral damage demonstrated the strongest associative tendency for increasing likelihood of injury with increased overpressure. These data provide evidence that primary blast alone (in the absence of particle impact) can produce clinically relevant ocular damage in a postmortem model. The blast parameters derived from this study are being used currently in an in vivo model. We also propose a new Cumulative Injury Score indicating the clinical relevance of observed injuries.

Ultrastructural brain abnormalities and associated behavioral changes in mice after low-intensity blast exposure.

PubMed

Song, Hailong; Konan, Landry M; Cui, Jiankun; Johnson, Catherine E; Langenderfer, Martin; Grant, DeAna; Ndam, Tina; Simonyi, Agnes; White, Tommi; Demirci, Utkan; Mott, David R; Schwer, Doug; Hubler, Graham K; Cernak, Ibolja; DePalma, Ralph G; Gu, Zezong

2018-07-16

Explosive blast-induced mild traumatic brain injury (mTBI), a "signature wound" of recent military conflicts, commonly affects service members. While past blast injury studies have provided insights into TBI with moderate- to high-intensity explosions, the impact of primary low-intensity blast (LIB)-mediated pathobiology on neurological deficits requires further investigation. Our prior considerations of blast physics predicted ultrastructural injuries at nanoscale levels. Here, we provide quantitative data using a primary LIB injury murine model exposed to open field detonation of 350 g of high-energy explosive C4. We quantified ultrastructural and behavioral changes up to 30 days post blast injury (DPI). The use of an open-field experimental blast generated a primary blast wave with a peak overpressure of 6.76 PSI (46.6 kPa) at a 3-m distance from the center of the explosion, a positive phase duration of approximate 3.0 milliseconds (ms), a maximal impulse of 8.7 PSI × ms and a sharp rising time of 9 × 10 -3  ms, with no apparent impact/acceleration in exposed animals. Neuropathologically, myelinated axonal damage was observed in blast-exposed groups at 7 DPI. Using transmission electron microscopy, we observed and quantified myelin sheath defects and mitochondrial abnormalities at 7 and 30 DPI. Inverse correlations between blast intensities and neurobehavioral outcomes including motor activities, anxiety levels, nesting behavior, spatial learning and memory occurred. These observations uncover unique ultrastructural brain abnormalities and associated behavioral changes due to primary blast injury and provide key insights into its pathogenesis and potential treatment. Copyright © 2018 Elsevier B.V. All rights reserved.

Blasting and Blast Effects in Cold Regions. Part 3. Explosions in Ground Materials

DTIC Science & Technology

1989-05-01

121- York, Ontario: Technical Marketing Services- 123. Explosives, Canadian Industries, 6th edition. Gaffney, E.S. (1984b) Hugoniot of water ice. In...Mines, blasting. U.S. Bureau of Nlines , Report of Insesti- Report of lnsestigations RI 7751. gations 8507. Piekutoiski. A.J. (1974) I.aborator,, scale

Catastrophic eruptions of the directed-blast type at Mount St. Helens, bezymianny and Shiveluch volcanoes

USGS Publications Warehouse

Bogoyavlenskaya, G.E.; Braitseva, O.A.; Melekestsev, I.V.; Kiriyanov, V. Yu; Dan, Miller C.

1985-01-01

This paper describes catastrophic eruptions of Mount St. Helens (1980), Bezymianny (1955-1956), and Shiveluch (1964) volcanoes. A detailed description of eruption stages and their products, as well as the quantitative characteristics of the eruptive process are given. The eruptions under study belong to the directed-blast type. This type is characterized by the catastrophic character of the climatic stage during which a directed blast, accompanied by edifice destruction, the profound ejection of juvenile pyroclastics and the formation of pyroclastic flows, occur. The climatic stage of all three eruptions has similar characteristics, such as duration, kinetic energy of blast (1017-1018 J), the initial velocity of debris ejection, morphology and size of newly-formed craters. But there are also certain differences. At Mount St. Helens the directed blast was preceeded by failure of the edifice and these events produced separable deposits, namely debris avalanche and directed blast deposits which are composed of different materials and have different volumes, thickness and distribution. At Bezymianny, failure did not precede the blast and the whole mass of debris of the old edifice was outburst only by blast. The resulting deposits, represented by the directed blast agglomerate and sand facies, have characteristics of both the debris avalanche and the blast deposit at Mount St. Helens. At Shiveluch directed-blast deposits are represented only by the directed-blast agglomerate; the directed-blast sand facies, or blast proper, seen at Mount St. Helens is absent. During the period of Plinian activity, the total volumes of juvenile material erupted at Mount St. Helens and at Besymianny were roughly comparable and exceeded the volume of juvenile material erupted at Shiveluch, However, the volume of pyroclastic-flow deposits erupted at Mount St. Helens was much less. The heat energy of all three eruptions is comparable: 1.3 ?? 1018, 3.8-4.8 ?? 1018 and 1 ?? 1017 J for

Combining human and machine processes (CHAMP)

NASA Astrophysics Data System (ADS)

Sudit, Moises; Sudit, David; Hirsch, Michael

2015-05-01

Machine Reasoning and Intelligence is usually done in a vacuum, without consultation of the ultimate decision-maker. The late consideration of the human cognitive process causes some major problems in the use of automated systems to provide reliable and actionable information that users can trust and depend to make the best Course-of-Action (COA). On the other hand, if automated systems are created exclusively based on human cognition, then there is a danger of developing systems that don't push the barrier of technology and are mainly done for the comfort level of selected subject matter experts (SMEs). Our approach to combining human and machine processes (CHAMP) is based on the notion of developing optimal strategies for where, when, how, and which human intelligence should be injected within a machine reasoning and intelligence process. This combination is based on the criteria of improving the quality of the output of the automated process while maintaining the required computational efficiency for a COA to be actuated in timely fashion. This research addresses the following problem areas: • Providing consistency within a mission: Injection of human reasoning and intelligence within the reliability and temporal needs of a mission to attain situational awareness, impact assessment, and COA development. • Supporting the incorporation of data that is uncertain, incomplete, imprecise and contradictory (UIIC): Development of mathematical models to suggest the insertion of a cognitive process within a machine reasoning and intelligent system so as to minimize UIIC concerns. • Developing systems that include humans in the loop whose performance can be analyzed and understood to provide feedback to the sensors.

Blast Testing Issues and TBI: Experimental Models That Lead to Wrong Conclusions.

PubMed

Needham, Charles E; Ritzel, David; Rule, Gregory T; Wiri, Suthee; Young, Leanne

2015-01-01

Over the past several years, we have noticed an increase in the number of blast injury studies published in peer-reviewed biomedical journals that have utilized improperly conceived experiments. Data from these studies will lead to false conclusions and more confusion than advancement in the understanding of blast injury, particularly blast neurotrauma. Computational methods to properly characterize the blast environment have been available for decades. These methods, combined with a basic understanding of blast wave phenomena, enable researchers to extract useful information from well-documented experiments. This basic understanding must include the differences and interrelationships of static pressure, dynamic pressure, reflected pressure, and total or stagnation pressure in transient shockwave flows, how they relate to loading of objects, and how they are properly measured. However, it is critical that the research community effectively overcomes the confusion that has been compounded by a misunderstanding of the differences between the loading produced by a free field explosive blast and loading produced by a conventional shock tube. The principles of blast scaling have been well established for decades and when properly applied will do much to repair these problems. This paper provides guidance regarding proper experimental methods and offers insights into the implications of improperly designed and executed tests. Through application of computational methods, useful data can be extracted from well-documented historical tests, and future work can be conducted in a way to maximize the effectiveness and use of valuable biological test data.

A radiation hard vacuum switch

DOEpatents

Boettcher, G.E.

1988-07-19

A vacuum switch with an isolated trigger probe which is not directly connected to the switching electrodes. The vacuum switch within the plasmatron is triggered by plasma expansion initiated by the trigger probe which travels through an opening to reach the vacuum switch elements. The plasma arc created is directed by the opening to the space between the anode and cathode of the vacuum switch to cause conduction. 3 figs.

29 CFR 1926.904 - Storage of explosives and blasting agents.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., electric blasting caps, detonating primers, and primed cartridges shall not be stored in the same magazine... feet of explosives and detonator storage magazine. (d) No explosives or blasting agents shall be... least two modes of exit have been provided. (e) Permanent underground storage magazines shall be at...

Blast Exposure Causes Early and Persistent Aberrant Phospho- and Cleaved-Tau Expression in a Murine Model of Mild Blast-Induced Traumatic Brain Injury

PubMed Central

Huber, Bertrand R.; Meabon, James S.; Martin, Tobin J.; Mourad, Pierre D.; Bennett, Raymond; Kraemer, Brian C.; Cernak, Ibolja; Petrie, Eric C.; Emery, Michael J.; Swenson, Erik R.; Mayer, Cynthia; Mehic, Edin; Peskind, Elaine R.; Cook, David G.

2014-01-01

Mild traumatic brain injury (mTBI) is considered the ‘signature injury’ of combat veterans that have served during the wars in Iraq and Afghanistan. This prevalence of mTBI is due in part to the common exposure to high explosive blasts in combat zones. In addition to the threats of blunt impact trauma caused by flying objects and the head itself being propelled against objects, the primary blast overpressure (BOP) generated by high explosives is capable of injuring the brain. Compared to other means of causing TBI, the pathophysiology of mild-to-moderate BOP is less well understood. To study the consequences of BOP exposure in mice, we employed a well-established approach using a compressed gas-driven shock tube that recapitulates battlefield-relevant open-field BOP. We found that 24 hours post-blast a single mild BOP provoked elevation of multiple phosphor- and cleaved-tau species in neurons, as well as elevating manganese superoxide-dismutase (MnSOD or SOD2) levels, a cellular response to oxidative stress. In hippocampus, aberrant tau species persisted for at least 30 days post-exposure, while SOD2 levels returned to sham control levels. These findings suggest that elevated phospho- and cleaved-tau species may be among the initiating pathologic processes induced by mild blast exposure. These findings may have important implications for efforts to prevent blast-induced insults to the brain from progressing into long-term neurodegenerative disease processes. PMID:23948882

Optimization of transversal phacoemulsification settings in peristaltic mode using a new transversal ultrasound machine.

PubMed

Wright, Dannen D; Wright, Alex J; Boulter, Tyler D; Bernhisel, Ashlie A; Stagg, Brian C; Zaugg, Brian; Pettey, Jeff H; Ha, Larry; Ta, Brian T; Olson, Randall J

2017-09-01

To determine the optimum bottle height, vacuum, aspiration rate, and power settings in the peristaltic mode of the Whitestar Signature Pro machine with Ellips FX tip action (transversal). John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, USA. Experimental study. Porcine lens nuclei were hardened with formalin and cut into 2.0 mm cubes. Lens cubes were emulsified using transversal and fragment removal time (efficiency), and fragment bounces off the tip (chatter) were measured to determine optimum aspiration rate, bottle height, vacuum, and power settings in the peristaltic mode. Efficiency increased in a linear fashion with increasing bottle height and vacuum. The most efficient aspiration rate was 50 mL/min, with 60 mL/min statistically similar. Increasing power increased efficiency up to 90% with increased chatter at 100%. The most efficient values for the settings tested were bottle height at 100 cm, vacuum at 600 mm Hg, aspiration rate of 50 or 60 mL/min, and power at 90%. Copyright © 2017 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

30 CFR 56.6404 - Separation of blasting circuits from power source.

Code of Federal Regulations, 2010 CFR

2010-07-01

... LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL... when closed to fire the blast. (b) Lead wires shall not be connected to the blasting switch until the...

Carbon Dioxide Blast/Vacuum Demilitarization

DTIC Science & Technology

1992-08-01

through a venturi at the opening of the nozzle. The nozzle accelerates the pellets up to supersonic speeds. CONCEPT ORIGINATION: The concept for a...sent td the treatment plant. The kettle also requires a hood to capture the vapor rising from it, which uses a sophisticated air scrubber to remove

Optimization and application of blasting parameters based on the "pushing-wall" mechanism

NASA Astrophysics Data System (ADS)

Ren, Feng-yu; Sow, Thierno Amadou Mouctar; He, Rong-xing; Liu, Xin-rui

2012-10-01

The large structure parameter of a sublevel caving method was used in Beiminghe iron mine. The ores were generally lower than the medium hardness and easy to be drilled and blasted. However, the questions of boulder yield, "pushing-wall" accident rate, and brow damage rate were not effectively controlled in practical blasting. The model test of a similar material shows that the charge concentration of bottom blastholes in the sector is too high; the pushing wall is the fundamental reason for the poor blasting effect. One of the main methods to adjust the explosive distribution is to increase the length of charged blastholes. Therefore, the field tests with respect to increasing the length of uncharged blastholes were made in 12# stope of -95 subsection and 6# stope of Beiminghe iron mine. This paper took the test result of 12# stope as an example to analyze the impact of charge structure on blasting effect and design an appropriate blasting parameter that is to similar to No.12 stope.

Detection of Blast-Related Traumatic Brain Injury in U.S. Military Personnel

DTIC Science & Technology

2011-06-02

hypothesis that blast-related traumatic brain injury causes traumatic axonal injury, using diffusion tensor imaging ( DTI ), an advanced form of magnetic... DTI scanning within 90 days after the injury. All the subjects had primary blast exposure plus another, blast-related mecha- nism of injury (e.g...other injuries but no clinical diagnosis of traumatic brain injury. Results Abnormalities revealed on DTI were consistent with traumatic axonal injury in

Air bearing vacuum seal assembly

DOEpatents

Booth, Rex

1978-01-01

An air bearing vacuum seal assembly capable of rotating at the speed of several thousand revolutions per minute using an air cushion to prevent the rotating and stationary parts from touching, and a two stage differential pumping arrangement to maintain the pressure gradient between the air cushion and the vacuum so that the leak rate into the vacuum is, for example, less than 1 .times. 10.sup.-4 Pa m.sup.3 /s. The air bearing vacuum seal has particular application for mounting rotating targets to an evacuated accelerator beam tube for bombardment of the targets with high-power charged particle beams in vacuum.

Effects of Filtering on Experimental Blast Overpressure Measurements.

PubMed

Alphonse, Vanessa D; Kemper, Andrew R; Duma, Stefan M

2015-01-01

When access to live-fire test facilities is limited, experimental studies of blast-related injuries necessitate the use of a shock tube or Advanced Blast Simulator (ABS) to mimic free-field blast overpressure. However, modeling blast overpressure in a laboratory setting potentially introduces experimental artifacts in measured responses. Due to the high sampling rates required to capture a blast overpressure event, proximity to alternating current (AC-powered electronics) and poorly strain-relieved or unshielded wires can result in artifacts in the recorded overpressure trace. Data in this study were collected for tests conducted on an empty ABS (“Empty Tube”) using high frequency pressure sensors specifically designed for blast loading rates (n=5). Additionally, intraocular overpressure data (“IOP”) were collected for porcine eyes potted inside synthetic orbits located inside the ABS using an unshielded miniature pressure sensor (n=3). All tests were conducted at a 30 psi static overpressure level. A 4th order phaseless low pass Butterworth software filter was applied to the data. Various cutoff frequencies were examined to determine if the raw shock wave parameters values could be preserved while eliminating noise and artifacts. A Fast Fourier Transform (FFT) was applied to each test to examine the frequency spectra of the raw and filtered signals. Shock wave parameters (time of arrival, peak overpressure, positive duration, and positive impulse) were quantified using a custom MATLAB® script. Lower cutoff frequencies attenuated the raw signal, effectively decreasing the peak overpressure and increasing the positive duration. Rise time was not preserved the filtered data. A CFC 6000 filter preserved the remaining shock wave parameters within ±2.5% of the average raw values for the Empty Tube test data. A CFC 7000 filter removed experimental high-frequency artifacts and preserved the remaining shock wave parameters within ±2.5% of the average raw values for

Vacuum-Gauge Connection For Shipping Container

NASA Technical Reports Server (NTRS)

Henry, Robert H.

1990-01-01

External connector enables measurement of vacuum in stored part. Remote-readout connector added to shipping container and connected to thermo-couple vacuum gauge in vacuum-insulated cryogenic line packed in container. Enables monitoring of condition of vacuum without opening container.

Structure, Function, Interaction, Co-evolution of Rice Blast Resistance Genes

USDA-ARS?s Scientific Manuscript database

Rice blast disease caused by the fungal pathogen Magnaporthe oryzae is one of the most destructive rice diseases worldwide. Resistance (R) genes to blast encode proteins that detect pathogen signaling molecules encoded by M. oryzae avirulence (AVR) genes. R genes can be a single or a member of clu...

The Blast Fungus Decoded: Genomes in Flux.

PubMed

Langner, Thorsten; Białas, Aleksandra; Kamoun, Sophien

2018-04-17

Plant disease outbreaks caused by fungi are a chronic threat to global food security. A prime case is blast disease, which is caused by the ascomycete fungus Magnaporthe oryzae (syn. Pyricularia oryzae ), which is infamous as the most destructive disease of the staple crop rice. However, despite its Linnaean binomial name, M. oryzae is a multihost pathogen that infects more than 50 species of grasses. A timely study by P. Gladieux and colleagues (mBio 9:e01219-17, 2018, https://doi.org/10.1128/mBio.01219-17) reports the most extensive population genomic analysis of the blast fungus thus far. M. oryzae consists of an assemblage of differentiated lineages that tend to be associated with particular host genera. Nonetheless, there is clear evidence of gene flow between lineages consistent with maintaining M. oryzae as a single species. Here, we discuss these findings with an emphasis on the ecologic and genetic mechanisms underpinning gene flow. This work also bears practical implications for diagnostics, surveillance, and management of blast diseases. Copyright © 2018 Langner et al.

Synaptic Mechanisms of Blast-Induced Brain Injury

PubMed Central

Przekwas, Andrzej; Somayaji, Mahadevabharath R.; Gupta, Raj K.

2016-01-01

Blast wave-induced traumatic brain injury (TBI) is one of the most common injuries to military personnel. Brain tissue compression/tension due to blast-induced cranial deformations and shear waves due to head rotation may generate diffuse micro-damage to neuro-axonal structures and trigger a cascade of neurobiological events culminating in cognitive and neurodegenerative disorders. Although diffuse axonal injury is regarded as a signature wound of mild TBI (mTBI), blast loads may also cause synaptic injury wherein neuronal synapses are stretched and sheared. This synaptic injury may result in temporary disconnect of the neural circuitry and transient loss in neuronal communication. We hypothesize that mTBI symptoms such as loss of consciousness or dizziness, which start immediately after the insult, could be attributed to synaptic injury. Although empirical evidence is beginning to emerge; the detailed mechanisms underlying synaptic injury are still elusive. Coordinated in vitro–in vivo experiments and mathematical modeling studies can shed light into the synaptic injury mechanisms and their role in the potentiation of mTBI symptoms. PMID:26834697

Results of tests of MTA-2 TPS on the SRB hold-down bolt blast container

NASA Technical Reports Server (NTRS)

Dean, W. G.

1982-01-01

The four solid rocket booster (SRB) hold-down posts are fastened to the mobile launch platform (MLP) with four large nuts. At liftoff the nuts are split with explosive changes to release the SRB/Shuttle. A blast container is placed over the nuts to protect the vehicle from flying debris. The blast container is a reusable part and has to be protected from aerodynamic heating during flight. The thermal protection system (TPS) used to protect these blast containers is cork. Fitting the flat cork sheet to this hemispherical shaped blast container is both time consuming and expensive. Another problem is removing the charred cork and epoxy glue from the blast containers. Replacements of this cork with another TPS material such as MTA-2 was examined. Heating rates along the centerline of the forward facing areas of the blast container were determined. The feasibility of using 1/2 in. MTA-2 on the SRB blast containers for protection from ascent, plume impingement and reentry heating is demonstrated.

NSLS II Vacuum System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ferreira, M.; Doom, L.; Hseuh, H.

2009-09-13

National Synchrotron Light Source II, being constructed at Brookhaven, is a 3-GeV, 500 mA, 3rd generation synchrotron radiation facility with ultra low emittance electron beams. The storage ring vacuum system has a circumference of 792 m and consists of over 250 vacuum chambers with a simulated average operating pressure of less than 1 x 10{sup -9} mbar. A summary of the update design of the vacuum system including girder supports of the chambers, gauges, vacuum pumps, bellows, beam position monitors and simulation of the average pressure will be shown. A brief description of the techniques and procedures for cleaning andmore » mounting the chambers are given.« less

Intercellular interaction mechanisms for the origination of blast crisis in chronic myeloid leukemia

PubMed Central

Sachs, Rainer; Johnsson, Kerstin; Hahnfeldt, Philip; Luo, Janet; Chen, Allen; Hlatky, Lynn

2011-01-01

Chronic myeloid leukemia (CML) is characterized by a specific chromosome translocation, and its pathobiology is considered comparatively well understood. Thus, quantitative analysis of CML and its progression to blast crisis may help elucidate general mechanisms of carcinogenesis and cancer progression. Hitherto it has been widely postulated that CML blast crisis originates mainly via cell-autonomous mechanisms such as secondary mutations or genomic instability, rather than by intercellular interactions. However, recent results suggest that intercellular interactions play an important role in carcinogenesis. In this study, we analyzed alternative mechanisms, including pairwise intercellular interactions, for CML blast crisis origination. A quantitative, mechanistic cell population dynamics model was employed. This model used recent data on imatinib-treated CML; it also used earlier clinical data, not previously incorporated into current mathematical CML/imatinib models. With the pre-imatinib data, which include results on many more blast crises, we obtained evidence that the driving mechanism for blast crisis origination is intercellular interaction between specific cell types. Assuming leukemic-normal interactions resulted in a statistically significant improvement over assuming either cell-autonomous mechanisms or interactions between leukemic cells. This conclusion was robust with regard to changes in the model’s adjustable parameters. Application of the results to patients treated with imatinib suggests that imatinib may act not only on malignant blast precursors, but also, to a limited degree, on the malignant blasts themselves. Major Findings A comprehensive mechanistic model gives evidence that the main driving mechanisms for CML blast crisis origination are interactions between leukemic and normal cells. PMID:21487044

Cerebellar White Matter Abnormalities following Primary Blast Injury in US Military Personnel

PubMed Central

Mac Donald, Christine; Johnson, Ann; Cooper, Dana; Malone, Thomas; Sorrell, James; Shimony, Joshua; Parsons, Matthew; Snyder, Abraham; Raichle, Marcus; Fang, Raymond; Flaherty, Stephen; Russell, Michael; Brody, David L.

2013-01-01

Little is known about the effects of blast exposure on the human brain in the absence of head impact. Clinical reports, experimental animal studies, and computational modeling of blast exposure have suggested effects on the cerebellum and brainstem. In US military personnel with isolated, primary blast-related ‘mild’ traumatic brain injury and no other known insult, we found diffusion tensor MRI abnormalities consistent with cerebellar white matter injury in 3 of 4 subjects. No abnormalities in other brain regions were detected. These findings add to the evidence supporting the hypothesis that primary blast exposure contributes to brain injury in the absence of head impact and that the cerebellum may be particularly vulnerable. However, the clinical effects of these abnormalities cannot be determined with certainty; none of the subjects had ataxia or other detected evidence of cerebellar dysfunction. The details of the blast events themselves cannot be disclosed at this time, thus additional animal and computational modeling will be required to dissect the mechanisms underlying primary blast-related traumatic brain injury. Furthermore, the effects of possible subconcussive impacts and other military-related exposures cannot be determined from the data presented. Thus many aspects of topic will require further investigation. PMID:23409052

An ultra-fast fiber optic pressure sensor for blast event measurements

NASA Astrophysics Data System (ADS)

Wu, Nan; Zou, Xiaotian; Tian, Ye; Fitek, John; Maffeo, Michael; Niezrecki, Christopher; Chen, Julie; Wang, Xingwei

2012-05-01

Soldiers who are exposed to explosions are at risk of suffering traumatic brain injury (TBI). Since the causal relationship between a blast and TBI is poorly understood, it is critical to have sensors that can accurately quantify the blast dynamics and resulting wave propagation through a helmet and skull that are imparted onto and inside the brain. To help quantify the cause of TBI, it is important to record transient pressure data during a blast event. However, very few sensors feature the capabilities of tracking the dynamic pressure transients due to the rapid change of the pressure during blast events, while not interfering with the physical material layers or wave propagation. In order to measure the pressure transients efficiently, a pressure sensor should have a high resonant frequency and a high spatial resolution. This paper describes an ultra-fast fiber optic pressure sensor based on the Fabry-Perot principle for the application of measuring the rapid pressure changes in a blast event. A shock tube experiment performed in US Army Natick Soldier Research, Development and Engineering Center has demonstrated that the resonant frequency of the sensor is 4.12 MHz, which is relatively close to the designed theoretical value of 4.113 MHz. Moreover, the experiment illustrated that the sensor has a rise time of 120 ns, which demonstrates that the sensor is capable of observing the dynamics of the pressure transient during a blast event.

Effective Porosity Measurements by Wet- and Dry-type Vacuum Saturations using Process-Programmable Vacuum Saturation System

NASA Astrophysics Data System (ADS)

Lee, T. J.; Lee, K. S., , Dr; Lee, S. K.

2017-12-01

One of the most important factors in measuring effective porosity by vacuum saturation method is that the air in the pore space can be fully substituted by water during the vacuum saturation process. International Society of Rock Mechanics (ISRM) suggests vacuuming a rock sample submerged in the water, while American Society of Test and Materials (ASTM) vacuuming the sample and water separately and then pour the water to the sample. In this study, we call the former wet-type vacuum saturation (WVS) method and the latter dry-type vacuum saturation (DVS) method, and compare the effective porosity measured by the two different vacuum saturation processes. For that purpose, a vacuum saturation system has been developed, which can support both WVS and DVS by only changing the process by programming. Comparison of effective porosity has been made for a cement mortar and rock samples. As a result, DVS can substitute more void volume to water than WVS, which in turn insists that DVS can provide more exact value of effective porosity than WVS.

Instability of Taylor-Sedov blast waves propagating through a uniform gas

NASA Astrophysics Data System (ADS)

Grun, J.; Stamper, J.; Manka, C.; Resnick, J.; Burris, R.; Crawford, J.; Ripin, B. H.

1991-05-01

An instability in Taylor-Sedov blast waves was measured as the waves propagated through a uniform gas with a low adiabatic index. The first measurements of the instability are given and compared to theoretical predictions. The classical Taylor-Sedov blast waves resulted from the expansion of ablation plasma into an ambient gas from laser-irradiated foils, and photographs were taken using the dark-field imaging method. Visible emission from the blasts were recorded with a four-frame microchannel-plate intensifier camera. Blast waves formed in nitrogen gas are shown to be stable and smooth, whereas the waves propagating through xenon gas are found to be unstable and wrinkled. A power law is fitted to the experimental data, and the adiabatic indices are theorized to cause the different responses in the two gases. The results generally agree with theoretical predictions in spite of some minor discrepancies, and an explanation of the instability mechanism is developed. When the adiabatic index is sufficiently low, the Taylor-Sedov blast waves in a uniform gas will be unstable, and the perturbed amplitudes will grow as a power of time.

Bomb blast, mild traumatic brain injury and psychiatric morbidity: a review.

PubMed

Rosenfeld, Jeffrey V; Ford, Nick L

2010-05-01

Traumatic brain injury (TBI) arising from blast exposure during war is common, and frequently complicated by psychiatric morbidity. There is controversy as to whether mild TBI from blast is different from other causes of mild TBI. Anxiety and affective disorders such as Post-traumatic Stress Disorder (PTSD) and depression are common accompaniments of blast injury with a significant overlap in the diagnostic features of PTSD with post-concussive syndrome (PCS). This review focuses on this overlap and the effects of mild TBI due to bomb blast. Mild TBI may have been over diagnosed by late retrospective review of returned servicemen and women using imprecise criteria. There is therefore a requirement for clear and careful documentation by health professionals of a TBI due to bomb blast shortly after the event so that the diagnosis of TBI can be made with confidence. There is a need for the early recognition of symptoms of PCS, PTSD and depression and early multi-disciplinary interventions focussed on expected return to duties. There also needs to be a continued emphasis on the de-stigmatization of psychological conditions in military personnel returning from deployment. (c) 2009 Elsevier Ltd. All rights reserved.

Mathematical Models of Blast-Induced TBI: Current Status, Challenges, and Prospects

PubMed Central

Gupta, Raj K.; Przekwas, Andrzej

2013-01-01

Blast-induced traumatic brain injury (TBI) has become a signature wound of recent military activities and is the leading cause of death and long-term disability among U.S. soldiers. The current limited understanding of brain injury mechanisms impedes the development of protection, diagnostic, and treatment strategies. We believe mathematical models of blast wave brain injury biomechanics and neurobiology, complemented with in vitro and in vivo experimental studies, will enable a better understanding of injury mechanisms and accelerate the development of both protective and treatment strategies. The goal of this paper is to review the current state of the art in mathematical and computational modeling of blast-induced TBI, identify research gaps, and recommend future developments. A brief overview of blast wave physics, injury biomechanics, and the neurobiology of brain injury is used as a foundation for a more detailed discussion of multiscale mathematical models of primary biomechanics and secondary injury and repair mechanisms. The paper also presents a discussion of model development strategies, experimental approaches to generate benchmark data for model validation, and potential applications of the model for prevention and protection against blast wave TBI. PMID:23755039

VIEW FROM THE SOUTH OF THE #2 BLAST FURNACE AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW FROM THE SOUTH OF THE #2 BLAST FURNACE AND CASTING SEED ON THE LEFT, THE #1 BLAST FURNACE AND CASTING SHED ON THE RIGHT, AND THE STOVES, BOILERS, AND AUXILIARY EQUIPMENT IN THE CENTER. - Sloss-Sheffield Steel & Iron, First Avenue North Viaduct at Thirty-second Street, Birmingham, Jefferson County, AL

Blast Effects on Fires

DTIC Science & Technology

1980-12-01

Film Records..........................33 Discussion and Interpretation..................34 CRIB FIRE EXTINGUISHMENT BY BLAST ................... 36...48 Phototransistor Records ................... 53 Film Records and Visual Observation. ............ 54 v Discussion and Interpretation...deflection by the barrier and a region of reverse flow behind the barrier; film coverage (with fires) indicates that fuel reignition occurs in the large

Cold blast furnace syndrome: a new source of toxic inhalation by nitrogen oxides

PubMed Central

Tague, I; Llewellin, P; Burton, K; Buchan, R; Yates, D

2004-01-01

Methods: Fourteen workers developed acute respiratory symptoms shortly after exposure to "air blast" from blast furnace tuyeres. These included chest tightness, dyspnoea, rigors, and diaphoresis. Chest radiographs showed pulmonary infiltrates, and lung function a restrictive abnormality. This report includes a description of clinical features of the affected workers and elucidation of the probable cause of the outbreak. Results: Clinical features and occupational hygiene measurements suggested the most likely cause was inhalation of nitrogen oxides at high pressure and temperature. While the task could not be eliminated, engineering controls were implemented to control the hazard. No further cases have occurred. Conclusions: "Cold blast furnace syndrome" represents a previously undescribed hazard of blast furnace work, probably due to inhalation of nitrogen oxides. It should be considered in the differential diagnosis of acute toxic inhalational injuries in blast furnace workers. PMID:15090669

A miniature pressure sensor for blast event evaluation

NASA Astrophysics Data System (ADS)

Wu, Nan; Wang, Wenhui; Tian, Ye; Niezrecki, Christopher; Wang, Xingwei

2011-06-01

Traumatic brain injury (TBI) is a great potential threat to people who deal with explosive devices. Protection from TBI has attracted more and more interest. Great efforts have been taken to the studies on the understanding of the propagation of the blast events and its effect on TBI. However, one of the biggest challenges is that the current available pressure sensors are not fast enough to capture the blast wave especially the transient period. This paper reports an ultrafast pressure sensor that could be very useful for analysis of the fast changing blast signal. The sensor is based on Fabry-Perot (FP) principle. It uses a 45º angle polished fiber sitting in a V-groove on a silicon chip. The endface of the angle polished fiber and the diaphragm which is lifted off on the side wall of the V-groove form the FP cavity. The sensor is very small and can be mounted on different locations of a helmet to measure blast pressure simultaneously. The tests were conducted at Natick Soldier Research, Development, and Engineering Center (NSRDEC) in Natick, MA. The sensors were mounted in a shock tube, side by side with the reference sensors, to measure a rapidly increased pressure. The results demonstrated that our sensors' responses agreed well with those from the electrical reference sensors and their response time is comparable.

BLAST and FASTA similarity searching for multiple sequence alignment.

PubMed

Pearson, William R

2014-01-01

BLAST, FASTA, and other similarity searching programs seek to identify homologous proteins and DNA sequences based on excess sequence similarity. If two sequences share much more similarity than expected by chance, the simplest explanation for the excess similarity is common ancestry-homology. The most effective similarity searches compare protein sequences, rather than DNA sequences, for sequences that encode proteins, and use expectation values, rather than percent identity, to infer homology. The BLAST and FASTA packages of sequence comparison programs provide programs for comparing protein and DNA sequences to protein databases (the most sensitive searches). Protein and translated-DNA comparisons to protein databases routinely allow evolutionary look back times from 1 to 2 billion years; DNA:DNA searches are 5-10-fold less sensitive. BLAST and FASTA can be run on popular web sites, but can also be downloaded and installed on local computers. With local installation, target databases can be customized for the sequence data being characterized. With today's very large protein databases, search sensitivity can also be improved by searching smaller comprehensive databases, for example, a complete protein set from an evolutionarily neighboring model organism. By default, BLAST and FASTA use scoring strategies target for distant evolutionary relationships; for comparisons involving short domains or queries, or searches that seek relatively close homologs (e.g. mouse-human), shallower scoring matrices will be more effective. Both BLAST and FASTA provide very accurate statistical estimates, which can be used to reliably identify protein sequences that diverged more than 2 billion years ago.

Comparative genomics and association mapping approaches for blast resistant genes in finger millet using SSRs.

PubMed

Babu, B Kalyana; Dinesh, Pandey; Agrawal, Pawan K; Sood, S; Chandrashekara, C; Bhatt, Jagadish C; Kumar, Anil

2014-01-01

The major limiting factor for production and productivity of finger millet crop is blast disease caused by Magnaporthe grisea. Since, the genome sequence information available in finger millet crop is scarce, comparative genomics plays a very important role in identification of genes/QTLs linked to the blast resistance genes using SSR markers. In the present study, a total of 58 genic SSRs were developed for use in genetic analysis of a global collection of 190 finger millet genotypes. The 58 SSRs yielded ninety five scorable alleles and the polymorphism information content varied from 0.186 to 0.677 at an average of 0.385. The gene diversity was in the range of 0.208 to 0.726 with an average of 0.487. Association mapping for blast resistance was done using 104 SSR markers which identified four QTLs for finger blast and one QTL for neck blast resistance. The genomic marker RM262 and genic marker FMBLEST32 were linked to finger blast disease at a P value of 0.007 and explained phenotypic variance (R²) of 10% and 8% respectively. The genomic marker UGEP81 was associated to finger blast at a P value of 0.009 and explained 7.5% of R². The QTLs for neck blast was associated with the genomic SSR marker UGEP18 at a P value of 0.01, which explained 11% of R². Three QTLs for blast resistance were found common by using both GLM and MLM approaches. The resistant alleles were found to be present mostly in the exotic genotypes. Among the genotypes of NW Himalayan region of India, VHC3997, VHC3996 and VHC3930 were found highly resistant, which may be effectively used as parents for developing blast resistant cultivars in the NW Himalayan region of India. The markers linked to the QTLs for blast resistance in the present study can be further used for cloning of the full length gene, fine mapping and their further use in the marker assisted breeding programmes for introgression of blast resistant alleles into locally adapted cultivars.

The Effects of Repeated Low-Level Blast Exposure on Hearing in Marines

PubMed Central

Kubli, Lina R.; Pinto, Robin L.; Burrows, Holly L.; Littlefield, Philip D.; Brungart, Douglas S.

2017-01-01

Background: The study evaluates a group of Military Service Members specialized in blast explosive training called “Breachers” who are routinely exposed to multiple low-level blasts while teaching breaching at the U.S. Marine Corps in Quantico Virginia. The objective of this study was to determine if there are any acute or long-term auditory changes due to repeated low-level blast exposures used in training. The performance of the instructor group “Breachers” was compared to a control group, “Engineers”. Methods: A total of 11 Breachers and four engineers were evaluated in the study. The participants received comprehensive auditory tests, including pure-tone testing, speech-in-noise (SIN) measures, and central auditory behavioral and objective tests using early and late (P300) auditory evoked potentials over a period of 17 months. They also received shorter assessments immediately following the blast-exposure onsite at Quantico. Results: No acute or longitudinal effects were identified. However, there were some interesting baseline effects found in both groups. Contrary to the expected, the onsite hearing thresholds and distortion product otoacoustic emissions were slightly better at a few frequencies immediately after blast-exposure than measurements obtained with the same equipment weeks to months after each blast-exposure. Conclusions: To date, the current study is the most comprehensive study that evaluates the long-term effects of blast-exposure on hearing. Despite extensive testing to assess changes, the findings of this study suggest that the levels of current exposures used in this military training environment do not seem to have an obvious deleterious effect on hearing. PMID:28937017

Repeated Low-Level Blast Exposure: A Descriptive Human Subjects Study.

PubMed

Carr, Walter; Stone, James R; Walilko, Tim; Young, Lee Ann; Snook, Tianlu Li; Paggi, Michelle E; Tsao, Jack W; Jankosky, Christopher J; Parish, Robert V; Ahlers, Stephen T

2016-05-01

The relationship between repeated exposure to blast overpressure and neurological function was examined in the context of breacher training at the U.S. Marine Corps Weapons Training Battalion Dynamic Entry School. During this training, Students are taught to apply explosive charges to achieve rapid ingress into secured buildings. For this study, both Students and Instructors participated in neurobehavioral testing, blood toxin screening, vestibular/auditory testing, and neuroimaging. Volunteers wore instrumentation during training to allow correlation of human response measurements and blast overpressure exposure. The key findings of this study were from high-memory demand tasks and were limited to the Instructors. Specific tests showing blast-related mean differences were California Verbal Learning Test II, Automated Neuropsychological Assessment Metrics subtests (Match-to-Sample, Code Substitution Delayed), and Delayed Matching-to-Sample 10-second delay condition. Importantly, apparent deficits were paralleled with functional magnetic resonance imaging using the n-back task. The findings of this study are suggestive, but not conclusive, owing to small sample size and effect. The observed changes yield descriptive evidence for potential neurological alterations in the subset of individuals with occupational history of repetitive blast exposure. This is the first study to integrate subject instrumentation for measurement of individual blast pressure exposure, neurocognitive testing, and neuroimaging. Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.

Low-Level Blast Exposure Increases Transient Receptor Potential Vanilloid 1 (TRPV1) Expression in the Rat Cornea

PubMed Central

Por, Elaine D.; Choi, Jae-Hyek; Lund, Brian J.

2016-01-01

ABSTRACT Background: Blast-related ocular injuries sustained by military personnel have led to rigorous efforts to elucidate the effects of blast exposure on neurosensory function. Recent studies have provided some insight into cognitive and visual deficits sustained following blast exposure; however, limited data are available on the effects of blast on pain and inflammatory processes. Investigation of these secondary effects of blast exposure is necessary to fully comprehend the complex pathophysiology of blast-related injuries. The overall purpose of this study is to determine the effects of single and repeated blast exposure on pain and inflammatory mediators in ocular tissues. Methods: A compressed air shock tube was used to deliver a single or repeated blast (68.0 ± 2.7 kPa) to anesthetized rats daily for 5 days. Immunohistochemistry was performed on ocular tissues to determine the expression of the transient receptor potential vanilloid 1 (TRPV1) channel, calcitonin gene-related peptide (CGRP), substance P (SP), and endothelin-1 (ET-1) following single and repeated blast exposure. Neutrophil infiltration and myeloperoxidase (MPO) expression were also assessed in blast tissues via immunohistochemistry and enzyme-linked immunosorbent assay (ELISA) analysis, respectively. Results: TRPV1 expression was increased in rat corneas exposed to both single and repeated blast. Increased secretion of CGRP, SP, and ET-1 was also detected in rat corneas as compared to control. Moreover, repeated blast exposure resulted in neutrophil infiltration in the cornea and stromal layer as compared to control animals. Conclusion: Single and repeated blast exposure resulted in increased expression of TRPV1, CGRP, SP, and ET-1 as well as neutrophil infiltration. Collectively, these findings provide novel insight into the activation of pain and inflammation signaling mediators following blast exposure. PMID:27049881

Identification of major blast resistance genes in the southern US

USDA-ARS?s Scientific Manuscript database

Resistance (R) genes in rice play important roles in preventing infections of rice blast fungus, Magnaporthe oryzae. In order to identify more R genes for different rice growing areas in the Southern US, an extensive field survey of the blast fungus was performed from 2012 to 2013. A total of 500 is...

29 CFR 1926.905 - Loading of explosives or blasting agents.

Code of Federal Regulations, 2012 CFR

2012-07-01

... have contained explosives or blasting agents. (g) No explosives or blasting agents shall be left... no drilling within 50 feet of the hole. (l) When loading a long line of holes with more than one... be left unattended or unprotected. (t) The blaster shall keep an accurate, up-to-date record of...

29 CFR 1926.905 - Loading of explosives or blasting agents.

Code of Federal Regulations, 2013 CFR

2013-07-01

... have contained explosives or blasting agents. (g) No explosives or blasting agents shall be left... no drilling within 50 feet of the hole. (l) When loading a long line of holes with more than one... be left unattended or unprotected. (t) The blaster shall keep an accurate, up-to-date record of...

29 CFR 1926.905 - Loading of explosives or blasting agents.

Code of Federal Regulations, 2014 CFR

2014-07-01

... have contained explosives or blasting agents. (g) No explosives or blasting agents shall be left... no drilling within 50 feet of the hole. (l) When loading a long line of holes with more than one... be left unattended or unprotected. (t) The blaster shall keep an accurate, up-to-date record of...

29 CFR 1926.905 - Loading of explosives or blasting agents.

Code of Federal Regulations, 2011 CFR

2011-07-01

... have contained explosives or blasting agents. (g) No explosives or blasting agents shall be left... no drilling within 50 feet of the hole. (l) When loading a long line of holes with more than one... be left unattended or unprotected. (t) The blaster shall keep an accurate, up-to-date record of...

General and crevice corrosion study of the in-wall shielding materials for ITER vacuum vessel

NASA Astrophysics Data System (ADS)

Joshi, K. S.; Pathak, H. A.; Dayal, R. K.; Bafna, V. K.; Kimihiro, Ioki; Barabash, V.

2012-11-01

Vacuum vessel In-Wall Shield (IWS) will be inserted between the inner and outer shells of the ITER vacuum vessel. The behaviour of IWS in the vacuum vessel especially concerning the susceptibility to crevice of shielding block assemblies could cause rapid and extensive corrosion attacks. Even galvanic corrosion may be due to different metals in same electrolyte. IWS blocks are not accessible until life of the machine after closing of vacuum vessel. Hence, it is necessary to study the susceptibility of IWS materials to general corrosion and crevice corrosion under operations of ITER vacuum vessel. Corrosion properties of IWS materials were studied by using (i) Immersion technique and (ii) Electro-chemical Polarization techniques. All the sample materials were subjected to a series of examinations before and after immersion test, like Loss/Gain weight measurement, SEM analysis, and Optical stereo microscopy, measurement of surface profile and hardness of materials. After immersion test, SS 304B4 and SS 304B7 showed slight weight gain which indicate oxide layer formation on the surface of coupons. The SS 430 material showed negligible weight loss which indicates mild general corrosion effect. On visual observation with SEM and Metallography, all material showed pitting corrosion attack. All sample materials were subjected to series of measurements like Open Circuit potential, Cyclic polarization, Pitting potential, protection potential, Critical anodic current and SEM examination. All materials show pitting loop in OC2 operating condition. However, its absence in OC1 operating condition clearly indicates the activity of chloride ion to penetrate oxide layer on the sample surface, at higher temperature. The critical pitting temperature of all samples remains between 100° and 200°C.

Exposed by Rocket Engine Blasts

NASA Image and Video Library

2012-08-12

This color image from NASA Curiosity rover shows an area excavated by the blast of the Mars Science Laboratory descent stage rocket engines. This is part of a larger, high-resolution color mosaic made from images obtained by Curiosity Mast Camera.

Community response to blasting.

PubMed

Fidell, S; Horonjeff, R; Schultz, T; Teffeteller, S

1983-09-01

Annoyance due to chronic exposure to blast noise and vibration was assessed in residential areas near two surface mines and a quarry. It was found possible to base useful prediction of the prevalence of high annoyance on a metric of outdoor ground vibration related to high centiles of the long term distribution of exposure levels.

Blast Concussion mTBI, Hypopituitarism, and Psychological Health in OIF/OEF Veterans